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EC 3.7.1.21 Details
EC number
3.7.1.21
Accepted name
6-oxocyclohex-1-ene-1-carbonyl-CoA hydratase
Reaction
6-oxocyclohex-1-ene-1-carbonyl-CoA + 2 H2O = 3-hydroxypimeloyl-CoA (overall reaction);;(1a) 6-oxocyclohex-1-ene-1-carbonyl-CoA + H2O = 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA;;(1b) 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA + H2O = 3-hydroxypimeloyl-CoA
Other name(s)
6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase, 6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase (decyclizing)
Systematic name
6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase (ring-opening)
Comment
The enzyme, which participates in the anaerobic benzoyl-CoA degradation pathway in certain organisms, catalyses the addition of one molecule of water to the double bound of 6-oxocyclohex-1-ene-1-carbonyl-CoA followed by the hydrolytic C-C cleavage of the alicyclic ring.
History
created 2014
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EC Tree
1 Oxidoreductases
2 Transferases
3 Hydrolases
3.1 Acting on ester bonds
3.2 Glycosylases
3.3 Acting on ether bonds
3.4 Acting on peptide bonds (peptidases)
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.6 Acting on acid anhydrides
3.6.1 In phosphorus-containing anhydrides
3.6.1.1 inorganic diphosphatase
3.6.1.2 trimetaphosphatase
3.6.1.3 adenosinetriphosphatase
3.6.1.4 created 1961, deleted 1965
3.6.1.5 apyrase
3.6.1.6 nucleoside diphosphate phosphatase
3.6.1.7 acylphosphatase
3.6.1.8 ATP diphosphatase
3.6.1.9 nucleotide diphosphatase
3.6.1.10 endopolyphosphatase
3.6.1.11 exopolyphosphatase
3.6.1.12 dCTP diphosphatase
3.6.1.13 ADP-ribose diphosphatase
3.6.1.14 adenosine-tetraphosphatase
3.6.1.15 nucleoside-triphosphate phosphatase
3.6.1.16 CDP-glycerol diphosphatase
3.6.1.17 bis(5′-nucleosyl)-tetraphosphatase (asymmetrical)
3.6.1.18 FAD diphosphatase
3.6.1.19 nucleoside-triphosphate diphosphatase
3.6.1.20 5′-acylphosphoadenosine hydrolase
3.6.1.21 ADP-sugar diphosphatase
3.6.1.22 NAD+ diphosphatase
3.6.1.23 dUTP diphosphatase
3.6.1.24 nucleoside phosphoacylhydrolase
3.6.1.25 triphosphatase
3.6.1.26 CDP-diacylglycerol diphosphatase
3.6.1.27 undecaprenyl-diphosphate phosphatase
3.6.1.28 thiamine-triphosphatase
3.6.1.29 bis(5′-adenosyl)-triphosphatase
3.6.1.30 m7G(5′)pppN diphosphatase
3.6.1.31 phosphoribosyl-ATP diphosphatase
3.6.1.32 created 1984, deleted 2000
3.6.1.33 created 1984, deleted 2000
3.6.1.34 created 1984, deleted 2000
3.6.1.35 created 1984, deleted 2000
3.6.1.36 created 1984, deleted 2000
3.6.1.37 created 1984, deleted 2000
3.6.1.38 created 1984, deleted 2000
3.6.1.39 thymidine-triphosphatase
3.6.1.40 guanosine-5′-triphosphate,3′-diphosphate phosphatase
3.6.1.41 bis(5′-nucleosyl)-tetraphosphatase (symmetrical)
3.6.1.42 guanosine-diphosphatase
3.6.1.43 dolichyldiphosphatase
3.6.1.44 oligosaccharide-diphosphodolichol diphosphatase
3.6.1.45 UDP-sugar diphosphatase
3.6.1.46 created 2000, deleted 2003
3.6.1.47 created 2000, deleted 2003
3.6.1.48 created 2000, deleted 200
3.6.1.49 created 2000, deleted 2003
3.6.1.50 created 2000, deleted 2003
3.6.1.51 created 2000, deleted 2003
3.6.1.52 diphosphoinositol-polyphosphate diphosphatase
3.6.1.53 Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase
3.6.1.54 UDP-2,3-diacylglucosamine diphosphatase
3.6.1.55 8-oxo-dGTP diphosphatase
3.6.1.56 2-hydroxy-dATP diphosphatase
3.6.1.57 UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose hydrolase
3.6.1.58 8-oxo-dGDP phosphatase
3.6.1.59 5′-(N7-methyl 5′-triphosphoguanosine)-[mRNA] diphosphatase
3.6.1.60 diadenosine hexaphosphate hydrolase (AMP-forming)
3.6.1.61 diadenosine hexaphosphate hydrolase (ATP-forming)
3.6.1.62 5′-(N7-methylguanosine 5′-triphospho)-[mRNA] hydrolase
3.6.1.63 α-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase
3.6.1.64 inosine diphosphate phosphatase
3.6.1.65 (d)CTP diphosphatase
3.6.1.66 XTP/dITP diphosphatase
3.6.1.67 dihydroneopterin triphosphate diphosphatase
3.6.1.68 geranyl diphosphate phosphohydrolase
3.6.1.69 8-oxo-(d)GTP phosphatase
3.6.1.70 guanosine-5′-diphospho-5′-[DNA] diphosphatase
3.6.1.71 adenosine-5′-diphospho-5′-[DNA] diphosphatase
3.6.1.72 DNA-3′-diphospho-5′-guanosine diphosphatase
3.6.1.73 inosine/xanthosine triphosphatase
3.6.1.74 mRNA 5′-phosphatase
3.6.1.75 diacylglycerol diphosphate phosphatase
3.6.2 In sulfonyl-containing anhydrides
3.6.3 Acting on acid anhydrides to catalyse transmembrane movement of substances
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.5 Acting on GTP to facilitate cellular and subcellular movement
3.7 Acting on carbon-carbon bonds
3.7.1 In ketonic substances
3.7.1.1 oxaloacetase
3.7.1.2 fumarylacetoacetase
3.7.1.3 kynureninase
3.7.1.4 phloretin hydrolase
3.7.1.5 acylpyruvate hydrolase
3.7.1.6 acetylpyruvate hydrolase
3.7.1.7 β-diketone hydrolase
3.7.1.8 2,6-dioxo-6-phenylhexa-3-enoate hydrolase
3.7.1.9 2-hydroxymuconate-6-semialdehyde hydrolase
3.7.1.10 cyclohexane-1,3-dione hydrolase
3.7.1.11 cyclohexane-1,2-dione hydrolase
3.7.1.12 cobalt-precorrin 5A hydrolase
3.7.1.13 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase
3.7.1.14 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase
3.7.1.15 (+)-caryolan-1-ol synthase
3.7.1.16 oxepin-CoA hydrolase
3.7.1.17 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase
3.7.1.18 6-oxocamphor hydrolase
3.7.1.19 2,6-dihydroxypseudooxynicotine hydrolase
3.7.1.20 3-fumarylpyruvate hydrolase
3.7.1.21 6-oxocyclohex-1-ene-1-carbonyl-CoA hydratase
3.7.1.22 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (ring-opening)
3.7.1.23 maleylpyruvate hydrolase
3.7.1.24 2,4-diacetylphloroglucinol hydrolase
3.7.1.25 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase
3.7.1.26 2,4-didehydro-3-deoxy-L-rhamnonate hydrolase
3.7.1.27 neryl diphosphate diphosphatase
3.7.1.28 3-oxoisoapionate-4-phosphate transcarboxylase/hydrolase
3.8 Acting on halide bonds
3.9 Acting on phosphorus-nitrogen bonds
3.10 Acting on sulfur-nitrogen bonds
3.11 Acting on carbon-phosphorus bonds
3.12 Acting on sulfur-sulfur bonds
3.13 Acting on carbon-sulfur bonds
4 Lyases
5 Isomerases
6 Ligases
7 Translocases