EC Explorer
[browse EC tree] - [search]
EC 3.1.1.109 Details
show Brenda entryEC number
3.1.1.109
Accepted name
iron(III)-salmochelin esterase
Reaction
(1) iron(III)-[diglucosyl-enterobactin] complex + H2O = iron(III)-[salmochelin S2] complex;;(2) iron(III)-[monoglucosyl-enterobactin] complex + H2O = iron(III)-[monoglucosyl-(2,3-dihydroxybenzoylserine)3] complex;;(3) iron(III)-[salmochelin S2] complex + H2O = iron(III)-[diglucosyl-(2,3-dihydroxybenzoylserine)2] complex + N-(2,3-dihydroxybenzoyl)-L-serine;;(4) iron(III)-[salmochelin S2] complex + H2O = iron(III)-[salmochelin S1] complex + salmochelin SX;;(5) iron(III)-[monoglucosyl-(2,3-dihydroxybenzoylserine)3] complex + H2O = iron(III)-[salmochelin S1] complex + N-(2,3-dihydroxybenzoyl)-L-serine;;(6) iron(III)-[diglucosyl-(2,3-dihydroxybenzoylserine)2] complex + H2O = iron(III)-[salmochelin SX] complex + salmochelin SX
Other name(s)
iroD (gene name),
ferric-salmochelin esterase
Systematic name
iron(III)-salmochelin complex hydrolase
Comment
This bacterial enzyme is present in pathogenic Salmonella species, uropathogenic and avian pathogenic Escherichia coli strains, and certain Klebsiella strains. The enzyme acts on iron(III)-bound enterobactin and C-glucosylated derivatives known as salmochelins. Unlike EC 3.1.1.107, apo-salmochelin esterase (IroE), IroD prefers iron(III)-bound siderophores as substrates, and is assumed to act after the iron-siderophore complexes are imported into the cell. It catalyses several hydrolytic reactions, producing a mixture of iron(III)-[N-(2,3-dihydroxybenzoyl)-L-serine] complex and salmochelin SX.
History
created 2019
back to topEC Tree
1 Oxidoreductases
3 Hydrolases
3.1.1.9 created 1961, deleted 1972 3.1.1.12 created 1961, deleted 1972 3.1.1.16 created 1961, deleted 1972 3.1.1.18 created 1961, deleted 1982 3.1.1.62 created 1989, deleted 1992 3.1.1.69 created 1992, deleted 2002
