EC Explorer

1.3.3.13

albonoursin synthase

cyclo(L-leucyl-L-phenylalanyl) + 2 O₂ = albonoursin + 2 H₂O₂ (overall reaction);;(1a) cyclo(L-leucyl-L-phenylalanyl) + O₂ = cyclo[(Z)-α,β-didehydrophenylalanyl-L-leucyl] + H₂O₂;;(1b) cyclo[(Z)-α,β-didehydrophenylalanyl-L-leucyl] + O₂ = albonoursin + H₂O₂

cyclo(dipeptide):oxygen oxidoreductase, cyclic dipeptide oxidase, AlbA

cyclo(L-leucyl-L-phenylalanyl):oxygen oxidoreductase

A flavoprotein from the bacterium Streptomyces noursei. The enzyme can also oxidize several other cyclo dipeptides, the best being cyclo(L-tryptophyl-L-tryptophyl) and cyclo(L-phenylalanyl-L-phenylalanyl) [1,2].

created 2013