EC Explorer
[browse EC tree] - [search]
EC 4.1.3.42 Details
EC number
4.1.3.42
Accepted name
(4S)-4-hydroxy-2-oxoglutarate aldolase
Reaction
(4S)-4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate
Other name(s)
2-oxo-4-hydroxyglutarate aldolase (ambiguous),
hydroxyketoglutaric aldolase (ambiguous),
4-hydroxy-2-ketoglutaric aldolase (ambiguous),
2-keto-4-hydroxyglutaric aldolase (ambiguous),
4-hydroxy-2-ketoglutarate aldolase (ambiguous),
2-keto-4-hydroxyglutarate aldolase (ambiguous),
2-oxo-4-hydroxyglutaric aldolase (ambiguous),
hydroxyketoglutarate aldolase (ambiguous),
2-keto-4-hydroxybutyrate aldolase (ambiguous),
4-hydroxy-2-oxoglutarate glyoxylate-lyase (ambiguous),
eda (gene name)
Systematic name
(4S)-4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming)
CAS registry number
9030-81-3
Comment
The enzyme from the bacterium Escherichia coli, which is specific for the (S)-enantiomer, is trifunctional, and also catalyses the reaction of EC 4.1.2.14, 2-dehydro-3-deoxy-phosphogluconate aldolase, and the β-decarboxylation of oxaloacetate. cf. EC 4.1.3.16, 4-hydroxy-2-oxoglutarate aldolase.
History
created 2013
EC Tree
1.3.99.9 created 1976, deleted 2002