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EC 3.6.4.13 Details
EC number
3.6.4.13
Accepted name
RNA helicase
Reaction
ATP + H2O = ADP + phosphate
Other name(s)
CSFV NS3 helicase,
DBP2,
DbpA,
DDX17,
DDX25,
DDX3,
DDX3X,
DDX3Y,
DDX4,
DDX5,
DEAD-box protein DED1,
DEAD-box RNA helicase,
DEAH-box protein 2,
DEAH-box RNA helicase,
DED1,
Dex(H/D) RNA helicase,
EhDEAD1,
EhDEAD1 RNA helicase,
eIF4A helicase,
KOKV helicase,
Mtr4p,
nonstructural protein 3 helicase,
NPH-II,
RHA,
RNA helicase A,
RNA helicase DDX3,
RNA helicase Hera,
RNA-dependent ATPase,
TGBp1 NTPase/helicase domain,
VRH1,
GRTH/DDX25
Systematic name
ATP phosphohydrolase (RNA helix unwinding)
Comment
RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. Some of them unwind RNA with a 3′ to 5′ polarity [3], other show 5′ to 3′ polarity [8]. Some helicases unwind DNA as well as RNA [7,8]. May be identical with EC 3.6.4.12 (DNA helicase).
History
created 2009
EC Tree
1.1.5.1 created 1983, deleted 2002