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EC 3.1.1.78 Details
EC number
3.1.1.78
Accepted name
polyneuridine-aldehyde esterase
Reaction
polyneuridine aldehyde + H2O = 16-epivellosimine + CO2 + methanol
Other name(s)
polyneuridine aldehyde esterase, PNAE
Systematic name
polyneuridine aldehyde hydrolase (decarboxylating)
CAS registry number
87041-55-2
Comment
Following hydrolysis of this indole alkaloid ester the carboxylic acid decarboxylates spontaneously giving the sarpagan skeleton. The enzyme also acts on akuammidine aldehyde (the 16-epimer of polyneuridine aldehyde).
History
created 2002
EC Tree
3.1.1.9 created 1961, deleted 1972
3.1.1.12 created 1961, deleted 1972
3.1.1.16 created 1961, deleted 1972
3.1.1.18 created 1961, deleted 1982
3.1.1.62 created 1989, deleted 1992
3.1.1.69 created 1992, deleted 2002
3.1.23.1 created 1978, deleted 1984
3.1.23.2 created 1978, deleted 1984
3.1.23.3 created 1978, deleted 1984
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3.1.23.10 created 1978, deleted 1984
3.1.23.11 created 1978, deleted 1984
3.1.23.12 created 1978, modified 1982, deleted 1984
3.1.23.13 created 1978, deleted 1984
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3.1.23.30 created 1978, modified 1982, deleted 1984
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3.1.23.43 created 1978, modified 1982, deleted 1984
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3.1.23.45 created 1978, modified 1982, deleted 1984
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3.1.23.78 created 1982, deleted 1984
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