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5.3.1.26: galactose-6-phosphate isomerase

This is an abbreviated version!
For detailed information about galactose-6-phosphate isomerase, go to the full flat file.

Word Map on EC 5.3.1.26

Reaction

D-galactose 6-phosphate
=
D-tagatose 6-phosphate

Synonyms

D-galactose 6-phosphate isomerase, D-galactose-6-phosphate isomerase, D-galactose-6-phosphate ketol-isomerase, galactose-6-phosphate isomerase, GPI, Isomerase, galactose 6-phosphate, LacAB, tagatose-6-phosphate isomerase

ECTree

     5 Isomerases
         5.3 Intramolecular oxidoreductases
             5.3.1 Interconverting aldoses and ketoses, and related compounds
                5.3.1.26 galactose-6-phosphate isomerase

Engineering

Engineering on EC 5.3.1.26 - galactose-6-phosphate isomerase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
H96A
the mutant exhibits 25fold lower activity compared with the wild type enzyme activity
N97A
the mutant has an activity level of approximately 30% that of the wild type enzyme
T67A
the catalytic activity of the mutant is approximately 20fold lower than that of the wild type enzyme
D158G
-
mutation enhances the activity of the enzyme by more than 20%
F160S
-
mutation enhances the activity of the enzyme by more than 20%
G132D
-
mutation enhances the activity of the enzyme by more than 20%
V54A
-
mutation enhances the activity of the enzyme by more than 20%