5.1.99.3: allantoin racemase

This is an abbreviated version!
For detailed information about allantoin racemase, go to the full flat file.

Word Map on EC 5.1.99.3

Reaction

(S)(+)-allantoin
=
(R)(-)-allantoin

Synonyms

Racemase, allantoin, HpxA, allantoin racemase, HpxA enzyme, AllR, BFW91_04965, KPN_01788

ECTree

     5 Isomerases
         5.1 Racemases and epimerases
             5.1.99 Acting on other compounds
                5.1.99.3 allantoin racemase

Engineering

Engineering on EC 5.1.99.3 - allantoin racemase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
C184S
-
the mutation leads to total loss of activity
C79S
-
the mutation leads to total loss of activity
C79S/C184S
-
the double mutation leads to total loss of activity
C184S
-
the mutation leads to total loss of activity
-
C79S
-
the mutation leads to total loss of activity
-
C79S/C184S
-
the double mutation leads to total loss of activity
-
C184S
Klebsiella pneumoniae subsp. pneumoniae Trevisan MGH78578
-
the mutation leads to total loss of activity
-
C79S
Klebsiella pneumoniae subsp. pneumoniae Trevisan MGH78578
-
the mutation leads to total loss of activity
-
C79S/C184S
Klebsiella pneumoniae subsp. pneumoniae Trevisan MGH78578
-
the double mutation leads to total loss of activity
-
E78D
mutant shows diminished catalytic activity affecting kcat and KM for both enantiomers
E78Q
loss of catalytic activity
E78D
-
mutant shows diminished catalytic activity affecting kcat and KM for both enantiomers
-
E78Q
-
loss of catalytic activity
-
additional information