3.1.3.39: streptomycin-6-phosphatase

This is an abbreviated version!
For detailed information about streptomycin-6-phosphatase, go to the full flat file.

Reaction

Synonyms

phosphatase, streptomycin 6-, Sm-phosphate phosphatase, SMP Pase, streptomycin 6-phosphate phosphatase, streptomycin 6-phosphate phosphohydrolase, streptomycin-(streptidino)phosphate phosphatase, streptomycin-6-P phosphohydrolase

ECTree

     3 Hydrolases

         3.1 Acting on ester bonds

             3.1.3 Phosphoric-monoester hydrolases

                3.1.3.39 streptomycin-6-phosphatase

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Results	in table
13	AA Sequence
1	CAS Registry Number
13	Inhibitors
1	Localization
1	Metals/Ions
4	Natural Substrates/ Products (Substrates)
17	Organism
4	Pathway
1	Reaction
1	Reaction Type
13	Reference
8	Source Tissue
52	Substrates and Products (Substrate)
7	Synonyms
1	Systematic Name

Substrates Products

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Substrates Products on EC 3.1.3.39 - streptomycin-6-phosphatase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

(N'-amidino)streptidine phosphate + H2O

(N'-amidino)streptidine + phosphate

Streptomyces sp.

-

-

81100

-

-

?

1,3-diamino-1,3-dideoxy-scyllo-inositol + dihydrostreptomycin 6-phosphate

?

Streptomyces bikiniensis

-

-

134855

-

-

?

1,3-diamino-1,3-dideoxy-scyllo-inositol + p-nitrophenyl phosphate

?

Streptomyces bikiniensis

-

-

134855

-

-

?

2-deoxystreptamine + dihydrostreptomycin 6-phosphate

?

Streptomyces bikiniensis

-

-

134855

-

-

?

2-deoxystreptamine + p-nitrophenyl phosphate

?

Streptomyces bikiniensis

-

-

134855

-

-

?

dihydrostreptomycin 3'',6-bisphosphate + H2O

dihydrostreptomycin 3''-phosphate + phosphate

Streptomyces sp.

-

-

81100

-

-

?

dihydrostreptomycin 6-phosphate

dihydrostreptomycin + phosphate

4 entries

dihydrostreptomycin 6-phosphate + H2O

dihydrostreptomycin + phosphate

2 entries

ethanolamine phosphate + H2O

?

4 entries

N-amidinostreptamine phosphate + H2O

N-amidinostreptamine + phosphate

Streptomyces sp.

-

-

81100

-

-

?

N1-amidinostreptamine 6-phosphate + H2O

N1-amidinostreptamine + phosphate

Streptomyces sp.

-

-

81100

-

-

?

O-phosphoryl-Tris + H2O

?

Streptomyces sp.

-

slow hydrolysis

81100

-

-

?

p-nitrophenyl phosphate + H2O

p-nitrophenol + phosphate

4 entries

streptidine 6-phosphate + H2O

dihydrostreptomycin + phosphate

4 entries

streptomycin 6-phosphate + H2O

streptomycin + phosphate

13 entries

streptomycin-3''-phosphate + H2O

streptomycin + phosphate

4 entries

Tris-phosphate + H2O

?

4 entries

additional information

?

-

2 entries

dihydrostreptomycin 6-phosphate

dihydrostreptomycin + phosphate

Streptomyces bikiniensis

-

-

134853

-

-

?

dihydrostreptomycin 6-phosphate

dihydrostreptomycin + phosphate

Streptomyces galbus

-

-

134853

-

-

?

dihydrostreptomycin 6-phosphate

dihydrostreptomycin + phosphate

Streptomyces griseocarneus

-

-

134853

-

-

?

dihydrostreptomycin 6-phosphate

dihydrostreptomycin + phosphate

Streptomyces griseus

-

-

134853

-

-

?

dihydrostreptomycin 6-phosphate + H2O

dihydrostreptomycin + phosphate

Streptomyces bikiniensis

-

final step in streptomycin biosynthesis

134853, 134855

-

-

?

dihydrostreptomycin 6-phosphate + H2O

dihydrostreptomycin + phosphate

Streptomyces sp.

-

-

81100

-

-

?

ethanolamine phosphate + H2O

?

Streptomyces bikiniensis

-

-

134853

-

-

?

ethanolamine phosphate + H2O

?

Streptomyces galbus

-

-

134853

-

-

?

ethanolamine phosphate + H2O

?

Streptomyces griseocarneus

-

-

134853

-

-

?

ethanolamine phosphate + H2O

?

Streptomyces griseus

-

-

134853

-

-

?

p-nitrophenyl phosphate + H2O

p-nitrophenol + phosphate

Streptomyces bikiniensis

-

-

134853

-

-

?

p-nitrophenyl phosphate + H2O

p-nitrophenol + phosphate

Streptomyces galbus

-

-

134853

-

-

?

p-nitrophenyl phosphate + H2O

p-nitrophenol + phosphate

Streptomyces griseocarneus

-

-

134853

-

-

?

p-nitrophenyl phosphate + H2O

p-nitrophenol + phosphate

Streptomyces griseus

-

-

134853

-

-

?

streptidine 6-phosphate + H2O

dihydrostreptomycin + phosphate

Streptomyces bikiniensis

-

-

134853

-

-

?

streptidine 6-phosphate + H2O

dihydrostreptomycin + phosphate

Streptomyces galbus

-

-

134853

-

-

?

streptidine 6-phosphate + H2O

dihydrostreptomycin + phosphate

Streptomyces griseocarneus

-

-

134853

-

-

?

streptidine 6-phosphate + H2O

dihydrostreptomycin + phosphate

Streptomyces griseus

-

-

134853

-

-

?

streptomycin 6-phosphate + H2O

streptomycin + phosphate

Streptomyces bikiniensis

-

-

134853

-

134853

?

streptomycin 6-phosphate + H2O

streptomycin + phosphate

Streptomyces bikiniensis

-

-

134855

-

134855

?

streptomycin 6-phosphate + H2O

streptomycin + phosphate

Streptomyces galbus

-

-

134853

-

134853

?

streptomycin 6-phosphate + H2O

streptomycin + phosphate

Streptomyces glaucescens

-

-

134857

-

134857

?

streptomycin 6-phosphate + H2O

streptomycin + phosphate

Streptomyces griseocarneus

-

-

134853

-

134853

?

streptomycin 6-phosphate + H2O

streptomycin + phosphate

Streptomyces griseus

-

-

134853

-

134853

?

streptomycin 6-phosphate + H2O

streptomycin + phosphate

Streptomyces griseus

-

-

134854

-

134854

?

streptomycin 6-phosphate + H2O

streptomycin + phosphate

Streptomyces griseus

-

-

134857

-

134857

?

streptomycin 6-phosphate + H2O

streptomycin + phosphate

Streptomyces griseus

-

-

134858

-

134858

?

streptomycin 6-phosphate + H2O

streptomycin + phosphate

Streptomyces griseus HUT 6037

-

-

134854

-

134854

?

streptomycin 6-phosphate + H2O

streptomycin + phosphate

Streptomyces lividans

-

-

134858

-

134858

?

streptomycin 6-phosphate + H2O

streptomycin + phosphate

Streptomyces lividans 66

-

-

134858

-

134858

?

streptomycin 6-phosphate + H2O

streptomycin + phosphate

Streptomyces sp.

-

-

81100

-

81100

?

streptomycin-3''-phosphate + H2O

streptomycin + phosphate

Streptomyces bikiniensis

-

-

134853

-

-

?

streptomycin-3''-phosphate + H2O

streptomycin + phosphate

Streptomyces galbus

-

-

134853

-

-

?

streptomycin-3''-phosphate + H2O

streptomycin + phosphate

Streptomyces griseocarneus

-

-

134853

-

-

?

streptomycin-3''-phosphate + H2O

streptomycin + phosphate

Streptomyces griseus

-

-

134853, 134858

-

-

?

Tris-phosphate + H2O

?

Streptomyces bikiniensis

-

-

134853

-

-

?

Tris-phosphate + H2O

?

Streptomyces galbus

-

-

134853

-

-

?

Tris-phosphate + H2O

?

Streptomyces griseocarneus

-

-

134853

-

-

?

Tris-phosphate + H2O

?

Streptomyces griseus

-

-

134853

-

-

?

additional information

?

-

Streptomyces glaucescens

-

the enzyme and its gene might be involved in phosphate-regulation of the streptomycin-formation on both the gene and the enzyme levels

134857

-

-

?

additional information

?

-

Streptomyces griseus

-

the enzyme and its gene might be involved in phosphate-regulation of the streptomycin-formation on both the gene and the enzyme levels

134857

-

-

?