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3.1.1.51: phorbol-diester hydrolase

This is an abbreviated version!
For detailed information about phorbol-diester hydrolase, go to the full flat file.

Word Map on EC 3.1.1.51

Reaction

phorbol 12,13-dibutanoate
+
H2O
=
phorbol 13-butanoate
+
Butanoate

Synonyms

diacylphorbate 12-hydrolase, More, PDE74H, phorbol-12,13-diester 12-ester hydrolase

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.1 Carboxylic-ester hydrolases
                3.1.1.51 phorbol-diester hydrolase

Reference

Reference on EC 3.1.1.51 - phorbol-diester hydrolase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Shoyab, M.; Warren, T.C.; Torado, G.L.
Isolation and characterization of an ester hydrolase active on phorbol diesters from murine liver
J. Biol. Chem.
256
12529-12534
1981
Mus musculus
Manually annotated by BRENDA team
Shoyab, M.; Warren, T.C.; Torado, G.J.
Phorbol-12,13-diester 12-ester hydrolase may prevent tumour promotion by phorbol diesters in skin
Nature
295
152-154
1982
Cavia porcellus, Oryctolagus cuniculus, Mesocricetus auratus, Rattus norvegicus
Manually annotated by BRENDA team
Kadner, S.S.; Katz, J.; Levitz, M.; Finlay, T.H.
The 65-kDa phorbol-diester hydrolase in mouse plasma is esterase 1 and is immunologically distinct from the 56-kDa phorbol-diester hydrolase in mouse liver
J. Biol. Chem.
260
15604-15609
1985
Mus musculus
Manually annotated by BRENDA team