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2.3.2.25: N-terminal E2 ubiquitin-conjugating enzyme

This is an abbreviated version!
For detailed information about N-terminal E2 ubiquitin-conjugating enzyme, go to the full flat file.

Word Map on EC 2.3.2.25

Reaction

S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine
+
[acceptor protein]-N-terminal-amino acid
=
[E1 ubiquitin-activating enzyme]-L-cysteine
+
N-terminal-ubiquitinyl-[acceptor protein]

Synonyms

E2 Ube2w, E2 ubiquitin-conjugating enzyme, Ubc16, UbcH6, UBE2E1, UBE2O, UBE2W, ubiquitin conjugating enzyme, ubiquitin conjugating enzyme E2, ubiquitin-conjugating enzyme (E2), ubiquitin-conjugating enzyme E2, ubiquitin-protein ligase W

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.2 Aminoacyltransferases
                2.3.2.25 N-terminal E2 ubiquitin-conjugating enzyme

Reference

Reference on EC 2.3.2.25 - N-terminal E2 ubiquitin-conjugating enzyme

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Tatham, M.H.; Geoffroy, M.C.; Shen, L.; Plechanovova, A.; Hattersley, N.; Jaffray, E.G.; Palvimo, J.J.; Hay, R.T.
RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation
Nat. Cell Biol.
10
538-546
2008
Homo sapiens (Q96B02)
Manually annotated by BRENDA team
Scaglione, K.M.; Basrur, V.; Ashraf, N.S.; Konen, J.R.; Elenitoba-Johnson, K.S.; Todi, S.V.; Paulson, H.L.
The ubiquitin-conjugating enzyme (E2) Ube2w ubiquitinates the N terminus of substrates
J. Biol. Chem.
288
18784-18788
2013
Homo sapiens
Manually annotated by BRENDA team
Tatham, M.H.; Plechanovova, A.; Jaffray, E.G.; Salmen, H.; Hay, R.T.
Ube2W conjugates ubiquitin to alpha-amino groups of protein N-termini
Biochem. J.
453
137-145
2013
Homo sapiens (Q96B02)
Manually annotated by BRENDA team
Schumacher, F.R.; Wilson, G.; Day, C.L.
The N-terminal extension of UBE2E ubiquitin-conjugating enzymes limits chain assembly
J. Mol. Biol.
425
4099-4111
2013
Homo sapiens (P51965)
Manually annotated by BRENDA team
Lei, B.; Xie, L.; Zhang, S.; Lv, D.; Shu, F.; Deng, Y.
UBE2W down-regulation promotes cell apoptosis and correlates with hypospermatogenesis
Andrologia
52
e13474
2020
Mus musculus (Q8VDW4), Mus musculus, Mus musculus C57 (Q8VDW4)
Manually annotated by BRENDA team
Stewart, M.D.; Ritterhoff, T.; Klevit, R.E.; Brzovic, P.S.
E2 enzymes more than just middle men
Cell Res.
26
423-440
2016
Homo sapiens (Q96B02)
Manually annotated by BRENDA team
Xu, H.; Shi, J.; Gao, H.; Liu, Y.; Yang, Z.; Shao, F.; Dong, N.
The N-end rule ubiquitin ligase UBR2 mediates NLRP1B inflammasome activation by anthrax lethal toxin
EMBO J.
38
e101996
2019
Mus musculus (Q6ZPJ3)
Manually annotated by BRENDA team
Ye, Y.; Klenerman, D.; Finley, D.
N-terminal ubiquitination of amyloidogenic proteins triggers removal of their oligomers by the proteasome holoenzyme
J. Mol. Biol.
432
585-596
2020
Homo sapiens (Q96B02)
Manually annotated by BRENDA team
Wang, B.; Zeng, L.; Merillat, S.A.; Fischer, S.; Ochaba, J.; Thompson, L.M.; Barmada, S.J.; Scaglione, K.M.; Paulson, H.L.
The ubiquitin conjugating enzyme Ube2W regulates solubility of the Huntingtons disease protein, huntingtin
Neurobiol. Dis.
109
127-136
2018
Mus musculus (Q8VDW4), Mus musculus, Mus musculus C57BL/6 (Q8VDW4)
Manually annotated by BRENDA team