1.5.8.1: dimethylamine dehydrogenase
This is an abbreviated version!
For detailed information about dimethylamine dehydrogenase, go to the full flat file.
Word Map on EC 1.5.8.1
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1.5.8.1
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trimethylamine
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hyphomicrobium
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flavin
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dehydrogenases
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prosthetic
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ammonia
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mononucleotide
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demethylase
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formaldehyde
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histamine
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6-s-cysteinyl
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strands
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methylophilus
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n-oxide
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simplex
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methylotrophus
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nocardioides
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cation-pi
- 1.5.8.1
- trimethylamine
- hyphomicrobium
- flavin
- dehydrogenases
-
prosthetic
- ammonia
- mononucleotide
- demethylase
- formaldehyde
- histamine
-
6-s-cysteinyl
- strands
- methylophilus
- n-oxide
- simplex
- methylotrophus
-
nocardioides
-
cation-pi
Reaction
Synonyms
dehydrogenase, dimethylamine, dehydrogenase, dimethylamine (Hyphomicrobium strain X clone pUHA65/pUHB49 gene dmd precursor), dehydrogenase, dimethylamine (Hyphomicrobium strain X clone pUHA65/pUHB49 gene dmd), dimethylamine monooxygenase, DMADH, EC 1.5.99.10
ECTree
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Substrates Products
Substrates Products on EC 1.5.8.1 - dimethylamine dehydrogenase
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REACTION DIAGRAM
dimethylamine + H2O + 2,6-dichlorophenolindophenol
methylamine + formaldehyde + reduced 2,6-dichlorophenolindophenol
dimethylamine + H2O + electron-transfer flavoprotein
methylamine + formaldehyde + reduced electron-transferring flavoprotein
dimethylamine + H2O + electron-transferring flavoprotein
methylamine + formaldehyde + reduced electron-transferring flavoprotein
dimethylamine + H2O + phenazine methosulfate
methylamine + formaldehyde + reduced phenazine methosulfate
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-
-
-
r
N,N,N,N-tetramethyl-o-phenylenediamine + H2O + electron-transfer flavoprotein
?
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-
-
-
r
ethylamine + acetaldehyde + reduced acceptor
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acceptor: phenazine methosulfate, phenazine ethosulfate, methylene blue, N,N,N,N-tetramethyl-o-phenylenediamine
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-
?
diethylamine + H2O + acceptor
ethylamine + acetaldehyde + reduced acceptor
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at 78.3% of the activity with dimethylamine
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-
?
methylamine + formaldehyde + reduced 2,6-dichlorophenolindophenol
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-
-
-
?
dimethylamine + H2O + 2,6-dichlorophenolindophenol
methylamine + formaldehyde + reduced 2,6-dichlorophenolindophenol
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-
-
-
?
methylamine + formaldehyde + reduced acceptor
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acceptor: phenazine methosulfate, phenazine ethosulfate, methylene blue, N,N,N,N-tetramethyl-o-phenylenediamine
-
?
dimethylamine + H2O + acceptor
methylamine + formaldehyde + reduced acceptor
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acceptor: phenazine methosulfate, phenazine ethosulfate, methylene blue, N,N,N,N-tetramethyl-o-phenylenediamine
-
?
methylamine + formaldehyde + reduced electron-transferring flavoprotein
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-
-
-
?
dimethylamine + H2O + electron-transfer flavoprotein
methylamine + formaldehyde + reduced electron-transferring flavoprotein
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-
-
-
?
methylamine + formaldehyde + reduced electron-transferring flavoprotein
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reverse reaction is catalyzed only under anaerobic growth conditions
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-
?
dimethylamine + H2O + electron-transferring flavoprotein
methylamine + formaldehyde + reduced electron-transferring flavoprotein
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reverse reaction is catalyzed only under anaerobic growth conditions
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-
?
?
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acceptor: phenazine methosulfate, phenazine ethosulfate, methylene blue, N,N,N,N-tetramethyl-o-phenylenediamine
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-
?
ethylpropylamine + H2O + acceptor
?
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at 6.8% of the activity with dimethylamine
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-
?
?
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acceptor: phenazine methosulfate, phenazine ethosulfate, methylene blue, N,N,N,N-tetramethyl-o-phenylenediamine
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-
?
methylethanolamine + H2O + acceptor
?
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at 54.2% of the activity with dimethylamine
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-
?
ethylamine + formaldehyde + reduced acceptor
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acceptor: phenazine methosulfate, phenazine ethosulfate, methylene blue, N,N,N,N-tetramethyl-o-phenylenediamine
-
?
methylethylamine + H2O + acceptor
ethylamine + formaldehyde + reduced acceptor
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at 92.1% of the activity with dimethylamine
-
?
methylethylamine + H2O + acceptor
ethylamine + formaldehyde + reduced acceptor
-
acceptor: phenazine methosulfate, phenazine ethosulfate, methylene blue, N,N,N,N-tetramethyl-o-phenylenediamine
-
?
methylethylamine + H2O + acceptor
ethylamine + formaldehyde + reduced acceptor
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at 92.1% of the activity with dimethylamine
-
?
propylamine + formaldehyde + reduced acceptor
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acceptor: phenazine methosulfate, phenazine ethosulfate, methylene blue, N,N,N,N-tetramethyl-o-phenylenediamine
-
-
?
methylpropylamine + H2O + acceptor
propylamine + formaldehyde + reduced acceptor
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at 12.9% of the activity with dimethylamine
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-
?
additional information
?
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cytochrome cCO is not reduced directly by the enzyme
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-
?
additional information
?
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no reaction with primary and tertiary amines and quarternary ammonium salts
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-
?
additional information
?
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when Hyphomicrobium X grows anaerobically on dimethylamine as sole carbon source with nitrate as terminal electron acceptor, the organism gets its energy from the oxidation of the amine substrate by dimethylamine dehydrogenase
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-
?
additional information
?
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no reaction with primary and tertiary amines and quarternary ammonium salts
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-
?
additional information
?
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cytochrome cCO is not reduced directly by the enzyme
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-
?
additional information
?
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when Hyphomicrobium X grows anaerobically on dimethylamine as sole carbon source with nitrate as terminal electron acceptor, the organism gets its energy from the oxidation of the amine substrate by dimethylamine dehydrogenase
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-
?
additional information
?
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anaerobic and aerobic metabolism of ethylamines, overview
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?
additional information
?
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anaerobic and aerobic metabolism of ethylamines, overview
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?