1.5.3.5: (S)-6-hydroxynicotine oxidase
This is an abbreviated version!
For detailed information about (S)-6-hydroxynicotine oxidase, go to the full flat file.
Word Map on EC 1.5.3.5
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1.5.3.5
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arthrobacter
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6-hydroxy-d-nicotine
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nicotinovorans
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oxidans
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flavin
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fad
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flavoenzyme
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nicotine-degrading
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monoamine
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flavoproteins
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hydride
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6-hydroxypseudooxynicotine
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dehydrogenation
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pseudooxynicotine
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d-specific
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pyrrolidine
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dithionite-reduced
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carbon-carbon
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self-formed
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fad-binding
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s-nicotine
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l-enantiomer
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fitzpatrick
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carbon-nitrogen
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isoalloxazine
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6-hdno
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substrate-reduced
- 1.5.3.5
- arthrobacter
- 6-hydroxy-d-nicotine
- nicotinovorans
- oxidans
- flavin
- fad
-
flavoenzyme
-
nicotine-degrading
-
monoamine
- flavoproteins
-
hydride
- 6-hydroxypseudooxynicotine
-
dehydrogenation
- pseudooxynicotine
-
d-specific
- pyrrolidine
-
dithionite-reduced
-
carbon-carbon
-
self-formed
-
fad-binding
-
s-nicotine
-
l-enantiomer
-
fitzpatrick
-
carbon-nitrogen
- isoalloxazine
- 6-hdno
-
substrate-reduced
Reaction
Synonyms
6-HLNO, 6-hydroxy-L-nicotine oxidase, 6-hydroxy-L-nicotine:oxygen oxidoreductase, 6HLNO, flavoprotein nicotine oxidoreductase, L-6-hydroxynicotine oxidase, LHNO, MAO, NdpB, NicA2, NOX, VppB
ECTree
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KCat KM Value
KCat KM Value on EC 1.5.3.5 - (S)-6-hydroxynicotine oxidase
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9.26
mutant R274A/Y311W/C417W, pH 7.4, 22°C
103
(S)-6-hydroxynicotine
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pH 7.0, 25°C, mutant enzyme Y311F
2
-
pH 7.0, 25°C, mutant enzyme N166A
8.6
(S)-6-hydroxynornicotine
-
pH 7.0, 25°C, mutant enzyme Y311F
370
(S)-6-hydroxynornicotine
-
pH 7.0, 25°C, wild-type enzyme
0.0204
(S)-nicotine
mutant R274A/Y311W/C417W, pH 7.4, 22°C
0.0877
(S)-nicotine
mutant R274A/Y311W/C417W, pH 7.4, 37°C
0.048
-
pH 7.0, 25°C, mutant enzyme K287M, cosubstrate: (S)-6-hydroxynicotine
24
O2
-
pH 7.0, 25°C, mutant enzyme N166A, cosubstrate: (S)-6-hydroxynicotine
110
O2
-
pH 7.0, 25°C, mutant enzyme Y311F, cosubstrate: (S)-6-hydroxynicotine
150
O2
-
pH 7.0, 25°C, wild-type enzyme, cosubstrate: (S)-6-hydroxynornicotine
270
O2
-
pH 7.0, 25°C, wild-type enzyme, cosubstrate: (S)-6-hydroxynicotine