1.2.1.103: [amino group carrier protein]-6-phospho-L-2-aminoadipate reductase

This is an abbreviated version!
For detailed information about [amino group carrier protein]-6-phospho-L-2-aminoadipate reductase, go to the full flat file.

Reaction

an [amino group carrier protein]-C-terminal-N-(1-carboxy-5-oxopentan-1-yl)-L-glutamine

an [amino group carrier protein]-C-terminal-N-(1-carboxy-5-phosphooxy-5-oxopentan-1-yl)-L-glutamine

Synonyms

lysY

ECTree

1 Oxidoreductases

1.2 Acting on the aldehyde or oxo group of donors

1.2.1 With NAD⁺ or NADP⁺ as acceptor

1.2.1.103 [amino group carrier protein]-6-phospho-L-2-aminoadipate reductase

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
1263	AA Sequence
2	Cloned(Commentary)
6	Cofactor
1	Crystallization (Commentary)
10	kcat/KM [mM/s]
10	KM Value [mM]
3	Metals/Ions
3	Natural Substrates/ Products (Substrates)
2	Organism
5	Pathway
6	Protein Variants
1	Purification (Commentary)
1	Reaction
2	Reference
3	Substrates and Products (Substrate)
2	Subunits
3	Synonyms
1	Systematic Name
10	Turnover Number [1/s]

Engineering

print visible entries

print all entries

Engineering on EC 1.2.1.103 - [amino group carrier protein]-6-phospho-L-2-aminoadipate reductase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Protein Variants Search

C148A

inactive

H209A

the mutant exhibits similar activity to that of the wildtype enzyme

757173

K271A

Thermus thermophilus

O50146

the mutation results in a 4.6fold decrease in kcat and a 70fold increase in Km value compared to the wild type enzyme

757173

R195A

Thermus thermophilus

O50146

the mutation results in a 5fold decrease in kcat and a 40fold increase in Km value compared to the wild type enzyme

757173

R258A

Thermus thermophilus

O50146

the mutation results in a slight decrease in kcat and a 17fold increase in Km value compared to the wild type enzyme

R278A

inactive