1.17.8.1: hydroxysqualene dehydroxylase
This is an abbreviated version!
For detailed information about hydroxysqualene dehydroxylase, go to the full flat file.
Reaction
Synonyms
hpnE
ECTree
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Systematic Name
Systematic Name on EC 1.17.8.1 - hydroxysqualene dehydroxylase
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squalene:FAD oxidoreductase (hydroxylating)
This enzyme, isolated from the bacteria Rhodopseudomonas palustris and Zymomonas mobilis, participates, along with EC 2.5.1.103, presqualene diphosphate synthase, and EC 4.2.3.156, hydroxysqualene synthase, in the conversion of all-trans-farnesyl diphosphate to squalene. Eukaryotes achieve the same goal in a single step, catalysed by EC 2.5.1.21, squalene synthase.