1.1.1.416: isopyridoxal dehydrogenase (5-pyridoxolactone-forming)

This is an abbreviated version!
For detailed information about isopyridoxal dehydrogenase (5-pyridoxolactone-forming), go to the full flat file.

Reaction

Isopyridoxal
+
NAD+
=
5-Pyridoxolactone
+
NADH
+
H+

Synonyms

isopyridoxal dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.416 isopyridoxal dehydrogenase (5-pyridoxolactone-forming)

Inhibitors

Inhibitors on EC 1.1.1.416 - isopyridoxal dehydrogenase (5-pyridoxolactone-forming)

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
4-deoxyisopyridoxal
-
competitive
5-pyridoxic acid
-
competitive
DTNB
-
0.005 mM, 50% loss of activity after 1 h
HgCl2
-
0.02 mM, 67% loss of activity after 1 h
N-ethylmaleimide
-
2.5 mM, 71% loss of activity after 1 h
NADH
-
noncompetitive
PCMB
-
0.005 mM, 75% loss of activity after 1 h
Thionicotinamide adenine dinucleotide
-
noncompetitive