1.1.1.414: L-galactonate 5-dehydrogenase (NAD+)
This is an abbreviated version!
For detailed information about L-galactonate 5-dehydrogenase (NAD+), go to the full flat file.
Reaction
Synonyms
Bvu0222, L-galactonate dehydrogenase, YjjN
ECTree
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Substrates Products
Substrates Products on EC 1.1.1.414 - L-galactonate 5-dehydrogenase (NAD+)
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REACTION DIAGRAM
L-gluconate + NAD+
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the value of kcat/Km for the oxidation of L-galactonate is 2 orders of magnitude greater than the oxidation of L-gluconate
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D-tagaturonate + NADH + H+
preferred substrate
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L-galactonate + NAD+
D-tagaturonate + NADH + H+
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no activity with NADP+
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L-galactonate + NAD+
D-tagaturonate + NADH + H+
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the enzyme participates in an L-galactonate degradation pathway
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L-galactonate + NAD+
D-tagaturonate + NADH + H+
the enzyme participates in an L-galactonate degradation pathway
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L-galactonate + NAD+
D-tagaturonate + NADH + H+
the enzyme participates in an L-galactonate degradation pathway
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enzyme YjjN is an L-galactonate 5-dehydrogenase having activity also for L-gulonate. Reaction product identification by GC/MS analysis. No activity with substrates of similar structure, L-fuconate and L-lyxonate. And no activity with L-mannonate, L-rhamnonate, D-gulonate, D-galacturonate, D-glucuronate, D-gluconate, D-lyxonate, D-xylonate, D-ribonate, D-arabonate, D-mannonate, D-erythronate, D-glucose, D-xylitol, D-sorbitol, glucooctanic acid, and meso-galactarate. The hydroxyl group at the C6 seems to be essential for the activity
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additional information
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enzyme YjjN is an L-galactonate 5-dehydrogenase having activity also for L-gulonate. Reaction product identification by GC/MS analysis. No activity with substrates of similar structure, L-fuconate and L-lyxonate. And no activity with L-mannonate, L-rhamnonate, D-gulonate, D-galacturonate, D-glucuronate, D-gluconate, D-lyxonate, D-xylonate, D-ribonate, D-arabonate, D-mannonate, D-erythronate, D-glucose, D-xylitol, D-sorbitol, glucooctanic acid, and meso-galactarate. The hydroxyl group at the C6 seems to be essential for the activity
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additional information
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no oxidation of D-arabinonate and L-xylonate
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additional information
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no oxidation of D-arabinonate and L-xylonate
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additional information
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no oxidation of D-arabinonate and L-xylonate
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