EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.8.4.B3 | dabsyl-L-methionine (R)-S-sulfoxide + bovine liver thionein |
NtMsrB1 |
Nicotiana tabacum |
dabsyl-L-methionine + bovine liver thionein + H2O |
- |
? |
1.8.4.B3 | dabsyl-L-methionine (R)-S-sulfoxide + dithiothreitol |
NtMsrB1 |
Nicotiana tabacum |
dabsyl-L-methionine + dithiothreitol disulfide + H2O |
- |
? |
1.8.4.B3 | dabsyl-L-methionine (R)-S-sulfoxide + plant Trx-like protein CDSP32 |
NtMsrB1 |
Nicotiana tabacum |
dabsyl-L-methionine + ? |
- |
? |
1.8.4.B3 | dabsyl-L-methionine (R)-S-sulfoxide + selenocysteamine |
NtMsrB1 |
Nicotiana tabacum |
dabsyl-L-methionine + 2,2'-disulfanediyldiethanamine + H2O |
- |
? |
1.8.4.B3 | L-methionine (R)-S-sulfoxide + dithiothreitol |
- |
Homo sapiens |
L-methionine + dithiothreitol disulfide + H2O |
- |
? |
1.8.4.B3 | L-methionine (R)-S-sulfoxide + thionein |
- |
Homo sapiens |
L-methionine + thionein disulfide + H2O |
- |
? |
1.8.4.B3 | L-methionine (R)-S-sulfoxide + thioredoxin |
reduced thioredoxin is not an efficient reducing agent for hMsrB3. Less than 5% of the activity with dithiothreitol |
Homo sapiens |
L-methionine + thioredoxin disulfide |
- |
? |
1.8.4.B3 | L-methionine (R)-S-sulfoxide + thioredoxin |
reduced thioredoxin is not an efficient reducing agent for hMsrB2. Less than 5% of the activity with dithiothreitol |
Homo sapiens |
L-methionine + thioredoxin disulfide + H2O |
- |
? |
1.8.4.B3 | L-methionine (R)-sulfoxide + dithiothreitol |
- |
Homo sapiens |
L-methionine + dithiothreitol disulfide |
- |
? |
1.8.4.B3 | more |
NtMsrB1 shows very little activity towards L-methionine (R)-sulfoxide. Escherichia coli thioredoxin can not serve as a reducing agent for NtMsrB1. The Trx-independent MsrB enzyme lacks an additional cysteine (resolving cysteine) that is capable of forming a disulfide bond on the enzyme during the catalytic reaction |
Nicotiana tabacum |
? |
- |
? |