Literature summary for 3.4.22.B67 extracted from

Lee, M.T.; Bakir, A.A.; Nguyen, K.N.; Bachant, J.
The SUMO isopeptidase Ulp2p is required to prevent recombination-induced chromosome segregation lethality following DNA replication stress (2011), PLoS Genet., 7, e1001355.

Search for more literature for 3.4.22.B67

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	P40537	-	-

Synonyms

Synonyms	Comment	Organism
SUMO de-conjugating/chain-editing enzyme Ulp2p	-	Saccharomyces cerevisiae
Ulp2p	-	Saccharomyces cerevisiae

General Information

General Information	Comment	Organism
malfunction	spontaneous recombination is elevated in ulp2 strains. Ulp2 mutants display a reduced frequency of chromosome rearrangements. ulp2D mutants fail in chromosome segregation after exposure to methyl methanesulfonate	Saccharomyces cerevisiae
physiological function	role for Ulp2p in preventing the formation of DNA lesions that must be repaired through recombination. Ulp2p is also required to either suppress or resolve recombination-induced attachments between sister chromatids	Saccharomyces cerevisiae

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)