Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | the N-terminal domain is essential for Ulp2 function and is required for nuclear targeting | Saccharomyces cerevisiae | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | P40537 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
polySUMO-protein conjugate + H2O | Ulp2 can cleave the SUMO-SUMO linkage in poly-SUMO chains. The C-terminal noncatalytic domain of Ulp2 is required for efficient depolymerization of large poly-SUMO conjugates in vivo | Saccharomyces cerevisiae | SUMO + truncated polySUMO-protein conjugate + H2O | - |
? |
General Information | Comment | Organism |
---|---|---|
physiological function | Ulp2 is a nuclear protein required for chromosome stability and cell cycle restart after checkpoint arrest | Saccharomyces cerevisiae |