Activating Compound | Comment | Organism | Structure |
---|---|---|---|
cardiolipin | stimulates | Oryctolagus cuniculus | |
dilauroyl phosphatidylcholine | stimulates | Homo sapiens | |
dimyristoyl phosphatidylcholine | stimulates | Homo sapiens | |
dimyristoyl phosphatidylcholine | stimulates | Oryctolagus cuniculus | |
dioleoyl phosphatidylcholine | stimulates | Homo sapiens | |
dioleoyl phosphatidylcholine | stimulates | Oryctolagus cuniculus | |
lecithin | stimulates | Homo sapiens | |
lecithin | stimulates | Oryctolagus cuniculus | |
lysolecithin | stimulates | Homo sapiens | |
lysolecithin | stimulates | Oryctolagus cuniculus | |
phosphatidylethanolamine | stimulates | Homo sapiens | |
phosphatidylethanolamine | stimulates | Oryctolagus cuniculus | |
phosphatidylglycerol | stimulates | Oryctolagus cuniculus | |
phosphatidylsenine | stimulates | Oryctolagus cuniculus | |
sphingomyelin | stimulates | Oryctolagus cuniculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
EDTA | - |
Homo sapiens | |
EDTA | - |
Oryctolagus cuniculus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | Ca2+ is required for catalytic activity and structural stability. Cd2+ or Zn2+ substitute for Ca2+, two Ca2+ binding sites | Homo sapiens | |
Ca2+ | Ca2+ is required for catalytic activity and structural stability. Cd2+ or Zn2+ substitute for Ca2+, two Ca2+ binding sites | Oryctolagus cuniculus | |
Cd2+ | Ca2+ is required for catalytic activity and structural stability. Cd2+ or Zn2+ substitute for Ca2+ | Homo sapiens | |
Cd2+ | Ca2+ is required for catalytic activity and structural stability. Cd2+ or Zn2+ substitute for Ca2+ | Oryctolagus cuniculus | |
Zn2+ | Ca2+ is required for catalytic activity and structural stability. Cd2+ or Zn2+ substitute for Ca2+ | Homo sapiens | |
Zn2+ | Ca2+ is required for catalytic activity and structural stability. Cd2+ or Zn2+ substitute for Ca2+ | Oryctolagus cuniculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
39800 | - |
rabbit serum contains two major species of PON monomers (42300 Da and 39800 Da), SDS-PAGE | Oryctolagus cuniculus |
42300 | - |
rabbit serum contains two major species of PON monomers (42300 Da and 39800 Da), SDS-PAGE | Oryctolagus cuniculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Oryctolagus cuniculus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | at least 2 N-linked sugar chains, contains sialic acid residues | Homo sapiens |
glycoprotein | at least 2 N-linked sugar chains, contains sialic acid residues | Oryctolagus cuniculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood serum | - |
Oryctolagus cuniculus | - |
blood serum | contains A-type paraoxonase and B-type paraoxonase | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-naphthyl acetate + H2O | 0.1% of the activity with phenyl acetate | Oryctolagus cuniculus | 1-naphthol + acetate | - |
? | |
1-naphthyl acetate + H2O | 0.1% of the activity with phenyl acetate, A-type enzyme. 0.25% of the activity with phenyl acetate, B-type enzyme | Homo sapiens | 1-naphthol + acetate | - |
? | |
2-naphthyl acetate + H2O | 13.5% of the activity with phenyl acetate | Oryctolagus cuniculus | 2-naphthol + acetate | - |
? | |
2-naphthyl acetate + H2O | 5.5% of the activity with phenyl acetate, A-type enzyme. 7% of the activity with phenyl acetate, B-type enzyme | Homo sapiens | 2-naphthol + acetate | - |
? | |
2-nitrophenyl acetate + H2O | 2.1% of the activity with phenyl acetate, A-type enzyme. 2% of the activity with phenyl acetate, B-type enzyme | Homo sapiens | 2-nitrophenol + acetate | - |
? | |
2-nitrophenyl acetate + H2O | 29% of the activity with phenyl acetate | Oryctolagus cuniculus | 2-nitrophenol + acetate | - |
? | |
4-nitrophenyl acetate + H2O | 2.5% of the activity with phenyl acetate, A-type enzyme. 3.5% of the activity with phenyl acetate, B-type enzyme | Homo sapiens | 4-nitrophenol + acetate | - |
? | |
4-nitrophenyl acetate + H2O | 31% of the activity with phenyl acetate | Oryctolagus cuniculus | 4-nitrophenol + acetate | - |
? | |
phenyl acetate + H2O | - |
Homo sapiens | phenol + acetate | - |
? | |
phenyl acetate + H2O | - |
Oryctolagus cuniculus | phenol + acetate | - |
? | |
thiophenyl acetate + H2O | 27% of the activity with phenyl acetate, A-type enzyme. 34% of the activity with phenyl acetate, B-type enzyme | Homo sapiens | ? | - |
? | |
thiophenyl acetate + H2O | 30.5% of the activity with phenyl acetate | Oryctolagus cuniculus | ? | - |
? |