Cloned (Comment) | Organism |
---|---|
transient expression in HEK-293 cells | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.096 | - |
2-oxoglutarate | pH 8.0, 37°C, recombinant mitochondrial enzyme | Rattus norvegicus | |
1.63 | - |
pyruvate | pH 8.0, 37°C, recombinant mitochondrial enzyme | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | cDNA encodes for a kynurenine aminotransferase that is identical to a soluble form but carries an additional stretch of 32 amino acids resembling a mitochondrial import sequence | Rattus norvegicus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | Q08415 | brain KAT I | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-kynurenine + 2-oxoglutarate | enzyme has both kynurenine aminotransferase and glutamine transaminase K activity | Rattus norvegicus | kynurenic acid + L-glutamate + H2O | - |
? | |
L-kynurenine + pyruvate | - |
Rattus norvegicus | kynurenic acid + L-alanine + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
KAT | - |
Rattus norvegicus |