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Literature summary for 2.5.1.131 extracted from

  • Wang, Y; Xu, H; Jones, MK; White, R.H.
    Identification of the final two genes functioning in methanofuran biosynthesis in Methanocaldococcus jannaschii (2015), J. Bacteriol., 197, 2850-2858.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.5.1.131

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Methanocaldococcus jannaschii

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
37000
-
 x * 37000, SDS-PAGE Methanocaldococcus jannaschii

Organism

Organism UniProt Comment Textmining
Methanocaldococcus jannaschii Q58250
-
-
Methanocaldococcus jannaschii DSM 2661 Q58250
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information no substrate: tyramine Methanocaldococcus jannaschii ?
-
 ?
additional information no substrate: tyramine Methanocaldococcus jannaschii DSM 2661 ?
-
 ?
[5-(aminomethyl)furan-3-yl]methyl phosphate + gamma-L-glutamyltyramine
-
 Methanocaldococcus jannaschii (4-[4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl]furan-2-yl)methanamine + diphosphate
-
 ?
[5-(aminomethyl)furan-3-yl]methyl phosphate + gamma-L-glutamyltyramine
-
 Methanocaldococcus jannaschii DSM 2661 (4-[4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl]furan-2-yl)methanamine + diphosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 37000, SDS-PAGE Methanocaldococcus jannaschii

Synonyms

Synonyms Comment Organism
MJ0840
-
 Methanocaldococcus jannaschii

General Information

General Information Comment Organism
physiological function enzyme catalyzes the last step in the biosynthesis of methanofuran core structure , i.e. the condensation of 5-(aminomethyl)-3-furanmethanol-diphosphate with gamma-glutamyltyramine, respectively, to form 4-[N-(gamma-L-glutamyl)-p-(beta-aminoethyl)phenoxymethyl]-(aminomethyl)furan. Condensation of the tyramine moiety with 5-(aminomethyl)-3-furanmethanol-diphosphate occurs after formation of gamma-glutamyltyramine Methanocaldococcus jannaschii