Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(4S)-hydroxycitrate | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Rattus norvegicus | |
0.054 | - |
ATP | phosphoenzyme in Hepes buffer, pH 7.6 | Rattus norvegicus | |
0.208 | - |
ATP | dephosphoenzyme in Tris-HCl buffer, pH 8.7 | Rattus norvegicus | |
0.222 | - |
ATP | phosphoenzyme in Tris-HCl buffer, pH 8.7 | Rattus norvegicus | |
0.292 | - |
ATP | dephosphoenzyme in Hepes buffer, pH 7.6 | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | the enzyme tends to associate with the mitochondria | Rattus norvegicus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
side-chain modification | phosphoprotein | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + citrate + CoA | - |
Rattus norvegicus | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
40 | - |
30 min, protein concentration of 0.25 mg/ml, phosphorylated and dephosphorylated form of enzyme, stable | Rattus norvegicus |
45 | - |
10 min, protein concentration of 0.16 mg/ml, phosphorylated and dephosphorylated form of enzyme, 50% loss of activity | Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00005 | - |
(4S)-hydroxycitrate | phospho-form of enzyme | Rattus norvegicus | |
0.00007 | - |
(4S)-hydroxycitrate | dephospho-form of enzyme | Rattus norvegicus |