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Information on EC 5.3.99.4 - prostaglandin-I synthase

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EC Tree
     5 Isomerases
         5.3 Intramolecular oxidoreductases
             5.3.99 Other intramolecular oxidoreductases
                5.3.99.4 prostaglandin-I synthase
IUBMB Comments
A cytochrome P-450 heme-thiolate enzyme. Converts prostaglandin H2 into prostaglandin I2 (prostacyclin).
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
pgis, prostacyclin synthase, pgi2 synthase, ptgis, prostacyclin synthetase, pgi2 synthetase, cyp8a1, pgi synthase, prostaglandin i2 synthase, pgi2-s, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(5Z,13E,15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E,15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate
show the reaction diagram
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