2.7.1.48: uridine/cytidine kinase

This is an abbreviated version!
For detailed information about uridine/cytidine kinase, go to the full flat file.

Reaction

Synonyms

ATP:uridine 5'-phosphotransferase, hsUCK2, kinase, uridine (phosphorylating), More, pyrimidine ribonucleoside kinase, ttCK, UCK, UCK1, UCK2, UCKL1, Udk, UK/UPRT1, uridine cytidine kinase 2, uridine kinase, uridine phosphokinase, uridine-cytidine kinase, uridine-cytidine kinase 2, uridine/cytidine kinase, uridine/cytidine kinase 2

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.48 uridine/cytidine kinase

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Results	in table
3	Activating Compound
21722	AA Sequence
8	Application
1	CAS Registry Number
24	Cloned(Commentary)
13	Cofactor
7	Crystallization (Commentary)
298	Disease/ Diagnostics
3	Expression
39	General Information
7	General Stability
12	IC50 Value
64	Inhibitors
36	kcat/KM [mM/s]
8	Ki Value [mM]
92	KM Value [mM]
6	Localization
49	Metals/Ions
19	Molecular Weight [Da]
68	Natural Substrates/ Products (Substrates)
167	Organism
7	Pathway
48	PDB ID
19	pH Optimum
1	pH Range
1	pH Stability
44	Protein Variants
25	Purification (Commentary)
7	Reaction
1	Reaction Type
62	Reference
102	Source Tissue
13	Specific Activity [micromol/min/mg]
12	Storage Stability
272	Substrates and Products (Substrate)
21	Subunits
71	Synonyms
1	Systematic Name
17	Temperature Optimum [°C]
8	Temperature Stability [°C]
32	Turnover Number [1/s]

Expression

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Expression on EC 2.7.1.48 - uridine/cytidine kinase

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

the enzyme (UCK2) is significantly upregulated in hepatocellular carcinoma tissues compared to adjacent normal tissues

Homo sapiens

Q9BZX2, Q9HA47, Q9NWZ5

761333

the enzyme (UCK2) is significantly upregulated in the deceased group and the recurrence group, compared to the control groups

Homo sapiens

Q9BZX2, Q9HA47, Q9NWZ5

761333

UCKL1 is significantly upregulated in hepatocellular carcinoma tissues compared to adjacent normal tissues

Homo sapiens

Q9BZX2, Q9HA47, Q9NWZ5

761333