2.7.1.193: protein-Npi-phosphohistidine-N-acetyl-D-glucosamine phosphotransferase

This is an abbreviated version!
For detailed information about protein-Npi-phosphohistidine-N-acetyl-D-glucosamine phosphotransferase, go to the full flat file.

Reaction

Synonyms

cbe4532, EC 2.7.1.69, EII permease, EIICBANag, EIINag, enzyme II specific for N-acetylglucosamine, enzyme IIN-acetylglucosamine, enzyme IInag, GlcNAc 6-P deacetylase, GlcNAc PTS, GlcNAc-specific enzyme II, GlcNAc-specific phosphotransferase system transporter, GlcNAc6P-specific transporter of the GlcNAc PTS, N-acetyl-D-glucosamine PTS permease, N-acetylglucosamine-specific transporter nNag, nagE, phosphoenolpyruvate:N-acetylglucosamine phosphotransferase system, ptsN

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.193 protein-Npi-phosphohistidine-N-acetyl-D-glucosamine phosphotransferase

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Results	in table
125	AA Sequence
5	Cloned(Commentary)
3	Expression
2	General Information
2	Inhibitors
1	Localization
2	Molecular Weight [Da]
13	Natural Substrates/ Products (Substrates)
14	Organism
1	Pathway
1	Reaction
13	Reference
13	Substrates and Products (Substrate)
2	Subunits
42	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 2.7.1.193 - protein-Npi-phosphohistidine-N-acetyl-D-glucosamine phosphotransferase

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SYSTEMATIC NAME

IUBMB Comments

protein-Npi-phospho-L-histidine:N-acetyl-D-glucosamine Npi-phosphotransferase

This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS). The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it. The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9 (phosphoenolpyruvate---protein phosphotransferase). Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency. The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.