2.5.1.105: 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase
This is an abbreviated version!
For detailed information about 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase, go to the full flat file.
Reaction
Synonyms
dihydropteroate synthase, MJ0301
ECTree
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Substrates Products
Substrates Products on EC 2.5.1.105 - 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase
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REACTION DIAGRAM
(7,8-dihydropterin-6-yl)methyl diphosphate + 4-(beta-D-ribofuranosyl)aniline 5'-phosphate
N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphate
6-hydroxymethyl-7,8-dihydropterin diphosphate + 1-(4-aminophenyl)-1-deoxy-D-ribitol
7,8-dihydropterin-6-methyl-1-(4-aminophenyl)-1-deoxy-D-ribitol + diphosphate
about 25% of the activity compared to 4-(beta-D-ribofuranosyl)aminobenzene-5'-phosphate
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additional information
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no activity with 4-(beta-D-ribofuranosyl)-aminobenzene
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N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphate
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(7,8-dihydropterin-6-yl)methyl diphosphate + 4-(beta-D-ribofuranosyl)aniline 5'-phosphate
N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphate
the enzyme is involved in the biosynthesis of methanopterin
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