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2.3.2.12: peptidyltransferase

This is an abbreviated version!
For detailed information about peptidyltransferase, go to the full flat file.

Word Map on EC 2.3.2.12

Reaction

Peptidyl-tRNA1
+
aminoacyl-tRNA2
=
tRNA1
+
peptidyl(aminoacyl-tRNA2)

Synonyms

ArfB, L,D-transpeptidase, L,D-transpeptidase 2, LD-transpeptidase, LDT, LdtD, Ldtfm, LdtMt2, LdtMt5, MSMEI_5283, peptidoglycan transpeptidase, peptidyl transferase, peptidyl transferase center, peptidyltransferase centre, PT, PTase, PTC, PTH, ribosomal peptidyl transferase, ribosomal peptidyltransferase, ribosomal protein L27, transpeptidase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.2 Aminoacyltransferases
                2.3.2.12 peptidyltransferase

IC50 Value

IC50 Value on EC 2.3.2.12 - peptidyltransferase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0028
1-ethyl-4-[(2-phenylthiazol-4-yl)methyl]piperazine
Mycolicibacterium smegmatis
-
pH 7.5, 37°C
0.0091
1-[(2-methylthiazol-4-yl)methyl]-4-[(2-phenylthiazol-4-yl)methyl]piperazine
Mycolicibacterium smegmatis
-
pH 7.5, 37°C
0.0071
chloramphenicol
Mycolicibacterium smegmatis
-
pH 7.5, 37°C
0.0003
madumycin II
Escherichia coli
-
pH 7.5, 37°C