2.3.1.220: 2,4,6-trihydroxybenzophenone synthase

This is an abbreviated version!
For detailed information about 2,4,6-trihydroxybenzophenone synthase, go to the full flat file.

Word Map on EC 2.3.1.220

2.3.1.220

falciparum

plasmodium

merozoite

malaria

subunit-based

erythrocyte

aotus

high-activity

receptor-ligand

sporozoite

anti-malarial

multi-stage

protection-inducing

multiepitope

hyaluronan

enzyme-treated

multi-antigenic

hyaluronan-binding

rhoptries

microneme

chemically-synthesized

rhoptry-associated

parasitophorous

Reaction

3 malonyl-CoA +

= 4 CoA +

+ 3 CO2

Synonyms

benzophenone synthase, BPS, HaBPS

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.220 2,4,6-trihydroxybenzophenone synthase

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Results	in table
2	AA Sequence
3	Cloned(Commentary)
2	Crystallization (Commentary)
1	Expression
11	General Information
7	kcat/KM [mM/s]
9	KM Value [mM]
3	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
9	Organism
4	Pathway
2	PDB ID
4	pH Optimum
2	pI Value
15	Protein Variants
1	Purification (Commentary)
2	Reaction
9	Reference
8	Source Tissue
25	Substrates and Products (Substrate)
2	Subunits
11	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
9	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 2.3.1.220 - 2,4,6-trihydroxybenzophenone synthase

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malonyl-CoA:benzoyl-CoA malonyltransferase (2,4,6-trihydroxybenzophenone-forming)

Involved in the biosynthesis of plant xanthones. The enzyme from the plant Hypericum androsaemum L can use 3-hydroxybenzoyl-CoA instead of benzoyl-CoA, but with lower activity (cf. EC 2.3.1.151, 2,3',4,6-tetrahydroxybenzophenone synthase).