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(2,6-dichloro-pyridin-4-yl)-carbamic acid benzyl ester
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(2-chloro-pyridin-4-yl)-carbamic acid 4-chloro-phenyl ester
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1-(2-chloro-1-oxidopyridin-4-yl)-3-phenylurea
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1-imidazo[1,2-a]pyridin-7-yl-3-phenylurea
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2,4-Dichlorophenoxyacetic acid
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inhibits the enzyme by up to 31%
2-amino-6-(3-methoxyanilino)purine
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2-chloro-6-(2-hydroxyanilino)purine
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2-chloro-6-(2-methoxyanilino)purine
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2-chloro-6-(3-chloroanilino)purine
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2-chloro-6-(3-fluoroanilino)purine
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2-chloro-6-(3-hydroxyanilino)purine
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2-chloro-6-(3-methoxyanilino)-9-isopropylpurine
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2-chloro-6-(3-methoxyanilino)-9-methylpurine
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2-chloro-6-(3-methoxyanilino)purine
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2-chloro-6-(4-chloroanilino)purine
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2-chloro-6-(4-fluoroanilino)purine
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2-chloro-6-(4-hydroxyanilino)purine
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2-chloro-6-(4-methoxyanilino)purine
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2-chloro-6-anilinopurine
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2-fluoro-6-(3-methoxyanilino)purine
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2-methylthio-6-(3-methoxyanilino)purine
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2-nitro-6-(3-methoxyanilino)purine
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24-epibrassinolide
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inhibits both cytokinin oxidase activity and expression. Treatment with 0.4 mM 24-epibrassinolide leads to elevated cytokinin levels in roots and shoots, that are maintained only in the presence of 24-epibrassinolide, while the hormone removal leads to return of cytokinin concentration to the control level initially in the roots and then in the shoots
6-(3-methoxyanilino)purine
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adenine
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slight product inhibition
alpha-naphthaleneacetic acid
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inhibits the enzyme by up to 54%
N-(1,2,3-thidiazol-5-yl)-N'-phenylurea
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N-(2,6-dichloro-pyridin-4-yl)-N'-benzylurea
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N-(2,6-dichloro-pyridin-4-yl)-N'-phenoxyurea
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N-(2,6-dichloro-pyridin-4-yl)-N'-phenylurea
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N-(2,6-dichloropyridin-4-yl)-N'-benzyl-N'-methylurea
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N-(2-amino-6-chloro-pyridin-4-yl)-N'-benzylurea
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N-(2-amino-6-chloro-pyridin-4-yl)-N'-phenylurea
one of the most potent inhibitors of CKO
N-(2-amino-pyridin-4-yl)-N'-phenylurea
one of the most potent inhibitors of CKO
N-(2-chloro-4-pyridyl)-N'-phenylurea
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N-(2-chloro-4-pyridyl-N'-5-fluoro-phenylurea)
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N-(2-chloro-6-methoxy-pyridin-4-yl)-N'-benzylurea
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N-(2-chloro-pyridin-4-yl)-N'-benzylurea
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N-(2-chloro-pyridin-4-yl)-N'-phenylurea
the compound binds in a planar conformation and competes for the same binding site with natural substrates
N6-(2-bromo-2-isopentenyl)adenine
weak inhibition
N6-(2-butynyl)adenine
irreversible inhibition
N6-(3-hydroxy-2-phenylethyl)-2-(3-hydroxypropylamino)-9-isopentenyladenine
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N6-(4-hydroxy-2-butynyl)adenine
irreversible inhibition
N6-(buta-2,3-dienyl)adenine
strong irreversible mechanism based inhibition
N6-(penta-2,3-dienyl)adenine
strong irreversible mechanism based inhibition
N6-benzyl-2-(2-hydroxyethylamino)-9-mehtyladenine
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N6-benzyl-2-amino-9-isoproyladenine
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N6-benzyladenine
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strongly stimulates enzyme activity by up to 180%
N6-but-2,3-dienyl-aminopurine
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mechanism-based irreversible (suicide) inhibitor. IC50: 0.02 mM with N6-(2-isopentenyl)adenine as substrate, 0.0004 mM with N6-(2-isopentenyl)adenosine as substrate and less than 0.0001 mM with zeatin as substrate
N6-isopentenyl-N-methylaminopurine
structural analogue of isopentenyladenine
N6-pent-2,3-dienyl aminopurine
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10%, 52%, and 86% inhibition at concentrations of 0.001 mM, 0.01 mM and 0.1 mM
trans-zeatin
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enhances enzyme activity by 35%
thidiazuron
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additional information
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UV-B irradiation reduces enzyme activity
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additional information
cultivation in the presence of gibberillic acid reduces enzyme activity in leaves of cv. Manuela
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additional information
enzyme is strongly inhibited by flavin-protein oxidoreductase inhibitors
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additional information
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enzyme is strongly inhibited by flavin-protein oxidoreductase inhibitors
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