1.3.1.109: butanoyl-CoA dehydrogenase complex (NAD+, ferredoxin)

This is an abbreviated version!
For detailed information about butanoyl-CoA dehydrogenase complex (NAD+, ferredoxin), go to the full flat file.

Word Map on EC 1.3.1.109

1.3.1.109

butyrate

maritima

clostridial

thermotoga

crotonyl-coa

butanol

dehydrogenases

methanogenic

synthesis

Reaction

+ 2 NAD⁺ + 2 reduced ferredoxin [iron-sulfur] cluster =

+ 2 NADH + 2 oxidized ferredoxin [iron-sulfur] cluster

Synonyms

BCD, Bcd/electron-transfer flavoprotein complex, Bcd/EtfAB, BcdA-EtfBC, Bct/Etf complex, bifurcating butanoyl-CoA dehydrogenase, bifurcating butyryl coenzyme A dehydrogenase/electron-transferring flavoprotein complex, bifurcating butyryl-CoA dehydrogenase, butanoyl-CoA dehydrogenase (NAD+, ferredoxin), butanoyl-CoA dehydrogenase/Etf complex, butyryl coenzyme A dehydrogenase, butyryl-CoA dehydrogenase, butyryl-CoA dehydrogenase-EtfAB complex, butyryl-CoA dehydrogenase/electron transferring flavoprotein complex, butyryl-CoA dehydrogenase/Etf complex, butyryl-coenzyme A dehydrogenase-EtfAB complex, electron transferring flavoprotein/butyryl-CoA dehydrogenase, Etf-Bcd complex, Etf-butyryl-CoA dehydrogenase complex, EtfAB/Bcd

ECTree

1 Oxidoreductases

1.3 Acting on the CH-CH group of donors

1.3.1 With NAD⁺ or NADP⁺ as acceptor

1.3.1.109 butanoyl-CoA dehydrogenase complex (NAD+, ferredoxin)

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1	AA Sequence
2	Application
3	Cloned(Commentary)
8	Cofactor
2	Crystallization (Commentary)
4	General Information
1	General Stability
1	kcat/KM [mM/s]
2	KM Value [mM]
3	Localization
13	Molecular Weight [Da]
12	Natural Substrates/ Products (Substrates)
16	Organism
2	Oxidation Stability
11	Pathway
2	pH Optimum
6	Protein Variants
4	Purification (Commentary)
1	Reaction
14	Reference
1	Storage Stability
19	Substrates and Products (Substrate)
7	Subunits
30	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Turnover Number [1/s]

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Reference on EC 1.3.1.109 - butanoyl-CoA dehydrogenase complex (NAD+, ferredoxin)

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687430

Li, F.; Hinderberger, J.; Seedorf, H.; Zhang, J.; Buckel, W.; Thauer, R.K.

Coupled ferredoxin and crotonyl coenzyme A (CoA) reduction with NADH catalyzed by the butyryl-CoA dehydrogenase/Etf complex from Clostridium kluyveri

J. Bacteriol.

190

843-850

2008

Clostridium kluyveri

17993531

725287

Aboulnaga, e.l.-.H.; Pinkenburg, O.; Schiffels, J.; El-Refai, A.; Buckel, W.; Selmer, T.

Effect of an Oxygen-Tolerant Bifurcating Butyryl Coenzyme A Dehydrogenase/Electron-Transferring Flavoprotein Complex from Clostridium difficile on Butyrate Production in Escherichia coli

J. Bacteriol.

195

3704-3713

2013

Clostridioides difficile (Q18AQ1 and Q18AQ6 and Q18AQ5), Clostridioides difficile, Clostridioides difficile DSM 1296T (Q18AQ1 and Q18AQ6 and Q18AQ5)

23772070

731998

Wang, S.; Huang, H.; Moll, J.; Thauer, R.K.

NADP+ reduction with reduced ferredoxin and NADP+ reduction with NADH are coupled via an electron-bifurcating enzyme complex in Clostridium kluyveri

J. Bacteriol.

192

5115-5123

2010

Clostridium kluyveri, Clostridium kluyveri DSM 555

20675474

732165

Chowdhury, N.P.; Mowafy, A.M.; Demmer, J.K.; Upadhyay, V.; Koelzer, S.; Jayamani, E.; Kahnt, J.; Hornung, M.; Demmer, U.; Ermler, U.; Buckel, W.

Studies on the mechanism of electron bifurcation catalyzed by electron transferring flavoprotein (Etf) and butyryl-CoA dehydrogenase (Bcd) of Acidaminococcus fermentans

J. Biol. Chem.

289

5145-5157

2013

Acidaminococcus fermentans (D2RIQ2 and D2RIQ3 and D2RL84), Acidaminococcus fermentans DSM 20731 (D2RIQ2 and D2RIQ3 and D2RL84)

24379410

733386

Buckel, W.; Thauer, R.K.

Energy conservation via electron bifurcating ferredoxin reduction and proton/Na+ translocating ferredoxin oxidation

Biochim. Biophys. Acta

1827

94-113

2013

Clostridium kluyveri, Clostridium tetanomorphum

22800682

734071

Mueller, N.; Schleheck, D.; Schink, B.

Involvement of NADH:acceptor oxidoreductase and butyryl coenzyme A dehydrogenase in reversed electron transport during syntrophic butyrate oxidation by Syntrophomonas wolfei

J. Bacteriol.

191

6167-6177

2009

Syntrophomonas wolfei

19648244

741631

Berzin, V.; Tyurin, M.; Kiriukhin, M.

Selective n-Butanol production by Clostridium sp. MTButOH1365 during continuous synthesis gas fermentation due to expression of synthetic thiolase, 3-hydroxy butyryl-CoA dehydrogenase, crotonase, butyryl-CoA dehydrogenase, butyraldehyde dehydrogenase, and NAD-dependent butanol dehydrogenase

Appl. Biochem. Biotechnol.

169

950-959

2013

Clostridium ljungdahlii, Clostridium ljungdahlii DSM 13528

23292245

765454

Demmer, J.K.; Pal Chowdhury, N.; Selmer, T.; Ermler, U.; Buckel, W.

The semiquinone swing in the bifurcating electron transferring flavoprotein/butyryl-CoA dehydrogenase complex from Clostridium difficile

Nat. Commun.

1577

2017

Clostridioides difficile (A0A125V4E7), Clostridioides difficile, Clostridioides difficile DSM 1296 (A0A125V4E7)

29146947