1.2.1.72: erythrose-4-phosphate dehydrogenase
This is an abbreviated version!
For detailed information about erythrose-4-phosphate dehydrogenase, go to the full flat file.
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Synonyms
E4P dehydrogenase, E4PD, E4PDH, epd, Epd dehydrogenase, erythrose 4-phosphate dehydrogenase, gap2, GapB, gapB-encoded dehydrogenase, GapB-encoded protein
ECTree
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Systematic Name
Systematic Name on EC 1.2.1.72 - erythrose-4-phosphate dehydrogenase
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D-erythrose 4-phosphate:NAD+ oxidoreductase
This enzyme was originally thought to be a glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12), but this has since been disproved, as glyceraldehyde 3-phosphate is not a substrate [1,2]. Forms part of the pyridoxal-5'-phosphate coenzyme biosynthesis pathway in Escherichia coli, along with EC 1.1.1.290 (4-phosphoerythronate dehydrogenase), EC 2.6.1.52 (phosphoserine transaminase), EC 1.1.1.262 (4-hydroxythreonine-4-phosphate dehydrogenase), EC 2.6.99.2 (pyridoxine 5'-phosphate synthase) and EC 1.4.3.5 (pyridoxamine-phosphate oxidase).