1.2.1.42: hexadecanal dehydrogenase (acylating)
This is an abbreviated version!
For detailed information about hexadecanal dehydrogenase (acylating), go to the full flat file.
Word Map on EC 1.2.1.42
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1.2.1.42
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acyl-coas
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photobacterium
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harveyi
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phosphoreum
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fischeri
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tetradecanoic
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marinobacter
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luxcde
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1-hexadecanol
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luxab
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leiognathi
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luciferase-catalyzed
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jojoba
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acyl-protein
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aquaeolei
- 1.2.1.42
- acyl-coas
- photobacterium
- harveyi
- phosphoreum
- fischeri
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tetradecanoic
- marinobacter
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luxcde
- 1-hexadecanol
- luxab
- leiognathi
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luciferase-catalyzed
- jojoba
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acyl-protein
- aquaeolei
Reaction
Synonyms
ACIAD3383, Acr1, AtFAR2, CoA-acylating aldehyde dehydrogenase, coenzyme A-acylating aldehyde dehydrogenase, dehydrogenase, hexadecanal (acylating), FACoAR, FAR, FAR1, FAR2, FAR6, fatty acid reductase, fatty acyl-CoA reductase, MS2, PduP
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 1.2.1.42 - hexadecanal dehydrogenase (acylating)
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REACTION DIAGRAM
a fatty acyl-CoA + 2 NADPH + 2 H+
a fatty aldehyde + CoA + 2 NADP+
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?
arachidonoyl-CoA + NADPH + H+
arachidonic aldehyde + CoA + NADP+
Marinobacter nauticus
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86% activity compared to hexadecanoyl-CoA
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-
?
cis-11-hexadecenal + CoA + NADP+
(E)-hexadec-11-enoyl-CoA + NADPh + H+
Marinobacter nauticus
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-
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?
dodecanoyl-CoA + NADPH + H+
dodecanal + CoA + NADP+
Marinobacter nauticus
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26% activity compared to hexadecanoyl-CoA
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-
?
octanoyl-CoA + NADPH + H+
octanal + CoA + NADP+
Marinobacter nauticus
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9% activity compared to hexadecanoyl-CoA
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-
?
oleoyl-CoA + NADPH + H+
oleic aldehyde + CoA + NADP+
Marinobacter nauticus
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78% activity compared to hexadecanoyl-CoA
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-
?
palmitoleoyl-CoA + NADPH + H+
palmitoleic aldehyde + CoA + NADP+
Marinobacter nauticus
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99% activity compared to hexadecanoyl-CoA
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-
?
[hexadecanoyl]-acyl carrier protein + NADPH + H+
?
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preferred substrate
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-
?
2-methyl-1-hexadecanal + CoA + NADP+
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?
2-methyl-1-hexadecanoyl-CoA + NADPH + H+
2-methyl-1-hexadecanal + CoA + NADP+
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?
2-methyl-1-hexadecanoyl-CoA + NADPH + H+
2-methyl-1-hexadecanal + CoA + NADP+
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?
1-hexadecanal + CoA + NADP+
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preferred substrate
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-
?
hexadecanoyl-CoA + NADPH + H+
1-hexadecanal + CoA + NADP+
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preferred substrate
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-
?
hexadecanoyl-CoA + NADPH + H+
1-hexadecanal + CoA + NADP+
Marinobacter nauticus
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100% activity
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-
?
hexadecanoyl-CoA + NADPH + H+
1-hexadecanal + CoA + NADP+
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preferred substrate
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-
?
hexadecanal + CoA + NADP+
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preferred substrate
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?
hexadecanoyl-CoA + NADPH + H+
hexadecanal + CoA + NADP+
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24% conversion efficiency
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?
octadecanal + CoA + NADP+
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low activity
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-
?
octadecanoyl-CoA + NADPH + H+
octadecanal + CoA + NADP+
Marinobacter nauticus
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69% activity compared to hexadecanoyl-CoA
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-
?
tetradecanal + CoA + NADP+
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preferred substrate, 34% conversion efficiency
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-
?
tetradecanoyl-CoA + NADPH + H+
tetradecanal + CoA + NADP+
Marinobacter nauticus
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60% activity compared to hexadecanoyl-CoA
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?
?
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the enzyme is highly active with hexadecanoyl-CoA and shows lower activity with tetradecanoyl-CoA or octadecanoyl-CoA
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?
additional information
?
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no products are detected when using C18:1-CoA, 2-methyl-16:0-CoA, 2-methyl-18:0-CoA or C16:0 free fatty acid as substrates
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?
additional information
?
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the enzyme is highly active with hexadecanoyl-CoA and shows lower activity with tetradecanoyl-CoA or octadecanoyl-CoA
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?
additional information
?
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Marinobacter nauticus
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the enzyme exhibits no detectable reduction with free fatty acids, less than 1% activity with acetaldehyde and propanal
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?