>P33247|squalene-hopene cyclase|EC 5.4.99.17|Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / BCRC 14685 / JCM 5260 / KCTC 1825 / NBRC 15652 / NCIMB 11725 / NRRL B-14509 / 104-IA)|Swiss-Prot
MAEQLVEAPAYARTLDRAVEYLLSCQKDEGYWWGPLLSNVTMEAEYVLLCHILDRVDRDR
MEKIRRYLLHEQREDGTWALYPGGPPDLDTTIEAYVALKYIGMSRDEEPMQKALRFIQSQ
GGIESSRVFTRMWLALVGEYPWEKVPMVPPEIMFLGKRMPLNIYEFGSWARATVVALSIV
MSRQPVFPLPERARVPELYETDVPPRRRGAKGGGGWIFDALDRALHGYQKLSVHPFRRAA
EIRALDWLLERQAGDGSWGGIQPPWFYALIALKILDMTQHPAFIKGWEGLELYGVELDYG
GWMFQASISPVWDTGLAVLALRAAGLPADHDRLVKAGEWLLDRQITVPGDWAVKRPNLKP
GGFAFQFDNVYYPDVDDTAVVVWALNTLRLPDERRRRDAMTKGFRWIVGMQSSNGGWGAY
DVDNTSDLPNHIPFCDFGEVTDPPSEDVTAHVLECFGSFGYDDAWKVIRRAVEYLKREQK
PDGSWFGRWGVNYLYGTGAVVSALKAVGIDTREPYIQKALDWVEQHQNPDGGWGEDCRSY
EDPAYAGKGASTPSQTAWALMALIAGGRAESEAARRGVQYLVETQRPDGGWDEPYYTGTG
FPGDFYLGYTMYRHVFPTLALGRYKQAIERR
>B6K412|squalene-hopene cyclase|EC 5.4.99.17|Schizosaccharomyces japonicus (strain yFS275 / FY16936)|Swiss-Prot
MKTDGNTTLDTTISMEELERTVKSAYEALAKDQQDDGHWIYELEADVTIPAQFILLEHTL
DKIDEELEQKIANYLRRCQSREHWGWPVYYGGEFNISASVQAYFALKMTGEDINAPHMVR
AREAILAHGGPEYANVFTRIQLSLFGEASWLATPFMPVEIMLLPRWMYFSIWNMSYWSRT
TVAPLLIVADLKPKAINPRNVHIPELFPTPPDKVKTWIHGPFRSKWGHVFKFIDTAIRPF
TRFVPSFLHKKAYKAALDFIEPRLNGVDGLGAIYPPMSYSAVMYRALGIPDDDPRAATNW
EALKGLLVIKEREAYCQACVSPVWDTALSGHALMEASFGPDGINADRTEKLIDRAAHWLR
AHQVLNVVGDWAINNPNLQPGGWAFQYGNDYYPDVDDTAVAAMLLHRQNLPENEEALDRA
RKWIIGMQSSNGGWGAFDIDNDKQILNDIPFADHGALLDPPTADVSARCISLLAELGHPE
DRPVIERGIKYLRKEQEEDGSWFGRWGTNYIYGAWSVLCAFNASGVPHDDPSVLKCVNFL
KSVQREDGGWGESCETYEGSAHGVYTESLPSQTAWAVLGLMASGRRTDPAVKRGIVWLIQ
HQQDNGEWAEEPFNAVGFPRMFYLHYLGYKQFFPLLALARYRHMEKSGTNNVSFAF
>P54924|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)|Swiss-Prot
MDSVNATAREAKESKISESEILESSIASATQGVLGFQQSDGHWVFELEADCTIPAEYVLL
RHYLAEPVDTVLEAKIGNYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDSIDAP
HMVRAREAIHARGGAIHSNVFTRFMLAMFGIVTWRAVPVLPIEIMLLPFWSPFHINKISY
WARTTMVPLMVIAALKPRAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFLLFRSLDA
ILRVIEPLFPKSLRKRAIDTALAFSEERLNGEDGMGAIYPPMANLVMMYDALGKDENYPP
RAVTRRGIDKLLVIGDDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKHGLDWLIPK
QELEVKGDWAVKRPDVRPGGWAFQYNNAYYPDLDDTAVVVMSMDRMRREHGVTGYDSAID
RGREWIEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCVSMLAQLGE
TAKTSKHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVRHDDPMIRKAA
DWLASIQNKDGGWGEDAVSYRLDYKGWEAAPSTASQTAWALLALMAAGEVDHPAVARGVE
YLIATQNEKGLWDEQRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRNTNSRVVGVGM
>P55348|squalene-hopene cyclase|EC 5.4.99.17|Sinorhizobium fredii (strain NBRC 101917 / NGR234)|Swiss-Prot
MNKHSGNRTAIDPAALEMSIASATEALLAYRHADGHWAFELEADSTIPSEYILLRHYLAE
PIDVVLEAKIGNYLRRTQGAHGGWPLVHDGPFDMSASVKSYFALKMIGDSVDAAHMVKAR
EAIRARGGAANSNVLTRFLLALYGVVSWRAVPVLPIEIVLLPIWSPFHLYKISYWARTTI
VPLMVLAVLKPRAKNPKGVGIEELFLQDTKSVGMNPKAPHQSWGWFLLFRGIDGILRVIE
PHLPKKLRERAIASALAFTEERLNGEDGMGAIYPSMANIVMMYDALGKDDHFPPRAIARR
AIDKLLVIGEEEAYCQPCLSPVWDTALTCHALQEVGGANAVAKAKQGLDWLKPRQVLDVK
GDWAVKAPNIRPGGWPFQYNNAHYPDLDDTAVVVMAMDRAQRHAGSKEYATAIARGREWI
EGMQSRDGGWAAFDVNNLEYYLNNLPFADHGALLDPPTEDVTARCVSMLAQVGEFTQRSK
AVAEGIAYLRRTQHAEGSWYGRWGLNYIYGTWSVLCALNAAGIDHQDPMIRKAVEWLVSI
QSWDGGWGEDAISYRLDYSGYEQAPSTSSQTAWALLGLMAAGEVEHPAVARGVNYLKNAQ
TENGLWDEQRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNV
>P33990|squalene-hopene cyclase|EC 5.4.99.17|Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)|Swiss-Prot
MTVSTSSAFHHSPLSDDVEPIIQKATRALLEKQHQDGHWVFELEADATIPAEYILLKHYL
GEPQDLEIEAKIGRYLRRIQGEHGGWSLFYGGDLDLSATVKAYFALKMIGDSPDAPHMLR
ARNEILARGGAMRANVFTRIQLALFGAMSWEHVPQMPVELMLMPEWFPVHINKMAYWART
VLVPLLVLQALKPVARNRRGILVDELFVPDVLPTLQESGDPIWRRFFSALDKVLHKVEPY
WPKNMRAKAIHSCVHFVTERLNGEDGLGAIYPAIANSVMMYDALGYPENHPERAIARRAV
EKLMVLDGTEDQGDKEVYCQPCLSPIWDTALVAHAMLEVGGDEAEKSAISALSWLKPQQI
LDVKGDWAWRRPDLRPGGWAFQYRNDYYPDVDDTAVVTMAMDRAAKLSDLRDDFEESKAR
AMEWTIGMQSDNGGWGAFDANNSYTYLNNIPFADHGALLDPPTVDVSARCVSMMAQAGIS
ITDPKMKAAVDYLLKEQEEDGSWFGRWGVNYIYGTWSALCALNVAALPHDHLAIQKAVAW
LKTIQNEDGGWGENCDSYALDYSGYEPMDSTASQTAWALLGLMAVGEANSEAVTKGINWL
AQNQDEEGLWKEDYYSGGGFPRVFYLRYHGYSKYFPLWALARYRNLKKANQPIVHYGM
>A0A8F6EY64|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces albidoflavus|TrEMBL
MTATTNGPAGAAPSRPAPARTTAATTDTAALDGAAVEAAAERARARAADHLLGLQSPEGW
WKGDLDTNVTMDAEDLLLRQFLGIRDEATTRSAALFIRGEQREDGTWATFHGGPPDLSTT
VEAYVALRLAGDSPDAPHMTRAAHWVRSQGGIAEARVFTRIWLALFGWWPWDRLPELPPE
LIFLPPWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPADPAPRARFAP
LASWNGAFQRLDRALHAYRKVAPRALRRAAMATAGRWIVERQENDGCWGGIQPPAVYSMI
ALHLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALADAGVPAD
HPQLVRAADWMLDEQIERPGDWSVRRPHLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVR
HPDTARMERAISLGVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDPPSADVT
AHVVEMLAAEGLAADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALVDAGLP
TTHPAIRRAVAWLESVQNDDGGWGEDLRSYREQGRMARGASTASQTGWALMALLAAGERE
SRAARRGVTFLAKTQHEDGSWEEPYYTGTGFPWDFSINYHLYRQVFPLTALGRYTRGAAP
EGA
>A0A6B0W8Z1|squalene-hopene cyclase|EC 5.4.99.17|Holophagales bacterium|TrEMBL
MAGLTRGLHERPESSPTPPPASDRARTAQRRAATSRPRPAKVIDLTIDAAVRNLLGQRRD
DGHWCAELEGDTILESEYVLLLHFLGRGDDPRVAACCERLRGQQQQGGGWAIYPDGPTDP
SVSVKAYLCLKLAGDDPQSPRMADARRAILRAGGLRACNSYTRLYLSIFGLWTWRRSPAV
PPELILLPRWFYFNLHEMSSWTRTIVVPLSVIWALKPSVPLDVALDELQGASPRGRRRTT
LYESFWSRVFAGVNGLIKLVEVIGPVPGWRRPALKKAEEWLVAHVEGSDGLGAIFPAMVN
AVIAFRCLGYEESHPLVQGQLRELERFEIEEAGEMRLQPCLSPVWDTALSVGALLAADMD
GNDAPIREAVEWLLEREVTVAGDWREKSLQDASGGWCFEYRNDHYPDCDDTAEVLLVLAA
VRDRAGELEARKQAAAARGKRWLLGLQNPDGGWASFDRCCDKEVLTLIPFADHNAMIDPS
TPDITARVISALLAHGHDPGDGPVRRATDYLLREQEKDGSWPGRWGANGIYGTWLALSAL
APLAARPGGRAGERLSRACRLGRRWLLAVQNEDGGWGESLRSYDDPAFRGRGRSTASQTA
WAMMGLIASLESRPWSDDAARTVTALDRAVAFLQERQRDDGSWYDRDWTGVGFPGVFYLR
YHGYAQYFPLEALAAYRRLAVPEPDAMPANGPF
>A0A1S0SL57|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia pseudomallei|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGAVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A6B1C2Z1|squalene-hopene cyclase|EC 5.4.99.17|Acidimicrobiia bacterium|TrEMBL
MGVEQCLARARDRLMSLQDIEGWWKDELETNVSIEAEDLFLREFLGIADPEVTRQTANWI
RHSQRADGTWATFYQGPADLSVTVEAYWALRYAGDPVDADHMTKAADYIRSEGGLERSRV
FTRIWMALFGLWRWEDLPALPPEVILLPKQVPLNIYDFACWARQTVVSLTVVGAHRPVRS
MGINLDEIRTGATPPERELAPPGTVARRFQRLDQALHHYENRPHRRLREWSLRRAEQWII
ARQEADGCWGGIQPPWVYSLLALYVRGYSLHHPILAQGLAGFDAWTIVEDDMRRLECCQS
PVWDTCLALIALADAGVDPDDSQMEAGARWLMDQEVQVVGDWAEQRPHLAPGGWAFEFEN
NFYPDLDDTAEVALALRRINHTDARKVNRALDRAVEWVQGMQCQDGGWAAFDADNCSPLV
AELPFCDFGEVIDPPSADVTAHVIEMLCELDGDGQGLRVDREVVDRGLKWLSDEQEDDGS
WYGRWGANYIYGTGAAIPALISAGIPTDDDRVVRACKWLESVQNNDGGWGEDMRSYTNRE
WRGRGESTPSQTAWALLALVAAGRASEETTRRGVAWLVENQRRDGDWDEPWYTGTGFSGD
FYIRYHLYRLVFPVMALGRWVRAIEDEA
>Q0B2H5|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia ambifaria (strain ATCC BAA-244 / AMMD)|TrEMBL
MIRRMNKSGPSPWSALDAAIARGRDALMRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDARQEKMARYLRAIQRLDTHGGWDLYVDGDPDVSCSVKAYFALKAAGDSEHAPHMVRA
RDAILELGGAARSNVFTRILLATFGQVPWRATPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNIAIPELFVTPPDQERQYFPPARGMRRAFLALDRVVRHVEPL
LPKRLRQRAIRHAQAWCAERMNGEDGLGGIFPPIVYSYQMMDVLGYPDDHPLRRDCENAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVAVPEAGAPASALDELDARIARAY
DWLAERQVNDLRGDWIENAPADTQPGGWAFQYANPYYPDIDDSAVVTAMLDRRGRTHRNA
DGSHPYAARVARALDWMRGLQSRNGGFAAFDADCDRLYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRADDRASLARAIDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALAGED
PSQPYIARALAWLRARQHADGGWGETNDSYIDPALAGTNAGESTSNCTAWALLAQMAFGD
GESESVRRGIAYLQSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GGVSAAGAHAVPASTGADAALA
>R9W211|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAQAVFPLGDTGVAANDPRMEKAADWILAKEVRTKGDWAMKVSNAEPGGWYFEFN
NEFYPDVDDTAQVLLALKAVDNPRERYQHDVCERAIDWLFAMQCRNGGWASFDKDNTKMI
FQYVPFADHNAMLDPPTVDITGRILEMLAAYGYTQRDKRVEKAMQFMLENQEPDGSWFGR
WGVNYLYGTFLVLRGLEAQGVWNHEPPIQHAAEWIRMVQNADGGWGE
>R9W2P4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAQAVFAPGGASVPRDDPRLQKAADWMLSKEVRHKGDWAMKVPKTEAGGWYFEFN
NEFYPDVDDTAQVLLALNKVDNPRERYQHQVAERAIDWEFAMQCRNGGWGSFDKDNTKMI
FQYVPFADHNAMLDPPTVDITGRILEMLASYGYARGDKRVEKAIKFIFEEQEPDGSWFGR
WGVNYIYGTFLVLRGLDAIGVCRHEPQIQQGAEWIRMVQNADGGWGE
>A0A3N8YNA9|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cenocepacia|TrEMBL
MNDLTEMATLSAGAVPADVDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKALDKLLVVHDDEAYCQPCLSPVWDTSLVAHALLETGDARAQEAVLRGLEWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLTESDTYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRAAQWL
LSIQNKDGGWGEDGDSYKLNYRGYEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLV
AQQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A498DZ86|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. Z26|TrEMBL
MTATADGSTGAVQPGVRTGGGPVAPAPTAPAIPAAAPAGDSATTPAGDPRVTDPRALAER
ANARAVAHLLALQHEEGWWKGDLETNVTMDAEDLLLREFLGVRDAHTTGAAARHVRSRQR
ADGTWGTFHGGPGDLSTTVEAYVALRLAGDAPEAPHMRAAAGWVRAHGGIAGTRVFTRVW
LALFGWWRWTDLPELPPEIIWLPKWFPLNLHDFGCWARQTIVPLTVVSAYRPVRPAPFGL
DELHRDPARPNPVRAKAPAYTWDGAFQRLDGALHAYRGVALRGLRRAALRDASRWIVERQ
ENDGCWGGIQPPAVYSLIALRLLGYDLDHPVLRAGLESLDRFAVWREETADEPGGGPAGA
PVRMVEACQSPVWDTCLATVALTDAGLPADHPALTRAADWMLGEQVVRPGDWAVRRPQLP
PGGWAFEFHNANYPDIDDTAEVVLALHRVRHADPERVDRVVRRAVRWTLGMQSANGGWGA
FDADNTSELPDRLPFCDFGEVVDPPSADVTAHVVEMLSRAGHRDHPANRRAVAWLLAQQE
PGGAWFGRWGVNYLYGTGAVVPALVDAGLPATHPALRRAVDWLVDVQNEDGGWGEDLRSY
RDPDWAGRGASTPSQTAWALLALLAAGERDGDAVRRGVAHLAGTQRADGTWDEPWFTGTG
FPWDFSINYHLYRLVFPVTALGRYLHGGTGTSDGTGDGTTTGTDERDGRAR
>A0A3M2AU29|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
MDLLKNLLERLSDSLFSSGPGERPSTSSKRRPPPLKLVSHNPHPTVALETSPSKVAHAVG
GHAEALDEALTKSGAWQLAQQNPHQGYWVYELEADTTLTSEYLMLRRFLGVRDHERERKA
VEYLRMTQLPEGGWPIYAGGPAEISASVKAYFALKLAGVDSQDPDLQKARNAILAMGGVV
ASNVFTKITLALFDQYDWQGIPSMPAEIILAPTRFYFNLYTVSYWSRAVIIPLLIVFAHR
PVCQIPPEQGIEELYCQPRSSIRYRDNPPFQKDSAWFSWRNFFVWVDRVLKVYERYPIRT
AREKALKKAETWMVDHMRGEGGLGAIYPAMANSIFALWALGYPADHPLMQKALREIEALE
IEVPGSSDGRRPATLHLQPCHSPVWDTALTINAFVEQGYPLSHPALQRAQTWLRSRQTRS
VGDWIMSSPNAQPGGWYFQFENEWYPDVDDTAAVVMALAKLSPVHPADTYDEAIRRGKEW
VLAMQGSDGGWGAYDKDNNRLIFNKIPFADHQALLDPSTADLTGRCLEMLGTLGYDRSHP
AVRPAVEFLRRVQEPNGSWYGRWGVNYIYGTWCVLSGLRAIGEDMSAPWIKKAVAWLESV
QNVDGGWGESCLSYADPAWAGKGQSTPSQTAWALMALLAAGVSDSLSVVRGVNFLLRHQQ
DNGTWYEPFHTGTGFPRVFYLRYWGYSQYFPFWALAMYRNMKTKGQTRADELRQVARAKR
KTTSP
>A0A5B8UCK4|squalene-hopene cyclase|EC 5.4.99.17|Baekduia soli|TrEMBL
MSGAAVAHVDPRTALVRGVERLRDLQDDAGWWKGALDTNVTMDAEDLLMRAFLGILDPGQ
TSAAARWIRGQQREDGTWANFHGGPGDLSTTAEAYVALRLAGDGPDEEHMRTAAAFVRAG
GGLEATRVFTRIWMSLFGLWSWDDVPALSPEVMLLPSWMPLNLYDFACWARQTIAPLTII
GAYRPVRPLPFGIDELRSGDGAPRPRRSLRDWPGRLAWLDAALHRYERRPLGPLRRLALD
RAERWIVERQEADGSWGGIQPPWVYSLMALNVRGYAIDHPVMAAGLAGLDAFTLHEDGER
RIEACQSPVWDTALAVVALADAGVEADDDAMTRAAAWLRDEAVAVPGDWCVRRPELAPGG
WAFEFANDHYPDVDDTAEVVMALRRAGVDAGPEIRRGVEWTIGMQCADGGWAAFDADNTR
RLCTELPFCDFGEVIDPPSADVTAHVVEMLALEGRDEVAMRRGIVWLRDAQEDDGSWFGR
WGINHVYGTGAVLPALAAAGVSPLDPAVRRAVAWLRAHQNVDGGWGEDPRSYEDPAWVGR
GASTASQTAWALLALHAAGEGSGEAAERGLRWLAATQLPDGSWDEPEYTGTGFPGDFYIN
YGLYRQVFPVMALARCLR
>A0A4S1CCF3|squalene-hopene cyclase|EC 5.4.99.17|Geomonas terrae|TrEMBL
MNAPFKHPISHALTSFNGIVSEPEQTAEQKAGATVHQFPASLWKSKPGKAKSPLDVAIEG
CRDFFFREQLPKGYWWAELESNVTITAEYIMLFHFLGLVDRERERKMSAYLLSKQTEEGS
WTIYFGGPGDLSTTIEAYFALKLAGYPADHPAMEKARAFVLEKGGIIKARVFTKIFLALF
GEFDWLGVPSMPVELNMLPNWAYINMYEFSSWARATIIPLSIVMHHRPVHGIDPSQRVQE
LFVRPPRAIDYSFTKEEGILTLKNFFIGLDHVLKVYERSPIRPFRKAGIAKAEEWILEHQ
EETGDWGGIQPAMLNAVLALSALGYENDHPVMVQGLKALDNFCIENDDQIVLQSCISPVW
DTALALKALVDAGVPTDHPSLVKGAQWLLEREVRRPGDWRIKSPELEPGGWAFEFQNDWY
PDVDDSGFVMMALKDIKVKDPKALEESVRRGIAWCLGMQSKNGGWGAFDKDNTKHFLNKI
PFADLEALIDPPTADLTGRMLELMGSFGYPKSYPAAVRGLDFLKKNQEPEGPWWGRWGVN
YLYGTWSVLCGLSAIGEDMEAPYVKKAVNWIKSRQNIDGGWGETCESYHDPSLAGMGEST
ASQTGWALLGLMATGEVNCATVVRGIQYLISTQNPDGTWDETQYTGTGFPKYFMIKYHIY
RNCFPLMALGTYRTLTGGLSEE
>A0A7K2QYA9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5471|TrEMBL
MTATTDGSTGALPPRAPSAGDATAETTENDPAAPTSTAAAARRATARATDYLLSVQDAAG
WWKGDLETNVTMDAEDLLLRQFLGIGDPRTTEAAARHIRGEQRDDGTWATFYGGPGELSA
TIEAYVALRLAGDEPDAAHMARAAAWIREHGGVAAARVFTRIWLALFGWWKWEDLPELPP
ELIWFPKWFPLNIYDFACWARQTIVALTIVCSVRPVRPAPFALDELHADPARPNPPRPLA
PPTTWDGVFQRLDKGLHLYRKVAVRKLRRSALRAAASWIVERQENDGCWGGIQPPAVYSI
MALHLLGYDLGHPVLRQGLESLDRFAVWREDADGAPVRMIEACQSPVWDTCLAAIALADA
GLPADHPQLVKAADWMLAEQIRRPGDWSVRRPRLPSGGWAFEFENDNYPDIDDTAEVVLA
LRRIQHPDPERVDAAVQRAVRWNLGMQSKNGAWGAFDADNTSPFPNRLPFCDFGEVIDPP
SADVTAHVVEMAADLGMTHDARVRRGIRWLLAEQEPDGSWFGRWGTNYIYGTGSVLPALA
AAGIPASHPAVRRAVRWLERVQNEDGGWGEDQRSYHDKAWAGRGESTASQTAWALMALLA
AGERESAAVARGVRWLAGTQRDDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYV
NGGPAGASQGA
>A0A7V0KJR8|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Acetothermia bacterium|TrEMBL
VYSLIALYVLGHDPEGPILKKGIEGLKRYSIEEEGKFRFQSCISPVWDTGLAMIALQDAG
LPADHPALVKAGKWLLNEQIFVGGDWQVKCNGRPGGWAFEFDNDVYPDTDDSSVVMMALL
RTDLPERAKEFAISRGLEWLLAMQSSNGGWGAFDRNNTRALLREIPFADFGEMIDPPSVD
VTAHIVELLGRLGYKKGFRPLDRALAYLKREQESDGAWYGRWGVNLTYGIGYVLPALAAV
GEDMRAPYVRRAVEWLIEHQNEDGGWGERVEGYYDPKWRGRGPSTASQTAWALLGLLAAG
EVDHPATRRGVEYLIETQQEDGGWDEPYFTGTGFPTDFMINYHLYRDNFPMMALGRYREA
RRGDGEARG
>A0A7C4JJK0|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Acetothermia bacterium|TrEMBL
RQEADGCWGGIQPPWVYSLLALYALGHAPESPVLARGIAGFARYAIEDERGFRLQSCISP
VWDTGLATLALQDAGLPPDHPALVRAGNWLLSQQIFVGGDWQVRCRARPGGWAFEFDNDR
YPDTDDTAVVMMALQGIALPEKAKKFALERGLEWLLGMQSKNGGWGAFDRDNTKSFLREI
PFADFGELLDPPSADVTGHVVELLGRLGYRRGFRPLDRALRYLLREQEEDGSWYGRWGVN
HLYGTGAVLPALRAIDFPMDDPRVRRAVDFLLSRQNPDGGWGEDVLSYHKKELRGRGPST
ASQTAWALLALLAAGEARSEAVRRGIAYLVAAQRPDGTWDEPYFTGTGFPTDFMIRYHLY
RHYFPLMALGRYRRALEER
>A0A7V0I7Y5|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Acetothermia bacterium|TrEMBL
MVESSPGPPYHRDQLPSSFCHSRSWRAVDWLLKRQSPEGWWWAELESNATITAEHLFLTH
ILGIGSQELWDEIARQLLEWQNEDGSWSLWYGGPGELSTTVEAYVALKMAGVDPDSPEMR
RAREWILRRGGIERARNFTKIWLALLGEWPWEGLPVIPPEVVLLPRWFPINIYKFASWAR
GTMVPLTIVYAYRPTFPIPKHARIDELFPRGRANADLSLPRKRSAWGRFFTFADKVLRVH
EHSRWKPLRKRAIKAAEEWIIARQEADGCWGGIQPAWVYSLIALYVLGHDPEGPILKKGI
EGLRRYSIEEEGKFRFQSCISPVWDTALAMIGLQDAGLPRDHPALVKAGKWLLNEQIFVG
GDWQVKCKARPGGWAFEFDNDVYPDTDDTAVVLMAILGTDLPKRAKDFALSRGLEWLLGM
QSRNGGWGAFDRDNTAAFLREIPFADFGEMIDPPSVDVTAHVVEFLGKMGYRPGFKPLDR
ALSYIFREQEPDGPWYGRWGVNYIYGTGYVLPALEAVGFPMDDPRVRKAVDWLLSRQNED
GGWGEDVMSYHRRELRGRGPSTASQTAWALLALIAAGGARSEAVKRGIEYLIRTQNDEGT
WNEPYFTGTGFPTDFMIRYHLYRHHFPLMALGRYRKAVMGDE
>A0A538CDL1|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MRTASRIRVAAEDALRRARDHLLKLQHEQGWWKGELETNVTMDAEDLLLRQFLGIRGEEE
TRLAANWIRSKQRDDGTWTNFFGGPADLSTTIESYVALRLADDPRDAAHMRRALEYIRDR
GGLEGARVFTHMWLALFGAWSWDEIPALPPEVIFLPDWFPLNIYDFACWARQTIVALTVV
GAHRPIRPLGFGVEELRTGAPGAALDPWTTWAGGFQRLDRALHWYERHPSGRLRRLALAR
ATEWIVRHQEADGSWGGIQPPWVYSLIALNLRGYGLDHPVMRGGLDGIDRFTIVEGETRR
LEACQSPVWDTALAVIALADAGLGADDPAMLRAVDWLLREEIRVRGDWAVRRPNLPPGGW
AFEFANDNYPDIDDTAEVVLALRRVARDHPEPDRVEAAIARGLAWLVGMQSADGGWAAFD
ADNTRTLCRELPFCDFGEVIDPPSADVTAHVVEMLAAEGMGGERPTRRGLSWLARHQERG
GSWFGRWGANHVYGTGAVLPAAVAAGIPRENPKIRAGVRWLERHQNHDGGWGEDLRSYDE
AAWIGRGASTASQTAWALLALLAAGERESEAARRGVAWLAQNQRAEGTWDEPWYTGTGFP
GDFYINYHLYRLVFPITALGRYLGGTT
>A0A538IDC9|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
PPSSPFSIYDFSCWARQTFVALAVAQSLRPVRPADVDLTAIGAIPGRTRRPRRPSLLRRR
ALTVAERWIRERQDADGSWGGIQPPWVWGIIALAALGHGLDDPVLGKAVEGWRGFMVEDG
ERLRPEACQSPVWDTGLALLALRACGVADDHPQLVRAGEYLLSEEVRVKGDWAIRKPDLA
PGGWAFEYENDNYPDVDDTAVLPLALQGMGIGEEAAIARGVEWLVGMQSRGGGWGAFDVD
NSAMWLYRIPFCDFGKVTDEPSADVTAHSLELLGTLGVERDAAERGVEWLLSEQEEDGSW
FGRWGVNHLYGTGAALPGLEACGIPHDHPSMRRAVAWLDSVQQESGGFGEDIRSYGNPAW
RGRANFTTASQTAWALLAYVAAGNAEDLATRRAADYLCAAQRTDGDWEEEHFTGTGFPLD
FMIRYHLYRITFPLLALGRLRERLAG
>A0A7V9CSB7|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MIVATQTRSALDAAIGAASERLLELQHPDGWWKGELESNATMVAQHLFWHHFLGLRDPES
DRRLANELLARRQADGTWSIWWEGQPDLSTSVEAYAALKLVGVDPGPAACDFIRAAGGIA
ATRIFTRSFLALLGQWPWQRIPTPPVELILLGPGAPFSVYDFACWARQTIVPLSAVMALR
PVRETPIDLSEIGARPGETRRPRPPGRLRRRALAAAERWVRERQEADGSWGGIQPPWVWS
MIMLAALGRGPDDEALARAVSGWDGFMVDDGERLRPEACQSPVWDTGLAVLALRAAGVEP
EHPQLVRAGRWLLEEEVMVKGDWSIRRPGLAPGGWAFEFQNDLYPDVDDTAVVSLALREL
GLGEGAIRRGLDWTAGMQCGAGGFAAFDCENTNAWLYRLPFCDFGAVIDPPSEDVTAHAL
EALLLEPGYAKTTRLAVDYLLRAQQPDGSWWGRWGVNHLYGTAAVLPALEAYGLPYGHPA
FRRAVAWLDSVQNADGGFGEDIRSYHEPAARGRAVSTASQTAWALLAYVAAGEEDRGSTG
RAADYLCATQDAQGDWREAHYTGTGFPTDFMIRYHLYRLYFPLLALGRLRERLHG
>A0A3D8GRW7|squalene-hopene cyclase|EC 5.4.99.17|Neobacillus piezotolerans|TrEMBL
MRHRVYKEMNRIANQIVLDQSEDGAWRYPFETGIASDCSMIILLRTLEISDEDFIKELVK
RIAGKQQKDGSWKLFHDEEKGNLTATVEAYYALLYSGYRDRKDKEIQAARRFIMANGGAT
EVHMFLKLMLAMTGQCQWPHFPINIEVMLLPDSFPINLFDLSVYGRANIIPFLILANTNF
RKRTKRSPNLSDLFQRKDVRFFTEEQSEEARSVIKWIKQGIQGLKYHGNLRELTLYRAEK
YMLDRIEPDGTYLNYFSTTFLMIFALLARGYPTTHPVITRAVQGLKAMACRIDGELHCQY
TTATVWNTTLLSYAMQESGVPYSSKTIQKANQYILSRQHLKYGDWVIHEPDLLPGGWGFA
DLNTIHPDIDDTTAALRAIRTLATEQAEYRQAWDRGVNWLISMQNKDGGWAAFEKNVDKK
ILNLLPIEGGKDLLIDPSTVDLTGRTLEFFGNYTHLDLHHPMVKDGIRWLLRHQNSDGSW
VGRWGVYIYGTWAAVTGLIAVGVSPNHPAIQKALAWLRSIQNPDGGWGESCKSDIKNCYV
PLGESTRTHTAWALDTLISAATGVTPEIENGAAFLVDKKEKDWTATYPKGRGMAGSFYLN
YHCYEYVFPLLSLAHYQKLADGQLLTEKPHKDFK
>A0A7Y8QXL2|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium elkanii|TrEMBL
MLARDHSVAVDPVALEKSISKATEALLGYRQSDGHWVFELEADSTIPAEYILLRHYLAEP
IDAGLEAKIGNYLRRVQGAHGGWPLVHDGPFDMSASVKSYFALKMIGDSVDAPHMVRARE
AIRSRGGASGSNVFTRFLLALYGVVTWRATPVLPIEIMLLPMWSPFHINKISYWARTTMV
PLMVLAALKPRAKNPKDVGIDELFLEDPKSVRMAPKAPHQSPSWFYLFRSLDAVLRVIEP
MFPKRLRQRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYEALGKDESFPPRAITRRG
IDKLLVISEHEAYCQPCVSPVWDTALASHALQEAGGDDTLAKAKQGLDWLKPRQVLELKG
DWAVKAPDVRPGGWAFQYNNDHYPDLDDTAVVVMAMDRVRRHTGTREYDEAIARGREWIE
GLQSRDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLGQLGETAESNRA
MADGVAYLRRTQLAEGSWYGRWGLNYIYGTWSVLSALNVAGVDRNDPMIRKAVDWLASVQ
NQDGGWGEDAVSYRLDYKGYEVAPSTSSQTAWALLGLMAAGEVENPAVARGVEYLKATQT
EKGLWDEQRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNSRVVGVGM
>A0A7W8F8U5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces albaduncus|TrEMBL
MTATTDGSTGAAWPSRVPAASETDTHTDSDIPVATGVPDVAARAMRRATDFLLSRQDDQG
WWKGDLETNVTMDAEDLLLRQFLGIGDEDTTRAAALFIRGEQRQDGTWATFHGGPGELST
TIEAYVALRLAGDPPDAPHMARASAWIREQGGIAASRVFTRIWLALFGWWKWEDLPELPP
ELIWFPSWLPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPHRPNPPRPLA
PAASWDGAFQRLDKGLHTLRKAVPRRLRRAAVNAAARWIIERQENDGCWGGIQPPAVYSI
IALHLLGYDLNHPVMRAGLESLDRFAVWREDGARMVEACQSPVWDTCLATIALADAGLPA
DHPQLVKAADWMLGEQIVRPGDWSVRRPHLPPGGWAFEFHNDNYPDIDDTAEVVLALRRV
KHHDPERLDNAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADV
TAHVVEMLAVEGLAHDPRTRRGLQWLLAEQEPNGAWFGRWGVNYIYGTGSVVPALAAAGI
PGSHPAIRRAVAWLESVQNDDGGWGEDLRSYRYAREWSGRGASTASQTAWALMALLAAGE
RESRAVERGIEWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGE
PFAKRPVVAKADPDEAEATKEQSLAEAKGS
>A0A3N9IMX9|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cenocepacia|TrEMBL
MIRRMNKMAPSPWSALDTAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDVRQEKMARYLRANQRLDTHGAWDLYVDGAPDVSCSVKAYFALKAAGDSEQAPHMTRA
RDAILKLGGAARSNVFTRILLATFGQVPWRAAPFMPVEFVLFPKWAPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNVSIRELFVTPPEEERQYFPPARGMRRLFLALDRMVRPVEPL
LPKRLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMQVLGYPDDHPLRRDCENAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVAALETDETAGTLRELDARIARAY
DWLAERQVNDLRGDWLENVPADVEPGGWAFQYANPYYPDIDDTALVTAMLDRRGRTHRDA
DGTNPYASRVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRADDRASLARAIGYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALAGED
KSQPYIARALDWLRARQHADGGWGETNDSYLDPKLAGTNGGESTSNCTAWALLAQMAFGD
CESDSVKRGIAYLQSVQQEDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GAKDAGATTSSASGAPAARATDSALA
>A0A6G3BEH4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5594|TrEMBL
MTATTDGSTGAANLSAAPAGHPADTTTAADDVTAAARQAAERSVAHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPSDLSATIEAY
VALRLAGDRPDEPHMARASAWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPTEPNPPRKLAPAASW
DGLFQRLDKGLHLYHKVAPRLLRRIAMNVAARWIVERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMVEACQSPVWDTCLATIALVDGGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARLEAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLGAHPRTRRGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALVAAGLPAAHP
SIRRAVTWLESVQNDDGGWGEDLRSYTEEKWIGHGESTASQTAWALLALLAAGRRDSRAV
ARGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRT
GAAQGA
>A0A6H1P765|squalene-hopene cyclase|EC 5.4.99.17|Priestia megaterium|TrEMBL
MSNTKKGIDWIIKKLRKDQSPDGSWNYPFETGQSTDAYMIILLRTLELNDEELIQGLVSR
ILSKQGENGAWKLYYDEDEGNLSSTVEAYYALLYSGYVKKDDKRLRAAKRFIVSKGGLEE
VSIFTKVMLSLTGQYIWPDFSPLPVESLLLPHYFPINFYSFSVFGRANLTPIILLADKKF
FIKTKKSPNLSELHLHRNQDKPWFRSAEYRSLLSFIEEGVKRLMGLPEQLHQLAIERAKK
YMLDHLEPDGTFYSYYSSTFLMIFALLSLGYKKTDPVISKAVKGLIAMKCDINGSPHMQY
TTANVWNTSLIGYALQSAGVLADDPMVMKANRYLLDHQQHKFGDWVIHNPKTMPGGWGFS
DVNTMNPDVDDTTASLRSISRIVPHERHAWDRGLSWLLSMQNDDGGWAAFEKNINTKLFE
FLPIEKGEFLLTDPSCADITGRTLEFLGNYTNLSRDHKAINKGVNWLLKNQLKDGSWYGR
WGICYLYGTWGAVTGLLAAGVPTSHTAIQKAVNWIQGIQNEDGGWGESCHSDSEKAYVPL
RASTLTHTAWALDTLLTTSEKPTTQIRKGISYLIASLEKQDWTTNYPKGQGMAGGFYIHY
HSYRYIFPLMAMSHYHKKFES
>A0A5N9E0Q1|squalene-hopene cyclase|EC 5.4.99.17|SAR202 cluster bacterium|TrEMBL
MVRRARLCGRKEPKSGDATTVAQLKHSDVNQAADEAVQRSQDYFRRTQYPEGYWWGELES
NPTMEAEYLMLCHFTGRHDQERWRKICNYILSKQRSDGSWSQYYEAPGDVSTSVECYFAL
KLAGHSPDTEPLRKAREFILSKGGIPKVRVFTKIWLALFGQWDWKGTPNMPPEMIFLPSW
APFNIYEFASWARATVVPMLIILTRQPYCAVPESADIGELYPGGREGTDYHLPKPTGGFG
WSKALYWADKLVGLYQRLPVHPFRGRAERKIIQWVLDHQEADGSWAGIQPPWVYSLITLH
TLGYGSDHEAVKKGFQGFERFALEDEDKCNVQACISPVWDTCIAQLALLESGIDPEDPMV
QSSARWLMDKQIYATADWQVRAKGTRPGGWSFEFDNLIYPDVDDASIVVMALDQVRLPEA
EEPRRADSIQRGVEWMAGMQSKNGGWAAFDKDNNKKYLTKIPFSDFGETLDPPSVDVTAH
LLEMYGRLGYNKENRAVDRGFAYVISEQEEDGSWFGRWGVNYVYGIGAVLPALEAIGEDM
SQAYIRLAVDWTVAHQNQDGGWGESCGSYVDPNLHGVGPSTASQTAWALLGLVAAGEHES
EAAQRGLVYLAETQLEDGTWDEPYFTGTGFPGYGVGERLKAMPDIGETSYQGLDMPAGFM
INYHLYRNYWPLLALGRYSQAVSGRL
>A0A150LMW1|squalene-hopene cyclase|EC 5.4.99.17|Parageobacillus caldoxylosilyticus|TrEMBL
MTVKREQAPDGSWRYPFETGISTDAYMIILLRTLEINDEDLIRKLVERIESRQEGNGAWK
LFYDEGEGNVTATVEAYYALLYSGYRKKTDPHMQAAKQRILEMGGIEKVHMFAKFMLAMT
GQYRWPRFFPIPVEFLLLPPSFPLHFFDISVYGRANLTPLLILTDNKYYRKTRKSPDLSD
LFLSQADHGEKWGLRADRLFLSYLKQSLIGLPGQIHAVAKQRAVQYMLQRLEADGTFYSY
FSSTFLMIFALLSLGYPKDHPIIVKAVNGLKTFRCSINGYTHMQYTTATVWNTALASYAL
QEAGVPPSDAAIEKANRYLLSRQHYRYGDWAVHNPYSLPGGWGFSNINTINPDVDDTTAS
LRAIYRQASKKTLFRHAWDRGLHWLFSMQNDDGGYGAFEKNVNKRLFHYFPIQGAEFLLT
DPSTADLTGRTLEFLGTFANLTKDHPAIARGVEWLIDHQEKNGSWYGRWGICYIYGTWAA
VTGMIAAGVPPTNHAIQKAAKWLLSIQNSDGGWGESCKSDSAKTYVPLRASTATHTAWAL
DALIAVFDQPIPAIQAGIQFLLQSIKKEDWTASYPTGQGMAGGFYIRYHSYRRVFPLLTL
SHYEKKFGSLPT
>A0A7H8JZZ6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. NA04227|TrEMBL
MTATTDGSTGAPVPLTAASATGTAPDDIGGRANEAARRATEYLLSLQDPEGWWKGDLETN
VTMDAEDLMLRQFLGIRDEKTTRAAAQFIRGEQRADGAWATFYGGPGELSATIEAYVALR
LAGDAPEAPHMAKASAWIRERGGIAASRVFTRVWLALFGWWKYEDLPELPPELIYFPHWL
PLNIYDFGCWARQTVVPLTVVSALRPVRPAPFALDELHVDPAVPRPAKPLAPMGSWEGAF
QRLDKAVRAYRKVAPRRLRRAAMRAAAQWIVERQENDGCWGGIQPPAVYSLIALHLLGYD
LDHPVMRAGLKALDEFAVWREDGARMIEACQSPVWDTCLATIALFDAGLPADHPQLVKAA
DWMLGEQVLRPGDWSLRRPELPPGGWAFEFHNDNYPDIDDTAEVVLALRRVAHPDPERVE
GAVARGVRWTLGMQSRNGAWGAFDVDNTSRMPNRLPFCDFGEVIDPPSADVTAHVVEMLA
HEGKADDPRARRGVQWLLAEQEPSGAWFGRWGVNYVYGTGSVVPALVAAGLAPGHPAVRR
AVRWLEAVQNEDGGWGEDLRTYLPGGGQGVGESTASQTAWALLALLAAGERESAAARRGV
GFLVDTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGELFTGAGR
>B6JG70|squalene-hopene cyclase|EC 5.4.99.17|Afipia carboxidovorans (strain ATCC 49405 / DSM 1227 / KCTC 32145 / OM5)|TrEMBL
MTSDTASAAALDPRRLATSITRASRALHDVQQPDSHWVFELEADVTIPAEYVMMRHYFAE
PVDAEIEAKIAKYLRRMQNDNGGWSLFYGHEFDMSASVKAYYALKMIGDSPDAPHMKKAR
EAMLARGGASRANVFTRIMLALFGQVSWKAVPMMPVEIMLLPRWFPFHLTKVSYWARTVI
VPLLVLMTLKPRAKNPRGIGVRELFLEDPQTVGPTPKAAHQSQLWFTSFDIIDRVLRITD
PFFPKGMRKRAIAKAEAFVTERLNGVDGLGAIFPAMVNSIMMYDVLGYPPNDPNRALARE
SVERLLVIKDDEAYCQPCVSPVWDTALAAHSMLESGEAADIEAAKAGLDWLLPRQVLDLK
GDWADKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRVRRLDGTTKYDEAIARATEWI
LGLQSENGGWAAFDADNLEYYLNNIPFADHGALLDPPTEDVTARCLSMLAQLGDTLETSE
PMRRGVEYLRKTQLPDGSWFGRWGINYVYGTWSVLCALNAVGVPHDDPMIAKAADWLESI
QNEDGGWGEDGNSYKLNYKGYERAATTASQTAWATLALMAAGRVDRDATQRGIDNLVQSQ
EADGFWGEPYYTGGGFPRVFYLRYHGYSKFFPLWAMARYRNLRSSNSRFVGAGM
>C7Q017|squalene-hopene cyclase|EC 5.4.99.17|Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)|TrEMBL
MTDVIDKAVAATGPADPSQGAAATLQAAADHLLGLQDDAGWWKGELETNVTMDAEDLLLR
QFLGIRTEEVTREAGDWIRSQQRADGTWANFFDGPADLSTTIEAYTALRMAGDAKDAEHM
RAARTYILDSGGIEASRVFTRIWLALFGEWQWSDLPVMPPELIYLPKWFPLNVYDWACWA
RQTVVPLTIVNALRPVRPLGFDLKELRTGRRAPAQRGLFSTLDRALHVYERKPLRSVRDA
ALRRSADWIIARQEADGSWGGIQPPWVYSLMALNLLGYGVDHPVMRKGIEGLDRFTIRDE
RGRRLEACQSPVWDTVLAMTALRDAELPENHPALVKAADWVLGEEITNPGDWSVRRPRVA
PGGWAFEFDNDGYPDVDDTAEVVLALNRVAHPDAPAAIRRGVDWLEGMACKDGGYGAFDA
DNTRTLALKLPFCDFGAVIDPPTADVTAHTLEAYAALGLANSRASQRALEWLVKAQERDG
SWFGRWGANHVYGTGAVVPAMVAVGVDPEDEMIRRAVRWLEEHQNDDGGWGEDLRSYRDK
SWIGRGVSTASQTAWALLALLAAGEERGTAVEQGVRFLIRTQRADGTWDEDHYTGTGFPG
DFYLNYHLYRLVFPISALGRYVRAVGAAGDGGDAGHAGHAGTVS
>A0A534HF44|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MSRKVGTSAALAGTEGLLRADAPARKLPGEKLSPLEYAIAAARDELIRLQRPDGSWELEL
EADCTIPAEYIMMMHFLGELDSALEAKLAEYLRQRQAGYGGWPLYHGGAFDMSCSVKVYF
ALKLAGDDPESPHMARARTAILERGGAAACNVFTRIALALFGQLPWRGVPYIPVEIVLLP
RWFPFNIHRVSYWSRTVMVPLLILCTLKPRARNPRNVDIRELFTTPPGQERRYFRRPLGG
SAALARAFYFLDRFARRLDGLIPRALREHALERAEAWMLERLNGEDGLGAIFPAMVNALE
ALAVRGYSPDHPHRRGAKRALEKLLVEDYSSAYCRPCVSTVWDTALASLAMQEEGSAGAR
AAALRGLEWLEPRQLLDEPGDWRTRRPHLPGGGWAFQRANSYYPDLDDTAAVAWSMHRST
DPGRFSFALSRALDWLVGMQSENGGFASFDVDNTSYYLNEIPFADHGALLDPPTSDVTAR
VVTALARVGRPEDRGALTRAIDYLRREQEANGSWFGRWGTNYVYGTWSVLCAFAAAGIGR
DDPAVERAVRWLESRQNPDGGWGESNDSYEPGRAGTSAPSTPHQSAWAVLALIAAREAGS
DAVRRGIEYLLRTQRPDGLWSDPSFTAPGFPRVFYLRYHGYCAYFPLWALAAYRNSTAAG
PGTVH
>A0A534AR14|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
IALALFGQLPWRGVPYIPVEIVLLPRWFPFNIHRVSYWSRAVMVPLLILCTLKPRARNPR
NVDIRELFTTPPEEERRYFRRPLGGSAALARVFFCLDRLARSLDGLIPRALREHALERAE
AWMLERLNGEEGLGAIFPAMVNALEALSVRGYSPDHPHRRGAKRALEKLLVEDYSSAYCR
PCVSTVWDTALAGLAMQEEGSAGARAAALRGLEWLEPRQLLDDPGDWRTRRPHLPGGGWA
FQRANSYYPDLDDTAAVAWSMHRSTDPGRFSFALSRALDWLVGMQSENGGFASFDVDNTS
YYLNEIPFADHGALLDPPTSDVTARVVTALARVGRPEDRVALTRAIDYLRREQETNGSWF
GRWGTNYVYGTWSVLCAFAEARIGPDDPAVERAVSWLESRQNPDGGWGESNDSYEPGRAG
ASAPSTPHQSAWAVLALI
>A0A6G2W9I4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8369|TrEMBL
MTATTDGSTGAANPARATAHGPTDTTTSADDVTAAARRAAERSIEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDADTTRAAALFIRGEQLGDGTWNTFYGGPSDLSATIEAY
VALRLAGDRPDEPHMARAAGWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFL
PTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPDHPSPPRKLAPPTSW
DGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVMKAGLDSLDRFAVRREDGARMVEACQSPVWDTCLATIALADAGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARVEAAIARGVRWNLGMQSRNGAWGAFDADNTSGFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLARHPRTREGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALIAAGLPAGHP
AVRRAVSWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDTPSV
ARGVRWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRFVHGDPFADRA
DAVEGA
>A0A5S4GTU5|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura geliboluensis|TrEMBL
MTTLETPETPEAAGTRTAAEALDAARDHLLLLQSPEGWWKGELQTNVTMDAEDLLLREFL
GVRTDEDTVEAARWIRSQQAPDGTWANFHDGPPDLSTTVEAYVALRLAGDPPDAGHMIRA
AAYVRGEGGVPATRVFTRFWLAMFGHWSWDELPVVPPEMLFLPRWFPLNVYDFACWARQT
IVPLTVVGALRPVRPLPFGLDELVPDYDVPEPRRRRLPGWGEAFGALDKALHVYQRHAHR
RRPLKGVREAALRRAAEWIIARQERDGSWGGIQPPWVYSLIALHLLGYGLDHPVVRRGLD
GLERFTIRDERGRRLEACQSPVWDTVLAMNALADAGLPAGHPALERAAEWVLGEEVRGPG
DWSVRRPGLPPGGWAFEFDNDVYPDVDDTAEAVIALNRVRHPAAEPAIERGVRWMAGMVS
RDGGFGAFDADNTRTLCRRLPFCDFGEVIDPPSADVTAHVVEALAHRGMADSLLAKRAVV
WLLKAQEPDGSWFGRWGANHVYGTGAVVPALIAAGVRPEKPAIRDAVGWLERHQRDDGGW
GEDLRSYRDRSWVGHGASTPSQTAWALLALLAAGERGPAVEGGVRWLAEHQRPDGTWDED
HFTGTGFPGDFYINYHLYRLVFPLSALGRYLGAGAAAPGGPGGGSKEAF
>A0A431NDL7|squalene-hopene cyclase|EC 5.4.99.17|Pseudonocardiaceae bacterium|TrEMBL
MTLTAPELLATRTPRAALDAAVAFLRAGRHPDGWWQGELETNVTMDAEDLLLREFLGIRT
DTETAEAARWIRSRQRADGSWATFQDGPADLSTTIEAWVALRLAGDAPDAEHMLRAQKFV
VSQGGLERSRVFTRIWLALFGLWSWDELPDMPPELIFLPKWFPLNVYDWSCWARQTVVPL
TVVATLRPARPLPFGVDELRTGAAAPPLAKPWTWAGAFQRLDKVLHAYSRRPLRGVRRLA
MRRAAEWVLARQEADGSWGGIQPPWVYSILALHLLGYPLDHPAVAAGLRGLDRFLIREET
PDGVVRRLEACQSPVWDTCLAVTALLDAGVPADDPDVLAAAEWMLAEEVTGVRGDWAVRR
PDIPTGGWAFEFDNDGYPDTDDTAEVVLALRRVAHPVPERVRAAVDRGVAWTVGMQSRDG
GWGAFDADNTRELVTKLPFCDFGAVIDPPSADVTAHVVEMMAAEGLAHTTECRRGVDWLL
AAQERDGSWFGRWGANHVYGTGGVVPALVAGGIDPDTPPIRRAVAWLERHQNTDGGWGED
LRSYSDPSWIGKGASTASQTAWALLALLAAGERDSAATTRGVQYLVDTQLPDGSWEETLY
TGTGFPGAFYIRYHLYRMVFPISALGRYVNGHTS
>A0A7W1BA39|squalene-hopene cyclase|EC 5.4.99.17|Chthoniobacterales bacterium|TrEMBL
MAKEAPPRLATSVELADAIGLAQQNLLRQQKPDGHWVGELMVDSTLCSDYVLFMHWLGEV
DEVLQRRCAKHIRKRQLPDGGWNIFYGGPSEINACVKAYFALKLAGHSPDAPFMQEARAN
ILRLGGIPRMNTYSKLYLALLGQFPWKYLPAIPVEMLLLPSWCFFNIYKMSSWSRAMLIP
LAIINHFKPTRDLPEDKQLHELYPVGTEDNDFTLRRDQRLLTWRNFFLRADRALKILGRW
HSRPLRQRALEEAERWMVERIGEGSDGLAAVFPAMLNSIIALRALDYPKDHPLYKKALYD
FSGLFVDDPEDFRIQPCLSPVWDTAINIIALAESGFPAQHPSLQRAAQWLLDREVRARCD
WTINNPHPEASGWAFEYNNVFYPDTDDTAMVLMALRLVRPNEQGELAEIFERALEWQLSF
QCCDGGWAAFDKDVTRHWLEDMPFADHNAILDPTCSDLTARTLELLGYIGFNPGRPLVRR
AVRYLRETQEDDGSWYGRWGVNYIYGTWQVLRGLCAIGEDMTENWILRGRDWLESCQNDD
GGWGESCASYESPDLKGKGASTASQTAWALMGLCACGDLDRPSVQRGLRYLLDTQRDDGA
WDELEITGTGFPRVFYLKYDMYRQNFPLLALATYVNYRSGIGHYQSFYRWIGT
>Q5NM88|squalene-hopene cyclase|EC 5.4.99.17|Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)|TrEMBL
MGIDRMNSLSRLLMKKIFGAEKTSYKPASDTIIGTDTLKRPNRRPEPTAKVDKTIFKTMG
NSLNNTLVSACDWLIGQQKPDGHWVGAVESNASMEAEWCLALWFLGLEDHPLRPRLGNAL
LEMQREDGSWGVYFGAGNGDINATVEAYAALRSLGYSADNPVLKKAAAWIAEKGGLKNIR
VFTRYWLALIGEWPWEKTPNLPPEIIWFPDNFVFSIYNFAQWARATMVPIAILSARRPSR
PLRPQDRLDELFPEGRARFDYELPKKEGIDLWSQFFRTTDRGLHWVQSNLLKRNSLREAA
IRHVLEWIIRHQDADGGWGGIQPPWVYGLMALHGEGYQLYHPVMAKALSALDDPGWRHDR
GESSWIQATNSPVWDTMLALMALKDAKAEDRFTPEMDKAADWLLARQVKVKGDWSIKLPD
VEPGGWAFEYANDRYPDTDDTAVALIALSSYRDKEEWQKKGVEDAITRGVNWLIAMQSEC
GGWGAFDKDNNRSILSKIPFCDFGESIDPPSVDVTAHVLEAFGTLGLSRDMPVIQKAIDY
VRSEQEAEGAWFGRWGVNYIYGTGAVLPALAAIGEDMTQPYITKACDWLVAHQQEDGGWG
ESCSSYMEIDSIGKGPTTPSQTAWALMGLIAANRPEDYEAIAKGCHYLIDRQEQDGSWKE
EEFTGTGFPGYGVGQTIKLDDPALSKRLLQGAELSRAFMLRYDFYRQFFPIMALSRAERL
IDLNN
>A0A3N8PXB1|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia contaminans|TrEMBL
MIRRMTTATPSPWSALDTAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDIRQEKMARYLRATQRLDTHGGWALYVDGDPDVSCSVKAYFALKAAGDSEHAPHMVRA
RAAILKLGGAARANVFTRILLATFGQVPWRATPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNVSIRELFVTPPDEERRYFPPARGMRRLFLALDRTVRHVEPL
MPKGLRQRAIGHAEAWCAERMNGEDGLGGIFPPIVYANQMMQVLGYPDDHPLRRDCDNAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVAVAEDGEPGDARRALDERIARAY
DWLAERQVNDLRGDWIENAPADVQPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRTHADA
DGTNPYAPRVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRADERESVARCIDYVKRTQQPDGSWWGRWGTNYIYGTWSVLAGLALAGED
KSQPYIARAIEWLRSRQHADGGWGETNDSYIDPKLGGTNGGESTSNFTAWALLAQMAFGD
CESDSVKRGIAYLQSVQQEDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GATAARAAAAHGATAVKSAATVVA
>A0A6G3WBI9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID9944|TrEMBL
MTATTDGSTGATLPTRAAAASEPVLTTPVAAGVHQAAEHAVRRATDFLLSRQDAEGWWKG
DLETNVTMDAEDLLLRQFLGIQDEATTHAAALFIRGEQREDGTWATFYGGPGELSTTIEA
YVALRLAGDAPDAPHMAKAAAWVRARGGIAASRVFTRIWLALFGWWKWEDLPELPPELIY
FPTWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAQPNPVKPLAPAAS
WDGAFQRLDKALHAFRKVAPKRLRRSAMNTAARWIIERQENDGCWGGIQPPAVYSIIALH
LLGYDLQHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQ
LVKAADWMLGEEIVRPGDWSVRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHD
PERVDRAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGLAHDPRTRRGIQWLLEEQEPDGSWFGRWGVNYIYGTGSVVPALTAAGLPGSH
PAIRRAVAWLKRVQNDDGGWGEDLRSYRDSKKWSGKGASTASQTAWALMALLAAGERDSE
AVERGVRWLADTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFAA
QAPAGRPLAEAKGS
>A0A7X2Z8G0|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus validus|TrEMBL
MSETNSEIQRLTEELLRLQKEDGSWRFCFENGTVTDAYMIVVLRTLQEPDESLIRQLHDR
IAAAQQADGSWKLFHDEEEGNLSATVEAYYALLYSGYSATSDESMRKAKQYILSKGGIRS
IDSLLTIVLLAATGQYPWPASLFIPLEFLLLPPSFPLNFFDFSAYARVHLAPILLMADRR
FAMKTQASPDLSDLSDLSAARSGSLDPSGPAGQRQPADGFQALLDEIKAGLGKLVGIPGK
LHMAAAKRAEQYMLERIEPDGTLYSYASCTFLMIFALLALGYDKQHPVITRAVRGLTAMV
CSSDGKMFLQNSPSAVWDTALLSHALQEAGVAPESKAIRSAASYIVSKQQRTLGDWSLHN
RNPVPGGWGFSDSNTINPDVDDTTAALRAIKRLAQSDPPSRDAWNRGLNWLLSMQNRDGG
WPAFERDTDNKLLAWLPIDGAQATAIDPSSADLTGRTLEFLGNTAGLGLKHPFVRRGTDW
LIDHQEEDGSWYGRWGICYIYGTWAAMTGMISAGVDTGHPAVQRGVSWLSSIQNPDGGWG
ESCRSDRLMRYVPLGASTPSQTAWALDALIAFHPKPVPEVEKGMQRLLALLIEDGWASAY
PTGAGLPGAFYMHYHSYRYIWPLLALSHYRKKYSG
>A0A3N8CWX3|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp9012|TrEMBL
MNDLTDMANLSAGTVPAGLDAAVASATDALLAAQNADGHWVYELEADSTIPAEYILLVHY
LGETPNLELEQKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPIAKNPRGVRIDELFIDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKSIEKLLVVHEDEAYCQPCLSPVWDTSLVAHALLETGDARAEEAVLRGLDWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLKQTDTYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTSDVSGRCLSMLSQLGESAL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRVKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLI
AQQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A4R5EM58|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. 6K520|TrEMBL
MTTTEAPGLTGAAAAAVEAARDHLLGLQSPDGWWKAELETNVTMDAEDLLLRQFLGIRTD
GETREAARWIRSRQRDDGTWANFFGGPPDLSTTIEAYVALRLAGDPADTAHMRRAARHVR
EAGGIEASRVFTRIWLALFGQWPWDDLPVMPPELMFLPSRVPLNVYDWACWARQTIVPLT
VLGSLRPVRPLPFDLAELRCGVRPAQDAKGWGRVFATLDRALHVYERRPVRPLRTAALRR
AAEWIIARQEADGCWGGIQPPWVYSLMALHELGYGLDHPVIRRGLAGLDRFTIRDEKGRR
LEACQSPVWDTVLAMNALSDAGTPPGDPALLRAARWIAAEEVRGPGDWQVRRPSLPPGGW
AFEFDNDVYPDTDDTAEAILALRRSGLPDAAEPIGRAVRWLTGMASRDGGFAAFDADNTR
ELCTKLPFCDFGAVIDPPSADVTAHVVEALAKEGHARTTVVKRAVVWLLKAQEADGSWFG
RWGANHVYGTGSVVPALIAAGVRPDRPAIRRAVAWLEEHQNDDGGWGEDLRSYDDPAWIG
RGASTASQTAWALLALLAAGERSSAVDGGVRWLVDHQRPDGNWDEEHFTGTGFPRDFYIN
YHLYRLVFPISALGRYVAAPASTDLKEAGES
>A0A7C3BKY5|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
MAQSRHQTAGATLATADPAGLAQAIRRAQDYLLSIQSQEGYWVGELEADVTVTAGYIPLM
YFMTGEVDPARQQKVVNYVKSKQRPDGSWSTYYDGPGDLSVTIQAYFALKLAGISPEEPF
MRRAREFVRRRGGIAKANTLTKMWLALFGQYDWRGTPTIPPEIILLPSWFYFNIYEFASW
SRATIVALMIVSAKRPVCPVPQWARVDELYLEPEDKRDYSLSKAERFLSWENFFLWLDRF
FKIWEKSPFQPGRGLALRRTERWLTEHQEADGSWGGIMLPWVYSLIAFKSLGYPLDHPVI
ARGLKGLEDFILEDDATMRLQPATSPIWDTAWAVIALRDSGLPAGHPALVKAARWLLKQE
VRVGGDWQVKSPETEPGCWAFEFENDFYPDIDDTAVVPRALLRVKLPGKEEADKVQAVAR
GRRWVVAMQSDNGGWAAFDRNNHRRILAHIPFADFMTPLDPTSPDVTAHAIELLAELNGD
DSSLRRALAYLKREQEPDGAWYGRWGVNYIYGTGLVLAGLQAAGEAMAQDYIRRAVSWLL
RHQNEDGGWGETCHTYEDPNYRGAGPSTASQTAWALLGLLAAGEKTNPAVKRGISYLLKN
QKEDGSWPEDAYTGTGFPRAFYLRYELYRIYFPLLALAKYRASLEGVDYEPR
>A0A3N8CB18|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp9125|TrEMBL
MNDLTDMPTLSAAMVPAELETAVQRATDALLAAQQPDGHWVYELEADSTIPAEYILLVHY
LGETPNLELEQKIGRYLRRIQQPGGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARKAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPIAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANSVMMYAALGYAEDHPNRAI
ARESVEKLLVVKEDEAYCQPCLSPVWDTSLAAHALLETEDPRAEEAVVRGLEWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANPHYPDVDDTAVVVMAMDRVEKLKHSDAYRESISRAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETAA
NSEAARRSLDYMLKEQEPDGSWYGRWGMNFVYGTWTALCSLNAAGLGPEDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLDYRGYEQAPSTASQTAWALLGLMAAGEVNNPAVARGIDYLV
AEQQEHGLWDEARFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNATRVTVGM
>A0A3L7JUM9|squalene-hopene cyclase|EC 5.4.99.17|Falsibacillus albus|TrEMBL
MRDGVKMEMNRIANQFVLDQAENGAWQYPFETGIASDCSMIILLRTLEINDEEELIKELV
ERIAGKQEEDGSWKLFHDQEKGNVTSTVEAYYALLYSGYRDPKDEKIQAARRFILANGGA
SEVHLFLKILLALTGQCAWPHFPINIEVMLLPDSFPINLFDLSVYGRANLIPFLLLANLN
FRRRTPRSPDLSDLFQQRDVRFFTEDQEEDVRSVIQFIKQGVKSLKYHGNLRELTLYRAE
KYMLDRIEPDGTYLNYFSSTILMIFALLARGYSNTHPVITRAVKGLKAMTCRIDGKLHCQ
YTTATVWNTTLIAYALQEAGVPYSSGTIQKANQYILSRQHLKYGDWAIHEPNLLPGGWGF
ADMNTIHPDIDDTTAALRAIRTLAIEQVVYRQAWDRGVNWLLSMQNRDGGWPAFEKNVDK
KLLSLMPIEGGKDLLIDPSTVDLTGRTLEFFGNYTHLDQQHPKMKRGVRWLLKQQKADGS
WVGRWGVYIYGTWAAVTGLLAVGVSKEHPAIQKALTWLLKNQNSDGGWGESCKSDLENSY
VPLGESSRTHTAWALDTLITAATSVTPEIETGAAFLVEHKEKEWTTTYTKGRGMAGSFYI
HYHCYEYVFPLLALAHYQKLAGGQLLKDLAQENM
>A0A846E550|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO2B7|TrEMBL
MQTQDRIVESGVTEAIANSQSYLLAQQYPDGYWWAELESNVTITAEIVLLHKIWGTDKQR
PLHKAEAYLRSQQQKHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDSALVRARDFILR
RGGITKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPEWFPFTIYEMSSWARGSTVPLLI
VFDQKPVFDIQPRINLDELYTEGADHAKFELPRNSDWTDLFVLLDDGFKLAEDLNLVPFR
KEGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPIVQRGLEAIDRFAIE
TPDSYRVQACVSPVWDTAWVLRGMVESGLEPDHPALVRGGEWLLQQQILDYGDWVVKNPQ
GKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLKQAAMARGLAWIASMQCKQGGW
AAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEMLGSCNLSIESQQLEKAIAFLIQ
EQETDGSWFGRWGVNYIYGTSSALSALSKVAPHSHQRSIERGAAWLVKCQNLDGGWGETC
LSYDDPSLKGVGISTASQTAWALIGLMAAGEATGNWAMDAIEMGVNYLVSTQQPDGSWDE
TEFTGTGFPSHFYLKYHFYQQYFPLLALGRYQMSVLS
>A0A6G9GTM0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces liangshanensis|TrEMBL
MTATTDGSTGAVGPRAAAASEPTDTTTAAAGDLLVAARRATARSVEHLLGRQDAQGWWKG
DLETNVTMDAEDLLLRQFLGVLDPRTTEAAGLFIRGEQRADGTWATFYGGPGELSATIEA
YVALRLAGDSPDDPHMKRAATWVREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELIF
FPKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDADAPNPVKPLAPVAS
WDGMFQRLDKVLHAYHKVAPRRVRRIAMNAAARWIIERQENDGAWGGIQPPAVYSVIALH
LLGYDLDHPIMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLSPDHPA
LVKAADWMIAEEISRPGDWAVRRPELAPGGWAFEFHNDNYPDIDDTAEVILALRRVRHPV
PARLDAAVERGARWTLGMQSRNGAWAAFDADNTSPFPNRMPFCDFGEVIDPPSADVTAHV
VEMLAYEGMAQHPDTRRGIEWLLAEQEASGAWFGRWGVNYVYGTGSVVPALTAAGLPVTH
PAIRRAVRWLESVQNDDGGWGEDLRSYREEKWIGHGASTASQTAWALLALLAAGGRESRS
VERGVAWLAETQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPLASG
AISRKGS
>A0A7V7PQM7|squalene-hopene cyclase|EC 5.4.99.17|Aureimonas leprariae|TrEMBL
MTDDLVFESRDLDAPSLAEADAPSLPPTLNERIARATAGLLAHQKDDGHFCFELEADATI
PSEYVLLLHWLGEENRPLEAKIAAYLRRIQGVHGGWPLFTDGAFDMSASVKAYFALKMIG
EPLDAPHMVRARKAILSRGGAANANVFTRILLALYGQIPWRGVPVMPVEIMALPRWFPFH
LSKVSYWARTVLVPLLVLQALKPVAANPRGVGIAELFAVPPEKVKHWPKGPHQVAPWSQI
FGGIDRVLQVAEPRFPKASRQRSIEAAVAFVDKRLNGTAGLGAIYPAMANAVMMYEALGV
SRDDPRVRTAREAIDGLLVETGTEAYCQPCLSPVWDTALAAHALLEAGGEAEARAKAGLE
WLKPLQVLDHKGDWAEIKPDVRPGGWAFQYANPHYPDLDDTAVVAMAMDRADRNAGSQTY
AEAISRGAEWVGGMQSRDGGFAAFDADNTHHHLNYIPFADHGALLDPPTADVTARCISMF
AQLGETAETSPRLARAVEALIAEQREDGSWFGRWGMNYIYGTWSALSALNAAGHAPEAPA
VAKAADWLLAVQNPDGGWGEDGMSYRMDYRGFEPSPSTASQTAWALLGLMAAGRADDPAV
ERGVEYLSRTQDADGLWSDRLFNAVGFPRVFYLKYHGYAKFFPLWALARYRNLKAGNSRR
VTVGM
>C1F699|squalene-hopene cyclase|EC 5.4.99.17|Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / BCRC 80197 / JCM 7670 / NBRC 15755 / NCIMB 13165 / 161)|TrEMBL
MSVSERAQPGGNPIPGSTSQSAVKFGRIDAALEDVKRAIAGAKDRVFAQQSKDGWWCGEL
EADSMLEADYIFAHTLLGTGDAGKMKRALTEMLRYQNEDGSWSIYPGGPGNISLTVKCYF
SAKLMGMTADNPILVKAREWILAHGGVVECNTFTKIYLCFLGQYEYDAVPAIPPEIVLFP
NWFYFNIYEISSWSRAILVPLSIAYAKKPFKKIPPEQGIDELFVGGREKANLHLRWDSKN
LLSWRNFFLALDRVTHWFERVHIRPLRSIALKKAEKWMLARFEMSDGLGAIYPAMLNAII
ALRCLGYSLDDPQVLRAMDEFEKLGIDEPEGTAEYAEPTFRMQPCVSPVWDTAQAVFALG
EAGVPRNDPRMQKAADWLLSKEVRHKGDWAMKVRNAQPGGWYFEFNNEFYPDVDDSAQVL
LALNKVDNPRERYQYDVCQRAIDWIFAMQCRNGGWASFDKDNTKMIFQYVPFADHNAMLD
PPTVDITGRILEMLATYGYTRKDRRVEKAIKFIYDEQEPDGSWFGRWGVNYLYGTFLVLR
GLEAIGVWNHEPQIQQAAEWIRSVQNADGGWGETCGSYDDPNTRGVGPSTPSQTAWAILG
LLSAGDDRSDSVAKGIKWLLAHQKPDGGWDESTGSGSKHQALYTGTGFPRVFYLAYHQYR
DYFPLLALTNYEKAMERGE
>A0A7W9QAL2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces zagrosensis|TrEMBL
MTATAVESSTTLTAAQQATARAVDNLLALQDEAGWWKGDLETNVTMDAEDLLLRQFLGIS
DPETTAAAARHIRSQQRPDGTWPTFHGGPPEISATIEAYVGLRLAGDEPDAPHMAAASAW
VRGAGGIASSRVFTRIWLALFGWWSWDDLPELPPELIYLPKWVPLNIYDFGCWARQTIVP
LTIVSAKRPVRPASFALDELHIDPRRPNPARPLAPATTWDGAFQRLDRALHAYRKVTLRS
VRRSAIRSCARWIIERQENDGCWGGIQPPAVYSVIALHLLGYDLEHPVLRAGLASLERFA
VWRKDENGDPVRMVEACQSPVWDTCLATIALADAGLPADHPALVRAVDWMLDEQILKPGD
WSVRRPEVRPGGWAFEFHNENYPDIDDTAEVVLALRRVTHPDPKRVDWAIQRGAEWNLGM
QSRNGAWGAFDADNMSPFPNRLPFCDFGEVIDPPSADVTAHVVEMLVALGERNDPRTQRG
IDWLLSEQEPSGPWLGRWGTNYLYGTGSVVPALVLSGIPVSNPAIRRAVSWLESVQNEDG
GWGEDQRSYRDRQWAGRGVSTASQTAWALLALLAAGERESEAVRRGVTWLADTQCPDGSW
DEPYFTGTGFPWDFSINYHLYRMVFPITALGRYVRAEPFGVERQGV
>A0A385AU16|squalene-hopene cyclase|EC 5.4.99.17|Micromonospora sp. B006|TrEMBL
MTLTAGPATRPAPARDLVAALTGEPSGQTSPSIYESARLVALAPWLDGHDRRLAWLLGRQ
RPDGGWGGAGGYALVPTLSAVEALLTVLRRDGPAAAPAAAAHRGLAFLAGALRGGAPPDL
PATDLIVPALLTAVDRHLAGPAGPPPGLAEWAGRPRLPLPAGLDPDRLTRVRGLLAAGRA
VPEKLAHALEVAGELAYRASGVRPAASGAVGASPAATAAWLGRPEPGAALDYLRAVARPG
PVPCASPITVFERAWVLGILVRAGVPVGAPEPVLTELRAAVGPSGAATAPGLPADADTTA
VALYALARLGRAPGVGPLAGFDTGRHFCTWPGEDGASLTTNAHVLDALGEQPSGPGVTGA
RRRVTAWLLERQEPDGRWEDRWHASAYYATYAVLLALADHAPDGTARAAVERGVAWLLDT
QRPDGSWGRWHGTAEETAYGVLALAGAGRSGDARIAAALARGRRRLSELDGCDDEPALWH
DKDLYRPTQIVRAAVLAASGRAVEAGPP
>A0A6I4WDU1|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura rayongensis|TrEMBL
MTATAPVEPAGEPLETGAPRTAADALAAARDHLLGLQAKQGWWKGELQTNVTMDAEDLLL
REFLGIRSDYDTREAARWIRSQQAPDGTWANFHGGPPDLSTTAEAYVALRLAGDAPDAEH
MARAAAFVRAEGGLAATRVFTRFWLALFGAWEWDDLPVMPPEMIFLPAWFPLNVYDWGCW
ARQTIVPLTVVAALRPVRPLPFGLDELHAESAPRRRPRLGWDGAFHALDKALHLYEKRPR
KGLRRAALLRARDWIVARQEQDGCWGGIQPPWVYSLIALHLLGYGLDHPVMRRGIAGLER
FTIRDAQGRRLEACQSPVWDTVLAMNALADAGLPGDHPALLRAADWVLGEEVRGPGDWSV
RRPDLAPGGWAFEFDNDLYPDTDDTAEAILALNRVRHPGAEPAIERGVRWMAGMASKDGG
FAAFDADNTSRLVARLPFCDFGAVTDPPSADVTAHVVEALCARGMARTPVVRRAVVWLLK
HQEDDGSWFGRWGANHVYGTGSVVPALVAAGVRPDAPVIRRAVGWLERHQGADGGWGEDL
RSYRDAAWIGRGTSTASQTAWALLALLAAGERGPAVQRGIDWLVARQRPDGTWDEDEFTG
TGFPGDFYINYHLYRLVFPVSALGRYLAAQDAR
>A0A375CDH1|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus taiwanensis|TrEMBL
MSMNETAFANAAPQLDPAPRQPAAAHEPPAARAPAHALDHGIGRALDALLHQQRSDGHWV
YELEADATIPAEYVLMVHYLGEQPDLDLEARIARYLRRIQNPDGGWPLFHEGRSDISASV
KAYFALKMAGDDPQSAPMQRARQAIHALGGAEASNVFTRTLLALYGALPWTAVPMMPVEI
MLLPRWFPFHLSKVSYWARTVIVPLLVLNSLRPQARNPRGVGIQELFVGNCHTVRLPPRA
PHQHAGWYTVFRGLDALLRVAEPLFPRALRRRAIAAAQDFVRERLNGEDGLGAIFPAMAN
SVMMFDVLGVLPDDPARAVARRSVERLLVEHGDEAYCQPCLSPVWDTALAAHALLETGEA
RAVQAAGRALDWLKPLQVLDLRGDWAVRRPLVRPGGWAFQYANAYYPDVDDTAVVAAAMD
RFMRAHDAPGRYGEAVARATEWIVGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDPP
TADVSARCLSMLCQTGAPPGKSEPAARALRYLLAEQMPDGSWFGRWGTNYIYGTWSALCA
LNAAGLPPEAPELRRAVAWLARIQNADGGWGEDGSSYRLDYRGYEPAPSVASQTAWALLA
LMAAGAAQHPAVARGIDYLLRTQQPGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWALA
RYRNLQRGQGGQVSWGL
>A0A6B3GVR2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID7982|TrEMBL
MTATTNGPAGAAPSRPAPARPTTDTTTAPDSATVEAAAERARARAADHLLGLQSPEGWWK
GDLDTNVTMDAEDLLLRQFLGIRDEATTRAAALFIRGEQREDGTWATFHGGPPDLSTTVE
AYVALRLAGDSPDAPHMTRAAHFVRARGGIAEARVFTRIWLALFGWWPWDRLPELPPELI
FLPPWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPANPAPRTRLAPLA
SWNGAFQRLDRALHTYRKVAPRALRRAAMAAAGRWIIERQENDGCWGGIQPPAVYSMIAL
HLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALADAGVPADHP
QLVRAADWMLNEQIERPGDWSVRRPHLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHP
DTARLERAISLGVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDPPSADVTAH
VVEMLAAEGLGADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALIDAGLPAT
HPAIRRAVAWLESVQNDDGGWGEDLRSYRDQGRMARGASTASQTGWALMALLAAGERESA
AARRGVAFLADTQHEDGSWDEPYYTGTGFPWDFSINYHLYRQVFPLTALGRYTRGAAPEA
A
>A0A8J6WA86|squalene-hopene cyclase|EC 5.4.99.17|Nodosilinea sp. FACHB-13|TrEMBL
MQTQEPQQLTGIDSAIAAAQNYLLALQHPDGYWWAELESNVTITAEIVLLHKIWGTDSAR
PLAKAEHYLRSHQRDHGGWELFYGDSGDLSTSVEAYMALRVLGVPASDPALLKAKDFILK
RGGISKTRIFTKLHLALIGCYDWRGLPSLPAWVMLLESPSPFTIYELSSWARGSTVPLLV
VFDQKPVYKIEPAINLDELYAEGIANVRWELPKAGDWSDIFIWLDGAFKFAESINFTPFR
DEGLRKAEQWILERQEATGDWGGIIPAMLNSMLALRCLGYDVNDPVVRRGLRAIDNFAVE
TDDTYWVQACVSPVWDTALGMRSLTDSGLAPNHPSLVRAGEWLLEKQILDYGDWIVKNPQ
GKPGGWAFEFENRFYPDVDDTAVVAMALQDVTLPDEALKREAIARAVRWVATMQCKTGGW
AAFDINNDQDWINAVPYGDLKAMIDPSTADITARVLEMHGRLCREPGLAARYASDLSAQR
LERGLTFLLNEQEADGSWFGRWGVNYLYGTSGALSALALTAPERCQGAIARGANWLISCQ
NPDGGWGETCRSYDDPTLKGQGPSTPSQTAWALLGLLDAGSSSAAAESAIEKGIHYLVET
QTPEGTWDEQEFTGTGFPRHFYIRYHLYRHHFPLMALGRYQLSYVPGA
>A0A3M2FWK8|squalene-hopene cyclase|EC 5.4.99.17|Cyanobacteria bacterium J003|TrEMBL
MPTPLTTAIDPKQLQQAIRASQDFLFSQQYAEGYWWAELESNVTMTAEVILLHKIWGTEQ
RLPLAKVEQYLRNQQRDHGGWELFYGDGGDLSTSVEAYMGLRLLGVPETDPALVRARQFI
LVRGGISKTRIFTKLHLALIGCYDWRGIPSLPSWIMLLPEGSPFTIYEMSSWARSSTVPL
LIVMDRKPVYAMDPPITLDELYAEGRANVVWELPRQGDWSDVFIGLDRLFKLFETLKIDP
LREQGLKAAEEWVLEHQEPSGDWGGIIPAMLNSLLALRALDYAVDDPIVQRGMAAVDRFA
IETETEYRVQPCVSPVWDTALVMRAMVDSGVAPDHPALVKAGEWLLSKQILDYGDWHVKN
KKGQPGGWAFEFENRFYPDVDDTAVVVMALHAVTLPDENLKRRALERAVAWIASMQCRPG
GWAAFDVDNDQDWLNTIPYGDLKAMIDPNTADVTARVLEMVGRCQVAFDSGALDRALAYL
RNEQEPEGCWFGRWGVNYLYGTSGVLAALSLVAPPYDRWRIRRAAEWLVQCQNADGGWGE
TCWSYNDPSLKGQGDSTASQTAWAIIGLLAAGDATGDYAAEAIEKGIAYLLETQRPDGTW
HEDYFTGTGFPCHFYLKYHYYQQHFPLTALGRYARWRNLLAS
>A0A7V8VDQ5|squalene-hopene cyclase|EC 5.4.99.17|Thermogemmata fonticola|TrEMBL
MRGWHARSPEPSRWESGHAEEGWWEEVQQAQDQARRCLLAQQRPDGHWCAELQGDTILES
EFILLLAILGQRQDERIGRLANYIRRQQLPEGGWSTYPGGPADASVSVKAYFALKIAGDR
ADAPHMERAAAQIRQLGGAEAVNSFTRFYLAALGQIPYDACPTVPVELILLPRWFPINLY
AMSAWSRTIFVPLSLVNAYKPVTLLPETLHIRELFLTPPQQWRLTAKAPQGLLTWTRAFL
LVDRFLKFLERRGWTPWRRRAMERALDWMRQRWQDSDGLGAIFPPMVYHALVLHCLGKGP
DDPEMQAVLEQLAGLILEGEESLRVQPCLSPVWDTALAVHALAETGAEPEAVLSAARWLL
GREIRQPGDWAVRVREAEPSGWCFEYRNPYYPDVDDTAMVLLALARSGAAPEAGDTVARA
CRWLLAMQNRNGGWAAFDRDIENPLLEKVPFADHNAMLDPACPDITGRVLEALSHYGYRL
GHLAVDRAVQFLLARQEESGAWFGRWGVNYLYGTWQVLSGLRAVGFDLQHPAVRRAVRWL
KEVQNPDGGWGESCRSYDDPAWAGQGESTASQTAWAILGLLAAGEKDGPEVRAGIEFLLG
TQKAEGHWQETAFTGTGFPRVFYLKYHLYPLYFPLLALSRYARLARTPTPPPPPPPPPPP
PPPPPAATLSLDDGRRSSSRSGRANPEVMSCLHPQRFPHGGLMRFPLSLTADLTAYMLRQ
KLRRQRRFPLVLMLEPLHACNLTCTGCGRIREYESTIREKLSVEQCLESVDEAGAPIVSI
CGGEPLIYPHIGELVRGILKRRKHIYLCTNGVYLEKKLHLFRPTSRFFFNVHLDGLEETH
DRLVERPGVFRAAIAGIQAAKRAGFLVCTNTTVYRETEIAEIDALFAYLTELGVDGFLLS
PAYGYAAVHRTNPQGAAEIFLTRDEIRAKFQQAQHLFHKYKLTTSPIYWEFLQGKRELTC
AAWASPTRNVRGWKGPCYLITDAHYDSFQDLMENTPWENYGYGKDPRCEHCLMHSGYETA
AALGMNARLRDGWKMLLWQLT
>Q3ERU9|squalene-hopene cyclase|EC 5.4.99.17|Bacillus thuringiensis serovar israelensis ATCC 35646|TrEMBL
MHQAYLLRKQQTKKVDWSVHAPNLFPGGWGFSDVNTMIPDIDDTTAVLRALARSRGDENV
DNAWKRAVNWVKGLQNNDGGWGAFEKGVTSRILANLPIENASDMITDPSTPDITGRVLEF
FGTYAQNELPEKQKQSAINWLMNVQEENGSWYGKWGICYIYGTWAVLTGLRSLGIPSSDP
SLKRAALWLEHIQHEDGGWGESCQSSVEKRFVTLPFSTPSQTAWALDALISYYEKETPII
RKGISYLLSNPYVNEKYPTGTGLPGGFYIRYHSYAHIYPLLTLAHYTKKYRK
>A0A846TAY4|squalene-hopene cyclase|EC 5.4.99.17|Mesobacillus selenatarsenatis|TrEMBL
MRHRVMKEMDRIATQLIQDQSDDGAWRYPFETGIATDCSMIILLRTLEINDEEFIKELVK
RIAGQQQEDGSWKLFHDQEKGNLTSTVEAYYALLYSGYRDRKDKDMQAARRFIMANGGAS
EVHMFLKILLALTGQCEWPHLPINIEVMLIPDSFPINLFDLSVYGRANIIPFLILANTNF
RKRTPRSPDLSDLFQNKEVRFFTEEQEEETRSLIKWIKQGIQGMKYHGNLRELALYRAEK
YMLDRIEPDGTYLNYFSTTSLMIFALLARGYHTTHPVIIRAVQGLKAMTCRIDGELHCQY
TTATVWNTTLISYALQESGIPYSSSTVQKANHYILSRQHLKYGDWAIHEPDVLPGSWGFA
DLNTFHPDIDDTTAALRAIRTLATEQVDCRQAWDRGVNWLISMKNKDGGWAAFEKNVDKK
VLNLLPIEGGKDLLIDPSTVDLTGRTLEFFGNYTNLDEHHPMIKDGVRWLLRHQNSDGSW
VGRWGVYIYGTWAAVTGMIAVGVSPKHPAIQKAITWLRKIQNPDGGWGEFCKSDIKNSYV
PLGESTRTHTAWALDTLISAATGVTPEIENGAAFLADRKEKDWTSAYPKGRGMAGSFYIN
YHCYEYVFPLLALAHYQKLAGGELLTDK
>A0A7T4WC95|squalene-hopene cyclase|EC 5.4.99.17|Acidithiobacillus ferrivorans|TrEMBL
MNRILQPMHYGARIFRAPLDRVIAEARTALSSLQAEDGHWCFEFEADCTISAEYILMQHY
MDERDGPLEAKIAIYLRNKQADHGGWPLYYGGPFDLSASVKAYYALKLAGDNPDLPHMRR
AREAILAHGGAEHANVFTRITLALFAQVPWRAVPFIPVEIMLLPRWFPFNIYKVASWSRT
VMVPLFILCSLKARAKNPLQVHIHELFRRPPEQITDYFSHARQGIVAHLFLSLDRFWRLM
EDWIPQRIRCRAVQKAEMWFIARLNGEDGLNGIFPAMVNAHEALELLGYASDHVYRQQTR
AALRKLVVERASDAYCQPCVSPVWDTCLALHALLEQDGEVSPAVQSGIQWLKDRQIGAEP
GDWQEQRPNLAGGGWAFQYANPYYPDLDDTAAVGWALARAGRAEDRDSIERAANWLAGMQ
SSNGGFAAYDVDNTHYYLNEIPFADHKALLDPPTADVTGRVVAFLAHLARPRDRDILRRA
VAYLLREQESSGAWFGRWGTNYIYGTWSVLMALAELDDPSLQPAMERAAYWLRAVQQSDG
GWGENNDSYGDSGLAGMGQASTAAQTAWACLGLMAAGDQDSLALHRGMAWLQMHQEEDGR
WPDLFFNAPGFPKVFYLIYHGYSLYFPLWALARYRNLGCIAGD
>A0A5S4WP55|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium cytisi|TrEMBL
MDSVNATSREALESSTLESSIASATQGVLGLQQSDGHWVFELEADCTIPAEYILLRHYLA
EPVDTVLEAKIGNYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDSTDSPHMVRA
REAIHARGGAINSNVFTRFLLATFGVVSWRAVPVLPIEIVLLPFWSPFHLNKISYWARTT
MVPLMVIAALKPRAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFLLFRALDAILRVV
EPMFPKRLRQRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKDENFPPRAITR
RGIDKLLVIKSEEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLDWLIPKQELEV
KGDWAVKRPGVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGATGYDAAIDRGREW
IEGMQSDDGGWAAFDVDNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETAKTS
KHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVPHTDPMMRKAAGWLAS
IQNEDGGWGEDAVSYRLDYKGWEPAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIAT
QNEKGLWDESRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A4R4XT95|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. KC06|TrEMBL
MTAVEDTTGTRTAADAVEAAREHLLLLQSPEGWWKGELQTNVTMDAEDLLLREFLGIRDE
DDTREAARWIRSQQAADGTWANFHDGPPELSTTVEAYVALRLAGDAPDADHMARAAAYIR
GQGGVPATRVFTRFWLAMFGRWSWDELPVVPPELMFLPRWFPLNVYDFACWARQTIVPLT
VVGAVRPVRPLPFELDELYPDYDVPRPTRTTGWDAAFQALDKALHIYQRRPAKAVRRAAL
RRAADWIIARQERDGSWGGIQPPWVYSLLALHLLGYGLDHPIIQRGLDGLERFTIRDEKG
RRLEACQSPVWDTVLAMNALTDAGLPAGHPALERAAGWVIREEVKGPGDWSVRRPELPPG
GWAFEFDNDCYPDVDDTAEVVIALNRVQHPLAEPAIERGVRWMAGMVSKDGGFGAFDADN
TRTLCRRLPFCDFGEVIDPPSADVTAHVVEAMAHREMADSLLVKRAVGWLLKAQEPDGSW
FGRWGANHVYGTGSVVPALIAAGVRPEKPVIRDAVAWLERHQRDDGGWGEDLRSYRDRSW
AGHGASTASQTAWALLALLAAGERGESVERGVRWLVERQRPDGTWDEDHFTGTGFPGDFY
INYHLYRLVFPLSALGRYLKGS
>Q0RQT3|squalene-hopene cyclase|EC 5.4.99.17|Frankia alni (strain ACN14a)|TrEMBL
MSLTSDPSPAAPTAEKSPKRPTIPVPATADAYGISRSSPPLPAATGRPQAAGPASAGVAT
ARARDHLLALQSEEGWWKGDLETNVTMDAEDLFMKQFLGIRGDDETEQTARWIRSQQLAD
GGWPTFYGGPADLSTTIEAYIALRLAGDAVDAPHMARAAELVRAQGGVAASRVFTRIWLA
ALGQWSWDDVPVIPPELIFLPSWIPLNVYDFACWARQTIVALTIVGSLRPSHDLGFSIDE
LKVPAAARKPAALRSWEGAFERLDKLLHRYEKRPIKLLRTLALRRATEWVVARQEADGCW
GGIQPPWVYSVMALHLMGYPLNHPVIATAFRGMERYVIRRDTPQGPIRQIEACQSPVWDT
ALAVVALADAGVPGDHPAMVKAGRWLVDEEVRVAGDWAVRRPELAPGGWAFEFDNDFYPD
VDDTAEVVLALRRLLGAGHVAPPASRQGRAEAPPVNTVEDADPRLAAAMRAAAARGVDWS
VGMRSSNGAWGAFDADNVRTLTTKIPFCDFGEVVDPPSADVTAHIVEMLADLGRSDHPIT
QRAVQWLLDNQEPGGSWFGRWGVNHLYGTGAVVPALIGAGVPTDHPAITAAVRWLLEHQS
PEGGWGEDLRSYTDPAWIGRGELTASQTAWALLALLAVDPHSLAVKRGVRWLCETQRPDG
TWDEPYFTGTGFPGDFSLNYHLYRLVFPLTALGRYVSLTGVATP
>A0A6G2XHY4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8381|TrEMBL
MTATTDGSTGATLPTRAAAASEPVLTTPVAAGVHQAAEHAVRRATDFLLSRQDAEGWWKG
DLETNVTMDAEDLLLRQFLGIQDEATTHAAALFIRGEQREDGTWATFYGGPGELSTTIEA
YVALRLAGDAPDAPHMAKAAAWVRARGGIAASRVFTRIWLALFGWWKWEDLPELPPELIY
FPTWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAQPNPVKPLAPAAS
WDGAFQRLDKALHAFRKVAPKRLRRSAMNTAARWIIERQENDGCWGGIQPPAVYSIIALH
LLGYDLQHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQ
LVKAADWMLGEEIVRPGDWSVRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHD
PERVDRAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGLAHDPRTRRGIQWLLEEQEPDGSWFGRWGVNYIYGTGSVVPALTAAGLPGSH
PAIRRAVAWLKRVQNDDGGWGEDLRSYRDSKKWSGKGASTASQTAWALMALLAAGERDSE
AVERGVRWLADTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFAA
QAPAGRPLAEAKGS
>A0A3R9VIU3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. WAC07149|TrEMBL
MTATTDGGGAITGGADPRHDSTAAPAAAAAGPSGGGTGLRKGVREAVDRATGELLARQDP
QGWWKGDLQTNVTMDAEDLLLRQFLGIRDEAVTRAAALFIRGEQREDGTWATFHGGPPEL
SATIEAYVALRLAGDPPDAAHMSRASAWIRAHGGLAAARVFTRIWLALFGWWSWDHLPEL
PPELVFLPPWVPLNIYDFGCWARQTIVPLTVVSALRPVRPAPFALDELHTDARDPSPTKP
LPPLASWDGAFQRMDKALHLYRRVAPRRLRKAAMAAAGRWIVERQENDGCWGGIQPPAVY
SVIALHLLGYDLGHPVMRAGLESLDRFAVWREDGARMVEACQSPVWDTCLAAIALADAGL
PPDHPALVRAADWMLGEEIRRPGDWAVRRPGLAPGGWAFEFHNDNYPDIDDTAEVVLALR
RIRHPQPGKVEAAIARGVSWNLGMQSKNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSA
DVTAHVVEMLAAEGRASDPRARRGIAWLLAEQEADGPWFGRWGTNYVYGTGSVVPALTAA
GIAPSHPAVRRAVAWLESVQNEDGGWGEDQRSYRDRSWAGKGASTASQTAWALMALLSAG
ERDGEAVARGLAYLVETQRPDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHG
EPFGPERRSVPPAEES
>A0A371Z2W7|squalene-hopene cyclase|EC 5.4.99.17|Komagataeibacter melaceti|TrEMBL
MANTTETLTATRTSTDTTSGKADAAMPLDAASLEQAVTRAHAALGRRQADDGHWVFDLEA
DATIPAEYVLLEHYLDRIDPKLEQRIGVYLRRIQGTHGGWPLYEDGKFDLSASVKAYFAL
KAIGDSVNAPHMIRARQAILDHGGAERTNVFTRIQLALFGEVPWEAAPAMPVEIMLLPRT
ALFSVWNMSYWSRTVIAPLLVLAALRPRAINPRDVHVQELFVTPPAKVRDWIRGPYRSVW
GRVFKYVDAVLRPVESMIPEKTRRKAIKAAVDFIEPRLNGVDGLGAIYPAMANTVMMFRA
LNVPDSDPRAKTAWEAVQRLLVNQGEETYCQPCVSPIWDTGLAGHAMIEAASGPNGIAPE
ETKKKLAAAGKWLRERQILDVKGDWAINRPDLRPGGWAFQYANDYYPDVDDTAVVGMLLH
REGDPANTEAIERAREWIIGMQSTNGGWGAFDVDNNLDLLNHIPFADHGALLDPPTADVT
ARCISFLAQLGHPEDQPVIDRGVAYLRDDQEKDGSWFGRWGTNYIYGTWSVLCALNAAGV
AHDDPMIIRAADWLRSHQREDGGWGEDCASYEGAAPGTYKESLPSQTAWAVLGMMAAGLR
DDPAVARGVAYLGRTQGEDGEWAEEPYNAVGFPKVFYLRYHGYRQFFPLLALSRYRNMQV
SNSGRVGYGF
>A0A3M8CKH9|squalene-hopene cyclase|EC 5.4.99.17|Brevibacillus invocatus|TrEMBL
MVEWQKADGSWRFCLETSPMTDSHMIILLRTLSIDDEGLIEKLVSHIVSKQQDDGSWKLY
PDEPQGNLSATIDSYYALLFSGRYTKNEPRMALARSFIRERGGLTQANLLTKITTALTGQ
YQWPAHFIVPVELALLPPSLPVSFYDFVGYARVHLAPMMICADRKYVKKLPYTPDLSDLY
AVHPIAPGIYPHGILERFAKDGQALLSSTHDYVQRLPFLPGKLHEVGLRRLEQFMLSRIE
PDGTLYNYSTSTTLMIYALLARGYSSRDPVIQKAVAGLKASVCSQAAGVHLQLATSAVWD
TALSSHSLQRSGLSFSHPAISQANRYLLSKQQTTYGDWKIRNPGVKPGGWGFSDHNTMNP
DIDDTTAALRALHNQAKTDQLAAAAWNRGLVWLLSMQNDDGGWPAFEKNTDSALVRNLPI
EGADTVSTDPSTADLTGRTLEFLGRYAGMSVSDPRIARAISWLLANQQADGSWYGRWGIA
YVYGTWAALTGMIAVGLPPDYPAIQKAVLWLQRIQNPDGGWGESCLSDEKKTYIPLGAST
PSQTAWAVDALIAASPKPTPAVEHGIRFLTRRKPAGDWTSFYPTGGGRPGGTYFAYHSYQ
WIWPLLALSHYQDKYM
>A0A7V3BFT8|squalene-hopene cyclase|EC 5.4.99.17|bacterium|TrEMBL
MDHGNLPAALEPSLQCVSRRQGVDEPLAPAPITSRRSPIRSQPLSAEEAKRAVSREWIGR
VTEAIDRSRRFFLTSQAPEGFWVGELQSNVTITAEYIMFQYFLGRPERQRVDKAVRHLLR
TQQPDGGWNIYYGGPSELSATVEAYFALKLAGVSPNQPSMKMARKLILSLGGVEKSRVFT
KINLALFGQYSWEGIPSMPVEMMFLPTGFYFNIYEFSSWSRSVIVPLMIIFAKKPEVKLE
GFQGIDELYATPPDQRSMAVEWSEELVSWRNFFVLVDRLLKIVERRTPPAVRAAAVRRAE
QWILEHQDVTGDWGGIMPAMMNSVLALLSLGYQPTDPVIAKGLEAIERFGIETADEFWLQ
SCVSPVWDTAITIIALSDSGLDPMHPALTKAARWLLSKQVLRKGDWAIKNRRGQPGGWSF
EFFNDFFPDNDDTAMVLLALRLVRLPEEETLKEACQRGLAWLLSMQCDDGGWGAFDMNNN
KRLLNKIPFADLESLLDPSTSDVTGRIMELLGKLGYPPQHPVMRRALRFLRKDQTEEGAW
YGRWGVNYIYGTWAVLTGLRALGEDFSQDYIQHAIHWLESCQNPDGGWGESCYSYEDPRT
KGQGPSTPSQTAWAAMALIESGKATTPTVERAMRFLVERQQADGTWTEEEYTGTGFPKHF
YINYHLYRNYFPLMALARYRQALAGGTSG
>A0A6M8FZ44|squalene-hopene cyclase|EC 5.4.99.17|Arthrobacter citreus|TrEMBL
MDLDNIVIQNIEERIKRLRNRQEENGSWEFVFEGALLTDSFMILLMKDLGYENNQLIDGI
IDRIINLQHPNGAWKLYEDEKNGNLTATVQAYIALLVSKKYTKDHTSMKKAEKFIRENGG
IKKTHFMLKMILAIHGLIDYPKLFYFPMSYFLLPDKMPLSLFDLSNYARVHLVPMILCIN
KRFKVKLEDDLNIDNLLEDSEMEWFNEERGTFYQFILEEGKKLASYPLYFHQKGYEKAER
FILDRIETNGTFYSYASSTFYMVYALMALGYEVSSSVIQNALQGLLSYATNTDAGLHIQN
SRSKVWDTALLSYAIQEAGYSSNDPSVSKSIHYLISKQQDLIGDWSVHAKNLSPGGWGFS
DVNSFIPDNDDTGAVLRALSRSAMDQPNFQESWLKGVHFLLGLQNGDGGWGAFEKNVTNK
WLTHLPIENAKDAIIDPSTPDLTGRILEFIGNYTSISNDDPIVKKAADWLFKNQKSNGSW
YGRWGICYLYGTWAAITGLRAVGVSKNHEAIKKAEKWLVSIQNVDGGWGESGFSTVKGSY
IPLKYSTPSQTGWAIDALLTIRNKDDEVIKRGINYLVSQNEISNKALSYPTGLGLPGQFY
INYHSYNEIYPLLALAHFKNS
>A0A533S465|squalene-hopene cyclase|EC 5.4.99.17|bacterium|TrEMBL
MKPCKYPISNALTSFNGIAAENPEKENSKISAKVHHLPASIWKKRALENTTPLDVAIQRS
CDFFFREQLPEGYWWAELESNVTISAEYLMLFHFLGMVDKERERKLANYILSKQTAEGYW
SIYYQGPGDLSTTIEAYFALKLAGYPADHPAMEKARAFILKKGGIIKARVFTKIFLALFG
EFAWFGVPSMPIELSLLPKWAYLNMYEFSSWSRATIVPLSIVMATRPVRKLPPWARVQEL
YVRPPRPTDYTFTKEEGILTWKNIFIGVDHLLKIYERSPIRPFMKKAMSLSEKWVLDHQE
PSGDWGGIQPAMLNSILALNCLGYSNDHPAVQKGLDALANFGIESDDNIVLQSCISPVWD
TALALKGLIDAGVPTDHPALVKATQWLLDREVRKPGDWKVKSPELEPGGWAFEFLNDWYP
DVDDSGIVMMAIKNVKLKDSKSKDDAIERGIRWCLGMQSKNGGWGAFDKDNTKHILNKIP
FADLEALIDPPTADLTGRMLELMGTFGYPKDFPAAVRALEFIKKSQEPDGPWWGRWGVNY
IYGSWSVLCGLQAIGEDPAQPYIQKAVTWLKAKQNSDGGWGETCESYHDKDLAGVGESTP
SQTAWALLALMASGERKSDTISRGINYLIQTQQPDGTWNEDQFTGTGFPKYFMIKYHIYR
NCFPLMALGQYRGLLEDID
>A0A5B9GJE2|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter oryzoeni|TrEMBL
MNMASRFSLKKILRSGSDTQGTNVNTLIQSGTSDIVRQKPAPQVPADLSALKAMGNSLTH
TLSSACEWLMKQQKPDGHWVGSVGSNASMEAEWCLALWFLGLEDHPLRPRLGKALLEMQR
PDGSWGTYYGAGCGDINATVESYAALRSLGYAEDDPAVSKAAAWIISKGGLKNVRVFTRY
WLALIGEWPWEKTPNLPPEIIWFPDNFVFSIYNFAQWARATMMPLAILSARRPSRPLRPQ
DRLDALFPEGRANFDYELPTKEGRDVIADFFRLADKGLHWLQSSFLKRAPSREAAIKYVL
EWIIWHQDADGGWGGIQPPWVYGLMALHGEGYQFHHPVMAKALDALNDPGWRHDKGDASW
IQATNSPVWDTMLSLMALHDANAEERFTPEMDKALDWLLSRQVRVKGDWSVKLPNTEPGG
WAFEYANDRYPDTDDTAVALIALASCRNRPEWQAKGVEEAIGRGVRWLVAMQSSCGGWGA
FDKDNNKSILAKIPFCDFGEALDPPSVDVTAHVLEAFGLLGLPRDLPCIQRGLAYIRKEQ
DPTGPWFGRWGVNYLYGTGAVLPALAALGEDMTQPYISKACDWLINCQQENGGWGESCAS
YMEVSSIGHGTTTPSQTAWALMGLIAANRPQDYKAIAKGCRYLIDLQEEDGSWNEEEFTG
TGFPGYGVGQTIKLDDPAISKRLMQGAELSRAFMLRYDLYRQLFPIIALSRASRLIKIGN
>A0A2Z3NCS4|squalene-hopene cyclase|EC 5.4.99.17|Geobacillus thermoleovorans|TrEMBL
MVADERSTLIAVLKRSQAADGSWRFPFETGISTDAYMIILLRTLEINDEPLIQALVKRIE
SRQGANGAWKLFADEGDGNVTATTEAYYALLYSGYRKKTDPHMQKAKMRILEMGGLENVH
LFTKVMLALTGQYPWPRRFPLPLAFFLLPPSFPLNMYDLSVYGRANMIPLLVAAERRYSR
KTAKSPDLCDLAASRGGWRLPENRALWSYIKRALIGFPAELHDAAKRRAVRYMFDHIEPD
GTLYSYFSSTFLFIFALLALGYPKDDPHIVRAVRGLRSLRTEIDGHTHMQYTTASVWNTA
LASYALQEAGVPPTDRTIEKANRYLLSRQHIRYGDWAVHNPYGVPGGWGFSDVNTMNPDV
DDTTAALRAIRRAADKETAFRHAWDRANRWLFSMQNNDGGFAAFEKNVGKRFWRYLPIEG
AEFLLMDPSTADLTGRTLEYFGTFAGLTKDHSAIARAVDWLLDHQKADGSWYGRWGICYV
YGTWAAVTGLSAVGVPIDHPAMQKAVRWLLSIQNDDGGWGESCKSDEAKTYVPLGASTPV
HTAWALDALVAAADRPTAEIKAGVRALVRMLHHPDWTASYPVGQGMAGAFYIHYHGYRYI
FPLLALAHYEQKFGPFVD
>A0A7S7W0B9|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. CCBAU 53351|TrEMBL
MDSVTATSREALESSIASATQGVLDVQQSDGHWVFELEADCTIPAEYVLLRHYLAEPVDV
ALEAKIASYLRRIQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDSVDAPHMVRAREAIH
ARGGAINSNVFTRFLLAMYGVVTWRAVPVLPIEIVLLPFWSPFHLNKISYWARTTMVPLM
VLAALKPRAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFVLFRALDGILRVVEPMFP
KSLRKRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKDENFPPRAITRRGIDK
LLVIHDDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLDWLIPRQELEVKGDWA
VKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGATGYDAAIARGREWIEGMQ
SDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETAKTSKHVAD
GVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNVAGVDHGDPMIRKAADWLASIQNED
GGWGEDAVSYRLDYRGWEAAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIATQNEKG
LWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A537R0D5|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MQRIASALCHDPGNDGESQKPADRQSGVARARSQRCDRPLGRLEHYLGTPEPDIERRIAR
YLRAAQGPHGGWQLFYGGQFDLSASVKAYFALKAAGEPLDAPHMERARAAILAHGGASRC
NVFTRILLALFGEVPWNAVPVMPVEIMLLPGWFPFHVDKISYWSRTVLVPLLVLMALRPK
ARNPHGIRIPELFVEPPETVRDWISPPTPSVTGHAFALLDRLVRLGEPMFPAERRRRAID
KAVAFVTERLNGEDGLGGIFPAIANSLMMFDCLDYPPDHPDRVTAAAALRKLVILDGEQG
YCQPCLSPVWDTALACHALMEAGEARLTAPVRQALDWLADKQVLDTVGDWAAVRPGLRPG
GWAFQYANPHYPDLDDTAAVALALDRFDAERYETAIDRAAEWVLGMQSRNGGWGSFDADN
THYYLNHIPFADHGALLDPPTADVSARCLGFLAQRGLPNDHPAITGVLAFLRREQEADGS
WFGRWGTNYIYGTWSVLAALNAAGIDPESAEIRRAVAWLLSHQRADGGWGESGESYWPDE
PHGEAPYSTASQTAWALLALMAAGEVAHPAVARGITYLIETQDRDGNWDEPWYTAVGFPR
VFYLRYHGYRAFFPLFALARYRRLSLANSRRVVYGL
>A0A537MSQ5|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MQLKSHSMAADADALETSIASATSALLGYRQGDGHFVFELEADCTIPAEYVLLRHYLGEP
VDAVLEAKIANYLRRVQGAHGGWPLVHDGALEMSASVKSYFALKMIGDPIDAPHMVRARE
AILAHGGAIHSNVFTRFMLAMFGVMSWRSVPVLPVEIMLLPMWSPFHINKISYWARTTIV
PLMVLAALKPRAKNVSGVGIDELFLQPPHSIGMTAKAPHQSPGWFLLFRALDSVLRVIEP
LFPKKLRARAIDAAVAFIEQRLNGEDGLGAIYPPMANTVMMYEVLGKPADYPPRATTRRA
LDNLLVIREHEAYCQPCVSPVWDTALTCHALIEAGGERALPEAKQGLDWLKPRQVLDLKG
DWAVKSPTTRPGGWAFQYNNAYYPDLDDTAVVVMAMDRERRQSGSNEYDMAIARGREWIE
GMQSRDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCLAMLAQLGETTETSPA
VARAIEYLRRTQHAEGSWYGRWGMNYIYGTWSVLCALNAAGVRHQDPMIRKAAAWLVSVQ
HKDGGWGEDAVSYRLDYRGMEAAPATASQTAWALLGLMAAGEVENPAVVRGVEYLKATQA
QNGLWDEARFTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNSRVVGVGM
>A0A0E3PM08|squalene-hopene cyclase|EC 5.4.99.17|Methanosarcina siciliae C2J|TrEMBL
MTNEQVLNGRILSNRILNDRVSDNRTLNDKISGNKIFDNRMLNAVELAVGKARNFIISNQ
SGEGYWLDFYIPGMGNSSQWVTAYIAYNLSRLPNTDESVQKAIVWLLHTKSSSGWGYHQN
CLPDADSTANVVRLLAYYFKKENLLTQENFAFYLHEFAYLLASYQDKNTGGFLTYLPGSN
GKYHTMPDSAWCISEPSITAMAGNAFLNSGPEWVEQEISNAREFLISRQNPAGYWDSYWW
DCRIYGTSLACSFLKQLGEIDPVKKAISWIESVFVPSKGWGNGYEADPYPFYTALSLSSL
LLFENNIHSREVKDSVLWLIENQNEDGSWFSKSILRVPDPQVREPWAGSNRRKCEVVTDV
NLLFTTATVMGVLYDFLNLSGYYSCSASQE
>A0A5Q4ESM4|squalene-hopene cyclase|EC 5.4.99.17|Phycisphaeraceae bacterium|TrEMBL
MPTPPPGPSGDAPAVTTTATATPADHRAARALQPSTSPGTRIDTDTVARALDRAVDALFT
KQRADGHWCAELEGDSILSSEYLLMKAILGQRSPDDAEGSPADTPEKFEKICAYLRALQR
TGGAWGQYPGSGPDVSATAKAYLALKIFGDDPKSPHMRAALEATHRLGGAEKINTFSMFY
LACLGQVSWKACPTIPPEVVFLPRWFPFHMDKVAAWTRTMILPLALCTALRPVRTLPDHL
GCAELFIDPKSRTRLNKPWNTKDPTCWSNIFLGIDRFLKFVHAARLSPVRSASIRAARDW
IVERMRADTTDGLGAIFPPMVYIQVALHKMGYERSHPVRAEAERQLDRFIVEKDDHIRIQ
PCFSPVWDTGIALYALTEAGLTAQDDDRIARTCAWLCDREVKLVGDWVRNLRAADRERFR
ADRDSWAAWAFEYRNDWYPDVDDTAMVAKAMRRAADGLPPGHRFADTARRATEWIVAMQN
DDGGWAAFDRTKHREWMEAVPFADHNAMQDPSCPDITGRTIEALITCGVPRDHASVRRAV
EYLKTTQLPEGCWKGRWGVNYLYGTWQAVGGLDAAGEDVRQPYLQRTLTWLRKVQNEDGG
FGESANSYENESIKGVGPSTASQTAWGVTTLMYLTSPNDTAVLRAIRWLVDHQLDADTPA
APWPVQVEGEDWKLGLIEQSEKTAPKANHLVDEPAGAWREPWFTGTGFPKVFYLRYHLYR
HYFPVMALGRWVRLTGVRPTHSGNQV
>A0A7C9VDD5|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Afipia apatlaquensis|TrEMBL
MTLEDHKAGAAAPSAAAVDASIAAASSAVLDYRKPDGHWVFELEADATIPAEYVLLRHYL
AEPIDTVLEGKIANYLRRIQNENGGWSLFYGHEFDMSASVKAYFALKMIGDSPDAPHMKK
AREEMLRRGGAIKSNVFTRIMLALFGVVTWRAAPMMPVEIMLLPRWFPIHLTKISYWART
VIVPLLVLMNKKPRARNPLGVGIDELFLEDPKSIGMTAKAPHQSQLWFTGFNLLDKVLRV
VDPLFPKAPRQHAIDKAVAFVTERLNGVDGLGAIFPAMANTVMMYDLLGYPKDHPHYVLA
RQSIENLLVIKDDEAYCQPCVSPIWDTALTAHAMIEVGGEKEVASAKAALDWLKPKQVLD
VEGDWIEKRPGVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRARGTLNAGTKYDESIARGR
EWIDGLQSKDGGWAAFDADNLEYYLNNIPFSDHGALLDPPTEDVTARCVSMLAQLGETVK
TSEALARGVEYLRRTQLPDGSWFGRWGVNYIYGTWSVLCALNAAGVDHADPVMAKAADWL
IAIQNSDGGWGEDGNSYRLDYRGYEKADSTASQTAWATLALMAAGKVDHPATQRGIAYLI
EFQGKDGLWSEPQYTGGGFPRVFYLRYHGYSKFFPLWALARYRNLRNTNSRFVGIGM
>A0A5C1YMD5|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter sp. KACC 21233|TrEMBL
MPADGSALSDTPLSRDDLDRAVRNAHATLAGAQQGDGHWVYELEADATIPAEYILLEHFL
DRIDDALEQKMAVYLRRIQSDVHGGWPLYHNGDFNISASVKAYFALKAVGDDINAPHMRR
AREAILDHGGAERTNVFTRFQLALFGDVPWRATPVMPVELMLLPRSAFFSVWNMSYWSRT
VIAPLLVLAALRPVAINPRQIHVRELFVTPPEKVTDWIRGPYRSSWGYVFKGLDVALRPL
VPLIPSKTHQKAIKAAIDFIEPRLNGRDGLGAIYPAMANVVMMYRAMGVADTDPRAATAW
EAVQNLVVEKDDEAYCQPCVSPIWDTGLSGHAMIEAASGPNGVAPAETLEDMKKACAWLR
SKQILDVKGDWAINNPNLAPGGWAFQYGNDYYPDVDDTAVVGMLLHREGDPASAEAIERA
RQWIIGMQSTDGGWGAFDIDNNKDLLNHIPFADHGALLDPPTADVTARCISFLAQLGNPE
DAAVIQKGLDYLRKEQEADGSWFGRWGTNYVYGTWSVLCAFNAAGISHDDAAVVRAVEWL
RAMQRPDGGWGEGCESYENGPRGTYGESLPSQTAWAALGLMAAGRRDDPAVSRAMSWLAD
QQDETGAWHEDPYNAVGFPKVFYLRYHGYKQFFPLMAMARYRNLESSNTRRVGFGF
>A2RZU1|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia mallei (strain NCTC 10229)|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANAMRVTVGM
>Q0AFY0|squalene-hopene cyclase|EC 5.4.99.17|Nitrosomonas eutropha (strain DSM 101675 / C91 / Nm57)|TrEMBL
MSISQAFFRTLIQKSSLSDSSLVSENFPADDVAGNEANEISAVTLDEAITRAYTALLAQQ
REDGHWCFPLEADCTIPAEYILMMHFMDEVDTVLERKIANFLRTRQVTDGHGGWPLYYGG
DFDMSCSVKTYYALKLAGDSPEAAHMVHARNAILERGGAARSNVFTRLLLAMYRQIPWRG
VPFVPAEIMLLPRWFPFHLSKVAYWSRTVMVPLSILCTLKAKAINPRNVHVQELFVVDPV
KEKNYFPVRTSLNRLLLYVERLASKLEPFIPSFIRRRAVKKAEQWVIERLNGNDGLGAIF
PAMVNAYEALTLLGHDRDHPLLQQCRQSLRELLVDEGEEITWCQPCVSPVWDTVLATLAL
QEDKQADSEPIRRALDWIVPLQILDEPGDWRDSRPNLLGGGWAFQYANPHYPDLDDTAAV
AWALIQTGAEDYRVSITRAADWLAGMQSSNGGFAAFDIDNAYYYLNEIPFADHGALLDPP
TSDVSARCVGLLALNGEVRHQEAVKRGLDFLFNEQESSGAWFGRWGSNYIYGTWSVLEAF
RLARVDKGHQAVQRAIQWLESVQRADGGWGETNDSYLDPQLAGQLEASTSFQTAWAVLGL
MAAGEVENTAVRKGIDYLLRTQIATGLWEEPWFTAPGFPRVFYLKYHGYSKYFPLWALNR
YRTLSSKSAV
>V5DL20|squalene-hopene cyclase|EC 5.4.99.17|Methyloglobulus morosus KoM1|TrEMBL
MFTDAQTDTQTQNLGSAATPIVFRDGQLEAAINKAQDKLLSLQDKRGYWVFDLEADCTIP
SEYIMMMHYLDEIDEPLQAKIAVYLRSRQSKDGSYPLFTHGPGDISCSVKVYYALKMAGD
SVDAPHMTSLRDWILQQGGAAKANVFTRIALAIFKQLPWRGVPFIPPEIMLFPKWFPFHL
DKVSYWSRTVMVPLFILCSLKATAKNPNKIDVLELFVTHPDEERHYFPERTLLNKIFLGL
DKFGRWAEPFIPTQIHDRAIEKAKDWIVERLNGEDGLGCIFPAMVNSYESLLLLGYPKDH
EYIVTARKAIDKLLVITDDMAFCQPCVSPVWDTALTALALQEVDKQANASSLTKAYDWLK
SVQLSDEPGDWRVSRPHLAGGGWAFQYANPHYPDVDDTAVVAFAMADSNLPNLDESIHRA
TRWIEGMQSKNGGYGAFDVDNTYYYLNEIPFADHGALLDPPTADVSARCAMLMAKAGKES
GMYQAALERSINYLRSEQEKDGSWFGRWGTNYIYGTWSVLLGLEQTNLPKTDVLYLNAVK
YLKAKQREDGGWGEDNYSFHDVSYSGKYHFSTAFQTAWAVLGLMAAGEARSAEVKAGIDF
ILRNQQADGVWNDPCFTAPGFPRVFYLKYHGYDKFFPLWALARYRNELDKQ
>A0A4S4BW78|squalene-hopene cyclase|EC 5.4.99.17|Metabacillus sediminilitoris|TrEMBL
MKYKIETEINRLVNILIKEQEPNGSWTYPFETGITTDCYMIILLRTLEINDEDFIQSLVD
RIISKQDENGSWKLFYDEEEGNLTATVEAYYALLYSGYCTKTDSNMRLARNFIINNGGLK
EINMFTKVMLALTGQYKWPEHFPIPVEIVLLPLSFPVNFFDFSVYARVNFIPIVIAADYK
FSMQTKRTPDLSELFLQRGDDDWEKEINEWRSFLSTIHIGIKSLIGLPHELHRIALNHAE
QYMLQRIESDGTFYSYFSSTFLMIFALMAHGYSKQHPIITKAIKGLKSNQTRIDDHLHIQ
YTKATVWNTALISYSLQEAGISSSSETIKKAQQYLISKQHYLYSDWAIHNQHALPGGWGF
ADINTMHPDIDDTTASLRAIRSLILSNPVYRQAWDRANHWIISMQNDDGGWAAFEKNVNK
SFLSWLPVEGGTAMILDPSTADLTGRTLEYFGNFTRLNKNHPFIKRGIEWLLRNQEKDGS
WYGRWGICYIYGTWAAITGLVAVNTRNDHPAIQKAIRWLYRIQNPNGGWGESCKSDIHKK
YISLNESTRTHTAWALDTLISAENEETVEINRGITYLLESSHKNDWTTTYPKGQGLPNGF
YMHYHSYEYLFPLLALSHYKNKFFK
>A0A2X3KTN9|squalene-hopene cyclase|EC 5.4.99.17|Frankia sp. Ea1.12|TrEMBL
MSLTSDQSSAAPTAAAQSPKIPNPSVARPSVDAGSFETAGAVRTDSLSIDSVSTGTVSTG
TPVDPVVGAMRRGRDHLLSLQAEEGWWKGELETNVTMDAEDLMLRQFLGILTPSTATETG
RWIRSQQLSDGGWATFYGGPSDLSTTIEAYVALRLAGDDPDAPHMRSAAEWVRSAGGIAA
SRVFTRIWLALFGEWSWDDVPVLPAEMTFLPPWFPLNIYDFACWARQTVVALTIVGSLRP
VRSFGFTLDELRVPAPKAARAPLRSWAGAFERLDSVLHRYEKRPFQPLRRLALRRAAEWV
IARQEADGCWGGIQPPMVYSIMALHLMGYPLNHPVISMAFRALDRFTIREETPEGTVRRI
EACQSPVWDTALAVVALADAGLGGDHPAMVRAGRWLADEEVRVAGDWAVRRPTLAPGGWA
FEFDNDFYPDVDDTAEVVIAIRRLLGDGHGPVDHSDGSGPGSAAATAASAAAEAAVAAAG
TIAAADPELAARLRAAAERGVDWSVGMRSSNGAWAAFDADNVRTLVTKIPFCDFGEVVDP
PSADVTAHMVEMLALLGRSDHPITQRGVRWLLDNQEAGGSWFGRWGVNHVYGTGAVVPAL
ISAGVSAEHPAIVSSMHWLVEHQTPEGGWGEDLRSYRDDEWIGRGEPTASQTAWALLALL
AAEPASGTAEWEAVERGVRWLCDTQRPDGTWDEPQFTGTGFPWDFSINYHLYRLVFPVTA
LGRYVTLTGRSTS
>A0A160V6Y8|squalene-hopene cyclase|EC 5.4.99.17|hydrothermal vent metagenome|TrEMBL
MAQLKHSDVNQAADKAVQRSQDYFRRTQYPEGYWWGELESNPTMEAEYLMLCHFTGRHDQ
ERWRKICNYILSKQRSDGSWSQYYEAPGDVSTSVECYFALKLAGHSPDTEPLRKAREFIL
SKGGIPKVRVFTKIWLALFGQWDWKGTPNMPPEMIFLPSWAPFNIYEFASWARATVVPML
IILTRQPYCAVPESADIGELYPGGREGTDYHLPKPTGGFGWSKALYWADKLVGLYQRLPV
HPFRGRAERKIIQWVLDHQEADGSWAGIQPPWVYSLITLHTLGYGPDHEAVKKGFQGFER
FALEDEDKCNVQACISPVWDTCIAQLALLESGIDPEDPMVQSSARWLMDKQIYATADWQI
RAKGTRPGGWSFEFDNLIYPDVDDASIVVMALDQVRLPEAEEPRRADSIQRGVEWMAGMQ
SKNGGWAAFDKDNNKKYLTKIPFSDFGETLDPPSVDVTAHLLEMYGRLGYTKENRAVDRG
FAYVVSEQEEDGSWFGRWGVNYVYGIGAVLPALEAIGEDMSQAYIRLAVDWTVAHQNQDG
GWGESCGSYVDPNLHGVGPSTASQTAWALLGLVAAGEHESEAAQRGLVYLAETQLEDGTW
DEPYFTGTGFPGYGVGERLKAMPDIGELSYQDLDMPAGFMINYHLYRNYWPLLALGRYSQ
AVSGRL
>A0A3B0RQF8|squalene-hopene cyclase|EC 5.4.99.17|hydrothermal vent metagenome|TrEMBL
WALMGLAAANRREDREAIERGVVFLMERQKDGTWQEPEYTGTGFPGYGVGATIKLGDPLL
TERLKQGPELSRAFMINYNLYRHYFPLMAMGRVRKILA
>A0A7J4ZLZ6|squalene-hopene cyclase|EC 5.4.99.17|Oryzomonas japonica|TrEMBL
MNSSKYPISTALTSFNLETAAPTAPALDPPKKTVAKVHHLPPSIWKKMVGDAKSPLDKAI
ERTRDFFFREQLPDGYWWAELESNVTITSEYVMLFHFLGMVDKVRERKMARYILSKQTEE
GYWAIWHTGPGDLSTTIEAYFALKLAGYPADHPAMRKAREFILANGGIIKARVFTKIFLA
LFGEFSWLGVPSMPIELMLLPNWAYFNVYELSSWARGTIIPLSVVMAERPVRKLPPWARV
KELYVRPLRPTDYTFTKEDGILTWKNFFIGVDHLCKVYESSPIRPFKKKATSVAEQWILD
HQEPTGDWGGIQPAMLNSILALHCLGYANDHPAVVKGLEALANFCIEDEEGLVLQSCISP
VWDTALALVAMQEAGVPADHPALVKAAQWLLDLEVRRKGDWQIKASELEPGGWAFEFLND
WYPDVDDSGFVMLSIKDIKVRDRKHKEQAIKRGISWCMGMQSQNGGWGAFDKDNTKYLLN
KLPFADLEALIDPPTADLTGRMLELMGNFNYSKSHPAAEHALEFLQKEQEPEGPWWGRWG
VNYIYGTWSVLCGLQAIGEDMSLPYVKKAVNWFKSKQNMDGGWGEVCESYFDRSLMGSGP
STPSQTGWALLALMAAGEVHSKTVARGIDYLLNTQKQDGTWDEDAFTGTGFPKFFMIKYH
IYRNCFPLTALGKYRRLLAEGGEKK
>A0A536TRC1|squalene-hopene cyclase|EC 5.4.99.17|Betaproteobacteria bacterium|TrEMBL
MHSSSREARLTPDPELVARQIPIGPAESSLDRAIETATAALVKRQRADGHWVFELEADAT
IAAEYVVLQHFLGEPNPALEAKIAIYLRRLQGPHGGWSLFHGGGLNISASVKAYFALKLA
GDAPESAHMRRAREAILAQGGAGTTNVFTRILLALFGVISWGAVPIIPVEIVFLPRWFPF
HLSRVSYWSRTVVVPLLVLQALKPRARNPRGVRIDELFPGRRPRARRWARAPHQARARFA
VFAAIDAALRLVEPLIPQRLRRRAIKKAVAFVTERLNGEEGLGAIFPAMANTVMMFDALG
YARDHPHFVTARRAIDKLLVVTREEAYCQPCVSPVWDTVLVCQSLLEVGDNQTRTAARDG
LAWLEKRQVLDAVGDWADQRPHVRPGGWAFQYANPHYPDLDDTAVVVMAMDRFARRRVMR
GEPDFRGAIDRGREWVLGLQSANGGWGAFDV
>A0A6N6PZS5|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia bacterium|TrEMBL
MSSSPVPLAPASDPSKSPVLPAGAVAGLDEAITRSQSYLLSELKPEGYWIGELIVDVTLV
ADMVVFYHWWGKVDPAWQAKAVHHIFSKQLADGGWNIYPHGPSEVNATVKAYLALKLAGI
DPKDPRMLRAREVACTLGGVPRMNTFSKLYLALIGLVTWKHVPTIPSEVLLIGKWFHVNF
WEMSSWSRAMLVPLAIINHFRPTRPLPLNVDELFPNGKWELDEALRPRYFDFGLRNMFLW
LDRLHKLAEWFSRHGLHPFRRRALRRAETWMLERFEGSDGLAAIFPAMLNALIALKALGY
DDEHPQVVRAHRELLRLMHETADSVRIEPCLSPVWDSAIVSICLRESGVPANHPKMVKST
HWLMDREIRFKGDWIHKNPVDVEPSGWVFEFNNQWNPDVDDTAMVLLALRQTPTDNPRRR
DESFARGLKWMMAFQCRDGGWAAFDKDCTKSILEKVPFADHNAMLDPECADITARILELL
GYEGWDVNHPQIKRALDYLRAQQEPDGSWYGRW
>A0A6B3QHA2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces tendae|TrEMBL
MTATTDGSTGASLRPLAASASDTDITIPAAAAGVPEAAARATRRATDFLLAKQDAQGWWK
GDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDAPDAPHMARAAEWIRSRGGIASARVFTRIWLALFGWWKWDDLPELPPELI
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPARPNPPRPLAPAA
SWDGAFQRIDKALHAYRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPEDHP
QLVKASDWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHH
DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAVEGLAHDPRTRRGIQWLLDAQEADGSWFGRWGVNYVYGTGSVIPALTAAGLPTS
HPAVRRAVRWLESVQNEDGGWGEDLRSYRYVREWSGRGASTASQTGWALMALLAAGERES
KAVARGIQWLAATQREDGSWDEPYFTGTGFPWDFSINYNLYRQVFPLTALGRYVNGEPFA
KKSRASEAPAESAAAEVKGS
>A0A1I9YNW9|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia sprentiae WSM5005|TrEMBL
MNDLSQPQPLDAVLPEAADAALNPAEAAVVANAPAVADALATATPAPVQGDGASTLDASI
TRATDAILAAQQPDGHWVYELEADATIPAEYVLLVHYLGETPNIELEQKIARYLRRIQLP
NGGWPLFTDGALDVSASVKAYFALKMIGDPVDAEHMVRARDAILAHGGAEHANVFTRILL
ALFGVVSWRAVPMMPVEIMLLPMWFPFHLSKVSYWARTVIVPLLVLNAKRPLARNPRKVR
IDELFRGAPVNTGMNERAPHQHAGWFGFFRCVDTVLRAVDGLLPKATRERAIRAAVAFVD
ERLNGEDGLGAIFPAMANSVMMYDVLGYPADHPHRAIARKSLDKLLVIKDDEAYCQPCLS
PVWDTSLAAHALLETGEARAEQAAERGLAWLRPLQILDVRGDWISRRAHVRPGGWAFQYN
NAHYPDVDDTAVVAMAMHRSAALTQSDVDHEAIARAREWVVGMQSSDGGWGAFEPENTQY
YLNNIPFSDHGALLDPPTADVSGRCLSMLAQIGELPQSSEPARRAFDYMLQEQESDGSWY
GRWGLNYIYGTWTALCSLNAAGMPHDDPRMRRAVQWLVSIQNEDGGWGEGGESYKLDYRG
YERAPSTASQTAWALLGLMAAGEIDHEAVARGIDYLQREQREHGLWDETRFTATGFPRVF
YLRYHGYRKFFPLWALARFRHLKRKGLTRVTVGM
>A0A6P0VU45|squalene-hopene cyclase|EC 5.4.99.17|Symploca sp. SIO1A3|TrEMBL
MQTQDSITTESTESIAEAIAKTQNYLLNLQYPEGYWWAELESNVTITSEVVLLHKIWGTD
QARPLHKVEAYLRSQQREHGGWELYYGDGGDLSTSVEAYMALRLLGVPATDPALLKAKKL
ILERGGISKTRIFTKFHLALIGCYDWRGVPSIPPWVMLLPEQFLFSIYEMSSWARGSTVP
LLIVFDHKPVYQTNPAITLDELYTEGASNVRFELPRNGDWTDLFVTLDDTFKLAEDLDFV
PFRQEGLEAAERWVLERQEVTGDWGGIIPAMLNSLLALRSLNYDVTDSVVVRGLEAVDNF
AIETAETYTIQPCISPVWDTAWVIRALVDSGIAPDHPAVVQAGEWLLSKQILGYGDWAVK
NPQGKPGGWAFEFENRFYPDLDDSAVVVMALDAVQLPQEDHKRTAIARAVAWMASMQCQE
GGWAAFDINNDADWLNYLPYADLKAMIDPNTADVTARVLEMLGSCNLSIEQSKLERSLTY
LLEEQEADGSWFGRWGVNYIYGTSGALSALSVITPEKHRLSIEKGANWLVGCQNTDGGWG
ETCRSYDDPKLKGQGDSTASQTAWALIGLMAAGEATGNGATEAINRGINYLVTTQLPDGS
WNEDYFTGTGFPSHFYLKYHFYQQYFPLIALGRYLK
>A0A7C4LRJ0|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MTTQSIQGATSEGNLPSNGLAGLADALRRSQDYLLRAQKPEGYWVGELMVDSTLVSDMVA
YHHWDGKVDPEWQRKAVNHILSMQLPDGGWNIYYGGPSEVNATIKAYLALKLAGVPVTDP
RMLRAREIAKNLGGVPRMNTFSKLYLALLGLFPWKYVPTIPCEVILLGKWFHVNFHDMSN
WTRAMLVPLAIINHFKPTRSVADWASLDELYPEGHQEHELALPPAPKFFAWRNFFLWLDK
LHKFAELWARAGIHPFRRMALKRNEQWMLERFEGSDGLAAIFPAMLNSLIALKALGYPDD
HPQVVRAERELKKLEHEEADSVRIEPCFSPVWDTVITLICLRESGVPADHPQIKKAAEWV
MDREIRFKGDWIHKNPADVEPSGWVFEFNNKWNPDVDDTAMVLLALRLIPTDHPRRRDEC
FQRALKWMLTFQCRDGGWAAFDKDCTKSVLTKVPFADHNAMLDPECADITARILELLGYE
GFPLDHPQIQRALQYLKDQQEDDGSWFGRWGVNYIYGVWQVARGLAALGYNMNEPWLLRA
RDWLESVQHADGGWGERCNTYDDPVFKGQGPSTASQTAWAVMGLLAFGDPDRPSIRRGLE
YLIRTQNPDGSWTEMETTGTGFPQVFYLKYDMYRNTWPLLAMATYRNLREGRRPGTKSA
>A4JKI8|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia vietnamiensis (strain G4 / LMG 22486)|TrEMBL
MNDLTDMANLSAGTVPAGLDASVARATDALLAAQNADGHWVYELEADSTIPAEYVLLVHF
LGETPNLELEQKIGRYLRRIQQADGGWPLFTDGAPNVSASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALFGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIGELFIDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AADGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYPEDHPNRAI
ARKSIEKLLVVHDDEAYCQPCLSPVWDTSLVAHALLETGDARAEQAVLRGLDWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLQNTDTYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQLGESAL
SSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLGPEDPRVKRAAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEPAPSTASQTAWALLGLMAAGEVNHPAVERGIGYLI
AQQNDEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGI
>A0A5N0V302|squalene-hopene cyclase|EC 5.4.99.17|Amycolatopsis acidicola|TrEMBL
MTLTTEPGVRTPAETLERAVAHLKGRQETGGWWKGELETNVTMDAEDLLLREFLGIRTAR
ETEEAARWIRSQQREDGTWATFYGGPGDLSTTVEAWVALRLAGDSPDAPHMRAAQEFVLD
GGGLEASRVFTRIWLALFGLWSWDELPNMPPELIFLPSWFPLNVYDWGCWARQTVVPLTI
VGTLRPVRPLSFGVDELRTRQRKRTLIKPWTWSGAFEMLDLGLKAYARLPVKPLRGLAMR
QAAEWILARQEADGSWGGIQPPWVYSLLALHLLGYSFEHPAMKAGLKGLDGFIIREETPD
GRVRRLEACQSPVWDTALALTALLDADVPADDPAVLKASDWLLGEEITVKGDWAVKRPAT
PPGGWAFEFANDVYPDTDDTAEIVLALRRVAHPDRPRLKDAVERAVTWLNGMQSADGGWG
AFDADNTRTLTTQLPFCDFGAVIDPPSADVTAHVVEMLAAEGLTGTKECRRGVAWLLAAQ
EKDGSWFGRWGANHLYGTGAVVPALVAAGVSPQASPIRRAVEWLAEHQNPDGGWGEDLRS
YREPEWIGRGDSTASQTAWALLALLAAGERDSSIVERGVGWLARTQREDGTWDEPQYTGT
GFPGDFYINYHLYRLVFPVSALGRYLEAS
>A0A6N8YSA4|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MANLVEQGMKSRLRKAMKRTQDYFFRTQHEDGYWWGELESNPTMEAEYIMLTHFMGSDEG
DRIPRVAEDIRRRQSEDGSWRMYYGAPGDLSTSIECYFALKLAGDPTDAPHMARARAFIL
AQGGVPRARVFTKIWLALFGQWDWKGTPAMPPDMMLLPKWAPFNIYRFASWARATIVPMT
IILTLHPTRPPRESAWVMELYPEGPVTFTLSRWRAKPFSLKGGFLLLDKALRVYCNLPFV
PRRERALKAAVDWIVSHQEADGSWGGIQPPWVYSLIALSALGYRLDHPVVAKGLEGFRQH
WSLPSEDDRALRVQACLSPVWDTCLAMRGLLDSGVPPDHPAVRRAAAWLIREEIRVKGDW
AVYRPHLEPSGWAFEFDNVHYPDIDDSAIIVTDLALARMNDDAGERARTASVDRAVAWLT
GMQGSGGGWAAFDWNNESRELAEIPFA
>A0A3Q9EZ54|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces cyaneochromogenes|TrEMBL
MTATTDGSTGALPPRAAAASDTDTETPVAAGVHEAAERAVRRATDFLLAKQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDEKTTQAAALFIRGEQREDGTWGTFYGAPGELSATVEAY
VALRLAGDAPDAPHMAKASAWIRAQGGIAASRVFTRIWLALFGWWKWEDLPELPPELIYF
PKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLEELHTDPAHPNPPKPLAPAVSW
EGAFQRLDKALHQLRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLEHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALVDAGVPADHPQL
VRAADWMLGEEIVRPGDWAVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ERVERAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIQWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALVAAGFPGSHP
AIRRAVTWLESVQNDDGGWGEDLRSYRYVKEWSGKGASTASQTAWALMALLAAGERDSKA
VERGIEWLAATQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFADR
SGATLAEVKGS
>A0A3S0KEL4|squalene-hopene cyclase|EC 5.4.99.17|Bacillus yapensis|TrEMBL
MNRRITDGIESLIEQLKKDQSFDGSWNYPFETGISTDCYMIILLRTLEIDDENLIKELVR
RIISKQEKNGAWKLFYDEGDGNVTATLEAYYALLYSGYFEKSGKRLTSARRFILKNGGME
KVHMFTKIMLAITGQYKWPSFFPIPLEFILLPNTFPINFYQLSVYGRANLLPIMILSDSE
FQMKTKKSPDLSDLYVRQNDEELFHEEEWRSLYGTIKSGIESLLEIPSQLKERAKTKGKQ
YMLARIEKDGTFFSYYSSTFLMIFALIALGYKTTHPVITRAVNGLKSMKTTIDGCTHMQY
TTANVWNTSLISYALQDAGVSGEESVIEKANHYLLRKQHTLYGDWVVHNPNSFPGGWGFS
NINSFNPDVDDTTATLRSIARDAIHNPSYRSSWERGMKWLLSMQNEDGGWPAFEKNTNSP
LFKLLPIEKGDFILTDPPTADLTGRTLQFLGDYTNLSSTHPSVRAGVESILTKQEKDGSW
YGRWGICYLYGTWGALTGLRAVGIQPEHPAIRKASSWLQSVQNEDGGWGESCKSDSQKKY
VALPASTLTHTAWAVDALISVSDKPSRAMKKGIEFLLENLEKKDWTTEYPKGQGMAGAFY
IHYHSYRYVFPLLALAHYDRKYEKS
>A0A532CP57|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp|TrEMBL
MNLIRTLLDRLSDSLFVSVSEKLELATEPSNAPPLRLVSDKPVLSPLIDATTRRPAGHSI
GQADTLDDAVRRSQAWFLSKQHVSEGYWVAELEADTTLTSEYLMLRRFLDRVDPERERKA
VYYLRAVQLPDGGWPIFYGGPSEISASVKAYFALKLSGVSADEAFMLRARDRILAMGGVV
SANVFTKITLALFEQYDWNGVPSMPPEIMLLPKRFYFSIYAISYWSRTVLIPLLVVFANQ
PVCRIPREQGIDELYLVPRSQIHYRDVPPFNKEQRWFTPHNFFVQLDRVLKLYDRMPLSW
LREKALQKAATWMLEHMKGSGGLGAIYPAMANSIVALRCLGYQVDDPLVRKAFQEIEALE
VYSTVSIGDQRVEALHLQPCHSPIWDTALLMNALVEAGMPQDHPSLQKASAYLVSRQTKA
VGDWKFSSPNAEPGGWYFQFENEFYPDVDDSAVVLMALAKVRMTPTIDLQESIQRGMNWV
LAMQGSDGGWGAYDKDNNRIVFNYIPFADHHALLDPSTADLTGRCLEMLAALGYDQTHPA
VAPALRFLKREQEADGSWYGRWGVNYIYGTWSVLAGLRAIGMDLSDPSIHRAVAWLESKQ
NPDGGWGESCLSYGDPAWSGKGDSTPSQTAWAIMGLMSAGMADGFSVARGVQYLLRHQMK
DGSWEEVRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRTRGKMRADEVRQQVFTSGC
HRADH
>A0A524IT23|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirales bacterium|TrEMBL
MRLLKQFIVRVTGNFFGTVIPKLRKQPVKKLQPSLKLVSHNPHPVVSPDTASQRGVSLGH
MEALESALQKGEQWLLSKQDLERGFWVEELEADTTLTSEYVMLRRFLGLVDSARERKAAC
YLLHTQLEEGGWPIFSGGPSDISATVKVYFALKLAGVASDEPVMQRAKALILEKGGVTQA
NVFTKITLALFGQYDWRGIPCMPPEIFLAPQWFYFNLYAVSYWSRVTIISLLIIFAHRPL
CPISKEQGIEELFVKPLNTVDFSQVPPLHRDSTFLSWRNFFVWVDSLLRLYESYPIKSLR
KKALKEAERWLIDHMDGEGGLGAIYPAMVNSLIALRAMGYAIDHPIIQKALGEIEELVIY
SNSANTTTPSMLHLQPCHSPVWDTALTMNALIESGVDLNHPALKKADVWLRSRQSLKVGD
WIVSSPEAKPGGWSFQYENDWYPDVDDTAAVVTAMAKIHQAETPDFDEVLQRGFHWALAM
QGSDGGWGAYDKDNNKLIFNKIPFADHQALLDPSTADLTGRCLEMLGTLGYDQSHQAVGP
ALDFLRTEQEPNGSWYGRWGVNYIYGTWCVLSGLRAIGVDMTAPWIQKAITWLESVQNSD
GGWGESCESYADVESAGKGESAASQTAWALMALLQAGETDSLSVVRGVNWLIRHQREDGV
WDEPFHTGTGFPRVFYLRYHGYFKYFPIWALGMYRNVKMTGEAKADQLRKKAQASRRQRG
WG
>A0A532AXJ6|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp|TrEMBL
MNLIRAFLDRLSDSLFVSVPEKLRLATELSKAPPLRLVSDKPMPSTPIDPAMRRPPSHSV
SPVDALDDAVRRSQAWFLSKQDASEGYWVAELEADTTLTSEYIMLRRFLDRVDPERERKA
VRYLRAMQLPDGGWPIFYGGPSEISASVKAYFALKLSGISADEPYMLRARDCIHAKGGVV
CANVFTKITLALFEQYDWEGLPSMPPEIMLLPKRFYFSIYAISYWSRAVLIPLLVVFANQ
PVCRIPKEQGIDELYVFPRAEIRYRDVPPFNKDQRWFTPHNFFVQLDGVLKLYDRMPLSW
LREKALHRAATWMLDHIKGSGGLGAIYPAMANSIVALRCLGYQVDDPLVRKAFQEIESLE
VYSIVSIGDQRVEALHLQPCHSPIWDTALLMNAFIETGMPQDHPSLQKAAAYLASRQTKT
VGDWKFSAPNAEPGGWYFQFENELYPDVDDSAVVLMALSKVRMAQTSELQESIQRGTNWV
LAMQGSDGGWGAYDKDNNRIVFNYIPFADHHALLDPSTSDLTGRCLEMLAALGYDQTHPA
VGPALRFLKREQEADGSWYGRWGVNYIYGTWSVLAGLRAIGVDLSEPYIQRAVTWLESKQ
NPDGGWGESCHSYAEDPAWSGKGDSTPSQTAWAIMGLMSAGMTDAFSVARGIQYLLRHQL
KDGSWEEVRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRTRGHMRADEVREQVLASG
CHRADR
>B1K290|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cenocepacia (strain MC0-3)|TrEMBL
MNDLTEMATLSAGAVPAGVDTAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKALEKLLVVHDDEAYCQPCLSPVWDTSLVAHALLETGDARAEEAVLRGLEWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLKQSDTYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRAAQWL
LSIQNKDGGWGEDGDSYKLNYRGYEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLV
AQQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A444QRT8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces albidoflavus|TrEMBL
SHPAPARTTATTTDSAVLDAAAVEAAAERARARAADHLLGLQSPEGWWKGDLDTNVTMDA
EDLLLRQFLGIRDEATTRSAALFIRGEQREDGTWATFHGGPPDLSTTVEAYVALRLAGDS
PDDPHMTRAAHWVRSQGGIAEARVFTRIWLALFGWWPWERLPELPPELIFLPPWAPLNIY
DFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPANPAPRARFAPLASWNGAFQRLDR
ALHAYRKIAPRALRKAAMATAGRWIVERQENDGCWGGIQPPAVYSMIALHLLGYDLGHPV
MRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALADAGVPADHPQLVRAADWMLD
EQIERPGDWSVRRPHLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDTARMERAISL
GVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDPPSADVTAHVVEMLAAEGLA
ADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALVDAGLPAAHPAIRRAVAWL
ESVQNDDGGWGEDLRSYREQGRMARGASTASQTGWALMALLAAGERESRAARRGVTFLAE
TQHEDGSWDEPYYTGTGFPWDFSINYHLYRQVFPLTALGRYTRGAAPEGA
>A0A7Y8HXH7|squalene-hopene cyclase|EC 5.4.99.17|Bryobacteraceae bacterium|TrEMBL
MESAWFESSARRAARRTIAAAQSRQALAEACAASLVRAQGALLNLQKPQGYWCGDLLADT
TLESDYILLQLWLHPPTDSGWNPPTLTRIRKAARSILDRQLPGGGFNIYPGGPADPSASV
KAYTALKLAGIDPASEPMARLRKAILDLGGIQAANSYVKINLSLFGLYPRQHVPTIPPEL
VLLPGGVLYEMSSWTRAIVVPLSIVQARGGVRPVPPDFNLHDIEAPGVSFRLPRRDRLSL
IFHGIDRGLKIWHYRGNQKLKNAAIRAAEKWMLDHTRYSNGLGAIYPSMMYLIMALDSLG
YPKDHPDYIEAVQQFDALMSESEDTLFFQPCFSPVWDTAYAMFALGETGQVEEEPMRRAA
DWLIAREVRRKGDWSVKRPDLEPSGWAFEFDNEHYPDIDDTAMVLLALMHARASDPEAQA
RCERRAMNWLIGMQSKDGGWAAFDVDNDWQLLNKVPFADHNAMLDPTCPDITGRVLESLI
RRGHGMSHPAIARGVDYLLRNQEPNGSWYGRWGVDYIYGAFLAIRALKHARAPVAREPVA
KAAHWLSQIQNADGGWGESCESYADNRFVAAPSTPSQTAWALIGLLAADPGAHPDAVRRG
LDYLLQTQNADGTWDEDLATGTGFPNVFYLRYTLYRNYFPIIALNMARRELGAEPGSALL
DAAAAASPRSA
>B2JPR7|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815)|TrEMBL
MNDLSMTQTLGEVLPQTLIDDHAPVAAALATGAAPVDALDAAVTRATEAILAVQKDDGHW
VYELEADATIPAEYVLLVHFLGETPNLELEQKIARYLRRIQLPNGGWPLFTDGAMDVSAS
VKAYFALKMIGDPEDAAHMVRARECILANGGAEAANVFTRILLALFGVVTWYAVPMMPVE
IMLLPKWFPFHLSKVSYWARTVIVPLLVLNAKRPVARNPRGVRIDELFRGAPVTTGLLPR
SGHQSKSWFAFFRAVDGVLRVTDGLFPKASRERAIKAAVSFVDERLNGVDGLGAIFPAMA
NSVMMYDVLGYPADHPNRAIARESIEKLLVVHEDEAYCQPCLSPVWDTSLAAHALLETGD
ARAEEAAERGLAWLRPLQILDVRGDWISRRPDVRPGGWAFQYNNAHYPDVDDTAVVAMAM
HRSAAVTNSNVDANAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPP
TADVSGRCLSMLAQLGEMPATSEPARRAYDYLLKEQEDDGSWYGRWGMNYIYGTWTALCA
LNAAGISLEDARIKRAAQWLVSIQNADGGWGEDGTSYKLDYRGYEKAPSIPSQTAWALLG
LMAAGYVDHPAVARGIDYLQREQRDHGLWDEERFSATGFPRVFYLRYHGYRKYFPLWALA
RYRNLKRTGEKRVTVGM
>A0A6I5I112|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4913|TrEMBL
MTATTDGSTGAVDPRAASASRPTTESTIAADAVLAAARRAAERSVEHLLGRQDEQGWWKG
DLATNVTMDAEDLLLRQFLGIQDPDTVRAAGHYIRGEQLGDGTWATFHGGPGDLSATIEA
YVALRLAGDRPEDPHMLRAAGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMF
FPKWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPEHPNPPKRPAPAAS
WDGIFQRLDKALHVYHRFAPRRLRRVAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVAPDHPA
LVKAADWMLGEEIDRPGDWAVRRPRLEPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPE
QARVDAAIARGVRWNVGMQSRNGAWGAFDADNTSAFPNRLPFCDFGEVIDPPSADVTGHV
VEMLAIEGHAGHPVTRRGIDWLLAEQDAGGGWFGRWGVNYVYGTGSVVPALIAAGLPATH
PAIRRAVDWLESVQNDDGGWGEDLRSYVEEKWIGQGASTASQTAWALLALLSAGRRDTVA
VTRGIAWLTETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFADR
TATREEA
>A0A850I0L7|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. 2S1|TrEMBL
MLSRDHSVAVDPVALEKSISKATEALLGYRQSDGHWVFELEADSTIPAEYVLLRHYLAEP
VDAGLEAKIANYLRRTQGAHGGWPLVHDGPFDMSASVKSYFALKMIGDSIDAPHMVRARE
AIRSRGGASGSNVFTRFLLALFGVVTWRATPVLPIEIMLLPMWSPFHINKISYWARTTMV
PLMVLAALKPRAKNPKGVGIDELFLEDPKSVRMAPKAPHQSAGWFYLFRSLDAVLRAIEP
MFPKRLRQRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYEALGEDENFPPRAITRRG
IDKLLVIGDDEAYCQPCVSPVWDTALACHALQEAGGEDTLAKAKQGLDWLKPRQVLELKG
DWAVKAPDVRPGGWAFQYNNDHYPDLDDTAVVVMAMDRVRRHSGTREYDEAIARGREWIE
GLQSRDGGWAAFDANNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLGQLGETAGSSKA
MADGIAYLRRTQLPEGSWYGRWGLNYVYGTWSVLSALNVAGIDRNDPMIRNAVDWLASVQ
NQDGGWGEDAVSYRLDYKGYEAAPSTSSQTAWALLGLMAAGEVENPAVARGVEYLKATQT
EKGLWDEQRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNSRVVGVGM
>A0A5C7V3J0|squalene-hopene cyclase|EC 5.4.99.17|Nitrosomonas sp|TrEMBL
RVQCRNALRGLLIDEGERAWCQPCTSPVWDTVLTSLALQEDPAIDQEPVQNALNWLVEKQ
VLDEPGDWRDKCPDLPGGGWAFQYANPHYPDLDDTAAVAWALDQGGMEQHRNALERAANW
LAGMQSTNGGFAAFDIDNVYHYLNEIPFADHGALIDPPTSDVTARCVRFLAKYGRHQHEV
WRGISFLLREQEKNGSWFGRWGTNYIYGTWSVLEAFRLAKFDMQHNSVRRAVQWLESVQR
ADGGWGETNDSYLDDNLAGQFAETSTAFQTAWAVLGLMAAGEVNSKSVRRGINYILRNQA
SDHLWEEPWFTAPGFPRVFYLRYHGYSKFFPIWALARYRAMTKTVAACI
>T2JBH3|squalene-hopene cyclase|EC 5.4.99.17|Crocosphaera watsonii WH 0401|TrEMBL
MQTQDRLTQKQPLSLKDAITASQNYLLSLQYPQGYWWAELESNITLTAETVLLHKIWGTD
KTRPLHKVEAYLRQQQREHGGWELFYGDGGEISTSVEAYMALRLLGVPQDDPALIRAKDF
IISKGGISKTRIFTKFHLALIGCYDWKGIPSIPPWIMLFPDSFPFTIYEMASWARESTVP
LIIVFNDKPVFSVDPVFNLDELYAEGLENVKYELPKNNNWGDIFLGIDQVFKFAEQVDLV
PFRKEGLKAAEKWILNHQQETGDWGGIMPPMLNSLLAFRTLNYDVNDPSVKLGFEAIDRF
SIEEDDTYRLQACVSPIWDTAWCVRALTDSGLEKDHFSLVKAGKWLLDKQVMEYGDWAVK
NKAGKPGGWAFEFTNRFYPDLDDSATVVMALNGIKLPDEARKQAAINRCLQWIETMQCKE
GGWAAFDLNNDQAWLNEVPYGDLKAMIDPNTADVTARVVEMLGSCDLEIESDRLNKSLNY
LYKEQEKDGSWFGRWGVNYIYGTSGVLSALAVINPEKHKTQMEQGINWLLSCQNKDGGWG
ETCRSYNDPSLKGKGVSTPSQTAWSLIGLLDAGEALNKFETDAIERGVNYLLDTQTEEGT
WEESEFTGTGFPCHFYIRYHFYRHYFPLIALGRYQNLSSEFGVRS
>A0A661NRB5|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MSTLGQPIGRAPAAGKLEGKLDGELDSELDGPDERFIADMLPRVSRTFALSISMLPPRLR
DPIGLGYLLCRIVDCIEDEADLDQSARERLFDLFDAAMGAQNGQDGDYGALEERSADVGL
GANAAEETLMTGAGAVFRAFRALPRAQREAIRPHVLEMSRGMREYTERADARGTFSIDDI
EDLERYCYFVAGTVGELLTDLFLLEVPSLGEAERRIVHDNAVSFGLGLQLVNIVKDVAED
ADRGICFLPTDRAAALGVDLSRLTAEDVRPAGLALVMEICDVAEAHLTSAQAYTLAWPGA
EGEAVRLFCAVPLSLALATLDEVQNGGDALRRGLTPKITRKLVGSITKDAIAGAKSDDAL
RALFDRLGSTPGVTDANTNITAETTRRETGAVAIDRATGWLREAQDEAGFWKGELETNVT
MDAEDLFLRQFLGIRTDEETQLAANWIRSQQRDDGTWANARGGPADLSTTVEAYVALKLA
GDDPEAPHMARASAWIVARGGLAETRVFTRIWLALFGLWPWDELPEMPPELMLMPSWMPL
NVYDFACWARQTVVALTIVMTYRPVRSLGIAIDEIDPKPRPTRKPSASLKGRMFEGLDRA
LSVYAKKPIAALRERGLREGERWIVQRQEADGSWGGIQPPWVYSMMALTLRGYPLDHPII
KVGLEGLDRFTIRENGARRLEACQSPVWDTAYAVQALADAGVPGNDEAMLRGADWLLGEE
VRQPGDWTIRRPNLEPGGWAFEFANVNYPDVDDTTEVIIALRRAVHPDPKRVESAIARGV
RWTIGMQSKGGGWGAFDADNTQALCRDIPFCDFGEVIDEPTADVTAHAVELLCREGLVAH
PATKAGVRWLLDNQEDDGSWFGRWGVNYVYGTGGVLMALAETDLEPTEPAIRRAVRWLHD
KQNADGGWGEDIRSYDDRSWAGRGTSTPSQTAWALLGLLAVGDDSENLRRGIDFLISTQN
TDGSWDEDEFTGTGFPGDFYINYHLYRQVFPTMALGRWARSIGIIQDAPKRGSKADPALV
QLRT
>A0A534ZTY0|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MVGGSTTGEGLGERVDHTIARASQYLFSTQHARGYWHAPLEANVTMEAEYVFFNRLLGRT
RPDVERRLAERLLALQQADGSWPIYHRGPGSLSTTIEAYFALKLVETDAREPALARARDF
ILGQGGLARAGVFTRMWLAYFNQFPWAGVPSMPVELVLLPPWFPVNIYAMSSWARGTVVP
LTLLTAHRPSVRIPAEAAVPELWVRPPTRDDVAFARSPELVTTRNFFLAVDRALKTLGPV
RWRPIRRRAVARAIEWILRHQDSNGQWGGIQPAMVNAVLALHAVGFAADHPVMMSGIQGV
EDFLVECEGTLMYQPCVSPNWDTALAARALLDAGLDPSHPALGRAGDWLVANQIFRPGDW
SVLNPTLEPGGWAFEFANDWYPDVDDSAVILTVLDALPIAQTAAGKRAIAAGLNWTLGMQ
SRDGGWAAFDTNNTAAFLNRIPFADMEAMIDPPTEDVTGRLLHLMGTVGYRPDFGRARRA
VEFLRRTQRSDGSWWGRWGVNFVYGTWCALAGLEAIGEDLRAPWIRRAVDWLATHQNADG
GWGETVASYDDESLAGQGDSTPSQTAWAVLGLLAADGPSSRAVERGIAWLCRTQGPDGTW
DERHFTGTGFPRHFYLRYHLYRHYFPLMALGQYRARLAARGAS
>A0A6G2K3G9|squalene-hopene cyclase|EC 5.4.99.17|Acidimicrobiia bacterium|TrEMBL
MTTARGMPAALPWLASAAGTGDLEAEAADALARSVDALAGLQDPAGWWKGDLETNVAIES
EDLLLRAFLGIDDAEVTALTANWIRSKQSPDGGWSNRYGGPSDLSLAVEAYAALRLAGDS
PDAEHMRLAAEFVRDMGGVECARVFTRIWLALIGQWSWRDLPAIPPELILLPRWLPLNIY
DFACWARQTIVPLSIVSTYRPQVDLGVTLDELRTGAVPPERVPRSMRTPAGCFQRLDRVL
HKFHALAPWRLRETSMKLAEQWIIRRQESDGCWGGIQPPWIYSIIALHLRGYPLDHPILA
KALACFDSYEVRQGDMRWMECCQSPVWDTALAVVALGDAGLRRDDPAMTAAADWLLDEEV
RVRGDWAARRPHLAPGGWAFEFHNDNYPDLDDTAEVVLALGHAQAGDSERANAAIARAVA
WAEGMQCSDGGYAAFDADNVRRLCEQLPFCDFGEVIDPPSADVTAHVVEMLCWVRAHTDI
PVDARRLRRAVDWLWLDQESDGSWFGRWGVNHLYGLGAVLPALRAAGVPTSDRRIRRAVR
WLHASQGPEGGWGEDLRSYESDYWRGRGDPTASQTAWALLALMAADEFGEPTRRGVAWLA
RTCRSDGTWDEPQYTGTGFQGYFYINYHLYRQVFPTMALGRFLRATAGEAPSR
>A0A7K2DLR8|squalene-hopene cyclase|EC 5.4.99.17|Acidimicrobiia bacterium|TrEMBL
MGVEQCLARARDRLLSLQDIEGWWKDELETNVSIEAEDLFLREFLGIADPEVTRQTANWI
RHSQRADGTWATFFQGPADLSVTVEAYWALRYAGDPVDADHMTKAADYIRSEGGLERSRV
FTRIWMALFGLWRWEDLPALPPEVILLPKQVPLNIYDFACWARQTVVSLTVVGAHRPVRS
MGINLDEIRTGATPPEQELAPPGTVARRFQRLDQALHHYENRPHRRLREWSLRRAEQWII
ARQEADGCWGGIQPPWVYSLLALYVRGYSLHHPILAQGLAGFDAWTIVEDDMRRLECCQS
PVWDTCLALIALADAGVDPDDSQMEAGARWLMDQEVQVVGDWAEQRPHLAPGGWAFEFEN
NFYPDLDDTAEVALALRRINHTDARKVNRALDRAVEWVQGMQCQDGGWAAFDADNCSPLV
AELPFCDFGEVIDPPSADVTAHVIEMLCELDGDGLGLKVDPVVVDRGVQWLSDEQEDDGS
WYGRWGANYIYGTGAAIPALISAGIPTDDDRVVRACKWLESVQNNDGGWGEDMRSYTNQE
WRGRGESTPSQTAWALLALVAAGRAGEETTRRGVAWLVENQRRDGDWDEPWYTGTGFSGD
FYIRYHLYRLVFPVMALGRWMRAMADEA
>A0A661K1S5|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MKTEIAYIHKIDAKHKVAQKSGKEESLSERIISSINRTTNYYLQCQHPEGYWWFELESNV
TITAEYLMLLKFLGIENPEREQKIVTHLLRKQRSDGTWAIYYDGPGEISATVEAYFALKL
AGYPEDSEEMTSARDFILKSGGVENCRIFTKIFLALFGNYSWERIPPFPVELILFPDWFP
FSIYAFSSWTRASLVPISILLHLRPVKTIEGARVDELYVSSPNGRKKPSNCMNFLIFSRH
IGKLLFKAPFRPLRNKALKKAEEWIVDHQEESGDWAGIQPAMVNSLLALSSLGYPLDHPV
IQKGLEALETFLIDKGGEVVLQSCISPVWDTALNCLALVEAGIPPKYPAIQLAAEWLLKQ
QIFRGGDWQVKRPDLEPGGWAFEFHNDHYPDVDDSAVVLMALQRAVGDNPTAKCAIER
>A0A534XDM9|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MSASEGQLTLVGRDAEGLPARAAQAISRATQYLLVTQHARGYWHAPLEANVTMEAEYIFF
NRLLGRTKPDLDRRMAERLVALQQAEGSWPIYAGGPGNLSTTIEAYFALRLAGHAPSEPA
LVRARDFILAEGGLARAGVFTRIWLAYFGQFPWIGVPAMPVELVLLPPWFPINIYAMSSW
ARGTVVPLTLLMAHRPYAHVGAEAAVPELWLRPPTPADLAFARSREFATVRNLFLAVDRA
LSVVGRSPWKPLRRRAVARAIEWILRHQDKNGQWGGIQPAMLNSVLALHAVGFAPDHPAM
VSGVHGVDDFLVECEGTLMYQPCVSPNWDTALAARALLDSGMEPTHPALERAGEWLVANQ
IFRPGDWAVQRPSLEPGGWAFEFANDWYPDVDDSAVILTVLRELPLAATPDGKRAIAYGL
NWTIGMQSRNGGYGAFDADNTAAFLNRIPFADMEAMIDPPTADLTGRLLQLMGGEGYGLD
FGRARRAVEFLRRTQRPDGSWWGRWGVNFIYGTWCALTGLAAIGEDLRAPYIRRAVEWLI
ARQNADGGWGETVASYDDETLAGRGESTPSQTAWALIGILAADGPASAAVERGIDYLVRT
QGADGTWTERPFTGTGFPRHFYLRYHLYRHYFPLMALGHYRAGLAGRSGEEG
>A0A8I1TXB3|squalene-hopene cyclase|EC 5.4.99.17|Nitrosospira sp|TrEMBL
MKSFESTARIYKEDRYLNPASLEAGLNAAREGLLRLQKEDGHWCFPLEADCTIPAEYVLM
MHFMDEVDTGLQARLARFVRGKQDSRHDGWSLYYGGDFDLSCTVKAYYALKLVGDSPEAP
HMARARAAILAHGGAARANVFTRIMLAMFGQIPWRGVPFVPVEIIFLPRWFPFHLSKIAY
WSRTVTIPLSILCSLKKRAANPRDIHIQELFTVPPNEERNYFPIRTRLNRFFLVLERTTS
VFEPYIPPFFRRMAIRRAESWMIERLNGDSGLGGIFPAIVNAYEALAALGYPYEHPYRKQ
CRDALQGLLVEQGESTWCQPCVSPVWDTVLASLALQEGGMDEKPVRKALDWLIPNQILDA
PADWQEDHPGLAGGGWAFQYANPHYPDLDDTAAVAWALHLADPKAYSESIARAADWLAGM
QSANGGFAAFDSDNTYYYLNEIPFADHGALLDPPTSDVTARCTGFLALYGQARHKEVVER
GLTYLFREQEPSGAWFGRWGSNYIYGTWAVLEAFRLARVDTGHLAIRRAVQWLKSIQQED
GGWGESNDSYFDPQQAGRFHTSTLSQTAWALLGLMAAGEGQSKEVYRGIEYLLRKQASDG
LWYDPWFNAPGFPRVFYLKYHGYTSYFPLWALARFRGGAAKNLA
>L7ZZ94|squalene-hopene cyclase|EC 5.4.99.17|Geobacillus sp. GHH01|TrEMBL
MDDERRVLIDALKQSQAADGSWRFPFETGISTDAYMIILLRTLGIHDEPLIQALVERIES
RQDPNGAWKLFADEGDGNVTATTEAYYALLYSGYRKKNDPHMQKAKARILEMGGLERVHL
FTKVMLALTGQHPWPRRFPLPLEFFLLPPSFPLNMYDLSVYGRANMIPLLVAAERRYSRR
TAKSPDLSDLVVSRNDWRLPESRSLWSYIKRSLIGLPDQLHHAAEQRAVRYMLDHIEPDG
TLYSYFSSTFLLIFALLALGYPKDDPYIQRAIRGLRSLRTEIDGHTHMQYTTASVWNTAL
ASYALQEAGVPLTDRTIEKANRYLLSRQHIRYGDWAVHNPYGIPGGWGFSDVNTMNPDVD
DTTAALRAIRRAAAKETAFRHAWDRANQWLFSMQNDDGGFAAFEKNVGKRFWRYLPIEGA
EFLLMDPSTADLTGRTLEYFGTFARLTKDHPAVARAVDWLLDHQEADGSWYGRWGICYVY
GTWAAVTGLSAVGVPIDHPAMQKAVHWLLSIQNADGGWGESCKSDGAKRYVPLGASTPVH
TAWALDALIAAAERPTAEMKAGVRSLIRLLRHPDWTASYPAGQGMAGAFYIHYHSYRYIF
PLLALAHYEQKFGPFVD
>T2AZ28|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PMWDTGLAMHAVLEANSEPDKTIMEKAANWLVERRILDVIGDWGANAHGVRPGGWAFQYW
NDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQH
ITFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGRWG
>T2AXM9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGSWG
>T2AZ96|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWYGRWG
>T2AYW4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLAMHAVLEANSVPDKIFMEKAANWLVKRQILDVIGDWGANVHGVRPGGWAFQY
WNDYYPDADDTAVVVMALHRADPDCYSEAIARGAEWIIGMQSGNGGWGAFDVNNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGLDNQAVARAIGYLKRGQEVNGSWYGRWG
>T2AYF8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSAPDKTIMEKAANRLVERQILDVIGDWAANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGSDNQAVARAIGYLKRGQEVNGSWYGRWG
>T2AY56|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGLAVHAMLEAGEPKNGARLNKAMRWMADRQVCDVSGDWATHRPGLRPGGWAFQY
ANDHYPDVDDSAVVAMALDRASDPKVKQGLPRAVEWIVGMQSKNGGWGSFDAENSHYHLN
HIPFADHGALLDPPTEDVTARCVGMLAQIGDEAGNDAIERGLSYLRETQQPDGSWFGRWG
>T2AZF6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAAHAVLETHGGNTHLLNKSCDWLSKLQIKEHTGDWGWRRKGLRPGGWAFQYN
NKFYPDVDDTAVVGMALHRQDPEKYADTISRAEEWIIGMQSSNGGWAAFDADNEYYILEN
LPFADHRALLDPPTADVTARCISFLTQIGTSNNHPISRGLEFLKRNQEEDGSWYGRWG
>T2AY28|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAICSNALLDSGLPTDHPALVRAGKWIVSKQVTKRGDWQVKNPEAEPGGWAFEFY
NELYPDTDDTAEILLFLNRVEILDNRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGKWGFNKQHPQVKRAIKFVKERQEVDGCWYGS
WG
>T2AYK6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAIIEICLHAGGVSADSAPLRKTTDWLLDREIQFRGDWKFKNPTDIEPSGWAFEY
ENKWNPDVDDTAMVLMALRRVPGSNRLRRDAAIDRGLKWMLSFQCKDGGWGAFDKDCTKD
ILNKVPFADHNAMLDPECADITARILEFLGQEGYGPDDRQVKKAIQFLRDNQEEDGSWYG
>T2AYL2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAIVLRGLAEIASPAVDSSNSLANAVDWLLAREVRFAGDWSRRVQAVPSGWCFEY
ANCYYPDVDDTAMVLIAFASWLKRHKACPDSQEKASEDSQGERIRHTRNAMRRGIQWLTA
MQNSDGGWGAFDRDNNHELLCKVPFADHNAMIDPSSPDLTGRVLEAYGSLGHGVGEPGVD
RAIEYLRETQEPDGSWFGRWG
>T2AZ82|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAIVLRGLAEIASPAVDSSNSLANAVDWLLAREVRFAGDWSRRVQAVPSGWCFEY
ANCYYPDVDDTAMALIAFSSWLKRHKACRGSQEKASEDSQGERIRHIRNAMRRGIQWLTA
MQNSDGGWGAFDRDNNHELLCKVPFADHNAMIDPSSPDLTGRVLEAYGSLGHGVGEPGVD
RAIEYLRETQEPDGSWFGRWG
>T2AZH1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIEVEKNIQSAEIENALNWLKKQQLSDEPGDWRIQKPELAGGGWAFQY
SNYYYPDLDDTSMVAWAMHRVNNKEYIESIQRAANWVAGMQSRNGGFGSFDIDNTHFYLN
EIPFADHGALLDPPTADVTGRAIALLSLADREKYTKNIKEGINYIKSEQEDDGSWFGSWG
>T2B019|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTCIAQLALLESGIDPEDPMVQSSARWLMDKQIYAAADWQVRAKGTRPGGWSFEFD
NLIYPDIDDASIVVMALDQVRLPEAEEPRRADSIQRGVEWMAGMQSKNGGWAAFNKDNNK
KYLTKIPFSDFGEALDPPSVDVTAHLLEMYGRLGYTKEDRAVGRGFAYVISEQEEDGSWY
GRWG
>T2AZ70|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTCIAQLALLESGIDPEDPMVQSSARWLMDKQIYATADWQVRAKGTRPGGWSFEFD
NLIYPDVDDASIVVMALDQVRLPEAEEPRRADSIQRGVEWMAGMQSKNGGWAAFDKDNNK
KYLTKIPFSDFGETLDPPSVDVTAHLLEMYGRLGYTKEDRAVDRGFAYVISEQEEDGSWF
GRWG
>T2AZ53|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLNDEPGDWRIQKPELSGGGWAFQ
YSNYYHPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAVTLLSLADKKIYAKNIKDGVDYIKSEQEEDGSW
>T2B045|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLATHAMLEANLSSGPRILENDSTSKACKWLEKLQIKDCAGDWAVWRPNLRPGG
WAFQYHNDYYPDIDDTAVVAMALHRTGNKIYEPALLRAAEWIIGMQSKNGGWAAFDADNE
YHLLENMPFADHGALLDPPSVDVSARCISFLTQLGYDQTNGTIKRGIEYLKKNQEEDGSW
FGRWG
>T2AYN9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTSLNGLSLLESGLTLNDNAIQKACKWLGKKQILKIKGDWIVNNKNLLPGGWASQY
KNDFYPDVDDTAVVAMFLDRAGYQNKKILEKACNWIVGMQSENGGWGAFDKNNTFYYLNN
IPFADHGALLDPPTADVSARCVSMLSQIDKKNYKNVIQKGVSFLKNKQEKDGSWYGSWG
>T2B096|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSLALIETEYKQHNSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAITLLSLADKKIYAKNIKDGVDYIKSEQEENGSWYGSW
G
>T2AXM3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPGLSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTKNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGSW
G
>A0A7W3M5S7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces calvus|TrEMBL
MTATTDGSTGAALPPRVTAASENDTDIPEAAGVPDIAARAVRRATDFLLSRQDDQGWWKG
DLETNVTMDAEDLLLRQFLGIRDEDTTRAAALFIRGEQREDGTWATFHGGPGELSTTIEA
YVALRLAGDPPDAPHMAKASAWVREQGGIAASRVFTRIWLALFGWWRWEDLPELPPELIW
FPSWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPRHPNPPRPLAPPLS
WDGAFQRLDRTLHALRRAVPRRLRAAAMHTAARWIIERQENDGCWGGIQPPAVYSIIALH
LLGYDLNHPVMRAGLESLDRFAVWREDGARMVEACQSPVWDTCLATIALADAGLPADHPQ
LVKAADWMLGEQIVRPGDWSVRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHHD
PERLDNAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGLAHDPRTRRAVQWLLAEQEPDGSWFGRWGVNYLYGTGSVVPALTAAGLPGSH
PAIRRAVAWLESVQNDDGGWGEDLRSYRHAREWAGRGTSTASQTAWALMALLAAGERESR
AVERGVEWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFAA
RPAAASARAEPTAAGVDLPLAEAKGS
>A0A6H9T6L8|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia latens|TrEMBL
MNDLTEMATLSAGTVPAGLDTAVARATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSPGWFAFFRAVDHVLR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKSVEKLLVVHDDEAYCQPCLSPVWDTSLAAHALLETGDARAEEAVLRGLEWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLKQTDTYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCALNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGYEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLI
AQQNDEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A6B0ZS04|squalene-hopene cyclase|EC 5.4.99.17|Acidimicrobiia bacterium|TrEMBL
MGVEQCLARARDRLLSLQDIEGWWKDELETNVSIEAEDLFLREFLGIADPEVTRQTANWI
RHSQRADGTWATFFQGPADLSVTVEAYWALRYAGDPVDADHMTKAADYIRSEGGLERSRV
FTRIWMALFGLWRWEDLPALPPEVILLPKQVPLNIYDFACWARQTVVSLTVVGAHRPVRS
MGINLDEIRTGATPPEQELAPPGTVARRFQRLDQALHHYENRPHRRLREWSLRRAEQWII
ARQEADGCWGGIQPPWVYSLLALYVRGYSLHHPILAQGLAGFDAWTIVEDDMRRLECCQS
PVWDTCLALIALADAGVGPDDSQMEAGARWLMDQEVQVVGDWAEQRPHLAPGGWAFEFEN
NFYPDLDDTAEVALALRRINHTDARKVNRALDRAVEWVQGMQCQDGGWAAFDADNCSPLV
AELPFCDFGEVIDPPSADVTAHVIEMLCELDGDGLGLKVDPVVVDRGVQWLSDEQEDDGS
WYGRWGANYIYGTGAAIPALISAGIPTDDDRVVRACKWLESVQNNDGGWGEDMRSYTNQE
WRGRGESTPSQTAWALLALVAAGRAGEETTRRGVAWLVENQRRDGDWDEPWYTGTGFSGD
FYIRYHLYRLVFPVMALGRWMRAMADEA
>T2AXZ3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIFMEKAANWLVKRQILDVIGDWGANVHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDCYSEAIARGAEWIIGMQSGNGGWGAFDVNNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGLDNQAVARAIGYLKRGQEVNGSWYGRWG
>T2AY51|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGRWG
>R9VY63|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAQAVFTRGGTRVPSDDPRMQKAADWLLSKEVRHKGDWAMKVPNTEPGGWYFEFN
NEFYPDVDDTAQVLLALNKVDNPRERYQDQVARRAIDWEFAMQCRNGGWGSFDKDNTKMI
FQYVPFADHNAMLDPPTVDITGRMLEMLAAYGYTRDDKRVQKAIKFILDEQEPDGSWFGR
WGVNYIYGTFLVLRGLDAIGVCHNEPQMQQAAEWIRMVQNSDGGWGE
>R9VY55|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAITAHALLDMGHPKARAAVSRGLDWLVPLQILDVRGDWISRRPNVRPGGWAFQF
ANPHYPDVDDTAVVAMAMERADRENGTALYGEAISRGREWVVGMQSSDGGWGAFEPENTQ
YYLNNIPFSDHGALLDPPTVDVSGRCLSMLAQLGETLLNSEPARLALDYIVSDQERDGSW
YGRWGLNYIYGTWTALSALNAAGLPPTDSRMKRAAHWLISIQNADGGWG
>A0A7W8B4J6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces spectabilis|TrEMBL
MTPYVSFPPSLLHNSVLALGAAVRHALDAQLADGSWPSDPEPRIFETAMAAYTLYRAADG
RTSPQIDGARAWLQKASAQTQHPVAHAIEEWLRALALTPESVAMAPVRECQDAGCSGRAI
YIHAVGLAAGAPGTDAALLRQQARDELAKAGRARLRDSQLAILRSAEIIAASQLDADEPT
EALDNLAAAQSPDGGYNMQPATTALVLLALTVSGKGPQIAARCRTNLLREQRSDGTWRLV
CNDVWDVGEMLFALRGAPGFEIGAERKALDFLAQAQNPDGGWSYKAGIQSDNVSTAHALL
ALPATPHGREVWPRAEAFLRGTQRNDGLWASWLSAEEPTEPDLIAMMISAVQGHGSTAID
LGPARAWLASADFQARETFRWYSPTGFFTRPAIAALGADSPPARAFLRPLIDEQKPDGGW
PDHPRCEHSGAAGTGLAISTLAPAAHHILPNALHKGVDYLIKSQRADGSWSGSPIASGPR
PLLAELTTETHAFAATALRDVVLAFSSRKEPASTDQPAGGR
>A0A429X625|squalene-hopene cyclase|EC 5.4.99.17|Siminovitchia terrae|TrEMBL
MTDSTRELINKITEILKDEQTDNGSWDYPFDTGVKTDAYMIILLRTLEINDEDLIRKLTE
RILSKQEKNGSWKLYNDEKDGNLSYTLEAYYALLYSGFYSKHSSRIRMAKSFILKNGGME
KAEMFTKILLALTGQYKWPAFFPLPVELILLPLSFPINFYDFSVFGRANLAPIMILSAKK
YSRKTKGSPDLSDLFVKRTNEFFSEGEKRGFENIFSIIEHGIKSILMAPQQIHSYAIERA
KQYMFNHLESDGTFYSYFSATFLMIFALMSLGYKKDDPVILKAVDGLKAMECTIDGYPHM
QYTTANVWNTTLISFTLQNAGLPPSDPTIIAANEYLLERKHYKYGDWVINNPGVLPGGWG
FSDINTFNPDVDDTTAALRAFSPLVTENSAILSSWDRGTNWAISMQNDDGGWPAFERNVD
KKIMNLLPIDRVRFLVSDASSADLTGRTLEFLGNYTNMPKKSKKIRDGVKWLTADQKKDG
SWYGRWGICYIYGTWAAVTGLMATGIDRQHKSIQKATSWLKKIQNKDGGWGESCNSDLEN
KYVPLQKSHITQTAWALDALIASENLPTPEIEAGVRYLLQSYDHKDWTWYYPVGQGMGGS
FYIHYHSYQYIFPLLAIANYEKKFHR
>A0A3M2D0R6|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
MKRLKALIVRLSDSLLNNIALGLPRSGVRSRRKAPPLKLVSHNPHPVVESSQVLGRAEPT
VAGHAEAIEDALHRGAAWFLAHQDSENGYWVHELEADTTLTSEYIMLRRFLNQVDLDRER
KAVRYLLHTQLPEGGWSIYAGGPADVSASVKAYFALKLAGVSADEPAMQLAREAILRQGG
VVSANVFTKIMLALFGQYDWRGIPSMPPELVLAPRWLYFNLYAVSYWSRAVIIPLLIIFA
YRPLCPIAREQGVEELFVVPPERVDYRTSPPFQRDAAWFSWRNFFVWVDGLLKLYECYPL
VELRRRALKRAEQWMLEHMQGEGGLGAIYPAMANSVMALQVLGYSPDHPVRAKALSEIEA
LEVHTAAPDGNPSPPMMHVQPCFSPVWDTALTINMLIERGLPLDHPALLRAASWLRARQC
ARIGDWIVSAPQAKPGGWYFQFENEWYPDVDDTAAVVIALAKLHAMPPAEQDDAIRRGYE
WVLALQSSDGGWGAYDKDNNRLIFNKIPFADHQALLDPSTADLTGRCLEMLGTLGYDRTH
PAVQPALEFLRREQEPNGSWYGRWGVNYIYGTWCVLSGLRAIGMDMSAPWIQRAVTWLES
VQNQDGGWGESCLSYEDPAWAGRGESTPSQTAWAVMGLLAAGVSDSINVLRGVHYLLKHQ
REDGVWDEPLHTGTGFPRVFYLRYHGYSKYFPLWALAMYRNVKMQGQSRADELRKAAQAV
RRRSFS
>A0A371QB63|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces inhibens|TrEMBL
MTATTDGSTGALPPRAPSASDATAEKTEATHSTRTAVRQDTADAARRATARATDYLLSVQ
DPAGWWKGDLETNVTMDAEDLLLRQFLGIQDPELTEAAARYIRGEQRTDGTWATFYGGPG
ELSTTIEAYVALRLAGDAPDAPHMATASAWIREQGGVAAARVFTRIWLALFGWWKWDDLP
ELPPELIYFPKWFPLGIYAFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPRDPNPP
RPLAPATSWDGVFQRLDKALHVYHKVALRKLRGAAMRSATRWIIERQENDGCWGGIQPPA
VYSIIALHLLGYDLDHPVLRTGLASLDRFAVWREDGPPGAARGSAPTRMIEACQSPVWDT
CLATIALADAGLPADHPQLVKAVDWMLAEQIDRPGDWSVKRPQLPSGGWAFEFENDNYPD
IDDTAEVVLALRRVKHPDPQRVDAAVSRAVRWNFGMQSKNGAWGAFDVDNTSPFPNRLPF
CDFGEVIDPPSADVTAHVVEMLADVGRTHDPRTRRGIAWLLAEQEPSGAWFGRWGTNYVY
GTGSVLPALAAAGIPGSHPAVRRAVGWLERVQNEDGGWGEDQRSYRDKEKWAGRGASTAS
QTAWALMALLAAGERDGAAVRRGVRWLIDTQREDGSWDEPYFTGTGFPWDFSINYHLYRQ
VFPLTALGRYVNGGPACAPVGS
>A0A5B9EFX0|squalene-hopene cyclase|EC 5.4.99.17|Terriglobus albidus|TrEMBL
MAIDASKSTASSQAGTQPRFGRMDLELDKVSSGIKRAVDWLFGQQHQDGYWCGELEADVM
LEADYIFVHTLLGTGDRAKMQRAVNEILRHQNADGGWSLYPGGPSNVNYGVKAYLALKLM
GWKADHPLMVKARESVLSLGGVVECNTFTKLYLCALGAYDYDAVPAIPPEIILFPNWFYF
NIYEISSWSRGILVPLSIIYAKKPFKKLAPEEEIDELFVGGRDRANLHLRWDKKRPVSWR
NFFLLCDRVAHWAERVHIRPLRSMAIKKAEKWMLERFEKSDGLGAIYPAMLNAIVALRCL
GYSMDDPVLIRAVDEFEKLGIDCPEGTQDYPTPTFRMQPCFPPVWDTAQAIYALGEAGVA
KDDPRMIQAADWILSKEVRHKGDWAEKVRNVEPGGWYFEFNNEFYPDVDDTGQVLLALKC
VENPRERYQYEVCERALNWIWAMQCKNGGWAAFDKDNTKTIFEQIPFADHNAMLDPPTVD
ITGRMLEMLALYGYNRSDKRVEKAVQFILSEQESDGSWFGRWGVNYLYGTFLVLRGLQSM
GMWSHEPCVLQATEWVRMVQNPDGGWGESCGTYDDPLQRGLGSSTPSQTAWALLALLAGG
DVRSDSVAKGVRWLIDHQHEDGSWDELVPGRNGESYYTGTGFPRVFYLGYHLYKQYFPLL
ALTTYIKARETEVSGALE
>S6FL59|squalene-hopene cyclase|EC 5.4.99.17|Bacillus velezensis UCMB5033|TrEMBL
MSTIHENVRSRQKKTISLLRETQNADGSWSFCFEGPILTNAFLILLLTSLGDNDKELIAE
LAEGIRAKQRPDGTFANYPDDRKGNVTATVQGYAGLLASGLYSRSEAHMIQAERFIISNG
GLRNVHFMTKWMLAANGLYPWPALHLPLSFLVIPPSFPLHFYQFSTYARIHFVPMAVTLN
KRFSLKNPNVPSLAHLDRHMTKNPFTWLRSDQDENRDLSSLFAHWKRLLQIPAAFHQLGL
RTAKTYMLDRIEEDGTLYSYASATIFMVYGLLALGVSRHSPVIRKALAGTKALLTSCGDI
PYLENSTSTVWDTALLNYALMKSGISDNDQMITSAARFLRERQQTKVADWAVHNPHAEPG
GWGFSNINTNNPDCDDTAAVLKAIPRKLYPASWERGLSWLLSMQNSDGGFSAFEKNVNHP
LVRLLPLESAEEAAIDPSTSDLTGRVLHCLGEAGLSSDHPQIEKAVQWLIRHQEEDGSWY
GRWGVCYIYGTWAALTGMKACGVSQNHPAVKKAIRWLKSIQNEDGSWGESCKSAEEKTYV
PLSYGTLVQTAWAAEALLQYEKTHHQAVTKGISFLIENRHYEGAAFSYPTGIGLPKQFYI
RYHSYPYVFSLLALSTFMKMSEKEEEK
>A0A0H2XZW0|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cenocepacia (strain AU 1054)|TrEMBL
MNDLTEMATLSAGAVPAGVDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKALEKLLVVHDDEAYCQPCLSPVWDTSLVAHALLETGDARAEEAVLRGLEWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLKQSDTYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRAAQWL
LSIQNKDGGWGEDGDSYKLNYRGYEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLV
AQQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A291T0B1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces malaysiensis|TrEMBL
MSVAREATARAVEHLLSRQDERGWWKGDLETNVTMDAEDLMLRQFLGIQDPDTLDAAARY
LRSQQAPDGTWATFHGGPPELSTTIEAYVALRLAGDEPDAPHMTAASAWVRSRGGVAASR
VFTRIWLALFGWWRWEDLPELPPEIIYFPKWFPLNIYDFGCWARQTIVPLTVVSAKRPVR
PAPFPLDELHTDPRKPNPPLPQAPIATWDGVFQRLDRALHAYHKVALRPLRRSALRSCAR
WIVERQENDGCWGGIQPPAVYSVIALHLLGYDLDHPVMRAGLESLDRFAVWREDGSRMIE
ACQSPVWDTCLAAIALADAGLAPDHPALVKAADWMMAEQIDRPGDWSVRRPGLPSGGWAF
EFHNDNYPDIDDTAEVILALRRVDHPEPARIEAAVRRAMRWTLGMQSKNGAWGAFDVDNT
SPLPNKLPFCDFGEVVDPPSADVTAHVVEMLAHEGRTYDARTRRGISWLLSEQEPSGAWF
GRWGTNYVYGTGSVVPALISAGVPASHPAVRRAVRWLESVQNEDGGWGEDQRSYLDAEWM
GRGASTASQTAWALLALLAAGEGGGAAVERGVTWLAETQREDGSWDEPYFTGTGFPWDFS
INYHLYRQVFPVTALGRFVHGEPTGARPRSS
>A0A538MR39|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MTIAPDRTRTALDTAVERATERLLELQHPDGWWVGELESNATMIAQHLFWHHFLGLRTPE
LDRKIGNELLARQRDDGTWAIWFEGPPDLSTTIEAYTALKLAGFDPGARARDYIRSEGGV
SRARVFTKSFLALLGHWPWQWVARLPPEVILLPPDGPFSVYNFSCWARQTVVPLSVVQAL
RPVRAARIDLREIGARAGQAKPPPRPGPIRRVAFATAERWVRDRQEADGSWGGIQPPWVW
SIIMLAALGYGFEDETLRAAVEGWQGFTIDEGDRLRPEACQSPVWDTALAAIALLEAGLS
PTHPALRRAGEWLVEEEVAARGDWAIRRPDLPPGGWAFEFENDLYPDVDDTAVVALALRR
LGLGADAVERGLAWTAGMQSRSGGWGAFDVDNEAHWLYKLPFCDFGKVTDEPSADVSAHA
LEALAPESRYAEEVERGLAWLLAEQEREGSWFGRWGVNHVYGTGAALPALEACGVPSGHP
AMQRAVEWLRSVQQPDGSFGEDIRSYADAGWRGRGHPTPSQTAWALLGYVAAGEADSDSA
RRAADWLCSEQLSNGDWQEDHYTGTGFPLDFMIRYHLYRLHFPLMALGRLRERLAA
>A0A538J524|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MTIVQELTGIDTAVDRGAERLLSLQHPDGWWKGELESNATMIAQHLVLLHFLGLRDAETD
RLLANELLARRRADGTWSIWFEGPADLSVTVEAYAALKLAGVDAGDATRQYIRRSGGVAR
TRIFTRAFLALIGQWPWRRLAHVPVELILLPANGPLSVYDFACWARQTMVALSVVEALQP
VRPSAIDLSEIGGRKTAGHGMPRLSGCRRRAVAVAEHWVRERQEADGSWGGIQPPWVWSL
IMLAALGHGFEDETFARGLAGWQRFMVRDGDRLRPEACQSPIWDTALAVLALRAAGVPAD
DPRLQAAGSWLLGEEVTVRGDWAIRRPGLAPGGWSFEFDNDLYPDVDDTAVVALALRELD
LGDDAVRRGLDWMVGLQSRSGGWGAFDADNEALWLYRLPICDFGKVTDEPSADVTAHALE
AFGHEDGYGSSLASGLDWLLAEQETDGSWFGRWGVNHLYGTGAAVPALEACGLPADHPAI
RRALAWLDSVQQPSGAFGEDILSYRDAAARGRGAATPSQTAWALLAYISGGAAKGLSTRR
TAEYLCQSQRPDGDWDEQHYTGTGFPLDFMIRYHLYRLTFPLLALGRLRERLNG
>A0A538J299|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MTILDRRTALDTAIDRGTARLFELQHPDGHWKAELESNVTMTAQHLFWNHFAGLRTPDLD
RRIANEILARQRDDGTWAIWWEGPADLSTTIEAYVALKLAGVDPGPKALAFIQREGGLRR
ARVFTKCWLALLGQWPWQRIPSIPPEIVLLPPSGPFSIYDFACWARQTIVALSVVMALRP
VRPARIDLREIGARPGTTRPARRPGPLRAQAIAAAERWVRERQEADGGWGGIQPPWVWAI
VMLAALGHGFEDDTFRRAVEGWHSFMVEDGERLRPEACQSPLWDTALALLALGACGLTTD
DPRVAKAVDWLLAEEIDVPGDWVVRRPHLKPGGWAFEYANDLYPDIDDTAVIAVALRKLG
AGDDAVRRGLDWVVGMQSRNDGWGAFDADSNAMWLYKIPFCDFGKVTDEPSADVTAHVLE
ALGPEGIYGDAAAAGVEWLLAEQEEDGSWFGRWGVNHVYGTGAALPGLEACAVPPEHPAM
RRAVAWLDSVQQEHGGFGEDIRSYGDPSWRGRGFATPSQTAWALLGYISAGAAESAGAQR
AAEFLSRAQLDNGDWREDHFTGTGFPLDFMIRYHLYRLNFPLLALGRLRERLNG
>A0A7W2HIK7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces himalayensis subsp. aureolus|TrEMBL
MTATTDGSTGAVPPRAASASGTTGTTRTTESTPAAAGTHDAATRALQRATDFLLARQDAQ
GWWKGDLETNVTMDAEDLLLRQFLGIRDESTTKAAALFIRSEQRDDGTWATFYGGPGELS
TTIEAYVALRVAGDSPDDPHMAKAAAWIREQGGIAASRVFTRIWLALFGWWKWDDLPELP
PELIYFPKWFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLEELHTDPGNPSPPRSL
APAASWDGVFQRLDKALHAYHKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYS
LIALHLLGYDLEHPVMRAGLESLDRYAIWRGDGARMIEACQSPVWDTCLATIALADAGLP
ADHPQLVKAADWMLGEQIVRPGDWSVRRPHLTPGGWAFEFHNDNYPDIDDTAEVVLALRR
VKHPDPDRVEKAIDRGVHWNVGMQSRNGAWGAFDVDNTSSFPNRLPFCDFGEVIDPPSAD
VTAHVVEMLAVDGKAHHPATRRGIEWLLAEQEANGSWFGRWGVNYVYGTGSVVPALTAAG
LPASHPAIRRAVAWLESVQNDDGGWGEDLRSYRDIEGWSGRGASTASQTAWALLALLAAG
EQESKAVERGIAWLAETQADDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHG
EPFSGKVS
>A0A4U6S9W9|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium elkanii|TrEMBL
MLARDHSVAVDPVALEKSISKATEALLGYRQSDGHWVFELEADSTIPAEYILLRHYLAEP
TDAGLEAKLGNYLRRVQGAHGGWPLVHDGPFDMSASVKSYFALKMIGDSVDAPHMVRARE
AIRSRGGASGSNVFTRFLLALFGVVTWRATPVLPIEIMLLPMWSPFHINKISYWARTTMV
PLMVLAALKPRAKNPKGVGIDELFLEDPKSVRMAPKAPHQSASWFYLFRSLDAVLRVIEP
MFPKRLRQRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYEALGKDENFPPRAITRRG
IDKLLVIGEHEAYCQPCVSPVWDTALTCHALQEAGGDDTLAKAKQGLDWLKPRQVLELKG
DWAVKAPDVRPGGWAFQYNNDHYPDLDDTAVVVMAMDRVRRHTGTREYDEAIARGREWIE
GLQSRDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLGQLGETAESNKA
MADGVAYLRRTQLAEGSWYGRWGLNYIYGTWSVLSALNVAGVDRNDPMIRKAVDWLVSVQ
NQDGGWGEDAVSYRLDYKGYEVAPSTSSQTAWALLGLMAAGEVENPAVARGVEYLKATQT
EKGLWDEQRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNSRVVGVGM
>I3XGM0|squalene-hopene cyclase|EC 5.4.99.17|Sinorhizobium fredii (strain USDA 257)|TrEMBL
MNKHSGNRTAIDPAALEMSIASATEALLAYRHADGHWVFELEADSTIPSEYILLRHYLAE
PIDVVLEAKIGNYLRRTQGAHGGWPLVHDGPFDMSASVKSYFALKMIGDSVDAAHMVKAR
EAIRARGGAANSNVLTRFLLALYGVVSWRAVPVLPIEIVLLPIWSPFHLYKISYWARTTI
VPLMVLAVLKPRAKNPKGVGIEELFLQDTKSVGMNPKAPHQSWGWFLLFRGIDGILRVIE
PHLPKKLRERAIASALAFTEERLNGEDGMGAIYPSMANIVMMYDALGKDDHFPPRAIARR
AIDKLLVIGEEEAYCQPCLSPVWDTALTCHALQEVGGANALAKAKQGLDWLKPRQVLDVK
GDWAVKAPNIRPGGWPFQYNNAHYPDLDDTAVVVMAMDRAQRHAGSKEYATAIARGREWI
EGMQSRDGGWAAFDVNNLEYYLNNLPFADHGALLDPPTEDVTARCVSMLAQVGEFTQSSK
AVAEGIAYLRRTQHAEGSWYGRWGLNYIYGTWSVLCALNAAGIDHQDPMIRKAVEWLVSI
QSWDGGWGEDAISYRLDYSGYEQAPSTSSQTAWALLGLMAAGEVEHPAVARGVNYLKNAQ
TENGLWDEQRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNV
>A0A8J7M3P4|squalene-hopene cyclase|EC 5.4.99.17|Thermohalobaculum xanthum|TrEMBL
MNNTVFSADSLRGAEVLDAPTRETRKAIIAERADRLWDMQKPDGHIVFELEADCTIPAEY
VLLRHFLGEIDREREARIARYLRKVQNPDGSWPLFHDGAGNISATVKGYWALKLTGEDID
APHMARARSWLLGQGGAAKANVFTRIMMALFRQIPWRGMPCIPVEAILMPEWFPFHMSKI
AYWSRTVLTPLLILYAKRAKAANPTGLDIRELFVVPPEEQRKWQINPTGSRIGEMFLLLD
KALQRAEPHVPRGIRERAIRKAEEFTISHLNGDSGLGAIYPAMANAVMALRVLGYPDDHP
HMKIAREAIEKLVIEREDQIYLQPCVSPVWDTSLAAHAFLESGERDDPRLIAALDWLASK
QILDHVGDWAVRRPGLRPGGWAFQYDNPDYPDVDDTAVVVAAMHRADPKRYAMNIDRACE
WLVGMQSRSGGWGAFEPENEHFYLNSIPFADHGALLDPPTVDVTARCVGCLAQVDRVKYA
EAVRKGVGFIRREQEADGSWFGRWGANYIYGTWSALVALKGAGEDMNQPYVRRAVAWLKA
RQRPDGGWGEGLESYEDWGAGFARSSTASQTAWALLGLMSAGEVESGAVTRGIDWLAAAP
RDEDGPRWEEAHWTGTGFPKVFYLKYHGYAAFFPLWAMGRYENLMTSNDREVHWGL
>A0LLW2|squalene-hopene cyclase|EC 5.4.99.17|Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)|TrEMBL
MNPIRGKRGSAADFLEEEYQWENLADHGESGRTPGGGHPAALKEYEAGSATEHTGHHCVH
HLGVRNSWLRKIEKAIDNACGQLFKTQYEDGYWWSELESNVTITSEYIMLLYLLEVSRPE
QQKSMVKYLLNQQRPDGSWGLYYGDGGNLSTTIEAYFALKLAGEHCESEPMRRAREFILS
KGGIESARVFTKIWLALFSQYDWDKVPSMPVELVLLPSSLYFNIYEFSSWARGTVVPLSI
VMSIRPRCPLPAKCSIKELYVPGSKHKNFASCTHKLFFLFDRIAKAFERRPVPSLRNKAV
QAAETWVLDHQEDSGDWGGIQPPMVYSVLALYYLGYPLDHEVIVKGIKALDAFCMEDEEG
TRMQSCVSPVWDTALTVLSMLDAGVAAEHPGLEKAGRWLLENQVLTGGDWQIKNDSLPGG
WAFEFYNTRYPDVDDSAVVLSTLNRFNAERVEGLEFAKCRGMEWCLSMQSSNGGWAAFDK
DNTLEILNRIPFADQEAMVDYPTADVTGRVLEAMGYLGYDGSHPRARKAIQFLKKRQERD
GCWWGRWGVNYIYGTWSVLKGLISIGEDPRAAYIRAAVRWVKDHQNSDGGWGETCESYEN
PELRGQGPSTPSQTAWALMSLIACGEMKSQEASRGIQYLLRTQKRDGTWEELHFTGTGFP
KHFYIRYHNYRNCFPLMALGQYLRALER
>A0A849S0Q2|squalene-hopene cyclase|EC 5.4.99.17|Methylococcaceae bacterium|TrEMBL
MFTDAQTQTPSGTVASSATAIYAKPYNLDKAISRAQDKLLSLQNPDGYWVFELEADCTIP
SEYILMMHYLGEIDLALQAKIAVYLRSRQAEDGSYPLFTGGPGDISCSVKVYYALKLAGD
SPDDGHMVRLRAYILSKGGAAKANVFTRIALATFEQLPWRGVPYIPVEIMLLPKWFPFHL
DKVSYWSRTVMVPLFILCTLKATAKNPSKTQILELFVTHPDQEQHYFPERTLLNKIFLGL
DFLGRATRPLIPKKAHEHALELAKNWIIERLNGEDGLGGICPAMMGAYEALLLLGMPKDH
ELIVTARKAIDKLLVINEHDAYCQPCLSPVWDTALAALALQEADKGKASDQKIANPALTR
AYDWLKSKQLSDEPGDWRISKPDLAGGGWAFQFENPYYPDVDDTAVVGFAMAESGLPHLD
ESIHRATRWIVGMQSKNGGYGAFDVDNTYYYLDEIPFADHGALLDPPTSDVSGRCAMLMA
KVAQDHDEYLPALERTINYIRSEQEADGSWFGRWGTNYIYGTWSILLALEQTALPKTDPL
YTKAVAWLKSVQREDGGWGEDNYSYHDKSVSGSYRFSTAFQTAWATLALMAAGEAHSPEV
KAGIDFILHHQQADGVWNDKCFTAPGFPKVFYLKYHGYDKFFPLWALARYRNELNTK
>A0A652K794|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. adm13(2018)|TrEMBL
MTATTDGSAGAVGPRATAASTTDELRPDGAAAPGSGGRAAPPDPTRLDEAAARATERAAE
HLLALQDAEGWWKGDLETNVTMDAEDLLLRQFLGILDAGTTRAAALHIRREQREDGAWAT
FYGGPGDLSATVEAYVALRLAGDPPEAPHMARASAWVRERGGVASARVFTRIWLALFGWW
RWEDLPELPPELLFLPSWFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDP
ARPAPPRPLAPATGWDGLFQRLDKALHVYHRVAPRALRRTAMNQAARWIIERQENDGCWG
GIQPPAVYSIIALHLLGYDLGHPVMRAGLDSLDRFAVWREDGSRMVEACQSTVWDTCLAT
IALADAGLAPDHPALVKAADWMLGEEITRTGDWAVRRPGLPPGGGWAFEFHNDNYPDIDD
TAEVLLAFRRVRHPDPARLEAAVARGTRWTLGMQSKGGAWGAFDADNTSALPNKLPFCDF
GEVIDPPSADVTAHVVEMLAFEGLADDPRTRRGVDWLLAAQEPNGAWFGRWGVNHVYGTG
SVLPALTAAGLPASHPAIRRAVHWLGSVQNEDGGWGEDLRSYDDEAWIGRGASTASQTAW
ALLALLAAGERDSAPVRRGVAWLAGTQREDGSWDEPYFTGTGFPWDFSINYHLYRLVFPL
TALGRYVHGEPSPGRAR
>A0A534ESJ9|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MSRKAGTSAALAGTEGLLRADAPARKLPGEKLSPLEYAIAAARDELIRLQRPDGSWQLEL
EADCTIPAEYIMMMHFLGELDAALEAKLAAYLRQRQAGYGGWPLYHGGAFDMSCSVKVYF
ALKLAGDDPESPHMARARAAILERGGAASCNVFTRIALALFGQLPWRGVPYIPVEIVLLP
CWFPFNIHRVSYWSRTVMVPLLILCTLKPRARNPRNVDIRELFTTPPSQERRYFRRPLGG
SAALARAFFCLDRLARSLDGFIPRALREHALERAEAWMLERLNGEEGLGAIFPAMVNALE
ALSVRGYSPDHPHRRGAKRALEKLLVEDYSSAYCQPCASTLWDTALASLAMQEEGSAGAR
AAALRGLEWLEPRQLLDDPGDWRTRRPHLPGGGWAFQRANSYYPDLDDTAAVAWSMHRSP
DPGRFSFALSRALDWLVGMQSENGGFASFDVDNTSYYLNEIPFADHGALLDPPTSDVTAR
VVTALARVGRPEDRGALTRAIDYLRREQEANGSWFGRWGTNYVYGTWSVLSAFAEARIGP
DDPAVERAVSWLESRQNPDGGWGESNDSYEPGRAGASAPSTPHQSAWAVLALIAAREAGS
DAVRRGIEYLLRTQRPDGLWSDPSFTAPGFPRVFYLRYHGYCAYFPLWALAAYRNSTAAG
PGTVH
>A0A7T4U0M9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces alfalfae|TrEMBL
MTATTDGSTGAVTPRAASASHSIDTPAATPPTAGTREAAALAIQRSTDFLLSRQDAEGWW
KGDLETNVTMDAEDLLLRQFLGIGDERTTRAAALFIRGEQREDGTWATFFGGPGELSTTI
EAYVALRLAGDLPDAPHMARAAEWIRDRGGIAESRVFTRIWLALFGWWSWDDLPELPPEL
IYFPPWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHVDARVPRPPKPLAPA
TSWDGLFERLDKALHVYHKVAPRRLRGAAMNSAARWIIERQENDGCWGGIQPPAVYSIIA
LHLLGYDLEHPVLKAGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADH
PQLVRAADWMLGEEIVRPGDWAVRKPRLAPGGWAFEFHNDNYPDIDDTAEVALALRRVAH
PDQARVDNAIARGMRWTLGMQSKNGAWAAFDADNTSHFPNRLPFCDFGEVIDPPSADVTG
HVVEMLAVEGRSHDPRTRRGIEWLLAEQEDNGAWFGRWGVNYLYGTGSVVPALITAGLPA
SHAAIRRAVRWVESVQNDDGGWGEDLRSYRDRGWVGHGTSTASQTAWALLALLSAGERDA
PSVERGIAWLAATQRPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPFP
AGSAHAGKGS
>A0A6P1AQR0|squalene-hopene cyclase|EC 5.4.99.17|bacterium LRH843|TrEMBL
MTHHTKNLRDKIVKQLKDSQTPDGYWDYPFETGIETDAYMIILLKSLEINDEDFIYELTK
RIISKQEENGAWKLYYDEDRGNLSATVEAYYALLYSGYYKKDDDPMRAAKAFILKNGGME
ASHMLTKTMLATTGQLPWTRFPIPVESILLPLSFPINFYDFAVFGRATLAPLMVIASKKY
YKKTKKSPDLSDLFVSAHRSYRWFECRDSERIVSEIEQGIKNLLGLPEYIHSLAIQRTKQ
YMLSHIEPDGTLYSYFSSTFLMIFALLSLGFSPKDPVILKAINGLKGMKCKINGQVHMQF
TTASIWNTSLISYVLQHTGISSTDPVIVKANQYLLQSHQYKYGDWAIHNSDALPGGWGFS
HSNTMNPDVDDTTASLRALSQSIGSNTSLLAHWDAGIRWVSSMQNDDGGWPAFEKNVDKT
IINLFPVEGGKFLLTDPSSADLTGRTLEFFGNFTNLPKQHPMMKHGVNWLLRHQEKNGSW
YGRWGICYLYGTWAALTGLASAGISSEHSAVKRAVQWLHHIQNKDGGWGESCQSDFRGMY
IPLGNSNITQTAWALDALIAFATKPTPEIDAGIDYLLSSYDQKDWTKQYPVGQALGGGFY
IDYHSYQFVFPLLALANYEKTFNN
>A0A7X2PLF1|squalene-hopene cyclase|EC 5.4.99.17|Bryobacterales bacterium|TrEMBL
MTPGPQIRDSLISAAGGTLGRATARLLELQSPNGEWCAELTADTTLESDFILLQLWLYPP
VSGRWNPESRILVEKAAKSILNRQLEDGGFNIYVDGPTEISATVKAYFALKLSGYDVNGE
RMTKARECILARGGIQAANSYVKVNLSLFGLYPREACPSIPPEFVLLPFNFLFQMSSWTR
AIVVALSIVHASNPMRPVPESFNLDELFLPGVPLGLKRSPKLFTWRNFFLAADRFLKFWE
KWGSRTIRAKAIREGERWMVERTKDSDGLGAIYPPMMYAIMAFDVLGYPPDHPERVEALR
QFNHLMVDEDDRFLFQPCFSPIWDTAMAAYAIGEAGTTSTEPLRRTADWLLAREIRRKGD
WSVKRPDTEPSGWCFEYANAFYPDIDDTAMVLLALNHAHASNPEAQSACHRRALDWLLAM
QSSDGGWAAFDVDNDWHILADVPFADHNAMLDPTCADITGRILEALKAHGFGREHPAVRR
GAEYLIRHQEADGSWYGRWGVAYIYGTCFALRGLAAAGESDREAHVLRGGEWLRSIQNAD
GGWGECCASYDNGCFTPAPSTPSQTAWAIMGLIAGGDTTSLSVRHGIEYLIETQRRDGDW
DERLATGTGFPRVFYLNYHLYRLYFPVMALSAFLKAGSAS
>A0A839W733|squalene-hopene cyclase|EC 5.4.99.17|Azospirillum sp. OGB3|TrEMBL
MQDHNASTTLRVQRAEPSAKAVSAAVAEATDALIRRQQADGHWVFELEADATIPSEYLLL
HHILDEIDPELEAGLAAFIRGRQGRDGGWPLFFGGAMDISCSVKAYFALKAAGDSPDAPH
MRRAREAILARGGAARCNVFTRILLAQFGQVPWRAVPAMPVEVMNLPPWSPFHISRISYW
SRTVVVPLLVVMAHRLRARNPRGIGIAELFTEPPERVRNWHSNNNRGGWATLFRALDAAL
HAVEPRLPANGRQTAIDRAVRFVTERLNGEDGLGAIFPAMVNAVLMFHCLGVPPDHPDAA
TARRALRGLVVRQPGRVYCQPCLSPVWDTAIICNALLETGSPQARAAARRGADWLIDRQI
LDVEGDWAWQRPGLASGGWAFQYNNAHYPDTDDTAMVVMALQRLDAERYGEPIRRARDWI
VGMQSRNGGWGAFDAENQHDFLNHIPFADHGALLDPPTSDVTARCVMMLARLGEGRDTLP
TRRGLTFLEREQESDGAWFGRWGTNYVYGTWSALEALNAAGVPHAAPAVQRAAQWLLAHQ
RADGGWGEDGASYWAGNPRGEGPVSTASQTAWALLGLMAAGKGNHPAVDRGVEYLLSARD
AEGLWSEQPFTAVGFPRVFYLKYHGYAASFPLWALARYRALRV
>A0A136K7H3|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp. OLB3|TrEMBL
MRLLKSFFNRLSDGLLVQVPSRIRAARDFASEPVLRLVGGKSNGSVAVDSSSKRAPSHPS
GQLEALEEALRKSQTWFLARQNATEGYWVAELEADTTLTSEYLMLRRFMNCVDPEREQKA
VRYFKSAQLPSGGWPIYHGGPADISASVKAYFALKLSGVSPNEPFMEAARKCILDMGGVT
AANVFTKIALALFGQYDWRGVPSMPPEIMLLPKRFYFSIYAISYWSRAVVIPLLIIFAKR
PLCRIPKEQGIDELYKEPLDQIDYSAFPPFKKDRTWFTAKNFFITLDGLLKIYDRSPVEW
LRQQALKRAESWMLDHMKGSGGLGAIYPAMANSVVALNCLGYANDDPLVVKAMQEIEELE
IHDRVQENGQSVDAMHLQPCHSPIWDTALLINALVEAGMPSDHPVLQKAGEWLLSKQTKT
VGDWIISSPGAEPGGWYFQFENELYPDVDDSAVVLMALAKVRLPDEARQYQAMCRGYRWV
VSMQGSDGGWGAYDVDNNRIVFNYIPFADHRALLDPSTADLAGRCLEMLATLGYDWTHPS
VASALAFLKKDQEADGSWYGRWGVNYIYGTWSVLSGLRAIGEDVSSPSIRRAVAWLESKQ
NPDGGWGESCLSYADLSQSGRGESTPSQTAWALLALMAGGVTDSFSLARGIHYLIRNQRK
DGSWEEVRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLKTRGTTRAEELRLQATTQDN
SGRRVDGVRPFPPTFLAIIPEEPT
>I4IP69|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa PCC 9701|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWSDVFLWLDGLFKWAEKTNLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVDDPIVARGLKAVDNFAIQ
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKGVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYSDLKAMIDPNTADVTARVLEMLGTCDVKMEEIRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A6P0WKJ7|squalene-hopene cyclase|EC 5.4.99.17|Caldora sp. SIO3E6|TrEMBL
YLFVTLDDTFKLVEDWDIVPFRQEGLEAAERWVLERQEVTGDWGGIIPAMLNSLLALRSL
DYDVADPVVARGLKAVDNFAIETAETYTIQPCISPVWDTAWVIRALVDSGIAPDHPALVQ
AGEWLLNKQILSYGDWAMKNRQGKPGGWAFEFENRFYPDLDDSAVVVMALDAVRLPQEDQ
KRAVMARGVAWMASMQCQEGGWAAFDINNDADWLNYLPYADLKAMIDPNTADVTARVLEM
LGSCNLSIDQSKLERSLTYLLEEQEDDGSWFGRWGVNYIYGTSGALSALSVITPQKHRLS
IQKGASWLVSCQNTDGGWGETCRSYDDPTLKGQGDSTASQTAWALIGLMAAGEATGSWAT
EAINRGINYLVTTQLPDGSWQEDYFTGTGFPSHFYLKYHFYQQYFPLIALGRFSRT
>A0A3N7ZT49|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp9143|TrEMBL
MIRRMNKPAPSSWSALDTAIARGRDALMRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDARQEKMARYLRAIQRLDTHGGWDLYVDGDPDVSCSVKAYFALKAAGDSEHAPHMVRA
RDAILKLGGAARANVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNIAIPELFVTPPDQERHYFPPARGMRRAFLALDRVVRHVEPL
LPKRLRQRAIRHAEAWCAARMNGEDGLGGIFPPIVYSYQMMDVLGYPDDHPLRRDCENAL
EKLLVTRPDGSVYCQPCLSPVWDTAWSTMALEQARGVAAPDAGEPAGSLNELDARITRAY
DWLAERQVNDLRGDWIENAPADTQPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRTHRNA
DGSHPYAARVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRADDRASLARAIDYVKRTQQPDGSWWGRWGTNYIYGTWSVLAGLALAGED
PSQPYIARALAWLRARQHANGGWGETNDSYIDPALAGTNAGESTSNFTAWALLAQMAFGD
CESDSVKRGIAYLQSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
RGAAPVGARAVPAATDAALA
>A0A849MEB0|squalene-hopene cyclase|EC 5.4.99.17|Proteobacteria bacterium|TrEMBL
MTLDTNNDNSPNQTQQESHPKKPAIDIDDAILAAKNKLLEQQHDDGHWVYELEADCTIPA
EYILMNHFVDEIDDETEQKIAQYLRDQQNEEGGWSLYTGGDFDISCSVKAYYALKIIGDD
PHEEHMVRARNMILNHGGAARSNVFTRILMALFEQVPWRATPFIPAEVIILPKWFPFHID
KVSYWSRTVMVPLFILCTMKPKAANPRGVDIRELFSIPPEDEQHYFKVTTPLTRAFLILD
HVGRVAEKIVPKFVRQYSIRKCEQWFLARMNEEYGIGGIFPAMVNVFESLVILGYKKNDP
IRIQARQAIEALLVKRGNTMYCQPCVSPVWDTCLASQAMIETETEENVTAEIEHALDWLK
DRQLSDEPGDWRIPRPNLAGGGWAFQYSNYYYPDLDDTSMVAWAMHRTGKEQYIEPIQRA
ANWVAGMRSTGGGFGSFEVNNTQYYLNAIPFADHGALLDPPTADVTGRVVALLSLADKEK
YVSVIKDAINFLKSDQEEDGSWFGRWGTNYIYGTWSVLTALELADEDPNQAYIKNAIAYL
QDMQNEDGGWGESNDSYYPPKHRRPFESTAYQTAWALLSLLAVGEAETDTVKRGINYLIS
NQTSDGHWYDDSYTAPGFPRVFYLKYHGYTKYFPLWALARYRNLLQNKV
>A0A6I1QM06|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
MTTVTPKLAALAAGPVEDGIERAVAWLRSRQQDGGYWWAPMDTNVCIEAEYLMLMRFLGH
EDPDQIAKMRRHILGTQRPDGSWATCFGGPPDLNCTVEAYFALKLTGSSPDNPPMRAARE
VVLSLGGVPATRVFTRLWLALFGQYPWSDLPAMPPEAVLLPGWSPINIYAFACWARQAVV
PILVVRTLEPVHTVPPDQAIPELYPAARRPQRSTGETGGILSARNLLSVVDRFLRFYEPR
GPKPLRALALRRCEQYIVTHQEADGSWGGIQPPWVYSLIALTLLGHDLESPVVRKGIDGL
QGYLVEEDGRLWMQACISPIWDTCLAMIGMLDCGVPPDDPAVGKAAAYLVDRQIRKPGDW
QAQVSGVEPGGWAFEFANDWFPDTDDSAEVLLALDRARLPDDAGRLDAIERGDRWLLAMQ
SANGGWGAFDKDNTRRLVTQIPFADFGETIDPPSEDVTAHVIEYLGQRGYDRNFPPVARA
ITYLQSTQTIDGSWFGRWGVNHVYGTGAVLVGIAQVGEEPILPYIQRAVGWLKSVQNDDG
GWGESCASYNDPSLKGVGPSTPSQTAWALLGLLAVGERESDAAARGVAYLVNNQRPDGTW
DEDQYTGTGFPGDFYLNYRLYRHYWPMMALGRYRHGA
>A0A6B2WJR2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID13588|TrEMBL
MTATTDGSPGAPAPQAPSASTTSAPHPVHVGGAEAAAERAAQRAAANLLAAQHPDGWWKG
DLETNVTMDSEDLLLRQFLGIQDERTTQAAARWIRSLQRDDGSWPTFHSGPGDLSATVEA
YVALRLAGDTPEAPHMANASAWVREAGGVVGARVFTRIWLALFGWWRWEDLPELPPEIIY
LPKWFPLNIYAFGCWARQTIVPLTVVAAHRPVRPAPFGISELHKDPAQPNPPRPPAPLAS
WDGLFQRLDRALHLYRKVGVRPLRRTALKACARWIIERQEDDGCWGGIQPPAVYSVIALH
LLGYELDHPVVRAGLDSLDRFAVWPDEDTRMIEACQSPVWDTCLATIALADAGVATDHPA
LVKAVDWMLDEQITKPGDWAVQRPGLQPGGWAFEFHNDNYPDIDDTAEVVLALLRVQHPD
PGRVDAAVEKAVRWNIGMQSKNGAWGAFDADNTSAFPNRLPFCDFGEVIDPPSADVTAHV
VEMLASLGLEDDTHTRRGIDWLLAEQEDSGAWFGRWGVNYIYGTGSAVPALVAAGLPVSH
PAVRRAVGWLESVQNQDGGWGEDLRSYSDQEWIGRGVSTASQTAWALLALLSAGERDSDA
VERGVRWLVDTQKADGSWDEPYFTGTGFPRDFSINYHLYRMVFPLTALGRYARSEPLGVI
GNVTKGKAAG
>A0A4Z1D6B8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces griseoluteus|TrEMBL
MTATTDGSTGATLPPRAAAASDTDSTDPLAAGVPEAAERAAARATEYLLARQDPEGWWKG
DLETNVTMDAEDLMLRQFLGILDAATTRAAALFIRGEQREDGAWATFYGGPGDLSATVEA
YVALRLAGDAPDAPHMARASAWVRERGGIASARVFTRIWLALFGWWKWEDLPELPPELIW
FPTWLPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPANPSPPKPFAPLTS
WDGAFERLDRVVHRLRKAVPRRVRRAAMNAAARWIVERQENDGCWGGIQPPAVYSVIALH
LMGYDLRHPVMRAGLESLDRFAVWREDGSRMIEACQSPVWDTCLAVIALADAGVPADHPR
LLKAADWMLAEEIRRPGDWSVKRPELPPGGWAFEFHNDNYPDIDDTAEVALALRRVSHPQ
PERVDGAIARAVRWNFGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMMAAEGLAHDPRTRRGIAWLLAEQEADGSWFGRWGVNYVYGTGSVVPALTAAGLPASH
PAIRRAVHWLQQAQNDDGGWGEDLRSYKYAREWSGRGASTASQTAWALMALLAAGERDSE
AVERGVRWLADTQRDDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFDK
APLAARRGVRAPAGGS
>A0A544ZJX2|squalene-hopene cyclase|EC 5.4.99.17|Microbispora sp. KK1-11|TrEMBL
MTGVTTGVTTGVTTGVATSAARAATALKAARDHLLGLQAPEGWWKGELQTNVTMDAEDLL
LREFLGVRTEEETAEAARWIRSQQRPDGTWANFHDGPADLSTTIEAYAALRLAGDPPSAP
HMRAAAAYVRGAGGIESARVFTRIWLALFGQWRWEDLPVIPPEIMFLPPWCPLNVYDWAC
WARQTIVPLTIVTAHRPVRPLPFGLPELRTGRPARRAPRTGWDAAFAALDRALHRYERRP
VAGLRRAALRRAAEWVVARQEADGSWGGIQPPWVYSLIALHLTGYGIGHPVMRAGLAGLD
RFTIREDGTRRLEACQSPVWDTALAMTALLDAGLPRDHAALARAGEWLLREEIRGPGDWM
VRRPGLAPGGWAFEFDNDGYPDVDDTAEVILALRRLGRPEARPALERGLRWMAGMASRDG
GFAAFDADNTRELCLRLPFCDFGAVIAPPSADVTAHVVEALAVEGMARSPAVRRAVVWLL
RAQEPDGSWFGRWGANHVYGTGAVLPALAAAGVRPGAPCVRRAVAWLEAHQHPCGGWGED
MRSYRDPAWIGRGEPTASQTAWALIGLLAAGERGPSVDRGVAWLADSQRPDGTWDEPHYT
GTGFPGDFFINYHLYRLVFPLSALGRYLRLHETAGPEATP
>J7QP20|squalene-hopene cyclase|EC 5.4.99.17|Methylocystis sp. (strain SC2)|TrEMBL
MNAAARIDANFTAVSGEALETSIQNAKRALLSLGKGEGHFCFELEADTSLSAEYVLMRHF
RGEPVDAELERKIAVYLRRCQGDHGGWPLYQDGPFHISSSVKAYFALKMIGDDVDAPHMA
RARAAILAYGGAARSNVFTRALLALYGEIPWRGVPVMPVEIMLLPKWFPFHLDKISYWGR
TVLVPMLVLMTKKPRAKNPRNIHIGELFTTPPDEVKVWPKGEHQTWPWANIFGRIDKLLR
LIEPHMPSGPRERSIELAMEWTTERLNGVDGLGGIFPSMVNSLLMYDVLGVPDADARKKQ
AREAIERLLVVTDTEVYCQPCVSPVWDTCLTAHTLLETGDEDAREQARQACEWLAPLQVL
DVKGDWAAQRPNVRPGGWAFQYANAYYPDVDDTAVVVTAMDRLTANDASRPYDERIARAK
EWIVGMQSKNGGWGAFDADNTCHYLNHIPFADHGALLDPPTADVSARCVSMLAQLGDTID
SSECLKRGVDYLLKEQEKDGSWFGRWGANYIYGTWSTLCALNAVGLPHAHDAYRRAVAWF
VAIQNGDGGWGEDLSSYKLDYKGYEKAPSTASQTAWALLALMAAGDVDHPAVARGIAYLQ
STQNDAGLWNEARFTATGFPRVFYLRYHGYGKFFPLWALARYRNLRRANSKRVQVGL
>A0A8F9HSF7|squalene-hopene cyclase|EC 5.4.99.17|Polymorphobacter sp. PAMC 29334|TrEMBL
MSVINHPAFASAVTTATGSAVTIAELDAAVGRAADALARLQQPDGHWVFELEADATIPAE
YILLRHFLGEPDDLDLEARIGRYLRRIQGDHDGWALFHGGAFDISATVKAYFALKMIGDA
VDAPHMARARAAILAHGGAAAVNVFTRIQLALFAAGPWQTVPTMPPELILAPRWFPVHLS
KMAYWARTVIVPLLVLAALRPVAKNPRGIKVDELYLPRATVKPKSNVAGAKAFWKAAFGA
LDVVLKAGDGLWPKRLRARAIDRCRSFVIERLNGNDGLGAIYPAMANSVMMFDALGDPEH
RDIARAAVEKLIVRREDGEIYCQPCFSPVWDTALAAHAMLEVRSPAAEAAADAGLDWLIP
RQVLDVKGDWAENAPDLRPGGWAFQYNNAHYPDLDDTAAVVCALDRARGRVGARYDEAIA
RGTEWTVGLQSKDGGWGAFDADNSYHYLNNIPFADHGALLDPPTADVSARCVSMLAQLGE
PVGSARMAAALAYLRKEQEADGSWFGRWGVNYIYGTWSALCALNAAGLTGADPAVRRGAD
WLIAVQNPDGGWGEGCDSYALDRTGHVPADSRASQTAWALLGLMAAGEAEYPAVARGVAW
LAANQSDDGVWPEEDYTGGGFPRVFYLRYHGYAKIFPLWALARYRNLRASNSVHVAHGL
>A0A4S3PQ06|squalene-hopene cyclase|EC 5.4.99.17|Bacillus timonensis|TrEMBL
MFNKVNDGIGQLIDSIRKDQSSNGAWTYPFETGISTDCYMIILLRSLEINDEKLIQQLVE
RILSRQEDNGAWKLFYDEGEGNISATVEAYYSLLYSGYIKKQDPKMKRAKSFIIKNGGLK
DIHMLTKLLLALTGQHRWPPYNPLPVELILLPHSCPIHFYRFSVFGRANLTPIMILADKK
YSLTTKMSPDLSDLSSKRNEDELDFRNSQEWRSFYSTIKQAINQLIGLPSHLHQLAIEKA
KHYMLQRIEPDGTFLGYFSTTFLMIFALLSLGHSKNHPIIINAVNGLKGMKTVIDGHVHM
QYTTADVWNTSLLGYALQEAGVPSNDSMIKKANHYLLQRQHLKYGDWAVQNPAGVPGGWG
FADMNTIQPDVDDTTASLRSMARMVKKVPVYRQSWDRGLQWLLTMQNDNGGWPAFEKNTD
SKLFSLLPIEKAEYILTDPSSADLTGRTLEYLGNYTNLLNNYSSVQSAIQWLYRNQEDDG
SWYGRWGICYIYGTWAAVTGLRAVGVLTTHSSIKRAVTWLETIQNSDGGWGESCNSDRNQ
KYVPLKTSTLTHTAWAVDALISANDKSNNSIKKGIDFLLINLNQADWTTTYPKGQGMAGD
FYIHYHSYRYIFPLLALAHYKKKYKQKS
>A0A437PGU6|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium oryzihabitans|TrEMBL
MGKVETLSRVGTQGIALEDVERRISQASRALGQLAGPDGHWCFELEADATIPSEYVLYHH
FRGSIPTPDLEAKIANYLRRTQSAQHGGWSLVHEGGFDMSCSVKAYFALKMIGDSPDAPH
MARARDAILSRGGAAHANVFARTLLALYGEVPWTAVPVMPVEVMLLPKWFPFHLDKVSYW
ARTVMVPLFVIQAKKPRAKNPRGVRIQELFTQAPERVRHWPAGPQESSPWRPVFAAIDRV
LQTVEGAFPAGSRARAIDKAVAFVSERLNGEDGLGAIFPAMVNAVIMYECLGYPEDHPLV
VTARSSVEKLVTVKEHEAYVQPCLSPVWDTALAAHAMMEVGGPDAEKRAKRALDWLKPLQ
VLDIKGDWAASKPDVRPGGWAFQYANPHYPDLDDTAVVVMAMDRLQSRRSPSEDAADYGT
AIARAREWVEGLQSRDGGWAAFDADNTYHYLNYIPFSDHGALLDPPTADVTARCISMLAQ
LGETRDTSPAMARGIEYLIADQEEDGSWYGRWGMNYIYGTWSALCALNAAGFDPEAAPVR
RAAAWLAAVQNPDGGWGEDAVSYKLEYRGYERAPSTASQTAWALLGLMAAGQAESPAVAR
GINYLTRTQSADGLWDEERYTATGFPRVFYLRYHGYAKFFPLWALARYRNLKRGNSLRVA
VGM
>A0A4U5WPA2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces lasalocidi|TrEMBL
MTATTDGSTGALPPRAASASDTTRITTPEAAGAPQAAERAMRRATDFLLSRQDAQGWWKG
DLETNVTMDAEDLLLRQFLGILDEATVGAAALFIRGEQREDGAWPTFYGGPGDLSATVEA
YVALRLAGDAPDAPHMARASAWVRERGGIAAARVFTRIWLALFGWWKWEDLPELPPELLY
FPKWFPLSIYNFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPADPNPPRPPAPLAS
WDGVFQRLDKVVRGYRSVAVRRLRRAALNSAARWIIERQENDGCWGGIQPPAVYSVIALY
LLGYDLEHPVMRAGLESLDRYAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQ
LVKAADWMLGEQVVRPGDWSVRRPELPPGGWAFEFHNDNYPDMDDTAEVVLALRRVRHHD
PERVENAIARGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGYAHDPRTRRGIEWLLAEQEPEGSWFGRWGVNYLYGTGSVVPALTAAGLPTDH
PAIRRAVTWLERVQNDDGGWGEDLRSYQDPGRWSGRGASTASQTGWALLALLAAGERGSR
AVERGVEWLARTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFAN
QAVKPRPAHQPATPAAEAGTG
>A0A6G8ZY36|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium symbiodeficiens|TrEMBL
MDSVNATSREAPQSGVLESSIASATQGVLGFQQPDGHWVFELEADCTIPAEYVLLRHYLA
EPVDTVLEAKIGNYLRRIQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDPVDAPHMVRA
REAIHARGGAIHSNVFTRFMLAMFGVVTWRAVPVLPIEIVLLPFWSPFHINKISYWARTT
MVPLMVIAALKPRAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFLLFRSLDAILRVV
EPMFPKSLRKRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKDENFPPRAITR
RGIDKLLVIKDDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLDWLIPKQELEV
KGDWAVKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGATGYDAAIARGREW
IEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETAQTS
KHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVRHDDPMIRKAASWLAS
IQNADGGWGEDAVSYRLDYKGWEAAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIAT
QDKKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A4R4XMI2|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. KC06|TrEMBL
MTTTDVSGLTGAAAAAAGAARDHLLGLQSPEGWWKGELETNVTMDAEDLLLRQFLGIRSE
SETAEAARWVRSRQREDGTWANFHGGPPDLSTTVEAYVALRLAGDPVDADHMRRAAKYAR
DAGGIEATRVFTRIWLALFGQWSWDDLPVMPPELMYLPKRVPLNVYDWACWARQTIVPLT
VLGSLRPVRALPFDLPELRSGVRPVKDEKGWGRFFNGLDRVLHVYEKRPVRPLRTAAMRR
AADWIIARQEADGCWGGIQPPWVYSLMALHELGYGLDHPVIRRGLDGLERFTIRDEKGRR
LEACQSPVWDTVLAMNALGDAGAPADDPALRRAAAWVVGEEVRGPGDWSVRRPGLAPGGW
AFEFDNDVYPDTDDTAEVILALRKVDFPEAEAPIGRAVRWLEGMASRDGGYGAFDADNTQ
DLCNKLPFCDFGAVIDPPSADVTAHVVEALCGEGLAESPTVKRAVVWLLKAQEADGSWFG
RWGANHVYGTGSVVPALVAAGVGRGKPAIRRAVAWLEQHQNDDGGWGEDLRSYDDPSWVG
RGESTASQTAWALLALLAAGERSPAVDAGVRWLVDNQRPDGTWDEDQYTGTGFPGDFYIN
YHLYRLVFPISALGRYLSKEVRPS
>A0A7L8VRC5|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. SEMIA|TrEMBL
MDSLNATRREAVESRVLESSIASATQGVLGFQQSDGHWVFELEADCTIPAEYILLRHYLA
EPVDTALEAKIGNYLRRVQGAHGGWPLVHEGEFDMSASVKAYFALKMIGDSTDSPHMVRA
REAIHARGGAIHSNVFTRFLLATFGVVTWRAVPVLPIEIVLLPFWSPFHLNKISYWARTT
MVPLMVIAALKPRAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFLLFRSLDAILRVI
EPMFPKSLRQRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKDENYPPRAVTR
RGIDKLLVIRDDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLDWLIPKQELEV
KGDWAVKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGATGYDAAIARGREW
IEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETEKTS
KHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDHKDPMMRKAAAWLAS
IQNKDGGWGEDAVSYRLDYKGWETAPSTASQTAWALLGLMAAGEVDHPAVARGVEYLIAT
QNKKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A4S5D493|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. LS-044|TrEMBL
MNDLTEMATLSAGTVPAGVDAAVARATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNVELEQKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AADGLFPNYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKSIEKLLVVHDDEAYCQPCLSPVWDTSLAAHALLETGDARAEEAVLRGLEWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAVAMDRAQKLRQNDAYRDSIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLI
ANQNEEGLWDEARFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNTTRVTFGL
>A0A7W6CHA8|squalene-hopene cyclase|EC 5.4.99.17|Novosphingobium sediminicola|TrEMBL
MSQTAPDRALLDATIARASQSLLSEQREDGHWVYELEADATIPSEYVLLRHFLGEPVDEE
LEGKIGRYLRRIQSDAHDGWPLYHEGGFDISATVKAYYALKMIGDDVDAPHMARARAAIL
KAGGAEAVNVFTRIQLALFGAGPWDAVPTIPPELILAPRWFPVHLLKMSYWARTVVVPLL
VLCALKPVARNPKQVFVPELYTGVTRKLTSQADHVHAVWKNGFEALDWGLKRFEGRWPKA
MRTRAIRLCEEWVVERLNGVDGLGAIYPAMANSVMMFDVLGYAPDHPHRAIARESVERLL
VVKEDEAYCQPCVSPVWDTALAAHAMLEVGSEEALAGADRALDWLGPRQILDTAGDWVEQ
RYVRPGGWAFQYNNDHYPDLDDTAVVVMAMDRASGLRGDKDAQAIARGVEWTVGLQSKDG
GFAAFDADNDKLYLNNLPFADHGALLDPPTADVSARVVSMLAQMGEPVDSPRMKAALGWL
EKEQEKEGSWFGRWGVNHVYGTWSVLCALGRAGIGRDHPMVARAVEWLKTVQNADGGWGE
SCDSYALDRKGHESFVSNASQTAWATLGLMAVGEAKSEAVARGIAWLIANQAGDGLWGQE
HYTGGGFPRVFYLRYHGYPRYFPLWALARYRNMAQANVEQAQWGM
>K9Z5C4|squalene-hopene cyclase|EC 5.4.99.17|Cyanobacterium aponinum (strain PCC 10605)|TrEMBL
MTAQLTNPNKVEHSKVKSGIKQAQDYLFSLQEKDGHWCAYLESNVTLTAEAVLLYKIWGI
DSHKPLHKIEHYLRSQQREHGGWELYYGDGGDLSTSVEAYMALRLLGVAQEDEALTKAKR
FILSKGGISKSRIFTKFHLAIIGCYDWRGVPSIPPWIMLLPQNPIFTIYEMSSWARSSTV
PLLIVFDQKPVFKIEPKINLDELYSEGKENVKYELPRSGDWTDIFVQLDNLFKFAEDINF
VPFKEESIRAAQKWIIEREEATGDWGGIIPAMLNSLFAFKTLNYHVNDPMVARGLEAVEN
FALETHDDYLVQACVSPVWDTAWCLRALVESGVAPNHPALIKGGEWLLDKQILDYGDWVV
KNPHGKPGGWAFEYENRFYPDMDDSSVVIMTLHQLELPREDLKKEAILRCLRWIETMQCH
NYGWAAFDINNDANWLNLLPYADLKAMIDPATADITARVLEMVGSCDLPMSSSKVQKAIA
FLLHQQENDGSWFGRWGVNYIYGTSGALSALAVIAPQTSQEAMKKGINWLINCQNPDGGW
GETCDSYKNPALKGKGNSTASQTAWALIGLLDAGKALGKFEQDSINKGINYLLSSQTETG
TWEEKEFTGTGFPQHFYINYHLYRHYFPLIALGRFENFLV
>A0A523FTM7|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MSLDAINTSQTRGGSLKERAALKRAVHESIDNGLAWSAKNQTEDGYWVGKLQTNSCMEAQ
WILALHVIGRSDHPIRAGLVRSLLNEQRDDGSWEVYHDAPAGDINTSVECYAALKCAGLD
KDFEPMRKARAWILERGGLKHVRVFTRYWLALIGEWPWQKTPYIPPEVIYFPTWFPFNIY
NFSSWARATLMPIAILSAQRPIVPLEPGSRLDELFPDGRDAFDYSLLKKTELFSLERFFL
WADRRLHGMQNWRLFPFREKTIKRVLDWIVDHQDADGVWGGIQPPWIYSLMALHGEGYAH
DHPVMAKALGALEDPRWTYESDGATYVNASVSPVWDTVLTLLAIQDCDAEAAHGPEIGKA
IDWLLDNEVRTPGDWKVKLPDVEPGGWAFEYANAKYPDVDDTAVALMVLARYSDDPKWQA
KGLPGAIDRAVQWVFAMQCDDGGWASFDKNNDKAILTKIPFCDFGEALDPPSVDVTGHVL
EGLAALGYAQDHPSVARALDFLRAEQEPDGSWWGRWGTNYIYGTAAVLPALKAMGQDMGA
DDVTRAADWILSRQNADGGWGETCGSYMDPRLAGRGDTTPSQTAWALMALLAVGRTQDRA
AIERGLALLIKRQRHGTWHEPHYTGTGFPGYGLGRRINLGRKGLSDDLQQSTELSRAFMI
NYNLYRHYFPVMALGRADKYLARLANEGM
>A0A3M1KJY4|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MDASIQETNRETFDAHLEQVIAEAREGLKRRQRDDGHFLFDLEADATIPAEYIFLNHYLD
EREPELEERLARYLRSIQDADGGWPLFHRGPADLSATVKAYYALKMVGDDPEAPHMRRAR
NLVLSMGGAERSNVFTRYALALFGEVPWKAVPVMPVELMLMPRWFPVTIWRMSYWSRTVI
APLLILAALKPKAINPTGATIRELFRRDPDIIDDWQQNPGGGWIGRFFLGLDRVLRVVEP
HFPKGSRRRAMKAAEDFFIARLNGEDGLGAIFPAMANSVMAMEALGYPKDDPRLVTAKKS
IRLLVTPGEGETFVQPCVSPIWDTGLAAHALMEAGEAPASPVVKRATDWLKSKQILDVKG
DWAVNAPDLEPGGWAFQYANDYYPDVDDTAVVAMALHRTQNPEYDENIDRAAKWIEGMQS
SNGGWGAFDIDNDDDYLNYIPFADHGALLDPPTEDVSARCLSFLAQLGRRRDHPAVSRAI
TYLKKTQQPDGSWYGRWGTNYIYGTWSVLSALNAVGEDMQAPHVRRAVEWLLARQNEDGG
WGESGESYWEEKRDQPAPSTASQTAWALLALMAAGEVAHPAVRRGVEWLLAQPREDNGDR
WVEPWYTAVGFPRVFYLRYHGYAAYFPLWALARYRRLRQANEKKVAWGI
>A0A537MZM0|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MVKPVSSQNPPSAARLDRSIDIAANALLGLQRDDGHWVFELEADATIPAEYVLLRHYLGE
PVDSVIEAKIASYLRRIQGDHGGWPLFRDGAFDMSASVKAYFALKMIGDPTDAAHMARAR
EAIRSRGGAARSNVFTRIMLALFGIVPWRAVPVMPVEIMLLPRWFPFHLEKISYWSRTVI
VPLLVLQALKPRARNPSGVIIDELFLDAPQTVGAAPKALQQKAAWFWFFRAADIALRAAE
PWFPAQSRKRAIERAVEWVSERLNGEDGLGAIFPAMANSVMMFDALGHEESDPRRAIARK
SIQKLLIVHEQEGYCQPCVSPIWDTALTCHALLEVGGNTIQKHVCKGLEWLLPKQILTVR
GDWTARRPHLRPGGWAFQYANPHYPDVDDTAVVVMAMDRAGTGQFAASITRAREWIVGMQ
SRNGGWGAFDTDNEFYYLNNIPFADHGALLDPPTEDVTARCVSMLVQIGDGAESSAIVER
ALDYLRRTQMPDGSWYGRWGMNYIYGTWSVLCALNAAGMDHAAPELRKAVAWLVRIQNSD
GGWGEDGASYKLDYRGYEQAPSTASQTAWALLGLMAAGEIEHLAVERGIEYLLRRQGEEG
FWDEPRYTATGFPRVFYLRYHGYAKFFPLWALARYRNLKNANSRSVAFGM
>A0A7W7IBR0|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura catellatispora|TrEMBL
MTAVETGTRTRTAAEALEAAREHLLLLQSPEGWWKGELQTNVTMDAEDLLLREFLGIRTG
ADTDETARWIRSRQAPDGTWATFHGGPPDLSTTVEAYVALRLAGDPPDADHMMRAAAYVR
GAGGIPATRVFTRFWLAMFGRWPWDELPVLPPEMMFLPRWFPLNVYDWACWARQTIVPLA
VVGALRPVRPLPFGLDELAPFDDVPRNRRRGLPGWDTAFETLDRALHVYERRPVRGLRRA
ALRRAGEWIIARQERDGSWGGIQPPMVYSLIALHLLGYGLDHPVVRRGLDGLERFTIRDA
EGRRIEACQSPVWDTVLAMNALADAGLPEGHPALERAAEWVIGEEVRGPGDWAVRRPDLP
PGGWAFEFDNDCYPDVDDTAEAVIALNRVRHPLAEPAIERGVRWMAGMASRDGGFGAFDA
DNTRGLCRRLPFCDFGEVVDPPSADVTAHVVEAMAHRGMADSLTVKRAVVWLLKAQEPDG
SWFGRWGANHVYGTGAVVPALIAAGVRPGRPEIRAAVEWLELHQRDDGGWGEDLRSYRDP
SWIGRGVSTPSQTAWALLALLAAGERGEAVERGVGWLAEHQRADGTWDEDHFTGTGFPGD
FYINYHLYRLVFPISALGRYLKGA
>A0A840XWQ1|squalene-hopene cyclase|EC 5.4.99.17|Roseomonas pecuniae|TrEMBL
MKDVPDSMLAAPDAAWLEEVEAGVSRAAEALRREQREDGHWVFELEADATIPAEYVLLRQ
HLGEPDDPALEAKIGNYLRRIQGEHGGWPLFHGGALDVSASVKAYFCLKMSGDSPDAPHM
ARARAAILAHGGAARANVFTRILLAMYGEVSWRQVPTIPVEMILLPRWFPVHISRMSYWA
RTVLVPLLVLQALRVRARNPRGVRVQELFAPGRAPRRRVRTHRHPAWSLFFNGIDGGLKV
AEPLWPRRLRRQAIERCVAFVTERLNGEDGLGAIYPAMANAVMMYDALGYPEDHPDRAIA
RRSIEKLLVIREEEAYCQPCVSPVWDTALTAHAMMEVGGETAEATVPRALSWLKPLQELD
VRGDWAEARPHLRPGGWAFQYRNAHYPDLDDTAVVVMAMDRARGQLGLGAGYDEAVARGA
EWTVGLQSSNGGWGAFDVDNVHYYLNNIPFADHGALLDPPTADVSARCLGMMAQLGETPE
TSPRMRAALSYLEREQEADGSWFGRWGVNYIYGTWSALIALNAAGLDGSAPSVRRGADWL
LSIQNPDGGWGEDCESYSLDYRGYEPALSTASQTAWALLGLMAAGEVDHPAVARGIEHLR
RTQDETGLWRQDAYTGGGFPRVFYLRYHGYPRFFPLWAMARYRNLKRGNARRPAHGM
>A0A8J7DVG0|squalene-hopene cyclase|EC 5.4.99.17|Lusitaniella coriacea LEGE 07157|TrEMBL
MQTQDRSTASNCPIIRETLQNAITASQNHLLSIQYPDGYWWAVLESNVTITAEVVLLHKI
WGTDKTRPLHKVETYLRNEQREHGGWELYYGDGGELSTSVEAYMALRLLGVPASDPALLK
AKEFILERGGISKTRIFTKFHLALIGCYDWQGIPSIPPAIMLLPDNFPVTIYEMSSWARG
STVPLLIVFDKKPIYLTEPGINLDELYAEGVENVRYELPKSGDWADLFVGLDKGFKFAEV
SNLMPLREAGLKAAEKWVLERQEATGDWGGIIPAMLNSLLALRALHYDPCDPIVDRGLQA
VDRFAVETEEIYWIQPCVSPVWDTALVMRALVESGMEPNRPELVRAGEWLLDKQILDYGD
WAVKNKKGKPGAWAFEFDNRFYPDVDDSAVVVMALDAVTLPDEELKRSAIARTLKWILSM
QCKEGGWAAFDLDNNQDWLNAIPYGDLKAMIDPNTADVTARVLEMSGRCDLSLGSFALRR
ALAYLIKEQEQDGSWFGRWGVNYIYGTSGAISALALIATESHISNIERGAAWLLSCQNSD
GGWGETCQSYNDPSLKGQGDSTASQTAWALAGLMAAVEASTTVAGSTLTPETLSAIERGI
EYLIATQRSDGTWDESYFTGTGFPCHFYLKYHLYQQHFPLTALGRYQKLMSNPPNCPS
>A0A840VDC7|squalene-hopene cyclase|EC 5.4.99.17|Acidocella aromatica|TrEMBL
MLGMNAILDTAIERARASLVNEQRPDGHLCYELEADATIPAEYVLLEHYLNQIDEPLQQK
IGNYLRRIQGDHATNPGGWPLFHGGKFDLSASVKAYYALKIIGDSPDAPHMAKARKAILA
HGGAERANVFTRIQLALFGAAPWEACPVVPIEAVLMPDWFPFTMRKVSYWSRTVMTPLMY
LTAKKPIARNPRKVFVDELFTRPQAQIRDWIRGPYKSNWGPVFKVLDSVLRVAEPYFPHH
YREKAIDKAIAWTIERLNGEDGLGAIYPAMANSAMMFDHLGDKAHFDIAMGSIKKLLVIK
DDEAYCQPCLSPVWDTALAGHALIESGATDATKAACDWLIPRQELNVVGDWADNTPGTRP
GGWAFQYNNPHYPDVDDTAVAAMLLHRAGDPKYAESISRAREWIIGMQSTNGAWGAFDIN
NDNQYLNHIPFADHGALLDPPTEDVTARCISFLAQLGKPEDRPAIERGIKYLRETQMPDG
SWFGRWGTNYIYGTWSVLCALNAAGVAQDDPMVKRATSWLISKQRADGGWGEDCESYGDA
PAGEFHGYAAQSLPSQTAWAVIGLMAAGLADHDAVRRGIAFLQASQDEQGSWTEQAYNAV
GFPRVFYLKYHGYPRFFPLLALSRYKQLMASNDRIVKFGF
>A0A177GAN3|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter malorum|TrEMBL
MAADGSAHPKTPLSGEDLDRVVQNAHAALGQRQQADGHWVYELEADASIPAEYILLEHYL
NRIDDALEQKIAVYLRRTQSAEHGGWALYHNGGFNLSSSVKAYFALKATGEDINAPHMRR
ARDAILDHGGAERTNVFTRIQLALFGDVPWRATPVMPVELMLLPRKAFFSIWNMSYWSRA
VIAPLLVLAALRPIAINPRQIHIRELFVTPPERVTDWIRGPYRSVWGRVFKGLDSVLRPT
LGLIPSKTHEKAIKAAIDFIEPRLNGKDGLGAIYPAMANVVMMYRALGVPDTAPRAVTAW
EAVQGLLVHKDDEVYCQPCVSPIWDTGLSGHAMLEAASGPKGIAPQETLTELRKASKWLR
DKQILDVKGDWAINNPNVAPGGWAFQYGNDYYPDVDDTAVVGMLLHREGDPANAESIERA
RQWILGMQSRGGGWGAFDIDNNKELLNHIPFSDHGALLDPPTADVTARCISFLAQLGHGE
DRPVLERALTYLRKEQEEDGSWFGRWGTNYIYGTWSALCAFNAAGVSHDDPAVVKAVEWL
RSVQRPDGGWGEGCESYEGGNHGTYGESLPSQTAWAVLGLMAAGRRDDPAVTRGISWLAS
QQDENGEWQEDPYNAVGFPKVFYLRYHGYKQFFPLMAVARYRNLESSNTRRVAFGF
>D5DFI7|squalene-hopene cyclase|EC 5.4.99.17|Priestia megaterium (strain DSM 319 / IMG 1521)|TrEMBL
MIILLKEVQLEIQRRIAYLRPTQKNDGSFRYCFETGVMPDAFLIMLLRTFDLDKEVLIKQ
LTERIVSLQNEDGLWTLFDDEEHNLSATIQAYTALLYSGYYQKNDRILRKAERYIIDSGG
ISRAHFLTRWMLSVNGLYEWPKLFYLPLSLLLVPTYVPLNFYELSTYARIHFVPMMVAGN
KKFSLTSRHTPSLSHLDVREQKQESEETTQESRASIFLVDHLKQLASLPSYIHKLGYQAA
ERYMLERIEKDGTLYSYATSTFFMIYGLLALGYKKDSFVIQKAIDGICSLLSTCSGHVHV
ENSTSTVWDTALLSYALQEAGVPQQDPMIKGTTRYLKKRQHTKLGDWQFHNPNTAPGGWG
FSDINTNNPDLDDTSAAIRALSRRAQTDTDYLESWQRGINWLLSMQNKDGGFAAFEKNTD
SILFTYLPLENAKDAATDPATADLTGRVLECLGNFAGMNKSHPSIKAAVKWLFDHQLDNG
SWYGRWGVCYIYGTWAAITGLRAVGVSASDPRIIKAINWLKSIQQEDGGFGESCYSASLK
KYVPLSFSTPSQTAWALDALMTICPLKDRSVEKGIKFLLNPNLTEQQTHYPTGIGLPGQF
YIQYHSYNDIFPLLALAHYAKKHSS
>A0A7K2K6S2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4937|TrEMBL
MTATTDGSTGAANLSASPAGHPADTTTAADDVLAAARRAAERSVAHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYEGPSDLSATIEAY
VALRLAGDRPDEPHMARASAWVREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPAEPNPPRKLAPAASW
DGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIVERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMVEACQSPVWDTCLATIALVDGGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARLEAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLGSHPRTRRGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALVAAGLPAAHP
SIRRAVTWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDSRAV
ARGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRT
GAAKGA
>A0A5N8VLX7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces adustus|TrEMBL
MTATTDGSPGALPPRAAAASETDITIPAAAGVQEAAEGAARRATDFLLARQDAEGWWKGD
LETNVTMDAEDLLLRQFLGIEDELTTKAAGLFIRGEQREDGTWAGFYGGPGELSTTIEAY
VALRLAGDAPDEPHMAKASAWIRDRGGIAAARVFTRIWLALFGWWKWEDLPELPPEIIYF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPARPNPGGPLAPVTSW
DGAFQRLDKALHALRRVAPRRLRRAALNSAARWIVERQENDGCWGGIQPPAVYSVIALYL
LGYDLEHPVMRAGLQSLDRFAVWREDGARMIEACQSPVWDTCLAAIALADAGLPADHPQL
VKAADWMLGEQVVRPGDWSVKRPGLPPGGWAFEFHNDNYPDMDDTAEVVLALRRISHHDP
ERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVVDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIQWLLAAQEPNGSWFGRWGVNYVYGTGSVVPALTAAGLPASHP
AIRRAVRWLESVQNDDGGWGEDLRSYQDSREWSGKGVSTASQTAWALLALLAAGERDSKA
VERAVGWLVSTQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGEPFSEA
KGG
>A0A6G3AIA1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID2999|TrEMBL
MTATTDGSTGATIPPRAAAASDTDSTDPLAAGVPEAAERAAARATEFLLARQDSEGWWKG
DLETNVTMDAEDLLLRQFLGIRDEATTRAAALFIRGEQREDGAWATFYGGPGDLSATVEA
YVALRLAGDAPDAPHMARASAWVRERGGIASARVFTRIWLALFGWWKWEDLPELPPELIW
FPTWLPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAHPNPPKPFAPLAS
WDGAFQRLDQVVHRLRGAVPRRVRRAAMNAAARWIVERQENDGCWGGIQPPAVYSVIALH
LMGYDLQHPVMRAGLESLDRFAVWREDGSRMIEACQSPVWDTCLAVIALADAGVPADHPQ
LLKAADWMLAEEIRRPGDWSVKRPELPPGGWAFEFHNDNYPDIDDTAEVALALRRVRHPQ
PDRVDGAIARAVRWNFGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMMAAEGLAHDPRTRRGVTWLLAEQEADGSWFGRWGVNYVYGTGSVVPALTAAGLPTSH
PAIRRAVHWLQQAQNDDGGWGEDLRSYKYAREWSGRGASTASQTAWALMALLAAGERYSD
AVERGVRWLAETQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFEK
APLAARRGVRATAGGS
>A0A7W7PYL0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces griseostramineus|TrEMBL
MTATTDGSAGAALPPRVTAASDTDTDTPVAAGVPDIAARAMRRATDFLLSRQDDQGWWKG
DLETNVTMDAEDLLLRQFLGIRDEETTRAAALFIRGEQREDGTWATFHGGPGELSTTIEA
YVALRLAGDPPDAPHMAKASAWVRARGGIAASRVFTRIWLALFGWWRWEDLPELPPELIW
FPSWAPLNIYDFGCWARQTIVPLTIVSAERPVRPAPFPLDELHTDPHRPNPPRPLAPANS
WDGAFQRLDRGLHAVRGIVPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSIIALH
LLGYDLNHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQ
LVKAADWMLGEQIVRPGDWSVRRPHLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHHD
PERVDNAIGRGVRWNLGMQSRNGAWGAFDVDNTSPLPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGLAHDPRTRRGVQWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALTAAGIPRSH
PAIRRAVAWLESVQNDDGGWGEDLRSYRDVRQWSGRGASTASQTAWALMALLAAGERGSK
AVERGVEWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPFTK
KPVLAEAGPERAGATGRESLAEAKGS
>A0A6J4VVG8|squalene-hopene cyclase|EC 5.4.99.17|uncultured Synechococcales cyanobacterium|TrEMBL
MQIQDRVDLSQVKTAIAASQNYLLSIQHPDGYWWAELESNVSITAEVVLLHKIWGTDTTR
PLPKVEAYLRSQQRDHGGWELFYGDGGELSTSVEAYMALKLLGVTADDPAMVRARQFILQ
QGGVSCARIFTKLHLALIGCYDWRGVPSLPPWVMLLPPSSPFNIYEMSSWARGSTVPLLI
VLDRKPSFSVAPAITLDELYAEGRQNAQFELPRSGDWRDLFNLLDYSFKLAENFNAVPFR
EEGVKAAERWVLERQEATGDWGGIIPAMLNSLLALRSLNYAVSDPIVERGLQAVDRFVIQ
TEDTYRVQPCVSPVWDTALVMRSLRDSGLPADHPALVKGGEWLLEKQILDYGDWAVKNQQ
GQPGGWAFEFENRFYPDVDDTAVVVMALAAVRLPNQQLQQAAIARAVDWIATMQCQPGGW
AAFDLDNNQDWLNQLPYGDLKAMIDPNTADVTARVLEMLGHSSSTMEQERIDRALSYLER
EQEPEGCWFGRWGVNYIYGTSGVLAALSLIAPQAQKKSIQRGADWLVSCQNPDGGWGETC
GSYDDPSLKGRGPSTASQTAWALIGLLAAAEATGQRAQTAVQQGVGYLLETQRSDGTWEE
AHFTGTGFPGHFYLKYHLYQQHFPLTALGRYYTQLDQT
>A0A523H8T9|squalene-hopene cyclase|EC 5.4.99.17|Betaproteobacteria bacterium|TrEMBL
MKGLDTLTGVVREDTNFSHTNEISSVHQRSSNRDIARLEDALTAARTALLSLQKEDGHWC
FPLEADCTIPAEYVLMMHFMDDVDVDLETKLARFIRKKQDPKHGGWPLYYGGHFDLSCTA
KAYYALKLVGDSPDAPHMVVARTAILEHGGAARANVFTRILFAMYGQLPWRGVPFMPVEI
ILLPKWFPFHLSKIAYWSRTVTVPLTILCSLRAHAINPRKISIRELFTVDPEEERNYFLL
RTPLNRLFLFIERTALIFEPLIPKSLRRVALHRAECWIVERLNGECGLGAIFPAMVNANE
ALALLGYPYEHPYRKQCRQALLGLLVDEGEQVWCQPCTSPVWDTVLAILSLQEDIGADQK
PIRDALDWLVPLQIHDAPADWQEENPRLAGGGWAFQYTNPHYPDLDDTAAIGWAMHQADP
QAYRESLACAASWLSGMQSRNGGYAAFDVNNTYYYLNEIPFADHGAMLDPPTSDVTARCT
GFLALYGKPEQQNSMKQGLAYLFNEQEPSGAWFGRWGSNYIYGTWSVLEAFRLAKVDTNH
ASINRAVQWLKSVQREDGGWGENNDTYFEPQLAGQFETSTSFQTAWALLGLMAAGETQSQ
EVRKGIEFLLYSQDNDGLWDDPWFTAPGFPRVFYLKYHGYSKYFPLWALARYQAFIQRDL
V
>A0A7C9BIB6|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. BE17|TrEMBL
MNDLTEMATLSAGIAPAGVDAAVARATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKALDKLLVVQEDEAYCQPCLSPVWDTSLAAHALLETGDARAEEAVLRGLDWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLRQSDAYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTSDVSGRCLSMLSQLGETAA
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLGPEDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLI
AEQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNATRVTVGM
>A0A7K2MW35|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID6013|TrEMBL
MTATTDGSTGASLRPLAASASDTDSTIPAAAAGVPEAAARATRRATDFLLSKQDAEGWWK
GDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDSPDAPHMARASEWIRSRGGIAASRVFTRIWLALFGWWKWEDLPELPPELI
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPARPNPARPMAPAA
SWDGAFQRIDKALHAYRKVAPRRLRKAAMNSAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPEDHP
QLVKAADWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHH
DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNT
>A0A3M1IN80|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia bacterium|TrEMBL
MRIGSGAPSGLDEAIERAVAWLARHQEPEGFWVGPLETNSCMEAEWILAMHFLGVKDDPK
LPGVVRAILREQRPDGSWEVYHEAPKGDINTTVECYAALRAVGFKPDDEPLRKARKWILD
HGGLTMTRNFTRFWLALIGEWPWTATPAVPPEMIFLPPWAPFNIYWFASWARATMVPLAI
LSARRPVRPLPPERRLDELFPEGRKHWDYRIFRRIRGFWPFFFRVIEKLLHYYQRSPWQP
GREAAIKLCLEWILRHQDPDGAWGGIQPPTVYSLMALNVEGYPVDHPVLQVGLDAWNHHW
SHREGDAIYIQASESPIWDTVLSLVGLIDSGETFDTFPGMRRAVEWLLDKQILTPGDWAV
RVPGVECGGWAFERANRLYPDVDDTAVAMIVLQRLLPSAPADLRPRMEWALQRAETWVRA
MQSANGGWGAFDKDNTHMILTQIPFSDFGEILDPPSADLTGHKLEALGCMGHSLEDPAVR
RAVDYILREQEPNGSWFGRWGVNFIYGTAMVLPGLRAVGFDMKDPRILKAGRWLVSCQNE
DGGWGESCGSYMEETLHGKGPTTPSQTAWALMALLAIDDPEFDEAIRGGVEWLLRHQRPD
GTWDQEHYTGTGFPGYGIGERIRHKNNLAVLAQGCELARGFMLNYTMYRHYFPLQALARA
REYFRRRRGGTAGGRA
>A0A090Z1Y3|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus macerans|TrEMBL
MGHVISGVGREIGRLTDELVRRQQPDGTWRYCFENGTAMDVSVIVLLRSLSAGSEELIRS
LHDRILAAQQPEGCWRWFEDEREGNLSATVEAYYALLFSGYSRPEDEPIRRARNYIQAAG
GIEMAGGLLTKALLAATGQRKWPVALSSIPLEILLLPPSFPVSFFDFSGYSRVHLVPLLI
MADRDFSLKTPHTPDLSDLYGGGRGFDEEELSRENRDLLAHIQAGIGRLIGSPQRIHQAA
VKKAEQYILERIEADGSLYTYASCTVLMVFALLALGYDRRDPLITHAVDGLAAMRCSAGG
TGGEVTIQNSPSTVWDTALIAYALQEAGLSEDHAAIRKAAAYLRSRQHRKAGDWQIHNPG
VAPGGWGFSDTNTIIPDVDDSTAALRAIHSLAGREPACLEAWNRGLNWVLSMQNDDGGWP
AFEKNTNKEMLTWLAIDGAKAAAIDPSEADLTGRTLEFLGNFARLDARHEFIRRGADWLI
RHQEADGSWYGRWGICYIYGTWAALTGLKAAGLASDHDAVAQGVSWLLSVRNPDGGWGES
CRSDREERYVPLRASTPSQTAWALDALIAVHDRPTAEIDQGIARLIAMLHEDGWTASYPT
GAGLPGYFYVHYHSYRYIWPLLALGHYRKKYGGD
>A0A7V3AEX8|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MEQTARSTRRLKRPKTRLEAWRARLHEVLSGVPGYRALSFPSGAAAAPAAAVDPLLAEPP
VYPRPVVHASGPRISEQGVEAGMRRAAEWLLRDQKPEGYWVAELEADTTLESYFILFKAF
FGQRDHPKIPKYAKTLREAMLPEGGWNIYHGGPAELSVSVLSYFALKVAGVSADEPDMRR
TRDTILRLGGATKANTYTKFHLAFFDQYDWAHVPAVPPEMIFLPAVAPINIYEMSSWSRT
IFVPLSIIYALKPTCPLPKECHVDELFIGGREHADLALPRTREPFSWRNFFLLTDRALKI
AEKFPIQAARRVAIKKAEEWMVQRFEASGGLGAILPAMMNSVFALKCLGYADDHPLVQEG
IRELDALEIHRPENDSIEVQPCHSPVWDTCISVYALAQCGYRQETPQVQRAVDWLLSKEV
RRPGDWQVKNPAPPSGWFFEYENEFYPDVDDTIMVMMALRNVSPRGESKAIDAAIERALF
WVLGMQCEDGGWASFDRDNAKAFLTKVPFADHNAMIDPSTADITSRTLEMFAQIAPEVFT
LNHTVVRRA
>A0A3L7SZ10|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
RHLGGAEHCNSFTNFYLAALGQISWNAVPAIPPEIMFLPKWFPFHLDKVSAWTRAMIVPL
TIVSSRRHTREISVALGIGELFVDHDARDQLTTAPSSSPRWRTFFLGLDALLKKAHNFGG
SPWRQQAIHRAFDWIHARAGQDGAAATDGVGAIFPSMVYWQIVLHALGYERTHPLVARAE
RELDAFFVPLGIGADAPIRIQPCFSPVWDTGIALYALADCGYTVDDEDAARAAAWLTARE
CRFSGEWQNNLDVETAPSGWYFEYANAHYPDSDDTAMVAMALARVGGESNLAAATRGVRW
LLAMQNADGGWAAFDRSHDRPILELVPFADHNAMQDPSCPDITGRVLECLSWQGFSKTHT
AVIAAIAFIKSRQEIDGSFFGRWGVNYIYGTWQAVIGPVRCGVSAKEPWILRAGAWMKSI
QKADGSFGESADSYANPALKGTGPSTASQTAWAAMVLQEVYGADDADLARAIAWLCRTQL
DELSAADPLLNPDGDPSGSWCEREFTGTGFPKVFYLRYHLYRLYFPVMAIGRYLDAHGRG
LAGKRLIDRGERSALFS
>A0A3M2CJT3|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MSPAAATATRAPAVGVRTPPMSIDARARSALDAGVEALLAKQHDDGHWCAELEGDSILNS
EYLLMKAILGQHAPDAAEGATERDRALHRKILAYLRMLQRADGSWGQYPGAAMDLSATVK
GYFALKIWGEDPQAPHMRRARQRILEAGGAERINTFSMFYLACLGQVSWDACPAIPLQIA
LLPRWFPFHMDKVAAWTRTMILPLAICSALRPVRQIDPRLGIDELFVDPRARGRLCKPWD
RDNPVSWANTFIAVDTALKVADRLGLTPMRRAALERAEAWLLERMDPETTDGLGAIFPPM
VYIQVALQALGYARDHPVRRTAECELDRFIVEEADHARIQPCFSPVWDTGIALYALTEAG
LDAGAEPRLARTLEWLCDREVRLTGDWVRNLRPRDRSIRLGVDAAAWAFEHRNDWYPDVD
DTAMVAKAMRRAVRPITLAPASDPSIAEPVGRASGPSVAARAFDASQRATRWILAMQNDD
GGWAAFDRTKDRRWLEAVPFADHNAMQDPSCPDITGRTIEALTTCGVPRDHPAVRRAVAY
LWRTQRPEGWWPGRWGVNAVYGVWQAVGGLHAAGESRDPRLLKTTRWLRSIQNADGGFGE
TADSYEDPRWIGVGPSTASQTAWGAMALMYLAGARDRAVERAIAWFCDHQLNQDCDAEPP
APLDISGLHPAQIAWATSEDRPPVVASHPVPEPAGAWREAWFTGTGFPKVFYLRYHLYRH
YFPVMALARFLRLRHGRIGS
>A0A3L7MYE5|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MREVPHDFIRRPYPERRPLSNAEIEQHLERAVVALKSLQKPDGHWCGELEGDSILQSEYL
LMKWILGQERLPMGDGRPPQTLLRIVDYLRGQQRADGGWGAYPGSPSDLSASVKAYFCLK
LFGDSPEAAHMKKARAIVRHLGGAERCNSFTKFYLAGLGQISWNAVPAIAPEIVFLPKSF
YFHLDKVSAWSRVMILPLTIVSTKRHTRELPVTLGIGELFVDHEARHQLSMRDGAPPFWT
SFFARVDQALKWLHGKGGTPWRHAAIVRAFDWLEAHAGEGGIGAIFPSMVYWQVVLHALG
YERSHPLVVRAERELDRMLVEIGAGADAPMRVQPCLSPVWDTGIALYALADCGFDNFDPK
VARAAEWLVAKECRVAGDWMANLDAPAAPSGWFFQYDNAQFPDCDDTAMVVMALMRAGGD
ANRAAAGRGARWLLAMQNDDGGWAAFDRTSDRRILEYVPFADHNAMQDPSCPDITGRVLE
CFAWHGLTKDHAAVAAGIAFIRGRQEPEGCFFGRWGVNYIYGTWQAVIGPIRCGVARDEE
WIARAGRWMKSIQKPDGSFGESAESYENPALKGQGPSTASQTAWAAMVLQEIYGPDDEDL
RRAISWLCHTQLDRAAANDPISNPDGDPAGSWRETEFTGTGFPRIFYLRYHLYRLNFPTM
AIGRYLAALGRGEQGRRLVATGERAALGL
>A0A535QHK3|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MDNKKPGKGEEPRLKQALDRAVQWLLERQNVEGWWCGELETNVTMTAEHVLLLRFLELGL
ERIRDGAIRHILNNQRDDGSWALYFGGPADLSTTIEAYVALKVLGVDPGSDAMQRALAVI
HQQGGVAQARVFTKIWLALFGQYPWSGIPSMPPELIYLSPKMPFNLYDFACWARGTIAPL
LIVISRRPVKSLGCSVPELVVPGTEDLLTRVPGSGLFWWTDKLLKLYEAFPWQPGRSRAR
RRVVDWIVERQEADGSWGGIQPPWVYSLIALYLEGMGTDHPVMRRGIEGQEGFVLEDESG
WRFQACMSPVWDTAWALLALRHAGVERDHPGIQRAVQWILQEQISVGGDWQVRGGTVPCG
GWAFEFENDIYPDIDDTAVVVLALLEAGAEAAVRTAVDRAARWVLAMQSSNGAWGAFDKD
NTRAIVYQLPFADFGALLDPPSEDVTAHVLEMLAHVDAPDKERVIRVALKYLRHTWCVIS
ALAALRDEGYAVQDMIDRGSSWLLEHQNSDGGWGESCYSYEDSSFAGIGQSTPSQTAWAV
LALQLVGLGQHAACLRGLTYLCETQVDDTWEEREYTGTGFPRDFYINYHLYRHLFPTMAL
AGACKAKVDMAFPFCLP
>A0A7V2JNU2|squalene-hopene cyclase|EC 5.4.99.17|Acidiferrobacteraceae bacterium|TrEMBL
GAARSNVLTRLSLAMFQQLPWRGVPFIPAEIMLLPKWWWFPFHVSKVSYWSRTVMVPLMI
LYSLKARARNPYGIGIQELFTVPPDQEKNYFNIRSRLNLLFLYVERTARLFEPMVPNWLR
NLSIKKAEQWFLERLNGEDGLGAIFPAMVNAHEALAWLGYKEDHPYRITTRKALQKLLVV
GKDSAYCQPCVSPVWDTALAVLALQETGDKKYRSAIKKSLNWLKGKQLLDNDGDWNMQRP
NLRGGGWPFQFANNHYPDLDDTAAVAWAMCQENDEDYRETISRAAEWIAGMQSNNGGYAA
FDADNTRYYLNEIPFADHGALLDPPTSDVSARCLAFLSMVDEPGFEMANKRCLDYLRKEQ
EVDGSWFGRWGTNYIYGTWSVLTALEKAGVSMDDAMVHRAIQWLKQVQRHDGGWGESNNS
YMYPQSAGENSTSTTFHTSIAMLGLMAAGEADSMAAQRGAEYLLHTQLPSGCWHDTGFNA
PGFPRVFYLKYHGYDKFFPLWALARYYKLRSKQVR
>A0A5R9J524|squalene-hopene cyclase|EC 5.4.99.17|Lichenicoccus roseus|TrEMBL
MLTTPDAALSDVALDGAIVAAQSALAGMQSADGHWVFELEADATIPAEYVLLEHYLDRID
APLQTRIGRYLRRIQGTHGGWPLYHDGKIDLSASVKAYFALKAIGDDVDAPHMRAAREAI
LALGGAERANVFCRFQLALFGEIPWHGTPIMPVELMLLPRWFFFNIWNMSYWSRTVTCPL
LVLAALRPRARNPRGIHVRELFRTPPEQVRQWTRGPFRSIWGRVFKHVDDALRLVDPLTP
QILRRHAVRRAVAFVEQRLNGEDGLGAIYPAMANSVMMYDALGVPPDHAGAAIAWRSVRN
LLVDHGEESYCQPCVSPIWDTGLAGHAMIEAASGLSSLPRAESQAATGERLATAGAWLRE
RQVLDVKGDWAVQRPDLAPGGWAFQYRNDYYPDVDDTAVVGMLLHRQDEAANSGAIERAR
AWVVGMQSSNGGWGAFDVDNNHDILNHIPFADHGALLDPPTADVAARCISFLAQLGHASD
RPVIQRGIDFLRREQERNGSWFGRWGTNYIYGTWSVLCALNAAGVPRSDPMMRRAVSWLL
SVQRDEGGWGEDCASFEGAPPGRYNQSLPSQTAWALLGLMAAGERDHPAVARGIAWLTAA
QDGDGEWRELPYNAVGFPKVFYLRYHGYRMFFPLMALARYRNLGQGNSRRVQFGF
>A0A7V4XT47|squalene-hopene cyclase|EC 5.4.99.17|Acidobacterium capsulatum|TrEMBL
MSVSERAQPGGNPLPGSTSPSAVRFGRIDAALEDVKRAIARAKERVFSQQSKDGWWCGEL
EADSMLEADYIFAHTLLGTGDPGKMKRALTEMLRYQNDDGSWSIYPGGPGNISLTVKCYF
SAKLMGMTADNPILVKAREWVLAHGGVVECNTFTKMYLCFLGQYEYDAVPAVPPEIVLFP
NWFYFNIYEISSWSRAILVPLSIAYAKKPFKKIPHEQGIDELFVGGREKANLHLRWDSKN
LLSWRNFFLALDRVTHWFERVYIRPLRSIALRKAEKWMLARFEMSDGLGAIYPAMLNAII
ALRCLGYSLDDPQTLRAMDEFEKLGIDEPEGTAEYPEPTFRMQPCVSPVWDTAQAVFALG
EAGVPRNDPRMLKAADWLLSKEVRHKGDWAMKVRNAQPGGWYFEFNNEFYPDVDDSAQVL
LALNKVDNPRERYQYDVCQRAIDWIFAMQCRNGGWASFDKDNTKMIFQYVPFADHNAMLD
PPTVDITGRILEMLATYGYTRKDRRVEKAIKFIYDEQEPDGSWFGRWGVNYLYGTFLVLR
GLEAIGVWNHEPQIQQAAEWIRSVQNADGGWGETCGSYDDPNTRGVGPSTPSQTAWAILG
LLSAGDDRSDSVAKGIKWLLAHQKPDGGWDESMGSGMKHQAIYTGTGFPRVFYLAYHQYR
DYFPLLALTNYEKAMERGA
>A0A849RL08|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp|TrEMBL
MKLIRTLLDRLSDSFFISAPEKLGLATEPSNIHPLRLVSDNSMPNVSIDAVTRRSTSHSV
SQVDALDDAVRRSQAWFLSKQHASEGYWVAELEADTTLTSEYLMLRRFLDRVDPERERKA
VHYLRAMQLPDGGWPIFYGGPSEISASVKAYFALKLSGVSASETFMLRARDRILAMGGVV
CANVFTKITLALFEQYDWKGVPSMPPEIMLLPRRFYFSIYAISYWSRAVLIPLLIVFANQ
PVCRIPKEQGIDELYLAPRSEIHYRDVPPFNKDQRWFTPHNFFVQLDRVLKLYDTMPLNW
LREKSLQKAATWMLEHIKGSGGLGAIYPAMANSIVALRCLGYQVDDPLVQKSLREIELLE
VYSPVSIGDQRVEALHLQPCHSPIWDTALLMNALIETGLPQDHQALQKAGEYLVSRQTKT
VGDWKFSSPDAEPGGWYFQFENEFYPDVDDSAVVLMALSKVRLDQPVELQESIRRGMNWV
LAMQGSDGGWGAYDKDNNRVVFNYIPFADHHALLDPSTSDLTGRCLEMLAALGYDHTHPA
VGPALRFLKREQEADGSWYGRWGVNYIYGTWSVLAGLHAIGVDLSEPYVLRAVAWLESKQ
NPDGGWGESCLSYHDDPEWSGKGESTPSQTAWAIMGLMSAGMVDAFSVARGVQYLLRQQM
KDGSWEEVRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRTRGKMRADEVRQQVLASG
CYRADR
>A0A5R8QKP9|squalene-hopene cyclase|EC 5.4.99.17|Methylocystis sp. B8|TrEMBL
MNAAARIDDNFTAVSTETLESSIQSAKRALLSLGKGDGHFCFELEADTTIPAEYVLMRHF
RAEPVDAELERKIGVYLRRCQGDHGGWPLFQDGPFNISASVKAYFALKMIGDDIDAPHMA
RARAAILAYGGAAKTNVFTRSLLALYGEIPWRGVPVMPVEIMLLPRWFPFHLDKISYWGR
TVLVPLLVLMTKKPRAKNPKNVHIRELFTTPPEEVKVWPKGEHQTWPWAHIFGEIDKLLR
VIEPYMPKGPRDRSIELAIEWTTERLNGFDGLGGIFPSMVNSLLMYDVLGAPEDDERKKQ
ARESIERLLVVNDMEAYCQPCVSPVWDTCLTAHALLETGDEDAREIARAACEWLAPLQVL
DVKGDWAATRPDVRPGGWAFQYANAYYPDVDDTAVVVTAMDRLTANDASRPYDERIARAK
EWIIGMQSRDGGWGAFDADNTYHYLNHIPFADHGALLDPPTADVSARCVSMLAQLGDTID
TSECLKRGVDYLIKEQEKDGSWFGRWGANYIYGTWSTLCALNAVGLPHEHDAYRRAVAWL
VAIQNEDGGWGEDLSSYKLDYKGYEKAPSTASQTAWALLGFMAAGEVDHPAVARGIAYLQ
STQNEGGLWNEARFTATGFPRVFYLRYHGYGKFFPLWALARYRNLKRANSKRVQVGL
>A0A6L8Q794|squalene-hopene cyclase|EC 5.4.99.17|Nitrospinae bacterium|TrEMBL
MENMIIEQQNAEASNTAGDVAKNELDRSIERSREFLLSRQTEEGYWVDELEANVTISAEY
IFFMHFTDRLDLAKQEKVVKYLLHQQREDGSWPLFHGGLCDINSTVESYMALKMAGLPAD
REEMVRARQAIFANGGIKNTRVFTKIFLAMFGQISWDVCPAVPVELILFPNWFPFNIYEI
SSWSRGTVVPLSVVRSFEPVHDLPEGCDVQELFTKNDQDLDFKPSGLPFTSWRDTFIYLD
RLIKTVGKFPWKPFRKKALRKVEEWTLDHQEEEGDFGGIQPAMFNSLLAFHLLGYSRDHA
ACVKGMEAVDRFMLEKDGRMWMQACVSPLWDTAICSNALLDSGLPSNHPALVKSAEWIIS
KQVVKRGDWQVKNPDAEPGGWAFEFYNELYPDTDDTAEILLFLNRAEVPDNRWKLSECHR
AMDWLLSMQSKNGGWGAFDVDNDKEVLNEVPFADHKALLDPPTVDVTSRIIWMLAKWGFT
KDHPRVKRALEFVKDRQELDGCWFGRWGVNYIYGTFLALNGLKAIGEDMKAPFSRKAVRW
LESHQNEDGGWGETCQSYAEPSLRGRGQSTASQTAWALLGLLAAGEEHSPVVEKGVRYLI
ETQKDSGEFSGSWWEEEFTGTGFPIHFFIKYHMYQHFFPLMALSRYRRSTTESS
>A0A3M1R8S9|squalene-hopene cyclase|EC 5.4.99.17|Nitrospinae bacterium|TrEMBL
MKISKRFYPSILQNLFSLASSPSPVSRLVPDVSSEEAGTVAATRAGGERTRFGVPSSHLE
EAIQRAQDYLVKLQHADGYWVAELEANTTLTSEYIFFLHMLGLVDQRRIEKAANYLLQTQ
QEDGGWNIYHGGPSRLSQTVEAYFALKLAGKSPEDPALQKARHWILSQGGIPQARVFTKI
FLALFGQYDWRGIPSMPVEMILFPQGFYFNLYEFSSWSRSVIIPLLVIMAKRPRYPLPPG
AEVDELYPEPRQGTCYALPPAARRLSWHNLFLHLDSLLKLYEKRPLSRLRQRAMVEAEHW
ILSHQDITGDWGGIMPAMMNSILALHCLGYPLSHPVMRKGLEAIERFGIEEEDHFRLQSC
VSPVWDTAISTLALRYAGLPPHHPVLQKAGYWLLQKQIFRGGDWRVKNRTGRPGGWAFEF
ANDFYPDNDDTAMVLMALQQVDLPVAKAAGLQHLLSPEPSLPEQRVAPYDKAWAMERGVE
WLLSMQGKDGGWGAFDVDNNKRLLNEIPFADEKALIDPSTSDLTGRVLEMLGRLGYTLSF
PPARRALRFLQRDQHPEGPWYGRWGVNYIYGTWAVLEGLRAIGENMQLPYVRKAVEWLKA
HQNEDGGWGESCLSYEDFRHAGQGESTASQTAWAVMGLVAAGEVHSQAVQRGVAYLIQTQ
NREGTWEEEAYTGTGFPGHFYIRYHLYRHYFPLMALAKVRNVLTTGKHSPP
>A0A3N6AR86|squalene-hopene cyclase|EC 5.4.99.17|Priestia endophytica|TrEMBL
MWTKQAKQHTTHLIKELRELQQENGSWHFPFETGVMSDAYMILTLRALGIEEEPLIAKLS
KRILSLQHKDGTWRHYEDEPKGNLSATIQAYTALLVAGASSKEETHMKRAERFIQQNGGV
KKAHFLTKWMLCANGLYPWPRFFYVPMTIMNIPTSFPLNFFSLSAYARIHFVPMMIAANK
KFSIPSNHSIYSLYEREGTEEEWNVEDERFIIKDLLFYLKRLRNLPSYMHQSGYKKAESY
MISRIEDDGTLYSYATATFFMIYGLLALGYEKTSPLIINAVNGLKKLVTTVDDMDHLENS
TSTVWDTALLSYSLQESGVSYKDPMIKKASFYLLNKQHKKVADWAVHNPHIAPGGWGFSH
NNTINPDLDDTSAALRAITAPSVHDTRYLSSWNRGVDWLLSMQNRDGGWAAFEKNVDFQL
LTHIPLKNAEDAIIDPSTADLTGRVLQFLGKFAGLTEKHPAVKRAVKWLCDHQEKDGSWY
GRWGVCYIYGTWAALTGMRAVGVPLDDPHIQKGVLFLKKHQRQDGGWGESCRSSEVKKYV
PLLFSTPSQTSWALDALLTCLPKEHVTIKNGVKFLLTPHIHKAKTYPTGIGLPEQFYIRY
HSYNYIFPLLALSHYCQA
>Q1XAH3|squalene-hopene cyclase|EC 5.4.99.17|Acidothermus cellulolyticus|TrEMBL
WVYSLIALHLLGYPLDHPVLRRGLDGLNGFTIREETADGAVRRLEACQSPVWDTALAVTA
LRDAGLPADHPRVQAAARWLVGEEVRVAGDWAVRRPGLPPGGWAFEFANDNYPDTDDTAE
VVLALRRVRLEDADQQALEAAVRRATTWVIGMQSTDGGWGAFDADNTRELVLRLPFCDFG
AVIDPPSADVTAHGRR
>A0A8J2FTF6|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Methylacidithermus pantelleriae|TrEMBL
MEERVEKKVTALEERKVLPFSLIETARDLEGEAERAVGKAREFLLSLQREDGHWVFELLV
DSTVVSDYLAFHHWWGKIDFEKQARFVKHILDRQLPDGGWSIYPEGPSELNATVKAYFAL
KLGGLSSDEPEMARARSTILRLGGLPACLTYTKLGLALLGVYPWEHLPSIPVEIILFPPW
FPFSIYDLSSWTRGMVVPLSVLHHFKPTRFLPQDKQLQELFPYGTNDKTVLPFSFAWGKR
VVSKRNIFLAVDRVLKVTEQIPWKPLRAKALAKAEAWILERVGEGSDGLGAIFPAMLYAL
AALRCLGYPDEHPVVKKAWRDLEALEVWDEKNADFRVQPCVSPVWDTAITMIALSESGLP
PDHPSLRRAAEWLLSREVRFRGDWRFKNPFPEGSGWAFEYNNIYYPDVDDTAMVLLALLR
SESSDPQAHLKAVERAFRWVESFQCSDGGWAAFDKDVNKKWLENVPFADHNAILDPPCCD
ITARVLELCGRLGVKRTLPMVQRAIRFLRRHQTEDGSWYGRWGVNYIYGTWQVLRGLEAL
GMDMNQPWILRGRDWLESCQNEDGGWGETCASYTQPELKGRGPSTASQTAWALMGIMACG
DLERPSVERGIAYLCSLQNDDGSWTEDFITGTGFPGVFYLKYDSYRNVWPLLALSEYLRR
KRGQKQIAASWARSLLTLAEWRSKRQEGSTP
>A0A534T6C0|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MSASEGRLTLVGGTAGEGLAARVAQAITRASQYLFATQHARGYWHAPLEANATMEAEYVF
FNRLLGRERPDVERRLAERLLALQQADGSWPIYHNGPGGPSTTIEAYFALKLTGMSATEP
ALVRARDFILGRGGLARAGVFTRIWLAYFGQFPWAGVPSMPVELVLLPPWFPLNIYAMSS
WARGTVVPLTLLLAHRPSVRLPAEAAVAELWLRAPTRDDLAFARSPELVTTRNFFLAVDR
ALKTLAPLSWRGLRRRAVARAIEWLLRHQDTNGQWGGIQPAMVNSVLALHAVGFAADHPA
MMSGIQGVEDFLVECEGTLMYQPCVSPNWDTALAARALLDAGLDPAHPALGRAAEWLVAN
QIFRPGDWAVLNPTLEPGGWAFEFANDWYPDVDDSAVILTVLDALPAAETAAGRRAIAYG
LNWTLGMQSRNGGWAAFDTDNTAAFLNRIPFADMEAMIDPPTEDVTGRVLHLMGTIGYRL
DFGRARRAVEFLRRTQRSDGSWWGRWGVNFIYGTWGALAGLERIGEDMRAPYVRRAVEWL
ATHQNPDGGWGETVASYDDESLAGKGESTPSQTAWALLGLLAADGPSSPAVERGVDWLVR
TQGPDGTWQERLFTGTGFPRHFYLRYHLYRHYFPLMALGQYRARLAARGEG
>A0A5J5LUY0|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa EAWAG127a|TrEMBL
MQIQEKITEIAAKTAKAIELSQNYLLSTQYSDGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKAVDNFAIQ
TDNTYCVQPCVSPVWDTAWVIRALIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKAVIKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVKMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNQYRHQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A534NM28|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MVRGAEPAPAARRVVIGARTRIERSGLDLVIERAQGWFERQQYPEGYWWAELESNATMDA
EYLLLTHFLGARNEHLWRGVAQDIRNYQRDDGSWAMYHGAPGDVSTSIECYFALKLAGDR
PDAPHLVRARAFIRERGGIARARTFTRIWLALFGQWSWDELPIMPPELMLLPPSAPLSIY
RFSSWARGTIVPLLLLMDDRPVHPVPDSARLDELRVADAAPRVPRDAIDRLFRGIDGALR
AYDRLPFHPFRERARKAAEQWILAHQEADGSWGGIQPPWVYSLMALHALGHPLDHPALKK
GLLGMHGRWMLRHGDGRLRVQACLSPVWDTGLSLLALVESGVHPSVPMVQQAARWLLREE
IRVPGDWCVQVEGVEPSGWAFEFENDLYPDVDDTAVVLLALHKADALDAETRERALRWVL
AMQSRNGGWAAFDKDNTSRLPALIPFADFGEMIDPPSADVTGHVVETLGAFGLARSHPAM
ERGLRYLYAHQEKEGSWFGRWGVN
>A0A4R9MKU9|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. USMB20|TrEMBL
MNDLTEMATLSAGTVPAGLDAAVAGATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELERKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPIAKNPRGVRIDELFIDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AVDGLFPNYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKALEKLLVVHEDEAYCQPCLSPVWDTSLAAHALLETGDARAEEAVLRGLDWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLRQTDTYRDSMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLI
AQQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A7K2ACQ6|squalene-hopene cyclase|EC 5.4.99.17|Acidimicrobiia bacterium|TrEMBL
MTTARGALAALPWLASAAGAGDFEGDAADALARSVDALAGLQDPAGWWKGDLETNVAIES
EDLLLRAFLGIDDEEVTAPTANWIRSKQNPDGGWSNRYGGPSDLSLAVEAYAALRLAGDS
PDAEHMRLAAEFVRDMGGLECARVFTRIWLALIGQWSWRDLPAIPPELILLPRWLPLNIY
DFACWARQTIVPLSIVSTYRPQVDLGVTLDELRTGAVPPERVPRSVRTPAGCFQRLDRVL
HKFHALAPWRLRETSMKLAEQWIIRRQESDGCWGGIQPPWIYSIIALHLRGYPLDHPILA
KALACFDSYEVRQGDMRWMECCQSPVWDTALAVVALGDAGLRRDDPAMTAAADWLLDEEV
QVRGDWAARRPHLAPGGWAFEFHNDNYPDLDDTAEVVLALGHAQAGDSERANAAIARAVA
WAEGMQCSDGGYAAFDADNVRRLCEQLPFCDFGEVIDPPSADVTAHVVEMLCWVRAHTDI
PVDARRLRRAVDWLWLDQESDGSWFGRWGVNHLYGLGAVLPALRAAGVPTSDRRIRRAVR
WLHATQGPEGGWGEDLRSYESDHWRGRGDPTASQTAWALLALMAADEFGEPTRRGVAWLA
RTCRPDGTWDEPQYTGTGFQGYFYINYHLYRQVFPTMALGRFLRATAGEAPSR
>A0A5D0THE5|squalene-hopene cyclase|EC 5.4.99.17|Micromonospora sp. WP24|TrEMBL
MTELLSAKTATVDSGPLAGPDPLDGAREALRRAREHLLGLQDDEGWWKGDLATNVTMDAE
DLMLRQFLGIRTAQQTDETARWIRSQQLPDGSWATFHGGPGDLSTTIEAYVALRLAGDTV
EAPHMAAAAAFVRAHGGLAASRVFTRFWLAMFGHWPWSRLPAVPPELVLLPSWMPFNVYD
FACWARQTIVPLSIVRALRPVRSLGFGVDELRTSAPPPRPPRLGTRPGLLHRLDRLAGSY
ERIARGPVRRHALRRAAEWIVARQEADGSWGGIQPPWVYSLMALNLLGYPLDHPVLRAGL
EGLERFTIRTRTPDGPVRWLEACQSPVWDTALAVTALADAGLPAGHPALERAGRWMLDEE
IRVRGDWAVRRPNTPPGGWAFEFHNDGYADTDDTAEVIMALRRTGVPVEPAVLRATRWML
GMQCRDGGWAAFDADNTRKLLADLPFCDFGEVTDPPSADVTAHVVEALVAENYAGTLPVR
RGVHWLLRAQEPDGSWFGRWGANHVYGTGAVVPALVAAGVPRRHPAIRRAVDWLLAHQGA
DGGWGEDLRSYRDPSWVGRGESTASQTAWALLALHAAGHGTGEPALRAVRWLVRTQRPDG
GWDEPHFTGTGFPGDFYINYGLYRLVFPISALGRILDTRAGDLEATVTR
>T2AYA0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGLAMHAVLETNSVPDKIIIEKAANWLVERQILDVIGDWAANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARSIVYLKRGQEVNGSWYGRWG
>T2B0G8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVAVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLERGQEANGSWYGRWG
>T2AZP3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANLVLGKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWYGRWG
>T2AZT2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKTIMGKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDRYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAVGYLKCGQEVNGSWYGRWG
>T2AYL7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLAMHAVLEANSEPDKTTMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGSWG
>T2AXW6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIRYLKRGQEANGSWFGRWG
>T2AXU8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSMSDKTIMEKAANWLVERQILDVIGDWGVNAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRAGPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVVRATGYLKRGQEVNGSWFGSWG
>T2AZC7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGLAMHAVHEANLVLGKTIMEKAANRLVERQILDVIGDWGANARGVRPGGWAFQY
WNDHYPDVDDTAIVVMALHRVDPNRYSEAIERGAEWIIGMQSGNGGWGAFDKDNVHHFLQ
HIPFADHGALLDPPTADVSARCLSMLAQLGYGYETEANSRVVAYLKREQERDGSWFGRWG
>T2AXN5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAIATIALRDAGVPAEHPSLKRTVDWLLDKEVRRSGDWTVRNSETEPAGWYFEFN
NEFYPDVDDTCMVLMALARCLPNQPEWDADFLVDDWSPHEADKDVTAVLAARNADSVLAA
VQVDGLRPMLGAMHRGARWILAMQSKDGGRGTFDRDNVRKLFTQVPFADHNAMIDPSTAD
LTARMLEMFSYLNVPADHPVVRRAIDFVWKDQDPEHCWFGRWG
>T2AYB1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSRAPIEIGYKQHVSTEIETALNWLEEQQLNEEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNDKRYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
DEIPSADHGALLDPPTADVTGRAITLLSLADKKIYEKNIKDGVDYIKSEQEEDGSW
>T2B025|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLAVHAMLEAGEPKNGARLNKAMRWMADRQVCDVSGDWATHRPGLQPGGWAFQY
ANDHYPDVDDSAVVAMALDRASDPKVKQGLPRAVEWIVGMQSKNGGWGSIDAENSHYHLN
HIPFADHGALLDPPTEDVTARCVGMLAQIGDEAGNDAIERGLSYLRETQQPDGSWFGSWG
>T2B0A3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLTGISLLESGLTLKNVAIQKACKWLEKKQILEMKGDWVVNNKNLLPGGWAFQY
ENDFYPDVDDTAVVGMFLDRAGYQNKKRLEKACNWIAGMQSKNGGWGSFDKDNTDHYLNN
IPFADHGALLDPPTADVSARCVSMLSQINKKNYNNEIQKGIKFLKDEQEEDGSWFGSWG
>T2AZM3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAIIEICLHAAGVPADSDKLNKTTDWLLDREIRFRGDWKFKNPTDVEPSGWAFEY
ENKWNPDVDDTAMVLMALRRVPGSDRQRRGIAIERGLKWMLSFQCKDGGWGAFDKDCTKD
ILNKVPFADHNAMLDPECADITARILEFMGQEGYGTDDPQVKKAIQFLRDNQE
>T2AYV0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTCIAQLALLESGIDPEDPMVQSSARWLMDKQIYAAADWQVRAKGTRPGGWSFVFD
NLIYPDIDDASIVVMALDQVRLPEAEEPRRADSIQRGVEWMAGMQSKNGGWAAFDKDDNK
KYLTKIPFSDFGETLDPPSVDVTAHLLEMYGRLGYTKEDRAVDRGFAYVISEQEEDGSWY
GRWG
>T2AZS8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAALALQEANPKATRHSREKAYNWLKTKQLDKQPGDWQIQQPHLNGGGWAFQF
ENPHYPDVDDTAVVAFAMANACDLNNLEESIHRATHWTAGMQSKNGGFGAFDCDNTDYYL
NHIPFADHGALLDPPTADVSARCAMLLGHQLNSHPEYQKTLDKTITFLRKEQESDGSWYG
RWG
>T2AZW9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLATHAMLEANLSSGPRILENDSTSKACKWLEKLQIKDCAGDRAVWRPNLRPGG
WAFQYHNDYYPDIDDTAVVAMALHRTGNKIYEPALLRAAEWIIGMQSKNGGWAAFDADNE
YHLLENMPFADHGALLDPPSVDVSARCISFLTQLGHDQTNGTIKRGIEYLKKNQEEDGSW
FGSW
>T2AYP2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTALVSQALIETEYKQHVSTETETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSHSEPIQRAANWVAGMQSRGGGFSSFDINNTHLYL
NEIPSADHGALLDLPTVDVTGRAITLLSLADKKIYANNIKGGVDYIKSEQEKDGSWFGRW
G
>T2AZW0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAICANALLDSGLPADHPALVRAGEWIISKQVTKRGDWQVKNPNAEPGGWAFEFY
NELYPDTDDTAEILLFLNRIEIADNRWKLSECQRAMDWSLSMQSKSGGWGAFDVDNDKEV
LNEVPFADHKALLDPATVDVTSRILWMLAKWGFNKQHPQVKRAIEFIKERQEIDGCWYGS
WG
>T2AYT0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PMWDTAICSNALLDSGLPTDHPALVRAGKWIVSKQATKRGDWQVKNPKAEPGGWAFEFYN
ELYPDTDDTAEILLFLNRVEILDNRWKLSECQRAMDWLLSMQNKSGGWGAFDVDNDKDVL
NEVPFADHKALLDPPTVDVSSRILWMLGKWGFNKQHPQVKRAIKFVKERQEVDGCWYGRW
G
>T2B0D0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTAIVLRGLAEIASPAVDSSNSLANAVDWLLAREVRFAGEWSRRVQAVPSGWCFEY
ANCYYPDVDDTAMVLIAFSSWLKRHKACRGSQEKASEDSQGERIRHIRNAMRRGIQWLTA
MQNSDGGWGAFDRDNNHELLCKVPFADHNAMIDPSPPDLTGRVLEAYGSLGHGVGEPGVD
RAIEYLRETQEPDGSWYGRWG
>T2B0D8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLNGLSLLESGLTLKDSSIQKACKWLEKKQILEIKGDWIVNNKNLLPGGWAFQY
ENDFYPDVDDTAVIVMFLDRAGYQNKKRLEIACNWIVGMQSKNGGWGAFDKDNTYHYLNN
IPFADHGALLDPPTADVSARCISMLSQINKKNHKKIIQKGVKFLKNEQENDGSWFGRWG
>T2AY23|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAICLNALIDSGVPTDHPALIKSAEWILSKQVVKRGDWQIKKPHAEPGGWAFEFY
NELYPDTDDTAEILLALNRIDVPDIRWKLNECQRALSWLLNMQSKNGGWGAFDVDNDKEV
LNEIPFADHKALLDPPTIDVSSRILWMLSQWGFKREHPQVARALKFVKEEQELDGCWFGR
WG
>T2AYB3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLATHAMLEANLSSGPRILENDSTSKACKWLEKLQIKDCAGDWAVWRPNLRPGG
WAFQYHNDYYPDIDDTAVVAMALHRTGNKIYEPALLRAAEWIIGMQSKNGGWAAFDADNE
YHLLENMPFADHGALLDPPSVDVSARCISFLTQLGYDQTNGTIKRGIEYLKKNQEEDGS
>T2AY80|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELIGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAITLLSLADEKIYEKNIKDGVDYIKSEQEEDGSWYGRW
G
>A0A0H2WAB2|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia mallei (strain ATCC 23344)|TrEMBL
MHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHYLGEAPN
VELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQRARRAI
HAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWARTVIVPL
LVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLRLVDGLF
PRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAIARRSIE
KLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQILDVRGDW
ISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAREWVVGM
QSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSASSEPAR
RALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWLLSIQNA
DGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDNPAVARGVDYLLGTQREH
GLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANAMRVTVGM
>A0A5P0YW38|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces alkaliterrae|TrEMBL
MTTDATSPAASVERALDLAVGALRRGQDPTGYWKGDFESSLIGESGEVILRHFLGLPRDE
VTAEAAKTILAEQSATGGWASYHKGPDELLLSVFCYVALRLAGHEADEPAMRAAAASIRE
AGGIEAVDNPTMLAWLSVIGVWPWYDIPIIPPEVILLPSWFPGNIYQVGAAARGIVVANS
LFMAERPVTPAGFHITELFKRPDRGFRRLPRPRALRIATRLSHWYNRNPIGFLRRRAVRK
AADWLVRTQETDGSWGGNWPQTANVVMGLDTVGYRQDHPVIRKAMAALDGYVVHKNGQRR
IEMWTSVVMDTALGVSAAAMSGDPKARESADNAARWLLDTQVTELGDWAVLTKDPVAGGW
PYEFVNRTNPDADDTSFAVVALRRLHPRGTDATVDDAVDRACRWMLSQQCDDGGWAAFEP
LRWRLPGRDHLAKIGFLEAPSADITGHVLEALGADGQGGGEAARRGVEWLRRNQHEDGSW
PGWWACYHLHGTSAAVTGLTACGVPGTDPVVARACDWIEAHQQADGGWGEDIRALRDPAW
IGKGESTPSQTGWALIALIAAGRADSDAVRAGLDHLIRTQEADGDWPEPWHTWVVHHDGL
YWRDSMLRLIYPIMAMAAYRDHAAASGTTDATGEAR
>A4FHS1|squalene-hopene cyclase|EC 5.4.99.17|Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)|TrEMBL
MTEEVLQRTAAPAEVLAAAREHLLSLQHERGWWKGELETNVTMDVEDLLLRRFLGILTTA
ETEQAARWIRSRQRADGTWAQFHGGPGDLSTTVEAYVGLKLAGDDVDSEHMAAARAWILE
RGGIEETRVFTRIWLALFGEWSWDDLPAMPPELVLLPPWVPLNLADWGCWARQTIVPLTV
VCTLRPRRDLGVGLAELRSGRRRRKVPSPSWAGAFQVLDGALHGYQRHPLRGLREHAMRR
AAEWIVARQEADGSWGGIQPPWVYSLLALHLLGYPLDHPVLRQGLAGLERFLIREETPEG
TVRRLEACQSPVWDTVLSMQALRDAGLAADHPALRRAADFVLAEEIRVKGDWSVRRPDLA
PGGWAFEFDNDGYPDIDDTAEVVLALNRVDHERPGAVNAAIDRGVRWMSGMQSADGGWGA
FDADNTRELVNELPFCDFGAVIDPPSADVTAHVVEALCVLGRGDGEAVRRGVRWLLDHQE
LDGSWFGRWGANHVYGTGAAVPALVRAGLRRDHLALRRAVRWLEVHQNDDGGWGEDLRSY
DDPVWVGRGRSTASQTAWALLALLAVDLHDTDAVRRGVGFLAETQRPDGTWDEPQFTGTG
FPGDFYINYHLYRLVFPVTALGRYEQARREQSGGSG
>A0A7W7FUZ7|squalene-hopene cyclase|EC 5.4.99.17|Crossiella cryophila|TrEMBL
MNSTELTGRASVGVHKAVENLYTRQRPDGAWTDRLSSSTVSTALGLLALAKADRERYRER
LERGMDWLRAHQRADGGWSMADAHPPSSPGMTAFAIAACHELDPEGCRERIAKGFAFIEA
NGTDAVIPGMRGPGPKTWPAAAPFALSLVGLRDITEQPTLPVEVMLLPPRLRNKVSIGMP
AVLALGLMQARVLPASPPRRLLQRLAQPRALAWLRAVMAPNGGVEECPMLSALIFLGLQA
ADLGPDLQQGSLDYLLDTQREDGSWAIDRDLEIAVTCYSVLALAEHTDVAADPRLRPTRD
WLLSTQWTEPFRPLKIPAGGWSWNVPSGWPESEDTAVVLSTLGLLGLDRTHPGVAAGLRW
LRVRQNRNGSWSEWVRNSFILNDKPCTGVTAHVLMAMHQHNEPRSRWAPIDRGLRWYEKD
QLPDGSLPSLWFRDGTHGTAKVLETYAELGIPQDPVARRATQWLWDNQAPSGGWPLSVQT
SAPGETAEETAWAVYSLLRAGESPWDPRVLRAVDWLLDRQDEQGSWAPSPTGLYFEDLCY
SDDLITHAYTLRALARWLRQAERT
>A0A4V0YEZ6|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus protaetiae|TrEMBL
MTIDHELREGIAWMSRRLLAQQHSDGSWRFPFDSGTSPDAYLLIVLRTLEIDNEPLLRKL
HDRLRSAQQPDGSWKVYPDEEQGNLAATVDAYYALLYSGFSHAGDEQMQLAKQFISEQGG
LRKVDSVLTKAFLAATGQYPWPASLVLPIEVLLFPNHFPVNLYDFSSYARVHFIPILLLA
DRRFSVTTPISPDLSELSATRSELTWEWRPSGDGSRPMDTWVDSLKQAAGSLAGYPAQLR
EDARRKAERYMLDRIEPDGTLYSYGTATLLMILALLSLGYDKRHPVIMHAVDGLLRTLAV
TDDGAYTFMQNTPSAVWDTALLSHALQEAGVPADHPAIQNASAYLLGKQQYKRTDWAVHN
PIDIAGGWGFSDSNTLNPDVDDTTAALRAIHRLAAKDEHHTDAWNRGLNWILSMQNKDGG
WAAFEKDTDKEWLSWLPIHGARDVATDPSTADLTGRTLEFLGSAGLNHERFACIRRGTEW
LMRHQEKDGSWYGRWGICYIYGTWAALTGLSAAGTIPQHPSVQRAVGWLLSIQNEDGGWG
ESCSSDVKRHYVPLGASIPSQTAWALDALIAVHPRPTSAIDKGIRLLLDMVRSPHGWTSH
YPTGGGLPGLFYSDYYSYKSIWPLLALARYQKKYLHS
>A0A7K2QYC4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5471|TrEMBL
MTTTADDAPREKGPLPAAEEEAARRAVRRAADHLLSRRHTGGWWEEEFTTDVSYDAHDLF
LRHVLGILDERVATAGGRWIRSQQSADGSWPLVFGGAGHLGTTVQAYVALRLAGHRPDED
HMGRCAAWVREQGGVAAAPLEAHVWLAMCGLWCWDDLPEIPPEIIALPTWAPLNIYAFSS
IMRQALVSLGVISAYRPVQPVPFGIDELFVPSDGTPVRPVSAPITRWAGVFQRANTVLRA
GRRITPRAVRRIATNMCARWLLERQETDGSWGACTPITTWVTLALHLHGYAPDHPVLKAA
LRFLDESASWPEDDMRKLRTVRSPVWDTGLAVTALLDAGLDAGHPALVGAADWLLARQSD
RPGDWTARRPRLAPGGWAFQFHNRTYPDNDDTSEVVLALLRIEHPDRARVDDAVRDAVRW
CLGMQSADGGWAAFDVDNASALPGKLPFFDFGEYCVDAPTADITAHVVEMLAAAGMADDP
RTRRAVQWLLGRQEDDGAWFGRWGVNHVYGTGCVLPALIAAGTPCGHPAVRRAVTWLTSV
QNDDGGWGEDWESYADPGRVGRGPSVPSQTAWALLALLAAGERDSAAVRSGVRWLTGRQT
DDGTWEEPEFTGVLVPRAVACRYGYYRHVFPLMALGRYVHRRDAAATR
>A0A5D4SG38|squalene-hopene cyclase|EC 5.4.99.17|Bacillus infantis|TrEMBL
MKNRNKGAGCMQLVKSEIERLKQQLLSEQTPDGSWNHPFDTGCMTDIYMIVLLRTLEEED
EEELIKELAKGILSRQGKDGAWRLFHDHHEGSLSLTIEAYYALLYSGYYEKNHPALVKAR
RVITKGGGLKKAGMYTKIMLALTGQYPWPLLFPVPMEVILLPRSFPLNMYDISVFGRSNL
IPVILLGNKKFSRKTALSPDLGDLCVRDDDDPWPELRSAEWRSLTSFLAAGVKALVGIPR
QIRAWSIEKAREYMQSHTEPDGTLYNYFSSTFYMIFALLALGGGPEEPAIRNAVAGLKRM
TVKADGRKHIQYTTAAVWNTALISHVLQEAGVPPKEDAIQKANQYLAGQQHRRFGDWIVH
NTKAEPGGWGFSRFNTINPDVDDTTAALRSLHQPAREKPHYDDIWKKGLLWTLSMQNRDG
GWPAFERNVDKKLLHLLPIQGAEFILTDPSTADLTGRTLEFLGKAGYADASLPPIKKAVK
WLKKHQEPNGSWYGRWGICYIYGTWAAVTGMAAVGVTLEDKSMKKGIDWLLSIQNEDGGW
GESCRSDMEKKYTPLKESTLTQTAWAVDALAAAGMADSTQARKGAAFLVREGKRKDWTAD
YPMGQGMANFFYIHYHSYRCIWPLLALSHYIEKSEAPD
>A0A537ZSW6|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MDGHRLAGDDGERGPVRPHRCASVVRCDNSGGCVTVVQELTALDRTLERGVHRLLSMQHP
DGWWKGELESNVTMTAQHLFWHHVLGLRTRELDRKIANELLARQRDDGTWAIWFEGPGDL
DTTIEAYVALELAGVDPGPLARDFIRRSGGIPRARIFTKCFLALLGQWPWQRIVPIPPEV
VLLPASGPVSVYDFACWARGTFVPLAVTAALRPVRGADIDLRAIGARPGESRPAPRPWGR
RREAIAFGERWVRARQEADGSWGGIQPPWVWAILMLASLGHGFEDETLRRAVEGWEGFTI
DEGDRLRPEACQSPVWDTALAVLALRAAGVSAEHPQLQAAGRWLLAEEVRDPRGDWAIRL
PELEPGGWAFEFENDLYPDVDDTVVVALALRELGIGDEAVRRGFAWTVGMQSRDGGWGAF
DVDNDAMWLYRIPFCDFGKVTDEPSADVTAHALEALGPEGGYDAAVAAGLEWLLAEQEPD
GSWFGRWGVNHLYGTGAALPALEACGLPSDHPAYRSAVRWLDSVQQPSGAFGEDIRSYFD
PSSRGRGAPTPSQTAWALLAYVAAGEHERLSTRRAADYLSRIQRPDGDWDEQHFTGTGFP
LDFMIRYHLYRLAFPLLALGRLRERLNA
>A0A538EUV1|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MTVAPERIETRLDEAIEAATNRLLELQHPGGWWVGELESNATMIAQHLFWHHVLGLRTPE
LDRKIANELLARQRDDGTWSIWFDGPPDLSTSVEAYAALKLAGVDPGPEARDYIRSQGGI
RKTRIFTKCFLALIGQWPWQRVTPIPVELVLLPPGGPVSIYDFSCWARGTFVPLSVCRAL
RPVRHADVELREIGARPGRTKGPPTPSRLRRIAIKEAERWVRAHQEADGSWGGIQPPWVW
SILMLAALGHGFEDETVRRAVEGWEGFTIDEGDRLRPEACQSPIWDTGLAVLALRDSGLG
PEHPALVRAADWLIGEEVTVKGDWSVRRPDLAPGGWAFEFENDLYPDVDDAAVVALALRR
CHRGHGAVDRGLAWTAGMQSRSGGWGAFDVDNEAFWLYKLPFCDFGKVTDEPSADVTAHA
LEALAPERGYGDSVRRGLDWLLAEQEDDGSWFGRWGVNHVYGTGAALPGLEACGIEPAHP
AFRRAVAWLDSVQNEDGGFGEDIRSYADPAWRGRGVSTPSQTAWALLAYVAASEADSQAA
HRAAEWLCSAQRPNGDWDEQQYTGTGFPLDFMISYHLYRLHFPLLALGRLRERLNR
>A0A537TWY4|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
PGRACHEIDLGPVERPRSFWDLADRLVARYGAQRLRPGRERALAYAERWITDRQELDGSW
GGIQPPWVWSLIALACRGHGPESPYFSRGLKGWGRFLVEDGDRLRPEACQSPVWDTGLAL
MALRAAGVAAEEPALERAGRWLLREEVRTRGDWALRLPGVEPGGWAFEYDNDLYPDVDDA
AVIAIALNELGLGRAAVDRSCRWLAAMQSRSGGWGAFDVDSDSYWLYEIPFFDFGAVIDP
PSVDVTGHAVELLAREPGYEDVVRRGVDYLVREQEDDGSWFGRWGVNYVYGTGAALPALE
AAGFAADHPVIRCAVRWLESVQNADGGFGEDCRSYDAGEDGLGWRGRGVSTPSQTAWALL
GLVAAGEVGSEAARRAAAWLCDAQRDDGDWDEEHFTGTGFPRDFLIRYHLYRIVWPVLAL
GRLRKALP
>A0A5B0FBS4|squalene-hopene cyclase|EC 5.4.99.17|Pseudomonas sp. ANT_J12|TrEMBL
MNTRVKDVLDNALSALLGKQQADGHWVFEFEADAGITSEYVLLMHFLGESLEPTLQTRLA
RYLRDRQQAEGGWSLLQGGRFNLNASVKTYFALKLLGHTKDEPHMQRASTLIRQHGGAAN
CNVVTRIWLALYNVIPWRVLPLIPVEVMLLPRWFPFHLSKIFCIPRLFTVAVSVLQVLRP
TARNPQDVGITELFIHPANETTPFPRAPHQNRVWFVCFSAIDRLLHRIDPWRPKGRRKKA
LDTAVAYVTGQLNGEDGYGATLPTIAISLIMLQALGYPRDHRAMQTARRACEKLLVVTEQ
QAYCQPCVSPVWDTAWACQALLETGNRRGWEAAVRGIDWLKQRQILDVYGGWAVTRPHLR
PGGWAFQYVLPNHPDVDDAALVATVMHKAMQVVPGADYGESIARAQEWIKGMQGRHGGWG
AYEADNTQYYLNSIPFAEHGMMIDHPTADVSGRCLALLGQLGATPVCDDITGKALNYLLA
EQETDGSWYGRWGINFIYGTWSVLEGLAAMGYDTQSSAVQKARHWLILRQNEDGGWGEDA
CGYSLDHPRHQPSVSTPSQTAWALLGLMAAGAVEHPVTAKGIEYLLKAQKNEGTWTDPHA
TGTGVPRVLYTTYHGYGLYFPMWALARYCTLRQARTPATEVI
>A0A5N9GE76|squalene-hopene cyclase|EC 5.4.99.17|SAR202 cluster bacterium|TrEMBL
MVRRARLCGRKEPKSGDATTVAQLKHSDVNQAADEAVQRSQDYFRRTQYPEGYWWGELES
NPTMEAEYLMLCHFTGRHDQERWRKICNYILSKQRSDGSWSQYYEAPGDVSTSVECYFAL
KLAGHSPDTEPLRKAREFILSKGGIPKVRVFTKIWLALFGQWDWKGTPNMPPEMIFLPSW
APFNIYEFASWARATVVPMLIILTRQPYCAVPESADIGELYPGGREGTDYHLPKPTGGFG
WSKALYWADKLVGLYQRLPVHPFRGRAERKIIQWVLDHQEADGSWAGIQPPWVYSLITLH
TLGYGPDHEAVKKGFQGFERFALEDEDKCNVQACISPVWDTCIAQLALLESGIDPEDPMV
QSSARWLMDKQIYATADWQVRAKGTRPGGWSFEFDNLIYPDVDDASIVVMALDQVRLPEA
EEPRRADSIQRGVEWMAGMQSKNGGWAAFDKDNNKKYLTKIPFSDFGETLDPPSVDVTAH
LLEMYGRLGYTKENRAVDRGFAYVVSEQEEDGSWFGRWGVNYVYGIGAVLPALEAIGEDM
SQAYIRLAVDWTVAHQNQDGGWGESCGSYVDPNLHGVGPSTASQTAWALLGLVAAGEHES
EAAQRGLVYLAETQLEDGTWDEPYFTGTGFPGYGVGERLKAMPDIGETSYQGLDMPAGFM
INYHLYRNYWPLLALGRYSQAVSGRL
>A0A800MP66|squalene-hopene cyclase|EC 5.4.99.17|Methylococcaceae bacterium|TrEMBL
MYTESFNEKNDLEAISVSAKKAFNLDFAINAAQAELTNLQNDEGYWHFELEADCSITADY
ILMMHYFGEENDSLQEQMATYLRARQTENGSYSLFTGGTDDLSCSVKVYFALKLAGDKTT
SPHMVKLKNYILAQGGAAKSNVFTRITLAIFEQIPWRGVPYIPVEIMLLPKWFPFHLDRV
SYWSRTVMVPLFILCTLKAKALNPKKINISELFVTPPDEEKHYFSNDTLLSKIFLGLDKL
GLITRPFIPKRLTQLSFDLALAWILERLNGEDGLGGIFPAMVAAYQAMLLLDMPLDHPDV
KTAREAVDKLIVFRDQEAYCQPCLSPVWDTGLAALALQEADPKGTRQSREKAYNWLKTKQ
LDKQPGDWQIRQPHLEGGGWAFQFENPHYPDVDDTAVVAFAMANADLPNLNESINRATRW
TAGMQSKNGGFGAFDCDNTDYYLNHIPFADHGALLDPPTADVSARCAMLLGHQIKNHPEY
QTTLDDTIAYIRSEQETDGSWFGRWGTNYVYGTWSVLLGLEQTQVPRNDPMYTKAVKWLK
SVQNSDGGWGEDNHSYHDDSTRGQAKSSTCFQTAWALLGLMAAGEVNSPEVKNGINYILA
NQTEKGLWVDPGFTAPGFPKVFYLKYYGYDKFFPLWALARYRNELIKL
>A0A4Y8MF95|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. ICN441|TrEMBL
MTATTDGSGGAPALRSPSASDHTTDHRPAPGDSAGLCTTALLTAQRSVEHLLGRQAPQGW
WKADLETNVTMDAEDLLLRQFLGVHDEKTTAAAAVFIRGEQREDGTWATFYGGPGELSTT
IEAYVALRLAGDRPDDPHMERAAAWIRARGGIAASRVFTRIWLALFGWWKWEDLPELPPE
LIYLPSWFPLNIYDFGCWARQTIVPLTVVSATRPVRPAPFALDELHTDRHRPNPPRPLAP
AGSWDGVFQRLDRLLHGYRAVALRPLRRAAMNRAARWIIERQENDGCWGGIQPPAVYSLI
ALHLLGYDLDHPVMRAGLESLDRFAVWREGTAGPGDRREGPARMVEACQSPVWDTCLTVV
ALSDAGVPADHPALVRAADWMLGEQITRPGDWAVRRPRLAPGGWAFEFHNDNYPDIDDTA
EVVLALRRVKHPDPARVEEAVARAGNWTMGMQSKCGAWGAFDADNTGTFPNRLPFCDFGE
VVDPPSADVTAHVVEMLAQEGRAHHPRTRRGVDWLLREQEPHGAWFGRWGVNHLYGTGAV
VPALTAAGVPVSHPAIRRAVGWLESVQNDDGGWGEDLRSYREESWIGRGVSTPSQTGWAL
LALLAAGERDGSAVERGIAFLAATQREDGSWDERYFTGTGFPWDFSINYHIYRQVFPLMA
LGRYVHGQPPAGRNGD
>A0A6P0LE61|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO3H5|TrEMBL
MQTQDRIVESGVTEAIANSQSYLLAQQYPDGYWWAELESNVTITAEMILLHKIWGTDKQR
PLHKAEAYLRSQQRKHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDSALVRARDFILR
RGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPEWFPFTIYEMSSWARGSTVPLLI
VFDQKPVFDIHPRINLDELYTEGADHAKFELPRNSDWTDLFVLLDDGFKLAEDLNLVPFR
KEGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPVVQRGLEAIDRFAIE
TPDSYRVQACVSPVWDTAWVLRAMVESGLEPDHPALVRGGEWLLQQQILDYGDWVVKNPQ
GKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLKQAAIARGLAWIASMQCNQGGW
AAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEMLGSCNLSIESQPLEKAIGVREA
WPLASAAPKAIAFLIQEQEADGSWFGRWGVNYIYGTSSALSALSKIAPHTHQRSIERGAA
WLVKCQNLNGGWGETCLSYDDPSLKGLGISTASQTAWALIGLMAAGEATGNWAMDAIEKG
VNYLVSTQQPDGSWDETEFTGTGFPSHFYLKYHFYQQYFPLLALGRYQMSVAS
>A0A6L9YRL7|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO3E8|TrEMBL
MQTQDRIVESGVTEAIANSQSYLLAQQYPDGYWWAELESNVTITAEIILLHKIWGTDKQR
PLHKAEAYLRSQQRKHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDSALVRARDFILR
RGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPEWFPFTIYEMSSWARGSTVPLLI
VFDQKPVFDIQPRINLDELYTEGADHAKFELPRNSDWTDLFVLLDDGFKLAEDLNLVPFR
KQGLEAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPIVQRGLEAIDRFAIE
TPDSYRVQACVSPVWDTAWVLRAMVESGLDPDHPALVRGGEWLLQQQILDYGDWVVKNPQ
GKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLKRAAMARGLAWIASMQCNQGGW
AAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEMLGSCNLSIESQQLEKAIAFLIQ
EQEADGSWFGRWGVNYIYGTSSALSALSKIAPHTHQRSIERGAAWLVKCQNLNGGWGETC
LSYDDPSLKGLGISTASQTAWALIGLMAAGEATGNWAMDAIEKGVNYLVSTQQPDGSWDE
TEFTGTGFPSHFYLKYHFYQQYFPLLALGRYQMSVSS
>A0A534H5A1|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MSRKAGTSAALAGTEGLLRADAPARKLPGEKLSPLESAIAAARDELIQLQRPDGSWELEL
EADCTIPAEYIMMMHFLGELDSALEAKLAAYLRQRQAGYGGWPLYHGGAFDMSCSVKVYF
ALKLAGDDPESPHMARARAAILERGGAAACNVFTRIALALFGQLPWRGVPYIPVEIVLLP
RWFPFNIHRVSYWSRTVMVPLLILCTLKPRAKNPRNVDIRELFTTPPGQERRYFRRPLGG
SATLARAFFCLDRLARSLDGLIPRALREHALERAEAWMLERLNGEEGLGAIFPAMVNALE
ALAVRGYSPDHPHRRGAKRALEKLLVEDYSSAYCRPCVSTVWDTALASLAMQEEGSAGAR
AAALRGLEWLEPRQLLDEPGDWRTRRPHLPGGGWAFQRANSYYPDLDDTAAVAWSMHRST
DPGRFSFALSRALDWLVGMQSENGGFASFDVDNTSYYLNEIPFADHGALLDPPTSDVTAR
VVTALARVGRPEDRGALTRAIDYLRREQEANGSWFGRWGTNYVYGTWSVLCAFAAAGIGP
DDPAVQRAVSWLESRQNPDGGWGESNDSYEPGRAGASAPSTPYQSAWAVLALIAAREAGS
DAVRRGIEYLLRTQRPDGLWSDPSFTAPGFPRVFYLRYHGYCAYFPLWALAAYRNSTAAG
PGTVH
>A0A4U0F991|squalene-hopene cyclase|EC 5.4.99.17|Cohnella pontilimi|TrEMBL
MYSLRCFCGTGGRSAGILDTVKGIKWIVDTLRKDQSADGSWAYPFETGISTDAYMIILLR
TLEIDDEELIEGLCQRILSKQQKNGAWKLFYDEGEGNVTATLEAYYGLLFSGFYSEEDER
LRAAKKFILDHGGLSEVSTFTKIMLALTGQFKWPSVALMPIEMILLPHNFPINFYSFSVF
GRANMTPIMILADKKFSIPSPYAPDLSDLKLKRDDEDQWVGSREWRSLRSYIQDGVKRLL
GIPRVLHRLAIERAEKYMLDHLEQDGTFYSYYSSTFLMIFALLSLGYKKSDSVIIKAVDG
IRAMKSVINGFPHMQYTTANVWNTSLIGYTLQAAGVSHEDPMVMKANKYLLSRQHTRFGD
WVVHNPNSLPGGWGFSDVNTMNPDVDDTTASLRSISNIASRDPSAWKRGVDWLLSMQNDN
GGWPAFEKNTDSKLLAFLPLEKGRFMLMDPTCADLTGRTLEFFGNYTNLPNIPNSPVIRN
AVNWLLRNQRKDGSWYGRWGICFIYGTWGAITGLRAVGLSKSHPSIQKASAWLSSIQNPD
GGWGESCRSDIQMTYVPLTTSTLTDTAWALDALIAIADRPTTAIQKGITYLLGSLEIEDW
TTDYPKGQGMGGAFYIHYHSYRYIFPLLTLAHYRRKFE
>A0A5C8VJ39|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium sp. WL7|TrEMBL
MREAVSKVEPLQRSKTQGISLDDVERGVAQATRALINLAHDDGHICFELEADATIPSEYV
LFHHFRGTPVPEGLEAKIGNYLRRTQGRHGGWALVHEGPFDMSCTVKAYFALKMIGEDIE
APYMRRAREAILSRGGAANANVFTRFMLALYGEVPWRAVPVMPVEVMFLPKWFPFHLDKI
SYWARTTVVPLFVLQATKPRARNPRGISVQELFITPPESVRTWPGSPHATWPWTPIFGFI
DRMLQLVEDRLPRKSRQRAMEKARAWVSERLNGEDGLGAIFPAMVNSVLMYEVMGYRPDH
PQVRVACDAIEKLVVEKADEAYVQPCVSPVWDTALAAHALLEAGSPEAEAQARAGLDWLK
PRQVLDIVGDWAARKPKVRPGGWAFQYANAHYPDLDDTAVVVMAMDRAMHQHGLVAGMPD
YKASIARAREWVEGLQSQDGGWAAFDADNNHMYLNHIPFSDHGALLDPPTADVTARVVGM
LAQLGETRETSRALDRGVNYLLNDQEEDGSWYGRWGMNFIYGTWSVLCALNAAGVDSADP
RIQRSVSWLIRIQNPDGGWGEDASSYKIDPAFEAGSSTASQTAWALLALMAAGAVDDPAV
TRGINFLTRTQGADGFWNEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKRTNSRR
VQFGM
>A0A2S1TZ41|squalene-hopene cyclase|EC 5.4.99.17|Piromyces sp|TrEMBL
MLSKKLGALTVTAAIPVLILSFFLAQIDIQRYNIGAAIDVLTKKPLPKEVPNPPSSKEFL
VRLSPVIDKATFTEEDVSRTMQKAVDNILKGFKKDEYFEFNSYLGPNFVAAYYVVQKFLQ
HKGTEFDPHTKLDEKVLYKLLSTTQYPDGSWANVVDGSVNFGDIDTTVYNYWALKVMGEP
LDSPMMANARRFILSKGGLRHTNCLSRYWQTFFGNIKWSENIYIPLFIFGDGIFGRLLNF
EGRVAQWVYPHVLPITYSTYHQVQKDMGSRFDLLELLPENADKPLNDPIYAERPAAKRNI
AQKGEAEEAVIKVIKRMFRNQQPNGSFGGYTVSTLFGIIAYDDFMNRYPESQYIPEIKER
IKKGYKFIEMMYFDNEAEYMGNLCNGRSWETILSGIALVEAGYEGAEVVKAANYLAKKQR
DNGGIPYGVDFEYASDFDDTAETVILWSTFKGNKELEKRIDHANQLLFEIQNNDGGFAAF
DRERQGFKPIEFVTSAFSDAAEIWDPSCADVTGHVLEGFGESGYNYTNPVVKKGIEYLIN
TQKPNGGWEARWGNNYIYSFGAVIPGLKKVGYDLNQPWIRKAVSWVLQHQNLDGGFGESP
LSYKSEKWCGVGISTPSQTAWALLGLLEIKRADVMDVGDSVERAIQFLINEMDREGKWED
KSVVGTGHRGFLMMMYLTYPHTWPLMAMSRYQRYFGVGEVELKHSEVISDLPTNIIEKIT
STAAEAVKPSN
>A0A6N8Y069|squalene-hopene cyclase|EC 5.4.99.17|Holophagales bacterium|TrEMBL
MIDAAVRNLLGQRRDDGHWCAELEGDTILESEYVLLLHFLGRGDDPRVAACCERLRGQQQ
QDGGWAIYPDGPTDPSVSVKAYLCLKLAGDDPQSPRMADARRAILRAGGLRACNSYTRLY
LSIFGLWTWRRSPAVPPELILLPRWFYFNLHEMSSWTRTIVVPLSVIWALKPSVPLDVTL
DELQGDSRPGRKRATLYESFWSFVFAGVNGLIKLVEVIGPVPGWRRPALKKAEEWLIAHV
EGSDGLGAIFPAMVNAVIAFRCLGYEESHPLVQGQLRELERFEIEEAGEMRLQPCLSPVW
DTALSVGALLAADMDGNDAPIQEAVEWLLEREITVAGDWREKSLQGASGGWCFEYRNDHY
PDCDDTAEVLLVLAAVRDRAGELEARKQAAAARGKRWLLGLQNPDGGWASFDRCCDKEVL
TLIPFADHNAMIDPSTPDITARVISALLAHGHDPGDGPVRRATDYLLREQEKDGSWPGRW
GANGIYGTWLALSALAPLATRTGGRPEGRLSRACRLGWRWLLAAQNEDGGWGESLRSYDD
PGFRGRGRSTASQTAWAMMGLIASLESRFWSDDAARTVTALDRAVAFLQERQRDDGSWYD
RDWTGVGFPGVFYLRYHGYAQYFPLEALAAYRRLAVPEPDAMPANGPF
>A0A6B2R8A1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID10362|TrEMBL
MTATTDGSTGAALRPLAASASDTDSTIPAAAAGVPEAAARATRRATDFLLSKQDAQGWWK
GDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDSPDAPHMARASEWIRSRGGIAASRVFTRIWLALFGWWKWDDLPELPPELI
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFSLDELHTDPARPNPPRPLAPAA
SWDGAFQRIDKALHAYRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPEDHP
QLVKASDWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHH
DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAVEGLAHDPRTRRGIQWLLDAQEADGSWFGRWGVNYVYGTGSVIPALTAAGLPTS
HPAIRRAVRWLESVQNEDGGWGEDLRSYRYVREWSGRGASTASQTGWALMALLAAGERES
KAVERGVAWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFA
KKSPAAEAPTASVVAEVKGS
>A0A8I0UEA1|squalene-hopene cyclase|EC 5.4.99.17|Gluconobacter japonicus|TrEMBL
MLIYPDEKEDRMSETLSHKPIEGDDVTRAIEGAHAALGKRQKDDGHWVFELEADATIPAE
YVLLEHYLDRIDQEKQNKIGVYLRRIQGEHGGWPLYFGGGFDLSATVKAYFALKAIGDSI
DAPHMRRAREAILDHGGAARSNVFTRIQLALFGEVPWDATPVMPVELMLLPRKAFFSVWN
MSYWSRAVLAPMLAVGALKPQAVNPRGIHIQELFVKPPSEVKDWIRGPYRSIWGRAFKHL
DTALRPVLPLIPKTVHDKALKAAISFIEPRLSRGGLGAIYPAMANVVMLYRALGVPDSDP
RVVTAWESIQDLLVHKDDEIYCQPCVSPVWDTGLSGLAMMEAASGAHPTKRDETLAKLKK
SAEWLRDRQILDVKGDWAINTPDLRPGGWAFQYENDYYPDVDDTAVVGMLLHRVDPEENR
ETIERAREWIIGMQSTNGGWGAFDVDNDLEVLNHIPFSDHGALLDPPTADVSARCISFLC
QLGHPEDRPVIDKALDYLRKEQEKEGCWFGRWGTNYIYGTWSVLCALNIAGISYDDPMVK
RAVNWLEDIQRSDGGWGEDCATYEGAPPGIYKESLPSQTAWAVLGLMAVGRRDSEAVKRG
INFLMSQQDENGEWQEEAYNAVGFPKVFYLRYHGYKQFFPLQALSRYRNLGTSNTGRVEY
GF
>A0A6I5N3A4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces rochei|TrEMBL
MTATTDGSTGATLRPLAAAASENEITTPDTAAGVPEAAARATRRATDFLLSRQDAQGWWK
GDLETNVTMDAEDLLLRQFLGILDEETTRAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDAPDAPHMARASEWIRSRGGIAASRVFTRIWLALFGWWKWDDLPELPPEII
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAVPNPPRPLAPAA
SWDGAFQRIDKALHAYRRIAPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHP
QLVKAADWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHH
DPERVEQAIGRGVRWNLGMQSKNGAWGAFDVDNTSSFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAVEGLTHDPRTRRGIQWLLAEQEADGSWFGRWGVNYVYGTGSVVPALIAAGVPAS
HPAVRRAVAWLESVQNDDGGWGEDLRSYRYVREWSGRGASTASQTAWALMALLAAGERES
KAVERGIAWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFA
QKSGAARPATETSTAEVKGS
>A0A6M1RH92|squalene-hopene cyclase|EC 5.4.99.17|Limisphaera ngatamarikiensis|TrEMBL
MTQRSRNAVSEVPLSSVQAGPGSSWLDRLHEAIQRSQAFWLGQQKPEGYWIGELIVDVTL
VADMVAFHHWDRSVDPAWQRKAVRHIFDKQLPDGGWNIYHGGPAEVNATIKAYLALKLAG
IPPTHPRMLKAREVARSLGGVPRMNTFSKLYLALLGLFPWKYVPTIPCEVLLLGKWFRVN
FWDMSNWTRAMLVPLAIINHFRPTRPCGVDLDELYPEGFHERDLRLPRDPDWFTWRNFFL
LLDKVHKFAELWVRLGIHPFRRRALRKAEQWMLERFEGSDGLGAIFPAMLNSLIALKALG
YPDDHPEVIRARRHLKELEHETADSVRIEPCLSPVWDTAIVTIALRESGIPEDHPAVVRA
VDWLLDREIRFRGDWQHKNPAPVEPSGWAFEFNNKWNPDVDDTAMVLLALRQVPTRDPAR
RDAAFRRGLNWMLTFQCRDGGWAAFDKDCTNNILEKVPFADHNAMLDPECADITARVLEV
MGREGYSLDHPQVRRAVAWLRSQQEADGSWYGRWGVNYIYGTWQVLRGLHALKMDMNQPW
LLRARDWLESVQHEDGGWGERCNTYDDPVFKGQGPSTASQTAWAVMALCTFGDPHRPSLR
AGVEYLLRTQNLDGTWTEEETTGTGFPKVFYLKYDSYRNAWPLLALATYRKLLRGEY
>A0A7W1WSD5|squalene-hopene cyclase|EC 5.4.99.17|Paenactinomyces guangxiensis|TrEMBL
MKYLYIEQVDQVIADLTQFLTKSQKTDGRWSFCFESGTMTDAYMILLMKLLGRSDSRFTG
SLLQRILGKQTRDGTWKLFQDEKEGNLSATIDSSLALLYAGVRDRRDPLMRKAREFILEQ
GGTGQAGSLTKVILCLLGHLDWFYLPKIPVEIFLLPSWFPVHFFDFVGYTRVHVAPILLA
ADREFSVKLPGKSAVSEWLPPVKKPGYPDNRDHIWTKEEIRAAFAHVSLSGKELHTRAVQ
WGERFMLERIEPDGTLYSYFSSTFLMIVALLALGYKKNHPVIQKAMKGLYSFVWKSGQKA
HLQETTSSVWDTSLILYALQEAGMKPDHPVVRRGLRYLLQRQHTRSGDWVIRNPGVLPGG
WGFSDVNTMNPDVDDTAACLRALAPSVRQVRHKIPWDRGLSWLLSMQNKDGGWPAFERNT
DKAWLKLLPFKDGRPVWGDPSTADLTGRTLEFLGREMRWTINHPIVRRGWNWLYRHQRPD
GSWFGRWGISGIYGTWAALTGMAAVRVPRNHPVVRKGIQWLLSIQNRDGGWGESCYSDLR
KRYVPLRASTPSQTAWALDALISFHDKPTPAIQSGVKCLLSLLEKESWESSYPTGAGLPG
QFYIHYHSYRYIWPLLTLVHYRKKYKSG
>A0A7X7K1M4|squalene-hopene cyclase|EC 5.4.99.17|Anaerolineales bacterium|TrEMBL
MREVLNGSGARSAVTSGSEPGAVATDTHALQRAIERTCGYLLTAQRPSGFWQGELEADIS
VTAGYVSFMRYFGFEIGERAKQVQSLLLCEQLPDGGWSAYAGGGGHLDVSVQVYLALKLL
GCSADEPFMHRARDFIVAQGGIERCATFTRILLALFGQVDWETLPMVPPEIMLLPRFSPI
TIYDFSSWARATIVALTIVFTHRPVYPLPPEEGVRELYALPSHSRRQHWGPRPKPGPFTW
GRAFVIADRLLKACERRRRHPGRQRALREAERWVLAHQDTDGSWGGIMLPWLYSLVALGC
LGYSNDHPVMAKGLAGLEQFIITDGPHMRLEPAVSPVWDTAYVLLALREAGLPADHPALT
RGAEWLLDRQILTKGDWQVKRPHAVPGGWAFELVNDQYPDIDDTALVPITLQGLRLPDEE
RKQAACERAIAWLLAMQSRNGGWAAFDVDNDKRILAHIPFADFVTPLDPSSVDVTAHVVE
LLARMGADPARPALQRALRFLYSQQEPDGAWFGRWGVNYIYGTAAVLMALRAAGEDMRSE
PMQRATHWLAAHQNLDGGWGETCDSYEAGGPRGHGSSTASQTAWALLGLLACRLEHDPIV
RRGIDYLISTQSADGRWDEAAFTGTGFPRAFYLRYHMYPIHFPLIALARYARGIDSTTGE
DGDGGM
>A0A7X4AHZ7|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
MDASGLDVCIDRSVKHLLSLQAEDGYWWAELESNATMAAEHLLLERFLGTTEEEREQGIV
RYLLGLQTEDGSWPVYWGGPGDVSITTEAYFALKLAGVDPERDEMKRAREFIRDKGGVGA
TRIFTKLWLALFGQFEWSALPAMPPESILMPVSSPLNIYMFASWARATIVAILVVWAYRP
VVPIPEYAHVDELYLDPMDRRSIPLRRDRQPFTWRNAFLAIDRVLHAHERLPWKPLRQYA
LKECERWIIEHQEADGTWGVIQPPSVYSLIALRAHGYSMDDPVMKKGLNGFLGDFALRRG
NTFSVQPCLSPVWDTALAVTGLREAGVPADDEALVQAGRWMLAHEVQSLGDWALTVPGIE
PGGFPFEFSNELYPDTDDTAEVLIALRLVDVRGKDGPFHRAKRWLRAMQSTNGGWGAFDR
DNNDEFVSRIPFADFGATFDPPTEDVTAHIVEAFALEGTPPSDEMIEQALGYLWDTQEPD
GSWWGRWGVNYLYGLGAAVPALVAAGVDPADPRLQRAVRWLEHHQQPDGGWGESCATYED
PSLRGQGPSTASQTAWALLALLALEPPDHPAIVRGIDYLVRTQTDEGEWHEPHFTGTGFP
RDFMLKYHLYCNYWPLWALGRYRRLRDGNPIHLPDTDPLA
>A0A6L7MLD9|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
MTTRETPESSVSPGLLNAVSKAVSRSQDYFARTQSPEGFWWGELESNSTMEAEYLMLTHF
LGIGDEDTWRKLTNHLLETQREDGTWGQYYGSPGDLSTSVECYFALKLAGLSMDDPRMIK
AREFILSKGGVPQARVFTKIWLALFGQWDWKRVPAIPPEMALLPSWVPMNLYDFSSWARA
TMLPLSIVMTHRPSCRIPDSAAISELFPNEQGKSPRPGSMEGVAGIFHIADRIFRWYNSF
PLHPVRRIAIRRAVKWIVDHQDEDGSWGGIQPPWVYSLISLKVLGYDLNHPVMRKGIEGF
RAFTIEENGAMRVQACVSPVWDTCLAMVALEDSGLPPDSPILSRAGEWLIRAQVADGGDW
QVRVKNTTPGGWAFEFANSAYPDIDDTAEALIALKSVDTEDPERHRKAIRRGAEWMLGMQ
SKNGGWAAFDKDNTRRAVAAIPFADFGEMIDPPSADVTAHVVEALVRVGYQADMAPLRKA
ARYLWNEQEEDGPWFGRWGVNYIYGTGAVLPALKAMGEDMSAGAVRRAVAWLVAHQNEDG
GWGESCASYADLALAGHGPSSASQTSWALLALLASGESDSHAVRRGIEYLVATQREDGTW
EEPWFTGAGFPGYGVGSRSKRARSQGMELPSGFMIKYHLYRNYWPLMALGRFRRCSERCP
NRGCLIQ
>A0A1Q8LWS8|squalene-hopene cyclase|EC 5.4.99.17|Pseudonocardia sp. Ae717_Ps2|TrEMBL
MTPAHAGTGRLADEVAEAIAGGAEALLRSRRDDGVFDYGADSLRSTLATAGAVTALHFAD
PGGTADLIAAGAARLRRTQTEDGGWAMVPGLPAEPGPTAVSAAALHLVDPAGSAEQVAAG
RRWMERYGGLAAIPHPEVVLWCRQFYGFVGWIAPADMRRFPLELALLPGLYRRLFDLRLP
MASALGLAQTRHRRMTRVQRTLSRLAEPNALRVIRQTYEHEGSAGSWSEDAWVTGLVCTG
LARAGVGQDMVDAAVGWLRRSMHPDGSWATTPLDAAWTMYAVRGLVEAGYGDDERLVASR
DALLGLQQHRPFLAFGCPPGFWGWTAGRGWPAVLETGEIVSVLSRLPGTVQGAAVAEGVG
WLTDRQDSRGSWGLCVRNTRVANSGPCPTTTAQALDALLDAGVPADDRRVRRALRWLGRA
QLTGGGFESVWYREHTMGTAAVLETFARCGRGGDGPAVRARALLERTRNPDGSWGDGHGA
PGTVEETGWAVAALLAAGAAPAEVEPAVRWLLAARLPDGGWPAAPVHEYVRRVSRYANPG
FTHGMALRALGRYRKALT
>A0A846DGN9|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO2B7|TrEMBL
MQLQESRVQTPPTLSQVIKASQDYLLSIQDPQGYWWAELESNVTITAEVVLLHKIWQTDE
IRPLDKVETYLRQQQKDHGGWELFSGDGGDLSTSVEAYMALRLLDVPATDPALIKARDFI
LKKGGISKSRIFTKMHLVLIGCYDWRGVPSIPPWIMLLPEDFPFTIYEMSSWARSSTVPL
LIVFDKKPVFSVNPSITLDELYAEGVENVKYEMPRNGDWTDIFVLLDNAFKLAENLNFVP
LRQKSLKCAEKWVLERQEATGDWGGIIPAMLNSLLALRTLNYDTADPIVERGLKAIDNFA
LETEDQYWIQPCISPVWDTAWALRSLVASGLAPNHPALVKGGEWLIDKQILDYGDWTVKN
KEGKPGAWAFEFDNRFYPDLDDSAVVIMALNGVKLPNETLKQAAINRCVEWMATMQCKPG
GWAAFDLDNDQDWLNLLPYADLKAMIDPNTADVTARVLEMLGECNLSMDGDRVERAIAYL
SKEQEADGSWFGRWGVNYIYGTSGVLSALAVLQPKYERPGSTLLKTMMREGAAWLIQCQN
SDGGWGETCRSYNDPSLKGKGVSTASQTAWALIGLIAVREFTAKPIDQVLERGVNYLVST
QHSDGKWNESEFTGTGFPCHFYLKYHLYQQYFPLLALASYQTYFGN
>D6V590|squalene-hopene cyclase|EC 5.4.99.17|Afipia sp. 1NLS2|TrEMBL
MTDIATMVAPERQRLDDGIASASRALLDVQKPDRHWVFELEADVTIPAEYILMRHYFAEP
VDTVLEGKIAKYLRRMQNDNGGWSLFYGHEFDMSASVKAYYALKMAGDSPDAPHMKKARE
TMLARGGAVKANVFTRIMLALFGQLEWKAVPVMPVEIMLLPRWFPFHLTKISYWARTVIV
PLLVLMTLKPRARNPLGIGVRELFIEDPKTIGPTPKAAHQSQVWFTSFDIIDRVLRLADP
FFPKAMRQRAIRKAEEFVTERLNGVDGLGAIFPAMVNSVMMYDVLGYTPDDPNRALARES
VERLLVIKDDEAYCQPCVSPVWDTALAAHAMIESGQAADLEAAKASLDWLLPRQVLDVKG
DWADKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRVRRMDGTTKYDDAIARAKEWIL
GLQSVDGGWAAFDADNLEYYLNNIPFADHGALLDPPTDDVTARCLSMLAQLGDTLETSEP
MRRAVAYLRKTQLADGSWFGRWGINYIYGTWSALCALNAAGVPHDDPMIAKAADWLEAIQ
NADGGWGEDGNSYRLDYKGYERYATTASQTAWATLALMAAGRVDRPATKNGIDNLMQSQG
VDGFWQEPDYTGGGFPRVFYLRYHGYSKFFPLWAMARYRNLRSSNSRFVGAGM
>A0A6C1CAJ0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces albus|TrEMBL
MTATTDGSAGPGVSGTKNLTSDTLAPAAGGRESTVALAERTAARAVDHLLARQDEAGWWK
GDLDTNVTMDAEDLLLREFLGIRDEKTSAAAARWIRSQQREDGTWATFYGGPGELSTTIE
AYVALKLAGDDPEAPHMARAAAWIREQGGIVRSRVFTRIWLALFGWWRWEDLPEMPPEII
WFPKWFPLNIYDFGCWARQTIVPLTIVCAYRPVHPAPFRLDELHVDPARPNPPAAKAPLT
SWDGAFQRIDRALHAYRKVGSRRLRRAAVKEASRWIIERQENDGCWGGIQPPAVYSLIAL
RLLGYDLDHPVLKAGLESLDRFAVWHDEQTRMIEACQSPVWDTCLTAIALADAGLPRDHP
ALVKAADWMLGEQIVRPGDWSVRRPQLTPGGWAFEFHNDNYPDIDDTAEVALALRRIEHP
DSERVNRAIARAVRWNLGMQSRDGAWGAFDVDNTSKFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAAEGKQDDPRTRKAIAWLLSEQESNGSWFGRWGVNYLYGTGSVVPALVAAGLPTS
HPAIRRAVGWLESVQNDDGGWGEDLRSYIDSEWIANGTSTASQTGWALMALLAAGEQDSK
AVERGVTWLAETQREDGYWDEPYFTGTGFPWDFSINYHLYRMVFPLTALGRYLHGDGLAR
RTGRDA
>A0A5A8A474|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium sp. P1-11|TrEMBL
MREAVSKVEALQRSKTQGISLEDVERGVAQATRALTALAHDDGHICFELEADATIPSEYI
LFHHFRGTQVPGDLEAKIGNYLRRTQGRHGGWALVHEGPFDMSCTVKAYFALKMIGDDIE
APHMRRAREGILSRGGAANANVFTRFMLALYGEVPWRAVPVMPVEVMFLPKWFPFHLDKI
SYWARTTVVPLFVLQATKPRARNPRGISVQELFVTPPESVRSWPGSPHATWPWTPIFGFI
DRVLQRVENHMPRKRRQRAMEKARAWVSERLNGEDGLGAIFPAMVNSVLMYEVMGYRPDH
PQVRVACDAIEKLVVEKADEAYVQPCVSPVWDTALASHALLEAGGPEAEAQARAGLDWLK
PRQVLDIVGDWAARKPKVRPGGWAFQYANAHYPDLDDTAVVVMAMDRAMHQHGLVAGMPD
YKASIARAREWVEGLQSEDGGWAAFDADNNHMYLNHIPFSDHGALLDPPTADVTARVVGM
LAQLGETRETSRALDRGVNYLLNDQEEDGSWYGRWGMNFIYGTWSVLCALNAASVDSADP
RIQRAVNWLIRIQNPDGGWGEDASSYKIDPAFEAGSSTASQTAWALLALMAAGAVDDPAV
TRGINFLTRTQGADGFWKEERYTATGFPRVFYLRYHGYPKFFPLWAMARYRNLKRGNSRR
VQFGM
>A0A7W4YPV2|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus alkaliphilus|TrEMBL
MSLNETAFANAAPQVDSAPRQPAGPQQAPATRLSAPALDHGIDRALDTLLRQQRPDGHWV
YELEADATIPAEYVLMVHYLGEAPDLDLEARMARYLRRIQNPDGGWPLFHQGRSDVSASV
KAYFALKMAGDDPQSAPMQRARQAIHAMGGAEASNVFTRTLLALYGVLPWKAVPMMPVEI
MLLPRWFPFHLSKVSYWARTVIVPLLVLNSLRPQARNPRGVGINELFVGNCHTVGLPPRA
PHQHAGWYTVFRGLDALLRVAEPLFPRTLRRRAIAAAQRFVRERLNGEDGLGAIFPAMAN
SVMMFDVLGVPPDDPARAVARRSLERLLVEHGDEAYCQPCLSPVWDTALATHALLETGDA
RAAQAAGRALDWLRPLQVLDLRGDWAVRRPLVRPGGWAFQYANAYYPDVDDTAVVAAAMD
RFMRAHQAPGRYGEAVARATEWIVGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDPP
TADVSARCLSMLCQTGATPGKSEPAARALRYLLAEQMPDGSWFGRWGTNYIYGTWSALCA
LNAAGLPPAAPELQRAVAWLARIQNADGGWGEDGSSYRLDYRGYEPAPSVASQTAWALLA
LMAAGAAQHPAVARGIDYLLRTQQPGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWALA
RYRNLQRGQMGQSGQVSWGL
>A0A525IG71|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp|TrEMBL
MNRVDPTLAGLQSLEAVDRAVDRAGQAMRACQMSDGHWRFELEADATIPAEYVLLRHFRG
ETRDLDLERKIAAYLRRVQSEGGGWPLVHDGAFDLSASVKAYFALKTIGDDPEAAHMARA
RAAILEHGGAAKTNVFTRFLLALFEQVPWRAVPSMPVEIALLPRWFPFHLDKISYWARTV
LTPLLVLQALKPRPAVPGAIGVAELFVTPPEQVSEWPAGAHQHWAWVKVFGEIDRALRIA
EPQFPPATRKRAMDAAVAFVSERLNGEDGLGAIFPAMANAVLMFDALGYDKDEPRLAQAR
AALDKLLVIGEDEAYCQPCLSPVWDTALAAHALLEAGDAPSFAAVAKGLQWLEPLQVLDV
KGDWAASRPLARPGGWAFQYANPHYPDLDDTAVVVMAMDRFMRSGGGKDYAQSMARARLW
VEGLQSKGGGWAAFDADNTHHYLNNIPFADHGALLDPPSADVTARCVSMFAQLGETPERT
VTLKRGVDALLDFQEADGSWFGRWGMNYIYGTWSALSALGALEFDLRSAPVRRAVAWLLA
AQNDDGGWGERAESYRLDYRGFERASSTASQTAWALLALMAAGESDSLAVSRGIDHLVTT
QGEDGFWDEPFHTATGFPRVFYLRYHGYPKIFPFWALARFRNLRRSTPPISRLGM
>A0A841BIL2|squalene-hopene cyclase|EC 5.4.99.17|Allocatelliglobosispora scoriae|TrEMBL
MAAARDSVRRAVLARVAGDGAVRDPCHGRALETALLLSLMDRVGYTSPARDSLARFLDSR
RQPARLLSEQLLREVPDFTVDRKRATLCAFLVALGEPLPHGAPDPADLTLEGLHPWARVQ
ITAVKAILAAATGRPESITPDDHNRLLDTQQAEGVWEHNLLVHLSVLHGLAHRPDTTHVV
RAGIAKALDHQRHDGGIPFVSDVDTWCTATAGVALTAAQTDPAALHPLAEHLVGRQAADG
GWSFTDTVQLTDTDDVSVAVEFLHALDPHRYRNAISRGLAYLRGRQGPDGGFPTYAATPA
EACMTAAAANALLCAPQHHRTHLDQALGHLMRSQRDDGSFPADWSASRLHTPFRAVLAAT
QRETADDPRAVRIAAKVSGAILGTQNPDGGWGQRIGDASDAISTSYAVIALTRGPESDAA
ARGVEFLLGSLRDDGGIASVPDSIGPRPFTFTVPALADIFALLALGHVQSRIEGTARR
>A0A375CFQ6|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus taiwanensis|TrEMBL
MSTNETALANAAPQVDSAQREPAGPVQAPATRLPAPALDHGIGRALDALLHQQRPDGHWV
YELEADATIPAEYVLMVHYLGEEPDLDLEARMARYLRRIQNPDGGWPLFHQGRSDVSASV
KAYFALKMAGDDPQSAPMQRARRAIHAMGGAEASNVFTRTLLALYGVLPWKAVPMMPVEI
MLLPRWFPFHLSKVSYWARTVIVPLLVLNSLRPQARNPRGVGINELFVGNCHTVGLPPRA
VHQRAGWYTVFRGLDALLRVAEPLFPRALRRRAIAAAQRFVRERLNGEDGLGAIFPAMAN
SVMMFDVLGVPPDDPARALARRSLERLLVEHGDEAYCQPCLSPVWDTALATHALLETGEA
RAAQAAGRALDWLGPLQVLDLRGDWAVRRPLVRPGGWAFQYANAYYPDVDDTAVVAAAMD
RFMRAHHAPGRYGEAVARATEWIVGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDPP
TADVSARCLSMLCQTGATPGKSEPAARALRYLLAEQMPDGSWFGRWGTNYIYGTWSALCA
LNAAGLGPEAPELQRAVTWLARIQNADGGWGEDGSSYRLDYHGYEPAPSVASQTAWALLA
LMAAGAAQHPAVARGIDYLLRTQQPGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWALA
RYRNLQRGQSGQVSWGL
>A0A8J7AGN4|squalene-hopene cyclase|EC 5.4.99.17|aff. Roholtiella sp. LEGE 12411|TrEMBL
MQTQDSVKVNQVAAAIAASQKYLLSIQNPAGYWWAELESNVTITAEVVLLHKIWGTDQTR
PLDKVETYLRDQQRQHGGWELFYGDGGELSTSVEAYMALKLLGVSANDPAMIQARAFILK
RGGISKTRIFTKLYLALLGCYNWRGIPSLPPWVMLLPTAFPFNIYEMSSWARSSTVPLLI
VCDRKPVLITNPTINLDELYVEGVEQVHWELPRSGDWTDLFLTLDDGFKLAESLNLVPFR
EEGIKAAEKWILERQEATGDWGGIIPAMLNSMLALRCLDYDVSDPIVERGLQAIDNFALE
TEDNYRVQPCISPVWDTAWVMRALVESGFAPDDPAVVQAGQWLLQKQILDYGDWALKNHQ
GKPGAWAFEFDNNFYPDVDDSAVVVMALHVAKLPNEKLKQTAIARGLNWIASMQCKPGGW
AAFDLDNDQDWLNSIPYGDLKAMIDPNTADVTARVLEMLGACDLSIDMHNLERALTYLLD
EQETEGCWFGRWGVNYIYGTSGALSALALIDPQRHQFSIKRGEAWLVVCQNPDGGWGETC
RSYNDPSLKGQGDSTASQTAWALIGLIAAGEATGKLALDTIERGINYLLATQQPDGTWYE
ANFTGTGFPGHFYLKYHLYQQYFPLIALGRYQAVLG
>A0A845B8U0|squalene-hopene cyclase|EC 5.4.99.17|Roseomonas coralli|TrEMBL
MTETLLHAAAAAGVPLDEAEAGLRRATEALLGLQREDGHWVFELEADATIPAEYVLLRHH
LAEPDDPELERRIGAYLRRIQAAHGGWPLFHGGAFDISASVKAYFCLKMIGDDPEAPHMR
RARAAILAAGGAGRANVFTRILLALYGEMPWHRVPTIPVEMVLLPRWFPVHLSKMSYWAR
TVLVPLLVLQALRVRARNPRGVRIPELFAARRARRRRMRTHRKPGWAAFFNTVDAGLKLA
EPLWPEPLRRRAIARCVDFVTERLNGEDGLGAIYPAMANAVMMYDALGYPPEHPDRAIAR
RAVEKLLVLREEEAYCQPCVSPVWDTALVCHALLEAGGEPATAAATRGLAWLKPLQELEL
KGDWAAWRPDVRPGGWAFQYRNPHYPDLDDTAVVVMAMDRARDQLRLGRNYDEAIARGAE
WTAGLQSRDGGWGAFDADNIHHYLNNIPFADHGALLDPPTADVSARCVSMLAQLGEAQDS
PRMRAALDYLEREQAADGSWFGRWGVNYIYGTWSALCALNAAGLDGATPMVRKAADWLLA
IQNPDGGWGEGCESYRLDHSGHEPAPSTASQTAWALLGLMAAGEVDHPAVARGIAWLLHN
QDETGLWPQEAFTGGGFPRVFYLRYHGYPKFFPLWALARYRNLRQANHTRPAHGM
>A0A7C1YE48|squalene-hopene cyclase|EC 5.4.99.17|Rhodospirillales bacterium|TrEMBL
MTHKAHSPQIQVSDRSHPHPVDGGAGPNGELDAVIDQAQAWLVERQGEDGHWAFELEADA
TIPAEYIMLNHFLDQTDPEVEGKLANYLRAIQEDHGGWPLYHGGDFNMSATVKAYFALKL
TGDDVDSSHMRRARDAVLAHGGAAKSNVFTRFALALFGQVPWRAVPIIRPEAILLPKWSP
FHIDKVSYWSRTVMVPLLVLAALKPRARNPRNIGVEELFTRPPEAEKNYHINPSGHWLGA
LLLKVDRAVRVFEPLFPKFLERMAIAKSMAFVKQRLNGEDGLGGIYPAMANAMMAFDALG
YGPDHPDRAICRKAIDRLLVFKDGMGYCQPCLSPVWDTGLACHALLVAGHKGDGPVIAKA
NEWLRGRQILDVEGDWAANRGHLRPGGWAFQYWNDYYPDVDDTAVVVMAMLRAQGDADRQ
AIGRAVEWIVG
>A0A832D634|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Rokubacteria bacterium|TrEMBL
MLPSGLVTGLHDAIARAQAHLLAVQAPDGHWIGELEADTTITAEQLLLCHLLDRVNVERQ
RKAVRYLRRRQRPDGGFDLYEGGPTNLSATIKAYFAMKMAGVPVTDPAMVKARERILEMG
GPTRANVFTKIQLALFGEYDWNGVPAMPVEIMLLPPPFFLFNIYEVSYWSRTVIVPLLII
MDRKPVKWLPPGQSLDELWPVPRERASLRFPRMPRPFAWRDLFWKNFFIAVDDGLKIWER
FSPRPLHKRAVEAARLWLEEHLGVPGGLGGIYPAMANSILAMRLLGYPDDHPLVAGQLKE
IEALAVESIDEIHYQPCVSPVWDTGLAVNALIESGLAPDHPALRRAGEWMLDRQVFTPGD
WAVKRPYVQPGGWAFQYDNPYYPDLDDAAMVLMALEKLRGLDPDRVRFSKERGLGWFLGM
QGQDGGWASFDADNNRLYLNNIPFADHGALLDPSTEDLTGRGLELLGTFGYGPDFEPARR
ALGFIRRNQRHDGPWFGRWGVNYVYGTWSVMRGLAAIGEDLRQEYVQRAVRWLERRQNPD
GGWGETCESYERPELAGRGQSTASQTAWALLALLAAGRAATPAVQRGAAYLVATQKPDGS
WYDTAWNGTGFPRVFMLKYHLYAKYFPLWALGIYRRALDG
>A0A6N2DV59|squalene-hopene cyclase|EC 5.4.99.17|Rhodospirillales bacterium|TrEMBL
MGYVGRLKAPITDTSVTNTSNLDAVIGETLGWLTRRQRSDGHWLFDLEADTTIPAEYILL
NHYLDEIDDATEGELAAYIRARQGDHGGWPLFPGGDLDISASVKSYFALKLVGDDPEAPH
MARARAAILAHGGAAKANVFTRITLALFGQVPWRAVPVIRVEAMLLPSWAPFHLDKVSYW
SRTVMVPLFVLAALKPRARNPRGIDIRELFVTPPERHRNYLTNPTGHWLGEVLLVLDRLA
RVAEPAIPKFLERKAIARAMAFVQTRLNGEDGLGGIFPAMANAVMAFDALGYSRDHPDYV
TARAAIQGLLSRESGETMCQPCLSPVWDTSLALHTLLEAGCEPDNHAVRNATDWLRKTQV
LDVVGDWASRKPDARPGGWAFQYRNDHYPDVDDTAVVVMALQRVGSDAVREAVDRGVEWV
LAMQSENGGWGAFDADNQHYFLEHMPFADHGALLDPPTADVSARCLGMLAQGGYDRDHPA
VARAIRFLKDEQEEDGSWFGRWGTNYIYGTWSVLAALNAAGEDMGAPYIRKAVAWLKARQ
RADGGWGEDCATYWPDRRNETKASTPSQTAWALLALMAAGEVDAPEVARGIAYLVDAPRD
EGKWQEGLFNAVGFPRVFYLRYHGYSAYFPLWALARYRNLRQSNTRRVAHGL
>A0A800DJG8|squalene-hopene cyclase|EC 5.4.99.17|Rhodospirillales bacterium|TrEMBL
MVKLEVVPHPTDGSKASKDFDLNGVDAVVEEARAWLADRQASDGHWAFELEADATIPSEY
IMLNHYLDEVDEDTESKLAAYLKETQGDHGGWPLYHDGDFNLSASVKAYFALKLTGEDIE
APYMRWARKAILEHGGAAKANVFTRFALALFGQVPWRAVPVIRVEALLLPKWAPFHINKV
SYWSRTVMVPLKILAALKPLARNQHGVDIRELFVKPAHEHRFYLTNPTGKFLGWVMLGVD
YAARMVQPLMPKWLERRAISKAVDFISERLNGEDGLGGIFPAMANALMAFDALEYPKDHP
DYVICRQAIDKLLVLRDDWGYCQPCLSPVWDTGLAAHAMLESGLTKGDPILAKANEWLLG
RQIFEVQGDWAANRGHVRPGGWAFQYWNDYYPDVDDTAVVVMALHRADPEKYREAIERGT
EWIIGMQSINGGWGAFDADNNHFFLQNLPFADHGALLDPPTADVSARCLGMLAQLGYETD
HPVMAKGLAFLRSEQEKEGSWFGRWGNNYVYGTWSVLCAFNAAGEDMQARHIRKAVDWLK
YVQRPDGGWGEDCSTYWQYRRDEVKTSTPSQTSWALMGLMAAGEVDSNSVSRGVEYLLNA
ERDGGNWHEEYFNAVGFPRIFYLRYHGYSAYFPLWTLSRYRSLKKTNSKFPKYGL
>A0A7Z9K4J9|squalene-hopene cyclase|EC 5.4.99.17|Rhodospirillales bacterium|TrEMBL
MLVDFALHLYSQRPLRPLRGLAIKKATDWMLERMQGNGGLGAIYPAMANSVLALHALGYG
TDHPLVSKALSEIEELEVESEDMLHLQPCFSPIWDTCLLTNTLVESGLSRTHPGLLKAGH
WMLSQQTKKVGDWKVSAPQAQPGGWCFQFENEHYPDCDDTAVVLMALAKLDFPNKAEQRQ
AIIRGLQWLLPMQGRDGGWASYDKDNNATMFNEHPFADHKSLIDGSTADIVGRVLEMLGV
LGFDRTFRPARKAIAYLKKDQEANGSWYGRWGVNYIYGTWSVLAGLRSIGEDLSQPYIRK
AVHWLKETQHDDGGWGESCQSYADQSLAGVGESTASQTAWALIGLLCAGEVQSDNVTRGI
ESLIRSQKPDGSWEERFHTGTGFPRVFYLRYHWYGQYFPLWAFSMYHSLKTRSRLRADDI
AKHNRRQGWYVQHSKKI
>A0A4Q2AGB9|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia stabilis|TrEMBL
MNDLTEMATLSAGTAPADVDAAVARATDALLAAQKADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARKAIHAMGGAEMSNVFTRIQLALFGAIPWRAVPMMPVEIMMLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANSVMMYDVLGYAEDHPNRAI
ARKSVEKLLVVQDDEAYCQPCLSPVWDTSLAAHALLETGDARAEEAVLRGLDWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLRQSDTYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTSDVSGRCLSMLSQLGETAA
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLGPEDPRIKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLV
AQQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNATRVTVGM
>A0A5B2V9J3|squalene-hopene cyclase|EC 5.4.99.17|Salinarimonas soli|TrEMBL
MLRADGRLWIDPPVSAPLDGGESSIVAEARAALVALQRPDGHWLFELEADVTISAEYIFL
QHYLDEIDPAEEGRIAAYIRGCQASNGGWPLFEAGEPDLSATVKAYYALKLAGDDPDAPH
MIRARSLILSLGGAAKANVFTRIALALFGQVPWRAVPAMPVELMLLPRRSPFHVEKISYW
SRTVIVPLLILMALRPQARNPRGVHIRELFLRPPEDEQAYITHPADARLGPAFLHLDRLL
REVEPRFPRGMRQRAIQAAIDFIEPRLNGDNGLGAIFPAMANVVMAFDAIGRPKDDPAVQ
TAKQAIRKLLVDGERTYCQPCLSPVWDTALAMHALLEAGETIEGAVLDRAAQWLLDREIA
ETRGDWTWKRPLLPPSGWAFQYRNDHYPDVDDTAVVAMALHRADPDRYRACLERACAWIV
GIQSRSGGWGAFDVDNTYHYLNAIPFADHGALLDPPTVDVTARCVSMLAQLGLGRDHDAV
RRGVAFIRREQEPDGSWYGRWGVNYVYGTWSALCALNAVGEPPDSPAMRRAGNWLKARQN
PDGGWGEDCASYAPAGRDRAYPSTPSQTAWAVLALMAAGEGAGEAARRGAAFLESAPRQG
ARWREEPWTGTGFPRVFYLKYHGYAAYFPLWALARYKRLLRGETRVPWGM
>A0A1Y6KMZ0|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. ORS 285|TrEMBL
MTVTSSASARAARDPGNYQTALQSTVRAASDWLIANQKPDGHWVGRAESNACMEAQWCLA
LWFMGLEDHPLRKRLGQSLLDSQRPDGAWQVYFNAPNGDINATVEAYAALRSLGFRDDEP
PVRRAREWIEAKGGLRNIRVFTRYWLALIGEWPWEKTPNIPPEVIWFPLWFPFSIYNFAQ
WARATLMPIALLSARRPSRRLPPENRLDALFPRGRDAFDYELPVKANAGGWDKFFRGADK
VLHALQNLGNRLNLGLFRPAATSRVLEWMIRHQDFDGAWGGIQPPWIYGLMALYAEGYPL
NHPVLAKGLDALNDPGWRVDVGEATYIQATNSPVWDTILTLLAFDDAGVLGDYPEAVDKA
VNWVLARQVRVPGDWSMKLPHVKPGGWAFEYANNYYPDTDDTAVALIALAPLRHDPKWKA
KGIDEAIQLGVDWLIGMQSQGGGWGAFDKDNNQQILTKIPFCDYGEALDPPSVDVTAHIV
EAFGKLGISRNHPSMVRALDYIRREQEPSGPWFGRWGVNYVYGTGAVLPALAAIGEDMTQ
PYIGRACDWLVANQQADGGWGESCASYMDISAVGRGTTTASQTAWALMALLAANRPDDKD
AIERGCMWLVERQSAGTWDEPEFTGTGFPGYGVGQTIKLNDPALSERLMQGPELSRAFML
RYGMYRHYFPLMALGRALRPQGHGSAER
>A0A3G8H7T1|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus pauculus|TrEMBL
MNQAATITRPHADAPSRRAMAASLPDPLDDGIAKAVDALLAQQRDDGHWVYELEADATIP
AEYILMVHYLGETPDAVLEGKIANYLRRIQGADGGWPLFHAGASDVSASVKAYFALKMAG
DDPEAAHMRRARARIHAMGGAEQSNVFTRTLLALYGVMPWQAVPMMPVEIMLLPEWFPFH
LSKVSYWARTVVVPLLVLNSLRPQARNPRNVGIDELFVRPCQATRLPRRAPHQSPLWVGV
FRALDAVVRVAEPLFPRRMRDRAIARARAFTVERLNGEDGLGAIFPAMVNAVMMFDVLGV
PPDDPDRAIARKSIDKLLVIRDDEAYCQPCLSPVWDTALAAHALLEVGEPRAIAAASRGL
DWLVPLQELELRGDWTVRRPDVRPGGWAFQYNNAHYPDVDDTAVVAAAMDRAERGDCSNR
YTPAIARACEWVIGMQSSNGGWGAFEPENTHLYLNNIPFADHGALLDPPTADVSARCLAM
LCQLGQMPASSEPAARALRYLLDEQEADGSWFGRWGTNYIYGTWSALCGLNAAGIGTDAP
EMQRAAQWLASIQNADGGWGESGDSYKLDYHGYEPAPSTASQTAWAMLGMMAAGAGDHPA
VARGVEYLLRTQAGDGFWDEPHFTAVGFPRVFYLRYHGYARFFPLWALARFRNLLREGNR
AVAWGL
>A0A7W5E592|squalene-hopene cyclase|EC 5.4.99.17|Rhodopirellula rubra|TrEMBL
MNLRRKFRHARRKFVLALSLAAVTPAFATTNVLSAQEKLPTGQDNTAQPAESAPSASEKQ
RRQLVEKGFQFLAQQGQSEAGTFSDRAGPGVTALAITSTIRNGHSVNDPTVAAGLKALEG
FVKPDGGIYGNGRIKNYETCVAMVCFAEANKTGKYSKLLQRAKAFVTDLQYAEGERDPSD
PWYGGVGYGGAGRPDLSNTAYMIEALRAVETQASDPAIQRALAFVSRCQNLDSQYNDTAF
ASKIDDGGFYYEIPTTKIDPSTSDERYTENGGLRSYGSMTYTGLKSMIFAGLTPEDKRVK
AAVEWIENHYTVEKNPGMGTAGLYYYYHTFAAALKTAGIQKLKDSDGFEHDWRADLIAEL
ARRQNDDGSWSNDNQRWFENDKNLATSFALMALSYCD
>A0A7K0IWE1|squalene-hopene cyclase|EC 5.4.99.17|Geobacter sp|TrEMBL
MNSSKYPISTALTSFNSEAAAPAIEKTRKAAGKVHHLPPSIWKKMVGDSKSPLDKAIEST
RDFFFREQLPDGYWWAELESNVTITSEYIMLFHFLGMVDKVRERKMAKNILSKQTENGSW
SIWHGGAGELSATIEAYFALKLAGYSADCPEMSKAREFILANGGILKARVFTKIFLALFG
EFSWLGVPSMPVELMLLPNWAYFNLYEFSSWARATIIPLSVVMSEKPVRKLPPSARVQEL
FVRPPRPTDYTFSREDGILTWKNFFIGADHLLKIYESSPIRPYKKKSIAIAEQWILEHQE
TTGDWGGIQPAMLNAILALHCLGYANDHPAVAKGLEALANFCIEDEESLLLQSCVSPVWD
TALALVAMQEAGVPTDHPALTKAAQWLLDLEVRRKGDWQIKAPELEPGGWAFEFLNDWYP
DVDDSGFVMLAIKDIKVRDKKHKEQAINRGIAWCLGMQSKNGGWAAFDKDNTKHLLNKIP
FADLEALIDPPTADLTGRMLELMGNFKYPQSHPAAAKGLEFIKREQEPEGPWWGRWGVNY
IYGTWSVLCGLEAIGEDMSQPYIKKAVNWLKSKQNLDGGWGEVCESYIDRSLMGCGASTA
SQTAWVLLSLFAAGEAKSGAAARGVEYLLATQKQDGTWDEDAFTGTGFPKFFMIKYHIYR
NCFPLTALGKYRRLTADSVDKQ
>A0A8D9S5F3|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia pseudomallei (strain 1106b)|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A7K3BK09|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8377|TrEMBL
MTATTDGGPGGEAARGTPSARTKTSGAIPEPASGPGTGGLTGRTEELAAEAARRATGHLL
ARQHPDGWWKGDLETNVTMDAEDLLLRQFLGIQDETVTEAAGRWIRSQQREDGAWSTFHG
GPGDLSATVEAYVALRLAGDAPDEPWMAAASAFVRERGGIARSRVFTRIWLALFGWWRWD
DLPELPPELIYLPKWVPLNIYSFASWARQTIVPLTIVAAHRPVRPAPFVLDELHTDPQRP
NPPVPRAPLSSWDGFFQRLDRALHAYRKVSVRPLRRAAMRSAARWIIERQENDGCFGGIQ
PPAVYSVIALHLLGYDLDHPVLRAGLKALDAFAVWPDKDTRMIEACQSPVWDTCLATIAL
ADAGVPADDPALVKAVDWMLGEQITKSGDWAVQRPGLPSGGWAFEFQNDTYPDIDDTAEV
VLALIRVDHPEPERVKASVDRGVRWNVGMQSKNGAWGAFDADNTSAFPNRLPFCDFGEVI
DPPSADVTAHVVEMLAALGLEHAPYTRRGIDWLLAEQERSGAWFGRWGVNYIYGTGSVVP
ALVAAGLPASHPAIRRAVRWLESVQNEDGGWGEDLRSYSSAEWVGRGESTASQTAWALLA
LLAAGEREGEAVRRGVRWLAETQNEDGSWDEPYFTGTGFPRDFSINYHLYRMVFPLTALG
RYVRGEPFGGLRKGA
>A0A3N8GDK8|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp8998|TrEMBL
MNDLTDMATLSAGTTPAGLDAAVASATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARKAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPIAKNPRGVRIDELFIDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AVDGLFPNYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDALGYAEDHPNRAI
ARKSVEKLLVVHEDEAYCQPCLSPVWDTSLAAHALLETGDARAEEAVLRGLDWLLPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLKQTDSYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTSDVSGRCLSMLSQLGESAL
SSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLI
AQQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A7W7ZTB4|squalene-hopene cyclase|EC 5.4.99.17|Granulicella mallensis|TrEMBL
MSTTPINPSNPGGTAPKQPRFGRLDMAMDLVIGGINRSVEWLMGEQEEPGYWCGELEADS
MLEADYIFMHTLLGSGDRGKMERCINEILRHQNADGGWSLYPGGPSNVHYGVKCYLALKL
MGWSADDPVLVRARENVLSLGGVVECNTFTKIYLCALGQYDYDAVPAVPPEMLLFPNWFY
FNIYEISSWSRGILVPLSVIYSTKPFKKLPPEQGIDELFVGGRANADLHLRWNKKQFFSW
RNFFLMLDRMMHWAERIHIRPLRKIALKKAEKWMLDRFEMSDGLGAIYPAMMNSIIALRY
LGYSEDDPQFIRAMDEFEKLGIEEPEVPGVHPARFRMQPCMSPVWDTAYAVFALGEAGVP
KDDPRLLKAADWMLSKEVRHKGDWAVKVKNVEPGGWYFEFNNEFYPDVDDSAQVLLALNC
VQNPRERYQYEVSQRALNWIFAMQCKNGGWASFDKDNTKQIFESIPFADHNAMIDPPTVD
ITGRILEMLSGYGFTRSDKRVEKAVQFILKGQEPDGSWFGRWGVNYLYGTFLVLRGLEAI
GYSYLEPAVQQAAEWIRMVQNTDGGWGETCGTYDDPNQRGVGPSTPSQTAWAILGLLAAN
DTRSDSVAKGIRWLIERQHEDGSWDELMPGRDGESYYTGTGFPRVFYLGYHLYKQYFPLL
ALTTYRKALEREQAEA
>A0A3T0MBK0|squalene-hopene cyclase|EC 5.4.99.17|[Brevibacterium] frigoritolerans|TrEMBL
MNQDVQSEINRLVHRLKQDQSADGSWNYPFDTGITADAYMIILLKILDMEDTPLIEALVK
RIESKQTENGSWKLFQDEKDGNVTVTIEAYYGLLFSGLRNKNHPHMRKAKQFILSKGGIK
QAKMLTKMMLTVTGQYQWPRLFPIPLEVVLLPPTFFVSIYDLSVYGRVNMIPLLLLGHKR
FQITTTDTPSLKDLFQTREDSSEEQVWEEYRTEEYRSFFSKLQTGVKTLIGYPDYLHSLA
LDSTKRFMLDRLEPDGTLYNYFGSTFFMIFALLSIGYSKRDPVILKAIAGLKGMACSIEG
HTHIQFTTPNVWNTSLISYALQEAGMPFKDKAVKAANQYLLSRQHYMYGDWLIHNPDAIP
GGWGFSDLNTMNPDVDDTTASLRALAKQLQAKPDNRDSWQRGVAFTISMQNDDGGFPAFE
RNNDHKWLQLLPIEGSKYLLTDPSTADLTGRTLEFLGNYTNMKKPEEVSKRAVDWLLEDQ
KRDGSWYGRWGICYLYGTWSALTGLKAAGQATGHPSIQKALTWLKKIQNEDGGWGESCYS
DIKQRYIPLGTSTLTHTAWAVDALISASEKPTAEIEKGIAYLIRAGQQESWTNDYPAGQG
MADFLYIHYHSYRYIYPLLALSHYNKKFLET
>A0A7G1Q8R3|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Nitrosacidococcus tergens|TrEMBL
MAHAIEKTIIEPTETQPDHKLDSAISRARDYLLKQQRKDGHWCFELEADCTIPAEYIIWT
HFTGELEPELERKLAVYLREKQADHGGWPLFYDGDLDISCSVKVYYALKFAGDDINEPHM
VRAREAILVRGGAARSNAFTRLTLAMFKQIPWRAVPLVPVEIMLFPRWFPFHLTKVAYWS
RTVMVPLAILYSLKAEAKNLNKVDIQELFTVPPEKERNYFPVRSQANKILLYVERVVRLI
EPIIPSFIRKKALKKAENWFVERINGIDGLGAIFPAMVNAHESLILLDYPPDHPVRNMAK
KALQNLIVDYGKSAYCQPCVSPVWDTGLAALALQEVENGKTTNQVIHALDWLKTKQILEH
PADWQEIHPNLKSGGWAFQYNNAYYPDLDDTSVVAWAMDQAGNSDRYGESITLACNWLRG
MQSSNGGFASFETNNMHYYLNEIPFADHGALLDPPTVDVSARCVALMGRLKRSEDSESLK
RALSYIRDEQEANGSWFGRWGTNYIYGTWSVLTALEQVGINPKEEFIRKAVHWLQEVQRS
DGGWGEDNYSYYDSSIAGTYKESTPIHTAWALLGLIAVGEGGSTTVKRGVEYLLANQNKN
SWNHLAFNAPGFPRVFYLRYHGYDKFFPLWALAKYRNYINNLC
>F0SK25|squalene-hopene cyclase|EC 5.4.99.17|Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / IAM 15109 / NBRC 103401 / IFAM 1448)|TrEMBL
MESGRQHARFLRVDEGHALGSERVVSDSTNAILDSIPEEQDTSPLGKAISATTDFLLSRQ
HSEGYWVAELEGDTILESEYILLMTYLGEQDSEDVQAAARYILEKQEDHGGWSLYPGGPT
EISASVKSYWALKILGHDPSAEYMQRAKAAILAAGGAEKVNSFTRYYMALLGLISYRQCP
AVPPELILLPSWTGVTIYEMSSWSRTILIPLSILWAFKPSRKLPAEQQIDELFIKSPRQL
PVVNDVSDKIDDLSYKTWVPWTWLFRQLDRGYKLIESIGEPPYRKMGIRLASTWMLDRFE
QSDGLGAIFPPIVWSLVALRCLGFEEDSSQIKETRRHLDELILRGTNAAGEPTVRLQPCK
SPVWDTAISTIALSETGQSNCEAAIQRSAAWMRSKEVRRKGDWSRSHPDVEPGGWYFEFN
NEFYPDIDDTTMVLMALARSLPTDMHADWTAEFVPQGDGEAEGRLETIISGKAPLWKGAI
ADVSRLQNVLDSMRRGVQWLLAMQSKNGGWGAFDADNDNELLTRVPFADHNAMIDPPTAD
ITARVMESLAMLGIDRNHPAMQEALAFVWKTQEADGSWVGRWGVNYLYGTWQVLVGLNAI
GIDKTDPRIRQAVRWLKDTQLDIGGWGESPATYEDPSLKGKGPATASQTAWALLGLMAAG
EAGSQAVQRGISYLLATQQEDGIWREEEFTGTGFPRVFYLKYHYYPVYFPLMALARYRQL
QRNG
>A0A3M1G2G9|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MLDKPLQGPPDLTDVDSVIAEAVAAMKSLQYDDGRWEFDLEADATIAAEYILLNHFLGDP
EVETEAMLGDYIRGLQGRHGGWPLFYEGDLDLSASVKAYYALKIVGDDTDAAHMRRARQA
ILDAGGAERSNVFTRYTLALFGQVPWRAVPVMPVELMLMPRWFPVTMARFSYWSRTVIAP
LLILAALKPKARNPRGVGIGELFAAPPATIADWLSNPTGSKWGDAFLLLDKLLRRVEPLF
PKGARQRAIDKAVSFISERLNGEDGLGGIFPAMANAVMAFDALGYGRDDPRFIVARQAVR
NLMTKGKDGPRFCQACISPVWDTALAAHALLEAGEESHAPVMDAAWDWLLTRQILDVKGD
WADKRPDLPPGGWAFQNRNDYYPDVDDTAVVGMALHRADPVAYEDAIKRAETWIVGMQSS
NGGWGAFDVDNDDYYLNNIPFADHGALLDPPTADVSARCLGFLAQLGHRRDEPVMARAIA
YLKREQEEDGSWYGRWGTNYIYGTWSVLVALAAAGEDMSAPYVRKAVAWLQERQMPDGGW
GEDGASYWRERRGEAKASTPSQTAWALLALMAAGEVDSDAVKRGVAYLTNAPRAGAKWRE
PWFTAVGFPRVFYLRYDGYSRFFPIWALARYRNLARANDKRVAWGM
>A0A849I715|squalene-hopene cyclase|EC 5.4.99.17|Enterovirga sp. DB1703|TrEMBL
MSPLRDGAFSNSLPANLDERIESATEALLRARRSDGHWCFELEADATIPSEYILLRHFLG
EPDDLELERKIGNYLRRIQADHGGWPLFHNGGFDISATVKAYFALKMIGDDPDAPHMVRA
REGILARGGAAAANVFTRFQLALYGEIGWDQLPNMPVELMLAPKWFPIHLSKMSYWARTV
IVPLLVLQVLKPRARNPRGIHVRELFAPPGSPPPPKKPSHAHPAWATFFNGLDVVLKKVE
PLWPSFLRGRAIARAVAFTTERLNGEDGLGAIYPAMANSVMMFDALGYPETHPDRAIARR
SVENLLVVKEDEAYCQPCVSPVWDTALASHALLETGDPRAEAAALDGAKWLRPRQILDVV
GDWAENRPGLRPGGWAFQYGNDHYPDTDDTAVVAMAMDRLRAKYPEGAENDESIARAREW
IAGMQSRNGGWGAFDIDNTYHYLNNIPFADHGALLDPPTVDVSARCVGMLAQLGEPKDSP
RMQQAVAYLINDQEPDGSWFGRWGVNYIYGTWSALCALNAAGIDPQSETVRKAVNWLVSI
QNPDGGWGEDCDSYKLDYRGYEPAESRASQTAWALLGLMAAGEADHPAVARGIAYLAAKQ
QEDGLWPEEDYTGGGFPRVFYLRYHGYAKYFPLWAMARYRNLKRSNSRQVTWGL
>A0A7W7YAA6|squalene-hopene cyclase|EC 5.4.99.17|Prosthecobacter vanneervenii|TrEMBL
MKHALFLLLTTSMVVAADPKPKPEFQYKTEGIQVSIPTADEPRVKAFGPDTIKAAAKYLD
DGAICWVREKTCVNCHTTGPYLSERPALSRQFGQPLEEVLADFVKTVPAEVKPQKETEKD
GIKYYGGSWTSIWRSLGLAEWDKHVTGKLSAHTERSLHEMLMRQSANGSFVSYGEVEIPH
ITTDFELTLQAARAVTSAPGWLSGLKDAELLARIEKMKSWLRTAEPKNDYDRILHLQLAH
YMPDLVPQAQRDAALALLSSKQHADGGWSLRDMSALSDWHFKMSDTVVKLVSNLPDAAKP
ESDAYMTAFAVVLMRQNNIPASDERIQRAVTWLKREQRVSGRWWMHSLYRGNYHYITYIA
TAQALKALALCDELH
>A0A7Y4H0X0|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium archetypum|TrEMBL
MLSIDKKIAVDSVATVDPIALEKSISSATEALLGYRQSDGHWVFELEADSTIPAEYILLR
HYLGEPIDSALEAKIANYLRRTQGNHGGWPLVQDGAFDMSASVKSYFALKMIGDSVDAPH
MVRAREAIRSRGGAAGSNVFTRFLLAFYGVLSWRAVPVLPVEIMLLPMWSPFHINKISYW
ARTTMVPLMVMAALKPLAKNPKGVGIDELFLQDPKSVGMNKKAPHQSWGWYALFSTLDKI
LRVVEPLFPKKLRQRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKGPDYPPR
AVTRRGIDKLLVIGEHEAYCQPCVSPVWDTALTCHALAEAGGEDTLKKMKQGLDWLKPRQ
VLDLKGDWAVKAPDVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRERRQTGSKDYDSAIAR
GREWIEGLQSRDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGET
AKTSKTVADGIAYLRRTQLAEGSWYGRWGLNYIYGTWSVLCALNAAGVDHQDPMIRKAAN
WLVSIQNKDGGWGEDAVSYRLDYKGYEGAPSTSSQTAWALLGLMAAGEVENPAVVRGVEY
LKATQNEKGLWDEARYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNSRVVGVGM
>A0A6P2C452|squalene-hopene cyclase|EC 5.4.99.17|Trebonia kvetii|TrEMBL
MTTAARRAPTRGTEAEGAKPGTVPAPASPVEAGTAAEVSGAPETRAAPAFAAIGDLAEVA
AATLTAARDHLLGLQDPRGWWIGELETNVTMDAEDVLLRHFLGILTDTDLKETAVWIRSQ
QRADGTWANFYGGPGDLSTTVEAYVALRLAGDQPDAPHMRTAAEWITTSGGLTATRVFTR
MWLALSGLWSWDALPVIPPEVIYLPSWFPLNIYDWGCWARQTIVALAVVSSFKPSNPLPF
TIDELYAATPGLPPKADQKDAWSVAFNTLDKALHKVEPKIPARARRAALRRCTDWIVARQ
EADGCWGGIQPPWVYSIMALTLMGYGLDNPIVKKALDGIEGFTIREDGMRRIEACQSPVW
DTVLTMVALEDAGLAADHPALVSAAGWLLDEEIRQPGDWAVRRPHTDPGGWAFEFENDNY
ADTDDSAEVILALRRVDLAERNPANRAAIRRGLRWLEGMQSKDGGWGAFDADNTRELINK
LPFCDFGAVIDPPSADVTAHIVEAFAAEGLASETACRRGVIWLLKNQEPDGSWFGRWGAN
YLYGTGAVVPALIAAGVRPHKPQIRRAVAWLESVQNADGGWGEDLRSYDDPNAWSGRGAS
TASQTAWALLALLAAGERDGAAVERGIRWLAATQRADGTWDEPYFTGTGFPRDFYLNYHL
YRLAFPVSALGRFVGGAGVVPRKEQSYVRGT
>A0A7W7LS53|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces olivoverticillatus|TrEMBL
MTATTDGTGAAEPRAAEAGHSTTVLPRTEAAGEPPKAREAAERAAARAVDHLLAHQDERG
WWKGDLETNVTMDAEDLLLRQFLGVGDEKTTEAAARFIRSRQRPDGTWATFHGGPAELSA
TIEAYVALRLAGDAPDAAHMAAASAWIREQGGIAAARVFTRIWLALFGWWKWEDLPELPP
EIMYLPKRAPLNLYDFGQWARQTIVPLTIVSALRPVRPAPFALDELHTDPRRPNPPRPLA
PATTWDGLFQRLDKALHLYHRFPVGPLRRAALNSAARWIIERQENDGCWGGIQPPAVYSV
IALHLLGYDLDHPVLREGLASLDRFAIWYEDAEGRPVRMIEACQSPVWDTCLAAVALVDA
GLRPDHPALVKAADWMLDEQVVRSGDWAVQRPGLTPGGWSFEFHNDNYPDIDDTAEVVLA
LRRVDHPQPRRVEAAVERAARWTLGMQSKNGAWGAFDADNTSKLPNKLPFCDFGEVIDPP
SADVTAHVVEMLAVLGMEHHPRTRRGIEWLLAEQEECGAWFGRWGVNYVYGTGSVLPALV
AAGLPASHPAVRRAVAWLEAVQNADGGWGEDLRSYRDPEWIGRGASTASQTAWALLALLA
AGEREGAAVERGVAFLARTQAEDGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRYL
HGEPFTAERRAG
>A0A502GE73|squalene-hopene cyclase|EC 5.4.99.17|Roseomonas nepalensis|TrEMBL
MNDAPGELLARNDEVWLEGIEAGIARAADALRAVQREDGHWVFELEADATIPAEYILLRQ
HLGEPEDPELERKIGAYLRRIQGEHGGWPLFHGGAFDLSASVKAYFCLKMIGDDPDAPHM
ARARAAILAHGGAGRANVFTRILLCLYGELSWKRVPTIPVEMILLPRWFPVHISRMSYWA
RTVLVPLLVLQAMRVRARNPRGVRIQELFVRARLRRRRGRTHQQRGWAMLFQAVDRVLTE
TNPVWPRPLRQKAIARCVQFVTERLNGEDGLGAIYPAMANAVMMYDALGYPPDHPDRAIA
RRSIEKLLVIREDEAYCQPCVSPVWDTALVAHTLLEVGGEAAEAVPRALDWLRPLQELEV
RGDWAEQRPHVRPGGWAFQYRNAHYPDLDDTAVVVMAMDRARTQLALGEAHDEAIARGAE
WTEGLQSSNGGWGAFDADNVHGYLNNIPFADHGALLDPPTADVSARCIGMMAQLGETPDN
PRMRAAIDYLEREQEEDGSWFGRWGVNYIYGTWSAMIALNAAGFDATRPSMRRGADWLIG
IQNPDGGWGEDCESYNLDYRGYEPFPSTASQTAWALLALMAAGEVDHPAVARGIAWLRDA
QDETGLWQQEAYTGGGFPRVFYLRYHGYPKFFPLWAMARYRNLRRGNARRVFHGM
>T2ILR2|squalene-hopene cyclase|EC 5.4.99.17|Crocosphaera watsonii WH 0005|TrEMBL
MQTQDRLTQKQPLSLKDAITASQNYLLSLQYPQGYWWAELESNITLTAETVLLHKIWGTD
KTRPLHKVEAYLRQQQREHGGWELFYGDGGEISTSVEAYMALRLLGVPQDDPALIRAKDF
IISKGGISKTRIFTKFHLALIGCYDWKGIPSIPPWIMLFPDSFPFTIYEMASWARESTVP
LIIVFNDKPVFSVDPVFNLDELYAEGVENVKYELPKNNNWGDIFLGIDQVFKFAEQVDLV
PFRKEGLKAAEKWILNHQQETGDWGGIMPPMLNSLLAFRTLNYDVNDPSVKLGFEAIDRF
SIEEDDTYRLQACVSPIWDTAWCVRALTDSGLEKDHFSLVKAGKWLLDKQVMEYGDWAVK
NKAGKPGGWAFEFTNRFYPDLDDSATVVMALNGIKLPDEARKQAAINRCLQWIETMQCKE
GGWAAFDLNNDQAWLNEVPYGDLKAMIDPNTADVTARVVEMLGSCDLEIESDRLNKSLNY
LYKEQEKDGSWFGRWGVNYIYGTSGVLSALAVINPEKHKTQMEQGINWLLSCQNKDGGWG
ETCRSYNDPSLKGKGVSTPSQTAWSLIGLLDAGEALNKFETDAIERGVNYLLDTQTEEGT
WEESEFTGTGFPCHFYIRYHFYRHYFPLIALGRYQNLSSEFGVRS
>I4GSY9|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa PCC 9806|TrEMBL
MQIQEKITEIAAKTAKAIELSQNYLLSTQYSDGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPANDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNNWSDVFLWLDGLFKWAEKTNLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVDDPIVARGLKAVDNFAIQ
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKSVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGSCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A0C4YTK9|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus basilensis|TrEMBL
MSQVALSPNSNEPAHAAPAPDELEGTLDRALDALLATQRPDGHWVFELEADATIPSEYVL
LVHYLGETPDTVLEARIARYLRRIQNADGGWPLFHQGRSDISASVKAYFALKMIGDDTES
EPMRRARAAIHGMGGAEASNVFTRTLLALFGVMPWQAVPMMPVEIMLLPLWFPFHLSKVA
YWARTVIVPLLVLNSLRPQARNPRGVGIDELFIRPCQAARLAPRAPHQKRVWFGLFRVLD
AGLRVAEPLFPRSLRARAIARAEKFVRERLNGEDGLGAIFPAMANAVMMFDVLGVPRTDP
DVAVARASIEKLLVVHGDEAYCQPCLSPVWDTSLASHALLEVGGPRAEAAVERGLQWLRP
LQVLDVRGDWIVRRPDVRPGGWAFQYANPHYPDVDDTAVVAMAMDRAARTGAAAPAVAPA
SHLSRYEEAVSRAREWVAGMQSGNGGWGAFEPENTHDYLNNIPFADHGALLDPPTADVSA
RCLSMLAQLGETAASSEAFRRAQRYLLDEQMADGSWYGRWGTNYVYGTWSALCALNAAGM
APEAPEMRRAADWLISIQNADGGWGEDGSSYRLDYQGYETAPSVPSQTAWAVLGLMAAGQ
VDHPAVARGVDYLMRMQQADGLWSEARFTAVGFPRVFYLRYHGYARFFPLWALARYRNLR
RDGTRAVAWGM
>A0A6A0BTD9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces rutgersensis|TrEMBL
MTATTNGPAGAAPSRPAPARPTTDTTTAPDSATVEAAAERARARAADHLLGLQSPEGWWK
GDLDTNVTMDAEDLLLRQFLGIRDEATTRAAALFIRGEQREDGTWATFHGGPPDLSTTVE
AYVALRLAGDSPDAPHMTRAAHFVRARGGIAEARVFTRIWLALFGWWPWDRLPELPPELI
FLPPWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPANPAPRTRLAPLA
SWNGAFQRLDRALHTYRKVAPRALRRAAMAAAGRWIIERQENDGCWGGIQPPAVYSMIAL
HLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALADAGVPADHP
QLVRAADWMLDEQIERPGDWSVRRPHLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHP
DTARLERAISLGVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDPPSADVTAH
VVEMLAAEGLGADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALIDAGLPAT
HPAIRRAVAWLESVQNDDGGWGEDLRSYRDQGRMARGASTASQTGWALMALLAAGERESA
AARRGVAFLADTQHEDGSWDEPYYTGTGFPWDFSINYHLYRQVFPLTALGRYTRGAAPEA
A
>A0A4P7WG02|squalene-hopene cyclase|EC 5.4.99.17|Acetobacteraceae bacterium|TrEMBL
MSILREKEAHKLGNASLKISSFSELLNAKLQAAQKALFQLQNEDGHWVFELEADATIPAE
YILLEHYLDRIDPQKEEKIGAYLRRIQGEHGGWPLYYDGNFDLSASVKAYYALKALGDSP
DSPHMKKAREAILQHGGAERTNVFTRILLALFGQVPWDAVPIMPVELMLLPRKSLVSIWN
VSYWSRTVIAPLLVLAALRPLAVNPRGVHIEELFRTRPSKVKDWIRGPYRSYWGYFFKGL
DVLLRKVEPFFSPRLRRKAIAKAISFIEARLSEGGLGAIYPAMANVVMMYRALGVSDKHP
LVQEAWQSIQDLLIETDKETYCQPCVSPVWDTGLASVALIEVLDGDQEDLKKQTRHQLEL
SADWLRKYQILDVRGDWAINASDEIEPGGWAFQYENPYYPDVDDTAVVGIFLHRLDPVKN
AFSIERARKWIIGLQSTNGGWGAFDIDNDLDILNQVPFADHGALLDPPTADVSARCVSFL
AQLGNAEDRDCLRKAVNYLRAEQEEDGSWFGRWGTNYIYGTWSVLSAFNALNISSTDPAI
KKAVNWLKLVQREDGGWGEDCASYEGAKPGTYRRSLPTQTAWALLALMAAGEINSKAVQR
GIDYLILEQNEKGEWEEGFHNAVGFPKVFYLRYHGYKHFFPLLALSRFKNLKENGRTRTS
WGM
>A0A086CI45|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Atelocyanobacterium thalassa isolate SIO64986|TrEMBL
MKTQHQINQKLKSSLDNAIDISQKYILSLQNSEGYWLGELESNVTLTAETVLIYKIWGIF
ENLSKSKIEAYLCNKQNKYGGWELFYGDGGEISTSIEAYMALRLLGLSKDNPVLVSARKF
ILSKGGISKARIFTKFHLALIGCYSWEGLPSIPPSIMVLSNNFPFTIYEMASWARESTVP
LIIVFDKKPIFPINPSFNLNELYVEDIEKVQYKLPYTNSWTDIFLWLDKIFQLLGKFNLI
PFRKRGLKEAEKWILDHQQESGDWGGIMPPMLNSLIAFKTLGYDIEDPSVKRGFEAIQRF
AIEKDQDYYVQACVSPVWDTAWMIRALTESGLSKDHRSLQIAGDWLLSKQCLDYGDWAIK
NKIGKPGGWAFEFTNRFYPDIDDSAAVIMALEGITLVNEQQKKAAINRCLQWIKTMQCKT
GGWAAFDIDNNQAWLNEVPYGDLKAMIDPNSADITARVLEMLGSCNLEMSDERTAKALNY
LYDEQEEDGSWFGRWGVNYIYGTSGVLSALAVLHPDKNYSQLKRGVSWLLSCQNEDGGWG
ETCLSYDNPELKGEGISTASQTAWSLIGLLDAGKALDNFAINHIDRGINYLVNTQTSTGE
WKEKEFTGTGFPSHFYIRYHLYSNYFPLIALGRYQKLRHLF
>A0A7K2NI73|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5468|TrEMBL
MTATTDGSAGAVPPRVPSASEPDPTTPVSHTLVAGEKARAVPLEEVAARTAERATASLLA
SQHPDGWWKGDLETNVTMDAEDLMLRQFLGIQDEKTLTAAARWIRSQQREDGTWATFYGG
PGEISTTVEAYVALRLAGDEPDAPHMAAASAWVRKEGGIAASRVFTRIWLALFGWWRWED
LPELPPEVIYLPKWAPLNIYSFGQWARQTIVPLTVVGAHRPVRPAPFTLDELHTDPAVPN
PPRPAAPLTTWDGVFQRLDKALHAYRKVNLRPLRRSALNTCARWIIERQENDGCWGGIQP
PAVYSVIALHLLGYDLDHPVMRAGLKSLDRFAVWYEDGSRMIEACQSPVWDTCLATIALA
DAGLPADHPALVKAADWMLDEQVVRRGDWSVRRPELPAGGWAFEFENDNYPDTDDTAEVV
LALKRVDHPDRARMRTAIDRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVID
PPSADVTAHVVEMLAAVGMADDPRTLRGIEWLLTEQETNGSWFGRWGTNYVYGTGSVVPA
LVTAGLPVSHPAIRRAVAWLESVQNADGGWGEDQRSYPDTGWAGRGASTASQTAWALMAL
LAAGERDGRAVERGIRWLAETQKEDGSWDEPYFTGTGFPWDFSINYHLYRMVFPVTALGR
YLNGEALARSGGELEQAA
>A0A7K3HDF1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5475|TrEMBL
DRLLHAYRRVAPPPLRRAALRACARWIVERQENDGCWGGIQPPAVYSVIALHLLGYDLDH
PVLRAGLDSLDRFAVWQDAPGPGGGPSRMIEACQSPVWDTCLATIALTDAGLPAGHPALV
RAADWMLGEQVLRPGDWSVRRPGLPPGGWAFEFHNDNYPDTDDTAEVVLALRRTAHPEPE
RVDRAVRRAVRWTLGMQSADGAWGAFDADNTSAFPNRLPFCDFGEVIDPPSADVTAHVVE
MLAAEGLAADPRVRRAVAWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALVAAGVPAEHPA
IRRAVDWLSSVQNEDGGWGEDLRSYPDPEWIARGESTASQTGWALLALLAAGEEDGKAVE
RGIGWLARTQREDGSWDEPQFTGTGFPWDFSINYHLYRLVFPLTALGRYLTAVGRQPRTV
PRDA
>A0A7V6CBE1|squalene-hopene cyclase|EC 5.4.99.17|Chromatiales bacterium|TrEMBL
AAARALRQLQAEDGSWCFELEADCTIPAEYILMMHFMDELDADLQSRLARFLRRQQMEAG
GWPLYPGGAFDMSCSVKAYYALKLAGDDVDAEHMQRARRAILDHGGAARSNVFTRIALAL
FGEVPWHAVPVMPVEIMFFPRWFPFSLARISYWSRTVVVPLLILMALKPRAVNPNNVRVQ
ELFAVPPEQERDWFPVRSRLGKLFLILDRMARPVDRIMPDWIRKRAIARAERWMIERLNG
EDGLGAIFPAMVNAHESLKLLGYPDKHPLREQTGRALRKLLVEMGDEAYCQPCVSPVWDT
GLTCLALQAAGPEGGNDESVRRGLEWLSRLQLDDEPGDWRDGNPDLPGGGWAFQYANPHY
PDLDDTAVVAWAMHEADRTASSHRYESAVQRAADWLCGMQSRNGGFAAFDRDNTSYYLNH
IPFADHGALLDPPTSDVSARCVALLSRLGRAQDRQALERVLDYLGSEQETDGSWFGRWGT
NYIYGTWSVLSALETVDNIPSGIRIDRAVAWLKDRQNSNGGWGESNDSYIAADRGALAST
AFQTAWAMLALIAAGEPADDPALCAGAEYLIRRQHEDGLWYDEVFTAPGFPRVFYLKYHG
YTAYFPLWALARYRALKSRQSGRLPVQ
>A0A6H9V059|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces luteolifulvus|TrEMBL
MTATTDGSTGALPPRAAAASDTDTDTPVAAGVHEAAARAAQRATDFLLSRQDDEGWWKGD
LETNVTMDAEDLLLRQFLGILDEATSHAAGLFIRGEQREDGTWATFYGGPGELSATIEAY
VALRLAGDAPDAPHMARASAWIREQGGIAAARVFTRIWLALFGWWKWEDLPELPPELIYF
PTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPDRPGPPKPLAPAASW
DGAFQRLDKALHALRKVAPRSLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSIIALHL
VGYDLQHPVMRSGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALVDAGVPADHPQI
VKAADWMLGEEIVRPGDWAVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHDP
ERVERAIGRGVRWNLGMQSRNGGWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLSKDPRTRRGIQWLLSEQEPDGSWFGRWGVNYIYGTGSVVPALTAAGLPAAHP
AIVRAVAWLESVQNDDGGWGEDLRSYKYVKEWSGRGASTASQTAWALMALLAAGEKDSKA
VERGVEWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPFAKK
PLAGAEGG
>A0A7W6SH52|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. cir1|TrEMBL
MDSVNATSRETLESKVLESSIASATQGVLGFQQADGHWVFELEADCTIPAEYILLRHYLA
EPVDTVLEAKIANYLRRVQGAHGGWPLVHEGEFDMSASVKAYFALKMIGDSTDSPHMVRA
REAIHARGGAINSNVFTRFLLATFGVVTWRAVPVLPIEIVLLPFWSPFHLNKISYWARTT
MVPLMVIAALKPRARNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFMLFRSLDAILRVI
EPLFPKSLRKRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKDENYPPRAITR
RGIDKLLVIGDDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLDWLIPRQELEV
KGDWAAKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGATGYDAAIARGREW
IEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETEKSS
KHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVRHDDPMIRKAAAWLAS
IQNEDGGWGEDAVSYRLDYRGWEAAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIAT
QNEKGLWDERRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A7X0GUD4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. AK010|TrEMBL
MPRWPHSALPAELVPATARLRSHLLGLIRPDGTLHSPCRSRVLESALLLALFDRARLEPA
ARSRLAAYLSLHCNSSEPLDRLMARAALHFRPDPAGLLDVERFLARAPDFTGPRKRALLH
AVLTLLDAAPTDDEIATAPEASSLHGLHTWARVQVTAVKAILAHARGHRLIDKGDLELLR
STQRPGTVWEANLLIHLSVLHALLPVPGQYPLVVEGVRTALRHQRPDGGMPFICDEDTWV
TATAGVALHAAGAGAPVVDLIARRLVALQDPSGGWSFTEGVQLPDVDCTSVAVEVLHLAG
PDTYRAPLQGALRALHALRGKDGGFPTYLAGAPSEACMTAAAANALSTQGPAYQREFASA
LSYIASQQRSDGSFPPDWSSSRLHTVSRAVLAASHDPRRGLGSLAQHIIRKAVALVADCQ
NADGGWGQQDGDASDALSTAYALTALTTQNTPGPAGRGVAYLLTQQRSDGSIASIPDSIG
PRPFGFTVPALADVFTLHALGHLTRRMESAPCRILPVTHADHGEGVIRSCPGCRQAGPGR
GVTGGSGGGQLWRTLRAADGHPVRPHQSSAPGAVRSRGKGR
>A0A8I1SQG9|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia bacterium|TrEMBL
MTPLARPVFPFESPELTLLAEPKSVEESIAKAQGNLLRQQRADGHWEAELLVDSTLCSDY
VLYMHWSDRVDEDLQRKCIAHIRRRQLSDGGWNIFINGPSEINASVKAYFALKLAGHSPN
APWMREARANILRLGGIPATNTYAKLYLALLGQFPWKYVPTIPPEIFLFPQWFFFNLSEM
SSWTRPILAPLTILNHFKPTRTLPAEFQLHELYPAGLENTDLSLKKEPRFWAWRNFFLRC
DQLLKIYNNLPFHPLRQHALKVAEKWMTERMGEGSEGLAAIFPSMLNSMMALKVLGYQDD
HPLVQKADRDFAGLFVDDPEDFRIQPCLSPVWDTAITTIALAESGLPGTNEAMQHAAQWL
EDREVRFVGDWAQRVSGIEPSGWAFEHDNKYYPDTDDTMMVLMALRHVPARDKVKRDAQF
QRALKWLLAFQCEDGGWAAFDKDVTARWLEHVPFADHNAILDPTCSDLTARVLELLGYIG
YDRSSTVVKRAVAMLRRTQETDGSWYGRWGVNYLYGTWQVLRGLAAIGENMDQEWIRRGR
DWLESCQNEDGGWGETCESYNFPALKGRGPSTASQTAWALMGLCACGDASRESIERGVAY
LTRTQEPDGSWTEDYTTGTGFPCVFYLKYEMYRQHFPLLALATYQQMVQR
>A0A3M1ISW6|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia bacterium|TrEMBL
MSATLPEGRPSHLVTTTGPRRAGAVPDVDPAIERAQRHLLGLQHPEGYWIGELIVDCTLA
ADMIVYHHWNGKVDPEWQRKAVNHILRLQLPDGGWNIYHGGPPEVNATIKAYLALKLAGV
PVTDPRMLKAREVALSLGGVPRMNTFSKLYLALVGLYPWKYVPTIPCEVLLIGKWFRVNF
WDMSNWSRAMLVPLAIINHFKPTRHVGVTLDELYREGYHERDLRLPRDPQWITWRNFFLA
LDKLHKFAELFARAGIHPFRRRALKKAEEWMLERFEGSDGLAAIFPAILNSLIALKALGY
PDDAPEVRETEAQLEKLTHYTEDELRIEPCLSPVWDTAITTIALRESGLPAGHPALVKAT
KWLLSKEIRFRGDWCHKNPADVEPSGWVFEFENKWNPDVDDTAMVLLALRLVPTDDPRAR
DAAYRRGLNWMLTFQCRDGGWAAFDKDCTNNILEKVPFADHNAMLDPECADITARVLEVL
GHERYPLDHPQVRRALEFLRAHQEPDGTWYGRWGVNYIYGTWQVLRGLHTLGVDMQQPWL
LKARDWLESVQHADGGWGERCNTYDDPVFKGQGPSTPSQTAWAVMALCTFGDPDRPSLRR
GVEYLIDTQNDDGSWSEEETTGTGFPKVFYLKYDMYRNTWPLLALATYRHLVRKTRINGT
RVPLRGRLTIQED
>A0A3N5J3H1|squalene-hopene cyclase|EC 5.4.99.17|Chroococcales cyanobacterium metabat2.561|TrEMBL
SSWARGSTVPLLIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKSNNWSDIFLWLDGLFK
WAEKTNLVPFRQESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDIDDPIVAR
GLKAVDNFAIETDNTYCVQPCVSPVWDTAWVIRALIESGLNPAHPAMIKAGQWLIAQQIL
DYGDWAIKNKIGTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKGVMKRAVNW
MATMQCKAGGWGAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVNMEEN
RVKKALDYLEKEQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYHQQLQKGANWLSGC
QNIDGGWGETCFSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLL
VTQKENGTWDEDYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A831UAT4|squalene-hopene cyclase|EC 5.4.99.17|Geobacter metallireducens|TrEMBL
MKSSKHPISHALTSFSDAAKDPSEDPRKKRGGKIHHLPASIWKKRDVETATPLDQAIEKT
QEFFLREQLPAGYWWAELESNVTITAEYVMLFHFMGLVDKAKQRKMAAYILSKQTPEGYW
CLWHGGPGDLSTTIEAYFALKLAGYPADHPAMEKARSFILANGGILRARVFTKIFLALFG
EFSWLGVPSMPIEMMLLPNGFTFNLYEFSSWSRATIIPLAIVMAERPVRKLPPWARVQEL
YVRPPRPTDYTFTKEDGILTWKNIFIGIDHILKVYEASPIRPGMKKAMAIAEQWVLEHQE
PTGDWGGIQPAMLNSVLALHVLGYANDHPAVAKGLQALANFCIEGDDEIVLQSCVSPVWD
TALALMAMVDSEVPTDHPALVKAAQWLLDREVRRPGDWKIKAPELEPGGWAFEFQNDWYP
DVDDSGIVMMAIKNVTVKDPKAKEEAIQRGIAWCLGMQSRNGGWGAFDKDNTKHILNKIP
FADLEALIDPPTADLTGRMLELMGTFGYPKEHPAAVKALQFIRENQEPDGPWWGRWGVNY
IYGTWSVLCGLRACGEDMGQPYIRKAVEWLVAHQNPDGGWGECCESYCDPKLAGTGPSTA
SQTGWALLSLLAAGQVDHPAAARGIRYLIETQKPDGTWDEEQFTGTGFPKYFMIKYHIYR
NCFPLMALGRYRALKRTRE
>A0A4Q1RXV2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. TM32|TrEMBL
MTATTDGSTGALPPRAPSASDATAGKTAASARVRSALGGDTADAARRATARATDHLLSAQ
DPAGWWKGDLETNVTMDAEDLLLRQFLGIQDPEVTEAAARYIRGEQCPDGTWATFYGGPG
ELSTTIEAYVALRLAGDAPDAPHMAKASAWVREQGGVAAARVFTRIWLALFGWWKWDDLP
QLPPELLYFPKWFPLNIYDFGCWARQTIVPLTIVSATRPVRPAPFALDELHTDPRRPNPP
RPLAPAVSWDGLFQRLDKALHLYHKVAFRRLRRAAMRSAARWIIERQENDGCWGGIQPPA
VYSVIALHLLGYDLDHPVLRTGLASLDRFAVRRADGARMIEACQSPVWDTCLATIALADA
GVPADHPQLVKAAEWILAEQIDRPGDWSVKRPQLPSGGWAFEFENDNYPDIDDTAEVVLA
LRRVKHPDPQRVEAAVRRAVRWNLGMQSRDGGWGAFDVDNTSPLPNRLPFCDFGEVIDPP
SADVTAHVVEMLADVGRTHDPRTRRGIAWLLAEQDPCGAWFGRWGTNYLYGTGSVLPALA
AAGIPRSHPAVRRAVRWLEGVQNDDGGWGEDQRSYQDKEQWAGRGASTASQTAWALMALL
AAGERDGEAVRRGVRWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRY
LNGGPAVAPVGS
>A0A8I2D3N8|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MTQKIGPLDIFKLIKPRGAAAAARPAPRRESPTLPHLPAPAEPPVTDALARARDWLLSLQ
NDAGYWVAELEADTTVESYFILFRTFMGRHDDPRIPKYAKTIRSCMLPQGGWAAYENGPP
DLSASVLSYFALKVAGISADEEDMRRATAVILNLGGIANANTYTKFYLAFFGQYDWSHVP
AVPPEMILLPSKIPINIYSISSWARAIFVPMSILYALKPVCAIPPECGVDELIVGGRENA
DLSLPRPPKVFSWSTVFLLTDKALKMAERFPIALARKAAIRRAERWMLARFERSGGLGAI
LPGMVNSIMALRCLGYPDDHPAIAKGLRDLEALEIHDPEDDSIRVQPCHSPVWDTAISTY
ALAVSGATIESEPRLRASVAWLLSKEVKISGDWKVKNPAPPSGWYFEFENEFYPDVDDTV
MVLMGLRTLHAPGVSPAVDGAIERGLQWVLGMQSANGGWASFDRDNDKNFLTNIPFADFN
AMIDPSTADITARVLEMFGTVAPEQYNPWHPAVRRALEFIRKDQREDGSWYGRWGVNYLY
GTWQVLRGLRIVGEDMRKDYVRAAVEWLMSVQHADGGWGERADSYDFPNRKGKGPSTPSQ
TAWALMGLLAAGEGHSQAARHGLKHLLDTQRRDGTWDETEWTGTGFPGVFYLRYHFYRHN
WPLMALSQYRRFLRGYRP
>A0A8B2QGB3|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cepacia|TrEMBL
MNDLTEMATLSAGTVPAGVDAAVARATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNVELEQKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFVDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AADGLFPNYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKSIEKLLVVHDDEAYCQPCLSPVWDTSLAAHALLETGDARAEEAVLRGLEWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAVAMDRAQKLRQNDAYRDSIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLI
ANQNEEGLWDEARFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNTTRVTFGL
>A0A7C2U2D5|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MTGPLYRDRQRLARAVQEAVRRSQDYFLRTQHPDGYWWGELESNVTMAAEYLMLTHILGV
ADPERWRKVANYLRREARPDGTWAIYYGGPPDLNATVESYVALKMAGAPADDPLLEKARA
FVLSRGGVPRVRVFTKIWLAMLGLWDWRGVPVLPPEFMFLPTWFPINLYEFASWARATIV
PILVILDRRPVWPVPEHARIDELFPVPPSQVDYRLPPPRRLLSWKGLFWGLDGLLRAYGR
VAFRPLREAAIKEAVRWIVARQEADGAWSGIQPPWVYSLIALRLLGYPLEHPVMRKGLEA
FEGAFRVEDETVYYPQACISPVWDTALAMIGLLDAGLPPDHEALVRAGRWLLKEQIFTGG
DWQFKAKGVEPGGWAFEFDNDIYPDVDDTAEVMMALHRTRLPEERRKAMALARGLEWVLG
MQCRDGGWGAFDKDNTQRLITHIPFCDFGEVLDYPTEDVTAHVLEMLGLLGYGADFPPAR
RALAFLRRKQDPEGPWWGRWGVNYIYGTGAVLPALRAIGEDMGRPYVRRAVRWLLSRQNA
DGGWGESCQSYEDDSLKGQGPSTASQTAWALMALLAAAPADGDGEVWESIGRGAAYLVET
QEEDGTWQEPHFTGTGFPRDFYINYHLYRNYWPLMALGRLQRLLSA
>A0A661VJ88|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MVMLSNSPKREDLERAIRRAREKLLRLQRPEGYWMGELEADVSVAAGYIPVMHFLGRKIG
EERTSRLIKFVRGRQNPDGSWPAYKGGPGDLSVSVQVYFALKLAGLSPEEEFMKRAREFI
LSRGGLTRTNVITKVWLACFGQFPWSATPTVPPELIFLPRWFYFNIYEFSSWARATIMAL
TLLSHLQPSCPVPDGRGVAELYPEGKQDHSLGQREGIISWENLYLLLDRLLKLYQKSPLK
PGRKRALSLVEEWVVAHQDADGSWGGIMLPWVYALFALKGLGYPDDHPVMKKGVEGLENF
IIEDEEGFRLQPAVSPVWDTAWAILALRESGLPPDHPALLKSARWLLRKEIRVRGDWAVK
NPGIEPGCWAFEFENNCYPDIDDSSVVPRALLQVRLPEPEERQKLS
>A0A0U5F8G3|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter ghanensis|TrEMBL
MNTISHPSKVKAAVSDSHTPTSATPTPFKGMDNSLAHTVAAACDWLIGEQKADGHWVGPV
ASNASMEAEWCLALWYLGLEDHPLRPRLGNALLQMQREDGSWGIYWGAGNGDINATVEAY
AALRSLGYPADTPALSKACAWIMRMGGLRNIRVFTRYWLALIGEWPWEQTPNLPPEIIWF
PNKFVFSIYNFAQWARATLVPLAILSARRPSRPLRPQDRLDALFPGGRENFDYVLPKRDG
MDLWSSFFRTTDRGLHWLQSKFLKRNTLREAAIKHMLEWIIRHQDADGGWGGIQPPWVYG
LMALHGEDYQFHHPVMAKALAALDDPGWRQDRGDASWVQATNSPVWDTMLALMALHDAGA
EERYTPEMDKALDWLLQRQVRVTGDWSIKLPGVEPGGWAFEYANDRYPDTDDTAVALIAL
SACRHREEWKKKGVEAAITRGVNWLIAMQSTCGGWGAFDKDNNRSLLSKIPFCDFGEALD
PPSVDVTAHVLEAFGLLGLPRETPSIQRGLAYIRAEQEPSGAWFGRWGVNYLYGTGAVLP
ALAAIGEDMTQPYITRACDWLVAHQQENGGWGESCASYMDVASIGHGTPTASQTAWALMG
LIAVNRPQDHEAIARGCRFLIDRQEEDGSWTEEEFTGTGFPGYGVGQTIKLDDPAVAKRL
QQGAELSRAFMLRYDLYRQFFPLMALSRAARIIPIKN
>A0A432K3P1|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MVAQEKHTPVEQAAGQAVRRSQDYFRRTQYPEGYWWGELESNTTMEAEYLMLCHFTGRHD
PERWRKVCNYILSKQRTDGSWGQYYEAPGDVSTSVECYFALKLAGHAPESDPLRKAREFI
LSKGGIPKVRIFTKIWLALFGQWDWKGTPKMPPEMIFLPSWAPFNIYEFASWARSTVAPM
LIILTRQPYCPVPESANIDELYPNGREGTNYTLPKPTGGFGWAKGLYWTDKLVGLYQRLP
VHPLRGRAEQKIMQWVLEHQEADGSWAGIQPPWVYSLIALHTMGYGPEHEAVKKGFQGFE
TFALEDEYKCNVQACISPVWDTCIAQLALLESGVAPDDPMVQSSARWLMDKQIFAGGDWQ
VRAKDVRPGGWSFEFDNQIYPDIDDASIVVMALDQVRLPEAEESRRADSIQRGVEWMAGM
QSKNGGWAAFDKDNNKKYLTKIPFSDFGETLDPPSVDVTAHLLEMYGRLGYTRDDAIVAR
GFEYVISEQEEDGSWFGRWGVNYVYGAGAVLPALEAIGEDMSQPYVRRAVDWLVAHQNED
GGWGESCGSYVDPTLRGVGPSTASQTAWALLGLVAAKEHDSETTQRGLAYLAETQEEDGS
WDEPYFTGTGFPGYGVGERLKALPDIGETSYQGLDMPAGFMINYHLYRNYWPLLALGRYF
QAISRR
>A0A8D9RRE6|squalene-hopene cyclase|EC 5.4.99.17|Nitrosococcus oceani AFC27|TrEMBL
MTRALRQAPESAGAIGIAAASPATETSGQDTHPREISGAITAARDALLKLQQADGHWCFM
LEADCTIPAEYILWTHFTGELEPEIERKLAARLRAKQASHGGWPLYEGGDLDISCSVKVY
YALKLVGDDPNAPHMRRAREAILAQGGGARANVFTRLALAMFSQIPWRGVPFIPVEIMLL
PRWFPFHLSKVSYWSRTVMVPLAILYSLKAQAQNPRNVHIQELFTVPPEQERHYFPVRSR
LNKILLSVERTARLLEPLIPSMLRRRALKKAETWFTERLNGEDGLGGIFPAMVNAHESLI
LLGYSPDHPWRVQAKKALQNLVIEEKNSASCQPCLSPIWDTGLAALALQETEGGHTTAPV
IRALDWLKERQILEQSGDWQVQHPNLKGGGWAFQYNNSYYPDLDDTALVAWSMDQAATPE
RYGEAIGRACDWLCGMQSRNGGFAAFESDNTHYYLNEIPFADHGALLDPPTADVTARCIV
LLGRLNKPQYAETLQRALDYLRREQEPNGSWFGRWGTNYIYGTWSALTALEQANIDPQEG
FIRKAVEWLKQVQRLDGGWGEDNYSYFDSSLAGRYQESTPVHTAWALLALMAVGEANSEA
VKKGIAYLLQIQQEDGLWDHPAFNAPGFPRVFYLKYHGYDKFFPLWALARYRNHLNRQC
>A0A3S3UKD9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. San01|TrEMBL
MTATTDGSSGAAAPGATSATTAQLTDTSPGAAGTHDAATRAVQRATDFLLARQDAQGWWK
GDLDTNVTMDAEDLLLRQFLGIRDEATTRAAGLFIRGEQRDDGAWATFHGGPGELSTTIE
AYVALRLAGDAPDEPHMAKASAWIRERGGIAAARVFTRIWLALFGWWKWDDLPELPPELI
YFPRWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDARNPNPAKPLAPVA
SWDGAFERLDKAMHLYRKVAPRRLRRAAMNTAARWIIERQEKDGCWGGIQPPAVYSVIAL
HLLGYDLEHPVMKAGLESLDRFAVWREDGARMIEACQSPVWDTCLAVIALADAGLPADHP
GLVKAAEWMLREQIDRPGDWSVRRPQLASGGWAFEFHNDNYPDIDDTAEVVLALRRVRHP
DIARMEKAIERGVRWNLGMQSKNGAWAAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTGH
VVEMLAVEGLSHDPRTRRGIEWLLAEQEPNGAWFGRWGVNYIYGTGSVLPALTAAGLAPS
HPAIRRAVAWLESVQNDDGGWGEDLRSYRYEDWKGHGASTASQTGWALMALLSAGERDSK
AVERGVAWLAGTQLADGTWDEPYFTGTGFPWDFSINYHLYRHVFPLTALGRYVQGEPFSD
RASLPGKGS
>A0A7K3EQ00|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5606|TrEMBL
MTATTDGSTGAALKPLAPSASEEDITVPAAAAGVPEAAARAVRRATDFLLSRQDAQGWWK
GDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFVRGEQREDGTWATFYGGPGDLSATIE
AYVALRLAGDSPDAPHMARAAEWIRARGGIAASRVFTRIWLALFGWWKWDDLPELPPELI
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAMPSPPRPLAPAA
SWDGAFQRIDKALHAYRKVAPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHP
QLVKAADWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVSHH
DPERVEKAIGRGVRWNLGMQSRNGAWGAFDTDNTSPFPNRLPFCDFGEVIDPPSADVTAH
VVESLAVEGLADDPRTRRGIQWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALTAAGFPTT
HPAIRRAVTWLESVQNDDGGWGEDLRSYRYTKEWSGRGASTASQTAWALMALLAAGERES
GAVERGVAWLASTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFA
AKKRPAPKAERPAGAPSTAEAKAG
>A0A7W9U2E0|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia bannensis|TrEMBL
MKKSDLPFAALLDAAIVRGRNALARRQQPEGSWCFELESDATITAEYILMMHFMAKIDTA
RQEKMARYLRAIQRLETHGAWDLYVDGAPDVSASVKAYFALKAAGDKENAPHMVRAREAI
LKLGGAAKSNVFTRILLATFGQVPWRATPFMPVEFVLFPKWVPISMYKVAYWARTTMVPL
LVLCSLKARAKNPHNVSIAELFVTPPEQEREYFARGKGVRRAFLVMDRLLRHVDPLIPGA
LRKRAIKHAEAWCAERMNGEDGMGGIFPPIVYSYQMMEVLGYPEDHPLRRDCENALEKLL
VERPDGSVYCQPCLSPVWDTAWSTMALEQSLTVPDTPAEEATEANIPRAELEQQIALAYD
WLAARQVDDLKGDWIENVKPDVPPGGWAFQYENPYYPDIDDSAVVVAMLHRRGRLQKQVT
GADPYAARVTLALDWMRGLQSRNGGFAAFDADCDRLYLNAIPFADHGALLDPPTEDVSGR
VLLCFGVTGREEDKASLARCIDYIKATQCPDGSWWGRWGTNYIYGTWSVLAGLALAGEDP
KQPYIARALAWLRSRQHADGGWGETNDSYIDPALAGTNGGESVSNFTAWALLAQMAFGDF
ESESVQRGIAYLLSVQDGEGFWWHRSHNAPGFPRIYYLKYHGYTAYFPLWALSRYRRLVS
AAQAKTHADTRESAKEKALAV
>C5B1M6|squalene-hopene cyclase|EC 5.4.99.17|Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1)|TrEMBL
MREAAVSKVETLQRPKTRDVSLDDVERGVQSATRALTEMTQADGHICFELEADATIPSEY
ILFHQFRGTEPRPGLEAKIGNYLRRTQSKVHGGWALVHDGPFDMSASVKAYFALKMIGDD
IEAPHMRAVRKAILQRGGAANANVFTRILLALYGEVPWAAVPVMPVEVMHLPKWFPFHLD
KVSYWARCTMVPLFVIQAKKPRAKNPRGVGVAELFVTPPDSVRTWPGSPHATWPWTPIFG
GIDRVLQKTQDHFPKVPRQRAIDKAVAWVSERLNGEDGLGAIFPAMVNSVLMYEVLGYPP
EHPQVKIALEAIEKLVAEKEDEAYVQPCLSPVWDTALNSHAMLEAGGHQAEANARAGLDW
LKPLQILDIKGDWAETKPNVRPGGWAFQYANPHYPDLDDTAVVVMAMDRAQRQHGLVSGM
PDYSESIARAREWVEGLQSADGGWAAFDADNNHHYLNHIPFSDHGALLDPPTADVTARVV
SMLSQLGETRATSRALDRGVTYLLNDQEKDGSWYGRWGMNFIYGTWSVLCALNAAGVDPQ
SPEIRKAVAWLIRIQNPDGGWGEDASSYKLNPEFEPGYSTASQTAWALLALMAAGEVDDP
AVARGVNYLVRTQGQDGLWSEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKRGNS
RQVQFGM
>A0A532EHP3|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp|TrEMBL
MKLFRTLFDRISSSLLATIPGKYNPAVGYAQTPPLRLVSDKVAPLAATDSSRRPSAHTVS
QPDAIDDAIRRSQSWFLSKQDPAEGFWVAELEADTTLTSEYLMLRRFLDCVDPVKEERAI
RYLRTMQLPDGGWPIYYGGPAEISASVKAYFALKLSGIPASDPCLLRARERIMAMGGVVQ
ANVFTKIALALFDQYDWEGVPHMPVEIMLLPKRFYFSIYAISYWSRAVLIPLLIVFAHQP
VCRIPREQGIEELYLVPRGQVPYWKYPPFNKDQAWFTPHNFFVMLDAVLKLYDRMPLLWL
REKAMHKAATWMLDHLKGNGGLGAIYPAMANSVLALRCLGYEMDDPLVQKALREIEDLEV
HETATVDGQRVPTLHLQPCHSPIWDTALLMNALIEAGMQQDHPALVKAGAYLMSRQTKTV
GDWTISSPQAEPGGWYFQFENELYPDVDDSAVVLMALAKLKMPEPADLRESIRRGMQWVL
AMQSSDGGWGAYDKDNNRVVFNYIPFADHKALLDPSTADLAGRCLEMLGALGYDRSHPAV
KPALAFLKKQQEADGSWYGRWGVNYIYGTWSVLAGLRAIGEDVSSPYIRRAVSWLESKQN
PDGGWGEVCLSYAEEAHSGKGQSTPSQTSWALMALMSAGVTESLSIARGVQYLLRHQLKD
GSWEEVMHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRSRGRMRAEELREQVESSGCY
RFDH
>A0A370VXJ9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. M7|TrEMBL
MTATTDGSTGALPPRAAAASDIHSETPLAAGVHEAAERAARRATDFLLARQDPAGWWKGD
LETNVTMDAEDLLLRQFLGIRDEKTTQAAALFIRGEQRDDGTWATFYGGPGELSTTIEAY
VALRLAGDAPDAPHMAKASAWIRDQGGIAASRVFTRIWLALFGWWKWEDLPELPPELIYF
PTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPANPNPPKPLAPVRSW
DGAFQRLDKALHQLRKVAPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLQHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALVDAGLPADHPQL
VKAADWMLGEEIVRPGDWAVRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPEP
ERMERAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIAWLLAEQEPNGAWFGRWGVNYVYGTGSVVPALTAAGLPGSHP
AIRRAVDWLESVQNEDGGWGEDLRSYRYAEEWSGKGASTASQTAWALMALLAAGERDSKA
VERGIEWLATTQRPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRFLHGEPFAGK
ATEAEGSG
>A0A7K2RWX8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8367|TrEMBL
MTATTDGSTGAAAPAASSATTAPTSDTTPEAAGTHHAATRAIQRATDFLLARQDAQGWWK
GDLDTNVTMDAEDLLLRQFLGIRDQATTDAAALFIRGEQRDDGTWATFYGGPGELSTTIE
AYVALRLAGDEPDAPHMAKASAWVRERGGIASSRVFTRIWLALFGWWKWDDLPELPPELL
YFPKWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDARDPNPAKPLAPLA
SWDGAFQRLDKIMHGYHKVALKKLRKSAMNSAARWIIERQENDGCWGGIQPPAVYSVIAL
HLLGYDLDHPVLKAGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPGDHP
ALVKAATWMLDEQIDRPGDWSVRKPALEPGGWAFEFHNDNYPDIDDTAEVVLALRRVTHP
DTARIEQAIERGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTGH
VVEMLAVEGRSHDPSTRRGIEWLLAEQEDNGAWFGRWGVNYVYGTGSVLPALTAAGMPAA
HPAIRRAVDWLESVQNEDGGWGEDLRSYRYEDWKGHGLSTASQTAWALMALLSAGERDSK
AVERGITFLAETQTEDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFKD
A
>A0A7Y5GEN6|squalene-hopene cyclase|EC 5.4.99.17|Bryobacteraceae bacterium|TrEMBL
MSATGTRLRESVSEAASRCARRAADALLRLQNPQGYWWGELTADSTLESDYILLQLWLHP
PDDDGIWRPPNRQRIDRAVRSILKRQLAGGGFNIYEKGPADLSATVKAYFALKLAGVPAD
DPALRQARGIILSLGGIQAANSYVKLNLSLFGLYPREHCPSIPPEMLLLPADFIYRMSSW
TRAIVIPLSIVHAADPRRPVPAGFDLRELFLVGASPAFRRSTKLFSWRNFFLGIDRGLKW
WERHGSRRVRARAVKRAEQWILERTRFSDGLGAIYPPMMYLIMALDVLGYAPEHPERQEA
QRQFDNLMVDDGERFFFQPCFSPVWDTGIAMQALGESGCAPEEPLAQAADWLLTKEVRRK
GDWSVKRPDLEPSGWYFEFANEFYPDIDDTAQVLLGLRHVRARDAAAQQACERRAVKWLL
GMQSKDGGWAAFDADNNWTPLSYVPFADHNAMLDSTCPDITGRVLEALCVYGLDRASPAI
RRGVKYLQRTQEADGSWYGRWGVNYIYGTFLALRGLQRAGESNREAYILRAGEWLRSIQN
ADGGWGEDCVSYQQGSFVPACSTPSQTAWAILGLLAGGDGDSLSVRNGIEYLIHTQRPDG
TWEEDLSTGTGFPRVFYLAYHLYRNSFPLLALSVYVNSHPAAGGAGK
>A0A5D4TAN8|squalene-hopene cyclase|EC 5.4.99.17|Sutcliffiella horikoshii|TrEMBL
MNTVNKINEKLKDMISNLLSAQSDNGAWNFCFEGSIMTDAYMIILIRTLKIKDEEILIKS
LVERIKSKQAPSGAWKVYPDEDKGNLSATIEGYFSLLYSGYVAKEATYMRKAEHFIREKR
GLAKSDWLTKMMLALTGQIKWPSIIKIIPIEIMLFPKWSPITIYQLVGYARAHWIPILIC
SNLNKSFVTPQTPNISHLQEGLSDSENERILEEMQNLQLYFKNALKKLSEAPEVLKQKAL
SKAEDYIIERIEENGTMYSYFSASFFMVFALFGLGYDRKHPLIQNAFQGMKSYLCRNADQ
VFIQNSPSTVWDTALLTAALQQAGVPHQHASILNANNYLFSRQHQKYGDWAIKNPDVTPG
GWGFSDINTFVPDIDDTTAALRAITPLTQTNILYKEAWNKGVEWILSMQNDDGGWSAFEK
NTDNYLLSFIPFKYEDRVLFDPSTADLTGRTLYFLGEYTTIPMESEIFQIAKEWFERNQE
VNGSWYGRWGNCYIYGTWAAVTGLKAIGVSNDDPVISLAVKWLLSIQNEDGGWGESCASD
IKKRYIPLNQSTPSQTAWALDALITVSETPTPKIESGIQALLSLLEADDWRSTYPTGAGI
PGGYYIHYHSYKYIWPLQALSHYKNKYDM
>A0A4Y7WG12|squalene-hopene cyclase|EC 5.4.99.17|Alkalihalobacillus lehensis|TrEMBL
MKIQAAIDTLVSKLREDQLEDGSWQYPFEAGTFTDAYMIILLRTLEKDDETLIQALAERL
LSLQEENGAWKLVKDENEGNLTTTVECYYALLYSGYLSKNDQRLQKAKQFILTNGGIEQT
TLLTKFVLLLTGQYKWPSFFPIPIELILLPVAFPFNLFSMSVYGRAHMVPLLIAADHKLQ
VTTSRSPDLSDLYSQSRNDPFLDWVDGEASRKLHGTIHYLVKKVIPGPTNIHQLAISQAK
RYMMNATEQDGTLFSYFTSTMFMVFALLALGHPKHDPLIEKAMEGLKSFQTTVNGKPHIQ
FTTATIWNTSLISYALQEAKVKPSDEMIQKASSYLVQKQHNTYGDWIVHNPGILPGGWGF
STINSIQPDMDDTTSSLRAITAQAVENEEIKEAWKRGTLWVTSMQNRDGGWGAFEKNTNS
RLLALLPIQESKGILTDPSTPDLTGRVIEFLGNFTHVPKDEKVLKRGIRWLKRNQQKDGS
WEGQWGVNYIYGTWAALTALDAAGVSKDEPHVRKAVNWLKSIQHQDGGWGESCLSDRNKK
FTKLPASNLTQTAWAIDALIATLDYPEKSIRDGVRYLLAHLHTSSDWTNAYPVGKGLADR
IYFHYHSYRYFYPLLALAHYQNKYNQS
>A0A552L1U1|squalene-hopene cyclase|EC 5.4.99.17|Microcystis flos-aquae Mf_QC_C_20070823_S10D|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWSDVFLWLDGLFKWAEKTNLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVDDPIVARGLKAVDNFAIQ
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKGVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVKMEEIRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A7C8EQ84|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MKSFDNSGTMARAADGQEVREDLDIGVGREPAAGCPEPVRLSEETGSPRSRQAATIRSSW
IPQIEAAIRKSSDYFFRVQYPEGYWWAELESNVTITSEYVMLTRLLGIPIAEKRSAIVKY
LLRHQNENGSWGLYYGDGGELSTTIEAYFALKLLGEDPGPGPLAKARAFILQHGGIEASR
VFTKMWLAQFDQYDWGKVPSMPVELVLLPPELYFNVYEFSSWARGTAVPLSIVLCIRPKF
ILPDSLCVRELFVPVYGKKLDSRINKLFFVFDRIAKILEKRPIRKLRRRAIAAARDWIID
HQEDSGDWGGIQPPMVYSLLALHYLGFPLSNEVMAKGLKAIEDFCIEDENGLRMQSCISP
VWDAALAALALLESGVSPERSALEKTARWLISQQILTGGDWQFKNSTPPGGWAFEFSNSR
YPDVDDSAVVLNVLNRFSPQRSDGLESAKSRGMEWLISMQSSNGGWAAFDRNNGMDILNR
IPFGDTEAMVDPPTADVTGRVLEVMGNCGYDCSHPAAKRGVRFLKNLQEKDGCWWGRWGV
NYIYGTWSALRGLISIGEDPKSPCIRAAMHWLKDHQNADGGWGETCDSYRLPELRGQGPS
TASQTAWAIMGLLAGNEEKSPEVSKGVQYLLRNQKPDGTWDEIYFTGTGFPKHFYIRYHN
YRNCFPLMALGQYVKNLGQ
>A0A6L8GXT2|squalene-hopene cyclase|EC 5.4.99.17|Acidimicrobiia bacterium|TrEMBL
MTTARGMPAALPWLASAAGTGDLEAEAADALARSVDALAGLQDPAGWWKGDLETNVAIES
EDLLLRAFLGIDDAEVTALTANWIRSKQSPDGGWSNRYGGPSDLSLAVEAYAALRLAGDS
PDAEHMRLAAEFVRDMGGVECARVFTRIWLALIGQWSWRDLPAIPPELILLPRWLPLNIY
DFACWARQTIVPLSIVSTYRPQVDLGVTLDELRTGAVPPERVPRSMRTPAGCFQRLDRVL
HKFHALAPWRLRETSMKLAEQWIIRRQESDGCWGGIQPQWIYSIIDQHLPGNQLDHPIQA
KALACFDSYEVRQGDMRWMECCQSPVWDTALAVVALGDAGLRRDDPAMTAAADWLLDEEV
RVRGDWAARRPHLAPGGWAFEFHNDNYPDLDDTAEVVLALGHAQAGDSERANAAIARAVA
WAEGMQCSDGGYAAFDADNVRRLCEQLPFCDFGEVIDPPSADVTAHVVEMLCWVRAHTDI
PVDARRLRRAVDWLWLDQESDGSWFGRWGVNHLYGLGAVLPALRAAGVPTSDRRIRRAVR
WLHASQGPEGGWGEDLRSYESDYWRGRGDPTASQTAWALLALMAADEFGEPTRRGVAWLA
RTCRSDGTWDEPQYTGTGFQGYFYINYHLYRQVFPTMALGRFLRATAGEAPSR
>A0A534Z8R5|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MSASEGRLTLVGGTAGEGLAARVAQAITRASQYLFATQHARGYWHAPLEANATMEAEYVF
FNRLLGRERPDVERRLAERLLALQQADGSWPIYHNGPGGPSTTIEAYFALKLTGMSATEP
ALVRARDFILGRGGLARAGVFTRIWLAYFGQFPWAGVPSMPVELVLLPPWFPLNIYAMSS
WARGTVVPLTLLLAHRPSVRLPAEAAVAELWLRAPTRDDLAFARSPELVTTRNFFLAVDR
ALKTLAPLSWRGLRRRAVARAIEWLLRHQDTNGQWGGIQPAMVNSVLALHAVGFAADHPA
MMSGIQGVEDFLVECEGTLMYQPCVSPNWDTALAARALLDAGLDPAHPALGRAAEWLVAN
QIFRPGDWAVLNPTLEPGGWAFEFANDWYPDVDDSAVILTVLDALPAAETAAGRRAIAYG
LNWTLGMQSRTGGWAAFDTDNTAAFLNRIPFADMEAMIDPPTEDVTGRVLHLMGTIGYRL
DFGRARRAVEFLRRTQRSDGSWWGRWGVNFIYGTWGALAGLERIGEDMRAPYVRRAVEWL
ATHQNPDGGWGETVASYDDESLAGKGESTPSQTAWALLGLLAADGPSSPAVERGVDWLVR
TQGPDGTWQERLFTGTGFPRHFYLRYHLYRHYFPLMALGQYRARLAARGEG
>A0A849BE13|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus gilardii|TrEMBL
MDHQDRPDSAASFASSFPPLTGSTACADSTDPRLEAAIAHAVDALIARQRADGHWVFELE
ADTTIPSEYVLLVHYLGEPADPAREARIGRYLLRRQNADGGWPLFHGGASDISASVKAYF
ALKMIGEPADAPAMRRARERILALGGAEASNVFTRTLLALYGVMPWRAVPLMPVEIMLLP
LWFPFHLSKISYWARTVIVPLLVLNTLRPCARNPRRVGIEELFRRPSQAARMPGRASHQG
RFWYAVFRGVDVALRVFEPLSPKTLRRRAIEQAERFVRERLNGDDGLGAIFPAMVNAVMM
FDALGVPRDEPAVAQARAALDRLLVEHGDETYCQPCLSPVWDTSLTCHAMLEAGGERALA
AARRALDWLLPLQVLDVRGDWTVRRPHLRPGGWAFQYANPHYPDVDDTAVVAMALDRAAR
GDARWQGGVEPALARAREWIEGMQSSDGGWGAFEPENTHSHLNSIPFADHGALLDPPTAD
VSARCLSMLAQLGELPANSRAAAQALRYLLDEQEANGSWYGRWGTNYLYGTWSALCALQA
AGLGPEAAPVRRAAQWLLSVQNGDGGWGEDGSSYRLDYRGHESAPSTPSQTAWALLGLMA
AGCRDLPAVARGIDFLLREQRADGLWDEQHFTAVGFPRVFYLRYHGYARYFPLWALARYR
NLQRVGNPANATGTADAAGRMPWGM
>A0A7W8N558|squalene-hopene cyclase|EC 5.4.99.17|Edaphobacter lichenicola|TrEMBL
MGISASNPKGVDQPAQPRFGRMDVGLDRITQGVARAKDWLFAQQHPDGYWCGELEADSML
ESDYIFMHTLLGTGEPGRMERAINEILRHQNDDGGWGLFPGGPSNISYGVKAYLALKLMG
WSKDHPVLVKAREWVLAHGGVVECNTFTKIYLCALGQYDYDAVPAIPPEIVLFPNWCYFN
IYEISSWSRGILVPLSIIYAKKPFKKLAPEQGIEELFVGGREHANLHLRWDKKKPFGWRN
VFLALDRIAHLAERVHIRPLRKIALKRAEAWMLERFEKSDGLGAIYPAMLNSIVALRCLG
RSVDDPQLIRALDEFEKLGIDCPDGTDDYSTPTFRMQPCFPPVWDTAQAMYALGEAGVRR
DDPRMLKAADWILSKEVRQKGDWAEKVKNVEPGGWYFEFNNEFYPDVDDTGQVLLALNCV
ENPRERYQYDACQRALNWIWAMQCKNGGWASFDRDNTKMIFQYIPFADHNAMLDPPTVDI
TGRMLEMLALYGVTRSDPRVEKAIQFILKEQEPDGSWFGRWGVNYLYGTFLVLRGLEAMG
FWNHEPAVQQAAEWIRMVQNADGGWGETCGTYDDPNQRGIGPSTPSQTAWAVLGLLAAGD
TRSDSVAKGIRWLVDRQHEDGSWDELVPGRNGESYYTGTGFPRVFYLGYHLYKQYFPLLA
LTTYERAMKSGTAH
>X5MK76|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Phaeomarinobacter ectocarpi|TrEMBL
MTVVEFGPSSDTDGAAERLAREELIKTQADQLLEMQRDDGHIVFELEADSTIPSEYVLLQ
HFLDEVDPAKEAKIANYLKRIQNEDGSWPLFQDGDGDISATIKSYWALKLTGEDIDAPHM
AKAREWVLSRGGASKANVFTRIMLALFAQIPWRGVPVIPVEVMLLPKWFPFHMSKIAYWS
RTVIAPLLILCSLKAEARNPTGINIHELFVTPPEDEKVYNINPNGTFVGDCFLVLDKVLR
FCEPAFPKSLRKRAVDKAVDFFTERLNGVDGLGAIYPAMANSVMAYDLLGYPKDDPNLMI
AKESIERLLVETDEELYCQPCVSPVWDTCLASHALMEAGFEAGDKELDGALDWLKDKQIL
DVVGDWAVRRPDVRPGGWAFQYNNDYYPDVDDTAVVAMAMHRTGKPEYNESIERAAEWVV
GMQSSSGGWGAFEPENEHFYLNSIPFADHGALLDPPTEDVTARCLSFLAQLDKDRFAKEI
ALGVKYLKRDQQDDGSWWGRWGANYIYGTWSVLCALNAVGEDMSAPYVQRSVAWLKARQR
ADGGWGEDLATYHEHRKSEVHESTASQTAWAVLGLMAAGEVESEEVRKGIAYLETAKRDG
ARWDEKLYTGTGFPKVFYLKYHGYAAYFPLWAVARYENLMKSNDRHVAYGM
>T2B090|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILGVIGDWAANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGSDNQAVVRAIGYLKRGQGANGSWYGRWG
>T2B062|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGRWG
>T2AZQ6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNGYYPDVDDTAVVVMALHRADPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDDQTVARAIGYLKRGQEVNGSWFGRWG
>T2AZE0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWGANARGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQTVARAIGYLKRGQEVNGSWYGRWG
>T2AYE2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAICAIALAESGLKRDHPFLVRACNWLVSKEIKIRGDWKVKRPKAPAGGWAFEFE
NQHYPDIDDTAMVILALRRIALTNISDQTACEQSILRGLNWLLTMQGRDGGWAAFDVDNN
KQIFTQVPFADHNALLDPSCADITARILETLGSLGYDLSYPEIQKGIKFLKKHQEPDGSW
FGRWG
>T2AXW1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPGLSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTKNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWL
>T2AZT1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTCIAQLALLESGIDPEDPMVQSSARWPMDKQIYATADWQARAKGTRPGGWSFEFD
NLIYPDVDDASIVVMALDQVRLPEAEEPRRADSIQRGVEWMAGMQSKNGGWAAFDKDNNK
KYLTKIPFSDFGETLDPPSVDVTAHLLEMYGRLGYTKEDRAVDRGFAYVISEQEEDGSWY
GRWG
>T2B075|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLATHAMLEANLSSGPRILENDSTSKACKWLENLQIKDCAGDWAVWRPNLRPGG
WAFQYRNDFYPDIDDTAVVAMALHRSENKIYEPTLLRAAEWIIGMQSKNGGWAAFDADNE
YYLLENMPFADHGALLDPPSADVSARCISFLTQMGHDQTNGTIKRG
>T2B0F0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLNGLSLLESGLTLKDSSIQKACKWLEKKQILEIKGDWIVNNKNLLPGGWAFQY
ENDFYPDVDDTAVIVMFLDRAGYQNKKRLEIACNWIVGMQSKNGGWGAFDKDNTYHYLNN
IPFADHGALLDPPTADVSARCISMLSQINKKNYKKIIQKGVKFLKNEQENDGSWYGRWG
>T2AZD5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLSGISLLESGLTLKDIAIRKACTWLEKKQILEMKGDWVANNKNLLPGGWAFQY
ENDFYPDVDDTAVVAMFLDRAGYQNKKRLERACNWIIGMQSKHGGWGSFDKDNTYHYLNN
IPFADHGALLDPPTADVSARCISMLSQINKKNYKNVIQKGVEFLKNEQEEDGSWYGRWG
>T2B014|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLSGISLLESGLTLKDIAIKKACTWLEKKQILGMKGDWVANNRSLLPGGWAFQY
ENDFYPDVDDTAVVAMFLDRAGYQNKERLERACNWIIGMQSKNGGWGSFDKDNTYHYLNN
IPFADHGALLDPPTADVSARCVSMLSQINKKNYKNVIQKGVEFLKNEQEEDGSWYGRWG
>T2B077|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAALALQEADPKGTRQSREKAYNWLKTKQLDKQPGDWQIRQPHLEGGGWAFQF
ENPHYPDVDDTAVVAFAMANADLPNLNESINRATRWTAGMQSKNGGFGAFDCDNTDYYLN
HIPFADHGALLDPPTADVSARCAMLLGHQIKNHPEYQTTLDGTIAYLRSEQETDGSWFGR
WG
>T2B097|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
VWDTCIAQLALLESGIDPEDPMVQSSARWLMDKQIYAAADWQVRAKGTRPGGWSFEFDNL
IYPDIDDASIVVMALDQVRLPEAEEPRRADSIQRGVEWMAGMQSKNGGWAAFDKDNNKKY
LTKIPFSDFGEALDPPSVDVTAHLLEMYGRLGYTKEDRAVGRGFAYVISEQEEDGSWYGR
WG
>T2AZB4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAAHAVLETHGGNTHLLNKSCDWLSKLQIKGHTGDWGWRRKGLRPGGWAFQYN
NKFYPDVDDTAVVGMALHRQDPEKYADTISRAEEWIIGMQSSNGGWAAFDADNEYYILEN
LPFADHRALLDPPTADVTARCISFLTQIGTSNNHPISRGLEFLKRNQEEDGSWYGRWG
>T2AYT6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWIAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGSW
G
>T2AY81|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTASVSQALIETEYKQHVSTEIETALNWLKEQQLSDDPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGRW
G
>A0A6I7Y7F8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. col6|TrEMBL
MTATTDGSTGAVDPRAASASRPTIESTIAADGVLAAARRAAERSVEHLLGRQDEQGWWKG
DLATNVTMDAEDLLLRQFLGIQDPATLRAAAGFIRGEQLGDGTWATFHGGPADLSTTIEA
YVALRLAGDRPEDPHMARAAGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMF
FPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTEPDDPNPSKRPAPAVS
WDGLFQRLDKALHVYHRFAPRALRRIAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVMRAGLDSLDRFAVWREDGTRMIEACQSPVWDTCLATIALADAGVAPDHPA
LVKAADWMLAEEIVRPGDWAVRRPRLEPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPD
QARVDAAIERGVRWNVGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHV
VEMLAIEGRAAHPVTRRGIEWLLSEQDAGGGWFGRWGVNYVYGTGSVVPALTAAGLPVSH
PAIRRAVQWLESVQNDDGGWGEDLRSYTEEKWIGQGASTASQTAWALLALLAAGRRDTVA
VTRGIAWLTETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFAGR
APMREGA
>A0A849UYU2|squalene-hopene cyclase|EC 5.4.99.17|Methyloglobulus sp|TrEMBL
MLTETSSPPGLNTGFTESAYSPPSLDSAIALATKELLGLQNEAGFWVFELEADCTIPSEY
ILMMHFMDEIDEGLQTKIANFLRTQQSADGSYPLYRGGTGDISCTIKAYYAMKMAGDSIH
ATHMQKAREWILAKGGAAKGNVFTRIMMAMFEQIPWRGVPYMPVEIMLLPKWFPFHLDKV
SYWSRAVMVPMFILCTYKVKARNPHKIGIAELFVTPPNKERNYFSHVKTPLGKAILVVER
VGRLMDPLIPGFVRRKATAKARDWFMERLNGYDGLGAIFTAMVNAYEAMDLLGIPADNEQ
RRVARAAIDRLLVIKDDMAYCQPCVSPIWDTGLTSLVLQEVDRYEHNSQTQQAIKSALHW
LTSKQLRDEPGDWQRQRPNLPGGGWAFQFSNSYYPDVDDTAVVALALVQADEREFAENIG
RAGIWIAGMQSRNGGYGAFDADNDHYYLNHIPFADHGALLDPPTADVSGRCIMLLGKLVH
QHPEYQAVIDNCIAYLRTEQEKDGSWFGRWGTNYIYGTWSVLAGFETAGVSKDDPCIRKA
VTWLKSKQRTDGGWGEDNYSYHGNNIHGVFHTSTAFHTSLALLAMLSAGEAGCREVESGV
NYLLKTQQASGFWNDKSFNAPGFPKVFYLKYHGYDKFFPLWALGRYRNEQFAA
>A0A6B0W4L0|squalene-hopene cyclase|EC 5.4.99.17|Holophagales bacterium|TrEMBL
MIGPAGVLKERSKTAPARNLNQTIEAAARNLLSSRKEDGHWRFELEGDTILESEYVLLLY
FLGRADDPRIAACCRRLRSQQMPSGGWATHPGGRVDPSVSVKAYLCLKLAGDDPRSPHMA
AARRAILGAGGLRACNSYTKLYLAIFGLWRWRHAPAVPPEMILLPRWFCFNIYDMSSWTR
AMVVPLSVIWAHRPNVPLDVTLDELETEFVPAPVRPPLIKLFWAQGFTALSALLKLVEWI
GPLPWWRRRALLKAERWLTERIECADGLAAIFGAIVNAVIALRCLGYDVSHPLVQAQLRE
LARFEIEEAGEVRLQPCLSPVWDTTLTVNALLDAGVDDGRAPIQEALEWLLDREISVAGD
WRQGSLQEAPGGWCFEYRNDYYPDCDDTAEALLALARVRGRFALEARRQEALARGLSWLL
GMQNPDGGWAAFDRGCDKEVLTFIPFADHNAMIDPSTPDITSRGIRALLAAGLDPREAPV
RLAAGYLLRQQEEDGSWPGRWGANHIYGTGLSLGALGEFASAAPRDGSDTLARALRRGRN
WLLRVQNGDGGWGESLGSYDDPTARGRGDSTASQTAWAMLGLSAAVRARPEPRESGAARA
ALDRAAAFLQERQREDGSWYDRWWTGVGFPGVFYLRYHGYAQYFPLAALAAYRRLRSGSR
G
>A0A107Q7D8|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia territorii|TrEMBL
MNDLTDMATLTAGTVPAGLDAAVASATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEEKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPIAKNPRGVRIDELFIDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDALGYAEDHPNRAI
ARKSIEKLLVVHEDEAYCQPCLSPVWDTSLVAHALLETGDARAEEAALRGLDWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLKQTDTYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGESAL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRVKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGVEYLI
AQQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>R9W2Q6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALASHALMESAGHQPEAGHGANAAPVAKALAWLKPLQVLDVVGDWGMARPDAPP
GGWAFQYANPHYPDLDDTAVVVLAMDRATKTLPLIAVAAETEYAAAIERARLWVEGMQSR
NGGFGAFDADNDRDYLNYIPFADHGALLDPPTADVTARCISMLSQLGQTRETSPALARAV
DYLLAEQEKDGSWYGRWGMNYIYGTWSVLSALNAVELDHESEAIRRAVTWLKEIQNDDGG
WG
>A0A2N8NZC3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces eurocidicus|TrEMBL
MTATTDGSTGAPTLRAAAAKDSTTVTPPLEHGGPAAAPTAAERATARAVDHLLSRQDAEG
WWKGDLQTNVTMDAEDLLLRQFLGIQDERTTRAAALFIRSEQRPDGTWATFLGGPPELSA
TIEAYVALRLAGDAPDAPHMATASAWIRAHGGIAAARVFTRIWLALFGWWKWDDLPELPP
EIMYVPKWIPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPRRPNPPRPLA
PAASWDGVFQRLDKALHRYRRFPVRPLRRAALNAAARWIIERQENDGCWGGIQPPAVYSV
IALHLLGYDLDHPVLRAGLASLDRFAIWREDGSRMIEACQSPVWDTCLAAIALADAGVAA
DHPALVKAADWMLDEQILRPGDWTVRRPELPPGGWAFEFHNDNYPDIDDTAEVVLALKRV
AHPDPARLDAAVERAVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADV
TAHVVEMLAVLGRQHDPRTRRGIEWLLAEQEENGGWFGRWGVNYVYGTGSVVPALVTAGL
PASHPAIRRAVRWLESVQNDDGGWGEDLRSYRDPEWIGRGASTPSQTAWALMALLAAGER
DGKAVERGVARLVETQEEDGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEP
FAADRQEA
>R9W0C7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAITACGTLESAAKGGIASVKNGLDWLVPKQVLDVRGDWIARRPDVRPGGWAFQY
ANPHYPDVDDTAVVAMAMDREQNLSGHKSYDPALARAREWIVGMQSENGAWGAFDADNEY
YYLNNIPFADHGALLDPPTEDVTARCLSMLAQFGDTLEGGEPMRHGVDYLRRTQLAEGSW
YGRWGMNYIYGTWSVLCALNAVGVDHDGAGSAKAAQWLLDIQNPDGGWGE
>V5V678|squalene-hopene cyclase|EC 5.4.99.17|Thermosynechococcus sp. NK55a|TrEMBL
MPTPLTTAIDPKQLQQAIRASQDFLFSQQYAEGYWWAELESNVTMTAEVILLHKIWGTEQ
RLPLAKVEQYLRNQQRDHGGWELFYGDGGDLSTSVEAYMGLRLLGVPETDPALVRARQFI
LVRGGISKTRIFTKLHLALIGCYDWRGIPSLPSWIMLLPEGSPFTIYEMSSWARSSTVPL
LIVMDRKPVYAMDPPITLDELYAEGRANVVWELPRQGDWSDVFIGLDRLFKLFETLKIDP
LREQGLKAAEEWVLEHQEPSGDWGGIIPAMLNSLLALRALDYAVDDPIVQRGMAAVDRFA
IETETEYRVQPCVSPVWDTALVMRAMVDSGVAPDHPALVKAGEWLLSKQILDYGDWHVKN
KKGQPGGWAFEFENRFYPDVDDTAVVVMALHAVTLPDENLKRRALERAVAWIASMQCRPG
GWAAFDVDNDQDWLNTIPYGDLKAMIDPNTADVTARVLEMVGRCQVAFDSGALDRALAYL
RNEQEPEGCWFGRWGVNYLYGTSGVLAALSLVAPPYDRWRIRRAAEWLVQCQNADGGWGE
TCWSYNDPSLKGQGDSTASQTAWAIIGLLAAGDATGDYAAEAIEKGIAYLLETQRPDGTW
HEDYFTGTGFPCHFYLKYHYYQQHFPLTALGRYARWRNLLAS
>A0A3S0DSC7|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobiaceae bacterium|TrEMBL
MTSDHSSAPNAQALAASISAASSAIQSQRQADGHWVYVLEADATVPAEYVLMRHYFAEPV
DAALEAKIGNYLRRMQLANGGWSLFHGHEFDMSASVKAYFALKMIGDSIDAPHMKKAREI
ILAHGGAVKSNVFTRILLALYGVLTWHAVPVMPVEIMLLPRWFPFHLNKMSYWARTVIVP
LLVVMLYKPRAKNPLGVTVDELFLEDPKSIGPTPKAAHQSQLWFTSFDIIDKVLRIADPF
FPKATRKRAIARAEAFVTERLNGVDGLGAIFPAMVNSAMMYDLLGYPKDHPNFVAARQSI
EGLLVFEGDEVTCQPCVSPVWDTALASHAMIEAGSEAEVKSAMAALDWLKPRQVLDLKGD
WAVKRPDVRPGGWAFQYNNAHYPDLDDTAVIVMAMDRARRLGAGNKYDDAIARAVEWIVG
MQSKDGGFAAFDADNLEYYLNNIPFADHGALLDPPTEDVTARCVSMLAQLGETAESSPAM
ARGIDYMRRTQQPDGSWFGRWGINYIYGTWSVLCALNAAGVPHDDPAMTRAVDWLVSIQN
EDGGWGESGSSYKLDYKGYEKAESTASQTAWATLALMAAGKVDHPATQRGIGYLMGAQTP
DGLWTERYYTGGGFPRVFYLRYHGYSKYFPLWALARYRNLRNSNSRFAGVGM
>A0A849W6R5|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Brocadiae bacterium|TrEMBL
MSIEIESPEEFLDDYKDPKDFQKILEHIQKKRFLKKFSRLNLNPGQQNTLEAMQKAQRWL
LAQTCGKPYWDAPIEANASLSAQFILMALGMQFQDKDKLEKLFQYVISKKDEKGLYPLYY
GGPAHYSTNLLIYLAGRALGYSKDSGCLSTLYEYLRKTNIHTATNMETRLLLAAYGLIDW
NAVPPITPLLMLIPQEADFTIYSISYWVRTSLVPMMILWTLKYQFPSFPLAPEEILDLHP
EKKSFPPFEAKNRLWDGFIRNLDSLCSLNMKEMEKLAVKKAELWTLQHQDESGDWGGIYP
AMQYSLMGLYASGYALDHPVMEKGMQALFRFQKDIQGKLHQQSCVSPVWDTAWSLIALYN
SGIDLSSFSPHFVWLRENQIFQEGDWAVCNKTGFGGGWAFQFSNVWYPDTDDSAVVIMSM
LNHPSPDAGMLQSIRTGVRWLLTMQNPDGGWSAFEQGVDDDYVDKIPFNDMENWKDPSTA
DVTGRCLQMLGELKVEPNLPCVRKAVAFLLKTQEKDGSWFGRWGVNHIYGTWSVIMGLKH
FLPQDAPAIQKAVEWLESIQKEDGGWGESCDSYIQGCYIPLECSTASQTAWAILALIHAG
KAHSPCVQKGIEWLVSHQTLDGTWEEKHFTGTGFPKHFYLRYDYYRHYFPLWALGEGLYE
TSSSKRVLSDEK
>A0A6N9E292|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp. SB0677_bin_15|TrEMBL
MDLLINFLGRLSQSFFPPAPHKAQPRHWNPRTPSLKLVSGNRGVAGDVECVQSRTAPATV
GHAEAVEEALSRSARWLLGQQHPEQGYWVQELEADTTLTSEYVMLRRYIGAVDTEQEARM
VRYLQGAQLEDGGWPIYTGAPMDVSASVKAYFALKLAGVPQDDPGMRRARQAILDKGGVV
SANVFTKIALALFGQYDWKGLPSMPPEVVLAPKKFAFNMYAISYWSRAVVIPLLIVFAVR
RECRIPAERGIEELFCTPRDQINYRYAPPFQKDPEFISWRNFFVWIDRILKVYEKYPLRS
VRKKAMKRAEAWLLEHMQGDGGLGAIYPAMANSIFALMALGYPASHPLVQKALREIEALE
IDTPDSAEGPSTLHLQPCHSPIWDTALTINALIERGLPVDHEALSHASSWLRSRQTQKVG
DWVVSSPGATPGGWYFQFENELYPDVDDTAAVLTALAKVSPLQPADRDEVIQRGLKWALA
MQSSNGGWGAYDRDNDQLIFNKIPFADHQSLLDPPTADLTGRCLEMLGALGYDRSHPAVA
PALEFLRREQEADGSWYGRWGVNYLYGTWCVVVGLQAIGEDMSAPWIRRAVAWVESKQNI
DGGWGESCLSYADRAWAGKGESTPSQTAWALLTLLTAGLSDSLSIARGVNFLLRHQLDNG
TWYEPYHVGTGFPRVFYLRYHGYSKYFPMWALAMYRNVRMHGQTRSQALQDVAQSARQRQ
S
>E4N8Q2|squalene-hopene cyclase|EC 5.4.99.17|Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)|TrEMBL
MTATAGGRLGPQTSVAPARSDDSSPAAALSRATAHLLSLQHADGWWKGDLETNVTMDAED
LLLREFLGIRTEEQTRATAAWIRSRQREDGTWATFHGGPPELSTTVEAYVALRLAGDAPD
APHMRAAAAFVRERGGLAAARVFTRIWLALFGWWPWEKLPELPPEILFLPNWAPLNIYSF
GQWARQTIVPLTVVSAHRPVRPAPFGLAELHADPADPYPDRPLAPAHSWDGLFQRLDQLM
HRYHRHAIKPVRRLALRQAAAWIIERQEADGCWGGIQPPAVYSLIALRLMGYRLDHPVMK
AGLAAFDSFTVHTDDGKRWMEACQSPVWDTCLAAIALRDAGLPGDHPALVRAGDWMLGEE
ITTRGDWAVKRPRLAPGGWAFEFQNDTYPDVDDTAEVVLALRRIDHPDTARLAGAVERAV
DWNLGMQSKDGAWGAFDADNTSTLPNKLPFCDFGEVIDPPSADVTAHVVEMLAETGRTRD
PRTRRGVAWLLRHQEADGSWFGRWGTNYIYGTGSVLPALIAAGITPGHPAVRRAVAWLAD
RQNPDGGWGEDMRSYEDPATWAGRGESTASQTAWALMALLAAGERESEQVERGVAWLTTT
QRPDGTWDEPQFTGTGFPWDFSINYHLYRLVFPVTALGRYLHDAPLGRGGGK
>A0A533ZGG4|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
MKRLMNLITRLSGSLFSSVPDRLKGDARKRSTPALRLVSHNVHPTALPDQATRRAAGPLG
GQSESIDEAIRRSQAWLLGRQNLKDGFWVAELETDTTLTSEYLMLRRFLGLVDQERERKA
VRYLRSTQLPDGGWPIYHGGPSEISTSVKAYFALKLSGVPADEPFMVKAREAILAKGGVV
RASVFTKIALALFDQYDWRGIPCMPPEIMLLPKRFYFSIYAISYWSRTVLVPLLIMFEHR
PVCRISHEQGIEELFTQPRERIRYHEVPPLKKDRAWFTWHNLFITLDALLRLYDRMPVRR
LRERAVRKAADWTLQHVKGSGGIGAIYPAMANSVIALRCLGYELDHPVVVKALSEIEELE
VYDVVNDGQGLGETLHLQPCFSPIWDTSLLINALVEAGLPQDHPALLKAGDWLLSRQTTT
VGDWKIAAPDAEPGGWYFQFENELYPDVDDTAVVLMALGKLRMPDGAAQRQSIARGYRWV
MAMQGSDGGWGAYDKDNNRTVFNLIPFADHGALLDPSTADLAGRCLEMLGVLGYDRTHPA
AERALEFLRREQEADGSWYGRWGVNYVYGTWSVLVGLRMIGEDMSAPYVRQAVAWLESRQ
NSDGGWGESCLSYTDPAAAGRGDSTPSQTAWALLAFLSAGVWDSISVVRGVNYLIRHQQQ
DGSWEEIRQTGTGFPRVLYLRYHLYCQYFPLWALAMYRNVKTRGQMRADELCRIARETGW
FRSEV
>A0A6I7PA54|squalene-hopene cyclase|EC 5.4.99.17|Geminicoccaceae bacterium|TrEMBL
MGFALLLEPSTNELLQRVDSVVEDAATALEQRQKADGHWVFALEADATISSEYIMLEHFL
DQIDEALEADLAVYVRSLQGDHGGWPLFHGGEFNISASVKAYFALKLFGDPVDAPHMVRA
REAILAAGGAARSNVFTLYSLALFEQVPWRAVPTMPVELMLMPRWFPANMWAFSYWSRTV
IAPLLVVSALKPKARNPRRVDIRELFVTAPEAEQDYIRNPTGTRIGEAFLLLDKILKVAE
PRFSKRLRKRAIDRAVDFIVERLNGEEGVGAIFPAMANTVMAFAALGQGPDHPQRALAMR
AVQKLVTVDDQGRRFCQPCVSPVWDTALSLHALAEAGAGVDARATAWLRAKQVLDVKGDW
AVQRPDVRPGGWAFEYDNPHYPDIDDTALIGMALDRAKDPSNDEAIQRAAEWVLGLQSAN
GGWGAFDADNTRYYLNHIPFADHGALLDPPTADVTARCLGFLAQIGYDATHPAVARGLDY
LRREQEPDGSWFGRWGTNYVYGTWSVLSALNALQVPKDDPAVRRAVAYLLSQQRTDGGWG
EDGATYFADRRGEAKASTPSQTAWALMGLMAAGATAEPAVARGVRFLVDHPREGSEWEEP
WHTAVGFPRIFYLRYHGYRHVFPLWALARYRNLVRSNAGEVAYGI
>A0A077LXT3|squalene-hopene cyclase|EC 5.4.99.17|Tetrasphaera japonica T1-X7|TrEMBL
MSLLEDLTSRPGTPPDPVAVRTALDAAVALLRSVQHKDGWWKGELATNVTMDAEDLMLRH
FLGIATRRTDEETARWIRSQQADDGSWATFAGGPGELSTTVEAWVALRMAGDDPGADHLC
RAAAYVRGAGGVERARVFTHLWLSMFGLWSWDDCPSLPPEMIFLPRRAPLNIYDWACWAR
QTIVPLTIVSALRPVRPVPFDVGDLRTGATAPPRARPTSLAGVFQRLDGVLHAYARRPVG
FLRRAAMRQAAEWILARQEADGGWGGIQPPWVYSIIALHVLGYPVDHPAVRAAIAGLDGF
TICEDTPAGPVRRLEACQSPVWDTGLALAALLDCGVAPDDPAVLRATDWLLEEQIAAPGD
WQVRRPDLPSGGWAFEFANDGYPDTDDTAEIVMAMRRVAHPDAARLGRALDRAVTWTTGM
QSADGGWGAFDADNAHTLAEKLPFCDFGAVIDPSSADVTAHIVEMLATEGRAGEEACRRG
VRWLLDAQEADGSWFGRWGANHVYGTGAVVPALVAAGISPQAAPVRAAVRWLVDHQNPDG
GWGEDLRSYADPSWIGRGDSTPSQTAWALLALIAAGEDSTAVHRGIGHLLETQRPDGGWN
EDRYTGTGFPGDFYISYHLYRLVFPIWALGRYLRSRP
>A0A7V5AB36|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Acetothermia bacterium|TrEMBL
MPGVKERKDPREYLIVDRPAPSTHGRSGVEDLDEAISRAVDWLLSRQSPEGWWWAELESN
VTITAEHLFLTHILGIGSQELWEKIARYILSAQRPEGFWANWYGGPGDLSTSVEAYVALK
MAGVDPNSPPMKKAREWILSQGGVEKARVFTKIWLSMLGEWPWDATPMLPPELVLLPERF
PVNLYSFASWARGTILPLAILRVLKPVWPIPPHARIDELFARGRANADLSLPRKKSLWGR
FFYGVDKALRLYERRPLRSLRRLALKRAEEWIVERQEADGCWGGIQPPWVYSLLALYALG
YSLESPVLAKGIAGFERYSIEDERGFRLQSCISPIWDTGLALLALQDAGLPPDHPALIRA
GSWLLGEQIFVGGDWQVKCSARPGGWAFEFDNDVYPDTDDTAVVLMALLGVSLPERAKDF
ALKRGLEWLLGMQSKNGGWGAFDRNNTKTFLREIPFADFGELLDPPSEDVTAHIVELLGR
LGYRPGFEPLDRALRYLFREQKAEGPWYGRWGVNYLYGTGAVLPALRAVGFPMNDPRVRR
AVEWVLSRQNPDGGWGEDVLSYHKKELWGRGPSTASQTAWALLALLAAGEAKNPAVRRGV
EYLIRTQNDEGTWNEPYYTGTGFPTDFMIRYHLYRHVFPLMALGRYRKAVTGDK
>A0A538G5N4|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MTIAPDRTRTALDTAVERATERLLELQHPDGWWVGELESNATMIAQHLFWHHFLGLRTPE
LDRKIGNELLARQRDDGTWAIWFEGPPDLSTTIEAYTALKLAGFDPGARARDYIRSEGGV
SRARVFTKSFLALLGHWPWQWVARLPPEVILLPPDGPFSVYNFSCWARQTVVPLSVVQAL
RPVRAARIDLREIGARAGQTKPPPRPGPIRRVAFATAERWVRDRQEADGSWGGIQPPWVW
SIIMLAALGYGFEDETLRAAVEGWQGFTIDEGDRLRPEACQSPVWDTALAAIALLEAGLS
PTHPALRRAGEWLVEEEVAARGDWAIRRPDLPPGGWAFEFENDLYPDVDDTAVVALALGR
LGLGADAVERGLAWTAGMQSRSGGWGAFDVDNEAHWLYKLPFCDFGKVTDEPSADVSAHA
LEALAPESRYAEEVERGLAWLLAEQERDGSWFGRWGVNHIYGTGAALPALEACEVPSGHP
AMQRAVEWLRSVQQPDGSFGEDIRSYADAGSRGRGHPTPSQTAWALLGYVAAGEADSDSA
KRAADWLCSEQLSNGDWQEDHYTGTGFPLDFMIRYHLYRLHFPLMALGRLRERLAA
>A0A537W273|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MASSTVDARSEAGVALKLACEHLLSLQDDAGWWRGELQTNVTMDAEDILLREFLGVRRAD
ETRRSAAWIRSQQRDDGTWANFHGAAGDLSTTIEAYWALRLAGDPAEAQHMLAAAEFIRR
EGGLERARVFTHLWLALFGLWSWDRVPALPAEAILLPSWVPLNVYDFACWARQTIVALSV
VKAHRPVRPLQFGLEELHTATQGPRPERSISRRGAWLARLDRVLRAYERHPFAPLRRLAL
GRAERWIVRRQEADGSWGGIQPPWVYSLIALDLAGYPLEHPVMRRGLEGLSAFTVEDYDD
AHGVGAPPGPSRRLEACQSPVWDTALAMVALSDGGLAPEHPAMRRAGEWLLGEEVTVRGD
WAVKRPGVTPGGWAFEFANVNYPDVDDTAEVVLALRRVAGGGADAAAEPAASVNGAEAGE
ASPEAGLARRIDGALARALEWIEGMQSSDGGWGAFDADNTRGLVRELPFLDFGEVIDEPS
ADVTAHTVEMLGELGLAESSAARRGVRWLLEHQERDGSWFGRWGVNHIYGTGAAIPALLV
AGVDPSHGCVRRAVAWLERIQNEDGGWGEDPRSYDDPQWIGRGPSTASQTAWALLALHAA
GECSAAVERGIAWLVATQRADGGWEEPQYTGTGFPSDYYINYHLYRLTFPIMALGRCLAA
SDDGADAMSEGASGQKG
>A0A551Z7Z1|squalene-hopene cyclase|EC 5.4.99.17|Microcystis sp. M_QC_C_20170808_M3Col|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSDGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDLALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKIGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKAVDNFAIE
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKSVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVKMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRHQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLITQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A7Y0PQT0|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetospora sp. TBRC 11914|TrEMBL
MTLSVPATDTTTRTTRTVEEALDAGIAHLRSRQDAAGWWKGDLDTNVTMDAEDLLLRHVL
EISDPERTAGAARWIRSQQRADGTWATFAGGPGDLSTTAEAWVALRLAGDHPGAPHMLSA
AEFVREQGGVERTRVFTRVWLALVGLWSWDDLPAMPPELIHLPRWFPLNVSDWACWARQT
VVPLTVVSTLRPSHPVDFDIAELRTGAAPAAFDPVWTWSGFFSRLDVGLHAYARAARRGP
LAWIRRGAMRKAGEWILARQEADGGWGGIQPPWVYSLMALVLLGYPREHPSVVAAIRGLD
GFTLTTDSPDGPVIRLEACQSPVWDTCLAVNALHDARVPADDPAVVAGTRWLLDEQVTLT
GDWAVQRPTLAPGGWSFEFANDVYPDTDDTAEVVLALRRSEHAGLSEAERAELRHAVDRG
LDWAAGMVSADGGWGAFDADNTRELVNKLPFCDFGEVIDPPSADVTAHVVEALASEGRSG
TVECRRGVRWLLGAQEADGSWFGRWGANHLYGTGGVVPALVAAGIDPGSTPIRRAVRWLH
DHQNDDGGWGEDLRSYVDPAWIGRGASTPSQTAWALLALIAAGDRSAATERGVRWLVDAQ
RPDGGWDEEQFTGTGFPGDFYIAYHLYRVVFPISALGRWVHGWDGVA
>A0A6B3BJF5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID12501|TrEMBL
MTATTDGSTGALPPPAASASETDTDTNTPAAAGVQDAAERAMRRAADSLLARQDAQGWWK
GDLETNVTMDAEDLLLRQFLGIRDEQTTQAAALFIRGEQRDDGTWATFFGGPADLSATVE
AYVALRMAGDAPEAPHMAKASAFVRDRGGIAAARVFTRIWLALFGWWKWDDLPELPPELI
YFPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHIDPDLPNPGKSFAPLA
SWDGAFQRLDRVLHGYRKVAVRRLRKAAMNAAARWIIERQENDGCWGGIQPPAVYSVIAL
HLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLAVIALADAGLPADHP
QLVKAADWMLGEQVVRPGDWSVRRPELPPGGWAFEFHNDNYPDMDDTAEVVLALRRVRHH
DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSTLPNKLPFCDFGEVIDPPSADVTAH
VVEMLAVEGMSHDPRTRRGIEWLLAEQEPGGAWFGRWGVNYVYGTGSVVPALTAAGLPTV
HPAIRRAVGWLEKVQNDDGGWGEDLRSYEDSAVWSGRGASTASQTAWALLALLAAGEHDS
KAVERGVEWLAATQLPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPFA
EAKEG
>W6K6A9|squalene-hopene cyclase|EC 5.4.99.17|Magnetospira sp. (strain QH-2)|TrEMBL
MNHTSDTSEDLKAVDRLVGEAADWLVDLQEADGHLVFELEADATIPAEYILLNHFLGEPN
DKLERKIAVYLRRIQNDEGGWPLFHEGDTDISASVKAYFALKIVGDDPEAPHMVKARQLI
LGMGGAAKSNVFTRIMLAQFEQIPWRGIPFIPIEVILLPEWFPFHMDKVSYWSRTVMMPL
LVLYALHAKARHPRKVHIRELFVTPPEKEKRYNVNPTGHWVGEALLVADKYARRMSFLIP
KSWKRKAIDKAMTFIRERINGENGLGAIFPAMANSVMAMDALGYQRDHPDYVVARKSIDN
LLVCKETETYCQPCVSPVWDTSLAAHALMEAGRDEAAHAALDWLQGRQVLHVNGDWTARR
PDVRPGGWAFQYWNDYYPDVDDTAVVGMALDRQGDPKYIENIDRAVEWIVGMQSSNGGWG
AFDAENEHYFLNHIPFADHGALLDPPTEDVTARCLGFLAQVGYGKDHPAVQAALDYLYRE
QLDDGSWFGRWGSNYIYGTWSVLNALNGVGEDMDSEAVRRAVDWLKSRQQADGGWGESCS
SYYDAREAEDSVPTPSHTSWALLGLMAAGEVNSEAVRRGIRWLSQAPRDGGKWHEELYNA
PGFPRVFYLHYHGYSAYFPLWALARYRNLVSGNAHRPLYGM
>G4NQ27|squalene-hopene cyclase|EC 5.4.99.17|Bacillus spizizenii (strain DSM 15029 / JCM 12233 / NBRC 101239 / NRRL B-23049 / TU-B-10)|TrEMBL
MGTLQEKVRRYQKKTIAELKDRQNADGSWTFCFEGPIMTNSFFILLLTSLDEGENEKELI
SALAAGIREKQQPDGTFINYPDETSGNITATVQGYVGMLASGCFHRSDPHMRKAEQFIIS
HGGLRHVHFMTKWMLAVNGLYPWPVLYLPLSLMALPPTLPVHFYQFSAYARIHFAPMAVT
LNQRFVLNNRNIPSLRHLDPHMTNNPFTWLRSDAFEERDLTSIWSHWKRIFHAPFAFQQL
GLQTAKTYMLDRLEKDGTLYSYASATIFMVYSLLSLGVSRYSPVIRRAINGIKSLMTKCN
GIPYLENSTSTVWDTALISYALQKNGVTETDGSITKAAAYLLERQHTKIADWSVKNPSAA
PGGWGFSNINTNNPDCDDTAAVLKAIPRSYSPSAWERGVSWLLSMQNNDGGFSAFEKNVN
HPLIRLLPLESAEDAAVDPSTADLTGRVLHFLGEKAGFTVKHQHIQRAVGWLLEHQEQNG
SWYGRWGVCYIYGTWAALTGMHACGVDRKHPAIQKALRWLKSIQHDDGSWGESCKSAEVK
TYVPLHKGTIVQTAWALDALLTYENSEHPSVVKGMQYLTDSSSHGADSLAYPAGIGLPNQ
FYILYHSYPYVFSLLAVGKYLNFIEKETANET
>A0A850SG63|squalene-hopene cyclase|EC 5.4.99.17|Parvularculaceae bacterium|TrEMBL
MFDEKTGGKARGNFEAALDRSIDSAADWLARKQKPEGYWVGRLESNACMEAQWLLALWVM
RLDDHHLRPRLARSLRQSQRADGSWEIYHEAPAGDINTTVEAYAALRSMGVPASDPQLVR
ARDWILSKGGLKNIRVFTRYWLALIGEWPWEKTPNVPPEVIWFPNWFVFSIYNFAQWARA
TLMPIAILSARRPSRPLPPANRLDDLFPGGREAFDYELPGKPGADFCDGFFRTVDRALHG
LHGFGVKTGLSLGRGAAIRHALEWIIKHQDADGVWGGIQPPWIYSLLALYTEGYAHDHPV
LAKGLAALDDPRWRVDVGEATWIQASTSPVWDTELALMAFDDAHLLDRYPAAVDKGVQWL
LDQQVRRPGEWQVKVPKVAPGGWAFEYKNYFYPDTDDTAVALIILSQFRNDPKWKARGID
EAIRLGVDWLTAMQCRGGGWGAFDKDNDKKILTKIPFCDFGEALDPPSVDVTAHIIEAFG
KLGHDQNHPVMQRAIAWTLKEQEPDGSWFGRWGVNYIYGTGAVLPALAAVGFDMTRPEIH
RACDWLVDRQQADGGWGESCASYMDASMSGRGKTTASQTAWALMGLVAAARPQDRGAIER
GLAFLIERQKEGTWEEPEYTGTGFPGYGVGQTIKLSDPLLKERLKQGPELSRAFMINYNL
YRHYFPLMAMGRARRMLHR
>A0A7H0EZ56|squalene-hopene cyclase|EC 5.4.99.17|Cylindrospermopsis curvispora GIHE-G1|TrEMBL
MQTQPRINIKEITQAIAASQEHLLSIQRPEGYWWGELESNVTITVEVLLLHKIWGTCENR
ALYKIENYLRCQQREHGGWELYYGDGGDLSTSVEAYMGLRLLGVPATDTALVKAKSWILK
KGGISKTRIFTKLHLALIGCYNWRGLPSLPPWVMLLPDYFPFNIYELSSWARSSTVPLLI
VFNRKPVFDIDSPISLDELYAEGIDNAQWELPKNNDWSDIFTLLDDGFKLAETLNLVPLR
DQGIKAAEKWILERQESTGDWGGIIPAMLNSLLALKCLNYKADDPIIYGGLKAVDNFVIE
TDNSYCVQPCVSPVWDTAWAIRALIDSGMAPDDPVIVKAGEWLIDKQIIDYGDWAVKNKQ
GQPGAWAFEFHNRFYPDVDDSAVVVMALHQAKLPNENLKKQAIKRAVNWIISMQCKSGGW
AAFDIDNDQEWLNYIPYGDLKAMIDPNTADVTARVIEMLGVCKLSIPSQKLDQAMNYLLG
EQETEGCWFGRWGVNYIYGTSGVLSALALINPQKYLSNIEKGANWLKQVQNPDGGWGETC
LSYGDPNFKGKGDSTPSQTAWGLMGLIAAGEARQNFDLTTMEKAVNYLLTTQRLDGTWDE
SYFTGTGFPGHFYLKYHLYQQYFPLLALGRYRRIVNSTWP
>A0A7Z9LLH1|squalene-hopene cyclase|EC 5.4.99.17|Methylococcaceae bacterium|TrEMBL
MYTESFNEKNDLEAISVSARKAFNLDSAINAAQAELTNLQNDQGYWHFELEADCSITAEY
ILMMHYFGEENDSLQEQMATYLRARQTENGSYSLFTGGTDDLSCSVKVYFALKLAGDQTT
SPHMVKLKNYILAQGGAAKSNVFTRITLAIFEQIPWRGVPYIPVEIMLLPKWFPFHLDRV
SYWSRTVMVPLFILCTLKAKALNPKRINITELFVTPPDEEQHYFSNDTLLSKIFLGLDKL
GLITRPFIPKRLTQKSFDLALAWIIERLNGEDGLGGIFPAMVSAYQAMLLLEIPIDHPQV
KTARQAIDKLVVFRDQEAYCQPCLSPVWDTGLAALALQEADPEGTRPHREKAYNWLKSKQ
LHKQPGDWQIRQPHLEGGGWAFQFENPHYPDVDDTALIAFAMANADLPNLNESINRATRW
TAGMQSKNGGFGAFDCDNTDYYLNHIPFADHGALLDPPTADVSARCAMLLGHQIKNHPEY
QTTLDDTIAYLRSEQEADGSWFGRWGTNYVYGTWSVLLGLEQTQVPRNDPMYTTAVKWLK
SVQNSDGGWGEDNHSYHDDSTRGQDESSTCFQTAWALLGLMAAGEVNSPEVKNGINYILA
HQTEEGLWVDSGFTAPGFPKVFYLKYYGYDKFFPLWALARYRNELKKL
>A0A800GM19|squalene-hopene cyclase|EC 5.4.99.17|Methylococcaceae bacterium|TrEMBL
MFNEPANNNDDALNRPFSSKQHSNTLDSAIQSAQDKLLSLQDQEGFWVFELEADCCIPAE
YIMMMHYLDDIDEELQNKIANYLRSRQSTEGHYPLFTEGVGDISSSIKSYYALKMAGDSI
DAPHMKKNREYILSQGGAAKANVFTRIALAMFEQLPWRGVPYIPVEIMLLPKWFPFHLDK
VSYWSRAVMVPLFILCTFKATAKNPHKVGIRELFLIDPDKEQHYFPERTFLNKCFLAMDK
LGRMTRRFYPKKMTQYAVDQAVAWFTERLNGEDGLGGISPAMIYAYEAMLLLDYPKDHPQ
VVTARKAIDKLLVINEHDAYCQPCLSPVWDTGLAVLALQEADKQANKESLSRAYDWLKSK
QLSDEPGDWRIARPDVDGGGWAFQFENPHYPDVDDTALIAFAMADSNFTDMEEPIHRATR
WIVGMQSKNGGYGAFDVDNTYYYLNEIPFADHGALLDPPSADVSARCAMLMAKVAKNHAE
YLPALARTIEYIRTEQEEDGSWFGRWGTNYIYGTWSVLLGLEQTDIPKTDPLYTKAVSYL
KSVQREDGGWGEDNKSYYDIKQYSGQYHFSTSFQTAWAVLGLLSAGEGNSPEVKAGIDFI
LSQQQADGVWDDKCFTAPGFPKVFFLKYHGYDKFFPLWALARYRNELTRLN
>A0A7D4A2I3|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura verrucosospora|TrEMBL
MTATEPTETTGTATAGTAESTAVRTPAEAMAAARDHLLGLQSPEGWWKGELQTNVTMDAE
DLLMREFLGIRTAEDTREAARWIRSQQAPDGTWANFHDGPPDLSTTVEAYVALRLAGDEP
DAPHMRRAAAFVRGEGGIPATRVFTRFWLAMFGQWPWERLPALPPEMVFLPHWFPLNVYD
FACWARQTIVPLTVVAAKRPVRPLPFELEELRSGRVVRRRRGAVPGWDEAFAALDRVLRG
YERRPLRGLRKAALRRAAEWIIARQEPDGSWGGIQPPWVYSLLALHLLGHGLDHPVVRRG
LEGLERFTVRDEKGRRLEACQSPVWDTVLAMNALVDAGLPAGHQALEAAAEWVVGEEVQG
PGDWSVRRPDLPPGGWAFEFDNDYYPDTDDTAEVVLALSRVDHPKAEPAIERGVRWMAGM
VSRDGGFGAFDADNTRALCRRLPFCDFGEVIDPPSADVTAHVVEALSLRGMADSTLVKRA
VVWLLKAQEDDGSWFGRWGANHVYGTGSVVPALIAAGVRPEKPAIRRAVRWLERHQRDDG
GWGEDLRSYRDPEWVGHGVSTASQTAWALLALLAAGERGPAVERGVRWLVEHQRPDGTWD
EDHFTGTGFPGDFYINYHLYRLVFPLSALGRYVKEIGS
>A0A5N9BWK3|squalene-hopene cyclase|EC 5.4.99.17|SAR202 cluster bacterium|TrEMBL
METLDSQQFNKDLKTAIKRTQDYLFKEQYSEGFWWGELESNPTMEAEFLLLHYFLGIRDE
EKFVKLSNHIKSQQRDDGTWGQYYGAPGDLSTSVECYLALKIAGYSETAPSMIKAKDFIV
SKGGIEKTRVFTKIWLSLVDQWKWKGVPIMPAELILLPNWSPINIYEFSSWARSTIVPLL
ILMDKKPVQPLPANLRVDELFCNGADNVDYSVKSPSNQIGWETFFYATDQVLRLLDKLPI
KPTRDLALKKSEQWILEHQEADGSWGGIQPPWVYSIMALYAAGYELDHPVIAKALNGFKA
FAIEDEHSLRVQACVSPIWDTGLAIISLLDSGIKADDDRVQKAGQWLINKQIKSDGDWQI
KANNVRSGGWAFEFENEHYPDIDDAAVVATALHKIALTDEYGGLDRKSKSIKRCVQWIEG
MQSKNGGWASFDKDNMRSFIARIPFSDFGETIDPPSVDVTAHVLELLGTLDAKKYDQVIK
KALDYVLLEQEQDGSWFGRWGVNYIYGIGSVLPALRAIGIDPSHEAMIKATRWLEEHQNE
DGGWGETPASYVDPSLHGKGPSTASQTAWSLISLIAADKGDSPEVLQGVNYLLSTQNEDG
SWDEPEFTGTGFPGYGIGMRPDISEKDNSKDQDIALPAGFMINYHMYRIYWPLCALGRFK
SWSINSGRHISLK
>A0A5N9BPU9|squalene-hopene cyclase|EC 5.4.99.17|SAR202 cluster bacterium|TrEMBL
MVRRARLCGREEPKSGDATTVAQLKHSDVNQAADEAVQRSQDYFRRTQYPEGYWWGELES
NPTMEAEYLMLCHFTGRHDQERWRKICNYILSKQRSDGSWSQYYEAPGDVSTSVECYFAL
KLAGHSPDTEPLRKAREFILSKGGIPKVRVFTKIWLALFGQWDWKGTPNMPPEMIFLPSW
APFNIYEFASWARATVVPMLIILTRQPYCAVPESADIGELYPGGREGTDYHLPKPTGGFG
WSKALYWADKLVGLYQRLPVHPFRGRAERKIIQWVLDHQEADGSWAGIQPPWVYSLITLH
TLGYGPDHEAVKKGFQGFERFALEDEDKCNVQACISPVWDTCIAQLALLESGIDPEDPMV
QSSARWLMDKQIYATADWQVRAKGTRPGGWSFEFDNLIYPDVDDASIVVMALDQVRLPEA
EEPRRADSIQRGVEWMAGMQSKNGGWAAFDKDNNKKYLTKIPFSDFGETLDPPSVDVTAH
LLEMYGRLGYTKENRAVDRGFAYVVSEQEEDGSWFGRWGVNYVYGIGAVLPALEAIGEDM
SQAYIRLAVDWTVAHQNQDGGWGESCGSYVDPNLHGVGPSTASQTAWALLGLVAAGEHES
EAAQRGLVYLAETQLEDGTWDEPYFTGTGFPGYGVGERLKAMPDIGETSYQGLDMPAGFM
INYHLYRNYWPLLALGRYSQAVSGRL
>A0A850NYJ5|squalene-hopene cyclase|EC 5.4.99.17|Komagataeibacter swingsii|TrEMBL
MENMTRESRPLTKTAASSGNITSGNTFPAAGTQSVNGGGKSTGSASALRTMDNSLSHAIS
SACDWLVGQQKPDGHWVGPVASNASMEAEWCLALWFLGLDDHPLRPRLGKALLEMQREDG
SWGTYYGAGNGDINATVESYAALRSLGYPADDPAISRAATWIASKGGLKNIRVFTRYWLA
LIGEWPWEKTPNLPPEVIWFPNNFVFSIYNFAQWARATLVPLAILSARRPSRPLRPQDRL
DALFPGGRANFDYELPARGDRDLWGRFFRATDRGLHWLQSRFLKRNTLREAAIRHMLEWI
IRHQDADGGWGGIQPPWVYGLMALHGEDYQFHHPVMAKALSALNDPGWRHDRGDASWIQA
TNSPVWDTMLAIMALHDADGETQFSPQMEKALGWLLDRQVRVKGDWSIKLPDVEPGGWAF
EYANDRYPDTDDTAVALIALSSCRNREEWKKRGVEEAISRGVNWLIGMQSECGGWGAFDK
DNNRSILSKIPFCDFGEALDPPSVDVTAHVLEAFGILGLPRHMPTIQRALAYIRAEQEPD
GPWFGRWGVNYLYGTGAVLPALAAIGEDMKQPYITKACDWLVAHQQENGGWGESCASYME
LSMVGRGVTTPSQTAWALMGLIAANRPQDYGAIARGCRYLIDLQQADGSWHEKEFTGTGF
PGYGVGQTIKLDDPALSKRLQQGAELSRAFMLRYDLYRQFFPIMALSRASRLMKLEK
>A0A6I4MBP7|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura physcomitrii|TrEMBL
MTTTEAPGLTEAAAAAVEAARDHLLGLQSAEGWWKAELETNVTMDAEDLLLRQFLGIRTE
AETAAAARWIRSQQRADGTWANFYEGPPDPSTTIEAYVALRLAGDAPDAEHMRKAAAYAR
EAGGIEGSRVFTRIWLALFGQWSWDDLPVMPPELMFLPSRVPLNVYSWACWARQTIVPLT
VLGSLRPVRALPFDLAELRAGRRPARKATGWGAAFNALDRALHVYEKRPVRPLRRAALRR
AAEWIVARQEADGCWGGIQPPWVYSLMALSLLGYDLDHPVMKRGLAGLDRFTIEDEKGRR
LEACQSPVWDTVLAMNALSDAGAPEGDPALLRAARWVVNEEIRGPGDWSVRRPDLPPGGW
AFEFDNDLYPDTDDTAEAILALRRSGLPDARGPIDRAVRWMAGMASKDGGFAAFDADNTQ
ELCTKLPFCDFGAVIDPPSADVTAHVVEALAKEGHAESPVTKRAVVWLLKAQETDGSWFG
RWGANHVYGTGGVVPALIAAGVRPDKPPIRRAVAWLEQHQNPDGGWGEDLRSYDDPSWIG
RGTSTPSQTAWALLALLAAGERSPAVEAGVRWLVEHQRPDGTWDEDQFTGTGFPGDFYIN
YHLYRLVFPISALGRYLGRDR
>A0A0T6A5C0|squalene-hopene cyclase|EC 5.4.99.17|candidate division NC10 bacterium CSP1-5|TrEMBL
MAPPSIEESRTVQRVEEAIGRAQEHLLSLQHPEGYWLGELEADSTLTSEYIMLRHFLRRV
DRDRERKVANYLKARQLPDGGWDLFPGGASDISATVKAYFAFKLMGYSPDDAFMRRAREN
IVAKGGVTKANVFTKIALALFGQYDWRGVPSMPVEIILFPRWFYFNLAEVSYWSRTVIVP
LLILMDLKPVCRIPAAAGIDELYVPSRAAADLRFPRSERLFTWKNFFITLDRLLHGLERW
TPRPFRARARQQALTWILTRMGPGGLGGIYPAMANAVMALHTLGYSEDHPKMAEGLKEIE
LLGIEEADRFHLQPCLSPVWDTPLAVNALVESALPRDHPALLRAATWLLQQQSLRRGDWQ
VKRPELPPGGWPFQFRNDFYPDTDDTAVVLMALKKIALPDRADIRQAIETGLEWFLGMQS
RNGGWGSFDVDNTRLLLNNIPFADHGALLDPPTEDLAGRGLEMLGTYEETLAHPRAARAL
DFVKRTQDPRGGWYGRWGANYIYGTWSVLRGLQAIGEDLNASYIRRAVRWLESCQNADGG
WGETLLSYADPTLAGKGESIPSQTAWALLGLLAAGEAQNPAVARGIRFLIETQRSDGSWD
DPFWNATGFPRVFFLKYHLYPVYFPLWALGVYRTALQRSL
>A0A534E3S0|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MSRKAGTSAALAGTEGLLRADAPARKLPGEKLSPLEYAIAAARDELIRLQRPDGSWQLEL
EADCTIPAEYIMMMHFLGELDAALEAKLAAYLRQRQAGYGGWPLYHGGAFDMSCSVKVYF
ALKLAGDDPESPHMARARAAILERGGAASCNVFTRIALALFGQLPWRGVPYIPVEIVLLP
CWFPFNIHRVSYWSRTVMVPLLILCTLKPRARNPRNVDIRELFTTPPSQERRYFRRPLGG
SAALARAFFCLDRLARSLDGFIPRALREHALERAEAWMLERLNGEEGLGAIFPAMVNALE
ALSVRGYSPDHPHRRGAKRALEKLLVEDYSSAYCQPCASTLWDTALASLAMQEEGSAGAR
AAALRGLEWLEPRQLLDDPGDWRTRRPHLPGGGWAFQRANSYYPDLDDTAAVAWSMHRST
DPGRFSFALSRALDWLVGMQSENGGFASFDVDNTSYYLNEIPFADHGALLDPPTSDVTAR
VVTALARVGRPEDRGALTRAIDYLRREQEANGSWFGRWGTNYVYGTWSVLSAFAEARIGP
DDPAVERAVSWLESRQNPDGGWGESNDSYEPGRAGASAPSTPHQSAWAVLALIAAREAGS
DAVRRGIEYLLRTQRPDGLWSDPSFTAPGFPRVFYLRYHGYCAYFPLWALAAYRNSTAAG
PGTVH
>A0A3R9UY34|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. WAC08401|TrEMBL
MTATTDGSTGATLRPLAAAASENEITTPDTAAGVPEAAARATRRATDFLLSRQDAQGWWK
GDLETNVTMDAEDLLLRQFLGILDEETTRAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDAPDAPHMARASEWIRSRGGIAASRVFTRIWLALFGWWKWDDLPELPPEII
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAVPNPPRPLAPAA
SWDGAFQRIDKALHAYRRIAPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHP
QLVKAADWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHH
DPERVEQAIGRGVRWNLGMQSKNGAWGAFDVDNTSSFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAVEGLTHDPRTRRGIQWLLAEQEADGSWFGRWGVNYVYGTGSVVPALIAAGVPAS
HPAVRRAVAWLESVQNDDGGWGEDLRSYRYVREWSGRGASTASQTAWALMALLAAGERES
KAVERGIAWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFA
QKSGAARPATETSTAEVKGS
>A0A3B7QFS2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces fradiae|TrEMBL
MTATTDGSTGAVTPRAASASHSIDTPAATAPTAGTREAAALAIQRSTDFLLSRQDAEGWW
KGDLETNVTMDAEDLLLRQFLGIGDERTTRAAALFIRGEQREDGTWATFFGGPGELSTTI
EAYVALRLAGDLPDAPHMARAAEWIRDRGGIAESRVFTRIWLALFGWWSWDDLPELPPEL
IYFPPWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHVDARVPRPPKPLAPA
TSWDGLFERLDKALHVYHKVAPRRLRGAAMNSAARWIIERQENDGCWGGIQPPAVYSIIA
LHLLGYDLEHPVLKAGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADH
PQLVRAADWMLGEEIVRPGDWAVRKPRLAPGGWAFEFHNDNYPDIDDTAEVALALRRVAH
PDQARVDNAIARGMRWTLGMQSKNGAWAAFDADNTSPFPNRLPFCDFGEVIDPPSADVTG
HVVEMLAVEGRSHDPRTRRGIEWLLAEQEDNGAWFGRWGVNYLYGTGSVVPALITAGLPA
SHAAIRRAVRWVESVQNDDGGWGEDLRSYRDRGWVGHGTSTASQTAWALLALLSAGERDA
PSVERGIAWLAATQRPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPFP
AGSAHAGKGS
>A0A3A5AJB4|squalene-hopene cyclase|EC 5.4.99.17|Desulfobacteraceae bacterium|TrEMBL
MRRLHCSPGLSASYANPVERQDLEKIESYPPGATSLIEPARAALFSVERLNDVISRARNS
ILSLQQKKGYWVFDLEADCTIPAEYIILQRFLRKSIPRERAELFSNYLRRRQIPKGGWPV
FQGGAAEISASTKVYFALKLLGDSPEEGHMKDARRTILRLGGASRVNVFTRITLALFGQI
PWRTVPAMPVEIMLLPRWFFFHISKISYWSRTVMIPLLILFNKKPVCPLRPEEGLHELFL
EPPNELVTLDRFVPGNGRKNLFICLDRLLKRIDRFAPRRTREKALYKAAEWTLDRMRGRG
GLGAIFPAMVNSVMALKVLGFTEDQPEFVRGIAALDDLLVKKGDEEFCQPCVSPVWDTCL
SLSSILEEGVPPEDAAVTSSVEWLFENQILTGGDWCMKAPRVDPGGWAFQFENTLYPDVD
DTPAVLMSIIRAGCLKDKNYSERIAKAVQWVLGMQSSDGGWGSFDIDNNCLHLNEIPFAD
HGALLDPSTSDLTGRCLELLSMVGFGRDFPPVARALRFLRKEQEPCGAWFGRWGVNYLYG
TWSVLMGLKQAGEDMRLPYIRRAVEWVKSCQNGDYGWGESCYTYEEPSLAGLGRSTASQT
AWALLALMAAGEHRSSAVQGGIHYLLNSQNAQGGWDEDLFTGTGFPRVFYLRYHGYSRYF
PLWALSVYRRLRSGKKTRQEEVSCRGLWTRMG
>A0A5R8Z6V9|squalene-hopene cyclase|EC 5.4.99.17|Microbispora fusca|TrEMBL
MTALLTAASRAATALEAARDHLLALQSPEGWWKGELRTNVTMDAEDLLLREFLGVRTAAE
TAGAARWIRSQQQAGGGWANFHDGPADLSTTVEAYTALRLAGDPPSAPHLRAAAALVRDL
GGVESTRVFTRIWLAMFGQWRWEDLPVIPPEIVFLPPWCPLNVYDWACWARQTIVPLTIV
TAHRPVRPLPFGLAELRTGRPARRGPRTGWDAAFAALDHVLHRYERRPLAGLRRAALRRA
AEWVVARQEADGSWGGIQPPWVYSLIALRLSGYDVSHPVMRRGLAGLDRFTIREDGSRRL
EACQSPVWDTALAVIALLDAGLPRDHPALDRAGEWLLREEIRGPGDWAVRRPGLTPGGWA
FEFDNDGYPDVDDTAEVILALGRWGRPAARDAVRRGLRWTAGMASRDGGFAAFDADNTRA
LCLRLPFCDFGAVIDPPSADVTAHVVEALAAEGLARSPVVRRAVTWLLRAQEPGGSWFGR
WGANHVYGTGAVLPALAAAGVPPAAPCVRRAVAWLEAHQHPGGGWGEDMRSYRDPAWIGR
GEPTASQTAWALIGLLAAGERGPSVERGVAWLAGTQRPDGTWDEPHYTGTGFPGDFFINY
HLYRLVFPVSALGRYLRAGKGGTP
>A0A4R5LYF0|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia silviterrae|TrEMBL
MKNSDLPTNLQRAALLDAAIVRGRDALARRQQPDGSWCFELESDATITAEYILMMHFMGK
IDTVRQEKMARYLRAIQRLETHGAWDLYVDGAPDVSASVKAYFALKAAGDAQSAPHMVRA
REAILKLGGAAKSNVFTRILLATFGQVPWRATPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLALCSLKAQARNPHNVSIAELFVTPAQEEREYFPRGKGVRKLFLALDRTVRHLEPL
IPRALRARAMKHAEAWCAERMNGEDGMGGIFPPIVYSYQMMEVLGYHENHPLRRDCENAL
EKLLVERPDGSMYCQPCLSPVWDTAWSTMALEQAVAVPEMLGVDTPGTESTPNAELQQKI
ARAYDWLATRQVDDLKGDWIENVSPDVPPGGWAFQYANPYYPDIDDSAVVAAMLHRRGRS
LKRTTGTDPYAARVTRALDWIRGLQSRNGGFAAFDADCDRLYLNAIPFADHGALLDPPTE
DVSGRVLLCFGVTGREEDKAALVRTIEYIKATQQADGSWWGRWGTNYIYGTWSVLAGLAL
AGEDPSQPYIARALAWLRSRQHADGGWGETNDSYIDPRLAGTNGGESTSNFTAWALLAQM
AFGDYESESVRRGIAYLLSVQDGEGFWWHRSHNAPGFPRIYYLKYHGYTAYFPLWALARY
RRLAADAARVSEAKADEAVMLA
>A0A6I4Z1T9|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
MTAPSSLQQDPARAGSGVDASGLDVCIDRSVKHLLSLQAEDGYWWAELESNATMAAEHLL
LERFLGTTEEEREQGIVRYLLGLQTEDGSWPVYWGGPGDVSITTEAYFALKLAGVDPERD
EMKRAREFIRDKGGVGATRIFTKLWLALFGQFEWSALPAMPPESILMPVSSPLNIYMFAS
WARATIVAILVVWAYRPVVPIPEYAHVDELYLDPMDRRSIPLRRDRQPFTWRNAFLAIDR
VLHAHERLPWKPLRQYALKECERWIIEHQEADGTWGVIQPPSVYSLIALRAHGYSMDDPV
MKKGLNGFLGDFALRRGNTFSVQPCLSPVWDTALAVTGLREAGVPADDEALVQAGRWMLA
HEVQSLGDWALTVPGIEPGGFPFEFSNELYPDTDDTAEVLIALRLVDVRGKDGPFHRAKR
WLRAMQSTNGGWGAFDRDNNDEFVSRIPFADFGATFDPPTEDVTAHIVEAFALEGTPPSD
EMIEQALGYLWDTQEPDGSWWGRWGVNYLYGLGAAVPALVAAGVDPADPRLQRAVRWLEH
HQQPDGGWGESCATYEDPSLRGQGPSTASQTAWALLALLALEPPDHPAIVRGIDYLVRTQ
TDDGEWHEPHFTGTGFPRDFMLKYHLYCNYWPLWALGRYRRLRDGNPIHLPDTDPLA
>A0A6I4ZQ88|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
MIEQGMENRLREALERTQRYFFRTQHEDGYWWGELESNPTMEAEYIMLTHFLGSEEEDRI
PRIAEDIRRRQSADGSWRMYYGAPGDLSTSIECYFALKLAGDPPEAPHMAKARTFILACG
GVPKARVFTKIWLALFGQWDWKGTPAMPPDMMLLPRWAPFNIYRFASWARATIVPMTIIL
TLHPTRPPHESAWVTELYPEGPVTFTLSRWKAKPFSLKGWFLVLDRAIRIYRKLPFIPGR
KRAIKAAVDWIVRHQEADGSWAGIQPPWVYSLIALSAIGFPLDDPVISKGLEGFRRNWSV
PSEDGDALRVQACLSPVWDTCLAMRGLFDSGVPANHPAIRGAAAWLIQEEIRVKGDWAVY
RPHLEPSGWAFEFNNVHYPDIDDSAIVVTDLAATRMRDDTGERARTEALDRAVNWLTGMQ
CSNGGWAAFDWNNDSRELAKIPFADFGELLDPPSVDVTAHVLEMYAKLGYTVEHPAVRRG
LSYIWEQQEHDGPWFGRWGVNYIYGTGAVLPALEALDLDMRQPRVRRAVKWLLARQNPDG
GWGETCVSYADPSLRGQGESTPSQTSWALMALIAAGEAGHEYVARGVEFLLERQQEDGTW
DEPQFTGCGFPGYGPGERPNEYEPLDGPNSQGPELGAAFMIKYHLYRNYFPLSALGRYAQ
SLHP
>I4G2V7|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa PCC 9443|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRRQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPANDPTLEKAREFI
LAQGGISKTRIFTKMHLALIGCYDWLGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGLNNVKYELPKSNNWSDVFLWLDGLFKWAEKTNLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALDYDVDDPIVARGLKAVDNFAIQ
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAIIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKGVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVKMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSGCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A4R4QMD8|squalene-hopene cyclase|EC 5.4.99.17|Micromonospora sp. 15K316|TrEMBL
MTELLSAKTTTVDPGPPAGPDPLDSAREALHRAREHLLGLQDDAGWWKGELATNVTMDAE
DLLLRQFLGIRTAEQTEETARWIRSQQLPDGSWATFHGGPGDLSTTIEAYVALRLAGDTV
EAPHMTAAAAFVRAHGGLAASRVFTRFWLAMFGHWPWSRLPAVPPELVLLPSWVPFNVYD
FACWARQTIVPLSIVRALRPVRSLGFGVDELRTSDRPPRPPRLTSRPGLLHRLDRLAGSY
ERIARGPVRRHALRRAAEWIVARQEADGSWGGIQPPWVYSLMALHLLGYPLDHPVLRAGL
EGLERFTVRTRTPDGPMRWLEACQSPVWDTALAVTALADAGLPAGHPALERAGRWLLDEE
VRVRGDWAVRRPNTPPGGWAFEFDNDGYADTDDTAEVIIALRRAGVPADAAVLRATRWML
GMQCRDGGWAAFDADNTRAILADLPFCDFGEVIDPPSADVTAHVVEALVAENYAGTMPVR
RGVHWLLRAQEPDGSWFGRWGANHVYGTGAVVPALVAAGVPRRHPAIRRAVEWLLAHQGA
DGGWGEDLRSYRDPSWIGRGESTASQTAWALLALHAAGHGTGEPALRAVRWLVETQRPDG
GWDEPQYTGTGFPGDFYINYGLYRLVFPISALGRILDARHGALEATVTR
>A0A5J6VWT5|squalene-hopene cyclase|EC 5.4.99.17|Acidithiobacillus sp. 'AMD consortium'|TrEMBL
MNRMLQPVRSGAGIFRSSLDRVIAQARQALSGRQAEDGHWCFEFEADCTIPAEYILMQHY
MDERDEALQARIAVYLRGKQADHGGWPLYYGGHFDLSASVKVYYALKLAGDDPELPHMRR
AREAILAHGGAERSNVFTRITLALFAQVPWRAVPFIPVEIMLLPRWFPFHIYKVASWSRT
VMVPLFILCSLKARAKNPLQVHIRELFRRPPDQITDYFSHARQGIVAYFFLSLDRFWRLM
EGWIPHAIRRRALKKAEAWFTARINGEDGLNGIFPAMVNAHEALALLGYPPDHDYRRQTG
AALRKLVVERANDAYCQPCVSPVWDTCLALHALLEQDGEVSPAVQTGIRWLKDRQIGAEP
GDWRESRPHLAGGGWAFQYANPYYPDLDDTAAVGWALARAGRAEDRDSIEKAANWLAGMQ
SRNGGFGAYDVDNTHYYLNEIPFADHKALLDPPTADVTGRVVAFLAHLARPRDRDVLRRA
VAYLLREQESSGAWFGRWGTNYIYGTWSVLMALAELNDPSLKPTMERAAYWLRAVQQSDG
GWGESNDSYGDPGLAGVGQTSTAAQTAWACLGLMAAGDRDSVALHRGIAWLQAHQEGDGC
WQAPFFNAPGFPKVFYLIYHGYAFYFPLWALARYRNLGCMAHE
>A0A6G3QA64|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID12488|TrEMBL
MTATTDGSTGALPPRAASASESETETDINAPVAAGVQEAAERAMRRATDSLLARQDAQGW
WKGDLETNVTMDAEDLLLRQFLGIRDEQTTQAAALFIRGEQRDDGTWATFYGGPADLSAT
VEAYVALRMAGDAPEAPHMAKASAWIRDRGGMAAARVFTRIWLALFGWWKWDDLPELPPE
LIYFPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHIDPDLPNPGKSFAP
LASWDGAFQRLDRVLHGYRKVAVRRLRKAAMNAAARWIIERQENDGCWGGIQPPAVYSVI
ALHLLGYDLEHPVMRAGLESLDRFTVWREDGARMIEACQSPVWDTCLAVIALADAGLPAD
HPQLVKAADWMLGEQVVRPGDWSVRRPELPPGGWAFEFHNDNYPDIDDTAEVVLALRRVR
HHDPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSTLPNKLPFCDFGEVIDPPSADVT
AHVVEMLAVEGMSHDPRTRRGIEWLLAEQEPSGAWFGRWGVNYVYGTGSVVPALTAAGLT
AAHPAIRRAVGWLEKVQNDDGGWGEDLRSYDDSAGWSGRGASTASQTAWALLALLAAGEH
DSKAVERGVEWLAATQLPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEP
FAEAKGG
>A8LER3|squalene-hopene cyclase|EC 5.4.99.17|Frankia sp. (strain EAN1pec)|TrEMBL
MFQGSDRPPVTLVMNDMRGPDMNVSDTVSVTRESIPTQTSAGDATARDLTAAVGSELTRA
LRLATDHLLALQDGTGWWKFDLETNTSMDAEDLLLREYLGIRTTEVTAASARFIRSRQSD
DGSWPQYFGGPGELSTTVESYIALRLAGDDASAPHMLSAATWVRDHGGVPATRVFTRIWL
ALFGWWRWEDLPALPPEIMLLPRRAPLNIYSFGSWARQTLVSLTVVSALRPVRPAPFDLD
ELYPDGPASAWSGAGPSNVLERISTRFTAKEIFLGIDRLLHVYHRRPVRSMRNHALRAAE
RWIIARQEADGCFGGIQPPAVYSIIALRLLGYELDHPVLKAALRALDDYSVTLPDGSRMV
EASQSPVWDTALAVNALADAGATAAIAPDHPALVRAAGWLLGQEVRHRRGDWAVNHPDVP
ASGWAFEFENDTYPDTDDTAEVLLALRRVRHPARDELDAAERRAVAWLFGLQSSDGGWGA
YDADNTSTIPYQIPFADFGALTDPPSADVTAHVVELLAEAGLGGDDRTRRGVDWLLDHQE
ADGSWFGRWGVNYVYGTGSVMPALRAAGLEPSHPAMRAGADWLLTHQNADGGWGEDLRSY
TDPEWSGRGESTASQTAWAMLALLTVGDQPEVSGALARGARWLADHQRPDGSWDEDQFTG
TGFPGDFYINYHGYRLLWPIMALGRYLRG
>A0A6B2T9D7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID10116|TrEMBL
MTATTDGSTGAATPRAASASQSTETVLPIDTTAAGPREAAARAMRRSTDFLLARQDAEGW
WKGDLETNVTMDAEDLLLRQFLGIRDEDTTRAAALFIRGEQRDDGTWATFYGGPGELSTT
IEAYVALRLAGDRPDEPHMAKASAWIRDRGGIAEARVFTRIWLALFGWWKWDDLPELPPE
LIYFPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDARVPNPSKPLAC
VASWDGVFQRLDKALHVYHKVAPRPLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVI
ALHLLGYDLEHPVLKAGLASLDRFAVWREDGSRMIEACQSPVWDTCLATIALADAGVPAD
HPQLVKAADWMLGEQIVRPGDWSVRRPGLTPGGWAFEFHNDNYPDIDDTAEVALALRRVA
HPDKARLENAIDRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVT
GHVVEMLAVEGKSHDPRTRRGIEWLLAEQEENGAWFGRWGVNYIYGTGSVVPALITAGLP
ASHPAIRRAVRWVESVQNDDGGWGEDLRSYRDRGWVGHGTSSASQTAWALLALLSAGERE
AKSTERGIAWLVDAQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYINGEPF
AGGSDARTAKGS
>A0A8J6MXH9|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Desulfacyla euxinica|TrEMBL
MKQGIRTTFKVLTNQKRTISHSQQPDPIQKNVVKTPGPATSLFTVKRLNEAITKAKDRFL
AIQNAKGYWVFDLEADATISSEYIFLQRFLGREMPHDLKEGMGHYIRNRQIENGGWPLYH
AGEANISASVKAYFALKQLGDSPDAPHMVKAREFILNQGGAAKVNVFTRFTLALFGQIPW
RTTPAMPIEIMLLPKWFFFHLQKVSYWSRTVIVPLLILNAKQPVCHLRPEEGIAELFLES
PRKLRHLDHLIPRNLVKNLFILLDRVLKTVDSIIPRTTREKATRLAENWTVERMQGEGGI
GAIFPAMANAVMALRALGYPADHPDFTRGLKAIDDLLVTRGHEAFCQPCVSPIWDTCLSL
SALLESGLPPDHNAVKKATDWLFKELITRPGDWTHRAPDLEPAGWAFQFENSFYPDIDDT
PMVLMSLLRAGALDEEEYKQKIAKAVNWVIGMQSSDGGWGAFDIDNSYFYLNNIPFADHG
ALLDPSTSDLTGRCVEILSMLGYGHDFPPIAKALKFLRKEQEECGAWFGRWGVNYIYGTW
SVLKGLGALGENTSRPYIRRAVDWLKSCQNSDNGWGETSHSYSDPSIGGNGRSTPSQTGW
ALLGLMAVGEVKSSAVQRGIHYLLGNQNQQGVWDEEDFTGTGFPRVFYLRYHGYCQFFPL
WALSEYRRLRTEKMTRQNEVSLQRPTDLPLPVLKQRP
>A0A4Y9M6L3|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium niftali|TrEMBL
MDSVNATAREAQESKISESRILESKILESSIASATQGVLGLQQSDGHWVFELEADCTIPA
EYILLRHYLAEPVDTVLEAKIGNYLRRVQGAHGGWPLVHDGAFDMSASVKAYFALKMIGD
SIDAPHMVRAREAIHARGGAIHSNVFTRFMLAMFGVVTWRAVPVLPIEIVLLPFWSPFHI
NKISYWARTTMVPLMVIAALKPRARNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFLLF
RSLDAILRVIEPLFPKSLRKRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKD
ESYPPRAVTRRGIDKLLVIGDDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLD
WLIPKQELAVKGDWAVKRPDVRPGGWAFQYNNAYYPDLDDTAVVVMSMDRMRREHGVTGY
DAAIDRGREWIEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISML
AQLGETAKTSKHVADGVAYLRKTQHPEGSWYGRWGMNFVYGTWSVLCALNMAGVSHDDPM
IRKAAAWLASIQNKDGGWGEDAVSYRLDYKGWEPAPSTASQTAWALLALMAAGEVDHPAV
ARGVEYLIATQNEKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRV
VGVGM
>A0A522MSG6|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia sp|TrEMBL
MNDISAPSAVTAASSSSGAARSRAALETSIARATDAIVADQRPDGHWVYELEADATIPAE
YILLVHYLGEAPNVELERKIVRYLRRIQLADGGWPLFTDGAMDVSASVKAYFALKMAGER
EDAEHMRRARAAILGAGGAEAVNVFTRILLALFAIVPWSAVPMMPVEITLLRQWFPFHLS
KVSYWARTVIVPLLVLNARRPVAKNPLGVRIDELFLGDPSATGLLPRAGHQSRGWFAFFR
VVDSILRGVDGWFPRRTRERAVQKAVAFVDERLNGEDGLGAIFPAMANAVMMYDALGYGP
DYPNRAIARASLDKLLVIGDEEAYCQPCLSPVWDTSLVAHALLEVETPPAQDAALRGLQW
LRPLQVLDVRGDWISRRPDIRPGGWAFQYANPHYPDVDDTAVVAMAMHRAAALTRSNVDR
EAIARAREWIVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLA
QLGELPGNSDPARRAYDYLLAEQEDDGSWYGRWGMNYVYGTWTALCALNAAGIAHDDARI
KRAAQWLIAIQNEDGGWGEGGESYKLDYRGYEPAPSTASQTAWALLGLMAAGVIDHPAVT
RGIDYLVRTQCEHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLTRDGRARV
AVGM
>A0A375J7R8|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus taiwanensis|TrEMBL
MSMNETAFANAAPQLDSAPRQPAGPQQAPATRLPAPALDHGIERALDTLLRQQRPDGHWV
YELEADATIPAEYVLMVHYLGEAPDLELEARMARYLRRIQNPDGGWPLFHQGRSDVSASV
KAYFALKMAGDDPQSAPMQRARQAIHAMGGAEASNVFTRTLLALYGVLPWKAVPMMPVEI
MLLPRWFPFHLSKVSYWARTVIVPLLVLNSLRPQARNPRGVGINELFVGNCHTVGLPPRA
PHQHAGWYTVFRGLDALLRVAEPLFPRTLRRRAIATARRFVRERLNGEDGLGAIFPAMAN
SVMMFDVLGVPPDDPARAVARRSLERLLVEHGDEAYCQPCLSPVWDTALATHALLETGDA
RAAQAAGRALDWLRPLQVLDLRGDWAVRRPLVRPGGWAFQYANAYYPDVDDTAVVAAAMD
RFMRAHHAPGRYGEAVARATEWIVGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDPP
TADVSARCLSMLCQTGAPPGKSEPAARALRYLLAEQMPDGSWFGRWGTNYIYGTWSALCA
LNAAGLPPAAPELQRAVAWLARIQNADGGWGEDGSSYRLDYRGYEPAPSAASQTAWALLA
LMAAGAAQHPAVARGIDYLLRTQQPGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWALA
RYRNLQRGQMGQSGQVSWGL
>A0A3G3LBP9|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia gladioli|TrEMBL
MNDLTDSTTSDGATPNAAPSPAAGAANLPATSAVTAAQDATPIVADHAPAAPAAPAAPAA
PAATAATAATAATAATAATAATAATAAAAEATTQAAAATPVAPVAAKLPSPAELDIAVTR
ATDALLAAQQADGHWVYELEADATIPAEYVLLVHYLGETPNAELERRIGRYLRRIQLPGG
GWPLFTDGAPDVSASVKAYFALKMIGDDVEAEHMVRARQAIHAMGGAEMSNVFTRIQLAL
FGVVPWFAVPMMPVEIMLLPQWFPFHLSKVSYWARTVIVPLLVLNAKRPLAKNPLGVRVD
ELFVNPPVNTGLLPKQGHQSTGWFLLFRGVDGLLRLTDGLFPRYSRERAIRQAVQFVDER
LNGEDGLGAIYPAMANSVMMYAALGYPEDHPNRAIARRSLDKLLVIKDDESDEAYCQPCL
SPVWDTTLAAHALLETGEPRAEAAALRGLEWLRPLQILDVRGDWVSRRPHVRPGGWAFQY
ANPHYPDVDDTAVVVLAMDRAARLTQSDVDRDAIARAREWVVGMQSSDGGWGAFEPENTH
HYLNNIPFSDHGALLDPPTADVSGRCLSMLAQLGETNVNSQPAQRALDYLLAEQEADGSW
YGRWGMNYIYGTWSALGALNAAGLGHDDPRVKRAAQWLLSIQNPDGGWGEDGTSYKLDYR
GYEPATSTASQTAWALLGLMAAGEVDHAAVARGIDWLIAEQKTHGLWDETRFTATGFPRV
FYLRYHGYRKFFPLWALARYRGLKRAGTTRVTVGM
>A0A7Y5JGI2|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetaceae bacterium|TrEMBL
MSKAHQTLHRELTRKKGGSHRKIRNILHELEGLESLLEKFSAQPRRADRSNDPALDVAIA
RQQSRMLAIRDKGEVYWNAELDSNAGLGAEYIMMLHFLGIAGQPEWAERQRKVANYTRQW
QNKDGSWSIYARGPGHLSYSVTCYFGLKLAGDSSDAPHMVKARDWIRAHGGAMLIGVEQR
FLLALFGQYDWAGVPPIPSWMVLLPHLPMLPRALENKLLNIYDLSYWCRISLVPMSVLYQ
LKPLVRIDERLGVEELFLEPKGERRWSFAPVSEPGLMSWGGLFSVGAKAVKALEFATNGV
VAKVALNKAQKWILDHQDDSGDWGGIYPPIMYNIMALSRLGMPLSDARILKAFKALDRFM
IYHAHCDGLHVQACVSPVWDTAWALYALGESGFDTRDTEFQRGIDWLYSRQILRDGDWAV
KNPDAIPGGWCFQFYNDFYPDLDDTAVVLQALLFGGYPKGLGGRVEQTRIGLEWVLSMQN
QDGGWSAFECGVDKALVNHIPFNDLNNMLDPSTADVTGHVLEMLGHFGFDLSFAPCRRAA
EYLRKNQDREGARAGSWWGRWGVNYVYGTWSALAGLAQVGEDMSKPYVRKAVAWLYGVQN
EDGGWGEGCETYKEPERAGREISGQSTPSQTAWALLGLLAAGEVDDSRLRRGVAWLLNRQ
LPQGGWEEELYTGTGFPNAFYLNYHFYREYFPLLALGRYRNAKCGLKPI
>A0A7Y6SGD3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. CAI-17|TrEMBL
MTATTNGPAGAAPSRPAPARTTAATTDTAALDGAAVEAAAERARARAADHLLGLQSPEGW
WKGDLDTNVTMDAEDLLLRQFLGIRDEATTRSAALFIRGEQREDGTWATFHGGPPDLSTT
VEAYVALRLAGDSPDAPHMTRAAHWVRSQGGIAEARVFTRIWLALFGWWPWDRLPELPPE
LIFLPPWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPADPAPRARFAP
LASWNGAFQRLDRALHAYRKVAPRALRRAAMATAGRWIVERQENDGCWGGIQPPAVYSMI
ALHLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALADAGVPAD
HPQLVRAADWMLDEQIERPGDWSVRRPHLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVR
HPDTARMERAISLGVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDPPSADVT
AHVVEMLAAEGLAADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALVDAGLP
TTHPAIRRAVAWLESVQNDDGGWGEDLRSYREQGRMARGASTASQTGWALMALLAAGERE
SRAARRGVTFLAETQHEDGSWEEPYYTGTGFPWDFSINYHLYRQVFPLTALGRYTRGAAP
EGA
>A0A4Q2A8F3|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia stabilis|TrEMBL
MIRRMNKPPPSSWSALDTAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDVRQEQMARYLRANQRLDTHGGWALYVDGAPDVSCSVKAYFALKAAGDSEHAPHMVRA
RDAILKLGGAARSNVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNISIGELFVTPPDAERHYFPPARGMRKLFLALDRTVRHIEPL
MPKRLRAHAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMDVLGYPDDHPLRRDCENAL
EKLLVTRPDGSVYCQPCLSPVWDTAWSTMALEQARGVAAPEAGETAGALRELDARIARAY
DWMAERQVNDLRGDWIENAPADTEPGGWAFQYANPYYPDIDDSALVTAMLDRRGRTHRNA
DGTNPYAPRVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRADDRASLARCIDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALAGED
KSQPYIARALDWLRARQHADGGWGETNDSYIDPKLAGTNAGESTSNCTAWALLAQMAFGD
CESDSVKRGIAYLQSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GMTLASDHDAATTERRVSETA
>A0A5P3VD33|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus oxalaticus|TrEMBL
MSMNETAFATTAPPIRIAADPAFAPAFGQQSAAQELDHGIGVAVDALLHQQRPDGHWVYE
LEADATIPAEYVLMVHYLGEAPDLALEARIARYLRRIQNADGGWPLFHDGRADVSASVKA
YFALKMAGDDPQAPHMARARQAIHAMGGAEATNVFTRTLLALYGVMPWTAVPMMPVEIML
LPRWFPFHLSKVSYWARTVIVPLLVLNSLRPRARNPRGVGIGELFSNPRRSVGLAPRAPH
QHAGWYNLFRGLDALLRVAEPAFPGLLRRRAIAAAQRFVRERLNGEDGLGAIFPAMANSV
MMFDVLGVPADDPARAVARRSVERLLVEHGDEAYCQPCLSPVWDTALAAHALLETGEARA
AAAVGRALDWLKPLQVLDVRGDWSVRRPRVRPGGWAFQYANAHYPDVDDTAVVAAAMDRY
MREHAAPGRYDEAAARAAEWIVGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDPPTA
DVSARCLSMLCQTGATPASSEPAARALRYLLAEQMPDGSWFGRWGTNYIYGTWSALCALN
AAGLGPDAPAVRRAADWLAGIQNEDGGWGEDGGSYRLDYRGHEPAPSVASQTAWALLALM
AAGAVQHSAVARGIGYLLRTQRPPQEGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWAL
ARYRNLQRGGDDGGGGEGRVTWGL
>A0A2L2XX61|squalene-hopene cyclase|EC 5.4.99.17|Microcystis sp. 0824|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYPDGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPANDPTLEKAREFI
LAQGGISKTRIFTKMHLALIGCYDWLGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKSNNWSDVFLWLDGLFKWTEKTNLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVDDPIVARGLKAVDNFAIE
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKAVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A5J6IF23|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces coeruleorubidus|TrEMBL
MTATTDGSTGALPPRAAAASETDTDTPVAAGVQEAAARAAQRATDFLLSRQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDEKTTRAAALFIRGEQREDGTWATFYGGPGELSATIEAY
VALRLAGDEPGAPHMAKASAWIREQGGIAAARVFTRIWLALFGWWKWEDLPELPPELIYF
PKWVPLNIYDFGCWARQTVVPLTIVSAKRPVRPAPFPLDELHTDPAHPNPAKPLAPVFSW
DGAFQRMDKGLHALRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLQHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLAAIALVDAGLPADHPQL
VKAADWMLGEEIVRPGDWSVQRPGLPPGGWAFEFHNDNYPDIDDTAEVILALRRITHHDP
VRVAKAVGRGVRWTLGMQSKNGAWAAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIEWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALVAAGIPAAHP
AIRRAVTWLEAVQNDDGGWGEDLRSYKYVREWSGRGASTASQTAWALMALLAAGERDSKA
VERGIEWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGEPFADR
HQGGGAAGKPLADAKGS
>A0A6H1NGF3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. S1D4-11|TrEMBL
MTATTDGSTGALPPRAAAASEIHPETTPVAAGTVETRDVATHAIQRATDFLLSRQDAEGW
WKGDLETNVTMDAEDLLLRQFLGIRDETTTRAAGLFIRGEQREDGTWATFYGGPGELSAT
IEAYVALRLAGDGPDEPHMARAAAWVRERGGIASARVFTRIWLALFGWWKWDDLPELPPE
LIYFPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDARDPNPVKPLAP
VASWDGVFQRLDKALHQYRKVVPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVI
ALHLLGYDLQHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPAD
HPQLVKAADWMLGEEIVRPGDWAVKRPHLPPGGWAFEFHNDNYPDIDDTAEVALALRRVR
HHDPERVEHAIGRGVRWNLGMQSKDGGWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVT
AHVVEMLAVEGLSHDPRTRRGIEWLLAHQEPDGSWFGRWGVNYVYGTGSVLPALVAAGLP
ASHPAIRRAVAWLETVQNDDGGWGEDLRSYHEVAEWSGRGASTASQTGWALLALLAAGER
GAKAVERGIAWLAETQLADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEP
SFVHGESFAEVKGG
>A0A2I2KL80|squalene-hopene cyclase|EC 5.4.99.17|Frankia canadensis|TrEMBL
MSLTSDPSPAAPAAEQSVKRPTIPVPATADAYGISRSSPPLPTASAPRESTATDGAAPAP
AAGSGPISADTAAARARDHLLALQDDEGWWKGDLETNVTMDAEDLFMKQFLGIREAEETE
QTARWVRSQQLDDGGWATFYGGPADLSTTIEAYIALRLAGDAVDAPHMARAAELVRAKGG
VAASRVFTRIWLAALGQWSWDDVPVIPPELIFLPSWVPLNVYDFACWARQTVVALTIVGS
LRPSHDLGFDIDELKVAAPARKLAPLRSWEGVFQRLDRALHRYERRPIGLLRTLALRRAT
EWVVARQEADGCWGGIQPPWVYSVMALHLMGYPLNHPVIATAFRGMERFVIRRDTPEGPI
RQIEACQSPVWDTALAVVALADAGVPADHPAMVKAGRWLVDEEVRVAGDWAVRRPELAPG
GWAFEFDNDFYPDVDDTAEVVLALRRLLGAEHVVPPALRGAYEHAAAGRPTVEDADPALA
AAMRAAAARGVDWSVGMRSSNGAWGAFDADNVRMLATKIPFCDFGEVVDPPSADVTAHLV
EMLADLGRSDHPITQRAVQWLLDNQEPGGSWFGRWGVNHVYGTGAVVPALIAAGVPTDHP
AITAAVRWLVEHQAPEGGWGEDLRSYTDPAWIGRGALTASQTAWALLALLAVDPNSLAVR
RGVRWLCETQRPDGTWDEPYFTGTGFPWDFSLNYNLYRLVFPLTALGRYVSLTGVSTS
>B8IKA1|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060)|TrEMBL
MGKVETLHRMSTQDITLDDVERRVSLASKALMRLAGPDGHWCFELEADATIPSEYILYHH
FRGSIPSAELEGKIANYLRRTQSAQHDGWSLVHDGPFDMSATVKAYFALKMIGDSIEAPH
MRRAREAILRRGGAAHANVFTRTLLALYGEVPWSAVPVMPVEVMLLPRWFPFHLDKVSYW
ARTVMVPLFVLQAKKPRARNPRGIGIQELFVEPPERVKRWPAGPQESSPWRPVFAAIDKV
LQKVEGSFPAGSRARAIDKAVAFVSERLNGEDGLGAIFPAMVNAVLMYEALGYPEDHPLV
ATARSSVEKLVTVKEHEAYVQPCLSPVWDTALSAHALMEAGGVEAERHAKRALDWLKPLQ
VLDIKGDWAASKPNVRPGGWAFQYANPHYPDLDDTAVVVMAMDRAQVRRSPGPDAADYGQ
SIARAREWVEGLQSRDGGWAAFDADNTYHYLNYIPFSDHGALLDPPTADVTARCVSMLAQ
LGETRESCPPLDRGVAYLLADQEADGSWYGRWGMNYIYGTWSVLCALNAAGVDPASEPVR
RAVNWLTTIQNPDGGWGEDAASYKLEYRGYERAPSTASQTAWALLGLMAAGEADSPAVAR
GINYLTRSQGADGLWTEDRYTATGFPRVFYLRYHGYAKFFPLWALARYRNLQQSNSRRVA
VGM
>A0A7W7YM09|squalene-hopene cyclase|EC 5.4.99.17|Prosthecobacter dejongeii|TrEMBL
MLNSVHLALTQTEAHLLALRQPTGHWEGQLSSSALSTATAVVALRGVDAVAHADLIAAGV
QWLITHQNADGGWGDTTVSKSNLSTTLLCYSALHAAAASGTAAQAALAQAAAWITTQVGS
LKPEAIAQAVIRRYGKDKTFSVPILMLCTIGGTLGDKAWRRVLPLPFELAALPRSWFGAV
GLPVVSYALPALIAIGHARFKNAPPAWWNPLRWLRAALWPRIRPMLQTLQPSSGGYLEAT
PLTSFVTMALAAAGEKDHPCIPGAIAFLKRSMRADGSWPIDTNLATWGTTLASKALGHTD
ERVRHWLQGQQYQTMHPFTNAAPGGWAWTDLPGGVPDADDTAGALIAMKLTPGEGTGGPA
QAGITWLLDLQNRDGGMPTFCRGWGTLPFDRSTPELTAHALLAWWLWEKDLPPAQRQRVA
HATRQALKYLRRTQRADGSWIPLWFGNEHTPDEENPVYGTAQVVAYLSSTEALAAQASDL
IESGRRYLLTRQKTDGSWGGDLHAPSSIEETSVALHALLLQPGPQPQDYATRATLWLVAT
TQHGTHFPTAPIGLYFARLWYHEQLYPIIWTLQALRRVKAVLPTVSEPGTTTPT
>A0A846N0V4|squalene-hopene cyclase|EC 5.4.99.17|Rhizomicrobium palustre|TrEMBL
MNMNVKMNAPAETVPVDALIKAATDAILREQRPDGHWVYELEADATIPAEYVLLTHFLGE
EPNLELEKKIGVYLRRIQGEHGGWPLYHKGALDISATVKAYFALKMIGDDPEAPHMKRAR
EEILKRGGAGKANVFTRIQLALYGDVPWSIIPTIPPELILLPRWFPIHLSKMSYWARTVI
VPLLVLAAKQPIARNPRGVHVKELFLPGKVASKRAAHQKWIWSAFFGALDWVLKRVEPFW
PQKLRAHAIKTCMEWTTERLNGEDGLGAIYPAMANSVMMYDTLGVGPEDPRRAIARVSVE
KLLVIKEDEAYCQPCVSPVWDTGLVCHALMETRDPKVHEAVTKGLEWLKPLQVLDVKGDW
AEEKPGVRPGGWAFQYRNDYYPDLDDTAVVVMALDRAKEIEGQKSDYSEAISRGREWVEG
LQSKNGGWGAFDADNSYYYLNNIPFADHGALLDPPTEDVSGRCIGMLAQLGEANDTPRMK
AAIEYLEKVQMPDGSWFGRWGVNYIYGTWSALAGLNAAGIDHSHPMIRKAVDWLVTIQNE
DGGWGEDCDSYKLEYKGYEKAPSIASQTAWALLGLMAAGEVDHPAVARGVRWLEANQGAD
GLWPQEYYTGGGFPRVFYLRYHGYPKFFPLWALARYRNLKTGNSRKVGHGL
>F0SKM5|squalene-hopene cyclase|EC 5.4.99.17|Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / IAM 15109 / NBRC 103401 / IFAM 1448)|TrEMBL
MASGLETQPMNLDDAYIRCSGLLLDHRTHDGHWEGELSTSALSTATAVMAMHQVVSRNAS
VAKKYDLQPLIEQGLAWLTEHRNDDAGWGDTVKSISNISTTMLVRAVFAATAGKYATPAE
VDNRYLKEVDDHIARVGGIAAVKARYGKDRTFSVPILMQCALGGLADWSQVEQLPFELAC
LPADWYKTAQLPVVSYALPALITIGLARHRKKPTRFLHWRWLRNAAAPSALNVLQRIQPT
TGGFLEATPLTSFVTMSLVAADEQEHPVVHEAIRFLVDSVRDDGSWPIDTNLATWVTTLS
LNALGPDVPDEQVDPALDWILAQQYRTKHPYTNADPGGWAWTDLPGGVPDADDTPGAILA
ILELRSRTDAMRAERINGAAHDAVGWLLSLQNRDGGWPTFCRGWGKLPFDRSSPDISAHC
LRAIVRFLREACNDAALAARCQKAIERGYRFLIGRQRNDGAWLPLWFGNQFANDDENPTY
GTARVLLAFDPDAESDRNSSGPLQRGLEFLQSIQNADGGWGGAMGTPSSVEETSLALEAL
VHARGSREAVERGAHWLMKKLAAGEIDETTPIGFYFAKLWYFEQLYPLIFATAALRHARE
YLAR
>A0A7W9WEV6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces paradoxus|TrEMBL
MTATTDGSTGALPPRAAAASDTDTHTPGTAGVPEAAARAARRATDFLLSRQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDEKTTQAAALFIRGEQGEDGTWATFYGGPGELSATIEAY
VALRLAGDAPDAPHMAKASAWIRAQGGIAAARVFTRIWLALFGWWKWEDLPELPPEFVFL
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPDRPNPPKPLASPFSW
DGAFQRMDKGLHALRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLEHPVMREGLASLDRFAVWREDGSRMIEACQSPVWDTCLAVIALVDAGLPPDHPQL
VKAADWMLGEEIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVILALRRIAHHDP
ERLDRAIVRGMRWTLGMQSKNGAWAAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAIEGLAHDPRTRRGIEWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALTAAGLPAAHP
AIRRAVAWLESVQNDDGGWGEDLRSYRDVRRWSGRGASTASQTAWALMALLAAGERDSKA
VERGVEWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFADR
LKGS
>A0A3E0KZ10|squalene-hopene cyclase|EC 5.4.99.17|Microcystis flos-aquae TF09|TrEMBL
MQIQEKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
KRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKGREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNNWSDVFLWLDGLFKWTEKTDLVPFR
QESLQAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVDDPIIARGLKALDNFAIQ
RDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKSVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYSDLKAMIDPNTADVTARVLEMLGTCDVKMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYQALI
>A0A7W7LEL9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces netropsis|TrEMBL
MTATTDGGTGAGSPPAAAANESTTVLPPAARAGQAEPHAAAERATARAVEHLLARQDTAG
WWKGDLETNVTMDAEDLMLRQFLGIQDERTTRAAALFIRTEQRPDGTWSTFHGGPAELSA
TIEAYVALRLAGDAPEAPHMAAAALWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPP
EIMYLPKWFPLNIYDFGCWARQTIVPLTVVSAERPVRPAPFPLDELHTDPRRPNPPRPAA
PAASWDGLFQRLDKALHVYRRFALAPLRRTALRAAERWIIERQENDGCWGGIQPPAVYSV
IALHLLGYDLRHPVLRAGLESLDRFAVWREDGARMIEACQSPVWDTCLAVIALADAGVAA
DHPALVKAADWMLDEQITRPGDWTVRRPDLPPGGWAFEFHNDNYPDIDDTAEVVLALERV
RHPDPGRVETAVRRATRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADV
TAHVVEMLAVLGRQHDPRTRRGIDWLLAEQEPSGAWFGRWGTNYVYGTGSVLPALVAAGL
PVSHPAVRRAVAWLESVQNADGGWGEDQRSYRDPEWIGRGATTPSQTAWALMALLAAGER
ESKAVERGVAWLVENQRPDGSWDEPHFTGTGFPWDFSINYHLYRQVFPVTALGRYLHGEP
FTPDRREG
>A0A7K2ZUF5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8379|TrEMBL
MTATTDGSTGAAAPDATSATTARTTDTTPEAAGTHSAATRAIQRATDFLLARQDAQGWWK
GDLDTNVTMDAEDLLLRQFLGIRDQATTDASALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDAPDAPHMATASAWIRERGGIAASRVFTRIWLALFGWWKWDDLPELPPELI
YFPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDARNPNPPKPLAPVA
SWDGAFQRLDKIMHGYQKVALKRLRKAAINSAGRWIIERQENDGCWGGIQPPAVYSVIAL
HLLGYDLQHPVLKAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPGDHP
ALVKAADWMIDEQIDRPGDWSVRKPQLEPGGWAFEFHNDNYPDIDDTAEVVLALRRVDHP
DKVRLEKAIERGVRWNLGMQSKNGAWGAFDVDNSSPFPNLLPFCDFGEVIDPPSADVTGH
VVEMLAVEGRSRDPRTRRGIEWLLAEQEDNGAWFGRWGVNYVYGTGSVLPALVAAGMPAA
HPAIRRAVDWLESVQNEDGGWGEDLRSYRYEDWKGHGVSTASQTAWALMALLSAGERDSK
AVERGITFLADTQTADGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFGD
RDS
>A0A3D8K6Z6|squalene-hopene cyclase|EC 5.4.99.17|Trinickia dinghuensis|TrEMBL
MNDISAPAAVMAASSPADAAQTGVALDAAITRATDAILADQRPDGHWVYELEADATIPAE
YILLVHYLGETPNLELERKIVRYLRRIQLTDGGWPLFTDGAIDVSASVKAYFALKMAGER
EDAEHMQRARAAILGAGGGEAVNVFTRILLALFGVVPWSAVPMMPVEITLLPQWFPFHLS
KVSYWARTVIVPLLVLNARRPVARNPRGVRIDELFLGAPSEAGLLPRAGHQSRGWFAFFR
VVDTVLRGVDGLFPKKTRERAIRAAVAFVDERLNGEDGLGAIFPAMANAVMMYDTLGYGP
DYPNRATARASIEKLLAVADDEAYCQPCLSPVWDTSLVAHALLETEAPKAQEAALRGLQW
LRPLQVLDVRGDWISRRPDIRPGGWAFQYANPHYPDVDDTAVVAMAMDRAAALTRSNVDR
EAIARAREWIVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLA
QFGELPGNSEPARRAYDYLLDEQEDDGSWYGRWGMNYVYGTWTALCALNAAGIAHDDARI
KRAAQWLISIQNEDGGWGEDGTSYKLDYRGYEKASSTASQTAWALMGLMAAGVVDHPAVA
RGVAYLVDEQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNRVRV
AVGM
>A0A6I4NIH9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. BA2|TrEMBL
MTATTDGSTGAVTPRATSASQPLVQTVATAAGPRDAAARAIQRSTDFLLAQQDAQGWWKG
DLETNVTMDAEDLLLRQFLGIRDEKTTRAAALFIRGEQRDDGTWATFFGGPGELSTTVEA
YVALRLAGDAPDDPHMAKASAWIRDQGGIAASRVFTRIWLALFGWWKWEDLPELPPELIY
FPKWLPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHSDARVPNPGKPLAPMGS
WDGVFQRLDKALHLYHKVAPRKVRKAAMNSAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVLKAGLASLDRFAVWREDGSRMIEACQSPVWDTCLATIALADAGVPADHPQ
LVKAADWMLAEEIARPGDWSVRRPQLAPGGWAFEFHNDNYPDIDDTAEVILALRRVEHPD
RPRLENAIERGMRWTLGMQSRGGAWAAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHV
VEMLAVEGKAHHPRTRRGIEWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALTAAGLPGSH
PALRRAVGWLESVQNDDGGWGEDLRSYRYEEWRGHGASTASQTAWALLALLAAGERESKA
VERGVAWLAETQRDDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPFAGL
STKGG
>A0A5Q4SLE7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. wa22|TrEMBL
MTATTDGSTGAANLRAAPASDPTESTSAAHDMMAVARHAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETVKAAARFIRGEQLGDGTWNTFYEGPPDLSATVEAY
VALRLAGDRPDDPHMIRAAGWVREQGGIAESRVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPSCPNPPKPTAPAASW
DGVFQRLDKALHLYHKVAPRRLRRIAMNEAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVGPDHPAL
VRAADWMLGEEIVRPGDWAVRKPELAPGGWAFEFHNVNYPDIDDTAEVALALRRVRHPDP
ARVDAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGRSHDPRTRRGVEWLLAEQEASGAWFGRWGVNYIYGTGSVVPALIAAGLPAPHP
AVRRAVDWLKSVQNDDGGWGEDLRSYREEKWIGHGSSTPSQTGWALLALLAAGERETRSV
ERGVAWLAATQQADGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFATAS
AIGAGTGKGA
>A0A7C5EPU3|squalene-hopene cyclase|EC 5.4.99.17|Desulfobacca acetoxidans|TrEMBL
MPVVSAGGSRSKVPPRSLVDRVRKARDRAASALLALQKPEGYWWAELEANVTITAEYLLL
QRFLGLPRKDFPRLAREILSQQLPNGGWSIWYGDEGDLSTTVEAYLALKVAGLDQDFGPL
QKARQFIRERGGVLKSRVFTRIFLALFGQVSWDGIPLMPVEFILLPPWTGLSIYELSSWS
RATVVPLSVVMARRPVCPLSSQEGVRELFGDPDEPFLRHRVRWKKGGSFLENFFIVVDQV
LKLYDRHPLPLVRRLALNRAEQWILAHQEETGDWGGIQPAMLNSLLALACLGYRLDHPVM
QRGLAALRFFTLDFGDRLRLQSCISPVWDTALALRALAAAGLPLGHPALVRGATWLLGKQ
ILKPGDWSIKRPKLAPGGWAFEFVNHWYPDIDDSAMVLMALKETLADLSSHQEAVNRGIA
WCLGMQSRNGGFAAFDVDNTKEWLNAIPFADLKALIDPPTEDVTGRVLEMMGTYGYSLRH
PAAQRALNFLKKRQHPAGPWWGRWGVNYIYGTWSVLLGLRAIGENMQAPYVRRAVSWLKE
HQLPNGGWGECCESYPNPELMGQGVPSASQTAWALMALMAAGETASPEVQKGIRYLLETQ
KKDGRWEEEHFTGTGFPGHFMIRYHLYRDCFPLMALGLYIREMEGQ
>A0A7V4G7Z6|squalene-hopene cyclase|EC 5.4.99.17|Desulfobacca acetoxidans|TrEMBL
WGGIQPAMLNSMLALFCRGYQPDHPVMRRGLKALEFFTLRFGNRLRLQSCISPVWDTALA
LRALAAAGVAGSEPALQKAAHWLLAMQIFRPGDWCIKRPKLAPGGWAFEFVNNWYPDIDD
SAMVLMALKETLGDMSPHQRAVDAGIGWCLGMQSKNGGFAAFDVDNTKEWLNSIPFADLK
ALIDPPTEDVTGRALEMLGLFGHDLSHAAARRALAFLKARQHPDGPWWGRWGVNFIYGTW
SVLMGLAAIGEDMKAPYVRRAVAWLKAHQNPDGGWGETCASYRHPELRGQGESTASQTAW
ALMGLMSAGEAGSPEVRLGIEYLMKTQHKDGRWREPQFTGTGFPIHFMIRYHLYRHYFPL
WALGKLARIGLAPPTSGVA
>A0A419I5M9|squalene-hopene cyclase|EC 5.4.99.17|Amycolatopsis panacis|TrEMBL
MTQTVPEPAVVAQPAPESALTAAIGFLRREQHPAGWWKGELATNVTMDAEDLLLRQFLGI
LTPRVAQESARWIRSQQRADGTWANFPGGPADLSTTVEAWVALRLAGDPADAPWLATAAE
YIRGHGGLEGTRVFTRIWLALFGQWSWDELPNMPPELIFLPSWFPLNVYDFACWARQTIV
PLTVVGTLRPVRDLPFDVAELRIGEHPAKTRTPWTWDGLFQNLDTALHVYAKLPVNPVRK
VALKQAAEWILARQEADGSWGGIQPPWVYSILALHLLGYPLDHPVLKAGIEGLDGFTIRE
ETEQGWVRRLEACQSPVWDTALAMTALLDAGVSPGDEMLVRATDWVLGEEIRVTGDWSVR
RPRLAPGGFAFEFANDGYPDTDDTAEVVLALRRMGKPDHLRIRAAVDRSVRWLEGMQSRD
GGWGAFDVDNTQVLATKLPFCDFGAVIDPPSADVTAHVVEMLAAEGKADTPECRRGVQWM
LDHQEPDGSWFGRWGTNYVYGTGAVVPALVDAGIPAGDPRIRRAVRWLSEHQNADGGWGE
DLRSYRDPAWAGRGDSTPSQTAWALLALLAAGERESEAVTRGVAWLCERQRPDGGWDEDK
HTGTGFPGDFYLSYHLYRVVFPLSALGRYVRGGS
>A0A372GBQ3|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. LHW52907|TrEMBL
MTAVEEPTTGREDVRRTAADALEAARDHLLLLQSPEGWWKGELQTNVTMDAEDLLLREFL
GVRTDDDTREAARWIRSQQAPDGTWANFHDGPPELSTTVEAYVALRLAGDPPDTPHMARA
AAYVRGEGGVPATRVFTRFWLAMFGRWSWDDLPIVPPEMIFLPRWFPLNVYDFACWARQT
IVPLSVVGALRPVRPLPFELGELYPGYDVPLPEKRAPSGWDLVFGTLDKALHVYERRPVK
TVRRAALRRAADWIVARQERDGCWGGIQPPWVYSVLALHLLGYGVDHPILQRALDGLERF
TIRDERGRRVEACQSPVWDTALAMNALTDAGLPAGHPAVERAADWLIREEVKGPGDWSVR
RPDLPPGGWAFEFDNDCYPDVDDTAEVVLALNRVRHPAAEPAIERGVRWMAGMVSRDGGF
GAFDADNTRALCRRLPFCDFGEVIDPPSADVTAHVVEAMAHRGMADSRLVKRAVVWLLKA
QEPDGSWFGRWGANHVYGTGGVVPALIAAGVRPDRPVIRNAVGWLERHQRDDGGWGEDLR
SYRDRCWVGHGASTASQTAWALLALLAAGERGASVERGVRWLVERQREDGTWDEDHFTGT
GFPGDFYINYHLYRLVFPLSALGRYLKGS
>A0A3S0TAJ5|squalene-hopene cyclase|EC 5.4.99.17|Hyphomicrobium sp|TrEMBL
MNYESASQSARLASEAVTRDISLAEVERAIGSAKDALLAIQRDDGHFVFELEADATIPAE
YILMRHYLAEPVDQVLEGKIANYLRRIQSDDGGWPLFHDGASNISASVKAYFALKMTGVG
VDEPYMKKARGWILSQGGASHSNVFTRNLLALFGAIPWRGVPVMPVEIMVLPRWFPFHLD
KISYWARTVVVPLTVLNALKPLARNPKGVGIPELFTIPPDQVKVWPKGPHQKSPWAEIFG
IIDRVLQTTQPYFPKSLRKKSIDKAVAFVDERLNGEDGLGAIFPAMVNALLVYDALGYPT
DHPNYKTARGSIEKLVTIKEDEAYCQPCLSPVWDTALTAHALMEVGGEQAERSSDRALEW
LKPLQVLDTIGDWAATRPNVRPGGWAFQYANPHYPDTDDTAVVVMAMDRALGRNAQHDTT
TREAIARGREWVVGMQSKNGGWGAFDADNTYEYLNQIPFSDHGALLDPPTADVSARCVSM
LAQLGERRGQCFELDKAIDYLERTQEKDGSWYGRWGMNYIYGTWSVLCALNAAGVDPSSS
VVRKAVKWLLSIQNSDGGWGEDGESYKLDYKGYEPAPSTASQTAWALMGLMAAGEIDNPA
VKKGVSYLAATQAGDGFWNEKRFTATGFPRVFYLRYHGYSKFFPMWALARYRNLKVSNTK
AVLVGM
>A0A1G5SCD1|squalene-hopene cyclase|EC 5.4.99.17|Nitrosomonas mobilis|TrEMBL
MKKFPAFLSGLSQQNIFKKAITGIHKISFPSQWMAAAGQIKAQRKINRGALTNTITEARA
ALLGLQQEDGHWCWPLEADCTIPAEYILMMHFMDEIDLTLEAKLANFIRVKQVQEHGGWS
LYYAGDFDMSCSVKSYYALKLAGDSAEAAHMLRARETILAHEGAARANVFTRLMLAMFQQ
IPWRGVPFVPVEIMLLPRWFPFHLSKIAYWSRTVSVPLSILCSLKAKAANPRKINIQELF
TVPPEEEKNYFPIRTRLNRVLLYVERLGSMLEPLIPSFIRRKALRLAEQWIMERLNGKDG
LGAIFPAMINAYEALALLDYEYAHPSRQICRKALRNLVVEEDEQAWCQPCVSPVWDTVLT
CLALQEGHQHIDSEPVQRALDWLVPLQILDEPGDWRDQHPDLLGGGWAFQYANPHYPDLD
DTAAAAWAMQQADADRYQESLKRAADWLAGMQSSNGGFAAFDSDNTHYYLNEIPFADHGA
LLDPPSSDVTARCVGFLALYGEARHQPAIARGLAYLLAEQEASGAWFGRWGSNYIYGTWS
VLEALRLAKVDLDHVAVRRAVQWLKSVQRSDGGWGESNDSYLDPGLAGQMQESTSFQTAW
ALLGLMAAGETDSQAVRDGINHLIAMQQVDGLWHEPWFTAPGFPRVFYLKYHGYSKYFPL
WALNRYRTFTS
>A0A8B5Y1F7|squalene-hopene cyclase|EC 5.4.99.17|Peribacillus simplex|TrEMBL
MQRQVLNIHINGKCVFRGGKSLNQHVQLEINRLVHRLKQDQSADGSWNYPFDTGITADAY
MIILLKILDMEDAPLIEALVKRIESKQTENGSWKLFQDEKDGNVTVTIEAYYGLLFSGLR
NKHDPHMKKAKQFILSKGGIKQAKMLTKMMLTVTGQYQWPHLFPIPLEVVLLPPTFFVSI
YDLSVYGRVNMIPLLLLGHKKFQLKTPATPSLKDLFLTREDRSEEHMWEEYRTKEYRSFF
SKLQTGVKTLIGYPDYLHSLALDSTKRFMLDRLEPDGTLYNYFGSTFFMIFALLSIGYSK
KDPVILKAIAGLKGMACSIEGHTHIQFTTPHVWNTSLISYALQESGIPSKDPTVKAANQY
LLSRQHYMYGDWLIHNPNAIPGGWGFSDFNTMNPDVDDTTASLRALAKQLQAKPDIWDSW
QRGVSFTISMQNDDGGFPAFERNNDHQWLHLLPIEGSKYLLTDPSTADLTGRTLEFLGNY
TNMKKPEEVSKRAVEWLLEDQKRDGSWYGRWGICYLYGTWAALTGMKAAGQATGHPSIQK
ALTWLKKIQNKDGGWGESCYSDIKQRYIPLGASTLTHTAWAVDALISASDRPTAEIEKGI
AYLIRAGQQESWTNDYPAGQGMADFLYIHYHSYRYIYPLLTLSHYNKKFLNT
>A0A7Y4UGQ6|squalene-hopene cyclase|EC 5.4.99.17|Acidobacteria bacterium|TrEMBL
SSTVPLLVVLDKRPVYDLSVDVPELFTDRDVSLKNNDGTLVGSLFLFADKSLKLLDRIGL
VPFRVAGHEAAERWVIERQDTPGDWAGIVPAMINSLLMFHVLGYAVNHPYLKRGLEALDR
FCIAEGQATGSEEPQYLRLQPCISPTWDTALGGSALLDSGLAKTHPRLQAAAEWLLTQQI
FRYGDWAIYNLKGKPAGWAFEFYNDYYPDVDDTAAVIMMLLDTKLPAEEKDEAKLAACRA
ATEWVMTMQCRAGGWAAFDIDNTQELWNQMPYGDLKAMIDPPTADLTGRVLEMLGHWQNK
LGEKLYRDEDLQRAMQFLLSLQEPDGAWWGRWGVNYIYGTYLALVGLRAIAPYANFDMQC
EAVQRAAAWLRSVQNADGGWGETCASYKRPELRGKGASTPSQTAWALLGLMAAGDVDSGA
VKQGIAYLLTTQNADGSWPEAEFTGTGFPGHFYINYHQYRNQFPLTALGRYAAATF
>A0A7S7TME9|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. CCBAU 51753|TrEMBL
MQNSISKATEALLGYRQADGHWVFELEADSTIPAEYILLRHYLAEPVDSALEAKIGNYLR
RVQGAHGGWPLVHDGPFDMSASVKSYFALKMIGDSVDAPHMVRAREAIRSRGGAAGSNVF
TRFLLALYGVVSWRATPVLPIEIMLLPMWSPFHINKISYWARTTMVPLMVLAALKPRAKN
PKGIGIDELFLEDPKSVRMAPKAPHQSASWFYLFRSLDAVLRVIEPMFPKSLRQRAIDAA
LAFTEERLNGEDGMGAIYPPMANIVMMYDALGKDESYPPRATTRRGLDKLLVIREQEAYC
QPCVSPVWDTALTCHALEEVGGDSFARAKEGLDWLKPRQVLELKGDWAVKAPNVRPGGWA
FQYNNDHYPDLDDTAVVVMAMDRVRRQTGTGEYDAAIARGREWIEGLQSRDGGWAAFDVN
NLEYYLNNIPFSDHGALLDPPTEDVTARCISMLGQLGETAATSKAMADGVAYLRRTQLAE
GSWYGRWGLNYIYGTWSVLSALNVAGIDRNDPMIRKAVDWLVSVQNQDGGWGEDAVSYRL
DYKGYEVAPSTSSQTAWALLGLMAAGEVEHPAVVRGVEYLKATQSEKGLWDEQRYTATGF
PRVFYLRYHGYSKFFPLWALARYRNLRSTNSRVVGVGM
>B1H4D0|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia pseudomallei S13|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGAVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A7G9P3M4|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetales bacterium zrk34|TrEMBL
MSSGTFVDSSTEGAAATPSLEAAPIDPALREATRKSLEAAMRELIRQQTGEGYWCAELEG
DSILQSEYILLKWVIEQEDDPKLEKIANYLRKQQRASDGAWIQYPGAKPDISATTKSYFA
LKLMGDDINAPHMVKARELILSLGGAEKCNTYTKFFLAALGQMHYDNVPAVPPEMVLLPK
WFYFHLDKVSAWSRTMIMPLSIVSSYRPVRQLPEPMGIMELYTNHDYLHRPLLEIDKKLV
SWKNLFYAADRGLKILEKIKLTPLRRKAIKQIEEWIIERTDHPHSDGLGAIFPGMVYIII
AFRCLGYNLDDTPVRNAMEELGRLMIEDGDDIRLQPCFSPIWDTGIAAYAMTETGMTASS
NQALSKAVDWLVSKECREVVGDWKNNVNHEVPPSGWYFEFNNAYYPDVDDTAMVAMALHR
AANGTAPHAAEAAKRGIDWIFAMQNEDGGWAAFDRTISRPILEHIPFADHNAIQDPSCPD
ITGRTLECLGHHGFSPDDPRVVKAVNFIRFEQEPEGCWFGRWGVNYIYGTWQVVCGLDRI
GIDMSQDWIQKAGLWLRSIQKPDGSFGESADSYEDLSTKGQGPSTASQTAWAVMAMMSIY
GPSDPGVMRGLNWLIETQLQADDPESGDRAGSWREDWFTGTGFPRVFYLRYHLYRLYFPV
MAMGRWLSAVDKK
>A0A494X784|squalene-hopene cyclase|EC 5.4.99.17|Pararobbsia silviterrae|TrEMBL
MPFGTPPAGAAAQPPDAAAPAHADLERGIAAARDALIDLQHDDGYWLFELEADATIPAEY
ILFVHFLGETPDLALEAKIVAYLKRIQGKHGGWPLFHDGRLDVSASVKAYFALKMAGESP
DAPHMRRAREAILAHGGANMSNVFTRAMLAMFGVVDWKAVPMMPVEIMLLPTWFPFHLSK
VSYWARTVIVPLLVLQTLRARARNPKGVTIDELFIGSPRDVGPTPRAGHQSRAWFTFFNI
ADTVLRATESLFPKRSRKKAIDAAVAFVDERLNGEDGLGAIFPAMVNSVMMYDLLGYPAD
HPNRAIARRSVDKLLAIQDDEAYCQPCLSPVWDTALTAHALIETGDARAIEHATRGLDWL
VPLQILDVRGDWISRRPDVRPGGWAFQFANPHYPDVDDTAVVAMAMDRAQRIHGDTRYDA
AIDRACEWVIGMQSSNGGWGAFEPENTHLYLNNIPFSDHGALLDPPTVDVSARCLSMLAQ
LPKHKERDASAELALKYLIDDQEKDGSWYGRWGLNYVYGTWSALCGLRAGGIEPGSPILE
RGAQWLLSIQNADGGWGEDCESYKLDYHGYEAFPSTSSQTAWALLGLMAAGYADHPALAR
GVRYLLDTQNADGLWDEALYTATGFPRVFYLRYHGYRKFFPLWALARYRNLTVRNACPIP
CGM
>A0A7X0M9R3|squalene-hopene cyclase|EC 5.4.99.17|Sphaerisporangium rubeum|TrEMBL
MTTTLSVGAGIAKAAEGLFARQRPDGSWEGFLPSSAVSTGSVIIALRVADPDASRELVAA
GASWLRSHQLADGGWGDTPEAPASLNATAIAVAALRLTDAAASEEAVAAGLARIEGFGGW
DAVADRRRCTLKAVCEQYLALAGLYPAERVGRMPFELALASSWLRRKLSFTVPGLMSWGV
MQSRTQRFGPLRRAVNRLAEPRALDYLADLHDHEGPDGAVEESALMASVVCLGLASAGAA
PGIVADYLRYLRGTVRPDGAWPVDRDIEFSVSMYLTHGLVDAGFGDDPRLRRTGEWIRAS
QRSRPFAPTGCPAGGWGWSLPSGWPDTDDTSCAVASLAALGAGADDSSLRRGTAWLLTMQ
NSDGSWGCFARNAKVSMDAPCSVMTSHAVLALHAAAGPPPAHGLGDDFAAPLARAVRWFG
KAQRADGSYPCIWFRDSTAGTARVLDALGRLGLGGTPTATRALTWLLGHQRSDGGWGDGG
SQPSSAEETAWAVLGLVSAGHADHPATGAGVRWLLDHQRADGLWDATRLGVYFLGLTYWC
DHIADGYALQALGRYRAATKE
>A0A4Q2U6Y2|squalene-hopene cyclase|EC 5.4.99.17|Lichenibacterium minor|TrEMBL
MSFAVHVADTAARPSPSAMTGLDAAIARAASALLDEQRADGHYAFDLEADAAIPAEYIMV
KHFLGESDPDMERRTANYLRRLQEPHGGWPMLAKGELNMSASVKSYFALKIAGDPVDAPH
MVRAREAILAHGGAVNMNIFTRMMLAFFDIVPWSAVPVMPVEMMHAPLWFPINIWRFSYW
ARDTVVPLLVLMAKKPRAANPRRVGIDELFHVPPHAVKRWPKTANQVGFWGAFFVGLDKA
LRVVEPMFPKRSRDSAIGKAVDFLTERLNGDDGVGAIYPSIAYTLMMFHVLGYPEDHPDM
IVARAALEKLVAQNGDEAFCQPCLSPIWDTVLAAHALLEAERDDSEGAERALDWLLPLQV
LDFKGDWAVRRPDLRPGGWAFQYKNDHYVDLDDTAVVVMAMDRTRNKSGTRRFDVAIERA
VEWVVGMQSTNGGWGAFDVDNTSYYLNHIPFADHGALLDPPTADVSARCLSMLGQLGYTA
DTSEAVRRGIDYLLKEQHPEGSWFGRWGVNYIYGTWSVLCAFNAVGVAPTHTAVRRGVDW
LLKIQNADGGWGEADAGYALDYVEYVPNESTASQTAWAVIGLMAAGEVDNPAVKRGVAYL
EKHQGEDGFWAEPHYTGTGFPRVFYLRYNGYAKFFPLWALSRYRNLRQGNTATVLHGM
>D5MHN5|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Methylomirabilis oxyfera|TrEMBL
MIRTVLPADGNPLDEAIEQARSRLLAMQDPAGYWAAELEADSTLTSEYIMLRYLLGKVDE
TKQRKAATYLRDTQLPDGGWNIYYGGPSHLSTTVKAYFALKLCGHSQAEPFMQRAREVIL
RQGGLFRANVFTKFTLALFGQFDWRGVPAMPIELFLLPQGSLFNMHAISYWSRTVLTPLM
IIFAHKPITPVPAGADLAELRVGDAPKHDYWFPRDPQPLARRNLFLAADRVLRWYEWHPI
SYFRRLAMERATAWMLRRMGEGGLGGIYPAMANSVIALRCLGYEVEHSLVARAFKQIEAL
EVEDERTLHVQPCFPPSWDTCLAVNALIASGLPTDHPALITACEWLLSKQTRTVADWKVK
APDAEPGGWYFQFENEFYPDVDDSAVVMTALIKTNLPDQAIKDAALAQALKWVLPMQSSD
GGWASYDKDNNKLFLNDIPFADHKALLDPPTSDLTGRMLEMLGHLGWSNAAPAAQRGIAF
LKREQEATGCWFGRWGVNYIYGTWSVLAGLRAIGERMDQPYIRRAVDWLISHQNPDGGWG
ESCHSYEDPRTAGQGPSTASQTAWALLGLLHAGVVRHPAVKKGIDYLLRTQGADGDWEER
EFTGTGFPRVFYLRYHLYRLYFPLWALSLYRTLLQKAAAGHDDNGAPLPDPHGR
>A0A537ASB5|squalene-hopene cyclase|EC 5.4.99.17|Betaproteobacteria bacterium|TrEMBL
MSAHLAEPKAGLVSPGLAPRSLQQAIDQATRALLDQQRADGHFVFELEADSTIPAEYVLL
VHWLGETPDLQLERKIAAYLRRKQGENGGWPLFEGGRFNISASVKAYFALKMIGDDPGAP
HMVRAREAILAHGGAARTNVFTRTLLALYGAIPWRSVPVMPVEILLLPRWFPFHIAKISY
WGRTVLVPLTVLNALRPLARNPRQVVIPELFCTPPEVVHRWPKGEHHRFPWSQIFRAIDR
VLQVIEPHFPTGLRQRAIQEAVQFTTERLNGVDGLGAIFPAMANSVMMFDALGYRADHPD
RAAARRSVDRLLLIKDDEAYCQPCVSPVWDTGLAVHALLEVGSDEAVTRAGRGLQWLQPR
QVLDTVGDWAMTRPRVRPGGWAFQYNNPHYPDIDDTAVVLMAMDRAIREARLPDGADFDQ
AIARGVEWVLGMQSRDGGFGAFDADNDCEYLNHIPFSDHGALLDPPTADVTARCVSLLAQ
LEPAAGRARALRRALRFLRRTQEPDGSWYGRWGMNYIYGTWSALCALGAAGIDQNAPEVQ
RAVHWLESIQNPDFGWGEDGESYRLKYRGYEPASSTASQTAWALLGLMAAGRVDDPAVER
GIRYLQRTQGADGLWPETRFTATGFPRVFYLRYHGYAKFFPLWALARYRNLKAASSRSTW
LGM
>A0A7C5PGT0|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia bacterium|TrEMBL
MLNRQIDYDLGGLAERLDEAIAAAQEWLLASQAEDGHWCAELEGDTILESEYLIYLHFID
RLDPVKLRKAANYIRAKMLPTGGWAIYPTGPLEISASVKAYLALKMAGDPAAAPHMIKCR
DAILAAGGITATNTWTKIYLAMVGLYPWDGCPAIPPELMLLPKWFSFSIYNMSSWSRAMF
VPLAIIRSLEPVKPLPVTAQLDELWVGGKEHADIHLPRDARYFTWRNFFLTWDTILKFLH
RHHPSTLVRTAAMRKAERWTIEHGRVPGGLGAIFPAMANYVLALRVLGYTNDSFLVAQGI
REMESLEIEDEDTLRLEPCFSPVWDTAISVNALHEAGLPSHHPALVQAARWLLDKEVRRP
GDWRIKHSESHRYTEPNKPVGAWFFEYDNEFYPDVDDTIMVLMALNRVQTPFDREKSAAI
RRGIRWVLGMQCSDGGWAAFDRDNDKWIFTQVPFADHNAMIDPATSDITARTLESLAHFG
FTLEDECVQRALAFLRRDQCPDGSWFGRWGTNYIYGTWQVLRGLRTIGEDMRLPYVRRAV
AWLKFTQNADGGWGETVRSYDDPKYKGIGESTASQTAWALMGLLSAGEADAPEVQRGIEF
LVRTQTEEGTWNEALFTGTGFPKVFYLRYHHYRHYFPLMALGMYARQKFHNFPPVPREQE
KSRALQKFFEQPRLYRKVARLRALTMRREDE
>A0A522AN08|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia bacterium|TrEMBL
MSVSTETSRSVRPSELAEPGKHSWPELQAAIARSQNYLFSLQKPEGFWVGELMVDSTLVS
DTVAYHHWNGKIDPAWQRKAVNHIFSMQLPDGGWNIYYGGPSEVNATIKAYLALKLAGVP
VTDPRMLKAREVALNFGGVPRMNTFSKLYLALLGLFPWEYVPTIPCEVLLIGKWFHVNFW
DMSNWSRGMIVPLSIINHFKPTRPPKNNVNLDELYPAGIHERDLALAPDPERITLRNFFL
WLDRLHKFAEWFAENNIHPFRKLALKKAERWMLERFEGSDGLAAIFPAMLNSLIALKALG
YVDDHPQVQRAEHELKKLEHETENSVRIEPCFSPVWDTAIVLVCMRESGVSETDPRMKRA
AEWLMEKEIRFRGDWQYKNPAKVEASGWVFEYNNKWNPDVDDTAMVLLALRKIPTDNPKK
RDECFQRGLKWMMTFQCKDGGWAAFDKDCTKNILEKVPFADHNAMLDPECADITARILEL
LGYEGWDKNHPQIKDALHYVRSQQEEDGSWYGRWGVNYIYGTWQVLRGLWALGLDMNQPW
LLKGKRWLESVQHADGGWGERCNTYDDPVFKGQGPSTASQTAWAVMGLCTFGDPDLPSLK
RGIEYLIRTQNADGSWTEDEITGTGFPKVFYLKYDMYRNAWPLLAFASYNQLLQRRAEKS
SAEVNGRSFDLAQEPALKQNSAGQSAR
>A0A7Y4QI60|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia bacterium|TrEMBL
MGVSVATDTARFGTSPQETSPEIAVWPEFDAALRRSQNYLLSIQKPEGYWVGELMVDSTL
VSDTIAYHHWNGKVDERWQRKAVNHIFSMQLPDGGWNIYHGGPAEVNATIKAYLALKLAG
VTVTDSRMLKAREMALNLGGVPRMNTFSKLYLALLGLYPWKYVPTIPCEVLLIGKWFHVN
FWDMSNWSRAMLVPLAIINHFKPTRPPKNNVNLDELYPHGFHERDLALAPDPDKISLRNF
FLWLDRLHKFAEVFAQNGIHPFRKSALKKCENWMLERFEGSDGLAAIFPAMLNSLIALKA
LGYADDHPEVLRAERELKRLEHEDATSVRIEPCFSPVWDTAIVTICLRESGISSDHPKLK
RAAEWLMEKEIRFKGDWIHKNPAKVEPSGWVFEYSNTWNPDVDDTAMVLLALRQVPTDNP
AKRDECFQRGLKWMMTFQCKDGGWAAFDKDCTKNILEKVPFADHNAMLDPECADITARIL
ELLGYEGWSASNRQVADGLDYIRRQQEADGSWYGRWGVNYIYGTWQVLRGLAAMKIDMNQ
TWILKGRDWLESVQHVDGGWGERCNTYDDPVFKGRGPSTASQTAWALMGLLACGDPSRAS
IRRGFEYLIRTQNADGSWTEDEITGTGFPKVFYLKYDMYRNAWPLLAFATHRQLIERKQP
GTRPEVDRDLQTMTSAALNGNGHFAAATRTETR
>A0A5C8X1S9|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium sp. WL8|TrEMBL
MREAVNKVEALQRPKTQAISLDDVDHGVARATRALTALSHDDGHICFELEADATIPSEYI
LFHQFRDTKPPEGLEPKIGNYLRRTQEKHGGWALVHEGPFDMSCTVKAYFALKMIGDDIE
APHMRRAREAILSRGGAAQSNVFTRFILALYGEVPWAAVPVMPVEVMFLPKWFPFHLDKV
SYWARCVMVPLFVLQATKPLAKNPRGIGIGELFLTPPSSVRRWPGSPHATWPWTPIFGGI
DRILQKVEGHFPKRIRLRAMEKARAWVSERLNGEHGLGAIFPAMVNTVLMYEAMGYGPDH
PQVRVACDAIEKLVVVKAHEAYVQPCVSPVWDTALAGHALLEAGGTDAEGQARAGLDWLL
PRQVLDIAGDWAAAKPKVRPGGWAFQYANAHYPDLDDTAVVVMAMDRAMRQHGLVANMPD
YTASIARAREWVEGLQSKDGGWAAFDADNNHMYLNHIPFSDHGALLDPPTADVTARVVSM
LSQLGETRESSKALDRGVTYLLNDQEQDGSWYGRWGMNFIYGTWSVLCALNAAGVDPQSP
EIRRSVEWLIRIQNPDGGWGEDASSYKIDPAFEAGSSTASQTAWALLALMAAGECDDPAV
TRGINFLARTQGADGFWNEERYTATGFPRVFYLRYHGYPKFFPLWAMARYRNLKRGNSRQ
VAYGM
>A0A845YE98|squalene-hopene cyclase|EC 5.4.99.17|Symploca sp. SIO2G7|TrEMBL
MQTQDRITTKSTLAEAIAKAHNYLLDLQYPEGYWWAELESNVTITSEVVLLHKIWGTDQT
RPLHKVEAYLRSQQREHGGWELYYGDGGHLSTSVEAYMALKLLGVPATDPALLKAKKFIL
ERGGISKTRIFTKFHLALIGCYDWRGVPSIPPWVMLLPEQFLFNIYEMSSWARGSTVPLL
IVFDHKPVYQTNPAITLDELYTEGASNVQFELPRHGDWTDLFVVLDDAFKLAEDWKVVPF
RQEGLEAAERWVLERQEVTGDWGGIIPAMLNSLLALRSLDYDVADPIVVRGLKAVDNFAI
ETAETYLIQPCISPVWDTAWVMRALVDSGVAPDHPALVQAGEWLLSKQILDYGDWAIKNR
QGKPGGWAFEFENRFYPDLDDSAVVVMALDAVQLPQEDQKQAAIARAVAWIASMQCQEGG
WAAFDLNNDADWLNYLPYADLKAMIDPNTADVTARVLEMLGSCNLSIDKGKLERSLAYLL
EEQEADGSWFGRWGVNYIYGTSGALSALSVIAPQRHRLSIQRGVTWLVGCQNADGGWGET
CRSYDDPTLKGQGHSTASQTAWALIGLIAAGEASDNWKTEAINQGINYLVTTQLPDGSWQ
EDYFTGTGFPSHFYLKYHFYQQYFPLIALGRYLK
>A0A522A9V9|squalene-hopene cyclase|EC 5.4.99.17|Rhodospirillaceae bacterium|TrEMBL
MTISISPAKTSTGSGPSAAALDQAIGEATAALKRRQREDGHWVYDLEADATIPAEYIMLN
HFLDEIEDSVEAELADYLRAIQGENGGWPLFHGGDVDISATVKAYYALKLVGDDPEAPHM
HRARDAILAGGGAERTNVFTRYALALFGQVPWRAVPVMPVELAIAPRWFPITLYRMSYWS
RTVVAPLLILAALKPVAKNPRGVTIRELFRRSPEQIRDWHRNPTGHPIGTFFLLLDKVLR
VIEPRVPSFIRKRAINKAVAFFRERLNGEDGLGAIFPAMANAVMAMEVLGYPKDHADLVV
AKLAVKKLLTKGEGKTFCQPCVSPIWDTGLAAHALMESGESIDAPMVRDSCEWLKQRQVL
DVVGDWAEKRPGLRPGGWAFQYNNAHYPDVDDTAVVAMALHRADGKTYQEPVARAVEWVI
GMQSSDGGWGAFDIDNNSSYLNHMPFADHGALLDPSTADVSARCLSFLAQTGHERTHPTV
VRGIEYLKREQEADGSWFGRWGTNYIYGAWSVLCALNAAGEDMGQAYIRKSVDWLLACQR
DDGGWGEDGATYWNERRGEVKESTPSQTAWAVLGLMAAGEVDHPAVKRGIDFLLAAPREA
DGRWREPWFTAVGFPRVFYLRYHSYAAVFPLWALARYRNLRASNTKAVRYGM
>A0A8I1DKA7|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cepacia|TrEMBL
MIRRMTQSTLSPWSALDTAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDLRQERMARYLRANQRLDTHGGWALYVDGDPDVSCSVKAYFALKAAGDSEHAPHMVRA
RDAILKLGGAARSNVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNVSIRELFVTPPDEERRYFPPARGMRKLFLALDRTVRHVEPL
MPKGLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMQVLGYPDDHPLRRDCENAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVAVPEDGEPDDARRALDARIARAY
DWLAERQVNDLRGDWIENAPADVQPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRTHRNA
DGTNPYATRVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRADERASLARCIEYVKRTQQPDGSWWGRWGTNYIYGTWSVLAGLALAGED
KSQPYIARAIEWLRSRQHADGGWGETNDSYIDPKLGGTNGGESTSNFTAWALLAQMAFGD
CESDSVKRGIAYLQSVQQEDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GAAAAAPAAVDAADTAVA
>A0A5J6U4F5|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. WMMB 499|TrEMBL
MTTTEPIHPAPEQAAPERAAAEAAGAMRTPAEALAAAREHLLALQSPEGWWKGELQTNVT
MDAEDLLLREFLGVRTEDDTRETARWIRSQQAEDGTWATFHGGPSDLSTTAEAYVALRLA
GDAPDEPHMARASAFVRARGGVPETRVFTRFWLAMFGEWSWDDLPVLPPEMMFLPRWFPL
NVYDFACWARQTIVPLTIVGSLRPVRPLPFDLPELRAEHPARRSGRRRVPGWDEAFHTLD
RALHVYERRPVRALRQAALRRAGEWIVARQEADGCWGGIQPPWVYSLIALHLLGYRNDHP
VMKRGLDGLERFTIRDAKGRRLEACQSPVWDTVLAMNALADAGVPGDDPAQRRAADWVLG
EEVTGPGDWSVRRPNLPPGGWAFEFDNDVYPDTDDTAEAILALDRVGHPAAEPAIERAVR
WMAGMASADGGFAAFDADNTRELCRRLPFCDFGEVIDPPSADVTAHVVEALARRGMADSR
TVKRAVVWLLRAQERDGSWFGRWGANHVYGTGAVVPALIAAGVRPGKPAIRRAVRWLERH
QRPDGGWGEDLRSYDDPGWIGRGASTPSQTAWALLALLAAGERGPAVDRGVRWLIEHQRQ
DGTWDEDHFTGTGFPGDFYINYHLYRLVFPVSALGRYVREA
>A0A832HPU8|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MGNRVVAKQLTNVGSETAVNLNSVAELGTAIRRSQEHLLSLQKPDGYWIGELMVDCTLVA
DMIAYHHWDGSVDPKWQEKAVRHLLSLQLPGGGWNIYYGGPPEVNATIKAYLALKLAGMK
ETDPHLLKARSVALALGGVPRMNTFSKLYLALLGLFPWKYVPTIPCEVLLIGKWFHVNFW
EMSNWSRAMLVPLAIINHFKPTRPIPNISLDELYPEGYHERDLRLPRDPQLITARNFFLA
LDKLHKFAELWAQAGIHPFRKRALKKAEEWMIERCEGSDGLGAIFPAMLNSLIAFKALGY
PNDHPYVKRAEQKLKELEHETDTTVRIEPCLSPVWDTAIVTIALRASGIPANDPRIEKAT
EWLINKEIRFRGDWYHKNPAPVEPSGWAFEFENKWNPDVDDTAMVLLALRLVPTKDPARR
DAAYKRGLNWMLTFQCKDGGWAAFDKDCTKNILTKVPFADHNAMLDPECADITARILEVL
GHEHFPLDHPQVSKALNYIRSQQEPDGSWFGRWGVNYIYGTWQVLRGLSVLGVNMNEPWL
LKARDWLESVQHEDGGWGERCDTYEDPVFKGRGPSTASQTAWAVMGLCAFGDPNRESLVR
GVEYLIRTQNPDGSWTEDETTGTGFPKVFYLKYDMYRNAWPLLALATYRDLVAKSKAS
>A0A7C2JF21|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MRSVRAAGSRHRPPAAGGAWRSLVGCEPGQGRCRSVALRPRLLADVGREDAVSARPLYHD
RQLLAEAVRDAVRRSQDYFLRTQHPEGYWWGELESNVTMAAEYLMLTHILGVADAERWRK
VANYLRREARPDGTWAIYYGGPPDLNATVESYLALKMAGAPADDPLLEKARAFVLSRGGV
PRVRVFTKIWLAMLGLWDWRGVPVLPPEFMFLPTWFPINLYEFASWARATIVPILIILDR
RPVWPVPQHARIDELFPVPPSHLDYRLPPPQRLLSWKGLFWGLDHALRAYGRVAFRPLRE
AAIREAVKWIIARQEADGSWSGIQPPWVYSLIALKLLGYPLEHPVMRKGLEAFEGAFRVE
DDTVYYPQACISPVWDTALAMIGLLDSGLPPDHEALVRAGRWLLKEQIFTGGDWQFKAKG
VEPGGWAFEFDNDIYPDVDDTAEVMMALHRTRLPEEGRKARALRRGLEWVLGMQCRDGGW
GAFDKDNTQRIITHIPFCDFGEVLDYPTEDVTAHVVEMLGLLGYRADFPPVRRALAFLRR
KQDADGPWWGRWGVNYIYGTGAVLPALQAIGEDMRRPYVRRAVRWLLDRQNADGGWGESC
DSYADVSLKGQGPSTASQTAWALMALLAAAADDPDGEAWESIGRGAAYLVETQEEDGTWH
EPYFTGTGFPRDFYINYHLYRNYWPLMALGRLHRLLST
>A0A7C2YSH8|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MSAGPLYRDRQRLAQAVREAVERSRDYFLRTQHPDGYWWGELESNVTMAAEYLMLTHILG
VADPERWRKVANYLRREARPDGTWSIYYGGPPDLNATVESYFALKMAGVPADDPLLQKAR
EFVLSRGGVPRVRVFTKIWLAMLGQWDWRGVPVLPPEFMFLPTWFPINLYEFASWARATI
VPILIILDRRPVWPVPEHARIDELFPVPPSQVDYRLPPPQRLLSWKGLFWGLDHALRAYG
RVAFRPLREAAIRQAVKWIIARQEADGAWSGIQPPWVYSLIALKLLGYPLDHPVMKKGLE
AFEGSFRVEDDVVYYPQACISPVWDTALAMIGLLDAGLPPDHEALVRAGRWLLKEQIFTG
GDWQFKAKGVEPGGWAFEFDNDIYPDVDDTAEVMMALHRTRLPEERRKAMALARGLEWVL
GMQCRDGGWGAFDKDNTQRLITHIPFCDFGEVLDYPTEDVTAHVLEMLGLLGYGPDFPPA
RRALAFLRRKQDPDGPWWGRWGVNYIYGTGAVLPALRAIGEDMGRPYVRRAVRWLLSCQN
TDGGWGESCHSYDDPSWKGRGESTASQTAWALMALLAALPEAEDDALREAVARGATFLVE
TQEEDGTWREPQFTGTGFPRDFYINYHLYRNYWPLMALGRLQRLLGI
>A0A535UN94|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MGTALVTAAAVPLPARPPRAGSLAPEAERLDRACERARDGLLAQQRADGHWSYRLQSNVC
MEAEYLLLGRILGRADPDRERRLIARILDDQLPDGGFPTYAAGPADADVTVEALAALRAA
GLPSGHPRVAAARAAAERLGGVAATRVFTRMWLACAGLRPWEGLPELPPEMLFLPGRGPL
GLMRFASWARATIVPLTVVLTLRPQCDAVVLEPGALPEGAPGGPRRPVPSGPLASAFLGI
DRVLAAYRRLPHQPGRGRALARAEAWIVDHQDVDGAIGAIQPPMAYQCLALHALGHRRGS
PALERAWSAFEGFVLDDGERCEMQACVSPVWDTALAMCALADLGVAPDDEAMRRAARWLL
AEEVRVRGDWARTRPHLPAGGWAFEYHNDLYPDVDDTAIVLCALGGADVEGRDDAVLRGL
RWMLGMRCRDGGVAAFDAENTSRLVGRIPFCDFGAVTDPPSADVTAHVLEAAARWGLSAT
HRDVTAMRAWLLRHQESGGSWFGRWGVNHVYGTAAAIPGLTAAGLHRLHPAVQRGVAWLL
RVQREDGSFGEDCGSYRDPALIGRGEPTASQTAWGLQGLCSGGEAGSGAAARAARWLVEQ
QGADGLWSDSRFTGTGFPGDFYLGYHGYAAYFPAAALGRYRRSRPVGGAHSTGRAPIKLT
GALSEALV
>A0A7Y3LWX1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. S3(2020)|TrEMBL
MTATTDGSTGALPPRAAAASETDIETPAATGVQEAAVRAVQRATEHLLARQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDESTTRAAGLFIRGEQREDGTWASFYGGPGELSTTIEAY
VALRLAGDAPDEPHMARASEWIRARGGIASARVFTRIWLALFGWWKWEDLPELPPELIYF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPANPNPAKPLAPAASW
DGAFQRLDKALHQVRKVVPRRLRKAAMNTAARWIIERQENDGCWGGIQPPAVYSVIALHL
VGYDLEHPVIRAGLESLDRFAIWREDGARMIEACQSPVWDTCLATIALADAGVPADHPQL
VRAADWMLGEEIVRPGDWAVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHDP
DRVENAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIEWLLAEQEQDGSWFGRWGVNYVYGTGSVVPALTAAGIPAAHP
AIRRAVRWLESVQNDDGGWGEDLRSYQEAKAWSGRGASTASQTAWALMALLAAGEKDSKA
VERGVEWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFAEA
GEA
>A0A1D3RMU7|squalene-hopene cyclase|EC 5.4.99.17|methanotrophic endosymbiont of Bathymodiolus azoricus|TrEMBL
MAAGETDTQEVKAGISYLLNSQTEEGVWADECHTAPGFPRVFYLKYHGYDKFFPLWALAR
YRNEQNKT
>A4Z167|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. (strain ORS 278)|TrEMBL
MTLTSSASARAPRDPGNYQTALQSTVRAAADWLIANQKPDGHWVGRAESNACMEAQWCLA
LWFMGLEDHPLRKRLGQSLLDTQRPDGAWQVYFNAPNGDINATVEAYAALRSLGYPDSEP
AVRRAREWIEAKGGLRNIRVFTRYWLALIGEWPWEKTPNIPPEVIWFPLWFPFSIYNFAQ
WARATLMPIALLSARRPSRPLPPENRLDTLFPRGRDAFDYELPVKANAGGWDKFFRGADK
VLHALQNFGNRLNLGLFRPAATSRVLEWMIRHQDFDGAWGGIQPPWIYGLMALYAEGYPL
NHPVLAKGLDALNDPGWRVDVGEATYIQATNSPVWDTILTLLAFDDAGVLGDYPDAVDKA
VNWVLARQVRVPGDWSMKLPHVKPGGWAFEYANNHYPDTDDTAVALIALAPLRHDPKWKA
KGIDEAIQLGVDWLIGMQSQGGGWGAFDKDNNQQILTKIPFCDYGEALDPPSVDVTAHIV
EAFGKLGISRNHPSMVQALDYIRKEQEPSGPWFGRWGVNYVYGTGAVLPALAAIGEDMTQ
PYIGRACDWLVAHQQPDGGWGESCASYMDISAVGRGTTTASQTAWALMALLAANRPQDKD
AIERGCMWLVERQSAGTWDEPEFTGTGFPGYGVGQTIKLTDPSLQERLMQGPELSRAFML
RYGMYRHYFPLMALGRALRPQGHG
>A0A849RNS3|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp|TrEMBL
MKLFRTLFDRLSSSLLATIPGKYNPAVEYTQTPPLRLVSDKVPPLAATDSSRRPSAHTVS
QPDAIDDAIRRSQSWFLSKQDPAEGFWVAELEADTTLTSEYLMLRRFLDCVDPVKEERAV
RYLRTMQLPDGGWPIYYGGPAEISASVKAYFALKLSGIPASDPCLLRARERIMAMGGVVQ
ANVFTKIALALFDQYDWEGVPHMPVEIMLLPKRFYFSIYAISYWSRAVLIPLLIVFAHQP
VCRIPREQGIEELYLVPRGQVPYWKYPPFNKDQAWFTPHNFFVMLDAVLKLYDRMPLLWL
REKAMHKAATWMLDHLKGNGGLGAIYPAMANSVLALRCLGYEMDDPLVQKALREIEDLEV
HETATVDGQRVPTLHLQPCHSPIWDTALLMNALIEAGMPQDHPALVKAGAYLMSRQTKMV
GDWTISSPQAEPGGWYFQFENELYPDVDDSAVVLMALAKLKMPEPADLRESIRRGMQWVL
AMQSSDGGWGAYDKDNNRVVFNYIPFADHKALLDPSTADLAGRCLEMLGALGYDRFHPAV
QPALAFLKKQQEADGSWYGRWGVNYIYGTWSVLAGLRAIGEDVSSPYIRRAVSWLESKQN
PDGGWGEACLSYAEEAHSGKGQSTPSQTAWALMALMSAGVTESLSIARGVQFLLRHQLKD
GSWEEVMHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRSRGRMRAEELREQVESSGCY
RFDH
>A0A5D0UXW0|squalene-hopene cyclase|EC 5.4.99.17|Micromonospora sp. MP36|TrEMBL
MTELLSPKPKPTAIATRPGATASDPAWEALRRARDHLLGLQDDAGWWKGNLATNVTMDAE
DLLLRQFLGIRTAEQTAESARWIRSQQRPDGSWATFHGGPGDLSTTVEAYLALRLAGDTP
DAPHLAAAARFVRAHGGLAASRVFTRFWLALFGHWPWSQLPAVPPELVLLPHWMPFNVYD
FACWARQTIVPLSIVRALRPVRELGFDVDELRTPAAAPRPPRLRSRAGVLHRLDRLASGY
ERIARGPARRHALRRAAEWIVARQEADGSWGGIQPPWVYSLMALHLLGYPLDHPVLRAGL
DGLDRFTVREQTPDGPVRWLEACQSPVWDTALAVTALSDAGLPAGHPALERAGKWLLQEE
IRVRGDWAIRRPAAPVGGWAFEFENDGYADTDDTAEVIMALRRTAVPAEGAVLRGSRWLL
GMQCRDGGWAAFDADNTRAIVGDLPFCDFGEVIDPPSADVTAHVVEALAAENFAGTPPVR
RGVHWLLRAQEPDGSWFGRWGANHVYGTGAVVPALVAAGVKPGHPAIRAAVDWLLAHQNP
DGGWGEDMRSYRDPSWIGRGESTASQTAWALLALHAAGHGSGEPAQRGMRWLVDTQRPDG
GWDEPHYTGTGFPGDFYINYGMYRLVFPISALGRILNARGGLTAEVVP
>B1KBR4|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cenocepacia (strain MC0-3)|TrEMBL
MIRRMNKSAPSPWSALDAAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDR
IDDVRQERMARYLRANQRLDTHGAWDLYVDGAPDVSCSVKAYFALKAAGDSEHAPHMIRA
RDAILKLGGAARSNVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNVSIRELFVTPPEQERHYFLPARGMRRLFLALDRTVRPIEPL
LPKRLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMQVLGYPDDHPLRRDCENAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVAAPETGDTASGALRELDERIARA
YDWLATRQVNDLRGDWIENAPADVEPGGWAFQYANPYYPDIDDTALVTAMLDRRGRTHRG
ADGTHPYASRVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVS
GRVLLCFGVTKRAADRASLAHAIDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALAGE
DKSQPYITRALDWLRARQHADGGWGETNDSYIDPKLAGTNDGESTSNCTAWALLAQMAFG
DCESDSVKRGIAYLQSVQQEDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRL
AGAKDADATRSPASATPATDNALA
>A0A6P0NRT7|squalene-hopene cyclase|EC 5.4.99.17|Okeania sp. SIO2C2|TrEMBL
MTEKNKVQQSILASQEYLLNLQKPQGYWWDELESNVTITAEIVLLHKIWQTDKKRPLDKA
KNYLISQQREHGGWELFYGDGGDLSTSIEAYMGLRLLGVAKTDQIMLKAQDFIIKKGGIS
CSRIFTKLHLALIGCFNWQGIPSIPPSIMLLPEDFPFTIYEMSSWARSSTVPLLIVFDKK
PIFSVNPTINLDELYAEGINNASFELPRQYDLTDLFLGLDKAFKFAENFNLMPLREEGLK
AAEKWILSRQEVTGDWGGIIPAMLNSMLALRCLEYDVADPVVVRGLEAIDRFGIETEDSY
WVQPCVSPVWDTAWVIRSLVDSGIPPSHPAVVKGGEWLLQQQILDYGDWAIKNKLGKPGG
WAFELINRFYPDIDDTAVVVMALDALELPDEELKGQAIARAMEWVASMQCQPGGWAAFDV
DNDQDWLNGIPYGDLKAMIDPNTADVTARVLEMVGCCRLSMDSWRVKRAIAYLEREQEGE
GCWFGRWGVNYIYGTSGVISALAVVAGESHRGFIEKGASWLVGCQNSDGGWGESCRSYND
PSLKGMGKSTASQTAWALIGLLAAGEATGNFAREAIDRGVDFLVSTQNDDGSWLESEFTG
TGFPCHFYIKYHFYPQYFPLMALGRYENLLSG
>A0A7V3RRE3|squalene-hopene cyclase|EC 5.4.99.17|Gemmataceae bacterium|TrEMBL
MPPLSTRSASKDSSRRSSPLYRAMERACHCLLDKQQADGHWVGELQGDTILESEYILLMA
FLGREEEDVCRKAANYLLQQQMPEGGWNNYPGGPADLSVSVKAYFALKLTGHDAEAPYMR
RAREVIRSLGGAAGCNSFTKFYLALLGQFPYANCASVPPEMVLLPRWFYINLYAMSSWTR
TIVVPLSIFSACKPIRRLPAQKGIAELFLQAPDTPLWPAKPSGRLLSWTNFFLGVDWLYK
RIEPWLGPIRRLALKRAAAWMCEHLQESDGLGAIFPPMVYTVIAFRCLGVRDDAPEMQWA
LAQLSALMIEEEDTLRLQPCFSPVWDTALTVNALADAAPLLASLHLEEGKVREAIQRAIQ
WLLTKEVRRKGDWSLTNPGLEPGGWFFEYRNAFYPDIDDTAMVLMALAKTGEADTPHGRP
AVERGLRWLLGMQNSDGGWAAFDRDINREVLTRVPFADHNAMLDPSCPDITARVLEALGH
YGFGIDHPRVRRALDFLRKTQDARGCWIGRWGVNYLYGTWQVLCGLSSIGFDMEDGMVRR
AVAWLQKVQQPGGGWGETCRSYDDPTLAGQGAPTASQTAWALLALLAAGEGDSDAVRTGI
AYLLHTQDANGNWCEGPFTGTGFPKVFYLKYHLYRLYFPLMALARYQQMVGSSAAVFSYQ
FPPDE
>A0A094YJL9|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter tropicalis|TrEMBL
MAADGSAFSDAPVSKETLDRAVTNAHAALGKRQQADGHWVYELEADATIPAEYVLLEHYL
DRIDDALEQKIGNYLRRIQSKDHGGWPLYHNGKFDLSASVKAYFALKAVGDDINAPHMRR
AREAILDHGGAERTNVFTRCQLALFGDAPWRATPVMPVELMLLPRKAFFSVWNMSYWSRT
VVAPLLVLAALKPIAINPRQIHVRELFVTPPEVVKDWIRGPYRSVWGRVFKGLDTVLRPV
LPFIPTKTHDKAIKAAVDFIEPRLNGEDGLGAIYPAMANVVMMYRALGVPDEDPRAVTAW
KAVQKLLVIKDDEAYCQPCVSPIWDTGLSGHAMLEAASGPNGVAPEETLTELRKASAWLR
DKQILDVKGDWAINKPDLAPGGWAFQYGNDYYPDVDDTAVVGMLLHREGDPANAEALERA
RQWIIGMQSTNGGWGAFDIDNNKDLLNHIPFADHGALLDPPTADVTARCISFLAQLGHVE
DQAVIDRAIEYLRKDQEEDGSWFGRWGTNYIYGTWSVLCAFNAAGISHDDPAVVKAVEWL
RSVQGADGGWGEGCESYEGGAHGTYGESLPSQTAWATLGLMAAGRRDDPAVAKGMAWLAE
QQDENGEWHEDPYNAVGFPKVFYLRYHGYKQFFPLMALARYRNLESSNSRRVAFGF
>A0A534UGN9|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MAPPFLTTRHAEKKRIESSDELRPAELERAIRDAADALHELQHPQGYWCFELEADCTIPA
EYILMMHYMDEIDEQLEKKLASYLRARQRQDGGWPLYYGGNAEISCSVKTYYALKLAGDA
PDAPHMAKARETILRLGGASRSNVFTRITLAIFEQLPWRAVPFLPVEIMLLPRWFPFHLC
KVSYWARTVMVPLFLLYTFKARARNPKKVSIRELFTTDPWEQKGYFPVHSALNRVFLVLD
RLGLSLYPWILRGWQRCAIKKAEAWILARLNGESGLGAIFPAMVNAYEALDLLGYAFDHP
LRVQARRALENLLVDNGDSAYCQPCVSPVWDTAWACIALQQISEERSGTATKRAFAWFAE
RQLMKESQDWSFNRPHVRGGGWPFQFENSYYPDLDDTAAVAYAMHKSGDSKLSAAVERAA
EWICGMQSKNGGFASFDADNDHTYLNEIPFADHGALLDPPTEDVSARCAMLLAQRPSAQS
QVALERSLEYLFRCQEPDGSWYGRWGTNYIYGTWSVLMGLEEARVGIDAETIRRAAGWLK
QVQRPDGGWGETNDTYFEPSRRGRADRSTSFHTAWALLGLMSSGEVGSDSVRRGIDFLIR
TQQPNGFWNDPEFNAPGFPRVFFLKYHGYDKYFPLLALGRYRDLTARERK
>A0A534W4K5|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MVRGACPSWTARGFVIVSESKVGHSALDLVIERAQAWFAAEQFADGFWWAELESNATMDA
EYLLLTWFLGARDEQRWVGVAQDIRNYQRADGSWAMYHGAPGDLSTTIECYFALKLAGDR
ADAPHLSRARDFIRERGGIAAARTFTRIWLALFGQWSWDDLPVMPPELMLLPAGAPLSIY
RFSSWARGTIVPLLLLMDDRPVRPIPESARLDELHVEGAAARPPRDNLDRILFALDRALR
YYGRLPVHPLRRRARKLAEEWILAHQEADGSWGGIQPPWVYSLMALHTLGHPLDHPALKK
GLDGMHGRWMIRRDDGSLRVQACLSPVWDTGLALLALLESGADPSQPSLRKASQWLLREE
IRVPGDWCVQVQGIEPSGWAFEFENDLYPDVDDTAVVLLALQKAGAGDEETRERALRWVL
AMQSRNGGWAAFDKDNTSRLPALLPFCDFGEVIDPPSADVTAHVVEMLGAVLPALAAAGE
DLEGLAGRRAVRWLEDRQNPDGGWGETCASYVDAAVRGRGESTPSQTAWALLGLIAAGRA
DTQSAHRGARWLLERQRPDGAWDEDSFTGCGFPGYGIGEERGARISEGRELSAGFMIRYH
LYRNCFPLLALGRYRAAVRASGRPSPSQRGTACDRRSSTSAISMR
>A0A7X8CBP7|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MAILSKNKFEQDKPAVSEGKDSFWKDRPVEIAGERIRLQATQACLHSGGIEGSSVARIRK
AVDSTCDFFLRTQYAEGYWWSELESNVTITAEYLLLLRLIECADHGMERDIVRYLLSQQN
ENGAWGLYYGDEGDLSTTIEAYFALKLAGEDPESPPLRRARGFILRRGGIERSRVFTKIW
LALFGQYDWQKVPSMPVELVLLPSHFYFSIYELSSWARATVVPLSIVLTARPVYTLPESK
NVQELYLPSNGSPMRFKSWVHKLFFIFDRIAKEFEKRPFRRLRSRAIREAEKWILDHQEE
SGDWGGIQPPMVYSILALHYLGYPLDHPAMVKGMHAIKGFCLKDDQGLRMQSCISPVWDT
TLTTLALIEAGISPEHPAIRNAVSWLASKQTTTGGDWQVKSCCPPGGWAFEFVNTRYPDV
DDSAFVLTTLHRASQSGCDKLHEVKMRGMEWCLGMQSSSGGWGAFDRDNDMIILNRIPFA
DQEAMVDYPSVDVTGRVLEAMGHYGYPPTHPQAQRGIQFIRRMQEPDGSWWGRWGVNYIY
GTWAALRGLIAIGEDPGAAYIQAAVSWLKAHQNPDGGWGETCESYMNPDLRGRGTSTPSQ
TAWALMGLMACGEEDCPEVKRGVQYLVDTQRSDGSWEETCFTGTGFPKHFFIRYDNYRNC
FPLMALGQYLRKLEAKVSPPGRWVTEKK
>A0A534TEA3|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MDRSIEEARATERPFAARSAVRSRRDEFLAKVDHTINRSQEYFRREQHATGYWHRPLEAN
ATMDAEYIFFMHFMGRVNAERQERIAAHLLATQLEDGSWALYPDAPGHLSNTIEAYFALK
LAGRPASLPALEKARRFILERGGAAKAGVFTRIFLAYFGQFPWDGVPSMPAELILLPNWF
PINIYEMSSWARGTVVPLLALLAKRPFIRIPEDRGVAELFQRPPTPADYAFRRSAGAFSW
HNFFLVVDKTLKLLGRIPVAPLRTRALAAAGDWILAHQDVNGGWGGIQPAMVNSVMALRA
LGYPDDHPAVAKGIQAIEDFVIEEGRELFFQPCVSPTWDTALAAKALLDSGTPSDDPALQ
RAAEWLLENQIFRGGDWQVKNPDLEPGGWAFEFANDWYPDTDDTAVILMVLRRIAMTDER
HKAHAIQRGMNWTLGMQSRNGGWGAFDTDNLRELFNKIPFADMEAMLDQPTADLTGRHLE
LMGEYGYDLEMRRAKRALAFIRRTQEPDGSWWGRWGVNYIYGTWSVLSGLRAIGEDLRQP
YVRRAVAWLKSRQNDDGGWGETCDSYFDPSLAGRGPSTASQTAWALLGLLVGEDELSPEL
VRGIDYLTRGQQRDGTWDELHFTGTGFPRHFYLRYYMYRNYFPLMALGLFRARAETAASV
REAEASSA
>A0A524IB30|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MNPENPPPDGDRGAADPHPRFPSNRENPNNPPIPPERLHERISRAMDHLLSLQSAEGYWV
FDLEADVTIPSEYILLQRFLGRAIKPELGESIGRYIRRRQNPDGAWPLYADGFSDISTTV
KAYFALKLLGDPPDAPHMAKARQLVLSLGGASRVNVFTRIALALFGQIPWRTAPAMPVEI
MLLPKWFFFHLQKVSYWSRTVIVPLLILYARKPVCPLAVEEGVRELFLSPPDSFHDIDGF
VPGRVRKNLFVLLDRMLKRIERFLPTTKREKAIRLAERWIIERMQGEGGIGGIFPAMANA
VMALKILGYPDQHPDFVRGIKALDDLLRSRGDESFCQPCLSPVWDTCLCLSAVLEAGLSQ
EHPAVDDAVRWLLEQQIHARGDWADRAPTLEPGGFAFQFENAFYPDVDDTAKALIALFRS
GIFRKGRKTEQIAKAVNWVLGMQCVDGGWGAFDIDNHYLSLNDIPFADHGALLDPSTSDV
TGRSVEMLSMLGYRRDFPPIARAVKFLQREQETSGAWYGRWGVNYIYGTWSVLMALRQAG
EDMSQTYIRKAVDWLASRQNPDGGWGESCRTYHAPSLAGNGNSTSSQTAWALLALLAAGC
ENSPEVQRGIGYLLGTQNEKGGWDEALYTGTGFPRVFYLRYHGYSQYFPLWALGAYRRIR
EGGNTLQDEEKLAKPPNLPLPARK
>A0A7V7DNM0|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MRQNTRKAIKVVKKPKDSSDFSRQKEDAQPQGETSLFSIKRLNKVIKRSVDRFLSIQNAE
GYWVFDLEADTTIPSEYVLLQRFLGIQMAPDLKERIANYIRGRQLDNGGWPLFYDGDEDL
SGTVKAYFALKILGDAMDAPHMTRARNLILSLGGASRVNVFTRITMALFGQIPWRTAPAM
PIEIMLLPKWFFFHLHKISYWSRTVIVPLLILYARQPVCNLSPGETISELFQEPAENLRN
IDRYRSGDLAKSLLILLDRALKVVQPFMPKRPARKAVKIAERWTLKRMGEGGLGAIFPAM
ANAVMALKELGYPSDHPDFVRGLKSIEDLLVTHGSETFCQPCVSPIWDTCLSLSALREAG
IPADHEAVKDAVDWLFKKLITSRGDWAYRAHDLEPAGWAFQFENTYYPDVDDTPMVLMAL
QRAHAIDRVGYKNKMEKAVNWLVGMQSSDGGWGSFDIDNNYLYLNKIPFADHGALLDPST
SDLTGRCVELLSMLGYGLEFPPVSRAVEFLRKEQEECGAWFGRWGVNYVYGTWSVLKGLK
QAGEDMSKPYIRKAVEWLKSCQNPDNGWGESCNSYAGVSCAGKGKSTVSQTAWALLGLMA
AGEVKSSAVQRGVHYLLNAQDRQGSWEEKLYTGTGFPMVFYLRYHGYRQYFSLWALGEYR
RLRTGNKTSQDKAALNEPASFRLTALKKKR
>A0A7Z8R6Y9|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium sp. WL2|TrEMBL
MREAVSKVEPLQRSKTQGISLDDVERGVAQATRALINLAHDDGHICFELEADATIPSEYV
LFHHFRGTPVPEGLEAKIGNYLRRTQGRHGGWALVHEGPFDMSCTVKAYFALKMIGEDIE
APYMRRAREAILSRGGAANANVFTRFMLALYGEVPWRAVPVMPVEVMFLPKWFPFHLDKI
SYWARTTVVPLFVLQATKPRARNPRGISVQELFITPPESVRTWPGSPHATWPWTPIFGFI
DRMLQLVEDRLPRKSRQRAMEKARAWVSERLNGEDGLGAIFPAMVNSVLMYEVMGYRPDH
PQVRVACDAIEKLVVEKADEAYVQPCVSPVWDTALAAHALLEAGSPEAEAQARAGLDWLK
PRQVLDIVGDWAARKPKVRPGGWAFQYANAHYPDLDDTAVVVMAMDRAMHQHGLVAGMPD
YKASIARAREWVEGLQSEDGGWAAFDADNNHMYLNHIPFSDHGALLDPPTADVTARVVGM
LAQLGETRETSRALDRGVNYLLNDQEEDGSWYGRWGMNFIYGTWSVLCALNAAGVDSADP
RIQRSVSWLIRIQNPDGGWGEDASSYKIDPAFEAGSSTASQTAWALLALMAAGAVDDPAV
TRGINFLTRTQGADGFWNEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKRTNSRR
VQFGM
>A0A1A0D9C9|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter pasteurianus|TrEMBL
MNMASRFSLKKILRSGSDTQGTNVNTLIQSGTSDIVRQKPAPQVPADLSALKAMGNSLTH
TLSSACEWLMKQQKPDGHWVGSVGSNASMEAEWCLALWFLGLEDHPLRPRLGKALLEMQR
PDGSWGTYYGAGSGDINATVESYAALRSLGYAEDDPAVSKAAAWIISKGGLKNVRVFTRY
WLALIGEWPWEKTPNLPPEIIWFPDNFVFSIYNFAQWARATMMPLAILSARRPSRPLRPQ
DRLDALFPGGRANFDYELPTKEGRDVIADFFRLADKGLHWLQSSFLKRAPSREAAIKYVL
EWIIWHQDADGGWGGIQPPWVYGLMALHGEGYQFHHPVMAKALDALNDPGWRHDKGDASW
IQATNSPVWDTMLSLMALHDANAEERFTPEMDKALDWLLSRQIRVKGDWSVKLPNTEPGG
WAFEYANDRYPDTDDTAVALIAIASCRNRPEWQAKGVEEAIGRGVRWLVAMQSSCGGWGA
FDKDNNKSILAKIPFCDFGEALDPPSVDVTAHVLEAFGLLGLPRDLPCIQRGLAYIRKEQ
DPTGPWFGRWGVNYLYGTGAVLPALAALGEDMTQPYISKACDWLINCQQENGGWGESCAS
YMEVSSIGHGATTPSQTAWALMGLIAANRPQDYEAIAKGCRYLIDLQEEDGSWNEEEFTG
TGFPGYGVGQTIKLDDPAISKRLMQGAELSRAFMLRYDLYRQLFPIIALSRASRLIKLGN
>A0A7Z2GA84|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia acidiphila|TrEMBL
MNDLSQATPTEDLASRLTGADVADAPAVAMPAPAFAGETAAPVAAPLVPLASLDAAVARA
TDTILADQRADGHWVYELEADATIPAEYVLLVHYLGEEANLELEQKIARYLRRIQLPEGG
WPLFTDGAMDVSASVKAYFALKMIGDAEDAEHMVRAREAILAAGGAEQVNVFTRILLALF
GVVTWYAVPMMPVEITLLPQWFPFHLSKVSYWARTVIVPLLVLGAKRPVARNPRGVRIDE
LFRGAPVSVGLNARSPHQSKGWFGFFRAVDGVLRVTDPLFPTYLRQRAIDAAVAFVDERL
NGEDGLGAIFPAMANAVMMYDVLGYPADHPHRAIARQSLEKLVTVHTEEAYVQPCLSPVW
DTSLAAHALLETGDARAEEAARRGLEWLRPLQILDVRGDWISRREAVRPGGWAFQYANPH
YPDVDDTAVVVAAMDRVDKLDNTKTYDAPIARAREWVVGMQSSNGGWGAFEPENTQYYLN
NIPFSDHGALLDPPTADVSGRCLSMLAQLGELPAASEHALRAYNYLLDEQEADGSWYGRW
GMNYIYGTWTALCALNAAGLAHDDPRMQRAVQWLVQIQNDDGGWGEDGTSYKLEYRGYER
ATSTASQTAWALLGLMAAGAVDHPAVARGIDYLQKTQQEHGLWDETRFTATGFPRVFYLR
YHGYRKFFPLWALARYRNLKRAGVTRVTVGL
>A0A551ZWL8|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa Ma_AC_P_19900807_S299|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSDGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPANDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKIGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKAVDNFAIE
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKAVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNQYRHQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A6P0JJX1|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO4A5|TrEMBL
MQTQDRIVNSGVTEAIANSQSYLLAQQYPDGYWWAELESNVTITAEIILLHKIWGTDKER
PLHKAEAYLRSQQRKHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDSALVRARDFILR
RGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPQWFPFTIYEMSSWARGSTVPLLI
VFDQKPVFDIQPSITLDELYTEGADHAKFELPRNSDWTDLFVLLDDGFKLAEDLNLVPFR
KQGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPVVQRGLEAIDRFAIE
TPDSYRVQACVSPVWDTAWVLRAMVESGLEPDHPALVRGGEWLLQQQILDYGDWVVKNPQ
GKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLKQAAIARGLAWIASMQCNQGGW
AAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEMLGSCNLSIESQQLEKAIAFLIQ
EQEADGSWFGRWGVNYIYGTSSALSALSKIAPHTHQRSIERGAAWLVKCQNLNGGWGETC
LSYDDPSLKGLGISTASQTAWALIGLMAAGEATGNWARDAIEMGVNYLVSTQQPDGSWDE
TEFTGTGFPSHFYLKYHFYQQYFPLLALGRYQMSVSS
>H0T109|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. STM 3809|TrEMBL
MTVTSSASARAARDPGNYQTALQSTVRAASDWLIANQKPDGHWVGRAESNACMEAQWCLA
LWFMGLEDHPLRKRLGQSLLDSQRPDGAWQVYFNAPNGDINATVEAYAALRSLGYPDSEP
AVRRAREWIEAKGGLRNIRVFTRYWLALIGEWPWQKTPNIPPEVIWFPLWFPFSIYNFAQ
WARATLMPIAVLSAKRPSRPLPPENRLDALFPHGRHAFDYELPVKANAGGWDKFFRGADK
VLHALQNFGNKLNLGLFRPAATSRVLEWMIRHQDFDGAWGGIQPPWIYGLMALYAEGYPL
NHPVVAKGLDALNDPGWRVDVGEATYIQATNSPVWDTILTLLAFDDAGVLGDYPDAVDKA
VNWVLARQVRVPGDWSMKLPHVKPGGWAFEYANNYYPDTDDTAVALIALAPLRHDPKWKA
KGIDEAIQLGVDWLIGMQSQGGGWGAFDKDNNQQILTKIPFCDYGEALDPPSVDVTAHIV
EAFGKLGISRNHPSMVQALDYIRREQEPSGPWFGRWGVNYVYGTGAVLPALAAIGEDMTQ
PYIGRACDWLVAHQQSDGGWGESCASYMDISAVGRGTTTASQTAWALMALLAANRPQDKE
AIERGCLWLVERQSAGTWDEPEFTGTGFPGYGVGQTIKLTDPSLQERLMQGPELSRAFML
RYGMYRHYFPLMALGRALRPQGHGPSASTPTLSSRA
>T2AZI2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWAANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGSDNQAVARAIGYSKRGQEVNGSWFGRWG
>T2B030|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLAMHAVPVANSVPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDSPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWFGRWG
>T2AYM9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAAHAVLETLGGNTLLLNKSCDWLSKLQIKEHTGDWGWRRKGLRPGGWAFQYN
NKFYPDVDDTAVVGMALHRQNPEKYADTISRAEEWIIGMQSSNGGWAAFDADNEYYLLEN
LPFADHRALLDPPTADVTARCISFLTQIGTSNNHPISRGLEFLKRNQEEDGSWYGRWG
>T2AZ11|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTSIATIALREAGVSADDPAIRKSVSWLLSREVREPGDWSVRNKSCEPSGWFFEFN
NRYYPDVDDTSMVVMALRRSLPAMATEGWDADFLLDKWSPHAADKDAVAVLSVRINSPED
LRVGMESITPQLSAIWRGARWVLAMQNKDGGWGAFDANNTRVLYTQVPFADHNAMIDPSS
ADLASRMLEMFADLNVPCEHPALQRALKYIWDEQDPAHCWFGRWG
>T2AXY5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRANNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGSW
G
>T2AZN9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTAICSNALLDSGLPTDHPALVRAGKWIVSKQVTKRGDWQVKNPKAEPGGWAFEFY
NELYPDTDDTAEILLFLNRVEILDSRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGKWGFNKQHPQVKRAIKFVKERQEVDGCWFGR
WG
>T2AZ44|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAICSNALLDSGLPTDHPALVRAGKWIVSKQVTKRGDWQVKNPKAEPGGWAFEFY
NELYPDTDDTAEILLFLNRVEIPDNRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGKWGLNKQHPQVKRAIKFVKERQEIDGCWYGR
WG
>T2AY89|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLATHAMLEANLSSGPRILENDSASKACKWLENLQIKNCAGDWSVWRPNLRPGG
WAFQYHNDYYPDIDDTAVVAMALHRTGNKIYEPALLRAAEWIIGMQSKNGGWAAFDADNE
YHLLENMPFADHGALLDPPSVDVSARCISFLTQLGYDQTNGTIKHGIKYLKKNQEEDGSW
YG
>T2AYI2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGAPLDPPTADVSARCLSMMAQMGYGPDNPAVARAIRYLKRGQEANGSWYGSWG
>T2AYH2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLATHAMLEANLSSGPKILENDSTSKACKWLENLQIKDCAGDWAVWRPNLRPGG
WAFQYHNDYYPDIDDTAVVAMALHRIGNKIYEPALLRAAEWIIGMQPKNGGWAAFDADNE
YHLLENMPFADHGALLDPPSADVSARCISFLTQMGYDQTNGTIKRGIKYLKKNQEEDGSW
YGRWG
>T2AZP6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAAHAVLETHGGNTHLLNKSCDWLSKLQIKEHTGDWGWRRKGLRPGGWAFQYN
NKFYPDVDDTAVVGMALHRQDPEKYADTISRAEEWIIGMQSSNGGWAAFDADNECYILEN
LPFADHRTLLDPPTADVTARCISFLTQIGTSNNHPISRGLEFLKRNQEEDGSWYGRWG
>T2AZV2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLAVHAMLEAGEPKNGARLNKAMRWMADRQVCDVSGDWATHRPGLRPGGWAFQY
ANNHYPDVDDSAVVAMALDRASDPKVKQGLPRAVEWIVGMQSKNGGWGSFDAENSHYHLN
HIPFADHGALLDPPTEDVTARCVGMLAQIGDEAGNDAIERGLSYLRETQQPDGSWYGSWG
>T2AZT6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWASQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAITLLSLADKKIYEKNIKDGVDYIKSEQEEDGSW
>T2B072|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTALVSQALIEADKDQQTSAEIENALNWLKEQQLSDEPGDWRVQKPELTGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRVNNKKYVKPIQRAANWVAGMQSRGGGFGSFDINNTHFYS
NEIPFADHGALLDPPTADVTGRAIALLSLSDREKYAKNIKEGINYIKSEQENDDSWYGRW
G
>T2AZZ7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLATHAMLEANLSSGPRILENDSTSKACKWLENLQIKDCAGDWAVWRPNLRPGG
WAFQYRNDFYPDIDDTAVVAMALHRSENKIYEPTLLRAAEWIIGMQSKNGGWAAFDADNE
YYLLENMPFADHGALLDPPSADVSARCISFLTQMGYDQTNGTIKRGIEYLKKNQEEDGSW
FGSWG
>T2AY92|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDDPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNAHFYL
NEIPSADHGALLDPPTVDVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSW
>T2AZ66|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQPVSTEIETALNWLKEQQLSDEPGDWRIQKPELIGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPFADHGALLDPPTADVTGRAIVLLSLADKKIYTKNIKDGVDYIKSEQEENGSW
>T2AZD2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGFNGLSLLESGLTLKDSSTQKACKWLEKKQILEIKGDWIVNNKNLLPGGWAFQY
ENDFYPDVDDTAVIVMFLDRAGYQNKKRLEIACNWIIGMQSKNGGWGASDKDNTYHYLNN
IPFADHGALLDPPTADVSARCISMLSQINKKNYKKIIQKRVKFLKNEQENDGSWYGRWG
>T2B0G5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PVWDTCIAQLALLESGIDPGDPMVQSSARWLIDKQIYAAADWQVRAKGTRPGGWSFEFDN
LIYPDIDDASIVVMALDQVRLPEAEEPRRADSIQRGVEWMAGMQSKNGGWAAFDKDNNKK
YLTKIPFSDFGETLDPPSVDVTAHLLEMYGRLGYTKEDRAVGRGFAYVISEQEEDGSWFG
RWG
>T2AZM5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTCIAQLALLESGIDPEDPMVQSSARWLMDKQIYAAADWQVRAKGTRPGGWSFEFD
NLIYPDIDDASIVVMALDQVRLPEAEEPRRADSIQRGVEWMAGMQSKNGGRAAFDKDNNK
KYLTKIPFSDFGETLDPPSVDVTAHLLEMYGRLGYTKEDRAVGRGFAYVISEQEEDGSWF
GSWG
>A0A3P0NF05|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp9031|TrEMBL
MNDLTEMATLSAATAPAGLDAAVAGATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANSVMMYDVLGYAEDHPNRAI
ARKSVEKLLVVQEDEAYCQPCLSPVWDTSLAAHALLETGDARAEEAVLRGLEWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVAAMDRVQKLRQNDAYRDSIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGIEYLI
ANQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNATRVTVGL
>A0A3M2F941|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Hydrogenedentes bacterium|TrEMBL
MIVVNAGAIRRSSGEGSGEIDPAKAVERAVEVLLKLQSREGYWAGELFADATLAADTVIL
YSFLGMNPIPRSEEYRRHILSRQLSDGGWNIYPGGPAEINATLKAYTALKLIGLSKDEPC
LVKAREAIRGLGGLRGIHTYCRFYLAALGQIPWSKVPDIPPEIMLLPKSLPIGLHGLSSW
TRVIVVPMMIIRALEPVAKVPAERGVGELIEEFWAEKPPPRSRWGRFFLFLDGILRLYGK
IPFNPIRSVALKKAEEWMRRHLVEGGLGAIYPAIQNSIMALKTLGFDLDSPLLRDQLKEI
EGLHVFEGGEVRVQPCTSHVWDTAWSLTALAEAGFTLSHPALRRGVVWLLSKKLPAPTAR
NERGETMAAWSFEYQNPFFPDIDDTAAVLMALTLAGARTDAELGSRARAAIEEGTRWIRW
MRNRDGGWASFDKDVDCRILEHVPFADHNAILDPSTADITARVLECFSVTGVSITEEERR
GAVAFLLRNQEPNGSWFGRWGVNYIYGTSAVLVALSAYQGDSEVKRAVENGARWLKSVQN
EDGGWGESCSSYEEPGVYQAIESTPSQTAWAVIGLIAAGYGRGRAVKRGVGFLCRSQKSD
GTWDEHVFTGTGFPRVFYLGYSMYSHNFPIIALARYRRLNRIKTTVS
>A0A3S0H008|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobiaceae bacterium|TrEMBL
MTDIATMVAPERQHLDDGIASASRALLDVQKPDRHWVFELEADVTIPAEYILMRHYFAEP
VDTVLEGKIAKYLRRMQNDNGGWSLFYGHEFDMSASVKAYYALKMAGDSPDAPHMKKARE
TMLARGGAVKANVFTRIMLALFGQLEWKAVPVMPVEIMLLPRWFPFHLTKISYWARTVIV
PLLVLMTLKPRARNPLGIGVRELFIEDPKTIGPTPKAAHQSQVWFTSFDIIDRVLRLADP
FFPKAMRQRAIRKAEEFVTERLNGVDGLGAIFPAMVNSVMMYDVLGYPPDDPNRALARES
VERLLVIKDDEAYCQPCVSPVWDTALAAHAMIESGQAADLEAAKASLDWLLPRQVIDVKG
DWADKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRVRRMDGTTKYDDAIARAKEWIL
GLQSVDGGWAAFDADNLEYYLNNIPFADHGALLDPPTDDVTARCLSMLAQLGDTLETSEP
MRRAVAYLRKTQLADGSWFGRWGINYIYGTWSALCALNAAGVPHEDPMIAKAADWLEAIQ
NADGGWGEDGNSYRLDYKGYERYATTASQTAWATLALMAAGRVDRPATKNGIDNLMQSQG
ADGFWQEPDYTGGGFPRVFYLRYHGYSKFFPLWAMARYRNLRSSNSRFVGAGM
>A0A7V5FVH0|squalene-hopene cyclase|EC 5.4.99.17|Desulfobulbaceae bacterium|TrEMBL
LDPDAAPLKTAREWIVNNGGLAETRVFTRYWLALLGEWPWQYTPALPPEIIFIPPWAPFN
LYKFASWARATLLPLTILSARRPIRPLPPEKKLDELFPDGRTNFDFRLPRKKGVFSWERF
FLVTDYLLNRYVTFPVHPFRETAIRSCREWIIGHQDADGAWGGIQPPWIYSLMALGAEEY
ALDHPVMAAGLNGFNLHWSYERNGGIYLQPSESPIWDTVLSLLAFLDCGMPPGTLEAAEK
AVDYLLREQVLVGGDWQVFVKDAEPGGWAFEFENDKYPDVDDTAVAVIVLLRLLPLMKDT
ALQHRMQTAVDRAVAWMLAMQNPNGGWAAFDRDNTSKILTLIPFADFGELLDPPSVDVTA
HVVEALGLYGHNLESPAVARACRYMQREQEEDGSWFGRWGVNYIYGTAAVLPALEMVGEN
MQAEYIQRAARWLIEHQNKDGGWGESCGSYMDDDLRGRGPSTASQTGWALMALLAASSGD
FDQSIQQGLNFLCNSQRQDGTWDEPQYTGTGFPGYGVGERVNLAKDAGRFGQGRELARAF
MLNYNLYRHYFPLIAMGRAQNRLNQATTTAQHTNG
>Q07I43|squalene-hopene cyclase|EC 5.4.99.17|Rhodopseudomonas palustris (strain BisA53)|TrEMBL
MDSILAPRADAPRNIDGALRESVQQAADWLVANQKPDGHWVGRAETNATMEAQWCLALWF
LGLEDHPLRVRLGRALLDTQRPDGAWHVFYGAPNGDINATVEAYAALRSLGHRDDEEPLR
KARDWILSKGGLANIRVFTRYWLALIGEWPWEKTPNILPEVIWLPTWFPFSIYNFAQWAR
ATLMPIAVLSAHRPSRPLAPQDRLDALFPQGRDSFNYDLPARLGAGVWDVIFRKIDTILH
RLQDWGARRGPHGIMRRGAIDHVLQWIIRHQDYDGSWGGIQPPWIYGLMALHTEGYAMTH
PVMAKALDALNEPGWRIDIGDATFIQATNSPVWDTMLSLLAFDDAGLGERYPEQVERAVR
WVLKRQVLVPGDWSVKLPDVKPGGWAFEYANNFYPDTDDTSVALMALAPFRHDPKWQAEG
IEDAIQRGIDWLVAMQCKEGGWGAFDKDNDKKILAKIPFCDFGEALDPPSADVTAHIIEA
FAKVGLDRNHPSIVRALDYLKREQEPEGPWFGRWGVNYVYGTGAVLPALAAIGEDMRQPY
IARACDWLIARQQANGGWGESCVSYMDAKQAGEGTATASQTAWALMALIAADRPQDRDAI
ERGCLYLTETQRDGTWQEVHYTGTGFPGYGVGQTIKLNDPLLSKRLMQGPELSRSFMLRY
DLYRHYFPMMAIGRVLRQRGDRSGH
>K9XY11|squalene-hopene cyclase|EC 5.4.99.17|Stanieria cyanosphaera (strain ATCC 29371 / PCC 7437)|TrEMBL
MQTQDLVTQDQLQFAIAKSQDYLLSIQNPDGYWWAELESNVTITAEVILLHKIWGTDQTR
SQALQKAETYLRSQQREHGGWELYYGDGGELSTSVEAYMALRLLGVAAQDPALIKAKQFI
LQRGGISKTRIFTKLHLALIGCYDWRGLPSIPPWIMLLPEHFPFTIYEMSSWARGSTVPL
LIVFDRKPIFVTKITINLDELYAEGVNNCRYELPRNNDWTDVFLWLDDACKLAENFNLVP
FREEGLKAAEKWVLERQEATGDWGGIIPAMLNSLLALRTLDYEVDDPIIQRGLAAIDNFA
IETEDSYRVQPCVSPVWDTAWCLRALVESGLPPNHQTLVRGGQWLLDKQILDYGDWAVKN
KQGKPGGWAFEFDNRFYPDLDDSAVVVMGLAEVQLPNEAQKQSAIARGVNWMATMQCRAG
GWAAFDIDNDQDWINLIPYGDLKAMIDPNTADVTARVLEMLGQYHLAMKADQVNRAIAYL
ISEQENDGSWFGRWGVNYIYGTSGALSALAVIAPKDYQTEIDRGATWLVSCQNPDGGWGE
SCRSYHDQTLKGKGVSTASQTAWALIGLLAAYQATGFNAQSAIETGINYLLATQNNDGTW
YEAEFTGTGFPCHFYLKYHLYQQYFPLLALGRYQKLMK
>A0A7T0BZR1|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Nitrohelix vancouverensis|TrEMBL
MDSETIKRLETAIEKSRTFFLSQQYPEGYWVDELESNATITAEYIFFMHFMGRVDSVKME
KCANYLLKKQREDGSWPLFYGGACDINSTVESYLALKMAGIPVDRPEMLKAREAIFANGG
IAKTRVFTKIFLAMLGQSSWDFVPAVPVEIVLLPNCSPFNIYEMSSWSRGTVVPLSVVCA
YRPVFELPAEKGIAELFREEDRDLSIQPTGPAFSSWRNTFIYMDRFIKFLASFNVKPLRK
KALKAAERWILDHQEDEGDFAGIQPAMFNSMLALHYMGYPDDHPALVKGFEAIERFELSW
DDQLGFQACVSPLWDTAIGINALLDSGMSPDDPALVKGGEWILTKQVVKPGDWKVKNPDA
EPGGWAFEFYNECYPDNDDTAEILIALDRLDLPDHRHKLAECQRAMTWLLSMQSKNGGWG
AFDMDNDLQLLNEIPFADHKAMLDEPTADVTGRILWCLGRLGFSREHPQVRRALEFVRKM
QEPDGCWWGRWGVNYIYGTFLVTNGLRSMGEDMTQPYLRKTVDWLVAHQNEDGGWGETCD
SYADPSLRGQGESSCSQTAWAMLGLMALGEGQGEAMRKGAEFLMKRQLDETGSWYEPQFT
GTGFPVHFYIKYHMYQHFFPLMALSRYRNELTGVGNEEKR
>A0A7W7CED3|squalene-hopene cyclase|EC 5.4.99.17|Crossiella cryophila|TrEMBL
MPSFPHALTLSSALAGAVTHSLVHRRPDSSWCGTPDPRVLDTAVTAIALAACADEAGRAA
VARARSWLRHADPQTHHPLAYELEAALRALALGQEVRHTAASTDIVLSGRTRLLTVLAGH
SLPGAGCPRTALRAELDRGLRERLKPWTVVELLAGIAILAMRAGDLGEARAAVARLRPHQ
WPDGSFYGNPVCTALALLALALTGSEPDLLDRTRRRVLRTQQEDGTWRFCASEVWDTALM
VRAGQGLPRFDRHALPGALAFLAAAQNPDGGWSYTRGLESDNDTTGAVLLALGGRSLPGR
GLPRALAYLAGQQTADGLWRTWQYRQDPPAQDVVAHVLGGLHQYRGQHHIPLAPATRWLG
ECWQREGRWSSSWYRGLPYATAEVGAALAGQEVLDHAVKALLANQNGDGGWGAEAGLASS
AAATGLALLALSRSRVLDPDSREAAVTWLLRTRPADGTWAGEPDMYGPRPMLVHYPTQTH
AFVLLGLRAALVHRTSDVWCSDYRNGPAAGVPGSLLSRFST
>A0A7C5F3E7|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
MNIIKALFNRLSDSLLSTVQGRLDPATEFTPVASLRLVSDKPVVLPSLDSSTARRPIGHA
VSQPDAVDDAIRRSQSWFFNRQHAEGYWVAELEADTTLTSEYLMLRRFLDRVDPDREAKA
VRYLKTTQLPDGGWPIYYGGPAEISASVKAYFALKLSGVSADEPFMVRAKERILAMGGVL
QANVFTKITLALFDQYDWEGVPHMPVELMLLPKKFYFSIYAISYWSRAVLIPLLIVFAHR
PVCRIPCEQGIDELYPIPRAEVRYWKYPPFNKDQAWFTPHNFFVALDAMLKLYDRMPMRV
LREKALHKAATWMLDHLKGSGGLGAIYPAMANSIMALECLGYDTDDPLVVKALREIEELE
VYGSTIIDGEVVPTLHLQPCFSPIWDTALLANALIEAGVSQDHPALQKAGRYLMSRQTKT
VGDWIVSSPNAEPGGWYFQFENELYPDVDDSAVVIMALSKLKIAGQEDELNESIRRGMRW
VLAMQGSDGGWGAYDKDNNRVVFNYIPFADHKALLDPSTSDLAGRCLEMLGALGYDKAHP
AAVRALAFLKKEQEQDGSWYGRWGVNYIYGTWSVLAGLRAIGEDLSAPYIRRAVAWLESK
QNPDGGWGESCLSYRDDLDHHGKGESTPSQTAWALMALMAAGAIDSFSVARGVQFLLRRQ
MKDGSWEEVAHTGTGFPRVFYLRYHWYCQYFPFWALAMYRNLRSRGKMRADELRHHIQGT
DSYWPEH
>A0A538RSF8|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
MKLIRTLLGRLSDSLFVSVPEKLELATELSNVPPLRLVSDKSTLSAPVDAATRRPTSHLI
SQADALDDAVRRSQAWFLSRQHASEGYWVAELEADTTLTAEYLLLRRFLDRVDPKRECLA
VRYLRAMQLPDGGWPIFYGGPSEISASVKAYFALKLSGIAADEASMLRARDCILAMGGVV
CTNVFTKITLALFEQYDWKGIPSMPPEIMLLPRRFYFSIYAISYWSRAVLIPLLVVFANQ
PVCRIPQEQGIDELYVAPRSQIRYRNVPPFNKDQRWFTPHNFFVQLDRVLKLYDRMPLSW
LREKALQKAAIWMLEHLKGSGGLGAIYPAMANSIVALRCLGYQVDDPLVRKALHEIESLE
VHDTVSIGDQRVEVLHLQPCHSPIWDTALLMNALIETGMPQDHPSLQKGGAYLVSRQTKT
VGDWKFSSPAAEPGGWYFQFENEFYPDVDDSAVVLMALSKVRQRGTNWVLAMQGSDGGWG
AYDKDNNRIVFNYIPFADHHALLDPSTSDLTGRCLEMLAALGYDQTHPAVAPALRFLKRE
QETDGSWYGRWGVNYIYGTWSVLAGLRAIGVDLSEPYICRAVAWLESKQNPDGGWGETCH
SYGDDPAWSGKGESTPSQTAWAIMGLMSAGMTDAFSVARGVQYLLRHQIKDGSWEEVRHT
GTGFPRVFYLRYHWYCQYFPLWALAMYRNLRTRGKMRADELRPQILVSGCHRADR
>A0A522REE3|squalene-hopene cyclase|EC 5.4.99.17|Rhodanobacteraceae bacterium|TrEMBL
MPPDSGVPQQATAPRGKLGASGRLSAAIDAARARILAHQHADGYWQYELEADCTIPAEYI
LMLHYLGESDRLLEARLAEYLRNRQSHGGGWPLYPGGALDVSCSVKCYYALKLAGDHADA
AHMARARAAILSVGGAARSNVFTRIALALFGELPWRGVPFLPVEIVLLPRWFPFTLSKVS
YWSRTVMVPLSVLTSLKPRAANPRGVHVDELFVTPPEQERHYFHPRSLLNRALCVCDETL
RHLETLIPKRLRQRALKRAEAWILEHRNGDGGLGAIFPAMVNAYEALALMGYPAGHPACK
ETRKAIDDLLVVHDSEAWCQPCVSPVWDTGLACLALQKDADAPAARIEQALAWLVSRQLC
NAPGDWRDYRPNLSGGGWAFQFRNDAYPDLDDTAVVARALRQSPQAVKYAKAITCAADWL
VGMQSRNGGFAAFDADNDHKWLNQIPFADHGALLDPPTSDVSGRVLTLLSMLARERDRDA
RERVLRFLLDEQTPEGAWFGRWGTNYIYGTWSVLGALRAAGLSAEAPEIRRAAAWLKSVQ
QADGGWGEGNDSYLDPELRGRGARSGPAQTAWALLALMDAGEADNPAVARGIEYLLRTQK
DSAWHAARFNAPGFPRVFYLKYHGYNHYFPYWALVRYRNVQRHP
>A0A6J4FMH7|squalene-hopene cyclase|EC 5.4.99.17|Magnetospirillum sp. SS-4|TrEMBL
MSFSEKISLEKVISDSAAALMAKQRDDGHWVFQLEADATIPAEYVLYLHYLDERDPEMER
RIGVYLRDIQDRTHGGWPLFHGGDLNISASVKAYYALKAIGDDVDAPHMRTAREAILAHG
GAAASNVFTRTLLALFGQIPWRGVPIMPVEIMLLPKWFPFHLDKVSYWSRTVIVPLVVLM
SLRPRARNPLNVNIPELFVTPPETVTNWYLDEARSNWAYVFRALDRVLHKVFPFFPKGLR
RRAIDRAVAFVDERLNGIDGLGAIFPAMVNSVLMYDVLGVPKDDPRVVIAKQSIRNLIVE
EGERAWVQPCLSPIWDTALATHAMLEVGGPEAEAAARKACDWMVERQITDVVGDWAAQRP
GLEPGGWAFQYANPHYPDVDDTAVVMAALDRVDPQAYGESIRKGAVWLRGMQCKDGGWGA
FDAENTAYYLNHIPFADHGALLDPPTADVSARCVSVLSVLGKRHSDVTAHEGVDYLLREQ
EADGSWFGRWGTNYIYGTWSSLAALNAAGIAHDHPAMRKAVRWLESKQREDGGWGEDGRS
YWTDQPRGEATVSTPSQTAWALLGLMAAGEVANPAVARGVDYLMRTRNDEGLWDEAHYTA
VGFPRVFYLRYHGYRQFFPVWALARYRNLTTGNAGPVMHAL
>A0A537WEY6|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MTAVQELTALDRTLERGVERLLELQHPDGWWKGELESNVTMTAQHLFWHHVLGLRTPELD
RKIANELLARQRDDGTWAIWFEGPGDLDTTIEAYVALKLAGVDPGPLARDFIRRLGGIPR
ARIFTKCFLALLGQWPWQRIVPIPPELVLLPASAPLSVYDFACWARGTFVPLAVTAALRP
VRGSDVDLREIGARPGESRAAARPGGLRRRAIGVGERWVRARQEADGSWGGIQPPWVWAI
LMLASLGHGFEDATLRRAVEGWAGFTIDDGDRLRPEACQSPVWDTALAVLGLRAAGVTAD
HPQLRAAGRWLLEEEVTNPHGDWAIRVPELAPGGWAFEFENDLYPDVDDTVVVALALREL
GIGDAAARRGLEWTVGLQSHDGGWGAFDVDNDAMWLYKIPFCDFGKVTDEPTADVTAHAL
EALGPEEGYEGAVTRGLDWLLREQEDDGSWFGRWGVNHLYGTGAALPALEACGLPQDHPA
YRSAVGWLDSVQQPSGAFGEDVRSYAEPGWRGRGAPTASQTAWALLGYVAAGQSERLSTR
RAADYLSRIQRPDGDWDEQHFTGTGFPLDFMIRYHLYRLTFPLLALGRLRERLNA
>A0A832BDN6|squalene-hopene cyclase|EC 5.4.99.17|Chthonomonadetes bacterium|TrEMBL
SGGLGAIFPAMTHAVMAFKCLGYSDDSPEVQHELRELAAFEIEEGDEIRMQPCLSPVWDT
AITLNALMDSGLPPNHPAIVKGIQWLLSKQTTRKGDWAVKVKDTEPGGWYFEYENEYYPD
VDDTVMVLMALYKYACPNGEEWTSAPEPIREAMRRGLAWVFAMQNRNGGWASFDKDNDKM
ILQYVPYADHNAMLDPATEDITARTLEMASYYGYTRGDPRIRRAIEFLRQRQEEDGSWFG
RWGVNYLYGTWQVLRGLARIGEDIRSAMFQRATSWLKSVQNEDGGWGETCRSYDDPVAFK
AKGPSTASQTAWALMGLINAGDARSPEVQRGLAYLVRTQRADGSWDEPWFTGTGFPRVFY
LRYHLYCHYFPLWAMGQYAAATSDTASKSYDAPEHSNSE
>A0A7H1N0K5|squalene-hopene cyclase|EC 5.4.99.17|Defluviicoccus vanus|TrEMBL
MDGGKSMMSALALRIAPIRDELDVTIDEAASWLVQQQHDDGHWVFELEADATMASEFVLL
NHFLDEIEDPLEQRMGNYLRRIQGAHGGWPLFYDGDPDLSATVKAYYALKIIGDDPDAPH
MRKARELILNMGGAARANVFTRYWLALFGQVPWRAVPLIRPEAVLLPSWAPFHLDKVSYW
SRATMVPMFVVAALKPLARNPRGADVRELFVVPPEKQRKYLSNPTGHWLXAMFLAADHLG
RLAKPLYAPALEKAAIERAMEFIRERLNGEDGLGAIYPAMANTIMAMNVLDYPIDHPERQ
AVRRAINKLVVNRENEAYLQPCVSPVWDTSLAMHAIMETRGQGVGGPQAPAVKDGAGWLC
AHQVLDVKGDWTVNRPNVRPGGWAFQYHNAHYPDVDDTAVVVMALHRSDPDANAEAVARG
AEWVIGMQSSNGGWGAFDAENEHYALNHIPFADHGALLDPPTSDVTARCLGMLAQLGHGT
DHPAVARALDFLRGEQEADGSWFGRWGTNYIYGTWSVLCALNAVGEDMNSPYIRKAVTWL
KSRQRADGGWGEDCASYWAERXGLNAMASTPSQTAWALLALMAAGEVESPAVGRGVNYLI
TAPRDGGQWQEKHYNAVGFPRVFYLRYYGYSAYFPLWALARYRNLKRSNSKRPSVGI
>A0A2Z4MKV1|squalene-hopene cyclase|EC 5.4.99.17|Brevibacillus brevis|TrEMBL
MRIGTTRNPPMLFPLSSSGDVFYREVNELREVQQEINRIQAFLLQRQQEDGTWRFCLESS
PMTDSHMIILLRTLGIHDERLMEKLTAHITSLQHDNGAWKLYPDEHEGHLSTTIDSYYAL
LLSGKYTKDEPRMALARSFILEKGGLTQANMLTKFSTALTGQYQWPPHFLVPVEIALLPP
SFPVSFYDFVGYARVHLAPMMIVADRKYVKKPDDAPDLSDLYADTPITRGLYPHRFLENF
LQEGQAFLATIHDSLQRLPFLPGQLHKLALRRLEQYILARIEPDGTLYNYSTSTLFMIFA
LLARGYSPKDPLIQKAMQGLTNSVYDYENGAHLQLATSAVWDTALLASSLQKSGLSTTHP
AIQKANRYLLQKQQHTYGDWKIRNPNGKPGGWGFSDYNTMNPDIDDTTAALRSLRHLART
DITTAAAWNRGLEWLLSMQNDDGGWPAFERNTDADFIRHLPIEGADTVSTDPSSADLTGR
TLEFFGNYADRTLTDPHVEKGVRWLLKHQESDGSWYGRWGIAYLYGTWAAITGLMAIGFS
PTDPAIQKAVAWLVANQNPDGGWGESCQSDQKKTYVPLGASTPSQTAWATDALIAVSSNP
TPELQRGIRYLLTHNQANDWTTRYPTGGGRPGGTYFAYHSYRWIWPLLALSHYQTKYANT
>A0A4V3M3W6|squalene-hopene cyclase|EC 5.4.99.17|bacterium M00.F.Ca.ET.191.01.1.1|TrEMBL
MNDLSQAHVLAAAGPENAGETGSAPATASTATATAPGSATATATAASAGFAPALDAAIAR
ATDAILAAQHADGHWVYELEADATIPAEYVLLVHYLGETPNLELEQKIARYLRRIQLPDG
GWPLFTDGALDVSASVKAYFALKMIGDSADAEHMVRAREAILAHGGAEAVNVFTRILLAL
FGVVSWRAVPMMPVEITLLPMWFPFHLSKVSYWARTVIVPLLVLNAKRPLARNPRRVRID
ELFRGAPVNTGMPARAPHQHVGWFRFFRVVDTVLRAVDGLFPKATRERAVRQAVAFVDER
LNGEDGLGAIFPAMANSVMMYDVLGYPADHPNRAIARRSIEKLLVIKDDEAYCQPCLSPV
WDTSLAAHALLETGEPRAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYNNA
YYPDVDDTAVVAMAMHRSGALTQSDVDREAIARAREWVVGMQSSDGGWGAFEPENTQYYL
NNIPFSDHGALLDPPTADVSGRCLSMLAQLGELPQNSEPAQRALDYMLKEQEPDGSWYGR
WGLNYIYGTWTALCSLNAAGMPHDDPRIRRAAQWLLSIQNEDGGWGEGGESYKLDYHGYE
RAPSTASQTAWALLGLMAAGEVDNEAVARGIDYLQREQREHGLWDETRFTATGFPRVFYL
RYHGYRKFFPLWALARFRHLKRNGLTRVAVGM
>A0A0P8BXP9|squalene-hopene cyclase|EC 5.4.99.17|Phormidium sp. OSCR|TrEMBL
MDTNTLQQSIRATQTYLLNQQHSQGYWWANLESNVTMLAEVILLHKIWGVEDRFPWRKAE
QFLRDEQREHGGWELFRGDGGELSTSVEAYLGLRLLGVPPDDPALVTAKQFILAKGGISK
TRIFTKMHLALMGAYDWRGIPSIPAWIMLLPGEAPFSIYEMSSWARGSTVPLLIVFDQKP
VYRLNPSVSLDELYAEGVHAARFELPRQGDWSDGFVELDNLFKLGETLNLVPFREQGLKA
AEQWVIERQEASGDWGGIIPAMLNSMLALRSLNYDLADPVVQRGFEAIARFGVETDQHYW
VQPCVSPVWDTAWVLRSLVESGLDPDDARIVKGATWLLEQQILDYGDWSVKNPTAEPGGW
AFEFDNRFYPDLDDSAVVVMALNQSQLPNEAQKQAALTRGIRWMLSMQCSNGGWAAFDID
NDQDWLNALPYSDLKATIDPPTADVTARLLEMAAELDPEGTDGPLQEYSQQFERALAYLL
GEQEPDGSWFGRWGVNYIYGTSGALSALALITPQRHRSALERGANWLLAVQNADGGWGET
CLSYDHPRFKGNGDSTASQTAWALLGLMAVVKGLQVDSSHPWRESIQRGVAYLIETQQPD
GTWQESWFTGTGFPSHFYLRYDYYRLYFPLLALGRFAAEGTLHD
>A0A6G8U8X7|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. 1(2017)|TrEMBL
MDSVNATSRETLESKTLESSIASATQGVLEFQQSDGHWVFELEADCTIPAEYILLRHYLA
EPVDTALEAKIANYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDSVDAPHMVRA
REAIHARGGAINSNVFTRFLLATFGVVTWRAVPVLPIEIVLLPFWSPFHLNKISYWARTT
MVPLMVIAALKPRARNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFVLFRSLDAILRVI
EPMFPKSLRKRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKDENYPPRATTR
RGIDKLLVIHGEEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLDWLIPKQELEV
KGDWAVKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGVAGYDAAIARGREW
IEGMQSRDGGWAAFDVDNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETEKTS
KHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDHKDPMIRKAAGWLAS
IQNEDGGWGEDAVSYRLDYKGWEAAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIAT
QNKKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A1L7F6V6|squalene-hopene cyclase|EC 5.4.99.17|Actinoalloteichus sp. GBA129-24|TrEMBL
MTKVDDALAQAVDWLLKQQDSEGYWYAPVLTNVTAEAGELFMHEFLGTRTEEYTTTTARW
IRSQQRADGTWATFPGGPAELSVTIEAYLALRLAGDRPDEPHMAAAAAFCREAGGAERSR
MVTRIWLAILGQWSWDELPVIPPELMFVPRESSMSVYGFSGWTRMAVIPLTLISSHRPTV
TLPFDVDELRSEQPVPPPADPPLLSWPGMFVRMDRLLHRYERRPVARVRRTAARLAEQWM
MRHQEVDGSWLGIHLITVFGLLGLGAAGYRADHPTMVAGLRGLSRFAVTEQTPQGVARRV
ACCPGPVWDTALVVLALLDSGTDPADDRVRAAAEWLLDREIRTKGDWAVNRPDLVPGAWS
FPFAMEHFPDCDDTSLVVLALHRVAEADGSPIAERAAAAADRGFGWLFGQQSENGGWAVY
DADKTSDILAQLPFCDFGVATDPPSVDITAHVVEAFARILPPDDPRMRNGALYLLKTQEE
DGSWFGRWGANYVYGTGAAVPALIAAGASPQSRAVRRAVRWLVDHQNADGGWGEDLRSYD
DDSWRGRGESTPSQTAWALLALHAAGEGEDTDVVRRGIEWLTSRQLPDGTWEEHLFTGTG
FPGDFYIGYPLYRQIFPIMALGRYRRQPVTGSPASVAAESSKTISR
>A0LJS0|squalene-hopene cyclase|EC 5.4.99.17|Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)|TrEMBL
MRRLDTFPPEIPTGSRDKPPSGEEHSCSTPAEPLRSRLDEGILRAVDWLVCDQHPDGFWA
GMLQSNSCMEAEWVLAMHFLGIDDDPKYDGVIRAILGEQRADGSWGVFHKAPNGDINTTV
ECYAALRASGLAPESAPLSSAREWILAGGGLANIRNFTKYWLALIGEWPWEGTPTIPPEL
IFFPPRMPLNIYHFASWARSTIVPLSILSARRPVRPLPEDRRLDELFPQGRSAFDFRLPR
KDGWLSWEGFFHVCDRILRLYARTRRAPFRETAIRVCLEWIIRRQETDGAWSGIQPPWIY
ALLALHAEGYGLDHPILRAGLRAFDSHWSYERDGGIYLQASESPVWDTVLSLRALADCGE
ERKASVSIASALEWLLNRQISVPGDWAVRVPSVPCGGWAFQRANSFYPDVDDTAVAIEVL
ARLRPFTANQSAVDRAIRSARDWVLAMQCSNGGWAAFDRDNDFKLVTKIPFCDFGELLDP
PSVDVTAHVIEALAALGWDMTSREIEAAVSFIRREQEAEGSWFGRWGVNHIYGTATVLPA
LRAIGEDMSSAYVLRAADWLASRQNADGGWGETPASYMDDSLRGVGESTASQTAWAIMGL
VAVGSGAHDDTVRRGIDFLLFAQHGGTWEEPQYTGTGFPGYSVGERIRLRDMGASLKQGT
ELQRAFMINYNLYRHYFPLMALGRARYHLQLRRSAREGGNGETTPNGSAL
>A0A522VT65|squalene-hopene cyclase|EC 5.4.99.17|Methylococcaceae bacterium|TrEMBL
MDHLNLQAATLGAQASDLDLAIDHARNYLLSRQHAEGYWVFELEADCTIPSEYIMMMHFM
DEIDAELQRKIANFVRGRQNADGSWPLFTGAPGDISCTVKAYYALKMAGDDVDAPHMALA
RAWVLSVGGAAKANVFTRIALAMFEQIPWRGTPFIPVEIMHLPRWFPFHLDKVSYWSRTV
MVPLFILCSLKVKARNPQQIHIRELFVTPPEQERGYFDYVKTPLGKAILAVERTARLFEP
LFTKKMRESAIQKAFAWFEPRLNGEDGLGAIFPAMVNAYEAMDAIGIPADDPRRVTAKRA
IEKLLVIQDENTVYCQPCVSPIWDTALTALAMQEVIACDDHATTKTAITHSLQWLADQQI
AADAPGDWRVQCKEGEVCGGWAFQFGNSYYPDVDDSAVVAVALQQAGDPQFADTLERAGS
WIAAMQSSNGGFGAFDVDNTHYYLNHIPFADHGALLDPPTADVSGRCAMFLAMLVDKQPH
LQPALDRALDYLHDEQEDDGAWFGRWGTNYIYGTWSVMLAYEYAGLPKDDPRITKAVAWL
KSVQRHDGGWGESNWTYHDAATRGQFEYSTAFQTAFALIALIAAGEADCAEVRAGVEYLL
RTQQADGVWNDPCFTAPGFPKVFYLKYHGYDKFFPLWALAKYRKAVSAHRAA
>A0A7G8Q320|squalene-hopene cyclase|EC 5.4.99.17|Dyella telluris|TrEMBL
MTDTAATLTPAALPPTRPVQPESDRIEQAIERARRALMARQKPDGHWSFEFETDCTISSE
YILMMHFIDEIDDVLQEKLARYIRLKQRLDTHGGWPLYHDGALDVSCTVKSYYALKAAGD
SPDAPHMRRAREALLSRGGAAKSNVFTRILLAMFGQVPWRAAPYVPVEIMLFPRWAPFHL
DKVSYWARSTMVPLFILCSMKAKAKNPRKVGVPELFVTPPDQERHYFTTTTFVSRLFLVL
DKLGRAVDPLIPTALRRKAIQRAEAWFLPRMNGEDGLGAIFPPMENALEAMDLLGYAKDH
PARATCLKSLQKLIVHRDDGTAFCQPCVSPVWDTGWAAMALLRASPDDATQQSVARAMEW
LAPLQELELKGDWAVQAPDLAPGGWAFQYANAYYPDLDDTAVVAGLLHVAVRGTPQEGRY
RERIERAADWLVGMQSDNGGFAAFDRNNTHYHINDIPFADHGAMLDPPTEDVSGRVLAFL
GVIARPQDQPAIARCVDYLRAAQRPDGSYWGRWGTNYIYGTWSVLAGLALIGEDMRQPWI
RKSVDWLAGKQHGDGGWGETNDSYYDAGLRGTNGGVSTPHSTAWALLGLLAAGEHDSEAV
RRGIRWLLDHQQSQGEPEADLWYHPSFNAPGFPRVFFLKYHGYTAYFPLWALTRYRQLLA
RTRSNP
>A0A5B8Z4L6|squalene-hopene cyclase|EC 5.4.99.17|Bacillus dafuensis|TrEMBL
MSVVKNDISEGIDEIIDLLKKDQTPNGAWTYPFETGISTDSYMIILLRSLEINDEKLIYQ
LTERILSKQEKDGAWKLFHDGEGNISITLEAYYALLYSGYYQKNDERLRAARQFILNKGG
IEKSHMFTKIMLAITGQIKWPPFFPIPLELILLPLSFPINFYSFPEYGRVNMAPIMLLAD
RKFRLKTKNSPNLSELKVREDSEFDRESVEWRSLYSSIKNGIDRLMGLPSHIHKLATDQT
KHYMLTRIEKDGTLYGYFSSTFLMIFALLSLGYSKTHPIIINAVKGLMDMKCEINGLPHM
QYTTATVWNTSLINYALQEAGLPPSDPMVKKANQYLLKRQHYKYGDWIIHNPKAFPGGWG
FADINTLHPDVDDTTASLRSIARSVQHAPSFFQSWERGVQWVLSMQNKDGGWPAFEKDTD
SKWIKLIPIEKANYILSDPSTADLTGRTLEFLGNYTNLLKEHPSIKLAVHWLMKDQKNDG
SWYGRWGNCYIYGTWAAITGLMATGLLPAHHTISKAVKWMKEIQNHDGGWGESCKSDEKG
KYIPLNTSTLTDTAWAVDTLISVSDQPTKEINSGIKFILNNINIEDWTSEYPKGQGMAGD
FYIHYHSYRYIFPLLTLAHYKNTYLVE
>A0A844A5G9|squalene-hopene cyclase|EC 5.4.99.17|Rhizobium fredii|TrEMBL
MNKHSGNRTAIDPAALEMSIASATEALLAYRHADGHWVFELEADSTIPSEYILLRHYLAE
PIDVVLEAKIGNYLRRTQGAHGGWPLVHDGPFDMSASVKSYFALKMIGDSVDAAHMVKAR
EAIRARGGAANSNVLTRFLLALYGVVSWRAVPVLPIEIVLLPIWSPFHLYKISYWARTTI
VPLMVLAVLKPRAKNPKGVGIEELFLQDTKSVGMNPKAPHQSWGWFLLFRGIDGILRVIE
PHLPKKLRERAIASALAFTEERLNGEDGMGAIYPSMANIVMMYDALGKDDHFPPRAIARR
AIDKLLVIGEEEAYCQPCLSPVWDTALTCHALQEVGGANALAKAKQGLDWLKPRQVLDVK
GDWAVKAPNIRPGGWPFQYNNAHYPDLDDTAVVVMAMDRAQRHAGSKEYATAIARGREWI
EGMQSRDGGWAAFDVNNLEYYLNNLPFADHGALLDPPTEDVTARCVSMLAQVGEFTQSSK
AVAEGIAYLRRTQHAEGSWYGRWGLNYIYGTWSVLCALNAAGIDHQDPMIRKAVEWLVSI
QSWDGGWGEDAISYRLDYSGYEQAPSTSSQTAWALLGLMAAGEVEHPAVARGVNYLKNAQ
TENGLWDEQRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNV
>A0A7T2U630|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia humptydooensis|TrEMBL
MNDMTEMHTLDATAVPAAPAAADAPAPSAATTGLDAAVARATDALLAAQNADGHWVYELE
ADSTIPAEYVLLVHYLGEEPNAELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYF
ALKVIGDDENAEHMQRARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIILLP
QWFPFHLSKVSYWARTVIVPLLVLNAKRPVAKNPRGVRIDELFKSAPVNTGLLPKQPHQH
AGWFAFFRAVDGVLRLADGLFPRYTRERAIRQAAAFVDERLNGEDGLGAIYPAMANAVMM
YAALGYPEDHPNRAIARQSIEKLLVVGEEEAYCQPCLSPVWDTSLAAHALLETGDERARE
AAVRGLDWLVPRQILDVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVVMAMDRVAK
HDQTDAYRESIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVS
GRCLSMLAQLGETSASSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAG
LGHDDPRVKRAAQWLLSIQNPDGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAG
EVDNPAVARGIGHLLGTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNL
KRAGAARVTVGM
>A0A6I4MC09|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura physcomitrii|TrEMBL
MTATEPTETTATEPTATAASAGAARTPAEAMAAARDHLLGLQAPEGWWKGELQTNVTMDA
EDLLLREFLGIRTADDTREAARWIRSQQAPDGTWANFHDGPPDLSTTVEAYVALRLAGDE
PDAPHMRRAAAFIRGEGGIPATRVFTRFWLAMFGHWPWDELPVVPPEMVFLPRWFPLNVY
DFACWARQTIVPLTVVAAKRPVRPLPFALEELRSGRPVRRGRRGRWGLPGWDEAFGALDR
ALRVYERRPLPGLRKAALRRAGEWIIARQEPDGSWGGIQPPWVYSLLALHLLGHGLDHPV
VRRGLEGLERFTIRDAKGRRLEACQSPVWDTVLAMNALVDAGVPADHPALEAATEWVLGE
EVRGPGDWSVRRPDLPPGGWAFEFDNDYYPDTDDTAEAVLALGRVGRPEAEPAIERGVRW
MAGMVSRDGGFGAFDADNTRALCRRLPFCDFGEVIDPPSADVTAHVVEALSLRGMADSTL
VKRAVVWLLRAQEDDGSWFGRWGANHVYGTGSVVPALVAAGVRPEKPVIRRAVRWLERYQ
REDGGWGEDLRSYRDPEWVGHGVSTASQTAWALLALLAAGERGRAVERGVRWLVERQRPD
GTWDEEHFTGTGFPGDFYINYHLYRLVFPLSALGRYVKEIGS
>A0A7C2HCE8|squalene-hopene cyclase|EC 5.4.99.17|Bryobacterales bacterium|TrEMBL
MDSVWFENVNRRVTRRTVSVAAATRQSLAQACKQSLERAGEALLDLQKPEGYWCGDLLAD
TTLESDYILLQLWLYPPDATGWHPPTLERVRKAARSILRRQLPDGGFDIYPGGPADPSAS
VKAYAALKLAGIDPESAEMQRLRDCILRLGGMQAANSYTKINLSLFGLYPREHVPTIPPE
LVLLPGGVLYEMSSWTRAIVVPLSIVQSRGGTRPVPPGFHLNEIIAPGKSFRLPRRDKLS
FLFLGIDRGLKIWQDRGNARVKNAAIRAAEKWLIDHTRWSEGLGAIYPSMMYLIMALDAL
GYPRDHPDLVDAIRQFDALLTERGDEFYFQPCFSPVWDTAYAAFALGEMGQAPPERLRLA
ADWLIAREVRHKGDWSVKRPDLEPSGWAFEFANEHYPDIDDTAMVLLALLHAKASDPEAQ
ARCERRAVNWLLGMQSKDGGWAAFDVDNDWQLLNKVPFADHNAMLDPTCPDITGRVLESL
CRRGLVHSHPAIRRGVEYLLSTQERNGSWYGRWGVDYIYGAFLAMRGLRYSGAPGVLEAV
RKAARWLAAVQNPDGGWGESCASYAVDHFVPGPSTPSQTAWALLGLLAAGESYYDGVRRG
IEYLIETQQADGTWKEDLATGTGFPNVFYLRYTLYSKYFPILALTMARRALGQNEAAVLH
AAGGLAS
>A0A7X2PUR9|squalene-hopene cyclase|EC 5.4.99.17|Bryobacterales bacterium|TrEMBL
MSPSLQVTDTLLTGCSRTLRQAVSFLLGKQHRDGYWWADLTADTTLESDFIVLELWRHPP
VNGVWNPPSRERIQKAVRSILARQLPDGGFNIYAQGPSEISACVKAYTALKLAGLAYDDP
SLARLRERILALGGLQAANSYVKVNLSLFGLYPREHAPSIPVEGMLLGRLIYEMSSWTRA
IVIPLAIVDALNTGRPAPAGFTVDELRAPGVPLSFPNDEGFFSWRNFFLLADRTLKFWER
HGSKALRRLAIRRAEKWMLERTRYSDGVAAIYPPMMYVIMALDLLGYSKGHPHVVEAEQQ
FFNLLVDDERGFFFQPCFSVVWDTGIAAYALGESGQAPDHALARSTDWLLTKEIRRRGDW
SVKRPNVEPSGWYFELANEFYPDIDDTAQVLLALARSRGSDPVKQDACMRRAVDWLLAMQ
SKDGGWAAFDVDNNWEFLSSVPFADHNAMLDPTCPDITGRVLEGLSACGVKRDHSAIRRG
VEFLKRTQEQDGSWYGRWGVDYVYGTFLALRGLEAAGENNREAYILRAGEWLRSIQNGDG
GWGESCESYDRGTFVAAASTPSQTAWAVLGLLASGDSTSDSVHKGVEYLMETQRADGGWD
EALATGTGFPRVFYLQYHYYRHSFPVLALACYLKAKGAPGADRK
>A0A558AEP6|squalene-hopene cyclase|EC 5.4.99.17|Amycolatopsis rhizosphaerae|TrEMBL
MTSTTEPVHRPEPLAAEAGAALGRAVAHLKAAQEPGAWWKGELETNVTMDAEDLLLREFL
GIRTAQETEEAARWIRSQQRPDGTWANFYGGPGDVSTTVEAWVALRLAGDAPEEPHMAAA
AKFVLAQGGVERSRVFTRIWLALFGLWSWDELPNMPPELIFLPSWFPLNVYDWACWARQT
VVPLTVVATLRPVRPLPFGIDELRTGRRLRAKARPWTWPGAFHYLDKALHTYAKLPVKPL
RGLAMRQAAEWILARQEADGSWGGIQPPWVYSLLALHLLGYPFEHPAMRAGLTGLDGFVI
REHTGQGWVRRLEACQSPVWDTGLALTALADAGVPADDPAVLKAADWLLGEEIRQRGDWS
VRRPATPPGGWAFEFANDIYPDTDDTAEVVLALRRTAHPDQPRLKDAIERAITWLLGMQS
ADGGWGAFDADNTRTVTTQLPFCDFGAVIDPPSADVTAHVVEMLAAEGLAGTTECRRGVA
WLFGAQEEDGSWFGRWGANHVYGTGAVVPALVAAGVPAGVPAIRRAVAWLAAHQNPDGGW
GEDLRSYRDRSWIGKGTSTASQTAWALLALLAAGERESSTVERGVRWLLETQRPEGGWDE
PQFTGTGFPGDFYINYHLYRLVFPISALGRYVGAR
>A0A6N8VS26|squalene-hopene cyclase|EC 5.4.99.17|Holophagales bacterium|TrEMBL
MASLTRGLHERPESSPTPPPRVIDLMIDAAIRNLLGQRRDDGHWCAELEGDTILESEYVL
LLHFLGRGDDPRVAACCERLRGQQQQGGGWAIYPDGPTDPSVSVKAYLCLKLAGDDPQSP
RMADARRAILRAGGLGACNSYTRLYLSIFGLWTWRRSPAVPPELILLPRWFYFNLHEMSS
WTRTIVVPLSVIWALKPSVPLAVTLDELQVDSPPRRRGTTLYESFWSRVFAGVNGLIKLV
EVIGPVPGWRRPALKKAEEWLVAHVEGSDGLGAIFPAMVNAVIAFRCLGYEESHPLVQGQ
LRELERFEIEEAGEMRLQPCLSPVWDTALSVGALLAADMDGNDAPIREAVEWLLEREVTV
AGDWREKSLQDASGGWCFEYRNDHYPDCDDTAEVLLVLAAVRGRAGELEARKQAAAARGK
RWLLGLQNPDGGWASFDRCCDKEVLTLIPFADHNAMIDPSTPDITARVISALLAHGHDST
DGPVRRATDYLLREQEKDGSWPGRWGANGIYGTWLALSALAPLAARPGGRAGERLSRACR
LGRRWLLAVQNEDGGWGESLRSYDDPAFRGRGRSTASQTAWAMMGLMASLESRPWSDDAA
RTVTALDRAVAFLQERQRDDGSWYDRDWTGVGFPGVFYLRYHGYAQYFPLEALAAYRRLA
VPEPDAMPATGPF
>A0A6J7ZSV0|squalene-hopene cyclase|EC 5.4.99.17|Planktothrix rubescens NIVA-CYA 18|TrEMBL
MISSKTIAGVKQITMEIENQVSVNQLKDAIAASQNFLFSQQYPEGYWWAELQSNVTIISE
VILLHKIWGTDKTRPLYKAETYLRSQQRDHGGWELFYGDGGELSTTVEAYMALKILGVSE
TDSALIKAKQFILEQGGITKTRIFTKLHLALIGCYDWRGIPSIPPWIMLLPEGSPFTIYE
MSSWARSSTVPLLIVFDKKPVFRFNSSLNLDELYVEGRENAIFELPKNNDWTDIFLGLDQ
IFKFAELFNVVPLREQGLKAAEKWILERQEITGDWAGIIPAMLNSLLALKCLNYPVSDPI
VQRGLEAIDNFAIETEESYRMQACVSPVWDTAWVVRALIESGIDPNNADIVKSSKWLIRQ
QILDYGDWNIKNKQGKPGGWAFEFANKFYPDLDDSAVVVMALNQAKITDEPLKTATIIRG
IDWMISMQCKAGGWAAFDIDNDQDWINAVPYGDLKAMIDPNTADVTARVIEMLGELDPNS
SEFQLKIQSLKPSIERAISYLKQEQETDGSWFGRWGVNYIYGTSGVLSALAVINPIYKNW
GYTSLNPLMERGTNWLVSCQNIDGGWGETCHSYNDTKLKGKGVSTASQTAWALIGLMATG
CYEMEVIQRGINYLISIQLSDGRWDESEFTGTGFPGHFYIKYHYYQHYFPLLALGRYQKL
QQL
>A0A552FAY5|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa Ma_QC_Ca_00000000_S207|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSDGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDLALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKAVDNFAIE
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKGVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVKMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRHQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLITQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A4R4UPQ7|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. 7K507|TrEMBL
MTAVETGTVSRTAAEALEAAREHLLLLQSPEGWWKGELQTNVTMDAEDLLLREFLGIRDS
GDTGGDTGETARWIRSRQAPDGTWATFHDGPPDLSTTVEAYVALRLAGDRPDAGHMIRAA
AYIRSEGGIPATRVFTRFWLAMFGEWSWADLPVLPPEMMFLPRWFPLNVYDWACWARQTI
VPLAVVGAFRPVRPLPFGLDELTPDYHVPRRREPGLPGWDEAFKGLDKALHVYERRPVKP
LRRAALRRAADWIIARQERDGSWGGIQPPWVYSLLALHLMGYGLDHPVMRRGLEGLERFT
IRDEKGRRLEACQSPVWDTVLAMNALADAGLPAGHPALERAADWVIGEEVKGPGDWSVRR
PDLPPGGWAFEFDNDCYPDTDDTAEAVIALNRVRHPEAEPAIERGVRWMAGMASGDGGFG
AFDADNTRALCRKLPFCDFGEVIDPPSADVTAHVVEAMSHRGMADSLTVKRAVVWLLKAQ
EADGSWFGRWGANHVYGTGAVVPALIAAGVRPGKPAIRDAVGWLERHQRDDGGWGEDLRS
YRDRSWIGHGLSTPSQTAWALMALLAAGERGRAVERGIRWLAEHQRPDGTWDEDHFTGTG
FPGDFYINYHLYRLVFPLSALGRYLEGA
>S6D3E5|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter pasteurianus 386B|TrEMBL
MNMASRFSLKKILRSSSDTQGTNVNTLIQSGTSDIVRQKPAPQVPADLSALKAMGNSLTH
TLSSACEWLMKQQKPDGHWVGSVGSNASMEAEWCLALWFLGLEDHPLRPRLGKALLEMQR
PDGSWGTYYGAGSGDINATVESYAALRSLGYAEDDPAVSKAAAWIISKGGLKNVRVFTRY
WLALIGEWPWEKTPNLPPEIIWFPDNFVFSIYNFAQWARATMMPLAILSARRPSRPLRPQ
DRLDALFPGGRANFDYELPTKEGRDVIADFFRLADKGLHWLQSSFLKRAPSREAAIKYVL
EWIIWHQDADGGWGGIQPPWVYGLMALHGEGYQFHHPVMAKALDALNDPGWRHDKGDASW
IQATNSPVWDTMLSLMALHDANAEERFTPEMDKALDWLLSRQVRVKGDWSVKLPNTEPGG
WAFEYANDRYPDTDDTAVALIAIASCRNRPEWQAKGVEEAIGRGVRWLVAMQSSCGGWGA
FDKDNNKSILAKIPFCDFGEALDPPSVDVTAHVLEAFGLLGLPRDLPCIQRGLAYIRKEQ
DPTGPWFGRWGVNYLYGTGAVLPALAALGEDMTQPYISKACDWLINCQQENGGWGESCAS
YMEVSSIGHGATTPSQTAWALMGLIAANRPQDYEAIAKGCRYLIDLQEEDGSWNEEEFTG
TGFPGYGVGQTIKLDDPAISKRLMQGAELSRAFMLRYDLYRQLFPIIALSRASRLIKLGN
>A0A552CGH2|squalene-hopene cyclase|EC 5.4.99.17|Microcystis sp. Msp_OC_L_20101000_S702|TrEMBL
MQIQDKITEIAAKTAKAIKLSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
KRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPANDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVDDPIVARGLKALDNFAIE
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKAVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVKMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRHQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYQALI
>A0A7C3KBD8|squalene-hopene cyclase|EC 5.4.99.17|Phycisphaerales bacterium|TrEMBL
MHVTGLTTGRRHEKRPSTGGSAPTPARRVLERAADALFAKQHHDGHWCAELEGDSILGSE
YLLMKAALGQDEGPSATREDLRRFPLILEHLRRLQRADGTWGQYPGSPPDLSATVKAYFA
LKLFGESADAPHMRRARDAALALGGADRINTFSMFYLACLGQVSWDACPVIPPEVVLLPR
ASPFHLSKVSAWTRTMIVPLAVCTALRPVRTLPRERGIDELFIDPAARARLHRSHDGRDP
ISWNKVFLWIDGAIKALQQARLTPGRGRALRECERWLLQRVDPRTTDGLGAIFPPMVYIQ
IALKAMGYERDHPVIRRCEHELDRFLVEADDHIRIQPCFSPVWDTGIALYALTECGRTIE
NDDRIARTALWLCDREVQLVGDWAHNLRPGDRAELLHSGAERVWGAWAFEYRNDWYPDVD
DTAMVCKALWRASAGSSPDSGAARQAREAALRGIRWILAMQNDDGGWAAFDRTTHRAWME
HVPFADHNAMQDPSCADITGRTIEALITCGVPRTHAAVRRAVDFLLREQRREGCWWGRWG
VNFLYGTWQAVGGLTAAGEDPRSGHLRRAADWLLSMQNEDGGFGESANSYLEDRPAPPDR
ARAPSTASQTSWAMCALMFLRGARDPAVERAAAYLINTQLDADSPADPPTFLHDEPAGSW
REPWFTGTGFPKVFYLRYHLYRHYFPVMALGRYCRLRGE
>A0A0H3G8D2|squalene-hopene cyclase|EC 5.4.99.17|Zymomonas mobilis subsp. mobilis (strain ATCC 10988 / DSM 424 / LMG 404 / NCIMB 8938 / NRRL B-806 / ZM1)|TrEMBL
MGIDRMNSLSRLLMKKIFGAEKTSYKPASDTIIGTDTLRRPNRRPEPTAKVDKTIFKTMG
NSLNNTLVSACDWLIGQQKPDGHWVGAVESNASMEAEWCLALWFLGLEDHPLRPRLGNAL
LEMQREDGSWGVYFGAGNGDINATVEAYAALRSLGYSADNPVLKKAATWIAEKGGLKNIR
VFTRYWLALIGEWPWEKTPNLPPEIIWFPDNFVFSIYNFAQWARATMVPIAILSARRPSR
PLRPQDRLDELFPEGRARFDYELPKKEGINLWSQFFRTTDRGLHWVQSNLLKRNSLREAA
IRHVLEWIIRHQDADGGWGGIQPPWVYGLMALHGEGYQLYHPVMAKALSALDDPGWRHDR
GESSWIQATNSPVWDTMLALMALKDAKAEDRFTPEMDKAADWLLARQVKVKGDWSIKLPD
VEPGGWAFEYANDRYPDTDDTAVALIALSSYRDKEEWQKKGVEDAITRGVNWLIAMQSEC
GGWGAFDKDNNRSILSKIPFCDFGESIDPPSVDVTAHVLEAFGTLGLSRDMPVIQKAIDY
VRSEQEAEGAWFGRWGVNYIYGTGAVLPALAAIGEDMTQPYITKACDWLVAHQQEDGGWG
ESCSSYMEIDSIGKGPTTPSQTAWALMGLIAANRPEDYEAIAKGCHYLIDRQEQDGSWKE
EEFTGTGFPGYGVGQTIKLDDPALSKRLLQGAELSRAFMLRYDFYRQFFPIMALSRAERL
IDLNN
>A0A6I4Z0S3|squalene-hopene cyclase|EC 5.4.99.17|Saccharibacter sp. 17.LH.SD|TrEMBL
MMGAAVVEQAITGAHAALDKLQKDDGHWVFELEADATIPAEYIILEHFLDRINPTVQQKM
AVYLRRIQGDHGGWPLYHDGGFDMSATVKAYFALKAVGDDPEEPHMRRARAAVLQHGGAE
RSNVFTRITLATFGEVPWKAVPVMPVELVLLPRKALFSIWNMSYWSRTVVTPLLVLGARK
ALAKNPKKIHVQELFVTPPAKIKDWIRGPYRSVWGCLFKYLDSFLRPIVPHFPKTLHEKA
IRQAVSFTEERLSAGGLGAIFPAMAGVMMMYRTLGVSDDNPKVKEAWQALQDLIVEKGDE
MYCQPCVSPVWDTGLAGLAMIEAASGPQATKREETMAALKKTASWLRDHQILDVKGDWAV
NAPNLRPGGWAFQYENDYYPDVDDTAVVGMLLHRIDPVENHKAIERAREWIIGMQSSNGG
WGAFDIDNDLEALNHIPFADHGALLDPPTADVSARCISFLAQLGHPEDRPVIERGLAYLR
SEQEADGSWFGRWGTNYIYGTWSVLCALNIAGVPHNDPMIKRAADWLESVQNADGGWGED
CASYEGATPGRYKESLPTQAAWAVLGLMAVGRRDSEAVKKGIEYLVKTQDENGEWHEEPF
NAVGFPKVFYLHYHGYRQFFPLTALSRYRNLGASNSGRVEYGF
>A0A852ZG17|squalene-hopene cyclase|EC 5.4.99.17|Actinopolyspora biskrensis|TrEMBL
MTGSLRQTETVEPDAHGTETSPETGERSRTVLADRGDTRWESGEPDWLAAMEAARDHLLS
LQHEHGWWKGELQTNVTMDAEDLMLRRFLGILTAEEAAESARWVRSQQRSDGTWGTFYGG
PGDLSVTVEAYVALKIAGDDVAEEHMASARDWILRQGGVERTRVFTRMWLAMFGQWSWDD
LPTMPPEIVFLPSWFPLNLADWGCWARQTIVPLTVVSTLRPQRELGVRTEELRTGGPTGR
LQQGSSSSAWDTVFHTLDRVLHGYDRHPVRPLRRQAMRRAAEWIVARQEADGCWGGIQPP
WVYSIIALNLLGYPLDHPVLRTAITGLEGFLIREDTEEGRVRRMEACQSPVWDTVLGIQA
LHDAGVPGEDPAMHRALEYVRGEEIMVRGDWAVRRPTLPGGGGWAFEFENDGYPDIDDTA
EVLLAFTRTGHAEQDRVASAVSRGRRWLRGMRSKDGGWAAFDADNTRWLVNKLPFCDFGA
VIDPPSADVTAHVVEALVETGDRDDPVVRDGVRWLLENQEGDGSWYGRWGVNHVYGTGAA
VPALVRAGIPTEHHALRRAVRWLEDHQNPDGGWGEDLRSYDDPAWIGRGDSTASQTAWAL
FALLAVGRHDTRAVRGGIAFLVATQQPGGYWSEPQFTGTGFPGDFYINYHLYRQVFPLAA
LGRYRRAVRGE
>A0A832HBW0|squalene-hopene cyclase|EC 5.4.99.17|Phycisphaerae bacterium|TrEMBL
MTAISRTHADAASLGGPTSSSAPLTARLGELLPDQSFLQGADQTLARAFAALVAKQHQDG
YWCAELQGDSILESEYILLKFILGQESDPDLPPIGNYLRSLQQSDGGWNMYPGGANDLSG
TVKAYFALKLLGDDPDAPHMIAAREQVLKLGGAENCNSFTKFYLAALGQISYDACPSIPP
EIVLLPKFLYFNLYAVSAWSRTMILPLAIVSTLRPVRQLPAEQGISELYKDMSAANSISG
RLKGLPRSWREAFLLIDMTLKRYEKTSVTPLRPLAIREAEKWIIEHMNGSEGLGAIFPPM
VYVLIVFKALGYPDDHPKVLEAQKHLKDLFIREADAIRIQPCFSPVWDTGIALHAMAEAG
LKPEDEVAAKTTKWLLGKECRNASDWSKNCPGVEPSGWFFEFANPHYPDVDDTAMVIMAM
KRAGGDVAAPAIKRGVNWLLAMQNDDGGWAAFDRTKNRAVLEHVPFADHNAIQDPSCPDI
TGRVLESLGHNGITTQHPAVRKAIDFLKETQEKEGCWFGRWGVNYIYGTWQVLAGLRSVG
ERMDHKYIRRAAEWLRGVQKPDGSFGESCDTYENPSLKGRGPSTPSQTAWGAMGLMAVAG
HGTFTDPHIRKAIQWLIDNQTEDGNWDEAYYTGTGFPRVFYLKYHLYRLYFPLMALGRYK
RLVQR
>A0A3N6NZ29|squalene-hopene cyclase|EC 5.4.99.17|Okeania hirsuta|TrEMBL
MTEKNKFKQSILASQKYLLNLQKTEGYWWGELESNVTITAEIVLLHKIWQTDNKRPLEKA
KNYLISQQREHGGWELFYGDGGDLSTSIEAYMALKLLGVAKTDPSMLKAQDFIIKKGGIS
CSRIFTKLHLALIGCYNWQGIPSIPPSIMLLPEDFPFTIYEMSSWARSSTVPLLIVFDKK
PIFSVNPTINLDELYAEGINNASFELPRQYDLTDLFLGLDKAFKFAENFNLMPLREEGLK
AAEKWILERQEVTGDWGGIIPAMLNSMLALRCLEYDVADPVVVRGLEAIDRFGIETEDSY
WVQPCVSPVWDTAWVIRSLVDSGIPPRHPAVVKGGEWLLQQQILDYGDWAVKNKLGKPGG
WAFEFINRFYPDIDDTAVVVMALDAVELPDEELKRVAIARAMEWVASMQCQPGGWAAFDV
DNDQDWLNGIPYGDLKAMIDPNTADVTARVLEMVGCCGLSMDSWRMKRAIAYLEREQEGE
GCWFGRWGVNYIYGTSGVISALAVVAQESHRDFIEKGASWLVGCQNSDGGWGESCWSYND
PSLKGKGKSTASQTAWALIGLLAAGEATGNFAREAIDRGVDFLVSTQNDDGSWLESEFTG
TGFPCHFYIKYHFYPQYFPLMALGRYENLLSG
>A0A4D8Q933|squalene-hopene cyclase|EC 5.4.99.17|Azospirillum brasilense|TrEMBL
MQDHNASTTLRVQRAEPSAKAVSDAVAEATDALIRRQQADGHWVFELEADATIPSEYLLL
HHILDEIDPELEAGLAAFIRGRQGRDGGWPLFFGGAMDISCSVKAYFALKAAGDSPDAPH
MRRAREAILARGGAARCNVFTRILLAQFGQIPWRAVPAMPVEVMNLPPWSPFHISRISYW
SRTVVVPLLVVMAHRLRARNPRGIGIAELFTEPPERVRNWHSNNSRGGWATLFRALDAAL
HAVEPRLPANGRQTAIDRAVRFVTERLNGEDGLGAIFPAMVNAVLMFHCLGMPPDHPDAA
MARRALHGLVVRQPGRVYCQPCLSPVWDTAIICNALLETGSPLARAAARRGADWLIDRQI
LDVEGDWAWQRPGLASGGWAFQYNNAHYPDTDDTAMVVMALQRLDADRYGEPIRRARDWI
VGMQSRNGGWGAFDAENQHDFLNHIPFADHGALLDPPTSDVTARCVMMLARLGEGRDTVP
TRRGLTFLEREQESDGAWFGRWGTNYVYGTWSALEALNAAGVPHSAVAVQRAAQWLLAHQ
RADGGWGEDGASYWAGNPRGEGPVSTASQTAWALLGLMAAGKGNHPAVDRGVEYLLSARD
TEGLWSEEPFTAVGFPRVFYLKYHGYAASFPLWALARYRALRA
>A0A6B8MBC4|squalene-hopene cyclase|EC 5.4.99.17|Methylocystis parvus|TrEMBL
MNVAARIENFAPVGPEALEASIQSAKRALLADGKADGHWCFELEADTTIPAEYVLMRHFR
AEPVAEELERKIAVYLRRMQGGHGGWPLFQDGAFNISASVKAYFALKMIGDDVDAPHMVR
AREAILAHGGAATSNVFTRALLALYGEIPWRGVPVMPVEIMLLPRWFPFHLDKISYWGRT
VLVPLLVLMTKRPQARNPKGVRIQELFTTPPEEVKVWPKGEHQTWPWAHLFGEIDKLLRL
VEPHMPKRSREYSVQLAERWTTERLNGVDGLGAIFPAMVNSLLMYDALGIAETDQRVKDA
RESIERLLVVGETEAYCQPCVSPVWDTSLVAHALLETGGEDARERARAACDWLAPLQVLD
VKGDWAAQRPDLRPGGWAFQYANAYYPDVDDTAVVATAMDRLTSAEEKKPYAERIARAKE
WIVGMQSKNGGWGAFDADNAYHYLNHIPFADHGALLDPPTVDVSARCVSMLAQLGDKVET
SDCLKRGVDYIIREQEKDGSWFGRWGANYVYGAWSALCALNAAGLPHSHESYRRAVSWLV
AIQNPDGGWGEDLSSYKMDYKGYEPAPSTSSQTAWAILGLMAAGEVDHPAVARGVAYLQA
TQAEHGLWDEPRFTATGFPRVFYLRYHGYRRFFPLWALARYRNLLQTNSKAVTVGL
>A0A5E6MGT8|squalene-hopene cyclase|EC 5.4.99.17|Methylacidimicrobium cyclopophantes|TrEMBL
MRSGKLFSQPSEGKTKTKPVLVIEETLDHAQAVGLAVARAQSYLLSTQKPDGHWVGELFA
DVTLACDRILLMHWLGKVDYRKQARFVKHILDRQLPDGGWNIYPGGPSELNATIKAYAAL
KLAGFAPEDPVMERARSTILRLGGIPKSMTYTKLGLALLGIYPWHQLPVIPPEIMLFPSW
FPFHLYKMSAWTRTMLVPLMIIHHFKPTRQLPLHLQLHELFPAGAEQEGLSWIWSAKLFS
KRNFFLLCDKLLQLWDRSPWKPLRARALKKAEEWLTQRMGAGSDGLGAIFPAMHYAIVAL
KALGYPEENPLYQKAVRDFEGLEVDEGEERDFRVQPCLSPVWDTAVAGVALSKSGLPLDQ
AELRKAAAWLMEREIQVRGDWYVNNPHPECSGWAFEYNNVYYPDVDDTLMVLLALLRIET
EDEERKREVIDRAFRWVVSFQCRNGGWAAFDKDVNSPWLEDVPFADHNAILDPPCSDITA
RALELAGMLGVKRTEPFVQRGIRFLRETQESDGSWFGRWGVNYVYGTWQALRGLRAIGED
MNQQWILRARDWLESCQNEDGGWGETPDSYENPQLKGRGPSTASQTAWAIMGILACGEAD
RPSVRRGVSYLLRKQDPDGSWPEEFLTGTGFPGVFYLKYDMYRNAWPLLALSEYAKALSA
AKEQTEAWVRATLSVAVRSRSSAGGIG
>A0A4P7L5R7|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus oxalaticus|TrEMBL
MSINETALGTTAPPVRVAADPAFAPAFAQRSAAQELDHGIGLAVDALLHQQRPDGHWVYE
LEADATIPAEYVLLVHYLGEAPDLALEARIARYLRRIQNADGGWPLFHDGKADISASVKA
YFALKMAGDDPQAPHMARARQAIHAMGGAEASNVFTRTLLALYGVMPWSAVPMMPVEIML
LPRWFPFHLSKVSYWARTVIVPLLVLNSLRPRARNPRGIGIDELFSNPRRSVGLAPRAPH
QHAGWYNLFRGLDALLRVAEPAFPRVLRRRAIAAAQRFVRERLNGEDGLGAIFPAMANSV
MMFDVLGVPADDPARAVARHSVERLLVEHGDEAYCQPCLSPVWDTALAAQALLETGEARA
AAAVGRALDWLKPLQVLDVRGDWSVRRPRVRPGGWAFQYANAHYPDVDDTAVVAAAMDRY
MREHATPGRYDEAVARAAEWIVGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDPPTA
DVSARCLSMLCQTGATPASSEPAARALRYLLAEQLPDGSWFGRWGTNYIYGTWSALCALN
AAGLGPDAPAVRRAADWLAGIQNDDGGWGEDGASYRLDYRGYEAAPSVASQTAWALLALM
AAGAVQHPAVARGIGYLLRTQRPPQEGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWAL
ARYRNLRRGGDGGGGGEGVAEGRVAWGL
>A0A552ER91|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa Ma_MB_S_20031200_S102|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYPDGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPTLEKAREFI
LAQGGISKTRIFTKMHLALIGCYDWLGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNNWSDVFLWLDGLFKWTEKTNLVPFR
QESLQAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVDDPIVVRGLKAVDNFAIQ
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKGVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYSDLKAMIDPNTADVTARVLEMLGTCDVNIEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEANKYHHQLQKGANWLSGCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A5M7BY25|squalene-hopene cyclase|EC 5.4.99.17|Saccharopolyspora hirsuta|TrEMBL
MIPDPRTALVAARDHLLSRQHPDGWWKGELETNVTMDVEDLLLRQFLGIRTAVETEQAAR
WIRSQQRSDGTWANFHGGPGDLSTTVEAYTALKLAGDDVDAEHMTAARNWILEQGGLEAT
RVFTRIWLALFGEWSWDELPAMPPEVVLLPSWFPLNVADWACWARQTVVPLTVVCTLRPR
RDLGITVRELRTGRPRPPVRAEWSWKYGFHLLDRVLHRYQKHPLRTLRKHAMLRAAEWIV
ARQEADGSWGGIQPPWVYSLLALHLLGYPMDHPVLRQGLAGLERFLIREQTADGVVRRLE
ACQSPVWDTVLGMQALHDAGVPSAHPALRRATDFLLAEEIRVKGDWSVRRPHLPAGGGWA
FEFENDGYPDIDDTAEVLLALNRMDHPDRVAVQGAIERGTRWLRGMQSADGGWGAFDADN
TRQLIRKLPFCDFGEVIDPPSADVTAHVVEALAALGHDEEVVQRGVKWLLRNQEKDGSWF
GRWGANHVYGTGAVVPALVRAGIKPEHRALRRAVKWLEKHQNPDGGWGEDLRSYDDPAWI
GRGDSTASQTGWALLALLALGRHKTDAVQRGVQYLARTQRPDGGWDEPQFTGTGFPGDFY
INYHLYRVIFPLTALGRYHRAGE
>B1Z2I6|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia ambifaria (strain MC40-6)|TrEMBL
MNDLTEMATLSAGTVPAGLDAAVASATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGRYLRRVQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPIAKNPRGVRIDELFVDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AADGLFPNYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKSIEKLLVVHGDEAYCQPCLSPVWDTSLAAHALLETGDARAEEAVIRGLEWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANPHYPDVDDTAVVAVAMDRVQKLKHDDAFRDSIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCALNAAGLTPDDPRVKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGVEYLL
AEQKEHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRNNATRVTFGL
>A0A852ZUU6|squalene-hopene cyclase|EC 5.4.99.17|Actinopolymorpha rutila|TrEMBL
MAGLSPYPEYHKAPEPQKHPDDDAQAHAALERAVEHLLDLQDPAGWWKGELETNVTMDAE
DLLMRQFLGVRTDEQTTQSAAWIRSQQRDDGSWANFRFGPGDVSTSVEAYVALRLAGDDP
DDQHLKQARQFILDNGGVEAARVFTKIWLSLFGEWSWDDVPALPPEIVLAPHWVPFNVYD
WGCWARQTLVPLTILGALRPNRPLGVSIDELRTGTPEPPPDRATTWRGAFARLDRALHRY
ERHPVRSVRRLALRRAAEWVVARQEKDGCWGGIQPPWVYSLMALHALGYPLDHPVLTAGL
AGWERFTIREDTPHGTVRRIEACQSPVWDTALALVALGDAGVDPEAGPMVRARDWLLAEE
ITVRGDWSVRRPRTPAGGWAFEFDNDGYPDTDDTAEVVLGLRRTAETPRLEEAVRRARVW
LRGMQCRDGGWGAFDADNTRELAYQLPFCDFGAVIDPPSADVTAHVVEMFAHEGHADDPE
VQRAVRWLLDAQEADGSWYGRWGANHVYGTGAVLPALVAAGLSRHDRAVVRGANWLTAHQ
NADGGWGEDLRSYSDPSWVGRGTSTASQTAWALLALEAAGLRDSPAVRAGIAWLVATQRP
DGGWDEPQFTGTGFPGDFYINYHLYRLVFPVTALGRLLAPAGDPQDRA
>A0A7W7WMV2|squalene-hopene cyclase|EC 5.4.99.17|Micromonospora polyrhachis|TrEMBL
MPSPLIDRVSRAIEAGAEELLGGQRPDGAFVDSPPSSVLGTAGAVTALHRADREGSRDLV
ARGVAWLCAHQHGDGGWGGVVGADSEPIATSVATATLQIVAPTDSAEAVRRGRQRLAALG
GVEAVTDPAVNHLCRQFLALTNLPEAGQLRRLPLELVHFDGLRRQRISFRTAPFVALALL
QTRTMPAGPLRRATLRRAEPVALRLLAAIDAHEGHTGAFSEDPWPAALVCLGLAHADLAP
HLVSAIAGFLRRAVRPDGSWDAVTNLDLTRSGFAATGLIAAGYADDPRLGRTRDLFHRCQ
QRQPFPVFGVPPGGWSFSGPRGWPVTLESAEIVTALAGLPDHHDDPVLRRGVDWLINRQD
RRGSWSLWVRDTRLANDGPCCGITSQGIVALRHTGHAPDSPPVVAAVRWLLTQQRPDGTF
ENLWYRDHTSGTAMVLDALAEAGQTTHLVSVRARDWLLRTQLPDGSWGSGSTPEGTVEET
AWTVHALLSAGAAATDEPVTRAVGWLLDTQLSSGAWPASRVCAYIRHHMHYPNGAITRGL
ALRALGAYRSHTGGAA
>A0A0J7JRU6|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Burkholderia pumila|TrEMBL
MNDLSLPAVAAPMPNKSAALEQAVSKATAALLAAQRPEGYWLYELEADATIPAEYVLLVH
YLGEEANVQLEEKIGRYLRRIQRADGGWPLFHDGAMDVSASVKAYFALKMIGDSPDAEHM
VRAREAILAVGGAAKVNVFTRILLALFGVVSWCAVPMMPVEIMRLPMWFPFHLSKVSYWA
RTVIVPLLVLNAKRPLARNPRGVRIDEIFIDPPVNTGMLSRSGHQNRGWFAFFRVVDSVL
RTVDGVLPKAGRESAIDEAVRFVDERLNGEDGLGAIFPAMANSVMMYDVLGYPPEHPSRA
IARKSLDNLLIVDEADDGEAYCQPCLSPVWDTSLAAHALLETGMPKVRAAVARCLEWLLP
LQILDVRGDWISRRPNVRPGGWAFQFANPHYPDVDDTAVVAMAMERADRENGTAICGEAI
ARGREWIVGMQSSDGGWGAFEPENTQFYLNNIPFSDHGALLDPPTVDVSARCLSMLAQLG
ETPANSEPARRALNFILKDQLRDGSWYGRWGMNYVYGTWSALCALNAAGIAPTNARVKRG
ADWLVSIQNADGGWGEDGNSYKLDYREYEQAPSTASQTAWALLGLMAAGRVDDPSVQRGI
DWLVRTQNEEGVWNEALFTATGFPRVFYLRYHGYRKFFPLWALARYRNLTRDGETRVTEG
M
>A0A7S7NWG6|squalene-hopene cyclase|EC 5.4.99.17|Paludibaculum fermentans|TrEMBL
MSPGLQVEDALLTASAKAARSASEYLLSRQDPAGYWWGDLTADSTLESDWLLLLLWLHPP
KNGQWVPPDRAKVDRAVASILARQNADGGFAIFAKGPSECSASVKAYFALKLAGLGVDDT
RMSRLRERILSLGGIQAANSYVKINMALFGLFPRQHVPSVPPEIMLLPANLLYEMSSWTR
AIVVPLSIVQANTLGKPRPVPDGFDLSELFKPGADITFHKADSFFSWKNGFLMADKLVKV
WERQAPGSIRAKAIGKAKDWILERFRHSEGLAAIYPSMQYAIMALDSLGYTADSPERVEA
QKQFDALLVDDGKRFFFQPCFSPVWDTAIAAYSLGVGGFAPDDRMKQCGDWLLSKEVRQK
GDWSVKRPDTQPSGWYFEFANEFYPDIDDTAMVLLALWHTRSSRQGEFDAAAGRAIDWLL
AMQSKDGGWAAFDVDNDTHSLSEVPFADHNAMLDPTCPDITGRVLEALCLWGVSQDSPAV
RRGVQYLRKSQEPDGSWYGRWGVDYIYGTFLALRGLRAAGYDEREAEVLRAGEWLRSVQN
ADGGWGESCESYARNTFVGAESTASQTAWAVLGLLAGGDTTSESVHLGIDFLVRNQRPDG
GWDEDLATGTGFPRVFYLTYHLYRHSFPALALAEYMKIKGGRGAGHP
>E6TY67|squalene-hopene cyclase|EC 5.4.99.17|Evansella cellulosilytica (strain ATCC 21833 / DSM 2522 / FERM P-1141 / JCM 9156 / N-4)|TrEMBL
MEIRDKLTNFQQQLIEDVRVKQLNDGQWKFPCESGPLTDAYMIVLLKLIDTRHEHLIKQL
VDRLLYTQANNGAWKLYEDEKDGNISATIEAYTALLFSRKIDEHDERLVKAKRFIYRNGG
LKAAHVSTKFFLALNDLYPWPTIFPLPTWLLFMPSHIPISFHNMTSYVKIHFASVFILAS
KQFSIRTPNTPYIDDLIMESKVRKRLKKQRNGKKRRFHFSRINNAANLRAEKYILERLEA
DGTAGSYATATCMMIYSLLALGYRSDSPIIRHAIHGLQKLTVQINGKTHMENAESVVWDT
SLLLYVLQESGFAIEDEHVKKGGEFILRQQQKTNENGAWGFSQNNSFYPDVDDTQACLRA
LQSLADKDSTYRECWYNGLKWLLNMQNKDGGWASFNKNRRNHFVKHLPIENISDTAIDIS
TADLTGRVVQFLGNNVKMTINHPKIKKAVQWLLKNQEKDGSWYGRWGVCYIYGTWAAVTG
LLSVGVSENDPAIQKAKKWLLSIQNKDGGWGESCSSDVHKKYVPLSWSTPSQTAWALDTL
IAICDEPNETIRRGIEHLMERKGNFTYPTGGGLPGNFYLTYHSYNSIWPLLAIAHFRKKY
MK
>A0A3M8DUD8|squalene-hopene cyclase|EC 5.4.99.17|Brevibacillus nitrificans|TrEMBL
MQTVLLQKQAQDGSWRFCLESGTLTDTHMIILLRTLGIHDEELMLGLANRIAGKQQPNGA
WKLYTDEADGNLSATIDSYFALLFSGYLKKTDPRMEMAKSFIRANGGLNGANMLTKISTA
LTGQYQWPQHFMVPVELTLLPPTSPLSFYDFVGYARVHLAPMMIFADRKYVFHNPATPDL
SDLYVGPAISPGIYPHRRMEQFAQDAQGFLASIHSFVRTLPFLPSVLREVSLRRLETYIL
ERIEPDGTLYTYSTSTFFMIFALLAQGYPLQHPKIRHAMQGLQAAVYRTSEDAHLQLATS
AVWDTALLTYALQHSGIESSHPSLQRSLKYLLGKQQTTYGDWKIRNPHAAPGGWGFSDQN
TMNPDIDDTTAALRAISMQAKADQTTAAAWKRGLDWLMTMQNDDGGWPAFEKNTNSAVIR
QLPIEGSDTVSIDPSSADLTGRTLEFLGNYAGIRMNHPQVQKAVRWLLSEQRPDGSWYGR
WGIAFLYGTWAALTGMMAVGVPADSEAVQKAVSWLIRNQNEDGGWGESCKSDEKQAYVAL
GASTPSQTAWAVDALISVFPKPHPAVERGIQYLLQFKDRHDWTTAYPTGGGRPGGIYFAY
HSYRWIWPLLALSHYRDKYGTNQPYS
>B1T1Y1|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia ambifaria MEX-5|TrEMBL
MNDLTEMATLSAGTVPAGLDAAVASATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGRYLRRVQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPIAKNPRGVRIDELFVDPPVNAGLLPRQGHQSPGWFAFFRVVDHVLR
AADGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKSIEKLLVVHEDEAYCQPCLSPVWDTSLAAHALLETGDARAEEAVIRGLEWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAVAMDRVQKLKHNDTFRDSIALAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCALNAAGLTPDDPRVKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGVEYLI
AEQKEHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNATHVTFGL
>A0A0H3KQ00|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia multivorans (strain ATCC 17616 / 249)|TrEMBL
MIRAMNKSALSPWSALDTAIARGRDALARLQQPDGSWCFELESDATITAEYILMMHFMDR
IDDALQERMARYLRAIQRLDTHGAWDLYVDGAPDVSCSVKAYFALKAAGDSEHAPHMIRA
REAILKLGGAARSNVFTRILLATFGQVPWRATPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNVAIPELFVTPPDQERHYFPPTRGMRRAFLILDRVVRHVEPL
LPKRLRRRAIRHAEAWCAQRMNGEDGLGGIFPPIVYSYQMMDVLGYPEDHPLRRDCENAL
AKLLVTRPDGSVYCQPCLSPVWDTAWSTMALEQARSVAVPESDESARALDELDARIARAY
DWLATRQVNDLRGDWIENAPADTQPGGWAFQYANPYYPDIDDSAVVTAMLDRRGRTHRNA
DGSHPYAARVARALDWMRALQSRNGGFAAFDADCDRLYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTRRAEDRASLARAIDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLTLAGED
PSQPYIARALEWLRAHQHADGGWGETNDSYLDPALAGTNGGESTSNCTAWALLAQMAFGD
CASDSVKRGIAYLQSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GAAEARARASSGRAPHAADTALA
>C6E1N3|squalene-hopene cyclase|EC 5.4.99.17|Geobacter sp. (strain M21)|TrEMBL
MTSPFKHPISNALTSFNGNFAEPEQCVEQQTGAKVHHLPASIWKRKMGKAKSPLDVAIEG
SRDFFFQEQLPKGYWWAELESNVTITAEYIMLFHFLGLVDRERQRKMSNYLLSKQTEEGF
WPIYYGGPGDLSTTIEAYFALKLSGYPADHPALAKARAFILEQGGVVKSRVFTKIFLALF
GEFEWQGVPSMPVELNLLPDWAYINIYEFSSWARATIVPLSVVMHSRPVRRVPPSARVQE
LFVRQPTAADYSFAKNDGIFTWENFFLGLDRVLKVYEKSPLRPFKNMALAKAEEWVLEHQ
EPTGDWGGIQPAMLNAVLALNVLGYQNDHPAVEQGLRALANFCIETEDQLVLQSCVSPVW
DTALALKALLDAGVPPDHPSLVKGAQWLLDKEVTRPGDWRVKSPALEPGGWAFEFLNDWY
PDVDDSGFVMIALKGIQVKDRKSMDAAIKRGINWCLGMQSKNGGWGAFDKDNTRHVLNKI
PFADLEALIDPPTADLTGRMLELMGTFNYPITLPAAQRAIEFLKKNQEPEGPWWGRWGVN
YLYGTWSVLCGLAAIGEDMDQPYIRKAVNWIKSRQNIDGGWGETCQSYHDRTLAGVGEST
PSQTGWALLGLLAAGEMHSATVVRGVQYLISTQNSDGTWDEQQYTGTGFPKYFMIKYHIY
RNCFPLMALGTYRTLTRTQP
>A0A6P0PFI6|squalene-hopene cyclase|EC 5.4.99.17|Okeania sp. SIO2F5|TrEMBL
MTEKNKVQQSILASQEYLLNLQKPQGYWWDELESNVTITAEIVLLHKIWQIDNKRPLDKA
KNHLISQQREHCGWELFYGDGGDLSTSIEAYMALRLLGVAKTDPIMLKAQDFIIKKGGIS
CSRIFTKLHLALIGCFNWQGIPSIPPSIMLLPEDFPFTIYEMSSWARSSTVPLLIVFDKK
PIFSVNPTINLDELYAEGINNATFELPRQYDWTDLFLGLDKAFKFAENFNLMPLREEGLK
AAEKWILERQEVTGDWGGIIPAMLNSMLALRCLEYDVADPVVVRGLEAIDKFAVETEYDY
WVQPCVSPVWDTAWVIRSLVDSGIPPSHPAVLKAGEWLLQQQILDYGDWAIKNKLGKPGG
WAFEFINRFYPDIDDTAVVVMALDAVELPDEELKRVAIARAMEWVASMQCQPGGWAAFDV
DNDQDWLNGIPYGDLKAMIDPNTADVTARVLEMVGCCRLSMDSWRVKRAIAYLEREQEGE
GCWFGRWGVNYIYGTSGVISALAVVAQESHRDFIEKGASWLVGCQNSDGGWGESCWSYND
PSLKGKGKSTASQTAWALIGLLAAGEATGNFAREAIDGGVDFLVSTQKDDGSWLESEFTG
TGFPCHFYIKYHFYPQYFPLMALGKYENLLSG
>A0A423V6I3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces globisporus|TrEMBL
MTATTDGSTGAANITGSPADDPTDTRTAAEDVTDVARQAAERSVKHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPGTTRAAALFIRGEQLGDGTWNTFYGGPGDLSATIEAY
VALRLAGDRPDEPHMARASGWIRDQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPDHPNPPRKLAPPTSW
DGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMIEACQSPVWDTCLATIALADAGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARLESAIARGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLANHPRTREGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALITAGLPAGHP
AIRRAVDWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDTASV
TRGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRP
DAAEEA
>A0A840HEV9|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. ERR14|TrEMBL
MDSVNATSREALQPGTLQPGILQSGILESSIASATQGVLDFQQADGHWVFELEADCTIPA
EYVLLRHYLAEPVDAVLEAKIANYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGD
PVDAPHMVRAREAIHARGGAIHSNVFTRFLLAMFGVVTWRAVPVLPIEIVLLPFWSPFHL
NKISYWARTTMVPLMVLAALKPLAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFVLF
RSLDAVLRVIEPMFPKALRKRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKD
ENFPPRAITRRGIDKLLVIKDDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLD
WLIPKQELELKGDWAVKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGATGY
DAAIDRGREWIEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISML
AQLGETEKTSKHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDHKDPM
IRKAAGWLASIQNEDGGWGEDAVSYRLDYRGWEAAPSTASQTAWALLALMAAGEVDHPAV
ARGVEYLIATQNKKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRV
VGVGM
>B1ZIH8|squalene-hopene cyclase|EC 5.4.99.17|Methylorubrum populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001)|TrEMBL
MREAAVSKVETLQRPKTRDVSLDDVERGVQNAARALTEMTQTDGHICFELEADATIPSEY
ILFHQFRGTVPRDGLEAKIGNYLRRTQSKVHGGWALVHDGPFDMSATVKAYFALKMIGDD
IEAPHMRAARKAILQRGGAANANVFTRILLALYGEVPWAAVPVMPVEVMHLPKWFPFHLD
KVSYWARCTMVPLFVIQAKKPRAKNPRGIGVAELFVTPPDSVRTWPGSPHATWPWTPIFG
AIDRVLQKTQDHFPKVPRQRAIDKAVAWVSERLNGEDGLGAIFPSMVNSVLMYEVLGYPP
DHPQVKIALEAIEKLVAEKDDEAYVQPCLSPVWDTALTSHAMLETGGAAAEANARAGLDW
LKPLQILDIKGDWAETKPNVRPGGWAFQYANPHYPDLDDTAVVVMAMDRAQRQHGLVSGM
PDYSASIARAREWVEGLQSADGGWAAFDADNNHHYLNHIPFSDHGALLDPPTADVTARVV
SMLSQLGETRETSRALDRGVTYLLNDQEKDGSWYGRWGMNFIYGTWSVLCALNAAGVDPQ
SPEIRKAVAWLIRIQNPDGGWGEDASSYKLNPEFEPGYSTASQTAWALLALMAVGEVDDP
AVARGVNYLMRTQGQDGLWNEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKKGNS
RQVQFGM
>A0A328U6G4|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus montanisoli|TrEMBL
MIPMNQRIQAGIDNLINRLLSSQSADGSWRLGFIEYGMSTDAAAVLLLTSAGINKPKLVS
SLRDRILAKQSDDGAWRVYPDENGGNLSATAECYFALQFAGLSASEPRMVKAREAIRNMG
GLSSIDSLLTKFMLAAVGQYEWPRWFPVPLSLLLLPQSAPVHFYKFSCYARVHMAPMMLL
GDRKPAFKLPHVEPLPSQPSTESWLNHFDRRFIEMYNNRLFDIPGLTAPTLREQGTKKAL
DFMFERLEPDGTLYCYASATMLMVQALRALGFAITDPIITRAIGGLEALLTQDNGHVTMQ
NTTSTVWDTALISHALREAGVTAAHPAIRSAGSYLLSRQHTKLGDWKLRADAEHPTPGGW
GFSDHNTINPDMDDTTAALRALEALSGIGPAGMTYQDAAERGLQWLLSMQNSDGGWAAFE
RNTNSRIIRFIPLDGAEDAATDPSTPDLTGRTLDYLGRHAGLTAKRSRFVRRAADWLYGT
QERNGSWYGRWGVCYLYGTWAALTGLTAVGESPEHPQIRRAVDWLYRVQNSDGGFGESCR
SDSVKRFSPLPYSTLSQTAWALDALTAVTAGRPTEAMERACSFLLQELNANGRAAQYPTG
AGLPGYLYTRYDSYSLIWPLLALANYRNKFAP
>A0A537RNM1|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MNDINTKEVAMLRRRVDATRLDEAIAQASESLVALQHPDGHWVFELEADVTIPSEFILLQ
HYFGRVEPELQARIAKYIRATQGADGGWPLFHGGALDISASVKAYFALKAAGDPVDAPHM
ARARAAILAGGGARRCNVFTRILLALFGEVPWRAVPVMPVEIMLLPNWSPFHIAKVSYWS
RTVLVPLLVLMALRPRARNPLGITVRELFLEPPEAVRDWIGGPTSSPLSVAFGMLDRLLR
VAEPFFPADARRRAIDKAVAFVTERLNGEDGLGGIFPAIANSAMMFDCLGYAPDHPGYAS
ALASLRKLLVLDGERSYCQPCLSPVWDTALACHALMEVEDIRLEATIRRALDWLETKQVL
EVVGDWASARPGLRPGGWAFQFENPYYPDLDDTAAVALALDRFGSSRYRVAIDRAAEWVI
GMQSRGGGWGSFDADNTHFYLNHIPFADHGALLDPPTADVSGRCLSFLTQIGYGRDHPAV
AAAIDYLRAEQEPDGSWFGRWGTNYIYGTWSVLTAFNSAGLPADSPEVRRAVDWLVARQH
KDGGWGEGGESYWTGGPHGEAPYSTSSQTAWALLALMAAGEVGNPAVARGIAYLVESQDE
DGNWDEPWYTAVGFPRVFYLRYHGYRAFFPLWALARFRRLSRGNSRQVPFGI
>A0A4U1DA17|squalene-hopene cyclase|EC 5.4.99.17|Robertmurraya kyonggiensis|TrEMBL
MNQSITDGIESLIDQLKKDQSFDGSWNYPFETGISTDCYMIILLRTLEIDDENLVKELVR
RIISKQEKNGAWKLFYDEGEGNVTATIEAYYALLYSGYFEKTGKRLTAARRFILKNGGIE
KAHMFTKIMLAITGQYKWPSFFPIPLEFLLLPNIFPINFYQLSVYGRANLLPIMILSDGK
FQLRTKKSPDLSELYIRQKDEELFQEEDWRSLYDSIHSGIESLLELPSQLKERAKSKGKQ
YMLSRIEKDGTFYSYYSSTFLMIFALMALGYKKSHPVITRAVNGLKSMKTTIDGFTHMQY
TTATVWNTSLISYALQEAGVSGEEAVIEKANNFILRKQHTLYGDWAVHNPNSFPGGWGFS
NINSFNPDVDDTTASLRSIARDAVHNPSYRSAWDRGIRWLLSMQNEDGGWPAFEKNTNSP
LFKHLPIEKADFILTDPPTADLTGRTLQFLGDFTNLPSSHPSVKAGVESILAKQEKDGSW
YGRWGICYLYGTWGALTGLSAVEVQSGHPAVRKAVSWLESVQNEDGGWGESCKSDSQKKY
VALPASTLTHTAWAVDALMSVSDKPSRAIKKGIEFLLENLEKKDWTTEYSKGQGMAGAFY
IHYHSYRYVFPLLALAHYKQKYEKS
>A0A7Y0JJJ9|squalene-hopene cyclase|EC 5.4.99.17|Actinoplanes sp. TBRC 11911|TrEMBL
MTTQVRTRATADALDDAVRYLRGLQDEAGWWKGELQTNVTMDAEDLLLREFLGIRQEEET
AQAARWIRSQQRDDGTWASFEGGPPELSCTVESWVALRLAGDAVAEPHMRRAQEWILAHG
GVEKTRVFTRIWLALFGLWSWADLPNMPPEFVFLPKWFPLNKYNWGCWARQTVVPLTIVS
TLQPVRPLPFGIDELRTGRRVKPTGAVWTWKGAFNRLDKVLHAYAKKPLKGLRQKAIDQS
VAWILARQEADGGWGGIQPPWVYSLLALHLLGYPLDHPAVKKGLDGLDGFLIRESTPDGV
VRRLEACQSPVWDTGLAVIAMLDAGVPADDPAIAKAADWLVGEEITVKGDWSVRRPALAP
GGWAFEFANVNYPDTDDTAEIVLGLRRVAGDNPAMRAVVDRAVDWTVGMQSKDGGWAAFD
ADQLSALPTKLPFCDFGAVVDPPSADVTAHVLEMLAAEGKADRAPARRGIAWLLKNQEDD
GSWFGRWGANHVYGTGAVVPALVEAGVDPASPPIRRAVRWLLEHQNEDGGWGEDLRSYVD
VAWRGRGTTTASQTAWALLALMAAGGADAAVERGVAWLVESQEVDGSWDEPQFTGTGFPG
DFYLNYHLYRIVFPITALGRYVASRS
>A0A7V6QPS1|squalene-hopene cyclase|EC 5.4.99.17|Bacillales bacterium|TrEMBL
MELIEKVKNDQSPEGYWNYTFETGIITDCYMIILLRSLEIEDENLVKELSEKILRKQQEN
GAWKLFHDEPNGNLSDTIGAYYALLYSGYYSKNDPRLRKAGQFIKANGGMDKSNMFTKVM
LALTGQYRWPSFFPIPIEMILLPVSFPINFYSFSVYGRVNLAPVMILADKKFRIKTSKSP
DLKDLLVHREEAEQEHSFGFRESEEFRSISSFINQGIKSLIGLPSHVHKLATEYTKQYML
SRIEPDGTLLSYFSSTFLMIFALLSLRIPKSDPIIVNAVKALKSMKSVGINGLPHMQFTT
ANVWNTSLLTYALQEAGISSNDIVIKKANNYLLNKQHYKYGDWAIHNPSALPGGWGFSES
NTIHPDVDDTTASLRAIARNVRKDWRDRQAWDRGIQWVLSMQNDDGGWPAFEKNTNSKIL
HLFPIEKAEYFLSDPSCADLTGRTLEFLGTYTNLSKTHPSISRGVEWLRKNQENNGSWYG
RWGICYIYGTWGAVTGARAVGISPSDPMISKAVKWLEEIQNSDGGWGESCQSDLNKKYIP
LGSSTLTHTAWAVDALIATSDKPTKVIQRGIEFLLGNMNREDWTTNYPKGAGMAGDFYIH
YHSYRYIFPILTLAHYRKKFS
>A0A7Y0B6I6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. R302|TrEMBL
MTATTDGNAGALGPLAPAASTTPPHTATSPASLDEAAARAVRAATDHLLARQAPEGWWKG
DLETNVTMDAEDLLLRRFLGISDPDTTAAAARHIRSRQYEDGTWPTFHGGPGDLSATVEA
YVALRLAGDRPEAPHMARAAAWARAEGGIAATRVFTRIWLALFGWWRWEDLPELPPELMF
LPKWFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPDLPAPKRPLAPLTG
WDGLFQRLDRALHVYHRFAPRGPRRAAMNTAARWIVERQENDGCWGGIQPPAVYSLIALH
LLGYDLEHPVMRAGLESLDRFAVWSEGPEGPVRMVEACQSPVWDTCLATIALADAGLPAD
HPALVKAVDWMLDEEITKPGDWAVRRPGLPPGGWAFEFHNDNYPDIDDTAEVILALRRVR
HPDPARVDAAVARAARWTAGMQSGNGAWAAFDADNTGVLPNKLPFCDFGEVIDPPSADVT
AHVVEMLAWEGRAADPRTRRGIDWLLAEQEPNGAWFGRWGVNYVYGTGSVLPALTAAGLP
TSHPAIRRAVAWLAAAQNPDGGWGEDLRSYDDRAWIGRGTSTASQTAWALLALLAAGERD
SETARRGVAWLVETQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPT
PGGSP
>A0A840GRP5|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. CIR18|TrEMBL
MDSVNATSREALQPGTLQPGILQSGILESSIASATQGVLDFQQADGHWVFELEADCTIPA
EYVLLRHYLAEPVDAVLEAKIANYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGD
SVDAPHMVRAREAIHARGGAIHSNVFTRFLLAMFGVVTWRAVPVLPIEIVLLPFWSPFHL
NKISYWARTTMVPLMVLAALKPLAKNPKGVGIDELFLQDPRSIGMTAKAPHQSIAWFLLF
RSLDAVLRVIEPMFPKALRKRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKD
ENFPPRAITRRGIDKLLVIKDDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLD
WLIPKQELELKGDWAVKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGATGY
DAAIDRGREWIEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISML
AQLGETEKTSKHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDHGDPM
IRKAADWLASIQNKDGGWGEDAVSYRLDYRGWEAAPSTASQTAWALLALMAAGEVDHPAV
ARGVEYLIATQNKKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRV
VGVGM
>A0A8F6CM19|squalene-hopene cyclase|EC 5.4.99.17|Methylococcus capsulatus|TrEMBL
MLREATAISNLEPPLTASYVESPLDAAIRQAKDRLLSLQHLEGYWVFELEADCTIPAEYI
LMMHFMDEIDAALQAKIANYLRGHQSADGSYPLFRGGAGDISCTVKVYYALKLAGDSIDA
PHMKKAREWILAQGGAARSNVFTRIMLAMFEQIPWRGIPFIPVEIMLLPKWFPFHLDKVS
YWSRTVMVPLFILCSHRVTARNPSRTHVRELFTVDPQKERHYFDHVKTPLGKAILALERF
GRMLEPLIPKAVRKKATQKAFDWFTARLNGVDGLGAIFPAMVNAYEALDFLGVPPDDERR
RLARESIDRLLVFQGDSVYCQPCVSPIWDTALTSLTLQEVARHTADLRLDAALSKGLKWL
ASKQIDKDAPGDWRVNRAGLEGGGWAFQFGNDYYPDVDDSAVVAHALLGSEDPSFDDNLR
RAANWIAGMQSRNGGFGAFDADNTYYYLNSIPFADHGALLDPPTADVSARCAMFLARWVN
RQPELRPVLERTIDYLRREQEADGSWFGRWGTNYIYGTWSVLLAYEAAGVPNDDPSVRRA
VAWLKSIQREDGGWGEDNFSYHDPSYRGRFHTSTAFQTGFALIALMAAGEAGSPEVQAGV
DYLLRQQRPDGFWNDECFTAPGFPRVFYLKYHGYDKFFPLWALARYRNERYALA
>A0A7W9PXH7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces echinatus|TrEMBL
MTATTDGSTGATLPPRAAAASDTTLITPEAAGVQEAAARAARRATDFLLATQDTEGWWKG
DLETNVTMDAEDLLLRQFLGILDEHTAQAAATFIRGEQRPDGTWATFHGGPGELSATVEA
YVALRLAGDAPDAPHMAKASAWIRERGGIAAARVFTRIWLALFGWWKWEDLPELPPELIY
FPTWFPLNIYNFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPANPNPPQPLAPVAS
WDGLFQRLDKVVRGYRKVAVRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVLREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALVDAGLPVDHPQ
LVRAADWMLGEEIVRPGDWAVRRPQLPPGGWAFEFHNDNYPDIDDTAEVALALRRVRHHD
PERVDHAIARAVRWNLGMQSRNGGWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAAEGLAHDPRTRRGIDWLLAEQEPDGSWFGRWGVNYIYGTGSVVPALTAAGLPGSH
PAIRRAVVWLESVQNDDGGWGEDLRSYKHVKEWSGRGASTASQTAWALMALLAAGEKDSK
AVERGVQWLAGTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFER
KLLARPRKTSPQAEGD
>A0A6P0HY63|squalene-hopene cyclase|EC 5.4.99.17|Okeania sp. SIO3H1|TrEMBL
MIEKNKVKQSILASQEYLLNLQKPEGYWWGKLESNVTITAEIVLLHKIWQTDNKRPLYQA
KLYLISQQREHGGWELFYGDGGDLSTSIEAYMALRLLGISKTDPIMLKAREFIIKLGGIS
CSRIFTKLHLALIGCYNWQGIPSIPPGIMLFPEDFPFTIYEMSSWARSSTVPLLIVFDKK
PIFSLNPTINLDELYAEGINNASFELPRQYNLTDLFLGLDTAFKFLENLNLMPLREEGLK
AAEKWILERQEVTGDWGGIIPAMLNSMLALRCLEYDVADPIVVRGFEAIDRFGIESEDGY
WVQPCVSPVWDTAWVIRSLVDSGIPPSHPAVVKAGEWLLEQQILDYGDWAVKNKLGKPGG
WAFEFINRFYPDIDDTAVVVMALDAVELPDQELKRVAIARAMEWIASMQCEPGGWAAFDV
DNDQDWLNGIPYGDLKAMIDPNTADVTARVLEMVGFCGLSMDSRRVKRAIAYLEREQEGE
GCWFGRWGVNYIYGTSGVISALAVVARESHGGFIERGATWLVGCQNSDGGWGESCRSYND
PSLKGRGKSTASQTAWALIGLLAAGEVTGNFAREAIDRGVDFLVSTQNDDGSWLESEFTG
TGFPCHFYIKYHFYPQYFPLMALGRYENLLSG
>A0A5Q0GP89|squalene-hopene cyclase|EC 5.4.99.17|Anabaena sp. YBS01|TrEMBL
MRTQDRVQVNSIAEAIAASQKYLLSLQNPTGYWWAELESNVTITAEVVLLHKIWGTDKTR
PLHKIEAYLRSQQKQHGGWELFYGDGGELSTSVEAYMALKLLGVPATDPAMIQARDFILQ
RGGISKTRIFTKFHLALIGCYNWRGLPSLPAWVMLLPNQFPVNIYEMSSWARSSTVPLLI
VFDQKPVYQVNPAITLDELYAEGVENVRYELPRSGDWTDLFLTLDEGFKLAESFNFIPFR
EEGIKAAEKWIIERQEATGDWGGIIPAMLNSMLALRVLGYATNDPIVERGLQAIDNFAIE
TADCYRVQPCVSPVWDTAWVIRALIDSGMAPDHPAIVKAGEWLLQKQIFDYGDWNVKNRQ
GQPGAWAFEFDNRFYPDVDDTAVVVMALHAAKLPHEQLKQKACDRALQWVASMQCKPGGW
AAFDIDNDQDWLNAVPYGDLKAMIDPNTADVTARVIEMLGACNLSIDSHDLERALTYLLN
EQEAEGCWFGRWGVNYIYGTSGVLCALALINPQKYQRHIQQGATWLVGCQNPDGGWGETC
FSYNDPSLKGQGDSTPSQTAWALIGLIAAGEATGNFAHDVIERGINHLVSTQQPDGSWFE
AYFTGTGFPCHFYLKYHYYQQYFPLIALGRYQAINPL
>A0A7C5FXU6|squalene-hopene cyclase|EC 5.4.99.17|Armatimonadetes bacterium|TrEMBL
MAVRAGKVSAAIGTGVEDAVSRAVAWLLDSQRPEGYWTAELEGDTILESEYIILMRFLGR
GDEVKLRKAAAYLLSKQMPNGGWAIYPGGPVDVGASVKSYFALKLTGSSADEPYMVRARE
AIREAGGIPAVNSYTKFYLAMLGQIPWEDAPAVPTELNLLPNWFYFNIYEISSWSRTFVV
PLSIIWARKPVAHVPHDQGVRELFENGDRGRVRLRARGLLNWRSFFVRVDGLIKFVERIG
FLPLRARAVRKAEQWMLEHCEHSAGLGAIFPPMVYTLIALRALGYADDSPEVCKAWDELA
GLEIEEDGTLRLMPCTSPVWDTAIVINALVEAGVPPDSPALIKSVAWILGKEVRRPGDWS
VKRPDLEPGGWYFEFENDFYPDIDDTAMVIMGLAKCTEAPGKLEAMRRGLNWLCGMQGRD
GGWASFDVDNNRSIFNAIPFADHNAMLDPSTSDITARILEMFSFVEIGQEDARVRRAIEF
LRREQEPDGSWFGRWGVNYIYGTWQAIRGLTRIGIHPSDPMIQRAACWLKSVQNEDGGWG
ESCASYDDPTVKGVGPSTASQSAWALMGLMCAGEIDSEAVRAGIDYLIRNQRADGTWDEE
WFTGAGFPKVFYLRYHLYRHSFPLMALGMYKLSAEN
>A0A4Y9PK07|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium frederickii|TrEMBL
MDSVNATSREALQQEALRPGTLQPGILESSIASATQGVLELQQADGHWVFELEADCTIPA
EYVLLRHYLAEPVDAVLEAKIANYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGD
SVDAPHMVRAREAIHARGGAIHSNVFTRFLLAMYGVVTWRAVPVLPIEIVLLPFWSPFHL
NKISYWARTTMVPLMVLAALKPRAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFLLF
RSLDAILRVIEPLFPKSLRKRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKD
ENYPPRAVTRRGIDKLLVIGEEEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLD
WLIPRQELELKGDWAVKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGATGY
DTAIARGREWIEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISML
AQLGETAKTSKHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDHKDPM
IRKAAAWLASIQNKDGGWGEDAVSYRLDYKGWEAAPSTASQTAWALLALMAAGEVDHPAV
ARGVEYLIATQNKKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRV
VGVGM
>A0A0D8B8K5|squalene-hopene cyclase|EC 5.4.99.17|Frankia torreyi|TrEMBL
MPDLELRDVDRADGTHPAPDPGRTDTLSQDAADGLRETVQRAAEHLLSLQDPHGWWKFDL
ETNPTMDAEDLLLREYLGIRTVEQTEATAKHIRSRRLDDGSWPTYFGGPGELSTTVECYI
ALRLAGDPADDEPLRRSAAWIRERGGIPATRVFTRIWLALFGWWRWEDLPVLPPEIMFLP
PRAPLSIYSFASWARQTIVPLTIVSALRPRRPAPFDLAELGADEVPDAQSPDTAQSPAAR
PPAGGRTLRDAVRRLGADRPNTAKVFFRGLDATLHRYHRHPVGPLRRHALRTAERWIIAR
QEADGCFGGIQPPAVYSIIALRLLGYDLDHPVLAAALRSLDAYTLHREDGSRMVEASQSP
IWDTALAVLALADAGIDAPADVDMTPALPTQRVATGAPGQPATVPTALERAADWLLGQEV
QHRRGDWAVAHPTVAPGGWAFEFDNDTYPDTDDTAEVVLALHRLNRLRRLRHPAGTRVDA
ALERSTTWLFALQSRDGGWGAYDSDNASTLVYQIPFADFGALTDPSSADVTAHVVELLCE
TGRIRDPRTLRGVDWLLRNQEADGSWYGRWGVNYVYGTGSVLPALQAAGLPPTHPAMRAG
AQWLLSRQNPDGGWGEDIRSYGDPAWSGRGISTPSQTAWAMLGLLAADHGGTHGNASAHS
SASAHGSASAHADALAGAARWLTEQQRPDGGWDEEMFTGTGFPGFFYLNYHGYRLVWPVM
ALGRYLHSRQHPSD
>A0A4Q6XDQ0|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia sp. UYCP14C|TrEMBL
MNDLSQTQPLDAVLPDAADAALSPAEAAVVANAPAVADASATATLAPAQDAGASALDASI
TRATDAILAAQQPDGHWVYELEADATIPAEYVLLVHYLGETPNLELEQKIARYLRRIQLP
DGGWPLFTDGAFDVSASVKAYFALKMIGDPVDAEHMVRARDAILAHGGAEHVNVFTRILL
ALFGVVSWRAVPMMPVEIMLLPMWFPFHLSKVSYWARTVIVPLLVLNAKRPLARNPRRVR
IDELFRGAPVNTGMNERAPHQHAGWFGLFRCVDTVLRAVDGLLPKATRERAVRAAVAFVD
ERLNGEDGLGAIFPAMANSVMMYDVLGYPADHPHRAIARKSLDKLLIVKDDEAYCQPCLS
PVWDTSLVAHALLETGEARAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYN
NAHYPDVDDTAVVAMAMHRSAALTQSDVDREAIARAREWVVGMQSSDGGWGAFEPENTQY
YLNNIPFSDHGALLDPPTADVSGRCLSMFAQIGELPQSSEPARRAFDYMLQEQESDGSWY
GRWGLNYIYGTWTALCSLNAAGLPHDDPRMRRAAQWLVSIQNEDGGWGEGGESYKLDYRG
YERAPSTASQTAWALLGLMAAGEVGHEAVARGIDYLQREQREHGLWDETRFTATGFPRVF
YLRYHGYRKFFPLWALARFRHLKRNGLTRVTVGM
>A0A3B1DM23|squalene-hopene cyclase|EC 5.4.99.17|hydrothermal vent metagenome|TrEMBL
MSSGDLGSRRLRFDSYQPVSPQPAATTRAAFESQKIAREVSEKLPGAIEKTTDWLLQQQH
ADGHWCAELEGDTILESEYLLLLAFLKQEQSVIATKAANYLLSQQMHEGGWAAYPGGPIE
ISGSVKAYFALKLTGHSPDAEYMLRARNAIRQAGGVEKVNSFTRFYLALLGVIQYEQCPA
VPPELILIPKWSPFNIYEMSAWSRTIIVPLSIMWAFRPSRQLAPEQGIDELFIGKAKDLP
ACMPLENDSFFSWRKFFSWGDRVFKRIDTMRIRPFRKWAIQQATDWMTERFANSDGLGAI
FPPIVWSVVALKCLGHDEDSPLIQSAMKELERLMIDDGETIRLQPCKSPVWDTALTTIAL
RDAGVPRDNPAIRQSVQWMLSKEARRKGDWAERDTKTMAGGWFFEYHNEFYPDVDDTSMV
LMALIKSLPTNSQQQWRADFLVEDWSPDALGNPSAAIVSTRNANPAEVLDDIQTLSPTLT
AIWRGARWVLAMQGSDGGWGAFDKDNNRELFTKVPFADHNAMIDPSTADLTSRVLEMFGM
LGAPPDYPAMQNGIDFCWKEQEADNCWFGRWGVNYIYGTWQTIVGLTAIGIPADDRRIQA
ASDWLLEKQQECGGWGESPLSYDDPTYRGEGSRATASQTAWALMGLIAAGKAHSEAVLHG
VQFLLTSQNKDGTWSEETFTGTGFPKVFYLKYHYYPIYFPLMALAKFTKVHEG
>A0A800BU74|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Bipolaricaulota bacterium|TrEMBL
MAGIAPPGAGSEVRNGGAHRSGSLHGRGARPGAAGVGGGAMNIRAPLRHEIGIDLTALER
TIAKAQKWLLRAQYPEGFWWGELESNVTITAEYLLLGHFLGIKDEARWRKIANYLLEQQR
EDGTWAIWFGGPGDLSTTIEAYFALKLAGVDPDRPEMERAREFILSQGGVPNARIFTKIW
LALFGQWRWEDLPVMPPELMLLPSWFPFNIYEFASWARGTIVPLLIVLALRPTVPIPESA
KLDELYPEPRQARYPIRRKPGLWGWFFWWVDWALRLLERSPSAWTWKPLRQRAIKAAERW
ILAHQEADGSWGGIQPPWVYSLIALKALGYGLDHPVMRKGLEGFERFAIEEGDTWRVQSC
VSPVWDTALSMIALLDSGLPPDHPALIKAGRWLLGKQVLHSGGDWQIKMKGTKCLPGGWP
FEFENDLYPDIDDTAVVMLALLRTELPQAEKQRALERGLQWLLAMQSRCGGWGAFDKDNT
KRFITQIPFADFGAVIDPPSVDVTAHVLELLGELGYDSSSKAVRRALSYIKREQEPDGSW
FGRWGVNYIYGTGAVLPALAALGEDM
>L7E9U0|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa TAIHU98|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
KRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVDDPIVARGLKAVDNFAIQ
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPSIIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKSVMKRAVNWMATMQCKAGGW
GAFDIDNAQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVKMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYQALI
>A0A7J5D1Q7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces triticiradicis|TrEMBL
MTATTDGSTGALPPRAASASESEHETTPEAAGTVETRDAATRAMERATDFLLARQDAEGW
WKGDLETNVTMDAEDLLLRQFLGIRDEPTTRGAALFIRGEQREDGTWASFYGGPGELSTT
IEAYVALRLAGDSPDDAHMARAAAWIRERGGIAAARVFTRIWLALFGWWKWDDLPELPPE
LIYLPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDARRPSPVRPLAP
ATSWDGFFQRLDKALHQYRRVAPRALRRAAMNTAGRWIIERQENDGCWGGIQPPAVYSVI
ALHLLGYDLEHPVMREGLASLNRFAVWRDDGARMIEACQSPVWDTCLATIALADAGVPAD
HPQLVKAVDWMLGEEIVRPGDWSVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVR
HHDPDRVENAIGRGVRWNLGMQSKDGGWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVT
AHVVEMLAVEGLTHDPRTRRGVEWLLSHQEPNGSWFGRWGVNYVYGTGSVVPALVAAGLP
GSHPAIRRAVAWLESVQNEDGGWGEDLRSYDDTAGWSGRGASTASQTGWALLALLAAGER
DSKAVERGVVWLAETQLPDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEP
FSAAEGG
>Q3JBH8|squalene-hopene cyclase|EC 5.4.99.17|Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / JCM 30415 / NCIMB 11848 / C-107)|TrEMBL
MTRALRQAPESAGAIGIAAASPATETSGQDTHPREISGAITAARDALLKLQQADGHWCFM
LEADCTIPAEYILWTHFTGELEPEIERKLAARLRAKQASHGGWPLYEGGDLDISCSVKVY
YALKLVGDDPNAPHMRRAREAILAQGGGARANVFTRLALAMFSQIPWRGVPFIPVEIMLL
PRWFPFHLSKVSYWSRTVMVPLAILYSLKAQAQNPRNVHIQELFTVPPEQERHYFPVRSR
LNKILLSVERTARLLEPLIPSMLRRRALKKAETWFTERLNGEDGLGGIFPAMVNAHESLI
LLGYSPDHPWRVQAKKALQNLVIEEKNSASCQPCLSPIWDTGLAALALQETEGGHTTAPV
IRALDWLKERQILEQSGDWQVQHPNLKGGGWAFQYNNSYYPDLDDTALVAWSMDQAATPE
RYGEAIGRACDWLCGMQSRNGGFAAFESDNTHYYLNEIPFADHGALLDPPTADVTARCIV
LLGRLNKPQYAETLQRALDYLRREQEPNGSWFGRWGTNYIYGTWSALTALEQANIDPQEG
FIRKAVEWLKQVQRLDGGWGEDNYSYFDSSLAGRYQESTPVHTAWALLALMAVGEANSEA
VKKGIAYLLQIQQEDGLWDHPAFNAPGFPRVFYLKYHGYDKFFPLWALARYRNHLNRQC
>A0A6G2M3S2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4923|TrEMBL
MTATTDGSTGAVDPRAASARRTTTESTIAADGVLAAARRAAERSVEHLLGRQDEQGWWKG
DLATNVTMDAEDLLLRQFLGIQDPATVRAAAGFIRGEQLGDGTWATFHGGPADLSTTIEA
YVALRLAGDRPEDPHMVRAAGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMF
FPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPANPNPPKRPAPARS
WDGLFQRLDKALHVYHRFAPRRLRRVAMNSAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVMRAGLESLDRFAVWREDGTRMIEACQSPVWDTCLATIALADAGVAPDHPA
LVRAADWMLAEEIVRPGDWAVRRPGLEPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPD
QARVDAAIERGVRWNVGMRSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHV
VEMLAVEGRAAHPVTRRGIEWLLAEQDPAGGWFGRWGVNYVYGTGSVVPALTAAGLPPSH
PAIRRAVEWLESVQNDDGGWGEDLRSYSEEKWIGQGASTASQTAWALLALLAAGRRDTVA
VTRGIAWLTETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFAGR
TPTREGA
>A0A3N7ZMM6|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp9142|TrEMBL
MIRRMNKPAPSSWSALDTAIARGRDALMRLQQPDGSWCFELESDATITAEYILMMHFMDR
IDDARQERMARYLRAIQRLDTHGGWDLYVDGDPDVSCSVKAYFALKAAGDSEHAPHMVRA
RDAILKLGGAARSNVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNVTIPELFVTPPDQERQYFPPARGMRRAFLALDRVVRHVEPL
LPKRLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMDVLGYPDDHPLRRDCENAL
EKLLVTRPDGSVYCQPCLSPVWDTAWSTMALEQARGAAVPETAEPAGAPDELDARIARAY
DWLAERQVNDLHGDWIENAPADTQPGGWAFQYANLYYPDIDDTAVVTAMLDRRGRTHRNA
DGSHPYAARVARALDWMRGLQSRNGGFAAFDADCDRLYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTQRADDHASLARAIDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALADED
PSQPYIARALAWLRARQHADGGWGETNDSYIDPALAGTNAGESTSNCTAWALLAQMAFGD
GESESVMRGIAFLQSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLV
GGASSVDARTVSSSNAADAALA
>A0A7K2KPW9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID6041|TrEMBL
RLDAAAARATERAAEHLLALQDAEGWWKGDLETNVTMDAEDLLLRQFLGILDAGTTRAAA
LHIRREQREDGAWATFYGGPGDLSATVEAYVALRLAGDPPEAPHMARASAWVRERGGVAS
ARVFTRIWLALFGWWRWEDLPELPPELLFLPTWFPLNIYDFGCWARQTIVPLTVVSAKRP
VRPAPFPLDELHTDPARPAPPRPLAPATGWDGLFQRLDKALHVYHRVAPRALRRTAMNQA
ARWIIERQENDGCWGGIQPPAVYSIIALHLLGYDLGHPVMRAGLDSLDRFAVWREDGSRM
VEACQSTVWDTCLATIALADAGLAPDHPALVKAADWMLDEEITRIGDWAVRRPGLPPGGG
WAFEFHNDNYPDIDDTAEVLLAFRRVRHPDPARLEAAVARGARWTLGMQSKGGAWGAFDA
DNTSALPNKLPFCDFGEVIDPPSADVTAHVVEMLAFEGLADDPRTRRGVDWLLAAQEPNG
AWFGRWGVNHVYGTGSVLPALTAAGLPASHPAIRRAVHWLASVQNEDGGWGEDLRSYDDE
AWIGRGASTASQTAWALLALLAAGERDSAPVRRGVAWLAGTQREDGSWDEPYFTGTGFPW
DFSINYHLYRLVFPLTALGRYVHGEPSPGRAR
>A0A4R4S4I2|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. KC345|TrEMBL
MTTTDVSGLTGAAAAAVEAARDHLLGLQSPEGWWKAELETNVTMDAEDLLLREFLGIRTG
GDTREAARWIRSRQRADGTWANFFGGPPDPSTTIEAYVALRLAGDPADADHMRRAAAYAR
EAGGVEGSRVFTRIWLALFGQWSWDDLPVMPPELMFLPSRVPLNVYDWACWARQTIVPLT
VLGSLRPVRALPFDLPELRGGARPAREAKGWGRAFETLDRVLHVYERRPVRPLRTAALRR
AAEWIVARQEADGCWGGIQPPWVYSLMALHELGYGLDHPVMARGIAGLDRFTIRDEKGRR
LEACQSPVWDTVLAMNALADAGLPGDAPAMARAARWVVGEEVRGPGDWAVRRPGLAPGGW
AFEFDNDVYPDTDDTAEAILALRKSGLPGAERPIGRAVGWLSGMASRDGGFAAFDADNTR
ELCTKLPFCDFGAVIDPPSADVTAHVVEALSREGLAETAVVKRAVVWLLKAQEADGSWFG
RWGANHVYGTGSAVPALIAAGVRPGKPAIRRAVAWLEEHQNGDGGWGEDLRSYDDASWIG
RGASTPSQTAWALLALLAAGERSAAVEGGVRWLVDHQRQDGNWDEEHFTGTGFPGDFYIN
YHLYRLVFPISALGRYLGGAKEVRES
>A0A7X0LM99|squalene-hopene cyclase|EC 5.4.99.17|Algisphaera agarilytica|TrEMBL
MPKFIRKFSPVIAAGFALLLTTATAPNIHALDAEHQAKARVAIDQGLDFLRSTQNADGSW
TPDPGPAVTGLIVAVMLDQPDLDATDPTIAKALEYILDRVQPDGSIRDSPDGILANYNTA
ICLSALARIDNDPEVAQVVRNAQGFLKGLQWTVGDVTPDGETITADHPYMGGAGYGNNGR
PDMSNTQLLLQGLYDSGVDCNDPAFQAALTFISRCQGIESNDFFPEGTIVNDGGVIYATS
VNKDNKHIPVSYANPEQVDEAKAGRAVSGLRGYGSITYAAFKSFLYADLERDDPRVVAAL
DWIENNYTLDQNPGMPESVKYQGLYYYYMTHARALGAYGSTYLNARGQTPTAVLHVGQRA
TAHALQQARIAQQNKGYQVTIDLETAIDGGPARDNGEINVALTESTQQIDWANALIAKLV
ELQQPDGSFVNTEKRWMETDANLVTAYSLTALMEAAN
>A0A4Z1D3Z7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces bauhiniae|TrEMBL
MTATTDGSTGATIPPRAAAASDTDSTDSTDPLAAGVPEAAERAAARATEFLLARQDSEGW
WKGDLETNVTMDAEDLLLRQFLGIRDEATTRAAALFIRGEQREDGAWATFYGGPGDLSAT
VEAYVALRLAGDAPDAPHMARASAWVRERGGIASARVFTRIWLALFGWWKWEDLPELPPE
LIWFPTWLPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPANPNPPKPFAP
LASWDGAFERLDQVVHRLRGAVPRRVRRAAMNAAARWIVERQENDGCWGGIQPPAVYSVI
ALHLMGYDLQHPVMRAGLESLDRFAVWREDGSRMIEACQSPVWDTCLAVIALADAGVPAD
HPQLLKAADWMLAEEIRRPGDWSVKRPELPPGGWAFEFHNDNYPDIDDTAEVALALRRVS
HPQPDRVDGAIARAVRWNFGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVT
AHVVEMMAAEGLAHDPRTRRGITWLLAEQEADGSWFGRWGVNYVYGTGSVVPALTAAGLP
VSHPAIRRAVHWLQQAQNDDGGWGEDLRSYKYAREWSGRGASTASQTAWALMALLAAGER
DSDAVERGVSWLAETQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDP
FDKAPLAARRGVRATAGGS
>A0A832H904|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobiales bacterium|TrEMBL
MSQSKSEPQVSTFTLGRHQLKVQVEPSLAAKVDQAISRTQNHLRSLQKTDGHWIGELIVD
TTLVCDIMLYMYWKGEVNMERQARIVKHILDRQQPDGGWRIYHGGPSEINASVKCYFALK
LAGFSPDDPVMQKAHATILRLGGIPAMNTYGKLYLALVGLFPWKYLPTIPVETILLPNWL
FFNIYELSSWTRNMFVPLSIINHFKPTRLLPPEKQLHELYPYGTEGQDFSLPWDEKWFTW
RNFFLYWDRVLKLIEACPWKPLRAKALKRAEQWIVERVSSGSDGLGAIFPSMVNTLVVFK
ILGYPDDHPLVKKNEKHLFEFEVFDEANNDYRFQPCLSPVWDTAITSVALATSGVPKNDP
QLKKAADWLISKEVRIKGDWFIKNPYPGEPSGWAFEYHNQYYPDVDDTVKVLLALRLIEA
SDEKLKEAIIRRALPWAASFQCKNGGFAAFDKDVTKKWLDHVPFADHKAILDPPCSDITA
RVLECFGKYGYTKKEPFIRKAIAYMRSTQEEDGSWYGRWGVNYIYGTWQGLRGLYYIGED
MNQDWIVRARDWLESCQNADGGWGETCASYDDPRLKGQGHSTPAQTAWALMGLLAFEDPA
RPSIQRAVGYLAATQNEAGDWTEDYITGTGFPCVFYLKYDLYRTNWPMIALSEFRQLLKA
KALPQAA
>A0A7X1IIJ7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. TYQ1024|TrEMBL
MTATTDGAGALLPRAAEAGHSVTAVTEVKEEAAGGAPAAVRAAAERATARATEYLLSHQN
EQGWWKGDLETNVTMDAEDLLLREFLGTRDDRTTRAAARWIRSQQRPDGTWATFHGGPGE
LSATVEAYVALRLAGDAPDEPHMAAASAWVRERGGIAATRVFTRIWLALFGWWKWEDLPE
MPPEIMFLPKWMPLNIYDFACWARQTIVPLTVVGAHRPVRPAPFALDELHTDPRRPNPPR
PPAPAASWDGFFQRLDKALHAYRRVAVRPLRRAALNAAARWIVERQENDGCWGGIQPPAV
YSVIALHLLGYDLDHPVLRAGLESLDRFAVWHEDADGEPVRMIEACQSPVWDTCLATIAL
ADAGLAPDHPALVKAADWMLDEQVLRPGDWSVRRPRLEPGAWAFEFHNDNYPDVDDTAEV
VLALLRVRHPDPARVQEAVRRAMRWTVGMRSRNGAWAAFDVDNTSPFPNRLPFCDFGEVI
DPPSADVTAHVVEALAVLGKQHDPRARGGIEWLLAEQEECGAWFGRWGVNYVYGTGAVVP
ALVAAGLPGSHPALRRAVAWLESVQNADGGWGEDLRSYRDADWMGRGESTASQTAWALLA
LLAAGERDSPAVERGVAWLAGTQRPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALG
RYLHGEPFAAREV
>A0A3L7TC74|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MAFIVFNSFNTTSAMERIPVPVAFKQKKHSTFNPVAGSNYNLLDKALAAVINGRNFLIQH
QQKDGHWVAELQGDTILESEFVLLRAFLGKENDEICQKCARYIQSQCRAEGGWSNFPGGP
FDLSVSTKAYFALKLTGVSTQLPWMKLAREKILQAGGAENCNSFSRFYFALLGEYSYQNC
PEVPPELLLLPSWFPVSIYSMSSWTRTILVPLSIFSAIKPSIKLPQEKGIRELFIADPWQ
AKWPSAPSKELFSWRNFFLLADLAIKKIAPRIPFLRNYAVSKAAHWMREHFQYSDGVGAI
FPPMIYTVVALKCLGVQESSPEMQWAMKQLLDLMIEENGSIRLQPCVSPVWDTALATIAV
ADAGQPEDDLKLKKAVDWLLKKEVSGKIDCSTNHPDMKPAGWFFEYNNQFYPDIDDTAMV
IIAMVKTNSHHRPECIAAIERSVRWIFLMQNRDGGWGAFDKNIDQEFLTKVPFADHNAML
DPTCPDISARVLEALGELGYNANEIHIQKAIEYIRSSQEPWGAWVGRWGVNYIYGTWQVL
LGLKAIGFDMGDPMVARAVQWLKGCQHEDGSWGETCATYDDPSLAGQGDATPSQTAWAVL
GLIAAGEEHSDSVRNGIGYLVNTQNSEGDWTENFFTGTGFPKVFYLKYHYYRVYFPLMAL
SRYCRLLGYAFEQNTY
>A0A3L7T9D4|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MREVPHDSIRRPHPERRPLSNAEIEQHLERAVVALKSLQKPDGHWCGELEGDSILQSEYL
LMKWILGQERLPMGDGRPAQTLLRIVDYLRGQQRADGGWGAYPGSPSDLSASVKAYFCLK
LFGDSPEAAHMKKARAIVRHLGGAERCNSFTKFYLAGLGQISWNAVPAIAPEIVFLPKSF
YFHLDKVSAWSRVMILPLTIVSTKRHTRELPVTLGIGELFVDHEARHQLSMRDGAPPFWT
NFFARVDRALKWLHGRGGTPWRHAAIVRAFDWLEAHAGEGGIGAIFPSMVYWQVVLHALG
YERSHPLVVRAERELDRMLVEIGAGADAPMRVQPCLSPVWDTGIALYALADCGFDNFDPK
VARAAEWLVAKECRVAGDWMANLDAPAAPSGWFFQYDNAQFPDCDDTAMVVMALMRAGGD
ANRAAAGRGARWLLAMQNDDGGWAAFDRTSDRRILEYVPFADHNAMQDPSCPDITGRVLE
CFAWHGLTKDHAAVAAGIAFIRGRQEPEGCFFGRWGVNYIYGTWQAVIGPIRCGVARDED
WILRAGRWMKSIQKPDGSFGESAESYENPALKGQGPSTASQTAWAAMVLQEIYGPDDEDL
RRAISWLCHTQLDRAAANDPISNPDGDPAGSWRETEFTGTGFPRIFYLRYHLYRLYFPTM
AIGRYLAALGRGEQGRRLVATGERAALGL
>A0A8F8WSN0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces anulatus|TrEMBL
MTATTDGSTGAANLSGAPADPTDTTTAADDVTVAARRAAERSVEHLLGRQDEQGWWKGDL
ATNVTMDAEDLLLRQFLSIQDPETTRAAALFIRGEQLGDGTWNTFYGGPGDLSATIEAYV
ALRLAGDRPDEPHMARASGWVREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFFP
KWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPDHPNPARKLAPPASWD
GIFQRLDKGLHLYHKVAPRPLRRIAMNLAARWIIERQENDGCWGGIQPPAVYSVIALHLL
GYDLDHPVMKAGLASLDRFAVRREDGARMVEACQSPVWDTCLATIALADAGLRPDHPALV
KAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDPA
RMQAAIDRGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVVE
MLAVEGLAHHPRTREGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALIAAGLPAGHPA
IRRAVGWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDTRPVA
RGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFAGRAD
AAEGA
>A0A8B2QB23|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cepacia|TrEMBL
MIRRMTRSTLSPWSALDIAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDLRQERMARYLRANQRLDTHGGWALYVDGDPDVSCSVKAYFALKAAGDSEHAPHMVRA
RDAILKLGGAARSNVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNVSIRELFVTPPDEERRYFPPARGMRKLFLALDRTVRHVEPL
LPKGLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMQVLGYPDDHPLRRDCENAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVAVPEDGEPDDARRALDARIARAY
DWLAERQVNDLRGDWIENAPADVQPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRTHRNA
DGTNPYAPRVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRADERASLARCIEYVKRTQQPDGSWWGRWGTNYIYGTWSVLAGLALAGED
KSQPYIARAIEWLRSRQHADGGWGETNDSYIDPKLGGTNGGESTSNFTAWALLAQMAFGD
CESDSVKRGIAYLQSVQQEDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GAAAAAPAAVDAADTAVA
>A0A6N8ENI9|squalene-hopene cyclase|EC 5.4.99.17|Bombella sp. ESL0378|TrEMBL
MSATLSRHKIDATAVEQAVKASHTALGKRQKEDGHWVFELEADATIPAEYVLLRHFLDRI
DEPLEQKIGVYLRRIQGVHGGWSLYTDGKFDLSASVKAYFALKMIGDDINAPHMRRARAA
ILQHGGAERSNVFTRIQLALYGEVPWHAVPVMPIELMLLPRKAFFSVWNMSYWSRTVIAS
LLILVTRKPLAINPRGVHVQELFKTPPAQVKDWIRGPYRSIWGRLFTYLDKALRPVVPHI
PRSIHAKAIRTTIQFVEERLSAGGLGAIYPSMANVVMMYRVMGVPDDDPRAVEAWQAVQD
LLVVKDDEAYCQPCVSPVWDTGLSGLAMMEAATGPKAVQNAETMAALEKAASWLRERQIL
DVKGDWAINTPHLRPGGWAFQYKNDYYPDVDDTAVVGMLLHRMAPEKNAPAIERAREWII
GMQSSNGGWGAFDIDNDLEALNHIPFSDHGALLDPPTVDVSARCISFLAQLGHPEDKDVI
RKGIDYIRKEQEASGSWFGRWGTNYIYGTWSVLCALNIAGVPHDDPMIQRAVAWLESVQN
DDGGWGEDCASYEGAPQGVYKESLPTQTAWATLGLMAVGRQESEAVQRGMAYLTQAQDEA
GEWHEAPYNAVGFPKVFYLRYHGYKQFFPLMALSRYRNLASSNSGRVEYGF
>A0A535Z442|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
VALRVLGVDSSRDELRRALRFIRMQGGVAEARVFTKIWLALFGQYPWDGIPSMPPELVQL
PPRVPLNLYDFACWARGTIAPLLIVISRRPLRPLGFDVSELVAPETAHRLRTVPGSGAFW
WLDHALKLYDHSHWQPGRRRSRRRLVEWICARQEADGSWGGIQPPWVYSLIALNLEGMSL
EHPVMARGLEGLRRFTLDDGTHGWRLQACMSPVWDTAWSLIALRRAGLGRDHPAIRTAVD
WLLGEQITSGGDWQVKVPMDSCGGWAFEFDNDTYPDIDDTAVVVLALLEAGDPDRVAPAV
KQAVRWCRAMRSTGGTWGAFDKDNTRALVYSLPFADFGAMLDPPSEDVTAHVVEMLAATG
STATDPHVAPGIAYLRREQRPWGSWFGRWGVNHIYGTWCVVSALRALHSCGTAVERATTW
LARAQNPDGGWGESCLSYDDESFAGVGESTASQTAWAVHTLQLAGLAANPAAAHGLAWLR
ERQRGGTWDETEHTGTGFPGDFYINYHLYRHVFPTLALAGESASVPGDAATLQVASTDGE
LAPAARQHTYA
>A0A385T195|squalene-hopene cyclase|EC 5.4.99.17|Brevibacillus laterosporus|TrEMBL
MKEKIELEIKRIIHLLQKAQSADGAWRYCSESGPLTDAYMIILLRTLMIDDEELIRSLAD
RITIRQEKNGAWKLFHDEEEGNLSATIEAYYALLFSGHSQKTDEHMQLAKKFILTKGGIS
EASMLTKILLALTGQYPWQGYFQIPVEIILLPHWFPINFFDFVGYARVHIAPILVVADRK
FVMKTKRTPDISDLRKNDLPTALGNHPYLTNQRSHEYRALLNTILDGFKNLPYLPSQIHN
MALRQAERFILERIEPDGTLYSYFTSTFLMIFALLSLGYSANHPVIARAISGLKAMTCLT
NGHFHIQIATSTVWNTALLAHAMQATGVSASDPTVQNAGRYLLSRQHHKYGDWMMKNLFV
LPGGWAFSNINTINPDVDDTTAALKAISKLRETDPTFHHSWDRGLNWLLSMQNADGGWPA
FEKNTDKRILNWLPFNAADAVSTDPSTADLTGRTLEFLGNSVGFTIGHPQIQRGVEWLLS
NQEANGSWYGRWGISYVYGTWAAATGLIAVGVSSEHPAIQKAVKWLLKIQNEDGGWGESC
KSDIVKTYVSLGVSTPSQTAWGVDALISVFQKPIPAIERGIQFLIDSEKNQDWTLSYPTG
AGLPGGFYFHYHSYRYIWPLLALGNYKKKY
>A0A552FG75|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa Ma_QC_Ch_20071001_S25D|TrEMBL
MQIQDKITEIASKTAKAIELSQNYLLSTQYSDGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDLALEKAREFI
LAKGGISKTRIFTKMHLALIDCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKAVDNFAIE
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKSVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRHQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A5C7VU39|squalene-hopene cyclase|EC 5.4.99.17|Nitrosomonas oligotropha|TrEMBL
MDGLQRVANLSQQQSDFTVNGETPESDTATTLNQDGINTAELETKFDQARTAMLALQNPD
GHWCFPLEADCTIPAEYILMMHFMDEIDVILENKIARFIRDKQDMTHGGWPLYYGGAFDI
SCTIKSYYALKLVGDSTDAPHMVRAREAIMERGGAAKANVFTRLLLAMYDQIPWHGVPVV
PSELVLLPSWFPFHISKVSYWSRTVMIPLSILCTMKARAINPRKVNIRELFIVPPEEEKN
YFPRADTVLKRAFMLVERILSRVEPKLPQSIRQYSIRKAERWTLERLNGECGIGAIFPAM
VNAHEALTLLGYAYDHPNRVQCRNALRGLLVDEGERIWCQPCTSPVWDTVLTSLALQEDP
TTGQEPVLKALDWLVEQQVLDEPGDWRDKRPELLGGGWAFQYANPHYPDLDDTAAVAWAL
DQGGAERHHKSLERAANWLAGMQSRNGGFAAFDIDNTHHYLNEIPFADHGALIDPPTSDV
TARCVGLLGKFGRHQLEVWRGISFLLREQEQDGSWFGRWGTNYIYGTWSVLEAFQLAKFD
MQHHSVRRAVKWLESVQRADGGWGETNDSYLDKQLAGRFPETSTAFQTAWAVLGLMAAGE
VNSESVRRGINYLLRNQSSDHLWEDPWFTAPGFPRVFYLRYHGYSKFFPIWALARYRALT
RTVAACV
>A0A7W9U0W6|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia bannensis|TrEMBL
MNDLSQAMPADDPAHARAAALAFDGDAPHGAASAEELAHDASLAAGLDDAVARATDAILA
DQHADGHWVYELEADATIPAEYVLLVHYLGEQANLELESKIARYLRRIQLPGGGWPLFTD
GDMDVSASIKAYFALKMIGDAEDAQHMVRAREAILAAGGAEKANVFTRILLALFGVVTWY
AVPMMPVEIMLLPKWFPFHLSKVSYWARTVIVPLLVLNAKRPVAKNPRGVRIDELFRSAP
VSTGLNERAPHQSPAWFGLFRAVDGVLRVADPLFPSYLRQRAIDAAVAFVDERLNGEDGL
GAIFPAMANAVMMYDVLGYPADHPHRAIARQSIEKLVTIHADEAYVQPCLSPIWDTSLAA
HALIETGDARARAAARRGLEWLLPLQILDVRGDWISRRPDVRPGGWAFQYANPHYPDVDD
TAVVVAAMDRIDKLDKTSDFDEAMARAREWVVGMQSSNGGWGAFEPENTHEYLNNIPFSD
HGALLDPPTADVSGRCLSMLAQLGELPVASEPARRAYHYILAEQEADGSWYGRWGMNYIY
GTWTALCALNAAGLEHHDSRMRRAAQWLIAIQNDDGGWGEDGTSYKLDYRGYERAASTAS
QTAWALLGLMAVGEVNHPAVARGIAWLQQTQREHGLWDETRFTATGFPRVFYLRYHGYRK
FFPLWALARYRNLKREGTTLVKAGL
>A0A6B2RZI3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID10853|TrEMBL
MTATTDGSPGAMEPRAAAATGPAETIEPSGNTENTDTILAGRDPVRDAAEQAAERSVEYL
LKAQDAQGWWKGDLETNVTMDAEDLLLRQFLGIQDERTTRAAGQFIRGEQRADGTWATFF
EGPGELSTTIEAYVALRLAGDEPDAPHMALASDWIRAHGGVAESRVFTRIWLALFGWWKW
DDLPELPPEMIFLPKWFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHADPAD
PNPAKRPAPLVSWDGAFQHLDKALHLYHKVAPRRLRKTAMNAAARWIIERQENDGCWGGI
QPPAVYSVIALHLLGYDIDHPVMRAGLESLDRFAIWREDGARMIEACQSPVWDTCLATIA
LADAGLSPDHPALVRAAEWMLAEEIDRPGDWSVRRPGLAPGGWAFEFHNDNYPDIDDTAE
VALALRRVQVPDRARLEGAIARGVRWNLGMQSKDGGWGAFDADNTSPFPNRLPFCDFGEV
IDPPSADVTGHVVEMLAIEGKAQDPRTRRGIEWLLAEQEATGAWFGRWGVNYIYGTGSVV
PALTAAGMPGSHPAIRRAVSWLESVQNEDGGWGEDLRSYKEEAWIGHGASTPSQTAWALL
ALLAAGERENKAVERGVSWLAGTQRQDGAWDEPYFTGTGFPWDFSINYNLYRQVFPLTAL
GRYIHGEPFAGTRQGS
>A0A6G3UVV5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID9124|TrEMBL
MTATTDGSTGAVDPRAASASRPTIESTIAADGVQAAARRAAERSVEHLLGRQDEQGWWKG
DLATNVTMDAEDLLLRQFLGIQDPATLRAAAGFIRGEQLGDGTWATFHGGPADLSTTIEA
YVALRLAGDRPEDPHMARAAGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMF
FPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPDRPNPPKRPAPAAS
WDGVFQRLDKALHVYHRFAPRGLRRVAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVMRAGLESLDRFAVWREDGTRMIEACQSPVWDTCLATIALADAGVAPDHPA
LVKAADWMLAEEIVRPGDWAVRRPRLEPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPD
QARVDAAIERGVRWNVGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHV
VEMLAVEGRAADPVTRRGIEWLLSEQDAGGGWFGRWGVNYVYGTGSVVPALIAAGLSPAH
PSIRRAVEWLESVQNDDGGWGEDLRSYAEEKWIGQGASTASQTAWALLALLAAGRRDTVA
VTRGIAWLTETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFAGR
APMREGA
>A0A6M0B9G8|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO3I6|TrEMBL
MQTQDRIVHSGVTEAIANSQSYLLAQQYPDGYWWAELESNVTITAEIILLHKIWGTDKQR
PLHKAEAYLRSQQRKHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDSALVRARDFILR
RGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPEWFPFTIYEMSSWARGSTVPLLI
VFDQKPVFDSQPRINLDELYTEGADHAKFELPRNSDWTDLFVLLDDGFKLAEDLNLVPFR
KEGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPVVQRGLEAIDRFAIE
TPDSYRVQACVSPVWDTAWVLRAMVESGLEPDHPALVRGGEWLLQQQILDYGDWVVKNPQ
GKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLKQAAIARGLAWIASMQCNQGGW
AAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEMLGSCNLSIESQQLEKAIAFLIQ
EQEADGSWFGRWGVNYIYGTSSALSALSKIAPHTHQRSIERGAAWLVKCQNLNGGWGETC
LSYDDPSLKGLGISTASQTAWALIGLMAAGEATGNWARDAIEMGVNYLVSTQQPDGSWDE
TEFTGTGFPSHFYLKYHFYQQYFPLLALGRYQMSVSS
>A0A7D5S417|squalene-hopene cyclase|EC 5.4.99.17|Defluviicoccus sp|TrEMBL
MRDTFDDFGRGTAVPCDEVLDMTIDEAAGWLRNRQAHDGHWVFELEADATIPSEYILLNH
FLDEINDPLEQKIAVYLRRTQGHDGGWPLYRGGEFDLSATVKTYYALKLVGDDPDAPHMR
RAREAILAAGGAARSSVFVRIQLALFGQVPWRAVPWIRPEAMLMPKWAPFHIEKVSYWSR
TVMVPLFVVAALKPQARNPRGIDIRELFXRSAGRRGGVPAQPDRRTGWGXVFLAIDRIGR
KVEPLFSRRLEKISIQRAVTFVKERLNGEDGLGGIFPAMVYALMMFDALGYPRDHPDLVT
IRKSIDKLVVFRETEAYLQPCLSPVWDTGLALHALLEAGLSNEDAAVATGCRWLVDRQVL
DVRGEWASNRPDVRPGGWPFQYRNDHYPDVDDTAVIVMALNRASETDYDGSVARACEWVL
GMQSRNGGWGAFDADNEHYALNSIPFADHGALLDPPTADVSARCLGMLMQLGHSRSHPAV
QRALAYLKGEQETDGSWFGRWGTNYIYGTWSVLCALNAVGEDPESPHIRKAVAFLKSRQR
EDGGWGEDCASYWPERRQEVKASTPSQTAWALLGLMAAGEVDSPEVKRGIEYLLSSPRDG
GQWQEELYNAVGFPRVFYLKYYGYSAYFPLWALSRYRNLSRGNRKTTAYGI
>A0A3S8XJY1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. KPB2|TrEMBL
MTATTDGSTGAALRPLAASASDTDSTIPASAAGVPEAAARATRRATDFLLSKQDAQGWWK
GDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDSPDAPHMARASEWIRSRGGIAASRVFTRIWLALFGWWKWDDLPELPPELI
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFSLDELHTDPARPNPPRPLAPAA
SWDGAFQRIDKALHAYRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPEDHP
QLVKASDWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHH
DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAVEGLAHDPRTRRGIQWLLDAQEADGSWFGRWGVNYVYGTGSVIPALTAAGLPTS
HPAIRRAVRWLESVQNEDGGWGEDLRSYRYVREWSGRGASTASQTGWALMALLAAGERES
KAVERGVAWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFA
KKSPAAEAPTASVVAEVKGS
>A0A7V0MM42|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MKTEIAYIHKIDAKHKVAQKSGKEESLSERLISSINRTTNYYLQCQHPEGYWWFELESNV
TITAEYLMLLKFLGIENPEREQKIVTHLLRKQRSDGTWAIYYDGPGEISATVEAYFALKL
AGYPEDSEEMTSARDFILKSGGIENCRIFTKIFLALFGNYSWERIPPFPVELILFPDWFP
FSIYAFSSWTRASLVPISILLHLRPVKTIEGARVDELYVSSPNGRKKPSNCMNFLIFSRH
IGKLLFKAPFIPLRNKALKKAEEWIVDHQEKSGDWAGIQPAMVNSLLALFSLGYPLDHPV
IQKGLEALETFLIDKGDEVVLQSCISPVWDTALNCIALVEAGIPPKYPAIQLAAEWLLKQ
QIFRGGDWQVKRPDLEPGGWAFEFHNDHYPDVDDSAVVLMALQRAVGDNPSAKCAIERGI
NWVLGMQSSDGGWGAFDVDNNKEYLNRIPFADLEAMIDPSTADLTGRVLQMMGYYGYDKD
HPVAKKAIRFLRKIQEPDGSWWGRWGVNYIYGTWSVLSGLESIKEDFSQPWIQKAVQWLK
NCQNPDGGWGETCESYKDPSLSGHGPSTASQTAWALLGLMAAGEWESPEISRGIQYLLKN
QQPDGTWEEEYFTGTGFPKYFMLRYHNYRNCFPLMALGRYYGWLQDQLRLPGKTSLQMS
>A0A7V5K5J1|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MRANDVLTIATAPVEPDIPSREELRRAVERAQARFLAEQAPEGWWWYELESNVTITAEYL
MLFRFLGIADPDKERKMARYILGQQREDGTWGIYYGAPGCVSTTTEAYFALKMAGVSPSE
PSMNKARQFILDSGGIEATRVFTRIFLALFGQYPWKKLPSLPVEIILLPGWSPFSVYDFS
SWARATLIPISILLDRKPLVELPKGQAVEELCGAGRPPRPRPMGWLTWERLFHIIDQLLK
HSEELPIRPFRKRAVRGVEDWILKHQEPTGDWGGIQPAMVNSLLALKTLGYSLEHPAVRK
GLEALERFSIEEPEQLRLQSCISPVWDTPLTCIALLDSGLPKDHPAFTRATEWLLARQIL
KEGDWKVKNPGLAPGGWAFEFQNDWYPDVDDSAVVLMALKRMWMDGEPAQDDRIQKGMAW
VLGMQSRNGGWGAFDTNNDKEILNRIPWADLEANLDPPTADLTGRVLEFMGHYGFGAEHP
AARAGIRFLKRVQEPDGCWWGRWGVNYIYGTWCVLCGLGAIGEDMNQPYVRRAVRWLKDH
QNWDGGWGETCDTYRRPELRGSGPSTPSQTAWALMGLMAAGEISSQEVIRGIRYLLAQQE
EDGTWPEAYFTGTGFPKYFMIRYHNYRNCFPLMALGRYQRGLALG
>A0A7L9UB59|squalene-hopene cyclase|EC 5.4.99.17|Massilia sp. LPB0304|TrEMBL
MEAGLAGAARLDAQPTRLASAIDAALGAVLDDQRPDGHWVYELEADATIPAEYVLMVHFL
GEPPDAVLEAKIGRHLRRVQGAHGGWPLFHGGAYDPSASVKAYFALKMIGDPVDAPHMAR
ARAAILAHGGAEQSNVFTRFLLALYGIVPWDAVPAMPVEIALLPEWFPFHLTKVSYWTRT
VLTPLLVLGALKPRARNPRAVGIDELFLAPPGQLRVTARAPHQSRLWFAFFRTVERHVRR
LEPRIPARLRRRAIERASAFVRARLNGEHGLGAIFPAMVNAVQMLDALGLERNTGEYAGA
RRAIDRLLVDRGEEAYCQPCFSPVWDTALMCHALLETGTLQAIDAALRGLEWLRPLQILD
LHGDWSLNRPGLRPGGWAFQYANAHYPDVDDTAVVAMAMHRADRVLGEPRFADAVERAHE
WVLGMQSRDGGWGAFDPDNTCRYLNNIPFADHGALLDPPTADVSARCLSMLAQLDPQACR
RRGSPAARALDWLLCAQEPHGAWYGRWGINYVYGVWSALCALNAAGMGMEARPVARAVDW
LHAVQNPDGGWGEDGSSYRLDYAGHEPFQSLPSQTAWALLGLMAAGAVDSPAVARGIDWL
LEQQRADGLWDEEHHTATGFERVFYLRYHGYARYFPLWALARYRKLRASGSKRVGFGM
>A0A534R5Y0|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MSASEGQLTLVGRDAEGLPARAAQAISRATQYLLVTQHARGYWHAPLEANVTMEAEYIFF
NRLLGRTKPDLDRRMAERLVALQQAEGSWPIYAGGPGNLSTTIEAYFALRLAGHAPSEPA
LVRARDFILAEGGLARAGVFTRIWLAYFGQFPWTGVPAMPVELVLLPPWFPINIYAMSSW
ARGTVVPLTLLMAHRPYAHVGAEAAVPELWLRPPTPADLAFARSREFATVRNLFLAVDRA
LNVVGRSPWKPLRRRAVARAIEWILRHQDKNGQWGGIQPAMLNSVLALHAVGFAPDHPAM
VSGVHGVDDFLVECEGTLMYQPCVSPNWDTALAARALLDSGMEPTHPALERAGEWLVANQ
IFRPGDWAVQRPSLEPGGWAFEFANDWYPDVDDSAVILTVLRELPLAATPDGKRAIAYGL
NWTIGMQSRNGGYGAFDADNTAAFLNRIPFADMEAMIDPPTADLTGRLLQLMGGEGYGLD
FGRARRAVEFLRRTQRPDGSWWGRWGVNFIYGTWCALTGLAAIGEDLRAPYIRRAVEWLI
ARQNADGGWGETVASYDDETLAGRGESTPSQTAWALIGILAADGPASAAVERGINYLVRT
QGADGTWTERPFTGTGFPRHFYLRYHLYRHYFPLMALGHYRAGVAARSGEEG
>A0A7K2CV80|squalene-hopene cyclase|EC 5.4.99.17|Acidimicrobiia bacterium|TrEMBL
MGVEQSLAKATERLLSLQDTQGWWKDELETNVSIEAEDLFLREFLGIADPEVTRQTANWI
RHNQRADGTWATFYQGPADLSVTVEAYWALRYAGDPVDADHMTKAAAYIRGEGGLERSRV
FTRIWMALFDLWRWEDLPALPPEVIFLPKRVPLNIYDFACWARQTLVALTVVGAHRPVRS
MGLNLDEIRTGAIPPERELAPLGSPARRFQRLDQVLHLYENRPQRRVREWALSRAEQWII
ARQESDGCWGGIQPPWVYSLLALYVRGYSLHHPILAQGLDGFDAWTIVEDDMRRLECCQS
PVWDTCLALLALADAGMDPEDPQMMAGARWLIDQEVQIVGDWAEQRPHLAPGGWAFEFEN
NYYPDLDDTAEVALALRRIHHPDAKQVNGALDRAVIWAQGMQCSDGGWAAFDADNCSPLV
AELPFCDFGEVIDPPSADVTAHVVEMLAELDADDKGFPIDRGALARGIQWLTDEQERDGS
WYGRWGANYIYGTGAVVPALISAGVPADDDRVVRACRWLESVQNHDGGWGEDMRSYVDDN
WRGRGESTPSQTAWALLALIAAGRADEEAARKGVAWLLDNQRDDGDWDEPWYTGTGFSGD
FYIRYHLYRLVFPLMALGRWVRATTGEG
>A0A534QH79|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MSTSEGRLTLVGGSTGEGLPVRVPQAIARASQYLFATQHARGYWHAPLEANATMEAEYVF
FNRVLGRERPDVERRLAERLLGLQQADGSWPIYYNGPGGPSATIEAYFALKLIGMNGTEP
ALARARDFIRGQGGLARAGVFTRIWLAYFGQFPWAGVPSLPVELVLLPPWFPLNIYAMSS
WARGTVVPLTLLMAHRPAVRIEPDAGVSELWLGPPTREELAFARSPELVTMRNFFLAVDR
ALKSLAPFSWRGLRRRAVARAIEWILRHQDTNGQWGGIQPAMVNAVLALHAVGFAADHPA
MMSGIQGVEDFLVECEGTLMYQPCVSPNWDTALAARALLDAGLDAAHPALGRAADWLVAN
QIFRRGDWSVLNPRLEPGGWAFEFANDWYPDVDDSAVILTVLDALPVARTAEGKRAIAYG
LNWTLGMQSRDGGWAAFDTDNTAAFLNRIPFADMEAMIDPPTEDLTGRLLHLMGTVGYTL
DFGRARRAVEFLRRTQRSDGSWWGRWGVNFVYGTWCALAGLERIGEDMRAPWVRRAVEWL
TARQNPDGGWGETVASYDDEALAGRGESTPSQTAWALLGLLAADGPSSAAVERGVDWLLR
TQGPDGTWEERAFTGTGFPRHFYLRYHLYRHYFPLMALGQYRARLAARNEG
>A0A7D7QI00|squalene-hopene cyclase|EC 5.4.99.17|Nostoc edaphicum CCNP1411|TrEMBL
MQTQDRVKVNQVADAIAASQEYLLSIQNSAGYWWAELESNVTITAEAVLLHKIWGTDQTR
PLHKVEAYLRQEQREHGGWELYYGDGGELSTSVEAYMALRLLGVPANDPAMIRAQAFILQ
RGGISKTRIFTKLHLALIGCYNWRGIPSLPPWIMLLPKAFPVNIYEMSSWARSSTVPLLI
VCDRKPVFITDPTINLDELYAEGVDRVRWELPQSGDWTDLFLTLDQGFKLAESLNLVPFR
EEGIKAAEKWILERQEATGDWGGIIPAMLNSMLALRCLDYDRSDPIVERGLQAIDNFAIE
TEDSYRVQPCVSPVWDTAWAMRALIESGFAPDHPAVVQAGEWLLQKQILDYGDWAVKNRQ
GKPGAWAFEFDNRFYPDVDDSAVVVMALHLAKLPNEKIKQAAIARALNWIASMQCKPGGW
AAFDLDNDQDWLNSIPYGDLKAMIDPNTADVTARVLEMLGACDLSIDSDSLERSLTYLLR
EQETEGCWFGRWGVNYIYGTSGVLSALALIDPQRHKLSIERGAAWLVGCQNPDGGWGETC
RSYDDPSLKGKGNSTASQTAWALIGLIAAGEATGKLALEVIERGISYLVATQKPDGTWFE
ADFTGTGFPCHFYLKYHLYQQYFPLIALGRYQALTRE
>A0A7Z2G9S9|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia acidiphila|TrEMBL
MKNFTPPFTASAAAMAALDASIVRGREALVRQQDADGSWCFELESDATITAEYILMMHFM
GKIDVVRQEKMARYLRDIQRLQTHGAWDLYVDGAPDVSCSVKAYFALKAAGDPANAPHMV
RAREAILKLGGAAKSNVFTRILLATFGQVPWRATPFMPIEFVLFPKWVPISMYKVAYWAR
TTMVPLLALCSLKARAANPHDVSIAELFVTPPEEEREYFARGKGIRRFFLAADRALRHIE
PLLPRALRQRAMKHAEAWCAERMNGEDGMGGIFPPIVYSYQMMQVLGYPEDHPLRRDCEN
ALEKLLVERPDGSVYCQPCLSPVWDTAWSTMALEQARTVVSADPASATVTDQELQQRIAR
AYDWLAERQVDDVRGDWIENAQPDTPVGGWAFQYENPYYPDIDDTAVVVAMLHRRGRGEA
RKTGVDPYAARVTRALDWMRGLQSRNGGFAAFDADCDRLYLNAIPFADHGALLDPPTEDV
SGRVLLCFGVTGRTEDKAARARAIEYVKATQQADGSWWGRWGTNYIYGTWSVLAGLALAG
EDPRQPYIARALAWLRARQHADGGWGETNDSYIDPRLAGTNGGESTSNFTAWALLAQMAF
GDWESESVRRGVAYLLSVQQDDGFWWHRSHNAPGFPRIYYLKYHGYTAYFPLWALSRYRR
LAGNAVQVREVEEAALA
>A0A5C4JAH2|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura soli|TrEMBL
MCGRGAPELTTTNDPFRGAWGVVPPQQDVFGLTGAAAAAVGAARDHLLGLQSPDGWWKGE
LETNVTMDAEDLLLRQFLGIRSERETAEAARWVRSQQREDGTWANFHGGPPELSTTVEAY
VALRLAGDPVDADHMRRAAKYARDAGGIEATRVFTRIWLALFGQWSWDDLPVMPPELMYL
PKRVPLNVYDWACWARQTIVPLTVLGSLRPVRALPFDLPELRSGVRPAKDEKGWGRFFNG
LDRVLHVYEKRPVRPLRRAAMRRAADWIVARQEADGCWGGIQPPWVYSLMALHELGYGLD
HPVIRRGLDGLERFTIRDEKGRRLEACQSPVWDTVLAMNALGDAGMPPSDPALRRAAAWV
VGEEVRGPGDWSVRRPGLAPGGWAFEFDNDVYPDTDDTAEVILALRKVDLPEAEAPIGRA
VRWLEGMASRDGGYGAFDADNTQDLCNKLPFCDFGAVIDPPSADVTAHVVEALCGEGLAE
SPVVKRAVVWLLKAQEADGSWFGRWGANHVYGTGSVVPALVAAGVGRGRPAIRRAVAWLE
RHQNDDGGWGEDLRSYDDPAWIGRGESTASQTAWALLALLAAGERSQAVDAGVRWLVDNQ
RPDGTWDEEQYTGTGFPGDFYINYHLYRLVFPISALGRYLQKEVRTS
>T2AZJ8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGCGPDNQAVTRAIGYLKRGQEVNGSWYGRWG
>T2AYC9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDRYSEAIARGAEWIIGMQSGNGGWGALDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGCGPDNQAVARAIGYLKRGQEVNGSWFGRWG
>T2AXT5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGS
>T2B011|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLAMHAVLEANSEPDKTVMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGRWG
>A0A0E1S6N7|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia pseudomallei 305|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>T2AZH5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVAVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGRWG
>T2AZI4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIFMEKAANWLVKRQILDVIGDWGANVHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDCYSEAIARGAEWIIGMQSGNGGWGAFDVNNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGLDNQAVARAIGYLKRGQEVNGSWYGSWG
>T2AZM6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
VWDTGLAMHAVLEANSVPDKVIMEKAANWLVKRQIPDVIGDWGANVHGVRPGGWAFQYWN
DYYPDVDDTAVVVMALHRADPDCYSEAIARGAEWIIGMQSGNGGWGAFDVNNEHHFLQHI
PFADHGALLDPPTADVSARCLSMMAQLGYGLDNQAVARAIGYLKRGQEVNGSWYGRWG
>T2AZE4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLATHAMLEANLSSGPRILENDSTSKACKWLENLQIKDCAGDWAVWRPNLRPGG
WAFQYHNDYYPDIDDTAVVAMALHRTGDKIYEPALLRAAEWIIGMQSKNGGWAAFGADNE
YHLLENMPFADHGALLDPLSADVSARCISLLTQIGYDQTNGTIKRGIEYLKKNQEEDGSW
YGSWG
>T2AYD8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAICANALLDSGLPSDHPALVKAGEWIINKQVVKRGDWHVKNFDADPGGWAFEFY
NELYPDTDDTAEILLFLNRVDVKDNRWKLSECQRAMDWLLSMQSKSGGWGAFDIDNDKNI
LNEVPFADHKALLDPATVDVTSRILWMLAKWGFKKEHPQVQRAIEFVKQHQEVDGCWYGS
WG
>T2B084|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLATHAMLEANLSSGPRILKNDSTSKACNWLENLQIKDCVGDWAVWRLNLRLGG
WAFQYRNDYYPDIDDTAVVAMALHRTGNKIYDPTLLRAAEWIIGMQSKNGGWAAFDADNE
YHLLENMPFADHGALLDPPSADVSARCISFLTQMGHDQTNQTIKRGIEYLKKNQEKDGSW
YGRWG
>T2B022|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWIAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGRW
G
>T2AZ24|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSIATIALREAGVSADDPAIRKSVSWLLSKEVREPGDWSVRNKSCEPSGWFFEFN
NRYYPDVDDTSMVVMALRRSLPAMATEGWDADFLLDKWGPHAADKDAVAVLSVRINSPED
LRVGMESITPQLSAIWRGARWVLAMQNKDGGWGAFDANNTRELYTQVPFADHNAMIDPSS
ADLASRMLETFADLNVPCEHPALQRALKYIW
>T2AZM1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTSLNGLSLLESGLTLNDNAIQKACKWLEKNQILEMKGDWIVNNKNLLPGGWSFQY
ENDFYPDVDDTAVVGMFLDRAGYQNKKRLERACNWIAGMQSKNGGWGSFDKDNTDHYLNN
IPFADHGALLDPPTADVSARCVSMLSQINKKNYKNEIQKGIKFLKNEQEEDGSWYGSWG
>T2AZZ2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAVHAMLEAGEPKNGARLNKAMRWMADRQVCDVSGDWATHRPGLRPGGWAFQY
ANDHYPDVDDSAVVAMALDRASDPKVKQGLPRAVEWIVGMQSKNGGWGSFDAENSHYHLN
HIPFADHGALLDPPTEDVTARCVGMLAQIGDEAGNDAIERGLSYLRETQQPDGSWYGSWG
>T2AXP8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANLEPDKTIMEKGAKWFVERQILDVIGEWGANAHGVRPGGWAFQY
WNDYYPDVDDTDVVVMALHRSDPNRYSEAIARGAEWIIGMQSGNGGGGAFELDNEHHFLQ
HIPFADQGAVLDPPTADVSARGLSMRAQLGYGPDHQAVASDIALLK
>T2AXI2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAITLLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGRW
G
>T2AZG8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGRW
G
>T2B085|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAIVSIALRESGISEDDPRIRESCDWLIDREIRFRGDWYHKNPVEVEPSGWVFEF
NNKWNPDVDDTAMVLMALRQTPTDNQQRRDESFKRGMEWMKAFQCRDGGWAAFDKDCTKS
ILEKVPFADHNAMLDPECADITARILELLGYEGYPVDDPQVKRGLAYLRSQQETDGSWYG
RWG
>T2AXV5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTANCSNALLDSGLPTDHPALVRAGKWIVSKQVTKRGDWQVKNPEAEPGGWAFEFY
NELYPDTDDTAEILLFLNRVEILDNRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGRWGFNKQHPQVKRAIKFVKERQEVDGCWF
>T2B087|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAITEICLHAGGVSADSKQLRKTTDWILDREIRFHGDWKFKNPTDAEPSGWAFEH
KNKWNPDADDTAMVLMALRRVPGSDRRRRDIAVERGLRWMVTFQCKDGGWGAFDKDCTKD
ILNKVPFADHNAMLDPECADITARILEFLGQEGYSTDNQQVKKAIQFLRDNQEEDGSWFG
SWG
>T2AZV8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAVHAMLEAGEPKNGARLNKAMRWMADRQVCDVSGDWATHRPGLRPGGWAFQY
ANDHYPDVDDSAVVAMALDRASDPKVKQGLPRAVEWIVGMQSKNGGWGSFDAENSHYHLN
HIPFADHGALLDPPTEGVTARCVGMLAQIGDEAGNDAIERGLSYLRETQQPDGSWYGSWG
>A0A3Q9G347|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces luteoverticillatus|TrEMBL
MTATTDGTGESPLPEAEAGHSTTVPAPATAAPGAPKTREAAARAVTLATEHLLARQDAAG
WWKGDLETNVTMDAEDLLLRRFLGVDDERTTAAAARFIRSRQRPDGTWATFHGGPAELSA
TVEAYTALRLAGDAPDAPHMAAASAWVRAQGGVAAARVFTRIWLALFGWWRWEDLPELPP
EIMYLPKWVPLNLYDFGQWARQTIVPLTVVSALRPVRPAPFALDELHTDPRRPAPPRPLA
PATSWDGVFQRLDKALHVYHRLPVAPLRRAALRSAARWIVERQENDGCWGGIQPPAVYSV
IALHLLGYDLRHPVLRAGLESLDRFAVWDEDEDGAPVRMIEACQSPVWDTCLATTALADA
GLPPDHPALVKAADWMLDEQILRPGDWTVKRPHLAPGGWAFEFENDAYPDIDDTAEVVLA
LKRVRHPDPERMEKAIRRAANWAVGMRSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPP
SADVTAHVVEMLAVLGKRHDPRARRGVEWLLGEQEECGAWFGRWGVNYVYGTGSVVPALV
VSGIPVSHPAIRRAVTWLGEVQNPDGGWGEDLRSYRDPEWIGRGASTASQTAWALMALLA
AGERESAVVERGVTWLTDTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYL
HGEPFAETPLEG
>A0A124XEV8|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cepacia|TrEMBL
MNDLTEMATLSAGTVPAGVDAAVARATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNVELEQKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AADGLFPNYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKSIEKLLVVHDDEAYCQPCLSPVWDTSLAAHALLETGDARAEEAVLRGLEWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAVAMDRAQKLRQNDAYRDSIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLI
ANQNEEGLWDEARFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNTTRVTFGL
>A0A1W0YHP1|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia multivorans|TrEMBL
MNDLTDMATLSAGTVPAELDAAVARATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRAVDHVLR
AVDGLFPAYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKSIEKLLVVHEDEAYCQPCLSPVWDTSLAAHALLETRDPRAEQAAVRGLDWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANPHYPDVDDTAVVAMAMDRAQKLNQSDTYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETAL
NSDAARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCALNAAGLGPEDARVKRAAQWL
LSIQNKDGGWGEDGDSYKLNYRGYEPAPSTASQTAWALLGLMAAGEVNNPAVKRGIDYLI
AEQKEHGLWDEARFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNTTRVTVGI
>A0A8K1ZVU8|squalene-hopene cyclase|EC 5.4.99.17|Petrachloros mirabilis ULC683|TrEMBL
MQVQSGINPTKLLAAIAASQRYLLSQQQEAGYWWAELESNVTITAEGVLLHKIWGTDAAR
PMAKVEGYLRSQQRDHGGWELFYGDGGDLSTSVEAYMALRLLGVPAQDPTLTHARDFILS
KGGISKTRVFTKLHLALIGCYEWRGIPSLPAWVMLLPEGSPFTIYEMSSWARGSTVPLLI
VMDRKPVYRVDPVINLDELYLEGRDRATFELPRSNDWRDLFLGLDSLFKLAEDLSLVPLR
EEGIKAAERWVLERQEVTGDWGGIIPAMLNSLLALRTLGYDVHDPIIARGLQAVDNFVLE
TDSAYWIQPCISPVWDTALVMRALAESGLERDHPALVKGGEWLLQKQILDYGDWGVKNRQ
GEPGGWAFEFDNKFYPDVDDTAVVVMALHGAQLPDEAAKQAAIDRAVQWIATMQCRPGGW
AAFDLDNDQDWLNQLPYGDLKAMIDPNTADVTARVLEMVSRCDVSTGTRSIQRALHYLKG
EQEREGCWFGRWGVNYIYGTSGVLAALALIAPQDYRTQIQGGADWLVSCQNHDGGWGETC
FSYNDPTLKGQGTSTASQTAWALIGLLAAAEATGTYASEALDRGVQYLLNTQQEDGTWNE
AYFTGTGFPCHFYLKYHLYQQHFPLTALGRYQTLLAPPAA
>A0A7U7G6E3|squalene-hopene cyclase|EC 5.4.99.17|Parasaccharibacter apium|TrEMBL
MNKTLFRHNMDATVVEQAVRASHTALGKRQKSDGHWVFELEADATIPSEYVLLRHFLDCI
DVELEQKIGVYLRRTQGEHGGWSLYTDGRFDLSASVKAYFALKMIGDDPEAPHMRKARAA
ILHHGGAERSNVFTRIQLALYGEVPWDAVPVMPVELMLLPRKAFFSVWNMSYWSRAVIAP
LLILAAYRPLALNPRGVRVQELFRRPPATIRDWIRGPYRSVWGRVFTGLDKLIRPLVPFI
PHSVHEKAIRVTIDFIEKRLSGGGLGAIYPAMANVIMMYRTLGVPDDDPRVVQAWEAVQG
LLVVKDDEAYCQPCVSPVWDTGLSGLAMLEASTGARGVMPAETAIALKKAAAWLRERQIL
DVRGDWAINAPTLRPGGWAFQYENDYYPDVDDTAVVGMLLHRIDPEENRTAIERAREWII
GMQSSNGGWGAFDIDNNMEVLNHIPFSDHGALLDPPTVDVSARCISFLSQLGHPEDREVI
RKGLDYIRSEQEKSGSWFGRWGTNYIYGTWSVLCALNIAGISHDDPMVRRAVAWLESVQN
DDGGWGEDCASYEGAPQGLYKESLPTQTAWATLGLMAVGRHDSEAVRRGMAYLMQAQDDQ
GEWHEAPYNAVGFPKVFYLRYHGYKQFFPLMALSRYRNLADSNSGQVEFGF
>A0A522XJD3|squalene-hopene cyclase|EC 5.4.99.17|Phormidium sp. SL48-SHIP|TrEMBL
MDTNQLQKSIRATQTYLLNQQHPQGYWWADLESNVTMLAEVILLHKIWGLEDRLPWNKAE
QFFRDEQRDHGGWELFRGDGGELSTSVEAYLGLRLLGVPQDDPALVKAKQFILAKGGISK
TRIFTKMHLALMGAYDWRGIPSIPAWIMLLPGEAPFSIYDMSSWARGSTVPLLIVFDQKP
VYRLNPQVSLDELYAEGVNAARFELPRQGDWSDSFVELDNLFKLGETLNLVPFREQGLKA
AEQWVIERQEASGDWGGIIPAMLNSMLALRSLNYDLADPVVQRGFEAIARFGVETEQHYW
VQPCISPVWDTAWVVRSLVESGIDPDDARIVKGATWLLQQQILDYGDWSVKNPTAEPGGW
AFEFDNRFYPDLDDSAVVVMALNPTQLPNEPQKQAALTRGIRWMLSMQCSNGGWAAFDRD
NDQDWLNALPYSDLKATIDPPTADVTARLLEMAAELDSEAPDSPLQEYSQQFERALAYLL
GEQEQDGSWFGRWGVNYIYGTSGALSALALITPQRHRLALERGANWLLAVQNADGGWGET
CLSYDHPRFKGEGDSTASQTAWALLGLMAVVKGLQVDSAHPWRASIQRGVDYLIETQQPD
GTWQESWFTGTGFPSHFYLRYDYYRLYFPLLALGRFAAEGILHD
>A0A6B3NY13|squalene-hopene cyclase|EC 5.4.99.17|Okeania sp. SIO1F9|TrEMBL
MTEKNKVQQSILASQEYLLNLQKPQGYWWDELESNVTITAEIVLLHKIWQTDKKRPLDKA
KNYLISQQREHGGWELFYGDGGDLSTSIEAYMGLRLLGVAKTDQIMLKAQDFIIKKGGIS
CSRIFTKLHLALIGCFNWQGIPSIPPSIMLLPEDFPFTIYEMSSWARSSTVPLLIVFDKK
PIFSVNPTINLDELYAEGINNASFELPRQYDLTDLFLGLDKAFKFAENFNLMPLREEGLK
AAEKWILERQEVTGDWGGIIPAMLNSMLALRCLEYDVADPVVVRGLEAIDRFGIETEDSY
WVQPCVSPVWDTAWVIRSLVDSGIPPRHPAVVKGGEWLLQQQILDYGDWAVKNKLGKPGG
WAFEFINRFYPDIDDTAVVVMALDAVELPDEELKRVAIARAMEWVASMQCQPGGWAAFDV
DNDQDWLNGIPYGDLKAMIDPNTADVTARVLEMVGCCGLSMDSWRMKRAIAYLEREQEGE
GCWFGRWGVNYIYGTSGVISALAVVAQESHRDFIEKGASWLVGCQNSDGGWGESCWSYND
PSLKGKGKSTASQTAWALIGLLAAGEATGNFAREAIDRGVDFLVSTQNDDGSWLESEFTG
TGFPCHFYIKYHFYPQYFPLMALGRYENLLSG
>A0A7X5XAI6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces malaysiensis|TrEMBL
MSVAREATARAVEHLLSRQDERGWWKGDLETNVTMDAEDLMLRQFLGIQDPDTLDAAARY
LRSQQAPDGTWATFHGGPPELSTTIEAYVALRLAGDEPDAPHMTAASAWVRSRGGVAASR
VFTRIWLALFGWWRWEDLPELPPEIIYFPKWFPLNIYDFGCWARQTIVPLTVVSAKRPVR
PAPFPLDELHTDPRKPNPPLPQAPIATWDGVFQRLDRALHAYHKVALRPLRRSALRSCAR
WIVERQENDGCWGGIQPPAVYSVIALHLLGYDLDHPVMRAGLESLDRFAVWREDGSRMIE
ACQSPVWDTCLAAIALADAGLAPDHPALVKAADWMMAEQIDRPGDWSVRRPGLPSGGWAF
EFHNDNYPDIDDTAEVILALRRVDHPEPARIEAAVRRAMRWTLGMQSKNGAWGAFDVDNT
SPLPNKLPFCDFGEVVDPPSADVTAHVVEMLAHEGRTYDARTRRGISWLLSEQEPSGAWF
GRWGTNYVYGTGSVVPALISAGVPASHPAVRRAVRWLESVQNEDGGWGEDQRSYLDAEWM
GRGASTASQTAWALLALLAAGERGGAAVERGVTWLAETQREDGSWDEPYFTGTGFPWDFS
INYHLYRQVFPVTALGRFVRGEPTGARPRSS
>A0A291SHY6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces malaysiensis|TrEMBL
MTESVGTAIVAGAEALLAHRRDDGAFVFGAHHASPLNTAGALTALHFADPEGSAETIERG
VTWLCETQRDDGGWAMRSVPTEPLTTALAAAALQLVAPRRAASAVRAARDRFEELGGSAA
VPEPVMTALIRQFHTFAGLPQEGAQRRLPLELLLLPGLSRRLLSLRLPIYAGQALAQSAH
RRRGPAGRALDRLARPRALAILRDAYEREGATGGFSTDPWLTGLICLGLARSGQAPDLVR
AAAGWLRSAARPDGSWDLMPLDVTWTNFATAALIEAGRADDPQLIGTREMLHRHQQPEPF
DALGCPAGYWGFSSPRSWPMALETAESSAILLRLPGGAYDPHVRAGLAWLTATQDAAGSW
SLAVRNTKPGGFGPCPQMTAKIVGALLDSGAGADDPRVAKAVRWLVGRQRPDGSFEAMWY
RGGTPGTAAALEALTRAGRTEEHRRAAARARDWLLRTRHPDGSWSTGEGTRPGTVEETAW
ALRGLLAAGPSPADPALAAAARWLVDAQRADGGWNPAPVNEYIRGCARYADDGIAAGLAL
RALAHYRSATATATATRAKDITGDGEGGRP
>A0A7X3YSG4|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp. SB0678_bin_10|TrEMBL
MDLLINFLGRLSQSFFPSAPQSAPLRHRKPHNASLKLVSNNRGVARDVECVQSHTSPSTV
GHAEAVEEALARSTGWLLQQQDSAHGYWVQELEADTTLTSEYMMLRRYLGTVEKEREDRM
VRYLQGAQLEDGGWPIYTGAPMDVSASVKAYFALKLAGVPQDDPGMRRAREAILARGGVV
SANVFTKIALALFGQYEWRGLPSMPPEIVLVPKKFAFNVYAISYWSRAVVIPLLIMLAVR
RECRVSTGQGIEELFCTPRDQINYRHAPPFQKDPKFISWRNFFVWVDRILKIYEKHPLRS
VRKKAMKQAEAWLLDHMQGDGGLGAIYPAMANSIFALMALGYPATHPLIQQALRSIEDLE
IDTPASAGGPSTLHLQPCHSPIWDTALTINALVERGLPPDHEALSRASSWLRSRQTHSVG
DWIVSSPGATPGGWYFQFENELYPDVDDTAAVLTALAKVSPLQPADRDAAIQRGMKWALA
MQSTNGGWGAYDRNNDRLIFNKIPFADHQSLLDPPTADLTGRCLEMLGALGYDRSHPAVA
PALEFLRREQEADGSWYGRWGVNYLYGTWCVIVGLQAIGEDMSAPWIRRAVSWVESKQNM
DGGWGESCLSYADRAWAGKGESAPSQTAWALLTLLTAGLSESLSVARGINFLLRRQLEDG
TWFEPFHAGTGFPRVFYLRYHGYSKYFPMWALAMYRNVRMHGQTRAQGLQDIAQSARQRQ
P
>A0A8J6YND3|squalene-hopene cyclase|EC 5.4.99.17|Phaeovibrio sulfidiphilus|TrEMBL
MEWIGATGEGKALKNPAVSARSASGAPGAHAAGQSSGTGVDDARLDSVIDEASRWLLDQQ
KSDGHWVFELEADATIPSEYILLNHHLNEGIDPAQEARIGNYLRAIQGDHGGWPLYYDGD
FNMSASVKAYYALKLIGDDINAPHMVRAREAILKHGGAEKSNVFTRMTLAMFQQVPWKAC
PSTPVEVVLLPKWAPFHMSKVAYWSRTVMAPLMILCTRKAKAVNPTGIGVRELFREDPWT
LRKWMTNATGHWMGGALIQFDKVLRTAEPLLHRLFQKKAEKWCLDFIEERLNGRDGLGGI
YPAIANTLMAYHELGLPKDHPNYRIAREAVDLLCVRHGDIEYVQPCLSPVWDTCLSSHAL
QEAGLSGKDEPIRKANEWLRERQILDVRGDWISRRPDVVPGGWAFQYRNDHYPDVDDTAV
VVMAMDRSKEGAVNDESIRRAEDWIIGMQSSDGGWGAFEPENTHYFLNYIPFADHGALLD
PPTVDVSARCVGMLVQLGKMRNDPDARNEAAIRKGLDYIFSHQEEDGSWFGRWGTNYLYG
TWSALNALHAAGVDKNDPRVRKAVDYIKGRQQPDGGWGEDCASYWEERKAEVKASTPTQT
AWALMGLMAAGEVHSPEAERGVNYLLNAPRNGGKWDELYYNAVGFPRFFYLRYYGYPAFF
PLWALARYRNQTRGAVLQPFCGM
>A0A384IH25|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. AC1-42W|TrEMBL
MTATTDGSTGAVDPRAASASTITTQPTIAADAALAAARQAAERSVEHLLGRQDEQGWWKG
DLATNVTMDAEDLLLRQFLGIQDPATLHAAAGFIRGEQLGDGTWATFHGGPADLSATIEA
YVALRLAGDRPDDPHMRRAAGWVRDQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMF
FPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPDHPDPPRRAAPVGS
WDGLFQRLDKALHVYHRFAPRPLRRVAMNTAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLDHPVMRAGLESLDRFAVWREDGTRMIEACQSPVWDTCLATIALADAGVAPDHPA
LVRAADWMLAEEIDRPGDWAVRRPDLEPGGWAFEFHNDNYPDIDDTAEVALALRRVRHPD
QDRVNAAIERGVRWTVGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHV
VEMLAVEGRATDPVTRRGIEWLLSEQDPNGGWFGRWGVNYVYGTGSVVPALTAAGLPVSH
PSIRRAVEWLESVQNDDGGWGEDLRSYSEEKWIGQGASTASQTAWALLALLAAGRRDTVA
VTRGITWLTETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFADR
APKREEA
>A0A2N9LZN2|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Sulfotelmatomonas gaucii|TrEMBL
MRKCDPGGWYFEFNNEFYPDTDDTAQVLLALSKVDNPREHYQLRVAERAIQWVLAMQCKS
GGWGSFDKDNTKMIFEYIPFADHNAMLDPPTVDITGRILEMLASYGYSRADKRVEKAVKF
IFNEQEPDGSWFGRWGVNYLYGTYLVLRGLDAIGVDHLEPQVQQAAEWIRMVQNPDGGWG
ETCGSYDDANTRGIGPSTPSQTAWALLGLLAAGDDRSDSIAKGIRWLLTRQQPNGNWEES
TGEGIRRQALYTGTGFPRVFYLAYTIYRDYFPLLALTSYKRAMERAASSF
>A0A552HMB9|squalene-hopene cyclase|EC 5.4.99.17|Microcystis viridis Mv_BB_P_19951000_S68D|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYPDGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKAREFI
LAKGGISKTRIFTKMHLALIDCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTNLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKAVDNFAIQ
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKGVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVKMEENRVKKAFDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSGCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A841UU35|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa BLCC-F108|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKSATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPANDPTLEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWLGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKSNNWSDVFLWLDGLFKWAEKTNLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALDYDVDDPIVARGLKAVDNFGIE
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKAVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGVLSALAFLEPNKYRQQLQKGANWLSGCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWNE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A6P0YK09|squalene-hopene cyclase|EC 5.4.99.17|Okeania sp. SIO1H6|TrEMBL
MTEKNKVQQSILASQEYLLNRQKTEGYWWGELESNVTITAEIVLLHKIWQIDNKRPLDKA
KNYLISQQREHGGWELFYGDGGDLSTSIEAYMALRLLGVAKTDSIMLKAQEFIIKKGGIS
CSRIFTKLHLALIGCYNWQGIPSIPPSIMLLPEDFPFTIYEMSSWARSSTVPLLIVFDKK
PIFSVNPTINLDELYAEGINNASFELPRQYDLTDLFLGLDKAFKFAENFNLMPLREEGLK
AAEKWILERQEVTGDWGGIIPAMLNSMLALRCLEYDVADPVVVRGLEAIDRFGIETEDSY
WVQPCVSPVWDTAWVIRSLVDSGIPPRHPAVVKGGEWLLQQQILDYGDWAVKNKLGKPGG
WAFEFINRFYPDIDDTAVVVMALDAVELPDEELKRVAIARAMEWVASMQCQPGGWAAFDV
DNDQDWLNGIPYGDLKAMIDPNTADVTARVLEMVGCCGLSMDSWRMKRAIAYLEREQEGE
GCWFGRWGVNYIYGTSGVISALAVVAQESHRDFIEKGASWLVGCQNSDGGWGESCWSYND
PSLKGKGKSTASQTAWALIGLLAAGEATGNFAREAIDRGVDFLVSTQNDDGSWLESEFTG
TGFPCHFYIKYHFYPQYFPLMALGRYENLLSG
>A0A3S9NH78|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cenocepacia|TrEMBL
MNDLTEMATLSAGAVPAGVDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKALDKLLVVHDDEAYCQPCLSPVWDTSLVAHALLETGDARAQAAVLRGLEWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLEQTDTYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRAAQWL
LSIQNKDGGWGEDGDSYKLNYRGYEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLV
AQQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A7C7CUH4|squalene-hopene cyclase|EC 5.4.99.17|Nitrospinaceae bacterium|TrEMBL
MKDVTISPSTAIENQGNTYMDFDNRLDSAIHKSRDFLLSRQTEEGYWVDELESNATITAE
LIFFMHFTETVDLEKQKKLTSYLLHKQREDGSWPLYFGGPCDINSTVESYMALKLAGVPE
NRQEMILAREAIFANGGIKDTRVFTKIFLAMFGQISWDVCPAVPVEIILFKNWFPLNIYE
MSSWSRGTVVPLSIVVSHKPVCHPLEGHGVKELFTVGDRELGFEPDGSIFSSWRNFFIYL
DKVIKFVGKSPWKPFRKRALKKALHWVFEHQEEQGDFAGIQPAMLNSLLAYHYGGIPKND
PKWIKGWEAVERFLIDKPEGTLLQACVSPLWDTAIAANALCDSGMSADHPALVKAAEWIL
SKQVVKEGDWAIKNPQAMPGGWAFEFYNELYPDCDDTAEILIFLNRVGLPDSYHKLKESE
RAISWLLSMQCQSGGWAAFDVDNEKEILNQVPFADHGAMLDPPTADVSGRVLWLLGQIGF
NKDHLIVEKVIGFIKDRQESDGSWWGRWGVNYIYGSWLALTGLASIGEDMRQPYVRRAIK
WYEDHQNEDGGWGETCESYKIPSLAGKGNSTASQTAWALMGMIAGGEEKNLVVTRGIEFL
LNRQELHGSWYEDEFTGTGFPSHFFIKYHMYQHFFPLMALGKYRSALRS
>A0A2N9D0E4|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cenocepacia|TrEMBL
MIRRMNKSAPSPWSTLDTAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDR
IDDVRQEKMARYLRANQRLDTHGAWDLYVDGAPDVSCSVKAYFALKAAGDSEQAPHMIRA
RDAIVKLGGAARSNVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNVSIRELFVTPPEQERRYFPPARGMRRLFLALDRAVRHIEPL
MPKRLRQRAIRHAQAWCAERMNGEDGLGGIFPPIVYSYQMMQVLGYPDDHPLRRDCENAL
EKLLVTRPDGSVYCQPCLSPVWDTAWSTMALEQARGVAAPETGETAAGTLRELDERIARA
YDWLAARQVNDVRGDWIENVPADVEPGGWAFQYANPYYPDIDDSALVTAMLDRRGRTHRH
ADGTNPYAPRVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVS
GRVLLCFGVTKRAEDRASLARCIDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALAGE
DKSQPYIARALDWLRARQHADGGWGETNDSYLDPTLAGTNGGESTSNCTAWALLAQMAFG
DCESDSVKRGIAYLQSVQQEDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRL
AGAAAATPAAVAAADTALA
>A0A5N9FRC1|squalene-hopene cyclase|EC 5.4.99.17|SAR202 cluster bacterium|TrEMBL
MVRRARLCGREEPKSGDATTVAQLKHSDVNQAADEAVQRSQDYFRRTQYPEGYWWGELES
NPTMEAEYLMLCHFTGRHDQERWRKICNYILSKQRSDGSWSQYYEAPGDVSTSVECYFAL
KLAGHSPDTEPLRKAREFILSKGGIPKVRVFTKIWLALFGQWDWKGTPNMPPEMIFLPSW
APFNIYEFASWARATVVPMLIILTRQPYCAVPESADIGELYPGGREGTDYHLPKPTGGFG
WSKALYWADKLVGLYQRLPVHPFRGRAERKIIQWVLDHQEADGSWAGIQPPWVYSLITLH
TLGYGPDHEAVKKGFQGFERFALEDEDKCNVQACISPVWDTCIAQLALLESGIDPEDPMV
QSSARWLMDKQIYATADWQVRAKGTRPGGWSFEFDNLIYPDVDDASIVVMALDQVRLPEA
EEPRRADSIQRGVEWMAGMQSKNGGWAAFDKDNNKKYLTKIPFSDFGETLDPPSVDVTAH
LLEMYGRLGYTKENRAVDRGFAYVVSEQEEDGSWFGRWGVNYVYGIGAVLPALEAIGEDM
SQAYIRLAVDWTVAHQNQDGGWGESCGSYVDPNLHGVGPSTASQTAWALLGLVAAGEHES
EAAQRGLVYLAETQLEDGTWDEPYFTGTGFPGYGVGERLKAMPDIGEPSYQGLDMPAGFM
INYHLYR
>A0A5N9CV78|squalene-hopene cyclase|EC 5.4.99.17|SAR202 cluster bacterium|TrEMBL
MVRRARLCGRKEPESGDVTMMAQLKHADVNQAADEAIRRSQDYFRRTQYPEGYWWGELES
NPTMEAEYLMLCHFTGRHDQERWRKVCNYILSKQRNDGSWSQYYEAPGDVSTSVECYFAL
KLAGHSLDTEPLRKAREFILSKGGIPNVRVFTKIWLALFGQWDWKGTPNMPPEMIFLPSW
APFNIYEFASWARATVVPMLIILTRQPYCAVPESADIDELYPGGREGTDYRLPKPTNGFG
WSKALYWADKLVGLYQRLPAHPFRVRAERKIIQWVLDHQEADGSWAGIQPPWVYSLIALH
TLGYGPDHEAVKKGFQGFEGFALEEEDKCNVQACISPVWDTCIAQLALLQSGIDPEDSMV
QSSARWLMDKQIYAAGDWQVRAKNTRPGGWSFEFDNLIYPDIDDASIVVMALDQVRLPEA
EELRRADSIQRGVEWMAGMQSKNGGWAAFDKDNNKKYLTKIPFSDFGETLDPPSVDVTAH
LLEMYGRLGYTREDRAVDRGFAYVISEQEEDGSWFGRWGVNYVYGIGAVLPALEAIGEDM
SQPYIRLAVDWTVAHQNQDGGWGESCGSYVDPNLRGVGPSTASQTAWALLGLVAASEHES
EAAQRGLVYLAETQLEDGTWDEPYFTGTGFPGYGVGERLKVMPDIGKTSYQGLDMPAGFM
INYHLYRNYWPLLALGRYSQAVSGRL
>G8NZ37|squalene-hopene cyclase|EC 5.4.99.17|Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8)|TrEMBL
MSTTPINPSNPGGTAPKQPRFGRLDMAMDLVIGGINRSVEWLMGEQEEPGYWCGELEADS
MLEADYIFMHTLLGSGDRGKMERCINEILRHQNADGGWSLYPGGPSNVHYGVKCYLALKL
MGWSADDPVLVRARENVLSLGGVVECNTFTKIYLCALGQYDYDAVPAVPPEMLLFPNWFY
FNIYEISSWSRGILVPLSVIYSTKPFKKLPPEQGIDELFVGGRANADLHLRWNKKKFFSW
SNFFLMLDRMMHWAERIHIRPLRKIALKKAEKWMLDRFEMSDGLGAIYPAMMNSIIALRY
LGYSEDDPQFIRAMDEFEKLGIEEPEVPDANPARFRMQPCMSPVWDTAYAVFALGEAGVP
KDDPRLLKAADWMLSKEVRHKGDWAVKVKNVEPGGWYFEFNNEFYPDVDDSAQVLLALNC
VQNPRERYQYEVSQRALNWIFAMQCKNGGWASFDKDNTKQIFESIPFADHNAMIDPPTVD
ITGRILEMLSGYGFTRSDKRVEKAVQFILKGQEPDGSWFGRWGVNYLYGTFLVLRGLEAI
GYSYLEPAVQQAAEWIRMVQNTDGGWGETCGTYDDPNQRGVGPSTPSQTAWAILGLLAAN
DTRSDSVAKGIRWLIERQHEDGSWDELMPGRNGESYYTGTGFPRVFYLGYHLYKQYFPLL
ALTTYRKALEREQAEA
>A0A5J6G577|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces viridosporus T7A|TrEMBL
MTATTDGSTGAALPPRVTAASDTDTDTDIPVAAGVPDIAARAMRRATDFLLSRQSDQGWW
KGDLETNVTMDAEDLLLRQFLGIRDEGTTRAAALFIRGEQREDGTWATFHGGPGDLSATI
EAYVALRLAGDPPDAPHLARASAWIREQGGIAASRVFTRIWLALFGWWKWEDLPELPPEL
IWFPAWVPLNIYDFGCWARQTIVPLTIVSAERPVRPAPFPLDELHTDPARPNPPRVLAPV
TGWDGAFQRLDKALHVLRGAVPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSIIA
LHLLGYDLNHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADH
PQLVKAVDWMLGEQIVRPGDWSVRRPHLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVAH
HDPERVDNAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTA
HVVEMLAAEGLAHDPRTRRGVQWLLAEQEPNGSWFGRWGVNYLYGTGSVVPALTAAGISG
SHPAIRRAVAWLESVQNDDGGWGEDLRSYRDARGWSGRGASTASQTAWALMALLAAGERE
SRAVERGVEWLAATQHEDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPL
AGKPRAAGAATAREDTGQEQSLAEAKGS
>A0A4V1NVD2|squalene-hopene cyclase|EC 5.4.99.17|Acidipila dinghuensis|TrEMBL
MSTRFEFPQSGAPEHPDPAKGHQTRGAETQTKGTASATNPAAAGRVRFGRIDADLADVES
SIGRSRDYLFSQQDPAGFWCGELEADSMLEADYIFAHVLLGSGDAGKMERAMTEILRFQN
ADGGWSNYPGGPSNISLSVKGYFAGKLMGMSPDHPAMAKAREWVLAHGGVTECNTFTKIY
LCALGQYDYDAVPAIPPEIVLFPNWFYFNLYEISSWSRAILVPLSIAYAKKPFKKIPAEQ
GIDELFVGGRENADLRLKFDRKKLISWRNFFLVCDRMTHWMERIHIRPLRKVALKKAEKW
MLERLEMSDGLGAIYPGILNSIIAMRCLGYSLDDPQVIRAIDEFEKLGIDAPNGTPDYAE
PTFRMQPCVSPVWDTAQAVYALGEAGVSRNDPRLLKAVDWMLSKEVRHKGDWAVKVRGVE
PGGWYFEFNNEFYPDTDDSAQVLLALNKVDNPRERYQYDVAQRAIEWLFAMQCKNGGWAS
FDKDNTKMIFQYIPFADHNAMLDPPTVDITGRMLEMLAAYGYTRKDKRIEKAIKFIYSEQ
EPDGSWFGRWGVNYLYGTFLVLRGLEAIGVWNHEPQVQQAAEWVRSVQNADGGWGESCGS
YDDPATRGVGTSTPSQTAWAILGLLAAGDDRSDSVAKGIKWLLAHQEEDGSWDESTGEDV
HRQAIYTGTGFPRVFYLAYHLYRNYFPLLALTTYKKALQKA
>A0A841V3H6|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa BLCC-F158|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKAREFI
LAQGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGLNNVKYELPKSNNWSDVFLWLDGLFKWTEKTNLVPFR
QASLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALDYDVDDPIVARGLKAVDNFAIQ
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAIIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKAVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSGCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A513RQK2|squalene-hopene cyclase|EC 5.4.99.17|Bacillus sp. S3|TrEMBL
MRHRVYKEMNRIANQFARDQSEDGAWHYPFETGIATDCSMIILLRTLEISDEEFIKELVK
RIAGKQQEDGSWKLFHDEEKGNLTATVEAYYALLYSGYRNRKDQEIQAARRFIMANGGAA
EVHMFLKIMLAITGQCPWPHFPINIEVMLLPDSFPINLFDFSVYGRANIIPFLILANTNF
RRRTERSPDLSDLFQKKEVRFFTEDQTEEARSLVKLIKKGIQGLKFHGNLRELTLYRAEK
YMLDRIEPDGTYLNYFSTTSLMIYALLARGYTNTHPVITRAVKGLKAMTCQIDGELHCQY
TTASVWNTTLINYALQESGVPYSSATIQKANQYILSRQHLTYGDWVIHEPNLLPGGWGFA
DLNTIHPDIDDTTAALRAIRTLAKEQVDCRQAWDRGINWLISMQNNDGGWAAFEKNVNKK
VLNLLPIEGGKDLLIDPSTVDLTGRTLEFFGNYTHLDQHHPMVKRGIRWLLRQQNSDGSW
VGRWGVYIYGTWAAVTGMVAVGVSPNHPAIQKALTWLREIQNPDGGWGESCKSDTKNCYV
PLGESTRTHTAWALDTLIAATTGVTPEIENGAAFLVDHKEKDWTTTYPKGRGMAGSFYLN
YHCYEYVFPLLSLAHYQKLAGGQLLTDVSHKDVN
>A0A7T4YCP5|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus sp. ISTL7|TrEMBL
MTGSTACADSTDPRLEAAIAHAVDALIARQRADGHWVFELEADTTIPSEYVLLVHYLGEP
ADPAREARIGRYLLRRQNADGGWPLFHGGASDISASVKAYFALKMIGEPADAPAMRRARE
RILALGGAEASNVFTRTLLALYGVMPWRAVPLMPVEIMLLPLWFPFHLSKISYWARTVIV
PLLVLNTLRPCARNPRRVGIEELFRRPSQAARMPGRAPHQGRFWYAVFRGVDVALRVFEP
LSPKTLRRRAIEQAERFVRERLNGDDGLGAIFPAMVNAVMMFDALGVPRDEPAVAQARAA
LDRLLVEHGDETYCQPCLSPVWDTSLTCHAMLEAGGERALAAARRALDWLLPLQVLDVRG
DWTVRRPHLRPGGWAFQYANPHYPDVDDTAVVAMALDRAARGDARWQGGVEPALARAREW
IEGMQSSDGGWGAFEPENTHSHLNSIPFADHGALLDPPTADVSARCLSMLAQLGELPANS
RAAAQALRYLLDEQEVNGSWYGRWGTNYLYGTWSALCALQAAGLGPEAAPVRRAAQWLLS
VQNGDGGWGEDGSSYRLDYRGHDSAPSTPSQTAWALLGLMAAGCRDLPAVARGIDFLLRE
QRADGLWDEQHFTAVGFPRVFYLRYHGYARYFPLWALARYRNLQRVGNPANATGTADAAG
RMPWGM
>A0A1R4GZP3|squalene-hopene cyclase|EC 5.4.99.17|Crenothrix polyspora|TrEMBL
MINDASNETISDTVSGSATPIRSNKYSLDTAIQNAQARLLSLQDKDGFWVFELEADCTIP
SEYIMMMHYLDDIDTSLQAKIAVYLRSRQSQDGSYPLFTGGAGDISCSVKVYYALKMAGD
AIDAPHMLRLKEYILAQGGAAKANVFTRITLAIFEQLPWRGVPYIPAEIMLLPKWFPFHL
DKVSYWSRAVMVPLFVICTLKATAKNPHKVSVLELFVTHPDEEQHYFPEGTLLNKVFLAL
DKFGRGINPLIPNKMRQHALAKAKDWIVERLNGEDGLGCIFPAMVGSYQALMLLGVPEDH
PDMVTARKAIDRLLVINEHDAYCQPCFSPVWDTGLAALALQEADEKGNSKALTNAYDWLK
SKQLSDEPGDWRIARPDLAGGGWAFQYANPHYPDVDDTALVAVAMACSNLPDLEESVHRA
TNWIVGMQSKNGGYGAFDVDNTYYYLNEIPFADHGALLDPPTADVSARCAMLMARLVAKH
AQYRPALERTIAYLRSDQEVDGSWFGRWGTNYIYGTWSVLIALEQTDMPKTDPMYGKAAT
WLKSVQRDDGGWGEDNDSYHDAGLSGQYGFSTAFQTAWAVLGLMAAGEAHSQEVKAGIDF
ILRNQQGDGVWNDKCFTAPGFPRVFYLKYHGYDKFFPLWALARYRNELNKK
>A0A7X1N525|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia franconis|TrEMBL
MNDLSMTQTLGDALPQTLIDDHAPVAAALATGAAPVDALDAAVTRATDAILAAQKDDGHW
VYELEADATIPAEYVLLVHYLGETPDVELEQKIARYLRRIQLPNGGWPLFTDGALDISAS
VKAYFALKMIGDPEDAEHMIRAREAILANGGAEASNVFTRVLLALFGVVTWYAVPMMPVE
IMLLPKWFPFHLSKVSYWARTVIVPLLVLNAKRPVARNPRGVRIDELFRGAPVTTGLLPR
SGHQSKGWFGFFRTVDSVLRVTDGLFPKASRERATKAAVAFVDERLNGEDGLGAIFPAMA
NSVMMYDVLGYPADHPNRAIARKSIDKLLVVHEDEAYCQPCLSPVWDTSLAAHALLETGD
ERAEEAVLRGLEWLRPLQILDVRGDWISRRPDTRPGGWAFQYNNAHYPDVDDTAVVAMAM
HRAAALTKSDVDSNAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPP
TADVSGRCLSMLAQLGEMPATSEPARRAYDYLLKEQEDDGSWYGRWGMNYIYGTWTALCA
LNAAGISLEDARIKRAAQWLVSIQNPDGGWGEDGTSYKLDYRGYEKARSIPSQTSWALLG
LMAAGYVDHPAVARGIEYLKSEQRDHGLWDEERFSATGFPRVFYLRYHGYRKFFPLWALA
RYRNMTRAGEKRVTVGM
>A0A4R4V0C3|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. 7K507|TrEMBL
MTTTEVSGLTGAAAAAVEAARDHLLGLQSPEGWWKAELETNVTMDAEDLLLREFLGIRAD
GDTREAARWIRSRQRADGTWANFFGGPPDPSTTIEAYVALRLAGDAADAGHMRRAAGYAR
AAGGIEGSRVFTRIWLALFGQWSWDDLPVMPPELMFLPSRVPLNVYDWACWARQTIVPLT
VLGSLRPVRGLPFDLPELRAGVRPAQDEKGWGRVFSTLDRALHVYERRPVRPMRTAALRR
AAEWIIARQEADGCWGGIQPPWVYSLMALHELGYGLDHPVMARGLAGLDRFTIRDAKGRR
LEACQSPVWDTVLAMNALADVGLPGDDPAMARAARWVVGEEIRGPGDWSVRRPGLPPGGW
AFEFDNDNYPDTDDTAEAVLALRKSGFPGAEEPIGRAVGWLAGMASRDGGFGAFDADNTR
ELCTKLPFCDFGAVIDPPSADVTAHVVEALSQEGLAETTVVKRAVVWLLKAQEADGSWFG
RWGANHVYGTGSVVPALIAAGVRPGKPAIRRAVAWLEGHQNDDGGWGEDLRSYDDASWIG
RGASTPSQTAWALLALLAAGERSAAVDGGVRWLVDRQRPDGNWDEEHFTGTGFPGDFYIN
YHLYRLVFPISALGRYLGGAKEVRKS
>A0A398B1F4|squalene-hopene cyclase|EC 5.4.99.17|Peribacillus asahii|TrEMBL
MTQHVQPEIDCLIQRLKTDQTTNGAWEYPFEMGITPDAYMIILLTILNMKDEALISSLVE
RIASKQEANGAWKIFEDEKEGNLSVTIEAYYALLYSGHYEKNDPPIRKARQFILSKGGIK
KAKLFTKAMLTITGQIKWPLVFPIPLESILLPPTSPISMYDFSVYSRVHFVPLLLLAHKK
FRIRLSSSPNLQDLYVKKEEREEEQLWEEFRTDEYRSLFSKVQEGVSSLIGLPHSLHSLA
TASAKRYMTDRIESDGTLYNYFSATFFMIFAFLALGYSKDDPIITKAVAGLKAMTTSTNG
YSHVQFTTASVWNTALISYALQEAGVSSQDSVIQKATAYLLSQQQEKYGDWVIHNPQAIP
GGWGFSNGSTMTPDVDDTTASLRALTHQLHAQNNWQRGLNFTLSMQNKDGGFPAFERNVD
KSWITYLPIENADFILSDPSTADLTGRALEFLGNFANIKNPNHVSKQASKWLIRHQESNG
SWFGRWGVCYIYGTWAALTGLAAAGYSSEHYAIQKAVNWLKKIQNEDGGWGESCYSDIHR
TYIPLNTSTITQTAWAVDALIAVSDQPTPAIERGISFLLNQSETSNRAKNYPVGQGLAGY
IYWNYHSYKYLFPLLALSHYRNKYN
>A0A654C549|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. 8Y|TrEMBL
MNDLSLSAVGAPASHAALDHAVTHATDALLAAQFPEGYWLYELEADATIPAEYVLLVHYL
GETADAKLEAKIGRYLRRIQREDGGWPLFRDGAMDVSATVKAYFALKMIGDSPDAPHMQR
ARQAILAAGGAEKVNVFTRILLALFGVVSWRAVPMMPVEIMRLPMWFPFHLSKVSYWART
VIVPLLVLNAKRPVARNPRGVRIDEVFVEPPVNTGMPERAGHQSRGWFTFFRVVDTVLRA
TDGAFPKAGRERAIAEAVRFVDERLNGEDGLGAIFPAMANSVMMYDVLGYPPEHPNRAIA
RKSVDKLLVIDEADDGEAYCQPCLSPVWDTSLAAHALLETGMPKARAAVARGLEWLRPLQ
ILDVRGDWISRRPNVRPGGWAFQFANPHYPDVDDTAVVAMAMERAGRENGTAMFDEAISR
AREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTVDVSARCLSMLAQLGET
PANSEPARRAFDYIVKHQERDGSWYGRWGMNYVYGTWSALCALNAAGVAPTDSRMKRGAE
WLIGIQNADGGWGEDGESYKLDYRGYEQAPSTASQTAWALLGLMAAGLVEHPAVARGIDY
LVRTQQAHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLTREGETRVTAGM
>A0A0N1G4W1|squalene-hopene cyclase|EC 5.4.99.17|Actinobacteria bacterium OK074|TrEMBL
MTATTDGSTGALPPRAASASETPATLPAAARSAGTQDAAERAVRRATDHLLSRQDAQGWW
KGDLETNVTMDAEDLLLRQFLGIQDEKTIQGSALFIRGEQREDGTWASFYGGPGELSVTI
EAYVALRLAGEAPEAPHMAKASAWIRARGGIAEARVFTRIWLALFGWWKWEDLPELPPEI
LFFPKWMPLNIYDFGSWARQTIVPLTVVSASRPVRPAPFPLDELHTDPARPNPPKPLAPL
ASWDGLFQRLDKVASGYRKVAVRPVRRASLKLAARWIIERQENDGCFGGIQPPAVYSLIA
LYLVGYDLKHPVMRAGLASLDRYAVWREDGARMIEACQSPVWDTCLAAIALADAGLPADH
PQLVKAADWMLGEQVVRPGDWAVRRPGLQPGGWAFEFDNDNYPDIDDTAEVVLALRRVRH
HDPERVERAIARGVRWNLGMQSKNGAWGAFDADNTSSYPNKLPFCDFGEVIDPPSADVTA
HVVEMLAVEGLAHDPRTRRGIEWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALTAAGLPA
AHPAIRRAVAWLERVQNDDGGWGEDLRSYDTAGWSGRGASTPSQTAWALMALLAAGERDS
KAVQRGVEWLADTQREDGSWDEPYFTGTGFPGDFSINYHLYRQVFPLTALGRYVHGAPLG
AAAAAAVVKGA
>A0A4V2ZYR4|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia silviterrae|TrEMBL
MPADDLANALGAAPTLDNASALLRAAAPADVSDALDAAVMRATDAILADQRADGHWVYEL
EADATIPAEYVLLVHYLGEEANLELEGKIARYLRRIQLPGGGWPLFTDGAMDVSASIKAY
FALKMIGDAEDAEHMTRAREAILAAGGAEKANVFTRILLALYGVVSWYAAPMMPVEIMLL
PKWFPFHLSKVSYWARTVIVPLLVLGAKRPVAKNPRGVRIDELFRGAPVTTGLNARSPHQ
SKGWFGFFRAVDGVLRITDPLFPAYLRQRAIDAAVAFVDERLNGEDGLGAIFPAMANAVM
MYEVLGYPADHPHRAIARRSLEKLVTVHAEEAYVQPCLSPVWDTSLAAHALIETGDARAH
EAARRGLDWLRPLQILDVRGDWISRRPDTRPGGWAFQYANPHYPDVDDTAVVVAAMRRVD
QIDNTNAYDEPIARAREWVVGMQSGNGGWGAFEPENTHDYLNSIPFSDHGALLDPPTADV
SGRCLSMLAQLDELPVASEPARRAYHYILAEQEADGSWYGRWGMNYIYGTWTALSALNAA
GLEHADSRMKRAAQWLVAIQNDDGGWGEDGTSYKLEYRGYERAASTASQTAWALLGLMAA
GEVNHPAVARGVAWLQATQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRN
LKRDGITHVRVGL
>A0A6G2LVU3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4956|TrEMBL
MTATTDGSTGAASPSRLTAASEHDTDSPEAAGVPDIAARAVRRATDFLLSRQSDEGWWKG
DLETNVTMDAEDLLLRQFLGILDEDTTRAAALFIRGEQREDGTWASFYGGPGELSTTIEA
YVALRLAGDAPDAEHMAKASAWIREQGGIAASRVFTRIWLALFGWWKWEDLPELPPELIW
FPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPANPSPPRPLAPANT
WDGAFQRLDKGLHALRKAVPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLNHPVVRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHPQ
LVKAADWMLGEQVVRPGDWSVRRPHLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHHD
PERLDNAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGLAQDPRTRRGVEWLLAEQEPDGSWFGRWGVNYLYGTGSVVPALTAAGIPTSH
PAIRRAVAWLEKVQNEDGGWGEDLRSYRHAREWSGKGASTASQTAWALMALLAAGERDSE
AVARGVAWLANTQKEDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFTA
KPAEATAAAGSAQALADAKGS
>A0A3S8YGL9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. W1SF4|TrEMBL
MTATTDGGGAITDGADPRHETTTAPAATAVGPSGDGTGLPTGVREAVDRAVGELLARQDP
AGWWKGDLQTNVTMDAEDLLLRQFLGIRDEAVTRAAALFIRGEQRDDGTWATFHGGPPEL
SATIEAYVALRLAGDPPDAPHMTRASAWIRAHGGIAAARVFTRIWLALFGWWSWDQLPEL
PPELVFLPPWVPLNIYDFGCWARQTIVPLTVVSALRPVRRAPFALDELHADARDPSPAKP
LAPLASWDGAFQRMDRALHLYRRVAPRRLRKAAMAAAGRWIVERQENDGCWGGIQPPAVY
SVIALHLLGYDLGHPVMRAGLESLDRFTVWREDGARMVEACQSPVWDTCLAAIALADAGL
PPDHPALVKAADWMLGEEVRRPGDWAVRRPGLAPGGWAFEFHNDNYPDIDDTAEVVLALR
RIRHPEPGRVEAAIARGVSWNLGMQSKNGAWGAFDADNTSPLPNRLPFCDFGEVIDPPSA
DVTAHVVEMLAAEGRAADPRTRRGIAWLLAEQEPEGPWFGRWGTNYVYGTGSVVPALTAA
GIAPSHPAVRRAVRWLESVQNEDGGWGEDQRSYRDRSWAGRGASTASQTAWALMALLSAG
ERDGDAVARGLAYLVETQRPDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHG
EPFGPQRRSIPAAGES
>A0A4P7A165|squalene-hopene cyclase|EC 5.4.99.17|Paenisporosarcina antarctica|TrEMBL
MSNTPSDEIKRIVSILKKDQSDVGTWEYPFETGIITDAYMIILLRSLTIDDEEELIKELV
DRILSKQEDSGAWKLFYDEDGNVSATIEAYYALLYSGYCSDKEVRMQAARHFILSNGGID
KSSSLTKIMLAVTGQIPWSKMFNLPIEFVLLPLSFPLNFFDFSVYGRANIAPLMILTDKK
YTIKTNKSPNISDLYTSKHTRWDEEYVTRVLLKEWSPFLSLIQKKVEDLIGLPKQIQELA
VDKTKQYMLERIEPDGTLYSYFTSTFLLIFALLSLGYKKDEPAVIHAINGLKSMKCQVDG
KTHMQFTTPTIWNTALISYAMQEAGVSESDPVIKKANRFLATRQHYKFGDWVIHSPQSLP
GGWGFSNINTMNPDIDDTTASLRAICKTVNINTNVHTSWDRGIKWVFSMQNDDGGWPSFE
KGVNKSILSMIPIEDAEYLLADPSSADLTGRTLEFFGNFTNLKKSHDSIKLGVNWLFDHQ
EPNGSWYGRWGICYIYGSWAAITGLVAAGISQDHSSIRKSLKWLRDIQNPDGGWGESCKS
DKMKTYVPLGASTLTHTAWALDALIAAEDKVTPEIVNGINYILKNNDKVDWTTAYLKGQG
MAGSFYIHYHGYRYIFPLLALAHYQKKFANDSHTKNS
>A0A8H8Z3P9|squalene-hopene cyclase|EC 5.4.99.17|Nitrosomonas nitrosa|TrEMBL
MSRMSQQISNFINIKKSAFVNQWLKTSSAIASEVDKSKLDHSISDARNALLALQKKDGHW
CFPLEADCTIPAEYILMMHFMDEVDVVLENKLARFIRDQQDMRHGGWPLYYGGAFDLSCS
VKSYYALKLVGDSPDAAHMVRARSAILSHGGAARANVFTRLLLAMYRQIPWRGVPFVPAE
IILFPKWFPFHLRKVAYWSRTVMIPLSILCSLKAKAVNPRDVHISELFTVPPEKERNYFP
VRTSLNRILLYLERIGSWLEPLIPSFVRKLALRRAEQWMVERLNGECGLGAIFPAMVNAY
EALALLGYDYDHPYRKQCRLALQGLLVDEGERAWCQPCTSPVWDTVLTCLALQEDREADQ
RPVLKALDWLIPNQILDEPGDWRAARPDLPGGGWAFQYANPHYPDLDDTAAVAWALHQGD
ADTYRHSLTRAANWLAGMQSTNGGFAAFDIDNTHYYLNEIPFADHGALLDPPSSDVTARC
TGFLAIHGDQQHQEAIKRGLDYLFNEQEANGAWFGRWGSNYIYGTWSVLEAMRLVNIDKN
HMAIRRAVHWLKSVQRDDGGWGETNDSYFDPQRAGQFEVSTSFQTAWALLGLMAAGEAES
PAVERGINYLLKTQCTNGLWAEPWFTAPGFPRVFYLKYHGYSKYFPVWALIRYRALSERK
AA
>A0A3A1R0K4|squalene-hopene cyclase|EC 5.4.99.17|Bacillus salacetis|TrEMBL
MIAELSRLKQGLLERQDEDGAWRYCFENSLMTDAYMIVLIRSLGIKKEGMVKELSQRLLA
QQDEAGCWKIYRDEKDGNLSATVEAYFALLWSGIVNEKDHNMMKAEGYILSKGGLDGVHS
MTKFMLAAHGQYPWNRFFPVPVELILLPSYFPLNFMDFSAYARVHLAPMLLLKSERFTRK
KTSTPDMSGLLVDKEAPYLFREEERSFIDCVKNGIDALSSVPVDLHSAAKRNALNYMLSR
IEPDGSLYSYFSSSFYMIFALLSQGYPKNHPIIIQAIQSMISHQCRREGHPHIQNSPSTI
WDTALICHALQDAGVSGSHPQIRKAGKFLIDHQHTKKGDWSSEAPGAEAGGWGFSQSNTI
NPDVDDTTAALRALKASSVKEEEKALNWKRGVEWVLSMQNKDGGWPAFEKNKQKEILSWV
PMDGAEDAALDRSTADLTGRTLEFLGNHAGWKLGNKPVEKGVDWLNNNQERDGSWYGKWG
ICYIYGTWAALTGLKAAGINDNHKTIKKAKRWLLDIQNNDGGWGESCRSDKEKRYIPLGA
STPSQTAWALDALISTSDYPTKEIDRGMEALLGLLQSADWRTAYPTGAGLPGTFYIHYHS
YNYIWPLTALSKYTSKYMK
>A0A7X3S3J5|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp. SB0666_bin_27|TrEMBL
MDLLINFLGRLSQSFFPSAPQSAPLRHRKPHNASLKLVSNNRGVARDVECVQSHTSPSTV
GHAEAVEEALARSTGWLLQQQDSAHGYWVQELEADTTLTSEYMMLRRYLGTVEKEREDRM
VRYLQGAQLEDGGWPIYTGAPMDVSASVKAYFALKLAGVPQDDPGMRRAREAILARGGVV
SANVFTKIALALFGQYEWRGLPSMPPEIVLVPKKFAFNVYAISYWSRAVVIPLLIMLAVR
RECRVSTGQGIEELFCTPRDQINYRHAPPFQKDPKFISWRNFFVWVDRILKIYEKHPLRS
VRKKAMKQAEAWLLDHMQGDGGLGAIYPAMANSIFALMALGYPATHPLIQQALRSIEDLE
IDTPASAGGPSTLHLQPCHSPIWDTALTINALVERGLPPDHEALSRASSWLRSRQTHSVG
DWIVSSPGATPGGWYFQFENELYPDVDDTAAVLTALAKVSPLQPADRDAAIQRGMKWALA
MQSTNGGWGAYDRNNDRLIFNKIPFADHQSLLDPPTADLTGRCLEMLGALGYDRSHPAVA
PALEFLRREQEADGSWYGRWGVNYLYGTWCVIVGLQAIGEDMSAPWIRRAVSWVESKQNM
DGGWGESCLSYADRAWAGKGESAPSQTAWALLTLLTAGLSESLSVARGINFLLRRQLEDG
TWFEPFHAGTGFPRVFYLRYHGYSKYFPMWALAMYRNVRMHGQTRAQGLQDIAQSARQRQ
P
>A0A525KB62|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp|TrEMBL
MHSVDQKVAIEADLDASIASATRALLDYRQPDGHWVFELEADCTIPAEYVLLRHYLGEPV
DAVLEAKIANYLRRIQGAHGGWPLVHDGDFEMSASVKAYFALKMIGDSPDAPHMARAREA
IRSRGGAIHSNVFTRFMLSMFGVLTWRSVPVLPVEIMFLPSWSPFHLNKISYWARTTIVP
LMVLAALKPRAKNTRGIGIDELFLQPPHSIGMTAKAPHQSWGWFLLFRALDSVLRAIEPL
FPNKLRARAIDSAVAFVEQRLNGEDGLGAIYPPMANTVMMYGVLGKPADYPPRAITRTGI
DKLLVIGEHEAYCQPCVSPVWDTSLACHALLEAGGEGASAPVKQGLDWLLPRQVLDIKGD
WAVKRPEVRPGGWAFQYNNAYYPDLDDTAVVVMAMDRVRRITQSHDYDVAIARGREWIEG
MQSRDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQFGETVRSSRAM
ADGIAYLRRTQLAEGSWYGRWGLNYIYGTWSVLCALNAAGVGHQDPAMRKAVDWLVSIQN
PDGGWGEDATSYRLDYKGFEKAPATASQTAWALLGLMAAGEVGHPAVARGVEYLKGTQTE
KGLWDEQRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLKSTNSRVVGVGM
>A0A5D3FFE9|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura decatromicini|TrEMBL
MTATQQTPQPTDATEPRTAADALDAAREHLLLLQSPRGWWKGELQTNVTMDAEDMLLREF
LGIRTDDDTREAARWIRSQQGADGSWANFHDGPPDLSTTVEAYVALRLAGDPPDADHMLR
AAAHVRGAGGIPATRVFTRFWLAMFGRWPWDELPVVPPEMIFLPRWFPLNVYDFACWARQ
TIVPLTVVAALRPVRPLPFALDELYPGSDAPRPRDRVRPGWDMAFHTLDRALHVYERRPV
KGLRRAALRRAAEWIVARQERDGSWGGIQPPWVYSLIALNLLGYGVDHPVVQRGLDGLER
FTIRDDKGRRLEACQSPVWDTVLAMTALSDAGLPAGHPALERAAGWVIGEEVRGPGDWSV
RRPGLPPGGWAFEFDNDVYPDVDDTAEAVIALNRVRHPLAEPAIERGVRWMAGMASKDGG
FAAFDADNTRALCRRLPFCDFGEVIDPPSADVTAHVVEAMAHRGMADSLLVKRAVVWLLK
AQEPDGSWFGRWGANHVYGTGSVVPALIAAGVRPDKPAIRDAVGWLVRHQRDDGGWGEDL
RSYRDRSWVGHGASTASQTAWALLALLAAGERGEATERGVRWLVDRQRPDGTWDEDHFTG
TGFPGYFYINYHLYRLVFPLSALGRYLKGS
>D5SYK6|squalene-hopene cyclase|EC 5.4.99.17|Planctopirus limnophila (strain ATCC 43296 / DSM 3776 / IFAM 1008 / Mu 290)|TrEMBL
MTSGTFGAKRVDLLAAFEHSAPAEKTRETCVGLQTAIARTRQYLLDQQHSEGFFVAELEG
DTILESEYILLLAFLNEGQSPDAQAAARYLLTKQNTDGSWSNFPGGPIDVSCAVKAYLAL
RITGHAADEPALIRAREAILQAGGVERVNSFTRFYLAMLGLIPYSLCPAVPPEVVLLPDW
FPINLSQMSAWSRTIVVPLSLLWAFQPAVELNDADGHQITIEELYASPEKQLPRFIRGVN
HESNSNGWMNWSRFFFRVDQCLKSIESYGIKPLRSRAVRKCVQWILDRQEMSDGLGAIFP
PIVWTLIGLKCAGFDDQHPMVQKQRDELNRLMLREQDALRLQPCLSPVWDTAISIIALRE
SGVEPDHPALSKARNWLLSKEVRHAGDWSKAHPETPVSGWYFEFNNEFYPDVDDTAMVLI
ALASTLPEEATPLAISHGVLPVQTGWSAESTSRVQALKQLENHRPVLEAMGRGVQWLKAL
QSKDGGWGAFDSDINKELLTKVPFADHNAMLDETNADISARVLEAYAAVGISFNDPSVQR
ALEFIWNDQEDDHAWYGRWGVNYIYGTWQVLVGLTAIGISAHDPRLVRAAGWLKSKQQAC
GGWGETPATYDNPTLRGQGTPTASQTAWAVLGLIAAGEQNSIECQRGVEFLLKTQKHNGT
WDEEEFTGTGFPRVFYLRYHYYPLYFPLMALGRFARAGGRVNFAG
>A0A845TYR4|squalene-hopene cyclase|EC 5.4.99.17|Acidipila sp|TrEMBL
MATRAKIPGWFSGSESFENSGGTLLGDRLQESVERATEYMLGLQAPEGYWLGELEADTTL
ESDYILYLHILGRFDGARVEKLANYVRRRQLPDGGWNIYCGGPAEINATVKAYFGLKLAG
DSADAPHMERARRRVHQLGGLEAINSFERFYLALVGAVEWDLAPAIPPEFLLLPNWFYVN
LYEMSSWSRGILVPLTILYALKPCWPVEKTQHVDELFVDQKRRLRSYEWDSQVVSWRNFF
LALDRGFKLYERMPWKPLRARALKKAEGWLLGHLERSEGLAAIYPAMMNAIFALIALGHS
PEDPLTVREINELCRFELEDNDTIRLQPCRSPLWDTAIAMVALEEAGLPANHPALVRAAG
WLLDNQIEGPGDWMVKNPGVEPGGWAFEFRNDFYPDVDDTAFILMALQRVDFPDRQRMEK
ALRRGITWMVSMQNHDGGWGAFDKNNDCWVLTQVPFADHNAMIDPATADITARVIECLGR
FGWPASHPVIRRALAFLKHDQCADGSWYGRWGVNYVYGTSGVIRSLEALGQECTDWAARG
VAWLSSVQNADGGYGESIASYDDPSLKGKGISTASQTAWGLIGLLASGEQREPATEKAIE
RSVQYLTEQQTGEGTWEESEFTGTGFPSVFYLKYHLYKHYFPLYALARYQNRLSGGPEFR
SLLFAPAETGLDSKGHGSHGHGANGNGLSVNGANGNGVKSHSGAAQHADQHHADHGNGNG
ARSSNGVR
>A0A838BZX8|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia gladioli|TrEMBL
MNDLTDSTTPDGATPNAAPSPAAGAANLPATSAVPAAQDATPTVADHAPAAPAAPAAPAA
PAAPAAPAAPAAPAATAATAATAATAATAATAATAATAATAATPTPVAAEATTQAAAATA
AAPVAAKLPSPAELDAAVTRATDALLAAQQADGHWVYELEADATIPAEYVLLVHYLGETP
NAELERRIGRYLRRIQLPGGGWPLFTDGAPDVSASVKAYFALKMIGDDVEAEHMVRARQA
IHAMGGAEMSNVFTRIQLALFGVVPWFAVPMMPVEIMLLPQWFPFHLSKVSYWARTVIVP
LLVLNAKRPLAKNPLGVRVDELFVNPPVNTGLLPKQGHQSTGWFLLFRGVDGLLRLTDGL
FPRYSRERAIRQAVQFVDERLNGEDGLGAIYPAMANSVMMYAALGYPEDHPNRAIARRSL
DKLLVIKDDESDEAYCQPCLSPVWDTTLAAHALLETGEPRAEAAALRGLEWLRPLQILDV
RGDWISRRPHVRPGGWAFQYANPHYPDVDDTAVVVLAMDRAARLTQSDVDRDAIARAREW
VVGMQSSDGGWGAFEPENTHHYLNNIPFSDHGALLDPPTADVSGRCLSMLAQLGETGLNS
QPAQRALDYLLAEQEADGSWYGRWGMNYIYGTWSALGALNAAGLGHDDPRVKRAAQWLLS
IQNPDGGWGEDGTSYKLDYRGYEPATSTASQTAWALLGLMAAGEVDHAAVARGIDWLIAE
QKTHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRGLKRAGTTRVTVGM
>A0A5C8SUX4|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium sp. WL12|TrEMBL
MREAVNKVEALQRPKTQAISLDDVDHGVARATRALTALSHDDGHICFELEADATIPSEYI
LFHQFRDTKPPEGLEPKIGNYLRRTQEKHGGWALVHEGPFDMSCTVKAYFALKMIGDDIE
APHMRRAREAILSRGGAAQSNVFTRFILALYGEVPWAAVPVMPVEVMFLPKWFPFHLDKV
SYWARCVMVPLFVLQATKPLAKNPRGIGIGELFLTPPSSVRRWPGSPHATWPWTPIFGGI
DRILQKVEGHFPKRIRLRAMEKARAWVSERLNGEHGLGAIFPAMVNTVLMYEAMGYGPDH
PQVRVACDAIEKLVVVKAHEAYVQPCVSPVWDTALAGHALLEAGGTDAEGQARAGLDWLL
PRQVLDIAGDWAAAKPKVRPGGWAFQYANAHYPDLDDTAVVVMAMDRAMRQHGLVANMPD
YTASIARAREWVEGLQSKDGGWAAFDADNNHMYLNHIPFSDHGALLDPPTADVTARVVSM
LSQLGETRESSKALDRGVTYLLNDQEQDGSWYGRWGMNFIYGTWSVLCALNAAGVDPQSP
EIRRSVEWLIRIQNPDGGWGEDASSYKIDPAFEAGSSTASQTAWALLALMAAGECDDPAV
TRGINFLARTQGADGFWNEERYTATGFPRVFYLRYHGYPKFFPLWAMARYRNLKRGNSRQ
VAYGM
>A0A7V2ICP7|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Rokubacteria bacterium|TrEMBL
MLPSATVTGLDSAIARAQAHLLARQAADGHWVGELEADTTITSEQMLFCHLLDRVDRGRE
QKAVRYLRRRQRPDGGFNLWEGGPTNLSATIKAYFAMKMAGVPVDDPAMARARERILELG
GPPRANVFTKILLALFGEYDWNGVPAMPVEIMLFPRQFFFNLYEVSYWSRTVIVPLLIIM
DRKPVRWLPPEQGLDELWPVPRERASLRFRRIPDPFSWRDLFWKNFFIAVDDALKIWERF
SPRPFRRRAVEAARLWLEARLAVPGGLGGIYPAMANAVLALRLLGYPDEHPLITGQLKEI
EALAVEDAHELHYQPCVSPVWDTALAVNALVESGLAPDHPALRRAAEWLLDRQVLVPGDW
QVKRPHVRPGGWAFQYHNDFYPDVDDTAVVLMALHKVRGLDPARVRAARERGLGWVLGMQ
GSDGGWASFDADNNRLYLNNIPFADHGALLDPSTEDLTGRALELLGTYGYRADFEPARRA
LAFLRRTQRADGPWFGRWGVNYIYGTWSVLRGLRAIGEDPAQEYVRRAADWLERHQNPDG
GWGETCESYERPALAGRGPSTPTQTAWALLALLAVGRARGAAVERGVRYLLATQAPDGGW
EDPYWNGTGFPRVFMLKYHLYAKYFPLWALGTYRRTLDG
>A0A525VJH0|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp. CG24A|TrEMBL
MKLIRALLDRLSENFVVSVSEKLELATEPSNNPPLRLVSDKALLSASADTVTRRSPGHSI
SQVDALDDAVRRSQAWFVSRQDASEGYWVAELEADTTLTAEYLMLRRFLNRVDPERERKA
VSYLRAMQLPDGGWPIFYGGPSEISASVKTYFALKLSGVSADEPWMLRARDRILAMGGVV
CANVFTKITLALFDQYDWKGVPSMPPEIMLLPKRFYFSIYAISYWSRAVLIPLLVVFAKQ
PVCRIPREQGIDELYLSPRAQIHYRDVPPFNKEQRWFTPHNFFVQLDRILKLYDQMPLSW
LREKALDEAATWMLEHLKGSGGLGAIYPAMANSIVALRCLGYEVDDPLVQKALREIESLE
VYGTASIDDQQVETLHLQPCHSPIWDTALLMNALIETGMPQDHPSLQKAGAYLLSRQTTT
VGDWKFSSPNAKPGGWYFQFENEFYPDVDDSAVVLMALSKVRIGQTPESQASIRRGMDWV
LAMQGSDGGWGAYDKDNNRIVFNYIPFADHHALLDPSTSDLTGRCLEMLAALGYDQTHPA
VGPALRFLRREQEADGSWYGRWGVNYIYGTWSVLAGLRAIGVDLSDSSIQRAVAWLESKQ
NPDGGWGESCLSYGDPAWSGKGDSTPSQTAWAIMGLMSAGMADAFSVARGIQYLLRHQTK
EGSWEEVRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRTRGTMRADEVRQQVFASGC
HRADH
>A0A6G2YDF8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8382|TrEMBL
MTATPTVQPSESSESKTLSVAREATARAVEHLLSRQDERGWWKGDLETNVTMDAEDLMLR
QFLGIQDPDTLDAAARYLRSQQAPDGTWATFHGGPPELSTTIEAYVALRLAGDEPDAPHM
TAASAWVRSRGGVAASRVFTRIWLALFGWWRWEDLPELPPEIIYFPKWFPLNIYDFGCWA
RQTIVPLTVVSAKRPVRPAPFPLDELHTDPRKPNPPLPQAPIATWDGVFQRLDRALHAYH
KVALRPLRRSALRSCARWIVERQENDGCWGGIQPPAVYSVIALHLLGYDLDHPVMRAGLE
SLDRFAVWREDGSRMIEACQSPVWDTCLAAIALADAGLAPDHPALVKAADWMMAEQIDRP
GDWSVRRPGLPSGGWAFEFHNDNYPDIDDTAEVILALRRVDHPEPARIEAAVRRAMRWTL
GMQSKNGAWGAFDVDNTSPLPNKLPFCDFGEVVDPPSADVTAHVVEMLAHEGRTYDARTR
RGISWLLSEQEPSGAWFGRWGTNYVYGTGSVVPALISAGVPASHPAVRRAVRWLESVQNE
DGGWGEDQRSYLDAEWMGRGASTASQTAWALLALLAAGEGGGAAVERGVTWLAETQREDG
SWDEPYFTGTGFPWDFSINYHLYRQVFPVTALGRFVHGEPTGARPRSS
>A0A0T6AI23|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Rokubacteria bacterium CSP1-6|TrEMBL
MPKFVASRSTVDQAIQRAQDFLLSTQAPDGHWRGELEADSTITSEYLLLCHLIDRVDRER
EQKAVRYLRAGQLPDGGWPLYGAGPADLSATIKAYFALKLAGVSPEDPAMAAARSLIRRA
GGPVAANVFTKITLALFGEYDWAGVPSMPVEIMLLPRWFYFNIYEVSYWSRTVIVPLLIL
MDKKPVKRLPSGLGLAELWPVPRERARLRLPRTRHPISWKNFFIAVDEVLKFWERRGTRP
ARARAVEAARLWLEXXXXXXXXXXXXXXLWLEERLGVPGGLGGIYPAMANAVLALRCLGY
PDDHPLIRGQLKEIEALAVEGLDSLHYQPCVSPVWDTGLAANALVESGLPADHPALQKAT
EWLIDEQVLVPGDWRVKRPDAPPGGWPFQYGNDFYPDVDDSAMVMMALHKIEAPDPERKR
AAVERGLRWVLAMQGRDGGWGSFDADNNRLVLNNIPFADHGALIDPSTEDLTGRALELLG
TLGYRPDYPPAYRGIDFLRRTQLEDGSWYGRWGANHIYGTWSVLRGLRAIGADLQQDCVR
RAVAWLEAKQNPDGGWGESMASYYNPELAGVGDSIPSQTAWALLGLFAAGRVSGPAVERG
IRYLLDTQRPDGAWEDAFWNGTGFPRVFFLKYHFYAKYFPLWALGVYRHTQG
>A0A063BH48|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. lig30|TrEMBL
MDDLLDDQALDAPQTHRASCDLCEVHLAVCGNLAASVPVASLDATITRATDALLAAQKPD
GHWVYELEADSTIPAEYILLVHYLGETPNLELEQKIGRYLRRIQQQDGGWPLFTDGAPNI
SASVKAYFALKVIGDDVNAEHMQRARHAIHAMGGAEMSNVFTRIQLALFGAMPWRAVPMM
PVEIMLLPQWFPFHLSKVSYWARTVIVPLLVLNAKRPIAKNPRGVRIDELFLSPPVNTGL
LPKQPHQHGGWFAFFRVVDQALRAVDGLFPAYSRERAIRQAVAFVDERLNGEDGLGAIYP
AMANSVMMYD
>K9Q5X1|squalene-hopene cyclase|EC 5.4.99.17|Nostoc sp. PCC 7107|TrEMBL
MQTQDRVQVNQVADAIAASQAYLLSMQYPAGYWWAELESNVTITAEVVLLHKIWGTDKTR
PLHKMENYLRSQQRQHGGWELFYDDGGEISTSVEAYMALRLLGVPATDPALIRARDFILQ
RGGISKTRIFTKLHLALIGCYSWRGIPSLPPWIMLLPPAFPVNIYEMSSWARSSTVPLLI
VCDSKPIYQLDQAINLDELYAEGLNQVQYELPRQGDWTDLFLTLDQGFKLAESLNLVPFR
QEGIKAAEKWILERQEATGDWGGIIPAMLNSMLALKCLGYSQNDPIVERGFQAIDNFAIE
TEENYCIQPCISPVWDTAWVIRALIDSGFAPDDPAIVKAGEWLLQKQILDYGDWTVKNRQ
GKPGAWAFEFDNRFYPDVDDTAVVVMALHPAKLPNESLKQAAIARALNWVASMQCRPGGW
AAFDLDNDQEWLNSIPYGDLKAMIDPNTADVTARVIEMLGACDLSIDSRNLERALSYLLA
EQEPEGCWFGRWGVNYIYGTSGVLSALALINPQKYQPNIDKGAAWLVGCQNSDGGWGETC
RTYNDPSLKGQGRSTASQTAWALIGLIAAGEATGKFAMSAIERGINYLVSTQKPDGTWFE
ADFTGTGFPCHFYLKYHLYQQYFPLIALGRYHNIK
>Q3ERU8|squalene-hopene cyclase|EC 5.4.99.17|Bacillus thuringiensis serovar israelensis ATCC 35646|TrEMBL
MNIVIRISKGWVSNLLLYEKVYEEIARRTTALQTMQRQDGTWRFCFEGAPLTDCHMIFLL
KLLGRDKEIEPFVKRLASLQTNEGTWKLYEDEVGGNLSATIQSYAALLASEKYTKEDANM
KRAEMFINERGGVARAHFMTKFLLAIHGEYEYPSLFHLPTPIMFLQNDSPLSIFELSSSA
RIHLIPMMLCLNKRFRVGKKLLPNLNHIAGGGGEWFREDRSPVFQTLLSEVKKIITYPLS
LHHKGYEEVERFMKERIDENGTLYSYATASFYMIYALLALGHSIQSPIIQKAITGIASYI
WKMERGSHLQNSPSTVWDTALLSYALQEAQVPKASKVIQNASGVFTKKTANEESRLECTC
TESIPRWLGLFGCEYDDSRY
>A0A7W4KG13|squalene-hopene cyclase|EC 5.4.99.17|Gluconacetobacter takamatsuzukensis|TrEMBL
MMVNATDTLERPSADVADPAVPMIEIDRAVDAGHAALGRRQNDDGHWVFELEADATIPAE
YVLLEHYLDRIEPALEARIGVYLRRIQGDHGGWPLYHGGKFDLSASVKAYFALKAIGDDI
DAPHMARARAAILDHGGAERSNVFTRFQLALFGEVPWHATPAMPVELMLLPRRAFFSVWN
MSYWSRTVIAPLLVLAALRPRAVNPRGVHVPELFVTPPGQVRDWIRGPYRSPLGRVFKYV
DKVIRPGERLIPEATRRRAIKAAVDFIEPRLNGVDGLGAIYPAMANSVMMFRALGVPDSD
PRAATAWESVRRLLVEHGDEAYCQPCVSPIWDTGLAGHAMIEAASGPEGIRPEETKKKLA
AAAHWLRERQILNVKGDWAINCPDVAPGGWAFQYNNDYYPDVDDTAVVGMLLHREGDPAH
HESIERARQWIIGMQSTNGGWGAFDIDNNMEFLNHIPFADHGALLDPPTADVTARCVSFL
AQLGHPEDRLVIERGIAYLRTDQEAEGCWFGRWGTNYIYGTWSVLCALNVAGVSHDDPAV
VRAVDWLRSVQREDGGWGEDCASYEGATPGIYTESLPSQTAWAVLGLMAAGLRDDPAVAR
GMAYLTRTQKEDGEWDEDPYNAVGFPKVFYLRYHGYRQFFPLMALARYRNLESSNTRRVA
FGF
>G2LJM4|squalene-hopene cyclase|EC 5.4.99.17|Chloracidobacterium thermophilum (strain B)|TrEMBL
MPGFAPRFVQPVVESPLPPAFRSARPAPATAAAVEAAIRKAQAYLLSKQYPEGYWWAELE
ANVTLTAEYVFLHKVLGTDGERTRQFEKIRTYLRRQQREHGGWELYYGDGGELSTSIEAY
FALKLLGDSPDLPHMARARQFILARGGITKARVFTKIHLALFGAFPWEGCPTLPPWIMLL
PDWFPFTIYELASWARSSTVPLLLVSDRKPVVRVPGGDADELYAEGRAQADLSLPNPAGL
LSLGGVFIGFDWMLKLMERFDLSPRRAEALARAEQWTLEHQDDSGDWGGIIPAMLNSLLG
LHCRGYAPTHPVMQKGIAAVERFCIETEDEFHTQPCVSPVWDTGLTILALLDSGLPNDHP
ALVRAGEWLLSKQIFRDGDWRFKNRTGPAGGWAFEFWNDFFPDVDDTAVVTMALHRLKLP
DEAEKQRRLKLAIEWTLSMQSKNGGWGAFDVDNTLEILNDIPYGDLKAMIDPPTADLTGH
ILEMLGVTGYAAPREKVERAIAFIKSKQEPEGCWWGRWGVNYIYGTHMVICGLVALGLDP
REAFIMRGTQWLNSCQNEDGGWGETCASYGDRTLMGVGKSTPSQTAWALLGLMAGGEGKS
DCARRGIEYLVTHQNDDGSWTEAEFTGTGFPNHFYMNYHFYRNYFPLMALGRYRAFART
>A0A846E4P3|squalene-hopene cyclase|EC 5.4.99.17|Sphaerospermopsis sp. SIO1G1|TrEMBL
MQTQERNKVKLLTEAIAASQEHLISIQKQDGYWWAELESNVTITAEAVLLHKIWGTDKTR
PLHKVETYLRSQQREHGGWELFYGDGGEVSTSVEAYMALRLLGVPETDPDLIRAKNFILD
NGGISKTRIFTKLHLALIGCYQWQGLPSLPPWVMLLPEQFPVNIYELSSWARSSTVPLLI
VFDCKPIFKIDQPINLDELYTEGVENVYWELPKSGDWSDIFNILDEGFKLAENLNLVPFR
EEGIKAAEKWIIERQEATGDWGGIIPAMLNSLLALKCLNYDANDPIVSRGLKSIDNFAIE
TESTYCVQPCVSPVWDTAWVIRALIDSGLAPDDPIITKAGEWLIDQQILDYGDWVVKNKQ
GKPGAWAFEFDNRFYPDLDDSAVVVMALYQSKLTNENLKKQTIKRALYWIESMQCQPGGW
AAFDIDNNQEWLNSIPYGDLKAMIDPNTADVTARVLEMLGFCNLSISANKLTKALNYLIN
EQEQEGCWFGRWGVNYIYGTSGVLSALTLIDPQKYRAEIEKGATWLMKVQNSDGGWGETC
FSYHDPSLKGKGDSTASQTAWAIIGLISAMTVMGKKALPTIEQGVNYLIKTQNSDGTWHE
SYFTGTGFPCHFYLKYHLYQQYFPLMALGRYQAVI
>A0A522YRD9|squalene-hopene cyclase|EC 5.4.99.17|bacterium|TrEMBL
MSEWLTPFGQPRFRKPDQWAERLRPAAEESGQVPLPEALRDGIARAHEYLLGRQDRRQGF
WCAELETDSTLESDAVMLYNFLGRGNDPRVPRFAKSILSEQLPDGGWNIYKNGPAEISAT
VKAYWALKFAGFNADHPALAKARERIAALGGIHKVNTYSKFYMALWGLYGWEGVPSIPPE
IMLFPNWFYFNIYQMSSWTRAIVIPLAIIWSERPRLACPPHARLDELFPDARRHVSLKEA
QAPHTLLSWTSFFLFCDRMLKGAEGRGPHWVRVWALKLCEEWVLERLEDSDGLGAIYPGI
LNTILAMKCLGYADTDPRLRAQLREFEALELPKGEKLKMEPCHSPVWDTAIAVIGLAESG
LDRRHPAVVRAVEWLLAKEIRRAGDWRMTNTVGPIGGWAFEFRNDFYPDIDDTAMVMLAL
RHVELDDRLAQTREKACLRGLTWLLSMQSSSGGWAAFDKENTKVILTKIPFADHNAMIDP
PWADITGRVLEFLGYIGYDESYGCVASAVEFIKREQEADGSWYGRWGVNYLYGTWQVLMG
LNAIGADMGQAWVQKGANWLSSVQREDGGWGETCATYADPSLKGAGPSTPSQTAWAILGL
LAAGRGGDPAVERGVAYLLTTQRPDGTWDESEITGTGFPKVFYLGYTMYRHSFPLMALGK
YQDVLRRRAELATVDA
>A0A7G8BSG5|squalene-hopene cyclase|EC 5.4.99.17|Edaphobacter sp. 4G125|TrEMBL
MSKTSGNPQTPTQPRFGRLDLGLDQVVDSIRRSKDWLLDQQHPDGYWCGELEADVMLEAD
YIFMHTLLGTGDPGKMQRAMNEILRHQNEDGGWSLYPGGPSNINYGVKSYLALKLMGWSA
DHPLMVKAREWVLAHGGVIECNTFTKIYLCALGQYDYDAVPAIPPEIVLFPNWFYFNIYE
ISSWSRGILVPLSIIYAKKPFKKLPPEQGIDELFVGGRQNANLHLRWDTKTPISWRNFFL
FFDRLTHWFERVHIRPLRKVAIRKAEKWMLERFEKSDGLGAIYPAMLNSIVALRYLGRSF
DDPQLIRAMDEFEKLGIDCPEGTLDYPTPTFRMQPCFPPVWDTAQAMYALGEAGVDRNDP
RMLKAADWILSKEVRTKGDWAEKVRNVEPGGWYFEFNNEFYPDVDDTGQVLLALNCVDNP
RERYQYEVCQRALNWIWAMQCKNGGWASFDKDNTKMIFQYIPFADHNAMLDPPTVDITGR
MLEMLAQYGFTRKDPRVEKAIQFILKEQEPDGSWFGRWGVNYLYGTFLVLRGLEAMGIWN
HEPAIQQAAEWVRSVQNADGGWGETCGTYDDPNQRGIGPSTPSQTAWALLGLLAAGDTRS
DSVAKGVRWLTERQHEDGSWDELVPGRNGESYYTGTGFPRVFYLGYHLYKQYFPLLSLTT
YQRAMEREAAEQAS
>A0A7X4IJA4|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp. SB0675_bin_23|TrEMBL
MDLLINFLGRLSQSFFPPAPHKAQPRHWNPRTPSLKLVSGNRGVAGDVECVQSRTAPATV
GHAEAVEEALSRSARWLLGQQHPEQGYWVQELEADTTLTSEYVMLRRYIGAVDTEQEARM
VRYLQGAQLEDGGWPIYTGAPMDVSASVKAYFALKLAGVPQDDPGMRRARQAILDKGGVV
SANVFTKIALALFGQYDWKGLPSMPPEVVLAPKKFAFNMYAISYWSRAVVIPLLIVFAVR
RECRIPAERGIEELFCTPRDQINYRYAPPFQKDPEFISWRNFFVWIDRILKVYEKYPLRS
VRKKAMKRAEAWLLEHMQGDGGLGAIYPAMANSIFALMALGYPASHPLVQKALREIEALE
IDTPDSAEGPSTLHLQPCHSPIWDTALTINALIERGLPVDHEALSHASSWLRSRQTQKVG
DWVVSSPGATPGGWYFQFENELYPDVDDTAAVLTALAKVSPLQPADRDEVIQRGLKWALA
MQSSNGGWGAYDRDNDQLIFNKIPFADHQSLLDPPTADLTGRCLEMLGALGYDRSHPAVA
PALEFLRREQEADGSWYGRWGVNYLYGTWCVVVGLQAIGEDMSAPWIRRAVAWVESKQNI
DGGWGESCLSYADRAWAGKGESTPSQTAWALLTLLTAGLSDSLSIARGVNFLLRHQLDNG
TWYEPYHVGTGFPRVFYLRYHGYSKYFPMWALAMYRNVRMHGQTRSQALQDVAQSARQRQ
S
>A0A3S1BS89|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus anaericanus|TrEMBL
MGNVINQVDKEIQRLTEALIEQQQQDGSWRFCFENGTTIDAYVIILFRTLNIENEVLIQQ
LHARILAEQQPDGCWKLFSDEEDGNLSATVEAYYALLYSGYSQITDETMQRAKRYIQSKG
GLGKVNSLLTKSILAATGQSKWPTSISSIPLELLLFPSSFPINFFEFSGYSRVHLTPMLI
MADRDFSIQTTQTPDLSELISQRNDVEEQNSREFQEMQDNIQQGLSRLFGTPHKTHKAAT
TKAEQFILQRIESDGTLYSYASSTILMIFALLALGYDKQHQLITHAVQGITAMQFRSNGT
TTIQNSPSTIWDTALLSYAMQESGIPDDHVVIRRATAYLLSNQQNKLADWSIHNPNPIPG
GWGFSETNTLNPDVDDTSAALRAIKSLSHTDSTYLDSWNRGLHWIISMQNKDGGGPAFEK
NTNKEILTWLAIDGAKSAAIDPSEADLTGRTLEYLGNSAGLGTKHDFIKRGTNWLIHHQE
KDGSWYGRWGICYIYGTWAALTGLKATGISSDHETIQKGVKWLLGIQNQDGGWGESCRSD
RRKFYIPLGESTPSQTAWALDALISVHLQPTAAINKGINRLIASLQEDNWTTTYPTGAGL
PGYIYIHYHSYRYIWPLLTLSHYRRKYGT
>A0A537QDY4|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
DMSASVKAYFALKMIGEDPDAEPMRRARAAILAHGGAARSNVFTRVLLALYGMLGWHAVP
VMPVEIMLLPRAFPFHIGKISYWARTVIVPLLVLQALKPKAHNPRGVRIDELFLEPPAKV
RRPGKAPHQTWRWFLLFEAIDAALRLAEPWFPRKSRRRAIERAEDFVRERLNGEDGLGAI
FPAMANAVMMLDVLGYPKDHSDVRVARAAIDKLLVVKSHEAYCQPCVSPVWDTVLACHAL
LEAGGEEPVERAVRGLKWLAPLQVLDLVGDWGARRPNVRPGGWAFQYANPHYVDLDDTAV
VAMAMDRVAAATGRADFGNAIARAREWILGLQCRDGGWAAFDADNTYHYLNNIPFADHGA
LLDPPTADLTGRCLSMLAQLGEKPESSPAMRRAIEWLRRDQRQDGSWYGRWGLNYIYGTW
SVLCALNAAGIDRASPMVRKAVDWLATIQNADGGWGEDASSYGLDYRGHVPSPSTASQTA
WALLGLIAAGEVAHPAVARGISHLLRTQGPEGFWAEERYTATGFPRVFYLRYHGYAKFFP
LWALARYRNLQRANSSAAVPFGM
>A0A7K2XEL9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID2131|TrEMBL
MTATTDGNAGAVSPRTAVAGETTDTALPEGTAPVPGRTPPEGTAPAPGRLDETAARAAAR
AAEHLLARQDPAGWWKGDLETNVTMDAEDLLLRQFLGILDPDTIRAAALHIRREQREDGA
WATFYGGPGELSATVEAYVALRLAGDPPEAPHMARASAWVRARGGIAAARVFTRIWLALF
GWWRWEDLPELPPELLFLPKWFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELH
TDPARPNPPRPLAPPTGWDGVFQRLDRVLHLYHRVAPRPLRKVAMNLAARWIVERQENDG
CWGGIQPPAVYSVIALHLLGYDLGHPVMRAGLESLDRFAVRREDGSRMVEACQSPVWDTC
LATVALADAGLPPDHPALVKAVDWMLDEEITRTGDWAVRRPGLPPGGWAFEFHNDNYPDT
DDTAEVLLALRRVRHPDPARVEAAAARGARWTLGMQSRNGAWGAFDADNTSPFPNKLPFC
DFGEVVDPPSADVTAHVVEMLAHEGLARDPRTQRGIEWLLAEQEPHGGWFGRWGVNHVYG
TGSVLPALAAAGIPASHPAVRRAVAWLGSAQNEDGGWGEDLRSYQDEQWVGRGASTASQT
AWALIALLAAGERESEPVRRGIAWLVETQLPDGSWDEPYFTGTGFPWDFSINYHLYRLVF
PLTALGRYVYGEPSPRKEG
>A0A0B6S1X4|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia plantarii|TrEMBL
MIRPMKNSDLPLPSLLDAAILRGRDALAQRQSADGSWCFELESDATITAEYILMMHFMGK
IDEARQARMARYLREIQRLDTHGAWDLYVDGAPDVSCSVKAYFALKAAGDSEDAPHMARA
RETILSLGGAARSNVFTRILLATFGQVPWRATPFMPVEFVLFPKWVPISMYKIAYWARTT
MVPLLVLCSLKARAKNPHDVSIRELFVTAPEAERRYFARGGFVRNLFLTIDRVLRPVDAL
IPKALRRRAIRHAEAWCAERMNGEDGMGGIFPPIVYSYQMMDVLGYPEDHPLRRDCENAL
EKLLVERPDGSVYCQPCLSPVWDTAWSTMALEQARAVPDTRDDPQVSEAELQRRIAASYE
WLAGKQVTQVRGDWIENAPAGTPAGGWAFQYENPYYPDIDDSAVVAAMLHQRGRLLARTT
GTDPYAQVVARGLDWMRGLQSRNGGFGAFDADCDRLYLNLIPFADHGALLDPPTEDVSGR
VLLCFGVTGRDEDKPALARAIEYVKATQRADGCWWGRWGTNYIYGTWSVLAGLALAGESA
SQPYIARAIAWLRACQNADGGWGETNDSYLDPALAGTNGGESASNFTAWALLAQMAFGDW
ESESVQRGIRYLLSVQQGDGFWWHRSHNAPGFPRIYYLKYHGYTAYFPLWALARYRRLSQ
AAVTHGVTEGAALAVN
>A0A7C8EZJ0|squalene-hopene cyclase|EC 5.4.99.17|Desulfuromonadales bacterium|TrEMBL
MSTSKYPISTALTSFSTDNAAPVIEPRKTPGKVHHLPPSIWKKMAGDAKSPLEKAIERTR
DFFFREQLPDGYWWAELESNVTITSEYIMLFHFLGMVDKLRERKMARYILSKQTEEGSWA
VWFGGPGEISTTIEAYFALKLAGYTADDPAMVKARDFILSKGGILKARVFTKIFLALFGE
FSWLGVPSMPIELMLLPDWAYFNLYELSSWSRATITPLSVVMAERPVRKLPPWARVQELF
VRPPRPTDYTFSREDGILSWKNFFVGVDHMLKIYETSPIRPFKKKAMGIAEQWILDHQET
SGDWGGIQPAMLNSVLALHCLGYANDHPTVAKGLEALANFCIEDDESLVLQSCVSPVWDT
ALVLVAMQEAGVPTDHPALVKAAQWLLDLEVRRKGDWQVKSPELEPGGWAFEFLNDWYPD
VDDSGFVMLAIKDIKVRDKKHKEQAIKRGMNWCLGMQSANGGWGAFDKDNTKYLLNKIPF
ADLEALIDPPTADLTGRMLEVMGNCNYPKNHPAAVRALEFLKAQQEPEGPWWGRWGVNYL
YGTWSVLCGLEAIGEDVSQPYIKKAVNWLKSKQNLDGGWGEVCESYEDRSLMGSGASTPS
QTSWAMLSLFAAGEVDSQAAARGVEYLLATQKQDGTWDEDAFTGTGFPKFFMIKYHIYRN
CFPLTALGRYRHLTAEKNNSDSL
>A0A5J6HSM5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces alboniger|TrEMBL
MTATTDGSTGAVTPRAASASQPIDTTAAPAGARDAAARALQRSTEFLLSRQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDEHTTRAAALFIRGEQREDGTWATFYGGPGELSTTIEAY
VALRLAGDRPEDAHMARASAWIRGQGGIAASRVFTRIWLALFGWWKWDDLPELPPELIYF
PSWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHIDASDPRPATPLASVASW
DGVFQRLDKALHVYHKVAPRRLREAAMNSAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLEHPVLKAGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQL
VKAADWMLGEQVVRPGDWSVRRPELTPGGWAFEFHNDNYPDIDDTAEVALALRRVAHPDK
ERVDNAIERGVRWTLGMQSKNGAWAAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGRSHDPRTRRGIAWLLAEQEPTGAWFGRWGVNYVYGTGSVVPALITAGLPASHP
AIRRAVSWLESVQNDDGGWGEDLRSYRDRGWAGRGTSTASQTAWALLALLSAGERDATSV
ERAVTWLARTQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPFADGP
GRVPKGG
>F8AZJ1|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Frankia datiscae|TrEMBL
MSSTTDYEVSRETFSDTVAAAAVRARDHLLGLQSDQGWWKGELETNVTMDAEDLLLRQFL
GILTPQEAEETARWIRSQQSEDGTWATFFGGPADLNATFEAYVALRLAGDSPDAPHMRSA
AEFVRANGGIARTRVFTRIWMALFGEWSWDDLPVMPPELVLLPSWFPLNLYDFACWARQS
IMPLTIIGSLRPKRSLGFEIDELRVDVPPKPPAPLRSWPGAFERLDAVLHRYERRPLKLL
RRHALRRAAEWIVVRQEADGCWGGIQPPWVYSIMALTLLGYPMNHPVIVAGLRGLERFTV
RERTPAGMVRRLEACQSPVWDTALAVVALRDAGLAADHPAVVRAARWLADEEVTVAGDWA
VRRPALAPGGWAFEFDNDLYPDVDDTAEVVLAIERILGPGYGQGLGYGQGPGYGQSPRHG
RDTADPSPAPGGLEAAEPQLAARLRDAGRRGVDWTIGMRSAGGVWGAFDADNTRTLPTKL
PFCDFGEVIDPPSADVTAHIVEMLAEVGQANSPITERAVQWLLDNQEPGGSWFGRWGVNH
IYGTGAVVPALIVAGVPADHPSIVRALRWLVEHQRPDGAWGEDLRSYTDDTWIGRGEATA
SQTAWALLALLAADPASSAVERGVRWLVDTQRPDGTWDEPYYTGTGFPGDFSINYHLYRL
VFPLTALGRYLSGRSAS
>A0A426UMH6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. RP5T|TrEMBL
MTATTDGSTGALPPRAAAASETRLDTPVAAGVQEAAARAVQRATDHLLARQDAEGWWKGD
LETNVTMDAEDLLLRQFLGIRDESTTRAAARFIRGEQREDGTWASFYGGPGELSTTVEAY
VALRLDGDAPDAPHMAKASAWIRAQGGIAAARVFTRIWLALFGWWKWEDLPELPPELIYF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPADPNPAKPLAPVASW
DGAFQRLDKALHQLRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLQHPVMRAGLESLDRFAIWREDGSRMIEACQSPVWDTCLATIALVDAGVPADHPQI
VKAADWMLGEEIVRPGDWAVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHDP
QRVENAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLSHDPRTRRGIEWLLAEQEPDGSWFGRWGVNYIYGTGSVVPALTAAGLPASHP
AIRRAVTWLEKVQNDDGGWGEDLRSYKYVKEWSGRGASTASQTAWALMALLAAGERDSKA
VERGIEWLASTQREDGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFSRT
EAR
>A0A3P3U4W5|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus oralis|TrEMBL
MGQNITGIREEIRRWSEELVQRQEPDGTWRFCFENGTTLDAGVIVLFRSLNAGSEALIRS
LHDRILAAQQPEGCWRWYRDDAEGHLSATIEAYYALLYSGYSRREDESLQRAKRYILERG
GIGKATSLLTKALLAATGQREWPASLSLIPIEMLLLPSSFPLSFYDFSGYSRVHLVPLLI
MAERSYSVKTAQTPDLGELYIDRGPEQAPLTREAREPLDHIQSALGHLVGTPQRIRQAAV
KKAEQYLLERIESDGTLYTYASCTVMMVFALLALGYEPQHPVIQRAVEGLSNLQFTVRGG
EDGSYTTIQNSPSTVWDTALLSYALQEAGLPPSHPAIRRAAAYLHGKQHRKHGDWQIHNP
GTVPGGWGFSETNTFVPDVDDTTAALRALGGLYDSDPAFLEAWNRGLNWVWSMQNGDGGW
PAFEKNTDKEMLTWLAIEGAKSAATDPSEADLTGRTLEYLGNFAKLGVRHDWIARGADWL
ISHQKADGSWYGRWGICYIYGTWAALTGLKAVGMPSGHPAIAKGADWLLSIQNADGGWGE
SCRSDQSERYVPLHASTPSQTAWALDALVAVHDRPTPAMERGAARLTELLREDGWPASYP
TGAGLPGYFYVHYHSYRYIWPLLALAHYANKYGDGSP
>A0A6L3W1Q9|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura montaniterrae|TrEMBL
MTTTEAPGLTEAAAAAVEAARDHLLGLQSAEGWWKAELETNVTMDAEDLLLRQFLGIRTD
AETAAAARWIRSQQRADGTWANFYGGPPDPSTTIEAYVALRLAGDAPDAEHMRKAAAYAR
EAGGIEGSRVFTRIWLALFGQWSWDDLPVMPPELMFLPSRVPLNVYSWACWARQTIVPLT
VLGSLRPVRSLPFDLAELRAGRRPARKASGWGKAFNALDRVLHVYEKRPVAPLRKAALRR
AAEWIVARQEADGCWGGIQPPWVYSLMALSLLGYDLDHPVMKRGLAGLDRFTIEDEKGRR
LEACQSPVWDTVLAMNALSDAGAPAGDPALLRAARWVVNEEIRGPGDWSVRRPDLPPGGW
AFEFDNDLYPDTDDTAEAILALRRSGLPEAREPIDRAVRWMSGMASKDGGFAAFDADNTQ
ELCTKLPFCDFGAVIDPPSADVTAHVVEALAKEGHAEAPVTKRAVVWLLKAQEADGSWFG
RWGANHVYGTGGVVPALIAAGVRPDKPPIRRAVAWLEHHQNPDGGWGEDLRSYDDPAWIG
RGTSTPSQTAWALLALLAAGERSPAVEAGVRWLVENQRPDGTWDEDQFTGTGFPGDFYIN
YHLYRLVFPISALGRYLGRDR
>A0A3B1D4Q6|squalene-hopene cyclase|EC 5.4.99.17|hydrothermal vent metagenome|TrEMBL
MNDTTKPQFSELDRGIERSREFLLSRQAREGYWVDELESNATITAELIFFMHMTGQVDAK
KQERLARYLLQTQREDGSWTLFYGGPCDINSTVECYMALKMAGFSPDHEALVRAKQAVLA
GGGIKKTRVFTKIFLALFGQISWDVPPAVPVEVVLLPDNCWMNIYEISSWSRGTVVPLAM
VCAHKPVHKLAPDKGVRELFTDADADENLGFHADGHVFSSWRNFFIHLDGYLKCLGKLSW
KPFRRRALKKAEAWVLSHQEKEGDFGGIQPAMLNSLLALHFSGYAQDHPAIVKGMEAVDR
FLIDKGD
>A0A1L3RL71|squalene-hopene cyclase|EC 5.4.99.17|Granulibacter bethesdensis|TrEMBL
MPKDTPADLASEAISGDMLEQAVLRASMALHRKQQTDGHWVFELEADATIPAEYVLLEHF
LDRIDDDLEHKIGVYLRRIQGDHGGWPLFHEGAFNLSASVKAYYALKAIGDDPDAPHMRR
AREAILAAGGAERSNVFTRIQLALFGQIPWRGVPVMPAELMIAPKWFPINMWKVSYWSRT
VIAPLLVLMDRKPKARNPRNVHVRELFLNDPDRIRDWIRGPFRSGWGHFFKYLDSVLRVV
EPVALKPMRPRSIRLAVDFVRERLNGEDGLGAIYPAMANSVMMYDVLGYSPDHPEAAIAW
ESVRKLLVIKDDEAYCQPCLSPIWDTGLSGHAMAEAEGAVSPGVAAACDWLRNRQITDVV
GDWAEIRPGVQPGGWAFQYNNAHYPDVDDTAVVAMLLHRQGDPAHEESIRKAREWIIGLQ
CRDGGWGAFDADNDKDYLNHIPFADHGALLDPPTADVTARCISFLAQLGNPEDKPVIDRA
MTWLRKEQEADGSWFGRWGTNYIYGTWSVLCAMNVAGVPHDDPAIRRAVNFLLATQREDG
GWGEDEETYDPASGAQPGRYKESTPSQTAWALIGLMAAGEAEHEATRRGIAYLQATQKPD
GEWDEAAYTAVGFPRVFYLKYHGYRQFFPLMALSRYKNLRSSNMKKVSFGF
>A0A7C5C538|squalene-hopene cyclase|EC 5.4.99.17|Chromatiales bacterium|TrEMBL
MESEPPAPDVVESGLERSLSEAADWLLEQQHPEGYWVGMLESNATMEAEWLLAFHFMGYP
YPHVKGLVKGLLERQRSDGAWETYYEAPAGDMNATVECYAALRMVGMPPEAAPMRRAREW
ILGHGGLGRTRVFTRYWLALLGEWPWRHTPNIPPEIIRLPLWMPFNIYHFAQWARATMMP
IALLSASRPVRPLPPERRLDELFPEGRDRFDYRLPRKGRPLSWERFFLGADRVLHGLQER
GWTPGRRRSVVQVIEWIVRHQDADGAWGGIQPPWIYSLMALYDAGYPLTHPVLRKGLEAL
DAHWSYERDGARYIQASESPVWDTLLGLLALDDAGLLDRDPAAVTRAVDWILDHEVRFRG
DWAVKLPDVEPGGWAFERANLHYPDVDDTAVALIVLGRLRDRYRDPARIDAALDRATRWV
LAMQSRNGGWAAFDKDNDRRILTRIPFSDFGETLDPPSVDVTAHVLEGLAVRGLGRDHPA
VQRALEFIRREQEPDGSWFGRWGVNHLYGTAAVLPALQALGMDMSAAWVRKAADWVAAHQ
NEDGGWGETCASYMDPELRGHGPSTASQTAWALMALLAAGPRRYAAPIRAGIRFLVVSQI
GGTWEEPYYTGTGFPGYGVGERVDLTQTEPGAFAQGRELSRGFMINYNLYRHYFPLMALG
RARRAAVTG
>A0A856NKP5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. S1A1-8|TrEMBL
MTATTDGSTGALPPRAAAASEIHPETTPVAAGTVETRDVATHAIQRATDFLLSRQDAEGW
WKGDLETNVTMDAEDLLLRQFLGIRDETTTRAAGLFIRGEQREDGTWATFYGGPGELSTT
IEAYVALRLAGDAPDDPHMARAAAWIRERGGIASARVFTRIWLALFGWWKWDDLPELPPE
LIYFPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDAGDPNPVKPLAP
AASWDGVFQRLDKALHQYRKVVPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVI
ALHLLGYDLQHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPAD
HPQLVKAADWMLGEEIVRPGDWAVKRPHLPPGGWAFEFHNDNYPDIDDTAEVALALRRVR
HHDPERVEHAIGRGVRWNLGMQSKDGGWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVT
AHVVEMLAVEGLSHDPRTRRGIEWLLAHQEPDGSWFGRWGVNYVYGTGSVLPALVAAGLP
ASHPAIRRAVAWLETVQNDDGGWGEDLRSYHEVAEWSGRGASTASQTGWALLALLAAGER
ASKTVERGIAWLAETQLADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEP
SFVHGESFAEVKGG
>A0A544Y7V4|squalene-hopene cyclase|EC 5.4.99.17|Microbispora sp. SCL1-1|TrEMBL
MTGVTAGVATSAARAATALKAARDHLLGLQSPEGWWKGELQTNVTMDAEDLLLREFLGVR
TAEETAEAARWIRSQQRLDGPRSGTWANFHEGPADLSTTIEAYVALRLAGDPPSAPHMRA
AAAYVRGAGGIESARVFTRIWLAMFGQWRWEDLPVIPPEIMFLPPWCPLNVYDWACWARQ
TIVPLTIVTAHRPVRPLPFGLPELRTGRPAPRPPRTGWDAAFAALDRALHRYERHPVAGL
RRAALRRAVEWVVARQEADGSWGGIQPPWVYSLIALHLSGYGIDHPVMRAGLAGLDRFTI
REDGTRRLEACQSPVWDTALAMTALLDAGLPRDHPALARAGEWLLCEEIRGPGDWAVRRP
GLAPGGWAFEFDNDGYPDVDDTAEVILALRRLRRPDARPALERGLRWMAGMACRDGGFAA
FDADNTRELCLRLPFCDFGAVIDPPSADVTAHVVEALAAEGMARSPVVRRAVVWLLRAQE
PDGSWFGRWGANHVYGTGAVLPALVAAGVRPQAPCVRRAVAWLEAHQHPCGGWGEDLRSY
RDPAWIGRGEPTASQTAWALIGLLAAGERGPCVDRGVAWLADSQRPDGTWDEPYYTGTGF
PGDFYINYHLYRLVFPLSALGRYLHAGEEPS
>A0A7X4BKU8|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp. SB0662_bin_26|TrEMBL
MDLLINFLGRLSQSFFPSAPQSAPLRHRKPHNASLKLVSNNRGVARDVECVQSHTSPSTV
GHAEAVEEALARSTGWLLQQQDSAHGYWVQELEADTTLTSEYMMLRRYLGTVEKEREDRM
VRYLQGAQLEDGGWPIYTGAPMDVSASVKAYFALKLAGVPQDDPGMRRAREAILARGGVV
SANVFTKIALALFGQYEWRGLPSMPPEIVLVPKKFAFNVYAISYWSRAVVIPLLIMLAVR
RECRVSAGQGIEELFCTPRDQINYRHAPPFQKDPKFISWRNFFVWVDRILKIYEKHPLRS
VRKKAMKQAEAWLLDHMQGDGGLGAIYPAMANSIFALMALGYPATHPLIQQALRSIEDLE
IDTPASAGGPSTLHLQPCHSPIWDTALTINALVERGLPPDHEALSRASSWLRSRQTHSVG
DWIVSSPGATPGGWYFQFENELYPDVDDTAAVLTALAKVSPLQPADRDAAIQRGMKWALA
MQSTNGGWGAYDRNNDRLIFNKIPFADHQSLLDPPTADLTGRCLEMLGALGYDRSHPAVA
PALEFLRREQEADGSWYGRWGVNYLYGTWCVIVGLQAIGEDMSAPWIRRAVSWVESKQNM
DGGWGESCLSYADRAWAGKGESAPSQTAWALLTLLTAGLSESLSVARGINFLLRRQLEDG
TWFEPFHAGTGFPRVFYLRYHGYSKYFPMWALAMYRNVRMHGQTRAQGLQDIAQSARQRQ
P
>A0A858WWF6|squalene-hopene cyclase|EC 5.4.99.17|Starkeya sp. ORNL1|TrEMBL
MFDTLAAAPSLDTVDRAVDRAAEALAAAQRPDGHWVFELEADCTIPSEYILLRYYLAEPV
DAVLEAKIGRYLRRIQSGAHDGWPLYHDGAFDISASVKAYYALKMIGDDIDAPHMARARA
AIRAKGGAEAVNVFTRIQLALFGAGSWQVVPTMPPELILLPRWFPIHLSKMSYWARTVVV
PLLVLGALQPLARNPRGIKVDELYTGRAARRTSQAADPKWIWTKGFNGLDWLLKAGNGLW
PKKLRARAIQACADWVVERINGVDGLGAIYPAMANSVMMFDCLGYAEDHPARAAARQSVE
RLLVVGAEEAYCQPCVSPIWDTVLAAHAMMEAGGDANEARADAALAWLEPRQVLDVAGDW
AQERPGVRPGGWAFQYNNDHYPDLDDTAVVVMAMDRARHRTGGYSEAIDRGVEWTAGLQS
KDGGWGAFDADNAYHYLNNLPFADHGALLDPPTADVTARAVSMLAQLGEREGPRMQAALA
WLERAQEPEGSWFGRWGVNYVYGTWSVLCALNAAGLPPSHPMVARAVAWLSAIQNPDGGW
GESCDSYALTRTGHVPAPSTASQTGWALLGLMAAGGVDAPAVERGVAWLAANQEADGLWG
QEMYTGGGFPRVFYLRYHGYTKYFPLWALARYRNLKRSNHAVVEHGM
>A0A6M0FS79|squalene-hopene cyclase|EC 5.4.99.17|Okeania sp. SIO1I7|TrEMBL
MIEKNKVKQSILASQEYLLNLQKPEGYWWGKLESNVTITAEIVLLHKIWQTDNKRPLYQA
KLYLISQQREHGGWELFYGDGGDLSTSIEAYMALRLLGISKTDPIMLKAREFIIKLGGIS
CSRIFTKLHLALIGCYNWQGIPSIPPGIMLFPEDFPFTIYEMSSWARSSTVPLLIVFDKK
PIFSLNPTINLDELYAEGINNASFELPRQYNLTDLFLGLDTAFKFLENLNLMPLREEGLK
AAEKWILERQEVTGDWGGIIPAMLNSMLALRCLEYDVADPIVVRGFEAIDRFGIESEDGY
WVQPCVSPVWDTAWVIRSLVDSGIPPSHPAVVKAGEWLLEQQILDYGDWAVKNKLGKPGG
WAFEFINRFYPDIDDTAVVVMALDAVELPDQELKRVAIARAMEWVASMQCEPGGWAAFDV
DNDQDWLNGIPYGDLKAMIDPNTADVTARVLEMVGFCGLSMDSRRVKRAIAYLEREQEGE
GCWFGRWGVNYIYGTSGVISALAVVARESHGGFIERGATWLVGCQNSDGGWGESCRSYND
PSLKGRGKSTASQTAWALIGLLAAGEVTGNFAREAIDKGVDFLVSTQKDDGSWLESEFTG
TGFPCHFYIKYHFYSQYFPLMALGRYENLLSG
>A0A4Q2R816|squalene-hopene cyclase|EC 5.4.99.17|Lichenibacterium ramalinae|TrEMBL
MSLAAVAAHQPASVPASVIDDLDLAIDRAAVALRREQRGDGHFAFDLEADATIPAEYVML
RHFLGEPDDTIEAKIGAYLRRTQEAHGGWPLLHGGPLNVSASVKAYVALRMVGDAAAAPH
MLKARDAILAAGGAAHSNVFTRTALALFGMVPWRAVPVMPIEIMNAPSWFPFHIYRISYW
ARDTLVPLLVLMALKPRGVNPRGIDIPELFVTPPERVRIWPKGTNQVGGWGIIFGALDKV
LQAAEPYFPKGKRQSAIDKAVAFVRARLNGEDGLGAIYPAMANTVMMFRVLGVPDDHPDV
VLARAAVDKLLAIKDDEAFCQPALSPVWDTALSAHALIEAGGASTRAAERGLAWLKPLQV
LDVKGDWAERRPDVRPGGWAFQYRNDHYPDLDDTAVVVMAMDRARSHSGDAGFNESIARA
REWVVGLQSKNGGWAAFDADNTATYLNYIPFADHGALLDPPTADVTARVVSMLAQLGEVP
DTSPAMKRGLDYLLAEQHPEGGWYGRWGFNFIYGTWSVLCALNAAGLPGDAAPVRRAVAW
LLSIQNADGGWGEDDKGYDLAYKGYSPAPSTASQTAWAAIALMAAGEVDHPAVERGIAYL
RASQTEDGFWPEEFFTGTGFPRVFYLRYHGYPKFFPLWALARYRNLKHSNSRTVMVGM
>A0A3A5J9Q1|squalene-hopene cyclase|EC 5.4.99.17|Salinisphaera sp. Q1T1-3|TrEMBL
MSQAPLQTPSGRLALAFQDEILPHVSRTFALTIPELPEPLRIAIGNAYLLCRIADTIEDD
AEMARADKAAWHAEFVNVVESGAGAAAFGTRLAPQLSAATLDEERRLVAHTADVLTVTLG
LGANRQAAIARCVRIMCAGMPEYEGAVTSEGLPTLAHLDRYCYFVAGVVGEMLTSVFTDY
EPEIGEHDAELNRLAVSFGQGLQMTNILKDIWADRERGVCWLPRDLFARHGYDLSAMADI
GHDPAFAAGLSELIGLAHGHLRNALEYTLRIPGEQKGMRRFCLWAIGLALLTLRKIQANP
HFTHASQVKVSRRTVQATVLTTNLAVSDDDRLRYLFHMTAGELPALTPKLADDPAAPIND
IASMPKAQAPRVAPPAGLEAAIEAAASRLHAEQKSDGHWCYECEADCTIPAEYIMMMHFV
GDIDRDVQARVARFIRHKQAAHGGWPLYYGGDMDLSCSVKCYYALKLAGDDVDAPHMVHA
REAIRARGGAGQVNVFTLIALAQFGQVPWRAVPFIPVEVMLMPEISPFHLSKVSYWSRTV
MVPLFILTSLRAMAKNPAGVNVRELFTVPPEQQRDFVPVSSPLQHLFKGLDAVGRRVEPL
IPQMVRKRAIRKAEAWIIERLNGEDGIGAIFPAMVNVYEALGELGYAADHPYRASQRKAL
DDLVFEHGEMANVQPCVSPVWDTGLGILALQEAAGQGDTPPVRAGLDWLAARQVLDGAGD
WRRGHPELAGGGWPFQYANDHYPDLDDTAVIAWAMYNTGDHATYGRAITRATDWLVGMQS
ANGGVAAFDSDNNHEYLNAIPFADHGALLDPPTADVTARVLTLAGLLKRPQDRPFIRRAL
AYLKRTQEADGSWFGRWGTNYVYGTWSVLTALEVLGEDMNQDWIQRAVAYLKGMQRTDGS
WGEDNGTYWDPPRGRADVSTSFQTAWAMLGLMAAGERDTPALARGAAWLIARQASDGIWH
DPEHTAPGFPRVFYLKYHGYTRYFPMWALARYRNLHGATSPMTVDTIETADEV
>A0A7X0L7Z5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. AK010|TrEMBL
MTATTDGSTGALPPRAAAASDTDTHTAGAAGASQAAARAARRATDFLLSLQDAEGWWKGD
LETNVTMDAEDLLLRQFLGIRDEQTTQAAALFIRGEQGEDGTWATFYGGPSELSATVEAY
VALRLAGDAPDAPHMAKASAWIRAQGGIAAARVFTRIWLALFGWWKWEDLPELPPELVFL
PKWVPLNIYDFGCWARQTIVPLTIVSAMRPVRPAPFPLDELHTDPDLPNPPKPLAPPFSW
DGAFQRMDRGLHALRKAAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLEHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLAAIALVDAGLPADHPQL
VKAADWMLGEEIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVILALRRIVHPDP
ERLDRAAARGVRWTLGMQSKNGAWAAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIEWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALTAAGIPAAHP
AIRRAVAWLESVQNDDGGWGEDLRSYKHVREWSGRGASTASQTAWALMALLAAGERDSKA
VERGVEWLAATQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGEPFAEK
LRGSGQAGALPGSATGLPLVEAEGS
>A0A522EKW1|squalene-hopene cyclase|EC 5.4.99.17|Methylovulum sp|TrEMBL
MFTDATNPITACHSPSSSSAIHSNAYDLNKAIDRAQKQLLSLQDKDGFWVFELEADCTIP
SEYIMMMHYLGEIDEPLQAKIANYLRPRQSEDGSYPLFTGGVGDISCSVKVYYALKMAGD
PVDAPHMSRLKDYILSQGGAARANVFTRIALAMFEQLPWRGVPYIPVEIMLLPRWFPFHL
DKVSYWSRTVMVPLFILCSLKATAKNPNKVGILELFVTHPDKERHYFPKRTLLNKMFLGL
DQFGRASQPFVPKALRQYTIKKAKDWFIERLNGEDGLGGIFPAMVNAYEAMLLLGMPKDH
EHVVTARKAIDKLLVINEYDAYCQPCLSPVWDTALAALALQEADKSANEESLNRAYDWLK
SKQLSDEPGDWRIRRPELAGGGWAFQFNNPYYPDVDDTAVVAFAMADSGLADLNESTHRA
ARWIAGMQSKNGGYGAFDVDNTCYYLNEIPFADHGALLDPPTADVSARCAMLMARVADEH
GEYLPALERTINYLRGEQEADGSWFGRWGTNYIYGTWSVLAGLEQSRLPKTDPIYTKAAQ
WLKSVQRADGGWGEDNYSYHDATYSGKYRFSTAFQTAWAVLGLMAAGEAHSPEVKAGIDF
ILRHQQADGVWNDKCFTAPGFPKVFYLKYHGYDKFFPLWALARYRNELNRRASSLLACGI
HTIPGDRRASSRLAGGIHTIPGDRK
>A0A6B3TX23|squalene-hopene cyclase|EC 5.4.99.17|Neobacillus thermocopriae|TrEMBL
MSNITNGIKWIVDKLRKDQSPDGSWNYPFETGISTDAYMIILLRTLEINDEELIRGLCKR
ILNQQEKNGAWKLFYDEKEGNLSTTLEAYYSLLFSGYYCKDHQSLQAAKKFILAKGGLKN
VSTFTKIMLAITGEYKWPSRSSLPIEVILLPPLFPVNFYSFSVFGRANLTPIMILATKKF
SIRTKYTPNLTELHLKRDEEEQWNYSNEWRSILSSIEDGVKRLVGIPKELRNLALKRAEK
YMLDRIEPDGTFYSYFSSTFLMIFALLSLGYKKSDSIITRAIEGLKAMKCKIEGFPHMQY
TTANVWNTSLISFALQSAGMSPEDPMIKRANDYLLKRQHQKFGDWVIHNPNSLPGGWGFS
DVNTMNPDVDDTTASLRSISRISPPELAAWNSGIRWTISMQNDDGGWPAFEKNTDSKLLT
YLPLEKGEFLLIDPSCADLTGRTLEFFGNYTNLSRNHPIIAKGISWLLNNQQKNGSWYGR
WGICYTYGTWAAITGLKAVGISSSHPSIQKAVKWLYSIQNDDGGFGESCYSDIKNEYIPL
KYSTITHTSWVLDALISVSDKPTPAIRKGMVHLLDSLDKNDWTTAYPKGQGMGGAFYIHY
HSYRYIFPLLALSHYQKKFQE
>A0A6L5FLM9|squalene-hopene cyclase|EC 5.4.99.17|Hyphomicrobiales bacterium|TrEMBL
MQPPAAVPAHDSSTALDTGIAVAAEALLAQQQPDGHWVFELEADATIPAEYVLLTHYLGE
PADPILEAKIGAYLRRIQGAHGGWPLFHAGDFDMSASVKAYFALKMIGDASEAAHMRRAR
EAILARGGAAGSNVFTRILLSLYGMVPWRSVPVMPVEIMLLPRWFPFHLSKISYWGRTVI
VPLLVLMALKPRARNPRGVTIDELFVEPPQTVGPPAKAPHQRRALFSLFRGIDAALRAFE
PWMPRSSRQRAIDAAIGFVSERLNGESGLGAIYPAMANTVMMFDVLGYREDHPHRAIARA
AIDKLLIIKDDEAYCQPCVSPVWDTALACHALLETGGERTAQPIGKASDWLMAQQVLDVA
GDWAERRPNVRPGGWPFQYANPHYPDIDDTAVVVLALDRARTRSAHHRHDVAIDRGREWI
VGLQSANGGWAAFDADNTHYYLDNIPFADHGALLDPPTEDVTARCVSMLAQLGERPDNST
AQARAVDYLRRTQHPDGSWYGRWGMNTIYGTWSVLCALNAAGVDRAAPEVRRAADWLVAI
QNADGGWGEDGSSYKLDYRGHEPAPSTASQTAWALLGLMAVGESDHPAVARGVDYLLRMQ
GGDGFWDEAHYTATGFPRVFYLRYHGYAKFFPLWALARYRNLTRGNRRTVDCSM
>A0A536LYE2|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MQTTAAGASNSAPPALDEAIRRTQDYFLRTQHPDGYWVGELETNVCMAAEYLMLTHFLGI
ADSERWRKVVAYLKSQQSADGAWTIYYGGPPDLNATVEAYFALKLAGTSPEEPHMRRARE
FVLSAGGIPRVRVFTKIWLALFGQWDWRGVPALPPELMFLPSWFPLNIYDFASWARATIV
PMLIILTERPVCPIPERARIDELYPAVRKRADYALPKPRNMLSWKGFFHAADAVLRRYDR
VAIKWLREAGYRAAERWIVARQEADGSWGGIQPPWVYSLIALKLRGYPLEHPVMRKGIEG
FEGAWSIEDDNTFNPQACLSPVWDTALAIISLRDSGISDGHPALMQAGQWLLREQVLTGG
DWQVKAKGVEPGGWSFEFENDFYPDTDDTAAVLIALARTHVPEARKAFALERGVHWLRGM
QSANGGWGAFDKDNTRRIVNEIPFCDFGEVIDPPSEDVTAHAVEALSLVGEKESNGSAVR
YLRGEQRVDGSWFGRWGVNNIYGTGSVLPALAAAGEDMSQPYVRRAVSWLLARQNDDGGW
GESCLSYVDPSSIGRGPSTASQTAWALLGLLAAGGDSSDGVVAQAVERAAGYLVETQEED
GQWLEDEFTGTGFPGDFYIKYHLYRNYWPLMALGRYASRM
>A0A6N8Z7M8|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MTLQQTEMRPAVGAQQPAPARATVDSAIDKLHDYFRSIQHESGYWWGELESNNTMEAEYV
MLCRFLGHHNADRERHIVNYLLSKQGADGSWSIYYGAPGDLSTSVECYFALKLCGQDPES
DPMRHAREFILARGGVPKVRMFTRIWLALFGQWEWEGTPRLPTEMILLPDWAPFSIYRFA
SWARGCIVPLSIVLTRHPIRAISPEHAIDELFPDGRDGTDYSLPTPPGFNLPRMVHLIEQ
TAGTIYNRIRFNPFRKIAERKAIKWILEHQEEDGSWGGIQPPWVYSLIALSVCGFDNDHP
AMVKGFEGLEGFGIQKGDKWTVQGCISPVWDTCLTVQALAESGLSADDPMLTHATRWLVD
KQILVGGDWQVQAPQLQPGGWAFEFHNNCYPDIDDTAEVVLALRLGALPGGEDHLRQEAI
ERAVAWVAGMQNRDGGWASFDKNNNHGYVTAITFSDFGEVLDPSSADVTAHVIEMYGKLG
YRAHLPSIQASYRYLRSEQEDNGSWFGRWGVNYIYGLGAVLPSLESIGEDMGQPYIRRAV
QWLVARQNADGGWGESCASYVDPTQHGVGPSTASQTAWAVIALVAAGEADHSATHNGVDY
LLQTQNDDGQWDEPYFTGTGFPGYMKGARVEHIPKPGERGFQGTELSAGFMINYHLYRNT
WPLLALSRYRNRLYSQSPEHSPRRNGHAPA
>A0A6L9QRW9|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura bangladeshensis|TrEMBL
MTTTEEAPRLSGAAAGALDAARAHLLGLQSPEGWWKAELETNVTMDAEDLLLRQFLGIRT
EAETAEAARWIRSQQRADGTWANFHGGPADLSTTIEAYVALRLAGDPPDADHMLAAAKYA
RDAGGIEGSRVFTRIWLALFGQWSWDDLPVMPPELMFLPSRVPLNVYDWACWARQTIVPL
TVLGSLRPVRSLPVDLAELRGGAVPPDGAKGWGRAFNALDRVLHVYEKAPVRPLRRAALR
RAADWIIARQEADGCWGGIQPPWVYSLMALNVLGYGLDHPVIRRGLDGLERFTIRDEKGR
RLEACQSPVWDTVLAMNALGDAGSDPDDPALLRAAHWVIGEEVQGLGDWAVRRPDLPPGG
WAFEFDNDIYPDTDDTAEAILALRKVALPEAEAPIERAIRWLNGMASRDGGFGAFDADNT
RELCTKLPFCDFGAVIDPPSADVTAHVVEALSKEGLAESAVVKRAVVWLLKAQEADGSWF
GRWGANHVYGTGGVVPALIAAGVRPEKPAIRRAVAWLEEHQNSDGGWGEDLRSYDDPAWI
GRGESTPSQTAWALLALLAAGERSAAVDAGVRWLVENQRPDGNWDEDQFTGTGFPGDFYI
NYHLYRLVFPISALGRYLEGAA
>A0A6M0P4A4|squalene-hopene cyclase|EC 5.4.99.17|Weizmannia ginsengihumi|TrEMBL
MMNTDEGIKWIINKLRTDQTPKGSWSYPFETGITTDAYMIILLRTLGINDEELIQGLVKR
IISKQQQNGAWKLFYDEDDGNLTPTLEAYYALLYSGYYKKNDSRLVAAKKFILSNGGVEN
TNIFTKMLLAITGQYEWPSFSPFPVELILLPPSFPINFYQISVFGRSNIAPIMILAAKKY
SKKTKNSPDLSDLLSQRESHTSWERSPEWISFLSFIEKEIKKLSEIPEQLHVKAIERAKT
YMLERIEPDGTLYSYFSSTFLMIFALLALGYSKHDPHITRAVEGLKSMKTDIDGLPHMQY
TTADVWNTSLISYALQNAGVSSDSPVIKQANHYLRTRQHYKFGDWVIHNPDSLPGGWGFS
DIDTINPDVDDTTASLRAIARNVSSDSHDHEAWNRGLHWVISMQNHDGGWPAFEKNVNDK
WIKLVPIEKGEFLLGDPSSADLTGRTLEFFGNYTNLSSSHSIIQKGSKWVLKHQENDGSW
YGRWGICYLYGTWASITGLIAAGLPASHSSIEQSITWIKSIQNHDGGWGESCRSDIQKTY
IPLGTSTVTHTAWALDALIAAADKPTEEIQKGMTYLLTNLNKKDWTTDYPKGQGMAGGFY
IHYHSYQYVFPLLTLANYQRKFINIAKKQ
>A0A532BVL1|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp|TrEMBL
MKLIRALLDRLSDSLFVSVPEKLGLATELSNVPPLRLVSDKSIPSASVDASTRRSTSHSI
SQVDVLDDAVRRSQAWFLSRQHASEGYWVAELEADTTLTAEYLMLRRFLDRVDPDRERKA
VRYLRAMQLPDGGWPIFYGGPSEISASVKAYFALKLSGISADEPFMVRAKDCILAKGGVV
QTNVFTKITLALFDQYDWEGVPHMPVELMLLPKGFYFNIYAISYWSRAVLTPLLIIFAHR
PVCQIPRQQGIDELYFIPRKEIRYWKFPPFNKDQKWFTPHNFFVALDAILKLYDRMPLMW
LREKALHRAATWMLEHIKGSGGLGSIYPAMANSVMALQCLGYQVDDPLVRKALHEIESLE
VYGTVSIGEQRLEALHLQPCDSPVWDTALLMNALIETGMPQDHPSLQKAAAYLVSRQTKT
VGDWKVSSPDAEPGGWYFQSENEFYPDVDDSAVVLMALSKVRMAQTAELQDSIRRGANWV
LAMQGSDGGWGAYDKDNNRIVFNYIPFADHHALLDPSTSDLTGRCLEMLAALGYDQTHPA
VAPALRFLKREQEPDGSWYGRWGVNYIYGTWSVLAGLRAIGVDLSEPYIRRAVAWLESKQ
NPDGGWGESCLSYGDDPAWSGKGDSTPSQTAWAIMGLMSAGMTDAFSVARGVQYLLRQQM
KDGSWEEVRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRTRGKMRADEVRQQVLASG
CHRADR
>A0A849TSZ4|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp|TrEMBL
MNIIKALFNRLSDSLLSTVQGRLDPATELTPVASLRLVSDKPVILASLDSSAARRPIGHA
VSQPDAVDDAIRRSQSWFFNRQHAEGYWVAELEADTTLTSEYVMLRRFLDRVDPDREVKA
VRYLQATQLQDGGWPIYYGGSAEISASVKAYFALKLCGVSADEPFMVRAKERILAMGGVL
QANVFTKITLALFDQYDWEGVPHMPVELMLLPKKFYFSIYAISYWSRAVLIPLLIVFAHR
PVCRIPREQGIDELYPIPRPEVRYWKYPPFNKDQAWFTPHNFFVALDVMLKLYDRMPMRA
LREKALHKAACWMVDHLKGAGGLGAIYPAMANSIMALQCLGYDADDPLVVKALREIEALE
VYDSMTVDGESVPTLHLQPCFSPVWDTALLMNALVEAGVPQDHPSLQKAGRYLMSRQTKA
VGDWIISSPNAEPGGWYFQFENESYPDVDDSAVVIMALSKLKIPGHEDELNESIGRGMRW
VLAMQGSDGGWGAYDKDNNRVVFNYIPFADHKALLDPSTSDLAGRCLEMLGALGYDKTHP
AAGPALAFLKKEQEKDGSWYGRWGVNYIYGTWSVLAGLRAIGEDLSAPYIRRAVAWLESK
QNPDGGWGESCLSYRDDSEVHGKGESTPSQTAWALMALMSAGAVDSFSVARGVQYLLRWQ
MKDGSWEEISHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRSRGKIRADELRHHIQGT
DLYRSKH
>A0A8J6JM31|squalene-hopene cyclase|EC 5.4.99.17|Rubritepida sp|TrEMBL
MPDIDLRRAGHGDTALEGAVRLAREALLRRQQPDGHWVFELEADATIPAEYIMLRCFFGR
RDAAREAAIGRYLRRLQAQEAPSAAGGWPLFHGGPSDISCSVKAYFALRLIGDAADEPHM
ARARAAILAAGGAARSNVFTRCTLAPFGQVPWHSVPVMPPELLLLPKWFPFHIGKISYWA
RTVLVPLTVVMARRPQPVVPIGVDIAELFTTPPHEVREWPGGAHQQEPWSSLFRAVDRAL
QRAQKIFPRTHRIRAEAACEKFDPERLNGEDGLGAIYPAMANAVFMYHVLGVPEGDPRLV
TAWAAIEKLVCEREGETYVQPCLSPIWDTALVAHALMEAGGDDAQAAVGRGLDWLLAREI
TEVRGDWAWQRPRLQPGGWAFQYENAHYPDVDDTAVVVLAMDRHRRLTGAEHPAMDAALR
RATDWTVGMQSKGGGWGAFDADNTHHYLNHIPFADHGALLDPPTADVTGRCLAMLGQLGE
GQARPARDAVDYLLAEQEADGAWYGRWGVNYVYGTWSALTALNAAGVEHEHAAMRRAVAW
LES
>A0A4V2DDQ9|squalene-hopene cyclase|EC 5.4.99.17|Sphingomonas populi|TrEMBL
MATLLETPDLVALADAATTRAAAALADAQRPDGHWVFELEADATIPAEYVLLRHYLGEPR
AVELEAKIGRYLRRIQGAHHGWPLFHGGAFDISASVKAYYALKMIGDDVDAPHMAAARRA
ILAAGGAEAANVFTRIQLALFGAGPWKAVPTLPVELILLPRWFPVHLSKMSYWARTVIVP
LLVLAAKQPVARNPLGITVDELYTGRAKPPESKAADTKRGWTMFFNGLDVVLKGVEGLWP
KRLRARAIQRCVDFTVERLNGEDGLGAIYPAMANSVMMFDCLGYAEDHPHRAIARKSVEN
LLVVKDDEAYCQPCVSPVWDTALAAHAMLEAGGVENEARADAALEWLRPLQVLDVKGDWA
EQRPDVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRAAPRSGADYRAAVERAVEWTMGLQS
KGGGWGAFDADNHHHYLNNIPFADHGALLDPATSDVSARVVSMLGQLGEPLDSPRMREAL
GFLEREQTADGSWFGRWGVNYIYGTWSVLCALNAAGVDAQSAMVRKAVAWLVAIQNKDGG
WGEDCDSYDLAYTGHTPAPSTASQTGWALLALMAAGEVDLPAVERGVRYLAETQAEDGLW
GQEMYTGGGFPRVFYLRYHGYPKYFPLWALARYRNLKRSNDRRVTVGM
>A0A496Y080|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MGEGLQYSVVPEPTTWFEVPESLAEAAAKAAAQAGQALLDLQNREGYWWAELESNVTITA
EYLMLLYLLGLAEPRKIAALAHDIAQRQLDNGGWSIYYGDGGNLSTTVEAYQALKLAGYS
SQDPALKRARAFIQQRGGVLQSRVFTRIFLALFGQVSWAGVPTLPVEFILLPPRSGLSIY
EFSSWSRATIVPLSVVMAKQPVVHVPPELGVGELFSDPAEGFRDHVVQWQPNGLSLDNIF
VLLDRMLKFYQSWPLHPFRRLALHRAESWILEHQEDSGDWGGIQPAMLNSILALHYLGYD
NDHPVIRRGLAALEFFTIAAQDSIRLQSCISPVWDTALTVRALAAAGCPRSHPALVKAGD
WLLRQQILVRGDWSIKKPDLAPGGWAFEFVNNWYPDIDDSAVVLMALKEGLIDPNQHQSA
LDRGIAWCLGLQCKNGGFAAFDIDNTKDWLNSIPFGDLKALIDPPTEDVTGRILEMMGIY
GYTLDHPAAARAYIFLRQTQQPDGCWWGRWGVNYIYGTWSVLLGLKSIGEDMSQPYIRQA
VAWLQGCQNPDGGWGETCESYRRPQLRGRGASTASQTAWALMALMAAGEVNSVEVRKGIE
YLVRTQNAEGRWEEDYFTGTGFPQHFMIRYHLYRDCFPLMALGQYLQARKQQ
>A0A534W8Q6|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MVRGARPARATRRLVIGSESRIERSGIDLVIERAQGWFEREQYPEGYWWAELESNATMDA
EYLLLTHFLGARNEGHWRGVAQDIRNYQRDDGSWAMYHGAPGDLSTSIECYFALKLAGDP
ADAPHLARARAFIRERGGIARARTFTRIWLALFGQWSWDELPVMPPELMLLPASAPFSIY
RFSSWARGTIVPLLLLMNDRPVRPVPTGARLDELRVPDAAPRPPRDGIDRLFRAIDTALR
GYRRLPFHPFRQRARKAAEQWILAHQEADGSWGGIQPPWVYSLMALSALGHPLDHPALRK
GLEGMHDRWMLHHADGRVRVQACLSPVWDTGLSLLALLESGVEPSASMVERAARWLLREE
IRVPGDWCVQVQGVEPSGWAFEFENDLYPDVDDTAVVLLALLKAGAVDPQLRERALRWML
AMQSRNGGWAAFDKDNTSRLPALIPFADFGEMIDPPSADVTGHVIEMLGAFGVGRDHPAM
QRGLRYLYGQQEKEGSWFGRWGVNHVYGTGAVLPGLAAAGEAIDGLAVRRAVRWLSERQN
ADGGWGETCASYVEIEARGRGESTPSQTAWALLALIAAGRADSKAANRGAHFLVDRQRSD
GAWDEESFTGCGFPGYGIGEEHGARIVEGRELSAGFMIRYHLYRNCFPLLALGRYRAALR
GTARAIPSEGGS
>A0A535ADW6|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MSSEGRLVLVGGTEAADGGLRARAGQAIARATQHLAAAQHPHGYWHAPLEANVTMEAEYV
FFNRMLGRERADVDRRMAERLLALQQADGSWPQYPGGPGNLSTTIEAYFAAKLAGHKPDE
PALARARDFILGHGGLARAGVFTRFWLAYFGQFPWAGLPALPVELVLLPPWFPINIYAMS
SWARGTVVPLSLLAAHRPSVRTPPEAALSELWLATPTRADLGFPRSRELITTQNFFLALD
RALKLVGQSPWKPFRRRAIARAIEWLVRHQDKNGQWGGIQPAMLNSVLALHAVGFAPDHP
AMVSGVQGVDDFLVECEGTLMYQPCVSPTWDTALAMKALLESGMDPAHPMLARAGEWLVA
NQIFRPGDWSILNPELEPGGWAFEFANDWFPDVDDSAVILMVLAQLPIAATPAGKRAIAY
GLNWTLGMQSRSGGWGAFDTNNTAEFLNRIPFADMEAMIDPPTEDLAGRLLNLMGVSGYD
PDFGRARRALEFVRRTQRADGSWWGRWGVNFIYGTWSVLDGLAAIGEDLRAPYVRRAVEW
LRARQNADGGWG
>A0A0N1H9Z9|squalene-hopene cyclase|EC 5.4.99.17|Actinobacteria bacterium OV320|TrEMBL
MTATTDGSTGALPPRAAAASETDITIPVAAGVQEAATRAMQRATDFLLAGQDAEGWWKGD
LETNVSMDAEDLLLRQFLGIRDEATTRAAALFVRGEQREDGTWATFYGGPPDLSATVEAY
VALRLAGDAPEAPHMRRASGWIREQGGIASARVFTRIWLALFGWWKWEDLPELPPELLFF
PKWFPLSIYNFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHADPAHPNPAKPLAPVASW
DGLFQRLDKVVRGYRSVAVRRLRGAALNAAARWIIERQENDGAWGGIQPPAVYSVIALHL
LGYDLQHPVMRAGLESLDRYAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQL
VKAADWMLGEQVVRPGDWSVSRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHHDP
ERMDRAIARGVRWNLGMQSKNGGWGAFDVDNTSPFPNRMPFCDFGEVIDPPSADVTAHVV
EMLAVEGLSHDPRTRRGIEWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALTAAGLPAQHP
AIRRAVSWLERVQNDDGGWGEDLRSYQDATRWSARGASTASQTAWALMALLAAGERDSKA
VERGVAWLAQTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFSKQ
PATHAASTEAKGS
>A0A367EVU1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces diacarni|TrEMBL
MTATTDGPAGPGVSGTKNTTRVAPPAAPAAQESVTALAERTAARAVDHLLARQDEAGWWK
GDLDTNVTMDAEDLLLREFLGIRDEPTYAAAARWIRSQQREDGTWATFHGGPGDLSATIE
AYVALRLAGDQAEAPHMTRAAAWVREKGGVARSRVFTRIWLALFGWWRWEDLPEMPPEII
YFPKWFPLNIYDFGCWARQTIVPLTVVCAFRPVHPAPFALDELHRDPAHPRPDATMAPAT
TWDGAFQRIDRALHAYRKVASRRLRRAALREASRWIIERQENDGCWGGIQPPAVYSVIAL
RLLGYDLDHPVLKAGLASLDRFAVWHDADTRMVEACQSPVWDTCLASIALADAGLPRDHP
ALVKAADWMLGEQVVRPGDWSVRRPGLTPGGWAFEFHNDSYPDTDDTAEVALALRRIQHP
DPERVERALARAVRWNLGMQSRDGAWGAFDVDNTSKFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAAEGKQHDPRTRKALAWLLSEQEADGSWFGRWGVNYLYGTGSVLPALVTAGLPTS
HPAIRRAVRWLEKVQNEDGGWGEDLRSYIDSEWAANGTSTASQTGWALMALLAAGEKDGK
AVERGIGWLAETQREDGYWDEPYFTGTGFPWDFSINYHLYRMVFPLTALGRYLHGDGLER
LARRVA
>T2AYG8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWFGRWG
>T2AYF1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWFGSWG
>T2AZ60|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLSGISLSFSGLTLKDIAIKKACTWLEKKQILGMKGDWVANNKNLLPGGWAFQY
ENDFYPDVDDTAVVAMFLDRAGYQNKKRLERACNWIIGMQSKNGGWGSFDKDNTYHYLNN
IPFADHGALLDPPTADVSARCISMLSQINKKNYKNVIQKGVEFLKNEQEEDGSWFGRWG
>T2AZY1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKIIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSRNGGWSAFDVDNEHHFLQ
HISFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSW
>T2AZ33|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDDPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWFGRW
G
>T2AZD0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAAHAVLETLGGNTLLLNKSCDWLSKLQIKEHTGDWGWRRKGLRPGGWAFQHN
NKFYPDVDDTAVVGMALHRQNPEKYADTISRAEEWMIGMQSSNGGWAAFDADNEYYLLEN
LPFADHRALLDPPTADVTARRISFLTQIGTSNNHPISRGLEFLKRNQEEDGSWYGSWG
>T2AZ84|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
TALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPGLSGGGWAFQYSNYY
YPDLDDTSMVAWAMHRTKSKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYLNEIPS
ADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGRWG
>T2B020|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAIVSIALRESGISEDDPRIRESCDWLIDREIRFRGDWYHKNPVEVEPSGWVFEF
NNKWNPDVDDTAMVLMALRQTPTDNQQRRDESFKRGMEWMKAFQCRDGGWAAFDKDCTKS
ILEKAPFADHNAMLDPECADITARILELLGYEGYPVDDPQVKRGLAYLRSQQETDGSWYG
RWG
>T2B0A7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTALVSQALIEAEKNRQSTEIEDALNWLKKQQLSNEPGDWRIQKPELAGGGWAFQY
SNYYYPDLDDTSMVAWAMHRVNSKKYVAPIQRAANWVAGMQSRSGGFGSFDINNTHFYLN
EIPFADHGALLDPPTADVTGRAIALLSLADKEKYAKNIKEGINYIKSEQEDDGSWYGSW
>T2B074|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPFADHGALLDPPTADVTGRAIVLLSLADKKIYTKNIKDGVDYIKSEQEENGSWFGR
>T2AYM4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTCIAQLALLESGIDPEDPMVQSSARWLMDKQIYATADWQVRAKGTRPGGWSFEFD
NLIYPDVDDASIVVMALDQVRLPESEEPRRADSIHRGVEWMAGMQSKNGGWAAFDKDNNK
KYLTKIPFSDFGETLDPPSVDVTAHLLEMYGRLGYTKEDRAVDRGFAYVISEQEEDGSWY
GRWG
>A0A2N9MXS3|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Sulfopaludibacter sp. SbA3|TrEMBL
MSYEMPEFARQSPRHHTEQAARADRNELAGAIRRSCHALLLQQSLEGFWCGELTADTTLE
SDYILLQLWLHQPEGAEWNPPTRARIEKAARAILERQMPDGGFNIYAGGPADISATVKAY
CALKLAGVATESDPMRRMRARILSLGGLQAANSYVKINLSLFGLYPRKYVPTIPPEITLL
PGGVLYEMSSWTRSILVPLSIVQACGNNRRAPEGFNLDELLRPGGSLALPRRRGISLIFH
HLDRAFKVWETRGPKRVRGAAIRQAEKWVLDRTRHTEGLGAIYPAMMYFIMALDALNYPL
DHPDRVEAIRHFESLLLETEGRFVFQPCVSPIWDTALCAFALGEAGVNGDARLTAAADWL
ISKEVRRKGDWSVKRPDTEPSGWAFEFANEFYPDIDDTAMVLLALMHAKGSNPQAQAAAE
RRAIHWLLAMQSEDGGWAAFDVDNNWAVLNEVPFADHNAMLDPTCPDITGRVIECLCRRG
MAADESVRRGVRYLLKVQEKDGSWYGRWGVNYIYGSFLAMRGLIASRSADAVDAVAKAAR
WLRTIQNPDGGWGESCASYERDHFVSAPSCPSQTAWAVLGLLASGDRNSTQVRRGIEFLL
DRQRAGGTWPEDATTGTGFPNVFYLTYGMYRDYFPLLALAASRGYLPQ
>T2AYU1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAICSNALLDSGLPTDHPALVRAGKWIVSKQVTKRGDWQVKNPKAEPGGWAFEFY
NELYPDTDDTAEILPFLNRVEILDNRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGKWGFNKQHPQVKRAIKFVKERQEVDGCWFGR
WG
>T2AYK2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALTMNALIESGVALNHPALDRADAWLRTRQSQKVGDWVVSSPKAKPGGWSFQYE
NDLYPDVDDTSVVITVMAKIHQAETPDFDEVLQRGFHWVLAMQGSDGGWGAYDKDNNKLI
FNKIPFADHQALLDPSTADLAGRCLEMLGTLGYDQSHPAVGPALEFLRKEQEANGSWYGS
WG
>T2B055|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
WDTGLAMHAMLEANSAPHKIFMEKAANWPVKRQILDVIGDWGANVHGVRPGGWAFQYWND
YYPDVDDTAVVLMALHRADSSRYNQAIARGAEWIIRMQSRNGRWGAFDLHNEHHFLQHIP
FADHGALLDPPTADVSARCLSMMAQLGYGPYNQAVARAIGYLKRGQEFNGSWYGRWG
>A0A7Z0QGR7|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. 323S2|TrEMBL
MDAVNATSREALESGVLESSIASATQGVLGFQQSDGHWVFELEADCTIPAEYILLRHYLA
EPVDAVLEAKIGNYLRRVQGAHGGWPLVHDGEFDMSASVKSYFALKMIGDSVDAPHMVRA
REAIHARGGAINSNVFTRFLLAMFGVVTWRAVPVLPIEIVLLPFWSPFHINKISYWARTT
MVPLMVLAALKPLAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFVLFRALDGILRVI
EPMFPKSLRQRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKDENYPPRAVTR
RGIDKLLVFNGDEAYCQPCVSPVWDTTLTAHALLEAGGDIALPAAKQGLDWLIPKQELEV
KGDWAVKRPDVRPGGWAFQYNNAYYPDLDDTAVVVMSMDRMRREHGATGYDAAIDRGREW
IEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETEKTS
KHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVRHNDPMIRQAADWLAS
IQNKDGGWGEDAVSYRLDYKGWEASPSTASQTAWALLALMAAGEVDHPAVARGVEYLIAT
QNKKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A7V8SX02|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Acidoferrum panamensis|TrEMBL
QARDGHWCAELTADSTLESDFILFQLWLYPPNNGRWEPKTRPLIDKAARAILDRQLPDGG
FSIYVHGPSEVSASVKAYVALRLAGLAPGDFRLVRLRECILALGGVQAANSYVKINLSMF
GLYPREHCPSIPPEVALLPFDFLYQMSSWTRAIVISLSLVHAADPRRPVPAGFDLNELWL
AGVNPAFPRDEPALTWRNAFLALDRLLKWWERHGFESVRRKAVERAKDWMIERLNDSDGL
GAIYPPMMYSVMALDVLGYAPDHPLRVEALRQFNSLMVDDGERFFFQPCFSPVWDTAIAA
YALRQADCGREALPRAADWLLAREIRRKGDWSVKRPHTEPSGWAFEYANAFYPDIDDTAM
VMLALSQSSASNGVAQKACQRRALEWLLAMQSSDGGWAAFDAENNWEFLRLVPFADHNAM
LDPACPDITGRVLEALAAHGVDRHHPAVRRGVDWLVRHQEADGSWYGRWGVAYLYGTCFA
LRGLAASGENDREAHVLRAGEWLRSIQNPDGGWGESCASYD
>A0A3Q9KQT8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces griseoviridis|TrEMBL
MTATTDGSTGAMPPRAAAASDTAGTTPETAGVHEAAAHAVQRATDFLLAQQDPQGWWKGD
LETNVTMDAEDLLLRQFLGIRDEATTRASALFIRGEQRPDGTWATFYGGPGELSATIEAY
VALRLAGDRPDAPHMARASAWIRARGGIAAARVFTRIWLALFGWWRWEDLPELPPELLYF
PKWFPLNIYNFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDKDRPNPPKPLAPPTTW
DGLFQRLDKVVRGYRAVAVRGLRTAALNSATRWIVERQENDGAWGGIQPPAVYSVIALHL
MGYDLDHPVMRAGLESLDRYAVWREDGARMIEACQSPVWDTCLAAIALVDAGVPADHPKL
VRAADWMLGEEIVRPGDWAVRRPQLPPGGWAFEFHNDNYPDIDDTAEVALALRRVRHHNP
ERVDRAIGRAVRWNLGMQSKNGGWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLSHDPRTRRGIDWLLAEQEPDGSWFGRWGVNYIYGTGSVVPALTAAGFPGSHP
AIRRAVGWLESVQNEDGGWGEDLRSYQDAARWSGRGASTASQTGWALMALLAAGERDSKA
VERGVAWLAATQRDDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGEPFAKR
PYPEAEGG
>A0A538CYA0|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MTLAPNRTATTLDRAVERATERLLELQHPDGWWVGELESNATMIAQHLFWHHFLGLRTPE
LDRKVANELLARQRDDGTWAIWFEGPPDLSTTIEAYTALKLAGIDPGARARGYICGEGGV
SHARVFTKCFLALLGHWPWQWVARMPPEVILLPPDGPFSVYNFSCWARQTVVPLSVVQAL
RPVRPALIDLREIGARFGQTKPPPRPGPIRRVAFATAERWVRDRQEVDGSWGGIQPPWAW
SIIMLAALGYGFEDETLQAAVEGWRGFTIDEGDRLRPEACQSPVWDTALAVIALLDAGIS
PQHPALRRAGDWLTGQEVTVRGDWAIRRPDLAPGGWAFEFENDLYPDVDDTAVVALALSG
LGIGAGAVERSLAWTAGMQSRSGGWGAFDVDNEAHWLYKLPFCDFGKVTDEPTADVSAHA
LEVLAREPRYATEVQRGLDWLLAEQEPDGSWFGRWGVNHLYGTAASLPALEACGVPSDHP
AIRRAVAWLEAVQQQNGSFGEDIRSYADPSWRGRGRPTPSQTAWALLGYVAAGEAGSDPA
RRAVEWLCSEQQPDGDWQEEQFTGTGFPLDFMIRYHLYRLHFPLMALGRLRERLAA
>A0A0B5DQI4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces nodosus|TrEMBL
MTATTDGSTGALPARADSASETDAPFPQAAGTVGTQDAAEHAMRRATDFLLSRQDAQGWW
KGDLETNVTMDAEDLLLRQFLGIRDERTTHAAALFIRGEQRDDGTWAAFYGGPGELSTTI
EAYVALRLAGDAPHEPHMAKASAWIREQGGVAASRVFTRVWLALFGWWRWEDLPEMPPEL
IYFPKWMPLNIYDFGCWARQTIVPLTVVSALRPVRPAPFPLDELHTDADDPNPARSLAPL
VSWDGVFQRLDKGLHGYRRVAPRRLRRAAMNAAARWIVERQENDGCWGGIQPPAVYSIIA
LHLLGYDLQHPVMREGIASLDRFAVWRDDGARMIEACQSPVWDTCLATIALADAGVPADH
PQLVKAAEWMIEEQIDRPGDWSVRRPQLPPGGWGFEFHNDNYPDIDDTAEVVLALRRVGH
RDRERAEQAIARGVRWNLGMQSRNGAWAAFDVDNTSPFPNRLPFSDFGEVIDPPSADVTA
HVVEMLAVEGLAHDPRTRRGIEWLLSEQEADGSWFGRWGVNYVYGTGSVVPALVAAGVPG
AHPAIRRAVGWLEGVQNSDGGWGEDLRSYAYAKEWSGRGASTASQTAWALLALLAAGEKE
SKAVERGIEFLARTQNEDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPF
TGAEGS
>R9VYU1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAQAVFARGTAGVPSDDPRMQKAANWLLSKDVRHKGDWAMKVPNTQPGGWYFEFN
NEFYPDVDDTAQVLLALNKVDNPRERYQDQVARRAIDWEFAMQCRNGGWGSFDKDNSKMI
FQYVPFADHNAMLHPPTVDITGRMLEMLAAYGYTRDDKRVRKAIKFILDEQEPDGSWFGR
WGVNYIYGTFLVLRGLDAIGVCHNEPQMQHAAEWIRMVQNTDGGWGE
>A0A8J7M2S4|squalene-hopene cyclase|EC 5.4.99.17|Geomesophilobacter sediminis|TrEMBL
MTLPFKHPISSSLTSFNGAPVESEKESGNKHGATVHRLPASIWKSKQGKANSALDLAIER
SRDFFFREQLPKGYWWAELESNVTITAEYIMLFHFLGMVDREKQRKMANYLLSKQTENGS
WTIYFGGPGDLSTTVEAYFALKLSGYPAEHPAMEKARAFILEHGGIIKTRVFTKIFLALF
GEFAWFGVPSMPVELTLLPNWAYFNMYEFSSWARATIIPLSIVMEKRPVKKLPPAMRVQE
LFVRPPRPTDYTFTKEDGILTWKNFFIGVDHLLKIYESSPIRPFKKKALARAEQWVLEHQ
ETTGDWGGIQPAMLNAILSLATLGYPNDHPVIALGLEAMANFCIETDDELVLQSCVSPVW
DTALALKALVDSGVPADHPSLIKGAQWLMDKEVRKPGDWKVKAPTLEPGGWAFEFLNDWY
PDVDDSGFVMIALKGIQVKDRKSLDGAIKRGINWCLGMQSKNGGWGAFDKDNTKYLLNKI
PFADLEALIDPPTSDLTGRMLELMGTFGYAKTYPAAVRAIDFLKKEQEPEGPWWGRWGVN
YLYGTWSVLCGLSAIGEDPNQAYIRRAVNWIKSRQNIDGGWGETCESYHDRTLMGIGEST
ASQTSWALLALMAAGEAHCSTVARGIQYLLATQKEDGTWDEVNYTGTGFPKYFMIKYHIY
RNCFPLMALGTFREQTGGMLE
>A0A6P0SG21|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO2I5|TrEMBL
MQTQDRIVESGVTEAIANSQSYLLAQQYPDGYWWAELESNVTITAEIILLHKIWGTDKQR
PLHKAEAYLRSQQREHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDSALVRARDFILR
RGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPEWFPFTIYEMSSWARGSTVPLLI
VFDQKPVFDIQPSINLDELYTEGADHAKFELPRNSDWTDLFVLLDDGFKLAEDLNLVPFR
KQGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPVVQRGLEAIDRFAIE
TPDSYRVQACVSPVWDTAWVLRAMVESGLEPDHPALVRGGEWLLQQQILDYGDWVVKNPQ
GKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLKRAAIARGLAWIASMQCNQGGW
AAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEMLGSCNLSIESQQLEKAIAFLIQ
EQEADGSWFGRWGVNYIYGTSSALSALSKIAPHTHQRSIERGAAWLVKCQNLNGGWGETC
LSYDDPSLKGLGISTASQTAWALIGLIAAGEATGNWARDAIERGVNYLVSTQQPDGSWDE
TEFTGTGFPSHFYLKYHFYQQYFPLLALGRYQMSVSS
>A0A7Y7BBD1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces morookaense|TrEMBL
MTATTDGTGAHPPRAAEAGHSTIAEPLPAAAGAAKTHEAAERATARAVEHLLSRQDEQGW
WKGDLETNVTMDAEDLLLRQFLGIRDEETTRRAARWIRSQQRPDGTWATFHGGPAELSAT
VEAYVALRLAGDGPDAPHMAAASAWVRGQGGIAATRVFTRIWLALFGWWSWDDLPELPPE
IIYLPKWFPLNIYTFGCWARQTIVPLTIVAAHRPVRPAPFVLDELHTDPRRPNPPRPLAP
AASWDGFFQRLDKALHLYRRLPVGALRRSAVNSAARWIIERQENDGCWGGIQPPAVYSII
ALHLLGYDLDHPVLRAGLESLDRFAVPRENGEARMIEACQSPVWDTCLAAVALVDAGVAP
DHPALVKAADWMLDEQVLRSGDWTVRRPELPPGGWAFEFHNDNYPDIDDTAEVILALRRI
AHPDRERIGTAIRRAARWTLGMQSKNGAWGAFDADNTSKFPNRLPFCDFGEVVDPPSADV
TAHVVEMLSVLGKEHDPRTRRGITWLLAEQEPSGAWFGRWGVNYLYGTGSVVPALVAAGL
PVAHPAIRRAVDWLFSVQNPDGGWGEDLRSYRDPEWIGRGASTASQTAWALMALLAAGER
ESEAVARGVAWLADTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGEP
FAADRAREPRES
>A0A5B0BDA5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces apricus|TrEMBL
MTATTDGSTGALPPRAASASDIRTESTPLAAGTADTRDAAARAIQRATDFLLSTQDAEGW
WKGDLETNVTMDAEDLLLRQFLGIRDERTTRAAALFIRGEQREDGTWASFFGGPGELSTT
IEAYVALRLAGDAPQDPHMARAAAWIRGRGGIASARVFTRIWLALFGWWKWDDLPELPPE
LIWFPKWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHADPRDPNPVRPLAP
VASWDGAFQRLDRALHAYRKVAPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVI
ALHLLGYDLEHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPAD
HPQLVRAADWMLGEEIVRPGDWAVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVK
HHDPERVEKAIARGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVT
AHVVEMLAFEGLAHDPRTRRGVEWLLAEQEPNGSWFGRWGVNYVYGTGSVVPALVAAGLP
GSHPAIRRAVAWLETVQNDDGGWGEDLRSYHDAAEWSGRGASTASQTAWALLALLAAGER
HSTAVGRGIAWLAETQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEP
FAALPSSRSSFGRAS
>B9BLS8|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia multivorans CGD2|TrEMBL
MATLSAGTVPAELDAAVARATDALLAAQNADGHWVYELEADSTIPAEYVLLVHYLGETPN
LELEQKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQRARRAI
HAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWARTVIVPL
LVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRAVDHVLRAVDGLF
PAYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAIARKSIE
KLLVVHEDEAYCQPCLSPVWDTSLAAHALLETRDPRAEQAAVRGLDWLRPLQILDVRGDW
ISRRPHVRPGGWAFQYANPHYPDVDDTAVVAMAMDRAQKLNQSDTYRESIARAREWVVGM
QSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETALTSDAAR
RALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCALNAAGLGPDDARVKRAAQWLLSIQNK
DGGWGEDGDSYKLNYRGYEPAPSTASQTAWALLGLMAAGEVNNPAVKRGIDYLIAEQKEH
GLWDEARFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNTTRVTVGI
>A0A7W1JYB2|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MTSLDTAVERGAERLLSLQHPNGWWKGELESNATMTAQHLFLLHFLGLRDPETDRLLANE
LLAGRRGDGTWSIWFEGPADLSVTVEAYAALKLAGVDAGEATREYIRRAGGVPRARIFTR
GFLALIGQWPWNRLAHVPVELILLPAQGPLSVYDFACWARQTMVSLSVVEALRPVRPSAI
DLGEIGGRKTAPLGRPRHSRLRRHAIAVAERWVRERQEADGSWGGIQPPWVWSLIMLAAL
GHGFEDETFARGLAGWERFMVRDGDRLRPEACQSPIWDTALAILALRAAGLPADDPRLQA
AGRWLLDEEVKVRGDWAIRRPRLAPGGWSFEFDNDLYPDVDDTAVVLLALRELRLGEEAV
ERGLEWMVGMQSRSGGWGAFDVDNEARWLYKLPICDFGKVTDEPTADVSAHALEALAHEH
GYEASAESGLEWLLSEQEPDGSWFGRWGVNHVYGTGAAVPALEACGLPPEHPAIRRALAW
LDSVQQPNGAFGEDILSYSDPAARGRGAPTPSQTAWALLAYVSGGAATGLSTRRAAEYLC
ETQRGDGDWDERHFTGTGFPLDFMIRYHLYRLIFPLLALGRLRERLNG
>A0A538FRG4|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MTLAPDRTTTTLDLAIERATERLLELQHPDGWWVGELESNATMVAQHLFWHHFLGLRTPE
LDRKIANELLARRRDDGTWAIWFEGPPDLSTTIEAYTALKLAGVDPGTRAREYIRSEGGA
SRARVFTKCFLALLGHWPWQWIARLPPEVILLPPDGPFSVYNFSCWARQTVVPLSVVQAL
RPVRPAAIDLREIGARAGQTRPAPRPGPIRRVAFATAERWVRDRQEADGSWGGIQPPWVW
SIIMLAALGYGFEDETLRAAVEGWGGFTIDEGDRLRPEACQSPVWDTALAVLALLDAGVS
AGHPALRRAGDWLVREEVTVSGDWAIRKPDLPPGGWAFEFENDFYPDVDDTAVVALALRG
LGLGASAVERGLAWTAGMQSRSGGWGAFDVDNEAHWLYKLPFCDFGKVTDEPSADVSAHA
LEALAAEPRYAKEVERGLEWLLAEQEPDGSWFGRRGVNHIYGTGAALPALEACGLPSEHP
SMRRAVNWLQTVQQSDGSFGEDIRSYSDPSWRGRGQSTPSQTAWALLGYVAAGEAGSDPA
RSAADWLCFAQRSNGDWQEDHYTGTGFPLDFMIRYHLYRLHFPLMALGRLRERLAA
>A0A7K3GJC1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5789|TrEMBL
MTATTDGSTGAALKPLAPSASETDITVPAAAAGVPEAAARAVRRATDFLLSRQDAQGWWK
GDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGAWATFYGGPGDLSATIE
AYVALRLAGDDPDAPHMAKASEWVRGRGGIAASRVFTRIWLALFGWWKWDDLPELPPELI
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPALPNPPRPLAPAA
SWDGAFQRIDKVLHTYRKVAPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHP
QLVKAADWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVSHH
DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSSFPNRLPFCDFGEVIDPPSADVTAH
VVESLAVEGLAHDPRTRRGIQWLLAEQEQDGSWFGRWGVNYVYGTGSVVPALTAAGIPVS
HPAIRRAVTWLESVQNDDGGWGEDLRSYRYVKEWSGRGASTASQTAWALMALLAAGERES
GAVERGVAWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFA
EKPRPAPVAGRSADATSTAEVKGG
>A0A836TE04|squalene-hopene cyclase|EC 5.4.99.17|Nitrospinaceae bacterium|TrEMBL
MENMTKSQDEAPAPSQTGTDVRGEALDRSIERSRDFLLSRQDEEGYWVDELEGNVTISAE
LIFFMHFTDRLDPVKQDRIVKYLLHRQREDGSWPLFYGGLCDINSTVEAYMALKMAGLPA
DQKEMVRARQAIFANGGIKKTRVFTKMFLAMFGQVSWDDCPAVPAEIILLPNWFPFNIYE
ISSWSRGTVVPLSVVRSLEPVHELPEGRDVHELFTEKDVDLDFKPDGLPFTSWRNTFIYL
DRFIKTIGKFPWKPLRKKAFRKVEQWTLEHQEDEGDWGGIQPAMLNSLLALRLLGYANDH
PACVKGMEAVDRFLLEKDGRLWMQACVSPLWDTAIAANALLDSGLPSDHPALVKAGEWII
NKQVVKRGDWQVKNPGAEPGGWAFEFYNELYPDTDDTAEILLFLNRIEIADNRWKLSECQ
RAMNWLLSMQSKSGGWGAFDVDNDKEVLNEIPFADHKALLDPPTVDVTGRILWMLSKWGF
KKQHPQVQRAIQFIKERQEIDGCWFGRWGANYIYGTFLVLNGLCAIGEDMNAPFSRKAVR
WLEGHQNEDGGWGETCQSYQEPSLRGRGKSTASQTAWALLGLIAADEAENTAVERGVRYL
IETQKDSGDVSGSWWEDEFTATGFPIHFFIKYHMYQHFFPLMALSRYRRAAGGSEQ
>A0A853B7U7|squalene-hopene cyclase|EC 5.4.99.17|Amycolatopsis endophytica|TrEMBL
MTQTADPATRSGTGPAEVLDRAVAHLKGLQRDGGWWKGELQTNVTMDAEDLLMREFLGIR
TAAETEEAARWIRSQQRADGTWATFHGGPGDLSTTVEAWVALRLAGDSPDEPHLRRAAEF
IRRGGGVEASRVFTRIWLALFGLWSWDDLPNMPPELVLLPSWVPLNVYDWGCWARQTVVP
LTVVSTLRPVRPLPFGIDELRSGVRRGGGLVAPWTWSGAFQYLDKALHLYAKVPLKPVRE
FAMRQAAEWILARQEADGGWGGIQPPWVYSLLALHLLGYSLDHPAMREGIRGLDGFLIRE
ETPEGTVRRLEACQSPVWDTALAITALLDAGAPGDDPHLLKAADWMLGEEIAVRGDWAVR
RPDLDPGGWAFEFANDLYPDTDDTAEVVLGLRRVGHPDRERLGKALDRAVKWTTGMQSRD
GGWGAFDADNTRELTTKLPFCDFGAVIDPPSADVTAHVVEMLAKEGRADSRECRRGVKWL
LDHQEADGSWFGRWGANYVYGTGAVVPALAEAGVPVSSGAIRRAVRWLGEHQNDDGGWGE
DLRSYRDPSWSGRGESTASQTAWALLALIAAGERDSEVTARGVGWLAETQRADGTWDEPQ
FTGTGFPGDFYINYHLYRLVFPVTALGRYLGRS
>A0A5N9EJ11|squalene-hopene cyclase|EC 5.4.99.17|SAR202 cluster bacterium|TrEMBL
MVAQPKRTPVDQAADQAVRRSQEYFRRTQHPEGYWWGELESNPTMEAEYLMLCYFTGRHD
PERWRKVCNYILSKQRTDGSWGQYYEAPGDLSTSVECYFALKLAGHSPDSEPLRKAREFI
LSKGGMPKVRIFTKIWLALFGQWDWKGTPKMPPEMIFLPSWAPFNIYEFASWARATMVPM
LVILTRQPYCPVPESANIDELYPSGRDGTDYTLPKPTGGFGWAKGLYWSDKLVGLYQKLP
VHPLRGRAEQKIIRWVLKHQEADGSWAGIQPPWVYSLIALHTMGYGSEHEAVKKGFQGFE
TFALENEDKCNVQACISPVWDTCIAQLALVESGVAPDDPMVQSSARWLMDKQVFAGGDWQ
VRAKTVRPGGWSFEFDNQIYPDIDDASIVVMALDQVRLPEAEESRRADSILRGVEWMAGM
QSKNGGWAAFDKDNNKKYLTKIPFSDFGEILDPPSVDVTAHLLEMYGRLGYTREDAEVAR
GFEYVISEQEEDGSWFGRWGVNYVYGAGAVLPALEAIGEDMSQPYVRRAVDWVVAHQNED
GGWGESCGSYVDPTLRGVGPSTASQTAWALLGLVAAKEHESEATQRGLAYLAETQDADGS
WDEPYFTGAGFPGYGGGERLTEFPDIGETSYQGFDMPAGFMINYHLYRNYWPLLALGRYF
QAISGR
>A0A7K2F1J0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4921|TrEMBL
MTATTDGSTGAANLRAVPASDPTEPTIAPDDISAVARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPDTVKAAARFIRGEQMGDGTWNTFYEGPPDLSATIEAY
VALRLAGDRPDDPHMRRAAGWVREQGGIAESRVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPACPNPSKPAASAVSW
DGVFQRLDKALHLYHKVAPRKLRRSAMNAAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMRAGLESLDRFTVRREDGARMVEACQSPVWDTCLATIALADAGVSPDHPAL
VRAADWMLAEEIVRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARVEAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGRAQDPRTRRGIEWLLAEQEATGAWFGRWGVNYIYGTGSVVPALIAAGLPAAHP
AVRRAVDWLRSVQNDDGGWGEDLRSYREEKWIGHGASTASQTAWALLALLAAGERETRSV
ERGVAWLAETQQADGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFATAA
GADTGKGA
>A0A534BUC5|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MNRGSPTRGSFAVTPHAARADAPAHKIHRLAEFSPLDRTIAAARDALISLQSPQGYWLFE
LEADCTIPAEYVLMTHFLEEIDAPLEAKLAAYLRARQAEHGGWPLYHGGDFDMSCTVKAY
FALKLAGDSPQAPHMVRARAAILQRGGAARCNVFTRITLALFGQIPWRAVPYMPVEIVLL
PRWFPFHLDKVSYWSRTVMVPLLILCTRKPAARNPRNVQIRELFTTPPEEERHYFRRPGG
REGVLSRAFLALDRLGRMIDPLVPKAVRAYATRRAEAWMLERLNGEDGLGAIFPAMVNAL
EALAVLGYAASDARRLAAKRALEKLLVVDASSAYCQPCVSPVWDSALASLALQETGGAAA
LAASVRALDWLQPLQLLDKPGDWRVRRPQLAGGGWAFQFANAHYPDLDDTAVVAWSMHQA
GDPARYAHNIERALDWLVGMQSRNGGFASFDIDNTHYYLNEIPFADHGALLDPPTSDVTA
RVVTVLARVGRPQDQAALGRAIAFLRKEQEADGSWFGRWGTNYIYGTWSVLTAFAQAGIG
ADDPATRRAVSWLVARQNADGGWGESNDTYAYGQQAAGKSASAPHQSAWALLGLLAAGEV
GTDAVRRGVEYLLRTQQDDGLWSDPSFTAPGFPRVFYLRYHGYCAYFPLWALAAYRTLIR
LGTTH
>A0A8I0UF03|squalene-hopene cyclase|EC 5.4.99.17|Gluconobacter japonicus|TrEMBL
MSAPILKGMSNSLAHTVSCACDWLIGQQKGDGHWVGPVESNASMEAEWCLALWFLGLEDH
PLRPRLGNALLEMQRDDGSWGVYLDARSGDINATVEAYAALRSLGYSANNPVLLKASTWI
AEKGGLKNIRVFTRYWLALIGEWPWDKTPNLPPEVIWFPNNFVFSIYNFAQWARATLAPL
AILSARRPSRPLRPQDRLDALFPEGREKFDYTLPKKDRVDLWSSFFRTTDKGLHWLQSRF
LKRNTVREAAIRHMLEWIIRHQDADGGWGGIQPPWVYGLMALHGEGYPFHHPVLAKALAA
LDDPGWRYDKGEASWIQATNSPVWDTMLALMALHDANAQERFTPEMDKALDWLLNRQVRV
KGDWSIKLPDVEPGGWSFEYANDRYPDTDDTAVALIALSFCRHKEEWKRKGVDEAIDRAV
NWLIAMQSSCGGWGAFDKDNNKSLLSKIPFCDFGEALDPPSVDVTAHILEAFGLLGLSRD
LPVVQKALAYVRLEQDPQGPWFGRWGVNYLYGTGAVLPALAAIGEDMTQPYITKACDWLI
SCQQDDGGWGESCASYMDISSIGRGSTTASQTAWALMGLIAVGRPQDYEAIAKGCRFLID
RQEADGSWTEQEFTGTGFPGYGVGQTIKLDDPALSKRLMQGAELSRAFMLRYDMYRQYFP
IMALARANRLLSQDV
>A0A370X4C9|squalene-hopene cyclase|EC 5.4.99.17|Dyella psychrodurans|TrEMBL
MNSFTPIAESAVAEERLQPSATTSLDEAIERGRAALLAHQHKDGHWCFELESDCTITAEY
ILMMHYMDEIDDVLQEKMARYLRATQVKDGHGGWPQYYGGAIDLSCTIKGYYALKAAGDD
PAAEHMRIARDAILARGGAAKANVFTRILLALFEQVPWRATPYVPVEIMLLPRWFPFHID
KISYWARTTLVPLTVLCSLKAKAKNPRKINIRELFVTPPEQEHHYFVRGGLLNRTFLVLD
KIGRFADRFMPKAVRQRAVRKAEAWFLPRMNGEDGIGAIFPPMVNSYEAMELLGYPKDHP
ARQTCLRSIQKLVVHRDDGSAYCQPCVSPVWDTVWSALTLMNTSDDDATQSAVVKSVDWL
RSKQEMELKGDWAARKPDAVPGGWAFQYNNAYYPDIDDTAVAAALLHIQDRRRGESGRHR
INTDRAADWMIGLQSKNGGFAAFDADNTYYYLNAIPFADHGALLDPPTEDVSGRVAACLG
VLARPQDAESLRRCIDYLRSTQLGDGSWWGRWGSNYIYGTWSVLAGLALAGEDSRQPYIR
KSIEWLRSRQHADGGWGETNDSYIDPALRGSNHGVSTPQTTAWALLAQLAMGETHSDSVR
RGIAYLMANQQATGLWYHPSHNAPGFPRVYYLKYHGYTAYFPLWAMARYRQLSQSAAA
>A0A846HEI0|squalene-hopene cyclase|EC 5.4.99.17|Hassallia byssoidea VB512170|TrEMBL
MQTQHRVTVNQVTEAIAKSQNHLLSIQNPAGYWWAELESNVTITAEVVLLHKIWGTDSQR
PLHKVETYLRSQQRQHGGWELFYGDGGELSTSVEAYMALRLLGVSASDPAMRKARDFILQ
RGGISKTRIFTKFHLALIGCYKWRGLPSIPPAIMLLPDAFPFNIYEMSSWARSSTVPLLI
VFDDKPIYQVDSAIALNELYVEGADIQFELPRNNDWTDLFITLDNAFKLAENLNLMPLRS
EGIKAAEKWILERQEATGDWGGIIPAMLNSMLALKSLNYDVNDPIVVRGLQALDNFAIET
EDSYRIQPCVSPIWDTAWAIRALIESGLGADHPAIVKAGEFLLDKQILDYGDWAVKNHQG
KPGAWAFEFENRFYPDVDDSAVVVMALQIAKLPNEKLKQQAIARGINWIASMQCQAGGWA
AFDLNNNQDWLNLVPYGDLKAMIDPNTADVTARVLEMLGECKQSIDTQSFEKAIAYLINE
QEPDGSWFGRWGVNYIYGTSGVLSAFALVAPQTHQNSISRGATWLLKCQNPDGGWGETCR
SYNDPSLKGQGKSTASQTAWAIIGLIAAGQATGKIALPAIEKGINYLLATQQSDGTWDES
EFTGTGFPGHFYLKYHLYQQYFPLIALGRYQNL
>A0A7V8VMQ5|squalene-hopene cyclase|EC 5.4.99.17|Chthoniobacterales bacterium|TrEMBL
MAQSSSNVIPLPSASPDAARSYAPSLDDLREAISRAQENLLRQQHPDGHWCGELLVDSTL
CSDYVLFMHWLGDVEEALQQRCVRHILKRQLPDGGWNIYYGGPSEVNASVKAYFALKLAG
HSADLPFMQEARANILRLGGIPRMNTFSKLYLALLGQFPWQYLPSIPVEMILLPPWAPFN
IHKMSSWSRAMLVPLAIINHFKPTRELPGMQQLHELYPLGTEHKDFTLARDARLLTWRNF
FLRSDHALKIISKIGWRPMRQRALEEAERWMVERIGQGSDGLAAVFPAMLNALIALKALG
YPATHPVYQKTLADFRGLFVEDAEDFRIQPCLSPVWDSAINIIALAESGVPAEHPALRKA
AAWLVEKEVRIRGDWAVNNSHREGSGWAFEYNNVYYPDTDDTAMVLMGLRLVRPAEPEAL
DEVFKRALDWQLSFQCKDGGWAAFDKEVTQHWLEDMPFADHNAILDPTCS
>B7KXJ3|squalene-hopene cyclase|EC 5.4.99.17|Methylorubrum extorquens (strain CM4 / NCIMB 13688)|TrEMBL
MREAAVSKVETLQRPKTRDVSLDDVERGVQSATRALTEMTQADGHICFELEADATIPSEY
ILFHQFRGTEPRPGLEAKIGNYLRRTQSKVHGGWALVHDGPFDMSASVKAYFALKMIGDD
IEAPHMRAVRKAILQRGGAANANVFTRILLALYGEVPWAAVPVMPVEVMHLPKWFPFHLD
KVSYWARCTMVPLFVIQAKKPRAKNPRGVGVAELFVTPPDSVRTWPGSPHATWPWTPIFG
GIDRVLQKTQDHFPKVPRQRAIDKAVAWVSERLNGEDGLGAIFPAMVNSVLMYEVLGYPP
EHPQVKIALEAIEKLVAEKEDEAYVQPCLSPVWDTALNSHAMLEAGGHQAEANARAGLDW
LKPLQILDIKGDWAETKPNVRPGGWAFQYANPHYPDLDDTAVVVMAMDRAQRQHGLVSGM
PDYSESIARAREWVEGLQSADGGWAAFDADNNHHYLNHIPFSDHGALLDPPTADVTARVV
SMLSQLGETRATSRALDRGVTYLLNDQEKDGSWYGRWGMNFIYGTWSVLCALNTAGVDPQ
SPEIRKAVAWLIRIQNPDGGWGEDASSYKLNPEFEPGYSTASQTAWALLALMAAGEVDDP
AVARGVNYLVRTQGQDGLWSEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKRGNS
RQVQFGM
>A0A7C4XB58|squalene-hopene cyclase|EC 5.4.99.17|Proteobacteria bacterium|TrEMBL
MSTAVTTGIVESWQGTTYGYSASRAQAAPLWQGAPEAAELDEAIRRSRQYLLGLQHREGG
YWVGEVESNSTITSEYIYLMHFMGTVDELRQRKMVHYLQDTQLPDGGWNIYSGAPGDLST
TLEAYAAMKLAGESPDSRPMRLAREFALGHGGIENARVFTKIFFALLGAYPWQRCPALPP
ELMLLPVGFPLNIYEMSSWARATVVPLLILWHYKPVIRDGAGLDLEELRTCPEQGSGSGA
GQPAPVDRWGKMFLLSDRILKLYEKKPLAALRRKALRLAEQWILDRQDPSGDWGGIMPAM
MNSLMALKCLGYPLSHPSVRKGLEAVHRFAIEDARTLRLQSCVSPVWDTANTCLALLESG
LDGNNPALEKAREWLWTKQARVKGDWAVKNPKAEPGGWFFEFENRYYPDVDDTLAVLKVL
NQGCSRPDHAEAWHLGFQWLLSMQSRNGGWGAFDVDNDQEIWNRIPFADHKSMLDPPTSD
LTGRVLEFLGSAGYRNDFPAAQRGIAFLESQQEPDGSWFGRWGVNYLYGTWCALCGLKAI
GYPMDAPRVRRAVRWLKGCQNPDGGWGESCLSYDDPRYKGKGSSTASQTSWALMALVAAG
EAASEAAGRGAAFLVRTQNDRGSWDEEEFTGTGFPRFFYLRYHMYRDYFPLMALSRYRKA
RWQAGGQEGACR
>A0A6I4ZSF2|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
MRGRRREDLPRRERARARGSLVHGCRAHRADGGRIDTGQLDRRGGGATGRAGGGCVTAPS
SLQQDPARAGSGVDASGLDVCIDRSVKHLLSLQAEDGYWWAELESNATMAAEHLLLERFL
GTTEEEREQGIVRYLLGLQTEDGSWPVYWGGPGDVSITTEAYFALKLAGVDPERDEMKRA
REFIRDKGGVGATRIFTKLWLALFGQFEWSALPAMPPESILMPVSSPLNIYMFASWARAT
IVAILVVWAYRPVVPIPEYAHVDELYLDPMDRRSIPLRRDRQPFTWRNAFLAIDRVLHAH
ERLPWKPLRQYALKECERWIIEHQEADGTWGVIQPPSVYSLIALRAHGYSMDDPVMKKGL
NGFLGDFALRRGNTFSVQPCLSPVWDTALAVTGLREAGVPADDEALVQAGRWMLAHEVQS
LGDWALTVPGIEPGGFPFEFSNELYPDTDDTAEVLIALRLVDVRGKDGPFHRAKRWLRAM
QSTNGGWGAFDRDNNDEFVSRIPFADFGATFDPPTEDVTAHIVEAFALEGTPPSDEMIEQ
ALGYLWDTQEPDGSWWGRWGVNYLYGLG
>A0A5C7JJQ8|squalene-hopene cyclase|EC 5.4.99.17|Sphingomonadales bacterium|TrEMBL
MATASPLLREHFIAEQRDRLTALQKPDGHFVFELEADATIPAEYILLKHFLDERGGEAGL
AREQSIAVYLRRIQNPDGSWPLFHLGEGDISATIKAYWALKLIGEPIDAPHMAAARAWVL
ARGGAAKANVFTRFALALFGEVPWRAVPVMPVEIMLLPQWFFFHMSKVAYWSRTVIAPLL
VLYALKARAKNPTGQHIRELFIAPPEQHRPYNINPTGAAVGDAFLLLDKALRFLEPMFPK
GLRRKAIDAAVAFFTERLNGEDGLGAIYPAMANAVMAMDVLGFAKDDPRLVTAKHAIELL
VVERVEAHGPETYVQPCVSPIWDTGLAAHALLEASNDSVDPAVKRALDWLKDRQILEVKG
DWAVRRPNLRPGGWAFQYWNNHYPDVDDTAVVAIAMIRARDPAYDTAVARAAEWIIGMQS
SNGGWGAFDPENEHYYLNAIPFADHGALLDPPTADVTARCISFLAEFDPDRSDPIVQESI
RKAVEYLKREQEPDGSWFGRWGANYIYGTWSVLCALNAAGLGPEDGAVARAASWLAGQQR
DDGGWGEDLATYDPARKGEAKESTPSQTAWAVMGLMAAGQVDSAATARGVQWLEQAPRDG
ARWQEDLYTGTGFPRVFYLKYHGYAAYFPLWAVARYENLTKSNTRRVPHGM
>A0A521WYH0|squalene-hopene cyclase|EC 5.4.99.17|Methylobacter sp|TrEMBL
MFNEANSEINIGTISNSSNTANNFAHNLNQAINKAQEKLLSLQDKDGYWVFELEADCTIP
SEYIMMMHYLGEIDESLQAKIANYLRPRQSEDGSYPLFTGGAGDLSCSVKVYFALKMAGD
AVDAPHMTRLRNYILGQGGAAKANVFTRIALATFEQLPWRGVPYIPVEIMLFPNWFPFHL
DKVSYWSRTVMVPLFILCTLKATAKNPNNINILELFITHPDEEKHYFPERTLLNKIFLGL
DKLGLATRPLIPKKAHELAIKKAKDWFIERLNGEDGLGGIFPAMVGAYEAMLLLGMPADH
HHVVTARKAIDKLLVINEHDAYCQPCLSPVWDTALAALALQEADKISNSQSLTRAYDWLK
SKQLSDEPGDWRISKPDLAGGGWAFQFENPYYPDVDDTAVVAFAMAESSLPHLDESIHRA
TRWIVGMQSKNGGYGAFDVDNTYYYLNEIPFADHGALLDPPTSDVSARCAMLMARVAQDH
AEYLPALERTVEYIRSEQEQDGSWFGRWGTNYIYGTWSVLLGLEQTSLPKTDPLYTKAAK
WLKSVQRGDGGWGEDNYSYHDVSHSGKYHFSTAFQTAWAVLALMAAGEAHSHEVKAGIDF
ILRNQKTDGVWNDECFTAPGFPKVFYLKYHGYDKFFPLWALARYRNELNNK
>A0A514KNJ3|squalene-hopene cyclase|EC 5.4.99.17|Methylorubrum populi|TrEMBL
MREAAVSKVETLQRPKTRDVSLDDVERGVQNAARALTEMTQADGHICFELEADATIPSEY
ILFHQFRGTEPRPGLEAKIGNYLRRTQSKVHGGWALVHDGPFDMSATVKAYFALKMIGDD
IEAPHMRAARKAILQRGGAANANVFTRILLALYGEVPWAAVPVMPVEVMHLPKWFPFHLD
KVSYWARCTMVPLFVIQAKKPRAKNPRGIGVAELFVTPPDSVRTWPGSPHATWPWTPIFG
AIDRVLQKTQDHFPKVPRQRAIDKAVAWVSERLNGEDGLGAIFPSMVNSVLMYEVLGYPP
DHPQVKIALEAIEKLVAEKDDEAYVQPCLSPVWDTALTSHAMLETGGAAAEANARAGLDW
LKPLQILDIKGDWAETKPNVRPGGWAFQYANPHYPDLDDTAVVVMAMDRAQRQHGLVSGM
PDYSASIARAREWVEGLQSADGGWAAFDADNNHHYLNHIPFSDHGALLDPPTADVTARVV
SMLSQLGETRETSRALDRGVTYLLNDQEKDGSWYGRWGMNFIYGTWSVLCALNAAGVDPQ
SPEIRKAVAWLIRIQNPDGGWGEDASSYKLNPEFEPGYSTASQTAWALLALMAVGEVDDP
AVARGVNYLMRTQGQDGLWNEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKKGNS
RQVQFGM
>A0A833J652|squalene-hopene cyclase|EC 5.4.99.17|Methylorubrum populi|TrEMBL
MNDMTTASRQSNEARTMREAAVSKVETLQRPKTRDVSLDDVERGVQNAARALTEMTQADG
HICFELEADATIPSEYILFHQFRGTEPRPGLEAKIGNYLRRTQSKVHGGWALVHDGPFDM
SATVKAYFALKMIGDDIEAPHMRAARKAILQRGGAANANVFTRILLALYGEVPWAAVPVM
PVEVMHLPKWFPFHLDKVSYWARCTMVPLFVIQAKKPRAKNPRGIGVAELFVTPPDSVRT
WPGSPHATWPWTPIFGAIDRVLQKTQDHFPKVPRQRAIDKAVAWVSERLNGEDGLGAIFP
SMVNSVLMYEVLGYPPDHPQVKIALEAIEKLVAEKDDEAYVQPCLSPVWDTALTSHAMLE
TGGAAAEANARAGLDWLKPLQILDIKGDWAETKPNVRPGGWAFQYANPHYPDLDDTAVVV
MAMDRAQRQHGLVSGMPDYSASIARAREWVEGLQSADGGWAAFDADNNHHYLNHIPFSDH
GALLDPPTADVTARVVSMLSQLGETRETSRALDRGVTYLLNDQEKDGSWYGRWGMNFIYG
TWSVLCALNAAGVDPQSPEIRKAVAWLIRIQNPDGGWGEDASSYKLNPEFEPGYSTASQT
AWALLALMAVGEVDDPAVARGVNYLMRTQGQDGLWNEERYTATGFPRVFYLRYHGYPKFF
PLWAMARFRNLKKGNSRQVQFGM
>A0A7K3PPJ4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces coelicoflavus|TrEMBL
MTATTDGSTGASLRPLAASASDTDTDTDITIPAAAAGVPEAAARATRRATDFLLSKQDAQ
GWWKGDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELS
TTIEAYVALRLAGDSPDAPHMARAAEWIRSRGGIASARVFTRIWLALFGWWKWDDLPELP
PELIYFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPVRPNPPRPL
APAASWDGAFQRIDKALHAYRRVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYS
VIALYLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVP
EDHPQLVKASDWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRR
VRHHDPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSAD
VTAHVVEMLAVEGLAHDPRTRRGIQWLLDAQEADGSWFGRWGVNYVYGTGSVIPALTAAG
LPTSHPAIRRAVRWLESVQNEDGGWGEDLRSYRYVREWSGRGASTASQTGWALMALLAAG
ERDSKAVERGVAWLAATQREDGSWDEPYFTGTGFPWDFSINYNLYRQVFPLTALGRYVHG
EPFAKKPRAADAPAEAAPAEVKGS
>A0A7Y4LWH7|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium australiense|TrEMBL
MLSVDKKIAVDSVATVDPVALEKSISSATEALLGYRQSDGHFVFELEADSTIPAEYILLR
HYLAEPVDSALEAKIANYLRRTQGSHGGWPLVQDGPFDMSASVKSYFALKMIGDSVDAPH
MVRAREAIRSRGGASGSNVFTRFLLAFYGVLSWRAVPVLPVEIMLLPMWSPFHLNKISYW
ARTTIVPLMVMAALKPLAKNPKGVGIDELFLQDPKSVGMNKKAPHQSWGWFTLFSTLDKI
LRVAEPLFPKKLRQRAIDAALAFTEERLNGEDGMGAIYPPMANVVMMYDALGKGPDYPPR
AVTRKGIDKLLVIGEHEAYCQPCVSPVWDTALTCHALAEAGGDDTIKKMEQGLDWLKPRQ
VLDLKGDWAAKAPDVRPGGWAFQYNNDYYPDLDDTAVVVMAMDRARRASGSKEYDQAIAR
GREWIEGLQSRDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGET
AETSKAVADGIAFLRRTQLAEGSWYGRWGLNYIYGTWSVLCALNAAGVDHQDPMIRKAAD
WLLSIQNRDGGWGEDAVSYRLDYKGYERAPSTSSQTAWALLGLMAAGEVEHPAVVRGVEY
LKATQTEKGLWDEARYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNSRVVGVGM
>A0A6I4WN58|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura rayongensis|TrEMBL
MESFTEEERAERIADALDRAVAVLLSRQSDDGHWDGGLDNKVSVDAHHLLAHTFLGLPEP
PESREIRTWIRTQQTDEGGWPNFVGGPDELSTSVMAYLALRMGGEQAEAPHMRVAARRIH
QLGGPGACRASTRLWLALFGLWPWHDLKMLPPEIMLLPAKGPIALDDFADWARHLVVPLA
VITALRPVRRTGLDLGEICDRPPRSRFRARPVALYHASVPARIRRRSLLRARRWLLERQQ
TDGCWNGTHSATVYATIALHLLDGPGDREAVGRAVTGLGAFVRPRGDGLSRVQFSHGPIW
DTANTLLTLRAAGLGNDHPAVDRAHRWLLGQQTTAQGDWSRHRPELAPGGWSFQVANRTG
PDTDDTALVLRALDAASSSDEQTLQAADRGHRWLAGMAWSDGGWGAFDTDARVRRVLRLP
WHDARAVVDPPTADVTAHVVETLAAAGQEYAAPTRDGVRWLLDNQEPDGSWYGQWGCNYI
YGTTGALCALTAAKVPAAHPAVRQAIEWLYSRQNEDGGWGEDQRSYFYDVWHGRGRSTPS
QTGWAVHALITTGERGDRVKAGIDWLLRQQDASGAWHEAAYTGTGFPRDAPIRYGSYAQV
FATLALAGYRRPAADPGPAQASTPRQPTRDRRLRNGFRIAQPDRKR
>A0A089NXS0|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium oryzae CBMB20|TrEMBL
MNTEPRFSAPEILQSIAGAGRALLRRQRGDGHWVFELEADATIPAEYVLLEHYMDRITPD
RQAKIGVYLRRIQGEHGGWPMFHAGAFDLSASVKAYCALKAIGDDPQAPHMIRARQAILD
HGGAERANVFTRIQLTLFGAIPWRGVPVMPVEVMYLPKWFFFNIWAMSYWARACVVPLLV
LQALHPRARNPQGLSFDEIFRNSPEDICDWIRGPYRSRWGVAFKYIDTFLRVTEPVLSKI
ARGKAIAKAVAFVDERLNGEDGLGAIYPAMAYALMMYDVLGYPRDDPRCITIWKAIDKLL
VENEDEIYCQPCVSPVWDTSLSGHAMIEACRSGGVDAQKDLDAACDWLVARQVTEVRGDW
AETRPDLRPGGWAFQYRNDHYPDVDDTAVVAMLLHRNGRPEHAEAVEKARGWIVGMQSRN
GGWGAFDADNDREFLNHIPFSDHGALLDPPTADVTGRCVSLLAQLGREEDRPVIHRALTY
LRAEQEPDGSWYGRWGTNYIYGTWSVLCALNAAGVPHDDAMVRRAVDWLISIQRADGGWG
EDERSYDVGRYVENAESLPSQTAWAMLGLMAAGQADHPAVSKGAAYLQSSQGAQGEWQER
AYNAVGFPRVFYLKYHGYRLFFPLFALSRFHNLKRGNSRQVNFGF
>A0A098GBW4|squalene-hopene cyclase|EC 5.4.99.17|Legionella fallonii LLAP-10|TrEMBL
MIEPKRNILDIVIKRATDYALGIQHQEGYWIAPLDSNSTMEAEFLLLLYFLGIHDEVRQQ
KIVNHILKHQQEDGSWSLYFQGSGDLSTTVECYFALMLSGVSKDAPNMKLAREFIIAKGG
IAKVRVFTQIWLALFGQWSWQQIPTLLPEIIFLPSWFPFNVYAFASWARATVVPLTIVMA
ERPVCAIPNHCALTDLFLQDAMPQKAQGHGIWGVIFKVIEKGFKLYERMPWKPGRRLAIK
KSIQWIIDHQEADGSWGGIQPPWVYSLIALKLTGHSLEHPVMRKGIDGFDSFSIEDNETM
QVQACVSPVWDTSLMINALKEVGVESSHPQIQSACRWLIKKQILVGGDWSIQNPKLSPGG
WAFEFENANYPDIDDTAEVLMALWHASLSESENVQCKVAIKTGTQWLLGMQGKNGGWAAF
DRENNNFFLAKFPFFDFGEILDPPSVDVTAHVLEALGMMGYTRDNPVIKRALDYIYQEQE
PNGSWFGRWGVNYIYGIGTVLPALRAVGEDITSPTIQKAIQWLLAHQNADGGWGESCASY
VDVTQHGCGPSTPSQTAWALLALMAVDQYEHPAVHKGIDYLCDTMNVQGTWDEDHYTGCG
FPGYGEGQRKSIASLQEGHLKDAIASAGFMINYNLYRHCWPLMALGRYQKGWFGNK
>A0A7Y6PRL0|squalene-hopene cyclase|EC 5.4.99.17|Kofleriaceae bacterium|TrEMBL
MVEPEINEARANADLVIARAHDRFRREQFADGYWWAELESNATMDAEYILMTHVIGERND
AIWRGVAQDIRSYQRDDGSWALYEGAPGDLSTTIECYFALKLAGDEGPHLDRARDFAIAR
GGIGRARVFTRIWLAICGEWSWDDLPTMPLELMLLPARAPFSIYTFGSWARATVVPLLLL
MNDRPVRPVPASARLSALKMPAPPIQPRDTVDRVFFAIDALLRRYHRLPWHPLRKHAREA
AEQWVVDHQEADGSWGGIQPPTVYSLMALHALGYGSDHPVIRKGIDGMHDRWMIRRADGS
KRIQACLSPVWDTALSLVALLESGVARTEPMVESAATWLRKEEVRVPGDWCVRVPEVEPS
GWSFEFENDLYPDIDDTAVVLLGLHRAGALDDETRNRAVKWLLAMQSKSGGWAAFDKDNT
SRLPAMIPFADFGEMIDPPSADVTGHVVETLAVLGFDRGHPAMIKALDYLYREQEPEGSW
FGRWGVNHIYGTGAVLPALAAIGEPIDSVPVRRAIRWLVERQNHDGGFGEGCESYVEVAA
RGRGPSTPSQTAWALLAFIAADRADSPAARRAAEYLIDTQRAEGRWDEDAYTGCGFPGYG
VGEQRGARIREGRELCAGFMLRYHMYRDCFPLLALGRYRAAVRRRGGVV
>A0A845WPY1|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO4G3|TrEMBL
MQIQDRIVHSGVTEAIANSQSYLLAQQYPDGYWWAELESNVTITAEIILLHKIWGTDKQR
PLHKAEAYLRSQQRKHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDSALVRARDFILR
RGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPQWFPFTIYEMSSWARGSTVPLLI
VFDQKPVFDIQPSINLDELYTEGADHAKFELPRNSDWTDLFVLLDDGFKLAEDLNLVPFR
KQGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPVVQRGLEAVDRFAIE
TPDSYRVQACVSPVWDTAWVLRAMVESGLEPDHPALVRGGEWLLEQQILDYGDWVVKNPQ
GKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLKQAAMARGLAWIASMQCNQGGW
AAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEMLGSCNLSIESQQLEKAIAFLIQ
EQEADGSWFGRWGVNYIYGTSSALSALSKIAPHTHQRSIERGAAWLVKCQNLNGGWGETC
LSYDDPSLKGLGISTASQTAWALIGLMAAGEATGNWATDAIEGGVNYLVSTQQPDGSWDE
TEFTGTGFPSHFYLKYHFYQQYFPLLALGRYQMSVAS
>A0A7H4Q6X7|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia sp|TrEMBL
MNDLSQIPPTDGETPASIPASTFAATADTAVPHDMLESAIARATDAILADQRADGHWVYE
LEADATIPAEYILLVHYLGEEANPTLEQKIGRYLRRIQLADGGWPLFTDGALDVSASVKA
YFALKMIGDPEDAPHMRRAREAILAHGGAEASNVFTRILLALFGVVTWYAVPMMPVEITL
LPKWFPFHLSKVSYWARTVIVPLLVLNAKRPVARNPRGVRIDELFRGAPVTTGLSPRAPH
QHKGWFSFFRAVDGVLRTIDGLFPRTLRQRAVQAAVAFVDERLNGEDGLGAIFPAMANAV
MMYDVLGYPADHPSRAIARRSIEKLLVIHEDEAYCQPCLSPVWDTSLAAHALLETGDTRA
EEAAVRGLEWLRPLQILDVRGDWISRRADVRPGGWAFQYANPHYPDVDDTAVVAMAMHRA
AALTQSNVDNTAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTAD
VSGRCLSMLAQLGEMPSTSEPSKRAYDYILKEQASDGSWYGRWGMNYIYGTWTALCALNA
AGIQHDDVRIARAVQWLVKIQNEDGGWGEDGTSYKLEYRGYEQAPSTASQTAWALMGLMA
AGAIDHPAVARGIEYLQREQRDHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYR
SLRCSGGTRVTVGM
>B1LYI9|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 / 0-1)|TrEMBL
MREAVSKVEALQRSKTQGISLEDVERGVAQATRALTALAHDDGHICFELEADATIPSEYI
LFHHFRGTQVPGDLEAKIGNYLRRTQGRHGGWALVHEGPFDMSCTVKAYFALKMIGDDIE
APHMRRAREGILSRGGAANANVFTRFMLALYGEVPWRAVPVMPVEVMFLPKWFPFHLDKI
SYWARTTVVPLFVLQATKPRARNPRGISVQELFVTPPESVRSWPGSPHATWPWTPIFGFI
DRVLQRVENHLPRKSRQRAMEMARAWVSERLNGEDGLGAIFPAMVNSVLMYEVMGYRPDH
PQVRVACDAIEKLVVEKADEAYVQPCVSPVWDTALASHALLEAGGPEAEAQARAGLDWLK
PRQVLDIVGDWAARKPKVRPGGWAFQYANAHYPDLDDTAVVVMAMDRAMHQHGLVAGMPD
YKASIARAREWVEGLQSEDGGWAAFDADNNHMYLNHIPFSDHGALLDPPTADVTARVVGM
LSQLGETRETSRALDRGVNYLLNDQEEDGSWYGRWGMNFIYGTWSVLCALNAAGVDPADP
RIQKAVSWLIRIQNPDGGWGEDASSYKIDPAFEPGSSTASQTAWALLALMAAGAVDDPAV
TRGINFLTRTQGADGFWKEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKRGNSRR
VQFGM
>A0A7X1IYW5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. PSKA01|TrEMBL
MTATTDGSTGALPPRAAAASETDSTTPAAAGVHDAAERALRRATDFLLSRQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDESTTRAAALFIRGEQRADGTWGTFYGGPGELSTTIEAY
VALRLAGDTPDAPHMAKAAEWIRAQGGIAAARVFTRIWLALFGWWKWEDLPELPPELIYF
PTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPANPNPPKPLAPAASW
DGAFQRLDKALHQLRKVAPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLEHPVLREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHPQL
VKAADWMLGEEIVRPGDWAVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHEP
ERVERAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIQWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALTAAGIPASHP
AIRRAVNWLESVQNDDGGWGEDLRSYKDVKGWSGRGASTASQTAWALMALLAAGEKDSKA
VQCGVEWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFAEA
EGG
>A0A367EBN7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces reniochalinae|TrEMBL
MTATTDGPAGPGVSGTKNTARVAPPAAPAAQESVTALAERTAARAVDHLLARQDEAGWWK
GDLDTNVTMDAEDLLLREFLGIRDETTYAAAARWIRSQQREDGTWATFHGGPGDLSTTIE
AYVALKLAGDATEAPHMTRAAAWVREKGGVARSRVFTRIWLALFGWWRWEDLPEMPPEII
YFPKWFPLNIYDFGCWARQTIVPLTVVCAFRPVHPAPFALDELHRDPAHPRPDAKMAPAT
TWDGAFQRIDRALHAYRKVASRRLRRAALREASRWIIERQENDGCWGGIQPPAVYSVIAL
RLLGYDLDHPVLKAGLESLDRFAVWPDADTRMVEACQSPVWDTCLASIALADAGLPRDHP
ALVRAADWMLGEQVVRPGDWSVRRPGLTPGGWAFEFHNDTYPDTDDTAEVALALRRIQHP
DPERVERALARAVRWNLGMQSRDGAWGAFDVDNTSKFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAAEGKQHDPRTRKALAWLLSEQEADGCWFGRWGVNYLYGTGSVVPALVAAGLPAS
HPAIRRAVRWLEKVQNEDGGWGEDLRSYIDSEWVANGTSTASQTGWALMALLAAGEKDSK
AVERGVGWLAETQREDGYWDEPYFTGTGFPWDFSINYHLYRMVFPLTALGRYLHGDGLER
LARRVA
>A0A4R1CV24|squalene-hopene cyclase|EC 5.4.99.17|Frankia sp. BMG5.11|TrEMBL
MSLTSDQSSAAPTAAAQSPKIPNPSVARPSVDAGSFETAGAVRTDSLSIDSVSTGTVSTG
TPVDPVVGAMRRGRDHLLSLQAEEGWWKGELETNVTMDAEDLMLRQFLGILTPSTATETG
RWIRSQQLSDGGWATFYGGPSDLSTTIEAYVALRLAGDDPDAPHMRSAAEWVRSAGGIAA
SRVFTRIWLALFGEWSWDDVPVLPAEMTFLPPWFPLNIYDFACWARQTVVALTIVGSLRP
VRSFGFTLDELRVPAPKAARAPLRSWAGAFERLDSVLHRYEKRPFQPLRRLALRRAAEWV
IARQEADGCWGGIQPPMVYSIMALHLMGYPLNHPVISMAFRALDRFTIREETPEGTVRRI
EACQSPVWDTALAVVALADAGLGGDHPAMVRAGRWLADEEVRVAGDWAVRRPTLAPGGWA
FEFDNDFYPDVDDTAEVVIAIRRLLGDGHGPVDHSDGSGPGSAADPELAARLRAAAERGV
DWSVGMRSSNGAWAAFDADNVRTLVTKIPFCDFGEVVDPPSADVTAHMVEMLALLGRSDH
PITQRGVRWLLDNQEAGGSWFGRWGVNHVYGTGAVVPALISAGVSAEHPAIVSSMHWLVE
HQTPEGGWGEDLRSYRDDEWIGRGEPTASQTAWALLALLAAEPASGTAEWEAVERGVRWL
CDTQRPDGTWDEPQFTGTGFPWDFSINYHLYRLVFPVTALGRYVTLTGRSTS
>A0A549SLX7|squalene-hopene cyclase|EC 5.4.99.17|Methylosinus sporium|TrEMBL
MTAALAIEPKRDDALDQSIARASGALRALAKGDGHWCFELEADATIPAEYVLMRHFRDEP
IDHALEGKIAVYLRRIQGAHGGWPLFHEGAFDMSASVKAYFALKMIGDDRDAPHMKQARE
AILAHGGAARSNVFTRALLALYGEIPWRGVPAMPVEIMLLPKWFPFHIDKISYWGRTVLV
PLLVLQTLKPQAVNRLGVHIGELFATPPNEVKKWPTGAHQHPALVAMFGAIDRLLRAAEP
LFPKGPRRRAIKAAEAFVTERLNGVDGLGAIFPAMVNSLLMYDVLGVPADDERVRLARES
IERLLVIKEDEAYCQPCVSPVWDTALACHTLLEVGGEEEEARARAGLDWLAPLQVLDVKG
DWAVQRPNVRPGGWAFQYANAYYPDVDDTAVVVTAMDRSYAGRSDRPYDERIARAREWVE
GLQSKNGGWGAFDADNEYYYLNHIPFADHGALLDPPTSDVSARCVSMLAQLGDTIETSPR
MKAGVDYLLAEQEPDGSWFGRWGMNYIYGTWSTLCALNAAGLKPEHRAMRRAVDWLVAIQ
NEDGGWGEDGDSYKLDYRGYEKAPSTASQTAWGVLALMAAGEVGHPAVARGVAYLQANQD
KEGLWKEERFTATGFPRVFYLRYHGYAKFFPLWALARYRNLERGNSKIVQTGL
>Q1LF08|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)|TrEMBL
MTRKTIPASELDAAIVRARDALLDRQHPDGHWCFELECDATITAEYILMMHFVDEIDTAL
QARMAKYLRAVQRLDGHGAWDLYFGGDLDISCSVKAYFALKAAGDPPDAPHMVRAREAIL
ARGGAAKSNVFTRILLATFGEIPWRGTPFMPVEFVLFPRWAPIHMDKVAYWARTTMVPLL
VLCSIRAAAKNPLGVHVQELFVTPPELEREYFPRKRGLQQAFLVADRVVRHLEPLIPRAL
RRRAIQRAVEWSEARMNGEDGFGGIFPPMVYSYEMMVLLDYPEDHPLRVECKAALKKLVV
HRDDGSSYCQPCLSPVWDTAWSVMALEQAPSDARTETAIARAYDWLTDRQVLDLRGDWEN
NAAPSTPPGGWAFQYENPYYPDIDDSAVVLAMLHARGKRTGQPGRYEMPVARCLDWIIGL
QSRNGGFGAFDANCDRDFLNAIPFADHGALLDPPTEDVSGRVLLALGITERPQDATARER
CIQYLRDTQQPDGSWWGRWGTNYIYGTWSVLAGLGLAGVDRKLPMVRNGLQWLRGKQNAD
GGWGETNDSYARPELAGKHEDGSMAEQTAWAMLGQMAVGEGDADSVHRGAAYLLDAQNED
GFWMHPYHNAPGFPRIFHLKYHGYTAYFPLWALGRYRRLAAARASAMQTAKAESAESMTA
H
>A0A8J7YXA9|squalene-hopene cyclase|EC 5.4.99.17|Myxacorys almedinensis A|TrEMBL
MQLENRAEISLLERAINASQTYLLSIQKPEGHWWAELESNVTMTAEAVLLHKIWGTDQSR
PLDKAEKYLRSQQRDHGGWELWYGDGGDLNVTVETYMALRLLGVPAHDPALLRAKEVILS
RGGITQTRIFTKFHLALIGCYDWRGLPSIPPWLMLLPSLKVELPNPFGSEPFFSGHSFSI
YEMSSWARGSTVPLLVVFDRKPVFITSPTITLDELYVEGIAHANYELPSNSDWSDVFLSL
DKAFKVAEDWNLVPFREAGLNAAEQWILERQEPTGDWGGIIPAMLNSMLALRCLGYDAAD
PIVERGLHAIDNFALETDDTYRMQACVSPVWDTALVMRSLVESGMAADHPALTKAGQWLL
DRQILDYGDWAVKNTVGKPGGWAFEFDNRFYPDVDDTAVVVMALANLAMPNPRSTEQAIK
RAVEWISTMQCKPGGWAAFDLDNDQDWINAVPYGDLKAMIDPNTADVTARVLEMLGRLET
ASLDPSLVAGLSPAQTERALTYLARAQEPDGSWFGRWGVNYIYGTSGALSALAIVAPTTH
RQAIYRGATWLVQCQNPDGGWGETCESYKNPALKGKGESTASQTAWAVSGLLAAAEALGE
SVWGAIDRGVEWLIKTQGDNGAWREDYFTGTGFPGHFYLKYHLYFQHFPLTALGRYQTAK
AKSRVNQ
>A0A6G6Z8W3|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. 6(2017)|TrEMBL
MLSRDHSVAVDPVALEKSISKATEALLGYRQSDGHWVFELEADSTIPAEYVLLRHYLAEP
VDAGLEAKIANYLRRTQGAHGGWPLVHDGPFDMSASVKSYFALKMIGDSVDAPHMVRARE
AIRSRGGASGSNVFTRFLLALYGVVTWRATPVLPIEIMLLPMWSPFHINKISYWARTTMV
PLMVLAALKPRAKNPKGVGIDELFLEDPKSVRMAPKAPHQSAGWFYLFRSLDAVLRAIEP
MFPKRLRRRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYEALGMDENFPPRAITRRG
IDKLLVIGDDEAYCQPCVSPVWDTALACHALQEAGGDDTLAKAKQGLDWLKPRQVLELKG
DWAVKAPDVRPGGWAFQYNNDHYPDLDDTAVVVMAMDRVRRQSGTREYDEAIARGREWIE
GLQSRDGGWAAFDANNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLGQLGETAKNSKA
MADGIAYLRRTQLPEGSWYGRWGLNYVYGTWSVLSALNVAGIDRNDPMIRNAVDWLASVQ
NQDGGWGEDAVSYRLDYKGYEAAPSTSSQTAWALLGLMAAGEVENPAIARGVEYLKATQT
EKGLWDEQRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNSRVVGVGM
>Q39BM5|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MNDLTEMATLSAGAVPAGVDTAVARATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPNYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANSVMMYDVLGYAEDHPNRAI
ARKSIEKLLVVQEDEAYCQPCLSPVWDTSLAANALLETRDARAEDAAIRGLEWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAVAMERAQQLKQNDAYRDSIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRVKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGIDYLI
AEQNAEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNTTRVTVGL
>S0EVH8|squalene-hopene cyclase|EC 5.4.99.17|Chthonomonas calidirosea (strain DSM 23976 / ICMP 18418 / T49)|TrEMBL
MKTRLDHAETESVQAIVPSAARTHSVLNGHLTSTISLEAIRQALRGAIHYLRDRQQPDGH
WVAELEGDTILESEYILLLQFLGKNDPEKFRKLANYIRSKQHPEGYWAIYPGGPPEVSAS
VKAYFACKLAGFSESEPFMIRARRAILSLGGVTHCNTFTKLYLSIFGQYDWYGVPVIPPE
LILMPKWFYFNIYEMSSWSRAILVPLSVINALRPYRPIPAHATIDELFVGGKSRKRMRLP
WDSRPLTWRNVFLIVDKILKLYHASPIKPFRKLALQRCLQWLLEREENSGGLGAIFPAMT
HAIMAYKCMGLPDDHPAIQKELKELAAFEIEEGDTIRLQPCVSPVWDTAISLNALLDSGY
PPESEEIRKAAEWLLSKQTRKKGDWAVKVRNVEPGGWYFENENEFYPDVDDTIMVLMALY
KTYCHDGRPWTEAPPEVREAMRKGLNWVFAMQNRDGGWASFDKDNNRILFQYVPYADHNA
MLDPSSADITARVLEMCSYYGIGKTDPRVKRAIAYLYKEQEEDGSWFGRWGVNYLYGTWQ
VLRGLSRIGEDMRSERIQRAVRWLHSVQNEDGGWGESCQSYEPGHPKATGPSTPSQTAWA
LMGLFNAGDLSSCAVQRGIEYLLKNQTDDGTWLEEWFTGTGFPRVFYLRYHFYRHYFPLW
ALAQYHRFVTGEPAYTPELAQPSTDRFANLEV
>A0A7K1KW16|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura litoris|TrEMBL
MTTTAEPAAPSTREAARKTLDAAREHLLGLQSPEGWWKGELQTNVTMDAEDLLLREFLGV
RDEEETREAARWIRSQQREDGTWANFFGGPPDLSTTVEAYVALRLAGDPTGADHMRRAAA
YVREAGGLPATRVFTRYWLALFGRWPWDALPVVPPEMIYLPSWFPLNVYDFGCWARQTIV
PLTVAAALRPVRPLPFDIAELHGQHVRRRRQGPPGWAEAFHALDRALRVYQRRPVKAVRR
AALRRAAEWIIARQEPDGSWGGIQPPWVYSLIALNLLGHDVDHPVMRRGLQGLERFTIRD
GQGRRLEACQSPVWDTALAMTALADAGMPAGHPALEKAAAWVVGEEVKGPGDWQVRRPGL
PPGGWSFEFDNDYYPDVDDTAEVVLALGRVAHPDAPPAVERGLRWMAGMVSRDDGFGAFD
ADNTRELCRRLPFCDFGEVIDPPSADVTAHVVEALCAQGMGDSQLCKRAVVWLLKAQEQD
GSWYGRWGANHVYGTGAVVPALIAAGVRPGKPVIRRAVAWLERHQRDDGGWGEDLRSYRD
PAWIGRGASTPSQTAWALLALLAAGERGPAVERGVGWLTERQRPDGTWDEDHFTGTGFPG
YFYINYHLYRLVFPVSALGRYLREDAS
>K9ZMR9|squalene-hopene cyclase|EC 5.4.99.17|Anabaena cylindrica (strain ATCC 27899 / PCC 7122)|TrEMBL
MQTQNRVQVKQIAEAIKASQKHLLAIQKPDGYWWAELESNVTITAEAVLLHKIWGTDKTR
PLHKVETYLRSQQREHGGWELFYGDGGELSTTVEAYMALRLLGVPANDPALIKAKSWILE
KGGISKTRIFTKLHLALIGCYNWRGLPSLPSWVMLLPDNFPFNIYELSSWARSSTVPLLI
VFDRKPIFKIDQPINLDELYTEGVKNVKWELPKNGDWSDIFNILDNGFKLAESFNFVPFR
NEGIKAAEKWILERQEATGDWGGIIPAMLNSLLALKCLDYDANDPIIYRGLKAVDNFAIE
TENSYCVQPCVSPVWDTAWAIRALIDSGFPADDPAIIKAGEWLLEKQILDYGDWSVKNKQ
GKPGAWAFEFDNRFYPDVDDSAVVVMALHQTKLPNEELKKQAINRALNWIASMQCQPGGW
AAFDIDNNQDWLNSVPYGDLKAMIDPNTADVTARVLEMLGACNLSIPSDKLEKSLDYLLN
EQEKEGCWFGRWGVNYIYGTSGVLSALALINPQKYRSEIEQGAAWLVKVQNSDGGWGETC
FSYNDPSLKGKGDSTASQTAWGLIGLIAAGEATVKIPFDSIERGINYLLETQRSDGTWDE
SYFTGTGFPCHFYLKYHLYQQYFPLIALGRYQGIKG
>A0A6G4AWZ1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces rhizosphaericus|TrEMBL
MTATPTVQPSESSEPKTLSVAREATARAVDHLLSRQDERGWWKGDLETNVTMDAEDLMLR
QFLGIQDPDTLDAAARYLRSQQATDGTWATFHGGPPELSATIEAYVALRLAGDEPDAPHM
AAASAWVRSRGGIASSRVFTRIWLALFGWWRWEDLPELPPEIIYFPKWLPLNIYDFGCWA
RQTIVPLTIVSAKRPVRPAPFPLDELHTDPRRPNPPRPLAPVASWDGVFQRLDRALHAYH
KVAFRPLRRAALRSCARWIVERQENDGCWGGIQPPAVYSLIALHLLGYDLDHPVMRAGLE
SLDRFAVWREDGSRMIEACQSPVWDTCLAAIALADAGLAPDHPALVKAADWMLTEQIDRP
GDWSVRRPGLPSGGWAFEFHNDNYPDIDDTAEVILALRRVDHPEPERIEAAVRRAMRWTL
GMQSKNGAWGAFDVDNTSPLPNKLPFCDFGEVIDPPSADVTAHVVEMLAHEGRTYDARTR
RGISWLLAEQEPSGAWFGRWGTNYVYGTGSVVPALIAAGVPASHPAVRRAVRWLESVQNE
DGGWGEDQRSYLDAEWMGRGASTASQTAWALLALLAAGERDGAAVERAITWLVRTQRQDG
SWDEPYFTGTGFPWDFSINYHLYRQVFPVTALGRYVHGEPTGARPRSG
>A0A0E3P2Z6|squalene-hopene cyclase|EC 5.4.99.17|Methanosarcina siciliae T4/M|TrEMBL
MSNRTLNDKISDNRTLNDKISGNKIFDNRMLKAVELAIRKASNFIISNQSGEGYWLDFYI
PGMGNSSQWVTAYIAYNLSRLPNTDESVQKAIVWLLHTKSSSGWGYHQNCLPDADSTANV
VRLLAYYFKKENLLTQENFAFYLHEFADLLASYQDKNTGGFLTYLPGSNGRYHTMPDSAW
CISEPSITAMTGNAFLNSGPERFEQEISNAREFLISRQNPAGYWDSYWWDCRIYGTSLAC
SFLKQLGEIDPVKKAISWLESVFVPSKGWGNGYEADPYPFYTALSLSSLLLFENNIHSRE
VKDSVLWLIGNQKEDGSWFSKPILRVPDPQVREPWAGSNRRKCEVVTDVNLLFTTATVMG
VLYDFLNLSGYYSCSASQE
>A0A537UJV7|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MNCVQPKSSAVDQSIEAATRGLFALQQPDGHWVFELEADATIPAEYILLRHYLAEPVDNV
LEAKIAAYLRRVQGEHGGWPLFHEGAFDMSASVKAYFALKMIGDSVDAPHMARARAAIRA
RGGASRSNVFTRVMLALFGFIGWRAVPVMPVEIMLLPKWFPFHLEKVSYWSRTVIVPLLV
LMALQPRARNPRRVALDELFLELPQTIGLAPKAPQQKAAWFWVFRAVDTVLRFAAPRFPR
PLRQRAMQCAVSWVTERLNGEHGLGAIFPAMANSVMMFDALGYADGHPHRAIARRSIEKL
LALRDHEAYCQPCVSPVWDTALACHSLLEVGSDQAVTQVRKGLEWLAAKQILELKGDWIA
RRPDVRPGGWAFQYANPHYPDVDDTAVVVMAMDRAQRLSSQNDFRASIAAAHEWVLGMQS
NNGAWGAFDADNEHYYLNNIPFADHGALLDPPTEDVTARCISMLAQIDESAPNSAAVARA
VDYLRRTQTAEGSWYGRWGMNYIYGTWSVLCALNAAGVDHASPELRRAAAWLVKIQNSDG
GWGEDGMSYRLDYRGHESAPSTASQTAWALLGLMAAGENDHPAVARGIDYLLRTQGEDGF
WNEPRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLKNTNARSVPHGI
>D8JS39|squalene-hopene cyclase|EC 5.4.99.17|Hyphomicrobium denitrificans (strain ATCC 51888 / DSM 1869 / NCIMB 11706 / TK 0415)|TrEMBL
MTTNAAATSARSGEDAIRQVSGQQLETAIASARNSLLALQRPDGHFVFELEADATIPAEY
VLMRHYLAEPVDAVLEEKIARYLRRIQSDDGGWPLFRDGASNISASVKAYYALKMIGDAP
NAPHMQKARAWILAQGGASHSNVFTRNLLALFGAIPWSGVPVMPVEIMLLPKWFPFHIDK
ISYWARTVLIPLTVLNALKPVARNPKGVGIAELFVTPPDQVRNWPKGPHQKFPWSQVFGG
IDRVLRLFEPAFPKSLRKKSIDKAVAFATERLNGEDGLGGIFPAMVNALLVYDALGYPHD
HPDYVTARGSIEKLLVIKDDEAYCQPCLSPVWDTALAVHALMESGVAQADQNVDRALAWL
KPLQVLDTVGDWAASRPGVRPGGWAFQYANAYYPDVDDTAVVVMAMDRAAGGDAAKRDHY
RESMARGREWVAGVQSKNGGWGAFDADNTYEYLNQIPFSDHGALLDPPTADVSARCVSML
AQLGERRETSPVLDKAMRYLESTQEKDGSWYGRWGMNYIYGTWSVLCALNAAGVAPSAPS
MRKAADWLLSIQNSDGGWGEDGESYSLDYKGYEPAPSTASQTAWALMGLMAAGEVDHPAV
QRGVAYLAAKQGSDGFWGEERFTATGFPRVFYLRYHGYSKFFPLWALARYRNLNAANSKS
VLVGM
>A0A7W9X5C6|squalene-hopene cyclase|EC 5.4.99.17|Mucilaginibacter sp. X5P1|TrEMBL
MFDTTASIFAAASFSQTPKIDLPEIKNPWQALSYKGLEHLLQEYANGFSATKHVMPFPRE
VFQVDKDFQEGDVFQRALILDTLLDFNPGMQNQLDDIISAEADYLFNARRKTGIGGWAYF
PELRELPPDADDLAQVMQVLLRAGYSKTATPYFELALNVLLNDQTNADNGWESWIIPKNN
QTEEQQLQTIWVNKAWGTGSDIEVVANLIYAFILFDNKRFAAAIERGLTFLLNSHKNSHC
WESTWYYGDYYGTYVSLRAICVANGPKSTIEGAVTFIENNRQPDGSWTERQESSPLQTAL
ALQALSIGKKHLGLTIDEQWLQSSLNYLQQTCDANGNWPSSPFIRMPMGRPMGFVHTILT
YESAAITSNYVAKACNHLYQNHINQN
>B2ICC0|squalene-hopene cyclase|EC 5.4.99.17|Beijerinckia indica subsp. indica (strain ATCC 9039 / DSM 1715 / NCIMB 8712)|TrEMBL
MPEEAILTETHPLDATTIETAITRARKALLGEQRADGHFVFELEADVSIPCEYILFYHFI
GRPAPAELEAKIGHYLRARQSAEHDGWPLFQDGAFNISSSVKAYFALKAIGDTPDMPHMQ
RARTAILAHGGAAAANVFTRSLLALFGLIPWHGIPVMPIEIMHLPEWFPFHIAKISYWGR
TVLVPMMVVHALKPKPANTCTIRIDELFVIPPDQVRHWPGSPGKRFPWTAIFAGIDKVLQ
IAEPYFPRRSRQSAIDKAVAFVTKRLNGEDGLGAIYPAMAYSALMYLSIGRSLSDPHIQL
VLKAIDKLVVVKDHEAYVQPCVSPVWDTALASHALMEAGDGDKPILDSLKKGLAWLKPLQ
VTDIAGDWAWKKPDVKPGGWAFQYGNAYYPDLDDTAVVVMAMDRARDRWPEIDEDNFRPS
IARAREWIVGLQSENGGFGAFDADNDRDYLNAIPFADHGALLDPPTADVTARCISMLTQL
GEKPENSETLRRAIAYLFAEQEKDGSWFGRWGLNYIYGTWSVLCSLNAAGIAHDAPEVRR
AVAWLRTIQNEDGGWGEDAESYALDYAGYQQAPSTSSQTAWAVLGLMAAGEKDDPAVARG
IAYLTRTQGEDGFWTEKRFTATGFPRVFYLRYHGYSKFFPLWAMARYRNLHNGNHASVLT
GM
>A0A553ZP21|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. MZ03-48|TrEMBL
MTATTDGSTGALPPWAPSASDAADHTEDPVGIAQQARRATERATAYLLSVQDPAGWWKGD
LETNVTMDAEDLMLRQFLGVRDTQTTEAAARHIRGEQREDGAWTTFHGGPGDLSTTVEAY
VALRLAGDAPHAPHMARAAARVREAGGIAASRVFTRIWLALFGWWKWDDLPELPPELIHL
PKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPADPNPPRPLAPATSW
DGLFQRLDRALHLYRKVAVRPVRAAAMRSAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVLKAGLASLDRFAVWREDGSRMIEACQSPVWDTCLATIALADAGLPADHPQL
VKAADWMLAEQIDRPGDWTVRRPHLPSGGWGFEFENDNYPDIDDTAEVVLALRRVDHPDP
RRIEEAVARGVRWSAGMQSKNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLADTGRADHPRARRGLAWLLADQEPCGAWFGRWGTNYLYGTGSVLPALAAAGIPGSHP
AVRRAVAWLERVQNADGGWGEDQRSYQDKETWAGRGASTASQTAWALMALLAAGERDGEA
VRRGVRWLAGTQLPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVGGGPAAAP
LGA
>C0ZG69|squalene-hopene cyclase|EC 5.4.99.17|Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599)|TrEMBL
MRIGTTTNPSMPFPLSSSGAVFYREVNELREVQQEINRIQAFLLQRQQEDGTWRFCLESS
PMTDSHMIILLRTLGIHDERLMEKLTAHITALQHDNGAWKLYPDEQEGHLSTTIDSYYAL
LLSGKYTKNEPRMALARSFILEKGGLTQANMLTKFATALTGQYQWPSHFLVPVEIALLPP
SFPVSFYDFVGYARVHLAPMMIVADRNYVKKPDNAPDLSDLYADTPISRGLYPHRFLENF
LKEGQSFLATIHDSLQQLPFLPGQLHKLALRRLEQYILARIEPDGTLYNYSTSTFFMIFA
LLARGFSPKDPLIQKAMQGLTGSVYDYENGAHLQLATSAVWDTALLTFSLQKSGLSPTHP
AIQKANRYLLRKQQHTYGDWKIRNPNGKPGGWGFSDYNTMNPDIDDTTAALRSLRLLART
DVTAATAWKRGLEWLLSMQNDDGGWPAFERNTDADFIRHLPIEGADTVSTDPSSADLTGR
TLEFLGNYAGRTLTDLHVEKGVRWLLKHQESDGSWYGRWGIAYLYGTWAAITGLMAVGFS
PTEPAIQKAVAWLVANQNPDGGWGESCQSDLKKTYVPLGASTPSQTAWAIDALIAVSSKP
TAELQRGIRYLLTHNQANDWTTRYPTGGGRPGGTYFAYHSYRWIWPLLALSHYQVKYANT
>A0A651F1X5|squalene-hopene cyclase|EC 5.4.99.17|Phycisphaeraceae bacterium|TrEMBL
MHSTATMTPETEQLDLQARSGASVTELPAQANAALDRAMHALYSKLKDDNHWCAELEGDS
ILNTEYLLMKVILGQHTAPEATEDDLRRFDKMVVYIRMLQREDGTWGQYPGSPPDISACV
KAYFVLKLWGDDPDAEHMVRARERILALGGAEKINTFSMFYLACLGQVSWDACPSIPPEI
VLLPRWFPFHLTKVAAWTRTMILPLAICSAKRPIRRLPSTLCIGELFVDQRNRERLNTAR
DERDPFSWTNIFLTVDKALKLAQKSGVMLLRASAISRAEKWITERVRPETTDGLGAIFPP
MVYIQIAFQAIGYRRDHPVIVEAERQLDRFIVEEADHIRIQPCFSPVWDTGTALYAVTES
GITAEQDERLARVCDWLCDREVPLIGDWIENLRKQDRNITMGTTHAEPGKTACAAWAFEY
RNDWYPDVDDTAMVAMALTRAAGSDTTPRAQRWRDAGKRAVNWIIAMQNDDGGWAAFDRT
THREWMEAVPFADHNAMQDPSCADITGRTIESLITNGLATDHPTVHRALDYLLAQQRPDG
SWWGRWGVNYIYGTWQAVGGLGACGLRANNHPACARALAWYRSIQNEDGGFGESANSYLD
PSLAGVGPSTASQTAWAAISMMKLVEPHEIRDDESIRRAIAYLCNTQLTAHAPAEPPAHI
VPEPAGGWREEWYTGTGFPKVFYLRYHLYRHYFPVMALARYARMA
>A0A6B3MPV5|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO4A1|TrEMBL
MQTQDRIVNSGVTEAIANSQSYLLAQQYPDGYWWAELESNVTITAEIILLHKIWGTDKER
PLHKAEAYLRSQQRKHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDSALVRARDFILR
RGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPQWFPFTIYEMSSWARGSTVPLLI
VFDQKPVFDIQPSITLDELYTEGADHAKFELPRNSDWTDLFVLLDDGFKLAEDLNLVPFR
KQGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPVVQRGLEAIDRFAIE
TPDSYRVQACVSPVWDTAWVLRAMVESGLEPDHPALVRGGEWLLQQQILDYGDWVVKNPQ
GKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLKQAAIARGLAWIASMQCNQGGW
AAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEMLGSCNLSIESQQLEKAIAFLIQ
EQEADGSWFGRWGVNYIYGTSSALSALSKIAPHTHQRSIERGAAWLVKCQNLNGGWGETC
LSYDDPSLKGLGISTASQTAWALIGLMAAGEATGNWARDAIEMGVNYLVSTQQPDGSWDE
TEFTGTGFPSHFYLKYHFYQQYFPLLALGRYQMSVSS
>A0A838L6E8|squalene-hopene cyclase|EC 5.4.99.17|Sphingomonas chungangi|TrEMBL
MLDVEDIATDPLDGIDAAIGRATTALKRDQKADGHWVFELEADATIPSEYILLRHYLGEP
DDLELEAAIGRYLRRIQGSHGGWALYHDGAFDISATVKAYYALKMIGDDIDAPHMARARA
EILKRGGAAASNVFTRIQLALFGAGKWSGVPEVPVELMLAPKWFPINLYRMSYWARTVIV
PLIVLTALRPVARNPRGVKIDELFVPGNPPLKRALPGKWQWEMGFGALDVVLKRGRRLWP
KTVRKKAIDACVAFVTERINGTDGLGAIYPAIANSVMMFDALGYGPDHPERALAREAIEK
LLVHRDDGEVYCQPCVSPVWDTALAAHAMLEAGEDEAATKGLDWLTPRQILDVRGDWAEQ
RPEVRPGGWAFQYGNDHYPDLDDTAVVVMAMDRARGKLGDRYDEAIDRGVEWNAELQSHD
GGFAAFDADNTHFYLNDIPFADHGALLDPPTADVTARVVSMLAQVGEPVDSPRMKAALEW
LRKDQHPEGSWWGRWGVNYIYGTWSVLCALNAAGVDPANAMVRRAVRWLVTIQNSDGGWG
ESCDSYDLARKGHEAASSIASQTAWALLGLMAAGEVDHPAVVRGVAWLERHQAEDGLWGQ
EHYTGGGFPRVFYLRYHGYPKYFPLWALARYRNLKRGNTRRVEFGM
>W6I4X1|squalene-hopene cyclase|EC 5.4.99.17|Granulibacter bethesdensis|TrEMBL
MPKDIPADLASEAISGDMLEQAVLRASMALHRKQQTDGHWVFELEADATIPAEYVLLEHF
LDRIDDDLERKIGVYLRRIQGDHGGWPLFHEGAFNLSASVKAYYALKAIGDDPDAPHMRR
AREAILAAGGAERSNVFTRIQLALFGQIPWRGVPVMPAELMIAPKWFPINMWKVSYWSRT
VIAPLLVLMDRKPKARNPRNVHVRELFLNDPDRIRDWIRGPFRSGWGHFFKYLDSVLRVV
EPVALKPMRPRSIRLAVDFVRERLNGEDGLGAIYPAMANSVMMYDVLGYSPDHPQAAIAW
ESVRKLLVIKEDEAYCQPCLSPIWDTGLSGHAMAEAEGAVSPGVAAACDWLRNRQITDVV
GDWAEIRPGVQPGGWAFQYNNAHYPDVDDTAVVAMLLHRQGDPAHNESIRKAREWIIGLQ
CRDGGWGAFDADNDKDYLNHIPFADHGALLDPPTADVTARCISFLAQLGNPGDKPVIDRA
MTWLRKEQEADGSWFGRWGTNYIYGTWSVLCAMNAAGVPHDDPAIRRAVNFLVATQREDG
GWGEDEETYDPASGAQPGRYKESTPSQTAWALIGLMAAGEAEHAATRRGIAYLQATQKPD
GEWDEAAYTAVGFPRVFYLKYHGYRQFFPLMALSRYKNLRSSNMKKVSFGF
>A0A7C1B0R6|squalene-hopene cyclase|EC 5.4.99.17|Thermodesulforhabdus norvegica|TrEMBL
FPEGRRSVRPKLDRPKNFFSWDSLFYWADWLMNRYVTFPFHPGRETAIKLCIEWIIRRQE
ADGAWGGIQPPWVYGLMALYNEGYDLDHPIMKRGLEALDAPHWSYWVGDSLHIQASNSPV
WDTVLTMVALLDCGEDVNSSRMLQKALDWLLEQQILDCYGDWSVKVRGVESGGWPFEMAN
KYYPDVDDTAVAMTVLARVLKKLDGDSRQISRALARAEKWTRRMQSSNGGWGAFDKDNMN
LLVTKIPFCDFGEVLDPPSVDVTAHVVEALAYLGYTRRDPNVAKALRYIRSEQEEDGSWF
GRWGVNYIYGTSAVLQALRAIGENMSQPYVRRAAEWLVQHQNEDGGWGETPASYMDKRLR
GVGESTPSQTAWALLGLMSVENEDYNDAIERGIRFLIKCQKDGTWDEPQYTATGFPGYGH
GGRITSGGFDETLDQGIELGRGFMINYNMYRHYFPLMALGRARRYFEKRGQSTSLLFG
>A0A552GHG1|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa Ma_QC_C_20070823_S13|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSDGYWWAELESNVTITSEAILLHKIWKTDK
KRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKAREFI
LAKGGISKTRIFTKMHLALIDCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKIGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKAVDNFAIE
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDEKIKKSVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVKMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRHQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLITQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A3R8Q809|squalene-hopene cyclase|EC 5.4.99.17|Saccharopolyspora rhizosphaerae|TrEMBL
MLSQGAARAHARLAAQAACDHLLSLQSPEGWWKGELETNVTMDVEDLLLRQFLGIRTESE
TEQSARWIRSQQREDGTWANFYGGPGDLSTTVEAYTALKLAGDDVDAAHMRTAREWILAH
GGLEDTRVFTRIWLALFGEWSWDELPAMPPEVVLLPKWFPLNVSDWACWARQTVVPLTVV
CTLRPRRDLGISVRELRTGRPAERPTFEWSWGYGFHRLDRVLHRYHRRPVRSLRRHAMLR
AAEWIVARQEADGSWGGIQPPWVYSLLALHLLGYPMDHPVIAKGLAGLERFLIRERTPEG
PVRRLEACQSPVWDTVLGVQALRDAGVPADHPSLRRATDYLLAEEIRVQGDWAVQRPELP
AGGGWAFEFDNDGYPDIDDTAEVLLALNKIDHPDREAVRGAIERGVRWLRGMRSKDGGWG
AFDADNTRQLVRTLPFCDFGEVIDPPSADVTAHVVEALAVLGERDQVLRDGVNWLLAHQE
RDGSWFGRWGANHVYGTGAVVPALVAAGVDPQHRALRDAVRWLEAHQNDDGGWGEDLRSY
DDPQWIGRGTSTASQTGWALMALLAVRRHDTDAVRRGIGYLARSQRADGGWDEPQFTGTG
FPGDFYINYHLYRVIFPLTALGRYLRDGE
>A0A6B1KU30|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5464|TrEMBL
MTATTDGSTGALPPRAAAASETDTDTPAAAGVPEAAARAAQRATDFLLSRQDAQGWWKGD
LETNVTMDAEDLMLRQFLGIRDEKTTQAAALFIRGEQREDGTWATFYGGPGELSATIEAY
VALRLAGDEPGAPHMAKASAWIREQGGIAAARVFTRIWLALFGWWKWEDLPELPPELIYF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPADPNPAKPLAPAFSW
DGAFQRMDKGLHALRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLQHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLAAIALADAGLPADHPQL
VKAADWMLGEEIVRPGDWSVQRPGLPPGGWAFEFHNDNYPDIDDTAEVILALRRIAHHDP
VRVDKAVGRGVRWTLGMQSKNGAWAAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIEWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALVAAGIPAAHP
AIRRAVTWLESVQNDDGGWGEDLRSYKYVNEWSGRGASTASQTAWALMALLAAGERDSKA
VERGIEWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGEPFADR
HQASGAAGKPLAGAEGAE
>A0A846FF95|squalene-hopene cyclase|EC 5.4.99.17|Cyanothece sp. SIO1E1|TrEMBL
MQTQDKTTVATEFKLTTAHRQVDAAIAASQNYLLSLQTAQGYWWADLESNVTITAEVVLL
HKIWGTDKTRPLHKAETYLRAQQRDHGGWELYYGDGGELSTSVEAYMALRLLGVPTTDPA
LVKARAFILERGGISKTRIFTKFHLALIGCYNWRGIPSIPPWLMFLSAPLPFTIYEMSSW
ARGSTVPLLIVFDQEPVFKVDPAITLDELYTEGAEYAKFELPRNHNWTDLFVHLDKAFKL
AERLDLVPFRQAGLKAAEKWVLERQEATGDWGGIIPAMLNSMLALRCLGYDVADPIVERG
LVAIDRFGVETEDIYWIQPCVSPVWDTALVMRSLVDSGLAPEHPALVRGGQWLLDRQILD
YGDWAVKNKQGKPGAWAFEFDNRFYPDVDDSAVVVMALNAIQFPNEALKQAAIARAVDWI
ASMQCRPGGWAAFDLNNNQDWLNALPYGDLKAMIDPNTADVTARVLEMVGRLEQNSGTKY
PVGSRSGVNKTQNSLTSYASLSIAQIERAVAYLINEQEPEGCWFGRWGVNYIYGTSGVLS
ALALIAPQTHKTQIERGAAWLVSCQNSDGGWGETCGSYGDPTLKGQGDSTASQTAWALQG
LLAAGEATGNFAKPAIQAGVNYLLVTQRSDGTWDEDYFTGTGFPSHFYLKYHLYQQHFPL
TALGRYVQLMG
>A0A5P1YJQ5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces tendae|TrEMBL
MTATTDGSTGAASPSRVAAASENDTDIPEAAGVPDRAASAMRRATDFLLSRQHDEGWWKG
DLETNVTMDAEDLLLRQFLGIRDEDTTRAAALFIRGEQREDGTWATFFGGPGDLSATVEA
YVALRLAGDAPDAPHMAKASAWVREQGGIAACRVFTRIWLALFGWWKWEDLPELPPELIW
FPTWVPLNIYDFGCWARQTIVPLTIVSAERPVRPAPFPLDELHTDPALPNPPRPFAPANT
WDGAFQRLDKGLHAVRRAIPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLNHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPR
LVKAADWMLGEQVVRPGDWSVRRPHLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHHD
PDRVDSAVGRGVRWNLGMQSRDGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGLAHDPRTRRGVAWLLADQEPDGSWFGRWGVNYVYGTGSVVPALTAAGIPTSH
PAIRRAVAWLEKVQNEDGGWGEDLRSYRCTKEWSGRGASTASQTAWALMALLAAGERDST
AVERGIAWLADTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFTK
KPAEATAASGQALAEAKGS
>A0A7V7FMJ2|squalene-hopene cyclase|EC 5.4.99.17|Rhodospirillaceae bacterium|TrEMBL
MEKVVEETLDWLVSRQANDGHWAFELEADATIPAEYILLNHFLDQVDGEIETKLATYLRS
IQADHGGWSLYHGGDFNISASVKAYFALKLAGDDIDAPHMIQARNAILDHGGAAKCNVFT
RCALALFGQMPWRAVPVIRVEALLLPKWAPFHIDKVSYWSRTVMVPLMILAALKPMARNP
KNVDIGELFIIPAEKVRNYLANPTGHWLGTVMIFVDRVARLAVPFFPKFLEDRALDRGMA
FIKERLNGEDGLGGIFPAMANTVMAFDAIGMARDHPDFVIARKAIAKLLIFKDGMGYCQP
CLSPVWDTSLAIHALMEAGLAGDDPVVEKANEWLRGRQILDVMGDWKANRGHIRPGGWAF
QYRNDHYPDVDDTAVVVMAMSRARGDADREAIQRATEWILGMQCRNGGWGAFDADNEYYF
LQHIPFADHGALLDPPTADVSARCIGMLAQLGYDMDHPAVARGYEFLRREQEDDGSWFGR
WGNNYVYGTWSVLCALKASGEDMRAAYIRKAVDWLKSRQRADGGWGEDCASYWQHRRDEV
KESTPSQTSWAILGLMAAGEVNSKFVRRGIDYLLKAQRNGGKWHEEYFNAVGFPRIFYLR
YHGYSSYFPLWALARYRNLTRGGGKLPKFGM
>A0A7K3R2M3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces bauhiniae|TrEMBL
MTATTDGSTGATIPPRAAAASDTDSTDPLAAGVPEAAERAAARAIEHLLARQDPEGWWKG
DLETNVTMDAEDLLLRQFLGIRDEAVTRAAALFIRGEQHEDGAWATFYGGPGELSATVEA
YVALRLAGDAPNAPHMARASAWVRERGGIASARVFTRIWLALFGWWKWDDLPELPPELIW
FPTWLPLNIYDFGCWARQTIVPLTIVSARRPVRPAPFPLDELHTDPARPNPPKPLAPLAS
WDGAFERLDRVVHRLRGAVPRRVRRAAMNAAARWIVERQENDGCWGGIQPPAVYSVIALH
LMGYDIKHPVMRAGLESLDRFAIWREDGSRMIEACQSPVWDTCLAVIALADAGVPADHPK
LLKAADWMLAEEIRRPGDWSVKRPELLPGGWAFEFHNDNYPDIDDTAEVALALRRVSHPQ
PDRVDGAIARAVRWNFGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMMAAEGLAHDPRTRRGIGWLLAEQEADGSWFGRWGVNYVYGTGSVVPALTAAGLPVSH
PAIRRAVHWLQQAQNDDGGWGEDLRSYSYAREWSGRGASTASQTAWALMALLAAGERDSE
AVERGVRWLADTQRDDGSWDEPYFTGTGFPWDFSINYHLYRLVFPLTALGRYLHGDPFDK
APLAARRGVRAMAGGS
>A0A8I2D2B5|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MRQTGGQTTDCVCAPGIDAGPALGARLDLAVERARDNLAGQQREDGHLCAQLEADITLES
DLIIALHFLGRARIHADLMAKAAREILAQQLPGGGFSTFPGGPPDVSATVKAYFALKLAG
YPADAEPLARARAAIAALGGITRCNTYTRFYLALFGQYDWKGVPEILPEIMLLLPWFPLS
LYSMSSWTRAIIVPLMIVNHYRPLAPTPEGGGIDELRGDRRAERTLYVESRNGTSPWKRV
FVSLDPLLKLWSRRPIAAVRGRALRKARSWILRRQHRSDGLGAIWPGIVNTAFALKCLGL
RDGDPVLERTIGQMLGLVIEDGGRLKVQPCKSPVWDTALTMIGWLRAGMPAGDPALARAA
KWLLDREVRLPGDWRVRRPRAAPGGWYFEYANEFYPDLDDTAVVVMALACVDLGPEQPVL
QSAVDRALAWVLAMQNRDGGWGAFDADNRHPILCDLPFADHNAILDPSTPDLTGRVLEMC
GRLGFTEKEPEIARAVRFLIGAQEPDGSWFGRWGVNHIYGTAAVLVALNAVRHDMTAPEV
VRAAGWIERVQNPDGGWGERCDSYHRPDARGRGESTPSQTAWAMLALMAAGRWDSPALAR
GAEYLLAGQESDGAWRERNFTGTGFPSVFYLKYHFYPRYFPLMALGAYRARSLNSWPIAI
SVKPSLAAYRRVPARPRLKFPLHQSLTIGKYILGRKLRRQARFPMVLMLEPLHRCNLACA
GCGRIKEYRDLMGSELSLAECLDSAAECGAPVVSVCGGEPLIYKDIAPLVAGLVAQGRYV
YLCTNGQRLAAAAPEFTPHKRLILNLHLDGPRALHDAITGRPGSFDRAVAGIAAARARGF
RVTTNTTFYATTKPADLRELFEHLLPYGVEGHTVSPAYAFAGAEGGDEFFLSREEIKARF
GGLRALARRFPLLCSPVYLDFLLGTRDLPCAPWANPTRNVAGWRAPCYLLLDRHYPTFKD
YSEGVDWENLGPGKDRRCRDCAVHAGFEPSAVLGGGAGLRDILRIARWQLG
>A0A3M1T2D0|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MGVVFVPIAGYGGAPRRGRGTRGAAPERVPSRRKRGKTLSQTDQSYASSLFARQQVSHEQ
RLAQSLARARSALLDLQHAEGWWNGEDEANQTLDAQYIFLLHYTGLLERPHYREKARKLG
NWIRRTQRPDGTWPIYYGGPGCISVTTEAYAALKLLGDPADAPHMVKAREFIRAQGGPAK
TRMLTRYQLALLGELDWSACPSLPLQLIIAPRLTRFNIYELSYWARVCTVPLAVLADVKK
VVPVPEGRGVAELFPAPVAPDVLYAGADPKAFSWGNLFLQADKVFKWMERTGIYPLRSSC
RERCKQWILDHQDESGDWGGIFPAIANSLLALYVLGMDVDDEVFVKGMQALERFEWPDEA
RDETHIAPCVSPVWDTAWSVLALAESGLPPDDPALARACDWLVSMQIKRKGDWAVKAPHV
PAGGWAFQFYNDFYPDTDDSAVVMMALTNGSPESKDARLAAIDLGKRWLLGLQNSDGGWG
AFELEVNQEVYNEILYNDEKNMLDPSTVDVTGRVLEMLGLLGASREDPVVQRAEAYVRRE
QEADGKWWGRWGVNYIYGTWSVVRGLAALGVGPDDPAMKAAADWVESYQQADGGWGESCA
SYLPGREAEPMDPCPSQTAWAVLTLVAAGRAQGTACRRGAEWLLAHQEDEGLWSEEAFTG
TGFPNAFYLRYHHYPKYFPVLALSAYRNALAR
>A0A6N7Z5C2|squalene-hopene cyclase|EC 5.4.99.17|Amycolatopsis pithecellobii|TrEMBL
MTVTALPAATAEATDAAGTLARAVAHLKGLQESAGWWKGELETNVTMDAEDLLLREFLGI
RTATETDEAARWIRSQQREDGTWATFYGGPGELSTTIEAWVALRLAGDAVAAPHMRAAQE
FVLANGGLENSRVFTRVWLALFGLWSWDELPNMPPELIFLPSWFPLNVYDWGCWARQTVV
PLTVVATLKPVRPLAFGVDELRTGKRPRKNLKPWTWSGAFEYLDKALHTYAKLPVKPMRG
WAMRQAAEWILARQEADGSWGGIQPPWVYSLLALHLLGYSFEHPAMKAGLKGLDGFIVRE
QTPDGWVRRLEACQSPVWDTALAMTALHDAHVPADDPALVQAADWLLGEEIRVTGDWAVK
RPATPPGGWAFEFANDIYPDTDDTAEIVLALRRTAFPDRPRLKGAVERAITWVQGMQSSD
GGWAAFDADNTRELTTKLPFCDFGAVIDPPSADVTAHVVEMLAAEGLAGTTECRRGVRWL
LDAQEDNGSWFGRWGANHLYGTGAAVPALVAAGVSPADPVIRRAVAWLEQVQNADGGWGE
DLRSYRDPAWVGKGDSTASQTAWALLALLAAGERESSTVERGVDWLARTQRADGTWDEPQ
FTGTGFPGDFYINYHLYRLVFPISALGRYLAPESPA
>A0A7C5Q1Z0|squalene-hopene cyclase|EC 5.4.99.17|Hyphomicrobiales bacterium|TrEMBL
KDDGHIVFELEADATIPAEYIFLNHFLGELEPELENEMGEYLRSIQSERHGGWPLFHDGD
FNISASVKAYYALKILGDDVDAPHMARARKAILDFGGAQKANVFTRYALALFGQVPWRAV
PAMPVELMLMPRWFPVNTWKFSYWSRTVIGPLLILAAHRPLAKNPRKVSCAELFTKPVDE
IRVWNTNPTGSKWGEFFLGLDKILQPLETHVLPHLPFRKKAIKRAIDFITPRLNGEDGLG
AIFPAMANATMAFQVLGYSKDHPDYKTALASVRKLVVETRDKRKGAPRYCQPCVSPVWDT
SLAAHALLDAGVERDDEKLVAMCDWLAGEQITGCVGDWAVNAPGLKPGGWAFQYKNDYYP
DVDDTAVVGMLLHRVDAKKYARQIQLAADWIEGMQSSNGGWGAFDIDNNAEFLNSIPFAD
HGALLDPPTVDVTARCLSFLAQTGYRRNHKCIERGVQFLKDEQEADGSWFGRWGTNYIYG
TWSALCALNAVGEDMKSPWVQKAVKWLKDRQRADGGWGEDGATYWQERRDEVKTSTPSQT
AWALLGLMAAGEVDAGEVDKGVKYLNA
>A0A4Q6I7K6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. F001|TrEMBL
MTTTDAGAFVPGVERSLALAVQALRERQDPTGYWKGDFETSLIGESGEVILRHYLRLPKD
ETVAAAARTILSEQTPTGGWASYHQGPDELLLSVFCYVALRLAGHDPDEPEMRAAAASVR
GNGGIESVDNLIMLAWLALIGLWPWRDIPLIPPEIVLLPTWCPGNIYQIGAAARGIVVAN
SLFMARRPVVPAGFGIRELFAEPGARRLPRSFAVRCATTLSHWYARRPIGPLRRRAIRKE
SRWLIRTQEKDGSWGGNWPQTANVVMGLDAIGFPQDHPVVTAAMAGLDRYVVEKDGQRRI
EMWTSVVMDTALALSANAMAGGPEEKAAAEPAVRWLLANQVTELGDWAVLTDNPVPGGWP
YEFTNNANPDADDTAFAVAALRRVHPRGTDPAVDAACERARRWLLSQQGEDGGWAAFEPL
RWRLPGRDKLARIGFLEAPSADITGHVLEALGADGQAHTPAARRGIEWLRRTQQPNGSWP
GWWACYHLHGTSAAVTGMAACGVPGSDPAMARACDWIVAHQQSDGGWGEDIRALHDPAWI
GRGDSTPSQTAWALLALIAGGRADSGPVRAGLDFLIRTQQADGDWAEPWHTWVVHHDGLY
WRDSLLRLIYPVMAMSAYRAAVDGTELR
>A0A5N5W8Y6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces mobaraensis|TrEMBL
MTATTDGAGALLPRVAEAGHSATAVTEVKEEAAGGAPAAVRAAAERATARATEYLLSRQN
EQGWWKGDLETNVTMDAEDLLLREFLGIRDDRTTRAAARWIRSQQRPDGTWATFHGGPGE
LSATVEAYVALRLAGDAPDEPHMAAASAWVRERGGIAASRVFTRIWLALFGWWKWEDLPE
MPPEIMFLPKWMPLNIYDFACWARQTIVPLTVVGAHRPVRPAPFALDELHTDPRRPNPPR
PPAPAATWDGFFQRLDKALHAYRRVAVRPLRRAALNAAARWIVERQENDGCWGGIQPPAV
YSVIALSLLGYDLDHPVLRAGLESLDRFAVWHEDADGEPVRMIEACQSPVWDTCLATIAL
ADAGLAPDHPALVKAADWMLDEQVLRPGDWSVRRPKLQPGAWAFEFHNDNYPDVDDTAEV
VLALLRVRHPDPARVQEAVRRAMRWTVGMRSRNGAWAAFDVDNTSPFPNRLPFCDFGEVI
DPPSADVTAHVVEALAVLGKQHDPRARGGIEWLLAEQEECGAWFGRWGVNYVYGTGAVVP
ALVAAGLPGSHPALRRAVAWLESVQNADGGWGEDLRSYRDADWMGRGASTASQTAWALLA
LLAAGERDSPAVERGVAWLADTQRPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALG
RYLHGEPFAAREV
>B4WIK8|squalene-hopene cyclase|EC 5.4.99.17|Synechococcus sp. (strain ATCC 29403 / PCC 7335)|TrEMBL
MSISALQTDRLSQTLTQSVVAAQQHLLSIQNPEGYWWANLESNASITAEVVLLHKIWGTL
DSQPLAKLENYLRAQQKTHGGWELYWNDGGELSTSVEAYMGLRLLGVPASDPALVKAKQF
ILHRGGVSKTRIFTKFHLALIGCYRWQGLPSLPAWVMQLESPFPFSIYELSSWARGSTVP
LLIVFDKKPVYPLQPSPTLDELFTESAENVRWELEEKGDWSDAFLWLDKAFKLAESVDLV
PFREESIRKAEKWVLERQEPSGDWGGIIPAMLNSMLALRALGYSVSDPVVRRGFQAIDNF
MVESETECWAQPCISPVWDTGLAVRSLTDSGLSPNHPALVKAGEWLLDKQILSYGDWSVK
NPQGQPGGWAFEFENSFYPDVDDTAVVAMALQDITLPNEPLKRRAIARAVRWIATMQCKT
GGWAAFDINNDQDWLNDIPYGDLRAMIDPSTADITGRVLEMHGRFAADLDLANSYAADLS
PYRLSRGLNYLIKEQELDGSWFGRWGVNYIYGTGQALSALALIAPERCRIQIERGIAWFV
SVQNADGGWGETCESYKDKSLKGKGISTASQTAWALLGLLDVSFCLDPAAKIAVDRGIQY
LVSTQSEGTWQEESFTGTGFPQHFYLRYRLYCHYFPLMALGRYQRVINSSAGI
>A0A846ZFC4|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura latina|TrEMBL
MTTTEAPGLTGAAAAAVEAARDHLLGLQSPEGWWKAELETNVTMDAEDLLLRQFLGIRTE
AETREAARWIRSRQRADGTWANFHGGPADLSTTIEAYIALRLAGDPVDADHMLAAAKFAR
DAGGIEGSRVFTRIWLALFGHWSWDDLPVMPPELMFLPSRVPLNVYDWACWARQTIVPLT
ILGSLRPSRSLPVDLAELRSGVVPADDAKGWGRAFNALDRVLHVYEKAPVRPLRRAAMRR
AADWIIARQEADGCWGGIQPPWVYSLMALNALGYGLDHPVIKRGLDGLERFTIRDEKGRR
LEACQSPVWDTVLAMNALGDAGAAPGDPALLRAARWVVDEEVRGPGDWSVRRPGTPPGGW
AFEFDNDVYPDTDDTAEAILALRKVSLPEAEAPIERAVRWLNGMASRDGGYAAFDADNTR
ELCTKLPFCDFGAVIDPPSADVTAHVVEALSKEGLAESAVVKRAVVWLLKAQEADGSWFG
RWGANHVYGTGSVVPALIAAGVRPEKPAIRRAVAWLEEHQNGDGGWGEDLRSYDDPAWIG
RGESTASQTAWALLALLAAGERSAAVDAGVRWLVRNQRPDGNWDEDQFTGTGFPGDFYIN
YHLYRLVFPISALGRYLAGAA
>A0A7X8MYZ4|squalene-hopene cyclase|EC 5.4.99.17|Bacillus sp. RO1|TrEMBL
MKPLDKINEKLKDMISNLLSKQTDKGTWNFCFEGSIMTDAYMIILIRILELTDEEVMVKR
LVERIKSQQESNGAWKVYPDEDEGNLSATIEGYFSLLYSGYVAKDAANMRKAERFIRENG
GLAKSDWLTKMMLAITGQIKWPSVIKIIPIEIMFLPSWSPISIYQLVGYARAHWLPILIC
SNLNYSYVHSRTPNLTHLQGEGSDAEDQRLLEDMQNLQLYFKNTLKKLAGSPEILKQKAF
NKAEDYILERIEENGTLYSYFSASFFMVFALLALGYDKRNPLIENAFQGMKAYLCRNADQ
VFIQNSPSTVWDTALISAALQQAGVPHQHASIKQASNYLSSKQQQKYGDWAIKNPEVTPG
GWGFSDTNTFVPDIDDTTAALRAITPLAGTDNHFKHAWSKGVEWILTMQNDDGGWSAFEK
NTDNYLLSFIPFEYEDRVLFDPSTADLTGRTLYFLGEYTTIPQESDVFRKAKEWLEHNQE
ENGSWYGRWGNCYIYGTWAAITGLKAIGVSSDDPLISRAVKWLFSIQNEDGGWGESCESD
SKKRYIPLHHSTPSQTAWALDALISASEIPTPKIKKGIYSLLSLLEANDWRSTYPTGAGI
PGGYYIHYHSYKYIWPLHALSHYKNKYYETE
>A0A7V3WP71|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MHRARLAGQSQALNLKAGQVEAVDRAMRRAQEYLLSLQHAEGYWIGELIVDATLVSDMVA
YHHWNGSVDPVWERKAVNHILSLQLPDGGWNIYYGGPAEINATVKAYLALKLAGIPVTDP
RMLRAREVARSLGGIPRLNTFSKLYLALLGLFPWDYVPTIPAEIILMGKWFHVNFNEMSN
WTRSMLVPLSIINHFKPTRPLHPPVSLSELYPEGFHERDLRLPRDPQWLTWRNFFIAFDQ
FLKVIEKARLRPFRALALKKAERWMLDRFEGSDGLAAIFPAMLNSLIALKALGYPDDHPE
VLRAERELKKLEHETEDSVRIEPCFSPVWDTAITVIALAESGLPPDHPALERAVNWLLDR
EIRFRGDWAIKNPAQVEPSGWAFEFNNKWNPDVDDTAMVLLALRKVPTQNPARRDAAFKR
GLRWMLTFQCKDGGWAAFDKDCTKSILEKVPFADHNAMLDPECADITARVLELVGYEGFR
LDHPQVQKALRYLQAHQEPDGSWYGRWGVNYIYGTWQVLRGLRALNLNMNQPWILKARDW
LESVQHEDGGWGERANTYDDPVFKGRGPSTASQTAWALMGLLAFDDPWRPSVVRGVQYLL
QTQNPDGSWTEDETTGTGFPKVFYLKYDMYRNTWPLLALATWRRLARGPDGQTAQPPLAD
SSGRARSDRYFRI
>A0A7C2IQC8|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MTDPAPAAPRAPRLAGRSPDGLAARLDTALERSVARMFELQHGDGYWWAELESNVTMVAE
HLMLERFLGLHDEARWRKIVRYLLDHQREDGSWAIYYGGPGDVSVTIEAYFALKLAGWDA
ESPEMVRARRWILDHGGIGAARVFTKLWLALFGQFDWRALPAMPPEIIWLPPSFPFNIYE
FASWARATIVAILVVWHYKPVVAIPPEQGVQELYLDPRDRSRIRYQRSERLVSWRNFFLG
IDSILRAVDRLPPHSWRERALAACERWIVAHQEADGSWGGIQPPWVYSIIALRCRGYELD
HPVLAKAIRGLLVDFALEDERWFTVQPCVSPVWDTALMITGLREAGVPADHPRLVRAAQW
LADREIRFPGDWTVKVKGVEPSGWAFEFANDWYPDTDDTAEVLIALRLVKLGRDLAPLNA
RATAWLRAMQSANGGWGAFDKDNTKRFVAEIPFCDFGEVIDPPSEDVTAHVVEWLALNGA
SRRDPAVRRALRYLYATQTADGAWFGRWGVNYLYGLGAVLPALTAIGEDRRSAVFRKAVR
WLEAHQNPDGGWGETCASYDDAALAGVGASTASQTAWALLALLAAGETESDAVRRGVEYL
LRSQQANGEWEEPYFTGTGFPRDFMLKYHYYRLYWPLWALGRYRRLLRGDPIHLPGCDPW
S
>A0A7C3MD28|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia subdivision 3 bacterium|TrEMBL
GPAEINATVKAYLALKLAGVPVTDRRMLKAREVVLRLGGIPRMNTFAKLYLALLGLFPWE
YVPTIPPEVLLIGKWFHVNFWEMSNWSRAMFVPLSIINHFKPTHRPKSGITLDELYPDGF
NARDLALRPDPDKLFTWRNFFLWLDRLHKLAEWFAAHNLHPFRKRALKKAEQWMLERFEG
SDGLGAIFPAMLYSVIALRALGYPDDHPEVVRAEHELKKLEHETEDSVRIEPCLSPVWDT
AITLVCLAESGMSPDHPAMVRGAEWLLEREIRFRGDWQYKNPAQVEPSGWAFEFNNKWNP
DVDDTCMVLLALRHVPTSNPARRDAAFKRGLDWMLTFQCKDGGWAAFDKDCTKNILTKVP
FADHNAMLDPECADITARVLELLGYLGYSTAHPQIKKAIQFLKENQESDGSWFGRWGVNY
IYGTWQVLRGMHALNYNMTEPWLLKARAWLESVQHEDGGWGERCNTYDDPVFKGRGPSTA
SQTAWAVMGLCAFDDPALPSLRRGIEYLIRTQNADGSWSEEETTGTGFPKVFYLKYDMYR
NTWPLLALATYKKLLMNSKMPADGSKFDLAPQPQQARTESRQHT
>A0A6L7RZ50|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MSVEVSARPNALASAIERARRHLLGLQDPEGWWKGELESNVTIEAEDLFLRRYLGILDAG
TTERTARWIRSRRQPDGTWANFHGGPPDLHTTTEAYVALRLAGDEPDDEVMRQTAAWIRE
QGGVEATRTFTRFWFALNGWWSWDDVPAMPPEVMLLPPWWPLNIYDFACWARQTYVALTI
VRSHEPVCPAPFPIDELRTHRTPSMDQSLLTWTGIFNQVDRLLRWYQKCPIGWLRKAALS
RAEAWIVRRQERDGSWGGIQPAWVNSIIALTLRGYPLDHPMIARALDGLDTFTIDDGHTR
RVEACQSPVWDTAMAIEALTDSGTPGEDARLIQAADWLLDQEVRVKGDWSVRRPHLAPAG
WAFEFANDNYPDVDDTAEVGLALRRVDHPDPDRVDAALVRARGWLEGMQSRNGGWGAFDA
DNTNTLCRQPSFRDFGEVIDPPSADVTARALQFLAQEDALDTETTRRGLAWLRAEQETDG
SWFGRWGANHIYGLSVVVPALVAAGTPTGDPALRRAVAWLEAHQNADGGWGEDLRSYSDP
AWIGRGASTASQTAWALLALLEADDESPAIQPGIEYLIHTQREDGNWDEDFYTGTGFPGA
FYINYHLYRLLFPLMALGRYARKVGRDEDGM
>A0A6L7NIU6|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MTSRRATAGVNDLQLAAALDGATRWLLDDQHADGYWVGELEANVSITAEYLLLTHHLGIA
DREVWAKIVRYLRRHQHPEGYWSQWYGGPGELSTTIEAYFALKLAGEEPDAPHMVRARDW
VLAHGGIARARVFTKLWLALFDQYDWDRLPAMPPWLVLLPRWFPFNIYEFASWARATIVA
ITVVFSLRPTATVPAGAGVQELWCDPRQRRDFAVPRPRNPLSWSGFFWHLDSVLRLLERN
HVRPLHHRALGTAERWLLDRQEADGSWGGIQPPWVYAILALRALGYPLDHPVIRQGLAGF
RSFTREEPPPDEPDPQGARMLWTEPCLSPVWDTCLAAIALRDAGLPADHPALVRAGEWML
QEQVFSGGDWQVKNPDTPPGGWAFEFENDVYPDMDDSAYVLVALDDIALPDEAAKRRAID
AGLRWTLSMQSEDGGWGAFDVDNKAEFLTQIPFADFGATIDPPTADVTAHVLELLGRLGY
RGEFPPAKRALRFLADLQEPDGSWWGRWGVNYLYGLGAVLPALEALGESMSQPAVLKAVD
WLHRHQLPDGGWGEGCETYAEPRRAGAGPSTPSQTAWALMALIAAGEAESETVARGVRYL
MDRQRQDGTWDEPEFTGTGFSTDFMINYHLYRHYFPLMALGRYQKALAPA
>A0A0M0EMK8|squalene-hopene cyclase|EC 5.4.99.17|Komagataeibacter europaeus|TrEMBL
MTFHTGMENMTRESRPLTKTATSSDNTVSGTTFPAAGIQSVNGGGKGMAAAAGLRAMDNS
LSHAISSACDWLIGQQKPDGHWVGPVASNASMEAEWCLALWFLGLEDHPLRPRLGKALLE
MQREDGSWGTYYGAGNGDINATVESYAALRSLGYPADDPAISRAATWIASKGGLKNIRVF
TRYWLALIGEWPWEKTPNLPPEVIWFPNNFVFSIYNFAQWARATLVPLAILSARRPARPL
RPQDRLDALFPGGRANFDYELPARGERDLWGRFFRTTDRGLHWLQSRFLKRNTLREAAIR
HMLEWIIRHQDADGGWGGIQPPWVYGLMALHGEDYQFHHPVMAKALSALNDPGWRHDRGD
ASWIQATNSPVWDTMLAIMALHDADGETRFTPEMEKALGWLLDRQVRVKGDWSIKLPDVE
PGGWAFEYANDRYPDTDDTAVALIALSSCRNREEWKKRGVEEAISRGVNWLIGMQSECGG
WGAFDKDNNRSILSKIPFCDFGEALDPPSVDVTAHVLEAFGILGLPRHMPTIQRALAYIR
AEQEPDGPWFGRWGVNYLYGTGAVLPALAAIGEDMTQPYITKACDWLVAHQQENGGWGES
CASYMELSMVGRGVTTPSQTAWALMGLIAANRPQDYGAIARGCRYLIDLQQPDGSWDEKE
FTGTGFPGYGVGQTIKLDDPALSKRLQQGAELSRAFMLRYDLYRQFFPIMALSRASRLMK
LEK
>A0A7Z2GLQ0|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia acidisoli|TrEMBL
MNDLSHALPTEDELVSRPASADTVTPNPVSTPLPAFAAEFADTARPQPVAAQGAAALDAS
VVRATEAILADQRADGHWVYELEADATIPAEYVLLVHYLGETANLELEQKIARYLRRIQL
PGGGWPLFTDGAMDVSASVKAYFALKMIGDAEDAEHMVRARAAILAAGGAEQVNVFTRIL
LALFGVVTWYAVPMMPVEITLLPQWFPFHLSKVSYWARTVIVPLLVLGAKRPVAKNPRGV
RIDELFHCAPVTVGLNARAPHQSKGWFGVFRTIDGVLRVTDPLFPSYLRQRAIDAAVAFV
DERLNGEDGLGAIFPAMANAVMMYDVLGYPADHPHRAIARQSLEKLVTEHTEEAYVQPCL
SPVWDTSLAAHALLETGEARAEEAARRGLEWLRPLQILDVRGDWISRRPDVRPGGWAFQY
ANPHYPDVDDTAVVVAAMDRMDKLDRAHAYDTPIARAREWVVGMQSSNGGWGAFEPENTH
EYLNNIPFSDHGALLDPPTADVSGRCLSMLAQLGETPAASEPARRAYNYLLDEQEADGSW
YGRWGMNYIYGTWTALSALNAAGLEHGDPRMQRAANWLIQIQNDDGGWGEDGTSYKLEYR
GYERAASTASQTAWALLGLMAAGKVEHPAVARGIDWLQKTQREHGLWDETRFTATGFPRV
FYLRYHGYRKFFPLWALARYRNLTRAGETRVTVGL
>A0A5J6SNP3|squalene-hopene cyclase|EC 5.4.99.17|Psychrobacillus glaciei|TrEMBL
MNDTLSEEINRIISILKKDQSEVGTWDYPFETGITTDAYMIILLRSLTIDDEELIKELVV
RILSEQQDSGAWKLFYDEEDEGNVGTTIEAYYALLYSGYCSHDDVRMQEARQFILSNGGI
DKSNLLTKIMLAVTGQFSWEKIFTIPTEFVLLPHSFPMNFFDLSVFGRANIAPLMILAEK
KYIIKTNKSPNISDLYILNHNRWDEDYLLSALSNEWSPFLLSIKNRIEDLFGLPKQIHEL
AVEKTKQYMLDRIEPDGTLYSYFSSTFLLIFAFLSLGYKKDHPTIIHAVNGLKSMKCKID
GKTHMQFTTATVWNTALISYAMQEAGVSELDPVIKKTNKFLLTRQHDKYGDWVIHNPDSL
PGGWGFSNVNTLNPDIDDTTATLRSISKTVNKKTKFHSSWARGIHWVFSMQNDDGGWPSF
EKGVNKSILSMIPIEDAEYLLADPSSADLTGRALEFFGNFTNLKNDHDSIKLGVNWLIDH
QEPNGSWYGRWGICYIYGAWAAITGLVAAGISSDHPSILKSVKWLREIQNSDGGWGESCK
SDKMKTYVPLGSSTLTHTAWALDALIAAEEELTPEIISGIKYILENNDKDDWTTSYPTGQ
GMAGSFYIHYHSYRYIFPLLALAHYQKKFPNERLLTH
>A0A4S2VTK4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. LRa12|TrEMBL
MTATTDGSTGASLRPLAASASDTDITIPAAAAGVPEAAARATRRATDFLLAKQDAEGWWK
GDLETNVTMDAEDLLLRQFLGIQDEETTLAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDSPEAPHMARAAEWIRSRGGIASARVFTRIWLALFGWWKWDDLPELPPELI
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPARPNPPRPLAPVA
SWDGAFQRIDKALHAYRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPEDHP
QLVKASDWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHH
DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAVEGLAHDPRTRRGIQWLLDAQEADGSWFGRWGVNYVYGTGSVIPALTAAGLPTS
HPAIRRAVRWLESVQNEDGGWGEDLRSYRYVREWSGRGASTASQTGWALMALLAAGERDS
KAVERGVAWLAATQREDGSWDEPYFTGTGFPWDFSINYNLYRQVFPLTALGRYVHGEPFA
KKPRAADAPAEAAPAEVKGS
>A0A7K2TFV2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8352|TrEMBL
MTATTDGSTGAALPSHAASASDTTHITTHITTHVTTSDAADAASGAAARATQRATDFLLA
RQDPEGWWKGDLETNVTMDAEDLLLRQFLGISDEATTRAAALFIRGEQREDGTWATFYGG
PAELSATIEAYVALRLAGDDPGAPHMARASAWVRAQGGIAAARVFTRIWLALFGWWRWED
LPELPPEIVYLPTWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPAHPS
PSRPLAPAASWDGAFQRIDKALHAYRRLAPKRLRRAAMNTAARWIIERQENDGCWGGIQP
PAVYSVIALHLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLAAIALA
DAGVPADHPQLVKAADWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVV
LALRRVRHHDPERVEKAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVID
PPSADVTAHVVEMLAAEGLAHDPRTRRGVQWLLDEQEADGSWFGRWGVNFVYGTGSAVPA
LVAAGLPGGHPAIRRAVSWLESVQNEDGGWGEDLRSYRHVREWSGQGASTASQTGWALMA
LLAAGERESAAVERGIAWLVATQREDGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALG
RYVYGEPAVTRPPADREPAAGVKGR
>A0A6I6N5U3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces broussonetiae|TrEMBL
MTATTDGSTGATLPSHAAAASDTTLSTPEAAGVHQAATRAARRATDFLLARQDAQGWWKG
DLETNVTMDAEDLLLRQFLGIRDEKTTQAAAMFIRSEQREDGTWASFYKGPGELSTTIEA
YVALRLAGDAPDEAHMAKASAWIRERGGIAASRVFTRIWLALFGWWKWEDLPELPPELIY
FPTWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPASPNPPRPLAPVTS
WEGAFQRLDKGLHQLRKVVPRRLRRAAMDSAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVMREGIASLDRFAVWREDGSRMIEACQSPVWDTCLAAIALVDAGLPADHPQ
LVKAADWMLGEEIVRPGDWAVKRPGLPPGGWAFEFHNDNYPDIDDTAEVALALRRVGHHD
PERMDKAIARAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAAEGLAHDPRTRRGIDWLLAEQESNGSWFGRWGVNYIYGTGSVVPALTAAGLPGSH
PAIRRAVAWLESIQNDDGGWGEDLRSYKYVKEWSGRGASTASQTAWALMALLAAGEQDSK
AVERGVQWLADTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFER
GLLARKPHSEVKVG
>A0A7X5UQH7|squalene-hopene cyclase|EC 5.4.99.17|Saccharomonospora amisosensis|TrEMBL
MSEVHTEAALDGGVLETVERARSYLLSLQHEEGWWKGELETNVTMDAEDLLLRRFIGVDD
ERITAESARWIRSCQRDDGTWANFYGGPADLSTTVEAYTALRLAGDPADAAHLRSAREYI
LDSGGLEATRVFTRIWLALFGEWSWNDLPVLPPELMLLPDWFPLNIYDWACWARQTVVPL
TIVGSARPSRELGVSVSELRTGRRTRQPDSWLSWAGAFHGLDAVLHRLEKFPVKPLRGIA
LARAERWILDRQEADGGWGGIQPPWVYSILALHLRGYPVEHPAIRKALDGLEGFTIREHT
DEGWVRRLEACQSPVWDTALALTALLDSGLPADDPALLRAADWVIREEIRTDGDWRVRRP
RLEPSGWAFEFANDNYPDTDDTAEVVLAMNRVDHPEPRRLATVLERATVWVTGMQSADGG
WGAFDADNTQTLCEKLPFCDFGAVIDPPSADVTAHVVEMLAARGLADSEQARRGVRWLLD
NQEADGSWFGRWGANYVYGTGAVVPALVACGLPPTHKAVRAAIGWLVAHQNADGGWGEDL
RSYVDKSWIGKGTSTASQTAWALLAMLAAGERGQAVRRGVDWLARTQRADGGWDEPQFTG
VGFPGDFYINYHLYRLVFPLTALGRYVEVTRHEHTG
>A0A4R4YDX5|squalene-hopene cyclase|EC 5.4.99.17|Saccharopolyspora elongata|TrEMBL
MQQAARAVPVADARTALAAARDHLLSLQHPDGWWKGELETNVTMDVEDLLLRQFLGIRTA
GETEQAARWIRSQQRADGTWANFHGGPGDLSTTVEAYTALKLAGDDVAAGHMVAARSWIL
SRGGLEATRVFTRIWLALFGEWSWDELPEMPPELVLLPKWFPLNVADWGCWARQTVVPLT
VVCTLRPRRDLGITVRELRTGRPAERVRPQWSWKYAFHSLDRILHRYHRRPVKALREHAM
RRAAEWIVARQEADGSWGGIQPPWVYSLLALHLLGYPLDHPVLRHGLAGLDRFLVREQTP
AGPVRRLEACQSPVWDTVLGMQALRDAGVPGDHPSMLRAVDFLLAEEIQVKGDWSVRRPN
LPPGGGWAFEFDNDGYPDIDDTAEVLLALNRVDHPDRAAVRGAMERGVRWLRGMQSADGG
WGAFDADNTRQLVRKLPFCDFGEVIDPPSADVTAHVVEALAVLGHDDEVLRRGVRWLLDN
QEADGSWFGRWGANHVYGTGAVVPALVRAGLAPGDHALRRAVRWLEDHQNADGGWGEDLR
SYDDPEWIGRGDSTASQTGWALLALLAVGQHDTEAVRRGVQYLARTQRADGGWDEPQFTG
TGFPGDFYINYHLYRVIFPLTALGRYHAAGG
>A0A420F043|squalene-hopene cyclase|EC 5.4.99.17|Micromonospora globbae|TrEMBL
MTELLSPKTTTTVEAERPGADVLDEARDALRRARDHLLDLQDEAGWWKGDLATNVTMDAE
DLMLRQFLGIRTAEQTAETARWIRSQQRPDGSWAIFHGGPGDLSTTIEAYVALRLAGDTV
EAPHMAAAAAFVRAHGGVAASRVFTRFWLALFGHWPWSQLPAVPPELVLLPSWVPFNVYD
FACWARQTIVPLSIVRALRPVRSLGFGVDELRTNARPPRPPRLGSRPGLLYRLDRLASGY
ERIARGPVRRHALRRAAEWIVARQEADGSWGGIQPPWVYSLMALHLLGYPLDHPVLRAGL
DGLERFTVRTQTPDGPARWLEACQSPVWDTALAVTALTDAGLPAEHPAVERAGRWLLSEE
IRVRGDWAVRRPDTPAGGWAFEFDNDGYADTDDTAEVIMALRRTGVPAEAAVLRGTRWLL
GMQSRDGGWAAFDADNTRAILGELPFCDFGEVIDPPSADVTAHVVEALAAENYAGTTPVR
RGVHWLLRAQEPDGSWFGRWGANHVYGTGAVVPALVAAGVPRRHPAIRRAVDWLFAHQNA
DGGWGEDLRSYRDPSWIGRGESTASQTAWALLALHAAGHGTGERALRAVRWLVDTQRPDG
GWDEPQFTGTGFPGDFYINYGLYRLVFPISALGRILGTRADEATVTR
>A0A7Y9WT14|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia bryophila|TrEMBL
MNDLSQAQPLDAVLPEFADATAVPATPDAPVTATTAAQAPDTSLDAAITRATDAILAAQK
PDGHWVYELEADATIPAEYVLLVHYLGETPNLELEQKIGRYLRRIQMAEGGWPLFTDGAL
DISASVKAYFALKMIGDPVDAEHMVRAREAILAHGGAETVNVFTRILLALFGVVSWRAVP
MMPVEITLLPEWFPFHLSKVSYWARTVIVPLLVLNAKRPVARNPRRVRIDELFRGAPVNL
GPRDRAPHQHLGWFRFFSGVDVLLRAVDGLFPKATRDRAVRAAVAFVDERLNGEDGLGAI
FPAMANSVMMYDVLGYPADHPNRAIARQSIEKLLVIKDDEAYCQPCLSPVWDTSLVAHAL
LETGEAHAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYNNAHYPDVDDTAV
VVMAMQRSAALTQSDVDREAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGA
LLDPPTADVSGRCLSMLAQLGELPKDSEPAQRAFAYMLKEQESDGSWYGRWGLNYIYGTW
TALCSLNAAGFPHDDQRMKRAAQWLLSIQNEDGGWGEGGESYKLDYRGYERAPSTASQTA
WALMGLMAVGEVNHEAVARGVAYLQREQREHGLWDETRFSATGFPRVFYLRYHGYRKFFP
LWALARFRHLKRNGLTRVAVGM
>A0A7C0XD46|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MNLTPHSTIIQSLQYGIEKGIAWLLDNQRPEGFWLGNLETNSCMEAEWVLAMHFLGVEDD
PKFESVIRAILNEQRPDGSWEVYYQAPMGDINVTVECYTALRASGMPVDSPPLRKAREWI
LEHGGLVGLRVFTRYWLALFGEWPWDVTPALPPEIIFLPSWAPFNVYRFASWARGTIIPL
TVLRARRTVRKLSPEYRIDELFPESRSRFDYRSVRKKNTSLRQRPFYLFDRLLSRYNRFP
FCPGRELAIRKCLEWIIRHQEADGAWSGIQPPWIYSLLALHAEGYALDHPVLAAGLDAWN
KYWKFEKDGATYLQASNTPVWDTLLSLLAVLDCDQDFTATPQMQSALDWILNEQVMAGGD
WQVYVKDVEPGGWAFELQNDFYPDVDDTAVALIVLLRLLPVLPSGLRSRVDLAVNRAVAW
MNAMQSSNGGWGAFDKDNNSHCITLIPFCDFGETLDPPSVDVTAHVLEALGLLGRGLDDP
VVARAYRYIRAEQENDGSWFGRWGVNHIYGTAAVLPALKAIGEDMNALYVQKAAQWIVDH
QNPDGGWGESCGSYMDITLRGCGPSTASQTGWALMALVATGSHAYDHVIERGLEWLLATQ
RTDGTWNEPQYTGTGFPGYGTGERTDIAKAADNLNQGSELSRGFMLNYNMYRHYFPLMAM
GRTLHHLSE
>A0A841DH57|squalene-hopene cyclase|EC 5.4.99.17|Kribbella solani|TrEMBL
MTAERVASEAPADVRVQECLDAAVAYLRSLQHEDGWWKGDLATNVTMDAEDLMLRHFLGV
STAQTDAETARWIRSQQRDDGTWATFPGGPGDLSTTVESWVALRMAGDDPKAAHLASAAE
FIRSAGGVEKARVFTHIWLALFGLWEWDDCPDLPPELIFLPSWAPLNVYNWACWARQTIV
PLTIVSAHRPVHPVGFTVAELRSGAVAAPYAPVWKLDGAFQRLDVLLNAYTRWGPRGPLK
WLRRLAMRRATEWIVARQEADGGWGGIQPPWVYSLIALRLMEYPIDHPVLAAGLRGLEGF
TVHAETADGPVRWLEACQSPVWDTGLAVGALLDAGVPGDDETVLKATDWLLTEQIDAPGD
WQVRRPDLVSGGWAFEFANDGYPDTDDTAEIVLALRRVVHPEPDRLRGALDDAVAWTTGM
QSADGGWGAFDADNTDTTPLKLPFCDFGAVIDPPSADVTAHVVEMLAAEGKSSSAECRRG
VEWLLDSQEADGSWFGRWGTNHVYGTGAVVPALVAVGMPADDPVIQRAVRWVEAHQNDDG
GWGEDLRSYVDPAWVGRGDSTPSQTAWALLTLLAAEADGVAVQRGLAYLVETQRPDGGWD
EHRYTGTGFPGDFYIGYHLYRIVFPIWALGRYLR
>A0A4U6BT74|squalene-hopene cyclase|EC 5.4.99.17|Afipia massiliensis|TrEMBL
MTLLEDHKAAAAPTAPALESSIAAASSAILDTRKPDGHWVFELEADATIPAEYVLLRHYL
AEPVDAVLEAKIGNYLRRIQNENGGWSLFYGHEFDMSASVKAYFALKMIGDSVDAPHMKK
AREEMLRRGGAIKSNVFTRIMLALFGVVTWRAAPMMPVEIMLLPRWFPIHLTKISYWART
VIVPLLVLMNKKPRARNPLGVGIDELFLEDPKSIGMTAKAPHQSHLWFTGFSILDAVLRV
VDPFFPKKSRQRAIDKAVAFVTERLNGVDGLGAIFPAMANTVMMHDLLGYPKDHPHYVLA
RQSIENLLVIKDDEAYCQPCVSPIWDTALAAHAMIEVGGEKAEALAKAALDWLKPKQVLD
VEGDWIEKRPGVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRARGTLQAGTKYDEAIARGR
EWLLGLQSKDGGWAAFDADNLEYYLNNIPFSDHGALLDPPTEDVTARCVSMLAQLGETAK
TSEALARGIEYLRRTQLPDGSWFGRWGVNYIYGTWSVLCALNAAGVDHSDSVMAKGADWL
ISIQNSDGGWGEDGNSYRLDYKGYVKSETSASQTAWATLALMAAGKVDHPATQRGIAYLI
QNQTKDGLWTEPQYTGGGFPRVFYLRYHGYSKFFPLWALARYRNLRNTNSRFVGIGM
>A0A534PZW6|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MRREQDAWGSAGRGAEVGELARAALDRAVAHLLSRQNTEGWWKGELETNVTMDAEDLLMR
EFLGIRTREETALAANWIRNKQREDGSWATYYGGPADLSTTVEAYAALRLAGDPPEAEHM
KRAREVALGLGGTAHTRVFTRIWLALFGEWSWDDLPALPPEVILLPAWFPLNVYDFACWA
RQTIVPLTIVGSHRPVRPLPFSLSELRVGERREVIHPLSTWKGRLQRLDRALRWYERHPI
KRLRELSRRLACEWILQRQEADGSWGGIQPPWVYSVLALHLEGYPLDHPALARALHGFRR
FTIEQGDERRLEACQSPVWDTALAMIALRDAGVAPDHPALVQAAEWTLREEVRVPGDWCV
RRPHLEPSGWAFEFDNDRYPDVDDTAEVILALRAARTGDDAAREAALARAIAWTVGMQSS
DGGFAAFDADNTRALCRELPFCDFGEVIDPPSADVTAHVVEMLALEGRAEEPRVQSAVAW
LLREQEPGGSWFGRWGANHVYGTGAVVPALIAAGLPRDHIAIRRAVRWLSSVQNADGGFG
EDLRSYTSEGAPGLGDSTASQTAWALLALLAAGERGRSVERAVEWLARTQRADGSWDEPQ
YTGTGFPRDFYINYHLYRLVFPIQALGRYVSAIGAGR
>A0A494TCF5|squalene-hopene cyclase|EC 5.4.99.17|Sphingomonas paeninsulae|TrEMBL
MATLIEPTDILGAADACAKRAADALAALQRDDGHWVFELEADATIPAEYVLLKHYLGEPR
DAVLEGKIARYLRRIQADHGGWPLFAGGAFDISATVKAYYALKMIGDDVDAAHMTRARTA
IRAAGGAEAVNVFTRIQLALFGAGPWRAVPTLPVELILLPRWFPIHLSKMSYWARTVIVP
LLVLAAKKPVARNVTGVLVDELYVGRRVRPESKAQGTKRGWTLFFDGLDVVLKGVEPLWP
KRLRARAVAACVTFVTERLNGEDGLGAIYPAMANSVMMFDCLGLAENHPDRAIARASLDK
LLVVGEDEAYCQPCVSPVWDTALAAHAMMEAGGDDAEARADAALAWLKPLQVLDVKGDWA
DERPDVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRAKGRTGPVYDEAVARGVEWTVGLQS
RDGGWGAFDADNSYHYLNNIPFADHGALLDPPTSDVSARCVSMLAQLGERDTPRMKAALE
FLEKEQANDGSWFGRWGVNYIYGTWSALCALNAAGIDHQSPMMRGGVDWLMRTQNADGGW
GEDCDSYDLAYKGYTPAPSTASQTGWALLGLMAAGEVDNPAVERGVRYLMATQDDAGLWS
QEAYTGGGFPRVFYLRYHGYPAYFPLWAVARYRNLKRSNSAQVAVGM
>A0A7Y9NNM0|squalene-hopene cyclase|EC 5.4.99.17|Edaphobacter lichenicola|TrEMBL
MGISASNTKGADQLAQPRFGRMDVGLERIAEGVTRAKKWLFEQQHPDGYWCGELEADSML
ESDYIFMHTLLGTGEPGRMERAINEILRHQNDDGGWGLFPGGPSNISYGVKAYLALKLMG
WSKDHPVLVKAREWVLAHGGVVECNTFTKIYLCALGQYDYDAVPAIPPEIVLFPNWCYFN
IYEISSWSRGILVPLSIIYAKKPFKKLAPEQGIEELFVGGRENANLHLRWDKKKPFGWRN
VFLALDRIAHLAERVHIRPLRKIALKRAEEWMLERFEKSDGLGAIYPAMLNSIVALRCLG
RSVDDPQLIRALDEFEKLGIDCPDGTDDYSTPTFRMQPCFPPVWDTAQAMYALGEAGVRR
DDPRMLKAADWILSKEVRQKGDWAEKVKNVEPGGWYFEFNNEFYPDVDDTGQVLLALNCV
ENPRERYQYDACQRALNWIWAMQCKNGGWASFDRDNTKMIFQYIPFADHNAMLDPPTVDI
TGRMLEMLALYGVTRSDPRVEKAIQFILKEQEPDGSWFGRWGVNYLYGTFLVLRGLEAMG
FWNHEPAVQQAAEWIRMVQNADGGWGETCGTYDDPNQRGIGPSTPSQTAWAVLGLLAAGD
TRSDSVAKGIRWLVDRQHEDGSWDELVPGRNGESYYTGTGFPRVFYLGYHLYKQYFPLLA
LTTYERAMKSGTAH
>A0A550I9J1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. IB201691-2A2|TrEMBL
MTATTDGSTGALPPRAAAASETTEVTTPEAAGTVDTRDAARHAILRATDFLLSTQDAQGW
WKGDLETNVTMDAEDLLLRQFLGIRDEATTRAAGLFIRGEQREDGTWASFYGGPGELSTT
IEAYVALRLAGDAPDEPHMARASAWIRERGGIASARVFTRIWLALFGWWKWDDLPELPPE
LIYFPKWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDAGNPNPVKPLAP
VGSWDGVFQRLDKALHTYRKVAPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSII
ALHLLGYDLEHPVMREGLASLDRFTVWREDGARMIEACQSPVWDTCLATIALADAGVPAD
HPQLVKAADWMLGEEIVRPGDWAVKRPHLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVK
HHDPERVDRAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVT
AHVVEMLAVEGLSHDPRTRRGIEWLLAEQEANGSWFGRWGVNYVYGTGSVVPALVAAGLP
GSHPAIRRAVAWLETVQNDDGGWGEDLRSYHDVAEWSGRGASTASQTAWALLALLAAGER
DSKAAERGVAWLAETQLADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEP
FADRQGSFGRAS
>T2AYM1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIFMEKAANWLVKRQILDVIGDWGANVHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDCYSEAIARGAEWIIGMQSGNGGWGAFDVNNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAVGYLKCGQEVNGSWYGSWG
>T2AYD3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIFMEKAANWLVKRQILDVIGDWGANVHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDCYSEAIARGAEWIIGMQSGNGGWGAFDVNNEHHFLQ
HIPIADHGALLDPPTADVSARCLSMMAQLGYGLDNQAVARAIGYLKRGQEVNGSWY
>A0A6G2IC31|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. HUCO-GS316|TrEMBL
MTATTDGSTGALPPRAAAASETDTDTPVAAGVHEAAARAAQRATDFLLSRQDDEGWWKGD
LETNVTMDAEDLLLRQFLGILDEATSHAAGLFIRGEQREDGTWATFYGGPGELSATIEAY
VALRLAGDAPDAPHMARASAWIREQGGIAAARVFTRIWLALFGWWKWEDLPELPPELIYF
PTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPDRPDPPKPLAPAASW
DGAFQRLDKALHALRKIAPRSLRRAAMNNAARWIIERQENDGCWGGIQPPAVYSIIALHL
VGYDLQHPVMRSGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALVDAGVPADHPQI
VKAADWMLGEEIVRPGDWAVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHDP
ERVERAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLSKDPRTRRGIQWLLSEQEPDGSWFGRWGVNYIYGTGSVVPALTAAGLPAAHP
AIVRAVAWLESVQNDDGGWGEDLRSYKYVKEWSGRGASTASQTAWALMALLAAGEKDSKA
VERGVEWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGEPFAEK
PLAGAEGG
>T2AY11|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSMSDKTIMEKAANWLVERQILDVIGDWGVNAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDCYSEAIARGAEWIIGMQSGNGGWGAFDVNNEHHSLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGLDNQAVARAIGYLKRGQEVNGSWFGSWG
>T2AYQ6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWFGRWG
>T2B057|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIIIEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRVQEVNGSWYGRWG
>T2AZS4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWFGRWG
>T2B0F4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHISTEIETALNWLKKQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSESIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAITLLSLV
>T2AZ89|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQY
SNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFGSSDINNTHFYLS
EISSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGRWG
>T2B040|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTSLATHAMLEANLSSGPRILENDSTSKACKWLEKLQIKDCAGDWAVWRPNLRPGG
WAFQYHNDYYPDIDDTAVVAMALHRTGNKIYEPALLRAAEWIIGMQSKNGGWAAFDADNE
YHLLENMPFADHGALLDPPSVDVSARCISFLTQLGYDQTNGTIKRGIEYLKKNQEEDGSW
CGRWG
>T2AZ99|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTCIAQLALLESGVAPDDPMVQSSARWLMDKQIFAGGDWQVRAKDTRPGGWSFEFD
NLAYPDIDDASIVVMALERVRLPEAEEPRRADSIKRGVEWVAGMQCKNGGWAAFDKDNNK
KYLTKIPFSDFGETLDPPSVDVTAHLLEMYGRLGYTREEQAVDRGFEYVIGEQEENGSWF
GSWG
>T2AZ74|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
WDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQYSN
YYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYLNEI
PSADHGALLDPPTVDVTGRAITLLSLADKKIYAKNIKGGVDYIKSEQEEDGSWFGSWG
>T2AYG4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAICSNALLDSGLPTDHPALVRAGKWIVSKQVTKRGDWQVKNPKAEPGGWAFEFY
NELYPDTDDTAEILLFLNRVEILDNRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGKWGFNKQHPQVKRAIKFVKERQEVDGCWYGR
WG
>T2AYE9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPGLSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANRVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADEKIYEKNIDNGVDYIKSEQEEDGSWYGRW
G
>T2AYQ3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQY
SNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYLN
EIPSADHGALLDPPTVDVTGRAITLLSLADKKIYAKNIKGGVDYIKSEQEEDGSWYGRWG
>T2AZC2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGFNGLSLLESGLTLKDTPIQKACKWLEKKQILEIKGDWIVNNKNLLPGGWAFQY
ENDFYPDVDDTAVIVMFLDRAGYQNKKRLEIACNWIIGMQSKNGGWGAFDKDNTYHYLNN
IPFADHGALLDPPTADVSARCISMLSQINKKNYKKIIQKGVKFLKNEQENDGSWFGRWG
>T2AZQ3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVASMQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAITLLSLADKKIYEKNIKDGINYTKSEQEEDGSWYGRW
G
>T2B082|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLAMHAVFEANSEPDKIIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYLDVDDTAVVVMVLHRSDPDRYSEVIARGVEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPLTADVSVCCLSMMAQMGYGLDNQAVARAIRYLKRGQEANGFWFGSWG
>R9VYU6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAITAHSVLGHRDPKVHEAVAKGLEWLKPLQVLDVKGDWAEEKPNVRPGGWAFQY
RNDYYPDLDDTAVVVMALDRAQRTKAKTDYSQAIARGREWVEGLQSKNGGWGAFDADNSY
FYLNNIPFADHGALLDPPTEDVTGRCIGMLAQLGESSDTSRPLPRGVEYLERVQLKDGSW
FGRWGVNYIYGTWSALAGLNAAGLDPAHPMMRNAAAWLITIQNEDGGWGE
>R9W221|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAITAHSMCGSTKAVAIEASKAGLDWLVPKQVLDVRGDWIARRPDVRPGGWAFQY
ANPHYPDVDDTAVVAMAMDREQNLSGHKSYDPALARAREWIVGMQSENGAWGAFDADNEY
YYLNNIPFADHGALLDPPTEDVTARCLSMLAQFGDTLEGGEPMRHGVDYLRRTQLAEGSW
YGRWGMNYIYGTWSVLCALNAVGVDHDGAGSAKAAQWLLDIQNPDGGWGE
>A0A7K2GMP0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4934|TrEMBL
MTATTNGPAGAAPSRPAPARTTAATTDTAALDGAAVEAAAERARARAADHLLGLQSPEGW
WKGDLDTNVTMDAEDLLLRQFLGIRDEATTRSAALFIRGEQREDGTWATFHGGPPDLSTT
VEAYVALRLAGDSPDAPHMTRGAHWVRSQGGIAEARVFTRIWLALFGWWPWDRLPELPPE
LIFLPPWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPADPAPRARFAP
LASWNGAFQRLDRALHAYRKVAPRALRRAAMATAGRWIVERQENDGCWGGIQPPAVYSMI
ALHLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALADAGVPAD
HPQLVRAADWMLDEQIERPGDWSVRRPNLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVR
HPDTARMERAISLGVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDPPSADVT
AHVVEMLAAEGLAADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALVDAGLP
TTHPAIRRAVAWLESVQNDDGGWGEDLRSYREQGRMARGASTASQTGWALMALLAAGERE
SRAARRGVTFLAETQHEDGSWEEPYYTGTGFPWDFSINYHLYRQVFPLTALGRYTRGAAP
EGA
>A0A291QL30|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces formicae|TrEMBL
MTATTDGSTGAATPRAASASQPLDTTAATPGTRDAAARAIQRSTDFLLSRQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDEPTTRAAALFIRGEQRDDGTWATFYGGPGELSTTVEAY
VALRLAGDRPDEPHMVKASAWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELIYF
PKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHADARRPNPVKPLAPVASW
DGIFQRLDKALHVYHKVAPRRVRKAAMNSAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVLKAGLDSLDRFAVWRDDGARMIEACQSPVWDTCLATIALADAGVPADHPQL
VKAADWMLGEQIVRPGDWSVRRPGLTPGGWAFEFHNDNYPDIDDTAEVALALRRVKHPDK
ARMENAIERGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGRSHDPRTRRGIEWLLAEQEENGAWFGRWGVNYIYGTGSVVPALVTAGLPASHR
AIRRAVSWVESVQNDDGGWGEDLRSYRDRGWVGHGTSSASQTAWALLALLSAGEREAKSV
ERGIAWLAETQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPFTGGS
GKGS
>A0A6G2UJT3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4931|TrEMBL
MTATTDGSTGAANITGAPADDPTDTRTAANDVTDIARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPGDLSATIEAY
VALRLAGDRPDEPHMARASGWIRDQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFTLDELHTDPDHPNPPRKLAPPTSW
DGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMIEACQSPVWDTCLATIALADAGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARLEAAIARGVRWNLGMQSRNGAWGAFDADNTSAFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLAKHPRTREGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALITAGLPAGHP
AIRRAVDWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDTASV
TRGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFADRP
DAAEGV
>A0A6P0SWK0|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO2I5|TrEMBL
MQTQDRIVESGVTEAIANSQSYLLAQQYPDGYWWAELESNVTITAEIILLHKIWGTDKQR
PLHKAEAYLRSQQRKHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDSALVRARDFILR
RGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPEWFPFTIYEMSSWARGSTVPLLI
VFDQKPVFDIQPSINLDELYTEGADHAKFELPRNSDWTDLFVLLDDGFKLAEDWNLVPFR
KQGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPIVQRGLEAVDRFAIE
TPDSYRVQACVSPVWDTAWVLRGMVESGLDPDHPALVRGGEWLLQQQILDYGDWVVKNPQ
GKPGGWAFEFQNRFYPDLDDSPVVIMALNSL
>A0A5D4JNR1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces parvus|TrEMBL
MTATTDGSTGAANITGAPADDPTDTRTAANDVTDIARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPGDLSATIEAY
VALRLAGDRPDEPHMARASGWIRDQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPDHPNPPRKLAPPASW
DGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMIEACQSPVWDTCLATIALADAGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARLEAAIARGVRWNLGMQSRNGAWGAFDADNTSAFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLAKHPRTREGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALITAGLPPGHP
AIRRAVDWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAGGRRDTASV
TRGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFADRT
DAAEGV
>A0A6G4TRI5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces coryli|TrEMBL
MTATTQGSNGPARAEALKATAAAKDAPAVLTAADAARERAVGHLLSRQDAAGWWKGDLET
NVTMDAEDLLLRQFLGIGDDRTLAAAARWIRSQQLEDGTWNTFHGGPGDLSTTIEAYVAL
KLAGDDPDAPHMASAAQWVREQGGIAKSRVFTRIWLALFGWWKWDDLPELPPEVMYLPPW
FPLNIYQFGSWARQTIVPLTVVSAKRPVRQGPFPIDELHTDAAHPNPPQEPAPVNTWDGF
FQRLDKALHKYHKVAFRPLRKSALKKAAAWIVERQENDGCFGGIQPPAVYSIIALHLLGY
DLNHPVIKAGLQALDDFAIWPDEDTRMIEACQSPVWDTCLATIALADAGLPADHEALLRA
ADWMLDEQVTKPGGDWAVRRPQLASGGWAFEFENDTYPDTDDTAEVILALRRVEHPDPAR
VDAAVEKAVRWTAGMQSKNGAWGAFDADNTSVLPTKLPFCDFGEVIDPPSADVTAHVVEM
LAREGLANDPHARRGIAWLLAEQEPSGAWFGRWGVNYVYGTGSVVPALVEAGLPTSHPAI
RRAVSWLESVQNDDGGWGEDLRSYKYVKEWSGRGESTASQTAWALLALLAAGERESKATE
RGIEFLARTQNEDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVGSAGEAGEEA
GA
>A0A3A6PDF4|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus pinisoli|TrEMBL
MNELHNRVDQSIGQLADWLIGEQKEDGSWRFCFENGTIIDAYVLILFRLLEHEDEELLRQ
LHDRIAASQQPDGCWRLYHDEEKGSLSASIEAYYALLISGYSSAGDEHMQRAKAYILSRG
GIGMVRSTLTKTILAATGQREWPRSIAAIPMEIMLVPSELPLSLFSFSGYARVHLVPMLV
MGSRKYSLRTERTPDLSPLYANRDAEDESSFPSYIEMQKHIRAGMARLIGSPRSLADAAT
SKAEAFMLERIEGDGTLYSYATSTIFMIFALLALDYGKEHPVVRKACQGLADMRFHTEGI
TTIQNSPSDVWDTALISYALQEAGVSHRHDSILSASAFLLSRQHTRKGDWSKHNPNTPPG
GWGFSETNTMNPDVDDTSAALRAIHRLAVDEPVYAEAWHRGFRWALSMQNRDGGWPAFEK
ETNNQMLTWLAIEGAKSAAIDPSEADLTGRTLEFLGNFAGIQSNERFVKRGVDWLIRNQG
KNGSWYGRWGVCYLYGTWAALTGLAAAGLPPTHDALKNGAEWLLRMQQGDGGWGESCRSD
SSPHYISIGASTPSQTAWALDALIAVSPEATPAINRGVERLIAFLHERNWKTDYPTGAGL
PGYFYIHYHSYRYIWPLVALSHYKNKFGS
>A0A533Y153|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
MKRLLGLLTNWSEKILSVAPEHVQQQARQKAKRLLRLVGGTPNFFLSALGVQRPHNPGQV
SVQSVVAHKGDAVDKAIKRSQQWLLQRQTEAGYWVHELEADTTLTAEYLMLRRFLGLVDP
EKERKAVRYLIDAQVPEGGWPIYYGGPSEISASVKAYFALKLCGVSAAEPFMEKARTMIL
SKGGVVGANVFTKIALALFDQYDWRGIPSMPAEIVLLPPRFIFSLYALSYWSRTVLTPLL
IIFHYKPVCRIPKEQGIDELYCPAREWVDFRSEPPFRKDPSRFTWRNFFITLDGVLRFYE
RVVPQGLRKKAVARAAQWMIERMEGDGGLGAIYPAMANSVVALRCLGYAVDHLLVRKALH
GIEALEVHEGGAMHLQPCFSPVWDTPLTINALIESGLPQDHPALMKAARWTLSRQCRKVG
DWTVSSPKAEPGGWAFQFENEFYPDNDDTAVVVMALSKVRMPEWDAQRDGMRRGMRWTLA
MQGSDGGWGAYDKDNNKMFLNQIPFADHRALLDPSTADLTGRELEMLGALGFDMKHPAAV
RALRFLRKNQEADGSWYGRWGVNYVYGTWSVLAGANAIGEDMQAAYVRRAVAWLVSKQNP
DGGWGESCLSYAEADAHGVGESTPSQTAWALLALLCAGEVDSLSVLRGVNYLLRQQDAQG
YWPERKHTGTGFPRVFYLRYHGYCQYFPLWALSMYRSLKARGRSRADEIREQNRQHGRFR
FEA
>A0A5B9EJF4|squalene-hopene cyclase|EC 5.4.99.17|Terriglobus albidus|TrEMBL
MREQFGSAVPAIVSVGSLELDQQNEELSQQSITQLEQQLSLTAEALLRKQHADGYWCGDL
TADSTLASDYVLLQLWLFPPEEGGAWTPPCAQRTAKLVRYLKACQLADGGWNLFAQGEAD
VNATVKAYTALKIMGEDVDSRCMRAARERILELGGLQACNSYTKINLSLFGLFPREFVPT
VPAEIMIVPGSFLYEMSSWTRTIIVPLSIIQGLGAQRTAPSGMTLQELIYPGSPITMPRK
DLTSELFLHADKLLKHWERRGVQKIRGRAIAAAERWMLEHLQHSEGLGAIYPSMMYAIMA
MDSLGYERDQPDMIEAIRHFDELLLEREDVIEFQPCKSPVWDTAIAAFALGETGDIDTES
MTRAADWLLSKEVRRKGDWSAKRPNLRPSGWAFEFANDFYPDIDDTAMVLLALQHIRASN
PGRQARAEQRAIDWLLGMQSADGGWAAFDVDNDWQLLNKVPFADHNAMLDPTCADITGRV
LEALSKRGLGPKHPAIVKGVQYLLSSQEQNGSWYGRWGVNYVYGTFLAMRGLIATGDSRA
HSAVEKAARWLLSVQNKDGGWGESCVSYEVDRFVAAESTPTQTAWALVGLMASGKGRSSQ
VQRGIEWLLENQRADGDWDEALTTGTGFPNVFYLSYHLYRMYFPALALATYRRELMRAPM
RMQATI
>A0A7Y6JXH6|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia youngii|TrEMBL
MNDLSQTQPLDAVLPEAADAAPNLAEAAVVANAPAVADALATATPSAMQTAGASPLDASI
TRATDAILAAQQPDGHWIYELEADATIPAEYVLLVHYLGETPNLELEQKIARYLRRIQLP
NGGWPLFTDGALDISASVKAYFALKMIGDPVDAEHMVRARDAILAHGGAEHANVFTRILL
ALFGVVSWRAVPMMPVEIMLLPMWFPFHLSKVSYWARTVIVPLLVLNAKRPLARNPRKVR
IDELFRGAPVNTGMNERAPHQHAGWFGFFRCVDTVLRAVDGLLPKASRERAIRAAVAFVD
ERLNGEDGLGAIFPAMANSVMMYDVLGYPADHPNRAIARKSLDKLLVIKDDEAYCQPCLS
PVWDTSLAAHALLETREARAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYN
NAHYPDVDDTAVVVMAMHRSAALTKSDVDREAIARAREWVVGMQSSEGGWGAFEPENTQY
YLNNIPFSDHAALLDPPTADVSGRCLSMFAQIGELPQNSEPAQRAFDYMLQEQESDGSWY
GRWGLNYIYGTWTALCSLNAAGMSHDDPRMRRAVQWLVSIQNEDGGWGEGGESYKLDYRG
YERAPSTASQTAWALLGLMAAGEVDHDAVARGIDYLQREQREHGLWDETRFTATGFPRVF
YLRYHGYRKFFPLWALARFRHLKRNGLTRVTVGM
>A0A5C8C705|squalene-hopene cyclase|EC 5.4.99.17|Afipia sp|TrEMBL
MTLLDDHRAAAAPSAPALENSIAAASSAILDARKADGHWVFELEADATIPAEYVLLRHYL
AEPVDSVLEAKIGNYLRRIQNDNGGWSLFYGHEFDMSASVKAYFALKMIGDKPDAPHMKK
AREEILRRGGAIKSNVFTRIMLALFGVVTWRAAPMMPVEIMLLPRWFPFHLTKISYWART
VIVPLLVLMNKKPRARNPLGIGIDELFLEDPKSIGMTAKAPHQSQLWFTAFDLLDKVLRI
VDPLFPKAPRQRAIDKAVAFVTERLNGVDGLGAIFPAMANTVMVYDLLGYPKDHPHYVLA
RQSVENLLVIKDDEAYCQPCVSPIWDTALTAHTMIEVGGEKAEASAKAALDWLKPKQVLD
VEGDWIEKRPGVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRARGTLNAGEKYDEAIARGR
EWIDGLQSKDGGWAAFDADNLEYYLNNIPFSDHGALLDPPTEDVTARCVSMLAQLGETIQ
TSAPLARGVEYLRRTQLADGSWFGRWGVNYIYGTWSVLCALNAAGVDHNDPVIAKGADWL
ISIQNPDGGWGEDGNSYKLEYRGYERSDSTASQTAWATLALMAAGKVDHPAVQRGIAYLI
QFQGKDGLWTEPQYTGGGFPRVFYLRYHGYSKFFPLWALARYRNLRNTNSRFVGIGM
>A0A5D4RHT0|squalene-hopene cyclase|EC 5.4.99.17|Bacillus infantis|TrEMBL
MKNRNKGAGCMQLVKSEIERLKQQLLSEQTPDGSWNHPFDTGCMTDIYMIVLLRTLEEED
EEELIKELAKGILSRQGKDGAWRLFHDHHEGSLSLTIEAYYALLYSGYYEKNHPALVRAR
RFITKGGGLKKAGMYTKIMLALTGQYPWPLLFPVPMEVILLPGSFPLNMYDISVFGRSNL
IPVILLGNKKFSRKTALSPDLGDLSVRDDDDPWPELRSAEWRSLTSFLAAGVKALVGIPR
QIRAWSIEKAREYMQSHTEPDGTLYNYFSSTFYMIFALLALGGGPEEPAIKNAVAGLKRM
TVKTDGRTHIQYTTAAVWNTALISHALQEAGVPPKEDAIQKANQYLAGQQHRRFGDWIVH
NSKAEPGGWGFSRFNTINPDVDDTTAALRSLHQPAREKAHYEEIWKKGLLWTLSMQNRDG
GWPAFERNVDKKLLHLLPIQGAEFILTDPSTADLTGRTLEFLGKAGYSDSSLPPIKKAVK
WLRKHQEPNGSWYGRWGICYIYGTWAAVTGMAAVGVTLEDKSMKKGIDWLVSIQNEDGGW
GESCRSDMEKKYIPLKESTLTQTAWAVDALAAAGMADSTPARKGAAFLVREGKRKDWTAD
YPMGQGMANFFYIHYHSYRSIWPLLALSHYIEKSEALV
>A0A662ETC8|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Acetothermia bacterium|TrEMBL
KRSAWGRFFTFADKVLRVHEHSRWKPLRERAIKAAEEWIIARQEADGSWGGIQPPWVYSL
IALKALGYPIDHPVVEKGISGFYGEKGFAIEEDDTFRLQSCLSPVWDTGLAMIALQDAGL
PADHPALVKAGKWLLNEQIFVGGDWQVKCNGRPGGWAFEFDNDVYPDTDDSSVVMMALLR
TDLPKRAKEFAISRGLEWLLAMQSSNGGWGAFDRNNTRAFLREIPFADFGEMIDPPSVDV
TAHIVELLGRLGYKKGFRPVDRALRYLKREQEPDGAWYGRWGVNLTYGIGYVLPALAAVG
EDMRAPYVRRAVEWLISHQNADGGWGERIEGYYDPAWRGRGPSTASQTAWAILALIAAGE
IDRPATVRGISYLIETQKEDGGWDEPYFTGAGFPTDFMINYHFYRDVFPVMALGRYRRGR
EEG
>A0A8G0XWL2|squalene-hopene cyclase|EC 5.4.99.17|Ruficoccus sp. ZRK36|TrEMBL
MTLSLDQGIRGALDWLAREQKSEGFWNDVLESNCCMEAQWVLAMHFLERTDDPKYDKIIK
GIIHKQREDGSWDIYYGAELGDINTTIECYAALRSAGMGPDEEPTRLAREWILSHGGMQK
ARMFTRFWLATIGEWPWETLPVIPPEIIRIPLWAPFNIYQFAQWARATFMSMSIVSVRRP
VVPLAPERRLDELYPEGRENFDFSFPKRLSGFWPTFFRTADKVLHFWQGLPWKPGRENSI
KLALEWVIKHQDADGAWGGIQPPWIYALLALHTEGYNREHPVMAAGINAWNNHWSYERDG
MIFIQASESPIWDTMLAMQAILDCGETWESYPPLKDALEYILDKQVLCKGDWAMTVKGVE
CGGWAFERANTFYPDLDDTAVALTVLCQMKELAPESYRARIDRAFDRAEAWLRAMQSTNG
GWGAFDKDNHTKALTQIPFCDFGEVLDPPSADLTGHKLEALGLMGYGMEDPAVKRGVDYI
MAEQEPEGPWFGRWGVNYIYGTALVLPGLKAVGFDMHDPRIRKCAQWLLERQNEDGGWGE
SCGSYMDDSLRGVGTTTPSQTGWALMALLAMDTHEYDAAIQRGLDYLLRTQKDGTWEQLE
YTGTGFPGYGVGERIRLAGNTDALSQGRELARGFMINYNMYRHYFPLMAMGRARRHLADQ
A
>A0A7V1YM52|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MRSERGLREAARRARARAVELLLSLQDDGGWWKGELETNVTIEAEDLLLREFLGIRREEE
TRLTANWIRRRQRADGTWATFEGGPGDLSTTVEAYVALRLAGDPPEAEHMRRAAAFVRAQ
GGLERARVFTHLWLALFGLWPWEDVPALPPELVLLPPRVPLNVYDFACWARQTIVALSVV
WAHRPVHPLPFDVDELHAGRRADPPPRSIPARAFRRLDRLLHRYERRPVGPLRRVALARA
LEWIVRRQEADGSWGGIQPPWVYSLIALRASGYPLDHPVLRRGLEGLDRFTIVEGELRRI
EACQSPVWDTALAVQALADAGLPADHPALVRAADWLLDQQVKVPGDWAVRRPGLEPGGWA
FEFENDTYPDIDDTAEVVLALRRVRHPDPARVDEAVRRAVGWVLGMQSSDGGWGAFDADN
TRALCREIPFCDFGEVIDPPSADVTAHVVEMLAGEGRASDPAVRRALGWLAHHQEPDGSW
FGRWGANHVYGTGAVVPAAIAAGIPPPDPRIRAAVRWLERHQGADGGWGEDLRSYRDPSW
IGRGRPTPSQTAWALLALLAAGEGSEAVERGVAWLVETQGPDGGWDEPLYTGTGFPGDFY
INYHLYRLVFPAMALGRYLGRER
>A0A538HVM4|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MTSVADPPVVDAAVSAALDRAVGRLLSLQNERGWWKGELETNVSMDAEDLLLRQFLGIRT
DEQTRLSAQWIRSQQRDDGTWGTFFGGPPDHSVTIEAYAALRLAGDPPDAEHMRRAREYV
LDQGGIERSRVFTKIWFSLFGLWSWEHVPAMPPELIFLPPWAPLNLYDFACWARQTVAAL
TVVWAYRPVREIPISLDELRVGGPPQSRFPVTDPVSRGFVALDRALHAYERRPVGALRKR
ALRKVERWILEHQEPDGCWGGIQPPWVYSIMALTLRGYPLEHPIVKRAIDGLDGFTTVDE
KGRRLEACQSPVWDTCLALIALSDAGLPADHRALDRAARWLVTEEITIHGDWAVRKPDLA
PGGWAFEFENDWYPDIDDTAEVVMALRRVEQDADIAGAAARGAAWTLGMQSRNGAWGAFD
ADNTRTLVGRLPFCDFGEVTDPPSVDVTAHVVEMLAKDGMTHHPAVQRGIEYLLREQEAD
GSWFGRWGANFVYGTGAAVPALVEAGISPDHESVRRAVAWLERVQNDDGGWGEDLRSYVD
RTWSGQGESTASQTAWALLALHAAGEHGDSVTRGLDWLVRTQLPDGGWDEPWFTGTGFPG
DFYINYHLYRLVFPVSALGRYVHGGRA
>A0A846CNU3|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO2C4|TrEMBL
MQTQDRIVESGVTGAIANSQSYLLAQQYPDGYWWAELESNVTITAEIVLLHKIWGTDKQR
PLHKAEAYLRSQQQKHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDSALVRARDFILR
RGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPEWFPFTIYEMSSWARGSTVPLLI
VFDQKPVFEIEPRINLDELYTEGADQVKFELPRNSDWTDLFVLLDDGFKLAEDWNLVPFR
KQGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPIVQRGLEAIDRFAIE
TPDSYRVQACVSPVWDTAWVLRAMVESGLEPDHPALVRGGEWLLQQQILDYGDWVVKNPQ
GKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLKQAAMARGLAWIASMQCNQGGW
AAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEMLGSCNLSIESQKLENAIAFLIQ
EQEADGSWFGRWGVNYIYGTSSALSALSKIAPHTHQRSIERGAAWLVKCQNLNGGWGETC
LSYDDPTLKGLGISTASQTAWALIGLMAAGEATGNWAMDAIEMGVNYLVSTQQPDGSWDE
TEFTGTGFPSHFYLKYHFYQQYFPLLALGRYQISISS
>A0A8J7JM02|squalene-hopene cyclase|EC 5.4.99.17|Nodosilinea sp. LEGE 07088|TrEMBL
MQTQEPQQVTGLERAIREAIPARIAAAQNYLLALQHRDGYWWAELESNVTITAEIILLHK
IWGTDGERPLAKAETYLRSHQRDHGGWELFYGDGGDLSTSVEAYLALRVLGVPASDPALL
KAKSFILGRGGITQTRIFTKLHLALLGCYDWRGLPSLPAWVMLLQSPSPFTIYELSSWAR
GSTVPLLIVFDQKPVYAIEPAVTLDELYAEGIANVRWELPKAGDWSDLFVWLDGAFKWAE
SINFTPFRQEGLRQAERWILERQEATGDWGGIIPAMLNSMLALRGLGYDVNDPVVRRGLR
ALDNFAVETDDTYWVQACVSPVWDTALAMRSLTDSGLAPDHPALVQAGEWLLDKQILDYG
DWVVKNPQGQPGGWAFEFDNRFYPDVDDTAVVAMALQDVTLPDEALKREAIARAVRWVAT
MQCKTGGWAAFDIDNDQDWLNAIPYGDLKAMIDPSTADITARVLEMHGRLLRQPDLAARY
ASDLTAQRLERGLAYLLHEQEADGSWFGRWGVNYLYGTSGALSALALVAPGREQGAIPPG
IATRIARGAAWLVRCQNPDGGWGETCRSYDDPSLKGQGPSTPSQTAWALLGLIDAAECGA
ATETQAIQRGIDYLLSTQTAEGTWAEQEFTGTGFPGHFYIRYHLYRHHFPLMALGRYQSW
QGMRSR
>A0A3N9FWX2|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cenocepacia|TrEMBL
MNDLTEMATLSAGAVPAGVDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKALDKLLVVHDDEAYCQPCLSPVWDTSLVAHALLETGDARAEEAVLRGLEWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLKQSDTYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRAAQWL
LSIQNKDGGWGEDGDSYKLNYRGYEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLV
AQQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRTNATRVTVGM
>U5DMF8|squalene-hopene cyclase|EC 5.4.99.17|Rubidibacter lacunae KORDI 51-2|TrEMBL
MQLHSEVGLDRLDRAVAASQRYLLSHQYPEGYWWAELESNVTITVEVLLLHKIWGTDTVR
PLHKIEAYLRQQQRESGGWELFYGDGGSLSTSVEAYLGLRLLGVPAGDPALVKARTFILE
RGGISKTRIFTKFHLALVGCYNWRGLPSIPPWIVFCNPPFPFSIYEMSSWARGSTVPLAI
VFDKKPVYPVEPSVKLDELFAEGSANVRYELPRNNDWSDAFVWLDNAFKLAEDWNLVPLR
QEGLKAAERWVIERQEVTGDWGGIIPAMLNSMLALRSLDYSVDDPIVVRGFQAIDNFVLE
DDEVYRVQPCISPVWDTAWVVRALVDSGMASDAPELVAAGRWLLERQILDYGDWRVKNPQ
GEPGGWAFEFDNRFYPDVDDTAVVVMALEQLRLPEEALKRQAIVRATQWVATMQCRAGGW
AAFDIDNDSDWLNLLPYSDLKATIDPNTADVTARVLEMIGYLDPQQPGIARERCDRALDY
LLDEQEPEGCWFGRWGVNYIYGTSGALSALALVAPQHARDAIERGAAWLLGVQNPDGGWG
ETCRSYEDPTLKGKGVSTASQTAWALIGLLAAGDATGSYAQQFIVRGVEYLIGSQLENGR
WEEAEFTGTGFPEHFFLRYHYYYQYFPLIALGRTRQIFAGRT
>A0A4Q0RF05|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium guangzhouense|TrEMBL
MDSVTATSREALESSIASATQGVLGLQQSDGHWVFELEADCTIPAEYILLRHYLAEPVDT
ALEAKIANYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDSVDAPHMLRAREAIH
ARGGAIHSNVFTRFLLATFGVLTWRAVPVLPIEIVLLPFWSPFHLNKISYWARTTMVPLM
VIAALKPRAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFLLFRSLDAVLRVVEPMFP
KSLRKRAIDAALAFIEERLNGEDGMGAIYPPMANIVMMYDALGKDENFPPRAITRRGIDK
LLVIKGDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLDWLIPKQELAVKGDWA
VKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGAAGYDAAIDRGREWIEGMQ
SDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLGQLGETEATSKHVAA
GVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGISHDDPMMRKAAAWLASIQNKD
GGWGEDAVSYRLDYRGWEPAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIATQSEKG
LWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A7Y4W0T9|squalene-hopene cyclase|EC 5.4.99.17|Methylococcaceae bacterium|TrEMBL
MFTDANSDNHFSHSVSSSSTIHTKAYDLDRAISKAQDKLLSLQSPEGFWVFDLEADCTIP
SEYIMMMHYLGEIDEPIQAKIANYLRSRQSEDGSYPLFTGGPGDISGSVKVYYALKMAGD
SIDAPHMTRLRTYILSQGGAAKANVFARITLAIFEQLPWRGVPYIPVEIMLLPKWFPFHL
DKVSYWSRTVMVPLFILCTLQATAKNPNKIEILELFVTHPDEEKHYFPERTLLNKIFLGL
DKLGRITQPLIPKKMRAKALESAKDWMVERLNGEDGLGCIFPAMVNAYAALLLLDFPKDH
DYVVTARKAIDKLLVINEHDAFCQPCVSPVWDTGLAALALQEADVSANSKSLTRAYDWLK
SKQLSDEPGDWRIARPNLAGGGWAFQYANPHYPDVDDTAVVAFAMADSMLPNLEESVQRA
ALWIEGMQSKNGGYGAFDVDNTYYYLNEIPFADHGALLDPPTSDVSARCAMLLARIVDTH
EQYIPALERTINYLRSEQEADGSWFGRWGTNYIYGTWSVLLGLEQTNLPKTDIMYVKAAK
WLKSVQREDGGWGEDNYSYHDLSASGKYRFSTAFQTAWAVLGLIAAGEVHSSAVKAGIDF
LLRTQQTDGVWNDKCFTAPGFPKVFYLKYHGYDKFFPLWALARYRNELNKK
>A0A7W9UGX2|squalene-hopene cyclase|EC 5.4.99.17|Nocardia transvalensis|TrEMBL
MTVIDTATTATDDLASVHDALHAAVAHLRGLQDDNGWWKGELATNVTMDAEDLLLREFLG
ISTPRVTEPAARWIRSQQREDGTWATFHGGPGDLSTTVEAWVALRLAGDSPAAPHMRAAA
DFVRAGGGVEASRVFTRIWLALFGLWSWDDLPNLPPELVFLPPWFPLNVYDWGCWARQTV
VPLTVVATLRPVRPLPFGIDELRAGSPAPQRDSLFSVSGAFQRLDTVLHGYARRPLGWVR
DLAMRQAAEWILARQEADGGWGGIQPPWVYSLLALHLLGYSLDHPAVRAGLDGLEGFVVH
EQTPDGEVRRLEACQSPVWDTALAVTALLDAGVPGDDPAVLRAADWLLDEQITAGGDWQV
RRPDLTPGGWAFEFANDGYPDTDDSSLIVLALNRVAHPDPARLRAAVERGAEWTTGMQSA
DGGWGAFDADNTSKLPLALPFCDFGAVTDPPSADVTAHVVEMLAALGRASGDECRRGVRW
LLAHQERDGSWFGRWGANHVYGTGAVVPALIAAGVDRRSRHIRAAVRWLRIHQNRDGGWG
EDLRSYRDATWIGRGESTASQTAWALLALLAADADRAVIDRGIRWLVGTQRPDGGWDEDL
FTGTGFPGDFYINYHLYRLVFPIWALGRYLSREDG
>A0A7S8HD86|squalene-hopene cyclase|EC 5.4.99.17|Kaustia mangrovi|TrEMBL
MVSIAETFRGAFGGRRKRATAGETPAQPAPAVETTSRPKSLLDEVEATVEETSRALAGRQ
KDDGHIVYELEADATIPAEYIFLNHFLGEPEPELEAELGEYLRSIQSDRHGGWPLFHDGD
FNISASVKAYYALKIVGDDPDAPHMKRAREAILAHGGAETSNVFTRYALALFGEVPWRAV
PVMPAELMLMPRWFPVNMWRFSYWSRTVIAPLLILAALKPRAKNPTGAHCQEIFRTPPEK
IRKWLTNPTGSRWGSFFLALDKVLQPTEKHVFPRLPTRAKSIQAALDFIKPRLNGEDGLG
AIFPAMANSVMAFTALGYPKDDPDLVTARQSIRNLLVAAREERDGEPRYCQPCVSPVWDT
ALAAHALSESGEDSTPSVKAACDWLVDRQITDVKGDWAINAPDLEPGGWAFQYNNDHYPD
VDDTAVVGMLLHRTDPEGYKDRIERAARWIEGMQSSNGGWGAFDIDNNADFLNSIPFADH
GALLDPPTSDVAARCLSFLAQIGYSRTHPTVARGVHFLKTEQEEDGSWFGRWGTNYIYGT
WSVLCALNAVGEDMSAPYVRKAVDWLHSRQREDGGWGEDGATYWQERRDETKASTPSQTA
WAVLALMAAGEVDSEPVERGIRYLLSQPRKNEKWEEPWFTAVGFPRVFYLRYHGYSAFFP
VWALSRYRNLKRGNSREVAWGM
>A0A6G2R682|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4951|TrEMBL
MTATTDGSTGALPPRAPSASDATAENTAPPAATRTAVRQDTVDAARRATARATDYLLSVQ
DPAGWWKGDLETNVTMDAEDLLLRQFLGIQDPELTEAAARHIRKEQCADGTWATFYGGPG
ELSATIEAYVALRLAGDAPDAPHMAKAAAWVRGQGGIAAARVFTRIWLALFGWWKWDDLP
ELPPELLYFPKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPRRPNPP
RPLAPATSWDGVFQRLDKALHLYHKVAFRKLRAAAMRSAARWIIERQENDGCWGGIQPPA
VYSIIALHLCGYDLDHPVLRTGLASLDRFAVWREDGPPGPDGPGGAPTRMIEACQSPVWD
TCLATIALADAGLPADHPQLVKAAEWMLAEQIDRPGDWSVKRPQLPSGGWGFEFENDNYP
DIDDTAEVVLALRRVRHPDPLRVEAAVRRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLP
FCDFGEVIDPPSADVTAHVVEMLADVGRTHDPRTRRGIAWLLAEQETGGAWFGRWGTNYL
YGTGSVLPALAAAGVPASHPAVRRAVGWLERVQNDDGGWGEDQRSYQDKEKWAGRGASTA
SQTAWALMALLAAGERGSEAVRRGVHWLTATQREDGSWDEPYFTGTGFPWDFSINYHLYR
QVFPLTALGRYLNGGPAGAPVGA
>Q3SQB8|squalene-hopene cyclase|EC 5.4.99.17|Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255)|TrEMBL
MNSINATAAPIDDNVLGDRIGAATRGLLSLKQSDGHFVFELEADATIPSEYILMRHYLGE
PVDTVLEAKIAAYLRRIQGAHGGWPLVHDGPFDMSASVKAYFALKMAGDSIDAPHMARAR
EAILSRGGAANVNVFTRFLLSFFGELTWRSVPVLPVEIMLLPMWSPFHLNKVSYWARTTM
VPLMVLAALKPRARNPRGIGIRELFLEDPATVGTPKRAPHQSPGWFALFTGFDRVLRLIE
PLSPKWLRARAMKKAIAFVEERLNGEDGLGAIFPPMVNTVMMYDALGFPPEHPPRAVTRR
GIDKLLVVGENEAYCQPCVSPIWDTALSCHALLEAGGPEAVNSAGKCLDWLLLKQELVLK
GDWAVKRPDVRPGGWAFQYANGHYPDLDDTAVVVMAMDRVRRNGPNGRYDEAIARGREWI
EGMQSRDGGFAAFDADNLEYYLNNIPFSDHAALLDPPTEDVTARCVSMLAQLGETVDSSS
SMAAGVEYLRRTQLAEGSWYGRWGLNYIYGTWSVLCALNVAGVDHQDPVIRRAVNWLVSI
QNADGGWGEDAVSYRLDYKGFEGAPTTASQTAWALLALMAAGEVENPAVARGIKYLIDTQ
TKKGLWDEQRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNSKAVGVGM
>A0A3A4WZJ8|squalene-hopene cyclase|EC 5.4.99.17|Desulfobacteraceae bacterium|TrEMBL
MCALWLKRSPESNSFKIDRGIEAAIKWLELRQQPEGFWVGMLESNSCMEAEWILAMHFLG
VADDPKYSKVVRSILNEQRPDGSWQTYYDAPQGDINTTVECYAALRAAGLHPDFEPLKRA
RKWILESGRLNRIRVFTRFWLALIGEWPWEDPPSCPPELIFLPPYFFLNIYEFASWARAT
IIPLCILSALRPVRPLPPAARLDELFPHGRRNAAVAPPFVAGFFTWKSFFRGIDRLLKAY
THFPWQPGRRLARKRCAAWIVEHQDEDGAWGGIQPPWIYSLMALKTQGFPIDHPVIEKGL
RAFDAPWSYEKKGGIHLQASESPVWDTLLVLDSMLDCGSNPEAAPVMRSAIEWILEKQIT
ASGDWAIKVKDVCCGGWAFERANLFYPDIDDTAIAIIVLARARNFFKGPSKIDRALRLAT
EWMLAMQCANGGWAAFDRNNTNTWVTKLPFLDFGEALDPPSADVTAHVVEALGATGRRMN
DPAVRSAVRFIRDEQEPEGSWFGRWGVNHIYGTAAVLPALAAVGEDMEASYVRKAADWIA
GRQNPDGGWGETCASYMDDRLKGVGPSTASQTGWALIALLSVDTRRYDGIVLCGVDYLLS
TQKEGTWDEPYYTGTGFPGYGVGARADLKRKGSTLEQGTELSRGFMINYNLYRHYFPLMA
LGRARRHFGKR
>A0A7W1P1Y3|squalene-hopene cyclase|EC 5.4.99.17|Chthoniobacterales bacterium|TrEMBL
MPRSSSNVIPLPSALPEAAATDGFQSDALAKAIERAQENLLRQQHRDGHWCGELLVDSTL
CSDYVLFMHWLGDVDDALQQRCVRHILKRQLPDGGWNIYYGGSSEVNASVKAYFALKLAG
HSADLPFMQEARANILRLGGIPKMNTFSKLYLALLGQFPWHYLPSIPVEMILLPDWAPFN
IYKMSSWSRAMLVPLAIINHFKPTRELPGLQQLHELYPLGTEHKDFTLPRDPRFFAWRNL
FLRCDRALKLVSKVGWRPMRQRALEEAERWMLERIGPGSDGLAAVFPAMLNAMIALRALG
YPATHPMFVKAAEDFKGLFVDDPDDFRIQPCLSPVWDTAINMIALAESGLPAEHSALQKA
ADWLLSKEVRVPGDWARNNQHTEASGWAFEYNNVYYPDTDDTAMVLMGLRVARPDEPERF
QEVFKRAIAWQLSFQCADGGWAAFDKEVTQHWLEDMPFADHNAILDPTCSDLTARTLELF
GYIGFDVKQRCVRRAVQYLVDTQDDDGSWYGRWGVNYIYGTWQVLRGLRAIEEDMTQDWI
LRGRDWLESCQNPDGGWGETCASYDDPTMKGKGDSTASQTAWALMGICACGDLERSSVRR
GIRYLLTTQRMDGAWDEPQITGTGFPGVFYLRYDMYRQNFPLLALATFVNYRRGAQHPPS
FFRC
>A0A838FN26|squalene-hopene cyclase|EC 5.4.99.17|Chthoniobacterales bacterium|TrEMBL
MPPAPSNVIPLPSASPDTSAAYAPSSGDLSDSIARAQANLLRQQHPDGHWCGELIVDSTL
CSDYVLFMHWLGQVDETLQQRCVRHILERQLPDGGWNIYYGGPSEVNASVKAYFALKLAG
HSADLPFMQEARANILRLGGIPRMNTYSKLYLALLGQFPWHYLPSIPVEMILLPNWAPFH
IYKMSSWSRAMLIPLAIINHFKPTRDLPEAQQLHELYPLGTEDKNFTLPRDRRFFAWRNF
FLRCDRALKLISKVGWRPMRKRALEEAERWMLERIGEGSDGLAAVFPAMLNALIAMRALG
YPETHPAYQKALADFRGLFVDDPEDFRIQPCLSPVWDTAINMISLAEAGLPADHPALRKA
AEWLVSKEVRLRGDWTVDNPGVEASGWAFEYNNVYYPDTDDTAMVLMGLRLAKPEKTEEL
EQLFRRALDWQLSFQCRDGGWAAFDKEVTQHWLEDMPFADHNAILDPTCSDLTARTLELF
GYIGFDVKQPCVRRAVQYLIDTQEDDGSWYGRWGVNYIYGTWQVLRGLRAIDEDMSQDWI
LRGRDWLESCQNDDGGWGESPVTYETPVLKGKGESTASQTAWALMGILACGDLDRPSVQR
GLRYLLSTQNRDGAWDEPQITGTGFPGVFYLKYDMYRQNFPLLALATYVNYRRGTFHPPS
HYRCG
>A0A7S7TZU9|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. CCBAU 53421|TrEMBL
MLSRDHGVAVDPVALEKSISKATEALLGYRQSDGHWVFELEADSTIPAEYILLRHYLAEP
IDAALEAKLGNYLRRVQGAHGGWPLVHDGPFDMSASVKSYFALKMIGDSVDAPHMVRARE
AIRSRGGASGSNVFTRFLLALYGVVTWRATPVLPIEIMLLPMWSPFHINKISYWARTTMV
PLMVLAALKPRAKNPKGVGIDELFLEDPKSVRMAPKAPHQSASWFYLFRSLDAVLRVIEP
MFPKRLRQRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKDENFPPRAITRRG
IDKLLVVGEHEAYCQPCVSPVWDTALTCHALQEAGGDDTLAKAKQGLDWLKPRQVLELKG
DWAVKAPDVRPGGWAFQYNNDHYPDLDDTAVVVMAMDRVRRHTGTREYDEAIARGREWIE
GLQSRDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLGQLGETAVSSKA
MADGIAYLRRTQLAEGSWYGRWGLNYVYGTWSVLSALNVAGVDRNDPMIRKAVDWLSSVQ
NQDGGWGEDAVSYRLDYKGYEVAPSTSSQTAWALLGLMAAGEVENPAVARGVEYLKATQT
EKGLWDEQRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNSRVVGVGM
>A0A850JAS1|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. BRA 177|TrEMBL
MTTLETPETPETAPARTAAEALEAARDHLLLLQSPEGWWKGELQTNVTMDAEDLLLREFL
GIRTDEDTYEAARWIRSQQAPDGTWANFHDGPPDLSTTVEAYVALRLAGDLPDAGHMIRA
AAYIRSEGGVPAARVFTRFWLAMFGRWSWDELPVVPPEMMFLPRWFPLNVYDFACWARQT
IVPLTVVGAVRPVRPLPFGLDELVPDYDIPRAKRRRTPGWGEAFGALDKALHLYQRRPVK
GLRDAALRRAAEWIVARQERDGSWGGIQPPWVYSLLALHLLGYGLDHPVMQRGLDGLERF
TIRDEQGRRLEACQSPVWDTVLAMNALADAGLPAGHPALERAAEWVIGEEVKGPGDWSVR
RPGLPPGGWAFEFDNDVYPDVDDTAEVVIALDRVQHPRAEPAIERGVRWMAGMVSKDGGF
GAFDVDNTRALCRKLPFCDFGEVIDPPSADVTAHVVEALAHRGMADSLLAKRAVVWLLKA
QEPDGSWFGRWGANHVYGTGSVVPALIAAGVRPEKPVIRDAVGWLERHQRDDGGWGEDLR
SYRDRSWVGHGASTASQTAWALLALLAAGERGPAVERGVRWLTERQRPDGTWDEDHFTGT
GFPGDFYINYHLYRLVFPLSALGRYLRGA
>A0A7T4N7A1|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia ginsengisoli|TrEMBL
MNDLSQAQPLDDVLPETADAAPNVSADGQHALAVETQANAVAPVVSTASLDAAITRATDA
ILAAQQPDGHWVYELEADATIPAEYVLLVHYLGETPNLELEQKIARYLRRIQLPNGGWPL
FTDGALDISASVKAYFALKMIGDPADAEHMVRARDAILAHGGAENVNVFTRILLALFGVV
SWRAVPMMPVEIMLLPMWFPFHLSKVSYWARTVIVPLLVLNAKRPLARNPRKVRIDELFR
GAPVNTGMNDRAPHQHAGWFGFFRGVDTLLRGVDGLFPKATRERAVRAAVAFVDERLNGE
DGLGAIFPAMANSVMMYDVLGYPADHPNRAIARRSIDKLLVIKDDEAYCQPCLSPVWDTS
LVAHALLETGEAHAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYNNAHYPD
VDDTAVVVMAMQRSAALTQSTVDRDAIARAREWVLGMQSSDGGWGAFEPENTQYYLNNIP
FSDHGALLDPPTADVSGRCLSMLAQLGELPQSSEPAQRAFAYMLQEQESDGSWYGRWGLN
YIYGTWTALCSLNAAGMPHDDPRIRRAAQWLLSIQNPDGGWGEGGESYKLDYRGYERAPS
TASQTAWALMGLMAAGEVNHEAVARGVDYLQHEQREHGLWDETRFTATGFPRVFYLRYHG
YRKFFPLWALARFRHLKRNGLTRVAVGM
>A0A7W8S8B2|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia sp. CI2|TrEMBL
MNDLSHTQPLDAALPEAADAAPDLAEAAVVANAPAVADALATATPAPVQGGNALDASITR
ATDAILAAQQPDGHWVYELEADATIPAEYVLLVHYLGETPNLELEQKIARYLRRIQLPNG
GWPLFTDGALDISASVKAYFALKMIGDPVDAEHMVRARDAILAHGGAEHVNVFTRILLAL
FGVVSWRAVPMMPVEIMLLPVWFPFHLSKVSYWARTVIVPLLVLNAKRPLARNPRKVRID
ELFRGAPVNTGMNERAPHQHAGWFGLFRCVDSVLRAVDGLLPKATRERAIRAAVAFVDER
LNGEDGLGAIFPAMANSVMMYDGLGYPADHPHRAIARNSLDKLLVIKDDEAYCQPCLSPV
WDTSLAAHALLETGEARAEQAAERGLAWLRPLQILDVRGDWISRRPKVRPGGWAFQYNNA
HFPDVDDTAVVAMAMHRSAALTQSDVDREAIARAREWVVGMQSSDGGWGAFEPENTQYYL
NNIPFSDHGALLDPPTADVSGRCLSMFAQIGELPQSSEPARRAFDYMLQEQESDGSWYGR
WGLNYIYGTWTALCSLNAAGMPHDDPRMRRAVQWLVSIQNDDGGWGEGGESYKLDYRGYE
RAPSTASQTAWALLGLMAAGEVDHEAVARGIDYLQREQREHGLWDETRFTATGFPRVFYL
RYHGYRKFFPLWALARFRHLKRNGLTRVTVGM
>A0A7V2KQI0|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
MATLKDSRSQAIDLNKLDEAIRRAQGYILERQAAEGYWVAELEADASVTAGYIPVMRLFA
PIPAPRLRRIVDFLLSKQGPDGGWPLYYGSRGDLNVSIQVYFALKLAGVSPQEPFMKRAR
ELIRSQGGVNRANTFTKVFLAIFGQHDWRDTPSLPPEIMFLPRHFPFNIYDFASWARATI
VALTVVLAKKPVYPVPPSADIGELYVEPKGKLAYSLPQATRLFSWGRLFLWADSVLKLYE
RLPFKPGRALALRRAQEWILEHQEADGSWGGIMLPWVYSLVALKCLGFPPDHPALARGVA
GLESFVVEDETTFRLQPAVSVVWDTALSLIALLDSGLPPDHRSLVKAAQWLLGKQILVPG
DWQICNPKAQPGGWAYEFHNNFYPDLDDTPVVCQALSRISLPDEETKAQAISRGLGWALA
MQSRDGGWAAFDRDNDFQPIAQIPFAEFMPPLDPTCPDVTAHVVELLGHLGYNPDHPPLR
RAIAYLKRTQEADGAWYGRWGVNYIYGTGLVLPALRAAGEDMQAEYIQRAVGWLRSHQNP
DGGWGESCYTYEDPATRGQGASTASQTAWALMGLLAAGEAASPSVRKGVEYLLRTQQADG
SWVEEYFTGGGFPRAFYLRYHWYPKYFPLMALGRYRAMVRGSRETRA
>A0A418TB75|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus sp. 1011MAR3C5|TrEMBL
MRKKVDQGITQLVDWLVKEQKEDGSWRFCFENGIIIDAYALILFRLLEHENEELLRKLHN
RIAASQQPDGCWRLYPDEEEGSLSASIEAYYALLISGYSQADDEHMQRAKAYILSRGGIG
MVRSTLTKTILAATGQRDWPRSISTIPMEILLVPSELPLSLFSFSGYARVHLVPMLVMGS
RKFSLRTERTPDLSSLYANRDTGDEASLPSHMAMRVQIQTGMERLIGSPRSLRDAAADKA
EAFMLERIEGDGTLYSYATSTIMMIFALLALDYGKNHPVIQKACQGLADMRFDTEGITTI
QNSPSDIWDTALISYALQEAGVSHRHEAILNASAFLLSRQHTRKGDWSKNNPNTPPGGWG
FSETNTMNPDVDDTTAALRAIHRLAVDEPVYAEAWHRGLNWVTSMQNRDGGWPAFEKETN
NQMLTWLAIEGAKSAAIDPSEPDLTGRALEYLGKFAQLHTNERFVKRGVDWLLRNQERNG
SWYGRWGVCYLYGTWAALTGLAAAGVPSSHEAIKKGAEWLLRMQQSDGGWGESCRSDSKS
HYVSIGASTPSQTAWALDALIAVSSEATPAIKRGIKRLIGFLHENNWKTDYPTGAALPGY
FYVRYHSYRYIWPLAALAHYREKFG
>A0A6L3N1L7|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia stagnalis|TrEMBL
MNPIPVFSSAALDAAIVRGRDALAHLQQPDGSWCFELESDATITAEYILMMHFMDKIDEV
RQAQMARYLRAIQRLDSHGAWDLYVDGAPDISCSVKAYFALKAAGDSEHAPHMVRARETI
LKLGGAARSNVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTTMVPL
LVLCSLKARARNPRNVSIRELFVTPPDEERRYFPPATGMRKLFLAMDRVVRHVEPLLPKR
LRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMEVLGYPEDHPLRRDCENALEKLL
VTRADGSMYCQPCLSPVWDTAWSTMALEQARGATQDAQVPDRELDARIARAYDWLATRQV
NDLEGDWRENARRGTPPGGWAFQYANPHYPDIDDTAVVTAMLDRRGRAQARVSGKDPYAE
RVSRALDWMRGLQSRNGGFGAFDADCDRMYLNAIPFADHGALLDPPTEDVSGRVLLCFGV
TRREEDKAARARCIEYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALSGEDKSQPYIVR
ALDWLRAQQHADGGWGETNDSYADPRLGGTNYGESTSNYTAWALLAQMAFGDWQSDSVRR
GIAYLLSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLAGAQSAPPV
RDPGTANAIADQAVA
>A0A6G9F2T9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. VN1|TrEMBL
MTATTDGSTGASLRPLAASASDTDITIPDTAAGVPEAAARATQRATDFLLSRQDAQGWWK
GDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDAPDAPHMARASEWIRSRGGVASARVFTRIWLALFGWWKWDDLPELPPEII
YFPTWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPARPNPQRPLAPAA
SWDGAFQRIDRALHAYRKVAPRRLRKAAMNSAARWIVERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPSDHP
QLVRAADWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHH
DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVTAH
VVESLAVEGLAHDPRTRRGIQWLLDHQEADGSWFGRWGVNYVYGTGSVIPALTAAGLPAS
HPAIRRAVRWLESVQNEDGGWGEDLRSYRYVREWSGRGASTASQTGWALMALLAAGERES
RTVERGVEWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFA
KKSRAAEIRTGAAPAEVKGS
>A0A7Z6TF77|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. CBMAI 2042|TrEMBL
MTATTDGSTGAANLSAAPAGHPADTTTAADDVTAAARQAAERSVAHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPSDLSATIEAY
VALRLAGDRPDEPHMARASAWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPAEPNPPRKLAAAASW
DGLFQRLDKGLHLYHKVAPRLLRRIAMNVAARWIVERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMVEACQSPVWDTCLATIALVDGGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARLEAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLGSHPRTRRGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALVAAGLPAAHP
SIRRAVTWLESVQNDDGGWGEDLRSYTEEKWIGHGESTASQTAWALLALLAAGRRDSRAV
ARGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRT
GAAQGA
>A0A375E8M8|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus taiwanensis|TrEMBL
MSLNETAFANAAPQVDSAPRQPAGPAQAPATRLSAPALDHGIGRALDALLHQQRPDGHWI
YELEADATIPAEYVLMVHYLGEAPDLDMEARMARYLRRIQNPDGGWPLFHQGRSDVSASV
KAYFALKMAGDDPQSAPMQRARQAIHAMGGAEASNVFTRTLLALYGVLPWKAVPMMPVEI
MLLPRWFPFHLSKVSYWARTVIVPLLVLNSLRPQARNPRGVGINELFVGNCHTVGLPPRA
PHQHAGWYTVFRGLDALLRVAEPLFPRTLRRRAIAAAQRFVRERLNGEDGLGAIFPAMAN
SVMMFDVLGVPPDDPARAVARHSLERLLVEHGDEAYCQPCLSPVWDTALATHALLETGEA
RAAQAAKRALDWLRPLQVLDLRGDWAVRRPLVRPGGWAFQYANAYYPDVDDTAVVAAAMD
RFMRAHDAPGRYGEAVARATEWIVGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDPP
TADVSARCLSMLCQTGATPGKSEPAARALRYLLAEQMPDGSWFGRWGTNYIYGTWSALCA
LNAAGLPPAAPELQRAVAWLARIQNADGGWGEDGSSYRLDYRGYEPAPSVASQTAWALLA
MMAAGAAQHPAVARGIDYLLRTQQPGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWALA
RYRNLQRGPMGQMGQSGQVSWGL
>A0A6N2DCU0|squalene-hopene cyclase|EC 5.4.99.17|Phormidium sp. GEM2.Bin31|TrEMBL
MDRNRLQQAIQASQEYLLQQQHPDGYWWADLESNVTMLAEVILLHKIWQLEDRLPWEKAE
RFFREQQQNHGGWELFRGDGGDLSTSVEAYLGLRLLGVPATDPALVNAKTFILAKGGIGK
TRVFTKMHLALIGAYDWRGVPSIPPWIMLLPGEAPFSIYDMSSWARGSTVPLLIVFDEKP
VYRLDPHISLDELYTEGMAAASFELPRTGDWSDAFVELDNLFKWGEQLNLVPFREEGLRA
AEQWVIERQEASGDWGGIIPAMLNSMLALRSLNYDLADPVVERGFEAIARFGVETDNTYW
VQPCVSPVWDTAWVVRSLIESGIAPDDPRIVKGGNWLLSQQILDYGDWQVKNQTGEPGGW
AFEFDNRFYPDLDDSAVVIMALNQTQLPHPEKTQAAVKRGIRWILSMQCQNGGWAAFDVD
NDKDWLNALPYSDLKATIDPPTADVTARILEMAGELETDAQETPLQENSEQFEQALAYLL
GEQEEDGSWFGRWGVNYIYGTSGALSALALVTPERHRGPLERGANWLLSVQNADGGWGET
CLSYDHPRFKGDGDSTASQTAWALLGLMAVAKVLDSGSGPAWREAIARGVDYLMETQQPD
GTWDESWFTGTGFPSHFYLRYDYYRLYFPLLALGRYRQMS
>A0A5N5EKB7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces arboris|TrEMBL
MTATTDGSTGAANLSAPPAGHPADTTTAADDVLAAARRAAERSVAHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYEGPSDLSATIEAY
VALRLAGDRPDEPHMARASAWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPAEPNPPRKLAPAASW
DGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIVERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMVEACQSPVWDTCLATIALVDGGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
VRLEAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLGAHPRTRRGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALVAAGLPAAHP
SIRRAVTWLESVQNDDGGWGEDLRSYTEEKWIGHGESTASQTAWALLALLAAGRRDSRAV
ARGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRT
GAAKGA
>A0A4D8PHD6|squalene-hopene cyclase|EC 5.4.99.17|Azospirillum brasilense|TrEMBL
MQDHNASTTLRVQRAEPSAKAVSDAVAEATDALIRRQQADGHWVFELEADATIPSEYLLL
HHILDEIDPELEAGLAAFIRGRQGRDGGWPLFFGGAMDISCSVKAYFALKAAGDSPDAPH
MRRAREAILARGGAARCNVFTRILLAQFGQIPWRAVPAMPVEVMNLPPWSPFHISRISYW
SRTVVVPLLVVMAHRLRARNPRGIGIAELFTEPPERVRNWHSNNSRGGWATLFRALDAAL
HAVEPRLPANGRQTAIDRAVRFVTERLNGEDGLGAIFPAMVNAVLMFHCLGMPPDHPDAA
MARRALHGLVVRQPGRVYCQPCLSPVWDTAIICNALLETGSPLARAAARRGADWLIDRQI
LDVEGDWAWQRPGLASGGWAFQYNNAHYPDTDDTAMVVMALQRLDADRYGEPIRRARDWI
VGMQSRNGGWGAFDAENQHDFLNHIPFADHGALLDPPTSDVTARCVMMLARLGEGRDTVP
TRRGLTFLEREQESDGAWFGRWGTNYVYGTWSALEALNAAGVPHSAVAVQRAAQWLLAHQ
RADGGWGEDGASYWAGNPRGEGPVSTASQTAWALLGLMAAGKGNHPAVDRGVEYLLSARD
AEGLWSEEPFTAVGFPRVFYLKYHGYAASFPLWALARYRALRA
>A0A538QLE3|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Rokubacteria bacterium|TrEMBL
MHGQVVPGRVCMLPSAFVTALRDAISRAQHHLLSVQAPDGHWIGELEADRALTAEYLLLC
HLIDHVNREQERRAVRFLRRRQNADGGWSLFEAGSSDLSATIKVYFAMKMAGVGVDDPVM
VAARERIRAMGGPTKSSAFTKILLALFGEYDWNGVPTMPAEIMLLPPPFFLFNIYEVSYW
SRTVIVPLLIIMDRKPIKWLPPGQSLDELWPVPREQASLRFPRVPEPFSWRGLFWKSFFI
AVDDGLKIWERFSPRPLRKRAIEAARQWLEERLSVPGGLGGIYPAMANSVLALRLLGYPD
DHPLILGQLKEIEALAVEHGDELSYQPCPSPVCDTSLAVNALVESGVPSDHPALVRAVDW
MLAKQVALPGDWQVKRPHVQPGGWAFQYDNPFYPDLDDTAMVLMALEKVHGVDPDRLRQA
KERGLGWFLGMQNQDGGWASFDADNNRLFLNNIPFADHGALLDPSTEDLTGRGLELLGTL
GYDLEFEPADRALDFIRHSQRHDGPWYGRWGVNYIYGTWSVLRGLGAMGVDPRHEYVQRA
ARWLVRRQNADGGWGETCESYVKAELAGRGPSIPSQTAWALLALFAVGTTTGPAVEAGIE
YLLRTQRADGGWEDPFWNGTGFPRVFYLKYHLYAAYFPLWALGVYRKLRMHD
>A0A6B3DMJ5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8499|TrEMBL
MTATTDGSTGATLPTRAAAASEPVLTTPVAAGVHQAAEHAVRRATDFLLSRQDAEGWWKG
DLETNVTMDAEDLLLRQFLGIQDEATTHAAALFIRGEQREDGTWATFYGGPGELSTTIEA
YVALRLAGDAPDAPHMAKAAAWVRARGGIAASRVFTRIWLALFGWWKWEDLPELPPELIY
FPTWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAQPNPVKPLAPAAS
WDGAFQRLDKALHAFRKVAPKRLRRSAMNTAARWIIERQENDGCWGGIQPPAVYSIIALH
LLGYDLQHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQ
LVKAADWMLGEEIVRPGDWSVRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHD
PERVDRAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGLAHDPRTRRGIQWLLEEQEPDGSWFGRWGVNYIYGTGSVVPALTAAGLPGSH
PAIRRAVAWLKRVQNDDGGWGEDLRSYRDSKKWSGKGASTASQTAWALMALLAAGERDSE
AVERGVRWLADTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFAA
QAPAGRPLAEAKGS
>A0A6L3T3N8|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium soli|TrEMBL
MREAVNKVEALQRPKTQDISLEDVERGVVSATRALTRLAHADGHICFELEADATIPSEYI
LFHQFRATTPRPGLEEKIAQYLRRTQGKHGGWALVHEGPFDISASVKAYFALKMIGDDIE
APHMRRAREAILSRGGAANSNVFTRFLLALYGEVPWRAVPVMPVEVMFLPKWFPFHLDKV
SYWARCVMVPMFVLQATKPRARNPRGIGVQELFVTPPDHVRTWPGSPHATWPWTPIFGGI
DRVLQKVENFLPKTPRRRAKEKAVAWVSERLNGEDGLGAIFPAMVNTVLMYEVMGYPSDH
PQVRIACEAIEKLVVEKDHEAYVQPCVSPVWDTALASHALLEAGGPDAEQQARRGLDWLK
PRQVLDIVGDWAASRPNVRPGGWAFQYANAHYPDLDDTAVVVMAMHRAMRQHGLVADMPD
YTTAIARAREWVEGLQSSDGGWAAFDADNNHMYLNHIPFSDHGALLDPPTADVTARVVSM
LAQLGETRASSKALDRGVDYLFAEQEKDGSWYGRWGMNFIYGTWSVLCALNAAGVDPQSP
EVRRAVAWLIRIQNPDGGWGEDASSYKIDPAFEPGYSTASQTAWALLALMAAGAADEAAV
TRGINYLARTQGADGFWNEERYTATGFPRVFYLRYHGYSKFFPLWAMARYRNLKHSNTRQ
VAFGM
>A0A6I2SLK9|squalene-hopene cyclase|EC 5.4.99.17|Geobacter sp|TrEMBL
MTPCKHPISHALTSFNGVTAEPEIKPTAKPGAKIHHLPASIWKKKENETTSPLDLAIERT
CEFFFREQLPQGYWWAELESNVTITAEYVMLFHFMGIVDKAKERKMANYLLRQQTEEGHW
SLWYGGPGDLSTTIEAYFALKLAGYPADHPSMVKARDFILSQGGILKARVFTKIFLALFG
EFSWLGVPSMPIELMLLPNWAYFNMYELSSWSRATIIPLSITMTMRPVRKLPPWARVQEL
YVRPPRPMDYTFTKENGIFTWKNFFIGLDHLLKVYEGNPIRPLKNKGMAAAEKWVLEHQE
PTGDWGGIQPAMLNSVLSLHCLGYANDHPAVAKGLQALANFCIEDDESLVLQSCVSPLWD
TALALKALVEAGVPTDHPALVKAAQWLLDREVRKDGDWKIKSPNLKPGGWAFEFLNDWYP
DVDDSGFVMMAIKDVQVKNEKTKQEAIQRGIDWCLGMQSKNGGWGAFDKDNTKHLLNKIP
FADLEALIDPPTADLTGRMMELMGTFGYSKEDPVAVRALDFLRREQEPDGSWWGRWGVNY
IYGTWSVLSGLSAMGENPNQAYIRRAIDWMKSKQNADGGWGETCESYLDPSLAGIGPSTA
SQTGWALLALMTVGEVDAPEVSRGIQYLLDTQKADGTWDEDQYTGTGFPKFFMIKYHIYR
NCFPLTALGTYRSLSRKRKG
>Q0BQ97|squalene-hopene cyclase|EC 5.4.99.17|Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)|TrEMBL
MPKDIPADLASEAISGDMLEQAVLRASMALHRKQQTDGHWVFELEADATIPAEYVLLEHF
LDRIDDDLERKIGVYLRRIQGDHGGWPLFHEGAFNLSASVKAYYALKAIGDDPDAPHMRR
AREAILAAGGAERSNVFTRIQLALFGQIPWRGVPVMPAELMIAPKWFPINMWKVSYWSRT
VIAPLLVLMDRKPKARNPRNVHVRELFLHDPDRIRDWIRGPFRSGWGHFFKYLDSVLRVV
EPVALKPMRPRSIRLAVDFVRERLNGEDGLGAIYPAMANSVMMYDVLGYSPDHPEAAIAW
ESVRKLLVIKEDEAYCQPCLSPIWDTGLSGHAMAEAEGAVSPGVAAACDWLRNRQITDVV
GDWAEIRPGVQPGGWAFQYNNAHYPDVDDTAVVAMLLHRQGDPAHEESIRKAREWIIGLQ
CRDGGWGAFDADNDKDYLNHIPFADHGALLDPPTADVTARCISFLAQLGNPEDKPVIDRA
MAWLRKEQEADGSWFGRWGTNYIYGTWSVLCAMNVAGMPHDDPAIRRAVNFLVATQREDG
GWGEDEETYDPASGAQPGRYKESTPSQTAWALIGLMAAGEAEHEATRRGIAYLQATQKPD
GEWDEAAYTAVGFPRVFYLKYHGYRQFFPLMALSRYKNLRSSNMKKVSFGF
>A0A0H3KQ38|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia multivorans (strain ATCC 17616 / 249)|TrEMBL
MNDLTDMATLSAGTVPAELDAAVARATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRAVDHVLR
AVDGLFPAYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKSIEKLLVVHEDEAYCQPCLSPVWDTSLAAHALLETRDPRAEQAAVRGLDWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANPHYPDVDDTAVVAMAMDRAQKLNQSDTYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETAL
NSDAARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCALNAAGLGPDDARVKRAAQWL
LSIQNKDGGWGEDGDSYKLNYRGYEPAPSTASQTAWALLGLMAAGEVNNPAVKRGIDYLI
AEQKEHGLWDEARFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNTTRVTVGI
>A0A4V3Z1C1|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. LS-044|TrEMBL
MIRRMTRSTPSPWSALDTAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDLRQERMARYLRANQRLDTHGGWALYVDGDPDVSCSVKAYFALKAAGDSEHAPHMVRA
RDAILKLGGAARSNVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNVSIRELFVTPPDEERRYFPPARGMRKLFLALDRTVRHVEPL
MPKGLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMQVLGYPDDHPLRRDCENAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVAVPEDGEPDDARRALDARIARAY
DWLAERQVNDLRGDWIENAPADVQPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRTHRNA
DGTNPYAPRVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRADERASLARCIEYVKRTQQPDGSWWGRWGTNYIYGTWSVLAGLALAGED
KSQPYIARAIEWLRSRQHADGGWGETNDSYIDPKLGGTNGGESTSNFTAWALLAQMAFGD
CESDSVKRGIAYLQSVQQEDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GAAAAAPAAVDAADTAVA
>A0A3N8KWE2|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp8963|TrEMBL
MNDLTDMPTLTADTQSAGLDAAVARATDALLAAQNADGHWVYELEADSTIPAEYILLVHY
LGETPNLELEQKIGRYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARKAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPIAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANSVMMYAALGYPEDHPNRAI
ARQSVEKLLVVHGDEAYCQPCLSPVWDTSLAAHALLETGDPRAEDAVVRGLEWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANPHYPDVDDTAVVVMAMDRVEKLRHSDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETAA
NSEAARRSLDYMLKEQEPDGSWYGRWGMNFVYGTWTALCSLNAAGLGPDDPRVKRGAQWL
LSVQNKDGGWGEDGDSYKLNYRGYEQAPSTASQTAWALLGLMAAGEVNHPAVARGIDYLI
AEQNEHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNATRVTVGM
>A0A6G4V804|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces scabichelini|TrEMBL
MTATTDGSTGALPPRAASASETITKTPVAAGRTDVQDAARHAIQRATDFLLATQDAQGWW
KGDLETNVTMDAEDLLLRQFLGIRDEKTTHAAGLFIRGEQGEDGTWATFYGGPGELSTTI
EAYVALRLAGDSPDAPHMAKASAWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPPEL
IYFPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDASNPNPVKPLAPV
GSWNGVFQRLDKALHVYHKVAPRRLRRTAMNTAARWIIERQENDGCWGGIQPPAVYSIIA
LHLLGYDLEHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADH
PQLVKAADWMLGEEIVRPGDWAVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKH
HDPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVTA
HVVEMLAVEGLSHDPRTRRGIEWLLAAQETDGSWFGRWGVNYVYGTGSVVPALVAAGLPG
AHPAIRRAVAWLETVQNDDGGWGEDLRSYRDVAEWSGRGASTASQTGWALLALLAAGERE
SKAVERGITWLAQTQREDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPF
TDRQAKGS
>A0A5J6IVY3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces cinereoruber|TrEMBL
MTATTDGSAGAVSPRTAVDGETTDTALPERAAPAPGRLDETAARAAARAAEHLLARQDPA
GWWKGDLETNVTMDAEDLLLRQFLGILDPDTARAAALHVRREQREDGTWSTFYGGPGELS
TTVEAYVALRLAGDPPDAPHMARASAWVRAHGGIADTRVFTRIWLALFGWWRWEDLPELP
PEMLFLPKWFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPARPNPPRPL
APATGWDGIFQRIDKALHLYHRVAPRPVREVAVNLAAQWIVERQENDGCWGGIQPPAVYS
IIALHLLGYDLGHPVMRAGLESLDRFALWREDGSRMIEACQSPVWDTCLATIALADAGLP
PDHPALVKAVDWMLDEEITRTGDWAVRRPGLPPGGWAFEFHNDNYPDTDDTAEVLLALRR
VRHPDPARVEAAAARGTRWTLGMQSRDGAWGAFDADNTSVLPNKLPFCDFGEVVDPPSAD
VTAHVVEMLAHEGLAGDPRTLRGIDWLLAAQEPDGGWFGRWGVNLVYGTGSVLPALAAAG
IPASHPAVRRAVAWLGSVQNEDGGWGEDLRSYQDEQWVGRGASTASQTAWALIALLAAGE
RESEPVRRGVAWLTATQLPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYAHGE
PSLRKEG
>A0A1Y0XXR0|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter pasteurianus subsp. pasteurianus|TrEMBL
MAADGSALSESRLSSEALDRAVLSAHTALSQAQQDDGHWVYELEADATIPAEYILLEHFM
DRIDDALEQKIAIYLRRIQSEEHGGWPLYHNGKFDLSATVKAYFALKAVGDDINAPHMQR
AREAILDHGGAERSNVFTRSQLALFGEVPWRATPVMPVELMLLPAKAFFSVWNMSYWSRT
VIAPLLVLAALRPVAANPRQVHVRELFVTPPEKVQDWIRGPYRSAWGYVFKGLDSVLRPV
VPFIPEKTHKKAIQAALDFIEPRLNGKDGLGAIYPAMANVVMMYRAMGVPDEDPRAKTAW
EAVQALIVEKDDEAYCQPCVSPIWDTGLSGHAMIEAASGPNGIAPEKTLSKLKTACAWLR
SKQILNVKGDWAVRNPNLAPGGWAFQYGNDYYPDVDDTAVVGMLLHREGDPANAESIERA
RTWIVGMQSTDGGWGAFDIDNNKDVLNHIPFADHGALLDPPTADVTARCISFLAQLRNPE
DEPVIQRGLEYLRKEQEKDGSWFGRWGTNYIYGTWSALCALNAAGVSHDDPAVVKAVEWL
RSVQRADGGWGEGCESYEGGPHGTYGESLPSQTAWAVLGLMAAGRRDDPAVARGISWLAD
QQDANGEWHEDPYNAVGFPKVFYLRYHGYKQFFPLMALARYRNLENSNSRRVSFGF
>A0A537L7P8|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MDDRTTLPPAAALNKLDPALERQIRAATDALLADQQPDGHWVFELEADATIPAEYVLMVH
YFAEEPNLELERKIGVYLRRIQGAHGGWPLFHEGAFDMSASVKAYFALKMIGDDVNAPHM
KRAREAILSRGGGIKSNVFTRALLSLYGVLAWKSVPVMPVEIMLLPKWFPFHIDKISYWA
RTVIVPLLVLQALKPKAINPRGVTIDELFHEDPKTIGPPHKAPHQKWSWFITFRAIDIVL
RALAPYLPKGPRKRAIDKAVAFVTERLNGIDGLGAIYPAMENSVKMYAVLGYAPDHPHRA
IARASLDKLLVIKDDEAYCQPCVSPVWDTALVAHALLEAGDEKAVAAANRGLDWLKPLQV
LDVKGDWIEQRPDVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRVRGARGTTFDQAIERGR
EWVVGLQSKDGGWGAFDADNAYHYLNNIPFADHGALLDPPTADLTARCLSMLAQLGERPE
TSEPMRRALRWLERDQLPDGSWYGRWGMNYIYGTWSVLCALNAAGVDPQLPMFRKAVQWL
LAIQNEDGGWGEDGTSYKLDYRGHEKAPSTASQTAWALLGLMAAREIEHAAVRRGIAYLA
ENQGNDGLWEEQRYTATGFPRVFYLRYHGYRRFFPLWAMARYRNLKSGNSRAVSFGM
>A0A0B6S5P8|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia plantarii|TrEMBL
MSPADTTPTPGAAPTPSIPAPTDASTLAPADLDAAVTRATDALLAAQQPDGHWVYELEAD
STIPAEYVLLVHYLGETPNLELERKIARYLRRVQLPGGGWPLFTDGAPDVSASVKAYFAL
KMIGDDADAEHMVRARNAIHAMGGAEMSNVFTRIQLALFGVVPWFAVPMMPVEIMLLPQW
FPFHLSKVSYWARTVTVPLLVLNAKRPLAKNPRGVRVDELFVAPPVNAGLLPRAGHQSPA
WFACFRVLDGLLRLTDGLFPRYTRERAIRQAVQFVDERLNGEDGLGAIYPAMANSVMMYA
ALGYPEDHPNRAIARRSLEKLLVIHDDETDEAYCQPCLSPVWDTSLAAHALLETGEPRAE
AAAIRGLDWLRPLQILDVRGDWISRRPDVRPGGWAFQYANPHYPDVDDTAVVALAMDRVA
KLANTDVYRDAIARAREWVVGMQSSDGGWGAFEPENTHHYLNSIPFSDHGALLDPPTADV
SGRCLSMLAQLGETTGNSPPARFALDYLLAEQEPDGSWYGRWGMNYIYGTWSALGALNAA
GLPFDDPRVKRAAQWLLSIQNPDGGWGEDGNSYKLDYRGYERATSTASQTAWALLGLMAA
GEIEHPAVARGIAWLAAEQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRN
LRRSGTRRVTVGM
>A0A5D4UNL6|squalene-hopene cyclase|EC 5.4.99.17|Rossellomorea aquimaris|TrEMBL
MKKKIENTIHKKVNDLQHRQNAEGSWSFCFENSVMTDAYMIILLRSLEVDEEELVGRLVN
RLWKVQSREGTWKLFDDEKEGNLSSTIEAYFALLFSGLVEKEDKRLEKAQRFIEKKGGIH
GAHSITKFMLAIHGQYDWRHLLPVPIEFLMIPKQFPLNFWDFSSYARAHLAPLLLLKDQG
FSLKSNSIPQIQHLSRTPHEVRYSARELKLFSKINEGLQSLISIPTLLHQQARQFAQQYM
LQRIEPDGTYLSYFSTTFYMIYSLLALGYKKSDPIIVKAMSGLKEMASETKKGIHIQNSP
STVWDTALISYSLQEAGVDAREHSIEKAVEYLLKKQHFRYGDWAMESRAKPGGWGFSKSN
SIHPDVDDTTAALRAITYSAAEKPLVRQSWDRGIEWTLGMQNREGGWPAFEKNKTKGILT
SFPMDGAEAAAIDPSTPDLTGRALEFLGNRAGLTMDHPQVKRGVQWLKLMQKDDGSWYGR
WGVCYIYGTWAAITGMKATGVPSSDKHIQKAKAWLESIQHKDGGWGESCYSDQEKTYVPL
SYSTPSQTAWALESLICIEDKPTPAIDLGIMALLEFMNGEADDSSKTYPTGVGLPGNFYI
HYHSYQWIWPLITLSRYKEKYS
>A0A5C8U0E8|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium sp. WL9|TrEMBL
MREAAAHKPDSKVESLQRAKTRDISLDSVERGIHAATRALSDLVQPDGHICFELEADATI
PSEYILFHQFRATNPRPGLEQKIGNYLRRTQSGKHHGWSLVHDGAFDMSCTVKAYFALKM
IGDDIEAPHMRKARAAILSRGGARNANVFTRFMLALYGEVPWRAVPAMPVEVMHLPTWFP
FHLDKVSYWARCTMVPLFVLQAKKPLAKNPRGIRIQELFTTPPDSVRSWPGSPHATWPWT
PIFGGIDRVLQKTERYFPKTPRRRAIDKAVAWVSERLNGEDGLGAIFPAMVNSVLMYDVL
GYATDHPQVRIACEAIEKLVAEKEHEAYVQPCLSPVWDTALSAHALLEAGGGQAEGAARD
GLDWLTPLQVLDIKGDWAATKPDVRPGGWAFQYANPHYPDLDDTAVVVMAMDRAMRQHGL
VSDMPDYSTPIARAREWVEGLQSADGGWAAFDADNNHHYLNHIPFSDHGALLDPPTADVT
ARVVSMLSQLGETRQSSRALDRGVTYLLNDQETDGSWYGRWGMNFIYGTWSVLCALNAAG
VEGSHPQIRRSVEWLIRIQNPDGGWGEDASSYKVDPEFEAGYSTASQTAWALLALMAAGE
VDDPAVARGVNFLTRTQGADGFWSEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLK
LGNSRQVAYGM
>A0A7H8M840|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. NAK00032|TrEMBL
MTTLETPQTPAAAATRTAAEALDAARDHLLLLQSPQGWWKGELQTNVTMDAEDLLLREFL
GIRTDEDTCEAARWIRSQQAPDGTWANFHDGPPDLSTTVEAYVALRLAGDLPDAGHMVRA
AAYIRSGGGVPATRVFTRFWLAMFGRWPWDELPVVPPEMMFLPRWFPLNVYDFACWARQT
IVPLTVVGALRPVRPLPFGLDELVPDYDVPRRRRRGLPGWGEAFGALDRALHVYQRHAPR
RRPLKGVREAALRRAGEWIIARQERDGSWGGIQPPWVYSLIALHLLGYGLDHPVVQRGLD
GLERFTIRDERGRRLEACQSPVWDTVLAMNALADAGLPAGHPALERAAEWVLGEEVRGPG
DWSVRRPGLPPGGWAFEFDNDVYPDVDDTAEAVIALDRVRHPRAEPAIERGVRWMAGMVS
RDGGFAAFDADNTRALCRRLPFCDFGEVIDPPSADVTAHVVEALAHRGMADSLLAKRAVV
WLLKAQEPDGSWFGRWGANHVYGTGAVVPALIAAGVRPQKPAVRDAVGWLERHQRDDGGW
GEDLRSYRDRSWAGHGVSTASQTAWALLALLAAGERGPAVERGIRWLAEHQRPDGTWDED
HFTGTGFPGDFYINYHLYRLVFPLSALGRYLGAGAAAPGGPGGGSKEAF
>A0A365R3J7|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia reimsis|TrEMBL
MNDLTEMATLSAGTVPAGVDAAVARATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNVELEQKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AADGLFPNYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKSIEKLLVVHDDEAYCQPCLSPVWDTSLAAHALLETGDARAEEAVLRGLEWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAVAMDRAQKLRQNDAYRDSIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLI
ANQNEEGLWDEARFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNTTRVTFGL
>A0A858Q674|squalene-hopene cyclase|EC 5.4.99.17|Methylococcus geothermalis|TrEMBL
MLREATVISNLEPPLTASYVESPLDAAIRRAKDHLLSLQHQEGYWVFELEADCTIPAEYI
LMMHFMDEIDEKLQARIANYLRAHQSADGSYPLFQGGAGDISCTVKVYYALKLAGDPIDA
PHMTKAREWILAQGGAARSNVFTRIMLAMFEQIPWRGIPFIPVEIMLLPKWFPFHLDKVS
YWSRTVMVPLFILCSHKVTARNPTKTQIRELFTVDPQRERHYFDHVRTPLGKAILGLERF
GRMLEPLIPSAVRKKATQKAFEWFTVRLNGVDGLGAIFPAMVNAYEALDFLGVPPDDERR
RIARESIERLLVFQGESAYCQPCVSPIWDTALTALTLQEVARHTADLQLDAALHKGLQWL
ASKQIDKDAPGDWRVNRPNLEGGGWAFQFGNDYYPDVDDSAVVAHALQGSGDPRFDETLR
LAANWIAGMQSSNGGFGAFDADNTYYYLNSIPFADHGALLDPPTADVSARCAMFLAKRVD
RQPELRPALDRTIAYLRREQEADGSWFGRWGTNYIYGTWSVLLAYEAAGIPNDDPSVRRA
VAWLKSVQREDGGWGEDNFSYHDTSYRGSFHTSTAFQTGFALIALIAAGEALSPEVQAGV
DYLLRQQRADGFWNDECFTAPGFPRVFYLKYHGYDKFFPLWALARYRNERYARA
>B0U917|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium sp. (strain 4-46)|TrEMBL
MGKVETLHRTSTQDITLDDVERRVTLASKALMRLANADGHWCFELEADATIPSEYILYHH
FRGSIPTAELEGKIAAYLRRTQSAQHDGWALIHDGPFDMSATVKAYFALKMVGDPIDAPH
MRRARDAILRRGGAAHANVFTRIMLALYGEVPWTAVPVMPVEVMLLPRWFPFHLDKVSYW
ARTVMVPLFVLQAKKPRARNPRGIGIRELFVEAPERVKRWPAGPQESSPWRPVFAAIDKV
LQKVEGFFPAGSRARAIDKAVAFVSERLNGEDGLGAIFPAMVNTVLMFEALGYPDDHPFA
VTARSSVEKLVTVKEHEAYVQPCLSPVWDTALAAHALMEAGGTEAERHAKRAMDWLKPLQ
VLDIKGDWAASKPDVRPGGWAFQYANPHYPDLDDTAVVVMAMDRVQSRRSPGPDAADYGL
SIARAREWVEGLQSRDGGWAAFDADNTYHYLNYIPFSDHGALLDPPTADVTARCVSMLSQ
LGETRETCPPLDRGVAYLLADQEADGSWYGRWGMNYIYGTWSVLCALNAAGIDPACEPVR
RAVTWLTAIQNPDGGWGEDASSYKLEYRGYERAPSTASQTAWALLALMAAGEADNPAVAR
GINYLTRTQGADGLWAEDRYTATGFPRVFYLRYHGYAKFFPLWALARYRNLQRGNSLKVA
VGM
>A0A7M2T686|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces chromofuscus|TrEMBL
MTATTDGSTGALPPRAAAASETDSTTPVAAGVHEAAVHAVRRATDFLLSRQDAEGWWKGD
LETNVTMDAEDLLLRQFLGIREESTTLAAALFIRGEQREDGTWATFHGGPGELSTTIEAY
VALRLAGDAPDAPHMAKAAEWIRAQGGIAASRVFTRIWLALFGWWKWEDLPELPPELIYF
PKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPDHPNPVKPLAPAATW
DGAFQRLDKGLHALRKVVPRKLRRAAMRSAARWIIERQENDGCWGGIQPPAVYSLIALHL
LGYDLRHPVMRAGLESLDRYAVQRGDGARMIEACQSPVWDTCLATVALVDAGVPADHPQL
VKAADWMLGEQVVRPGDWSVRRPGLTPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHHDP
ERVEKAIARGVRWNLGMQSKDGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIEWLLAEQEPNGSWFGRWGVNYIYGTGSVVPALTTAGLPASHP
AIRRAVAWLESVQNDDGGWGEDLRSYRHVKEWSGRGASTASQTAWALMALLAAGERDSKA
VERGIEWLAATQREDGSWDEVYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFAPT
SLAEAKVAG
>A0A7G8KK84|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces buecherae|TrEMBL
MTATVVETTTVLTAARQATARAVDHLLARQDKEGWWKGDLETNVTMDAEDLLLRQFLAIQ
DPGTTAAAARHIRSQQRPDGTWATFHGGPPDLSATIEAYVALRLAGDEPDAPYLAAAAAW
VREAGGIAASRVFTRIWLALFGWWSWDDLPELPPELIYLPKWAPLNIYDFGCWARQTIVP
LTIVSAKRPVRPAPFALDELHTDPRRPNPPRPLAPATTWDGAFQRLDRALHSYRKVAVRP
LRRAAIRSCARWIIERQENDGCWGGIQPPAVYSVIALHLLGYDLEHPVLRAGLASLDRFA
VWREDENGERVRMVEACQSPVWDTCLATIALADAGLPDDHPALVRAADWMLDEQVYKPGD
WSVRRPELRPGGWAFEFHNDNYPDIDDTAEVVLALRRVSHPDPQRVERAIQRGAEWNLGM
QSSNGAWGAFDADNVSPFPNKLPFCDFGEVIDPPSADVTAHVVEMLVALGERGDPRTQRG
IDWLLAEQEPNGAWFGRWGTNYLYGTGSVVPALVLAGIPTTHASIRRAVSWLESVQNEDG
GWGEDQRSYRERAWVGRGESTASQTAWALLALLAAGERESECVRRGIAWLAETQRPDGSW
DEPYFTGTGFPWDFSINYHLYRVVFPITALGRYIHAQPFGAERQGT
>F0IZ66|squalene-hopene cyclase|EC 5.4.99.17|Acidiphilium multivorum (strain DSM 11245 / JCM 8867 / NBRC 100883 / AIU 301)|TrEMBL
MFDTISFDFDALDQAISRAHARLSAEQRADGHYVYELEADATIPAEYVLLEHFLDRIDPE
LEARIGVFLRGIQGNSPQNPGGWPLFHDGAMDISASVKAYFALKAIGDDPDAPHMRRARE
AILARGGAARTNVFTRIQLALFGAVPWRACPVMPVEIMLLPDWFPITIWKISYWSRTVIA
PLLVLLTERPIARNPRNVRIDELFVTPPDQVTDYIRGPYRSNWGYLFKAIDSALRPLERH
FPARSRKRAIQAAIDFITPRLNGEDGLGAIYPAMANTVMMYHTLGYSPDHPDYATAWASV
RKLVTDASYRFEGASYVQPCLSPVWDTSLAAHALAEAGSPGDAQLAAACDWLIPRQILDV
KGDWAYRKPDAPPGGWAFQYNNAHYPDVDDTAVVGMILDRNGDPAHREAVERARQWILGM
QSRSGGWGAFDSDNEFHYLNHIPFADHGALLDPPTADVTARCISFLAQLGHAEDRPAIER
GVAYLRREQEQDGSWFGRWGTNYIYGTWSSLCALNAAGVAQDDPMMVRAVEWLLARQRPD
GGWGEDCETYAHAKPGEYHESLPSQTAWALLGLMAAGQAEHEAVARGIAWLQSVQEDDGS
WTEQPYNAVGFPRVFYLRYHGYPRFFPLLAMARYRNLARGNSRQVQFGF
>A0A3A2J284|squalene-hopene cyclase|EC 5.4.99.17|Methylococcales bacterium|TrEMBL
MFTDANTRTSTDNTSSSSTAIYSKSYDINKAISRAQESLLSKQDKDGYWVFELEADCTIP
SEYILMMHYLGEIDEQLQAKIANYLRPRQSEDGSYPLFTGGPGDISCCVKVYYALKLAGD
LPEAKHMTLLRNYILSRGGAAKANVFTRIELAKFKQLPWRGVPYIPVEIMLFPSWFPFHL
DKVAYWSRTVMVPLFILCTLKATAKNPTNISILELFVSHPDEEQHYFPERTLLNKIFLGL
DYLGRTTRPLIPKKAHDLAITKAKEWIIERLNGEDGLGGICPAMMGAYEALLLLETPEDK
DHIATARKALEKLLVINEHDAYCQPCLSPVWDTALAVLALQEADKNQSPITQSALTRAYD
WLKSKQLSDEPGDWRISKPNLEGGGWAFQFENPHYPDVDDTAVVAFAMADSNLPNLDESI
HRASRWIVGMQSKNGGYGAFDVDNTHYYLDEIPFADHGALLDPPTSDVSARCAMLMAKVA
QNHDEYRPALERTIQYLRDEQEVNGSWFGRWGTNYIYGTWSTLLGLEQTDLPKNDPMYIK
AVNWLKSMQREDGGWGEDNYSYHDKKLSGSYHFSTAFQTSWAL
>Q1QJY6|squalene-hopene cyclase|EC 5.4.99.17|Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14)|TrEMBL
MNSVNATVAPIDDAALGGSIGAATRGLLDLKQPDGHFVFELEADATIPSEYVLLRHYLGE
PVDAALEAKIAVYLRRIQGAHGGWPLVHDGPFDMSASVKAYFALKMIGDSIDAPHMARAR
EAILSRGGAANVNVFTRFLLSLFEVLTWRSAPVLPIEIMLLPMWSPFHINKISYWARTTM
VPLMVLAALKPRARNPRGIGIRELFLQDPATVGTPKRAPHQSPAWFTLFNSLDWILRKIE
PLFPKRLRARAIEKAIAFVEERLNGEDGLGAIFPPMVNTVMMYDALGFPPEHPPRAVARR
GIDKLLVIGKDEAYCQPCVSPIWDTALTCHALLEAGGPEALSGAGKSLDWLLPKQELVLK
GDWAVKRPDVRPGGWAFQYANAHYPDLDDTAVVVMAMDRVRRNDRSDKYNEAIARGREWI
EGMQSRDGGFAAFDADNLEYYLNNIPFSDHAALLDPPTEDVTARCVSMLAQLGETVRSSP
SMAAGVDYLRRTQLKEGSWYGRWGLNYIYGTWSVVCALNAAGVDHQDPAMRKAVDWLVSI
QNADGGWGEDAVSYRLDYKGFEGAPTTASQTAWALLALMAAGEVENPAVARGMKYLIDTQ
TKKGLWDEQRFTATGFPRVFYLRYHGYSRFFPLWALARYRNLRSTNSKVVGVGM
>A0A7X9X4S5|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia antibiotica|TrEMBL
MNDLSENQPLDAVLPEAADAALESASAPAATATLADAPAAAAADVPAAATSLDAAITRAT
DAILAAQQPDGHWVYELEADATIPAEYVLLVHYLGETPNLELEQKVARYLRRIQLPNGGW
PLFTDGALDISASVKAYFALKMIGDPADAEHMVRAREAILAHGGAENVNVFTRILLALFG
VVSWRAVPMMPVEIMLLPMWFPFHLSKVSYWARTVIVPLLVLNAKRPLARNPRKVRIDEL
FRGAPVNTGMNARAPHQHAGWFGFFRGVDAVLRTVDGLFPQATRERAIRAAVAFVDERLN
GEDGLGAIFPAMANSVMMYDVLGYPADHPNRAIARKSLDKLLVIKDDEAYCQPCLSPVWD
TSLAAHALLETGEARAEQAAERGLQWLLPLQILDVRGDWISRRPNVRPGGWAFQYNNAHY
PDVDDTAVVAMAMQRSAALTQSSAYRESIARAREWVVGMQSSDGGWGAFEPENTQYYLNN
IPFSDHGALLDPPTADVSGRCLSMLAQLGEMPQGSEPAQRAFAYMLQEQESDGSWYGRWG
LNYIYGTWTALSSLNAAGMPHDDPRMKRAVQWLLSIQNDDGGWGEGGESYKLDYRGYERA
PSTASQTAWALLGLMAAGEVNHEAVARGIDYLQREQREHGLWDETRFTATGFPRVFYLRY
HGYRKFFPLWALARFRHLKREGLTRVTVGM
>A0A6P0ZXC1|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO1F2|TrEMBL
MQTQDRIVNSGVTEAIANSQSYLLAQQYPDGYWWAELESNVTITAEIILLHKIWGTDKQR
PLHKAEAYLRSQQRKHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDSALVRARDFILR
RGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPQWFPFTIYEMSSWARGSTVPLLI
VFDQKPVFDIQPSITLDELYTEGADHAKFELPRNSDWTDLFVLLDHGFKLAEDLNLVPFR
KQGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPVVQRGLEAIDRFAIE
TPDSYRVQACVSPVWDTAWVLRAMVESGLEPDHPALVRGGEWLLQQQILDYGDWVVKNPQ
GKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLKQAAIARGLAWIASMQCNQGGW
AAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEMLGSCNLSIESQQLEKAIAFLIQ
EQEADGSWFGRWGVNYIYGTSSALSALSKIAPHTHQRSIERGAAWLVKCQNLNGGWGETC
LSYDDPSLKGLGISTASQTAWALIGLMAAGEATGNWARDAIDMGVNYLVSTQQPDGSWDE
TEFTGTGFPSHFYLKYHFYQQYFPLLALGRYQMSVSS
>B2IWZ4|squalene-hopene cyclase|EC 5.4.99.17|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MQTQDRVKVNQVAEAIAASQQYLLSIQNPAGYWWAELESNVTITAETVLLHKIWGTDQTR
PLHKVEAYLRQEQRQHGGWELFYGDGGELSTSVEAYMALRLLGVPATDPAMIRAQAFILQ
RGGISKTRIFTKLHLALIGCYNWRGIPSLPPWIMLLPKAFPVNIYEMSSWARSSTVPLLV
VCDRKPVFITDPTINLDELYAEGIDRVRWELPQSGDWTDLFLTLDQGFKWAESLNLVPFR
EEGIKAAEKWILERQEATGDWGGIIPAMLNSMLALRCLDYDRSDPIVERGLQAIDNFAIE
TDNSYRVQPCVSPVWDTAWVMRALVESGFVPDHPAVVKAGEWLLQKQILDYGDWAVKNRQ
GKPGAWAFEFENRFYPDVDDSAVVVMALHLAKLPNEKIKQAAIARAVNWIASMQCKPGGW
AAFDLDNDQDWLNSIPYGDLKAMIDPNTADVTARVVEMLGACDLSIDSDNLERSLTYLLR
EQETEGCWFGRWGVNYIYGTSGVLSALALIDPQRHKLSIERGAAWLLGCQNLDGGWGETC
RSYDDPSLKGKGDSTASQTAWALIGLLAAGEATGKLAVKAIEQGIGYLMATQQPDGTWFE
ANFTGTGFPCYFYLKYHLYQQYFPLIALGRYQAAIKES
>A0A4Q2U0W0|squalene-hopene cyclase|EC 5.4.99.17|Lichenibacterium minor|TrEMBL
MSLAAVAAHQPAAVPASVIDDLDLAIDRAALALRREQRGDGHFAFDLEADATIPAEYVML
KHFLGETDPVIERKIGAYLRRTQEAHGGWPLLHGGALNVSASVKAYVALRMIGDSVEAPH
MARARDAILAAGGAAHSNVFTRTSLALFGMVPWRAVPVMPIEIMSAPAWFPFHIYRISYW
ARDTLVPLLVLMALKPKGVNPRGILIPELFVTPPERVRIWPKGTNQVGGWGIIFGALDKV
LQAAEPYFPKGKRQSAIDKAVAFVRARLNGEDGLGAIYPAMANTVMMFRVLGVPDDHPDA
VLARSAVDKLLAIKGEEAFCQPALSPVWDTALSAHALIEAGGDHAEAADRGLAWLKPLQV
LDVKGDWAEQRPDVRPGGWAFQYRNDYYPDLDDTAVVAMAMDRARGQSGDAGFDESIARA
REWVVGLQSKDGGWAAFDADNTSTYLNYIPFADHGALLDPPTSDVTARVVSMLAQLGETP
AASPAMKRGIDFLLAEQHPEGGWYGRWGFNYVYGTWSVLCALNAAGFPSDAPQVRRAVAW
LASIQNADGGWGEDDKGYDLDYKGYNPAPSTASQTAWAVIGLMAAGEVDHPAVERGVAYL
RSTQTADGFWPEELFTGTGFPRVFYLRYHGYPKFFPLWALARYRNLKHSNSRTVMVGM
>A0A7K2VEV5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID1328|TrEMBL
MTATTDGSTGATIPPRAAAASDTDSTDPLAAGVPEAAERAAARATEFLLARQDPEGWWKG
DLETNVTMDAEDLLLRQFLGILDAATTRATAQFIRGAQREDGAWATFYGGPGDLSATVEA
YVALRLAGDAPDAPHMARASAWVRERGGIASARVFTRIWLALFGWWKWEDLPELPPELIW
FPTWLPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPANPNPPKPFAPLAS
WDGAFERLDRVVHRLRKAVPRRVRRAAMNAAARWIVERQENDGCWGGIQPPAVYSVIALH
LMGYDLRHPVMRAGLESLDRFAVWREDGSRMIEACQSPVWDTCLAVIALADAGVPADHPK
LLKAADWMLAEEIRRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVALALRRVSHPQ
PERVDGAIARAVRWNFGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMMAAEGLAHDPRTRRGIAWLLAEQEADGSWFGRWGVNYVYGTGSVVPALTAAGLPASH
PAIRRAVHWLQQAQNDDGGWGEDLRSYKYAREWSGRGASTASQTAWALMALLAAGERDSE
AVERGVRWLADTQRDDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFDK
APLAARRGVRATAGGS
>A0A7T1WQW9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces bathyalis|TrEMBL
MTATTDSGAGAMATAVSAGPESLPGRAQRAAGLAVENLLARQDAAGWWKGDLETNVTMDA
EDLLLREFLGIRDEKTTREAARFVRSQQRQDGTWATFHGGPGDLSTTIEAYVALRLAGDR
PDAPHMERAAAWVREQGGVAASRVFTRIWLALFGWWRWADLPEMPPEMIWFPKWFPLNIY
DFGCWARQTIVPLTVVCAKRPVRAAPFSLDELHRDPADPNPSRGMAPAASWEGFFQRLDR
SLHAYRKVASRSLRRAALRSAARWIIERQENDGCWGGIQPPAVYSLIALRLLGYDLDHPV
MRAGLSALDSYTVRYEGGRDGDPGEAHDGPMRMVEACQSPVWDTCLATIALADAGVAPDH
PALVKAADWMLGEQVLRRGDWSVRKPQLPPGGWAFEFHNDNYPDTDDTAEVVLALRRVRH
HDRTRVDTAVRRAVRWSLGMQSRNGAWGAFDADNDSPFPNRLPFCDFGEVIDPPSADVTA
HMVEMLSAEGRRDDTRVRRAVSWLLSEQEVSGAWFGRWGVNYIYGTGSVVPALVAAGLPV
SHPAVRRAVYWLESVQNGDGGWGEDLRSYRPGHEREWAGRGTSTASQTGWALLALLAAGE
RDSMAVEQGINWLVRTQRDDGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRYLYGP
GTGTGRQEER
>A0A7C4MU09|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MKADDSFAGSGLADESLDSSTNSSTGADASCERQCLTGAVRGAIESTRRWLLAQQLPDGC
WCAELEGDTILESETILLWAFLGCSDSEDACRAAEYIRRRQLPGGGWAMYPGGAVEISGS
VKAYFALKLTGHDPGAEYMQRARAAILAHGGADAVNSYTRFFLALLGQIPYDQCPEVPPE
AVLLPRWFPVSLHQVSSWSRTIIVPLSIVSAYRPVRQLPAELGIRELFLREPRDWPPLRC
PGLPGGTGLFSWDRFFRGVDRALKFCRRRRLLPLRRRAIQAATNWMLERFEGSDGLGAIY
PPIVWSIIALRCLGFPDDHPAVVYNHQQLRDLMIADEQEGSLRLQPCKSPVWDTAIAVRA
LAAAGVPPQSREMRLAAHWLIERQIRRPGDWSNMVRAEPGGWCFEYRNDFYPDNDDTAMV
LMALQTQFEPPAASAQWAPTLRAARQGTSDDDSGDVLSRLAGAIDRGMRWMLAMQNDDGG
WGAFDRNNNRQFLCYVPFADHNAMIDPSTPDLTARVLEALGKLGLTRAHPAVGRGIEYLR
RTQEADGSWFGRWGVNYIYGTWQALVGLRAVGVAAEDPAVVAGARWLLAHQQPCGGWGES
PESYEHPHLRGQGAPTPSQTAWALLGLMAAGLEDHPAVARGVRYLAATQLPDGTWAEPEF
TGTGFPRVFYLRYHYYRIYFPLLALSQWAATIPLNS
>A0A4R4LGE2|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. KC216|TrEMBL
MTTTDVSGLTGAAAAAVDAARDHLLGLQSPEGWWRGELETNVTMDAEDLLLRQFLGIRSE
SETAEAARWIRSQQREDGTWANFHGGPPELSTTVEAYVALRLAGDPVDADHMRRAAKYAR
DAGGIEATRVFTRIWLALFGQWSWDDLPVMPPELMYLPRRVPLNVYDWACWARQTIVPLT
VLGSLRPVRALPFDLPELRSGVRPVKDEKGWGRFFNGLDRVLHVYEKRPVRPLRTAAMRR
AADWIIARQEADGCWGGIQPPWVYSLMALHELGYGLDHPVIRRGLDGLERFTIRDEKGRR
MEACQSPVWDTVLAMNALGDAGVPADDPAMRRAAAWVVGEEIRGPGDWSVRRPGLPPGGW
AFEFDNDIYPDTDDTAEAILALRKVDLPEAEAPIGRAVRWLEGMASRDGGYGAFDADNTQ
DLCNKLPFCDFGAVIDPPSADVTAHVVEALCGEGRAESPTVKRAVVWLLKAQEADGSWFG
RWGANHVYGTGSVVPALVAAGVGRGKSAIRRAVAWLERHQNDDGGWGEDLRSYDDPAWIG
RGASTASQTAWALLALLAAGERSPAVDAGVRWLVDHQRPDGTWDEDQYTGTGFPGDFYIN
YHLYRLVFPISALGRYLPKEVRTS
>A0A4R5VL60|squalene-hopene cyclase|EC 5.4.99.17|Bacillus salipaludis|TrEMBL
MITASKGIDWIVGKLKNDQSPDGSWNYPFETGISTDAYMIILLRTLELHDEELIQGLAER
LLSRQEKNGAWKIFYDEGEGNLTATIEAYYALLYSGYYQKNDRRLRAAKIFILANGGLEE
ASMYTKVMLAITGQYNWPKFSPMPVEIILLPLSFPVNFYSFSVFGRANLTPIMILADKKF
TLTTAKSPNLSELQIDRNTPDPWIRTSEMRSLFSFLEDGVKNLLGLPGDLHRLAIERAKK
YMLDRIETDGTFYSYYSCTFLMIFALLSLGYKKTDPIIINAVNGIKSMKCEIKGLPHMQY
TTANVWNTSLIGYALQGAGIVPEDPMIVRANQYLLERQHHKFGDWVIHNPNSLPGGWGFS
HVNHILPDVDDTTASLRSISRIASTHLNTWDRGINWIFSMQNDDGGWAAFEKNVNSKIVE
FLPVEKGKYMLLDPTCADLTGRTLEFFGNFTNLSRNHEDVKKAVKWLIKNQEKNGSWYGR
WGICYLYGTWAAITGLLSVGVPAAEPAVVKAVNWLKSTQNDDGGWGESCHSDNQETYVPL
RASTLTHTAWALDALIAATDQPTKEIDRGISYLLASLEKEDWTIDYPKGQGMAGAFYIHY
HSYRYVFPLIALTHYQKKFGY
>A0A4R0Y750|squalene-hopene cyclase|EC 5.4.99.17|Roseococcus sp. SYP-B2431|TrEMBL
MPNLPGSAALASQGGSPSLDSQGPDNQTLEQAVASAAQHLLAHQRADGHWVFELEADCTI
PAEYVMLHHFFGRIQPEKEARIARYLRRVQSDQLGNCNGGWPLFHGGPLDISCSVKAYLA
LKLIGDPADAPHMVAARRAILAAGGAERSNVFTRSTLALFGAVPWRAVPMMPPEIMLLPR
WFPFHVSKISYWARTVLIPLTVVIARQPKARNPTGATIDELFTTPPEQVKEWPGGAHQAE
PWASLFKGLDGALHRARTLFPRTHRMRAEAACERFVTERLNGEDGLGAIYPAMANAVMMY
HCMGVAEDDPRLVTAWSSIEKLVQERGPASGAGQEDAGETYVQPCLSPVWDTALASHALL
EAGGGEERSAVARGLDWLLTKEITEVRGDWSWQRPSLEPGGWAFQYENAHYPDVDDTAVV
VLAMDRFRKESGDGKEYDPAVKRATDWTVGMQSKGGGWGAFDADNTFHYLNHIPFADHGA
LLDPPTADVSGRCLAMLAQLGRGEEAASKQAIEYLLREQEADGSWYGRWGVNYVYGTWSA
LTALNAAGLPHGHQAMRRAVAWLVERQNEDGGWGEDGMSYPTRGGTRPDSQQHAPSSASQ
TAWAILALMAAGEADHPAVQRGAEWLTRHQKPDGDWPEEDYTGTGFPRVFYLRYHGYRRI
FPLWALARLRNLRASNTRRVSHGL
>A0A2Z4V1Z2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. ICC1|TrEMBL
MTATTDGGAGADACDAGPGDGVAAGPPGRGHATRPAVRTEPAAAPGPDDRAVREATLRAV
RNLLDRQDEAGWWKGDLETNVTMDAEDLLLRQFLGIRDEATTQAAALFIRGEQGADGTWA
TFHKGPSDLSATIEAYVALRLAGDDPGAPHMARASAWIRGHGGIAGARVFTRIWLALFGW
WNWDHLPELPPELLFLPPWVPLNIYDFGCWARQTIVPLTVVSALRPVRPAPFALDELHTD
ARNPYPVKRLDPLASWGGAFQRMDKALHLYRRFAPRRLREAAMASAGRWIVERQEDDGCW
GGIQPPAVYSVIALHLLGYDLGHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLA
AIALADAGVRPDHPALVKAADWMLGEEIRRSGDWAVRRPRLAPGGWAFEFHNDTYPDIDD
TAEVVLALRRVKHPDPARVEAAIARGVSWNLGMQSKNGAWGAFDADNTSPLPNKLPFCDF
GEVIDPPSADVTAHVVEMLAVEGKAGDARTRRGIAWLLAEQEPEGGWFGRWGTNYVYGTG
SVVPALTAAGFALSHPAIRRAVGWLESVQNEDGGWGEDQRSYKDPSWAGKGASTASQTAW
ALMAMLSAGERDGESVRRGIAYLVSTQGEDGGWDEPYFTGTGFPWDFSINYHLYRQVFPV
TALGRYLYGEPFGPEGRYPDPGAAQAVQAAEEA
>A0A535MGI5|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MGTALVTAAAVPLPARPPRAGSLAPEAERLDRACERARDGLLAQQRADGHWSYRLQSNVC
MEAEYLLLGRILGRADPDRERRLIARILDDQLPDGGFPTYAAGPADADVTVEALAALRAA
GLPSGHPRVAAARAAAERLGGVAATRVFTRMWLACVGLRPWEGLPELPPEMLFLPGRGPL
GLMRFASWARATIVPLTVVLTLRPQCDAVVLEPGALPEGAPGGPRRPVPSGPLASAFLGV
DRVLAAYRRLPHQPGRGRALARAEAWIVDHQDVDGAIGAIQPPMAYQCLALHALGHRRGS
PALERAWSAFEGFVLDDGERCEMQACVSPVWDTALAMCALADLGVAPDDEAMRRAARWLL
AEEVRVRGDWARTRPHLPAGGWAFEYHNDLYPDVDDTAIVLCALGGADVEGRDDAVLRGL
RWMLGMRCRDGGVAAFDAENTSRLVGRIPFCDFGAVTDPPSADVTAHVLEAAARWGLSAT
HRDVTAMRAWLLRHQESGGSWFGRWGVNHVYGTAAAIPGLTAAGLHRLHPAVQRGVAWLL
RVQREDGSFGEDCGSYRDPALIGRGEPTASQTAWGLQGLCSGGEAGSGAAARAARWLVEQ
QGADGLWSDSRFTGTGFPGDFYLGYHGYAAYFPAAALGRYRRSRPVGGAHSTGRAPIKLT
GALSEALV
>A0A7C3KB12|squalene-hopene cyclase|EC 5.4.99.17|Oscillatoriales cyanobacterium SpSt-418|TrEMBL
MLTQNPVTQTSIKTAIARCQEYLLSLQKPEGYWWANLESNVTITAEGVLLYKIWGIEATI
PLDKAKNYLLGEQRDHGGWELFYGDGGELSTSVEAYMALRLLGVSPDEPAMKRAKAFILA
KGGVTKTRIFTKFHLALIGCYDWRGIPSIPPAIMLLPDQFPVNIYEMSSWARGSTVPLLI
VFDQKPVYPMGISLNELYVEGTQQNYELPRKGDWTDVFIMLDSAFKLAEDWQLMPFREEG
LKAAEKWVLERQEATGDWGGIIPAMLNSLLALRSLGYNVDDPIVERGFRAIANFSVETDE
IFWVQPCVSPVWDTALVMRSLVDSGLEPDHPALVKGAEWLLDKQILDYGDWAVKNRKGAP
GAWAFEFDNRFYPDVDDTAVVVMALKAVKTPFENRKQRAILRAVNWIASMQCTPGGWAAF
DINNDQDWLNDIPYGDLRAMIDPNTADVTARVLEMAGRLGVDATVQETNLSQTAIDQAIA
YLNREQEPEGCWFGRWGVNYVYGTSGVLSALSLVAAKTECKQIERGAAWLVSCQNADGGW
GETCWSYNDPSLKGQGKSTASQTAWALTGLLAAGDATGEYALTAIRRGVDYLLSHQNPDG
SWDELEFTGTGFPQHFYLNYNYYRLHFPLTALGRALQVLEQAGN
>A0A839P6A7|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium sp. R2-1|TrEMBL
MREAAASKVETLQRPKTRDVSLDDVERGVQSATRALTEMTQADGHICFELEADATIPSEY
ILFHQFRGTEPRPGLEAKIGNYLRRTQSKVHGGWALVHDGPFDMSASVKAYFALKMIGDD
IEAAHMRAARKAILQRGGAANANVFTRILLALYGEVPWTAVPVMPVEVMHLPKWFPFHLD
KVSYWARCTMVPLFVIQAKKPRAKNPRGVGVAELFVTPPDSVRTWPGSPHATWPWTPIFG
AIDRVLQKTQDHFPKVPRQRAIDKAVAWVSERLNGEDGLGAIFPSMVNSVLMYEVLGYPS
DHPQVKIALEAIEKLVAEKDDEAYVQPCLSPVWDTALNSHAMLEAGGAQAEANARAGLDW
LKPLQILDIKGDWAETKPNVRPGGWAFQYANPHYPDLDDTAVVVMAMDRAQRQHGLVSGM
PDYSTSIARAREWVEGLQSADGGWAAFDADNNHHYLNHIPFSDHGALLDPPTADVTARVV
SMLSQLGETRETSRALDRGVTYLLNDQEKDGSWYGRWGMNFIYGTWSVLCALNAAGVDPQ
SPEIRKAVAWLIRIQNPDGGWGEDASSYKLNPEFEPGYSTASQTAWALLALMAAGEVDDP
AVARGVNYLVRTQGADGLWSEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKRGNS
RQVQFGM
>A0A6G2ZYE9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4915|TrEMBL
MTATTNGPAGAAPSRPAPARTTAATTDTAALDGAAVEAAAERARARAADHLLGLQSPEGW
WKGDLDTNVTMDAEDLLLRQFLGIRDEATTRSAALFIRGEQREDGTWATFHGGPPDLSTT
VEAYVALRLAGDSPDAPHMTRAAHWVRSQGGIAEARVFTRIWLALFGWWPWDRLPELPPE
LIFLPPWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPADPAPRARFAP
LASWNGAFQRLDRALHAYRKVAPRALRRAAMATAGRWIVERQENDGCWGGIQPPAVYSMI
ALHLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALADAGVPAD
HPQLVRAADWMLDEQIERPGDWSVRRPHLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVR
HPDTARMERAISLGVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDPPSADVT
AHVVEMLAAEGLAADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALVDAGLP
TTHPAIRRAVAWLESVQNDDGGWGEDLRSYREQGRMARGASTASQTGWALMALLAAGERE
SRAARRGVTFLAETQHEDGSWEEPYYTGTGFPWDFSINYHLYRQVFPLTALGRYTRGAAP
EGA
>A0A551XZ89|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa Ma_QC_C_20070703_M131|TrEMBL
MQIQDKITEIAAQTAKAIELSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPLNDPALEKAREFI
LAQGGISKTRIFTKMHLALIGCYDWLGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKTVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTNLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKAVDNFAIE
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKAVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A8I0R8U6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces albidoflavus|TrEMBL
MTATTNGPAGAAPSSPAPARTTAATTDTAALDGAAVEAAAERARARAADHLLGLQSPEGW
WKGDLDTNVTMDAEDLLLRQFLGIRDEATTRSAALFIRGEQREDGTWATFHGGPPDLSTT
VEAYVALRLAGDSPDAPHMTRAAHWVRSQGGIAEARVFTRIWLALFGWWPWDRLPELPPE
LIFLPPWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPADPAPRARFAP
LASWNGAFQRLDRVLHAYRKVAPRALRKAAMATAGRWIVERQENDGCWGGIQPPAVYSMI
ALHLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALADAGVPAD
HPQLVRAADWMLDEQIERPGDWSVRRPHLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVR
HPDTARMERAISLGVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDPPSADVT
AHVVEMLAAEGLAADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALVDAGLP
TTHPAIRRAVAWLESVQNDDGGWGEDLRSYREQGRMARGASTASQTGWALMALLAAGERE
SRAARRGVTFLAETQHEDGSWEEPYYTGTGFPWDFSINYHLYRQVFPLTALGRYTRGAAP
EGA
>A0A832UFW2|squalene-hopene cyclase|EC 5.4.99.17|Nitrospinae bacterium|TrEMBL
MEESFVSPDGVSVNEDMLHRSIEKSREYLLFHQNEKGYWVDELEANVTISAELIFFMHFT
DRLDSERQQKIVNYLLYMQREDGSWPLFHGGLCDINSTVESYMALKMAGVPGDREEMVRA
RNAIHINGGIKKTRVFTKIFLAMFGQLSWDVCPAIPAEIILLPNGFFFNIYEISSWSRGT
VVPLSVMRSLEPVHSLPAGRDVQELFTENDNDLDFKPSGLPFTSWRDTFIYLDRIIKLIG
KFPWKPCRKMALRAVEKWILEHQEEEGDWAGIQPAMLNSLLALHLMGYPKDHPACVKGME
AVDRFLLEKEDRLWMQACVSPLWDTAICLNALIDSGMPTDHPALIKSAEWILTKQVVKRG
DWQIKKPHAEPGGWAFEFYNELYPDTDDTAEILLALNRIDVPDIRWKLNECQRALSWLLN
MQSKNGGWGAFDVDNDKEVLNEIPFADHKALLDPPTVDVSSRILWMLSQWGFKREHPQVA
RALKFVKEGQELDGCWFGRWGVNYVYGTFLAMTGLSAMGEDMSQPFSRKAIQWLGVHQNE
DGGWGETCQSYEEPSFRGRGTGTASQTAWALLALVAGGEAKGDAAKRGVEFLMCNQNDQG
TWSEDEFTGTGFPVHFFIKYHMYQHFFPLMALARYRRAIEND
>S7SXH4|squalene-hopene cyclase|EC 5.4.99.17|Geobacillus sp. WSUCF1|TrEMBL
MDDERRVLIDALKQSQAADGSWRFPFETGISTDAYMIILLRTLGIHDEPLIQALVERIES
RQDPNGAWKLFADEGDGNVTATTEAYYALLYSGYRKKKRPAYAKGESAHFGNGRPRACPL
VYESDARIDRTASVAKTVSAAA
>A0A4R9F3Y1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. MZ04|TrEMBL
MTATTDGSTGAVTPRAASASQPIDTTAATAGALDAAARAIQRSTDFLLAQQDTQGWWKGD
LDTNVTMDAEDLLLRQFLGIRDERTTRAAALFIRGEQRDDGTWATFHGGPAELSTTVEAY
VALRLAGDAPDDPHMAKASAWIRDQGGIAASRVFTRIWLALFGWWKWDDLPELPPELIYF
PKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHSDARRPNPGKPLAPMASW
DGVFQRLDKALHLYHKVAPRSVRKAAMNSAARWIVERQENDGCWGGIQPPAVYSVIALHL
LGYDLEHPVLKAGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHPQL
VKAADWMLDEEIRRPGDWAVRRPRLAPGGWAFEFHNDNYPDIDDTAEVILALRRVEHPDR
ARLENAIGRGMRWNLGMQSKNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGKAHDPRTRRGIEWLLAEQEADGAWFGRWGVNYVYGTGSVVPALTAAGLPGSHP
AIRRAVGWLESVQNDDGGWGEGLRSYRYEEWRGHGASTASQTAWALLALLAADERDGKAV
ERGIAFLAETQLPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGDPFAALS
GKSSGKLSGKGS
>A0A523NKI0|squalene-hopene cyclase|EC 5.4.99.17|Nitrospina sp|TrEMBL
MPDQKPEIVENPATAPAATAAPGTPLDRAIGRAKAYLLSLQHADGYWLAELESNATMIAE
YVFFMHFMGIWDPRRVEQCQNTLLKTQQADGGWPLFYGAPSDISTTVESYVALRMAGMSP
KAKAMARARKCIAQLGGVRNARVFTKIFLAMLGQSAWDDLPAMPVEIILLPKSFYFNIYE
MSSWSRGTVVPLTIVAAHQPVWPLKPEHTVPEIFTEADRDLSVQSKKKGLNWPNLFLKID
QLIKFLGKSPVKPFRSWALKRALQWTLDHQEPEGDFSGIQPAMLNSMLAMKLMGYGNDHP
LMVKGYQAIDRFIIDRGDHLIFQACVSPLWDASIACNALMDAGLPGDHPAIVKAGEWMLR
KQVTRPGDWTVKNPNTPPGGWAFEFYNEPYPDCDDTAEILMALDRTGIPDTEWKRKEMQR
AFTWLFSMQSKNGGWAAFDQDNDHELFNRIPFADHGAMLDPPTVDVTGRVLWMLGRINHN
VNDPMVQRALQFIKREQESDGCWFGRWGVNYIYGTWLVLTGLRSIGEDPSQSYIRKAAEW
LKAHQNKDGGWGETCQSYAEPSLRGKGKSTHSQTAWAVMGLIEADEPHSNAVKRGIEYLV
RNQQEDGSWYEDEFTGTGFPRHFFIKYHLYQIFFPLMALARYRNKTG
>A0A6N6S688|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Brocadia sp|TrEMBL
MRNFLLSLFERLETSVYKFNGNGNGNGKHPVPDLSKDNLRFESLPMRTNIHASSAVKNPL
DTGILRSQRYLLRNQNQSDGYWVGILEADTTITSEYIMVMHFLGKIDREKQKMAANLLRE
HQLSDGGWNIYYGGPSEISASVKAYFALKLAGYTADEPFMQRARKCILDKGGIMKANCFT
KIYLAMFGQIDWQAVPAVPAEMILFPPGFYFSIYEMSYWSRCIVVPLSIAIAKKPYIPVG
DDLLKELYVIPREKVVYRIKRDQSGLSWHNFFIDADSIFRRYEQHPIQCIRRIALRKAEE
WMLDHLEKSGGLGAIWPAIVNSIFAMKCLGYQDDHPAFVKQLQEIEDLIVYDGNKLYLQP
CVSPVWDTAWAIIALHESGIAGADPALQRAGQWLLSKEVRNFGDWALKCKVDEPSGWYFQ
YANEFYPDTDDSAAVLMALQRVSLPEKAGKEASFLRAIRWILAMQCDDGGWGAFDRNNNK
TILNHIPFADFNALLDPSTSDVAARCLEFLGRIGFGKSSQHARKAVEFLQKEQEKDGSWF
GRWGANYIYGTWSVLSGLFAVGEDMNLPYIKKAIEWLKSVQNSDGGWGETIQSYNDPFLK
AIGKSTPSQTAWAILGLLAGGETKSEAVERGIKFLLAKQKEDGTWDETEFTATGFPKVFY
LKYHLYRNYFPLIALSRYRNSLQKK
>T2AZ50|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVGARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGRWG
>A0A3A1V6A3|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus nanensis|TrEMBL
MMKQVNREIDRLINKLTASQRQDGSWHFCFENGTIIDAYVILLFRCLERNDEPLIQKLHD
RILSQQQPEGCWRLYRDEEGGNLPATVEAYYALLCSGYSKPGDPAIERARAFILSHGGAD
KAASILTKALLSATGQRKWPLSLTSIPIEAMLIPDFMPLNLYSFSGYARVHLVPLLVMAS
LGFSVKTAQMPDLSELLETRGDEEEPLPEAHLHLEATLRSGTARLIGSPRSLRAAALDKA
ERFMLERTEADGSLYSYATSTILMVFALLALGYGKDHPVIEKACQGLKDMQFDIGGSTTL
QNSPSTVWDTALLAYAMQEAGVPRSEPVIQKAAAYLLGKQHTRKGDWVKHNPNAEPGGWG
FSATNTRNPDVDDTTAALRAISRFAKADNRFQDAWNRGLSWTLSMQNKDGGWPAFEKNTD
NRILTWLAIDGAKSAAIDPSAADLSGRTLEFLGNYAKLDTSHLFMRRGADWLIYNQERDG
SWYGRWGICYLYGTWAALTGLMAAGVSPEHEAVRKGVKWLLETQNEDGGWGESCRSDAER
RYVPLGASTPSQTAWSLDALIAASPQSKSEIDRGVRRLLALLHEDDWTTDYPTGAGLPGV
FYIHYHSYRYIWPLLALAHYRRKLGD
>T2AYI8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQTLIETEYKQHVSTEIETALNWLKEQQLSDDPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGRW
G
>T2B028|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPGLSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRATALLSLADKKIYEKNINDGVNYIKSEQEEDGSWFGSW
G
>T2AZD8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGIACNALMDAGLPKDHPALIKATEFFFRKQVVKRGDWQVKNPNAESGGWAFEFY
NELYPDNDDTAEILMAIHSIEFPDLRYKLKESQRALSWLLSMQSKNGGWGAFDQDNDQEL
FNAIPFADHNAMLDPPTVDVTSRIIWLLGILGYSREHPQVKKAIVYIISDQEDDGSWFGR
WG
>T2AYF4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAICSNALLDSGLPTDHPALVRAGKWTVSKQVTKRGDWQVKNPKAEPGGWAFELY
NELYPDTDDTAEILLFLNRVEILDNRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGKWGFNKQHPQVKRAIKFVKERQEVDGCWYGR
WG
>T2AZS3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAALALQEADPKGTRQSREKAYNWLKTKQLDKQSGDWQIRQPHLEGGGWAFQF
ENPHYPDVDDTAVVAFAMANADLPNLNESINRATRWTAGMQSKNGGFGAFDCDNTDYYLN
HIPFADHDALLDPPTADVSARCAMLLGHQIKNHPEYQTTLDDTIAYLRSEQETDGSWFGS
WG
>T2B058|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTSLATHAMLEANLSSGLRILENDSTSKACKWLENLQIKNCAGDWSVWRPNLRPGG
WAFQYHNDYYPDIDDTAVVAMALHRTGNKIYEPALLRAAEWIIGMQSKNGGWAAFDADNE
YHLLENMPFADHGALLDPPSVDVSARCISFLTQLGYDQTNGTIKHGIKYLKKNQEEDGSW
YGSWG
>A0A653MLS0|squalene-hopene cyclase|EC 5.4.99.17|Bacillus mycoides|TrEMBL
MLLYDKVHEEIERRTTALQTMQRQDGTWQFCFEGALLTDCHMIFLLKLLGRNDEIEPFVK
RLVSLQTNEGTWKLYEDEKGGNLSATIQAYAALLASEKYSKEDMNMRRAEMFIKEHGGVS
RAHFMTKFLLAIHGEYEFPALFHFPTPILFLQDDSPLSIFGLSSSARIHLIPMMICMNKR
FRVEKKLLPNLNHIAGGGGQWFREERSPLIQSFLGDVKKVISYPLSLHHKGYEEVERFMK
ERIDENGTLYSYASATFYMIYALLALGHSIQSPIIEKAVTGLKSYIWKMDRGSHLQNSPS
TVWDTALLSYSLQEAKVTNENKMIQRATEYLLQKQQTKKVDWSVHASSLVAGGWGFSDVN
TTIPDIDDTTAALRALARSRGNDRVDDAWGRGVEWVKGLQNNDGGWGAFERGVTSKLLSN
LPIENASDMITDPSTPDITGRVLELFGTYAPNELLEEQKKKAIKWLMDVQEQNGSWYGKW
GICYIYGTWATMTGLRALGVPSTHPALKKATSWLEHLQHEDGGWGESCQSSVEKKFISLP
FSTPSQTAWALDALISYYDQETPIIRKGISYLLAQSTMNEKYPTGTGLPGGFYIRYHSYG
HIYPLLALAHYVKKYRK
>T2AZL4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTALVSQALIETEHKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPGLSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSKPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWFGSW
G
>T2AZJ1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTALVSQALIETEYKQHISTEIETALNWLKEQQLSDELGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAITLLSLADKKIYAKNIKDGVDYIKSEQEEDGSWYGSW
G
>T2AYM8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTCIAQLALIESGIAADDHMVQSSARWLMDKQIFARGDWQVRAKKTRPGGWSFEFD
NLAYPDIDDASIVVMALDKVKLPDNEEPRRADSIQRGVEWMAGMQSKNGGWAAFDKDNNK
KYLTKTPFSDFGETLDPPSVDVTAHLLEMYGRLGYTKDDPAVARGLKYVISEQEEDGSWF
GSWG
>T2AYG9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPGLSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSKPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGRW
G
>T2AXL7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PVWDTGIACNALMDAGLPKDHPALIKATEFFFRKQVVKRGDWQVENPNAESGGWAFEFYN
ELYPDNDDTAEILMAIHSIEFPDLRYKLKESQRALSWLLSMQSKNGGWGAFDQDNDQELF
NAIPFADHNAMLDPPTVDVTSRIIWLLGILGDSREHPQVKKAIVYIISDQENDGSWYGRW
G
>T2AXQ4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAAHAVLETLGGNTLLLNKSCDWLSKLQIKEHTGDWGWRRKGLRPGGWAFQYN
NKFYPDVDDTAVVGMALHRQNPEKYADTISRAEEWIIGMQSPNSGWAAFDADNEYYLLEN
LPFADHRALLDPPTADVTARCISFLTQIGTSNNHPISRGLEFLKRNQEEDGSWYGRWG
>T2AYE7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAIATIALRDAGVPAEHPSLRRTVDWLLEKEVRRPGDWTVRNIETEPAGWYFEFN
NEFYPDVDDTCMVLMALARCLPDQPEWDTDFLVDDWSPHEADKDATAVLAARNADSVLAA
VQVDRLRPMLGAMHRGVRWILAMQSKDGGWGAFDRDNVRELFTQVPFADHNAMIDPSTAD
LTARMLEMFSYLNVPADHPVVRRAIDFVWKDQDPEHCWYGSWG
>T2AYB7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PVWDTSLATHAMLEANHSSGPRILENDSTSKACKWLEKLQIKDCAGDWAVWRPNLRPGGW
AFQYHNDYYPDIDDTAVVAMALHRTGNKIYEPALLRAAEWIIGMQSKNGGWAAFDADNEY
HLLENTPFADHGALLDTPSVDVSARCISFLTQLGYDQTNGTIKRGIEYLKKNQEEDGSWY
GRWG
>T2AZQ0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLATHAMLEANLTSGPRTLDSDNISKACKWLANPQIKDCRGDWAIWRPNLRPGG
WAFQFRNDYYPDVDDTAVVAMALHRTGNKSYEPILQRAAEWIIGMQSKNGGWAAFDADNE
YHFLENMPFADHGALLDPPTADVSARCVSFLTQMGYDRSHDAIKRGIEYIKKRQEKDGSW
YGRWG
>T2AZK4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAIAANALLDSGLPSDHPTLLKAGEWIINKQVVKRGDWQVKNPGAEPGGWAFEFY
NELYPDTDDIAEILIFLNRIDIADNRWKLRECQRAIDWLHSMQSKKGGWGAFDVDNDQEV
LNEIPFADHKALLDPPTVDVTGRILWMLSKWGFKKQHPQIQRAIQFVKDNQEIDGCWYGS
WG
>T2AZU4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAIVSIALRESGISEDDPQIRESCDWLIDREIRFRGDWYHKNPVEVEPSGWVFEF
NNKWNPDVDDTAMVLMALRQTPTDNQQRRDESFKRGMEWMKAFQCRDGGWAAFDKDCTKS
ILEKVPFADHNAMLDPECADITARILELLGYEGYPVDDPQVKRGLAYLRSQQETDGSWYG
RWG
>T2AZN0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALASQALIETGYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGRW
G
>T2B0H4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVASLQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAITLLSLADKKIYEKNIKDGINYIKSEQEEDGSWYGSW
G
>T2AZE5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLNDEPGDWRIQKPELSGGGWAFQ
YSNYHYPDLDDTSMVAWAMHRTNNKSYSELIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAITLLSLADKKIYAKNIKGGVDYIKSEQEEDGSWYGRW
G
>R9W202|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAITAHALRDTDTPKARAAVSRGLDWLVPLQILDVRGDWISRRPNVRPGGWAFQF
ANPHYPDVDDTAVVAMAMERADRENGTALYGEAISRGREWVVRMRSSDGGWGAFEPENTQ
YYLNNIPFSDHGALLDPPTVDVSGRCLSMLAQLGETLLNSEPARRSLDYIVSDQERDGSW
YGRWGLNYIYGTWTALSALNAAGLPPTDSRMKRAAQWLISIQNADGGWG
>R9VY59|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAQVLSPVCDCGLPRNDERLMKAADWLLSKEIRYKGDWSHNVKVEDPSCWCFFFN
NDHQPDVDDTGEVLLALNSVDNPRERYQHEATQRAIHWVFAMQCKNGGWASFDKDNTKKI
FESIPFADHNAMIDPPTVDITGRILEMLASYGYTRRDPRVEKAIQFILQEQESDGSWFGR
WGVNYLYGTFLVLRGLQAMEFDHFEPAVQQAAEWIRMVQNPDGGWGE
>A0A431PFU4|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobiaceae bacterium|TrEMBL
MTLEDHNAGAAAPSAAAVDASIAAASSAVLDYRKPDGHWVFELEADATIPAEYVLLRHYL
AEPIDTVLEGKIANYLRRIQNENGGWSLFYGHEFDMSASVKAYFALKMIGDSPDAPHMKK
AREEMLRRGGAIKSNVFTRIMLALFGVVTWRAAPMMPVEIMLLPRWFPIHLTKISYWART
VIVPLLVLMNKKPRARNPLGVGIDELFLEDPKSIGMTAKAPHQSQLWFTGFNLLDKVLRV
VDPLFPKAPRQRAIDKAVAFVTERLNGVDGLGAIFPAMANTVMMYDLLGYPKDHPHYVLA
RQSIENLLVIKDDEAYCQPCVSPIWDTALTAHAMIEVGGEKEVASAKAALDWLKPKQVLD
VEGDWIEKRPGVRPGGWAFQYNNAHYPDLDDTAVVVMAMERARGTLNAGTKYDESIARGR
EWIDGLQSKDGGWAAFDADNLEYYLNNIPFSDHGALLDPPTEDVTARCVSMLAQLGETVK
TSEALARGVEYLRRTQLPDGSWFGRWGVNYIYGTWSVLCALNAAGVDHADPVMAKAADWL
IAIQNSDGGWGEDGNSYRLDYRGYEKADSTASQTAWATLALMAAGKVDHPATQRGIAYLI
QFQGKDGLWSEPQYTGGGFPRVFYLRYHGYSKFFPLWALARYRNLRNTNSRFVGIGM
>A0A842HC94|squalene-hopene cyclase|EC 5.4.99.17|Ruficoccus amylovorans|TrEMBL
MTPKPTDSASARPTKLIAGDAPKLLPVPASHYQTLTLDQSIQGALDWLARNQKPDGSWND
ILESNCCMEAQWVLAMHFLGRTDDPKYDKIIKGIIHKQREDGSWDIYHDAELGDINTTIE
CYAALRSAGLGPDEEPVRRAREWIFAHGGLAKARMFTRFWLATIGEWPWDTLPIIPPEIG
RIPTWAPFNIYQFASWARATFMSMSIVSARRPVVALPPDRRLDELYPHGRENFDFSFPRR
LEGFWPTFFRTADKALHLWQKLPWKPGREKSIKLALEWIIRHQDADGAWGGIQPPWIYAL
LALHVEGYHPEHPVVAAGINAWNNHWSYERDDMIFIQASESPIWDTLLAMQAILDTGATW
ESFPQFEPALEYILDKQILTKGDWAMTVKDVECGGWAFERANTFYPDLDDTAVALTVLCQ
MRQIAPERYQKRITRAFARAEKWLRAMQSSNGGWGAFDKDNHTKALTQIPFCDFGEVLDP
PSADLTGHKLEALGLMGYDMSDPAVKRAVDYIMSEQEPEGPWFGRWGVNYIYGTGLVLPG
LQAVGFDMSDPRIRKCGQWLLDKQNEDGGWGETCGSYMDDALRGVGPSTPSQTGWALMAL
LAMNTHDYDESIQRGLDYLIRTQKNGTWEQKEYTGTGFPGYGVGERIALQGNTEALSQGR
ELARGFMINYNMYRHYFPLMAMARARKHFASA
>A0A5C8PKB2|squalene-hopene cyclase|EC 5.4.99.17|Vineibacter terrae|TrEMBL
MMDQISALDPTSVEDVIGKATAALLGQARDDGHWVFELEADATIPAEYILLVHYLGETPN
LELERKIGTYLRRIQGSHGGWPLFHDGAFNLSATVKAYFALKMIGDAPDAPHMARARQAI
LAQGGADKANVFTRIQLALYGESAWRDTPTVPAELILLPRWFPIHLFKMSYWARTVIVPL
LVLQALQPLARNPRNIHVPELFVPHGAHAANRAPHQSRGWSAFFGGLDRVLKLAGSLWPK
GLRRRAIERCRAFVTERLNGEDGLGAIYPAMANSVMMFDALGYPETHPDRAIARLSVEKL
LVIKDDEAYCQPCVSPVWDTALMCHALMEVRSEAADTAAMRGLEWLKTRQVLDVKGDWAE
ERPDVRPGGWAFQYNNAHYPDLDDTAVVVMALDRARATVAPGADHALAIDRGSEWVVGLQ
SRNGGWGAFDADNTYHYLNNIPFADHGALLDPPTEDVTGRCIGMLAQLGEKPDSPRIKAA
VDYLARVQLKDGSWFGRWGVNYIYGTWSALAGLNAVQVDPRSDMMRRAVDWLVAIQNADG
GWGEDCDSYRLDYRGYQPAPSTASQTAWALLGLMAASEVDHPAVARGIAYLKATQEDDGL
WGQEHYTGGGFPRVFYLRYHGYPKFFPLWAVARYRNLKAGNSRRVAYGL
>A0A0A1VVU8|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa NIES-44|TrEMBL
MKINLVGCEFRTPFVFRGVGVLNQLSVISQKKKEIGNQSKFLDWIPWEQKPIFYLLIKNF
VNKIILFALVVPRGCRTEKMQIQDKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELES
NVTITSEAILLHKIWKTDKNRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGL
RLLGIPANDPALEKAREFILAKGGISKTRIFTKMHLALIGCYDWLGVPSIPAWIMLLPEN
FPFTIYEMSSWARGSTVPLLIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVF
LWLDGLFKWAEKTDLVPFRQESLKAAEKWVIERQEDPGDWGGIIPAMLNSLLALKALGYD
VYDPIVARGLKAVDNFAIQTDNTYCVQPCVSPVWDTAWVIRALIESGLNPAHPAMIKAGQ
WLIDQQILDYGDWAIKNKIGTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKG
VMKRAVNWMATMQCKAGGWGAFDIDNDQNWLNSLPYSDLKAMIDPNTADVTARVLEMLGT
CDVKMEENRVKKALDYLEKEQEADGSWFGRWGVNYIYGTSGALSAFAFLEPNKYRHQLQK
GANWLSSCQNVDGGWGETCFSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVI
EKGVNYLLVTQKENGTWDEDYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A521KW48|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
MQLIKSLITRLSNSLFASGPGRLRGGTSAGTAASIRLVSHNPHAAAVPDQTGRRVASPSM
GQSESVDEAVRRSQAWFLSRQHPREGYWVAELEADTTLTSEYLMLRRFLGKVDPERERKA
VRYLRTMQLPDGGWSIYYGGLCEISASVKAYFALKLSGVSADEPFMVRAKDAIRARGGVV
AANVFTKITLALFDQYDWRGVPSMPPEIMLLPKRFYFSVYALSYWSRAVLIPLLIVFLHR
PVCRIPREQGIDELFVQSREHVAFNKVPPFKKDDAWFTWRNFFITLDQGIKLYDRMPIRA
LRDAAVRKAAEWMLAHVKGSGGLGAIYPAMANSVVAMRCLGYGVDHPSVVKALREIEALE
VYDVARDGQGPAETLHLQPCFSPVWDTALLMNALVESGMPQHHPALQKAAAWLCSRQATA
VGDWKVSSPQAEPGGWYFQFENELYPDVDDSAVVLMALAKLRLSDRQTQQAIARGYRWVM
AMQGSDGGWGAYDKDNNRMVFNLIPFADHRALLDPSTADIAGRCLELLGTLGYDRTHPAA
GPALGFLLREQEADGSWFGRWGVNYIYGTWSVLAGLQAIGEDMSAPYIRRAVAWLESKQN
PDGGWGESCLSYAEPATAGQGESTPSQTAWALIALFSAGATDSISVVRGVNYLLRQQRED
GSWEEVRHTGTGFPRVFYLRYHWYAQYFPLWALALYRNMRAHGRSKADELCQAARETGCF
WSQV
>B8EQD7|squalene-hopene cyclase|EC 5.4.99.17|Methylocella silvestris (strain DSM 15510 / CIP 108128 / LMG 27833 / NCIMB 13906 / BL2)|TrEMBL
MDDRVGAATFEAQPRAGFGSVEAAISRAREALLAVQKPDGHFVFELEADVSIPAEYILFR
HFLGDPAKTEIERKIGVYLRRRQTAAGGWPLFAEGVFNVSSSVKAYFALKIIGDDPNAPH
MAKARNAILAHGGAAQSNVFTRSLLALYGEVPWRAVPAMPVEIMHLPRWFPFHLSKVSYW
GRTVIAPLIVVHALKPRAKNPRKISVSELFVAPAETVSRWPGAPHKSFPWTTIFGAIDRV
LHKTEPLLPARSHQTAIDKAVAFVTARLNGEDGLGAIYPAMAYSAMMFFALGAPLSDPRI
VQIRKAIDRLLVIKDGEAYCQPCVSPVWDTALASHALMESAGQRPEARTAPAAAAVFEAL
DWLKPLQVLDVKGDWATQNPDVRPGGWAFQYANPHYPDLDDTAVVVLAMDRAVKTSPLIA
GEEETAYVEAISRAREWILGLQSANGGFGAFDADNDRDYLNYIPFADHGALLDPPTADVT
ARCVSMLGQLGERPETSPALARAIDYLLSEQEEEGSWFGRWGMNYIYGTWSVLSAFNAVE
RPADCAATRKAAAWLKRIQNPDGGWGEDGESYALGYKGYNPAPSTASQTAWALLALMAAG
EVDAPEVALGLDYLVSTQADDGFWDEARFTATGFPRVFYLRYHGYAKFFPLWAMARYRNL
KSGNRLKTQFGM
>A0A3P0PA48|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp9017|TrEMBL
MNDLTDMANLSAGTTPAGLDAAVASATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELERKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKSVEKLLVVNEDEAYCQPCLSPVWDTSLAAHALLETGDARAEDAAMRGLDWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLRHTDTYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSDPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGIDYLI
ARQNDEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGI
>A0A522RWH0|squalene-hopene cyclase|EC 5.4.99.17|Rhodanobacteraceae bacterium|TrEMBL
MAPDSGIPQQASTARGASGPQDRLTAAIDAARARILACQHGDGYWQYELEADCTIPAEYI
LMLHYLGESDRLLEARLAEYLRNHQSRDGGWPLYPGGALDVSCSVKCYYALKLAGDRADA
AHMARARAAILAHGGAARSNVFTRIALALFGELPWHGVPFLPVEVVLLPRWFPFNLSKVS
YWSRTVMVPLSVLTTLKPRAANPRDVHIDELFVTPPEQEKHYFNPRSLLNRVLFLCEEAM
RHLEPLIPNRLRRRALKHAEAWILQRRNGEGGLGAIFPAMVNAYEALALMGYPAEHPARR
ETRKAIDDLLVVHDNEAWCQPCVSPVWDTGLACLALQEDPDAPATNIEQALDWLTSQQLC
DAPGDWRDYRPNLPGGGWAFQFKNDAYPDLDDTAAVARALRQSPRHAKFAKVIARAADWL
VGMQSKNGGFAAFDADNDHQWLNQIPFADHGALLDPPTSDVSGRVLMLLSMLDRETDRDA
RERVMRFLLDEQTPEGAWFGRWGTNYLYGTWSVLVALRAAGLSTQSPEIRRAVAWLKSVQ
QADGGWGEGNDSYLNPELRGRGARSGPAQTAWALLALMATGESDSPAVARGVEYLLRTQT
DGEWHSTRFNAPGFPRVFYLKYHGYSRYFPYWALVRYRNAQRRR
>A0A7C2UUH4|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Acetothermia bacterium|TrEMBL
MSWAAVKEKKEKGDPREYLIVDRPAPHTHGRDGVEDLEEALDRAVDWLLSRQSPEGWWWA
ELGSNVTITAEHLFLTHILGIGTQELWDKIARYILSEQRPEGFWANWYGGPGDLSTTVEA
YLALKMAGVDPNSPAMKKAREWILSQGGVEKTRVFTKMWLSMLGEWPWEATPMVPPELIL
LPDRFPVNLYSFASWARGSILPLAIVRVLKPVWPISPYARIDELFPRGRANADLSLPRKK
SIWGRFFYGVDKALRSYERRPIRSLRKIALERAEEWILVRQEADGCWGGIQPAWVYSLLA
LYALGYPLQSPVLARGIAGFERYGIEDERGFRLQSCISPVWDTGLAMCALQDAGLPSDHP
ALVRAGTWLLGEQIFVGGDWQVKCSARPGGWAFEFDNDVYPDTDDTAVVMMALLGTSLPE
ENKGFALRRGLEWLLGMQSRNGGWGAFDRDNTKAFLREIPFADFGELRDPPSADVTAHIV
ELLGRLGYRPGFRPLDRALRYLLREQEEDGSWYGRWGVNYLYGTGAVLPALAACGWEMAD
PRVRKAVQFLLARQNEDGGWGEDIASYGRVELRGRGPSTPSQTAWALLALLAGGEGQGEA
VQRGIAYLVRTQREDGTWDEPQFTGTGFPTDFMIRYGLYRHAFPLMALGRAREGR
>A0A3N8IAH4|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp8992|TrEMBL
MIRRMNKSAPSPWSALDTAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDDRQEKMARYLRANQRLDTHGAWALYVDGAPDVSCSVKAYFALKAAGDSEHAPHMIRA
RDAILKLGGAARANVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNISIRELFVTPPDEERQYFPPASGMRKVFLALDRTVRHIEPL
MPKRLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMQVLGYPDDHPLRRDCENAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVAAPEAGEAASGALRELDERIARA
YDWLAVRQVNDLRGDWIENVPADVEPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRTHRN
ADGTNPHAARVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVS
GRVLLCFGVTKRAEERASLARCIDYVKRTQQPDGSWWGRWGTNYIYGTWSVLAGLALAGE
DKSQPYIARAIDWLRARQHADGGWGETNDSYIDPKLGGTNGGESTSNFTAWALLAQMAFG
DHESDSVKRGIAYLQSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRL
AGAAAAAPAAVEATDTAVA
>A0A6M4WZN2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces asoensis|TrEMBL
MTATTDGSTGALPPRAAAASETDITIPVAAGVQEAATRAMQRATDFLLAGQDAEGWWKGD
LETNVTMDAEDLLLRQFLGIHDEATTRAAALFVRGEQREDGTWATFYGGPPDLSATVEAY
VALRLAGDAPEAPHMSRASGWIREQGGIAAARVFTRIWLALFGWWKWEDLPELPPELLFF
PKWFPLSIYNFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHADPANPNPAKPLAPVNSW
DGLFQRLDKVVRGYRSVAVRRLRKAALNSAARWIIERQENDGAWGGIQPPAVYSVIALHL
LGYDLQHPVMRAGLESLDRYAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQL
VKAADWMLGEQVVRPGDWSVSRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHHDP
ERMDRAIARGVRWNLGMQSKNGGWGAFDVDNTSPFPNRMPFCDFGEVIDPPSADVTAHVV
EMLAVEGLSHDPRTRRGIEWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALTAAGLPAQHP
AIRRAVGWLERVQNDDGGWGEDLRSYQDATRWSARGASTASQTAWALMALLAAGEKDSKA
VERGVAWLAQTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFSKQ
PATHAASTEAKGG
>A0A517IGP1|squalene-hopene cyclase|EC 5.4.99.17|Brevibacillus brevis|TrEMBL
MLFPLSSLGDVFYREVNELREVQQEINRIQAFLLQRQQEDGTWRFCLESSPMTDSHMIIL
LRTLGIHDERLMEKLTAHITSLQHDNGAWKLYPDEHEGHLSTTIDSYYALLLSGKYTKDE
PRMALARSFILEKGGLTQANMLTKFSTALTGQYQWPSHFLVPVEIALFPPSFPVSFYDFV
GYARVHLAPMMIVADRKYVKKPDNAPDLSDLYADTPISRGLYPHRFVENFLKEGQTFLAT
IHDSLQRLPFLPGQLHKLALRRLEQYILARIEPDGTLYNYSTSTFFMIFALLARGFSPKD
PLIQKAMQGLTNSIYDYENGAHLQLATSAVWDTALLTSSLQKSGLSTTHPAIQKANRYLL
QKQQHTYSDWKIRNPKGRPGGWGFSDYNTMNPDIDDTTAALRSLRLLARTDITTAAAWKR
GLEWLLSMQNDDGGWPAFERNTDADFIRHLPIEGADTVSTDPSSADLTGRTLEFLGNYAG
RTLTDPHVEKGVRWLLKHQESDGSWYGRWGITYLYGTWAAITGLMAVGFSPTDPTIQKAV
AWLVTNQNPDGGWGESCQSDQKKTYVPLGASTPSQTAWAIDALIAVSSKPTPELQRGIRY
LLTHNQANDWTTRYPTGGGRPGGTYFAYHSYRWIWPLLALSHYQTKYAST
>A0A846GFC8|squalene-hopene cyclase|EC 5.4.99.17|Okeania sp. SIO2B3|TrEMBL
MIEKNKVKQSILASQEYLLNLQKAEGYWWGKLESNVTITAEIVLLHKIWQTDNKRPLYQA
KLYLISQQREHGGWELFYGDGGDLSTSIEAYMALRLLGLSKTDPIMLKAREFIVKLGGIS
CSRIFTKLHLALIGCYNWQGIPSIPPGIMLFPEDFPFTIYEMSSWARSSTVPLLIVFDKK
PIFSLNPTINLDELYAEGINNATFELPRQYNLTDLFLGLDTAFKFLENLNLMPLREEGLK
AAEKWILERQEVTGDWGGIIPAMLNSMLALRCLEYDVADPVVVRGLEAIDRFGIKTEDSY
WVQPCVSPVWDTAWVIRSLVDSGIAASHPAVVKAGEWLLQQQILDYGDWAVKNKLGKPGG
WAFEFINRFYPDIDDTAVVVMALDAVELPDQELKRVAIARAMEWVASMQCEPGGWAAFDV
DNDQDWLNGIPYGDLKAMIDPNTADVTARVLEMVGCCGLSMNSRRVKRAIDYLEREQEGE
GCWFGRWGVNYIYGTSGVISALAVVARESHGGYIERGATWLVGCQNSDGGWGESCRSYND
PSLKGKGKSTASQTAWALIGLLAAGEATGNFARDTIDRGVDFLVSTQNDDGSWFESEFTG
TGFPCHFYIKYNFYQQYFPLMALGRYENLIKE
>A0A553M0J0|squalene-hopene cyclase|EC 5.4.99.17|Geobacillus sp. LEMMJ02|TrEMBL
MVADERSTLIAVLKRSQAADGSWRFPFETGISTDAYMIILLRTLEINDEPLIQALVKRIE
SRQGANGAWKLFADEGDGNVTATTEAYYALLYSGYRKKTDPHMQKAKMRILEMGGLENVH
LFTKVMLALTGQYPWPRRFPLPLAFFLLPPSFPLNMYDLSVYGRANMIPLLVAAERRYSR
KTAKSPDLCDLAASRGGWRLPENRALWSYIKRALIGFPAELHDAAKRRAVRYMFDHIEPD
GTLYSYFSSTFLFIFALLALGYPKDDPHIVRAVRGLRSLRTEIDGHTHMQYTTASVWNTA
LASYALQEAGVPPTDRTIEKANRYLLSRQHIRYGDWAVHNPYGVPGGWGFSDVNTMNPDV
DDTTAALRAIRRAADKETAFRHAWDRANRWLFSMQNNDGGFAAFEKNVGKRFWRYLPIEG
AEFLLMDPSTADLTGRTLEYFGTFAGLTKDHSAIARAVDWLLDHQKADGSWYGRWGICYV
YGTWAAVTGLSAVGVPIDHPAMQKAVRWLLSIQNDDGGWGESCKSDEAKTYVPLGASTPV
HTAWALDALVAAADRPTAEIKAGVRALVRMLHHPDWTASYPVGQGMAGAFYIHYHGYRYI
FPLLALAHYEQKFGPFVD
>A0A5P1ZYB6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces venezuelae|TrEMBL
MTATTDGSAGAVGPRAAAASTTNDTGAPDLDEAAARATARAVEHLLARQDPEGWWKGDLE
TNVTMDAEDLLLRQFLGIRDEDTTRAAALHIRRQQCEDGAWATFYGGPGELSATVEAYVA
LRLAGDPPDAPHMARASAWVRARGGIAAARVFTRIWLALFGWWRWEDLPELPPELLFLPK
WFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPERPNPPRPLAPATGWDG
LFQRLDKALHAYHRVAPRALRRTAMNLAARWIVERQENDGCWGGIQPPAVYSVIALHLLG
YDLKHPVMRAGLESLDRFAVWREDGSRMIEACQSPVWDTCLATIALADAGLAPDHPALVK
AVDWMLDEEITRTGDWAVRRPELPPGGWAFEFHNDTYPDIDDTAEVLLALRRVRHPDPAR
VDAAVARGMRWTLGMQSKGGAWAAFDADNTSPFPNKLPFCDFGEVIDPPSADVTAHVVEM
LAYEGLAQDPRARRGIDWLLAEQEPNGAWFGRWGVNHVYGTGSVLPALTAAGLPVSHPAV
RRAVGWLGSVQNDDGGWGEDLRSYKEEEWVGRGPSTASQTAWALIALLAAGERDSEPVRR
GIAWLAGTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGEPVPGKVG
>A0A4R5BHD9|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura rubrisoli|TrEMBL
MTTTEPAESIETPAAGRDAAAGRGAAAERGAAPSTADAAKAALEAARDHLLGLQSPEGWW
KGELQTNVTMDAEDLLLRQFLGVRTDEDTREAARWIRSQQAADGTWANFHGGPPELSTTV
EAYVALRLAGDPPDAGHMLRAAAHIRDAGGVPATRVFTRFWLAMFGLWPWDELPVVPPEL
MFLPPWFPLNVYDFGCWARQTIVPLTVVGALRPVRPLPFGLDELRAPGARVPGARAPGAK
PRRGLPGWDEAFGALDKALHVYERHVRDRRPARALRRAALRRAGEWIIARQEPDGSWGGI
QPPWVYSLLALNLLGYDLDHPVMRRGLAGLDRFTIRDGTGRRLEACQSPVWDTVLAMNAL
ADAGLPAGHPALERAAEWVIREEVKGPGDWSVRRPGLPPGGWAFEFDNDCYPDTDDTAEA
VLALGRVAHPQAGPAIERGLRWMAGMASRDGGFAAFDADNTRALCRKLPFCDFGEVIDPP
SADVTAHVVEALCAQGMADSTAVRRAVVWLLKAQEPDGSWFGRWGANHVYGTGSVVPALI
AAGVRPGKPAIRRAVSWLERHQRDDGGWGEDLRSYRDPAWIGRGVSTPSQTAWALLALLA
AGERGGTSPAVDRGVAWLTAHQRPDGTWDEDHFTGTGFPGDFYINYHLYRLVFPVSALGR
YLKESGSP
>A0A849UBR8|squalene-hopene cyclase|EC 5.4.99.17|Methylococcaceae bacterium|TrEMBL
MFNEAHTETNSIQHYSSGFSTLGASGINAAELNSAISKAQEKLLSFQDSAGYWVFELEAD
CTIPSEYILMMHYLDDINLPLQAKIANYLRSRQSEDGSYPFYTGGPGDISGSVKVYFALK
LAGDSIDAPHMVKLREFILSQGGAAKANVFTRIALAIFKQLPWRGVPYIPVEIMLLPKWF
PFHLDKVSYWSRTVMVPLFILCTLKATAKNPTNTNVLEIFVTHPDEEQHYFPERTLLNKI
FLGLDFLGRVTEPLIPEKARNLAIEKARDWFVERLNGEDGLGGIFPAMVAAYQSMLLIGF
SEDDDHVVTCRKAIDKLLVINEDDAYCQPCLSPVWDTALAALAIQEVDKTANTQSLTRAY
DWLKSVQLSDEPGDWRISKPDLAGGGWAFQFANPHYPDVDDTAVVAFAMAESNLPNLEES
IHRATRWIVGMQSKNGGYGAFDVDNTYYYLNEIPFADHGALLDPPSSDVSARCAMLMARV
AKNHPDYLPALERTISYLRTEQEADGSWFGRWGTNYIYGTWSSLMGLEQTPVPKSDPMYT
KAVAWLKSVQREDGGWGEDNYSYHDASFAGKYHFSTSFHTAWALLGLMAAGEANSPEVKA
GIEFILRKQQSNGVWDDPCFTAPGFPKVFYLKYHGYDKFFPLWALARYRNELNKS
>A0A4R5QAJ5|squalene-hopene cyclase|EC 5.4.99.17|Dankookia rubra|TrEMBL
MQDLAAVAARPDLSLAETLTEAHRSPLDAAIGRATGNLLRRQQADGHWVFELEADATIPA
EYVMLRRFFGRQDPAREARIGRYLRRVQAQEAARCGGGWPLFHRGPLDVSCSVKAYFALR
LIGDAEDAPHMLRARAAILAAGGAERCNVFTRATLALFGQVPWHAVPVMPPELTLLPRWF
PFHLSKVSYWARTVLVPLTVVMARRPPPVAPIRVSLRGLFRTPPEQVKRWPGGAHAAQPW
KGIFARLDRELQRTQHLFPASIRSRAEAKAEAFVTERLNGEDGLGAIYPAMANAIWMYHC
LGVAEDDPRLVTAWAAVEKLVMDRPDLDETYVQPCLSPIWDTALVSHALLETGEPAAEAA
VTRGLSWLLERQITDVAGDWAEARPGVAPGGWAFQYANPHYPDVDDTAVVVLALDRAEKQ
LGGSGSAVARSISLATDWVLGMQSKGGGWGAFDADNTHHHLNSIPFADHGALLDPPTSDV
SGRCLAMLAQLGHGADNPAVRQAIDYMLAEQEPDGSWYGRWGVNYVYGTWSAVTALNAAG
LPPEHPAMRKAVTWLKRCQNPDGGWGEDGFTYPRRGGTRADADMAMGPSTASQTAWALLA
LMAAGAVEDPAVGRGAAWLLARQAGDGSWPEEDYTGTGFPRVFYLRYHGYAQLFPLWALA
RLRRLRLGNSRHVPHGL
>A0A7Y0K5A9|squalene-hopene cyclase|EC 5.4.99.17|Niallia alba|TrEMBL
MNTFLESVKTEQQRRVKELVEHQQANGSFPFRFQGSLMTDAFYIITIRALDIQTEEENIR
LLTKTLRATQHREGYWKAYSDEPNGHLSATIIAYTALLYSGHYSKNDNQMKKAKAFIVKN
GGLAKAHFMIKWMLSVNGLYPWSHMIYIPMTFLLLPTFQPINFYQFSAYARIHFIPMLIA
ANKKFTIDAKTKPQLDDLFARDIALYPSYAHLEDERSPITFLWKEMKRIGKFPSYLHHLG
FQYGEKYMLDRLEEDGTLYSYASATFFMIYALLALGYKKDSPVIQKAVTGLSSLIDKRGE
QSHLENSTSTVWDTGLISYTLQQAGMATDTTPIRKATKYLLTKQHTKKGDWQVHNPHTEP
GGWGFSDINTNNPDNDDTSAVLRAITAPAAIDQTVHQAWQKGTNYLLSMQNRDGGWGAFE
KNTDWEILKLVPIENAKDAAIDPSTADLTGRVLEYLGNFAHLDYTHPHIKRAKSWLIDHQ
EKDGSWYGRWGVCYIYGTWAAITGLAAVGMDVNHPTIKKAIAWLKKIQQSDGGWGESCQS
CEKLSYVSLPFSTESQTAWAVDALVAAGEGASKEVKRGISYILEKKQEDDAITYPTGIGL
PNQFYIYYHSYNKIFPLLALSHYISDRKTR
>A0A7W7SHL8|squalene-hopene cyclase|EC 5.4.99.17|Kitasatospora gansuensis|TrEMBL
MTATADGRLDPEYDPEPAAVGERPPVPERLNGRQVTVAQAAAVPLGSRRWEPDGPTAVVP
SDDPTPAEALARATAELLSRQSPEGWWKGDLETNVTMDAEDLLLRQFLGIRTAEHTEATA
AWIRSQQREDGTWSTFYGGPAELSTTVEAYVALKLAGDDPNAPHMLAAARHVRAAGGIAA
SRVFTRIWLALFGWWPWERLPEMPPEIIFLPRWVPLNIYAFGCWARQTIVPLTVVSAHRP
VCPAPFDLDELHTDPANPYPLRPLPPLNGWDGVFERLDLALHAYHRHAVKPLRRVALAQA
GRWIVERQEADGCWGGIQPPAVYSLIALHLLGYELDHPVMKAGLAAFERFTVHTEDGARW
LEACQSPVWDTCLATIALRDAGLPADHPALVSAVDWMLAEEITRPGDWAVQRPRLAPGGW
AFEFENDNYPDIDDTAEVVLALQRVDHPDREKLTGAVERGVEWNLGMQSKNGAWGAFDVD
NTSTLPNKLPFCDFGEVVDPPSADVTAHVVEMLAETGRADDRRTRRGIDWLLKNQEADGS
WFGRWGTNYIYGTGSVLPALVAAGLPTGHPAIRRAVSWLEDRQNPDGGWGEDMRSYEDPE
QWSGRGDSTASQTAWALMALLAAGEGPDGARGESVERGVQWLCHTQLPTGSWDEPQFTGT
GFPWDFSINYHLYRLVFPVTALGRYLHGSPLTGGRK
>A0A534E2H3|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MQPCAPALASGRLEWPVRRELATVTRGSPTRGSSAVAPNAARADAPAHKIHRLTEFSPLD
RSIAAARDALISLQSSQGYWLFELEADCTIPAEYVLMTHFLDEIDASLEPKLAAYLRARQ
AEHGGWPLYHGGDFDMSCSVKAYFALKLAGDSPQAPHMVRARAAILQRGGAARCNVFTRI
TLALFGQLPWRGVPYIPVEIVLLPRWFPFHLDKVSYWSRTVMVPLLILCTRQPAASNPRK
VQIRELFTTPPEEERHYFRRPGGRQGVLSRAFLALDRLGRMIDPLIPKALRAYATRRAEA
WMLERLNGEHGLGAIFPAMVNALEALAVLGYATSDAPRVAAKRALEKLLVVNASSAYCQP
CVSPVWDSALASLALQETGGAAALAASVRALDWLQPLQLLDNPGDWRVRRPQLAGGGWAF
QFWNAHYPDLDDTAVVAWSMHQAGDPARYAHNVQCALDWLVGMQSHNGGFASFDVDNTHY
YLNEIPFADHGALLDPPTSDVTARVVTVLARVGRPQDQAVLARAIAFLRQEQEADGSWFG
RWGTNYIYGTWSVLTAFAQAGIGPDDPATRRAVSWLTARQNADGGWGESNDTYAYGQLAA
GKSPSVPHQSAWALLGLLAAGEAGTDAVRRGVEYLLRTQQDDGLWSDPSFTAPGFPRVFY
LRYHGYCAYFPLWALAAYRTLIRLGTTH
>A0A8F9G3F9|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia edwinii|TrEMBL
MNDLSLAQPLGEANPAADRAEDATVAVDPGGQVAAQVANPVAGEPAGQVGADAAAQAAAP
AGVVADANPDAKPDAALDAAVTRATDAILAAQRDDGHWVYELEADATIPAEYILLVHYLG
ETANLELEQKIGRYLRRIQLPNGGWPLFTDGAMDVSATVKAYFALKMIGDAEDADHMRRA
REAVLSHGGAEAVNVFTRVLLALFGVISWRAVPVMPVEMMLLPQWFPFHLSKVSYWARTV
IVPLLVLAAKRPVARNPRGVRIDELFIGTPVNTGMLPRAQHQSAGWFRFFRSIDAVLRVT
GGLFPKKTRERGIQAALAFVDERLNGEDGLGAIFPAMANSVMMYDVLGYPADHPNRAIAR
RSVDKLLAIHEDEAYCQPCLSPVWDTSLAAHALLETGDARAVAAAARGLDWLVPLQVLDV
RGDWISRRPNVRPGGWAFQYANPHYPDVDDTAVVVAAMHRVALDAKTQAYDAAIARAREW
VVGMQSSDGGWGAFEPENTHYHLNSIPFSDHGALLDPPTADVSGRCLSMLAQMGDMPATS
DAARRAYDYLLKEQEADGSWYGRWGMNYIYGTWSVLGSLNAVGMPPEHPAMKRAAQWLIS
IQNTDGGWGEDGTSYKLEYRGYERATSTASQTAWAVLALIAAGEVGHPAVARGIEYLVRE
QRDHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRHMKQSGETRVKVGL
>A0A7Y5RF53|squalene-hopene cyclase|EC 5.4.99.17|Acidobacteriaceae bacterium|TrEMBL
MAIDASKSTASSQAGTQPRFGRMDLELDKVSSGIKRAVDWLFGQQHQDGYWCGELEADVM
LEADYIFVHTLLGTGDRAKMQRAVNEILRHQNADGGWSLYPGGPSNVNYGVKAYLALKLM
GWRADHPLMVKARESVLSLGGVVECNTFTKLYLCALGAYDYDAVPAIPPEIILFPNWFYF
NIYEISSWSRGILVPLSIIYAKKPFKKLAPEEEIDELFVGGRDRANLHLRWDKKRPVSWR
NFFLLCDRVAHWAERVHIRPLRSMAIKKAEKWMLERFEKSDGLGAIYPAMLNAIVALRCL
GYSMDDPVLIRAVDEFEKLGIDCPEGTEDYPTPTFRMQPCFPPVWDTAQAIYALGEAGVA
KDDPRMIKAADWILSKEVRHKGDWAEKVRNVEPGGWYFEFNNEFYPDVDDTGQVLLALKC
VENPRERYQYEVCERALNWIWAMQCKNGGWAAFDKDNTKTIFEQIPFADHNAMLDPPTVD
ITGRMLEMLALYGYNRSDKRVEKAVQFILSEQESDGSWFGRWGVNYLYGTFLVLRGLQSM
GMWSHEPCILQATEWVRMVQNSDGGWGESCGTYDDPLQRGIGPSTPSQTAWALLALLAGG
DVRSDSVAKGVRWLIDHQHEDGSWDELVPGRNGESYYTGTGFPRVFYLGYHLYKQYFPLL
ALTTYIKARETEVSGALE
>A0A5A9DV62|squalene-hopene cyclase|EC 5.4.99.17|Bacillus sp. CH30_1T|TrEMBL
MKKKIENTIHKMVSDLQHKQNADGSWSFCFENSVMTDAYMIILLRSLEMDDQELVGRLVN
RLWKVQTREGTWKLFEDEKEGNLSSTIEAYFALMYSGKVKDDDKRLVKAKHFIEKKGGVH
KAHSITKSMLAIHGQYDWKYLVPIPIEFLLIPKQFPLNFWDFSSYARAHLAPLLLLKDQR
FSLKTKNRPQVQHLSRGPYEVRYSERELKLFSKINEGLQSLISIPSHLHQQARQFAQQYM
LQRIESDGTYLSYFSSTFYMIYALLAVGYKKSDPIIVKAIQGLKEMACETKKGIHIQNSP
STIWDTALISHALQEAGVDARDHSIEKAVEYLGKKQHFRYGDWAMESRVKPGGWGFSESN
NIHPDVDDTTAALRSITYSAAENPLVRQSWDRGIEWVIGMQNRDGGWPAFEINKTKGILT
SFPMDGSEAAAIDPSTPDLTGRTLEFLGSRAGLTKDHPQVNRGIQWLKLMQKDEGSWYGR
WGVCYIYGTWAAITGMKATGVPSSDKHIQRAKAWLESIQHKDGGWGESCYSDQEKTYLPL
SFSTPSQTAWALESLICIEDKPTPAIDLGIMAILELMNGEADDSTKTYPTGVGLPGNFYI
HYHSYQWTWPLITLSRYREKYG
>A0A7X1SQR2|squalene-hopene cyclase|EC 5.4.99.17|Gluconobacter aidae|TrEMBL
MLIYSDILEKEDRVSETLSRQSVEPDEINHAIEGAQTALGGKQKSDGHWVYELEADATIP
AEYVLLEHYLDRIDPEKQAKIGVYLRRIQGDHGGWPLYHDGGFDLSASVKAYFALKAIGD
DINAPHMRIAREAILDHGGAARTNVFTRIQLALFGEVPWDATPVMPVELMLLSRKAFFSV
WNMSYWSRTVIAPLLVLNALRPRAINPRGVHVQELFVKPPSEVNDWIRGPYRSVWGRFFK
HLDSALRPVLPLIPRSMHKKALKAASDFIEPRLSRGGLGAIYPAMANVVMMYRAQGVPDS
DPRAKTAWDAIQDLLVDHGDEIYCQPCVSPVWDTGLSGLAMIEAASGPAGTKTAETLAAL
KKSAEWLREHQILNVKGDWAINAPDLRPGGWAFQYENDYYPDVDDTAVVAMLLHRVDPEN
SREAISRAREWIIGMQSTNGGWGAFDIDNDHELLNHIPFSDHGALLDPPTADVSARCISF
LAQLGDPDDRPVILKAIEYLRSEQESEGCWFGRWGTNYIYGTWSVLCALNIAGVPHDDPM
VLRAVNWLESVQRPDGGWGEDCATYEGGTAGTYKKSLPSQTAWAVLALMAVGRRDSEAVK
RGVAYLVSQQNEKGEWQEEAYNAVGFPKVFYLRYHGYKQFFPLTALARYRNLGVSNSGKV
EYGF
>D3D417|squalene-hopene cyclase|EC 5.4.99.17|Frankia sp. EUN1f|TrEMBL
MSVSRVSEAIGHHIPEQVVDASAAVRDQAERDVRDVRGGADRLAGTLRRATRHLLSLQDS
TGWWKFDLESNTTMDAEDLLLRDFLGIRTESVTAASAKFIRSRQLADGSWPQYFGGPGEL
SITVESYIALRLAGDELSAPHMERAAAWIRRNGGVPATRVFTRIWMALFGWWRWEDLPVL
PPEIMLLPDQAPLSIYSFGSWARQTIVPLTIVFALRPVRPAPFGLDELSVDDPDDAGSTT
SGGIARLRGRVPLGWKQFFRWVDAGLHRYHHHPIGPLRRHAMRTAERWIIARQEADGCFG
GIQPPAVYSIIALRLLGYDLAHPVLKAALEALDDYSVTLPDGARMIEASQSPVWDTALAV
NAIVEAGDVIGIEPDDPALLRAADWLLGQEIRDRSGDWQVNHPGLPGGGWAFEFENDTYP
DTDDTAEVLLALRHVRHPAPEKIESATDRTVTWLLGLQSRDGGWGAYDSDNTSTLVYKIP
FGDFGALTDPPSADVTAHVVEALVDAGLTEDPRTQRGVSWLLDHQESDGSWFGRWGVNHV
YGTGSVLPALAAAGLAPSHPAIGGGVAWLLSRQNSDGGWGEDLRSYSDPRWIGRGVSTAS
QTAWGMLGLLAGEQGPDVAVALARAADWLADQQRPDGNWDEDQFTGTGFPGDFYLNYNGY
RLIWPVLALGRYGHSLRTSPPPTAADPKPRPGH
>I4GI08|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa PCC 7941|TrEMBL
MQIQDKITEIAAKTAKAIKLSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKALDNFAIQ
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPSIIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKSVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYSDLKAMIDPNTADVTARVLEMLGTCDVKMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYQALI
>A0A7W7D3X3|squalene-hopene cyclase|EC 5.4.99.17|Sphaerisporangium siamense|TrEMBL
MTTVDVDLPASSAGLALGAACDHLIGLRSPQGWWKGELQTNVTMDAEDLLLREFLGIRGE
EDTAGAARWIRAEQRADGTWANFHGGPPEPSTTVEAYAALRLAGDPPEAPHMRAAAAYVL
RAGGIEATRVFTRVWLALFGQWRWEDLPALPPELVYLPPWFPFNVYDWGCWARQTIVPLT
IVRAHRPVRPLPFDLDELRTGRPVRREARTGWERAFAALDHVLRRYERAPLKGTRAAALR
RAAEWIVARQEPDGSWGGIQPPWVYSLIALNLSGYDVDHPVMRKGIQGLDRFTIRDGEKR
RLEACQSPVWDTALAVNALLDAGIPAEDPAIVQAADWLIGEEVKGPGDWAVRRPGLPPGG
WAFEFDNDGYPDTDDTAEVVLALRRTGRPGAREAVDRGVRWMAGMVSRDGGFAAFDADNT
RALITRLPFCDFGAVIDPPSADVTAHVVEALAHEGYGRTRLLRRAVVWLLKAQEADGSWF
GRWGANHVYGIGAVVPALVAAGVRPESACVRRAVAWLRDHQNEDGGWGEDLRSYADPAWI
GRGASTASQTAWALLALLAAGERSEVVDRGVRWLVETQRPDGTWDEPYFTGTGFPGDFYI
NYHLYRLVFPISALGRYLAARERESDLATHGGESYLAARESDGFLEAREEDGFLADREED
GFLAAHEGDGAP
>A0A2Z3J508|squalene-hopene cyclase|EC 5.4.99.17|Salinisphaera sp. LB1|TrEMBL
MQTDSGRRALAFQDEILPHVSRTFALTIPELPEALRVAVGNAYLLCRIADTIEDDAELDY
QSKAAWHAEFVRVVETGEGGADFGQRLAPLLAPATLDAERRLVAHTDDVLTVMHGLRPAQ
RAAVARCVRIMCDGMPEYERAASADGLPTLAHLDRYCYFVAGVVGEMLSAMFTDYEPAMG
EHDAELNRLAVSFGQGLQMTNILKDIWADHGRGVCWLPRDVFARHGFDLSELGKRGADEA
FAAGLYELIGLATGHLRNALEFTLRIPGHQKGMRRFCLWAIGLALLTLRKIQAHPYFTDG
AQVKVSRRSVQATVLTTNLAVADDDRLRHLFHMTAGDLPALTPKLADDPAAPINDIAELP
RRSPATATRPAGLDDAIEAAEQRLFADQNPDGHWRYECEADGTIPAEYILMMHFIGDVDT
ALQARVANFIRYKQAAHGGWPLYYGGDLDLSCSVKCYYALKLAGDDVDAPHMAHAREAIL
ARGGAGQVNVFTLIALAQFGQVPWRAVPFIPVEVMLMPEASPFHLSKVSYWSRTVMVPLF
ILTSLRTMARNPAGVNIRELFTIPPEQQRDFVPAQNALQRVFKGLDLVGRNFEPLIPKFV
RKQAIKKAENWIIERLNGTDGIGAIFPAMVNVYEALGELGYPADHPYRANTRQAIDDLVY
DHGDMANVQPCMSPVWDTGLASLALQEAAGTGDTPVVRAGLDWLAARQVLDGPGDWRRDH
PDLPGGGWPFQYANDYYPDLDDTAVIAWAMVNTGDGATYGRAITRATNWLVGMQSSNGGI
AAFDTDNNHEYLNEIPFADHGALLDPPTADVTARVITLAGLLQRPEDRPFIERAMAYLRR
EQEADGSWFGRWGTNYIYGTWSVLMALEALGEDMSQDWIQRAVAYLKGMQRTDGSWGEDN
GTYWDPPRGRSDVSTSFQTAWAMLGLMAAGERGSAALARGAAWLIDRQGADGAWHDPEHT
APGFPRVFYLKYHGYTRYFPLWALARYRNLHGDPASDAGTAGAD
>A0A523PKJ3|squalene-hopene cyclase|EC 5.4.99.17|Proteobacteria bacterium|TrEMBL
MLDQRPKPQPVPPAEPWPPADAVEDSLPSTESFDEKLRVAIAAARDELLSQQHADGFWCF
EFEADCTIPAEYILMLHFMDEIDEEVEAKIAVYLREHQDSDGGWPLYPGGDFDLSCTVKA
YYALKLAGDDPDAPHMQAAREAVLGQGGAARSNVFTRITLALFAQVPWRAVPFVPVELML
LPRWFPVHISKVSYWSRTVTIPLAILCSLKARARNPKGVGIRELFTVPPEKEKHYFSIRS
GLDHAVFVSDRVGYLFESYIPRWLRRRAIKKAESWFIERLNGIDGLGAIFPAMVNAHEAL
ALLGYPADHLYRITTKAALKKLLVFRETSAYCQPCVSPVWDTGLACLTLHEVNGGQPTPE
TLCALDWLKERQLLDYPGDWSEYRPELRPGGWPFQFGNAHYPDLDDTAVVAWAMHQTRDE
RYRESISRAAEWLRGMQSKNGGFGSFDADSTYYYLNLVPFADHGALLDPPTSDVSARCLT
LFVQLDDPAHESAQRRSLEYLRLEQEKAGSWFGRWGTNHIYGTWSVLVALEQVGESKMAP
EIRRAAAWLKWVQRPDGGWGESNDSYLDPAMIGQSETSTAFQTAWAILGLMAAGETDSAA
VQRGAEYLLKTQQPGGSWKDEAFTCPGFPRVFYLKYHGYEKYFPLWALARYYNSRKRKAR
>A0A498DP27|squalene-hopene cyclase|EC 5.4.99.17|Oceanobacillus piezotolerans|TrEMBL
MNSRIKDEINRIVEVLRNDQSPDGSWDYPFESGLSTDAYMIILLRTLEINDEKLIQDLVE
RILSRQEKNGAWKLFDDEKNGNITATVEAYYALLYSGYRHEGDKEMAAARRRILAWGGIE
KSHMFAKIMLALTGQYKWPTFFPIPVEFILLPLSFPINFFDFPVYGRAHIAPMLILADQK
FAMKTKRSPDLSNLFLSRENDEFFLNPSGESRSFHTFIQQGIKNNIGLPASIHTMAIQQT
KKYIFDRIEPDGTFYNFFSSTFLMIFALLALKFPKNDRIITKAIDGLKGMATQIDGHTHM
QFTTANVWNTSLINDSLQRAGIPWNDPMIQQANHYLLSRQHSRYGDWMIHNPAPNPGGWG
FSDLNTMNPDIDDTTASLRSITHLVRNETVYRQAWDRGINWIFSMQNQDGGWGAFEKNVD
KKIVKLIPIKRIQYILTDPSTADLTGRTLEFYGNYTNLSNKHIAIKNGVNWLKSNQEKNG
SWYGRWGICYIYGTWAAITGMISTGVDTEHAYIKKSLKWLRDIQNPDGGWGESCYSDINQ
TYTPLGVSTLTQTAWALDTLIAASDKVTPEIQAGVTFLLDNADIKDWTFSYPKGQGLPGA
LYFHYHSYRYIFPLLALSHYKNKFLV
>G8ARS8|squalene-hopene cyclase|EC 5.4.99.17|Azospirillum baldaniorum|TrEMBL
MQDHNASTTLRVQRAEPSAKTVSDAVAEATDALIRRQQADGHWVFELEADATIPSEYLLL
HHILDEIDPELEAGLAAFIRGRQGKDGGWPLFFGGAMDISCSVKAYFALKAAGDSPDAPH
MRRAREAILARGGAARCNVFTRILLAQFGQIPWRAVPAMPVEVMNLPPWSPFHISRISYW
SRTVVVPLLVVMAHRLRARNPRGIGIAELFTEPPERVRNWHSNNSRGGWATLFRALDAAL
HAVEPRLPANGRQTAIDRAVRFVTERLNGEDGLGAIFPAMVNAVLMFHCLGMPPDHPDAA
TARRALRGLVVRQPGRVYCQPCLSPVWDTAIICNALLETGNPQARAAARRGADWLVDRQI
LDVEGDWAWQRPGLASGGWAFQYNNAHYPDTDDTAMVVMALQRLDTERYGEPIRRARDWI
VGMQSRNGGWGAFDAENQHDFLNHIPFADHGALLDPPTSDVTARCVMMLARLGEGRDTVP
TRRGLTFLEREQESDGSWFGRWGTNYVYGTWSALEALNAAGVPHSAVAVQRAAQWLLAHQ
RPDGGWGEDGASYWAGNPRGEGAVSTASQTAWALLGLMAAGKGNHPAVDRGVDYLLSARD
AEGLWSEEPFTAVGFPRVFYLKYHGYAASFPLWALARYRALRV
>A0A7W3WPZ8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces alkaliterrae|TrEMBL
MTTDATSPAASVERALDLAVGALRRGQDPTGYWKGDFESSLIGESGEVILRHFLGLPRDE
VTAEAAKTILAEQSATGGWASYHKGPDELLLSVFCYVALRLAGHEADEPAMRAAAASIRE
AGGIEAVDNPTMLAWLSVIGVWPWYDIPIIPPEVILLPSWFPGNIYQVGAAARGIVVANS
LFMAERPVTPAGFHITELFKRPDRGFRRLPRPRALRIATRLSHWYNRNPIGFLRRRAVRK
AADWLVRTQETDGSWGGNWPQTANVVMGLDTVGYRQDHPVIRKAMAALDGYVVHKNGQRR
IEMWTSVVMDTALGVSAAAMSGDPKARESADNAARWLLDTQVTELGDWAVLTKDPVAGGW
PYEFVNRTNPDADDTSFAVVALRRLHPRGTDATVDDAVDRACRWMLSQQCDDGGWAAFEP
LRWRLPGRDHLAKIGFLEAPSADITGHVLEALGADGQGEGEAARRGVEWLRRNQHEDGSW
PGWWACYHLHGTSAAVTGLTACGVPGTDPVVARACDWIEAHQQADGGWGEDIRALRDPAW
IGKGESTPSQTGWALIALIAAGRADSDAVRAGLDHLIRTQEADGDWPEPWHTWVVHHDGL
YWRDSMLRLIYPIMAMAAYRDHAAASGTTDATGEAR
>A0A6G2QEH2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID685|TrEMBL
MTATTDGSTGATLPSRAAAASDTTLTTPEAAGAPEAAAQAARRATDFLLSRQDAEGWWKG
DLETNVTMDAEDLLLRQFLGIQDERTTQAAAKFIRGEQREDGTWATFWGGPGELSTTIEA
YVALRLAGDAPDAPHMARAAAWIRERGGIAAARVFTRIWLALFGWWKWEDLPEMPPELIW
FPGWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPANPNPPKPLAPANT
WDGAFQRLDRALRQLRKVVPRRLRKAAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVLREGLASLDRFAVWREDGARMIEACQSPVWDTCLAAIALVDAGLPVDHPQ
LVKAADWLLGEEIVRPGDWAVKRPQLPPGGWAFEFHNDNYPDIDDTAEVSLALRRIRHHD
PERTDRAIGRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAAEGLAHDPRTRRGITWLLAEQEENGAWFGRWGVNYIYGTGSVVPALTAAGLPASH
PAIRRAVTWLESVQNDDGGWGEDLRSYKHVREWAGRGASTPSQTAWALMALLAAGEKDSK
AVERGIQWLATTQREDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFER
QLLARTPRPRPEAAKPAGSPLSEAKGS
>A0A369UZ94|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces parvulus|TrEMBL
MTATTDGSTGAALKPLAPSASEEDITVPAVAAGVPEAAARAVRRATDFLLSRQDAQGWWK
GDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFVRGEQREDGTWATFYGGPGDLSATIE
AYVALRLAGDSPDAPHMARAAEWIRARGGIAASRVFTRIWLALFGWWKWDDLPELPPELI
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAMPSPPRPLAPAA
SWDGAFQRIDRALHAYRKVAPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHP
QLVKAADWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVSHH
DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAH
VVESLAVEGLADDPRTRRGIQWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALTAAGLPTS
HPAVRRAVTWLESVQNDDGGWGEDLRSYRHTKEWSGRGASTASQTAWALMALLAAGERES
GAVERGVAWLASTQLADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFA
EKKRPAPKAERPAGAPATAEVEAG
>A0A370K4C5|squalene-hopene cyclase|EC 5.4.99.17|Dyella solisilvae|TrEMBL
MDAARRDAPHPQPAADRLDRAIERARLALMARQREDGHWCFEFETDCTISAEYILMMHFL
DEIDEVLQEKLARYIRLKQCLDTHGAWPLYHGGAMDVSCSVKAYYALKAAGDAADAPHMQ
RARDAILAMGGAARSNVFTRILLAMFQQVPWRAAPYVPVEIMLFPRWAPFHLDKVSYWAR
TTMVPLFVLCSLKATAKNPRRVDVRELFVTPPEQERHYFSSHGLISRLFLVLDKIGRACD
PWIPAAVRRKAVQRAEQWFLPRLNGEDGLGAIFPPMVNALEAMELLGYAKDHPARATCLK
SLQKLIVHRDDGTAYCQPCVSPLWDTGWAAMALLRASPDDATQAAVQRAMDWLTPLQELE
HKGDWAVQAPRLAPGGWAFQYANAYYPDLDDTAVIAALLHVTSRGTPRAEALRERIARAA
DWLVGMQSSNGGFAAFDRDNTHDLINQIPFADHGAMLDPPTEDVSGRVLACLGVLARPQD
QEAIHRCVAYLRKAQQPDGAFWGRWGTNYIYGTWSVLGGLALVGEDMQQPWIRKSVQWLL
SCQHADGGWGETNDSYYDPSLRGANGGVSTAHSTAWALLGLIAAGEHDAEAVWRGVQWLL
DDQQADGEREAALWYHPSFNAPGFPRVFFLKYHGYTAYFPLWALTRYRQLRDVPRSRATQ
>B4EM09|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610)|TrEMBL
MNDLTEMATLSAGAVPAGVDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANSVMMYAALGYAEDHPNRAI
ARKSVEKLLVVHDDEAYCQPCLSPVWDTSLAAHALLETGDARAQEAVLRGLEWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLTQSDTYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGYEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLV
AQQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A6G3RM78|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID339|TrEMBL
MTATTDGSTGAATPRAASASQSTETVLPIDTTAAGPREAAARAMRRSTDFLLARQDAEGW
WKGDLETNVTMDAEDLLLRQFLGIRDEDTTRAAALFIRGEQRDDGTWATFYGGPGELSTT
IEAYVALRLAGDRPDEPHMAKASAWIRDRGGIAEARVFTRIWLALFGWWKWDDLPELPPE
LIYFPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDARVPNPSKPLAC
VASWDGVFQRLDKALHVYHKVAPRPLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVI
ALHLLGYDLEHPVLKAGLASLDRFAVWREDGSRMIEACQSPVWDTCLATIALADAGVPAD
HPQLVKAADWMLGEQIVRPGDWSVRRPGLTPGGWAFEFHNDNYPDIDDTAEVALALRRVA
HPDKARLENAIDRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVT
GHVVEMLAVEGKSHDPRTRRGIEWLLAEQEENGAWFGRWGVNYIYGTGSVVPALITAGLP
ASHPAIRRAVRWVESVQNDDGGWGEDLRSYRDRGWVGHGTSSASQTAWALLALLSAGERE
AKSTERGIAWLVDAQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYINGEPF
AGGSDARTAKGS
>A0A7Z9PU89|squalene-hopene cyclase|EC 5.4.99.17|Phycisphaerales bacterium|TrEMBL
MANPSAPTDTVLAQALESIESAIAWTKKAQKPEGYWAARLESNASMEAEWLLAYHLLGVS
YDPKREGVIKCLLNTQREDGSWGVYQGSEAGDLNATVEAYAALRVHGKGPDEEFMTRARE
YILAHGGVAGTRVFTKIWLAMCGEWPWDGTPALPPEIIHFPLWFPFNLYNFASWARATIV
PLAVISARRPVVPFPPEARLDELFPSGRQKANTRLPYPTGGKPIQKFLYLADRVLTAYQK
MGWNPGRENSVKLCLEWILRRQEADGCWAGIQPPWIYALMALRFEGYALDHPVLEKGWRC
FDEPWAVEEPQGIFLQACTSPVWDTVLTQLALLDCGRGPGEDFYDRSLEWVLGQQIRSVG
DWKMKCPELEPGGWAFEYENDYYPDIDDAAVAMIVLARSRCYDDVKNEKIEQALERAAQW
VLGMRCSNGAWAAFDKDNNEELISLIPFSDFGESLDPPSVDVTAHVVEALGYLGRDLSDP
VVSRAVQYIQSEQENEGSWFGRWGVNHIYGTGAVLPALEKVGENMQADYIIKACDWLVEH
QNEDGGWGETCASYMDDSLRGRGESTASQTAWALMGLVAQGAKLERYRAAIARGVNFLHR
TQTAEGTWDEEAFTGTGFPGYGQGAKTDLKAGQTLPQGRELSRGFMLRYHMYRHYFPLMA
LGRAKALWAES
>A0A0H3G0J1|squalene-hopene cyclase|EC 5.4.99.17|Zymomonas mobilis subsp. mobilis (strain ATCC 10988 / DSM 424 / LMG 404 / NCIMB 8938 / NRRL B-806 / ZM1)|TrEMBL
MTVSTSSAFHHSSLSDDVEPIIQKATRALLEKQHQDGHWVFELEADATIPAEYILLKHYL
GEPEDLEIEAKIGRYLRRIQGEHGGWSLFYGGDLDLSATVKAYFALKMIGDSPDAPHMLR
ARNEILARGGAMRANVFTRIQLALFGAMSWEHVPQMPVELMLMPEWFPVHINKMAYWART
VLVPLLVLQALKPVARNRRGILVDELFVPDVLPTLQESGDPIWRRFFSALDKVLHKVEPY
WPKNMRAKAIHSCVHFVTERLNGEDGLGAIYPAIANSVMMYDALGYPENHPERAIARRAV
EKLMVLDGTEDQGDKEVYCQPCLSPIWDTALVAHAMLEVGGDEAEKSAISALSWLKPQQI
LDVKGDWAWRRPDLRPGGWAFQYRNDYYPDVDDTAVVTMAMDRAAKLSDLHDDFEESKAR
AMEWTIGMQSDNGGWGAFDANNSYTYLNNIPFADHGALLDPPTVDVSARCVSMMAQAGIS
ITDPKMKAAVDYLLKEQEEDGSWFGRWGVNYIYGTWSALCALNVAALPHDHLAIQKAVAW
LKNIQNEDGGWGENCDSYALDYSGYEPMDSTASQTAWALLGLMAVGEANSEAVTKGINWL
AQNQDEEGLWKEDYYSGGGFPRVFYLRYHGYSKYFPLWALARYRNLKKANQPIVHYGM
>A0A551Z3Q5|squalene-hopene cyclase|EC 5.4.99.17|Microcystis sp. M_QC_C_20170808_M9Col|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
KRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPANDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKAVDNFAIE
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKAVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRHQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A8J4M4Y0|squalene-hopene cyclase|EC 5.4.99.17|Acidicaldus sp|TrEMBL
MPHDNALFDLLPDDHLDAAIAAAGRALARTQRPDGHFVYELEADATIPAEYVLLEHYLDR
IEPELERKIGNYLRETQGTHGGWPLFHDGKLDLSASVKAYFALKAIGDDPEAPHMRRARA
AILAAGGAERTNVFTRILLALFGEVPWRAVPVMPVELMIAPRWFPINLWRVSYWSRTVMV
PLLVLMAKKPRARNPRGITIAELFRTPPGEIRDWIRGPYRSNWGRFFKGLDTVLRVLDPL
VPARVRAVSLRRAVAFVRARLNGEDGLGAIYPAMANSVMMFDVLGYQPDHPEAAIAWAAV
RKLLVIENDRAYCQPCVSPVWDTALAGHAIAEAEGNAAPPVAAACAWLGPLQITDVVGDW
AAARPAVAPGGWAFQYANPYYPDVDDTAVVGMLLHRTGDPAFAPAIARARAWIIGLQCRG
GGWGAFDADNDHQFLNHIPFADHGALLDPPTADVTARCVSFLAQIGMAADDPVLARAVAW
LRAEQERDGSWFGRWGTNYIYGTWSVLCALNAIGLAHDDPAISRAVAFLRATQRDDGGWG
EDAETYAGAPPGRYKESTPSHTAWAVLGLMAAGEVADPAVARGIRWLAEAAGRDGEWQEK
PYNAVGFPRVFYLRYHGYKQYFPLLALARFRALRRGNTRRVAFGF
>A0A4P8IYC7|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. DHOD12|TrEMBL
MNDLTTVPANDAATDAAVTEAAPSPAPQAGGAAARAQANPVLDAAVTRAVDALLAAQRPD
GHWLYELEADATIPAEYILLVHYLGETPNIELEQKIARYLRRIQLADGGWPLFTDGKLDI
SATVKAYFALKMAGDSEDAEHMQRARQAILANGGAEAVNVFTRILLALFGVIPWHAVPMM
PVEIMLLPMWFPFHLSKVSYWARTVIVPLLVLNAKRPKAKNPRGVRIDEIFKGAPVSTGL
LPRAEHQSQGWFVFFRGVDAILRATDGLFPRHTRQKAIDAAVAFVDERLNGEDGLGAIFP
AMANAVMMYDVLGYPPDHPNRAIARQSVEKLLVIGEEEAYCQPCLSPVWDTSLAAHALLE
TEEPRAEQAALQGLQWLRPLQILNVRGDWISRRPNVRPGGWAFQYANPHYPDVDDTAVVV
MAMDRAATLTQSNVDREAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALL
DPPTADVSARCLSMLAQLGEMPGTSEPARRAYDYLLKEQEADGSWYGRWGMNYIYGTWTT
LCALNAAGMPHDDPRIKRAAQWLISIQNEDGGWGEDGTSYKLNYRGYEKASSTSSQTAWA
LIGLMAAGEVDHPAVERGVAYLTKTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLW
ALARYRNLKRDASTRVTVGM
>A0A4R1CY83|squalene-hopene cyclase|EC 5.4.99.17|Frankia sp. BMG5.11|TrEMBL
MNDMRGPDMNVSDTVSVTRESIPTQTSAGDATARDRTAAAGSELAHALRLATDHLLALQD
GTGWWKFDLETNTSMDAEDLLLREYLGIRTAEVTAASARFIRSRQSDDGSWPQYFGGPGE
LSTTVESYIALRLAGDDASAPHMLSAATWVRDHGGVPATRVFTRIWLALFGWWRWEDLPV
LPPEIMLLPRRAPLNIYSFGSWARQTLVSLTVVSALRPVRPAPFDLDELYPDGPASAGSS
AGPGGGGSGAGASGVLERISTRFTAKEIFLGIDRLLHVYHRRPVRSMRNHALRAAERWII
ARQEADGCFGGIQPPAVYSIIALRLLGYELDHPVLKAALRALDDYSVTLADGSRMVEASQ
SPVWDTALAVNALADAGATAAIAPDHPALVRAADWLLGQEVRHRRGDWAVNHPDVPASGW
AFEFENDTYPDTDDTAEVLLALRRVRHPARDELDAAERRAVAWLFGLQSSDGGWGAYDAD
NTSTIPYQIPFADFGALTDPPSADVTAHVVELLAEAGLGGDDRTRRGVDWLLDHQEADGS
WFGRWGVNYVYGTGSVMPALRAAGVEPSHPAMRAGADWLLTHQNADGGWGEDLRSYTDPE
WSGRGESTASQTAWAMLALLTVGDQPEVSGALARGARWLADHQRPDGSWDEDQFTGTGFP
GDFYINYHGYRLLWPIMALGRYLRG
>A0A857DA19|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa FD4|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSDGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDLALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LTVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTNLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKAVDNFAIQ
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKGVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVKMEENRVKKAFDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSGCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A7W6TTG8|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. CIR48|TrEMBL
MQSAILESSVASATQGVLDFQQADGHWVFELEADCTIPAEYVLLRHYLAEPVDAVLEAKI
ANYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDPVDAPHMVRAREAIHARGGAI
HSNVFTRFLLAMFGVVTWRAVPVLPIEIVLLPFWSPFHLNKISYWARTTMVPLMVLAALK
PLAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFVLFRSLDAVLRVIEPMFPKALRKR
AIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKDENFPPRAITRRGIDKLLVIKD
DEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLDWLIPKQELELKGDWAVKRPDV
RPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGATGYDAAIDRGREWIEGMQSDDGGW
AAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETEKTSKHVADGVAYLR
KTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDHGDPMIRKAADWLASIQNKDGGWGED
AVSYRLDYRGWEAAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIATQNKKGLWDEQR
YTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A0F6L3K9|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia pseudomallei MSHR4000|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGAVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A6G2SA06|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID7815|TrEMBL
MTATTDGSTGAANLRAAAASDPTESTSAAPDMMAVARHAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETVKAAARFIRGEQLGDGTWNTFYEGPPDLSATVEAY
VALRLAGDRPDDPHMIRAAGWVREQGGIAESRVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPACPNPSRPTAPAASW
DGVFQRLDKALHLYHKVAPRRLRRIAMNEAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVSPDHPAL
VRAADWMLGEEIVRPGDWAVRKPGLAPGGWAFEFHNVNYPDIDDTAEVALALRRVRHPDP
ARVDAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGRAHDPRTRRGVEWLLAEQEASGAWFGRWGVNYIYGTGSVVPALIAAGLPAAHP
SVRRAVDWLRSVQNDDGGWGEDLRSYREEKWIGHGSSTASQTGWALLALLAAGERETRSV
ERGVAWLAATQQADGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFATAT
AIGAGTGKGA
>A0A1K0IGT5|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus necator|TrEMBL
MSMNETAFATAVPRIAPASAGDSPSPRGTAQALDHGIGRAIDALLHQQRPDGHWVYELEA
DATIPAEYVLMVHYLGEAPDLELEARLARYLRRTQNPDGGWPLFHEGRSDVSASVKAYFA
LKMAGDDPQAAHMQRARRAVQALGGAEASNVFTRTLLALYGVMPWSAVPMMPVEIMLLPQ
WFPFHLSKVSYWARTVIVPLLVLNSLRPQARNPRGVGINELFVGNCHTVGLPPRAAHQHA
GWYTVFRGLDALLRVAEPLVPRTLRRRAIAAAQAFVHERLNGEDGLGAIFPAMANSVMMF
DVLGVPPDDPARALARQSVERLLVEHGDEAYCQPCLSPVWDTALAAHALLETGEARATAA
AGRGLDWLRPLQVLDVRGDWTVRRPLVRPGGWAFQYANAYYPDVDDTAVVAAAMDRYMRA
HDMLGRYDEAVARAAEWIVGMQGGDGGWGAFEPENTHLYLNNIPFADHGALLDPPTADVS
ARCLSMLCQIGATPVKSEPAARALRYLLAEQMPDGSWFGRWGTNYIYGTWSALCALNAAG
LAPEAPEMRRAVAWLEQIQNADGGWGEDGSSYRLDYRGYEPAPSVASQTAWALLALMAAG
AAQHAAVARGIDYLLRTQQSGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWALARYRNL
QRGGAHRVSWGL
>A0A850ED53|squalene-hopene cyclase|EC 5.4.99.17|Tardiphaga robiniae|TrEMBL
MHSVSPEITIQNAALETSIASAKQGLLKFRQPDGHWVFELEADGTIPSEYVLLRHYLGEP
VDAELEGKIANYLRRTQGKHGGWALVQDGDFDMSASVKVYFALKMIGDSIDAPHMVRARE
AIRSRGGAVNVNVFTRFLLAMFGILSWRATPVLPVEIMLLPMWFPFHLNKMSYWARTTIV
PLMVLAALKPRAQNKKGVGIDELFLEDPSRIGGIKRAPHQSRAMFAFFTGIDILLRAAEP
YFPKKLRAHSIAKAVEFCEERLNGEDGLGAIYPPMANMVMMYEVLGFPADYPPRAIQRRG
IDKLLIVGEVEAYCQPCVSPVWDTALTAHAMLETGGDEAFGPAKEGLDWLATKQVLDVKG
DWAVKRPDLRPGGWAFQYNNAYYPDLDDTAVVMMAMDRARRQTGGKEYDVALDRGREWIL
GMQSSDGGFAAFEVDNLEYYLNNIPFSDHGALLDPPTEDVTARCVSMLAQLGDTVETSKP
LADGVEYLRRTQLAEGSWYGRWGLNYIYGTWSVLCALNAVGIDHQDPAFRKAVAWLLSIQ
NEDGGWGEDAVSYRLDYKGFEAAPSTSSQTAWALLALMAAGEVDNPAVARGTRYLMDTQT
EKGLWDEARYTATGFPRVFYLRYHGYSKFFPLWALARFRNLKSTNSKTVGVGM
>A0A1W7MBT4|squalene-hopene cyclase|EC 5.4.99.17|Novosphingobium sp. MD-1|TrEMBL
MTDPLAAVDAAVDRAASALSGAQRADGHWVFELEADCTIPAEYVLLRHYLGEPVAEELEA
KIGRYLRRTQSDEHHGWGLFHKGAFDVSATVKAYYALKMIGDDPAAPHMVRAREAVHKAG
GAEAVNVFTRIQLALFDAGPWSVVPTMPPELILLPRWFPIHLSKMSYWARTVVVPLLVLC
AKKPVARNAKGIKVDELYTRRPIDRKTQAADPKWVWTKSFNALDKVLKVAEGRWPRTLHQ
RAIDTCAAWVTERLNGEDGLGAIYPAMANSVMMYDVLGYPEDHPARAIARQSVENLLVIH
EDEAYCQPCVSPVWDTALAAHAMLEAGGADNVARAEAALDWLKPRQVLDVEGDWAEERPG
VRPGGWAFQYNNAHYPDLDDTAVVVMAMDRAQVADRMPIDRGVEWTVGLQSRNGGWGAFD
ADNDYDYLNNLPFADHGALLDPPTADVSARCVSMLAQLGERLDSPRMAAAIAYLRKEQEP
EGSWFGRWGVNYIYGTWSVLCALNAAGLPADDPAVARAVGWLKAIQNPDGGWGEDCDSYA
LDRKGHVPAPSTASQTAWALLGLMAAGEADSEAVERGVDWLVANQEADGLWGQEYYTGGG
FPRVFYLRYHGYPKYFPLWAVARYRNLKRSNTRQVAFGM
>A0A849HI51|squalene-hopene cyclase|EC 5.4.99.17|Acidocella sp|TrEMBL
MNANLDTAIDRASASLRGEQRPDGHFLYELEADATIPAEYVLLEHYLDRITPGLQEKIGV
YLRRIQGEHTTNPGGWPLFHGGKFDLSASVKAYFALKAIGDSPEAAHMLRARAAILAHGG
AARANVFTRIQLALFGAVPWDASPVVPVELMLMPGWFPINMRKVSYWSRTVMTPLMVLAA
EKPLARNPRNIRIDELFTTPPAQVRDWIRGPYKSAWGPFFKHLDTVLRAAEPWFPKKYRA
RAINKAIAWTIERLNGEDGLGAIYPAMANAAMMFDHFGDREHFDTAFAAVQKLLVVKDDE
AYCQPCLSPVWDTGLAGHALLEAGAPGPAAAACDWLAPRQILDVAGDWADNTPGTRPGGW
AFQYNNAHYPDVDDTAVVAMLMHRTGEPRYAGAIARAREWIIGMQSTNGAWGAFDINNDR
QYLNHIPFADHGALLDPPTEDVTARCISFLAQLGHPEDQPAIARGV
>A0A3R9WS44|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. WAC06614|TrEMBL
MTATTDDGGTCGADAVSGPDAAARGPVARAAAEAAARARDHLLGRQDAEGWWKGVLETNV
TMDAEDLLLRQFLGIRDEATTHAAALFIRGEQREDGTWATFHGGPPDLSATVEAYVALRL
AGDAPDAPHMARASAWIRAHGGLAAARVFTRIWLALFGWWSWDRLPELPPELLFLPSWVP
LNIYDFGCWARQTIVPLTVVSAHRPVRPAPFALDELHTDARDPYPTKPLAPALSWEGAFQ
RMDKGLHLYRRFAPRGLRRAAMNSAARWIVERQENDGCWGGIQPPAVYSVIALHLLGYDL
EHPVMRAGLESLDRFAVWRADGARMIEACQSPVWDTCLAVIALADAGVPADHPALVRAAD
WMLGEEVVRRGDWAVRRPRLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDPVRVDA
AVARGVSWSLGMQSRNGAWGAFDADNTSPLPNLLPFCDFGEVIDPPSADVTAHMVEMLAG
EGRAGDPRTLRGIAWLLAEQEADGSWFGRWGTNYIYGTGSVVPALTAAGLSAAHPAVRRA
VAWLESVQNPDGGWGEDQRSYRDRAWAGKGESTASQTAWALLALLAAGERESEVVERGIG
FLAGTQLPDGSWEEPHFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPRLGPRPAPGP
ATATVPPAASGGRS
>A0A846C5L3|squalene-hopene cyclase|EC 5.4.99.17|Okeania sp. SIO2F4|TrEMBL
MTENNKVKLSISASQKYLLNLQETEGYWWSELESNVTITAEIVLLHKIWQTDNKRPFDKA
KNYLISQQEEHGGWELFYGDGGDLSTSIEAYMALRLLGVAKTDRIMVKAQDFIIQKGGIS
CSRIFTKLHLALIGCFNWQGIPSIPPSIMLLPEDFPFTIYEMSSWARSSTVPLLIVFDKK
PIFSVNPTINLDELYAEGINNATFELPRQYDLTDLFLGLDKAFKFVEDFNLMPLREEGLK
AAEKWILQRQEVTGDWGGIIPAMLNSMLALKCLGYDVADPVVVRGWEAIDRFGIETEDGY
WVQPCVSPVWDTAWVIRSLVDSGIAASHPAVVKAGEWLLQQQILDYGDWAVKNKLGKPGG
WAFEFINRFYPDIDDTAVVVMALDAVELPDEELKSQAIARAMEWVASMQCEPGGWAAFDV
DNNQEWLNGIPYGDLKAMIDPNTADVTARVLEMVGCCGLSMDSWRVKRAIDYLEKEQEGE
GCWFGRWGVNYIYGTSGVISALAVVARESHGGYIERGATWLVGCQNSDGGWGESCWSYND
PSLKGQGKSTASQTAWALIGLLAAGEVTGNFAREAIDRGVDFLVSTQKDDGSWAESEFTG
TGFPCHFYIKYNFYPQYFSLMALGKYENLLS
>A0A3M2C176|squalene-hopene cyclase|EC 5.4.99.17|Gemmatimonadetes bacterium|TrEMBL
MSRERHTLNSIRHRSENCMSVGRAADRGAPNSAPSAPTLVAGLDPAIERARERLLGLQHE
DGHWRDEIEGDAVLEAEYVLLLHFFGRAHEPRAEKLGEYLRRQQGPHGGWSLYHGGPPDV
SSSTKAYFVLKLLGDSPDAPHMVRARETIRSLGGVEATNTYTKIYLAIFGQYPWERCPAI
PPEMVLLPDGFHVSLNAMSSWSRGIFVPLSVIWALRPLRVVPDYAAIPELFVDGGRPRVE
VPDAPLGRAIQAAIYGVDRGIKTIERLGLTPLRRKALAAAERWIRERLEQSDGLGAIFPA
IVNAAMALRALGLHPEHPHVRGQLEALEGLEIDLGDAMKIQPCHSPVWDTANTLSVLLTS
GLDPSHEACERAARWLVDHEVRRVGDWRTGNPEGPVGGWYFEYANEFYPDCDDTAEVLSC
LARVRVRDRTLRERVAAARRRGLAWLLSMQNRDGGWAAFDRGCDLEVLTLVPFADHNAMI
DPSCEDITGRVLTMLSYEGWDVGDPVVQRAVRYLHATQQPDGSWFGRWGCNYIYGTWLAL
SGLSAIGVDMAAERYRRAADWLASCQNDDGGWGESLASYDDPALKGIGPSTATQTAWALL
GLVAAGRGESEAVRRGVAYLLDTQRDDGTWDDPHWTGTGFPRVFYLRYHMYDDYFPLLAL
ARCRDALGRAVEADRDERAAS
>A0A7K3PYV7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces diastaticus|TrEMBL
MTATTDGSTGASLRPLAASASDTDSTIPAAAAGVPEAAARATRRATDFLLAQQDAEGWWK
GDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDAPDAPHMARASEWIRSRGGIASSRVFTRIWLALFGWWKWEDLPELPPELI
YFPTWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPARPNPPRPLAPAA
SWDGAFQRIDKALHAYRRVAPRRLRKAAMNTAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPEDHP
QLVKAADWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHH
DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAVEGLTHDPRTQRGVQWLLDAQEADGSWFGRWGVNYVYGTGSVIPALTAAGLPTS
HPAIRRAVRWLESVQNEDGGWGEDLRSYRYVREWSGRGASTASQTGWALMALLAAGERES
TAVRRGVEWLAATQREDGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFA
KKTAGADRATSAAAEVKGA
>A0A833JGE2|squalene-hopene cyclase|EC 5.4.99.17|Komagataeibacter medellinensis|TrEMBL
MSHTISAACDWLIGQQKPDGHWVGPVASNASMEAEWCLALWFLGLEDHPLRPRLGRALLE
MQREDGSWGIYYGAGNGDINATVESYAALRSLGYGADEPTLARAAEWIASKGGLRNIRVF
TRYWLALIGEWPWEKTPNLPPEVIWFPNSFVFSIYNFAQWARATLVPLAILSARRPARPL
RPQDRLDALFPGGRANFDYELPRKEGRDLWASFFRTTDRGLHWLQSRVLKKNSVREAAIR
HMLEWIIRHQDADGGWGGIQPPWVYGLMALHGEDYQFHHPVMAKALSALNDPGWRHDRGD
ASWIQATNSPVWDTMLALMALHDADGETRFTPQMDKAMGWLLDRQVRVKGDWSIKLPDVE
PGGWAFEYANDRYPDTDDTAVALIALSSCRNRPEWQARGVEPAIKRGVNWLVAMQSESGG
WGAFDKDNNRSLLAKIPFCDFGEALDPPSVDVTAHVLEAFGLLGLPRDMPAIRRGLAYIR
AEQAAEGPWFGRWGVNYLYGTGAVLPALAAIGEDMTQPYIAKACDWLVGCQQENGGWGES
CASYMEISSIGRGPTTPSQTAWALMGLVAANRRQDHDAIVRGCRYLIDLQQPDGRWDEKE
FTGTGFPGYGVGQTIRLDDPALSKRLQQGAELSRAFMLRYDLYRQLFPIMALSRAARVLK
AAG
>A0A3M0XVB9|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MSFRDQEKFSDRKPEGEQRHPSASPDARAVAALNAAGLAARAGVEDDLDRLVDETRRALR
ALQREDGHWVFEFEADATIPAEYVLLRHFLGDIDDALEQRIARYLRTIQSEDGGWPLFYK
GEPDLSATVKAYFALKLVGDDPQAPHMRRAREIVLARGGGAQCNVFTRIALALYGQVPWR
AVPEMPVEIMLLPRWFPFHLSKVSYWSRTVIVPLLILMALKPRARNPRGVRIDELFLRSP
DAERYPMNATGDAIGAFFVGLDALLRAAERRFPRGARRRAIDKAVEFILPRLNGEDGLGG
IFPAMANAVMAFDALGWSRDDPAFVMARRAIDKLLIDRAPDVTYCQPCLSPVWDTCLAMH
AMLEAGEDPDGPALRKATDWLLEREIHETAGDWIWRRPGLRPGGWAFQYRNDYYPDVDDT
AVVVMALDRIGDPRCRPAIERATDWVLGMQSSNGGWGAFDAENEYYYLNHIPFADHGALL
DQPTVDVSARCLSMLAQLGYRRDHPAVRRGLEFLRREQEPDGSWYGRWGVNYVYGTWSAL
CAFNACGEDMTAPHIRKAVAWLKARQRPDGGWGEDCATYWPEHRTLARASTASQTAWALL
GLMAVGEVDSEAVRRGVRYLERSPREGAKWHEKWYTGIGFPRVFYLNYHGYSAYFPIWAL
ARYRNLRATGRRWVRTGM
>A0A6N7F7Y1|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MLNRLEASSGAQGASGDDLLDSTIEAVAGALVDRQAGDGHWVYELEADATIPAEYILLNH
YLATVDDGTERRIARYLRRTQAGHGGWPLFHDGDFDISATVKAYYALKLVGDAPDAPHMQ
RAREAVLARGGAARSNVFTRITLALFDQVPWRACPLIPAEVLLAPQRSPLNILEKVSYWS
RTVMVPLLVLQTLKPHARNPRGVDILELFITPPDKEKAWLSNPTGHWLGDLMLWADRIGR
YLVPFVPKSAKRRALDKAVAFIHERLNGEDGLGGIFPAMANALMAFDALDYPRDDPDVLT
ARKAVDKLLVFKDDMAYCQPCLSPVWDTGLAAHALLEAGFDGDSPEMARACKWLVDCQIL
DVAGDWRQNRGHVRPGGWAFQYRNDHYPDVDDTAVVVMALERAGDPAWRDSIGRGAEWVI
GMQGQRGGWGAFDADNEYYWLSHIPFADHGALLDPATADVSARCVSMLAQLGYDRSHPAL
ARGLDYLRCEQEEDGSWFGRWGTNYIYGTWSVLCAFNAAGEDMDAPFIRKAVDWLVSIQR
DDGGWGEDCATYLPGRRGEAKASTPSQTAWALLALMAAGEVDSESVRRGVEYLLHAPRDG
GRWAEEYYNAVGFPRVFYLRYYGYAAYFPLWALARYRNLKNGNRRRPVFGM
>A0A537TR96|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MNCVQPKSSAVDQSIEAATRGLFALQQPDGHWVFELEADATIPAEYILLRQYLAEPVDNV
LEAKIAAYLRRVQGEHGGWPLFHEGAFDMSASVKAYFALKMIGDSVDAPHMARARAAIRA
RGGASRSNVFTRVMLALFGFIGWRAVPVMPVEIMLLPKWFPFHLEKVSYWSRTVIVPLLV
LMALQPRARNPGRVAIDELFLEPPQTIGLAPKAPQQKAAWFWVFRAVDAVLRFAAPRFPK
RLRQRAMQCAVSWVTERLNGEHGLGAIFPAMANSVMMFDALGYADGHPHRAIARRSIEKL
LALRDHEAYCQPCVSPVWDTALACHSLLEVGSDQAVTQVRKGLEWLAAKQILELKGDWIA
RRPDVRPGGWAFQYANPHYPDVDDTAVVVMAMDRAQRLSSQDDFRASIATAHEWVLGMQS
NNAAWGAFDADNEHYYLNNIPFADHGALLDPPTEDVTARCISMLAQIDESAPNSAAVARA
VDYLRRTQTAEGSWYGRWGMNYIYGTWSVLCALNAAGVDHASPELRRAAAWLVKIQNSDG
GWGEDGMSYRLDYRGHESAPSTASQTAWALLGLMAAGENDHPAVARGIDYLLRTQGEDSF
WNEPRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLKNTNARSVPHGI
>A0A552LEA6|squalene-hopene cyclase|EC 5.4.99.17|Microcystis wesenbergii Mw_MB_S_20031200_S109D|TrEMBL
MQIQDKITEIASKTAKAIELSQNYLLSTQYSDGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDLALEKAREFI
LAKGGISKTRIFTKMHLALIDCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKAVDNFAIE
TDNTYCVQPCVSPVWDTAWVIRALIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKSVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A5M8B587|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus cauae|TrEMBL
MRASIEAGNGGCQGKLACPARVRPCCYNRPTPNTDRGFARAGRGPAPPAASRCHCVTRSD
VAEIQIALTGSPPAVDPVDTQDRPDTVVSLAPSLPSFTAPTDLAGSRLDAAIAHAVDALI
ARQRPDGHWVFELEADTTIPSEYVLLVHYLGEAPDPAREGRIARYLLRRQNDDGGWPLFH
GGASDISASVKAYFALKMIGEPVDAPAMRRARERILALGGAEASNVFTRTLLALYGVMPW
RAVPLMPVEIMLLPLWFPFHLSKISYWARTVIVPLLVLNTLRPCARNPRRVGIDELFRRP
SQAARMPGRAPHQSRFWYAVFRGVDVALRVLEPLSPRALRQRAMQQAERFVRERLNGDDG
LGAIFPAMVNAVMMFDALGVPRDEPAVAQARAALDRLLVEHGGEGDETYCQPCFSPVWDT
SLTCHAMLEAGGERALAAARRALDWLLPLQVLDVRGDWTVRRPHLRPGGWAFQYANPHYP
DVDDTAVVAMALDRAARGDARWGGRVAPALARAREWIEGMQSSDGGWGAFEPENTHSHLN
SIPFADHGALLDPPTADVSARCLSMLAQLGELPANSRAAAQALRYLLDEQEANGSWYGRW
GTNYLYGTWSALCALQAAGLGPDAAPVRRAAQWLLSVQNEDGGWGEDGSSYRLDYRGHES
APSTPSQTAWALLGLMAAGCREQPAVARGIDYLLREQRADGLWDEQHFTAVGFPRVFYLR
YHGYARYFALWALARYRNLGNPGNLANPGDPGDPGNRGGLGSSADAAVPNDAAGRMPWGM
>A0A087PTX1|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter malorum|TrEMBL
MGNSLTHTVSSACEWLISQQKPDGHWVGPVGSNASMEAEWCLALWFLGLDDHPLRPRLGN
ALLQTQRDDGSWGIYLGAGNGDINATVEAYAALRSLGYPEDHPALHKASAWIAQKGGLRN
IRVFTRYWLALIGEWPWEKTPNLPPEIIWFPNKFVFSIYNFAQWARATLVPLAVISARRP
SRPLRPQDRLNALFPEGRANFDYTLPKKEGRDLWSDFFRTTDKGLHWLQSKFLKRNTLRE
AAIRHMLEWIIRHQDADGGWGGIQPPWVYGLMALHGEGFQFHHPVMAKALDALNDPGWRH
DKGDASWIQATNSPVWDTMLAIMALHDAKAEERFTPQMDKALGWLLDRQVRVKGDWSIKL
PDVEPGGWAFEYANDFYPDTDDTAVALIALASCRHRPEWKERGVEEAIARAVRWLVGMQS
SCGGWGAFDKDNNKTLLSKIPFCDFGEALDPPSVDVTAHILEAFGILGLPRDLPCIQRAL
AYVRAEQDPQGPWFGRWGVNYVYGTGAVLPALAAIGEDMTQPYITKACDWLAAHQQDDGG
WGESCASYMEVSAIGRGKTTPSQTAWALMGLIAAARPQDFAAIEKGCRYLIDRQEPDGSW
TEEEYTGTGFPGYGVGQTIKLDDPTLSKRLLQGAELSRAFMLRYDLYRQFFPIMALSRAS
RLITPNATAEKAINAARKNLAETVA
>A0A5R9LQG9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. So13.3|TrEMBL
MTATTDGSPGAPAPQAPSASTTSAPHPVHVGGAEAAAERAARRAAANLLAAQHPDGWWKG
DLETNVTMDSEDLLLRQFLGIQDERTTQAAARWIRSLQRDDGSWPTFHSGPGDLSATVEA
YVALRLAGDTPEAPHMANASAWVREAGGVVGARVFTRIWLALFGWWRWEDLPELPPEIIY
LPKWFPLNIYAFGCWARQTIVPLTVVAAHRPVRPAPFGISELHKDPAQPNPPRPPAPLAS
WDGLFQRLDRALHLYRKVGVRPLRRTALKACARWIIERQEDDGCWGGIQPPAVYSVIALH
LLGYELDHPVVRAGLDSLDRFAVWPDEDTRMIEACQSPVWDTCLATIALADAGVATDHPA
LVKAVDWMLDEQITKPGDWAVQRPGLQPGGWAFEFHNDNYPDIDDTAEVVLALLRVQHPD
PGRVDAAVEKAVRWNIGMQSKNGAWGAFDADNTSAFPNRLPFCDFGEVIDPPSADVTAHV
VEMLASLGLEDDTHTRRGIDWLLAEQEDSGAWFGRWGVNYIYGTGSAVPALVAAGLPVSH
PAVRRAVGWLESVQNQDGGWGEDLRSYSDQEWIGRGVSTASQTAWALLALLSAGERDSDA
VERGVRWLVDTQKADGSWDEPYFTGTGFPRDFSINYHLYRMVFPLTALGRYARSEPLGVI
GNVTKGKAAG
>A0A844RZQ3|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium yuanmingense|TrEMBL
MDSVTATSREALESSIASATQGILGFQQSAGHWVFELEADCTIPAEYILLRHYLAEPVDA
VLEAKIGNYLRRIQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDSVDAPHMVRAREAIH
ARGGAINSNVFTRFLLATFGVVTWRAVPVLPIEIVLLPFWSPFHLNKISYWARTTMVPLM
VIAALKPRARNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFLLFRSLDAILRVIEPLFP
KSLRKRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKDENFPPRAITRRGIDK
LLVIKDDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLDWLIPRQELEVKGDWA
VKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGAAGYDAAIARGREWIEGMQ
SDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETAKTSKQVAA
GVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDHKDPMIRKAAAWLTSIQNDD
GGWGEDAVSYRLDYKGWEAAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIATQDKKG
LWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A7V5CYF8|squalene-hopene cyclase|EC 5.4.99.17|Acidobacteria bacterium|TrEMBL
KPDLSATVKAYFALKLMGDSIDAPHMKKARDLVLSLGGAERCNTYTKFYLAALGQMHYDG
VPAIPPELVLLPKWFYFHLDKVSAWSRTMIMPLAVISSYRPVRQLPAPKGIMELYVNHDY
LHRPFVEFDKQLLSWRNLFLALDKALKLWEKTNLKPLRRSALRSIEEWILKRSDSRHSDG
LGAIFPPMVYIIIAFRCLGYSMEDPRVKEATQQLDRLMIEEGDTIRIQPCFSPIWDTGIA
TYALCEAGLNQEHECMRRAVDWLISKECRHPGDWMANVSRPVEPSGWYFEFNNSYYPDVD
DTAMVTMALHRSGCLQAKPPVQRGIQWILAMQNEEGGWAAFDRTINRPILEYVPFADHNA
IQDPACPDITGRTLECLGHLGFRPNHPAVKKALRFLEFEQEPEGCWFGRWGVNYIYGTYQ
VLCGLRTVGVDMNLAWIQKAGSWLRSVQKPDGSFGESPDTYEDPSLKGSGPSTPSQTAWG
TMGLMAVYGPNDPAVLRGIRYLVETQLPSGNWEEPWFTGTGFPRIFYLRYHLYRLYFPIM
CLGRWLNSYR
>A0A5C8LAR0|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus sp. N3.4|TrEMBL
MSVWSKVNEEIKHLTEMLEGIQQEDGSWHYCFENGILTDAYMIIVLRTLELPEEILIRQL
HDRIHGEQQYNGAWKVYPDEAEGNLDATVDAYYALLYSGYSQQTDESMIKAARFIKSKGG
LSQVNTLLTNVFLAATGQCAWPASLKIPIEFLLLPSSSPIHFFEFSGYARVHFAPILIMA
NLRLVLKNKATPDLSHLFVKDNNNSDSSSFSSIEGTDSPHGSNRLLDEIQNGIKQLTSLP
LKLRETAFKNAENYMLDRIESDGTLYSYSTSTLLMILALLTLGYDKRHHVITTALHGLSA
MLWQSSGKTHLQNSPSTIWDTALLSVALQQSGTTADQTSIRKSIHFLLGRQHNKQGDWSS
RIARPVPGGWGFSESNTINPDVDDTTAALRAIRETAKREPSYQGAWNRGLNWVLSMQNND
GGWPAFEKGVTNKLLTLFPIDGATAAAIDPSTADLTGRTLEFLGTTAGLDLSHTIIRKGI
DWLLAKQEIDGSWYGRWGVCYIYGTWAALTGLMAVKADSELPAVRKAVRWLLSIQNADGG
WGESCSSDRFNRYVPLGVSTPSQTAWALDALTAVCTEPLPAMEKGIQQLLVQLHLNDWTT
RYPTGLGLPGSFYTHYHSYRYIWPLITLNQYKKKFE
>A0A7W5F0H0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces violarus|TrEMBL
MRIAAPAACMPRWPHSALPAELAPATARLRSHLLDLIRPDGTLHSPCRSRVLESALLLAL
LDRARLEPPARSRLAAYLSLHCNSPEPLDRLMARAALHHRPGPAGLLDVEQFLARAPDFT
GPRKRALLHAVLTLLDAAPTDDEIATAPEAFSLHGLHTWARVQVTAVKAVLAHARGHRLI
DKGDLELLRSTQRPGTVWEANLLIHLSVLHALLPVPGQYPLVVEGVKTALQHQRPDGGMP
FICDENTWVTATAGVALHAAGAAAPVMDLIARRLVALQHPAGGWSYTDGVQLPDVDCTSV
AVEVLHLADPDTYRAPLRRALRALHALRGKDGGFPTYLTGAPSEACMTAAAANALSTQGP
AYHHEFETAMSYLASQQRPDGSFPPDWSSSRLHTVSRAVLAASHHPRRGPDSPAQHIIRK
AVTLVADCQNADGGWGQQDGDASDALSTAYALTALTTQNTPGPATRGAAYLLTQQRSDGS
IASIPDSIGPRPFGFTVPALADVFTLLALGHLTRRLEPAPCRIPPVTNADKGGGVIRSSP
ARHRAARRPSLNAASEVAVKDRGQLWRTPRLAGGHPVRRHQAAGKPTGLHNDSDQLLAFS
SAWTPGPHSG
>A0A3M9M3B2|squalene-hopene cyclase|EC 5.4.99.17|Flexivirga caeni|TrEMBL
MTDLLTGSTETSDGFAVSARATLDRAVQCLRDLQLPSGAWKGELETNVTMDAEDMMLRVF
LGIDTPDTRDQTARWIRSQQRSDGTWATFAGGPADLSTTVEAWIALRMAGDKPTAEHLVR
AREFIVTAGGLEQTRVFTRVWCALFGWWDWKDLPNLPPELLYLGKHLPFNIYDWGCWARQ
TIVPLTVVGTLRPKRRMTWNIDELRTHSGASRAPRSARSTADKASDVAFQQLDKALHVYH
RHALRPIRRGALRRAAEWIVARQEADGGWGGIQPPWVYSILALHALGYPLDHPVLSAAIT
GLDGFVITQDTPDGPVRRLEACQSPVWDTGLALNAMLDAGVDARDPALRKAADWLIDEQI
TAPGDWTVRRPKLPSGGWAFEYANDNYPDTDDSAIIVMGLSRVLTTRAPLQQQAVSRGIA
WTAGMQSKDGGWGAFDADNTSGWPARLPFCDFGAVTDPPSADVTAHVVEMLAAAGRSRGA
RCQRGVQWLLDHQESDGSWFGRWGANYVYGTGAVVPALVAAGVSPDSAAIRAGVRWLRDH
QNADGGWGEDLRSYDDPAWIGRGDSTPSQTAWALMALVAAGELGEPLQRGIDYLVKTQLP
DGNWDENRFTGTGFPGDFYISYHLYRLIFPVWALGRALRALRGGEQGDRPSLGLTAKESS
>A0A7R6W5F7|squalene-hopene cyclase|EC 5.4.99.17|Methyloprofundus sp|TrEMBL
MFTEDYNNMSVTSALDSAIKNAQDRLLSLQHSDGYWVFELEADCTIPAEYIMMMHYLDDI
DNKLQAKIANYLRRHQSTDGSYPLYPGGAGDISCSVKAYYALKMAGDTPEQPHMARLHDY
ILSEGGAAKANVFTRIALAIFEQLPWRGVPFIPVEIMLLPKWFPFHIDKVSYWSRTVMIP
LFILCTLEAKAKNPLNIDILELFVVHPDLEQHYFPERGLTNKFFLFLDALGRKSRVLVTK
RMHQTAVARAKDWFTERLNGEDGLGGIFPAMVNAYQAMLLLGMPADHEQVVTARKAIDKL
LVISDDEAYCQPCLSPVWDTGLALLALQEANLPTTKANRERAYSWLKSKQLADEPGDWRI
QRPNIEGGGWAFQFENPHYPDVDDTAVVAFGMATAEIDGMDESIHRATRWIIGMQAANGG
YGAFDVDNTYYYLNEIPFADHGALLDPPTVDVSARCVMLMAKVAQNHDEYLPAYRRCIKY
IRDEQEADGSWFGRWGTNYIYGTWSVLIALEQTNIAKSDPVYTKAVTWLKSVQNADGGWG
EGNDSYLDASTKGQFHTSTAFQTAWAVLGLMAAGQTNSLAVKSGIDYLLSEQLEDGLWHD
DCHTSPGFPRVFYLKYHGYDKFFPLWAIARYRNEQNKK
>A0A6G3TBV6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces rubrogriseus|TrEMBL
MTATTDGSTGASLRPLAASASDTDITIPAAAAGVPEAAARATRRATDFLLAKQDAEGWWK
GDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDSPDAPHMARAAEWIRSRGGIASARVFTRIWLALFGWWKWDDLPELPPELI
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPARPNPPRPLAPAA
SWDGAFQRIDKALHAYRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPEDHP
QLVKASDWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHH
DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAVEGLAHDPRTRRGIQWLLDAQEADGSWFGRWGVNYVYGTGSVIPALTAAGLPTS
HPAIRRAVRWLESVQNEDGGWGEDLRSYRYVREWSGRGASTASQTGWALMALLAAGERDS
KAVERGVQWLAATQREDGSWDEPYFTGTGFPWDFSINYNLYRQVFPLTALGRYVHGEPFA
KKPRADEAPAEATPAEVKGS
>A0A170PPE1|squalene-hopene cyclase|EC 5.4.99.17|hydrothermal vent metagenome|TrEMBL
MHQGFSEIGGSTAPLATVEAAVDRATAALANLQRDDGHWVFELEADATIPAEYVLLRHYL
GEPVDAGLEAKIGTYLRRIQSADHHGWGLFHGGAFDVSASVKAYYALKMIGDPIDAPHMA
RARATILAVGGAAAVNVFTRIQLALFAAGPWSAVPTMPPELILLPRWFPIHLSKMSYWAR
TVVVPLLVLGALQPVARNALGVKVDELYTGAKIRPGTKAADPKWLWTHGFNALDRVLKAG
NGLWPKKLRARAIKACVDFVLERLNGVDGLGAIYPAMANSVMMFDCLGYAEDHPARAIAR
QSIEKLLVIREDEAYCQPCVSPVWDTALAAHAMLEAGGDDAEARAGRGLDWLRPLQILDV
KGDWAEEKPDVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRAKTSHDQEAIDRGVEWTVGL
QSRDGGWGAFDADNSYHYLNNLPFADHGALLDPPTSDVSARCVSMLAQLGETRDSDRMRA
ALDFLAKEQMPDGSWFGRWGVNYIYGTWSVLCALNAAGFAPEEPIVAKAVDWLTRIQNAD
GGWGEDCESYALDYKGHTPAPSTASQTAWALLGLMAAGDVDSPAVARGIDWLAANQEADG
LWGQEMYTGGGFPRVFYLRYHGYPKYFPLWAMARYRNLKRSNTRRVAHGM
>A0A7G3E4A1|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus thiaminolyticus|TrEMBL
MIDTVTGIGWIIETLRKEQSPDGAWAYPFDTGISTDAYMIILLRTLEIDDEELIEGLCRR
ILSKQQQNGAWKLFYDEGEGNVTSTVEAYYGLLFSGLYRKEDERLRAAKKFILAHGGLSE
VSMFTKIMLALTGQFQWPSFTPLPIEMILLPLNFPINFYSFSVFGRANLTPIMILADQKF
SMKTVYAPDLSDLKWSREDEEQWGRSKEWRSLLSCIQDGVNRLIGIPRELRRLALERART
YMLDHLEQDGTFYSYYSSTFLMIFALLSLGYKKTDPIITKAVEGIRAMKCEINGLPHMQY
TTANVWNTSLIGYTLQAAGVSHEDPMVTKANKYLLSRQHYRFGDWIVHNPSGMPGGWGFS
DVNTMNPDVDDTTASLRSISTIASQHPTTWARGISWLLPMQNDNGGWPAFEKNTDSKVLE
VLPLEKGRFLLLDPPCADLTGRTLEFLGNYTNLPASHSVIRNAVHWLLKDQRKDGSWYGR
WGICYIYGTWGAVTGLKAVGVAKNHPSMQKAAAWLRSIQNADGGWGESCRSDIQMTYVPL
KTSTLTDTAWALDALIAIADRPTTAIQKGITFLLDSLEKEDWTTDYPKGQGMGGAFYIHY
HSYRYIFPLLALAHYRRKFE
>A0A4Z0NJI9|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium nonmethylotrophicum|TrEMBL
MGKVETLHRKSTQNVTLDEVERRVSAASRALVQLAHADGHWCFELEADATIPSEYILYHH
FRGSVPERELEEKIAVYLRRTQSALHHGWALVHEGPLDISATVKAYFALKMIGDSPDAPH
MRRARDAILKRGGAAHANVFTRTLLALYGEVPWSAVPVMPVEVMLLPRWFPFHLDKVSYW
ARTVMVPLFVLQAKKPRAKNPRGIGVRELFTQEPERVRRWPSGAQESSPWRPVFAVIDDI
LRVVEPAFPAGPRAKALDKAVAFVSERLNGEDGLGAIFPAIANSVLMYEALGYPEDHPLV
VTARSAVEKLVTVKEHEAYVQPCLSPVWDTALAAHALMEAGGPEAERQARAALEWLKPLQ
VLDIKGDWAARKPDVRPGGWAFQYNNPHYPDLDDTAVVAMAMDRARTRLGPGEGGSDYTQ
SIARAREWIEGLQSRDGGFAAFDADNTYHYLNYIPFSDHGALLDPPTADVTARCISMLAQ
LGETKATSPALARAVDYLLADQEEDGSWYGRWGMNYIYGTWSALCALNAAGQDPASAPIR
KAVEWLVSIQNPDGGWGEDAASYKIEYRGYERAASTASQTAWALIALMAAGEADNPAVAR
GINYLARTQGADGLWGEEFYTGTGFPRVFYLRYHGYAKFFPLWALARYRNLQRGNSRRVA
VGM
>A0A372K8R5|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia sp. DHOC27|TrEMBL
MNDLSLAQPMDDDTPDTSVDAQPDVDAATPAAARADANVSPLDAAVTRATDAILAAQRPD
GHWVYELEADATIPAEYVLLVHYLGETPNVELEQKIARYLRRIQLPNGGWPLFTDGDLDV
SASVKAYFALKMIGDPEDAEHMVRAREVILANGGAEAVNVFTRILLALFGVVSWYAVPMM
PVEIMLLPQWFPFHLSKVSYWARTVIVPLLVLNAKRPVARNPRGVRIDELFHGAPVTTGL
PPRAPHQSQGWFTFFRGVDHVLRLIDGLFPKYTRERAVQAAVNFVDERLNGEDGLGAIFP
AMANSVMMYDVMGYPADHPNRAIARQSIEKLLVIKDDEAYCQPCLSPVWDTSLVAHALLE
TGEPRAERAAEHGLQWLRPLQILDVRGDWISRRPDVRPGGWAFQYANDYYPDVDDTAVVV
MAMQRSATVTQSDVDREAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALL
DPPTADVSGRCLSMLAQLGELPANSEPARRAYDYMLNEQESDGSWYGRWGMNYIYGTWSA
LCSLNAAGMSHDDPRIKRAAQWLISIQNADGGWGEDGTSYKLNYRGYEQAASTASQTAWG
LMGLMAAGCVDHPAVERGIEYLMREQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLW
ALARYRQLKRDGLTRVAVGM
>A0A523GMX7|squalene-hopene cyclase|EC 5.4.99.17|Betaproteobacteria bacterium|TrEMBL
MKSLDTLTGATREDTNFFHTGEVYSAHQRSSNQDIATLADALATARTALLSLQKEDGHWC
FPLEADCTIPAEYVLMMHFMDDVNVELETKLARFIRNKQDPKHGGWPLYYGGHFNLSCTV
KAYYALKLVGDSPDAPHMVVARTAILEHGGAARANVFTRILLAMYGQLPWRGVPFMPVEI
ILLPKWFPFHLRKIAYWSRTVTVPLTILCSLRAHAVNPRKINVRELFTVDPEKEHNYFPV
RTFLNRIFLLIERTASLFEPLIPNALRRVALHRAERWIVERLNGECGLGAIFPAMVNANE
ALALLGYPYEHPYRKQCRQALLGLLVDEGEQIWCQPCTSPVWDTILASLSLQEDIGADQK
PVRDALDWLVPLQILDAPADWQEENPKLAGGGWAFQYANPHYPDLDDTAAIAWAMYQADP
QAYRESITRAAIWLSGMQSRNGGFAAFDVDNTYYYLNEIPFADHGALLDPPTSDVTARCT
GFLALYGKPEQQNSIKQGLSYLFNEQEPSGAWFGRWGSNYIYGTWSVLEAFQLAKVDTAH
ESIIRAAQWLKSVQREDGGWGENNDTYFNPQLAGQFETSTSFQTAWALLGLMAAGETHSP
EVRKGIEFLLNKQDSDGLWNDPWFTAPGFPRVFYLKYHGYSKYFPLWALARYQAFTQRDL
V
>A0A3R9XNP8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. WAC05950|TrEMBL
LETNVTMDAEDLLLRQFLGIRDEATTYAAALFIRGEQREDGTWATFHGGPPELSATIEAY
VALRLAGDPPDAPHMSRASAWIRASGGLAAARVFTRIWLALFGWWSWDHLPELPPELVFL
PPWVPLNIYDFGCWARQTIVPLTVVSALRPVRPAPFALDELHTDARTPYPATPMAPLTTW
DGAFQRMDRALHVYRRFAPRRLRKAAMDTAARWIVERQENDGCWGGIQPPAVYSVIALHL
LGYDLGHPVMRAGLESLDRFAVRREDGARMIEACQSPVWDTCLAAIALADAGVRPDHPAL
VKAADWMLGEEITRTGDWAVRRPGLAPGGWAFEFHNDTYPDIDDTAEVVLALRRIRHPDP
VRLDAAIARGVSWNLGMQSKDGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAFEGRAGDARTRRGITWLLDAQEPDGSWFGRWGTNYVYGTGSVVPALTAAGIAPGHP
AVRRAVRWLESVQNEDGGWGEDQRSYKDRSWAGKGASTASQTAWALMALLAAGERDGKAV
ERGIAHLVGTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLYGEPSAPAG
SAPGGP
>A0A7Y9GHX4|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura citrea|TrEMBL
MTTTDVSGLTGAAAAVEAARDHLIGLQSPEGWWKAELETNVTMDAEDLLLRQFLGIRSDA
DTKDAARWIRSRQRDDGTWANFHGGPADLSTTIEAYVALRFAGDPVDAGHMREAAAYVRE
AGGIEGSRVFTRIWLALFGQWSWNDLPVMPPELMFLPSRVPLNVYDWACWARQTIVPLTI
LGSLRPVRALPFDLPELRCGVMPAKDARGWGAAFNALDRVLHVYERRPVRPLRRAALRRA
ADWIIARQEADGCWGGIQPPWVYSLMALHELGYGLDHPVIRRGLDGLERFTIRDERGRRL
EACQSPVWDTVLAMNALADAGVAADHPSLLRAAEWVVGEEVRGPGDWSVKRPDVPPGGWA
FEFDNDVYPDTDDTAEAILALRRASFPKAEEPIRRAVRWLDGMASRDGGFGAFDADNTRE
LCTKLPFCDFGAVIDPPSADVTAHVVEALSKEGLAESAVVRRAVVWLLRAQEADGSWFGR
WGANHVYGTGSVVPALVAAGVRPGRPAIRRAVVWLEDHQNPDGGWGEDLRSYDDPAWIGR
GGSTPSQTAWALLALLAAGERTPAVEAGVRWLVDHQRPDGNWDEEQFTGTGFPGDFYINY
HLYRLVFPVSALGRYLDGAT
>A0A8F6DHW3|squalene-hopene cyclase|EC 5.4.99.17|Sphingosinicellaceae bacterium|TrEMBL
MTVAGSLASRAGELDVAVERAASALAALQKSDGHFVFELEADATIPAEYILLRQYFAEPD
DPELEAGVARYLRRIQGDHGGWGLHYGAPFDISATVKAYYALKMIGDPVDAPHMVRARQA
ALAAGGAAAVNVFTRIQLALFGAGPWSTIPTMPPEIILLPRWFPVHLSKMAYWARTVIVP
LLVLQTLQPVAKNPRGIRVDELFLPRATVKPKSNVAGGKLVWKLGFGALDWLLKRGNGLW
PKALRARALQACRDFVADRLNGDDGLGAIYPAIANSAMMFEALGDTARRDIARSAVEKLV
VRRDDGEIYCQPCFSPVWDTALAAHALLETRAPEAETQALAALDWLVPRQVLEVKGDWAE
NAPNLRPGGWAFQYANAHYPDLDDTAVVVMGMDRARGLAGERYDQPVARGVEWTVGLQSR
DGGWGAFDADNSYHYLNNIPFADHGALLDPPTADVSARCVSMLAQIGETDTPRMAAALGY
LCKEQEADGSWFGRWGVNYIYGTWSALCALNAAGLGADDPAIARGAAWLAQVQNPDGGWG
EDCDSYALDYAGYTPAESRASQTGWALLGLMAAGATDSVAVRRGIAWLQAHQEPGGLWPE
EHHTGGGFPRVFYLRYHGYAKIFPLWALARYRNLSLGNETSTRWGM
>A0A7C5ABK4|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MKKTEGGVIPSPEERLTALPEMVLERAVEALLSIQNSDGHWAGELEGDTILSSEYILCHY
FLGWEERDRDELTKCLNFMRRQQEDEGGYALYPGGPADVSASVKAYFALKLFGDDPDAPH
MAKLRRKIQRLGGLLACNTFTKIQLALFGQVDWKECPAVPPELILFPRWFPFNIYEMSSW
SRTIVIPLSLIWATKPLCPVPEGKDIQELRVSLEDAPEYRTLEVEGTSRTWQLVFQSIDK
AAKLAESLTGRLRRRPLRALAIRKALDWMSARFENSDGLGAILPPIINSLIAFKALAFSE
DDPRFQMARRALKGLRVPGQLDDEIRIQPCHSPVWDTAIAVNALALAGGEDVKSSLEAAV
RWLLDREVRSPGDWAERVRDVEPAGWYFEYKNEYYPDVDDTIMVMMALERVDAPEARPAI
ERAMRWVRAMQSKDGGWAAFDRDNNRWILANVPFADHNAMLDPPTADITARTLEMMGLFG
IRKDDPQAAHAIQFLKDTQEPEGSWYGRWGVNYIYGTWQVLRGLAEIGEDMSQPYIVRAA
DWLESVQNEDGGFGETIASYEDRSLMGRGPSTPSQTAWAMMGLIAAGRARGTSLRRAVEY
LVTSQRADGTWEEELWTGTGFPKVFYLRYYLYSLYFPIMALAMWRDALRGATLVQQQART
AAEQEA
>A0A429Y2A3|squalene-hopene cyclase|EC 5.4.99.17|Siminovitchia acidinfaciens|TrEMBL
MSYNTGEPASKIIETLKGDQSADGSWDYPFDTGVKTDAYMIILLRSLEINDEHLIRGLTE
RILSKQEKNGAWKLYYDESNGNLSYTVEAYYALLYSGLYSKSDSRMRLAKSFILKKGGIE
KAELFTKVMLALTGQYKWPHFFPLPVELILLPLSFPFNFYDFSVFGRANLTPIMILAAKK
YQLKTKNSPDLSNLFLSRTHEFFSANEKREFDNIFNTIQHGIKSILMAPQQIRSLAIERA
KRYMLNHLEPDGTFYNYFSATFLMIFALMSLGHKKDDPIILKAVDGLKAMECTIKGHPHI
QYTTANVWNTALISFTLQNAGVQPTDPTILAANEYLLERQHFKYGDWVIHNPSALPGGWG
FSDVNTFNPDVDDTTAALRAFSPLVTEDSALRSSWDRGANWVLSMQNNDGGWPAFEKNVD
KKIMNLFPMDRARFLVSDASSADLTGRTLEFLGNYTNMPKKNGKIKDGINWLISNQKKDG
SWYGRWGICFIYGTWAAVTGLMAAGMDREQNCIRKAVTWLKTIQNKDGGWGESCRSDIEN
KYVPLGKSHVTQTAWALDALIAAEKQPTSEIKAGVEYLLQLYDKEDWTKDYPVGQGMGGS
FYIHYHSYRYIFPLLAISNYEKKFSQ
>A0A3M1BA12|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MMDRIFPHLRLRRYSIPRNFNKALENFKSGQISPPLVGGSHPSFPRQRELEQAIVRTVSY
LRDIQDGAGYWVGELESNVSITAEYLMLFHYLDCVDEEKEKAMVNYLLREQLENGAWSIF
YGHLGDLSTTVEAYFALKLAGLSPEDSRMRKAREFILSNGGMLGCRAMTRICLGLFGEFD
WRGIPIMPVELMLMPPFFLFNIYNFSSWARAIVVPLLVLFSLRPIKELPPEKRLDELYPI
PKEELDYSFERSEKWISWRNFFVYTDKVLRFVEKSPVKFTRSLALKKAEQWILDHQLETG
DCAGIFPAMANTLMALHALGYSLHSKPIQKGLEALERFEIREGDTLRIQACVSPVWDTAW
TAYALSTAGYTAKEDFLAKALDWLFEQQVDVEGDWIIRNPGVVPGGWAFEFHNDLAPDTD
DTAVVLMALLGDDLESNPQKLEEFKRGLNWLLSMQNDDGGWGAFERNNNQFIYNEHPFSE
SDNLLDPSTSDVTGRVLEAVGQMGMNKRHPMVRKALQFLRKEQEAFGAWYGRWGVNYIYG
TWSVLAGLRSVGEDMSQSYVQKAVSWLKSIQNDDGGWGESCLSYVDPDWIGKGNSCASQT
AWAVMALLAAGEVKSDSLQKGVDFLLRTQQKDGSWQENEFTGTGFPEFFLIKYHMYSIYF
PLLALARYRRYLFFTQEEK
>L0RFX3|squalene-hopene cyclase|EC 5.4.99.17|Maridesulfovibrio hydrothermalis AM13 = DSM 14728|TrEMBL
MNTENSKNKKNRRQIVPLLQPKDAMKRVAKRFRSLQSPDGYWVFALEADVTIPSEYIMFN
RFLERKIDPAVAKRLGNYIRSKQMPDGGWPLHDEDGPINISASVKAYMALKMLGDDKDAE
HMVRARRTILAKGGAETSNVFTRICLATFGQIPWHCPPAMPIEIVLLPKWFFFHLDKVSY
WSRSVIYPLLIIYAKQPVCKLRLEEAIPELFCKPAEEHIHIDKYRDKSWRKNAFILLDRI
LKRTLHLIPDMIHNKAIKYAEKWTREHMAGRGGIGAIFPAMANAVTAMHLLGYDESDPDF
ARGLKAVDDLMVDKFQSSDNSPREYTVVTGGRELSAAPELDISPGKGTAENLEQCMCQPC
NSPIWDTCLTLSAMMEAGEDQNSKLTQQSIKWLWDQQIFFKGDWKSKAPKLEGGGWAFQF
ENTFYPDLDDTAMVLMAMARAGVLENKDNHENFVKGVNWLLGMQSSDGGYAAFDIDNCAL
YLNDIPFADHGALLDPPTSDLTARVIELLGVIGYDQNFKPIRQGIEFLKKEQEEDGSWFG
RWGVNYIYGTWSVLCGLRQVGEDMNSPYICKAVEWFENHQNKDGGWGESCLSYNNQNYAG
LGDSTPSQTSWALLGLMAAGKVNSKAVSRGIRYLLETQKEDGSWNEKHFTGTGFPKVFYL
RYHGYSQYFPMWALGVYDRFSAGEDTKQIMMRLDAPLDLGRKW
>B3E4L3|squalene-hopene cyclase|EC 5.4.99.17|Trichlorobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ)|TrEMBL
MKSRKYPISHALTSFNHTTVAPVEAPAPISVKSPAKVHRLPSSIWKKMEGSAGNPLDKAV
ELTRDFFFREQLPDGYWWAELESNVTITAEYIMLFHFLGMVDKDKERKMANYLLRQQTEE
GYWTVWHNGPGDLSTTIEAYFALKLAGYHADHIALRKARDFILANGGILKSRVFTKTFLA
MFGEFSWLGVPSMPIELMLLPDWAYLNVYEFSSWARATIIPMSVLMANRPVYKLPPHARV
QELYVRPPRPTDYTFTKEDGIFSLKNFFIGVDHLLKIYESSPIRPFKKRATEKVEQWILE
HQEKTGDWGGIQPAMLNAILALHCLGYANDHPAVAKGLEALANFTIEDSDSLVLQSCISP
VWDTALVLQAMQEASVPLDHPSLIKASQWLLDREVRIKGDWKIKSPDLEPGGWAFEFQND
WYPDVDDSTAVMIAIKDIKVKNTKARQDAIRRGIDWCLGMQSENGGWAAFDKDNTKHMLN
KIPFADLEALIDPPTADLTGRMLELMGNFGYTKDHPQAVSALEFLKNEQEPEGPWFGRWG
VNYIYGTWYVLIGLEAIGEDMNSPYIKKSVNWIKSRQNLDGGWGEVCDSYWDRTLMGCGP
STASQTSWALMALMAAGEVGCQAVERGIQYLLATQNSDGTWDEEAFTGTGFPKYFMIKYH
IYRNCFPLTALGRYRRLTAGTHAQ
>A0A218PS14|squalene-hopene cyclase|EC 5.4.99.17|Hyphomicrobium sp. GJ21|TrEMBL
MTTNAAATSARSREDAIRQVSGQQLETAIASARNSLLALQRPDGHFVFELEADATIPAEY
VLMRHYLAEPVDAVLEGKIARYLRRIQSDDGGWPLFRDGASNISASVKAYYALKMIGDAP
DAPHMQKARAWILAQGGASHSNVFTRNLLALFGAIPWSGVPVMPVEIMLLPKWFPFHIDK
ISYWARTVLIPLTVLNALKPVARNPKGVGIAELFVTPPDQVRNWPKGPHQKFPWSQVFGG
IDRVLRLFEPAFPKSLRKKSIDKAVAFATERLNGEDGLGGIFPAMVNALLVYDALGYSHD
HPDYVTARGSIEKLLVIKDDEAYCQPCLSPVWDTALAAHALMESGVAQADEDVDRALAWL
KPLQVLDTVGDWAASRPDVRPGGWAFQYANAYYPDVDDTAVVVMAMDRAAGGDAAKRDHY
RESMARGREWVVGVQSKNGGWGAFDADNTYEYLNQIPFSDHGALLDPPTADVSARCVSML
AQLGERRETSPVLDKALRYLESTQEKDGSWYGRWGMNYVYGTWSVLCALNAAGVEPSAPS
MRKAADWLLSIQNPDGGWGEDGESYSLDYKGYEAAPSTASQTAWALMGLMAAGEVDHPAV
QRGVAYLAAKQGSDGFWGEERFTATGFPRVFYLRYHGYSKFFPLWALARYRNLKAANSKS
VLVGM
>A0A7W5NK46|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia sp. WP4_3_2|TrEMBL
MNDLSQAMPADDPAHARAAALAFDGDAPHGAASAEELAHDASLAAGLDDAVARATDAILA
DQHADGHWVYELEADATIPAEYVLLVHYLGEQANLELESKIARYLRRIQLPGGGWPLFTD
GDMDVSASIKAYFALKMIGDAEDAQHMVRAREAILAAGGAEKANVFTRILLALFGVVTWY
AVPMMPVEIMLLPKWFPFHLSKVSYWARTVIVPLLVLNAKRPVAKNPRGVRIDELFRSAP
VSTGLNERAPHQSPAWFGLFRAVDGVLRVADPLFPSYLRQRAIDAAVAFVDERLNGEDGL
GAIFPAMANAVMMYDVLGYPADHPHRAIARQSIEKLVTIHADEAYVQPCLSPIWDTSLAA
HALIETGDARARAAARRGLEWLLPLQILDVRGDWISRRPDVRPGGWAFQYANPHYPDVDD
TAVVVAAMDRIDKLDKTSDFDEAMARAREWVVGMQSSNGGWGAFEPENTHEYLNNIPFSD
HGALLDPPTADVSGRCLSMLAQLGELPVASEPARRAYHYILAEQEADGSWYGRWGMNYIY
GTWTALCALNAAGLEHHDSRMRRAAQWLIAIQNDDGGWGEDGTSYKLDYRGYERAASTAS
QTAWALLGLMAVGEVNHPAVARGIAWLQQTQREHGLWDETRFTATGFPRVFYLRYHGYRK
FFPLWALARYRNLKREGTTLVKAGL
>A0A661UZT4|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MRASREALDEAIRRTQDYFLRTQHPSGYWLGDLESNVCMAAEYLLLTHFLGVRDDERWRK
VTNYLRRQQRPDGTWAVYHGGPSDLNATVESYFALKLAGVSPAEPAMARAREWALSAGGV
PKVRVFTKIWLALFGQWDWRGVPVLPPEMIFLPRWLPLNIYDFASWARATIVPMLIILSE
RPTCPVPESARIDELFPDGREGTDYSLPAPQDSPWGSLFHHADGLLRRLDRFAPGATREA
AYRAAEDWIVAHQEADGTWAGIQPPWVYSLLALKVRGYPLDHPVMRRGLEAFDSGWAIED
DETFNPQACVSPVWDTVLAMNALLDSGVAPDHPALVHAAHWLLGEQVLTGGDWQVGAPGV
EPGGWAFESENDLYPDTDDTAEALIALARVRLPDERRKNEAIERGRRWLIGMQSANGGWG
AFDRDNTRRLVNEIPFCDFGEVIDPPSEDVTAHVIEALALLGDGDSGPVQRGLRYLRREN
RPDGSWFGRWGVNYIAGTGSVLPAFRAAGCDMSKRRFQRSVGWLTGTQNEDGGWGEDPRS
YADESWAGRGESTPSQTAWGMAGLHAVAGDGLVADSLERGARWLIEQQEEDGQWLEPQFT
GTGFPGDFYLRYDLYRNYWPLLALGRYRDALSKS
>A0A6L7X9V6|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MASTASIPVSDGALSHSIRRATDWLVEEQDAAGFWWGELESNPSITAEYLLLTHHLGIGD
RQQWNGIARYIRAQQQPEGFWAQYLNGPGDISTSVEAYFALKLAGDDPDSPHMTRAREWI
LDQGGIMAARVFTKIWLALFGEFDWDRLPAMPPWINLLPSWLPINLYEFASWARATIVGI
TVIMTLRPTAALPAGAGVPELWVKQSDRRKFAVPPPKNPFSAKGAFYVFDVLLRFLDRNR
IRPFEHRALAFSERWLLDRQEADGCWGGIQPPWVYAILALRAMGYSLDHPVIRRALSGFD
RFTWNQAGPEGEQIWTESCQSPVWDTCLAAVGLLDAGLDPQHPTLQKAARWMLREQVLSG
GDWQVKNPDTPPGGWAFEFDNDVYPDVDDTAVVLMALERIPMPGLESERQLALDRGLHWM
LSMQSSNGGWGAFDVDNEKTFLADIPFADFGELLDPPTADVTAHALEYIGQLGYSGQYPP
ASRGLRFLYDLQEPDGSWWGRWGVNYIYGLGAALPALQALGEPMSAPAVRNAVEWLFRRQ
LEDGGWGESCDTYADPSLRGLGPSTPSPPAWALMALIAAGEAEHESVARGIRYLVERQRE
DGTWDEPEFTGTGFPSDFMINYHLYRHYFPLMALGRYERAVAAR
>A0A4R4NVK3|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura bangladeshensis|TrEMBL
MTTLETPETPEAAAPRTAAEALEAARDHLLLLQSPQGWWKGELQTNVTMDAEDLLLREFL
GIRTDEDTAEAARWIRSQQAPDGTWANFHDGPPDLSTTVEAYAALRLAGDLPDAGHMIRA
AAYIRGEGGVPATRVFTRFWLAMFGRWSWDELPVVPPEMLFLPRWFPLNVYDFACWARQT
IVPLAVVGALRPVRPLPFGLDELVPDYDVPRPGKRRPTGWGAAFGALDKALHVHQRHAAR
RRPLKGVRDAALRRAGEWIVARQERDGSWGGIQPPWVYSLLALHLLGYGLDHPVIRRGLD
GLERFTIRDERGRRLEACQSPVWDTALAMNALADAGLNAGHPALERAAEWVIGEEVRGPG
DWSVRRPGLPPGGWSFEFDNDVYPDVDDTAEVVIALDRVRHPKAEPAIERGVRWMAGMVS
ADGGFGAFDADNTRTLCRKLPFCDFGEVIDPPSADVTAHVVEALAHRGMADSLLAKRAVV
WLLKAQEPDGSWFGRWGANHVYGTGAVVPALIAAGVRPEKPVIRHAVGWLARHQRDDGGW
GEDLRSYRDRSWVGHGTSTASQTAWALLALLAAGERGPVVERGIRWLVEHQRPDGTWDEE
HFTGTGFPGDFYINYHLYRLVFPLSALGRYLKGS
>A0A7S7TAK5|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. CCBAU 21365|TrEMBL
MLARDHSVAVDPVALEKSISKATEALLGYRQSDGHWVFELEADSTIPAEYILLRHYLAEP
IDAGLEAKIGNYLRRVQGAHGGWPLVHDGPFDMSASVKSYFALKMIGDSVDAPHMVRARE
AIRSRGGASGSNVFTRFLLALYGVVTWRATPVLPIEIMLLPMWSPFHINKISYWARTTMV
PLMVLAALKPCAKNPKGVGIDELFLEDPKSVRMAPKAPHQSPSWFYLFRSLDAVLRVIEP
MFPKRLRQRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYEALGKDESFPPRAITRRG
IDKLLVVGEHEAYCQPCVSPVWDTALASHALQEAGGDDTLAKAKQGLDWLKPRQVLELKG
DWAVKAPDVRPGGWAFQYNNDHYPDLDDTAVVVMAMDRVRRHTGTREYDEAIARGREWIE
GLQSRDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLGQLGETAESNRA
MADGVAYLRRTQLAEGSWYGRWGLNYIYGTWSVLSALNVAGVDRNDPMIRKAVDWLASVQ
NQDGGWGEDAVSYRLDYKGYEVAPSTSSQTAWALLGLMAAGEVENPAVARGVEYLKATQT
EKGLWDEQRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNSRVVGVGM
>A0A6M0JC20|squalene-hopene cyclase|EC 5.4.99.17|Nostoc sp. UIC 10630|TrEMBL
MRTQDRVKVNQVAEAIAASQQYLLSIQNPAGYWWAELESNVTITAETVLLHKIWGTDQTR
PLHKVEAYLRQEQRQHGGWELYYGDGGELSTSVEAYMALRLLGVPAKDPAMIRAKAFILK
RGGISKTRIFTKLHLALIGCYNWRGIPSLPPWIMLLPKAFPVNIYEMSSWARSSTVPLLI
VCDRKPVFITDPTINLDELYAEGVDRVRWELPQSGDWTDLFLTLDQGFKWAESLNLVPFR
EEGIKAAEKWILERQEATGDWGGIIPAMLNSMLALRCLNYDRSDPIVERGLQAIDNFAIE
TENSYRVQPCVSPVWDTAWAMRALVESGFAPDHPVVVKAGEWLLQKQILDYGDWAVKNRQ
GKPGAWAFEFDNRFYPDVDDSAVVVMALHLVKLPNEKIKQAAIARAVNWIASMQCKPGGW
AAFDLDNDQDWLNSIPYGDLKAMIDPNTADVTARVVEMLGACDLSIDSDNLERSLTYLLR
EQETEGCWFGRWGVNYIYGTSGVLSALALIDPQRHKLSIERGAAWLVGCQNPDGGWGETC
RSYDDPSLKGKGNSTASQTAWALIGLLAAGEATGKLALKAIEQGIGYLVATQQPDGTWFE
ADFTGTGFPCHFYLKYHLYQQYFPLIALGRYQAVMGLTNLSLF
>A0A5N6C651|squalene-hopene cyclase|EC 5.4.99.17|Microbispora catharanthi|TrEMBL
MTTGVATSAARAATALKAARDHLLGLQAPEGWWKGELQTNVTMDAEDLLLREFLGVRTDA
ETAEAARWIRSQQRSDGTLSGTWANFHDGPADLSTTVEAYAALRLAGDPPSAPHMRAAAA
YVRGAGGIESARVFTRIWLALFGQWRWEDLPVIPPEIMFLPPWCPLNVYDWACWARQTIV
PLTIVTAHRPVRRLPFGLPELRTGRPARRAPRTGWDAAFAALDRALHRYERHPVAGLRRA
ALRRAAEWVVARQEADGSWGGIQPPWVYSLMALHLSGYGIGHPVMRAGLAGLDRFTIRED
GTRRLEACQSPVWDTALAMTALLDAGLPRDHPALARAGEWLLREEIRGPGDWMVRRPRLA
PGGWAFEFDNDGYPDVDDTAEVILALRRWGRPDARPAVERGLRWMAGMASRDGGFAAFDA
DNTRELCLRLPFCDFGAVIDPPSADVTAHVVEALAAEGMARSPVVRRGVVWLLRAQEADG
SWFGRWGANHVYGTGAVLPALAAAGVRPGAPCVRRAVAWLEAHQHPCGGWGEDMRSYRDP
AWIGRGEPTASQTAWALIGLLAAGERGPSVDRGVAWLADSQRPDGTWDEPHYTGTGFPGD
FFINYHLYRLVFPVSALGRYLRLHETAGPEATP
>A0A5Q0BSG0|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Methylospira mobilis|TrEMBL
MLKQATTTRFDAALLGSLKDSPLDEAIARAREKLLGLQHAEGYWVFELEADCTIPSEYIL
MMHYMDEIDAGLQAKIANFLRGRQSADGSYPLFQGGQGEISCTVKVYYALKLAGDSIDAP
HMKRMREWILAQGGAARSNVFTRIMLAMFEQIPWRGVPFIPVEIMLLPKWFPFHLDKISY
WSRTVMVPLLILCTYRVKARNPGKVDVRELFVTAPEKEKNYFSHVKTPLGKMVLALERTG
RMLEPLIPSSMRKKATQRAHEWFTERLNGYDGLGAIFPAMVNAYEAMDYLGIPPDNEQRR
VALESIKRLLVINEDSAYCQPCVSPIWDTGLVSLALQEVDRYEDDPALREQIRHGLRWLA
SKQLHDEPGDWQVKRPGLSGGGWAFQFGNSYYPDVDDSAVVAHALIQSGEQEFDENVDRA
GAWIGGMQSGNGGYGAFDVDNTHYYLNYIPFADHGALLDPPTADVSGRCAMFLGKLAKQK
PEFRPVLDRCIDYLRAEQEADGSWFGRWGTNYIYGVWSVLLAYETAGVSTDDPSTRRAVA
WLKSKQRSDGGWGEGNESYHDDATRGDFHTSTAFQTGLALIALLAAGEAESPEVKAGVDY
LIKHQQADGFWKDQCFTAPGFPKVFYLKYHGYDKFFPLWALARYRNDICSVA
>A0A3M8CP71|squalene-hopene cyclase|EC 5.4.99.17|Brevibacillus panacihumi|TrEMBL
MKERVESEINRIVHRLQGSQSPDGAWRFCLESGPLTNAYMIILLRSLRIDDEEFISGLAQ
RIAALQVENGTWKLFHDEERGNLSATVEAYYALLYAGHSWNDEEHMLTAKQQILAKGGLS
QTSMLTKLMLSLSGQIPWDAHVTIPIEGMLLPHWAPFHFFDFVGYARVHIAPILILTDRK
LVIQTERTPDISELRIPSTADHHSFAARYLQKRIEDVIKFLPYTAQIHQEALNQAKQFML
KRLEADGTLYSYLTSTVLMIFALLSLGYPKSHPVITRAVAGLKTMACHRNGQIHMQDATS
TVWDTALLTHALQVSGVSASHPMLQKAGRYLLSRQQDKYGDWVLHNHAALPGGWGFSDSN
TINPDIDDTTAALRAISQMQKTDLVYQRAWQRGLNWLLSMQNDDGGWPAFEKNTNKQILS
WLPIEGADAVSTDPSTTDLTGRTLEFLGNHAGMNVRDPSIQKAVSWLLRNQEENGSWYGR
WGICYIYGTWSAVTGLIAVGVPAEHPAIQKAVQWLLRIQNQDGGWGESCNSDIVKSYVPL
GASTPSQTAWAVDTLIAASPTPTLPMIRGIQFLLGKEGNQDWTLSYPTGAALPGGFYFHY
NSYRYIWPLIALGHFQKKYG
>A0A6P0KRZ8|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIOASIH|TrEMBL
MQTQDRIVHSGVTEAIANSQSYLLAQQYPDGYWWAELESNVTITAEIILLHKIWGTDKQR
PLHKAEAYLRSQQRKHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDSALVRARDFILK
RGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPQWFPFTIYEMSSWARGSTVPLLI
VFDQKPVFQIQPSINLDELYTEGADHAKFELPRNSDWTDLFVLLDHGFKLAEDSNLVPFR
KQGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPVVQRGLEAIDRFAIE
TPDSYRVQACVSPVWDTAWVLRAMVESGLEPDHPALVRGGEWLLQQQILDYGDWVVKNPQ
GKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLKQAAMARGLAWIASMQCNQGGW
AAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEMLGSCNLSIESQQLEKAIAFLIQ
EQEADGSWFGRWGVNYIYGTSSALSALSKIAPHTHQRSIERGAAWLVKCQNLNGGWGETC
LSYDDPSLKGLGISTASQTAWALIGLMAAGEATGNWAMDAIEKGVNYLVSTQEPDGSWNE
TEFTGTGFPSHFYLKYHFYQQYFPLLALGRYQMSVSS
>A9W437|squalene-hopene cyclase|EC 5.4.99.17|Methylorubrum extorquens (strain PA1)|TrEMBL
MREAAVSKVETLQRPKTRDVSLDDVERGVQSATRALTEMTQADGHICFELEADATIPSEY
ILFHQFRGTEPRPGLEAKIGNYLRRTQSKVHGGWALVHDGPFDMSASVKAYFALKMIGDD
IEAPHMRAVRKAILQRGGAANANVFTRILLALYGEVPWAAVPVMPVEVMHLPKWFPFHLD
KVSYWARCTMVPLFVIQAKKPRAKNPRGVGVAELFVTPPDSVRTWPGSPHATWPWTPIFG
GIDRVLQKTQDHFPKVPRQRAIDKAVAWVSERLNGEDGLGAIFPAMVNSVLMYEVLGYPP
EHPQVKIALEAIEKLVAEKEDEAYVQPCLSPVWDTALNSHAMLEAGGHQAEANARAGLDW
LKPLQILDIKGDWAETKPNVRPGGWAFQYANPHYPDLDDTAVVVMAMDRAQRQHGLVSGM
PDYSESIARAREWVEGLQSADGGWAAFDADNNHHYLNHIPFSDHGALLDPPTADVTARVV
SMLSQLGETRATSRALDRGVTYLLNDQEKDGSWYGRWGMNFIYGTWSVLCALNAAGVDPQ
SPEIRKAVAWLIRIQNPDGGWGEDASSYKLNPEFEPGYSTASQTAWALLALMAAGEVDDP
AVARGVNYLVRTQGQDGLWSEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKRGNS
RQVQFGM
>A0A7C1PLK1|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Scalindua sp|TrEMBL
MTNLLLDFIEKIDKVSYKFLNGRNGRNLPEVLPDDLCFEKTLREIKGELSYDTELASAIR
KARSHLLKEQDKREGFWVGELEGDVALTAEYMMLMHFIDRVDIVKQKKAAKYLVETQQKD
GGWNIYYKGPSNLSVSVKCYFALKLAGYSKEKPFMKKARDCILNMGGIMESNTFTKIYLA
IFGQFDWQGIPALPIEVILLPNSFYFNIYEFSYWSRCIVVPLGIIMAMKPKHSVGGNAAL
DELYIIPRNKVSYRMARDQDKFSLKNVFINIDSVLRRYEKNPFRPLRKLAIEKAEKWILQ
RLEKSGGLGAIWPAMVNSVMAMKCLGYRDEHPDYRRALLEIEKLEVHDKETLHMQPCVSP
VWDTPWSIMALSESGLSNDHPALIKAGQWLLKREVRSFGDWSLKNPVEEPSGWYFQFANE
FYPDSDDTTVVLMALLLIDLPDKYKKREAILRGFKWLLGMQCRDGGWGSFDRDNNKEILN
RIPFVDWNALLDPSTGDLTARVLDLMAGLGYDKDYPPAGKAIEFLKKEQEEDGSWFGRWG
VNYIYGTWSALSGLHLIKEDMTQDYVRKAASWLKSVQNRDGGWGETIKSYWNESFKAIGK
STASQTSWAILGLLCTEERDSESVKNGIRFLTENQKEDGTWDEKEFTGTGFPKVFYLRYH
MYRSYFPLLALSRYRNTVK
>A0A345HXF2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces paludis|TrEMBL
MTATTDGSTGAVGPRAPSGNGTTDTARPDPGGDLRVAAERATARSVEHLLGRQDAQGWWK
GDLATNVTMDAEDLLLRQFLGLQDPRVTHAAGLFIRGEQRSDGTWATFYGGPPDLSATVE
AYVALRLAGDRPDDPHMARAAQWVRDRGGIAASRVFTRVWLALFGWWKWDDLPELPPELV
FLPKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHAAPTAGTAGPALAPVA
SWDGVFQRLDKALHLYHRVAPRRLRRGAMNAAARWIIERQENDGCWGGIQPPAVYSVMAL
HLLGYDLDHPIMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLSPDHP
ALVKAADWMIGEQIVRPGDWAVRRPGLTPGGWAFEFHNDNYPDIDDTAEVILALRRVGHP
DPERLDAAIERGARWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAYEGRAHHPVTRRGVEWLLAEQETFGGWFGRWGVNYVYGTGAVVPALTAAGLPPA
HPAIRRAVSWLESVQNEDGGWGEDLRSYREEGWIGHGATTASQTAWALLALLAAGERESK
SVERGIAWLAGTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPKAL
TALAGTRKAG
>A0A7X0FYX4|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura coerulea|TrEMBL
MTTTEPAAEPATEPARGPARGPLTAEPPAAGATARTRSAAEALAAARDHLLALQSPEGWW
KGELQTNVTMDAEDLLLREFLGIRDEEDTRESARWIRSQQAADGTWANFHDGPPDLSTTV
EAYVALRLAGDPPDAGHMVRAAAFVRGGGGIPATRVFTRFWLAMFGRWPWERLPVLPPEM
MFLPRWFPLNVYDWACWARQTIVPLTVVAARRPVRPLPFALDELYPGYDVPPARRRGPSG
WDAAFGALDMALHVYERHPARGVRRAALRRAGEWIIARQERDGSWGGIQPPWVYSLLALH
LLGYGLDHPIVRRGLDGLERFTIRDDRGRRLEACQSPVWDTALAVNALADAGLPAGHPAL
ERASEWLVREEVRGPGDWSVRRPGLPPGGWAFEFDNDCYPDTDDTAEVVLALGRAGHPMA
EPAIERGVRWMAGMASRDGGFGAFDADNTRALCRRLPFCDFGEVIDPPSADVTAHVVEAM
SHRGMADSQVVKRAVVWLLKAQEPDGSWFGRWGANHVYGTGSVVPALIAAGVRPGKPAIR
DAVAWLERHQRDDGGWGEDLRSYRDRTWIGHGASTPSQTAWALLALLAAGEHGPAVERGI
RWLVEHQRPDGTWDEDHFTGTGFPGDFYINYHLYRLVFPISALGRYLKEIS
>A0A5A7WA81|squalene-hopene cyclase|EC 5.4.99.17|Tardiphaga sp. P9-11|TrEMBL
MHSVSPEITIQNAALETSIASARQGLLKFRQPDGHWVFELEADGTIPSEYVLLRHYLGEP
VDAELEGKIANYLRRTQGKHHGWALVQDGDFDMSASVKVYFALKMIGDSTDAPHMVRARE
AIRSRGGAANVNVFTRFLLAMFGILSWRATPVLPVEIMLLPMWFPFHLNKMSYWARTTIV
PLMVLAALKPRAQNKKGIGIDELFLEDPSKVGGIKRAPHQSRAMFAFFTGIDILLRAAEP
YFPKKLRAHSIAKAVEFCEERLNGEDGLGAIYPPMANMVMMYEVLGFPADYPPRAIQRRG
IDKLLIVGEVEAYCQPCVSPVWDTALTAHAMLETGGDEAFGPAKEGLDWLATKQVLDVKG
DWAVKRPDLRPGGWAFQYNNAHYPDLDDTAVVMMAMDRARRQTGGKEYDVALDRGREWIL
GMQSSDGGFAAFEVDNLEYYLNNIPFSDHGALLDPPTEDVTARCVSMLAQLGDTVETSKP
LADGVEYLRRTQLAEGSWYGRWGLNYIYGTWSVLCALNAVGIDHQDSAFRKAVAWLLSIQ
NDDGGWGEDAVSYRLDYKGFEAAPSTSSQTAWALLALMAAGEVDNPAVARGTRYLMDTQT
EKGLWDEARYTATGFPRVFYLRYHGYSKFFPLWALARFRNLKSTNSKTVGVGM
>A0A845JYL1|squalene-hopene cyclase|EC 5.4.99.17|Nitrospinae bacterium|TrEMBL
MEKVTELEETSAAMGPSSSIEEALTRTIKRSQDYLLSCQYDEGYWVDELESNVTITAELI
FFMHFTDRLDLDRQEKIVNYLFHMQREDGSWPLFHGGLCDINSTVESYMALKMAGVPADR
PEMVRARNAIRKNGGIKKTRVFTKIFLAMFGQVPWDVCPAIPMESVLLPNRFYFNIYEIS
SWSRGTVVPLSVVRSLEPVHTLPEGRDVRELFTENDHDLDFTPVGLPFSSWGNTFIYLDK
IIKFAGKFPWKPFRKMAMREVEKWTLEHQEDEGDWAGIQPAMFNSLLALHLMGYSKDHPV
CVKGMEAVDRFLLEKEDRLWMQACVSPLWDTAICLNALMDSGISTDHPALVKAGEWILSK
QVVKRGDWQIKNPEAEPGGWAFEFYNEGYPDTDDTAEILLALNRLEIPDVRNKLGECQRA
MSWLLSMQSKNGGWGAFDTDNDKEVLNEVPFADHKALLDPPTIDVSSRILWMLSQWGFKR
EHPQVARALKFVKDNQELDGCWFGRWGVNYIYGTFLAMNGLAAMGEDMNQPFSRKAIQWL
ETHQNEDGGWGETCQSYEEPSLRGRGNSTASQTAWALLGLIAGGEAKGNAAKRGVEFLLR
TQNELGTWWEDEFTGTGFPVHFFIKYHMYQHFFPLMALGRYQQAIENR
>A0A7C1YST7|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MKTEIAYIHKIDAKHKVAQKSGKEESLSERIISSINRTTNYYLQCQHPEGYWWFELESNV
TITAEYLMLLKFLGIENPEREQKIVTHLLRKQRSDGTWAIYYDGPGEISATVEAYFALKL
AGYPEDSEEMTSARDFILKSGGIENCRIFTKIFLALFGNYSWERIPPFPVELILFPDWFP
FSIYAFSSWTRASLVPISILLHLRPVKTIEGARVDELYVSSPNGRKKPSNCMNFLIFSRH
IGKLLFKAPFRPLRNTALKRAEEWIVDHQEESGDWAGIQPAMVNSLLALFSLGYPLDHPV
IQKGLEALETFLIDKGDEVVLQSCISPVWDTALNCLALVEAGIPPKYPAIQLAAEWLLKQ
QIFRGGDWQVKRPDLDPGGWAFEFHNDHYPDVDDSAVVLMALQRAVGDNPSAKCAIERGI
NWVLGMQSSDGGWGAFDVDNNKEYLNRIPFADLEAMIDPSTADLTGRVLQMMGYYGYDKD
HPVAKKAIRFLRKIQEPDGSWWGRWGVNYIYGTWSVLSGLESIKEDFSQPWIQKAVQWLK
NCQNPDGGWGETCESYKNPSLSGHGPSTASQTAWSLLGLMAAGEWESPEISRGIQYLLKN
QQPDGTWEEEYFTGTGFPKYFMLRYHNYRNCFPLMALGRYYGWLQDQLRLPGKTSLQMS
>A0A7V3CFI4|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MSTSPKAQPRPLGPAAEPSLRESLDSSIQRAQQLLLRHQFPEGFWWYTLEANETIGAEYL
FLREFLGIPDPQLSRALCQRMLSQQRADGSWAIYYNGPGDLSTTVECYWALKMSGTPVDD
PAMVRARGFIRSHGGPTKVRVFTKIHLAMFGLAPWAAAPAMPYIFMMLPRWAPINIYEFS
SWARACIVPLLIVLNERPVHKLSIDLEELYPEAPADRDWSISSTEGDWFSIGKVFLSVDK
FLKNIEKIKIPRFKRGSAVKRCLRYIREHIEKTEDIYPAMAYSALALKTLGYPNEDPTMR
QCLKGLAAFHQLCDGDLLHIPKQAGADLDGDRRYLHQQCCISPVWDTPWAAVSLCDSGLN
PEHPALRRAAEWLVSKQITDVKGDWAVKKPRLKPGGWSFEFKNDYFPDVDDTLEVLSLFH
KIGYPSAEIKRSFDLGLDWLLGMQSKNGGWAAFDVDNDLHLVNKIPFSDHGACLDPPTPD
ITGRMLEFLALIGWDRESSVVQRALKFVYREQLECGAWEGRWGVNYVYGTWCVLQGLAAI
GEDLSDPRIQKAVTWLKRVQLHDGGWGESCAGYAEDRFVSLPYSVPSQTAWALMGLIAAG
EADSPIVERGIEFLIRRQNDHGCWDEREYTGTGFPGHFYIRYHGYRHYFPLLALGRYRRA
RPK
>A0A534UWU0|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MVRGAGSARAARRFVIGTGIAVERSGIDLVIERAQGWFEREQYAEGYWWAELESNATMDA
EYLLLTHFLGARDEEHWRGVAQDIRNYQRDDGSWAMYHGAPGDLSTSIECYFALKLAGDS
PEAPHLARARQFIRERGGIARARTFTRIWLALFGQWSWDDLPVMPPELMLLPASAPFSIY
RFSSWARGTLVPLLLLMNDRPVRPVPDSARLHELRVPGAAPRAPRDAIDRLFRAIDAALR
GYRRLPFHPFRQRARKAAEQWILAHQEADGSWGGIQPPWVYSLMALRALGHSLDHPALRK
GLDGMHDRWMLRHGDGRVRVQACLSPVWDTGLSLLALLDSGVEPSAPLVQRAARWLLREE
IRVPGDWCVQVQGVAPSGWAFEFENDLYPDVDDTAVVLLALLKAGAVDVALRERALHWVL
AMQSRNGGWAAFDKDNTSRLPALIPFADFGEMIDPPSADVTGHVVEMLGAFGIGRSHPAM
QRGLRYLYAQQEKEGSWFGRWGVNHVYGTGAVLPGLAAAGEAMDSLAVRRSVRWLSERQN
ADGGWGETCASYVDVEARGRGESTPSQTAWALLGLVAAGRADSKAANRGAHFLVDRQRSD
GAWDEESFTGCGFPGYGIGEEHGARIVEGRELSAGFMIRYHLYRNCFPLLALGRYRAALR
GTARAIPSEGGS
>A0A534SEC3|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MAQAITRASQYLFATQHARGYWHAPLEANATMEAEYVFFNRLLGRERPDVERRLAERLLA
LQQADGSWPIYHNGPGGPSTTIEAYFALKLTGMSATEPALVRARDFILGRGGLARAGVFT
RIWLAYFGQFPWAGVPSMPVELVLLPPWFPLNIYAMSSWARGTVVPLTLLLAHRPSVRLP
AEAAVAELWLRAPTRDDLAFARSPELVTTRNFFLAVDRALKTLAPLSWRGLRRRAVARAI
EWLLRHQDTNGQWGGIQPAMVNSVLALHAVGFAADHPAMMSGIQGVEDFLVECEGTLMYQ
PCVSPNWDTALAARALLDAGLDPAHPALGRAADWLVANQINRPGDWAVLNPTLEPGGWAF
EFANDWYPDVDDSAVILTVLDALPAAETAAGRRAIAYGLNWTLGMQSRNGGWAAFDTDNT
AAFLNRIPFADMEAMIDPPTEDVTGRVLHLMGTIGYRLDFGRARRAVEFLRRTQRSDGSW
WGRWGVNFIYGTWGALAGLERIGEDMRAPYVRRAVEWLATHQNPDGGWGETVASYDDESL
AGKGESTPSQTAWALLGLLAADGPSSPAVERGVDWLVRTQGPDGTWQERLFTGTGFPRHF
YLRYHLYRHYFPLMALGQYRARLAARGEG
>A0A7Y6GN68|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces fungicidicus|TrEMBL
MTATTNGPAGAAPSRPAPARTTAATTDTAALDGAAVEAAAERARARAADHLLGLQSPEGW
WKGDLDTNVTMDAEDLLLRQFLGIRDEATTRSAALFIRGEQREDGTWATFHGGPPDLSTT
VEAYVALRLAGDSPDAPHMTRAAHWVRSQGGIAEARVFTRIWLALFGWWPWDRLPELPPE
LIFLPPWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPADPAPRARFAP
LASWNGAFQRLDRVLHAYRKVAPRALRKAAMATAGRWIVERQENDGCWGGIQPPAVYSMI
ALHLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALADAGVPAD
HPQLVRAADWMLDEQIERPGDWSVRRPHLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVR
HPDTARMERAISLGVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDPPSADVT
AHVVEMLAAEGLAADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALVDAGLP
TTHPAIRRAVAWLESVQNDDGGWGEDLRSYREQGRMARGASTASQTGWALMALLAAGERE
SRAARRGVTFLAETQHEDGSWEEPYYTGTGFPWDFSINYHLYRQVFPLTALGRYTRGAAP
EGA
>T2AZA7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSRNGGWGASDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWYGRWG
>T2AYS4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVVALHRADSARYSEAIARGAERIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWYGSWG
>T2AY96|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
WDTGLAMHAVLEANSVPDKIIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQYWND
YYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQHIP
LADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWYGRWG
>T2B0A6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSRSGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLRRGQEVNGSWFGSWG
>T2B032|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGSAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGRWG
>T2AXH6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGLAAHAVLETLGGNTLLLNKSCDWLSKLQIKEHTGDWGWRRKGLRPGGWAFQYN
NKFYPDVDDTAVVGMALHRQNPEKYADTISRAEEGIIGMQSSNGGWAAFDADNEYYLLEN
LPFADHRALLDPPTADVTARCISFLTQIGTSNNHPISRGLEFLKRNQEEDGSWYGRWG
>T2AYA8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLATHAMLEANLSSGPRILENDSTSKACKWLEKLQIKDCAGDWAVWRPNLRPGG
WAFQYHNDYYPDIDDTAVVAMALHRTGNKIYEPALLRAAEWIIGMQSKNGGWAAFDADNE
YHLLENMPFADHGALLDPPSVDVSAHCISFLTQLGYDQTNGTIKRGIEYLKKNQEEDGSW
>T2AZM8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHASTEIETALNWLKEQQLSDEPGDWRIQKPGLSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTKNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGSW
G
>T2AZG9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTAICSNALLDSGLPTDHPALVRAGKWIVSKQVTKRGDWQVKNPKAEPGGWAFEFY
NELYPDTDDTAEILLFLNRVEILDNRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGKWGFNKQHTQVKRAIKFVKERQEIDGCWYGR
WG
>T2AZE1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAAHAVLETLGGNTLLINKSCDWLSKLQIKEHTGDWGWRRKGLRSGGWAFQYN
NKFYPDVDDTAVVGMALHRQNPEKYADTISRAEEWIIGMQSSNGGWAAFDADNEYYLLEN
LPFADHRALLDPPTADVTARCISFLTQIGTSNNHPISRGLEFLKRNQEEDGSWFGSWG
>T2B0G0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLAAHAMLEANLSSGPRILKNDSTSKACNWLESLQIKDCVGDWAVWRLNLRPGG
WAFQYHNDYYPDIDDTAVVALALHRTGNKIYDPTLLRAAKWIIGMQSKNGGWAAFDADNE
YHLLENMPFADHGALLDPPSADVSARCISFLTQMGHDQTNQTIKRGIEYLKKNQEKDGSW
FGRWG
>T2AY76|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAIVLRGLAEIASPAVDSSNSLANAVDWLLAREVRFAGDWSRRVQAVPSGWCFEY
ANCYYPDVDDTAMVLIAFSSWLKRHKACRGSQEKASEDSQGERIRHIRNAMRRGIQWLTA
MQNSDGGWGAFDRDNNHELLCKVPFADHNAMIDPSSPDLTGRVLEAYGSLGHGVGEPGVD
RAIEYLRETQEPDGSWFGRWG
>T2AYD7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTAIVSIALRESGISEDDPRIRESCDWLIDREIRFRGDWYHKNPVEVEPSGWVFEF
NNKWNPDVDDTAMVLMALRQTPTDNQQRRDESFKRGMEWMKAFQCRDGGWAAFDKDCTKS
ILEKVPFADHNAMLDPECADITARILELLGYEGYPVDDPQVKRGLAYLRSQQETDGSWYG
SWG
>T2AZT8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAAHAVLETHGGNTHLLNKSCDWLSKLQIKEHTGDWGWRRKGLRPGGWAFQYN
NKFYPDVDDTAVVGMALHGQDPEKYADTISRAEEWIIGMQSSNGGWAAFDADNEYYILEN
LPFADHRALLDPPTADVTARCISFLTQIGTSNNHPISRGLEFLKRNQEEDGSWYGRWG
>T2AXP1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAICSNALLDSGLPTDHPALVRAGKWIVSQQVTKRGDWQVKNPKAEPGGWAFEFY
NELYPDTDDTAEILLFLNRVEILDNRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVGSRILWMLGKWGFNKQHPQVKRAIKFVKERQEVDGCWYGS
WG
>T2B016|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLAVHAMLEAGEPKNGAQLNKAMRWMADRQVCDVSGDWATHRPGLRPGGWAFQY
ANDHYPDVDDSAVVAMALDRASDPKVKQGLPRAVEWIAGTQSKNGGWGSFDAENSHYHLN
HIPFADHGALLDPPTEDVTARCVGMLAQIGDEAGNDAIERGLSYLRETQQPDGSWYGRWG
>T2B080|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTCIAQLALLESGVAPDDPMVQSSARWLMDKQIFEMGDWQVRAKDTRPGGWSFEFD
NLIYPDIDDASIVVMALDQVLLPKAEEPRRTDSIQRGVEWMAGMQSKNGGWAAFDKDNNK
KYLTKIPFSDFGETLDPPSVDVTAHLLEMYGRLGYTREDRVVDRGFKYVISEQEEDGSWY
GRW
>A0A7Y4Z8Y1|squalene-hopene cyclase|EC 5.4.99.17|Methyloglobulus sp|TrEMBL
QPCVSPIWDTGLTSLVLQEVNRYEHNPKTQQAIKSALHWLVSKQLRDEPGDWQIQRPNLP
GGGWAFQFGNSYYPDVDDTAVVALALVQADERKFAENIERAGSWIAGMQSRNGGYGAFDA
DNNHYYLNHIPFADHGALLDPPTADVSGRCIMFLGKLVSKHPEYQAVIDNCIAYLRNEQE
TDGSWFGRWGTNYIYGTWSVLTGFETAGVPKTDPSIRKAVTWLKSKQRKDGGWGEDNVSY
HDPKIRGTHHTSTAFHTALALLALLSTGESGCPEVKAGVNYLLKNQQVDGYWNGTSFNAP
GFPKVFYLKYHGYDKFFPLWALGRYRNELIAAE
>A0A1E3FPT7|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia contaminans|TrEMBL
MIRRMTTATPSPWSALDTAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDLRQEKMARYLRANQRLDTHGGWALYVDGDPDVSCSVKAYFALKAAGDSEHAPHMVRA
RDAILKLGGAARANVFTRILLATFGQVPWRATPLMPVEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNISIRELFVMPPDEERRYFPPARGMRRLFLALDRTVRHVEPL
MPKGLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYANQMMQVLGYPDDHPLRRDCDNAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVAAAEDGEPGDARRALDERIARAY
DWLAERQVNDLRGDWIENAPADVQPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRTHANA
DGTNPYAPRVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRAEERASVARCIDYVKRTQQPDGSWWGRWGTNYIYGTWSVLAGLALAGED
KSQPYIARAIEWLRSRQHADGGWGETNDSYIDPKLGGTNGGESTSNFTAWALLAQMAFGD
CESDSVKRGIAYLQSVQQEDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GAAAARASAAQGATAVVKATDSVVA
>A0A149TVU4|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter senegalensis|TrEMBL
MAADGSAFSDAPVSKETLDRAVTNAHAALGKRQQADGHWVYELEADATIPAEYVLLEHYL
DRIDDALEQKIGNYLRRIQSKDHGGWPLYHNGKFDLSASVKAYFALKAVGDDINAPHMRR
AREAILDHGGAERTNVFTRCQLALFGDAPWRATPVMPVELMLLPRKAFFSVWNMSYWSRT
VVAPLLVLAALKPIAINPRQIHVRELFVTPPEVVKDWIRGPYRSVWGRVFKGLDTVLRPV
LPFIPTKTHDKAIKAAVDFIEPRLNGEDGLGAIYPAMANVVMMYRALGVPDEDPRAVTAW
KAVQKLLVIKDDEAYCQPCVSPIWDTGLSGHAMLEAASGPNGVAPEETLTELRKASAWLR
DKQILDVKGDWAINKPDLAPGGWAFQYGNDYYPDVDDTAVVGMLLHREGDPANAEALERA
RQWIIGMQSTNGGWGAFDIDNNKDLLNHIPFADHGALLDPPTADVTARCISFLAQLGHVE
DQAVIDRAIEYLRKDQEEDGSWFGRWGTNYIYGTWSVLCAFNAAGISHDDPAVVKAVEWL
RSVQGADGGWGEGCESYEGGAHGTYGESLPSQTAWATLGLMAAGRRDDPAVAKGMAWLAE
QQDENGEWHEDPYNAVGFPKVFYLRYHGYKQFFPLMALARYRNLESSNTRRVAFGF
>A0A6C1C9S7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces albus|TrEMBL
MTTTDAAGSVAGVEKSLALAAEALRRGQDATGYWKGDFETSLIGESGEVILRHYLRLPPD
ETVAAAARTILSEQTSTGGWASYHEGPDELLLSVFCYVALRLAGHTPDEPEMRAAAASIR
GNGGVEAVDNLLMLAWLALIGLWPWRDIPLIPPEIVLLPPSFPGNIYQVGAAARGILVAN
SLFMARRPVVPTGFGIRELLARPGARRLPRSPLVRCATTLSHWYARHPVRPLRRRAVRKA
TRWLVRTQERDGSWGGNWPQTANVVMGLDAAGYGQDHPVVEAAMAGLDRYVVHKDGHRRI
EMWTSVVMDTALALSASAMAGGPDAEEAARPAVRWLLDNQVTELGDWAVLTDDPQPGGWP
YEFTNNANPDADDTAFAVAALRRVHPRGSDPDVDAACERAGRWLLSQQGEDGGWAAFEPL
RWRLPGRDKLARIGFLEAPSADITGHVLEALGADGRAGTAAARRGIAWLRRNQRPDGSWP
GWWACYHLHGTSAAVTGLTACGIPGNDPAVRRACDWLVAHQRDDGGWGEDIRALHDPAWI
GKGTSTPSQTAWALLALIAGGRAGSASVRAGLDFLVRTQQDDGDWAEPWHTWVVHHDGLY
WRDSLLRLIYPVMAMSAYRAAVTGTEPR
>A0A6B0WII3|squalene-hopene cyclase|EC 5.4.99.17|Acidimicrobiaceae bacterium|TrEMBL
MDNHQAHQSVREAVERTQQYFLRTQRDDGCWWGELESNPTIEAEYIMLTRFLGSDEGDRT
GRVAADIRRRQQPDGSWRMYFGAPGDLSTTIECYFALKLAGDPPDAPHMAQARAFIIENG
GIPKSRVFTKIWLALFGQWDWRATPSMPPEIMLLPKWAPFNIYRFSSWARATIVPMTIVL
TLKPTRPPPAGAGIEELRRDGPEALAVSRFKPNPLSVQGGFLLMDRALRLWRGLRLVPGR
RRALRAAVDWIVSHQEGDGSWGGIQPPWVYSLIALSALGHPLDHPVLAKGLQGFRNEWSL
PSPDGAALRVQACLSPAWDTALAMRGLMDSGVSPDHPAIQRAAEWLVGKEVRYAGDWAVK
RPHLEPSGWAFGFDNVNYPDIDDSSVIVANLALTNLADRASDSAKEATIDRAVDWLTGMQ
SSNGGWAAFDYNNDSRSVTKIPFADFGEVLDPPSADITAHMLEMYGILGYSRWHPAVRRG
LHYLWQQQEPDGSWFGRWGVNYLYGTGAVLPALEALGVDMAQPAVRKAVQWLVDTQNPDG
GWGETCESYVDPTLSGQGDSTASQTAWALIALIAAGEAAGEPVTRGIEFLVATQQADGTW
DEPQFTGTGFPGYGHGDRPTKKGAPADSLQGAEMGAAFMINYHLYRNYFPLWALGRYLAA
VAPRVAQAVPLGRTETETDKSPNAIQEVIDLPTGPSRRARRQRSPMGSHRAVHRPTAPPP
>R9VYT6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAQAVFARGTAGVPSDDPRMQKAADWLLSKEVRHKGDWAMKVPNTEPGGWYFEFN
NEFYPDVDDTAQVLLALNKVDNPRERYQDQVARRAIDWEFAMQCRNGGWGSFDKDNTKMI
FQYVPFADHNAMLDPPTVDITGRMLEMLAAYGYTRDDKRVQKAIKFILDEQEPDGSWFGR
WGVNYIYGTFLVLRGLDAIGVCHNEPQMQQAAEWIRMVQNSDGGWGE
>R9W0C2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAQAVFPLGDTGVSRNDPRLPKAADWLLSKEVRHKGDWAMKVRNAEPGGWYFEFN
NEFYPDVDDTAQVLLALNKVDNPRERYQIQVAERAIEWEFAMQCRNGGWGSFDKDNTKMI
FQYVPFADHNAMLDPPTADITGRMLEMLASYGYTRADKRVQKAIDFIFEEQESDGSWFGR
WGVNYLYGTFLVLRGLEAIGVCQHEPQIQQAAEWIRMVQNPDGGWGE
>A0A4P6X7T6|squalene-hopene cyclase|EC 5.4.99.17|Sphingomonas sp. AAP5|TrEMBL
MTIETIDRASLVNEADATATRAAAALGALQRADGHWVFELEADATIPAEYVLLRHYLGEP
RDVEIERKIGNYLRRIQSASHHGWGLFHGGAFDVSASVKAYFALKMIGDAVDAPHMVQAR
AAIHKAGGAAAVNVFTRIQLALFDCADWRTVPTLPVELILLPRWFPVHLSKMSYWARTVI
VPLLVLAAKKPVARNVSGVRVDELYTHKRAPLESRAAGTKRAWTAFFNGLDVVLKAGEPL
WPKRTRRRAIRACLDFVTQRLNGEDGLGAIYPAMANSVMMLDCLGCPADDPMRAIARESV
ERLLVIKDDEAYCQPCVSPVWDTALAAHAMLEAGGDDAEARAMAGLAWLKPLQVLDVKGD
WAEEKPDVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRAKDRGGLPYDEPIARGVEWTVGL
QSKDGGWGAFDADNSYHYLNNIPFADHGALLDPPTSDVTARVVSMLAQLGETDSPRMKAA
LAFLEKEQMADGSWFGRWGVNYIYGTWSVLCALNAAGLDPKHPMVRKGADWLLHIQNLDG
GWGEDCESYALDYKGYTPAPSTASQTGWALLALMAAGKVDHPAVERGVRHLIATQAADGL
WGQEKYTGGGFPRVFYLRYHGYPAYFPLWAVARYRNLKRSNAGRPAFGM
>A0A533ZCN1|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
MKRLMNLITRLSGSLFSSVPDRLKGDARKRSTPALRLVSHNVHPTALPDQATRRAAGPLG
GQSESIDEAIRRSQAWLLGRQNLKDGFWVAELETDTTLTSEYLMLRRFLGLVDQERERKA
VRYLRSTQLPDGGWPIYHGGPSEISTSVKAYFALKLSGVPADEPFMVKAREAILAKGGVV
RASVFTKIALALFDQYDWRGIPCMPPEIMLLPKRFYFSIYAISYWSRTVLVPLLIMFEHR
PVCRISHEQGIEELFTQPRERIRYHEVPPLKKDRAWFTWHNLFITLDALLRLYDRMPVRR
LRERAVRKAADWTLQHVKGSGGIGAIYPAMANSVIALRCLGYELDHPVVVKALSEIEELE
VYDVVNDGQGLGETLHLQPCFSPIWDTSLLINALVEAGLPQDHPALLKAGDWLLSRQTTT
VGDWKIAAPDAEPGGWYFQFENELYPDVDDTAVVLMALGKLRMPDGAAQRQSIARGYRWV
MAMQGSDGGWGAYDKDNNRTVFNLIPFADHGALLDPSTADLAGRCLEMLGVLGYDRTHPA
AERALELSRRGREGRQYALPDRLGTARLPLGRGMGFHQRGAWGELFDPAPAAGRIMGGNP
ADRDRLPPRALPPLSFVLSVLPTLGARHVSEREDPRADEG
>A0A3M8ASR4|squalene-hopene cyclase|EC 5.4.99.17|Brevibacillus gelatini|TrEMBL
MREVGEEISRIQSVVLRSQQPDGSWRFCLESSPTTDAHMIILLRTLGIDDEQLMDGLTAR
ITDLQQENGAWKLYPDEAEGNLSTTVDCYYALLLSRRYEKNVPRMARARAFIRSKGGLGE
ANLLTKFATALAGQYKWPAHFLVPVEIALLPPRSPISFYDFVGYARVHLAPMMIVADRKY
VKATADTPDLSDLHVNPSVAPGVYPHRMLERFMRDGQNFLAAIHEHVVRLPFLPGLLHEL
SLRRLEQFMLARVEADGTLYNYSTSTFFMIFALLARGYSPRDPLIVKAMSGLRESLYETA
QGPHLQLATSAVWDTALLSHALQQSGLPASHPAIQRANRYLLQKQQLTFGDWKIRNPAGT
PGGWGFSHYNTMNPDIDDTTAALRALRSQSRLDKTAAAAWKRGLDWLLSMQNDDGGWPAF
EKNTDSPLISSLPIEGADTVSTDPSSVDLTGRTLEFLGRYAGYKESDAPVQKAIRWLLAQ
QEKDGSWYGRWGIAYLYGTWAALTGMMAVGVSPDHPAVQKAVDWLTRQQNADGGWGESCH
SDEKKTYVPLGASTPSQTAWALDALIAVHSRPTPAIERGVAYLSRQSQATGWTTSYPTGG
GRPGGTYFAYHSYRWIWPLIALSHYQRKYVSAS
>A0A533Z056|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
MQQRARQNARRLMRLVGGNPNLFSQAPAQPRWSESGYIPHQGATLNEAVRRAQAWLLSRQ
DEAGYWVHELEADTTLTSEYIMLRRFLGLVDLEKQRKAVRHLIEAQLSDGGWPIYHGGPP
DISASVKAYFALKLAGISAEEPFMQKAHSVILSKGGVVRANVFTKITLALFDQYDWRGLP
TMPAEIILLPPHTFFSLYALSYWSRAVLVPLLIIFNAKPVCRVSMEQGIAELYATPRKDV
NFRREPPFRKDQRWLTWQNAFITLDAALKVYDWLVPKGLRKKAIERAAEWMLERMAGEGG
LGAIYPAMANSVIALRCLGHETDDALFRKALGEIEALEVHAGDTLHLQPCFSPVWDTPLT
LSALIESGLPQDHAALVRAARWILARQCNKVGDWIVSSPNAKPGGWYFQFENEYYPDNDD
TAAVVIALSKIVTPEPDLQRIAMQRGAEWTLAMQSSDGGWGAYDKDNNKMLFNQIPFADH
RALLDPSTADLAGRELEMLGALGYGLSHPAAVRALRFLRKTQEENGSWYGRWGVNYIYGT
WSVLAGLKAIGEDMQAEYVRRAVIWLVSKQNPDGGWGESCLSYAEEEAHGVGLSTASQTA
WALIGLLCAGEMESLSVMRGVNYLLRHQDADGSWPEGMHTGTGFPRVFYLRYHGYSQYFP
LWALAMYRSLKSKGRSRADEIREHQRMHGHLRLEA
>A0A4R4DFQ8|squalene-hopene cyclase|EC 5.4.99.17|Paracraurococcus sp. NE82|TrEMBL
MQDLAAAAARPELTLADDGFGPSLRGTLDAAIGRATDHLLRRQQADGHWVFELEADATIP
SEYLMLRRFFGKRDPAQEERIGRYLRRVQAQEEANCSGGWPLFHGGPLDISCSVKAYFAL
RLIGDAPEAPHMQRARAAILAAGGAERSNVFTRSTLALFGQVPWHAVPVMPPEICLLPRW
FPFHLSKVSYWARTVIVPLTVVMARRPRPLAEIGVSLRELFVTPPEQVRRWPGGAHATEP
WKTAFAGLDWVLQRVQHLFPAGARARAEAMAEAFVTERLNGEDGLGAIYPAMANAIWMYH
CLGVPEDDPRVVTAWSAVEKLVLHRPDTDETYVQPCLSPIWDTALVSHALMETGDARAEA
AVTRGLSWLLDRQITDVAGDWAEARPGVLPGGWAFQYANPHYPDVDDTAVVVLALDRAQR
QLGNAGPQVARAVARATDWVVGMQSKGGGWGAFDADNTHHHLNSIPFADHGALLDPPTSD
VSGRCLAMLAQLGHGPENPAVQQAIDYMLAEQEPDGSWYGRWGVNYVYGTWSALTALNAA
GLPPEHPAMRKAVTWLKAHQNPDGGWGEDGFAYPRRGGTRADTDLRMGPSTASQTAWALL
ALMAAGAVEDEAVERGAAWLMRHQGRDGSWPEEDYTGTGFPRVFYLRYHGYARLFPLWAL
ARLRNLRRGNSRQVTHGL
>A0A8I1RV48|squalene-hopene cyclase|EC 5.4.99.17|Afipia sp|TrEMBL
MTLEDQKADAAPSAAAVDTSIAAASSALLGHRQSDGHWVFELEADATIPSEYVLLRHYLA
EPINRELEAKIGNYLRRIQNANGGWSLFYGHEFDMSASVKAYFALKMIGDSVDAPHMVRA
REIIRARGGAAKSNVFTRIMLALFGVVTWRAAPMMPVEIMLLPRWFPFHLTKISYWARTV
IVPLLVLMNKKPCARNPLGVGIDELFLEDPKSIGMTPKAPHQSQLWFTGFDILDRVLRVV
DPFFPKKSRQRAIDKAVEFVTERLNGVDGLGAIFPAMANTVMVYDLLGYPKDHPHYVLAR
QSVENLLVIKDDEAYCQPCVSPVWDTALTAHAMIEVGGEKEIESAKAALEWLKPKQVLDV
VGDWADKRPGVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRARGKLNVGEKYDEAIARGRE
WIDGLQSKDGGWAAFDADNLEYYLNNIPFSDHGALLDPPTEDVTARCVSMLAQLGETIEG
NPALARGVEYLRRTQLADGSWFGRWGVNYIYGTWSVLCALNAAGVPHDDPAIARATDWLI
SIQNPDGGWGEDGNSYRLEYKGYERSESTASQTAWATIALMAAGKVDHPATQRGIAYLIQ
NQTKDGLWTEPNYTGGGFPRVFYLRYHGYSKFFPLWALARYRNLRNTNSRFVGIGM
>A0A7K2PYH7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5470|TrEMBL
MTATTDGSTGALPPRAAAASETHLDTPVAAGIQEAAVRAVQRATEHLLARQDAEGWWKGD
LETNVTMDAEDLLLRQFLGIRDESTTRAAAKFIRGEQREDGTWAGFYGGPGELSTTVEAY
VALRLDGDAPDAPHMAKASAWIRAQGGIAAARVFTRIWLALFGWWKWEDLPELPPELIYF
PKWAPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHADPADPNPAKPLAPVASW
DGAFQRLDKAMHQLRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLQHPVMRAGLESLDRFAIWREDGSRMIEACQSPVWDTCLATIALVDAGVPADHPQL
VKAADWMLGEEIVRPGDWSVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHDP
DRVENAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLSHDPRTRRGIEWLLAEQEPDGSWFGRWGVNYIYGTGSVVPALTAAGLPASHP
AIRRAVAWLEKVQNDDGGWGEDLRSYKYVKEWSGRGASTASQTAWALMALLAAGERDSKA
VERGVEWLASTQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFSRT
EAL
>A0A0H2Y240|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cenocepacia (strain AU 1054)|TrEMBL
MIRRMNKSAPSSWSALDAAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDR
IDDVRQEKMARYLRANQRLDTHGAWDLYVDGAPDVSCSVKAYFALKAAGDSEHAPHMIRA
RDAILKLGGAARSNVFTRILLATFGQVPWRAAPFMPVEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNVSIRELFVTPPEQERHYFPPARGMRRLFLALDRTIRPIEPL
LPKRLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMQVLGYPDDHPLRRDCENAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVAAPETGDTASGALRDLDGRIARA
YDWLATRQVNDLCGDWIENAPADVEPGGWAFQYANPYYPDIDDTALVTAMLDRRGRTHRA
ADGTHPYASRVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVS
GRVLLCFGVTKRAADRASLARAIDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALAGE
DKSQPYITRALDWLRARQHADGGWGETNDSYLDPKLAGTNGGESTSNCTAWALLAQMAFG
DCESDSVKRGIAYLQSVQQEDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRL
AGAKDAGATRSCASGASAAPATDDALA
>A0A8J7QAT9|squalene-hopene cyclase|EC 5.4.99.17|Sciscionella sp|TrEMBL
MSIAISDSEQTDSPLFGKLSATVHKAREFLLSIQQEEGWWKGELETNVTMDAEDLLLRQF
LGISDPAITAPAANWIRSQQRKDGTWANFYGGPADLSTTTEAYVALKLAGDDIDAEHMRK
ARKYILDSGGVEKTRVFTRIWLALFGEWAWDDLPILPPEMIFLPSWFPLNIYDWGCWARQ
TVVALTVVCAFRPVHELGFDIDELRTGAKKPAMRSVLSVSGVFERLDWLLHQHEKLPVKP
LRQWALRKAGEWIIQRQEADGGWGGIQPPWVYSILALRLLGYPLEHQAVRKALDGLDGFT
IVEDRPHGTVRRLEACQSPVWDTGLAITALLDGGVAADHPGVLRAANWLLKEEIRVTGDW
AVRRPKLEPGGWAFEFANDIYPDTDDTAEVLLGLRRVAHDDPRRWQAAKKRAVNWLIGMQ
SADGGWGAFDADNTRTLCEKLPFCDFGAVIDPPSADVTAHIVEVLAAHDKTETGSGGQRA
IERGVRWLLRHQEADGSWFGRWGANHVYGIGAVLPALIAAGIAPQEQPIRRAVDWLAEHA
NRDGGWGEDLRSYIDPAWIGRGASTPSQTAWALLALHAAGERGDVVDGGVRWLVDHQRAD
GSWDEPYFTGTGFPGDFYINYHLYRIVFPLSALGRIHRDGLLE
>A0A538I829|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MTAIRELTALDVVLERGTERLFELQHPDGWWKGELESNATMIAQHLFWHHVLGLRTRELD
RKIANELLARRRDDGTWAIWFEGPGDLDTTIEAYVALKLCGVDPGPQSRSFIQRHGGVAR
ARIFTKCFLALLGQWPWQRIPPVPIELILLPPEAPFSIYDFSCWARGTFVSLAGTMALRP
VRPADVDLREIGARPGESRAAPRPGRRRREALGVAERWVRVRQEADGSWGGIQPPWVWSI
LMLAALGNSWEDQTLRRAVEGWDGFTIDEGDRLRPEACQSPVWDTALAVLALRAAGVPAD
DERLQAAGRWLLREEVRVRGDWAIRAPDLEPGGWAFEFENDRYPDVDDTAVVALALRELG
IGDEAVRRGLDWTVGMQSAAGGWGAFDLNNSAMWLYRIPFCDFGKVTDEPTADVTAHALE
VLGPEAGYETAVAAGIDWLLVEQERAGSWFGRWGVNYLYGTGAALPGLAACGIPPEHPAM
RRATAWLDSVQQPSGAFGEDIRSYADADWRGRGAATASQTAWALLGYVAAGEAGRSSARR
AADYLCRIQRADGDWDEQQFTGTGFPLDFMIRYHLYRLTFPLLALGRLRERLSA
>A0A525VU65|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp. CG24C|TrEMBL
MKLIRALLDRLSDSLFVSVPEKLGLATELSNVPPLRLVSDKSIPSASVDASTRRSTSHSI
SQVDVLDDAVRRSQAWFLSRQHASEGYWVAELEADTTLTAEYLMLRRFLDRVDPDRERKA
VRYLRAMQLPDGGWPIFYGGPSEISASVKAYFALKLSGISADEPFMVRAKDCILAKGGVV
QTNVFTKITLALFDQYDWEGVPHMPVELMLLPKGFYFNIYAISYWSRAVLTPLLIIFAHR
PVCQIPRQQGIDELYFIPRKEIRYWKFPPFNKDQKWFTPHNFFVALDAILKLYDRMPLMW
LREKALHRAATWMLEHIKGSGGLGSIYPAMANSVMALQCLGYQVDDPLVRKALHEIESLE
VYGTVSIGEQRLEALHLQPCDSPVWDTALLMNALIETGMPQDHPSLQKAAAYLVSRQTKT
VGDWKVSSPDAEPGGWYFQSENEFYPDVDDSAVVLMALSKVRMAQTAELQDSIRRGANWV
LAMQGSDGGWGAYDKDNNRIVFNYIPFADHHALLDPSTSDLTGRCLEMLAALGYDQTHPA
VAPALRFLKREQEPDGSWYGRWGVNYIYGTWSVLAGLRAIGVDLSEPYIRRAVAWLESKQ
NPDGGWGESCLSYGDDPAWSGKGDSTPSQTAWAIMGLMSAGMTDAFSVARGVQYLLRQQM
KDGSWEEVRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRTRGKMRADEVRQQVLASG
CHRADR
>A0A410UKJ0|squalene-hopene cyclase|EC 5.4.99.17|Dyella sp. M7H15-1|TrEMBL
MNASTPNAAAVNDLFQTAETSGLNAAIERGRAALLARQHQDGHWCFELESDATITAEYIL
MMHFMDDIDDVLQEKMARYLRDTQVKHTHGGWSQYHGGDIDLSCTVKAYFALKATGDDPE
AEHMRIARKAVLALGGAAKANVFTRILLALFQQVPWRATPYVPVEIMLLPRWFPFHIEKM
SYWARTTLVPLTILCSLKAKAANPRKIHIRELFVIPPDQEHRYFIRGGLLNRTFLALDKI
GRCADPLIPKKLRQRAIDKAVAWFLPRMNGEDGIGAIFPPMVNCLEVLKLLDYPKDHPVR
QTCLRSIQKLVVHRDDGSAYCQPCVSPIWDTLWSALALMHTSDDAVTQDAIARSTDWLAS
KQEFELKGDWAAQAPSLPPGGWAFQYNNAYYPDIDDTAVAAALLHIQDRRRGESGRHRVN
TDRAADWMIGLQSKNGGFAAFDANNTHYRLNAIPFADHGALLDPPTEDVSGRVVAALGVL
ARPQDQESLRRAIDYLRATQLEDGSWWGRWGSNYIYGTWSVLAGLALAGEDPRQAYLRKA
IAWLRSRQNTDGGWGETNDSYIDAALRGTQHGVSTPQTTAWALLAQLAMGETQSDSVERG
IAFLLANQQTRGTLEGLWYHPSHNAPGFPRVYYLKYHGYTAYFPLWALARYRQLTQSAVA
>A0A2U3K961|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Sulfotelmatobacter kueseliae|TrEMBL
MDKDSPDSKVASAAAGSNPQLRFGKIEELASRVGSAVAAARKYLFSQQHEQGYWCGELEA
DTTLESDYILLHKLLGTGTEERFQKAANWILRHQNEDGGWSIYAGGPSNTSASVKAYFGL
KLAGYTADHPALQRAKKKILEMGGVTEVNTFTKIYLCFFGQYDYDAVPAIPPEIVLFPNW
FWFNIYEISSWSRAILVPLSICYAKKPFKKIPREMGVEELFVGGMQKSRMHLHWAKKLIS
WRNFFLVIDRITHWLERVHVRPLRSIALKHAEKWMLARFEMSDGLGAIYPSMLNAIIALR
CLGYSLDDPQVIRALDEFEKLGIEEEDTFRMQPCMSPVWDTAYALFALGEAGVPADDPRL
VKCADWILQKQVRNVGDWKIKNKKGQPGGWYFEFNNEHYPDVDDSAMVCLALSRVEHPNG
RYQRESVQRAIDWIFSMQCKNGGWASFDKDNDRMIFQYIPFADHNAMLDPPTVDITGRIL
EMLATYGYDQNHPAVKRAIQFVRQEQQPDGSWFGRWGVNYIYGTALVLRGLEAIGMDLHE
PCIQQGAEWLRMVQNPDGGWGETVGSYDDPSLCGQGDSTPSQTAWAILGLLAANDTRSDS
VARGIAYLLRTQKKDGSWDEEYFTGTGFPRVFYLMYHLYREYFPLLALTTYAKVMEKQS
>A0A088UL90|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cenocepacia|TrEMBL
MIRRMNPSTPFSRSALDAAVARGRDALARLQQPDGSWCFELESDATITAEYILMMHFMDR
IDDARQEKMARYLRAIQRLDTHGGWDLYVDGAPDVSCSVKAYFALKAAGDDEHAPHMVRA
REAILKLGGAARSNVFTRILLATFGQVPWRATPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLALCSLKARARNPRNITIRELFVTPPDDERHYFPPARGMRRAFLMLDRAVRHLEPL
LPKRLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYANQMMQVLGYPDDHPLRRDCDRAL
EKLLVTRPDGSVYCQPCLSPVWDTAWSTMALEQARGVAAPESGEDAEAAQSLDARIARAY
DWLAQRQVDDLRGDWIENAHPDTQPGGWAFQYANPYYPDIDDSAVVTAMLDRRGRTHRNA
DGSHPYAQRVARALDWMRGLQSRNGGFAAFDADCDRLYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRADDRAALARCIDYVKRTQQADGSWWGRWGTNYIYGTWSVLAGLALAGED
PSQPYIARALAWLRARQHADGGWGETNDSYLDPRLAGTNGGESTSNCTAWALLAQMAFGD
CESDSVRRGVAYLLSVQQDDGFWWHRSHNAPGFPRIYYLKYHGYTAYFPLWALARYRRLA
GAAASSGSSAPSAGETLPAVA
>A0A836X048|squalene-hopene cyclase|EC 5.4.99.17|Nitrospinaceae bacterium|TrEMBL
MNFDERLDLAINKSRNFMLSRQTEEGYWVDELESNATITAELVFFMHFTETVDLEKQKKI
TNYLLHTQREDGSWPLYFGGPCDINSTVESYMALRLAGVSKGRPEMIQAREAIFANGGIK
ATRVFTKVFLAMFGQISWSVCPSVPVEIILLKNWFPLNIYEMSSWSRGTVVPLSIVISHK
PVCHLPKGNDFKELFTSGDSELGFESDGLVFSSWRNFFINLDKVIKFIGRSPWKPFRKIA
LKRALSWVIEHQEEQGDFSGIQPAMLNSLLAYHYEGISKNDPKWVKGLEAVERFLINKKE
GTLMQACVSPLWDTAIAANALCDSGMSTDHPALVKAAKWILSKQVVKKGDWAIKNPKVEP
GGWAFEFYNELYPDCDDTAEILIFLNRITLPDSYQKLQESRKATSWLLSMQCQSGGWAAF
DINNEQEILNQVPFADHGAMLDQPSADVSGRVLWLLGQLGFKNNHPKVKRVINFLKAKQE
SNGSWWGRWGVNYIYGSWLALTGLASIGEDMSQPYVCRSMKWFEDHQNKDGGWGETCESY
KIPSLAGKGNSTVSQTAWAVMGMIAGGEEESLVVKRGIEFLLNKQEPHGSWQEDEFTGTG
FPIHFFIKYHMYQHFFPLMALGRYRSVLKP
>A0A5C8HGL7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces lavendulae|TrEMBL
MTATTDGSTGATLPSRAAAASDTTLTTPEAAGVPEAAARAARRATDFLLARQDAEGWWKG
DLETNVTMDAEDLLLRQFLGIQEERTTQAAAKFIRGEQREDGTWATFWGGPGELSTTIEA
YVALRLAGDAPDDPHMARAAAWIRERGGIASARVFTRIWLALFGWWKWEDLPEMPPELIW
FPGWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPANPNPPKPLAPANT
WDGAFQRLDRALQQLRKVVPRRLRRAAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVLREGLASLDRFAVWREDGARMIEACQSPVWDTCLAAIALVDAGLPADHPQ
LVKAADWLLGEEIVRPGDWAVKRPQLPPGGWAFEFHNDNYPDIDDTAEVSLALRRIRHHD
PERTDRAIGRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAAEGLAHDPRTRRGIAWLLAEQEQNGAWFGRWGVNYIYGTGSVVPALTAAGMPVAH
PAIRRAVTWLESVQNDDGGWGEDLRSYKHVREWAGRGASTPSQTAWALMALLAAGEKDSP
AVERGVQWLAATQREDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFER
QLLARTPRPRTAAAKPAGSPLAEAKGS
>A0A385D6X7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces koyangensis|TrEMBL
MTATTNGPAGAAPSRPAPARTTATTTDSTVLDAAAVEAAAERARARAADHLLGLQSPEGW
WKGDLDTNVTMDAEDLLLRQFLGIRDEATTRAAALFIRGEQREEGTWATFHGGPPDLSTT
VEAYVALRLAGDSPDAPHMTRAAHWVRSQGGIAEARVFTRIWLALFGWWPWDRLPELPPE
LIFLPPWAPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPADPAPRARFAP
LASWNGAFQRLDRALHAYRKIAPRALRRAAMATAGRWIVERQENDGCWGGIQPPAVYSMI
ALHLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALADAGVPAD
HPQLIRAADWMLDEQIERPGDWSVRRPHLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVR
HPDTARMERAISLGVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDPPSADVT
AHVVEMLAAEGLAADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALIDAGLP
TTHPAIRRAVAWLESVQNDDGGWGEDLRSYREQGRMARGASTASQTGWALMALLAAGERE
SRAARRGVTFLADTQHEDGSWDEPYYTGTGFPWDFSINYHLYRQVFPLTALGRYTRGAAP
EGA
>A0A3M9XWH6|squalene-hopene cyclase|EC 5.4.99.17|Methylocystis hirsuta|TrEMBL
MNAAARIDADYTAVSSEALETSIQNAKRALLSLGKGDGHFCFELEADTSLSAEYVLMRHF
RAEPVDAELERKIAVYLRRCQGDHGGWPLYQDGPFHISSSVKAYFALKMIGEDIDAPHMA
RARAAILAYGGAAKSNVFTRALLALYGEIPWRGVPVMPVEIMLLPKWFPFHLDKISYWGR
TVLVPLLVLMTKKPRAKNPRNIHIAELFTTPPEEVKVWPKGEHQTWPWANIFGQIDKLLR
LIEPHMPSGPRERSIELAMTWTTERLNGVDGLGGIFPSMVNSLLMYDVLGAPDADERKKQ
AREAIERLLVATDTEVYCQPCVSPVWDTCLTAHTLLETGDEDAREQARQACEWLAPLQVL
DVKGDWAAQRPDVRPGGWAFQYANAYYPDVDDTAVVVTAMDRLTANDASRPYDERIARAK
EWIVGMQSKNGGWGAFDADNTCHYLNHIPFADHGALLDPPTADVSARCVSMLAQLGDTIE
SSECLKRGVDYLLKEQEKDGSWFGRWGANYIYGTWSTLCALNAVGLPHEHDAYRRAVAWL
TAIQNDDGGWGEDLSSYKLDYKGYEKAPSTASQTAWALLGLMAAGDVDHPAVARGIAYLQ
STQNGAGLWNEARFTATGFPRVFYLRYHGYGKFFPLWALARYRNLKRANSKRVQIGL
>A0A8J7HL59|squalene-hopene cyclase|EC 5.4.99.17|Atlanticothrix silvestris CENA357|TrEMBL
MQTQDRVTVNKVAAAIAGSQQYLLSTQYPAGYWWAELESNVTITAEVVLLHKIWGTDQAR
PLHKVAAYLRSQQRQHGGWELFYDDGGELSTSVEAYMALKLLGVSVNNPAMIKARDFILQ
RGGISKTRIFTKLHLALIGCYDWRGIPSLPPWVMLLPPAFPFNIYEMSSWARSSTVPLLI
VCDRKPVFITEPTINLDELYAEGVDQVRYELPRAGNWTDLFLTLDQGFKLAESLNLVPFR
NEGIKAAEKWILERQEVTGDWGGIIPAMLNSMLALRCLGYSANDPIVERGLQAIDNFAIE
TEDSYRVQPCVSPVWDTAWVMRALVESGLAPDHPAIVQAGEWLLQKQILDYGDWIVKNRQ
GKPGAWAFEFDNRFYPDVDDSAVVVMALHVAKLPNEKLKQAAIARALNWIASMQCKPGGW
AAFDLDNDQDWLNSVPYGDLKAMIDPNTADVTARVLEMLGACNLPIDDQKLERALVYLLS
EQETEGCWFGRWGVNYIYGTNGVLSALALIEPQKHQVNIERGATWLIKCQNSDGGWGETC
RSYDDPRLKGQGRSTASQTAWALIGLIAAGEATGKLAREAIERGISYLLTTQKPDGTWYE
ADFTGTGFPSHFYLKYHLYQQYFPLIALGRYQELQQRSSS
>A0A845U8A8|squalene-hopene cyclase|EC 5.4.99.17|Acidithiobacillus ferrianus|TrEMBL
MNRILQPMRTGPGVFRSSLERVVAAARAALEGMQAADGHWCFEFEADCTIPAEYILMQHY
MDERDPRLEAKMAVYLRGKQADHGGWPLYYGGRFDLSASVKAYYALKLAGDDRDLPHMRR
ARETILAHGGAERANVFTRITLALFQQVPWRAVPFIPVEIMLLPRWFPFHIYKVASWSRT
VMVPLFILCSLKARAKNPLQVHIRELFRRPPEQISDYLSHARQGTVARLFLLLDRFWRHM
EAWIPPRIRHRALRKAEAWFTARLNGEDGLNGIFPAMVNAHEALELLGYPADHPYRRQTG
AALRKLVVERAADAYCQPCVSPVWDTCLALHALLEQEEEVTPAIEKGIQWLKDRQIGQEP
GDWREQRPQLAGGGWAFQYANPYYPDLDDTAAVGWALAKARREEDRDSIEKAANWLAGMQ
SSNGGFAAYDVDNTRYYLNEIPFADHKALLDPPTADVTGRVVAFLGHLGRPRDRDVLRRA
VAYLLREQEPSGAWFGRWGTNYIYGTWSVLMALAELKDTSLQPAMDRAAAWLRAVQQKDG
GWGENNDSYADPGQAGCGQASTAAQTAWACLGLMAAGDRDSTALHRGITWLQAHQEKNGH
WWDPFFNAPGFPKVFYLIYHGYSLYFPLWALARHRNLGCIHRD
>A0A6I1FDN1|squalene-hopene cyclase|EC 5.4.99.17|Bacillus aerolatus|TrEMBL
MKHHTEELVRQIIRQLKESQTPDGSWDYPFETGISTDAYMIILLRTLEINDEDLIRELTE
RIWRKQEKNGAWKLFHDEEHGNISATVEAYYSLLYSGYYTKKDKRLQAAKKFILASGGIE
QSHMFTKIMLSLTGQYPWPPFFPIPVEMLLLPLSFPVNFYDFSVYGRANLAPIMIAANKK
YSKKTKKSPNLSGLFVSRADDFFNWPETRESKSFFSLIGQGIQQLVGLPQYIHSLAIHRA
KQYMLDHIEPDGTLYSYFSSTFLMIFALLSLGHSKSDPVILKAVSGLKAMKCTINGRSHM
QYTTASVWNTSLISYALQQAGVSPSDPMVTKANRYLLERQQYKYGDWTFHNPGVLPGGWG
FSHINTMNPDVDDTTASLRSFSPLVQTDPHLRQAWDRGTQWIFSMQNNDGGWPAFEKNVD
KRLLNLLPIEGGKFLLTDPSSADLTGRTLEFLGGYTKLPKNHEVMKRGIDWLFHHQKKDG
SWYGRWGICYIYGTWAAITGLMASGVKAQNPVIRKAVNWLHQIQNQDGGWGESCKSDIKN
TYIPLGSSTLTHTSWALDALISTAEKPTPEIQAGISYLLKSYNKNDWTLSYPAGQGMGGG
FYIHYHSYQYIFPLLALAHYERKF
>A0A7X2L1C6|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus monticola|TrEMBL
MGNVLSAVDEAIDQLTATLIQQQQHNGTWHFCFENGIIIDAYVIILFRTLNIQNEVLIRQ
LHDRILTEQQPEGCWKLYFDEEEGNLSASIEAYYALLYSGYSQKTDEPMLRAKRFIQSKG
GLGQVSSILTKVILAATGQMKWPASLSSIPLEVLLLPTFSPINFFEFSGYSRIHLTPILI
MADHHFSIKTAHTPELDELKVDRIHINEPHSREDQEVLDSINSGLRKLIGTPRSIHEAAI
TKAEQFILQRLEADGTLYSYASSTILMIFALLALGYDKDHPLITHAVQGITAMQYNFNDK
TTIQNSPSTVWDTALLAYTLQEAGINADHVAIRNAAAYLLSKQQDKTADWSIHNPNPIPG
GWGFSDSNTLNPDVDDTTAALRAIQTLSQTDPLHRESWNRGLNWVLSMQNEGGGWPAFEK
KTKKMLTWLAIDGAKSAAIDPSEADLTGRTLEYLGNFCGLDIRHEFIKYGTKWLIKHQEK
DGSWYGRWGICYIYGTWAALTGLEAVGVSSNHITVQKGTQWLLRIQNPDGGWGESCRSDR
LLRYVPLGESTPPQTAWALDALIAVHPQPTAQINKGIYRLIASLQEDNWMISYPTGAGLP
GNYYTHYHSYRYIWPLLTLSHYREKYRH
>A0A8D3WGP3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces pratensis (strain ATCC 33331 / IAF-45CD)|TrEMBL
MTATTDGSTGAANLRAAAASDPTESTSAAPDMMAVARHAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETVKAAARFIRGEQLGDGTWNTFYEGPPDLSATVEAY
VALRLAGDRPDDPHMIRAAGWVREQGGIAESRVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPACPNPSRPTAPAASW
DGVFQRLDKALHLYHKVAPRRLRRIAMNEAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVSPDHPAL
VRAADWMLGEEIVRPGDWAVRKPGLAPGGWAFEFHNVNYPDIDDTAEVALALRRVRHPDP
ARVDAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGRAHDPRTRRGVEWLLAEQEASGAWFGRWGVNYIYGTGSVVPALIAAGLPAAHP
SVRRAVDWLRSVQNDDGGWGEDLRSYREEKWIGHGSSTASQTGWALLALLAAGERETRSV
ERGVAWLAATQQADGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFATAT
AIGAGTGKGA
>A0A653RX81|squalene-hopene cyclase|EC 5.4.99.17|Bacillus altitudinis|TrEMBL
MQDFKTRVNEYIDELHMQVERRQREDGAFIFCFEGPMMTNAFFIMLLKAVGDPDQQLIHQ
LAEAIHAKQNEDGSFSLYHDQSGHLTATVQGYCGMLASGRFQKDEPHMEKAAQYIRSKGG
LKSVHFMTKWMLAVNGMHPWPYFYAPLSLLLIPTSFPLHFYHLSAYARIHFVPMMIALNK
RYTSHATFPSLAHLDENMSKNPFDWFMAREERSTDHFLMYMRSYTALDSRLDFFGYEAAK
RYMFDRLEKDGTLYSYLSATIFMVYALMSLGYSPGHHLIQKAVRGMKRLVTSCQGKLYAE
NSTSTVWDTALVSYASQRAGRKREDPMIMNSFNYLLDRQQMKKADWAVHNRHAAPGGFGF
SHINTNNPDCDDTQIVLKAIPKEYAPLQWKRGYDWLLSMQNRDGGFSAFEKNQDHFLLRH
LPLESAEDAAIDPSTPDITGRVLHLIGLEERDTASPSILRQKDRCVKWLIDHQEKNGSWF
GRWGVCYIYGTWAALTGLKAAGVPSSHPAVQKACRFLKQIQLEDGSFGESCKSAELKTYV
PLPFGTVVQTAWATEALLQYEKANNAAILKAVSFLVNHHHTEEAMYYPVGIGLPKQFYIT
YHSYPFVFPMMACSTFLDEMRRIHE
>A0A7W1YZ17|squalene-hopene cyclase|EC 5.4.99.17|Chthoniobacterales bacterium|TrEMBL
MFNPSANIIALPRTRPEENAPPLATNEDLAEAISLAQGNLLRQQKPDGHWVGELMVDSTL
CSDYVLFMHWLGEVDDTLQRRCAKHILKRQLPDGGWNIYYGGPSEINACVKAYFALKLAG
HSIDAPFMQEARANIVRLGGIPRMNTYSKLYLALLGQFPWKYLPAIPVEMVLLPNWCFFN
IYKMSSWSRAMLTPLAIINHFKPTRELAEDKQLHELYPVGTEGSDFTLSRDQRLLTWRNF
FLRADRALKMLEPMHSRSLRQRALEEAERWMVERTGDGSDGLAAVFPAMLNSIIALRALS
YPKEHPLYQKALKDFRGLFVDDADDFRIQPCLSPVWDTAINIIALAESGFPAQHPALQQA
ARWLIDKEVRQRCDWTANNSHPEASGWAFEYNNVFYPDTDDTAMVLMALRLVRPNEQPEL
ATLFKRALAWQLSFQCADGGWAAFDKDVTRHWLEDMPFADHNAILDPTCSDLTARTLELL
GYIGFDPGRPLVRKAIRYLRETQEDDGSWYGRWGVNYIYGTWQVLRGLCAIGEDMTEDWI
LRGRDWLESCQNDDGGWGETCASYENPDLKGQGASTASQTSWALMGICACGDLDRPSVQR
GLRYLLTTQRHDGAWDEPEITGTGFPGVFYLKYDMYRQNFPLLALATYVNYRGGIGHYQS
FYRWAGR
>A0A7X4AW09|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
MIEQGMENRLREALERTQRYFFRTQHEDGYWWGELESNPTMEAEYIMLTHFLGSEEEDRI
PRIAEDIRRRQSADGSWRMYYGAPGDLSTSIECYFALKLAGDPPEAPHMAKARTFILACG
GVPKARVFTKIWLALFGQWDWKGTPAMPPDMMLLPRWAPFNIYRFASWARATIVPMTIIL
TLHPTRPPHESAWVTELYPEGPVTFTLSRWKAKPFSLKGWFLVLDRAIRIYRKLPFIPGR
KRAIKAAVDWIVRHQEADGSWAGIQPPWVYSLIALSAIGFPLDDPVISKGLEGFRRNWSV
PSEDGDALRVQACLSPVWDTCLAMRGLFDSGVPANHPAIRGAAAWLIQEEIRVKGDWAVY
RPHLEPSGWAFEFDNVHYPDIDDSAIVVTDLAATRMRDDTGERARTEALDRAVNWLTGMQ
CSNGGWAAFDWNNDSRELAKIPFADFGELLDPPSVDVTAHVLEMYAKLGYTVEHPAVRRG
LSYIWEQQEHDGPWFGRWGVNYIYGTGAVLPALEALGLDMRQPRVRRAVKWLLARQNPDG
GWGETCVSYADPSLRGQGESTPSQTSWALMALIAAGEAGHEYVARGVEFLLERQQEDGTW
DEPQFTGCGFPGYGPGERPNEYEPLDGPNSQGPELGAAFMIKYHLYRNYFPLSALGRYAQ
SLHP
>A0A5M8T2Q7|squalene-hopene cyclase|EC 5.4.99.17|Acidobacteria bacterium AB60|TrEMBL
MSNPQGIKQTATPRFGRLDADLAEVEAAISRSSEHLLSRQHPEGYWSGELEADAMLEADY
IFLHTLLESGDPGRLKRAFAEMMRYQKEDGSWSLYPGGPGNISLSVKCYFSAKLMGLKAD
DPRMAKCRAWILAHGGVVACNTFTKMYLCALGQYDYDAVPAIPPEIVLFPNWFYFNIYEI
SSWSRSILVPLAIIYAKKPFKKIPPEQGIDELFVGGRENSVLRLRMDRENPLSWRNFFLV
CDRITHWFEAVHIRPLRRLALKRAEKWMLERLEMTDGLGAIYPAMMNAIIALRCLGYSED
DPQVIRARDEFEKLGIEEAASEAMPEPTFRMQPCMSPVWDTAQALYALGEAGVPRNDPRM
VKAADWLLSKEVRHKGDWAVKVPNTEPGGWYFEFNNEFYPDTDDTAQVLLALNKVDHPKE
RYQHQVAERAIAWEFAMQCRNGGWGSFDKDNTKMIFQYIPFADHNAMLDPPTVDITGRML
EMLSAYGYSRGDKRIERAIQFILSEQEPDGSWFGRWGVNYIYGTFLVLRGLDAIGFDHNE
PQIQQAAEWIRMVQNSDGGWGETCGSYDDPNTRGEGPSTPSQTAWALLGLLAAGDDRSDS
IAKGVRWLLERQQDDGSWDESMGEGAKRESIITGTGFPKVFYLAYTLYRQYFPLMALTAY
RRAMEKQLLAVSS
>A0A370AYD6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces corynorhini|TrEMBL
MTATTDGSTGAVGPRAPSGNGTTETTVPPGGDPIRVAAERATARSVEHLLGRQDAQGWWK
GDLATNVAMDAEDLLLRQFLGVQDARTTHDAGLFIRGEQRADGTWATFHGGPGDLSATVE
AYVALRLAGDRPDDPHMARASQWVREHGGIARSRVFTRIWLALFGWWKWDDLPELPPELV
FLPKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELAGPPQAGGRAARQAPLA
SWDGVFQRLDRALHVYHRLAPRRLRTSAMNAAARWIIERQENDGCWGGIQPPAVYSVIAL
HLLGYDLDHPVMRAGLESLDRFAVRRADGARMIEACQSPVWDTCLATIALADAGLSPDHP
ALVKAADWMLGEQIARPGDWEVRRPGLTPGGWAFEFHNDNYPDIDDTAEVILALRRVAHP
DRRRMDAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAYEGKAHHPDTRRGIEWLLAEQETFGGWFGRWGVNYVYGTGSVVPALTAAGLPTS
HPAIRRAVSWLESVQNEDGGWGEDLRSYRDEAWIGHGATTASQTAWALLALLAAGERESK
AVERGVAWLAETQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPKAL
TALAGTRKGS
>A0A6N9UDW5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces coelicoflavus|TrEMBL
MTATTDGSTGASLRPLAASASDTATDTDITIPAAAAGVPEAAARATRRATDFLLSKQDAQ
GWWKGDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELS
TTIEAYVALRLAGDSPDAPHMARAAEWIRSRGGIASARVFTRIWLALFGWWKWDDLPELP
PELIYFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPVRPNPPRPL
APAASWDGAFQRIDKALHAYRKVAPRRLRKAAMNSAARWIIERQENDGCWGGIQPPAVYS
VIALYLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVP
EDHPQLVKASDWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRR
VRHHDPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSAD
VTAHVVEMLAVEGLAHDPRTRRGIQWLLDAQEADGSWFGRWGVNYVYGTGSVIPALTAAG
LPTSHPAIRRAVRWLESVQNEDGGWGEDLRSYRYVREWSGRGASTASQTGWALMALLAAG
ERDSKAVERGVEWLAATQREDGSWDEPYFTGTGFPWDFSINYNLYRQVFPLTALGRYVHG
EPFAKKSRAAEALTESAPAEVKGS
>A0A5D0NEG8|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura chibensis|TrEMBL
MTATEQTPDTSESTAPRTAANALDAAREHLLLLQSPQGWWKGELQTNVTMDAEDMLLREF
LGIRTEDDTREAARWIRSQQAADGAWANFHDGPPDLSTTVEAYVALRLAGDPPDADHMLR
AAAHVRSAGGIPATRVFTRFWLAMFGRWPWDELPVVPPEMIFLPRWFPLNVYDFACWARQ
TIVPLTVVAALRPVRPLPFALDELYPGYDAPRPRARVRPGWDMAFQTLDRALRGYERRPV
KGLRRAALRRAAEWIVARQERDGSWGGIQPPWVYSLLALHLLGYGVDHPVIQRGLDGLER
FTIRDDRGRRLEACQSPVWDTVLAMTALSDAGLPAGHPALERAAGWVIGEEVRGPGDWSV
RRPGLPPGGWAFEFDNDVYPDVDDTAEAVIALNRVRHPLAEPAIERGVRWMAGMASKDGG
FAAFDADNTRALCRRLPFCDFGEVIDPPSADVTAHVVEAMAHRGMADSLLVKRAVVWLLK
AQEPDGSWFGRWGANHVYGTGSVVPALVAAGVRPDKPAIRDAVGWLERHQRDDGGWGEDL
RSYRDRSWVGHGASTASQTAWALLALLAAGERGEATERGVRWLVDHQRPDGTWDEDHFTG
TGFPGDFYINYHLYRLVFPLSALGRYLKGS
>A0A841JV45|squalene-hopene cyclase|EC 5.4.99.17|Silvibacterium bohemicum|TrEMBL
MSTTFDTPQPGAPDHPVSPQSVGSKSRSAASNAGTPGHVAENDTPRENGRVRFGRIDADL
QDVEAAAHRSRDYIFSQQDPAGFWCGELEADPLLEADYIFAHELLGTRAGNEDKLQRAMT
EIWRYQNADGGWSIYPGGPSNISLTVKCYFAGKLMRISPDRPDMSRARDWILAHGGVVEC
NTFTKIYLCFLGQYEYDAVPAVPPEIVLFPNWFYFNIYEISSWSRAILVPLSIAYAKKPF
KKIPTEQGIDELFVGGRTNADLHLRFDRKNKISWRNFFLLVDRIVHWMERIHIRPLRKIA
LKKAEKWMLERFEMSDGLGAIYPAMLNSIIAMRCLGYSLDDPQVIRAMDEFEKLGIDAPN
GTKDYPQPTFRMQPCVSPVWDTAQAVYALGEAGVPRNDARLLKAADWMLSKEVRHKGDWS
VKVPRVEPGGWYFEFNNEFYPDVDDSGQVLLALNKVDNPRERYQYDVSQRAIDWIFSMQC
KNGGWASFDKDNTKMIFQYIPFADHNAMLDPPTVDITGRILEALATYGFTRKDKRIERAI
KFVYDEQEPDGSWFGRWGVNYIYGTFLVLRGLEAIGVWNHEPQIQQAAEWIRSVQNADGG
WGESCNSYDDPVTRGIGLSTPSQTAWAVLGLLAAGDKRSDSVAKGIKWLLKYQQPDGSWD
ESVGSGPQRQAIYTGTGFPRVFYLAYHLYRDYFPLLALTNYKRALEKD
>A0A369TH72|squalene-hopene cyclase|EC 5.4.99.17|Ferruginivarius sediminum|TrEMBL
MRFKASDSVAESADGGNAGSAKSESDRLGAVDALIRRAGAALRERQQPDGHWVFEFEADA
TIPAEYILLRHFLGEPDAGKEAKTGRYLRRIQRDDGGWPLFEDGAADVSATVKAYYALKL
IGDDPEASHMARARAHVLKRGGAARANVFTRITLALFEQVPWRAVPTMPAEIMLLPRWFP
FHLEKVSYWSRTVIAPLAVLMSLKPKARNPRGVNIRELFVTPPEKERDYIDNPTGGTVGS
VFVGLDKAVKVIDSHMPGAVRRRAIDAAMDFIKPRLNGEDGLGGIFPAMANAVMAFDALG
YPPDDPDVATARAAVEKLLLDRGDELYCQPCLSPVWDTSLAIHAMLEAEDAASRQAAKAA
CDWLVAREVTNVKGDWAIRRPELRPSGWAFQYRNDYYPDLDDTAVVVMALQRLDPEGYRE
VIERASRWIVGMQSSNGGWGAFDVDNTYYYLNHIPFADHGALLDPPTADVSARCLGMMLQ
LGYDTDHPAVRKAVDFLLDEQEPDGSWYGRWGVNYVYGTWSVLNALNAAGFQPDHPAMHR
AAAFLLASQRADGGWGEDCATYWDACRGESLEGTPSQTAWALMGLMAAGQVESEAVQRGV
DYLVAQPLDGANWRERLWTGVGFPRVFYLKYHGYSSYFPLWALARYRNLMRSNDRRVRHA
I
>A0A8E0L4P5|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia thailandensis MSMB43|TrEMBL
MNDMTEMHTLDATAVPAAPAAADAPAPSAATTGLDAAVARATDALLAAQNADGHWVYELE
ADSTIPAEYVLLVHYLGEEPNAELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYF
ALKVIGDDENAEHMQRARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIILLP
QWFPFHLSKVSYWARTVIVPLLVLNAKRPVAKNPRGVRIDELFKSAPVNTGLLPKQPHQH
AGWFAFFRAVDGVLRLADGLFPRYTRERAIRQAAAFVDERLNGEDGLGAIYPAMANAVMM
YAALGYPEDHPNRAIARQSIEKLLVVGEEEAYCQPCLSPVWDTSLAAHALLETGDERARE
AAVRGLDWLVPRQILDVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVVMAMDRVAK
HDQTDAYRESIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVS
GRCLSMLAQLGETSASSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAG
LGHDDPRVKRAAQWLLSIQNPDGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAG
EVDNPAVARGIGHLLGTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNL
KRAGAARVTVGM
>A0A844T293|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium cajani|TrEMBL
MDSVNATSREALESQVLESKVLESSIASATQGILGFQQSDGHWVFELEADCTIPAEYILL
RHYLAEPVDAVLEAKIGNYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDSTDSP
HMVRAREAIHARGGAINSNVFTRFLLATFGVVTWRAVPVLPIEIMLLPFWSPFHLNKISY
WARTTMVPLMVIAALKPRAKNPRGVGIDELFLQDPRSIGMTAKAPHQSMAWFLLFRSLDA
ILRVIEPMFPKSLRKRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKDENYPP
RATTRRGIDKLLVIKDDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAARQGLDWLIPK
QELEVKGDWAAKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGVTGYDAAIA
RGQEWIEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGE
TEKTSKHVAGGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDHKDPMIRKAA
DWLASIQNEDGGWGEDAVSYRLDYKGWEAAPSTASQTAWALLALMAAGEVDNPAVARGVE
YLIATQNKKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A5J6F4J5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces nitrosporeus|TrEMBL
MTATTDPGTGATDLRGVPGATAEQTTITADDVLAAARQAAGRSVEHLLGRQDGEGWWKGD
LATNVTMDAEDLLLRQFLGIQDPATVQAAARFIRGEQMGDGTWNTFYEGPPDLSATIEAY
VALRLAGDRPDDPHMRRAAGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMFL
PSWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDATRPNPPRPMAPAASW
DGLFQRLDKALHAYHRIAPGRLRRAAMNEAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLGHPVMRAGLASLDRFAVWREDGSRMIEACQSPVWDTCLATIALADAGVAPDHPAL
VRAADWMLGEEIVRPGDWAVRRPRLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDQ
ARVDAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGRAGDPATRRGIDWLLAEQEESGAWFGRWGVNYIYGTGSVVPALVAAGLPAGHP
AVRRAVTWLESVQNDDGGWGEDLRSYVEEKWIGHGASTASQTAWALLALLAAGERGSRSV
RRGVTWLTETQQPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRFVHGEPSALRT
AAAAGKEA
>A0A552DUB1|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa Ma_QC_B_20070730_S2|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
KRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKALDNFAIE
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPSIIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKSVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYSDLKAMIDPNTADVTARVLEMLGTCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYQALI
>A0A060URZ1|squalene-hopene cyclase|EC 5.4.99.17|Acidithiobacillus ferrivorans|TrEMBL
MNRILQPMHYGARIFRAPLDRVIAEARTALSSLQAEDGHWCFEFEADCTISAEYILMQHY
MDERDGPLEAKIAIYLRNKQADHGGWPLYYGGPFDLSASVKAYYALKLAGDNPDLPHMRR
AREAILAHGGAEHANVFTRITLALFAQVPWRAVPFIPVEIMLLPRWFPFNIYKVASWSRT
VMVPLFILCSLKARAKNPLQVHIHELFRRPPEQIADYFSHARQGIVAHLFLSLDRFWRLM
EDWIPQRIRCRAVQKAEMWFIARLNGEDGLNGIFPAMVNAHEALELLGYASDHVYRQQTR
AALRKLVVERASDAYCQPCVSPVWDTCLALHALLEQDGEVSPAVQSGIQWLKDRQIGAEP
GDWQEQRPNLAGGGWAFQYANPYYPDLDDTAAVGWALARAGRAEDRDSIERAANWLAGMQ
SSNGGFAAYDVDNTHYYLNEIPFADHKALLDPPTADVTGRVVAFLAHLARPRDRDILRRA
VAYLLREQESSGAWFGRWGTNYIYGTWSVLMALAELDDPSLQPAMERAAYWLRAVQQSDG
GWGENNDSYGDSGLAGMGQASTAAQTAWACLGLMAAGDQDSLALHRGMAWLQMHQEEDGR
WPDLFFNAPGFPKVFYLIYHGYSLYFPLWALARYRNLGCIAGD
>A0A3B0AUW1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces klenkii|TrEMBL
MTATTDGSTGALPPRAAAATDSTTARRTTAQSTTARPPLPEGEAPGALAAAERATARAAE
HLLSRQDEQGWWKGDLETNVTMDAEDLLLRQFLGVQDEETTRAAALYIRSEQRPDGTWAT
FLGGPGELSTTIEAYVALRLAGDAPDAPHMAAASAWIREQGGIAAARVFTRIWLALFGWW
RWEDLPELPPEIMFLPKWFPLNLYDFGQWARQTIVPLTVVSAKRPVRPAPFPLDELHTDP
ARPNPPRPLAPAASWDGAFQRLDKALHHYRRFPLRRLRRLALDSAARWIIERQENDGCWG
GIQPPAVYSIIALHLLGYDLDHPVLREGLKSLDRFAVWREDGSRMIEACQSPVWDTCLAT
IALADAGVAPDHPALVKAADWMLAEQIDRTGDWAVRRPGLTPGGWAFEFHNDTYPDIDDT
AEVVLALKRVRHPDPARVETAVRRAARWNLGMQSKNGAWGAFDADNTSTLPNRLPFCDFG
EVVDPPSADVTAHVVEMLAFLGERHDPRTQRGVEWLLGEQEESGAWFGRWGVNYVYGTGS
AVPALVAAGIPASHPAVRRAVRWLEGVQNDDGGWGEDLRSYRDPEWIARGESTASQTAWA
LMALLAAGEREGKAVERGVTWLVDTQRADGSWDEPHFTGTGFPWDFSINYHLYRQVFPLT
ALGRYVHGELFTPDRLEA
>A0A4S2RP91|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. A1277|TrEMBL
MTATTDGSTGAVDPRVASASRPTTESTIAADAVLAAARRAAERSVEHLLGRQDEQGWWKG
DLATNVTMDAEDLLLRQFLGIQDPATVRAAGRYIRGEQLGDGTWATFHGGPGDLSATIEA
YVALRLAGDRPEDPHMTRAAGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMF
FPKWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPDHPNPPKRPAPAAS
WDGLFQRLDKALHVYHRFAPRRLRRVAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVAPDHPA
LVKAADWMLGEEIDRPGDWAVRRPRLQPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPE
PARVDAAIARGVRWNVGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHV
VEMLAMEGHAGHPVTRRGIEWLLAEQDAGGGWFGRWGVNYVYGTGSVVPALIAAGLPATH
PAIRRAVDWLESVQNDDGGWGEDLRSYIEEKWIGQGASTASQTAWALLALLAAGRRDTVA
VTRGIAWLTETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFADR
TATREEV
>B1TFK6|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia ambifaria MEX-5|TrEMBL
MIRRMNKPAPSPWSALDAAIARGRDALMRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDARQEKMARYLRAIQRLDTHGGWDLYVDGDPDVSCSVKAYFALKAAGDSEHAPHMVRA
RDAILALGGAARSNVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWTRTT
MVPLLVLCSLKAHARNPRNIAIPELFVTPPDQERHYFPPARGMRRAFLALDRVVRHAEPL
LPKRLRQRAIRHAQAWCAERMNGEDGLGGIFPPIVYSYQMMDVLGYPADHPLRRDCENAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVAVHEAGAPASALDELDARIARAY
DWLAERQVNDLRGDWIENAPADTQPGGWAFQYANPYYPDIDDSAVVTAMLDRRGRTHRNA
DGTHPYAARVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRADDRASLARAIDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALAGED
PSQPYIARALAWLRARQHADGGWGETNDSYIDPALAGTNAGESTSNCTAWALLAQMAFGD
GESESVKRGIAYLQSVQQDDGFWWHRSHNAPGFTRIFYLKYHGYTAYFPLWALARYRRLA
GGASSAGAHAVPASTAADAALA
>A0A6N6W2R0|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia madseniana|TrEMBL
MNDLSQAQPLDAVLPEFADAALNVSNAVPSAVSSAAPDAAPQAFATSLDAAITRATDAIL
GAQKPDGHWVYELEADATIPAEYVLLVHYLAETPNLELEQKIARYLRRIQLADGGWPLFT
DGAMDVSASVKAYFALKMIGDSPDAEHMVRAREAILANGGAETVNVFTRILLALFGVVSW
RAVPMMPVEIMLLPMWFPFHLSKVSYWARTVIVPLLVLNAKRPVARNPRRVRIDELFRGA
PVNTGMRDRAPHQHLGWFRFFRGVDVMLRMIDGLFPKVTRERSVREAVRFVDERLNGEDG
LGAIFPAMANSVMMYDVLGYPADHPNRAIARQSIEKLLVIKDDEAYCQPCLSPVWDTSLV
AHALLETGEAHAEQAAERGLAWLRPLQILDVRGDWISRRSNVRPGGWAFQYNNAHYPDVD
DTAVVAMAMQRSAALTQSDVDREAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFS
DHGALLDPPTADVSGRCLSMLAQLGEFPQGSEPAQRAFDYMLKEQESDGSWYGRWGLNYI
YGTWTALCSLNAAGLPHDDPRMKRGAQWLLSIQNEDGGWGEGGESYKLDYHGYERAPSTA
SQTAWALMGLMAAGEVNHEAVARGVEYLQREQREHGLWDETRFTATGFPRVFYLRYHGYR
KFFPLWALARFRHLKRNGLTRVAVGM
>A0A4U3LMK2|squalene-hopene cyclase|EC 5.4.99.17|Kribbella jiaozuonensis|TrEMBL
MTDAERADVRVEECLDAAVSYLRSLQHDDGWWKGDLATNVTMDAEDLMLRHFLGVATAQT
DAETARWIRSQQREDGTWATFPGGPGELSTTVESWVALRMAGDDPGAPHMARAASFIRSN
GGVEKARVFTHIWLALFGLWSWDDCPDLPPELIFLPSRVPLNIYNWACWARQTIVPLTIV
SAHRPVRPVAFTVEGLRAGRADAAQAAPWTLEGAFQRLDVVLNAYSRWGPRGPSKGLRRL
AMRRAVEWIVARQEADGGWGGIQPPWVYSLIALDLMGYAIDHPVMAAGLRGLEGFTVHTE
TAEGPARWLEACQSPVWDTGLAVGAMLDAGVEPDDKTVLKATDWLLAEQIDAPGDWQVRR
PGLVSGGWAFEFANDGYPDTDDTAEIVLALRRVEHPEPGRLRKALDDAVEWTTGMQSADG
GWGAFDADNTDTTPLKLPFCDFGAVIDPPSADVTAHVVEMLAAEGRTDSAECQRGVRWLL
DSQEKDGSWFGRWGTNHVYGTGAVVPALIAVGMSGNDPVIRRAVRWVEEHQNADGGWGED
LRSYVDPLWIGRGDSTPSQTAWGLLTLLAAGERGDAVRRGVGYLVDTQRADGGWDEHRYT
GTGFPGDFYIGYHLYRLVFPIWALGRYLGRNR
>A0A8I1UZ75|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MNQLNPADYLDVEGAIKAATDAVLAQQKPDGHWVYELEADATIPAEYVLLVHWLGETPNL
ELERKIGVYLRRIQGAHGGWPLYHEGAFDISATVKAYFALKMIGDDIEAPHMARAREEIR
KRGGAIKANVFTRILLCLYGQASWHDVPTVPPELILLPRWFPIHLSKMSYWARTVIVPLL
VLCALRPLAKNPRGIHVPELFVPGVPAASPRAPHQSAGWSAFFGALDRVLKIVPWPRGAR
ARAIEKCRAWTTERLNGEDGLGAIYPAMANSVMMYDVLGYPADHPDRAIARKSVENLLVV
KDDEAYCQPCVSPVWDTALVAHALLETKDEKACAAVTHGLEWLRPLQVLDVKGDWAEEKP
DVRPGGWAFQYRNDYYPDLDDTAVVVMAFDRAGVPQTDVAIARGREWVEGLQSKDGGWGA
FDADNSYYYLNNIPFADHGALLDPPTEDVSGRCVGMLAQLGNGGQALADGIAYLRKTQRE
DGSWWGRWGVNYIYGTWSALAGLNGAGLKPDDPTMKRGADWLVAIQNPDGGWGENCDSYK
LDYKGYEPAPSTASQTAWALLGLMAAGQVDHPAVARGVNYLKATQEADGLWSQAHYTGGG
FPRVFYLNYHGYPKFFPLWALARYRNLKTGNSRRVEFGL
>A0A7W7N0B0|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura catellatispora|TrEMBL
MTTIEAPGLTGAAAAAVEAARDHLLGLQSPEGWWKAELETNVTMDAEDLLLRQFLGIRAD
GETREAARWIRSRQRDDGTWANFFGGPPDLSTTIEAYVALRLAGDPAGAAHMRRAAGCVR
EAGGIEASRVFTRIWLALFGQWSWDDLPVMPPELMFLPSRVPLNVYDWACWARQTIVPLT
VLGSLRPVRTLPFDLAELRSGVRPAQDAKGWGRVFTTLDRALHVYEKRPVRPLRTAALRR
AAEWIIARQEADGCWGGIQPPWVYSLMALHELGYGLDHPVVRRGLAGLDRFTIRDEKGRR
LEACQSPVWDTVLAMNALSDAGTPPGDPALLRAARWVAAEEVRGPGDWQVRRPSLPPGGW
AFEFDNDVYPDTDDTAEAILALRRSGLPGAAEPIGRAVRWLAGMASRDGGFGAFDADNTR
ELCTRLPFCDFGAVIDPPSADVTAHVVEALAKEGHARTTVVKRAVVWLLKAQEADGSWFG
RWGANHVYGTGSVVPALIAAGVRPDKPAIRRAVGWLEEHQNDDGGWGEDLRSYDDPAWIG
RGASTPSQTAWALLALLAAGERSAAVDGGVRWLVDHQRPDGNWDEEHFTGTGFPGDFYIN
YHLYRLVFPISALGRYVAASNEVRES
>A0A7C8ATF1|squalene-hopene cyclase|EC 5.4.99.17|Desulfuromonadales bacterium|TrEMBL
MELRKYQISSALTSFTTESAAPVIEPPRKVPGKVHHLPPSIWKKMAGESKSPLDRAIERT
RDFFFREQLPDGYWWAELESNVTITAEYIMLFHFLGMVDRHREQKIANYIISKQTEEGAW
TLWYGGPGDLSTTIEAYFALKMAGFSAEHHVMKRARDFILANGGILKARVFTKIFLALFG
EFSWLGVPSMPIELMLLPNWAYFNLYEFSSWSRATIIPLSVVMAERPVRKLPPRARVQEL
YVRPPRPTDYTFTHEDGILTWKNFFIGVDHILKVYESSPIRPFKKKSVSMAEQWILDHQE
PSGDWGGIQPAMLNSILALHCLGYANDHPAVAKGLEALANFCIEDEESLVLQSCVSPVWD
TALVLVAMQEAGVPADHPALVKSAQWLLDLEVRRKGDWQIKLPDLEPGGWAFEFLNDWYP
DVDDSGFVMLAIKDIKVRDKKHKEQAIKRGIGWCLAMQSSNGGWGAFDKDNTKYLLNKIP
FADLEALIDPPTADLTGRMLELMGNFDYPLSHPAAVQALEFLKQEQEPEGPWWGRWGVNY
IYGTWSVLCGLEAIGEEMSQPYVKKAVNWIKSKQNLDGGWGEACESYCDRSLMGCGPSTP
SQTSWALLSLFAAGDVCSKAASRGVEYLMSTQKQDGTWDEDAFTGTGFPKYFMIKYHIY
>A0A7H8NYX4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. NA03103|TrEMBL
MTATTDGSTGAALRPLAASASDTDSTIPAAAAGVPEAAARATRRATDFLLSKQDAQGWWK
GDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDSPDAPHMARASEWIRSRGGIAASRVFTRIWLALFGWWKWDDLPELPPELI
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFSLDELHTDPARPNPPRPLAPAA
SWDGAFQRIDKALHAYRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPEDHP
QLVKASDWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHH
DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAVEGLAHDPRTRRGIQWLLDAQEADGSWFGRWGVNYVYGTGSVIPALTAAGLPTS
HPAIRRAVRWLESVQNEDGGWGEDLRSYRYVREWSGRGASTASQTGWALMALLAAGERES
KAVERGVAWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFA
KKSPAAEAPTASVVAEVKGS
>W9D4F8|squalene-hopene cyclase|EC 5.4.99.17|Frankia sp. CcI6|TrEMBL
MSLTSDPSPAAPKAAKSSKRVNIPAPATPDAYGISRSSPPLSGGGVSGGGVSGGGAATAD
GTPPTTQTSVDPDLAAAMTAANQARDHLLGLQSEEGWWKGDLETNVTIDAEHLFMKQFLG
IRTEEETEPIARWVRSQQLADGGWATYYGGPAELSTTVEAYIALRLAGDEPDAPHMAAAA
ALIRSQGGVAAARVFTRIWLATFGEWSWDDVPVLPPELIFLPSWFPLNVYDFGCWARQTI
VALTIVGSLRPVRDLGFSIDEIKVAAPVTPPKPAPLHSWEGAFERLDAILHRYERRPIKV
LRTLALRRATEWVVARQEADGCWGGIQPPWIYSVMALHLMGYPLNHPVIATAFRGMERYI
IRRETPEGPTAQIEACQSPVWDTALAVVALSDAGVPADHPAMVRAGRWLVDEEVRVAGDW
AVRRPALAPGGWAFEFDNDFYPDTDDTAEVVLALRRLLGGSHVTPGGTVTPSGSVTPGGT
AELSPAARDRASRGLAAVDPQLAGAMRAAAARGVDWSVGMRSSDGAWGAFDADNVRTLTA
KIPFCDFGEVVDPPSADVTAHIVEMLADLGRSDHPITRRAVQWLLDNQEPGGSWFGRWGI
NHVYGTGAVVPALIAAGVPADHPAITAAVRWLLEHQSPDGGWGEDPRSYDDPAWIGRGEL
TASQTAWALLALLAVDPHSKAVKRGVRWLCETQRPDGTWDEPQFTGTGFPGDFYLNYHLY
RLVFPLTALGRYVTLTGVATP
>A0A7Y9BJX0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. BR123|TrEMBL
MAKGVGATTGAGAVAAVAPPGVREAVERATRHLLRQQDPAGWWKGDLETNVTMDAEDLLL
RQFLGVRDEATTRAAARHIRREQRADGTWATFHGGPPELSATVEAYVALRLAGDAPDAPH
MTRASAWIRAHGGIARARVFTRIWLALFGWWSWDHLPELPPELVFLPPWVPLNIYDFGCW
ARQTIVPLTVVSAHRPVRPAPFALDELHTDARRPVPAARLAPLGTWNGLFQRMDKVLHVY
RRFAPRPLRAAAVATAARWIIERQENDGCWGGIQPPAVYSLIALHLLGYDLGHPVMRAGL
ESLDRFAVWREDTAPGPDGRPGDTGPVRMVEACQSPVWDTCLAAIALADAGLPPDHPALV
KAADWMLDEEITRRGDWAVRRPGLAPGGWAFEFHNDTYPDIDDTAEVVLALRRVRHSDPA
RAEAAIARAVSWTLGMQSRNGAWGAFDADNTSTLPNRLPFCDFGEVVDPPSADVTAHVVE
MLAAEGRAADPRTRRGIAWLLAEQEPNGSWFGRWGTNYVYGTGSVVPALVAAGIAPAHPA
VRRAVAWLESVQNDDGGWGEDQRSYRDPAAWAGRGDSTASQTAWALMALLAAGERDGKAV
ERGISYLTGTQLADGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGEPFAPGT
P
>A0A5Q0L911|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces fagopyri|TrEMBL
MTATTDGSTGALPPRAAAASEIPTETTPVAAGTVETRDVAKYAIQRATDHLLSRQDAEGW
WKGDLDTNVTMDAEDLLLRQFLGILDETTARAAGLFIRGEQREDGAWATFYDGPGDLSAT
VEAYVALRLAGDAPDAPHMTKAAAWVRERGGIASARVFTRIWLALFGWWKWDDLPELPPE
LIYFPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPDNPSPVRPTAP
VASWSGVFQRLDKALHQYRRVAPQPLRRAAMNAAARWIIERQENDGCWGGIQPPAVYSVI
ALHLLGYDLDHPVMRAGLESLNRFTVWREDGARMIEACQSPVWDTCLAAIALADAGLPAD
HPQLVKAADWMLGEEIVRPGDWAVKRPHLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVR
HPDPERVEKAIGRGVRWNLGMQSKDGGWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVT
AHVVEMLAVEGLAHDPRTRRGIAWLLAEQEPNGSWFGRWGVNYIYGTGSVVPALTAAGLP
GSHPAIRRAVGWLETVQNEDGGWGEDLRSYDDAAEWSGRGASTASQTGWALLALLAAGER
ESKAVERGVAWLAETQLPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEP
FAEVEGG
>A0A7V4W9U1|squalene-hopene cyclase|EC 5.4.99.17|Armatimonadetes bacterium|TrEMBL
MHTTDIVSDTAKRLQVRSAEHNRIEEALDRSIRFLLDAQHDDGYWVGELEGDTILESEYI
ILLRFLGRKREHKLKKAAAYILSKQMDNGGWAIFPGGPVDVSASVKAYLALKLTGSKPDE
HYMVRAREAIRQVGGVPAVNSYTKFYLALLGQIPWEFVPAVPPELVLLPNWFYFNIYEIS
SWSRTFVVPLGIIWAYKPVVNLDRTEGIPELLDEGELERVRSYIDRPFLTWRNFFLAVDS
GIKLAEKLRLLPFRKRAVQRSAQWMLSHCEHSAGLGAIFPPIVYSLIAFRALGYDDSHPQ
VVRAMSELEALEIEEEDTLRLQPCVSPVWDTAIAINALIEAGLPPDHPALISATRWILSK
EVKQRGDWSVKRPKLEPGGWYFEFANEFYPDIDDTAMVLIALAKVADVPGKSDACRRALT
WLAGMQGRDGGWASFDVDNNKSIFNNIPFADHNAMLDPSTSDITARVLEMLSYYTFTRES
VLCRRAIDFLSKQQEPDGSWYGRWGVNYIYGTWQAIRGLRAIGVEPTNPMIRRGAQWLLS
VQNEDGGWGESCISYYDPSLKGKGESTASQTAWAIMGLISAGEGKSAAVKAGIDYLVRNQ
TEEGTWLEEAFTGTGFPKVFFLRYHLYRHSFPMMALGMYRREVGQ
>A0A6I5HDH1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID486|TrEMBL
MTATTDGSTGATLPPRAAAASDTTLTTPETAGVPEAAARAARRATDFLLAAQDNQGWWKG
DLETNVTMDAEDLLLRQFLGILDEHTAQAAAKFIRGEQREDGTWATFYGGPGDLSATVEA
YVALRLAGDVPDAPHMARASAWIRERGGIAAARVFTRIWLALFGWWKWEDLPELPPELLY
FPTWFPLNIYNFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAQPNPPQPLAPVAS
WDGLFQRLDKVVRGYRKVAVRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVLREGLASLDRFAVWREDGARMIEACQSPVWDTCLAAIALVDAGLPVDHPQ
LVKAADWMLGEEIVRPGDWAVRRPHLPPGGWAFEFHNDNYPDIDDTAEVALALRRIRHHD
PERVDRSIGRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAAEGLAHDPRTRRGIDWLLAEQEADGSWFGRWGVNYLYGTGSVVPALTAAGLPGSH
PAIRRAVAWLERVQNDDGGWGEDLRSYKYAKEWSGRGASTASQTAWALMALLAAGEKGSR
AVERGVQWLAETQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFER
KLLAPAGPAPTRPEGD
>A0A3S9V680|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus lutimineralis|TrEMBL
MRSAVDDEIERLTTALIEQQRQDGSWHFCFENGTAIDAYVIILFRVLDVPNEALIRQLHD
RILAAQQPDGCWRLFTDEEEGNLSASVEAYYALLYSGYSQTTDEPIQRARRYILSKGGLG
KITNILTKAILSITGQRKWPASISSIPLEILLFPKYFPINIYDFSGYSRIHLIPMLIMGD
KQFSITNAHTPNLSDLQVRPVDEVEEPLPRGYQEMQDSIKTGLGWLIGTRRHIHETAITR
AEKFMLKRIEADGTLYSYASSTILMIFALLALGYEQQHPLITDAIQGLTDMQFRYDGTTT
IQNSPSTVWDTALLAYALQEAGIPADHPAIRRAAAYLLPRQQHKTADWSIHNPGTQPGGW
GFSETNTINPDVDDSTAALRAILSFSNTDPSYLKSWNRGLNWVLSMQNKDGGWPAFEKDT
NNEMLTWLAIDGAKSAAIDPSEADLTGRTLEYLGNFTGLDIRYPFIKQGAEWLIGHQEKD
GSWYGRWGVCYIYGTWAALTGLAAVDLSANHETLQNGVRWLLDIQNPDGGWGESCRSDRL
RRYVPLGESTPSQTAWALDALIAVQAQPTSETDQGIQRLIALLHEDDWKSTYPTGAGLPG
HFYSHYHSYRYIWPLLTLSHYKQKYGKN
>A0A7K2S6U6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8364|TrEMBL
MTATTDGSTGAANPSEATAHDPTDTTTAADDLTVAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLSIQDPETTRAAALFIRGEQLGDGTWNTFYGGPGDLSATIEAY
VALRLAGDRPDEPHMARAAGWIRDQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPDHPNPPRKLAPPTSW
DGLFQRLDKGLHLYHKFAPRPLRRVAMNLAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMKAGLASLDRFAVRREDGARMIEACQSPVWDTCLATIALADAGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARLQAAIDRGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLASHPRTREGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALITAGLPAGHP
AIRRAVAWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDTRPV
ARGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFADRA
MAAEGA
>A0A7H8T120|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces chartreusis|TrEMBL
MTATTDGSTGARPPRAAAASETDSENPAAAGVYEAAEGAVRRATDFLLAKQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDEETTRAAALFIRGEQREDGTWGTFYGAPGELSTTIEAY
VALRLAGDAPDAPHMARASAWIREQGGIAGARVFTRIWLALFGWWKWEDLPELPPELIYF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPADPNPLKPLAPAASW
DGAFQRLDKALHQLRKVAPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLQHPVMREGLASLDRFAVRREDGARMIEACQSPVWDTCLATIALADAGVPADHPQL
VRAADWMLGEEIVRPGDWAVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHDP
ERLEKAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIRWLLAEQEPDGSWFGRWGVNYIYGTGSVVPALVAAGMPGSHP
AIRRAVTWLESVQNDDGGWGEDLRSYRYVKEWSGKGASTASQTGWALMALLAAGERDSKA
VERGVEWLAATQLADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFTET
VVRVVVEDTAAVEAKGS
>A0A6H1RIM7|squalene-hopene cyclase|EC 5.4.99.17|Saccharopolyspora sp. ASAGF58|TrEMBL
MRTGVVSASAARADARIALAAGRDYLLSLQHPDGWWKGELETNVTMDVEDLLLRQFLGIR
TAAETEQAARWIRAQQRPDGTWANFYGGPGDLSTTVEAYTALKLAGDDVDAEHMAVARDW
ILARGGLEATRVFTRIWLALFGEWSWDELPAMPPELVLLPKWFPLNVADWGCWARQTVVP
LTVVCTLRPCRNLGIDVRELRTGRAAEGVRPQWSWKYGFHALGQVLHRYHRRPLKALRKH
AMLRAAEWIVARQEADGSWGGIQPPWVYSLLALHLLGYPLDHPVLRHGLAGLEGFLIREQ
TPAGPVRRLEACQSPVWDTVLGMQALRDAGVPADHPSLRRATDFLLTEEIRVKGDWSVRR
PDLPPGGGWAFEFDNDGYPDIDDTAEALLALNRIEHPDREAVRGAIERGVRWLRGMQSRD
GGWGAFDADNTRTLVRKLPFCDFGEVIDPPSADVTAHVVEALAALGHDDRVLRRGVKWLL
DNQEKDGSWFGRWGANHVYGTGAVVPALVRAGLEPDHRALRRAVRWLERHQNADGGWGED
LRSYRDPEWIGRGDSTASQTGWALLALLAVGRHGTDAVHRGVQYLARTQRVDGGWDEPQF
TGTGFPGDFYINYHLYRVIFPLTALGRYQRAGD
>A0A6N1YAP2|squalene-hopene cyclase|EC 5.4.99.17|methanotrophic endosymbiont of Bathymodiolus puteoserpentis|TrEMBL
MSQKNSSWNNWQLLTEKGRQIWAYKPASQDINAHLHNANNFSEQELQAFAKDFSFDRQIN
PSASDKVFRQQYQKNNAPAYSGTRPKAESAEEQKLIDSLINGMHYFSRLQSDEGHWPGDY
GGPLFLLPGLLIAAYLTDTPFPKPHQEMMKVYLFNHQHTNGGWGMHIEGQPTMFGTVMQY
VSLRLLGTPQEDSRLQKAQTWIKENGGATGIPSWGKFYLSILNLYSWDGFNSLFPEMWLF
PKWLPVHPSRYWCHSRMVYLPMAYCYAQRIQVPENDLILSLRKEIYNEDFASIDWPKQRN
QVCAKDCYTTQSPVLKWMNAFTNGYEKIRPQWLRNKANNYLLKYINAEDAQTEYLDIGPV
NKAINSMCIWHAYGKESEPFKKHVARWYDYLWVAEDGMKMSGYNGSQLWDVAFATRAMLE
SDIGKLFPKTLEKSYHFINDMQILAEHETHEEFFRHPMIGSWPFSTAEQGWPVADCTSEG
LSATLAIHKTGLFKQNISDQRIKQAVDIILSYQNKNGGWPTYELSRAPSWLEKLNPSEVF
ADIMIDYSWTECSAACVVALLEILELYPDYKRNEIEQAITDGLKFIVKQQKLDGSWYGGW
AVCFTYATWFGIEALVQGKDYIDAQLRTNCINKACDFLLNKQMTDGGWGETYESCAKMVY
SQAETSQVVNTAWALLALQAAKSPEKTALQRGINLLLDRQLENGDWAQENISGVFNYNCM
ITYSAYRNIFPIWALNRFYQHKHY
>A0A849IZ27|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Dormibacteraeota bacterium|TrEMBL
MRSQTEPSDEAVDATRAAVDRAVANLLARQLPDGSWMGELESNAAITAEYLLMRRYLEVT
DTAREAAAIRYLRSQQQADGSYSIAPGVDGDVSVTAEVWVAMRAAGVPADDPAVAAARRF
VADHGGIHATRVFTRIWLALGGLWPWSELPVVPPEWVLVPGHRIGSIYDLASWARATTVP
LAILRTLETVFPLAGPSRSELPLGAPVPPVGSLTWRSVDRLVRLYGKLPKIGLRRLALAE
AERWVVRHQERDGSWAGIQPPWVYGLMALRARGHGLDYPVLRRGLEALDTFGIEDEQGFR
LQACVSPVWDTALALWALLDAGLDRDHPAVRRAVDWLVDREVQGLGDWAVHVPGVAAGGW
PFEFYNDQYPDTDDTAIVLCALDAAGHRRDDGTPAGAAMTRAVNWLQAMQGSDGGYAAFD
RDNNRHWVERLPISDFGEVLDPPSPDVTAHVVEAFTRCGGAELARRRALAWLRASEEGAG
AYFGRWGVNYVYGGAATATALAAAGERADRERLLRLGRWVRRHLHDDGGFGESVLSYHDP
RHIGQGEATPSQTGWALLSLLAAIEGSQGLDGGDELEGAALAAADWLVRQQREDGSWSDR
LFTGTGFPRAFYLRYEMYATVFPLMALARVVGPDKGLKGPS
>A0A0E0TCC4|squalene-hopene cyclase|EC 5.4.99.17|Geobacillus sp. (strain Y412MC52)|TrEMBL
MVADERSALIDALKRSQSVDGSWRFPFETGISTDAYMIILLRTLGIHDEPLIQALVERIE
SRQDANGAWKLFADEGDGNVTATVEAYYALLYSGYRKKTDSHMQKAKARILEVGGLERVH
LFTKVMLALTGQHSWPRRFPLPLVFFLLPPSFPLNMYDLSVYGRANMVPLLVVAERRYSR
KTDNSPDLSDLAASRNDWRLPDTEALWSYVKRSLTGLPAWLHRAAEQRAVRYMLEHIEPD
GTLYSYFSSTFLLIFALLALGYPKDDPHIARAVRGLRSLRTEIDGHTHMQYTTASVWNTA
LASYALQEAGVPPTDRTIEKANRYLLSRQHIRYGDWAVHNPYGVPGGWGFSDVNTMNPDV
DDTTAALRAIRRAAAKETAFRHAWDRANRWLFSMQNDDGGFAAFEKNVGKRFWRYLPIEG
AEFLLMDPSTADLTGRTLEYFGTFAGLTKDHSAIARAIDWLLDHQEADGSWYGRWGICYV
YGTWAAVTGLSAVGVPIDHPAMQKAVRWLLSIQNDDGGWGESCKSDGAKTYVPLGASTPV
HTAWALDALIAAAERPTPEMKAGVRALVRMLHHPDWTASYPVGQGMAGAFYIHYHGYRYI
FPLLALAHYEQKFGPFVD
>A0A892IDA0|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia dolosa|TrEMBL
MNDLTDMATLSAGAAPAADLDAAVARATDALLAAQNADGHWVYELEADSTIPAEYVLLVH
YLGETPNLELERKIGRYLRRIQQADGGWPLFTDGAPNVSASVKAYFALKVIGDDENAEHM
QRARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWA
RTVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHVL
RAVDGLFPKYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRA
IARKSIEKLLVVHDDEAYCQPCLSPVWDTSLAAHALLETGDPRAEDAALRGLEWLRPLQI
LDVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVAMAMDRAQKLRQSDTYRESIARA
REWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGESA
LTSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCALNAAGLGPDDPRVKRAAQW
LLSIQNKDGGWGEDGDSYKLNYRGYEQAPSTASQTAWALLGLMAAGEVNNPAVARGIDYL
LAEQKEHGLWDEVRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A3M1HAB1|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MALDELYPVPKEELEYTVGKAEKFFSLRNFFLIVDKILKCLENNVLKLFQKRALKVAEKW
TLDHQLDTGDCAGIFPAMANTVLALYLLGYPLDSEPIQKGLAAIDRFQIMEGNTLRQQSC
VSPVWDTAWVIYGLSTCGYTYQHPQVAKAMEWLFANQINIKGDWALKNPNTPPGGWAFQF
HNDLNPDTDDTAVVLMALLSDNLKREDKRNEIRRAFYWLLTMQNLDGGWGAFERDNDYRI
FNEIPFSESDNLIDPSTEDVTGRVLEAAGQMGMDKNHPQIAAAIEYLKRVQDPRGSWYGR
WGVNHIYGTWSVLCGLASVGEDMRAPYVRKAVEWLKSIQNKDGGFGESCRSYVDESWIGK
GNSCASQTAWALMALIAAGEADSESAKKAVEYLLSTQKEDGTWDEPEFTGTGFPQFFLIR
YHMYRIYFPLLALARYVQALKEKE
>A0A3M1H1S4|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
TADGRIWVQPCLSPIWDTGWSVLALCRAGLDRDDPRIRKATDWLYAKQIRRPGDWSRKCP
GVPAGGWAFQYHNDFYPDTDDTSVVLMALLNSHYRDDPARREAFDRGLGWLLGLQNADGG
WGAFERDVDNPIYNEVPISDSTCMLDPSEVDVSGRCVEVLAKIGYPRTHPAMARAIAYLL
REQEHDGSWWGRWGVNYIYGTWSALCGLGAARLSPQAPAIRRAVAWLESVQQPCGGWGES
CRSYEGGPKGQGPVTPSQTAWAVMGLLAAGHAASESCRRGVAWLLEHQRPDGGWDETEFT
GTGFPGIFYLRYEGYALYFPLLALARYRAAMPR
>A0A4V6MSE1|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus thalictri|TrEMBL
MLLNILGRKVPSGKRWLAVVTAEQANAEINRLASSVSSRQEADGAWRFCLDAGPLTNSFF
IIALRALEMEEERLIGQLADAIRARQEPGGAWKLYHDEPEGNISATVQSYCALLLSGKHK
ADEPHMAAAKRFIDAQGGTARTDLITKVILAMIGQYRWRNHFMVPIELLLLPPEAPVSFY
DFAGYARVHIAPVLLAADRRFISGLPVFQTLPFAGGTAPLEGEQTAGGSPPPELEPQLTE
AQRSIKELAAKLIGLPEKLHERARAAGVRFILERLEPNGTLYGYTTSTLLMVFALLAVGY
DKRDPVIVRAVAGLKTLMCKLDGHSYLQNFTSTVWDTALLTHALQQARMAEEAVIGKAGR
YLLSRQQTAYGDWRIHNPRVAPGGWGFSDVNTINPDVDDTTAVLRAIRRLRKADAKYSHA
WGRGLNWVLSMQNADGGWPAFEKNTDNKLLTLLPIENVRAAGIDPSTADLTGRTLEFLGS
DAGLTAKLPAVERAVRWLMNHQDEDGSWIGRWGICRIYGTWAALTGLMAVGCPPGHTAVR
RAVRWLENVQNTDGGWGESCASDVAGIYVPLGYSTPSQTAWATEALLAAERRPTAAAQRG
VRFLLEAGHWQTGDWRLRYPTGAGLPGSMYMAYHSYNIIWPLLALSRYREAAK
>A0A0E1VXK8|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia pseudomallei 1710a|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A524MLU3|squalene-hopene cyclase|EC 5.4.99.17|Nitrosomonadales bacterium|TrEMBL
MKEIDTLADLTHENTDSSSTTPLDYQRPSNHDIATLADALASARTALLSLQKEDGHWCFP
LEADCTIPAEYVLMMHFMDDINIELETKLARFIRTKQDLKHGGWPLYFGGHFDLSCTVKA
YYALKLVGDSPDAPHMVAARTAILEYGGAARANVFTRILLAMYGQLPWRGVPFMPVEIIL
LPKWFPFHLSKIAYWSRTVTVPLTILCSLRAQAANPRKINIRELFTVDPEEERNYFPVRT
PLNRLFLLIERTASLFEPLIPNALRRVALHRAERWVIERLNGECGLGAIFPAMVNANEAL
ALLGYPYEHSYREQSRQALLGLLIDEGEQIWCQPCTSPVWDTVLASLSLQEDIGADQKPV
RDALDWLVPLQIRDAPADWREENIKLAGGGWAFQYANPHYPDLEDTAAVAWAMHQADPHA
YRKSIKQAASWLSGMQSKNGGFAAFDVDNIYYYLNEIPFSDHGALLDPPTSDVSARCTGF
LALYGKPEQQDSMKRGLTYLFNEQEPSGAWFGRWGSNYIYGTWSVLEALRLAKVDTTHTS
IIRAVLWLKSVQREDGGWGESNDTYFEPKLAGEFETSTSFQTAWALLGLMAAGETHCEEV
HKGIKFLLHRQNNDGLWDDPWFTAPGFPRVFYLKYHGYSKYFPLWALARYQAFTQMDPV
>A0A7M2SFV6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces ferrugineus|TrEMBL
MTATTDGSTGAVPPRAAAASDTDSETPVAAGVHEAARRAAARATDFLLAKQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDEKTTRAAALFIRGEQREDGTWATFYGGPGELSTTIEAY
VALRLAGDAPDAPHMARASAWIREQGGIAASRVFTRIWLALFGWWKWEDLPELPPELIYF
PKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAHPNPPRPLAPAASW
DGAFQRLDKALHQLRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSIIALRL
LGYDLEHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALVDAGVPADHPQL
VRAADWMLGEEIVRPGDWAVRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHHDP
ERAERAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIRWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALVAAGIPGSHP
AIRRAVTWLESVQNDDGGWGEDLRSYKYVKEWSGKGASTASQTAWALMALLAAGERDSKA
VERGVEWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFAKK
PEPSLVEAKGS
>A0A6L8V9M3|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus silvestris|TrEMBL
MPVWSEVNEEIRRMRVRLEQWQQQDGSWRFCFENSLLTDAYMIVVLRTLEDPQEELIKRL
HDRIAAEQELSGAWKVYHDEADGNLDATVNAYFALLYSGYSKKTDETMMKAARFISSKGG
VKQVKTLLTKVFLATAGQYPWPSSMMIPLEFLLLPSTSPINFFDFSGFARVHFAPILIMA
DLKFVKTNAATPDLSDLTQPVRKNSESSRGFQELLNEVHSGIKQLTSLPQQLHKRAVRYA
QTYMLERIEADGTLYSYSTCTLLMILSLLALGYDKNHPTITAALKGLYSMLWNIDGRVHL
QNSPSTVWDTALLAAALQQAGTSPEHPSIAKAVRYLRSMQQSKLGDWSLHVAHPVPGGWG
FSESNTINPDVDDTTAALRAIHATTQRNPEYQDAWNRGLNWILSMQNKDGGWPAFERGVT
NKLLTLVPVDGASAAAIDPSTADLTGRTLEFLGATAGLDVHQTFVRRGADWLFSNQEADG
SWYGRWGICYIYGTWAALTGLIAVRTKPDHPAVQKAVDWLLSIQNEDGGWGESCASDSVK
HYVPLGASTPSQTAWALDALIAVCEVPVPAIHKGMRQLLQLMHKDDWTTQYPTGAGLPGS
FYSHYHSYRYIWPLITLSNYKKKYENL
>A0A6L7UXK6|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MPNSARRTTPVADTALARTIQSASNWLIEQQDEAGFWWGELESNPSITAEYLLLTHHLGI
GDRAEWDGIARYLRTQQRPEGFWAQYREGPGDISTSVEAYFALKLAGDDPDAPHMSRARE
WILEQGGIIEARVFTKIWLALFGEFDWDRLPAMPPWINLLPSWLPINLYEFASWARATIV
GITVIMALRPTAALPAGAGVPELWVRSSDRRRFAVPPPSNPFSATGALYVVDTLLRFLDR
NRIRPFEHRALAFSERWLLDRQEADGCWGGIQPPWVYAILALRAMGYSLDHPVLRRALDG
FERFTWRQEHNQGEQIWTESCQSPVWDTCLAAVGLLDAGLDPQHPALQRAAGWMLREQVL
AGGDWQIKNPDTPPGGWAFEFDNDVYPDVDDTAVVMMALERIPLPELETERQLALDRGLH
WMLSMQSSNGGWGAFDVDNDKTFLAEIPFADFGELLDPPTADVTAHALEYIGQLGYSGQY
PPASRGLRFLYDLQEPDGSWWGRWGVNYIYGLGAALPALAALGEPMSAPAVRNAVEWLFR
HQLDDGGWGESCDTYADPSLRGTGPSTPSQTAWALMALIAAGEAEHESVERGVRYLIDRQ
REDGTWDEPEFTGTGFPSDFMINYHLYRHYFPLMALGRYRSAIAPR
>A0A329QKV4|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus taichungensis|TrEMBL
MSHILSTIDEEISRMTTSLLQQQRQDGSWHFCFENGTVIDAYVIILFRILEVPNEALIRE
LHDRILNEQQKDGCWRLYTDEEDGNLSASVEAYYALLYSGYSQSTDEPIQRAKQYIQSKG
GIEKVTSILTKAILAATGQMKWPLSISMIPLEILMFPNYFPINYFEFSGYSRVHLTPMLI
MADLRFSITATHAPDLSDLTDLRNVADESTARGYQEMQNNILSGRSRMLGNPRHIHNTAR
TKAEQFMIERIESDGTLYSYASSTILMIFALLALKYDKQHPLITKAITGLTAMQCRSSGG
KTTIQNSPSTVWDTALITYALQEASLTDDHKSIQLAASYLLSRQQNKRADWSIHNPNTVP
GGWGFSESNTINPDVDDTTAALRAIRSMSTTLPTFQESWNRGLNWVLSMQNKDGGWPAFE
KNTNKEMLTWLAIDGAKSAATDPSEADLTGRTLEYLGNFAGLDTRHEWINRGTKWLIRNQ
EKDGSWYGRWGVCYIYGTWAALTGLMAVGLPANHDTVQKGVQWLLNIQNSDGGWGESCQS
DRLLHYVPLGESTPSQTAWALDTLIAVQSEPTPEMNQGILRLIASMHENDWRTTYPTGAG
LPGNFYSHYHSYTYIWPLLTLSHYRSKYGAS
>A0A6I5BUZ5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4926|TrEMBL
MTATTDGSTGAATPPATTASAPLHLSPEASEAHEATARATRRAVDFLLDRQSDEGWWKGD
LATNVTMDAEDLLLRQFLGIRDEATTQAAALFIRGEQQEDGTWNTFYGGPGDLSATIEGY
VALRLAGDSPEAPHMRKASAFVRARGGVARARVFTRIWLALFGWWKWEDLPEMPPELMFF
PKWAPLNIYDFGCWARQTIVPLTVVCAQRPVRPAPFALEELHTDPADPNPAQPAPPVASW
DNVFHKLDKMLHGYRKVAPRRVREAAMRAAATWIVERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVLRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATVALADAGVPADHPQM
IRAADWMLAEQIVRPGDWVVRRPDLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVAHPDA
TRVDKAVRRAVDWNAGMQSKNGAWGAFDADNTSPFPNRLPFSDFGEVIDPPSADVTAHVV
EMLAEEGLAHHPRTRRGIEWLLENQETNGSWFGRWGVNYVYGTGAVVPALVAAGIPAAHP
AIRRSVSWLGQVQNEDGGWGEDLRSYQDTAWHGRGHSTASQTAWALLALLAAGERDSEQV
RRGIAYLVETQTEDGTWDEPWFTGTGFPWDFTINYHLYRQVFPVTALGRYLNGTGPGEN
>A0A532CLK6|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp|TrEMBL
MNIIKALFNRLSDSLLSTVQGRLDPATELTPVASLRLVSDKPVILASLDSSAARRPIGHA
VSQPDAVDDAIRRSQSWFFNRQHAEGYWVAELEADTTLTSEYVMLRRFLDRVDLDREVKA
VRYLQATQLQDGGWPIYYGGPAEISASVKAYFALKLCGVSADEPFMVRAKDRILAMGGIL
QANVFTKITLALFDQYDWEGVPHMPVELMLLPKKFYFSIYAISYWSRAVLIPLLIVFAHR
PVCRIPREQGIDELYPIPRPEVRYWKYPPFNKDQAWFTPHNFFVALDVMLKLYDRMPMRA
LREKALHKAACWMVDHLKGAGGLGAIYPAMANSIMALQCLGYDADDPLVVKALREIEALE
VYDSTMVDGESVPTLHLQPCFSPVWDTALLMNALVEAGVPQDHPSLQEAGRYLMSRQTKA
VGDWIISSPNAEPGGWYFQFENESYPDVDDSAVVIMALSKLKIPGHEDELNESIGRGMRW
VLAMQGSDGGWGAYDKDNNRVVFNYIPFADHKALLDPSTSDLAGRCLEMLGALGYDKTHP
AAGPALAFLKKEQEEDGSWYGRWGVNYIYGTWSVLAGLRAIGEDLSAPYICRAVAWLKSK
QNPDGGWGESCLSYRDDSEVHGKGESTPSQTAWALMALMSADAVDSFSVARGVQFLLRWQ
MKDGSWEEISHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRSRGKIRADELRHHIQGT
DLYRSKH
>A0A7W1Z432|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirales bacterium|TrEMBL
PLHRDSTLLSWRNFFVWVDGLLRLYEAYPIKALRKKALKSAQTWMIEHMDGEGGLGAICP
AMAYSIYALRALGYSTDHPLVQKTLREIEALEIYSNPGNTPTPTMLHLQPCHSPVWDTAL
IINALIERGLALDHSSLRRADAWLRSRQCQKVGDWAVSAPEARSGGWAFQFENEWYPDVD
DTAAVVTGLAKIHPVELSGSDEAIQRGFRWALALQGSDGGWGAYDKDNNKLIFNKIPFAD
HQALLDPSTADLTGRCLEMLGTLGYDQSHPAVNPAIEFLRKEQEPNGSWYGRWGVNYIYG
TWCVLSGLRAIGLDMTVPWIQQAVIWLESVQNPDGGWGESCDSYAETQKAGRGESGASQT
AWALMALLQAGESDSISVVRGVNWLIRHQRENGVWEEPFHTGTGFPRVFYLRYHGYFKYF
PIWALGMYRNVKMTGEARADHLRKAAQVARHISKLV
>A0A532EQD0|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp|TrEMBL
MNIIKALFNRLSDSLLSTVQGRLDPATELTPVASLRLVSDKPVILASLDSSAARRPIGHA
VSQPDAVDDAIRRSQSWFFNRQHAEGYWVAELEADTTLTSEYVMLRRFLDRVDPDREVKA
VRYLQATQLQDGGWPIYYGGTAEISASVKAYFALKLCGVSADEPFMVRAKERILAMGGVL
QANVFTKITLALFDQYDWEGVPHMPVELMLLPKKFYFSIYAISYWSRAVLIPLLIVFAHR
PVCRIPREQGIDELYPIPRPEVRYWKYPPFNKDQAWFTPHNFFVALDVMLKLYDRMPMRA
LREKALHKAACWMVDHLKGAGGLGAIYPAMANSIMALQCLGYDADDPLVVKALREIEALE
VYDSMTVDGESVPTLHLQPCFSPVWDTALLMNALVEAGVPQDHPSLQKAGRYLMSRQTKA
VGDWIISSPNAKPGGWYFQFENESYPDVDDSAVVIMALSKLKIPGHEDELNESIGRGMRW
VLAMQGSDGGWGAYDKDNNRVVFNYIPFADHKALLDPSTSDLAGRCLEMLGALGYDKTHP
AAGPALAFLKKEQEKDGSWYGRWGVNYIYGTWSVLAGLRAIGEDLSAPYIRRAVAWLESK
QNPDGGWGESCLSYRDDSEVHGKGESTPSQTAWALMALMSADAVDSFSVARGVQFLLRWQ
MKDGSWEEISHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRSRGKIRADELRHHIQGT
DLYRSKH
>A0A7Z0Q1H7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. UH6|TrEMBL
MTATTDGSTGALPTRAGPAGTTPAGPTARPPGDGPAGPREAAALAARRATDFLLATQDAE
GWWKGDLETNVTMDAEDLLLRRFLGILDEDTAHAAALYVRGQQREDGTWASFHGGPPDLS
TTVEAYIALRLAGDAPDAPHMTRAATWVRDQGGVAATRVFTRIWLALFGWWRWQDLPELP
PEMIFLPKWFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHADPAAPLPPRPP
APATGWDGVFRRIDDALRRYRGIAPRPVRRAAMNAAARWIVERQENDGCWGGIQPPHVYS
LIALHLLGYDLGHPVMRAGIEALDRFAVRREDGARMIEACQSPVWDTCLAVIALADAGLP
ADHPQLVKAADWMLGEQVVRPGDWSVRRPQLPPGGWAFEFHNDNYPDMDDTAEVVLALRR
VRHHDPERVEHAVARGVRWNLGMQSAGGGWGAFDVDNTSVLPNRLPFCDFGEVIDPPSAD
VTAHVVEMLAVEGHADDPRTRRGVDWLLREQEPDGSWFGRWGVNYVYGTGSAVPALIAAG
LPAGHQAIRRAVRWLRSVQNADGGWGEDLRSYREPGGWAGRGDSTASQTGWALMALLAAG
EHRSEAVERGVAWLAATQRDDGTWDEPQFTGTGFPWDFSINYHLYRQVFPLTALGRYLNG
EPLAAKAR
>A0A7U8DCL8|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia mallei JHU|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANAMRVTVGM
>A0A856MJD2|squalene-hopene cyclase|EC 5.4.99.17|Brasilonema sennae CENA114|TrEMBL
MQIQDKQTVSRVKDAIAKNQNYLLSIQYPDGYWWAELESNVTITAEVVLLHKIWGTDRER
PLHKVEAYLRSQQRDHGGWELFYGDGGELSTSVEAYMALKLLGVPETDAAMVKARKFILE
RGGISKTRIFTKLHLALIGCYSWQGIPSLPPWVMLLPDNFVFNIYEMSSWARSSTVPLLI
VIDRKPVFKINPAITLDELYAEGLEQVKYELPSNGDWTDLFITLDKTFKLAETLNLVPFR
EEGIQAAERWILERQEATGDWGGIIPAMLNSLLALRALDYNPADPIVERGLRAVDNFAIE
TADTYTVQPCISPVWDTAWAMRALIESGLTPDHPAVVQAGEWLLSKQILDYGDWAIKNKK
GKPGAWAFEFDNRFYPDVDDTAVVVMALNQVKLPNEKLKQAAIARAVNWTASMQCQPGGW
AAFDLDNNQEWLNLVPYGDLKAMIDPNTADVTARVLEMLGSGNLSIDTRNQERAISYLIR
EQETEGCWFGRWGVNYIYGTSGVLSALSLIAPEKTQVSIERGAAWLVGCQNSDGGWGETC
RSYNDPALKGQGPSTASQTAWAIIGLIAAGQATSKFAKLAMEKGINYLLETQQSDGTWYE
ADFTGTGFPCHFYLKYHLYQQYFPLLALGHYQAISELW
>A0A6P0WM50|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO3A2|TrEMBL
MQTQDRIVESGVTGAIANSQSYLLAQQYPDGYWWAELESNVTITAEIVLLHKIWGTDKQR
PLHKAEAYLRSQQQKHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDSALVRARDFILR
RGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPEWFPFTIYEMSSWARGSTVPLLI
VFDQKPVFEIEPRINLDELYTEGADQVKFELPRNSDWTDLFVLLDDGFKLAEDWNLVPFR
KQGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPIVQRGLEAIDRFAIE
TPDSYRVQACVSPVWDTAWVLRAMVESGLEPDHPALVRGGEWLLQQQILDYGDWVVKNPQ
GKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLKQAAMARGLAWIASMQCNQGGW
AAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEMLGSCNLSIESQKLENAIAFLIQ
EQEADGSWFGRWGVNYIYGTSSALSALSKIAPHTHQRSIERGAAWLVKCQNLNGGWGETC
LSYDDPTLKGLGISTASQTAWALIGLMAAGEATGNWAMDAIEMGVNYLVSTQQPDGSWDE
TEFTGTGFPSHFYLKYHFYQQYFPLLALGRYQMSVAS
>A0A6B9FSH0|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium mesophilicum SR1.6/6|TrEMBL
MREAVSKVEALQRSKTQGISLDDVERGVAQATRALTALAHDDGHICFELEADATIPSEYI
LFHHFRGTQVPGDLEAKIGNYLRRTQGRHGGWALVHEGPFDMSCTVKAYFALKMIGDDIE
APHMRRAREGILSRGGAANANVFTRFMLALYGEVPWRAVPVMPVEVMFLPKWFPFHLDKI
SYWARTTVVPLFVLQATKPRARNPRGISVQELFITPPESVRRWPGSPHATWPWTPIFGFI
DRILQLVEDHMPRKRRQRAMEKARAWVSERLNGEDGLGAIFPAMVNSVLMYEVMGYRPDH
PQVRVACDAIEKLVVEKADEAYVQPCVSPVWDTALASHALLEAGGPEAEAQARAGLDWLK
PRQVLDIVGDWAARKPKVRPGGWAFQYANAHYPDLDDTAVVVMAMDRAMHQHGLVAGMPD
YKASIARAREWVEGLQSEDGGWAAFDADNNHMYLNHIPFSDHGALLDPPTADVTARVVGM
LAQLGETRETSRALDRGVNYLLNDQEEDGSWYGRWGMNFIYGTWSVLCALNAAGVDPADP
RIQRAVSWLVRIQNPDGGWGEDASSYKIDPAFEPGSSTASQTAWALLALMAAGAVDDPAV
TRGINFLTRTQGADGFWKEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKRGNSRR
VQFGM
>U5QM17|squalene-hopene cyclase|EC 5.4.99.17|Gloeobacter kilaueensis JS1|TrEMBL
MQVQPRVEKVRLERAIEASQGHLLARQSAAGYWWAELESNVTMTAEVVLLHKIWGTDGER
ALTKAAAYLLGEQRAHGGWELFYGDGGDLSTSIEAYMGLKLLGLSAAHPALVRAREFIVS
RGGISRSRIFTKIHLALIGCYDWRGIPSLPPWAMLLPAGLPVSIYELSSWARGSTVPLLV
VFDRKPVFATDPAITLDELYAEGRAEARFELPRHPDDWFANLFVDLDRVFKLSESLGAVP
WREEGVRAAERWVIERQEASGDWGGIIPAMLNSLLALRCLGYDACDPVVRRGMVAVDRFV
IETESTYRVQPCVSPVWDTALTMRALVDAGCAPDHPALVRAGEWILTQQILDYGDWSIKN
TAGPPGGWAFEFVNRYYPDVDDTAVVVMALEAVRLPDEVAKRQAMVRAERWVASMQCREG
GWAAFDIDNDAHWLNSLPYADLKAMIDPNTADVTARVLEMYGRTALTIDPQSRRRALDYL
RRVQEPEGCWFGRWGVNYIYGTSGVIAALVPFAPEERAAIERAAAWLVQCQNPDGGWGET
CRSYDDRSLMGQGPSTASQTAWALIGLIEAAHVTRMPARSAIDRGIAYLLSTQKSDGSWD
EAHFTGTGFPGHFYLKYHLYQQHFPLTALGRYRRSFG
>E2PZ48|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces clavuligerus|TrEMBL
MTATTDSDGGPLRPAATGTAADTAGRRPPVPGRPGAPGTPGLTETARWATTRSVEHLLGR
QHSQGWWKGDLQTNVTMDAEDLLLRQFLGILDARTAEAAARFIRGEQRSDGAWATFHGGP
GDLSTTVEAYVALRLAGDLPGDPHLAGASAWVRHHGGIAGTRVFTRIWLALFGWWPWDEL
PELPPELIFLPSWFPLNIYDFGCWARQTIVPLTVVSAMRPVRAAPFALDELHTDPANPRP
PRPLAPATTWDGLFQRADRTLRRHRRLVPRRLRRAALAAAARWIVERQESDGCWGGIQPP
AVYSLIALNLLGHDLDHPVLRSGIASLDRFAVWRPDGSRMVEACQSPVWDTALATVALAD
AGLPADHPALVRAAEWLLGEEVVRTGDWAVRRPGLAPGGWAFEFHNDTYPDIDDTAEVIL
ALRRVSHPDPARVDAAVARAGRWTLGMQSAEGGWAAFDADNTSPFPDLLPFCDFGEVTDP
PSADVTAHVVEMLAYEGRAHHPRARRGIDWLLERQESCGAWFGRWGTNYLYGTGAVVPAL
IAAGIPAAHPAVRRAVHWLVSVQNDDGGWGEDQRSYQEEGWAGRGASTASQTAWALLALL
AAGERDGGAAERGVAYLAGTQRGDGSWDEPHYTGTGFPWDFSINYHLYRQVFPLTALGRY
LHGEGAAAVAAPLRQGG
>A0A5D4MIG2|squalene-hopene cyclase|EC 5.4.99.17|Rossellomorea vietnamensis|TrEMBL
MEANIADQIIRLRDRLTANQKSDGSWHYCFENSLMTDAYMIVLIKSLGIKKEKVTAALAG
RLLSQQTIHGFWKVFDDEDEGNLSATVEAYFSLLWSGVVQEADENMVKARKYILSQGGLD
KAHSMTKFMLAVHGQYPWDRFFPVPIEILLLPSCFPVSFMDFSAYARVHLAPLLLLKSEK
YIRRNRMIPDISFLVTEKEGCNLFREEERTFIESVSKGLEAIAAIPADLRSVSKKTALDY
MFGRIEKDGSLYSYFSSTFYMIFALLSQGYSRNHPLVIDAIKALLSYQCKGEGFPHIQNS
TSTVWDTALITHALQASGMNSSSTPIVMANSYLFKHQHTKKGDWASEAPGTAPGGWGFSH
SNTINPDVDDTTAALRAVKFEAFQDRLKKDAWDRGVSWTLSMQNEDGGWPAFEKNKNKEI
LSWVPMDGAEDAATDKSCADLTGRTLEFLGKDAGLKMENPQVKKGVEWLIRYQEKDGSWY
GKWGICYIYGTWAAVTGMTAAGVQNEEEAIKRAKKWLYRIQNNDGGWGESCRSDKEKRYI
SLGSSTPSQTAWALDALIAASDSPTKEIQKGIEALIVLVDSEDWRTNYPTGAGLPGRFYI
NYHSYKYSWPLLTLANYRNKFIDS
>A0A7C5EY07|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Solibacter sp|TrEMBL
MMPKPYAREELATAAAGALKKGVDYLAGLQYPDGYWWGELTADTTLESDFILLQLWLYPP
EGSSWNPPTRDLVDKAVRSILARQLPDGGFNIYQKGPSEVSASVKAYFALKLAGLPMDGP
QLSRARQKILELGGIQAANSYVKINLSLFGLYPREHCPSIPPEIILLPGKFIYQMSSWTR
AIVVPLSIVHSHNPMRPVPAGFNLQELFLPGGRMKYRGGRHALSWRSLFLALDRLLKLAE
GHEPKWLRARALREAERWMLERTRYSDGLGAIYPPMMYILMAFDVLGYDRNHPDFVEAHN
QFMRLLTDDGERFFFQPCFSPVWDTAIAMFALAASGVAEQETLRRGADWLLTKEVRHKGD
WAIKRPNVEPGGWYFEFANEFYPDIDDTAMVLLALRHATASNPKAQRAAVDRALRWLLAM
QSQDGGWAAFDVDNDWTPLSEVPFADHNAMLDPTCPDITGRVMDALCAWGLTGRHDAIRR
GVAYLLRAQEQDGSWYGRWGVDYIYGTFLALRGLRAAGMGPTEAPVLRAAEWLRSIQNSD
GGWGESCASYDRNTFVPAESTASQTAWALLGLLAAGDAESSSVRRGIEYLAATQQEDGSW
HEELTTGTGFPRVFYLVYQLYRQSFPVLAISDYLRARGENSSERK
>A0A7K2ESV0|squalene-hopene cyclase|EC 5.4.99.17|Acidimicrobiia bacterium|TrEMBL
MNDHQAHQSVREAVERTQQYFLRTQRDDGCWWGELESNPTIEAEYIMLTRFLRSDEGDRT
GRVAADIRRRQQPDGSWRMYFGAPGDLSTTIECYFALKLAGDPPDAPHMAQARAFIIEQG
GIPKSRVFTKIWLALFGQWDWRATPSMPPEIMLLPKWAPFNIYRFSSWARATIVPMTIVL
TLKPTRPPPAGAGIEELRRDGPEALAVSRFKPNPLSVQGGFLLMDRALRLWRGLRLVPGR
RRALRAAVDWIVSHQEGDGSWGGIQPPWVYSLIALSALGHPLDHPVLAKGLQGFRNEWSL
PSPDGAALRVQACLSPAWDTALAMRGLMDSGVSPDHPAIQRAAEWLVGKEVRYAGDWAVK
RPHLEPSGWAFGFDNVNYPDIDDSSVIVANLALTNLADRASDSAKEATIDRAVDWLTGMQ
SSNGGWAAFDYNNDSRSVTKIPFADFGEVLDPPSADITAHMLEMYGILGYSRWHPAVRRG
LHYLWQQQEPDGSWFGRWGVNYLYGTGAVLPALEALGVDMAQPAVRKAVQWLVDTQNPDG
GWGETCESYVDPTLSGQGDSTASQTAWALIALIAAGEAATEPVTRGIEFLVATQRADGTW
DEPQFTGTGFPGYGHGDRPTKKGAPADSLQGAEMGAAFMINYHLYRNYFPLWALGRYLSA
VA
>A0A1Q8LD59|squalene-hopene cyclase|EC 5.4.99.17|Pseudonocardia sp. Ae706_Ps2|TrEMBL
MTPAHAGTGRLADEVAEAIAGGAEALLRSRRDDGVFDYGADSLRSTLATAGAVTALHFAD
PGGTADLIAAGAARLRRTQTEDGGWAMVPGLPAEPGPTAVSAAALHLVDPAGSAEQVAAG
RRWMERYGGLAAIPHPEVVLWCRQFYGFVGWIAPADMRRFPLELALLPGLYRRLFDLRLP
MASALGLAQTRHRRMTRVQRTLSRLAEPNALRVIRQTYEHEGSAGSWSEDAWVTGLVCTG
LARAGVGQDMVDAAVGWLRRSMHPDGSWATTPLDAAWTMYAVRGLVEAGYGDDERLVASR
DALLGLQQHRPFLAFGCPPGFWGWTAGRGWPAVLETGEIVSVLSRLPGTVQGAAVAEGVG
WLTDRQDSRGSWGLCVRNTRVANSGPCPTTTAQALDALLDAGVPADDRRVRRALRWLGRA
QLTGGGFESVWYREHTMGTAAVLETFARCGRGGDGPAVRARALLERTRNPDGSWGDGHGA
PGTVEETGWAVAALLAAGAAPAEVEPAVRWLLAARLPDGGWPAAPVHEYVRRVSRYANPG
FTHGMALRALGRYRKALT
>A0A7W8MQF9|squalene-hopene cyclase|EC 5.4.99.17|Edaphobacter lichenicola|TrEMBL
MGISASNPKSVDQPAQPRFGRMDVGLDRITDGVARAKDWLFEQQHPDGYWCGELEADSML
ESDYIFMHTLLGTGEPGRMERAINEILRHQNDDGGWGLFPGGPSNISYGVKAYLALKLMG
WSKDHPVLVKAREWVLAHGGVVECNTFTKIYLCALGQYDYDAVPAIPPEIVLFPNWCYFN
IYEISSWSRGILVPLSIIYAKKPFKKLAPEQGIEELFVGGRENANLHLRWDKKKPLGWRN
FFLAVDRVMHLAERVHIRPLRKVALKRAEAWMLERFEKSDGLGAIYPAMLNSIVALRCLG
RSVDDPQLIRALDEFEKLGIDCPDGTDDYSTPTFRMQPCFPPVWDTAQAMYALGEAGVRR
DDPRMLKAADWILSKEVRQKGDWAEKVKNVEPGGWYFEFNNEFYPDVDDTGQVLLALNCV
ENPRERYQYDACQRALNWIWAMQCKNGGWASFDRDNTKMIFQYIPFADHNAMLDPPTVDI
SGRMLEMLALYGVDRSDPRVEKAIQFILKEQESDGSWFGRWGVNYLYGTFLVLRGLEAMG
FWNHEPAVQQAAEWIRMVQNADGGWGETCGTYDDPNQRGIGPSTPSQTAWAVLGLLAAGD
TRSDSVAKGIRWLVDRQHEDGSWDELVPGRNGESYYTGTGFPRVFYLGYHLYKQYFPLLA
LTTYERAMKSGTAH
>T2AYK3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIIIEKAANWLVERQILDVIGDWAANAHGVRPGGWAFQY
WNDYYPDADDTAVVVMALHRADPDRYSEAIARGAEWTIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARSIVYLKRGQEVNGSWYGRWG
>T2AZN5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGLAMHAVLEANSVPDKIIMEKAANWLVERQILDVIGDWGANAHGVRPGGWASQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSW
>T2AZS1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLAMHAVLEANSMSDKTIMEKAANWLVERQILDVIGDWGVNAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVVRATGYLKRGQEVNGSWYGSWG
>T2AZ49|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKTIMGKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPIADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGRWG
>T2B083|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALNGYSLLENGSTLKDNVIEKACKWLKKRQILNVKGDWIVNNKNILPGGWAFQY
KNNFYPDVDDTAIVVMFLERAGYQNKNMISRACKWIAGMQSKNGGWGSFDKDNTYHYLNN
IPFADHGALLDPPTSDVTARCISMLSQIDKKKYKNEIKNGVDFLKKEQEKNGSWFGSWG
>T2AYJ9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGGWRIQKPELSGGGWAFQY
SNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRSGGFSSFDINNTHFYLN
EIPSADHGALLDPPTADVTGRAITLLSLADKKTYAKNIKDGVDYIKSEQEEDGSWYGRWG
>T2AYU5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAIATIALRDAGVPAEHPSLKRTVDWLLDKEVRRSGDWTVRNSETEPAGWYFEFN
NEFYPDVDDTCMVLMALARCLPNQPEWDADFLVDDWSPHEADKDVTAVLAARNADSVLAA
VQVDGLRPMLGAMHRGARWILAMQSKDGGWGAFDRDNVRKLFTQVPFADHNAMIDPSTAD
LTARMLEMFSYLNVPADHPVVRRAIDFVWKDQDPEHCW
>T2AZL3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLATHAMLEANLSSGPRILENDSTSKACKWLENLQIKDCAGDWAVWRPNLRPGG
WAFQYHNDYYPDIDDTAVVAMALHRTGDKIYEPALLRAAEWIIGMQSKNGGWAAFDADNE
YHLLENTPFADHGALLDPPSADVSARCISFLTQIGYDQTNGTIKRGIEYLKKNQEEDGSW
YGRWG
>T2B031|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAALALQEANPKATRHSREKAYNWLKTKQLDKQPGDWQIQQPHLNGGGWAFQF
ENPHYPDVDDTAVVAFAMANACDLNNLEESIHRATHWTAGMQSRNGGFGAFDCDNTDYYL
NHIPFADHGALLDPPTADVSARCAMLLGHQLNSHPEYQKTLDKTITFLRKEQESDGSWYG
RWG
>T2AZR9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVIGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGRW
G
>T2B008|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGFNGLSLLESGLTLKDSSIQKACKWLEKKQILEIKEDWIVNNKNLLPGGWAFQY
ENDFYPDVDDTAVIVMFLDRAGYQNKKKLEIACNWIIGMQSKNGGWGALDKDNTYHYLNN
IPFADHGALLDPPTADVSARCISMLSQINKKNYKKIIQKGVKFLKNEQENDGSWYGRWG
>T2AYI0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PVWDTAIATIALRDAGVPAEHPSLKRTVDWLLDKEVRRSGDWAVRNSETEPAGWYFEFNN
EFYPDVDDTCMVLMALARCLPNQPEWDADFLVDDWSPHEADKDVTAVLAARNADAVLAAV
QVDGLRPMLGAMHRGARWILAMQFKDGGWGAFDRDNVRKLFTQVPFADHNAMIDPSTADL
TARMLETFSYLNVPADHPVVRRAIDFVWKDQDPEHCWYGSWG
>A0A3G8M146|squalene-hopene cyclase|EC 5.4.99.17|Methylocystis rosea|TrEMBL
MNAAARIDANFTPISSEALETSIQNAKRALLSLGKGDGHFCFELEADTSLSAEYVLMRHF
RAEPIDAELERKIAVYLRRCQGDHGGWPLYQDGPFHISTSVKAYFALKMIGDDVDAPHMA
RARAAILAYGGAAKSNVFTRALLALYGEIPWRGVPVMPVEIMLLPKWFPFHLDKISYWGR
TVLVPMLVLMTKKPRAKNPRNIHIAELFTTPPEEVKVWPKGEHQTWPWANIFGKIDKLLR
LIEPHMPNGPRERSIELAMTWTTERLNGVDGLGGIFPSMVNSLLMYDVLGVPDADERKKQ
AREAIERLLVVHDAEIYCQPCVSPVWDTCLTAHTLLETGDEDAREQARQACEWLAPLQVL
DVKGDWAAQRPHVRPGGWAFQYANAYYPDVDDTAVVVTAMDRLTANDSSRPYDERIARAK
EWIVGMQSKNGGWGAFDADNTCHYLNHIPFADHGALLDPPTADVSARCVSMLAQLGDTID
SSECLKRGVDYLLKEQEKDGSWFGRWGANYIYGTWSTLCALNAVGLPHDHDAYRRAVAWL
VAIQNEDGGWGEDLSSYKLDYKGYEKSPSTASQTAWALLALMASGDVDHPAAAKGIAYLQ
STQNGAGLWNEARFTATGFPRVFYLRYHGYGKFFPLWALARYRNMRRANSKRVQVGL
>A0A4R4MC20|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. 7K534|TrEMBL
MTAVETGRRTRTAAEALEAAREHLLLLQSPEGWWKGELQTNVTMDAEDLLLREFLGIRTG
ADTDETARWIRSRQAPDGTWATFHDGPPDLSTTVEAYVALRLAGDPPDADHMLRAAAFVR
GAGGVPATRVFTRFWLAMFGRWPWDELPVLPPEMMFLPRWFPLNVYDWACWARQTIVPLA
VVGAMRPVRPLPFELDELAPFEDAPRSRKRGLPGWDTAFETLDRALHVYERRPVRGLRRA
ALRRAGDWIIARQERDGSWGGIQPPMVYSLIALHLLGYGLDHPVVRRGLDGLERFTIRDA
QGRRIEACQSPVWDTVLAMNALADAGLPEGHPALERAAEWVIGEEVRGPGDWAVRRPDLP
PGGWAFEFDNDCYPDVDDTAEAVIALNRVRHPLAEPAIERGVRWMAGMASRDGGFGAFDA
DNTRGLCRRLPFCDFGEVIDPPSADVTAHVVEAMAHRGMADSLTVKRAVVWLLKAQEPDG
SWFGRWGANHVYGTGAVVPALIAAGVRPGRPEIRAAVEWLELHQRDDGGWGEDLRSYRDP
SWIGRGVSTPSQTAWALLALLAAGERGEAVERGVGWLAEHQRADGTWDEDHFTGTGFPGD
FYINYHLYRLVFPLSALGRYLKGE
>A0A849R0M3|squalene-hopene cyclase|EC 5.4.99.17|Methyloglobulus sp|TrEMBL
MFTDANSESQTHTTESTSTAIVFKDGQLDVAIKKAQDKLLSFQDKAGYWVFDLEADCTIS
AEYIMMMHYLGEIDEPLQAKIANYIRSRQSADGSYPLFTHGPGEISCSVKAYYALKMAGD
SIDAPHMARLRTYILGQGGAAKANVFARIALAIFKQLPWRGVPFIPPEIMLFPKWFPFHL
DKVSYWSRTVMVPLFILCSLKATAKNPNNINVLELFVTHPDEEQHYFPERTLLNKIFLGL
DKFGRWAEPFIPKKIHDHAIGKAKNWTIERLNGEDGLGCIFPAMVNAYEALMLLGFPKDH
EYVVTARKAIDKLLVVSEDSAFCQPCVSPVWDTALTALALQEADKTGNAKNLTNAYNWLK
SVQLSDEPGDWRVSRPDLAGGGWAFQYANPHYPDVDDTAIVAFAMADSNLPNLDESIHRA
TRWIEGMQSKNGGYGAFDVDNTYYYLNEIPFADHGALLDPPTADVSARCAMLMAKAGKDQ
GQYQLALERAINYLRSDQEADGSWFGRWGTNYVYGTWSVLLGLEQTNLPKTDAMYVKAVK
YLKSVQHEDGGWGEDNYSYHDISYSGKYHFSTAFQTAWAVLGLMAAGEVRSPEVKAGIDF
ILRTQQADGVWNDNCFTAPGFPKVFYLKYHGYDKFFPLWALARYRNELKQ
>A0A7V8NW25|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Acidoferrum panamensis|TrEMBL
MATDTSMMLTPKVPNAELERSIELASKALLDCQQPDGHWVFELEVDATIPAEYVLLKHYL
GERDELGIESKIAGYLRRTQRAEGGWPLVYNGVFDLSASVKAYFALKMIGDRPDAEHMKR
ACQAILDHGGAARANAFTRVLLALYGILGWNNVPAMPVEIMLLPTWFPFHLSKISYWART
TIVPLLVLQALKPKARNPRGVRIDELFLDPPETARRGSKAPHQTWRWFLLFEAIDAVLRA
AEPLFPKASRQRAIKKAVAFVRERLNGQHGLGAIFPPMANSVMMFDVLGYPKDHPDVKMA
RASIDKLLVIKQEEAYCQPCLSPVWDTALTCQTLLEVGSERAVTEAVRGLRWLEPLQVLD
VVGDWGERRPHVRPGGWAFQYVNPYYVDLDDTAVVVMAMDRAAKLAETGRPQFHDAIARG
REWIVGMQCRNGGWAAFDADNTCYYLNNIPFADHGALLDPPTPDLAARCLSMLAQLGERP
ESSAVMGRAIEFLRREQRPEGCWFGRWGINYIYGTWSALCALTAAGIDPMSSMVRRAVGW
LTSIQNPDG
>A0A3N8PUE7|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia contaminans|TrEMBL
MNDLTEMATLAAGAVPAGVDTAVARATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPNYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANSVMMYDALGYAEDHPNRAI
ARKSIEKLLVVQDDEAYCQPCLSPVWDTSLAAHALLETRDARAEDAAIRGLEWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAVAMERAQQLKQNDAYRDSIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGIDYLI
AEQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNTTRVTVGL
>A0A2L0X3J2|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus metallidurans|TrEMBL
MTRKTIPASELDAAIVRARDALLDRQHPDGHWCFELECDATITAEYILMMHFVDEIDTAL
QARMAKYLRAVQRLDGHGAWDLYFGGDLDISCSVKAYFALKAAGDPPDAPHMVRAREAIL
ARGGAAKSNVFTRILLATFGEIPWRGTPFMPVEFVLFPRWAPIHMDKVAYWARTTMVPLL
VLCSIRAAAKNPLGVHVQELFVTPPELEREYFPRKRGLQQAFLVADRVVRHLEPLIPRAL
RRRAIQRAVEWSEARMNGEDGFGGIFPPMVYSYEMMVLLGYPEDHPLRVECKAALKKLVV
HRDDGSSYCQPCLSPVWDTAWSVMALEQAPPDARTETAIARAYDWLTDRQVLDLRGDWEN
NAAPNTPPGGWAFQYENPYYPDIDDSAVVLAMLHARGKRTGQPGRYEMPVARCLDWIIGL
QSRNGGFGAFDANCDRDFLNAIPFADHGALLDPPTEDVSGRVLLALGITERPQDATARER
CIQYLRDTQQPDGSWWGRWGTNYIYGTWSVLAGLGLAGVDRKLPMVRNGLQWLRGKQNTD
GGWGETNDSYARPELAGKHEDGSMAEQTAWAMLGQMAVGEGDADSVHRGAAYLLDAQNED
GFWMHPYHNAPGFPRIFHLKYHGYTAYFPLWALGRYRRLAAARASAMQKTKAESTESAES
MTVH
>A0A7V3QEC9|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MYGPAEQVDIVPRVEIGSVSIEELTRVISSGIRWLGEKQSAEGFWVGFLQSNSCMEAEWI
LAMHFLGVRGDPKLPGVVKAILNEQRADGSWEVYYDAPEGDINATVECYAALRCAGFKPD
DEPLRRARTWILEHGGLSRVRNFTKYWLALIGEWPWDSTPAVPPELIFLPRWFPLNIYWF
ASWARATIIPISILSALRPVRPLPPESRLDELFPQGRQNFTHKIAKRGRGLGPTFFVLGE
RLCTYYTKLPFHPLRETAIRLCVEWIIRHQDWDGAWGGIQPPWIYSLMALNAAGYPITHP
VLQKGLDAWNHHWSFKRGEAIYLQASESPVWDTLLTLQALLDCGETFETFSGMRKAVEWV
LSKQIFTPGDWSYTVKGVECGGWAFERANIYYPDIDDTAVAVQVLSRIRQIAPSDLRKRI
EFAVDRAVKWLFAMQSSNGGWAAFDRDNNHWIMAEIPFCDFGEVLDPPSVDVTAHVLEAL
GSVGYKLNHPAVQKAVEFIFREQERDGSWFGRWGVNYIYGTSAVLSGLQAVGFPMNDPRV
IKAADWLASKQNPDGSWGESCASYMDDTMRGCGPSTPSQTAWAILGLINVRSPKYTRNIL
QGVQWLIQNHTGGTWSEKHYTGCGFPGYGIGERIRYKRNTFLLAQGRELSRGFMINYNMY
RHYFPLQALGRVRLWLQRSQGS
>A0A6L3NNG8|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia territorii|TrEMBL
MIRRMNKPAPSHWSALDTAIARGRDALMRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDARQAQMARYLRAIQRLDTHGGWDLYVDGDPDVSCSVKAYFALKAAGDSEHAPHMVRA
RDAILKLGGAARANVFTRILLATFGQVPWRATPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNIAIPELFVTPPDQERQYFPPARGMRRAFLALDRVVRHVEPL
LPKRLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMEVLGYPDDHPLRRDCENAL
EKLLVTRPDGSVYCQPCLSPVWDTAWSTMALEQARGVATPESGTPAGTLDELDARITRAY
DWLTERQVNDLRGDWIENAPADTQPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRAHRNA
DGSHPYAARVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRPDDRASLSRAVDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALAGED
PSQPYIARALAWLRARQHADGGWGETNDSYIDPALAGTNAGESTSNCTAWALLAQMAFGD
CESDSVKRGIAYLQSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
AASSSSEANGSCEPASRTTDATPA
>A0A4Y9SYS0|squalene-hopene cyclase|EC 5.4.99.17|Massilia horti|TrEMBL
MGHSNFSCLPNAPADLPPSLVEEAIGRAMDAVLAEQRPDGHWVYELEADATIPAEYVLMV
HYLGEPADLLLEAGIGRYLRRIQGQDGGWPLFHGGALDVSASVKAYFALKMIGDAPHAPH
MARARAAILAHGGAECSNVFTRLLLALFGQVPWCAVPHMPAEIALLPYWSPFHLSKVSYW
TRTVVMPLLVLTTLKPRAKNPRGVRIDELFIEAPGRLGMATKAPHQSAAWFALFRSLDAH
LRTFDKRTPRSLRRRAIERAASFVRERLNGEDGLGAIFPAMVNAVQMLDALGVPRDSQEA
MTARRAIDKLLVRRLDECYCQPCLSPVWDTALMCHALLECGQPAALEATCRALNWLKPLQ
VLDIRGDWCVRRPTLRPGGWAFQYANPHYPDVDDTAVVAMAMHRAGMLAPMLDFGDALAR
ATEWVVGMQGRGGGWGAFEPENTHLYLNNIPFSDHGALLDPPTADVSARCLSMLAQLQGK
PGKHSPAARALGYLLREQEKDGSWYGRWGMNYIYGTWSALCALNAAGVAHDAAPVSRACA
WLAGVQNLDGGWGEDGTSYRLGYDGYEPAASTPSQTAWALLGLMAAGATGHPAVARGIRW
LVERQRPDGLWDEAHYTATGFPRVFYLRYHGYARYFPLWALARYRNLRGQGSRRVAFGM
>T2AZK7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDSEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSW
>A0A7W3VX70|squalene-hopene cyclase|EC 5.4.99.17|Amycolatopsis dendrobii|TrEMBL
MTQTVPRTSASAPAARTAAETVGAAVEFLRREQDRAGWWKGELATNVTMDAEDLLLRHFL
GILTPQIAEESARWIRSQQRSDGTWANFPDGPADLSTTVEAWVALRLAGDPADAPWLATA
ADWIREHGGIEATRVFTRIWLAMVGQWSWDDLPSLPPELIFLPSWFPLNVYDFACWARQT
IVPLTIVGTLRPVRKLPFDVSELRTGKRPPKTRAPWTWDGVFQNLDTALHAYAKLPLNPV
RKLAVKQAAEWILARQEADGSWGGIQPPWVYSILALHLLGYSLDHPALKAGIAGLDGFTI
REKTDQGWVRRLEACQSPVWDTALAMTALLDAGVSPGDETLVRAADWMLGEEIRVPGDWA
VRRPSLQPGGFAFEFANDGYPDTDDTAEVVLALRRMGKPDHLRIREAVDRSVAWLEGMQS
SDGGWGAFDADNTQVLTTRLPFCDFGAVIDPPSADVTAHVVEMLAAEGKSGTRECRRGIR
WLWDNQEEDGSWFGRWGANYVYGTGAVVPALVAAGVPGSDPRIRRAVKWLAEHQNDDGGW
GEDLRSYDDRAWAGRGDSTPSQTAWALLALLAAGERESTAVTRGVEWLVERQRPDGGWDE
DKHTGTGFPGDFYLSYHLYRVVFPLSALGRYARGGS
>A0A7W4NXC2|squalene-hopene cyclase|EC 5.4.99.17|Gluconacetobacter aggeris|TrEMBL
MMVNATDTLERPSADGAGLAVPMIEIDQAVDAGHAALGRRQNDDGHWVFELEADATIPAE
YVLLEHYLDRIEPALEARIGVYLRRIQGDHGGWPLYHGGRFDLSASVKAYFALKAIGDDI
NAPHMARARAAILDHGGAERSNVFTRFQLALFGEVPWHATPAMPVELMLLPRKAFFSVWN
MSYWSRTVIAPLLVLAALRPRAINPRDVHVPELFVTPPAQVRDWIRGPYRSPLGRVFKYV
DKVIRPGERLIPEATRRRAIKAAVDFIELRLNGVDGLGAIYPAMANSVMMYRALGMPDSD
PRAATAWESVRRLLVEHGDEAYCQPCVSPIWDTGLAGHAMIEAASGPEGVRPEETKKKLA
AAARWLLDRQILNVKGDWAINCPDVAPGGWAFQYNNDYYPDVDDTAVVGMLLHREGDPAH
HEAIERARQWIIGMQSTNGGWGAFDIDNNMEFLNHIPFADHGALLDPPTADVTARCVSFL
AQLGRPEDRPVIERGIAYLRTDQEAEGCWFGRWGTNYIYGTWSVLCALNVAGVSHDDPAI
VGAVDWLRSVQREDGGWGEDCATYEGATPGIYTESLPSQTAWATLGLMAAGLRDDPAVAR
GMAYLARTQKEDGEWDEDPYNAVGFPKVFYLRYHGYRQFFPLMALARYRNLESSNTRRVA
FGF
>E6VJ84|squalene-hopene cyclase|EC 5.4.99.17|Rhodopseudomonas palustris (strain DX-1)|TrEMBL
MDSGSYDTGVGRNALEASIDAARSALLNYRRDDGHWVFELEADCTIPAEYVLLRHYLGEP
VDAELEAKIATYLRRIQGAHGGWPLVHDGDFDMSASVKGYFALKMIGDSIDAPHMVRARE
AIRSRGGAIHSNVFTRFLLTLYGVTTWRAVPVLPVEIMLLPNWSPFTLTKISYWARTTMV
PLLVLCALKPQAKNPKGVGIDELFLQDPKTIGMPAKAPHQNWGLFKLFGSIDAVLRVIEP
LMPKWLRQRAIDKALAFIEERLNGEDGMGAIYPPMANAVMMYEALGYPEDYPPRASQRRG
IDLLLVDRGDEAYCQPCVSPVWDTALASHAVLEADGHDGAKSVRPALDWLLPRQVLDLKG
DWAVKAPNVRPGGWAFQYNNAHYPDLDDTAVVVMALDRARKDEPNPAYDSAIARAREWIE
GMQSDDGGWGAFDINNTEYYLNNIPFSDHGAMLDPPTEDVTARCVSMLAQLGETVHSSPA
LARAVGYLRDTQLAEGSWYGRWGMNYIYGTWSVLCALNAAGIAHSDPMIRKAVAWLESVQ
NRDGGWGEDAVSYRLDYRGYESAPSTASQTAWALLALMAAGEVDNPAVARGIEYLKTTQT
EKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLQATNSKVVGVGM
>A0A521K1X9|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
MKLIRSLITRLSDSLFASVPDRLKAGARTRLGPVLRLVSHNLYPSAAPEQPRRAAGPAHG
QSEAIDEAMRRSQAWLLGRQHPREGYWVAELEADTTLTSEYLMLRRFLNLVDPDRERKAV
LYLRTMQLPEGGWPIYYGGPPEISASVKAYFALKLSGVSADEPCMVRGREAILGMGGVVA
ANVFTKITLALFDQYDWRGIPSMPPEIMLLPKRFYFSLYAVSYWSRAVLIPLLIIFSHRP
VCRIPKEQGIDELFLQPREQVRFRHEPPLKRDAAWFTWRNFFVTVDRALKVYDRMPIRSL
RDKAVAKAAEWMLDHMKGAGGLGAIYPAMANSVVALRCLGYGVDHPLVVKAFGEIEALEI
YDVVPEGKGGAETLHLQPCHSPIWDTALLLNVLAEAGLPQDHQALTKAATWLLSRQTTTV
GDWKVSAPDAEPGGWYFQFENELYPDVDDSAVVLMGLAKVRMADREAQRQAMARGYRWVM
AMQGSDGGWGAYDKDNNRMVFNLIPFADHRALLDPSTADLAGRCLEMLGALGYDRTHPAA
VRALNYLRHEQEPDGSWFGRWGVNYIYGTWSVLAGLRTIGEDMSAPYVERAVAWLESKQN
PDGGWGESCLSYADRDMAGRGVSTPSQTAWALLALLSAGVTNSITVVRGVHYLLRHQRED
GSWEEVRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRAHGQTRADELRRIARETGRF
RAEG
>A0A3P0NTJ6|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp9017|TrEMBL
MIRRMNRPASSPWSALDTAIARGRDALARLQQPDGSWCFELESDATITAEYILMMHFMDR
IDNARQERMARYLRAIQRLDTHGGWDLYVDGAPDVSCSVKAYFALKAAGDSEHAPHMVRA
RDAILKLGGAARSNVFTRILLATFGQVPWRAAPFMPVEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNIAIPELFVTPPDQERHYFPPARGMRRAFLALDRLVRHVEPL
LPKRLRQRAIRHAETWCAERMNGEDGLGGIFPPIVYSYQMMDVLGYPEDHPLRRDCEHAL
EKLLVTRPDGSVYCQPCLSPVWDTAWSTMALEQARGVAAAEAGEPAAAHELDEHIARAYD
WLAGRQVNDLRGDWIENAPADTQPGGWAFQYANPYYPDIDDSAVVTAMLDRRGRTHRNAD
GSHPYAARVARALDWMRGLQSRNGGFAAFDANCDRLYLNAIPFADHGALLDPPTEDVSGR
VLLCFGVTRRADDRASLARAIDYVKRTQRPDGSWWGRWGTNYLYGTWSVLAGLALAGEDA
SQPYIARALAWLRAQQHADGGWGETNDSYIDPALAGTNGGESTSNCTAWALLAQMAFGDS
ESDSVKRGIAYLQSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLAG
AKDAGTTASSASGTPGVPATRATDSALA
>A0A7K2WJT7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID3212|TrEMBL
MTATTDGSTGAVGPRAAAASEPTDTTTAAAGDLLVAARRATARSVEHLLGQQDAQGWWKG
DLETNVTMDAEDLLLRQFLGVQDPRTTEAAGLFIRGQQRADGTWATFYGGPPELSATIEA
YVALRLAGDSPDDPHMKRAATWVREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELIF
FPKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDAGAPNPVKPLAPVAS
WDGMFQRLDKVLHAYHKVAPRRVRRTAMNAAARWIIERQENDGAWGGIQPPAVYSVIALH
LLGYDLDHPIMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVSPDHPA
LVKAADWMIAEEISRPGDWAVRRPELAPGGWAFEFHNDNYPDIDDTAEVILALRRVRHPA
PARLDAAVERGTRWTLGMQSRNGAWAAFDADNTSPFPNRMPFCDFGEVIDPPSADVTAHV
VEMLAYEGMAQHPDTRRGIEWLLAEQEASGAWFGRWGVNYVYGTGSVVPALTAAGLPVTH
PAIRRAVRWLESVQNDDGGWGEDLRSYREEKWIGHGVSTASQTAWALLALLAAGGRESAA
VERGVAWLAETQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPLASG
AISRKGS
>A0A7V5GXQ9|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Acetothermia bacterium|TrEMBL
EKGFSIEEDDTFRLQSCLSPVWDTGLAMIALEDAGLGSDHPALVKAGEWLLKEQIFAGGD
WQMRCNGRPGGWAFEFANDIYPDTDDSSVVMMALQRAKLEAKRKAHALDRGLEWLLAMQS
SNGGWGAFDRNNTKAFLRQIPFADFGEMIDPPSVDVTAHIVELLGQLGYRAGFPPLDRAL
RYLKREQEPDGAWFGRWGVNLTYGIGYVLPALAAVGEDMSSPYVRRAIDWLIAHQNEDGG
WGERIEGYVDEEWRGRGPSTPSQTAWALLGLIAAGEIDHPATLGGIQYLIATQREDGGWD
QPYFTGTGFPVDFMINYHLYRDVFPVMALGRYRNAKRGELETRGSGDTEREEN
>A0A7V9P792|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MSATVTSALDRTLSAAVERLVELQKSGGWWVGELESNVTMTAQHAFLLHFLRLLDEETLR
RVANELLARQRPDGTWAIYRGGEPNLDATVEAYAALRLAGLGPEDPRLAEARSFVVARGG
IGAARVFTRIWLALLGLWPWREVQLVPPEIVLLPPAAPLSVYSFACWARQTMVALSVVTA
YRPVRPVPPDRACRELDLGPVTRPRTAWQGLDRAVARYNERPLGPLRERALARAERWLLD
RQELDGSWGGIQPPWVWSLVALACRGHGLESPYLRRGIAGWKRFVVDDGERIRFEACQSP
VWDTALAVLALSTSGMSPASPALAGAVEWLLREEIGARGDWALRRPGVEPAGWAFEHDND
LYPDIDDTAVLALGLEELGMGAEAVDRARRWLAGMQSSDGGWGAFDVDNTGRWLNCIPFF
DFGAVTDQPSADVTAHVVEFLARDPRHDETVRRGVDYLLREQEPDGSWFGRWGVNHVYGT
GAVLPALDAARVSRSNPAVRRGVAWLERVQNDDGGFGEDCRSYDLGEAGLAWRGRGESTP
SQTAWALLALAAAGETRTPVAQRAVGWLAATQRADGDWDEEPFTGTGFPRDFMIRYHLYR
IVWPVLALARVRHALEAE
>F8GT07|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus necator (strain ATCC 43291 / DSM 13513 / CCUG 52238 / LMG 8453 / N-1)|TrEMBL
MSMNETAFATAVPRIAPASAGDSPSPRGAAQALDHGIGRAIDALLHQQRPDGHWVYELEA
DATIPAEYVLMVHYLGEAPDLELEARLARYLRRIQNPDGGWPLFHEGRSDVSASVKAYFA
LKMAGDDPQAAHMQRARRAIHALGGAEASNVFTRTLLALYGVMPWSAVPMMPVEIMLLPQ
WFPFHLSKVSYWARTVIVPLLVLNSLRPQARNPRGVGINELFVGNCHTVRLPPRAAHQHA
GWYTVFRGLDALLRVAEPLVPRTLRRRAIAAAQAFVRERLNGEDGLGAIFPAMANSVMMF
DVLGVPPDDPARAVARQSIERLLVEHGDEAYCQPCLSPVWDTALAAHALLETGEARATAA
AGRGLDWLRPLQVLDVRGDWIVRRPRVRPGGWAFQYANPYYPDVDDTAVVAAAMDRYMRA
HDVPGRYDEAVARAAEWIVGMQSSDGGWGAFEPENTHLYLNNIPFADHGALLDPPTADVS
ARCLSMLCQIGATPGKSEPAARALRYLLAEQMPDGSWFGRWGTNYIYGTWSALCALNAAG
LAPEAPEMRRAVAWLEQIQNADGGWGEDGSSYRLDYRGYEPAPSVASQTAWALLALMAAG
AARHPAVARGIDYLLRTQQSGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWALARYRNL
QRGGAHQVSWGL
>A0A8I1YIX7|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium elkanii|TrEMBL
MLARDHSVAVDPVALEKSISKATEALLGYRQSDGHWVFELEADSTIPAEYILLRHYLAEP
IDAGLEAKIGNYLRRVQGAHGGWPLVHDGPFDMSASVKSYFALKMIGDSVDAPHMVRARE
AIRSRGGASGSNVFTRFLLALYGVVTWRATPVLPIEIMLLPMWSPFHINKISYWARTTMV
PLMVLAALKPCAKNPKGVGIDELFLEDPKSVRMAPKAPHQSPSWFYLFRSLDAVLRVIEP
MFPKRLRQRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYEALGKDESFPPRAITRRG
IDKLLVVGEHEAYCQPCVSPVWDTALASHALQEAGGDDTLAKAKQGLDWLKPRQVLELKG
DWAVKAPDVRPGGWAFQYNNDHYPDLDDTAVVVMAMDRVRRHTGTREYDEAIARGREWIE
GLQSRDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLGQLGETAESNRA
MADGVAYLRRTQLAEGSWYGRWGLNYIYGTWSVLSALNVAGVDRNDPMIRKAVDWLASVQ
NQDGGWGEDAVSYRLDYKGYEVAPSTSSQTAWALLGLMAAGEVENPAVARGVEYLKATQT
EKGLWDEQRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNSRVVGVGM
>A0A5N9H7L1|squalene-hopene cyclase|EC 5.4.99.17|SAR202 cluster bacterium|TrEMBL
MGLYETQPFHPFRKLAEKRLLNWVLTHQENDGLWAGIQPSTFYSLIALYSLGFDVGDPVM
QKGLSGVDRLCWESNEDMAVQGCISPGWDTALGLLTLLESGIDVETEVIYKSIIWLLSNQ
VTINGDWIMNAGNVSPGGWAFEFHNNNYPDIDDTALVIMGLTKAYSYGLELSEIRDSIRQ
GLGWVLGLQSRSGGWAAFDKDNCSKYLSDLTFSDFGEVIDPPTVDVTGHVLEMLGNLGCS
MEDVHVNRACQFVQDNQEPDGSWFGRWGVNYIYGTGCVLPGLAAIGEDMCEPYIVRAAEW
LVDHQNEDGGWGETCGSYADPSLRGVGPSTASQTSWALIGLIASCHKADDSIYRGIQYLM
DTQQQDGTWDEPYFTGTGFPGYGTGCAPYGIQQDELWCEYDLSIPSGLMIRYDLYRIVWP
LLALARYKQSCTQ
>A0A3R9VMY0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. WAC07061|TrEMBL
MTATTDGGGAITDGADPRHETTTAPAATAVGPSGGGTGLPTGVREAVDRAVGELLARQDP
AGWWKGDLQTNVTMDAEDLLLRQFLGIRDEAVTRAAALFIRGEQRDDGTWATFHGGPPEL
SATIEAYVALRLAGDPPDAPHMTRASAWIRAHGGIAAARVFTRIWLALFGWWSWDRLPEL
PPELVFLPPWVPLNIYDFGCWARQTIVPLTVVSALRPVRRAPFALDELHADARDPSPAKP
LAPLASWDGAFQRMDKALHLYRRVAPRRLRKAAMAAAGRWIVERQENDGCWGGIQPPAVY
SVIALHLLGYDLGHPVMRAGLESLDRFTVWREDGARMVEACQSPVWDTCLAAIALADAGL
PPDHPALVKAADWMLGEEVRRPGDWAVRRPGLAPGGWAFEFHNDNYPDIDDTAEVVLALR
RIRHPEPGRVEAAIARGVSWNLGMQSKNGAWGAFDADNTSPLPNRLPFCDFGEVIDPPSA
DVTAHVVEMLAAEGRAADPRTRRGIAWLLAEQEPEGPWFGRWGTNYVYGTGSVVPALTAA
GIAPSHPAVRRAVRWLESVQNEDGGWGEDQRSYRDRSWAGRGASTASQTAWALMALLSAG
ERDGDAVARGLAYLVETQRPDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHG
EPFGPQRRSVPAAGES
>A0A533ITS5|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium icense|TrEMBL
LGKDENFPPRAITRRGIDKLLVIGEDEAYCQPCVSPVWDTALTCHALAEAGDAESLAKAK
QGLDWLKPRQVLDLKGDWAVKAPNTRPGGWAFQYNNAHYPDLDDTAVVVMAMDRERRRTG
SHEYDTAIARGREWIEGMQSRDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARC
ISMLAQLGETAQTSKAMADGIAYLRRTQLPEGSWYGRWGLNYVYGTWSVLCALNVAGVDH
GDPMMRKAVEWLVSIQNRDGGWGEDAVSYRLDYRGYEQAPSTSSQTAWALLGLMAAGQVE
HPAVVRGVEYLKSTQTEKGLWDEQRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLSNT
NSRMVGVGM
>A0A523K5Z5|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MLDKIRDKQSEAEESVRDDSVLTETPGTLEETIQTARDALIAQQQADGHWVYQLEADCTI
PAEYILMNHFADEIDDELELKIAVYIREHQADHGGWPLFYGGDFDLSCSVKSYYALKMVG
DDPHDEHMVNARNAILQHGGAAHANVFTRILMAIFEQVPWRATPFIPAEVILLPKWFPFH
IDKVSYWSRTVMVPLFVLCTLKAKAVNPRAVDIRELFTTPPEEEQHYFRITTPLTRAFLI
LDHVGKLFEKLVPKFVRNISVRKCEKWFTERMNEEHGIGGIFPAMVNVYESLIILGHDKN
SALVKQARKAIDNLLVHGDDQTYCQPCMSPVWDTALACQTLLEIQENNELDETTTKIKDG
LDWLKEKQLSDEPGDWRIPCPDLEGAGWAFQYSNYYYPDLDDTAMVAWAMHRTGDETYSE
AIYRAAIWVDGMKSKGGGFGSFEVNNTQYYLNAIPFADHGALLDPPTADVTGRCIALLTL
ANKTKYEHTITNAIDYLKKDQEQDGSWFGRWGTNYIYGTWSVLTALELAEEDPQQAYIRH
AISWLEDIQNDDGGWGESNESYYPPKHRRPNASTSYQTAWSLLALLAVGKVNSEAVQRGI
QYLLDELNANGLWDDPDYTAPGFPRVFYLKYHGYTKYFPLWALARYNNLNKQS
>A0A534HKE3|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MQPSAPALASGRLEWPVRRELATVNRGSPTRGSSAVAPNAARADAPAHKIHRLTEFSPLD
RSIAAARDALISLQSSQGYWLFELEADCTIPAEYVLMTHFLDEIDASLEPKLAAYLRARQ
AEHGGWPLYHGGDFDMSCSVKAYFALKLAGDSPQAPHMVRARAAILQRGGAARCNVFTRI
TLALFGQIPWRGVPYIPVEIVLLPRWFPFHLDKVSYWSRTVMVPLLILCTRQPAASNPRK
VQIRELFTTPPEEERHYFRRPGGREGVLSRAFLALDRLGRMIDPLIPKALRAYATRRAQG
WMLERLNGEHGLGAIFPAMVNALEALAVLGYATSDAPRVAAKRALEKLLVVNASSAYCQP
CVSPVWDSALASLALQETGGAAALAASVRALDWLQPLQLLDNPGDWRVRRPQLAGGGWAF
QFSNAHYPDLDDTAVVAWSMHQAGDPARYAHNVQCALDWLVGMQSHNGGFASFDVDNTHY
YLNEIPFADHGALLDPPTSDVTARVVTVLARVGRPQDQAVLARAIAFLRQEQEADGSWFG
RWGTNYIYGTWSVLTAFAQAGIGPDDPATRRAVSWLTARQNADGGWGESNDTYAYGQLAA
GKSPSVPHQSAWALLGLLAAGEAGTDAVRRGVEYLLRTQQDDGLWSDPSFTAPGFPRVFY
LRYHGYCAYFPLWALAAYRTLIRRGTTH
>A0A3N2P747|squalene-hopene cyclase|EC 5.4.99.17|Micromonospora sp. HM5-17|TrEMBL
MSGLLSPGGAPAGPETGGHPEASETRRTAGIPAPLWDQARAALDRARDLLLSRQQPEGWW
QGELETNVTMEAEDLLLREFLGIRTPEVTEPTARWIRSKQGADGAWATFYGGPGDPSTTI
EAYAALRLAGDPPEAEHLRRARQFILAHGGIERSRVFTRIWLALFGEWSWHRLPAIPPEV
VFLPPRFPLNVYDFACWARQTIVPLAIVRSLRPVRPLGFSLRELRTGQRPERPPSLRRRA
GWMHRLDAALRRYERHPIGPVRRTALRRAAEWVIARQEADGSWGGIQPPWVYSLIALHLL
GYPLSHPVLKAGLAGLERFTVHEETPDGPVRRLEACQSPVWDTALAVTALADAGVSAGHP
ALDRAARWLLAEEIRVPGDWAVRRPGLAPGGWAFEFDNDGYPDTDDTAEVLLALRRTGAD
PAVRAAVARGVAWLRGMQSADGGWGAFDVDNTRAIARDLPFCDFGEVIDPPSADVTAHVV
EALCAEGLADSAAVRRGVAWLRRHQEADGSWFGRWGANHVYGTGAVVPALIAAGVPRDDP
AVVRAVCWLHRRQNPDGGWGEDMRSYRDPSWRGRGVSTASQTAWALLALHAARTDDIGSV
SRGLRWLVETQRPDGGWDEPQYTGTGFPGDFYINYHLYRLVFPVSALGRLLADPGWPGVV
PAAPAELTAEVGPAAPAEPTGAVGPTGAAQLATRAEATARTELADRVAPAGGSDGGAGPA
GGRGRTELVDQGESS
>A0A7C3H6K3|squalene-hopene cyclase|EC 5.4.99.17|Bryobacterales bacterium|TrEMBL
MDSVWFENVNRRVTRRTVSVAAATRQSLAQACTQTLQRAGQALLDLQKPEGHWCGDLLAD
TTLESDYILLQLWLHPPDSAGWNPPTKARIEKAARSILRRQLPGGGFDIYPGGPPDPSAS
VKAYAALKLAGVDPASPEMTRLRQCILDLGGVQAANSYVKINLSLFGLYPREHVPTIPPE
LVLLPGGVLYEMSSWTRAIVVPLSIVQARGGTRPVPPGFHLNEIVAPGKSFRLPRRDKLS
FLFYGIDRGLKIWQDRGNARVKNAAIRAAEKWMLDHTRYSEGLGAIYPSMMYLIMALDAL
GYPRDHPDLIDAIRQFEALLTDRGDEFYFQPCFSPVWDTAYAAFALGEMGQVPEDRLRRA
ADWLIAREVRRKGDWSVKRPDLEPSGWAFEYANEHYPDIDDTAMVLLALLHARATDREAQ
ARCERRAVNWLIGMQSKDGGWAAFDVDNDWQLLNKVPFADHNAMLDPTCPDITGRVLESL
CRRGLVHSHPTVRRGVDYLLKTQERNGSWYGRWGVDYIYGAFLAMRGLKYSGAPNVQEAV
RKGARWLAAVQNPDGGWGESCASYLEDRFVPAPSTPSQTAWALLGLLAAGESYYDGVRRG
IEFLIETQQADGTWKEDLATGTGFPNVFYLRYTLYSRYFPILALTMARRALGRDEPEVLH
AAAGLPG
>A0A4R4VNZ8|squalene-hopene cyclase|EC 5.4.99.17|Saccharopolyspora terrae|TrEMBL
MTEQLQQPTRSATSAAEIPSQGAARADARTAALAARDHLLSLQSPEGWWKGELETNVTMD
VEDLLLRQFLGIRTSAETAETARWIRSQQREDGTWATFHGGPGDLSTTVEAYAALKLAGD
DVEAPHMRAARDWILASGGVEGTRVFTRIWLALFGEWSWDDLPAMPPEVVLLPEWCPLNV
SDWACWARQTVVPLTVVCTLRPRRDLGIDLRELRTGRPAVPPKREWSWGYGFHALDRLLH
RYHRRPVKTLRTHAMRRAAEWIVARQEADGSWGGIQPPWVYSILALHLLGYPMDHPVIAK
GLGGLERFLVREQTPEGTVRRLEACQSPVWDTVLGVQALRDAGVPADHPSLRRAVDYLLA
EEIRVKGDWSVKRPELPAGGGWAFEFDNDGYPDIDDTAEVLLALNRVEHPDSDAVRGAIA
RGVRWLRGMRSKDGGWAAFDADNTRQLVRKLPFCDFGEVIDPPSADVTAHVVEALAVLGE
QDEVLRGGVKWLLSNQERDGSWFGRWGANHVYGTGAVVPALVAAGVDCQHRALRDAVRWL
EEHQNDDGGWGEDLRSYDDPQWIGRGTSTASQTGWALMALLAVGRHDTDAVRRGIGYLAR
SQRADGGWDEPQFTGTGFPGDFYINYHLYRVIFPLTALGRYLRDGE
>A0A838Q727|squalene-hopene cyclase|EC 5.4.99.17|Chthoniobacterales bacterium|TrEMBL
MPGDAPAYAPETSDIREAISRAQRNLLRQQQPDGHWCGELLVDSTLCSDYVLFMHWLGEV
DDTLQQRCVRHILKRQLPDGGWNIYFKGLSEVNASVKAYFALKLAGHSADLPFMQEARAN
ILRLGGIPRMNTFSKLYLALLGQFPWQYLPSIPVEMVLLPAWMPFNIYKMSSWSRAMLVP
LAIINHFKPTRELPGLQQLHELYPLGTEHKDFTLARDARLLTWRNFFLRGDHALKIISKI
GWRPMRQRALEEAEHWMLERIGEGSDGLATVFPAMLNALIALKALGYPPTHPAYEKALGD
FRGLFVDDPEDFRIQPCLSPVWDTAINLIALAESGVPAEDPVLRKAAAWLVDKEVHLRGD
WTINNRHPEASGWAFEYNNVYYPDTDDTAMVLTALRLVRPSSAEGLKKLFKRALDWQLSF
QCKDGGWAAFDKEVTQHWLEDMPFADHNAILDPTCSDLTARTLELLGYIGFDRKQPCVRR
AVQYLIDTQDDDGSWYGRWGVNYIYGTWQVLRGLRAIKEDMSQTWILRGRDWLESCQNDD
GGWGETCASYDDPTLKGRGESTASQTSWALMGLCACGDLDRPSVQRGLRYLLSTQRSDGA
WNESEITGTGFPGVFYLKYDMYRQNFPLLALATYVNYRSGIGHRPSFYRCTV
>A0A850JD63|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. BRA 177|TrEMBL
MTTTEAPGLTGAAAAAADAARGHLLGLQSPEGWWKAELETNVTMDAEDLLLRQFLGIRTE
SETADAARWIRSQQRPDGTWANFHGGPADLSTTIEAYVALRLAGDPVDADHMLAAAKFAR
DAGGIEGSRVFTRIWLALFGQWSWDDLPVMPPELMFLPSRVPLNVYDWACWARQTIVPLT
ILGSLRPVRPLPIDLAELRSGVTPPDDAKGWGRAFNTLDRVLHVYEKTPVRPLRRAALRR
AADWIIARQEADGCWGGIQPPWVYSLMALNVLGYDLGHPVIRRGLDGLERFTIRDEQGRR
LEACQSPVWDTVLAMNALGDSGTPPDDPALRRAARWIVDEEVRGPGDWSVRRPDTPPGGW
AFEFDNDVYPDTDDTAEAILALRKVAFPEASEPIERAIQWLNGMASRDGGFGAFDADNTR
ELCTKLPFCDFGAVIDPPSADVTAHVVEALAKEGLAETTVVKRAVVWLLKAQEADGSWFG
RWGANHVYGTGGVVPALIAAGVRPEKPAIRRAVAWLEEHQNPDGGWGEDLRSYDDPAWIG
RGESTASQTAWALLALLAAGERSAAVDAGVRWLVQNQRPDGNWDEDQFTGTGFPGDFYIN
YHLYRLVFPISALGRYLEGVT
>L8EUJ7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces rimosus subsp. rimosus (strain ATCC 10970 / DSM 40260 / JCM 4667 / NRRL 2234)|TrEMBL
MTTTADDAPREKGPLPAAEEEAARRAVRRAADHLLSRRHTGGWWEEEFTTDVSYDAHDLF
LRHVLGILDERVATAGGRWIRSQQSADGSWPLVFGGAGHLGTTVQAYVALRLAGHRPDED
HMGRCAAWVREQGGVAAAPLEAHVWLAMCGLWCWDDLPEIPPEIIALPTWAPLNIYAFSS
IMRQALVSLGVISAYRPVQPVPFGIDELFVPSDGTPVRPVSAPITRWAGVFQRANTVLRA
GRRITPRAVRRIATNMCARWLLERQETDGSWGACTPITTWVTLALHLHGYAPDHPVLKAA
LRFLDESASWPEDDMRKLRTVRSPVWDTGLAVTALLDAGLDAGHPALVGAADWLLARQSD
RPGDWTARRPRLAPGGWAFQFHNRTYPDNDDTSEVVLALLRIEHPDRARVDDAVRDAVRW
CLGMQSADGGWAAFDVDNASALPGKLPFFDFGEYCVDAPTADITAHVVEMLAAAGMADDP
RTRRAVQWLLGRQEDDGAWFGRWGVNHVYGTGCVLPALIAAGTPCGHPAVRRAVTWLTSV
QNDDGGWGEDWESYADPGRVGRGPSVPSQTAWALLALLAAGERDSAAVRSGVRWLTGRQT
DDGTWEEPEFTGVLVPRAVACRYGYYRHVFPLMALGRYVHRRDAAATR
>A0A7X3QYN1|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
AIDRVLHAHERLPWKPLRDFSLKECERWIIEHQEADGTWGVIQPPSVYSLIALRAHGYSM
DHPIMQKGLNGFLGDFALRRGNTFSVQPCLSPVWDTALAVTGLREAGVPADDESLVQAGR
WLLAHEVQSLGDWALTVPGIEPGGFPFEFSNELYPDTDDTAEVLIALRLLDLRGKDGPFH
RSKVWLRAMQSTNGGWGAFDRDNNDEFVSRIPFADFGATFDPPTEDVTAHILEAFALDGT
PPSDEMMDRALDYLWDTQEPDGSWWGRWGVNYLYGLGAAVPALVAAGVDPADPRLRRAVR
WLEHHQQPDGGWGESCATYEDPSLRGQGPSTASQTAWALLALLAVEPPDHPATVRGIDYL
VRTQTDDGEWIEPHFTGTGFPRDFMLKYHLYSNYWPLWALGRYRRLRDGNPIHLPETDPL
G
>A0A3N8E4X2|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp9125|TrEMBL
MNPIPFFSPSALDAAIVRGRDALLHLQQPDGSWCFELESDATITAEYILMMHFMDKIDDV
RQAQMARYLRAIQRLDTHGAWDLYVDGAPDISCSVKAYFALKAAGDSEHAPHMVRAREAI
LKLGGAARSNVFTRILLATFGQVPWRATPFMPIEFVLFPKWVPISMYKVAYWARTTMVPL
LVLCSLKARARNPRNVSIRELFVTPPDEERRYFPPATGMRKLFLTMDRVVRHVEPLLPKR
LRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMEVLGYPDDHPLRRDCENALEKLL
VTRADGSMYCQPCLSPVWDTAWSTMALEQARGASAATQDTRVPDHELDARIARAYDWLAT
RQVNDLEGDWRENARRGTQPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRAQAHVSGKDP
YAERVARALDWMRGLQSRNGGFGAFDADCDRLYLNAIPFADHGALLDPPTEDVSGRVLLC
FGVTRREEDKAARARCIEYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALSGEDKSQPY
IVRALDWLRARQHADGGWGETNDSYADPHLGGTNYGESTSNYTAWALLAQMAFGDWQSDS
VRRGIAYLLSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLAGAQSA
PPARDSGTANAIADQAVA
>A0A800G7K7|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
MPVRPENRPVNQATQWAVHKSQEYFRQSQYAEGYWWGELESNPTMEAEYLMLCHFTGHHD
LERWRKVCNYILSKQRDDGSWGQYYESPGDVSTSVECYFALKLAGHSPNSEPLQKAREFI
LSKGGIPQVRVFTKIWLSLFGQWDWKGTPNMPPEMIYLPAWAPFNIYEFASWARATVVPM
LIILTRQPYCPVPEAANIDELYPGGRAGTDYDLPKPKTKLGWAKALYWSDKMVGLYQRLP
FHPFRGQAERKILKWVLEHQEADGSWAGIQPPWVYSLIALHTMGYGPEHEAVKKGFEAFE
VFVREDEDHCSVQACISPVWDTCIAQLALLESGIAADDPMVQSSARWLMDKQIFVGGDWQ
VRAKKTRPGGWSFEFDNLAYPDIDDASIVVMALDKVKLPDNEEPRRADSIQRGVEWMAGM
QSKNGGWAAFDKDNNKKYLTKIPFSDFGETLDPPSVDVTAHLLEMYGRLGYTKDDPAVAR
GFKYVISEQEEDGSWFGRWGVNYVYGIGAVLPALEAIGEDMSQGYIRRAVMWLLIHQNEN
GGWGESCGSYVNSNLRGVGPSTASQTAWALLGLVAAKDHGCEAAQKGLLYLAETQRNDGT
WDEPYFTGTGFPGYG
>A0A0K2G895|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira moscoviensis|TrEMBL
MKLIKALFSRLSDSLLSNGAAKLSPAPDFSPTPPLRLVSDKPTMLPPLDAATTRRPPTHA
VSQPDAIDDAIRRSQSWFLARQHPEGHWVAELEADTTLTSEYLMLRRFLDCVDPERERKA
VQYLKAMQLPDGGWPIYYGGPAEISASVKAYFALKLSGVSADEPCMVRAKDRILAMGGVV
QANVFTKIALALFDQYDWEGIPHMPVELMLLPKKFYFSIYAISYWSRAVLIPLLIVFAHQ
PVCRIPREQGIEELYPIPRQEIRYWRFPPFNKDQNWFTAHNFFVALDALLKIYDRMPLTI
LREKALHKAATWMLERLKGAGGLGAIYPAMANSIVALRCLGYDMDDPLIVKALREIEELE
VYDSASVDGQRVPTLHLQPCFSPIWDTALLINALVEGGMPADHPALLKAGSYLMSRQTKT
VGDWKISSPNAEPGGWYFQFENEFYPDVDDSAVVLMALSKLRMPEPALHREALQRGMQWV
VAMQGSDGGWGAYDKDNNRIVFNYIPFADHKALLDPSTSDLTGRCLEMLAALGYDKSHPA
VKPALAFLKREQEADGSWYGRWGVNYIYGTWSVLAGLRAIGEDLSAPYIRRAVTWLESKQ
NPDGGWGESCLSYADEAYSGKGESAPSQTAWALMALMSAGVTDSFCVARGVQYLLRHQLK
DGSWEEVRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRSRGKMRADEVRQHVQGAGS
YRFDR
>A0A6B2WYN5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID13726|TrEMBL
MTATTDGSTGALPPRAAAASETRLDTPVAAGVQEAAVRAVQRATDHLLARQDSQGWWKGD
LETNVTMDAEDLLLRQFIGIRDEATTRAAAKFIRGEQREDGTWASFYGGPGELSTTIEAY
VALRLDGDAPDAPHMAKASAWIRARGGIAAARVFTRIWLALFGWWKWEDLPELPPELIYF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHADAAAPNPAKPLAPVASW
DGAFQRLDKALHQLRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLEHPVMRAGLESLDRFAIWREDGSRMIEACQSPVWDTCLATIALFDAGVPADHPQL
VKAADWMLGEEIVRPGDWAVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHHDP
ERIERAIGRGVRWNLGMQSKNGAWAAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLSHDPRTRRGIDWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALTAAGLPASHP
AIRRAVAWLEKVQNDDGGWGEDLRSYKHVKEWSGRGASTASQTAWALMALLAAGEMDSKA
VERGIEWLASTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFSRT
EAL
>A0A2X0IST0|squalene-hopene cyclase|EC 5.4.99.17|Streptacidiphilus pinicola|TrEMBL
MTASPDGRLDPQYEAEPAAEGTTTESETTRLARETLAKATTHLLGLQDETGWWKGNLETN
VTMDAEDLLLRQFLGIRTEEQTRATADWIRSQQGEDGTWATFYGGPSELSTTVEAYVALK
LAGDDPEAPHMKRASRWIREQGGIAATRVFTRIWLALFGWWPWERLPELPPEVIFLPRNF
PLNIYSFGCWARQTIVPLTVVSAHRPVRPAPFALDELHTDPANPYRPRPSAPAYTWDGFF
HRLDKALHYYHKMPVKALRRLALQQAARWIVERQEADGCWGGIQPPAVYSLIALHLLGYD
MDHPVMKAGLNAFDRFTVHTDEGHRWIEACQSPVWDTCLALTALADAGLPADHEALVRAT
DWLLGEEVLRRGDWAVQRPGLPAGGWAFEFDNDNYPDIDDTAEVVLALRRVAHPEPGKVA
GATRRGIDWVLGMQSKNGAWAAFDVDNTSTLPNKLPFCDFGEVVDPPSADVTAHVVEMLA
ADGKAGDPRTRRGIDWLLKEQEQDGSWFGRWGTNYVYGVGSVVPALVAAGLPTEHRSVRR
AVAWLEEKQNADGGWGEDMRSYQDKSWAGRGTSTASQTAWALMALLAAGESGEVVDRGVR
WLAETQLPEGTWDEPEFTGTGFPWDFSINYNLYRLVFPVTALGRYLHGTPHLTPSELDLD
ARAVLPLPTGGASDAPAPRRLLPSLAGRRLR
>A0A7X3HLV1|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus sp. SW-Y-13|TrEMBL
MTSQAIPAADLDAALVRARDALLAQQHPDGHWCFELESDATITAEYVLMMHFVDEIDTDL
QARMARYLRATQRLEGHGAWDLYLGGDVDISCSVKAYFALKAAGDSPDAPHMVRAREVIL
ARGGAAKSNVFTRILLATFGEVPWRATPFMPVEFMLFPRWAPIHLDKVAYWARTTMVPLL
VLCAMRAQARNPLGIHIQELFVTPPELEREYFPRKRGLQGAFLKLDRVVRPLEPLIPRVV
RRRAIARAVKWSEERMNGEDGFGGIFPPMVYSYEMMVLMDYPEDHPMRRDCRDALKKLIV
HRDDGSAYCQPCLSPVWDTAWSLMALEQAPASERSAAAITRAYDWLTERQVLDQSGDWDQ
NATPGTRPGGWAFQYANPYYPDVDDTAVVLAMIHAHARRTNQEARFKPHVDRAMDWSIGL
QSKNGGFGAFDANCDRSYLNAIPFADHGALLDPPTEDVSGRVLLALGVTNRPQDKSVRER
CIDYLRQTQQRDGSWWGRWGTNYIYGTWSVLAGLALSGVDRQQPMVRRAVEWLRAKQHHD
GGWGETNDSYIDPALAGTHVFGSMADQTAWGLLGQLALGEQKSDSVRRGVEYLIRTQQAD
GFWMHPFHNAPGFPRIFHLKYHGYTAYFPLWALGRYRRLVVGKSVVSQPVCAPLPRSGRG
GPASSGFEVKPAPAFARPALPRTAVWTPPRVRQTLA
>A0A7X0DJK2|squalene-hopene cyclase|EC 5.4.99.17|Rhodanobacter sp. MP7CTX1|TrEMBL
MNPSSPAASAALASLLQETEAAASLDRAIERARVALLAQQREDGHWCFELESDCTITAEY
ILMMHYMDEIDGLLQQKMARYLRAIQATDSHGGWSQYHGGAIDVSCTVKAYYALKAAGDD
PAAEHMRQAREAVLARGGAAKCNVFTRILLALFEQVPWRAVPYVPVEIMLFPRWAPFHID
KISYWARTTVVPLTILCSLKAKAANPHKVGVRELFVTSPEQERHYFLRGGALNRAFLTLD
KVGRALDRWMPKSLRQRAIRAAEAWFLPRMNGEEGIGAIFPPMVNCYEAMALLGYPKDHP
ARQTCLRSLQKLVVHRSDGSAYCQPCVSPIWDTGWCALTLMHTSNDTSTQAAIARACDWL
TARQELEHKGDWVARAPDAAPGGWAFQYANAFYPDIDDTAVIAALLHIQDRRRAEPGRHR
FNTDRAADWMIALQSKNGGFAAFDADNTYYYLNAIPFADHGALLDPPTEDVSGRVLACLG
ILARTQDRDSLRRCIDYLRATQLADGSWWGRWGSNYIYGTWSVLGGLALAGEDARQPYIR
KAIDWLRSRQHANGGWGETNDSYIDPALRGTNQNVSTPHSTAWAVLSQLALGEVHAESVR
RGIAFLLADQQAHGLWSHPSHNAPGFPRVYYLKYHGYAAYFPLWALTRYRQLLQLTEPCA
K
>A0A522ISN9|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia sp|TrEMBL
MNDLSHAMPAGDLAGGFATAVADPLDASVARATDAILAVQKDDGHWVYELEADVTIPAEY
VLLVHYLGETPNRELEQKIARYLRRTQLPQGGWPLFTDGAMDVSASVKAYFALKTIGDAE
DAEHMVRARDAILAAGGAEAVNVFTRVMLALFGVVSWYAVPIMPVEIMLLPEWFPFHLSK
VSYWARTVIVPLLVLNAKRPLAKNPLNVRIDELFHRAPVTTGLNKRAPHQSKGWFSFFRA
VDGALRVADPLVPNYLRQRSIDAAVAFVDERLNGDDGLGAIFPAMANAVMMYDVLGYPPE
HPHRAIARQSLEKLLVIHEDEAYCQPCLSPVWDTSLAAHALLETGDARAEAAARRGLEWL
RPLQILDVRGDWISRRPEVRPGGWAFQYANPHYPDVDDTAVVVMAMQRVDLLDKTNAYGE
PIARAREWVVGMQSSNGGWGAFEPENTQYYLNNIPFSDHGALLDPPTVDVSGRCLSMLAQ
LGELPDASEPARRAYNYILEDQEPDGSWYGRWGMNYIYGTWTALCALNAAGIPHDEPRMK
RSVEWLVKIQNDDGGWGEDGASYKLEYRGYERAKSTASQTAWALLGLMAAGAVNHPAVAR
GIEWLQKTQCEDGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRSGETRVT
VGM
>A0A6N9TY68|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces halstedii|TrEMBL
MTATTDGSTGAANLRAVTFGDPIEPTTDTDDVLAAARRATGRSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETVQAAARFIRGEQLGDGTWNTFHGGPPDLSATIEAY
VALRLAGDLPDDPHMLRAAGWVRDQGGIAASRVFTRIWLALFGWWKWEDLPELPPELMFF
PSWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPEHPAPPRPLAPAASW
DGVFQRLDKALHVYHKVAPRRLRRVAMNAAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLEHPVMRAGIASLDRFTVWREDGSRMVEACQSPVWDTCLATIALADAGVAPDHPAL
VRAADWMLGEEIVRPGDWSVRRPQLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDQ
PLVDAAIERGVRWNLGMQSRDGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLATDPRTRRGIQWLLDEQEESGAWFGRWGVNYIYGTGSVVPALITAGLPASHS
SVRRAVSWLESVQNDDGGWGEDLRSYQEEKWIGHGASTASQTAWALLALLAAGERESRVV
ERGVTWLAETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFAAAA
TGTAAGREA
>A0A428KVG0|squalene-hopene cyclase|EC 5.4.99.17|Bacillus canaveralius|TrEMBL
MHELDQEIERLIHVLKEQQKEDGSWGYPFETGIITDAYMIILLRSLKIDDEEELIKALVK
RIERKQEENGAWKLYKDEQGDGNLSLTIEAYYALLYSGYRNEHNPAILAARKFIYENGGL
KKAGMYTKIMLATTGQYSWPAFFPIPIETVLLPASFPINKFDISVFGRVNLVPILLLANA
KYQRKTVLSPNLQSLNFRTNNDDDWEEFQSREWQICYSSLKNAFNSILELPAQLHKKALN
RAESFMLERREPDGTLYSYFSSTFYMIFALLALGYAKNDQIIEKAVNGLKNMACRIDDDI
HMQYTTASVWNTSLISYTLQEAGLPHQDESVRRANRYLLSRQHHKYGDWQIHNPNVEPGG
WGFSDVNTINPDVDDTTASLRALYESTKRDETARNSWQKGLDWTLTMQNDDGGWAAFERN
VNKKLLHLLPIQGAEFILTDPSSPDLTGRTLEFLGRYVSLANPKHTIGRTINWLLNNQRH
DGAWYGRWGICYIYGTWAAVTGLTSAGVPNGHQAIKKAERWLISIQNEDGGWGESCNSDI
HKKYVPLGTSTLIHTAWAADALLSISEEETPEIKKAIAYLVSEGTKQDWTIDYPTGQGMA
SFFYIHYHSYRYIWPLLTLSRYRKKFMSTLS
>E3IYF6|squalene-hopene cyclase|EC 5.4.99.17|Frankia inefficax (strain DSM 45817 / CECT 9037 / EuI1c)|TrEMBL
MSLTSDPSPATPATQPTSARPGSLSDRRSRSGGSAVAGPVLVTTRPVAPVAKSGAVTPTA
TSGAVTSTATSGPALLPDLATDLADPTGPLAGAASATVRAAGGAGTRTQQTGQLGSTELA
GPQADQVADRAAAVLGRARDHLLGLQSEAGWWKGELETNVTMDAEDLMLRQFLGILPPEL
AAETGRWIRSKQQDDGGWPTFHGGPSDLSTTFEAYVGLRLAGDLPDAPHMLAAASFVRAH
GGLAATRVFTRIWMALFGEWPWDEVPVLPPELVLLPSWVPLNVYDFGCWARQTVVALTIV
GHFRPVRSLGFSIDELRVAAVRPDRAPLVSWTGVFQRLDAGLRRYQRHPVKTLRELALRR
ATEWVLARQEADGGWGGIQPPWVYSIMALHLMGYSMDHPVLVAALDGLETFTVREQVREG
DEVVTVRRLEACQSPVWDTALAVVALADAGLDARHPAMRKAGEWLVREEVTVPGDWRVRR
PNLEPGGWAFEFANDIYPDVDDTAEVVLAVRRLLGSGWDDVDPTFAKQARASVERAVNWS
VGMRSANGAWGAFDADNVRELATKIPFCDFGEVIDPPSADVTAHMVEMLADLGRADHPVT
QRAVRWLLDDQEPGGSWFGRWGVNHVYGTGAVVPALISAGVAADHPAIRSAVRWLVAHQH
PDGGWGEDLRSYQDDAWVGRGEPTASQTAWALLALLAADPMNEAVGRGVRWLCDTQLPNG
TWDEPYYTGTGFPWDFSINYHLYRLVFPLTALGRYVTLTGRSAA
>A0A7T6VKX5|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia anthina|TrEMBL
MNDLTDMANLSAGTTPAGLDAAVASATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELERKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKSVEKLLVVHEDEAYCQPCLSPVWDTSLAAHALLETGDARAEDAAMRGLDWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLRHTDTYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSDPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGIDYLI
ARQNDEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGI
>A0A556UTG3|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus campinensis|TrEMBL
MNQAATITRPEFTATDALAASVNRLAQPALPDPLDAGIAHAVDTLLAQQQADGHWVYELE
ADATIPAEYILMVHYLGEQADPVLEGKIANYLRRIQNADGGWPLFHAGASDISASVKGYF
ALKMAGDDPEAAHMRRARAAIHGMGGAEASNVFTRTLLALYGVMPWQAVPMMPVEIMLLP
QWFPFHLSKVSYWARTVIVPLLVLNSLRPRARNPRKIGIDELFLRPAQSTRLPARAPHQS
PLWVGVFRALDAVVRVAEPLFPRSLRARAIERARTFTVERLNGEDGLGAIFPAMVNSVLM
FDVLGVPASDPDRAIARRSIDKLLVVRDDEAYCQPCLSPVWDTSLASHALLEVGEPRAIA
AAARGLDWLVPLQELNLKGDWIVRRPDVRPGGWAFQYANAHYPDVDDTAVVAAAMDRADK
GDRTDRYKTAVARACEWVVGMQSSNGGWGAFEPENTHLYLNNIPFADHGALLDPPTADVS
ARCLAMLCQLGQMPANSEPAARALRYLLDEQEADGSWFGRWGTNYIYGTWSALCGLNAAG
IGANAPEVQRAARWLLSIQNPDGGWGESGDSYKLDYRGYERAPSTASQTAWAMLGLMAAG
AGDHPAVVRGVEFLLRTQASHGFWDEPYFTAVGFPRVFYLRYHGYARFFPLWALARFRNL
LREGNHAVAWGL
>A0A0P0EWA7|squalene-hopene cyclase|EC 5.4.99.17|Azospirillum brasilense|TrEMBL
MQDHNASTTLRVQRAEPSAKAVSDAVAEATDALIRRQQADGHWVFELEADATIPSEYLLL
HHILDEIDPELEAGLAAFIRGRQGKDGGWPLFFGGAMDISCSVKAYFALKAAGDSPDAPH
MCRAREAILARGGAARCNVFTRILLAQFGQIPWRAVPAMPVEVMNLPPWSPFHISRISYW
SRTVVVPLLVVMAHRLRARNPRGIGIAELFTEPPERVRNWHSNNNRGGWATLFRALDAAL
HAVEPRLPANGRQTAIDRAVRFVTERLNGEDGLGAIFPAMVNAVLMFHCLGMPADHPDAA
TARRALRGLVVRQPGRVYCQPCLSPVWDTAIICNALLETGSPLARAAARRGADWLIDRQI
LDVEGDWAWQRPGLASGGWAFQYNNAHYPDTDDTAMVVMALQRLDADRYGEPIRRARDWI
VGMQSRNGGWGAFDAENQHDFLNHIPFADHGALLDPPTSDVTARCVMMLARLGEGRDTVP
TRRGLTFLEREQESDGAWFGRWGTNYVYGTWSALEALNAAGVPHSAVAVQRAAQWLLTHQ
RADGGWGEDGASYWAGNPRGEGAVSTASQTAWALLGLMAAGKGNHPAVDRGIEYLLSARD
AEGLWSEEPFTAVGFPRVFYLKYHGYAASFPLWALARYRALRA
>A0A7Y6SWW0|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. 41S5|TrEMBL
MLSRDHGVAVDPVALEKSISKATEALLGYRQSDGHWIFELEADSTIPAEYILLRHYLAEP
VDAALEAKLGNYLRRVQGAHGGWPLVHDGPFDMSASVKSYFALKMIGDSVDAPHMVRARE
AIRSRGGASGSNVFTRFLLALYGVVTWRATPVLPIEIMLLPMWSPFHINKISYWARTTMV
PLMVLVALKPRAKNPKGVGIDELFLEDPKSVRMAPKAPHQSASWFYLFRSLDAVLRVIEP
MFPKRLRQRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYEALGKDENFPPRAVTRRG
IDKLLVIGDDEAYCQPCVSPVWDTALTCHALQEAGSDDTLAKAKQGLDWLKPRQVLELKG
DWAVKAPNVRPGGWAFQYNNDHYPDLDDTAVVVMAMDRARRHTGTREYDEAIARGREWIE
GLQSRDGGWAAFDANNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLGQLGETAESSKA
MADGIAYLRRTQLAEGSWYGRWGLNYVYGTWSVLCALNVAGVDRNDPMIRKAVDWLASVQ
NQDGGWGEDAVSYRLDYKGYEVAPSTSSQTAWALLGLMAAGEVENPAVARGVEYLKATQT
EKGLWDEQRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNSRVVGVGM
>A0A345XLT2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces armeniacus|TrEMBL
MTATADGSTGAVPPRVRAEERDGAPGIRTGTGEQDGPRALAERTSARAVEHLLVRQHDEG
WWKGDLETNVTMDAEDLLLREFLGIRDEHTTAAAARFIRSEQRPDGTWATFHGGPGELST
TIEAYVALRLAGDEPDAPHMAAASAWVREHGGVAGSRVFTRIWLALFGWWRWADLPELPP
EIIYFPKWFPLNIYDFGCWARQTIVPLTVVSAHRPVHPAPFALEELHRDPACPNPPRPRA
AANTWDGVFQRLDAALHTYRRFAVRRLRRAALRDASRWIIERQENDGCWGGIQPPAVYSI
IALWLLGYDLDHPVIRAGLESLDRFAVWRDDGSRMIEACQSPVWDTCLATIALADAGLPE
DHPALVKAADWMLGEQVVRPGDWSVRRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALNRV
RHADPVRVDGALRRAIRWTLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADV
TAHVVEMLSHNGHRNHPANRRALAWLLSEQEENGAWFGRWGVNYLYGTGSVVPALVAAGL
PASHSSVRRAVSWLESVQNEDGGWGEDLRSYRDPEWIARGESTASQTAWALLALLAAGER
NTKAVERGIGFLARTQREDGAWDEPYFTGTGFPWDFSINYHLYRMVFPVTALGRYLRDGV
GRGGRDS
>A0A7K2JH68|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5910|TrEMBL
MTATTDGSTGAALPSRAAAASETADITSPAAAGVHEAAARATRRATDFLLSRQDAEGWWK
GDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELSATIE
AYVALRLAGDAPDAPHMAKAAAWVRTQGGIAAARVFTRIWLALFGWWKWEDLPELPPELI
WFPTWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPARPNPPRPLAPAA
SWDGAFQRIDKALHAYRRVAPKRLRRAAMNTAARWIVERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHP
QLVKAADWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVSHH
DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSRFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAVEGLTHDPRTRRGIQWLLAEQEADGSWFGRWGVNYVYGTGSVVPALAAAGLPAS
HPAIRRAVSWLESVQNDDGGWGEDLRSYRHVKEWSGKGASTASQTAWALMALLAAGERES
KAVERGVAWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFA
KAPRTVQALAESLTEAKGS
>A0A8J6ZDR1|squalene-hopene cyclase|EC 5.4.99.17|Fortiea sp. LEGE XX443|TrEMBL
MRTQDRVQVNKVADAIAKSQEYLLSMQYPAGYWWAELESNVTITAEVVLLHKIWGTDKTR
PFHKIETYLRSQQRQHGGWELFYDDGGELSTSVEAYMALRLLGVPATDPAMMRARDFILQ
RGGISKTRIFTKLHLALIGCYDWRGIPSLPPWVMLLPPAFPVNIYEMSSWARSSTVPLLI
VCDNKPVFLVDPTINLDELYAEEVDQVQYELPRQGDWTDLFLTLDQGFKLAESLNLVPFR
QEGIKAAEKWILERQEVTGDWGGIIPAMLNSMLALRCLGYDSADPIVERGLQAIDNFVIE
TEDNYCVQPCVSPVWDTAWVIRALIDSGFAPDHPAIVKAGEWLLQKQILDYGDWAVKNPQ
GKPGAWAFEFDNRFYPDVDDTAVVVMALDAAKLPNESLKQAAIARALNWVASMQCRAGGW
AAFDLDNDQEWLNAIPYGDLKAMIDPNTADVTARVIEMLGACNLSIEPRNLERALSYLLA
EQEPEGCWFGRWGVNYIYGTSGVLSALALINPQKYQQNIERGAAWLVGCQNSDGGWGETC
RTYNDPSLKGQGRSTASQTAWAIIGLIDAGEATGKFSKEAIARGIDYLVSTQKSDGTWFE
SDFTGTGFPCHFYLKYHMYQQYFPLIALGRYQAIKLKQEFSKK
>A0A4Y6UKD7|squalene-hopene cyclase|EC 5.4.99.17|Swingsia samuiensis|TrEMBL
MADVDRAVDGAHAALGNLQKEDGHWVFELEADATIPSEYVLLEHYLDRIDPEKENKIGVY
LRRIQGEHGGWPLYYGGNFDLSASVKAYFALKIIGDDLNADHMRRAREAILAHGGAARSN
VFTRIQLALYGEVPWSATPVMPVELMLLPRTAFFSIWNMAYWSRVVVASLLVLSALKPKA
INPKDVHIPELFVEPPAQVKDWIKGPYRSVWGRVFKHLDTALRPILPLIPKKIHEKAIQE
AVKFIEPRLGVGGLGAIYPAMANVIMMYRAFGVPDTDARVVKAWQAIQDLLVTKEDEIYC
QPCVSPVWDTGLSGLAMLEAASGLNPQKREETINKLKKSAEWLRKKQILDVKGDWAINAP
NVRPGGWAFQYENDYYPDVDDTAVVGMLLHRLDPKENQEAIERAREWIIGMQSTNGGWGA
FDIDNDLEALNHIPFSDHGALLDPPTADVSARCVSFLCQLGHPEDRPVIEKGIEYLRKEQ
EKEGCWFGRWGTNYIYGTWSVLCALNIAGISYNDPMIRRAVTWLKDVQRSDGGWGEDCAT
YEGTAPGVYKESLPSQTAWAVLALMAVGERDSEMVKKGIQFLKDQQDENGEWHEEPYNAV
GFPKVFYLRYHGYKQFFPLMALSRYRNLLSSNSGRVEYGF
>A0A7W7SXA0|squalene-hopene cyclase|EC 5.4.99.17|Micromonospora polyrhachis|TrEMBL
MTGLLSTAGAKPVEPTAGRSATTTATTERPDDDLRPRAEAALARAREHLLSRQQPEGWWQ
GELETNVTMEAEDLLMRQFLGILTPAETDPTARWIRSRQHPDGGWATFYDGPSDLSTTIE
AYAALRLAGDGVDAEHMVRARDFVLANGGIERSRVFTRIWLALFGEWSWHRLPAIPPEVV
LLPSWMPLNVYDFACWARQTIVPLAIVRAQRPVRPLGFSLTELRTGARPPRAPSLRGRAG
WLHGLDAALRGYERRPIGLLRRNALRRAAEWVVARQEADGSWGGIQPPWVYSLLALHLLG
YPLDHPVLRTGLAGLDRFTVREETPDGPVRRLEACQSPVWDTALAVVALADAGLPAEHPA
LVRAGRWLIDEEIRVTGDWAVRRPGLAPSGWAFEFDNDGYPDTDDTAEVLLALRRTAPGP
QVGAALERGLRWLCGMQSRDGGWGAFDADNTRTLARSLPFCDFGEVIDPPSADVTAHIVE
ALCAEGMVRSTAVLRGVDWLLRAQEPDGSWFGRWGANHVYGTGAVVPALVAAGMRPDDPV
IVRAVQWLHRQQNRDGGWGEDLRSYRDQYWLGRGASTASQTAWALLALHAAGVGDSAAAW
RGVHWLVQTQRPDGSWDEPHYTGTGFPGDFYINYHLYRLVFPVTALGRLLDAAGTRDAST
DVVAGTRSTEANIGIPSAGGDIVGIPSAGGAVGVLPTGGGAGS
>A0A6P1RFQ6|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. LCT2|TrEMBL
MDSLNATAREAQESKISESKILESKILESSIASATQGVLGFQQSDGHWVFELEADCTIPA
EYVLLRHYLAEPVDTVLEAKIGNYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGD
SIDAPHMVRAREAIHARGGAIHSNVFTRFMLAMFGIVTWRAVPVLPIEIMLLPFWSPFHI
NKISYWARTTMVPLMVIAALKPRAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFLLF
RSLDAILRVIEPLFPKSLRKRAIDTALAFSEERLNGEDGMGAIYPPMANLVMMYDALGKD
ENYPPRAVTRRGIDKLLVIGDDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLD
WLIPKQELEVKGDWAVKRPDVRPGGWAFQYNNAYYPDLDDTAVVVMSMDRMRREHGATSY
DSAIDRGREWIEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCVSML
AQLGETAKTSKHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVRHDDPM
IRKAADWLASIQNKDGGWGEDAVSYRLDYKGWEAAPSTASQTAWALLALMAVGEVDHPAV
ARGVEYLIATQNEKGLWDEQRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRNTNSRV
VGVGM
>A0A846BTP4|squalene-hopene cyclase|EC 5.4.99.17|Symploca sp. SIO1B1|TrEMBL
MQTQDSITTESTESIAEAMAKAQNYLLNLQYPEGYWWAELESNVTITSEVVLLHKIWGTD
QARPLHKVEAYLRSQQREHGGWELYYGDGGDLSTSVEAYMALRLLGVPATDPALLKAKKL
ILERGGISKTRIFTKFHLALIGCYDWRGVPSIPPWVMLLPEQFLFSIYEMSSWARGSTVP
LLIVFDHKPVYQTNPGITLDELYTEGASNVRFELPRNGDWTDLFVTLDDTFKLAEDLDFV
PFRQEGLEAAERWVLERQEVTGDWGGIIPAMLNSLLALRSLNYDVTDSVVVRGLEAVDNF
AIETAETYTIQPCISPVWDTAWVIRALVDSGIAPDHPAVVQAGEWLLSKQILGYGDWAVK
NPQGKPGGWAFEFENRFYPDLDDSAVVVMALDAVQLPQEDHKRTAIARAVAWMASMQCQE
GGWAAFDINNDADWLNYLPYADLKAMIDPNTADVTARVLEMLGSCNLSIEQSKLERSLTY
LLEEQEADGSWFGRWGVNYIYGTSGALSALSVITPEKHRLSIEKGANWLVGCQNTDGGWG
ETCRSYDDPKLKGQGDSTASQTAWALIGLMAAGEATGNGATEAINRGINYLVTTQLPDGS
WNEDYFTGTGFPSHFYLKYHFYQQYFPLIALGRYLK
>A0A6M5Z1H6|squalene-hopene cyclase|EC 5.4.99.17|Frigoriglobus tundricola|TrEMBL
MSHTPSRPAAEPVSERDAAWFEELTGAVARGRTGLLARQRPDGHWVGELEGDTILESEFI
LLLAFLGKLDDPRITPAANYLRKHQQPGGGWSNYTDGPAEISVSVKAYFALKIAGDSADE
PHMKRAAAVVRALGGAEASNSFTRFYLALLGQVPYSACPSVPAEIILLPRWFYFNVYALS
AWSRTIFVPLSVVDAYKPVTQLPERLCVRELFLAPPEAPRWPAKPTKEWFSWTNFFLGVD
YCFKALEHWGLTPLRRRAVRTAVNWMRERYADSDGVGAIFPPMVYNAIVLKCLGVPDSDP
EMRWALKQIDDLCIYEGDTLRLQPCLSPVWDTALSLIGAADAGLPGRAPECEGAVRWLLD
KEVRRAGDWSKTVRGVEPGGWFFEYRNGFYPDTDDTSMVLIALARGDHATREACAGPIHR
AVSWLLAMQNRDGGWAAFDRDIDKQILERVPFADHNAMLDPSCPDITARVLEALSHYGFR
VGQAPVDAAVRFVLARQEESGAWFGRWGVNYIYGTWQVLVGLQAIGFDMTRPVVRRAVRW
LKDVQNEDGGWGESCTSYDDPTTAGRGTSTASQTAWALLGLLAAGEGAGPEVRAGAEFLV
GTQHADGGWTEGPFTGTGFPRVFYLKYHMYPVYFPLMALARYASAVGRRPAGDTTRADAG
HSVVGPKGIARSTLADR
>A0A8A7JMF1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces rimosus subsp. rimosus|TrEMBL
MTTTADDAPREKGPLPAAEEEAARRAVRRAADHLLSRRHTGGWWEEEFTTDVSYDAHDLF
LRHVLGILDERVATAGGRWIRSQQSADGSWPLVFGGAGHLGTTVQAYVALRLAGHRPDED
HMGRCAAWVREQGGVAAAPLEAHVWLAMCGLWCWDDLPEIPPEIIALPTWAPLNIYAFSS
IMRQALVSLGVISAYRPVQPVPFGIDELFVPSDGTPVRPVSAPITRWAGVFQRANTVLRA
GRRITPRAVRRIATNMCARWLLERQETDGSWGACTPITTWVTLALHLHGYAPDHPVLKAA
LRFLDESASWPEDDMRKLRTVRSPVWDTGLAVTALLDAGLDAGHPALVGAADWLLARQSD
RPGDWTARRPRLAPGGWAFQFHNRTYPDNDDTSEVVLALLRIEHPDRARVDDAVRDAVRW
CLGMQSADGGWAAFDVDNASALPGKLPFFDFGEYCVDAPTADITAHVVEMLAAAGMADDP
RTRRAVQWLLGRQEDDGAWFGRWGVNHVYGTGCVLPALIAAGTPCGHPAVRRAVTWLTSV
QNDDGGWGEDWESYADPGRVGRGPSVPSQTAWALLALLAAGERDSAAVRSGVRWLTGRQT
DDGTWEEPEFTGVLVPRAVACRYGYYRHVFPLMALGRYVHRRDAAATR
>Q0RMV6|squalene-hopene cyclase|EC 5.4.99.17|Frankia alni (strain ACN14a)|TrEMBL
MPDLELRDVDRADGRHHAPNLGRTDTLSPSAPTGEPAPASTPAAVATPTPTPTTAPAPAP
APENALRETVQRAAEHLLRLQDPRGWWKFDLETNPTMDAEDLLLREYLGIRTVEQTEATA
KHIRSRRLDDGSWPTYFGGPGELSTTVECYIALRLAGDSPDDEPLRRSAAWIRERGGIPA
TRVFTRIWLALFGWWRWEDLPVLPPEIMFLPPRAPLSIYSFASWARQTIVPLTIVSAARP
QCPAPFDLAELDPDEVPAAQSHGAAQSPDTRSPAGGRTLRGAMRRLGGDRPNTAKVFFRG
LDAALHRYHRHPIGPLRRHALRTAERWIIARQEADGCFGGIQPPAVYSIIALRLLGYDLD
HPVLAAALRSLDAYTLHREDGSRMIEASQSPIWDTALAVLALADAGIDAPADVDVAPALP
TQRVATGAPAPSAPVPTALERAADWLLGQEIQHRRGDWAITHPGVAPGGWAFEFDNDTYP
DTDDTAEVVLALHRLNRLRRLRHPTNTRIDAALERSTAWLFALQSRDGGWGAYDSDNAST
LVYQIPFADFGALTDPSSADVTAHVVELLCETGRIRDPRTLRGVDWLLRNQEADGSWYGR
WGVNYVYGTGSVLPALQAAGLPPTHPAMVAGARWLLSRQNSDGGWGEDIRSYGDPAWSGR
GLSTPSQTAWAMLGLLATDHGGVHADALAAAARWLTEQQRPDGGWDEEMFTGTGFPGFFY
LNYHGYRLVWPVMALGRYLHSRQHPSD
>S0EWC1|squalene-hopene cyclase|EC 5.4.99.17|Chthonomonas calidirosea (strain DSM 23976 / ICMP 18418 / T49)|TrEMBL
MRHLLYKMSVYVVFLAISLIGARTAAAAPDALIAQAQKAVQKGINYLHRVQEKDGSWSHY
PGTTALALAALLRNGHNELNDPAVAHGIQYLLHLVKPNGGIYDDRDPNLALPNYNTSLSM
MALYLTHNPAYKPIIAKAQKFLEDSQFGATDGMKPSNPFYGGIGYGSDPDDHPDLSNLAT
ALEALKDTGVPANAPVWKRAIIFLQRVQNRKESNDQAWAKTGPNDGGFVYDPLGGSKSPQ
GYRTSYGSMTYEGLKSYIYCNVSRKDPRAQAAWNWIRSHYSVTTNPGMGTAALYYYYHTM
AKTLAVYGQKYVIDTHGKPHDWQKDLIQQLIRLQHPDGSWFNTNARFWENQPALVTSYTL
IALAYCLHPNS
>A5GB12|squalene-hopene cyclase|EC 5.4.99.17|Geotalea uraniireducens (strain Rf4)|TrEMBL
MNSCKHPISHALTSFNGETADAAKKQPVKPGAKIHHLPASIWKKKEGESKSPLDIAIENS
RDFFFREQLPDGYWWAELESNCTITAEYLMLYHFMGIVDQERERKMATYLLSKQTAEGFW
TIYFGGPGDLSTTVEAYFALKLAGYPADHPAMAKARAFILDNGGIIKCRVFTKIFLALFG
EFAWFGVPSMPIELILLPNWAYFNMYELSSWSRATIIPLSIVMTERPVRKLPPSSRVQEL
YVRPPRPIDYTFSKEDGIITWKNFFIGVDHILKVYESNPIRPFKKRALATAENWVLDHQE
STGDWGGIQPAMLNSVLALHCLGYANDHPAVAKGLEALANFCIETEDSLVLQSCISPIWD
TALALKALVDSDVPTDHPALVKAAQWLLDKEVRKPGDWKIKCPELESGGWAFEFLNDWYP
DVDDSGFVMMALKDVAVKDRKSMDGAIKRGINWCLGMQSKNGGWGAFDKDNTKYLLNKIP
FADLEALIDPPTADLTGRMLELMGTFGYSKDYPAAVRALEFIKKNQEPEGSWWGRWGVNY
IYGTWSVLGGLAAIGEDLNQPYIRKAVNWLKSRQNMDGGWGETCESYHDTSLAGIGESTP
SQTGWALLSLMSAGEANSSTVARGIQYLIANQKSDGTWDEEQYTGTGFPKFFMIKYHIYR
NCFPLTALGTYRKLTGGMA
>A0A5C8VYA6|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium sp. WL119|TrEMBL
MREAVNKVEALQRPKTQAISLDDVDHGVARATRALTALAQADGHICFELEADATIPSEYI
LFHQFRDTRPPEGLEPKIGNYLRRTQEKHGGWALVHEGPFDMSCTVKAYFALKMIGDDIE
APHMRRAREAILSRGGAAQSNVFTRFILALYGEVPWSAVPVMPVEVMFLPKWFPFHLDKV
SYWARCVMVPLFVLQATKPRAKNPRGVGIGELFLTPPSSVRRWPGSPHATWPWTPIFGAI
DRVLQKVEAYFPHRIRLRAMEKARAWVSERLNGEDGLGAIFPAMVNTVLMYEAMGYGPDH
PQVRVACDAIEKLVVVKAHEAYVQPCVSPVWDTALAGHALLEAGGTDAEGQARAGLDWLL
PRQVLDIAGDWAAAKPKVRPGGWAFQYANAHYPDLDDTAVVVMAMDRAMRQHGLVANMPD
YTASIARAREWVEGLQSKDGGWAAFDADNNHMYLNHIPFSDHGALLDPPTADVTARVVSM
LSQLGETRESSKALDRGVTYLLNDQEQDGSWYGRWGMNFIYGTWSVLCALNAAGVDPASP
EIRRAVEWLIRIQNPDGGWGEDASSYKIDPAFEAGSSTASQTAWALLALMAAGECDDPAV
TRGINFLARTQGTDGFWNEERYTATGFPRVFYLRYHGYPKFFPLWAMARYRNLKRGNSRR
VAFGM
>A0A7V7WNP8|squalene-hopene cyclase|EC 5.4.99.17|bacterium|TrEMBL
MSTSQKVLHRPFGPAAEPLIPESLDSSIQRAQQLLLRHQFPEGFWWYTLEANETIGAEYL
FLREFLGIPDPKLSRALCQRMLSQQRADGSWAIYYNGPGDLSTTVECYWALKMSGYSVDD
PAMLRARGFIRSHGGPTKVRVFTKIHLAMFGLAPWSAAPAMPYIFMMLPRWAPINIYEFS
SWARACIVPLLIVLNERPVHKLAIDLEELYPEAPADRDWSISSTEGDWFSIGKVFLSVDK
FLKNIEKIKVPRFKRGSAVKRCLRYIREHIEKTEDIYPAMAYSALALKTLGYPNEDPTMR
QCLKGLAAFHQLCDGDLLHIPKQAGADLDGDRRYLHQQCCISPVWDTPWAAVSLCDSGLN
PEHPALRRAAEWLVSKQITDVKGDWAVKKPRLKPGGWSFEFKNDYFPDVDDTLEVLSLFH
KIGYPSAEIKRSFDLGLDWLLGMQSKNGGWAAFDVDNDLHLVNKIPFSDHGACLDPPTPD
ITGRMLEFLALIGWDRDSSVVQRALKFVYREQLESGAWEGRWGVNYVYGTWCVLQGLAAI
GEDLSDPRIQKAVTWLKRVQLHDGGWGESCAGYAEDRFVSLPYSVPSQTAWALMGLIAAG
EADSPIVERGIEFLIRRQNDHGCWDEREYTGTGFPGHFYIRYHGYRHYFPLLALGRYRRA
KPQ
>A0A4P7Z2L0|squalene-hopene cyclase|EC 5.4.99.17|Azospirillum sp. TSA2s|TrEMBL
MDGPTSFSDTDHDLDRLIDHSAIALEALQREDGHWLFELEADVTIPAEYILMRHFLGDPA
DSKLEARLGSYIRDVQGRDGGWPLFHDGDADISASVKAYFALKMIGDDPQEPHMRRARAT
ILAAGGAARANVFTRILLALYGEVPWHAVPAMPVELMLVPRWFPIHLTKMAYWSRVVIAP
LLILLALKPRARNPRDVHIRELFTIPPEQERRYNINPTGSLSGKAFLMLDHVLRAVDPWV
PRRLRRHAIRNAETFILARLNGEDGLGAIFPAMVNAVLALDVLGRPRDHPQVLTVRRALD
RLLTVRDQGTYCQPCVSPVWDTALSVHALVEAGAAADGPVLRPALDWLRDRQILDRAGDW
VNGRGDRTPRPGGWAFQYENPLYPDLDDTAMVAMALHRSDPERYADAIARAKEWIIGMQS
RDGGWGAYDADNTNHYLNHIPFADHGALLDPPTADVTARCLTFLAQTGLGRDQPALASAI
NFLLRHQEPDGSWFGRWGANYIYGTWSVLSALAAVGEDPGSPAIRRAVAFLASRQRPDGG
WGEDCATYWHARKNEVKASTPSQTAWALLGLMAAGEEKGLVVQRGIAFLGQAPRNGAHWL
EKHHTGVGFPRVFYLRYHGYSAYFPLWALARYRAQHRRNRMTIAETLMASNP
>A0A3A4REM0|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Aureabacteria bacterium SURF_26|TrEMBL
MKQDQKVSLLTSFINPSVFTQIKDRIGSKKKLYEDQIKASLNKLESISLESGREHLLDPQ
CVLSLAIKKSQDYHFSVQHPDGHWVAELEANVTLTAEVIFLMHFMDMVDDEKVQKCARYI
LSRQSPDGSWPIFYGGDGDISASVEAYFALKLAGYSPDKKCMRAAREYILRNGGVQKVRV
ITKIMLGFFNQYTWEGIPSLPVEMIFIPRVCSFNLYEFSSWARICVVPLTVLMHYKPIVA
VPDGLGIEELFSDSPDAQEHRFDKNSGLLSWNNFFIGVDKVLKLLEKSPISISKKRALKK
AEKWILDHQDSSGDWGGIFPAMAFSIMALRTLGYLNDFPPIKKGFEAIERFQIKDESMIH
QQSCVSPVWDTAWASFALYESGISGSDPLLQKAAHWLYNKQTTQFGDWKVKNQNAEPGGW
SFEYYNEFYPDTDDTGVVIMALLNIHGVKGIRKNDRITKGLSWLMNLQNSDGGWGAFDKD
VNNPIYNQILFNDLKTMLDPSCPDITGRTLELLGKLGYTSEFLPVALAVEYLKREQHPDG
PWYGRWGVNYIYGTWAALTGLQAIGEDVNQAYIQRGIQWLFSIQNSDGGWGESCLSYHSS
EYIGKGTSTPSQTSWALIALVSCGYADDARVRRGIRFLTDKQLDNGSWEEPEFTGTGFPR
SFYIRYHMYKDYFPLLALSTYRKAVNSGIAS
>A0A494XC79|squalene-hopene cyclase|EC 5.4.99.17|Trinickia fusca|TrEMBL
MNDFSAASAAVAAASASHDASQRAGLDGAIEQATDALLAAQQADGHWVYELEADATIPAE
YILLVHYLGETPNVELERKIVRYLRRIQLEDGGWPLFTDGALDVSASVKAYFALKMAGEP
ESAEHMQRARRAILGAGGAEAVNVFTRILLALFGVMSWRAVPMMPVEITLLPKWFPFHLS
KVSYWARTVIVPLLVLNARRPVARNPLGVHIDELFHGKPSEAGMLPRAPHQSRGWFAFFR
VVDKVLRATDGLFPKGSRQRAIDAAVAFVDERLNGEDGLGAIFPAMANSVMMYDTLGYAP
DHPNRAIARRSIEKLLVIGEDEAYCQPCLSPVWDTSLAAHALLETELPRAEQAALRGLQW
LRPLQILDVRGDWISRRGDVRPGGWAFQYANPHYPDVDDTAVVALAMDRAATLTRSNVDR
EAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLA
QLGELPGNSEPARRAYEYLLDEQEDDGSWYGRWGMNYVYGTWTALCALNAAGIAHDDARV
KRAAQWLISIQNEDGGWGEDGTSYKLEYRGYERATSTASQTAWALLGLMAVGEVNHPAVA
RGVEYLMRTQCEHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNMTRAKRVRV
AVGL
>A0A7W8DZD5|squalene-hopene cyclase|EC 5.4.99.17|Rhodopseudomonas rhenobacensis|TrEMBL
MQSGINEQPMIGREALDASIDAATRALLGFRQDDGHWVFELEADCTIPSEYLLLRHYLGE
PGDVALEAKIGNYLRRLQGAHGGWALVHDGAFDISASVKAYFALKMIGDDVDAPHMAKAR
EAIRSRGGAIHSNVFTRFMLSMFGITTWRSVPVLPVEIMLLPMWSPFHLNKISYWARVTI
VPLMVLAALKPRAVNRLQVGLDELFLQDPKSIGMPAKAPHQSWALFKLFAGIDTVLRTIE
PWFPKRLRAYAIGLAVKFIEERLNGEDGLGAIYPPMANTVMMYKVLGYPEDYPPRAITRR
GIDKLLVIGDDEAYCQPCVSPIWDTALSCHALLEVGGEAAVPPAKRGIDWLAPKQVLDLK
GDWAVKRPELRPGGWAFQYNNAHYPDLDDTAVVVMAMDRSRRATGSAEYDEAIARAREWI
EGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGAMLDPPTEDVTARCVSMLSQLGETAASSK
PLADGLAYLRRTQLPEGSWYGRWGMNYIYGTWSVLCALNAAGLDHQDPAIRKAVAWLESV
QNADGGWGEDAESYRLDYKGYQQAPSTASQTSWALLALMAAGEVESAAVARGVEYLKSTQ
SGKGYWDEQRYTATGFPRVFYLRYHGYAKFFPLWALARYRNLRSTNSKAVGVGM
>A0A537QMK7|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MNDGMTTRGSVTPIRERGAAGLDEAVTRACTSLLALQRADGHWVFELEADVTIPSEFILL
QHYLGRIEPEVEVRIARYIRATQGADGGWPLFHSGALDISASVKAYLALKAAGDPVDAPH
MVRARSAILARGGARRCNVFTRATLALFGEVPWRAVPVMPVEIMLLPLWSPFHLSKVSYW
SRTVLVPLLVLMALRPRARNPKRVTIRELFCEPPESVRDWITGPTSSPLSLAFGILDGLL
RKTEPFFPPGARRRAIERAVAFVTERLNGEDGLGGIFPAMANAVMMFDCLGYRPDHPDYA
IGWAALRKLLVLDGERAYCQPCLSPVWDTALTCHALMEVDDARLAPTIGRALDWLEAKQV
LEQVGDWGATRPEVRPGGWAFQYENPYYPDLDDTAAVALALDRFDRTRYRRAIDRAAEWV
VGMQSRNGGWGSFDADNTHYYLNHIPFADHGALLDPSTADVTARCLGFLAQIGFAADHPT
LSAAMEFLRKEQEPEGSWFGRWGTNFIYGTWSVLAAFNAAGIAPASAEMRRAVDWLVARQ
HGDGGWGESGESYWPDAQHGDAPYSTPSQTAWALLGLMAAGRFEHPAVVRGIDYLVNSQD
QDGNWDEPWYTAVGFPRVFYLRYHGYRTFFPLWALARYRRLRTESCRRVSFGI
>A0A6G2WNF7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8375|TrEMBL
MTATTDGSTGALPPRAPSASDATAENTAPPAATRTAVRQDTVDAARRATARATDYLLSVQ
DPAGWWKGDLETNVTMDAEDLLLRQFLGIQDPELTEAAARHIRGEQCADGTWATFYGGPG
ELSATIEAYVALRLAGNAPDAPHMAKAAAWVRGQGGIAAARVFTRIWLALFGWWKWDDLP
ELPPELLYFPKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRLAPFALDELHTDPRRPNPP
RPLAPVTSWDGVFQRLDRALHLYHKVAFRKLRAAAMRSAARWIIERQENDGCWGGIQPPA
VYSIIALHLCGYDLDHPVLRTGLASLDRFAVWREDGPPGPDGPGGAPTRMIEACQSPVWD
TCLATIALADAGLPADHPQLVKAAEWMLAEQIDRPGDWSVKRPQLPSGGWGFEFENDNYP
DIDDTAEVVLALRRVRHPDPLRVEAAVRRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLP
FCDFGEVIDPPSADVTAHVVEMLADVGRTHDPRTRRGIAWLLAEQEAGGAWFGRWGTNYL
YGTGSVLPALAAAGVPASHPAVRRAVRWLERVQNDDGGWGEDQRSYQDKEKWAGRGASTA
SQTAWALMALLAAGERGSEAVRRGVHWLTATQREDGSWDEPYFTGTGFPWDFSINYHLYR
QVFPLTALGRYLNGGPAGAPVGA
>A0A7W7YFX9|squalene-hopene cyclase|EC 5.4.99.17|Prosthecobacter vanneervenii|TrEMBL
MMDALDRAIGSTQAHLDALRTADGHWEGRLSSSALSTATALVALTLVDRHAHAAPIAAGA
RWLCTHQNAQGGWGDTTLSKSNLSTTLLCWSALHLWSAGSEEQSRAAAPSIQQASGWIIT
QTGSLAPEVIARAVISRYGKDKTFSVPILMLCCLCGTLGERPWRHVLPLPFELAALPRTW
FGAIGLPVVSYALPALIAIGYTRFKNNPPAWWNPLRWVRALAWPRIRPMLKDLQPSSGGY
LEATPLTSFVTMALAGGGQLDHPCIPQAVDFLIRSKREDGSWPIDTNLATWGTTLSLRSL
EQPDVQPELRTWLQAQQYRVVHPFTNAPPGGWAWTDLPGGVPDADDTSSALIALKKIGHP
CDAAIQQGITWLLNLQNRDGGIPTFCRGWGTLPFDRSTPEITAHALGAWWSWHEELPTEM
QLRIGKATQQALAYLKRVQLSDGSWIPLWFGNEHTHDENNPVYGTAQVVNHLSGSTHLST
LFEGLIQSGRKFLLTSQKADGSFGGDTQSPPSIEETAVALRALCSAGAAVRAQVQAASSW
LVAATQNGTVFPPSPIGLYFARLWYHEQLYPVVWTLEALQAAKEVLDQ
>A0A5A9X7J9|squalene-hopene cyclase|EC 5.4.99.17|Oryzomonas rubra|TrEMBL
MHSKTKTKLNVIEGGRGAKQAEAVASANTFLHVESVLEKAAHQLAALQNEDGHWVFELEA
DVTIPSEYIMLQRFLGRSVDEKTASRLSSYLLDRQLPDGSWPLYAVDGNANISASVKAYF
ALKLLGHDKNASYMVKARQIILSLGGAARCNVFTRITLALFGQVPWHTPPAMPIEIMLLP
RWFFFHLSKISYWSRTVIVPLLILYAKQPVCALRYNEGITELFTTPPDMLGNLDHFRHRA
WRKNVFIVLDRVLKRTMHHIPKRIGAHALRQAEQWTRARMQGEGGIGAIYPAMANAVMAL
KTLGCREDDPDYVRGIAALDDLLIHRTPAPDAVPHNSPFGGGIDRSSAAPDLLLSRHAAT
ARDDHFSLCQPCNSPVWDTCLSLSALVEAGIPGNLFSADEAMKWLFDRQISTPGDWSGNC
PGLACGGWAFQYENTLYPDVDDTSKVLMGLFRAGALEREEYREKIAKAVRWVIGMQNSDG
GWGAFDVDNDYLYLNDIPFADHGALLDPSTSDLTGRCIEMLGMLGYGPDFPPIARGLAYL
EKEQEAFGGWFGRWGVNYLYGTWSVLSGLHEVGEDMQKPYVRKAVEWLVGCQNGDGGWGE
TCASYDDPSLAGSGASTPSQTAWALLALMAAGETDRPEVQRGTQYLVDRYHNGWEERHFT
GTGFPRVFYLRYHGYRLFFPVWALGAYLRRRRGATTVQDAVRRKYMGGVSWLKLQ
>A0A522GEC5|squalene-hopene cyclase|EC 5.4.99.17|Beijerinckiaceae bacterium|TrEMBL
MNECATLIAASVPKGSPTLDEVERGIAETTRTLLDEQKPDGHFVFELEADVTIPAEYVLY
HHYLGEPAPAELEAKIGRYIRRLQSAVHDGWPLLHSETFDISATVKAYFALKAIGDSVEA
PHMRRARAAILAHGGAAESNVFTRALLATFEIVPWRAVPIMPVEIMHLPEWFPFHLSKIS
YWARTVLVPLMVVMSLKARARNPLGIRLDELFVVPPDKVRHWPDGPQKSFPWSGVFGALD
AVLRALEPYIPRRVRQSAVAKAVQFVDERLNGEHGLGAIFPAMINAAEMYDVLGYPEDDP
NYTLARVAIEKLLIVKDDEAYCQPCVSPVWDTALMAHALIEAGGEEADAAVGRALEWLKP
LQILDLRGDWALKRPATPPGGWAFQYVNEHYPDLDDTAVVVMAMDRAGKSLQAVGPDEYT
RAIADARRWVEGMQSHNGGFGAFDADNDHTYLNYIPFADHGALLDPPTADVTARCVSMFA
QLGETPQNNLQVASAVDYLLREQEKDGSWYGRWGINYIYGTWSVLCALNAAGLDHKCEAF
QRAVTWLKAIQNEDGGWGERGDSYAFDYAGYKKAPSTASQTAWALLALMAAGEVNDPAVA
RGIRYLLDSRGETGSWHEENFTGTGFPRVFYLRYHGYSKFFPLWAMARFRNLSRANHPGV
HVGM
>A0A7Y6L9Q0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. CAI-85|TrEMBL
MTATTDGSTGAALPPRAAAATDTDITIPVAAGGQEAAVRAVQRATAHLLARQDAEGWWKG
DLETNVTMDAEDLLLRQFLGIRDDATTQATALFVRGRQREDGTWATFHGGPPDLSATVEA
YVALRLAGDAPEAPHMALAAAWIRDRGGIAAARVFTRIWLALFGWWKWEDLPELPPELLY
FPKWFPLSIYNFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPDLPNPPRPLAPLHT
WDGLFQRLDKVVRGYRTVAVRRLRGAALNSAARWIVERQENDGAWGGIQPPAVYSIIALH
LLGYDLAHPVMRAGLESLDRYAVWREDGSRMIEACQSPVWDTCLATIALADAGVPADHPQ
LVKAADWMLGEQIVRPGDWSVRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVAHHD
PQRTEKAIARGVRWNLGMQSRNGGWGAFDVDNTSRFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGLSHDPRTRRGIAWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALTAAGLPARH
PAIRRAVGWLERVQNDDGGWGEDLRSYQDPARWSARGASTASQTAWALMALLAAGEKDSK
AVERGVAWLVETQREDGSWDEPCFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFAD
RPATGAAPAEAEGG
>A0A4E0QGQ1|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium yuanmingense|TrEMBL
MDSVTATSREALESSIASATQGILGFQQSDGHWVFELEADCTIPAEYVLLRHYLAEPVDT
VLEAKIGNYLRRIQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDSIDAPHMVRAREAIH
ARGGAINSNVFTRFLLATFGVVTWRAVPVLPIEIVLLPFWSPFHLNKISYWARTTMVPLM
VIAALKPRARNPKGIGIDELFLQDPRSIGMTAKAPHQSMAWFLLFRSLDAILRVIEPLFP
KSLRKRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKDENFPPRAITRRGIDK
LLVIKDDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLDWLIPRQELEVKGDWA
VKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGAAGYDDAIARGREWIEGMQ
SDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETAKTSKQVAA
GVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDHKDPMIRKAAAWLTSIQNDD
GGWGEDAVSYRLDYRGWEAAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIATQDKKG
LWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A7C2UEX8|squalene-hopene cyclase|EC 5.4.99.17|Acidobacteria bacterium|TrEMBL
MGEGAELGLGTAAAPRRAVAYSEPRVEERLEERLKHAVERGVEYLLSIQHSEGYWLGELE
ADTTLESDYVLYLHVLGKLERSRVAKLANQIRKKQLPDGGWSTYEGGPSELNSTVKAYLA
LKIAGDSPDFPHMERACQRVHELGGLEHSNSFTRFYLALVGAVGWEMVPAVPPELMLSPD
WFYLNIYEMSSWTRAIVIPLMILYARKPLWQLPAHAHVDELFRNPAAKKIAFHWDEQFLT
WRNFFLALDRLFKLYEKLPWKPFRERALGRARQWLLEHLERSDGLGAIYPAMMNSVFALL
ALGHAVEDPLTAREVRHLEKFEIEEEDTMRLQPCLSPVWDTAIAMAALEEAGLPPNHPSL
IKAARWMLDQQILGPGDWQVKNPNTKPGGWAFEFRNDFYPDVDDTAFVLMALQRVDFPDR
ARMEEAVRRGITWMLSMQNRDGGWGAFDRDNDCAILTQVPFADHNAMIDPSTEDVTARVI
ECLGRFGWNATHPVVKRALAYLMREQKDDGSWYGRWGVNYIYGTGGVLRALEPLSLTGRE
EAQRGAAWLESVQNHDGGFGETCASYNDENMKAKGPSTPSQTAWGLIGLLAVVEPNHPAI
VRAVNWLLDTQGEDGNWSETATTGTGFPCVFYLKYHLYRNTFPLYALARLQNIRKSAETF
CGLLLSPHQFERRNGSRANR
>A0A4S2RLV3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. A1547|TrEMBL
MTATTDGAGTPGADPGSTTPDTVQGAQEAAARATRHLLARQDAAGWWKGDLETNVTMDAE
DLLLRQFLGIRDEATTQAAALFIRGEQREDGTWATFHGGPPELSATIEAYVALRLAGDAP
DAPHMARASAWVRAHGGIAAARVFTRIWLALFGWWSWDHLPELPPELVFLPPWVPLNIYD
FGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDARRPYSPVNRPAPLVSWEGLFQRMDK
ALHVYRRFAPRRLRKAAMDTAARWIIERQESDGCWGGIQPPAVYSVIALHLLGYDLAHPV
MRAGLESLDRFAVWREDGARMVEACQSPVWDTCLAAIALADAGLAPDHPALVKAADWMLG
EEIVRTGDWAVRRPGLAPGGWAFEFHNDTYPDIDDTAEVVLALRRIRHPEPARVEAAIAR
GVSWNLGMQSGNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTAHVVEMLAVEGKA
ADPRTRRGIAWLLAEQEPGGAWFGRWGTNYVYGTGSVVPALTAAGFAPGHPAIRRAVRWL
ESVQNEDGGWGEDQRSYKDPEWAGKGASTASQTAWALMALLSAGERHGKAVERGIGYLVE
TQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLYGEPFAPGEA
>A0A506US07|squalene-hopene cyclase|EC 5.4.99.17|Oecophyllibacter saccharovorans|TrEMBL
MPLAGGVLSGQRAASLSADEQGGLVETKLDPETVDQAITGAHAALGKRQNEDGHWVFELE
ADATIPAEYVLLEHFLDRIDEERQKKIGVYLRRIQGAHGGWPLYHDGKFDLSASVKAYFA
LKAIGDDPQAPHMKRAREAILAHGGAERTNVFTRIQLALFDQVPWRAVPVMPVELMLLPR
KAFFSVWNMAYWSRTVIAPLLLLGDLKPVARNPRGVDVQELFRTPPGKIRDWIRGPYRSQ
WGRVFKYLDTALRPVVPLFPQKLHRKAVDTTLAFIRKRLSNGGLGAIYPAMANVVMMFRA
LGVPDEDPHAVQAWQAIQDLMIEKDGEVYCQPCVSPIWDTGLAGLAMLETASGPRATQPR
ETRERLEKSAAWLRERQILDVKGDWAVNAPDLRPGGWAFQYENDYYPDVDDTAVVGMLLH
RLDPETNATAIARAREWIIGMQSTNGGWGAFDIDNDLDVLNHIPFADHGALLDPPTADVS
ARCISFLAQLGHPEDRPVIDRALDYLRQEQEESGSWFGRWGTNYIYGTWSVLCALNIAGV
DPRDPMVVKAVQWLKSVQREDGGWGEDCASYEGAPQGVYKESLPTQTAWAVLALMAAGER
ESEAVKRGIAALTRMQDGHGEWHEEPYNAVGFPKVFYLRYHGYKQFFPLMALSRYRNLGA
SNSGRVEYGF
>A0A3M2BZY3|squalene-hopene cyclase|EC 5.4.99.17|Acidobacteria bacterium|TrEMBL
MQNTQQALLEDLEPQVDERPSSATSALRRAIAAARRGLVALQREDGHWCAELEGDTILES
EYILTLHFLGLADPQRVAKLANFIRRQQLPAGGWTIAPGCRPDVSSSVKAYLALKLAGDD
PAAEHMVRAREAILRLGGIEACNSFTKIYLSIFGLYDWRRCPAVVPEMILMPRWFYFNIY
AMSSWSRAIVIPLAIIWAKRPLHRLGVDLDDLAGAAPVPEAGGGSFKRRFWSLVFRAING
GLHLLESARLLPLRRRALARCEQWVLDRLEDSDGVGAIFPPIINTLIGFRSLGYPMDHPV
IQSQLHELEKLEVDDGDEMRVQPCFSPVWDTAIALDALGESGMERNDAVVQRAGRWLLER
EIKRPGDVQILYPEVPSEGCWFFEYRNAFYPDCDDTAEVLKALSRVRFDAPETEGERRAA
IERGLSWLRAMQNDDGGWAAFDKNCNREILTYVPFADHNAMIDPSTSDITARVLEVMLHL
GVDRRAPEIQRALAFLRREQEADGSWYGRWGCNYLYGTWLALQALAAAGEDEDRERIARA
AAWLRRVQNDDGGWGELPLSYDDPTLKGQGPSTASQTAWALMGLAAAGEADSEAVERGIA
YLLAQQREDGTWQDEHWTGTGFPKVFYLRYHLYATYFPLGALSVIERRMARAGSARALRE
WAVA
>A0A0C4YJL4|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus basilensis|TrEMBL
MNARSNAQLNTELNTQSNSQLNTRLNAQPCTRQDAGAPTQATPGTPGADANLHRAIDAAR
DALLSHQHRDGHWCFELESDATITAEYILMMHFVDEIDAGLQAAMAVYLRSLQRQDRHGG
WDLYHGGALDVSCSVKAYFALKAAGDDPDAPHMAQARRAILAQGGAAKANVFTRILLATF
GQVPWRATPFVPVELILFPRWAPVHLDKMAYWARSTLVPLTVLCSLRAKAANPHRVGVSE
LFVTPPERERHYFSSKGLMRKAFLVADKVARTIEPWIPAAVRRRAIARAQAWCVERMNGE
DGLGGIFPPMVYWYEMMTLLGVPKTDPARVTCLAAIRKLVVRRADGSAYCQPCLSPVWDT
AWSIMALQHAGTDARTQQAVQRAYDWLEARQVRDLRGDWSKHVPASVQPGGWAFQYANAY
YPDIDDSAVVAAMLAVHARRIGQPERYQDAVASAVKWMVGLQSRNGGFGAFDANCDREYL
NRIPFADHGALLDPPTEDVSGRVLLCIGLSGNRQAHAAAVERCVAYLRRTQRADGAWWGR
WGSNYIYGTWSVLAGLALVGEDVRQPYIRKAVDWLLHCQHADGGWGETNDSYFDGSLAGT
NGGESTPNSTAWALLALFAVGEVDTPAVRRGIAYLLDCQAGSGLWQHPSHNAPGFPRIYY
LKYHGYTAYFPLWALTRYRQLAGRTVAK
>A0A643FPT2|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus basilensis|TrEMBL
MSQVALSPNSNAPAHAAPAPDELEGTLDRALDALLASQRPDGHWVFELEADATIPAEYVL
LVHYLGETPDTVLEARIARYLRRIQNADGGWPLFHQGRSDISASVKAYFALKMIGDDTES
EPMRRARAAIHGMGGAEASNVFTRTLLALYGVMPWQAVPMMPVEIMLLPLWFPFHLSKVA
YWARTVIVPLLVLNSLRPQARNPRGVGIDELFIRPCQAARLAPRAPHQKRVWFGLFRVLD
AGLRVAEPLFPRSLRARAIARAEKFVRERLNGEDGLGAIFPAMANAVMMFDVLGVPRTDP
DVAVARASIEKLLVVHGDEAYCQPCLSPVWDTSLASHALLEVGGPRAEAAVERGLQWLRP
LQVLDVRGDWIVRRPDVRPGGWAFQYANPHYPDVDDTAVVAMAMDRAARTGAAAPAVAPA
SHRSRYDEAVSRAREWVAGMQSGNGGWGAFEPENTHEYLNNIPFADHGALLDPPTADVSA
RCLSMLAQLGETAASSQAFRRAQRYLLDEQMADGSWYGRWGTNYVYGTWSALCALNAAGM
APEAPEMRRAADWLISIQNADGGWGEDGSSYRLDYQGYETAPSVPSQTAWAMLGLMAAGQ
VDHPAVARGVDYLMRMQQADGLWSEARFTAVGFPRVFYLRYHGYARFFPLWALARYRNLR
RDGTRVVAWGM
>A0A3N4FV65|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia mallei|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANAMRVTVGM
>A0A4Y9LK13|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium frederickii|TrEMBL
MDSVNATSREALQQEALQPGTLQPGILESSIASATQGVLDLQQADGHWVFELEADCTIPA
EYVLLRHYLAEPVDAVLEAKIANYLRRIQGAHGGWPLVHDGEFDMSASVKAYFALKMIGD
SVDAPHMVRAREAIHARGGAIHSNVFTRFLLAMYGVVTWRAVPVLPIEIVLLPFWSPFHL
NKISYWARTTMVPLMVLAALKPRAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFLLF
RSLDAILRVIEPLFPKSLRKRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKD
ENYPPRAVTRRGIDKLLVIGEEEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLD
WLIPRQELELKGDWAVKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGATGY
DTAIARGREWIEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISML
AQLGETAKTSKHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDHKDPM
IRRAAAWLASIQNKDGGWGEDAVSYRLDYKGWEAAPSTASQTAWALLALMAAGEVDHPAV
ARGVEYLIATQNKKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRV
VGVGM
>E1TG96|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. (strain CCGE1003)|TrEMBL
MNDLSQAHVLAAAGPENAGETGSAPATASTATATAPASATATATAASAGFAPALDAAIAR
ATDAILAAQNADGHWVYELEADATIPAEYVLLVHYLGETPNLELEQKIARYLRRIQLPDG
GWPLFTDGALDVSASVKAYFALKMIGDSADAEHMVRAREAILAHGGAEAVNVFTRILLAL
FGVVSWRAVPMMPVEITLLPMWFPFHLSKVSYWARTVIVPLLVLNAKRPLARNPRRVRID
ELFRGAPVNTGMPARAPHQHVGWFRFFRVVDTVLRAVDGLFPKATRERAVRQAVAFVDER
LNGEDGLGAIFPAMANSVMMYDVLGYPADHPNRAIARRSIEKLLVIKDDEAYCQPCLSPV
WDTSLAAHALLETGEPRAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYNNA
YYPDVDDTAVVAMAMHRSGALTQSDVDRAAIARAREWVVGMQSSDGGWGAFEPENTQYYL
NNIPFSDHGALLDPPTADVSGRCLSMLAQLGELPQNSEPAQRALDYMLKEQEPDGSWYGR
WGLNYIYGTWTALCSLNAAGMPHDDPRIRRAAQWLLSIQNEDGGWGEGGESYKLDYHGYE
RAPSTASQTAWALLGLMAAGEVDNEAVARGIGYLQREQREHGLWDETRFTATGFPRVFYL
RYHGYRKFFPLWALARFRHLKRNGLTRVAVGM
>A0A3B1D420|squalene-hopene cyclase|EC 5.4.99.17|hydrothermal vent metagenome|TrEMBL
MKATGWLKNCQNEDGGWGETCLSYAQPELRGQGVSTASQTAWAVLGLVAGGEAESLAAKK
GVEFLLKTQNAEGTWFEAEFTGTGFPEHFFIKYHMYQHFFPLMALSRYRKALQEERDG
>A0A4U8Z138|squalene-hopene cyclase|EC 5.4.99.17|Methylocella tundrae|TrEMBL
MVIDNGNHLLLSGNAEALDFLRRVGGLKGVSQPAEADFAFVDLATKERWRLRPNAGPLPW
WIFAKGRRVPDTGWRDYLGLAKLLIPGRDKRIDEVLTCRGALYDRLWRPFLLAALNTEPA
EGSSKLAGAVVAETLARGGAACRPIVAHGLSAAFIEPAVMHLVKRGADVRLDHRLRKIIF
AGDRAAALDFGDARVDLNVEDEVILATPPGVAQDLMPGLVAPQDFRAIVNAHFKIAPPAG
LPPILGVVNGEVEWIFAFKDRLSVTISGADRLLDAGREELAARLWAEVAEAAHIDQPLPP
WQIIKEKRATFAATPQENARRPRRRDQRRQSDAGRGLDGDRLTRDDRRRHPVRTSRGGCD
RWPQGVTATAFGGQWIKEPGVEGKFGSAVADEGEAPGLALGQIEAAISSAHKALLGQQRP
DGHFVFELEADVSIPAEYILFLHFLGDPAGAELEEKIAVYLRRHQTADDGWPLFAEGAFN
TSSSVKAYFALKMIGDSPDAPHMKRARAAILKHGGAANTNVFTRSLLSLYGATPWRSVPV
MPVELMHLPRWFPFHLSKISYWARTVLAPLVVVHALKPKARNPRNVGIEELFIEPADQVR
RWPGAPHQTFPWTMVFGGIDHVLRWLEPYFPKRSQKRAIDKAVAFVTERLNGEDGLGAIY
PAMAYSAMMFHALGVPASDPRMIQVRKAIDGLLIIRADEAYCQPCVSPVWDTALASHALM
ESAGAGAKTPGEQTGASVREALSWLAPRQVLDVAGDWATQKPHVRPGGWAFQYANPHYPD
LDDTAVVVLAMDRAAKTLPGGGEDASYDEAISRAKEWILGLQSANGGFGAFDADNDREYL
NAIPFADHGALLDPPTADVTARCVSMLAQLGETARTNPALARAVDYLIEEQEEDGSWFGR
WGMNYIYGTLVSS
>A0A8J6UUU5|squalene-hopene cyclase|EC 5.4.99.17|Nodosilinea sp. FACHB-131|TrEMBL
MQTQEPQQLTGLDSATRDAIPEGIAAAQNYLLALQHPDGYWWAELESNVTITAEIILLHK
IWGTDSARPLAKAEHYLRSHQRDHGGWELFYGDGGDLSTSVEAYTALRVLGVPASDPALL
KAKDFILKRGGISKTRIFTKLHLALIGCYDWRGLPSLPAWVMLLESPSPFTIYELSSWAR
GSTVPLLIVFDQKPVYVIEPAVNLDELYAEGIANVRWELPKAGDWSDIFVWLDGAFKFAE
SINFTPFRDEGLRKAEQWILERQEATGDWGGIIPAMLNSMLALRCLGYDVNDPVVRRGLK
AIDNFAVETDDTYWVQACVSPVWDTALGMRSLTDSGLAPDHPSLVQAGEWLLDKQILDYG
DWVVKNPQGKPGGWAFEFENRFYPDVDDTAVVAMALQDVTLPDEALKREAIARAVRWVAT
MQCETGGWAAFDINNDQDWINAVPYGDLKAMIDPSTADITARVLEMHGRLCREPNLASRY
ASDLTAQRLERGLAFLLDEQEADGSWFGRWGVNYLYGTSGALSALALIAPERCQGAIARG
VNWLVSCQNPDGGWGETCRSYDDPALKGQGPSTPSQTAWALLGLIDADSSSAAAKSAIHK
GIRYLIQTQTPEGTWDEQEFTGTGFPRHFYIRYHLYRHHFPLMALGHYHLNYAPNS
>A0A831RK66|squalene-hopene cyclase|EC 5.4.99.17|Chromatiales bacterium|TrEMBL
FGQIPWRGVPFMPVELMLLPRWFPFHLSKVSYWSRTVMVPLLILCTLKRPACNPLGVGVR
ELFTVAPERERHYFPVRSHLNRVVLVFERIGRRLEPLIPRAVRRRAMRAAEDWVVKRLNG
PSGLGAIFPAMVNAYEALAHLGYAPDHPDRAMAMEAIRRLLVVGPDSAYCQPCVSPVWDT
GLACLALQEADGGSGGAEVHRALEWLAARQLRDAPGDWREYRPDLPGGGWAFQFENDYYP
DLDDTAAVAWSMAQARDERFDENVRRAADWLCGMQSRNGGFAAFDADNTRYYLNEIPFAD
HGALLDPPTSDVTARCVTLLSRLLPENPQYRPVVERALGFLRAEQEAAGCWFGRWGTNYL
YGTWSVLVAFQAAGVAAEDPALRRAVRWLDSMQRKDGGWGESNDSYEDSGMAGRGPVGTA
HHTAWAMLALMAAGEGASDAVRRGAAYLLRTQGPDGLWRDEWFNAPGFPRVFYLKYHGYT
AYFPFWALARYRNVSAA
>A0A7W2HSQ8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces griseoaurantiacus|TrEMBL
MTATTDGSTGALPPRAASASESTIGTNSTTGTTPRTTGAKGGVPTASGTRDAATRAMLRA
TDFLLARQDAQGWWKGDLETNVTMDAEDLLLRQFLGIRDERTTRASALFIRGEQREDGTW
ATFHGGPGELSTTIEAYVALRLAGDAPDAPHMAKASAWVRARGGIASARVFTRIWLALFG
WWKWEDLPELPPELIYFPTWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFSLDELHV
DPDRPNPPRPLAPLGTWDGAFQRLDRAMHRVRKVVPRRLRRAAMNSAARWIVERQENDGC
WGGIQPPAVYSVIALYLLGYDLEHPVMRAGLQSLDRFAVWREDGARMIEACQSPVWDTCL
ATIALADAGLPADHPQLVKAADWMLGEQVVRPGDWSVRRPGLPPGGWAFEFHNDNYPDTD
DTAEVVLALRRVAHHDPERMERAIGRGVAWNLGMQSKNGAWGAFDVDNTSRFPNRLPFCD
FGEVIDPPSADVTAHVVEMLAVEGLAHDPRTRRGIEWLLAEQEEDGSWFGRWGVNYVYGT
GSVVPALAAAGLPGSHPALRRAVAWLESVQNEDGGWGEDLRSYHEVAEWSGRGESTASQT
AWALMALLAAGEQDSKAVERGISWLAATQREDGSWDEPQFTGTGFPWDFSINYHLYRQVF
PLTALGRYVHGEPFSKLSGATGGSPAGTEGH
>A0A7W0DRT2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces himalayensis subsp. himalayensis|TrEMBL
MTATTDGSTGAVPPRAASASGTTGTTRTTESTPAAAGTHDAATRALQRATDFLLARQDAQ
GWWKGDLETNVTMDAEDLLLRQFLGIRDEATTKAAALFIRGEQRDDGTWSTFYGGPGELS
TTIEAYVALRLAGDSPDDPHMAKAAEWIREQGGIAASRVFTRIWLALFGWWKWDDLPELP
PELIYFPKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPRNPSPPRPL
APAASWDGVFQRLDKALHAYHMVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYS
LIALHLLGYDIEHPVMRAGFESLDRYAIWRGDGARMIEACQSPVWDTCLATIALADAGLP
ADHPQLVKAADWMLGEQIVRPGDWSVRRPHLTPGGWAFEFHNDNYPDIDDTAEVVLALRR
VKHPDADRVEKAIDRGVHWNVGMQSRNGAWGAFDVDNTSSFPNRLPFCDFGEVIDPPSAD
VTAHVVEMLAVDGKAHHPATRRGIEWLLAEQEANGSWFGRWGVNYVYGTGSVVPALTAAG
LPASHPAIRRAVAWLESVQNDDGGWGEDLRSYRDTEGWSGRGASTASQTAWALLALLAAG
EQESKAVERGIAWLAETQADDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHG
EPFSGKVS
>A0A4P6U1X9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces seoulensis|TrEMBL
MTATTDGSTGAAIPPRAAAASDTDSTDPLAAGVPEATERAVARATEYLLALQDPEGWWKG
DLETNVTMDAEDLLLRQFLGIRDEATTRAAALFIRGEQREDGAWATFYGGPGELSATVEA
YVALRLAGDAPDAPHMARASAWVRERGGIASARVFTRIWLALFGWWKWEDLPELPPELIW
FPTWLPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPANPNPPKPLAPLAS
WDGAFERLDRVVHRLRGAVPRRVRRAAMNAAARWIVERQENDGCWGGIQPPAVYSVIALH
LMGYDLKHPVMRAGLDSLDRFAVWRDDGSRMIEACQSPVWDTCLAVIALADAGVPADHPK
LLKAADWMLAEEIRRPGDWSVKRPELPPGGWAFEFHNDNYPDIDDTAEVALALRRVSHPV
PDRVDGAIARAVRWNFGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMMAAEGLAHDPRTRRGITWLLAEQEADGSWFGRWGVNYVYGTGSVVPALTAAGLPTSH
PAIRRATHWLQQAQNDDGGWGEDLRSYKYAREWSGRGASTASQTAWALMALLAAGERDSE
AVERGVRWLTDTQRDDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFDK
APLATRRGVRATAEGS
>A0A845ILH4|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium japonicum|TrEMBL
MDSVNATSREAQESRARILESGVLESSIASATQGVLGFQQSDGHWVFELEADCTIPAEYI
LLRHYLAEPVDAVLEAKLGNYLRRVQGAHGGWPLVHDGEFDMSASVKSYFALKMIGDSVD
APHMVRAREAIHARGGAINSNVFTRFLLAMFGVMTWRAVPVLPIEIVLLPFWSPFHLNKI
SYWARTTMVPLMVLAALKPLAKNPKGVGIDELFLQDPRSIGMTAKAPHQSRAWFVLFRAL
DGILRVIEPMFPKSLRQRAIDAALAFIEERLNGEDGMGAIYPPMANIVMMYDALGKDENY
PPRAVTRRGIDKLLVFNGDEAYCQPCVSPVWDTTLTAHALLEAGGDTAVPAAKQGLDWLI
PKQELEVKGDWAVKRPDVRPGGWAFQYNNAYYPDLDDTAVVVMSMDRMRREHGATGYDAA
IDRGREWIEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQL
GETETTSKHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVRHDDPMIRK
AADWLASIQNKDGGWGEDAVSYRLDYKGWEAAPSTASQTAWALLALMAAGEVDHPAVARG
VEYLIATQNKKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGV
GM
>A0A6L3V8W3|squalene-hopene cyclase|EC 5.4.99.17|Cytobacillus depressus|TrEMBL
MRHRVHAEMNRIIDQFIRDQSDDGSWQYPFETGIGTDCHMIILLRTLEINDEAFIKELAE
RIAGKQKKDGSWGLFYDEGKGNLTSTVEAYYALLYSGYRDRDDPDIQAARRFILANGGAT
EVHMFFKILLALTGQCEWPPFPIKIEVLLIPDSFPINLFDFSVYGRTNIIPFLILANLGF
SRRTGRSPDLSDLYLKKENRFFTEDPEARSVIHLVKKGINGLKDYPGNLRELALYRAEQY
MLDRIEPDGTLCNYFGSTSMMIFALLARGYSNTHPVITRALQGLKAMTCRIDGELHCQYA
TATVWNTTLISYALQESGVPYSSNTVEKANRYILSRQHVKYGDWIIHEPNLLPGGWGFED
MNTIHPDIDDTTVALRAIRTLAIERVDCRQAWDRGINWLISMQNNDGGWAAFEKNVNKKL
LNLLPIEGGKDLLIDPSTVDLTGRTLEFFGNYTHLDFHHPMVKRGIRWLLKNQESDGSWI
GRWGVYIYGTWAAVTGMVAVGVSPNHPAIQKAVNWLKSIQSQDGGWGESCKSDIENCYVP
LGESTRTHTAWALDTLISATTEVTPDIKRGAAFLVDGKEKDWAKTYPKGRGMAGTFYINY
HCYEYVFPLLALAHYQKLAEGS
>A0A538P7A5|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia bacterium|TrEMBL
MIRGLNHTGLDAAIGRSQQHLLGLQTPEGYWAGELMVDSTLVSDMIAYHHWDGKVDKEWQ
RKGVNHLFSMQLPDGGWNIYYGGPSDVNATIKAYLALKLAGLPATDPRLLKARQVALSLG
GVPRMNTFSRLYLALLGLFPWDYVPTIPCEVILIGKWFHVNFWEMSSWTRSMLVPLSIIN
HFKPTRGLNHITLDELYPEGYHERDLALPPDPQGFTWRNFFIWLDKLHKFAERFAQFNIH
PFRKRALKKAEQWMIERCEGSDGLAAIFPAMLNALIALKALGYPDDHPEVIRAERELKRL
ERETEDDVRIEPCFSPVWDTAIVTICLRESGVSENHPALKRAADWLISKEIRFRGDWQYK
NPAKVEPSGWAFEYENKWNPDVDDTAMVLLALRKVPTDHPARRDASFKRGLDWMMSFQCK
DGGWGAFDKDCTKNILEKVPFADHNAMLDPECADITARILELLGYQGTGLNNPQVARAVQ
FVCEQQEQDGSWYGRWGVNYIYGTWQVLRGMRALNWNMNEPWLLKARDWLESVQHEDGGW
GERCNTYDDPVFKGQGPGTASQSAWAVMGLCAFDDPYRPGLLRGIEYLIRTQNEDGSWTE
HETTGTGFPKVFYLKYDMYRNAWPVLALATYRNLLDNAKGKANAEVNGSAGAFVPEEAVV
PR
>A0A3N7ZU91|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp9142|TrEMBL
MNDLTEMATLSAGTAPAGLDAAVASATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELERKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFVDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AADGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPSRAI
ARKSVEKLLVVQEDEAYCQPCLSPVWDTSLAAHALLETGDARAEEAVIRGLEWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAVAMDRVQKLRQNDAFRDSIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCALNAAGLTPDDPRVKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNHPAVARGVEYLV
ANQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDDTTRVTVGL
>A0A5E6M9R8|squalene-hopene cyclase|EC 5.4.99.17|Methylacidimicrobium tartarophylax|TrEMBL
MRSGKLYSQPSEREAQTKPVLVIEETLTHPQAIGLAIARAQNYLLSTQKPDGYWVGELFA
DVTLACDRILLMHWLAKVDYRKQARFVKHILDRQLPDGGWNIYPGGPSELNATIKAYVAL
KLAGFAPEDPVMERARSTILRLGGIPKSMTYTKLGLALLGIYPWHQLPVIPPEIVLLPNW
FPFHLYKMSAWTRTMLVPLAIIHHFKPTRQLPAHLRLHELFPAGTEQEGISWIWSTKFLS
KRNVFLLCDKLLQIWDRSPWKLLRKRALKKAEEWIVQRMGQGSDGLGAIFPAMHYAIVAL
KALGYPEENPLYQKALRDFEGLEVDEGEERDFRVQPCVSPVWDTAVAGVALGRSGLAANR
AELRKAAAWLMEREIQVRGDWYVNNPHPECSGWAFEYNNVYYPDVDDTLMVLLALLRIET
DDEEKKQEVIERALRWVISFQCRNGGWAAFDKDVNSPWLEDVPFADHNAILDPPCSDITA
RALELAGMRGIKRSESFVQRGIRFLKETQEADGSWFGRWGVNYVYGTWQSLRGLRAIGED
MNQQWILRARDWLESCQNEDGGWGETPDSYENPQLKGRGPSTASQTAWAVMGILACGEVD
RPSLQRGVAYLLRKQDPDGSWPEEFLTGTGFPGVFYLKYDMYRNAWPLLALSEYAQALSL
AKEQTENWVRATLSIAVRSRSSAGRLG
>A0A7Y6C4L5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces odorifer|TrEMBL
MTATTNGPAGAAPSRPAPARTTATTTDTAAPDAAAVEAAAERARARAADHLLGLQSPEGW
WKGDLDTNVTMDAEDLLLRQFLGIRDEATTRSAALFIRGEQREDGTWATFYGGPPDLSTT
VEAYVALRLAGDSPDAPHMTRAAHWVRSQGGIAEARVFTRIWLALFGWWPWDRLPELPPE
LIFLPPWAPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPADPAPRARFAP
LASWNGAFQRLDRALHAYRKVAPRALRKAAMATAGRWIVERQENDGCWGGIQPPAVYSMI
ALHLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALADAGVPAD
HPQLVRAADWMLGEQIERPGDWSVRRPHLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVR
HPDTARMERAISLGVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDPPSADVT
AHVVEMLAAEGLAADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALIDAGLP
TTHPAVRRAVAWLESVQNDDGGWGEDLRSYREQGRMARGASTASQTGWALMALLAAGERE
SRAARRGVTFLAETQHEDGSWDEPYYTGTGFPWDFSINYHLYRQVFPLTALGRYTRGAAP
EGA
>A0A6G2N9A6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4945|TrEMBL
MTATTDGSTGAATPPATTASAPLHLSPEASEAHEATARATRRAVDFLLDRQSDEGWWKGD
LATNVTMDAEDLLLRQFLGIRDEATTQAAALFIRGEQQEDGTWNTFYGGPGDLSATIEGY
VALRLAGDSPEAPHMRKASAFVRARGGVARARVFTRIWLALFGWWKWEDLPEMPPELMFF
PKWAPLNIYDFGCWARQTIVPLTVVCAQRPVRPAPFALEELHTDPADPNPAQPAPPVASW
DNVFHKLDKMLHGYRKVAPRRVREAAMRAAATWIVERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVLRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATVALADAGVPADHPQM
IRAADWMLAEQIVRPGDWVVRRPDLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVAHPDA
TRVDKAVRRAVDWNAGMQSKNGAWGAFDADNTSPFPNRLPFSDFGEVIDPPSADVTAHVV
EMLAEEGLAHHPRTRRGIEWLLENQEANGSWFGRWGVNYVYGTGAVVPALVAAGIPAAHP
AIRRSVSWLGQVQNEDGGWGEDLRSYQDTAWHGRGHSTASQTAWALLALLAAGERDSEQV
RRGIAYLVETQTEDGTWDEPWFTGTGFPWDFTINYHLYRQVFPVTALGRYLNGTGPGEN
>A0A7W4IP86|squalene-hopene cyclase|EC 5.4.99.17|Gluconacetobacter dulcium|TrEMBL
MMVNATDTLERPSAGAADPVVPMIEIDQAVDSAHAALGRRQNDDGHWVFELEADATIPAE
YVLLEHYLDRIEPDLEARIGVYLRRIQGDHGGWPLYHGGRFDLSATVKAYFALKAIGDDI
DAPHMARARAAILDHGGAERSNVFTRFQLALFGEVPWHATPAMPVELMLLPRKALFSVWN
MSYWSRTVIAPLLVLAALRPRAVNPRDVHVPELFVTPPAQVRDWIRGPYRSTLGRVFKYV
DKVVRPGERLIPEATRRRAIKAAVDFIEPRLNGVDGLGAIYPAMANSVMMYRALGVPDSD
PRAATAWESVRRLLVENGDEAYCQPCVSPIWDTGLAGHAMIEAASGPDGIRPHETKKKLA
AAAEWLRSRQILDVKGDWAINCPDVAPGGWAFQYNNDYYPDVDDTAVVGMLLHREGDPAH
HDAIERARQWILGMQSTNGGWGAFDIDNNMDFLNHIPFADHGALLDPPTADVTARCVSFL
AQLGHPEDRPMIERAVAYLRSDQEAEGCWFGRWGTNYIYGTWSVLCALNAAGVSHDDPAI
VRAVDWLRSVQREDGGWGEDCATFEGATPGLYTESLPSQTAWATLGLMAAGLRDDPAVAR
GMAYLARTQKEDGEWDEEPYNAVGFPKVFYLRYHGYRQFFPLMALSRYRNLESSNTRRVA
FGF
>A0A3S0HBR6|squalene-hopene cyclase|EC 5.4.99.17|Hyphomicrobiales bacterium|TrEMBL
MTAAARIETYAPVGAEALEASIQNAKRALLALGKTDGHWCFELEADTTIPAEYVLMRHFR
AEPVDAELERKIGVYLRRTQSERHGGWPLFQDGDFNISASVKAYFALKMIGDDIEAPHMV
RARSAILAHGGAATSNVFTRSLLALYGEIPWRGVPVMPIEIMLLPKWFPFHLDKISYWGR
TVLVPLLVLMTKKPKAKNPKGVRIQELFVTPPEEVKVWPKGEHQTWPWAHIFGEIDKLLR
VLEPHMPKRSRELSIELAEKWTTERLNGVDGLGAIFPAMVNSLLMYDVLGAPESDQRVKD
ARESIERLLVVNETEAYCQPCVSPVWDTSLVAHALLETGDPDARERARQALDWLAPLQVL
DVKGDWAVQRPDLRPGGWAFQYANAYYPDVDDTAVVATAMDRLTANESANPYAERIARAK
EWIVGMQSKNGGWGAFDADNAYHYLNHIPFADHGALLDPPTVDVSARCISLLAQLGETAE
TSDCLKRGVDYIIKDQEKDGSWFGRWGANYIYGTWSALCALNAAGLPHDHDAYRRAVNWL
VSIQNPDGGWGEDLASYKLDYKGYEQAPSTASQTAWALLALMASGDVEHPAVARGVAYLQ
ATQAEHGLWNEARFTATGFPRVFYLRYHGYAKFFPLWALARYRNLVGTNSKLVTVGL
>A0A5B0H9J9|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia panacisoli|TrEMBL
MNDLSQAQALDADLPESAGASLDAPAIATQAQTQVQTQAEKQAAVTPTASLDVAITRATD
AILAAQKPDGHWVYELEADATIPAEYVLLVHYLGETPNLELEQKIARYLRRIQLPNGGWP
LFTDGALDVSASVKAYFALKMIGDPADAEHMVRAREAILAHGGAEHVNVFTRILLALFGV
VSWRAVPMMPVEIMLLPMWFPFHLSKVSYWARTVIVPLLVLNAKRPLARNPRRVRIDELF
RGAPVNTGMNARAPHQHAGWFGFFRGVDAVVRALDGLFPKATREHAVRAAVAFVDERLNG
EDGLGAIFPAMANSVMMYDVLGYPADHPNRAIARQSIDKLLVIKDDEAYCQPCLSPVWDT
SLAAHALLETGEAHAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYNNPHYP
DVDDTAVVVMAMQRSAALTQSAVDRQAIARAREWVLGMQSSDGGWGAFEPENTQYYLNNI
PFSDHGALLDPPTADVSGRCLSMLAQLGEMPQNSEPAQRAFAYMLQEQESDGSWYGRWGL
NYIYGTWTALCSLNAAGMAHDDPHMRRAVQWLLSIQNPDGGWGEGGESYKLDYRGYERAP
STASQTAWALMGLMAAGEVDHEAVARGVDYLQREQREHGLWDETRFTATGFPRVFYLRYH
GYRKFFPLWALARFRHLKRNGLTRVAVGM
>A0A7C5RR24|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MGVTAVASYLGPGERRKLEEAASQAANRTIEYFLRTQHPEGWWWGKLESNVTMAAEYLLL
TQFLGVREEKRWHKVVNYLCREARPDGTWSIYYGGPPDLNSTIECYFSLKLAGIPLDDPL
LEKARAFILSQGGVPKARIFTKLWLALFGQWPWKALPAMPPEFMFLPTWFPLNLYEFASW
ARATIVPILIIWAKRPVRPVPEFARIDELFPGPPQKVARPLSPPSSLISWKGFFWGLDRL
LHHYERRPLGLLRKAAIKEAVKWIIARQEADGAWGGIQPPWVYALIALSVLGYPLDHPVM
KRGLEAFEGAFKVEDDQLYWPQACISPVWDTALAMIGLLDAGLPPDHPALQRAAHWLLKE
QVLTGGDWQAKVKGVEPGGWAFEFDNDYYPDVDDTAEVMMALYRTRLANEARKEMALDRA
LAWVLGMQCSNGGWAAFDRDNVRGVVTHIPFCDFGEVLDYPTEDVTAHVVEMLGLLGYGP
HFPPVARALRFLRRLQDPEGPWWGRWGVNYIYGTGAVLPALKAIGEDMTRPYVRRAVGWL
LGCQNSDGGWGESCASYEDPSLKGKGESTASQTAWALLGLLAATPEDADGLLWQAIAKGV
TFLVETQNEDGTWEEPQFTGTGFPRDFYINYHLYRNYWPLMALGRALTALRGE
>A0A6L7PZ84|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MLRSTKIRRDVESSGAVPSQAAVDGAISKLHGYFRGIQSDLGYWWGELESNNTMEAEYVM
LSRFLGHHNPERERHIVNYLLSKQLADGSWSIYYGAPGDLSTSVECYFALKLCGEDPESD
AMSRAREFILQRGGLPRVRVFTRIWFALFGQWDWEGTPRLPTEMMLLPDWAPLSIYRFAS
WARGCIVPLSIVLSKRPVRPIPPEQAIDELLPNGRAGTDYTLPKPPGFTLPRLMHIIDET
LGKIYYRVKKFNPLTKAAEKRAIRWILEHQEDDGSWGGIQPPWVYSLIALSICGFPNDHP
AIKRGFHGLDGFGIQKDDRWTIQGCISPVWDTCLVVQALAESGVSTDDPMLASATNWLVD
KQILVGGDWQVQARQLQPGGWAFEFHNNCYPDIDDTAEVVLALRLGKLPDDKDFLRQQAI
DRALDWVTGMQNRDGGWASFDKNNNHAYVTALTFSDFGEVLDPSSADVTAHVLEMYGKLG
YKINTESLQSAYRYLRFEQEDNGSWFGRWGVNYVYGLGAVLPALEAIGEDMKQPYVRRAV
QWLLDHQNDDGGWGESCASYVDIEQHGVGPSTASQTAWALMALIAAGDGDHPAAHRSVDY
LLRTQQPDGHWEEPYFTGTGFPGYIKGERVSRVPKPGERGFQGMELSAGFMINYHLYRNT
WPLLALARYRNRIYTEPQPCSQSATYESQKFLPQSRYQRRPAVD
>A0A7X9ZB65|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. RLA2-12|TrEMBL
MTATTDGSTGALPPRAAAASEIHPETTPVAAGTVETRDVATHAIQRATDFLLSRQDAEGW
WKGDLETNVTMDAEDLLLRQFLGIRDETTTRAAGLFIRGEQREDGTWATFYGGPGELSTT
IEAYVALRLAGDAPDDPHMARAAAWIRERGGIASARVFTRIWLALFGWWKWDDLPELPPE
LIYFPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDAGDPNPVKPLAP
AASWDGVFQRLDKALHQYRKVVPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVI
ALHLLGYDLQHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPAD
HPQLVKAADWMLGEEIVRPGDWAVKRPHLPPGGWAFEFHNDNYPDIDDTAEVALALRRVR
HHDPERVEHAIGRGVRWNLGMQSKDGGWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVT
AHVVEMLAVEGLSHDPRTRRGIEWLLAHQEPDGSWFGRWGVNYVYGTGSVLPALVAAGLP
ASHPAIRRAVAWLETVQNDDGGWGEDLRSYHEVAEWSGRGASTASQTGWALLALLAAGER
ASKAVERGIAWLAETQLADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEP
SFVHGESFAEVKGG
>L7F854|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces turgidiscabies Car8|TrEMBL
MPLHEGEAMTATTDGSTGALPPRAASASETETDTNTPVAAGVQDAAERAMRRATDSLLAR
QDSQGWWKGDLETNVSMDAEDLLLRQFLGIRDEQTTQAAALFIRGEQRDDGTWATFHGGP
ADLSATVEAYVALRLAGDEPEAPHMARASAWIRDRGGIAAARVFTRIWLALFGWWKWDDL
PELPPELIYFPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLEELHTDPDLPNP
GKSLAPLASWDGAFQRLDKVLHGYRKVAVRRLRKAAMNAAARWIIERQENDGCWGGIQPP
AVYSVIALHLLGYDLEHPVMRAGLDSLDRFTVWREDGARMIEACQSPVWDTCLAVIALAD
AGLPADHPQLVKAADWMLGEQVVRPGDWSVRRPELPPGGWAFEFHNDNYPDIDDTAEVVL
ALRRVRHHDPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSTLPNKLPFCDFGEVIDP
PSADVTAHVVEMLAVEGMSHDPRTRRGIEWLLAEQEPNGAWFGRWGVNYVYGTGSVVPAL
TAAGLTAAHPAIRRAVGWLEKVQNDDGGWGEDLRSYQDSAGWSGRGASTPSQTAWALLAL
LAAGEHDSKAVERGVEWLAANQLPDGSWDEPYFTGTGFPWDFSINYHLYRLVFPLTALGR
YVHGEPFADVKGG
>A0A5C6VEN5|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia azotifigens|TrEMBL
MNDLSMTQTLGEALPQTLIDDHAPVAAALATGAAPVDALDAAVTRATDAILAAQKDDGHW
VYELEADATIPAEYVLLVHYLGETPNVELEQKIARYLRRIQLPNGGWPLFTDGAMDVSAS
VKAYFALKMVGDAEDAEHMVRARECILANGGAEAANVFTRILLALFGVVTWYAVPMMPVE
IMLLPKWFPFHLSKVSYWARTVIVPLLVLNAKRPVARNPRGVRIDELFRGAPVTTGLLPR
SGHQSKSWFAFFRAVDGVLRVTDGLFPKASRERAIKAAVDFVDERLNGVDGLGAIFPAMA
NSVMMYDVLGYPADHPNRAIARESIEKLLVIHEDEAYCQPCLSPVWDTSLAAHALLETGD
PRAEQAAEGGLAWLRPLQILDVRGDWTSRRPDVRPGGWAFQYNNAHYPDVDDTAVVALAM
HRSAALTKSNVDANAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPP
TADVSGRCLSMLAQLGEMPATSEPARRAYNYLLKEQEDDGSWYGRWGMNYIYGTWTALCA
LNAAGISLEDARIKRAAQWLVSIQNADGGWGEDGTSYKLDYRGYEKAPSIPSQTAWALLG
LMAAGYVDHPAVARGVEYLQSEQRDHGLWDEERFSATGFPRVFYLRYHGYRKFFPLWALA
RYRNLTRAGQKRVTVGM
>A0A532CBI3|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp|TrEMBL
MKLIRALLDRLSESFVVSVSEKLELATEPSNSPPLRLVSDKPLLSVPVDTIPRRSAGHSV
SQVDALDDAVRRSQAWFVSRQDVSEGYWVAELEADTTLTSEYLMLRRFLDRVDPERERKA
VSYLRAMQLPDGGWPIFYGGPSEISASVKTYFALKLSGVSADEPCMLRARDRILAMGGVV
CANVFTKITLALFDQYDWKGVPSMPPEIMLLPKRFYFSIYAISYWSRAVLIPLLVVFAKQ
PVCRIPREQGIDELYLSPRAQIHYRDVPPFNKEQRWFTPHNFFVQLDRILKLYDQMPLSW
LREKALHEAATWMLEHLKGSGGLGAIYPAMANSIVALRCLGYEVDDPLVQKALREIESLE
VYDTASIDNQQVETLHLQPCHSPIWDTALLMNALIETGMPQDHPSLQKAGAYLLSRQTTT
VGDWKFSSPNAKPGGWYFQFENEFYPDVDDSAVVLMALSKVRIGQAPESQASIRRGMDWV
LAMQGSDGGWGAYDKDNNRIVFNYIPFADHHALLDPSTSDLTGRCLEMLAALGYDQTHPA
VGPALRFLKREQEPDGSWYGRWGVNYIYGTWSVLAGLRAIGVDLSDPAICRAVAWLESKQ
NSDGGWGESGLSYGDPAWSGKGDSTPSQTAWAIMGLMSAGMADAFSVARGIQYLLRHQTK
EGSWEEVRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRTRGTMRADEVRQQVFASGC
HRADH
>A0A6B2ZLV0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID7909|TrEMBL
MTATTDGSTGAVDPRAASARRTTTESTIAADGVLAAARRAAERSVEHLLGRQDEQGWWKG
DLATNVTMDAEDLLLRQFLGIQDPATVRAAAGFIRGEQLGDGTWATFHGGPADLSTTIEA
YVALRLAGDRPEDPHMVRAAGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMF
FPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPANPNPPKRPAPARS
WDGLFQRLDKALHVYHRFAPRRVRRVAMNSAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVMRAGLESLDRFAVWREDGTRMIEACQSPVWDTCLATIALADAGVAPDHPA
LVRAADWMLAEEIVRPGDWAVRRPGLEPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPD
QARVDAAIERGVRWNVGMRSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHV
VEMLAVEGRAADPVTRRGIEWLLAEQDPGGGWFGRWGVNYVYGTGSVVPALTAAGLPPSH
PAIRRAVEWLESVQNDDGGWGEDLRSYSEEKWIGQGASTASQTAWALLALLAAGRRDTVA
VTRGIAWLTETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFAGR
TPTREGA
>A0A6N0X0W9|squalene-hopene cyclase|EC 5.4.99.17|Sphingomonas sp. CL5.1|TrEMBL
MATLHHTLDPLAAVDAAVDRAAAALHRAQRDDGHWVFELEADCTIPAEYVLLRHYLGEPV
DAELEGKIARYLRRIQSAEHHGWGLFHAGGFDVSATVKAYYALRMIGDAPDALHMVRARN
AVLAAGGAEAVNVFTRIQLALFGAGPWSAVPTMPPELILLPRWFPIHLSKVSYWARTVIV
PLLVLGAKKPLARNAKGVRVDELYTGHTAQARTQAADPKWLWTHGFNTLDRLLKLGDGLW
PRRLRQRALAACEAWVRERLNGEDGLGAIYPAMANSVMMFDALGYPESDPGRAIARKSVE
NLLVIHEDEAYCQPCVSPVWDTALAAHAMLEAGGEENVARAGVALDWLRPRQVLDVAGDW
AQERPGVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRAGVADRMPIDRGVEWTVGLQSRNG
GWGAFDADNDYDYLNNLPFADHGALLDPPTADVSARCVSMLAQLGEHRDSPRMAAALDYL
RREQEPDGSWFGRWGVNYIYGTWSVLCALNAAGLGPDEPMVARATAWLTAIQNPDGGWGE
DCDSYALDRTGHAPAPSTASQTAWALLGLMAAGEVDSDAVRRGVDWLAAHQEADGLWGQE
HYTGGGFPRVFYLRYHGYPKYFPLWAMARYRNLKRSNTRRVTVGM
>A0A4U5X121|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces galbus|TrEMBL
MTATTDGSTGALPPRAASASDTTRITTPEAAGVPRTAERAMRRATDFLLSLQDDEGWWKG
DLETNVTMDAEDLLLRQFLGILDEATVGAAALFIRGEQREDGAWATFYGGPGDLSATVEA
YVALRLAGDTPDAPHMARASAWVRERGGIAAARVFTRIWLALFGWWKWEDLPELPPELLY
FPKWFPLSIYNFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPANPNPPRPPAPVAS
WDGVFQRLDKVVRGYRSVAVRRLRRAALNSAARWIIERQENDGCWGGIQPPAVYSVIALY
LLGYDLEHPVMRAGLESLDRYAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQ
LVKAADWMLGEQVVRPGDWSVRRPELPPGGWAFEFHNDNYPDMDDTAEVVLALRRVRHHD
PERVENAIARGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGYAHDPRTRRGIEWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALTAAGLSTEH
PAIRRAVSWLERVQNDDGGWGEDLRSYQDPGRWSGRGASTASQTAWALLALLAAGERESR
AVERGVEWLARTQREDGGWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGEPFAN
QAVKPRTAQKPVASAAEAEAG
>A0A523NJD3|squalene-hopene cyclase|EC 5.4.99.17|Nitrospina sp|TrEMBL
MSPDNPLEASTDVARPEPVPSPKNLMQAVERSRNHLLSRQYPEGYWVAELESNATMVAEY
VFFLWFMGLHNDPAPREKSKNYLLKHQQADGGWSLYYGGPSDISVTIEAYIALKMTGVAM
AAPEMVKARQCIAAKGGVRSARVFTKIFLAMLGQTTWEFVPAMPVEIILLPNWFYFNIYE
MSSWSRSTVVPLTLIYSQQPVWPLPPNHSVPELFTEADRDLAVRSPQPGLNWGNVFLTLD
KVLKFVGRSPWKPLRRIAIRRALQWTLDHQEPEGDFSGIQPAMLNSLLALKVLGYENDSS
AVIKGLEAIDRFIIDRGDHLVFQACVSPLWDTALALNALMDAGLPENDPAVVKAAEWMLK
KQVTRPGDWTIKNPHTPPGGWAFEFYNESYPDTDDTAEILMALHRIPFADPAWKEKECRR
ALTWLLSMQSQNGGWGAFDQDNDHRLFNLIPFADHGAMLDAPTVDVTGRVLWLMGRLHTD
RNHPQVQKALKFIRGEQEADGCWFGRWGVNYIYGTWLVLCGLQSMNEDMSQPYIRKAVDW
MKAHQNEDGGWGETCESYRNPQLRGQGTSTASQSAWALMALMETGETHSPEAQRGVDFLI
RTQLDDGSWHEDHFTGTGFPGHFYIKYHMYAQFFPLMALARYRYYVEHGHVPPRRQSGKA
RS
>A0A7Y9RIV6|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. IAR9|TrEMBL
MDSVNATSREALQPGTLQPGILQSGILESSIASATQGVLDFQQADGHWVFELEADCTIPA
EYVLLRHYLAEPVDAVLEAKIANYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGD
PVDAPHMVRAREAIHARGGAIHSNVFTRFLLAMFGVVTWRAVPVLPIEIVLLPFWSPFHL
NKISYWARTTMVPLMVLAALKPLAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFVLF
RSLDAVLRVIEPMFPKALRKRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKD
ENFPPRAITRRGIDKLLVIKDDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLD
WLIPKQELELKGDWAVKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGATGY
DAAIDRGREWIEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISML
AQLGETEKTSKHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDHGDPM
IRKAADWLASIQNKDGGWGEDAVSYRLDYRGWEAAPSTASQTAWALLALMAAGEVDHPAV
ARGVEYLIATQNKKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRV
VGVGM
>A0A661KE85|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
YVSSPNGRKKPSNCMNFLIFSRHIGKLLFKAPFRPLRNTALKRAEEWIVDHQEESGDWAG
IQPAMVNSLLALFSLGYPLDHPVIQKGLEALETFLIDKGDEVVLQSCISPVWDTALNCLA
LVEAGIPPKYPAIQLAAEWLLKQQIFRGGDWQVKRPDLEPGGWAFEFHNDHYPDVDDSAV
VLMALQRAVGDNPSAKCAIERGINWVLGMQSSDGGWGAFDVDNNKEYLNRIPFADLEAMI
DPSTADLTGRVLQMMGYYGYDKDHPVAKKAIRFLRKIQEPDGSWWGRWGVNYIYGTWSVL
SGLESIKEDFSQPWIQKAVQWLKNCQNPDGGWGETCESYKNPSLSGHGPSTASQTAWSLL
GLMAAGEWESPEISRGIQYLLKNQQPDGTWEEEYFTGTGFPKYFMLRYHNYRNCFPLMAL
GRYYGWLQDQLRLPGKTSLQMS
>A0A534PUX2|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MGSRDAGANGGARRGQRGDRQPDLPRRNARRQTDADGQGHLRLPQRPHARLPRHRHERRR
RGGRRRRTPARVRARRAWRALHPRPRQPDHARIPRGAGVHQRPARAAHPPAARGRPGPGA
CRRFRLRAAVAPRAAGAHRRSADRARDHVRQLSPRRARAGAAPEAGARSAGQGGALVPGC
RPREDRVVIGPERDATVASALPAPPAAGEASSSDGLQLDLVVERAQSWFFREQFDEGYFW
AELESNATMDAEYLLLTQFLGARDDQIWRGVAQDIRNYQREDGSWALYHGAPGDLSTTIE
CYFALKLAGDGADARHMRKAREFARARGGIACARTFTRIWLALFGQYPWDELPAMPPELM
LLPKKAPLNIYRFSSWARGTIVPLLVLMDARPVRSVPEAARLDDLMVPAAQPARARDFVD
RAFLALDRALHLYDRLPVHPLRARALDEAERWILAHQEADGSWGGIQPPWVYSLMALHAR
GHSLDSPAVEKGLRGMHERWMIRRADGTVRVQACLSPVWDTGLALLALCESGVPAEDPRV
QRAAQWLLREEIRVPGDWCVQVPGVEPSGWAFEFENDLYPDVDDTAVVLLALERAGAVDP
ALRERAVSWMLAMQSANGGFAAFDKDNTSRLSALIPFADFGEMIDPPSVDVTAHVLETLG
AFGFGRRDGRVRRALEYLYRGQEKEGSWFGRWGVNHLYGTGAVLPALAAVGEPLDGLAAR
RAVRWLEQRQNPDGGFGETCASYVDRAMRGRGESTPSQTAWALLALVAAGRTDTLAARRA
ARFLADRQRTDGAWDEEQFTGCGFPGYGIGEERGARIREGRELSAGFLIRYHLYRNCFPL
LALGRYRAGMTT
>T2AY40|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
RPSWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPGRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWFGSWG
>T2AZJ7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLAMHAVLEANSVPDKIIMKKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWFGRWG
>T2B005|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLNRGQEANGSWYGRWG
>T2AZC6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSGPDKIIIEKAANWLVGRQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVGARCLSMMAQLGYGPDNQAVARAIGYLKRVQEVNGSWFGRWG
>T2AZB6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAAHAVLETLGGNTLLLNKPCDWLSKLQIKEHTGDWGWRRKGLGPGGWAFQYN
NKFYPDVDDTAVVGMALHRQNPEKYADTISRAEEWIIGMQSSNGGWAAFDADNEYYLLEN
LPFADHRALLDPPTADVTARCISFLTQIGTSNNHPISRGLEFLKRNQEEDGSWYGSWG
>T2B0J0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PVWDTGLSGISLLESGLTLKDIAIKKACTWLEKKQILEMKGDWVANNKKLLPGGWAFQYE
NDFYPDVDDTAVVAMFLDRAGYQNKKRLERACNWIIGMQSKNGGWGSFDKDNTYHYLNNI
PFADHGALLDPPTADVSARCISMLSQI
>T2AZL2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTCIAHLALLESGIDPEDSMVQSSARWLMDKQIYATADWQVRAKGTRPGGWSFEFD
NLIYPDVDDASIVVMALDQVRLPEAEEPRRADSIQRGVEWMAGMQSKNGGWAAFDKDNNK
KYLTKIPFSDFGETLDPPSVDVTAHLLEMYGRLGYTKKDRAVDRGFAYVISEQEEDGSWY
GRWG
>T2B0F5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGFNGLSLLESGLTLKDSSIQKACKWLGKKQILEIKGDWIVNNKNLLPGGWAFQY
ENDFYPDVDDTAVIVMFLDRAGYQNKKRLEIACNWIIGMQSKNGGWGAFDKDNTYHYLNN
IPFADHGALLDPPTADVSARCISMLSQINKKNNKKIIQKGVKFLKNEQENDGSWFGRWG
>T2B0C9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTCIAQLALLESGIDPEDPMVQSSARWLMDKQIYAAADWQVRAKGTRPGGWSFEFD
NLIYPDIDDASIVVMALDQVRLPEAEEPRRADSIQRGVEWMAGMQSKNGGWAAFDKDNNK
KYLTKIPFSDFGETLDPPSVDVTAHLLEMYGRLGYTKEDRAVGRGFAYVISEQEEDGSWY
GRWG
>T2AZ91|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTCIAQLALLESGVAPDDPMVQSSARWLMDKQIFAGGDWQVQAKDTRPGGWSFEFD
NLAYPDIDDASIVVTALERVRLPGAEEPRRADSIKRGVERVAGMQCKNGGWAAFDKDNNE
KYLTKIPFSDFGETLDPPSVDVTAHLLEMYGRLGYTREEQAVDRGFEYVIGEQEENGSWF
GRWG
>T2AZ76|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQY
SNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYLN
EIPSADHGALLDPPTVDVTGRAITLLSLADKKIYAKNIKGGVDYIKSEQEEDGSWFGRWG
>T2AZR5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPGLSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTKNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHLYL
NEIPSADHGALLDPPTVDVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSW
>T2B038|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTCIAQLALLESGIDPEDPMVQSSARWLTDKQIYAAADWQVRAKGTRPGGWSFEFD
NLIYPDIDDASIVVMALDQVRLPEAEEPRRADSIQRGVEWMAGMQSKNGGWAAFDKDNNK
KYLTKIPFSDFGEALDPPSVDVTAHLLEMYGRLGYTKEDRAVGRGFAYVISEQEEDGSWY
GRWG
>T2AYI5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
LQIKEHTGDWGWRRKGLRPGGRAFQYNNKFYPDVDDTAVVGMALHRQNPEKYADTISRAE
EWIIGMQSSNGGWAAFDADNEYYLLENLPFADHRALLDPPTADVTARCISFLTQIGTSNN
HPISRGLEFLKRNQEEDGSWYGRWG
>A0A7Y6FPU1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. CAI-78|TrEMBL
MTATTNGPAGAAPSRPAPARTTATTTDTAAPDAAAVEAAAERARARAADHLLGLQSPEGW
WKGDLDTNVTMDAEDLLLRQFLGIRDEATTRSAALFIRGEQREDGTWATFYGGPPDLSTT
VEAYVALRLAGDSPDAPHMTRAAHWVRSQGGIAEARVFTRIWLALFGWWPWDRLPELPPE
LIFLPPWAPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPADPAPRARFAP
LASWNGAFQRLDRALHAYRKVAPRALRKAAMATAGRWIVERQENDGCWGGIQPPAVYSMI
ALHLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALADAGVPAD
HPQLVRAADWMLGEQIERPGDWSVRRPHLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVR
HPDTARMERAISLGVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDPPSADVT
AHVVEMLAAEGLAADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALIDAGLP
TTHPAVRRAVAWLESVQNDDGGWGEDLRSYREQGRMARGASTASQTGWALMALLAAGERE
SRAARRGVTFLAETQHEDGSWDEPYYTGTGFPWDFSINYHLYRQVFPLTALGRYTRGAAP
EGA
>A0A1S1NYH7|squalene-hopene cyclase|EC 5.4.99.17|Methylorubrum extorquens|TrEMBL
MREAAVSKVETLQRPKTRDVSLDDVERGVQSATRALTEMTQADGHICFELEADATIPSEY
ILFHQFRGTEPRPGLEAKIGNYLRRTQSKVHGGWALVHDGPFDMSASVKAYFALKMIGDD
IEAPHMRAVRKAILQRGGAANANVFTRILLALYGEVPWAAVPVMPVEVMHLPKWFPFHLD
KVSYWARCTMVPLFVIQAKKPRAKNPRGVGVAELFVTPPDSVRTWPGSPHATWPWTPIFG
GIDRVLQKTQDHFPKVPRQRAIDKAVAWVSERLNGEDGLGAIFPAMVNSVLMYEVLGYPP
EHPQVKIALEAIEKLVAEKEDEAYVQPCLSPVWDTALNSHAMLEAGGHQAEANARAGLDW
LKPLQILDIKGDWAETKPNVRPGGWAFQYANPHYPDLDDTAVVVMAMDRAQRQHGLVSGM
PDYSESIARAREWVEGLQSADGGWAAFDADNNHHYLNHIPFSDHGALLDPPTADVTARVV
SMLSQLGETRATSRALDRGVTYLLNDQEKDGSWYGRWGMNFIYGTWSVLCALNAAGVDPQ
SPEIRKAVAWLIRIQNPDGGWGEDASSYKLNPEFEPGYSTASQTAWALLALMAAGEVDDP
AVARGVNYLVRTQGQDGLWSEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKRGNS
RQVQFGM
>B5GLQ0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces clavuligerus|TrEMBL
MRRSDEQAAVAGAEAVRDAVRLVAASTAALVAEDGRYPGTCESRVLESAAALRLLQLLVP
SDPAVARARGFLCEAGKKERASELDRMVVAAALGTGVPAGPELTDRLLTGFTHFTAVRKR
LLLETLLYLTGAVDRVAEPVWEAFEARHLQVWKQIEMTACKAVLAAALGRPERVTAEDLA
LLAGTVRAGEVFEGNLLDHVLLLHALARHPGHDGPVRTGLATLIARQRPDGGFPLVADMD
PVLTGLAGTALAESGADPAAQARLGDWLAARQHPSGAWNYTAETSQTDIETTSFVLEALA
SIDPARHRGALRSGCAYLAGMQNTDGGLPLYARGNPSEAATTGEAVTAWARTDADRYAAR
IEDAVRFLIDGQCPDGTWGLEWSASEGNVILRAVYALLRATDAGVLPDGLAHRAGKAVDM
AVTRLLTSQNSDGGWGFRPTRHSDAISTAYALTTLSLAGRHQAAPAGAAFLCSRVDTAGR
VDAEYDTYSPRPLMIEITSLPRVYVLRGLVHAARSLAALLP
>A0A6B0XMX4|squalene-hopene cyclase|EC 5.4.99.17|Holophagales bacterium|TrEMBL
MIGPAGVLKERSKTAPARNLNQTIEAAARNLLSSRKEDGHWRFELEGDTILESEYVLLLY
FLGRVDDPRIAACCRRLRSQQMPTGGWATHPGGRVDPSVSVKAYLCLKLAGDDPRSPHMA
AARRAILGAGGLRACNSYTKLYLAIFGLWRWRHAPAVPPEMILLPRWFCFNIYDMSSWTR
AMVVPLSVIWAHRPNVPLDVTLDELETEFVPAPVRPPLIKLFWAQGFTALSALLKLVEWI
GPLPWWRRRALLKAERWLTERIECADGLAAIFGAIVNAVIALRCLGYDVSHPLVQAQLRE
LARFEIEEAGETRLQPCLSPVWDTTLTVNALLDAGVDDGKAPIQEALEWLLDREISVAGD
WRQGSLQEAPGGWCFEYRNDYYPDCDDTAEALLALARVRGRFALEARRQEALARGLSWLL
GMQNPDGGWAAFDRGCDKEVLTFIPFADHNAMIDPSTPDITSRGIRALLAAGLDRREAPV
RRAAGYLLRQQEEDGSWPGRWGANHIYGTGLSLGALGEFACTAPRDSSDALARALRRGRN
WLVRVQNGDGGWGESLRSYEDPTARGRGDSTASQTAWAMLGLSAGVRADPDPREAGPTRA
ALDRAAAFLQERQREDGSWYDHWWTGVGFPGVFYLRYHGYAQYFPLAALAAYRRVRSGSR
G
>T2AZC1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWYGRWG
>R9W2P8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAITGVGHIGDGRAADAGNTADWLISKEVRRKGDWSVKRPKVEPSGWYFELANEF
YPDIDDTAQVLLGLVHARSRNSAKQQASIARAITWLLAMQGKDGGWAAFDVDNNWEFLSA
VPFADHNAMLDPTCPDITGRVLEALVADGVKPNHPAMIRGVEFLRNAVEADGSWYGRWGV
NYVYGTFLALRGLEAAGEDNRDAHILRAGEWIRSIQNADGGWGE
>A0A6L8HVP0|squalene-hopene cyclase|EC 5.4.99.17|Acidobacteriia bacterium|TrEMBL
MKLDAGRDSRAAIARPPVENLAIRAEQAVDAACNYLLNRQTSGGYWVGEVEGDTTLESDY
VLLQLWLHEPGGDGTWNPPTRSLVDAACNRIADQQLEDGGWNIYPQGPANINASVKAYSA
LKLGGHGQYSEQLRRAAKRIVDLGGVEAANSYTKLYLSYFDLYPRSDVPSIPPEIFLLPA
GHQFGIYSISSWSRAMLAPLSILGATRARRRAPIGFSLEELFSGRAAPAPALLSWKRFFL
LLDKAIKFLESTAAGRHRELGIEAARDWMVARLERSDGLGAIFPAMVNSIMALTQLGYDS
SHPLFRAQLAHFDNLILHDERGFRVQPCHSPVWDTALTTHAIGAAKARLGDPARWALGRA
ADWLLAKQASTPGDWAVRNPQAAPGGWFFEYRNDHYPDTDDTAEVLLALEHTSATDPQRQ
LRAEERALEWLAAMQSSDGGWAAFDVDSCTAILNHVPFADHNAMLDPSCVDITGRVLETL
CRRAPGRYRERVLRGVEYIRRAQHEDGCWYGRWGVNYIYGTCFALRGLRAAGVLPWDSAV
IRAGEWVRSLQNADGGWGESPDSYDDPALRARGESTPSQTAWALMALLASEDCESGSVAD
GVRYLLERQTPQGTWAERAHTGTGFPSVFYLRYHMYPQYFPLMALGEYARKKGVAQA
>A0A109EJJ4|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cenocepacia|TrEMBL
MNDLTEMATLSAGAVPADVDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKALDKLLVVQEDEAYCQPCLSPVWDTSLVAHALLETGDARAQEAVLRGLEWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLTQSDTYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGYEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLV
AQQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A6H0CX63|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. DSM 40868|TrEMBL
MTMSAGGVPHAKGPVVAGDAGVTFAFPASGPAEEAARGAVVRAANHLLARQDAGGWWKGR
FTTDVAYDAHDLFLRHLLGVLDERLAKASARWIRSQQSADGSWPLVFEGEGHLGTTIQAY
VALRLAGDGPDEEHMLRCAAWVRERGGAAAAQLTTRVWLALLGWWSWDDLPEVPPEIIAL
PKWAPLNIYSFSSVMRVALVAISVISTHRPARPAPFAIDELFAPRGTSAVAPAPDSGRER
VFRRLNATVRVCSKGIPRPVREAAANACVRWLLERQEEDGSWGACTPMTTWVVLALHLHG
YPSDHPVLKAAWGFLEDCGAWPEDGVRALHTVHSPVWDTCLSATALLDAGLAPGHPALVR
AADWLLTRQADRPGDWAARRPRLSPGGWAFQFHNRTYPDNDDTSEVALALHRVDHPDPTR
VDDALGRAVRWCLGMQSRNGGWAAFDVDNTSTLPARLPFFDFGEFCTDPPTADITAHVVE
MLAALGRARDPRTRRAVRWLLEQQEANGAWYGRWGVNYVYGTGSVLPALVAAGVPRGHAA
VRRAVAWLTSVQNADGGWGESWESYADPARAGRGPSTPSQTAWALLGLLAAGERDSTVVR
DGVRWLTERQTEDGTWEEPHYTGTLVPRAVAAHYAYYGHVFPLMALGRYVRRTGDVSVGR
QRNEATEPDR
>A0A7K3S823|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces parvus|TrEMBL
MTATTDGSTGAANITGAPADDPTDTRTVANDVTDIARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPGDLSATIEAY
VALRLAGDRPDEPHMARASGWIRDQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPDHPNPPRKLAPPTSW
DGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMIEACQSPVWDTCLATIALADAGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARLEAAIARGVRWNLGMQSRNGAWGAFDADNTSAFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLAKHPRTREGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALIAAGLPAGHP
AIRRAVDWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDTASV
TRGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFADRP
DAAEGA
>A0A522B0B2|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
MNRLLGLLTNWSEKILSAAPKRVQQQARQKADRLLRLVGGNPNATPVPPVPPRRQESGQT
LNQGAAVEEAVKRGQQWLLSRQAEPGYWVHELEADTTLTSEYLMLRRFLGLVDKEKERKA
VRYLIDAQLPEGGWPIYYGGPPEISASVKAYFALKLSGVSAGEPFMQKARAAILKSGGVA
RANVFTKIALTLFDQYDWRGIPTMPVELALLRPNPVFSLYDLSYWSRAVLTPLLIVFNFK
PACRIPREEGIDELWCTPREQMDFRHAPPFLRDRSWFTWRNFFITLDGLLRVYEQVVPEG
LRKKALARAAEWMMARMEGQGGLGAIYPAMANSVVALTCLGRSVDDPLVRKALGEIEALE
VHDGDSLHLQPCFSPIWDTPLTMNSLIESGLPSDHPALLRAARWTFTRQCRKAGDWVVSS
PKAEPGGWYFQFENEFYPDNDDTAVVIIALSKLAMPDADVQRDAMRRGIRWTLAMQGSDG
GWGAYDKDNNKLFLNQIPFADHKALLDPSTADLAGRELEMLGALGYDLAHPAAGRAVRFL
RKSQEADGSWYGRWGVNYVYGTWSVLAGLKAIGEDMQAAYVRRAVAWLVSRQNPDGGWGE
SCLSYAEAAAHGVGESTSSQTAWALLGLLCAGEVETISVMRGVNYLLRRQDPQGCWPERM
HTGTGFPRVFYLRYHGYSHFFSLWALSMYRSLKSRGRTRADEIRERNRQSGRFRLA
>A0A7Y6F830|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. CAI-24|TrEMBL
MTATTDGPAGAAKLSATTAGHPDRTTPAPDQVLAAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPSDLSATIEAY
VALRLAGDAPDEPHMARAASWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFL
PSWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPARPNPPRKLAPAASW
DGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIVERQENDGCWGGIQPPAVYSLIALHL
LGYDLEHPVMKAGLASLDRFAVHREDGARMVEACQSPVWDTCLATIALVDGGLRPDHPAL
VKATDWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARVEAAIERGVRWNLGMQSRNGAWGAFDADNTSSFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGRAQHPRTQRGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALVAAGLPAAHP
SIRRAVEWLESVQNDDGGWGEDLRSYREEKWIGHGESTASQTAWALLALLAAGRRDSVAV
SRGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRT
GAAQGV
>A0A6P0ZNN9|squalene-hopene cyclase|EC 5.4.99.17|Sphaerospermopsis sp. SIO1G2|TrEMBL
QILDYGDWDVKNKQGKPGAWAFEFDNRFYPDLDDSAVVVMALYQSKLTNENLKKQTIKRA
LYWIESMQCQPGGWAAFDIDNNQEWLNSIPYGDLKAMIDPNTADVTARVLEMLGFCNLSI
PANKLTKALNYLINEQEQEGCWFGRWGVNYIYGTSGVLSALTLIDPQKYRAEIEKGATWL
MKVQNSDGGWGETCFSYHDPSLKGKGDSTASQTAWAIIGLISAMTVMGKKALPTIEQGVN
YLIKTQNSDGTWHESYFTGTGFPCHFYLKYHLYQQYFPLMALGRYQAVI
>A0A558A3Y3|squalene-hopene cyclase|EC 5.4.99.17|Amycolatopsis acidiphila|TrEMBL
MTQIAETPSALRNPADTLARAVAHLKGLQEDGGWWKGELETNVTMDAEDLLLREFLGIRT
ATETEEAARWIRSQQRADGTWATFYGGPGDLSTTVEAWVALRLAGDSPAAPHMRSAQKFV
LANGGLEATRVFTRIWLALFGLWSWDELPNMPPELIFLPSWFPLNVYDWGCWARQTVVPL
TIVATLRPVRPMAFGVDELRTGKRARTNLKPWTWAGAFGYLDKALHTYAKLPVKPMRGLA
MRQAAEWILARQEADGSWGGIQPPWVYSLLALHLLGYSFEHPAVKAGFEGLDGFIIREET
PDGVVRRLEACQSPVWDTGLAMTALHDAGVPADDPTLLKAADWLLGEEIRVTGDWAVKRP
TTPPGGWAFEFANDVYPDTDDTAEIVLALRRTAYPDRPRLKEAVDRATIWLRGMQSSDGG
WGAFDADNTRTLTTKLPFCDFGAVIDPPSADVTAHVVEMLAAEGLTGTRECRRGVQWLLD
AQEDNGSWFGRWGANHLYGTGAVVPALVAAGVSPADPVIRRAVAWLARCQNPDGGWGEDL
RSYRDPAWIGKGDSTASQTAWALLALLAAGERGSSTVERGVRWLAETQRPDGTWDEPQFT
GTGFPGDFYINYHLYRLVFPVSALGRYLEGS
>A0A538GY29|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MTIVQELTGIDTAVDRGAERLLSLQHPDGWWKGELESNATMIAQHLVLLHFLGLRDAETD
RLLANELLTRRRADGTWSIWFEGPADLSVTVEAYAALKLAGVDAGDATRQYIRRSGGVAR
TRIFTRAFLALIGQWPWRRLAHVPVELILLPANGPLSVYDFACWARQTMVALSVVEALQP
VRPSAIDLSEIGGRKTAGHGMPRLSERRRRAVAVAEHWVRERQEADGSWGGIQPPWVWSL
IMLAALGHGFEDETFARGLAGWQRFMVRDGDRLRPEACQSPIWDTALAVLALRAAGVPAD
DPRLQAAGSWLLGEEVTVRGDWAIRRPGLAPGGWSFEFDNDLYPDVDDTAVVALALRELD
LGDDAVRRGLDWMVGLQSRSGGWGAFDADNEALWLYRLPICDFGKVTDEPSADVTAHALE
AFGHEDGYGSSLASGLDWLLAEQETDGSWFGRWGVNHLYGTGAAVPALEACGLPADHPAI
RRALAWLDSVQQPSGAFGEDILSYRDAAARGRGAATPSQTAWALLAYISGGAAKGLSTRR
TAEYLCQSQRPDGDWDEQHYTGTGFPLDFMIRYHLYRLTFPLLALGRLRERLNG
>A0A7K2QJT6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID7760|TrEMBL
MTATTDGAGTPGVDPDITSPETAPGAQEAVARATRHLLARQDAAGWWKGDLETNVTMDAE
DLLLRQFLGIRDEATTQAAALFIRGEQGEDGTWATFHGGPPELSATIEAYVALRLAGDEP
DAPHMARASAWIRAHGGIAAARVFTRIWLALFGWWSWDHLPELPPELVFLPPWVPLNIYD
FGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDARRPYPVAERPAPLASWEGVFQRMDR
ALHVYRRFAPRLLRKAAMDTAARWIIERQENDGCWGGIQPPAVYSIIALHLLGYDLAHPV
MRAGLESLDRFAVWREDGARMIEACQSPVWDTCLAAIALADAGLAPDHPALVKAADWMLA
EEIVRPGDWAVRRPGLAPGGWAFEFHNDTYPDIDDTAEVVLALRRIKHPEPARVEAAIAR
GVSWNLGMQSRNGAWGAFDADNTSPLPNRLPFCDFGEVIDPPSADVTAHVVEMLAVEGKA
ADP
>A0A540Q5D4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces ipomoeae|TrEMBL
MTATTDGSTGAPPPRAASASDTDHDTPAAAGLQDAAAHAMRRATDFLLARQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDEKTTQAAALHIRGEQRADGTWATFHGGPPELSTTIEAY
VALRLAGDDPDEPHMARASAWIRQRGSIAASRVFTRIWLALFGWWKWDDLPEMPPELIYF
PKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPGRPNSPKSLDPLGSW
EGAFQRLDKVLHGYHKVALKRLRKAAMNSAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLRHPVMRAGLESFDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQL
VKAADWMLGEEIVRPGDWSIRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHPDP
ERVEKAVRRGTRWSLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIEWLLAEQEPNGSWFGRWGVNYVYGTGSVVPALVAAGLPASHP
AIRRAVAWLETVQNDDGGWGEDLRSYRDAAEWGGKGASTASQTAWALLALLAAGERDAKA
TERGIEWLAQTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYINGEPAVLK
ATGS
>A0A7V9CHV7|squalene-hopene cyclase|EC 5.4.99.17|Burkholderiales bacterium|TrEMBL
MWDRFTESLLPPSGNALADEPLSYVPAAPARRSARSTDYATSTPFIAELKHGIRDARRAL
LGLQKPDGHWCFELEADCTIPAEYILMMHFMDEIDAALERKIAVYLRARQSAAHDGWSLY
PGAAFDMSCSVKAYYALKLAGDDVDSAPMIRARAAILANGGAARCNVFTRIALALFEQVP
WRAAPLVPVEIMLLPRWFPFHPGKVSYWSRTVMIPLSILCSLKARAKNPRGISIAELFTI
PPEQENNYFPVRSALNRALLGIERIAFRFERFVPARVRARAIAKAEQWIIERLNGEDGLG
AIFPAMVNAYEALALLGYGPENLHRATAKRALEKLLVVGEESAYCQPCVSPVWDTALACL
ALQEADGDGKSASSPSRVKVRRALDWLTARQLDSEPGDWQHARPALRGGGWPFQYGNDHY
PDVDDTAAVGWAMQRAHDPRYAKPLQRAAQWVAGMQSKNGGFAAFDVDNTHYHLNEIPFA
DHGALLDPPSADVSARCIAFLGLNDAAFYADRISSAASYLCSEQESCGAWFGRWGTNYIY
GTWSVLTALEAAGVLFDSQAVASAVQWLKRVQRDDGGWGESNDSYLDDAVPGTHANSTAF
QTAWAMLALMAAGEAGSEAVARGAAYLLRAQRDDGLWRDDEFTAPGFPRVFYLKYHGYDK
YFPLWALARYRHLLPAEDRIAAGDKPALQAQTMLVDCS
>A0A6I4YWN0|squalene-hopene cyclase|EC 5.4.99.17|Saccharibacter sp. EH611|TrEMBL
MKESSVSETSFRQKLGATAIERAIEGSHAALGRRQNDDGHWVFELEADATIPAEYVLLEH
FLDRIDADRQQKIGVYLRRIQGDHGGWPLYQDGGFDISATVKAYFALKAIGDDPEALHMR
RARAAILQHGGAERSNVFTRIQLALFGEVPWDAVPVMPVELMLLPRKAFFSVWNMSYWSR
TVIAPLLVLSARKPKAINPKNVHVQELFKTPPAHVKDWIRGPYRSIWGRAFKGLDTLLRP
IVPHLPKATHEKAIKTAISFIEERLSAGGLGAIYPAMANVVMMYRTLGVPDDDPRVVQAW
QALQDLMVEKDGEIYCQPCVSPVWDTGLSGLAMMEAASGPKGTKTPETMKGLRKAAAWLR
ERQILDVKGDWAINAPSLRPGGWAFQYENDYYPDVDDTAVVGMLLQRIDPEENHEAIERA
REWIIGMQSSNGGWGAFDIDNDLEALNHIPFSDHGALLDPPTADVSARCVSFLAQLGHPE
DRPVIEKGLAYLRAEQETNGSWFGRWGTNYIYGTWSVLCALNIAGVPHDDAMVKRAVRWL
ESVQNPDGGWGEDCASYEGAEPGRYKESLPTQTAWATLALMAVGRRDTEAVEKGMAYLAQ
AQDEHGEWHEEPYNAVGFPKVFYLRYHGYKQFFPLTALSRYRNLGTSNSGRVEYGF
>A0A5D0TWU9|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura syzygii|TrEMBL
MTTTDVSGLTGAAAAAAEAARDHLLRLQSPEGWWKGELETNVTMDAEDLLLRQFLGIRSD
AETAEAARWIRSQQRPDGTWANFHGGPPDLSTTIEAYVALRLARDPVDADHMRRAAGYVR
ESGGIEAGRVFTRIWLALFGLWSWDDLPVMPPELMFLPNRFPLNVYDWGCWARQTIVPLT
VLGSLRPVRALPFDLPELRSGVRPAKDERGWGRFFTGLDRVLHVYQRRPVGPLRRAAVRR
AADWIIARQEADGCWGGIQPPWVYSLMALYELGYGLDHPVIKRGLDGLDRFTIRDERGRR
LEACQSPVWDTVLAINALGDAGVPPADPALRRAAAWVVDEEVRGLGDWAVRRPDVPPGGW
AFEFDNDVYPDTDDTAEAILALRKVDLPEAEQPIQRAIRWLEGMASRDGGYGAFDADNTR
ELCTKLPFCDFGAVIDPPSADVTAHVVEALAGEGRAESRTVKRAVVWLLKAQEADGSWFG
RWGANHVYGTGSVVPALVAAGVPAHKPPIRRAVEWLEAHQNPDGGWGEDLRSYEDPAWIG
RGESTASQTAWALLALLAAGERSHAVDAGVRWLVDHQRPDGTWDEDQFTGTGFPGDFYIN
YHLYRLVFPISALGRYLGGSR
>A0A7W8LHL5|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia sp. HC6.4b|TrEMBL
MNDLSHTQPLDAALPEAADAAPDLAEAAVVANAPAVADALATATPAPVQGANALDASITR
ATDAILAAQQPDGHWVYELEADATIPAEYVLLVHYLGETPNLELEQKIARYLRRIQLPSG
GWPLFTDGALDISASVKAYFALKMIGDPVDAEHMVRARDAILAHGGAEHANVFTRILLAL
FGVVSWRAVPMMPVEIMLLPVWFPFHLSKVSYWARTVIVPLLVLNAKRPLARNPRKVRID
ELFRGAPVNTGMNERAPHQHAGWFGLFRCVDSVLRAVDGLLPKATRERAIRAAVAFVDER
LNGEDGLGAIFPAMANSVMMYDVLGYPADHPHRAIARKSLDKLLVIKDDEAYCQPCLSPV
WDTSLAAHALLETGEARAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYNNA
HFPDVDDTAVVAMAMHRSAALTQSDVDREAIARAREWVVGMQSSDGGWGAFEPENTQYYL
NNIPFSDHGALLDPPTADVSGRCLSMFAQIGELPQSSEPARRAFDYMLQEQESDGSWYGR
WGLNYIYGTWTALCSLNAAGMPHDDPRMRRAVQWLVSIQNDDGGWGEGGESYKLDYRGYE
RAPSTASQTAWALLGLMAAGEVHHEAVARGIDYLQREQREHGLWDETRFTATGFPRVFYL
RYHGYRKFFPLWALARFRHLKRNGLTRVTVGM
>A0A5N9A6T4|squalene-hopene cyclase|EC 5.4.99.17|SAR202 cluster bacterium|TrEMBL
MVVEPKNMDVNQAADQAVGRSHDYFRRTQYPDGYWWGELESNATMEAEYLMLCHFTGRYD
EERWRKVCNYILSKQRDDGSWGQYYEAPGDLSTTTECYFALKLAGHSPDAEPLRKAREFI
LSKGGMPKVRVFTKIWFALFGQWDWKGTPNMPSEMIFLPSWAPFNIYEFASWARATVVPM
LIILTRQPHCPVPESANIDELYPDGRDGTDYSLPKPTDGLGWAKFLYWADKAVGLYQRLP
VHPFRGMAERRIMKWVLEHQEADGSWGGIQPPWVYSLIALHVMGYGPEHEAVKKGFQGFE
GFAIEDEEKCTVQACVSPVWDTCLAQLALMDSGIDPEDPMVQGSTRWLLDKQIFSGGDWQ
VRSKNQRPGGWSFEFANEKYPDIDDASIVVMALDPVRLPEAEEPRRADSIQRGVEWMAGM
QSKNGGWAAFDKDNNKKYLTKIPFSDFGETLDPPSVDVTAHLLEMYGRLGYTKDDQAVIR
GYNYVTGEQEEDGSWFGRWGVNYVYGTGAVLPALEAIGEDMSQPYIKRAVDWLLAHQNED
GGWGESCGSYVEPALRGVGPSTASQTAWALLGLVAAGEHGCEGVRRGVIYLAGTQQEDGA
WDEPYFTGTGFPGYGVGERLDALPNPGETSYLGLDMPAGFMINYHLYRNYWPLLALGRYS
RAVSAK
>A0A544V8D8|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus sp. SDF0028|TrEMBL
MSNVLRAVDDEIERLTKTLIEQQRQDGSWRFCFENGTSVDAYVIIIFRMLNVPNEELIRQ
LHNRILAAQQPDGCWRLFADEEEGNLSASVESYYALLYSGYSQAADEPIQRARRYILSKG
GLGKVSNIMTTAILAATGQRKWPASISSIPLEVVLFPTYFPINIYDFSGYSRVHLIPMLI
MGDKQFSMSSAHTPDLSDLYVRTMDEEDPLPRSFQEIQNMIKEGLKLLIGTPRYIHEAAT
TKAEQFMLERIEADGTLYSYANSTILMILALLALGYDQQHPLITRAIQGLTDMQFRYHGT
TTMQNSPSTVWDTALLAYTLQQAGIAADHLAIRRAAAYLLSKQQDKTADWSIHNPDTIPG
GWGFSETNTINPDVDDTTAALRAIRRLSNINSTYLESWNRGLNWALSMQNKDGGWPAFEK
NTNNDILTWLAIDGAKSAAIDPSEADLTGRTLEYLGNFARLDIRHEFIKRGTNWLVRHQE
KDGSWYGRWGVCYIYGTWAALTGLAAVGLPANHEPLQQGARWLMDIQNPDGGWGESCQSD
RLRHYVPLGESTPSQTAWALDALIAVHTQSTPEVDQGIHRLIALLHEDDWKSTYPTGAGL
PGYFYSHYHSYRYIWPLLTLSHYTKRYGNQ
>A0A7W6T1M9|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. SBR1B|TrEMBL
MDSVNATSREALQPGTLQPGILQSGILESSIASATQGVLDFQQADGHWVFELEADCTIPA
EYVLLRHYLAEPVDAVLEAKIANYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGD
PVDAPHMVRAREAIHARGGAIHSNVFTRFLLAMFGVVTWRAVPVLPIEIVLLPFWSPFHL
NKISYWARTTMVPLMVLAALKPLAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFVLF
RSLDAILRVIEPMFPKALRKRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKD
ENFPPRAITRRGIDKLLVIKDDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLD
WLIPKQELELKGDWAVKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGATGY
DAAIDRGREWIEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISML
AQLGETEKTSKHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDHGDPM
IRKAADWLASIQNKDGGWGEDAVSYRLDYRGWEAAPSTASQTAWALLALMAAGEVDHPAV
ARGVEYLIATQNKKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRV
VGVGM
>A0A6G9SDI5|squalene-hopene cyclase|EC 5.4.99.17|Tolypothrix sp. PCC 7910|TrEMBL
MQTQERATTNQVAEAIAKSQQYLLSIQNPAGYWWAELESNVTITAEAVLLHKIWGTDSTR
PLHKVENYLRSQQREHGGWELYFGDGGELSTTVEAYMALKLLGVSATDPAMLKAKAFILQ
RGGISKTRIFTKLHLALIGCYDWRGIPSLPPWIMLLPNSFPVNIYEMSSWARSSTVPLLI
VCDRKPIFQIDPAISVDELYVEGRDRVQWELPRSGDWTDIFITLDQGFKFAESLNLVPFR
KEGIKAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLDYDPADPIVERGLKAVDNFAIE
TADSYCVQPCVSPVWDTAWAIRALIDSGYAPNDSAIVKAGEWLIEKQILDYGDWTVKNRQ
GKPGAWAFEFDNRFYPDVDDSAVVVMALHQAKLPNEKLKQAAIARALNWIASMQCKPGGW
AAFDIDNDQDWLNSIPYGDLKAMIDPNTADVTARVLEMLGASNLSINQHNFDRAIAYLLE
EQEQEGCWFGRWGVNYIYGTSGVLSALALVAPKTQQQSIERGAAWLVGCQNPDGGWGETC
RTYNDPSLKGQGTSTASQTAWALIGLIAAGEATGKFAYNAIEQGINYLLTSQKPDGTWYE
SYFTGTGFPCHFYLKYHLYQQYFPLIALGRYRSVLGTGD
>A0A7S6S7U5|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MNGSQRIAAVSQQQDDFTVNDEAPESYTAPALNQDGINAAELETKFAQARAAMLALQNPD
GHWCFPLEADCTIPAEYILMMHFMDEIDVILENKIARFIRDKQDMTHGGWPLYYGGAFDI
SCTIKSYYALKLVGDSTDAPHMVRAREAILQRGGAAKANVFTRLLLAMYDQIPWRGVPVV
PSELVLLPSWFPFHISKVSYWSRTVMIPLSILCTMKARAINPRKVNIRELFIVPPEEEKN
YFPKADTLLKRAFMLVERILSRFEPKLPQSIRQYSIRKAERWTLERLNGECGIGAIFPAM
VNAHEALTLLGYDYDHPSRVQCRNALRGLLVDEGERSWCQPCTSPVWDTVLTSLALQEDP
TTGQEPVLKALDWLVDQQVLDEPGDWRDKRPDLLGGGWAFQYANPHYPDLDDTAAVAWAL
DQGGAERHQQSLERAANWLAGMQSRNGGFAAFDIDNVHHYLNEIPFADHGALIDPPTSDV
TARCVGLLGKYGKHQREVWRGISFLLREQEKNGSWFGRWGTNYIYGTWSVLEAFRLAKFD
MQHISVRRAVKWLESVQRVDGGWGETNDSYLDTQLAGRFTETSTAFQTAWAVLGLMAAGE
VHSEPVRRGIQYLLRNQCDDHLWEEPWFTAPGFPRVFYLRYHGYSKFFPLWALARYRVLT
REVGN
>A0A661F3Y6|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MFTENYNNMTNTRTIESAIKNAQDKLLSLQHKDGYWIFELEADCTIPAEYIMMMHYLDDI
DAELQAKLANYLRANQADDGSYPLFRGGAGDISCSVKVYYALKMAGDQPEQAHMTRLRDY
ILSQGGAAKANVFTRIALAIFEQLPWRGVPFIPVEIMLLPKWFPFHIDKVSYWSRTVMVP
LFILCTLEAKAKNPLNIDILELFITHPDKEQHYFAERGLLNKFFLFLDALGRKSRILITD
KMHRRAVDKALNWFTERLNGEDGLGGIFPAMVNAYEAMLLLDIPADDERVITARKAIDKL
LVIKENEAYCQPCLSPVWDTGLTLLALQEADLKNSKAQRKRAYDWLKTKQLSDEPGDWRI
QRPNLEGGGWAFQFENPYFPDVDDTAVIAFGMATSGLPDMDESIHRATRWIVGMQASNGG
YGAFDVDNTYYYLNEIPFADHGALLDPPTIDVSARCVMLMAKASQDHEEYLPAYHRCINY
IRSEQEEDGSWFGRWGTNYIYGTWSVLMALEHTNTPKSDPMYTKSTSWLKSVQHEDGGWG
EDNQSYDDDSLRGQFHTSTAFQTAWAILALMASGETDTKEVKSGISYLLNSQTEDGVWAD
ECHTAPGFPRVFYLKYHGYDKFFPLWALARYRNEQNKT
>A0A7X2PLZ5|squalene-hopene cyclase|EC 5.4.99.17|Bryobacterales bacterium|TrEMBL
MSAVFPTQQPFRRRSIVGELLEERQNLRDAARSAADLSARALVKKQTADGYWCGELLADI
SLESDYVLLELWLHPPEQGVWNPPSKRRLEKVCRRILSQQMADGGWWVYPDGPADINSTV
KAYTALRMCGHSPDSTPMRAACNRIHSLGGLQACNSYTKINLSLFGLYPRKYVPTIPPEL
VLVPGGSLYMGGMLYEMASWTRAIVVPLSIVQSVGGVRPAPEGISVDELILPGVRLGLPK
RDRFLSLLFHQVDKLLKLWERRGHRDARTAAIRQAERWMLDHCRNSDGLGAIYPAIQYTV
MALEALNYPSDHPDLIEAKAHFERLITETDEDLYFQPCFSPVWDTAYAAFSLAEAGYPNA
EALRKSADWLLAKEIRRRGDWAVKRPHLHPSGWAFEFNNEHYPDIDDTAMVLMCLEHSVA
SDPEKQRAVEARALDWLKGMQSRDGGYAAFDADNDWGVLNSIPFSDHNAMLDPTCPDITG
RVLEALARRGVPKSDPAIHGAVRYLVNRQEKNGSWYGRWGVNYLYGTFLALRGLRAAEYD
DPNLYRRATDWVVSVQNADGGWGESCLSYVRDEFVSAPSTPSQTAWALLTMHAAGRKESP
YAERGARYLIDTQSEDGSWPESLATGTGFPNVFYMRYTMYRHYFPLWVLGLYSQ
>A0A6L7QCS8|squalene-hopene cyclase|EC 5.4.99.17|Holophagales bacterium|TrEMBL
MAGLTRGLHDRPESSPTPPPKVIDLMIDAAVRNLLGQCRDDGHWCAELEGDTILESEYVL
LLHFLGRGDDPRVAACCGRLRSQQQQGGGWAIYPDGPTDPSVSVKAYLCLKLAGDDPQSP
RMADARRAILRAGGLRACNSYTRLYLSIFGLWTWRRSPAVPPELILLPRWFYFNLHEMSS
WTRTIVVPLSVIWALRPSVPLDVTLDELQGDSRPGRKRTTVYESFWSFVFAAVNGLIKLV
EVVGPVPGWRRPALKKAEEWLIAHVEGSDGLGAIFPAMLNTVIALRCLGYEESHPLVQGQ
LRELERLEIEEAGEMRLQPCLSPVWDTALSVGALLAADMEGGEAPIQDALAWLLEREVTV
PGDWREKSLQEAPGGWCFEYRNDLYPDCDDTAEVLVLLASVRGRTDELEARRQAATARGQ
RWLLGLQNPDGGWASFDRCCDKEVLTLIPFADHNAMIDPSTPDITARVISALLAHGHDPR
DEPVRRATDYLLREQERDGSWPGRWGANGIYGTWLALSALAPLAARPGIRAGERLSRACR
RGRRWLLAVQNEDGGWGESLRSYDDPDFRGRGRSTASQTAWAMMGLIVSLEPRPWSDDAA
RTVAALDRAVAFLQERQRDDGSWYDRDWTGVGFPGVFYLRYHGYAQYFPLEALAAYRRLA
VPEPDAMPANGPF
>A0A166RBV8|squalene-hopene cyclase|EC 5.4.99.17|Frankia sp. EI5c|TrEMBL
MVISATPETVEHTVPEQAGSSAAAGRGRPGPAGRGHEDPLARALRRAADQLLSRQDAAGW
WKFDLESNTTMDAEDLLLREFLGIRTASVTAASALFIRGRQLPDGSWPQYFQGPGDLSVT
VESYIALRLAGDEISAPHLERAAAWIRRNGGIPATRVFTRIWLALFGWWRWEDLPVLPPE
IMLLPARAPLSIYSFGSWARQTIVPLTVVFALRPVRPAPFDLAELSVAGEASKRPASGEN
GTGAGARRRRGPVRIGWKEVFRRVDAGLHRYHHHPIGPLRRHALRVAEQWIIARQEADGC
FGGIQPPAVYSIIALHLLGYDLAHPVLKAAFAALDAYTVALPDGSRMVEASQSPVWDTAL
AVNALVEAGAVTGTEPDDPALVRAADWLLGQEIRDRRGDWRVNHPDLPAGGWAFEFENDT
YPDTDDTAEVLLALRHVRHPDPAQIDAATARTVTWLFGLQSRDGGWGAYDSDNTSTLVYE
IPFGDFGALTDPPSADVTAHVVEILAEAGFAQDARTRRGVAWLLRHQEADGSWYGRWGVN
HIYGTGSVLPALVAAGVEPTHPAVRRAADWLLSRQNVDGGWGEDLRSYSDPRWRGQGAST
ASQTAWAMLGLLAAGPRPEVAAALARAAHWLADHQRPDGSWDEDQFTGTGFPGDFYLNYH
GYRLIWPVLALGRYLRTNPSRSRSVPARDA
>A0A8F6C8E4|squalene-hopene cyclase|EC 5.4.99.17|Methylococcus sp. Mc7|TrEMBL
MLREATVISNLEPPLTASYVESPLDAAIRQAKDRLLSLQHLEGYWVFELEADCTIPAEYV
LMMHFMDEIDGELQAKIANYLRAHQSADGSYPLFQGGAGDISCTVKAYYALKLAGDSVEA
PHMKKAREWILAQGGAARSNVFTRIMLAMFEQIPWRGVPFIPVEIMLLPKWFPFHLDKVS
YWSRTVMVPLFILCSHKVTARNPSRTHIRELFTVDPQQERHYFDHVKTPLGKAILALERF
GRMLEPLIPDAMRKKATQKAFEWFTARLNGVDGLGAIFPAMVNAYEALDFLGVPPDDERR
RVARESIERLLVFQGESAYCQPCVSPIWDTALTSLTLQEVARHTADIQLDAALHKGLKWL
ASKQIAKDAPGDWRVNRPGLEGGGWAFQFGNDYYPDVDDSAVVAHALQGSEDPSFDETLR
LAANWIAGMQSSNGGFGAFDADNTYYYLNSIPFADHGALLDPPTADVSARCAMFLAKWVN
RQPELRPVLERTIEYLRREQEADGSWFGRWGTNYIYGTWSVLLAYEAAGIPNDDPSVRRA
VAWLKSVQREDGGWGEDNFSYHDTSHRGRFHTSTAFQTGFALIALMAAGEAGSPEVQAGV
DYLLRQQRPDGFWNDECFTAPGFPRVFYLKYHGYDKFFPLWALARYRNERYARA
>A0A066PR96|squalene-hopene cyclase|EC 5.4.99.17|Acidiphilium sp. JA12-A1|TrEMBL
MFDTISFDFDALDQAISRAHARLSAEQRADGHYVYELEADATIPAEYVLLEHFLDRIDPE
LEARIGVFLRGIQGNSPQNPGGWPLFHDGAMDISASVKAYFALKAIGDDPDAPHMRRARE
AILARGGAARTNVFTRIQLALFGAVPWRACPVMPVEIMLLPDWFPITIWKISYWSRTVIA
PLLVLLTERPIARNPRNVRIDELFVTPPDQVTDYIRGPYRSNWGYLFKAIDSALRPLERH
FPARSRKRAIQAAIDFITPRLNGEDGLGAIYPAMANTVMMYHTLGYSPDHPDYATAWASV
RKLVTDASYRFEGASYVQPCLSPVWDTSLAAHALAEAGSPGDAQLAAACDWLIPRQILDV
KGDWAYRKPDAPPGGWAFQYNNAHYPDVDDTAVVGMILDRNGDPAHREAVERARQWILGM
QSRSGGWGAFDSDNEFHYLNHIPFADHGALLDPPTADVTARCISFLAQLGHAEDRPAIER
GVAYLRREQEQDGSWFGRWGTNYIYGTWSSLCALNAAGVAQDDPMMVRAVEWLLARQRPD
GGWGEDCETYAHAKPGEYHESLPSQTAWALLGLMAAGQAEHEAVARGIAWLQSVQEDDGS
WTEQPYNAVGFPRVFYLRYHGYPRFFPLLAMARYRNLARGNSRQVQFGF
>A0A7W7RAU6|squalene-hopene cyclase|EC 5.4.99.17|Kitasatospora kifunensis|TrEMBL
MRLPIRSGERGDARVGAAVGRATEHLLGLQSPDGWWKGEQSTNITMDSQDLLMREFLGIR
TAQESAESARWIRSQQREDGSWAVFDGGPGELSTTVEGYIALRLAGHRADEPHLLRAADW
VRRHGGLQGSRVFTRIWMAMFGLWPWNGLPVLPPELVLLPPGVPLNIYDWACWARQSIVP
LSVIGHFRPVHPLPFDVDELRSPQAGPAVPQPRGPLEVCLRRLDQVLRLWDGAAARRSGP
LRRRALRRAADWIVERQEADGSWGGLQPPWVYSIIALHLLGHPLDHPIIRRSLDGFDGFL
IREETPEGTVRRLEGCQGPVWDTALAVIALTDAGLAPDHPALTSAAHWLLGQELRSTGDW
SVRRPRLAPGGWAFGFTNAHYPDLDDTAEVVMALERLRTPTAPSATAIGEAVDRGVAWAV
GMQSKDGGWGAFDADNTRALVEKLPFCDFGRLIDPPSADVTAHVVEMLAAQGLTRTPATG
RAVRWLLERQEEDGSWFGRWGVNHLYGTGAVLPALAAVGIPSAHPAVQRAVQWLHAHQNT
DGGWGEDPRSYLDPHWIGHGPSTPSQTAWALLALLAVGDTSATVDRGIAWLLATQRADGG
WDEPQFTGTGFPGDFYIRYHLYRDVFPLTALARHLARAQNGCTS
>A0A522WS96|squalene-hopene cyclase|EC 5.4.99.17|Methylobacter sp|TrEMBL
MFNEANSEINFSTIPCSSNTVNNHTFDLNRAIDKAQEKLLSLQDKDGYWVFELEADCSIP
SEYIMMMHYLGEIDQPLQAKIANYLRSRQSEDGSYPLFTGGVGDISCSVKVYFALKMAGD
SIDAPHMIRLRSYILSQGGAAKANVFTRIALATFKQLPWRGVPYIPVEIMLFPSWFPFHL
DKVSYWSRTVMVPLFILCTLKATAKNPNNINILELFVTHPDEEKHYFPERTLLNKIFLGL
DKLGLATRPLIPKKAHELAIAKAKDWFIERLNGEDGLGGIFPAMVGSYEAMLLLGMPKDH
PHVVTARKAIDKLLVINEHDAYCQPCLSPVWDTALTALALQEADKAGNSQSLTRAYDWLK
SKQLSDEPGDWRISKPDLAGGGWAFQFENPHYPDVDDTAVVAFAMAESNLPHLDESIHRA
TRWVVGMQSKNGGYGAFDVDNTYYYLNEIPFADHGALLDPPTTDVSARCAMLMARVAQDH
AEYVPALERTIDYIRSEQEQDGSWFGRWGTNYIYGTWSALLGLEQTNLPKNDPMYTKAAT
WLKSIQRGDGGWGEDNYSYHDLSHSGKYRFSTAFQTAWAVLALMAAGEAHSHEVKAGIAF
LLRNQQADGVWNDECFTAPGFPKVFYLKYHGYDKFFPLWALARYRNELSSK
>A0A4S5ERF3|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Frankia alpina|TrEMBL
MPDLELCDVDLADGTQHAPNTGRTATLPQQAHAHERTTATASSAAADEPIPGLRETVRRA
AEHLLSLQDSHGWWKFDLETNPTMDAEDLLLREFLGIRTAEQSEAAAKYIRSRRLDDGSW
PTFFGGPGELSTTVESYIALRLAGDSPDDESMRRSAAWIRERGGIPATRVFTRIWLALFG
WWRWEELPVLPPEIMFLPPKAPLNIYSFASWARQTIVPLTVVSAKRPQLPAPFDLDELRT
AVVPVAPAGNPRGLRASLRLLGRDRPSAAKTFFLRLDAALHRYHRHPIGPLRRHALRTAE
RWIIARQEADGCFGGIQPPAVYSVIALRLLGYDLDHPVLAAALRSLDAYAVHREDGSRMI
EACQSPIWDTALAVLALADAGLDAEADAPSTPSTLPTPRAASDDAPAQPAAPAAPAAPAA
PATALGLAADYLLGQEVTHRGGDWAIIHPTVTPSGWAFEFENDAYPDTDDTAEVVLALHR
VHRLKPLSPAADEAVKAAVERSTTWLFALQSRDGGWGAYDSDNASTLVYQIPFADFGALT
DPSSADVTAHVVELLCETGRIRDPRTLRGVDWLLRNQETDGSWYGRWGVNYVYGTGSVLP
ALQAAGLPPTHPAMRAGAQWLLSRQNSDGGWGEDVRSYSDPAWSGRGTSTPSQTAWAMLG
LLATDHAGVHGSVPRGVHADALAGAARWLTEQQRPDGGWDEELFTGTGFPGYFYLNYHGY
RLLWPVMALGRYLHTRQDPSS
>A0A6G4B6L2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces harenosi|TrEMBL
MTATTDGSTGATLPPRAAAASETDSTVPAAAGVPEAAARAMRRATDFLLARQDAEGWWKG
DLETNVTMDAEDLMLRQFLGILDEDTTRAAALFVRGEQREDGTWATFHGGPGDLSATIEA
YVALRLAGDAPDAPHMARASAWIREQGGIAASRVFTRIWLALFGWWKWEDLPELPPEIIY
FPTWLPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPARPNPRRPLAPAAS
WEGAFQRIDKALHAFRKVAPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSIIALY
LLGYDLQHPVMRAGLESLDRFAVRREDGARMIEACQSPVWDTCLATIALADAGLPADHPQ
LVKAADWMLGEQVVRPGDWSVRRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHHD
PERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGLAHDPRTRRGIQWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALVAAGLPGSH
PAIRRAVAWLESVQNDDGGWGEDLRSYRDAAQWSGRGASTASQTAWALMALLAAGERDSH
AVERGVRWLATTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPAVL
TAPAAGRPLAEAKVS
>A0A6P0ILC2|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO3I7|TrEMBL
MQTQDRIVNSGVTEAIANSQSYLLAQQYPDGYWWAELESNVTITAEIILLHKIWGTDKQR
PLHKAEAYLRSQQRKHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDSALVRARDFILR
RGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPEWFPFTIYEMSSWARGSTVPLLI
VFDQKPVFDIQPRINLDELYTEGADHAKFELPRNSDWTDLFVLLDDGFKLAEDLNLVPFR
KQGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPVVQRGLEAIDRFAIE
TPDSYRVQACVSPVWDTAWVLRAMVESGLEPDHPALVRGGEWLLQQQILDYGDWVVKNPQ
GKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLKQAAIARGLAWIASMQCNQGGW
AAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEMLGSCNLSIESQQLEKAIAFLIQ
EQEADGSWFGRWGVNYIYGTSSALSALSKIAPHTHQRSIERGAAWLVKCQNLNGGWGETC
LSYDDPSLKGLGISTASQTAWALIGLMAAGEATGNWARDAIERGVNYLVSTQQPDGSWDE
TEFTGTGFPSHFYLKYHFYQQYFP
>A0A3M8DK33|squalene-hopene cyclase|EC 5.4.99.17|Brevibacillus fluminis|TrEMBL
MNNNVEPEISRLIAYFQQNQATDGSWRFCLENSPLTDAYMIILLRTLDVPDEQSIARLAA
RIASMQQPDGCWRLFPDETAGNLSITVESYYALLYAGYYQKTDPAMRAAFQYIRQNGGLS
KTSMLTKVMLALTGQYPWPAASPPIELLLLPRFSPISFYDFVGYARVYLTPILIAADRKA
SFPTAHTPSMVDLYVDNGTDTDSLLGFFDTIRQGVKQLPFLPAQLHALALRKAERFMLAR
IEPDGTLYSYFGATFLMIFALMALGYRRDHPVITRAVTGLYGLFCQANGQLMMQNNTSTV
WDTALASHALLNAGLPANDPMMRKSADYLLARQQQKASDWSWNNPGVAPGGWGFSDINTL
NPDVDDTTTSLRAMRRMMQVDRRYRSAWDRGLTWILSMQNDDGGWPAFEKNTDKAIMRSL
PIEGAAAAATDPSTADLTGRTLEFLGNDTGFTLASPAIGRPVSWLLRQQEKDGSWYGRWG
ITYLYGTWAALTGMCAVGLPADHPAVQKAVAWLTRVQNADGGWGESCKSDVLKTYVPLGI
STLSQTAWATDALIAASPKSTPAIERGIRFLIQSGTKSDWTTNYPTGAGLPGGFYFQYDS
YQKIWPLLALGNYRNKYA
>A0A8J7WP45|squalene-hopene cyclase|EC 5.4.99.17|Actinocrinis puniceicyclus|TrEMBL
MTAIADRPVAAGTEPGPLEAARRAAERARDHLLALQDPAGWWKGELATNVTMDAEDLLLR
EFLGIRSARETEAAARWIRSQQRQDGTWATFHGGPAELSTTVEAYIALKLAGDAPDAPHM
KLAVEWIQAQGGVERTRVFTRIWLALFGLWDWERLPVMPPELIFLPPQVPLNIYDWGCWA
RQTVVPLTVVSHFRPSRPLPFGIDELRTGAGEPPLSPAATTAGFFQRADRLLHRYELLRR
KPMRKAALKRAAEWIVARQEADGGWGGIQPPWVYSIMALHLMGFSLDHPVIRAGLEGLEG
FLVREQTPDGPVRRLEACQSPVWDTALAVVALTDAGVAGGDPAIVKAADWLLDEEITVRG
DWAVRRPGLAPGGWAFEFANDGYPDTDDTAEVIIALHRAAQGADEGRAAALDGAIERGMR
WMAGMQSRDGGWGAFDADNTRELVNKLPFCDFGAVIDPPSADVTAHIVEALAIRGRARDP
RVRRGVRWLLEHQEADGSWFGRWGANHVYGTGAAVPALIEAGVARDHPAVRRAAAWLIGH
QNPDGGWGEDLRSYVERAWIGRGESTASQTAWALLALLAAQEPGEHPRSAAARAAADRGI
EYLARTQREDGTWDEDLFTGTGFPGDFYINYHLYRLVFPLTALGRYLAERLVESP
>A0A7X3HNK7|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus sp. SW-Y-13|TrEMBL
MNQAATITISRNDAQRASQRRAAPSTLPDPLDDSIAHAVDALLAQQQADGHWVYELEADA
TIPAEYILMVHYLGETPDLVLEGKIANYLRRIQGTDGGWPLFHAGAPDVSASVKAYFALK
MAGDDPEAAHMRRARAAIHAMGGAEASNVFTRTLLALYGVMPWQAVPMMPVEIMLLPEWF
PFHLSKVSYWARTVVVPLLVLNSLRPKARNPRKIGIDELFLRPAQATRLPARAPHQSPLW
VTVFRALDAVVRVAEPLFPRRMRQRAIERARAFTVERLNGEEGLGAIFPAMVNSVMMFDV
LGVPANDPDRAIARKSIDKLLVIRDDEAYCQPCLSPVWDTSLASHALLEVGEPRTIAAAS
RGLDWLVPLQELELRGDWTVRRPDVRPGGWAFQYANPHYPDVDDTAVVAAAMDRADRGDC
SNRYTPAIARACEWVIGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDPPTTDVSARC
LAMLCQLGQMPANSEAAARALRYVLDEQEADGSWFGRWGTNYIYGTWSALCGLNAAGIGA
DAPEMQRAAQWLASIQNEDGGWGESGDSYKLDYRGYEKAPSTASQTAWAMLGMMAAGAGH
HPCVARGVEYLLRTQASHGFWDEPYFTAVGFPRVFYLRYHGYARFFPLWALARFRNLLRD
GNHAVAWGL
>A0A3N0WA94|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa FACHB-524|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
KRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVDDPIVARGLKAVDNFAIQ
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPSIIKAGQWLIDQQILDYGDWAIKNKI
GPPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKSVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVKMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYQALI
>A0A4S3G7T5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. Akac8|TrEMBL
MTATTDGSTGAASPSRLTAASEHDTDSPEAAGVPDIAARAVRRATDFLLSRQSDEGWWKG
DLETNVTMDAEDLLLRQFLGILDEDTTRAAALFIRGEQREDGTWASFYGGPGELSTTIEA
YVALRLAGDAPDAEHMAKASAWIREQGGIAASRVFTRIWLALFGWWKWEDLPELPPELIW
FPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPANPSPPRPLAPANT
WDGAFQRLDKGLHALRKAVPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLNHPVVRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHPQ
LVKAADWMLGEQVVRPGDWSVRRPHLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHHD
PERLDNAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGLAQDPRTRRGVEWLLAEQEPDGSWFGRWGVNYLYGTGSVVPALTAAGIPTSH
PAIRRAVAWLEKVQNEDGGWGEDLRSYRHAREWSGKGASTASQTAWALMALLAAGERDSE
AVARGVAWLANTQKEDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFTA
KPAEATAAAGSAQALADAKGS
>I4ICP9|squalene-hopene cyclase|EC 5.4.99.17|Microcystis sp. T1-4|TrEMBL
MQIQEKISEIAAQTAKAIELSQNYLLSTQHPQGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPAIEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLEELYTEGVNNVKYELPKNNNWSDVFLWLDGLFKWAEKTNLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALDYDVDDPIVARGLKAVDNFGIE
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDEKIKKSVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVKMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNQYRQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A3G8H500|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus pauculus|TrEMBL
MTPQDIPASDLDAALERARDALLDLQQPDGHWCFELESDATITAEYILMMHFVDEIDTAL
QARMARYLRALQRRDRHGAWDLYYGGDVDVSCSVKAYFALKAAGDSPDAPHMVQARDAIL
AHGGAAKSNVFTRILLATFGEVPWRATPFMPVEFVLFPRWAPIHMDKVAYWARTTMVPLL
VLCSMRARARNPLGIHVQELFVTPPDLETEYFPRKRGLQGLFLKLDRVVRHVEPLIPRAL
RRKAIERAVRWSEERMNGEDGFGGIFPPMVYAYEMMVLMGYAKDHPMRRDCMDALKKLVV
HRDDGVSYCQPCLSPVWDTAWSLMALEQAPASPRSAEAVARGYDWMTARQVLDLTGDWQH
NAAPGTRPGGWAFQYENPYYPDIDDTAVVLAMLHAHGQRTGQAERFQPHVDRALDWSIGL
QSKNGGFGAFDADCDRDYLNAIPFADHGALLDPPTEDVSGRMLLAMGVTRRPQDATARDR
CIGYLRDTQQPDGSWWGRWGTNYIYGTWSVLAGLALAGVDRKLPMVRKAVDWLRGKQLAD
GGWGETNDSYLHPELAGTHAAGSTAEHTAWALLGQLALGEHESDSVKRGVAWLVRNQGDD
GFWTHPFHNAPGFPRIFHLKYHGYTAYFPLWALGRYRRLAGRRPAEATRPATVPERELA
>A0A7K0JTG4|squalene-hopene cyclase|EC 5.4.99.17|Acidiferrimicrobium australe|TrEMBL
MTAVPSTETWSDLLEAATAARDRARDHLLAAQRPEGWWKGELETNVTMDAEDLLLRHFLG
ILRPGLAARAARWIRRQQRPDGTWGTFHGAPPDVSATVEAYVALRLAGDEPHEPHMEAAA
AWVRLQGGLAATRVFTRIWLAMVGAWSWDDLPVMPPELIFLPPDAPISIYRFGCWARQTI
VALTVVMSHRPARPLPFGLDELRRPPGDTPADLAARTVEAPRHKVIRYDPVAGPAFSAID
RLLHSWERLPRWFLPKTLLRRAALSTAERWIVRRQEADGCWGGIQPPIVYSVIALHLQGY
ALDHPVLAAALAGIDGFVLEDQTGRRLEACQSPVWDTALSVIALADAGVPADHPAMRRAR
AWLVGEEIRVRGDWAVRRPELEPGGWAFEFANDLYPDIDDTAEVILALRRAGVAPGDPDD
DACRRGTAWTVGMRSRDGGWGAFDVDNDSELVKAIPFCDFGEVTDPPSADVTAHVLEMLA
AEPGVDPAVIDGAVRWLSDQQEPDGSWFGRWGVNYVYGLGAVVPALVAAGVPADDPRIRR
AVDWLVEHRNPDGGWGEDLRSYLDPAWRGRGASTASQTAWALLALLAAGEIGDGPGGDAL
RDGVEWLVEHLTEDGTWDEPWFTGTGFPWDFSINYHLYRHVFPLTALGRYVATMRARA
>A0A853CI09|squalene-hopene cyclase|EC 5.4.99.17|Geodermatophilus daqingensis|TrEMBL
MTLVRDPARPAAQDTAEAALARAVDHLRALQDDAGWWKGELETNVTMDAEDLLLRHFLGI
LTGAEAAEAARWIRSQQRDDGSWATFRGGPPDVSTTVEAWVALRLAGDDPAAPHMARAAA
VVRELGGVERSRVFTRIWLALVGLWSWSELPVMPPEMVLLPSWLPLNIYDWGCWARQTVV
PLTVVCTHQPVRPVDFDIDELRTGAAAVPRAPLRTWSGFFQRLDRGLARYAKHPLRRVRR
RAIAKAVEWIVTRQEADGGWGGIQPPWVYSLIALHLEGYALDHPVMRAGLAGLEGFLVRE
ETPDGVVRRLEACQSPVWDTGLALTALLDAGVPIDDAGVVRATDWLLGEEITVRGDWAVR
RPDLAPGGWAFEFANDGYPDTDDTAEIVLALRRVAHPDCARLRGAVDRGVSWTRGMQCRD
GGWAAFDADNTGSMPLKLPFCDFGAVTDPPSADVTAHVVEMLAAEGFAADEDCRRGVAWL
LEHQEADGSWFGRWGANHVYGTGAAVPALIAAGLPPSDPVIRRAVAWLERTQQEDGGWGE
DLRSYRDRAWIGRGEPTASQTAWALLALHAAGERGPAVQRGVRWLVEHQRPDGTWDEPQF
TGTGFPGDFYINYHLYRLVWPISALGRLVREGVGDGAEEGAA
>A0A7H8KPZ9|squalene-hopene cyclase|EC 5.4.99.17|Kitasatospora sp. NA04385|TrEMBL
MTATAGGRLGPQTSVAVTRSDDSSPVAALSRATAHLLSLQHADGWWKGDLETNVTMDAED
LLLREFLGIRTEEQTRATAAWIRSRQREDGTWTTFHGGPPELSTTVEAYVALRLAGDAAD
APHMRAAAAFVRERGGIAASRVFTRIWLALFGWWPWEELPELPPEVLFLPSWAPLNIYSF
GQWARQTIVPLTVVSAHRPVRPAPFGLAELHTDPADPYPRRPLAPAHSWDGLFQRLDQLM
HRYRRHAIKPLRRLALRQAAAWIVERQEADGCWGGIQPPAVYSLIALRLLGYRLDHPVMK
AGLAAFDSFTVHTEDGKRWLEACQSPVWDTCLAAIALRDAGLPGDHPALVRAGDWMLGEE
ITTRGDWAVKRPRLAPGGWAFEFQNDTYPDVDDTAEVVLALRRIDHPDRERLAGAVERAV
DWNLGMQSKDGAWGAFDADNTSKLPNRLPFCDFGEVIDPPSADVTAHVVEMLAETGRIRD
PRTRRGVVWLLRHQEADGSWFGRWGTNYIYGTGSVVPALIAAGVSRNHSSVRRAVAWLAD
RQNPDGGWGEDMRSYEDPATWAGRGESTASQTAWALMALLAAGERDSAAVERGIGWLTAT
QRPDGTWDEPQFTGTGFPWDFSINYHLYRLVFPVTALGRYVQDAPLGQGGGR
>A0A062X5L8|squalene-hopene cyclase|EC 5.4.99.17|Frankia sp. BMG5.23|TrEMBL
MSLTSDPSPAAPKAAKSSKRVNIPAPATPDAYGISRSSPPLSGGGVSGGGVSGGGVSGGG
AATADGTPPTTQTSVDPDLAAAMTAANQARDHLLGLQSEEGWWKGDLETNVTIDAEHLFM
KQFLGIRTEEETEPIARWVRSQQLADGGWATYYGGPAELSTTVEAYIALRLAGDEPDAPH
MAAAAALIRSQGGVAAARVFTRIWLATFGEWSWDDVPVLPPELIFLPSWFPLNVYDFGCW
ARQTIVALTIVGSLRPVRDLGFSIDEIKVAAPVTPPKPAPLHSWEGAFERLDAILHRYER
RPIKVLRTLALRRATEWVVARQEADGCWGGIQPPWIYSVMALHLMGYPLNHPVIATAFRG
MERYIIRRETPEGPTAQIEACQSPVWDTALAVVALSDAGVPADHPAMVRAGRWLVDEEVR
VAGDWAVRRPALAPGGWAFEFDNDFYPDTDDTAEVVLALRRLLGGSHVTPGGTVTPSGSV
TPGGTAELSPAARDRASRGLAAVDPQLAGAMRAAAARGVDWSVGMRSSDGAWGAFDADNV
RTLTAKIPFCDFGEVVDPPSADVTAHIVEMLADLGRSDHPITRRAVQWLLDNQEPGGSWF
GRWGINHVYGTGAVVPALIAAGVPADHPAITAAVRWLLEHQSPDGGWGEDPRSYDDPAWI
GRGELTASQTAWALLALLAVDPHSKAVKRGVRWLCETQRPDGTWDEPQFTGTGFPGDFYL
NYHLYRLVFPLTALGRYVTLTGVATP
>A0A6G7PF47|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. JB150|TrEMBL
MTATTDGSTGAALPARAAAASDTDTIPEAAGVHEAAVRATLRATDFLLARQDAEGWWKGD
LETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELSTTIEAY
VALRLAGDAPDAPHMAKASAWIRAQGGIAAARVFTRIWLALFGWWKWEDLPELPPELIWF
PSWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPARPNPPRPLAPAASW
DGAFQRLDKGLHAVRRVLPKRLRKAAMHTAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLQHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALVDAGLPADHPQL
VKAADWMLGEEIVRRGDWAVRRPELPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPQP
DLVDRAIGRGVRWNLGMQSKNGAWGAFDVDNTSPLPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIDWLLAEQEPDGSWFGRWGVNYIYGTGSVVPALVAAGLPTAHP
AIRRAVTWLQQVQNDDGGWGEDLRSYKYAKEWRGRGASTASQTAWALMALLAAGERESPA
VERGIAWLVATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGEPFSGK
QPRKPLAEAKGS
>A0A7C2X7J2|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MYENGAEPANATRGNFEAQLDASIKAAADWLKANQKPEGYWVGRLESNACMEAQWILCLW
FLGLEDHHLRPRLAASLRKTQRADGSWEIYHDAPAGDINTTVEAYAALRSCGVPANDPQL
LRARDWILSKGGLKNVRVFTRYWLALIGEWPWEKTPNIPPEVIHFPNWFIFSIYNFAQWA
RATLMPIAVLSARRPSRPLPPENRLDDLFPGGRANFDYELPGKPGADFWDRFFRTVDVVL
HKMQTFGVRTTLSFGRNGSVKRALEWIIAHQDADGVWGGIQPPWIYSTMALFNEGYAVDH
PVVAKSLAALDDPRWRVDRGDATWIQASTSPVWDTILTLLAFDDCHLNGEYPAAIEKALQ
WVLDQQVLRKGDWSVKLPNLEPGGWAFEYKNYFYPDTDDTAVALIALSRFAGDAKWKAKG
IDRAIQRGLNWLIGMQCENGGWGAFDKDNDKKFLTKIPFCDFGEALDPPSVDVTAHVVEA
FGKLGLGLNHPSMARAIDYLKREQEQDGSWFGRWGVNYIYGTGAVLPALAAIGEDMTKPY
VMRAADWLLTRQQENGGWGESCGSYMDPKLSGRGKATASQTAWALMGLIAVNRPADRDAI
ERGIAFLIERQKGGTWEEAEYTGTGFPGYGVGATIKLGDPLLTERLKQGPELSRAFMINY
NLYRHYFPLMAMGRWRNARA
>A0A537PLC5|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MNCVQPKSSAVDQSIEAATRGLFALQQPDGHWVFELEADATIPAEYILLRHYLAEPVDNM
LEAKIAAYLRRVQGEHGGWPLFHEGAFDMSASVKAYFALKMIGDSVDAPHMARARAAIRA
RGGASRSNVFTRVMLALFGFIGWRAVPVMPVEIMLLPKWFPFHLEKVSYWSRTVIVPLLV
LMALQPRARNPRRVALDELFLELPQTIGLAPKAPQQKAAWFWVFRAVDTVLRFAAPRFPR
PLRQRAMQCAVSWVTERLNGEHGLGAIFPAMANSVMMFDALGYADGHPHRAIARRSIEKL
LALRDHEAYCQPCVSPVWDTALACHSLLEVGSDQAVTQVRKGLEWLAAKQILELKGDWIA
RRPDVRPGGWAFQYANPHYPDVDDTAVVVMAMDRAQRLSSQNDFRASIAAAHEWILGMQS
NNGAWGAFDADNEHYYLNNIPFADHGALLDPPTEDVTARCISMLAQIDESAPNSAAVARA
VDYLRRTQTAEGSWYGRWGMNYIYGTWSVLCALNAAGVDHASPELRRAAAWLVKIQNSDG
GWGEDGMSYRLDYRGHESAPSTASQTAWALLGLMAAGENDHPAVARGIDYLLRTQGEDSF
WNEPRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLKNTNARSVPHGI
>A0A552AD79|squalene-hopene cyclase|EC 5.4.99.17|Microcystis sp. M_OC_Ca_00000000_C217Col|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKSATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPANDPTLEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWLGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEVVNNVKYELPKSNNWSDVFLWLDGLFKWAEKTNLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALDYDVDDPIVARGLKAVDNFGIE
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKAVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGVLSALAFLEPNKYRQQLQKGANWLSGCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWNE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A7V6DPM1|squalene-hopene cyclase|EC 5.4.99.17|Desulfobacca acetoxidans|TrEMBL
MPNVTATVFRDRIRTRPPAKTFLEKVKKARDQAVDALLALQHPEGYWWAELESNVTITAE
YLMMHRFLGLPGDKFPALVREILSQQLDNGGWSLWYEDGGDLSTSVEAYQALKMAGLSAA
DPRLVKARQFILERGGALASRVFTRINLALFGQVSWDGIPLLPVEFMLLPVWSGFSIYEF
SSWSRATMIPLSIVMAHRPVYPLPPSQGVAEIFAHPDDPFKHHQVAWKKQGPALENFFVL
VDRLLKLYARLPWALLRHLAMHKAERWILDHQEETGDWGGIQPAMVNSLLALACQGYKVS
HPVIQRGLAALEAFTLKLGDRLRLQSCISPVWDTGLAVRALAAAGLRPGHPALEKATAWL
LANQIFKPGDWSVKRPHLAPGGWAFEFDNNWYPDIDDSAVVLMALKEALTDPSPHQTALA
TGIAWCLGMQSKNGGFAAFDVDNTKDWLNAIPFSDLKALIDPPTEDVTGRVLEMMGTFGF
PKSHPAAVRALAIIRKWQQPDGCWWGRWGVNYLYGTWSVLLGLKAIGISSRSPMVRRAAT
WLSKCQNQDGGWGECCESYRDPTLRGQGPSTASQTAWAVMGLMAAGETASPAVKAGIDYL
VKTQQKDGRWQEQYFTGTGFPSHFMIRYHLYRDVFPLMALGMYLREFAGDTLQ
>A0A6G3BVM1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5643|TrEMBL
MTATTDGSTGALPPRAAAASDTDTHTPGAAGVPEAAARAARRATDFLLSLQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDEKTTRAAALFIRGEQGEDGTWATFFGGPGDLSATIEAY
VALRLAGDAPDAPHMAKASAWIRARGGIAAARVFTRIWLALFGWWKWEDLPELPPELVLF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPDRPSPPKPLAPLFSW
DGAFQRMDKGLHALRKVAPRRLRTAAMNSAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLEHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLAAIALVDAGLPPDHPQL
VKAADWMLGEEIVRPGDWSVQRPGLPPGGWAFEFHNDNYPDIDDTAEVILALRRIAHHDP
ERLDRAVVRGMRWTLGMQSKNGAWAAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIEWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALTAAGLPAAHP
AIRRAVAWLESVQNDDGGWGEDLRSYQDARQWSGRGASTASQTAWALMALLAAGERDSKA
VERGVEWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFAGR
LKGS
>A0A3M8ER53|squalene-hopene cyclase|EC 5.4.99.17|Desulfuromonadales bacterium|TrEMBL
MKISKHPISHALTSFNDIARDTDEQKPQKRGGKVHHLPASIWKKRETEASSPLDRTIERS
QEFFFREQLPAGYWWAELESNVTITAEYIMLFQFMGLVDKVKQRKMARYILSKQTEEGYW
CLWYGGPGDLSTTIEAYFALKLAGYPADHPAMQKARAFILENGGILKARVFTKIFLALFG
EFSWMGIPSMPIEMMLLPNGFTFNLYEFSSWSRATIIPLSIVMAERPVRKLPPWARVQEL
YVRPPRPTDYTFTKEDGILTWKNIFIGIDHILKIYEASPIRPGKKKATAIAEQWVLDHQE
PTGDWGGIQPAMLNSVLALHCLGYANDHPAVAKGLQALANFCIEGEEEIVLQSCVSPVWD
TALGLMAMVDSEVPADHPALVKATQWLLDREVRKPGDWKIKSPDLEPGGWAFEFLNDWYP
DVDDSGIVMMAIKDVKVKDAKARDEAVKRGIAWCLGMQSRNGGWGAFDKDNTKHILNKIP
FADLEALIDPPTADLTGRMLELMGTYGYPKDHPAAVRALQFVKDTQEPEGPWWGRWGVNY
IYGTWSVLCGLSAYGEDMGQPYIRKAVNWLVARQNQDGGWGECCESYYDPKLAGVGPSTA
SQTGWAILSLLAAGEVGHPAVARGVQYLIDSQKPDGTWDEEQFTGTGFPKYFMIKYHIYR
NCFPLMALGRYRAMKRRTD
>A0A7W4PM68|squalene-hopene cyclase|EC 5.4.99.17|Gluconacetobacter tumulisoli|TrEMBL
MMPNATDTLDSSRPAVRDPIVPMADVDRAADRAHAALGRRQNDDGHWVFELEADATIPAE
YVLLEHYLDRIDPALEARIGVYLRRIQGDHGGWPLYYGGKFDISASVKAYFALKAIGDDV
DAPHMARARAAILDHGGAERSNVFTRFQLALYGEVPWHATPAMPVELVLLPRKAFFSMWN
MSYWSRTVIAPLLVLAALRPRAINPRGVHVQELFVTPPSRIRDWIRGPYRSPLGRVFRYV
DKVVRPAERLIPETTRRRAIKAAVDFIEPRLNGVDGLGAIYPAMANTVMMYRALGVPDSD
PRAATAWEAVRNLLVENGEETYCQPCVSPIWDTGLAGHAMIEAASGPDGVRPEETRQKLA
AAAAWLRDRQILDVKGDWAINCPDVEPGGWAFQYRNDYYPDVDDTAVVGMLLHREGDPAN
DEAIERARQWIIGMQSSNGGWGAFDIDNNLEFLNHIPFADHGALLDPPTADVTARCISFL
AQLGHPEDRPVIERGIDYLRSDQEKEGCWFGRWGTNYIYGTWSVLCAYNAAGVAHDDPSM
VRAVEWLRAVQREDGGWGEDCASYEGATPGIYHESLPSQTAWAVLGLMAAGLHGDPAVAR
GMAFLTRMQNEDGEWDEEPYNAVGFPKVFYLRYHGYRQFFPLMALSRYRNLASSNSRHVA
FGF
>A0A8I2DW20|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. RM72|TrEMBL
MTATTDGSTGASLRPLAASASDTDITIPAVAAGVPEAAARATRRATDFLLSQQDAQGWWK
GDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDSPDAPHMARAAEWIRSRGGIASARVFTRIWLALFGWWKWDDLPELPPELI
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPARPNPPRPLAPAA
SWDGAFQRIDKALHAYRKVAPRRLRKAAMNSAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPEDHP
QLVKASDWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHH
DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAVEGLAHDPRTRRGIQWLLDAQEADGSWFGRWGVNYVYGTGSVIPALTAAGLPTS
HPAIRRAVRWLESVQNEDGGWGEDLRSYRYVREWSGRGASTASQTGWALMALLAAGERES
RAVERGIEWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFA
KKPRGAQAPTEPATAEVKGS
>A0A840N7M9|squalene-hopene cyclase|EC 5.4.99.17|Saccharopolyspora gloriosae|TrEMBL
MTTLQAEEISRVIDAAAEAVFAVRRPDGVFDYGGDGLTSTLSTVGAVSALHFADPHGSAD
LIERGVAWLRARQSAGGGWSMIPGEPDEPGPTAVAAATLHLVAPDDAADAVAAGLRWMRE
FGGLEAIPHPEVTAWCRQFYSFVGWLEIDEMRRFPLELTLLRGPFQRLFDLRAPMVCALG
LAQAAHRKQTPLTRLLSKAGTPRALSIIRQVYEHEGSTGGWCEDAWVTGLICGGLARAGL
GEDMVAGAVRWFREQANDDGSWNSGPLELTWSMYAAGGLLEAGYATDERLLATREIFLRD
QQDRPFTAFGCPPGFWGWSGARGWPASLETGEIMSALARYPGDRHRPALDAGASWLFAQQ
DTRGSWGLCVRNTKVANSGPCPHMTVQSLDGLLDSGVPASDPRVQKAVTWLQSAQQPDGS
YESVWYRMHTAGTSAVLQTLVRAGAGESDAARGARDWLMRAQLADGSWGTGGDEPGTVEE
TAWAVGALLVAGSGTANAEVRRGVRWLVDARRPDGSWPAAPVNEYVRHVSRYANRALANG
LALRALARYRDRAGRD
>A0A7X8UBX6|squalene-hopene cyclase|EC 5.4.99.17|Acidobacteria bacterium|TrEMBL
MREPLAIVSNPDVVIEETAPAARTVVRASAHEVRETAVRAARTLASKQYEEGYWVGDLTA
DSTLQSDYILLQMWLHPADADGSWNPPTLTRVRKAARAILDAQRPDGGWNTYEPGPSEIN
ATVRAYSMLKMTGMSPEDPRMKRARELVLKLGGLQACNSYTKINYSFFDLFPRKYCPTIP
PEILILPGNLLYEMSSWTRTIIVPLSIIQAIGKTRPTPGGMRIDELMHPHRKLALHRRDR
IGNIFIKADTLFKRWERQSVQKIRGRALREAEHWMLDRLQFSDGLGAIYPAMMYAIMAMD
SLGYERDHPDLVQAIGQFDGLMLEGEESLIFQPCKSPVWDTAIAAFALGELGEADPARMT
AAADWLLDREIRRKGDWAAKRPGLTPSGWVFEFANEFYPDMDDTAMVLLALLHARASDPQ
RQARAERRAVRWLLGMQSSDGGWAAFDVDNNWEIFNSIPFADHNAMLDPTCPDITGRALE
SLCRRGFKYTDSPVARGIDFLLRHQEINGSWFGRWGVNYVYGTFLAIRGLAATGAPHAKT
AIALAARWLREVQNPDGGWGESCLGYHTRRFEPAESTPTQTAWAVLGLIAAGEVYCSAVQ
KGIRWLQERQRPDGSWDESVTTGTGFPQVFYIHYHLYRDYFPILALGTYARRAEAQPAGD
RVQ
>A0A5J5K242|squalene-hopene cyclase|EC 5.4.99.17|Microbispora cellulosiformans|TrEMBL
MTALVTAASRAATALEAARDHLLALQSPEGWWKGELQTNVTMDAEDLLLREFLGVRTAAE
TAEAARWIRSQQQAGGGWANFHDGPADLSTTVEAYVALRLAGDPPSAPHLRAAAGLVRDL
GGVESARVFTRMWLALFGLWRWEDLPVIPPEIVFLPPWCPLNVYDWACWARQTIVPLTIV
TAHRPVRPLPFGLAELRTGRRPPSPPRTSVDTAFAALDHVLHRYERRPLAGLRRAALRRA
AEWVVARQEADGSWGGIQPPWVYSLVALHLSGYDAGHPVMRRGLAGLDRFTIREDGSRRL
EACQSPVWDTALAVIALLDAGLPRDHPALDRAGEWLLREEIRGPGDWAVRRPGLAPGGWA
FEFDNDGYPDVDDTAEVILALGRWGRPAARDAVRRGLRWMAGMASRDGGFAAFDADNTRA
LCLRLPFCDFGAVIDPPSADVTAHVVEALAAEGEARSPAVRRAVTWLLRAQEPGGSWFGR
WGANHVYGTGAVLPALAAAGVPPAAPCVRRAVAWLEAHQHPGGGWGEDMRSYRDPAWIGR
GEPTASQTAWALIGLLAAGERGPSVERGVAWLAGTQRPDGTWDEPHYTGTGFPGDFYINY
HLYRLVFPVSALGRYLQAREGTR
>A0A7Y5NZ39|squalene-hopene cyclase|EC 5.4.99.17|Streptomycetaceae bacterium|TrEMBL
MTVTVRTEAGHAPDQAKDTLDRAVAHLLSVQSDVGWWKGELETNVTMDAEDLLFREFLGI
RSAEQTEQTARWIRSNQREDGTWASFRGGPAELSTTVEAYVALKLAGDAPDAEHMQRAAA
FIREHGGVPHTRVFTRIWLALFGWSSWDELPVMPPELIYFPKWFPLNVYDFACWARQTIV
PLTIVNAFRPVRKSPFPLDELAPTGFVPPKPVDTDPWSKFFRTADKALHVYSKKPVQPLR
RNAMRRATQWIIQRQEADGGWGGIQPPWVYSLMALHLMGYPLNHPVMAQGIKGLDGFTIW
EDTPEGTVRRFEACQSPVWDTGLSLVALRDAGLPGDHPQVVKAADWLLDEEIRERGDWAV
RRPNLEPGGWAFEFANDYYPDTDDTAEVVMGLRYAEHPDPERKAAVLGRAEVWTAGMRSK
DGGWGAFDADNTSVLPLKLPFCDFGAVIDPPSADVTAHIVEMFAESGPEYRDQVVEGVRW
LLRNQEPDGSWFGRWGANYIYGTGAVVPALVLAGVDPRHSAIRRAVRWLYKVQNEDGGWG
EDLRSYIDKSWSGKGDSTASQTAWALMALLAAGERGPAVDRGAAWLASRQNAEGGWDEPQ
FTGTGFPGDFYIKYHMYRIVFPIMALGRYVKTIA
>A0A845J153|squalene-hopene cyclase|EC 5.4.99.17|Amycolatopsis rubida|TrEMBL
MTQTVPRTSAPAARTADGTVAAAVEFLRREQDRAGWWKGELATNVTMDAEDLLLRHFLGI
LTPQVAEESARWIRSQQRADGTWANFPDGPADLSTTVEAWVALRLAGDPADAPWLAAAAE
WIREHGGIEATRVFTRIWLAMVGQWSWDDLPSLPPELIFLPSWFPLNVYDFACWARQTIV
PLTIVGTLRPVRKLPFDVSGLRTGKRPPKTRAPWTWDGVFQNLDTALHAYAKLPLNPVRK
LAMKQTAEWILARQEADGSWGGIQPPWVYSILALHLLGYPLDHPALKAGIAGLDGFTIRE
KTGQGWVRRLEACQSPVWDTALAMTALLDAGVSPGDETLVRAAEWMLGEEIRVPGDWAVR
RPSLKPGGFAFEFANDGYPDTDDTAEVVLALRRMGRPDHLRIREAVDRSVAWLEGMQSSD
GGWGAFDADNTQALATRLPFCDFGAVIDPPSADVTAHVVEMLAAEGKSGTRECRRGIRWL
WDNQEEDGSWFGRWGANYVYGTGAVVPALVAAGIPGSDRRIRRAVKWLAEHQNDDGGWGE
DLRSYDDRAWAGRGDSTPSQTAWALLALLAAGERESAVVARGVEWLVERQRPDGGWDEDK
HTGTGFPGDFYLSYHLYRVVFPLSALGRYVRGGS
>A0A7C3X6F0|squalene-hopene cyclase|EC 5.4.99.17|Armatimonadetes bacterium|TrEMBL
FMIRDERGTRLQPCVSPVWDTAIALNALLEAGVSPSAAGIQAALNWLLDREVRRPGDWSR
TVRGVEPAGWAFEYRNEFYPDVDDTVMVLMALNKARTNPNAERLDSATYRAVRWILAMQS
RNGGWAAFDKDNTRVLLQYVPYADHNAMLDPPTADITARVVECLSQLGISHHHPAIRRAV
SYLLEEQEPDGSWYGRWGVNYIYGTWQALRGLSAAGFPASHPAVQKALRWLVSIQHEDGG
WGELPDTYNDPTRKGQGPSTASQTAWAVMGLMAAGAVESDACQRGIAYLLETQRSDGSWD
EEQFTGTGFPRVFYLRYHYYRHSFPLWALGVYARALEAAS
>A0A7K2PAW3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5926|TrEMBL
MTATTDGSTGASLRPLAASASDTDITIPAAAAGVPEAAARATRRATDFLLAKQDAEGWWK
GDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDSPDAPHMARAAEWIRSRGGIASARVFTRIWLALFGWWKWDDLPELPPELI
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPARPNPPRPLAPAA
SWDGAFQRIDKALHAYRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPEDHP
QLVKASDWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHH
DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNT
>A0A522QFU7|squalene-hopene cyclase|EC 5.4.99.17|Jatrophihabitans sp|TrEMBL
MTALPRAGSSLAERTDAALEQASAFLTARQHRDGWWKGELRTNVTMDAEDLLMRQFLGIL
LEEDLAQTARWIRSEQRADGTWATFPGGPGDLSTTVEAYAALRLAGDLPDAPHMAAAAAF
VREQGGIAACRVFTRIWLALFGEWPWDQLPAMPPELVLLPRWVPLNVYDWACWARQTVVP
ITVVATLRPVRRLPFALPELHVGPRRSRRGAGPAGRLFGLLDFALSWYGALPVQPGRELA
MRRAAEWILARQEADGGWGGIQPPWVYSILALHLLGYPLSHPALVAAVAGLEGFLVREQT
PDGPVRRLEACQSPVWDTCLAVTVLLDAGVDPHDEAIARATDWLVGEEIGVRGDWAVRRP
RLAPGGWAFEFANDGYPDVDDTAEVVLALDRVPDRPGLPGAIERGVRWTVGMQSRDGGWG
AFDADNTRRLVEQLPFCDFGAVIDPPSADVTAHVVEMLAARGLAAGDPCRRGVRWLLDAQ
EPDGSWFGRWGANHVYGTGAVVPALVAAGLSAASPPVTRALGWLVAHQNPDGGWGEDMRS
YRDPAWRGRGASTPSQTAWALLALLAADGDAQAVERGVGWLLDTQREDGGWDEPFHTGTG
FPGDFFITYEMYRDVFPLSALGRFRRALG
>A0A525KB36|squalene-hopene cyclase|EC 5.4.99.17|Phenylobacterium sp|TrEMBL
MNDVAPALTASQTVLDGRIRRAAEALLRRQNADGHWVFELEADATIPAEYVLLRQFLGEA
DDLELERKVGVYLRRIQGAHHGWPLVFGGPFDISASLKAYYALKMIGDDPDAPHMAAARA
AIRAHGGPNAANVFTRIQLALFGQMSWARIPTMPIELILLPRWFPIHLSKMSYWARTVIV
PLLVLQTRKPVARNRRGIGIAELYGGAADIKPASKAAATKRLWTVGFNALDAVLKAVEGL
WPKRLRARATQACVDFVAERLNGVDGLGAIYPAMANSVMMYDTLGFGADHPDRAAARESV
ERLLVVKDDEVYCQPCVSPVWDTALTCHALLELGGDVAEDAAAQGLDWLIPRQVLDVKGD
WAEQRPDVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRARHREGGRFDAAIARGTEWVEGL
QSRDGGWGAFDADNSFHYLNNIPFADHGALLDPPTDDVTARCVSMLAQLGKDRSDPQVKA
ALAFLAKSQMADGSWFGRWGVNFVYGTWSVLCALNAVGLSVEDPMVRRAADWLVAIQNAD
GGWGEDCESYDLNYAGHRPAPSAASQTAWALMGLMAAGLVDHPAVQRGVAWLAANEDDEG
FWPEPGYTGGGFPRVFYLRYHGYSKFFPLWALARYRNLTRANSRRVGFGM
>A0A7X0M7U8|squalene-hopene cyclase|EC 5.4.99.17|Sphaerisporangium rubeum|TrEMBL
MGSEIITTGPHFDVEGGVAGAVKALWDAQRADGSWEGYLPSSAVSTAAVLIAFHVAGDLS
DATLVERGAEWLLAEQNEDGGWADVPGGPSTFNGTGIAVSALRTVRPDRVDAITRATDWL
ERNGGRAALEDLRVTTLNVIVRVYLAFAGLYDPDRVKRIPIEISLIPHRLHQRVSFILPG
VYAWAIMQVRTRTHGRVRTAVNRVAERRTLEYLRELAEFEGPDGGSEESAFMVALIVFGL
GLAGVGDDLVTKYLRYMRNAVRPDGSWPIDRDLELSGTCYITQGMQEAGLGDDDRLLPTI
DWIKASQRQTGLPATGCPPGGWGWGMPSSWPDVDDTSLALYTLAGAGVPPTDPHVAMGVD
WLHAMRNTNGSWGCFIRNGRTMFDAPCSALTSHAILALNRLDSREHHLDRAVRWLAKAQN
PDGSFSCVWFRDHTSGTARVLDALSHLGLSDHPVARACTHWLQTHQSPDGGWGDGAGLPP
TAEETSWSVLALTAAGQAATPTVRNGIHWLLKNQREDGLWPGGQVGYYYNGLTYWCHSMV
NGYALQALSRYRTH
>A0A7W6AK87|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium brachythecii|TrEMBL
MREAAVDRMNSKVESLQRVKTRDVSLDTVERSIQAATRSLSDLAQSDGHICFELEADATI
PSEYILYHHFRATEVKPGLEQKIGAYLRRTQSPHHGGWSLVHDGAFDMSASVKAYFALKM
IGDDIEAPHMRKARAAILSRGGASNANVFTRFMLALYGEVPWTAVPVMPVEIMHLPKWFP
FHLDKVSYWARTVMVPLFVLQAKKPLAKNLRGIGVQELFVTPPASVRTWPGSPHAAWPWT
PIFGAIDRVLQKTQDYFPKTPRQRAIDKAVAWVSERLNGEDGLGAIYPAMANSVLMYDVL
GYPKDHPQVKIACEAIEKLVVEKDDEAYVQPCVSPVWDTALSGHALLEAGGAQAEATARD
GLDWLKPLQVLDIKGDWAAAKPDVRPGGWAFQYANPHYPDLDDTAVVVMAMDRAMRQHGL
VSDMPDYSASIARAREWVEGLQSADGGWAAFDADNNHHYLNHIPFSDHGALLDPPTADVT
ARVVSMLSQLGETRETSRALDRGVTYLLNDQETDGSWYGRWGMNFIYGTWSVLCALNAAG
VDPSHPQVKKAAAWLIRIQNPDGGWGEDALSYKINPEFEPGKSTASQTAWALLALMAAGE
VDDPAVARGINFLSRTQGADGFWSEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLK
KSNTGKVAYGI
>A0A370NTA0|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus lacunae|TrEMBL
MSMNETVFANATPRIDPAPAQPASAQDLPASHQPKPALDHGIGRAIDALLHQQRPDGHWV
YELEADATIPAEYVLMVHYLGEDPDLDLEARIARYLRRIQNPDGGWPLFHEGRSDISASV
KAYFALKMAGDDPQAAHMQRARQAIHAMGGAEASNVFTRTLLALYGVLPWSAVPMMPVEI
MLLPQWFPFHLSKVSYWARTVIVPLLVLNSLRPQARNPRGVGINELFVGNCHTVGLPPRA
AHQHAGWYTVFRGLDALMRVAEPLFPRMLRRRAIAAAQAFVRERLNGEDGLGAIFPAMAN
SVMMFDVLGVPPGDPARAVARRSVERLLVEHGDEAYCQPCLSPVWDTSLAAHALLETGEA
RAAQAAGRGLDWLKPLQVLDVRGDWVVRRPLVRPGGWAFQYANAYYPDVDDTAVVAAAMD
RFMRAHDAPGRYDEAVARASEWIVGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDPP
TADVSARCLSMLCQTGATPDKSEPAARALRYLLAEQMPDGSWFGRWGTNYIYGTWSALCA
LNAASLPPEAPEMRRAVDWLVQIQNADGGWGEDGSSYRLDYRGYEPAPSVASQTAWALLA
LMAGGAAQHPAVARGIDYLLRTQQTGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWALA
RYRNLQRASAGQVSWGL
>A0A538NIR5|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia bacterium|TrEMBL
MKRSSDVISLPSARPDLAHLYSASDAEISRAISSAQENLLGQQKPDGHWCGELIVDSTLC
SDYVLFMHWCGEVDARLQRRCVRHILKRQLADGGWNTYHGGPSEINASAKAYFALKLAGC
SADAPFMQEARANIMRLGGIPQMNTFSKLYLALLGQFPWKYLPTIPVEMVLLPGWAPFHI
YKMSSWSRAMLIPLAIINHFKPTRVLPGEKQLHELYPLGTEQSDLRLSRSERFWTWRNFF
LRVDDVLKFLRPLGFRPMRRRALEEAERWMLERIGEGSDGLAAVFPAMLNCLIALRALGY
SKRNPVYAKAERDFAALFIDDPENFRIQPCLSPIWDTAINIISLAESGVSAEHPALQKAA
DWLVNKEVRIRGDWAVNNSHPEASGWAFEYNNIHYPDTDDTAMVLMALRLVQPKDRQALN
EIFRRALGWQLSFQCNDGGWAAFDKEVTTPWLEDMPFADHNAILDPTCSDLTARTLELLG
YVGFDAKTRCVRDAIQYLIDTQDDDGSWYGRWGVNYIYGTWQVLRGLRAIGQDMTQDWIL
RGRDWLESCQNNDGGWGETCGTYDNPSTKGIGESTASQTAWAIMGICACGDLDRRSIQRG
LRYLLNSQKPDGSWDEEQITGTGFPRVFYLKYDMYRQNFPLLALATYVNYRSGLGHHPSF
YRCDR
>A0A822L652|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa PCC 9432|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSDGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKALDNFAIE
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKSVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRHQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYQALI
>H8FNB7|squalene-hopene cyclase|EC 5.4.99.17|Magnetospirillum molischianum DSM 120|TrEMBL
MRSDVFASEVKPRSNDSTIAADRLEDAVRGSAAALMSSQKEDGHWVFKLEADATIPSEFV
LYLHYLDERDPPLERRIGVYLRDIQDKTHGGWPLFHGGEFNISASVKAYFALKAIGDDIN
APHMKRAREAILAHGGAATSNVFTRTLLALFGQIPWKGVPVMPVEIMLLPRWFPFHLDRV
SYWSRTVIAPLIVLMSLRPQARNPLKIGIPELFTTPPEQVTNWYIDKPRSHWAYVFRGLD
RVLHQVQPYFPQGLRRLAVERAVAFVDERLNGEDGLGAIFPAMVNAVLMYDLLGVPKDDP
RVVTAKKSIRNLVVEEGDRAWVQPCVSPVWDTALATHALLEAGGPEAEQSVRRAADWLVE
RQVTDFVGDWAVRRPGLAPGGWAFQYANPHYPDVDDTAVVMAALDRIDPQRYADSIEKGA
VWLRGMQSEDGGWGAFDAENTAHYLNHIPFADHGALLDPPTADVSARCVSVLSVLGERQS
DPVAKEGVAYLLKEQEPNGSWFGRWGTNFVYGTWSALTALNAAGVEHDHPAIRKGVEWLL
SKQREDGGWGEDGRSYWDGEPHGEASVSTPSQTAWALLGLMAVGEAKNPAVARGIAYLVN
TRTKEGLWDEEHYTAVGFPRVFYLRYHGYRQFFPVWALARYRNLTTGNAGPVLHAL
>A0A3L7NHR7|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MSYTGPGTDTRHTMADAESSTLAPPANRSLGDGRRGPPSASPSYPAASPSFPAASPSFPA
ELPAATDSLSHSGRGMGRVSTGNENPVLDACRLTARWLYRHQAADGHWRGPLEGDTILES
EYILILAWAGKLTGAHVPGAVLRILREQLPGGGWAIYRGGPVDISASVKAYLALKLTGHD
PESEPMRRARRAITVAGGPWAVNSFTRFYLALLGQMSYAACPAVPPEIVLLPDWFPVNLR
RVSAWSRTMIVPLSLIWAFKPLRVLPREQGIAELFADASGVHAERVVGRLGGDDLWAKFF
RGVDRVFKTLDAFGIRPLRSRAVAECRRWMLERFDGSDGLGAIFPPIVWSIVALRAMGCS
EESPEVQECWRQLEGLIEHEEDGSTRIEPCRSPVWDTALTLRGLAVDRLARRGQCDADSP
ADARALEAAVDWLLDREVRTDGDWSRRTAPVAPSGWCFEYSNRFYPDVDDTAMVVIAMAT
WRQTLAGEETFCSRRLTRANAAIDRARLWLEALQNSDGGWGAFDRDNNCELLCKVPFADH
NAMIDPSSPDLAGRVLEALGRIGLRQGHPAVDRAVAYLRRSQEASGAWYGRWGVNYVYGA
WQAIEGLLAVGVPKTDHAVVAAADWLAAHQSPCGGWGESPDSYANPACAGQGEPTPSQTA
WALAGLLAAGRHDSPHARRGVQWLVGRQTACGDWEEEAFTGTGFPKVFYLRYHWYRLYFP
LMALGRWSIAAAGNQALGQDRVEVSSAKQSECVEVAAANANRVCADNGAAREREKVA
>A0A523NLD6|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MSAPSQQSIAEAHRRAAEALLSLQQADGHWRGELQGDSILESEYLLMKFILGQEDEPMAD
GRPGGEVLGRIAAYMRSLQREDGGWGQYPGSAVDVGATAKAYFALKLMGDDPDAPHMARA
RRAVIELGGAENCNSFTNFYLACLGQISWNAVPEIPPEIILLPRWFYFHLSKVSAWSRTM
IMPLAIVSALRPTRRLPEHLGIGELFVDERNRHRLQNQRPAPLGWSVFFNAIDRMFKLSR
RFGLLPLRRLAMQRAERWILDRAGHGDVVTDGMGAIFPPMVYIQVVFKALGYDREDPAVQ
RAERELDALFIEEPDAIRIQPCFSPVWDTGIATYALTERHGAEYAEAVRTSSRWMLAREC
RHTGDWTNNARTRVTGGAWWFEYRNGWYPDVDDTAIVLMALSRVGDRRSLAASRRAAQWL
LAMQNDDGGWAAFDRTKDRRILEYVPFADHNAMQDPSCPDITGRVIEALATCGFTNRDQA
VRHGIEYIRNCQHPGGGWFGRWGVNYVYGTWQSLVGLIECGEDPNQEWIQRAGRWIKSVQ
KPDGAFGESANSYEDDSLRGQGPSTASQTAWGAMTLQSIYGGHDPDLQRAIAWLVRTQLN
QADADDPVYNPDGDPAGSWVEQWFTGTGFPRVFYLRYH
>A0A7Y3UI22|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MTNLLFDFIEKIDRVSYKFLNGRNGGVVHKVNPKKLCLGKPLEETANSFTCNSKLHTTIK
KAQDHLLKEQDKREGFWVGELEGDAALTAEYIMLMHFIQRVDKKKQEKAAQFLLRTQQED
GGWNIYYKGPGEISVTVKCYFALKLAGHSQEDSFMEKARRCILDLGGITKSNTFTKIYLA
IFGQYDWQGIPALPIEIILFPNSFYFNIYEMSYWSRCIVVPLGIVMAMKPRRNIGGEAAL
DELYVLQKDKVRYRLERDKGIFSFKNIFIMLDSILRRYEKSPYIPLRKLAIEKAEKWLLQ
HFEKSGGLGAIWPAMVNSVMAMKCLGYKDEHPVVKKALIEIEKLEVHDNDSLHMQPCVSP
VWDTPWSILSLSESGLPHDHPALIRAGEWLLEKEVRSFGDWSLKNPVKEPSGWYFQHANE
FYPDNDDTTVVLMALQRIDLPDKARQRDSILRGFKWFLGMQCNDGGWGSFDQNNNKAILN
HIPFADWNALLDPSTSDITARALDVMGRLGYDVNFPPAKKAVDFLKKEQEEDGSWFGRWG
VNYIYGTWSVLSGLYSIKEDMTKEYVKDAASWLKNVQNSDGGWGETCKSYSNTSLKAIGQ
STVSQTSWALLGLLCTEERDSESVEKGIQYLINNQKEDGTWDEEEFTGTGFPQVFYLRYH
MYRSYFPLLALGKYRNMVK
>A0A7W7U432|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces nymphaeiformis|TrEMBL
MTATTDGSTGAMGPRAAAASKANDSDATASGPDGTGAPGASGPDGTGAGAGPVPDGTTAP
GAPGLDGTAARAVERGVEHLLARQDPAGWWKGDLETNVTMDAEDLLLRQFLGILDADTTR
AAALHIRRGQHEDGAWATFYGGPGELSATVEAYVALRLAGDPPEAPHMARASAWVRARGG
IASARVFTRIWLALFGWWRWEDLPELPPELIFLPKWFPLNIYDFGCWARQTIVPLTIVSA
KRPVRPAPFPLDELHTDPARPNPPRPLAPATGWDGVFQRLDKALHVYHRFAPRGVRRTAM
NAAARWIVERQENDGCWGGIQPPAVYSVIALHLLGYDLKHPVMRAGLESLDRFAVWREDG
SRMIEACQSPVWDTCLATIALADAGLAPDHPALVKAVDWMLDEEITRTGDWAVRRPELPP
GGWAFEFHNDTYPDIDDTAEVLLALRRVRHPDPARVDAAVARGARWTLGMQSRDGGWGAF
DADNTSAFPNKLPFCDFGEVIDPPSADVTAHVVEMLAYEGMTEHPRARRGIEWLLAAQEP
NGAWFGRWGVNHVYGTGSVLPALAAAGLPASHPAIRRAVGWLGSAQNDDGGWGEDLRSYK
EEEWVGRGPSTASQTAWALIALLAAGERDSEPVRRGVAWLAETQREDGSWDEPYFTGTGF
PWDFSINYHLYRQVFPLTALGRYVHGEPSPRKED
>A0A7D7X142|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces lincolnensis|TrEMBL
MTATTDGSTGALPPRAAAASETDIRISVAAGVHEAAVRATQRATEYLLSRQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDEATTRAAALFIRGEQHDDGTWGTFYGGPGELSATIEAY
VALRLAGDAPDAPHMAKASAWIRERGGIAAARVFTRIWLALFGWWKWEDLPELPPELIYF
PKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPADPNPARPLAPAASW
DGAFQRLDRTLHQLRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHPQL
VKAADWMLGEEIVRPGDWSVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHDP
ERVENAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIQWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALVAAGFPGSHP
AIRRAVAWLEKVQNDDGGWGEDLRSYKYVKEWSGRGASTASQTAWALMALLAAGERDSKA
VERGVEWLASTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFSGA
KEG
>A0A5N8WTR6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces acidicola|TrEMBL
MTATTDGSTGAPPPRAASASETETDIDTLGVAGVPDAAVRATARATDFLLSRQDAQGWWK
GDLETNVTMDAEDLLLRQFLGVRDDRTTQAAALFIRGEQREDGTWGTFYGGPGELSTTIE
AYVALRLSGDAPDAPHMAKASEWIRARGGIASSRVFTRIWLALFGWWKWEDLPELPPELI
YFPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPRDPNPAAPLAPAA
SWDGVFQRLDKVLHGYHKVALKPLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIAL
HLLGYDLQHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATTALVDAGLPADHP
QLVKAADWMLGEEIVRPGDWAVRRPGLPPGGWAFEFHNDNYPDIDDTAEVALALRRVKHP
DPERVNKAIARGVRWNLGMQSRNGAWGAFDVDNTSPFPNKLPFCDFGEVIDPPSADVTAH
VVEMLAVEGLAHDERTRRGIEWLLTEQEPNGSWFGRWGVNYVYGTGSVVPALVAAGLPAS
HPAIRRAVAWLEAVQNDDGGWGEDLRSYHDVAGWSGKGASTASQTAWALLALLAAGERES
KTVERGIEWLAGTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFT
DRSDTTDTTAAPVKGS
>A0A2X1INF5|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cepacia|TrEMBL
MIRRMTQSTLSPWSALDTAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDLRQERMARYLRANQRLDTHGGWALYVDGDPDVSCSVKAYFALKAAGDSEHAPHMVRA
RDAILKLGGAARSNVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNVSIRELFVTPPDEERRYFPPARGMRKLFLALDRTVRHVEPL
MPKGLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMQVLGYPDDHPLRRDCENAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVAVPEDGEPDDARRALDARIARAY
DWLAERQVNDLRGDWIENAPADVQPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRTHRNA
DGTNPYATRVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRADERASLARCIEYVKRTQQPDGSWWGRWGTNYIYGTWSVLAGLALAGED
KSQPYIARAIEWLRSRQHADGGWGETNDSYIDPKLGGTNGGESTSNFTAWALLAQMAFGD
CESDSVKRGIAYLQSVQQEDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GAAAAAPAAVDAVDTAVA
>A0A536EHT7|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MPSDALAAATDWLLSQQNRDGWWSGELETNVTMTAEHVLLLRFLGLPHDDIRAGAIAHVL
GAQREDGTWALYDHGPGDLSTTIEAYVALRVLGVDSSRDELRRALRFIRMQGGVAEARVF
TKIWLALFGQYPWDGIPSMPPELVQLPPRVPLNLYDFACWARGTIAPLLIVISRRPVRPL
GFDVSELVAPETAHRLRTVPGSGAFWWLDHALKLYDHSHWQPGRRRSRRRLVEWICARQE
ADGSWGGIQPPWVYSLIALNLEGMSLEHPVMARGLEGLRRFTLDDGTHGWRLQACMSPVW
DTAWSLIALRRAGLGRDHPAIRTAVDWLLGEQITSGGDWQVKVPMDSCGGWAFEFDNDTY
PDIDDTAVVVLALLEAGDPDRVAPAVKQAVRWCRAMRSTGGTWGAFDKDNTRALVYSLPF
ADFGAMLDPPSEDVTAHVVEMLAATGSTATDPHVAPGIAYLRREQRPWGSWFGRWGVNHI
YGTWCVVSALRALHSCGTAVERATTWLARAQNPDGGWGESCLSYDDESFAGVGESTASQT
AWAVHTLQLAGLAANPAAAHGLAWLRERQRGGTWDETEHTGTGFPGDFYINYHLYRHVFP
TLALAGESASVPSDAATPQVASTEGEVAPAARQHTYA
>A0A6I7YSA3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. me109|TrEMBL
MTATTDGSTGAVPPRAAAASETHPETTPVAAGTVETRDVAKIAIERAVDHLLARQDAEGW
WKGDLETNVTMDAEDLLLRQFLGIRDEKTTHAAGLFIRGEQREDGAWATFYNGPGDLSAT
VEAYVALRLAGDAPEAPHMTKAAAWVRERGGIASARVFTRIWLALFGWWKWDDLPELPPE
LIYFPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPDHPNPVEPIAP
MASWDGVFQRLDKALHQYRKVAPGPLRRAAMNAAARWIIERQENDGCWGGIQPPAVYSVI
ALHLLGYDLEHPVMRAGLESLERFTVWREDGARMIEACQSPVWDTCLATIALADAGLPAD
HPQLVKAADWMLGEEIVRPGDWSVKRPHLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVR
HHDPERVEKAIGRGVRWNLGMQSKDGGWGAFDVDNTSSFPNRLPFCDFGEVIDPPSADVT
AHVVEMLAVEGLAHDPRTRRGIEWLLAEQEPNGSWFGRWGVNYIYGTGSVVPALAAAGLP
ASHPAIRRAVGWLETVQNEDGGWGEDLRSYDDAAEWSGRGASTASQTGWALLALLAAGER
DSKAVERGVAWLAETQLADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEP
FIEVKGG
>A0A0E3NGJ4|squalene-hopene cyclase|EC 5.4.99.17|Methanosarcina thermophila CHTI-55|TrEMBL
MDDRVSSKQFSGNQVLNGQIPGDEMLKGVNGQIPGDEMLKGVELAIQKSSNFIISNQAGE
GYWLDFYILGMGKSSQWVTAYIAYNLSRLPNTDESVQKAIIWLLHTKFPSGGWGYHQNCL
PDADSTANTVRLLAYYFKKENLLTQENFALYLHEFARMLSFYQDKNTGGFLTYLPGSNGK
YHTMPDSAWCISEPSITAMAGSAFLNAGPELFEQEISSARKFLISRQNPAGYWDSYWWDC
RIYGTSLACSFLKQLGETDPVEKAISWLKSIFVPSKGWGNGYEAVPYPFYTALSLSSLLL
YEDNVHSREVKESLIWLVENQNEDGSWFSKPILRVPDPQVQEPWESSNREKCEVVTDVNL
LFTTATVMGVLYDFLNLCGYKYRSASQK
>A0A7C7J1K7|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirales bacterium|TrEMBL
MEQSIHYLLNQQDPRGFWVAELEADSTLTSEYIMLRRMLKKVDPEKERKKVSYLKAAQCA
DGGWPIYYGGPSNISASVKAYFALKLAGVSPDEPSMHNAREVILKMGGVVNTNVFTKIAL
ALFGQYDWQGIPSMPPEIILLPKQFPVNIHSVSYWSRVVLVPLLIIYASQPVSQVPKECG
IDELYVVPRNQIHVRRGPPFEADPRPVSWRNLFLLVDFALHLYSQRPLRPLRGLAIKKAT
DWMLERMQGNGGLGAIYPAMANSVLALHALGYGTDHPLVSKALSEIEELEVESEDMLHLQ
PCFSPIWDTCLLTNTLVESGLSRTHPGLLKAGHWMLSQQTKKVGDWKVSAPQAQPGGWCF
QFENEHYPDCDDTAVVLMALAKLDFPNKAEQRQAIIRGLQWLLPMQGRDGGWASYDKDNN
ATMFNEHPFADHKSLIDGSTADIVGRVLEMLGVLGFDQTFPPARKAIAYLKKDQEANGSW
YGRWGVNYIYGTWSVLAGLRSIGEDLSQPYIRKAVHWLKETQHDDGGWGESCQSYADQSL
AGVGESTASQTAWALIGLLCAGEVQSDNVTRGIESLIRSQKPDGSWEERFHTGTGFPRVF
YLRYHWYGQYFPLWAFSMYHSLKTNSRLRADDIAKHNRDQGWYVQHSKKI
>A0A7Y4YGP1|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp|TrEMBL
MNLIRAFLDRLSDSLFVSVPEKLRLATELSKAPPLRLVSDKPMPSTPIDPAMRRPPSHSV
SPVDALDDAVRRSQAWFLSKQDASEGYWVAELEADTTLTSEYIMLRRFLDRVDPERERKA
VRYLRAMQLPDGGWPIFYGGPSEISASVKAYFALKLSGISADEPYMLRARDCIHAKGGVV
CANVFTKITLALFEQYDWEGLPSMPPEIMLLPKRFYFSIYAISYWSRAVLIPLLVVFANQ
PVCRIPKEQGIDELYVFPRAEIRYRDVPPFNKDQRWFTPHNFFVQLDGVLKLYDRMPLSW
LREKALHRAATWMLDHIKGSGGLGAIYPAMANSIVALRCLGYQVDDPLVRKAFQEIESLE
VYSIVSIGDQRVEALHLQPCHSPIWDTALLMNAFIETGMPQDHPSLQKAAAYLASRQTKT
VGDWKFSAPNAEPGGWYFQFENELYPDVDDSAVVLMALSKVRMAQTSELQESIQRGTNWV
LAMQGSDGGWGAYDKDNNRIVFNYIPFADHHALLDPSTSDLTGRCLEMLAALGYDQTHPA
VGPALRFLKREQEADGSWYGRWGVNYIYGTWSVLAGLRAIGVDLSEPYIQRAVTWLESKQ
NPDGGWGESCHSYGDDPAWSGKGDSTPSQTAWAIMGLMSAGMTDAFSVARGIQYLLRHQL
KDGSWEEVRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRTRGHMRADEVREQVLASG
CHRADR
>A0A532DX40|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp|TrEMBL
MNIIKALFNRLSDSLLSTVQGRLDPATELTPGASLRLVSDKPVILASLDSSAARRPIGHA
VSQPDAVDDAIRRSQSWFFNRQHAEGYWVAELEADTTLTSEYVMLRRFLDRVDPDREVKA
VQYLQATQLQDGGWPIYYGGPAEISASVKAYFALKLCGVSADEPFMVRAKERILAMGGVL
QANVFTKITLALFDQYDWEGVPHMPVELMLLPKKFYFSIYAISYWSRAVLIPLLIVFAHR
PVCRIPCEQGIDELYPIPRPEVRYWKYPPFNKDQAWFTPHNFFVALDVMLKLYDRMPMRA
LREKALHKAACWMVDHLKGSGGLGAIYPAMANSIMALQCLGYDADDPLVVKALREIEALE
VYDSTMVNGESVPTLHLQPCFSPVWDTALLMNALVEAGVPQDHPALQKAGRYLMSRQTKA
VGDWIISSPNAEPGGWYFQFENESYPDVDDSAVVIMALSKLKIPGHEDELNESIGRGMRW
VLAMQGSDGGWGAYDKDNNRVVFNYIPFADHKALLDPSTSDLAGRCLEMLGALGYDKTHP
AAGPALAFLKKEQEEDGSWYGRWGVNYIYGTWSVLAGLRAIGEDLSAPYIRRAVAWLESK
QNPDGGWGESCLSYRDDREVHGKEESTPSQTAWALMALMSADAVDSFSVARGVQFLLRWQ
MKDGSWEEISHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRSRGKIRADELRHHIQGT
DLYRSKH
>A0A850DGC4|squalene-hopene cyclase|EC 5.4.99.17|Mycobacteriaceae bacterium|TrEMBL
MGMERYDNAEPEVAEALRRGVDCLLASQSPEGWWKGPLSTCAPADAQDLFLREVLGIRDE
TRVAESGRWIRSLQRADGMWAMYEGGPGELATTVEAFVGLRICGDTMDEPHMRRAADRIR
NLGGVAQTRVVTRFWLAMLGLWSWDDIPVLPPEMILLPRWAPLNIYSWACWVRQIIVPFT
VIGHFRPQCDLGFTLGDLAGDIAARPRAAGAVSTVFHGLDRVLHAYERAPVKPLRATALR
RAQRWILERQEADGSWGGIQPPHLCSIIALWLLGMPLDHPVLAAALRGLDGFVVHEDTPE
GPARWVEVMQGPVWDTALSVLALTDAGTPADHPALKRAADWLLDQEVRTLGDWAVQRPEL
SPGAWPFEFANAQYPDLDDPAAVVRALDRVGGAEAAARRGVAWSAGMQSRDGGWGAFDAD
NTRTLATRLPFCDFADVIDPPSADVTAHLVEMLAEQGGEHAGRVDRGVRWLLAHQERDGS
WFGRWGVNHVYGTGAVVPALIAAGVPPSHPAIRRALEWLAAHQNLDGGWGEDPQSYGDAQ
WVGSGPSTASQTAWALLALVAAGERTPVTRRGVDWLVRAQRSDGDWDEPQYTGTGLPGVL
YIRYPLYRIVFPLSALGRYLAMARERERS
>A0A6G3SFM9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID14478|TrEMBL
MTATTDGSTGAVTPEATSATTAPTTETPPEAPGTDSAAGRAIQRATDFLLARQDAQGWWK
GDLDTNVTMDAEDLLLRQFLGISDKATTDAAALFIRGQQREDGTWATFYGGPGELSTTIE
AYVALRLAGDAPDDPHMAKASAWVRERGGIAASRVFTRIWLALFGWWKWDDLPELPPELI
YFPKWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDARNPNPAKPLAPVA
SWDGAFQRLDKIMHGYQKVALKRLRTSAMNAAARWIIERQENDGCWGGIQPPAVYSVIAL
HLLGYDLEHPVLKAGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPGDHP
SLVKAATWMMDEQIDRPGDWSVSKPRLEPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHP
DRARLERSIERGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTGH
VVEMLAIEGKSHDPRTRRGIEWLLAEQEANGAWFGRWGVNYVYGTGSVVPALTAAGLPTS
HPAIRRAVSWLESVQNDDGGWGEDLRSYRYEDWKGRGTSTASQTAWALLALLAAGERESK
AVERGIRFLAETQTEDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFTD
RADAPVKGS
>A0A7W4NNI1|squalene-hopene cyclase|EC 5.4.99.17|Gluconacetobacter diazotrophicus|TrEMBL
MMANATDTIELPPSRAADRIVPMTDIDQAVDAAHAALGRRQQDDGHWVFELEADATIPAE
YVLLEHYLDRIDPALEERIGVYLRRIQGDHGGWPLYHGGKFDVSATVKAYFALKAIGDDI
DAPHMARARAAILDHGGAERSNVFTRFQLALFGEVPWHATPVMPVELMLLPRKALFSVWN
MSYWSRTVIAPLLVLAALRPRAINPRDVHVPELFVTPPDQVRDWIRGPYRSQLGRLFKYV
DIALRPAERLIPDATRQRAIKAAVDFIEPRLNGEDGLGAIYPAMANTVMMYRALGVPDSD
PRAATAWEAVRRLLVELDGEAYCQPCVSPIWDTGLAGHAMIEAASGPEGIRPEDTKKKLA
AAAEWLRERQILNVKGDWAINCPDVPPGGWAFQYNNDYYPDVDDTAVVGMLLHREGDPAN
DEALERARQWIIGMQSSNGGWGAFDIDNNLDFLNHIPFADHGALLDPPTADVTARCISFL
AQLGHPEDRPVIERGIAYLRTDQEREGCWFGRWGTNYIYGTWSVLCAYNAAGVAHDDPSV
VRAVDWLRSVQREDGGWGEDCASYEGATPGIYTESLPSQTAWAVLGLMAVGLRDDPAVMR
GMAYLTRTQKDDGEWDEEPYNAVGFPKVFYLRYHGYRQFFPLLALSRYRNLASSNSRHVA
FGF
>A0A7C5MEL0|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Solibacter sp|TrEMBL
MTPQLQPCSESLDVSDALARATEHLLHLQHPEGYWWGELTADTTLESDFILLQLFLHPPV
DGVWRPPTSSLIQKAAASILARQLPDGGFNIYPHGPADVSATVKAYFALKLAGLPETSPE
LTRARQVILSLGGIQAANSYVKINLSLFGLYPREHCPSIPPEMILLPGNFIYQMSSWTRT
IVVPLSILHALNPRRPVPDGFHLKELFLPGAPMTYAPSLRRLSWRNLFLGLDRLLKFWDK
HGSRALRRKAIREAERWMLEHTRYSDGLGAIYPPMMYILMALDSLGYSRNHPDFAEAERQ
FFRLLVDDGKRFFFQPCFSPVWDTAIAAFALARAGAPAESLSKASAWLVSKEVRRKGDWA
VKRPGVEPSGWYFEFANEFYPDIDDTAMVLLALRESPGEAPPAVRRAIRWLLAMQSRDGG
WAAFDADNNWKPLSEVPFADHNAMLDPSCPDITGRVLEALCAWGLDCAHPAVRRAVQYLI
RTQEADGSWYGRWGVNYLYGTFLALRGLRAAGQSEREAHILRAAEWIRSVQNPDGGWGES
CAGYDEGCFVAAPSTASQTAWAVLGLLAAGDTASRSLQDGVQYLLKTQQADGSWHEDLAT
GTGFPRVFYLTYHLYRQSFPLLALAEVQKSQSPRPREAA
>A0A7C1S8M2|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MKQSIRTALADRLTGRNKKAARHPQPYPEEERVIKTAVPATSLFTVERLNQVILRARDRF
LTIQNTEGYWIFDLEADTTISSEYIFLQRFLGREIPSRLREGLGRYIRNRQIESGGWPLY
HGGQANISASVKAYFALKQLGDSPEAPHMARAREFILSHGGAVRVNVFTRFTLALFGQIP
WRTTPAMPIEIMLLPRWFFFHLQKVSYWSRTVIVPLLILNARKPVCNLGPEEGIEELFLE
ATEKLRHLDHPAPGNLVKNLFIVLDRVLKAADSLIPAATRQKATRLAESWTIDRMQGEGG
IGAIFPAMANAVMALRVLGYPDDHPDFVRGLKAIDDLLVIRDHEAHCQPCVSPIWDTCLS
LSALLEAGLPPDHEAVKKAVDWLFKKMITTPGDWSLQAPDVEPAGWAFQFENAFYPDIDD
TPMVLMALLRAGALDREEYREKIARAVNWVVGMQSSDGGWGAFDIDNDYFYLNNIPFADH
GALLDPSTSDLTGRCIELLAMLGYGHDFPPIKRALQFLSKEQEECGAWFGRWGVNYIYGT
WSVLKGLGALGEDSTQPYIRKAVHWLKSCQNPDNGWGETSDSYADPSIGGNGRSTPSQTA
WALLGLMAVGEVQSAAVQRGVHYLLETQNQEDLWDEEEFTGTGFPRVFYLRYHGYSRFFP
LWALAEYRRLRTENMTRQDEVTLQSPPDFPLPALKARP
>A0A7V3RWM7|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MRRENEELLKAMGRAQDRFLSQQSPEGWWWYELESNVTITAEYLMLFRFLGMKDPSKERK
MANYILDQQRQDGTWAIYYEGPGCVSTTTEAYFALKMAGVSPKEPRMTKARDFILEMGGM
EATRVFTRIFLALFGQYPWKMLPSLPVELILLPGWFPISVYDFSSWARATLIPISILMDK
KPVVSILPEEGVEELKSGKPLTRPMGWLSWERAFHVLDRVLKALEGLPLRPFHERAIRAV
EEWILRHQEPTGDWAGIQPAMVNSILALRTLGYPIDHPVIVKGLQALERFTIEEKDTLRL
QSCISPVWDTPLTCIALLDSGLPKDHPAFSKAREWLLSRQILVDGDWKVKNPKLEPGGWA
FEFQNDWYPDVDDTAVVLMALKRMWTDGDPGEDPRIQRGIKWAMGMQSKNGGWGAFDVNN
DKEILNKIPWADLEANLDPPTADLTGRMLELMGHYGIPKEHPAARAGIRFLKRVQEPDGC
WWGRWGVNYSYGTWSVLCGLAAIGEDMGQAYVRKAVRWLKDHQNWDGGWGETCDTYRRPE
LRGTGPSTPSQTAWALMALMAAGEVNSPEVERGIKYLLAQQDEDGSWPEPYFTGTGFPKY
FMIRYHNYRNCFPLMALGRYWRLTRQEGE
>A0A534RIC6|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MSASEGRLTLVGGTTGEGLAARVAQAITRASQYLFATQHARGYWHAPLEANASMEAEYVF
FNRLLGRERPDVERRLAERLLALQQADGSWPIYHNGPGGPSTTIEAYFALKLTGMSATEP
ALARARDFILGRGGLARAGVFTRIWLAYFGQFPWAGVPSMPVELVLLPPWFPLNIYAMSS
WARGTVVPLTLLMAHRPSVRLPAEAAVSELWLRAPTREDLAFARSPELVTTRNFFLAVDR
ALKTLAPLSWRGLRRRAVARAIEWVLRHQDTNGQWGGIQPAMVNSVLALHAVGFAADHPA
MVSGIQGVEDFLVECEGTLMYQPCVSPNWDTALAARALLDAGLDPAHPALARAADWLVAN
QIYRPGDWAVLNPTLEPGGWAFEFANDWCPDVDDSAVILMVLDALPAAQTAAGRRAIAYG
LNWTLGMQSHNGGWAAFDTDNTAAFLNRIPFADMEAMIDPPTEDVTGRVLHLMGTVGYRL
DFGRARRAVEFLRRTQRSDGSWWGRWGVNFIYGTWSALAGLERIGEDMRAPYVRRAVEWL
TAHQN
>A0A534RS52|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
LAARALLDSGMEPTHPALERAGEWLVANQIFRPGDWAVQRPGLEPGGWAFEFANDWYPDV
DDSAVILTVLRELPLAATPDGKRAIAYGLNWTLGMQSRNGGYGAFDTDNTTAFLNRIPFA
DMEAMIDPPTEDLTGRLLQLMGGEGYGLDFGRARRAVEFLRRTQRPDGSWWGRWGVNFIY
GTWCALTGLAAIGEDRRAPYIRRAVEWLIARQNADGGWGETVASYDDETLAGRGESTPSQ
TAWALLGILAADGPASAAVERGIDYLVRTQGADGTWTERPFTGTGFPRHFYLRYHLYRHY
FPLMALGHYRAGLAGRSGEEG
>A0A7X7Y9L8|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MIEKRGSMVGSLDVAYDLDDSRLFRIDSESPLRSKKLTLIREHKGPARRPLQPSETVHPV
AVPSSWNRQIVRAIRNCCEHFLQTQHDEGYWWSELESNVTITSEYVMFRYLLGLNDPGKN
RKIAAYLLNHQTENGSWELYYGDGGDLSTTVEAYFALKLAGEDPKSESMLRAKDFILRNG
GVEASRVFTKIWLALFSQYDWDRVPSMPVELVLLPPSCYFNIYEFSMWARSTAVPLSIVL
AIRPRYPLPPEHAIPELNPCSVGETVKKRFASPTHHLFYFFDRIAKFFERHPISSLRNRA
VDAAESWILEHQEETGDWGGIQPAMVNSILALHYLGYPLDHPVMAKGLQAIEDFCLDDDE
GFRMQSCLSPVWDTALTALAFLEAGVPPEHPHLIKATEWLIRNQVTTGGDWQIKNPSPPG
GWAFEFTNNFYPDVDDSAVVLQTLYRMRSSGCAGIESAMERGMAWCLSMQGSTGGWAAFD
KDNELVILNRIPFADQEAMVDFATADVTGRMLEAMGLFGFDRSHHRAEKGIRFLKDRQEA
DGAWWGRWGVNYIYGTWSALRGLVGIGEDPKAPYIQAAVHWIKQHQNGDGGWGETCRSYE
DPALRGQGPSTPSQTAWALMALLVCGEYDSPEVRKGVQYLLRTQRPDGTWDEKEFTGTGF
PKHFFIRYHNYRNCFPLMALGQYLHWIKKSDKGV
>A0A3N7PBX4|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia ubonensis|TrEMBL
MNDLTDMPTLAADSAAADLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYILLVHY
LGETPNLELEQKIGRYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAILAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPIAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYDALGYPEDHPNRAI
ARRSVEKLLVVHDDEAYCQPCLSPVWDTSLAAHALLETGDPRAEDAVVRGLEWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANPHYPDVDDTAVVVMAMDRVEKLRHSDAYRESISRAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETAA
NSEAARRSLDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLGPDDPRVKRGAQWL
LSVQNKDGGWGEDGDSYKLNYRGYEQAPSTSSQTAWALLGLMAAGEVNHPAVARGIDYLI
AEQKEHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>T2AY85|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWFGRWG
>T2AY33|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKIIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFSQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWYGRWG
>T2AZA4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWITSMHSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRVQEVNGSW
>T2AZ00|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWAANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGSDNQAVARAIGYLKRGQEVNGSW
>T2AZG4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PVWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQYW
NDYYPDVDDTAVVVMALHRADPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQH
IPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQTVARAIGYLKRGQEVNGSWYGSWG
>T2B047|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMRAVLEANSVPDKIIMEKAANWPVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHRFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWYGRWG
>A0A1S8G7F4|squalene-hopene cyclase|EC 5.4.99.17|Bacillus mycoides|TrEMBL
MLLYEKVREKVKKEITALQAMQQQDGMWCFCFEGSPLTDCHMIFLLKLLGQDQEIEPFVA
RLASLQTNEGTWKLYEDEPVGNLSATIQVYAALLASKMYTKEDINMKRAEAFIRRQGGIT
KAHFMTKFLLALHGGYEYPSLFHFPTPMLFLPEDSPLSIFELSSSARIHLIPMMICMNKR
FTVSKTILPNLDYISGGSKKQWFREERSPLFQTLLGDVKKFLLYPLSLHHKGDKEVERFM
IERIDTNGTLYSYASATFYMIYAFLALGHSIQSPLISNAVLGLKTYVWNMDRGTHLQNSP
STVWDTALLSYSLQEAGVPHDHQMIQKATDYLLQKQHKEKKDWSVHAPSLDAGGWGFSDI
NTTIPDIDDTTATLRALARSRKGKQKVEEAWKKGIEWMRGLQNIDGGWAAFERGVTSKVL
THLPLDNSGDMVTDPSTPDITGRALEFFGTYAPKELQGDPKDRAIRWLIHTQGKNGSWHG
KWGVCYIYGTWAALTGLRSIGVSSNHIALQKAATWLESIQHSDGGWGESCRSSIEKRFIS
LPFSTPSQTAWALDALIAYYDTETPVIRKGISYLLTHLTQNQDYPTGIGLPDGFYIRYHS
YHHIFPLLTFAHYIKKYRK
>T2B0H8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIFMEKAANWLVKRQILDVIGDWGANVHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDCYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVTRAIGYLKRVQEVNGSWFGRW
>T2AZ55|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLATHAMLEANLSSGPRILENDSTSKACKWLEKLQIRDCAGDWAVWRPNLRPGG
WAFQYHNDYYPDIDDTAVVAMALHRTGNKIYEPALLRAAEWIIGMQSKNGGWAAFDADNE
YHLLENMPFADHGALLDPPSVDVSARCISFLTQLGYDQTNGTIKRGIEYLKKNQEEDGSW
FGRWG
>T2AYQ8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLAAHAVLETLGGNTLLLNKSCDWLSKLQIKEHTGDWGWRRKGLRPGGWAFQYN
NKFYPDVDDTAVVGMALHRQNPEKYADTISRAEEWIIGMQSSNGGWAAFDADNEYYLLEN
LPFADHRALLDPPTADVTARCISFLTQIGTSNNHPISRGLEFLKRNQEEDGSWYGRWG
>T2AXJ3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGIACNALMDAGLPKDHPALIKATEFFFRKQVVKRGDWQVKNPNAESGGWAFEFY
NELYPDNDDTAEILMAIHSIEFPDLRYKLKESQRALSWLLSMQSKNGGWGAFDQDNDQEL
FNAIPFADHNAMLDPPTVDVTSRIIWLLGILGYSREHPQVKKAIVYIISDQENDGSWYGS
WG
>T2B0J9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLSGISLLESGLTLKDIAIKKVCTWLEKKQILEMKGDWVANNKNLLPGGWAFQY
ENDFYPDVDDTAVVAVFLDRAGYQNKKRLERACNWIIGMQSKNGGWGSFDKDNTYHYLNN
IPFADHGALLDPPTADVSARCISMLSQINKKNYKNVIQKGVEFLKNEQEEDGSW
>T2AZF9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGFNGLSLLESGLTLKDSSIQKACKWLEKKQILDIKGDWIVNNKNLLPGGWAFQY
ENDFYPDVDDTAVIVMFLDRAGYQNKKRSEIACNWIIGMQSKNGGWGAFDKDNTYHYLNN
IPFADHGALLDPPTADVSARCISMLSQINKKIIKK
>T2AZZ4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PVWDTGLSGISLLESGLTLKDIAIKKACTWLEKKQILEMKGDWVANNKNLLPGGWAFQYE
NDFYPDVDDTAVVAMFLDRAGYQNKKRLERACNWIIGMQSKNGGWGSFDKDNTYHYLNNI
PFADHGALLDPPTADVSARCISMLSQINKKNYKNVIQKGVEFLKNEQEEDGSWYGSWG
>T2AZC9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTCLSLSALSEGGAPNDHPAVRQAIDWLFDNQIFVNGDWSKNAKGLESGGWAFQYE
NDKYPDVDDTGMVLMALFRAGAHEKDAKKKRLNQALNWVLGMQNPDGSWGAFDIGNNCGY
LNNIPFADHGALVDPGTADLTARCVELLAMLGYGKESAVVTRALRFIQDDQEEDGSWYGR
WG
>T2AZW2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAALALQEANPKATRHSREKAYNWLKTKQLDKQPGDWQIQQPHLNGGGWAFQF
ENPHYPDVDDTAVVAFAMANACDLNNLEESIHRATHWTAGMQSKNGGFGAFDCDNTDYYL
NHIPFADHGALLDPPTADVSARCAMLLGHQLNSHPEYQKTLDKTITYLRKEQESDGSWYG
RWG
>A0A858JIA0|squalene-hopene cyclase|EC 5.4.99.17|Komagataeibacter rhaeticus|TrEMBL
MTFLTGTEKMNKESRPFPPGTTGPVSGKAPQATDGSFRALDNSLSHALSAACDWLIGQQK
PDGHWVGPVASNASMEAEWCLALWFLGLDDHPLRPRLGHALLEMQREDGSWGIYYGAGNG
DINATVESYAALRSLGYAADEPALAKAATWIASKGGLRNIRVFTRYWLALIGEWPWEKTP
NLPPEVIWFPNKFVFSIYNFAQWARATLVPLAILSARRPARPLRPQDRLDALFPGGRANF
DYELPRKEGRDLWASFFRTTDRGLHWLQSRVMKKSSLREAAIRHMLEWIIRHQDADGGWG
GIQPPWVYGLMALHGEDYQFHHPVMAKGLAALDDPGWRHDRGQASWIQATNSPVWDTMLA
LMALHDADGETRFTPEMDRALGWLLDRQVRVKGDWSIKLPDVEPGGWAFEYANDRYPDTD
DTAVALIALSSCRNRPEWQARGVEPAIKRGVNWLVAMQSESGGWGAFDKDNNRSLLAKIP
FCDFGEALDPPSVDVTAHVLEAFGVLGLPRDMPAIRRGLAYIRAEQAADGPWFGRWGVNY
LYGTGAVLPALAAIGEDMTQPYITRACDWLVGCQQADGGWGESCASYMEIAAIGHGPTTP
SQTAWALMGLIAANRPQDHAAIARGCRYLIDLQQPDGRWDEKEFTGTGFPGYGVGQTIRL
DDPALSQRLQQGAELSRAFMLRYDLYRQFFPIMALSRAARVLKAAG
>T2AZP7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDDPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAASWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGSW
G
>T2B0G4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTCIAQLALLESGVAPDDPMVQSSARWLMDKQIFAGGDWQVRAKDTRPGGWSFEFD
NLAYPDIDDASIVVMALERVRLPEAEEPRRADSIKRGVEWVAGMQCKNGGWAAFDKDNNK
KYLTKIPFSDFGETLDPPSVDVTAHLLEMYGRLGYTREEQAVDRGFEYVIGEQEENGSWF
GRWG
>T2AYC2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAALALQEANPKATRHSREKAYNWLKTKQLDKQPGDWQIQQPHLNGGGWAFQF
ENPHYPDVDDTAVVAFAMANACDLNNLEESIHRATHWTAGMQSKNGGFGAFDCDNTDYYL
NHIPFADHGALLDPPTADVSARCAMLLGHQLNSHPEYQKTLDKTITFLRKEQESDGSWFG
SWG
>T2AZD4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGFNGLSLLESGLTLKDSSIQKACKWLEKKQILEIKGDWIVNNKNLLPGGWALQY
ENDFYPDVDDTAVIVMFLDRAGYQNKKRLEIACNWIIGMQSKNGGWGAFDKDNTYHYLNN
IPFADHGALLDPPTADVSARCISMLSQINKKNYKKIIQKGVKFLKNEQENDGSWFGRWG
>A0A849RG95|squalene-hopene cyclase|EC 5.4.99.17|Methyloglobulus sp|TrEMBL
MLTETTSASSLGTAAIEASSIPSSLDNAINKAKTQLLSLQHDEGYWVFELEADCTIPSEY
ILMMHFMDEIDEALQAKIANFLLSQQSADGSYPLYKGGTGDLSCTIKAYYAMKMADYPLH
ATHMKKAREWILAKGGAAQSNVFTRIMMAMFGQIPWRGVPYMPVEIMLLPKWFPFHLDKV
SYWSRTVMVPLFILSTYKVKARNPKKIGISELFITPPNQERNYFAHVKTPLGRAILIVER
MARLLVEPLIPAFVRRKATAKAQDWFMQRLNGYDGLGAIFTAMVNAYEAMDYLGIPADNE
QRRIARIAIERLLVIKDDLAYCQPCVSPIWDTGLTALVLQEVDKYETNPQTQLAIKSGLQ
WLATKQLRDEPGDWQIQRPSLPGGGWAFQFGNSYYPDVDDTAVVALALIQANDLKFAENI
DRAGVWIAGMQSRNGGYGAFDADNDHHYLNHIPFADHGALLDPPTADVSGRCIMFLARLV
NQHPEYRAVIDNCIAYLRKEQETDGSWFGRWGTNYIYGTWSVLTGFESAGVPKNDPSIRK
AVAWLKNKQRNDGGWGEDNYSYHGNNIRGVFYTSTAFHTALALLALLSAGEAGCPEVGAG
VSYLLKTQQAGGFWEDKNFNAPGFPKVFYLKYHGYDKFFPLWALARYRNEITPNRLQN
>A0A839URG0|squalene-hopene cyclase|EC 5.4.99.17|Endobacter medicaginis|TrEMBL
MLDALTPNTLEDCIERAGAWLEGVRQPDGHLVFELESDVTIPSEYVLLMHYLDEIDDGLA
AEIGRYIRRIQADHGGWALYHDGAFDISASVKAYFALKAIGDAPDAPHMMRAREAILAAG
GAAKTNVFTRFQLALFGFVPWRATPAMPVELVLLPATAPFSIWKVSYWSRTVTVPLLVLA
ALRPSARNPRGVRIDELFVVPPEQVRDWHSRSVLGDNWKGRGFRAIDAMLRPAEKLIPRA
TRQKAIDAAVAFVTERLNGVDGLGAIYPAMANSVMMFDALGVAADDPRAATARESLRRLL
VRHETPDGVETYCQPCVSPVWDTALAGHAVLERAQEAGGRTVGEAPAAVGAANEWLLGRE
VRVRGDWSVAAPDLAPGGWAFQYRNDHYPDVDDTAVVGMLMHRSGDPATAAAVERARVWI
LGMQSANGGWGAFDIDNNTDFLNYVPFADHGALLDPPTADVTARCISFLCQLGHAEDRPS
IERGLAWLRSEQEADGAWFGRWGTNYIYGTWSVLCALNAAGLASDDPAVVRAADWLVSVQ
NEDGGWGEGQESYDAGGPRGTYRCSLPSQTAWAVLGLMAAGRVRDEAVSRGVAWLAAHQT
EAGSWDEPQHNAVGFPRVFYLRYHGYRHYFPLMALSRFRNLSASNSARVGWGF
>A0A6B1GZD7|squalene-hopene cyclase|EC 5.4.99.17|Holophagales bacterium|TrEMBL
MIGPAGVLKERSKTAPARNLNQTIEAAARNLLSSRKEDGHWRFELEGDTILESEYVLLLY
FLGRAGDPRVTACCRRLRSQQMPTGGWATYPGGRVDPSVSVKAYLCLKLAGDDPRSPHMA
AARRAILGAGGLRACNSYTKLYLAIFGLWRWRQAPAVPPEMILLPRWFCFNIYDMSSWTR
AMVVPLSVIWAHRPSVPLGVTLDELETEFVPTRARRPLIELLWAQAFSALSALFKLVDWI
GPLPWWRRRALVKAERWLTERIECADGLGAIFGAMVNAVIALRCLGYDLNHPLVQAQLRE
LERFEIEEAGETRLQPCLSPVWDTTLTVNALLDAGVDDGKAPIQEALEWLLDREISVAGD
WRQRSLQEAPGGWCFEYRNDHYPDCDDTAEALLALARVRGRFALEGRRQEALARGLAWLL
GMQNPDGGWAAFDRGCDKEVLTFIPFADHNAMIDPSTPDITSRSIRALLAAGLGPREAPV
RRAAGYLLRQQEEDGSWPGRWGANHIYGTGLSLRALGELASPAARDRSDALARALKRGRS
WLVRVQNGDGGWGESLRSYEHPTARGRGDSTASQTAWAMLGLSAAVRARPEPRESGVARA
ALDRAAAFLQERQREDGSWYDHWWTGVGFPGVFYLRYHGYAQYFPLAALAAYRRLRSGSR
R
>T2AY99|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWFGRWG
>A0A370GCQ0|squalene-hopene cyclase|EC 5.4.99.17|Gluconacetobacter liquefaciens|TrEMBL
MMVNATDTLERPSAGAADPVVPMIEIDQAVDSAHAALGRRQNDDGHWVFELEADATIPAE
YVLLEHYLDRIEPDLEARIGVYLRRIQGDHGGWPLYHGGRFDLSATVKAYFALKAIGDDI
DAPHMARARAAILDHGGAERSNVFTRFQLALFGEVPWHATPAMPVELMLLPRKALFSVWN
MSYWSRTVIAPLLVLAALRPRAVNPRDVHVPELFVTPPAQVRDWIRGPYRSALGRVFKYV
DKVVRPGERLIPEATRRRAIKAAVDFIEPRLNGVDGLGAIYPAMANSVMMYRALGVPDSD
PRAATAWESVRRLLVENGDEAYCQPCVSPIWDTGLAGHAMIEAASGPDGIRPHETKKKLA
AAAEWLRSRQILDVKGDWAINCPDVAPGGWAFQYNNDYYPDVDDTAVVGMLLHREGDPAH
HDAIERARQWILGMQSTNGGWGAFDIDNNMDFLNHIPFADHGALLDPPTADVTARCVSFL
AQLGHPEDRPVIERAVAYLRSDQEAEGCWFGRWGTNYIYGTWSVLCALNVAGVSHDDPAI
VRAVDWLRSVQREDGGWGEDCATFEGATPGIYTESLPSQTAWATLGLMAAGLRDDPAVAR
GMAYLARTQKEDGEWDEEPYNAVGFPKVFYLRYHGYRQFFPLMALSRYRNLESSNTRRVA
FGF
>R9W0A7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAQAVFARGTAGVPADDPRMEKAADWILPKQVRTKGDWEMKVKKGQPGGWYFEFN
NEFYPDVDDSAQVFLGLSKVDNPRDRYQRDVGQRAIDWIFAMQCRNGGWASFDKDNDKMM
FQYVPFADHNAMLDPPTVDITGRILEMLATYGYTRTDRRVERAISFVNEEQEPDGSWFGR
WGVNYIYGTLLVLRGLEAIGVCLHEPRIQQGAEWLRMVQNPDGGWGE
>A0A3P0MP91|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp9031|TrEMBL
MIRRMNKPAPSPWSALDAAIARGRDALMRLQQPDGSWCFELESDATITAEYILMTHFMDR
IDDARQEKMARYLRAIQRLDTHGGWDLYVDGDPDVSCSVKAYFALKAAGDSEHAPHMVRA
RDAILKLGGAARSNVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNVAIPELFVTPPDQERQYFPPARGMRRAFLALDRMVRHVEPL
LPKRLRQRAIRHAETWCAERMNGEDGLGGIFPPIVYSYQMMDVLGYPDDHPLRRDCENAL
EKLLVTRPDGSVYCQPCLSPVWDSAWSTMALEQARGVAVQESGTPASALDELDARIARAY
DWLAERQVNDLRGDWIENAPADTQPGGWAFQYANPYYPDIDDSAVVTAMLDRRGRTHRNV
DGSHPYAARVARALDWMRGLQSRNGGFAAFDADCDRLYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTQRADDRASLARAIDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALAGED
PSQPYIARALAWLRARQHADGGWGETNDSYSDPALAGTNAGESTSNCTAWALLAQMAFGD
GESDSVKRGIAYLQSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GAAAASGNRMPSAETTLPAIA
>A0A060A0Z7|squalene-hopene cyclase|EC 5.4.99.17|Acidithiobacillus caldus (strain ATCC 51756 / DSM 8584 / KU)|TrEMBL
MNPVVHNLTRPHRSAEPRPSALQRSIAAAQAALLQHQAADGHWCFEFEADCTIPAEYILM
MHYMDERDAALEAKMAAYLRRKQENHGGWSLYHGGHFDMSASVKAYFALKLAGDDPEAAH
MRRARSAILAHGGAERANVFTRITLALFGQVPWRAVPFIPVEILLFPRWFPMHIYKVASW
SRTVMVPLFILCSLKPQAKNPLGVHIRELFTRPPEDIDDYFAHALQGWVSRIFLWFDRLG
RALESWIPQALRRRAIARAEAWFIERLNGEDGLNGIFPAMVNAHEALALLGYAAEHPYRQ
QTRAALTKLVVERAGEAYCQPCVSPVWDTCLALHALLEADGDVSEAARRSMQWLLDRQIT
DAPGDWRERRPHLAGGGWAFQYANPYYPDLDDTAAVAWALARARRPEDRPAVERAANWLA
GMQSRNGGFGAYDVDNTYYYLNEIPFADHKALLDPPTADVSGRVLAFLAILDREQDAPVR
ARLIQYLLREQEPSGAWFGRWGTNYIYGTWSVLMGMAELRDPGAEVRDAMARAAHWLRSV
QQDDGGWGESNDSYADPGLAGLGQESTAAQTAWACLALMAAGDSDSESLRRGIQWLQRHQ
EQPGDWQDPYFNAPGFPRVFYLTYHGYKIYFPLWALARYRNITERHCA
>A0A5D3KDZ6|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium rifense|TrEMBL
MDSVNATSGEALELSIASATQGVLGFQQPDGHWVFELEADCTIPAEYVLLRHYLAEPVDT
ALEAKIGNYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDSVDAPHMVRAREAMH
ARGGAIHSNVFTRFMLAMFGVMTWRAVPVLPIEIMLLPFWSPFHINKISYWARTTMVPLM
VLAALKPRAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFLLFRALDGILRVVEPMFP
KSLRQRAIDAALVFTEERLNGEDGMGAIYPPMANIVMMYDALGKDENYPPRATTRRGLDK
LLVIKDDEAYCQPCVSPIWDTTLTAHALLEAGGDKAVPAAKQGLDWLIPKQELEVKGDWA
VKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGATGYDAAIDRGREWIEGMQ
SDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETAKTSKHVAD
GVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVPHTDPMMRKAAGWLASIQNQD
GGWGEDAVSYRLDYKGWEPAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIATQNEKG
LWDESRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRSTNSRVVGVGM
>A0A7X0HFH0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces candidus|TrEMBL
MTATTDGSTGAVDPGAAAASMTITAVTDPVPDAREAARGAMGRAVEHLLALQDVQGWWKG
DLETNVTMDAEDLLLRQFLGVQDEKTVRAAALFVRGEQRADGTWATFHGGPGDLSATVEA
YVALRLAGDLPEDPHMRRAATWVRARGGIAATRVFTRIWLALFGWWKWDDLPELPPELLF
LPTWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHIDPRRPSPPTRLAPPTG
WDGIFQRLDKALHVYRRFAPPALRRAAMRSAARWIVERQENDGCWGGIQPPAVYSLIALH
LLGYDLQHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPA
LVKAADWMLAEEVVRPGDWAVRRPDLPPGGWAFEFHNDNYPDIDDTAEVILALRRVAHPD
RERTEGAIARGVRWNLGMQSKNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGKAHHPRTRRGITWLLAEQEECGAWFGRWGVNYVYGTGSAVPALTAAGLPGSH
PAIRRAVAWLESVQNDDGGWGEDLRSYKDKSWAGRGASTPSQTAWALLALIAAGECDSKA
TERGVAWLVETQLPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYINGEPVFPA
ARP
>A0A7W8L457|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia youngii|TrEMBL
MNDLSQTQPLDAVLPEAADAAPNLAEAAVVANAPAVADALATATPSAMQTAGASPLDASI
TRATDAILAAQQPDGHWIYELEADATIPAEYVLLVHYLGETPNLELEQKIARYLRRIQLP
NGGWPLFTDGALDISASVKAYFALKMIGDPVDAEHMVRARDAILTHGGAEHANVFTRILL
ALFGVVSWRAVPMMPVEIMLLPMWFPFHLSKVSYWARTVIVPLLVLNAKRPLARNPRKVR
IDELFRGAPVNTGMSERAPHQHAGWFGFFRCVDTVLRAVDGLLPKASRERAIRAAVAFVD
ERLNGEDGLGAIFPAMANSVMMYDVLGYPADHPNRAIARKSLDKLLVIKDDEAYCQPCLS
PVWDTSLAAHALLETGEARAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYN
NAHYPDVDDTAVVVMAMHRSAALTKSDVDREAIARAREWVVGMQSSEGGWGAFEPENTQY
YLNNIPFSDHAALLDPPTADVSGRCLSMFAQIGELPQNSEPAQRAFDYMLQEQESDGSWY
GRWGLNYIYGTWTALCSLNAAGMAHDDPRMRRAVQWLVSIQNEDGGWGEGGESYKLDYRG
YERAPSTASQTAWALLGLMAAGEVDHDAVARGIDYLQREQREHGLWDETRFTATGFPRVF
YLRYHGYRKFFPLWALARFRHLKRNGLTRVTVGM
>A0A6M5JAA2|squalene-hopene cyclase|EC 5.4.99.17|Sphingomonas sp. AP4-R1|TrEMBL
MHGSLLSSSADRLAASDEAVSEAVAALAAAQRDDGHWVFELEADATIPAEYVLLRHYLAE
PEDLELEARIGRYLRRIQSAEHDGWPLYHGGAFDISATIKAYFALKMIGDDPAAPHMERA
RKAVLAAGGAEACNVFTRIQLALFGCGSWDAVPTMPPELIFAPRWLPVHLYKMSYWARTV
VVPLLVLAALKPLARNPRGVRVDELFSGSPAALKSQAAQKSWIWTAGYTGLDRLLKAGDG
LWPKGLRTRAINACRDWVVERLNGEDGLGAIYPAMANSVMMFDALGVPADDPKRAIARKS
VELLLVHREGETYCQPCVSPVWDTALAAHAMLEVGEPEAEAMADRALAWLKPLQVLDVEG
DWADERPGVRPGGWAFQYRNDHYPDLDDTAVVVMAMDRAAGRAAGGAAGDYGQAISRGIE
WTVGLQSKNGGWGAFDADNSHDHLNNLPFADHGALLDPPTADVSARVVSMLAQKGEPLES
PRMQAALGYLRAEQEPEGSWFGRWGVNFIYGTWSVLCALNAAGVDRADPMIAKAVDWLNA
IQNADGGWGESCDSYDLARVAHVAAPSTASQTAWALLGLMAVGEVGSPAVARGIEWLVRH
QEDDGLWGQEYYTGGGFPRVFYLRYHGYPKYFPLWALARYRNLVRSNDGAVKWGM
>A0A4R1DEE4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. KM273126|TrEMBL
MTATTDGSTGAPPPRAASASETETDIDTLGVAGVPDAAVRATARATDFLLSRQDAQGWWK
GDLETNVTMDAEDLLLRQFLGIRDDRTTKAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLSGDAPDAPHMAKASEWIRARGGIAASRVFTRIWLALFGWWKWEDLPELPPELI
YFPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPRDPNPSVPLAPAA
SWDGVFQRLDKVLHGYHKVALKPLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIAL
HLLGYDLQHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATTALVDAGLPADHP
QLVKAADWMLGEEIVRPGDWAVRRPGLPPGGWAFEFHNDNYPDIDDTAEVALALRRVKHP
DPERVNKAIARGVRWNLGMQSRNGAWGAFDVDNTSPFPNKLPFCDFGEVIDPPSADVTAH
VVEMLAVEGLAHDERTRRGIEWLLAEQEPNGSWFGRWGVNYVYGTGSVVPALVAAGLPAS
HPAIRRAVAWLEAVQNDDGGWGEDLRSYHDVAGWSGKGASTASQTAWALLALLGAGERES
KTVERGIEWLAGTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFT
DRSDSTDTTAAPVKGS
>A0A7U9E1Y6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces lividans 1326|TrEMBL
METRAPADGGPSRRTTCTLHEGEAMTATTDGSTGASLRPLAASASDTDITIPAAAAGVPE
AAARATRRATDFLLAKQDAEGWWKGDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIR
GEQREDGTWATFYGGPGELSTTIEAYVALRLAGDSPEAPHMARAAEWIRSRGGIASARVF
TRIWLALFGWWKWDDLPELPPELIYFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPA
PFPLDELHTDPARPNPPRPLAPVASWDGAFQRIDKALHAYRKVAPRRLRRAAMNSAARWI
IERQENDGCWGGIQPPAVYSVIALYLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEAC
QSPVWDTCLATIALADAGVPEDHPQLVKASDWMLGEQIVRPGDWSVKRPGLPPGGWAFEF
HNDNYPDIDDTAEVVLALRRVRHHDPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSA
FPNRLPFCDFGEVIDPPSADVTAHVVEMLAVEGLAHDPRTRRGIQWLLDAQEADGSWFGR
WGVNYVYGTGSVIPALTAAGLPTSHPAIRRAVRWLESVQNEDGGWGEDLRSYRYVREWSG
RGASTASQTGWALMALLAAGERDSKAVERGVAWLAATQREDGSWDEPYFTGTGFPWDFSI
NYNLYRQVFPLTALGRYVHGEPFAKKSRAADAPAEAAPAEVKGS
>A0A538KPI5|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MTLAPDRTATTLDRAVERATERLLELQHPEGWWVGELESNATMIAQHLFWHHFLGLRTPE
LDHKIANELLARQRDDGTWAIWFEGPPDLSTTIEAYTALKLAGADPGARAREYIRDEGGA
SRARVFTKCFLALLGHWPWQWIARMPPEVILLPPDGPFSVYNFSCWARQTVVPLSVVQAL
RPVRPAAIDLREIGARSGQTKPPPRPGPIRRVAFATAERWVRDRQEADGSWGGIQPPWVW
SIIMLAALGYGFEDETLRAAVEGWTGFTIDDGDRLRPEACQSPVWDTALAVLALLDAGVP
SAHPALRRAGDWLVGEEVTVSGDWAIRKPDLPPGGWAFEFENDLYPDVDDTAVVALALRG
LGRGAGAVDRGLAWTAGMQSRSGGWGAFDVDNEAHWLYKLPFCDFGKVTDEPTADVSAHA
LEALAAEPRYATEVGRGLDWLIGEQEKDGSWFGRWGVNHIYGTGAALPALAACGLTSDHP
AMRRAVTWLKTVQQPDGSFGENIRSYADPSWRGRGHPTPSQTAWALLGYVAAGEAGSDPA
NRAADWLCSEQLSNGDWQEDHYTGTGFPLDFMIRYHLYRLHFPLMALGRLRERLAA
>A0A538M154|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MASSAVEAPSRARVALELACERLLALQNEGGWWQGELQTNVTMDAEDMLLREFLGIRTED
ETRRSAEWIRSQQRADGTWANFYGGPGELSTTIEAYWALRLAGDAPDAEHMRAAASFIRQ
SGGLQGARVFTHVWLALFGLWPWEQVPALPPEVVLLPSWVPLNIYDFACWARQTIVALSL
VKAHRPSRRLPFDLAELHGSGRAAGGGRAPGGRAAWLARLDRALGAYERRPLPPLRRLAL
DRAERWIVRRQEADGSWGGIQPPWVYSLMALHLCGYPLEHPVMRRGLEGLEGFMYEDRDD
SRGVGAPAGPSRRLEACQSPVWDTALAIIALRDAGVAAEHPALVRAARWLLGEEVRGRGD
WSIARPRLEPGGWAFEFANVNYPDVDDTAEVVLGLRRVEGVASEAAIERARVWVEGMQTS
GGGWGAFDAENTRELVRELPFLDFGEVIDEPSADVTAHAVEMLAALGRREEPVTQGAVAW
LLEHQERGGSWFGRWGINHVYGTGAVVPALIAAGVDPAHESIRRAVRWLGEHQNDDGGWG
EDPRSYDDEKWIGRGASTASQTAWALLALHAAGERGELVQRGIRWLVETQRPDGGWNEPQ
YTGTGFPSDYYINYHLYRLAFPISALGRCLSEG
>A0A538C6I1|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MASSTLEAQRAAEVALELAREHLLDLQDDGGWWRGELQTNVTMDAEDMLLREFLGARRAD
ETERSAAWIRSQQREDGTWANFYGGPGDLSTTIEAYWALRLAGDPPDAPHMLQAADFIRR
RGGLNRARVFTHLWLALFGLWSWEDVPALPPEIILLPSAVPLNVYDFACWARQTIVALSV
VKAHRPNCELPFDLDELRVVSAAQAPAPRSALARLLALLDRGMRAYERHPLPWLRRRALE
RAERWIVERQEADGSWGGIQPPWVYSLMALKLQGYSLEHPVMRKGIEGIDGFMVEDEDDA
HGVGAPPGRSRRLEACQSPVWDTALAMIALSDAGLPGDHPAMQRAAAWLLEQEVRARGDW
VVARPQLAPGGWAFEFANVNYPDVDDTAEVVLALQRLGAAGSGDGAAGASAAASERAAAW
VRGMQTSDGGWGAFDAENTRTLVRELPFLDFGEVIDEPSADVTAHAVEMLAVLGRRDAPE
TRHGVRWLIERQERDGSWYGRWGVNHVYGTAAVVPALIAAGVEPSQECIVRAVRWLVERQ
NEDGGWGEDPRSYDEARWIGRGASTASQTAWALLALHAAGERSQSLTRGLEWLVGAQRPD
GGWDEPEYTGTGFPCDYYINYHLYRLVFPVMALGRCLSASR
>A0A538CEF5|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
FTRAFLALIGQWPWRRLAHVPVELILLPAGGPLSVYDFACWARQTMVALSVVEALRPVRS
SHIDLSEIGGLRRHAVGVAERWVRERQEADGSWGGIQPPWVWSLVMLAALGHGFEDETFA
RGLAGWERFMVRDGDRLRPEACQSPVWDTALAVLALRAAGVPAEDPRLQAAGDWLLREEV
TARGDWAVRRPALAPGGWAFEFDNDLYPDVDDAAVVVLALRELGIGDDAVRRGLDWLVGM
QSRNGGWGAFDVDNEALWLYKLPICDFGKVTDEPTADVTAHALEALGHAQGNGAPLEAGL
DWLLAEQERDGSWFGRWGVNHVYGTGAAVPALEACGLPPGHPAIRRALAWLDSVQQPSGA
FGEDIRSYADPSWRGRGAPTPSQTAWALLAYVSGGAAAGLSTRQAAEYLLRVQRPDGDWD
EQHYTGTGFPLDFMIRYHLYRLTFPLLALGRLRERLNG
>A0A8J7I9N6|squalene-hopene cyclase|EC 5.4.99.17|Dendronalium phyllosphericum CENA369|TrEMBL
MQTQDRVRVKKVAAAIAASQQHLLAMQYPAGYWWAELESNVTITAEVVLLHKIWGTDLAR
PLHKVEAYLRQEQRQHGGWELFYGDGGELSTSVEAYMALKLLGVPATDPAMKRARSFILQ
RGGISKTRIFTKLHLALIGCYDWRGIPSLPPWIMLLPPAFPINIYEMSSWARSSTVPLLI
VCDSKPIFLTDPTINLDELYAEGVEQVRWELPQSGDWTDLFLTLDRGFKLAESWNLVPFR
KEGIKAAEKWILERQEATGDWGGIIPAMLNSMLALRCLGYDANDPIVERGLQAIDNFAIE
TEDNYRVQPCVSPVWDTAWVMRALIESGIAPDDPAVVKAGEWLLEKQILDYGDWNIKNRQ
GKPGAWAFEFDNRFYPDVDDSAVVVMALHLAKLPNEKLKQAAIARALNWIASMQCKPGGW
AAFDLDNDQDWLNSIPYGDLKAMIDPNTADVTARVLEMLGASNLSINGQNLDRALAYLME
EQETEGCWFGRWGVNYIYGTSGVLSALALITPQKHQLSIERGVAWLVGCQNPDGGWGETC
RSYDDPSLKGKGNSTASQTAWALIGLIAALEGTGKLALEAIERGINYLLATQKPDGTWFE
ADFTGTGFPCHFYLKYHMYQQYFPLIALGRYQALIKDA
>A0A540P9D0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces ipomoeae|TrEMBL
MTATTDGSTGAPPPRAASASDTDHDTPAAAGLQDAAAHAMRRATDFLLARQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDEKTTQAAALHIRGEQRADGTWATFHGGPPELSTTIEAY
VALRLAGDDPDEPHMARASAWIRQRGGIAASRVFTRIWLALFGWWKWDDLPEMPPELIHF
PKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPGRPNPPKSLDPLGSW
EGAFQRLDKVLHGYHKVALKRLRKAAMNSAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLGHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQL
VKAADWMLGEEIVRPGDWSIRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHPDP
ERVEKAVRRGTRWSLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIEWLLAEQEPNGSWFGRWGVNYVYGTGSVVPALVAAGLPASHP
AIRRAVAWLETVQNDDGGWGEDLRSYRDAAEWGGKGASTASQTAWALLALLAAGERDAKA
TERGIEWLAQTQGEDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPAVLK
ATGS
>A0A5C8SFN2|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium sp. WL120|TrEMBL
MREAVNKVEALQRPKTQAISLDDVDHGVARATRALTALSHDDGHICFELEADATIPSEYI
LFHQFRDTKPPEGLEPKIGNYLRRTQEKHGGWALVHEGPFDMSCTVKAYFALKMIGDDIE
APHMRRAREAILSRGGAAQSNVFTRFILALYGEVPWAAVPVMPVEVMFLPKWFPFHLDKV
SYWARCVMVPLFVLQATKPLAKNPRGIGIGELFLTPPSSVRRWPGSPHATWPWTPIFGGI
DRILQKVEGHFPKRIRLRAMEKARAWVSERLNGEHGLGAIFPAMVNTVLMYEAMGYGPDH
PQVRVACDAIEKLVVVKAHEAYVQPCVSPVWDTALAGHALLEAGGTDAEGQARAGLDWLL
PRQVLDIAGDWAAAKPKVRPGGWAFQYANAHYPDLDDTAVVVMAMDRAMRQHGLVANMPD
YTASIARAREWVEGLQSKDGGWAAFDADNNHMYLNHIPFSDHGALLDPPTADVTARVVSM
LSQLGETRESSKALDRGVTYLLNDQEQDGSWYGRWGMNFIYGTWSVLCALNAAGVDPQSP
EIRRSVEWLIRIQNPDGGWGEDASSYKIDPAFEAGSSTASQTAWALLALMAAGECDDPAV
TRGINFLARTQGADGFWNEERYTATGFPRVFYLRYHGYPKFFPLWAMARYRNLKRGNSRQ
VAYGM
>I4I481|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa PCC 9809|TrEMBL
MNYLHSWSLEVVERKKMQIQDKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELESNVT
ITSEAILLHKIWKTDKNRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLL
GIPVNDPALEKAREFILAKGGISKTRIFTKMHLALIGCYDWLGVPSIPAWIMLLPENFPF
TIYEMSSWARGSTVPLLIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNNWSDVFLWL
DGLFKWTEKTDLVPFRQESLQAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVDD
PIVARGLKAVDNFAIQRDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAIIKAGQWLI
DQQILDYGDWAIKNKIGTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKGVMK
RAVNWMATMQCKAGGWGAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDV
KMEENRVKKALDYLEKEQEADGSWFGRWGVNYIYGTSGALSALAFLEPNQYRHQLQKGAN
WLSSCQNVDGGWGETCFSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKG
VNYLLVTQKENGTWDEDYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>F8EV08|squalene-hopene cyclase|EC 5.4.99.17|Zymomonas mobilis subsp. pomaceae (strain ATCC 29192 / DSM 22645 / JCM 10191 / CCUG 17912 / NBRC 13757 / NCIMB 11200 / NRRL B-4491 / Barker I)|TrEMBL
MTLSTSSVPNLSILPDNIEPVIEKAAQALLDTQKQDGHWVFELEADATIPAEYILLRHYL
GEPEDLELEAKIGRYLRRIQGDHGGWPLFYKGGFDISATVKAYFALKMIGDSPDEPHMQR
AREEILAHGGAITSNVFTRLQLALYGAIPWETVPQMPVEMMLLPDWFPIHINKMSYWART
VLVPLLVLQAVRPLAKNPRGILVDELFVPGATVPARADGKWVWKIGFGALDKVLHKAESF
WPKANRKKAIDACVNFVSERLNGEDGLGGIYPAIANSVMMYDALGYPEDHPERAIARKAV
EKLLVFNPEEQDSDDEIYCQPCLSPIWDTALAAHAMLEVGGDKAEKAAIDALNWLEPQQI
LDVKGDWAWQKPDLRPGGWAFQYNNAYYPDVDDTAVVVMAMDRAGKLPEIGSKFEESKSR
AIEWTLGMQSDNGGWGAFDANNTYYYLNNIPFADHGALLDPPTVDVSARCVSMLAQAGKT
LQDDDMKTAVHYLFQEQEKDGSWFGRWGVNYIYGTWSALCALNAADIPHDHLNIRRAVQW
LESIQNEDGGWGEDCDSYALDYKGYQPAVSTPSQTAWALLGLMAVGETDSTAVARGINWL
ANNQDEHGFWKEDYYSGGGFPRVFYLRYHGYSKYFPLWALARYRNLSRANQPKVAYGM
>A0A7X2KFQ0|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium HT1-32|TrEMBL
MNIISDVTASSQTPSISDPSLVDQTISEALADLERMQGDDGHWVFELEADVTIPAEYIFL
NHFLDTIDDEVEQKLANYIRRQQSVVHGGWPLYHDGEFNISASVKGYFALKLVGDDPDEP
HMQRARQAILDYGGAERANVFTRFALALFNQAPWHAVPVMRPEAMLLPRWSPFHIEKVSY
WSRTVMIPMFVLYSLRAQAANPRGVKIDELFTRPPFEINDYNSNPTGSGWGEFFLKLDKV
VRFAEPMFPKLLERRGVQKCLNFVKERLNGEDGLGAIFPAMANTVMMYHTLGYPADHPDF
VIARKSIDNLLILKEDEGYCQPCVSPIWDTALAAHAVAEASAATDGSGDPDLSTARSACD
WLVKRQITEVFGDYAWKKPDLKPGGWAFQYNNDHYPDVDDTAVVAMAMDRVDPERYADAI
SKATDWIIGMQSENGGWGAFDIDNTHYVLNNIPFADHGALLDPPTSDVTARCISMLAQLG
YDRSHEVVARGVDYLKSEQEPDGSWFGRWGTNYIYGTWSVLCAINAAGEDMQSDYVRRSV
AWLESKQREDGGWGEDGATYFDEQRGLAKASTASQTAWAVLGLMAAGEVDSPAVDRGIAF
LLRADREGTNWKEEWFTAVGFPKIFYLRYHGYPKFFPLWALARYRNLKTGNAKLPLTGM
>A0A5N9F088|squalene-hopene cyclase|EC 5.4.99.17|SAR202 cluster bacterium|TrEMBL
MAVEPKNTEVNQAADQAVRRSQDYFRRTQYQEGYWWGELESNPTMEAEYLMLCHFTGRHD
KERWRKVCNYILSKQRDDGSWGQYYEAPGDVSTSVECYFALKLAGHSPDSEPLQKARDFI
LSKGGIPKVRVFTKIWLALFGQWDWKGTPNMPPEMIFLPSWAPFNIYEFASWARATIVPM
LIILTHRPYCPVPESADIDELYPGGREGTDYRLPKPTGGFGWAKTLHWTDKLVGLYQRLP
VHPLRGRAERKIMQWVLEHQEADGSWAGIQPPWVYSLIALHTMGYGPEHEAVNKGFQGFE
VFALEDDEKCNVQACISPVWDTCIAQLALLESGVAPDDPMVQSSARWLMDKQIFAGGDWQ
VRAKDTRPGGWSFEFDNLAYPDIDDASIVVMALERVRLPEAEEPRRADSIKRGVEWVAGM
QCKNGGWAAFDKDNNKKYLTKIPFSDFGETLDPPSVDVTAHLLEMYGRLGYTREEQAVDR
GFEYVIGEQEENGSWFGRWGVNYVYGAGAVLPALEAIGEDMSQPYIRRAVDWIVAHQNKD
GGWGESCGSYVDPTLRGVGPSTASQTAWALLGLVAAGEHGCQATHQGLLYLAETQQEDGA
WDEPYFTGTGFPGYGVGERLKTLPDYGETSYQGLDMPAGFMINYHLYRNYWPLLALGRYS
QAAASSRTRGHRQDSYDLSKNRGRTPNLI
>A0A7K2Z4T7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID3343|TrEMBL
MTVTVQSGVEDVDDDKVRDALAKAVAHLMELQDDAGWWKGELETNVTMDAEDLLFREFLG
IRTEEQTQASARWIRANQREDGTWATFKDGPADLSVTIEAYVALKLAGHDPGAKHMTAAA
EFIREGGGIANARVFTRFWLAFFGWYSWDDLPVLPPEIVFLPKWFPLNVYDFACWARQTI
VPLTIVSSLRPVRPAPFPLAELRPTRDVPGRKDADDPWSKVFRALDAVLHQYQKHPVRPL
RKTAMRKAAQWIIERQEADGGWGGIQPPWVYSLIALRLMGYPLNHPVMAQGIKGLDGFTI
VDTDEDGELRRRFEACQSPVWDTGLTLVALRDAGVPAADPRVVKAAEWLMDEEIREIGDW
AVRRPDLEPGGWAFEFANDWYPDTDDTAEIVMALRYTDHPDGARKAAVLDRAERWTAGMR
SKDGGWGAFDADNVSVLPLKLPFSDFGAVTDPPSADVTAHIVEMLADGGPRYSSYVVDGV
KWLMEHQESDGSWFGRWGANYVYGTGAVVPALVTAGVDPRHSAIRRAVRWLETKQNPDGG
WGEDLRSYADPEGWSGRGESTASQTAWALLALHAAGEFGEIAQRGITWLTDRQNASGGWD
EPQFTGTGFPGDFYIKYHMYRLVFPVMALGRYAETTG
>A0A6G0FH43|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SS1-1|TrEMBL
MTATTDGSTGAALPPRAAAASEIHSETPLATGAHEAAERAARRATDFLLARQDPEGWWKG
DLETNVTMDAEDLLLRQFLGIRDEETTRAAALFIRGEQRDDGTWATFYGGPGELSTTIEA
YVALRLAGDAPDAPHMAKASAWIRARGGIAEARVFTRIWLALFGWWKWEDLPELPPELIY
FPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPANPNPPKPLAPVAS
WDGAFQRLDKALHQLRKVVPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSIIALH
LLGYDLKHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALVDAGVPADHPQ
LVKAADWMLGEEIVRPGDWSVRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHD
AERMERAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGLAHDPRTRRGIAWLLAEQEPDGSWFGRWGVNYLYGTGSVVPALTAAGFPGSH
PAIRRAVAWLESVQNDDGGWGEDLRSYKYAKEWSGRGASTASQTAWALMALLAAGEKDSK
AVERGIEWLAATQRPDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGEPFAG
KATATATTPAADAEGSG
>A0A7C2JVA8|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MSVSAPRALDKPEDRVDATIGKAIAWLDREQTPEGFWVGMLESNYCMEAEWLLAMHFLGY
RHPREQDLVATLLNAQRPDGSWEAYYDAPQGDINGTVECYAALRSVGFEPDDEPLVRARR
WIFDHGGLKGIRVFTRYWLALLGEWPWSATPNLPPEVIANPRWFPFNIYNFASWARATLL
PLAVLSARRAVRPLPPERRLDELFPEGRDRMDYSLPRRGPWLSWRRLFLLSDRVLHWYQQ
VGFTPFRETAINACLGWIVRHQDSDGAWGGIQPPWIYSLMALNVEGYELDHPVMAAGLAA
LDSHWSYERGGTLHIQASESPVWDTLLTLLAMQDCEREFTPSMTRALDWVLENEVRYRGD
WAKKVKGVEPSGWAFERANLHYPDIDDTAVALIVLARLPLELRGEPRIRAAIDRALGWTL
AMQSTNGGWAAFDKDNDRLIITKIPFCDFGEALDPPSADVTAHVLEALGLLGFERKHPAV
QRGLEFLRREQETDGSWFGRWGVNHIYGTAAVLPALAAIGEDMTQPYVRAAADWLVAHQN
ADGGWGETCASYMDDKLRGRGTSTASQTGWALLALVAANDRQHERAIRRGIGFLLDSQRD
DGTWDEPYYTGTGFPGYGFGARIDFRDEKTRERIAQGIELQRGFMINYNLYRHYFPLMAL
GRARRFLAERTS
>A0A6L8EMB7|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
EQSTATITDSAFGELLSARLLQQEQVNLPVPQTDPLARTLVQSGTALLERQYRAGYWRFD
VEADTTIPAEYILFQHLMGTVDKEREQRLADYIFSRQLPDGSWPLYEGGAGNISATVKAY
FALKTVGCDPAGEAMRRACAWVRNNGGAERVNVFTRILLATFGQVPWRTVPAMPAEIIWM
PGWWFFSLEKVSYWSRCVIVPLLLIFSFRPVQRGTDIRELFREDPESLNHIDSYLPGICV
ENCFILLERLLKLLDPLVPGFIRRLSMRRLEAWMRERMRGEGGIGAIFPAMANAVYALKL
LGHDATDPDLKRGLQAIEDLVIEEEAQTYVQPCVSPIWDTCLSLSALSEAGLQPDNEAVK
PATDWLFDKQVFTRGDWTDKAPDLECGGWAFQFENDFYPDVDDTSMVVMALLRAGAHYHP
DKKKRIAQAVNWIIGMQNTDGGWGAFDIDNHHEYLNKIPFADHKALVDPSTADLAGRCIE
MLAMLGYDKTFPPVARAVDYLQRTQEPSGAWFGRWGVNYIYGTWAVLVGLGALGEDPNQP
WLRKAVKWLKDIQNSDGGWGEGCDSYSDPALAGSGESTASQTAWALLGLMAMGETESEEV
EKGINYLLRNFDGAKGWKETAYTGTGFPRVFYLRYHGYSHYFPVWALGVYARYRQGLETR
QDALVREGPVDLGVLPALNSKHYRSRFPASA
>A0A534BM59|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MSRKAGTSAALAGTEGLLRADAPARKLPGEKLSPLEYAIAAARDELIRLQHPDGSWELEL
EADCTIPAEYIMMMHFLGELDSALEAKLAAYLRQRQAGYGGWPLYHGGAFDMSCSVKVYF
ALKLAGDDPESPHMARARAAILERGGAASCNVFTRIALALFGQLPWRGVPYIPVEIVLLP
CWFPFNIHRVSYWSRTVMVPLLILCTLKPRARNPRNVDIRELFTTPPSQERRYFRRPLGG
CAALARAFFCLDRLARSLDGLIPRALREHALERAEAWMLERLNGEDGLGAIFPAMVNALE
ALSVRGYSPDHPHRRGAKRALEKLLVEDYSSAYCQPCASTLWDTALASLAMQEEGSAGAR
AAALRGLEWLEPRQLLDDPGDWRTRRPHLPGGGWAFQRANSYYPDLDDTAAVAWSMHRST
DPGRFSFALSRALDWLVGMQSENGGFASFDVDNTSYYLNEIPFADHGALLDPPTSDVTAR
VVTALARVGRPEDRVALTRAIDYLRREQEANGSWFGRWGTNYVYGTWSVLAAFAQARIGP
DDPAVERAVSWLESRQNPDGGWGESNDSYEPGRAGASAPSTPHQSAWAVLALIAAREAGS
DAVRRGIEYLLRTQRPDGLWSDPSFTAPGFPRVFYLRYHGYCAYFPLWALAAYRNSTAAG
PGTVH
>A0A523L524|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MAVNATDTVQTKPQLDDAIARATHWLDEEQDPEGFWVGMLESNSCMEAEWLLLMHFLDYT
HPRKQDLVNSILNAQRSDGAWESYYEAPSGDINSTVECYAALKAVGMSADDEPLVKAREW
IFAHGGLSSIRVFTRYWLALLGEWPWDKTPNLPPEVIANPRWFPFNIYNFASWARATLLP
LAVLSARRAVRPLPIESRLDELFPDGRERMNYKLPRRGRAFGWRRLFLFSNHIIHWYQRI
GLTPGRETAIKACVEWIVRHQDSDGAWGGIQPPWVYSLMALNVENYSLSHPVMAKGLGAL
DSHWSYERDGTLHIQASESPVWDTLLALLAMQNCDRPFNTGMDNALEWLLDKQVTDFVGD
WGQKIKRVEPGGWPFERANLHYPDVDDAAVALIVLAQLPEPQRSSARVQTAIERGRQWIL
ALQCRKGGWAAFDKDNDKLIITKIPFCDFGEALDPPSADVTGHVLEAFGLLGMSREDLAV
KRAYQYLLTEQETDGSWFGRWGVNHIYGTAAVLPGLAAIGDDMASPHVRRAVHWIIEHQN
TNGGWGETCASYMDEKLRGRGPSTASQTAWAIMALVAADHRSSDAAILRGLDYLLITQRR
DGTWDEPYYTGTGFPGYGFGGRLDFRDKDTKQRIAQGTELQRGFMINYNLYRHYFPLMAM
GRARARPAGASAR
>A0A7W8V4U4|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia atlantica|TrEMBL
MNDLSQTQPLDAVLPEAADAASNLAEAAVVANAPAVADALATATPSPMQSVGASPLDASI
TRATDAILAAQQPDGHWIYELEADATIPAEYVLLVHYLGETPNLELEQKIARYLRRIQLP
NGGWPLFTDGALDISASVKAYFALKMIGDPVDAEHMVRARDAILAHGGAEHANVFTRILL
ALFGVVSWRAVPMMPVEIMLLPMWFPFHLSKVSYWARTVIVPLLVLNAKRPLARNPRKVR
IDELFRGAPVNTGMNERAPHQHAGWFGFFRCVDTVLRAVDGLLPKASRERAIRAAVAFVD
ERLNGEDGLGAIFPAMANSVMMYDVLGYPADHPNRAIARKSLDKLLVIKDDEAYCQPCLS
PVWDTSLAAHALLETGEARAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYN
NAHYPDVDDTAVVVMAMHRSAALTKSDVDREAIARAREWVVGMQSSEGGWGAFEPENTQY
YLNNIPFSDHAALLDPPTADVSGRCLSMFAQIGELPQNSEPAQRAFDYMLQEQESDGSWY
GRWGLNYIYGTWTALCSLNAAGMSHDDPRMRRAVQWLVSIQNEDGGWGEGGESYKLDYRG
YERAPSTASQTAWALLGLMAAGEVDHDAVARGIDYLQREQREHGLWDETRFTATGFPRVF
YLRYHGYRKFFPLWALARFRHLKRNGLTRVTVGM
>A0A5B8JDZ8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces qinzhouensis|TrEMBL
MTATTDGSGGPVRARAAADSETASAPAPAGRPGERTAADERTGPARRAVARAVDHLLARQ
DAEGWWKGDLETNVTMDAEDLLLRQFLGIGDRTVTEASARFIRGRQRADGTWATFYGGPG
ELSATVEAYVALRLAGDLPGDPHMARAAAWVREQGGIAATRVFTRIWLALFGWWRWEDLP
VVPPELIFLPKWFPLNIYDFGCWARQTIVPLTVVSARRPVRPAPFGLDELHTDPLAPNPP
RPLAPAASWEGFFQRADRALHRYHRVAPRRVREAAVAAASRWIVERQENDGCWGGIQPPA
VYSLIALHLLGYDLGHPVMRAGIESLDRFAIWEKTETGAPVRMIEACQSPVWDTCLATVA
LADAGLAPDHPALVRAADWMLGEEIVRPGDWAVRRPGLAPGGWAFEFHNDNYPDIDDTAE
VMLALRRVAHPEPARIEAAVARAGRWTLGMQSRDGGWGAFDADNTSPFPNRLPFCDFGEV
IDPPSADVTAHVLEMLAYEGRAHTPRARRAIDWLLTHQEPGGAWFGRWGVNYIYGTGSVV
PALVAAGIPAAHPALRRAVDWLRSVQNPDGGWGEDLRSYDHGAWAGQGSSTPSQTAWALL
ALLAAGERESECAERGVRWLVAAQREDGGWDEPYFTGTGFPWDFSINYHLYRQVFPLTAL
GRYVHGEPPVGGVPRAGKPRTGALPARKGS
>A0A8J7EE89|squalene-hopene cyclase|EC 5.4.99.17|Nodosilinea sp. LEGE 06152|TrEMBL
MQTQEPQQLTGVDRAIAAAQNYLLALQHPDGYWWAELESNVTITAEIILLHKIWGTDGGR
PLAKAERYLRSHQRPHGGWELFHGDGGDLSTSVEAYMALRVLGVPASDPALLRAKDFILQ
RGGISKTRIFTKLHLALIGCYDWRGLPSLPAWVMLLESPSPFTIYELSSWARGSTVPLLV
VFDQKPVYVIEPAVTLDELYAEGVANVRWELPKAGDWSDIFVWLDGAFKFAESINFTPFR
DEGIRKAEQWILERQEATGDWGGIIPAMLNSMLALRCLGYDVNDPVVRRGLRAIDNFAVE
TDDTYWVQACVSPVWDTALGMRSLTDSGLAPDHPSLVRAGEWLLEKQILDYGDWIVKNPQ
GKPGGWAFEFDNRFYPDVDDTAVVAMALQDVTLPDEALKREAIARAVRWVATMQCKTGGW
AAFDINNDQEWINAIPYGDLKAMIDPSTADITARVLEMHGRLCREPDLAARYASDLTAQR
LEQGLAFLLNEQEADGSWFGRWGVNYLYGTSGALSALALIAPERCQGAIARGANWLVSCQ
NPDGGWGETCRSYDDPALKGQGPSTPSQTAWALLGLIDAADSGVAAEPAIKRGIHYLLTT
QTAEGTWDEQEFTGTGFPRHFYIRYHLYRHHFPLMALGRYRARA
>A0A484H4M9|squalene-hopene cyclase|EC 5.4.99.17|invertebrate metagenome|TrEMBL
MRTLLCQQAVQLRKQTLSLFLVAMETIMRDFSMPLVEKLDQVIEQAAAALIRYQTPDGPF
IFELEADATIPAEYILLNHYLGTPHDSLERKLAHYLRAIQGGDGGWPLYHQGEANVSASV
KAYYALKLVGDSALAPHMCRARDRILALGGAARCNVFTRITLALFGQVPWRAVPVMRVEA
MLLPRWFPLHIDKVSYWSRTVMVPLLILYSLKPQARNPRQIGITELFSVPADQVRCYHSN
PTGQVLGDIFVRLDRLAQLCEPLLPRFIERKAITRALDFVVERLNGEEGLGGIFPAMANA
IMAFEALGYPLDHPWCATTRRALDKLLVIEDEKAYCQPCLSPVWDTALACHALMETGVTG
EAAVISQALMWLKGRQVLDVAGDWAVQRPHVRPGGWAFQYANPHYPDVDDTAVAVMILDR
ARRDLPPGQEQDSHARSIARGGEWVIGMQCSNGGWAAFNAENEHYHLNHLPFADHGALLD
PPTADVSARCLGMLGQLDSAHPAMALGIDWLRRQQELDGSWFGRWGTNYIYGTWSALSAL
AAAGENTAAPHVHRAVAYLKGRQRFDGGWGEDCASYWMDRKTEVKGSTPSQTAWALLGLM
AAGEVNSSAVEHGIRYLLAAPRTGAKWHEELFTAVGFPRVFYLRYHGYSAYFPLWALARY
RRLKYRSDPGMLLGL
>A0A516J723|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium cosmicum|TrEMBL
MDSVNATSREAQESRILESKVLESSIASATQGVIGFQQPDGHWVFELEADCTIPAEYILL
RHYLAEPVDTVLEAKIGNYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDSVDAP
HMVRAREAMHARGGAINSNVFTRFMLAMFGVTTWRAVPVLPIEIVLLPFWSPFHLNKISY
WARTTMVPLMVLAALKPRAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFVLFRALDG
ILRVVEPMFPKSLRKRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKDENYPP
RAITRRGIDKLLVIGDDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAARQGLDWLIPK
QELEVKGDWAVKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGVAGYDAAID
RGREWIEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGE
TEKTSKHVAAGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGIRHDDPMMRKAA
AWLASIQNKDGGWGEDAVSYRLDYKGWEAAPSTASQTAWALLALMAAGEVDHPAVARGVE
YLIATQNKKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A4Q1QKK8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sioyaensis|TrEMBL
MTATTDGSTGALPPRAPSASDATAGKTAASARVRSALGGDTADAARRATARATDHLLSAQ
DPAGWWKGDLETNVTMDAEDLLLRQFLGLQDPELTEAAARYIRGEQCPDGTWATFYGGPG
ELSTTIEAYVALRLAGDAPDAPHMARASAWVREQGGVAAARVFTRIWLALFGWWKWDDLP
QLPPELLYFPKWFPLNIYDFGCWARQTIVPLTIVSATRPVRPAPFALDELHTDPRRPNPP
RPLAPAVSWDGLFQRLDKALHLYHKVAFRRLRRAAMRSAARWIIERQENDGCWGGIQPPA
VYSVIALHLLGYDLDHPVLRTGLASLDRFAVRRADGARMIEACQSPVWDTCLATISLADA
GVPADHPQLVKAAEWILAEQIDRPGDWSVKRPQLPSGGWAFEFENDNYPDIDDTAEVVLA
LRRVKHPDPQRVEAAVRRAVRWNLGMQSRDGGWGAFDVDNTSPLPNRLPFCDFGEVIDPP
SADVTAHVVEMLADVGRTHDPRTRRGIAWLLAEQDPCGAWFGRWGTNYLYGTGSVLPALA
AAGIPRSHPAVRRAVRWLEGVQNDDGGWGEDQRSYQDKEQWAGRGASTASQTAWALMALL
AAGERDGEAVRRGVRWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRY
LNGGPAVAPVGS
>A0A7W8T749|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia sp. MM5384-R2|TrEMBL
MNDLSHTQPLDAALPEAADAAPDLAEAAVVANAPAVADALATATPAPVQGASALDASITR
ATDAILAAQQPDGHWVYELEADATIPAEYVLLVHYLGETPNLELEQKIARYLRRIQLPDG
GWPLFTDGALDISASVKAYFALKMIGDPVDAEHMVRARDAILAHGGAEHVNVFTRILLAL
FGVVSWRAVPMMPVEIMLLPVWFPFHLSKVSYWARTVIVPLLVLNAKRPLARNPRKVRID
ELFRGAPVNTGMNERAPHQHAGWFGLFRCVDSVLRAVDGLLPKATRERAIRAAVAFVDER
LNGEDGLGAIFPAMANSVMMYDVLGYPADHPHRAIARKSLDKLLLIKDDEAYCQPCLSPV
WDTSLAAHALLETGEARAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYNNA
HFPDVDDTAVVAMAMHRSAALTQSDVDREAIARAREWVVGMQSSDGGWGAFEPENTQYYL
NNIPFSDHGALLDPPTADVSGRCLSMFAQIGELPQSSEPARRAFDYMLQEQESDGSWYGR
WGLNYIYGTWTALCSLNAAGMPHDDPRMRRAVQWLVSIQNDDGGWGEGGESYKLDYRGYE
RAPSTASQTAWALLGLMAAGEVDHEAVARGIDYLQREQREHGLWDETRFTATGFPRVFYL
RYHGYRKFFPLWALARFRHLKRNGLTRVTVGM
>A0A7W9SMH1|squalene-hopene cyclase|EC 5.4.99.17|Armatimonas rosea|TrEMBL
MSAPTAQELLLAERNDTGHWIGCLSSSALSTATSSFTLALYLKHHPTLPSAEREKLAPLV
DSGARWLTETQNPDGGWGDTTRSPSNISTTTLCWAALSFFQPEASPVITAAEAWLKNAAG
ALTPEHLAATIAARYGKDRTFSVPILTMCALAGRLGDGEAAWRVIPRLPFELAALPHTWF
QWLQLPVVSYALPALIAIGQVGHHLHPTGNPILRALRERARPKTLALLQAIQPEGGGFLE
AAPLTSFVTMSLIASGKRDSPVVAAGLDFLVRSARPDGSWPIDTNLATWVTTLAINALSA
SGPLPLTTDEKDTLRTWLLNQQYRVEHPYTHAAPGGWAWTDLPGGVPDADDTAGALIALH
RLGPEAPGVAAAAQLGVTWLLELQNRDGGMPTFCRGWGALPFDRSGADLTAHALLAWSTW
REQVPTPLPQRIDQATKKALVYLARQQRPDGSWVPLWFGNHAAPHDENPTYGTARVLLAL
YSLPESSTPAQGCRERGLTWLLKAQSPNGGWGGDQGVGPSLEETGLALQALAQARRATGE
SSALDTALAQGREWVRKHLQEGHHHTPAPIGFYFANLWYFERLYPLLFSAGATAGTEL
>A0A4Q5KZU1|squalene-hopene cyclase|EC 5.4.99.17|Methylococcaceae bacterium FWC3|TrEMBL
MFKDAIDTFDSDFAATAAASESPLDRSVREARDALLQMQHKDGFWVFELEADCTIPSEYI
LMMHYMDEIDVGLQAKIAHFLRGRQQQDGSYPLFTGGPGDISCTVKVYYALKCAGDSIDA
PHMVKARGWILEQGGAARANVFTRIMLAMFEQIPWRGVPFIPVEIMLLPKWFPFHLDKVS
YWSRTVMVPLFILCSYKVKARNPNGVHVRELFTVDPNEERNYFSHVKTPLGKAILALERF
GRSLEPLIPRSMRQRATQKALDWFSERLNGVDGLGAIFPAMVNAYEALDYLGVPPEDERR
RLAKEALERLLVIDGDTAYCQPCVSPVWDTALTSLALQEANRLDPDAETSAALIRGLQWL
ASKQVTDAPGDWRVNRPGLEGGGWAFQYENPYYPDVDDSAVVAQAMLQAEDPQFDRTLEL
ATTWIAGMQSKNGGFGAFDADNTHYYLNHIPFADHGALLDPPTADVSGRCAMFLANTLEQ
RPEVRPVVDACIEYLRREQEPDGSWFGRWGTNYIYGTWSVLLGYEKAGIPKDDPSVRKAV
AWLKSVQREDGGWGEDNYSYHDTRLSGRFHTSTAFQTGLALIALMAAGEADSDEVRAGVD
FLLRQQQADGFWADGCFTAPGFPKVFYLKYHGYDKFFPLWALARYRNETRG
>A0A7X3I5N8|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium sp. 2A|TrEMBL
MREALSKVEPLQRSKTQGISLDDVERGVAQATRALTALAHEDGHICFELEADATIPSEYI
LFHQFRGTQIRDGLEAKIGHYLRRTQGPHGGWALVHEGPFDMSCTVKAYFALKMIGDDIE
APHMRRAREAILARGGAANANVFTRFLLALYGEVPWRAVPVMPVEVMFLPKWFPFHLDKI
SYWARTTVVPLFVLQATKPRARNPRGISVQELFVTPPESVRSWPGSPHATWPWTPIFGFI
DRILQLVEDHMPRKSRQRAMEKARAWVSERLNGEDGLGAIFPAMVNSVLMYEVMGYRPDH
PQVRVACDAIEKLVVEKADEAYVQPCVSPVWDTALASHALLEAGGPEAEAQARRGLDWLK
PRQVLDIVGDWAARKPKVRPGGWAFQYANAHYPDLDDTAVVVMAMDRAMHQHGLVAGMPD
YKASIARAREWVEGLQSEDGGWAAFDADNNHMYLNHIPFSDHGALLDPPTADVTARVVGM
LAQLGETRETSRALDRGVNYLLNDQEEDGSWYGRWGMNFIYGTWSVLCALNAAGVDPADP
RIQKAVSWLIRIQNPDGGWGEDASSYKIDPAFEPGSSTASQTAWALLALMAAGAVDDPAV
TRGINFLTRTQGADGFWKEERYTATGFPRVFYLRYHGYPKFFPLWAMARYRNLKRTNSRR
VQFGM
>A0A7X3QGJ4|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
MQGAQAAAGSASGLDVCIDRSVRHLLSLQAEDGYWWAELESNATMAAEHLLLERFLGTTE
EEREQGIVRYLLGLQCEDGSWPVYWGGPGDVSISTEAYFALKLAGVDPESEEMKRAREFI
RSRGGVGATRIFTKLWLSLFGQFDWAALPAMPPESILMPVASPLNIYMFASWARATIVAI
LVVWAYRPVVPIPDYAHVDELYLDPADRRSIPLRRDRQPFTWRNAFLAIDRVLHAHERLP
WKPLRDFSLKECERWIIEHQEADGTWGVIQPPSVYSLIALRAHGYSMDHPVMQKGLNGFL
GDFALRRGNTFSVQPCLSPVWDTALAVTGLREAGVPADDEALVQAGRWLLAHEVQSLGDW
ALTVPGIEPGGFPFEFSNELYPDTDDTAEVLIALRLLDLRGKDGPFHRSKVWLRAMQSTN
GGWGAFDRDNDDEFVSRIPFADFGATFDPPTEDVTAHILEAFALDGTPPSDEMMDRALDY
LWDTQEPDGSWWGRWGVNYLYGLGAAVPALVAAGVDPADPRLRRAVRWLEHHQQPDGGWG
ESCATYEDPSLRGQGPSTASQTAWALLALLAVEPPDHPATVRGIDYLVRTQTDDGEWIEP
HFTGTGFPRDFMLKYHLYSNYWPLWALGRYRRLRDGNPIHLPETDPLG
>A0A2X2M135|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces griseus|TrEMBL
MTATTDGSTGAANPSEATAHDPTDTTTAADDLTVAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLSIQDPETTRAAALFIRGEQLGDGTWNTFYGGPGDLSATIEAY
VALRLAGDRPDEPHMARAAGWIRDQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPDHPNPPRKLAPPTSW
DGLFQRLDKGLHLYHKVAPRPLRRVAMNLAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMKAGLASLDRFAVRREDGARMIEACQSPVWDTCLATIALADAGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARLQAAIDRGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLASHPRTREGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALITAGLPAGHP
AIRRAVAWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDTRPV
ARGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFADRA
MAAEGA
>A0A417YZE7|squalene-hopene cyclase|EC 5.4.99.17|Neobacillus notoginsengisoli|TrEMBL
MEDVQNGIDTLIEQLKQSQSPKGSWDFPFETGIATDCYMIILLKTLEIDDDNLIRGLAER
ILSRQEKNGAWKLFFDEGEGNLTATLEAYYALLFSGFVQKNDGRLRAARRFIQRSGGIEQ
AHMFTKIMLALTGQMKWPPFFPIPLEMILLPASFPLNFYSFSEFGRANLAPIMILADRKF
QLRAVGSPDLAGELKGREKDGIEWFRDDGAWRGLESFFAKSIKNLLGLPDELHKLATEKT
KNYMLDRIEPDGTFFGYFSSTFLMIFALLSLGFKQTDPVIAAAVEGLKGMKCEIDGFPHM
QYTTATVWNTSLISYALQEAGVSADDPVVEKANRYLLGHQHYKYGDWAIHNPYAFPGGWG
FADSNTIHPDVDDSTASLRAIAGSVQGDPNYQHAWERGTQWVLSMQNKDGGWPAFEKNTD
SRLLSLFPIQKASFLLADPSSADLTGRTLEFLCNETNLDRNHPSVKAGVEWLLKNQEKDG
SWYGRWGICYIYGTWAAVTGLRAAGVVPGHHAIERAVDWLKGIQNSDGGWGESCRSDSAE
KYIPLGASTLTDTAWAVDALIAATGRPTKEIHAGIKYLLDNLDQQNWTTRYPKGQGMAGD
FYIHYHSYNHFFPLLTLAHYKKLG
>A0A6G4Y4Z4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. 196(2019)|TrEMBL
MTATTDGPAGAAELSATTAGHPDRTTLAPDEVLAAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPSDLSATIEAY
VALRLAGDAPDAPHMARAASWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFL
PSWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPARPNPSRKLAPAASW
DGLFQRLDKGLHLYHKIAPRPLRRIAMNVAARWIVERQENDGCWGGIQPPAVYSLIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMVEACQSPVWDTCLATIALVDGGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARVEAAIERGVRWNLGMQSRNGAWGAFDADNTSSFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGRARHPRTRRGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALIAAGLPAAHP
SVRRAVEWLESVQNDDGGWGEDLRSYREEKWIGHGESTASQTAWALLALLAAGRRDSVAV
TRGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRT
GAAQGA
>A0A5C2M7M6|squalene-hopene cyclase|EC 5.4.99.17|Thermosynechococcus sp. CL-1|TrEMBL
MQTQIAAAIDPKQLQQAIRASQDFLFSQQYAEGYWWAELESNVTMTAEVILLHKIWGTEQ
RLPLAKAEQYLRNHQRDHGGWELFYGDGGDLSTSVEAYMGLRLLGVPATDPALVKARQFI
LARGGISKTRIFTKLHLALIGCYDWRGIPSLPPWIMLLPEGSPFTIYEMSSWARSSTVPL
LIVMDRKPVYAMDPPITLDELYAEGRANVIWELPRQGDWSDVFIGLDRVFKLFEILNINP
LREQGLKAAEEWVLERQEASGDWGGIIPAMLNSLLALRALDYAVDDPIVQRGMAAVDRFA
IETETEYRVQPCVSPVWDTALVMRAMVDSGVAPDHPALVKAGEWLLSKQILDYGDWHVKN
KKGQPGGWAFEFENRFYPDVDDTAVVVMALHAVTLPDENLKRRAIERAVAWIASMQCRPG
GWAAFDVDNDQDWLNAIPYGDLKAMIDPNTADVTARVLEMVGRCQLAFDSGALDRALAYL
RNEQEPEGCWFGRWGVNYLYGTSGVLAALSLVAPRYDRWRIRRAAAWLVQCQNADGGWGE
TCWSYNDPSLKGKGDSTASQTAWAIIGLLAAGDATGDYATKAIEKGMAYLLQTQRADGTW
HEDYFTGTGFPCHFYLKYHYYQQHFPLTALGRYARWRGLLANEKKSG
>A0A7K3DPQ9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5785|TrEMBL
MTATTDGSTGAAAPEAPSATTAPLTEPNPPEAGTRAAAGRAIQRATDFLLARQDDRGWWK
GDLDTNVTMDAEDLLLRQFLGIRDRATTDAAALFIRGEQRADGTWATFHGGPGELSTTIE
AYVALRLAGDAPDDPHMAKASAWVRERGGIAASRVFTRIWLALFGWWKWDDLPELPPELI
YFPKWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDARDPNPAKPLAPVA
SWDGAFQRLDKLMHGYQKVALGPLRRAAMNAAARWIIERQENDGCWGGIQPPAVYSVIAL
HLLGYDLDHPVLKAGLKSLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHP
ALVRAADWMIDEQIDRPGDWSVRKPQLEPGGWAFEFDNDNYPDIDDTAEVVLALRRVRHP
DPQRLERAIERGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSSDVTGH
VVEMLAVEGMAHDPRTRRGIEWLLAEQEPNGAWFGRWGVNYIYGTGSVVPALVAAGLPAA
HPAIRRAVTWLESVQNEDGGWGEDLRSYRYEDWKGRGASTASQTGWALLALLSAGERESK
AVERGVAFLADTQTEDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFTD
RIAAPAEGS
>A0A7T7VDA1|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium diazoefficiens|TrEMBL
MDSVNATSREAQESRILESGILESKVLESSIASATQGVLGLQQPDGHWVFELEADCTIPA
EYILLRHYLAEPVDAVLEAKIGNYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGD
AVDAPHMVRAREAIHARGGAIHSNVFTRFLLATFGVVTWRAVPVLPIEIVLLPFWSPFHL
NKISYWARTTMVPLMVIAALKPRAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFVLF
RALDGILRVVEPMFPKSLRQRAIDAALAFIEERLNGEDGMGAIYPPMANIVMMYDALGKD
ETYPPRAITRRGLDKLLVVKGDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLD
WLIPKQELEVKGDWAVKRPDVRPGGWAFQYNNAYYPDLDDTAVVVMSMDRMRREHGATGY
DTAIDRGREWIEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISML
AQLGQTATTSKHVVDGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDHNDPM
IRKAAAWLASIQNKDGGWGEDAKSYRLDYKGWEAAPSTASQTAWALLGLMAAGEVDHPAV
ARGVEYLIATQNEKGLWDESRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRSTNSRV
VGVGM
>A0A150KG99|squalene-hopene cyclase|EC 5.4.99.17|Weizmannia coagulans|TrEMBL
MRERPHKKTIMFPRFVHMYRKKERNGAMTKWDQKIDWLINRLKQDQSSDGSWAYPFDTGT
TTDAYMIILLRTLAVQEDQLIRGLAQRILSKQSDNGAWKLFADEENGGNLSATVEAYYAL
LASGFVKKDDPRLVSAKKFILEHGGIQNTSMFTKIMLAITGKYKWPAFSPFPVEMILLPA
ACPINLYQFSIFGRANLIPIMILASRKFSMKMKNSPDLSDLFSARHPGHSWPENRDLLDW
IGEELKKISEFPERLHASALDRAKKYMLARIEPDGTFYSYFSATFLMIFALLSLGHFKNG
PIIQNAVKGLLSMATVIDGLPHMQYTTANVWNTALISYAMQNAGVPKEDETVAAANRYLL
SRQHNRSGDWKIHNPHGAPGGWGFSDINTINPDVDDTTAALRALIREAAGGTQTREAWKR
GVNWTVSMQNRDGGWAAFEKNVHGKWLKLIPVEKAEYLLGDPSSADLTGRTLEFLGNYTN
LENRHPAMEEGADWLIRHQRKDGSWYGRWGICYLYGTWAASTGLAASGIPASRPALKRAA
GWIQSVQNHDGGWGESCRSDIHQTYIPLGHSTLTHTAWALDTLIAVSEKPTVEMEHGITW
LLSNLEKQDWTTAYPVGQGMAGTFYIHYHSYRYIFPLLALGNYRRKYS
>A0A840QKB0|squalene-hopene cyclase|EC 5.4.99.17|Saccharopolyspora phatthalungensis|TrEMBL
MTDQLQQPVGAIAVAEARTALDAARDYLLSLQHPDGWWKGELETNVTMDVEDLLLRQFLG
IRTAAETEQAARWIRSQQRRDGTWANFYGGPGDLSTTVEAYTALKLAGDDIDAEHMVVAR
DWILAQGGLEATRVFTRIWLALFGEWSWDELPAMPPELVLAPKWFPLNVSDWGCWARQTV
VPLTVVCTLRPRRDLGISVRELRTGRSGDPIRPQWSWEFAFHSLDRVLRRYQQRPLKTIR
RHAMLRAAEWIVARQEADGSWGGIQPPWVYSLLALNLLGYPLDHPVLRHGLAGLEGFLVR
EQTPAGPVRRLEACQSPVWDTVLAMQALSDAGAPADHPSLRRATNYLLAEEIQVKGDWSV
RRPHLPAGGGWAFEFDNDGYPDIDDTAEVLLALNRVDHSDPAAVRSAIERGIRWLRGMQS
KDGGWGAFDADNTRSLVRKLPFCDFGEVIDPPSADVTAHVVEALAALGHDDRVVRRGVQW
LLDNQEKDGSWFGRWGANHVYGTGAVVPALVRAGFKPGHRALRRAVKWLESHQNADGGWG
EDLRSYDDPAWIGRGDSTASQTGWALLALLAVDRHGTEAVRRGVQYLARTQRADGGWDEP
QFTGTGFPGDFYINYHLYRVIFPLTALGRYHRAAG
>A0A6M0A1V5|squalene-hopene cyclase|EC 5.4.99.17|Okeania sp. SIO3B5|TrEMBL
MIEKSKVKQSILASQNYLLNLQKPEGYWWGELESNVTITAEIVLLHKIWETDNKRPLEKA
KNYLISQQREHGGWELFYGDGGDLSTSIEAYMALRLLGVAKTDSIMLKAQEFIIKKGGIS
CSRIFTKLHLALIGCYNWQGIPSIPPSIMLLPEDFPFTIYEMSSWARSSTVPLLIVFDKK
PIFSVNPTINLDELYAEGINNATFELPRQYDMTDLFLGLDKAFKLAENFNLMPLREEGLK
AAEKWILERQEVTGDWGGIIPAMLNSMLALRCLEYDVADPIVVRGLEAIDRFGIETGDGY
WVQPCVSPVWDTAWVIRSLVDSGILPSHPAVVKAGEWLLEQQILDYGDWAVKNKLGKPGG
WAFEFINRFYPDIDDTAVVVMALDNVELPDEELKRVAIARAMEWVASMQCEPGGWAAFDV
DNDQDWLNGIPYGDLKAMIDPNTADVTARVLEMVGCCGLSMDSWRVKRAIAYLEREQEEE
GCWFGRWGVNYIYGTSGVISALAVVAGESHRGFIERGASWLVGCQNSDGGWGESCRSYND
PSLKGKGKSTASQTAWALIGLLAAGEATGNFARDVIDRGIDFLVSTQNDDGSWLESEFTG
TGFPCHFYIKYHFYPQYFPLMVLGRYKNLLGG
>A0A6G2VC92|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID2563|TrEMBL
MTATTDGSTGAVDPRAASARRTTTESTIAADGVLAAARRAAERSVEHLLGRQDEQGWWKG
DLATNVTMDAEDLLLRQFLGIQDPATVRAAAGFIRGEQLGDGTWATFHGGPADLSTTIEA
YVALRLAGDRPEDPHMVRAAGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMF
FPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPANPNPPKRPAPARS
WDGLFQRLDKALHVYHRFAPRRLRRVAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVMRAGLESLDRFAVWREDGTRMIEACQSPVWDTCLATIALADAGVAPDHPA
LVRAADWMLAEEIVRPGDWAVRRPGLEPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPD
QARVDAAIERGVRWNVGMRSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHV
VEMLAVEGRAEHPVTRRGIEWLLSEQDPAGGWFGRWGVNYVYGTGSVVPALTAAGLPPSH
PAIRRAVEWLESVQNDDGGWGEDLRSYTEEKWIGQGASTASQTAWALLALLAAGRRDTVA
VTRGIAWLTETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFAGR
TPTREGA
>A0A6I2MD54|squalene-hopene cyclase|EC 5.4.99.17|Metabacillus idriensis|TrEMBL
MNDLNKQIKRMTDELRQLQQNDGSWRFCFEGGPMTDAFMIILLRSLQDDDDVLIKKLTNR
LLNLQSNEGTWKLYEDEKEGNLTATVQAYTALLSTGLYKKSDPLLNRAESFIVSQGGLAN
VHFMTKWFLAVNGLYPWPKYFRFPLAYLLLPAKSPISMYQLSSYARIHFMPMILAMNKRF
IHSTNHSINLSHLHVSKPRSIDWLSFSDSHRTKHIFTETLRSFAGFPAYVHRAGENAAEK
YMLKRIEADGTLFSYASATFFMIYALLSLGYKENSAQIKQAVAGLKSIIYQDDNLITVEN
STSTVWDTALLCYSLQKAGIPYHDSMIINASSFLLSRQHVKKADWRIHNPSASPGGWGFS
NINTNHPDNDDTAAVLRALTQLSALDPVYFEAWNKGSSWLLSMQNRDGGFGAFEKNVNNP
IFASIPLENAKDAAIDPSTADLTGRVLEYFGNFAGLTKEHPSIQAAVAWLLHQQEQNGSW
YGRWGVCYIYGTWAAITGLKAAGLSNSHPAIVKAVKWLVRIQKEDGGFGESCRSSEVKTY
MPLEFSTPSQTAWALDALLCVMDKKDTAIQRGVKRLMKPFDEKSSAYPTGIGLPKQFYIH
YHSYNKIFPLLALSHYRNLH
>A0A5C4L7M6|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium terricola|TrEMBL
MGKVETLHRKSTQDVTLDEVERRVSAASRALTQLAQADGHWCFELEADATIPSEYILYHH
FRASIPPRELEEKIAVYLRRTQSPLHHGWALVHEGPLDMSATVKAYFALKMIGDSPDAPH
MRRARDAILQRGGAAHANVFTRTLLALYGEVPWSAVPVMPVEVMLLPRWFPFHLDKVSYW
ARTVMVPLFILQMKKPRAKNPRGIGVRELFTQDPARIRRWPSGAQEASPWRPVFAVIDDI
LRVVEPLFPAGPRAKAVDKAVAFVSERLNGEDGLGAIFPAIANSVLMYEALGYPEDHPLV
VTARSAVEKLVTVKEHEAYVQPCLSPVWDTALAAHALMEAGGPENERQARAALEWLKPLQ
VLDIKGDWAARKPDVRPGGWAFQYNNPHYPDLDDTAVVAMAMDRAQTRLGPGEGGSDYTQ
SIARAREWIEGLQSRDGGFAAFDADNTYHYLNYIPFSDHGALLDPPTADVTARCISMLAQ
LGETKATSPALARAVDYLLADQEEDGSWYGRWGMNYIYGTWSALCALNAAGQDPSSAPIR
KAVEWLVAIQNPDGGWGEDAASYKLEYRGYERAGSTASQTAWALIALMAAGEADHPAVAR
GINYLARTQGADGLWGEEFYTGTGFPRVFYLRYHGYAKFFPLWALARYRNLQRGNSRRVA
VGM
>A0A0S4L239|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Nitrospira nitrosa|TrEMBL
MNLIKALFNRLSDSLLSGTPGRLDHATEFNPVAPLRLVSEKPVVLPALDTAAGRRPIGHA
VGQPDSVDEAIKRSQSWFFARQHAEGYWVAELEADTTLTSEYLMLRRFLDRVDPKREEMA
VQYLKSMQLPDGGWPIYYGGPSEISASVKAYFALKLSGVSADEPFMIRAKEGILAMGGVL
QANVFTKITLALFEQYDWEGVPHMPVEIMLLPKKFYFSIYAISYWSRAVLIPLLIVFAHR
PVCRIPRDQGIDELYSVPREEVRYWKYPPFNKDQAWFTPHNFFVALDAMLKLYDRMPMRA
LREKALHKAAAWMVDHIKGSGGLGAIYPAMANSIMALECLGYKADDPLVVKALREIEELE
VYDSAMMDGERVSTVHLQPCFSPIWDTALLTNALIEAGVSQDHPSLQKAGRYLMSRQAKT
VGDWIISSPSAEPGGWYFQFENELYPDVDDSAVVIMALSKLKIPEQEGELDESMRRGMQW
VLAMQGSDGGWGAYDKDNNRVVFNYIPFADHKALLDPSTADLAGRCLEMLGALGYDQTHP
SAGPALAFLKKEQEKDGSWYGRWGVNYIYGTWSVLAGLRAIGEDLSAPYIRRAVSWLESK
QNSDGGWGESCLSYRDDGDDHGKGESTPSQTAWALMGLMSAGAVDSFSVARGVQFLLRQQ
TKDGSWQEIAHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNVRSRGKTRADELRHHLKGA
DLPRAEH
>A0A832E340|squalene-hopene cyclase|EC 5.4.99.17|Crenotrichaceae bacterium|TrEMBL
MFDDSVTASLSTVQETHKTVFNDSDLSLNEAIQNAQQAILNHQDPEGYWVYELEADTTIP
SEYIMLMHYTGDIDELLQIKMARYIRSKQNDDGSYPLYIGSEGDISVTTKAYFALKLAGD
AIDAPHMRKAHDYIRSQGGVAKCNVFTRIALAIFELLPWRGVPYIPVEIMFLPQWFPFHL
TKVSYWSRTVMVPLFVLCTLKAKAKNPKNINLDELYVIPPDQEYNYFAKNDWLDRVFLAL
DRVGKSCDRFIPGFVRQKALKKAENWIIERLNGEDGIGGIMPAMTGAYQALLLLGHDHDS
EHVKTAKQALEKLLVVRTHDAYCQPCLSPVWDTGLAILALQQSDFYANKTAIDQGIHWLL
RKQLSDEPGDWRDLRPDVAGGGWAFQFENPHYPDVDDTAVVGYALQLMNNPALDEPILRA
ARWIAGMQSHNGGWGAFDADNTHYALNHIPFADHGALLDPPTVDVSARCIMFLARLVDQY
PEFQPVIDRGVEYLRDEQEVDGCWFGRWGTNYIYGTWSVLVALGELGMRKDDPMLQAGVD
WVLQKQKEDGGWGEDNHSFHDPADRGRYYMSTAFQTAWSLLGLMAVGYADTPQVKAGVDF
LLRKQQEDG
>A0A7C7BSZ7|squalene-hopene cyclase|EC 5.4.99.17|Rhodospirillales bacterium|TrEMBL
AAQNPRGVNIDELFHKPPYRENYKLTNPTGGWVGSLMLVLDRSFRPFEHLIPNLITQKAI
TLGLKFMENRLNDEDGLGGIFPAIANSLMVFDCLGYKNDDPRVVSARKAIDNLLVIKDDE
VYCQPCLSPVWDTGLSAHAVLEASIKKTDDLLDRSSEWLKNLQILDQIGDWAHRRKNLKP
GGWAFQYRNDFYPDVDDTAVVAMALHRQDPKKNAESIKRAEEWIIGMQSSNGGWAAFDVE
NEYYLLENMPFADHGALLDPPTSDVTARCVSLLGQIGYGMDHKAISKGFSFLKREQEKDG
SWYGRWGTNYIYGTWSVLSALNMVGEDMSAPYIRRAVNWLELRQREDGGWGEDCATYWEH
RKNTAKASMPSQTAWAVLGLMASGEVNSKAVARGVDYLINQNNKNTGWEDKYFNAVGFPR
VFYLKYHGYSLYFPLLALARYRRMKPSNIQSPKFGI
>A0A4U1I574|squalene-hopene cyclase|EC 5.4.99.17|Trinickia sp. 7GSK02|TrEMBL
MNDLTADNLADAAVTEATPFAEPQAGAAARAPANPALDAAVTRAVDALLAAQRPDGHWVY
ELEADATIPAEYILLVHYLGETPNLELEQKIARYLRRIQLADGGWPLFTDGKLDVSATVK
AYFALKMVGDPEDAEHMQRARRAILAHGGAEAANVFTRILLALFGVIPWHAVPMMPVEIM
LLPMWFPFHLSKVSYWARTVIVPLLVLNAKRPKAKNPRGVRIDEIFRGAPVSTGLLPRAG
HQSQGWFVFFRGVDAILRTVDGLFPRITRQKAIDAAVAFVDERLNGEDGLGAIFPAMANS
VMMYDVLGYPPDHPNRAIARKSVEKLLVIGEEEAYCQPCLSPVWDTSLAAHALLESEEPR
AEEAALRGLQWLRPLQILDVRGDWISRRPNVRPGGWAFQYANPHYPDVDDTAVVALAMDR
AATLTKSNVDREAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTA
DVSGRCLSMLAQLGEMPANSEPARRAYDYILKEQEADGSWYGRWGMNYIYGTWTALCALN
AAGISHEDPRIKRATQWLISIQNDDGGWGEDGTSYKLDYRGYERAASTSSQTAWALIGLM
AVGVVDHPAIERGVAYLTSTQQAHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARY
RNLKRDGLKRVTVGL
>A0A552LK39|squalene-hopene cyclase|EC 5.4.99.17|Microcystis flos-aquae Mf_WU_F_19750830_S460|TrEMBL
MQIQEKITEIAAKTAKAIELSQNYLLSTQYSDGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPANDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNNWSDVFLWLDGLFKWAEKTNLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVDDPIVARGLKAVDNFAIQ
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKSVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGSCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A6H1LGB2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. RLB1-33|TrEMBL
MTATTDGSTGALPPRAAAASEIHPETTPVAAGAVETRDVATHAIQRATDFLLSRQDAEGW
WKGDLETNVTMDAEDLLLRQFLGIRDETTTRAAGLFIRGEQREDGTWATFYGGPGELSTT
IEAYVALRLAGDGPDEPHMARAAAWIRERGGIASARVFTRIWLALFGWWKWDDLPELPPE
LIYFPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDARDPNPVKPLAP
VASWDGVFQRLDKALHQYRKVVPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVI
ALHLLGYDLQHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPAD
HPQLVKAADWMLGEEIVRPGDWAVKRPHLPPGGWAFEFHNDNYPDIDDTAEVALALRRVR
HHDPERVEHAIGRGVRWNLGMQSKDGGWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVT
AHVVEMLAVEGLSHDPRTRRGIEWLLAHQEPDGSWFGRWGVNYVYGTGSVLPALVAAGLP
ASHPAIRRAVAWLETVQNDDGGWGEDLRSYHEVAEWSGRGASTASQTGWALLALLAAGER
DSKAVERGIAWLAETQLADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEP
SFVHGESFAEVKGG
>A0A375GLU6|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus oxalaticus|TrEMBL
MSMNETAFATTAPPIRIAADPAFAPAFGQQSAAQELDHGIGVAVDALLHQQRPDGHWVYE
LEADATIPAEYVLMVHYLGEAPDLALEARIARYLRRIQNADGGWPLFHDGRADVSASVKA
YFALKMAGDDPQAPHMARARQAIHAMGGAEATNVFTRTLLALYGVMPWTAVPMMPVEIML
LPRWFPFHLSKVSYWARTVIVPLLVLNSLRPRARNPRGVGIGELFSNPRRSVGLAPRAPH
QHAGWYNLFRGLDALLRVAEPAFPGLLRRRAIAAAQRFVRERLNGEDGLGAIFPAMANSV
MMFDVLGVPADDPARAVARRSVERLLVEHGDEAYCQPCLSPVWDTALAAHALLETGEARA
AAAVGRALDWLKPLQVLDVRGDWSVRRPRVRPGGWAFQYANAHYPDVDDTAVVAAAMDRY
MREHAAPGRYDEAAARAAEWIVGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDPPTA
DVSARCLSMLCQTGATPASSEPAARALRYLLAEQMPDGSWFGRWGTNYIYGTWSALCALN
AAGLGPDAPAVRRAADWLAGIQNEDGGWGEDGGSYRLDYRGHEPAPSVASQTAWALLALM
AAGAVQHPAVARGIGYLLRTQRPPQEGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWAL
ARYRNLQRGGDDGGGGEGRVTWGL
>B1Z3J0|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia ambifaria (strain MC40-6)|TrEMBL
MNKPAPSPWSALDTAIARGRDALMRLQQPDGSWCFELESDATITAEYILMMHFMDKIDDV
RQEKMARYLRAIQRLDTHGGWDLYVDGDPDVSCSVKAYFALKAAGDSEHAPHMVRARDAI
LALGGAARSNVFTRILLATFGQVPWRATPFMPIEFVLFPKWVPISMYKVAYWARTTMVPL
LVLCSLKARARNPRNIAIPELFVTPPDEERHYFPPARGMRRAFLALDRVVRHVEPLLPKR
LRQRAIRHAQAWCAERMNGEDGLGGIFPPIVYSYQMMDVLGYPDDHPRRRDCENALEKLL
VTRTDGSMYCQPCLSPVWDTAWSTMALEQARAVAVPEAGARASALDELDARIARAYDWLA
ERQVNDLRGDWIENAPADTQPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRTHRNADGSH
PYAARVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSGRVLL
CFGVTKRAADRASLARAIDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALAGEDPSQP
YIARALAWLRARQHADGGWGETNDSYIDPTLAGTNAGESTSNCTAWALLAQMAFGDCESE
SVRRGIAYLQSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLASGVS
SAGVHAVPASTGADAALA
>A0A6I5D5Y1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4982|TrEMBL
MTATTDGSTGATIPPRAAAASDTDSTTPLAAGVHQAAERAVLRATEFLLAGQDPEGWWKG
DLETNVTMDAEDLLLRQFLGIRDEATTSAAALFIRGEQRADGAWATFYGGPGELSATVEA
YVALRLAGDAPDAPHMARASAWVRERGGIASARVFTRIWLALFGWWKWEDLPELPPELIW
FPTWLPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPANPNPPKPLSPLAS
WDGAFERLDRVVHRLRKAVPRRVRRAAMNAAARWIVERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLAVIALADAGLPADHPQ
LVKAADWMLGEEIRRPGDWSVKRPQLPPGGWAFEFHNDNYPDIDDTAEVALALRRVRHPD
PGKVDGAIGRAVRWNFGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMMAAEGLAHDPRTRRGIAWLLAEQEADGSWFGRWGVNYVYGTGSVVPALTAAGMPASH
PAIRRAVHWLQRAQNDDGGWGEDLRSYKHAKEWSGRGASTASQTGWALMALLAAGERDSE
AVERGVRWLTGTQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFDK
APLAAHRGRRAVLGGS
>A0A4R5KKH0|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus piri|TrEMBL
MSSEIHEEIRRLTTALIQQQQQDGSWRFCFENGTTIDAYVIILLRTLNIQGNENLVRQLH
DRILIEQQPEGSWKLFPDEEEGNLSASVEAYYALLYSGYSRTTDEPMRRAKRFIQTKGGL
GKVTSILTKAILAATGHSKWPASISSIPLELLLLPASFPISFFDFSGYSRVHLAPMLIMA
DRHFSIKTSHAPDLNDLHVDRNDTDEQLPREFHETLDRIQTGLNRLIGTPRYIHEAALTK
AEQFILQRIESDGTLYSYASSTILMIFALLALGYDGQHPLIAHAVQGITAMRCSFDGKTT
MQNSPSTVWDTALLAYAMQEAGIADDHAAIRSAAAYLLSRQQRKPADWSLHNPNITPGGW
GFSETNTINPDVDDTTAALRAIRSLSRTDPSYRDSWNRGLNWVLSMQNDDGGWPAFEKNT
NKQMLTWLAIDGAKSAAIDPSEADLTGRALEYLGNFGGFDIRHKFIKNGTDWLINHQEKD
GSWYGRWGICYIYGTWAALTGLKAAGISSDHEAMQKGAKWLLSIQNSDGGWGESCRSDRL
LYFVPLEESTPSQTAWALDALIAVHSRPTAAMNNGIRTLIGLLRENNRAASYPTGAGLPG
NFYIHYHSYRYIWPLLALSHYIRKYEG
>A0A0J1FFD9|squalene-hopene cyclase|EC 5.4.99.17|Peptococcaceae bacterium CEB3|TrEMBL
MVEKREVEQAAAQARQFVFTGVRQVLSGKLDEAHGVSASPGATALAVLALLTAGRDFGGA
ERRGITWLRQHRQGQGWGRYPGDSPDPEISRLVQAVTQSGQGGWISRVVLLSRARQFSEM
ILSLGQKVVPGLEGPTPEEIVLPGILRETVLTKLPAYGRPVVVAAALLASNERQGIRPAT
DYLVNFQMGDGSWSEDVVATSLAILALVRWHIAGDKVGKAGEWLVRKQYGDGSWPAFDHL
QNWSVGWALNIMEGREREETELLSQTERWLKRGQYADGSYGSTSPYTQPDLDDTAVALLG
LSASPESRKGVELLKRLQNKDGSWGTFPSFVGKPPNLECGFPVYIRSTDVTLHILEALWR
HRSRGEYQTMVKGLEWLLTKQKTSGVLDSVWFEGPIYGTAQLAEFLEKWRFNWQNWTGAR
RALLARRKALDFLWAAQNPDGSWGSSVAETALGLSAVGYPGKRGGKEALTKGVERLMADQ
LPAGSFKPSYRGIYAKGWNYEEPLATALTVIRAWEKYLHLTF
>A0A429PRI6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. WAC08241|TrEMBL
LARPRSADAGKTFPNGGPTSPPARPGRPGGGGGRRAWRGSPRPPRPLAPPTGWDGVFQRL
DRALHLYHRVAPRPLRRVAMNLAARWIVERQENDGCWGGIQPPAVYSVIALHLLGYDLGH
PVMRAGLESLDRFAVRREDGSRMVEACQSPVWDTCLATVALADAGLPPDHPALVKAVDWM
LDEEITRTGDWAVRRPGLPPGGWAFEFHNDNYPDTDDTAEVLLALRRVRHPDPARVGAAA
ARGARWTLGMQSRNGAWGAFDADNTSPFPNKLPFCDFGEVVDPPSADVTAHVVEMLAHEG
LAQDPRTQRGIEWLLAEQEPHGGWFGRWGVNHVYGTGSVLPALAAAGIPATHPAVRRAVA
WLGSVQNEDGGWGEDLRSYQDEQWVGRGASTASQTAWALLALLAAGERESEPVRRGIAWL
VETQLPDGSWDEPYFTGTGFPWDFSINYHLYRLVFPLTALGRYVYGEPSPRKEG
>A0A7C3FMZ7|squalene-hopene cyclase|EC 5.4.99.17|Caldilineae bacterium|TrEMBL
MGLEVTVEIDLDLLQQAIRRAQEYLLGLQKPEGYWIGELEADASVTAGYIPVMHFMGRRI
SEERKQRIIQFLKSRQNTDGSWPAYHGGPGDLSVSVQVYFALKLAGVSAEEPFMKKAREF
IRARGGVARTNVITRVWLACFGQFPWSDIPIMPPELIFLPKWFYFNIYEFSSWARATIMA
LALLSHLRPLCPVPEGRGVEELYLEGEWPRPPGHGKGMISWENFYLVVDRILKAYQKSPI
KPGRGTALRKVEEWVVAHQDADGSWGGILLPWVYSLYALKELGYPDDHPVIQKGLEGLED
FILEDEERGFRLQPAVSPIWDTAWAIIALRDSGLPPDHPALLQAARWLLKKEIRVKGDWA
VKNPRIEPGGWAFEFENNYYPDIDDSAVVPLGLLRVKLPESEEPQKLQAIRRAANWVAGM
QSSDGGWAAFDKDNNKRALAHIPFADFVTPLDPTSPDVTSHAIEFLSAIGGFKERVRKGV
EYLKNAQEADGAWFGRWGVNYIYGTGLVLPALKAAGEDVRSQYIQEAVRWLKSHQNEDGG
WGESCASYDDPHLRGQGPSTASQTAWALLGLIAAGEAKSPEVRKGVRFLLETQREDGSWE
EEAFTGTGFPRAFYLRYHLYPVYFPLLALARYQREVIDNENNENSAGRDES
>A0A7H8IKA7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. NA02950|TrEMBL
MTATTVQPSESPESETLGAARKATARAVDHLLSRQDEQGWWKGDLETNVTMDAEDLMLRQ
FLGIQDARLLDAAARHLRAQQGEDGTWATFHGGPPELSATIEAYVALRLAGDEPDAPHMA
AAAAWVRAEGGIARSRVFTRIWLALFGWWRWEDLPELPPEIIYFPKWLPLNIYDFGCWAR
QTIVPLTIVSAHRPVRPAPFPLDELHTDPRRPRPPRRPAPVASWDGAFQRLDRVLHAYRK
VAVRPLRRAALRSCARWIVERQENDGCWGGIQPPAVYSLIALHLLGYDLDHPVMRAGLAS
LDRFAVWREDGSRMIEACQSPVWDTCLATIALADAGLDPDHPALVKAADWMLGEQIDRPG
DWSVRRPGLPSGGWAFEFHNDHYPDIDDTAEVILALRRVDHPEPERIEAAVRRGMRWTLG
MQSKNGAWGAFDADNTSPLPNRLPFCDFGEVIDPPSADVTAHVVEMLAHEGRSYDARTRR
GISWLLAGQEPSGAWFGRWGTNYVYGTGSVVPALIAAGVPASHQAVRRAVRWLESVQNED
GGWGEDQRSYPDPEWIGRGASTASQTAWALLALLAAGERESKAVERGVEWLAAAQGEDGS
WDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRFVHDEATGARPRRS
>A0A8F6LBV5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. WY228|TrEMBL
MTATTDGSTGAANLSGAPADDPTDTTTAADDVTAAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDAETTRAAALFIRGEQLGDGTWNTFYGGPGDLSATIEAY
VALRLAGDRPDEPHMARASGWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPDHPNPARKLAPPASW
DGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVMKAGLASLDRFAVRREDGARMVEACQSPVWDTCLATIALADAGLRPDHPAL
VKAADWMLAEEITRPGDWAVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARMQAAIDRGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLANHPRTREGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALIAAGLPAGHP
AIRRAVGWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDTASV
ARGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRA
DAVEGA
>A0A7W6RAW1|squalene-hopene cyclase|EC 5.4.99.17|Roseospira visakhapatnamensis|TrEMBL
MTHALPKANNVIEFEPRASLASPGRPVRGFPASSVAAHAVAPDPVFADAPPQGHETEIPP
STPDLNGADLDDTIADAASWLQGRQDGDGHWVFELEADATIPAEYILLNHFLDQVDDPLE
RRIAVYLRRGQGPHGGWPLFHDGDFNISASVKAYYALKLVGDHPDEPHMVRAREAILAHG
GAAASNVFTRYTLAMFGQVPWRACPVARVEAMLLPRWFPFHLDKVSYWARTVMVPLFVLY
SRRARAENPRGVDIRELFITPPEKERRYHTNPTGHWLGRVFLGVDAVARLLEPLFPTVAE
RKATEKAMAFIGARLNGVDGLGAIFPAMANALMVFHILGYGRDHPQVRVARQAIDGLVIE
KGDHAYVQPCLSPVWDTGLASLAMAEVDAQAHGLDTRGAAMRESAVANACGWLRDRQVLD
TVGDYAAWRPDVRPGGWAFQYNNDHYPDVDDTAVIGMLLDRARLPENKEAIDRAAEWILG
LQSENGGWGAFDADNEYYVLNNIPFADHGALLDPPTVDVSARCLGFLAQLGYDRDHPAMA
RGLVYLREQQEPDGSWFGRWGTNYIYGTWSALAAFNAVGEDLQAPHIRAAVAWLHRRQQA
DGGWGEGCESYWTEKRDFVKASTPTQTAWAVLALMAAGEVDSPEVKRGIAYLMKAPRDGG
MWDEKLYNAVGFPRVFYLKYHGYPAFFPLWALARYRNLTRGNSQRVSWGL
>A0A7W4IEB1|squalene-hopene cyclase|EC 5.4.99.17|Gluconacetobacter sacchari|TrEMBL
MVNATDTLERLSAGVADRAVSMSDIDRAVDSAHAALGRRQNDDGHWVFELEADATIPAEY
VLLEHYLDRIDPALEARIGVYLRRIQGDHGGWPLYHGGRFDLSASVKAYFALKAIGDDID
APHMARARAAILDHGGAERSNVFTRFQLALFGEVPWHATPAMPVELMLLPRRAFFSVWNM
SYWSRTVIAPLLVLAALRPRAVNPRDVHVPELFVTPPDQVRDWIRGPYRSPLGRVFKYVD
KVIRPGERLIPEATRRRAIKAAVDFIEPRLNGVDGLGAIYPAMANSVMMFRALGVPDSDP
RAATAWESVRRLLIEHGDEAYCQPCVSPIWDTGLAGHAMIEAASGPEGIRPEETEKALAA
AAQWLRDRQILDVKGDWAINCPDVAPGGWAFQYNNDHYPDVDDTAVVGMLLHREGDPAHR
EAIERARQWIIGMQSSNGGWGAFDIDNNLDFLNHIPFADHGALLDPPTADVTARCVSFLA
QLGNPDDQPVIERAIAYLRRDQEAEGCWFGRWGTNYIYGTWSVLCALNAAGVSHDDPAVV
RAVDWLRSVQREDGGWGEDCASYEGATPGVYTESLPSQTAWATLGLMAAGLRDDPAVARG
MAYLARTQKEDGEWDEDPYNAVGFPKVFYLRYHGYRQFFPLMALARYRNLESSNTRRVAF
GF
>A0A7K2TZN1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8358|TrEMBL
MTATTDGSTGAANLRAVPFGDPIEPTIDTDDVLAAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPATVQAAARFIRGEQLGDGTWNTFHEGPADLSATIEAY
VALRLAGDRPDDPHMIRAAGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMFF
PTWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFTLDELHTDPEQPNPPRPLAPVASW
DGVFQRLDKALHVYHKVASRRLRRIAMNAAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVMRAGLASLDRFTVWREDGSRMVEACQSPVWDTCLATIALADAGVPSDHPAL
VRAADWMLGEEIVRPGDWSVRRPQLAPGGWAFEFHNDNYPDIDDTAEVALALRRVRHPDQ
PRVDAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGRADDPRTRRGIRWLLDEQEACGAWFGRWGVNYIYGTGSVVPALIAAGLPTGHD
AVRRAVAWLESVQNDDGGWGEDLRSYREEKWIGHGSSTASQTAWALLALLAAGEREGRAV
QRGVTWLAETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFAKGA
GTGPGAASGKGA
>A0A7G8BW26|squalene-hopene cyclase|EC 5.4.99.17|Edaphobacter sp. 4G125|TrEMBL
MKEVPGIVFDGGQASYNLQALAPFVQAAVRNTSVHEARETAARAATTLQAQQNPEGYWVG
DLTADTTLLSDYILLQMWLYPPAANGSWDPPTMPKIRKAAKSLLETQRPDGGWNIYEPGP
SEINATVRAYTMLKMTGLSPEDPRMQKARTLILKMGGIQACNSYTRINYSFFDLFPKKYC
PTIPPEIMIIPGSVLYEMSSWTRTIIVPLSIVQALGGTRPTPGGLRIEELFHPNKRIALH
RKDRIANLFIRADKLFKRWERQSVKKIRDRAIREAEHWMLDRLHYSEGLGAIYPSIMYSI
MAMDVLGYERDHPDLMEAIGHFDGLMLESEEGMVFQPAKSPVWDTAIGAFALGEAGQGNP
EQMTAAADWLLSKEIRRRGDWATKRPNLTPSGWVFEFANEFYPDIDDTAMVLLTLLHAKA
SDPERQKRAERRAVDWLLGMQSSDGGWAAFDVDNNWQILNKVPFADHNAMLDPTCPDITG
RVIESLCKRGFDCTHPAIIRGVHYLLSHQEENGSWYGRWGVNYIYGTFLALRGLVASGAP
GAVEAIARGAHWLREIQNPDGGWGESCLGYDTERFERAVSTPSQTAWALLGLMAAGGVRS
NSVQDGVRWLCENQRPDGTWDETITTGTGFPGVFYISYHLYRNYFPLLALGVYGKRSKS
>A0A8I1UNM3|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MNEMVIDRAGPRVDSTIEKAKTALLALQREDGHWVFELEADATIPSEYILLVHYLGEKPD
LTLEAKIGNYLRRVQGAHGGWPLFHNGAFDISATVKAYFALKMIGDDINAPHMVRAREAI
LAHGGAAHANVFTRILLALYGQLSWKNVPTIPVELILVPRWFPIHLWKMSYWARTVLVPL
LVLAAKKPLARNPRKIGVDELFAPGRRTPPGRAPHQSRAWYAFFHTLDKVLKVVEPYWPS
RLHQRAIDACVAFVTERLNGEDGLGAIYPAMVNSVMMFDLLGYPANHPDRAIARRSVEKL
LVVKEDEAYCQPCVSPVWDTALACHALMETREGDTSEKVVRGLEWLKTRQVLDVKGDWVD
EKPNVRPGGWAFQYNNAHYPDLDDTAVVVMALDRARDSIAPQADYGEAIARGREWVEGLQ
SRNGGWGAFDADNSYHYLNNIPFADHGALLDPPTEDVTGRCIGMLAQLGEAPDSPRMKEA
IAYLERVQMKDGSWFGRWGVNYIYGTWSVLAGLNAAKVDPQTPMIRRAADWLVSIQNGDG
GWGEDCASYKLDYAGYEQSVSTASQTAWALLALMAAGDVNHPAVARGIRYLQDTQDEHGL
WPQEEYTGGGFPRVFYLRYHGYPKFFPLWAVARYRNLTQSNSRAVAYGL
>B7JHB3|squalene-hopene cyclase|EC 5.4.99.17|Bacillus cereus (strain AH820)|TrEMBL
MLLYEKAHEEIVRRATALQTMQWQDGTWRFCFEGAPLTDCHMIFLLKLLGRDKEIEPFVE
RVASLQTNEGTWKLHEDEVGGNLSATIQSYAALLASKKYTKEDANMKRAENFIQERGGVA
RAHFMTKFLLAIHGEYEYPSLFHLPTPIMFLQNDSPFSIFELSSSARIHLIPMMLCLNKR
FRVGKKLLPNLNHIAGGGGEWFREDRSPVFQTLLSDVKQIISYPLSLHHKGYEEIERFMK
ERIDENGTLYSYATASFYMIYALLALGHSLQSSMIQKAIAGITSYIWKMERGNHLQNSPS
TVWDTALLSYALQEAQVSKDNKMIQNATAYLLKKQHTKKADWSVHAPALTPGGWGFSDVN
TTIPDIDDTTAVLRALARSRGNKNIDNAWKKGVNWIKGLQNNDGGWGAFEKGVTSKLLAK
LPIENASDMITDPSTPDITGRVLEFFGTYAQNELPEKQIQRAINWLMNVQEENGSWYGKW
GICYLYGTWAVMTGLRSLGIPSSNPSLTRASSWLEHIQHEDGGWGESCHSSVEKRFVTLP
FSTPSQTAWALDALISYYDTETPAIRKGVSYLLSNPYVNERYPTGTGLPGAFYIRYHSYA
HIYPLLTLAHYIKKYRK
>A0A537UGN9|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MHSVNKSVGIENGALEASIAAATRALLGYRKPDGHWVFELEADSTIPAEYVLLRHYLGEP
VDAVLEAKIANYLRRVQGAHGGWPLVHDGDFDMSASVKAYFALKMIGDSVDAPHMVRARE
AIRSRGGAIHSNVFTRFLLAMFGVLKWRSTPVLPIEIMLLPMWSPFHINKISYWARTTIV
PLMVLAALKPQAKNVSSVGVDELFLQDPHSIGMTAKAPHQNWGWFLLFRGLDAILRVIEP
LFPKKLRARAIDSAVAFIEERLNGEDGLGAIYPPMANTVMMYEVLGKPADYPPRAITRRG
LDRLLVIGEHEAYCQPCVSPVWDTSLACHALIEAGGEEAFAPAKQGLDWLLPKQVLDIKG
DWVVKRPDVRPGGWAFQYNNAYYPDLDDTAVVVMAMDRTRQATRSREYDTAIARGREWIE
GMQSRDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCVSMLAQLGETAQSNKA
LAAGIAYLRRTQLAEGSWYGRWGMNYIYGTWSALCALNVAGVDHQDPGIRKAVAWLVSIQ
NEDGGWGENATSYRLDYKGFEDAPSTASQTAWALLGLMAAGEVGHPAVARGVEYLIATQT
EKGLWDEQRFTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNNRVVGVGM
>A0A7L4Z6L1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. HF10|TrEMBL
MTATTDGSTGATLPSRAAAASDTTLTTPEAAGVPEAAARAARRATDFLLSRQDAEGWWKG
DLETNVTMDAEDLLLRQFLGIQDERTTQAAAKFIRGEQRADGTWATFWGGPGELSTTIEA
YVALRLAGDAPDAPHMARAAAWIRERGGIASARVFTRIWLALFGWWKWEDLPEMPPELIW
FPGWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPANPNPARPLAPANT
WDGAFQRLDKALRQLRKVVPRRLRRAAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVLREGLASLDRFAVWREDGARMIEACQSPVWDTCLAAIALVDAGLPVDHPQ
LVKAADWLLGEEIVRPGDWAVKRPQLPPGGWAFEFHNDNYPDIDDTAEVSLALRRIRHHD
PERTDRAIGRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAAEGLAHDPRTRRGIAWLLAEQEQNGAWFGRWGVNYIYGTGSVVPALTAAGMPGSH
PAIRRAVSWLESVQNDDGGWGEDLRSYQHVKEWAGRGASTPSQTAWALMALLAAGEKDSR
AVERGVQWLAATQREDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFER
QLLAKAPRPRPVEAKPTGSPLSEAKGS
>A0A3E0LGC2|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa TA09|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSDGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPTLEKAREFI
LAQGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNNWSDVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDPGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKAVDNFAIE
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKGVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVNMEENRVKKALDYLEI
EQETDGSWFGRWGVNYIYGTSGALSALAFLEPNKYHQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVRKVTGNYQREVIEQGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>E8WXM9|squalene-hopene cyclase|EC 5.4.99.17|Granulicella tundricola (strain ATCC BAA-1859 / DSM 23138 / MP5ACTX9)|TrEMBL
MSAATPINPEATKQPRFGRIDLGLEVIANGIKRSAEWLLGLQHPDGYWCGELEADSMLES
DYIFVHTLLGTGDPGRLSRALNEILRHQNDDGGWSLYPGGPSNVNYGVKAYLALKLMGYT
ADHPVMVKARECVLRLGGVVECNTFTKIYLCGLGQYDYDAVPAVPPEIVLFPDWFYFNIY
EISAWSRAILVPLSIIYAKKPFKKLTPEQGIDELFVGGRAGANLRLRWDKKHPLSWRNVF
LFLDRVAHLAERVHIRPLRSIALKKAERWMLDHFERSDGLGAIYPAMLNAIVALRCLGYS
ADDPQVIRAMDEFERLGIDCPEGTPDYPTPTFRMQPCFSPVWDTAQVLSTLGDCGLPRND
ERLVKAADWLLSKEIRYKGDWSHTVKNVDASCWCFFFNNDHQPDVDDTGEVLLALKAVDN
PRERYQHETAQRAIEWVFAMQCKNGGWASFDKDNTKKIFESIPFADHNAMIDPPSVDITG
RILEMLAGYGYTRRDPRIEKAVQFILREQEPDGCWFGRWGVNYLYGTFLVLRGLQSMEYD
PYEPAVQQAAEWIRMVQNSDGGWGETCGTYDNPSLKGTGPSTPSQTAWALLGLLAANDTR
SDSVAKGVRWLIDRQHEDGSWDELAAGRNGESHYTGTGFPTVFYLGYHLYKQYFPLLALT
TYKQAMERESAAA
>A0A4V5TIP3|squalene-hopene cyclase|EC 5.4.99.17|Brevibacillus antibioticus|TrEMBL
MRIDTTTNPSMLFPLSFSDVVFYREVNELREVLQEINRIQAFLLQRQQEDGTWRFCLESS
PMTDSHMIILLRTLGIHDERLMEKLTAHITSLQHDNGAWKLYPDEYEGHLSTTIDSYYAL
LLSGKYTKNEPRMALARSFILEKGGLTQANMLTKFSTALTGQYQWPSHFLVPVEIALFPP
SSPVSFYDFVGYARVHLAPMMIVADRNYVKKPDNAPDLSDLYADTPISRGLYPHRFLENF
LKEGQSFLATIHDSLQRLPFLPGQLHKLALRRLEQYILARIEPDGTLYNYSTSTFFMIFA
LLAQGFSPKDPLIQKAMQGLMNSVYEYENGAHLQLATSAVWDTALLASSLQKSGLSTTHP
AIQKANRYLLQKQQHTYGDWKIRNPTGKPGGWGFSDYNTMNPDIDDTTAALRSLRLLART
NITSAAAWKRGLEWLLSMQNDDGGWPAFERNTDADFIRHLPIEGADTVSTDPSSADLTGR
TLEFLGNDAGRALTDPHVEKGVRWLLKHQESDGSWYGRWGIAYLYGTWAAITGLMAVGFS
PTDPAIQKAVAWLVANQNPDGGWGESCQSDQKKTYVPLGASTPSQTAWATDALIAVSPKP
TAELQRGIHHLLTHNQANDWTTRYPTGGGRPGGTYFAYHSYRWIWPLLALSHYQAKYANM
>A0A426H4K5|squalene-hopene cyclase|EC 5.4.99.17|Peribacillus simplex|TrEMBL
MCLRGGTTLNQHVQLEMNRLIHRLKQDQSADGSWNYPFDTGITADAYMIILLKVLEIEDA
SLIEALVKRIESRQTENGSWRLFHDEKDGNLSVTIEAYYGLLYSGLRKKQDPHMRKAKQF
ILSKGGIKQAKMLTKMMLTITGQYKWPLLFPIPLEAILLPPTFFFSIYDLSVYGRVTMVP
LLLLGHKRFQIMSPNTPSLKDLYQTREERSEEHVWKEYRTDEYRSFFSKLQSGVKTLIGY
PDYLHSLALETTKRFMLDRLEPDGTLYNYFGATFFMIFALLSTGYSKKDPVILKAVSGLK
GMSCSVDGHTHIQLTTAHVWNTSLISYALQEAGLPSRDETVKSANQYLLSRQHYMYGDWL
IHNPDAVPGGWGFSDLNTMNPDVDDTTASLRALAGQMQARPDNLDSWQRGVAFTISMQND
DGGFPAFERESDPKWVHLIPSEGSNYLFTDPSTADLTGRTLEFLGNYTNLKKPGKVSKKA
VDWLLKDQEQDGSWYGRWGICYLYGTWSALTGMKAVGHSSEHPAIKKAISWLKKIQNKDG
GWGESCYSDIKQHYMPLGTSTLTHTAWAVDALIATSDKPTPEIEKGISYLTREAQKEDWT
NDYPAGQLMASVLYTHYHSYRYIYPLLALSHYRNKFMDA
>A0A846GVS9|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO1G6|TrEMBL
MQTQDRIVESGVTEAIANSQSYLLAQQYPDGYWWAELESNVTITAEIVLLHKIWGTDKQR
PLHKAEAYLRSQQQKHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDSALVRARDFILR
RGGITKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPEWFPFTIYEMSSWARGSTVPLLI
VFDQKPVFDIQPRINLDELYTEGADHAKFELPRNSDWTDLFVLLDDGFKLAEDLNLVPFR
KEGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPIVQRGLEAIDRFAIE
TPDSYRVQACVSPVWDTAWVLRGMVESGLEPDHPALVRGGEWLLQQQILDYGDWVVKNPQ
GKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLKQAAMARGLAWIASMQCKQGGW
AAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEMLGSCNLSIESQQLEKAIAFLIQ
EQETDGSWFGRWGVNYIYGTSSALSALSKVAPHSHQRSIERGAAWLVKCQNLDGGWGETC
LSYDDPSLKGVGISTASQTAWALIGLMAAGEATGNWAMDAIEMGVNYLVSTQQPDGSWDE
TEFTGTGFPSHFYLKYHFYQQYFPLLALGRYQMSVLS
>C7MXN7|squalene-hopene cyclase|EC 5.4.99.17|Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)|TrEMBL
MTDVLTRELSPNSTRDRVRSCVSSARQYLLSLQHEEGWWKGELDTNVTMEAEDLLLRQFL
GISDEQVTQETARWIRSCQREDGTWATFHGGPPDLSTTVEAYVALRLAGDAMDAAHLRKA
REYILDSGGIESTRVFTRIWLALFGEWPWSRLPVLPPEMMLLPDWFPLNIYDWASWARQT
VVPLTIVGSLRPTRDLGFSVRELRTGIQRRDLESPLSWAGVFHGLDSVLHRLEKLPLKPL
RKVALARAEQWILDRQESDGGWGGIQPPWVYSILALHLRGYPLDHPVLRKALDGLDGFTI
RHRTENGWIRKLEACQSPVWDTALAMTALLDSGTPPNDPALVRAADWILRQEIRVSGDWR
VRRPALEPSGWAFEFANDHYPDTDDTAEVVLGLQRVRHPEPHRVNAAVERATAWLVGMQS
SDGGWGAFDADNTRTLCEKLPFCDFGAVIDPPSADVTAHIVEMLAARGMADSESARRGVR
WLLEHQEVDGSWFGRWGANHVYGTGAVVPALVACGISPQHEAVRAAVQWLVAHQNADGGW
GEDLRSYVDRTWVGRGTSTPSQTAWALLALLAAGERGEVVRRGVEWLMAAQRPDGGWDEP
QYTGTGFPGDFYISYHMYRIVFPLTALGRYLGRGGDVGTG
>A0A5P9YZI5|squalene-hopene cyclase|EC 5.4.99.17|Nonomuraea nitratireducens|TrEMBL
MTTLGTPTTGETPAIRETPDALGTPGTLTGPITGPITGAEQALQAACDHLIGLRSAEGWW
KGELQTNVTMDAEDLLLREFVGIRTEEDTAEAARWIRSEQRADGTWANFHGGPADLSTTI
EAYAALRLAGDPPDAEHMRAAARQVRDLGGIEASRVFTRIWLALFGEWEWRDLPVMPPEM
IYLPSWFPFNVYDWACWARQTIVPLTVVTAYRPVRPLPFRLPELRTGLRPERARRGGWEA
AFGALDKVLHRYERRPARGLRRAAVRRAVEWIVARQEADGSWGGIQPPWVYSVIALHLAG
YHHDHPVMRKAIGGLDRFTIRDEKGRRLEACQSPVWDTALAVNALLDAGTPADHPAVTGA
ADWLLREEITRAGDWAVRRPALAPGGWAFEFDNDGYPDTDDTAEVVLALRRLDRTGIRPA
VERGVRWMTGMASRDGGFAAFDADNDRALITKLPFCDFGAVIDPPSADVTAHVVEALAKE
RPHSLALRRGVVWLLRAQERDGSWFGRWGANHVYGTGAVVPALVAAGVRPWHSSVRRAVA
WLEHHQNDDGGWGEDLRSYRDPSWIGRGASTPSQTAWALLALLAAGERSQAVERGVRWLV
GNQRPDGTWDEPYFTGTGFPGDFYINYHLYRLVFPISALGRYLRRDGTPAGPEAP
>A0A7R8RXI7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. KY75|TrEMBL
MTATTDGSTGAANLSAAPAGHPADTTTAADGVTAAADDVTAAARRAAERSVAHLLGRQDE
QGWWKGDLATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPSDL
SATIEAYVALRLAGDRPDEPHMARASAWIREQGGIAAARVFTRIWLALFGWWKWDDLPEL
PPELMFFPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPAEPNPPRK
LAPAASWDGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIIERQENDGCWGGIQPPAVY
SIIALHLLGYDLDHPVMKAGLASLDRFAVHREDGARMVEACQSPVWDTCLATIALVDGGL
RPDHPALVKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALR
RVRHPDPARLEAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSA
DVTGHVVEMLAVEGLGAHPRTRRGIEWLLADQEACGAWFGRWGVNYVYGTGSVVPALVAA
GLPAAHPSIRRAVTWLESVQNDDGGWGEDLRSYTEEKWIGHGESTASQTAWALLALLAAG
RRDSRAVARGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYG
DPFADRTGAAQGA
>A0A4P7WB61|squalene-hopene cyclase|EC 5.4.99.17|Acetobacteraceae bacterium|TrEMBL
MAKTKEQQTLKEVKPAFKIKSFLELLEKKLGAAQDALLKHQNKDGHWVFELEADATIPAE
YVLLEHYVDRIDPEKEEKIAKYLRDRQEEHGGWPLYYDGKFDLSASVKAYYALKVIGDSP
DAPHMRKAREAILRHGGAERSNVFTRILLALYGQVPWDAVPVMPVELILLPRKAFVSIWN
MSYWSRTVIAPLLVLAALRPLAINPKNVHIDELFRTRPSKIKDWIRGPYRSWWGYAFKAL
DVVLRKVEPFFPRRTRRRAIGKAIAFIEERLSEGGLGAIYPAMANVVMMYRALGVKDNHP
LAREAWDSIQDLLVEKNEEIYCQPCVSPVWDTGLASVALIEVFDGNDTVLKEETKKHLIE
AAEWLKERQILDVRGDWAVNTAKDIEPGGWAFQYENPYYPDVDDTAVVGIFLHRLDAKKN
SFAIERARKWVKGLQSTNGGWGAFDIDNDLDILNQTPFADHGALLDPPTADVSARCVSFL
AQVGKDEDIQSLERGIAYLRKEQEADGSWFGRWGTNYIYGTWSVLSAFNAAELPHDDAAI
QKAVRWLEKVQREDGGWGEDCASYEGAEPGSYRRSLPTQTAWALLALMAVGEVHSEVVQR
GIDYLLSTQNENGEWEESFHNAVGFPRVFYLRYHGYKHFFPLLALSRFKNLKENDIKSTS
WGI
>A0A7G7BE94|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces finlayi|TrEMBL
MTATTDGSTGAANLRAASASHPTDTTIAADDVLTAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPATIEATARFIRGEQLGDGTWATFYEGPGDLSATIEAY
VALRLAGDRPDDPHMARAAGWVREQGGIAGARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPSSPNPPKPAAPRASW
DGIFQQLDKVMHLYHKVAPRKLRRVAMNAAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMRAGLASLDRFSVWREDGARMIEACQSPVWDTCLATIALADAGLSPDHPAL
VKAADWMLGEEIVRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDA
ARIEAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGRAHHPGTRRGIEWLLAEQEAGGAWFGRWGVNYIYGTGSVVPALIAAGIPASHP
SVRRAVSWLESVQNDDGGWGEDLRSYQEEKWIGHGPSTASQTAWALLALLAAGERDGRAV
ERGVTWLAATQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRA
PVRKGA
>A0A831TSB6|squalene-hopene cyclase|EC 5.4.99.17|Armatimonadetes bacterium|TrEMBL
MTPPFESSTTAPIVASPADALRGAIARAAEWLLARQRPAGEFVGELEGDTILESEYLLLR
YFLGCLDDRRKRQLANYLRATQLPDGGWPLYPGGPPNVSNSVKAYLALRLAGWSPEHPDL
VRARRVIRELGGVTACNTFTKIYLALFGQYDWDGTPVVPPELVLLPRWFYLNLYAISSWS
RTILVPLAIVCSYRPYCPLPEGIDLDELYVGPRHGPAVRLRWDRRLLSWRNFFLVVDRAL
HHLERIGMKPWRQRALREAERWMLARFERSGGLGAIFPPIVNALIALRCLGYPDDDPAVQ
SQWREIEAFEIVEDDRMRLQPCVSPVWDTALSLMALAEAGIGGENEPRVARAVEWLLSKQ
TRYPGDWSLARPGVEPGGWYFEYENEFYPDVDDTAAVLMALARAGGVERGRLRAAVIRAL
RWVFAMQCRGGGWAAFDVDNDRMIFTEIPFADHNAMLDPPTADITGRVLEMLGHYGYTTA
DARVARAVAFLLADGVLPSNEGRGYVLRRILRRAVRHAWLLGRREPTLVEVVDEVADRMG
DVYPELRAQRDHLLRTTRLEEERFLETIDAGAARFDELAPELPPEMHAAIDAGRAPRPVI
PGADAFRLYDTYGYPLDLIELMARERGYVVDREGFEAALEEQRERSRRAREAAAPAAELA
AGWEELEPGAEQEFVGYQTTTVETDIIAYRREDGRLALQLRENPFYAEAGGQV
>D8K5F7|squalene-hopene cyclase|EC 5.4.99.17|Nitrosococcus watsoni (strain C-113)|TrEMBL
MTRALRQAPESAGAIDIATAAPATETLHQDTRPRELGGAITAARDALLKLQQADGHWCFI
LEADCTIPAEYILWTHFTGELELEIERKLAARLRAKQASHGGWPLYEGGDLDISCSVKVY
YALKLAGDDPNAPHMRRAREAILAQGGGARANVFTRLALAMFNQIPWRGVPFIPVEIMLL
PRWFPFHLSKVSYWSRTVMVPLAILYSLKAQAQNPRNVHVQELFTVPPEQERHYFPVRSR
LNKILLSVERTARLLEPLIPSMLRRRALKKAETWFTARLNGEDGLGGIFPAMVNAHEALI
LLGYSPDHPRRVQAKKALQNLVIEEQSSASCQPCLSPVWDTGLAALALQETEGGHTTAPV
IRALDWLKERQILEQPGDWQEQHPHLKGGGWAFQYNNSYYPDLDDTALVAWAMDQAATPE
HYGEAIGRASDWLCGMQSRNGGFAAFEADNTHYYLNEIPFADHGALLDPPTADVTARCIV
LLGRLKAPQYAEPLQRALDYLRQEQEPNGSWFGRWGTNYIYGTWSILTALEQAGIDPQEG
FIRKSVEWLKQVQRLDGGWGEDNYSYFDSSLAGHYQESTPVHTAWALLALMAVGEANSEA
VKKGITYLLQVQQEDGLWDHPAFNAPGFPRVFYLKYHGYDKIFPLWALARYRNHLNRQC
>A0A7K2D5F8|squalene-hopene cyclase|EC 5.4.99.17|Acidimicrobiaceae bacterium|TrEMBL
MDDHQAHQSVREAVERTQQYFLRTQRDDGCWWGELESNPTIEAEYIMLTRFLRSDEGDRI
PRVAADIRRRQQPDGSWRMYYGAPGDLSTTIECYFALKLAGDPPDAPHMAQARAFIIENG
GIPKSRVFTKIWLALFGQLDWRATPSMPPEIMLLPKWAPFNIYRFSSWARATIVPMTIVL
TLKPTRPPPAGAGIEELRRDGPEALAVSRFKPNPLSVQGGFLLMDRALRLWRGLRLVPGR
RRALRAAVDWIVTHQEGDGSWGGIQPPWVYSLIALSALGHPLDHPVLAKGLQGFRNEWSL
PSPDGAALRVQACLSPAWDTALAMRGLMDSGVSPDHPAIQRAAEWLVGKEVRYAGDWAVK
RPNLEPSGWAFGFDNVNYPDIDDSSVIVANLALTNLADRASDAAKEATIDRAVDWLTGMQ
SSNGGWAAFDHNNDSRSVTKIPFADFGEVLDPPSADITAHMLEMYGILGYSRWHPAVRRG
LHYLWQQQEPDGSWFGRWGVNYLYGTGAVLPALEALGVDMAQPAVRKAVQWLVDTQNPDG
GWGETCESYVDPTLSGQGDSTASQTAWALIALIAAGEAVGEPVTRGIEFLVATQQADGTW
DEPQFTGTGFPGYGHGDRPTKKGAPADSLQGAEMGAAFMINYHLYRNYFPLWALGRYLSA
VAPRVAQAVPLGRTETETDKSPNAIQEVIDLPTGPSRRARRQRSPMGSHRAVHRPTAPPP
>A0A7X0IHT9|squalene-hopene cyclase|EC 5.4.99.17|Sphaerisporangium rubeum|TrEMBL
MTQRTITAAADEASAGPLATAAGHALAAACDHLIGLRDPAGWWKGELRTNVTMDAEDLLM
REFLGVRSRRDTDEAARWIRREQRPDGTWATFHGGPGDLSTTIEAYTALRLAGDPPGEPH
MRAAAAFARRGGGIGSARVFTRIWLALFGQWRWDDLPALPPELVLLPQWCPLNVYDWACW
ARQTIVPLTVVAAHRPVRPLPFDLAELRTGRPALRGRHRGVIGAVDRLLRRYDRRPLPGL
RRAALRRAMEWIVARQEADGSWGGIQPPWVYSLIALHVSGYATDHPVMRRGLSGFDRFTV
RDEQGRRMEACQSPVWDTALAVTALLDAGVPADHPAVTQAAVWLLGEEVRGPGDWSVRRP
GLAPGGWAFEFDNDGYPDTDDTAEVVLALRRVPLPGVRPAVDRGVRWMAGMACRDGGFAA
FDADNTRELIRRLPFCDFGAVIDPPTADVTAHVVEALAAEPPADPEVLRRGVRWLLRAQE
PGGSWFGRWGANHVYGTGAVLPALAAAGVPAAHPAVRRAVTWLERHQNPDGGWGEDMRSY
RDPRWIGRGHSTASQTAWALIALLAAGERSPAVDAGIGWLVRTRLPSGTWDEPYYTGTGF
PGDFSINYHLYRLVFPIMALGRYLRGNGAG
>A0A5N8YTJ9|squalene-hopene cyclase|EC 5.4.99.17|SAR202 cluster bacterium AD-804-J14_MRT_500m|TrEMBL
MTEFADKIFNELKSEVDWTIQRCQQYMLQIQYDEGFWWGELESNPTMEAEYLMLSYLLEL
EDQDRWTMISNHILSRQQDDGSWAQYFNAPGNLSTSVECYFALKLAGIPANSPKMIKAHN
FIISQGGVQKTRVFTKIWLAMLGQYDWARLPTIPPEIILLPNWFPFNIYQFSSWARATIV
PMSIILAERPCRPAPQWATIPELYPHHEQQADHYRSQHKTIFSLGTILHGIDWLLRQYNS
SPLKPGREYSKKLAGQWILAHQEADGSWGGIQPPWVYSLIALKHLGFSLDHSAMKIGWQG
FETYGIQEGDTWRVQACISPVWDTCLTQIAMLESGISPNHPAMERSTRWLIDKQILQGGD
WQIKAPQTPPAGWAFEFANNNYPDIDDVSEVIMALHLARLPETDDLSRKIAIKRAVTWLL
ALQSSNGGWAAFDKDNNHHYLSKIPFADFGEILDPPSADVTAHIMEALGKLGYDKTTPAI
NKAYQFIRTEQEDDGSWFGRWGVNYIYGTGAVLPAMKAIGEDMSQPYIQRALEWLRSHQN
SDGGWGESCGSYVDPALKGKGDSTPSQTAWALLSLISAGVPHDISTIRGLQYLCAEQNEN
GAWDEPYYTGTGFPGYGLGERFKKLPSQGQQGYQGLDMEGAFMINYHLYRNYWPLTALGR
FQKSMTE
>A0A7Y3P8V3|squalene-hopene cyclase|EC 5.4.99.17|Elusimicrobia bacterium|TrEMBL
MLKNLVSGWLAEGRRYRKPQDWADHVRPDAAAAAEGPLPEALTQTIRRSQEALLRQQNPE
DGFWCGPIFGDTTIDSDTIMLLNFLGRGNSIKIRRIANHLLNKQNPDGGWPIYDNGPSEI
SATVKAYWALKFAGHSPQEPCLESARKCIKRLGGIHKVNTYTKFYLALFGQYDWRGVPSI
PPEIMLFPNWFYFNLYEMSAWTRPIVVPLAIVWAFQPAVPCPAHATIDELFPDTRRHVPL
SEAVGPHRLVSWTTFFLMWDSFLKGMEGRGGHWIRVWALRLAEDWILERLQDSDGPGAIY
PPITNAIMAMKCLGYPDTDPRLVSLLQELDRLEHPGTDSTRYQPSRSPVWDTAITMIALA
ESGLDRAHPALVQACQWTISKEIKVRGDWAVTNPNGPTGGWHFQFNNVFYPDVDDTAMVL
LALRHVHLEDVNATIREKSFLRGLNWILSMQSSTGGWAAFDKENTKVVLTKIPFADHNAM
IDPPTSDITARVLELLGCVGYDGSYAPVNKAIKFLKAEQESDGSWYGRWGVNYIYGTWQA
LRGLAAIGEDMRKPYVQRAAAWLKSVQHADGGWGETCETYENPAAKGRGPSTPAQTAWAL
MGLIAAGVDDESVRRGVAYLTGTQRVDGTWDETEFTGTGFPKVYYLEYTMYRNYFPLQAL
GNYRKALLSGRARA
>A0A7Y9GFN6|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura citrea|TrEMBL
MTTTEPTTGTTPATAPPPAPGPTPAPGSPVVAEPPGPGGAGRIRTAAQALKAARDHLLLL
QSPEGWWKGELQTNVTMDAEDLLLREFLGIRDDADTTETARWIRSQQAADGTWANFHDGP
PDLSTTVEAYVALRLAGDPPDAGHMIRAAAFVRGGGGIPATRVFTRFWLAMFGRWSWDDL
PVLPPEMMFLPRWFPLNVYDWACWARQTIVPLTVVAALRPVRPLPFALDELYPGYDVPPA
RRRGLSGWDAAFGALDKALHVYERHPAKGVRRAALRRAAEWIIARQERDGSWGGIQPPWV
YSLLALHLLGHGLDHPIVRRGLDGLERFTIRDDRGRRLEACQSPVWDTALAVNALADAGL
PAGHPALERAAEWLIGEEVRGPGDWSVRRPDLPPGGWAFEFDNDCYPDTDDTAEVVLALG
RARLPQAEPAIERGVRWMAGMASRDGGFGAFDADNTRALCRRLPFCDFGEVIDPPSADVT
AHVVEAMSHRGMADSLVVKRAVVWLLKAQEPDGSWFGRWGANHVYGTGSVVPALIAAGVR
PGKPAIRDAVGWLERHQRDDGGWGEDLRSYRDRTWIGHGASTPSQTAWALLALLAAGERG
PAVERGIRWLVEHQRPDGTWDEDHFTGTGFPGDFYINYHLYRLVFPLSALGRYLKEIS
>A0A7X7VIU3|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia bacterium|TrEMBL
MEVASLRQSRAEGNPRQTDFGFKPRVELEAAIERSQRYLLGEQKAEGYWIGELLVDATLV
SDMVAYHHWNGQVDPQWERKAVNHIFSKQLPDGGWNIYHGGPAEVNATVKAYLALKLAGV
PVTDPRMLRAREVAVNLGGVPRMNTFSKLYLALLGLFPWEYVPTIPCEVILIGKWFYVNF
NEMSSWSRSMFVPLAIINHFKPTRKLKSGVKLDELYPEGIHGRDLALAPDPERITWRNFF
LWLDRVHKFAEWFAQHGIHPFRKRALRKAEQWMLERFEGSDGLGAIFPAMLNSLIALKAL
GYPDDHPQVVRAAAELKKLEHETEQSVRIEPCLSPVWDTAIVSICLRESGVPADHPALKR
AAEWLMAREIRFRGDWIYKNPAKVEPSGWVFEFDNKWNPDVDDTAMVLLALRLVATDDRQ
KRDECFQRGLTWMMTFQCKDGGWAAFDKDCTKGVLEKVPFADHNAMLDPECADITARILE
LLGYEGWSVEHPQVQRALRFIRERQEEDGSWYGRWGVNYIYGTWQVLRGLRALNLDMRQP
WLLKARDWLESVQHEDGGWGERCNTYDDPVFKGQGPSTASQTAWAVMGLCAFGDPERPSL
QRGIEYLVRTQNADGSWTEHETTGTGFPKVFYLKYDMYRNSWPLLALATYRQLLAPDSAA
RRA
>A0A7V7BPY0|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia bacterium|TrEMBL
MSATVPNRAGAEARSEVALPPQDLKTAILRSQEYLLSLQKPEGYWVGELIVDSTLVSDMV
AYHHWDDSVDPEWQRKAVNHILSMQLPDGGWNIYYGGPPEVNATIKAYLALKLAGVPVTD
PRMLRAREVALSLGGVPRMNTFSKLYLALLGLFPWEYVPTIPCEVILIGKWFHVNFWEMS
NWSRAMLVPLAIINHFKPTRRPRNNVTLDELYPQGFHERDLALPPDPDRLSWRNFFLWLD
RLHKFAEIFAQHNIHPFRKRALRKAEQWMLERFEGSDGLAAIFPAMLNSVIALKALGYSN
DNPILKREWEQLKRLQHETENDVRIEPCFSPVWDTAITLVCLRESGIPADHPQLKKAAEW
LMSKEIRFRGDWQYKNPAKVEPSGWVFEYENKWNPDVDDTAMVLLALRQVPTDNPKKRDE
SFQRGLKWMMTFQCKDGGWAAFDKDCTKNILEKVPFADHNAMLDPECADITARILELLGY
EGYGIEHPQVKDALAFLKSHQEKDGSWYGRWGVNYIYGTWQVLRGLRAMRIDMTQPWILK
ARDWLESVQHEDGGWGERCNTYDDPVFKGQGPSTASQTAWAVMGLCAFDDPDRPSIRRGI
DYLIRTQNSDGSWTELETTGTGFPKVFYLKYDMYRNTWPLLALATYERIRKARNAQREAD
FEKAVGLARPALTSTATSAVP
>A0A7V6Z1P6|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia bacterium|TrEMBL
MAQITENIASVTPSARSGRVSFPSEEALETAISRAMEWLERAQQREGFWVGMLESNCCME
AQWILAMHFLGVKDDPKLPGVIRAILREQRPDGSWEVYHQAPMGDINTTVECYAALRSVG
FKPDDEPLRKAREWILSNGGLKRTRNFTRIWLALIGEWPWEYTPVVPPELILLPTWMPFN
LYWFASWARATIVPLAIVSARRPVRPLPPDRRLDELFPEGRDRFDYSIPMTKQGFWATFF
WLNERILHVYGMLPWQPGRETCIRLCLEWIIRHQDADGAWGGIQPPWIYSLMALHTEGYP
LDHPVMHRGLDAWNHHWSFERDGATYLQASESPIWDTLLTLQGLLDCDATPDSFPAMLPA
IEWILDKQILVKGDWAMTVKGVKCGGWAFERANRHYPDLDDTAVAITVLAQLRELVSPPL
RDRIQTAIQRAEDWVRAMQSSNGGWAAFDKDNNKWILTRIPFCDFGEVLDPPSADLTGHK
LEALGLLGYDLRDPAVKRAVDFIMAEQEPDGSWFGRWGVNYIYGTGLVLPGLRAVGFDMN
DPRIRKAADWLVSKQSPDGGWGESCASYMDENWRALGPNTPSQTAWALMGLLAVGGHDYD
AAIARGVEWLLRHQRNGTWDEPHYVGCGFPGYGIGERIDLKKDTARLAQGKELARGFMIN
YNMYRHYFPMQALGRARRHFRGG
>A0A7V0V1L9|squalene-hopene cyclase|EC 5.4.99.17|Anaerolineae bacterium|TrEMBL
MRSVRAAGSRHRPPAAGGAWRSLVGCEPGQGRCRSVALRPRLLADVGREDAVSARPLYHD
RQLLAEAVRDAVRRSQDYFLRTQHPEGYWWGELESNVTMAAEYLMLTHILGVADAERWRK
VANYLRREARPDGTWAIYYGGPPDLNATVESYLALKMAGAPADDPLLEKARAFVLSRGGV
PRVRVFTKIWLAMLGLWDWRGVPVLPPEFMFLPTWFPINLYEFASWARATIVPILIILDR
RPVWPVPQHARIDELFPVPPSHLDYRLPPPQRLLSWKGLFWGLDHALRAYGRVAFRPLRE
AAIREAVKWIIARQEADGSWSGIQPPWVYSLIALKLLGYPLEHPVMRKGLEAFEGAFRVE
DDTVYYPQACISPVWDTALAMIGLLDSGLPPDHEALVRAGRWLLKEQIFTGGDWQFKAKG
VEPGGWAFEFDNDIYPDVDDTAEVMMALHRTRLPEEGRKARALRRGLEWVLGMQCRDGGW
GAFDKDNTQRIITHIPFCDFGEVLDYPTEDVTAHVVEMLGLLGYRADFPPVRRALAFLRR
KQDADGPWWGRWGVNYIYGTGAVLPALQAIGEDMRRPYVRRAVRWLLDRQNADGGWGESC
DSYADVSLKGQGPSTASQTAWALMALLAAAADDPDGEAWESIGRGAAYLVETQEEDGTWH
EPYFTGTGFPRDFYINYHLYRNYWPLMALGRLHRLLST
>A0A6G2NSD0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4925|TrEMBL
MTATTDGSTGAANLRAVTFGDPIEPTTDTDDVLAAARRAAGRSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETVQAAARFIRGEQLGDGTWNTFHGGPPDISATIEAY
VALRLAGDLPDDPHMLRAAGWVREQGGIAASRVFTRIWLALFGWWKWEDLPELPPELMFF
PSWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPEHPAPPRPLAPAASW
DGVFQRLDKALHAYHKVAPRRLRRIAMNAAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLEHPVMRAGIASLDRFTVWREDGSRMVEACQSPVWDTCLATIALADAGVPPDHPAL
VRAADWMLGEEIVRPGDWSVRRPQLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDQ
PLVDAAIERGVRWNLGMQSRDGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLATDPRTRRGIQWLLDEQEASGAWFGRWGVNYIYGTGSVVPALIAAGLPASHS
SVRRAVSWLESVQNDDGGWGEDLRSYREEKWIGHGASTASQTAWALLALLAAGERESRVV
ERGVTWLAETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFATAG
TGTAPGREA
>A0A8J6X375|squalene-hopene cyclase|EC 5.4.99.17|Nostoc muscorum FACHB-395|TrEMBL
MQTQDRVKVNQIAEAIAASQQYLLSIQNPAGYWWAELESNVTITAETVLLHKIWGTDETR
PLHKVEAYLRQEQRQHGGWELYYGDGGELSTSVEAYMALRLLGVPASDPAMIRAKAFILQ
RGGISKTRIFTKLHLALIGCYNWRGIPSLPPWIMLLPKAFPVNIYEMSSWARSSTVPLLI
VCDRKPVFITDPTINLDELYAEGVDRVRWELPQSGDWTDLFLTLDQGFKWAESLNLVPFR
EEGIKAAEKWILERQEATGDWGGIIPAMLNSMLALRCLDYDRSDPIVERGLQAIDNFAIE
TENSYRVQPCVSPVWDTAWVMRALVESGFAPDHPAVVKAGEWLLQKQILDYGDWAVKNRQ
GKPGAWAFEFDNRFYPDVDDSAVVVMALHLAKLPNEKIKQAAIARAVNWIASMQCKPGGW
AAFDLDNDQDWLNSIPYGDLKAMIDPNTADVTARVVEMLGACDLSIDSDNLERSLTYLLR
EQESEGCWFGRWGVNYIYGTSGVLSALALIDPQRHKLSIERGAAWLVGCQNLDGGWGETC
RSYDDPSLKGKGNSTASQTAWALIGLLAAGEATGKFALEAIEQGIGYLVATQKSDGTWFE
ADFTGTGFPCHFYLKYHLYQQYFPLIALGRYQAVLR
>A0A661XQD0|squalene-hopene cyclase|EC 5.4.99.17|Bacteroidetes bacterium|TrEMBL
MDTITKKMCETDFNDQNMTSQVDNAIDSALVSIVEQQDPKGFWCYELEADITIPSEYILM
MHYLGDVEKGIQSKMANYIRKRQQENGGWPLYKGGITNISCTVKAYYALKLAGDDIDSSH
MILAKRAILERGGAAKSNVFTRIMLAMFEQVPWRAIPFIPVEIMLLPKWFPFHISKISYW
SRSVMVPLFILYSLKATAKNPEKIDVRELFETPPEKERHYFPTRSILNKLILIMERIAFN
IQWLIPGFVHKMALNKAKDWFIVRLNGDSGLGAIFPAMVNAYESLLLLGFDKDDEIVKTA
RRAIDLLIVEKEEEAYCQPCVSPVWDTLLAAQALLETKDERSIEPIQNGMKWLQEKQIVD
GNADWRKVRPNLAPGGWAFQFDNAHYPDLDDTAFAGLAMVKTDFNKYRKNIKLAADWIAG
MQSMDGGFASFELDNTQYYLNEIPFADHGALLDPPTTDVTARCIMFLSSVVAKYPEYQNA
IDKGLDYINREQEENGSWFGRWGTNYVYGTWSVLMAFEEMKIKSNDERVKKGAAWLKSVQ
REDGGWGEDNDSFETFGKPGLGYKSAAFQTA
>A0A4V5MLF3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces piniterrae|TrEMBL
MTATTDGSTGALPPRAPSASDATAENTARREERRPAAPDAAPQDTAAAARRATALATEHL
LSLQDPAGWWKGDLETNVTMDAEDLLLRQFLGIQDPELTEAAARFIRGEQRADGTWATFY
GGPGELSATIEAYVALRLAGDAPDAPHLARASAWIREQGGIAAARVFTRIWLALFGWWKW
DDLPELPPELIYLPKWFPLNIYDFGCWARQTIVALTIVSAKRPVRPAPFALDELHTDPRN
PNPPRPLAPATSWDGVFQRLDKALHVYHKVASRKLRGAAMRSAARWIIERQENDGCWGGI
QPPAVYSIIALHLLGYDLDHPVLRTGLKSLDRFAVWRDDGSRMIEACQSPVWDTCLATIA
LADAGLPADHPQLVKAADWMLDEQIHRPGDWSVRRPRLPSGGWAFEFENDNYPDIDDTAE
VVLALRRVAHPDPGRVDAAVQRAVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEV
IDPPSADVTAHVVEMLADVGRTHDPHTRRGIDWLLAEQEPGGAWFGRWGTNYVYGTGSVL
PALAAAGIPGSHPAVRRAVGWLERVQNDDGGWGEDQRSYQDKKWAGRGESTASQTGWALM
ALLAAGERDGEAVRRGVRWLAETQRPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTAL
GRYVNGGPAGAPLGA
>A0A6L7TU55|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MGSMLDGLNKLAELAEKVKRAISHSHRYFRDSQHPDGYWWGELESNPTMEAEYLMLSHFL
GRKNPERWRKVANYILGKQQNDGSWGQYYEAPGDVSTSVECYFALKLAGHPADSPELTRA
REFIISRGGVPKTRVFTKIWLALFGQWEWSGTPNLPPELMLLPSWAPFNIYEFSSWARAT
IVPMSIILTERPYCEIPDSARIDELYPNGREATDFSLSVPDDWISRGLFTLDRLMNLYRK
VPMQPLRGLARQRAIQWILEHQEADGAWGGIQPPWVYSLIALHHAGEEEFADALDKGFDG
FDSFAIEDEDTCSVQACISPVWDTCLAQLALLESGVADNDPMVQLSSRWLMDNQILAEGD
WQVRAKDTPPGGWAFEFHNEKYPDIDDSSEVIIALALARLEGGDETDRQEAIRRGVEWIE
GMQSRSGGWAAFDKDNDRWYVARIPFSDFGETLDPPSADVTAHILEMYGRLGYSMDHPPV
QRGYQYLLREQEEDGPWFGRWGVNYIYGAGAALPAFEAIGEDMGQPYVRRAVEWLMAHQN
DDGGWGECCGSYVDESLRGVGTSTASQTAWALLALIAAGEAGSEACYKGISYLLDLQQPD
GSWDEPYFTGTGFPGYRVGQPPKGMPKPGEADYQGLDMPAGFMINYHLYRNYWPLLALGR
FARAIEQARPRGSGERQPTVSEDHRKKEPRQLEGAASG
>A0A7V2JNJ7|squalene-hopene cyclase|EC 5.4.99.17|Acidiferrobacteraceae bacterium|TrEMBL
LFLYVERTARLFEPMVPNWLRNLSIKKAEQWFLERLNGEDGLGAIFPAMVNAHEALAWLG
YKEDHPYRITTRKALQKLLVVGKDSAYCQPCMSPVWDTALAALALQETGDKKYKSAIKKS
LDWLKGKQLLNNDGDWSMQRPNLRGGGWPFQFANNHYPDLDDTAAVAWAMCQENDEDYRE
TISRAAEWIAGMQSNNGGYAAFDADNTRYYLNEIPFADHGALLDPPTSDVSARCLAFLSM
VDEPGFEMANKRCLDYLRTEQEVDGSWFGRWGTNYIYGTWSVLTALEKAGVSMDDAMVHR
AMQWLKQVQRHDGGWGESNDSYMYPQSAGENSTSTTFHTSIAMLGLMAAGEADSMAAQRG
AEYLLHTQLPSGCWHDPGFNAPGFPRVFYLKYHGYDKFFPLWALARYYKLRSKQVR
>A0A4R5BV49|squalene-hopene cyclase|EC 5.4.99.17|Saccharopolyspora karakumensis|TrEMBL
MPSQGAARADARTAALAARDHLLSLQSPEGWWKGELETNVTMDVEDLLLRQFLGIRTSAE
TAQTARWIRSQQREDGTWANFHGGPGDLSTTVEAYAALKLAGDDVDAPHMRAARDWILAG
GGLEGTRVFTRIWLALFGEWSWDDLPAMPPEVVLLPEWCPLNVSDWACWARQTVVPLTVV
CTLRPRRDLGITLRELRTGRPAEPPKREWSWGYGFHALDRVLHRYHRRPVKSLRTHAMRR
AAEWIVARQEADGSWGGIQPPWVYSILALHLLGYPMDHPVIAKGLGGLERFLIREQTPEG
TVRRLEACQSPVWDTILGVQALRDAGVPADDPSLRRAVDYLLAEEIRVKGDWSVKRPELP
AGGGWAFEFDNDGYPDIDDTAEVLLALNRVEHPDSDAVRGALARGVRWLRGMRSKDGGWG
AFDADNTRQLVRKLPFCDFGEVIDPPSADVTAHVVEALAVLGEQDEVLRGGVKWLLSNQE
RDGSWFGRWGANHVYGTGAVVPALVAAGVDRQHRALRDAVRWLENHQNDDGGWGEDLRSY
DDPQWIGRGTSTPSQTGWALMALLAVGRHDTDAVRRGIGYLARSQRADGGWDEPQFTGTG
FPGDFYINYHLYRVIFPLTALGRYLRDGE
>A0A532CV82|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp|TrEMBL
MNIIKALFNRLSDSLLSTVQGRLDPATELTPGASLRLVSDKPVILASLDSSAARRPIGHA
VSQPDAVDDAIRRSQSWFFNRQHAEGYWVAELEADTTLTSEYVMLRRFLDRVDPDREVKA
VRYLQATQLQDGGWPIYYGGPAEISASVKAYFALKLCGVSADEPFMVRAKERILAMGGVL
QANVFTKITLALFDQYDWEGVPHMPVELMLLPKKFYFSIYAISYWSRAVLIPLLIVFAHR
PVCRIPCEQGIDELYPIPRLEVRYWKYPPFNKDQAWFTPHNFFVALDVMLKLYDRMPMRA
LREKALHKAACWMVDHLKGDGGLGAIYPAMANSIMALQCLGYDANDPLVVKALREIEALE
VYDSTMVDGESVPTLHLQPCFSPVWDTALLMNALVEAGVPQDHPALQKAGRYLMSRQTKA
VGDWIISSPNAEPGGWYFQFENESYPDVDDSAVVIMALSKLKIPGHEDELNESIGRGMRW
VLAMQGSDGGWGAYDKDNNRVVFNYIPFADHKALLDPSTSDLAGRCLEMLGALGYDMTHP
AAGPALAFLKKEQEEDGSWYGRWGVNYIYGTWSVLAGLRAIGEDLSAPYIRRAVTWLESK
QNPDGGWGESCLSYRDDSEVHGKGESTASQTAWALMALMSADAVDSFSVARGVQFLLRWQ
MKDGSWEEISHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRSRGKIRADELRHHIQGT
DLYRSKH
>A0A7W1UHD6|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirales bacterium|TrEMBL
MLTSTRHLILETAIDLLGRDGASALTLEHVAREAGLSKGGLLYHFEGKEQLLVGLIELLI
QDLDRKQVGDFLTNSIYEEQPWTALDTDAVENPTNHRSLQGHEIASILMAALAINPHLLE
PIRERYQNWQSIFLANTVDPTRSLVGRLAAEGLWFSEALGLAPPTREQRAALVLEIQSHT
QPGESMREPSASITPTQPKNAFAELASFKSHVEELERQAYQPTQTSARALLAKQNPQGFW
QGDLTADTTLESDYVLLLLWLYPPEAGAWKPEIQIKIDKAMRTILDRQLSDGGWDIYSEG
PAEVNATTRAYVALRVGGHDPDQPLMQRARECILALGGLQATNSYTKNNLSMFGLFPRKY
TPSVPPELVLIPGNVLYEISSWSRAIVVPLSILQASGVQRKVPGNWTVDELLVPNRKLTF
PKKDPFSLMFHQVDKILKLWEKRGFKDIRAKAIREAEKWMLDHMRFTDGLGAIFPGMMYA
LMAMDALGYERDHPDFIDTLGQLEGLILEKEGALQFQPSLSPVWDTAISMFALGELGIGE
PEAMQRAADWLLSKEIRRKGDWSVKRPDLQPGGWPFQFANELYPDIDDTAMVLLALEHAK
ASDPDRQTRAESRAINWLFGMQSSDGGWAAFDVDNTWALLNKVPFADHNAMLDPSCPDIT
GRVLEALCRRDYTHQHPAIARAVQYLLVHQQANGSWDGRWG
>A0A7V8W7M6|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirales bacterium|TrEMBL
MKLLKSLIIRLSDSLLASMPRRLKVSSRLRDMPMLRLVSDNPHPVVHPDPTIRKPAASVG
HSEFIDEAIQRSKSWLLKRQHAEGFWMAELEADTTLTSEYLMLRRFLNLVDVEKERKAVR
YLTATQLADGGWPIYYGGSSEISASVKAYFALKLAGVSQDEPFMVRAKDDILAKGGVAAA
NVFTKITLTLFDQYDWRGIPSMPPEIMLLPKWFYFSIYAISYWSRTVLIPLLIVFAHRPV
CRIPREQGIDELYVQPRHLMDYREVPPLHKDQSFFAWRNVFITLDRLLKIYDRMPIRSLR
DAAVQRAAEWVLARLHGGGGLGAIYPAMANSILALRCLGYGVDHPLVAKALREIEALEVY
GSVGTAQGRIEAMHLQPCVSPIWDTALFINAGVEAGLPQDHPALVKGGAWLVARQTQKVG
DWKVSAPTAKPGGWYFQFENEMYPDVDDSAVVLMALAKLQLGNRQTQQQSMERGYRWVMA
MQGSDGGWGAYDKDNNKMVFNLIPFADHRALLDPSTADLTGRCLEMLGALGYDRSHTAVR
PALEFLRRDQEEDGSWYGRWGVNYIYGTWSVLAGLRAIGEDMSAPFIQRAVTWLESTQNA
DGGWGESCLSYADKAHAGRGDSTPSQTAWALLALLSAGMSDSISVVRGVNYLLRHQREDG
SWEETRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNIRTRGRARADELRLAAFEAGLFR
SDH
>A0A3A9WT41|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces radicis|TrEMBL
MGHRGARRTPPRRVPHGRRDPSRWGRATTGDRRPTSVLPEGSARGTRSAQAPRTARTAPV
CPPIGPRAWGAGRPMNDIHATELRATDIHTHKVLARGIDNLLARQHDDGHWYEGPHTNVS
AESADIITRHCLGVADTTVLERTARRVRRGQRDDGSWPMFPGGPGHLSVTAEAYVALRLS
GDRTDEPHLRAAAEFCRRHGGLDAARTETHFWLALLGIRGWDRVPPVLPEQILLPAGVPV
AVRSLGVWSRHLLTPLSVIAARRPVRPAGFDLPELRDPASPAEAARPGAAERVMGAYHRH
PLRPLRNRALARAELWLLRHQQANGSWFHVFLFSALGTLALKALGHTAESNAYRAALTAL
DGFGETVETPDGVERRIVPCPGAVWDTAYSLLALADAGVEPTHPAVGRARAWLVATQSAS
GGDWQRDRPEVPPGGWPFSPGLNAFPDVDDTAVAVTALTRLRAAHEEPPPAEAEAVEAEA
VERGRGWLVGLQSRGGGWAAYESGDLSRLTELSQRLPYNDHGPMLDVPVADVTGHVLEAL
GPGASAAAGARWLLAQQEPDGSWFGRWGVNHVYGTGSAVPGLVAAGVDPGDPRVRRAVDW
LLEHQNADGGWGEDCRSYEDRAHRGRGPSTPSQTAWALLALHAAGVGADDERVRAAFAWL
GESQRPDGSWHEEVFTATGQPGEIYFSYPAIVQAMPVIALGRYLAPREPAEPAEPTGRPE
TRVAAERGNDRGAE
>A0A0U5BAA6|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter senegalensis|TrEMBL
MAADGSAFSDAPVSKETLDRAVTNAHAALGKRQQADGHWVYELEADATIPAEYVLLEHYL
DRIDDALEQKIGNYLRRIQSKDHGGWPLYHNGKFDLSASVKAYFALKAVGDDINAPHMRR
AREAILDHGGAERTNVFTRCQLALFGDAPWRATPVMPVELMLLPRKAFFSVWNMSYWSRT
VVAPLLVLAALKPIAINPRQIHVRELFVTPPEVVKDWIRGPYRSVWGRVFKGLDTVLRPV
LPFIPTQTHDKAIKAAVDFIEPRLNGEDGLGAIYPAMANVVMMYRALGVPDEDPRAVTAW
KAVQKLLVIKDDEAYCQPCVSPIWDTGLSGHAMLEAASGPNGVAPEETLTELRKASAWLR
DKQILDVKGDWAINKPDLAPGGWAFQYGNDYYPDVDDTAVVGMLLHRESDPANAEALERA
RQWIIGMQSTNGGWGAFDIDNNKDLLNHIPFADHGALLDPPTADVTARCISFLAQLGHVE
DQAVIDRAIEYLRKDQEEDGSWFGRWGTNYIYGTWSVLCAFNAAGISHDDPAVVKAVEWL
RSVQGADGGWGEGCESYEGGAHGTYGESLPSQTAWATLGLMAAGRRDDPAVAKGMAWLAE
QQDENGEWHEDPYNAVGFPKVFYLRYHGYKQFFPLMALARYRNLESSNTRRVAFGF
>A0A8E1W6P2|squalene-hopene cyclase|EC 5.4.99.17|Amycolatopsis echigonensis|TrEMBL
MTQTVPRTSAPAARTAADTVAAAVEFLRREQDRAGWWKGELATNVTMDAEDLLLRHFLGI
LTPQIAEESARWIRSQQRGDGTWANFPDGPADLSTTVEAWVALRLAGDPADAPWLSSAAE
WIRGHGGIEATRVFTRIWLALVGQWSWDELPSLPPELIFLPSWFPLNVYDFACWARQTIV
PLTIVGTFRPVRKLPFDVSELRTGKRPPKTRAPWTWDGVFQNLDTALHAYAKLPLNPVRK
LAMKQAAEWILARQEADGSWGGIQPPWVYSILALHLLGYPLDHPALKAGIAGLDGFTIRE
KTDQGWVRRLEACQSPVWDTALAMTALLDAGVSPGDETLVRAAEWMLGEEIRVPGDWAVR
RPSLQPGGFAFEFANDGYPDTDDTAEVVLALRRMGKPDHLRIREAVDRSVAWLEGMQSSD
GGWGAFDADNTQVLTTRLPFCDFGAVIDPPSADVTAHVVEMLAAEGKSGSRECRRGVRWL
LDNQEEDGSWFGRWGANYVYGTGAVVPALVAAGIPAADRRIRHAVKWLAEHQNEDGGWGE
DLRSYDDRAWAGRGDSTPSQTAWALLALLAAGERESEAVARGVEWLCERQRPDGGWDEDK
HTGTGFPGDFYLSYHLYRVVFPLSALGRYLRGGS
>A0A7V7D1R3|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
IWDTCLSLSALREAGIPADHEAVKDAVDWLFKKLITSRGDWAYRAHDLEPAGWAFQFENT
YYPDVDDTPMVLMALQRAHAIDRVGYKNKMEKAVNWLVGMQSSDGGWGSFDIDNNYLYLN
KIPFADHGALLDPSTSDLTGRCVELLSMLGYGLEFPPVSRAVEFLRKEQEECGAWFGRWG
VNYVYGTWSVLKGLKQAGEDMSKPYIRKAVEWLKSCQNPDNGWGESCNSYAGVSCAGKGK
STVSQTAWALLGLMAAGEVKSSAVQRGVHYLLNAQDRQGSWEEKLYTGTGFPMVFYLRYH
GYRQYFSLWALGEYRRLRTGNKTSQDKAALNEPASFRLTALKKKR
>A0A852VDL9|squalene-hopene cyclase|EC 5.4.99.17|Edaphobacter lichenicola|TrEMBL
MGISASNPKGVDHPAQPRFGRMDVGLDRITQGVARAKDWLFAQQHPDGYWCGELEADSML
ESDYIFMHTLLGTGEPGRMERAINEILRHQNDDGGWGLFPGGPSNISYGVKAYLALKLMG
WSKDHPVLVKAREWVLAHGGVVECNTFTKIYLCALGQYDYDAVPAIPPEIVLFPNWCYFN
IYEISSWSRGILVPLSIIYAKKPFKKLAPEQGIEELFVGGRENANLHLRWDKKKPFGWRN
FFLAVDRVMHLAERVHIRPLRKVALKRAEAWMLERFEKSDGLGAIYPAMLNSIVALRCLG
RSVDDPQLIRALDEFEKLGIDCPDGTDDYSTPTFRMQPCFPPVWDTAQAMYALGEAGVRR
DDSRMLKAADWILSKEVRQKGDWAEKVKNVEPGGWYFEFNNEFYPDVDDTGQVLLALNCV
DNPRERYQYDACQRALNWIWAMQCKNGGWASFDRDNTKMIFQYIPFADHNAMLDPPTVDI
TGRMLEMLALYGVNRSDPRVEKAIQFILKEQESDGSWFGRWGVNYLYGTFLVLRGLEAMG
FWNHEPAVQQAAEWIRMVQNADGGWGETCGTYDDPNQRGIGPSTPSQTAWAVLGLLAAGD
TRSDSVAKGIRWLVDRQHEDGSWDELVPGRNGESYYTGTGFPRVFYLGYHLYKQYFPLLA
LTTYERAMQSGTAH
>T2AZQ2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANLVPDKIIIEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRVQEVNGSWFGRWG
>T2AZF2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAVHALLEANLALDKAIMQKAADWLVERQILDVIGDWGANARGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRVDPNRYSEAIERGAEWIIGMQSGNGGWGAFDKDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMLAQLGYGYEIEAVSR
>T2AY71|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAIVSIALRESGISEDDPRIRESCDWLIDREIRFRGDWYHKNPVEVEPSGWVFEF
NNKWNPDVDDTAMVLMALRQTPTDNQQRRDESFKRGMEWMKAFQCRDGGWAAFDKDCTKS
ILEKVPFADHNAMLDPECADITARILELLGYEGYPVDDPQVKRGLAYLRSQQETDGSWYG
SWG
>T2AZ79|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAICSNALLDSGSPTDHPALVRAGKWIVSKQVTKRGDWQVKNPKAEPDGWAFEFY
NELYPDTDDTAEILLFLNRVEIPDNRWKLSECQRAMDWLLSMQSRSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGKWGFNKQHPQVKRAIKFVKERQEIDGCW
>T2B0A2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLNGLSLLESGLTLKDNAIQKACKWLEKKQILKIKGDWIANNKNLLPGGWAFQY
KNDFYPDVDDTAVVAMFLDRAGYQNKKIIEKACNWIVGMQSKNGGWGAFDKNNTFYYLNN
IPFADHGALLDPPTADVSARCVSMLSQIDKKNYKNVIQKGVRFLKNEQEKDGSWYGRWG
>T2AZ57|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPGLSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSW
>T2AXI8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPGLSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSKPIQRAANWVAGMQSRGGGFGSFDVNNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNNIKSEQEEDGSWYGRW
G
>T2AZD7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLRDEPGDWRIQKPGLSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTKNKSYSEPIQRAANWIAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGRW
G
>T2AZI0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAICSNALLDSGLPTDHPALVRAGKWIVSKQVTKRGDWQVKNPKAEPGGWAFECY
NELYPDTDDTAEILLFLNRVEIPDNRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFAVHKALLDPPTVDVSSRILWMLGKWGFNKQHPQVKRAIKFVKERQEIDGCWFGK
WG
>T2AZW7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PMWDTGLAALALQEANPKATRHSREKAYNWLKTKQLDKQPGDWQIQQPHLNGGGWAFQFE
NPHYPDVDDTAVVAFAMANACDLNNLEESIHRATHWTAGMQSKNGGFGAFDCDNTDYYLN
HIPFADHGALLDPPTADVSARCAMLLGHQLNSHPEYQKTLDKTITFLRKEQESDGSWYGR
WG
>T2B0K4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGLSGISLLESGLTLKDIAIQKACTWLEKKQILGMKGDWFANNKNLLPGGWTFQY
ENDFYPDVDDTAVVAMFLDRAGYQNKKRLERACNWIVGMQSKNGGWGSFDKDNTCHYLNN
IPFADHGALLDPPTADVSARCVSMLSQINKKNYKNVIQKGVEFLKNEQEEDGSWFG
>T2B073|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
WDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQYWND
YYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGDGGWGAFDVDNEHHFLQHIP
FADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGSWG
>I4I3T5|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa PCC 9808|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
KRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVDDPIVARGLKALDNFAIQ
RDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPSIIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKAVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVKMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYQALI
>T2AYQ1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHALLEANLALDKAIMQKAADWLVERQILDVIGDWGANARGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRVDPNRYSEAIERGAEWIIGMQSGNGGWGAFDKDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMLAQLGYGYEIEAVSRVVGYLKREQEHDGSWYGSWG
>T2AY94|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAIVSIALRESGISEDDPRIRESCDWLIDREIRFRGDWYHKNPVEVEPSGWVFEF
NNKWNPDVDDTAMVLMALRQTPTDNQQRRDESFKRGMEWMKAFQCRDGGWAAFDKDCTKS
ILEKVPFADHDAMLDPECADITARILELLGYEGYPVDDPQVKRGLAYLRSQQETDGSWYG
>T2B050|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTALNGYSLLENGSTLKDNVIEKACKWLKKRQILNVKGDWIVNNKNILPGGWAFQY
KNNFYPDVDDTAIVVMFLDRAGYQNENMISRACKWIAGMQSKNGGWGSFDKDNTYHYLNN
IPFADHGALLDPPTSDVTARCISMLSQIDKKKYKNEIMNGVDFLKKEQEKNGSWFGSWG
>T2AZQ7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTCIAQLALLESGIDPEDPMVQSSARWLMDKQIYATADWQVRAKGTRPGGWSFEFD
NLIYPDVDDASIVVMALDQVRLPEAEESRRTDSIQRGVEWMAGMQSKNGGWAAFDKDNNK
KYLTKIPFSDLGRRWTRQVWTSPP
>T2AZH7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPGLSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTKNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVSYIKSEQEEDGSWYGSW
G
>T2AZE8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTAICSNALLDSGLPTDHPALVRAGKWIVSKQVTKRGDWKVKNPKAEPGGWAFEFY
NELYPDTDDTAEILLFLNRVEILDNRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGKWGFNKQHPQVKRAIKFVKERQEVDGCWFGR
WG
>T2AZF7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAICSNALLDSGLPTDHPALVRAGKWIVSKQVTKRGDWQVKNPKAEPGGWAFEFY
NELYPDTDDTAEILLFLNRVEIPDNRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSTRILWMLGKWGFNKQHPQVKRAIKFVKERQEIDGCWFGR
WG
>T2IF96|squalene-hopene cyclase|EC 5.4.99.17|Crocosphaera watsonii WH 8502|TrEMBL
MQTQDRLTQKQPLSLKDAITASQNYLLSLQYPQGYWWAELESNITLTAETVLLHKIWGTD
KTRPLHKVEAYLRQQQREHGGWELFYGDGGEISTSVEAYMALRLLGVPQDDPALIRAKDF
IISKGGISKTRIFTKFHLALIGCYDWKGIPSIPPWIMLFPDSFPFTIYEMASWARESTVP
LIIVFNDKPVFSVDPVFNLDELYAEGVENVKYELPKNNNWGDIFLGIDQVFKFAEQVDLV
PFRKEGLKAAEKWILNHQQETGDWGGIMPPMLNSLLAFRTLNYDVNDPSVKLGFEAIDRF
SIEEDDTYRLQACVSPIWDTAWCVRALTDSGLEKDHFSLVKAGKWLLDKQVMEYGDWAVK
NKAGKPGGWAFEFTNRFYPDLDDSATVVMALNGIKLPDEARKQAAINRCLQWIETMQCKE
GGWAAFDLNNDQAWLNEVPYGDLKAMIDPNTADVTARVVEMLGSCDLEIESDRLNKSLNY
LYKEQEKDGSWFGRWGVNYIYGTSGVLSALAVINPEKHKTQMEQGINWLLSCQNKDGGWG
ETCRSYNDPSLKGKGVSTPSQTAWSLIGLLDAGEALNKFETDAIEGGVNYLLDTQTEEGT
WEESEFTGTGFPCHFYIRYHFYRHYFPLIALGRYQNLSSEFGVRS
>A0A7Y5DTA3|squalene-hopene cyclase|EC 5.4.99.17|Methyloglobulus sp|TrEMBL
MFTDANSTTHSQDAQSTSTAIVFKDGQLDLAIQKAQEKLLSLQDKRGYWVFDLEADCTIP
AEYIMMMHYLGEIDGPLQAKIANYLRSRQSGDGSYPLFTHGSGDISCSVKVYYALKMAGD
SIDAPHMASLRTWILNYGGAAKANVFTRIALAIFGQLPWRGVPFIPPEIMLFPKWFPFHL
DKVSYWSRTVMVPLFILCTLKATAKNPNKIDVLELFVTHPDEEQHYFPERTFLNKIFLAL
DKFGRIAEPYIPATIHQRAIDNARDWVIERLNGEDGLGCIFPAMVNAYESLLLLGYPKDH
EYVVTARKAIDKLLVITDDMAFCQPCVSPVWDTALAALALQESDKSNNAKNLTRAYDWLK
SVQLSDEPGDWRVSKPDLAGGGWAFQYANPHYPDVDDTAVVGFAMADSNLPDLDESIHRA
TRWIEGMQSRNGGYGAFDVDNTYYYLNEIPFADHGALLDPPTADVSARCAMLMAKAGKGQ
GLYQAALERSINYLRKEQEADGSWFGRWGSNYIYGTWSVLLGLEQTNVAKTDSMYRNAVK
YLKGVQREDGGWGEDNLSYHDVSYSGKYHFSTAFQTAWAVLGLMAAGEARSSEVKKGIDF
ILRTQQADGVWNDNCFTAPGFPRVFYLKYHGYDKFFPLWALARYRNELK
>A0A1E3FJS2|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia contaminans|TrEMBL
MNDLTEMATLSAGAVPAGVDTAVARATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AVDGLFPNYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKSIEKLLVVHDDEAYCQPCLSPVWDTSLAAHALLETRDPRAEDAAIRGLEWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAVAMERAQQLKQNDAYRDSIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGIDYLI
AEQNEEGLWDEARFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNTTRVTVGL
>T2AYJ2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIIIEKAANWLVERQILDVIGDWAANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARSIVYLKRGQEVNGSWYGRWG
>R9W206|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAQVLSPVCDLGLPRNDPRMVKAADWLLSKEVREKGDWSHTVTNTHPSGWCFFFN
NEHQPDVDDTAEVLLALNSVENPRERNQDDASQRALEWIFAMQCKNGGWASFDKDNTKRI
FESIPFADHNAMIDPPTVDITGRILEMLAQYGYTRRDPRVEKAVQFSLQEQEPDGSWFGR
WGVNYLYGTFLVLRGLEAMEYWNHEPAVQQAAEWIRMVQNSDGGWGE
>A0A0F6RMS2|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa NIES-2549|TrEMBL
MVPRGCRTEKMQIQEKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELESNVTITSEAI
LLHKIWKTDKNRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPLND
PALEKAREFILAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMS
SWARGSTVPLLIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWSDVFLWLDGLFKW
AEKTNLVPFRQESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVYDPIVARG
LKAVDNFAIQTDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAIIKAGQWLIDQQILD
YGDWAIKNKIGTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKGVMKRAVNWM
ATMQCKAGGWGAFDIDNDQNWLNSLPYSDLKAMIDPNTADVTARVLEMLGTCDVKMEENR
VKKALDYLEKEQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSSCQ
NVDGGWGETCFSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLV
TQKENGTWDEDYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>C4I4L0|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia pseudomallei MSHR346|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGAVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A7C3L4H8|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
ASSVVNGLSIVTTQKDLPEAIQKSQGYVLMGQAPEGFWVDELEADTSLTSEYLTLRHFLG
MVDPVKQKKAVRYLIDSQLPDGGWNIFYEGPSNISSSIKAYFALKLSGLSSHESFMRRAR
QNILEQGGVVNANVFTKIGLALFGQYDWRGIPLMPSELILLPRWFYFNLYEVSYWSRAVL
VPLLIIYDKKPLCVISKDAGIDELYAVPKEQLSYRFQKDPQWLTWKNFFITVDEILKRYE
RHHLVSLRKRALKKAEEWLMDHIRGEGGLGAIYPAMANSVIALRCLGYPEDHPLVLKGIR
EIEALEVKDEDSLYLQPCHSPIWDTGLTLNVLLDGGFPRNHPALVNAAHWLMSKQTYREG
DWKVKVPHAEPGGWYFQFENEFYPDNDDTAAVLLALAKVSLPDEKAKRNAIMRGLQWLLA
MQCKDGGWGAFDVDNDKVIFNQIPFADHGALLDPSTCDLAGRVLEALGVLGYDKSFPPAA
AAIQFIRRHQEPEGCWYGRWGVNYIYGTWSVLAGLYSIGEDMGQEYVQKAVEWLKLRQNP
NGGWGESCSSYKDYR
>A0A533X871|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
MRSGNPRRFGTCRPPSEISASVKAYFALKLSGVPADESFMIQARDAILAKGGVVAANVFT
KIALALFDQYDWRGIPSMPPEIMLLPKRFVFSLYAVSYWSRTVLIPLLIVFAHRPICRLP
AEQGIEELYVEPRARVRYREVPPFKKDAAWWTWRNLFITLDSILKLYDRLPLQALRKAAV
TKAADWMLNHLKGSGGLGGIYPAMANSIVALRCLGYSVDHPLVVKALREIEELEVNEVVN
DGRGQVETLHLQPCFSPVWDTSLLINALIEVGLPQDHPALLKAGQWLISCQTTKEGDWKV
SAPQAEPGGWYFQFENEMYPDIDDTAEVLMALAKLRLASRDAQQHSIARGYQWVMAMQGS
DGGWGAYDKDNNRTVFNLIPFADHRALLDPSTADLAGRCLELLGTLGYDRTHPAVGPALQ
FLRQEQEADGSWYGRWGVNYIYGTWSVLAGLRAIGEDMTMPYVRKAVAWLESKQNPDGGW
GESCVSYADPTMAGMGDSTPSQTAWALIGLLSAGVTDSISVVRGVNYLLRHQRHDGSWFE
NRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNFRTRGQARADELRLNARETGRFRFPS
>A0A533YML6|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
PVCRIPKEQGIDELYCTARELVDFRREPPFRKDRRWFTWHNFFITLDGVLRFYERVVPQG
LRKKALARAAQWMLERMEGDGGLGAIYPAMANSVVALRCLGYAVDHPLLRKALHEIEALE
VHEGAALHLQPCFSPVWDTPLAINALIESGLPQDHPALVKAARWTLSRQCRKVGDWIMSS
PKAEPGGWYFQFENEFYPDNDDTAVVVMALSKLKMPEWGAQREGVRRGMRWTLAMQGSDG
GWGAYDKDNNKMFLNQIPFADHRALLDPSTADLTGRELEMLGTLGFDMKHPAAVRALRFL
RKNQEADGSWYGRWGVNYIYGTWSVLAGLKAIGEDMQAEYVRRAVAWLVSKQNPDGGWGE
SCLSYAEADAHGVGESTPSQTAWALIALLCAGEVDSLSLLRGVNYLLRQQHAQGVWPERK
HTGTGFPRVFYLRYHGYCQYFPLWALSMYRSLKARGRTRADELREQNRQHGRFRFEA
>A0A7Y6W5T0|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium septentrionale|TrEMBL
MLSRDHSVAVDPVALENSISKATEALLGYRQSDGHWVFELEADSTIPAEYVLLRHYLAEP
VDAGLEAKIANYLRRTQGAHGGWPLVHDGPFDMSASVKSYFALKMIGDSVDAPHMMRARE
AIRSRGGASGSNVFTRFLLALYGVVTWRATPVLPIEIMLLPMWSPFHINKISYWARTTMV
PLMVLAALKPRAKNPKGVGIDELFLEDPKSLRMAPKAPHQSAGWFYLFRSLDAVLRAIEP
MFPKRLRQRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYEALGKDENFPPRAITRRG
IDKLLVIGDEEAYCQPCVSPVWDTALACHALQEAGGEDTLAKAKQGLDWLKPRQVLELKG
DWAVKAPDVRPGGWAFQYNNDHYPDLDDTAVVAMAMDRVRRHSGTREYDEAIARGREWIE
GLQSRDGGWAAFDANNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLGQLGETSESSKA
MADGIAYLRRTQLPEGSWYGRWGLNYVYGTWSVLSALNVAGIDRNDPMVRNAVDWLASVQ
NQDGGWGEDAVSYRLDYKGYEVAPSTSSQTAWALLGLMAAGEVENPAVARGVEYLKATQS
EKGLWDEQRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNSRVVGVGM
>A0A150L8D0|squalene-hopene cyclase|EC 5.4.99.17|Heyndrickxia sporothermodurans|TrEMBL
MRKDVIRQRDKIIERLLSDQSRNGSWEYPFETGILTDCYMIILLRVLEKNDESLIQSLVN
RILKEQYNDGTLKLYVDEGKGNLSLTITAYYALLFSGYVEKSSPNLIRAKEFIMINGGLH
KANMFTLALLSLTGQIEWDSPFPIPVEAVLLPEKFPINFFDISVFGRANLAPLLIVADYK
LVVKPANSPNLADLIIRKTDGKNKFTDETRSIFDFIEQGIEQIVELKEDVHEKALEYLEQ
YLYDHIELDGTLYSYFSATFYMIFAFIARGKDKNDSKIIKAIDGLKSMICTINGDKHCQY
TTAHVWNTALISSALQFAGIPHTEVNIRQANQYLLERQHVKLGDWTVHNPHTYPGGWGFS
NVNTINPDIDDTIASLRALHQLIIEQPHYYNVWDRGIRWVLSMQNDDGGWAAFEKMLIIH
Y
>A0A832AKM7|squalene-hopene cyclase|EC 5.4.99.17|Acidimicrobiales bacterium|TrEMBL
SIIALELRGYALDHPVLARAISGWEGFTIRRDGMRMLEACQSPVWDTALATIALSDAGVA
ADDEHLVRAATWLLGEEVTVRGDWSVRRPEVPTGGWSFEFENDSYPDVDDTAEVVMALRR
VAHPDHAALEAAAARGIAWLEGMVSADGAWGAFDADNRRQLLYEIPFSDFGAVIDPPSAD
VTAHALEMLADERRADPQRMERAIAWLRNEQEPDGAWYGRWGVNYVYGTGAVVPALVAAG
LRPDDPAIVRAVEFLELHQNDDGGWGEDIRSYDDPTLRGEGVSTASQTAWALLALVSAGR
AGSQAARRGVGFLTRTQRADGNWDEPWYTGTGFPGDFYINYHLYRLCFPVTALGRWLRAV
RPGGAAPETASASRIQPDAVDRRRGASGDARRPSQGQRFGSASVDDLALRSRSSARSRTL
RRRRAPRSTGPEDGT
>B9BP78|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia multivorans CGD2|TrEMBL
MNKSALSPWSALDTAIARGRDALARLQQPDGSWCFELESDATITAEYILMMHFMDRIDDA
LQERMARYLRAIQRLDTHGAWDLYVDGAPDVSCSVRAYFALKAAGDSEHAPHMVRARDAI
LKLGGAARSNVFTRILLATFGQVPWRATPFMPIEFVLFPKWVPISMYKVAYWARTTMVPL
LVLCSLKARARNPRNVSIPELFVTPPDQERHYFPPARGMRRAFLILDRVVRHVEPLLPKR
LRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMDVLGYPEDHPLRRDCENALAKLL
VTRPDGSVYCQPCLSPVWDTAWSTMALEQARSVAVPESDESARALDELDARIARAYDWLA
TRQVNDLRGDWIENAPADTQPGGWAFQYANPYYPDIDDSAVVTAMLDRRGHTHRNADGSH
PYAARVARALDWMRALQSRNGGFAAFDADCDRLYLNAIPFADHGALLDPPTEDVSGRVLL
CFGVTRRAEDRASLARAIDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALAGEDPSQP
YIARALEWLRAHQHADGGWGETNDSYLDPALAGTNGGESTSNCTAWALLAQMAFGDCASD
SVKRGIAYLQSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLAGAAE
ARARSSSGRAPHAAGAALA
>A0A538A5D6|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MQPASTAQLNSNSIDQATAATLPEGALEASVERARDHLMSLQDPGGWWKAELETNVTMDA
EDLLLREFLGIRDADALERAANWIRSQQRDDGTWANFYGAPANLSTTIEAYAALKLAGDP
PDAPHMTAAREYILGAGGVENARVFTHIWLALFGLWPWEEVPALPPELIYLPPWFPLNIY
DFACWARQTIAALTIVRAERPVRPIGIDLDEIFTGRPVKPTPRTFRGRVLLWLDAVARLY
ERRPLKLLRRRATARVERWVLDRQEADGSWGGIQPPWVYSLMALSVVGHTVDDPAMRKGL
EGIEGFLINEGSIRRLEACQSPVWDTALAIIALTDAGVAADDPAVVKAADWMLAEEIRIK
GDWAVRRPDLEPGGWAFEFDNDNYPDIDDTAEVVIALRRVDHPEPDRVSDAIRRGVVWTL
GMQSRNGGWGAFDADNVRELCRDIPFCDFGEVIDDPSADVSAHVLEMLGGEGLAGLPAAR
RGISYLLDEQESRGSWFGRWGINHVYGTGAALPGLVECGVPPTDSRLRRAAAWLEEIQNP
DGGWGEDGRSYDDPAWIGRGPSTASQTAWALIALHALGERTPAVELGLAWLVEHQREDGT
WDEPEYTGTGFPGHFFINYHLYRLSFPLMALGRWAAAGER
>A0A7S9CWJ8|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium genosp. L|TrEMBL
MLSSDHSVAADPVAPVDPVALQTSISRATEALLGYRQADGHWVFELEADSTIPAEYVLLR
HYLAEPVDAALEAKIATYLRRVQGAHGGWPLVHDGPFDMSASVKSYFALKMIGDSVGAPH
MVKAREAIRARGGASGSNVFTRFLLALYGVVTWRATPVLPIEIMLLPMWSPFHINKISYW
ARTTMVPLMVLAALKPQAKNPKGVGIDELFLEDPKTIRMAPKAPHQSASWFYLFRSLDAV
LRVIEPMFPKRLRQRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYEALGKDENYPPR
ATTRRGLDKLLVIGEHEAYCQPCVSPVWDTALTCHALEEVGGDSFARAKEGLDWLKPRQV
LELKGDWAVKAPDVRPGGWAFQYNNDHYPDLDDTAVVVMAMDRARRQTGTKEYDAAIARG
VEWIEGLQSRDGGWAAFDANNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLGQLGETA
DSSKAMADGIAYLRRTQLAEGSWYGRWGLNYVYGTWSVLSALNVSGIGRNDPMIRRAADW
LLSIQNQDGGWGEDAVSYRLDYKGYETAPSTSSQTAWALLGLMAAGEVENPAVARGVEYL
KATQTEKGLWDEQRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNSRVVGVGM
>A0A538GM66|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MAVTIPELTQLDTAIERGTRRLLELQRPDGVWVGELESNVTMTAQHLFWHHYLDLRTPEL
DRGIANDLLARMRDDGTWSIWFEGPADLSTTIEAYVACRLAGVDPGPRTLAYIRREGGIP
KSRLFTKCFMALLGQWPWQRMAPIPPELVLVPPGSPFSIYDFSCWARQTFVALSVAQSLR
PVRPADVDLTAIGARPGKTRPPGRPNRLRRRAVTVAERWIRERQEADGSWGGIQPPWVWG
IIALAALGNGLDDPALGKAVEGWQGFMVSDGERLRPEACQSPVWDTALAALALRACGVPA
DHEALRRAGDYLLREEVTVKGDWAIRRPDLAPGGWAFEFENDLYPDVDDTAVVALALREL
GRGEDAIARGVDWLVGMQSRDGGWGAFDVDNDTMWLYKIPFCDFGKVTDEPCADVTAHSL
ETLGTLGSHPDAAGRGLDWLLSEQEKDGSWYGRWGVNYLYGTGAALPGLEACGVPHDHPS
MRRAVAWLDSVQQENGGFGEDIRSYADPAWRGRAEFTTPSQTAWALLAYVAAGNAEDSSC
GRAADYLCAAQRTDGDWDEEHFTGTGFPLDFMIRYHLYRITFPLLALGRLRERLAG
>A0A6B2Z2S1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID14515|TrEMBL
MTATTDGSAGAAKLSGAPADDPTDTTTAADDVTAAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDAETTRAAALFIRGEQLGDGTWNTFYGGPGDLSATIEAY
VALRLAGDRPDEPHMARASGWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPDHPNPARKLAPPTSW
DGLFQRLDKGLHLYHKVAPRPLRRVAMNLAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVMKAGLASLDRFAVRREDGARMVEACQSPVWDTCLATIALADAGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARMQAAIDRGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLANHPRTREGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALIAAGLPAGHP
AIRRAVGWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDTRSV
ARGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRA
DAAEGA
>A0A844SV11|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium pachyrhizi|TrEMBL
MLARDHSVAVDPVALEKSISKATEALLGYRQSDGHWVFELEADSTIPAEYILLRHYLAEP
IDAGLEAKLGNYLRRVQGAHGGWPLVHDGPFDMSASVKSYFALKMIGDSVDAPHMVRARE
AIRSRGGASGSNVFTRFLLALYGVVTWRATPVLPIEIMLLPMWSPFHINKISYWARTTMV
PLMVLAALKPRAKNPKGVGIDELFLEDPKSVRMAPKAPHQSASWFYLFRSLDAVLRVIEP
MFPKSLRQRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYEALGKDENFPPRAITRRG
IDKLLVISELEAYCQPCVSPVWDTALACHALQEAGGDATLAKARQGLDWLKPRQVLELKG
DWAVKAPNVRPGGWAFQYNNDHYPDLDDTAVVVMAMDRVRRHTGTREYDEAIARGREWIE
GLQSRDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLGQLGETVESSKT
MADGVAYLRRTQLAEGSWYGRWGLNYIYGTWSVLSALNVAGVDRDDPMIRKAVGWLASVQ
NQDGGWGEDAVSYRLDYKGYEVAPSTSSQTAWALLGLMAAGEVENPAVARGVEYLKATQT
EKGLWDEQRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNSRVVGVGM
>A0A2U3KXV7|squalene-hopene cyclase|EC 5.4.99.17|Syntrophobacter sp. SbD1|TrEMBL
MQFKLLAKRCETELIGCCQKKINAIRWGQRIAEIICFWGKGMKLFKIGAAITRTAERTEE
RAEAVREPLAXWIPQIEEAIRKSSEYFYRFQHPEGYWWAELESNVTITCEYVMLAFLLGF
SISGKKKSIVKYLLKHQNENGGWGLYYGDKGELSTTIEAYFALKLLGEDPASEPLTKARA
FILQRGGIEAARVFTKIWLALFDQYDWNKVPSMPVELVLLPPEFYFNVYEFSSWARGTAV
PLSIVLCIRPKFGLADSLRIHELYAPVQGNKLDSRINKLFFVFDRIAKILEKRPIRKLRS
KATGAAAKWIIDHQEESGDWGGIQPPMVYSLLALHYLGFPLSHDVMKKGLKAIDDFCIED
EEGLRMQSCISPVWDTALTALALLEAGVSPKHPAMDKSAKWLISQQILTGGDWQFKNSCR
PGGWAFEFSNSRYPDVDDSAVVLNVLNRFSPHRCDGLESCVSRGMEWVISMQSSNGGWAA
FDRDNGMEILNRIPFADTEAMVDPPSADVTGRVLEVMGCCGYDRSHPAARRGLAFLERIR
EKDGSWWGRWGVNYIYGTWSVLRGLVSIGEDLKSPAVRAAMHWLKDHQNPDGGWGEDCDS
YKWPELSGQGPSTASQTAWAIMGLLAGGEEKSPEVSKGIQYLVRTQKPDGTWDEIHFTGT
GFPKHFYIKYHNYRNCFPLMALGQYLKRLR
>A0A564WBJ0|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Defluviicoccus seviourii|TrEMBL
MRWSAAAVAQVEVEAARTESVLDRTIDDGLAWMFDRQASDGHWVFELEADASMPADYIML
SHYLGDIDEPLERKIATYLRRRQGAHGGWSMYYGGEFDLSLSVRAYFALKIMGDDPEALH
MRRAREAILAQGGAAKVNVFTRYALALFEQIPWRGVPWMPAETMLLPKWAPFHLDKVSYW
SRTVMVPLLVVSAFKPRARNLRKVNIRELFTTPPERHRGYQTNPTGSRIGNGLLVLDAVA
RLAEPFVPRPLQKIAIDRAMRFIEERLNGDEGLGGIYPAMMYALIAMDALGYPHDHPSRL
MTRTAINKLLVVHADEAYCQPCVSPVWDTALMLHAFLEAGVPGDDDAVASACEWLCARQI
LDVEGDWAVNRAGVRPGGWAFQYRNDHYPDVDDTAVVAMALNRADPDRYRHAVDRAAEWI
IGMQSANGGWGAFDADNQHEFLNNIPFADHGALLDPPTADVTARCIGLLAQLGYPATHPA
IARALTFLQREQEADGSWFGRWGTNYIYGTWSVLAALNAVGEDMTAPYIQRAVAWLKARQ
RDDGGWGEDCATYWPNQRDGAKASTPSQTAWALLGLMAAGEVDSDSVERGIGHLMAAPRE
GGKWDETYYNAVGFPRVFFLSYHGYSAYFPLWALARFRALKGGNSRRPAYGL
>A0A7Y5D3H6|squalene-hopene cyclase|EC 5.4.99.17|Methylococcaceae bacterium|TrEMBL
MFTDANNQNHDQTPQSSATPISSRLSNLDLAIHNAQDALLKLQHENGYWVFELEADCTIP
AEYIMMMHYIGEIDPGLQAKIANYLRARQSADGSYPLFTGGSGDISGSVKVYYALKMAGD
AVDAPHMQRLKNYILSQGGAAKANVFTRIALAMFQQLPWRGVPYIPAEIMLLPKWFPFHL
DKVSYWSRTVMVPLFILCTLKATAKNPHKIDILELFVTHPDLEQHYFPKRTLLNKFFLGL
DNLGRATNAIVPKRMRSLAINKAKDWFVARLNGEDGLGGIFPAMVNAYEALLLLGYPHDH
PQVVTARKAIDKLLVINEHDAYCQPCLSPVWDTALAALAIQEVDKHSNAPALTRAYDWLK
SKQLRDQPGDWQVARPNLAGGGWAFQFENPYYPDVDDTAVVAFAMADSQLPDLDESIHLA
TRWIVGMQSTNGGFGAFDVDNTNYYLNEIPFADHGALLDPPTVDVSARCAMLMAKVTKDH
AEYLPALERTIDYIRNDQEADGSWFGRWGTNYIYGTWSTLIGIEQTNLPKSDPMYTKAVH
WLKSIQREDGGWGEDNFSYHDTACAGHYRFSTAFQTAWALLGLMAAGEASSKEVKAGIDF
LLRGQQNDGVWNDKCFTAPGFPKVFYLKYHGYDKFFPLWALARYRNELKKQ
>A0A522JSJ2|squalene-hopene cyclase|EC 5.4.99.17|Pandoraea sp|TrEMBL
MQTAHDQSAPDMTRQSLPGEFAQRVETGVERARDALLALQHADGYWLFELEADATIPAEY
VLLRHYLGEAPDAALEAKIAVYLRRIQGNHGGWPLFHDGAFDMSASVKAYFALKMIGDPV
DAPHMVRAREAILARGGAAGSNVFTRILLGLYGVVDWRAVPMMPVEIMLLPTWFPFHLSK
ISYWARTVIVPLLVLQAKRPRARNPKGVTIDELFIGSPREVGPPSRAAHQSRLWFTFFAG
VDALLRATDKWFPKRLRQRAIDAAVRFVDERLNGEDGLGAIFPAMANAVMMYDVLGYAEN
HPRRAIARRSLDKLLVVHEQEAYCQPCLSPIWDTALSAQALLETGDARAIEQAERGLSWL
APLQILETRGDWISRRPHVRPGGWAFQFANPHYPDVDDTAVVAMAMDRVARLRGDDRFRE
AIDRGCEWVIGMQSGNGGWGAFEPENTHLYLNNIPFSDHGALLDPPTADVSARCLSMLAQ
LPLSPEREVAAARARQYLLDEQEADGSWYGRWGMNYIYGTWSALCGLRAAGLAPGSAPLQ
RGAQWLLAIQNDDGGWGEDGESYKLDYHGYERAPSTASQTAWALLGLMAAGYVDDPAVAS
GIAYLLETQGGDGLWEEALFTATGFPRVFYLRYHGYRKFFPLWALARYRNLAVRNLCPVP
GGM
>A0A6G2W0H1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID161|TrEMBL
MTATTDGSTGATLPPRAAAASDTTLTTPETAGVPEAAARAARRATDFLLAAQDNQGWWKG
DLETNVTMDAEDLLLRQFLGILDEHTAQAAAKFIRGEQREDGTWATFYGGPGDLSATVEA
YVALRLAGDVPDAPHMARAAAWIRERGGIAAARVFTRIWLALFGWWKWEDLPELPPELLY
FPTWFPLNIYNFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAQPNPPQPLAPVAS
WDGLFQRLDKVVRGYRKVAVRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVLREGLASLDRFAVWREDGARMIEACQSPVWDTCLAAIALVDAGLPVDHPQ
LVKAADWMLGEEIVRPGDWAVRRPHLPPGGWAFEFHNDNYPDIDDTAEVALALRRIRHHD
PERVDRSIGRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAAEGLAHDPRTRRGIDWLLAEQEADGSWFGRWGVNYLYGTGSVVPALTAAGLPGSH
PAIRRAVAWLERVQNDDGGWGEDLRSYKYAKEWSGRGASTASQTAWALMALLAAGEKGSR
AVERGVQWLAETQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFER
KLLAPAGPAPTRPEGD
>A0A6I6KSN1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces rimosus R6-500|TrEMBL
MTATTDGSTGALPPRAPSAGDATAETTENDPAAPTSTAAAARRATARATDYLLSVQDAAG
WWKGDLETNVTMDAEDLLLRQFLGIGDPRTTEAAARHIRGEQRDDGTWATFYGGPGELSA
TIEAYVALRLAGDEPDAAHMARAAAWIREHGGVAAARVFTRIWLALFGWWKWEDLPELPP
ELIWFPKWFPLNIYDFACWARQTIVALTIVCSVRPVRPAPFALDELHADPARPNPPRPLA
PPTTWDGVFQRLDKGLHLYRKVAVRKLRRSALRAAASWIVERQENDGCWGGIQPPAVYSI
MALHLLGYDLGHPVLRQGLESLDRFAVWREDADGAPVRMIEACQSPVWDTCLAAIALADA
GLPADHPQLVKAADWMLAEQIRRPGDWSVRRPRLPSGGWAFEFENDNYPDIDDTAEVVLA
LRRIQHPDPERVDAAVQRAVRWNLGMQSKNGAWGAFDADNTSPFPNRLPFCDFGEVIDPP
SADVTAHVVEMAADLGMTHDARVRRGIRWLLAEQEPDGSWFGRWGTNYIYGTGSVLPALA
AAGIPASHPAVRRAVRWLERVQNEDGGWGEDQRSYHDKAWAGRGESTASQTAWALMALLA
AGERESAAVARGVRWLAGTQRDDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYV
NGGPAGASQGA
>A0A7K3EHZ1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5476|TrEMBL
MTATTDGSTGALPPRAPSASDTDHGTPVAAGVQEAAVHAVRRATDLLLSRQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDDRTTRAAALHIRGEQRPDGTWATFYGGPSDLSATVEAY
VALRLAGDDPAEPHMARASAWIRERGGIAAARVFTRIWLALFGWWKWDDLPEMPPEILYF
PSWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDSGRPNPPSPLDPLGSW
EGAFQRLDRALHGYHRVAPRRLRRAAMNRAARWIVERQENDGCWGGIQPPAVYSIIALHL
LGYDLRHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQL
VKAADWMLGEEIVRPGDWSVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHHDP
ERVAKAVRRGVRWTLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAAEGLSHDPRTRRGIEWLLAEQEASGAWFGRWGVNYVYGTGSVVPALVTAGLPAAHP
AIRRAVSWLETVQNDDGGWGEDLRSYRDPAEWGGKGASTASQTAWALLALLAAGERQTKA
TERGVEWLARTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPALLK
PGGR
>A0A4P9URZ8|squalene-hopene cyclase|EC 5.4.99.17|Methylotuvimicrobium buryatense|TrEMBL
MLIETIFHPDQDASSTSLSYPRLSLNDAITCAKARLLELQNEEGYWVFELEADCTIPSEY
ILMMHFMGEIDARLQAKIVQYLHEQQDRDGSYPLYKGGPGDLSCTIKAYYAMKLAGDSIQ
AQHMVKARRWILARGGGAKANVFTRIMMAMFEQIPWRGVPFIPVEIMLLPKWFPFHIDKV
SYWSRTVMVPLFILCTYKVKARNPNNVGISELFITQPESEKNYFAHVKTPLGKSILAADR
MGRLMEPLIPGFVRRKATIKARDWFLSRLNGYDGLGAIFTSMVNAYEAMDYLGIPADDER
RRIAREAIDRLLVVKPDKAYCQPCVSPVWDTGLATLVLQEVDRRERDPIAEQSLTKALNW
LAGRQLSNEPGDWRVQRPNLPGGGWAFQFGNSHYPDVDDTAVVALAMIESGDREFAENIE
RAGVWIAGMQSANGGYGAFDADNTHSYLNHIPFADHGALLDPPTADVSGRCVMFLSKLVD
RQPEYRAVIDTCITYLRNQQEADGSWFGRWGTNYIYGTWSVLTGFESAGISKHDSHIRKA
VVWLKSKQRADGGWGEDNDSYHDVGVRGESETGSAFHTALALLALMSAGEAGCPEVKSGI
NYLLKNQQDDGFWKDDGFNAPGFPKFFYLKYHGYDKYFPLWALGRYRNECGDFIS
>C6BRH5|squalene-hopene cyclase|EC 5.4.99.17|Maridesulfovibrio salexigens (strain ATCC 14822 / DSM 2638 / NCIMB 8403 / VKM B-1763)|TrEMBL
MNKKSAMKLKKKAKNHVVSLLQPTDALNRVMKRFRSLQSPEGYWVFALEADVTIPSEYIM
FNRFLGRKMDKGLAERLGNYIRAKQMADGGWPLHDNDGPVNISASVKAYMALKMLGDNKD
AEHMVRARQIILAKGGAETANVFTRICLATFGQIPWHCPPAMPIEIVLLPKWFFFHLDKV
SYWSRSVIYPLLIIYAKQPVCRLRPEEAVPELFCKPAEEHIHIDKYRDKGWRKNLFILLD
RVLKRTIHLVPKSINKKALNYAEKWTREHMAGRGGIGAIFPAMANAVMALSLLGYDESDP
DFARGMQSVDDLMVDKFHVPEKSPWEHTVITGGAELSAAPELDISPDHGTAENLEQAMCQ
PCNSPIWDTCLTLSAMMEAGENQDSKSTQQALNWLWDQQIFFRGDWISKAPKLEGGGWAF
QFENTFYPDLDDTAMVLMAMCRAGVLDQPEHRENFIKGVNWLIGMQSSNGGWAAFDIDNC
AEYLNDIPFADHGALLDPPTSDLTARVIELLGVLGYDKSFRPIKDGIEFLKKEQEDDGSW
FGRWGVNYIYGTWSVLCGLRQAGEDMNSSYVCKAVEWFENHQNKDGGWGESCLSYNDKNY
AGLGDSTASQTAWALLGLMAAGRVHSKAVSRGVRYLLDTQKDDGSWDESLFTGTGFPRVF
YLRYHGYSQYFPMWALGVYQRFSADEDTKQIMMRRKSPLDLGRKW
>A0A838DDZ1|squalene-hopene cyclase|EC 5.4.99.17|Chthoniobacterales bacterium|TrEMBL
MPPSSSNVIPLPSALPREASSYAPETSDISEAIRRAQENLLRQQHPDGHWCGELLVDSTL
CSDYVLFMHWLGEVDERLQERCVAHILKRQLPDGGWNIYFGGPSEINACVKAYFALKLSG
PSPDLPFMQEARANIMRLGGIPRMNTYSKLYLALLGQFPWQYLPSIPVEMILLPEWAPFN
LYRMSSWSRAMLVPLAIINHFKPTRELPEAQQLHELYPVGTEHNNFTLPRDPRFLAWRNF
FLRGDHALKLISKLGWRPMRKRALEEAERWMLTRIGEGSDGLAAVFPAMLNAMIALRALG
YAKDHPAYAKAMSDFRGLFVDDPEDFRIQPCLSPVWDTSINIIALAESGVPAEHPALQKA
AAWLADKEVRVRGDWTVNNPHPEASGWAFEYNNVYYPDTDDTAMVLMGLRLVRPQDAAGV
DELFKRAIAWQLSFQCGDGGWAAFDKEVTQHWLEDMPFADHNAILDPTCSDLTARTLELF
GYVGFDEKQECVRRAVQYLIDTQEDDGSWYGRWGVNYIYGTWQVLRGLRAINEEMSQDWI
LRGRDWLESCQNDDGGWGESCASYETPVLKGKGESTASQTAWALMGICACGDLDRPSVQR
GLRYLLSTQNNDGAWDEPQITGTGFPRVFYLKYDMYRQNFPLLALATYLNYRSGRGHYPS
FYCCSRS
>A0A7K3FF59|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5477|TrEMBL
MTATTDGSTGASLRPLAASASDTATDTDITIPAAAAGVPEAAARATRRATDFLLSQQDAQ
GWWKGDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELS
TTIEAYVALRLAGDSPDAPHMARAAEWIRSRGGIASARVFTRIWLALFGWWKWDDLPELP
PELIYFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPVRPNPPRPL
APAASWDGAFQRIDKALHAYRKVAPRRLRKAAMNSAARWIIERQENDGCWGGIQPPAVYS
VIALYLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVP
EDHPQLVKASDWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRR
VRHHDPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSAD
VTAHVVEMLAVEGLAHDPRTRRGIQWLLDAQEADGSWFGRWGVNYVYGTGSVIPALTAAG
LPTSHPAIRRAVRWLESVQNEDGGWGEDLRSYRYVREWSGRGASTASQTGWALMALLAAG
ERDSKAVERGVEWLAATQREDGSWDEPYFTGTGFPWDFSINYNLYRQVFPLTALGRYVHG
EPFAKKSRAAEDLTESAPAEVKGS
>L8ETX8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces rimosus subsp. rimosus (strain ATCC 10970 / DSM 40260 / JCM 4667 / NRRL 2234)|TrEMBL
MTATTDGSTGALPPRAPSAGDATAETTENDPAAPTSTAAAARRATARATDYLLSVQDAAG
WWKGDLETNVTMDAEDLLLRQFLGIGDPRTTEAAARHIRGEQRDDGTWATFYGGPGELSA
TIEAYVALRLAGDEPDAAHMARAAAWIREHGGVAAARVFTRIWLALFGWWKWEDLPELPP
ELIWFPKWFPLNIYDFACWARQTIVALTIVCSVRPVRPAPFALDELHADPARPNPPRPLA
PPTTWDGVFQRLDKGLHLYRKVAVRKLRRSALRAAASWIVERQENDGCWGGIQPPAVYSI
MALHLLGYDLGHPVLRQGLESLDRFAVWREDADGAPVRMIEACQSPVWDTCLAAIALADA
GLPADHPQLVKAADWMLAEQIRRPGDWSVRRPRLPSGGWAFEFENDNYPDIDDTAEVVLA
LRRIQHPDPERVDAAVQRAVRWNLGMQSKNGAWGAFDADNTSPFPNRLPFCDFGEVIDPP
SADVTAHVVEMAADLGMTHDARVRRGIRWLLAEQEPDGSWFGRWGTNYIYGTGSVLPALA
AAGIPASHPAVRRAVRWLERVQNEDGGWGEDQRSYHDKAWAGRGESTASQTAWALMALLA
AGERESAAVARGVRWLAGTQRDDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYV
NGGPAGASQGA
>A0A3N8B326|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp9143|TrEMBL
MNDLTDMATLSAGTTPAGLDAAVASATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPIAKNPRGVRIDELFIDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AVDGLFPNYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDALGYAEDHPNRAI
ARKSVEKLLVVQEDEAYCQPCLSPVWDTSLAAHALLETGDARAEEAVLRGLDWLLPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLKQTDQYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTSDVSGRCLSMLSQLGESAL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLI
AQQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A5M6IE41|squalene-hopene cyclase|EC 5.4.99.17|Roseospira marina|TrEMBL
MNQALHKTPVIDLDSQTSFSSSGSPPFDRRTSVDTDAANDGGADPAEAAAPPDGAPHGAP
DKSVDATPDGAVDPAAVDRVIDEASDWLRTHQKGDGHWVFELEADATIPSEYILLNHFLD
EINDPLERRIAVYLRRIQAAHGGWPLFHDGDFDMSASVKAYFALKLVGDAPDEPHMVRAR
EAILKRGGAARCNVFTRYTLAMFGQVPWRACPVARVEAALLPRWFPFHMDKVSYWARTVM
MPLFVLYSRRARAENPRGVDIRELFVTPPEKERRYHSNPTGHWIGSAFLRVDAVARLLEP
LFPAAVERRATERVLRFVTERLNGVDGLGAIFPAMANTLMMFHILGYEKSHPQVRMARKA
MDGLVIEKGDHAYVQPCLSPVWDTGLASMALTEVDAQAHGDGATSGSRESAVAGACAWLR
DKQVLDVEGDYAATRPGVRPGGWAFQYNNDFYPDVDDTAVIGMLLDRARLPQNKEAIERA
AEWILGLQSKNGGWGAFDADNEYYILNNIPFADHGALLDPPTVDVSARCIGFLAQIGYDR
DHPAIARGLAYLKKEQEPDGSWFGRWGTNYIYGTWSALAAFNATGEDPQAPHIRAAVAWL
HRRQQADGGWGEGCESYWTDKRDFVKASTPTQTAWAVLALMAAGEVDSPEVRRGIAYLSK
APRTGGLWDEKLYNAVGFPRVFYLKYHGYPAFFPLWAMARYRNLTRGNSGQVSWGL
>A0A6I5EVR5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8356|TrEMBL
MTATTDGPAGAAELSATTAGHPDRTTLVPDEVLAAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPSDLSATIEAY
VALRLAGDAPDAPHMARAASWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFL
PSWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPARPNPSRKLAPAASW
DGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIVERQENDGCWGGIQPPAVYSLIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMVEACQSPVWDTCLATIALVDGGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPGLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARVEAAIERGVRWNLGMQSRNGAWGAFDADNTSSFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGRARHPRTRRGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALIAAGLPAAHP
SVRRAVEWLESVQNDDGGWGEDLRSYREEKWIGHGESTASQTAWALLALLAAGRGDSVAV
TRGVTWLTDAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRT
GAAQDA
>A0A552JDA0|squalene-hopene cyclase|EC 5.4.99.17|Microcystis novacekii Mn_MB_F_20050700_S1D|TrEMBL
MQIQDKISEIAAKTAKASELSQNYLLSTQYSEGYWWAELESNLTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTNLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVDDPIVARGLKAVDNFATE
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAIIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKGVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSGCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A7C7CJ59|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
MNVRLRRNDDLNSTAKHTHSEFAGLNPAIGQATEYLLHLQYPEGYWWSELESNPTMEAEF
LLLTHFLGIGDDNTWRKLSKQLLAQQRPDGTWGQFYDAPGDLSTSTECYFALKLAGVSPD
EPMMKKARDFILSKGGVPETRVFTKIWLSMFGQYEWRGVPVMPPEIMLLPNWFPITIYDF
SSWARATIVPLLIVIDRKPVKSIPESAQIDELYPLARSETDYSISRPNKLIGWETFFYTG
DQVLRHIERLPWKPTRAQAIKKAEQWILDHQETDGSWGGIQPPWVYSLMALHELGYEPDH
PVMKKGIEGFRSFSIEEDDKLKVQACVSPLWDTCLTMIALLDAGVDPEHPALTTAGDWLV
DEQILTGGDWQVKAKNVAPGGWAFEFHNSTYPDLDDSSEIVMALNRVKLSSTESKNQAID
RAVQWLLGMQSSNGGWAAFDKNNTKMLVAKIPFSDFGETIDPPSVDVTAHILEMLGQLGY
RPDHPAVAKGLDYVLADQEDDGPWFGRWGVNYIYGTGAVLPALKALGLNMDVESVRRAVR
WVIDHQNDDGGWGESCVSYVDPEWRGKGPSTASQTAWALLSLLAAGEIDHPATINGVEYL
IRTQQPDGSWDEPYFTGTGFPGYGIGQRLDEPVPEGQPGYPDHEMPAGFMINYHMYRNCW
PLSALGRFRELSNNDDHWPTLGDREAVASEAGEYSPKRAGNRLQRFLKIW
>A0A7H5K4Q3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. S1A1-3|TrEMBL
MTATTDGSTGALPPRAAAASEIHPETTPVAAGTVETRDVATHAIQRATDFLLSRQDAEGW
WKGDLETNVTMDAEDLLLRQFLGIRDETTTRAAGLFIRGEQREDGTWATFYGGPGELSTT
IEAYVALRLAGDAPDDPHMARAAAWIRERGGIASARVFTRIWLALFGWWKWDDLPELPPE
LIYFPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDAGDPNPVKPLAP
AASWDGVFQRLDKALHQYRKVVPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVI
ALHLLGYDLQHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPAD
HPQLVKAADWMLGEEIVRPGDWAVKRPHLPPGGWAFEFHNDNYPDIDDTAEVALALRRVR
HHDPERVEHAIGRGVRWNLGMQSKDGGWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVT
AHVVEMLAVEGLSHDPRTRRGIEWLLAHQEPDGSWFGRWGVNYVYGTGSVLPALVAAGLP
ASHPAIRRAVAWLETVQNDDGGWGEDLRSYHEVAEWSGRGASTASQTGWALLALLAAGER
ASKTVERGIAWLAETQLADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEP
SFVHGESFAEVKGG
>A0A4Q3C9M9|squalene-hopene cyclase|EC 5.4.99.17|Sphingomonadales bacterium|TrEMBL
YCQPCLSPVWDTALAAHAMLEVGGEAAETRARRALEWLKPLQVLDVKGDWADERPDVRPG
GWAFQYNNAHYPDLDDTAVVAMAMDRANVDSDREPIERAVEWTFGMQSGDGGWGAFDADN
VHHYLNDIPFADHGALLDPPTVDVSARCVSMLAQLGYGQDDRRMKTALAYLEREQEHDGS
WFGRWGVNYIYGTWSALSALNAARIDPQAPAMRKAVDWLVKIQNQDGGWGEDCESYALDR
TGHNPAPTTASQTAWALIGLMAAGEVDHPAVARGIAWLQANQDADGLWAQEYYTGGGFPR
VFYLRYHGYPKFFPLWALARYRNLKRGNASHVAWGM
>M1YX70|squalene-hopene cyclase|EC 5.4.99.17|Nitrospina gracilis (strain 3/211)|TrEMBL
MQNSNLKNLQPEATNPEAPAQVENDRARLDTAIARSCQHHFSTQYPEGYWVEELESNVTI
TAEYVFLMHFLGLDQPERKERIKNYLLAQQQEHGGWTLYYGGPPDIGTTVEAYVALKMCG
LPLDAPEMAKARQCIFSLGGVRKARVFTKIFLAMLGQIDWKWTPATPVEAVLLPTWFYFN
IYEMSSWSRGTVVPLSVVCSMKPVWPLPTEQSVPEIFTGADRDMGVKNRNPGLNWSSAFM
LADRVLKLLGKSSWKPFRKIAMRRAEKWILKHQEPEGDFSGIQPAMFNSVLALNLMGYPM
DHPAIVKGMESIDRFFIRQGDQEWMQACVSPLWDTAISCNALMDAGVPGDDPRIVKAIEW
MMKKQVTRGGDWQIKNPHTPPGGWAFEFYNEAYPDTDDTAEILMSIHRTAISDTEWKERE
FQRALTWLMSMQSSNGGWGAFDRDNDHELFNEIPFADHGAMLDPPTVDVTGRILWMLGRI
GHDPKDPRVEHALTFIRDSQEREGCWFGRWGVNYIYGTWLVLMGLSSIGEDMQSSMVRRA
VDWLNSRQNADGGWGETCYSYSDYEYAGKGDSTKSQTAWALMALVEAGEAQSEVVRRGVN
YLITTQQDDGSWYEDEFTGTGFPEHFYIRYHMYRQFFPLMALARYRHVLDHGTVPPRTAP
NTG
>A0A7W1SZ34|squalene-hopene cyclase|EC 5.4.99.17|Acidobacteriales bacterium|TrEMBL
GEAGVPADDPRMVKCADWILQKQVRTTGDWRVKNPEGQPGGWYFEFNNEFYPDVDDSAMV
CLALSHVEHPNGRYQRESVQRAIDWILSMQCKNGGFASFDKDNDRMVFQYIPFADHNAML
DPPTVDITGRILEMLAAYGYTKDHPAVRRAIKFVQDEQESDGSWFGRWGVNYLYGTALVL
RGLEAIGVDHHEPFIQQASEWIRMVQNPDGGWGETCGSYDDPTTKGVGPSTPSQTAWAIL
GLIAASDIQTESVARGIAYLLRTQEQEGSWSEPFYTGTGFPRVFYLKYHMYRQYFPLLAL
TTYKKVVEQSEAS
>B1FBJ5|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia ambifaria IOP40-10|TrEMBL
MIRRMNKPAPSPWSALDTAIARGRDALMRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDARQEKMARYLRAIQRLDTHGGWDLYLDGDPDLSCSVKAYFALKAAGDSEHAPHMVRA
RDAILKLGGAARSNVFTRILLATFGQVPWRATPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNIAIPELFVTPPDQERQYFPPARGMRRAFLALDRVVRHVEPL
LPKRLRQRAIRHAQAWCAERMNGEDGLGGIFPPIVYSYQMMDVLGYPDDHPLRRDCENAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVAVPEAGAPAGALDELDARIARAY
DWLAERQVNDLRGDWIENAPADTQPGGWAFQYANPYYPDIDDSAVITAMLDRRGRTHRNA
DGSHPYAARVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRADDRASLARAIDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALAGED
PSQPYIARALAWLRARQHADGGWGETNDSYIDPALAGTNAGESTSNCTAWALLAQMAFGD
GESESVKRGIAYLQSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GGASSAGAHTVPASTGADAALA
>A0A0E1UCF4|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia pseudomallei Pakistan 9|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A375FG99|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus taiwanensis|TrEMBL
MSMNETALANAAPHTDAAQREPAGPAQAPATRLSAPALDHGIGRALDALLHQQRPDGHWI
YELEADATIPAEYVLMVHYLGEAPDLDLEARMARYLRRIQNPDGGWPLFHQGRSDVSASV
KAYFALKMAGDDPQSAPMQRARQAIHAMGGAEATNVFTRTLLALYGVLPWKAVPMMPVEI
MLLPRWFPFHLSKISYWARTVIVPLLVLNSLRPQARNPRGIGINELFVGNCHTVGLPPRA
PHQHAGWYTVFRGLDALLRVAEPLLPRTLRRRAIAAAQRFVRERLNGEDGLGAIFPAMAN
SVMMFDVLGVPPDDPARAVARRSLERLLVEHGDEAYCQPCLSPVWDTALATHALMETGEV
RAAQAAGRALDWLRPLQVLDLRGDWAVRRPLVRPGGWAFQYANAYYPDVDDTAVVAAAMD
RFMRAHDAPGRYGEAVARATEWIVGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDPP
TADVSARCLSMLCQTGATPGKSEPAARALRYLLAEQMPDGSWFGRWGTNYIYGTWSALCA
LNAAGLPPAAPELQRAVAWLARIQNADGGWGEDGSSYRLDYRGYEPAPSVASQTAWALLA
MMAAGAAQHAAVARGIDYLLRTQQPGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWALA
RYRNLQRGHADHSGHSGQVSWGL
>A0A3P0C6W6|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia anthina|TrEMBL
MIRRMNKTAPSSWSALDTAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDVRQEKMARYLRANQRLDTHGAWDLYVDGAPDVSCSVKAYFALKAAGDSERAPHMIRA
RDAILKLGGAARANVFTRILLATFGQVPWRAAPFMPVEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNVSIRELFVTPPEQERQYFPPARGMRRLFLALDRAVRPIEPL
LPKRLRQRAIRHAEAWCAQRMNGEDGLGGIFPPIVYSYQMMQVLGYPDDHPLRRDCENAL
DKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVAAPETGESAGALRELDARIARAY
DWLAGRQVNDLRGDWIENVPAGVEPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRTHRHA
DGTNPYASRVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVAKRADDRASLARAIDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALAGED
KSQPYIARALDWLRARQHADGGWGETNDSYIDPKLAGTNGGESTSNCTAWALLAQMAFGD
CESDSVRRGIAYLLSVQQEDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GAKDAGATTSSASGAPAPRATDSALA
>A0A2N9N9L4|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Sulfotelmatobacter sp. SbA7|TrEMBL
MHLHWAKKRISWRNFFLVLDRITHWAERLYIRPLRSLALRRAERWMLERFEMSDGLGAIY
PSMMNAIIALRCLGYSVDDPQFIRAMDEFEKLGIEEGDTFRMQPCLSPVWDTAYALFALG
EAGVPASDPRLVKCADWILQKQVRKPGDWKVKNPKGEPGGWYFEFNNEFYPDVDDSAMVC
LALSRVDHPNGRYQSESVQRAIDWVLSMQCKNGGWASFDKDNDRMVFQYVPFADHNAMLD
PATVDITGRILECLATYGYDQNHPAVQRALRFIRKEQEPDGSWFGRWGVNYIYGTMQVLR
GLEAMAVDRNDPMIQQAAEWLRSVQNADGGWGETVGSYDDPNLRGQGDSTASQTAWAIMG
LLAVGDTRSECVARGMAYLLRTQNKDGSWDERFYTGTGFPRVFYLMYHLYREYFPLLALT
TYSKVMAEKSTN
>A0A367PGB0|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus necator|TrEMBL
MSMNETAFATAVPRIAPASAGDSPSPRGAAQALDHGIGRAIDALLHQQRPDGHWVYELEA
DATIPAEYVLMVHYLGEAPDLELEARLARYLRRIQNPDGGWPLFHEGRSDVSASVKAYFA
LKMAGDDPQAAHMQRARRAIHALGGAEASNVFTRTLLALYGVMPWSAVPMMPVEIMLLPQ
WFPFHLSKVSYWARTVIVPLLVLNSLRPQARNPRGVGINELFVGNCHTVRLPPRAAHQHA
GWYTVFRGLDALLRVAEPLVPRTLRRRAIAAAQAFVRERLNGEDGLGAIFPAMANSVMMF
DVLGVPPDDPARAVARQSIERLLVEHGDEAYCQPCLSPVWDTALAAHALLETGEARATAA
AGRGLDWLRPLQVLDVRGDWVVRRPRVRPGGWAFQYANPYYPDVDDTAVVAAAMDRHMRA
HDVPGRYDEAVARAAEWIVGMQSGDGGWGAFEPENTHLYLNNIPFADHGALLDPPTADVS
ARCLSMLCQIGATPAKSEPAARALRYLLAEQMPDGSWFGRWGTNYIYGTWSALCALNAAG
LAPEAPEMRRAVAWLEQIQNADGGWGEDGSSYRLDYRGYEPAPSVASQTAWALLALMAAG
AAQHPAVARGIDYLLRTQQSGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWALARYRNL
QRGGAHQVSWGL
>A0A0N1FYA9|squalene-hopene cyclase|EC 5.4.99.17|Actinobacteria bacterium OK006|TrEMBL
MTATTDGSTGALPPRAAAASEIHPETTPVAAGTVETRDVATHAIQRATDFLLSRQDAEGW
WKGDLETNVTMDAEDLLLRQFLGIRDETTTRAAGLFIRGEQREDGTWATFYGGPGELSAT
IEAYVALRLAGDAPDDPHMARAAAWIRERGGIASARVFTRIWLALFGWWKWDDLPELPPE
LIYFPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDAGDPNPVKPLAP
AASWDGVFQRLDKALHQYRKVAPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVI
ALHLLGYDLQHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPAD
HPQLVKAADWMLGEEIVRPGDWAVKRPHLPPGGWAFEFHNDNYPDIDDTAEVALALRRVR
HHDPERVEHAIGRGVRWNLGMQSKDGGWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVT
AHVVEMLAVEGLSHDPRTRRGIEWLLAHQEPDGSWFGRWGVNYVYGTGSVLPALVAAGLP
ASHPAIRRAVAWLETVQNDDGGWGEDLRSYHEVAEWSGRGASTASQTGWALLALLAAGER
ASKTVERGIAWLAETQLADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEP
SFVHGDSFAEVKGG
>A0A3A4NT40|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Omnitrophica bacterium|TrEMBL
MALNPGIPISDTDISCTSDFAQAVLNAIQSTQQFFLSTQTSAGYWSAYLEADSTLVADYI
MLARYIGHESPVLEQKAVRRLLNTQLDDGGWNIYYNGPSELNATVKCAYALQLAGMSSSH
EALIRAKDCILRHGGLAKVNSYTRFYMGLFGSYPWKKLVSIPPELMFLPTSFYFNIYEIS
SWSRAILVPMSIIWSHRPIKTPPPTVDCGSWWLPKNQEANGKNLRNTISWKTFFFTMDAI
LKRSHRFYSPFTRRESLRRAERWMLEHMSRGGGLAAIYPAMLNSIIALDCLGYDHDHPTF
QHALDEFMKLMVEEDDVLWFQPCFSPVWDTAMVTASLERSGMPSDHPAIQRSAEWLINQE
IGIRGDWQVKNPYGPASGWVFEFENDFYADTDDSAMVLMALHGSRIPLDARRKASMKRGV
EWVLSMQSSDGGWGAFDVDNSKEILNMVPFADHNALLDPSTADVTARILEMLGVFGYDES
FSPASRAVSFLRSQQEKDGAWYGRWGVNYIYGTWQVITGLVRIGVSPADPCIQRGVEWLL
KHQNSDGGWGETVATYDDPSLRGQGDSTPSQTAWALMGLMYGGAIRQDAVKRGIQYLLEN
QMPDGSWKEEHFTGTGFPRVFYLRYTFYRNYFPLMALGFYRSLMRL
>Q39LV3|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MIRRMTTPTPSPWSALDTAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDLRQEKMARYLRANQRLDTHGGWALYVDGDPDVSCSVKAYFALKAAGDSEHAPHMVRA
RDAILKLGGAARANVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNISIRELFVTPPDEERQYFPPARGMRKLFLALDRTVRHVEPL
MPKGLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYCYQMMEVLGYPDDHPLRRDCENAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVAVAEDGEPGDARRALDERITRAY
DWLAERQVNDLRGDWIENAPADVQPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRTHANA
DGTNPYATRVARALDWMRGLQSRNGGFGAFDADCDRLYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRADEHASLARCIDYVKRTQQPDGSWWGRWGTNYIYGTWSVLAGLALAGED
KSQPYIARAIEWLRARQHADGGWGETNDSYIDPKLGGTNGGESTSNFTAWALLAQMAFGD
CESDSVKRGIAYLQSVQQEDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GVANKRVSTADKTADAMA
>A0A6N6JQ49|squalene-hopene cyclase|EC 5.4.99.17|bacterium|TrEMBL
MRCGVVRRGLAAILAPMSKAHQTLHRELTRKKGGSHRKIRNILHELEGLDVLLDKFSAHP
RRADKSNDPALDAAIARQQSRMLAIRDKGEVYWNAELDSNAGLGAEYIMMLHFLGIAGQP
SFAERQRKIANYTRQWQNDDGSWSIYARGPGHLSYSVTCYFGLKLAGDSPDAPHMVKARE
WIRAHGGAMPIGVEQRFLLALFGQYDWAGVPPIPSWMVLLPHLPMLPRALENKLLNIYDL
SYWCRISLVPMSVLYQLKPLVRIDERLGVEELFLEPRDQRRWSFAPVSEPGLMSWGGLFN
VGAKAVKALEFATNGVVAKVALNKAQKWILDHQDDSGDWGGIYPPIMYNIMALSRLGMPL
SDARIVKAFKALDRFMIYHARCDGLHVQACVSPVWDTAWALYALGESGYDIRDTEFQRGI
DWLYSRQILRDGDWAVKNPNAIPGGWCFQFYNDFYPDLDDTAIVLQALLFGGYPRGQAGR
VEQTRIGLEWVLSMQNQDGGWSAFECGVDKALVNHIPFNDLNNMLDPSTADVTGHVLEML
GHFGFDLGFAPCRRAAEYLRKTQERDGARAGSWWGRWGVNYVYGTWSALAGLAQVGEDMS
KPYVRQAVAWLYGVQNPDGGWGEGCETYKEPERAGREISGQSTPSQTAWALLGLLAAGEV
DDARLRRGVEWLLTRQLPQGGWDEELFTGTGFPNAFYLNYHFYREYFPLLALGRYRNARC
GLKPI
>A0A330L2T4|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira lenta|TrEMBL
MKLFRTLFDRISSSLLATIPGKYNPAIGYAQAPPLRLVSDKITPLAAPDLSRRPSAHTVS
QPDAIDDAIRRSQSWFLSKQDPAEGFWVAELEADTTLTSEYLMLRRFLDCVDPVKEERAV
KYLRTMQLPDGGWPIHYGGPAEISASVKAYFALKLSGVPATDPCLLRAHERIMVMGGVVQ
ANVFTKIALALFDQYDWEGVPHMPVEIMLLPKRFYFSIYAISYWSRAVLIPLLIVFAHQP
VCRIPREQGIEELYLVPRGQVPYWKYPPFNKDQAWFTPHNFFVMLDAVLKLYDRMPLLWL
REKAMHKAATWMLDHLKGSGGLGAIYPAMANSVLALRCLGYEMDDPLVQKALREIEELEV
YDTATLDGQRVATLHLQPCHSPIWDTALLMNALSEAGMPQDHPALVKAGAYLMSRQTKAV
GDWTISSPQAEPGGWYFQFENELYPDVDDSAVVLMALAKLKMPEPADLRESIRRGMQWVL
AMQSSDGGWGAYDKDNNRVVFNYIPFADHKALLDPSTADLTGRCLEMLGALGYDRSHPAA
QSALAFIKKEQEADGSWYGRWGVNYIYGTWSVLAGLRAIGEDVSSPYIRRAVSWLESKQN
PDGGWGEACHSYAEEAHSGKGQSTPSQTAWALMALMSAGVTESLSIARGVQFLLRHQLKD
GSWEEVMHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRSRGRMRSEELQEQVESSGCY
RFDH
>A0A515YIX1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. RLB3-6|TrEMBL
MTATTDGSTGALPPRAAAASEIHPETTPVAAGTVETRDVATHAIQRATDFLLSRQDAEGW
WKGDLETNVTMDAEDLLLRQFLGIRDETTTRAAGLFIRGEQREDGTWATFYGGPGELSTT
IEAYVALRLAGDAPDDPHMARAAAWIRERGGIASARVFTRIWLALFGWWKWDDLPELPPE
LIYFPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDAGDPNPVKPLAP
AASWDGVFQRLDKALHQYRKVVPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVI
ALHLLGYDLQHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPAD
HPQLVKAADWMLGEEIVRPGDWAVKRPHLPPGGWAFEFHNDNYPDIDDTAEVALALRRVR
HHDPERVEHAIGRGVRWNLGMQSKDGGWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVT
AHVVEMLAVEGLSHDPRTRRGIEWLLAHQEPDGSWFGRWGVNYVYGTGSVLPALVAAGLP
ASHPAIRRAVAWLETVQNDDGGWGEDLRSYHEVAEWSGRGASTASQTGWALLALLAAGER
ASKTVERGIAWLAETQLADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEP
SFVHGESFAEVKGG
>A0A2X3MM06|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Bipolaricaulis anaerobius|TrEMBL
MPDHAPVAGLDHAIDRAVGWLLSHQYPAGYFWGELESNATITAEHLFLTHILGVGSPELW
DKIARYILGQEREDGSWANWYGGPGDLSTTVEAYLALKLAGVDPASEEMEWARGWILSQG
GVEKARVFTKIWLALLGEWPWEATPMLPPELVLLPSWFPVNLYSFASWARGTILPLAILR
VKRPVYPIPEHARIDELFLRGRGNADHSLPRKKSAWGRFFSAADKLLRAYERAHIRPLRR
LALKRAEEWIVERQEADGCWGGIQPPWVYSLIALHALGHPWESPVMRKGVAGFDRYAIEE
EGTWRLQSCISPVWDTGLAMIALHDAGLPEDHPALVKAGEWLLGEQIFVGGDWQVKCTAR
PGGWAFEFDNDIYPDTDDTSVVLMALQGTELSEEAKEFALSRGRDWLLGMQSRNGGWGAF
DRNNTQVFLREIPFADFGELVDPPSVDVTAHIVEFLGRMGYRPGFRPLDRALRYMFREEE
PDGPWYGRWGVNFIYGTGYVLPALQACGFPLDDPRVRRAVGWLLARQNEDGGWGEDVLSY
HEPELRGRGPSCASQTAWALLALLAAGEEEGEAVRRGIAYLVRTQREDGTWDEPYFTGTG
FPTDFMIRYHLYRHVFPLMALGRAREGQ
>A0A839T5C6|squalene-hopene cyclase|EC 5.4.99.17|Azomonas macrocytogenes|TrEMBL
MESSSLLASAIADSDSRDFEATDLDQAIERAREALLALQQPDGHWCFEFETDCTISAEYI
LMMHFLDEIDDVLQEKLARYIRLKQRQDTHGGWPLYQDGALDLSCTVKAYYALKAAGDVP
EMPHMRRAREAILAQGGAAKSNAFTRILLAMFEQVPWRAAPYVPVEIMLFPRWAPFHLDK
ISYWARTTMVPLLILCSLKARAKNPRNVDVRELFVVPPEQERHYFSSKGFVNKLFLVLDK
LGRACDPLIPNSVRQKAVKKAEQWFLPRLNGEDGLGAIFPPMVNALEAMTLLGYPKDHPA
RATCLKSLQKLIVDRGDGTAYCQPCVSPVWDTGWAAMALLRASSDEATQAAVTRALDWLA
PLQELELKGDWAAQAPDLAPGGWAFQYANAYYPDLDDTAVIAGLMHVAQRNTGEPEKYRE
RIERAADWLVGMQSDNGGFAAFDRNNTHYHINQIPFADHGAMLDPPTEDVSGRVLAFLGV
LKREQDNEAIRRCVAYLQQAQLPDGSYWGRWGTNYIYGTWSVLAGLSLIGEDMSQPWIRK
SIDWLKAKQHADGGWGETNDSYLDPTLRGSNGGVSTAHTTAWALLGLLAAGEYACEAVRR
GIQWLLDDQQAAGEREAGLWYHPSYNAPGFPRVFYLKYHGYTAYFPLWALVRYRQLSSGS
RSQS
>A0A0N7Z4G8|squalene-hopene cyclase|EC 5.4.99.17|Leptolyngbya sp. NIES-2104|TrEMBL
MQSLENAISASQQYLLSLQKPEGYWWAELESNVTITAETILLHKIWGTDQERPLHKAENY
LRSQQRIHGGWELYYNDGGDLSTTVEAYMALRLLGVSSADPALVRAKEFILARGGITKTR
IFTKFHLALLGCFDWRGIPSLPPGIMFLPSIKVEIPNPFGDPLFSGHTFSIYEMSSWARG
STVPLLVAFDRKPVFITDPAVTLDELYVEGVHNAVYELPRKSDWTDLFLDLDRAFKFAED
WNLMPFREEGIKAAEKWILERQEATGDWGGIIPAMINSLIALRCLGYDANDPFVARGLRA
IDHFAIEEDNSYRIQPCVSPVWDTGLVIRSLIESGVSPSHPELVKAGEWLLEKQILSYGD
WAVKNTEGKPGAWAFEFENRFYPDVDDSAVVVMALDLLEMPNEAEKQQAIVRCVNWISTM
QCKPGGWAAFDLDNDQDWLNAMPYGDLKAMIDPNTADVTARVLEMLGQLQNGDPKRTAAL
TPEKLDRALSYLVREQEADGSWFGRWGVNYIYGTSGVLAALSKVAPNTHRRSIERGANWL
TQVQNPDGGWGETCESYKDLTLKGKGDSTASQTAWAIIGLLAAGDGIGQYEWEAIDKGIA
YLIQTQKDGAWDEDLFTGTGFPGHFYLKYHLYQQHFSLTALGRYQTSLKQRSTLKVPLNL
KIKEPVLELGE
>A0A4S2V539|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. A0642|TrEMBL
MTATTDGSTGAVNPRAASASIPTTESTIAADDVLAAARRAAERSVEHLLGRQDEQGWWKG
DLATNVTMDAEDLLLRQFLGIQDPATVRAAGRFIRGEQLGDGTWATFHGGPGDLSATIEA
YVALRLAGDRPDEPHMARASGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMF
FPKWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPATPNPPRRPAPAAS
WDGVFQRLDKALHLYHRIAPRRLRRVAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLDHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLAPDHPA
LVKAADWMLGEEIARPGDWSVRRPQLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPE
QPKVEAAIERGVRWTIGMQSRNGAWGAFDADNTSAFPNRLPFCDFGEVIDPPSADVTGHV
VEMLAIEGHSGHPATRRGIEWLLAEQDAAGGWFGRWGVNYVYGTGSVVPALLAAGMSASH
PSIRRAVGWLESVQNDDGGWGEDLRSYHDDKWIGHGASTASQTAWALLALLAAGRRETAA
VARGIAWLAETQQPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFAGR
AAVREGA
>A0A7J9YQ00|squalene-hopene cyclase|EC 5.4.99.17|Solirubrobacterales bacterium|TrEMBL
MNATSPSQVPVPGALDEDLPSSPRARPQALGAEGALARATERLLSLQDRQGWWRGELETN
VTMDAEDLLLREFLGIRGERETHLAANWIRSQQRDDGSWAVFHGGDGDLSTTIEAYTALR
LAGDSSGADHMGSARTFILAHGGIERARVFTRIWLALFDLWPWDELPALPPEIMFFPSWV
PFNIYDFACWARQTVVPLSVVMAMRPRRPLDFGLDELRVGARPAAPRRGLRTRARRMALL
DSAARLYGKAAPRVVRRAALRRAERWILARQEADGSWGGIQPPWVYSLLALQLLGYETDH
PVMRAGLDGLERFLVHDRDVRRLEACQSPVWDTALAIIALADAGVPADDSALVRAADWLL
GEEVRVPGDWAVRRPHVPPGGWAFEFANDNYPDLDDTAEVILALRRVVHPQPDRVEAAIA
RGLAWALGMQSADDGWASFDADNTRGSLRELPFSDFGEVIDPPSADVTAHVIEMLAREGH
GSQPAVKGGLLRLSDWQEADGSWFGRWGVNHTYGTSAVLLALEAAGVPRDDPRVRRAVRW
LEDHQNADGGWGEDPRSYEDPAWIGRGPSTASQTAWALLGLHAAGQRSAAAERGIAWLAS
TQRRDGSWDEPEFTGTGFPGDFYINYHLYRLVFPVMALGRWCGDGTSVERATHRPQAVRE
PAEGER
>A0A7H0I101|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces genisteinicus|TrEMBL
MTATTDGSGGPPRAGSAAAELRTTREPLAPAPHDLDEIAARAAERAAEHLLARQDAEGWW
KGDLETNVTMDAEDLLLRQFLGVRDEATTEASARFVRGQQRDDGTWASFYGGPGELSTTV
EAYVALRLAGDRPDDPHMQRAASWIRGQGGIAASRVFTRIWLALFGWWKWDDLPELPPEL
IFLPKWFPLNIYAFGCWARQTIVPLSVVSALRPVRPAPFALDELHTDPDDPSPPAPLAPA
TTWDGLFQRADRALRLYRRAAPRRLRRTAMNSAARWIVERQENDGCWGGIQPPAVYSVIA
LHLLGYDLGHPVMREGLASLDRFAVWREQDGRPVRMIEACQSPVWDTCLATVALADAGVP
ADHPALVKAADWMLGEQVVRPGDWSVRRPQLGSGGWAFEFHNDNYPDTDDTAEVVLALRR
VDHPEPARLDAAVARGVRWNLGMQSRNGAWGAFDADNTSTLPNKLPFCDFGEVIDPPSAD
VTAHVVEMLAHEGMADHPRTRRGIQWLLSEQEPNGAWFGRWGVNYLYGTGSVVPALVAAG
MPTAHPAIRRAVGWLRSVQNDDGGWGEDLRSYRERGAVGRGTSTASQTAWALLALLAAGE
KDGTAARRGIAWLASAQRPDGTWDEPEFTGTGFPWDFSINYHLYRHVFPLTALGRYVHGE
PVVGAAARRGR
>H6SNY5|squalene-hopene cyclase|EC 5.4.99.17|Pararhodospirillum photometricum DSM 122|TrEMBL
MALFFTKTTFFGRRRAAPCSHAANPALRVSMDAMMDASVYLRETGAPATEGNPVGDGELN
AIIDEATRWLTDRQNADGHWVFELEADATIPAEYILLNHFLDEIDDEREHRLARYLRRIQ
GKHGGWPLFHDGDFDMSASVKAYYALKLVGDSVEAPHMRRARAAILAHGGAERANVFTRF
TLAMFGQVPWRACPVTPIEAVLLPRWSPFHTTKVSYWSRTVMTPLMVLYSRRARAINPRG
IGVQELFRRNPEDVRDWMKNPTGHWIGETLIQVDKVLRVIEPAVHRLFRGKAEAWALDFI
EKRLNGKDGLGGIYPAIANTLMVYQTLGYAKDHPHYRIAREAVDGLCVRHGDIEYVQPCL
SPVWDTCLASHALQEAGLKANDPAIAKSNEWLRGRQVLSVVGDWAHNRGHLEPGGWAFQY
WNDYYPDVDDTAVVVMALDRANEGDVNREAIKRAEAWIKGMQSANGGWGAFDAENNTEFL
NHIPFADHGALLDPPTVDVSARCLGMLAQIGCPLTDPVVQKGVEFLWSEQEEDGSWFGRW
GTNYIYGTWSALNALNAVDVDMQDPRVRKAVQWLKDRQQPDGGWGEDCATYWKERKGEVK
GSTPTQTAWAVLGLMAAGEVDSPEVERGIRYLLDAPRDGGKWQEELYNAVGFPRIFYLRY
HGYSAYFPLWALARYRSLSQGNSKFPLTGM
>A0A7C2ZBU2|squalene-hopene cyclase|EC 5.4.99.17|Acidobacteria bacterium|TrEMBL
MAHGTQIGFELPTEPAQFEARLKAAIERGVEHLLALQTPEGYWHAELEADTTLESDYIFY
LHLLGKADPERVAKLANYVRRRQLPDGGWNIYYGGPAEVNATVKAYVALRLAGDAAEAPH
MQRAAERVRALGGLERTNSFTRFYLAMAGAIEWEKVPAIPPELMLAPDWFFLNIYEMSSW
TRAIVVPMMILYAQKPSWRLPAGVRVDELYRDPARQIPSFAWDRELFTWRNLFLAADRVF
KLYERLPWKPLRRRALRAAERWMFEHLERSDGLGAIYPAMMNSIFALLALGYGADDPLTA
REVRQLARFEIEEDDTIRVQPCLSPVWDTCIAMVALEEAGLPPDHPALVRAAGWLLDRQI
LGPGDWQKKCDGRPGGWAFEFRNDFYPDVDDTAFVLMALQRVDYPDRSRFEQAIRRGIEW
LLSMQNRDGGWAAFDKNNDRWVLTQVPFADHNAMIDPSTADVTARALECLGRYGWPAEHP
VIQRAVSFLRRDQNSDGSWYGRWGVNYLYGTGGVLRALEPLGLAARDFARRAVEWLRGVQ
NPDGGFGESIASYDDPSRKGQGTSTPSQTAWALIGLLAAAAPEPNARCSDPAVVRAIEYL
LATQKPDGSWEEAEFTGTGFPRVFYLKYHLYRNYFPLYALARYRNLLSGAEPFCAVKLGP
DARTPGGPREAGQ
>A0A0D8B9C0|squalene-hopene cyclase|EC 5.4.99.17|Frankia torreyi|TrEMBL
MSLTSDPSPAAPTAEKSPKRPTIPVPATADAYGISRSSPPLPAGTGRPHTAGPINAGVAA
ARARDHLLALQSDEGWWKGDLETNVTMDAEDLFMKQFLGIRGDDETEQTARWIRSQQLAD
GGWPTFYGGPADLSTTIEAYIALRLAGDAVDAPHMARAAELVRAQGGVAASRVFTRIWLA
ALGQWSWDDVPVIPPELIFLPSWIPLNVYDFACWARQTIVALTIVGSLRPSHDLGFTIDE
LKVPAAGRKPAPLRSWEGAFERLDKLLHRYERRPIKLLRTLALRRATEWVVARQEADGCW
GGIQPPWVYSVMALHLMGYPLNHPVIATAFRGMERYVIRRDTPEGPIRQIEACQSPVWDT
ALAVVALADAGVPGDHPAMVKAGRWLVDEEVRVAGDWAVRRPELAPGGWAFEFDNDFYPD
VDDTAEVVLALRRLLGAGHVAPPASRQGRAEAPSVNTVEDADPRLAAAMRAAAARGVDWS
VGMRSSNGAWGAFDADNVRTLTTKIPFCDFGEVVDPPSADVTAHIVEMLADLGRSDHPIT
QRAVQWLLDNQEPGGSWFGRWGVNHLYGTGAVVPALIGAGVPTDHPAITAAVRWLLEHQS
PEGGWGEDLRSYTDPAWIGRGELTASQTAWALLALLAVDPHSLAVKRGVRWLCETQRPDG
TWDEPYFTGTGFPGDFSLNYHLYRLVFPLTALGRYVGLTGVATP
>A0A7C5NCM4|squalene-hopene cyclase|EC 5.4.99.17|Polyangiaceae bacterium|TrEMBL
MSPAVSTQVRDEVVAATLRARGHLLGLQDKGGFWRGELETNVTMDAEDLLLRAFLGISDD
ALTQRSARWIRSRQRTDGAWDNAHLGPPDLSTTVEAYVALRLAGDPIEQKHMRRAAAFIR
AHGGLPATRVFTRIWLALFGLWSWDDLPTLPPELMLLPPSAPLSAYSFASWARQTIVALS
VVMTVRPQRSLGIDLLELSSDRAELGCEGLGCEGLGCEGLGCDPAPPTLAGRAFAVIDAA
ARWYLRAPVHPGRERALLAAEQFIVSRQEADGSWGGIQPPWVYSIIALSLRGYPLSHPVM
RAGIEGLSRFTIDDGETRRMEACQSPVWDTALAVLALVDAGCDPGDSALVQASDWLLTQQ
VDQRGDWSVRRPALRSGGWAFEFENVNYPDVDDTAEVMLALRAAGSSNPQETETALARGA
TWVLGMQSDGGGFGAFDADNTNRLVRHIPFCDFGEVIDEPSADVTAHAVEMLVAEGFKAH
PKTRAAVRWLVDHQEADGSWFGRWGVNYVYGIGAVLPALVAAGLEDRRPIDRAVAWLESH
QNADGGFGEGVCSYGDKAMRGVGPSTPSQTAWAMLALLAADSGDTALARAADYLVGCQRS
DGGWDEDAFTGTGFPGDFYIRYHLYRDIFPTMALGRYARALGWRPRARSGRVVLPQVSAA
AESRAAEAAE
>A0A853AS94|squalene-hopene cyclase|EC 5.4.99.17|Saccharopolyspora hordei|TrEMBL
MTDQLQQPTRAVVVPDPRTAMVAARDHLLSLQHPDGWWKGELETNVTMDVEDLLLRQFLG
IRTAVETEQAARWIRSQQRRDGTWATFHGGPGDLSTTVEAYTALKLAGDDVDAEHMATAR
AWILEHGGLEATRVFTRIWLALFGEWSWDELPAMPPEVVLLPSWFPLNVADWACWARQTV
VPLTVVCTLRPQRELGITVRELRTGRPRPSTRPAWSWNYAFTVLDRLLHRYHRRPLRSLR
RHAMLRAAEWIVARQEADGSWGGIQPPWVYSLLALHLLGYPLDHPVVRQGLDGLERFLVR
EQTPDGVVRRLEACQSPVWDTVLGVQALRDAGVPSAHPALRRATDFLLAEEIRIEGDWSV
RRPDLPPGGGWAFEFDNDRYPDVDDTAEVLLALNRVDHPNREAVQAAIERGARWLRGMQS
ADGGWGAFDADNTRQLVRKLPFCDFGEVIDPPSADVTAHVVEALATLGHDDEVVRRGVTW
LLRHQEKDGSWFGRWGANHVYGTGAVVPALVKAGLTPEHRALRRAARWLERHQNTDGGWG
EDLRSYDDPAWIGRGDSTPSQTGWALMALLALGRHRTDAVQRGLHYLARTQRADGGWDEP
QFTGTGFPGDFYINYHLYRVIFPLTALGRYVRAGE
>A0A5C8T8K5|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium sp. WL64|TrEMBL
MREAVSKVEPLQRSKTQGISLDDVERGVAQATRALINLAHDDGHICFELEADATIPSEYV
LFHHFRGTPVPEGLEAKIGNYLRRTQGRHGGWALVHEGPFDMSCTVKAYFALKMIGEDIE
APYMRRAREAILSRGGAANANVFTRFMLALYGEVPWRAVPVMPVEVMFLPKWFPFHLDKI
SYWARTTVVPLFVLQATKPRARNPRGISVQELFITPPESVRTWPGSPHATWPWTPIFGFI
DRMLQLVEDRLPRKSRQRAMEKARAWVSERLNGEDGLGAIFPAMVNSVLMYEVMGYRPDH
PQVRVACDAIEKLVVEKADEAYVQPCVSPVWDTALAAHALLEAGSPEAEAQARAGLDWLK
PRQVLDIVGDWAARKPKVRPGGWAFQYANAHYPDLDDTAVVVMAMDRAMHQHGLVAGMPD
YKASIARAREWVEGLQSEDGGWAAFDADNNHMYLNHIPFSDHGALLDPPTADVTARVVGM
LAQLGETRETSRALDRGVNYLLNDQEEDGSWYGRWGMNFIYGTWSVLCALNAAGVDSADP
RIQRSVSWLIRIQNPDGGWGEDASSYKIDPAFEAGSSTASQTAWALLALMAAGAVDDPAV
TRGINFLTRTQGADGFWNEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKRTNSRR
VQFGM
>A0A7X0B1N6|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirillum iridis|TrEMBL
MEADRVGTGAGKARVSEGVLQQAIDRAARVLMDSQAADGHWVFDLEADATIPAEYILLKH
HLGEEPDPEIARRIGNYLRRIQGDHGGWPLFFKGAFNISASVKAYFALKAIGDDIDAPHM
ARARQAIHDNGGAAASNVFTRILLAQFGAVPWTAVPVMPVEIMLLPRWFPFHLTKISYWA
RTVIVPLLVLMACQSKAKNPRNLRIDELFLVPAHQVKSWPKAPHVKKPWGEIFGAIDRVL
RLAQPLFPKKSREKAIEKAVAFTRERLNGEDGLGAIYPAMANTVMMFDLLGWSPKHPEVA
TARYAIEKLLIIDEAADEAFCQPCVSPVWDTSLLCHAMMEVGTDEALERTGKALEWLKGE
QILDVKGDWADQRPNVRPGGWAFQYGNDHYPDLDDTAVVVMAFNRAQPQLAAAGLPADYD
TTVARGAEWVEGLQSRNGGWGAFDADNTHYHLNYIPFSDHGALLDPPTSDVTGRCLGMMA
QLGADKDSPAMKEAVAYLLNEQEKDGSWFGRWGVNYVYGTWSALNGLNAAGLPPEHPAMK
KAVEWLVQIQNPDGGWGEDCESYALDYRGYQPFPSTASQTAWALLGLMAAGAVDHPAVAR
GIEWLTRNQGGDGLWKEEFYSGGGFPRIFYLRYHGYSKYFPLWALARYRNLSNSNSKLVS
VGL
>A0A643GFL0|squalene-hopene cyclase|EC 5.4.99.17|Oryzomonas sagensis|TrEMBL
MHSKTKTKLNVIEGGRGAKQAEAGVSANTFLHVESVLEKAAHQLAALQNDDGHWVFELEA
DVTIPSEYIMLQRFLGRSVDEKTASRLSSYLLDRQLPDGSWPLYAVDGNANISASVKAYF
ALKLLGHDKNAPYMVKARQIILSLGGAARCNVFTRITLALFGQVPWHTPPAMPIEIMLLP
RWFFFHLSKISYWSRTVIVPLLILYAKQPVCALRHDEGITELFTTPPDMLGNLDHFRHRA
WRKNVFIILDRVLKRTMHYIPKRISAHALRQAEQWTRERMQGEGGIGAIYPAMANAVMAL
KTLGCREDDPDYVRGLAALDDLLIHRTPAPDAVPSLQSPFGGGIDRSSAAPDLLPSRHAA
TARDDHFSLCQPCNSPVWDTCLSLSALVEAGIPGNLFSADEAMKWLFDRQISTPGDWSGK
CPGLACGGWAFQYENTLYPDVDDTSKVLMGLFRAGALEREEYREKIAKAVRWVIGMQNSD
GGWGAFDVDNDYLYLNDIPFADHGALLDPSTSDLTGRCIEMLGMLGYGPDFPPIARGLAY
LEEEQEAFGGWFGRWGVNYLYGTWSVLSGLHEVGEDMQKPYVRKAVEWLVGCQNGDGGWG
ETCASYDDPSLAGSGASTPSQTAWALLALMAAGETDRPEVQRGMQYLVDRYHNGWEERHF
TGTGFPRVFYLRYHGYRLFFPVWALGAYLRRRRGATTVQDAVRRKYMGGVSWLKLQ
>A0A552QZS9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. 130|TrEMBL
MTATTDGSTGAVDPRAASASRKTIESTIAADGVLAAARRAAERSVEHLLGRQDEQGWWKG
DLATNVTMDAEDLLLRQFLGIQDPATVRAAAGFIRGEQLGDGTWATFHGGPPDLSTTIEA
YVALRLAGDRPEDPHMARAAGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMF
FPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPGNPNPPKRPAPARS
WDGLFQRIDKALHVYHRFAPRGLRRVAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVMRAGLESLDRFAVWREDGTRMIEACQSPVWDTCLATIALADAGVAPDHPA
LVKAADWMLAEEIVRPGDWAVRRPQLEPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPD
QARVNAAIERGVRWNVGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHV
VEMLAVEGRADHPVTRRGIEWLLSEQDANGGWFGRWGVNYVYGTGSVVPALTAAGLPPSH
PAIRRAVDWLESVQNDDGGWGEDLRSYTEEKWIGQGASTASQTAWALLALLAAGRRDTVA
VTRGVAWLTETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGDPFAGR
TPTREGA
>A0A640XPS1|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Brocadia sp. AMX2|TrEMBL
MRNFLISFFERLETSIHKFNGNGNGNGNGNHPIPELSEHELRFESMPLGAGFHTPLSTKN
PLDITIYRAQQYLLRNQNRSDGHWVGILEADTTITSEYIMLMHFLGKVNQEKQRLAANLL
CEHQISDGGWNIYYGGPSEISASVKAYFALKLAGYSANEPFMQKARKRILEMGGIMKANC
FTKIYLAMFGQVDWQAVPAVPAEMILFPPGFYFSIYEMSYWSRCIVVPLSIAIAKKPHIP
VGDDMLKELYLIPREKVVYRIKRDQSGLSWHNFFIDADSIFRRYEQQPIKFIRRMALRKA
EKWMLDHVEKSGGLGAIWPAMVNSIFAMKCLGYPDDHPALKSQLQEVENLVVYEVNKLYL
QPCVSPVWDTAWAIIALHDSGIPGSDPALQKAGRWLISKEVRNFGDWALKCKVEEPSGWY
FQYANEFYPDTDDSAAVLMALQRVSLPETAHKEASVLRGLRWIMAMQCDDGGWGAFDRNN
NRAILNHIPFADFNALLDPSTSDVTARCTEFLGRIGFSKTSGQIRMAIEFLKKEQEKDGT
WFGRWGANYIYGTWSVLAGLAAVGEDMNKPYIKKAVAWLKSVQNSDGGWGETIKSYDDPF
LKAIGKSTPSQTAWALLGLMAAGEIHSDAVERGIKFLLMKQKEDGSWDEVEFTATGFPKV
FYLKYHMYRNYFPLMALGRYRNSIHNKV
>A0A537DDG6|squalene-hopene cyclase|EC 5.4.99.17|Betaproteobacteria bacterium|TrEMBL
MHSSSREARLTPDPELVARQTPIGPAESSLDRAIETATAALVKRQRADGHWVFELEADAT
IAAEYVVLQHFLGEPNPALEAKIAIYLRRLQGPHGGWSLFHGGGLNISASVKAYFALKLA
GDAPESAHMRRAREAILAQGGAGTTNVFTRILLALFGVISWGAVPIIPVEIVFLPRWFPF
HLSRVSYWSRTVVVPLLVLQALKPRARNPRGVRIDELFPGRRPRARRWARAPHQARARFA
VFAAIDAALRLVEPLIPQRLRRRAIKKAVAFVTERLNGEEGLGAIFPAMANTVMMFDALG
YARDHPHFVTARRAIDKLLVVTREEAYCQPCVSPVWDTVLVCQSLLEVGDNQTRTAARDG
LAWLEKRQVLDAVGDWADQRPHVRPGGWAFQYANPHYPDLDDTAVVVMAMDRFARRRVMR
GEPDFRGAIDRGREWVLGLQSANGGWGAFDVDNTSEYLNHIPFADHGALLDPPTADVTAR
CVSMIAQLGDAADAPVLAKALGFLRRNQEDDGSWYGRWGMNYVYGTWSVLCALSAAGMSP
DAPEIRRAVAWLIAAQNEDGGWGETGDSYRLDHRGLERAPSTASQTAWALLGLMTAGEER
NPAVERGIDYLVRRQGADGFWREPQFTATGFPRVFYLRYHGYAKFFPLWALARYRNLAQS
GERRVRFGM
>K9PE31|squalene-hopene cyclase|EC 5.4.99.17|Calothrix sp. PCC 7507|TrEMBL
MQTQDRVIVNQTAAAIAASQQYLLSIQNPAGYWWAELESNVTITAETVLLHKIWGTDITR
PLHKVEAYLRQQQRNHGGWELFYGDGGELSTSVEAYMALRLLGVPNTDPAMIQARTFILQ
RGGISKTRIFTKLHLALIGCYDWRGLPSLPAWVMLLPPAFPFNIYEMSSWARSSTVPLLI
VFDRKPVFITDPAINLDELYAEGVDQVQFALPRNGDWTDLFITLDHGFKLAESLNLLPFR
QEGINAAEKWILERQEATGDWGGIIPAMLNSLLALRCLDYDASDPIVERGLKAVDNFAIE
TEDSYRVQPCVSPVWDTAWVIRALVDSGFTPDHPAIVKAGEWLLDQQILDYGDWNVKNRQ
GKPGAWAFEFDNRFYPDVDDSAVVVMALHQAKLPNEKLKHAAIARAVNWIASMQCKPGGW
AAFDLDNDQDWLNAVPYGDLKAMIDPNTADVTARVLEMLGAGNLAIDPDNLARAIAYIIN
EQEPEGCWFGRWGVNYIYGTSGVLSALALIDPLKYQLNIKRGAAWLVSCQNPDGGWGETC
RSYDDPSLKGQGTSTASQTAWALIGLIAAGEATGELADHTLEKGINFLLTTQQPDGTWYE
ADFTGTGFPSHFYLKYHMYQQYFPLIALGRYQSVLDNGEWGNKS
>A0A5C7NTV9|squalene-hopene cyclase|EC 5.4.99.17|Rhodospirillaceae bacterium|TrEMBL
MSRQGLASAAAPIAAENLLQRVEQGIAAAAEALGARQHPDGHWAFELEADATIPAEYVLL
KHFLDEIDPGIEPPIVNYLKSIQGAHGGWPLFHDGDFNISASVKAYFALKICGEDVNAPH
MKRAREAILAHGGAQTSNVFTLIQLALFGQVPWHAVPVMPVEIMHLPRWFPFHLDKVSYW
SRTVIVPLLVLMAKKPMAKNPRRVDVRELFVTPPEQVTNWYNMSRKGAWAIFFRNIDRVL
QRTQWAFPKSLRERAIKKAVRFVTERLNGEDGLGAIYPAMANSVMMFEVLGYPKDHPDLV
IAKKSIEKLMIVHGDRAYCQPCLSPVWDTGLASHAVLEIGGEFANRATLAADWLKDRQIL
DVVGDWAVRAPGVRPGGWAFQYNNPHYPDVDDTAVVVMALDRLDHAKYKEQIDRAVEWIF
GLQSSNGGWGAFDADNDYQYLNHIPFADHGALLDPPTADVSARCLSMLAQLGYKTDHPKV
KAALDYLLREQEEDGSWFGRWGTNYVYGTWSVLCALNAIGLPGDHPAMRKASEWLISKQR
EDGGWGEDGASYWEDQPRGEGKVSTASQTAWAVLGLMAAGDVDHPSVEKGIRFLTETQAE
NGEWDEESYTAVGFPRVFYLRYHGYRAFFPVWAMARYRNLKQGNSTNVLFGM
>A0A432M5M8|squalene-hopene cyclase|EC 5.4.99.17|Dyella choica|TrEMBL
MNPFTPKTAAVASDDLFQAAQSSTLDQVIERGRAALLARQHQDGHWCFELESDCTITAEY
ILMMHFMDDIDDVLQEKMARYLRATQAKAKHGGWSQYYGGDLDLSCTVKAYYALKAAGDD
TQAEHMRIAREAILAHGGAAKANVFTRILLALFEQVPWRATPYVPVEIMLLPRWFPFHIE
KISYWARTTLVPLTILCSLKAKAANPRKVHIRELFVTAPEQERHYFVRGGLLNRCFLALD
KLGRSCDRLIPKSLRQRAVKRAVDWFMPRLNGEDGIGAIFPPMVNSLEAMALLGYPKDHP
ARQTCLRSIQKLVVHRADGSAYCQPCVSPIWDTVWSALTLMHTSDDAQTQGAIDKSIDWF
VSKQELELKGDWAVRAPDLKPGGWAFQYNNAYYPDIDDTAVVAALLHIQDRRRGEPGRHR
LNVDRAADWMIGLQSRNGGFAAFDADNTYYYLNAIPFADHGALLDPPTEDVSGRVAAALG
VLGRPQDAQALRRCVDYLRDTQLEDGSWWGRWGSNYIYGTWSVLAGLALAGEDPSQPAIR
KAVQWLRSRQNADGGWGETNDSYIDPALRGTHGGISTSQSTAWALLAQMAVGEVRTESVR
RGIEFLLDHQQPDGFWSNPTHNAPGFPRVYYLKYHGYTAYFPLWALSRYRQLLSSAQA
>A0A3L7MZC6|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MYTVVALKCLGVKESSPEMQWALKQLLDLVIEEKGSIRLQPCVSPVWDTALATIAVADAG
QPQDDLNLRKAVDWLLKKEVTGKIDCSTNYPDMKPAGWFFEYNNQFYPDIDDTAMVIIAL
VKTNSHNRPECIAAIERSVRWIFLMQNRDGGWGAFDKDIDQEFLTKVPFADHNAMLDPTC
PDISARVLEALGELGYRSDEIHIQKAIEYIRCSQEPWGAWVGRWGVNYIYGTWQVLLGLK
AVGFDMKAPMIIKAVQWLKGCQHQDGSWGETCATYNDPSLAGQGEATPSQTAWAILGLLA
AGEENSDAVRKGISYLVNTQDSGGDWAEYFFTGTGFPKVFYLKYHYYRVYFPLMALSRYC
RALGYAFKQNTY
>A0A3N5KHE2|squalene-hopene cyclase|EC 5.4.99.17|Zetaproteobacteria bacterium|TrEMBL
MNPRVLRAPRPQDVSQAAALDLALQHGTEALLGRQDPAGFWVHELEADATITSEYLLLRR
WLGIADPVQEAKAARHLLSLQLPDGGWPIYANGPANVSATVKAYFALKMTGMSPTHPALA
RACGRVRDLGGITRVNVFTRILLALFGEMDWKGVPCMPVEIMLVPRWFYFNLYEISYWSR
TVLVPLLIIFAHRPVRPAPDHAHLDELYLVPRAEADLSFPRDAEAFTWRNVFLFVDRCLR
LHDRLVRQPFRQRAIRMAERWMLERMQGPGGLGGIFPAMANAVIALTCLGYDLESPEVVR
GLAAIDALCIDEPETFRVQPCLSPIWDTALTVSTLVEAGLAPDHPALVRAGLWLLDRQTR
AGGDWRLKLPDVQPGGWAFQFENEYYPDVDDSAVVLMSLRKIRLPDEEAKTRAIARGLNW
VLALQGKDGGWGAYDKDNDRVIFNKIPFADHGALMDPSTEDLAGRVLEALGFLGFRQDEP
AASRASAFVRARQYPDGAWYGRWGVNYLYGTWSVLAGLSSIGEDMSQPYIRKAVAWLLGR
QNPDGGWGESCFSYDDPRTAGMGNSTASQTAWALLGLLHAGEAAHPAVARGVQFLLSRQR
PDGFWDEAEFTGTGFPRVFYLRYHGYRAYFPLWALALYRHCAETGDRHVP
>A0A6P0UUT3|squalene-hopene cyclase|EC 5.4.99.17|Symploca sp. SIO1C2|TrEMBL
MQTQDSITTESTESIAEAIAKTQNYLLNLQYPEGYWWAELESNVTITSEVVLLHKIWGTD
QARPLHKVEAYLRSQQREHGGWELYYGDGGDLSTSVEAYMALRLLGVPATDPALLKAKKL
ILERGGISKTRIFTKFHLALIGCYDWRGVPSIPPWVMLLPEQFLFSIYEMSSWARGSTVP
LLIVFDHKPVYQTNPAITLDELYTEGASNVRFELPRNGDWTDLFVTLDDTFKLAEDLDFV
PFRQEGLEAAERWVLERQEVTGDWGGIIPAMLNSLLALRSLDYDVTDSVVVRGLEAVDNF
AIETAETYTIQPCISPVWDTAWVIRALVDSGIAPDHPAVVQAGEWLLSKQILGYGDWAVK
NPQGKPGGWAFEFENRFYPDLDDSAVVVMALDAVQLPQEDHKRTAIARAVAWMASMQCQE
GGWAAFDINNDADWLNYLPYADLKAMIDPNTADVTARVLEMLGSCNLSIEQGKLERSLTY
LLEEQEDDGSWFGRWGVNYIYGTSGALSALSVITPEKHRFSIEKGANWLVGCQNTDGGWG
ETCRSYDDPKLKGQGDSTASQTAWALIGLMAAGEAIGNWATEAIERGINYLVTTQLPDGS
WQEDYFTGTGFPSHFYLKYHFYQQYFPLIALGRYLK
>A0A7M2B9A6|squalene-hopene cyclase|EC 5.4.99.17|Brevibacterium sp. JNUCC-42|TrEMBL
MKEIIELEMKRIIHLLQKAQSADGAWRYCLESGPLTDAYMIILLRTLMIDDEELIRSLAD
RITIRQEKNGAWKLFHDEEEGNLSATIEAYYALLFSGHSRKTDEHMQLAKKFILTKGGIS
EASMLTKILLALTGQYPWSGYFQIPVEIILLPHWFPINFFDFVGYARVHIAPILVVADRK
FVIKTKRTPDISDLRKNDLPTALGNHPYLTNQRSHEYRALLNTILDGFKNLPYLPSQIHN
MALRQAERFILERIEPDGTLYSYFTSTFLMIFALLSLGYSANHPVITRAISGLKAMTCLT
NGHLHIQIATSTVWNTALLAHAMQGTGVSASDPTVQNACRYLLSRQHHKYGDWMMKNPFV
LPGGWGFSDINTINPDVDDTTAALRAISKLRETDPTFHHSWDRGLNWLLSMQNADGGWPA
FEKNTGKRILNWLPFDFDAADAVSTDPSTADLTGRTLEFLGNNAGFTIGHPQIQRGVKWL
LRNQEANGSWYGRWGISYIYGTWAAATGLMAVGVSSEHPAIQKAVQWLLKIQNEDGGWGE
SCKSDIVKAYVSLGASTPSQTAWGVDALISVFQKPIPAIERGIQFLINSEKNMDWTLSYP
TGAGLPGGFYFHYHSYRYIWPLLALGNYKKKY
>A0A844GY07|squalene-hopene cyclase|EC 5.4.99.17|Cyanobacterium aponinum 0216|TrEMBL
MTAQLTNPNKVEHSKVKSGIKQAQDYLFSLQEKDGHWCAYLESNVTLTAEAVLLYKIWGI
DSHKPLHKIEHYLRSQQREHGGWELYYGDGGDLSTSVEAYMALRLLGVAQEDEALTKAKR
FILSKGGISKSRIFTKFHLAIIGCYDWRGVPSIPPWIMLLPQNPIFTIYEMSSWARSSTV
PLLIVFDQKPVFKIEPKINLDELYSEGKENVKYELPRSGDWTDIFVQLDNLFKFAEDINF
VPFKEESIRAAQKWIIEREEATGDWGGIIPAMLNSLLAFKTLNYHVNDPMVARGLEAVEN
FALETHDDYLVQACVSPVWDTAWCLRALVESGVAPNHPALIKGGEWLLDKQILDYGDWVV
KNPHGKPGGWAFEYENRFYPDMDDSSVVIMTLHQLELPREDLKKEAILRCLRWIETMQCH
NYGWAAFDINNDANWLNLLPYADLKAMIDPATADITARVLEMVGSCDLPMSSSKVQKAIA
FLLHQQENDGSWFGRWGVNYIYGTSGALSALAVIAPQTSQEAMKKGINWLINCQNPDGGW
GETCDSYKNPALKGKGNSTASQTAWALIGLLDAGKALGKFEQDSINKGINYLLSSQTETG
TWEEKEFTGTGFPQHFYINYHLYRHYFPLIALGRFENFLV
>A0A3S0PZ65|squalene-hopene cyclase|EC 5.4.99.17|Dyella dinghuensis|TrEMBL
MNSTTPLTAPTTDDLFQPSQTSGLDQAIERGRVTLLEHQHKDGHWCFELESDCTITAEYI
LMMHFMDEIDDVLQEKMARYLRATQATQTHGGWSQYYGGAIDLSCTIKAYFALKAAGEDP
DAEHMRIAREAVLSHGGAAKANVFTRILLALFQQVPWRATPYVPVEIMLFPRWAPFHIEK
ISYWARTTLVPLTILCSLKAKAANPRNINIRELFVTPPEEERHYFVRGGLLNRSFLALDK
VGRFIDRFMPKSIRKRAVSKAESWFRERLNGEDGIGAIFPPMVNSYEAMALLGYPKDHPA
RQTCLRSIQNLVVHRDDGSAYCQPCVSPVWDTVWSALTLMHTSDDATTQSAIAKSVDWLR
SKQEMELKGDWAARAPDAPPGGWAFQYNNAYYPDIDDTAVAAALLHIQDRRNGESGRHRF
NTDRAADWMIALQSKNGGFAAFDADNTHYYLNAIPFADHGALLDPPTEDVSGRVAACLGV
LARPQDRESLRRCVDYLRSTQLEDGSWWGRWGSNYIYGTWSVLGGLALAGEDPQQPYIRK
SIEWLCSRQHADGGWGETNDSYIEPALRGTNHNVSTPQSTAWALLAQMAMGEVHSDSVKR
GIAFLLADQQATGLWYHPSHNAPGFPRVYYLKYHGYTAYFPLWALSRYRQLKKSSA
>A0A832MHG1|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MDGGSLSLPKGGSGNCNAGTAVETVVAASDFSPATMEAVDRTINDAIRWLAKEQNDEGFW
VGILESNSCMEAQWILAMHFLEIKDDPKYQGIIKAILREQRPDGSWEVYHEAPDGDINTT
VECYAALRCAGFKPDEEPLKKARQWILSHGGLKKIRNFTKFWLALIGEWPWEHTPNVPPE
IIFVPVWAPFNIYWFASWARATIVPLSILSARRPVRPLPQDRRLDELFPEGRENFDFSMP
RRLSGFWPTFFRVNEKLLHHYMSSPWKPGRETAIKLCLEWIIKHQDPDGAWGGIQPPWIY
SLMALYTEGYPVDHPVMFKGMDAWNHHWSYRRGDAIYIHASESPIWDTVLAIQGLLDCGE
TFETFPGLEKALDWLLKKQIFVKGDWAMTVKGVECGGWAFERANRLYPDIDDTAVAMIVL
ARLRKIAPKHFIPRIDYALKRAEVWVRAMQSSNGGWGAFDKDNNKWFLTLIPFCDFGEVL
DPPSADLTGHKLEALGCLGYTMDDPAVKRAVEYTMSEQEPDGSWFGRWGVNHLYGTALVL
PGLRAVGFNMKDPRIQKAAEWIANHQSKDGGWGESCASYMDDSFRGNGPRTPTQTAWALI
GLLAVGDHKYDDVIRRGIEWLIRHQKDGTWHESYYVGCGFPGYGIGERIRLKKNTLLLAQ
GRELSRGFMINYNMYRHYFPLQALGRARLHFQNKKSYLDR
>A0A536LM24|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MMQPTAFGASTSMRPALDEAIRRTQDYFLRTQRADGYWVGELETNVCMAAEYLLLTHFLG
IADDERWRKVVTYLKGRQSADGTWTIYFGGPPDLNATVEAYFALKLAGASPDDPYMRRAR
EFVLSAGGIPRVRVFTKIWLALFGQWDWRGVPALPPELMFLPRWFPLNIYDFASWARATI
VPMLIILTERPVCPIPENARIDELYPRGRKQTPYSLPKPKNRLSWNGFFDAADSVLRSYD
RVAISPLREAAYRVAERWILARQEADGSWAGIQPPWVYSLIALKLRAYSLDHPAMNKGIE
GFEGAWSIEDGEIFNPQACLSPVWDTALAMIALLDSGLPDGHPALVQAGRWLLREQVLTG
GDWQVRAKGLEPGGWSFEFENDIYPDTDDTAAVMIALARTELPEARKALALERGVHWLRG
MQSANGGWGAFDKDNTRRIVNEIPFCDFGEVIDPPSEDVTAHALEALSLFGEGRSSRPAL
RYLRREQRTDGSWFGRWGVNHIYGTGAVLPALAAAGEDMSRPYVRRAVRWLLARQNHNGG
WGESCSSYVDPSSIGRGPSTASQTAWALLGLLAAGGDSSDGIIAKAVQRGAGYLVETQEE
DGQWLEDEFTGTGFPGDFYIKYHLYRNYWPLMALGRSRLHLLS
>A0A2U3QG73|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Sulfobium mesophilum|TrEMBL
MDLISGEMSRILGRYFGFISTSPAEGENATFSAGRLDALNEEIARAAARTSGNYLGEQHP
DGYWWYELEANVTITSEYLMLLHFLGLYDRQRDELIARHILNNQRPDGTWAIHWGGEGDL
STTVEAYFALKLAGFDPDDPPLRKAREFILKNGGVESCRVFTRIFLALFGEFDWKAIPSI
PVEVNLMPSWFPMSIYRMSSWARCTFVPLSIVLDLRPVRPIPRGARIRELYKVPDKMPSL
SPKKLSTFSWKRFFFILDMVIKAAEDTPLRVFRNKAMGFTERWVRERQEPTGDWGGIQPA
MVNSILALSSLGHDVSHEPIRKGLEALERFTLEKEEELMLQSCISPVWDTALTSLALLHA
GLRKDHPQLIKACRWLASKQIFKKGDWSIKRPGLEPGGWAFEFENSWYPDVDDTAVVLML
LYRYADDGVIDRAKLDRGLSWILGMQGRDGGWGAFDVDNNMRILNQLPLGDLEAMIDPST
PDLTGRVLELLGQIGYGTNDRAVKKAIKFLRKTQEGDGSWWGRWGVNHIYGTCAVLCGLG
AVGESLKAPYVRKAVRWIKDNQNQDGGWGECCESYADPSLKCRGASTPSQTAWAMMALMA
AEQEIVEEVIRGVKYLLKRQKDDGTWDEEWFTGTGFPKYFMLRYHNYRNCFPLMALGKFC
QRSRSRGLGQ
>A0A068MR22|squalene-hopene cyclase|EC 5.4.99.17|Synechocystis sp. (strain PCC 6714)|TrEMBL
MVIAPSPSVPCPSTEEVRQAIAASRDFLLSEQYADGYWWSELESNVTITAEVVILHKIWG
TASQRPLEKAKNYLLRQQREHGGWELYYSDGGELSTSVEAYTALRILGVPATDPALIKAK
NFIVGRGGISKSRIFTKMHLALIGCYDWRGTPSIPPWVMLLPNNFFFNIYEMSSWARSST
VPLMIVCDQKPVYNIAQGLRVDELYTEGVENVQYKLPESGTIWDIFIGLDSLFKLQEQAK
VVPFREQGLALAEKWILERQEVSGDWGGIIPAMLNSLLALKVLGYDVNDPYVQRGLAAID
NFAVETEDTYSIQACVSPVWDTAWVVRALAEADLGKDHPALVKAGQWLLDKQILTYGDWQ
IKNPQGKPGAWAFEFDNNFYPDIDDTCVVMMALQGITLPDEERKQGAIDKALQWVATMQC
KTGGWAAFDIDNDQDWLNQLPYGDLKAMIDPSTADITARVIEMLGACGLTMDRQRVARGL
AYLLQEQEQDGSWFGRWGVNYLYGTSGALSALAIYDAQRFIPQIKMAIAWVLSCQNADGG
WGETCESYKNKQLKGKGSSTASQTAWALIGLLDAAKELPDLQKDNDLMTAIERGVAFLIA
GQTTKGTWEEAEFTGTGFPCHFYIRYHYYRQYFPLIALARYSHLRAF
>A0A454WEN9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. WAC02707|TrEMBL
MTATTDGSTGATLRPLAAAASENEITTPDTAAGVPEAAARATPRATDFLLSRQDAQGWWK
GDLETNVTMDAEDLLLRQFLGILDEETTRAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDAPDAPHMARASEWIRSRGGIAASRVFTRIWLALFGWWKWDDLPELPPEII
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAVPNPPRPLAPAA
SWDGAFQRIDKALHAYRRIAPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHP
QLVKAADWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHH
DPERVEQAIGRGVRWNLGMQSKNGAWGAFDVDNTSSFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAVEGLTHDPRTRRGIQWLLAEQEADGSWFGRWGVNYVYGTGSVVPALIAAGVPAS
HPAVRRAVAWLESVQNDDGGWGEDLRSYRYVREWSGRGASTASQTAWALMALLAAGERES
KAVERGIAWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFA
QKSGAARPATETSAAEVKGS
>A0A6L8N4U1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5473|TrEMBL
MTATTDGSGGPVRARAAADSETASAPAPAGRPGERTAGDERTGSARRAVNRAVDHLLARQ
DAEGWWKGDLETNVTMDAEDLLLRQFLGIGDRAVTEASARFIRGRQRADGTWATFYGGPG
ELSATVEAYVALRLAGDLPGDPHMARAAAWVREQGGIAATRVFTRIWLALFGWWRWEDLP
VVPPELIFLPKWFPLNIYDFGCWARQTIVPLTVVSARRPVRPAPFALDELHTDPLLPNPP
RPLAPANSWEGFFQRADRALHRYHRVAPRRVRESAIAAASRWIVERQENDGCWGGIQPPA
VYSLIALHLLGYDLGHPVMRAGIESLDRFAIWEKTETGAPVRMIEACQSPVWDTCLATVA
LADAGLAPDHPALVRAADWMLGEEIVRPGDWAVRRPGLAPGGWAFEFHNDNYPDIDDTAE
VVLALRRVAHPDPARVDAAVARAGRWTLGMQSRDGGWGAFDADNTSPFPNRLPFCDFGEV
IDPPSADVTAHVLEMLAYEGRAHTPRARRAVDWLLAHQEPGGAWFGRWGVNYVYGTGSVV
PALVAAGIPAAHPALRRAVDWLRSVQNPDGGWGEDLRSYDHGAWAGQGSSTPSQTAWALL
ALLAAGERDSESAERGVRWLVEAQRDDGGWDEPYFTGTGFPWDFSINYHLYRQVFPLTAL
GRYVHGEPPVGGVPRAGTPRAVAVTARKGS
>A0A7K2HK36|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4936|TrEMBL
MTATTDGSTGAVNPRAASASQPTDTTIAADDVLAAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPATVEAAGRFIRGEQLGDGTWATFHGGPGELSTTIEAY
VALRLAGDRPDDPHMARAAGWIREQGGVAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPRNPNPPRRPAPAASW
DGVFHRLDKALHVYHRIAPRKLRRTAMNAAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVSPDHPAL
VKAADWMLGEEIVRPGDWSVRRPRLNPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDR
ARVEAAIRRGVRWNIGMQSRNGAWGAFDADNTSGFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGRSGHRVTRRGIEWLLAEQEASGAWFGRWGVNYVYGTGSVVPALVAAGLPPTHP
AIRRAVGWLESVQNDDGGWGEDLRSYREEKWIGHGASTPSQTAWALLALLAAGRRDSGAV
QRGVSWLGETQRPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGEPFADRT
ATRKEA
>G6FPH9|squalene-hopene cyclase|EC 5.4.99.17|Fischerella thermalis JSC-11|TrEMBL
MQTQDRVTASKLPDAIAASQNYLLSIQNPQGYWWAELESNVTITAEVVLLHKIWGTDKSR
PLEKVEAYLRSQQREHGGWELFYDDGGELSTSVEAYMALRLLGVPPTDSAMLKARKFILE
RGGISRTRVFTKLHLALIGCYSWQGIPSLPPWVMLLPENFFFNIYEMSSWARSSTVPLLI
VCDRKPVFAIDPAINLNELYAEGIEQVKYELPRSGNWTDIFLTLDSGFKLAENLNLVPFR
TEGIKAAEKWILERQEATGDWGGIIPAMLNSLLALRCLDYDAADPIVERGLQAVDNFAIE
TADTYRVQPCVSPVWDTAWAIRALVDSGLAPDHPAVVRSAEWLLNKQILDYGDWAVKNRQ
GKPGAWAFEFDNRFYPDVDDTAVVVMALNQVKLPNQKLKHQAMRRAVEWVASMQCKAGGW
AAFDLDNDQDWLNLIPYGDLKAMIDPNTADVTARVLEMLGSCHLSIDRYNQQRAIQYLLN
EQEPEGCWFGRWGVNYIYGTSGALAALSLVAPQTHRYNIEQGAAWLISCQNSDGGWGETC
RSYDDPRLKGKGRSTASQTAWALIGLMAAGRATGNFAKPAIERGIDYLLVTQLPNGSWDE
ADFTGTGFPSHFYLKYHLYQQYFPLIALGQYQKLFA
>A0A544YY28|squalene-hopene cyclase|EC 5.4.99.17|Microbispora hainanensis|TrEMBL
MTGVTTGVTTGAAAAAAAGVTAGVATSAARAATALKAARDHLLGLQSPEGWWKGELQTNV
TMDAEDLLLREFLGVRTAEETAEAARWIRSQQRADGTLSGTWANFHEGPADLSTTIEAYV
ALRLAGDPPSAPHMRAAAAYVRGAGGIESARVFTRIWLAMFGQWRWEDLPVIPPEIMFLP
PWCPLNVYDWACWARQTIVPLTIVTAHRPVRPLPFGLPELRTGRPAPRPPRTGWDAAFAA
LDRALHRYERHPVAGLRRAALRRAVEWVVARQEADGSWGGIQPPWVYSLIALHLSGYGIG
HPVMRAGLAGLDRFTIREDGTRRLEACQSPVWDTALAMTALLDAGLPPDHAALSRAGEWL
LREEIRGPGDWAVRRPGLAPGGWAFEFDNDGYPDVDDTAEVILALRRLGRPDARPALERG
LRWTAGMACRDGGFAAFDADNTRELCLRLPFCDFGAVIDPPSADVTAHVVEALAAEGMAR
SPVVRRAVVWLLRAQEPDGSWFGRWGANHVYGTGAVLPALAAAGVRPEAPCVRRAVAWLE
AHQHPCGGWGEDLRSYRDPAWIGRGEPTASQTAWALIGLLAAGERGPSVDRGVAWLADSQ
RPDGTWDEPYYTGTGFPGDFAINYHLYRLVFPVSALGRYLRLHETAGPEATPCPI
>A0A7S9D1V8|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium genosp. B|TrEMBL
MDSVNATSREALESKVLESSIASATQGVLGFQQSDGHWVFELEADATIPAEYILLRHHLG
EPVDAQLEAKIGNYLRRIQGAHGGWPLVHDGPLDMSASVKAYFALKMIGDSVDAPHMVRA
REAIHAHGGAVNSNVFTRFTLAMFGVLTWRAVPVLPVEITLLPFWFPFHINKISYWARTT
MVPLLVLAALKPRAKNPKGVGIDELFLGDPRSIGMTAKAPHQSMAWFLLFRALDTILRVV
EPMFPKRLRQRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKDENYPPRATTR
RGLDKLLVIGDDEAYCQPCVSPIWDTTLTAHALLEAGGDKAVPAAKQGLDWLIPKQELEV
KGDWAVKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGTAGYDAAIDRAREW
IEGMQSDDGGWAAFDVNNFEYYLNNIPFSDHGALLDPPTEDVTARCISMLGQLGETEKTS
KHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGIRHDDPMMRKAANWLAS
IQNKDGGWGEDAVSYRLDYKGWEAAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIAT
QNQKGLWDESRYTATGFPRVFYLRYHGYAKFFPLWALARYRNLRSTNSRVVGVGM
>A0A7L5XCN5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces albidoflavus|TrEMBL
MTATTNGPAGAAPSRPAPARTTAATTDTAALDGAAVEAAAERARARAVDHLLGLQSPEGW
WKGDLDTNVTMDAEDLLLRQFLGIRDEATTRSAALFIRGEQREDGTWATFHGGPPDLSTT
VEAYVALRLAGDSPDAPHMTRAAHWVRSQGGIAEARVFTRIWLALFGWWPWDRLPELPPE
LIFLPPWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPADPAPRARFAP
LASWNGAFQRLDRALHAYRKVAPRALRRAAMATAGRWIVERQENDGCWGGIQPPAVYSMI
ALHLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALADAGVPAD
HPQLVRAADWMLDEQIERPGDWSVRRPHLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVR
HPDTARMERAISLGVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDPPSADVT
AHVVEMLAAEGLAADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALVDAGLP
TTHPAIRRAVAWLESVQNDDGGWGEDLRSYREQGRMARGASTASQTGWALMALLAAGERE
SRAARRGVTFLAETQHEDGSWEEPYYTGTGFPWDFSINYHLYRQVFPLTALGRYTRGAAP
EGA
>A0A5B2TDP3|squalene-hopene cyclase|EC 5.4.99.17|Roseomonas oryzae|TrEMBL
MQGNIRQAPAASPLEEVEAALRRAAEALRRQQRPDGHWVFELEADATIPAEYVLLRHYLA
EPEDSALEAKIGAYLRRIQGAHGGWPLFHGGAFDLSASVKAYFCLKMIGDDPQAPHMARA
RAAILAAGGARRANVFTRILLAQFGELSWRYVPTIPVEMILAPRWLPVHLSKMSYWARTV
LVPLLVLQALRVRARNPRGVRIPELFCAAARPPRRHGHQHPGWAMFFNGLDRVLKLGEPF
WPRALRRRAIARCVDFVTERLNGEDGLGAIYPAMANSVMMFDALGYPPDHPDRAIARRSI
EKLLVVADDEAYCQPCVSPVWDTALVSHALMEAGGQADMAAARRGLEWLRPLQELEVKGD
WAEWRPDVRPGGWAFQYRNAHYPDLDDTAVVVMAMDRARDACDAGYDAAIDRAVEWTTGL
QSRDGGWGAFDADNHHQYLNNIPFADHGALLDPPTADVSARCISMLAQLGEAPDSSRMRA
ALGFLLREQLADGSWFGRWGVNYIYGTWSALCALNAVGTEEVAPAIRRGAEWLLAIQNAD
GGWGEACDSYKLDYRSYEAAASTASQTAWALLGLMAAGEVDHPAVARGIAWLQAQQDDDG
LWSQEAHTGGGFPRVFYLRYHGYPKFFPLWALARYRNLKRSNARRVPHGM
>A0A6L3APN6|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Jettenia sp. AMX1|TrEMBL
MRNFLVNLFERLETGIHKSNGNGNGKHLISELPKHKLIFENTFPGVPASTLSTKNPLDSA
IQRSQQYILREQNKTDGHWVGILEADTTLTSDYIMLMHFLAKVDHEKQKKAARLILDHQL
PDGGWNIYYGGPSEISASVKAYFALKLAGYSANESVMQKARKCILDMGGIMRANCFTKIY
LAMFGQVDWQAVPAVPAEMILFPPGFYFSIYEMSYWSRCIVVPLSIAIAKKPHIPVDDDL
LSELYLIPRNKVVYRIKRNQSGWCWHNFFIDADSIFRRYEQQPIKFIRQIALKKAEKWML
DHMDNSGGLGAIWPGIINSIFAMKCLNYPEDHPALLSQLKEVENLIIYETDRLYLQPCVS
PVWDTAWAIIALHESGIPNTHPSLQKAGRWLLSKEVRNFGDWTLKCKVEEPSGWYFQYAN
EFYPDTDDSAAVLMALQRVSLPESAHKERTFLRGLKWLQAMQCDDGGWGAFDRNNNKAIL
NHIPFADFNALLDPSTSDVTGRCLEFLGRVGFSNTYTNIRSAIEFLQKEQEKDGSWFGRW
GANYIYGTWSVLSGLSTAGEDMDKPYIKKAVEWLRKSQNSDGGWGETIKSYDDPSLKAIG
KSTPSQTAWALLAFFAVNEIKSDAVERGIKFLLNGQKEDGSWDETEFTATGFPKVFYLKY
HMYRNYFPLLALSRYRNLIQKL
>A0A6C6YHS7|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia mallei (strain NCTC 10247)|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANAMRVTVGM
>A0A6P0YSV2|squalene-hopene cyclase|EC 5.4.99.17|Merismopedia sp. SIO2A8|TrEMBL
MPISEQNETAPTQGTNHGHKKHETSGEVLRNAIASSQAYLLSQQYQDGYWWAELESNVTI
TAEVVLLHKIWGTDGSRPLHKVETYLRREQRDHGGWELFYDDGGNLSTSVEAYMAMRLLG
VPADDPAMVKARDFILNQGGITQCRVFTKFHLALLGCYDWRGVPSIPPWIMLLPQSFPIY
EMSSWARGSTVPLLIVFDQKPVYSMDSPITLDELYVEAPDQMDYSFSEKGDWTDIFLALD
GAFKVAEELNLVPFREEGLRAAEQWVLERQEETGDWGGIIPAMLNSMLALRCLDYDAYDP
IAARGFAAIDRFAVETDETYHIQPCISPVWDTAWCVRALRDSGFDPEHPALVKAGQWLLD
RQILDYGDWLVKNPQGRPGGWAFEFVNRWYPDVDDSAVVVMALSQLTFPDDAQEKLKQGA
IARTVDWIATMQCKPGGWGAFDIDNDQDWLNALPYADLKAMIDPNTADVTARVIEMVGYL
SEGNGNSSSNGGDNGDSHTSISPGLCKQKPYRNVPFLLPKVEYQKPYRLERSLRYLLNEQ
ESDGAWFGRWGVNYIYGTSGAISALALVNPQDHQDAIVKGADWLVQCQNSDGGWGETCYS
YHDPSLRGQGDSTASQTAWALIGLIAAADVTEHAAINAIEKGVQYLLQTQLPDGRWDEDY
FTGTGFPCHFYLKYHFYQQYFPLIALGRYQSSFG
>A0A5C8JB79|squalene-hopene cyclase|EC 5.4.99.17|Nonomuraea sp. C10|TrEMBL
MSTADTLRSTRLALDAARDHLIGLRSPQGWWKGELQTNVTMDAEDLLLREFLGIRAKDDT
AEAAHWIRSEQRADGTWATFHGGPPDLSTTVEAYTALRLAGDPVEAAHMRAARSFVRESG
GIESARVFTRIWLAMFGQWPWERLPVLPPELMFLPSWFPLNVYDWACWARQTIVPLTIVS
ARRPVRPLPFDLAELRTGRPVPRRGGLGWDGFFHGLDRLLVRYERRPVRGLREAAIRRAA
EWIVARQEADGSWGGIQPPWVYSLIALNLSGYDLDHPIMRRGLRGLDRFTIRDERGRRLE
ACQSPVWDTALAVNALLDAGVSHDHPAVAEAVDWLLEEEIRGPGDWAVRRPRLAPGGWAF
EFDNDLYPDIDDTAEVVLALSRTGRPDARPAIGRAVRWMTGMASRDGGFAAFDADNTRTL
CTKLPFCDFGAVIDPPSADVTAHVVEALAQESAPGSPELRRAVLWLLKAQEPDGSWFGRW
GANHVYGTGAVVPALVAAGVRRDAACVRRAVAWLESHRNQDGGWGEDLRSYTDPAWIGRG
ASTPSQTAWALMALLAAGERSPVVDAGVRWLVEHQRPDGTWDEPHFTGTGFPGDFSINYH
LYRLVFPVNALGRYLRACGQAP
>E8R5V6|squalene-hopene cyclase|EC 5.4.99.17|Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B)|TrEMBL
MIVTAQDGRGLAAPVSEQAAADSALAARRAAAWLLAQRKTDGHWVGELEGDTILETEWVL
LKAFLGELDDPEVVAACRSVRRDARPEGGWAIHPGGPFEISASVKAYFALKLVGVSPDEP
DMVRARELILQHGGLDACNSFTRFYLALLGQIPYDDCPAVPPELVWLPSWVPFGLAAMSS
WTRTLVVPLAILSSLKPCRPVPDALRIDELKNPHFVPDWRKPAGLFTWRGFFLGVDRLLK
AFDRIKPGVWRRAAVRSCHQWMLDHFEDSDGLGAIFPPMIYTVVVLETLGYDRNDRLFEW
AVRQLDDLKVRDEENGLLWLQPCLSPVWDTAIATIALADVRDAQAENNPAARAELETALT
TASRWLVAREIRRKGDWAIRRRFRHIEPSGWAFEYLNDHYADIDDTAMVLMALDRAGLRD
DPTVKPAIERALNWLLALQGRDGAWAAFDADIDNQVLTQVPFADHNAMLDPGCADITARV
VEMLGQLGFASSHPSIQRALEFIWSRQEPEGWWEGRWGVNAIYGTWQVLQGLAALGWPMS
DPRLVKAADWLETIQQADGGFGESCRSYEDRSWIGQGPPTPSQTAWGLLGLIAAGRADSP
AAHRAAAWLRDRQTSHGDWPEDQFTGTGFPKVFYLKYHLYRVSFPIMALARHARALTRRP
S
>A0A535B586|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MIANLTGPHRFELERAIQNAANALLGLQHPDGDWCFELEADCTIPAEYILMMHYMGESDE
KLERKLVSYLRARQGRDGGWPLFYGGRSEISCSVKAYYALKLAGDDPELPHMARARETIL
RLGGASRANVFTRITLAVFAQIPWRAVPFLPVEAMLLPRWFPFHPFKVSYWSRTVMVPLF
VLYTFKARARNPKQVSIRELFITDPWHETRYFPTRSALNRALLMLDRLGLKLYPWIPERL
RWRAIKKAEAWILQRLNGEGGLGAIFPAMVNAYEALDLLGYPANHPLRVQERRAIENLLV
IDEQSAYCQPCVSPVWDTAWACIALQQVGGERSQAVVRKAFHWLAERQLLDDPQDWRFNR
PRVRGGGWPFQFKNSHYPDLDDTAAVAYAMHKSGEGTFTHAVERAAEWICGMQSRNGGFA
SFDADNDHTYLNEIPFADHGALLDPPTEDVSGRCVMFLAQLAPKYKSVEKNCLDYLFRSQ
EPDGSWFGRWGTNYIYGTWSVLMGLEEAGIGREHEPVRRAAAWLKNVQRADGGWGEGCDT
YFDPSKRGQGERSTSFHTAWAVLGLMSAGEVHSDSVRRGVEFLLRTQKLDGFWSDPDFNA
PGFPRVFYLKYHGYDKYFPLLALARYRNLAAER
>A0A072NJT2|squalene-hopene cyclase|EC 5.4.99.17|Schinkia azotoformans MEV2011|TrEMBL
MNEKITTRLNELIEKVRNDQSPEGYWNYTFETGISTDCYMIILLRSLEIDDENLIKELSE
RILRKQQENGAWKLFHDEPNGNLSDTIGAYYALLYSGYYSKNDPRLRLARQFIKTNGGID
KSHMLTKIMLALTGQYKWPVFFPIPIEMILLPVSFPINFYSFSVYGRVNLAPIMILANKK
FSIKTSKTPDLKDLFIHREEFEHGHSFRFRESEEWRSLSSLINQGIKSLIGLPSHVHQLA
TEYTKQYMLSRIEPDGTLLSYFSSTFLMIFALLSLGISKSDPIIVNAVKALKSMISRDIN
GLPHMQFTTANVWNTSLLTYALQESGILSDDIVVKKANIYLLKKQHYKYGDWVIHNPSAL
PGGWGFSESNTIHPDVDDTTASLRSIARNVRKDWRCRQAWDRGIQWVLSMQNDDGGWPAF
EKNTNSKIVHLFPVEKAEYFLSDPSCADLTGRTLEFLGTYTNLSKTHPSIKRGVDWLLKN
QERNGSWYGRWGICYIYGTWGAVTGLRAVGILPTDPMISKAVKWLKEIQNSDGGWGESCQ
SDLNKKYIPLNASTLTHTAWAVDALIAASDKPTRSIQRGVDYLLENIHKEDWTTTYPKGA
GMAGDFYIHYHSYRSIFPILTLAHYRKKFS
>A0A6L7JLH9|squalene-hopene cyclase|EC 5.4.99.17|Acidimicrobiia bacterium|TrEMBL
MSGRVYRREGLLNAAVESLSKAVDRLLSLQASQGWWKGELETNVCIEAEDLFLREFLGIA
DAEITRQTANWIRHTQRADGTWPTFYQGPSDLSVTVEAYWALRYAGDPADADHMIKAAAY
IRSEGGLERSRVFTRIWMALFGLWSWDDLPALPPEVILLPKQVPLNIYDFACWARQTVVA
LTVVGAHRPVRSMGINIDEIRTGVRSAEREPAPLASPARRFQQLDRLLHRYENRPYRRIR
NWALNRAEQWIIARQEADGCWGGIQPPWVYSLLALYLRGYSLQHPIMAQGLAGFDTWTII
ENDMRRLECCQSPVWDTCLSLVALADAGVACDHSKMVKGGSWLLSQEVQVVGDWAEQRPH
LSPGGWAFEFENSYYPDLDDTAEVALALRRIDLEDANAAQKALKRAVSWVQGMQCSDGGW
AAFDADNCSTLVAELPFCDFGEVIDPPSADVTAHIVEMLCELGKDVDGYGVDQEAIQRGV
RWLSDNQEADGSWYGRWGANYIYGTGAVVPALISAGVSSDDPLVVRACDWLESVQNSDGG
WGEDMRSYVDLQWRGRGESTPSQTAWALLCLIAAGRADTQAAHRGVGWLIECQRSDGDWD
EPWHTGTGFSGDFYIRYHLYRLVFPVMALGRWVRAMSVDK
>T2B0F9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHALLEANLALDKAIMQKAADWLVERQILDVIGDWGANARGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRVDPNRYSEAIERGAEWIIGMQSGNGGWGAFDKDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMLAQLGYGYEIEAVSRVVGYLKREQEHDGSWYGRWG
>T2AYN2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIFMEKAANWLVKRQILDVIGDWGANVHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDCYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGRWG
>T2AZN4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKIIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWFGRWG
>T2AZ65|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWYGSWG
>T2AYN4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDDPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAITLLSLADKKIYSKNIKDGINYIKSEQEEDGSW
>T2AZN8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAICSNALLDSGLPTDHPALVRAGKWIVSKQVTKRGDWQVKNPKAEPGGWAFEFY
NELYPDTDDTAEILLFLNRVEILDNRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGKWGFNKQHPPVKRAIKFVKERQEVDGCWYGR
WG
>T2B026|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PVWDTALVSQALIEIEYKQHVSTEIETALNWLKEQQLNEEPGDWRIQKPELSGGGWAFQY
SNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYLN
EIPSADHGALLDPPTVDVTGRAITLLSLADKKIYAKNIKDGADYIKSEQEENGSWYGRWG
>T2AZU8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTALVSQALIETEYKQHVSTEIETALNLLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADRKIYEKNINDGVNYIKSEQEEDGSWFGRW
G
>T2AZB3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLNGLSLLESGLTLNDNAIQKACKWLEKKQILEMKGDWIVNNKNLLPGGWSFQY
ENDFYPDVDDTAVVGMFLDRAGYQNKKRLERACNWIAGMQSKNGGWGSFDKDNTDHYLSN
IPFADHGALLDPPTADVSARCVSMLSQINKKNYKNEIQKGIKFLK
>T2AZU1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELIGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSQGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAITLLSLADKKIYEKNIKDGVDYIKSEQEEDGSWFGRW
G
>T2AYH6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAAHAVLETLGGNTLLLNKSCDWLSKLQIKEHTGDWGWRRKGLRPGGWAFQYN
NKFYPDVDDTAVVGMALHRQNPEKYADTISRAEEWIIGMQSSNGGWAAFDADNEYYLLEN
LPFADHRALLDPPTADVTARCISFLTQIGTSNNHPISRGPEFLKRNQEEDGSWFGRWG
>T2B0E9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAAHAVLETLGGNTLLLNKSCDWLSKLQIKEHTGDWGWRRKGLRPGGWAFQYN
NKFYPDVDDTAVVGMALHRQNPEKYADTISRAEEWIIGMQSSNGGWAAFDADNEYYLLEN
LPFADHRALLDPPTADVTARCISFLTQIGTSNNHPISRGLEFLKRNQEEDGSWYGSWG
>T2AZX2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELIGGGWAFQ
YSNYYYPDLDDTSMVAWAMYRTNDKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAITLLSLADRKIYDKNIKDGVDYI
>T2AZG3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
VDTAITEICLHAGGVSADSKQLRKTTDWILDREIRFHGDWKFKNPTDAEPSGWAFEHENK
WNPDVDDTAMVLMALRRVPGSDRRRRDIAVERGLRWMLTFQCKDGGWGAFDKDCTKDILN
KVPFADHNAMLDPECADITARILEFLGQEGYSTDNQQVKKAIQFLHDNQEEDGSWFGSWG
>T2AYB8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTAICSNALLDSGLPTDHPALVRAGKWIVSKQVTKRGDWQVKNPKAEPGGWAFEFY
NELYPDTDDTAEILLFLNRVEILDNRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGKWGFNKQHPQVKRAIKFVKERQEVDGCWYGR
WG
>T2AYR8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHALLEANLARDKAIMQKAGDWLVERQILDVIGDWGGNAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPNRYSEAIERGAEWIIGMQGGNGGWGAFDKDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMLAQLGYGYEIESVSRVVGHLKREQEHDGSWYGRWG
>T2AZG6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGLAIHSLAEANGESQTNELNRAAAWLAEKQILDVNGDWSHKRPGLRPGGWPFQY
TNDYYPDVDDTAVVALALDKMDSKKFRVNIERAAEWIVGMQGVNGGWGSFDADNTYGYLN
HIPFADHGALLDPPTADVTARCVGMLAQISVERYSNTIKRGIAYLYADQENDGSWFGRWG
>T2AYZ5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAITLLSLADKKIYEKNIKDGINYIKSEQEEDGSWFGRW
G
>T2AZF8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLATHAMLEANLSSGPRILENDSTSKACKWLENLQIKDCAGGWAVWRPNLRPGG
WAFQYRNDFYPDIDDTAVVAMALHRSENKIYEPTLLRAAEWIIGMQSKNGGWAAFDADNE
YYLLENMPFADHGALLDPPSVDVSARCISFLTQLGYDQTNGTIKRGIEYLKKNQEEDGSW
YGRWG
>A0A4Y9N8I2|squalene-hopene cyclase|EC 5.4.99.17|Geodermatophilus sp. DF01_2|TrEMBL
MTRIPASDVPTPSTAPAAGAAEALERARNWLLDRQHPDGWWQGELESNVTMDAEDLLLRE
FLGVRTATQTRESAAWIRSRQRDDGSWATYPGGPGDLSTSVEAYVALRLAGDPPDSDSLR
RAREFVLASGGIENARVFTRFWLALFGQEPWSELPVLPPELVLLPRWAPLNVYGFACWAR
QTIVPLAVVGALRPSRSLGFDLAELRAGPRPAAPAASRTGRAFQRLDRLLHRYERHPLRP
LRRLALARAGRWILERQEADGSWGGIQPPWVYSLIALHLLGHPLDSPPVQAGLGLERFTV
RAGGMRRIEACQSPVWDTALAAIALTDAGLPPGAPALRRATDWLLGEEVRIRGDWAVRRP
RLAPGGWAFEFDNDLYPDVDDTAEVVVALSRTAAGSPAARAAVDRGTAWLVGMQSRDGGW
GAFDADNTSRLCRHLPFLDFGEVTDPPSADVTAHVVEMLAVTGSADSTAARRGVAWLLDV
QEPDGSWFGRWGVNHVYGTGAVVPALVAAGVDPGAPPVRRAVRWLETSQAADGGWGEDPR
SYADQAWRGRGTPTASQTAWALLALLAAGERGGVVDRGVRWLARTQRPDGSWEEPQATGT
GFPGDFYLTYHLYRQVFPLMALGRYLHREPGGAR
>A0A849V850|squalene-hopene cyclase|EC 5.4.99.17|Methyloglobulus sp|TrEMBL
MFTDANSATPSSSTQSSSTAIVFEDHQLDVAIHKAQDKLLSLQDKRGYWVFDLEADCTIP
AEYIMMMHYLDDIDEVLQAKIANFLRARQSADGSYPLFTHGQGDISCSVKVYYALKMSGD
SIDASHMVNLRRYILAQGGAAKANVFTRIALAIFQQLPWRGVPFIPPEIMLFPKWFPFHL
DKVSYWSRTVMVPLFILCTFKATAKNPNNVSILELFVTHPDEEQHYFPERTVLNKFFLGL
DKLGRIVEPFIPAKIHQKAIDKARDWIIERLNGEDGLGCIFPAMVNAYESLMLFGFPKDH
EYVATARKAIDKLLVIKEHEAFCQPCVSPVWDTGLTALALQEVDKVGNAESLNKAYDWLK
SVQLSDEPGDWRISKPDLAGGGWAFQYANPHYPDVDDTAVVGFAMADSNLSGLDESIHRA
THWIEGMQSKNGGYGAFDVDNTYYYLNEIPFADHGALLDPPTADVSARCAMLMARVIKDG
HESYRPALQRTINYLRSEQEKDGSWFGRWGTNYVYGTWSVLLGLEQTDLAKTDSMYVNAV
KYLKSVQREDGGWGEDNYSFHDTSYSGKYHFSTAFQTAWAVLGLMAAGEGHSPEVKAGID
FILRSQQADGVWDDPCFTAPGFPRVFYLKYHGYDKFFPLWALARYRNELKL
>A0A149SSY7|squalene-hopene cyclase|EC 5.4.99.17|Gluconobacter thailandicus|TrEMBL
MNAPILKGMSNSLAHTVSSACDWLIGQQKGDGHWVGSVESNASMEAEWCLALWFLGLEDH
PLRPRLGNALLEMQREDGSWGIYFGAGNGDINATVEAYAALRSLGYSEDYPALRKASTWI
AEKGGLKNIRVFTRYWLALIGEWPWEKTPNLPPEIIWFPDNFVFSIYNFAQWARATLAPL
AILSARRPSRPLRPQDRLDALFPEGRERFDYTLPKKEGRDAWSSFFRTTDKGLHWLQSKF
LKRNTVREAAVRHLLEWIIRHQDADGGWGGIQPPWVYGLMALHGEGYQFHHPVMAKALAA
LDDPGWRYDKGEASWIQATNSPVWDTMLALMALYDANAQERFTPEMDKGLGWLLDRQVRV
KGDWSIKLPDVEPGGWSFEYANDRYPDTDDTAVALIALSFCRHREEWKRKGVDEAIARAV
NWLIAMQSSCGGWGAFDKDNNKSLLSKIPFCDFGEALDPPSVDVTAHILEAFGLLGLSRE
LPAVQRALAYVRAEQDPQGPWFGRWGVNYLYGTGAVLPALAAIGEDMSQPYIGKACDWLI
SCQQDDGGWGESCASYMDISSIGRGTTTPSQTAWALMGLIAAARPQDYEAIAKGCRYLID
RQQADGSWTEEEFTGTGFPGYGVGQTIKLDDPALSKRLMQGAELSRAFMLRYDLYRQFFP
IMALARASRLPDTGTMIFSG
>A0A3R7IX76|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces xinghaiensis|TrEMBL
MTATTDGSSGPRPPALPAGGPPGPLPAPPTAPGGQSAGPHPDSGTPDPGPPAPGPRDTPA
AAERAAARAVRNLLGRQHDEGWWKGDLETNVTMDAEDLLLREFLGIGDRRTTEAAARFIR
SRQCPDGTWATFHGGPGDLSATIEAYVALRLAGDAPAAPHMAAASAWVREHGGIAASRVF
TRIWLALFGWWPWEQLPELPPEMIYLPKWFPLNIYDFGCWARQTIVPLTVVSALRPVRPA
PFPLGELHPDPAAPRRAAATATGWDRVFRRLDRLLHAYRRVAPPPLRRAALRACARWIVE
RQENDGCWGGIQPPAVYSVIALHLLGYDLDHPVLRAGLDSLDRFAVWQDAPGPGGGPSRM
VEACQSPVWDTCLATIALTDAGLPAGHPALVRAADWMLGEQVLRPGDWSVRRPGLPPGGW
AFEFHNDNYPDTDDTAEVVLALRRTAHPDPERVDRAVRRAVRWTLGMQSADGAWGAFDAD
NTSAFPNRLPFCDFGEVIDPPSADVTAHVVEMLAAEGLAGDPRVRRAVAWLLAEQEPSGA
WFGRWGVNHLYGTGSAVPALVAAGVPAEHPAIRRAVDWLNSVQNEDGGWGEDLRSYPDPE
WIARGESTASQTGWALLALLAAGEEDGKAVERGIGWLARTQREDGSWDEPQFTGTGFPWD
FSINYHLYRLVFPLTALGRYLTAVGRPPRTGPRDA
>V4L3Y9|squalene-hopene cyclase|EC 5.4.99.17|Desulfofustis sp. PB-SRB1|TrEMBL
MDATTLNNAIEQAIAWLMGAQHQDGYWVGNLQSNSCMEAEWVLAMYILGVLADPKYDGVV
KAILHDQRADGSWEIYYDAPAGDINATVESYAALRVAGVDKNSDPMIRAREWIFAHGGLG
GVRVFTKYWLALIGEWPWDRTPALPPEIFFIPRWAPFNIYKFATWARATMLPLSILTARR
PVHRLPDNLRMDELFPEGREHFNYRLPRKKRWISWEGFFLATDRILNRYVNAPLRPGRET
AIRLCREWIVAHQDGDGAWGGIQPPWIYSLMALHEEGYALHHPVLTSGLTAFDPPWSYER
DGRIYLQPSVSPIWDTVLVLLALLDCSVAHLQTVSVEKAVRYLLSQQVLVGGDWQVFVKD
TEPGGWAFEYENDKYPDVDDTAVAVIVLLRLEPLMADEGLKRAMREAVEKAVAWLIAMQN
DNGGWAAFDRDCTSAILTLIPFADFGELLDPPSVDVTGHVVEALALYGMTRDDEVMTRAC
RYMLDEQEPDGSWFGRWGVNYIYGTGAVLPALEAAGVDMSAEKIVAAGRWLVSRQNLDGG
WGESCASYMDEQFRGRGVSTASQTGWALMALIALDSDEFARPIKQGLEFLKKTQNQDGTW
DEPYFTGTGFPGYGVGERIDLTVKSDTMNQGSELSRGFMLNYNMYRHYFPLMAMGRARRY
LTAGVS
>A0A6I4ZBQ0|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
MQGAQAAAGSASGLDVCIDRSVRHLLSLQAEDGYWWAELESNATMAAEHLLLERFLGTTE
EEREQGIVRYLLGLQCEDGSWPVYWGGPGDVSISTEAYFALKLAGVDPEREEMKRAREFI
RSRGGVGATRIFTKLWLSLFGQFDWSALPAMPPESILMPVASPLNIYMFASWARATIVAI
LVVWAYRPVVPIPDYAHVDELYLDPADRRSIPLRRDRQPFTWRNAFLAIDRVLHAHERLP
WKPLRDFSLKECERWIIEHQEADGTWGVIQPPSVYSLIALRAHGYSMDHPIMQKGLNGFL
GDFALRRGNTFSVQPCLSPVWDTALAVTGLREAGVPADDESLVQAGRWLLAHEVQSLGDW
ALTVPGIEPGGFPFEFSNELYPDTDDTAEVLIALRLLDLRGKDGPFHRSKVWLRAMQSTN
GGWGAFDRDNNDEFVSRIPFADFGATFDPPTEDVTAHILEAFALDGTPPSDEMMDHALDY
LWDTQEPDGSWWGRWGVNYLYGLGAAVPALVAAGVDPADPRLRRAVRWLEHHQQSDGGWG
ESCATYEDPSLRGQGPSTASQTAWALLALLAVEPPDHPATVRGIDYLVRTQTDDGEWIEP
HFTGTGFPRDFMLKYHLYSNYWPLWALGRYRRLRDGNPIHLPETDPLG
>A0A3R9Y1S3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. WAC05374|TrEMBL
MTATTDGSTGALEPRAPSATTTTTTAPGDLREVAERAARRSIDHLLAQQDDEGWWKGDLE
TNVTMDAEDLLLRQFLGIQDEAVTRAAALHIRGRQREDGTWATFYGGPGELSATVEAYVA
LRLAGDRPDAPHMARAAAWIRDRGGIAAARVFTRIWLALFGWWRWEDLPQMPPELIFLPK
WFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPSVPNPPRALAPAGSWEG
AFQRLDRALHAYHRIAPRRLRAAAMNTAARWIVERQENDGCWGGIQPPAVYSLIALHLLG
YDLEHPVMRAGLESLDRFAVWRDDGARMIEACQSPVWDTCLATIALADAGLRPDHPALVK
AADWMLGEEIVRPGDWAVRRPGLTPGGWAFEFHNDNYPDIDDTAEVILALRRVRHPHPEQ
IEAAVRRGATWTAGMQSRDGAWAAFDADNTSPFPNRLPFCDFGEVIDPPSADVTAHVVEM
LAHEGKAHHPRTRRGIAWLLAEQEASGAWFGRWGVNYVYGTGSVVPALTAAGLPPSHPAI
RRAVAWLESVQNDDGGWGEDLRSYREQEWIGHGASTASQTAWALLALLAGGERESGAVER
GVRWLAETQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGEPAIGRLGK
GA
>J2A3I3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces auratus AGR0001|TrEMBL
MTATTDGSTGALPPRAPSASDATAEKKAASARTRNALREDTADAARRASARATDHLLSLQ
DPAGWWKGDLETNVTMDAEDLLLRQFLGLQDPELTQAAARYIRGEQCPDGTWATFYGGPG
ELSTTIEAYVALRLAGDAPDAPHMAKASAWVREQGGIAAARVFTRIWLALFGWWKWDDLP
QLPPELLYFPKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPRRPNPP
RPLAPAASWDGVFQRLDKALHLYHKVAFRRLRRAAMRSAARWIIERQENDGCWGGIQPPA
VYSVIALHLLGYDLDHPVLRTGLASLDRFAVRRADGARMIEACQSPVWDTCLATIALADA
GVPADHPQLVQAAEWMLAEQIDRPGDWSVRRPQLPSGGWAFEFENDNYPDIDDTAEVVLA
LRRVKHPDPQRVEAAVRRAVRWNLGMQSKDGGWGAFDVDNTSPLPNRLPFCDFGEVIDLP
SADVTAHVVEMLADVGRTHDPRTRRGVAWLLAEQDPCGAWFGRWGTNYVYGTGSVLPALA
AVGIPRSHPAVRRAVRWLEGVQNDDGGWGEDQRSYQDKERWAGRGASTASQTAWALMALL
AAGERDGEAVRRGVRWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRY
LNGGPAVAPVGA
>R9W2N8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAQAVFPLGDTGVSRNDPRLQKAADWLLSKEVRHKGDWAMKVPNTEPGGWYFEFN
NEFYPDVDDTAQVLLALKAVDNPRERYQHQVAQRAIDWEFAMQCRNGGWGSFDKDNTKMI
FQYVPFADHNAMLDPPTVDITGRTLEMLASYGYTQEDKRVQKAIKFILEEQEPDGSWFGR
WGVNYIYGTFLVLRGLEAIGVCHNEPQMLQAAEWIRMVQNPDGGWGE
>A0A4Q5P5H9|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobiaceae bacterium|TrEMBL
MSSIASELTAGKAKLESSIASAKQSLQSFQQSDGHWVFELEADATIPAEYVLMRHFLAEP
VDAELEGKIANYLRRIQGAHGGWPLVHDGAFDMSATVKAYFALKMIGDDIDAPHMKRARE
AVLERGGAIRANVFTRFLLSMFGVLSWRSVPVLPVEIMHLPTWFPFHLNKMSYWARTTVV
TLIVLAAKKARAKNPKGIGVDELFLQDPRSIRTLERAPHQNRAWFAFFSGIDALLRVAEP
YFPAKYRQSAIDKAIAFFEERLNGEDGVGAIFPPMANAVMIYDILGYPEDYPKRAVQRRG
IDKLLVIKDHEAYCQPCVSPVWDTALTAHAMLEAGGEETLVQAKRGLDWLVPRQELEVKG
DWAANRPNLRPGGWAFQYNNAHYPDLDDTAVVVMAMDRARRMTGGKDYDTAISRAKEWIL
GMQSSDGGFAAFDVDNNHEYLNNIPFSDHGALLDPPTEDVTARCVSMLAQLGDTVETSKP
MADAVDYLRRTQLAEGSWYGRWGLNYIYGTWSVLCALNIAGVPHQDPVMRKAVSWLYAIQ
NEDGGWGEDAVSYRLDYKGFESAPSTSSQTAWALLALMAAGEADNPAVDRGIRYLMATQN
EKGLWDEARYTATGFPRVFYLRYHGYSKFFPLWALARFRNLQSTNSRTVGVGM
>G4SWI8|squalene-hopene cyclase|EC 5.4.99.17|Methylotuvimicrobium alcaliphilum (strain DSM 19304 / NCIMB 14124 / VKM B-2133 / 20Z)|TrEMBL
MLIETIFHPDQDASSTSLSYPRLSLNDAITCAKARLLELQNEEGYWVFELEADCTIPSEY
ILMMHFMGEIDATHQAKIVQYLHEQQDRDGSYPLYKGGPGDLSCTIKAYYAMKLAGDSIQ
AQHMVKARRWILARGGGAKANVFTRIMMAMFEQIPWRGVPFIPVEIMLLPKWFPFHIDKV
SYWSRTVMVPLFILCTYKVKARNPNNVGISELFITQPESEKNYFAHVKTPLGKSILAADR
MGRLMEPLIPGFVRRKATIKARDWFMSRLNGYDGLGAIFTSMVNAYEAMDYLGIPADDER
RRIAREAIDRLLVVKPDKAYCQPCVSPVWDTGLAVLVLQEVDRRERDPIAEQSLTKALNW
LAGRQLSNEPGDWRVQRPNLPGGGWAFQFGNSHYPDVDDTAVVALAMIESGDREFAENIE
RAGVWIAGMQSANGGYGAFDADNTHSYLNHIPFADHGALLDPPTADVSGRCVMFLSKLVD
RQPEYRAVIDTCITYLRNQQEADGSWFGRWGTNYIYGTWSVLTGFESAGISKHDSHIRKA
VVWLKSKQRADGGWGEDNDSYHDVGVRGESETGSAFHTALALLALMSAGEAGCPEVKSGI
NYLLKNQQDDGFWKDDGFNAPGFPKFFYLKYHGYEKYFPLWALGRYRNECGDFIS
>A0A4D7DHG7|squalene-hopene cyclase|EC 5.4.99.17|Novosphingobium sp. EMRT-2|TrEMBL
MTDPLAAVDAAVDRAASALSRAQRADGHWVFELEADCTIPAEYVLLRHYLGEPVAEELEA
KIGRYLRRTQSAEHHGWGLFHKGAFDVSATVKAYYALKMIGDDPAAPHMVRAREAVHKAG
GAEAVNVFTRIQLALFDAGPWSAVPTMPPELILLPRWFPIHLSKMSYWARTVVVPLLVLC
AKKPVARNAKGIKVDELYTRRPIDRKTQAADPKWVWTKSFNALDKVLKVAEGHWPRTLHQ
RAIDTCAAWVTERLNGEDGLGAIYPAMANSVMMFDVLGYPEDHPARAIARQSVENLLVIH
EDEAYCQPCVSPVWDTALAAHAMLEAGGADNVARAEAALDWLKPRQVLDVEGDWAEERPG
VRPGGWAFQYNNAHYPDLDDTAVVVMAMDRAQVADRMPIDRGVEWTVGLQSRNGGWGAFD
ADNDYDYLNNLPFADHGALLDPPTADVSARCVSMLAQLGEGLDSPRMAAAIAYLRKEQEP
EGSWFGRWGVNYIYGTWSVLCALNAAGLPADDPAVARAVGWLKAIQNPDGGWGEDCDSYA
LDRKGHVPAPSTASQTAWALLGLMAAGEADSEAVERGVDWLVANQEADGLWGQEYYTGGG
FPRVFYLRYHGYPKYFPLWAVARYRNLKRSNTRQVAFGM
>A0A7Y8HSV0|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
MKLIRTLLDRLSDGLFVSVPEMRGLATELSNVPPLRLVSDKSVLTAPVDSATRRQANPIS
QVDTLDDAVRRSQAWFLSRQHASEGYWVAELEADTTLTAEYLMLRRFLDRVDPERERRAV
GYLRAMQLPDGGWPIFYGGPSEISASVKAYFALKLSGISADEPFMLQARDRILAMGGVVQ
TNVFTKIALAQFDQYDWEGIPHMPVELMLLPKGFYFNIYAISYWSRTVLTPLLIIFAHRP
VCQIPREQGIEELYLIPRKEIRYWKFPPFNKDQKWFTLHNFFVALDAMLKLYDRVPLMWL
REKALHRATTWMLEHMKGSGGTGAIYPAMANSIVALRCLAYQVDDPLVQKALHEIEMLEV
YDTVSIGDQRAEALHLQPCHSPIWDTALLVNALIETGMPEDHPSLQKAAAYLLSRQTKTV
GDWKFSSPDAEPGGWYFQFENEFYPDVDDSAVVVMALSKVQMGQTVTLQDSIRRGMNWVL
AMQGSDGGWGAYDKDNNRVVFNYIPFADHHALLDPSTSDLTGRCLEMLGALGYDQTHPAV
APALRFLKREQEADGSWYGRWGVNYIYGTWSVLAGLRAIGEDLSQPYIRRAVAWLESKQN
PDGGWGESCLSYGDPAWSGKGDSTPSQTAWAIMGLMSAGMSDAFSVARGVQYLLRHQMKD
GSWEEVRHTGTGFPRVFYLRYHWYCRYFPLWALAMYRNLRTRGKMRADEVRQQVLASGCH
RAGR
>A0A7C4FXM5|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Acetothermia bacterium|TrEMBL
MPGVKERKDPREYLIVDRPAPSTHGRSGVEDLDEAISRAVDWLLSRQSPEGWWWAELESN
VTITAEHLFLTHILGIGSQDLWDKIARYILSAQRPEGFWANWYGGPGDLSTSVEAYVALK
MAGVDPNSPPMKKAREWILSQGGVEKARVFTKIWLSMLGEWPWDATPMLPPELVLLPERF
PVNLYSFASWARGTILPLAILRVLKPVWPIPPHARIDELFARGRANADLSIPRKKSLWGR
FFYGVDKALRLYERRPLRSLRRLALKRAEEWIVERQEADGCWGGIQPPWVYSLLALYALG
YSLESPVLAKGIAGFERYSIEDERGFRLQSCISPVWDTGLALLALQDAGLPPDHPALIRA
GSWLLGEQIFVGGDWQVKCSARPGGWAFEFDNDVYPDTDDTAVVLMALLGVSLPERAKDF
ALKRGLEWLLGMQSKNGGWGAFDRNNTKTFLREIPFADFGELLDPPSEDVTAHIVELLGR
LGYRPGFEPLDRALRYLFREQKAEGPWYGRWGVNYLYGTGAVLPALRAVGFPMNDPRVRR
AVEWVLSRQNPDGGWGXDVLSYHKKELWGRGPSTASQTAWALLALLAAGEAKNPAVRRGV
EYLIRTQNDEGTWNEPYYTGTGFPTDFMIRYHLYRHVFPLMALGRYRKAVTGDK
>A0A3R7SDA5|squalene-hopene cyclase|EC 5.4.99.17|Pelagibacteraceae bacterium TMED195|TrEMBL
MHCLEKIIKPFEGLIKKRIKDQNNNKLREGCYVYELEADSTIPSEYILLMHFIGDINVKL
ERKIQKYLLNKQNNDGGWPLFFDGESDISASVKAYYALKLSGLKKNNPSLVNAKTFILKN
GGAENANVFTRISLALFGQISWISVPYMPVEIINFPRWFPFSIYKISYWSRTVLIPLLVI
MNKKPLANNPSNISIEELFIDPNTSPSVKAINSSGFFSFLFLILDKVARFFFPNFVSKNY
KKRCIDNIYEWISKRLNGKDGLGGIFPAMVNALIAFKIDEKNRYEKQIKICKEAIDNLIV
EKKDFAYCQPCLSPVWDTGWMGHVLLEQNENVDDLVTWFLNKEIKSAGDWNVHKKNLAPG
GWAFQFNNDYYPDVDDTALVGMFLDRYNRKKKIKKVEQCLERTRKWIISMQSKNGGWGAF
DIDNTKYYLNSIPFADHGALLDPPTVDVSARCLSFLKQQNNPESQLSINKGLKYLLSKQE
NDGSWYGRWGTNYIYGTWSVVSALNLLDFPQKEDVFQKASNYLKGMQKTDGGWGEDGKSY
YKGYESYSKSSTPSQTAWAIMGLISIGEIDCKEVEKGIKYLLKNRLNWTEESYTAVGFPK
VFYLKYHGYAEYFPLLAISKIKNQLKKNSIFPNYGT
>A0A3R9TTZ7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. WAC05858|TrEMBL
MTATPTVQPSESSESKTLSVAREATARAVEHLLSRQDERGWWKGDLETNVTMDAEDLMLR
QFLGIQDPDTLDAAARFLRSQQGADGTWASFHGGPPELSTTIEAYVALRLAGDEPDAPHM
AAASAWVRSRGGIAAGRVFTRIWLALFGWWRWEDLPELPPEIIYFPKWLPLNIYDFGCWA
RQTIVPLTIVSAKRPVRPAPFPLDELHTDPRRPNPPRPPAPIASWDGAFQRLDRALHAYH
KVAFRPLRRAALRSCARWIVERQENDGCWGGIQPPAVYSVIALHLLGYDLDHPVMRAGLE
SLDRFAVWREDGSRMIEACQSPVWDTCLAAIALADAGLAPDHPALVKAADWMLAEQIDRP
GDWSVRRPGLPSGGWAFEFHNDNYPDIDDTAEVVLALRRVDHPEPERIEAAVRRAMRWTL
GMQSKNGAWGAFDVDNTSPLPNKLPFCDFGEVVDPPSADVTAHVVEMLAHEGRTYDARTR
RGIAWLLSEQEPSGAWFGRWGTNYVYGTGSVVPALIAAGVPASHPAVRRAVRWLESVQNE
DGGWGEDQRSYLDAEWMGRGASTASQTAWALLALLAAGERDGAAVERGVTWLAETQREDG
SWDEPYFTGTGFPWDFSINYHLYRQVFPVTALGRYVHGEPTGARPRSG
>A0A5D0U304|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura syzygii|TrEMBL
MTATQQTPRSTDTIEPRTAADALDAAREHLLLLQSPQGWWKGELQTNVTMDAEDMLLREF
LGIRTDDDTREAARWIRSQQAADGSWANFHDGPPDLSTTVEAYVALRLAGDPPDADHMLR
AAAHVRSAGGVPATRVFTRFWLAMFGRWPWDELPVVPPEMIFLPRWFPLNVYDFACWARQ
TIVPLTVVAALRPVRPLPFALDELYPGYDVPRPRDRARPGWDMAFRTLDRALHVYERRPV
KGLRRAALRRAAEWIVARQERDGSWGGIQPPWVYSLIALNLLGYGVDHPVVQRGLDGLER
FTIRDDEGRRLEACQSPVWDTVLAMTALSDAGLPAGHPALERAADWVIGEEVRGPGDWSV
RRPGLPPGGWAFEFDNDVYPDVDDTAEVVIALDRVRHPLAEPAIERGVRWMAGMASKDGG
FAAFDADNTRALCRRLPFCDFGEVIDPPSADVTAHVVEAMAHRGMADSLLVKRAVVWLLK
AQEPDGSWFGRWGANHVYGTGSVVPALVAAGVRPDKPVIKDAVGWLERHQRDDGGWGEDL
RSYRDRSWVGHGASTASQTAWALLALLAAGERGEAAERGVRWLVDHQRPDGTWDEDHFTG
TGFPGYFYINYHLYRLVFPLSALGRYLKGS
>A0A088UFX4|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cenocepacia|TrEMBL
MNDLTDMATLSAGTAPADLEAAVARATDALLAAQNADGHWVFELEADSTIPAEYVLLVHY
LGETPNLELERKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPKYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKSIEKLLVVHDDEAYCQPCLSPVWDTSLAAHALLETGDTRAEDAALRGLEWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMERAQQLKQNDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETAL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLGPDDARVKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGYEQAPSTASQTAWALLGLMAAGEVNNPAVKRGIDYLI
AEQKEHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A0L0MJ97|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Burkholderia verschuerenii|TrEMBL
MNDLSLSAETTPPANATAATAATAETLATPVTRALPDSALDATINRATDALLAAQLPDGY
WLYELEADATISAEYVLLVHYLGEQANPELEAKIGSYLRRIQRENGGWPLFADGAMDVSA
TVKAYFALKMIGDSPDADHMQRARGAILAAGGAEKVNVFTRILLALFGVVSWRAVPMMPV
EIMRLPMWFPFHLSKVSYWARTVIVPLLVLNAKRPRARNPRGVRIDEVFRDLPVNTGMPS
RSGHQSRGWFAFFRVVDSILRVADPVLPKGVREQAINEAVRFVDERLNGEDGLGAIFPAM
ANSVMMYDVLGYPPEHPNRAIARKSLDKLLIIDDADDGEAYCQPCLSPVWDTSLAAHALL
ETGMPKARAAVSRGLEWLRPLQILDVRGDWISRRPNVRPGGWAFQFANPHYPDVDDTAVV
AMAMERADRENGTAMYGEAIARGREWIVGMQSGDGGWGAFEPENTHEYLNNIPFSDHGAL
LDPPTVDVSARCLSMLAQLGETPANSEPARRALDYIVKRQERDGSWYGRWGLNYVYGTWS
ALCALNAAGIGPDDSRVKRGADWLIAIQNADGGWGEDGESYKLDYRGYEQAQSTASQTAW
AVLGLMAAGRVDDPAVARGIDWLLKTQQDHGLWDETRFTATGFPRVFYLRYHGYRKFFAL
WALARYRNLTREGLTRVSVGM
>A0A7X0VHE7|squalene-hopene cyclase|EC 5.4.99.17|Cohnella nanjingensis|TrEMBL
MSPILIKIDEEIQRLTETLLQLQQQDGSWRFCFENGTTIDAYAIILFRTLNVQNEALIRQ
LHDRILNEQQHEGCWKLFPDEEEGNLSASVEAYYALLYSGYSQTTDEPIRRAKRFIQSKG
GLGKVTSILTKAILAATGQSKWPSSISSIPLEILLLPASFPINFFEFSAYSRVHLISMLI
MADRHYSIKTDHAPDLSDLHVDPMNTDEQPARAFQEMQISIQAGLSRLIGTPRSIHEAAT
TKAQQFILQRIESDGTLYSYASSTILMIYALLALGYDQQHPVITLAVQGITAMQCRSNGK
TTIQNSPSTLWDSALITYAMQEAGIADDHATIRSAAAYLLSRQHHQSGDWSIHNPNTLPG
GWGFSETNTMNPDVDDTTAALRAIRRLSHTDPSYRESWNRGLNWVLSMQNNDGGWPAFEK
NTNNEMLTWLAIDGAKSAAIDPSEADLSGRTLEYLGNFAGLDTRYDFIKRGTNWLINHQE
NDGSWYGRWGICYIYGTWAAITGLMATNIPTNHEAVQKGAQWLLNIQNADGGWGESCRSD
RLQHYVPLGESTPSQTAWALDALIAVHPRSTAAMDKGIYRLIASLQEDKWTASYPTGAGL
PGNFYVHYHSYRYIWPILTLSHYRRKFGHQA
>A0A4V2ZMT2|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus sp. L7L|TrEMBL
MSINETALGTTAPPVRVAADPAFAPAFAQRSAAQELDHGIGLAVDALLHQQRPDGHWVYE
LEADATIPAEYVLLVHYLGEAPDLALEARIARYLRRIQNADGGWPLFHDGKADISASVKA
YFALKMAGDDPQAPHMARARQAIHAMGGAEASNVFTRTLLALYGVMPWSAVPMMPVEIML
LPRWFPFHLSKVSYWARTVIVPLLVLNSLRPRARNPRGIGIDELFSNPRRSVGLAPRAPH
QHAGWYNLFRGLDALLRVAEPAFPGVLRRCAIAAAQRFVRERLNGEDGLGAIFPAMANSV
MMFDVLGVPADDPARAVARHSVERLLVEHGDEAYCQPCLSPVWDTALAAQALLETGEARA
AAAVGRALDWLKPLQVLDVRGDWSVRRPRVRPGGWAFQYANAHYPDVDDTAVVAAAMDRY
MREHAAPGRYDEAVARAAEWIVGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDPPTA
DVSARCLSMLCQTGATPASSEPAARALRYLLAEQLPDGSWFGRWGTNYIYGTWSALCALN
AAGLGPDAPAVRRAADWLAGIQNDDGGWGEDGASYRLDYRGYESAPSVASQTAWALLALM
AAGAVQHPAVARGIGYLLRTQRPPQEGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWAL
ARYRNLRRGGDGGGEGVAEGRVAWGL
>A0A6G2SR90|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8359|TrEMBL
MTATTDGPAGAAELSATTAGHPDRTTLAPDEVLAAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPSDLSATIEAY
VALRLAGDAPDAPHMARAASWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFL
PSWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPARPNPSRKLAPAASW
DGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIVERQENDGCWGGIQPPAVYSLIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMVEACQSPVWDTCLATIALVDGGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARVEAAIERGVRWNLGMQSRNGAWGAFDADNTSSFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGRARHPRTRRGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALIAAGLPAAHP
SVRRAVEWLESVQNDDGGWGEDLRSYREEKWIGHGESTASQTAWALLALLAAGRRDSVAV
TRGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRT
GAAQGA
>A0A344U952|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces globosus|TrEMBL
MRAGSRTGNRGGAGRTAPARPAGADLPQPAGPPGVHDAAARAVRHLLDRQDPAGWWKGDL
ETNVTMDAEDLLLRQFLGIRDEATTAAAARHIRGGQRADGTWATFHDGPPDLSATVEAYV
ALRLAGDAPDAPHMARASAWIRAHGGIAAARVFTRIWLALFGWWSWDHLPELPPELVFLP
PWVPLNIYDFGCWARQTIVPLTVVSALRPVRPGPFALDELHTDARRPVPPRTYAPLATWD
GLFQRMDRALHLYRRFAPRPLRQAAMDAAARWIIERQENDGCWGGIQPPAVYSLIALHLL
GYDLGHPVMRAGLDSLDRFAVWREDTAPGPDGLPAGPAPVRMVEACQSPVWDTCLAAIAL
ADAGLPPDHPALVKAADWMLGEEITRTGDWAVRRPGLAPGGWAFEFHNDNYPDIDDTAEV
VLALRRVAHPDPDRLDAAVDRAVTWTLGMQSGDGAWAAFDADNTSTLPNRLPFCDFGEVV
DPPSADVTAHVVEMLAAEGRAHDPRTRRGITWLLDRQEPDGSWFGRWGTNYVYGTGSVLP
ALAAAGIPASHPAVRRAVAWLESVQNDDGGWGEDQRSYQDPRTWAGRGASTPSQTAWALM
ALLAAGERGSKAVERGIAHLVRTQLPDGTWDEPHFTGTGFPWDFSINYHLYRHVFPLTAL
GRYLYGDPFTPGTH
>A0A8F5B8H1|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura graeca|TrEMBL
MTTTEPTETTTPAKATASAKTTEHAKTTEPARTTEHARTTAPAATGPAREAPAEDTRAAA
KAALDAARDHLLGLQSPEGWWKGELQTNVTMDAEDLLLREFLGVRTEEDTREAARWIRSQ
QAADGSWANFHGGPPEPSTTVEAYVALRLAGDSPDAGHMRRAAAHIRAHGGVPATRVFTR
FWLAMFGLWSWDDLPVLPPEMIYLPRWFPLNVYDWACWARQTIVPLTVVGSLRPVRPLPF
GLTELEPAPRPGGAPPRGRRLPGWDEAFGALDRVLRVYQRRPAGRLRRAALRRAGEWIIA
RQEPDGSWGGIQPPWVYSLIALHLLGHDVDHPVMRRGLAGLDRFTIRDETGRRMEACQSP
VWDTVLAMIALSDAGVPAGHPALERAAGWVLGEEVKGPGDWQVRRPGLAPGGWSFEFDND
YYPDVDDTAEAVLALSRAAGPEARPAIERGLRWMAGMVSSDGGFGAFDVDNTRALCRRLP
FCDFGEVIDPPSADVTAHVVEALCEQGMGDSALCRRAVVWLLKAQEPDGSWFGRWGANHV
YGTGGVVPALIAAGVRPGGPVIRRAVAWLERHQRDDGGWGEDMRSYRDPAWIGHGASTAS
QTAWALLALLAAGERGPSVDRGIAWLTTRQRPDGTWDEDHFTGTGFPGDFYINYHLYRLV
FPVSALGRYVNATKGNGS
>A0A534J497|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MSRKAGASAALAGTEVLLRADAPARKLPGEKLSPLEYAIAAARDELIRLQRPDGSWELEL
EADCTIPAEYIMMMHFLGELDSALEAKLAAYLRQRQAGYGGWPLYHGGAFDMSCSVKVYF
ALKLAGDDPESPHMARARAAILERGGAASCNVFTRIALALFGQLPWRGVPYIPVEIMLLP
RWFPFNIHRVSYWSRTVMVPLLILCTLKPRARNPRNVDIRELFTTPPSQERRYFRRPLGG
SAALARVFFSLDRLARSLDGLIPRALREHALKRAEAWMLERLNGEDGLGAIFPAMVNALE
ALAVRGYSPDHPHRRGAKRALEKLLVEDYSSAYCRPCVSTVWDTALAGLAMQEEGSAGAR
AAALRGLEWLEPRQLLDDPGDWRTRRPHLPGGGWAFQRANSYYPDLDDTAAVAWSMHRST
DPGRFSFALSRALDWLVGMQSENGGFASFDVDNTSYYLNEIPFADHGALLDPPTSDVTAR
VVTALARVGRPEDRVALTRAIDYLRREQEANGSWFGRWGTNYVYGTWSVLSAFAEARIGP
DDPAVERAVSWLESRQNPDGGWGESNDSYEPGRAGTSAPSTPHQSAWAVLALIAAREAGS
DAVRRGIEYLLRTQRPDGLWSDPSFTAPGFPRVFYLRYHGYCAYFPLWALAAYRNSTAAG
PGTVH
>A0A7W7ZDB3|squalene-hopene cyclase|EC 5.4.99.17|Granulicella aggregans|TrEMBL
MNEITSNPQAVPQPAKTAHGRTQPRFGRMDLGLEHVVAGIERAKDWLLGLQHPDGYWCGE
LEADSMLESDYIFMHKLLGTGDPGRMERAVNEILRHQNADGGWSIYPNGPSNISLGVKAY
FALKLMGWSKDHPVLVKARKWILANGGVVEVNTFTKIYLCFMGQYEYDAVPAVPPELILF
PNWFYFNIYEISAWSRAIVVPLSIAYAKKPFKKVAPDQGIEELFVGGRANANLHLRWDKK
RLFGWRNVMLAFDRMAHWLEMVHIRPLRALSIKRAEKWLLERFEMSDGLGAIYPAMMNAI
IALRCLGYTNDDPQFIRAMDEFERLGLDFPNGEPDYPTPTFRMQPCVSPVWDTAQAVFAL
GEAGLDKNDPRMIKAAGWMLDKEVRHRGDWANNVPNVEPGGWYFEFNNEFYPDVDDSAQV
LMALKCVEHPSQKLQHGASTRAIDWIFAMQCRNGGWASFDKDNTKKIFEYIPFADHNAMI
DPPTVDITGRILEMLASYGYTRRDKRVEAGVQFILREQESDGSWFGRWGVNYLYGTFLVL
RGLEAMGYWNHEPAIQQAAEWIRMMQNNDGGWGESCGSYDDALQKAIGPSTPSQTAWAVL
GLLAAGDTRSDSVAKGIRWLVSKQAENGSWDESAAGRNGEAVYTGTGFPRVFYLAYHLYR
DYFPLLALTTYKKAMEREAEAA
>A0A3A9YMH7|squalene-hopene cyclase|EC 5.4.99.17|Micromonospora musae|TrEMBL
MTELLSAKTATVDPGPPAGPDPLDAAREALRRAREHLLGLQDDEGWWKGDLATNVTMDAE
DLMLRQFLGIRTAEQTDETARWIRSQQLPDGSWATFHGGPGDLSTTIEAYVALRLAGDTV
EASHMAAAAAFVRAHGGLAASRVFTRFWLAMFGHWPWSRLPAVPPELVLLPSWMPFNVYD
FACWARQTIVPLSIVRALRPVRSLGFGVDELRTSAPPPRPPRLGTRPGLLHRLDRLAGSY
ERIARGPVRRHALRRAAEWIVARQEADGSWGGIQPPWVYSLMALNLLGYPLDHPVLRAGL
EGLERFTIRTRTPDGPVRWLEACQSPVWDTALAVTALADAGLPAGHPALERAGRWMLDEE
IRVRGDWAVRRPNTPPGGWAFEFHNDGYADTDDTAEVIMALRRTGVPVEPAVLRATRWML
GMQCRDGGWAAFDADNTRKLLADLPFCDFGEVTDPPSADVTAHVVEALVAENYAGTLPVR
RGVHWLLRAQEPDGSWFGRWGANHVYGTGAVVPALVAAGVPRRHPAIRRAVDWLLAHQGA
DGGWGEDLRSYRDPSWVGRGESTASQTAWALLALHAAGHGTGEPALRAVRWLVQTQRPDG
GWDEPHFTGTGFPGDFYINYGLYRLVFPISALGRILDTGAGDLEATVTR
>A0A7X9QQB0|squalene-hopene cyclase|EC 5.4.99.17|Bacillus sp. DNRA2|TrEMBL
MTFTNVESGIQRLIEQLKKDQSPLGTWEYPFETGISTDAYMIILLRTLEINDEELIQQLA
RRIMHRQQDNGAWKLFDDEGTGNITTTVEAYYSLLYSGFYKSSSPELERAKRFILAKGGL
DNIHMFAKIMLCLTGQMKWPTFFPIPVEFMLLPNSAPVNFFSLSVFGRANLSPIMILADK
KCSIRTAKSPDLSHLRINRQLQVHDEELNFSRSTKWQTLASIIEQGLTAVIGLPSRMKKV
ATQKAKQYMLDRLEGDGTFLNYFSSTFLMIFALLALGKSKNDPLITKAVSGLINLRTKID
GHTHIQYTTATVWNTALISTALQEAGVSTQDPSVLRANQYLLSQQQTKFGDWQLHNQQGK
PGGWGFSHINTFHPDIDDTTAALRAVARSVRLKREARFAWEKGIKWLVSMQNDDGGWPSF
ERNINQDWLELLPFEKAEFLIADPSTPDLTGRTLQFFGHYTKLADNHPIITRAIQSLFEQ
QEKNGAWYGRWGICYLYGTWAALTGLSAVGVHAKHPSIEKAITWLEAQQNQDGGWGESCL
SDEVKRYVPLSNSTLTDTAWAVDALISVSNVATQSIEAGIHYLLRSLERNDWTTAYPKGQ
GMAGGFYIHYHSYRYIFPLLALSHYRNKFL
>A0A4P9USV2|squalene-hopene cyclase|EC 5.4.99.17|Methylotuvimicrobium buryatense|TrEMBL
MFTDATTEINTRDLPSSATAIVAKPNDLSKAIGKAQDYLLKLQQPDGHWIFELEADCTIP
SEYIMMMHYLGEIDEVLQAKIANYLRSRQSEDGSYPLFTGGPGDISGSVKVYYALKMAGD
SIDAPHMQKLRNYILSQGGAARANVFTRIALAIFEQLPWRGVPYIPVEIMLLPKWFPFHL
DKVSYWSRTVMVPLFVLCSEKATAKNPNKVDILELFVVHPDKEKHYFPERTALNKFFLML
DKLGRVTRPLIPQSMHQKALDRAQDWFIERLNGEDGLGGIFPAMVNAYEAMLLLGMPKDH
ELVVTARKAIDKLLVINEHDAYCQPCLSPVWDTGLTALALQEVDKNGNRDALIRAYDWLK
SKQLIDEPGDWQVTKPELKGGGWAFQYANPHYPDVDDTGLVAFAMADSNLPELDESIHRA
TRWIVGMQSENGGYGAFDVDNTYYYLNEIPFADHGALLDPPTVDVSARCAMLMARVAKGH
DEYRPALQRTIDYIRSEQEADGSWFGRWGTNYIYGTWSVLLGLEQTDVPKTDPMYVNAAR
WLKSVQREDGGWGEDNFSYHDEQNFRGKYRFSTAFQTAWAIIGLIAAGEAHSPEVKAGVE
FLMKTQLTDGSWNDKCFTAPGFPRVFYLKYHGYDKFFPLWALAKYRNAINNS
>A0A6P2A8S7|squalene-hopene cyclase|EC 5.4.99.17|Gloeocapsa sp. DLM2.Bin57|TrEMBL
MVLQKDNEQITQLNQAILASQNYLLSQQDPEGYWWAELESNATITAEVVLLYKIWGNDDT
KPLHKVEQYLRSQQVASGGWELFYGDGGDLSTSVEAYLALRLLGVNPSDPDLERARQFIL
QKGGISKTRVFTKFHLALVGCYDWRGVPSIPPWIMLLPNNFPFTIYEMSSWARSSTVPLL
IVFDQKPVYQIAPDFNLNELYTEGIDNVRYQFPSKNDWTDLFLWLDKLFKLGESLNLVPL
REASLKAAEEWILTRQEVTGDWGGIIPAMLNSMLALRTLGYELNDPIVQRGFKAIDDFTI
ETPDSYCVQPCVSPVWDTAWVLRALVESGINPDHPALVKGGEWLIEKQILDYGDWQIKNK
QGTPGGWAFEFINRFYPDLDDSAVVIMALQSLKLPNEPLKQATLKRGVAWMETMQCRPGG
WAAFDLDNDQNWLNYLPYADLKAMIDPNTADVTARVLEMLGCISVTMSPERVNKAIAYLV
GQQETDGSWFGRWGVNYIYGTSGALSALALISPEKHRENISKGANWLLSCQNPDGGWGET
CRSYDNPNLKGKGNSTASQTAWALIGLLAAQTVTQQSYQPHLSRGVDYLVTTQKPDGTWY
EAEFTGTGFPSHFYLKYHYYQQYFPLLALARYQQQGVF
>A0A7H8JGM3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. NA02536|TrEMBL
MTATTDGSTGAALPPRVTAASENDTDIPEAAGVPDIAAHAMRRATDFLLSRQDDQGWWKG
DLETNVTMDAEDLLLRQFLGIRDEDTTRAAALFIRGEQREDGTWATFHGGPGELSTTIEA
YVALRLAGDPPEAPHMARASAWIRERGGIAAARVFTRIWLALFGWWKWEDLPELPPELIW
FPSWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPRRPRPPRPHAPPNT
WDGAFQRLDRALHALRRAVPRRVRQAAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLRHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLAAIALADAGLPADHPS
LVKAADWMLGEQIVRPGDWSVRRPHLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHD
PERMDSAIGRGVRWSLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGLAHDPRTRRGIQWLLAEQEPDGSWFGRWGVNYLYGTGSVVPALAVAGIPGSH
PAIRRAVAWLEKVQNDDGGWGEDLRSYRHVREWSGRGASTASQTAWALMALLAAGERDSG
AVERGVAWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFSK
KQTAARNGSAQPLAGVKGSR
>A0A7X3R3S4|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
MDASGLDVCIDRSVKHLLSLQAEDGYWWAELESNATMAAEHLLLERFLGTTEEEREQGIV
RYLLGLQTEDGSWPVYWGGPGDVSITTEAYFALKLAGVDPERDEMKRAREFIRDKGGVGA
TRIFTKLWLALFGQFEWSALPAMPPESILMPVSSPLNIYMFASWARATIVAILVVWAYRP
VVPIPEYAHVDELYLDPMDRRSIPLRRDRQPFTWRNAFLAIDRVLHAHERLPWKPLRQYA
LKECERWIIEHQEADGTWGVIQPPSVYSLIALRAHGYSMDDPVMKKGLNGFLGDFALRRG
NTFSVQPCLSPVWDTALAVTGLREAGVPADDEALVQAGRWMLAHEVQSLGDWALTVPGIE
PGGFPFEFSNELYPDTDDTAEVLIALRLVDVRGKDGPFHRAKRWLRAMQSTNGGWGAFDR
DNNDEFVSRIPFADFGATFDPPTEDVTAHIVEAFALEGTPPSDEMIEQALGYLWDTQEPD
GSWWGRWGVNYLYGLGAAVPALVAAGVDPTDPRLQRAVRWLEHHQQPDGGWGESCATYED
PSLRGQGPSTASQTAWALLALLALEPPDHPAIVRGIDYLVRTQTDEGEWHEPHFTGTGFP
RDFMLKYHLYCNYWPLWALGRYRRLRDGNPIHLPDTDPLA
>A0A847JUH4|squalene-hopene cyclase|EC 5.4.99.17|Chthonomonadales bacterium|TrEMBL
MTATESMVPTSRADPPGATGAPSGEGEDYACDLDQAILRAQRWLLASQQPDGHWVGELEG
DTILESEYALLLQFLGRDDPRMLSDLTRYAVQRWQRDDGGVPIYPGGPSDVSASVKLYFA
CKLAGHSGAEPFMQRLRECILRLGGVTQCNTFTKLYLAIFGQYSWDGVPTIPPELMLAPR
WFYVNVYAMSSWSRAILIPLAIINAMRPSRPVPESCSIDELFVGDRSPASQRLRRDRRLL
SWRNVFLLIDRLLKYHERSPIKPFRAMALRRAQRWLIEHLQDSDGLAAVFPAMTHAVMAL
TCLGYPQDSPEVSHEMDELARFIIRDERGVRLQPCVSPVWDTAIAVNAMVDSSPPSAISG
EAAGAMRAAVEWLIAHEVRSRGDWSLTVGRVEPGGWAFEYRNPFYPDTDDTAMVVMALIR
ASRHFGRSESVQHAMDRAVRWVLAMQSRNGGWGSFDRDNTRVLMQYVPYADHNAMLDPPT
ADVSARVIEALAEVGLPSSHPAVQRATRFVLAEQEPDGSWFGRWGVNYLYGTWQAIQGLT
RSGLAADHHAIERASQWLLSVQNADGGWGESCASYADPSLRGVGESTPSQTAWALMGLVS
AGMARTEACRRGVRYLIEHQTPDGTWEEDAFTGTGFPCVFYLRYHLYRHSFPLWALGKYR
AAISG
>A0A515KSF7|squalene-hopene cyclase|EC 5.4.99.17|Tardiphaga sp. vice352|TrEMBL
MQSDHAEATVSNAALESSIDAARQGLLGFRQPDGHWVFELEADVTIPSEYALLRHYLAEP
VDHELERKIGNYIRRTQGTHGGWALVQDGPFDMSASVKAYFALKMMGVDPNEPYMAKARE
AIRSRGGAIHSNVFTRFMLSMFGVLTWKSVPVLPVEIMFLPFWFPFHLNKMSYWARATIV
PLMVLTAKKPRAQNLGEIDIRELFLQDPKLIGRTARAPHQSRALFAFFTGIDMLLRAAEP
FFPKKLRQRAIDKAVAFVEERLNGEDGLGAIYPPMANTVMMYEVLGFPADHPPRATTRRG
IDKLLVIGEVEAYCQPCVSPVWDTSLTAHAMLEAGGDAAFDAAKGGLDWLVPKQVLDVKG
DWAVKRPDLRPGGWAFQYNNAHYPDLDDTAVVMMAMDRARKHAGITDYDHAIDRGREWIL
GMQSRDGGFAAFDVDNLEHYLNHIPFSDHGALLDPPTEDVTARCVSMLAQLGETVQTSRP
MADAVEYLRRTQLADGSWYGRWGLNYIYGTWSVLCALNAAGIDHQDPMMRRAVTWLLSVQ
NADGGWGEDAVSYRLDYKGYEQAPTTASQTSWALLALMAAGEVEHPAVARGMRYLIDTQT
EKGLWDEARYTATGFPRVFYLRYHGYAKFFPLWALARFRNLKSTNSKTVRVGM
>A0A848IIU4|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia polaris|TrEMBL
MNDLSQAQPLDAVLPEFADAAPTASNAEPMVAPQASAGPLDAAITRATDAILAAQKPDGH
WVYELEADATIPAEYVLLVHYLGETPNLELEQKIGRYLRRIQLADGGWPLFTDGALDISA
SVKAYFALKMIGDSPDAEHMVRAREAILANGGAETVNVFTRILLALFGVVSWRAVPMMPV
EIMLLPQWFPFHLSKVSYWARTVIVPLLVLNAKRPVARNPRRVRIDELFRGAPVNTGMRD
RAPHQHLGWFRFFRGVDVMLRMVDGLFPKATRERSVREAVRFVDERLNGEDGLGAIFPAM
ANSVMMYDVLGYPADHPNRAIARQSIEKLLVIKDDEAYCQPCLSPVWDTSLVAHALLETG
EEHAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYNNAHYPDVDDTAVVVMA
MQRSAALTQSDVDREAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDP
PTADVSGRCLSMLAQLGEFPQGSEPAQRAFDYMLKEQESDGSWYGRWGLNYIYGTWTALC
SLNAAGLPHDDPRMKRAAQWLLSIQNEDGGWGEGGESYKLDYRGYERAPSTASQTAWALM
GLMAAGEVNHEAVARGVEYLQREQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWAL
ARFRHLKRNGLTRVAVGM
>A0A6M1M337|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium sp. DB0501|TrEMBL
MGKVETLQRKSTQDITLDEVERRVSAASRALTQLAHADGHWCFELEADATIPSEYILYHH
FRASVPPRELEEKIAVYLRRTQSPLHHGWALVHEGPFDMSASVKAYFALKMIGDPIDAPH
MRRAREAILQRGGAAHANVFTRTLLALYGEVPWSAVPVMPVEVMLLPRWFPFHLDKVSYW
ARTVMVPLFVLQVKKPRAKNPRGIGVRELFTQDPERIRRWPSGAQESSPWRPVFAAIDDI
LRVVEPFFPKKPRARAIDKAVAFVSERLNGEDGLGAIYPAIANSVLMYEALGYPEDHPLV
ATARSAVEKLVTVKEHEAYVQPCLSPVWDTALAAHALMEAGGPENERQARAALEWLKPLQ
VLDIKGDWAARKPDVRPGGWAFQYNNAHYPDLDDTAVVAMAMDRAQTRLGPGEGGSDYTQ
SIARAREWIEGLQSRDGGFAAFDADNTHHYLNYIPFSDHGALLDPPTADVTARCISMLAQ
LGETKETSPVLARAVDYLLADQEEDGSWYGRWGMNYIYGTWSALCALNAAGHDPASAPVR
KAAEWLVGIQNPDGGWGEDAASYKLEYRGYERAASTASQTAWALIALMAAGEADHPAVAR
GVNYLARTQGADGLWGEEFYTGTGFPRVFYLRYHGYAKFFPLWALARYRNLQRGNSRKVA
VGM
>A0A6P0MLU0|squalene-hopene cyclase|EC 5.4.99.17|Symploca sp. SIO2C1|TrEMBL
MQTQDRITTESTIADAIANSQNYLLNLQYPEGYWWAELESNVTITSEVVLLHKIWGTDQE
RPLQKVEAYLRSQQREHGGWELCYGDGGEISTSVEAYMALKLLGVPATDPAMLRARKFIL
ERGGISKTRIFTKFHLALIGCYDWRGVPSIPPWVMLLPENFLFSIYEMSSWARGSTVPLL
IVFDHKPVYQTNPAITLDELYTEGADNVRFELPRNGDWTDLFVVLDDAFKLAENLNLVPL
REAGLEAAERWVLERQEVTGDWGGIIPAMLNSLLALRSLNYDVADPIVVRGLEAVDHFAI
ETADTYLTQPCISPVWDTAWVMRALVDSGIAPNHPALVRAGEWLLSKQILDYGDWAVKNP
QGKPGAWAFEFENRFYPDLDDSAVVVMALDAVQLPKENYKQAAIARAVAWMASMQCQEGG
WAAFDINNNSDWLNYLPYADLKAMIDPNTADVTARVLEMLGSCNLSMEQGKVDQAIAYLI
KEQETDGSWFGRWGVNYIYGTSGALSALSVIAPQKHRLNIERGAAWLVGCQNADGGWGET
CRSYNDPALKGQGDSTASQTAWALIGLMAAGKAIDNWETEAITKGINYLVTTQLADGSWN
EDYFTGTGFPCHFYLKYHFYQQYFPLIALGHYQLIIDN
>A0A4P6JRH5|squalene-hopene cyclase|EC 5.4.99.17|Ktedonosporobacter rubrisoli|TrEMBL
MGAKRLNRREKSWQKRAVDQAVEWLLEHQDADGWWCGELETNVTMTAEHVLLLRFLELSV
ERIREGAIRHILSKQRVDGSWALYFGGPADLSTTIEAYVALKVLGVDTSCDMMQRALKVI
HQQGGIAKARVFTKIWLALFGQYPWSGIPSMPPELIYLSPRLPLNLYDFACWARGTIAPL
LIVLSHKPTKALGCSVAELIVPGSENHLDRVPGSGPFWWLDKLLKLYEAFAWQPGRLRAR
QNIVDWIVERQEADGSWGGIQPPWVYSLIALHIEGMGLDHPVMQRGIEGQENFVLDDEGG
WRFQACMSPVWDTAWGLRALRYAGLRRDHPSLRRAVQWLLREQIFSGGDWQVRCGPIACG
GWAFEFENDIYPDIDDTGVVVLALLEAGEREEVCKATESAARWVVATQSSNGGWGAFDKD
NMRGMVYRLPFADFGALLDPPSEDVTAHVLEMLAQLDDMDARRHIQAGLQYLRSTQRLDG
SWFGRWGVNYIYGTWCVISALVELRKRGYKVQDMIDRGVVWLVGHQNDDGGWGETCYSYE
DSTFAGIGSSTPSQTAWATLALQLAGLDHHSACTRGLEYLCQTQVSGTWEEREYTGTGFP
HDFYIKYHLYQHVFPTMALARGCQAQQG
>H0SR06|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. (strain ORS 375)|TrEMBL
MTLTSSASARAPRDPGNYQTALQSTVRAASDWLIANQKPDGHWVGRAESNACMEAQWCLA
LWFMGLEDHPLRKRLGQSLLDTQRPDGAWQVYFGAPNGDINATVEAYAALRSLGFRDDEP
PVRRAREWIEAKGGLRNIRVFTRYWLALIGEWPWEKTPNIPPEVIWFPLWFPFSIYNFAQ
WARATLMPIAVLSARRPSRPLPPENRLDALFPRGRAAFDYELPVKANAGGWDKFFRGADK
VLHALQNFGNKLNLGLFRPAATSRVLEWMIRHQDFDGAWGGIQPPWIYGLMALYSEGYPL
NHPVLAKGLDALNDPGWRVDVGDATFIQATNSPVWDTILTLLAFDDAGVLGDYPAAVDKA
VNWVLARQVRVPGDWSMKLPHVKPGGWAFEYANNYYPDTDDTAVALIALAPLRHDPKWKA
KGIDEAIALGVDWLIGMQSQGGGWGAFDKDNNQQILTKIPFCDYGEALDPPSVDVTAHIV
EAFGKLGISRNDPSMVQALAYIRKEQEPSGPWFGRWGVNYVYGTGAVLPALAAIGEDMTQ
PYISRACDWLVAHQQPDGGWGESCASYMDISAVGRGTTTASQTAWALMALLAANRPQDKD
AIERGCLWLVERQSAGTWDEPEFTGTGFPGYGVGQTIKLNDPALSERLMQGPELSRAFML
RYGMYRHYFPLMALGRALRPQGHSNTASAPSLSSRP
>A0A7W8SL15|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia sp. WSM4180|TrEMBL
MNDLSHTQPLDAALPEAADAAPNLAEAAVVANAPAVADALATATPAPVRGASPLDASITR
ATDAILAAQQPDGHWVYELEADATIPAEYVLLVHYLGETPNLELEQKIARYLRRIQLPTG
GWPLFTDGALDVSASVKAYFALKMIGDPVDAEHMVRARDAILAHGGAEHANVFTRILLAL
FGVVSWRAVPMMPVEIMLLPVWFPFHLSKVSYWARTVIVPLLVLNAKRPLARNPRKVRID
ELFRGAPVNAGMNERAPHQHAGWFGLFRCVDSVLRAVDGLLPKATRERAIRAAVAFVDER
LNGEDGLGAIFPAMANSVMMYDVLGYPADHPHRAIARKSLDKLLVIKDDEAYCQPCLSPV
WDTSLAAHALLETGEARAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYNNA
HFPDVDDTAVVAMAMYRSAALTQSDVDREAIARAREWVVGMQSSDGGWGAFEPENTQYYL
NNIPFSDHGALLDPPTADVSGRCLSMFAQLGELPQSSEPARRAFDYMLQEQESDGSWYGR
WGLNYIYGTWTALCSLNAAGMPHDDPRMRRAVQWLVSIQNDDGGWGEGGESYKLDYRGYE
RAPSTASQTAWALLGLMAAGEVDHEAVARGIDYLQREQREHGLWDETRFTATGFPRVFYL
RYHGYRKFFPLWALARFRHLKRNGLTRVTVGM
>A0A3M8RN73|squalene-hopene cyclase|EC 5.4.99.17|Acidithiobacillus sulfuriphilus|TrEMBL
MMSMHPQQRSITAFQSRLGAAIAAARGALLGLQADDGHWCFEFEADCTIPAEYILMQHYM
DERDPLLERKLAVYLRSKQADHGGWPLYYAGRFDMSASVKAYYALKLAGDDPDAPHMRRA
REAILAHGGAERANVFTRIALALFGQLPWRAVPFVPVEVMLLPRWFPFHIDKVASWSRTV
MVPLFILCSLKPQAKNFLGIGIREIFRRPPERVDDYFTHSAHGWVAWLLLLLDRFGRSAE
WLIPNRLRQKAVKKAENWFIARLNGTDGLNGIFPAMVNAHEALALLGYPPEHPYRQQTAA
ALRKLVVERADDAYCQPCVSPVWDTCLALHGLLESDGALAPELARSIDWLKERQIVDEPG
DWRAQRPHLRGGGWAFQYWNHYYPDLDDTAAVAWAMARAGREEDRPSLELAADWLAGMQS
RNGGFAAYDADNTHYYLNEIPFADHKALLDPPSSDVTGRVVAFLGIYGRAKDREVLRRAV
AYLLREQEASGAWFGRWGSNYIYGTWSVLMGLEQLNDLSLQPAMARAADWLRSVQQADGG
WGESNDSYADAGLAGLGQPSTAAQTAWACLALMAAGDQGSAALCRGIRWLEEQQGDDGRW
QDPYFNAPGFPRVFYLTYHGYRLYFPLWALARYRRLGLGACR
>A0A5D3FZ95|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura decatromicini|TrEMBL
MTTTDVSGLTGAAAAAAEAARDHLLRLQSPEGWWKGELETNVTMDAEDLLLRQFLGIRSD
AETAEAARWIRSRQRADGTWANFHGGPPDLSTTIEAYVALRLARDPVDADHMRRAAEYVR
ESGGIEASRVFTRIWLALFGLWSWDDLPVMPPELMFLPNRFPLNVYDWGCWARQTIVPLT
VLGSLRPVRALPFDLPELRTGVRPAKDERGWGRFFTGLDRVLHVYQKRPVGPLRRAAIRR
AADWIIARQEADGCWGGIQPPWVYSLMALYELGYGLDHPVIKRGLDGLDRFTIRDEKGRR
LEACQSPVWDTVLAINALGDAGVPPTDPALRRAAAWVVAEEVRGLGDWAVRRPDVPPGGW
AFEFDNDVYPDTDDTAEAILALRKVDLPEAEQPIQRAIRWLEGMASRDGGYGAFDADNTR
ELCTKLPFCDFGAVIDPPSADVTAHVVEALAGEGRAESRTVKRAVVWLLRAQEADGSWFG
RWGANHVYGTGSVVPALVAAGVPAHKPPIRRAVEWLEAHQNPDGGWGEDLRSYDDPAWIG
RGESTASQTAWALLALLAAGERSHAMDAGVRWLVDHQRPDGTWDEDQFTGTGFPGDFYIN
YHLYRLVFPISALGRYLGGAT
>A0A375C971|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus taiwanensis|TrEMBL
MSMNETALANAAPHTEAAQREPAGPAQAPATRLSAPALDHGIGRALDALLHQQRPDGHWI
YELEADATIPAEYVLMVHYLGEEPDLDLEARMARYLRRIQNPDGGWPLFHQGRSDVSASV
KAYFALKMAGDDPQSAPMQRARQAIHAMGGAEASNVFTRTLLALYGVLPWKAVPMMPVEI
MLLPRWFPFHLSKVSYWARTVIVPLLVLNSLRPQARNPRGVGINELFVGNCHTVGLPPRA
PHQHAGWYTVFRGLDALLRVAEPLFPRTLRRRAIAAAQRFVRERLNGEDGLGAIFPAMAN
SVMMFDVLGEPPDDPARAVARRSLERLLVEHGDEAYCQPCLSPVWDTALATHALLETGEA
RAAQAAGRALDWLRPLQVLDLRGDWAVRRPLLRPGGWAFQYANAYYPDVDDTAVVAAAMD
RYMRAHDAPGRYGEAVARATEWIVGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDPP
TADVSARCLSMLCQTGATPGKSEPAARALRYLLAEQMPDGSWFGRWGTNYIYGTWSALCA
LNAAGLPPAAPELQRAVAWLARIQNADGGWGEDGSSYRLDYRGYEPAPSVASQTAWALLA
MMAAGATQHPAVARGIDYLLRTQQPGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWALA
RYRNLQRGQMGQSGQLSWGL
>A0A4U0RPT5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces oryziradicis|TrEMBL
MTATTDGTPGAEIPGKPSASKTDTGARPSTKEAAEHAAQRAAAHLLSRQDPDGWWKGDLE
TNVTMDAEDLLLRQFLGIQDERITMATARWIRAQQREDGAWATFHGGPGDVSATVEAYVA
LRLAGDDPAGPRMAAAAAWVREAGGVARARVFTRIWLALFGWWRWEDLPEMPPEIIYFPK
WMPLNIYSFGCWARQTIVPLTVVAAHRPVRPASFALDELHTDPANPNPPRPPARLTSWDG
VFQRLDKALHVYRKSAIRPLRRAAMKACARWIIERQEDDGCWGGIQPPAVYSIIALHLLG
YDLDHPVLRAGLESLDRFAVWPDKDTRMIEACQSPVWDTCLATIALADAGVPADHPALVK
AAGWMLDEQITKSGDWSVQRPGVPPGGWAFEFHNDNYPDIDDTAEVVLALARVDHPDTGR
LKSAIERGVRWNIGMQSKNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTAHVVEM
LAALGLEHDPHTRRGIEWLLAEQEENGAWFGRWGVNYIYGTGSVVPALITAGLPASHPAI
RRAVAWLKSVQNEDGGWGEDLRSYSSAQWVGRGASTASQTAWALLALLSAGERDSAVVER
GVHWLARTQTEEGTWEEPYFTGTGFPRDFSINYHLYRLVFPLTALGRYVRGEPFADAAKG
V
>A0A7H1B2Z4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces xanthii|TrEMBL
MTATTDGSTGAPAPEATAATTAPAGATPDAAGARAAAGRAIQRATEFLLARQDERGWWKG
DLDTNVTMDAEDLLLRQFLGIRDRAVTEAAALFIRGEQREDGAWATFYGGPGDLSATVEA
YVALRLAGDEPEDPHMARASAWVRERGGIAASRVFTRIWLALFGWWKWDDLPELPPELIY
FPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPRNPNPRRPLAPVAS
WDGAFQRLDQLMHGYRKVALKPLRKAAMNTAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLDHPVLKAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPA
LVKAAGWMLDEQIDRPGDWSVRRPRLEPGGWAFEFHNDNYPDIDDTAEVVLALRRVNHPD
RPRLEKAIERGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGRTRDPRTRRGIQWLLAEQEANGAWFGRWGVNYVYGTGSVVPALVAAGLPKTH
PAIRRAVAWLESVQNEDGGWGEDLRSYRYEDWKGHGVSTASQTGWALLALLAAGERDSKA
AERGVAFLADTQTEDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFTDR
AAAPAEGS
>A0A3M7TWX7|squalene-hopene cyclase|EC 5.4.99.17|Bacillus sp. KQ-3|TrEMBL
MNGGFFLHNLVTSAINQIIDDLRNRQSNDGSWRFCFETGTLTDAYTIILLRSLEQPDSEW
LIERLTARILSKQEANGAWNLFTDQNDGHLSSTAESFFALLYSGHVKPDAPHMKRARKFI
KARGGLAKTGPFTRAMLALNGQISWPKLFNVPIETILLPRTSLISIYDIVGYSRVHLVAV
LTSANMKYSRQNTRTPNLRDLLTERKTENEWENDQSRSILTIIQNEVSKLIDTPKRLRKT
AFEQAEQHMLKRIEPDGLYYSYITSTFFMIYAFLALGYKKDHPVIQNAVNGIKNQVCLTT
SHSHIEFATSTVWDTALISHALQQSGVPASDPLIKTANAYLLSRQHTLYGDWSFNNPNTV
PGGWGFSDINTFLPDVDDTTAALRAIKRTVREHTMYRPVWSRGADWILSMQNKDGGWGAF
EKDTDKKRITLVPFPEAGRVLIDPSTADLTGRALEFLSKDANLLSPHPAIDRAVNWLEQN
QETDGSWYGRWGVCYIYGTWAALTGLDAAGFSQNRPSVKKAVDWLTSIQNEDGGWGESCV
SDTRNTYMPLGSSTLSQTAWAVDALTATHKKPADAVRRGVNYLVSNLNRNDWTTTYPTGA
ALPGDFYIYYHSYNYIWPLLALSNFRNKFDS
>A0A4D8RBK9|squalene-hopene cyclase|EC 5.4.99.17|Azospirillum brasilense|TrEMBL
MRVQRAEPSAKAVSGAVAEATDALIRRQQADGHWVFELEADATIPSEYLLLHHILDEIDP
ELEAGLAAFIRGRQGKDGGWPLFFGGAMDISCSVKAYFALKAAGDSPEAPHMRRACEAIL
ARGGAARCNVFTRILLAQFGQIPWRAVPAMPVEVMNLPPWSPFHISRISYWSRTVVVPLL
VVMAHRLRARNPRGIGIAELFTEPPERVRNWHSNNSRGGWATLFRALDAALHAVEPRLPA
NGRQTAIDRAVRFVTERLNGEDGLGAIFPAMVNAVLMFHCLGMPPDHPDAATARRALRGL
VVRQPGRVYCQPCLSPVWDTAIICNALLETGSPLARAAARRGADWLVDRQILDVEGDWAW
QRPGLASGGWAFQYNNPHYPDTDDTAMVVMALQRLDAERYGEPIRRARDWIVGMQSRNGG
WGAFDAENQHDFLNHIPFADHGALLDPPTSDVTARCVMMLARLGEGRDTLPTRRGLTFLE
REQESDGAWFGRWGTNYVYGTWSALEALNAAGVPHAAPAVQRAAQWLLVHQRADGGWGED
GASYWAGNPRGEGPVSTASQTAWALLGLMAAGKGNHPAVDRGIDYLLAARNAEGLWSEDP
FTAVGFPRVFYLKYHGYAASFPLWALARYQALRP
>A0A846Y735|squalene-hopene cyclase|EC 5.4.99.17|Nocardia vermiculata|TrEMBL
MTVTHTGAASRRAAVEHATARTAAVPSLGSSDPAAVRAATAAAVDLLRTSQHEQGWWKGE
LATNVTMDAEDLLLREFLGISTPEVTVPAARWIRSQQRADGTWATFHDGPGDLSTTAEAW
VALRLAGDDPTAPHMRAAARFVRAEGGIEASRVFTRIWLALFGLWSWDDLPNLPPELVLF
PSWFPLNIYDWGCWARQTVVPLTVVATLRPCRPLPFGIDELRTGAPAARRAPLTSLAGVF
QRVDTVLHTYARLPLNPVRDLAMRQAGEWILARQEADGGWGGIQPPWVYSLLALHLLGYP
LDHPALRAGIEGLDGFVVREQTPDGEVRRLEACQSPVWDTALATAALLDAGVAPGDSAVL
RATDWLLGEQITAGGDWQVRRPGLEPGGWAFEFANDVYPDTDDTAEIVIALNQVAHPDRQ
RLDAAIDRAARWTVGMQSADGGWGAFDADNTSVLPTKLPFCDFGAVTDPPSADVTAHVVE
MLAALGRSGDRECRRGVRWLIDHQETDGSWFGRWGANHIYGTGAAVPALVAAGTAPRSRP
IRRAVRWLEEHQNADGGWGEDLRSYRDAAWVGRGDSTPSQTAWALLALLAAEEDSPAVER
GIAWLVGTQRADGGWDEDLFTGTGFPGDFYINYHLYRLVFPVWALGRYLRRHPEASAPEG
VAAVDGSRGP
>F7S6H4|squalene-hopene cyclase|EC 5.4.99.17|Acidiphilium sp. PM|TrEMBL
MFDTISFDFDALDQAISRAHARLSAEQRADGHYVYELEADATIPAEYVLLEHFLDRIDPE
LEARIGVFLRGIQGNSPQNPGGWPLFHDGAMDISASVKAYFALKAIGDDPDAPHMRRARE
AILARGGAARTNVFTRIQLALFGAVPWRACPVMPVEIMLLPDWFPITIWKISYWSRTVIA
PLLVLLTERPIARNPRNVRIDELFVTPPDQVTDYIRGPYRSNWGYLFKAIDSALRPLERH
FPARSRKRAIQAAIDFITPRLNGEDGLGAIYPAMANTVMMYHTLGYSPDHPDYATAWASV
RKLVTDASYRFEGASYVQPCLSPVWDTSLAAHALAEAGSPGDAQLAAACDWLIPRQILDV
KGDWAYRKPDAPPGGWAFQYNNAHYPDVDDTAVVGMILDRNGDPAHREAVERARQWILGM
QSRSGGWGAFDSDNEFHYLNHIPFADHGALLDPPTADVTARCISFLAQLGHAEDRPAIER
GVAYLRREQEQDGSWFGRWGTNYIYGTWSSLCALNAAGVAQDDPMMVRAVEWLLARQRPD
GGWGEDCETYAHAKPGEYHESLPSQTAWALLGLMAAGQAEHEAVARGIAWLQSVQEDDGS
WTEQPYNAVGFPRVFYLRYHGYPRFFPLLAMARYRNLARGNSRQVQFGF
>A0A6M0AG58|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO4G2|TrEMBL
DFILKRGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPQWFPFTIYEMSSWARGST
VPLLIVFDQKPVFDIQPRINLDELYTEGADHAKFELPRNSDWTDLFVLLDDGFKLAEDWN
LVPFRKQGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPIVQRGLEAID
RFAIETPDSYRVQACVSPVWDTAWVLRAMVESGLEPDHPALVRGGEWLLQQQILDYGDWV
VKNPQGKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLKQAAIARGLAWIASMQC
NQGGWAAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEMLGSCNLSIESQQLEKAI
AFLIQEQEADGSWFGRWGVNYIYGTTSALSALSKIAPRTHQRSIERGAAWLVKCQNLNGG
WGETCLSYDDPSLKGVGISTASQTAWALIGLMAAGEATGNWARDAIERGVNYLVSTQQPD
GSWDETEFTGTGFPSHFYLKYHFYQQYFPLLALGRYQMSV
>B2T801|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN)|TrEMBL
MNDLSQAQPLDAILPDFADAAPSAPAPAVTGEAPTASLDAAITRATEAILAAQKPDGHWV
YELEADATIPAEYVLLVHYLGETPNLELEQKIARYLRRIQLPDGGWPLFTDGALDISASV
KAYFALKMIGDPADAEHMVRAREAILAHGGAETVNVFTRILLALFGVVSWRAVPMMPVEI
MLLPMWFPFHLSKVSYWARTVIVPLLVLNAKRPVARNPRRVRIDELFRGAPVNTGPRDRA
PHQHAGWFRFFSGVDVLLRAVDGLFPKSTRERAVRQAVAFVDERLNGEDGLGAIFPAMAN
SVMMYDVLGYPADHPNRAIARQSIDKLLVIKDDEAYCQPCLSPVWDTSLAAHALLETGEA
HAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYNNAHYPDVDDTAVVAMAMQ
RSATVTQSDVDRDAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPT
ADVSGRCLSMLAQLGELPQNSEPAQRAFDYMLKEQESDGSWYGRWGLNYIYGTWTALCSL
NAAGLPHDDPRMKRAAQWLLSIQNEDGGWGEGGESYKLDYHGYERAPSTASQTAWALMGL
MAAGEVNHEAVARGVAYLEREQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALAR
FRHLKRNGLTRVAVGM
>A0A5P9WFP5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SYP-A7193|TrEMBL
MTATTDGSTGASLRPLAASASDTATDTDITIPAAAAGVPEAAARATRRATDFLLSKQDAQ
GWWKGDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELS
TTIEAYVALRLAGDSPDAPHMTRAAEWIRSRGGIASARVFTRIWLALFGWWKWDDLPELP
PELIYFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFSLDELHTDPVRPNPPRPL
APAASWDGAFQRIDKALHAYRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYS
VIALYLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVP
EDHPQLVKASDWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRR
VRHHDPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSAD
VTAHVVEMLAVEGLAHDPRTRRGIQWLLDAQEADGSWFGRWGVNYVYGTGSVIPALTAAG
MPTSHPAIRRAVRWLESVQNEDGGWGEDLRSYRYVREWSGRGASTASQTGWALMALLAAG
ERDSKAVERGVEWLAATQREDGSWDEPYFTGTGFPWDFSINYNLYRQVFPLTALGRYVNG
EPFAKKSRTAEALTESAPAEVKGS
>A0A1N7RL58|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia ribeironis|TrEMBL
MNDLSQAQPLDDVLPDHTDAVPPAAAVEPFASAASSASSASLDAAITRATDAILAAQKPD
GHWVYELEADATIPAEYVLLVHYLGETPNLELEQKIARYLRRIQLPNGGWPLFADGALDI
SASVKAYFALKMIGDPADAEHMVRAREAILAHGGAEKANVFTRILLALFGVVSWRAVPMM
PVEIMLLPMWFPFHLSKVSYWARTVIVPLLVLNARRPLARNPRKVRIDELFRGAPVNTGM
NERAPHQHVGWFSFFRGVDAVLRAVDGLLPKATRERAVRAAVAFVDERLNGEDGLGAIFP
AMANSVMMYDVLGYPADHPNRAIARQSVDKLLLIKDDEAYCQPCLSPVWDTSLAAHALLE
TGEARAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYNNAHYPDVDDTAVVA
MAMQRSAALTQSAVDREAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFADHGALL
DPPTADVSGRCLSMFAQLGELPQNSEPAQRAFAYMLQEQESDGSWYGRWGLNYIYGTWTA
LCSLNAAGMPHDDPRMKRAVQWLLSIQNADGGWGEGGESYKLDYRGYERAPSTASQTAWA
VMGLMAAGEVNHEAVARGIDYLQREQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLW
ALARFRHLKRNGLTRVTVGM
>A0A4Y8U9K4|squalene-hopene cyclase|EC 5.4.99.17|[Brevibacterium] frigoritolerans|TrEMBL
MNQPVQSEINRLVHRLKQDQSADGSWNYPFDTGITADAYMIILLKILDMEDTPLIEALVK
RIESKQTENGSWKLFQDEKDGNVTVTIEAYYGLLFSGLRNKNHPHMRKAKQFILSKGGIK
QAKMLTKMMLTVTGQYQWPRIFPIPLEVVLLPPTFFVSIYDLSVYGRVNMIPLLLLGHKK
FQITTPDTPSLKDLFQTREDSSEEQVWEEYRTEEYRSFFSKLQTGVKTLIGYPDYLHSLA
LDSTKRFMLDRLEPDGTLYNYFGSTFFMIFALLSIGYSKRDPVILKAIAGLKGMACSIEG
HTHIQFTTPHVWNTSLISYALQEAGMPFKDKAVKAANQYLLSRQHYMYGDWLIHNPDAIP
GGWGFSDLNTINPDVDDTTASLRALAKQLQAKPDNRDSWQRGVAFTISMQNDDGGFPAFE
RNNDHKWLQLLPIEGSKYLLTDPSTADLTGRTLEFLGNYINMKKPEEVSKRAVDWLLEDQ
KRDGSWYGRWGICYLYGTWSALTGMKAAGQATGHPSIQKALTWLKKIQNEDGGWGESCYS
DIKQRYIPLGTSTLTHTAWAVDALISASEKPTAEIEKGIAYLIRAGQQESWTNDYPAGQG
MADFLYIHYHSYRYIYPLLALSHYNKKFLET
>A0A3N8KL73|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp8963|TrEMBL
MNNPIFPPWSALDAAIARGRDALAHLQQPDGSWCFELESDATITAEYILMMHFMDKIDDA
RQEKMARYLRSIQRLDTHGAWDLYVDGDPDVSCSVKAYFALKAAGDPEHAPHMVRARDAI
LKLGGAARSNVFTRILLATFGQVPWRAAPFMPVEFVLFPKWVPISMYKVAYWARTTMVPL
LVLCSLKARASNPRNISIGELFVTPPDEERHYFPPARGMRKLFLALDRTVRHIEPLLPKR
LRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMAVLSYPDDHPLRRDCEDALEKLL
VTRADGSVYCQPCLSPVWDTAWSTMALEQARGVAAPDSSANAHATRELDERIARAYDWLA
TRQVNDLRGDWTENAHPDTQPGGWAFQYANPYYPDIDDSAVVTAMLDRRGRTHRHADGTH
PYAQRVARALDWMRGLQSRNGGFAAFDADCDRLYLNAIPFADHGALLDPPTEDVSGRVLL
CFGVTKRADDRAALAQCIEYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALSGEDKSQP
YIARALDWLRAQQHPDGGWGETNDSYVDPHLAATNYGESTSNCTAWALLAQMAFGDWESE
SVRRGIAYLLSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLAGARS
LSDGRNPDTVAAADPAIA
>A0A7W7Z841|squalene-hopene cyclase|EC 5.4.99.17|Rhodopseudomonas rhenobacensis|TrEMBL
MHTDAPRNIDGALHATVEQAADWLIGRQKHDGHWVGRVETNACLEAQWCLALWFLGLEDH
PLRVRLGRALLDTQRPDGAWHVFHDAPHGDINATVEAYAALRSLGHRDDEEPLRKARDWI
IAKGGLRSIRVFTRYWLALIGEWPWEKTPNIPPEVIWLPTWFPFSIYNFAQWARATLMPI
AVLSAHRPSRPLPPQSRLDALFPDGRDGFNYDLPARFGAGLWDAFFRKADVVLHALQGWG
ARRGGPGWLRRGALNHVVEWIVRHQDHDGGWGGIQPPWIYGLMALHREGYAFDHPVMAKA
LDALNDPGWRVDVGEATYIQATNSPVWDTILALMALDDAGLARRYPAQIDSAVRWVLQRQ
VRVPGDWSVKLPGVEPGGWAFEYANNFYPDTDDTAVALIALAPFRGDPKWQAEGIDAAIQ
RGVDWLVAMQCRQGGWGAFDKDNNQKILAKIPFCDFGEALDPPSADVTAHILEAFAKLGI
ERSHPSVVRGLAFLKREQEPEGPWFGRWGVNYVYGTGAVLPALAAIGEDMRQPYIMRACD
WLVARQQDNGGWGESCGSYMDANLAGRGAATASQTAWALMGLLAANREQDRDAIERGVLY
LADSQREGTWQEAHYTGTGFPGYGVGQTIKLNDPLLSKRLMQGPELSRSFMLRYDLYRQY
FPLMALGRLLQQRGSTAARGD
>A0A841AA26|squalene-hopene cyclase|EC 5.4.99.17|Methylorubrum rhodesianum|TrEMBL
MREAAASKVETLQRPKTRDVSLDDVERGVQSATRALTDMTQADGHICFELEADATIPSEY
ILFHHFRGTEPRPGLEAKIGNYLRRTQSKAHGGWALVHDGPFDMSASVKAYFALKMIGDD
IEAPHMRAVRKAILQRGGAANANVFTRILLALYGEVPWTAVPVMPVEVMHLPKWFPFHLD
KVSYWARCTMVPLFVIQAKKPRAKNPRGVGVAELFVTPPESVRVWPGSPHATWPWTPIFG
AIDRVLQKTQDHFPKVPRQRAIDKAVAWVSERLNGEDGLGAIFPSMVNSVLMYEVLGYPP
DHPQVKIALEAIEKLVAEKDDEAYVQPCLSPVWDTALTSHAMLEAGGDRAEANARAGLDW
LKPLQILDIKGDWAETKPNVRPGGWAFQYANPHYPDLDDTAVVVMAMDRAQRQHGLVSGM
PDYSASIARAREWVEGLQSADGGWAAFDADNNHHYLNHIPFSDHGALLDPPTADVTARVV
SMLSQLGETRETSRALDRGVTYLLNDQEKDGSWYGRWGMNFIYGTWSVLCALNAAGVDPQ
SPEIRKAVAWLIRIQNPDGGWGEDASSYKLNPEFEPGYSTASQTAWALLALMAVGEVDDP
AVARGVNYLLRTQGQDGLWSEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKKGNS
RQVQFGM
>A0A537T3C4|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MSSLMHSADDLVGTRAGEALEASIASATRALLGSRQADGHWVFELEADSTIPAEYVLLSH
YLGEPADTALEAKIANYLRRVQGVHGGWPLVHDGDFDMSASVKSYFALKMIGDSPDAAHM
VRAREAILSRGGAIHSNVFTRFMLAMFGVMSWRSVPVLPVEIMLLPRWAPFHVSKISYWA
RTTMVPLMVLAALKPRAKNVSGTGIDELFLQEPHSIGMTAKAPHQSWGWFLLFRGLDSVL
RVIEPSFPNQLRARAIDAAVAFIEERLNGEDGVGAIFPPMANTVMMYEVLGKPADYPPRA
LTRRALEKLLVVTEHEAYCQPCVSPVWDTSLTCHAMLEAGNEALPAAKQGLDWLKPRQVL
DLKGDWAVKRPGLRPGGWAFQYNNDYYPDLDDTAVVVMAMDRARRASRSQEYDAAIARAQ
EWIEGMQSRNGGWAAFDVDNLEYYLNNIPFSDHGALLDPPTEDVTARCVSMLAQLGATIP
SSKALADGVAYLRRTQLAEGSWYGRWGLNYIYGTWSALCALNAAGVDHQDPVIRKAAAWL
LSTQNDDGGWGEDARSYRLDYSGYETAPTTASQTAWALLGLMAAGEVGHPAVARGVEYLI
ATQTQKGLWDEQRFTATGFPRVFYLRYHGYAKFFPLWALARYRNLRSTNTRVVGVGM
>A0A7W7YC43|squalene-hopene cyclase|EC 5.4.99.17|Prosthecobacter vanneervenii|TrEMBL
MKIPAFILTLALGTTAAFPQAATQPARNESLKQELRLSVERGINFLRSKQNPATGQWGES
EPVAMTALGIIGFMLDPNRKPGDPVPAEVEKATKYLISQARPDGGIFTKARGNYNTAMAL
TALLMNNKPENEEVMLKARRYLVRCQVDLDEKGKQDNPLDGGVGYGDEKGMHADLSNMTF
ALEALYYSQSMLADKGDAAKNEPQLNISAAIDFIQRCQNRPESNKSSWVSKDPDDAGGFI
YNPSETRGAKVTNPDGSVALRSYGSISYAGLLSFIYAGLDKDDPRVKAVIEWLQNHYNPD
ENPGLGAAGLYYYYQTMSKALSIAKIDFIKTKDGKLIDWRKDITEKLLSLQKGDGSWANA
EGRWMESDPVLVTSYILMALGRIHQTL
>A0A0K2B2F4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces ambofaciens (strain ATCC 23877 / 3486 / DSM 40053 / JCM 4204 / NBRC 12836 / NRRL B-2516)|TrEMBL
MTATTDGSTGATLKPLAAAASETDDITIPPAAAGVPEAAARATRRATDFLLSLQDAQGWW
KGDLETNVTMDAEDLLLRQFLGILDEETARAAALFVRGEQREDGTWATFYDGPGDLSATI
EAYVALRLAGDAPDTPHMAKAAEWIRSRGGIAAARVFTRIWLALFGWWKWDDLPELPPEL
IYFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPAVPNPPRPLAPA
ASWDGAFQRLDRALHAYRRVAPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVIA
LYLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLAVIALADAGVPADH
PQLVKAADWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRH
HDPERVERAIGRGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVTA
HVVEMLAVEGLTHDPRTRRGIQWLLAEQEADGSWFGRWGVNYVYGTGSVVPALTAAGLPA
SHPAVRRAVTWLESVQNDDGGWGEDLRSYRYVREWSGRGASTASQTAWALMALLAAGERE
SKAVERGIAWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPF
AEKHGVGNAAARAEQPAAQTSPAEVKGS
>A0A4Y9S4Y7|squalene-hopene cyclase|EC 5.4.99.17|Duganella callida|TrEMBL
MAPQTQLQPQPEARGAEAALEQAVNAILAHQRDDGHWLYELEADSTITAEYVLMVHYLGE
APNPQLEARLGRYLRRVQGADGGWPLFAHGEADVSASVKAYFALRMLGDPPDAEHMQRAR
ARILALGGAENCNVFTRTLLALYGILPWRCVPMMPVELMLLPMWAPFHVTKVSYWSRTVM
VPLLVLNSIRPQAINPLGVRIPELFKQPPHTHGLPPCAPHQNLLLYTVFMGLDCMLRVGE
MFVPRWLRGRALAQAERFVRERVNGEHGLGAIFPAMVNAVLMFNALGVPASDPDARLARE
SIEKLLVVGEEEAYCQPCVSPVWDTALACHAMLEAGGQRATAAAARGLNWLRRLQVLDLR
GDWAVRRPNLRPGGWAFQYENAYYPDVDDTAVVAMALDRYRRAEDDNLPSADASLLPLGE
AVERAREWVVGMQCANGGWGAFEADNTYHYLNNIPFADHGALLDPPTADVSARCLSLLAQ
LEGGVTSAAAQQALDYLLREQETNGSWFGRWGTNYIYGTWTALCALTAAGLGNDHLAVRR
AVEWLRSIQNADGGWGEDGDSYRIDYNGHMPAPSTPSQTAWALLALMAAGDSGSDAVTRG
IAYIVDTQQDDGGWIEEHFTAVGFPRVFYLRYHGYSQYFLMWALARYCNMRRDGAAAIQW
GM
>F4D0Z8|squalene-hopene cyclase|EC 5.4.99.17|Pseudonocardia dioxanivorans (strain ATCC 55486 / DSM 44775 / JCM 13855 / CB1190)|TrEMBL
MTLTAPELLATRTPRAALDAAVAFLRAGRHPDGWWQGELETNVTMDAEDLLLREFLGIRT
ETETAEAARWIRSRQRADGTWATFQDGPPDLSTTVEAWVALRLAGDDPAAEHMRRAQHHV
LAHGGLERTRVFTRIWLALFGLWSWDELPDMPPELIFLPKWFPLNVYDWACWARQTVVPL
TVVATLRPSRPLPFGVDELRTGAVPPPPARPWTWAGAFQRLDRVLHAYSRRPLRGLRRLA
MRRAAEWVLARQEADGSWGGIQPPWVYSLLALHLLGYPLDHPAVAAGLRGLDRFLVREDT
PDGVVRRLEACQSPVWDTCLAVTALLDAGVPADDPDVLAAADWLLAEEVRDVRGDWAVRR
PDIPTGGWAFEFDNDGYPDTDDSAEVVLALRRVAHPDPARLRAAVDRGVAWTVGMQSSDG
GWGAFDADNTRELITKLPFCDFGAVIDPPSADVTAHVVEMMAAEGLAGTDACRRGVDWLL
AAQEPDGSWFGRWGANHVYGTGGVVPALVAAGVSPTAPSIRRAVAWLERHQNDDGGWGED
LRSYDDPAWIGKGASTPSQTAWALLALLAAGERDSAATARGVRYLVDTQLPDGSWEETLY
TGTGFPGAFYIRYHLYRMVFPVSALGRYVHGEGTR
>G3IVQ6|squalene-hopene cyclase|EC 5.4.99.17|Methylobacter tundripaludum (strain ATCC BAA-1195 / DSM 17260 / SV96)|TrEMBL
MRTEISSLTSLDSAYTGSSYSPSTLDSAIDRAKAQLIRRQSQEGYWVFELEADCTIPSEY
ILMMHYMDEIDGALQAKIANFLRTQQSTDGSYPLYKGGAGDISCTIKVYYAMKMAGDSIQ
AVHMVKARDWILAQGGGARANVFTRIMLAMFEQIPWRGVPFMPVEIMLLPKWFPFHLDKV
SYWSRTVMVPLFILCTYKVKARNPLKIGVAELFVTPPDKERNYFSHVKTPLGKAILVVER
MGRLMEPLIPGFVRRKATAKARDWFMERLNGYDGLGAIFTAMVNAYEAMDYLGIPPDNEQ
RRIARAAIDRLLVINEDMAYCQPCVSPIWDTGLVALVLQEVDRHERDPHTRQALKSALSW
LAGKQLKDEPGDWRIRRPNLPGGGWAFQFGNSYYPDVDDTAVVALALIQADDQAFAENID
RAGIWIAGMQSSNGGYGAFDADNTHYYLNHIPFADHGALLDPPTVDVSGRCIMFLGKLVN
QHPEYRAVIDNCIDYLRNEQETDGCWFGRWGTNYIYGTWSVLIGFESAGVAKQDPSIRKA
VVWLKSKQRGDGGWGEGNYSYHNDKIRGEFDVSTAFQTALALLALLSAGELGCPEVEAGV
NYLLKSQQADGFWKDESFNAPGFPKVFYLKYHGYDKFFPLWALGRYRNELWVSA
>A0A7Y7NCH7|squalene-hopene cyclase|EC 5.4.99.17|Desulfuromonadales bacterium|TrEMBL
MNPCKYKISSSLTSLNAEAVEPVQFPARKARSKVHRLPPSIWKKMVAEGKSPLDKAIERT
RDFFFREQLPDGYWWAELESNVTITSEYIMLFHFLGMVDKERERKLANYILSKQTSEGFW
TLWYKGPGDLSTTIEAYFALKLAGYSADHAAMRKAREFILANGGIIKARVFTKIFLALFG
EFAWFGVPSMPIELMLLPDWAYFNMYEFSSWSRATIIPLSIVMSERPVRKLPPLARVQEL
FVRPPRPTDYTITREDGLLTWKNFFIGADHLIKIYESSPIRPFKKRAIATAEKWVLEHQE
QSGDWGGIQPAMLNSILALHCLGYANDHPAVAKGLEALANFCIEDEESIVLQSCVSPVWD
TALALVALQEADVPLDHPAMVKAAQWLLDLEVRRKGDWQVKSPELEPGGWAFEFLNDWYP
DVDDSGFVMLAIKDIKVRDKKHREQAIKRGIAWCLGMQSENGGWGAFDKDNTKYLLNKIP
FADLEALIDPPTSDLTGRMLELMGNFDYPKTYPAAERALEFLKREQEPEGPWWGRWGVNY
LYGTWSVLCGLEAIGEDMNQPYIRKAVNWIKSRQNNDGGWGELCESYFDRTLMGCGPSTA
SQTGWAILSLLAAGEADSKAAANGIKYLVDTQNEDGTWDEDAFTGTGFPKFFMIKYHIYR
NCFPLTALGKYRRLTTKKG
>A0A7H8M8M3|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. NAK00032|TrEMBL
MTTTEAPGLTGAAAAAVDAARGHLLGLQSPEGWWKAELETNVTMDAEDLLLRQFLGIRSE
AETKDAARWIRAQQREDGTWANFHGGPADLSTTIEAYIALRLAGDPVDADHMRRAAKFAR
DAGGIEGSRVFTRIWLALFGQWSWDDLPVMPPELMFLPSRVPLNVYDWACWARQTIVPLT
ILGSLRPVRDLPLDLAELRAGTMPAKKEKGWGRAFNALDRVLHVYEKRPVRPLRTAAMRR
AADWIIARQEADGCWGGIQPPWVYSLMALNVLGYDLDHPVIKRGLDGLERFTIRDEKGRR
LEACQSPVWDTVLAMNALGDAGAAPDDPALVRAAHWVLGEEVRGPGDWSVRRPGLPPGGW
AFEFDNDVYPDTDDTAEAILALRRTSLPEADAPIERAVRWLNGMASRDGGYGAFDADNTR
ELCTKLPFCDFGAVIDPPSADVTAHVVEALAKEGLAETAVAKRAVVWLLKAQEEDGSWFG
RWGANHVYGTGGVVPALIAAGVRPEKPAIRRAVAWLEQHQNEDGGWGEDLRSYDDPSWIG
RGESTPSQTAWALLALLAAGERSAAVDAGVRWLVENQRPDGNWDEDNFTGTGFPGDFYIN
YHLYRLVFPISALGRYLDGSS
>A0A8J7I0W8|squalene-hopene cyclase|EC 5.4.99.17|Amazonocrinis nigriterrae CENA67|TrEMBL
MQTQEREKVNKVAAAIASSQQYLLSMQNPAGYWWAELESNATITAEVVLLHKIWGTDQTR
PLHKVEAYLRQEQRQHGGWELFYGDGGELSTSVEAYMALKLLGVPATDPAMIRARSFILQ
RGGISKTRIFTKLHLALIGCYDWRGIPSLPPWVMLLPPTFPVNIYEMSSWARSSTVPLLI
VCDQKPVFVTDPAITLDELYAEGVDQVSYELPRNGDWTDLFLTLDQGFKLAESWNLVPFR
EEGIKAAEKWILERQEATGDWGGIIPAMLNSMLALRCLGYDTNDPIVERGLQAIDNFAIE
TESSYRVQPCVSPVWDTAWVIRALVESGFAPDYPAVVKAGEWLLQKQILDYGDWNIKNTL
GKPGAWAFEFDNRFYPDVDDSAVVVMALHLAKLPNEKLKQIACDRALNWIASMQCKPGGW
AAFDLDNDQDWLNSIPYGDLKAMIDPNTADVTARVLEMLGACNLAIDAKNLERALTYLIN
EQESEGCWFGRWGVNYIYGTSGVLSALALIAPQKYQLNIERGAAWLIGCQKPDGGWGETC
RSYDDPSLKGKGNSTASQTAWALIGLMAAGEATGKFAHEAIERGINYLVATQKPDGSWFE
ADFTGTGFPCHFYLKYHMYQQYFPLLALGRYQAVIKEA
>A0A7T0JQL8|squalene-hopene cyclase|EC 5.4.99.17|Methylomonas sp. LL1|TrEMBL
MLTETSSLSGSDSGHPDSCYSSSSLDRAIALAKIRLLGLQNHDGYWVFELEADCTIPAEY
ILMMHYMAEIDKPLQAKIANFLRGKQSDDGGYPLYTGGEGDISCTIKAYYAMKLAGDSPD
AAHMRRARVWILARGGAAKANVFTRIMLAMFEQVPWRATPFIPVEIMLLPNWFPFHIDKV
SYWSRTVMVPLSILCSYKVKARNPLKIGIAELFVIPAERETEYFSHVKTRLGKAILVLDR
IGRLMEPLIPAFVRRKATAKAQDWFMARLNAYDGLGAIFTAMVNAYEAMDYLGLPADNQQ
RQIARAAIDGLLVVKDDQAYCQPCVSPIWDTGLAVLALQEVDRYDHDRKSQYAVKTALRW
LAARQLSDEPGDWRVQRPGLAGGGWAFQFGNSYYPDVDDTAVVAYAMMQADTPEFADNIQ
RAAGWIAGMQSADGGYGAFDADNTHYYLNQIPFADHGALLDPPTADVSGRCVMLLGKLGL
RQLEYSDVVDSCVAYLRKQQESDGCWFGRWGSNYIYGTWSVLSGFENAGIDRHDPAIRKA
VVWLKSKQRIDGGWGEGNAGYHDSSIRGEFDSSSAFHTSLALLALLSAGENGCPEVESGV
AYLLKTQRADGFWRDDGFNAPGFPKFFYLKYHGYDKFFPLWALGRYRNESER
>A0A7Y3TMM8|squalene-hopene cyclase|EC 5.4.99.17|Flavobacterium sp. CLA17|TrEMBL
MQTQDQVSQSNISLEKLNQVIDRSQNYLLALQAAEGYWWAELESNVTMASEVVLLHKIWG
TNATRPLHKVENYLRRQQRDHGGWELFYGDRGELSTSVEAYMAMRLLGVPASDPALQRAR
KFICDRGGISKTRIFTKFHLALIGCYDWSGLPSLPPWLMLLPDSFPIYEMSSWARGSTVP
LLIVFDRKPVYRVDPAINLDELYAEGREYAKFELPSKGDWSDVFLWLDQAFKLGEALNLV
PFRDEGIAAAEKWVLERQEPTGDWGGIIPAMLNSLLALRALGYDANDPAVVRGMQSVDRF
AIETDDCYWMQPCVSPVWDTALVIRALVDSGIAPDHPALVKSAQWLLDNQILDDGDWTVK
NKAGKPGGWAFEFINRFYPDVDDSAVVVMALNAVQMPNEPMKQQAIARCVQWIATMQCNG
GGWAAFDLNNDADWLNQVPYGDLKAMIDPNTADVTARVLEMAGRLDKAQIPTSLSQTAID
RAITYLRHEQEPEGGWFGRWGVNYIYGTGGVLSALSLLATNSCHQEIDRGANWLVTCQNQ
DGGWGETCFSYNDRSLMGQGDSTASQTAWALTGLLAAGDATGTYAMAAIERGVQYLLDTQ
RSDGTWDEDYFTGTGFPGHFYLKYHLYLQHFPLTAIGRYRATALRLGGLSQED
>A0A5C8WG49|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium sp. WL6|TrEMBL
MREAVNKVEALQRPKTQAISLDDVDHGVARATRALTALAQADGHICFELEADATIPSEYI
LFHQFRDTRPPEGLEPKIGNYLRRTQEKHGGWALVHEGPFDMSCTVKAYFALKMIGDDIE
APHMRRAREAILSRGGAAQSNVFTRFILALYGEVPWSAVPVMPVEVMFLPKWFPFHLDKV
SYWARCVMVPLFVLQATKPRAKNPRGVGIGELFLTPPSSVRRWPGSPHATWPWTPIFGAI
DRVLQKVEAYFPHRIRLRAMEKARAWVSERLNGEDGLGAIFPAMVNTVLMYEAMGYGPDH
PQVRVACDAIEKLVVVKAHEAYVQPCVSPVWDTALAGHALLEAGGTDAEGQARAGLDWLL
PRQVLDIAGDWAAAKPKVRPGGWAFQYANAHYPDLDDTAVVVMAMDRAMRQHGLVANMPD
YTASIARAREWVEGLQSKDGGWAAFDADNNHMYLNHIPFSDHGALLDPPTADVTARVVSM
LSQLGETRESSKALDRGVTYLLNDQEQDGSWYGRWGMNFIYGTWSVLCALNAAGVDPASP
EIRRAVEWLIRIQNPDGGWGEDASSYKIDPAFEAGSSTASQTAWALLALMAAGECDDPAV
TRGINFLARTQGTDGFWNEERYTATGFPRVFYLRYHGYPKFFPLWAMARYRNLKRGNSRR
VAFGM
>A0A3B0RJ73|squalene-hopene cyclase|EC 5.4.99.17|hydrothermal vent metagenome|TrEMBL
MTDLPELPALIDQARANAKNAADHLMARQQDDGHIVFELEADATIPAEYIFLNHFLDDLE
PDLEAEMGDYLRSVQSDVHGGWPLFHDGDFNISASVKAYYALKIIGDDIEADHMVRARKA
ILDFGGAEKANVFTRYALALFGQVPWRAVPAMPVELMLMPRWFPVNIWKFSYWSRTVIAP
LLILASKRPVAQNPRGVNCSEIFKTPVEKIKVWNVNPTGSRWGDFFIALDKLLQPLAKHV
LPRLPFRQWAINRAIDFINPRLNGFEGLGAIFPAMANATMAFSVLGYDKDHPDYKVALGS
VRKLVVATADKRQGRARYCQPCVSPIWDTSLAAHSLLEAGVERTDKRVIAACDWLAKEQI
LDVKGDWAINAPDLRPGGWAFQYKNDYYPDVDDTAVVGMLLHRVDPEKYSENIARAAEWV
EGMQSSNGGWGSFDIDNNADFLNSIPFADHGALLDPPTVDVAARCISFLAQIGYDKDHPT
ITRGIDYLKSEQEEDGSWFGRWGTNYIYGTWSALCAINAVGEDMQSPWVRRAVNWLKSRQ
REDGGWGEDGATYWDDRKAEVKTSTPSQTAWALLGLMAAGEVDEEAVDKGIAYINTQPRD
GDKWDEEAYTAVGFPRVFYLRYHGYSAFFPTWALGRYANLKRGNSRQVEWGM
>A0A5E8VJW4|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. LVM 105|TrEMBL
MDSVNATSREALQQEALQPGTLQPGILESSIASATQGVLELQQADGHWVFELEADCTIPA
EYVLLRHYLAEPVDAVLEAKIANYLRRIQGAHGGWPLVHDGEFDMSASVKAYFALKMIGD
SVDAPHMVRAREAIHARGGAIHSNVFTRFLLAMYGVVTWRAVPVLPIEIVLLPFWSPFHL
NKISYWARTTMVPLMVLAALKPRAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFLLF
RSLDAILRVIEPLFPKSLRKRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKD
ENYPPRAVTRRGIDKLLVIGEEEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLD
WLIPRQELELKGDWAVKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGATGY
DTAIARGREWIEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISML
AQLGETAKTSKHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDHKDPM
IRRAAAWLASIQNKDGGWGEDAVSYRLDYKGWEAAPSTASQTAWALLALMAAGEVDHPAV
ARGVEYLIATQNKKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRV
VGVGM
>A0A7X7T191|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter sp|TrEMBL
MAADGSALSESRLSSEALDRAVLSAHTALSQAQQDDGHWVYELEADATIPAEYILLEHFM
DRIDDALEQKIAIYLRRIQSEEHGGWPLYHNGKFDLSATVKAYFALKAVGDDINAPHMQR
AREAILDHGGAERSNVFTRSQLALFGEVPWRATPVMPVELMLLPAKAFFSVWNMSYWSRT
VIAPLLVLAALRPVAANPRQIHVRELFVTPPEKVQDWIRGPYRSAWGYVFKGLDSVLRPV
VPFIPEKTHKKAIQAALDFIEPRLNGKDGLGAIYPAMANVVMMYRAMGVPDEDPRAKTAW
EAVQALIVEKDDEAYCQPCVSPIWDTGLSGHAMIEAASGPDGIAPEKTLSKLKTACAWLR
SKQILNVKGDWAVRNPNLAPGGWAFQYGNDYYPDVDDTAVVGMLLHREGDPANAESIERA
RTWIVGMQSTDGGWGAFDIDNNKDVLNHIPFADHGALLDPPTADVTARCISFLAQLRNPE
DEPVIQRGLEYLRKEQEKDGSWFGRWGTNYIYGTWSALCALNAAGVSHDDPAVVKAVEWL
RSVQRADGGWGEGCESYEGGPHGTYGESLPSQTAWAVLGLMAAGRRDDPAVARGISWLAD
QQDANGEWHEDPYNAVGFPKVFYLRYHGYKQFFPLMALARYRNLENSNSRRVSFGF
>A0A417YD88|squalene-hopene cyclase|EC 5.4.99.17|Oceanobacillus profundus|TrEMBL
MKSQITDEINRIIEVLKNDQSSDGSWDYPFETGVSTDAYMIILLRTLEINDEKLIQALVE
RILSRQEKNGSWKLFYDEKNGNLTATVEAYYALLYSGYRNKNDKELEDARRCILAWGGIE
KSHMLAKIMLALTGQYKWPSFFPMPVEFILLPLSFPINFFDFSVYGRTNIAPILILADQK
FVMKTNRSPDLSDLFLSRGNAENDEFFLNRSGDWRSFYSFIEQGIKNILGFPEYIHNMAI
QQTKKYMLDRIESDGTFYNYFSSTFLMIFSLLALRFPKNDPIIKKAVEGLKGMACQIDGK
THMQYTTANVWNTSLISYALQGAGIAWDDPMIGQANNYLLSHQQYRYGDWAIHNPTKTPG
GWGFSDKNTLNPDIDDTTASLRSITDLVQHEVVYRQAWDRGINWIFSMQNYDGGWAAFEK
NVDKKIVKLIPIEGAEYLLTDPSSADLTGRTLEFFGNFTNLSKNHNAIKNGVNWLRNNQE
KNGSWYGRWGICYIYGTWAAITGLISTGVDTENSSVQRSLKWLISIQNQDGGWGESCYSD
INQSYTPLGVSTLIHTAWALDTLIAASDNVTPEILAGVKFLLDTSNKKGWTLSYPAGQGM
AGGFYIHYHSYQYIFPLLALSHYRNKFLE
>A0A838X0B3|squalene-hopene cyclase|EC 5.4.99.17|Brevibacillus halotolerans|TrEMBL
MKEKAELEIKRIIHLLQKAQSVDGAWRYCLESGPLTDAYMIILLRTLMIDDEELIRSLAD
RITIRQEKNGAWKLFHDEEEGNLSATIEAYYALLFSGYSQKTDGHMQLAKKFILTKGGIS
EASMLTKLLLALTGQYPWSGYFQIPVEIILLPHWLPINFFDFVGYARVHIATILVVADRK
FVMKTRRTPDMSDLRKNDLPTALGNHPYLTNQRSHQYRAFLNTILDGFKNLPYLPSQIHN
TALRQAERYILERIEPDGTLYSYFTSTFLMIFALLSLGYSANHPVITRAISGLKAMTCLT
NGHLHIQIATSTVWNTALLAHAMQGTGVSASEPTIQNASRYLLSRQHHKYGDWMMKNPFV
LPGGWGFSDINTINPDVDDTTAALRAISKLRETDPTFHHSWDRGLNWLLSMQNADGGWPA
FEKNTDKRIGNWLPFDAADAVSTDPSTADLTGRTLEFLGNNAGFTIGHPQIQKGVKWLLS
NQEANGSWYGRWGISYIYGTWAAITGLMAVGVSSEHPAIQKAVQWLLKIQNEDGGWGESC
KSDIVKTYVSLGASTPSQTAWGVDALISVFQKPIPAIERGIQFLIDSEKNQDWTLSYPTG
GGLPGGFYFHYHSYQYIWPLLALGNYKKKY
>A0A536TVL8|squalene-hopene cyclase|EC 5.4.99.17|Betaproteobacteria bacterium|TrEMBL
MPGPEGVARHLRIADTESDLDRCIETATSALLRQQRQDGHWVFELEADATISAEYIALQH
FLGEFDTALEAKIATYLRRLQAPHGGWSLYHGGPFNISASVKAYFALKLVGDSPDAEHMR
RAREAILAHGGAGTTNVFTRILLALFGVVSWAAVPTIPVEIIFLPRWFPFHLSRISYWSR
TVLVPLLVLQAVKPRARNPRGIHIDELFPAERPAARRLAKAPHQSHARFALFAAVDALLR
LVEPLVPKRIRRRAIEKAVAFVTERLNGEDGLGAIFPAMANTVMMFDALRYPRDDPDFVT
ARKAIEKLLIFKRDEAYCQPCVSPVWDTALVCQSLLEVGGAQVLAAVHRGLAWLTDRQVR
ATIGDWADERLSVRPGGWAFQYANPHYPDLDDTAVVVMAMHRFVRPGTRDEAEFVEAIRR
GREWVLGLQSANGGWGAFDVNSTNEYLNHIPFADHGALLDPPTADVTARCVSMIAQLGDE
SDRAALTEAIEFLRRSQEVDGSWYGRWGMNYVYGTWSVLCALNAAGVSPRSPEVRRAVDW
LVFTQNADGGWGESGDSYALDYQGHEAAPSTASQTAWALLGLMAAGEVRHGAVTRGIDYL
LRSHEADGFWPELQFTATGFPRVFYLRYHGYAKFFPVWALARYRSMIHSSDPHIRFGM
>A0A552JJN8|squalene-hopene cyclase|EC 5.4.99.17|Microcystis wesenbergii Mw_QC_S_20081001_S30D|TrEMBL
MQIQDKITEIASKTAKAIELSQNYLLSTQYSDGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDLALEKAREFI
LAKGGISKTRIFTKMHLALIDCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKAVDNFAIE
TDNTYCVQPCVSPVWDTAWVIRALIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKSVMKRAVNWMATMQCKAGGW
GAFDMDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A6N6PJ29|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia bacterium|TrEMBL
MTLTSPTKIDRDPLAQAISKAQENLLRLQHADGYWVGELFVDSTLCSDYVLFMHWADEID
PVLQEKCVAHIRRRQIADGGWNIYEGGPSEVNATVKGYFALKLAGHAPTQPWMQEARACV
LRLGGIPQMNTYSKLYLALLGQFPWKYLPTVPVEMIFMPEWFFFSIYKMSSWSRAMLIPL
AILNHHKPSRALSADKQLHELYPVGSEQDFLGLSRKGRRLSWPNFFLACDAVLKLLHKLP
WKPGRQTALASAEAWMTERMGEGSDGLGAIFPAMLNSLIALKTLGYKNDHPLYAKAQRDF
EGLFVDDPRDFRIQPCLSPVWDTAINLIALRESGVPAASEPIQNAARWLAAKEVRICGDW
FAMNRHREPSGWAFEFNNVYYPDTDDTMMVLMALRLTGADGDADAKQRFERALRWLLSFQ
CKDGGWAAFDKDVTQRWLEDVPFADHNAILDPTCSDLTGRVLELLGYIGFDRKSDVVDRA
ITFIRDTQEDDGSWYGRWGVNYIYGTWQVLCGLRAIGEDMRQPWIVRARDWLESCQNEDG
GWGETCASYDNPNLKGKGTSTASQTAWALMGLIAATDPSGHAALDTRAIRRGIAFLLERQ
SSDGSWPEPEVTGTGFPRVFYLRYDMYRHNWPLLALATYRAYRSGGGHEPSFYHA
>A0A6M4PGV3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. jing01|TrEMBL
MTATTDGSTGATLPSRAAAASDTTLTTPEAAGVQEAAARAARRATDFLLSRQDSEGWWKG
DLETNVTMDAEDLLLRQFLGIQDEETTRAAAKFIRGEQREDGTWATFYGGPGELSTTIEA
YVALRLAGDAPDAPHMAKASAWVRERGGIAASRVFTRIWLALFGWWKWEDLPELPPELIW
FPTWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPARPNPARPLAPLAS
WDGAFQRIDKALHQFRKVAPRRLRKAAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLQHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALVDAGLPVDHPQ
LVKAADWMLGEEIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVALALRRVRHHD
PERVDKAIGRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAAEGLAHDPRTRRGIDWLLAEQEPNGSWFGRWGVNYIYGTGSVVPALTAAGLPGSH
PAIRRAVVWLESVQNDDGGWGEDLRSYKYVKEWSGRGASTASQTAWALMALLAAGEKDSK
AVERGIQWLAETQREDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFER
KLLARTKAAASRATGS
>A0A7V2WMQ9|squalene-hopene cyclase|EC 5.4.99.17|Hyphomicrobiales bacterium|TrEMBL
MARQQADGHIVFELEADATIPAEYIFLNHFLDDLEPELEAEMAAYLRSIQSDVHGGWPLF
HDGDFNISASVKAYYALKIVGDDISADHMVRARKAILDYGGAEKSNVFTRYALALFGQVP
WRAVPAMPVELMLMPRWFPVNIWKFSYWSRTVIGPLLILASQRPLAKNPRGVHCPEIFKT
PVEEIKVWNVNPTGTRWGDFFIALDKLLQPLEKHILPRLPFRKRAIRRALEFINPRLNGL
EGLGAIFPAMANATMAFNVLGYDREHPDYKIALASVRKLVVDTADKRKGKPQYCQPCVSP
IWDTSLSAHALLEAGVERTDERVIAACDWLAKEQILDVKGDWSVNVPDLRPGGWAFQYKN
DYYPDVDDTAVVGMLLHRVDSKKYAQNIARAAEWIEGMQSTNGGWGSFDIDNDAEFLNSI
PFADHGALLDPPTVDVAARCISFLAQVGYEKDHPTIKRGIAYLKSEQEEDGSWFGRWGTN
YIYGT
>A0A7W2BMH4|squalene-hopene cyclase|EC 5.4.99.17|Hyphomicrobiales bacterium|TrEMBL
MKFIPEFGQGSIMTIHFKDVDTVVHTQRAALLAEQKADGHFVFELEADTTIPSEYVLLRH
FLGEIDAPREEKIALYLRSHQNEDGSWPLFYGGAGNISASVKAYWALKLIGDDVDSEHMK
RGRDWILSQGGAATANVFTRIAMALFGQVPWRAVPVMPVQMMLQPVWSPFHISKMSYWAR
TVLVPLLVLFAKKAQGANPTGRNIRELFTVPPEQQKVYNVNHTGSAWGNAFLHLDKFLRK
LEPNALRAGKQTAIDKAVEFFTERLNGEDGLGAIYPAIANTVMAYHALGYPADHPDMVTA
RSAVEKLFTERGEEIYYQPCLSPVWDTCLAAHAILESGDRDEPKLKAALDWLKDRQILDV
KGDWAVRRPDVRPGGWAFQYENAYYPDVDDTAVVILAMSRQGSPDYAEAIERGCEWLLGM
QSSSGGWGAFEPENEHFYFNHIPFADHGALLDPPTVDVTARCVGALSQVDRVRYMKAIRK
GVDFIRREQEKDGSWYGRWGANYIYGTWSALVALKSAGEDMSQPYIQKAVVWLKAHQNSD
GGWGEGLETYDPTCKGYNEGSTASQTAWALMALMSADAVEDSAVRKGITYLTHAPKDGAR
WDEKYWSGTGFPRVFYLKYHGYAAYFPLWAMARYQGLMASNDRSVKWGI
>A0A848Y939|squalene-hopene cyclase|EC 5.4.99.17|Hyphomicrobiales bacterium|TrEMBL
MTSVYNPSGTGDVSSVSEVAREPANENLAAPSPYELDHIISETAGELEKLQHEDGHIVFE
LESDATIPSEYIFLNHFLGELEPDIEAEIAEYLRSLQSDRHGGWPLFHEGGFNISASVKA
YYALKLVGDDPEAAHMMRAREAILHNGGAETANVFCRYALALFGQVPWRAVPAMPAELML
MPKWFPVNMWKFSYWSRVVIAPLLIVAALKPKAANPNGVDCQELFCIAPNVIKKWHINPT
GTKWGEFFLGLDRVLQVVEPYFPKGRRARAIQAALDFIKPRLNGTDGLGAIFPAMANVVM
AFHALGMDPESEEYKTAREATRSHLTEAKVSPTTGATQRYCEPCKSPVWDTALAAHALAE
ADQFGDKPKALISACDWLAKLQVRDVKGDWSVNAPGVEPGGWAFQYANDHYPDVDDTAVV
GMLLHRADPQRYAKEISRAVSWIEGMQSSNGGWGAFDIDNNADFLNSIPFADHGALLDPP
TADVTARCLSFLAQVGHELDLPVIKRAIAFLKAEQEEDGSWFGRWGTNYVYGTWSVLCAL
NAANEDMKAPYVQKAVRWLLAHQRKDGGWGEDGATYWQERRSEAKSSTPSQTSWAVLGLM
AAGETNHPAVARGISYLKDHPRENGRWDEPWYTAVGFPRVFYLRYHGYSAFFPTWALARY
RNLKRANSGDVRWGM
>A0A6I5GA58|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8380|TrEMBL
MTATTDGSTGAATPPATTASAPLHLSPEASEAHEATARATRRAVDFLLDRQSDEGWWKGD
LATNVTMDAEDLLLRQFLGIRDEATTQAAALFIRGEQQEDGTWNTFYGGPGDLSATIEGY
VALRLAGDSPEAPHMRKAAAFVRARGGVARARVFTRIWLALFGWWKWEDLPEMPPELMFF
PKWAPLNIYDFGCWARQTIVPLTVVCAQRPVRPAPFALEELHTDPADPNPAQPAPPVASW
DNVFHKLDKMLHGYRKVAPRRVREAAMRAAATWIVERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVLRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATVALADAGVPADHPQM
IRAADWMLAEQIVRPGDWVVRRPDLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVAHPDA
TRVDKAVRRAVDWNAGMQSKNGAWGAFDADNTSPFPNRLPFSDFGEVIDPPSADVTAHVV
EMLAEEGLAHHPRTRRGIEWLLENQEANGSWFGRWGVNYVYGTGAVVPALVAAGIPAAHP
AIRRSVSWLGQVQNEDGGWGEDLRSYQDTAWHGRGHSTASQTAWALLALLAAGERDSEQV
RRGIAYLVETQTEDGTWDEPWFTGTGFPWDFTINYHLYRQVFPVTALGRYLNGTGPGEN
>A0A661VEE3|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MTHFMGKELSEGRKEGIIRFVRSRQNADGSWPAYHGGPGDLSVSVQVYFALKLAGVSAEK
PFMKKAREFILSKGGVGKANVITKFWLACFGEFPWDGTPTVPPELIFLPRWFYLNIYEFS
SWARATIMALALLSHLRPIRPVPEGRGVKELYLEGRQDCSLGQRKGFISWENLYLLMDRL
LKAYRKLPVKPGRGIALKRVERWVVEHQDADGSWGGIMLPWLYALFALKELGYHDDHPVL
KRGMEGLENFIVEDERGFRLQPAVSPVWDTAWVVIALRESGFPPDHPTLVQAARWLLRKH
IRVKGDWAVKNPHIEPGCWAFEFENNFYPDIDDSSVVPRALLRVKLPGQEEREKVEAIRR
AARWVAAMQSKDGGWAAFDKDNNKSPLAHIPFADFITPLDPTSPDITNHAIEFLSEVSGF
DENIRSGVEYLRKTQEADGAWFGRWGVNYIYGTGLVLPALRAVGEDMRSDYIRKAVSFLK
SLQNEDGGWGESCRSYDEPDLRGQGPSTPSQTAWALLGLLAAGEERSPTVSRGIEYLLRT
QQSDGRWDEEAFTGTGFPRAFYLRYHMYPIYFPLMALARFRSAIQARSDENDQANE
>A0A652LW18|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. or43|TrEMBL
MTATTDGSSGAVDPRAASASSPTTESTIAADDVLAAARRAAERSVEHLLGRQDEQGWWKG
DLATNVTMDAEDLLLRQFLGIQDPATVRAAGRFIRGEQLGDGTWATFHGGPGDLSATIEA
YVALRLAGDRPDEPHMARAAGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMF
FPKWVPLNIYDFGCWAXQTIVPLTVVSAKRPVRPAPFALDELHTDPDEPNPTRRPAPAAS
WDGIFQRLDKALHVYHRFAPRRLRRVAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLDHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVAADHPA
LVKAADWMLGEEIDRPGDWSVRRPQLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPE
PARIEAAIERGVRWNVGMQSRNGAWGAFDADNTSAFPNRLPFCDFGEVIDPPSADVTGHV
VEMLAIEGHSAHPATRRGIEWLLAEQDAAGGWFGRWGVNYVYGTGSVVPALVAAGLPASH
PSIRRAVGWLESVQNDDGGWGEDLRSYNEDKWIGHGASTASQTAWALLALLAAGRRDTVA
VSRGIAWLAETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFAGR
TAVREGA
>A0A6L9Q9V7|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura bangladeshensis|TrEMBL
MTTLETPETPAATAPRTAAEALEAARDHLLLLQSPQGWWKGELQTNVTMDAEDLLLREFL
GIRTDEDTGEAARWIRSQQAPDGTWANFHDGPPDLSTTVEAYVALRLAGDLPDAGHMIRA
AAYIRSEGGVPAARVFTRFWLAMFGRWSWDELPVVPPEMLFLPRWFPLNVYDFACWARQT
IVPLAVVGALRPVRPLPFGLDELVPDYDVPRPKKRELTGWGAAFGALDKALHVYQRHAAG
RRPLKGVRDAALRRAGEWIVARQERDGSWGGIQPPWVYSLLALHLLGYGLDHPVIRRGLD
GLERFTIRDERGRRLEACQSPVWDTVLAMNALADAGLNAGHPALERAAEWVIGEEVRGPG
DWSVRRPDLPPGGWSFEFDNDVYPDVDDTAEVVIALDRVRHPKAEPAIERGVRWMAGMVS
ADGGFGAFDADNTRTLCRKLPFCDFGEVIDPPSADVTAHVVEALAHRGMADSLLAKRAVV
WLLKAQEPDGSWFGRWGANHVYGTGAVVPALIAAGVRPEKPVIRHAVGWLARHQRDDGGW
GEDLRSYRDRSWVGHGTSTPSQTAWALLALLAAGERGPVVERGIRWLVEHQRPDGTWDED
HFTGTGFPGDFYINYHLYRLVFPLSALGRYLKGS
>A0A3N6N6M4|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. RP6|TrEMBL
MDSVNATSRETLESSIASATQGVLGFQQSDGHWVFELEADCTIPAEYILLRHYLAEPVDT
VLEAKIGNYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDSVDAPHMVHAREAIH
ARGGAINSNVFTRFLLATFGVVTWRAVPVLPIEIVLLPFWSPFHLNKISYWARTTMVPLM
VIAALKPRAKNPLGVGIDELFLQDPRSIGMTAKAPHQSMAWFLLFRSLDAILRVIEPLFP
KSLRKRAIDAALAFIEERLNGEDGMGAIYPPMANIVMMYDALGKDENYPPRATTRRGIEK
LLVIGDDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLDWLIPKQELEVKGDWA
VKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGATGYDTAIARGREWIAGMQ
SDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETEKTSKHVAD
GIAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDHKDPMIRKAADWLTSIQNQD
GGWGEDAVSYRLDYKGWEAAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIATQNKKG
LWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A0D0GDE1|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. MSHR3999|TrEMBL
MKPNHAFSPSALDAAILRGRDALSGLQQPDGSWCFELESDATITAEYILMMHFMDKIDEV
RQAQMARYLRAIQRVETHGAWDLYVDGAPDISCSVKAYFALKAAGDSEHAPHMIRAREAI
LKLGGAARSNVFTRILLATFGQVPWRAAPFMPVEFVLFPKWAPISMYKVAYWARTTMVPL
LVLCSLRARARNPRNVSIAELFVTPPDEERHYFPPAKGMRRLFLALDRTVRHLEPLLPRR
LRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMEVLGYPEDHPLRRDCEHALEKLL
VTRADGSVYCQPCLSPVWDTAWSTMALEQARGATPAAPDAQVSDRDLDARIARAYDWLAT
RQVNDLEGDWRENARPGTQPGGWAFQYANPYYPDIDDSAVVTAMLDRRGRAQARTSGENP
YAERVTRALDWMRGLQSRNGGFGAFDADCDRLYLNAIPFADHGALLDPPTEDVSGRVLLC
FGVTKRPADRAAAARAIEYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALSGEDKSQPY
IARALDWLRAHQHADGGWGETNDSYADPQLRATNYGESTSNCTAWALLAQMAFGDWQSDS
VRRGIAYLLSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLAGAQAA
PSAPGPGTAATIADPAVA
>A0A7X0L0C4|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura coerulea|TrEMBL
MTTTDVSGLTGAAAVAAEAARDRLIGLQSPGGWWKAELETNVTMDAEDLLLRQFLGIRSD
ADTKDAARWIRSRQRDDGTWANFHGGPADLSTTIEAYVALRFAGDPVDAGHMRRAAAYVR
EAGGIEGSRVFTRFWLALFGQWSWDHLPVMPPELMFLPSRVPLNVYDWACWARQTIVPLT
VLGSLRPVRALPFDLPELRCGVMPAKDARGWGAAFGALDRVLHVYERRPVRPLRRAALRR
AADWIIARQEADGCWGGIQPPWVYSLMALHELGYGLGHPVIRRGLDGLERFTIRDGKGRR
IEACQSPVWDTVLAMNALADAGAAADHPALLRAAEWVVGEEVRGPGDWAVKRPDVPPGGW
AFEFDNDVYPDTDDTAEAILALRRAAFPAAEEPIRRAVRWLEGMASRDGGFGAFDADNTR
ELCTKLPFCDFGAVIDPPSADVTAHVVEALSKEGLAESAVVRRGVVWLLRAQEADGSWFG
RWGANHVYGTGSVVPALVAAGVRPGKPAIRRAVVWLEDHQNPDGGWGEDLRSYDDPAWIG
RGESTPSQTAWALLALLAAGERTPAVDAGVRWLVDHQRPDGNWDEDQFTGTGFPGDFYIN
YHLYRLVFPLSALGRYLDGAA
>A0A3E0LCX3|squalene-hopene cyclase|EC 5.4.99.17|Microcystis flos-aquae DF17|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNNWSDVFLWLDGLFKWTEKTDLVPFR
QESLQAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVDDPIVARGLKAVDNFAIQ
RDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAIIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKGVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVKMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNQYRHQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A7C4G2E0|squalene-hopene cyclase|EC 5.4.99.17|Bryobacteraceae bacterium|TrEMBL
MTPAAQPALSAPALAEAVRRAGEALLGLQRPEGCWWADLTSDTTLESDAVLLALFLHPPV
GGVWNPPHRERIQRAAQSILARQLPDGGFCIYPEGPAEVSATVKAYVALKLAGVPLSDAR
MARAREAALSLGGVQAANSYVKLNLSLFGLYPREFVPTVPPEIAILPGGILHQMSSWTRA
IVVPLSVVQALGGVRPVPAGFHLDELFLPRAPLGFSRDPKLFSWPNAFLFLDRCLKLWER
YGAGAVRRRAVRRAEAWMLERAREADGLGAIYPPMMYFLMALDVLGYPPEHPVRVEAQRQ
FDRLLTDEDGRFFYQPCFSPVWDTGIAMQALGESGFAGSKPLRRAAAWLVEREIRRRGDW
SFKRPHLEPSGWCFEFRNDWYPDIDDTAQALLGLTASGAGVPQPVRQRAVAWLKGMQSSD
GGWAAFDADNDWQILNQVPFADHNAMLDPTCPDITGRTLEALAACGTPRSDPSVRRGVRY
LVKTQQPDGSWYGRWGVAYIYGTFLALRGLRAAGEDDREAHILRAAEWLRSIQNADGGWG
ESCAAYDEGCFVPARSTASQTAWAILGLAAGGDRSSSSVRKGVEYLIETQKEDGTWDESL
ATGTGFPRVFYLRYDLYRNAFPLLALNEIMKQQRGVNA
>A0A7V5YSV4|squalene-hopene cyclase|EC 5.4.99.17|Bryobacteraceae bacterium|TrEMBL
MQATPCSATARPAFELERAARRAIEWLLAQQQPEGFWVGFLQSNCCMEAEWILAMHFLGV
HDDPKLPGVIRTILREQRPDGSWQVYYGAPSGDINTTVECYAALRAAGLDPKSEALQKAR
QWILQHHALSQIRNFTRYWLALIGEWPWEETPALPPEIILQPDWSPFSIYRFASWARGTI
VPLAILSARRPVRPLPLERRLDELFPQGRGNFDFRLPRQHSWLSVEGLFYLADRFLNWYV
QFPWHPLREYAIRLCLEWIVRRQEADGAWAGIQPPWIYSLMALHTEGYALDHPVMRAGLD
AFNQHWKYEQDGAIYLQASESPVWDTLLSIIALLDCGPLPETLPALERAAEWILSKQIHA
WGDWKVYVRHARGGGWAFERANRFYPDVDDTAVAVLALARLKPHLRDPRPVDAALELATE
WILAMQSSNGGWAAFDKDNTTYLLTRIPFADFGELLDPPSVDVTAHVVEALGTLGWPKHH
PAIQRALRYIRQEQEPDGSWFGRWGVNHIYGTGAVLPALRAIGEDMRQPYVLKAADWLVA
HQNPDGGWGETPASYVNPALRGRGTSTASQTAWALLGLMAVDDPRYRPAIARGLAFLVER
QLESGTWDEPEYTGTGFPGYSVGERIDLATRSGQLRQGLELQRAFMINYHLYRHYFPLMA
IGRALRAGYTACL
>A0A7H1RZS0|squalene-hopene cyclase|EC 5.4.99.17|Geobacillus zalihae|TrEMBL
MVDDERRVLIDALKQSQAADGSWRFPFETGISTDAYMIILLRTLGIHDEPLIQALVERIE
SRQDPNGAWKLFADEGDGNVTATTEAYYALLYSGYRKKNDPHMQKAKARILEMGGLERVH
LFTKVMLALTGQHPWPRRFPLPLEFFLLPPSFPLNMYDLSVYGRANMIPLLVAAERRYSR
RTAKSPDLSDLVVSRNDWRLPESRSLWSYIKRSLIGLPDQLHHAAEQRAVRYMLDHIEPD
GTLYSYFSSTFLLIFALLALGYPKDDPYIQRAIRGLRSLRTEIDGHTHMQYTTASVWNTA
LASYALQEAGVPLTDRTIEKANRYLLSRQHIRYGDWAVHNPYGIPGGWGFSDVNTMNPDV
DDTTAALRAIRRAAAKETAFRHAWDRANQWLFSMQNDDGGFAAFEKNVGKRFWRYLPIEG
AEFLLMDPSTADLTGRTLEYFGTFARLTKDHPAVARAVDWLLDHQEADGSWYGRWGICYV
YGTWAAVTGLSAVGVPIDHPAMQKAVHWLLSIQNADGGWGESCKSDGAKTYVPLGASTPV
HTAWALDALIAAAERPTAEMKAGVRALIRLLRHPDWTASYPAGQGMAGAFYIHYHSYRYI
FPLLALAHYEQKFGPFVD
>A0A844MM15|squalene-hopene cyclase|EC 5.4.99.17|Scytonema sp. UIC 10036|TrEMBL
MQIQDKQTVSRIQKAIATSQNYLLSLQYPDGYWWAELESNVTITAEVVLLHKIWGTDSKR
PLHKVEAYLRAQQREHGGWELFCGDGGELSTSVEAYMALKLLGVSETDPTMVKARKFILQ
RGGISRTRIFTKLHLALIGCYDWLGIPSLPPWVMLLPSNFLFNIYEMSSWARSSTVPLLI
VFDRKPVFVTNPAISLDELYTEGVEQAKFELPRQGDWTDIFIMLDNAFKLAENLNLVPFR
EEGIQAAERWILERQEATGDWGGIIPAMLNSLLALRTLGYDAADPIIERGLQAVDNFVIE
TENTYTVQPCISPVWDTAWAMRSLVASGLAPDHPAVVRAGEWLLNKQILDYGDWSVKNRQ
GKPGAWAFEFDNCFYPDVDDTAVVVMALDVVKLPNEKLKQAAMTRAVNWIASMQCRAGGW
AAFDLDNDRDWINLIPYGDLKAMIDPNTADVTARVLEMLGGCNLFIDDDKLERAITYLLQ
EQEPEGCWFGRWGVNYIYGTSGVLAALSLIAPKRTQVRIEKGAAWLVGCQNTDGGWGETC
RSYDDPSLKGKGTSTASQTAWALLGLIAAGEATGKFARTAIQRGVHYLTETQKPDGTWYE
SEFTGTGFPSHFYLKYHLYQQVFPLLALSKYQDISHLL
>A0A3E0M2N1|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa DA14|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
KRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVDDPIVARGLKALDNFAIQ
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPSIIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKSVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYSDLKAMIDPNTADVTARVLEMLGTCDVKMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYQALI
>A0A840WGJ7|squalene-hopene cyclase|EC 5.4.99.17|Rubricella aquisinus|TrEMBL
MPPSQAALADGLSRAIGYVRARQRSDGAWSLPVRSDPRITAFTLATHAQLGRAATGQTRA
LERYLAATQKPDGTWEGWIGGGEALEVTAVCAMALEYATTTEGQHACQAASRWLETLPPP
RIDGFWLGYLAHHGDLRWDEIPHVSLRLLSVPRWMHPNIHDFGVLRLALVAMGVIQAVAM
PRPAPPVPKWRAPWLSAARAAFGGGAAALSRALRAADRLGGRGGRVEAALQWLLARQEAD
GSFFSSTHLTSAVLRALHEADPVRFAPEINAGFAALEGWQHAHADGRWQAFTDATIWDTA
LFTTLLQDHGAPEDRARIAHAQTYLLSQQIYHPGDYQARASYPAVGGWSFQHNTRMHPDV
DDTVLTLGVLMRADEPDLRALRDGVDWLLSMQGRDGGWASWDRDDRGWVRRLGGGRWFLS
DTACPVLTARAAGLLQRVAMGEVQGLSDLVPRAGDAARRALRFVDAAGPEGRWLCRWFTH
YIYGTAYGLGALMQHGRSDDPRIADALSWFERIAQPDGGFGEAPVSLIEGHYASAPSNPF
HTACVLRAFVAAGQGRHPVAHRAAQWLLQHQDAEGGWSCEMLYAAGIPGVWYTDFTSTPT
YEATQALQHYSTAQDC
>A0A0U5MDA4|squalene-hopene cyclase|EC 5.4.99.17|Magnetospirillum sp. XM-1|TrEMBL
MSPSEINPRDFTAASFRDPLERAINESAEALLKQQREDGHWVFKLEADATIPAEYVLYLH
YLDERDPELEKRIGVYLREIQEDHGGWPLFHRGDLNISASVKAYFALKAIGDDIDAPHMK
KAREAILAHGGAATANVFTRTLLALFGQIPWKGVPIMPVEIMLLPRWFPFHMDKVSYWSR
TVIAPLTVLMTKRPQARNPLGIHIQELFVTPPEKVTNWYLEPVRSNWAYLFRGIDMILQK
VYRFFPKSVQDKAIEKAVAFVDERLNGEDGLGAIFPAMVNAVWMYDVLGVPKDDPRVVIA
KQSIRNLVVEEGERAWVQPCLSPIWDTALATHAMLEVGTPEADAAVRKAADWMVARQITD
VVGDWAVRRPGLAPGGWAFQYNNPHYPDVDDTAVVMAALDRIDPVKYAEPIEKGKVWIQG
MQSEGGGWGAFDAENTSYYLNHIPFADHGALLDPPTADVSARCVSVLSVLGERGKDKVAH
EGVDYLLREQEADGSWFGRWGTNYVYGTWSSLCALNAAGLPHDHPAFRKAVKWLESKQRE
DGGWGECGRSYWDDQPRGMGGPSTPSQTAWAVLGLMAAGETNSPAVAKGIDYLIRTRNEE
GLWDEEHYTAVGFPRVFYLRYHGYRQFFPVWALARYRNLTTGNAGPVMHAL
>A0A0S4KTC5|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Nitrospira inopinata|TrEMBL
MNLIRSLISRLSEGLLSTSPGKLSHAMEPSPSPSLRLVSEKMTGLPSLEPATRRATGHAH
NQPDAIDDAIRRSQTWFLNRQHAEGYWVAELEADTTLTSEYIMLRRFLDRVDPDREEKAV
RYLKATQLPDGGWPIYYGGPSEISASVKAYFALKLTGVSAEEPFMVRAKERILAMGGVVH
ANVFTKIALALFDQYDWEGVPHMPVEIMLLPKKFYFNVYAISYWSRAVLIPLLIVFAYRP
VCRISHEQGIDELYPVPRRTIRYWKYPPFNKDQDWFTPHNFFVALDALLKVYDRMPLRAL
RRKALKRAADWMLEHMKGTGGLGAIYPAMANSIMALQCMGYDADDPLVVKALREIEELEV
YDSVELDGRSVPALHLQPCFSPIWDTALLINAMIESGMPQDHPALQKAAAYLMSRQAKKE
GDWIVSSPSAEPGGWYFQFENELYPDVDDSAVVLMGLAKLKMAQAAEQRESIRRGMKWVL
AMQGSDGGWGAYDKDNNRVVFNYIPFADHRALLDPSTSDLTGRCLEMLGTLGYDRTHPAV
GPALAFLKKEQEQDGSWYGRWGVNYIYGTWSVLAGLRAMGEDPSSPYIRRAVSWLESKQN
PDGGWGESCLSYADPAFSGKGESTPSQTAWALMGLMSAGVVDSFSVARGVQFLLRHQMKD
GSWEEVRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRARGKTRADELRLHVQAAGSH
RTEH
>T2AZV0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKTIMGKAANWPVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDRYSEAIARGAEWIIGMQSRSGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAVGYLKCGQEVNGSWYGRWG
>T2B088|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTADVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGRWG
>T2AY17|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIFMEKAANWLVKRQILDVIGDWGANVHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDCYSEAIARGAEWIIGMQSGNGGWGAFDVNNEHHFLQ
HIPFADHGALLDPPTADVSARCLFMMAQLGYGLDNQAVARAIGYLKRGQEVNGSW
>T2B094|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYFPDVDDTAVVVMALHRADPARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWFGRWG
>T2AZK2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAICSNALLDSGLPTDHPALVRAGKWVVSKQVTKRGDWQVKSPKAEPGGWAFEFY
NELYPDTDDTAEILLFLNRVEIPDNRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGKWGFNKQHPQVKRAIKFVKERQEIDGCWYGR
WG
>T2AZG2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PRVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPGLSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTKNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHSYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWFGSW
G
>T2B000|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALTMNALIESGIALNHPALDRADAWLRTRQSQKVGDWVVSSPEAKPGGWSFQYE
NDWYPDVDDTSAVITAMAKVHQAETPDFDEVLQRGFHWVLAMQGSDGGWGAYDKDNNKLI
FNKIPFADHQALLDPSTADLAGRCLEMLGTLGYDQSHPAVGPALEFLLKEQEANGSWYGR
WG
>T2AZJ0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHALLEANLALDKAIMQKAADWLVERQILDVIGDWGANARGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRVDPNRYSEAIERGAEWIIGMQSGNGGWGAFDKDNEHHFLQ
HIPFADHGALLDPPTADVSACCLSMLAQLGYGYEIEAVSRVVGYLKREQEHDGSWYGRWG
>T2AZH9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGRW
G
>A0A6B8LUG3|squalene-hopene cyclase|EC 5.4.99.17|Methylocystis rosea|TrEMBL
MNAAARIDANFAAVSTEALETSIQNAKRALLSLGKGDGHFCFELEADTSLSAEYVLMRHF
RAEPLDAELERKIGVYLRRCQGDHGGWPLYQDGPFHISSSVKAYFALKMIGDDVDAPHMA
RARAAILAYGGGAKSNVFTRALLALYGEIPWRGVPVMPVEIMLLPKWFPFHLDKISYWGR
TVLVPMLVLMTKKPRAKNPRNIHIAELFTTPPEEVKVWPKGEHQTWPWANIFGQLDKLLR
LIEPHMPSGPRERSIELAMTWTTERLNGVDGLGGIFPSMVNSLLMYDVLGVPDADERKKQ
AREAIERLLVVHDAEIYCQPCVSPVWDTCLTAHTLLETGDEDAREQARQACEWLAPLQVL
DVKGDWAAQRPHVRPGGWAFQYANAYYPDVDDTAVVVTAMDRLTANDASRPYDERIARAK
EWIIGMQSKNGGWGAFDADNTCHYLNHIPFADHGALLDPPTADVSARCVSMLAQLGDTID
SSECLKRGVDYLLKEQEKDGSWFGRWGANYIYGTWSTLCALNAVGLPHDHDAYRRAVAWL
VAIQNEDGGWGEDLASYKLDYKGYEKSPSTASQTAWALLGLMAAGDVDHPAVARGIAYLQ
STQNDAGLWNEARFTATGFPRVFYLRYHGYGKFFPLWALARYRNMRRANSKRVQVGL
>A0A1I3TLB6|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium brachiatum|TrEMBL
MREAVSKVEPLQRSKTQGISLDDVERGVAQATRSLINLAHDDGHICFELEADATIPSEYV
LFHHFRGTPVPDGLEAKIGNYLRRTQGRHGGWALVHEGPFDMSCTVKAYFALKMIGEDIE
APYMRRAREAILSRGGAANANVFTRFMLALYGEVPWRAVPVMPVEVMFLPKWFPFHLDKI
SYWARTTVVPLFVLQATKPRARNPRGISVQELFITPPESVRTWPGSPHATWPWTPIFGFI
DRMLQLVEDRLPRKSRQRAMEKARAWVSERLNGEDGLGAIFPAMVNSVLMYEVMGYRPDH
PQVRVACDAIEKLVVEKADEAYVQPCVSPVWDTALASHALLEAGGPEAEAQARAGLDWLK
PRQVLDIVGDWAARKPKVRPGGWAFQYANPHYPDLDDTAVVVMAMDRAMRQHGLVAGMPD
YKASIARAREWVEGLQSEDGGWAAFDADNNHMYLNHIPFSDHGALLDPPTADVTARVVGM
LAQLGETRETSRALDRGVNYLLNDQEEDGSWYGRWGMNFIYGTWSVLCALNAAGVDSADP
RIQRAVSWLIRIQNPDGGWGEDASSYKIDPAFEAGSSTASQTAWALLALMAAGAVDDPAV
TRGINFLTRTQGADGFWNEERYTATGFPRVFYLRYHGYPKFFPLWAMARYRNLKRTNSRR
VQFGM
>A0A8F6CVG4|squalene-hopene cyclase|EC 5.4.99.17|Methylococcus capsulatus|TrEMBL
MLREATAISNLEPPLTASYVESPLDAAIRQAKDRLLSLQHLEGYWVFELEADCTIPAEYI
LMMHFMDEIDAALQAKIANYLRSHQSADGSYPLFRGGAGDISCTVKVYYALKLAGDSIDA
PHMKKAREWILAQGGAARSNVFTRIMLAMFEQIPWRGIPFIPVEIMLLPKWFPFHLDKVS
YWSRTVMVPLFILCSHKVTARNPSRTHVRELFTVDPQKERHYFDHVKTPLGKAILALERF
GRMLEPLIPKAVRKKATQKAFDWFTARLNGVDGLGAIFPAMVNAYEALDFLGVPPDDERR
RLARESIDRLLVFQGDSVYCQPCVSPIWDTALTSLTLQEVARHTADLRLDAALSKGLKWL
ASKQIDKDAPGDWRVNRAGLEGGGWAFQFGNDYYPDVDDSAVVAHALLGSEDPSFDDNLR
RAANWIAGMQSRNGGFGAFDADNTYYYLNSIPFADHGALLDPPTADVSARCAMFLARWVN
RQPELRPVLERTIDYLRREQEADGSWFGRWGTNYIYGTWSVLLAYEAAGVPNDDPSVRRA
VAWLKSIQREDGGWGEDNFSYHDPSYRGRFHTSTAFQTGFALIALMAAGEAGSPEVQAGV
DYLLRQQRPDGFWNDECFTAPGFPRVFYLKYHGYDKFFPLWALARYRNERYALA
>A0A2L0X438|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus metallidurans|TrEMBL
MNQAATITRPQDETLTTSARRPAQPALPDPLDAGIAHAVESLLAQQQSDGHWVYELEADA
TIPAEYILMVHYLGETPDLVLEGKIANYLRRIQNADGGWPLFHAGASDVSASVKGYFALK
MAGDNPEAEHMRRARAAIHAMGGAEASNVFTRTLLALYGVMPWQAVPMMPVEIMLLPEWF
PFHLSKVSYWARTVIVPLLVLNSLRPQARNPRKIGIDELFVRPCQATRLPRRAPHQSPLW
VGVFRTLDAVVRMAEPLFPRGLRQRAIERAREFTVERLNGEDGLGAIFPAMVNSVLMFDV
LGVPENDPNRAIARRSIDKLLVVKDDEAYCQPCLSPVWDTSLAAHALLEVGEPRTIAAAA
RGLDWLVPLQELELRGDWTVRRPNVRPGGWAFQYANPHYPDVDDTAVVAAAMDRVDKGDR
SNRYDEAASRACEWIVGMQSSNGGWGAFEPENTHLYLNNIPFADHGALLDPPTADVSARC
LAMLCQLGQMPANSEPAARALRYLLDEQEADGSWFGRWGTNYIYGTWSALCGLNAAGIGT
DAPEMKRAAQWLLSIQNEDGGWGESGDSYKLEYRGYEKAPSTASQTAWAMLGLMAAGAGD
HPALVRGVEYLLRTQASHGFWDEPYFTAVGFPRVFYLRYHGYSRFFPLWALARFRNLLRD
GNRAITWGL
>A0A7Y2HVJ9|squalene-hopene cyclase|EC 5.4.99.17|Phycisphaerales bacterium|TrEMBL
MTTTSTRVDRERLTASLSAAQTALLAQQRDDGHFCGELEGDSILESEYLLMKFILRQEHA
ARPDGSPGRATLEKIAEQLRRQQRPDGGWGQYPGSGVDLSATVKAYFALKLMGDDPTLEA
MQAARAVIRANGGAEHCNSFTNFYLAALGQVPWSAVPAIPPEIVFLPRWSYFHLDTVSAW
TRTMIMPLSIVATLQPTRRLETTDGIDELFIDEEERRRLTASRTPDRWSRFFLGIDRLLK
IAGSGMPLRRIALRRVERWILARAGQDGPAATDGLGAIFPPMVSIQIALDALGYEPEHPA
RVRAEAELDALFIDDGTAIRIQPCFSPVWDTGIALYALTDCGMTEADEPACAAAAWLRAK
ECRHVGDWHRNVRGEVEPSGWYFEYHNAWYPDVDDTAMVAMSLRRTGGAANRRASARGVA
WMLAMQNDDGGWAAFDRTRDRAILERIPFADHNAMQDPSCPDITGRVLECLAWHGLRRDH
PAIDRAVAYIRSHQEPDGAFFGRWGVNYLYGTWQAVVGPVRCGIDPAEPWLERAGAWVRS
VQQPDGGFGETANSYVDPAFRGQGPATASQTAWAAMTLLALAGPHDDAVERAMSWLMTHQ
LDERRAADPEENPDGDPAGSWAETQFTGTGFPEVFYLRYHLYRLYFPLMALGRYRAALQA
AGEERPALKVRPKVVVG
>A0A3S0GKQ8|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobiaceae bacterium|TrEMBL
MTVTSSASARATRDPGNYQTALQSTVRAAADWLIANQKPDGHWVGRAESNACMEAQWCLA
LWFMGLEDHPLRKRLGQSLLDSQRPDGAWQVYFGAPNGDINATVEAYAALRSLGFRDDEP
AVRRAREWIEAKGGLRNIRVFTRYWLALIGEWPWEKTPNIPPEVIWLPLWFPFSIYNFAQ
WARATLMPIAVLSARRPSRPLPPENRLDALFPHGRKAFDYELPVKAGAGGWDRFFRGADK
VLHKLQNLGNRLNLGLFRPAATSRVLEWMIRHQDFDGAWGGIQPPWIYGLMALYAEGYPL
NHPVLAKGLDALNDPGWRVDVGDATYIQATNSPVWDTILTLLAFDDAGVLGDYPEAVDKA
VDWVLQRQVRVPGDWSMKLPHVKPGGWAFEYANNYYPDTDDTAVALIALAPLRHDPKWKA
KGIDEAIQLGVDWLIGMQSQGGGWGAFDKDNNQKILTKIPFCDYGEALDPPSVDVTAHII
EAFGKLGISRNHPSMVQALDYIRREQEPSGPWFGRWGVNYVYGTGAVLPALAAIGEDMTQ
PYIGRACDWLVAHQQADGGWGESCASYMDVSAVGRGTTTASQTAWALMALLAANRPQDKD
AIERGCMWLVERQSAGTWDEPEFTGTGFPGYGVGQTIKLNDPALSQRLMQGPELSRAFML
RYGMYRHYFPLMALGRALRPQSHS
>A0A7W8B3P0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces spectabilis|TrEMBL
MTEQTHTTPPRSATFARSALRQAAADSAKRATAHLQELQHDDGRWQGDMGSNVTTEAEEL
MLHAFLGTLWHDAAQRQRAEQSAAWIRYQQEPDGGWAQYPGGPTEVSTSIEAYASLRLVG
DQASSDHMTAAATRIRAAGGIATSRVYTRFWLALFGCYPWERLPELPPELMFLPGRFPLS
IYRFASWTRATLVPLAVVSAYRPTRYLGLDLSELDPSGDEKNLLLRFPRAPRGRLLSVAG
VALRLDAALRLYRKSPLGVVRKAGLRRAASWIVERQEADGSWCGYHPPVAYSIIALYVLG
YPLEHPVLQAGLKSLDGFSRLTEQGQRRLDVAPSPVWDTALAITALRDAGTAPDDPKLLH
AADYLLGKESRRRGDWAVTRPHVPAGGWAFEADNQLTPDLDDTAEVAMALQSVDHPAPER
VERALQRAQTWALGLQSRSGGWAAFDADNTSRLIGALPFCDFGEVTDPPSADVTAHVIEW
LAGRGLAGTAQLRTACSWILHQQQPDGSWFGRWGANHIYGTGSALPALLAAGLLPSHPAL
CRALDWLVRHQNRDGGWGEDLRSYNDYRFIGRGESTPSQTAWALIGLIAAHHEPAVIDRG
IAWLIDRQQPDGSWVEPQYTAVAFPHDYYMRYDLYRIVFPLTALGRYLSSETGEEY
>A0A5N8XB43|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces spongiae|TrEMBL
MTATTDGSTGAPPPRAASASETDSETDIDPPEAAGVPDAAERAMGRATDFLLSRQDAQGW
WKGDLETNVTMDAEDLLLRQFLGIRDEKTTHAAALFIRGEQREDGTWTTFFGGPGELSTT
IEAYVALRLAGDAPDAPHMAKASQWIRDQGGIAASRVFTRIWLALFGWWKWEDLPELPPE
LIYFPKWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPGRPNPIKPLAP
AASWDGVFQRLDKVLHGYHKVALKRLRKAAMNSAARWIIERQENDGCWGGIQPPAVYSVI
ALHLLGYDLQHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPAD
HPQLVKAVDWMLGEEIVRPGDWAVRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVK
HPDPEGVDKAIARGVRWNLGMQSKNGAWGAFDVDNTSPFPNKLPFCDFGEVIDPPSADVT
AHVVEMLAVEGLAHDERTRRGIEWLLAEQEPNGSWFGRWGVNYVYGTGSVVPALVAAGLP
ASHPAIRRAVAWLETVQNDDGGWGEDLRSYRDSAGWSGKGASTASQTAWALLALLAAGER
EAKTVERGIEWLAGTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEP
FSEKTDHSDGSDRSDGSDRSDGTGKADTTSAPAQGS
>D5C0D5|squalene-hopene cyclase|EC 5.4.99.17|Nitrosococcus halophilus (strain Nc4)|TrEMBL
MTRALRQAPESAGAVDIAAASPATEALPQGIHRTELSAAITAARDALLKLQHADGHWCFV
LEADGTIPAEYILWTHFTGELEPEIERKLAARLRAKQADHGGWPLYEGGDLDISCSVKVY
YALKLAGDDPSAPHMVRAREAILARGGAAQSNVFTRLALAMFAQIPWRGVPFIPVEIMLL
PSWFPFHLNKVSYWSRTVMVPLSILYSLKGQAQNPRDVHIQELFVTPPEQERHYFPIRSR
LNKVLLYVERTARLLEPLIPSALRRHAMKKAETWFTARLNGEDGLGGIFPAMVNAHEALI
LMGYGPDHPLRVQAKKAIQNLLVDEGDSAYCQPCLSPVWDTGLASLALQETEGGHTTAPV
IRALDWLKERQILEQPGDWQKQHPHLKGGGWAFQYNNSYYPDLDDTAVVAWAMDQAAAPE
HYGESIQRACDWLCGMQSRNGGFAAFDSDNTYYYLNEIPFADHGALLDPPTADVSARCVA
LLGRLNQPQYAQSLKRTLDYLRQEQESNGSWFGRWGTNYIYGTWSVLTALEQAGFDPQES
FIRKAVDWLKQVQRSDGGWGEDNYSYFDSSLAGRYQESTPVHTAWALLALMAAGEADSES
VKQGIIYLLQTQQGDGLWDHPAFNAPGFPRVFYLKYHGYDKFFPLWALARYRNHLNRQC
>A0A521QHC2|squalene-hopene cyclase|EC 5.4.99.17|Reyranella sp|TrEMBL
MAMDKLATATRPLDEIEVDIQRAAKALLREQREDGHWVFELEADATIPAEYVLLRQYLGE
PDAPELERKIGVYLRRIQCAHGGWSLFHGGAFDISASVKAYFCLKMIGDSSDAPHMAKAR
EAILAHGGARQANVFTRILLAQFGELSWNDVPTMPVEIVLLPRWFPIHLSRMSYWARTVI
VPLLVLAARRVRARNSRKVAIRELFTTGKAADSRAAHQHRGWATFFKGLDKVLKVAEPLW
PKSLRRRATDRCVRFVSERLNGEDGLGAIYPAMANAVMMFDALGYPPEHPDRATARQAIE
KLLVIRKDEAYCQPCVSPVWDTALVSHAMMEVQGEEASAAALRGMKWLEPLQELEVKGDW
AERRPDVRPGGWAFQYRNAHYPDLDDTAVVVMAMDRARRQFAAGDGYDEAITRGTEWIAG
LQSDNGGWAAFDADNVDHYLNNIPFADHGALLDPPTADVSARCISMLGQLGETPANPMMR
AGIDYLERDQMADGSWFGRWGVNYIYGTWSALCALNAAGFDAARPSVRKAMDWLIAIQND
DGGWGEDCTSYKLDYRGYEPAASTASQTAWALLGLMAAGAVDHPAVSRGIAYLQRTQDDT
GLWQQDAYTGGGFPRVFYLRYHGYPKFFPLWALARYRNLRRANSRRVADGM
>A0A522RCR3|squalene-hopene cyclase|EC 5.4.99.17|Rhodanobacteraceae bacterium|TrEMBL
MPPDSGTPQLDSTIRSNPTARDRLTAAIDAARTRILARQHPDGYWQYELEADCTIPAEYV
LMLHYLGESDRLLEARLAGHLRSHQSRDGGWPLYPGGALDVSCSVKCYYALKLAGDRADA
PHMARARAAILARGGAARSNVFTRIALALFGELPWRGVPFLPVEIVLLPRWFPFTLSKVS
YWSRTVMVPLSVLTTLKPRAANPRGVHIRELFVTQPEQEKHYFHPRSLLNRLLFLGEEIV
RHLERLIPKRVRRRALKRAEAWIVERRNGDGGLGAIFPAMVNAYEALALLGYSAEHPARR
ETRKAIDDLLVVRDDEAWCQPCVSPVWDTGLACLALQEDRDAPENTAQRALAWLTSRQLR
DEPGDWRDYRPNLAGGGWAFQFRNDAYPDLDDTAVVARALHQSPRRAEFADAIARAADWL
VGMQSRNGGFAAFDADNDHQWLNQIPFADHGALLDPPTSDVSGRVLMLLSMLDRAQDRTA
RERVTHFLLAEQTPEGAWFGRWGTNYIYGTWSVLAALRTTGVPADAPAVRRAVAWLKSVQ
QADGGWGEGNDSYLDPELLGRGARSGPAQTAWALLALMDAGDADSPAVARGIEYLLKTQV
DGEWHAARFNAPGFPRVFYLKYHGYNRYFPYWALVRYRNVQWHR
>A0A7V5YI72|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Acetothermia bacterium|TrEMBL
VLKKGLAGFYGEKGFAIEDDETFRLQSCLSPVWDTGLAMIALEDAGLPSDHPALVKAGEW
LLDEQIFVGGDWQVRCNGRPGGWAFEFANDIYPDTDDASVVMMALQRAKLDEKRKSHALD
RGLEWLLAMQSSNGGWGAFDRNNTKALLREIPFADFGEMIDPPSVDVTAHIVELLGQLGY
RVGFRPLDRALAYLKEEQEPDGAWYGRWGVNLTYGIGYVLPALAGIGEDMSSPYVRHAID
WLVNHQNEDGGWGELIEGYKDQNRRGRGPSTPSQTAWALLGLIAAGEIEHPATVGGIEYL
LQTQREDGGWNQPYFTGTGFPVDFMINYHLYRDVFPVMALGRYRRVLWKAFAPEDRMNPM
NSTNSMNPPEESSCR
>E3I0A3|squalene-hopene cyclase|EC 5.4.99.17|Rhodomicrobium vannielii (strain ATCC 17100 / ATH 3.1.1 / DSM 162 / LMG 4299)|TrEMBL
MMDMTGRNGADFAEGSAERFDFDHAHFDRSHGSLADRAFLQERINAASSALLSHQREDGH
WCFEFEADATIPAEYALLVHYLGEEPNLEREAKIATYLRRIQGEHGGWPLFHKGEFDMSA
SVKAYFALKMIGDDIDAPHMVRAREAILSRGGAEMANVFTRILLALFGVVTWRAVPVMPV
EIMHLPRWFPFHMSKVSYWARTVMVPLFVLGALKPVAKNPRRVSVDELFHTNPKKVGPRP
RAEGQSRAWYTFFAGVDACLRVVDPMLPKRSRKSAIGKAVTFVKERLNGEDGLGAIFPAM
ANSVMMYEALGVPENDPDRAIARYSIEKLLFETENEVYCQPCVSPVWDTGLAAHALLETG
GEAEREAAQRGLEWLKPLQVLDVKGDWADQKPDVRPGGWAFQYANPHYPDVDDTAVVALA
LDRAAHLPGSHADSEQSVARAKEWVSGLQSKNGGWGAFDADNTCYYLNNIPFSDHGALLD
PPTVDVSARCVSMLAQLGEKPDTNATMKRGIDYILSEQEKDGSWFGRWGSNYIYGTWSAL
CALNAAGVAHESAAMRRAVAWLVSIQNEDGGWGEDGSSYKLDYKGYEKSPSTASQTSWAL
LGLMAAGEVDNPAVKRGIAWLVANQNEAGTWKEERHNAPGFPRVFYLIYHGYSKYFPLWA
LARYRNLTSGNRAPVMHGM
>A0A538K7N5|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MAGDDGGRGAVGPISGAVAVVGCDNDGGCVTVVQELTALDTAVERGAERLLSLQHPDGWW
KGELESNATMIAEHLFLFHFLGLRDAETDRLLANELLARRRADGTWSIWFEGPPDLSVTV
EAYTALKLAGVDPGEQTREYIRQAGGVARTRIFTRAFLALIGQWPWRRLAHVPVELILLP
PAGPLSVYDFACWARQTMVSLSVVEALRPVRPSSIDLGEIGARKTEPDGRPHLTRVRRHA
LAVAERWVRERQEADGSWGGIQPPWVWSLIMLAALGYGPEDEIFARGLAGWERFMVRDGD
RLRPEACQSPIWDTALAVLALRVAGFSADDSRLQAAGAWLLREEVTVRGDWSIRRPDVAP
GGWSFEFDNDLYPDVDDTAVVVLALRELGIGDAAVRRGLDWLVGMQSRSGGWGAFDVDNE
ALWLYKLPICDFGKVTDEPTADVTGHALEALGHEEGVGSSLGSGLDWLLAEQEHDGSWFG
RWGVNHVYGTGAAVPALEACGLPPGHPAIRRALRWLDSVQQPTGAFGEDIRSYSDPARRG
QGPATPSQTAWALMAYVSGGAATGLSTRRAAEYLCEFQRPDGDWDEQHYTGTGFPLDFMI
RYHLYRLTFPVLALGRLRERLNR
>A0A7U6Y8U1|squalene-hopene cyclase|EC 5.4.99.17|Rhodospirillaceae bacterium LM-1|TrEMBL
MTVTALRTSPESLESAVDRQDNGLSLDAVERTVQTVAEGILKRQKPDGHWVYELEADATI
PAEYIFLNRYLDTPQPELEAKLARYLRSIQNEDGGWPLFHKGASNISASVKGYYALKMVG
DDIDAPHMKLARERIHALGGAEKANVFTRFALALFGQVPWRAVPVTRAEAILLPEWFPFH
ISKVSYWSRTVMVPMFVLCTIKPKARNKGGIGVRELFLADPERIRDWQNNPTGSRLGNFF
LVLDKFLRAIEFFFPKFLEKKSIDKCMEFTLERLNGEDGLGAIFPAMANSVMAMDALGYS
RDDPNFKIARKSIDLLVVEHGDTAYCQPCVSPVWDTGLAAHALMEAGLPGDHPAIAKAMD
WLKDRQVLDVEGDWIWQRPGLRPGGWAFQYRNDYYPDVDDTAVVALALHRAQPGESREAV
SRAAEWVEGMQCGNGGWAAFDAENEKYHLNHIPFADHGALLDPPTLDVSARCLSLLAQLG
YDANHPKVAAGLEYMRIEQETDGSWFGRWGTNYIYGTWSALCAFNAAGEDMNAPHIRRAV
DWLKNRQREDGGWGEDCASYWDESKTLCHESTPSQTAWALLGLMAAGEVDSPEVAKGITY
LMSTPRDMYGKWHEERYTAVGFPKVFYLRYHGYSAYFPLWALARYKNLKRANSRRTAYGM
>A0A6G2N0A4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4946|TrEMBL
MTATTDGSTGATLPSRAAAASDTTLTTPEAAGAPEAAAQAARRATDFLLSRQDAEGWWKG
DLETNVTMDAEDLLLRQFLGIQDERTTQAAAKFIRGEQREDGTWATFWGGPGELSTTIEA
YVALRLAGDAPDAPHMARAAAWIRERGGIAAARVFTRIWLALFGWWKWEDLPEMPPELIW
FPGWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPANPNPPKPLAPANT
WDGAFQRLDRALRQLRKVVPRRLRKAAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVLREGLASLDRFAVWREDGARMIEACQSPVWDTCLAAIALVDAGLPVDHPQ
LVKAADWLLGEEIVRPGDWAVKRPQLPPGGWAFEFHNDNYPDIDDTAEVSLALRRIRHHD
PERTDRAIGRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAAEGLAHDPRTRRGIAWLLAEQEENGAWFGRWGVNYIYGTGSVVPALTAAGLPASH
PAIRRAVTWLESVQNDDGGWGEDLRSYKHVREWAGRGASTPSQTAWALMALLAAGEKDSK
AVERGIQWLATTQREDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFER
QLLARTPGRGPRRPSPPGHRSPRPRGADVNVQPAPAPLLIACALGIEHLALRSGDRGGAG
GPVTFVRTGMGPRAAQRSLTRHLARPALTDAAVVATGFCAGLAPGMHPGDLVVAEETRDP
HGTVPCVATELLVKELARLLPGRTVHTGPLTGSDHVVRGPERSALRATGAIAVDMESAAT
LLSAVTAGERPVAAVRVVVDTPEHELVRIGTVRGGISAFRVLRSVLPAYFEWHRSLLLPR
R
>E8V785|squalene-hopene cyclase|EC 5.4.99.17|Terriglobus saanensis (strain ATCC BAA-1853 / DSM 23119 / SP1PR4)|TrEMBL
MDTPGGNHISEAQRAARAARAASAPPAAQAPAQPRFGRMDLGLDAIGKGIRSSIDWLLGQ
QDAEGYWCGELEADVMLEADYIYVHTLLGTGDQGKMRRAINEILRHQNEDGGWSLYPGGP
SNINYGVKSYFALKLMGHSTEEPYMEKARNWILAHGGVVECNTFTKIYLCSLGQYDYDAV
PAIPPEIVLFPNWFYFNIYEISSWSRGILVPLSIIYAKKPFKKLPPEQSIDELFVGGREN
ANLHLRWDKRFFGWRNFFLFWDRLMHWAERVHIRPLRAKAIKAAEKWMLARFEKTDGLGA
IYPAMLNAIVALRCLGYSVDDPQFIRAMDEFEKLGIDCPEGTPDYPTPTFRMQPCFSPVW
DTAQVLSTLGEAGISRTDPLMIKAADWLLSKEVRHKGDWAEKVRNVEPGGWYFEFNNEFY
PDVDDTGEVLLALKAVDNPRERYQHDATERAINWIFAMQCKNGGWAAFDKDNTKSIFQYI
PFADHNAMLDPPTVDITGRILEMLAAYGYTRRDKRVESAIQFILREQETDGSWFGRWGVN
YLYGTFLVLRGLEAMGMWHQETPILQATEWVRMVQNPDGGWGETCGTYDDAIQKGIGPST
PSQTAWAVLALLAGGDTRSDSVAKGIRWLIERQHEDGSWDELVPGRNGESYYTGTGFPRV
FYLGYHLYKQYFPLLALTTYKKAMEKEAAEKVA
>A0A8F9VQ80|squalene-hopene cyclase|EC 5.4.99.17|Amycolatopsis sp. DSM 110486|TrEMBL
MTQTVPGTSTSDTPRERSRTPEETLAAGIEFLRGEQDAAGWWKGELSTNVTMDAEDLLLR
QFLGILTEQQKEESARWIRSQQRDDGTWANFPGGPADLSTTVEAWVALRLAGDPAHAPWL
VEAAGWIRAHGGLESTRVFTRIWLAMFGQWSWADLPNLPPELIFLPSWFPLNVYDFACWA
RQTIVPLTIVGTLRPKRKLPFDVAELRVGESPKKSAAPWTWDGVFQNLDTALHTYAKLPF
NPVRKVAMRQAAEWILARQESDGSWGGIQPPWVYSILALHLLGYSLDHPALKAGLEGLED
FTVREETEQGWVRRLEACQSPVWDTALAMTALLDAGVSPGDETLVRATEWMLGEEITVPG
DWMVRRPSLAPGGFAFEFANDGYPDTDDTAEVVLALRRMGRPDHLRIRGAIDRSVKWLEG
MQSSDGGWGAFDADNTQVLATKLPFCDFGAVIDPPSADVTAHVVEMLAAEGKADTTECRR
GVKWLLDNQEADGSWFGRWGANYVYGTGAVVPALVLAGMPASDVRIRRAVRYLTEHQNPN
GGWGEDLRSYDDPGKWSGRGESTPSQTAWALLALLAAGERDSAATTEGVAWLCEQQRADG
GWDEDFHTGTGFPGDFYLSYHLYRVVFPLSALGRYVRSSS
>A0A7Y4RVR3|squalene-hopene cyclase|EC 5.4.99.17|Methylococcaceae bacterium|TrEMBL
MLNQTSPISNVSYLFIGTTRSSSKLNCAIDRAKEHLLSLQSNEGYWVFELEADCTIPAEY
ILMMHYMDEINESLQTKIANYIRTQQNSDGSYSLYQGGSGDISCTIKAYYAMKIAGDPIQ
SVPMTSARDWILSQGGAARANVLTRIMLAMFEQIPWRGVPFIPVEVMLLPKWFPFHLEKI
SYWARTVLVPLTILCTFKAKARNPKKIGIAELFVTAPDKEKNYFSHVTTPLGKGFLVLER
MGRFMEPLIPGFVRKRATRKALNWFIERLNGLDGLGAIFTAMVNAYEAMDYLGIPVDNEQ
RQIARASIDRLLVIKDDMAYCQPCVSPIWDTGLASLTLQEIDRHQKDPHTQKALKSALHW
LATKQLKDEPGDWRNQRPNLPGGGWAFQFGNSYYPDVDDTAVVAYAMIQADNKNFADNIE
RAGAWIAGMQSSNGGYGAFDADNTHFYLNHIPFADHGALLDPPTADVSARCIMLLGKLLK
QHPEYQTVIDRCIEYLRNQQEMDGCWFGRWGTNYIYGTWSVLVGFESAGVPKNDPGIRKA
VAWLKSRQRVDGGWGEGNYSYNNTKCRGQFYTSTVFHTSLAVLALLASGEARCPEVKAGV
NYLLNNQQADGFWKDPSFNAPGFPKVFYLKYHGYDKFFPLWALGRYRNENRLSLPNH
>A0A4V6RIM5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. RKND-216|TrEMBL
MTTTAGSGSAAVPAATLGQVHGTPLRRTAEDAAARAVEHLLARQDTAGWWKGDLETNVTM
DAEDLLLREFLGVQDAKLTEASARWIRSRQREDGAWSTFHGGPGDVSTTVEAYVALRLAG
DDPADAHMARASAWVRGRGGVATARVFTRIWLALFGWWRWEDLPELPPELVYLPRWFPLN
IYDFGCWARQTIVPLTVVSAHRPVRPAPFALDELHRDPARPCPPRGRTASAFTWDGVFQR
LDRALHAYRGVALRPLRRSALRDAGRWIVERQENDGCWGGIQPPAVYSVIALRLLGYDLD
HPVLRAGLESLDRFAVWRETPDGPVRMVEACQSPVWDTCLATLALSDAGLPADHPALLKA
GDWMLGEEITRPGDWSVRRPGLPPGGWAFEFHNVTYPDLDDTAEVALALRRLRHPDPSRI
DAAVARAVRWSLGMQSRNGAWGAFDADNTSSLPNRLPFCDFGEVIDPPSADVTAHVVEML
AHEGRADEPATRRAVRWLLAEQEASGAWFGRWGVNHIYGTGAVVPALVAAGVPDGHPAIR
RSVAWLEKVQNDDGGWGEDLRSYPEPDWVGRGASTASQTGWALLALLAAGERDGQAARRG
VEWLARTQREDGSWEEPWFTGTGFPWDFSINYHLYRQVFPLMALGRYLHGNPEPRAAA
>A0A6L6WZY4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces typhae|TrEMBL
MTATTDGSTGAVTPRAASATGTTDTTPAAIGAPDAAARAIRRSTEFLLSRQDAQGWWKGD
LATNVTMDAEDLLLRQFLGVQDETTNRAAGLFIRGEQRADGTWASFHGGPGELSVTIEAY
VALRLAGDAPDEPHMARASAWIREQGGVASARVFTRIWLALFGWWKWDDLPELPPELLYF
PKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHADPRFPNPTKPLAPVASW
DGVFQRLDKALHLYHKIAPRGVRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVLKAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHPQL
VKAADWMLGEQIVRPGDWSVRRPGLTPGGWAFEFHNDNYPDIDDTAEVVLALRRVEHPDR
ARMEHAIARGVRWNLGMQSKNGAWAAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMAAYEGLADDPRTRRGVEWLLAEQEAFGGWFGRWGVNYVYGTGSVLPALTAVGMPGSHP
AIRRAVAWLESVQNDDGGWGEDLRSYREERWIGHGASTASQTAWALIGLLAAGERDSTAV
ERGVRWLARTQRDDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPFAGVS
GKGS
>A0A0S4LL26|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Nitrospira nitrificans|TrEMBL
MNIIKALFNRLSDSLLSTVHGRLDPAAELTPVASLRLVSDKPVILPSLDSSATRRPIGHA
VSQPDAVDDAIRRSQSWFFNRQHAEGYWVAELEADTTLTSEYIMLRRFLDRIDPDREAKA
VRYLQTTQLPDGGWPIYYGGPAEISASVKAYFALKLSGVSADEPFMVRAKERILAMGGVL
QANVFTKITLALFDQYDWEGVPHMPVELMLLPKKFYFSIYAISYWSRAVLIPLLIVFAHR
PVCRIPREQGIDELYSTPRPEVRYWKYPPFNKDQAWFTPHNFFVALDVMLKLYDRMPMRV
LREKALHKAACWMVDHLKGSGGLGAIYPAMANSIMALKCLGYDADDPLVVKALREIEALE
VCDSAMIDSEVVPTLHLQPCFSPIWDTALLTNALVEAGVPQDHPALQKAGRYLMSRQTKT
VGDWIISSPNAEPGGWYFQFENESYPDVDDSAVVIMALSKLKISGQENELNESIRRGMQW
VLAMQGSDGGWGAYDKDNNRVVFNYIPFADHKALLDPSTSDLAGRCLEMLGALGYDKTHP
AAGPALAFLKKEQEKDGSWYGRWGVNYIYGTWSVLAGLRAIGEDLSAPYIRRAVAWLESR
QNPDGGWGESCLSYRDECEFHGKGDSTPSQTAWALMALMSAGAIDSFSVARGVQFLLRWQ
MKDGSWEEISHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRSRGKIRAEELRHHIQGP
DTYRSEH
>A0A554U4J7|squalene-hopene cyclase|EC 5.4.99.17|Mycobacterium sp. KBS0706|TrEMBL
MTISSPSFQSEDLAGPTRASLDDAIGRGVGGLLGLQREDGHWAFILEADATIPAEYILLK
HFLGVVDREKEALLATYIRSIQSKVHDGWPLWHDGPLNISASVKAYFALKAAGDDPDAPH
MARARAAILAAGGAARSNVFTRILLALFEQVPWRAVPVMPVQIMVLPSWFPFQLNKVSYW
SRTVIVPLLVIMAKKPRPVNPGALSIQELMVEPPEQVKNWHVHVDGTFWGRFFRRLDGVL
RPIELFFPRRQKSIEKAVAFVTERLNGEDGLGAIYPAMANSVMMFKCLGYADDHPDLKIA
WASVEKLVDTVDGVTYAQPCLSPVWDTALTAHALLESDDPEAVARAKRGLDWLVPRQVLD
VKGDWAERRPDVRPGGWAFQYNNAHYPDLDDTAVVVMAMHRADPERYREAIDRGVEWLLG
LQSKNGGWAAFEVDNTYHYLNHIPFADHGALLDPPTSDVTARCLSMLGQLGRRIDDPAVA
RGVEFLRQEQERDGSWFGRWGTNYIYGTWSVLCALNAIAMDPQDPMIRRAVDWLAAQQRE
DGGWGESGDSYYEGKPEMTPATSTASQTAWAVLGLMAVGEAGHPAVERGVAWLSAHQRAD
GLWDEPSFTAVGFPRVFYLRYHGYPAFFPTWALSRYRRLRDSNSGRVEVGM
>A0A4Q0MAZ7|squalene-hopene cyclase|EC 5.4.99.17|Hansschlegelia zhihuaiae|TrEMBL
MDFVLETSDIISEADRCANRAAEAMRAAQREDGHWVFELEADATIPAEFVLLKHFLGEPR
DAALEAKIGVYLRRIQGDHGGWPLFHGGALDVSASVKAYFALKVIGDDVDAPHMARARAA
ILAAGGAEAVNVFTRIQLALFAAGPWDAVPMLPVELILLPRWFPVHLSKMSYWSRAVIVP
LLVLGALKPVARDRSVRVDELFTGRRTSPTSKAAGAKPLWGALFNGLDAVLKRVEPFFPK
TLRQRAIDACVAFVVERLNGVDGLGAVYPAMANCVMMFACLDYPEDHPHRAAARESLERL
LVIGEDEAYCQPCVSPVWDTALAAHAMMEAGDDASARAALDWLKPLQVLDLKGDWAERRP
GVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRAKGRSGGAYDEAIARGAEWTAGLQSRDGG
WGAFDADNSHHYLNNIPFADHGALLDPPTSDVTARCLSMLAQLGERDTPRVKAALAFLEK
EQMPDGSWFGRWGVNYIYGTWSALCALNAAGVDPASPMVRRAVDWLVSIQNDDGGWGEDC
ESYALDYAGYAPAPSTASQTGWALLGLMAAGAVREPAVERGVRHLVATQGADGFWRQDFH
TGGGFPRVFYLRYHGYPKYFPLWALARYRNLVRSNGSSVAFGM
>A0A661FQV8|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MFTEDYNNMSNIHSLDNAVKKAQDKLLSLQHKDGYWLFELEADCTIPAEYIMMMHYLDDI
DQELQAKIAVYLRNRQSEDGSYPLFQGGVGDISCSVKVYYALKMAGDQPDQPHMVLLRNY
ILSQGGAAKANVFTRIALAIFEQLPWRGVPFIPVEIMLLPKWFPFHIDKVSYWSRTVMIP
LFILCTLQAKAKNPLNIDILELFVVHPDKEMHYFPERGLLNQFFLFLDALGRKSRILVTR
KMHQTAVARAKNWFTERLNGEDGLGGIFPAMVNAYQAMLLLGMPADHEHVITARKAIDKL
LVIKDDEAYCQPCLSPVWDTGLTLLALQEADLPATQASRKRAYDWLKTKQLSDEPGDWRI
QRPNLDGGGWAFQFENPHYPDVDDTAVIAYGMATANLPDMDESIHRATRWIVGMQDNNGG
YGAFDVDNTYYYLNEIPFADHGALLDPPTADVSARCVMLMAKVAQDHDEYLPAYNRCLDY
IRNDQEDDGSWFGRWGTNYIYGTWSVLIALEHTDIAKTDPLYTKAVTWLKSIQHEDGGWG
EDNQSYHDESFRGQFHTSTAFQTAWATLALMAAGEHDSKEVRAGIDYLLAHQNQDGLWTD
NCHTAPGFPRVFYLKYHGYDKFFPLWALARYRNEKNNK
>A0A523MCG5|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MAVNATDTVQTKSQLDDAIARATHWLDEEQDPEGFWVGMLESNSCMEAEWLLLMHFLDYT
HPRKQDLVNSILNAQRSDGAWESYYEAPSGDINSTVECYAALKAVGMSADDEPLVKAREW
IFAHGGLSSIRVFTRYWLALLGEWPWDKTPNLPPEVIANPRWFPFNIYNFASWARATLLP
LAVLSARRAVRPLPIESRLDELFPDGRERMNYKLPRRGRAFGWRRLFLFSNHIIHWYQRI
GLTPGRETAIKACVEWIVRHQDSDGAWGGIQPPWVYSLMALNVENYSLSHPVMAKGLGAL
DSHWSYERDGTLHIQASESPVWDTLLALLAMQNCDRPFNTGMDNALEWLLDKQVTDFVGD
WGQKIKRVEPGGWPFERANLHYPDVDDAAVALIVLAQLPEPQRSSARVQTAIERGRQWIL
ALQCRKGGWAAFDKDNDKLIITKIPFCDFGEALDPPSADVTGHVLEAFGLLGMSREDRAV
KRAYQYLLTEQETDGSWFGRWGVNHIYGTAAVLPGLAAIGDDMASPHVRRAVHWIIEHQN
TNGGWGETCASYMDEKLRGRGPSTASQTAWAIMALVAADHRSSDAAILRGLDYLLITQRR
DGTWDEPYYTGTGFPGYGFGGRLDFRDKDTKQRIAQGTELQRGFMINYNLYRHYFPLMAM
GRARARPAGASAR
>A0A534BZV2|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MNRGSPTRDSLAVAPNAARSEAPAHKVHRLTEFSPLDRAIAAARDALISVQSSQGYWLFE
LEADCTIPAEYVLMMHFLEEIDAPLEAKLAAYLRARQAEHGGWPLYHGGDFDMSCSVKAY
FALKLAGDSPLAPHMVRARAAILERGGAARSNVFTRITLALFGQIPWRGVPYIPVEIVLL
PRWFPFHLNKVSYWSRTVMVPLLILCTRKPVAANPRNVQIRELFTTPPEQERHYFRGPGG
RADILSRVFLALDRLGRMIDPLVPNAMRAYATRRAEAWVLERLNGEDGLGAIFPAMVNAL
EALAVLGYASSDPRRLAAKRALDKLLVVDPSSAYCQPCVSPVWDSALASLALQETGGAGA
LAASVRALDWLQPLQLPDAPGDWRVRRPHLAGGGWAFQFSNSHYPDLDDTAVVAWSMHQA
SDPARYSHTVQCALDWLVGMQSRNGGFASFDVDNTHYYLNKIPFADHGALLDPPTSDVTA
RVVTVLARVGRPQDQAALGRAIAFLRAEQEADGSWFGRWGTNYIYGTWSVLTAFAQAGIS
PDDPATRRAVSWLVARQHADGGWGETNDSYADRHPAGGKSASTPHQSAWALLGLLAAGEA
GSAAVRRGVEYLLRSQQADGLWSDPTFTAPGFPRVFYLRYHGYCAYFPLWALAAYRTLTR
LGTTH
>A0A534CML1|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MSRKAGTSAALAGTEVLLRADAPARRLPGEKLSPLEYAIAAARDELIRLQRPDGSWELEL
EADCTIPAEYIMMMHFLGELDSALEAKLADYLRQRQAGYGGWPLYHGGAFDMSCSVKVYF
ALKLAGDDPESPHMARARAAILERGGAASCNVFTRIALALFGQLPWRGVPYIPVEIMLLP
RWFPFNIHRVSYWSRTVMVPLLILCTLKPRARNPRNVDIRELFTTPPEEERRYFRRPLGG
SAALARAFFSLDRLARSLDGLIPRALREHALKRAEAWMLERLNGEDGLGAIFPAMVNALE
ALAVRGYSPDHPHRRGAKRALEKLLVEDYSSAYCRPCVSTVWDTALAGLAMQEEGSAGAR
AAALRGLEWLEPRQLLDDPGDWRTRRPHLPGGGWAFQRANSYYPDLDDTAAVAWSMHRST
DPGRFSFALSRALDWLVGMQSENGGFASFDVDNTSYYLNEIPFADHGALLDPPTSDVTAR
VVTALARVGRPEDRAALTRAIDYLRREQEANGSWFGRWGTNYVYGTWSVLSAFAAARIGP
DDPAVERAVSWLESRQNPDGGWGESNDSYEPGRAGTSAPSTPHQSAWAVLALIAAREAGS
DAVRRGIEYLLRTQRPDGLWSDPSFTAPGFPRVFYLRYHGYCAYFPLWALAAYRNSTAAG
PGTVH
>A0A523MS86|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MTLIKPETSPVVHAGPVRAWPPGLAAGIEAALGWSEANQDPAGFWCGTLESNACMEAEWL
LAFHLLGYDYAHRDALVRGILQRQRSDGAWETYFDAPSGDINATVESYAALRANGISPDS
DELRRARAWIQGHGGLANIRVFTRIWLAMIGEWPWRAVPNLPPEMIHMPLWTPFNIYHFA
SWARATIVPLAVLSARRHVKPLPPEHRLDELFPDGRENFDYSLPRRGRRLSWSGFFRTAD
RVLHAIQNGGWTPGRRRAVRRCVDWVIRHQDADGAWGGIQPPWIYSLLALHAEGRTLSDP
VIARGLEALDKHWYYERDDARMIHASESSVWDTALTALAMLDNGLQVETSPALRRAIDWL
LANEVRVRGDWSVKAPHVEPGGWAFERANLNYPDIDDTAVVLIVLARVRRQLAADSVWRG
ELAAAIDRGRHWMLAMQSSNGGWASFDRDNDSAVLAQIPFSDFGEALDPPSADVTAHVLE
ALGELGFDRTAPAVARGLAFLRREQEASGSWFGRWGVNHIYGTAAVLPALRAVGEDMRAA
DIRRAAAWLAARQNRDGGWGETCASYMDPAWIGRGVSTASQTGWALMGLIAVDDEAHAQV
IDRGTNFLLSTQRDGTWHEREYTGTGFPGYGVGARTALDNPGLGRRLGQGAELQRAFMIN
YNLYRHYFPLMALGRVNARR
>A0A5S4H3D3|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura geliboluensis|TrEMBL
MTTTEAPGLTGAAAAAVDAARGHLLGLQSPEGWWKAELETNVTMDAEDLLLRQFLGIRSE
AETKDAARWIRAQQREDGTWANFHGGPADLSTTIEAYVALRLAGDPVDADHMRRAAKFAR
DAGGIEGSRVFTRIWLALFGQWSWDDLPVMPPELMFLPSRVPLNVYDWACWARQTIVPLT
ILGSLRPVRDLPVDLAELRAGTVPPKDAKGWGRAFNALDRVLHVYEKRPVRPLRTAAMRR
AADWIIARQEADGCWGGIQPPWVYSLMALNVLGYDLDHPVIKRGLDGLERFTIRDEKGRR
LEACQSPVWDTVLAMNALGDAGAAPDDPALVRAAHWVLGEEVRGPGDWSVRRPGLPPGGW
AFEFDNDVYPDTDDTAEAILALRRTSLPEADAPIERAVRWLNGMASRDGGYGAFDADNTR
ELCTKLPFCDFGAVIDPPSADVTAHVVEALAKEGLAETTVVKRAVVWLLKAQEEDGSWFG
RWGANHVYGTGGVVPALIAAGVRPEKPAIRRAVAWLEQHQNEDGGWGEDLRSYDDPSWIG
RGESTPSQTAWALLALLAAGERSAAVDAGVRWLVENQRPDGNWDEDNFTGTGFPGDFYIN
YHLYRLVFPISALGRYLDGSS
>A0A7K2W6A9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID2888|TrEMBL
MTATTDGSTGALPARADSASETDAPFPQAAGTVGTQDAAEHAMRRATDFLLSRQDAQGWW
KGDLETNVTMDAEDLLLRQFLGIRDERTTHAAALFIRGEQRDDGTWATFYGGPGELSTTI
EAYVALRLAGDAPHEPHMAKASAWIREQGGVAASRVFTRVWLALFGWWRWEDLPEMPPEL
IYFPKWMPLNIYDFGCWARQTIVPLTVVSALRPVRPAPFPLDELHTDADDPNPARSLAPL
VSWDGVFQRLDKGLHGYRRVAPRRLRRAAMNAAARWIVERQENDGCWGGIQPPAVYSIIA
LHLLGYDLQHPVMREGIASLDRFAVWRDDGARMIEACQSPVWDTCLATIALADAGVPADH
PQLVKAAEWMIEEQIDRPGDWSVRRPQLPPGGWGFEFHNDNYPDIDDTAEVVLALRRVGH
RDRERAEQAIARGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFSDFGEVIDPPSADVTA
HVVEMLAVEGLAHDPRTRRGIEWLLAEQEADGSWFGRWGVNYVYGTGSVVPALVAAGVPG
AHPAIRRAVGWLEGVQNSDGGWGEDLRSYAYAKEWSGRGASTASQTAWALLALLAAGEKE
SKAVVRGIEFLARTQNEDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPF
TGAEGS
>F8JII4|squalene-hopene cyclase|EC 5.4.99.17|Hyphomicrobium sp. (strain MC1)|TrEMBL
MTFESTSQSTRLASEITARELTPSEIEGAIAAAKNALLALQRDDGHFVFELEADATIPAE
YVLMRHYLAEPVDAVLEGKIANYLRRIQSEDGGWPLVHDGASNISASVKAYFALKMIGVG
IDEPYMKKARGWILSQGGASHSNVFTRNLLALFAVIPWTGVPVMPVEIMVLPRWFPFHLD
KISYWARTVVVPLTVLNALKPQARNPLGVGIAELFTIPPDEVKVWPKGPHQKSPWSEIFG
AIDRVLRFTEPHFPKSLRKKSIDKAVAFVDERLNGEDGLGAIFPAMVNALLVYDALGYSK
DHPNYQTARGSIEKLVTVNDDEAYCQPCLSPVWDTALSAHALMEVGDAETEAASDRALQW
LKPLQVLDTVGDWAATRPNVRPGGWAFQYANPHYPDTDDTAVVAMAMDRTLGRTQQPDTT
YREAISRAREWIVGMQSKNGGWGAFDADNTYEYLNQIPFSDHGALLDPPTADVTARCLSM
LAQLGDRPGNSYELDRGIAYLKRTQEKDGSWYGRWGMNYIYGTWSVLCALNVAGVEPSSS
VVRKAVDWLLAIQNKDGGWGEDSESYTLDYRGYEAAPSTASQTAWALMGLMAAGEIDNPA
VKKGIAYLTSTQASDGFWNEKRFTATGFPRVFYLRYHGYSKFFPMWALARYRNLKASNTK
AVLVGM
>A0A6B1H1Y9|squalene-hopene cyclase|EC 5.4.99.17|Holophagales bacterium|TrEMBL
MIDAAVRNLLGQRRDDGHWCAELEGDTILESEYVLLLHFLGRGDDPRVAACCERLRGQQQ
QDGGWAIYPDGPTDPSVSVKAYLCLKLAGDDPQSPRMADARRAILRAGGLRACNSYTRLY
LSIFGLWTWRRSPAVPPELILLPRWFYFNLHEMSSWTRTIVVPLSVIWALKPSVPLDLTL
DELQGDSRPGRKRATLYESFWSFVFAGVNGLIKLVEVIGPVPGWRRPALKKAEEWLVAHV
EGSDGLGAIFPAMVNAVIAFRCLGYEESHPLVQGQLRELERFEIEEAGEMRLQPCLSPVW
DTALSVGALLAADMDGNDAPIQEAVEWLLEREITVAGDWREKSLQDASGGWCFEYRNDHY
PDCDDTAEVLLVLAAVRDRAGELEARKQAAAARGKRWLLGLQNPDGGWASFDRCCDKEVL
TLIPFADHNAMIDPSTPDITARVISALLAHGHDPGDGPVRRATDYLLREQEKDGSWPGRW
GANGIYGTWLALSALAPLATRTGGRPEERLSRACRLGWRWLLAAQNEDGGWGESLRSYDD
PAFRGRGRSTASQTAWAMMGLIAWLEARPWNGDVALTVAALDRAVAFLQERQRDDGSWYD
RDWTGVGFPGVFYLRYHGYAQYFPLEALAAYRRLAVPEPDAMPANGPF
>A0A7Y5RC74|squalene-hopene cyclase|EC 5.4.99.17|Acidobacteriaceae bacterium|TrEMBL
MREQFGSAVPAIVSVGSLELDQQNEEISQQSITRLEQQLLLTAEALLRKQHADGYWCGDL
TADSTLASDYVLLQLWLFPPEEGGAWTPPHPQRIGKLVRYLKACQLTDGGWNLFAQGEAD
VNATVKAYTALKIMGEDVDSRCMRAARERILELGGLQACNSYTKINLSLFGLFPREFVPT
VPAEIMIVPGSFLYEMSSWTRTIIVPLSIIQGLGAQRTAPSGMTLQELIYPGSPITMPRR
DLTSELFLHADKLLKHWERRGVQKIRGRAIAAAERWMLEHLQHSEGLGAIYPSMMYAIMA
MDSLGYERDQPDMIEAIRHFDELLLEREDSIEFQPCKSPVWDTAIAAFALGETGEVDATA
MTRAADWLLSKEVRRKGDWSAKRPNLRPSGWAFEFANDFYPDIDDTAMVLLALQHIRASN
PERQARAEQRAIDWLLGMQSADGGWAAFDVDNDWQLLNKVPFADHNAMLDPTCADITGRV
LEALSKRGLGPKHPAIVRGVQYLLSSQEQNGSWYGRWGVNYVYGTFLAMRGLIATGDARA
HGAVEKAARWLLSVQNEDGGWGESCVSYEVDRFVAAQSTPTQTAWALVGLMACGKTRSAQ
VQKGVQWLLANQRADGDWDEALTTGTGFPNVFYLSYHLYRMYFPVLALATYRRELTRPAL
SVQF
>H0TEF6|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. STM 3843|TrEMBL
MTLNGKTLAATVSAPDNFQTALHSTVRAAADWLIAHQKGDGHWVGRAESNACMEAQWCLA
LWFMGLEDHPLRPRMGQALLQTQRADGSWQIYFNAPNGDINATVEAYAALRSLGHRDDEP
VLQRARQWIEAKGGLRNVRVFTRYWLALLGEWPWEKVPNIPPEVIWFPVWFPFSIYNFAQ
WARATLMPIAILSARRPSRPLPAENRLDALFPKGRGAFDYELPVKADAGGWDKFFRGADK
VLHALQNLGNWLNLGLWRPAAMSRVLEWMIRHQDFDGAWGGIQPPWIYGLMALYVEGYPI
NHPVVAKGLDALNDPGWRVDIGEATYIQATNSPVWDTILTLLAFDDAGVIGDYPEAVEKA
VNWVLARQVRVPGDWSVKLPHVKPGGWAFEYANNYYPDTDDTAVALIALAPLRHDPKWQA
KGIDEAIQLGVDWLIGMQSQSGGWGAFDKDNNQQILTKIPFCDFGEALDPPSVDVTAHVI
EAFGKLGLSRNHPTMVRALDYVRREQEPSGPWFGRWGVNYVYGTGAVLPALAAIGEDMSQ
PYIQRACEWLVAQQQDNGGWGESCASYMDISAVGRGTATASQTAWALMALLAANRPGDRE
AIERGCLWLIEHQSAGTWAEPEFTGTGFPGYGVGQTIKLTDPSLQQRLMQGPELSRAFML
RYGMYCHYFPLMALGRTLRPQAHGKAQSTPAANAVI
>A0A6G2S6V4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8354|TrEMBL
MTATTDGSAGPRPPRSSSATRTTTVLQDTAEAAREATARATDHLLSLQDPAGWWKGDLET
NVTMDAEDLLLRQFLGIQDPKLTEAAGRHIRGEQRADGTWATFYGGPGELSTTIEAYVAL
RLAGDAPDTPHMATAAAWIRAHGGIAAARVFTRIWLALFGWWKWDDLPELPPELIYFPKW
FPLSIHAFGCWARQTIVPLTIVSAKRPVRPAPFALDELHADPRDPNPPRPLAPVASWDGL
FQRLDKALHLYHKVALRRPRAAAMRSAARWIVERQENDGCWGGIQPPAVYSVIALHLLGY
DLDHPVLRAGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHPQLLRA
ADWMLGEQIDRPGDWSVQRPELPSGGWAFEFHNDNYPDIDDTAEVVLALLRVRHPDPHRV
QAAVDRAVRWNAGMQSKNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTAHVVEML
AETGRAHDPRTRRGLAWLLAEQEPSGAWFGRWGTNYVYGTGSVLPALTAADIPASHPAVR
RAVGWLERVQNDDGGWGEDQRSYQDKEGWAGRGASTASQTAWALMALLAAGERDGEAVRR
GVRWLVETQLPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGGPATGQAAG
APVGD
>A0A7W6YZ68|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia fungorum|TrEMBL
MNDLSQAQPLDAVLPGFAEAAPNVPNLTPESASATASQAVATSLDAAITRATDAILAAQN
PDGHWVYELEADATIPAEYVLLVHYLGETPNLELEQKIARYLRRIQMADGGWPLFTDGAL
DISASVKAYFALKMIGDSPDAEHMVRAREAILANGGAETVNVFTRILLALFGVVSWRAVP
MMPVEIMLLPSWFPFHLSKVSYWARTVIVPLLVLNAKRPVARNPRRVRIDELFRGAPVNT
GMRERAPHQHQGWFRFFSGVDVMLRMVDGLFPKVTRERSVREAVRFVDERLNGEDGLGAI
FPAMANSVMMYDVLGYPADHPNRAIARQSIEKLLVIKDDEAYCQPCLSPVWDTSLVAHAL
LETGEAHAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYNNAHYPDVDDTAV
VAMAMQRSAALTQSDVDREAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGA
LLDPPTADVSGRCLSMLAQLGEFPKTSEPAQRALDYMLKEQEADGSWYGRWGLNYIYGTW
TALCSLNAAGLPHDDPRMKRAAQWLLSIQNEDGGWGEGGESYKLDYRGYERAPSTASQTA
WALMGLMAAGEVNHEAVSRGVAYLQREQREHGLWDETRFTATGFPRVFYLRYHGYRKFFP
LWALARFRHLKRNGLTRVAVGM
>A0A6L7LDJ2|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
MTTRETSESSVSPGLLDAVSKAVSRSQDYFARTQSPGGYWWGELESNSTMEAEYLMLTHF
LGIGDEDTCRKLANHLLETQREDGTWGQYYGSPGDLSTSVECYFALKLAGLSPDDPRMIK
AREFILSKGGVPQARVFTKIWLALFGQWDWKRVPAILREMALLPCWVRMNLYDFSSWARA
TMLPLSIVMTHRPSCRIPDSAAIPELFPNEQKNPPRLRTMVGPAGVFHLADWIFRWYNRL
PWHPMRRLAIRRAVKWIVEHQDKDGSWGGIQPPWVYSLISLKVLGYDLNHPVMRKGIEGF
RAFTIEENGAMRVQACVSPVWDTCLAMVALEDSGLPPDSPILSRAGEWLIRAQVADGGDW
QVRVKNTTPGGWAFEFANSAYPDIDDTAEALIALKSVDTEDPERQRKAIRRGAEWMLGMQ
SKNGGWAAFDKDNTRRAVAAIPFADFGEMIDPPSADVTAHVVEALVRVGYPADMAPLRKA
ALYLWNEQEEDGPWFGRWGVNYIYGTGAVLPALKAMGEDMSAGAVRRAVAWLVAHQNGDG
GWGESCASYADLALAGQGPSSASQTSWALLALLAAGESDSHAVRRGIKYLVATQREDGTW
EETWFTGAGFPGYGVGSRSKRARSQGVELPSGFMIKYHLYRNYWPLMALGRFRRCSERCP
NRGRLIQ
>A0A3L7JXN0|squalene-hopene cyclase|EC 5.4.99.17|Falsibacillus albus|TrEMBL
MTNGIIQDEIERIVQQLKLDQLPNGSWDYPFETGVITDAYMIILLRSLEWNDEELIRSLV
ARIKSLQEGNGAWKLFHDEPEGSLSLTIDAYYGLLFSGYSKINEPHMIKAQKFIIKHGGL
KEAKLYTKLLLAMTGQYKWPSFFPLPPEFMLLPKSFPINFYDISVFGRANLAPLIILASN
KYHHDQSGPSLSHLYITRSGQDDWEEYRSKDWNTFFASIQRGIKSLVGVPARLKTMGIEK
AKNYTLDRIETDGTMLNYFSSTFYMVFALLSLGYPRDHAIIQAAVDGLKSMACTIDGHVH
IQYTTANVWNTALISHALFKAGEPEESQTLMNSVHYLLTQQHNKYGDWMYHNDKAKPGGW
GFSHDNTINPDVDDTTASLKSTIPYIPLDPYCMEVWQNGIQWVISMQNPDGGWPAFEREL
NNPILHLIPMEGAEFILLDPSTPDLTGRTLEFLGNHTHSIKPRKKLQRGIDWLIDNQEKD
GSWYGRWGICYIYGTWAAVIGMIAAGISPLHPSVQKAVQWLKDIQNDDGGWGESCLSDTR
KTYVPLNESTLTHTSWALETLIAASDEPTKEIEEGIHFLIREGRRNNWTTAYPKGQGMAS
FFYIHYHSYRHVFPLMTLLSYKENFGEI
>A0A073CK04|squalene-hopene cyclase|EC 5.4.99.17|Planktothrix agardhii NIVA-CYA 126/8|TrEMBL
MIFSETIAGVKQITMEIQNQVSVTKLKDAIATSQNFLFSQQYPEGYWWAELESNVTIISE
IILLHKIWGTDKTRPLYKAETYLRSQQRDHGGWELFYGDGGELSTTVEAYMALKILGVSE
TDSALIKAKQFILERGGITKTRIFTKLHLALIGCYEWRGIPSIPPWIMLLPEGSPFTIYE
MSSWARSSTVPLLIVFDKKPVFRFNSSLNLDELYVERRENAIFKLPKNNDWTDIFLDLDQ
IFKFAELFNIVPLREQGLKAAEKWILERQEITGDWAGIIPAMLNSLLALKCLNYPVSDPI
VQRGLEAIDNFAIETEESYRMQACVSPVWDTAWVVRALIESGIDPNNADIVKSSKWLIRQ
QILDYGDWNIKNKQGKPGGWAFEFANKFYPDLDDSAVVVMALNQAKITDEPLKTATIIRG
IDWMISMQCKAGGWAAFDIDNDQDWINAVPYGDLKAMIDPNTADVTARVIEMLGELDPNS
SEFQLKIQSLKPSIERAISYLKQEQETDGSWFGRWGVNYIYGTSGVLSALAVINPIYKNW
GYTSLNPLMERGTNWLVSCQNIDGGWGETCHSYNDPKFKGKGVSTASQTAWALIGLMATG
CYEMEVIQRGINYLISIQLSDGRWDESEFTGTGFPGHFYIKYHYYQHYFPLLALGRYQKL
QQL
>A0A660RW58|squalene-hopene cyclase|EC 5.4.99.17|Thermodesulfobacteria bacterium|TrEMBL
MITDSLQQGIEKGVSWLLDNHQPEGFWVGNLETNSCMEAEWVLAMHFLGVKDDPKYESVI
RAILNEQRPDGSWEVYYQAPMGDINTTVECYTALRASGMPVDALPLRKAREWISEHGGLG
GLRVFTRYWLALFGEWPWDATPALPPEIIFLPSWAPFNVYQFASWARGTIIPLTVLRSRR
PVRKLPPEHRIDELFPGTRDRFDYRSAGKKNVSFWQRPFYLFDRLLSRYTGFPFHPGREL
AIRQCLEWIIRHQEADGAWSGIQPPWIYSLMALNVEGYALDHPVLAAGLDAWNQHWKFEK
NGATYLQASDTPVWDTVLSLLALLDCQQDFNATPQMQAALEWILNEQVMAGGDWQVYVKD
VEPGGWAFERQNDFYPDVDDTAVAIIVLLRLLPVLGPGLRSRVDLAVRKAVAWMNAMQSS
NGGWGAFDKDNNSRFITLIPFCDFGETLDPPSADVTAHVLEALGLLGRGMDDPVVARAYR
YIRSEQEEDGSWFGRWGVNHIYGTAAVLPALKAIGEDMNAPYVQRAARWIADHQNPDGGW
GESCGSYMDTALRGCGPSTASQTGWALMALLATGSHAYDQVIERGLAWLLATQRADGTWD
EPQYTGTGFPGYGIGERTDIAKAADDLDQGSELARGFMLNYNMYRHYFPLMAMGRARRHL
SE
>A0A840Z1R5|squalene-hopene cyclase|EC 5.4.99.17|Stakelama sediminis|TrEMBL
MDATLTQSDPNALDHVDRAVNRATAALGKAQRPDGHWVFELEADATIPSEYVLLRHYLGE
ARDTELEAKIATYLRRRQGTHGGWPLFHDGEFDLSATVKAYYALKMIGDDVDAPHMRRAR
EAVLAAGGAAASNVFTRIQLALFDAGPWDAVPTMPPELILLPRWFPIHLSKMSYWARTVV
VPLLVLAAKKPVARNPLRVRVDELYTGEAVTPERRVADEKWLWTIGFNTLDRVLKRVDGL
WPEKTRKRAIDACVAFVEERLNGEDGLGAIYPAMANSVMMFDCLGYAEDHPSRAIARKSV
EKLLVIHADEAYCQPCVSPVWDTALAAHAMLEVGDETAEKRAEAALDWLGPRQVLDVKGD
WAEERPDIRPGGWAFQYNNAHYPDLDDTAVVVMAMDRARAKSDADRDEAIARGAEWTVGL
QSRDGGWGAFDADNAYHYLNNLPFADHGALLDPPTADVSARCVSMLAQLGEPTDSARMQA
ALGWLEKAQEADGSWFGRWGVNYIYGTWSVLCALNAAGVAPDHPMVAKAVAWLKSIQNPD
GGWGEDCDSYALDYEGHRPAPSTASQTGWALLGLMAAGEVDSDSVARGIGWLAEHQQADG
LWGQEFYTGGGFPRVFYLRYHGYPKYFPLWAMARYRNLKRSNTRRVAHGM
>A0A6H2BYE5|squalene-hopene cyclase|EC 5.4.99.17|Dolichospermum flos-aquae CCAP 1403/13F|TrEMBL
MQTQDRIKVKQVVDAIAASQKHLLSIQNPDGYWWAELESNVTITSEAVLLHKIWGTEKTR
PLHKVENYLRSQQREHGGWELFYGDGGDLNTTVEAYMALRLLGVPATDTALLKAKSLILA
KGGISKTRIFTKLHLALIGCYNWRGLPSLPPWVMLLPDNFFFNIYELSSWARSSTVPLLI
VFDRKPIFNIDQPINLDELYAEGVNNVCWELPKNGDWSDIFNILDDGFKLAESINFVPFR
NEGIKAAEKWILERQEVTGDWGGIIPAMLNSLLALKCLDYDANDPVIERGLKAVNNFAIE
TENSYCVQPCVSPVWDTAWAIRALIDSGFAPNDPAIVKAGAWLIEKQILDYGDWNVKNKQ
GKPGAWAFEFENRFYPDVDDSAVVVMALHQAKLPNEELKKQAIDRALNWIATMQCKPGGW
AAFDLDNDQEWLNSVPYGDLKAMIDTNTADVTARVLEMLGACNLSIQPDNLEKSLDYLLK
EQEIEGCWFGRWGVNYIYGTSGVLSALALINPLKYARDINQGAAWLVKVQNSDGGWGETC
FSYNDPSLKGKGDSTASQTAWALIGLIAAGEATDKLAIDSIEKGINYLLETQKLDGTWDE
EYFTGTGFPCHFYLKYHLYQQYFPLMALGRYQAKCSS
>A0A6I6FMM7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces ficellus|TrEMBL
MTATTDGSTGALEPHAPSATRTTTTTTAASDVEDLAARAAQRSIDHLLARQDAEGWWKGD
LETNVTMDAEDLLLRQFLGILDEATARAAALHIRGEQREDGTWATFYGGPGVLSATVEAY
VALRLAGDAPDEPHMARAAARIREQGGIASARVFTRIWLALFGWWKWDDLPELPPELVFL
PSWFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFRLDELHTDPAVPNPPRPLAPAGSW
EGAFQRLDKALHAYHRVAPRWLRRAAMNTAARWIVERQENDGCWGGIQPPAVYSLIALHL
LGYDLEHPVMRAGLESLDRFAVWRDDGARMVEACQSPVWDTCLAVIALADAGVRPDHPAL
VKAADWMLGEEIVRPGDWAVRRPGLAPGGWAFEFHNDNYPDIDDTAEVILALRRVRHPHP
EQVEAAVRRGANWTAGMQSRDGAWGAFDADNTSPFPNLLPFCDFGEVIDPPSADVTAHVV
EMLAHEGKAHHPRTRRGIAWLLAEQEANGAWFGRWGVNHIYGTGSVVPALTAAGLPTSHP
AIRRAVGWLESVQNGDGGWGEDLRSYREQEWIGHGASTASQTAWALLALLAAGERDSKAV
ERGVRWLADTQAEDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPVVGRL
GKGA
>A0A7L5A8N9|squalene-hopene cyclase|EC 5.4.99.17|Granulicella sp. WH15|TrEMBL
MSAVNPINPGNEQAVNPSAKTTAQPRFGRIDLGLDRVVEGIDRARDWLMGQQHPDGYWCG
ELEADTMLESDYIFMHVLLGTGDRGKMERAVNEILRHQNEDGGWSIYPNGPSNISLGVKA
YFALKLMGWSQDHPVLVKARKWILANGGVTECNTFTKIYLCFMGQYEYDAVPAVPPEIVL
FPNWFYFNIYEISSWSRAILVPLSIAYSKKPFKKLPPEQGIDELFVGGRMNANLHLRWDK
NRPVGWRNFFLALDRIAHWAERVHIRPLRKMALKKAEKWLLERFEKSDGLGAIYPAMMNA
IIALKCLGYGTDDPQFIRAMDEFEKLGLDFPEGEPNYPTPTFRMQPCVSPVWDTAQAVFA
LGEAGLAKDDPRMVKAADWLLDKEVRQKGDWAFTVPNIAPGGWYFEFNNEFYPDVDDSAQ
VLMALNAVNHPKERKQIDASQRAIEWIFAMQCRNGGWASFDKDNTKKIFEYIPFADHNAM
IDPPTVDITGRILEMLAQYGYTRRDPRVEKAVQFCLKEQESDGSWFGRWGVNYLYGTFLV
LRGLEAMGYWNHEPAIQQAAEWIRMVQNSDGGWGETCGSYDDPNTRGIGPSTPSQTAWAI
LGLLAAGDTRSDSVAKGIRWLIDKQMENGTWPESAEGRNGEAIYTGTGFPRVFYLAYHLY
RDYFPLLALTTYRRAMEREAAAA
>A0A838UHS4|squalene-hopene cyclase|EC 5.4.99.17|Caulobacteraceae bacterium|TrEMBL
MDDASALHSTVNLDDAVNRAAAALAGRQKSDGHWLFELEADATIPAEYILLTHYLGEPAD
LDLERKIGAYLRRVQAAHGGWPLHHGGGFDVSATVKAYFALKMIGDDPAAPHMAAARQAM
LEHGGAGACNVFTRILLALFGAIGWRAVPRIPVEIIALPSWFPIHLSKISYWARTVIVPL
LVLRALKPQARNPRGVRIDELFTAPPAGLRGLPRGAHQKEPWASGFFLLDAVLRVVEPLF
PKAGRRRAIAKCEAFVTKRLNGEDGLGAIFPAMANAVMMYAALGIGADDPRRATARASIE
KLLVVREAEAYCQPCLSPVWDTALAAHALLEAGDPQSEASARRALDWLAPLQVLDVAGDW
AEQRPGVRPGGWAFQYRNDHYPDLDDTAVVVMAMDRAGPPGDFRQAIARGAEWVEGMQSA
NGGWGAFDADNTFHYLNNIPFADHGALLDPPTADVAARCVSMLAQLGESPSSPRMKAALA
YLAREQAADGSWFGRWGVNYVYGTWSALCALNAAGLTPDAPVVAKGADWLTAIQNGDGGW
GEGCDSYALDYAGYQPAPSVPSQTAWALLGLMAAGRADHPAVGRGIAWLAARQGADGGWA
EDAYTGGGFPRVFYLRYHGYRQIFPLWALAGYRNLIRGNSGRTGLGM
>E0UII0|squalene-hopene cyclase|EC 5.4.99.17|Gloeothece verrucosa (strain PCC 7822)|TrEMBL
MQIQARNISTKVTEVFSKVKEAIAASQQYLLSIQYPEGYWWAELESNVTITAEAVLLHKI
WGTDTTRPLHKVETYLRRQQREHGGWELFYGDGGDLSTSVEAYMALRLLGVSASDPALVR
AKAFILSRGGISKSRIFTKMHLALIGCYDWRGVPSIPPWIMLLPENFPFTIYEMSSWARG
STVPLLIVFDKKPVYQCGITLDELYSEGINHVRYDLPRNGDWTDVFVWLDGVFKFAETNN
LIPFRNESLKAAERWVLERQEDTGDWGGIIPAMLNSLLALRALDYEVNDPIVHRGFKSVD
NFAIETEETYHVQPCISPVWDTAWVLRALVESGLKPDEPVLVKGAQWLLDKQILDYGDWA
VKNKEGTPGGWAFEFDNRWYPDLDDSAVVVMALEQVKMPDEQLKYGAMRRCVRWMATMQC
KAGGWGAFDVNNDQNWLNYLPYADLKAMIDPNTADVTARVLEMLGTCELSMDHDRVKRAI
AYLEQEQEADGSWFGRWGVNYIYGTSGALSALAAIAPVTHQAQIEKGAAWLVGCQNPDGG
WGETCFSYNNPALRGKGDSTASQTAWGLIGLLAAGEATGKFAKTALERGVNYLLATQRPD
GTWDESYFTGTGFPCHFYLKYHLYLQYFPLIALSRYQRLLGFN
>A0A6N8DQ92|squalene-hopene cyclase|EC 5.4.99.17|Rhodoblastus acidophilus|TrEMBL
MNFASPVPRDNYTTALRSGVSAAVDWLVARQKPDGHWVGRAESNSCMEAQWRLALWFLGL
DDHPLCARLAQSLLDTQRADGAWEIYFGAPNGDINTTVEAYAALRCSGFSADHPALRKAQ
DWIEAKGGLKNIRVFTRYWLALIGEWPWEKTPNLPPEVIWLPLWFPFNIYHFAQWARATL
MPIAVLSARRPSRPLPPENRLDALFPEGRETFDYTLPAKPNPDFWDRFFRKTDEILHKLQ
GGWLGRAGLRNGAIRHVLEWIIKHQDADGAWGGIQPPWIYSLMALHVEGYALTHPVLAKG
LDALNDPGWRVDVGDATFIQATNSPVWDTMLTLLAFDDAEALDNEASDKAVDWLLSRQVR
VPGDWSIKLPGVKPGGWAFEYANNFYPDTDDTAVALIALAPFRSHDKWKARGIEEAIQLG
VDWLIAMQSKNGGWGAFDKDNTKKILTKIPFCDFGEALDPPSVDVTAHVVEAFGKLGLSR
EHPAMVRALRYIRDQQEPDGPWFGRWGVNYIYGTGAVLPALAAIGEDMSQDYVCRACEWI
VSRQQANGGWGESCASYMQAEGAGRGDATASQTAWALMALLAAKRPKDREAIERGCHFLL
ETQREGTWPEPHYTGTGFPGYGVGQTIRLNDPLLAQRLKQGPELSRAFMLRYGLYSHYFP
LMALARAIQRG
>A0A6A7M1I7|squalene-hopene cyclase|EC 5.4.99.17|Rhodospirillales bacterium|TrEMBL
MSTRAAIPDRTDLDRLEDDIDRAVQALMRRQRDDGHWVFELEADATIPSEYVLLRQYLGE
PDEPELERKIGAYLRRIQGEHGGWSLFHGGAFDISASVKAYFCLKMIGDGPDAPHMAKAR
NEILAHGGAEQANVFTRILLAQFGQLSWRRVPTMPVEIILLPRWFPIHLSRMSYWARTVI
VPLLVLAALRKRARNPRGVDIQELFATTSRSEPRLAAHQRRGWALFFKALDRLLKAGEGL
WPTTLRRRAVERCVGFVSERLNGENGLGAIYPAMANAVMMFDALGYPPDHPDYATARRAI
DRLLVVREDEAYCQPCVSPVWDTALASQAMLEVGGEAEAAARRGLGWLQPLQELDTRGDW
SERRPHVRPGGWAFQYRNAHYPDLDDTAVVVMAMDRARRQADAGSGYDEAIARGVEWIGG
LQSGNGGWAAFDVDNVDHYLNNIPFADHGALLDPPTADVSARCISMLAQLGETPANPVVR
AGLDYLEREQMADGSWFGRWGVNYIYGTWSALCALGTAGLNGTTPSVRRAADWLIAIQNA
DGGWGEDCTSYRLDYRGYEPAPSTASQTAWALLGLMAAEGVDHPAVERGIAWLRQRQDAT
GLWQQDAYTGGGFPRVFYLRYHGYPAYFPLWALARYRNRRRANNRRVAYGM
>A0A522VSF1|squalene-hopene cyclase|EC 5.4.99.17|Rhodospirillales bacterium|TrEMBL
MNVSAFRTSPDCQPSGPACHEEPMSLDAVERTIETVTEGILKRQKPDGHWVYELEADATI
PSEYIFLNRYLATPEPELEAKLARYLRAIQNEDGGWPLFHKGVSNISASVKAYYALKMVG
DDIDSAHMAKARACIHGLGGAEKSNVFTRFALALFGQVPWRAVPVTRPEAILLPEWFPFH
ISKVSYWSRTVMVPMFVLCALKPRARNAGGTGIRELFLADPEKIREWQNNPTGSRLGNFF
LVLDKFLRAIEFFFPKFLEKKSIAKCMDFVLTRLNGEDGLGAIFPAMANSVMAMDALGFS
RDDPNFKIARKSISNLVVEHGDTAYCQPCVSPVWDTGLAAHALLEAGLQGDHPAIAKAVG
WLKERQVLKVEGDWIWQRPGLRPGGWAFQYRNDHYPDVDDTAVVALALHRAQPGETQESV
ARAAEWVEGMQCGNGGWAAFDAENEKYHLNHIPFADHGALLDPPTLDVSARCLSLLAQLG
YDKSHPKVAAGLEYMRIEQEEDGSWFGRWGTNYIYGTWSALCAFNAAGEDMNAPHIRKAV
DWLKSRQREDGGWGEDCASYWDETKALCLESTPSQTAWALLGLMAAGEVDSPEVVRGIDY
LMKAPRDLYGKWHEERYTAVGFPRVFYL
>C5BPY1|squalene-hopene cyclase|EC 5.4.99.17|Teredinibacter turnerae (strain ATCC 39867 / T7901)|TrEMBL
MEIQDEVDLLEPQESLTASADSAVDRALFWLLDAQYEDGYWAGILESNACMEAEWLLCFH
VLGIANHPMSRGLVQGLLQRQRADGSWDVYYGARAGDINTTVEVYAALRCQGYAADHPDI
KRARDWIQLQGGVKQVRVFTRFWLALIGEWPWEETPNLPPEILFFPRWFPFNIYHFAAWA
RATLVPLCILSARRMVVPLNKKSCLQELFPEDRSAVVALGKKAGAWSTFFYHADRALKKY
QRTFKRPPGRQQAIKMCLEWILRRQDADGAWGGIQPPWIYSLMALKAEGYPVTHPVMAKG
LAALDAHWSYERPGGARFVQACESPVWDTLLSSFALLDCGFSCTSSSELRKAVDWILDQQ
VLLPGDWQQKLPTVSPGGWAFERANVHYPDVDDTAVALIVLAKVRPDYPDTARVNLAIER
GLNWLFAMQCRNGGWGAFDKDNDKDLLTKIPFSDFGETIDPASVDVTAHVLEALGLLGYR
TTHPAVAKALEFIRSEQENDGCWFGRWGVNYIYGTAAVLPALASLNMNMNQEFIRRAANW
ILGKQNNDGGWGESCASYMDDTQRGRGPSTASQTAWAMMSLLAVDGGTYAESLLRAEAYL
KTTQTPEGTWDEPYYTGTGFPGYGIGRREIKRQRSLQQHAELSRGFMINYNLYRHYFPLM
ALGRLAALRGA
>A0A6N6MX82|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium sp. YIM 132548|TrEMBL
MREAVNKVEALQRPKTQDISLEDVERGVASATRALTRLAQSDGHICFELEADATIPSEYI
LFHQFRATNPRPGLEAKIGHYLRRTQGKHGGWALVHEGPFDISASVKAYFALKMIGDDIE
APHMRRAREAILSRGGASNANVFTRFLLALYGEVPWRAVPVMPVEVMFLPKWFPFHLDKV
SYWARCVMVPMFVLQATKPRARNPRGIGVQELFVTPPDHVLTWPGSPHATWPWTPIFGGI
DRVLQKVEDYLPKKPRRRAKEKAVAWVSERLNGEDGLGAIFPAMVNTVLMYEVMGYPSDH
PQVRIACEAIEKLVVEKDHEAYVQPCVSPVWDTALASHALLEAGGLEAEHQARRGLDWLK
PRQILDIVGDWAARRPNVRPGGWAFQYANAHYPDLDDTAVVVMAMHRAMRQHGLVADMPD
YTTSIARAREWVEGLQSSDGGWAAFDADNNHMYLNHIPFSDHGALLDPPTADVTARVVSM
LAQLGETRESSKALDRGVSYLFKEQEKDGSWYGRWGMNFIYGTWSVLCALNAAGIDPQSP
EVQRAVAWLIRIQNPDGGWGEDASSYKIDPAFEPGYSTASQTAWALLALMAAGASNEPAV
TRGINYLARTQGGDGFWNEERYTATGFPRVFYLRYHGYSKFFPLWAMARYRNLKRSNTRQ
VAFGM
>A0A845QF69|squalene-hopene cyclase|EC 5.4.99.17|Pyruvatibacter mobilis|TrEMBL
MSVVEFGPDANGAASVDSPEARAAREELIRTQKDRLLDMQRDDGHIVFELEADSTIPSEY
VLLRHYLDEIDTAKEAKIGNYLRRIQNDDGSWPLFHDGDGDISATIKSYWALKLIGDDID
APHMVKARDWVLERGGAAKANVFTRIMLAIFKQIPWRGVPVIPVEVMLLPQWFPFHMSKI
AYWSRTVIAPLLILCSLKAEARNPTGIDIRELFVTPPEKEKVYNINPTGDFVGDCFLVLD
KVLRFCEPAFPKVLREKAVKKAVDFYTERLNGEDGLGAIYPAMANSVMAYDLLGYPKDHP
DLVIAKKSIENLLIETDDELYCQPCVSPVWDTCLASHALMEAGLEAGDEELDGALDWLKD
RQILDVVGDWSVRRPDVRPGGWAFQYNNDYYPDVDDTAVVAMAMHRTGKEKYAESIERAA
EWVIGMQSSSGGWGAFEPENEHFYLNSIPFADHGALLDPPTEDVTARCLSFLAQLDKERF
AKEIALGIGFLKREQQDDGSWWGRWGANYIYGTWSVLCALNAVGEDMTQPYIQRSVAWLK
ARQRPDGGWGEDLATYYEDRKSEVKESTASQTAWAVLGLMAAGEVDTDEVRKGIAYLDAA
KRDGARWEEKLYTGTGFPRVFYLKYHGYAAYFPLWAVSRYENLMKSNDRTVAYGM
>A0A388RJK1|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus sp. P-10|TrEMBL
MSMKETDFATTATPIQFAADPAFGPAAGPAAPQSAAQALDHGIGLAVDALLHQQRPDGHW
VYELEADATIPAEYVLMVHYLGEAPDLALEARIARYLRRIQNPDGGWPLFHEGRPDLSAS
VKAYFALKMAGDDPQAPHMARARQAIHAMGGAEASNVFTRTLLALYGVMSWSAVPMMPVE
IMLLPRWFPFHLSKVSYWARTVIVPLLVLNSLRPRARNPRHVGIDELFANQHHGAGLAPR
APHQHAGWYNVFRGLDALLRVAEPVFPRLLRRRAIAAAQTFVRERLNGEDGLGAIFPAMA
NSVMMFDVLGVPADDPARAVARRSVERLLVEHGDEAYCQPCLSPVWDTALAAHALLETGE
ARAAEAVGRGLEWLKPLQVLDVRGDWTVRRPRVRPGGWAFQYANPHYPDVDDTAVVVAAM
DRYMREHAAPGRYDEAAARAAEWIVGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDP
PTADVSARCLSMLCQIGATPARSEPAARALRYLLAEQMADGSWFGRWGTNYIYGTWSALC
ALNAAGMGSDAPAVRRATEWLAGIQNEDGGWGEDGSSYRLDYRGYETAPSVASQTAWALL
ALMAAGAVQHPAVARGIGYLLRTQRPPQEGGLWQEPRFTAVGFPRVFYLRYHGYARYFPL
WALARYRNLQRGGGGRVTWGL
>A0A6M8H754|squalene-hopene cyclase|EC 5.4.99.17|Lichenicola cladoniae|TrEMBL
MVLGTVQEREAVVFDETAEPSDTVLSRAIDRGRSALGRRQQPDGHWLFDLEADATIPAEY
LLLEHYLDRIDPAVEARIGVYLRRIQGTHGGWPLYYEGRFDLSASVKAYFALKMLGDDPD
APHMVRAREAILAAGGAERSNVFTRFQLALFGEVPWHGVPCMPVEIILLPKWFFFNIWNM
SYWSRTVVTPMLVLGALHPRARNPRGVRVQELFRVPPSEVRDWIRGPYRSAWGPVFKAID
SLIRPFDRRMPAAVRNHAIGVARSFIETRLNGLDGLGAIYPAMANTVMMHDALGVPADHP
DAAMAWEAIRRLLVDQGDETYCQPCVSPIWDTSLAGHAMAEADMDGPPEEGVLPVPAALD
AASAWLRERQVLDVKGDWAIRNPTLDPGGWAFQYNNAYYPDVDDTAVVGMLLHRHDADGN
VEALVRARRWIIGMQSTNGGWGAFDIDNDTQILNHIPFSDHGALLDPPTADVTARCLSFL
GQLGHIEDRPVIDRGIAYLRREQEPDGSWFGRWGTNYIYGTWSVLCALNAVGVSPADPMV
VRAVNWLVSIQQPDGGWGEDCATFEGAEPGRYHASLPSQTGWALLGLMAAERRDHPAVAR
GIAMLTATQEADGEWQEQPYNAVGFPRVFYLRYHGYRLFFPLMALSRYRNLGRSNSSRVS
HGF
>A0A7V8ST61|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. AJS327|TrEMBL
MTATTDSAPETDSPATLAERAASRAVQHLLERQDDAGWWKGDLETNVTMDAEDLLFREFL
GIRDERGTVAAARFIRARQRADGTWPVFHGGPGDLSVTVEAYAALRLAGDAPDAPHMARA
AAWVREHGGVARTRVFTRIWLALFGWWPWDQLPEIPPEMIFLPRWFPLNIYDFGCWARQT
IVPLTVVAAYRPVAPAPFGLDELHRDPNRPVPPGHRAPLASWDGAFQRIDGALRGYRRVA
IRPLRRAALKAAARWIIERQENDGAWGGIQPPAVYSLIALRLLGYDLDHPVMRAGLASLD
RYAVWYPDGSRMVEACQSPVWDTCLSVIALADAGVERDHPALLRAADWLLGEQVTRTGDW
SVRKPQLPPGGWAFEFHNDTYPDVDDTAEVCLALRRVDHPDQRRVDEAVTRAVRWTVGMR
SRDGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTAHALEMLAAERRAGEPAARRAV
SWLLAAQETDGSWFGRWGVNYLYGTGAVLPALVAAGIPTGHPAVRRAVRWLESVQNEDGG
WGEDPRSYTDGHWAGHGGSTASQTGWALMALLAAGERASAATERGVTWLAEAQHEDGGWD
EPQFTGTGFPRDFSINYHLYRAVFPLTALGRYLHGDRPAPRTP
>A0A7K2SXW3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8350|TrEMBL
MTATTDGPAGAAELSATTAGHPDRTTLAPDEVLAAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPSDLSATIEAY
VALRLAGDAPDAPHMARAASWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFL
PSWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPARPNPSRKLAPAASW
DGLFQRLDKGLHLYHKIAPRPLRRIAMNVAARWIVERQENDGCWGGIQPPAVYSLIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMVEACQSPVWDTCLATIALVDGGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARVEAAIERGVRWNLGMQSRNGAWGAFDADNTSSFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGRARHPRTRRGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALIAAGLPAAHP
SVRRAVEWLESVQNDDGGWGEDLRSYREEKWIGHGESTASQTAWALLALLAAGRRDSVAV
TRGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRM
GAAQGA
>A0A371PP42|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus paeoniae|TrEMBL
MSNLRHRVDHSIGQLVDWLIEEQKEDGSWRFCFENGIIIDAYVLILFRLLEHEDEPFMRA
LHDRIAACQQSDGGWRLYRDEEEGSLSASVEAYYAMLLSGYSHADDEHMQRAKAYILSRG
GIGMVKSTLTKTILAATGQRDWPLSISSIPMEVLLVPSELPLSLFSFSGYARVHLVPMLV
MGSRKFSLRTARTPDLSPLYAHRDALDDACLPSHIAMRTQIGIGIDRLIGSPRSLRDAAT
DKAEAFMLERIEDDGTLYSYATSTVFMIFALLALGYGKEHPVVRRACQGLSDMRFNTGGY
TTIQNSPSEIWDTALLTYALQEAGVSSHEAVIRKAGAYLLSKQHTRRGDWSKHNPNTPPG
GWGFSETNTMNPDVDDTTASLRAIRQLASDDPVYAEAWNRGLQWVTSMQNRDGGWPAFEK
ETNNQMLTWLAIEGAKSAAIDPSEADLTGRTLEYLGHFAPQQTNEKYMKRGIEWLIRNQQ
KNGSWYGRWGVCYLYGTWAALTGLVAAGLPASHHSIKNGAEWLLRMQQSDGGWGESCRSD
SKSHYVSIGASTPSQTAWALDALIAISPEATPAIHRGIERLIAFLPESNWTTDYPTGSGL
PGYFYIHYHSYRYIWPLVALAHYKQKFGS
>A0A5B9GI71|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter oryzoeni|TrEMBL
MAADGSALSESRLSSEALDRAVLSAHTALSQAQQDDGHWVYELEADATIPAEYILLEHFM
DRIDDALEQKIAIYLRRIQSEEHGGWPLYHNGKFDLSATVKAYFALKAVGDDINAPHMQR
AREAILDHGGAERSNVFTRSQLALFGEVPWRATPVMPVELMLLPAKAFFSVWNMSYWSRT
VIAPLLVLAALRPVAANPRQVHVRELFVTPPEKVQDWIRGPYRSAWGYVFKGLDSVLRPV
VPFIPEKTHKKAIQAALDFIEPRLNGKDGLGAIYPAMANVVMMYRAMGVPDEDPRAKTAW
EAVQALIVEKDDEAYCQPCVSPIWDTGLSGHAMIEAASGPDGIAPEKTLSKLKTACAWLR
SKQILNVKGDWAVRNPNLAPGGWAFQYGNDYYPDVDDTAVVGMLLHREGDPANADSIERA
RTWIVGMQSTDGGWGAFDIDNNKDVLNHIPFADHGALLDPPTADVTARCISFLAQLRNPE
DEPVIQRGLEYLRKEQEKDGSWFGRWGTNYIYGTWSALCALNAAGVSHDDPAVVKAVEWL
RSVQRADGGWGEGCESYEGGPHGTYGESLPSQTAWAVLGLMAAGRRDDPAVARGISWLAD
QQDANGEWHEDPYNAVGFPKVFYLRYHGYKQFFPLMALARYRNLENSNSRRVSFGF
>A0A3R9V6G8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. WAC05292|TrEMBL
PRTYAPLATWDGLFQRMDRALHLYRRFAPRPLRRAAMDAAARWIIERQENDGCWGGIQPP
AVYSLIALHLLGYDLGHPVMRAGLESLDRFAVWREDTAPGPDGLPAGPAPVRMVEACQSP
VWDTCLAAIALADAGLPPDHPALVKAADWMLGEEITRTGDWAVRRPGLAPGGWAFEFHND
NYPDIDDTAEVVLALRRVAHPDPDRLDAAVDRAVTWTLGMQSGDGAWAAFDADNTSTLPN
RLPFCDFGEVVDPPSADVTAHVVEMLAAEGRAHDPRTRRGIAWLLDRQEPDGSWFGRWGT
NYVYGTGSVLPALAAAGIPASHPAVRRAVAWLESVQNDDGGWGEDQRSYQDPGTWAGRGA
STPSQTAWALMALLAAGERGGKAVERGIAHLVRTQLPDGTWDEPHFTGTGFPWDFSINYH
LYRHVFPLTALGRYLYGEPFAPGTP
>A0A7V9MVK8|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MNQLNPGDFVEVEGAIGAATYAILAQQRPDGHWVYELEADATIPAEYVLLVHYLAEAPNL
ELERKIGVYLRRIQGAHGGWPLYHEGAFDISATVKAYFALKMIGDDINAPHMARAREALH
ARGGAIKANVFTRILLALYGQCSWNDVPTVPPELILLPRWFPVHLSKMSYWARTVIVPLL
VLCAKQPLAKNLRGIHIDELFVPGVPAASPRAPHQSAGWSAFFGALDRVLKTVPWPKDSR
DKAIEKCREWTRLRLNGEDGLGAIYPAMANSVMMYDVLGYPPEHPDRAIARKSVENLLVI
KEHEAYCQPCVSPVWDTALVAHALLETKDAAAEAAVARGLEWLKPLQVLDVKGDWAGEKP
DVRPGGWAFQYRNDHYPDLDDTAVVVMAMDRAAQRGEYKEAIARGAEWVEGLQSRDGGWG
AFDADNSYYYLNNIPFADHGALLDPPTEDVSGRCVGMLAQLGAKTDDPRLKAGIDYLIKT
QRGDGSWWGRWGVNYIYGTWSALAGLNGAGLGPDHATMKKGADWLLAIQNPDGGWGENCD
SYKLDYKGYEAAPSTASQTAWALLGLMAAGAVDHPAVARGVNYLKATQEGDGLWSQPHYT
GGGFPRVFYLNYHGYPKFFPLWALARYRNLKTGNSRRVEYGL
>A0A537UWG6|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MTQGMTARAKNEPIVSLALHVPGLNDAIGRAAASLLSLQREDGHWVFELEADATIPAEYV
LLQHYLGTPEPDLERRIARYLQSTQAEHGGWPLFHGGEFDLSATVKAYFALKAAGDPIDA
PHMQRARAAILARGGASRCNVFTRILLALFGEVPWNAVPVMPVEIMLLPSWFPFHIDRIS
YWSRTVLVPLLVLMALRPKARNPNGIRIPELFVEPPETVRHWILPATPSATGYAFTLLDR
IVRLAEPMFPAEPRRRAIEKAVTFVTERLNGEDGLGGIFPAMANSLMMFDCLGYPPDHPD
RVAATAALRKLVVDNGEQAYCQPCLSPIWDTALACHALMEVGETRLTPAVRQALDWLAER
QVLDRVGDWAIARPGLRPGGWAFQYANPHYPDLDDTAAVALALDRFDGAAYEPGIDRAAE
WILGMQSRNGGWASFDADNTHYYLNHIPFADHGALLDPPSADVSARCLGFLAQRGFSPDH
PAVAGALDFLRREQEADGSWFGRWGTNYIYGTWSVLAALNAIGLDPASPEIRRAVVWLLS
YQRADGGWGESGESYWPDKPHGEAPDSTASQTAWALLALMAAGEVAHPAVARGIAYLIES
QDRDGNWNEPWYTAVGFPRVFYLRYHGYRAFFPLFALARYRRLSLANSRRVAFGL
>A0A2Z4IVC7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces cadmiisoli|TrEMBL
MTATTDGSTGALPPRAAAASETESITPVAAGVEQAAAHATRRATDHLLSRQDAEGWWKGD
LETNVTMDAEDLLLRQFLGVRDEATTQAAALFIRGEQREDGTWATFHGGPGELSATIEAY
VALRLAGDEPDAPHMAEASQWIRDRGGIAAARVFTRIWLALFGWWKWEDLPELPPEIIYF
PKWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPAVPNPVRPLAPAATW
DGAFQRLDRALHVLRKVAPRGLRRAAMRAAARWIIERQENDGCWGGIQPPAVYSLIALHL
LGYDLRHPVMRAGLESLDRYAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHPQL
VKAADWMLGEQIVRPGDWSVRRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHDQ
ERVDRAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLALEGLAHDPRTRRGIQWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALVAAGIPGSHP
AVRRAVTWLEKVQNDDGGWGEDLRSYDDARSWSGRGASTASQTAWALMALLAAGERDSKA
VERGVAWLVATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHAEPLAQA
RGSG
>A0A7C5Z099|squalene-hopene cyclase|EC 5.4.99.17|Acidobacteria bacterium|TrEMBL
MTQEAGIEIESSKNDRAVGVVGAELDLRVRKAVERATQYLLSLQAPEGYWVGELEADTTL
ESDYVFFLHVIGKFEPERVAKLANYIRRNQLPDGGWNIYKGGPSELNATVKAYVALKLAG
DSPNDPHMAAARRKVHELGGLEQTNSYTRFYLALGGAVKWNYVPAIPPELMLPPSWFFFN
IYSLSSWTRAIVVPLTILYAMRPQWPVPEHARVDELFCDSSGHIPAFDWDRKIFTWRNLF
LAIDRLFKLHESLPWKPFRRVALRRAQEWMLEHLERSEGLGAIYPAMVNSIFALLAMGHP
ADDPLTAREIGHLADFEIETSDTIRLQPCVSPVWDTAIVMYSLEEAGLPPDHPALIKAAR
WLLDRQIVGPGDWQVKNKDAAPGGWAFEFRNDFYPDVDDTSFVMMALQRVAYPEKERMKR
ALERGFQWLVSMQNRDGGWGAFDKNNDCVVLTRVPFADHNAMIDPSSVDVTARVLECIGR
FGWPASHPAVQRALDFIRREQTKEGAWYGRWGVNYVYGTSGVLRMLEVFGLSQSPEAQRG
ADWLRSVQGHAGGFGESCASYDDPALKGRGAPTPSQTAWGLIGLLATRGASDPAATRAVQ
YLLDCQTEEGFWNETEFTGTGFPRVFYLCYHLYRDSFPLYALARYLNLRGGNNNSEFIRF
SPSESAPHNGNGKRNGRASS
>A0A3M0YJN2|squalene-hopene cyclase|EC 5.4.99.17|Cyanobacteria bacterium J149|TrEMBL
MTAQLTNPNKVEHSKVKSGIKQAQDYLFSLQEKDGHWCAYLESNVTLTAEAVLLYKIWGI
DSHKPLHKIEHYLRSQQREHGGWELYYGDGGDLSTSVEAYMALRLLGVAQDDEALIKGKR
FILSKGGISKSRIFTKFHLAIIGCYDWRGVPSIPPWIMLLPQNPIFTIYEMSSWARSSTV
PLLIVFDQKPVFKIEPKINLDELYSEGKENVRYELPRSGDWTDIFVQLDNLFKFAEDINF
VPFKEESIRAAEKWIIEREEVTGDWGGIIPAMLNSLLAFKTLNYHVNDPMVARGLEAVEN
FAIETHDDYLVQACVSPVWDTAWCLRALVESGVAPNHPALVKGGEWLLDKQILDYGDWIV
KNPHGKPGGWAFEYENRFYPDMDDSSVVIMTLHQLELPREDLKKEAILRCLRWIETMQCH
NHGWAAFDINNDANWLNLLPYADLKAMIDPATADITARVLEMVGSCDLPMSSSKIQKAIA
FLLHQQENDGSWFGRWGVNYIYGTSGALSALAVIAPQTSQEAMKKGINWLINCQNPDGGW
GETCDSYKNPALKGKGNSTASQTAWALIGLLDAGKALGKFEQDSINKGINYLLSSQTEIG
TWEEKEFTGTGFPQHFYINYHLY
>A0A3N5Q990|squalene-hopene cyclase|EC 5.4.99.17|Xanthomonadales bacterium|TrEMBL
RPDGSWEAYYQAPQGDINGTVECYAALRCVGFRPDDEPLVRARRWIFEHGGLRGIRVFTR
YWLALLGEWPWSATPNLPPEVIANPRHWFVFDIYNFASWARATLLPLAVLSARRAVRPLP
PGRRLDELFPEGRERMDYSLPRRGPWFSWRRVFLFSDRILHLYQQLGFTPFRETAINACL
GWIVRHQDADGAWGGIQPPWIYSLMALNVEGYELTHPVISKGLTALDSHWSYERGGTLHI
QASESPVWDTLLALLAMQDCEREFTPAMTRALDWVLANEVRYPGDWTKKVKNVEPSGWAF
ERANLHYPDIDDTAVALIVLSRLPRQLLDEPRIRATIDRALAWTLAMQSSNGGWAAFDKD
NDRPIITKIPFCDFGEALDPPSADVTAHVLEALGLLGFDRHHPAVARGYRFIRSEQETDG
SWFGRWGVNHIYGTAAVLPALAAIGEDMTQAYVRAAADWLVAHQNTEGGWGETCASYMDD
SLRGRGPSTASQTGWALLALVATGSRDYERSIRRGVGFLIDSQRDDGTWNEPYYTGTGFP
GYGFGARMDFRDQKTRERIAQGTELQRGFMINYNLYRHYFPLMALGRARKFLGA
>A0A4Q1S4V9|squalene-hopene cyclase|EC 5.4.99.17|Geobacillus sp. PK12|TrEMBL
MVDDERRVLIDALKQSQAADGSWRFPFETGISTDAYMIILLRTLGIHDEPLIQALVERIE
SRQDPNGAWKLFADEGDGNVTATTEAYYALLYSGYRKKNDPHMQKAKARILEMGGLERVH
LFTKVMLALTGQHPWPRRFPLPLEFFLLPPSFPLNMYDLSVYGRANMIPLLVAAERRYSR
RTAKSPDLSDLVVSRNDWRLPESRSLWSYIKRSLIGLPDQLHHAAEQRAVRYMLDHIEPD
GTLYSYFSSTFLLIFALLALGYPKDDPYIQRAIRGLRSLRTEIDGHTHMQYTTASVWNTA
LASYALQEAGVPLTDRTIEKANRYLLSRQHIRYGDWAVHNPYGIPGGWGFSDVNTMNPDV
DDTTAALRAIRRAAAKETAFRHAWDRANQWLFSMQNDDGGFAAFEKNVGKRFWRYLPIEG
AEFLLMDPSTADLTGRTLEYFGTFARLTKDHPAVARAVDWLLDHQEADGSWYGRWGICYV
YGTWAAVTGLSAVGVPIDHPAMQKAVHWLLSIQNADGGWGESCKSDGAKRYVPLGASTPV
HTAWALDALIAAAERPTAEMKAGVRALIRLLRHPDWTASYPAGQGMAGAFYIHYHSYRYI
FPLLALAHYEQKFGPFVD
>A0A7Y5Q4Q0|squalene-hopene cyclase|EC 5.4.99.17|Armatimonadetes bacterium|TrEMBL
MEQQAAALAFDFERGLNASIQQAQGWLVEHQDPAGFWVAPLESNASMEAEWILAMHFLGV
TNDPKQPGVVRAILNDQRPDGAWHNYHDAPDGDISTTVECYAALRAAGHHPDAPHLVAAR
EWILAHGGLPRVRVFTKFWLALIGEWPWDGTPSLPPELIFMPRWIPFNIYQFSSWARGTM
VPLSILAARRAVRPLPPSQRLDELFPGGREAMDYSLPRRGPLLSWERVFYTLDRLACLYQ
KLPVQPRREAAIKLCLEWIIERQEADGCWGGIQPPWVYSLMALNVEGYAVDHPVVAKGLD
AFGHPWSYERDGGLYVQACMSPVWDTVLALLALADCGEDCRSLPAVQRAVHWVLEEQIRT
PGDWRVYARGIRPGGWAFEFENDTYPDVDDSAVALLVLARLRDSSPDRNTVDEAIERGLE
WVLGMRCRNGAWAAFDKDNTNALVARIPFCDFGEALDPPSVDVTAHVVEALGHLGRDLSD
PVVSRAVDYIQAQQELDGSWFGRWGVNHIYGTAAVLPALRAVGEDMRAPYIQRAAAWIVA
HQNDDGGWGETCASYMDTSLRGVGVSTASQTAWALMALLAVGSRRYDEAIRRGADYLVLN
QREDGTWDEPEYTGTGFPGYGCGARVDLSRPGTTLPQGKELGRAFMINYNLYRHYFPLMA
LGRAREHLVPIHMAEAAD
>A0A8B6MA77|squalene-hopene cyclase|EC 5.4.99.17|Methylocella tundrae|TrEMBL
MEGKFGSAVADEGEAPGLALGQIEAAISRAQKALLGQQRPDGHFVFELEADVSIPAEYIL
FRHFLGDPADAELEEKIAVYLRRHQTADDGWPLFAEGAFNTSSSVKAYFALKMIGDSPDA
PHMKRARAAILKHGGAANTNVFTRSLLSLYGATPWRSVPVMPVELMHLPRWFPFHLSKIS
YWARTVLAPLVVVHALKPKARNPRNVGIEELFIEPADQVRRWPGAPHQTFPWTMIFGGID
HVLRWLEPYFPKRSQKRAIDKAVAFVTERLNGEDGLGAIYPAMAYSAMMFHALGVPASDP
RMIQVRKAIDGLLIIRADEAYCQPCVSPVWDTALASHALMESAGAGAKTPGEQTGASVRE
ALSWLAPRQVLDVAGDWATQKPHVRPGGWAFQYANPHYPDLDDTAVVVLAMDRAAKTLPG
GGKDASYDEAISRAKEWILGLQSANGGFGAFDADNDREYLNAIPFADHGALLDPPTADVT
ARCVSMLAQLGETARANPALASAVDYLIEEQEEDGSWFGRWGMNYIYGTWSVLSAFNAID
ADRGLEAVQKAAAWLKRIQNADGGWGEDGESYALEYKGYEPAPSTSSQTAWALLGLMAAG
EVDSQEVAKGLRYLTKTQAGDGFWTENRFTATGFPRVFYLRYHGYSKFFPLWALARYRNL
KSGNRLTTQFGI
>A0A7Y9HGD6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces fulvorobeus|TrEMBL
MTATTDGSTGAADLRAAPAGEPTDTTTAADDVLAAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPATIEATARFIRGEQLGDGTWATFYEGPGDLSATIEAY
VALRLAGDRPQDPHMVRAAGWVREQGGIAGARVFTRIWLALFGWWKWDDLPELPPELMFL
PPWVPLNIYDFGCWARQTIVPLTIVSATRPVRPAPFALDELHTDPACPNPPKPLAPPMSW
DGIFQRLDKAMHLYHRVAPRGLRRFAMNLAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLGHPVMRAGLASLDRFTVWREDGARMVEACQSPVWDTCLATIALADAGLSPDHPAL
VKAADWMLGEEIVRPGDWSVRRPRLAPGGWAFEFHNDNYPDIDDTAEVVLALRRIRHPDP
VRVEAAIERGVRWNLGMQSRNGAWAAFDADNTSPFPNRLPFCDFGEVVDPPSADVTGHVV
EMLAFEGMSRHPGTRRGVEWLLAEQEASGAWFGRWGVNYIYGTGSVVPALVAAGIPAHHP
SVRRAVSWLESVQNDDGGWGEDLRSYQEEKWIGHGPSTASQTAWALLALLSAGERESRAV
RRGVTWLAGAQQPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRA
LFRKGA
>A0A3N8CA68|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp9126|TrEMBL
MNPIPFFSPSALDAAIVRGRDALAHLQQPDGSWCFELESDATITAEYILMMHFMDKIDDV
RQAQMARYLRTIQRLDTHGAWDLYVDGAPDISCSVKAYFALKAAGDSEHAPHMVRAREAI
LKLGGAARSNVFTRILLATFGQVPWRATPFMPIEFVLFPKWVPISMYKVAYWARTTMVPL
LVLCSLKARARNPRNVSIRELFVTPPDEERRYFPPATGMRKLFLAMDRIVRHVEPLLPKR
LRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMAVLGYPDDHPLRRDCENALEKLL
VTRADGSMYCQPCLSPVWDTAWSTMALEQARGASAATQDTRVPDHELDARIARAYDWLAT
RQVNDLEGDWRENARRGTQPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRAQARASGKDP
YAERVARALDWMRGLQSRNGGFGAFDADCDRLYLNAIPFADHGALLDPPTEDVSGRVLLC
FGVTRREEDKAARARCIEYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALSGEDKSQPY
IVRALDWLRARQHADGGWGETNDSYADPHLGGTNYGESTSNYTAWALLAQMAFGDWQSDS
VRRGIAYLLSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLAGAQPA
PPARDPGTANAIADQAVA
>A0A6B8KH47|squalene-hopene cyclase|EC 5.4.99.17|Methylocystis heyeri|TrEMBL
MTTAEAPVLSVPSAPADPLEASVERARDALLALGKSDGHWCFELEADCTIPAEYVLMRHY
RAEPVDAELEGKIANYLRRVQGAHGGWPLFQDGDFNISASVKAYFALKMIGDDIDAPHMA
RAREAILRHGGAATSNVFTRALLALYGEIPWRGVPVMPAEIMLLPKWFPFHLDKVSYWAR
TVLAPLLVLMAKKPRAKNPLGVHIAELFVTPPDEVREWPKGEHQTFPWTAIFGTVDNILR
VVEPFFPKATRELSIARAESWTTERLNGVDGLGAIFPAMVNSLLMYDVLGVPAGDPRVVA
ARKSIELLLVVKEHEAYCQPCVSPVWDTALACHALMEAGGVESRVKQALDWLAPLQILDV
KGDWAVQRPDTPPGGWAFQYANPHYPDVDDTAVVVTAMDRYSRESGDAPYGERMERGRIW
VEGLQSKNGGWGAFDADNAYHYLNHIPFADHGALLDPPTADVSARCVSMLAQLGETPDTS
AVLFRGVQYLLSEQMPDGSWFGRWGANYIYGAWSSLCALNAAGLPHDHEAYRRGVAWLQS
IQNPDGGWGEDLSSYKLDYKGYEPAPSTASQTAWALLALMAAGERDCEAATRGVDYLLRT
QAEDGLWEEARFTATGFPRVFYLRYHGYAKFFPLWALARYRNLRETNARTVTVGL
>A0A6N1YDH4|squalene-hopene cyclase|EC 5.4.99.17|methanotrophic endosymbiont of Bathymodiolus puteoserpentis|TrEMBL
MFTENYNNMINTRTLECAIQVAQDKLLSLQHKDGYWIFELEADCTIPAEYIMMMHYLDDI
DAKLQAKIANYLRANQAKDGSYPLFHGGTGDISCSIKVYYALKMAGDQPEQPHMARLRDY
ILSQGGAAKANVFTRIALAIFEQLPWRGVPFIPVEIMLLPKWFPFHIDKVSYWSRTVMVP
LFILCTLEAKAKNPLNIDILELFITHPDKEQHYFSERGLLNKFFLFLDALGRKSRVLVTD
KMHRRAVDKALTWFTERLNGEDGLGGIFPAMVNAYEAMLLLGIPADDERVITARKAIDKL
LVIKEDEAYCQPCLSPVWDTGLTLLALQEVNLSGSKAYRERAYTWLKTKQLSDEPGDWRI
QRPNLAGGGWAFQFENPHYPDVDDTAVVAFGMATSDLPDMDESIHRATRWIAGMQASNGG
YGAFDVDNIYYYLNEIPFADHGALLDPPTVDVSARCVMLMAKVSQGHEEYLPAYQRCINY
IRSEQEADGSWFGRWGTNYIYGVWSVLMALEHTDISKSDPMYTKATHWIKSVQNKDGGWG
EDNQSYEDESLRGQFHTSTAFQTAWALLALMAAGETDTQEVKAGISYLLNSQTEEGVWAD
ECHTAPGFPRVFYLKYHGYDKFFPLWALARYRNEQNKT
>A0A849MXK0|squalene-hopene cyclase|EC 5.4.99.17|Roseicella sp. DB1501|TrEMBL
MQDLAAAAARPDFALAEGLIEGHSGTALDSAIGRATDHLLRCQQADGHWVFELEADATIP
AEYIMLRRFFGRRDPAREARIGRYLRRIQAQETRTAGGGWPLFHGGPLDVSCSVKAYFAL
RLIGDAPEAPHMARARAAILAAGGAERSNVFTRATLALFGEVPWHAVPVMPPEICLLPRW
FPFHLSKVSYWARTVLVPLTVVMARRPTPLVPTGVSLRELFRTPPERVRRWPGGAHAAEP
WKTLFAALDWVLQRTQHHFPAGARARAEAKAEAFVTERLNGEDGLGAIYPAMANAIWMYH
CLGVPEDDPRVVTAWSAVEKLVLDRPEAGTPEENPGESYVQPCLSPIWDTALVSHALLET
GDPRAEAAVTRGLSWLLDRQITDVAGDWAEARPGVAPGGWAFQYANPHYPDVDDTAVVVL
ALDRAERQIGPAGRRMAEAVSRATNWVVGMQSKGGGWGAFDADNTHHHLNSIPFADHGAL
LDPPTSDVSGRCLAMLAQLGHGPDHPAVRSAIDYMLAEQEPDGSWYGRWGVNYVYGTWSA
LTALNAAGLAPEHPAMRKAVAWLKARQNADGGWGEDGFTYPRCGGTRADTDLAMGPSTAS
QTAWALLALMAAGAVDDPAVERGAQWLMRQQRADGDWPEEDYTGTGFPRVFYLRYHGYAR
LFPLWALARLRNLRRGNSRQVMHGL
>A0A7Y9JIC3|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura luteofluorescens|TrEMBL
MTTTDVSGLTDAAAAAVEAARDHLLGLQSPEGWWKGELETNVTMDAEDLLLRQFLGIRSD
ADTKDAARWIRSRQRDDGTWANFHGGPADLSTTIEAYVALRFAGDPVDAGHMRRAAAYVR
EAGGIEGSRVFTRVWLALFGQWSWDDLPVMPPELVLLPSRVPLNVYDWACWARQTIVPLT
ILGSLRPVRALPFDLPELRRGVMPARDARGWGAAFNALDRVLHVYEKRPVRPLRRAALRR
AADWIIARQEADGCWGGIQPPWVYSLMALHELGYGLDHPVIRRGLDGLERFTIRDGRGRR
LEACQSPVWDTVLAMNALADAGVAADHPALLRAAEWVAGEEVRGPGDWAVKRPDVPPGGW
AFEFDNDVYPDTDDTAEAILALRRVALPEAEEPIRRAVRWLEGMASRDGGFGAFDADNTR
ELCTKLPFCDFGAVIDPPSADVTAHVVEALSKEGLAESAVVRRAVVWLLRAQEADGSWFG
RWGANHVYGTGGVVPALVAAGVGPGKPAIRRAVVWLEDHQNPDGGWGEDLRSYDDPAWIG
RGESTPSQTAWALLALLAAGERTPAVEAGVRWLVEHQRPDGTWDEDLFTGTGFPGDFYIN
YHLYRLVFPVSALGRYLDGAA
>A0A7W1ZS30|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia bacterium|TrEMBL
MFRKLRGVSVQVSKTDRAVKQEITTASVLHPFDDLETAIKRSQNYLLSEQKPEGYWIGEL
MVDSTLVSDTIAYHHWNGKIDQEWQRKAVNHIFSMQLPDGGWNIYYGGPAEVNATIKAYL
ALKLAGISVTDPRMLKAREVALNLGGVPRMNTFSKLYLALIGLYPWDYVPTIPSEVILIG
KWFHVNFHEMSNWSRAMLVPLALINHFKPTRNVHVTLDELYREGFHERDLMLPPDPDRVT
WRNFFLWLDKLHKFVENNNLRPFRKFALKKAEKWMLERFEGSDGLAAIFPAMLNSLIALK
ALGYADDHPLVLRAERELKRLEHETEDTVRIEPCLSPVWDSAIVAICLAESGVPADHPQM
KKACDWIIDKEIRFRGDWIYKNQANVEASGWVFEFNNKWNPDVDDTAMVLLALRKIPTDD
QQRRDECFKRGLNWMMTFQCKDGGWAAFDKDCTKSILEKVPFADHNAMLDPECADITARI
LELLGYEGYSLSHPQVQRAVQYVKNQQEEDGSWYGRWGVNYIYGTWAVLRGMRALNYDMS
EPWLLKAKAWLESVQHEDGGWGERCNTYDDPVFKGKGPSTASQTAWAVMGLCAFDDPKNE
SLKNGIEYLTRTQNPDGSWTELETTGTGFPRVFYLKYDMYRNSWPLLALASYKRLLPKGI
KRDQEASV
>A0A5M8ZGD2|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter sp. DmW_136|TrEMBL
MNMASRFSLKKILRSGSDTQGTNVNTLIQSGSSDIVRQKPAPQVPADLSALKAMGNSLTH
TLSSACEWLMKQQKPDGHWVGSVGSNASMEAEWCLALWFLGLEDHPLRPRLGKALLEMQR
PDGSWGTYYGAGSGDINATVEAYAALRSLGYAEDDPTVSKAAAWIISKGGLKNVRVFTRY
WLALIGEWPWEKTPNLPPEIIWFPNNFVFSIYNFAQWARATMMPLAILSARRPSRPLRPQ
DRLDALFPGGRENFDYELPTKEGRDVIADFFRMADKGLHWLQTSFLKRAPSREAAIKDVL
EWIIWHQDADGGWGGIQPPWVYGLMALHGEGYQFHHPVMAKALDALNDPGWRHDKGDASW
IQATNSPVWDTMLSLMALHDANAEERFTPEMDKALDWLLSRQVRVKGDWSVKLPNTEPGG
WAFEYANDRYPDTDDTAVALIALASCRNRPEWKAKGVEEAIGRGVRWLVAMQSSCGGWGA
FDKDNNKGILAKIPFCDFGEALDPPSVDVTAHVLEAFGLLGLPRDLPCIQRGLAYIRKEQ
DPTGPWFGRWGVNYLYGTGAVLPALAALGEDMTQPYISKACDWLINSQQENGGWGESCAS
YMEVESIGRGTTTPSQTAWALMGLIAANRPQDYDAIAKGCRYLIDLQEEDGSWNEKEFTG
TGFPGYGVGQTIKLDDPAISKRLMQGAELSRAFMLRYDLYRQLFPIIALSRASRLIKIGN
>A0A6G3PEN9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID10692|TrEMBL
MTATTDGSTGAANPARATAHGPTDTTTSADDVTAAARRAAERSIEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDADTTRAAALFIRGEQLGDGTWNTFYGGPSDLSATIEAY
VALRLAGDRPDEPHMARAAGWILEQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFL
PTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTNPDHPSPPRKLAPPTSW
DGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVMKAGLDSLDRFAVRREDGARMVEACQSPVWDTCLATIALADAGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARVEAAIARGVRWNLGMQSRNGAWGAFDADNTSGFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLARHPRTREGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALIAAGLPAGHP
AVRRAVSWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDTPSV
ARGVRWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRFVHGDPFADRA
DAVEGA
>A0A4R4M990|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. KC216|TrEMBL
MTATEDMTGTRTAADAVEAAREHLLLLQSPEGWWKGELQTNVTMDAEDLLLREFLGIRDE
DDTREAARWIRSQQAADGTWANFHDGPPELSTTVEAYVALRLAGDAPAADHMARAAAYIR
GEGGIPATRVFTRFWLAMFGRWPWDELPVVPPELMFLPRWFPLNVYDFACWARQTIVPLT
VVAAVRPVRPLPFELDELYPDYDVPRTAGRPRSGWDVVFQALDKALHLYERRPSKAVRRA
ALRRAADWIIARQERDGSWGGIQPPWVYSLLALHLLGYGLDHPVIRRGLDGLERFTVRDE
KGRRLEACQSPVWDTVLAMNALADAGLPTGHPALERAAGWVIREEVKGPGDWSVRRPELP
PGGWAFEFDNDCYPDVDDTAEVVIALNRVQHPLAEPAIERGVRWMAGMVSRDGGFGAFDA
DNTRALCRRLPFCDFGEVIDPPSADVTAHVVEAMAHRGMADSLLVKKAVVWLLKAQEPDG
SWFGRWGANHVYGTGSVVPALIAAGVRPEKPVIRDAVGWLERHQRDDGGWGEDLRSYRDR
SWVGHGASTASQTAWALIALLAAGERGESVERGVRWLVERQRPDGTWDEDHYTGTGFPGD
FYINYHLYRLVFPLSALGRYLKGS
>A0A4Q6I9N3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. F001|TrEMBL
MTATTDGSTGAQPPRAAAASETDSTTPEAAGGREAAVHAVRRATDFLLSRQDAEGWWKGD
LETNVTMDAEDLLLRQFLGIRDESTTRAAALFIRGEQREDGTWATFHGGPGELSTTIEAY
VALRLAGDAPDAPHMAKASEWIRAAGGVAASRVFTRIWLALFGWWKWEDLPELPPELIYF
PTWLPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPGDPNPVKPLAPAASW
DGAFQRLDKGLHALRKVVPRKLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSLIALHL
LGYDLQHPVMRAGLESLDRYAVRREDGARMIEACQSPVWDTCLATIALVDAGVPADHPQL
VKAADWMLGEQIVRPGDWSVRRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHDP
ERVEKAIGRGVRWNLGMQSKSGAWGAFDVDNTSLFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAAEGLAHDPRTRRGVRWLLAQQEPNGSWFGRWGVNYVYGTGSVVPALVAAGIPGSHP
AIRRAVTWLESVQNDDGGWGEDLRSYQDVERWSGRGASTASQTAWALMALLAAGEQDSKA
VERGVAWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRFVNGEPFAPA
KGS
>A0A846YWR6|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura latina|TrEMBL
MTTLETPETPERTGSRTAAEALDAARDHLLLLQSPQGWWKGELQTNVTMDAEDLLLREFL
GIRTDEDTYEAARWIRSQQAPDGTWANFHDGPPDLSTTVEAYVALRLAGDLPDAGHMIRA
AAYIRSEGGVPAARVFTRFWLAMFGRWSWDDLPVVPPEMVFLPRWFPLNVYDFACWARQT
IVPLAVVGALRPVRPLPFELDELVPDYDVPRKGGRGLPGWGAAFGALDKALHLYRRRPLK
GLRDAALRRAGEWIVARQERDGSWGGIQPPWVYSLLALHLLGYGLDHPVVQRGLDGLERF
TIRDEKGRRLEACQSPVWDTALAMNALADAGLPEGHPALERAAEWVIGEEVKGPGDWSVR
RPGLPPGGWSFEFDNDCYPDVDDTAEVVIALNRVRHPMAEPAIERGVRWMAGMASRDGGF
GAFDADNTRELCRRLPFCDFGEVIDPPSADVTAHVVEAMAHRGMADSLLVKRAVVWLLKA
QEPDGSWFGRWGANHVYGTGSVVPALIAAGVRPEKPVIRDAVGWLERHQRDDGGWGEDLR
SYRDRSWVGHGASTASQTAWALLALLAAGERGPAVERGVRWLAERQRPDGTWDEDHFTGT
GFPGDFYINYHLYRLVFPLAALGRYLKGS
>A0A6N7GUT4|squalene-hopene cyclase|EC 5.4.99.17|Hyphomicrobiales bacterium|TrEMBL
MLTSTDKGVSALEDRIGRAARALLDHQQPDGHWVFELEADATIPAEYVLMRHFRGEPVDA
ELERKIAVYLRRIQGAHGGWPLFHQGAFDMSASVKAYFALKMIGDPIDAEHMRRARDVIR
ARGGAARANVFTRTLLALYGQISWRSVPMMPAEVMLLPKWFPFHLDKISYWSRTVIVPLL
VLLALKPQAKNAKGVRIDELFLAPPDQARLTPRAPQQNKFWFAFFRMVDHVLRAVEPVLR
RLPTRVRSIKAAETFTIEHLNGEDGIGAIFPAMVNSILMFDVLGYPADHPLLTIARLSVE
KLLVVKDDEAYCQPCVSPVWDTGLACHAMLEVGGDAAVATVNKGLDWLKTKQILDVKGDW
AAARPDVRPGGWAFQYNNAHYPDVDDTAVVAMAMDRAQNLQGRTEHREAIDRAREWIFGM
QSKNGGWGAFDADNDHYYLNHIPFADHGALLDPPTEDVSARCVSMLAQLGDMPKNEPRVA
QAVDYLLKSQHPEGSWYGRWGMNYIYGTWSVLCALNTAGVDHQAPEVRKAVDWLVKIQNS
DGGWGEDGSSYKLDYKGYEPAPSTPAQTSWALLGLMAAGEIDNPAVARGIDYLSRTQGAD
GLWKEELFTAVGFPRIFYLRYHGYAKFFPVWAMARYRNLKRANSPSVAYGM
>A0A4R5AT80|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura darangshiensis|TrEMBL
MTTTEPAAQATAPKTAAGALDAARDHLLLLQSPEGWWKGELQTNVTMDAEDLLLREFLGI
RGDEDTFEAARWIRSQQAADGTWANFYDGPPDLSTTVEAYVALRLAGDPPDAGHMVRAAA
YVRGEGGVPATRVFTRFWLAMFGRWPWDGLPALPPELMFLPRWFPLNVYDFACWARQTIV
PLTVVAALRPVRPLPFGLDELYPDYDVPPRGKRGLSGWDVAFGALDKALHVYERRPVKGL
RRAALRRAAEWIIARQERDGSWGGIQPPWVYSILALHLLGHGLDHPVIQRGLDGLERFMI
RDGTGRRLEACQSPVWDTALAMNALADAGLPAGHPALERAAGWVIGEEVKGPGDWSVRRP
DLPPGGWAFEFDNDCYPDTDDTAEVVIALNRVLHPEAEPAIERGVRWMAGMASGDGGFGA
FDADNTRALCRRLPFCDFGEVIDPPSADVTAHVVEAMAHRGMADSQLVKRAVVWLLKAQE
PDGSWFGRWGANHVYGTGGVVPALIAAGVRPEKPVIRHAVGWLERHQRDDGGWGEDLRSY
RDRTWVGHGASTPSQTAWALLALLAAGERGPVVERGVRWLVEHQRPDGTWDEDHFTGTGF
PGDFYINYHLYRLVFPLSALGRYVKEIS
>A0A8G0UNQ3|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus pinatubonensis|TrEMBL
MSMNEAVLAAPRAAVATAAPALQAPIEALSPLDAGIGHAVDALLAQQNADGHWVYELEAD
ATIPAEYVLMVHYLGETPDLSLEARIARYLRRIQNADGGWPLFHEGRSDISASVKAYFAL
KMAGDDPQAAHMARAREVILAMGGAETSNVFTRTLLALYGVMPWQAVPMMPVEIMLLPQW
FPFHLSKVSYWARTVIVPLLVLNSLRPQARNPRKVGIDELFLGSRDAVRLPPRAPHQHKG
WHALFHGADVLLRTAEHVMPRGLRRRAIDAAKAFVRERLNGEDGLGAIFPAMANSVMMFD
VLGVPPDDPDRAIARRSIDKLLVVHGDEAYCQPCLSPVWDTALAAHALLEASEPRATAAV
TRALDWLRPLQVLDVRGDWTVRRPDVRPGGWAFQYANPHYPDVDDTAVVVAAMHRAARTD
HSGRADPNAEATARAIEWIVGMQSANGGWGAFEPENTHLYLNNIPFADHGALLDPPTADV
SARCLSMLCQTGATPDKSEPAARALQYLLAEQLPDGSWFGRWGTNYIYGTWSALCALNAA
GLGPDAPPLRRAAEWLVAIQNPDGGWGEDGDSYKLEYRGYETAPSVASQTAWALLALMAA
GQAAHPAVTRGIDYLLRTQQADGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWALARYRN
LERSGNRQVAWGL
>A0A7C4PUW8|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MSQSTTPDGKSGILREESKVFYGFEDALHRAIARSQSYLLSQQRDGCYWIGELIVDVTLV
ADMVAYHHWNGKVDPEWQRKAVNHIFSLQLPDGGWNIYYGGPSEVNATIKAYLALKLAGV
PITDPRMLKAREVAKNLGGVPRMNTFSKLYLALLGLYPWKYVPTIPCEVILLGKWFHVNF
HDMSNWTRAMLVPLAIINHFKPTRRPNPPVNLDELYPDGYKEHELALAPDPKFFSWRNFF
LWLDKLHKFAELWAQAGIHPFRRTALKRAEKWMLERFEGSDGLAAIFPAMLNSLIALKAL
GYPDDHPEVLRAERELKKLEHEEPNSVRIEPCLSPVWDTAITLIALVESGLSPDHPQVVA
ATRWLMDREIRFRGDWVHKNPAPVEPSGWVFEFNNKWNPDVDDTAMVLLALRLVPTDDPR
RRDEVFQRGYKWMLSFQCKDGGWAAFDKDCTKNVLTKVPFADHNAMLDPECADITARILE
VMGKTGCPLDNPQVQHALEYLKKEQQPDGSWFGRWGVNYIYGTWQTLRGLAALNYPMNEP
WLLRARDWLESIQHDDGGWGERCNTYDDPVFKGQGPSTASQTAWALMGLLAFGDPNRPSI
RRGVEYLIRTQNPDGSWTEHETTGTGFPQVFYLKYDMYRNNWPLLALAEYRKLLFLKEGP
NGKRHLQGLSADDLAAAPTRRP
>A0A522J9J1|squalene-hopene cyclase|EC 5.4.99.17|Sinobacteraceae bacterium|TrEMBL
MKTDDAMNTVKQSDEPRFAHDVRRRLARAGARAMEAVQSPRWGSGKHGDSSALDYQKSIL
PGVSRTFALTIPQLPQPLADVVANAYLLCRIADTIEDEPQLSAERKQQFQQRFGAVVGGR
APAEDFATELSAELSELTPETERELVRNTATVLRVTRRFGAAQRGALERCVDTMCHGMHS
FESRASAHGLAEVAELDRYCYYVAGVVGEMLTELFCAHSPVVARRRAELMRLAVSFGQAL
QMTNIIKDVWDDHARGICWYPRDVFERHGFDLDALSPTNHGPGFQAGVQELVAVAHSHLR
DALAYVLLIPAHERGIRLFCLWAIGMAAQTLDRINSHLDFASGAEVKISHRDVAMTTLLT
RAAVRSDRALTALFNRATARLPVPPTVAVPAPVARGPLPDAEPDMDPAARRWRKAGLDTA
IARSRDALLDLQKEDGHWCFELEADCTIPAEYILMMHFMDEIDVDLEQRIAKFLRSHQVL
DDHGGWPQYSRSAIDLSCTVKCYYALKLVGDDPDAPHMKQAREAVLALGGAAHTNVFTKI
MLAQFEQIPWRGVPFVPAEIMLLPKWFVFHLDKVSYWARTVMVPLFILMSRRRQAKNPRG
VDVRELFVTPPEEERHYLPAHDWLSRTFLVADRAGRFVEPYLAKLLQERAIKKAEEWFVP
RLNGEDGLGAIFPAMVNAYEALAELGYAKDHPLRATCLKSIQKLLVERPDGSVYCQPCVS
PVWDTGWSALALLNTSPTGKTDAVARKAIDRALKWLAPLQETELKGDWAIRAPDLTPGGW
AFQYRNAHYPDLDDTAMVAALLHVAGKGRYVERTDRAADWLAGMQSSNGAFGAFDVDNNF
LYLNKIPFADHGALCDPPTEDVSGRVLLALGILGRSQDRDAIRRCIAYLKQTQQPDGSWW
GRWGTNYIYGTWSVLAGLAFVGEDSGQPYIRRAISWLESRQNADGGWGETNDTYLDPTLA
GSMGGESTGYSTAWALLGLMAVGEVHSAAARRGIDWLVKNQGDDAFWSHDTYTAPGFPRV
FYLKYHGYTAYFPLWALARYRALTQRSGRSPRRPGAAAHSA
>A0A2X4WLN7|squalene-hopene cyclase|EC 5.4.99.17|Lederbergia lenta|TrEMBL
MEHQTKEAIEQIVQNLKLAQTANGSWDYPFDTGISTDAYMIILLRTLQINDEDFILQLTE
RIWSKQEANGAWKLFYDEGSGNLSTTVEAYYSLLYSGYVNKDNNRLQAAKSFIIENGGIE
KSFIFTKIMLSLTGQYSSPFHFPLPVEMILLPSSFPINFYDFSVFGRANLAPIMILSATK
YSKKTNRSPNLSDLFVSREDDFFKWKQTRETKRLFSTIEQGITSLLGLPQHIHSLAIHRA
KQYMLNRIEPDGTFYSYFSSTLLMIFALLSLGYSKKDQIIINAIKGLKTMKCKIDDHTHV
QYTTANVWNTSLISYVLKEADLSSTDLIVAKANQYLIRRQQYKYGDWLIHNPIGLPGGWG
FSNINTINPDVDDTTASLRAFSQIVPANLSFRYAWDKGIQWVLSMQNDDGGWPAFEKNVD
KKWLNLLPIEGGRFLLTDPSSADLTGRTLEFLGNYTNIPKIHPVIKRGVDWLLQNQENDG
SWYGRWGICYIYGTWAAITGLIASGITPKEKAIGKAKNWLHEIQNKDGGWGESCKSDLNE
SYIPLGASNLTQTAWALDSLIMISDKPTPEIQAGITYLLKSYDKKDWTTNYPVGQGMGGG
LYIHYHSYQFIFPLLALIHYRKKYE
>A0A7Z9RJ19|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirales bacterium|TrEMBL
MEQSIHYLLNQQDPRGFWVAELEADSTLTSEYIMLRRMLKKVDPEKERKKVSYLKAAQCA
DGGWPIYYGGPSNISASVKAYFALKLAGVSPDEPSMHNAREVILKMGGVVNTNVFTKIAL
ALFGQYDWQGIPSMPPEIILLPKQFPVSIHSVSYWSRVVLVPLLIIYASQPVNQVPKECG
IDELYVVPRNQIHVRRGPPFEADPRPVSWRNLFLLVDFALHLYSQRPLRPLRGLAIKKAT
DWMLERMQGNGGLGAIYPAMANSVLALHALGYGTDHPLVSKALSEIEELEVESEDMLHLQ
PCFSPIWDTCLLTNTLVESGLSRTHPGLLKAGHWMLSQQTKKVGDWKVSAPQAQPGGWCF
QFENEHYPDCDDTAVVLMALAKLDFPNKTEQRQAIIRGLQWLLPMQGRDGGWASYDKDNN
ATMFNEHPFADHKSLIDGSTADIVGRVLEMLGVLGFDQTFPPARKAIAYLKKDQEANGSW
YGRWGVNYIYGTWSVLAGLRSIGEDLSQPYIRKAVHWLKETQHDDGGWGESCQSYADQSL
AGVGESTASQTAWALIGLLCAGEVQSDNVTRGIESLIRSQKPDGSWEERFHTGTGFPRVF
YLRYHWYGQYFPLWAFSMYHSLKTRSRLRADDIAKHNRNQGWYVQHSKKI
>A0A6B3BJ77|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID9727|TrEMBL
MTATTDGSTGAVDPRAASASRKTTESTIAADGVQAAARRAAERSVEHLLGRQDEQGWWKG
DLATNVTMDAEDLLLRQFLGIQDPATVRAAAGFIRGEQLGDGTWATFHGGPADLSTTIEA
YVALRLAGDRPEDPHMARAAGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMF
FPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPEHPNPPKRPAPARS
WDGFFQRLDKALHVYHRFAPRRLRRVAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVMRAGLESLDRFAVWREDGTRMIEACQSPVWDTCLATIALVDAGVAPDHPA
LVKAADWMLAEEIVRPGDWAVRRPGLEPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPD
QARVDAAIERGVRWNVGMRSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHV
VEMLAVEGRAAHPVTRRGVEWLLSEQDAGGGWFGRWGVNYVYGTGSVVPALTAAGLPPSH
PAIRRAVEWLESVQNDDGGWGEDLRSYTEEKWIGQGASTASQTAWALLALLAAGRRDTVA
VTRGIAWLTETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFAGR
TPTHEGA
>A0A372ITQ2|squalene-hopene cyclase|EC 5.4.99.17|Acidipila sp. 4G-K13|TrEMBL
MSTPTGTAQSGSAEDPVVKRAGEASPAADGRQNGSVKFGRIDASLEDVERATVRSRDHIF
SMQHGEGYWCGELEADAMLEADYIFAHVLLGTGDAGKMRRALAEILRYQQEDGSWSIYPG
GPGNISLSVKCYFACKLMGMEPENPILVKARAWILAHGGVTACNTFTKIYLCSLGQYEYD
AVPAVPPEIVLFPKWFYFNIYEISSWSRAILVPLSITYAKKPFKKIPAEQGIDELFVGGR
ENANLHLRMDRQKKIGWRNFFLLCDRVVHWLERVHIRPLRAIALKKAEKWMLERFEMTDG
LGAIYPAMLNSIIAMRCLGYSLDDPQVIRAMDEFEKLGIDEPNGTADYPEPTFRMQPCMS
PVWDTAQAVYALGEAGVSRNDARLLQATDWMLSKEVRHKGDWAVKNRKAEPGGWYFEFNN
EFYPDVDDTAQVLLALNKIDNPRERYQYDVCQRAIEWIFSMQCRNGGWASFDKDNTKMIF
EHIPFADHNAMLDPPTVDITGRILEALATYGYTRRDKRVEKAIKFIYVEQEPDGSWFGRW
GVNYLYGTFLVLRGLEAIGVWNHEPQVQQAAEWIRSVQNADGGWGESCGSYDDPVTRGVG
ISTPSQTAWAILGLLAAGDTRSDSVAKGIKWLLAHQQPDGSWDESLGHGRTRQAIYTGTG
FPRVFYLAYHQYRDYFPLLALTNYKRAMEREH
>S7UB52|squalene-hopene cyclase|EC 5.4.99.17|Geobacillus sp. WSUCF1|TrEMBL
MQKAKARILEMGGLERVHLFTKVMLALTGQHPWPRRFPLPLEFFLLPPSFPLNMYDLSVY
GRANMIPLLVAAERRYSRRTAKSPDLSDLVVSRNDWRLPESRSLWSYIKRSLIGLPDQLH
HAAEQRAVRYMLDHIEPDGTLYSYFSSTFLLIFALLALGYPKDDPYIQRAIRGLRSLRTE
IDGHTHMQYTTASVWNTALASYALQEAGVPLTDRTIEKANRYLLSRQHIRYGDWAVHNPY
GIPGGWGFSDVNTMNPDVDDTTAALRAIRRAAAKETAFRHAWDRANQWLFSMQNDDGGFA
AFEKNVGKRFWRYLPIEGAEFLLMDPSTADLTGRTLEYFGTFARLTKDHPAVARAVDWLL
DHQEADGSWYGRWGICYVYGTWAAVTGLSAVGVPIDHPAMQKAVHWLLSIQNADGGWGES
CKSDGAKTYVPLGASTPVHTAWALDALIAAAERPTAEMKAGVRALIRLLRHPDWTASYPA
GQGMAGAFYIHYHSYRYIFPLLALAHYEQKFGPFVD
>A0A286RF18|squalene-hopene cyclase|EC 5.4.99.17|Thermogutta terrifontis|TrEMBL
MDEPWQGGDSLRPRGENRLRLAYTTRPRSTLESQLRRSVSRGRWCLLNRQYPDGHWRAEL
EGDSILQSETILILAFFHRESSELVSLLASRLLETQTAEGGWSLYPGGPLDISATVKAYF
ALKIAGFDLHEEPIRRARDAILARGGAQSVNSFTRFYLAFLGQIPYSACPAVPPELVLLP
RWFPINLYSLSAWSRTMVVPLSIIWALKPVRTLPPEKGIRELFLTRPENWPLTRGSRSAR
LEWFWSRFFSAVDRLYKLCDRHRLVPLRQKALRAAEAWILQHLEGSHGLGAIYPAMVWSL
IALKALGYDEESPLMRTGWRHVEELIISDENNHTARVQPCLSPVWDTTLAVRCLRESGLG
IDHPALRRGVHWLLGRQILKPGDWALHTQAQPGGWCFQYANDHYPDCDDTAAVLLALAAL
FQTESPADGLFPPQWELVNPPDKCEGRLNHPGDDRLSHGRLERLSGEEALADATRAIDRG
LKWLLAMQNDDGGWAAFDRNNCCQLLTQVPFADHNAMIDPSTPDVTGRVLEALGNLGYRV
GHPAVDRAVRYLRAVQEPDGSWLGRWGVSYIYGTWLALAGLDAVGIPEHDPSVLAGATWL
IGHQLPDGGWGETPETYDNPAKRGAGPSTPSQTAWAILGLLAAGKSRHPAVLRGVRYLLD
RQQSDGTWAEEAFTGTGFPRVFYLRYHHYPLYFPLMALARFATVNAPYLEELDLPELRVL
VPKQDHLSSESRSA
>A0A6G2TC49|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8366|TrEMBL
MTATTDGSTGATLPSRAAAASDTTLTTPEAAGVPEAAARAARRATDFLLARQDAEGWWKG
DLETNVTMDAEDLLLRQFLGIQEERTTQAAAKFIRGEQREDGTWATFWGGPGELSTTIEA
YVALRLAGDAPDDPHMARAAAWIRERGGIASARVFTRIWLALFGWWKWEDLPEMPPELIW
FPGWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPANPNPPKALAPANT
WDGAFQRLDRALQQLRKVVPRRLRRAAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVLREGLASLDRFAVWREDGARMIEACQSPVWDTCLAAIALVDAGLPADHPQ
LVKAADWLLGEEIVRPGDWAVKRPQLPPGGWAFEFHNDNYPDIDDTAEVSLALRRIRHHD
PERTDRAIGRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAAEGLAHDPRTRRGIAWLLAEQEQNGAWFGRWGVNYIYGTGSVVPALTAAGMPVAH
PAIRRAVTWLESVQNDDGGWGEDLRSYKHVREWAGRGASTPSQTAWALMALLAAGEKDSP
AVERGVQWLAATQREDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFER
QLLARTPRPRTAAAKPAGSPLAEAKGS
>A0A534S5D0|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MTVEKRFSSGLTPGDDEFLYGVERAITQAQDYLLREQKPEGYWYYPLEANATMDAEYIFF
NHFMGRVDEKKHQHLCEHLLAVQADDGAWPLFYGGPGHLGNTIEAYFALKLTGYSADHPA
LVKARQFILGQGGLSRAQVFTRIFLAYFGQFPWRGVPALPVEMVLLPPWFPLNIYEMSSW
ARGTVVPLTITLAQRPCVPIPDACGVAELWKDPPERSDLGFPRSPQLVSWENFFIELDKV
LKLLGKSPVKPLRKRALRKAERWVLAHQDANGGWGGIQPAMLNSVMALHSLGYAPDHPAV
AKGIQAMEDFLMESGGYLFFQPCVSPVWDTVWVIKALIDSDFPTDHPAITKAADWILDRQ
ILKTGDWQIKNPELEPGGWAFEFANDWYPDVDDSAVILFTLKRVTGLDERKKDHGIARGL
NWILGMQSRNGGWGAFDTDNTLDLWNQMPFGDMKAMIDPPTADVTGRLLEMMGAFG
>A0A534U773|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
LLVTQHARGYWHAPLEANVTMEAEYIFFNRLLGRTKPDLDRRMAERLVALQQAEGSWPIY
AGGPGNLSTTIEAYFALRLAGHAPSEPALVRARDFILAEGGLARAGVFTRIWLAYFGQFP
WIGVPAMPVELVLLPPWFPINIYAMSSWARGTVVPLTLLMAHRPYAHVGAEAAVPELWLR
PPTPADLAFARSREFATVRNLFLAVDRALSVVGRSPWKPLRRRAVARAIEWILRHQDKNG
QWGGIQPAMLNSVLALHAVGFAPDHPAMVSGVHGVDDFLVECEGTLMYQPCVSPNWDTAL
AARALLDSGMEPTHPALERAGEWLVANQIFRPGDWAVQRPSLEPGGWAFEFANDWYPDVD
DSAVILTVLRELPLAATPDGKRAIAYGLNWTIGMQSRNGGYGAFDADNTAAFLNRIPFAD
MEAMIDPPTADLTGRLLQLMGGEGYGLDFGRARRAVEFLRRTQRPDGSWWGRWGVNFIYG
TWCALTGLAAIGEDLRAPYIRRAVEWLIARQNADGGWGETVASYDDETLAGRGESTPSQT
AWALIGILAADGPASAAVERGIDYLVRTQGADGTWTERPFTGTGFPRHFYLRYHLYRHYF
PLMALGHYRAGLAGRSGEEG
>A0A4R9M895|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. USMB20|TrEMBL
MIRRMNKPAPSPWSALDTAIARGRDALMRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDARQEQMARYLRAIQRLDTHGGWDLYVDGDPDVSCSVKAYFALKAAGDSEQAPHMVRA
RDAILKLGGAARANVFTRILLATFGQVPWRAAPFMPVEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNIAIPELFVTPPDQERQYFPPARGMRRAFLALDRVVRHVEPL
LPKRLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMDVLGYPDDHPLRRDCENAL
EKLLVTRPDGSVYCQPCLSPVWDTAWSTMALEQARGVAAPDAGEPAGSLNELDARIARAY
DWLAERQVNDLRGDWIENAPADTQPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRTHRNA
DGSHPYAARVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRAADRASLARAIDYVKRTQQPDGSWWGRWGTNYIYGTWSVLAGLALAGED
PAQPYIARALAWLRARQHADGGWGETNDSYIDPALAGTNAGESTSNFTAWALLAQMAFGD
CESDSVKRGIAYLQSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GAALAGTSSSSGAGVSASRTTDTALA
>A0A1A0DDA8|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter pasteurianus|TrEMBL
MAADGSALSESRLSSEALDRAVLSAHTALSQAQQDDGHWVYELEADATIPAEYILLEHFM
DRIDDALEQKIAIYLRRIQSEEHGGWPLYHNGKFDLSATVKAYFALKAVGDDINAPHMQR
AREAILDHGGAERSNVFTRSQLALFGEVPWRATPVMPVELMLLPAKAFFSVWNMSYWSRT
VIAPLLVLAALRPVAANPRQVHVRELFVTPPEKVQDWIRGPYRSAWGYVFKGLDSVLRPV
VPFIPEKTHKKAIQAALDFIEPRLNGKDGLGAIYPAMANVVMMYRAMGVPDEDPRAKTAW
EAVQALIVEKDDEAYCQPCVSPIWDTGLSGHAMIEAASGPNGIAPEKTVAELKKASAWLR
SKQILNVKGDWAVRNPNLAPGGWAFQYGNDYYPDVDDTAVVGMLLHREGDPANAEAIERA
RTWIVGMQSTDGGWGAFDINNNKDVLNHIPFADHGALLDPPTADVTARCISFLAQLRNPE
DEPVIQRGLEYLRKEQEKDGSWFGRWGTNYIYGTWSALCALNAAGVSHDDPAVVKAVEWL
RSVQRADGGWGEGCESYEGGPHGTYGESLPSQTAWAVLGLMAAGRRDDPAVTRGIAWLAD
QQDANGEWHEDPYNAVGFPKVFYLRYHGYKQFFPLMALARYRNLESSNTRRVSFGF
>A0A3N7RLB2|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia ubonensis|TrEMBL
MKPNHAFSPSALDAAILRGRDALSGLQQPDGSWCFELESDATITAEYILMMHFMDKIDEV
RQAQMARYLRAIQRVETHGAWDLYVDGAPDISCSVKAYFALKAAGDSEHAPHMIRAREAI
VKLGGAARSNVFTRILLATFGQVPWRAAPFMPVEFVLFPKWVPISMYKVAYWARTTMVPL
LVLCSLRARARNPRNVSIAELFVTPPDEERHYFPPAKGMRRLFLALDRTVRHLEPLLPRR
LRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMEVLGYPEDHPLRRDCEDALEKLL
VTRADGSVYCQPCLSPVWDTAWSTMALEQARGVTPAAPGAQTSDCDLDARIARAYDWLAT
RQVNDLEGDWRENARPGTQPGGWAFQYANPYYPDIDDSAVVTAMLDRRGRAQARASGENP
YAERVTRALDWMRGLQSRNGGFGAFDADCDRLYLNAIPFADHGALLDPPTEDVSGRVLLC
FGVTKRPADRAAAARAIEYVKRTQQPDGSWWGRWGTNYVYGTWSVLAGLALSGEDKSQPY
IARALDWLRAHQHADGGWGETNDSYADPQLRATNYGESTSNCTAWALLAQMAFGDWQSDS
VRRGIAYLLSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLAGAQAA
PSAPGPGAAATISDPAVA
>A0A5C4JHS9|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura soli|TrEMBL
MTAVEKTTGTRTAADAVEAASEHLLLLQSPEGWWKGELQTNVTMDAEDLLLREFLGIRDD
GDTREAARWIRSQQAADGTWANFHDGPPELSTTVEAYVALRLAGDLPGADHMARAAAYIR
GQGGIPATRVFTRFWLAMFGRWPWDELPVVPPELMFLPRWFPLNVYDFACWARQTIVPLT
VVAAVRPVRPLPFTLDELYPDYDVPRQAKRRTGWDAAFQALDKALHLYERRPAKAVRRAA
LRRAADWIIARQERDGSWGGIQPPWVYSLLALHLLGYGLDHPVIQRGLDGLERFTIRDDK
GRRLEACQSPVWDTVLAMNALADAGLPTGHHALERAAEWVVREEVRGPGDWSVRRPELPP
GGWAFEFDNDCYPDVDDTAEVVIALNRVQHPPAEPAIERGVRWMAGMVSRDGGFGAFDAD
NTRTLCRRLPFCDFGEVIDPPSADVTAHVVEAMAHRGMADSLLVKRAVVWLLKAQEPDGS
WFGRWGANHVYGTGSVVPALIAAGVRPEKPVIRDAVGWLERHQRDDGGWGEDLRSYRDRS
WVGHGASTASQTAWALLALLAAGERGESVERGVRWLVERQRPDGTWDEDHFTGTGFPGDF
YINYHLYRLVFPLSALGRYLKGS
>T2AYK9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLAMHAVLEANSVPDKIFMEKAANWLVKRQILDVIGDWGANVHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDCYSKAIARGAEWIIGMQSGNGGWGAFDVNNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGLDNQAVARAIGYLKRGQEVNGSWYGRWG
>T2AZL6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIIMEKAANWLVERQILDVIGDWGANAYGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWYGSWG
>T2AZY3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWYGRWG
>T2AZR0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQFLDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGRWG
>A0A7C2KH80|squalene-hopene cyclase|EC 5.4.99.17|Spirochaetes bacterium|TrEMBL
MFNTSLPKRPFQKEKSPAIQVEKVDESITRASDFLLSLRENREYWNGRLDSNAGLNAQYL
LLNYILSLKPDPLTSQKVIHYILSQQQTDGSWSIYYGGPGHPSYSILCYFALKLYGFSSE
DPVMIRSRDFILSAGGLLKANVETKFFLALLDQISWDSLPPIPVQIMLAPNRFLFSIYNI
AYWCRISLIPMSVIYTKKIVISPPESAYIPELYPSPPKTFKSNESPLPFLSLRNLLLQMT
KVFKYLEKLSPNILDEAAITKAKSWILSHQDDSGDWGGVYPGTQYSLIALHILGYSRESP
EIQRGLKALDGLLVKTEKDIMVSASLSPVWDTAWAVLSLQSAGCHQENPAIEKACQWLYN
HQILVKGDWSVKTPKASPGGWCFQFHNDLYPDTDDTALVLMALLPTLARDENHEPFKRGI
DWLLSMQNDDGGWGAFERKVDKEIINALPLNDIGNFLDPSTADVTGRVLELLGKTGYTQK
DSVVQRAIRFLKYRQEDFGGWYGRWGVNYIYGTWSVLQGLGSIGESMDASYIDRSIRWLK
SCQNLDGGWGESCLSYEDKSYAGVGRTTASQTAWAILALIAAGHHPSVEVEKGIDYLVKT
QNIKGGWDELEYTGTGFEGAFYLKYQYYPYIFPLLALGQYKNR
>T2AYJ7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLVMHALLEANLALDKAIMQKAADWLVERQILDVIGDWGANARGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRVDPNRYSEAIERGAEWIIGMQSGNGGWGAFDKDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMLAQLGYGYEIEAVSRVVGYLKREQEHDGSWYGRWG
>T2B0J5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTALVSQALIETEYKQHVSTEIEAALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTVGVTGRAITLLSLADKKIYAKNIKDGVDYIKSEQEEDGSWFGSW
G
>T2B004|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAIATIALRDAGVPAEHPSLKRTVDWLLDKEVRRSGDWTVRNSETEPAGWYFELN
NEFYPDVDDTCMVLMALARCLPNQPEWDADFLVDDWSPHEADKDVTAVLAARNADSVLAA
VQVDGLRPMLGAMHRGARWILAMQSKDGGWGAFDRDNVRKLFTQVPSADHNAMIDPSTAD
LTARMLEMFSYLNVPADHPVVRRAIDFVWKDQDPEHCWFGR
>T2B0B7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGLAARAILETHGGDTHLLNKSCDWLSKLQIKEHTGDWGWRRKGLRPGGWAFQYN
NKFYPDVDDTAVVGMALHRQDPEKYADTISRAEEWIIGMQSSNGGWAAFDADNEYYILEN
LPFADHRALLDPPTADVTARCISFLTQIGTSNNHPISRGLEFLKRNQEEDGSWYGRWG
>T2AYH7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDDPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPVQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGPWYGRW
G
>T2AYP8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLSGISLLESGLTLKDIAIQKACTWLEKKQILGMKGDWFANNKNLLPGGWTFQY
ENDFYPDVDDTAVVAMFLDRAGYQNKKRLERACNWIVGMQSKNGGWGSFDKDNTCHYLNN
IPFADHGALLDPPTADVSARCVSMLSQINKKNYKNVIQKGVEFLKNEQEEDGPWFGRWG
>T2AZD1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLAAHAVLETHGGNTHLLNKSCDWLSKLQIKEHTGDWGWRRKGLRPGGWAFQYN
NKFYPDVDDTAVVGMALHRQDPEKYADTISRAEEWIIGMQSSNGGWAAFDADNEYYILEN
LPFADHRALLDLPTADVTARCISFLTQIGTSNNHPISRGLEFLKRNQEEDGSWYGRWG
>T2B098|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDDPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAIALLSLADKKTYEKNINDGVNYIKSEQEEDGSW
>T2B044|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLATHAMLEANLSSGPRILENDSTSKACKWLEKLQIKDCAGDWAVWRPNLRPGG
WAFQYHNDYYPDIDDTAVVAMALHRTGNKIYEPALLRAAEWIIGMQSKNGGWAAFDADNE
YHLLENMPFADHGALLDPPSVDVSARCISFLTQLGYDQTNGTIKRGIEYLKKNQEEDGSW
>T2AZK8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTCLSLTALSEGGAPNDHPAVRQAVDWLFDNQIFVNGDWSKNAKGLESGGWAFQYE
NDKYPDVDDTGMVLMALLRAGAHEKDAKKKRLNQALNWVLGMQNPDGPWGAFDIGNNCGY
LNNIPFADHGALVDPGTADLTARCIELLSMVGYGSESPVVTRALRFIREDQEEDGSWYGR
WG
>T2AZ05|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIEAALNRLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAVALLSLADKKIYEKNIKDGINYIKSEQEEDGSWYGSW
G
>T2B035|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAALALQEADPKGTRQSREKAYNWLKTKQSDKQPGDWQIRQPHLEGGGWAFQF
ENPHYPDVDDTAVVAFAMANADLPNLNESINRATRWTAGMQSKNGGFGAFDCDNTGYYLN
HIPFADHGALLDPPTADVSARCAMLLGHQIKNHPEYQTTLDDTIAYLRSEQETDGSWYGS
WG
>A0A4S3HKB5|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cepacia|TrEMBL
MIRRMTRSTPSPWSALDTAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDLRQERMARYLRANQRLDTHGGWALYVDGDPDVSCSVKAYFALKAAGDSEHAPHMVRA
RDAILKLGGAARSNVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNVSIRELFVTPPDEERRYFPPARGMRKLFLALDRTVRHVEPL
MPKGLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMQVLGYPDDHPLRRDCENAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVSVPEDGEPDDARRALDARIARAY
DWLAERQVNDLRGDWIENAPADVQPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRTHCNA
DGTNPYAPRVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRADERASLARCIEYVKRTQQPDGSWWGRWGTNYIYGTWSVLAGLALAGED
KSQPYIARAIEWLRSRQHADGGWGETNDSYIDPKLGGTNGGESTSNFTAWALLAQMAFGD
CESDSVKRGIAYLQSVQQEDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GAAAAAPATVDAADTAVA
>A0A6H0CVX1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. DSM 40868|TrEMBL
MTATTDGSTGAILPSRAAAASDSTLTIPETAGVQEAAARAVQRATDFLLARQDTEGWWKG
DLETNVTMDAEDLLLRQFLGILDENTTRAAAKFIRGEQREDGTWATFYGGPGDLSATVEA
YVALRLAGDAPGAPHMAKASAWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELIF
FPTWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPANPNPPQPLAPVAS
WDGVFQRLDKVVRGYRKVAVRRLRKAAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLKHPVLREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALVDAGLPADHPQ
LVKAADWMLGEEIARPGDWAVRRPELPPGGWAFEFHNDNYPDIDDTAEVALALRRVRHHD
PEHVDRAIGRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAAEGLADDPRTRRGIDWLLAEQEPNGSWFGRWGVNYIYGTGSVVPALTAAGLPTSH
PAIRRAVTWLESVQNDDGGWGEDLRSYKDAKEWSGRGASTASQTAWALMALLAAGEKGSA
AVERGVRWLAGTQREDGGWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLYGDPFER
KLLTAPAGKVSARAEGD
>A0A5S4YH15|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium hipponense|TrEMBL
MDSVNATAREVLESSIASATQGVLGFQQSDGHWVFELEADCTIPAEYVLLRHYLAEPVDT
VLEAKIGNYLRRVQGAHGGWPLVHDGEFDMSASVKSYFALKMIGDSIDAPHMVRAREAIH
ARGGAIQSNVFTRFMLAMFGVVTWRAVPVLPIEIVLLPFWSPFHINKISYWARTTMVPLM
VIAALKPRAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFMLFRALDGILRVVEPMFP
KSLRKRAIDAALAFIEERLNGEDGMGAIYPPMANIVMMYDALGKDENYPPRAVTRRGIDK
LLVIREEEAYCQPCVSPVWDTTLTAHALLEAGNAEAVPAAKRGLDWLIPKQELEVKGDWA
VKRPDVRPGGWAFQYNNAYYPDLDDTAVVVMSMDRMRREHGATGYDAAIDRGREWIEGMQ
SDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETAQTSKHVAD
GVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVRHDDPMIRKATGWLASIQNAD
GGWGENAVSYRLDYKGWEAAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIATQNEKG
LWDEQRYTATGFPRVFYLRYHGYAKFFPLWALARYRNLRDTNSRVVGVGM
>A0A7K2UQI7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID7813|TrEMBL
MTATTDGSTGASLRPLAASASDTDITIPAAAAGVPEAAARATRRATDFLLAKQDAEGWWK
GDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDSPEAPHMARAAEWIRSRGGIASARVFTRIWLALFGWWKWDDLPELPPELI
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPARPNPPRPLAPVA
SWDGAFQRIDKALHAYRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPEDHP
QLVKASDWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHH
DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAVEGLAHDPRTRRGIQWLLDAQETDGSWFGRWGVNYVYGTGSVIPALTAAGLPTS
HPAIRRAVRWLESVQNEDGGWGEDLRSYRYVREWSGRGASTASQTGWALMALLAAGERDS
KAVERGVAWLAATQREDGSWDEPYFTGTGFPWDFSINYNLYRQVFPLTALGRYVHGEPFA
KKPRAADAPAEAAPAEVKGS
>A0A7C5X090|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Acetothermia bacterium|TrEMBL
MPGVKEKKDPREYLIVDRPAPSTHGRSGVEDLDEAISRAVDWLLSRQSPEGWWWAELESN
VTITAEHLFLTHILGIGSQELWEKIARYILSAQRPEGFWANWYGGPGDLSTSVEAYVALK
MAGVDPNSPPMKKAREWILSQGGVEKARVFTKIWLSMLGEWPWDATPMLPPELVLLPERF
PVNLYSFSSWARGTILPLAILRVLKPVCPIPPHARIDELFARGRANADLSLPRKKSLWGR
FFYGVDKALRLYERRPLRSLRRLALKRAEEWIVERQEADGCWGGIQPPWVYSLLALFALG
YSLESPVLAKGIAGFERYSIEDECGFRLQSCISPVWDTGLALLALQDAGLPPDHPALIRA
GSWLLGEQIFVGGDWQVKCSARPGGWAFEFDNDVYPDTDDTAVVLMALLGVSLPERAKDF
ALKRGLEWLLGMQSKNGGWGAFDRNNTKTFLREIPFADFGELLDPPSEDVTAHIVELLGR
LGYRPGFEPLDRALRYLFREQKAEGPWYGRWGVNYLYGTGAVLPALRAVGFPMNDPRVRR
AVEWVLSRQNPDGGWGEDVLSYHKKELWGRGPSTASQTAWALLALLAAGEAKNPAVRRGV
EYLIRTQNDEGTWNEPYYTGTGFPTDFMIRYHLYRHVFPLMALGRYRRAVMSDT
>A0A3N8HZM6|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp8992|TrEMBL
MNDLTEMATLSAGAVPAGVDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGNYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPIAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKALDKLLVVHEDEAYCQPCLSPVWDTSLAAHALLETGDARAEEAVLRGLEWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLKQSDTYRDSMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTSDVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGIDYLV
AHQNDEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRGNTTRVTVGM
>A0A538ECJ8|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MTGPVAAAVAYDEAEVRAREALGRASDHLLSLQDAAGWWKGELETNVTMDAEDLLLREFL
GIRDEGRTSRAAEWIRAHQRADGTWGNYFGAPGDLSTTVESYAALRLAGDSPEAEHMRRA
AEWIRAQGGLERARVFTHIWLALFGLWDWDRVPALPAELIFLPSWVPLNVYDFACWARQT
IVALMVVMAYRPVRPLPFGLDELRSWDEEPPRVRPCTPTGRLLARLDRLARTYDRRPLRP
LRRLALAAAERWIVRRQESDGSWGGIQPPWVYSLMALDLRGYPLDHPVMRRGLEGLDAFT
IDDPDGFQRLEACQSPVWDTALAIIALTDAGLDPDHPALLAAGDWLVAQEVRAKGDWAVR
RPHLPPGGWAFEFANVNYPDVDDTTEVVLALRRLRHPHPWRIDEPVARGVRWVLGMQSAG
GGFGAFDADNTRELCRQLPFCDFGEVIDDPSADVTAHAIEMLAGEGLSDSPPAREAVEWL
LGQQEADGSWYGRWGVNHVYGTGAAVPALVDAGIPREHPSILRAVAWLHQRQNPDGGWGE
DCRSYEDESWIGRGESTASQTAWALLALHAAGDESPALERGVAWLVDTQRPDGTWDEPQH
TGTGFPGDFYINYHLYRLIFPIAALGRILGG
>A0A537ZD66|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MTATGHLAQERNVTPRDAHTALADGRDALLALQHADGWWKGELQTNVTMDAEDLLLRRFL
GIDDRDLTRRAANWIRSQQRADGTWATFFDGPADPSTTVEAYVALRLAGDPAEAAHLRRA
AEFIRDEGGLEQTRVFTRLWMALFGEWSWNDLPALPPELVLLPPWSPVSIYDFACWARQT
VVALTVVAAHRPARVLGFPIDELRTGKFRRGRAGWGSRTERFELLDRVLHAYERHQVSWL
RRAALARAERWIVHRQEADGSWGGIQPPWVYSLMALALQGYPLDHPVMRAGLEGIEGFAI
EATDSRWLEACQSPVWDTALAVIALSDAGLGADDPALVRAGNWLLDEEITIAGDWAVRRP
DVPPGGWAFEFANDNYPDIDDTAEVVLALRRVTLPDAARAEATIARAVHWTLGMRSGDGG
WGAFDADNDAQWCRDLPFCDFGEVIDPPSADVTAHMLEMLALEQGVRREVLDGAIAWLTR
SQEPGGSWFGRWGVNHIYGTGAVVPALVAAGIAPSDPHVRAAVRWLEAHQNADGGWGEDL
RSYRYPEWIGRGESTASQTAWALLALHAAGERNGDATRRGVAFLVATQRPDGTWDEPYFT
GTGFPWDFSINYHLYRVVFPVMALGRYVTSDQAEQAS
>A0A3R9BLL9|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cenocepacia|TrEMBL
MIRRMNKSAPSSWSALDAAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDR
IDDVRQEKMARYLRANQRLDTHGAWDLYVDGAPDVSCSVKAYFALKAAGDSEHAPHMIRA
RDAILKLGGAARSNVFTRILLATFGQVPWRAAPFMPVEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNVSIRELFVTPPEQERHYFPPARGMRRLFLALDRTIRPIEPL
LPKRLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMQVLGYPDDHPLRRDCENAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVAAPETGDTASGALRDLDGRIARA
YDWLATRQVNDLCGDWIENAPADVEPGGWAFQYANPYYPDIDDTALVTAMLDRRGRTHRA
ADGTHPYASRVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVS
GRVLLCFGVTKRAADRASLARAIDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALAGE
DKSQPYITRALDWLRARQHADGGWGETNDSYLDPKLAGTNGGESTSNCTAWALLAQMAFG
DCESDSVKRGIAYLQSVQQEDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRL
AGAKDAGATRSCASGASAAPATDDALA
>A0A5N9E9W1|squalene-hopene cyclase|EC 5.4.99.17|SAR202 cluster bacterium|TrEMBL
MVRRARLCGRKEPKSGDATTVAQLKHSDVNQAADEAVQRSQDYFRRTQYPEGYWWGELES
NPTMEAEYLMLCHFTGRHDQERWRKICNYILSKQRSDGSWSQYYEAPGDVSTSVECYFAL
KLAGHSPDTEPLRKAREFILSKGGIPKVRVFTKIWLALFGQWDWKGTPNMPPEMIFLPSW
APFNIYEFASWARATVVPMLIILTRQPYCAVPESADIGELYPGGREGTDYHLPKPTGGFG
WSKALYWADKLVGLYQRLPVHPFRGRAERKIIQWVLDHQEADGSWAGIQPPWVYSLITLH
TLGYGPDHEAVKKGFQGFERFALEDEDKCNVQACISPVWDTCIAQLALLESGIDPEDPMV
QSSARWLMDKQIYAAADWQVRAKDTRPGGWSFEFDNLIYPDIDDASIVVMALDQVRLPEA
EEPRRADSIQRGVEWMAGMQSKNGGWAAFDKDNNKKYLTKIPFSDFGETLDPPSVDVTAH
LLEMYGRLGYTKEDRAVDRGFAYVISEQEEDGSWFGRWGVNYVYGIGAVLPALEAIGEDM
SQAYIRLAVDWTVAHQNQDGGWGESCGSYVDPNLHGVGPSTASQTAWALLGLVAAGEHES
EAAQRGLVYLAETQLEDGTWDEPYFTGTGFPGYGVGERLKAMPDIGETSYQGLDMPAGFM
INYHLYR
>A0A843RHE1|squalene-hopene cyclase|EC 5.4.99.17|Kiloniellaceae bacterium|TrEMBL
MTSSTVARDRDVPPVPVAAPLPDLDAVDALVGEMRSALKAEQRPDGHWLFELEADATIPA
EYIFLQHFLGQVDTPRFREIEPKIANHLRAIQGRHGGWPLFYDGDLDISASVKAYFALKL
AGDDPEAPHMQRAREAILDAGGAAQSNVFTRIALALFGQVPWRAVPEMPVEIMLLPRWFP
FHLSKMSYWSRTVIAPLLVVMDRKPQAANPRGISVRELFRGDPAREIYNMNASGSPLGAI
FAGIDRVLRFSDPLRPRAKRQKAINAAMDFVKERLNGEDGLGGIFPAMAIAAMAFHVLGY
DWEDPDYRLTREAIDRLLFARDEHTVTCQPCLSPIWDTCLAAHAMLEADVPVDSDSISRA
FDWLLGREITEVRGDWAWRRAEAPVGGWPFQYNNAHYPDVDDTAVVVLAMNRAGSEACKP
AIERATKWVIAMQSRNGGWGAFDADNAFQYLNHIPFADHGALLDPPTADVSARCLSMLAQ
LGYGRDHTVVRRGLDYLRREQEADGSWYGRWGVNYVYGTWSALAAFNACGEDMVAPHIRK
AVAWLQRRQLPDGGWGEDCATYWSERRAETKSSTASQTAWALLGLMAAGEVESDAVRRGI
AFLQQQPRQGARWAEDYWTGTGFPRVFYLKYHGYSAYFPLWALARYRNLMQSNERRVSYG
M
>A0A7X6RGU5|squalene-hopene cyclase|EC 5.4.99.17|Nocardia veterana|TrEMBL
MTVTETGKATERRTAVESPCGADDLTSVRTATDAAVRLLRASQHEQGWWKGELATNVTMD
AEDLLLREFLGISDPEVTASAARWIRSQQRADGTWATFHGGPGDLSTTAEAWVALRLAGD
DPSAPHMRAAAEFVRAEGGIEASRVFTRIWLALFGLWSWDDLPNLPPELVLFPSWFPLNI
YDWGCWARQTVVPLTVVATLRPCRPLPFGIDELRTGAPAAPRAPITTLAGVFQRLDTVLH
TYARLPLNPVRQLAMRQAAEWILARQEADGGWGGIQPPWVYSLLALHLLGYPLDHPAMRA
GIEGLDGFVVREQTPDGEVRRLEACQSPVWDTALATAALLDAGVAPDDPAVLRATDWLLG
EQISAGGDWQVRRPRLEPGGWAFEFANDVYPDTDDTAEIVIALHQVSHPDQPRLDAAIER
AVRWTTGMQSADGGWGAFDADNTSILPTKLPFCDFGAVTDPPSADVTAHVVEMLAVLGRG
DERACRRGVRWLLDHQESDGSWFGRWGANHIYGTGAAVPALVAAGISPRSTAIRAAVRWL
EAHQNTDGGWGEDLRSYREPEWIGRGASTASQTAWALLALLAAEEHDSPAVRRGIDWLVR
TQRPDGGWDEDLFTGTGFPGDFYINYHLYRLVFPVWALGRYLRRQAERDGS
>A0A3M1DJT1|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MSWQASHSVSEDAVMPGGTGEVRQLRPYTLEDSVLAAREGLLREQQPDGHWVYELEADCT
IPAEYILMNHFLGEVDEELERRIAVYLRRHQMEEGGWPLFHGGDFDLSCSVKAYYALKLV
GDDPRAPHMVRARNLILNHGGAAHANVFTRITLALFEQVPWRATPFIPAEVILLPKWFPF
HISKVAYWSRTVMVPLFVLTTLKPKAANPRGVDIRELFVTPPEEEQNYFRFTSTLSRAFY
FLDRAGTLLEKLVPAFLRRYAIRRCEKWFIERMNENHGIGGIFPAMVNVLESLAVLGYPP
DHPLRRQAREAIERLLVENGDEAYCQPCVSPVWDTALAAQALLESGPADDPALRKGLQWL
RDRQLRDEPGDWREACPGLEGGGWAFQYSNYFYPDLDDTSMVGWALHRASPQEHADALRR
AAAWTAGMQSKNGGFGSFEVDNTQYYLNAIPFADHGALLDPPTADVTGRCIALLSLVDRE
AYADNIERAIAFLRQEQEEDGSWFGRWGTNYIYGTWSVLTALEVAGVDMSAGWVRRAVEW
LLEVQNEDGGWGEGNDSYYPPRHRRPHRSTPYQTAWALLGLMAAGEGRSGAVQRGADWLI
RHQRGDGLWRDESFTAPGFPRVFYLKYHGYNRYFPLWALARFRRLQTAPAG
>A0A523K9Q4|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MRMQAFRELSAADAAVSATAPAVEHLDDGLASSIARAVEALRAEQFAEGYWSYEFEADCS
IPAEYILMMHFMDEVDAALERKIAVYLRSKQGQDDGWALYPGGELNLSATVKVYYALKLA
GHSPDTPHMARARAAILACGGAVNANVFTKIALALFEQIPWRGVPFIPVEIMLLPRWFPF
HISKVSYWSRTVMVPLFVLCTLKPSAANPRKVDVRELFTTPPEEERHYFPVRSILNRVFL
ILDRMGRGLHRLVPRFIRNLAVKRAESWVIERLNGTDGLGAIFPAMVNAHEMLSILGYNR
DHPYRVMTREALRRLLVEKPDHAYCQPCVSPVWDTGLACLALQEADDRGDHPNVLRGLDW
LLPRQLLDQVGDWSDRRPGLRGGGWPFQFGNDHYPDIDDTPVIAWSMLESGQDRYQESIE
RAAEWICGMQSANGGYGSFDADNTHYYLNEIPCADHGALLDPPTSDVTARCVVFLSKLDR
ARFRDTIDRALVFLYREQESDGSWFGRWGANYTYGTWSVLVAMEAAGESLRTPSIRRAVS
WLESVQRPDGGWGEDNYSYFDASEADQGADSTAYQTAWALLGLLAAGEVRSDAVRRGVAY
LEHSQGADGLWQDDSFTCPGFPRVFYLKYHGYTRYFPLWALARFRRVLKQT
>A0A5D0PPB2|squalene-hopene cyclase|EC 5.4.99.17|Microbispora tritici|TrEMBL
MTALLTAASRAATALEAARDHLLALQSPEGWWKGELRTNVTMDAEDLLLREFLGVRTAAE
TAGAARWIRSQQQAGGGWANFHDGPADLSTTVEAYTALRLAGDPPSAPHLRAAAALVRDL
GGVESTRVFTRIWLAMFGQWRWEDLPVIPPEIVFLPPWCPLNVYDWACWARQTIVPLTIV
TAHRPVRPLPFGLAELRTGRPARRGPRTGWDAAFAALDHVLHRYERRPLAGLRRAALRRA
AEWVVARQEADGSWGGIQPPWVYSLIALRLSGYDVSHPVMRRGLAGLDRFTIREDGSRRL
EACQSPVWDTALAVIALLDAGLPRDHPALDRAGEWLLREEIRGPGDWAVRRPGLTPGGWA
FEFDNDGYPDVDDTAEVILALGRWGRPAARDAVRRGLRWTAGMASRDGGFAAFDADNTRA
LCLRLPFCDFGAVIDPPSADVTAHVVEALAAEGLARSPVVRRAVTWLLRAQEPGGSWFGR
WGANHVYGTGAVLPALAAAGVPPAAPCVRRAVAWLEAHQHPGGGWGEDMRSYRDPAWIGR
GEPTASQTAWALIGLLAAGERGPSVERGVAWLAGTQRPDGTWDEPHYTGTGFPGDFFINY
HLYRLVFPVSALGRYLRAGKGGTP
>A0A7H8MX24|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces microflavus|TrEMBL
MTATTDGSTGAANLSAPPAGHPADTTTAADEVLDAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGILDPETTRAAALFIRGEQLGDGTWNTFYGGPSDLSATIEAY
VALRLAGDRPDEPHMARAATWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPAHPNPPRKLAPAASW
DGIFQRLDKGLHLYHRLAPRPLRRIAMNVAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMVEACQSPVWDTCLATIALVDGGLRPDHPAL
VRAADWMLAEEITRPGDWSVRRPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVHHPDP
ARLEAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLGSHPRTRRGIEWLLAEQEECGAWFGRWGVNYVYGTGSVVPALVAAGLPAAHP
SIRRAVTWLESVQNDDGGWGEDLRSYTEEKWIGHGESTASQTAWALLALLAAGRRDSRAV
ARGVTWLTGAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYAYGDPFADRT
GAAQGA
>A0A8J6WM74|squalene-hopene cyclase|EC 5.4.99.17|Nodosilinea sp. FACHB-141|TrEMBL
MQTQEPQQLTGIDSAIAAAQNYLLALQHPDGYWWAELESNVTITAEIVLLHKIWGTDGDR
PLAKAEHYLRSHQRDHGGWELFYGDGGDLSTSVEAYMALRVLGVPASDPALLKAKDFILQ
RGGISKTRIFTKLHLALIGCYDWRGLPSLPAWVMLLESPSPFTIYELSSWARGSTVPLLV
VFDQKPVYKIEPAVNLDELYAEGIANVRWELPKAGDWSDIFIWLDGAFKFAESINFTPFR
DEGLRKAEQWILERQEATGDWGGIIPAMLNSMLALRCLGYDVNDPVVRRGLRAIDNFAVE
TDDTYWVQACVSPVWDTALGMRSLTDSGLAPDHPSLVRAGEWLLEKQILDYGDWIVKNPQ
GKPGGWAFEFENRFYPDVDDTAVVAMALQDVTLPDEALKREAIARAVRWVATMQCKTGGW
GAFDIDNDQDWINAVPYGDLKAMIDPSTADITARVLEMHGRLCREPNLAARYASDLSAQR
LERGLTFLLNEQEADGSWFGRWGVNYLYGTSGALSALALIAPERCQGAIARGVNWLVSCQ
NPDGGWGETCRSYDDPALKGQGPSTPSQTAWSLLGLLDAGSSSAAAELAIEKGIRYLVET
QTPEGTWDEQEFTGTGFPRHFYIRYHLYRHHFPLMALGRYQLSHVPEA
>A0A5C4LUR3|squalene-hopene cyclase|EC 5.4.99.17|Amycolatopsis alkalitolerans|TrEMBL
MTRTVQSPAAVTLARAVEHLKGLQEGGGWWKGELETNVTMDAEDLLLREFLGILTAAETE
EAARWIRSQQREDGTWATFYGGPGELSTTIEAWVALRLAGDAPEAPHMRAAQEFVLAGGG
LENSRVFTRIWLALFGLWSWDELPNMPPELIFLPSWFPLNVYDWGCWARQTVVPLTIVAT
LKPVRPLPFGVDELRTGERPGKNLKPWTWSGAFEYLDKALHTYAKLPVKPMRGWAMRQAA
EWIIARQEADGSWGGIQPPWVYSLLALHLLGYSSDHPAMKAGLKGLDGFIIREETPDGRV
RRLEACQSPVWDTALAMIALHDAGEPADDPALVKAADWLLGEEIRVAGDWAVKRPTTPPG
GWAFEFANDVYPDTDDTAEIVLALRRTAFGDRPRMKEAIDRATVWLQGMQSSDGGWGAFD
ADNTRELTTKLPFCDFGAVIDPPSADVTAHIVEMLAAEGLTSTRECRRGVRWLLDAQEDN
GSWFGRWGANHLYGTGAVVPALVAAGVSPADPVIRRAVAWLAEVQNADGGWGEDLRSYRD
PAWIGKGDSTASQTAWALLALLAAGERESSIVERGVRWLAGTQRADGTWDEPQFTGTGFP
GDFYINYHLYRLVFPVSALGRYVRGAS
>A0A5C6WD01|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. ISID311|TrEMBL
MTATTDGSTGALPPRAPSASDATAEKTAASARTRSAVRDDTADAARRATARATDHLLSVQ
DPAGWWKGDLETNVTMDAEDLLLRQFLGIQDPELTEAAARYIRGEQCADGTWATFYGGPG
ELSATIEAYVALRLAGDAPDAPHMARASAWVREQGGIAAARVFTRIWLALFGWWKWDDLP
QLPPELLYFPKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPRRPNPP
RPLAPAASWDGVFQRLDKALHLYHKVAFRKLRRAAMRSAARWIIERQENDGCWGGIQPPA
VYSVIALHLLGYDLDHPVLRTGLASLDRFAVRRADGARMIEACQSPVWDTCLATIALADA
GVPADHPQLVQAAEWMLAEQIDRPGDWSVKRPQLPSGGWAFEFENDNYPDIDDTAEVVLA
LRRVKHPDPQRVEAAVRRAVRWNFGMQSKDGGWAAFDVDNTSPFPNRLPFCDFGEVIDPP
SADVTAHVVEMLADVGRTHDPRTRRGVAWLLAEQEPCGAWFGRWGTNYVYGTGSVLPALA
AAGIPRSHPAVRRAVRWLEGVQNDDGGWGEDQRSYRDKEQWAGRGASTASQTAWALMALL
AAGERDGEAVRRGVRWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRY
LNGGPAVAPVGA
>A0A7K1W1U4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. YIM 132580|TrEMBL
MTATTDGSTGAANLSATPAGHPADTTTAADDVLAAARQAAERSVAHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYEGPSDLSATIEAY
VALRLAGDRPDEPHMARASAWVREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPAEPNPPRKMAPAASW
DGLFQRLDKGLHLYHKVAPRLLRRIAMNVAARWIVERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMVEACQSPVWDTCLATIALVDGGLRPDHPAL
VKAADWMLAEEITRPGDWSVRRPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARLEAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLGSHPRTRRGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALVAAGLPAGHP
SVRRAVTWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDSRAV
ARGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRA
GVAKGA
>A0A838I6E1|squalene-hopene cyclase|EC 5.4.99.17|Chthoniobacterales bacterium|TrEMBL
MPPVSSNVIPLPSASPDASVYAPDLADLQEAIARAQQNLLRQQHPDGHWCGELIVDSTLC
SDYVLFMHWLGDVDEAMQQRCVRHILKRQLPDGGWNIYYGGPSEVNASVKAYFALKLAGH
SADLPFMHEARANILRLGGIPRMNTFSKLYLALLGQFPWQYLPSIPVEMILLPSWLPFNI
YKMSSWSRAMLVPLAIINHFKPTRELPGMQQLHELYPLGTEHKDFSLARDSRLLTWRNFF
LRGDHALKIVSKLGWHPMRQRALEEAERWMLERIGEGSDGLATVFPAMLNSLIALKAFGY
GSTHPAYRKAVADFRELFVEDEEDFRIQPCLSPVWDTAINIIALAESGVPADDPALRKAA
AWLVGKEVRVHGDWTVNNPHPEASGWAFEYNNVYYPDTDDTAMVLMGLRLVQPAEPGAID
EVFKRALDWQLSFQCRDGGWAAFDKEVTQHWLEDMPFADHNAILDPTCSDLTARTLEVMG
YIGFDTKQPCVRRAVQYLINTQDDDGSWYGRWGVNYIYGTWQVLRGLRAIDEDMSQTWIL
RGRDWLESCQNDDGGWGETCASYDDPTLKGRGESTASQTSWALMGLCACGDLDRPSVQRG
LRYLLSTQKRDGAWDEPQITGTGFPGVFYLKYDMYRQNFPLLALATFVNYRSGLGHRKSF
YRC
>A0A6P1ND33|squalene-hopene cyclase|EC 5.4.99.17|Bombella sp. KACC 21507|TrEMBL
MTKERSVSETMSYPGDLGNVVDRAIKSAHGALSNRQHEDGHWVFELEADATIPAEYVLLE
HFLDRIDPEKQKKIGVYLRRIQGSHGGWPLYHDGDFDISATVKAYFALKAIGDDPEAPHM
RRARKAILARGGAERTNVFTRIQLALFGEVPWDAVPVMPVELMLLSRKAYVSLWNMSYWS
RTVIAPLLVLGAYKPLAKNPKNIHVPELFVTPPAQVKDWIRGPYRSHWGRFFKYLDSVLR
KIEPHFPKKTRKKAIKKAIAFIEERLSAGGLGAIYPAMANVVMMYRILGVSDNDPKVVQA
WQSIQDLLIEKNGEIYCQPCVSPVWDTGLSGLAMLEAATGPKAVEREETFKNLKKSASWL
RDRQILDVKGDWAINTPHLRPGGWAFQYENDYYPDVDDTAVVGMLLHRLDPEENKEAIER
AREWIIGMQSTNGGWGAFDIDNDLDFLNQIPFADHGALLDPPTVDVSARCVSFLSQLGHP
EDRAVIEKAITYIRKEQEPSGSWFGRWGTNYIYGTWSALCALNIAGVDHQDPTILRAVEW
LESVQREDGGWGEDCASYEGAAQGVYKQSLPTQTAWAVLALMAVGRRDTEAVKRGIAYLT
KEQDEKGEWNENPYNAVGFPKVFYLRYHGYKQFFPLTALSRYRNLESSNSGRVEFGF
>A0A6G3YVS2|squalene-hopene cyclase|EC 5.4.99.17|Leptolyngbya sp. SIO1D8|TrEMBL
MQTTDPTQQRINELDQAIAAAQNYLLSIQTPEGYWWADLESNVTITAEIILLHKIWGTDR
DRPLAKAEKYLRSHQRDHGGWELFYGDGGDLSTSVEAYMALRLLGVPTEDPALLRAKDFI
LQRGGISKTRIFTKFHLALMGCYDWQGLPSLPAWVMLFEQPFPLTIYELSSWARGSTVPL
LIVFDQKPVYTVAPTITLDELYAEGIHNVRWELPQSGDWSDIFLWLDKGFKLAESVNFIP
FRDIAIQRAEKWVIERQEATGDWGGIIPAMLNSLLALRTLGYDVNDPIVQRGIQAVDNFS
VETEDIYWVQACVSPVWDTGLALRSLTDSGMASNHPALVRAGEWLINKQILDYGDWIVKN
PQGKPGGWAFEFENRFYPDMDDTAVIAMALQDLTLPDEAAKKAAIARAVRWIATMQCKTG
GWAAFDINNDQDWLNAIPYGDLKAMIDPSTADITARVLEMHGRLSQDTALATSYAADLSP
QRIARGLDYLIQTQETDGSWFGRWGVNYIYGTSEVLSALTLIAPEHCRVQIERGVAWLVS
CQNADGGWGETCRSYNDTTLKGKGPSTASQTAWALLGLLDAVDYADTAVNKVIQQGVLYL
LTTQKDDGTWDEAEFTGTGFPGHFYIRYHLYRHYFPLMALGRYQKLDLS
>A0A5J6J114|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces vinaceus|TrEMBL
MTATTDGAGTPGADPGITAPETVQGAQEAAARATRHLLARQDAAGWWKGDLETNVTMDAE
DLLLRQFLGIGDEATTQAAALFIRGEQRTDGTWATFHGGPPELSATIEAYVALRLAGDAP
DAPHMARASAWIRSHGGIAAARVFTRIWLALFGWWSWDHLPELPPELVFLPPWVPLNIYD
FGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDARRPYPAAKRPAPLASWEGAFQRMDK
ALHVYRRFAPRRLRKAAMDTAARWIIERQENDGCWGGIQPPAVYSVIALHLLGYDLAHPV
MRAGLESLDRFAVWREDGARMIEACQSPVWDTCLAAIALVDAGLEPDHPALVKAADWMLG
EEIVRTGDWAVRRPGLAPGGWAFEFHNDTYPDIDDTAEVVLALRRIKHPEPARVEAAIAR
GVSWNLGMQSGNGGWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTAHVVEMLAVEGKA
ADPRTRRGIAWLLAEQEPSGAWFGRWGTNYVYGTGSVVPALAAAGFAPAHPAIRRAVRWL
ESVQNEDGGWGEDQRSYKDPQWAGKGASTPSQTAWALMALLSAGEREGKAVRRGIAHLVE
TQRGDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLYGDPFAPGEA
>A0A841QH29|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter lovaniensis|TrEMBL
MNTISHPSKVKAAVSAPVSSTPSCVTPTPFTGMGNSLAHTVAAACDWLMGEQKADGHWVG
PVASNASMEAEWCLALWYLGLEDHPLRPRLGKALLHMQREDGSWGTYWGAGNGDINATVE
AYAALRSLGYAADTPELSKACAWIMRMGGLRNVRVFTRYWLALIGEWPWEQTPNLPPEVI
WFPNKFVFSIYNFAQWARATLVPLAILSARRPSRPLRPQDRLDALFPQGRESFDYVLPKK
EGVDLWSSFFRTTDRGLHWLQSRFLKRNTVREAAIRHMLEWIIRHQDADGGWGGIQPPWV
YGLMALHGEDYQLHHPVMAKALAALDDPGWRRDQGDASWVQATNSPVWDTMLALMALHDA
NAEERYTPQMDKALDWLLARQVRVKGDWSIKLPDVEPGGWAFEYANDRYPDTDDTAVALI
ALSACRNREEWKKKGVEDAITRGVNWLIAMQSSCGGWGAFDKDNNRSLLSKIPFCDFGEA
LDPPSVDVTAHVLEAFGLLGVPRQTPALQRGLAYIRAEQEASGAWFGRWGVNYLYGTGAV
LPALAAIGEDMTQPYITRACDWLIAHQQEDGGWGESCASYMDISSIGWGTTTPSQTAWAL
MGLIAANREQDHPAIARGCRYLIDRQEADGSWTEEEYTGTGFPGYGVGQTIRLDDPAVAK
RLQQGAELSRAFMLRYDLYRQFFPLMALGRAARIMPVGQ
>A0A7X3VD88|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
MTTRETPESSVSPGLLDAVSKAVSRSQDYFARTQSPGGYWWGELESNSTMEAEYLMLTHF
LGIGDEDTWRKLANHLLETQREDGTWGQYYGSPGDLSTSVECYFALKLAGLSPDDPRMIK
AREFILSKGGVPQARVFTKIWLALFGQWDWKRVPAIPPEMALLPSWVPMNLYDFSSWARA
TMLPLSIVMTHRPSCRIPNSAAISELFPNEQGKSPRPGSMEGAAGIFHIADRIFRWYDSF
PLHPVRRIAIRRAVKWIVDHQDKDGSWGGIQPPWVYSLISLKVLGYDLNHPVMRKGIEGF
RAFTIEENGAMRVQACVSPVWDTCLAMVALEDSGLPPDSPILRRAGEWLIRAQVADGGDW
QVRVKNTTPGGWAFEFANSAYPDIDDTAEALIALKSVDTEDPERQRKAIRRGAEWMLGMQ
SKNGGWAAFDKDNTRRAVAAIPFADFGEMIDPPSADVTAHVIEALVRVGYPADTGPLRKA
ARYLWNEQEEDGPWFGRWGVNYIYGTGAVLPALKAMGEDMSAGAVRRAVAWLVAHQNEDG
GWGES
>A0A7X3U785|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
MAKLIEQGMENRLREALERTQQYFFRTQHEDGYWWGELESNPTMEAEYIMLTHFLGSDEG
GRIPRVAEDIRRRQSADGSWRMYYGAPGDLSTSIECYFALKLAGDSPDAPHMAKARSFIL
TCGGVPKARVFTKIWLALFGQWDWKGTPAMPPDMMLLPRWAPFNIYRFASWARATIVPMT
IILTLHPTRPPHESAWVTELYPEGPVTFTLSRWKAKPFSLKGWFLVLDRAISIYRKLPFI
PGRKRAIKAAVDWIVRHQEADGSWAGIQPPWVYSLIALSAIGFPLDDPVISKGLEGFRRN
WSVPSEDGDALRVQACLSPVWDTCLAMRGLLDSGVPSNHPAIRRAAAWLIQEEIRVKGDW
AVYRPHLEPSGWAFEFDNVHYPDIDDSAIVVTDLAATRMRDDTGERARTEALDRAVNWLT
GMQCSNGGWAAFDWNNDSRELAKIPFADFGELLDPPSVDVTAHVLEMYAKLGYTVEHPAV
RRGLSYIWEQQEHDGPWFGRWGVNYIYGTGAVLPALEALGLDMTQPRVRRAVEWLLARQN
TDGGWGETCVSYADPSLRGQGESTPSQTSWALMALIAAGEAGHESVARGVEFLLERQQED
GTWDEPQFTGCGFPGYGPGERPNEYEPIDGPNSQGPELGAAFMIKYHLYRNYFPLSALGR
YAQSLNP
>A0A4R4G1J4|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia pyrrocinia|TrEMBL
MNDLTEMATLSAGIAPAGVDAAVARATDALLAAQNPDGPWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARKAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKALDKLLVVQEDEAYCQPCLSPVWDTSLAAHALLETGDARAEEAVLRGLDWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLRQSDAYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTSDVSGRCLSMLSQLGETAA
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLGPEDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLI
AEQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNATRVTVGM
>A0A6I4PY14|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. J1-007|TrEMBL
MTTTEPARPAGTAKNPPAAGRAATARTAAPAETGTAPAAAEAAAAPAVPAAAPAPAPGDR
TAAALHAAREHLLGLQSAEGWWKGELQTNVTMDAEDLLLREFLGIRTESETAEAAAWIRS
QQRDDGTWANFHDGPPDLSTTIEAYVALRLAGDRPEDAHMRRAAGYVTGAGGIEASRVFT
RIWLALFGRWSWDELPVMPPELMYLPTWCPLNVYDWACWARQTIVPLTIVGSLRPIRPLP
FDLPELRSGVRPRRRATGWGAAFNGLDRLLHRYERGPARLAPGRRLRRAAMRRAAEWIVA
RQELDGSWGGIQPPWVYSLMALHLLGYGLDHPVMERGLKGLDGFTVRDGKGRRMEACQSP
VWDTVLAMNALADAGLPADHPALMRAAGWVVAEEVRGPGDWSVRRPDLAPGGWAFEFHND
GYPDVDDTAEAVLALRRTAHPKAEAAVRRGIRWMTGMASKDGSYGAFDADNTRTLCTKLP
FCDFGAVLDPPSADVTAHVVEALAHAGHTDSPALRRAGAWLLKAQEKDGSWFGRWGANHV
YGTGSVVPALVAAGVPRDRPEIRRAVRWLADHQNTDGGWGEDLRSYGDPDWIGRGVSTPS
QTAWALLALLAAGERGPMVERGVGWLVDRQRPDGTWDEDHFTGTGFPGDFYINYHLYRLV
FPISALGRYLAARDAAGGPDTAAPAPEAASVPEAAPAPEAGPVPGAAPAPEAGPVPGAAP
APEGMA
>A0A7V1UKP1|squalene-hopene cyclase|EC 5.4.99.17|Acidobacteriales bacterium|TrEMBL
MQPAPGQSPELFFGVLDNAAAKVRAAIDATRDYLFSIQHEEGYWCGELEADTTLESDYIL
LHTLLGTVDEKRNAKAAREILRHQNEDGGWPIYHGGPSNISASVKAYFGLKLAGYTVDHP
ALVRARKKILDMGGVTEVNTFTKIYLCFFGQYSYEAVPAIPPEIVLFPRWFWFNIYEISS
WSRAILVPLSIAYAKKPFKKIPQEMAIDELYLGGREHADLHLKWAKKIISWRNFFLVLNH
MTHWFERVHIRPLRSLALKRAEKWMLERFEMSDGLGAIYPAMMNAIIALRCLGYSLDDPQ
VIRAVDEFEKLGIEEEDTFRMQPCMSPVWDTAYALFALGESEKGSPTHSPDPRLIRAAEW
MLKKQVTHKGDWAVKVRNAAPAGWYFEFNNEFYPDVDDSAMVMLGLSKVRTSNERYHDES
VRRAIDWVLAMQCRNGGWASFDKDNDKMVFQYVPFADHNAMLDPATVDITGRVLEMLAGH
GCTQKDRCVQRALEFIRKEQEPDGSWFGRWGVNYIYGTMCVLRGLDAIGIDHNEPMVQQA
AEWLRMFQNADGGWGETCGSYDDPNTRGIGPSTPSQTAWAVLGLLAAGDTRSEAVQKGVA
YLLKTQRKDGSWAEPQYTGTGFPRVFYLAYHLYRNYFPLMALTSYERAFGKAN
>A0A7S7UED6|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. CCBAU 53340|TrEMBL
MDSVNATSREALESSIASATQGVLGFQQSDGHWVFELEADCTIPAEYILLRHYLAEPVDT
ALEAKIGNYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDSVDAPHMVRAREAIH
ARGGAINSNVFTRFLLATFGVVTWRAVPVLPIEIVLLPFWSPFHLNKISYWARTTMVPLM
VIAALKPRARNPLGVGIDELFLQDPHSIGMTAKAPHQSMAWFVLFRALDAILRVVEPMFP
KSLRKRAIDAALAFIEERLNGEDGMGAIYPPMANIVMMYDALGKDENFPPRAITRRGIDK
LLVFNGDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLDWLIPKQELEVKGDWA
AKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGATGYDAAIDRGREWIEGMQ
SDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGQTEKTSKQVAG
GIAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDHKDPMIRKAAAWLASIQNKD
GGWGEDAVSYRLDYKGWEAAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIATQNEKG
LWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A385AT49|squalene-hopene cyclase|EC 5.4.99.17|Micromonospora sp. B006|TrEMBL
MTTVTAEAVGKAVAAGAEALFRRRRPDGAFGDDPPASVLGTAGAVAALHAADPAGSADLV
GAGTAWLRRQQHDDGGWGGVVGAGTAVVPTAVAIAALALTAPSDSAEAIAAGRARLAALG
GVDTITDPAISLLCRQLLTMAGMTAEAGPLRRLPLEIVLFDRVRRQRLSFRTAPFIGLAL
MQADLLPTGRLRRATLRRARPAALRLLRSIHDHEGGTGALSEDPWPAALVLLGLARSGEA
PDIAHAVVGWLREAVRPDGAWDAVTNLDLTRTGYAATGLIAAGYADDPRLRATREFLHAG
RKPEAFEVLDVPPGGWSYSNARGWPVTLESAEILSALAGFPGAGADPVLRDGLAWLVGRQ
DSRGSWSLWVRDTRLANDGPCPAITSQAILALHDAGHPDEDPAITRAAAWLLTRAAPDGT
FENLWYRDHTSGTAVVVGALSRVGHARHEVVRRAARWLRDTQLPDGSWGPGDGTAGSVEE
TSWAVQGLLATGDPDATGAVDRGVAWLVAAAGPDGTWPAARVCNYIRHHMRYPNAVITQA
LALRALGEYRGASAARPDVAPDAVAR
>A0A0S1UEX7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. FR-008|TrEMBL
MHQGDAMTATTNGPAGAAPSRPAPARTTAATTDTAALDGAAVEAAAERARARAADHLLGL
QSPEGWWKGDLDTNVTMDAEDLLLRQFLGIRDEATTRSAALFIRGEQREDGTWATFHGGP
PDLSTTVEAYVALRLAGDSPDAPHMTRAAHWVRSQGGIAEARVFTRIWLALFGWWPWDRL
PELPPELIFLPPWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPADPAP
RARFAPLASWNGAFQRLDRALHAYRKVAPRALRRAAMATAGRWIVERQENDGCWGGIQPP
AVYSMIALHLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALAD
AGVPADHPQLVRAADWMLDEQIERPGDWSVRRPHLAPGGWAFEFHNDNYPDIDDTAEVVL
ALRRVRHPDTARMERAISLGVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDP
PSADVTAHVVEMLAAEGLAADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPAL
VDAGLPTTHPAIRRAVAWLESVQNDDGGWGEDLRSYREQGRMARGASTASQTGWALMALL
AAGERESRAARRGVTFLAETQHEDGSWEEPYYTGTGFPWDFSINYHLYRQVFPLTALGRY
TRGAAPEGA
>A0A7Z7JB09|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus taiwanensis|TrEMBL
MSMNETAFANPAPQVGPAQRQPAAPQEAPAARLPAPALDRGIDRALDALLHQQRPDGHWV
YELEADATIPAEYVLMVHYLGEDPDRDLEARIARYLRRIQNPDGGWPLFHQGRSDISASV
KAYFALKMAGDDPQSAPMQRARQAIHAMGGAEATNVFTRTLLALYGVLPWKAVPMMPVEI
MLLPRWFPFHLSKVSYWARTVIVPLLVLNSLRPQARNPRGVGINELFVGNCHTVGLPPRA
AHQHAGWYTVFRGLDALLRLAEPLFPRTLRRRAIAAAQRFVSERLNGEDGLGAIFPAMAN
SVMMFDVLGVPPEDPARAVARRSIERLLVEHGDEAYCQPCLSPVWDTALATHALLETGEA
RAAQAAGRALDWLRPLQVLDLRGDWAVRRPLVRPGGWAFQYANAYYPDVDDTAVVAAAMD
RFMRAHHAPGRYGEAVARATEWIVGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDPP
TADVSARCLSMLCQTGATPANSEPAARALRYLLAEQMPDGSWFGRWGTNYIYGTWSALCA
LNAAGLPPEAPELRRAVAWLARIQNADGGWGEDGSSYRLDYSGYEPAPSVASQTAWALLA
LMAAGAAQHPAVARGIDYLLRTQQPGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWALA
RYRNLQRGLGDHGGNSGQVAWGL
>A0A853DHW0|squalene-hopene cyclase|EC 5.4.99.17|Allobranchiibius huperziae|TrEMBL
MTPVLASGSVAGDVDATSDPRSAARAALDAAIAHLSSLQHEQGWWKGDLATNVTMDAEDM
MLREFLGIATAETRDQSARWIRSQQREDGTWATFFGGPGNLDTTVEAWVALRIAGDQATA
PHMLRAQQFVRAQGGVERSRVFTRIWLALFGLWDWRDLPNLPPELIHLPRWFPLNVYDWG
CWARQTIVPLTVVCTLRPRRPLPFAIDELRTGAELEAFAPWSTVGGAFQRADVLLHAYAK
RPLRQLRTGAMRRAAEWIIARQEADGGWGGIQPPWVYSILALHLLGYPLEHPVLRAAVDG
LEGFVITEDTDEGPIRRVEACQSPVWDTALAVNALLDSGISGDDARVRRAADWLAREQIT
GDGDWQVRRPGIPSGGWAFEFANDVYPDVDDGAEVVMALRRVGSNRPTLLRRGVDRGIAW
TAGMQSKDGGWGAFDADNTRTLATHLPFCDFGAVIDSPSADVTAHVVEMLAAEGRARGER
CRRGVAWLLEHQEPDGSWFGRWGANHVYGTGAVVPALVAAGIPADHNAIRASVRWLGEHQ
NADGGWGEDLRSYRDPDWIGHGASTASQTAWALMALVAAGEADDGGGVVERGIAYLAGTQ
RADGTWDEDLYTGTGFPGDFYINYGLYRLIFPIWALGRYVGGGPA
>K4QT88|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces davaonensis (strain DSM 101723 / JCM 4913 / KCC S-0913 / 768)|TrEMBL
MTATTDGSTGALPPRAAAASETSTTPVAAGVHDAAVHAVRRATEHLLSRQDAEGWWKGDL
ETNVTMDAEDLLLRQFLGIRDESTTRASALFIRGEQREDGTWATFYGGPAELSATIEAYV
ALRLAGDEPEAPHMARAAEWIRAQGGIAAARVFTRIWLALFGWWKWEDLPELPPELIYFP
TWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPANPNPLKPLAPVASWD
GAFQRLDKALHQLRKVAPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVIALHLM
GYDLQHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHPQLV
KAADWMLGEEIVRPGDWAVRRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHDPE
RVEKAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVVE
MLAVEGLAHDPRTRRGIQWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALVAAGFPGSHPA
IRRAVAWLESVQNDDGGWGEDLRSYQDTRGWSGRGASTASQTAWALMALLSAGERESKAV
ERGVEWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFAEAK
GG
>A0A7X3IF61|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus sp. HJL G12|TrEMBL
MRKILSAVNEEIEKLSECLIQQQKPDGTWHFCFENGIVIDAYVIILFRILDIQNETLIRQ
LHDRILGAQQRDGFWSLYADEEEGNLSATVEAYYALLYSGYSKDNEEPIQRAKSYIRSKG
GLGKVTSILTKAILAATGQIKWPLSVSLIPLEILLFPNYFPINYFDFSGYSRVHLTPMLL
MANRHFSVQSAHAPDLSDLKDPRFDEDEPFSREYEEMQEDIRAGQNRLIGTPRSIHESAR
NKAEKFMLQRIESDGTLYSYASSTILMIFALLALGYDHRHPIIMRAIQGLSEMQCRTERF
ITIQNSPSTVWDTALLTYALQEAGFADDHTSIQRAASYLLSRQHQKTADWSIHNPDTVPG
GWGFSDTNTLNPDVDDTTAALRAIHGLSGIDRVYQESWNRGLNWVMSMQNKDGGWPAFEK
DTHKEMLTWLAIDGAKFAAIDPSEADLTGRTLEYLGNFAGLDMRHAFIKRGTNWLIHHQE
KDGSWYGRWGVCYIYGTWAALTGLQAVGLPVNHDAIQKGAKWLLSIQNPDGGWGESCQSD
RLMRYVPLGESTPSQTAWALDALIAVHPQPTTAIDQGILRLITNLHEDDWKSSYPTGAGL
PGNFYSHYHSYRYIWPLLTLSHYRMKYS
>A0A7W2UHH0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. GMR22|TrEMBL
MTATPTVQPSESSEPKTLSAAREATARAVDHLLSRQDERGWWKGDLETNVTMDAEDLMLR
QFLGIQDPDTLDAAARYLRSQQATDGTWATFHGGPPELSATIEAYVALRLAGDEPDAPHM
AAASAWVRSRGGIASSRVFTRIWLALFGWWRWEDLPELPPEIIYFPKWLPLNIYDFGCWA
RQTIVPLTIVSARRPVRPAPFPLDELHTDPRRPNPPRPLAPVASWDGVFQRLDRALHAYH
KVAFRPLRRAALRSCARWIVERQENDGCWGGIQPPAVYSLIALHLLGYDLDHPVMRAGLE
SLDRFAVWREDGSRMIEACQSPVWDTCLAAIALADAGLAPDHPALVKAADWMLTEQIDRP
GDWSVRRPGLPSGGWAFEFHNDNYPDIDDTAEVILALRRVDHPEPERIEAAVRRAMRWTL
GMQSKNGAWGAFDVDNTSPLPNKLPFCDFGEVIDPPSADVTAHVVEMLAHEGRTYDARTR
RGISWLLAEQEPSGAWFGRWGTNYVYGTGSVVPALIAAGVPASHPAVRRAVRWLESVQNE
DGGWGEDQRSYLDAEWMGRGASTASQTAWALLALLAAGERDGAAVERAISWLVRTQRQDG
SWDEPYFTGTGFPWDFSINYHLYRQVFPVTALGRYVHGEPTGARPRSG
>A0A7X1ZJ30|squalene-hopene cyclase|EC 5.4.99.17|Roseospira navarrensis|TrEMBL
MQWSPARDGRPTPAQDNAPGADPTLNPTLGGTEGHGPREDGASDPGVPDPGVIDRVIDEV
SGWLRKRQNDDGHWVFELEADATIPSEYILLNHFLDEIDDAREQKIAVYLRRIQGAHGGW
PLFHDGDFDMSASVKAYYALKLVGDHPDAPHMVRAREAILKRGGAARANVFTRYTLAMFG
QVPWRACPVARVEAMLLPRWFPFHLDKVSYWSRTVMVPLFVLYSRRARAVNPRGVEVSEL
FVTPPEKERKYHSNPTGHWMGSLLLKVDAIARLFEPLFPVSGERKATEKALKFVEERLNG
VDGLGGIYPAIANCLMVYHTLGYPKDHPHVRTARKAVDGLIVDKGDHAYVQPCLSPVWDT
GLASLAMQETIAQGRGGLSDAAPAAQDSAIAGACAWLRDRQILDTVGDYAAWKPGLRPGG
WAFQYNNAHYPDVDDTAVIGMLLDRARDPKNKEAIDRAAEWIAGLQSRNGGWGAFDADNE
YYVLNHIPFADHGALLDPPTVDVTARCVGFLAQIGDPKYTPVIDRALAFLKSEQEPDGSW
FGRWGTNYIYGTWSALAAFNAVGEDPQAPHIQAAVAWLKRRQQADGGWGEGCESYWADKR
DFVKASTPTQTSWAVLGLMAAGEVDSDAVRKGIAYLSHAPREEGRWTEELYNAVGFPRIF
YLKYHGYPAFFPLWALSRYRNLTRGNSRRVSWGI
>A0A7D6ETX8|squalene-hopene cyclase|EC 5.4.99.17|Thermosynechococcus elongatus PKUAC-SCTE542|TrEMBL
MPTPLAAAIDPKQLQQAIRASQDFLFSQQYAEGYWWAELESNVTMTAEVILLHKIWGTEQ
RLPLAKAEQYLRNQQRDHGGWELFYGDGGDLSTSVEAYMGLRLLGVPATDPALVKARQFI
LARGGISKTRIFTKLHLALIGCYDWRGIPSLPPWIMLLPEGSPFTIYEMSSWARSSTVPL
LIVMDRKPVYAMDPPITLDELYAEGRANVVWELPRQGDWSDVFIGLDRVFKLFETLNIHP
LREQGLKAAEEWVLERQEASGDWGGIIPAMLNSLLALRALDYAVDDPIVQRGMAAVDRFA
IETETEYRVQPCVSPVWDTALVMRAMVDSGVAPDHPALVKAGEWLLSKQILDYGDWHVKN
KKGQPGGWAFEFENRFYPDVDDTAVVVMALHAVKLPAENLKRRAIERAVAWIASMQCRPG
GWAAFDLDNDQDWLNAIPYGDLKAMIDPNTADVTARVLEMVGRCQLAFDSSALDRALAYL
RNEQEPEGCWFGRWGVNYLYGTSGVLAALSLVAPRYDRWRIRRAAEWLVQCQNADGGWGE
TCWSYNDPSLKGKGDSTASQTAWAIIGLLAAGDATGDYATEAIEKGIAYLLQTQRADGTW
HEDYFTGTGFPCHFYLKYHYYQQHFPLTALGRYARWRNLLAS
>A0A6P0RZE2|squalene-hopene cyclase|EC 5.4.99.17|Symploca sp. SIO2D2|TrEMBL
MQTQDSITTESTESIAEAMAKAQNYLLNLQYPEGYWWAELESNVTITSEVVLLHKIWGTD
QARPLHKVEAYLRSQQREHGGWELYYGDGGDLSTSVEAYMALRLLGVPATDPALLKAKKL
ILERGGISKTRIFTKFHLALIGCYDWRGVPSIPPWVMLLPEQFLFSIYEMSSWARGSTVP
LLIVFDHKPIYQTNPAITLDELYTEGASNVRFELPRNGDWTDLFVTLDDTFKLAEDLDFV
PFRQEGLEAAERWVLERQEVTGDWGGIIPAMLNSLLALRSLDYDVTDSVVVRGLEAVDNF
AIETAETYTIQPCISPVWDTAWVIRALVDSGIAPDHPAVVQAGEWLLSKQILGYGDWAVK
NPQGKPGGWAFEFENRFYPDLDDSAVVVMALDAVQLPQEDHKRTAIARAVAWMASMQCQE
GGWAAFDINNDADWLNYLPYADLKAMIDPNTADVTARVLEMLGSCNLSIEQGKLERSLTY
LLEEQEDDGSWFGRWGVNYIYGTSGALSALSVITPEKHRLSIEKGANWLVGCQNADGGWG
ETCRSYDDPKLKGQGDSTASQTAWALIGLMAAGEATGNRATEAIDQGINYLVTTQLPDGS
WQEDYFTGTGFPSHFYLKYHFYQQYFPLIALGRYLK
>A0A067Z7J3|squalene-hopene cyclase|EC 5.4.99.17|Gluconobacter oxydans DSM 3504|TrEMBL
MLIYSDILEKEDRVSETLSRQSVEPDEINHAIEGAQAALGGKQKSDGHWVYELEADATIP
AEYVLLEHYLDRIDPEKQAKIGVYLRRIQGDHGGWPLYHDGGFDLSATVKAYFALKAIGD
DINAPHMRIAREAILDHGGAARTNVFTRIQLALFGEVPWDATPVMPVELMLLPRKAFFSV
WNMSYWSRAVIAPLLVLNALRPKAINPRGIHVQELFVKPPSEVKDWIRGPYRSVWGRFFK
HLDSALRPVLPLIPRSVHKKALKAASDFIEPRLSRGGLGAIYPAMANVVMMYRAQGVPDS
DPRAKTAWDAIQDLLVDHGDEIYCQPCVSPVWDTGLSGLAMIEAASGPAGTKTKETLVAL
KKSAEWLREHQILDVKGDWAINAPDLRPGGWAFQYENDYYPDVDDTAVVAMLLHRVDPEN
SREAISRAREWIIGMQSTNGGWGAFDIDNDHELLNHIPFSDHGALLDPPTADVSARCISF
LAQLGDPDDRPVILKAIEYLRSEQEPEGCWFGRWGTNYIYGTWSVLCALNIAGVPHDDPM
VLRAVNWLESVQRPDGGWGEDCATYEGGTAGTYKKSLPSQTAWAVLALMAVGRRESEAVK
RGVAYLVSQQNEKGEWQEEAYNAVGFPKVFYLRYHGYKQFFPLTALARYRNLGVSNSGKV
EYGF
>A0A3S2V7A6|squalene-hopene cyclase|EC 5.4.99.17|Novosphingobium umbonatum|TrEMBL
MSEAVDKAQLEASLQRATQALLNEQRADGHFLYELEADATIPAEYILLRHFLGEPVDGVL
EGKIGTYLRRIQSGVHDGWPLYDGGAFDISASVKAYFALKMIGDDTEAPHMARARAAILQ
AGGAEAVNVFTRIQLALFGAGPWETVPTIPPELILAPRWFPVHLLKMSYWARTVVVPLLV
LCALKPVARNPRGVLVPELYTGIPQKLTSQAEHVHPLWKAGFEALDRILKRMEGKWPHRM
RQRAIQMCHDWVVERLNGEDGLGAIYPAMANAVMMFAALGVEEDHPHRAIARVALDRLLV
VKEHEAYCQPCVSPVWDTALAAHALLEVGSVEAQAAAHEALDWLAPRQITQVVGDWAEQR
PDVAPGGWAFQYSNDYYPDLDDTAVVAMAMHRASDQRGGKDEAAVDRAAQWCLGLQGHDG
GFAAFDADNVAHYLNNLPFADHGALLDPPTADVSARVVSMLAQLGEPLDSPRMQAALRWL
EKEQEPEGSWFGRWGVNHVYGTWSVLCALGRAGIAVEHPMVARAVAWLKLVQNADGGWGE
SCDSYALDSKGHQTFISTACQTAWACLGLMAVGQARSEAVARGMAWLVAHQREDGLWGQE
AYTGGGFPRVFYLRYHGYPRYFPLWAMARYRRMVQGNQERPEWGM
>A0A3R9UMU9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. WAC01280|TrEMBL
MTATTDGSAGAVGPRAAAASTTHDTDASAPDLDGNAARAAERAVEHLLARQDPAGWWKGD
LETNVTMDAEDLLLRQFLGILDADTLRAAALHIRREQREDGAWATFYGGPGEVSATVEAY
VALRLAGDAPEAPHMARASAWVRARGGIAAARVFTRIWLALFGWWRWEDLPQLPPELLFL
PKWFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPARPNPRRPLAPATGW
DGIFQRLDKALHVYHRVAPRALRGTAMNVAARWIVERQENDGCWGGIQPPAVYSVIALHL
LGYDLQHPVMRAGLDSLDRFAVWREDGSRMIEACQSPVWDTCLATIALADAGLRPDHPAL
VKAVDWMLDEEITKEGDWTVRRPGLPPGGWAFEFHNDNYPDIDDTAEVLLALRRVDHPDP
ARVEAAIARGARWTLGMQSRNGAWGAFDADNTSALPNKLPFCDFGEVIDPPSADVTAHVV
EMLAYEGQARNPRTRRGIEWLLAEQEPNGAWFGRWGVNHVYGTGSVVPALTAAGLPGSHP
AIRRAVAWLGSTQNEDGGWGEDLRSYEDEQWIGRGASTASQTAWALIALLAAGDRESEPV
RRGVAWLTETQREDGSWYEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPSPQAA
RAARSAHAVRSSRSTAEEG
>A0A7C3MPY5|squalene-hopene cyclase|EC 5.4.99.17|bacterium|TrEMBL
MSEALQQVENGEIRVDDGVRHEFLDRVGFAIDRAQRSLIGQQHPDGYWHGALEANAEMNA
EYIIFMHYMDAVDRELEGRLKKFLLETQQADGSWALFKGGEGYLSSTIEAYFALKLAGMR
AGDEPMMQSRRWILSRGGISKAGTLARFYLAAMGQVPWDATAALPVEVALLPNWFFFNMY
ELASWARGTAFGLMLLQAARPVVPIDFRNGVLELYIEPPHFTRFKQPPGNGLFSLRNLFN
LIDRGLRFYDRHHLKSLRARALRAAENWILEHQEANGTWGGIEPCYLLSAMALKALGYRN
DHPVLKKALVGVRELIWEMGDRAMCMPCVSPNWDTALAAKALLDSGLPAGHPALVQSAKW
FIDHQIFKRGDWSVKRPDLEPGGWAFEFYNDWYPDVDDSAVILEVLARTEFPDAQAKERS
IRAGANWVMGMQSSDGGFAAFDADVQKKWLNQIPLADVEAVIDPSCPDLAGRVLEMMAAV
GYSAEHPVARRAIAWLKRSQSPDGAWWGRWGVNYIYGTWSALMGLRAIGVDLGESWVRRA
VAWLKSHQNEDGGWGESPLSDKDPAWRGRGPSTASQTAWAMMGLLAGEDGISEHVMRGAR
WLVERQNESGGWDELEFTGAGFPNHFYLRYHLYAHYFPLMALGRLRKRLLEGGAKVDQA
>A0A7Y3J816|squalene-hopene cyclase|EC 5.4.99.17|Steroidobacteraceae bacterium|TrEMBL
MNAAPSPLLGADPRLDGAISAARDALLARQDERGHWLFELEADCTIPAEYVLMMHFLDEI
DTALEPKIGEYLRAHQADHGGWPLYHGGEFNISCSVKAYYALKLIGDDADAPHMRRARAA
ILKAGGAARANVFTRIALALFGEIPWRGVPYIPVEIMLLPRWFPFHLDKVSYWSRTVMVP
LFVLCTRKPCAKNPRQVHVRELFTTPPELERDYFLECRQRGGLLPLVFLGIDRLFRTLDP
LIPKAMRAAAMKRAENWMLERLNGEDGLGAIFPAMVNALEVMTILGYPADDPRRVTAKKA
LQKLLVETDVSAYCQPCVSPVWDTALAALAMQECGDEASIAAANRALDWLLPHQLLEDAG
DWRINRRGLAGGGWAFQFANPHYPDLDDTAVVAWAMHQSSKSGEYAGSIRRALDWLVGMQ
SSNGGFAAFDVDNTHYRLNQIPFADHGALLDPPTSDVTARVLTLLARVARPEDRRARERA
IEHLRHEQEADGSWFGRWGTNYVYGTWSVLTAFAQAGVGPHDPAVRRAVEWLKSRQNADG
GWGESNDSYSSPHTTVPSTPHQSAWALLALAAAGEARSEAMRRGAGYLMDAQGRDGLWSD
PHFTAPGFPRVFYLRYHGYSAYFPLWALAAYRTHTHREATR
>A0A7L4Y885|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. QHH-9511|TrEMBL
MTATTDGSAGAVGPRAAAASSTTDTAPAAAGLQEVVARATQGSTTDTAPAAAGLQEVAAR
AAQRSVSHLLGRQDAEGWWKGDLETNVTMDAEDLLLRQFLGIQDEDTTRAAALHIRGEQR
EDGTWATFHGGPGELSTTIEAYVALRLAGDLPDDPHMARAAAWIRERGGIASARVFTRIW
LALFGWWKWDDLPELPPELIFLPKWFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPL
DELHTDPARPNPAKALAPAASWDGVFQRLDKAMHLYHRVAPRRLRTAAMNVAARWIVERQ
ENDGCWGGIQPPAVYSVIALHLLGYDLNHPVMRAGLESLDRFAVWREDGSRMIEACQSPV
WDTCLATIALADAGLPPDHPALVKAADWMLGEEIVRPGDWAVRRPGLPPGGWAFEFHNDN
YPDIDDTAEVVLALRRVKHHDPDRVEGAIARGARWTLGMQSRNGAWGAFDADNTSPFPNR
LPFCDFGEVIDPPSADVTAHVVEMLAYEGKAHDPRTRRGIEWLLAEQEPNGAWFGRWGVN
YVYGTGSVVPALTAAGLSRSHPAIRRAVAWLESVQNEDGGWGEDLRSYRQQAWIGHGAST
ASQTAWALLALLAAGGRQSKAVERGVAWLAETQLPDGSWDEPYFTGTGFPWDFSINYHLY
RQVFPLTALGRYVNGEPNLSREA
>A0A6B3H9N2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8455|TrEMBL
MTATTNGPAGAAPSRPAPARPTTDTTTAPDSATVEAAAERARARAADHLLGLQSPEGWWK
GDLDTNVTMDAEDLLLRQFLGIRDEATTRAAALFIRGEQREDGTWATFHGGPPDLSTTVE
AYVALRLAGDSPDAPHMTRAAHFVRARGGIAEARVFTRIWLALFGWWPWDRLPELPPELI
FLPPWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPANPAPRTRLAPLA
SWNGAFQRLDRALHTYRKVAPRALRRAAMAAAGRWIIERQENDGCWGGIQPPAVYSMIAL
HLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALADAGVPADHP
QLVRAADWMLDEQIERPGDWSVRRPHLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHP
DTARLERAISLGVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDPPSADVTAH
VVEMLAAEGLGADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALIDAGLPAT
HPAIRRAVAWLESVQNDDGGWGEDLRSYRDQGRMARGASTASQTGWALMALLAAGERESA
AARRGVAFLADTQHEDGSWDEPYYTGTGFPWDFSINYHLYRQVFPLTALGRYTRGAAPEA
A
>A0A3S0U1Y2|squalene-hopene cyclase|EC 5.4.99.17|Hyphomicrobium sp|TrEMBL
MNFDSATQSARLASGNPMREIGAPDIENAISNAKNALLSLQREDGHFVFELEADATIPAE
YVLMRHYLAEPVDAALEAKIANYLRRIQSDDGGWPLFHDGESNISASVKAYFALKMIGVG
TEEPYMKKARGWILSQGGASHSNVFTRNLLALFGQVPWTGVPVMPVEIMVLPRWFPFHLD
KISYWARTVVVPLTVLNALKPRARNPKGVGIAELFTIPPEDVKVWPKGPHQKSPWSEIFG
AIDRVLRVSEPFFPKSIRKRSIDKAVAFVDERLNGEDGLGAIFPAMVNALLVYDALGYSH
DHPNYRTARGSIEKLLIVKDDEAYCQPCLSPVWDTALSTHALMEVGGTEAEASAERALEW
LKPLQVLDTVGDWAESRPGIRPGGWAFQYANPHYPDTDDTAVVVMSMDRSLGRAPQADNS
YREAIERGREWIVGMQSKNGGWGAFDADNTYEYLNQIPFSDHGALLDPPTADVSARCVSM
LAQLGERRGQSYVLDNAISYLERTQEKDGSWYGRWGMNYVYGTWSVLCALNAAGVDPASS
VVRKAANWLLTIQNPDGGWGEAGDSYKMDYKAYEPAPSTASQTAWALMGLMAAGEVDHPA
VQKGIAYLASSQGSDGFWNEKHFTATGFPRVFYLRYHGYSKFFPMWALARYRNLKASNSR
SVTVGM
>A0A4R0KTF7|squalene-hopene cyclase|EC 5.4.99.17|Kribbella pittospori|TrEMBL
MTAERLAQDEKADVRVENCLDAAVEYLRSLQHEDGWWKGDLATNVTMDAEDLMLRRFLGV
ATAQTDAETARWIRSQQRDDGTWATFPGGPGDLSTTVEAWVALRIAGDDPAESYMAKAAE
FIRGAGGVEKARVFTHLWLALFGLWEWDDCPDLPPELIFLPSWAPLNVYNWACWARQTIV
PLTIVSALRPVRPVDFGVDQLRAGTPVARKAGLWTLDGAFQRLDVVLNAYTRWGPRGPLG
GIRRLAMQRSVEWIVARQEADGGWGGIQPPWVYSLIALHLMGYATDHPVMAAGLRGLEGF
TVHADTADGPVRWLEACQSPVWDTGLVVGALLDAGVAPDDKAVLRATDWLLDEQIDAPGD
WQVRRPTLTTGGWAFEFANDGYPDTDDTAEIVLALRRVVHPEPQVLRAALDDAVEWTTGM
QSADGGWGAFDADNTDTTPLRLPFCDFGAVIDPPSADVTAHVVEMLAAEGKTGTDECRRG
VRWLLDSQEEDGSWFGRWGTNHVYGTGAVVPALIAAGTSAEDPVIRRAVRWLADHQNPDG
GWGEDLRSYVDPSWIGRGDSTPSQTAWALLALLAADERDETVRRGVGFLVDTQRPDGGWD
EHRYTGTGFPGDFYIGYHLYRLVFPIWALGRYLGKDRPHHEGTVSR
>A0A7T0JN70|squalene-hopene cyclase|EC 5.4.99.17|Methylomonas sp. LL1|TrEMBL
MFTESPIDTSSHDMPNSTTSTPNILSGLNAAIERAQSKLLSLQNPAGYWVFELEADCTIP
AEYIMMMHYLDDINEELQSKIAVYLRSRQAEDGSYPMFTGGPGDISGSVKVYYALKMAGD
SIHEPHMKRLREWILSQGGAARANVFTRIALAIFEQLPWRGVPYIPVEIMLLPSWFPFHL
DKVSYWSRTVMVPLFIMCTLKAKAKNPHNVSILELFVVHPDEEKHYFPERTLLNKFFLGL
DQLGRVTEPLIPKSIRKRAIDKAVDWFTERLNGEDGLGGIFPAMVNAYESMLLLGFPKDH
PNVLIARQSIDKLLVIKDDHAYCQPCLSPVWDTGLASLALLEADKQGNKTSLGRAYDWLK
SVQLSDEPGDWRVRRPELAGGGWAFQFANPHYPDVDDTAVVAFSMAEAEQSGLDESIHRA
TRWIVGMQSQNGGYGAFDVDNTYYYLNEIPFADHGALLDPPTVDVSARCAMLMARVTKDH
AEYLPALQRTIDYIRNDQEADGSWFGRWGTNYIYGTWSALLGLEQTSLPKTDPMYTKAAA
WLKSVQREDGGWGEDNLSYHDDKKFRGRYHFSTAFQTAWAVLGLIAAGEVHCREVKAGIE
FLLRHQQADGVWNDPCFTAPGFPKVFYLKYHGYDKFFPLWALARYRNELAKQ
>A0A7W9PXM9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces echinatus|TrEMBL
MKIAERARPAPLPLPEEVSPDEVHQATARLTAYISGRTDDDGAIREQCESRVLESALALS
LMTRTGTDSPARDRLLTYLRGHQESPDKLDRVLASCAVAAAAGRRADGDSTLVDTLAAGV
LGAAPGFISTRRRLMVYAVLSVLGCPLPADAELPGGGQVPTDPLHSWAAVQQASITLILA
GALGVRNRATEAALDTLLATDPADTVWEGYALMHLLVLHALAGVPGHEETVRRGLTTLLR
HQRTDGGFPFVLEMHNWCTSTGGLALHAAGADPALLRRMAATLGAQRGGAPLRSLSRGEA
LTGGWSMSPVVAQNDVDDTSCALEFLQAVDPVAHAGAVRGGVAALLAVQGADGGFPTYVA
GASSEPCMTAAAVCALGPHPATAPQRAKALAFLADHQFADGGFEPGWSRSRLHSLFRVRL
AACTADPGDARSAAMAERIERTVRETQNTDGGWGMQPGDPSDDISTAYGLITLLHADDPR
PVGAALTWLLQRQKADGSYGGPPDMVGPRPFAYHFPLLTDIPVLLALGHTRARVRDLRGS
LQGVR
>A0A4S2UG20|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. A0958|TrEMBL
MTATTDGSTGAVDPRAASASRQTTEPTIAADGVLTAARRAAERSVEHLLGRQDEQGWWKG
DLATNVTMDAEDLLLRQFLGIQDPATVRAAGRYIRGEQLGDGTWATFHGGPGDLSATIEA
YVALRLAGDRPEDPHMARAAGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMF
FPKWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPDHPNPPKRPAPAAS
WDGLFQRLDKALHVYHRFAPRRLRRSAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVAPDHPA
LVKAADWMLGEEIDRPGDWAVRRPRLEPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPE
PARVDAAIARGVRWNVGMQSRNGAWGAFDADNTSAFPNRLPFCDFGEVIDPPSADVTGHV
VEMLAVEGHAGHPVTRRGIEWLLAEQDVSGGWFGRWGVNYVYGTGSVVPALIAAGLPAAH
PAIRRAVDWLESIQNDDGGWGEDLRSYVEEKWIGQGASTASQTAWALLALLAAGRRDTVA
VTRGIAWLTETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFAGR
TATREEA
>A0A8I0QLY7|squalene-hopene cyclase|EC 5.4.99.17|Gluconobacter sphaericus|TrEMBL
MLIYSDILEKEDRVSETLSRQSVEPDEINHAVEGAQAALGGKQKSDGHWVYELEADATIP
AEYVLLEHYLDRIDPEKQAKIGVYLRRIQGDHGGWPLYHDGGFDLSATVKAYFALKAIGD
DINAPHMRIAREAILDHGGAARTNVFTRIQLALFGEVPWNATPVMPVELMLLPRKAFFSV
WNMSYWSRAVIAPLLVLNALRPKAINPHGIHVQELFVKPPSEVTDWIRGPYRSVWGRFFK
HLDSALRPVLPLIPRSMHKRALKAASDFIEPRLSRGGLGAIYPAMANVVMMYRAQGIPDS
DPRAKTAWDAIQDLLVDHGDEIYCQPCVSPVWDTGLSGLAMIEAASGPAGTKTEETLAAL
KKSAEWLRERQILDVKGDWAINTPDLRPGGWAFQYENDYYPDVDDTAVVAMLLHRVDPEN
SREAISRAREWIIGMQSTNGGWGAFDIDNDHELLNHIPFSDHGALLDPPTADVSARCISF
LAQLGDPDDRPVILKAIEYLRSEQEPEGCWFGRWGTNYIYGTWSVLCALNIAGVPHDDPM
VLRAVNWLESVQRPDGGWGEDCATYEGGTAGIYKKSLPSQTAWAVLALMAVGRRDSDAVK
HGVAYLVSQQNEKGEWQEEAYNAVGFPKVFYLRYHGYKQFFPLTALARYRNLGASNSGKV
EYGF
>A0A3S0TGW3|squalene-hopene cyclase|EC 5.4.99.17|Sphingomonas sp. TF3|TrEMBL
MSIDTIDRSALLDEADATASKAAAALGGLQNADGHWVFELEADATIPAEYVLLRHYLGEP
RDAEIERKIGVYLRRIQSPTHHGWGLFHGGAFDVSASVKAYFALKMIGDSIDAPHMVQAR
TAIHKAGGAAAANVFTRIQLALFGAGPWSVVPTLPVELILLPRWFPVHLSKMSYWARTVI
VPLLVLAAKKPVARNPSGVLVDELYTAKRAKLVSKAAGTKQAWTTFFNGLDVVLKGVEPL
WPKGTRQRAIDASVTFVTERLNGVDGLGAIYPAMANSVMMFDCLGYPQDHPARALARESV
EKLLVVKEDEAYCQPCVSPVWDTALASHAMLEAGGEEAEARAAAGLAWLKPLQVLDVKGD
WADEKPDVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRAKDRTPAAYDESIARGVEWTVGL
QSRDGGWGAFDADNSYHYLNNIPFADHGALLDPPTSDVTARVVSMLAQLGETDTPRMKAA
LAFLEKEQMSDGSWFGRWGVNYIYGTWSVLCALNAAGLDAKHPMVRKGADWLIHIQNLDG
GWGEDCESYALDYKGYTPAPSTASQTGWALLALMAAGKVDHPAVERGIRHLIATQAADGL
WGQEKYTGGGFPRVFYLRYHGYPAYFPLWAVARYRNLKRSNDPRPAFGM
>A0A2X3KE12|squalene-hopene cyclase|EC 5.4.99.17|Frankia sp. Ea1.12|TrEMBL
MNVSDTVSVTRESIPTQTSAGDATARDRTAAAGSGLTHALRLATDHLLALQDGTGWWKFD
LETNTSMDAEDLLLREYLGIRTAEVTAASARFIRSRQSDDGSWPQYFGGPGELSTTVESY
IALRLAGDDASAPHMLSAATWVRDHGGVPATRVFTRIWLALFGWWRWEDLPVLPPEIMLL
PRRAPLNIYSFGSWARQTLVSLTVVSALRPVRPAPFDLDELYPDGPASAGSSAGPGGGGS
GAGASGVLERISTRFTAKEIFLGIDRLLHVYHRRPVRSMRNHALRAAERWIIARQEADGC
FGGIQPPAVYSIIALRLLGYELDHPVLKAALRALDDYTVTLADGSRMVEASQSPVWDTAL
AVNALADAGATAAIAPDHPALVRAADWLLGQEVRHRRGDWAVNHPDVPASGWAFEFENDT
YPDTDDTAEVLLALRRVRHPARDELDAAERRAVAWLFGLQSSDGGWGAYDADNTSTIPYQ
IPFADFGALTDPPSADVTAHVVELLAEAGLGGDDRTRRGVDWLLDHQEADGSWFGRWGVN
YVYGTGSVMPALRAAGVEPSHPAMRAGADWLLTHQNADGGWGEDLRSYTDPEWSGRGEST
ASQTAWAMLALLTVGDQPEVSGALARGARWLADHQRPDGSWDEDQFTGTGFPGDFYINYH
GYRLLWPIMALGRYLRG
>A0A6L3VKM8|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura montaniterrae|TrEMBL
MTATEPTGTTASTASTGTTGTTGTRTAAEAMAAARDHLLGLQAPEGWWKGELQTNVTMDA
EDLLLREFLGIRTADDTREAARWIRSQQAPDGTWANFHDGPPDLSTTVEAYVALRLAGDE
PDAPHMRRAAAFVRGEGGIPATRVFTRFWLAMFGHWPWDELPVVPPEMVFLPRWFPLNVY
DFACWARQTIVPLTVVAAKRPVRPLPFELEELRSGRPVRRGRRGLPGWDEAFGALDKVLR
VYERRPLPGLRKAALRRAGEWIIARQEPDGSWGGIQPPWVYSLLALHLLGHGLDHPVVRR
GLDGLERFTIRDAKGRRLEACQSPLWDTVLAMNALVDAGVPGDHQALEAAAGWVVGEEVQ
GPGDWSVRRPDLPPGGWAFEFDNDYYPDTDDTAEAVLALSRVGHPEAEPAIERGVRWMAG
MVSRDGGFGAFDADNTRALCRRLPFCDFGEVIDPPSADVTAHVVEALSHRGMADSTLVKR
AVVWLLKAQEDDGSWFGRWGANHVYGTGSVVPALVAAGVRPEKPAIRRAVRWLERHQRED
GGWGEDLRSYRDPEWVGHGVSTASQTAWALLALLAAGERGAAVERGVRWLVEHQRPDGTW
DEEHFTGTGFPGDFYINYHLYRLVFPLSALGRYVKGIGS
>A0A6M9XUF0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces coelicolor|TrEMBL
MTATTDGSTGASLRPLAASASDTDITIPAAAAGVPEAAARATRRATDFLLAKQDAEGWWK
GDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDSPEAPHMARAAEWIRSRGGIASARVFTRIWLALFGWWKWDDLPELPPELI
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPARPNPPRPLAPVA
SWDGAFQRIDKALHAYRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPEDHP
QLVKASDWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHH
DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAVEGLAHDPRTRRGIQWLLDAQETDGSWFGRWGVNYVYGTGSVIPALTAAGLPTS
HPAIRRAVRWLESVQNEDGGWGEDLRSYRYVREWSGRGASTASQTGWALMALLAAGERDS
KAVERGVAWLAATQREDGSWDEPYFTGTGFPWDFSINYNLYRQVFPLTALGRYVHGEPFA
KKPRAADAPAEAAPAEVKGS
>A0A6G3CQC2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5614|TrEMBL
MTATTDGSTGAANITGAPADDPTDTRTAADDVTDAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPGTTRAAALFIRGEQLGDGTWNTFYGGPGDLSATIEAY
VALRLAGDRPDEPHMARASGWIRDQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPDHPNPPRKLAPPTSW
DGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMIEACQSPVWDTCLATIALADAGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARLESAIARGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDF
>H6RL60|squalene-hopene cyclase|EC 5.4.99.17|Blastococcus saxobsidens (strain DD2)|TrEMBL
MPAPSPSTTAPGRLAAPPRGREGAAATALAAGRDWLLARQEPGGWWQGELETNVTMDAED
LLLREFLGIRTDAETAETAAWIRSRQRDDGSWATYTGGPGDLSTTVEAYVALRLAGDDPG
SAHLRRAAGFVVAHGGLEASRVFTRFWLAMFGEEPWARLPVLPPELVLLPRRMPLNVYDF
ASWARQTIVPLAVVGALRPRRPLPFGLAELRAGAAPPARPVSPVGRAFLGLDRLLHRYER
RPLKGLRRLALARAERWILERQEADGSWGGIQPPWVYSLIALHLLGHPLDSPAVQAGLAG
LDRFTVRSGGLRRLEACQSPVWDTALTVLALTDAGVPGDDPALRRAAGWLVGEEIRIRGD
WSVRRPDLVPSGWAFEFDNDWYPDVDDTAEVALALCRTAAAEADGGPARAAVDRGVAWLV
GMQSRDGGWGAFDADNTSRLCRHLPFLDFGEVTDPPSADVTAHVVETLAHTGAAGSPAAR
RGVDWLLDAQEPDGSWFGRWGVNHVYGTGAVVPALVAAGVDPGARPIRRAVSWLEEHQGA
DGGWGEDPRSYTDPAWRGRGRPTASQTAWALLALLAAGERGPAVERGIGWLTATQRPDGS
WDEPEFTGTGFPGDFFINYHLYRQVFPLMALGRYLGEGRTR
>A0A6I5EBG1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5469|TrEMBL
MTATTDGSTGALPPRAASASEPHDTIPQAAGSVGIQDAAARATQRATDFLLSRQDAEGWW
KGDLETNVTMDAEDLLLRQFLGIQDEKTTRAAGLFIRGEQRADGTWATFYGGPGDLSATI
EAYVALRLAGDGPDEPHMAKASAWIRERGGIASARVFTRIWLALFGWWKWDDLPELPPEL
IYFPKWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHADANDPNPAKPLAPM
VSWDGLFQRLDVALHTYRKVAPRRLRKAAMNTAARWIIERQENDGCWGGIQPPAVYSVIA
LYLLGYDLEHPVMREGLASLDRFAVWRDDGARMIEACQSPVWDTCLATIALADAGVPADH
PQLVRAADWMLGEEIVRPGDWAVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKH
HDPERLDNAIRRGVRWNLGMQSKDGGWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTA
HVVEMLAFEGLSHDPRTRRGIQWLLSAQEANGSWFGRWGVNYVYGTGSVVPALVAAGLPA
SHPAIRRAVTWLETVQNDDGGWGEDLRSYPEAAEWSGKGASTASQTGWALLALLAAGERE
SKAVERGIEWLAQTQRPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPL
VEVKGG
>I4HBY4|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa PCC 9807|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSDGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPANDPTLEKAREFI
LAQGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKSNNWSDVFLWLDGLFKWAEKTNLVPFR
QESLKAAEKWVIERQEDPGDWGGIIPAMLNSLLALKALDYDVDDPIVARGLKAVDNFAIQ
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKGVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYRQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A6H1K7B1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. RPA4-5|TrEMBL
MTATTDGSTGALPPRAPSASDATAEKTATPAPARTAVRQDTVDAARRATARATDYLLSVQ
DPAGWWKGDLETNVTMDAEDLLLRQFLGIQDPKLTEAAARHIRGQQGADGTWATFYGGPG
ELSATIEAYVALRLAGDVPDAPHMARAAAWVRAEGGIAAARVFTRIWLALFGWWKWDDLP
QLPPELLYFPKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPRHPNPP
RPLAPATTWDGVFQRLDKALHVYHKVALPGLRRAAMRSAARWIVERQENDGCWGGIQPPA
VYSVIALHLCGYDLDHPVLRAGLDSLDRFAVWREDGTRMIEACQSPVWDTCLATIALADA
GVPADHPQLVKAAEWMLAEQIDRPGDWSVKRPQLPSGGWGFEFENDNYPDIDDTAEVVLA
LRRVRHPDPLRVDAAVRRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPP
SADVTAHVVEMLADVGRTHDPRTRRGIAWLLAEQEPDGSWFGRWGTNYLYGTGSVLPALA
AVGVPGSHPAVRRAVRWLERVQNDDGGWGEDQRSYQDKERWAGRGASTASQTAWALMALL
AAGERDSQPVRRGVRWLAATQREDGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRY
LGGGPGGVPVES
>A0A536Z947|squalene-hopene cyclase|EC 5.4.99.17|Betaproteobacteria bacterium|TrEMBL
MYSSSRELRLKADREAVARRAPVGPVESSLERGIEAASAALLGLQRADGHWVFELEADAT
IAAEYVVLQHFLGEPNPALEAKIAIYLRRLQGPHGGWSLFYGGDLNISASVKAYFALKLA
GDAPESAHMLRARDAILAHGGAGTTNVFTRILLALFGVISWGAVPIIPVEIVFLPQWFPF
HLSRVSYWSRTVLVPLLVLQALKPRARNPRGIRIDELFPGRRPRARRWARAAHQSRARFA
VFAAIDAALRLAEPMIPQGIRRHAIKKAVAFVTERLNGEDGLGAIFPAMANTVMMFDALG
YARDHPYFVTARRAIDKLLVVTREEAYCQPCVSPVWDTVLVCQSLLEVGDKEARTAARGG
LAWLEKRQVLDAVGDWADQRPQVRPGGWAFQYANPHYPDLDDTAVVVMAMDRFARRRVVR
GEPDFRAAIDRGREWVLGLQSANGGWGAFDVDNTSEYLNHIPFADHGALLDPPTADVTAR
CVSMIAQLDNAADAPALAKALGFLRREQEDDGSWYGRWGMNYVYGTWSVLCALNAAGIDP
QAPEVRRAVAWLVAAQNEDGGWGETGDSYGLDERGVEQAASTASQTAWALLGLMAAGEER
NAAVERGIDYLLRRQGADGFWREPQFTATGXXXLARYRNFTQSGERRARYGM
>J4SDK4|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia multivorans CF2|TrEMBL
MNDLTDMATLSAGTVPAELDAAVARATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRAVDHVLR
AVDGLFPAYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKSIEKLLVVHEDEAYCQPCLSPVWDTSLAAHALLETRDPRAEQAAVRGLDWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANPHYPDVDDTAVVAMAMDRAQKLNQSDTYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETAL
NSDAARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCALNAAGLGPEDARVKRAAQWL
LSIQNKDGGWGEDGDSYKLNYRGYEPAPSTASQTAWALLGLMAAGEVNNPAVKRGIDYLI
AEQKEHGLWDEARFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNTTRVTVGI
>A0A6I5RG67|squalene-hopene cyclase|EC 5.4.99.17|Leptolyngbya sp. SIO1E4|TrEMBL
MQTKDPQQITGLDQAIAAAQNYLLSIQNPDGYWWADLESNVTITAEIILLHKIWGTDRDR
PLAKAETYLRSQQRDHGGWELFYGDGGELSTSVEAYTALRVLGVPAHDPALVRAKDFILS
RGGISKTRIFTKFHLALIGCYDWRGLPSLPAWIMLLEQPFPVTIYELSSWARGSTVPLLI
VFDQKPVYVIDPTITLDELYAEGIENVRWELPQSGDWSDIFLWLDQGFKLAESLNFVPFR
DVAIQRAEQWIIERQEATGDWGGIIPAMLNSLLALRALDYDVNDPIVRRGIQAVDNFAIE
TEDIYWVQACISPVWDTGLALRSLTDSGLAPDHPALVRAGEWLLSKQILDYGDWIIKNPK
GKPGGWAFEFENRFYPDMDDTAVIAMALQDLTLPDEALKKAAIARAVRWIATMQCKTGGW
AAFDINNDQDWLNAIPYGDLKAMIDPSTADITARVLEMHGRLSRDAALAKSYAADLTPER
IVRGLNYLLQTQESDGSWFGRWGVNYIYGTSEVLSALTLIAPERCRVSIERGVAWLVSCQ
NSDGGWGETCRSYTDPSLKGQGPSTASQTAWALLGLLDAADYADAAANRAIQTGVDYLLT
SQTENGTWNEAEFTGTGFPGHFYIRYHLYRHYFPLMALGRYRHRRALS
>A0A7V7CTP1|squalene-hopene cyclase|EC 5.4.99.17|Rhodospirillaceae bacterium|TrEMBL
MFADSLIESPALQEELQKAVAASAAALMARQRADGHWVFALEADVTIPAEYVLFLHYMDE
RDKALEQKIGVYLRAKQADHGGWPLFHGGEFNISASVKAYFALKALGDDIEAPHMRRARQ
AILEHGGAAASNVFTRTLLALFEQIPWHGVPVMPVEIMLLPKWFPFHLDKVSYWSRTVIV
PLIVLMSLKPKARNPLKINIKELFVMPPDQVRDWNLEPVRSRWAYFFRGLDRVLQRLSPY
FPSSLRARAVAKAVAFVDERLNGEEGLGAIFPAMVNAVEMYDLLGVPASDPRMVIAKKAL
RKLVVDEGAFAWVQPCVSPVWDTSLACHALLEVGDEPSLAAARKGADWLVERQIRDVMGD
WAAQRPDLAPGGWAFQYANPHYPDVDDTAVVMAALDRLDRERYSEAIELGAVWLRGMQSL
GGGWGAFDAENTHYALNYIPFADHGALLDPPTADVSARCISALSVLPNGRDSRIVADGVD
YLLAEQEKDGSWFGRWGTNYIYGTWSALAALNAAGISHESLAVRRAVAWLLNCQKEDGGW
GEDGRSYWEDEPHGQAVVSTPSQTAWAVLGLMAAGQVAHPAVARGINYLMKSRNDEGLWD
EELFTAVGFPKVFYLRYHGYRAFFPVWALARYRNLTAGNAGPVLHAL
>A0A7T5CGV2|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MTTIDPPIEDRDVMGNEEQIPSLEEGIERGLDWLRENQHEDGFWAGQLESNSCMEAQWVL
AQHVMEVPRDEKYDGVIQSILSMQREDGSWEIYYDAPHGDVNTTVECYAALRVAGYEPSD
PILVKAREWIFKNDAMKRLRVFTRFWLSLIGEWKWKDCPTLPPELILLPSWAPMNIYQFA
QWGRATIVPLCILSARRYVKPLPANARLDELFPEGRDKFDYKLKVDVKAFSIENFFVLAD
KFLNVYVKSPVKPMRELAIKTCMEWILKHQDWDGAWGGIQPPWIYSLMAMRCEGYALDQM
NVKSGLEAFNTHWKIEREDGTFLQASDSIIWDTVLSLLAMLDCGLDAGKEESMKRAIDWV
LSKEITIKGDWSVVLKNVEPGGWAFERANQLYPDVDDTAVAILVLVKAKKYVDDVTKRRI
DDAVARAELWVRAMQCKNGGWGAFDKDNCKALVTKIPFCDFGEVLDPPSVDVTCHVIEAL
TELGHTQENDPALKKAVDYVKLEQEEEGSWFGRWGVNHIYGCGAVLPALRAAGEDMSSTY
VIKSGDWIVAHQNKDGGWGETCASYMDDELRGKGPSTASQTGWALMTLEAIDAERYGNSI
REGVQYLLRTQGDGTWYEPYYTGTGFPGYGIGERTDVTKQMGFMDQGKELARGFMINYNM
YRHYFPLMAMGRLVGKIKG
>A0A3L7R538|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MIFSRHNRDRGTAFSLTAQSSPSLVLAPTVRPSQRDHSSLQQERSRDSRSALDEAFVVQH
VPVHKEDRSRSTEAKLITNAMQRTQRWLYDRQLADGHWRGSLEGDTILESEYVIILAWAG
KLAAPEVKGAAQRILQEQLPSGGWAIYPGGPVDCSASVKAYLALKLTGHAQDSEPLNRAR
LAIARAGGPWSVNSFTRFYLALLGQMPYSACPAVPPEMVLLPSWFPINLHRVSAWSRTMI
VPLSLIWAFKPVRKVLKAEGIGELFATPEWLQAPQITAENGIWTKFFRVVDRVVKMSDAI
GFQPLRSRAVAECRRWMLQRFEGSDGLGAIFPPIVWSIVALRAMGCDDESAEVQECWRQL
AGLVEVESDGSVRVEPCRSPVWDTAITLRSLCDAGRAVKSSGTDRCLATEVASVTDLDQT
VDWLLDREVRTSGDWARRTDAIPSGWCFEYANRFYPDVDDTAMVLIALSTWQQSVAGLAA
QGTSAGLGRVARVHAAISRATPWLEALQNSDGGWGAFDRDNNCEILCKVPFADHNAMIDP
SSPDLAGRVLEAFGKIGLRLGHASVDRACDYLRLNQEADGSWFGRWGINFIYGTWQAIEG
LRSVGVPANDPAIVAAVEWLVSRQQSDGGWGESPASYSDPAMSGRGTPTASQTAWAVAAF
IAADRHDSRPAQRGVQWLVERQCVDGAWEENEFTGTGFPKVFYLRYHYYPIYFPLMALAR
FLTAEALAAAGRSRKEQVA
>A0A3L7TGN3|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MPEFFRGRLMPHIVPSRTSMPPSIELCTIPQMERHLERAVTALKSLQRADGHWCAELEGD
SILQSEYLLMKWILGQEREPLVDGRPAKTLLRLLAYLRTQQREDGGWGPYPGSSSDVSAS
VKAYFALKLFGDSPDAPHMKKARAVIRHLGGAERCNSFTNFFLAGLGQISWNAVPTIPPE
IMFLPKWCYFHLDKVSAWSRAMIVPLTIVSSKRHTREVPSDLGIGELFVDQDARHLLKAT
NAAPRGWKRFFLAVDGALKKLHNAGGTPWRQEAIHRAFEWIETRAGQDGAAATDGVAAIF
PSMVYWQIVLHALGYERTHPLVMRAERELDAFFVTLGHGEDAPIRVQPCFSPVWDTGIAL
YALADCGITVSDDSAARAAQWLVSKECTFAGEWQRNLDVPTAPSGWYFEYANAHYPDSDD
TAMVAMALIRIAPNDDASPIHAAAKRGVRWMMAMQNDDGGWAAFDRTQHRSVLDYVPFAD
HNAMQDPSCPDITGRVLECLAWHGYTTEHAAVRAGIAFIRARQEHEGCWFGRWGVNYIYG
TWQAVIGPIRCGVSRDEAWIQRAGAWIKSIQKADGSFGESADSYDDPSLKGVGPSTASQT
AWAAMVLQEIYGVDDLSLIRAIEWLCATQLDTQSAADPLSNPDGDPAGSWCETEFTGTGF
PKVFYLRYHLYRLYFPTMALGRYLAAHGRGLRGVRLFDKGERAALGL
>A0A845VR81|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO3I8|TrEMBL
MQTQDRIVNSGVTEAIANSQSYLLAQQYPDGYWWAELESNVTITAEIILLHKIWGTDKQR
PLHKAEAYLRSQQRKHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDSALVRARDFILR
RGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPEWFPFTIYEMSSWARGSTVPLLI
VFDQKPVFDIQPSINLDELYTEGADHAKFELPRNSDWTDLFVLLDHGFKLAEDLNLVPFR
KQGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPVVQRGLEAIDRFAIE
TPDSYRVQACVSPVWDTAWVLRAMVESGLEPDHPALVRGGEWLLQQQILDYGDWVVKNPQ
GKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLKQAAIARGLAWIASMQCNQGGW
AAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEMLGSCNLSIESQQLEKAIAFLIQ
EQEADGSWFGRWGVNYIYGTSSALSALSKIAPHTHQRSIERGAAWLVKCQNLNGGWGETC
LSYDDPSLKGLGISTASQTAWALIGLMAAGEATGNWARDAIERGVNYLVSTQQPDGSWDE
TEFTGTGFPSHFYLKYHFYQQYFPLLALGRYQMSVSS
>A0A8A8DGQ3|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia seminalis|TrEMBL
MIRRMNKTAPSSWSALDTAIARGRDALARLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDDRQERMARYLRANQRLDTHGAWALYVDGAPDVSCSVKAYFALKAAGDSEHAPHMIRA
REAILTLGGAARANVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNISIRELFVTPPDEERRYFPPASGMRKVFLALDRTVRHVEPL
MPKRLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMQVLGYPDDHPLRRDCEHAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVAVPDAGETASGALRELDARIARA
YDWLAERQVDDLRGDWIENAPADVEPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRTHRN
ADGTNPHAPRVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVS
GRVLLCFGVTNRPEERASRARCIDYVKRTQQPDGSWWGRWGTNYIYGTWSVLAGLALAGE
DKSQPYIARAIDWLRARQHADGGWGETNDSYLDPKLGGTNGGESTSNFTAWALLAQMAFG
DHESDSVKRGIAYLLSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRL
AGAAAPARAAAEATDTAIG
>A0A7X4BVX3|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp. SB0661_bin_20|TrEMBL
MDLLINFLGRLSQSFFPPAPHKAQPRHWNPRTPSLKLVSGNRGVAGDVECVQSRTAPATV
GHAEAVEEALSRSARWLLGQQHPEQGYWVQELEADTTLTSEYVMLRRYIGAVDTEQEARM
VRYLQGAQLEDGGWPIYTGAPMDVSASVKAYFALKLAGVPQDDPGMRRARQAILDKGGVV
SANVFTKIALALFGQYDWKGLPSMPPEVVLAPKKFAFNMYAISYWSRAVVIPLLIVFAVR
RECRIPAERGIEELFCTPRDQINYRYAPPFQKDPEFISWRNFFVWIDRILKVYEKYPLRS
VRKKAMKRAEAWLLEHMQGDGGLGAIYPAMANSIFALMALGYPASHPLVQKALREIEALE
IDTPDSAEGPSTLHLQPCHSPIWDTALTINALIERGLPVDHEALSHASSWLRSRQTQKVG
DWVVSSPGATPGGWYFQFENELYPDVDDTAAVLTALAKVSPLQPADRDEVIQRGLKWALA
MQSSNGGWGAYDRDNDQLIFNKIPFADHQSLLDPPTADLTGRCLEMLGALGYDRSHPAVA
PALEFLRREQEADGSWYGRWGVNYLYGTWCVVVGLQAIGEDMSAPWIRRAVAWVESKQNI
DGGWGESCLSYADRAWAGKGESTPSQTAWALLTLLTAGLSDSLSIARGVNFLLRHQLDNG
TWYEPYHVGTGFPRVFYLRYHGYSKYFPMWALAMYRNVRMHGQTRSQALQDVAQSARQRQ
S
>A0A652L9N8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. gb1(2016)|TrEMBL
MTATTDGSTGAANLRAVPASDPTEPTIAPDDISAVARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPDTLKAAARFIRGEQMGDGTWNTFYEGPPDLSATIEAY
VALRLAGDRPDDPHMRRAAGWVREQGGIAESRVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHADPACPNPPKPAAPAASW
DGVFQRLDKALHLYHKVAPRRLRRSAMNAAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMRAGLESLDRFTVWREDGARMVEACQSPVWDTCLATIALADAGVSPDHPAL
VKAADWMLAEEIVRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVSHPDP
ARVEAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGRAQDPRTRRGIEWLLAEQEATGAWFGRWGVNYIYGTGSVVPALIAAGLPAAHP
SVRRAVDWLTSVQNDDGGWGEDLRSYREEKWIGHGASTASQTAWALLALLAAGERETQSV
ERGVAWLANTQQADGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFATAA
GADTGKGA
>A0A4R4P2Z9|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura bangladeshensis|TrEMBL
MTTTEEAPGLTGAAAGALDAARAHLLGLQSPEGWWKAELETNVTMDAEDLLLRQFLGIRT
EAETAEAARWIRSQQRADGTWANFHGGPADLSTTIEAYVALRLAGDPPDAGHMLAAAKYA
RDAGGIEGSRVFTRIWLALFGQWSWDDLPVMPPELMFLPSRVPLNVYDWACWARQTIVPL
TILGSLRPVRSLPVDLAELRGGAVPPDGAKGWGRAFNALDRVLHVYEKAPVRPLRRAAMR
RAADWIIARQEADGCWGGIQPPWVYSLMALNVLGYGLDHPVVKRGLDGLERFTIRDEKGR
RLEACQSPVWDTVLAMNALGDAGAAPDDPALLRAAHWVVGEEVKGLGDWAVRRPDLPPGG
WAFEFDNDVYPDTDDTAEAILALRKVALPEAEAPIERAIRWLNGMASRDGGFGAFDADNT
RELCTKLPFCDFGAVIDPPSADVTAHVVEALSKEGLAESAVVKRAVVWLLKAQEADGSWF
GRWGANHVYGTGGVVPALIAAGVRPGKPAIRRAVAWLEEHQNPDGGWGEDLRSYDDPAWI
GRGESTPSQTAWALLALLAAGERSAAVDAGVRWLVDNQRPDGNWDEDQFTGTGFPGDFYI
NYHLYRLVFPISALGRYLEGAT
>A0A433HF59|squalene-hopene cyclase|EC 5.4.99.17|Peribacillus cavernae|TrEMBL
MNRLITSLKSDQSIDGSWDYPFETGISTDSYMIILLRTLEIHDEKLIQALTKRILSRQET
NGAWKLYHDKRTGNLPATLEAYYGLLYSGYIDKHDKRMRAARQFILSNGGIEKAGMFTKI
MLALTGQYSWPVIFPVPIEVILSPMSLPVNFYDFSVYARANLTPILIVGNKKFQIKTGRS
PDLSDLYVNREYHEGEDPFLGTNDSSEWRDLFTALTQGVQSLAGFPEHLKNTAFEKAKQY
MLGRIEPDGTFYNYFSSTFLMIFSLLSLGYPKNDPIIMKAVQGLISMASEIDGHIHMQYT
TADVWNTSLISYTLQEAGVPESAETIQKANRYLLSRQHYKYGDWAIHNPDTLPGGWGFSN
VNTIHPDVDDTTASLRAIGLLVQGKPQYDQAWGRGINWVLSMQNHDGGWPAFEKNVDKKI
LNLLPVQGAEFILLDPSTADLTGRTLEFLGNYTNLNKDHPSLKRGRKWLRNHQERDGSWY
GRWGICYLYGTWAAVTGLIASGKRPESSAIQKAAAWLKHIQNKDGGWGESCHSDTLKKYV
PLGESTLTDTAWAVDALIAASERSTPEIQRGIIYLIENGTRQDWTVQYPKGQGMGGAFYI
HYHSYRYIWPLLALSHYKKKFLTK
>A0A5J6G3R3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces kanamyceticus|TrEMBL
MTATTDGSTGAAPPRAASASQPLDTTAATAGTRDAAARAMQRSTDFLLSRQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDEPTTRAAALFIRGEQRDDGTWATFFGGPGELSATIEAY
VALRLAGDRPDEPHMVKASAWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELIYF
PKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHADARRPNPVKPLAPVASW
DGVFQRLDKALHVYRKVAPRRVRKAAMNSAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVLKAGLDSLDRFAVWRDDGARMIEACQSPVWDTCLATIALADAGVPADHPQL
VKAADWMLGEQIVRPGDWSVRRPGLTPGGWAFEFHNDNYPDIDDTAEVALALRRVKHPDK
ARMENAIERGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGKSHDPRTRRGIEWLLAEQEESGAWFGRWGVNYVYGTGSVVPALVAAGLPASHR
AIRRAVSWVESVQNDDGGWGEDLRSYRERGWAGHGTSSASQTAWALLALLSAGEREAKSV
ERGIAWLAETQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPFTGGS
GKGS
>A0A160FD04|squalene-hopene cyclase|EC 5.4.99.17|Anoxybacillus sp. B7M1|TrEMBL
MPDERNRLVALLKRAQASDGSWRHPFETGISTDAYMIILLRSLEINDEQLIQSLVERIES
RQENNGAWKLFYDEGDGNVSATVEAYYALLYSGYRRKSDPRLRAARRRILEMGGIENAHM
FTKFMLALTGQYRWPPFFPLPLEFLLLPPSFPLHFFDISVYGRANLTPLLVLLDNKYSRK
TSKSPNLSELLGMRGEGEDWREMRTDRGFLSYVKQSILGWPAHIRAAAKQRAIQYMLKHL
ETDGTFYSYFSATFLMIFALLSEGYSKDHPVIAQAIEGLKNFRCTIDGQTHIQYTTAHVW
NTALASYALQEAGVPPTDDAIQKANHYLLSRQHYRYGDWAIHNPYSPPGGWGFSDINTIN
PDLDDTTASLRAIYRMASEEGAFRQAWDRGISWLFSMQNDDGGFAAFEKNVDRRLWRYLP
IDGAEFLLSDPSTADLTGRTLEFLGTFARLTKDHPTVAYAVEWLMDHQEKNGSWYGRWGI
CYLYGTWAAITGMAAVGVPSTHSSMQKAIKWLLSIQNSDGGWGESCKSDSAKAYIPLRTS
TAVHTAWALDALVAVFDQPIPEMEAALRFLQQSLNSKDWTVSYPTGQGMAGGFYIHYHSY
RYVFPLLALSHYENKYGSFTSQKS
>A0A375HL02|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus neocaledonicus|TrEMBL
MPMNETALANPAPRVGAAQREPAGPAQAQATRAPAPALDHGIGRALDALLHQQRPDGHWI
YELEADATIPAEYVLMVHYLGEAPDLDLEARLTRYLRRIQNPDGGWPLFHQGRSDVSASV
KAYFALKMAGDDPQSAPMQRARQAIHAMGGAEASNVFTRTLLALYGVLPWKAVPMMPVEI
MLLPRWFPFHLSKVSYWARTVIVPLLVLNSLRPQARNPRGVGINELFVGNCHTVGLPPRA
PHQHAGWYTVFRGLDALLRVAEPLFPRTLRRRAIAAAQRFVRERLNGEDGLGAIFPAMAN
SVMMFDVLGVPPEDPARAVARRSLERLLVEHGDEAYCQPCLSPVWDTALATHALLETGEA
RAVQAAGRALDWLRPLQVLDLRGDWAVRRPLVRPGGWAFQYANAYYPDVDDTAVVAAAMD
RYMRAHHAPGRYGEAVARATEWIVGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDPP
TADVSARCLSMLCQTGATPARSEPAARALRYLLAEQMPDGSWFGRWGTNYIYGTWSALCA
LNAAGLPPAAPELQRAVAWLARIQNADGGWGEDGSSYRLDYRGYEPAPSAASQTAWALLA
LMAAGAAQHPAVARGIDYLLRTQQPGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWALA
RYRNLQRGQSDPSDPSDPSGQSGQVPWGL
>A0A6G3CZK1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5914|TrEMBL
MTATTDGSTGASLRPLAASASDTDITIPAAAAGVPEAAARATRRATDFLLAKQDAQGWWK
GDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDAPDAPHMARAAEWIRSRGGIASARVFTRIWLALFGWWKWDDLPELPPELI
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPARPNPPRPLAPAA
SWDGAFQRIDKALHAYRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPEDHP
QLVKASDWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHH
DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAVEGLAHDPRTRRGIQWLLDAQEADGSWFGRWGVNYVYGTGSVIPALTAAGLPTS
HPAVRRAVRWLESVQNEDGGWGEDLRSYRYVREWSGRGASTASQTGWALMALLAAGERES
EAVARGIQWLAATQREDGSWDEPYFTGTGFPWDFSINYNLYRQVFPLTALGRYVNGEPFA
KKSRASEAPAESAAAEVKGS
>A0A8J7DQV4|squalene-hopene cyclase|EC 5.4.99.17|Nodosilinea sp. LEGE 07298|TrEMBL
MQTQEPQQLTGLDRAIAAAQNYLLALQHPDGYWWAELESNVTITAEIILLHKIWGTDSKR
PMAKAEHYLRSHQRDHGGWELFYGDGGDLSTSVEAYTALRVLGVPASDPALLRAKDFILQ
RGGISKTRIFTKLHLALIGCYDWRGLPSLPAWVMLLESPSPFTIYELSSWARGSTVPLLI
VFDQKPVYKIQPAINVDELYAEGIGNVRWELPKAGDWSDIFIWLDGAFKFAEAINFTPFR
DEGIRKAEQWILERQEATGDWGGIIPAMLNSMLALRCLGYDVNDPVVRRGLRAIDNFAVE
TDDTYWVQACISPVWDTALGMRSLTDSGLAPDHPSLVRAGEWLLEKQILDYGDWIVKNPQ
GQPGGWAFEFENRFYPDVDDTAVVAMALQDVVLPDAALKREAIARAVRWVATMQCKTGGW
AAFDINNDQDWINAVPYGDLKAMIDPSTADITARVLEMHGRLCREPGLAARYARDLTAQR
LEQGLTFLLNEQEADGSWFGRWGVNYIYGTSGALSALALVAPERGQGAIARAVNWLVSCQ
NPDGGWGETCRSYDDPTLKGQGPSTPSQTAWALLGLLDVGCSRTAELAVQKGIRYLIETQ
TPEGTWEEQEFTGTGFPRHFYIRYHLYRHHFPLMALGRYQMQG
>B9B603|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia multivorans CGD1|TrEMBL
MIRAMNKSALSPWSALDTAIARGRDALARLQQPDGSWCFELESDATITAEYILMMHFMDR
IDDALQERMARYLRAIQRLDTHGAWDLYVDGAPDVSCSVKAYFALKAAGDSEHAPHMVRA
RDAILKLGGAARSNVFTRILLATFGQVPWRATPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNVAIPELFVTPPDQERHYFPPARGMRRAFLILDRVVRHVEPL
LPKRLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMDVLGYPEDHPLRRDCENAL
AKLLVTRPDGSVYCQPCLSPVWDTAWSTMALEQARSVAVPESDESARALDELDARIARAY
DWLATRQVNDLRGDWIENAPADTQPGGWAFQYANPYYPDIDDSAVVTAMLDRRGRMHRNA
DGSHPYAARVARALDWMRALQSRNGGFAAFDADCDRLYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTRRAEDRASLARAIDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALAGED
PSQPYIARALEWLRAHQHADGGWGETNDSYLDPALAGTNGGESTSNCTAWALLAQMAFGD
CASDSVKRGIAYLQSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GAAEARARSSSGRAPHAANTALA
>A0A7Y6HUR9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. CAI-21|TrEMBL
MTATTNGPAGAAPFRPAPARTTAATTDTADLDGAAVEAAAERARARAADHLLGLQSPEGW
WKGDLDTNVTMDAEDLLLRQFLGIRDEATTRSAALFIRGEQREDGTWATFHGGPPDLSTT
VEAYVALRLAGDSPDAPHMTRAAHWVRSQGGIAEARVFTRIWLALFGWWPWDRLPELPPE
LIFLPPWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPADPAPRARFAP
LASWNGAFQRLDRALHAYRKVAPRALRRAAMATAGRWIVERQENDGCWGGIQPPAVYSMI
ALHLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALADAGVPAD
HPQLVRAADWMLDEQIERPGDWSVRRPHLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVR
HPDTARMERAISLGVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDPPSADVT
AHVVEMLAAEGLAADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALVDAGLP
TTHPAIRRAVAWLESVQNDDGGWGEDLRSYREQGRMARGASTASQTGWALMALLAAGERE
SRAARRGVTFLAETQHEDGSWEEPYYTGTGFPWDFSINYHLYRQVFPLTALGRYTRGAAP
EGA
>A0A5C7VLU9|squalene-hopene cyclase|EC 5.4.99.17|Nitrosomonas sp|TrEMBL
MSRISQQFNDLINLKKIALKDTWFKSKATSPTSSSDVAQSELAQCITKARNALMALQNKD
GHWCFPLEADCTIPAEYILMMHFMDEIDVELEQKLAIFIREQQSEVHGGWALYYGGEFDL
SCSVKSYFALKIVGDSPDAPHMQRVRAAILERGGAASANVFTRLLLAMYQQIPWRGVPFV
PAEIILLPRWFPFHLRKVAYWSRTVMIPLSILCTLKAKAANPRKIGIRELFTVPPEEEQN
YFPVRTSLNRILLYVERLGSKLEPMIPTFIRKIALKRAEKWVIERLNGECGLGAIFPAMV
NAYEALTLLGYDAEHPYRKQCKAALQGLLVDEGRRAWCQPCTSPIWDTVLASLSLQEDSH
ADQEPVKQALDWTIQRQILDEPGDWREAKPNLPGGGWAFQYENPHYPDLDDTAAAAWALY
QADPEVYRFSLRRAADWLAGMQSSNGGFAAFDIDNTYYYLNEIPFADHGALLDPPSSDVT
ARCTGFLSLYGDPQHQQVVERGLAYLFNEQESNGSWFGRWGSNYIYGTWSVLEAMQLAKV
DRQHEAIRKAVQWLKSKQRPDGGWGETNDTYLDPRQAGEFNVSTSFQTAWALLGLMAAGE
VNSTAVQKGISYLMKTQADDHLWYEPWFTAPGFPRVFYLKYHGYSKYFPIWALIRYRTLT
TER
>A0A661KYM6|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MTSKELDNAISKALEYILSLQHDDGYWVFDFEADVTIPAEYILLQRFLGREIAQDIKERF
KNYILRRQSSDGGWPLYEGGDSEISASVKAYFALKLLGEDITMPHMAKAREKILRMGGAS
KVNVFTRTTLALFGQIPWHTVPYMPAEIMLLPKWFFFHLSKVSYWARAVIVPLLILYAKK
PVCKLEDKEGVRELFLEDPEDLRYLDKFVSGKPLKNAFILMDRFLRKFDPYFSRRLRDKS
VSLAEKWTIEHMQGEGGIGAIFPAMANAVMALKILGYPEDHPDYVRGIKALDDLVLERGN
EVFCQPCNSPIWDTCLSLCTILEAGVPEDHPSVKKAVEWLIGEQITDVKGDWAINAPYLE
PGGWAFQFENAIYPDVDDTSVVLISLLMARAMDRYKQNIEKGVNWIIGMQSSDGGWGAFD
IDNNYLYLNNIPFADHGALLDPSTSDLTGRCIELLALLGFSNNFPPISKALQFLKKEQER
FGAWYGRWGVNYIYGTFSVLMGLAQLGKNKSEPWIKRAVDWLRRCQNPDHGWGETCYTYN
DPRLAGKGKSTSSQTAWAILALLAAGDLESDELKKGIRYLIDTQNKDGAWDEEEYTGTGF
PRVFYLRYHGYRHYFPLWALSSYRRLINNGKTLEDEVRLSSPAELRLPALRYKR
>A0A7Y4U0K5|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MSSPSWSPSTKNEFLQSVENAITRAREYFEREQHADGYWYYPLEANATMDAEYIFFNHFM
GRVDEQKHRRLCEHMLSVQGEDGAWALFHKGPGHLGNTIEAYFALKLTGYAADHPALVKA
RAFILAKGGLAQAQVFTRIFLAYFGQFPWHGVPAVPVELNLLPPWFPVNIYEMSSWARGT
VVPLTIILARQPYIRIAPERGVSELWKDPPERSDLSFPRSFPGLSWESFFITVDKVLKFL
GRSPIKPLRPRALQKAERWVLDHQDVNGGWGGIQPAMLNSVMALHSLGYRDDHPAVAKGI
QAIEDFLMDTGGHLLFQPCVSPVWDTVWAVKALIDSGMPTDHPVVTKAANWIIDQQIFKP
GDWQVKNPELEPGGWAFEFANDWYPDVDDTAAILFTLKRVTGLDERKKDHALARGVHWTL
GMQSRNGGWGAFDTDNTLDLWNQMPFGDLKAMIDPPTADLAGRLLEMMGTFGYDKEFGRA
QRALTFLRNVQERDGSWWGRWGVNYIYGTWSVLVGLRAIGEDMTLPYVRRAVTWLKARQN
TDGGWGEDCLSYWEPERAGKGDSTPSQTAWALLGLLAAEEEMSDEVVRGVEYLLTQQASA
GSWSEDLFTGTGFPQHFYLRYYGYCNYFPLMALGAFRARARRG
>A0A371XPV3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. AcE210|TrEMBL
MTATTDGSSGAAAPGATSATTAQLTDTSPGAAGTHDAATRAVQRATDFLLARQDAQGWWK
GDLDTNVTMDAEDLLLRQFLGIGDEATTRAAGLFIRGEQRDDGTWATFYGGPGELSTTIE
AYVALRLAGDAPDEPHMAKASAWIRERGGIAASRVFTRIWLALFGWWKWDDLPELPPELI
YFPKWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDARNPNPAKPLSPVA
SWDGAFERLDKAMHLYRKVAPRRLRKAAMNSAARWIIERQENDGCWGGIQPPAVYSVIAL
HLLGYDLEHPVMKAGLESLDRFALWREDGARMIEACQSPVWDTCLAVIALADAGLPADHP
RLVKAADWMLGEQIDRPGDWSVRRPRLASGGWAFEFHNDNYPDIDDTAEVVLALRRVRHP
DPVRMEKAIARGVRWNLGMQSRNGAWAAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTGH
VVEMLAVEGMSHDPRTRRGIEWLLAEQEPNGAWFGRWGVNYVYGTGSVLPALTAAGLPPS
HPAVRRAVAWLESVQNDDGGWGEDLRSYRYEDWKGHGVSTASQTGWALMALLSAGERDSK
AVERGAAWLTETQLEDGTWDEPYFTGTGFPWDFSINYHLYRHVFPLTALGRYVHGEPFAD
QASLPGKGS
>Q3M418|squalene-hopene cyclase|EC 5.4.99.17|Trichormus variabilis (strain ATCC 29413 / PCC 7937)|TrEMBL
MRTQDRVQVNSIAEAIAASQKYLLSLQNPTGYWWAELESNVTITAEVVLLHKIWGTDKTR
PLHKIEAYLRSQQKQHGGWELFYGDGGELSTSVEAYMALKLLGVPATDPAMIQARDFILQ
RGGISKTRIFTKFHLALIGCYNWRGLPSLPAWVMLLPNQFPVNIYEMSSWARSSTVPLLI
VFDQKPVYQVNPAITLDELYAEGVENVRYELPRSGDWTDLFLTLDEGFKLAESFNFIPFR
EEGIKAAEKWIIERQEATGDWGGIIPAMLNSMLALRVLGYATNDPIVERGLQAIDNFAIE
TADCYRVQPCVSPVWDTAWVIRALIDSGMAPDHPAIVKAGEWLLQKQIFDYGDWNVKNRQ
GQPGAWAFEFDNRFYPDVDDTAVVVMALHAAKLPHEQLKQKACDRALQWVASMQCKPGGW
AAFDIDNDQDWLNAVPYGDLKAMIDPNTADVTARVIEMLGACNLSIDSHDLERALTYLLN
EQEAEGCWFGRWGVNYIYGTSGVLCALALINPQKYQRHIQQGATWLVGCQNPDGGWGETC
FSYNDPSLKGQGDSTPSQTAWALIGLIAAGEATGNFAHDVIERGINHLVSTQQPDGSWFE
AYFTGTGFPCHFYLKYHYYQQYFPLIALGRYQAINPL
>A0A7K2ZA44|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID2119|TrEMBL
MTATTDGSTGAANLSAAPAGHPADTTTAADDVLAAARQAAERSVAHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPGDLSATIEAY
VALRLAGDRPEEPHMARASAWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPAEPNPARKLAPAASW
DGLFQRLDKGLHLYHKVAPRLLRRIAMNVAARWIVERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMVEACQSPVWDTCLATIALVDGGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARLEAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLGGHPRTRRGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALVAAGLPAAHP
SIRRAVTWLESVQNDDGGWGEDLRSYTEEKWIGHGESTASQTAWALLALLAAGRRDSRAV
ARGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRA
GVAKGA
>A0A380TEC0|squalene-hopene cyclase|EC 5.4.99.17|metagenome|TrEMBL
MRWSAAAVAQVEVEAARTESVLDRTIDDGLAWMFDRQASDGHWVFELEADASMPADYIML
SHYLGDIDEPLERKIATYLRRRQGAHGGWSMYYGGEFDLSLSVRAYFALKIMGDDPEALH
MRRAREAILAQGGAAKVNVFTRYALALFEQIPWRGVPWMPAETMLLPKWAPFHLDKVSYW
SRTVMVPLLVVSAFKPRARNLRKVNIRELFTTPPERHRGYQTNPTGSRIGNGLLVLDAVA
RLAEPFVPRPLQKLAIDKAMRFIEERLNGDEGLGGIYPAMMYSLIAMDALGYPRDHPSRL
MTRTAINKLLVVHPDEAYCQPCVSPVWDTALMLHALLETGMPGDDDAVASACDWLCARQI
LDVEGDWAVNRAGVRPGGWAFQYRNDHYPDVDDTAVVAMALNRADPDRYRHAVDRAAEWI
IGMQSANGGWGAFDADNQHEFLNNIPFADHGALLDPPTADVTARCIGLLAQLGYPATHPA
IARALAFLQREQEADGSWFGRWGTNYIYGTWSVLAALNAVGEDMTAPYIQRAVAWLKARQ
RDDGGWGEDCATYWPNQRDGAKASTPSQTAWALLGLMAAGEVDSDSVERGIGHLMAAPRE
GGKWDETYYNAVGFPRVFFLSYHGYSAYFPLWALARFRALKGGNSRRPAYGL
>T2AY46|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLAMHAVLEANSEPDKIIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWFGRWG
>T2AZX3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
VWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQYWN
DYYPDVDDTAVVVMALHRADPARYSEAIVRGAEWIIGMQSRNGGWGAFDVDNEHHFLQHI
PFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWFGRWG
>T2AZW5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLETNSVPDKIIIEKAANWLVERQILDVIGDWAANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDRYSEAIARGAEWIIGMRSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARSIVYLKRGQEVNGSWYGRWG
>T2AZ37|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYNEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGRWG
>T2AXZ8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMRSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGRWG
>T2AXX8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSMSDKTIMEKAANWLVERQILDVIGDWGVNAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVVRATGYLKRGQEVNGSWYGRWG
>T2AZE7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGLAMHALLEANLALDKAIMQKAADWLVERQILDVIGDWGANARGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRVDPNRYSEATERGAEWIIGMQSGNGGWGAFDKDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMLAQLGYGYEIEAVSRVVGYLKREQEHDGSWYGRWG
>T2AZA2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAICSNALLDSGLPTDHPALVRAGKWIVSKQVTKRGDWQVKNPKAEPGGWAFEFY
NELYPDTDDTAEILLFLNRVEIPDNRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGKWGFNKQHPQVKRAIKFVKERQEVDGCWYGR
WG
>T2AZV7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLATHAMLEANLSSGPRILENDSTSKACKWLEKLQIKDCAGDWAVWRPNLRPGG
WAFQYHNDYYPDIDDTAVVAMALHKTGNKIYEPALLRAAEWIIGMQSKNGGWAAFDADNE
YHLLDNMPFAEHGALLDPPSVDVSARCISFLTQLGYDQTNGTIKRGIEYLKKNQEEDGSW
FGRWG
>T2AZT9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGIACNALMDAGLPKDHPALIKATEFFFRKQVVKRGDWQVKNPNAEPGGWAFEFY
NELYPDNDDTAEILMAIHSIEFPDLRYKLKESQRALSWLLSMQSKNGGWGAFDQDNDQEL
FNAIPFADHNAMLDPPTVDVTSRIIWLLGILGYSREHPQVKKAIVYIISDQENDGGWYGR
WG
>T2AXT0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGFNGLSLLESGLTLKDSSIQKACKWLEKKQILEIKGDWIVNNKNLLPGGWAFQY
ENDFYPDVDDTAVIVMFLDRAGYQNKKRLEIACNWIIGMQSKNGGWGAFDKDNTYHYLNN
IPFADHGALLDPPTADVSARCISMLSQINKKNYKKITQKGVKFLKNEQENDGSWFGRWG
>T2B0B1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLNGLSLLESGLTLNDNAIQKACKWLEKKQILEMKGDWIVNNKNLLPGGWSFQY
ENDFYPDVDDTAVVGMFLDRAGYQNKKRLERACNWIAGMQSKNGGWGSFDKDNTDHYLNN
IPFADHGALLDPPTADVSARCVSMLSQINKKNYKNEIQKGIKFLKDEQEEDGSWFGRWG
>T2AZN2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTLLSMFAITDCGARLSQSEPLQQALRWVLSKEVTTIGDWKVRAPDASPGGWAFER
ENVAFPDIDDTAVALIILAHLREENPNDTRFDGPIERATAWVLAMQSDNGGWGAFDKNND
RDLLTKIPFCDFGEALDPPSVDVTAHVLEAFGLLGYDRFHPAMQRALAYVLSEQETTGSW
YGSWG
>T2B0C2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTAIVLRGLAEIASPAVDSSNSLANAVDWLLAREVRFAGDWSRRVQAVPSGWCFEY
ANCYYPDVDDTAMVLIAFASWLKRHKACPDSQEKASEDSQGERIRHTRNAMRRGIQWLTA
MQNSDGGWGAFDRDNNHELLCKVPFADHNAMIDPSSPDLTGRVLEAYGSLGHGVGEPGVD
RAIEYLRETQEPDGSWFGRWG
>A0A375IQA3|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus taiwanensis|TrEMBL
MSINETALANAAPQVDAAQREPAGPAKAPATRLPAPALDHGIGRALDALLHQQRPDGHWV
YELEADATIPAEYVLMVHYLGEDPDLDLEARMARYLRRIQNPDGGWPLFHQGRSDVSASV
KAYFALKMAGDDPQSAPMQRARRAIHAMGGAEASNVFTRTLLALYGVLPWKAVPMMPVEI
MLLPRWFPFHLSKVSYWARTVIVPLLVLNSLRPQARNPRGVGINELFVGNCHTVGLPSRA
AHQHAGWYTVFRGLDALLRVAEPLFPRALRRRAIATAQRFVRERLNGEDGLGAIFPAMAN
SVMMFEVLGVPPDDPARALARRSLERLLVEHGDEAYCQPCLSPVWDTALATHALLETGEA
RAAQAAGRALDWLKPLQVLDLRGDWAVRRPLVRPGGWAFQYANAYYPDVDDTAVVAAAMD
RFMRAHHAPGRYGEAVARATEWIVGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDPP
TADVSARCLSMLCQTGATPGKSEPAARALRYLLAEQMPDGSWFGRWGTNYIYGTWSALCA
LNAAGLGPEAPELQRAVAWLARIQNADGGWGEDGSSYRLDYRGYEPAPSVASQTAWALLA
LMAAGAAQHPAVARGIDYLLRTQQAGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWALA
RYRNLQRGQGGQVSWGL
>A0A5P2XHK7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces spectabilis|TrEMBL
MTATTDGSTGAVTPRAASATDTSDTTPGAAGAPEAAKRAVERSTEFLLSRQDPQGWWKGD
LETNVTMDAEDLLLRQFLGIRDEPTTRAAALFIRGEQRDDGTWATFYGGPGELSATIEAY
VALRLAGDAPDEPHMARASAWIRERGGIAEARVFTRIWLALFGWWKWDDLPELPPELLYF
PKWFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHRDPAVPNPPKPLAAVASW
DGVFQRLDKALHVYHKIAPRALRKAAMNSAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVLKAGIESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHPQL
VQAADWMLGEQIVRPGDWSVRKPHLTPGGWAFEFHNDNYPDIDDTAEVVLALRRVAHPDR
RRMDSAIARGVHWNLGMQSRNGAWAAFDVDNTSPLPNKLPFCDFGEVIDPPSADVTAHVV
EMLAYEGKSHDPRTRRGIEWLLAEQEANGAWFGRWGVNYVYGTGSVLPALVAAGLPAAHA
AIRRAVAWLESVQNDDGGWGEDLRSYRDERWIGHGASTASQTAWALLALLAAGERDSKAV
ERGVTWLTESQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPSVGGP
GKGS
>B1FUL0|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia graminis (strain ATCC 700544 / DSM 17151 / LMG 18924 / NCIMB 13744 / C4D1M)|TrEMBL
MNDLSQAHVLGAAMPETAGEAQNAQAAANSAAAAAEASAVLAPSLDAAITRATDAILAAQ
KPDGHWVYELEADATIPAEYVLLVHYLGETPNVELEQKIARYLRRIQLPNGGWPLFTDGA
IDISASVKAYFALKMIGDPVDAEHMVRAREAILAHGGAETVNVFTRILLALFGVVSWRAV
PMMPVEITLLPMWFPFHLSKVSYWARTVIVPLLVLNAKRPLARNPRRVRIDELFRGAPVN
TGMPARAPHQHVGWFGFFRVVDTVLRAVDGLFPKATRERAVREAVAFVDQRLNGEDGLGA
IFPAMANSVMMYDVLGYPADHPNRAIARRSIEKLLVIKDDEAYCQPCLSPVWDTSLAAHA
LLETGDARAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYNNAYYPDVDDTA
VVAMAMHRSEALTHSGADREAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHG
ALLDPPTADVSGRCLSMLAQLGEFPQNSEPAQRALDYMLKEQEADGSWYGRWGLNYIYGT
WTALCSLNAAGLPHDDPRIRRAAQWLLSIQNEDGGWGEGGESYKLDYRGYERAPSTASQT
AWALMGLMAAGEVDHEAVARGIEYLQREQREHGLWDETRFTATGFPRVFYLRYHGYRKFF
PLWALARYRHLKRNGLTRVAVGM
>A0A7Z8MIF8|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia thailandensis|TrEMBL
MNDMTEMHTLDATAAPAAPTVATGLDAAVARATDALLAAQNADGHWVYELEADSTIPAEY
VLLVHYLGEEPNVELERKIARYLRRIQLPDGGWPLFTDGAPNISASVKAYFALKVIGDDE
NAEHMQRARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSK
VSYWARTVIVPLLVLNAKRPVAKNPRGVRIDELFKSAPVNTGLLPKQPHQSAGWFAFFRA
VDGVLRLTDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPED
HPNRAIARQSIEKLLVVGEDEAYCQPCLSPVWDTSLAAHALLETGDERAREAAVRGLDWL
VPRQILDVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRE
SIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQ
FGETSASSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVK
RAAQWLLSIQNPDGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDNPAVAR
GIDHLLGTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVT
VGM
>A0A3L7Q1D6|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MDPRLQDQTVATLERPAPATQAPASAHTASEAAQAARRAADALFTLQRHDGHWCAELEGD
SILESEYMLMKFILGQEREPMADGRDGWQVMQELATSLREQQRADGGWGQYPGSAADVSS
CVKAWVCLRLMGDDERAPHMQRAAAMILARGGAESCNSFTNFYLAALGLIPWMAVPAIPP
EVVWLPRWFPFHLSKVSAWSRTMILPLAIVATLRPTRRVRLSLESITRDLGARRRLMMRR
EVPAGWRAFFRAIDLGLKGVGALIGTKPRRPAIRDAFDWIMQRASQDGPARTEGVGAIFP
PMVYLQIVFKALGIPRNDPRVQVAERDLDAFFLRDARGTRLQPCFSPVWDTGIGLYALTD
AGFDANDPRVAKACTWLESQEVTHVGDWAVHCAPGTGAGGWCFEYANAWYPDCDDTAMVA
MALHRARRGSSGAGDRGVRWMLAMQNDDGGWAAFDRTEHRQWMEYVPFADHNAMQDPSCP
DITGRVLECLSWHGLRCGDAAVDRAIRYIQSHQLPQGCFFGRWGVNYIYGTWQAVIGPIR
CGEPREAEWIRRAGAWMKSVQKPDGSFGESADTYEDPSLMGTGPSTASQTAWGAMVLQEI
YGADDPDLARAIAWLARTQLTPEQAADPAANPDGDPAGSWCETEFTGTGFPKVFYLRYHL
YRLYFPLMALGRYARAHGAA
>A0A6G3SXA0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces anulatus|TrEMBL
MTATTDGSTGTANPSGATAHDPTDTTIAADDVTVAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPGDLSATIEAY
VALRLAGDRPDEPHMARASGWIREQGGIAAARVFTRIWLALFGWWRWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPDHPNPPRKLAPPASW
DGIFQRLDKGLHLYHKVAPRPLRRIAMNLAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMKAGLASLDRFAVRREDGARMVEACQSPVWDTCLATIALADAGLRPDHPAL
VKAADWMLAEEITRPGDWAVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARLQAAIDRGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLAHHPRTREGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALIAAGLPAGHP
AIRRAVAWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAADRRDTRPV
ARGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRA
DTAEGD
>A0A6B0XL00|squalene-hopene cyclase|EC 5.4.99.17|Holophagales bacterium|TrEMBL
MIDAAVRNLLGQRRDDGHWCAELEGDTILESEYVLLLHFLGRADDPRVAACCERLRGQQQ
QGGGWAIYPDGPTDPSVSVKAYLCLKLAGDDPQSPRMADARRAILRAGGLGACNSYTRLY
LSIFGLWTWRRSPAVPPELILLPRWFYFNLHEMSSWTRTIVVPLSVIWALRPSVPLDVTL
DELQVDSPPRRRGTTLYESFWSRVFAGVNGLIKLVEVIGPVPGWRRPALKKAEEWLVAHV
EGSDGLGAIFPAMVNAVIAFRCLGYEESHPLVQGQLRELERFEIEEAGEMRLQPCLSPVW
DTALSVGALLAADMDGNDAPIREAVEWLLEREVTVAGDWREKSLQDASGGWCFEYRNDHY
PDCDDTAEVLLVLAAVRDRAGELEARKQAAAARGKRWLLGLQNPDGGWASFDRCCDKEVL
TLIPFADHNAMIDPSTPDITARVISALLAHGHDPGDGPVRRATDYLLREQEKDGSWPGRW
GANGIYGTWLALSALAPLAARPGGRAGERLSRACRLGRRWLLAVQNEDGGWGESLRSYDD
PAFRGRGRSTASQTAWAMMGLIASLESRPWSDDAARTVTALDRAVAFLQERQRDDGSWYD
RDWTGVGFPGVFYLRYHGYAQYFPLEALAAYRRLAVPEPDAMPANGPF
>A0A095QLX8|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia pseudomallei|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>T2AYL8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIFMEKAANWLVKRQILDVIGDWGANVHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDCYSEAIARGAEWIIGMQSGNGGWGAFDVNNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGLDNQAVARAIGYLKRGQEVNGSWFGRWG
>A0A6P1AID7|squalene-hopene cyclase|EC 5.4.99.17|Kamptonema sp. SIO1D9|TrEMBL
MQIDERKAIASVKEAYRKVGVAIARHQDYLLSKQNPQGYWWAELESNATITAEIVLLHKI
WGTDKSRPLHKVETYLRQQQREHGGWELYYGDGGEISTSVEAYMALKLLGVTETDPAMVK
AREFILAHGGISKTRIFTKMHLALIGCYDWRGLPAIPPWIMLLPDSFPIYEMSSWARGST
VPLLIVFDRQPVYQVDPAINLDELYAEGVENVRYELPRNDDWTDIFVFLDDAFKFAQDYN
LVPFREEGIKAAEKWVLERQEATGDWGGIIPAMVNSLLGLKALDYDREDPIIVRGMEAVD
RFAIEDEDSYRVQPCISPVWDTALVVRSLVDSGLSPDHPSLIKAGEWLLSKQILDFGDWA
VKNKQGMPGGWAFEFDNRFYPDVDDSAVVVMALNQVKLPNEKLKQEAIARTVAWIATMQC
YPGGWAAFDIDNDAEWLNLLPYSDLKATIDPNTADVTARVLEMVGNLNQNGDSPIISPKQ
LQRALDYLTQEQESEGCWFGRWGVNYIYGTSGVLVALSLVADYTHQDSIAKGAAWLVSCQ
NQDGGWGETCRSYDDPSLKGIGDSTASQTAWALIGLLAAGEATRNWATAAIERGVEYLLA
TQQADGSWNEDYFTGTGFPSHFYLKYHLYQQHFPLTALGRYARSVHLGQLS
>A0A5C0A8L5|squalene-hopene cyclase|EC 5.4.99.17|Gluconobacter thailandicus|TrEMBL
MLIYPDEKEDRVSEALSRKPIEGNDVTRAIEGAHAALGKRQKDDGHWVFELEADATIPAE
YVLLEHYLDRIDQNKQDKIGVYLRRIQGEHGGWPLYFGGGFDLSATVKAYFALKAIGDSI
DAPHMRRAREAILDHGGAARSNVFTRIQLALFGEVPWDATPVMPVELMLLPRTAFFSVWN
MSYWSRAVLAPMLAVGALKPQAINPRDIHIQELFVKPPAEVKDWIRGPYRSIWGRAFKHL
DTALRPVLPLIPKKIHDKALKAAISFIEPRLSRGGLGAIYPAMANVVMLYRALGVPDSDP
RVVTAWQSIQDLLVHKEDEIYCQPCVSPVWDTGLSGLAMMEAASGAHPTKRDETLAKLKK
SAEWLRDRQILDVKGDWAVNTPDLRPGGWAFQYENDYYPDVDDTAVVGMLLHRVDPEENH
EAIERAREWIIGMQSTNGGWGAFDVDNDLEMLNHIPFSDHGALLDPPTADVSARCISFLC
QLGHPEDRPVIDKALDYLRKEQEKEGCWFGRWGTNYIYGTWSVLCALNIAGISYDDPMVK
RAVNWLEDIQRSDGGWGEDCATYEGAPPGIYKESLPSQTAWAVLALMAVGRRNSEAVKRG
INFLMSRQDESGEWQEEAYNAVGFPKVFYLRYHGYKQFFPLQALSRYRNLGTSNTGRVEY
GF
>A0A7U6BXJ6|squalene-hopene cyclase|EC 5.4.99.17|Peribacillus butanolivorans|TrEMBL
MCLGGGTPLNHQHVQLEINRLVYHLKQDQTADGSWNYPFDTGITTDAYMIILLKILDIED
APLIEALVKRIESRQTENGSWKLFHDEKEGNLSVTIEAYYGLLYSGLRKKQDPHMRKAKQ
FILSNGGIKQTNTLTKMMLTVTGQYKWPPLFPIPLEVILLPPTFFINIYDLSVYGRVNLI
PLLLLGHKKYQIKSSNAPSLKDLYQTREELTEEYVWEEYRTDEYRSFFSKLQTGVKTLIG
YPDYLHSLALESTKRYMLDRLEPDGTLYNYFVSTFFMIFALLSTGYSKKDPVILKAVAGL
KGMACSVDGYTHIQFTTAHVWNTSLISYALQEAGLPSKDQTVKAANQYLLSRQHYMYGDW
LVHNPNAVPGGWGFSDLNTMNPDVDDTTASLRALAGQLQTNPDNQNSWQRGVAFTISMQN
DDGGFPAFERNNDHKWLHLTPFEGAKYFLTDPSTADLTGRTLEFLGNYTNLKKPEKVSKK
AVDWLLKDQERDGSWYGRWGICYLYGTWSALTGLKAAGQSSEHPAIQKALAWLKKVQNKD
GGWGESCYSDIKQHYMPLGISTLTHTAWAVDALISASEKPTPEIEKGITYLIRDAQKESW
TNDYPAGQALANLSYIHYHSYRYIYPLLALSHYRNKFMNV
>A0A4R5LAR8|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia guartelaensis|TrEMBL
MNDLSQAMRGVATPDVAMSAPTFADEMAAPVAAPLAALDAAVARATDTILADQRADGHWV
YELEADATIPAEYVLLVHYLGETANLELEQKIARYLRRIQLPEGGWPLFTDGAMDVSATV
KAYFALKMIGDAEDAEHMVRAREAILAAGGAEQVNVFTRILLALFGVITWYAVPMMPVEI
TLLPQWFPFHLSKVSYWARTVIVPLLVLGAKRPVARNPRGVRIDELFRGAPVSVGLNARS
PHQSKGWFGFFRAVDGVLRVTDPLFPTYLRQRAIDAAVAFVDERLNGEDGLGAIFPAMAN
AVMMYDVLGYPADHPHRAIARQSLEKLVTVHTEEAYVQPCLSPVWDTSLAAHALLETGDA
RAEEAARRGLEWLRPLQILDVRGDWISRREAVRPGGWAFQYANPHYPDVDDTAVVVAAMD
RVDKLDNTNAFDAPIARAREWVVGMQSSNGGWGAFEPENTQYYLNNIPFSDHGALLDPPT
ADVSGRCLSMLAQLGELPAASEHARRAYNYLLEEQETDGSWYGRWGMNYIYGTWTALCAL
NAAGLGHDDPRMKRAVQWLVQIQNDDGGWGEDGTSYKLEYRGYERATSTASQTAWALLGL
MAAGAVDHPAVARGIEYLQKTQQEHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALAR
YRNLKRAGVTRVTVGL
>A0A525WA37|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp. CG24D|TrEMBL
MKLFRTLFDRISSSLLATIPGKYNPAVGYAQTPPLRLVSDKVAPLAATDSSRRPSAHTVS
QPDAIDDAIRRSQSWFLSKQDPAEGFWVAELEADTTLTSEYLMLRRFLDCVDPVKEERAI
RYLRTMQLPDGGWPIYYGGPAEISASVKAYFALKLSGIPASDPCLLRARERIMAMGGVVQ
ANVFTKIALALFDQYDWEGVPHMPVEIMLLPKRFYFSIYAISYWSRAVLIPLLIVFAHQP
VCRIPREQGIEELYLVPRGQVPYWKYPPFNKDQAWFTPHNFFVMLDAVLKLYDRMPLLWL
REKAMHKAATWMLDHLKGNGGLGAIYPAMANSVLALRCLGYEMDDPLVQKALREIEDLEV
HETATVDGQRVPTLHLQPCHSPIWDTALLMNALIEAGMQQDHPALVKAGAYLMSRQTKTV
GDWTISSPQAEPGGWYFQFENELYPDVDDSAVVLMALAKLKMPEPADLRESIRRGMQWVL
AMQSSDGGWGAYDKDNNRVVFNYIPFADHKALLDPSTADLAGRCLEMLGALGYDRSHPAV
KPALAFLKKQQEADGSWYGRWGVNYIYGTWSVLAGLRAIGEDVSSPYIRRAVSWLESKQN
PDGGWGEVCLSYAEDAHSGKGQSTPSQTSWALMALMSAGVTESLSIARGVQYLLRHQLKD
GSWEEVMHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRSRGRMRAEELREQVESSGCY
RFDH
>A0A538K9I6|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MQLGETEPAVPPVTDARPGITPARNAEGALARARDHLLALQKPDGHWRGLLETNVTMDAE
DLLLREFLGITDRERSRRAASWIRSKQGSDGSWANFAGGPGDLSTTIEAYWALRVAGDEP
SAPHMQRAAAWSREHGGPRQARVFTHIWMALFGLWPWDEVPAVPPELMFLPRWFPLNPYD
FSCWARQTIVALMIVRAHRPSRQLAFTLEELGPSDPAAVAPAPSLAGRMLNVLDRVMRVY
ERHPLRPLRRAALTAAERWVVKRQEADGGWGGIQPPWVYSLMALHLQGYSLEHPVIRAGL
AGLDGFTVEDGDAMWLEACQSPVWDTALAILALADAGLKSDDPALVRGADWLLDRQELEV
AGDWAVRRRHLRPGGWAFEYHNVNYPDVDDTPICALALRRVEHPDPNQIERAVQRAVEWI
IGMQSGDGGWGAFDADNTRTIVRQLPFCDFGEVIDPPSADVTAHAVELLVQEESAAGRDS
ADRGLRWLWDEQESTGSWFGRWGVNHIYGTWSVLCALKEAHVPPDDGRLRRAVRWLELHQ
NPDGGWGEDCRSYEDPAWIGRGESTASQTAWALLGLHAAGAAGADSVRRGIDWLVATQRD
DGTWDEPQYTGTGFPGDFYINYHLYRLVFPVMALGRCLEALR
>A0A7W1JIC2|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MRRGRAAARPALQAGPRRGRDRRGRGARRGLRRAALRGGRGGAAHAARPARAGASSDRAG
RARGARRARPLHRGTRILTATAEPAVQATLGRAVDHLLSLQSPEGWWKGELETNVTMDAE
DLLLRQFLGIRTDEQTQQSAAWIRSKQREDGTWGNFYGAPADLSTTTESYAALKLAGDPS
DAAHMARAREYILDAGGLERTRVFTKIWFSLFGLWSWDDVPVMPPELMLLPPSVPLNIYD
FACWARQTVAALTVVSAYKPIRPVRFRLDELRTGIEPEPFAPLPTWPGAFQRLDRLLHLY
ERRPSSALRRAALKKAERWIVERQEADGSWGGIQPPWVYSLMALNLLGYPVEHPVMQKGL
EGLDKFTIVEDGIRRLEACQSPVWDTALALVGLGDAGLPPDHPAVEGGARWLLDEEVRVK
GDWAVRRPTLPPGGWAFEFENDWYPDIDDTAEVVMGLRRASLPGLDDAVARGVAWTIGME
SKDGGWGAFDADNVQELIRKLPFCDFGEVIDPPSADVTAHVVEMLAGEGMADHPSAQRGI
EWLLREQEPEGSWFGRWGCNYVYGTGAAVPALIDAGIAPEHESIRRAVRWLEQVQNDDGG
WGEDMRSYNDPEAWSGRGDSTASQTAWALLALHAAEEREGAAERGLAWLAETQREDGTWD
EPWYTGTGFPGDFYINYHLYRLVFPVIALARFAR
>A0A538CQY4|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
IRDAETTDRSARWIRANQRDDGSWANFRGGPGDVSTTVEAYVALRLAGDAPDAAHMAAAS
AFVRRAGGLENARVFTHLWLALFGAWPWECVPAVPAEVVLLPAWFPLNVYDFACWARQTI
AALAVVMAYRPRRPLPFDLGELHGTREPATRRARTWRGLALTLLDRVVHRYERRPIRRLR
DIALDRAERWIVDRQEADGSWGGIQPPWVYSMIALHLRGYGFDHPVMQRGFEGLDRFTID
DASGRRLEACQSPVWDTALSLIALADAGLERNDAAIVRGADWLLEQQVLGRGDWSVRRPD
LAPGGWAFEFANANYPDVDDTAEVVLALRAVDHPDPARVQRAIDRGVAWVEGMQSADDGW
GAFDADNCRALVRDLPFCDFGEVIDPPSADVTAHAVEMLAAVGRPTRGGAEWLLAAQEAD
GSWFGRWGVNHLYGTGAAVPALVAAGIDPSGERIRRAVRWLEDHQNADGGWGEDCRSYDD
PAWIGRGASTASQTAWALLALRAAGEDSLAVRRGVRWLVDTQRPDGTWDEPQFTGTGFPG
HFYINYHLYRLVFPLMALGRCAR
>A0A6P1BVZ8|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium uaiense|TrEMBL
MLSRDHGVTVDPVALEKSISKATEALLGYRQSDGHWVFELEADSTIPAEYILLRHYLAEP
VDAGLEAKIGNYLRRVQGAHGGWPLVHDGPFDMSASVKSYFALKMIGDSVDAPHMVRARE
AIRSRGGASASNVFTRFLLALYGVVTWRATPVLPIEIMLLPMWSPFHINKISYWARTTMV
PLMVLAALKPRAKNPKGVGIDELFLEDPKSLRMAPKAPHQSASWFYLFRSLDAVLRVIEP
VFPKSLRQRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYEALGKDENFPPRAITRRG
IDKLLVIGDDEAYCQPCVSPVWDTALTCHALQEVGGDDALAKAKQGLDWLKPRQVLELKG
DWAVKAPDVRPGGWAFQYNNDHYPDLDDTAVVVMAMDRVRRHTGTREYDEAIARGREWIE
GLQSRDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLGQLGETTESSKA
MADGVAYLRRTQLAEGSWYGRWGLNYVYGTWSVLNALNVAGVDRNDPMVRKAVDWLASVQ
NQDGGWGENAVSYRLDYKGYEVAPSTSSQTAWALLGLMAAGEVENPAVVRGVEYLKATQT
EKGLWDEHRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNSRVVGVGM
>A0A4R1B147|squalene-hopene cyclase|EC 5.4.99.17|Cytobacillus praedii|TrEMBL
MKSRISAGINQLIEKLKKDQSPTGSWDYPFETGISTDCYMIILLRTLEIHDENLIIQLTE
RIISKQEKNGAWKLYYDEGEGNITATIEAYYALLYSGYYSKKDPLIKKARQYIVANGGLD
SAHLLAKLMLAMTGQLKWPARFPLPLELILLPPTFPINFYSFSVFGRANMAPIMILANRK
YQIRLENSPDLSDLYTRKMDYNRDSFHFNNTEDWRSLCATIEKGIKSLMGMPSYIHKLAT
EQTKQYMLARIEPDGTFLGYFSSTFLMIFALLSLGYSKKDPIIIRAVKGLKSMQCEINGL
IHIQYTNASVWNTSLISYALQEAGVSPKHQMADRANNYLISQQHYKYGDWIIHNPSSSPG
GWGFANNNTLHPDVDDTTASLRAITRNVLSTPAYRQSWERGVLWTLSMQNNDGGWPAFER
NTNSNLVGILPIDKADFLLTDPSSADLTGRTLEFLCSYTNLSKNHKAIKEGMNWLLHNQE
RDGSWYGRWGICYIYGTWAAVTGLRSAAVRENHHSIKAASNWLCSIQNPDGGWGESCKSD
SKQVYVPLKSSTLTHTAWAVDALIAVSNKPTKAINAGINFLLNQLHQKDWTTDYPEGQGM
AGDFYIHYHSYRFIFPLLAFAHYQNKYLTH
>A0A6I5B3X5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4941|TrEMBL
MTATTDGSTGAANLRAVTFGDPIEPTTDTDDVLAAARRAAGRSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETVQAAARFIRGEQLGDGTWNTFHGGPPDISATIEAY
VALRLAGDLPDDPHMLRAAGWVREQGGIAASRVFTRIWLALFGWWKWEDLPELPPELMFF
PSWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPEHPAPPRPLAPAASW
DGVFQRLDKALHAYHKVAPRRLRRIAMNAAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLEHPVMRAGIASLDRFTVWREDGSRMVEACQSPVWDTCLATIALADAGVPPDHPAL
VRAADWMLGEEIVRPGDWSVRRPQLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDQ
PLVDAAIERGVRWNLGMQSRDGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLATDPRTRRGIQWLLDEQEASGAWFGRWGVNYIYGTGSVVPALIAAGLPASHS
SVRRAVSWLESVQNDDGGWGEDLRSYREEKWIGHGASTASQTAWALLALLAAGERESRVV
ERGVTWLAETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFAAAG
TGTAAGKEA
>A0A4P7D5K5|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia pallida|TrEMBL
MKNSDLPTNVQQAALLDAAIVRGRDALARRQQPDGSWCFELESDATITAEYILMMHFMGK
IDTVRQEKMARYLRAIQRLETHGAWDLYVDGAADVSASVKAYFALKAAGDAQSAPHMVRA
REAILKLGGAAKSNVFTRILLATFGQVPWRATPFLPIEFVLFPKWVPISMYKVAYWARTT
MVPLLALCSLKAQARNPHNVSIAELFVTPAEEEREYFPRGKGVRKLFLALDRAVRHLEPL
IPRALRARAMKHAEAWCAERMNGEDGMGGIFPPIVYSYQMMEVLGYHENHPLRRDCENAL
EKLLVERPDGSMYCQPCLSPVWDTAWSTMALEQAVAVPDQSGVATSGVDASGVATSGVAS
TPIAELQQKIARAYDWLATRQVDDLKGDWIENVSPDVPPGGWAFQYANPYYPDIDDSAVV
AAMLHRRGRSIQRATGTDPYAARVTLALDWMRGLQSRNGGFAAFDADCDRLYLNAIPFAD
HGALLDPPTEDVSGRVLLCLGVTGRAEDKAALARTIDYIKATQQADGSWWGRWGTNYIYG
TWSVLAGLALAGEDPSQPYIARALAWLRSRQHADGGWGETNDSYVDPRLAGTNGGESTSN
FTAWALLAQMAFGDHESESVRRGIAYLLSVQDSEGFWWHRSHNAPGFPRIYYLKYHGYTA
YFPLWALARYRRLAADGARVSAVKADEAVMLA
>A0A4P7CXV3|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia pallida|TrEMBL
MNDLSEAMPADDLANALGAAPTLDNASALLRAAAPADVSDALDAAVMRATDAILADQRAD
GHWVYELEADATIPAEYVLLVHYLGEEANLELEGKIARYLRRIQLPGGGWPLFTDGAMDV
SASIKAYFALKMIGDAEDAEHMVRAREAILAAGGAEKANVFTRILLALYGVVSWYAAPMM
PVEIMLLPKWFPFHLSKVSYWARTVIVPLLVLGARRPVAKNPRGVRIDELFRGAPVTVGL
NERSPHQSKGWFGFFRAVDGVLRITDPLFPAYLRQRAIDAAVAFVDERLNGEDGLGAIFP
AMANAVMMYEVLGYPADHPHRAIARQSLEKLVTVHAEEAYVQPCLSPVWDTSLAAHALIE
TGDARAHEAARRGLDWLRPLQILDVRGDWISRRPDVRSGGWAFQYANPHYPDVDDTAVVV
AAMRRVDQIDNTSDYDEPIARAREWVVGMQSSNGGWGAFEPENTHEYLNSIPFSDHGALL
DPPTADVSGRCLSMLAQLDELPVASEPARRAYNYILAEQEADGSWYGRWGMNYIYGTWTA
LSALNAAGLEHADSRMKRAAQWLIAIQNDDGGWGEDGTSYKLEYRGYERAASTASQTAWA
LLGLMAAGEVNHPAVARGVAWLQATQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLW
ALARYRNLKRDGITHVRVGL
>A0A6I5H6R9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID89|TrEMBL
MTATTDGSTGATLPTRAAAASEPVLTTPVAAGVHQAAEHAVRRATDFLLSRQDAEGWWKG
DLETNVTMDAEDLLLRQFLGIQDEATTHAAALFIRGEQREDGTWATFYGGPGELSTTIEA
YVALRLAGDAPDAPHMAKAAAWVRARGGIAASRVFTRIWLALFGWWKWEDLPELPPELIY
FPTWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAQPNPVKPLAPAAS
WDGAFQRLDKALHAFRKVAPKRLRRSAMNTAARWIIERQENDGCWGGIQPPAVYSIIALH
LLGYDLQHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQ
LVKAADWMLGEEIVRPGDWSVRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHD
PERVDRAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGLAHDPRTRRGVQWLLEEQEPDGSWFGRWGVNYIYGTGSVVPALTAAGLPGSH
PAIRRAVAWLKRVQNDDGGWGEDLRSYRDSKKWSGKGASTASQTAWALMALLAAGERDSE
AVERGVRWLADTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFAA
QAPAGRLLAEAKGS
>A0A6G2YZF1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8373|TrEMBL
MTATTDGSTGAVDPRAASASRPTIESTIAADGVPAAARRAAERSVEHLLGRQDEQGWWKG
DLATNVTMDAEDLLLRQFLGIQDPATLRAAAGFIRGEQLGDGTWATFHGGPADLSTTIEA
YVALRLAGDRPEDPHMARAAGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMF
FPPWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPDRPNPPKRPAPAAS
WDGLFQRLDKALHVYHRFAPRGLRRVAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVMRAGLESLDRFAVWREDGTRMIEACQSPVWDTCLATIALADAGLAPDHPA
LVKAADWMLAEEIVRPGDWAVRRPRLEPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPD
QARVDAAIERGVRWTVGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHV
VEMLAIEGRAADPVTRRGIEWLLSEQDPAGGWFGRWGVNYVYGTGSVVPALVAAGLPPAH
PSIRRAVEWLESVQNDDGGWGEDLRSYSEEKWIGQGASTASQTAWALLALLAAGRRDTVA
VTRGIAWLTETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFADR
TPMREGA
>A0A6B3A7R3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8014|TrEMBL
MTATTNGPAGAAPSRPAPARPTTDTTTAPDSATVEAAAERARARAADHLLGLQSPEGWWK
GDLDTNVTMDAEDLLLRQFLGIRDEATTRAAALFIRGEQREDGTWATFHGGPPDLSTTVE
AYVALRLAGDSPDAPHMTRAAHFVRARGGIAEARVFTRIWLALFGWWPWDRLPELPPELI
FLPPWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPANPAPRTRLAPLA
SWNGAFQRLDRALHTYRKVAPRALRRAAMAAAGRWIIERQENDGCWGGIQPPAVYSMIAL
HLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALADAGVPADHP
QLVRAADWMLDEQIERPGDWSVRRPHLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHP
DTARLERAISLGVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDPPSADVTAH
VVEMLAAEGLAADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALIDAGLPAT
HPAIRRAVAWLESVQNDDGGWGEDLRSYRDQGRMARGASTASQTGWALMALLAAGERESA
AARRGVAFLADTQHEDGSWDEPYYTGTGFPWDFSINYHLYRQVFPLTALGRYTRGAAPEA
A
>A0A5R9DYF1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces marianii|TrEMBL
MTATTDGSGGAPAFRAPSASDRTTDHRPAPEDPGNLGTTALLAAQRSVEHLLGRQDTQGW
WKADLETNVTMDAEDLLLRQFLGIRDEKTTAAAAVFIRGEQRADGTWATFYGGPGELSTT
VEAYVALRLAGDGPDDPHMERAAAWVRAQGGIAASRVFTRIWLALFGWWKWEDLPQLPPE
LIYLPSWFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDRHDPSPPRPPAP
AASWDGVFQRLDRLLHRYHRVALRPLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSMI
ALHLLGYDLDHPVMRAGLESLDRFAVWRDETTGPGGRPEGPARMVEACQSPVWDTCLTVV
ALSDAGVPADHPALVRAADWMLGEQITRPGDWAVRRPRLAPGGWAFEFHNDNYPDVDDTV
EVVLALRRVKHPDPLRVDEAVARAGNWTLGMQSRNGAWGAFDADNTGTFPNRLPFCDFGE
VVDPPSADVTAHVVEMLAHEGRAHHPRTRRGVEWLLREQEPNGAWFGRWGVNHLYGTGAV
VPALTAAGVPGSHPAIRRAVGWLESVQNDDGGWGEDLRSYREESWIGRGVSTPSQTGWAL
LALLAAGERDGKAVGRGIAFLAAAQREDGSWDEPYFTGTGFPWDFSINYHIYRQVFPLMA
LGRYAHGEPPTGRNGG
>A0A6N8T2C4|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. 4701|TrEMBL
MNPIPFFSPSALDAAIVRGRDALAHLQQPDGSWCFELESDATITAEYILMMHFMDKIDDV
RQARMARYLRAIQRLGTHGAWDLYVDGAPDVSCSVKAYFALKAAGDSEHAPHMVRAREAI
LKLGGAARSNVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPVSMYKVAYWARTTMVPL
LVLCSLKARARNPRNVSIRELFVTPPDEERRYFPPATGMRKLFLAMDRIVRHVEPLLPKR
LRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMEVLGYPEDHPLRRDCENALEKLL
VTRADGSMYCQPCLSPVWDTAWSTMALEQARGASAATQDALVPDRELDAHIARAYNWLAT
RQVNDLEGDWRENARRGTQPGGWAFQYANPYYPDIDDSAVVTAMLDRRGRAQARVSGEDP
YAERVSRALDWMRGLQSRNGGFGAFDADCDRLYLNAIPFADHGALLDPPTEDVSGRVLLC
FGVTRREEDKTARARCIEYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALSGEDKSQPY
IVRALDWLRAQQHADGGWGETNDSYADPRLAGTNYGESTSNYTAWALLAQMAFGDWQSDS
VRRGIAYLLSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLAGAQPA
PPARDPGTANAVADQAVA
>A0A7Y6HAU6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. CAI 127|TrEMBL
MTATTDGSTGAANITGAPADDPTDTRTAANDVTDIARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPGDLSATIEAY
VALRLAGDRPDEPHMARASGWVRDQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPDHPNPPRKLAPPTSW
DGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMIEACQSPVWDTCLATIALADAGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARLEAAIARGVRWNLGMQSRNGAWGAFDADNTSAFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLAKHPRTREGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALITAGLPAGHP
AIRRAVDWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDTASV
TRGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFADRT
DAAEGV
>A0A534FJG8|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MSRKVGTSAALAGTEGLLRADAPARKLPGEKLSPLEYAIAAARDELIRLQRPDGSWELEL
EADCTIPAEYIMMMHFLGELDSALEAKLAEYLRQRQAGYGGWPLYHGGAFDMSCSVKVYF
ALKLAGDDPESPHMARARTAILERGGAAACNVFTRIALALFGQLPWRGVPYIPVEIVLLP
RWFPFNIHRVSYWSRTVMVPLLILCTLKPRAKNPRNVDIRELFTTPPSQERRYFRRPLGG
SAALARAFFCLDRFARSLDGLIPRALREHALERAEAWMLERLNGEDGLGAIFPAMVNALE
ALAVRGYSPDHPHRRGAKRALEKLLVEDYSSAYCRPCVSTVWDTALASLAMQEEGSAGAR
AAALRGLEWLEPRQLLDEPGDWRTRRPHLPGGGWAFQRANSYYPDLDDTAAVAWSMHRST
DPGRFSFALSRALDWLVGMQSENGGFASFDVDNTSYYLNEIPFADHGALLDPPTSDVTAR
VVTALARVGRPEDRGALTRAIDYLRREQEANGSWFGRWGTNYVYGTWSVLCAFAAAGIGR
DDPAVERAVRWLESRQNPDGGWGESNDSYEPGRAGASAPSTPHQSAWAVLALIAAREAGS
DAVRR
>A0A521R9F6|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MHDGTTVSEATRPTLVTDMLRIQHEIHAPAVISDPLARTVQHSADALLEMQAGEGFWRFD
LEADTTIPAEYLFLQYFLGSVDVTRQAKLADYILSRQLQDGSWPLYEGGPGNISASVKSY
FALKLAGKDPASPEMKLARQWVLTHGGAENANVFTRITLAVYGQIPWRTVPAMMAEVIWL
PKWFLLFNLHKVSYWSRCVIVPLLIIFATRPVHALTTNQGITELFVSNPGALKHLDRFNQ
GSLLKNLFILIDRMLKIAESFVPAGLRDMSVRKAEKWMREHMRGEGGIGAIFPAMANAVM
ALKILGHDATDPDMRRGIKAIEDLVIENENETFVQPCVSPIWDTCLSISALTEAGVSTNA
DPIQSATDWLFEKQVFVRGDWSENAPDLDEGGWAFQFENDLYPDVDDSSMVIMALLRADA
QANPDKRGRIAQGVNWVLGMQNPDGGWGAFDIDNHYEYLNNIPFADHGALVDPSTADLTG
RCIEMLAMLGYDRSFPPIARGLEFLRREQEPSGSWYGRWGVNYIYGTWAVLVGLGALGED
PSQPYIRKAINWLKSIQNRDGGWGESCDSYDDPDLQGRYESTASQTAWALLGLMAVGEVD
SECVTRGINFLMRTYEGKGGWKETPYTGTGFPKVFYLKYHGYSHYFPLWALGVYQRLKAG
KPTRQQEVCAGGPIELGPMPVVEKIRLRP
>A0A7W7DUU8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces luteogriseus|TrEMBL
MHVLNRVGTDGAVRDACRSRVLESALALALVERCGSGHHDARTRIVSYLERHQNSEDLID
ATVAAAALGRGTRQPARRQALEDIVSRVPDFTGSRKRALVQAIFTMLGVATDHADAAPHA
VDVSALHPWAAVQTVAVNAILGRAVGRNRAGGEDVTRLASTQRPGRVWEGNLFIHLSVLH
ALVDVPGMESVVDAGLSTALRHQREDGGLPFVTDTDTWSTVVVGLALGSAGAPREVMHRI
ARHLVHLQHANGGWSYTDHAELSDTDCTTVAVEFLHQLDPVAYRDPIERALDALVAVRGA
DGGFPTYGAGTPSEACMTAAAINALSTQDRHRHLIQPALRFLADRQMPDGSFPPGWSSSR
LHTLFRAYLATLHRQASLTVQDMSGRIAGLVQSTQNADGGFGQRDGASSDAISTAYALII
LAGQRDPAPAAHATGYLLTQQRPDGSISSVPDMLGPRPFPYHVPVLADAFTLLALCHLTP
RIRPPRIAVPGRQHSNAQLARRTAP
>A0A6N9VGN4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces microflavus|TrEMBL
MTATTDGSTGAANLSAPPAGHPADTTTAADEVLDAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGILDPETTRAAALFIRGEQLGDGTWNTFYGGPSDLSATIEAY
VALRLAGDRPDEPHMARAATWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPAHPNPPRKLAPAASW
DGIFQRLDKGLHLYHRLAPRPLRRIAMNVAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMVEACQSPVWDTCLATIALVDGGLRPDHPAL
VRAADWMLAEEITRPGDWSVRRPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVHHPDP
ARLEAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLGSHPRTRRGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALVAAGLPAAHP
SIRRAVTWLESVQNDDGGWGEDLRSYTEEKWIGHGESTASQTAWALLALLAAGRRDSRAV
ARGVTWLTGAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYAYGDPFADRT
GAAKGA
>T2JPB9|squalene-hopene cyclase|EC 5.4.99.17|Crocosphaera watsonii WH 0402|TrEMBL
MEYGDWAVKNKAGKPGGWAFEFTNRFYPDLDDSATVVMALNGIKLPDEARKQAAINRCLQ
WIETMQCKEGGWAAFDLNNDQAWLNEVPYGDLKAMIDPNTADVTARVVEMLGSCDLEIES
DRLNKSLNYLYKEQEKDGSWFGRWGVNYIYGTSGVLSALAVINPEKHKTQMEQGINWLLS
CQNKDGGWGETCRSYNDPSLKGKGVSTPSQTAWSLIGLLDAGEALNKFETDAIERGVNYL
LDTQTEEGTWEESEFTGTGFPCHFYIRYHFYRHYFPLIALGRYQNLSSEFGVRS
>A0A7G8BKA3|squalene-hopene cyclase|EC 5.4.99.17|Acidobacterium sp. 4Y35|TrEMBL
MSTSTGTAKRGTPRFGRIDAALESVEAAIKRSRDYIFSIQDSEGYWCGELEADAMLEADY
IFVHRFLGTGEEAKLRRALTEMLRFQNDDGSWSIYPGGPGNISLTVKCYFACKLMGWSAD
EPILAKAREWILAHGGVVRCNTFTKIYLCALGQYEYDAVPAVPPEIVLFPKWFYFNIYEI
SSWSRAILVPLSIAYAKKPFRKIPHEQGIDELFVGGRENANLHLKWDSKNKISWRNFFLM
WDRVAHWAERIHIRPLRSIALKKAEKWLLERFEMSDGLGAIYPAMLNAIVALRCLGYSLD
DPQVIRAIDEFEKLGIDEPNGSAACSEPTFRMQPCMSPVWDTAQAVYALGEAGVDRNDPR
MLKAADWMLSKEVRHKGDWAVKVRNTQPGGWYFEFNNEFYPDVDDTAQVLLALNKVDNPR
ERYQHDVCLRAIDWVFAMQCRNGGWASFDKDNTKMIFQHIPFADHNAMLDPPTVDITGRI
LEMLAIYGYTRKDKRVEKAIKFIYEEQEPDGSWFGRWGVNYLYGTFLVLRGLEAIGVWNH
EPQIQQAAEWIRMVQNSDGGWGESCGSYDDPTTRGVGVSTPSQTAWAILGLLAAGDIRSD
SVAKGVRWLIEHQQKDGNWDESVGKGGARQAIYTGTGFPRVFYLAYHEYRNYFPLLALTN
YKRAMERAA
>A0A6I1F282|squalene-hopene cyclase|EC 5.4.99.17|Bacillus sp. B1-b2|TrEMBL
MDDTVKLVRKELDSRITQLQKLQHTDGSFRFRFQGSLMTDAFFIITIRALDIHTEEPNVQ
ALAKSLRSTQHKEGYWKAYSDEPNGHLSATVIAYTALLYSGYYQKEDALMKKAASFIQKN
GGIAKAHFMIKWMLSVNGLYPWSHMIYIPMTFLLLPTFQPINFYQFSAYARIHFIPILIA
ANKKFSLNSQNRPNVDHLYSRNEELYPSYAQLENERSPISFLWKEMKRIGKFPSYLHHLG
FQYAEKYMLERLEEDGTLYSYASSTFFMIYALLALGYKKESPTIQNALTGLSGLIDKKGT
HAHLENSTSTVWDTALISYTLQQADLSPQNETVKKATTYLLSKQHTRLGDWHIHNPNTSP
GGWGFSHINTNNPDNDDTSATLRALTKSATISSTVQEAWQKGTNYLLSMQNKDGGWGAFE
KNTNWEILNYVPIENAKDAAIDPSTADLTGRVLEYLGNFANLKKDHPHIKQGVDWLLDHQ
EEDGSWYGRWGVCYIYGTWAAITGLIAVGVAKTHPAIQKALTWLKSIQLKDGGWGESCQS
CEKLIYIPLTFSTDSQTAWAIDALLAGGEWKSKQVEKGVNYLIAANKKDASIRYPTGIGL
PGQFYIYYHSYNKIFPLIALSHYVKKWSK
>A0A418VH16|squalene-hopene cyclase|EC 5.4.99.17|Rhodopseudomonas palustris|TrEMBL
MDSGIHNSGAERGRTLEASIDAARSALMGFRRDDGHWVFELEADATIPAEYVLMRHYLGE
PVATELEAKIAVYLRRTQGAHGGWALVHDGDFDMSASVKAYFALKMIGDDVDAPHMARAR
EAIRSRGGAIHSNVFTRFMLAMYGVTTWRAVPVLPVEIMLLPSWSPFTLTKISYWARTTI
VPLMVLSALKPLARNAKGVGIDELFLQDPKSIGLLAKSPHQNAFLFNLFGSIDGVLRAIE
PYMPKKYRKLSIEKALAFIEERLNGEDGLGAIFPPMANTVMMYDALGYGEDYPPRASQRR
GIELLLVDRGDEAYCQPCVSPIWDTALASHAMFEADRTEGAKTVQPALDWLLPRQVLDLK
GDWAAKAPDVRPGGWAFQYNNAHYPDLDDTAVVVMALDRARKDKPNPAYDTAIARAREWI
EGMQSDDGGWAAFDVNNTEYYLNNIPFSDHGALLDPPTEDVTARCVSMLAQLGETSATSP
ALARGVEYLRKTQLADGSWYGRWGLNYVYGTWSVLCALNAAGLDHQDPAIRKAVAWLESV
QNPDGGWGEDAISYRLDYRGYERSASTASQTAWALLALMAAGEVDHPAVARGVEYLKGTQ
TEKGLWDEARYTGTGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNSKVVGVGM
>A0A6G9Z6J5|squalene-hopene cyclase|EC 5.4.99.17|Nocardia terpenica|TrEMBL
MTATDPDLTTPSTAAAATDALGAAVGHLRALQHETGWWKGELATNVTMDAEDLLLREFLG
ISTPAVTEPAARWIRSQQRPDGTWATFHDGPGDLSTTVEAWVALRLAGDAADAPHLRAAA
EFVRASGGVENSRVFTRIWLALFGLWSWDDLPNLPPELVFLPSWFPLNIYDWGCWARQTV
VPLTVVATLRPSRPLPFGINELRSGAPRPKRQSILGLAGLFQRLDSVLHGYARYPVAPMR
NLAMRRAAEWILARQEADGGWGGIQPPWVYSLLALHLLGYPLDHPAIRAGIEGLDGFTVR
EHTPDGEVRRLEACQSPVWDTGLAVAALLDAGVPGDDPAVLRATDWLLGEQITGGGDWQV
RRPRLESGGWAFEFANDAYPDTDDTAEIVLALHRVSHPDPARLAAAVDRAAEWTVGMQSR
DGGWGAFDADNTSTLPMKLPFCDFGAVTDPPSADVTAHAVEMMAALGRGAEPACRRGVRW
LLDHQESDGSWFGRWGANYVYGTGAAVPALVAAGLNPRSTPIRAALAWLEEHQNPDGGWG
EDLRSYRDPAWIGRGASTASQTAWALLALLAADPDSPAVDRGIAWLLDTQRPDGTWDEDH
YTGTGFPGDFYINYHLYRLVFPIWALGRYTRARQRPTP
>A0A7W7QY04|squalene-hopene cyclase|EC 5.4.99.17|Kitasatospora kifunensis|TrEMBL
MTATADGRLDPEYDSEPVAVDERPSAALAHAADAGPWQVGEDGAEALGGLVAHAPVDRVA
IEDSLRRATAHLLSLQDAEGWWKGDLETNVTMDAEDLLLRQFLGIRTVEQTAATAEWIRS
QQRADGTWGTFHGGPPEISTTVEAYVALRLAGDQPDAPHMRAAAEYVRGAGGIAATRVFT
RIWLALFGWWPWERLPEMPPEIMFLPKWLPLNIYAFGCWARQTIVPLTVVSAHRPVRPGP
FELTELHTDPANPFPLRPLAPPASWDGLFERLDLVLHAYHKRAVRPLRRLALSQAGRWIV
ERQEADGCWGGIQPPAVYSLIALHLLGYELDHPVMQSGLAAFERFTVHTEDGKRWLEACQ
SPVWDTCLATIALVDAGLPADHPALVKASDWMLGEEITTKGDWSVQRPQLAPGGWAFEFH
NDTYPDIDDTAEVVLALRRVVHPEPERVAGAVYRGVEWNLGMQSKNGAWGAFDVDNTSTL
PNKLPFCDFGEVVDPPSADVTAHVVEMLAEVGKADDPRTRRGVEWLLRNQEAEGSWFGRW
GTNYIYGTGSVVPALVAAGVPESEPAIRRAVRWLEERQNPDGGWGEDMRSYEDPEKWSGR
GESTASQTAWALMALLSAGEGPGGRFAPGPDRGSAAVERGVRWLALTQLAEGSWDEPQFT
GTGFPWDFSINYHLYRLVFPVTALGRYLHGNPVLGHAGRSA
>A0A5R9G0X9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces montanus|TrEMBL
MTATTDGSTGALPPRAASASEIHTTTPAATGTADTRDAAARAIQRATDFLLSIQDPQGWW
KGDLETNVTMDAEDLLLRQFLGIRDEKTTHAAGLFIRGEQREDGTWATFYGGPGELSTTI
EAYVALRLAGDAPDEPHMEKAASWIRDQGGIAAARVFTRIWLALFGWWKWEDLPELPPEL
IYFPKWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDARDPNPAKPPAPV
ASWDGVFQRLDKALHAYRKVAPRRLRKAAMNTAARWIIERQENDGCWGGIQPPAVYSVIA
LHLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADH
PQLVKAADWMLGEEIRRPGDWAVRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKH
HDPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVTA
HVVEMLAVEGLSHDPRTRRGIEWLLAEQEGDGSWFGRWGVNYVYGTGSVVPALTAAGLPG
SHPAIRRAVAWLETVQNDDGGWGEDLRSYRDVAQWSGRGASTASQTAWALLALLAAGERE
SKAVERGITWLAETQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPF
ADRQATGSP
>A0A7T7I298|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. ZYC-3|TrEMBL
MTATTDGSTGALPPRAAAASETTEVTTPEAAGTVDTRDAAERAILRATDFLLSTQDAQGW
WKGDLETNVTMDAEDLLLRQFLGIRDEATTRAAGLFIRGEQREDGTWATFYGGPGELSTT
IEAYVALRLAGDAPDEPHMARASAWIRERGGIASARVFTRIWLALFGWWKWDDLPELPPE
LIYFPKWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDASNPNPVKPLAP
VGSWDGVFQRLDKALHTYRKVAPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSII
ALHLLGYDLEHPVMREGLASLDRFTVWREDGARMIEACQSPVWDTCLATIALADAGVPAD
HPQLVKAADWMLGEEIVRPGDWAVKRPHLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVK
HHDPERLDKAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVT
AHVVEMLAVEGLSHDPRTRRGIEWLLAEQEANGSWFGRWGVNYVYGTGSVVPALVAAGLP
GSHPAIRRAVAWLETVQNDDGGWGEDLRSYHDVAEWSGRGASTASQTGWALLALLAAGER
DSKAAERGVAWLAETQLADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEP
FADRQGSFGRAS
>A0A089P0I8|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium oryzae CBMB20|TrEMBL
MREAVSKVEALQRSKTQGIALEDVERGVAQATRALTDLAHDDGHICFELEADATIPSEYI
LFHHFRGTQVPGDLEAKIGTYLRRTQGRHGGWALVHEGPFDMSCTVKAYFALKMIGDDIE
APHMRRAREGILSRGGAANANVFTRFMLALYGEVPWRAVPVMPVEVMFLPKWFPFHLDKI
SYWARTTVVPLFVLQATKPRARNPRGISVQELFITPPESVRSWPGSPHATWPWTPIFGFI
DRVLQRVENHLPRKSRQRAMEMARAWVSERLNGEDGLGAIFPAMVNSVLMYEVMGYRPDH
PQVRVACDAIEKLVVEKADEAYVQPCVSPVWDTALASHALLEAGGPEAEAQARAGLDWLK
PRQVLDIVGDWAARKPKVRPGGWAFQYANAHYPDLDDTAVVVMAMDRAMRQHGLVAGMPD
YKVSIARAREWVEGLQSEDGGWAAFDADNNHMYLNHIPFSDHGALLDPPTADVTARVVGM
LAQLGETRETSRALDRGVNYLLNDQEEDGSWYGRWGMNFIYGTWSVLCALNAAGVDPADP
RIQRAVNWLIRIQNPDGGWGEDASSYKIDPAFEPGSSTASQTAWALLALMAAGAVDDPAV
TRGINFLTRTQGADGFWKEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKRGNSRR
VQFGM
>A0A7Y3K7S1|squalene-hopene cyclase|EC 5.4.99.17|Phycisphaerae bacterium|TrEMBL
MNESAGFRNQFLSQIEPLASATEAISSAADHDISESMPDFATRSLASPETHSLDESLLAA
VNCLLGQHKPQGYWVGELQGDSILESEYILMKFILEEENDPDLPLIANYLRRLQQADGGW
NMFPGGNSDLSGTVKAYFALKLMGDDPESPHMRAARNVCRELGGAEQCNSFSKFFLAALG
QISYNACPNIPPEIVLLPKWIYFNLYAVSAWSRTMILPLAIVSAHRPVRKLSAKQGIGEL
FNKPAAANSSAGRLRGLPKSWREMFLLLDLSLKRYQKTAVTPLRPKALREAEKWLVEHLQ
GSDGLGAIFPPMVYILIVFKTLRYPSDHPLVQKAQRDLKDLFIRQNDTIRIQPCWSAVWD
TGIALNALAEFGIAPDHPIASKTTEWLLAKECRTACDWSKNCPDVEPSGWFFEFANPHYP
DVDDTAMVAMALRRLGGKPAQAALNRGLNWLLAMQNDDGGWAAFDRTRNRPILEHVPFAD
HNAIQDPSCPDIAARVLECLGHNGFDYRHPAVMKAVRFLRETQEAEGCWFGRWGVNYIYG
TWQVLTGLRLVGERMDQRFIRHAADWLRSCQKADGSWGESCQSYDNPKLKGQGPSTASQT
AWGAMGLMAVDGPHDPAVKNAIQWLMDHQTPTGDWEEPWFTGTGFPRVFYLKYHLYRLYF
PLMAIARFRRLGGNARRR
>A0A4P7DNI8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. S501|TrEMBL
MTATTDGSTGAANLRAAAASDPTESTSAAPDMMAVARHAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETVKAAARFIRGEQLGDGTWNTFYEGPPDLSATVEAY
VALRLAGDRPDDPHMIRAAGWVREQGGIAESRVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFTLDELHTDPACPNPSRPTAPAASW
DGVFQRLDKALHLYHKVAPRPLRRIAMNEAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVSPDHPAL
VRAADWMLGEEIVRPGDWAVRKPGLAPGGWAFEFHNVNYPDIDDTAEVALALRRVRHPDP
ARVDAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGRAHDPRTRRGVEWLLAEQEASGAWFGRWGVNYIYGTGSVVPALIAAGLPAGHP
SVRRAVDWLRSVQNDDGGWGEDLRSYREEKWIGHGSSTASQTGWALLALLAAGERETRSV
ERGVAWLAATQQADGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFATAT
AIGAGTGKGA
>A0A5C8SQG2|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium sp. WL69|TrEMBL
MREAFKKVEALQRPKTQEISIEDVERGITRATQALTALSHADGHLCFELEADATIPSEYI
MFHQFRATEIAPGLEAKIGNYLRRTQGKHGGWSLVHDGPFDMSASVKAYYALKFVGDSVE
APHMRRAREAILSRGGAANSNVFTRFLLALFGQVPWRAVPVMPVEIMHLPKWFPFHLDKV
SYWARCVIVPLLVLQAKKPLAKNPRGLGVAELFVTPPEHVRHWPGSPHATWPWTPIFGAI
DRVLQATQEHFPKKRRQRAVDKAEAWVSERLNGEDGLGAIFPAMVNTVLMYDVLGYAADH
PQVMIACEAIEKLVVVKEHEAYVQPCLSPVWDTALAGHALLEAGGPEAEHQARRGLDWLK
PLQVLDIKGDWAAGRPNVRPGGWAFQYANPHFPDLDDTAVVVMAMDRATRQHGLVADVPD
YANAISRAREWVEGLQSSDGGWAAFDADNNHHYLNHIPFSDHGALLDPPTADVTARVVSM
LAQLGETRDSSKALDRGVTYLLADQEEDGSWYGRWGMNFIYGTWSVLCALNAANVDPASP
EIRRAVAWLIRIQNPDGGWGEDASSYKIDPAFEPGYSTASQTAWALLALMAAGEADDPAV
VRGINYLTRTQGADGFWSEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKQSNTRT
VAFGM
>A0A6C1SRK9|squalene-hopene cyclase|EC 5.4.99.17|Rhodospirillales bacterium|TrEMBL
MGYVGRLSDPASNASATDASSLDRVIGETLGWLTRRQRPDGHWLFELEADTTIPAEYILL
NHFLDEVDDRTEAELAAYIRARQGTHGGWPLFPGGDLDVSASVKSYYALKLVGDDPDSPH
MTRAREAILAHGGAAKANVFTRIALALFDQVPWRAVPVIRVEAVLLPTWAPFHLDKVSYW
SRTVMVPLFVLAALKPKARNPRGVDIRELFVTPPERHRNYLTNPTGHWLGEVLLLLDRVA
RVAEPAIPRFLERKAIAKAMDFVRTRLNGEDGLGGIFPAMANAVMAFDALGYPRDHPDYV
TARGAIHRLLSRETGETLCQPCLSPVWDTSLALHTLLEAGCDESHATVRNATEWLRRTQV
LDVKGDWAGRKPDVRPGGWAFQYRNDHYPDVDDTAVVVMALQRVGSDAVREAVDRGVEWV
LGMQSDNGGWGAFDADNQHYFLDHMPFADHGALLDPPTADVSARCLGMLAQAGYGREHPA
VARAIRFLKDGQEDDGSWFGRWGTNYIYGTWSVLAALNAAGEDMNAPYVRKAVHWLKARQ
RPDGGWGEDCATYWPDRRDEVKASTPSQTAWALLALMAAGEVDSPAVAGGIAYLLEAPRD
EGKWREDLFNAVGFPRVFYLRYHGYSAYFPLWALARYRNLSQSNTRRVVHGL
>A0A5R9F7I5|squalene-hopene cyclase|EC 5.4.99.17|Alkalihalobacillus caeni|TrEMBL
MDTNLILKRIDSLKEELLSLQKEDGTWRFCFVNSLITDAYMIIVLRTLEIQGTEEEQIIK
SLVQRLLSQQSEDGAWRLYEDEREGNLDATIQAYNALLFSGYVNKNDENMKKAEKSIFRQ
GGLEKAHPITKAFLAANGQFNWPLNFHIPIGIMLLPRVLPINFFDFSSYGRIHFAPLLVL
LDKRFSIQTKWTPDLSNLHRKSLHSIKEEELRALLPFAKEMNTLLNIPSDLYQAALKKAE
EYMLKRIESDGTLYSYATATFLMVYALLALDYSKSSPVLLQAVNGLKDMICKTETSIHVQ
NSPSTIWDTSLISYALQEAGISCESTSIEKANDYLLMQQHYKYGDWAIKAPDVAPGGWGF
SETNSIHPDVDDTAAALRAITCSTEKSRTYRKAWHRGFNWVLGTQNSDGGWAAFEKDTTN
AFLSALPVRNAIDVLVEPSTADVTGRTLEFLGNKVGLRQDHPQVKRAIRWLLKNQEKSGS
WYGKWSICYIYGTWAALTGLKAVNISSSNKAIQKARNWLVTIQHPDGGWGESCKSDEARQ
FVPLNFSTPSQTSWALDALIACDRQPSSEIDAGIQKLVKDEWEEDAEIYPTGAGLPGGFY
IHYDSYKLIWPLLTLSHYMKKYKK
>A0A846DSJ8|squalene-hopene cyclase|EC 5.4.99.17|Desertifilum sp. SIO1I2|TrEMBL
MQTQDRVTETALQQGIRASQNYLLSLQNPQGYWWANLESNATITAEIVLLHKIWGTDKTR
PMAKIENYLRSQQVEQGGWELFYGDGGELSTSVEAYMALRLLGVSPEDPALQKAKAFILS
RGGIAKTRIFTKLHLALIGCYSWRGIPSIPPWLMLLPDEFPFNIYEMSSWARGSTVPLII
VCDRKPVYPLNPVINLDELYTERPDWTTAGLPRSGDWTDLFITLDDGFKLAETLNLVPFR
EEGIKAAEKWVLERQEVSGDWGGIIPAMLNSLLALHSLGYAADDPIVARGLQAVDNFGVE
TEKHYWVQPCVSPVWDTALVMRSLCDSGLAPDRPELVKAGEWLLEKQILDYGDWNVKNRQ
GKPGAWAFEFDNRFYPDVDDTAVVVMALNGVKLPNESLKELAIARAVAWIASMQCSPGGW
AAFDLDNHQDWLNSLPYGDLKAMIDPNTADVTARVLEMAIALNVNPLTPQAIQRALRYLE
REQEPEGCWFGRWGVNYIYGTSGVLVALSGVAPQTHRRSIERGVAWLLSCQNPDGGWGET
CWSYNDPSLKGQGSSTASQTAWALIGLMAASQATGDKMKTACDRGIAYLLQTQQPDGSWS
EPEFTGTGFPCHFYLNYHLYRQHFPLTALGRYQQLLTNAC
>A0A385NQ20|squalene-hopene cyclase|EC 5.4.99.17|Bacillus sp. Y1|TrEMBL
MRSEKLTKTKDHLIESLRDKQRRDGSWKFCFEGSLMTNAYMIILLRSLNIQTEETLIKRL
VNEICRKQENNGSWKLYYDERFGNLSNTIECYFALLYSGYLPRDSDVLQRAKSFIINNGG
LQKSEWLTKSMLAITGQIPWPTIIKLIPIEIMLLPTWSPISMFEIVGYARAHWVPIIICS
NKNFKNVHPQQPSLEDLNIDREEDHSQIDERSMKLISKIKSEAIKLAEIPEQIHEESFHK
GEAYMLERIESNGTLYSYFSSTFFMIYSLLALGYKKDHHIIKSAIEGMKSFLFEEKDLYY
IENSPSTVWDTALISNALHIAGVQNTDPMIASSTQYLLNHQHTTFGDWMINCPDTAPGGW
GFSPINTMVPDIDDTTAALRALAPSTIAKIIPSTGWKKGINWVLAMQNKDGGWAAFEKNI
TNRWLSFIPFRYEDRVLFDPSTADLTGRTLHFLGEYTNIERNSATIKKGINWLKKHQLED
GSWYGRWGICYIYGTWAAVTGLLACGVSRSDPSLKRAINWLNSIQNKNGGWGESCSSDIK
KKYTPLYASTPSQTAWALDALIYYYDKPTKEIEIGMEFLLSSFEKTNWTIEYPTGAGLPG
GFYIHYHSYNYIWPLVTISNYQRKYL
>A0A849SWT3|squalene-hopene cyclase|EC 5.4.99.17|Methylophilaceae bacterium|TrEMBL
MQTKVDEQLHISVGEAHASSVAALTGLSKTTPFEELDSALVCAREAIISRQSLQGYWVFD
LEADATIPAEYILLQHYLGTVELELQTRIAHYLRRKQQSNGGWPIFEEGASDISATVKAY
FALKVAGDLPDEPHMKKARELILSMGGAAKVNVFTRTTLALFGQLPWRTVVAMPIEIMLL
PKWFFFHLSKVSYWSRCVMTPLLILFNRQPVHTLPAEHCVTELFTSPPQNLRHLDHFIPG
RYLHNAFILLDSVLRFVDPLMPQKLRGRALRRADVWVREHMQGEGGIGGIFPAMANALMA
LKALGYDDNHPDMVRGTKAVNDLIVEQADEAYCQACVSPVWDTCLTINALIEAGVPESHP
AIKSSVAWLLKEQIFTRGDWCDLAPDLAPGGWAFQFENAQFPDVDDTCVVLMALLRAGAH
RNPHTLTEHIQPAVNWVLGMQSSDGSWGAFDINNNRLYLNNIPFADHGALLDPGTADLTA
RCIELLSMLGYNRHFPPIERGLAFVRKEQEENGAWFGRWGVNYIYGTWSVLCALNALGED
VGQPYIRKSVIWLNSCQNEDGGWGETCDSYDDAKLAGVGKSTASQTAWALLGLMAAGEVN
SNSVKRGIQYLVSSLNADGQWEEHLYTGTGFPKVFYLLYHGYSQYFPLWALGVYQSLRNG
DSTRQMSGLAAEPLLGTLPAQLAARKVNTRRAFS
>A0A7G6U8W4|squalene-hopene cyclase|EC 5.4.99.17|Tardiphaga robiniae|TrEMBL
MHSVSPEITIQNAALETSIASAKQGLLKFRQPDGHWVFELEADGTIPSEYVLLRHYLGES
VDAELEGKIANYLRRTQGKHGGWALVQDGDFDMSASVKVYFALKMIGDSTDAPHMVRARE
AIRSRGGAVNVNVFTRFLLAMFGILSWRATPVLPVEIMLLPMWFPFHLNKMSYWARTTIV
PLMVLAALKPRAQNKKGVGIDELFLEDPSRIGGIKRAPHQSRAMFAFFTGIDILLRAAEP
YFPKKLRAHSIAKAVEFCEERLNGEDGLGAIYPPMANMVMMYEVLGFPADYPPRAIQRRG
IDKLLIVGEVEAYCQPCVSPVWDTALTAHAMLETGGDEAFGPAKEGLDWLATKQVLDVKG
DWAVKRPDLRPGGWAFQYNNAYYPDLDDTAVVMMAMDRARRQTGGKEYDVALDRGREWIL
GMQSGDGGFAAFEVDNLEYYLNNIPFSDHGALLDPPTEDVTARCVSMLAQLGDTVETSKP
LADGVEYLRRTQLVEGSWYGRWGLNYIYGTWSVLCALNAVGIDHQDLAFRKAVAWLLSIQ
NEDGGWGEDAVSYRLDYKGFEAAPSTSSQTAWALLALMAAGEVDHPAVARGTRYLMDTQT
EKGLWDEARYTATGFPRVFYLRYHGYSKFFPLWALARFRNLKSTNSKTVGVGM
>A0A429NDC3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. WAC00469|TrEMBL
MTATTDASTGTALPSDAASASETEPSTPEAAGVRRAAAQAVRRATEYLLSKQDSEGWWKG
DLETNVTMDAEDLLLRQFLGILDEKTTHAAALFIRGEQREDGTWATFWGGPGDLSTTVEA
YVALRLAGDEPDAPHMAKASAWIREQGGIAATRVFTRIWLALFGWWKWEDLPELPPELIY
FPTWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAVPNPPRPFAPALS
WDGAFQRIDKALHAFRKVAPKRLRRAAINSAARWIIERQENDGCWGGIQPPAVYSIIALH
LLGYDLDHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHPQ
LVKAADWMLGEQVVRPGDWAVRRPTLPPGGWAFEFHNDNYPDIDDTAEVILALRRVRHPD
PERVDKAVGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAYEGLAHDPRTRRGIDWLLSEQEPSGAWFGRWGVNYIYGTGSVVPALIAAGLPGSH
PAIRRAVAWLESVQNDDGGWGEDLRSYKYSKEWAGKGASTASQTAWALMALLAAGEKDSK
AVERGIEWLASTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPVVG
KAVTAERSPAEVEGN
>A0A437MPS7|squalene-hopene cyclase|EC 5.4.99.17|Rhodovarius crocodyli|TrEMBL
MHELAVAEAPRGKILDTAIANAREALLSHQNADGHWVFELEADATIPAEYVMLQRFFGKR
DEAREAAIRRYLRRLQEQEAPTAQGGWPLFHDGALDISCSVKAYFALRLIGDAPDAAHMV
RARDAILAKGGAARSNVFTRGTLALFGMVPWRAVPVIPPEIMLLPSWFPFHIGKISYWAR
TVVVPLTVVNARRPKPLEPIGFDLRELFVQPPEEVREWPGGAHQQEPWATLFRALDWALQ
RAQRLFPRTHRARAEAACEGFVTERLNGEDGLGAIYPAMANAIWMYHCLGVPDTDPRVVT
AWAAIEKLVCERTDGEVYVQPCLSPIWDTALASHALLEVGGEEAASSVKRGLDWLVEREI
TDVVGDWAWQRPDLAPGGWAFQYANAHYPDVDDTAVVALAMDRYRREHGPIGEQMDASVT
RARNWVVGMQSKGGGWGAFDADNNYHYLNNIPFADHGALLDPPTVDVTGRCLAMLAQLEE
NGTKPAREAVDYVLAEQEADGAWYGRWGVNYVYGTWSALTALNAAGVSHQHPSMRRAVAW
LEGRQNADGGWGEDGDTYPGKGGTRPDELSRPGVSTSSQTAWALLALMAAGEVDSAAVAR
GARWLLEHQNAEGEWDEDDYTGTGFPRVFYLRYHGYRRIFPLWALARLRNLQNGNSRTVS
VGL
>A0A0P0RHZ8|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia caribensis MBA4|TrEMBL
MNDLSMTQTLGDALPRTLIDDHAPVAAALATGAAPVDALDAAVTRATDAILAAQQDDGHW
VYELEADATIPAEYVLLVHYLGETPNVELEQKIARYLRRIQLADGGWPLFTDGAMDVSAS
VKAYFALKMIGDPVDAEHMVRARECILAHGGAEAANVFTRILLALFGVVTWYAVPMMPVE
IMLLPKWFPFHLSKVSYWARTVIVPLLVLNAKRPVARNPRGVRIDELFRGAPVTTGLLPR
SGHQSKSWFAFFRAVDGVLRVTDGLFPKRSRERAIKAAVDFVDERLNGEDGLGAIFPAMA
NSVMMYDVLGYPADHPKRAIARQSIDKLLVIHEDEAYCQPCLSPVWDTSLAAHALLETGD
TRAEEAAERGLAWLRPLQILDVRGDWISRRPDVRPGGWAFQYNNAHYPDVDDTAVVALAM
HRSAALTQSDVDADAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPP
TADVSGRCLSMLAQLGEMPATSEPARRAYDYLLKEQEDDGSWYGRWGMNYIYGTWTALCA
LNAAGISHDDARIRRAAQWLVSIQNADGGWGEDGTSYKLDYRGYEKAPSIPSQTAWALLG
LMAVGYVDHPAVARGIEYLKSEQRDHGLWDETRFSATGFPRVFYLRYHGYRKFFPLWALA
RYRNLTRAGQKRVAFGL
>A0A6B2UZ39|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID10815|TrEMBL
MTATTDGSTGATLPTRAAAASEPVLTTPVAAGVHQAAEHAARRATDFLLSKQDAEGWWKG
DLETNVTMDAEDLLLRQFLGIQDEATTRAAALFIRGEQREDGTWATFYGGPGDLSATIEA
YVALRLAGDAPDAPHMARAAAWVRARGGIAAARVFTRIWLALFGWWKWEDLPELPPELIY
FPTWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPARPNPVKPTARAAS
WDGAFQRLDKALHAFRKVAPRRLRRSAMNTAARWIIERQENDGCWGGIQPPAVYSIIALH
LMGYDLQHPVMRAGLKSLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQ
LVKAADWMLGEEIVRPGDWSVRRPGLPPGGWAFEFHNDNYPDIDDTAEVALALRRVRHHD
PERLDKAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGLAHDPRTRRGIQWLLAEQEPDGSWFGRWGVNYIYGTGSVVPALTAAGLPASH
PAIRRAVAWLERVQNDDGGWGEDLRSYRDTKKWSGKGASTASQTAWALMALLAAGEKDSG
AVERGVRWLADTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFAA
EAPAGRPLAEAKGS
>A0A5P2HEG7|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus pauculus|TrEMBL
MNQAALSPRPITESPPRPDVSVRAALPDPLDAGIASAVDALLDQQQADGHWVYQLEADAT
IPAEYVLMVHYLGETPNLELERRIGRYLRRIQNADGGWPLFHEGAADVSASVKAYFALKM
IGEDPQAEHMVRARKAIHAMGGAEASNVFTRTMLALFGVMPWRAVPMMPVEIMLLPEWFP
FHLSKVSYWARTVIVPLLVLNSLRPRARNPRKIGIDELFLKPARTLGLPGKAPHQSRFWH
SVFTALDVVVRAAEPLFPRSARQRAIERARAFTVERLNGEDGLGAIFPAMANSVMMFDVL
GVPADDPNRAIARKSIDKLLVIDEDADEAYCQPCLSPVWDTSLAAHALLEAREPRAIAAA
ARGLDWLVPLQELDLIGDWAVRRPNVRPGGWAFQYRNAHYPDVDDTAVVGLAMHRADKEE
GTHRYDEAVARAREWMVGMQSSNGGWGAFEPENTHLYLNNIPFADHGALLDPPTADVSAR
CLALLCQIGEMPATSEPSARALRYLLDEQEANGSWYGRWGTNYIYGTWSALCALNAAGMG
ADAPEVQRAASWLIGIQNDDGGWGEDGDSYKLEYKGHEHAQSVASQTAWALLGLMAAGKG
HHPAVARGVDYLLRTQASHGLWDEARFTAVGFPRVFYLRYHGYARFFPLWAIARFRNLQR
EGNGALTWGM
>A0A6G8ZH46|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium symbiodeficiens|TrEMBL
MDSVNATSREAPQSGVLESSIASATQGVLGFQQPDGHWVFELEADCTIPAEYVLLRHYLA
EPVDTVLEAKIGNYLRRIQGAHGGWPLVHDGEFDMSASVKAYFALKVIGDPVDAPHMVRA
REAIHARGGAIHSNVFTRFMLAMFGVVTWRAVPVLPIEIVLLPFWSPFHINKISYWARTT
MVPLMVIAALKPRAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFLLFRSLDAILRVV
EPMFPKSLRKRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKDENFPPRAITR
RGIDKLLVIKDDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLDWLIPKQELEV
KGDWAVKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGATGYDAAIARGREW
IEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETAQTS
KHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVRHDDPMIRKAAAWLTS
IQNADGGWGEDAVSYRLDYKGWEAAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIAT
QDKKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A6I6RTF6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. GF20|TrEMBL
MTATTNGPAGAAPSRPAPARTTAATTDTAALDGAAVEAAAERARARAADHLLGLQSPEGW
WKGDLDTNVTMDAEDLLLRQFLGIRDEATTRSAALFIRGEQREDGTWATFHGGPPDLSTT
VEAYVALRLAGDSPDAPHMTRAAHWVRSQGGIAEARVFTRIWLALFGWWPWDRLPELPPE
LIFLPPWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPADPAPRARFAP
LASWNGAFQRLDRALHAYRKVAPRALRRAAMATAGRWIVERQENDGCWGGIQPPAVYSMI
ALHLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALADAGVPAD
HPQLVRAADWMLDEQIERPGDWSVRRPHLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVR
HPDTARMERAISLGVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDPPSADVT
AHVVEMLAAEGLAADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALVDAGLP
TTHPAIRRAVAWLESVQNDDGGWGEDLRSYREQGRMARGASTASQTGWALMALLAAGERE
SRAARRGVTFLAETQHEDGSWEEPYYTGTGFPWDFSINYHLYRQVFPLTALGRYTRGAAP
EGA
>B7JUY9|squalene-hopene cyclase|EC 5.4.99.17|Rippkaea orientalis (strain PCC 8801)|TrEMBL
MQTQNRVTSTQKVELSNLTKAIIASQNYIMSRQYPEGYWWGELESNITLTAETILLHKIW
KTDKTRPFHKVETYLRRQQNEQGGWELFYGDGGELSTSVEAYMALRLLGVTPEDPALIRA
KDFILSQGGISKTRIFTKFHLALIGCYDWKGIPSIPPWIMLFPDNFPFTIYEMSSWARES
TVPLLIVFDKKPIFEIEPAFNLDELYAEGVENVKYALPRNHNWSDIFLGLDKLFKWTEKN
NLVPFHKKSLQAAERWMLNHQQESGDWGGIMPPMVNSLIAFKVLNYDVADPSVQRGFEAI
DRFSIEEEDTYRVQACVSPVWDTAWVIRALVDSGLKPDHPSLVKAGEWLLDKQILEYGDW
AIKNKQGKPGGWAFEFINRFYPDLDDSAVVVMALNGIKLPDENCKKAAINRCLEWMATMQ
CKPGGWAAFDVDNDQAWINEIPYGDLKAMIDPNTADVTARVLEMVGSCGLKMDENRVQKA
LFYLEKEQESDGSWFGRWGVNYIYGTSGVLSALAVIAPNTHKPQMEKAVNWLISCQNEDG
GWGETCWSYNDPSLKGTGVSTASQTAWALIGLLDAGEALETLATDAIKRGINYLLDTQTP
DGTWEEAEFTGTGFPCHFYIRYHLYRHYFPLIALGRYWKIGLKNLKG
>A0A845DXL7|squalene-hopene cyclase|EC 5.4.99.17|Halobacillus litoralis|TrEMBL
MKEQIHEAIAQLAAEIHAHQTVDGSFHFCFENSLMTDANMILLLQTFTKEKDLIQQLCAR
LSSLQTEEGYWKLYADDAGNLSATIEAVFALLYAGYYSNEDLPVKKAKAFIRRHGGLNRA
HSLTKMTLAIHGEYPWPNLFHLPVHIILLPPSSPISFYDFSSYARVHMAPILLLSDQPFV
MKNKQIPDMSDCFIREDQELISKESRSLLTSVQDAVKSLAGLPHKLYLLSRQRLLTYMLQ
RIESDGTLYSYFTSTFYMIYALVSCGYQKHDPIIKKAIQGLIQHACSTDRGLHIQNSPSD
IWDTALLSHALQAPPTSDVPLHEAEQFLLKHQQTKFGDWMVATSHTEPGGWGFSKSNTIH
PDVDDTTAALRALRKDSSLQSHYTRGLKWVLAMQNEDGGWPAFEKGKTNPLMTFVPMDGA
EYASLDPSTADLTGRTLEFLGTDARFPLTDPRVQRALNWLRSHQENDGSWYGRWGITYIY
GTWAALTGMRAVGVSKDDRSIKKGIHFLESIQNEDGGWGESCKSDQEKSYIPLGDSTLSQ
TSWALAALMAVHERRTPSIERGISCLLRKLEAKDWTYEYPTGAGLPGHLYIYYHSYNYIW
PLLVLKKYLSLSS
>A0A6G7P0F3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. JB150|TrEMBL
MTTEAIDPAGTTADAADALPASVTRSLALAAAALRDRQDPSGHWKGEFETSLIGESGEVI
LHHFLRLPDDGRRAEAARTILAEQSPAGGWASYHGGPDELLLSVFCYVALRLAGHDKDEP
ELLAAAAAVRRLGGVESVDNLLMLAWLAVIGLWPWRDIPLVPAEIVLLPSRFPGNIFQFG
AAARGIVVANSLFMATRPVVPAGFDIRELFADPRTRRRLPRSRAVRAATTLSHWYGRHPV
GFLRRRALDKAASWLERTQETDGSWGGNWPQTANVVMGLDAIGLGRDHPVVRAALAGLDR
YVVERDARGHRRIEMWTSVVMDTALALTATVMAGGPAAESATGPAVRWLLDHQVTEPGDW
AVLTENPEPGGWPYEFTNNANPDCDDTSWAVAALRRLHPRGADPTVDQAIAKAVRWMESQ
QCADGGWAAFEPLRWNLPGRDALARIGFLEAPSADITGHVLEALGLDGRADTPAARRGIA
WLRRTQRADGSWPGWWACYHLHGTSAAVTGLTACGVPGSDPAVVRACDWITAHQQPDGGW
GEDIRALSDPDWVGRGESTPSQTGWALLALVAAGHTDAPAVRRGLEYLVRTQREDGDWDE
PQHTWVVHHDGLYWRDSLLRLIYPAMAMAAWTARAAGATGFGTAAHDDAHDDAEGTGAR
>Q2T2Q3|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)|TrEMBL
MHTLDATAAPAAPTVATGLDAAVARATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELERKIARYLRRIQLPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKSAPVNTGLLPKQPHQSAGWFAFFRAVDGVLR
LTDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARQSIEKLLVVGEDEAYCQPCLSPVWDTSLAAHALLETGDERAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNPDGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDHPAVARGIDHLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A540WH34|squalene-hopene cyclase|EC 5.4.99.17|Kitasatospora acidiphila|TrEMBL
MDRATIEDSLRRATEHLLSLQDDEGWWKGDLETNVTMDAEDLLLRQFLGIRTAEQTAATA
EWIRSQQREDGTWGTFHGGPPELSTSVEAYVALRLAGDDPEAPHMRAAAEYVRGAGGIAA
TRVFTRIWLALFGWWPWERLPEMPPEIMFLPKWLPLNIYAFGCWARQTIVPLTVVSALRP
VRPAPFALTELHTDPDNPFPLRPLAPPTTWDGFFERLDMVLHAYHKRAVRPLRRLALNQA
RRWIVERQEADGCWGGIQPPAVYSLIALHLLGYELDHPVMQAGLAAFERFTVHTEDGARW
LEACQSPVWDTCLATIALVDAGLAPDHPALVKATDWMLGEEITTRGDWSVQRPQLHPGGW
AFEFHNDTYPDIDDTAEVVLALRRVAPSHPRPQLVAAAADRGVTWNLGMQSKNGAWGAFD
VDNTSTLPNKLPFCDFGEVVDPPSADVTAHVVEMLAEVGMADDPRTRRGVEWLLANQEAD
GSWFGRWGTNYIYGTGSVLPALVAAGLPVSDPAIRRAVRWLEERQNQDGGWGEDMRSYED
PEKWSGRGDSTASQTAWALMALLAAGEGPDGRYAPGDGRGSAAVERGVRWLAATQLPEGS
WDEPQFTGTGFPWDFSINYHLYRLVFPVTALGRYLHGNPVLGQAGRAT
>A0A522L2D9|squalene-hopene cyclase|EC 5.4.99.17|Burkholderiaceae bacterium|TrEMBL
MKPGCTREILAGDNPQPTRRDARPTLPGSIDAACGALLGMQADDGHWLFELEADATIPAE
YVLLTHYLGEKPNQALEAKIAAYLRRIQGSHGGWPLFYDGAFNMSASVKAYFALKAIGES
VDAPYMQRAREAILAHGGAVHANMFTRILLAFFGVIDWKAVCMMPPEIMLLPKWFPFHLS
KVSYWARTVIVPLLVLQALRPRAANRLDITIDELFIESPRAIGPVRRAEHQNRLWFAIFA
GIDVLLHLADRWFPKKRRKRAIEAAVRFVDERLNGEDGLGAIFPAMANAVMMYDALGYPP
DHPQRATARRAIDKLLVIGETEAYCQPCLSPVWDTALAAHALIETGDPRAIKHAERGLDW
LTPLQILDVRGDWASRRPDVRPGGWAFQFANPHYPDVDDTAVVAMAMDRAGRSLGHDNYR
QAIDRACDWVIGMQSHNGGWGAFESENTCFYLNNIPFSDHGALLDSPTADVSARCLSMLS
QLPTTPERSASMARAVSYLIDAQEGDGSWYGRWGMNYIYGTWSALCALRAAGHGPDAPAM
QRGAQWLRSIQNKDGGWGENGDSYKLDYSGHETAPSTPSQTAWALLGLMAAGAVHEATVE
RGIDYLLSTQNKAGLWDEASFTATGFPRVFYLRYHGYGKFFPLWALARYRNLTGHDARTV
PGGM
>A0A7D7X4L1|squalene-hopene cyclase|EC 5.4.99.17|Granulicella sp. 5B5|TrEMBL
MSTQPYNSQAATSEAAKQPRFGRLDLALDKVIDGIHRSASWLLSQQHEDGYWCGELEADS
MLEADYIFVHTLLGTGDKGRLERCANEILRHQNADGGWSLHPGGPSNVNYGVKCYLALKL
MGWKADHPVLVRARENVLSLGGVVACNTFTKIYLCTLGQYDYDAVPAVPPEMLLFPNWFY
FNIYEISAWSRSILVPLSVIYAKKPFKKLPPEQSIDELFVGGRANSDLHLRWDRKHIFSW
RNFFLFTDRVAHLAERVHLRPLRKKALKKAERWMLDHFERSDGLGAIYPAMLNALVALVY
LGYSKDDPQFIRALDEFEKLGIDCPEGTPDYPTPTFRMQPCFSPVWDTAQVLSTLGEIGL
SRSDTRLVKAADWLLSKEIRYKGDWAHNVKNVDASCWCFFFNNDHQPDVDDTGEVLLALK
SVDNPRERYQHEVTQRAVEWVFAMQCRNGGWASFDKDNTKKMFESIPFADHNAMIDPPTV
DITGRILEMLASYGYTSRDKRVEKAIQFILDEQESDGSWFGRWGVNYLYGTFLVLRGLQA
MEYSHLEPAVQQAAEWIRMVQNADGGWGETCGTYDDPNKRGEGPSTPSQTAWALLGLLAA
NDTRSDSVAKGIRWLIERQHADGSWDELMPGRNGESYYTGTGFPRVFYLGYHLYKQYFPL
LALTTYRKAMERGEDAV
>A0A177HNB8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces jeddahensis|TrEMBL
MTATTDGSTGAVPPRAASASGTTGQAGTTESTPAAAGTREAATRALERATDFLLVRQDAQ
GWWKGDLETNVTMDAEDLLLRQFLGIRDEATTKAAALFVRGEQRDDGTWATFYGGPGELS
TTIEAYVALRLAGDSPDDPHMAKAAEWIREQGGIAASRVFTRIWLALFGWWKWDDLPELP
PELIYFPKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHSDPRNPSPPRRL
APVASWDGVFERLDKALHAYHKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYS
LIALHLLGYDLEHPVMRAGLESLDRYAVWRKDGARMIEACQSPVWDTCLATIALADAGLP
ADHPQLVKAADWMLGEQIVRPGDWSVRRPHLTPGGWAFEFHNDNYPDIDDTAEVVLALRR
VKHPDPDRVERAIDRGVHWNLGMQSKNGAWGAFDVDNDSSFPNRLPFCDFGEVIDPPSAD
VTAHVVEMLAADGKAHHPATRRGIEWLLAEQEANGSWFGRWGVNYVYGTGSVVPALTAAG
LPGSHPAIRRAVAWLESVQNDDGGWGEDLRSYRDVAGWSGRGASTASQTAWALLALLAAG
EQESKAVERGIAWLAETQGGDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYG
EPSFGKAS
>A0A177HK11|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces jeddahensis|TrEMBL
MIASGARPPAQVRRAIDSAAQQLFAVRRPDGSWQDHLPSAAISTATSAVALHFADPEGSA
ELIRSALDWLRANQLPTGGWGDGPGTPATLPASAFAVAALRLLAAEESREDVRRGLDWIE
SRGGMAAVADPDRCALHVLCLQFLALAGLYDERRIRRMPAAVALLPRKLRQKVSFVVPVT
LSWAVMQRRTWPQGRILRAVSRLAEPRAYAYFDELLLSQGKEGGMQESPLLVSMVCFAFA
RAGVRPDLVERMAGYLRLTARPDGSWAVNRDLEFSVTTFLAAGLQECGFADDPRLSSTID
WIRNCQWDAGFMATGCPPGGWAWSVESGWPNCDDTADALLALAGAGCGPTDPRVRAGLDW
LLAMQNRDGSWSCFCRDNHVALDAPCAVITSHAVAALRLAGGLGADAPPLAKAVRWFAKT
QRPDGSLPCLWYRGSTAGTGQVLDALGGLGLGGSDTARRARTWLLRTQQPDGGWGDGEGA
PSSVEETAWAVMGLLGAGADPREEAVQGGVRRLLHEQTSEALWEPTLLGVYFLDLWYSDD
LLASGYALQALGRYWKALT
>A0A844IHC8|squalene-hopene cyclase|EC 5.4.99.17|Aphanizomenon sp. UHCC 0183|TrEMBL
METQDRTKVNKVVDAIAASQKHLLSIQNPDGYWWAELESNVTITSEAVLLHKIWGTDKTR
PLHKVENYLRSQQREHGGWELFYGDGGDLSTTVEAYMALRLLGVSPTDPALLKAKSLILA
KGGISKTRIFTKLHLALIGCYNWRGLPSLPPWVMLLPDNFFFNIYELSSWARSSTVPLLI
VFDQKPVFKIDQPINLDELYAEGVNNVRWKLPKNGDWSDIFNILDDGFKLAESLNFVPFR
NEGIKAAENWILERQEVTGDWGGIIPAMLNSLLALKCLDYDANDPIIERGLKAVDNFAIE
IENSYCVQPCVSPVWDTAWAIRALIDSGFAPNNAPIVKAGEWLIEKQILDYGDWNVKNKQ
GKPGAWAFEFENRFYPDVDDSAVVVMALHQAKLPHEELKKQAINRALNWIATMQCKPGGW
AAFDIDNDQEWLNAVPYGDLKAMIDPNTADVTARVLEMLGACNLSIQPNNLEKSLDYLLK
EQETEGCWFGRWGVNYIYGTSGVLSALALINPLKYAGNINQGVNWLVKVQNSDGGWGETC
FSYNDPNLKGKGDSTASQTAWALIGLIAAGEATGKLALDSIEKGINYLLETQKSDGTWDE
IYFTGTGFPCHFYLKYHLYQQYFPLMALGRYQAIR
>A0A4Q0QXX6|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium zhanjiangense|TrEMBL
MDSVNATSREALDPSSLESSIASATQGVLGFQQPDGHWVFELEADCTIPAEYILLRHYLA
EPVDTVLEAKIGNYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDSIDAPHMVRA
REAIHARGGAIHSNVFTRFLLATFGVVTWSAVPVLPIEIVLLPFWSPFHLNKISYWARTT
MVPLMVIAALKPRAKNPKGIGIDELFLQDPRSIGMTAKAPHQSMAWFLLFRSLDAILRVI
EPMFPKSLRKRAIDAALAFIEERLNGEDGMGAIYPPMANIVMMYDALGKDANYPPRAITR
RGIDKLLVIRDDEAYCQPCVSPVWDTTLTAHALLEAGNAQAVPAAKRGLDWLIPKQELEV
KGDWAAKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGVTGYDAAIDRGREW
IEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETEKTS
KQVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDHKDPMIRKAAAWLAS
IQNEDGGWGEDAVSYRLDYKGWEAAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIAT
QNKKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A7C5XYW4|squalene-hopene cyclase|EC 5.4.99.17|Acidobacteria bacterium|TrEMBL
VNAYMALLLLGHDPAAPHIRSARQAIDDLLVDRGDMTYCQPCVSPVWDTGLAAHALLEES
RRENRPEVQKALDWLVDRQILNQPGDWKEKAPGANGGGWAFQYNNPWYPDLDDTALVAWA
IHEAGFRPEYAERVDLAADWLCSLQSRRGGFASFDPDNTAYFLNEIPFADHGALLDPPTA
DVTARCIALLRRLGRPKDRKAIERATFWLLEQQEENGSWFGRWGTNYIYGTWSALTALEG
CTERESCEAIERAADWLESVQHEDGGWGESNDTYEDPHRGCANDRSTAFQTAWALLGLLA
AGRVGSRSVQRGVQWLLEHQEADGLWSDPEFTAPGFPRVFYLKYHGYSRYFPLWALARYR
NLSLGTDPSGKVTV
>G4MJL3|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Paraburkholderia kirkii UZHbot1|TrEMBL
MNNLSLSAVGAQVSGSSLNSVINQATDTLLAAQHPEGYWLYELEADATIPAEYVLLVHYL
GETADEKLEAKIGRYLRRIQREDGGWPLFTDGAMDVSATVKAYFALKMIGDSPDAEHMQG
ARRAILAAGGAEKVNVFTRILLALFGVVSWRAVPMMPVEIMRLPMWFPFHLSKVSYWART
VSVPMLVLNAKRPRARNPHGVRIDEVFTNPPVNTGMPARSGHQSRGWFAFFRVVDSILRV
ADPLLPQAGRERAIDEAVRFVDERLNGEDGLGAIFPAMANSVMMYDVLGYPPEHPNRAIA
RKSLDKLLIIDEADDGEAYCQPCLSPVWDTSLAAHALLETGVPKARAAVTRGLDWLVPLQ
ILDVRGDWISRRSNVRPGGWAFQFANPHYPDVDDTAVVAMAMERADRENGTAMYGESIAR
AREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTVDVSARCLSMLAQLGET
SLNSEPARRAFDYIVKGQERDGSWYGRWGLNYIYGTWSAMCALNAAGVAPTDPRMKRAAD
WLIGIQNTDGGWGEDGESCKFDYRGYEQAPSTSSQTAWALMGLMAAGLVEHPAVAHGIDY
LMRTQQEHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLTREGLTRVTAAM
>A0A522Q0C8|squalene-hopene cyclase|EC 5.4.99.17|Acidobacteria bacterium|TrEMBL
MTREAGIELEPFKNGGADGTVVADLDLRVQQAIERAAEHLLSLQTPEGYWVGELQADSTL
ESDYVFFLHVVGQFDPERIAKLANYIRHRQLPDGGWNIYQGGPSELNATVKAYVALKLAG
DSADDPHMAAARSKIHKLGGLEQTNSYTRFYLALGGAVKWKHVPAIPPELMLPPKWFFFN
LYSLSSWTRAIVVPLTILYAKRPKWPVPAYARVDELFRDPSGHIPAFDWDRRVLTWRNLF
LAIDRLFKLHESLPWKPLRKIALAQAQKWLLDHLERSEGLGAIYPAMVNSIFALLAMGYS
ADDPLTARELAHLRGFEVEKGDTISLQPCMSPVWDTAIAMYSLEEAGLHPDHPALVKAAR
WLLDRQIVGPGDWQVKNQDAAPGGWAFEFRNDFYPDVDDASFVMMALQRVAYPDKVRLEH
ALRRSFRWLVSMQNRDGGWGAFDRNNDCSVLTRVPFADHNAMIDPSTADVTARVLECIAR
LGWPASHPAVQSGLSYLRKEQTAEGAWYGRWGVNYVYGTSGVLRMLEAFGLGRIQEAQRG
ADWLCAVQNRDGGFGESCASYDDPSLKGRGASTPSQTAWGLIGLLATRNVDDPAVIRSVQ
YLLEEQTEEGFWKEDEFTGTGFPRVFYLCYTLYRDTFPLYALAHYQSLRSKRGQTESIRF
SPAEFERHDGNGKKNGRN
>A0A4Q4DC72|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. L-9-10|TrEMBL
MGPRAASASEPTETITPAGGDLRVAAERATARSVEYLLGRQDAQGWWKGDLATNVTMDAE
DLLLRQFLGVQDARTTEASALFIRGEQRADGTWATFHGGPADLSATIEAYVALRLAGDSP
EDPHMARASHWVRERGGIARSRVFTRVWLALFGWWKWDDLPELPPELIFFPKWFPLNIYD
FGCWARQTIVPLTIVSAKRPVRPAPFALDELHSDPARPRPDKSFAPMTSWDGVFQRLDKA
LHAYHKVAPRRLRRTAMNAAARWIIERQENDGCWGGIQPPAVYSLIALHLLGYDLDHPIM
RAGLESLDRFAVRRADGARMIEACQSPVWDTCLATIALADAGLNPDHPALVKAADWMIGE
QIVRPGDWSVRRPGLPPGGWAFEFHNDNYPDIDDTAEVILALRRVRHPDAGRLDAAIERG
ARWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTAHVVEMLAFEGKSH
HPGTRRGIEWLLAEQETNGAWFGRWGVNYVYGTGSVVPALTAAGLPASHPAIRRAVAWLR
SVQNEDGGWGEDLRSYNDEAWIGRGATTASQTAWALLALLAAGERESKAVERGIAWLAGS
QREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGEPKPLAVRAGVRKGS
>A0A2N5N9Z7|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus pasadenensis|TrEMBL
MSDPARLASAAISRLQQELLRSQSGDGAWRMICESGVMSDAYLLILLQALGRPPQDEELI
RRIAARIASLQHEDGGWRLHADQREGHLESSVEAYYALLASGALEYGDPALVHARRFILE
RGGLTRVRAMMTQVLLAMTGQLPWPKELRLPVEALLAPSWLPLSLFDLSGHARAHLVPVL
MLSSGSFRLGEGRLPQLTELIAGEDRGFSLPTLLPEPLAGMLQAMADGHTPLYPASLERA
ERYLLERIEPNGTLLTYSTATMLMVAALLSIGYDPGDETIRRALDGVRSLVWQEPEEAEA
VEIAAAAAATGTASAPPEHAAAGPAPQPERAHLQIADSALWDTAMIANALLESGMPPEAD
AIQRAARWVAARQQSEAGDWRRRVPGVKPGGWGFSAVNTRYPDVDDTTAALLLLQRAAGK
SGGAPYWSEAAQERGSRWAWALQNRSGGWPAFERESGSPLIGLIQFEQSAQIVTDPPTVD
LTARTLQWAALASAPLPGWLAAALQAEDDDAETAAAAAAVRRACAWIVSQQDRDGSWAGR
WGICRVHGTGAALAGLLAVKAPRSASALYRGMQWLLSVQNGDGGWGESCASDVEGKYVPL
GASTPCQTAWALEGLLAHPHAPREAVERGIACLCALLEADDWRGRYPAGGGLPGHVYLHY
GSSRYIWPLRVLAQYVRRYGGGMPAEG
>A0A840ZP49|squalene-hopene cyclase|EC 5.4.99.17|Methylorubrum rhodinum|TrEMBL
MREAAGKVEQLHRPKTRDVSLADVERGVQDATRALTAMTQSDGHICFELEADATIPSEYI
LFHHFRATVPRDGLEAKIGNYLRRTQSKAHGGWALVHDGPFDISATVKAYFALKMIGDDI
EAAHMRAARKAILQRGGAANANVFTRILLALYGEVPWRAVPVMPVEVMHLPKWFPFHLDK
VSYWARCTMVPLFVIQAKKPRAINPRGIGVAELFVTPPESVRTWPGSPHATWPWTPIFGA
IDRVLQRTQDKFPKGIRQRAIDKAVAWTSERLNGEDGLGAIFPAMVNSVLMYEVLGYPPD
HPQVKIALEAIEKLVAEKDDEAYVQPCLSPVWDTALNSHAMLEAGGAQAEANARAGLDWL
KPLQVLDIKGDWAETKPNVRPGGWAFQYANPHYPDLDDTAVVVMAMDRAMRQHGLVSDMP
DYSNAIARAREWVEGLQSADGGWAAFDADNNHHYLNHIPFSDHGALLDPPTADVTARVVS
MLSQLGETRATSRALDRGVTYLLNDQEKDGSWYGRWGMNFIYGTWSVLCALNAAGVDPQS
PEIRKAVAWLIRIQNPDGGWGEDASSYKLNPEFEPGYSTASQTAWALLALMAAGEVDDPA
VARGVNYLLRTQGGDGLWSEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKRGNSR
EVQFGM
>A0A8E3TI23|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces chartreusis|TrEMBL
MTATTDGSTGARPPRAAAARETDSENPVAAGVYEAAEGAVRRATDFLLAKQDAQGWWKGD
LETNVTMDAEDLLLRQFLGVRDEKTTRAAALFIRGEQREDGTWGTFYGAPGELSTTIEAY
VALRLAGDAPDAPHMARASAWIREQGGIAAARVFTRIWLALFGWWKWEDLPELPPELIYF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHKDPADPNPLKPLAPAASW
DGAFQRLDKALHQLRKVAPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLQHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHAQL
VRAADWMLGEEIVRPGDWAVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHDP
ERLEKAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIRWLLAEQEPDGSWFGRWGVNYIYGTGSVVPALVAAGMPGSHP
AIRRAVTWLESVQNDDGGWGEDLRSYRYVKEWSGKGASTASQTGWALMALLAAGERDSKA
VERGVEWLAATQLADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFTDS
VVRVVVEDTAAVEAKGS
>A0A3N8BEF3|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp9126|TrEMBL
MNDLTDMPTLSAATVPAELETAVQRATDALLAAQQPDGHWVYELEADSTIPAEYILLVHY
LGETPNLELEQKIGRYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARKAIHAMGGAELSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPIARNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANSVMMYAALGYAEDHPNRAI
ARESVEKLLVVKDDEAYCQPCLSPVWDTSLAAHALLETEDPRAEEAVVRGLEWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANPHYPDVDDTAVVVMAMDRVEKLKHSDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETAA
NSEAARRSLDYMLKEQEPDGSWYGRWGMNFVYGTWTALCSLNAAGLGPEDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLDYRGYEQAPSTASQTAWALLGLMAAGEVNNPAVARGIDYLV
AEQQEHGLWDEARFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNATRVTVGM
>A0A847KSG7|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter sp|TrEMBL
MLDDVQTDRDSVSGGEWMQQINHDLLDRSVRDAHAALSKRQKSDGHWVFELEADATIPAE
YVLLEHFLDRINPELEQRIGVYLRRIQADHGGWPLYHDGAFNLSCSVKAYFALKCLGDDP
AAPHMQRAREAILAHGGAERSNVFTRFQLALFGEVPWHGTPVMPVELMLLPRSAFFSMWN
MSYWSRTVVAPLLVLAARKPIAVNPHGVHVQELFVTQPDKVTDWIRGPYHSPWGRFFKVL
DKALRPAMKLVPEKVHEKAIQAAIDFIEPRLNGVDGIGAIYPAMANVVMMYRVLGVSDED
PRAKTAWDAVQALLVNNGDETYCQPCVSPIWDTGLAGHAMIEAASGQWGTEPEKTKEDLD
RAAAWLRNLQILDVKGDWAINAPDVEPGGWAFQYRNDYYPDVDDTAVVGMLLHRQDDRAN
DVAIERARQWIIGMQSSNGGWGAFDIDNNKDLLNHIPFADHGALLDPPTADVTARCISFL
AQLGHPEDRQVIERALEYLRSDQEKDGSWFGRWGTNYIYGTWSVLCAFNAAHVSHDDPAI
VRAVEWLRSVQRSDGGWGEDCATYEGAKHGVYKESLASQTAWATLGLMAAGRRDDPATAK
GVAWLMERQKENGEWDEQPYNAVGFPKVFYLKYHGYRQFFPLMALARYRNLESSNTRKVA
FGF
>A0A4Q3BZE0|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobiaceae bacterium|TrEMBL
LGEVDPVLQDKCVAHIRRRQLEDGGWNIYEGGPSEVSASVKAYFALKLAGHSQNDPWMRE
ARACILRLGGIPRMNTYAKLYLALLGQFPWQYLPTVPAEIIFFPKWCFFNLYELSSWSRA
MLVPLAIINHFRPTRELSAEKQLHELYPVGTEKGFLGWQRDERYWTWRNFFLRCDRMLKL
LHKLPVKPWRTEALRHCEAWMLERMGEGSDGLGAIFPAMLNSMIALRALGYSSDHPMLVK
AKADFEGLFVDDPQDFRIQPCLSPVWDTAINAIALAESGIGANHPALQRAASWLQKKEVR
VHGDWAKVKNPYSEASGWAFEFNNIYYPDTDDTMMVLMALRLVKAPDGGDESEYSELFSR
ALRWLLSFQCRDGGWAAFDKNVTQRWLEDVPFADHNAILDPSCSDLTGRVLELLGYIGYP
RESRRVKRAIDFLMRTQETDGSWYGRWGVNYIYGTWQVLRGLRAMGQNMREPWIVRARDW
LESCQNDDGGWGETCASYDDPNLKGKGPSTASQTAWALMGLIAAAEGIEPNGVERRSIRA
GIEYLVSHQSADGSWPEAETTGTGFPKVFYLRYDMYRNNWPLLALATYRNYQAGSFHQPS
WFEYLSARPAELAGAQ
>A0A8I2D074|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia bacterium|TrEMBL
MRLAFRAGQQAQELEVPVGQTLCGLNDLATAIRRSQEYLLGEQRPEGYWIGELIVDCTLV
ADRLAYHHWNGKVDREWERKAINHLFSLQLPDGGWNIYHGGPAEVNATIKAYLALKLAGV
PETHLRMLRARSVALNLGGVPRMNTFSKLYLALLGLFPWKYVPTIPCEVLLIGKWFHVNF
WEMSNWSRAMLVPLAIINHFKPTRPLGQGISLDELYPEGYHDRDLRLQRDPQILTTRNFF
IWLDRLHKFAELFAHAGIHPFRRRALKRAEEWMLERFEGSDGLAAIFPAMLNSLIALKAL
GYPDDHPQVVRTEQHLKGLEHETSDTVRIEPCFSPVWDTAITLIALAESGVPPEDPRLQR
ATEWLLSKEIRFRGDWRHKNPANVEPSGWVFEFENKWNPDVDDTAMVLLALRLVPTSDSR
RDEAYERGLKWMLTFQCKDGGWAAFDKDCTKNVLTKVPFADHNAMLDPECADITARILEV
LGHERFPLNHPQVVKAIEYLRDQQEPDGSWYGRWGVNYLYGTWQVLRGLHTLGIDMHQPW
LLQARDWLESVQHKDGGWGERVDTYEDPVFKGRGPSTASQTAWVVMGLCTFGDPNRPSLI
RGVEYLVRTQNRDGSWSEDEITGTGFPKVFYLKYDMYRNSWPLLALATYRRLSDGLAPER
RH
>A0A6N8F0C2|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus macerans|TrEMBL
MGHVISGVGREIGRLTDELVRRQQPDGTWRYCFENGTAMDASVIVLLRSLSAGSEELIRS
LHDRILAAQQPEGCWRWFEDEREGNLSATVEAYYALLFSGYSRPEDEPIRRARNYIQAAG
GIGMAGGLLTKALLAATGQRKWPVALSSIPLEILLLPPSFPVSFFDFSGYSRVHLVPLLI
MADRDFSLKTPHTPDLSDLYGGGRGLDEEELSRENRDLLAHIQAGIGRLIGSPQRIRQAA
VKKAEQYMLERIEADGSLYTYASCTVLMVFALLALGYDRRDPLITHAVDGLAAMRCSAGG
TGGEITIQNSPSTVWDTALIAYALQEAGLSEDHAAIRKAAAYLRSRQHRKAGDWQIHNPG
VAPGGWGFSDTNTIIPDVDDSTAALRAIHSLAGREPACLEAWNRGLNWVLSMQNDDGGWP
AFEKNTNKEMLTWLAIDGAKAAAIDPSEADLTGRTLEFLGNFARLDARHEFIRRGADWLI
RHQEADGSWYGRWGICYIYGTWAALTGLKAAGLASDHEAVAQGVSWLLSVRNPDGGWGES
CRSDREERYVPLRASTPSQTAWALDALIAAHDRPTTEIDQGIARLIAMLHEDGWTASYPT
GAGLPGYFYVHYHSYRYIWPLLALGHYRKKYGGD
>A0A4R4RGV7|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. KC345|TrEMBL
MTAVEAGTGTRTAAEALEAAREHLLLLQSPEGWWKGELQTNVTMDAEDLLLREFLGIRTS
GDTGETARWIRSQQAPDGTWATFHDGPPDLSTTVEAYTALRLAGDPPDAGHMIRAAAYIR
SEGGVPATRVFTRFWLAMFGEWPWDDLPVLPPEMMFLPRWFPLNVYDWACWARQTIVPLA
VVGAFRPVRPLPFGLDELTPDYHVPRRRAPGLPGWDEAFEALDRALHVYERRPVKPLRRA
ALRRAADWIIARQERDGSWGGIQPPMVYSLLALNLLGYGIDHPVVRRGLDGLERFTIRDE
KGRRIEACQSPVWDTVLAMNALADAGLPSGHPALERAADWVIGEEVTGPGDWSVRRPDLP
PGGWAFEFDNDCYPDTDDTAEAVIALNRVQHPKAEPAIERGVRWMAGMASRDGGFGAFDA
DNTRDLCRKLPFCDFGEVIDPPSADVTAHVVEAMSHRGMADSLTVKRAVVWLLKAQEPDG
SWFGRWGANHVYGTGAVVPALIAAGVRPGKPAIRDAVRWLERHQRDDGGWGEDLRSYRDR
SWVGQGVSTPSQTAWALMALLAAGERGRAVERGIGWLAERQRPDGTWDEDHFTGTGFPGD
FYINYHLYRLVFPLSALGRYLKGA
>A0A3L7S9Q2|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MTFTGSNTGSPDGSTRLLDIAPSAARHHARPSLRVPLSPPRQDRPPAPGLNAVASRTAEW
LIDRQADDGHWRGPLEGDTILESEYLLILAWAGRLGGPVTEAAARRILAEQLPEGGWAIY
PGGPVDVSASVKAYFALKLTGHDPQSPELSRARRAIAAAGGPWAVNSFTKFYLALLGQLP
YSACPAVPPEMVLLPDWFPVNLLRVSAWSRTMIVPLSLMWAFKPVRTVPEREGISELFAA
TPMRRSPDAGGWARFFRGVDRVMKACEALGLVPLRARAVQACRRWMLERFDGSDGLGAIF
PPIVWSIVALRALGCDEDSPEVRECWRQLDRLVEHEADGSVRLEPCRSPVWDTAITAIGL
VEAAALRESEGREMSRAATAGIDWLLANEVRGSGDWARGVPAASRVEPSGWSFQYANRFY
PDIDDTAMVVIALVTWQRHAARQANAGGDPRWDLVTAAIGRATRWLLAMQSSDGGWGAFD
RDNNLEILCKVPFADHNAMIDPSTPDIAGRVLEAFGKAGLRHGHPAVDRGIEYLRRVQEP
TGAWFGRWGVNYVYGTWQALEGLRAVGVGLDDPCVSRAADWLEAHQQADGGWGESPESYA
DPGLAGVGPTTASQTAWGLAGLVAAGRGGSAVVGRGLAWLADRQQPDGTWSQPEFTGTGF
PQVFYLRYHYYPIYFPLVAICRGLSADVNTGWSS
>A0A7K2GC06|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4950|TrEMBL
MTATTDGSTGAMPPRAAAASDTAGTTPETAGVHHTAVDAVRRATDFLLAQQDPQGWWKGD
LETNVTMDAEDLLLRQFLGILDEATLRASALHVRGEQRPDGTWATFFGGPGELSTTIEAY
VALRLAGDRPDAPHMARASAWIRARGGIAEARVFTRIWLALFGWWKWEDLPELPPELLYF
PKWFPLNIYNFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDKDRPNPPKPLAPPTTW
DGLFQRLDKVVRGYRTVAVRGLRTAALKYATRWIVERQENDGCWGGIQPPAVYSVIALHL
MGYDLQHPVMRAGLESLDRYAVWRQDGARMIEACQSPVWDTCLAAIALVDAGVPADHPQL
VRAADWMLGEEIVRPGDWAVRRPQLPPGGWAFEFHNDNYPDIDDTAEVALALRRVRHRDP
ERVDRAIGRAVRWNLGMQSRNGGWGAFDVDNTSPFPDRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIDWLLGQQEPDGSWFGRWGVNYIYGTGSVVPALTAAGFPGSHP
AIRRAVGWLQTVQNEDGGWGEDLRSYQDAARWSGRGASTASQTGWALMALLAAGERDSRA
VERGVEWLAATQREDGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGEPFAKK
PFPEVEGG
>A0A6M0BUI2|squalene-hopene cyclase|EC 5.4.99.17|Okeania sp. SIO2H7|TrEMBL
GDWGGIIPAMLNSMLALRCLEYDVADPVVVQGLEAIDKFAVETEYDYWVQPCVSPVWDTA
WVIRSLVDSGIPPSHPAVLKAGEWLLQQQILDYGDWAIKNKLGKPGGWAFEFINRFYPDI
DDTAVVVMALDAVELPDEELKRVAIARAMEWVASMQCQPGGWAAFDVDNDQDWLNGIPYG
DLKAMIDPNTADVTARVLEMVGCCRLSMDSWRVKRAIAYLEREQEGEGCWFGRWGVNYIY
GTSGVISALAVVAQESHRDFIEKGASWLVGCQNSDGGWGESCWSYNDPSLKGKGKSTASQ
TAWALIGLLAAGEATGNFAREAIDGGVDFLVSTQKDDGSWLESEFTGTGFPCHFYIKYHF
YPQYFPLMALGKYENLLSG
>A0A6L7WWP6|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MSVEVSARPNALANAIERARRHLLGLQHPEGWWKGELESNVTIEAEDLFLRRYLGILDAG
TTERTARWIRSRRQPDGTWANFHGGPPDLHTTTEAYVALRLAGDQPGDEIMRQTAAWIRE
QGGVEATRTFTRFWFALNGWWSWDDVPAMPPEVMLLPPWWPLNIYDFACWARQTYVALTI
VRSREPACPAPFPIDELRTHCMPPMDQSLLSWTGIFNQVDRLLRWYQKRPIGWLRKAALS
RAEAWIVRRQERDGSWGGIQPAWVNSIIALTLRGYPLDHPMIARALDGLDTFTIDDGHTR
RLEACQSPVWDTAMAIEALNDSGTAGDDARLIRAADWLLDQEVRVKGDWSVRRPHLAPSG
WAFEFANDNYPDVDDTAEVGLALRRVDHPDPDRVDAALVRARGWLEGMQSRNGGWGAFDA
DNTNTLCRQPSFRDFGEVIDPPAADVSARALQFLAQEDALDTETARRGLAWVRAEQETDG
SWFGRWGANHIYGLSVVVPALVAAGTPANDPALRRAVAWLEAHQNADGGWGEDLRSYSDP
AWIGRGASTASQTAWALLALLEADDESPAIQPGIEYLVRTQREDGNWNEDLYTGTGFPGA
FYINYHLYRLLFPLMALGRYARKVGRDEDGM
>A0A7Z2GKP9|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia acidisoli|TrEMBL
MKNSGQSFTFSTATKALLDAAIVRGRESLARLQAEDGSWCFELESDATITAEYILMMHFM
GKIDTVRQEKMARYLRDIQRLQTHGAWDLYVDGAPDVSCSVKAYFALKAAGDAASAPHMV
RARETILALGGAAKSNVFTRILLATFGQVPWRATPFMPIEFVLFPKWVPISMYKVAYWAR
TTMVPLLALCSLRARAANPHHVSISELFVTPAEEEREYFPRGKGIRRFFLAMDRAVRHIE
PLMPKSLRKRAMAHAEAWCAERMNGEDGMGGIFPPIVYSYQMMQVLGYPEDHPLRRDCEN
ALEKLLVERRDGSMYCQPCLSPVWDTAWSTMALEQSRVATASATQANALSDAELQQRITR
AYDWLAARQIDTVRGDWIENAQPDTPVGGWAFQYENPYYPDIDDTAVVAAMLHRRGRAQA
RATGTDPYAARVTRALDWMRGLQSRNGGFAAFDADCDRLYLNAIPFADHGALLDPPTEDV
SGRVLLCFGVTGRAQDKAALARAIDYVKATQQPDGSWWGRWGTNYIYGTWSVLAGLALAG
EDAQAPYIARALAWLRARQNADGGWGETNDSYLDAALAGRNGGESASNFTAWALLAQMAF
GDWESESVRRGVAYLLSVQGSDGFWWHRSHNAPGFPRIYYLKYHGYTAYFPLWALSRYRR
LAKVDVAVEAKELVEA
>Q2RYC8|squalene-hopene cyclase|EC 5.4.99.17|Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1)|TrEMBL
MDATAPLRDPGAPSAENCSVDRRELDDVIGESCRWLGERQNQDGHWVFELEADATIPAEY
ILLNHFLDEIDDAREARIASYLRAIQGKHGGWPLFHDGDFDMSATVKAYYALKLTGDGVD
EPHMVRARQAILEHGGAERTNVFTRFTLAMFDQVPWRACPVTPVEALLLPRFAPFHWSKV
SYWSRTVMTPLMILYSRRARAVNPRGIGVRELFRRDPEVIRDWLKNPTGHWIGDALIQID
KVLRVIEPAIHWAFRDRAEKWALDFIEERLNGRDGLGGIYPAIANTLMAYHTLGYAKDHP
GYRIAREAVDGLCTPHAKGEYVQPCLSPVWDTCLASHAIQEAGQSAGDRAVDQSNAWLRE
RQVLDVVGDWKSNRGHLRPGGWAFQYNNPHYPDVDDTAVVVMALARSKEDEANREAIARA
EEWIIGMQSSNGGWGAFDAENEHDFLNHVPFADHGALLDPPTVDVSARCLGMLAQLGRPK
TDPVVARGLDYLWREQEADGSWFGRWGTNYIYGTWSALNAFNAVEWDMTDPRICKAVDWL
KSRQRDDGGWGEDCATYWKERRSVSKASTPSQTAWAVLGLMAAGEVDSPEVERGIRYLLE
APRDGGKWEEELYNAVGFPRIFYLRYHGYSAYFPLWALARYRNLTSGNCKRTIHGM
>A0A1D3RPA0|squalene-hopene cyclase|EC 5.4.99.17|methanotrophic endosymbiont of Bathymodiolus azoricus|TrEMBL
MIDYSWTECSAACVVALLEILELYPDYKRSEIEHAITDGLKFIVKQQKMDGSWYGGWAVC
FTYATWFGIEALVQGKDYIDAQLRTNCINKACDFLLSKQMTDGGWGETYESCAKMVYSQA
ETSQVVNTAWALLALQAAKSPEKTALQRGINLLLDRQLENGDWAQENISGVFNYNCMITY
SAYRNIFPIWALNRFYQHKHY
>A0A3N7ZN04|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp9131|TrEMBL
MIRRMNKPAPSSWSALDTAIARGRDALMRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDARQEQMARYLRAIQRLDTHGGWDLYVDGDPDVSCSVKAYFALKAAGDSEQAPHMVRA
RDAILKLGGAARANVFTRILLATFGQVPWRAAPFMPVEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNIAIPELFVTPPDQERQYFPPARGMRRAFLALDRVVRHVEPL
LPKRLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMDVLGYPDDHPLRRDCENAL
EKLLVTRPDGSVYCQPCLSPVWDTAWSTMALEQARGVAAPDAGAPSGSQNELDACIARAY
DWLAERQVNDLRGDWIENASADTQPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRTHRNA
DGSHPYAARVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRAADRASLARAIDYVKRTQQPDGSWWGRWGTNYIYGTWSVLAGLALAGED
PAQPYIARALAWLRARQHADGGWGETNDSYIDPALAGTNAGESTSNFTAWALLAQMAFGD
CESDSVKRGIAYLQSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GTALAGTSSSSGAGVSASRTTDAALA
>A0A7Z9GMG0|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirales bacterium|TrEMBL
MEQSIHYLLNQQDPRGFWVAELEADSTLTSEYIMLRRMLKKVDPEKERKKVSYLKAAQCA
DGGWPIYYGGPSNISASVKAYFALKLAGVSPDEPSMHNAREVILKMGGVVNTNVFTKIAL
ALFGQYDWQGIPSMPPEIILLPKQFPVSIHSVSYWSRVVLVPLLIIYASQPVSQVPKECG
IDELYVVPRNQIHVRRGPPFEADPRPVSWRNLFLLVDFALHLYSQRPLRPLRGLAIKKAT
DWMLERMQGNGGLGAIYPAMANSVLALHALGYGTDHPLVTKALSEIEELEVESEDMLHLQ
PCFSPIWDTCLLTNTLVESGLSRTHPGLLKAGHWMLSQQTKKVGDWKVSAPQAQPGGWCF
QFENEHYPDCDDTAVVLMALAKLDFPNKTEQRQAIIRGLQWLLPMQGRDGGWASYDKDNN
ATMFNEHPFADHKSLIDGSTADIVGRVLEMLGVLGFDRTFRPARKAIAYLKKDQEANGSW
YGRWGVNYIYGTWSVLAGLRSIGEDLSQPYIRKAVHWLKETQHDDGGWGESCQSYADQSL
AGVGESTASQTAWALIGLLCAGEVQSDNVTRGIESLIRSQKPDGSWEERFHTGTGFPRVF
YLRYHWYGQYFPLWAFSMYHSLKTRSRLRADDIAKHNRNQGWYVQHSKKI
>A0A532D7Y0|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp|TrEMBL
MKLLKHLMTRLSDRLFAHGGSLHAGPQAQGTGPSLRLVSHNPQASSTPDQSGRRQTGCHI
PGQSEVIDDAVRKSQAWFFRQQDSQGFWAAELEADSTLTSEYLMLRRFLGVVDQAREAKA
VRYLRAAQLPDGGWPIYTDGPSEISASVKAYFALKLVGVSAEEPFMLQAKDGILDKGGVV
SANVFSKITLALFGQYDWRGVPSMPPEVLFFPKRFYFSVYAMSYWSRAVLVPLLIVFAHK
PLCRLEPHQGISELYLTPPEQVSYRRERPFNRDAAMFTWRNCFITVDAFLKLYDRLPVKP
FRRLALERAAAWMLDHIKGSGGLGAIYPAMANSVVALRCLGYPVDHPLVVKALREIEALE
VHDVVTDETGDAPAMHLQPCFSPSWDTALLMNALVEAGVGQNHPALIKAADWLLSCQANT
VGDWKVSAPEAEPGGWYFQFENACYPDVDDSAVVIMALAKLHMPDRSAQRGSIVRGARWV
LAMQNTDGGWGAYDKDNNHMVFNLIPFADHRALLDPSTADLAGRCLEMLGTLGYDQSHPA
AHRALAFLRREQEADGSWY
>A0A3N9RZ36|squalene-hopene cyclase|EC 5.4.99.17|Novosphingobium sp. LASN5T|TrEMBL
MTDPLAAVDAAVDRAASALSGAQRADGHWVFELEADCTIPAEYVLLRHYLGEPVAEELEA
KIGRYLRRTQSDEHHGWGLFHKGAFDVSATVKAYYALKMIGDDPAAPHMVRAREAVHKAG
GAEAVNVFTRIQLALFDAGPWSVVPTMPPELILLPRWFPIHLSKMSYWARTVVVPLLVLC
AKKPVARNAKGIKVDELYTRRPIDRKTQAADPKWVWTKSFNALDKVLKVAEGHWPRTLHQ
RAIDTCAAWVTERLNGEDGLGAIYPAMANSVMMYDVLGYPKDHPARAIARQSVENLLVIH
EDEAYCQPCVSPVWDTALAAHAMLEAGGADNAARAEAALDWLKPRQVLDVEGDWAEERPG
VRPGGWAFQYNNAHYPDLDDTAVVVMAMDRAQVADRMPIDRGVEWTVGLQSRNGGWGAFD
ADNDYDYLNNLPFADHGALLDPPTADVSARCVSMLAQLGEGLDSPRMAAAIAYLRKEQEP
EGSWFGRWGVNYIYGTWSVLCALNAAGLPAEDPAVARAVGWLKAIQNPDGGWGEDCDSYA
LDRKGHVPAPSTASQTAWALLGLMAAGEADSEAVKRGVDWLVANQEADGLWGQEYYTGGG
FPRVFYLRYHGYPKYFPLWAVARYRNLKRSNTRQVAFGM
>A0A849EAN1|squalene-hopene cyclase|EC 5.4.99.17|Anderseniella sp|TrEMBL
MQSNVYVLRPESGTSPTLVSDSANTARDAGEHLLAMQQNDGHIVFELEADATIPAEYIFL
NHFLDKREPQLETELGEYLRSLQSKTHGGWPLFHEGGFNISASVKAYFALKMLGDDKNAP
HMIKARNAILAHGGAEKSNVFCRYSLALFGQIPWRGVPAMPVELMLMPKWFPANIWKFAY
WSRTVIAPLTILAALKPMARNPMNASCREIFCEPPEDIKVWNFNHTGSRWGEFFLQIDKL
LHPAEKHVFPRMKFRKWAIQRSLDFIKPRLNGEDGLGAIFPAMANTVMAYDALGYSPDHE
DFITALSSCRKLVTENRELRGDKPRYVQPCVSPIWDTSLAAHGLLEAGVAPDDKRIIAMC
DWLRDLQILDVKGDWAINAPDLEPGGWAFQYRNDHYPDVDDTAVVGMLLHRVDPDRYAES
IRRAVVWIEGRQSKNGGWGAFDIDNNADFLNTIPFADH
>A0A525WGI2|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp. CG24E|TrEMBL
MKLIRTLLDRLSDSLFVSVPEMRGLAAEPSNIPPLRLVSDKPVLSAPVDTAARRPTNPIS
QMDALDDAVRRSQGWFLSRQHTTEGYWVAELEADTTLTAEYLMLRRFLERVDPERERRAV
HYLRAMQLPDGGWPIFYGGPSEISASVKAYFALKLSGVSVDEPFMVRAKDCVLAKGGVVQ
ANVFTKIALALFDQYDWEGVPHMPVELMLLPKGFYFNIYAISYWSRAVLVPLLIIFAHRP
VCQIPREQGIEELYLIPRKEIRYWKFPPFNKDQKWFTPHNLFVALDAMLKLYDRMPLLWL
REKAVHRTATWMLEHIKGSGGLGAIYPAMSNSIIALQCLGYQVDDPLVRKALHEIEALEV
YDKASIGDQRVDTLHLQPCHSPIWDTALLLNALIETGMPQDHPSLQKAAAYLVSRQTKTV
GDWKFSSPDAEPGGWYFQFENELYPDVDDSAVVLMGLSKIQMSQTTDLQESIQRGMKWVL
AMQGSDGGWGAYDKDNNRIVFNYIPFADHHALLDPSTSDLTGRCLEMLAALGYDQTHPAV
APALRFLKREQEADGSWFGRWGVNYIYGTWSVLAGLHAIGEDLSKPYVRRAITWLESKQN
PDGGWGESCLSYGDPAWSGKGDSTPSQTAWAIMGLMSAGMADAFSVARGVQYLLRHQTKD
GSWEEVRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRTRGKMRADEVRQQVLASGCH
RADR
>A0A7K1XQZ3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. XHT-2|TrEMBL
MTATTDGSTGAASPSRLTAASEHDTDSPEAAGVPDIAARAVRRATDFLLSRQSDEGWWKG
DLETNVTMDAEDLLLRQFLGILDEDTTRAAALFIRGEQREDGTWASFYGGPGELSTTIEA
YVALRLAGDAPDAEHMAKASAWIREQGGIAASRVFTRIWLALFGWWKWEDLPELPPELIW
FPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPANPSPPRPLAPANT
WDGAFQRLDKGLHALRKAVPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLNHPVVRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHPQ
LVKAADWMLGEQVVRPGDWSVRRPHLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHHD
PERLDNAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGLAQDPRTRRGVEWLLAEQEPDGSWFGRWGVNYLYGTGSVVPALTAAGIPTSH
PAIRRAVAWLEKVQNEDGGWGEDLRSYRHAREWSGKGASTASQTAWALMALLAAGERDSE
AVARGVAWLANTQKEDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFTA
KPAEATAAAGSAQALADAKGS
>A0A6I7PYF5|squalene-hopene cyclase|EC 5.4.99.17|Bradymonadales bacterium|TrEMBL
MNTSLQTPESKSQILTPGHLEELLSHLEACLWQKQAVDGHWHYPLDDSVTMNAEYIFFLF
WMNLDEKDLIQRLANFLLQQQNEDGSWSLYYGGSPHLSSSVEAYLALRLAGFSKEDPRML
KAAQAIRSEGGPPRSRVFTKIWLALFELHPWDGVPMIPPEILLNPKGSPFHILEFSYWSR
SVIIPLTILFHIKKTYGVNFDLSELYPSKDSEQDLGYAPVIPVDESWIHKSYQQSLQWIK
WDSLFFGLNRAFNFYETGLTVKPFRQLAVQKAKTWILEHQDESGDWGGIMPAIMNSLMAL
RALGEELDSAPIAKGLQALKRLCRGESDSIRSHAHESEETVCLQSCVSPVWDTALATLAL
LESGVKPTDPRLQRAKSWLWSQRITRKGDWIHKSLISPHEPTAAWCFQYHNDFFPDLDDT
ALVIFVLHRLGMGLEELEPALRFVFGMQNRDGGWGTFDRENTQWILNEIPFADLRSLIDP
SNPDVTGHLLEALGGLGLSDRREVRAAVKYLKSCQRPGGSWYGRWGVNLLYGTCAATVGL
RAVGEAQDSECLQRAAEFVLKQQNPDGGWGEDCDNYLPETQRAEGKSTPSQTAWALMSLE
ACGFQDRERKEAVDRGIEFLKSRQIEDGLLEPEFTGTGFPRHFYLRYDGYRLYFPLIALG
RIQSSSNSSSS
>A0A5D4SXS0|squalene-hopene cyclase|EC 5.4.99.17|Sutcliffiella horikoshii|TrEMBL
MNPVDKINEKLKDMISNLLSKQKDNGVWNFCFEGSIMTDAYMIILIRILELTDEEVLVKS
LVERIKSQQESNGAWKVYPDEDGGNLSVTIEGYFSLLYSGYVAKNAGYMRKAERFIQENG
GLSKSDWLTKMMLAITGQIKWPSIIKIIPIEIMLLPSRSPISIYQFVGYARAHWIPILIC
SNLNYSYVHSRTPNLTHLQGGGSDDEDQRLLEDMQNLQLYFKNALKKLAGSTENLKRKAF
IKAEDYILERIEENGTLYSYFSASFFMVFALLALGYDKKNPLIGNAFQGMKAYLCRSADQ
VFIQNSPSTVWDTALLSAALQQAGVPHQHASIMKASNYLLSRQQQKYGDWAIKNPDVTPG
GWGFSDTNTFVPDIDDTTAALRAITPLAGTENHFKHAWNKGVEWVLTMQNDDGGWSAFEK
NTDNYLLSFIPSKYEDRVLFDPSTADLTGRTLYFLGEYTTMPQESDVFQKAREWFEHNQE
ENGSWYGRWGNCYIYGTWAAITGLKAIGVSSDNPLISRGVKWLLSIQNEDGGWGESCESD
SKKRYVPLHHSTPSQTAWALDALISASEIPTPKIEKGMHSLLSLLEASDWRSIYPTGAGI
PGGYYIHYHSYKYIWPLHALSHYKNKYYEIE
>B9B0U8|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia multivorans CGD1|TrEMBL
MNDLTDMATLSAGTVPAELDAAVARATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRAVDHVLR
AVDGLFPAYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKSIEKLLVVHEDEAYCQPCLSPVWDTSLAAHALLETRDPRAEQAAVRGLDWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANPHYPDVDDTAVVAMAMDRAQKLNQSDTYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETAL
NSDAARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCALNAAGLGPEDARVKRAAQWL
LSIQNKDGGWGEDGDSYKLNYRGYEPAPSTASQTAWALLGLMAAGEVNNPAVKRGIDYLI
AEQKEHGLWDEARFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNTTRVTVGI
>A0A6B2YEP7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID14446|TrEMBL
MTATTDGSTGALPPRAASASEIQHDTPAAAGTVETRDAATRAMARATDFLLALQDDQGWW
KGDLETNVTMDAEDLLLRQFLGIRDEPTTRGAALFIRGEQREDGTWASFYGGPGELSTTI
EAYVALRLAGDAPDAPHMAQASAWIRERGGIAAARVFTRIWLALFGWWKWDDLPELPPEL
IYFPKWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPHHPNPAKPLARV
ASWDGAFQRLDKALHQYRKVAPRALRRAAMNTAGRWIIERQENDGCWGGIQPPAVYSVIA
LHLLGYDLEHPVMRAGLASLDRFAVWRDDGSRMIEACQSPVWDTCLATIALADAGVPADH
PQLVKAVDWMLGEEIVRPGDWSVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRH
HDPVRVENAIGRGVRWNLGMQSKDGGWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTA
HVVEMLAVEGLSHDPRTRRGIEWLLANQETDGSWFGRWGVNYVYGTGSVVPALVAAGLPG
SHPAIRRAVAWLENVQNEDGGWGEDLRSYDDVPGWSGRGASTASQTGWALLALLAAGENE
SKTVERGVGWLAETQLADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPF
SAKEGG
>A0A523MVS4|squalene-hopene cyclase|EC 5.4.99.17|Nitrospina sp|TrEMBL
MPDQKPEIFENPATAPAATAAPGTPLDRAIGRAKVYLLSLQHADGYWLAELESNATMIAE
YVFFMHFMDIWDPRRVEQCQNTLLKTQQADGGWPLFYGAPSDISTTVESYVALRMAGMSP
KAKAMARARKCIAQLGGVRNARVFTKIFLAMLGQSAWDDLPAMPVEIILLPKSFYFNIYE
MSSWSRGTVVPLTIVAAHQPVWPLKPEHAVPEIFTEADRDLSVQSKRKGLNWPNLFLKID
QLIKFLGKSPVKPFRSWALKRALQWTLDHQEPEGDFSGIQPAMLNSMLAMKLMGYGNDHP
LMVKGYQAIDRFIIDRGDHLIFQACVSPLWDASIACNALMDAGLPGDHPAVVQAGEWMLR
KQVMRPGDWTVKNPNTPPGGWAFEFYNEPYPDCDDTAEILMALDRTGIPDTEWKRKEMQR
AFTWLFSMQSKNGGWAAFDQDNDHELFNRIPFADHGAMLDPPTVDVTGRVLWMLGRINHN
VNDPMVQRALQFIKREQEPDGCWFGRWGVNYIYGTWLVLAGLRSIGEDPSQSYIRKAAEW
LKAHQNKDGGWGETCQSYAEPSLRGKGKSTNSQTAWAVMGLIEADEPHSNAVKRGIEYLV
RNQQEDGSWYEDEFTGTGFPRHFFIKYHLYQIFFPLMALARYRNKT
>A0A4R4UF93|squalene-hopene cyclase|EC 5.4.99.17|Saccharopolyspora aridisoli|TrEMBL
MPSQGAARAEARTAALAARDHLLSLQSPEGWWKGELDTNVTMDVEDLLLRQFLGIRTSSE
TVQTARWIRSQQREDGTWATFHGGPGDLSTTVEAYAALKLAGDDVDAAHMRAARDWILDS
GGLEGTRVFTRIWLALFGEWSWDDLPAMPPEVVLLPEWCPLNVSDWACWARQTVVPLTVV
CTMRPRRDLGIGLRELRTGRPAARPKREWSWGYGFHTLDRVLHRYHRRPVKSLRTHAMRR
AAEWIVARQEADGSWGGIQPPWVYSILALHLLGYPMNHPVIAKGLGGLERFLIREQTPEG
TVRRLEACQSPVWDTVLGVQALRDAGVPADHPSLQRAVDYLLAEEIRVKGDWSVKRPELP
AGGGWAFEFDNDGYPDIDDTAEVLLALNRVEHPDSEAVRGAIARGVRWLRGMRSKDGGWA
AFDADNTRQLVGKLPFCDFGEVIDPPSADVTAHVVEALAVLGEHDEVLRGGVKWLLSNQE
RDGSWFGRWGANHVYGTGAVVPALVAAGVDRQHRALRDAVRWLENHQNDDGGWGEDLRSY
DDPQWIGRGTSTASQTGWALMALLAVGRHDTDAVRRGIGYLARSQRADGNWDEPQFTGTG
FPGDFYINYHLYRVIFPLTALGRYLRDGE
>A0A7W9NKH9|squalene-hopene cyclase|EC 5.4.99.17|Kutzneria kofuensis|TrEMBL
MSDDVIDLARRKAIDHLVSLQDGDGWWKGELETNVTMDAEDMLMRQFLGIREPVGTAETA
NWIRSQQREDGTWATFYGGPGELSTTVEAYTALKLAGDPADADHMVRARQFVLDNGGIEN
SRVFTRIWLAMVGEWSWDRLPVLPPEMILLPKWFPLNIYDWGCWARQTVVPLTIVGSMRP
SRPMGVSVAELRTGRPDKPFEPALSWAGFFQRLDKVLHLHAKLPVKPLREYSIRKGVKWI
LERQEADGGWGGIQPPWVYSILALHLRGYPLDHPVLRKAFDGLESFTIKENGVRRLEACQ
SPVWDTALAVTALLDAGMPPDDPVLKGAGNWLLNEEVTVRGDWAVRRPSLPPGGWAFEFE
NDNYPDVDDTAEIVLALRRMLPADEPAVRRAVEWTIGMQSKDGGWGAFDADNTRRLAEKL
PFCDFGAVIDPPSADVTAHVVEMLAAEGLTGLQPARRGIKWLLDNQEADGSWFGRWGANH
IYGTGAVVPALIAAGIPTVHPAIRRAVKWLEQHQNADGGWGEDLRSYRDKSWIGRGDSTA
SQTAWALLALLAAGERGAATERGIRWLVATQRPDGTWDEPQFTGTGFPGDFYINYHLYRL
VFPLTALGRYLDG
>G2NJQ1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. (strain SirexAA-E / ActE)|TrEMBL
MTATTDGSTGAANLRAVPFGDPIEPTIDTDDVLAAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPATVQAAARFIRGEQLGDGTWNTFHEGPADLSATIEAY
VALRLAGDRPDDPHMIRAAGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMFF
PTWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFTLDELHTDPEQPNPPRPLAPVASW
DGVFQRLDKALHVYHKVAPRRLRRIAMNAAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVMRAGLASLDRFTVWREDGSRMVEACQSPVWDTCLATIALADAGVPSDHPAL
VRAADWMLGEEIVRPGDWSVRRPQLAPGGWAFEFHNDNYPDIDDTAEVALALRRVRHPDQ
PRVDAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGRADDPRTRRGIRWLLDEQEACGAWFGRWGVNYIYGTGSVVPALIAAGLPTGHD
AVRRAVAWLESVQNDDGGWGEDLRSYREEKWIGHGSSTASQTAWALLALLAAGEREGRAV
QRGVTWLAETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFAKGA
GTGPGAASGKGA
>T2AZC4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGHGPDNQAVARAIGYLKRGQEVNGSWYGSWG
>T2AZV6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPFWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGASDVDNEHHSLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGRWG
>T2AZM2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEVNGSWYGRWG
>T2AZF4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGLAMHAVLEANLVPDKIIIEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQPGYGPDNQAVARAIGYLKRVQEVNGSWFGSWG
>T2AZR3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SRVWDTALVSQALIETEYKQHISTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
HSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDVNNTHFYL
NEIPSADHGALLDPPTADVTGRAITLLSLADKKIYAKNIKDGVDYIKSEQEEDGSWFGRW
G
>T2AZK0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPGLSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAIALLSLADKKIYEKNIKDGINYIKSEQEEDGSWYGRW
G
>T2AZE3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRTQKPGLSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTKNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWFGRW
G
>T2AZJ3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PVWDTALVSQALIETEYKQHVSTEIEAALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQY
SNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRSGGFSSFDINNTHFYLN
EIPSADHGALLDPPTVDVTGRAITLLSLADKKIYKKNIKDGVDYIKSEQEEDGSWFGSWG
>T2AZU5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIEIEYKQHVSTEIETALNWLKEQQSSEEPGDWGIQKPELRGGGWAFQ
NSNYYYPDLDDTSMVAWAMHRTNNKSYFEPIQRAANWVAGMQSRGGGFSSFDINNTHFYF
NEIPSADHGASLDPPTVDVTGRAITLLSLADKKIYEKNIKDGVDYIKSEQEEDGSWYGRW
G
>T2AZ72|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGFNGLSLLESGLTLKDSSIQKACKWLEKKRILEIKGDWIVNNKNLLPGGWAFQY
ENDFYPDVDDTAVIVMFLDRAGYQNKKRLEIACNWIIGMQSKNGGWGAFDKDNTYHYLNN
IPFADHGALLDPPTADVSARCISMLSQINKKNYKKIIQKGVKFLKNEQENDGSWYGRWG
>T2AZD6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPAWDTGLSGISLLESGLTLKDISIQKACTWLEKKQILGMKGDWVANNKSLLPGGWAFQY
ENDFYPDVDDTAVVAMFLDRAGYQNKKRLERACNWIIGMQSKNGGWGSFDKDSTYHYLNN
IPFADHGALLDPPTADVSARCVSMFSQINKKNYKNVIQKGVEFLKNEQEEDGS
>T2B0C1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTCIAQLALLESGVAPDDPMVQSSARWLMDKQIFAGGDWQVWAKDTRPGGWSFEFD
NLAYPDIDDASIVVMALERVRLPEAEEPRRADSIKRGVEWVAGMQCKNGGWAAFDKDNNK
KYLTKIPFSDFGETLDPPSVDVTAHLLEMYGRLGYTREEQAVDRGFEYVIGEQEENGSWF
GRWG
>T2AZ10|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
TAFVIQGLLEEGSKKYKSKIIKGMKWLEQKEIKNIRGDWSEKRPKLKSGGWAFQYENPFY
PDLDDTALVGMIFHRQDPKSKNTIIKRTAEWVAGMQSKNGGWGSFDADNTNYYLNHIPFA
DHGALLDPPTADVTARCISFLSQIGYKKNEAITKGINFLKQEQEQNGSWFGGWG
>T2B0E0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
MWDTGLNGLSLLESGLTLKDPAIQKACKWLEKKQILKIKGDWIVKNKNLLPGGWAFQYEN
DFYPDVDDTAVVAMFLDRAGYQNKKSLEKACNWIVGMQSNNGGWGAFDKNNTCYYLNNIP
FADHGALLDPPTADVSARCISMLSQINKNSYKNTIKKGIAFLKNEQEEDGSWFGSWG
>T2AYH3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLNDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSELIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAITLLSLADKKIYAKNIKGGVDYIKSEQEEDGSWF
>T2AZM9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGIACNALMDAGLPKDHPALIKATEFFFRKQVVKRGDWQVKNPNAEPGGWAFEFY
NELYPDNDDTAEILMAIHSIEFPDLRYKLKESQRALSWLLSMQSKNGGWGAFDQDNDQEL
FNAIPFADHNAMLDPPTVDVTSRIIWLLGILGYSREHPQVKKAIVYIISDQENGGSWYGS
WG
>T2AZ95|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDDPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLAPPTVDVTRRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSW
>T2AYF9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGLAAHAVLETLGGNTLLLNKSCDWLSKLQIKEHTGDWGWRRKGLRPGGWAFQYN
NKFYPDVDDTAVVGMALHRQNPEKYTDTISRAEEWIIGMQSSNGGWAAFDADNEYYLLEN
LPFADHRALLDPPTADVTARCISFLTQIGTSNNHPISRGLEFLKRNQEEDGSWYGRWG
>T2B036|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTAIVSIALRESGISEDDPRIRESCDWLIDREIRFRGDWYHKNPVEVEPSGWVFEF
NNKWNPDVDDTAMVLMALRQTPTDNQQRRDESFKRGMEWMKAFQCRDGGWAAFDKDCTKS
ILEKVPFADHNAMLDPECADITARILELLGYEGYPVDDPQVKRGLAYLRSQQETDGSWFG
RWG
>T2B0C4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PMWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELIGGGWAFQY
SNYYYPDLDDTSMVAWAVHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDTNNTHFYLN
EIPSADHGALLDPPTADVTGRAITLLSLADKKIYEKNIKDGVDYIKSEQEEDGSW
>T2AZ16|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLSGIAHLESGLTLKDVAIQKACKWLEKKQILEMKGDWVVNNKNLLPGGWAFQY
ENDFYPDVDDTAVVGTFLDRAGYQNKKRLEKACNWITGMQSKNGGWGSFDKDNTDHYLNN
IPFADHGALLDPPTADVSARCVSMLSQINKKNYKNEIQKGIKFLKSEQEEDGSWYGRWG
>T2AZ61|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINNGVNYIKSEQEEDGSWYGSW
G
>T2AYC4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
MDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDDPGDWRIQKPELSGGGWAFQYSN
YYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYLNEI
PSADHGALLDPPAVDVTGRAIALLSLADKKIYEKNINDGVDYIKSEQEEDGSWYGSWG
>T2AZU3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPGLSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSKPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGRW
G
>A0A7H0NDI8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. CB00271|TrEMBL
MTATTDGSTGAANLSGAPADPTDTTIAADDVTVAARRAAERSVEHLLGRQDEQGWWKGDL
ATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPGDLSATIEAYV
ALRLAGDRPDEPHMARASGWVREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFFP
KWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPDHPNPARKLAPPASWD
GIFQRLDKGLHLYHKVAPRPLRRIAMNLAARWIIERQENDGCWGGIQPPAVYSVIALHLL
GYDLDHPVMKAGLASLDRFAVRREDGARMVEACQSPVWDTCLATIALADAGLRPDHPALV
KAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDPA
RMQAAIDRGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVVE
MLAVEGLAHHPRTREGIAWLLAEQEACGAWFGRWGVNYVYGTGSVVPALITAGLPAGHPA
IRRAVAWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDTRPVA
RGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRAD
AAEEA
>A0A7Y5DST2|squalene-hopene cyclase|EC 5.4.99.17|Methyloglobulus sp|TrEMBL
MFTDANSTTHTQDAQSTSTAIVFKDGQLDLAIKKAQEKLLSLQDKCGYWVFDLEADCTIP
AEYIMMMHYLGEIDGPLQAKIAVYLRSRQSKDGSYPLFTHGLGDISCSVKVYYALKMAGD
SIDAPHMTSLKAWILQQGGAAKANVFTRIALAIFGQLPWRGVPFIPPEIMLFPKWFPFHL
DKVSYWSRTVMVPLFIMCALKATAKNPNNISILELFVTHPDEEQHYFPERTFLNKIFLAL
DKFGRIAEPYIPATIHQRAIDNARDWIIERLNGEDGLGCIFPAMVNAYESLLLLGYPKDH
EYVVTARKAIDKLLVITDDMAFCQPCVSPVWDTALAALALQESDKSNNAKNLTRAYDWLK
SVQLSDEPGDWRVSKPDLAGGGWAFQYANPHYPDVDDTAVVGFAMADSNLPDLDESIHRA
TRWIEGMQSRNGGYGAFDVDNTYYYLNEIPFADHGALLDPPTADVSARCAMLMAKAGKGQ
GLYQAALERSINYLRKEQEADGSWFGRWGSNYIYGTWSVLLGLEQTNVAKTDSMYRNAVK
YLKGVQREDGGWGEDNLSYHDVSYSGKYHFSTAFQTAWAVLGLMAAGEARSSEVKKGIDF
ILRSQQADGVWNDNCFTAPGFPRVFYLKYHGYDKFFPLWALARYRNELKQ
>A0A6B1H3B6|squalene-hopene cyclase|EC 5.4.99.17|Acidimicrobiia bacterium|TrEMBL
MGVEQCLARARDRLLSLQDIEGWWKDELETNVSIEAEDLFLREFLGIADPEVTRQTANWI
RHSQRADGTWATFFQGPADLSVTVEAYWALRYAGDPVDADHMTKAADYIRSEGGLERSRV
FTRIWMALFGLWRWEDLPALPPEVILLPKQVPLNIYDFACWARQTVVSLTVVGAHRPVRS
MGINLDEIRTGATPPEQELAPPGTVARRFQRLDQALHHYENRPHRRLREWSLRRAEQWII
ARQEADGCWGGIQPPWVYSLLALYVRGYSLHHPILAQGLAGFDAWTIVEDDMRRLECCQS
PVWDTCLALIALADAGVDPDDSQMEAGARWLMDQEVQVVGDWAEQRPHLAPGGWAFEFEN
NFYPDLDDTAEVALALRRINHADARKVNRALDRAVEWVQGMQCQDGGWAAFDADNCSPLV
AELPFCDFGEVIDPPSADVTAHVIEMLCELDGDGLGLKVDPVVVDRGVQWLSDEQEDDGS
WYGRWGANYIYGTGAAIPALISAGIPTDDDRVVRACKWLESVQNNDGGWGEDMRSYTSQE
WRGRGESTPSQTAWALLALVAAGRAAEETTRRGVAWLVENQRRDGDWDEPWYTGTGFSGD
FYIRYHLYRLVFPVMALGRWMRAMADES
>A0A502IQ74|squalene-hopene cyclase|EC 5.4.99.17|Brevibacillus laterosporus|TrEMBL
MKEKIELEIKRIIHLLQKAQSADGAWRYCSESGPLTDAYMIILLRTLMIDDEELIRSLAD
RITIRQEKNGAWKLFHDEEEGNLSATIEAYYALLFSGHSRKTDEHMQLAKKFILTKGGIS
EASMLTKILLALTGQYPWPGHFQIPVEIILLPHWFPINFFDFVGYARVHIAPILVVADRK
FVMKTKRTPDMSDLRKNDLPKALGNYPYLTNQRSHEYRALLNTILDGFKNLPYLPSQIHN
MALRQAERFILERIEPDGTLYSYFTSTFLMIFALLSLGYSANHPVITRAISGLKAMTCLT
NGHFHIQIATSTVWNTALLAHAMQATGVSVSEPTVQNAGRYLLSRQHHKYGDWMMKNPFV
LPGGWGFSDINTINPDVDDTTASLRVISKLRETDPTFHHSWDRGLNWLLSMQNADGGWPA
FEKNTDKRIVNWLPFDAADAVSTDPSTADLTGRTLEFLGNSAGFTIGHPQIQRGVEWLLS
NQEANGFWYGRWGISYIYGTWAAATGLIAVGVSSEHPAIQKAVQWLLKIQNEDGGWGESC
KSDIVKTYVSLGVSTPSQTAWGVDALISVFHKPIPAIERGIQFLIDSEKNQDWTLSYPTG
TGLPGGIYFHYHSYRYIWPLLALGNYKKKY
>A0A0B5SD80|squalene-hopene cyclase|EC 5.4.99.17|Bacillus mycoides|TrEMBL
MLLYDKVHEEIERRTTALQTMQRQDGTWQFCFEGALLTDCHMIFLLKLLGRNDEIEPFVK
RLVSLQTNEGTWKLYEDEKGGNLSATIQAYAALLASERYSKEAMNMRRAEMFIKEHGGVS
RAHFMTKFLLAIHGEYEFPALFHFPTPILFLQDDSPLSIFGLSSSARIHLIPMMICMNKR
FRVEKKLLPNLNHIAGGGGQWFREERSPLFQSFLGDVKKVISYPLSLHHKGYEEVERFMK
ERIDENGTLYSYASATFYMIYALLALGHSIQSPIIEKAVTGLKSYIWKMDRGSHLQNSPS
TVWDTALLSYSLQEAKVTNENKMIQRATEYLLQKQQTKKVDWSVHASSLVAGGWGFSDVN
TTIPDIDDTTAALRALARSRGNDRVDDAWGRGVEWVKGLQNNDGGWGAFERGVTSKLLSN
LPIENASDMITDPSTPDITGRVLELFGTYAPNELLEEQKKKAIKWLMDVQEQNGSWYGKW
GICYIYGTWATMTGLRALGVPSTHPALKKAASWLEHLQHEDGGWGESCQSSVEKKFISLP
FSTPSQTAWALDALISYYDQETPIIRKGISYLLAQSTMNEKYPTGTGLPGGFYIRYHSYG
HIYPLLALAHYVKKYRK
>T2AZI6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPGLSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTKNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWFGRW
G
>R9VY71|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAQAVFPLGDTGVPSDDPRMQKAADWLLSKEVRHKGDWAMKVPNTEPGGWYFEFY
NEFYPDVDDTAQVLLALNKVDNPRERYQDQVARRAIDWEFAMQCRNGGWGSFDKDNTKMI
FQYVPFADHNAMLDPPTVDITGRMLEMLAAYGYTRDDKRVQKAIKFILDEQEPDGSWFGR
WGVNYIYGTFLVLRGLDAIGVCHNEPQMQQAAEWIRMVQNSDGGWGE
>R9W216|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAQAVFGLGHAGVRRDDPRLQKAVDWMLAKEVRHKGDWAMKVKNTEPGGWSFEFN
NEFYPDVDDTAQVLLALTKVDNPRERHQYDVAQRAIDWEFAMQCRNGGWGSFDKDNTKMI
FQYVPFADHNAMLDPPTVDITGRMLEMLAAYGYTLEDKRVKKAIHFLLEEQEPDGSWFGR
WGVNYIYGTFLVLRGLDAIGVCHNEPQMLQAAEWIRMVQNADGGWGE
>R9VYT1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAQVLSPVCDHGLPRTDPRLVKAADWLLAKEIRYQGDWSHNVKNIDASCWCFFFN
NDHQPDCDDTAEVLLALKAVDNPRERYQHEDSQRAIDWLFAMQCKNGGWASFDKDNTKKI
FESIPFADHNAMIDPPTVDITGRILEMLASYGYTRRDKRVEKAVQFILQEQEPDGAWFGR
WGVNYLYGTFLVLRGLEAMEFSYLEPAVQQAAEWIRMVQNSDGGWGE
>A0A6N2HPP9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. sk2.1|TrEMBL
MTATTDGSTGAVNPRAASASEPTDTTIAADDVFAAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETVRATGLFIRGEQLGDGTWATFHGGPGELSTTIEAY
VALRLAGDRPDEPHMARASAWIREQGGIAAARVFTRIWLALFGWWRWDDLPELPPELMFF
PKWAPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPANPNPPRRPAPAASW
DGVFQRLDRALHVYHRFAPRGLRRIAMNAASRWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVSPDHPAL
VRAADWMLGEEIVRPGDWSVRRPRLNPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDR
ARVEAAIRRGVRWNVGMQSRNGAWGAFDADNTSAFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGKAGHPATRRGVEWLLAEQEAGGAWFGRWGVNYVYGTGSVVPALVAAGLPVTHP
AIRRAVHWLESVQNDDGGWGEDLRSYHEDEWIGHGASTASQTAWALLALLAAGRRDSGAV
LRGVSWLTGTQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGEPFAVRK
GV
>A0A516RGG3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces spectabilis|TrEMBL
MTATTDGSTGAVTPRAASATDTPDTTPGAAGATEAAKRAVERSTEFLLSRQDPQGWWKGD
LETNVTMDAEDLLLRQFLGIRDEPTTRAAALFIRGEQRDDGTWATFYGGPGELSATIEAY
VALRLAGDAPDEPHMARASAWIRERGGIAAARVFTRIWLALFGWWKWDDLPELPPELLYF
PKWFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDAAVPNPPKSLAPVASW
DGVFQRLDKALHVYHKIAPRKLRKAAMNSAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVLKAGIESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHPQL
VRAADWMLGEQIVRPGDWSVRKPHLTPGGWAFEFHNDNYPDIDDTAEVVLALRRVAHPDR
RRMDSAIARGVHWNLGMQSRNGAWAAFDVDNTSPLPNKLPFCDFGEVIDPPSADVTAHVV
EMLAYEGKSHDPRTRRGIEWLLAEQEANGAWFGRWGVNYVYGTGSVLPALVAAGLPAAHA
AIRRAVAWLESVQNDDGGWGEDLRSYRDERWIGHGASTASQTAWALLALLAAGERDSKAV
ERGVAWLTESQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPSVGGP
GKGS
>A0A522W186|squalene-hopene cyclase|EC 5.4.99.17|Magnetospirillum sp|TrEMBL
MNSLETAVNESAAALMAKQRPDGHWVFQLEADATIPAEYVLYLHYLDERDPEMEKRIGVY
LRDIQGEHGGWPLFHGGDLNISASVKAYYALKAIGDDIDAPHMTKAREAILAAGGAATSN
VFTRTLLALFGQIPWHGVPVMPVEIMLLPKWFPFHLDKVSYWSRTVIVPLIVLMSLRPKA
RNPLGINIAELFTIPPERVSNWYLDEVRSNWAYVFRTLDRVLHKVVHFFPKGLRQRAIDK
AAAFVDERLNGEDGLGAIFPAMVNSVLMYDVLGVPKDDPRVVIAKQSIRNLIVEEGERAW
VQPCLSPIWDTALATHAILEVGGPEAEASARMAADWMVERQITDVVGDWAAQRPGLEPGG
WAFQYANPHYPDVDDTAVVMAALDRIDPQAYEESIRKGAVWLRGMQCKGGGWGAFDAENT
AYYLNHIPFADHGALLDPPTADVSARCVSVLSVLGKRHSDVVAHDGVDYLLREQEADGSW
FGRWGTNYIYGTWSSLAALNAAGLAHGHPAMRKAVQWLESKQRADGGWGEDGRSYWNDQP
RGEATVSTPSQTAWAVLGLMAAGEVGNPAVARGIDYLIRTRNDEGLWDEQHYTAVGFPRV
FYLRYHGYRQFFPVWALARYRNLTTGNAGPVMHAL
>A0A4Y8XUF9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. 4R-3d|TrEMBL
MTATTDGSTGAVGPRAAAASEPSDTTPVATSVAGDIGEVARRATARSVEHLLGQQDAQGW
WKGDLETNVTMDAEDLLLRQFLGVQDARTTEAAGRFIRGEQRADGTWATFYGGPGELSTT
IEGYVALRLAGDRPDDPHMARAAAWIREQGGVAESRVFTRIWLALFGWWKWDDLPEVPPE
LIFLPKWFPLNIYSFGCWARQTIVPLTIVSALRPVRPAPFALDELHTDVSHPNPTKPLAA
AASWDGIFQRIDKALHLYHKVAPRAVRRTAMNAAARWIVERQENDGCWGGIQPPAVYSVI
ALHLLGYDLKHPVMRAGLESLDRFAVWREDGSRMIEACQSPVWDTCLATIALADAGVSPD
HPALVKAAEWMLDEQIVRSGDWAVRRPGLAPGGWAFEFHNDNYPDIDDTAEVILALRRVA
HPDTARMDAAVRRGARWTLGMQSKNGAWGAFDADNVSPFPNRLPFCDFGEVIDPPSADVT
AHVVEMLAYEGLGGHPDTRRGIEWLLAEQEADGAWFGRWGVNYVYGTGSVVPALVAAGIP
VTHPAIRRAVGWVESVQNDDGGWGEDLRSYREEKWIGHGASTASQTAWALLALLAAGRRE
TPAVERGVAWLAAAQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPL
PGRASARAERLGDGRASSVDERRPDSRADSRKGA
>A0A3A9JFN2|squalene-hopene cyclase|EC 5.4.99.17|Roseomonas wenyumeiae|TrEMBL
MNHIATPDLDSLEHDLRRATAALLRQQRPDGHWVFELEADATIPAEYILLRQHLAEPDAP
ELEAKLGRYLRRIQGEHGGWPLFHGGSFDISASVKAYFALKMIGDDPDAPHMARARAAIL
AAGGAARANVFTRILLAQYGQLPWTAVPTTPVELILLPRWFPVHLSRMSYWARTVIVPLL
VLQAMQVRARNPRGIGVPELFTDARLPRKKVKTHHHPGWAAFFNGVDRVLKVAEPIWPRG
SRQRAIQRCVDFVTERLNGEDGLGAIYPAMANSVMMYDALGYPPEHPHRAIARRSVEKLL
VVGEEEAYCQPCVSPVWDTALAAHALMEAGEAEAALRGLEWLKPLQELEVKGDWADQRPD
IRPGGWAFQYRNAHYPDLDDTAVVVMAMDRARRQFGTGTGYDEAIDRGAEWTVGLQSRNG
GWGAFDADNVHHYLNNIPFADHGALLDPPTADVSARCVSMLAQLGEPRGSLRMLNAIDYL
EREQEADGSWFGRWGVNYIYGTWSALCALNAAGFDASRPSLRRGADWLLRIQNADGGWGE
DCDSYKLDYKGYEPAASTASQTAWALLGLMAAGEVDHPAVARGIAWLREHQEEDGLWGQE
AYTGGGFPRVFYLRYHGYPKFFPLWAMARYRNLRQGNSRQVVHGM
>A0A7C2DES7|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MVRRRGSWRRRLASWRRPGAAAGPRPRPTASSASRWAPSRAFASRRGPGASSWSWRGSWA
GGRPEVARTSTVAIRSERGLREAARRARARAVELLLSLQDDGGWWKGELETNVTIEAEDL
LLREFLGIRREEETRLTANWIRRRQRADGTWATFEGGPGDLSTTVEAYVALRLAGDPPEA
EHMRRAAAFVRAQGGLERARVFTHLWLALFGLWPWEDVPALPPELVLLPPRVPLNVYDFA
CWARQTIVALSVVWAHRPVHPLPFDVDELHAGRRADPPPRSIPARAFRRLDRLLHRYERR
PVGPLRRVALARALEWIVRRQEADGSWGGIQPPWVYSLIALRASGYPLDHPVLRRGLEGL
DRFTIVEGELRRIEACQSPVWDTALAVQALADAGLPADHPALVRAADWLLDQQVKVPGDW
AVRRPGLEPGGWAFEFENDTYPDIDDTAEVVLALRRVRHPDPARVDEAVRRAVGWVLGMQ
SSDGGWGAFDADNTRALCREIPFCDFGEVIDPPSADVTAHVVEMLAGEGRASDPAVRRAL
GWLAHHQEPDGSWFGRWGANHVYGTGAVVPAAIAAGIPPPDPRIRAAVRWLERHQGADGG
WGEDLRSYRDPSWIGRGRPTPSQTAWALLALLAAGEGSEAVERGVAWLVETQGPDGGWDE
PLYTGTGFPGDFYINYHLYRLVFPAMALGRYLGRER
>Q63HT1|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia pseudomallei (strain K96243)|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A538M5W9|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MDRDPLAADDGGRRPQRPRGRPRAHEGARRSARVSVATETRLDSAIDAATSRLLELQHPG
GWWVGELESNATMIAQHLFWHHVLGLRTPELDRKIANELRARQRDDGTWSIWFEGPADLS
TSVEAYAALRLAGVDPGEQAREYIRREGGISRTRIFTKCFLALLGQWPWSRIVPIPVELA
LLPPGAPLSIYNFSCWARGTFVPLSVCRALQPVRGADLDLQEIGARPGGSSRPLLSRMKR
VAIREAERWVRDHQEADGSWGGIQPPWVWSILMLASLGHGFEDETLRRAVEGWEGFTIDE
GDRLRPEACQSPVWDTGLAVLALRDSGLAPEHPALARAADWLLAEEVKVKGDWAVRKPDL
APGGWAFEFENDLYPDVDDTTVVALALRRCHRGHEAVERGLAWTAGMQSRSGGWGAFDVD
NEAFWLYKLPFCDFGKVTDEPSADVTAHALEALAPEPGYEREVERGLHWLLEEQEADGSW
FGRWGVNHIYGTAAALPALEACGIDPAHPAFRRAVAWLDSVQNEDGSFGEDIRSYADPAR
RGRGAGTPSQTAWALLAYVAAGEAESTAAGRAADWICTAQRLNGDWEENHYTGTGFPLDF
MIRYHLYRLHFPLLALGRLRERLAR
>A0A538DVI3|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
GRMIDPLVPNAMRAYATRRAEAWVLERLNGEDGLGAIFPAMVNALEALAVLGYASSDPRR
LAAKRALEKLLVVNASSAYCQPCVSPVWDSALASLALQETGGAAALAASVRALDWLQPLQ
LPDDPGDWRVRRPRLAGGGWAFQFSNSHYPDLDDTAVVAWSMHQASNSAHYSHNVQCALD
WLVGMQSRNGGFASFDVDNTHYYLNEIPFADHGALLDPPTSDVTARVVTVLARVGRPQDQ
AALGRAIAFLRAEQEADGSWFGRWGVNHLYGTGAALPALEACGLPQDHPAYRSAVGWLDS
VQQSSGAFGEDVRSYAEPGWRGRGAPTASQTAWALLGYVAAGQSERLSTRRAADYLSRIQ
RPDGDWDEQHFTGTGFPLDFMIRYHLYRLTFPLLALGRLRERLNA
>A0A7X8XLL8|squalene-hopene cyclase|EC 5.4.99.17|Burkholderiales bacterium|TrEMBL
MTHKADSREWLDKGIEKALRWLEQNQTPQGYWAGFMKTNSAIEAEWILAMHFLGIHDDPK
YPEVVRSILSEQRPDGSWEIFHGAPAGDISATVECYAALRAAGLDKDSQPLTKARTWILE
HGGLGKVRVFTRIWLALLGEWPWDATPNLPPELVFLPSWAPLNLYDFASWGRATIVALCL
VSVKRPVRPLPADRRLDELFPHGRKAQDYSLPRPKTPVGWFFFLGDRLLNLYHRSPFQPG
RDMATKLCIEWMVRRQEADGCWAGIQPPWIYALIGLNCHGYALDHPVMKAGLEAFNEPWA
YPTEKGTYLQCCTSPVWDTMLSLLAMTDCGVDCQNPSVQKGLDYLLDQQIDAPGDWQVKV
RGVPSGSWSFEYENDTYPDIDDTAVAMMALARLRDSSADPARVDQALERATLWILGMRSR
NGAWAAFDVNNDSALVSQIPFSDFGESLDPPSADVTAHVIEALGNLGRDMTDPVVARAVD
YLRAEQEDDGSWFGRWGVNYIYGTGLVVPALKAVGENMQADYIQKAADWIVSRQNPDGGW
GETCSSYMDPSLRGVGTSTSSQTGWALLALLAIGDHERDEAIGRGLNYLLETQRPDGTWD
QPEYTGTGFPGYGRGVRTDLKTGQTLDQGKELSRGFMLNYAMYRHYFPLMALGRARRHLE
E
>A0A839NA40|squalene-hopene cyclase|EC 5.4.99.17|Flexivirga oryzae|TrEMBL
MTETLADTSSGGTADVARSTLERAVQRLRDLQLPSGAWKGELETNVTMDAEDMMLRVFLG
IDTEETRDRTACWIRSKQRADGTWATFAGGPGDLATTVEAWIALRMAGDKPNAEHMLLAR
EFIVGAGGLEQTRVFTRIWCALFGWWDWKDLPNMPPELMYLGRRVPLNIYEWGCWARQTI
VPLTVVGTVRPVRPMPWNLDELRTGSTPPRPSGFNIPNAFQQADKVLHLYDKHAIGPVRR
NALRRAAEWIIARQEADGGWGGIQPPWVYSILALHALGYPLEHPVLQAGIAGLDGFTITE
DTPDGPIRRLEACQSPVWDTGLALNALLDAGVDPHDPALRKAGEWLLDEQITTAGDWTVR
RPKLPSGGWAFEYANDVYPDTDDSAIIVMALRRVMTHRGPLQQQAVSHGIAWTAGMQSKD
GGWGAFDADNTSRWPAQLPFCDFGAVTDPPSADVTAHVVEMLAADGRSGGARCKRGVQWL
LDHQEQDGSWFGRWGANHVYGTGAVLPALVAAGVKPDSAPIRAAVRWLADHQNDDGGWGE
DLRSYDDPAWIGRGESTPSQTAWALMALVAAGEFGAPLQRGISHLAETQRPDGGWDERKF
TGTGFPGDFYIAYHLYRLVFPVWALGRAVRALDWHNRGGSRHRERTSGGSS
>A0A4Q2LTS7|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillaceae bacterium|TrEMBL
MSQTLTKIEREITRLTTDLLGKQRQDGAWEFCFENGTNIDAYLIILLRSLDMEDEELIRQ
LHDRILAAQQPEGCWRLFRDEEGGNLSATIEAYYALLYSGYIHKSDEAMERARRYIQSKG
GLGKATSILTKAILAATGQTRWPLAISSIPLEILLLPASFPISFFDFSGYSRVHLVPMMI
MADRRFSVKTERTPDLSGLSSSRTDGNDEQPRGFKEMMDQIEAGMKRLIGVPRHIHEAAT
RKAEAFMLERIEPDGTLYTYASCTIVMIFSLLALGYNKDHPVIRRAVQGIKAMKYRLGDG
RLTIQNSPSTIWDTALLTYALQTSGLPHDHPAIRNAAAYLRGKQQDRSGDWSIHNPDTPP
GGWGFSEPNTIIPDVDDSTAVLRVLASFSRTDPVWRESWNRGLNWVLSMQNKDGGWPAFE
KDTDNHLLTWLAIDGAKSAAIDPSEADLTGRTLEYLGNFTGLDTRYTFIKNGTEWLINHQ
EQDGSWYGRWGICYIYGTWAALTGLIAAGTPARHDAVQKGVNWLLSKQNEDGGWGESCTS
DRLLRYVPLGESTPSQTAWALDALIAALPYPTAQLNKGVNRLIASLQEDDWKTAYPTGAG
LPGSFYFHYHSYRYIWPLLALSHYRRKYGELPK
>A0A5C8TSX8|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium sp. WL103|TrEMBL
MREAVNKVEALQRPKTQAISLDDVDHGVARATRALTALSHDDGHICFELEADATIPSEYI
LFHQFRDTKPPEGLEPKIGNYLRRTQEKHGGWALVHEGPFDMSCTVKAYFALKMIGDDIE
APHMRRAREAILSRGGAAQSNVFTRFILALYGEVPWAAVPVMPVEVMFLPKWFPFHLDKV
SYWARCVMVPLFVLQATKPLAKNPRGIGIGELFLTPPSSVRRWPGSPHATWPWTPIFGGI
DRILQKVEGHFPKRIRLRAMEKARAWVSERLNGEHGLGAIFPAMVNTVLMYEAMGYGPDH
PQVRVACDAIEKLVVVKAHEAYVQPCVSPVWDTALAGHALLEAGGTDAEGQARAGLDWLL
PRQVLDIAGDWAAAKPKVRPGGWAFQYANAHYPDLDDTAVVVMAMDRAMRQHGLVANMPD
YTASIARAREWVEGLQSKDGGWAAFDADNNHMYLNHIPFSDHGALLDPPTADVTARVVSM
LSQLGETRESSKALDRGVTYLLNDQEQDGSWYGRWGMNFIYGTWSVLCALNAAGVDPQSP
EIRRSVEWLIRIQNPDGGWGEDASSYKIDPAFEAGSSTASQTAWALLALMAAGECDDPAV
TRGINFLARTQGADGFWNEERYTATGFPRVFYLRYHGYPKFFPLWAMARYRNLKRGNSRQ
VAYGM
>A0A5J6XNQ5|squalene-hopene cyclase|EC 5.4.99.17|Pradoshia sp. D12|TrEMBL
MTKSNVEKYIASKLERLEKTQNQSGSWTFNFEGSSLTDCFMILLIRTLGIDEEELMHQLV
KRLLRTQNDNGSWSIYPDEKDGNLSATVQSYTALLVSGKFTRMDEEMKRAEQFIIKHGGV
SKSHFMTKMMLAVNGMYNYPSFFKFPMSYFMLPPHVPFNMYQCSNYARVHLTPMTICINK
RFMYEHKGIDKSFLDGQEGGWFREERFFQTEQLINQLKILNFSPSSWQKAGYQSAEKLMI
DRVEKNGTLYSYSSATCYMIYALLALGYKRNSPIILKAMEGMKSYLTDTPYGLHLQNSPS
LVWDTALLSYSLQEAGVKATHPVIDRANAYLLKKQQSTRGDWTVHAPDVIPGGWGFSDSN
HYIPDNDDTSAVLRALTKQSKLNQQANLAWKKGFSYLKGMQNKDGGWGAFEKDAYNSLFA
YLPIENAKDAIIDDSTSDLTGRVLEFMGNYAGLTHDHSFIKRAAAWLLKEQLSDGSWYGK
WGVCYIYGTWAAVTGLCAIGIKPEHPSIQKAIRWLESIQLKDGGWGESCMSADKERYIPL
SYSTPSQTAWALDALLAVKRATSPTIQKGVNFLINEELYHPNANRYPTGLGLRGGFYIIY
ESYNYIFPLLALGHYEKKLITDHT
>A0A554V578|squalene-hopene cyclase|EC 5.4.99.17|Skermania sp. ID1734|TrEMBL
MSQPQLADSDGDTGRAAAARDGDTDRAAAARDRAVEFLRGLQDPEGWWKGELATNVTMDA
EDLLLREFLGIGSPQVLEEASRWIRSQQRADGTWATFEGGPADLSTTVEAWVALRLAGDD
PAEPHMVSAAQFVRRAGGVENSRVFTRIWLSLFGLWSWDEVPSLPPELIYLPKWFPLNIY
DWGCWARQTVVPLTIVSTIRPVHPVSFGIRELHAGSGGARKGGFLPDISISGIFRQIDRG
LHLYSRVPVHPMRGIALRQCAEWIVARQEADGGWGGIQPPWVYSLIALKLMGYPLDHPVM
RAGIDGLDGFTIRESTPQGTVRRLEACQSPVWDTALALYGLLEADLDTDDPMIVRSTDWL
LTQQIDAPGDWCVRRPDVPSGGWAFEFANINYPDTDDTAIVVLALQRLGFRPDCKEAVDR
AVEWVIGMQSRDGGWGAFDADNTRALATKLPFCDFGAVIDPPSADVTAHVVEMLAAVGLA
KDVSCRRGVDWLLRHQEPDGSWFGRWGANHVYGTGAVLPALTASGMAPDAEPIRRAVRWL
VEHQNSDGGWGEDLRSYRDPRWIGVGASTASQTSWALLALLAAREDGPAVQNGIRWLIEQ
QRDDGGWDEDLFTGTGFPGDFYINYHLYRQVFPIWAFNRYLERMQS
>A0A4Z0GR81|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces palmae|TrEMBL
MTATTVEPSETPSEPAALTAARDATARAVEHLLARQDPAGWWKGDLETNVTMDAEDLMLR
QFLGIQDRDTLDAAARYIRSQQRPDGTWATFHGGPPDLSATIEAYTALRLAGDLPDAPHM
AASSAWVRQAGGVARSRVFTRIWLALFGWWRWEDLPELPPEMIYLPSWFPLNIYDFGCWA
RQTIVPLTIVSAKRPVRPAPFALDELHTDPRRPNPPAPGTARTGWDRAFQGLDRALHAYH
KVAIRPLRRAALRSAARWIVERQENDGCWGGIQPPAVYSIIALHLLGYDLDHPVLRAGLE
SLDRFAVWSEERTTGPDGVERTEPVRMVEACQSPVWDTCLATIALADAGLPADHPALVKA
ADWMLAEEITRPGDWTVRRPGLTPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDSGRV
DAAIRRGIRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVVEML
AWEGLAEDPRTRRGIDWLLAEQESDGSWFGRWGTNYVYGTGSVVPALIAAGLPTEHPAIR
RAVSWLERVQNEDGGWGEDQRSYQDSTAWRGRGESTASQTAWALLALLSAGEREGKAVQR
GVGWLVDTQTADGTWDEPYFTGTGFPWDFSINYHLYRQVFPVTALGRYLHGEPSPARARR
P
>A0A3Q9F9X4|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cenocepacia|TrEMBL
MIRRMNQSAPSPWSALDTAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDVRQEKMARYLRANQRLDTHGAWALYVDGAPDVSCSVKAYFALKAAGDSEQAPHMIRA
RDAILKLGGAARSNVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKTRARNPRNVSIRELFVTPPEEERRYFPPARGMRRLFLALDRMVRPIEPL
LPKRLRQRAIRHAQAWCAERMNGEDGLGGIFPPIVYSYQMMQALGYPDDHPLRRDCENAL
EKLLVARPDGSMYCQPCLSPVWDTAWSTMALEQARGVAAPQAGEAAGALRELDARIARAY
DWLAERQVNDLRGDWIENVPADVEPGGWAFQYANPYYPDIDDTALVTAMLDRRGRTHRDA
DGTNPYAPRVARALDWMRGLQSRDGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRADDRASLARAIDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALAGED
TSQPYIARALDWLRARQHADGGWGETNDSYLDPKLAGTNGGESTSNCTAWALLAHMAFGD
CESDSVKRGIAYLQSVQQEDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GAKDAGATTSSASGALVTRATDSALA
>A0A850T1A2|squalene-hopene cyclase|EC 5.4.99.17|Parvularculaceae bacterium|TrEMBL
MYENGAEPANATRGNFEAQLDASIKAAADWLKANQKPEGYWVGRLESNACMEAQWILCLW
FLGLEDHHLRPRLAASLRKTQRADGSWEIYHDAPAGDINTTVEAYAALRSCGVPANDPQL
LRARDWILSKGGLKNVRVFTRYWLALIGEWPWEKTPNIPPEVIHFPNWFIFSIYNFAQWA
RATLMPIAVLSARRPSRPLPPENRLDDLFPGGRANFDYELPGKPGADFWDRFFRTVDVVL
HKMQTFGVRTTLSFGRNGSVKRALEWIIAHQDADGVWGGIQPPWIYSTMALFNEGYAVDH
PVVAKSLAALDDPRWRVDRGDATWIQASTSPVWDTILTLLAFDDCHLNREYPAEIEKALQ
WVLDQQVLRKGDWSVKLPNLEPGGWAFEYKNYFYPDTDDTAVALIALSQFRGDAKWKAKG
IDRAIQRGLNWLIGMQCENGGWGAFDKDNDKKFLTKIPFCDFGEALDPPSVDVTAHVVEA
FGKLGLGLNHPSVARAIDYLKREQEQDGSWFGRWGVNYIYGTGAVLPALAAIGEDMTKPY
VMRAADWLLTRQQENGGWGESCGSYMDPKLSGRGKATASQTAWALMGLIAVNRPADRDAI
ERGIAFLIERQKGGTWEEAEYTGTGFPGYGVGATIKLGDPLLTERLKQGPELSRAFMINY
NLYRHYFPLMAMGRWRAMRESD
>A0A451GBQ2|squalene-hopene cyclase|EC 5.4.99.17|Siminovitchia fortis|TrEMBL
MAYSPNELINRITGILKEEQNCDGSWDYPFDTGVKTDAYMIILLKTLEINDEDLIRRLTE
RILSKQEKNGAWKLYYDEKDGNLSYTVEAYYALLYSGFYPKSDTRLRLAKSFILKNGGME
KAGIFTKVLLALTGQYKWPAFFPLPVELILLPLSFPINFYDFSVFGRANLAPIMILAAKK
YNRKTKDSPDLSDLFVNRTDEFFSADEKRSFENIFSIIEQGIKSILMAPGQLRSYAIERA
KQYMLNHLEPDGTFYSYFSSTFLMIFALMSLGYKKDDPVILKAVEGLKGMECTIQGYTHM
QYTTANVWNTALISYALQNAGVPASDPTVIAANEYLLEKQHYKYGDWVIHNPGALPGGWG
FSDINTFNPDVDDTTAALRAFSPLVTENSALRSSWDRGTNWTISMQNNDGGWPAFEKNVD
KKIMNLLPIEKARFLVSDASSADLTGRTLEFFGNYTNMPKKSEKIRNGAEWLKADQKKDG
SWYGRWGICYIYGTWAAVTGLMAIGFNRKHKSIQNAAAWLKRIQNKDGGWGESCSSDIEN
TYVPLRKSHITQTAWALDALIAAENQPTPEIQAGVRYLLHSYDSENWTWDYPVGQGMGGG
FYIHYHSYRYIFPLLALSNYEKKFKQKIAGT
>A0A7X3ANV1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. Z38|TrEMBL
PPRPLAPATTWDGAFQRLDRGLHKLRRAVPRRLRRAAMNTAARWIIERQENDGCWGGIQP
PAVYSVIALHLLGYDLNHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALA
DAGVPADHPALVKAADWMLGEQVVRPGDWSVRRPHLPPGGWAFEFHNDNYPDIDDTAEVV
LALRRVRHHDPERLDNAVGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVID
PPSADVTAHVVEMLAVEGLAQDPRTRRGVEWLLAEQELDGSWFGRWGVNYIYGTGSVVPA
LTAAGLPTSHPAIRRAVAWLEKVQNDDGGWGEDLRSYSYVKEWSGKGASTASQTAWALMA
LLAAGERDSEAVERGVAWLADTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALG
RYVHGEPFAAKPAEVPAGSAQALADAKGS
>A0A6I6S4N3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. GS7|TrEMBL
MTATTDGSAGAQPPRAPSAGDDTAEKTAPAAKTRGSAKPRAKGKAGKAGRARTAVVQDTA
DAAREATARATDFLLSVQDPAGWWKGDLETNVTMDAEDLLLRQFLGIQDPKLTDASARYI
RGEQRADGTWATFYGGPGELSTTIEAYVALRLAGDDPEAPHMAKASAWVRAHGGIAAARV
FTRIWLALFGWWKWDDLPELPPELIYFPKWFPLSIHAFGCWARQTIVPLTIVSATRPVRP
APFALDELHTDRRRPNPPRPQAPATTWEGVFQRLDKALHVYHKVALRKPRAAAMRSAARW
IVERQENDGCWGGIQPPAVYSVIALHLLGYDLDHPVLRSGLESLDRFAVWREDGARMIEA
CQSPVWDTCLATIALADAGLPADHPQLVRAADWMLAGQIDRPGDWSVRRPQLPSGGWAFE
FHNDNYPDIDDTAEVVLALRRVRHPDPQRVAAAVDRAVRWSAGMQSRNGAWGAFDADNTS
PFPNRLPFCDFGEVIDPPSADVTAHVVEMLADVGRSHDPRTRRGIAWLLAEQEPGGAWFG
RWGTNYVYGTGSVLPALAAAGVPGSHPAVRRAVGWLERVQNEDGGWGEDQRSYQDKEKWA
GRGASTASQTAWALMALLAAGERDGEAVRRGVRWLVEAQLPDGSWDEPYFTGTGFPWDFS
INYHLYRQVFPLTALGRYVNGGPAGVPVGA
>A0A534GLQ0|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MSRKAGTSAALAGTEVLLRADAPARKLPGEKLSPLEYAIAAARDELIRLQRPDGSWELEL
EADCTIPAEYIMMMHFLGELDSALEAKLAAYLRQRQAGYGGWPLYHGGAFDMSCSVKVYF
ALKLAGDDPESPHMARARAAILERGGAASCNVFTRIALALFGQLPWRGVPYIPVEIMLLP
RWFPFNIHRVSYWSRTVMVPLLILCTLKPRARNPHNVGIRELFTTPPEEERRYFRRPLGG
SAALARAFFSLDRLARSLDGLIPRALREHALKRAEAWMLERLNGEDGLGAIFPAMVNALE
ALAVRGYSPDHPHRRGAKRALEKLLVEDYSSAYCRPCVSTVWDTALAGLAMQEEGSAGAR
AAALRGLEWLEPRQLLDDPGDWRTRRPHLPGGGWAFQRANSYYPDLDDTAAVAWSMHRST
DPGRFSFALSRALDWLVGMQSENGGFASFDVDNTSYYLNEIPFADHGALLDPPTSDVTAR
VVTALARVGRPEDRAALTRAIDYLRREQEANGSWFGRWGTNYVYGTWSVLSAFAEARIGP
DDPAVERAVSWLESRQNPDGGWGESNDSYEPGRAGTSAPSTPHQSAWAVLALIAAREAGS
DAVRRGIEYLLRTQRPDGLWSDPSFTAPGFPRVFYLRYHGYCAYFPLWALAAYRNSTAAG
PGTVH
>A0A534B4V1|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MEELDPADYAIGAARDALIGRQSSQGYWLFELEADCTIPAEYILMMHFLGEIDAPLERKI
ATYLRARQGRHGGWPLYHGGDFDMSCSVKAYFALKLAGDSPEAAHMQRARAAILERGGAA
RSNVFTRITLALFGEVPWRGVPYIPVEIMLLPRWFPFHLQKVSYWSRTVMVPLLILCTRK
PVASNPRRVHIRELFTTPPERERHYFRRPGGRADLLAKTFLLLDRLGRLTDPLIPAAVRE
RATRRAEAWMLERLNGEQGLGAIFPAMVNALEALAVLGYRSDDPRRVTAKRALEKLLVVN
ASSAYCQPCFSPVWDTALASLALQETGGPAALAASAKALDWLRSQQLLEQPGDWQARRPG
LAGGGWPFQFANPHYPDLDDTAAVVWSMDQARDPGHYLPNVSRALDWLVGMQSADGGFAS
FDADNTCYYLNEIPFADHGALLDPPTADVTARVVTVLARVGRPGDQAALARAIAYLRAEQ
EADGSWFGRWGTNYIYGTWSVLTAFAHAGVGADDPAVQRAVAWLKERQNADGGWGESNDT
YAQQSSVGGNSPSSPYQSAWALLALLAAGDGRSEAVRRGIEYLWRTQQADGLWSDPSFTA
PGFPRVFYLRYHGYSAYFPLWALAAYRNLARLGTNH
>A0A534E5T6|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
LVEDYSSAYCRPCVSTVWDTALAGLAMQEEGSAGARAAALRGLEWLEPRQLLDDPGDWRT
RRPHLPGGGWAFQRANSYYPDLDDTAAVAWSMHRSTDPGRFSFALSRALDWLVGMQSENG
GFASFDVDNTSYYLNEIPFADHGALLDPPTSDVTARVVTALARVGRPEDRAALTRAIDYL
RREQEANGSWFGRWGTNYVYGTWSVLSAFAAARIGPDDPAVERAVSWLESRQNPDGGWGE
SNDSYEPGRAGTSAPSTPHQSAWAVLALIAAREAGSDAVRRGIEYLLRTQRPDGLWSDPS
FTAPGFPRVFYLRYHGYCAYFPLWALAAYRNSTAAGPGTVH
>A0A6I6KLZ4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces rimosus R6-500|TrEMBL
MTTTADDAPREKGPLPAAEEEAARRAVRRAADHLLSRRHTGGWWEEEFTTDVSYDAHDLF
LRHVLGILDERVATAGGRWIRSQQSADGSWPLVFGGAGHLGTTVQAYVALRLAGHRPDED
HMGRCAAWVREQGGVAAAPLEAHVWLAMCGLWCWDDLPEIPPEIIALPTWAPLNIYAFSS
IMRQALVSLGVISAYRPVQPVPFGIDELFVPSDGTPVRPVSAPITRWAGVFQRANTVLRA
GRRITPRAVRRIATNMCARWLLERQETDGSWGACTPITTWVTLALHLHGYAPDHPVLKAA
LRFLDESASWPEDDMRKLRTVRSPVWDTGLAVTALLDAGLDAGHPALVGAADWLLARQSD
RPGDWTARRPRLAPGGWAFQFHNRTYPDNDDTSEVVLALLRIEHPDRARVDDAVRDAVRW
CLGMQSADGGWAAFDVDNASALPGKLPFFDFGEYCVDAPTADITAHVVEMLAAAGMADDP
RTRRAVQWLLGRQEDDGAWFGRWGVNHVYGTGCVLPALIAAGTPCGHPAVRRAVTWLTSV
QNDDGGWGEDWESYADPGRVGRGPSVPSQTAWALLALLAAGERDSAAVRSGVRWLTGRQT
DDGTWEEPEFTGVLVPRAVACRYGYYRHVFPLMALGRYVHRRDAAATR
>A0A7W7GEW4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces luteogriseus|TrEMBL
MTATTDGSTGALPPRAAAASDTDTHTPGAAGVPEAAAHAARRATDFLLSLQDAEGWWKGD
LETNVTMDAEDLLLRQFLGIRDEKTTQAAALFIRGEQGEDGTWATFYGGPSELSATIEAY
VALRLAGDAPDAPHMAKASAWIRAQGGIAAARVFTRIWLALFGWWKWEDLPELPPELVFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPDLPNPPKPLARPFSW
DGAFQRMDKGLHALRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLEHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLAAIALADAGLPADHPQL
VKAADWMLGEEIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVILALRRIAHPDP
ERLDRAAARGMRWTLGMQSKNGAWAAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIEWLLAEQEPDGSWFGRWGVNYIYGTGSVVPALTAAGIPAAHP
AIRRAVAWLESVQNDDGGWGEDLRSYQHVREWSGRGASTASQTAWALMALLAAGERDSKA
VERGIEWLAATQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGEPFTDM
PRGTGSAEERRVAGKTEQLRGSGTGSPLTEAKGSR
>A0A8B3VD82|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia multivorans|TrEMBL
MNKSALSPWSALDTAIARGRDALARLQQPDGSWCFELESDATITAEYILMMHFMDRIDDA
LQERMARYLRAIQRLDTHGAWDLYVDGAPDVSCSVKAYFALKAAGDSEHAPHMVRARDAI
LKLGGAARSNVFTRILLATFGQVPWRATPFMPIEFVLFPKWVPISMYKVAYWARTTMVPL
LVLCSLKARARNPRNVAIPELFVTPPDQERHYFPPARGMRRAFLILDRVVRHVEPLLPKR
LRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMDVLGYPEDHPLRRDCENALAKLL
VTRPDGSVYCQPCLSPVWDTAWSTMALEQARSVTVPESDESARALDELDARIARAYDWLA
TRQVNDLRGDWIENAPADTQPGGWAFQYANPYYPDIDDSAVVTAMLDRRGRTHRNADGSH
PYAARVARALDWMRALQSRNGGFAAFDADCDRLYLNAIPFADHGALLDPPTEDVSGRVLL
CFGVTRRAEDRASLARAIDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALAGEDPSQP
YIARALEWLRAHQHADGGWGETNDSYLDPALAGTNGGESTSNCTAWALLAQMAFGDCASD
SVKRGIAYLQSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLAGAAE
ARARASSGRAPHAADTALA
>A0A7W1QN30|squalene-hopene cyclase|EC 5.4.99.17|Chthoniobacterales bacterium|TrEMBL
MPGDAPAYAPETSDIREAISRAQRNLLRQQQPDGHWCGELLVDSTLCSDYVLFMHWLGEV
DDTLQQRCVRHILKRQLPDGGWNIYFKGPSEVNASVKAYFALKLAGHSADLPFMQEARAN
ILRLGGIPRMNTFSKLYLALLGQFPWQYLPSIPVEMVLLPAWMPFNIYKMSSWSRAMLVP
LAIINHFKPTRELPGLQQLHELYPLGTEHKDFTLARDARLLTWRNFFLRGDHALKIISKI
GWRPMRQRALEEAERWMLERIGEGSDGLATVFPAMLNALIALKALGYPPTHPAYEKALGD
FRGLFVDDPEDFRIQPCLSPVWDTAINLIALAESGVPAEDPVLRKAAAWLVDKEVHLRGD
WTINNRHPEASGWAFEYNNVYYPDTDDTAMVLTALRLVRPSSAEGLKKLFKRALDWQLSF
QCKDGGWAAFDKEVTQHWLEDMPFADHNAILDPTCSDLTARTLELLGYIGFDRKQPCVRR
AVQYLIDTQDDDGSWYGRWGVNYIYGTWQVLRGLRAIKEDMSQTWILRGRDWLESCQNDD
GGWGETCASYDDPTLKGRGESTASQTSWALMGLCACGDLDRPSVQRGLRYLLSTQRSDGA
WNESEITGTGFPGVFYLKYDMYRQNFPLLALATYVNYRSGIGHRPSFYRCAV
>A0A7S6RVS5|squalene-hopene cyclase|EC 5.4.99.17|Nitrosomonas sp. H1_AOB3|TrEMBL
MSISPTFPGSSLQKSSLSDHSTVSEPFTVVDRVNGISAVALDDAITRARSALLAQQREDG
HWCFSLEADCTIPAEYILMMHFMDEIDTALERRIANFLRNRQVTDGHGGWPLYYGGDFDM
SCSVKVYYALKLAGDSPEAAHMVRARNAILERGGAARSNVFTRLLLAMYRQIPWRGVPFV
PAEIMLLPRWFPFHLSKVAYWSRTVMVPLSILCTLKAKAANPRNIHVRELFTVDPEMEKS
YFPVRTPLNHLLLYLERLGSKLEPLIPSFIRRRALKKAEQWTIERLNGRDGLGAIFPAMV
NAYEALTLLGYDHDHPLLQQCRLALRELLVNEGEDTTWCQPCVSPVWDTVLASLALQEDE
RADSGPVRHALDWLVPLQALDQPGDWRNSRPDLPGGGWAFQYANPHYPDLDDTAAAAWAL
CQADTEDYRTSITRAADWLAGMQSSNGGFAAFDIDNVHYYLNEIPFADHGALLDPPSSDV
TARCIGLLALNGEARHQEAVRRGLAFLFSEQEPSGAWFGRWGTNYVYGTWSVLEALKLAR
VDHDHQAIKRAVQWLKSVQRADGGWGETNDSYLDSELAGQLETSTSFQTAWAVLGLMAAG
EVGSTAVRNGIDYLIRTQSAVGLWEEPWFTAPGFPKVFYLKYHGYSKYFPLWALNRYRAM
NSRSVV
>A0A6N7KUI0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces kaniharaensis|TrEMBL
MGDRPPALLEAGRWRPEDADPPRPGGEADRAAADARDALARATTHLLALQSPEGWWKGDL
ETNVTMDAEDLLLRQFLGIRTEEQTKASAEWIRSQQREDGTWSTFHGGPPELSTTVEAYV
ALKLAGDDPNAPHMLAAARYVRSAGGIAAARVFTRIWLALFGWWPWERLPEMPPEIIFLP
KWLPLNIYAFGCWARQTIVPLTIVSAHRPVRPAPFALTELHTDPDHPFPDRPLAPATTWD
GLFERLDKVLHAYRRRALRPLRRHAIAQARRWIVERQEADGCWGGIQPPAVYSLIALHLE
GYELEHPVMRAGLASFDRFTVHTEDGRRWLEACQSPVWDTCLATIALVDAGVPADHPALV
SAVDWMLGEEIRKRGDWAVRRPSLDPGGWAFEFENDTYPDIDDTAEVVLALCRVAHPDPE
KVGGAVDRGVLWNLGMQSKNGAWGAFDVDNTSTLPNKLPFCDFGEVVDPPSADVTAHVVE
MLAEVGWAGDPRTKRGVEWLLRNQEADGSWFGRWGTNYIYGTGSVLPALVAAGVPDEHPA
IRQAVRWLEDRQNGDGGWGEDMRSYDDPAHWAGRGESTASQTAWALMALLAAGEGPDGRA
NPAVERGVDWLVRTQLPEGTWDEPQFTGTGFPWDFSINYHLYRLVFPVTALGRYLGGRRT
AGRESGAAPAIGAAR
>A0A3N5L0U8|squalene-hopene cyclase|EC 5.4.99.17|Acidobacteriales bacterium|TrEMBL
RQHADGYWWGELTADTTLESDFILLQLWLHPPEGSVWNPPTRALIDKAVRSILARQLPDG
GFNIYAKGPSDVSATVKAYFALKVSGLPADCPELQQARERILALGGIQAANSYVKINLSL
FGLYPRQRCPSIPPEMMLLPGNCIYQMSSWTRAIVVPLAIVHARNPMRPVPANFDLSELF
LPGGGMSYLGGKSPLSWRSLFLAFDRLLKFWEKYGSRALRARAIRKAERWMLERTRYTDG
LGAIYPPMMYIIMALDVLGYPRSHPQFVEALEQFDRLLVDDGERFFFQPCFSVVWDTAIA
AFALAESGMAPADALGRSADWLLTKEVRRKGDWSVKRPDTEPSGWYFEFANEFYPDIDDT
AMVLLALQGAKGVKPQAQEACKQRAIRWLLSMQSRDGGWAAFDVDNNWGLLSEVPFADHN
AMLDPTCPDITGRVLEALCACGLDRNHPAIRRAVDYLIRTQEQDGSWYGRWGVDYVYGTF
LALRGLRAAGEGDREAHILRAGEWLRSVQNGDGGWGESCASYENHAFTPAESTASQTAWA
VLGLLASGDCQSRSVSDGIEYLVETQRRDGSWHEDLATGTGFPMVFYLTYHLYRQSFPLL
ALATYSKMQDADGTERA
>A0A8I1GH59|squalene-hopene cyclase|EC 5.4.99.17|Rhodomicrobium udaipurense|TrEMBL
MNAASSALLSYQREDGHWCFEFEADATIPAEYALLVHYLGEEPNLEREAKIATYLRRIQG
EHGGWPLFHKGEFDMSASVKAYFALKMIGDDIDAPHMVRAREAILSRGGAEMANVFTRIL
LALFGVVTWRAVPVMPVEIMHLPRWFPFHMSKVSYWARTVMVPLFVLGALKPVAKNPRGV
SINELFHTNPKKVGPRPRAEGQSRAWYTFFAGVDACLRVVDPMLPKRSRKSAIGKAVAFV
KERLNGEDGLGAIFPAMANSVMMYEALGVPESDPDRAIARYSIEKLLFETENEVYCQPCV
SPVWDTGLAAHALLETGGEAEREAAHRGLEWLKPLQVLDVKGDWADQKPDVRPGGWAFQY
ANPHYPDVDDTAVVALALDRAAHLPGSNANFEQSVARAKEWVSGLQSKNGGWGAFDADNT
CYYLNNIPFSDHGALLDPPTVDVSARCVSMLAQLGEKPDTNAVMKRGIDYILSEQEKDGS
WFGRWGSNYIYGTWSALCALNAAGLAHDSAAMRRAVAWLVSIQNEDGGWGEDGSSYKLDY
KGYEKSPSTASQTSWALLGLMAAGEVDNPAVKRGIAWLVANQNEAGTWKEERHNAPGFPR
VFYLIYHGYSKYFPLWALARYRNLTSGNRAPVMHGM
>A0A375F1Y9|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus taiwanensis|TrEMBL
MSMHAGAATGAPAQGGCMSMNETALAHAAPQVDSAQREPAGPQQAPATRLSAPALDHGID
RALDALLHQQRPDGHWIYELEADATIPAEYVLMVHYLGEDPDLDLEARLARYLRRIQNPD
GGWPLFHQGRSDVSASVKAYFALKMAGDDPQSAPMQRARQAIRAMGGAEASNVFTRTLLA
LYGVLPWKAVPMMPVEIMLLPRWFPFHLSKVSYWARTVIVPLLVLNSLRPQARNPRGVGI
NELFVGNCHTVGLPPRAAHQHAGWYAVFRGLDALLRVAEPLFPRTLRRRAIAAAQRFVRE
RLNGEDGLGAIFPAMANSVMMFDVLGVPPDDPARAVARRSLERLLVEHGDEAYCQPCLSP
VWDTALATHALLETGDARAAQAAGRALDWLRPLQVLDLRGDWAVRRPLVRPGGWAFQYAN
AYYPDVDDTAVVAAAMDRFMRAHQAPGRYGDAVARATEWIVGMQSGNGGWGAFEPENTHL
YLNNIPFADHGALLDPPSADVSARCLSMLCQTGATPGTSEPAARALRYLLAEQMPDGSWF
GRWGTNYIYGTWSALCALNAAGLPPTAPELQRAVAWLARIQNADGGWGEDGSSYRLDYRG
YEPAPSVASQTAWALLAMMAAGAAQHPAVARGIDYLLRTQQPGGLWHEPRFTAVGFPRVF
YLRYHGYARYFPLWALARYRNLQRGRIGQSGQVSWGL
>A0A8K1MS31|squalene-hopene cyclase|EC 5.4.99.17|Phormidium sp. PBR-2020|TrEMBL
MDRNRFQQAIQASQEYLLQQQHPDGYWWADLESNVTMLAEVILLHKIWQLEDRLPWEKAE
RFFREQQQNHGGWELFRGDGGDLSTSVEAYLGLRLLGVPATDPALVNAKTFILAKGGIGK
TRVFTKMHLALIGAYDWRGVPSIPPWIMLLPREAPFSIYDMSSWARGSTVPLLIVFDEKP
VYRLDPHISLDELYTQGMAAASFELPRTGDWSDAFVELDNLFKWGEQLNLVPFREEGLRA
AEQWVIERQEASGDWGGIIPAMLNSMLALRSLNYDLADPVVERGFEAIARFGVETDNTYW
VQPCVSPVWDTAWVVRSLIESGIAPDDPRIVKGGNWLLSQQILDYGDWQVKNPTGEPGGW
AFEFDNRFYPDLDDSAVVIMALNQTQLPHPEKTQAAVKRGIRWILSMQCQNGGWAAFDVD
NDKDWLNALPYSDLKATIDPPTADVTARILEMAAELETLSPETPLQENSEQFEQALAYLL
GEQEEDGSWFGRWGVNYIYGTSGALSALALVTPERHRGPLERGANWLLSVQNADGGWGET
CLSYDHPRFKGDGDSTASQTAWALLGLMAVAKVLDSGSSPAWREAIARGVDYLMETQQPD
GTWDESWFTGTGFPSHFYLRYDYYRLYFPLLALGRYRQMS
>A0A3P0CAD8|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia anthina|TrEMBL
MNDLTEMATLSAGAVPAGVDAAVARATDALLAAQQPDGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAL
ARKSVEKLLVVHDDEAYCQPCLSPVWDTSLVAHALLETGDARAQEAVLRGLEWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLTQSDTYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGYEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLV
AEQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A6L3AUN1|squalene-hopene cyclase|EC 5.4.99.17|Azospirillum brasilense|TrEMBL
MQDHNASTTLRVQRAEPSAKAVAKAVSDAVAEATDALIRRQQADGHWVFELEADATIPSE
YLLLHHILDEIDPELEAGLAAFIRGRQGKDGGWPLFFGGAMDISCSVKAYFALKAAGDSP
DAPHMRRAREAILARGGAARCNVFTRILLAQFGQIPWRAVPAMPVEVMNLPPWSPFHISR
ISYWSRTVVVPLLVVMAHRLRARNPRGIGIAELFTEPPEEVRNWHSNNSRGGWATLFRAL
DAALHAVEPRLPANGRQTAIDRAVRFVTERLNGEDGLGAIFPAMVNAVLMFHCLGMPPDH
PDAATARRALRGLVVRQPGRVYCQPCLSPVWDTAIICNALLETGSPRARAAARRGADWLI
DRQILDVEGDWAWQRPGLASGGWAFQYNNAHYPDTDDTAMVVMALQRLDTERYGEPIRRA
RDWIVGMQSRNGGWGAFDAENQHDFLNHIPFADHGALLDPPTSDVTARCVMMLARLGEGR
DTVPTRRGLTFLEREQESDGAWFGRWGTNYVYGTWSALEALNAAGVPHAAPAVQRAAQWL
LAHQRADGGWGEDGASYWDGNPRGEGPVSTASQTAWALLGLMAAGKGNHPAVDRGVEYLL
SARDAEGLWSEEPFTAVGFPRVFYLKYHGYAASFPLWALARYRALRV
>A0A3N5HSQ7|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Rokubacteria bacterium|TrEMBL
DDPAMERARERVREMGGPVKANVFTKILLALFGEYDWNGVPAMPAEIMLLPPPFFLFNIY
EVSYWSRCVIVPLLVIMDRKPIKWLPPHQALDELWPIPREQASLRFPRVPEPFSWRGLFW
KSFFIAVDDGLKIWERFSPRPLRKRAIEAARLWLEERLAVPGGLGGIYPAIANSVLALRL
LGYPDDHPLILGQIKELQALAIERDDEFYLQPCFSPVWDTSLVANALIESDLPPNHPALV
RAIDWMLAKQVALPGDWQVKRPHVQPGGWAFQYDNPYYPDLDDTAMVLMALEKVKGVDPD
RTRLARERGLGWFLGMQNQDGGWASFDADNNRIFLNNIPFADHGALLDPSTEDITGRGLE
LLGTLGYGLDFEPADRALDFIRHSQRHDGPWYGRWGVNYIYGTWSVLRGLSAIGVDPRHE
FVQRAVRWLVRRQNADGGWGETAESYSRPELAGRGVSTPSQTAWALLALFAAGHTPGSAV
ARGIAYVRSTQRADGPWEDRYWN
>A0A7Z9M874|squalene-hopene cyclase|EC 5.4.99.17|Rhodospirillales bacterium|TrEMBL
METDTLTVEALDTAIEDALGLLISRQHKDGHWAFELETDATITAEYILLNHFLNEIDNDL
EGKLAVYIRRNQNEDGGWPLYKGGEFNISASVKAYFALKMVGDRVDMPHMRSAREAILAH
GGAVNSNVFTRITLALFRQIPWRAVPVTRIEIMFAPRWFPIHINKVSYWTRTVMVPLLIL
TAQKPAAQNPRGVNIDELFHKPPYRENYKLTNPTGGWVGSLMLVLDRFFRPFEPLIPNLI
TQKAITLGLKFMENRLNDEDGLGGIFPAIANSLMVFDCLGYKNDDPRVVSARKAIDNLLV
IKDDEVYCQPCLSPVWDTGLSAHAVLEASIKKTDDLLDRSSEWLKNLQILDQIGDWAHRR
KNLKPGGWAFQYRNDFYPDVDDTAVVAMALHRQDPKKNAESIKRAEEWIIGMQSSNGGWA
AFDVENEYYLLENMPFADHGALLDPPTSDVTARCVSLLGQIGYGMDHKAISKGFSFLKRE
QEKDGSWYGRWGTNYIYGTWSVLSALNMVGEDMSAPYIRRAVNWLELRQREDGGWGEDCA
TYWEHRKNTAKASMPSQTAWAVLGLMASGEVNSKAVARGVDYLINQNNKNTGWEDKYFNA
VGFPRVFYLKYHGYSLYFPLLALARYRRMKPSNIQSPKFGI
>F2RG17|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)|TrEMBL
MTATTDGSAGAVGPRAAAASTTNDTRAPDLDEAAARATARAVEHLLARQDPEGWWKGDLE
TNVTMDAEDLLLRQFLGIRDEDTTRAAALHIRRQQCEDGAWATFYGGPGELSATVEAYVA
LRLAGDPPEAPHMARASAWVRARGGIAAARVFTRIWLALFGWWRWEDLPELPPELLFLPK
WFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPERPNPPRPLAPATGWDG
LFQRLDKALHAYHRVAPRALRRTAMNLAARWIVERQENDGCWGGIQPPAVYSVIALHLLG
YDLKHPVMRAGLESLDRFAVWREDGSRMIEACQSPVWDTCLATIALADAGLAPDHPALVK
AVDWMLDEEITRTGDWAVRRPELPPGGWAFEFHNDTYPDIDDTAEVLLALRRVRHPDPAR
VDAAVARGMRWTLGMQSKGGAWAAFDADNTSPFPNKLPFCDFGEVIDPPSADVTAHVVEM
LAYEGLAQDPRARRGIDWLLAEQEPNGAWFGRWGVNHVYGTGSVLPALTAAGLPVSHPAV
RRAVGWLGSVQNDDGGWGEDLRSYKEEEWVGRGPSTASQTAWALIALLAAGERDSEPVRR
GVAWLAGTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGEPVPGKVG
>A0A094X7D2|squalene-hopene cyclase|EC 5.4.99.17|Leptospirillum ferriphilum|TrEMBL
MDSRVGNTNPVSTEELQEKVRLAAESLISRQGEEGYWVEPLEADITITSEYVLLQYLLGR
ERDEFFRRAAPFILESQGEDGGWPLYNGGPAEISATVKAYLALKLLGYDADHPAMQRARA
LVLERGGAINVNVFTRITLALFGQYDWKGVPALPPEMILLPRWFPLSIYTVSYWSRTVIV
PLLFIYHYKPLLELPPEKGVQELFITPMSEVRVHYAWDKHWVSWKNLFFVLDRILQAWNR
HPPSFLRRKALKKAMEWMIPRLKGEGGLGAIYPAMANSVLALRLEGYEMDHPLVRRAIQS
IDDLVFDLGEQQSVQPCHSPIWDTALALGALYEAGLDEGSPFVSRALDWFCRKEVRTVGD
WSVRVPGVEAGGWAFQFENDYYPDIDDTSVVLMDFAKWVPEMGAYRDVFRRAIEWTLSMQ
GTDGGWGAFDKDNDFLFLNNIPFADHGALLDPSTSDVTGRVTELLGILGYDARTPVVRRA
LRFLRKEQEENGSWYGRWGVNYIYGTWSVVSALKAVGEDMSAPYVQRAMQFLFSRQNPDG
GWGESCYSYFRKDTAGEGVSTASQTAWALIALIHGGHVRHPAVSKGIDFLLSRQQADGKW
LEQEYTGTGFPKVFYLRYNMYRDYFSLWALSLYRNVLLDGQSRVERLSRRWKGTPYPVRS
RFLA
>A0A6B2T193|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID10115|TrEMBL
MTATTDGSTGAATPRAASASQSTETVLPIDTTAAGPREAAARAMRRSTDFLLARQDAEGW
WKGDLETNVTMDAEDLLLRQFLGIRDEDTTRAAALFIRGEQRDDGTWATFYGGPGELSTT
IEAYVALRLAGDRPDEPHMAKASAWIRDRGGIAEARVFTRIWLALFGWWKWDDLPELPPE
LIYFPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDARVPNPSKPLAC
VASWDGVFQRLDKALHVYHKVAPRPLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVI
ALHLLGYDLEHPVLKAGLASLDRFAVWREDGSRMIEACQSPVWDTCLATIALADAGVPAD
HPQLVKAADWMLGEQIVRPGDWSVRRPGLTPGGWAFEFHNDNYPDIDDTAEVALALRRVA
HPDKARLENAIDRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVT
GHVVEMLAVEGKSHDPRTRRGIEWLLAEQEENGAWFGRWGVNYIYGTGSVVPALITAGLP
ASHPAIRRAVRWVESVQNDDGGWGEDLRSYRDRGWVGHGTSSASQTAWALLALLSAGERE
AKSTERGIAWLVDAQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYINGEPF
AGGSDARTAKGS
>A0A841WTH5|squalene-hopene cyclase|EC 5.4.99.17|Nostoc sp. 2RC|TrEMBL
MQTQDRVKVKQVAQAIAASQEYLLSIQNPAGYWWAELESNVTITAEVVLLHKIWGTDKAR
PLHKVTAYLRQEQREHGGWELFYGDGGELSTSVEAYMALRLLGVPASDPALVRARQFILQ
RGGISKTRIFTKLHLALIGCYNWRGIPSLPPWIMLLPEAFPVNIYEMSSWARSSTVPLLI
VCDRKPIFLADQGINLDELYVEGVERVQWGLPKNNDWTDLFLALDDGFKLAERLNLVPFR
EEGIKAAEKWVLERQEVTGDWGGIIPAMLNSMLALRCLDYDQNDPIVERGLQAIDNFAIE
TKDYYRVQPCISPIWDTAWAIRALVDSGLTADHPAVVRAGEWLLQKQILDYGDWVVKNRQ
GKPGAWAFEFDNRFYPDVDDSAVVVMALHQAKLPNEKIKQAAITRALKWIASMQCKPGGW
AAFDLDNDQDWLNSIPYGDLKAMIDPNTADVTARVVEMLGACNLSIEPHNLQRALTYLLK
EQETEGCWFGRWGVNYIYGTSGVLSALALIGPEKYKLNIERGAAWLLGCQNADGGWGETC
RTYNDPSLKGQGRSTASQTAWALIGLLAAGEATGKLALEAIERGINYLVTTQQPDGTWFE
ADFTGTGFPCHFYLKYHMYQQYFPLIALGRYRRMIDD
>Q1LFR1|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)|TrEMBL
MNQAATITRPQDETLTTSARRPAQPALPDPLDAGIAHVVESLLAQQQSDGHWVYELEADA
TIPAEYILMVHYLGETPDLVLEGKIANYLRRIQNADGGWPLFHAGASDISASVKGYFALK
MAGDNPEAEHMRRARAAIHAMGGAEASNVFTRTLLALYGVMPWQAVPMMPVEIMLLPEWF
PFHLSKVSYWARTVIVPLLVLNSLRPQARNPRKIGIDELFVRPCQATRLPRRAPHQSPLW
VGVFRTLDAVVRMAEPLFPRGLRQRAIERAREFTVERLNGEDGLGAIFPAMVNSVLMFDV
LGVPESDPNRAIARRSIDKLLVIKDDEAYCQPCLSPVWDTSLAAHALLEVGEPRTIAAAA
RGLDWLLPLQELELRGDWTVRRPNVRPGGWAFQYANPHYPDVDDTAVVAAAMDRVDKGDR
SNRYDEAVSRACEWIVGMQSSNGGWGAFEPENTHLYLNNIPFADHGALLDPPTADVSARC
LAMLCQLGQMPANSEPAARALRYLLDEQEADGSWFGRWGTNYIYGTWSALCGLNAAGIGT
DAPEMKRAAQWLLSIQNEDGGWGESGDSYKLEYRGYEKAPSTASQTAWAMLGLMAAGAGD
HPALVRGVEYLLRTQASHGFWDEPYFTAVGFPRVFYLRYHGYSRFFPLWALARFRNLLRD
GNRAISWGL
>A0A3A4NUV3|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Omnitrophica bacterium|TrEMBL
MSHTSYSEIMISTNSALLVETEAGASQRSIDESARQSLENAIPRLLNKQHEKGYWCGELE
GDSILQSEYILLKFIIDQEKDPCLPKIANYLRQQQRPEDGAWIQYPGSRPDLSATVKSYL
ALKLMGDEIDAPHMRKARELILSIGGAEHCNTYSKFYLAALGQMPWDSVPSVPPEMILSP
KWLFFHIDKVSAWTRTMIMPFAIVSHFRPVRRLPDAMGIQELYANPDYYEKPFIGEYNRR
WFTWKNFFLVTDKLIKLWQKSRLLPFRKMALKRIEKWILAHTNSDHADGAGAIFPPMVYN
QIAFRCLGYDPQSPFLTEAARQLDRFMIEEGDTIRLQPCFSPVWDTGIALYALTAAGLDS
NHPAIDQACDWLIKKECRHAGDWIANIREPIEPSGWFFEFNNAFYPDVDDTAMVTMALKQ
AKNGKTKKTLDRAMRWILALQNEDGGWAAFDRTKHRPLLEAIPFADHNAIQDPSCPDITG
RVLECLGHHGFRCDHPMVQKAIRYLQTHQETEGCWFGRWGVNYIYGTWEVLCGLKNVRVN
MQEDWIQKAGQWLNKIQKEDGSFGESANSYEDPSLKGKGPSTASQTAWGAMALMAIYGTE
DPAVESAIQWLIDTQTESGSWNESFFTGTGFPRVFYLRYHLYCLYFPIMAIGRFVRERRQ
FVI
>A0A7S7NJT6|squalene-hopene cyclase|EC 5.4.99.17|Paludibaculum fermentans|TrEMBL
MESAWFESVSRRAGRKSLATIAAHRPALAEACTATLLRAQGALLDLQKPEGYWCGDLLAD
TTLESDYILLQLWLHPPDENGWKPPNRETISKAAQSILERQLPNGGFNIYPSGPADVSAS
VKAYTALKLAGTPAESEAMVNARNCILRLGGIQSANSYVKINLSLFGLFPRQHVPSIPPE
LVLLPGGVLYEMSSWTRAIVVPLSIVQARGGTRPVPPGFDLVELEAPGKSYKLPRKDKLS
LLFSGIDRGLKIWQDRGNTKVKNAAIRAAEKWMLDHTRYCDGLGAIYPSMMYLIMALDAL
GYPTDHPDLKDALAQFDALMTQRGSQFYFQPCFSPVWDTAIATFALGEMGETPPDRMSKA
ADWLIAREVRRKGDWSVKRPDLEPSGWAFEFANEQYPDIDDTAMVLLALMHARGTNPEAQ
ERCARRAVNWLFGMQSRDGGWAAFDVDNDWQLLNRVPFADHNAMLDPTCPDITGRVLEAL
TRRGYSSDNPAIHRGVEYLLKTQERNGSWYGRWGVDYIYGAFLAIRGLRNAHAEGTADAI
KKAARWLAAVQNPDGGWGESCASYVEDHFVAAPSTPSQTAWAVIGLLAAGEGHFEQVRKG
LEYLIQTQKADGTWDEQLATGTGFPNVFYLQYTLYRNYFPVLALSLARKALAGQAAAEKR
LLTM
>A0A7W5E4U8|squalene-hopene cyclase|EC 5.4.99.17|Rhodopirellula rubra|TrEMBL
MIHRLSMTATPFVVAAALSAVPFTHGNLARAESPEQGVAATTEAEQGGNLDRRINVLVDR
GIEFLRTRGQNENGAFSGETGAAVTGLCVRAILEHRPAAVNNDPVVKKSLEFLESKIQPD
GGIYETGSRYRNYETSSAVLALVAASEAAGDAGDGHRKYDSILRRAEMFLKEIQWDEGEG
VTPSDTAYGGAGYGSHSRPDLSNTSFLVEALHELGNDAEDEAIQKALNFVARTQNLSPPE
GAAAGNDTAHGEKIGDGGFYYTPAAGGESKAGEEVNGGLRSYGSMTYAGLKSMIYAGLTP
EDPRVEAALGFIRKNYSLEKNPGMGPQGLFYYYHTFAKALDVAGLEVVDAEGGKVHDWRV
ELVDTLESLQQQDGSWVNRDSDRWMEGDRQLVTAYCLLALSHAKSDASR
>A0A6F7VTF6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. AgN23|TrEMBL
MTATPTVQPSESSESKTLSVAREATARAVEHLLSRQDERGWWKGDLETNVTMDAEDLMLR
QFLGIQDPDTLDAAARFLRSQQGADGTWASFHGGPPELSTTIEAYVALRLAGDEPDAPHM
AAASAWVRSRGGIAAGRVFTRIWLALFGWWRWEDLPELPPEIIYFPKWLPLNIYDFGCWA
RQTIVPLTIVSAKRPVRPAPFPLDELHTDPRRPNPPRPPAPIASWDGAFQRLDRALHAYH
KVAFRPLRRAALRSCARWIVERQENDGCWGGIQPPAVYSVIALHLLGYDLDHPVMRAGLE
SLDRFAVWREDGSRMIEACQSPVWDTCLAAIALADAGLAPDHPALVKAADWMLAEQIDRP
GDWSVRRPGLPSGGWAFEFHNDNYPDIDDTAEVVLALRRVDHPEPERIEAAVRRAMRWTL
GMQSKNGAWGAFDVDNTSPLPNKLPFCDFGEVVDPPSADVTAHVVEMLAHEGRTYDARTR
RGIAWLLSEQEPSGAWFGRWGTNYVYGTGSVVPALIAAGVPASHPAVRRAVRWLESVQNE
DGGWGEDQRSYLDAEWMGRGASTASQTAWALLALLAAGERDGAAVERGVTWLAETQREDG
SWDEPYFTGTGFPWDFSINYHLYRQVFPVTALGRYVHGEPTGARPRSG
>A0A523CM90|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Scalindua sp. AMX11|TrEMBL
MTNLLFDFIEKIDRVSYKFLNGRNGGVVHKVNPKKLCLGKPLEETANSFTCNSKLHTTIK
KAQDHLLKEQDKREGFWVGELEGDAALTAEYIMLMHFIQRVDKKKQEKAAQFLLRTQQED
GGWNIYYKGPGEISVTVKCYFALKLAGHSQEDSFMEKARRCILDLGGITKSNTFTKIYLA
IFGQYDWQGIPALPIEIILFPNSFYFNIYEMSYWSRCIVVPLGIVMAMKPRRNIGGEAAL
DELYVLQKDKVRYRLERDKGIFSFKNIFIMLDSILRRYEKSPYIPLRKLAIEKAEKWLLQ
HFEKSGGLGAIWPAMVNSVMAMKCLGYKDEHPVVKKALIEIEKLEVHDNDSLHMQPCVSP
VWDTPWSILSLSESGLPHDHPALIRAGEWLLEKEVRSFGDWSLKNPVKEPSGWYFQHANE
FYPDNDDTTVVLMALQRIDLPDKARQRDSILRGFKWFLGMQCNDGGWGSFDQNNNKAILN
HIPFADWNALLDPSTSDITARALDVMGRLGYDVNFPPAKKAVDFLKKEQEEDGSWFGRWG
VNYIYGTWSVLSGLYSIKEDMTKEYVKDAASWLKNVQNSDGGWGETCKSYSNTSLKAIGQ
STVSQTSWALLGLLCTEERDSESVEKGIQYLINNQKEDGTWDEEEFTGTGFPQVFYLRYH
MYRSYFPLLALGKYRNMVK
>C4B2M1|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia mallei GB8 horse 4|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANAMRVTVGM
>A0A7W8Z2H7|squalene-hopene cyclase|EC 5.4.99.17|Sphaerisporangium krabiense|TrEMBL
MTTVDVDLPASSAGLALGAACDHLIGLRSPQGWWKGELQTNVTMDAEDLLLREFLGIRGE
QDTAEAARWIRAEQRADGTWANFHGAPPDLSTTVEAYAALRLAGDPPEAPHMRAAAAYVL
RSGGIEATRVFTRVWLALFGLWRWEDLPALPPELVYLPPWFPLNVYDWGCWARQTIVPLT
IVRAHRPVRPLPFGLDELRAGRPVRRKARTGRAAAFAALDHVLRRYERAPFKGARRAALR
RAAEWIVARQEPDGSWGGIQPPWVYSLIALNLSGYDVDHPVMRRGIQGLDRFTIRDGKGR
RLEACQSPVWDTALAVNALLDAGVPADDPVIVQAADWLIGEEVKGPGDWAVRRPGLPPGG
WAFEFDNDGYPDTDDTAEVVLALRRTRRPGGREAVDRGVRWMAGMVSRDGGFAAFDADNT
RELIRRLPFCDFGAVIDPPSADVTAHVVEALAHEGYTRTRLMRRAVVWLLKAQEADGSWF
GRWGANHVYGTGAVVPALVAAGVRPESACVRRAVAWLRDHQNEDGGWGEDLRSYDDPAWI
GRGASTASQTAWALLALLAAGDRSEAVDRGVRWLVETQRPDGTWDEPYFTGTGFPGDFYI
NYHLYRLVFPITALGRYLSARERDGALAAAGGDDHLAAREGDGVLAAREGDGAP
>A8EAV7|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia pseudomallei 406e|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A3N8G054|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp8998|TrEMBL
MIRPMNKPAPSSWSALDTAIARGRDALMRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDARQEKMARYLRAIQRLDTHGGWDLYVDGDPDVSCSVKAYFALKAAGDSEHAPHMVRA
RDAILKLGGAARANVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNIAIPELFVTPPDQERQYFPPARGMRRAFLALDRVVRHVEPL
LPKRLRQRAIRHAEAWCAARMNGEDGLGGIFPPIVYSYQMMDVLGYPDDHPLRRDCENAL
EKLLVTRPDGSVYCQPCLSPVWDTAWSTMALEQARGVAAPEAGAPASEQNELDARIARAY
DWLAERQVNDLRGDWIENAPADTQPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRTHRNA
DGSHPYAARVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRADDRASLARAIDYVKRTQQPDGSWWGRWGTNYIYGTWSVLAGLALADED
PSQPYIARALAWLRARQHADGGWGETNDSYIDPALAGTNAGESTSNFTAWALLAQMAFGD
CESDSVKRGIAYLQSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GARAVPAATATDAALA
>A0A505D7H1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sporangiiformans|TrEMBL
MTATTDGSTGALPPRAASASEIHTTTPTATGAADTRDAAARAIQRATDFLLSTQAPQGWW
KGDLETNVTMDAEDLLLRQFLGIRDEKTTHAAGLFIRGEQREDGTWATFYGGPGELSTTV
EAYVALRLAGDAPDEPHMERAAAWIRDQGGIAAARVFTRIWLALFGWWKWDDLPELPPEL
IYFPKWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDARDPNPVKPLAPV
ASWDGIFQRLDKALHAYRKVAPRRLRKAAMNTAARWIIERQENDGCWGGIQPPAVYSVIA
LHLLGYDLEHPVMRSGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADH
PQLVKAADWMLGEEIGRPGDWAVRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKH
HDPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVTA
HVVEMLAVEGLSHDPRTRRGIEWLLAEQEADGSWFGRWGVNYVYGTGSVVPALTAAGLPG
SHPAIRRAVAWLETVQNDDGGWGEDLRSYRDVAQWSGRGASTASQTAWALLALLAAGERE
SKAVERAITWLAETQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPF
AGRQATESR
>A0A8A7JEJ0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces rimosus subsp. rimosus|TrEMBL
MTATTDGSTGALPPRAPSAGDATAETTENDPAAPTSTAAAARRATARATDYLLSVQDAAG
WWKGDLETNVTMDAEDLLLRQFLGIGDPRTTEAAARHIRGEQRDDGTWATFYGGPGELSA
TIEAYVALRLAGDEPDAAHMARAAAWIREHGGVAAARVFTRIWLALFGWWKWEDLPELPP
ELIWFPKWFPLNIYDFACWARQTIVALTIVCSVRPVRPAPFALDELHADPARPNPPRPLA
PPTTWDGVFQRLDKGLHLYRKVAVRKLRRSALRAAASWIVERQENDGCWGGIQPPAVYSI
MALHLLGYDLGHPVLRQGLESLDRFAVWREDADGAPVRMIEACQSPVWDTCLAAIALADA
GLPADHPQLVKAADWMLAEQIRRPGDWSVRRPRLPSGGWAFEFENDNYPDIDDTAEVVLA
LRRIQHPDPERVDAAVQRAVRWNLGMQSKNGAWGAFDADNTSPFPNRLPFCDFGEVIDPP
SADVTAHVVEMAADLGMTHDARVRRGIRWLLAEQEPDGSWFGRWGTNYIYGTGSVLPALA
AAGIPASHPAVRRAVRWLERVQNEDGGWGEDQRSYHDKAWAGRGESTASQTAWALMALLA
AGERESAAVARGVRWLAGTQRDDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYV
NGGPAGASQGA
>A0A520YW00|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Brocadia sp. BROELEC01|TrEMBL
MRNFLLNLFERLETSIYKFNGNGNGKHPVPELSKDNLLFESLPIQTGFHALSAVKNPLEI
GIHRSQQYLLKSQNPLDGHWVGILEADTTITAEYIMVMHFLGKIDHKKQKMAANLLRDHQ
LSDGGWNIYYGGPSEISASVKAYFALKLAGYTADEPFMQRARKCILEKGGIMKANCFTKI
YLAMFGQVDWQAVPAVPAEMILFPPGFFFSIYEMSYWSRCIVVPLSIAIAKKPHIPVGDD
LLKEIYLIPREKVVYRIKRDQPSLSWRNFFIDADSIFRRYERQPIQCIRRIALRKAEKWM
LDHLEKSGGLGAIWPAIVNSIFAMKCLGYPDDHPALVKQIQEMENLIVYDGDSLYLQPCV
SPVWDTAWAVIALHESGISSADPVLQSAGQWLLSKEIRNFGDWSLKCKVDEPSGWYFQYA
NEFYPDTDDSAAVLMALQRISLPETAHKEAAFLRGIRWLLAMQCDDGGWGAFDRNNNKTI
LNHIPFADFNALLDPSTSDVTARCLDFLGRTGFGKSSQHVRKAIEFLKKEQEKDGSWFGR
WGANYIYGTWSVLSGLSAAGENMNASYIRRAIDWLKNVQNSDGGWGETIQSYDDPFLKAI
GKSTPSQTAWALLGLIVGGEIKSDAVEKGIKFLLAKQKEDGSWDENEFTATGFPKVFYLK
YHMYRNYFPLMALSRYRNLIQNFKSK
>A0A6I5CAT3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID625|TrEMBL
IADEATTRAAALFIRGEQRADGTWATFHGGPGELSTTIEAYVALRLAGDAPDAPHMARAS
AWIRERGGIAAARVFTRIWLALFGWWKWEDLPEMPPELIYFPDWMPLNIYDFGCWARQTI
VPLTIVSAKRPVRPAPFPLDELHTDPLRPNPPRPLAPAASWDGVFQRLDLGLQMFRKVAP
KRLRRAAMNSAVRWIIERQENDGCWGGIQPPAVYSVIALHLMGYDLNHPVMRAGLESLDR
FTVWREDGARMVEACQSPVWDTCLATIALADAGLPADHPQLVKAADWMLGEQIVRPGDWS
VRRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHDPERVDKAIGRGVRWNLGMQS
KNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVVEMLAVEGLAHDPRTRRGIR
WLLDEQEPDGSWFGRWGVNYVYGTGSVVPALTAAGLPGSHPAIRRAVAWLERVQNDDGGW
GEDLRSYHDSTEWSGKGASTASQTAWALMALLAAGERDSKAVERGVRWLADTQREDGSWD
EPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFADRARADRPRAEAQGS
>A0A7X3CX07|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus timonensis|TrEMBL
MAYNIADIRREIHRLSGELIQRQEADGAWRFCFENGITLDACTIILFRTLNADREELIRQ
LHDRILAAQQPEGCWRWYRDDGDGHLSATVEAYYALLFSGFSRPEDEALQRAKRYILERG
GIGQAKSLLTKAILAATGQRAWPSSLSLIPIEILLLPEAFPLNFYDFSGYSRVHLVPLLI
MAERNFRARSVRTPDLSELFSDDRGPEEEALTQSRESREPLEQFQSALGHLVGTPRRIRQ
AAIHKAEQYLLERIESDGTLYTYASCTVLMVFALLALGYETQHKVIQRAVEGLANMKFTV
DGGGLGESGYVTIQNSPSTVWDTALISHALQEAGGPPSHPAVRRAADYLRERQHRKPGDW
QIHNPGTVPGGWGFSETNTFVPDVDDTTAVLRALHALHADDPATLDAWNRGLNWVWSMQN
ADGGWPAFEKNTDKVMLTWLAIEGAKSAATDPSEADLTGRTLEYLGNFAKLGVRHDWVAR
GADWLLSHQQEDGSWYGRWGICYIYGTWAALTGLMAVGMPADHPSIAKSADWLRNIQNAD
GGWGESCRSDQAKRYVPLRASTPSQTAWALDALIAVHDRPTPEIERGSARLIELLHEDGW
PASYPTGAGLPGYFYVHYHSYRYIWPLLALSHYAKKYGDESADDPIG
>A0A1Y0Y100|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter pasteurianus subsp. pasteurianus|TrEMBL
MNMASRFSLKKILRSGSDTQGTNVNTLIQSGTSDIVRQKPAPQVPADLSALKAMGNSLTH
TLSSACEWLMKQQKPDGHWVGSVGSNASMEAEWCLALWFLGLEDHPLRPRLGKALLEMQR
PDGSWGTYYGAGCGDINATVESYAALRSLGYAEDDPAVSKAAAWIISKGGLKNVRVFTRY
WLALIGEWPWEKTPNLPPEIIWFPDNFVFSIYNFAQWARATMMPLAILSARRPSRPLRPQ
DRLDALFPEGRANFDYELPTKEGRDVIADFFRLADKGLHWLQSSFLKRAPSREAAIKYVL
EWIIWHQDADGGWGGIQPPWVYGLMALHGEGYQFHHPVMAKALDALNDPGWRHDKGDASW
IQATNSPVWDTMLSLMALHDANAEERFTPEMDKALDWLLSRQVRVKGDWSVKLPNTEPGG
WAFEYANDRYPDTDDTAVALIALASCRNRPEWQAKGVEEAIGRGVRWLVAMQSSCGGWGA
FDKDNNKSILAKIPFCDFGEALDPPSVDVTAHVLEAFGLLGLPRDLPCIQRGLAYIRKEQ
DPTGPWFGRWGVNYLYGTGAVLPALAALGEDMTQPYISKACDWLINCQQENGGWGESCAS
YMEVSSIGHGTTTPSQTAWALMGLIAANRPQDYKAIAKGCRYLIDLQEEDGSWNEEEFTG
TGFPGYGVGQTIKLDDPAISKRLMQGAELSRAFMLRYDLYRQLFPIIALSRASRLIKIGN
>A0A537Y8F4|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MQLKSHSMAADADALETSIASATSALLGYRQGDGHFVFELEADCTIPAEYVLLRHYLGEP
VDAVLEAKIANYLRRVQGAHGGWPLVHDGALEMSASVKSYFALKMIGDPIDAPHMVRARE
AILAHGGAIHSNVFTRFMLAMFGVMSWRSVPVLPVEIMLLPMWSPFHINKISYWARTTIV
PLMVLAALKPRAKNVSGVGIDELFLQPPHSIGMTAKAPHQSPGWFLLFRALDSVLRVIEP
LFPKKLRARAIDAAVAFIEQRLNGEDGLGAIYPPMANTVMMYEVLGKPADYPPRATTRRA
LDNLLVIREHEAYCQPCVSPVWDTALTCHALIEAGGERALPEAKQGLDWLKPRQVLDLKG
DWAVKSPTTRPGGWAFQYNNAYYPDLDDTAVVVMAMDRERRQSGSNEYDMAIARGREWIE
GMQSRDGGWAAFDVNNLEYYLNNIPFSDHGALLDP
>A0A537TCX1|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MNCVQPKSSAVDQSIEAATRGLFALQQPDGHWVFELEADATIPAEYILLRHYLAEPVDNV
LEAKIAAYLRRVQGEHGGWPLFHEGAFDMSASVKAYFALKMIGDSVDAPHMARARAAIRA
RGGASRSNVFTRVMLALFGFIGWRAVPVMPVEIMLLPKWFPFHLEKVSYWSRTVIVPLLV
LMALQPRARNPRRVALDELFLELPQTIGLAPKAPQQKAAWFWVFRAVDTVLRFAAPRFPR
PLRQRAMQCAVSWVTERLNGEHGLGAIFPAMANSVMMFDALGYADGHPHRAIARRSIEKL
LALRDHEAYCQPCVSPVWDTALACHSLLEVGSDQAVTQVRKGLEWLAAKQILELKGDWIV
RRPDVRPGGWAFQYANPHYPDVDDTAVVVMAMDRAQRLSSQNDFRASIAAAHEWVLGMQS
NNAAWGAFDADNEHYYLNNIPFADHGALLDPPTEDVTARCISMLAQIDESAPNSAAVARA
VDYLRRTQTAEGSWYGRWGMNYIYGTWSVLCALNAAGVDHASPELRRAAAWLVKIQNSDG
GWGEDGMSYRLDYRGHESAPSTASQTAWALLGLMAAGENDHPAVARGIDYLLRTQGEDSF
WNEPRYTATGFPRVFYLRYHGYSKFFPLWALARYRNLKNTNARSVPHGI
>A0A537Q3B8|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MQLKSHSMAADADALETSIASATRALLGYAQADGHFVFELEADCTIPAEYVLLRHYLGEP
VDAVLEAKIANYLRRVQGAHGGWPLVHEGALEMSASVKSYFALKMIGDPIDAPHMVRARE
AILAHGGAIHSNVFTRFMLAMFGVMSWRSVPVLPVEIMLLPMWSPFHINKISYWARTTIV
PLMVLAALKPRAKNVSGVGIDELFLQPPHSIGMTAKAPHQSRGWFLLFRALDSVLRVIEP
LFPKKLRARAIDAAVAFIEQRLNGDDGLGAIYPPMANTVMMYEVLGKPADYPPRAATRRA
LDNLLVIREHEAYCQPCVSPVWDTALTCHALMEAGGERASPEAKQGLDWLKPRQVLDLKG
DWAVKSPTTRPGGWAFQYNNAYYPDLDDTAVVVMAMDRERRQSGSDEYDMAIARGREWIE
GMQSRDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCLAMLAQLGETAETSQA
VARAIEYLRRTQHAEGSWYGRWGMNYIYGTWSVLCALNAAGVSHQDPMIRKAAAWLVSVQ
HKDGGWGEDAVSYRLDYRGMEPAPATASQTAWALLGLMAAGEVENPAVVRGVGYLKATQA
ENGLWDEARFTATGFPRVFYLRYHGYSKFFPLWALARYRNLRSTNSRVVGVGM
>A0A537WGW0|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MTQGMTARAKNQPIVSPALHVPGLNDAIGRAAASLLSLQREDGHWVFELEADATIPAEYI
LLQHYLGTPEPDLERRIARYLQSTQAEHGGWPLFHGGEFDLSATVKAYFALKAAGDPIDA
PHMQRARAAILARGGASRCNVFTRILLALFGEVPWNAVPVMPVEIMLLPSWFPFHIDRIS
YWSRTVLVPLLVLMALRPKARNPNGIRIPELFVEPPETVRHWILPATPSATGYAFTLLDR
IVRLAEPMFPAEPRRRAIEKAVTFVTERLNGEDGLGGIFPAMANSLMMFDCLGYPPDHPD
RVAATAALRKLVVDNGEQAYCQPCLSPIWDTALACHALMEVGETRLTPAVRQALDWLAER
QVLDRVGDWAIARPGLRPGGWAFQYANPHYPDLDDTAAVALALDRFDGAAYEPGIDRAAE
WILGMQSRNGGWASFDADNTHYYLNHIPFADHGALLDPPSADVSARCLGFLAQRGFSPDH
PAVAGALDFLRREQEADGSWFGRWGTNYIYGTWSVLAALNAIGLDPASPEIRRAVVWLLS
YQRADGGWGESGESYWPDKPHGEAPDSTASQTAWALLALMAAGEVAHPAVARGIAYLIES
QDRDGNWNEPWYTAVGFPRVFYLRYHGYRAFFPLFALARYRRLSLANSRRVAFGL
>A0A552A9M5|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa Ma_OC_H_19870700_S124|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPANDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWLGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDPGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKAVDNFAIQ
TDNTYCVQPCVSPVWDTAWVIRALIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKGVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYSDLKAMIDPNTADVTARVLEMLGTCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSAFAFLEPNKYRHQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A7C3WN53|squalene-hopene cyclase|EC 5.4.99.17|Desulfobacca acetoxidans|TrEMBL
MPVEGAVQRAVDALLNLQHPQGYWWAELESNVTITAEYLMLHRLLGLPEHEFPRMAAYLL
GQQLDNGGWSIWYGDGGEISTSVEAYLALKLAGLSSQEAQMVKARDFILSRGGALRTRVF
TRIFMALFGQVSWDGIPLLPVELMLLPPWCGFSIYDFSSWTRATIVPLMIIMARRPVFPV
PPEQGVSELFLSPEEPFERHRVTFKPGGPALENFFVFLDRVLKFFYRRPLGWPHQLALRK
AERWILEHQEESGDWAGIQPAMLNSILALTVLGYDLKHDVIQRGLQALRFFTLQEGNRLW
LQSCISPVWDTALALRALAAAGVPPTHPAMVKATDWLLKQQIRVKGDWSIKNPDLAPGGW
AFEFVNNWYPDIDDSAMVLVALKETLAEPAKYREALHLGVNWVLGMQSRNGGFAAFDTDN
TKEWLNAIPFGDLKALVDPPTEDVTGRALEMMGAFGLGTGHPAAQRALAFIKAKQHPDGP
WWGRWGVNFIYGTWSVLLGLKGLGEDMGQPYIRRAVAWLKAHQNEDGGWGERVESYRQPE
LMGRGPSTPSQTAWAIMALVAAGEAASPEVQAGIRYLVENQNPEGRWDEPYFTGTGFPSH
FMIRYHLYRDCFPLMALGQYVKALKANDRPSG
>G3IWH8|squalene-hopene cyclase|EC 5.4.99.17|Methylobacter tundripaludum (strain ATCC BAA-1195 / DSM 17260 / SV96)|TrEMBL
MFNEANSEINISTVSSSSNTVNSYTDNLNRAISKAQDKLLSLQDKDGYWVFELEADCTIP
SEYIMMMHYLGEIDESLQAKIANYLRPRQSEDGSYPLYTGGPGDISCSVKVYYALKMVGD
SIDAPHMVRLRNYILSQGGAAKANVFTRIALATFEQLPWRGVPYIPVEIMLFPSWFPFHL
DKVSYWSRTVMVPLFILCTLKATAKNPNNINVLELFITHPDEEKHYFPERTLLNKIFLGL
DKLGRLTRPLIPKKAHELAIEKAKNWFIERLNGEDGLGGIFPAMVGSYEAMLLLGMPKDH
HHVVTARKAIDKLLVINEHDAYCQPCLSPVWDTALAALALQEADKAGNSQSLTRAYDWLK
SKQLSDEPGDWRISKPDLAGGGWAFQFENPHYPDVDDTAIVAFAMAESNIPNLDESIHRA
TRWIVGMQSRNGGYGAFDVDNTHYYLNEIPFADHGALLDPPTSDVSARCAMLMARVAQDH
DEYQPALERTIDYIRSEQEQDGSWFGRWGTNYIYGTWSALLGLEQTGLPKTDPMYTKAAT
WLKSVQRGDGGWGEDNYSYHDLSHSGKYHFSTAFQTAWAVLALMAAGEAHSPEVKAGIDF
ILRNQQADGVWNDECFTAPGFPKVFYLKYHGYDKFFPLWALARYRNEFLKK
>A0A7Z2ZTS3|squalene-hopene cyclase|EC 5.4.99.17|Duganella sp. GN2-R2|TrEMBL
MRYSAFHAGAPAGAPAVRGVEDAALRRGGALDRAIERALQAVLDEQRPDGHWVYELEADA
TIPAEYVLMVHFLGEPADPLLEAQIGRYLRRVQGAHGGWPLVHGGAFDPSASVKAYFALK
MIGDAPGAPHMARARAAILLHGGAERSNVFTRMLLALYGVVPWDAVPVMPVEIALLPGWF
PFHLSKVSYWTRTVVAPLLVLGALKPRARNPRAVGIDELFLAPPQQLGQAPRAAHQKRLW
FSFFRVVEAQVRALEPHLPARLRRHAIAQAAAFVRARLNGEHGLGAIFPAMVNAVQMLDA
LGVPPSGPEALQARGAIERLLVRRAGEAYCQPCLSPVWDTALMSHALLEAGTPDAVDAAC
RALDWLLPLQIVDLRGDWSARRPRLAPGGWAFQYENRHYPDVDDTAVVAMALERAGRLRP
QAGYGDAIARARAWIVGMQGRGGGWGAFDIDNDYPYLNNIPFADHGALLDPPTADVSARC
LSLLAQLDGGAGRGWMGRPPRRTPAGRALAWLLRAQERDGSWYGRWGMNYVYGTWSVLCA
LGAAGLGPDAAPVARARGWLASVQNRDGGWGEDARSYEPAQAGFVGAPSTASQTAWAMLG
LMAGAAAGAAPGGVAERAAGGAADGATAAAVARGAAWLIARQRADGLWDEPHHTATGFAR
VFYLRYHGYARYFPLWALARWRNLRAGGAGAAVFGM
>A0A365R2B9|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia reimsis|TrEMBL
MIRRMTQSPLSPWSALDTAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDLRQERMARYLRANQRLDTHGGWALYVDGDPDVSCSVKAYFALKAAGDSEHAPHMVRA
RDAILKLGGAARSNVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNVSIRELFVTPPDEERRYFPPARGMRKLFLALDRTVRHVEPL
MPKGLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMQVLGYPDDHPLRRDCENAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARSVAVPEDGEPDDARRALDARIARAY
DWLAERQVNDLRGDWIENAPADVQPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRTHRNA
DGTNPYATRVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRADERASLARCIEYVKRTQQPDGSWWGRWGTNYIYGTWSVLAGLALAGED
KSQPYIARAIEWLRSRQHADGGWGETNDSYIDPKLGGTNGGESTSNFTAWALLAQMAFGD
CESDSVKRGIAYLQSVQQEDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GAAAAAPAAVDAADTAVV
>A0A840NJ09|squalene-hopene cyclase|EC 5.4.99.17|Saccharopolyspora gloriosae|TrEMBL
MTEQLTRSGVEQQTLPDLPVGGGVRAHAALLAAREHLLSLQDDAGWWKGELQTNVTMDVE
DLLMRQFLGIRTPGETERAARWIRSQQREDGTWANFHGGPGELSTTVEAYTALKLAGDAS
DAEHMITARSWILAHGGIEGTRVFTRIWLALFGEWSWDDLPAMPPEVVLLGKSVPLNLAD
WACWARQTVVPLTVVCTLRPSRELGVSVSELRTGRSAPRPAGAWDRAFHALDAVLHRYQR
RPVKALRELSMRRAAEWIVARQEADGSWGGIQPPWVYSLLALHLLGYPLEHPVLREGLAG
LDGFLIHELTPDGPVRRMEACQSPVWDTVLSVQALRDAGLAADHPALRCAADYLLAEEVR
VTGDWAVRRPNLAPGGWAFEFENDGYPDTDDTAVALLALNRVEHTKPVAVRRALDRGVHW
LRGMQSRDGGWGAFDADNTGTLVTRLPFCDFGEVIDPPSADVTAHVVEALAALGHRDDPV
VRAGVRWLLENQEADGSWFGRWGANHLYGTGAAVPALVEAGLPASHPALRRAARWLEQHQ
NSDGGWGEDMRSYTDARWIGVGTSTASQTGWALMALLAVGAHTGEAVRNGVEFLATTQRP
DGTWDEPHYTGTGFPGDFLINYHLYRLIFPLTALGRYERAVAR
>A0A7W4ZLA1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces violarus|TrEMBL
MTATTDGSTGALPPRAAAASEHDTDIPVAAGVPEAAARATRRATDFLLSRQDAEGWWKGD
LETNVTMDAEDLLLRQFLGIRDEKTTQAAALFIRGEQRDDGAWATFYGGPGELSASIEAY
VALRLAGDAPDAPHMAKASAWIRERGGIAAARVFTRIWLALFGWWKWEDLPELPPELIWF
PKWLPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAAPNPAKPLAPMASW
DGAFQRMDKGLHALRKVAPRRLRRAAMNSAARWIVERQENDGCWGGIQPPAVYSIIALHL
LGYDLQHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLAAIALVDAGLPADHPQL
VKAADWMLGEEIVRPGDWSVKRPALPPGGWAFEFHNDNYPDIDDTAEVILALRRITHHDP
ERIDKAIGRGMRWTLGMQSKNGAWAAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHHPRTRRGIEWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALVAAGIPAAHP
AIRRAVAWLETVQNDDGGWGEDLRSYHDVKEWSGKGASTASQTAWSLMALLAAGERDSKA
VERGVEWLAATQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFADR
HKGS
>A0A0A8K7L7|squalene-hopene cyclase|EC 5.4.99.17|Methyloceanibacter caenitepidi|TrEMBL
MNHWAAQKDLSQAVDLARRHLQDTQAPDGSWHGDYGGPVFLLPTLIVATHIVGEPFDPET
EQDFIRFFKHHQNADGGWPLHIQGESYAYATALCYVAQRLLGVPADDPGLERARVWLLER
GGAANLPPWGKFLLALLNLYDYDGVMPVPPELWLLPTWLPAHPSRFWCHSRMIFLPMSYL
YGIRAQAPLTPVVRALRDEIFCEPYEALDFRGSQMQCAAGDIYAPLSRGYRLLNGLLNGY
EAIAGERLRARATDFVLDQVRQEDENTNNICIGPINKVLNMLCWHFAEPDGKRVAAHRRQ
LPEYLWKGEHGTHMQGYNSSRLWDTAFAVQAICASGRAGTAKPMLELAHAYIEANQVLED
TPDRERYFRDPSQGGWPFSNRTHGWPISDCTAEGLKAAIALRAIVDEPIHDERLDDAAEL
ILGWQNADGGWPTYEKARTPSWMEALNPSLVFADIMVDHSYVECTSACVQALIRYRDQGV
DPARAQCIDKAIARGRDFLLARQRDDGAWMGAWGICFTYGTWFAVSALRAAGLPADSAAL
RRAAAFLVSHQLPDGGWGETIESCRRGTYASTPEGQVVMTSWAVLSLLQTEMADSEPVRA
GLRFLQDRQRADGSWPDEAIAGVFNRTCAITYDNYRKIFGLWALGAADVRVNADMTVQGL
PR
>A0A643FWV5|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus basilensis|TrEMBL
MNARSNAQLNTRLNTQLNAQPGAWQDAGAPTQDTAGTPGADANLHRAIDAAREALLSHQH
RDGHWCFELESDATITAEYILMMHFVDEIDAELQAAMAVYLRSIQRQDRHGGWDQYHGGA
LDVSCSVKAYFALKAAGDDPDAPHMAQARRAILAQGGAAKANVFTRILLATFGQVPWRAT
PFVPVELILFPRWAPVHLDKMAYWARSTLVPLTVLCSLRAKAINPHGVGVSELFVTPPER
ERHYFSREGLMRKAFLVADKLARRIEPWIPAAVRRRAIARAQAWCVERMNGEDGLGGIFP
PMVYWYEMMALLGVPKTDPARVTCLAAIRKLVVRRADGSAYCQPCLSPVWDTAWSIMALQ
HAGTDACTQQAVQRAYDWLEARQVRDLRGDWGKHVPASVQPGGWAFQYANAYYPDIDDSA
VVAAMLAVHARRIGQPERYQDVVASAVKWMVGLQSRNGGFGAFDANCDREYLNRIPFADH
GALLDPPTEDVSGRVLLCIGLSGNREAHAAAVARCVAYLRRTQRADGAWWGRWGSNYIYG
TWSVLAGLALVGEDVRQPYIRKAVDWLLRCQHADGGWGETNDSYFDDALAGTNGGESTPN
CTAWALLALFAVGEVDTPAVRRGIAYLLDCQAVSGLWQHPSHNAPGFPRIYYLKYHGYTA
YFPLWALTRYRQLARRPAAK
>A0A0N1NDR9|squalene-hopene cyclase|EC 5.4.99.17|Actinobacteria bacterium OV450|TrEMBL
MTATTDGAGTPGAEPDDHTPAPGPAPPRVWGAVRIHPGEPAGAAPPRPAAAEPDGPPDAV
RGVPGAQEAAARATRHLLARQDAAGWWKGDLETNVTMDAEDLLLRQFLGIRDEATTQAAA
RFIRGEQAADGTWATFHGGPPELSATVEAYVALRLAGDAPDAPHMARASAWIRAHGGIAA
ARVFTRIWLALFGWWSWDQLPELPPELVFLPPWVPLNIYDFGCWARQTIVPLTVVSAKRP
VRPAPFALDELHTDARNPYPAVRPAPLASWDGVFQRMDRALHVYRRFAPRRLRKAAMNTA
ARWIIERQENDGCWGGIQPPAVYSVIALHLLGYDLGHPVMRAGLESLDRFAVWRDGPPGP
DGRPGGPVRMIEACQSPVWDTCLAAIALADAGLPPDHPALVRAADWMLGEEIVRTGDWAV
RRPGLAPGGWAFEFHNDTYPDIDDTAEVVLALRRIRHPDPARVEAAIARGVSWNLGMQSA
NGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTAHVVEMLAVEGRAADPRTRRGIAW
LLAEQEPTGAWFGRWGTNYVYGTGSVVPALTAAGFDTAHPAIRRAVRWLESVQNEDGGWG
EDQRSYKDPAWAGKGASTPSQTAWALMALLSAGERNGEAVERGIAYLVAAQQEDGSWDEP
YFTGTGFPWDFSINYHLYRQVFPLTALGRYLYGEPFAAGEDR
>A0A0C1V517|squalene-hopene cyclase|EC 5.4.99.17|Methylacidiphilum kamchatkense Kam1|TrEMBL
MHSGRLFLKKENEIGDNKKLRSVPLSLVEETLNFPQKVAETIKKAQRYLLSIQKEDGHWV
GELFVDVTLACDCIHLMHWRGKIDYKKQKRLVKHILDRQLPDGGWNIYPGGPSEVNATVK
AYFALKLAGFSPDEPLMAKARSTILRLGGIPKCMTYTKLGLALLGVYPWDRLPVIPPEII
LFPNWFPFNLYEISAWSRTMLVPLSIIHHFKPTRVLPEKLQLHELFPYGTERGKFSWLKK
GAKYLSKEGLFLACDKFLQYWDKTSLKPFRKMAIEKAEKWMLERIAAGSDGLGAIFPAMH
YAIMALIALGYTEDNPILKKAIADFEALEVDDQKNDDLRIQPCFSPLWDTAVGLVALAES
GYERNAPQLKKAAHWIINREIRIKGDWHVRNPHPEASGWAFEYNNMYYPDVDDTLMVLLA
LRLIDIDDKIKKEEVIQRALRWVISFQCKNGGWAAFDKNVYKKWLEDVPFADHNAILDPP
CSDITARALELFGKMGIRKNEKFVQKAIRYLKETQESDGSWMGRWGVNYIYGTWQALRGL
QAIGEDMTQEWILRARDWLESCQNEDGGWGETPASYDNPQLKGKGPSTASQTAWAVSGIM
ACGDIFRPSVTRGIKYLCERQLSDGSWAEEFLTGTGFPGVFYLKYDMYRNAWPLLVIGEY
YRQYQQAKERATYWVDATLGCMEKRLSAV
>H6CKD8|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus sp. Aloe-11|TrEMBL
MELLEKVQAEINRYMTRIQSEQQEDGSWRYDFETGPMTDASMMILISSLYPEEQELLSKL
AQRLVYKQADGGEWKQYDDDDGHLSSTIEAYTALLLSGYLERDAPPMKRAKDYILRSGGV
EKAHVSTKFMLALNDLYPWPAYYPMPLFLIHLPKWIPFSFYRWSSYVRTHFAPILILVHL
KFTLPHPSGADISHLYTTPKYNKLHHQSHGRRRSVKGKRSNRSIQKAESFIFEHIEGDGT
LHSYASATFFMIYALLAIGYQPDSPVISRAMKGLLSFVTKTDDGGMHIQNSPSTVWDTAL
ASYTLQEAGLSAGDHTVQRAAAFLLSLQHTEKKAQAEGSLLHMTGGWGFSESNKANPDVD
DTQAVLRALTRYTSYHADSLESWRKGVQYLFRRQNDDGGWAAFERNSTSFMTRLFAVENF
EDTAFDPSAADVTGRTLEFLGNHVKLTTNHPRVQAGVRWLLKRQQRDGSWYGRWGVSYLY
GTWAAVTGLRAVGLSAEHPAIQQAADWLLRMRQPDGGWGESCKSDVAKTYIAAPYSTVVH
TAWALDLLIAVHDTPVKEIKEATSLLIDWNREEGSKRVTYPTGAGLPGHFYIQYHSYPRI
WPLLTLSHYEQKYKDC
>A0A1L3RE57|squalene-hopene cyclase|EC 5.4.99.17|Granulibacter bethesdensis|TrEMBL
MPKDIPADLASEAISGDMLEQAVLRASMALHRKQQTDGHWVFELEADATIPAEYVLLEHF
LDRIDTDLEHKIGVYLRRIQGDHGGWPLFHEGAFNLSASVKAYYALKAIGDNPDAPHMRR
AREAILAAGGAERSNVFTRIQLALFGQIPWRGVPVMPAELMIAPKWFPINMWKVSYWSRT
VIAPLLVLMDRKPQARNPRNVHVRELFLNDPEHIRDWIRGPFRSGWGYVFKYLDSILRVV
EPVALKPLRPRSIRLAVDFVRERLNGEDGLGAIYPAMANSVMMYDVLGYSPDHPEAAIAW
ESVRKLLVIKDDEAYCQPCLSPIWDTGLSGHAMAEAEGAISPGVAAACDWLRNRQITDVV
GDWAEIRPGVQPGGWAFQYNNAHYPDVDDTAVVAMLLHRQGDPAHEESIRKARHWIIGLQ
CRDGGWGAFDADNDKDYLNHIPFADHGALLDPPTADVTARCISFLAQLGNPEDKPVIDRA
MAWLRKEQEADGSWFGRWGTNYIYGTWSVLCAMNAAGVPHDDPAIRRAVNFLLATQREDG
GWGEDEETYDPASGAQPGRYKESTPSQTAWALIGLMAAGEAEHEATQRGIAYLQATQKPD
GEWDEAAYTAVGFPRVFYLKYHGYRQFFPLLALSRYKNLRSSNTKKVSFGF
>A0A5Q4ZPY4|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia dioscoreae|TrEMBL
MNDLSQTQPLDAVLPEVAGAVPPAPAAASEAPAALLDAAITRATDAILAAQKPDGHWVYE
LEADATIPAEYVLLVHYLGETPNVELEQKIARYLRRIQLPDGGWPLFTDGALDVSASVKA
YFALKMIGDPADAEHMVRAREAILANGGAEAVNVFTRILLALFGVVSWRAVPMMPVEIML
LPMWFPFHLSKVSYWARTVIVPLLVLNAKRPLARNPRRVRIDELFRGAPVNTGPRDRAPH
QHAGWFRFFSGVDMLLRAVDGLFPKATRERAVRAAVAFVDERLNGEDGLGAIFPAMANSV
MMYDVLGYPADHPNRAIARQSVEKLLVIKDDEAYCQPCLSPVWDTSLVAHALLETGEAHA
EQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYNNDYYPDVDDTAVVVMAMHRS
AALTHSEVDREAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTAD
VSGRCLSMLAQLGELPQGSEPAQRAFAYMLKEQESDGSWYGRWGLNYIYGTWTALCSLNA
AGMPHDDPRMKRAAQWLLSIQNEDGGWGEGGESYKLDYQGYERAPSTASQTAWALMGLMA
AGEVNHEAVARGVAYLQREQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARFR
HLKRNGLTRVAVGM
>A0A4Q9I0X0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces kasugaensis|TrEMBL
MKATTDGSTGAPAPRAPSASDDAAETTAYTPTVVAGDTMAAARHATTRATEHLLAAQDSA
GWWKGTLETNVTMDAEDLLLRQFLGIQDRGTTEAAARHIRAEQRADNTWATFHEGPGDLS
ATIEAYVALRLAGDAPDAPHMAGAAAWIRGHGGIAAARVFTRIWLALFGWWRWEDLPELP
PELIYFPQWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPRHPRPRQPL
APAASWDGLFQRLDKALHLYHKVALRKLRGAAMRSAARWIVERQENDGCWGGIQPPAVYS
IIALHLLGYDLDHPVLSAGLRSLDRFAVWQEDGSRMIEACQSPVWDTCLATIALADAGVP
ADHPQLVKAVDWMLAEEIDRPGDWAVRRPQLQPGGWAFEFENDNYPDIDDTAEVVLALRR
VRHPDPARVDAAVQRAVRWNLGMQSKNGAWAAFDADNTSPFPNRLPFCDFGEVIDPPSAD
VTAHVIEMLADVDRTHDPRTRRGIQWLLAEQEPSGAWFGRWGTNYLYGTGSVLPALAAAG
IPGSHPAVRRAVGWLERVQNDDGGWGEDQRSYQDKKWAGRGASTASQTGWALMALLAAGE
RDSEAVRRGVRWLADTQRADGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGG
PAGASLGA
>A0A525JJX4|squalene-hopene cyclase|EC 5.4.99.17|Phenylobacterium sp|TrEMBL
MNDISAGLSPPITVLDRRIRRAAEALLKRQQPDGHWVFELEADATIPAEYILLRQFLNEP
DDLELERRIGVYLRRIQGAHHGWPLVHGGPFDVSASIKAYYALKMIGDDPEAPHMAAARA
AIRAHGGPNAANVFTRIQLALFGQMSWARIPTMPIELILLPRWFPIHLSKMSYWARTVIV
PLLVLQTRKPVARNPRGVGIAELYEGAADIRPASKAAATKRIWTVGFNALDVVLKAAEGL
WPRRLRARATQACVDFVTERLNGVDGLGAIYPAMANSVMMFDTLGYPADHPNRAMARESV
ERLLVVKDDEVYCQPCVSPVWDTALTCHTLLEVGGEAGEAAAAQGLDWLIPRQVLDVKGD
WAEQKPDVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRARPRSGARFDEAIARGTEWVEGL
QSRDGGWGAFDADNSFHYLNNIPFADHGALLDPPTDDVTARCISMLAQLGKDRGDPQVKA
ALDFLATSQMADGSWFGRWGVNYVYGTWSVLCALNAVGLTAEDPMVRRAADWLVAIQNAD
GGWGEDCESYALDYKGHQPAPSAASQTAWALMGLMAAGLVDHPAVARGVAWLTSVEDAEG
FWPEAGYTGGGFPRVFYLRYHGYSKFFPLWALARYRNLTQANSRQVGFGM
>A0A536XD15|squalene-hopene cyclase|EC 5.4.99.17|Betaproteobacteria bacterium|TrEMBL
MDGLSSRKSPLMPGRGRTARLPPAELLQSSLERCIEKAMTALLHRQRQDGHWVFELEADA
TISAEYVLLQHFLGESDTSIETKIAAYLRGLQGTHGGWPLFHGGDFNLSASVKAYFALKI
IGDSPDAAHMRRAREAILAHGGAGETNVFTRILMALFGVISWRSVPTIPVEIVFLRRWAP
FHLSRISYWSRTVLVPLLVLQALKPRACNPRGVHIDELFAHGIPRARRWVRAAHQSRLRF
ALFAALDAVLRLIEPLIPGTLRRNAIARAVDFVSERLNGEDGLGAIFPAMANAVMMFHAL
GYPRDHPDLATARKAIDKLLVLSHNRAYCQPCVSPVWDTVLACLSLLETDTDRARNAVRD
GLVWLSKRQVLDTTGDWAEQRPHVRPGGWAFQYANPHYPDLDDTAAVVMAMDRFARGGNG
RAEPDFGSCIERGRDWVLGLQSVNGGWGAFDADNTSEYLNHIPFADHGALLDPPTADVSA
RCAGMIAQLGRAEDAPALARALEFLRRSQEGDGSFYGRWGMNYLYGTWSALCAFHAAGVN
PAAAEVDKAVAWLNSCQNDDGGWGETGDSYSLDYRSPRRSTSTASQTAWALLGLMAAGDV
RSAAVARGVDYLIRRQGRDGFWTEPQFTATGFPRVFYLRYHGYPKFFPLWALARYHRLIQ
LRGPEPRFGI
>A0A7Y9JKZ8|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura luteofluorescens|TrEMBL
MTTTEPTTTGTTPAPEPPAAGGTARIRTAAEALAAARDHLLLLQSPEGWWKGELQTNVTM
DAEDLLLREFLGIRDDADTAEAARWIRSQQAADGTWANFHDGPPDLSTTVEAYVALRLAG
DPPDADHMVRAAAFVRGGGGIPATRVFTRFWLAMFGRWPWERLPVLPPEMMFLPRWFPLN
VYDFACWARQTVVPLTVVASLRPVRPLPFTLDELYPGYDVPPARRRGFSGWDAAFGALDA
ALHVYERHPAKGVRRAALRRAADWIIARQERDGSWGGIQPPWVYSLLALHLLGYGLDHPI
VRRGLDGLERFTIRDDRGRRLEACQSPVWDTALAMNALADAGLPAGHPALERAAEWLIGE
EVRGPGDWSVRRPDLPPGGWSFEFDNDCYPDTDDTAEVVLALGRARHPLAEPAIERGVRW
MAGMASRDGGFAAFDADNTRALCRRLPFCDFGEVIDPPSADVTAHVVEAMAHRGMADSQV
VKRAVVWLLKAQEPDGSWFGRWGANHVYGTGSVVPALIAAGVRPGRPAIRDAVAWLERHQ
RDDGGWGEDLRSYRDRTWIGHGASTPSQTAWALLALLAAGERGPAVERGVRWLVEHQRPD
GTWDEDHFTGTGFPGDFYINYHLYRLVFPLSALGRYLKETS
>A0A4Q2RGB2|squalene-hopene cyclase|EC 5.4.99.17|Lichenibacterium ramalinae|TrEMBL
MSLAAQAAAPVGRTSLFDVTGLDAAITRAMSALLEEQRADGHYAFDLEADAAIPAEYIMV
KHFLGEVEPEMERRTANYLRRIQESHGGWPMLAKGQLNMSASVKAYFALKIAGDPVDAPH
MVKARNAILAHGGAVNMNIFTRMMLAFFGIVPWSAVPVMPVELMHAPGWFPINIWRFSYW
ARDTVVPLLVLMAKKPRAANPRRVGIDELFIVPPHAVKRWPKTVNQVGFWGAFFVGLDKV
LRVTEPLFPKKSRDSAIQKAVEFLRERLNGEDGVGAIYPSIAYTVMMFHVLGVPEDHPDM
IIAKKALEKLVAHNGDEAFCQPCLSPVWDTVLTAHALLEAAPDDTASAERALDWLLPLQV
LDVKGDWAYRRPDLRPGGWAFQYKNDHYVDLDDTAVVVMAMDRARNKTGTRRFDHAIDRA
VEWVVGMQSTNGGWGAFDVDNTSYYLNHIPFADHGALLDPPTADVTARCLSMLGQLGETA
KTSEAVRRGVDYLLREQHPEGSWFGRWGINYIYGTWSVLCAFNAVGIDAGHPAVRRAVDW
LIAIQNPDGGWGEADAGYALDYVAYKPSETTASQTAWAVIGLMAAGEVDHPVVKRGIAYL
EQNQGEDGFWQEPHYTGTGFPRVFYLRYLGYAKFFPLWALARYRSLKQGNTAAVLHGM
>A0A6G4WTI1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces boncukensis|TrEMBL
MTATTDGTAGSGLSGTEHTDREPPGTDAPGPESLTALAERTTARAVDHLLGRQCDEGWWK
GDLETNVTMDAEDLLLREFLGIRDERLLRAAARFIRAQQRKDGTWATFHGGPGDLSATVE
AYVALRLAGDEPEAPHMALASAWVRERGGVAGARVFTRIWLALFGWWRWDDLPEMPPELI
YLPKWFPLNIYDFGCWARQTIVPLTVVSALRPVQPAPFRLDELHRDPARPSPPTAVQLPT
SWDGAFQWLDRGLRAYRKVAVGPLRRAALKDASRWIIERQENDGCWGGIQPPAVYSLIAL
KLLGYDLDHPVMRAGLESLDRFAVWPDEETRMVEACQSPVWDTCLVSIALADAGLPGDHP
ALVKAADWMLSEQIVRPGDWSVRRPQLPPGGWAFEFHNDNYPDIDDTAEVALALRRVEHP
EPERVDSAVRRAVRWNLGMQSNDGAWGAFDVDNTSKFPNLLPFCDFGEVIDPPSADVTAH
VLEMLAAEGKQAEPRARKAISWLLAEQESNGAWFGRWGVNYLYGTGAVVPALVAAGIPAS
HPAVRRAVSWVESVQNDDGGWGEDLRSYIDADWVANGTSTPSQTGWALMALLAAGERDSK
AVERGVVWLAEQQREDGYWDEPFFTGTGFPWDFSINYHLYRMVFPLTALGRYLHGDGLGH
LAARSA
>A0A3L7RWY5|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
KGCDAIGFRPLRSRAVAECRRWMLERFDGSDGLGAIFPPILWSIVALRAFGCPDDAPEVR
ECWRQLEGLIEHEADGTTRIEPCRSPVWDTALTLRALAVDRLARRAVVHSGDSDQALDDA
VDWLLSQEIRTDGDWSRRTVPVAPSGWCFEYANRFYPDVDDTAMVLIALATWREGERSDD
AASQRRRSLVEAAIDRARPWLEALQNSDGGWGAFDKDNNCEILCKVPFADHNAMIDPSSP
DLAGRVLEAFGRIGYRLGHPAVDRAVAYLRRSQEEDGAWYGRWGVNYIYGAWQAIEGLRA
VGVPADDPAVAAAARWLLSHQQPCGGWGESADSYADPSLAGQGEPTPSQTAWALAGLLAS
GHAGSPEARRGVTWLVDHQTPDGDWAEENFTGTGFPKVFYLRYHWYRVYFPLMALGRWSI
ARGTGDADGAPSDENIHSARRAGQVREKVA
>A0A3L7UZH9|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MPNLPILSESALSCEQDRLSSELDVTIDAVNDWLLAQQKSDGHWCAELEGDTILESEYIL
MMAFLGRHRSQECVRSAKYMLTLQNSEGGWAIYPGGPTELSATVKAYYALKLAGFSIDDP
RMVKARELILASGGAMRCNSFTRFYLALLGQIPYGDTPCVPPEIIFLSHRLPFSIWAMSA
WTRDMVVALSIISALKPCRKLQGDEAIDELFVAGVRSTPDLGKRMLSWKRFFYVMDKGLK
VYEKVAPKFVRGRAVNACKRWMLEHMENSDGFGAIFPPMVYTVIALKALGYSDEHNLQQW
ALSKLEELLIEENGLIRIQPCFSPVWDTAIAAIGLTDGGLPGDHPAMKKATRWLLDKEIR
VKGDWQLRGPKHVEPTGWHFQYANQFYADIDDTAMVLLALQRGPGSDSDEIRAATSRGVA
WLLEMQNRDGGWAAFDIDIDNEVLTQVPFADHNAMLDPSCVDITLRIVELLGVMGYDRHH
PKIAKALDYLWKTQEPEGCWFGRWGVNYIYGTWQALQGLHAIGYPMGDQRVQKAAEWLKS
VQQPCGGWGETCASYDDASLKGTGKATASQTAWALLGLISAGEQGSEAVVRGVRWLVSEQ
NKDGIWDEPEFTGTGFPKVFYLKYHYYRAYFPLMALGRYRKALAGLSEQEKTEGAFREGS
RQVASPHFNSHA
>A0A538RWY9|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MNGSPIVFAHRVSTSSGARSASTHPTILSAAVDHACNCLLDRQAPDGHWVGELQGDTILE
SEYILLMAFLGREGEERVAKAGRYLLTQQMPEGGRNNYPDGPSDLSVSVKTYFALKLAGH
DAQAPYMRRARTIIRGLGGAAKCNSFTQFYLALLGQFPYANCPAVPPEIMLLPRWAYFNI
YAMSSWTRTIVIPLSIFYAHKPVRRLPPGMDIGELFLEPPDTPQWPHPPTRRWLSWTNLF
LVLDQLIKRLDPGDVKVARRLEAEGTHARGRSFWRRPLAWLRKRALDRAAAWLLEHFEDS
DGVGAIYPPIIYTIVSLRCLGYADDSTEMRWALQQLDDLMIEEPDTLRLQPCFSPVWDTA
LSLIALADAGLSGSHQAVLRGVDWLIERQARRPGDWSTMNPGLEPGGWFFEYRNGFYPDT
DDTAMVLTALAKTGQAASGAGRAAAQRGLRWLLGMQNRDGGWAAFDRDINREVLTKVPFA
DHNAMLDPSCPDITARVLEALGYHGYGLDLAQVQRAIAFLRARQEPSGAWLGRWGVNYIY
GTWQVLTGLRSIGFDMADPMVRRAAAWLKQVQQSCGGWGETCRSYDDPSLAGQGTPTASQ
TAWALLALLAAGEEHSKTVRAGIDYLLATQQPDGGWHEDHFTGTGFPKVFYLKYHMYALY
FPLMAVARYAAAL
>A0A7W7TUK8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces nymphaeiformis|TrEMBL
MTHCALPLPGVSLAVPGPRPEPLPGTGPLDRARARLATRLVAAAGPDGLLRAPCDSRILE
SALALRLLTVTGVDPDAQERLTRRLKTAVDEGAPDPVQEAAARAALGEYVDGRGALARLL
GGFDHFTAGRKRLMFRTLLAELGAHSFPEVHSPEALFEAHGQQRWLITEMAALKVLYAFG
TGAPGLVTEEDWRALEPCSLPGPPPYGNHLARVLALLALRFHPRYAEAVRARARELRGRL
REDGGLPFITGMDVFATATGGLALAGAGAPAHTLRALAAALAEHRNPDGGWGFDRGVAQS
DVDDTSYCVEFLRAAGPGLFGAEVAAGERYLLARQGADGGFPTFERGTASEVAITAAAVN
ALAPEPAHRAAVEAAVRFATARQEAPGPFERSWSLNESNALFRTVLAHDSFLAVAPGHPA
RTEVARGRARAVERLLDTQNADGGWGHVPSDPSDPISTAYALIAVARTPTVPSARGATGR
AVHHLLERQRPDGGFVSRPDQAGPRPLAYHVPLLTDVCVLLGLNHARAYATR
>A0A8A8DAK6|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia seminalis|TrEMBL
MNDLTEMATLSAGAVPAGVDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGETPNLALEQKIGNYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARKAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPIAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDALGYAEDHPNRAL
ARKSVEKLLVVHEDEAYCQPCLSPVWDTSLAAHALLETGDARAEEAVLRGLEWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLKQSDTYRDSMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNHPAVARGVDYLI
AQQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNATRVTVGM
>A0A7Y2FRP6|squalene-hopene cyclase|EC 5.4.99.17|Hyphomicrobiales bacterium|TrEMBL
MPDEASDAAADAAGHLLELQQADGHIVYELEADSTIPSEYILLNHFLGDPEPEIEARLVA
HIRSLQNEGHGGWPLFYGGGFNISASVKAYYALKMVGDDPALPHMVRAREAILAHGGAET
SNVFTRYCLALFGQVPWDAVPVMPTELMLMPKWFPVNMWKFAYWSRVVIAPLLILAALKP
VAKNPNQTDCQELFVTPPSQITHWLINPTGSRWGEFFLILDRFLRPIEKHVFPRLRWRNQ
AISKAVEFITERLNGEDGLGAIFPAIANSVMAFDALGLSHDSKEFSTARTAIRNLLIETS
DKSEGRSYYCQPCVSPIWDTSLAGHALLEAGVEPDDERLIAACDWLAENQITEVKGDYSV
NAPDLAPGGWAFQYRNDHYPDVDDTAVVGALLHRVNPTRYAKEISRAAVWVEGMQSSNGG
WGAFDIDNNASVLNSIPFADHGALLDPPTVDVTARCLSFLAQLGYPQSHQVMRHGIEFIE
QEQEPDGSWYGRWGTNYVYGTWSALTALNACGVDMSEPFVRRAVDWLKVHQREDGGWGED
GATYWQERRYECKASTPSQTAWAVLALMAAGEVEDPAVSSGIRHLVDAPREDGKWQEPWY
TAVGFPRVFYLRYHGYSAYFPTWALGRYGRLMKSNSREVQWGL
>A0A7W5IMV1|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia sp. WP4_3_2|TrEMBL
MKKSDLPFAALLDAAIVRGRNALARRQQPEGSWCFELESDATITAEYILMMHFMAKIDTA
RQEKMARYLRAIQRLETHGAWDLYVDGAPDVSASVKAYFALKAAGDKENAPHMVRAREAI
LKLGGAAKSNVFTRILLATFGQVPWRATPFMPVEFVLFPKWVPISMYKVAYWARTTMVPL
LVLCSLKARAKNPHNVSIAELFVTPPEQEREYFARGKGVRRAFLVMDRLLRHVDPLIPGA
LRKRAIKHAEAWCAERMNGEDGMGGIFPPIVYSYQMMEVLGYPEDHPLRRDCENALEKLL
VERPDGSVYCQPCLSPVWDTAWSTMALEQSLTVPDTPAEEATEANIPRAELEQQIALAYD
WLAARQVDDLKGDWIENVKPDVPPGGWAFQYENPYYPDIDDSAVVVAMLHRRGRLQKQVT
GADPYAARVTLALDWMRGLQSRNGGFAAFDADCDRLYLNAIPFADHGALLDPPTEDVSGR
VLLCFGVTGREEDKASLARCIDYIKATQCPDGSWWGRWGTNYIYGTWSVLAGLALAGEDP
KQPYIARALAWLRSRQHADGGWGETNDSYIDPALAGTNGGESVSNFTAWALLAQMAFGDF
ESESVQRGIAYLLSVQDGEGFWWHRSHNAPGFPRIYYLKYHGYTAYFPLWALSRYRRLVS
AAQAKTHADTRESAKEKALAV
>A0A7C3DXR5|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MLVTKLETQATGAQVQTPHSAARALVPVVERAMQRAQHHLLGQQHPDGYWIGELMVDTTI
MSDMIAFRHWDGNVDPAWERKAANYILSQQLPGGGWNIYHGGPAEVNATIKAYLALKLAG
VPVTDPRMLRARAVALSLGGVPRMNTFSKLYLALLGMYPWKYVPTIPCEVLLIGKWFRVN
FWDMSNWSRAMLVPLAIINHFRPTRPVGCDITELFPEGYHERDLRLPRDPWPYFTWRNFF
LALDKLHKFAELWARAGIHPFRRRALRKAEQWMIERMDGSDGLAAIFPAILNSLIALKVL
GYPPDHPLMLRVESELRKLEHQNAEHVWMEPCLSPVWDTAIAAIALRESGVPADHPALKK
ATAWLLGKEIRFRGDWQHKNPADVEPSGWVFEFENKWNPDVDDTAMVLLALRLTPTDDPA
ARDAAYRRGLNWMLTFQCRDGGWAAFDKDCTNNILEKVPFADHNAMLDPECADITARILE
VLGHEKYPLDHPQVARAIEYLRKHQEPDGSWYGRWGVNYIYGTWQVLRGLHALGMDMHQP
WLRKAGEWLESVQHDDGGWGERCDTYEDPVFKGRGPSTASQTAWAVMGLCTFGDPNNAAL
LRGVEYLTRTQNPDGSWSEEETTGTGFPKVYYLKYDMYRNTWPLLALATFRKLVAGASGP
INGAAYGLPTSPVFAPQPARSP
>A0A5J6EZ73|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces galilaeus|TrEMBL
MTATTDGSTGALPPRAAAASETRIDIPAAAGVQEAAVRAVQRGADFLLARQDVEGWWKGD
LETNVSMDAEDLLLRQFLGIQDESTTRAAALFIRGEQRADGTWATFHGGPGDLSATVEAY
VALRLAGDEPGAPHMAKASAWVREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELLYF
PKWFPLSIYNFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPADPNPPRPPAPLASW
DGLFQRLDKVVRGYRRVAVRRLRGAALNSAARWIIERQENDGCWGGIQPPAVYSVIALYL
LGYDLEHPVMREGLKSLDRYAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHPQL
VKAADWMLGEQIVRPGDWSVRRPHLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHDP
DRVESAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAFEGLSHDPRTRRGISWLLAEQEPDGSWFGRWGVNYIYGTGSVVPALTAAGLPARHP
AIRRAVGWLERVQNEDGGWGEDLRSYQDPARWSGRGASTASQTAWALMALLSAGEKDSRA
VERGIAWLAETQREDGSWDEPQFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPLAAK
VPVPVEAEGS
>A0A6B3CRQ7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID6648|TrEMBL
MTATTDGSTGAANITGAPADDPTDTRTAANDVTDIARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPGDLSATIEAY
VALRLAGDRPDEPHMARASGWIRDQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPDHPNPPRKLAPPTSW
DGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMKAGLASLDRFAVRREDGARMIEACQSPVWDTCLATIALADAGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARLESAIARGVRWNLGMQSRNGAWGAFDADNTSAFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLASHPRTREGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALITAGLPAGHP
AIRRAVDWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDTASV
TRGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFADRP
DAAEGA
>A0A7Y6H2P3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. KAI 90|TrEMBL
MTATTDGSTGATLRPLAAAASENEITTPDTAAGVPEAAARATRRATDFLLSRQDAQGWWK
GDLETNVTMDAEDLLLRQFLGILDEETTRAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDAPDAPHMARASEWIRSRGGIAASRVFTRIWLALFGWWKWDDLPELPPEII
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAVPNPPRPLAPAA
SWDGAFQRIDKALHAYRRIAPRRLRRAAMNTAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHP
QLVKAADWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHH
DPERVEQAIGRGVRWNLGMQSKNGAWGAFDVDNTSSFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAVEGLTHDPRTRRGIQWLLAEQEADGSWFGRWGVNYVYGTGSVVPALIAAGVPAS
HPAVRRAVAWLESVQNDDGGWGEDLRSYRYVREWSGRGASTASQTAWALMALLAAGERES
KAVERGIAWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFA
QKSGAARPATETSTAEVKGS
>A3PA30|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia pseudomallei (strain 1106a)|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A838SFX8|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirales bacterium|TrEMBL
MLTSTRYLILETAIDLLGRDGASALTLEHVAREAGLSKGGLLYHFEGKEQLLVGLIELLI
QDLDRKQVGDFLTSSIYEEQPWTALDTDAVENPTNHRSLQGHEIASILMAALAINPHLLE
PIRERYQNWQSIFLANTDDPTRSLVGRLAAEGLWFSEALGLAPPTREQRAALVLEIQSHT
QPGESMREPSASITPTQPKNAFAELASFKSHVEELERQAYQPTQTSARALLAKQNPQGFW
QGDLTADTTLESDYVLLLLWLYPPEAGAWKPEIQIKIDKAMRTILDRQLSDGGWDIYSEG
PAEVNATTRAYVALRVGGYDPDQPLMQRARECILALGGLQATNSYTKNNLSMFGLFPRKY
TPSVPPELVLIPGNVLYEISSWSRAIVVPLSILQASGVQRKVPGNWTVDELLVPNRKLTF
PKKDPFSLMFHQVDKILKLWEKRGFKDIRAKAIREAEKWMLDHMRFTDGLGAIFPGMMYA
LMAMDALGYERDHPDFIDTLGQLEGLILEKEGALQFQPSLSPVWDTAISMFALGELGIGE
PEAMQRAADWLLSKEIRRKGDWSVKRPDLQPGGWPFQFANELYPDIDDTAMVLLALEHAK
ASDPDRQTRAESRAINWLFGMQSSDGGWAAFDVDNTWALLNKVPFADHNAMLDPSCPDIT
GRVLEALCRRDYTHQHPAIARAVQYLLVHQQANGSWDGRWGVNYTYGTFLALRGLRASGS
PTASSAVQRAAAWVRSVQNQDGGWGESCASYEKQEF
>A0A7C7FXX2|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirales bacterium|TrEMBL
MEQSIHYLLNQQDPRGFWVAELEADSTLTSEYIMLRRMLKKVDPEKERKKVSYLKAAQCA
DGGWPIYYGGPSNISASVKAYFALKLAGVSPDEPSMHNAREVILKMGGVVNTNVFTKIAL
ALFGQYDWQGIPSMPPEIILLPKQFPVNIHSVSYWSRVVLVPLLIIYASQPVNQVPKECG
IDELYVVPRNQIHVRRGPPFEADPRPVSWRNLFLLVDFALHLYSQRPLRPLRGLAIKKAT
DWMLERMQGNGGLGAIYPAMANSVLALHALGYGTDHPLVTKALSEIEELEVESEDMLHLQ
PCFSPIWDTCLLTNTLVESGLSRTHPGLLKAGHWMLSQQTKKVGDWKVSAPQAQPGGWCF
QFENEHYPDCDDTAVVLMALAKLDFPNKTEQRQAIIRGLQWLLPMQGRDGGWASYDKDNN
ATMFNEHPFADHKSLIDGSTADIVGRVLEMLGVLGFDRTFRPARKAIAYLKKDQEANGSW
YGRWGVNYIYGTWSVLAGLRSIGEDLSQPYIRKAVHWLKETQHDDGGWGESCQSYADQSL
AGVGESTASQTAWALIGLLCAGEVQSDNVTRGIESLIRSQKPDGSWEERFHTGTGFPRVF
YL
>A0A532EPQ4|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp|TrEMBL
MKLIRALLDRLSESFVVSVSEKLELATEPSNNPPLRLVLDKPLLSASADTVTRRSPGHSI
SQVDALDDAVRRSQAWFLSRQDASEGYWVAELEADTTLTSEYLMLRRFLNRVDPERERKA
VSYLRAMQLPDGGWPIFYGGPSEISASVKTYFALKLSGVSADEPCMLRARDRILAMGGVV
CANVFTKITLALFDQYDWKGVPSMPPEIMLLPKRFYFSIYAISYWSRAVLIPLLVVFAKQ
PVCRIPREQGIDELYLSPRAQIHYRDVPPFNKEQRWFTPHNFFVQLDRILKLYDQMPLSW
LREKALHEAATWILEHLKGSGGLGAIYPAMANSIVALRCLGYEVDDPLVQKALREIESLE
VYDTASIDDQQVETLHLQPCHSPIWDTALLMNALIETGMPQDHPSLQNAGAYLLSRQTTT
VGDWKFSSPNAKPGGWYFQFENEFYPDVDDSAVVLMALSKVRIGQTPESQASIRRGMDWV
LAMQGSDGGWGAYDKDNNRIVFNYIPFADHHALLDPSTSDLTGRCLEMLAALGYDQTHPA
VGPALRFLRREQEADGSWYGRWGVNYIYGTWSVLAGLRAIGVDLSDPAISRAVAWLESKQ
NPDGGWGESCHSYGDPASSGKGDSTPSQTAWAIMGLMSAGMADAFSVARGIQYLLRHQTK
EGSWEEVRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRTRGTMRADEVRQQVFASGC
HRADH
>A0A410VH24|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium guangdongense|TrEMBL
MDAVNAISREALESSIASATQGVLGFQQPDGHWVFELEADCTIPAEYILLRHYLAEPVDT
ALEAKIGNYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDSVDAPHMVRAREAIH
ARGGAINSNVFTRFLLATFGVMTWRAVPVLPIEIVLLPFWSPFHLNKISYWARTTMVPLM
VIAALKPLAKNPKRVGIDELFLQDPRSIGMTAKAPHQSMAWFVLFRALDGILRVVEPMFP
KSLRQRAIDAALAFIEERLNGEDGMGAIYPPMANIVMMYDALGKDANYPPRATTRRGIDK
LLVINGEEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLDWLIPKQELEVKGDWA
VKRPDVRPGGWAFQYNNAYYPDLDDTAVVVMSMDRMRREHGVAGYDAAIDRGREWIEGMQ
SDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGQTEATSKQVAA
GVAFLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDQKDPMIRKAAAWLTSIQNED
GGWGEDAVSYRLDHKGWEAAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIATQGEKG
LWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A8I0P911|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces stelliscabiei|TrEMBL
MTATTDGSTGALPPRAPSASDTDHGTPVAAGVQEAAVHAVRRATDLLLARQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDDRTTRAAALHIRGEQRPDGTWATFYGGPSDLSATVEAY
VALRLAGDDPAEPHMARASAWIRERGGIAAARVFTRIWLALFGWWKWDDLPEMPPEILYF
PQWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHADPGRPNPPRPLDPLGSW
EGAFQRLDRALHGYHRVAPRRLRRAAMNRAARWIVERQENDGCWGGIQPPAVYSIIALHL
LGYDLRHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQL
VKAADWMLGEEIVRPGDWSVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHDP
ERVEKAVRRGVRWTLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAAEGLSHDPRTRRGIEWLLAEQEPSGAWFGRWGVNYVYGTGSVVPALVTAGLPAAHP
AIRRAVAWLETVQNDDGGWGEDLRSYPDPAEWGGKGASTASQTAWALLALLAAGERDTKA
TERGVEWLARTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPALLK
PGGR
>A0A7K2MA33|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5998|TrEMBL
MTATTDGSTGATLPTRAAAASEPVLTTPVAAGVHQAAEHAVRRATDFLLSRQDAEGWWKG
DLETNVTMDAEDLLLRQFLGIQDEATTHAAALFIRGEQREDGTWATFYGGPGELSTTIEA
YVALRLAGDAPDAPHMAKAAAWVRARGGIAASRVFTRIWLALFGWWKWEDLPELPPELIY
FPTWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAQPNPVKPMAPAAS
WDGAFQRLDKALHAFRKVAPKRLRRSAMNTAARWIIERQENDGCWGGIQPPAVYSIIALH
LLGYDLQHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQ
LVKAADWMLGEEIVRPGDWSVRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHD
PERVDRAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGLAHDPRTRRGIQWLLEEQEPDGSWFGRWGVNYIYGTGSVVPALTAAGLPGSH
PAIRRAVAWLKRVQNDDGGWGEDLRSYRDSKKWSGKGASTASQTGWALMALLAAGERDSE
AVERGVRWLADTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFAA
QAPAGRPLAEAKGS
>A0A5C8ALB3|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus sp|TrEMBL
MTPLARPVFPFESPELTLLAEPKSVEESIAKAQGNLLRQQRADGHWEAELLVDSTLCSDY
VLYMHWSDRVDEDLQRKCIAHIRRRQLSDGGWNIFINGPSEINASVKAYFALKLAGHSPN
APWMREARANILRLGGIPATNTYAKLYLALLGQFPWKYVPTIPPEIFLFPQWFFFNLSEM
SSWTRPILAPLTILNHFKPTRTLPAEFQLHELYPAGLENTDLSLKKEPRFWAWRNFFLRC
DQLLKIYNSIPFHPLRQHALKVAEKWMTERMGEGSEGLAAIFPSMLNAMMALKVLGYKDD
HPLVQKADRDFAGLFVDDPEDFRIQPCLSPVWDTAITTIALAESGLPGTDEAMQHAAQWL
EDREVRFVGDWAQRVSGIEPSGWAFEHDNKYYPDTDDTMMVLMALRHVPAKDKAKRDAQF
QRALKWLLAFQCEDGGWAAFDKDVTARWLEHVPFADHNAILDPTCSDLTARVLELLGYIG
YDRESMVVKRAVAMLRRTQEADGSWYGRWGVNYLYGTWQVLRGLAAIGENMDQEWIRRGR
DWLESCQNEDGGWGETCESYNFPALKGRGPSTASQTAWALMGLCACGDASRESIERGVAY
LTRTQEPDGSWTEDYTTGTGFPCVFYLKYEMYRQHFPLLALATYQQMVQR
>A0A7V2HBM8|squalene-hopene cyclase|EC 5.4.99.17|Bryobacteraceae bacterium|TrEMBL
MSSGVQLADALSLETARAIERASQSLYSRQHRDGFWWGDLTADSTLESDYLLLQLWLHPP
VNGQWNPPTKDRIARAVQSILGRQLPDGGFPIYPHGPSEISASVKAYFALKLGGLPADDP
RLRRLRQRILDLGGVQAANSYVKINLALFGLYPREFAPRVPPELMLLGDLIYEMSSWTRA
IVIPLSIVQASGPRPAPAGFTLEELFHPDKPLRFPNPDGLLSWRQFFLTANAAFRLWERY
GHQGIRQKAIRMAEKWIVEHTEHSDGLAAIYPAMQYAIMAFDALGYGASHAVRLEAEQQF
DALLVDDGDRFFFQPCFSPVWDTAIAAYALGEAGAIRRTPMERCADWLLSKEVRRPGDWR
KKRPDAEPSGWYFEFANEFYPDIDDTAMVLLSLRHAQSADRGRQQAAIARAVSWLIAMQS
RDGGWAAFDADNDWQFLNSVPFADHNAMLDPSCPDITGRVIEALATHGVSRKHPSIRRGR
EFLLRNQEEDGSWYGRWGVDYIYGTFLALRGLQAAGEDNREAHILRAGEWLRSVQNADGG
WGESCASYDRNAFVAGPSTASQTAWALLGLLASGDADSQSVHKGVEYLIETQTPDGRWDE
DYATGTGFPRVFYLTYHLYRDSFPLLALASFLSNRNRGRGDLT
>A0A6I6UX43|squalene-hopene cyclase|EC 5.4.99.17|Rossellomorea vietnamensis|TrEMBL
MKKKIESTIRNMISDLQRMQREDGHWSFCFENVVMTDAYMIILLRTLAGDEDELVGQLVD
RLWNRQSREGTWKLFEDEKEGNLSSTIEAYFALRFSGMVNEEDKRLLKAKRFIEKKGGFH
KAHTMTKFMLAVHGQYEWKHLLPIPIEFLLLPKTFPLNFWDLSSYARGHLAPMILLKDQK
FKIQTSSIPHIQDLSRAVKEERYSEREWRLFSKISEGIQALAGLPSQLHQQARQFALEYM
LQRMERDGTYLSYFSATFYMIYAMLALGYKKNDPIIVKALQGLKDMACETKKGIHIQNSP
SAVWDTALISHALQEAGVDANEDVIQKSVDYLLKKQHFKYGDWAMETGVKPGGWGFSESN
SIHPDVDDTTAALRALTYSAAGNPLIRQSWDRGIDWVFGMQNRDGGWPAFEMNKTKSILT
SFPMDGAEAAAIDPSTPDLTGRALEFLGSRAGLTAEHPDVKKGVEWLKLMQKEEGSWYGR
WGVCYIYGTWAAITGMKAVGVSSSDIHLQKAKTWLESIQRKDGGWGESCYSDQEKTFVSL
PFSTPSQTAWALESLICIEDKPTPAIDLGIMALLELTNGADNETSQAYPTGIGLPGNFYI
HYHSYQWIWPLITLSRYKEKFG
>N0D069|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces fulvissimus DSM 40593|TrEMBL
MTATTDGSTGAANLSAPPAGHPADTTTAADDVLEAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGILDPETTRAAALFIRGEQLGDGTWNTFYGGPSDLSATIEAY
VALRLAGDRPDEPHMARAATWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPAHPNPPRKLAPAASW
DGLFQRLDKGLHLYHRLAPRPLRRIAMNVAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMVEACQSPVWDTCLATIALVDGGLRPDHPAL
VRAADWMLAEEITRPGDWSVRRPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVHHPDP
ARLEAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLGSHPRTRRGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALVAAGLPAAHP
SIRRAVTWLESVQNDDGGWGEDLRSYTEEKWIGHGESTASQTAWALLALLAAGRRDSRAV
ARGVTWLTGAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYAYGDPFADRT
GAAKGA
>F2NEV8|squalene-hopene cyclase|EC 5.4.99.17|Desulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2)|TrEMBL
MLRALKPHKTVLSWADAYISDKVEQAAAKAQKALLELQHPDGYWWAELEANVTITSEYIM
LRSFLGLADADRFSRMANYILSQQLDNGGWSIYHGDGGDLSTTVEAYLALKLAGLQTTMP
EMQQARQFILSRGGPLQSRVFTRIFLALFGQVSWRGIPTMPVEFVLLPLWTGLSIYELSS
WSRATVVPLSVVMAYQPVCPLPPDRGVRELFHPWEDPLRDHRVRLKKNGLSLDNLFVFSD
KLLKVYQGHPYPPLRQWALRRAEEWILTHQEETGDWGGIQPAMLNSILALHCLGYSNKHR
AIKLGLEAMEFFTLAAGNRLWLQSCISPIWDTALSVRALTASGLQGTHPAVSKACQWILQ
QQIFRRGDWSVKNPYLAAGGWAFEFHNNWYPDIDDSAVVLMSLAEGLQEPQQHRTALDRG
VHWCLGMQSQNGGFAAFDTDNTKAWLNHIPFADLKALIDPPTEDVTSRVLEMMGMFGYTA
DHVAASKAIAFLKSAQQPDGCWYGRWGVNYIYGTWSVLCGLKGIGEDMSSPYIRRAVAWL
QDHQNEDGGWGETCASYKYPELRGQGPSTASQTAWALLGLIAAGEAGSPAVAKGIRYLVQ
TQTPSGRWEEPYFTGTGFPQHFMIRYHLYRDYFPLMALGNYLKSRGHYPDV
>A0A7K3AR02|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8378|TrEMBL
MTATTDGSTGAANITGAPTDDPTDTRTAANDVTDIARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPGDLSATIEAY
VALRLAGDRPDEPHMARASGWIRDQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPDHPNPPRKLAPPTSW
DGLFQRLDKGLHLYHKVAPRPLRRVAMNVAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMIEACQSPVWDTCLATIALADAGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARLEAAIARGVRWNLGMQSRNGAWGAFDADNTSAFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLASHPRTREGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALITAGLPAGHP
AIRRAVDWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDTASV
TRGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFADRP
EAAEGV
>A0A534X6G5|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MSSEGRLVLVGGTEAADGGLGARAGQAIARATQYLVATQHPHGYWHAPLEANVTMEAEYV
FFNRMLGRDRPDLDRRMAERMLALQQADGSWPQYREGPGNLSTTIEAYFALELAGLKADE
PALARARDFILGHGGLARAGVFTRFWLAYFGQFPWAGLPALPVELVLLPPWFPVNIYAMS
SWARGTVVPLALLAAHRPSVPTPPGAQLGELWTRTPTRADLAFPRSRELITTRNFFLALD
RAIRLLGQSPWKPLRRRAIARAIEWLVRHQDRNGQWGGIQPAMLNSVLALHTVGFAPEHP
AMVSGIQGVDDFLVECEGTLVYQPCVSPTWDTALAMKALLESGTDPAHPMLGRAAEWLIA
NQIFRPGDWSVLNPALEPGGWAFEFANDSYPDVDDSAVILMVLGQLPIAATPAGRRAIAY
GLNWTLGMQSRSGGWAAFDTDNTAGFLNRIPFADMEAMIDPPTEDLTGRLLSLLGAYGYG
ADFGRARRALEFVRRTQRPDGSWWGRWGVNFIYGTWSVLDGLAAIGEDLRAPWVRRAVEW
LKARQNPDGGWGETVASYDDESLAGKGESTASQTAWALLGLMAADGVASPAVQRGTDWLV
RTQGANGTWTERLFTGTGFPRHFYLRYHLYRHYFPLMALGRYVRLVGEGERR
>T2AYJ0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWAANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDRYSEATARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGRWG
>T2B068|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYCEAIARGAEWITGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGSWG
>T2AXK6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYLDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWYGRWG
>T2B012|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAALALQEANPKATRHSREKAYNWLKTKQLDKQPGDWQIQQPHLNGGGWAFQF
ENPHYPDVDDTAVVAFAMANACDLNNLEESIHRATHWTAGMQSKNGGFGAFDCDNTDYYL
NHIPFADHGALLDPPTADVSARCAMLLGHQLNSHPEYQKTLDKTITFLRKEQESDGSWFG
RWG
>T2AZ40|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLATHAMLEANLSSGPSILGNGSTSKACKWLEKLQIKDCAGDWAVWRPNPRPGG
WAFQYHNDYYPDIDDTAVVAMALHRTENKIYEPALLRAAEWIVGMQSKNGGWAAFDADNE
YHLLENMPFADHGALLDPPSVDVSARCISFLTQLGYDQANGTIKRGIEYLKKNQEEDGSW
FGRWG
>T2AZF3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGSW
G
>T2AYX6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAITLLSLADKKIYSKNIKDGINYIKSEQEEDGSW
>T2B0E5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLATHAMLEANLSSGPITIKNDCTSKACKWLENLQIKDCAGDWAVRRPNLRPGG
WAFQYHNDYYPDIDDTAVVAMALHRTGNKVYEPALLRAAEWIIGMQSKNGGWAAFDADNR
YHLLENMPFADHGALLDPPSADVSARCISFLTQMGYDQTNGTIKHGIEYLKKNQEEDGSW
YGSWG
>T2B0D5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PMWDTGLAAHAVLETLGGNTLLLNKSCDWLSKLQIKEHTGDWGWRRKGLRPGGWAFQYNN
KFYPDVDDTAVVGMALHRQNPEKYADTISRAEEWIIGMQSSNGGWAAFDADNEYYLLENL
PFADHRALLDPPTADVTARCISFLTQIGTSNNHPISRGLEFLKRNQEEDGSWYGRW
>T2AZL8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTAICSNALLDSGLPTDHPALVRAGKWIVSKQVTKRGDWQVKNPKAEPGGWAFEFY
NELYPDTDDTAEILLFLNRVEIPDNRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGKWGFNKQHPQVKRAIKFVKERQEIDGCWFGR
WG
>T2B0H3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQRVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVVWAMHRTNNKSYSEPIQRAANWVAGIQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAITLLSLADKKIYEKNIKDGINYIKSEQEEDGSWFGRW
G
>T2AXL2|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTAICSNALLDSGLPTDHPALVRAGKWIVSKQVTKRGDWQVKNPKAEPGGWAFEFY
NELYPDTDDTAEILLFLNRVGIPDNRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGKWDSINSTRKSKGPSSLSRNGRKSMDVGMDD
GA
>A0A1P8TC46|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces alfalfae|TrEMBL
MTATTDGSTGAVTPRAASASHSIDTPAATAPTAGTREAAALAIQRSTDFLLSRQDAEGWW
KGDLETNVTMDAEDLLLRQFLGIGDERTTRAAALFIRGEQREDGTWATFFGGPGELSTTI
EAYVALRLAGDLPDAPHMARAAEWIRDRGGIAESRVFTRIWLALFGWWSWDDLPELPPEL
IYFPPWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHVDARVPRPPKPLAPA
TSWDGLFERLDKALHVYHKVAPRRLRGAAMNSAARWIIERQENDGCWGGIQPPAVYSIIA
LHLLGYDLEHPVLKAGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADH
PQLVRAADWMLGEEIVRPGDWAVRKPRLAPGGWAFEFHNDNYPDIDDTAEVALALRRVAH
PDQARVDNAIARGMRWTLGMQSKNGAWAAFDADNTSPFPNRLPFCDFGEVIDPPSADVTG
HVVEMLAVEGRSHDPRTRRGIEWLLAEQEDNGAWFGRWGVNYLYGTGSVVPALITAGLPA
SHAAIRRAVRWVESVQNDDGGWGEDLRSYRDRGWVGHGTSTASQTAWALLALLSAGERDA
PSVERGIAWLAATQRPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPFP
AGSAHAGKGS
>R9VY76|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAITGHALWDTRDAAAEAAVAKGLEWLKPLQVLDVKGDWAGEKPGVRPGGWAFQY
RNDHYPDLDDTAVVVMAMDRARSDQPSAEYKDAIGRGAEWVEGLQSRDGGWGAFDADNSY
YYLNNIPFADHGALLDPPTEDVSGRCVGMMAQLGATQDTSSALAQGVDYLIRTQRDDGSW
WGRWGVNYIYGTWSALAGLNAAGLKPGHTTMAKAADWLVAIQNPDGGWGE
>R9W2N0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAQVLSPVCDRGLSRTDPRLLKAADWLLSKEIRYKGDWSHNVKDVDASCWCFFFN
NDHQPDVDDTGEVLLALRAVDNPRERYQHEVAQRAIEWVFAMQCKSGGWASFDKDNTKKM
FESIPFADHNAMIDPPTVDITGRILEMLASYGYTRRDKRVEKAVQFILQEQESDGSWFGR
WGVNYLYGTFLVLRGLRAMDFDSYEPAVQQAAEWIRMVQNTDGGWGE
>A0A6G2QGN3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID7804|TrEMBL
RLDRTLHALRRAVPRRLRAAAMHTAARWIIERQENDGCWGGIQPPAVYSIIALHLLGYDL
NHPVMRAGLESLDRFAVWREDGARMVEACQSPVWDTCLATIALADAGLPADHPQLVKAAD
WMLGEQIVRPGDWSVRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHHDPERLDN
AIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVVEMLAV
EGLAHDPRTRRAVQWLLAEQEPDGSWFGRWGVNYLYGTGSVVPALTAAGLPGSHPAIRRA
VAWLESVQNDDGGWGEDLRSYRHAREWAGRGTSTASQTAWALMALLAAGERESRAVERGV
EWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFAARPAAAS
ARA
>F7QL34|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobiaceae bacterium SG-6C|TrEMBL
MTLLDDHRAAAAPSAPALENSIEAASSAILDVRKADGHWVFELEADATIPAEYVLLRHYL
AEPVDSVLEAKIGNYLRRIQNDNGGWSLFYGHEFDMSASVKAYFALKMIGDKPDAPHMKK
AREEILRRGGAIKSNVFTRIMLALFGVVTWRAAPMMPVEIMLLPRWFPFHLTKISYWART
VIVPLLVLMNKKPRARNPLGIGIDELFLEDPKSIGMTAKAPHQSQLWFTGFDLLDKILRV
VDPLFPKAPRQRAIDKAVAFVTERLNGVDGLGAIFPAMANTVMMYDLLGYPKDHPHYVLA
RQSIENLLVIKDDEAYCQPCVSPIWDTALTAHTMIEVGGEKAEASAKAALDWLKPKQVLD
VEGDWIEKRPGVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRARGTLNAGEKYDEAIARGR
EWIDGLQSKDGGWAAFDADNLEYYLNNIPFSDHGALLDPPTEDVTARCVSMLAQLGETVE
TSPALARGVEYLRRTQLADGSWFGRWGVNYIYGTWSVLCALNAAGVDHKDPVIAKGADWL
ISIQNPDGGWGEDGNSYKLEYRGYERSESTASQTAWATLALMAAGKVDHPSVQRGIAYLI
QFQGKDGLWTEPQYTGGGFPRVFYLRYHGYSKFFPLWALARYRNLRNTNSRFVGIGM
>A0A7V1V628|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
MKLLKTLLTRLSENLFASVPGRRKRSAAQRSSPPLRLVSHNPHPTMAAESPSRRMSGPAP
GHAEWLDEAIRRSQAWFLGRQDPQEGYWVAELEADTTLTAEYVMLRRFLGAVDPERERRM
VRYLRHMQLPEGGWPIYYGGPSEISASVKAYFALKLAGVSADEPFMVKAREAILAKGGVV
AANVFTKIALALFDQYDWRGIPSMPSEIILLPKRFYFSLYAMSYWSRAVIVPLLIIFAHR
PVCRVPAEQGIAELWVQPREQVRYRNVPPLRKDPQWLTWRNVFITIDSVLKLFERAPIKA
LRARALARAAQWMLDHMKGTGGLGAIYPAMANSVIALHCLGYSNDHPLVLKALKEIEELE
VYDTVREHEGIGQPTLRLQPCFSPVWDTALLINSLIEAGLPPDHPALMRGGAWLVSKQAT
AVGDWIVSSPEAKPGGWYFQFENELYPDVDDSAVVLMALSKVRMADRDAQRAAIARGFRW
VLAMQGSDGGWGAYDKDNNRMVFNLIPFADHRALLDPSTSDVTGRCLEMLGTFGYDMTHP
AAVRALEFLQRAQEADGSWYGRWGVNYIYGTWSVLAGLRAIGADMSAPYVRRAVAWLEAR
QNPDGGWGESCLSYADQKEAGRGESTPSQTAWALIGLLSAGITDSLSVVRGVNYLLKHQR
DDGSWEEVRHTGTGFPRVFYLRYHWYCHYFPLWALAMYRNMRARGQSKADELRQAARVAG
WLRLDA
>A0A3M1QML8|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
MATASPPRPPAEAPAAAEVAAAVARARDGLLALQHPEGYWSFELEADCTIPAETILWMHF
TDEVDAGLQARLAAYLRRHQEGDAWPLFFGGEPDLSCSVKAYYALKLAGDDPEAPHMRRA
RAAIRAAGGAERANVFTRIALAQFGQVPWRAVPFIPVEAVLLPRWFFFHLSRVSYWSRTV
MVPLFILCSHKVAAVNPTGTGIRELFVTAPERARYFSPASGLGRLFLAVDRAGRLLEPAI
PRRLRDRATRAAEAWFTARLGKGGLGAIFPAMVNAHEALVHLGYAPDHPLRQEARQALLD
LVVERSPEEAYCQPCNSPIWDTGLACLALEEAAGGEATPEVRRALAWLAGEQLLEAPGDW
RESHPDLPGGGWAFQFHNPHYPDLDDTAVVAWALHQAGGHEERVARAAAWIAGMQSRGGG
FGAFDSDNTDAYLNEIPFADHGALLDPPTADVSARCLTLLSRLGDRHREARERCLAYLAR
EQEADGAWFGRWGTNYIYGTWSVLTALEAAGVGRDDPRVRRAVAWLVRRQNEDGGWGESN
ASYFPGREREPAPSTCFQTAWALLGLLAAGERESAAVARGVRFLLERQGEDGLWADPGFT
APGFPRVFYLKYHGYSRYFPLWALARYARGG
>A0A533YN02|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
MKLIKIKNLITRLSDSLFASVPGRLKLGARTGLLPPLRLVSHNPRLTVPPEATARRVVGG
SIGQSESLDEVIRRSQAWLLGRQHPVEGFWVAELEADSTLTSEYLMLRRFLDLVDPDREC
KAVRYLQTTQLPDGGWPIYSGGPSEISASVKAYFALKLSGVPADESFMIRARDAILAKGG
VVAANVFTKIALALFDQYDWRGIPSMPPEIMLLPKRFVFSLYAVSYWSRTVLIPLLIVFA
HRPICRLPAEQGIEELYLEPRARVRYREVPPFKKDAAWWTWRNLFITLDSILKLYDRLPL
QTLRKAAVTKAADWMLDHLKGSGGLGGIYPAMANSIVALRCLGYSVDHPLVVKALREIEE
LEVYEVVNEGRGQVETLHLQPCFSPVWDTSLLINALIEVGFPQDHPALLKAARWLISCQT
TKDGDWKVSAPQAEPGGWYFQFENEMYPDIDDTAVVLMALAKLRLASRDAQHHSIARGYQ
WVMAMQGSDGGWGAYDKDNNRTVFNLIPFADHRALLDPSTADLAGRCLELLGTLGYDRTH
AAVGPALQFLRQEQEADGSWYGRWGVNYIYGTWSVLAGLRAIGEDMTMPYVRKAAAWLES
KQNPDGGWGESCVSYADPTMAGVGDSTASQTAWALIGLLSAGVTDSISVVRGVNYLLRHQ
RQDGSWFENRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRTRGQTRADELRLNAREA
GCFRFPS
>A0A533XZA4|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
MKRWLGLLTNWSEKILSAAPERVQQQARQKAGRLLRLVGGNPNAFLSAQAAQRRHDSGQV
PGQSVAHKGDAIDEAIKRSQRWLLQRQAEAGYWVHELEADSTLTSEYLMLRRFLDLVDAE
KERKAVRYLIAAQLPEGGWPIYNGGPPEISASVKAYFALKLCGVSAAEPFMEKARTVILS
QGGVVGTNVFTKIALALFDQYDWRGIPSMPAEIVLLPPWFVFNSNRLSYWSRTVLTPLLI
IFHFKPVCRIPTEQGIDELYLTPRTLVDFRHEPPFRRDRRSLTWRNFFIRLDGALRQYER
VVPQVLRKNAIARAAQWMITRMEGDGGLGAIYPAMANSVVALRCLGYEADHPLMRKAVSG
IEALEVYEGDALHLQPCFSPVWDTPLTINSLIESGLPQEHPALVKAARWILSRQCRKVGD
WIVSSPKAEPGGWAFQFENAFYPDNDDTAVVVMALSKVKMPEWDAQREGIRRGMRWTLAM
QGSDGGWGAYDKDNNKMFLNQIPFADHRALLDPSTADLTGRELEMLGMLGFDRKHPAAVR
ALRFLRKNQEADGSWYGRWGVNYIYGTWSVLAGLKAIGEDMQAKYVRRAVAWLVSKQNPD
GGWGESCLSYAEADAHGAGESTPSQTAWALIALLCAGEVDSLSVVRGVNYLLRQQDAQGS
WPESKHTGTGFPRVFYLRYHGYCQYFPLWALSMHRSVKARGRARADEIQEQNRQHGRFRF
EA
>A0A838V8M8|squalene-hopene cyclase|EC 5.4.99.17|Sphingomonadaceae bacterium|TrEMBL
MTIDILGDAEACASRAAEALAALQRDDGHWVFELEADATIPAEYVLLKHYLGEPRNAVLE
AKIGRYLRRIQANHGGWPLFHGGAFDVSASAKAYFALKMIGNDIGAPHMERARAAILAAG
GAEAVNVFTRIQLALFAAGPWRTVPTLPVELILLPRWFPIHLSKMSYWARTVIVPLLVLA
ALRPVARNPSGVRVDELFTGKPAPLSSKAANAKRLWQAFFGGLDRVLKAVEPLWPKRRRR
HAIEACVAFVTERLNGEDGLGAIYPAMANSVMMFDCLGYAEDHPHRAIARRSVEKLLVVG
EDEAYCQPCVSPVWDTALAAHAMMEAGGEGNERRADAALAWLKPLQVLDVKGDWAGERPE
VRPGGWPFQYRNADYPDLDDTAVVVMAMERAKGRTGETCDEAIARGVEWTAGLQSRDGGW
GAFDADNSHHYLNNIPFADHGALLDPPTTDVTARCVSMLAQLGETDTSRMKAALAFLEKE
QEADGSWFGRWGVNYIYGTWSALCALNAAGVASDAQMVRKAIDWLISIQNADSGWGEDCA
SYALDYRGYAAAPSTASQTAWALLGLMAAGEIGHPAVERGVRHLIATQDERGLWGQDAYT
GGGFPRVFYLRYHGYPAYFPLWAVARYRNLKRSNQSRVAFGM
>A0A845XS50|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO3B2|TrEMBL
MQTQDRIVESGVTGAIANSQSYLLAQQYPDGYWWAELESNVTITAEIILLHKIWGTDKQR
PLHKAEAYLRSQQRKHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDSALVRARDFILR
RGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPEWFPFTIYEMSSWARGSTVPLLI
VFDQKPVFEIEPRINLDELYTEGADQVKFELPRNSDWTDLFVLLDDGFKLAEDLNLVPFR
KEGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPIVQRGLEAIDRFAIE
TPDSYRVQACVSPVWDTAWVLRAMVESGLEPDHPALVRGGEWLLQQQILDYGDWVVKNPQ
GKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLKQAAMARGLAWIASMQCNQGGW
AAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEMLGSCNLSIESQKLENAIAFLIQ
EQEADGSWFGRWGVNYIYGTSSALSALSKIAPHTHQRSIERGAAWLVKCQNLNGGWGETC
LSYDDPTLKGLGISTASQTAWALIGLMAAGEATGNWAMDAIEMGVNYLVSTQQPDGSWDE
TEFTGTGFPSHFYLKYHFYQQYFPLLALGRYQISISS
>A0A7Y3W4F7|squalene-hopene cyclase|EC 5.4.99.17|Parvularcula mediterranea|TrEMBL
MASMTSGLPRENERQELIREQAEKLFGIQKDDGHLVFELEADATIPAEYVLLLRFLGESN
AKEEEGVRRYLLADQKENGAWPLFRGGAGDLSATVKAYWALKICGQDPESEPMLRARTWI
LGKGGAARANVFTRYSLALFGHIPWRGTPSLPVEVMRLPKWFPFHISKVAYWSRTVMIPL
LVLVAKKARAKDCSVKIDELFVTPPHEERRWQTNPNGTAVGHVFLALDKILHAVEPTIPE
SLRGGAIREAEEFVVGHLNGEDGLGAIYPAMANAVMMMATLGYADDDPRMKIARKSIDLL
KVWRGDQLYVQPCVSPVWDTALSSHALLEAGASNDPRLGAMLDWLASKQILDHRGDWTVR
RPGVRPGGWAFQYENPDYPDVDDTAVVAMAMHRQGSERYAENIERACEWLEGMQSASGGW
GAFEPENEHFYLNAIPFADHGALLDPPTVDVTARCIGCLAQVDPERYKSAIEKGLDYLKS
EQLPDGSWFGRWGANYIYGTWSVLVCLEQAGVDLREPWVRRAAQWLKTQQRPDGGFGEGL
ESYEEPGRGDIVHSNPSQTAWAMMGLMAAGEVRSDEVAKASAFLQNAPREEDSPRWAEGL
YTGTGFPRVFYLKYHGYAAFFPLWAQARYERMSKANDPRQGWGM
>A0A371RZU4|squalene-hopene cyclase|EC 5.4.99.17|Bacillus sp. HNG|TrEMBL
MRHRVYKEINRIANQVVQDQSEDGAWRYPFEIGIATDCSMIILLRTLEINDEEFIKELVK
RIAGKQQKDGSWKLFHDEEKGNLTSTVEAYYALLYSGYRDQKDQEIQAARRFIEANGGAT
EVHMFLKIILAITGQCAWPHFPINIEVMLLPDSFPINLFDLSVYGRANIIPFLILANTNF
RKRTPRSPNLSDLFQKKDVRFFTEDQADEARSVIKLIKHGIKGLKSHVNLRELALYRAEK
YMLDRIEPDGTYLNYFSTTSLMIYALLARVYPTTHPVITRAVKGLKAMTCRIDEDLHCQY
TTASVWNTALINYALQESGVPYSSTSIQMANHYILSRQHLKYGDWVIHEPNLLPGGWGFA
DMNTIHPDIDDTTAALRAIRTLAKEQVDCRQAWDRGVNWLISMQNKDGGWAAFEKNVDKK
VLNLLPIEGGKDLLIDPSTVDLTGRTLEFFGNYTHLDLHHPMVKRGIRWLLRHQNSDGSW
VGRWGVYIYGTWAAVTGMVAVGVSPNHPAIQKALNWLRKIQNPDGGWGESCKSDIKNCYV
PLGESTRTHTAWALDTLISAATGVTPDIENGVAFLVDKKEKDWTATYPKGRGMAGSFYLN
YHCYEYVFPLISLAHYQKLVGGQLLTGLSHENFI
>A0A6G2Z5Q4|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID3915|TrEMBL
MTATTDGSTGAANLRAVPFGDPIEPTIDTDDVLAAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPATVQAAARFIRGEQLGDGTWNTFHEGPADLSATIEAY
VALRLAGDRPDDPHMIRAAGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMFF
PTWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFTLDELHTDPEQPNPPRPLAPVASW
DGVFQRLDKALHVYHKVAPRRLRRIAMNAAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVMRAGLASLDRFTVWREDGSRMVEACQSPVWDTCLATIALADAGVPSDHPAL
VRAADWMLGEEIVRPGDWSVRRPQLAPGGWAFEFHNDNYPDIDDTAEVALALRRVRHPDQ
PRVDAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGRADDPRTRRGIRWLLDEQEACGAWFGRWGVNYIYGTGSVVPALIAAGLPTGHD
AVRRAVAWLESVQNDDGGWGEDLRSYREEKWIGHGSSTASQTAWALLALLAAGEREGRAV
QRGVTWLAETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFAKGA
GTGPGAASGKGA
>A0A5P6P113|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium betae|TrEMBL
MDSVNATSREAKEPRILESKILESSIASATDGVIGFQQPDGHWVFELEADCTIPAEYILL
RHYLAEPVDTVLEAKIGNYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDSVDAP
HMVRAREAMHARGGAIHSNVFTRFMLAMFGVTTWRAVPVLPIEIVLLPFWSPFHLNKISY
WARTTMVPLMVLAALKPRAKNPKGVGIDELFLQDPRSIGMTAKAPHQSLAWFVLFRALDG
ILRVVEPMFPKSLRKRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKDENFPP
RAITRRGIDKLLVINDDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAARQGLDWLIPK
QELSVKGDWAVKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGVAGYDAAID
RGREWIEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGE
TEKTSKHVADGIAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVRHDDPMMRKAA
AWLASIQNEDGGWGEDAVSYRLDYKGWEAAPSTASQTAWALLALMAAGEVDHPAVARGVE
YLIATQNKKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A7C7VVR7|squalene-hopene cyclase|EC 5.4.99.17|Nitrospinaceae bacterium|TrEMBL
MTKSEDEGSAQEPSPISMDAKGEVLDKAIERSREFLLSCQDEKGYWVDELEANVTISAEL
IFFMHFTDRLDLVKQDQIVKYLLDLQREDGGWPLFYGGLCDINSTVEAYMALKMAGLPAD
REEMILARQAIFANGGIKTTRVFTKMFLAMFGQLSWDDCPAVPVEIILLPNWFPFNIYEI
SSWSRGTVVPLSVVRSLKPVHKFPEGKDIQELFADKDGDLGLKPDGLSFTSWSNTFIYLD
RFIRAIGKFPWKPFRKIALCKVEKWTLEHQEDEGDWGGIQPAMFNALLALHLLGYPKDHP
ACVKGMEAVDRFLLKKDGRLWMQACVSPLWDTAIAANALLDSGLPSDHPALIKAGEWIIR
KQVVKRGDWQVKKPGAEPGGWAFEFYNELYPDTDDTAEILIFLNRVDIPNNRWKLSECGR
AMDWLLSMQSKKGGWGAFDVDNDKELLNKIPFADHKALLDPPTSDVTSRILWMLAKWGFK
KQHPQVQRAIQFVKENQEIDGCWFGRWGVNYIYGTFLALNGLSAIGEDMQAAFSRKAVTW
LVDHQNEDGGWGETCQSYAEPSLRGRGKSTASQSAWALLGLIAAGVVENPAVERGVRYLI
ATQNESGKFSGSWWEDEFTGTGFPVHFFIKYHMYQHFFPLMALSHYRRAAKC
>A0A3N9FSE0|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cenocepacia|TrEMBL
MIRRMNKSAPSSWSALDAAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDR
INDVRQEKMARYLRANQRLDTHGAWDLYVDGAPDVSCSVKAYFALKAAGDSEHAPHMIRA
RDAILKLGGAARSNVFTRILLATFGQVPWRAAPFMPVEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNVSIRELFVTPPEEERRYFPPASGMRRLFLALDRTVRPIEPL
LPKRLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMQVLGYPDDHPLRRDCENAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVAAPETGDTATGAPRELDERIARA
YDWLATRQVNDLRGDWIENAPADVEPGGWAFQYANPYYPDIDDTALVTAMLDRRGRTHRA
ADGTHPYVSRVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVS
GRVLLCFGVTKRADDRASLARAIDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALAGE
DKSQPYITRALDWLRARQHADGGWGETNDSYIDPKLAGTNGGESTSNCTAWALLAQMAFG
DCESDSVKRGIAYLQSVQQEDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRL
VGAKDADATRSCASGASATPATDDALA
>U5DJB0|squalene-hopene cyclase|EC 5.4.99.17|Rubidibacter lacunae KORDI 51-2|TrEMBL
MQLHSEVWLGRLEEAVAASQRYLLSQQYPEGYWWAELEANVTVTVEVLLLHKIWRTDRLR
PLHKIETYLRQQQCESGGWEVFYGDGGDLSTSVEAYLGLRLLGVPAGDPALVKARTFILE
RGGISKTRIFTKFQLALVDCYNWRGLPSIPPWIVFCHPPFPFSIYEMSSWARCSTVPLAI
VFDKKPVYPVEPSVKLDELFAEGSANVRYELPRNNDWSDAFVWLDDAFKFAEDWNLVPLR
EEGLKAAERWIVERQEATGDWGGIIPAMVNSMLALRSLDYAVDDPIVDRGFQAIDNFVLE
DDEVYRVQSCVSPVWDTAWVVRALVDSGMAPDAPEVVAAGRWLLERQILDYGDWRVKNPQ
GEPGGWAFVFVNRYYPDIDDTAVVVIALEQLCLPEEALKRQAIARATQWIATMQCRAGGW
AAYDVDNDSDWLNLLPYSDLKATIDPNTADVTARVLEMVGYLDPQQPGIARERCDRALDY
LLDEQESEGCWFGRWGVNYIYGTSGALSALALVAPQRARNAIERGAAWLVGVQNPDGGWG
ETCRSYEDPTLKGKGVSTASQTAWALIGLLAAGDATGSYAQQFLARGVEYLLGTQLENGR
WEEAEFTGTGFPGHFYIRYHYYYQYFPLVALGRYRQFLAERT
>A0A520RAD8|squalene-hopene cyclase|EC 5.4.99.17|Parvularculaceae bacterium|TrEMBL
MFDDDAPATPSASPNSNFGAQLSQSITSAGDWLAARQNPDGYWVGRLESNACMEAEWCLA
LWFMGRDDDPLRERLAESLRVSQSDDGAWRIYHGAPAGDINTTVEAYAALRSVGDAPDAP
HMVRAREWILLKGGLTNIRVFTRYWLALIGEWPWAKTPNVPPEVIHFPSWFPFSIYNFAQ
WARATLMPIAVLSARRPSRPLPADRRLDELFPAGRTSFDYSLPDKPGTDGWDHFFRFADR
VLHIGQSLTENTGLDFGRNGSVSRALEWIIQHQDADGVWGGIQPPWIYSLMALYNEGYAF
DHPVMAKGLAALDDPRWRVDVGDATWIQASTSPVWDTVLTLLAYEDAELNDAHLEKVSDA
LDWILDQQVLRPGDWKVKAPTLEPGGWAFEYKNYFYPDTDDTAVALIALAPFRDDPSWKQ
KGIDTAIEKGVNWLFGMQSRNGGWGAFDKDNDKQILTKIPFCDFGEALDPPSVDVTAHII
EAFGKLGYSAAHPNIARALDYLKSEQEANGAWFGRWGVNYVYGTGAVLPALEAIGEDMGQ
QYIQKACDWLISKQNDDGGWGESCASYMDEKLIGVGKSTASQTAWALMGLVAVGREDDEK
AIAEGVQFLIDRQTADGTWDEPEYTGTGFPGYGVGQTIKLGDPLLEERLKQGAELSRAFM
INYNLYRHYFPLMAMGRIRKKLAV
>A0A3M8SMR7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces botrytidirepellens|TrEMBL
MTATTVQPSESSESETLVLARKATARAVQHLLSRQDEQGWWKGDLETNVTMDAEDLMLRH
FLGIQNPDVLDAAGRYIRSQQAADGTWATFHGGPPELSATIEAYVALRLAGDAPDAPHMA
AASAWVRNNGGVASSRVFTRIWLALFGWWRWEDLPELPPEIIYFPSWLPLNLYDFGCWAR
QTIVPLTIVSAKRPVRPAPFLLDELHADPRRPHPPRPAAPLASWDGAFQRLDRALHLYRK
VALRPLRRAALRSCARWIVERQENDGCWGGIQPPAVYSVIALHLLGYDLDHPVMRAGLES
LDRFAVWREDGSRMIEACQSPVWDTCLAVIALADAGLAPDHPALVKSADWMLAEQIDRPG
DWSVKRPRLAPGGWAFEFDNDNYPDIDDTAEVILALRRVDHPDPERIAAAVRRGVRWTLG
MQSRNGAWGAFDVDNTSPLPNRLPFCDFGEVIDPPSADVTAHVVEMLAHEGGARDPRTRR
AVAWLLAEQEPSGAWFGRWGTNYVYGTGSVVPALVAAGIPASHPAIRRAVRWLESVQNED
GGWGEDQRSYPDPEWIGHGTSTASQTAWALLALLAAGERESKAVERAVGWLAATQDQDGS
WDEPYFTGTGFPWDFSINYHLYRLVFPLTALGRYVSGEATGARPRRT
>F9ZFJ9|squalene-hopene cyclase|EC 5.4.99.17|Nitrosomonas sp. AL212|TrEMBL
MDGSQRISDMSQQPEGIAVSDEISSAYSVSSLNQDEINVDELENKLTQARSAMLSLQKPD
GHWCFPLEADCTIPAEYILMMHFMDEIDVILENKIARFIREKQDLTHGGWPLYYGGAFDI
SCTIKSYYALKLVGDSPDAAHMVRAREAILERGGAAKANVFTRLLLAMYEQIPWSGVPVV
PTELMLLPSWFPFHISKVSYWSRTVMIPLSILCTIKARAINPRNVDIRELFIVPPEQEKN
YFPQADTWLKRAFMLVERVLSRVEPKLPQAIRQYSIRKAENWTLERLNGECGIGAIFPAM
VNAHESLALLGYAYDHPSRVQCRNALRGLLVDEGERAWCQPCTSPVWDTVLTCLALQEDP
AADQGPVLKALDWLVDQQVLDEPGDWRDKRPDLLGGGWAFQYANPHYPDLDDTAAVAWAL
DQSDAQRYQKPLDRAANWLAGMQSRNGGFAAFDIDNTYHYLNEIPFADHGALIDPPTSDV
TARCVGLLGKYGKHQREVWRGISFLLREQEKNGSWFGRWGTNYIYGTWSVLEAFQLANFD
MQHTSVRRAVKWLESVQRVDGGWGETNDSYLDIQLAGQFPQTSTTFQTAWAVLGLMAAGE
VNSKSVRRGINYLLHNQADDHLWEDPWFTAPGFPRVFYLRYHGYSKFFPIWALVRYRALT
KERVS
>A0A7Y7RIS1|squalene-hopene cyclase|EC 5.4.99.17|Pseudomonas sp. B6002|TrEMBL
MNPRLECAIEDALNALLLRQRPDGHWVFELETDAAMTAEYVLQMHFLGEPIDPILGAKLA
RYMSDLQQPEGGWPVLQGGHFDLSTSVKTYFALKLLGRAENEQPLQRACALIRQHGGAAG
SNVMTRIWMALFGFIPWHALPSVPVEVILLPRWFPFHLSKIACLPRKYTVAFSVLHVSRP
IARNPQRTSIAELFLEPPEQTRPLRCAPHQNKAWFALFGGIDRLLHRCTPWFPKGLRQKA
IDRAVSSVIAQLNGEDGYGATLPTIGASVILLRALNYPDDHPAVLTARKARDKLLVIHPQ
AAYCQPCVSPIWDTAWVCQALLETGEKRGIESASHGLKWLRYKQILDTYGDWVMTRPDLR
PGGWAFQYNLPRHPDVDDTAVVATVMQRALCTNPTADYGEAISRAREWVEGMQNRQGGWG
AYEAENTQNYLNSFPIAEHGLMIDFPSADVSARCLCMLGLLEATPATRHVTDKALHYLLA
QQEADGSWYGRWGINFIYGTWSALEGLATNGHDPQFPAVRRAREWLIKHQNSDGGWGENA
SGYALKRQGHQPSESTPSQTAWALLGLMVAGAVNHPATRRGIAYLQQSQHHDGTWTDGHA
TGTGIPRAMYLHYHGYAVYFPLWALARYRNLTIEED
>A0A372LFW8|squalene-hopene cyclase|EC 5.4.99.17|Peribacillus glennii|TrEMBL
MKRAVISEMNRLIAKLINDQSHDGSWDYAFETGISTDSYMIILLRSLEIHDDKLIQALVK
RILSKQESNGAWKLYHDEGSGNMPATLEAYYGLLYSGYINKKDPRMRAARQFILREGGIE
KAGMFTKVLLSLTGQSPWPAIFPVPIEIFLSPIPLPVNFYDFSVYARANLTPILIVGNKK
FQLKTDHSPDLSDLYVNRLQNNEDEPFFRSDDVNEWRNLITVLKEGMKSLTGFSEHLRTA
AFDKAKQYMLGRIEPDGTFYSYFSSTFLMIFALLSLGYPKHHSTIKKAVQGLKSMACEID
GHVHMQYTTADVWNTSLISYALQEAGVPKSAESIQKANQYLLSRQHSKYGDWVVHNPDTL
PGGWGFSNINSFNPDVDDTTASLRSIRHMAGRLPEYSGAWGRGINWVFSMQNKDGGWPAF
ERNVDKKLLNLVPVQGAEFTLLDPSSADLTGRTLEFLGNHTNLNKNHPSLKRGRNWLSSH
QERDGSWYGRWGICYIYGTWAAVTGLIASGKRPESAVIQNAAAWLRLIQNEDGGWGESCH
SDTEKKYVPLGESTLTDTAWAIDALIAASDTPTPEIQAGIKYLIENGNRQDWTEQYPKGQ
GMGGAFYIHYHSYRYIWPILALSHYRKKFLTEKQ
>A0A846F3F8|squalene-hopene cyclase|EC 5.4.99.17|Okeania sp. SIO1H5|TrEMBL
MTEKNKVQQSILASQEYLLNLQKPQGYWWDELESNVTITAEIVLLHKIWQTDKKRPLDKA
KNYLISQQREHGGWELFYGDGGDLSTSIEAYMALKLLGVAKTDPSMLKAQDFIIKKGGIS
CSRIFTKLHLALIGCYNWQGIPSIPPSIMLLPEDFPFTIYEMSSWARSSTVPLLIVFDKK
PIFSVNPTINLDELYAEGINNASFELPRQYDLTDLFLGLDKAFKFAENFNLMPLREEGLK
AAEKWILERQEVTGDWGGIIPAMLNSMLALRCLEYDVADPVVVRGLEAIDRFGIETEDSY
WVQPCVSPVWDTAWVIRSLVDSGIPPRHPAVVKGGEWLLQQQILDYGDWAVKNKLGKPGG
WAFEFINRFYPDIDDTAVVVMALDAVELPDEELKRVAIARAMEWVASMQCQPGGWAAFDV
DNDQDWLNGIPYGDLKAMIDPNTADVTARVLEMVGCCGLSMDSWRMKRAIAYLEREQEGE
GCWFGRWGVNYIYGTSGVISALAVVAQESHRDFIEKGASWLVGCQNSDGGWGESCWSYND
PSLKGKGKSTASQTAWALIGLLAAGEATGNFAREAIDRGVDFLVSTQNDDGSWLESEFTG
TGFPCHFYIKYHFYPQYFPLMALGRYENLLSG
>A0A370WTD9|squalene-hopene cyclase|EC 5.4.99.17|Dyella monticola|TrEMBL
MNPFTPTTATAATAELFQSTQPGSLDEAIERGRVALLAQQHRDGHWCFELESDCTITAEY
ILMMHYMDEIDDVLQAKLARYLRATQVKDGHGGWPQYHGGDIDLSCTIKGYYALKAAGED
PEAEHMRIARKAVLAHGGAAKANVFTRILLALFEQVPWRATPYVPVEIMLLPRWFPFHID
KISYWARTTLVPLTILCSLKAKAANPRKVHIRELFVTPPEQERHYFRRGGLLNRTFLVLD
KIGRVADRFIPKAVRQRAVKRAVDWFVPRLNGEDGIGAIFPPMVNSLEAMTLLGYPKDHP
ARQTCLRSIQKLVVHRADGSAYCQPCVSPIWDTVWSALTLMHTSDDAHTQSAIDKSIDWL
TSKQELELQGDWAVRAPDLKPGGWAFQYNNAYYPDIDDTAVVAALLHIQDRRRGESGRHR
LNTDRAMDWMIGLQSKNGGFAAFDADNTYYYLNAIPFADHGALLDPPTEDVSGRVVAALG
VLGRPQDREALRRCVDYLRSTQLEDGSWWGRWGSNYIYGTWSVLAGLALAGEDPQQPYIR
KSVDWLRARQHADGGWGETCDSYIDPELRGRNQGISTPQSTAWALLAQMAVGEVRSESVR
RGVAFLLAKQQAEGLWFHPSHNAPGFPRVYYLKYHGYTAYFPLWALSRYRQLLPLAKA
>A0A534I8P9|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MQPCAPALASGRLEWPVRRELATVTRGSPTRGSSAVAPNAARADAPAHKIHRLTEFSPLD
RSIAAARDALISLQSSQGYWLFELEADCTIPAEYVLMTHFLDEIDASLEPKLAAYLRARQ
AEHGGWPLYHGGDFDMSCSVKAYFALKLAGDSPQAPHMVRARAAILQRGGAARCNVFTRI
TLALFGQLPWRGVPYIPVEIVLLPRWFPFHLDKVSYWSRTVMVPLLILCTRQPAASNPRK
VQIRELFTTPPEEERHYFRRPGGRQGVLSRAFLALDRLGRMIDPLIPKALRAYATRRAEA
WMLERLNGEHGLGAIFPAMVNALEALAVLGYATSDAPRVAAKRALEKLLVVNASSAYCQP
CVSPVWDSALASLALQETGGAAALAASVRALDWLQPLQLLDNPGDWRVRRPQLAGGGWAF
QFWNAHYPDLDDTAVVAWSMHQAGDLARYAHNVQCALDWLVGMQSHNGGFASFDVDNTHY
YLNEIPFADHGALLDPPTSDVTARVVTVLARVGRPQDQAVLARAIAFLRQEQEADGSWFG
RWGTNYIYGTWSVLTAFAQAGIGPDDPATRRAVSWLTARQNADGGWGESNDTYAYGQLAA
GKSPSVPHQSAWALLGLLAAGEAGTDAVRRGVEYLLRTQQDDGLWSDPSFTAPGFPRVFY
LRYHGYCAYFPLWALAAYRTLIRLGTTH
>A0A534CLN6|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MEELDPADYAICAARDALIGRQSSQGYWLFELEADCTIPAEYILMMHFLGEIDAPLERKI
ATYLRARQGRHGGWPLYHGGDFDMSCSVKAYFALKLAGDSPEAAHMQRARAAILGRGGAA
RSNVFTRITLALFGDVPWRGVPYIPVEIMLLPRWFPFHLQKVSYWSRTVMVPLLILCTRK
PVASNPRRVHIRELFTTPPERERHYFRRPGGQADLLAKTFLLLDRLGRLTDPLIPAAVRE
RATRRAEAWMLERLNGEQGLGAIFPAMVNALEALAVLGYRSDDPRRVTAKRALEKLLVVN
ASSAYCQPCFSPVWDTALASLALQETGGPAALAASAKALDWLRSQQLLEQPGDWQARRPG
LAGGGWPFQFANPHYPDLDDTAAVVWSMDQARDPGHYLPNVSRALDWLVGMQSADGGFAS
FDADNTCYYLNEIPFADHGALLDPPTADVTARVVTVLARVGRPGDQAALARAIAYLRAEQ
EADGSWFGRWGTNYIYGTWSVLTAFAHAGVGADDPAVQRAVAWLKERQNADGGWGESNDT
YAQQSSVGGNSPSSPYQSAWALLALLAAGDGRSEAVRRGIEYLWRTQQADGLWSDPSFTA
PGFPRVFYLRYHGYSAYFPLWALAAYRNLARLGTSH
>A0A534GJZ7|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MDFGNSDERYQEEILPHVSRTFALTIPQLPPGLRTAVTNAYLLCRIADTIEDEPAVSPEE
TFQFLERLAAVVSGAKDPAALACALDGRFSDRTLPAERDLVSNLERIVRVTWGLGAQRAA
IERCIALMCRGMHEFQRSASIRGLPRSSDLDGYCYYVAGVVGEMLTELFCAYSPAVAARH
DALAELSVSFAQGLQMTNILKDFWEDRSRGACWLPQETFARHGVVLAELSPGRTGAGFGA
GLSELIGVAHAHLRNALAYTLLIPRTEPGIRRFCLWALGLAVLTLRRIAANPAYTSGAEV
KVSRPVVWLTRISTSLVVGDNRGRIPAGERGRRGAGSLRPELAAAGPVSRKAGTSAALAG
TEGLLRADAPARKLPGEKLSPLEYAIAAARDELIRLQRPDGSWQLELEADCTIPAEYIMM
MHFLGELDPALEAKLAAYLRQRQAGYGGWPLYHGGAFDMSCSVKVYFALKLAGDDPESPH
MARARAAILERGGAAACNVFTRIALALFGQLPWRGVPYIPVEIVLLPRWFPFNIHRVSYW
SRTVMVPLLILCTLKPRAKNPRNVDIRELFTTPPGQERRYFRRPLGGSATLARAFFCLDR
LARSLDGLIPRALREHALERAEAWMLERLNGEEGLGAIFPAMVNALEALSVRGYSPDHPH
RRGAKRALEKLLVEDYSSAYCRPCVSTVWDTALAGLAMQEEGSAGARAAALRGLEWLEPR
QLLDEPGDWRTRRPHLPGGGWAFQRANSYYPDLDDTAAVAWSMHRSTDPGRFSFALSRAL
DWLVGMQSENGGFASFDVDNTSYYLNEIPFADHGALLDPPTSDVTARVVTALARVGRPED
RGALTRAIDYLRREQEANGSWFGRWGTNYVYGTWSVLSAFAEARIGPDDPAVERAVSWLE
SRQNPDGGWGESNDSYEPGRAGASAPSTPHQSAWAVLALIAAREAGSDAVRRGIEYLLRT
QRPDGLWSDPSFTAPGFPRVFYLRYHGYCAYFPLWALAAYRNSTAAGPGTVH
>A0A7S6SA87|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MDGFQRIADVSQQRDDFTVSGETPELHTASTLHQDGIDAAELETKFAQAHAAMLALQNAD
GHWCFPLEADCTIPAEYILMMHFMDEIDVILENKIARFIRDKQDMTHGGWPLYYGGAFDI
SCTIKSYYALKLAGDSPDAPHMARAREAILHYGGAAKANVFTRLLLAMYDQIPWHGVPVV
PTELVLLPSWFPFHISKVSYWSRTVMIPLSILCTLKARAINPRKVDIRELFIVPPEEEKN
YFPKADTLLKRAFMLVERVLSRVEPKLPQSIRQYSIRKAERWTLERLNGECGIGAIFPAM
VNAHEALTLLGYGYDHPNRVQCRNALRGLLVDEGERMWCQPCTSPVWDTVLTSLALQEDP
TTDQEPVLKALDWLVEQQVLEEPGDWRDKRPDLPGGGWAFQYANPHYPDLDDTAAVAWAL
EQGAAERHHKSLERAANWLAGMQSRNGGFAAFDIDNVHHYLNEIPFADHGALIDPPTSDV
TARCVGLLGRYGKHQREVWRGISFLLLEQEKDGSWFGRWGTNYVYGTWSVLEAFRLAKFD
MQHHSVRRAVKWLESVQRVDGGWGETNDSYLDTQLAGRFPETSTAFQTAWAVLGLMAAGE
VHSESVRRGIQYLLHNQSNDHLWEEPWFTAPGFPRVFYLRYHGYSKFFPIWALARYRTLT
REITN
>A0A534B414|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MSRKAGTSAALAGTEGLLRADAPARRLPGEKLSPLESAIAAARDELIRLQRPDGSWELEL
EADCTIPAEYIMMMHFLGELDSALEAKLAAYLRQRQAGYGGWPLYHGGAFDMSCSVKVYF
ALKLAGDDPESPHMARARAAILERGGAASCNVFTRIALALFGQLPWRGVPYIPVEIVLLP
RWFPFNIHRVSYWSRTVMVPLLILCTLKPRARNPRNVDIRELFTTPPGQERRYFRRPLGG
SAALARAFFSLDRLARSLDGLIPRALREHALERAEAWMLERLNGEDGLGAIFPAMVNALE
ALSVRGYSPDHPHRRGAKRALEKLLVEDYSSAYCRPCVSTVWDTALAGLAMQEEGSAGAR
AAALRGLEWLEPRQLLDDPGDWRTRRPHLPGGGWAFQRANSYYPDLDDTAAVAWSMHRST
DPGRFSFALSRALDWLVGMQSENGGFASFDVDNTSYYLNEIPFADHGALLDPPTSDVTAR
VVTALARVGRPEDRVALTRAIDYLRREQEANGSWYGRWGTNYVYGTWSVLSAFAEARIGP
DDPAVERAVSWLESRQNPDGGWGESNDSYEPGRAGASAPSTPHQSAWAVLALIAAREAGS
DAVRRGIEYLLRTQRPDGLWSDPSFTAPGFPRVFYLRYHGYCAYFPLWALAAYRNSTAAG
PGTVH
>A0A4Y6V6I6|squalene-hopene cyclase|EC 5.4.99.17|Neokomagataea tanensis|TrEMBL
MSETLVREKTDDATINTAAVERAITSAHQALGGRQKADGHWIFELEADATIPAEYVLLEH
YLDRIDTERQAKIGVYLRRIQGKHGGWPLYHDGGFDLSASIKAYFALKAIGDDIDAPHMA
RAREAILDHGGAARSNVFTRFQLALFGEAPWSATPVMPVELMLLPRKAFFSLWNMSYWSR
TVIAPLLVLAALRPKAINPHKVSVRELFVQPPEDVKDWNLGPFRSKWGHVFKHVDTVLRP
IVPRIPRKIHDKAIQAAIDFIEPRLSKGGLGAIYPAMANVVMMYRALGVPDNDPRVETAW
QSIHDLLVEKEDEIYCQPCVSPVWDTGLSGLAMMEAATGPRATKRDETIEALKRSASWLR
DRQILDVKGDWIVNTAPDLRPGGWAFQYENDYYPDVDDTAVVGMLLHRLDPEGNKEAIER
AREWIIGMQSTNGGWGAFDIDNDMDFLNHIPFADHGALLDPPTADVSARCVSFLAQLGHT
EDRPTIERALAYLRQEQEEDGSWFGRWGTNFIYGTWSVLCALNIAGIPHSDPMIQRAVAW
LKRMQREDGGWGEDCASYEGAASGQYKESLPSQTAWAVLGLMAVGERDSDAVKNGIQFLA
QAQDEHGEWHEEPYNAVGFPKVFYLRYHGYKQFFPLTALARYRNLGDSNTGRVEVGF
>A0A7S7T7X1|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. CCBAU 51765|TrEMBL
MDSVNATSRETLESSIASAREGVLGFQQPDGHWVFELEADCTIPAEYILLRHYLAEPVDA
VLEAKIGNYLRRVQGDHGGWPLVHEGEFDMSASVKAYFALKMIGDSVDAPHMVRAREAIH
ARGGAINSNVFTRFLLATFGVVTWRAVPVLPIEIVLLPFWSPFHLNKISYWARTTMVPLM
VIAALKPRAKNPLGVGIDELFLQDPRSIGMTAKAPHQSMAWFLLFRSLDAILRVIEPLFP
KRLRKRAIDAALAFIEERLNGEDGMGAIYPPMANIVMMYDALGKDENYPPRAITRRGIDK
LLVINDDEAYCQPCVSPVWDTTLTAHALLEAGDAQAVPAAKRGLDWLIPKQELEVKGDWA
VKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGVAGYDTAIARGREWIEGMQ
SDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETATTSKQVAA
GVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDHKDPMIRKAAAWLASIQNED
GGWGEDAVSYRLDYRGWQAAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIATQNKKG
LWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A1R4H034|squalene-hopene cyclase|EC 5.4.99.17|Crenothrix polyspora|TrEMBL
MINDNTHESLSDNLGSATPIRSNKYHLDTAIQHAQDKLLSLQDKNGFWVFELEADCTIPS
EYIMMMHYVGGIDTDLQAKIAVYLRSRQAKDGSYPLFTGGTGDLSCSVKVYYALKMAGDA
IDAPHMLRLKAYILAQGGAAKANVFTRITMAIFEQVPWRAVPYIPAEIMLLPKWFPFHLD
KVSYWSRAVMVPLFVLCTLKATAKNPHKVNILELFVTHPDEEQHYFQKGTLLNKVFLGLD
KLGLAINPLIPNSVRQHALGKAKDWITERLNGEDGLGCIFPAMVGAYEALMLLGVPEDHP
DVVTARKAIDRLLVINEHDAYCQPCFSPVWDTGLAALALQEADEKANSKALTHAYNWLKS
KQLSDEPGDWRIARPDLAGGGWAFQYANPHYPDVDDTAMVAVAMACSNLPDLDESVHRAT
NWIVGMQSKNGGYGAFDVDNTCYYLNSIPFADHGALLDPPTADVSARCAMLMARLATKHA
QYRPALERTLAYLRSDQEADGSWFGRWGTNYIYGTWSVLIALEQTDMVKTDPMYTKAAAW
LKSVQRDDGGWGEDNNSYHDASLSGQYGFSTAFQTAWAVLGLIAAGEVHSQEVKAGIDFI
LRNQQADGVWNDKCFTAPGFPKVFYLKYHGYDKFFPLWALARYRNALDKK
>A0A7W3RPK0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces murinus|TrEMBL
MTATTDGSTGATLPSRAAAASDTTLTTPEAAGAPEAAAQAARRATDFLLSRQDAEGWWKG
DLETNVTMDAEDLLLRQFLGIQDERTTQAAAKFIRGEQREDGTWATFWGGPGELSTTIEA
YVALRLAGDAPDAPHMARAAAWIRERGGIAAARVFTRIWLALFGWWKWEDLPEMPPELIW
FPGWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPANPNPPKPLAPANT
WDGAFQRLDRALRQLRKVVPRRLRKAAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVLREGLASLDRFAVWREDGARMIEACQSPVWDTCLAAIALVDAGLPVDHPQ
LVKAADWLLGEEIVRPGDWAVKRPQLPPGGWAFEFHNDNYPDIDDTAEVSLALRRIRHHD
PERTDRAIGRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAAEGLAHDPRTRRGIAWLLAEQEQNGAWFGRWGVNYIYGTGSVVPALTAAGLPASH
PAIRRAVTWLESVQNDDGGWGEDLRSYKHVREWAGRGASTPSQTAWALMALLAAGEKDSK
AVERGIQWLAATQREDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFER
QLLARTPRPRPEAAKPTGSPLSEAKGS
>A0A3P0XAB3|squalene-hopene cyclase|EC 5.4.99.17|Acidipila sp. EB88|TrEMBL
MSTAPQQEQLGNQGSRLRFGRLDVALDSVESAIGRVRDWLFSQQHPDGYWCGELEADSLL
EADYIFGHMLLGTGDPARLERALAEMMRTQGEDGSWANYPGGPGNISVSVKCYFACKLMG
WSQDEPRLVRAREWILANGGVVECNTFTKIYLCFMGQYEYDAVPAVPPEIVLFPNWFYFN
IYEISSWSRAILVPLSIAYAKKPFKKIAPEQGIDELFVGGRENANLHLRWDREKPVSWRN
FFLLTDRLTHWAERVHIRPLRRMALKRAEKWMLARLELSDGLGAIYPAILNSMIALRWLG
YSIDDPQMIRASDEFEKLGIDAPEGTADYAEPTFRMQPCVSPVWDTAQAVFALGEAGVER
TDPRMLKAVDWMLSKEVRHKGDWAEKVRNTEPGGWYFEFANEWYPDVDDTAQVLLALNKV
DNPRERYQYDVSKRALDWIFAMQCRNGGWASFDKDNTKMIFQYIPFADHNAMLDPPTVDI
TGRVLETLSTYGYTRSDKRIERAIKFIFDEQESDGSWFGRWGVNYLYGTFLVLRGLEAIG
IWNHEPQIQQAAEWIRMVQNADGGWGESCLSYDEPDLRGVGASTPSQTAWAVLGLLSAGD
KRSDSVAKGVRWLLEHQAESGGWDESTDAATQKQAVYTGTGFPRVFYLAYHLYRDYFPLL
ALTTYKRAIERGDE
>A0A838TD71|squalene-hopene cyclase|EC 5.4.99.17|Chthoniobacterales bacterium|TrEMBL
MGNPSANIITLPRPAKESAPRLTTNEELTEAIGQAQQNLLRQQKPDGHWVGELMVDSTLC
SDYVLFMHWLGEVDETLQRRCAKHILKRQLPDGGWNIYYGGPSEINACVKAYFALKLAGH
SPDAPFMQEARANILRLGGVPRMNTYSKLYLALLGQFPWKYLPVIPVEMVLLPSWCFFNI
YKMSSWSRAMLIPLAIINHFKPTRELPANKQLHELYPVGTEGNDFTLARDQRMLTWRNFF
LRADRALKLLERWHSRPLRQRALEEAERWMVERIGEGSDGLAAVFPAMLNSIIALRTLDY
PASHPLYQKALTDFRGLFVNDPEDFRIQPCLSPVWDTAINIIALAESGFPAQHPALQQAA
QWLVDKEVRVRCDWTSNNPHPEASGWAFEYNNVFYPDTDDTAMVLMALRLVRPSEQARLA
EVFNRALDWQLSFQCRDGGWAAFDRDVTRHWLEDMPFADHNAILDPTCSDLTARTLELLG
YIGFNPGRPLVRRAVRYLRETQEDDGSWYGRWGVNYIYGTWQVLRGLRAIGEDMTEDWIL
RGRDWLESCQNDDGGWGESCASYENPDLKGKGASTASQTAWALMGLCACGDLDRPSVQRG
LRYLLDTQRSDGAWDELEITGTGFPRVFYLKYDMYRQNFPLLALATYVNYRSGVGHYQSF
YRWVGK
>A0A3N8QHY2|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia contaminans|TrEMBL
MIRRMTTATPSPWSALDTAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDK
IDDIRQEKMARYLRANQRLDTHGGWALYVDGDPDVSCSVKAYFALKAAGDSEHASHMIRA
RDAILKLGGAARANVFTRILLATFGQVPWRATPFMPVEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNISIRELFVTPPDEERQYFPPARGMRRLFLALDRTVRHVEPL
MPKGLRQRAIRHAEAWCAERMNGEDGLGGIFPPIVYANQMMQVLGYPDDHPLRRDCDNAL
EKLLVTRPDGSMYCQPCLSPVWDTAWSTMALEQARGVAVAADGESGDARRALDERIARAY
DWLAERQVNDLRGDWIENAPADVQPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRTHANA
DGTNPYAPRVARALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRAEERASVARCIDYVKRTQQPDGSWWGRWGTNYIYGTWSVLAGLALAGED
KSQPYIARAIEWLRSRQHADGGWGETNDSYIDPKLGGTNGGESTSNFTAWALLAQMAFGD
CESDSVKRGIAYLQSVQQEDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GAAAARASAEHGATAVKATDSVVA
>A0A372LYV1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces triticagri|TrEMBL
MTATTDGSTGAVPPHAPSAKESTGEAPTALDAARRATALATDFLLSRQDAQGWWKGDLDT
NVTMDAEDLLLRQFLGIRDEHTTQAAALFIRGEQRDDGTWATFYRGPGELSTTIEAYVAL
RLAGDAPDDPHMAKASEWIRAQGGIARSRVFTRIWLALFGWWKWDDLPELPPELIYFPKW
FPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAVPRPPEPLAPVASWDGV
FQRLDKALHAYHKVAVPGLRRAAMRSAARWIVERQENDGCWGGIQPPAVYSVIALHLLGY
DLEHPVLRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATVALADAGVPADHPQLVRA
ADWMLAEQIVRPGDWSVRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVAHPDRKRV
DAAIARGVRWNVGMQSRNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVTGHVVEML
AYEGRAHEPAARRGIEWLLAEQEPNGAWFGRWGVNYLYGTGSVVPALTAAGLPASHPAIR
RAVDWLESVQNDDGGWGEDLRSYIDSAWVARGESTASQTGWALLALLAAGERESKSVQRG
VAWLAETQLADGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGTGHEGA
>A0A380P662|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces griseus|TrEMBL
MTATTNGPAGAAPSRPAPARPTTDTTTAPDSATVEAAAERARARAADHLLGLQSPEGWWK
GDLDTNVTMDAEDLLLRQFLGIRDEATTRAAALFIRGEQREDGTWATFHGGPPDLSTTVE
AYVALRLAGDSPDAPHMTRAAHFVRARGGIAEARVFTRIWLALFGWWPWDRLPELPPELI
FLPPWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPANPAPRTRLAPLA
SWNGAFQRLDRALHTYRKVAPRALRRAAMAAAGRWIIERQENDGCWGGIQPPAVYSMIAL
HLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALADAGVPADHP
QLVRAADWMLDEQIERPGDWSVRRPHLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHP
DTARLERAISLGVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDPPSADVTAH
VVEMLAAEGLGADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALIDAGLPAT
HPAIRRAVAWLESVQNDDGGWGEDLRSYRDQGRMARGASTASQTGWALMALLAAGERESA
AARRGVAFLADTQHEDGSWDEPYYTGTGFPWDFSINYHLYRQVFPLTALGRYTRGAAPEA
A
>B3RCD7|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CCUG 44338 / CIP 107171 / LMG 19424 / R1)|TrEMBL
MNETAFANPAPQVGPAQRQPAAPQEAPAARLPAPALDRGIDRALDALLHQQRPDGHWVYE
LEADATIPAEYVLMVHYLGEDPDRDLEARIARYLRRIQNPDGGWPLFHQGRSDISASVKA
YFALKMAGDDPQSAPMQRARQAIHAMGGAEATNVFTRTLLALYGVLPWKAVPMMPVEIML
LPRWFPFHLSKVSYWARTVIVPLLVLNSLRPQARNPRGVGINELFVGNCHTVGLPPRAAH
QHAGWYTVFRGLDALLRLAEPLFPRTLRRRAIAAAQRFVRERLNGEDGLGAIFPAMANSV
MMFDVLGVPPEDPARAVARRSIERLLVEHGDEAYCQPCLSPVWDTALATHALLETGEARA
AQAAGRALDWLRPLQVLDLRGDWAVRRPLVRPGGWAFQYANAYYPDVDDTAVVAAAMDRF
MRAHHAPGRYGEAVARATEWIVGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDPPTA
DVSARCLSMLCQTGATPANSEPAARALRYLLAEQMPDGSWFGRWGTNYIYGTWSALCALN
AAGLPPEAPELCRAVAWLARIQNADGGWGEDGSSYRLDYSGYEPAPSVASQTAWALLALM
AAGAAQHPAVARGIDYLLRTQQPGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWALARY
RNLQRGLGDHGGNSGQVAWGL
>A0A7K3D5F5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID337|TrEMBL
MTATTDGSTGAATPRAASASQSTETVLPIDTTAAGPREAAARAMRRSTDFLLARQDAEGW
WKGDLETNVTMDAEDLLLRQFLGIRDEDTTRAAALFIRGEQRDDGTWATFYGGPGELSTT
IEAYVALRLAGDRPDEPHMAKASAWIRDRGGIAEARVFTRIWLALFGWWKWDDLPELPPE
LIYFPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDARVPNPSKPLAC
VASWDGVFQRLDKALHVYHKVAPRPLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVI
ALHLLGYDLEHPVLKAGLASLDRFAVWREDGSRMIEACQSPVWDTCLATIALADAGVPAD
HPQLVKAADWMLGEQIVRPGDWSVRRPGLTPGGWAFEFHNDNYPDIDDTAEVALALRRVA
HPDKARLENAIDRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVT
GHVVEMLAVEGKSHDPRTRRGIEWLLAEQEENGAWFGRWGVNYIYGTGSVVPALITAGLP
ASHPAIRRAVRWVESVQNDDGGWGEDLRSYRDRGWVGHGTSSASQTAWALLALLSAGERE
AKSTERGIAWLVDAQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYINGEPF
AGGSDARTAKGS
>C7CHV9|squalene-hopene cyclase|EC 5.4.99.17|Methylorubrum extorquens (strain DSM 6343 / CIP 106787 / DM4)|TrEMBL
MREAAVSKVETLQRPKTRDVSLDDVERGVQSATRALTEMTQADGHICFELEADATIPSEY
ILFHQFRGTEPRPGLEAKIGNYLRRTQSKVHGGWALVHDGPFDMSASVKAYFALKMIGDD
IEAPHMRAVRKAILQRGGAANANVFTRILLALYGEVPWVAVPVMPVEVMHLPKWFPFHLD
KVSYWARCTMVPLFVIQAKKPRAKNPRGVGVAELFVTPPDSVRTWPGSPHATWPWTPIFG
GIDRVLQKTQDHFPKVPRQRAIDKAVAWVSERLNGEDGLGAIFPAMVNSVLMYEVLGYPP
EHPQVKIALEAIEKLVAEKEDEAYVQPCLSPVWDTALNSHAMLEAGGHQAEANARAGLDW
LKPLQILDIKGDWAETKPNVRPGGWAFQYANPHYPDLDDTAVVVMAMDRAQRQHGLVSGM
PDYSESIARAREWVEGLQSADGGWAAFDADNNHHYLNHIPFSDHGALLDPPTADVTARVV
SMLSQLGETRATSRALDRGVTYLLNDQEKDGSWYGRWGMNFIYGTWSVLCALNAAGVDPQ
SPEIRKAVAWLIRIQNPDGGWGEDASSYKLNPEFEPGYSTASQTAWALLALMAAGEVDDP
AVARGVNYLVRTQGQDGLWSEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKRGNS
RQVQFGM
>A0A375D342|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus taiwanensis|TrEMBL
MSMNETALANAAPHTDAAQREPAGPAQAPATRLSAPALDHGIGRALDALLHQQRPDGHWI
YELEADATIPAEYVLMVHYLGEAPDLDLEARMARYLRRIQNPDGGWPLFHQGRSDVSASV
KAYFALKMAGDDPQSAPMQRARQAIHAMGGAEATNVFTRTLLALYGVLPWKAVPMMPVEI
MLLPRWFPFHLSKISYWARTVIVPLLVLNSLRPQARNPRGIGINELFVGNCHTVGLPPRA
PHQHAGWYTVFRGLDALLRVAEPLLPRTLRRRAIAAAQRFVRERLNGEDGLGAIFPAMAN
SVMMFDVLGVPPDDPARAVARRSLERLLVEHGDEAYCQPCLSPVWDTALATHALMETGEV
RAAQAAGRALDWLRPLQVLDLRGDWAVRRPLVRPGGWAFQYANAYYPDVDDTAVVAAAMD
RFMRAHDAPGRYGEAVARATEWIVGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDPP
TADVSARCLSMLCQTGATPRKSEPAARALRYLLAEQMPDGSWFGRWGTNYIYGTWSALCA
LNAAGLPPAAPELQRAVAWLARIQNADGGWGEDGSSYRLDYRGYEPAPSVASQTAWALLA
MMAAGAAQHAAVARGIDYLLRTQQPGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWALA
RYRNLQRGHADHRGHSGQVSWGL
>A0A3N6N4T7|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia dinghuensis|TrEMBL
MPTEDLASGVATAADSTPADPLAHTAATDGAAAPVDALDESIARATDAILAAQQADGHWV
YELEADATIPAEYVLLVHYLGETPNLELEQKIARYLRRIQLPDGGWPLFAEGAMDVSASV
KAYFALKMIGDAPDAPHMVRAREAILAAGGAESVNVFTRILLALFGVVTWYAVPMMPVEI
MLLPQWFPFHLSKVSYWARTVIVPLLVLNAKRPVARNPRGVRIDELFHRAPVTTGLNKRA
PHQSKGWFSFFRAVDSVLRVADPLLPNYLRQRSIDAAVAFVDERLNGDDGLGAIFPAMAN
SVMMYDVLGYPADHPHRAIARQSVEKLLVIHEDEAYCQPCLSPVWDTSLAAHALLETGEA
RAEEAARRGLEWLRPLQILDVRGDWISRRPDVRPGGWAFQYANPHYPDVDDTAVVALAMH
RVDKLDNTNSYDESIARAREWVVGMQSSNGGWGAFEPENTQYYLNNIPFSDHGALLDPPT
ADVSGRCLSMLAQIGEIPSASEPARRAYNYLLEEQEADGSWYGRWGMNYIYGTWTALCAL
NAAGLPHDDAHMKRAVQWLVKIQNEDGGWGEDGTSYKLEYRGYERAASTASQTAWALLGL
IAAGEVNHPAVARGIEWLQKTQCEHGLWDETRFSATGFPRVFYLRYHGYRKFFPLWALAR
YRNVKRSGTTLVTVGL
>A0A6L7H1K5|squalene-hopene cyclase|EC 5.4.99.17|Bacillus anthracis|TrEMBL
MLLYEKAHEEIVRRATALQTMQWQDGTWRFCFEGAPLTDCHMIFLLKLLGRDKEIEPFVE
RVASLQTNEGTWKLHEDEVGGNLSATIQSYAALLASKKYTKEDANMKRAENFIQERGGVA
RAHFMTKFLLAIHGEYEYPSLFHLPTPIMFLQNDSPFSIFELSSSARIHLIPMMLCLNKR
FRVGKKLLPNLNHIAGGGGEWFREDRSPVFQTLLSDVKQIISYPLSLHHKGYEEIERFMK
ERIDENGTLYSYATASFYMIYALLALGHSLQSSMIQKAIAGITSYIWKMERGNHLQNSPS
TVWDTALLSYALQEAQVSKDNKMIQNATAYLLKKQHTKKADWSVHAPALTPGGWGFSDVN
TTIPDIDDTTAVLRALARSRGNKNIDNAWKKGGNWIKGLQNNDGGWGAFEKGVTSKLLAK
LPIENASDMITDPSTPDITGRVLEFFGTYAQNELPEKQIQRAINWLMNVQEENGSWYGKW
GICYLYGTWAVMTGLRSLGIPSSNPSLTRAASWLEHIQHEDGGWGESCHSSVEKRFVTLP
FSTPSQTAWALDALISYYDTETPAIRKGVSYLLSNPYVNERYPTGTGLPGAFYIRYHSYA
HIYPLLTLAHYIKKYRK
>A0A3G3LDL9|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia gladioli|TrEMBL
MIRPMKNSDLPLPSMLDAAILRGRDALAQRQNADGSWCFELESDATITAEYILMMHFMGK
IDDARQARMARYLREIQRLATHGGWDLYVDGAPDVSASVKAYFALKAAGDSEDAPHMARA
RDTILRLGGAAKCNVFTRILLATFGQVPWRATPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARAKNPRGISIRELFVTAPEDERNYFARGGFVRNLFLGIDRTLRPLDAL
IPKALRRRAIRHAEAWCAERMNGEDGMGGIFPPIVYSYQMMEVLGYAEDHPLRRDCEDAL
EKLLVERPDGSMYCQPCLSPVWDTAWATMALEQARAVPDTRDRPAVSEADLQAGITRAYD
WMAGKQVTELKGDWIENAPADTPAGGWAFQYENPYYPDIDDSAVVAAMLHQRGRAMARLT
GTDPYAEVVTRGLDWIRGLQSRNGGFGAFDADCDRLYLNLIPFADHGALLDPPTEDVSGR
VLLCFGVTGRAEDRPALARAIEYVKRTQREDGSWWGRWGTNYIYGTWSVLAGLALAGEDR
SQPYIARAIDWLRARQNADGGWGETNDSYVDPALAGTNGGESASNFTAWALLAQMAFGDW
QSESVQRGIRYLLSVQQGDGFWWHRSHNAPGFPRIYYLKYHGYTAYFPLWALARYRRLSQ
ARVAASDAPAAAALH
>A0A6P0PVB3|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO4E2|TrEMBL
MQTQDRIVHSGVTKAIANSQSYLLAQQYPDGYWWAELESNVTITAEIILLHKIWGTDKQR
PLHKAEAYLRSQQQKHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDSALVRARDFILR
RGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPEWFPFTIYEMSSWARGSTVPLLI
VFDQKPVFEIEPRINLDELYTEGADQVKFELPRNSDWTDLFVLLDDGFKLAEDWNLVPFR
KQGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPIVQRGLEAIDRFAIE
TPDSYRVQACVSPVWDTAWVLRAMVESGLEPDHPALVRGGEWLLQQQILDYGDWVVKNPQ
GKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLKQAAMARGLAWIASMQCNQGGW
AAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEMLGSCNLSIESQQLENAIAFLIQ
EQEADGSWFGRWGVNYIYGTSSALSALSKIAPHTHQRSIERGAAWLVKCQNLNGGWGETC
LSYDDPTLKGLGISTASQTAWALIGLMAAGEATGNWAMDAIEMGVNYLVSTQQPDGSWDE
TEFTGTGFPSHFYLKYHFYQQYFPLLALGRYQISISS
>A0A4R4SZB7|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. GC306|TrEMBL
MTAVETGTRTRTAAEALAAAQEHLLLLQSPEGWWKGELQTNVTMDAEDLLLREFLGIRTD
ADTAESARWIRSQQAPDGTWATFHDGPPDLSTTVEAYVALRLAGDAPDAAHMARAAAYVR
GAGGVPATRVFTRFWLAMFGRWPWDELPVLPPEMMFLPRWFPLNVYDWACWARQTIVPLA
VAGALRPVRPLPFGLAELEPSDEVPRDRRRGLAGCGLPGWDTAFETLDKALHVYERRPVK
GLRRAALRRAGEWIIARQERDGSWGGIQPPMVYSLIALHLLGYGVEHPVMRRGLEGLERF
TIRDEKGRRIEACQSPVWDTVLAMNALADAGLPAGHPALERAAEWVIGEEVKGPGDWSVR
RPDLPPGGWAFEFDNDCYPDVDDTAEAVIALNRVRHPRAEPAIERGVRWLAGMASRDGGF
GAFDADNTRGLCRRLPFCDFGEVIDPPSADVTAHAVEALAHRGMADSLTAKRAVVWLLKA
QEPDGSWFGRWGANHVYGTGAVVPALIAAGVRPGRPEIRRAVDWLERHQRDDGGWGEDLR
SYRDPAWIGRGVSTPSQTAWALLALLAAGERGEAVERGVRWLAEHQRPDGTWDEDHFTGT
GFPGDFYINYHLYRLVFPLSALGRYLKGS
>A0A7Y9BGM7|squalene-hopene cyclase|EC 5.4.99.17|Bacillus sp. EB106-08-02-XG196|TrEMBL
MINTSKGIDWLVEMLRRDQSPDGSWHYPFETGLSTDAYMIILLRTLEINDEELIKGLAER
ILQRQEKNGAWKLFYDEVTGNLTATVESYYALLYSGYFNKQDKRLRAAKKFILSKGSLDE
VSMFTKVMLSLTGQMKWPSFSPLPIEIILLPLNFPINFYSFSVYGRANLTPLLILTDKKF
TLTTKKSPDLSDLRVGRDDSDTWVRSEEMHSLFSFIEKGVKDLIGLPQQLHKLALQRAKK
YMLDHIEADGTFFSYYSSTFLMIFALLALGNKKNDPVITAAIDGIKAMRTTINGLPHMQY
TTANVWNTSLIGCALQEAGIPPKDTMVLKANQYLLARQHDKFGDWVIHNPNSLPGGWGFS
NINTINPDVDDTTASLRSISRINSSDAWNRGINWLLSMQNDDGGWAAFEKNTDTKLFEFL
PIEKAQFILTDPSCADITGRTLEFFGNYTNLSSDHQSIKKGVKWLLDHQERDGSWYGRWG
ICYIYGTWGAVTGLSEVGVPSSDASIQKAIQWLHRIQNADGGWGESCYSDSKETYKPLGV
STLTHTAWALDTLISVSEQPTSEIRKGISYLLTNLQKEDWTTSYPKGQGMAGAFYIHYHS
YRYIFPLLALAHYRKKFEK
>A0A063BJB9|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. lig30|TrEMBL
QILDVRGDWISRRPNVRPGGWAFQYANPHYPDVDDTAVVVMAMDRADKLTNSSAYRESIA
RAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLTQLGE
TAATSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGADDPRMKRAA
QWLLSIQNKDGGWGEDGDSYKLDYRGYEQAPSTSSQTAWALLGLMAAGEVNHPAVARGIE
YLMTGQQANGLWDEERFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANSTRVTVG
>A0A7W5E710|squalene-hopene cyclase|EC 5.4.99.17|Rhodopirellula rubra|TrEMBL
MPVDNVPQAADFSDQLRRTLDQLRSRLLADRGEDAHWTGELSASALSTATAISALSIACE
QMPSGDRRERYLDLIRRGAEWLKEQQNDDGGFGDTNRSHSNIATSYLVLAAETLARRVDA
FWTPQVNTVLLADSAQPIGTRQSSEPSESSEEVVCERLLRLQRYLEAAGGISALRKRYGK
DKTFVVPILNNLAIAGLVPWSEVSALPFEAAVFPQSMYRYLGMPVVSYAVPALVAIGQAK
FLRSGCLPPWSWVRRASINPTLAVLERMQPDSGGYLEATPLTAFVVMSLVDATATHSLEL
GASPKARSVADERRRRVIESGLQFLEESITPEGSWPIDTNLATWVTSLSVAAMTNDPADQ
REWASEPMVDWILSCQHTRRHPFTGADPGGWGWTDLSGAVPDADDTPGAMVALSNLREHV
TVQQRERIDGAVLDGKEWLLGLQNRDGGWPTFCRGWGKLPFDRSSTDLTAHAIRALKQLP
DCPKSDAAITQGLTFLRKSQRSDGSWVPLWFGNQDRKEEDNPIYGTAKVLVDIHPRFDKN
AVVKGVQYLLKTQNHDGGWGGGESVTRFWAAGNAAKTNANSALLPMPARQTVSSGVENGM
TLQVSDTSGEFTSETATLSSIESRVEGSSGESAVDDSVVSSVEETALAVEALASLWERLN
TTEFAGICDLVPGGPSLTLRTQDAILSGSQWLIRAACAGQLDVAWPIGFYFAKLWYHERL
YPLIFTTAALGRVAGLDDTISRPETTLPR
>A0A3N9VL56|squalene-hopene cyclase|EC 5.4.99.17|Geobacter sp|TrEMBL
MKPCKHPISNALTSFNGMSSEKADTVNLKISAKIHHLPASIWKKKTLENNTPLDVTIQRS
CDFFFREQLPEGYWWAELESNVTISAEYLMLFHFLGMVDKARETKLATYILSKQTSEGYW
SIYYQGPGDLSTTIEAYFALKLAGYPADHPAMEKARAFILKMGGIIKARVFTKIFLALFG
EFAWFGVPSMPIELSLLPNWAYLNMYEFSSWSRATIVPLSIVMATRPVRKLPPWARVQEL
YVRPPRPTDYTFTKEEGILTWKNIFIGVDHLLKIYERSPIRPFMKKAMALSEKWVMDHQE
PSGDWGGIQPAMLNSILALNCLGYSNDHPSIQKGLDALANFCIESEDNIVLQSCISPVWD
TALALKGLIDADVPPDHPALVKATQWLIDREVRKPGDWKIKSPELEPGGWAFEFLNDWYP
DVDDSGIVMMAMKDVKLKDSKAKDDAIERGIRWCLGMQSKNGGWGAFDKDNTKHILNKIP
FADLEALIDPPTADLTGRMLELMGTFGYPKDFPAAERALEFIKATQEPDGPWWGRWGVNY
IYGSWSVLCGLQAIGEDPAQPYIQKTATWLKAKQNTDGGWGETCESYHDKALAGIGESTP
SQTAWALLALMAAGERKSETLTRGVNYLIKTQQQNGTWNEDQFTGTGFPKYFMIKYHIYR
NCFPLMALGKYRSLPGEND
>A0A6B1C9N6|squalene-hopene cyclase|EC 5.4.99.17|Acidobacteriia bacterium|TrEMBL
MKLGAGRDSRAAIAWPPVEDLVIRAEQAVDAACDYLLNRQTSEGYWVGEVEGDTTLESDY
VLLQLWLHQPGSDGTWNPPTRSLVDAACNRIADKQLEDGGWNIYPHGPANINASVKAYCA
LKLGGHSQHSEHLRRAAKRIVDLGGVEAANSYTKLYLSYFDLYRRSDVPSIPPEIFLLPA
EHQFGIYSISSWSRAMLAPLSILGATRARRRVPTGFSLEELFSGRAAPAPALLSWKRFFL
LLDKTIKFLESTEAGRHRERGIEAARDWMIARLERSDGLGAIFPAMVNSIMALTQLGYDS
NHPLLRAQLAHFDDLILHDERGFRVQPCHSPVWDTALTTHAIGAAKARLGDPARWALGRA
ADWLLAKQAREPGDWAVRNPHAAPGGWFFEYRNDHYPDTDDTAEVLLALEYTSAADAQRQ
ARAEERALEWLAAMQSSDGGWAAFDVDSCAAILNHVPFADHNAMLDPSCVDITGRALETL
CRRAPGRYRERVLRGVEYIRRMQHEDGCWYGRWGVNYIYGTCFALRGLRAAGVLPWDSAV
IRAGEWVRSLQNADGGWGESPDSYDDPALRARGASTPSQTAWALMALLATEDYESGSVAD
GVRYLLERQTPQGTWAERAHTGTGFPNVFYLRYHMYPQYFPLMALGEYVRKKGAAQA
>A0A1Y0VA55|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter ascendens|TrEMBL
MNMASRFSLKKILRSGSDTQGTNVNTLIKSGPSDIVRQKSAPQVPADLSALKAMGNSLTH
TLSSACEWLMKQQKPDGHWVGSVGSNASMEAEWCLALWFLGLEDHPLRPRLGKALLEMQR
PDGSWGTYYGAGNGDINATVEAYAALRSLGYAEDDPAVNKAAAWIISKGGLKNVRVFTRY
WLALIGEWPWEKTPNLPPEIIWFPDNFVFSIYNFAQWARATMMPLAILSARRPSRPLRPQ
DRLDALFPEGRANFDYELPTKEGRDVIADFFRLADKGLHWLQSSFLKRAPSREAAIKYVL
EWIIWHQDADGGWGGIQPPWVYGLMALHGEGYQFHHPVMAKALDALNDPGWRHDKGDASW
VQATNSPVWDTMLSLMALHDANAEERFTPEMDKALDWLLSRQVRVKGDWSVKLPNTEPGG
WAFEYANDRYPDTDDTAVALIALASCRNRPEWKAKGVEEAIGRGVRWLVAMQSSCGGWGA
FDKDNNKSILAKIPFCDFGEALDPPSVDVTAHVLEAFGLLGLPRDLPCIQRGLAYIRKEQ
DPTGPWFGRWGVNYLYGTGAVLPALAALGEDMTQPYISKACDWLINYQQENGGWGESCAS
YMEVSSIGRGTTTPSQTAWALMGLIAANRPQDYDAIAKGCRYLIDLQEGDGSWNEEEFTG
TGFPGYGVGQTIKLDDPAIAKRLMQGAELSRAFMLRYDLYRQLFPIIALSRASRLIKIGN
>A0A1N7SD24|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia piptadeniae|TrEMBL
MNDLSMTQTLGDALPQTLIDDHAPVAAALATGAAPVDALDAAVTRATDAILAAQKDDGHW
VYELEADATIPAEYVLLVHYLGETPDVELEQKIARYLRRIQLPNGGWPLFMDGALDVSAS
VKAYFALKMIGDPEDAEHMVRAREAILANGGAEAVNVFTRILLALFGVVTWYAVPMMPVE
IMLLPKWFPFHLSKVSYWARTVIVPLLVLNAKRPVARNPRGVRIDELFRGAPVTTGLLPR
SGHQSKGWFAFFRTVDGVLRMTDGLFPKASRERAIKAAVAFVDERLNGEDGLGAIFPAMA
NSVMMYDVLGYPADHPNRAIARKSIDKLLVIHEDEAYCQPCLSPVWDTSLIAHALLETGD
ERAEEAVLRGLEWLRPLQILDVRGDWISRRPDTRPGGWAFQYNNAHYPDVDDTAVVAMAM
QRAAALTKSDVDGNAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPP
TADVSGRCLSMLAQLGEMPATSEPARRAYDYLLKEQEEDGSWYGRWGMNFIYGTWTALCA
LNAAGISLEDARIKRAAQWLVSIQNPDGGWGEDGTSYKLDYRGYEKATSIPSQTSWALLG
LMAAGYVDHPAVARGIEYLKSEQRDHGLWDEERFSATGFPRVFYLRYHGYRKFFPLWALA
RYRNLTRTGEKRVTVGM
>A0A1W6VSM4|squalene-hopene cyclase|EC 5.4.99.17|Geobacillus thermodenitrificans|TrEMBL
MAGERSALITALKRSQAADGSWRFPFETGISTDAYMIILLRTLDINDEPLIQALVERIES
RQEANGAWKLFADEGDGNVTATVEAYYALLYSGYRQPTDRHMQKAKRRILDMGGLDRVHL
FTKVMLALTGQYPWPGRFPLPLEFFLLPPSFPLNMYDLSVYGRANMIPLLIAADSRYSRK
TDKSPDLSDLFASRGDWGMPESRSLLTYVKRSLIGLPAQLHQAAKQRAVRYLFEHIEPDG
TLYSYFSSTFLFIFALLALGYRNDDPRIRQAVRGLRSLRTTIDGHVHLQYTTASVWNTAL
ASYTLQEAGVPMTDRAIEKANRYLLSRQNVRYGDWAVHNPYSTPGGWGFSDVNTMNPDVD
DTTAALRAIRQAAAKETAFRHAWDRANQWLFSMQNDDGGFAAFEKNVSSRFWRYLPIEGA
EFLLMDPSTADLTGRTLEYFGTFAGLTKDQRAVSRAVDWLLSHQERNGSWYGRWGICYIY
GTWAAITGLTAVGVPAHHPALQKAVRWLLSIQNDDGGWGESCKSDGAKTYVPLGDSTPVH
TAWALDALVAAAERPTLEMKAGFRALFRLLHHPDWTASYPVGQGMAGAFYIHYHSYRYIF
PLLALAHYEQKFGPLDD
>A0A7I8MP38|squalene-hopene cyclase|EC 5.4.99.17|Olavius algarvensis associated proteobacterium Delta 3|TrEMBL
MTAVPSAAPASRDETITAAIDAAIQWLEDHQSREGFWVGILESNVCIEAEWLLAFHFLGI
EEDPKKEGLIRRLVNTQRPDGSWEIYFEATRGDINATVEAYAALRASGMPPDAEPLTRAR
AWILSHGGLRGVRVFTRYWLALIGEWPWKYTPNVPPEIIFFPRWFPFNIYNFASWARATI
LPLSILAARQPVRPLPASARLDELFPGGRHAFDYSLPQKGGPVSWRRFFLLADRFLHAYR
NLGVTPGRELAVKTGLEWIVKHQEADGSWGGIQPPWIYSLMALKVEGYDLDHPVMRQGLG
ALDERWSYERDGGIGIEACQSPVWDTLLTLMALQDCDLDYHHSPAMQHAVEWMFQQQVKA
PDDWQVKVPNARSGGWAFEFANIWYPDVDDTGVALIVLAHLRRVYPDQKRLEEAIELARD
WVIAMQCKNGGWGAFDKDNDTALLTKIPFSDFGETLDPPSVDVTAHVVEAFGLLGMGLSH
PANRRALDYMRAEQETDGSWFGRWGVNHIYGTAAVLPALASVGEDMSAGYVRKAADWIIA
HQNLDGGWGETCASYMNPSLRGKGPSTASQTGWALMALLAVGSDTYRDAIEAGVDYLIAH
QESGTWNEPYYTGTGFPGYGVGARVDLEESDAAGKFQQGTELSRGFMINYNLYRHYFPLM
ALGRARRYLAAAIDRNNES
>K7W6P5|squalene-hopene cyclase|EC 5.4.99.17|Anabaena sp. 90|TrEMBL
MQTQDRIKVKQVVDAIAASQKHLLSIQNPDGYWWAELESNVTITSEAVLLHKIWGTEKTR
PLHKVENYLRSQQREHGGWELFYGDGGDLNTTVEAYMALRLLGVPATDTALLKAKSLILA
KGGISKTRIFTKLHLALIDCYNWRGLPSLPPWVMLLPDNFFFNIYELSSWARSSTVPLLI
VFDRKPIFNIDQPINLDELYAEGVNNVCWELPKNGDWSDIFNILDDGFKLAESINFVPFR
NEGIKAAEKWILERQEVTGDWGGIIPAMLNSLLALKCLDYDANDPVIERGLKAVDNFAIE
TENSYCVQPCVSPVWDTAWVIRALIDSGFAPNDPAIVKAGEWLIEKQILDYGDWNVKNKQ
GKPGAWAFEFENRFYPDVDDSAVVVMALHQAKLRNEELKKQAIDRALNWIATMQCKPGGW
AAFDLDNDQEWLNSVPYGDLKAMIDPNTADVTARVLEMLGACNLSIQPDNLEKSLDYLLK
EQEIEGCWFGRWGVNYIYGTSGVLSALALINPLKYARDINQGAAWLVKVQNSDGGWGETC
FSYNDPNLKGKGDSTASQTAWALIGLIAAGEATDKLAIDSIEKGINYLLETQKLDGTWDE
EYFTGTGFPCHFYLKYHLYQQYFPLMALGRYQAKCSS
>A0A523FAF6|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MTLAQTVEPPSPRDEQPLADLSAVARTVKSVADGLKELQAENGHWAFELEADATIPSEFI
LLDHFLGEIDDEVEAKLAVYIRERQAVHGGWPLFYGGDFNISATVKAYFALKLVGDDPDA
PHMARAREAILAHGGAARCNVFSRFTLALFGEVPWRAVPTMPVEIMLLPSWFPFRLDMVS
YWSRTVIVPLMILSALKPEAKNPRGVGIAELFVTPPHRERRYIVNSTGASLGHVFLLLDR
ILYVGERLIPKRLRAHAIDAAVTFINKRANGEGGLGGIFPAMANTVMAQAALGYPEDDPR
RRASMEAIRKLLVLGPDKGYCQPCISPVWDTGLAMLALMEAGELEDSESMREGVKWLLDR
QILEVEGDWAVRRPGLRPGGWPFQYRNDHYPDIDDTAVVVMALDRARRSGNGVEMRTALA
RAIEWVVGMQSEDGGWGSFDADNTAHYLNHIPFADHGALLDMPTADVTARCVSMLCQLGY
GPGHPAVARGLDSLRRSQESDGSWYGRWGTNYIYGTWSALLALNAAKEDHASPHMRKAVA
WLKACQREDGGWGEDGATYWPERKGEAKASTPSQTAWAILGLMAAGEVESDVVARGVEYL
LSAPRKGPVWSERWHTAVGFPRVFYLRYHGYRTYFPLWALARYLNLMRGATGPGVMGM
>A0A4S2UU64|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. A0592|TrEMBL
MTAPPDPARRSGAPPAHRQPGPPGAGRTAADLPQQPEGSPREVYEATARATRHLLDRQDP
AGWWKGDLETNVTMDAEDLLLRQFLGIRDEATTYAAALFIRGEQREDGTWATFHGGPPEL
SATIEAYVALRLAGDPPDAPHMSRASAWIRANGGIAAARVFTRIWLALFGWWSWDHLPEL
PPELVFLPSWVPLNIYDFGCWARQTIVPLTVVSALRPVRPGPFALDELHTDARTPWPAPR
LAPLASWDGAFQRMDRALHVYRRFAPRRLRKAAMGTAARWIVERQENDGCWGGIQPPAVY
SVIALHLLGYDLGHPVMRAGLESLDRFAVRREDGARMIEACQSPVWDTCLAAIALADAGV
RPDHPALVKAADWMLGEEITRTGDWAVRRPGLAPGGWAFEFHNDTYPDIDDTAEVVLALR
RIRHPDPVRVDAAIARGVSWNLGMQSKDGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSA
DVTAHVVEMLAFEGRAGDARTRRGIAWLLDAQEPDGSWFGRWGTNYIYGTGSVVPALTAV
GIAPGHPAVRRAVRWLESVQNDDGGWGEDQRSYKDRAWAGKGASTPSQTAWALMALLSAG
ERDGKAVERGIAHLVRTQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLYG
EPSVPAGPPAGGP
>A0A6B3EXS1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID11233|TrEMBL
MTATTDGSTGAVDPRAASASRPTTESTIAADDVLAAARRAAERSVEHLLGQQDEQGWWKG
DLATNVTMDAEDLLLRQFLGIQDSTTVQAAGRFIRGEQLGDGTWATFHGGPGDLSATIEA
YVALRLAGDRPEDPHMLRASGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMF
FPKWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPGEPNPPRRPAPAAS
WDGVFQRLDKALHLYHRIAPRRVRRLAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLDHPVMRAGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLRPDHPA
LVKAADWMLDEEIDRPGDWSVRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPD
PARVEAAIARGVRWNVGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHV
VEMLAIEGHSAHPVTRRGIEWLLSEQEAAGGWFGRWGVNYVYGTGSVVPALVAAGLPPAH
PSIRRAADWLESVQNDDGGWGEDLRSYKEDKWIGHGASTASQTAWALLALLAADRRDTAA
VARGVAWLTATQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFAGR
TGLGEGA
>G0Q6I7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. ACT-1|TrEMBL
MTATTDGSTGAANPSEATAHDPTDTTTAADDLTVAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLSIQDPETTRAAALFIRGEQLGDGTWNTFYGGPGDLSATIEAY
VALRLAGDRPDEPHMARAAGWIRDQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPDHPNPPRKLAPPTSW
DGLFQRLDKGLHLYHKVAPRPLRRVAMNLAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMKAGLASLDRFAVRREDGARMIEACQSPVWDTCLATIALADAGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARLQAAIDRGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLASHPRTREGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALITAGLPAGHP
AIRRAVAWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDTRPV
ARGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFADRA
MAAEGA
>A0A5B0DGU2|squalene-hopene cyclase|EC 5.4.99.17|Sporosarcina sp. ANT_H38|TrEMBL
MTYRTEQLISQLVNQLKNDQTPNGSWNYPFESGITTDAYMIILLRSLEINDENLISELTA
RILSKQETNGAWKLFHDEGDGNISATVEAYYSLLYSGYVNKDDFRLLAAKKFVLANGGLE
KSHMLTKIMLAITGQYPWPAYFPLPVEIILLPLHFPINFYDISVYGRANLAPIMILANKK
YVKTSTRSPNLSDLTLSGATDEFLNIQEFQEFFSLIEHDLKSLLGFSQTIHSLAINRTKQ
YMLDHIEPDGTLYSYFSSTFLMIFALLSLGHSNSDPRILVAVKGLKAMQCTIHGHTHMQF
TTATVWNTSLISYALQKAGVPTTDSVINKANEYLLEQQQTKYGDWAIHNPDVLPGGWGFS
AVNTMNPDIDDSTASLRSISQLVQNDHRFHQAWDKGILWIMSMQNRDGGWPAFEKNVYNE
LLNLLPIEGGKFLLSDPSSADLTGRTLEFLGGYTNLPSEHELMKRGINWLVHNQEKDGSW
YGRWGICYIYGTWASITGLMASGVSPENPFVQKSVKWLLGIQNPDGGWGESCKSDLASKY
VPLGSSNLTQTAWALDALIAVSDKATPEINAGISYLQVATNIDNWTISYPVVQGMGGDFY
IHYHSYQYIFPLLALTHYKKKFQG
>G5IYI9|squalene-hopene cyclase|EC 5.4.99.17|Crocosphaera watsonii WH 0003|TrEMBL
MQTQDRLTQKQPLSLKDAITASQNYLLSLQYPQGYWWAELESNITLTAETVLLHKIWGTD
KTRPLHKVEAYLRQQQREHGGWELFYGDGGEISTSVEAYMALRLLGVPQDDPALIRAKDF
IISKGGISKTRIFTKFHLALIGCYDWKGIPSIPPWIMLFPDSFPFTIYEMASWARESTVP
LIIVFNDKPVFSVDPVFNLDELYAEGVENVKYELPKNNNWGDIFLGIDQVFKFAEQVDLV
PFRKEGLKAAEKWILNHQQETGDWGGIMPPMLNSLLAFRTLNYDVNDPSVKLGFEAIDRF
SIEEDDTYRLQACVSPIWDTAWCVRALTDSGLEKDHFSLVKAGKWLLDKQVMEYGDWAVK
NKAGKPGGWAFEFTNRFYPDLDDSATVVMALNGIKLPDEARKQAAINRCLQWIETMQCKE
GGWAAFDLNNDQAWLNEVPYGDLKAMIDPNTADVTARVVEMLGSCDLEIESDRLNKSLNY
LYKEQEKDGSWFGRWGVNYIYGTSGVLSALAVINPEKHKTQMEQGINWLLSCQNKDGGWG
ETCRSYNDPSLKGKGVSTPSQTAWSLIGLLDAGEALNKFETDAIERGVNYLLDTQTEEGT
WEESEFTGTGFPCHFYIRYHFYRHYFPLIALGRYQNLSSEFGVRS
>A0A6B9YMY9|squalene-hopene cyclase|EC 5.4.99.17|Edaphobacter sp. 12200R-103|TrEMBL
MSKISENPQKPDQQKQPRFGRLDLALHQVAEGIRRSKEWLLGQQHPDGYWCGELEADVML
EADYIFMHKLLGTGDPGKLQRALNEILRHQNEDGGWSLYPDGPSNINYGVKAYLALKLMG
WSADHPVLVKAREWVLANGGVVECNTFTKIYLCALGQYDYDAVPAVPPEIVLFPNWSYFN
IYEISSWSRGILVPLSIIYAKKPFKKLPPEQCIDELFVGGRQNADLRLRWDRKNLIGWRN
FFLFTDRMVHWFERVHIRPLRKVAIRRAEKWMLARFEKSDGLGAIYPAMLNSIVALRCLD
YSFDDPQMIRAMDEFEKLGIDCPEGTPDYPTPTFRMQPCFPPVWDTAQAMYALGEAGVSR
TDPQMLKAAEWILSKEIRTKGDWAEKVRNVEPGGWCFEFNNEFYPDIDDTGQVLLALNCV
DYPKERYHYEVCQRALNWVWAMQCKSGGWASFDKDNTKMIFQYIPFADHNAMLDPPTVDI
TGRMLEMLALYGFTRKDPRVEKAVQFILKDQEPDGSWFGRWGVNYLYGTFLVLRGLEAMG
VWNHEPAIQQAAEWIRSVQNADGGWGETCGTYDDPNQRGIGPSTPSQTAWAILGLLAAGD
TRSDSVAKGVRWLIERQHEDGSWDELVPGRNGESYYTGTGFPRVFYLGYHLYKQYFPLLA
LTTYERAMKREAAESAA
>A0A7X4EDK9|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp. SB0673_bin_12|TrEMBL
MDLLINFLGRLSQSFFPPAPHKAQPRHWNPRTPSLKLVSGNRGVAGDVECVQSRTAPATV
GHAEAVEEALSRSARWLLGQQHPEQGYWVQELEADTTLTSEYVMLRRYIGAVDTEQEARM
VRYLQGAQLEDGGWPIYTGAPMDVSASVKAYFALKLAGVPQDDPGMRRARQAILDKGGVV
SANVFTKIALALFGQYDWKGLPSMPPEVVLAPKKFAFNMYAISYWSRAVVIPLLIVFAVR
RECRIPAERGIEELFCTPRDQINYRYAPPFQKDPEFISWRNFFVWIDRILKVYEKYPLRS
VRKKAMKRAEAWLLEHMQGDGGLGAIYPAMANSIFALMALGYPASHPLVQKALREIEALE
IDTPDSAEGPSTLHLQPCHSPIWDTALTINALIERGLPVDHEALSHASSWLRSRQTQKVG
DWVVSSPGATPGGWYFQFENELYPDVDDTAAVLTALAKVSPLQPADRDEVIQRGLKWALA
MQSSNGGWGAYDRDNDQLIFNKIPFADHQSLLDPPTADLTGRCLEMLGALGYDRSHPAVA
PALEFLRREQEADGSWYGRWGVNYLYGTWCVVVGLQAIGEDMSAPWIRRAVAWVESKQNI
DGGWGESCLSYADRAWAGKGESTPSQTAWALLTLLTAGLSDSLSIARGVNFLLRHQLDNG
TWYEPYHVGTGFPRVFYLRYHGYSKYFPMWALAMYRNVRMHGQTRSQALQDVAQSARQRQ
S
>A0A841VW21|squalene-hopene cyclase|EC 5.4.99.17|Nostoc sp. UCD120|TrEMBL
MQTQDRVKVNLAEAIAASQEYLLSIQNPAGYWWAELESNVTITAEAVLLHKIWGTDETRP
LHKVEAYLRQEQRQHGGWELFYGDGGELSTSVEAYMALRLLGVPASDPAMIRAQAFILQR
GGISKTRIFTKLHLALIGCYNWRGIPSLPPWIMLLPKAFPVNLYEMSSWARSSTVPLLIV
CDRKPVFITNPTINLDELYAEGIDQVRWELPQAGDWTDLFLTLDQGFKWAESLNLVPFRE
EGIKAAEKWILERQEATGDWGGIIPAMLNSMLALRCLDYDRSDPIVERGLQAIDNFAIET
ENSYRVQPCISPVWDTAWAMRALVESGFAPDHPAVVKAGEWLLQKQILDYGDWAVKNRQG
KPGAWAFEFDNRFYPDVDDSAVVVMALHLAKLPNEKIKQAAIARAVNWIASMQCKPGGWA
AFDLDNDQDWLNSIPYGDLKAMIDPNTADVTARVVEMLGACDLSIDSDNLERSLTYLLHE
QESEGCWFGRWGVNYIYGTSGVLSALALIDPQRHKLSIERGAAWLVGCQNPDGGWGETCR
SYDDPSLKGKGNSTASQTAWALIGLLAAGEATGKLALEAIEQGIGYLVATQKSDGTWFEA
DFTGTGFPCHFYLKYHLYQQYFPLIALGRYQAVMGSTNLSLS
>A0A7V5CLJ6|squalene-hopene cyclase|EC 5.4.99.17|Armatimonadetes bacterium|TrEMBL
MKSRVSANQNRQAADESVEQNNLESALSGALRYLLNIQYEEGYWSAELEGDTILESEYII
LMRFLGRGDEARLKKAANYLLSKQMSNGGWAIYPGGPVDVGASVKSYFALKLTGSSPDKP
YMIKAREAIWQAGGVPASNSYTKFYLAMLGQIPWNDAPAVPTELMLLPKWFYLNIYEISS
WSRTFVVPLGIIWAHKLTTPIPHEQGISELFRKDERRHVRLKMRGIAPSWRNFFIGIDAL
VKLAEQWKILPWRKKAVSKAEQWMLEHMEHSAGLGAIFPPMVYALVALRALGYSDDSPEV
KRAWDELEALGIEDSNTLRLQPCTSPVWDTAIAINALAEAGIAPDDPAMTKATRWILDKE
VRIKGDWRIKRPDLEPGGWYFEFENQYYPDIDDTAMVLMGLAKTADIPGKSEACERGLNW
LMGMQGRDGGWASFDVDNNKSIFNYIPFADHNAMLDPSTSDITARILEMFSFCGIDSGRR
EVLRAIDFIRKEQEADGSWYGRWGVNYIYGTWQVIRGLTRIGINPSDSMIRKGAQWIMSV
QNEDGGWGESCDSYVDPNLKAKAPSTASQTAWAVMGLMCAGETGSNAVKRGIDYLIRTQN
ESGTWDEEWFTGTGFPKVFYLRYHLYRHSFPLMALGMYRRLIEEKEPEQSI
>A0A3Q9C4R9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces aquilus|TrEMBL
MTATTDGSTGALPPRAAAASDTDINTPVAAGVREAAASAVRRATDHLLARQDAEGWWKGD
LETNVTMDAEDLLLRQFLGIRDESTTRAAGLFIRGEQREDGTWASFYGGPGELSTTIEAY
VALRLAGDAPDAPHMAKAAAWIREQGGIASARVFTRIWLALFGWWKWEDLPELPPELIYF
PKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAHPNPAKPLAPVASW
DGAFQRLDKALHQLRKVAPRRLRKAAMNSAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLEHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALVDAGVAPDHPQL
VKAADWMLGEEIVRPGDWSVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHDP
DRVENAIGRGVRWNLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIEWLLAEQEPNGSWFGRWGVNYIYGTGSVVPALVAAGIPAAHP
AIRRAVTWLETVQNDDGGWGEDLRSYKDSKEWSGRGASTASQTAWALMALLAAGEKDSKA
VERGVEWLAATQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFSQA
GEA
>A0A7L9CCT9|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetia bacterium|TrEMBL
MRNFLLNLFERLETSIYKFNGNGNGNGKHPVPELSKDNLLFESLPIQTGFHALSAVKNPL
EIGIHRSQQYLLKSQNPLDGHWVGILEADTTITAEYIMVMHFLGKIDHKKQKMAANLLRD
HQLSDGGWNIYYGGPSEISASVKAYFALKLAGYTADEPFMQRARKCILEKGGIMKANCFT
KIYLAMFGQVDWQAVPAVPAEMILFPPGFFFSIYEMSYWSRCIVVPLSIAIAKKPHIPVG
DDLLKEIYLIPREKVVYRIKRDQPSLSWRNFFIDADSIFRRYERQPIQCIRRIALRKAEK
WMLDHLEKSGGLGAIWPAIVNSIFAMKCLGYPDDHPALVKQIQEMENLIVYDGDSLYLQP
CVSPVWDTAWAVIALHESGISSADPVLQRAGQWLLSKEIRNFGDWSLKCKVDEPSGWYFQ
YANEFYPDTDDSAAVLMALQRISLPETAHKEAAFLRGIRWLLAMQCDDGGWGAFDRNNNK
TILNHIPFADFNALLDPSTSDVTARCLDFLGRTGFGKSSQHVRKAIEFLKKEQEKDGSWF
GRWGANYIYGTWSVLSGLSAAGENMNASYIRRAIDWLKNVQNSDGGWGETIQSYDDPFLK
AIGKSTPSQTAWALLGLIVGGEIKSDAVEKGIKFLLAKQKEDGSWDESEFTATGFPKVFY
LKYHMYRNYFPLTALSRYRNLIQNFKGK
>A0A7S7UTN5|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. CCBAU 53338|TrEMBL
MDSVNPTSGEALESSIASATQGVLGFQQPDGHWVFELEADCTIPAEYILLRHYLAEPVDV
ALEAKIGNYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDSVAAPHMVRAREAIH
ARGGAINSNVFTRFLLATFGVVTWRAVPVLPIEIVLLPFWSPFHLNKISYWARTTMVPLM
VIAALKPRARNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFVLFRALDGILRVVEPMFP
RRLRKRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKDETFPPRAITRRGIDK
LLVIKGDEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAARQGLDWLIPRQELEVKGDWA
VKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGATGYDAAIDRGREWIEGMQ
SDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETEKTSKHVAD
GVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDRNDPMMRKAADWLASIQNKD
GGWGEDAVSYRLDYRGWEAAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIATQNEKG
LWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A7H8LPG1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces seoulensis|TrEMBL
MTATTDGSTGATLPTRAAAASEPVLTTPVAAGVHQAAEHAARRATDFLLSKQDAEGWWKG
DLETNVTMDAEDLLLRQFLGIQDEATTRAAALFIRGEQREDGTWATFYGGPGDLSATIEA
YVALRLAGDAPDAPHMAKAAAWVRARGGIAAARVFTRIWLALFGWWKWEDLPELPPELIY
FPTWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPARPNPVKPTARAAS
WDGAFQRLDKALHAFRKVAPRRLRRSAMNTAARWIIERQENDGCWGGIQPPAVYSIIALH
LMGYDLQHPVMRAGLKSLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQ
LVKAADWMLGEEIVRPGDWSVRRPGLPPGGWAFEFHNDNYPDIDDTAEVALALRRVRHHD
PERLDKAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGLAHDPRTRRGIQWLLAEQEPDGSWFGRWGVNYIYGTGSVVPALTAAGLPASH
PAIRRAVAWLERVQNDDGGWGEDLRSYRDTKKWSGKGASTASQTAWALMALLAAGEKDSE
AVERGVRWLADTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFAA
EAPAGRPLAEAKGS
>A0A3P0SNK3|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp9004|TrEMBL
MNDLTDMANLSAGTVPAGLDAAVASATDALLAAQNADGHWVYELEADSTIPAEYILLVHY
LGETPNLELEQKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPIAKNPRGVRIDELFIDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKSIEKLLVVHEDEAYCQPCLSPVWDTSLVAHALLETGDARAEEAVLRGLDWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLKQTDTYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTSDVSGRCLSMLSQLGESAL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRVKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLI
AQQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A7K3CF24|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4912|TrEMBL
MTATTDGSTGAANLRAVTFGDPIEPTTDTDDVLAAARRAAGRSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETVQAAARFIRGEQLGDGTWNTFHGGPPDISATVEAY
VALRLAGDLPDDPHMLRAAGWVREQGGIAASRVFTRIWLALFGWWKWEDLPELPPELMFF
PSWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPEHPAPPRPLAPAASW
DGVFQRLDKALHAYHKVAPRRLRRIAMNAAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLEHPVMRAGIASLDRFTVWREDGSRMVEACQSPVWDTCLATIALADAGVPPDHPAL
VRAADWMLGEEIVRPGDWSVRRPQLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDQ
PLVDAAIERGVRWNLGMQSRDGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLATDPRTRRGIQWLLDEQEASGAWFGRWGVNYIYGTGSVVPALIAAGLPASHS
SVRRAVSWLESVQNDDGGWGEDLRSYREEKWIGHGASTASQTAWALLALLAAGERESGVV
ERGVTWLAETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFATAG
TGTAAGREA
>A0A367FJQ6|squalene-hopene cyclase|EC 5.4.99.17|Sphaerisporangium album|TrEMBL
MTTYLTTVDVHLPDSSAGLALGAACDHLIRLRSPQGWWKGELQTNVTMDAEDLLLREFLG
IRTEHDTAEAARWIRSEQRADGTWANFHGGPGDLSTTVEAYVALRLAGDPVDAAHMRAAA
AYVLRSGGIEATRVFTRIWLALFGGWRWEDLPVMPPELMYLPSWAPLNVYDWACWARQTI
VPLTIVSAHRPVRPLPFGLDELRTGRPVPRRRGLGWDGVFGGLDRLLHRYQRRPVRGLRE
AALRRAAEWIVARQELDGSWGGIQPPWVYSLIALHLSGYHLDHPVMRRGLEGLDRFTIRD
GRGRRLEACQSPVWDTALAVNALLDAGVPADDAVIARAADWLVGEEVKGPGDWAVRRPHL
PPGGWAFEFHNDGYPDTDDTAEVVLALRRTRRPGARQAIDRAVRWMEGMASRDGGFAAFD
ADNTRTLCTRLPFCDFGAVIDPPSADVTAHVVEALAHERPAGSETLRRAVIWLLKAQEPD
GSWFGRWGANHVYGTGAVVPALVAAGVRPESTCVRRAVAWLRAHQNDDGGWGEDLRSYTD
PAWIGRGESTASQTAWGLLALLAAGERSDEVDRGVRWLVDHQRPDGTWDEPYFTGTGFPG
DFYINYHLYRLIFPISALGRYLHAREADAAAGFRARGTPPVHDGAGTRRAPGGDATAKAG
TRDGIWKLREGDKSGGLRDGSCGVGDGSGGVRDGSGRVRDGSGGVRDRSGGVHDGPGGVR
DGGTAGTAAS
>A0A372ZLC0|squalene-hopene cyclase|EC 5.4.99.17|Kitasatospora xanthocidica|TrEMBL
MGDRPPALLGTGRWQPEDTDQPRPAGETDHGPADAREALARATTHLLSLQSSEGWWKGDL
ETNVTMDAEDLLLRQFLGIRTEEQTRATAEWIRSQQREDGTWSTFHGGPPELSTTVEAYV
ALKLAGDDPEAPHMLAAARYVRSAGGIAAARVFTRIWLALFGWWPWERLPEMPPEIIFLP
RWLPLNIYAFGCWARQTIVPLTVVSSHRPVRPAPFPLTELHTDPNDPYPHRPLAPATTWD
GLFERLDKALHAYHRRAFRPLRRLALSQACRWIVERQEADGCWGGIQPPAVYSLIALHLE
GYELEHPVMKAGLSSFDRFTVHTEDGKRWLEACQSPVWDTCLATIALVDAGVPADHPALV
SAVDWMLGEEIRKPGDWTVKRPGLAPGGWAFEFENDTYPDIDDTAEVVLALRRVAHPDPA
KVDGAVDRGVLWNLGMQSKNGAWGAFDVDNTSTLPNKLPFCDFGEVVDPPSADVTAHVVE
MLAETGRSRDPRTRRGIEWLLRNQEADGSWFGRWGTNYIYGTGSVLPALVAAGVPDEHPA
IRRAVRWLEDRQNADGGWGEDMRSYDDPARWAGRGDSTASQTAWALMALLAAGEGPKDRA
NPAVERGAEWLVRTQLPEGTWDEPQFTGTGFPWDFSINYHLYRLVFPVTALGRYLNGAPG
TIRADGTPAIGTAR
>A0A3L7NJ51|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MDSIMSHIGHNEIGVQESASRDAGRSSCMPERSRSVSPTFESKAIDSAHRTCQWLSDRQA
QDGHWRGALQGDTILESEYLLILAWAGKLHGPKVLGATARILKEQLPAGGWAIHPGGPPD
VSASVKAYFALKLTGHDPHCDAMRSARTAIAACGGVPAVNSFTRFYLALLGQIPYSACPA
VPPEMVLLPDWFPINLHCVSAWSRTMIVPLSLIWAFKPLRMVPADFGIGDLFSGDDQRRA
SVPGGQARGWGTFFRVVDRCIKACDWIGLRPLRARAIAECRRWMLERFEGSDGLGAIFPP
IVWSIVALRAMGCADESPEVQECWNQLNELVEVEKDGCTRVEPCRSPVWDTAISLRAMSD
AMSAGISIGFADLERAVEWLLDREIRTVGDWSHRTKAEPSGWCFEYSNRFYPDVDDTAMV
LIGLAAWRRAAIVSLTGQLIDLELLQRVEKAMQRGKHWLKAMQNSDGGWGAFDRDNNMEL
LCKVPFADHNAMIDPSSPDLAGRVLEAFGAIGMRSCDGDPSIDRAIKYLRTTQEANGCWY
GRWGVNYIYGTWQSIEGLRSVGVSVEDSAIVRGADWLASCQQDAGGWGESPLSYADPTWA
GCGDLTASQTAWALSGLLSAGRIDSPEVRRGVRWLLSEQLQDGSWEEQAFTGTGFPKVFY
LRYHYYPIYFPLISIVKWSCEMEKERVGHSRLGYVA
>A0A7Y3XCP3|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MRNFLISFFERLETSIHKFNGNGNGNGNGNHPIPELSEHELRFESMPLGAGFHTPLSTKN
PLDITIYRAQQYLLRNQNRSDGHWVGILEADTTITSEYIMLMHFLGKVNQEKQRLAANLL
CEHQISDGGWNIYYGGPSEISASVKAYFALKLAGYSANEPFMQKARKRILEMGGIMKANC
FTKIYLAMFGQVDWQAVPAVPAEMILFPPGFYFSIYEMSYWSRCIVVPLSIAIAKKPHIP
VGDDMLKELYLIPREKVVYRIKRDQSGLSWHNFFIDADSIFRRYEQQPIKFIRRMALRKA
EKWMLDHVEKSGGLGAIWPAMVNSIFAMKCLGYPDDHPALKSQLQEVENLVVYEVNKLYL
QPCVSPVWDTAWAIIALHDSGIPGSDPALQKAGRWLISKEVRNFGDWALKCKVEEPSGWY
FQYANEFYPDTDDSAAVLMALQRVSLPETAHKEASVLRGLRWIMAMQCDDGGWGAFDRNN
NRAILNHIPFADFNALLDPSTSDVTARCTEFLGRIGFSKTSGQIRMAIEFLKKEQEKDGT
WFGRWGANYIYGTWSVLAGLAAVGEDMNKPYIKKAVAWLKSVQNSDGGWGETIKSYDDPF
LKAIGKSTPSQTAWALLGLMAAGEIHSDAVERGIKFLLMKQKEDGSWDEVEFTATGFPKV
FYLKYHMYRNYFPLMALGRYRNSIHNKV
>A0A7W6S153|squalene-hopene cyclase|EC 5.4.99.17|Roseospira goensis|TrEMBL
MNQTLHKTPVIDFDTQTPFDALIAHGPDVAGDPARTGAGGDPAGAGATTPDSSALDAAIG
EAAGWLQTRQRDDGHWIFELEADATIPAEYVLLNHFLDQIDAPLERKIAVYLRGMQGAHG
GWPLFHDGDFDMSASVKAYYALKLVGDHPDEPHMARAREAILKRGGAARTNVFTRFTLAM
FGQVPWRACPVSRVEAMLLPRWFPFHLDKVSYWARTVMVPLFVLYSRRARAVNPRGVGIR
ELFVTPPERERRYHRNPTGHWIGTAFLGLDKVVRVLEPLFPRAVERRATETALRFVEERL
NGEDGLGGIFPAIANCLMVYHILGYPKDHPNVRIARRAIDGLVVDKGSHAYVQPCLSPVW
DTGLASMALCETNAQGGDDRAVSATRETAVTNACHWLRDRQILDTVGDYAAMRPGVRPGG
WAFQYNNDHYPDVDDTAVVSMLLHRTGDPANKESVERAAEWIIGLQSKNGGWGAFDADNE
YYTLNNIPFADHGAMLDPPTVDVSARCIGFLSQIGYERDHPVVARGLAFLRAQQEPDGSW
FGRWGTNYIYGTWSALSAFNAVGEDPQAPHVRAAVAWLHRRQQADGGWGEGCESYWSDKR
DFVKASTPTQTAWALLGLMAAGEVDSEPVRRGVDYLLKAPREGGRWTEDLYNAVGFPRVF
YLKYHGYPVFFPLWALSRYRNLTRGNSKHVSWGL
>A0A2Z4UZ14|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. ICC1|TrEMBL
MTTEATEAIALTASVDRSLALAARTLRERQDPAGHWKGDFETSLIGESGEVILRHFLRLP
DDGTAAAAASTILSEQTATGGWASYYQGPDELLLSIFCYVALRLAGHDPDEPEMRAAAGS
IRAGGGIEGVDNLLMLAWLALIGLWPWRDIPLIPAEIVLLPSRFPGNIYQFGAAARGIVV
ANSLFMADRPVVPAGFDIAELFAKPSARRRLPRPAALRIGTTLTHWYARHPIGFLRRRAV
RKAADWLVRTQETDGSWGGNWPQTANVVMGLDAVGFGQDHPVVKAAMEGLDRYVVEKDGH
RRVEMWTSVVMDTALGLHATAAAGGPDTKSAAEPAVRWLLANQVTELGDWAVLTKDPVAG
GWPYEFTNNANPDADDTAFAVAALRRFHPRGSDAAVDEACERAGRWMESQQCDDGGWAAF
EPLRWKLPGRDKLAAIGFLEAPSADVTGHVLEALGSDGQARTPAALRGIEWLRENQHADG
SWPGWWACYHLHGTSAAVTGLTACGIPGTDPAVARACEWIVAHQQDDGGWGEDIRALHDP
AWIGNGASTPSQTGWALLALIAAGRADSEEVRAGLEFLVRTQQEDGDWAEPWHTWVVHHD
GLYWRDSLLRLIYPVMAMSAYLARTDGSEER
>A0A7W4P128|squalene-hopene cyclase|EC 5.4.99.17|Gluconacetobacter asukensis|TrEMBL
MMVNATDTLERPSADVADLAVPMIEIDQAVDAGHAALGRRQNDDGHWVFELEADATIPAE
YVLLEHYLDRIEPALEARIGVYLRRIQGDHGGWPLYHGGRFDLSASVKAYFALKAIGDDI
NAPHMARARAAILDHGGAERSNVFTRFQLALFGEVPWHATPAMPVELMLLPRKAFFSVWN
MSYWSRTVIAPLLVLAALRPRAINPRDVHVPELFVTPPAQVRDWIRGPYRSPLGRVFKYV
DKVIRPGERLIPEATRRRAIKAAVDFIEPRLNGVDGLGAIYPAMANSVMMYRALGVPDSD
PRAATAWESVRRLLVEHGDEAYCQPCVSPIWDTGLAGHAMIEAASGPEGIRPEETKKKLA
AAAQWLLDRQILNVKGDWAINCPDVAPGGWAFQYNNDYYPDVDDTAVVGMLLHREGDPAH
HEAIERARQWIIGMQSTNGGWGAFDIDNNMEFLNHIPFADHGALLDPPTADVTARCVSFL
AQLGRPEDRPVIERGIAYLRTDQEAEGCWFGRWGTNYIYGTWSVLCALNVAGMSHDDPAI
VRAVDWLRSVQREDGGWGEDCATYEGATAGIYTESLPSQTAWATLGLMAAGLRDDPAVAR
GMAYLARTQKEDGEWDEDPYNAVGFPKVFYLRYHGYRQFFPLMALARYRNLESSNTRRVA
FGF
>A0A7C3EDB0|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MNAVPVSSVRPGASAPGDTWSARIDEAIRRSQEFWLGQQKPEGYWIGELIVDVTLVADMV
AFHHWDRSVDPAWQRKAVRHIFDKQLPDGGWNIYHGGPAEVNATIKAYLALKLAGVSPTH
PRMLRAREVARSLGGVPRLNTFSKLYLALLGLYPWKYVPTIPCEVLLLGKWFRVNFWDMS
NWTRAMLVPLAIINHFRPTRPCGVDLDELYPEGFHERDLRLPRDPDWFTWRNFFLCLDKL
HKFAELWARAGIHPFRRRALRKAEQWMLERFEGSDGLGAIFPAMLNSLIALKALGYPDDH
PEVIRARQKLKELEHETADSIRIEPCFSPVWDTAIVTIALRESGLPADHPAVVRAANWLL
DREIRFRGDWQYKNPAPVEPSGWAFEFNNKWNPDVDDTAMVLLALRLVPTEDPARRDAAF
RRGLNWMLTFQCRDGGWAAFDKDCTNNILEKVPFADHNAMLDPECADITARILELLGREG
FPLDHPQVRRAIAYLRSQQEADGSWYGRWGVNYIYGTWQVLRGLHALGMDMHQPWLLRAR
DWLESVQHEDGGWGERCNTYDDPVFKGQGPSTASQTAWAVMGLCAFGDPHRPSLRAGVEY
LLRTQNPDGTWTEEETTGTGFPKVFYLKYDSYRNAWPLLALATYRQLCQRARGT
>A0A6B1A846|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MTTAAGSPITDDALSRTIEGATNWLLEQQDPAGFWWGELESNPSITAEYLLLTHHLGIGD
RQQWDGIARYIRAQQRPEGFWAQYLNGPGDVSTSVEAYFALKLAGDDPDSPHMTRAREWI
LEQGGIVRARVFTKIWLAMFGEFDWDRLPAMPPWINLLPSWLPINLYEFASWARATIVGI
TVIMTLRPTAALPAGAGVPELWVRPSDRRRFAVPPPRNPFSAAGAFYVVDSLLRFLDRNR
IRPFEHRALAFSERWLLDRQEADGCWGGIQPPWVYAILALRAMGYSLDHPVMRRALAGFE
RFTWKQSDRGGEQIWTESCQSPVWDTCLAAVGLLDAGLDPQHPALQNAARWMLREQVLSG
GDWQVKNPDTPPGGWAFEFDNDVYPDVDDTAVVLMALERIPMPGLESERQLALDRGLHWM
LSMQSSGGGWGAFDVDNEKTFLAEMPFADFGELLDPPTADVTAHALEYIGQLGYSGQYPP
ASRGLRFLYDVQEPDGSWWGRWGVNYIYGLGAALPALQALGEPMSAPAVRNAVEWLFRHQ
LEDGGWGESCDTYADPSLRGLGPSTPSQTAWALMALIAAGEAEHESVVQGVRYLVERQRE
DGTWDEPEFTGTGFPSDFMINYHLYRHYFPLMALGRYERAVAAR
>A0A0E1TQ67|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia pseudomallei 576|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGAVDNPAVARGVDYLL
GTQREHSLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A536H888|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
PVKSLGCSVPELVVPGTEDLLTRVPGSGLFWWTDKLLKLNEAFPWQPGRSRARRRVVDWI
VERQEADGSWGGIQPPWVYSLIALYLEGMSTDHPVMRRGIEGQEGFVLEDESGWRFQACM
SPVWDTAWALLALRHAGVERDHPGIQRAVQWILQEQISVGGDWQVRGGTVPCGGWAFEFE
NDIYPDIDDTAVVVLALLEAGAEAAVRTAVDRAARWVLAMQSSNGAWGAFDKDNTRAIVY
RLPFADFGALLDPPSEDVTAHVLEMLAHVDAPDKERVIRVALKYLRHTQRPDGSWFGRWG
VNYIYGTWCVISALAALRDEGYAVQDMIDRGSSWLLEHQNSDGGWGESCYSYEDSSFAGI
GQSTPSQTAWAILALQLVGLGQHAACLRGLTYLCETQVDDTWEEREYTGTGFPRDFYINY
HLYRHLFPTMALAGACKAKVDMAFPFCLP
>A0A0M0EKA1|squalene-hopene cyclase|EC 5.4.99.17|Komagataeibacter europaeus|TrEMBL
MMAKRTETATVTRPRRTTPSTRKAATPKAALDAPLDQAELDQAVTRAHAALGGRQADDGH
WVFDLEADATIPAEYVLLEHYLNRIDPDLEQRIGIYLRRIQGDHGGWPLYQDGTFDLSAS
VKAYFALKAIGDSVHAPHMVRARHAILDYGGAERTNVFTRIQLALFGDVPWEAAPVMPVE
IMLLPRRALFSVWNMSYWSRTVIAPLLVLAALRPAAVNPRRVHVHELFVTSPGKVRDWIR
GPYRSVWGHVFRYADAMLRPAERLIPEKTRRRAIKAAVDFIEPRLNGLDGLGAIYPAMAN
TVMMFRALGISDEDPRAKAAWEAVRRLLVNQGKETYCQPCVSPVWDTGLAGHAMIEAASG
PDGIAPEETKQKLAAAGRWLRERQILNVRGDWAVNRPDVRPGGWAFQYANDYYPDVDDTA
VVGMLLHRDGDPANADAVARAREWIIGMQGSNGGWGAFDVDNSRDVLNHIPFADHGALLD
PPTADVTARCISFLAQLRQVEDHATIERGIAYLRREQETDGSWFGRWGTNYIYGTWSVLC
ALNAAGMPHDDPMIIRAVDWLRHHQRADGGWGEGCESYEGGMHGDYKQSLPSQTAWAVLG
LMAAGLRDDPAVARGIAWLGRTQGKNGEWKEEPYNAVGFPRVFYLRYHGYRQFFPLLALS
RYRNMQIGNTGRVGYGF
>A0A346A190|squalene-hopene cyclase|EC 5.4.99.17|Pseudolabrys taiwanensis|TrEMBL
MMNGDLEARVASGRVDEALNRAITTACDTLFAQQQPDGHWLYELEADATIPAEYILLRAY
RGEPDAPELERKIGNYLRRIQGAHGGWPLFQDGDFDMSASVKAYFALKMIGDAPDAPHMK
RAREAILTRGGAIHSNVFTRILLSLFGVLRWQSVPTMPVEIVLLPSWFPFHFSKVSYWAR
TVMVPLLVLQTLQPRAKNPRGIGIDELFLQPPHSIGLAAKAPHQNWGWFTFFRAVDIVIR
PLSALSPRALRQRALKAADDFVTERLNGKDGLGAIFPAMANAVMMFDLLGGPENEKKAAI
ARDSVERLLVINDDEAYCQPCLSPVWDSALAAQALLEEGSPKSVESARKALDWLVPLQVL
DVKGDWIARRPDLRPGGWAFQYANPHYPDLDDTAVILMAMDRARQEGVGDRYDPAIARGV
EWIKGMQSSNGGWAAFDVDNTFSYLNNIPFADHGALLDPPTEDVGARCVSMLAQIGEKDS
DAVKRGVDYLRSQQLPDGSWYGRWGLNYIYGTWSVLCALNAAGIPATDPAMRKAAQWLLS
IQNADGGWGEDGTSYKLEYQGHEPAPSTASQTAWALLGLMACGEASHAAVAKGVAYLART
QNDEGLWDEERYTGTGFPRVFYLRYHGYRKYFPLWAMARYRNIMSGANQPVRYGM
>A0A4Z0E3M2|squalene-hopene cyclase|EC 5.4.99.17|Methylorubrum sp. Q1|TrEMBL
MREAAVSKVETLQRPKTRDVSLDDVERGVQSATRALTEMTQADGHICFELEADATIPSEY
ILFHQFRGTEPRPGLEAKIGNYLRRTQSKAHGGWALVHDGPFDMSASVKAYFALKMIGDD
IEAPHMRAVRKAILQRGGAANANVFTRILLALYGEVPWAAVPVMPVEVMHLPKWFPFHLD
KVSYWARCTMVPLFVIQAKKPRAKNPRGVGVAELFVTPPDSVRTWPGSPHATWPWTPIFG
GIDRVLQKTQDHFPKVPRQRAIDKAVAWVSERLNGEDGLGAIFPAMVNSVLMYEVLGYPP
EHPQVKIALEAIEKLVAEKEDEAYVQPCLSPVWDTALNSHAMLEAGGHQAEANARAGLDW
LKPLQILDIKGDWAETKPNVRPGGWAFQYANPHYPDLDDTAVVVMAMDRAQRQHGLVSGM
PDYSESIARAREWVEGLQSADGGWAAFDADNNHHYLNHIPFSDHGALLDPPTADVTARVV
SMLSQLGETRATSRALDRGVTYLLNDQEKDGSWYGRWGMNFIYGTWSVLCALNAAGVDPQ
SPEIRKAVAWLIRIQNPDGGWGEDASSYKLNPEFEPGYSTASQTAWALLALMAAGEVDDP
AVARGVNYLVRTQGTDGLWSEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKRGNS
RQVQFGM
>A0A850PA68|squalene-hopene cyclase|EC 5.4.99.17|Ameyamaea chiangmaiensis|TrEMBL
MLNDIDAPLRPDPAPADTITPDALERAVSNAHAALSNRQNDDGHWVFELEADATIPAEYV
LLEHFLDRIDPELESRIGVYLRRIQGDHGGWPLYHGGGFDLSASVKAYFALKAIGDDIDA
PHMRRAREAILDHGGAARSNVFTRFQLALFGEVPWRATPVMPVELMLLPRKAFFSVWNMS
YWSRAVIAPLLVLAARRPRAINPRGIHVQELFTVPPETVRDWIRGPYRSVWGRAFKYLDV
ALRPVVPRLPRTLHERAIQAAIDFIEPRLNGRDGLGAIYPAIANTVMMYRTLGVPDSDPR
AATAWQAVQGLLVHNGAETYCQPCVSPIWDTGLTGHAMLEASDGPSGIRPEETRERMARA
ADWLRTKQILDVKGDWAVNAPDLEPGGWAFQYGNDYYPDVDDTAVVGMMLHREGNPDSAE
AIDRARRWIIGMQSTNGGWGAFDIDNDLDLLNHIPFSDHGALLDPPTADVTARCISFLAQ
LGHPEDRPVIERGIDYLRREQEAEGSWFGRWGTNYIYGTWSVLCAYNAAGVAHDDPSVRR
AVAWLRSVQREDGGWGEDCATYEGAASGEYDESLPSQTAWAVLGMMAVGLRDDPAVRRGV
AFLMNAQDERGEWHEEPYNAVGFPKVFYLRYHGYKQFFPLMALSRFRNLGSSNSRQVSYG
F
>E8WLT7|squalene-hopene cyclase|EC 5.4.99.17|Geobacter sp. (strain M18)|TrEMBL
MTSPFKHPISHALTSFNGIVTEPEQSVEQKAGAKVHQFPASLWKSKPGKAKSPLDIAIEG
CRDFFFREQLPKGYWWAELESNVTITAEYIMLFNFLSLVDHERQRKMSNYLLSKQTEEGF
WTIYYGGPGDLSTTVEAYFALKLTGYPADHPAMVKARAFILEKGGVIKSRVFTKIFLALF
GEFDWLGVPSMPVELNLLPNWAYVNVYEFSSWARATIIPLSIVMLKRPVHKLPPSQRVQE
LFVRPPRAIDYTFTKEDGIFTWKNFFIGLDHMLKVYERSPVRPFKKRAMGKAEEWVLEHQ
EETGDWGGIQPAMLNAVLALSALGYDNGHPAVAHGLKALENFCIESDEQIVLQSCISPVW
DTALALKALVDAGVPSDHPSLVKGAQWLLEREVRRPGDWRVKSPDLEPGGWAFEFLNDWY
PDVDDSGFVMIALKGVEVKDRKAMNAAVKRGIDWCLGMQSKNGGWGAFDKDNTRHILNKI
PFADLEALIDPPTADLTGRMLELMGTFGYAKTYPAAQRALKFLKENQEPEGPWWGRWGVN
YLYGTWSVLCGLAAIGEDLEQPYIKKAVNWIKSRQNMDGGWGETCESYHDPTLAGMGEST
ASQTGWALLGLMAAGEVHSATVVRGVQYLISTQSQDGTWDETQYTGTGFPKYFMIKYHIY
RNCFPLMALGTYRTLTGGTA
>A0A5B0WXB5|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus sp. B2(2019)|TrEMBL
MNPILSTVDNEIERLTAFLIDQQQQDGSWHFCFENGIVIDAYVIILFRILNVQNEALIRQ
LHDRILAEQQSAGFWQLYRDEEDGNLSTSVEAYYALLYSGYSKVTDEPILRAKHYIQSKG
GIGKVTSILTRVILAATGQSKWPLSISSIPLEVLLFPSYFPINYFEFSGYSRVHLTPMLI
MADRRFSISTVNAPDLSDLIDTRIEDAEPASRGYQELQDVIQTGLSRLLGSPRYIHEVAR
TKAEQFILQRIESDGTLYSYATSTILMVYALLALDYDQQHPLIMNAIDGLTSMQCRSESK
TTIQNSPSTIWDTALIAYTLQEAQIPDHHLAIQRATSYLLTRQQHKTADWSIHNPDTTPG
GWGFSESNTINPDVDDTTAALRAIRSLSITQPSYLESWNRGLNWVLSMQNKDGGWPAFEK
NTNKEMLTWLAIDGAKSAAIDPSEADLTGRTLEYLGNFADLDARNEFIGRGVKWLIQHQE
KDGSWYGRWGVCYIYGTWAAITGLQAVGLPLEHETLQKGANWLLSIQNSDGGWGESCHSD
RFLKYVPLGESTPSQTAWALDALITIQPKSTAAVEKGIERLMMSIHEEDWKTSYPTGAGL
PGNFYSNYHSYRYIWPLLTMSHFRKKYGQG
>A0A6N9IX26|squalene-hopene cyclase|EC 5.4.99.17|Nitrospinae bacterium|TrEMBL
MENMIIEQQNAEASNTAGDVAKKELDRSIERSREFLLSRQTEEGYWVDELEANVTISAEY
IFFMHFTDRLDLAKQEKVVKYLLHQQREDGSWPLFHGGLCDINSTVESYMALKMAGLPAD
REEMVRARQAIFANGGIKNTRVFTKIFLAMFGQISWDVCPAVPVELILFPNWFPFNIYEI
SSWSRGTVVPLSVVRSFEPVHELPEGCDVQELFTKNDQDLDFKPSGLPFTSWRDTFIYLD
RLIKTVGKFPWKPFRKKALRKVEEWTLDHQEEEGDFGGIQPAMFNSLLAFHLLGYSRDHA
ACVKGMEAVDRFMLEKDGRMWMQACVSPLWDTAICSNALLDSGLPSNHPALVKSAEWIIS
KQVVKRGDWQVKNPDAEPGGWAFEFYNELYPDTDDTAEILLFLNRAEVPDNRWKLSECQR
AMDWLLSMQSKNGGWGAFDVDNDKEVLNEVPFADHKALLDPPTVDVTSRIIWMLAKWGFT
KDHPRVKRALEFVKDRQELDGCWFGRWGVNYIYGTFLALNGLKAIGEDMKAPFSRKAVRW
LESHQNEDGGWGETCQSYAEPSLRGRGQSTASQTAWALLGLLAAGEEHSPVVEKGVRYLI
ETQKDSGEFSGSWWEEEFTGTGFPIHFFIKYHMYQHFFPLMALSRYRRSTTESS
>A0A6B2UGH5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID11385|TrEMBL
MTATTDGSTGAATPPATTASAPLHLSPEASEAHEATARATRRAVDFLLDRQSDEGWWKGD
LATNVTMDAEDLLLRQFLGIRDEATTQAAALFIRGEQQEDGTWNTFYGGPGDLSATIEGY
VALRLAGDSPEAPHMRKASAFVRAQGGVARARVFTRIWLALFGWWKWEDLPEMPPELMFF
PKWAPLNIYDFGCWARQTIVPLTVVCAQRPVRPAPFALEELHTDPADPNPAQPAPPVASW
DNVFLKLDKMLHGYRKVAPRRVREAAMRAAATWIVERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVLRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATVALADAGVPGDHPQM
IKAADWMLAEQIVRPGDWVVRRPDLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVAHPDA
TRVDKAVRRAVDWNAGMQSKNGAWGAFDADNTSPFPNRLPFSDFGEVIDPPSADVTAHVV
EMLAEEGLAHHPRTRRGVEWLLKNQESDGSWFGRWGVNYVYGTGAVVPALVAAGLPASHP
AIRRSVAWLGQVQNEDGGWGEDLRSYRDTAWHGRGHSTASQTAWALLALLAAGERDSEQV
RRGIAYLVETQTEDGTWDEPWFTGTGFPWDFTINYHLYRQVFPVTALGRYLNGTGPGEN
>A0A5D4NZY6|squalene-hopene cyclase|EC 5.4.99.17|Rossellomorea vietnamensis|TrEMBL
MEVNIEEQITRIRDRLTAGQQSDGSWHYCFENSLMTDAYMIVLMKSLGIKKKKLTEELGT
RLLSKQTTEGHWKIFNDEEEGNLSATVEAYFALLWSGTAKKADKNMVKARSYILSRGGLD
KVHSMTKFMLAVHGQYPWDRFFPVPAEIILLPSYFPVSFMDFSAYARVHMAPLLLLKSEE
YIRKSFLPPDFSDLLTEKEADLFFRKNERIFVDSLTKGLEAIAAVPANLRKLSKKAAMDY
MLSRIEIDGSLYSYFSSTFYMIFALLSQGYSREHPLIVEAVKALMSYQCKGKGFPHIQNS
TSTVWDTALITHALQTSGMDYGTKPIVMANEYLFKQQHYKKGDWALEAPGTIPGGWGFSH
SNTINPDVDDTTAALRAVKSEAFQDSKKYAAWEKGVKWALAMQNEDGGWPAFEKNKNKEI
LSWVPMDGAEDAALDKSCADLTGRTLEFLCKDAGMIWKSKQVKMGIDWLMRHQEKNGSWY
GKWGICYIYGTWAALTGLSAAGVRNGEDAIVRAKKWLCQIQNSDGGWGESCRSDKEKRYI
SLGSSTPSQTAWALDALIAASDFPTKEIRRGMEALLILIQSDDWRTKYPTGSGLPGRFYI
HYHSYNYIWPLLTLSNYKNKFIEK
>A0A6N7I7K6|squalene-hopene cyclase|EC 5.4.99.17|Streptosporangiales bacterium|TrEMBL
MTTTSPRADVPVSEPPALRAEAAEALGRAREHLLSLQHGDGWWKGELETNVTMDAEDLLL
REFLGIRGERETEEAARWIRSQQRDDGTWGNFYGAPADLSTTVEAYVALRLAGDPIEAPH
MRRAADYIRDQGGVEAARVFTRIWLALFGEWSWDELPVMPPELIYLPTWFPLNVYDWGCW
ARQTVVPLTVVGTLRPRRSLPFTVAELRTGRRPPRAAPAVSWSGAFAGLDRALHVYERRP
IRSVRAAALRRCAEWVIARQELDGCWGGIQPPWVYSLIALHLLGYGLDHPIIKRGLTGLD
RFTIREETPDGMVRRMEACQSPVWDTVLAVTALTDSGLPDDHPSLVRAADWVLGEEVKGP
GDWQVRRPHVAPGGWAFEFDNDAYPDTDDTSEVLLALRRVRHPTRSADIDAAVRRAVAWL
VGMQSRDGGWAAFDADNTQQLCTKLPFCDFGAVIDPPSADVTAHIVEALCGEGLRTSRAV
RRGVVWLLRAQEADGSWFGRWGANYVYGIGAVVPALVAAGVLPEKPAVRRAVAWLERHQN
ADGGWGEDLRSYDDPSWAGRGASTASQTAWALIALLAAGERSSAVDRGVGWLVDHQRGDG
TWDEPYFTGTGFPGDFYINYHLYRLIFPLSALGRYIGGGASSWMQS
>A0A646KB85|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces jumonjinensis|TrEMBL
AGAARRALARSVEYLLGRQDAKGWWKGDLETNVTMDAEDLMLRQFLGVQDDRITAAAARF
IRGEQRADGTWATFHGGPGELSVTVEAYVALRLAGDRPDEPHMETASAWIRARGGTAATR
VFTRIWLALFGWWKWEDLPELPPELIFLPRWFPLNIYDFGCWARQTVVPLTVVSAKRPVR
PAPFALDELHTDARTPNPPKPRAPVLSWSGVFQRADRLLHLYRRAAPRALRRAAMNTAAR
WIVERQENDGCWGGIQPPAVYSLIALRLLGYDLEHPVMRAGLASLDRFAIWREDGARMVE
ACQSPVWDTCLATIALADAGLPADHPALVRAADWMLGEEITRVGDWAVRRPGLAPGGWAF
EFHNDNYPDIDDTAEVVLALRRVAHPEPARVDAAVARAGRWTLGMQSGNGAWGAFDADNT
SPFPNRLPFCDFGEVIDPPSADVTAHMVEMLAHEGRARHPGTRRGVAWLLDHQEPCGAWF
GRWGVNYVYGTGSVVPALTAAGVPAAHPAIRRAVRWLESVQNEDGGWGEDLRSYREEKWI
GRGASTASQTGWALLALLAADERGGEAVERGVAWLAGTQRADGSWDEPYFTGTGFPWDFT
INYHLYRQVFPLTALGRYVHGRPAIAPGRRAR
>A0A523N4A8|squalene-hopene cyclase|EC 5.4.99.17|Nitrospina sp|TrEMBL
MPDQKPEIVENPATAPAATAAPGTPLDRAIGRAKAYLLSLQHADGYWLAELESNATMIAE
YVFFMHFMGIWDPRRVEQCQNTLLKTQQADGGWPLFYGAPSDISTTVESYVALRMAGMSP
KAKAMARARKCIAQLGGVRNARVFTKIFLAMLGQSAWDDLPAMPVEIILLPKSFYFNIYE
MSSWSRGTVVPLTIVAAHQPVWPLKPEHTVPEIFTEADRDLSVQSKNKGLNWPNLFLKID
QLIKFLGKSPVKPFRSWALKRALQWTLDHQEPEGDFSGIQPAMLNSMLAMKLMGYGNDHP
LMVKGYQAIDRFIIDRGDHLIFQACVSPLWDASIACNALMDAGLPGDHPAIVKAGEWMLR
KQVTRPGDWTVKNPNTPPGGWAFEFYNEPYPDCDDTAEILMALDRTGIPDTEWKRKEMQR
AFTWLFSMQSKNGGWAAFDQDNDHELFNRIPFADHGAMLDPPTVDVTGRVLWMLGRINHN
VNDPMVQRALQFIKREQESDGCWFGRWGVNYIYGTWLVLTGLRSIGEDPSQSYIRKAAEW
LKAHQNKDGGWGETCQSYAEPSLRGKGKSTHSQTAWAVMGLIEADEPHSNAVKRGIEYLV
RNQQEDGSWYEDEFTGTGFPRHFFIKYHLYQIFFPLMALARYRNKTG
>A0A7W4JVM9|squalene-hopene cyclase|EC 5.4.99.17|Gluconacetobacter azotocaptans|TrEMBL
MMPNATDTLDLSRPAARDPIVPMADIDRATDRAHAALGRRQNDDGHWVFELEADATIPAE
YVLLEHYLDRIDPALQARIGVYLRRIQGEHGGWPLYYGGKFDISASVKAYFALKAIGDDI
NAPHMARARAAILDHGGAERSNVFTRFQLALYGEVPWHATPAMPVELVLLPRKAFFSMWN
MSYWSRTVIAPLLVLAALRPRAINPHGVHVQELFVTPPSRIRDWIRGPYRSPLGRVFKYV
DKLVRPAERLIPEATRRRAIKAAVDFIEPRLNGVDGLGAIYPAMANTVMMYRALGVPDSD
PRAATAWEAVRNLLVENGEETYCQPCVSPIWDTGLAGHAMIEAASGPDGVRPEETRQKLA
AAAGWLRDRQILDVKGDWAINCPDVAPGGWAFQYRNDHYPDVDDTAVVGMLLHREGDPAN
DEAIERARQWIIGMQSSNGGWGAFDIDNNLEFLNHIPFADHGALLDPPTADVTARCISFL
AQLGHPEDRPVIERGIAYLRSDQEKEGCWFGRWGTNYIYGTWSVLCAYNAAGVAHDDPSM
VRAVEWLRAVQREDGGWGEDCASYEGATPGIYHESLPSQTAWAVLGLMAAGLHGDPAVAR
GMAFLTRMQNADGEWDEEPYNAVGFPKVFYLRYHGYRQFFPLMALSRYRNLASSNSCHVA
FGF
>A0A7V3DIN7|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MKAKGVLSITTASGGADFPSREELQRAVERAQARFLAEQSPEGWWWYELESNVTITAEYL
MLFRFLGIKDPQREQKMARYLLSQQREDGTWGIYFGGPGCVSTTTEAYFALKMAGVSSEE
PCMIKARRFILESGGVEATRVFTRIFLALFGQYPWRRLPSLPVEIILFPGWSPFSVYDFS
SWARATLIPISILLDKKPVVELPEEQGVFELHPRGSTPKVGPKGWLTWEGVFHLMDKLLK
RTEELPIRPLRKRAVRGVEDWILKHQEPTGDWGGIQPAMVNSLLALKTLGYPLEHPVVRK
GLEALERFSIEEEQQLRLQSCISPVWDTPLTCIALLDSGLSKDHPAFVKAAEWLLGRQIW
KEGDWKVKNPGLAPGGWAFEFQNDWYPDVDDSAVVLMALKRMWMDGDPGQDERIRRGIDW
VLGMQSRKGGWGAFDTNNDKQILNRIPWADLEANLDPPTADLTGRVLEFMGHYGFKPGHP
AARAGIRFLKRVQEPDGCWWGRWGVNYIYGTWCVLCGLAAIGEDMTQPYVRKAVRWLKEH
QNWDGGWGETCETYRRPELRGSGPSTPSQTAWALMGLLAAGEAHSQEVARGIQYLLAQQE
ENGTWPEEYFTGTGFPKYFMIRYDNYRNCFPLMALGRYRRALGMD
>A0A6G2U077|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID7805|TrEMBL
MKATTDGSTGAPAPRAPSASDDAAETTAYTPTVVAGDTMAAARHATTRATEHLLAAQDSA
GWWKGTLETNVTMDAEDLLLRQFLGIQDRGTTEAAARHIRAEQRADNTWATFHEGPGDLS
ATIEAYVALRLAGDAPDAPHMAGAAAWIRGHGGIAAARVFTRIWLALFGWWRWEDLPELP
PELIYFPQWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPRHPRPRQPL
APAASWDGLFQRLDKALHLYHKVALRKLRGAAMRSAARWIVERQENDGCWGGIQPPAVYS
IIALHLLGYDLDHPVLSAGLQSLDRFAVWQEDGSRMIEACQSPVWDTCLATIALADAGVP
ADHPQLVKAVDWMLAEEIDRPGDWAVRRPQLQPGGWAFEFENDNYPDIDDTAEVVLALRR
VRHPDPARVDAAVQRAVRWNLGMQSKNGAWAAFDADNTSPFPNRLPFCDFGEVIDPPSAD
VTAHVVEMLADVDRTHDPRTRRGIQWLLAEQEPSGAWFGRWGTNYLYGTGSVLPALAAAG
IPGSHPAVRRAVGWLERVQNDDGGWGEDQRSYQDKKWAGRGASTASQTGWALMALLAAGE
RDSEAVRRGVRWLADTQRADGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGG
PAGASLGA
>A0A7C6E626|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Solibacter sp|TrEMBL
MYAHVSLADALLTAARQAHARGSERLLALQHEPGYWWAVLYGGDTTLESDFVLLELWQHP
PVDGRWDPPTRPLIEKAVASILARQLPDGGFNIYPQGPADVSATVKAYFALKVAGLSPDD
PRLVRARERILALGGLQAANSYVKINLSLFGLYPRRWCPSIPPEMILLGNFIYEMSSWTR
AIVLPLSILHAANPQRPVPAGFTLAELFHPTRPLNWQHDPQLLSWRNFFLALDRGLKFWE
RHGSRRLRELAIRKVERWILERTRYSDGLGAIYPPMMYVVMALDVLGYKRDHPHRVEAER
QFYNLLTDDGERFFFQPCFSPVWDTAIAAFALGSRQDPLTQAALRRAADWLLSKEVRHKG
DWAVKRPHVEPAGWYFEFANEFYPDIDDTAMVLLALRGARASDASRQQAAERRAVQWLLA
MQSSDGGWAAFDVDNDWKPLSHMPFADHNAMLDPTCPDITGRVLEALCRSGLDRGHRAVR
RAVAYLRRTQQAEGCWYGRWGVNHIYGTFLALRGLRAAGESEGEAYILRAGEWLRSIQNA
DGGWGESCASYEEGRYVPAPSTASQTAWALLGLLASGDTASSSVRRGIEYLIETQRQDGS
WHEELATGTGFPKVYYLIYTLYRQSFPVLALAEYLKSQGQQ
>A0A6M0FW07|squalene-hopene cyclase|EC 5.4.99.17|Symploca sp. SIO2E6|TrEMBL
MQTQDRVTTESTVAAAMAKAQDYLLNLQYPEGYWWAELESNVTITSEVVLLHKIWGTDHA
RPLSKAEAYLRSQQREHGGWELYYGDGGEISTSVEAYMALKLLGVPATDLAMLKAKKFIL
EQGGISKTRIFTKFHLALIGCYDWRGVPSIPPWVMLLPEQFLFSIYEMSSWARGSTVPLL
IVFDQKPVYQTNPAITLDELYTEGAGNVQFELPRHGDWTDLFVVLDDAFKLAEDLEVVPF
RQEGLEAAERWVLERQEVTGDWGGIIPAMLNSLLALRSLDYDVTDPIVVRGLAAVDNFAM
ETDQTYLIQPCISPVWDTAWVIRALVDSGISPDHSALVKAGEWLLSKQIVDYGDWVKKNP
QGKPGGWAFEFENRFYPDLDDSAVVIMALDGVQLPQEDQKRAAMARGVAWIASMQCQEGG
WAAFDLNNDADWLNYLPYADLKAMIDPNTADVTARVLEMLGSCNLSIDQSKLKRSLTYLL
SEQETDGSWFGRWGVNYIYGTSGALSALSVINPQQHRLSIQRGVSWLVSCQNTDGGWGET
CRSYDDPTLKGQGDSTASQTAWALIGLIAAGEAITNWETEAIKQGIDYLVATQLPDGSWN
EDYFTGTGFPSHFYLKYHFYQQYFPLIALGRYLRCFEE
>A0A6N1BA38|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus gilardii|TrEMBL
MRASIEAGQRRCQGERALPACFWPDCYNRPTPQYRSRVSRAPVVVPPPPAASRCHRVTRS
DVAEIQIALNGSPQAADLVDHQDRPDSAASFASSFPPLTGSTASADSTDPRLEAAIAHAV
DALIARQRADGHWVFELEADTTIPSEYVLLVHYLGEPADPAREARIGRYLLRRQNADGGW
PLFHGGASDISASVKAYFALKMIGEPADAPAMRRARERILALGGAEASNVFTRTLLALYG
VMPWRAVPLMPVEIMLLPLWFPFHLSKISYWARTVIVPLLVLNTLRPCARNPRRVGIEEL
FRRPSQAARMPGRAPHQGRFWYAVFRGVDVALRVFEPLSPKTLRRRAIEQAERFVRERLN
GDDGLGAIFPAMVNAVMMFDALGVPRDEPAVAQARAALDRLLVEHGDETYCQPCLSPVWD
TSLTCHAMLEAGGERALAAARRALDWLLPLQVLDVRGDWTVRRPHLRPGGWAFQYANPHY
PDVDDTAVVAMALDRAARGDARWQGGVEPALARARQWIEGMQSSDGGWGAFEPENTHSHL
NSIPFADHGALLDPPTADVSARCLSMLAQLGELPANSRAAAQALRYLLDEQEANGSWYGR
WGTNYLYGTWSALCALQAAGLGPEAASVRRAAQWLLSVQNGDGGWGEDGSSYRLDYRGHE
SAPSTPSQTAWALLGLMAAGCRDLPAVARGIDYLLREQRADGLWDEQHFTAVGFPRVFYL
RYHGYARYFPLWALARYRNLQRVGNPANATGTADAAGRMPWGM
>A0A5C8QAL7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. IB2014 016-6|TrEMBL
MTATTDGSTGAVGPRAAEASEPSDTTPVTNDVAEAARRATARSVEHLLGRQDAQGWWKGD
LETNVTMDAEDLLLRQFLGVQDARTTEAAGRFIRGEQRADGTWATFYGGPGELSTTIEGY
LALRLAGDRPDDPHMARAAAWIREHGGIAESRVFTRIWLALFGWWKWDDLPEVPPELIFL
PKWFPLNIYSFGCWARQTIVPLTIVSALRPVRPAPFALDELHTDVSRPNPAKPLAAATSW
DGIFQRIDKALHLYHKVAPRVVRRTAMNAAARWIVERQENDGCWGGIQPPAVYSVIALHL
LGYDLGHPVMRAGLESLDRFAVWREDGSRMIEACQSPVWDTCLATIALADAGLSPDHPAL
VKAAGWMLDEQIVRPGDWAVRRPGLAPGGWAFEFHNDNYPDIDDTAEVILALRRVRHPDT
ARLDTAVERGARWTLGMQSRNGAWGAFDADNVSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAYEGLAQHPDTRRGIEWLLTEQEADGSWFGRWGVNYVYGTGSAVPALVAAGIPASHP
AIRRAVGWLESVQNDDGGWGEDLRSYREEKWIGHGSSTASQTAWALLALLAAGRRETPAV
ERGVAWLVAAQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPSPDRT
PARAERLGAGRTGSVKERRPDTRSADSRADSYKGA
>A0A552DRE2|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa Ma_SC_T_19800800_S464|TrEMBL
MQIQEKISAIAAKTAKAIELSQNYLLSTQYPEGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYGWLGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKSNNWSDIFLWLDGLFKWAEKTNLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDIDDPIVARGLKAVDNFAIE
TDNTYCVQPCVSPVWDTAWVIRALIESGLNPAHPAMIKAGQWLIAQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKGVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYHQQLQKGANWLSGCQNIDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A292YZI0|squalene-hopene cyclase|EC 5.4.99.17|Pseudonocardia sp. N23|TrEMBL
MTLTAPEHLATRTPQASLDAAVAFLRAGRHPDGWWQGELETNVTMDAEDLLLREFLGIRT
DTETLEAARWIRSRQRADGSWATFQDGPADLSTTIEAWVALRLAGDDPADPHMRSAQTFV
RAEGGLERSRVFTRIWMALFGAWSWDELPDMPPELIFLPTWFPLNVYDWACWARQTVVPL
TVVATLRPCRPLPFGVDELRTGAAAEPLAKPWTWTGAFQRLDRVLHAYSRRPLRGVRRLA
MRRAAEWVLARQEADGSWGGIQPPWVYSLLALHLLGYPLDHPAVAAGIRGLDRFLVREET
PEGTVRRLEACQSPVWDTCLAVTALLDAGVPADDPDVLAATDWMLAEEIPDVRGDWSVRR
PDLAPGGWAFEFDNDGYPDTDDTAEVVLALRRVTHPDPQRLRAAVDRGVAWTIGMQSRDG
GWGAFDADNTRVLVTKLPFCDFGAVIDPPSADVTAHVVEMMAAEGLAATEECRRGVDWLL
AAQERDGSWFGRWGANHVYGTGGVVPALVAAGIDADAPPVRRAVGWLERHQNDDGGWGED
LRSYEDPSWIGRGASTPSQTAWALLALLAAGESSDAVERGVRYLVDTQLPDGSWEETLYT
GTGFPGAFYIRYHLYRMVFPISALGRYVNGHSS
>T2B0I5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
PVWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQYW
NDYYPDVDDTAVVVMALHRADSVRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQH
IPFADHGALLDPPTADVSARCLSMVAQMGYGPDNQAVARAIRYLKRGQEANGSWYGRWG
>T2B092|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIFMEKAANWLVKRQILDVIGDWGANVHGVRPGGWAFQY
WNDYYPDADDTAVVVMALHRADPDCYSEAIARGAEWIIGMQSGNGGWGAFDVNNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGLDNQAVARAIGYLKRGQEVNGSWYGRWG
>T2AZX6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANG
>T2B0K9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKIIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSRNGGWGAFAVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWFGRWG
>T2B001|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSVRCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWFGRWG
>T2AZZ6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDAAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWFGRWG
>T2AZE9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIEAEKNRQSTEIENALNWLKKQQLSNEPGDWRIQKPELAGGGWAFQY
SNYYYPDLDDTSMVAWAMHRVNSKKYVAPIQRAANWVAGMQSRSGGFGSFDINNTHFYLN
EIPFADHGALLDPPTADVTGRAIALLSLADKEKYAKNIKEGINYIKSEQENDGSWYGRWG
>T2AZY9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSIATIALREAGVSADDPAIRKSVSWLLSKEVREPGDWSVRNKSCEPSGWFFEFN
NRYYPDVDDTSMVVMALRRSLPAMATEGWDADFLLDKWSPHAADKDAVAVLSVRINSPED
LRVGMESITPQLSAIWRGARWVLAMQNKDGGWGAFDANNTRELYTQVPFADHNAMIDPSS
ADLASRMLEMFADLNVPCEHPALQRALKYIRDEQDPAHCWYGRWG
>T2AZT3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAICSNALLDSGLPTDHPALVRAGKWIVSKQATKRGDWQVKNPKAEPGGWAFEFY
NELYPDTDDTAEILLFLNRVEILDNRWKLSECQRAMDWLLSMQSKSGGCGAFDVGNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGKWGFNKQHPQVKR
>T2AYR4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTCLSLTALSEGGAPNDHPAVRQAVDWLFDNQIFVNGDWSKNAKGLESGGWAFQYE
NDKYPDVDDTGMVLMALLRAGAHEKDAKKKRLNQAPNWVLGMQNPDGSWGAFDIGNNCGY
LNNIPFADHGALVDPGTADLTARCIELLSMVGYGSESPVVTRALRFIREDQEEDGSWYGR
WG
>T2AXJ8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDDPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGRW
G
>T2B0H0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
GDWKFKNPTDAGPSGWAFEHKNKWNPDVDDTAMVLMALRRVPGSDRRRRDIAVERGLRWM
LTFQCKDGGWGAFDKDCTKDILNKVPFADHNAMLDPECADITARILEFLGQGGYSTDNQQ
VKKAIRFLRDNQVEDGSWYGRW
>T2AZV3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLATHAMLEANLSSGPRILENDSASKACKWLEKLQIKDCAGDWAVRRPNLRPGG
WAFQYHNDYYPDIDDTAVVAMTLHRTGNKIYEPALLRAAEWIIGMQSKNGGWAAFDADNE
YHLLENMPFADHGALLDPPSVDVSARCISFLTQLGYDQTNGTIKRGIEYLKKNQEEDGSW
FGRWG
>T2AZP0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTALVSQAPIEAEKNRQSTEIENALNWLKKQQLSNEPGDWRIQKPELAGGGWAFQY
SNYYYPDLDDTSMVAWAMHRVNSKKYVAPIQRAANWVAGMQSRSGGFGSFDINSTHFHLN
EIPFADHGALLDPPTADVTGRAIALLSLADKEKYAKNIKEGINYIKSEQENDGSW
>T2AXU1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGIACNALMDAGLPKDHPALIKATEFFFRKQVVKRGDWQVKNPNAESGGWAFEFY
NELYPDNDDTAEILMAIHSIEFPDLRYKLKESQRALSWLLSMQSKNGGWGAFDQDNDQEL
FNAIPFADHNAMLDPPTVDVTSRIIWLLGILGYSREHPQVKKAIVYIISDQENDGSWYGR
WG
>T2AYJ4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHISTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDVNNTHFYL
NEIPSADHGALLDPPTADVTGRAITLLSLADKKIYAKNIKDGVDYIKSEQEEDGSWYGRW
G
>T2B049|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAIAANALLDSGLPSDHPALVKAGEWIINKQVIKRGDWQVKNPGAEPGGWAFEFY
NELYPDTDDTAEILLFLNRIEIGDNRWKLSECQRAMNWLLSMQSKSGGWGAFDVDNDKEV
LNEIPFADHKALLDPPTVDVTGRILWMLSKWGFKKQHPQVQRAIQFIKERQEIDGCWFGR
WG
>T2B0D3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTCIAQLALLESGIDPEDPMVQSSARWLMDKQIYAAADWQVRAKGTRPGGWSFEFD
NLIYPDIDDASIVVMALDQVRLPEAEEPRRADSIQRGVEWMTGMQSKNGGWAAFDKDNNK
KYLTKIPFSDFGEALDPPSVDVTAHLLEMYGRLGYTKEDRAVDRGFAYVISEQEEDGSWF
GRWG
>T2AZL0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGFNGLSLLESGLTLKDPSIQKACKWLEKKQILEIKGDWIVNNKNLLPGGWAFQY
ENDFYPDVDDTAVIVMFLERAGYQNKKRLEIACNWIIGMQSKNGGWGAFDKDNTYHYLNN
IPFADHGALLDPPTADVSARCISMLSQINKKNYKKIIQKGVKVLKNEQENDGSWFGRWG
>A0A5C4WBQ7|squalene-hopene cyclase|EC 5.4.99.17|Nonomuraea phyllanthi|TrEMBL
MTTLGTPTTGETPAIRETPDALGTPGTLTGPITGPITGAEQALQAACDHLIGLRSAEGWW
KGELQTNVTMDAEDLLLREFVGIRTEEDTAEAARWIRSEQRADGTWANFHGGPADLSTTI
EAYAALRLAGDPPDAEHMRAAARQVRDLGGIEASRVFTRIWLALFGEWEWRDLPVMPPEM
IYLPSWFPFNVYDWACWARQTIVPLTVVTAYRPVRPLPFRLPELRTGLRPERARRGGWEA
AFGALDKVLHRYERRPARGLRRAAVRRAVEWIVARQEADGSWGGIQPPWVYSVIALHLAG
YHHDHPVMRKAIGGLDRFTIRDEKGRRLEACQSPVWDTALAVNALLDAGTPADHPAVTGA
ADWLLREEITRAGDWAVRRPALAPGGWAFEFDNDGYPDTDDTAEVVLALRRLDRTGIRPA
VERGVRWMTGMASRDGGFAAFDADNDRALITKLPFCDFGAVIDPPSADVTAHVVEALAKE
RPHSLALRRGVVWLLRAQERDGSWFGRWGANHVYGTGAVVPALVAAGVRPWHSSVRRAVA
WLEHHQNDDGGWGEDLRSYRDPSWIGRGASTPSQTAWALLALLAAGERSQAVERGVRWLV
GNQRPDGTWDEPYFTGTGFPGDFYINYHLYRLVFPISALGRYLRRDGTPAGPEAP
>A0A380XSM2|squalene-hopene cyclase|EC 5.4.99.17|Cytobacillus firmus|TrEMBL
MTNTAAGMKRLIAALRKDQSHDGSWSYPFETGISTDAYMIILLRTLEMHDEKLIQGLAAR
ILSKQEENGAWKLFKDEPDGNANATLEAYYGLLYSGYIEKEDARMKAARKFILEHGGMEN
ANIFTKIMLSTTGQYPWPESFPIPVEIMLLPLSFPFNFYQFSVYGRVNLAPILILSEKKF
SIKTKNSPDLSDLLLTRAQWEVQREYRSFLSFIQEGVEELLGLPEQLHSLAMDRAKEYML
ERIEPDGTFYSYFSSTFLMIFALLALGYSKDEPVIKNAVAGLKSLRTDIDGLPHMQYSNA
SVWNTSLINTALQLAGVSPDDPAVKKANTYLLKRQHEKYGDWAIHNPHGKPGGWGFSDVN
TLNPDVDDTTASLRAIARSAGDNSEYQGSWDRGIQWLVSMQNDDGGWPSFERNTENPWLA
ILPIEKGEYMFGDPASADLTGRTLEFLGNYTNLAAADPLIKNAVNWLLDHQEQDGSWYGR
WGICYIYGTWASVTGLIAAGHSNHPSVRKACDWLKGIQNEDGGWGESCLSDSQKSYVPLN
ASTLTDTAWAVDALIAAEDQPTEQIQKGIQYLLNSIDKEDWTTDYPKGQAMAGSFYIHYH
SYRYIFPLMALAHYHGKFGK
>A0A534PAW5|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MPARRARIGPAPDARSRGAGKGRALVPGRSRSQEERVVIGRERDFEAAQLDLIVERAQSW
FFREQFDDGYFWAELESNATMDAEYLLLTHFLGARDESIWRGVAQDVRNYQRADGSWALY
HGAPGDLSTTIECYFALKLAGDSPDAPHLRKAREFVRERGGIARARTFTRIWLALFGEFP
WSDLPAMPPELMLLPDRAPLSIYRFSSWARGTIVPLLILMNERPVRPVPRAARVAELWVE
GAGPTPARDPIDGAFLALDRALRIYDRFPVHPLRRRALDTAESWILSHQEADGSWGGIQP
PWVYSLMALSVRGHSLRHPALQKGLEGMHGRWMIRRPDGTLRVQACLSPVWDTGLGLLAL
CESGVPRNDAHVQRAAKWLLREEIRVPGDWCVQVKGVEPSGWAFEFENDLYPDVDDTAVV
LLALERAGAVDPALRKRAIRWMLAMQSANGGFAAFDKDNTSRLPALIPFADFGEMIDPPS
ADVTAHVLEALAAFGYQKRNPAVRRALAYLRDQQELEGSWFGRWGVNHLYGTGAVLPALA
ALGERPDGLALRRAVRWLEERQNRDGGFGETCASYVDRAARGRGASTPSQTAWGLLALVA
AGRSETAAAASAALFLAERQRSDGAWDEEEFTGCGFPGYGVGEERGARIREGAELSAGFL
IRYHLYRNCFPLLALGRYRSALSVRARGAA
>A0A6G2KT43|squalene-hopene cyclase|EC 5.4.99.17|Acidimicrobiia bacterium|TrEMBL
MGVEQCLARARDRLLSLQDIEGWWKDELETNVSIEAEDLFLREFLGIADPEVTRQTANWI
RHSQRADGTWATFYQGPADLSVTVEAYWALRYAGDPVDADHMTKAADYIRSEGGLERSRV
FTRIWMALFGLWRWEDLPALPPEVILLPKQVPLNIYDFACWARQTVVSLTVVGAHRPVRS
MGISLDEIRTGATPPERELAPPGTVARRFQRLDQALHHYENRPHRRLREWSLRRAEQWII
ARQEADGCWGGIQPPWVYSLLALYVRGYSLHHPILAQGLAGFDAWTIVEDDMRRLECCQS
PVWDTCLALIALADAGVDPDDSQMEAGARWLMDQEVQVVGDWAEQRPHLAPGGWAFEFEN
NFYPDLDDTAEVALALRRINHTDARKVNRALDRAVEWVQGMQCQDGGWAAFDADNCSPLV
AELPFCDFGEVIDPPSADVTAHVIEMLCELDGDGLRLKVDPVVVDRGVQWLSDEQEDDGS
WYGRWGANYIYGTGAAIPALISAGIPTDDARVVRACRWLESVQNNDGGWGEDMRSYTDRE
WRGRGESTPSQTAWALLALIAGGQASGEAARRGVAWLVENQRRDGDWDEPWYTGTGFSGD
FYIRYHLYRLVFPVMALGRWVRAIEDEA
>R9W099|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAQVLSPVCDCGLARNDPRMVKGAEWLLSKEITHKGDWSHNVKIENASSWCFFYN
NDHQPDCDDTAEVLLALKAADTPHERRQYEASQRAIEWIFAMQCRSGGWASFDKDNTKKI
FESIPFADHNAMIDPPTVDITGRILEMLAQYGYSRRDKRVEKAIQFILRQQEPDGAWFGR
WGVNYLYGTFLVLRGLRAMDFDTNEPAVQQAAEWIRMVQNADGGWGE
>A0A2N9CZQ3|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cenocepacia|TrEMBL
MNDLTEMATLSAGAVPAGVDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANSVMMYAALGYAEDHPNRAI
ARKSVEKLLVVHDDEAYCQPCLSPVWDTSLAAHALLETGDARAQEAVLRGLEWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLTQSDTYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGYEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLV
AQQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A5M8GYA7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces parvus|TrEMBL
MTATTDGSTGAANITGAPADDPTDTRTAANDVTDIARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPGDLSATIEAY
VALRLAGDRPDEPHMARASGWIRDQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHADPDHPNPPRKLAPRASW
DGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLDHPVMKAGLASLDRFAVRREDGARMIEACQSPVWDTCLATIALADAGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARLEAAIARGVRWNLGMQSRNGAWGAFDADNTSAFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLASHPRTREGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALITAGLPAGHP
AIRRAVDWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDTASV
TRGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFADRP
DAAEGV
>A0A4Y6UBL0|squalene-hopene cyclase|EC 5.4.99.17|Swingsia sp. F3b2|TrEMBL
MNESDVVEQAVDAAHGALQAMQKADGHWVFELEADATIPAEYVLLEHFLDRINPELERKM
GAYLRRIQGAHGGWPLYEDGDFDLSASVKAYFALKALGDDPEAPHMRRARTEILRHGGAE
RANVFTRIQLALYGEVPWDAVPVMPPEIMLLPSAGFFSVWNMAYWSRTVIAPLLVLCDLR
PIAVNPRGVHVQELFCTPPAQIKDWIRGPYRSWWGPVFKGLDSALRPMVRHFPRKLHKKA
MRACLRFIAPRLSDGGLGAIYPAMANVVMMMRALGVPDSDPRAKQAWQALQDLMVDRGHE
AYCQPCVSPVWDTGLAGLAMLEASDGPRATLPEATRRQLASTAAWLRSQQILDVVGDWAV
NAPGLRPGGWAFQYDNAYYPDVDDTAVVGMFLHRQDPVENAEAIARAREWIIGMQSRDGG
WGAFDIDNDLDVLNHIPFADHGALLDPPTADVTARCVSFLAQLGHAEDKPAIERALAWLR
KEQERSGSWFGRWGTNYIYGTWSVLCAFNAAGVPPEDPAVQKAVAWLERVQRPDGGWGED
CASYEGAPEGVYEESLPSQTAWALLALMAAGRHGTKAVERGVAWLAAQQDGEGRWHEKPF
NAVGFPKVFYLRYHGYKQFFPLLALARYRNLEDSNTGRVEHGF
>A0A533ZT59|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
MKRLLGLLTNWSEKILSVAPERVQRQARQKANRLLRIVGGNPGVFLSAPAVQRRHDPGQG
SVQSVTHKGDAVDHAIKRSQQWLLQRQTEAGYWVYELEADTTLTAEYLMLRRFLGLVDAE
KERKAVRYLLGAQLPEGGWPIYDGGPPEISASVKAYFALKLCGMSATEPVMEKARTMILS
KGGVVRANVFTKIALALFDQYDWRGIPSMPAEIVLLPPRFIFSLYALSYWSRVVLTPLLI
IFQSKPVCGIPKEQGIDELYCTARELVDFRREPPFRKDRRWFTWRNFFITLDGVLRFYER
VVPQGLRKKALARAAQWMLERMEGDGGLGAIYPAMANSVVALRCLGYEVDHPLLRKALHE
IEALEVHEGGALHLQPCFSPVWDTPLAINSLIESGLPQDHPALVKAARWTLSRQCRKLGD
WIMSSPKAEPGGWYFQFENECYPDNDDTAVVVMALSKLTMPEWGAQLDGVRRGMRWTLAM
QGSDGGWGAYDKDNDKMFLNQIPFADHRALLDPSTADLTGRELEMLGALGFDIKHPAAVR
ALRFLRKTQEADGSWYGRWGVNYIYGTWSVLAGLKAIGEDMQAEYVRLAVAWLVSKQNPD
GGWGESCLSYAEADAHGVGESTPSQTAWAVIALLCAGEVDSLSVLRGVHYLLRQQHAQGA
WPERAHTGTGFPRVFYLRYHGYSQYFPLWALSMYRSLKARGRTRADELREQNRQHGRFRF
EA
>A0A533YRM0|squalene-hopene cyclase|EC 5.4.99.17|Nitrospirae bacterium|TrEMBL
MKRLLGLLTNWSEKILSVAPEHVQRQARQKAKRLLRLVGGNPNLFLSDPAVQRPHDPGQG
SGQSVAHKGDAVDEAIKRSQQWLLQRQAEAGYWAYELEADTTLTAEYLMLRRFLGLVDPE
KQRKAVRYLIDAQVLEGGWPIYYGGPPEISASVKAYFALKLCGVSAAEPFMEKARTMILS
KGGVVGANVFTKIALALLDQYDWRGIPSMPVEIVLLPPRFLFSLYALSYWSRTVLTPLLI
IFHYKPICRIPKEQGIDELYLTAREWVNFRCEPPFRKDHRWLTWRNFFITLDGVLRFYER
VVPQGLRKKAVARAAQWMLKRMEGDGGLGAIYPAMANSVVALRCLGYEVDHPLVRKALRE
IEALEVHEGDAMHLQPCFSPVWDTPLTMNALIESGLPQDHPALVKAARWTLSQQCRKVGD
WIVSSPTAEPGGWSFQFENEFYPDNDDTAVVVMALSKIKMPEWDAQRDGMRRGMRWTLAM
QGSDGGWGAYDKDNNRMFLNQIPFADHRALLDPSTADLAGRELEMLGALGFDLRHPAAVR
ALRFLWKNQEADGSWYGRWGVNYVYGTWSVLAGLKAIGEDMQARYVRRAVAWLVSKQNPD
GGWGESCRSYAEADAHGVGESTPSQTAWALLALLCAGEVDSLSVLRGVNYLLRQQDAQGF
WSECKHTGTGFPRVFYLRYHGYCQYFPFWALSMYRSLKTRGRSRADENREQNRQHGRFRF
EA
>A0A522S014|squalene-hopene cyclase|EC 5.4.99.17|Rhodanobacteraceae bacterium|TrEMBL
MVPDASFPQPDTTGRSTPAARDRLAVAVDAARTRILGYQHPVGYWQFNLEADCTIPAEYI
LMLHYFGESDRLLEARLAEYLRAHQCRDGGWPLYPGGALDVSCSVKCYFALKLVGDRADS
VHMTRARQAILAHGGAARSNVFTRIALALFGELPWRGVPFLPVETILLPRWFPFNLAKVS
YWSRTVMVPLSILTTLKPHAANPRGIHISELFLAPPAQEHHYFHARSLLNRVLLAAEEVV
RHLEFLIPSRVRRHALKRAEQWILARRNGEGGLGGIFPAMVNAYEALALLGYPREHPARQ
ETRRAIDDLLVVHGHSAWCQPCVSPVWDTALTCLALQEDPDAPAAATRRALDWLVQHQLR
DEPGDWRAYRPNLRGGGWAFQFKNDAYPDLDDTAAVARALRQAPDHAPFADAIERAADWL
CGMQSKNGGFGAFDADNNHQWLNQIPFADHGALLDPPTSDVSGRVLTLLALLQRPQDAAA
RARTLRFLLDEQTPEGAWFGRWGTNYLYGTWSVLVALRLAGLPPDAACIRRAVTWLKSVQ
QADGGWGEGNDSYLNPELRGRGARSGATQTAWAMLALLDAGEGASPAVARGADYLLRTQV
DGEWHDGRFNAPGFPRVFYLKYHGYSRYFPYWALVRYRNVTVAGRH
>B7IRK2|squalene-hopene cyclase|EC 5.4.99.17|Bacillus cereus (strain G9842)|TrEMBL
MLLYEKVYEEIARRTTALQTMQRQDGTWRFCFEGAPLTDCHMIFLLKLLGRDKEIEPFVK
RLASLQTNEGTWKLYEDEVGGNLSATIQSYAALLASEKYTKEDANMKRAEMFINERGGVA
RAHFMTKFLLAIHGEYEYPSLFHLPTPIMFLQNDSPLSIFELSSSARIHLIPMMLCLNKR
FRVGKKLLPNLNHIAGGGGEWFREDRSPVFQTLLSEVKKIITYPLSLHHKGYEEVERFMK
ERIDENGTLYSYATASFYMIYALLALGHSIQSPIIQKAITGIASYIWKMERGSHLQNSPS
TVWDTALLSYALQEAQVPKASKVIQNASAYLLRKQQTKKVDWSVHAPNLFPGGWGFSDVN
TMIPDIDDTTAVLRALARSRGDENVDNAWKRAVNWVKGLQNNDGGWGAFEKGVTSRILAN
LPIENASDMITDPSTPDITGRVLEFFGTYAQNELPEKQKQSAINWLMNVQEENGSWYGKW
GICYIYGTWAVLTGLRSLGIPSSDPSLKRAALWLEHIQHEDGGWGESCQSSVEKRFVTLP
FSTPSQTAWALDALISYYEKETPIIRKGISYLLSNPYVNEKYPTGTGLPGGFYIRYHSYA
HIYPLLTLAHYTKKYRK
>A0A849XXS0|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobiae bacterium|TrEMBL
MKEVLLAQERSRDWLLAQQDPEGFWVGELEGDTILESEYALYLHYMGWGDAETFRLLANH
ALRHRNAEGGWAIFPDGPTNVSATVKCYILLRLAGHSPDEEMMRGIRDLILRGGGIVKVN
SFTKINLALVGAFPWEGVPAIPPELILFPKNFYYSIYSMSAWSRTMLVPLAIVEHFKLTR
PLPFQVDELYAGGRATADIHLSWSARAVSWHNFFLAWNHIIKWWQKTPVHPFRGTALTRC
HRWLLERLEHSDGLGTIFPAMVNSIFALTALGYPAEHPLVQREKKQLERLTIREGDTLRL
QPCFSPVWDTAWSTLILRESGLPANHPALVRAAQWLLSKETTIVGDWAIKNPQPEPAGWY
FEFRNEWYPDVDDTIVVLRALKLVDLPDRAAKERAIQRGVRWVLGMQCRNGGWAAFDKDN
TRRLYTEVPFADHNAMIDPPTADITGRVLECLADFGFTAASPECRRAIAFIRKDQCADGS
WFGRWGSNYLYGTWQVLVGLARIGEDMRQPMVRRAVRWFESVQNPDGGWGESLASYEDPT
QKGRGPSTASQTSWAILGLLAAREFNSRAVERGIAWLAARQNADGSWTEKEWTGTGFPKV
FYLRYHLYRAYFPLSALTAWVELHRDHARHPAVQSLTTAAARQAAPVEARRAESTA
>A0A836TRV7|squalene-hopene cyclase|EC 5.4.99.17|Thiotrichaceae bacterium|TrEMBL
MTLETHSDNAHNQSPAESHSKTSSVNLDDAIQSAKNKLLEQQHNDGHWVYELEADCTIPA
EYILMNHFVDEIDDETEHKIAQYLRDQQNDEGGWSLYTGGDFDISCSVKSYYALKISGDS
PHEEHMIRAKNMILNHGGAANSNVFTRILMALFEQVPWRATPFIPAEVIILPKWFPFHID
KVSYWSRTVMVPLFILCTIKPAAENPRGIDIRELFITAPEDEQNYFKVTSPLTRAFLILD
HLGRLAEKIVPNFVRQYSIRKCEQWCLARMNEEHGIGGIFPAMVNLFVSLVILGYPKDHP
QRKLARQAIDNLLVKRGNTLYCQPCVSPIWDTCLAGQAMIETETEENITPEIEHALDWLK
DRQLSDEPGDWRIPRPNLAGGAWAFQYSNYYYPDLDDTAMVAWAMHRTKNPKYAEPIQRA
AHWVAGMRSSGGGFGSFEINNTQYYLNAIPFADHGALLDPPTADVTGRSIALLSLADKEK
YASIIKDAVNFLISDQEENGSWFGRWGTNYIYGTWSVLTALEIAEEDPQQEFIRKAVSYL
QCMQNEDGGWGESNDSYYPPKHRRPFKSTAYQTAWALLSLLAVGEAETETVKKGIQFLLS
SQTSDGHWYDDSYTAPGFPRVFYLKYHGYTKYFPLWALSRFRNLTQNKS
>A0A538LCY8|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MARAAAVVRGLGGVAATRVFTRLWLALFGLWSWDDLPALPPEVVLLPTWCPLNIYDFACW
ARQTIVALTVVAAHRPVRPLTFRLDELDAPGRVAGRAEGVASVAGRLLDRVLRSYERRPL
GVLRRLALAKAERWIVRHQEQDGSWGGIQPPWVYSLMALDLLGYPPGHPVMKKGLEGLES
FTVVGDGRRRLEACQSPVWDTALAVLALTDAGLPGDHPALVRAADWLLAHEVRTRGDWAV
RRPRLDPGGWAFEFANELYPDVDDTAVVVLALRRVRHPDPARVEGAVERARHWTLGMQSE
GGGWGAFDVDNTRELCRRLPFCDFGEVIDPPTADVTAHALEMLAGEGLADDRRVVDGARW
LLAQQEFEGSWFGRWGANHVYGTGACLPALVATGLPTDAVALRRAERWLESHQDPSGGWG
EDLRSYDQGSWRGRGEPTASQTAWALLALLALRAGPDVSAATERGVDWLVRTQQADGSWD
EPWFTGTGFPGDFYINYGLYRLVFPVMALGRYLGAR
>A0A537XD48|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MAVRTRDTRPGAAPSPGQAPVRPVAPQELDRARARARDHLLGLQSEDGWWRGELQTNVTM
DAEDLLLREFLGARDERATELAARWIRSQQREDGSWTKFYGGPGDLSTTIEAYVALRLAG
DNIDAEHLARARGFILGRGGLESARVFTHIWLALFGLWPWEQVPALPPEMIFLPRWFPLN
PYDFACWARQTVVALTVVRSLRPARPLGLGVDELRSGRPPIKRRAPTWRGRLLAWLDAAL
RLYERRPLGWLRRRALDRVEDWIVERQEEDGSWGGIQPPWVYSLIALSLRGHSLEHPVMR
RGLGGIEGFLIQDELGRRLEACQSPVWDTALAVTALTDAGLVPDHPALVRAADWLLGEEV
RVRGDWAVRRPGLPAGGWAFEFANQHYPDTDDTAEVVLALRRVRHPAPVRVHGAVARAVA
WAQGMQSSDGGWGAFDADNARRLVRELPFCDFGEVIDDPSADVCAHMLEMLAVEGRAGTP
PARRGAAWLLEAQEPDGSWFGRWGVNYVYGTGAVLPALRAHGVPATDPRLRRAGWWLESV
QNADGGWGEDPRSYDDRAWAGRGQSTASQTAWALLGLHALGERTPAVERGLRWLIEHQRE
DGTWDEPWYTGTGFPGDYYINYHLYRLLFPLSALGRWGSAT
>A0A538H8Y6|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MTIAPERLETRVDTAVERATARLLELQHPEGWWVGELESNATMIAQHLFWNHVLGLRTPE
LDRKIANELLARQREDGTWSIWFEGPPDLSTSIEAYAALRLAGVDPGPRARDFITAQGGV
RRARVFTKCFLALLGQWPWQWIPTVPPELILLPPWAPLSVYDFSCWARQTIVPLSVVMAL
RPVRPAAIELREIGARPWPSRPVRPRSALRRRAIAVAERWVRERQEADGSWGGIQPPWVW
SIVMLAALGHGFEDETLRRAVEGWRGFTVDEGDRLRPEACQSPVWDTALAVLALREAGVS
ADHPALRSAGDWLLREEVTVKGDWAVRRPDLAPGGWAFEFENDLYPDVDDTAVVALALRE
LGLGEEAVRRGLEWIVGMQSSGGGWGAFDVDNDKLWLYRIPFCDFGKVTDEPSADVSAHA
LEVLAQEPGYEASVERGLDWLLREQEDDGSWFGRWGVNHVYGTGAALPALEACGIEPEHP
AMRRAVEWLDSVQNGDGGFGEDILAYGDDARRGRGVSTPSQTAWALLAYAAAGEQRRLSA
ERAATYLCVAQLADGDWTEEHYTGTGFPLDFMIRYHLYRLHFPLMALGRLRERMNA
>L1KPL1|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces ipomoeae 91-03|TrEMBL
MTATTDGSTGAPPPRAASASDTDHDTPAAAGLQDAAAHAMRRATDFLLARQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDEKTTQAAALHIRGEQRADGTWATFHGGPPELSTTIEAY
VALRLAGDDPDEPHMARASAWIRQRGGIAASRVFTRIWLALFGWWKWDDLPEMPPELIHF
PKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPGRPNPPKSLDPLGSW
EGAFQRLDKVLHGYHKVALKRLRKAAMNSAARWIIERQENDGCWGGIQPPAVYSIIALYL
LGYDLGHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQL
VKAADWMLGEEIVRPGDWSIRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHPDP
ERVEKAVRRGTRWSLGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIEWLLAEQEPNGSWFGRWGVNYVYGTGSVVPALVAAGLPASHP
AIRRAVAWLETVQNDDGGWGEDLRSYRDAAEWGGKGASTASQTAWALLALLAAGERDAKA
TERGIEWLAQTQGEDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPAVLK
ATGS
>A0A836X995|squalene-hopene cyclase|EC 5.4.99.17|Methylococcaceae bacterium|TrEMBL
SLFTGGVEDISCSVKVYFALKLAGDEPTSPHMVNLRNYILGQGGAAKANVFTRITLAIFE
QIPWRGVPYIPVEIMLLPKWFPFHLDRVSYWSRTVMVPLFILCTLKAKALNPKKINIAEL
FVTPPYEEKKYFSNDTLLSKIFLGLDKLGLITRPLIPKRLTQKSFDLALNWITERLNGED
GLGGISPAMIAAHQAMLLLDLPRDHPDVKTARKAIDKLIVFRDQEAYCQPCLSPVWDTGL
AALALQEADLQGTRQSREKAYNWLKTKQLDKQAGDWQIQKPHLNGGGWAFQFENPHYPDV
DDTALVAFAMANANDLNNLEEPIHRATQWTAGMQSKNGGFGAFDCDNTDYYLNHIPFADH
GALLDPPTADVSARCAMLLGHQLNSHPEYQKTLDKTITYLRKEQESDGSWFGRWGTNYIY
GTWSVLLGLEQTQVPKNDPMYTQAVQWLKSVQNNDGGWGEDNYSYHDDSTRGQAESSTSF
QTAWALLGLLAAGEVNSPEVKNGINYILSHQTQEGLWADPGFTAPGFPKVFYLKYYGYDK
FFPLWALARYRNELQKL
>A0A7X3K7C6|squalene-hopene cyclase|EC 5.4.99.17|Massilia sp. NEAU-DD11|TrEMBL
MRYSSFRSMAQAGAVEAERTLTRRARLEPAIDAALAAVLADQRDDGHWVYELEADVTIPA
EYVLMVHYLGETPDTALERKIGTYLRRRQGDHGGWPLFHGGAFDPSASVKAYFALKMIGD
PPDAPHMARGRSAILDHGGAERSNVFTRMLLALFGEVPWSAVPVMPVEIALLPRWAPFHL
SKVSYWTRTVLTPLLVLGALRPRARNPRAVGVPELFLAPPDGLGLAPRAPHQDRMWFALF
RALESQMRLLAPRLPARLRRRAVEQAAAFVRARLNGEHGLGAIFPAMVNAVQMLDVLGLA
PDAPESSAARRAIDRLLVDHGAEAYCQPCLSPVWDTALMCHALLETGTPRALDAARRGLD
WLLPLQILDQPGDWAARRPDVRPGGWAFQYENACYPDVDDTAVVAMAMHRAAHLEPWPLP
DRYADAVARAREWIVGMQGRRGGWGAFEADNTHDYLNHIPFADHGALLDPPTADVSARCL
SMLAQLEPGACARRRSPAARALGWLLRRQEANGSWYGRWGVNYVYGTWCALCALAAAGLP
PEAPPVARAARWLAYVQNPDGGWGEGGDSYRLDHTGHAWAPSTASQTAWALLGLMAAGAV
ETRAVTRGIAWLVDHQRADGLWDEPQHTATGFPRVFYLRYHGYARYFPLWALARYRNLRA
GGSGRVAFGM
>A0A4Y9UVL0|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. MOS001|TrEMBL
MDSVNATSREALESGVLESSIASATQGVLGFQQSDGHWVFELEADCTIPAEYILLRHYLA
EPVDAVLEAKLGNYLRRVQGAHGGWPLVHDGEFDMSASVKSYFALKMIGDSVDAPHMVRA
REAIHARGGAINSNVFTRFLLAMFGVVTWRAVPVLPIEIVLLPFWSPFHLNKISYWARTT
MVPLMVLAALKPLAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFVLFRALDGILRVI
EPMFPKSLRQRAIDTALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKDENYPPRAVTR
RGIDKLLVFNGDEAYCQPCVSPVWDTTLTAHALLEAGGDIALPAAKQGLDWLIPKQELEV
KGDWAVKRPDVRPGGWAFQYNNAYYPDLDDTAVVVMSMDRMRREHGATGYDAAIDRGREW
IEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETEKTS
KHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVRHNDPMIRKAADWLAS
IQNKDGGWGEAAVSYRLDYKGWEASPSTASQTAWALLALMAAGEVDHPAVARGVEYLIAT
QNKKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>A0A0J1EEP6|squalene-hopene cyclase|EC 5.4.99.17|Rhodopirellula islandica|TrEMBL
MDRLRGELLAQRTEEGHWLGELSASALSTATAVSAMSAAVRSGELPDAEQAALLKQIQCG
RSWLAAQQNDDGGFGDTDRSHSNIATSYLVLAAWALSDQVIGEATDAGAVARLKGWIEAA
GELDGLRERYGKDKTFVVPILTNMAIAGLVPWKRVSALPFEAAVVPQSLYRFVGMPVVSY
AIPALVAIGQVKFLEGGGCLPPWSLVRRAAIEPSMKVLQSMQPSSGGYLEATPLTAFVVM
SLSASGRASHEVTQNGLRFLRESMLPDGSWPIDTNLANWVTSLATTALAMDPEDDRSWST
EALVQWQRGCQYQERHPFTGAAPGGWGWTDLTGSVPDADDTPGAIISLRMQATTKPSLLG
GDDSQPWPASQACDRGVDWLLGLQNRDGGWPTFCRGWGKLPFDRSSNDLTAHALRAIACL
PQRDSAKREPAIRRGLKFLRKNQQSDGSWLPLWFGNQDRAEEDNPVYGTSRVLVDASPEL
GHDAILRGLGYLIENQNGDGGWGGGPSVRETFALPEGSISTVEETALAVEALVSWWARIP
GDEGGQAGPNDILSGSLWDPSMRSSLRAAILSGTRWLIDAVQHERHQVAWPIGFYFAKLW
YYERLYPLVFTTAALGRVMQRDELLR
>K9V4Q0|squalene-hopene cyclase|EC 5.4.99.17|Calothrix sp. PCC 6303|TrEMBL
MQIQDRESNHQTPLQSESQLALRLSQSIASSQNYLLSRQYGDGFWWSKLESNVTITAEAV
LLHKIWGTDTSRPLNKIEAYLRSQQREHGGWELFYGDGGEISTSVEAYMALKLLGVTADD
AAMIRARDFILQHGGISKTRIFTKFHLALIGCYSWRGVPSLPPWVMLLPDNPWFSIYELS
SWARSSTVPLLIVFDKKPVYVTNPGITLDELYTEGIENVKYEIPKNYDWTDVFLGLDQVF
KFAESWNLVPLRKAGIEAAEKWILERQEATGDWAGIIPPMLNSLLALRSLGYDVNDPIVQ
RGLTAIDNFAIETDSSYCVQPCVSPVWDTAWVMRSLVASGVPSDHPAIVKAGEWLLQKQI
LDYGDWAVKNRHGKPGAWAFEFENRFYPDVDDTAVVVMALDVAKLPNENLKTAAIERALD
WVASMQCEAGGWAAFDLNNNQDWLNLLPYADLKAMIDPNTADVTARVIEMLGACHLSIPH
PNLERALEYLIKEQESEGCWFGRWGVNYIYGTSGVIAALALVNPHKHQANIQRGATWLIQ
CQNPDGGWGETCRSYNDASLKGKGNSTASQTAWAILGLIAADEVITEDWMKVAIERGINY
LLDTQQEDGSWYESEFTGTGFPCHFYLKYHMYQQYFPLLALGRYTADLREIKSTEKF
>A0A5P8KG17|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces phaeolivaceus|TrEMBL
MTATTDGSTGALPPRAPSASDTDHDSAVAVGVQDAAAHAMGRATDFLLSRQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDEKTTRAAALFIRGEQRPDGTWATFYGGPPDLSATVEAY
VALRLAGDGPEEPHMARASAWVRERGGIAAARVFTRIWLALFGWWKWDDLPEMPPEIVWF
PKWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPGRPNPPRPLDPLGSW
EGAFQRLDKLLHGYHKVALKRLRKAAMNSAARWIVERQENDGCWGGIQPPAVYSIIALHL
LGYDLRHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLAVIALADAGVPADHPQL
VRAADWMLGEEIVRPGDWSVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVAHHDP
ERVDRAVRRGVRWTVGMQSRNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLSHDPRTRRGIEWLLAEQEPNGAWFGRWGVNYVYGTGSVVPALVTAGLPAAHP
AIRRAVAWLETVQNDDGGWGEDLRSYPDPAEWGGKGASTASQTAWALLALLAAGERDAKA
TERGVEWLARTQRADGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPPVLT
ARGR
>A0A8G0XD51|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. MG28|TrEMBL
MTATTDGSTGALPPRAPSASDTVHDAPPTAGVQDAAAHAVRRATDFLLSRQDAQGWWKGD
LETNVTMDAEDLLLRQFLGIRDEKTTRAAALFIRGEQRPDGTWATFYGGPPDLSATVEAY
VALRLAGDDPGAPHMARASAWVRERGGIAAARVFTRIWLALFGWWKWDDLPEMPPEIIWF
PKWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPGRPNPPKAPDPLTSW
EGAFQRIDRLLHGYHKVALKRLRKAAMSSAARWIIERQENDGCWGGIQPPAVYSLIALHL
LGYDLRHPVMRAGLESLDRFALWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQL
VKAADWMLGEEIVRPGDWAVKRPHLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVAHHDP
ERVEKAVRRGVRWTVGMQSRNGAWGAFDVDNTSPFPGRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIEWLLAEQEPSGAWFGRWGVNYVYGTGSVVPALVTAGLPAAHP
AIRRAVAWLETVQNDDGGWGEDLRSYPDPAEWGGKGASTASQTAWALLALLAAGERDAKS
TERGVEWLAQTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPAVLK
AQGR
>A0A166R702|squalene-hopene cyclase|EC 5.4.99.17|Frankia sp. EI5c|TrEMBL
MSLTSDQSSAAPTAAHPNPRVPSPSAAPVEDAGTFEAGAAVLTDAPQPTSAATAQVDPAL
STLWRGRDHLLALQSEDGWWKGELETNVTMDAEDLMLRQFLGILTPETAAETGRWIRSQQ
LEDGGWATFYGGPSDISTTIEAYVALRLAGDDPQAPHMRSAAEWVRSAGGIAAARVFTRI
WLALFGEWSWDEVPVLPAELSFLPPWFPLNIYDFACWARQTVVALTIVGSLRPVRSLGFT
LDELRVPAPKPRRSPLRSWAGAFERLDVVLHRYEKRPFQPLRRLALRRAAEWVIARQEAD
GCWGGIQPPMVYSIMALHLMGYPLNHPVISMAFRALDRFTIREQTPEGMVRRIEACQSPV
WDTALAVVALSDAGVAGDHPAMVXAGRWLADEEIRVAGDWAVRRPALAPGGWXFEFDNDF
YPDVDDTAEVVIAIHRLLGDGHGPVDHTDGSGPGSAAAVAAEAAATAAPGAGTIAAADPE
LARQLRAAAERGVDWSVGMRSSNGAWGAFDADNVRTLVTKIPFCDFGEVVDPPSADVTAH
MVEMLALLGRADHPVTQRAVRWLLDNQEAGGSWFGRWGVNHVYGTGAVVPALISAGVSPS
HPAIVAALHWLVDHQTPDGGWGEDLRSYRDDSWIGRGEATASQTAWALLALLAAEPERGS
VEWEAIERGVRWLCDTQRADGTWDEPQFTGTGFPWDFSINYHLYRLVFPVTALGRYASLT
GRLTP
>E6Q8R2|squalene-hopene cyclase|EC 5.4.99.17|mine drainage metagenome|TrEMBL
MNRMLQPLHSGAGIFRSSLDRVIAQARQALGGRQAEDGHWCFEFEADCTIPAEYILMQHY
MDERDEALEARIAVYLRDKQADHGGWPLYYGGHFDLSASVKVYYALKLAGDDPELPHMRR
AREAILAHGGAERSNVFTRITLALFAQVPWRAVPFIPVEIMLLPRWFPFHIYKVASWSRT
VMVPLFILCSLKARAKNPLQVHIRELFRRPPDQITDYFSHARRGIVAYIFLSLDRFWRLM
EGWIPHGIRRRALKKAEAWFTARINGEDGLNGIFPAMVNAHEALELLGYPPEHDYRRQTG
AALRKLVVERANDAYCQPCVSPVWDTCLALHALLEQDGEVSPAVQNGIRWLKNRQIGAEP
GDWRESRPHLAGGGWAFQYANPYYPDLDDTAAVGWALARAGRAEDRDSIEKAANWLAGMQ
SRNGGFGAYDVDNTHYYLNEIPFADHKALLDPPTADVTGRVVAFLAHLARPRDRDVLRRA
VAYLLREQESSGAWFGRWGTNYIYGTWSVLMALAELDDPSLKPTMERAAYWLRAVQQSDG
GWGESNDSYSDPGLAGVGQTSTAAQTAWACLGLMAAGDRDSVALHRGIAWLQAHQERDGC
WQAPFFNAPGFPKVFYLIYHGYAFYFPLWALARYRNLGCMAHE
>A0A238H1K2|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia singularis|TrEMBL
MNDMTDMQTLDASDASVDTHAASATSAAAALDAAVARATDALLCAQNPDGHWVYELEADS
TIPAEYVLLVHYLGETPNIELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALK
VIGDDENAEHMQRARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEVMLLPQWF
PFHLSKVSYWARTVIVPLLVLNAKRPVAKNPRGVRIDELFKSPPVNTGLLPKQPHQSTGW
FMFFRAVDGMLRLVDGLLPSYSRERAINRAVAFVDERLNGEDGLGAIYPAMANAVMMYAA
LGLPEDHPNRAIARRSIEKLLVVGDDEAYCQPCLSPVWDTSLAAHALIETGDARAIDAAA
RGLDWLRPLQILDVRGDWIVRRPNVRPGGWAFQYANPHYPDVDDTAVVAMAMDRAAKERG
AQGQAQAAQPHAYRESIARAREWVVGMQSSDGGWGAFEPENTHHYLNNIPFSDHGALLDP
PTADVSGRCLSMLAQLGETPAASEPARRALDYLLNEQEADGSWYGRWGMNYIYGTWSALC
ALNAAGLGHDDPRVKRGAQWLLSVQNPDGGWGEDGDSYKLDYRGYERAPSTSSQTAWALL
GLMAAGEVNHPAVARGIDYLLGTQCEHGLWDEARFTATGFPRVFYLRYHGYRKFFPLWAL
ARYRNLKRANTTRVTVGM
>A0A8J7DDH5|squalene-hopene cyclase|EC 5.4.99.17|Romeria aff. gracilis LEGE 07310|TrEMBL
MQTPQTDQLIGLEQSIAAAQRYLLSIQKPDGYWWADLESNVTITAEIILLHKVWGTDHER
PLKKAERYLRSRQCDHGGWELFYNDGGDLSTSVEAYMALRLLGIPASDGALIKAKKFILS
RGGISQCRIFTKLHLALIGCYQWQGLPSLPAWVMLLEPPFPVSIYELSSWARGSTVPLLI
VFDQKPVYLVEPAFRLNELYAEGIENVRWEIPERGDWSDAFLWLDKAFKLAEAFNAVPFR
EAGLRQAEKWVIERQEASGDWGGIIPAMLNSMLALRALGYDANDPVVQRGLRAIDRFAVE
TEETYWVQACISPVWDTALALRALTDSGLAADHPALVQAGEWLLEKQILAYGDWSVKNPQ
GRPGGWAFEFENRFYPDVDDTAVVAMALQDITLPNEALKQSAIARAVRWIATMQCQTGGW
AAFDIDNNQDWLNAIPYGDLKAMIDPSTADITARVLEMHGRLSDDATLAVSYADTLTAQR
LARGLSYLMREQEPDGSWFGRWGVNYIYGTSGALSALALIAPERCQPQIERGVAWLVQCQ
NADGGWGETCRSYDDPSLKGQGPSTASQTAWALLGLIDAAFYPDSAAKSAVHSGIQYLLR
TQHEDGTWQESEFTGTGFPGHFYIRYHLYYQHFPLMALGRYRQQL
>A0A4Y8MRG6|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia dipogonis|TrEMBL
MNDLSQAQPLDAVLPDFADAAPSAPAPAIMGEAPTASLDAAITRATDAILAAQKPDGHWV
YELEADATIPAEYVLLVHYLGETPNLELEQKIARYLRRIQLPDGGWPLFTDGALDISASV
KAYFALKMIGDPADAEHMVRAREAILAHGGAETVNVFTRILLALFGVVSWRAVPMMPVEI
MLLPVWFPFHLSKVSYWARTVIVPLLVLNAKRPVARNPRRVRIDELFRGAPVNTGPRDRA
PHQHAGWFRFFSGVDVLLRAVDGLFPKATRERAVRQAVAFVDERLNGEDGLGAIFPAMAN
SVMMYDVLGYPADHPNRAIARQSIDKLLVIKDDEAYCQPCLSPVWDTSLAAHALLETGEA
HAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYNNAHYPDVDDTAVVAMAMQ
RSATVTQSDVDRDAIARAREWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPT
ADVSGRCLSMLAQLGELPQNSEPAQRAFDYMLKEQESDGSWYGRWGLNYIYGTWTALCSL
NAAGLPHDDPRMKRAAQWLLSIQNEDGGWGEGGESYKLDYHGYERAPSTASQTAWALMGL
MAAGEVNHEAVARGVAYLEREQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALAR
FRHLKRNGLTRVAVGM
>A0A7W1MQ77|squalene-hopene cyclase|EC 5.4.99.17|Chthoniobacterales bacterium|TrEMBL
MANPSANIIALPRVRPQESAPRLTTNDELAEAIALAQQNLLRQQKPDGHWVGELMVDSTL
CSDYVLFMHWLGEVDETLQRRCVKHILKRQLPDGGWNIYYGGPSEINACVKAYFALKLAG
HSPDAPFMQEARANIMRLGGIPRMNTYSKLYLALLGQFPWKYLPVIPVEMVLLPNWCFFN
IYKMSSWSRAMLIPLAIINHFKPTRDLLESKHLHELYPVGTEDNDFTLRRDQRSLTWRNF
FLRADRALKWLEPVHVRALRQRALEEAERWMVERIGEGSDGLAAVFPAMLNSLVALRALD
YPKEHPLYRKALRDFEGLFVDDPEDFRIQPCLSPVWDTAINIIALAESGFPAQHPALQKA
AQWLVDREVRVRCDWTANNSHSEASGWAFEYNNVFYPDTDDTAMVLMALRLVRPNEQPEL
AALFKRALDWQLSFQCADGGWAAFDKDVTRHWLEDMPFADHNAILDPTCSDLTARTLELL
GYIGFNPGRPLVRKAIRYLRETQEDDGSWYGRWGVNYIYGTWQVLRGLCAIGEDMTEDWI
LRGRDWLESCQNDDGGWGETCASYENPDLKGKGSSTASQTAWAIMGICACGDLDRLSVQR
GLRYLLATQREDGAWDEPEITGTGFPRVFYLKYDMYRQNFPLLALATYVNYRSGIGHYQS
FYRWAGT
>A0A850EPC1|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus agri|TrEMBL
MSDVLSAVDKEIDRMTSFLLQQQRQDGSWHYCFENGIVIDAYVIILFRILNVQNEKLIRQ
LYDRILNEQQPGGFWRLYPDEEDGNLSATVEAYYALLYSGYSKITDEPIQRAKRYIQSKG
GLAKVTSILTKAILAATGQAKWPLSISLIPLEVLMFPNYFPINYYEFSGYSRVHLTPMLI
MADRRFSITTADAPELSDLMDTRVDAEEPISREYQEMQKDIHSGLSRLIGTPRSIHEAAR
TKAEQFMLQRIESDGTLYSYATSTILMIFALLALKYDQQHPLITEAITGLTAMQYRSPGK
TTMQNSPSTVWDTALISYALQESRIGDDHKAITQAASYLLPRQHHKLGDWSIHNHSIEPG
GWGFSESNTINPDVDDTTAALRAIHSLSRTSGPYQESWNRGLNWVLSMQNKDGGWPAFEK
NTNKEMLTWLAIDGAKSAATDPSEADLTGRTLEYLGNFAGLDMRYEFIKRGSKWLIQNQE
KDGSWYGRWGVCYIYGTWAALTGLVAVGVPTSHDSVQKGAQWLLSIQNPDGGWGESCHSD
RLLHYVPLRESTPSQTAWALDALIATQPKATPAINQGIRRLITFMHEDDWKTTYPTGAGL
PGNFYIHYHSYRYIWPLLALSHYRKKYGDC
>S6CZB3|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter pasteurianus 386B|TrEMBL
MAADGSALSESRLSSEALDRAVLSAHTALSQAQQDDGHWVYELEADATIPAEYILLEHFM
DRIDDALEQKIAIYLRRIQSEEHGGWPLYHNGKFDLSATVKAYFALKAVGDDINAPHMQR
AREAILDHGGAERSNVFTRSQLALFGEVPWRATPVMPVELMLLPAKAFFSVWNMSYWSRT
VIAPLLVLAALRPVAANPRQVHVRELFVTPPEKVQDWIRGPYRSAWGYVFKGLDSVLRPV
VPFIPEKTHKKAIQAALDFIEPRLNGKDGLGAIYPAMANVVMMYRAMGVPDEDPRAKTAW
EAVQALIVEKDDEAYCQPCVSPIWDTGLSGHAMIEAASGPNGIAPEKTVAELKKASAWLR
SKQILNVKGDWAVRNPNLAPGGWAFQYGNDYYPDVDDTAVVGMLLHREGDPTNAEAIERA
RTWIVGMQSTDGGWGAFDIDNNKDVLNHIPFADHGALLDPPTADVTARCISFLAQLRNPE
DEPVIQRGLEYLRKEQEKDGSWFGRWGTNYIYGTWSALCALNAAGVSHDDPAVVKAVEWL
RSVQRADGGWGEGCESYEGGPHGTYGESLPSQTAWAVLGLMAAGRRDDPAVTRGIAWLAD
QQDANGEWHEDPYNAVGFPKVFYLRYHGYKQFFPLMALARYRNLESSNTRRVSFGF
>A0A800DH62|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
MKGYKLRRRVPQVADKIAATTLPLNIDKQALEQAIKGLQDYLLRIQSQEGYWVGELEADV
TVTAGYIPLMYFMTGKVDPIKQQKVINYARSKQRADGSWGTYYGGPGDLSVTIQAYFALK
LAGVSAEEPFMRRARHFILSHGGITRSNTLTKVWLALFGQFDWQGTPSMPPEIILLPNWF
YLNIYEFASWSRATIVALMVVLTEKPTCHVPEHARVSELYVEPEGNRDYSLGKLEKGFSW
RNFFLLLDRFFKTWEKLPFRPGRKLALRKAEKWIVDHQEADGSWGGIMLPWVYSLFALKS
LGYPLDHPVIAKGLKGLESFVVEDNSTLRLQPATSPVWDTAWAMIALSESGLSPSCPALI
KAAYWLLKEEIRTSGDWQVKNRKTEPGCWAFEFENDLYPDIDDTAVVPRALLKVKLPQTD
EDRKTDAIKRGMRWVISMQSRNGGWAAFDRNNNKRFLLHIPFADFMTPLDPTSPDVTAHA
VELLGELNGDSFSLERALTYLKNCQESDGAWYGRWGVNYIYGTGLVLAALQAAGEDMKQS
YVRRAVSWLEACQNSDGGWGETCHTYEDPLCRGKGPSTASQTAWALLGLIAAGEHAGNAV
RKGINYLINTQKEDGTWQEDAYTGTGFPKAFYLRYDLYRVYFPLIALARYKALLEVESNE
R
>A0A4V4RB33|squalene-hopene cyclase|EC 5.4.99.17|Marinifilum sp. JC120|TrEMBL
MNKKTAMKINKKAKNHVVSLLRPKDALNRVMKRFRSLQSPEGYWVFALEADVTIPSEYIM
FNRFLGRKMDKGLAERLGNYIRAKQMPDGGWPLHDNDGPVNISASVKAYMALKILGDNKD
AEHMVRARQIILAKGGAETSNVFTRICLATFGQIPWHCPPAMPIEIVLLPKWFFFHLDKV
SYWSRSVIYPLLIIYAKQPVCRLRPEEAVPELFCKPAEEHIHIDKFRDKGWRKNLFILLD
RVLKRTMHLVPKSINKKALNFAEKWTREHMAGRGGIGAIFPAMANAVTAMHLLRYDESDP
DFARGMQSVDDLMVDKFHVPEKSPWEHTVITGGAELSAAPELDLSPNHGTAENLEQAMCQ
PCNSPIWDTCLALSAMMEAGEDHDSKCTQQSLKWLWDQQIFFRGDWISKAPKLEGGGWAF
QFENTFYPDLDDTAMVLMAMCRAGVLDQPEHNENFVKGVNWLIGMQSSNGGWAAFDIDNC
AEYLNDIPFADHGALLDPPTSDLTARVIELLGVIGYDKSFRPIKDGIEFLKKEQEDDGSW
FGRWGVNYIYGTWSVLCGLRQAGEDMNSSYVCKAVEWFENHQNKDGGWGESCLSYNDKNY
AGLGDSTASQTSWALLGLMAAGRVNSKAVSRGVRYLLDTQKEDGSWDETLYTGTGFPRVF
YLRYHGYSQYFPMWALGVYQRFSAEEDTKQIMMRRTSPLDLGRKW
>A0A1W1I4R3|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira japonica|TrEMBL
MRFPDTITMSILRTLFDRLSDSLFISVPEKMGLARDLASAPPLRLVSDKSMPTPATDTAF
GRRTAGQTGSPVDTLDESIKRSQSWFLSRQHQSEGYWVAELEADTTLTAEYLMLRRFLDR
VDPERERKAVLYLRSAQLPDGGWPIYRGGPSEISASVKAYFALKISGVSADEPYMLRARD
RILAMGGVVQANVFTKITLALFEQYDWQGVPSMPPEIMLLPKRFYFSIYAISYWSRAVLI
PLLIVFANQPVCRLPKEQGIDELFVTPRTTIRYRQFPPFNKDQGWFTPHNVFVVLDAVLK
LYDRMPLAWVREKSLHRAASWMLEHMAGSGGLGAIYPAMANSVVALRCLGYQVDDPLVQK
ALREIEELEIHDTVTVEDQLVEAMHLQPCHSPIWDTALLMNALIEGGMAPDHLPLQRAAR
YLVSRQTKTVGDWKFSSHQAEPGGWYFQHENELYPDVDDSAVVLMALSKVRIPEAAALQE
SIKRGASWVLAMQGSDGGWGAYDKDNNRIVFNYIPFADHHALLDPSTSDLTGRCLEMLGA
LGYDQSHPAVAPALAFLKREQEHDGSWYGRWGVNYIYGTWSVLAGLRAIGEDLSQPYIRR
AVAWLESRQNPDGGWGESCLSYAEDESIGRGDSTPSQTAWALMGLMSAGMTDSFSVARGI
QYLLRHQSKDGSWEEACHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRTRGKMRADEV
RQHVLSHGSYRSPM
>A0A7Y9TGW6|squalene-hopene cyclase|EC 5.4.99.17|Granulicella arctica|TrEMBL
MSTLPRNPQTATKSAQPRYGRMDLGLEHVASGIARAKDWLLGKQHPDGYWCGELEADVML
EADYIFMHTLLGTGDAGKMQRALNEILRHQNEDGGWSQFPGGPSNINYGVKSYLALKLMG
WSAEHPLLVKAREWILANGGVVECNTFTKIYLCALGQYEYDAVPAVPPEIVLFPNWFYFN
IYEISSWSRGILVPLSIIYANKPFKKIAPEQGIDELFVGGRANANLHLRWDKKRLFGWRN
FFLALDRLMHWAERIHIRPLRKIAIKKAEKWMLARFEKSDGLGAIYPAMLNSIVAMRVLG
YSLDDPQMIRAMDEFEKLGIDCPEGEPEYPTPTFRMQPCFPPVWDTAQVVSALGEAGLSK
TDPRLLKAADWLLSKEVRHKGDWAEKVKNVEPGGWYFEFNNEFYPDVDDTGEVLLALNCV
DNPRERYQHEVCQRALNWIWAMQCKNGGWAAFDKDNTKTIFQYIPFADHNAMLDPPTVDI
TGRMLEMLAQYGFTRDDKRVEKAIQFVLKEQSPDGSWFGRWGVNYLYGTFLVLRGLEAIG
MWSHEPCILQATEWIRMMQNSDGGWGETCGTYDDELQKGIGPSTPSQTAWALLGLLAGGD
SRSDSVAKGVRWLIDRQHEDGSWDELVPGRNGESYYTGTGFPRVFYLGYHLYKQYFPLLA
LTTYKRAMERETA
>A0A4R0JNU5|squalene-hopene cyclase|EC 5.4.99.17|Kribbella capetownensis|TrEMBL
MTAERLAQDEKSDLRVENCLDAAVEYLRSLQHEDGWWKGDLATNVTMDAEDLMLRRFLGV
ATAQTDAETARWIRSQQRDDGTWATFPGGPGDLSTTVEAWVALRMAGDDPAEPHLAKAAE
FVRSAGGVEKARVFTHLWLALFGLWEWDDCPDLPPELIFLPGWAPLNVYNWACWARQTIV
PLTIVSALRPVRPVDFGIDQLRAGTPAARKAPPWSLDGGFQLLDVVLNAYTRWGPRGPLG
GIRRLAMRRSVEWIVARQEADGGWGGIQPPWVYSLIALHLMGYATDHPVMAAGLRGLEGF
TVHADTVGGPVRWLEACQSPVWDTGLVVGALLDAGVAPDDKAVLKATDWLLDEQIDAPGD
WQVRRPTLTTGGWAFEFANDGYPDTDDTAEIVLALRRVVHPEPQVLRAALDDAVEWTAGM
QSADGGWGAFDADNTDTTPLRLPFCDFGAVIDPPSADVTAHVVEMLAAEGKTGTDECRRG
VRWLLDSQESDGSWFGRWGTNHVYGTGAVVPALIAAGTSADDPVIRCAVRWLADHQNPDG
GWGEDLRSYVDPSWIGRGDSTPSQTAWALLALVAADERDETVRRGIGYLVDTQRPDGGWD
EHRYTGTGFPGDFYIGYHLYRLVFPIWALGRYLGRDRPHHEGAVSR
>A0A6H1KND2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. RPA4-2|TrEMBL
MTATTDGSTGALPPRAAAASEIQPETTPVAAGTVETRDVAEHAIQRATGYLLSRQDAEGW
WKGDLETNVTMDAEDLLLRQFLGILDETTAQAAGLFIRGEQREDGAWATFYNGPGDLSAT
VEAYVALRLAGDAPDAPHMAKAAAWVRERGGIVSARVFTRIWLALFGWWKWDDLPELPPE
LIYFPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPGNPNPVRPTAP
VASWNGVFQRLDKALHQYRKVAPGPLRRAAMNAAARWIIERQENDGCWGGIQPPAVYSVI
ALHLLGYDLDHPVMRAGLESLDRFTVWREDGARMIEACQSPVWDTCLATIALADAGLPAD
HPQLVKAVDWMLGEEIVRPGDWSVKRPHLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVR
HHDPERVEKAIGRGVRWNLGMQSKDGGWGAFDVDNTSSFPNRLPFCDFGEVIDPPSADVT
AHVVEMLAVEGLSHDPRTRRGIEWLLAEQEPNGSWFGRWGVNYVYGTGSVVPALVAAGLP
ASHPAIRRAVGWLETVQNEDGGWGEDLRSYDDAAEWSGRGASTASQTGWALLALLAAGER
DSKAVERGVDWLAATQLPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEP
FAEVKGG
>A0A7Y2G3Y8|squalene-hopene cyclase|EC 5.4.99.17|Marinicaulis sp|TrEMBL
MDLKAVNTMFDDETQTGAANSNFGKQLSGSIDAAADWLAARQKPEGYWVGRLESNGCMEA
QWILALWFMGLEDHHLRPRLAESLRQTQREDGSWEIYHGAPAGDINTTVEAYAALRSVGA
PKNDPAMQRAYDWIMSKGGLKNIRVFTRYWLALIGEYPWERTPNLPPEVIYFPNWFPFSI
YNFAQWARATLMPIAVLSARRPSRALPQENRLDEFFPEGRNNFDYSYPEKPGADIIDSFF
VGVDRLLHWGQSAGIAPWRRGAVKRALEWIIEHQDADGVWGGIQPPWIYSMMALYNEGYA
LDHPNVAAALGALDDPRWRVDVGDATWIQASVSPVWDTLLTLLAYDDANQNDRHSEHVEK
AVDWILSQQVLRPGDWQVKVPNVEPGGWAFEYKNYFYPDTDDTAVALIVLSQFRDDPKWR
EKGIERAIQTGVNWLFGMQCKGGGWGAFDKDNDKTYLTRIPFCDFGEALDPPSVDVTAHI
VEAFGKLGFRMDHPQICRAIDYLQAEQEQNGAWFGRWGVNYVYGTGAVLPALEAIGEKMD
RPYIQKACDWLVAMQQDDGGWGESCASYMDPNMTGKGTTTASQTAWALMGLIAANRDADR
EAIERGIAFLMERQNDGTWDEPEYTGAGFPGYGVGATIKLGDPLLAERLKQGPELSRAFM
INYNLYRHYFPLMALGRWREKLG
>A0A6L3N085|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia stagnalis|TrEMBL
MNDLTDMPTLSAGTVPAELDTAVQRATDALLAAQQPDGHWVYELEADSTIPAEYILLVHY
LGETPNLELEQKIGRYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPIAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYDALGYAEDHPNRAI
ARESVEKLLVVHDDEAYCQPCLSPVWDTSLASHALLETGDPRAEDAVVRGLEWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANPHYPDVDDTAVVVMAMDRVEKLRHSDMYRDSIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETAA
NSEAARRSLDYMLKEQEPDGSWYGRWGMNFVYGTWTALCSLNAAGLGPEDPRMKRGAQWL
LSVQNKDGGWGEDGDSYKLDYRGYEQAPSTASQTAWALLGLMAAGEVNNPAVARGIDYLI
AEQQEHGLWDEARFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNATRVTVGM
>A0A8H1LJV8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces albus|TrEMBL
MTATTDGSAGPGVSGTKNLTSDTLAPAAGGRESTVALAERTAARAVDHLLARQDEAGWWK
GDLDTNVTMDAEDLLLREFLGIRDEKTSAAAARWIRSQQREDGTWATFYGGPGELSTTIE
AYVALKLAGDDPEAPHMARAAAWIREQGGIVRSRVFTRIWLALFGWWRWEDLPEMPPEII
WFPKWFPLNIYDFGCWARQTIVPLTIVCAYRPVHPAPFRLDELHVDPARPNPPAAKAPLT
SWDGAFQRIDRALHAYRKVGSRRLRRAAVKEASRWIIERQENDGCWGGIQPPAVYSLIAL
RLLGYDLDHPVLKAGLESLDRFAVWHDEQTRMIEACQSPVWDTCLTAIALADAGLPRDHP
ALVKAADWMLGEQIVRPGDWSVRRPQLTPGGWAFEFHNDNYPDIDDTAEVALALRRIGHP
DSERVNRAIARAVRWNLGMQSRDGAWGAFDVDNTSKFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAAEGKQDDPRTRKAIAWLLSEQESNGSWFGRWGVNYLYGTGSVVPALVAAGLPTS
HPAIRRAVGWLESVQNDDGGWGEDLRSYIDSEWIANGTSTASQTGWALMALLAAGEQDSK
AVERGVTWLAETQREDGYWDEPYFTGTGFPWDFSINYHLYRMVFPLTALGRYLHGDGLAR
RTGRDA
>A0A3Q8WRG5|squalene-hopene cyclase|EC 5.4.99.17|Kitasatospora albolonga|TrEMBL
VTATADGRLDPEYDPEPAAVGERPPVTDRLTGRQTTVATAPAPGAGRRQAEGPERSGPLD
PAQALARATAELLSRQSPDGWWKGDLETNVTMDAEDLLLRQFLGIREPEQTAATAAWIRS
QQREDGTWSTFYGGPPELSTTVEAYVALKLAGDDPGAPHMAAAARYVRERGGIAASRVFT
RIWLALFGWWPWERLPEMPPEIIFLPRWLPLNIYAFGCWARQTIVPLTVVSAHRPVRPAP
FDLTELHTDPADPYPLRPLAPPTGWDGVFERLDLVLHAYHKRALRPLRRAALAQAGRWIV
ERQEADGCWGGIQPPAVYSLIALHLLGYDLEHPVMRAGLAAFDRFTVHTEDGRRWLEACQ
SPVWDTCLATIALRDAGLPADHPALVSAADWMLAEEIRRPGDWSVQRPRLAPGGWAFEFE
NDNYPDIDDTAEVVLALKRVAHPDRARIDGAVRRGVEWNLGMQSRNGAWGAFDVDNTSTL
PNKLPFCDFGEVVDPPSADVTAHVVEMLAETGLAGDRRTRRGIDWLLKNQEPDGSWFGRW
GTNYIYGTGSVLPALVAAGIPGSHPAVRRAVDWLADRQNPDGGWGEDMRSYEDPVRWSGR
GDSTASQTAWALMALLAAGEGPDGARSEVVERGVQWLCRTQLPSGSWDEPQFTGTGFPWD
FSINYHLYRLVFPVTALGRYLHGSPLTGGGA
>A0A7M2WYW5|squalene-hopene cyclase|EC 5.4.99.17|Phycisphaerales bacterium|TrEMBL
MLTADATAAEPLSDRSLETASTGTLSSSTLDRAIEAACEALVARQDPAGFWCAELQGDSI
LESEYLLLMWILGREAEPDLPLIANYLRKIQNPDGGWSLYPGGPADISGTVKGYFALKLM
GDSPDAPHMRRARELILSLGGAEKCNTFTRFYFACLGQISFDACPSIPPEIVFLPKWFYF
NLYHVSAWTRTMILPLGLVTTFRRARKLKPEQGISELYLDRQAANRLSLKPLSGLPKTWQ
EIFLRIDQLLKVYDKTPNDTLRQKAIKKAEEWILDHLSGSEGLGAIFPPMVYLLIVFQLL
GYPENHPRVVKAHKELRDFFIQDGDEIRIQPCLSPMWDTGIALNALAEAGLSPGDDVARR
STQWLLAKECRVASDWQKNCRPVEASGWFFEFENAHYPDTDDTAMVCTSLSRVGGPDAQS
AVKRGVNWLLAMQNDDGGWAAFDRTTDRPLLEKIPFADHNAMQDPSCPDITGRVIEGLGR
CGMRVGHPAIDRAVQYIRKQADADGAWWGRWGVNYVYGTWQVLTGLKAVGQDMSESWTRK
AADWLLSVQKPDGSFGETCASYDDARLKGQGDSTASQTAWGAMGLMAVHGASHPAIEKAI
RWLIETQTHEGSWEETNYTGTGFPRVFYLKYHYYRLYFPLTALARYRRLRS
>A0A7Y3K012|squalene-hopene cyclase|EC 5.4.99.17|Phycisphaerales bacterium|TrEMBL
MDRIDVYRAAVAPSFADVRFPDICPRPEPMPSMLSDEKSTAHALQKAQTALLRQQHTKGY
WVGELQGDSILESEYILLKFILEQESDPDLPLIANYLRSLQQADGGWTLFPGGPSDLAGT
VKAYFALKLLGDDVDAPHMRVARDVVRKLGGAELCNSFTRFYLAALGQISYDACPSIPPE
IILIPKWIYFNLYAVSAWSRTMILPLAIVSAFRPVRKLSAEQGISELFNDIAAANSAAGK
LKGLPRSWREMFLLIDLSLKRYEKTAVTPLRPRAIREAEKWLLDHLEGSEGLGAIFPPMV
YILIVLRILGYSDNHPVVQKAHRDLKDLFIRDGDSIRIQPCWSPVWDTGIALHALAEAQI
SPDDPVAQKASQWLLAKECRVGSDWTKNCPDVEPSGWFFEFENPHYPDVDDTAMVAMALK
RAGGPTAAAAVKRGVNWLLAMQNDDGGWAAFDRTRSRPILEHVPFADHNAIQDPSCPDIA
GRTLECLGHNGLKYDHPAVRKAVSFLKETQEKEGCWFGRWGVNYIYGTWQVLTGLRSVGE
PMDQRFIRRAADWLRSCQKPDGSWGESCQSYDNPELKGRGPSTPSQTAWGAMGLMAVAGA
QDPAVVRAINWLVENQTSEGDWDEPWFTGTGFPRVFYLKYHLYRLYFPLTALARYQRLQA
AS
>A0A7W4PBE6|squalene-hopene cyclase|EC 5.4.99.17|Gluconacetobacter tumulicola|TrEMBL
MMVNATDTLERPSADVADLAVPMIEIDQAVDAGHAALGRRQNDDGHWVFELEADATIPAE
YVLLEHYLDRIEPALEARIGVYLRRIQGDHGGWPLYHGGRFDLSASVKAYFALKAIGDDI
NAPHMARARAAILDHGGAERSNVFTRFQLALFGEVPWHATPAMPVELMLLPRRAFFSVWN
MSYWSRTVIAPLLVLAALRPRAINPRDVHVPELFVTPPAQVRDWIRGPYRSPLGRVFKYV
DKVIRPGERLIPEATRRRAIKAAVDFIEPRLNGVDGLGAIYPAMANSVMMYRALGVPDSD
PRAATAWESVRRLLVEHGDEAYCQPCVSPIWDTGLAGHAMIEAASGPEGICPEETKKKLA
AAACWLLDRQILNVKGDWAINCPDVAPGGWAFQYNNDYYPDVDDTAVVGMLLHREGDPAH
HEAIERARQWIIGMQSTNGGWGAFDIDNNMEFLNHIPFADHGALLDPPTADVTARCVSFL
AQLGRPEDRPVIERGIAYLRTDQEAEGCWFGRWGTNYIYGTWSVLCALNVAGMSHDDPAI
VRAVDWLRSVQREDGGWGEDCATYEGATAGIYTESLPSQTAWATLGLMAAGLRDDPAVAQ
GMAYLARTQKEDGEWDEDPYNAVGFPKVFYLRYHGYRQFFPLMALARYRNLESSNTRRVA
FGF
>A0A3A9ZPB7|squalene-hopene cyclase|EC 5.4.99.17|Micromonospora costi|TrEMBL
MTELLSPKTTTTGANRPAVADPLDGARDALHRAREHLLGLQDDAGWWKGDLATNVTMDAE
DLMLRQFLGIRTEEQTAESARWIRSQQRPDGSWALFHGGPGDLSTTIEAYVALRLAGDTV
EAPHMAAAAAFVRANGGLTASRVFTRFWLALFGHWPWSRLPAVPPELVLLPSWVPFNVYD
FACWARQTIVPLSIVRALRPVRSLGFGVDELRTAAPPPRPPRLASRPGLLYRADRLASGY
ERIARGPVRRHALRRAAEWIVARQEADGSWGGIQPPWVYSLMALHLLGYPLDHPVLRAGL
AGLDRFTVRTETPDGPARWLEACQSPVWDTALAVTALSDAGLPPAHPALERAGRWLRDEE
IRVRGDWAVRRPRTPAGGWAFEFENDGYADTDDTAEVIMALRRTTVPVEAPVLRATRWLL
GMQSRDGGWAAFDADNTRAILGDLPFCDFGEVIDPPSADVTAHVVEALAAENFAGTMPVR
RGVHWLLRHQEPDGSWFGRWGANHVYGTGAVVPALVAAGVPRTHPAIRRAVDWLRAHQNA
DGGWGEDLRSYRDRSWIGRGESTASQTAWALLALHAAGQGTAEPALRGVRWLVDTQRPDG
GWDEPQYTGTGFPGDFYINYGLYRLVFPISALGRILGARAGDLEATVTR
>A0A8I1PG47|squalene-hopene cyclase|EC 5.4.99.17|Pseudonocardia sp|TrEMBL
MTLTAPELLATRTPRAALDAAVAFLRAGRHPDGWWQGELETNVTMDAEDLLLREFLGIRT
DTETAEAARWIRSRQRADGSWATFQDGPADLSTTIEAWVALRLAGDAPDAEHMLRAQKFV
VSQGGLERSRVFTRIWLALFGLWSWDELPDMPPELIFLPKWFPLNVYDWSCWARQTVVPL
TVVATLRPCRPLPFDVDELRTGAAAPPLGKPWSWAGAFQRLDKVLHAYSRRPLRGVRRLA
MRRAAEWVLARQEADGSWGGIQPPWVYSILALHLLGYPLDHPAVAAGLRGLDRFLIREQT
PDGVVRRLEACQSPVWDTCLAVTALLDAGVPADDPDVLAAAEWLLAEEITGVRGDWAVRR
PEIPTGGWAFEFDNDGYPDTDDTAEVVLALRRVAHPVPERVRAAVDRGVAWTVGMQSRDG
GWGAFDADNTRELVTKLPFCDFGAVIDPPSADVTAHVVEMMAAEGLAHTTECRRGVEWLL
AAQERDGSWFGRWGANHVYGTGGVVPALVAGGIDPDTPPIRRAVAWLERHQNTDGGWGED
LRSYEDPAWIGKGASTASQTAWALLALLAAGEDGEVVERGVRYLVDTQLPDGSWEETLYT
GTGFPGAFYIRYHLYRMVFPVSALGRYVNGQPS
>A0A6G9FBP7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. Tu 2975|TrEMBL
MRYPTLPGTVTETKIPTRRLTTRQLAERARMRAVGHLLSRQDAQGWWKGTFEGNVTGDAE
DLLLRQFLGIGDEENTHAAGLYIRGEQREDGTWSTFYGGPGDLSTSIEAYVALRLAGDAP
DEPHMAKAAAWIRAHGGIAASRVFTRIWLALFGWWKWEDLPALPPELVFLPKWFPLNIHH
FASWSRQTIVSLTVVCAERPVRPAPFTLGELHPESETPPPSAPHVPAGHWTRFFTCLDKA
LHAYHKVAPRRLRRAAMSNVACWIKERQESDGCWGGLQVDATYALIALHLLGYRLEHPVM
RAGLASLDAFAVRRQDGARVIEVSQSPVWDTSLAVNALTDAGVRCDHPALVRAGDWMLGK
QHARPGDWAVRRPGLDPGGWAFQFHNENNPDLDDTAEVILALRRLQHPDPVRVDAAIERG
VRWSLGMQSKNGGWAAFDVDNTSSLAGRLPFCDFGEVTDPPSADVTAHVVEMLACEGKLY
DPRTRRGIAWLLAEQEASGAWFGRWGVNYLYGTGAVVPALTAAGLPAAHPAIRRAVTWLR
SVQNDDGGWGEDVRSYRDERWAGQGTSTPSQTAWALLAVLAAGEGDSEAVERGVRWLVQA
QHENGTWEEPHFTGTGFPGDYSIRYHLYRQVFPLMALGRYLHQGTPGELRCKTTDVPHSP
EP
>A0A552PPC0|squalene-hopene cyclase|EC 5.4.99.17|Microcystis panniformis Mp_MB_F_20051200_S9|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYPDGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQEQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKSNNWSDVFLWLDGLFKWAEKTNLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALDYDVDDPIVARGLKAVDNFAIE
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKAVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYSDLKAMIDPNTADVTARVLEMLGTCDVKMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYHHQLQKGANWLSGCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWNE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYQALI
>A0A151AZC8|squalene-hopene cyclase|EC 5.4.99.17|Moorella mulderi DSM 14980|TrEMBL
MLKQKISGLALAFLILFLLIAGAVTPAWALTGRDSAGKSLNNAADYLLTREKARGILSPW
SYIALAASGRDLKGTLAGQACEKMLAAATASGEMNDYATLVLAVLAAGGNPYNYQGQNLI
KKIQDAQLASGKFADNIAHGGEQLVNAHIWAVLALHAAGADIPDKSKALSWLVARQHADG
SFYWDATDKETPDVDSTGMALMALGALGEKKDSPVVQKAVAYLEKAQKENGSFESWGAEN
PESCSMVIEGLIVVGIDPLQGNFNKAGGDVLTALLRFQLPDGSFEHLRGTGSNEMATSQA
LMALASIYFGQPFYARLATPPAATRYKARFIVGARSYTIFAGEKEEVKAMDAAPFIDNGR
TYVPVRYLAYALDVASDGISWDEKTAAVKLSKDGVTVTMVIGEETGYVNSQARSTGVAPL
LRDGRTYLPARFVAEAFGYQVDWDATSQTVSIKNSN
>A0A7Z9S2C4|squalene-hopene cyclase|EC 5.4.99.17|Rhodospirillales bacterium|TrEMBL
KLLVLRDDWGYCQPCLSPVWDTGLAAHAMLESGLTNDDPILAKANEWLLGRQIFEVQGDW
AANRGHVRPGGWAFQYWNDYYPDVDDTAVVVMALHRADPEKYREAIERGTEWIIGMQSIN
GGWGAFDADNNHFFLQNLPFADHGALLDPPTADVSARCLGMLAQLGYETDHPVMAKGLAF
LRSEQEKEGSWFGRWGNNYVYGTWSVLCAFNAAGENMQARHIRKAVDWLKYVQRPDGGWG
EDCSTYWQYRRDEVKTSTPSQTSWALMGLMAAGEVDSNSVARGVEYLLNAERDGGNWHEE
YFNAVGFPRIFYLRYHGYSAYFPLWTLSRYRSLKKTNSKFPKYGL
>A0A327MAS4|squalene-hopene cyclase|EC 5.4.99.17|Roseicella frigidaeris|TrEMBL
MFDLSIMQDLAAAAARPDFALAGGLTEGPDRTGLDAAIGRATDHLLRCQQADGHWVFELE
ADATIPAEYIMLRRFFGRRDPAREVRIGRYLRRVQAQEAATAGGGWPLFHGGPIDVSCSV
KAYFALRLIGDAPEAPHMARARAAILAAGGAERSNVFTRATLALFGEVPWHAVPVMPPEI
CLLPRWFPFHLSKVSYWARTVLVPLTVVMARRPVPLVPTGVSLRELFRTPPERVRRWPGG
AHAAEPWKTLFASLDWVLQRTQHHFPAGARARAEAKAEAFVTERLNGEDGLGAIYPAMAN
AIWMYHCLGVPEDDPRVVTAWSAVEKLVLDRKAEPATAGEDTGESREESYVQPCLSPIWD
TALVSHALLETGEARAEAAVARGLSWLLERQITDVAGDWAEARPGVPPGGWAFQYANPHY
PDVDDTAVVVLALDRAERQIGPAGGRVAKAVARATDWVVAMQSKGGGWGAFDADNTHHHL
NSIPFADHGALLDPPTSDVSGRCLAMLAQLGHGSDHPAVRSAIDYMLAEQEPDGSWYGRW
GVNYVYGTWSALTALNAAGLAPEHPAMQKAVAWLKARQNPDGGWGEDGFTYPRCGGTRAD
TDLAMGPSTASQTAWALLALMAAGAVDDPAVERGAQWLLRQQRADGAWPEEDYTGTGFPR
VFYLRYHGYARLFPLWALARLRNLRRGNSRQVVHGL
>A0A7W0DA90|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus sp. CGMCC 1.16610|TrEMBL
MPVWNEVDEEIRRMRASLEQWQQQDGSWRFCFENSLLTDAYMIIVLRTLEVPQEALIKQL
HDRIAAEQEPNGAWKVYQDEADGHLDTTVNAYFALLYSGYSQKTDEPMMKAARFITSKGG
IKQVKTFLTKVFLATAGQYPWPSSIMIPLEFLLLPLTSPVNFFDFSGFARVHFAPVLIMA
DLKFVRKNAVTPDLSDLTLPVRQEHESPRGFQELLKEVHTGIKQLTSLPQQLHKRAIRYA
ETYMLERIEADGTLYSYATCTLLMILSLLALGYDKNHPTITAALNGLYSMLWNINGKVHL
QNSPSTVWDTALLAAALQQAGTSPDHPSIAKAVHYLHGLQQSKLGDWKFHVAHPIAGGWG
FSESNTINPDVDDTTAALRAIHVTAQRNPKYQDVWNRGLNWVLSMQNKDGGWPAFERGIT
NKLLTLVPIDGASAAAIDPSTADLTGRTLEFLGATAGLDIRQTFVHRGADWLFSNQEADG
SWYGRWGVCYIYGTWAALTGLMAVRTKPDHPAVQKAVDWLLSIQNEDGGWGESCSSDSFK
HYVPLGASTPSQTAWALDALIAVCDEPLPAIRKGMRQLLLLLHKDDWTTRYPTGAGLPGS
FYSNYHSYRFIWPLFTLSNYQKKYEHL
>A0A7W8RND1|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia sp. Cpub6|TrEMBL
MNDLSHTQPLDAALPEAADAAPDLAEAAVVANAPAVADALATATPAPVQGASPLDASITR
ATDAILAAQQPDGHWVYELEADATIPAEYVLLVHYLGETPNLELEQKIARYLRRIQLPNG
GWPLFTDGALDISASVKAYFALKMIGDPVDAEHMVRARDAILAHGGAEHVNVFTRILLAL
FGVVSWRAVPMMPVEIMLLPVWFPFHLSKVSYWARTVIVPLLVLNAKRPLARNPRKVRID
ELFRGAPVNTGMNQRAPHQHAGWFGLFRCVDSVLRAVDGLLPKATRERAIRAALAFVDER
LNGEDGLGAIFPAMANLVMMYDVLGYPADHPHRAIARKSLDKLLVIKDDEAYCQPCLSPV
WDTSLAAHALLETGEARAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYNNA
HFPDVDDTAVVAMAMHRSAALTQSDVDREAIARAREWVVGMQSSDGGWGAFEPENTQYYL
NNIPFSDHGALLDPPTADVSGRCLSMFAQIGELPQSSEPARRAFAYMLQEQESDGSWYGR
WGLNYIYGTWTALCSLNAAGMPHDDPRMRRAVQWLVSIQNDDGGWGEGGESYKLDYRGYE
RAPSTASQTAWALLGLMAAGEVDHEAVARGIDYLQREQREHGLWDETRFTATGFPRVFYL
RYHGYRKFFPLWALARFRHLKRNGLTRVTVGM
>A0A2I2L051|squalene-hopene cyclase|EC 5.4.99.17|Frankia canadensis|TrEMBL
MALSGMADVEGRPESAGAGTDVTPDRADHAAAVDRDPASGPTRTLRRAATHLLARQAEAG
WWKFDLESNTTMDAEDLLLREYLGIRTAELTEASARFIRSRQLADGSWPQYHGGDGDLSV
TVESYIGLRLAGDDPADEHMSRAAAWVRERGGIPATRVFTRIWLALFGWWRWEDLPVLPP
ELMLLPRRVPLNIYSFSSWARQTVVALTVVSTFRPVRPAPFALDELHPAVAERSEPAAAR
RRTRSWSRPRAFGWREAFVAADAMLHRYHARPFWPLRRHAIRVAEQWIIARQEADGCFGG
IQPPAVYSIIALRLLGYDLDHPVISATLRALEDYSVELPDGARMVEASQSPVWDTALAVN
ALVEAGPAAGIEPDDPALVHAVDWLLGQEIRHRRGDWAVNHPDLPAGGWAFEFENDTYPD
TDDTAEVLLALRHVRHPAARDVAAATARGVTWLFGLQSSDGGWGAYDSDNTGTIHYMIPF
ADFGALTDPPSADVTAHVVELLAEVGLADDPRTRRGVDWLLRAQESDGSWFGRWGVNYVY
GTAAVLPALRAAELPATHPAIRSGVDWLLDHQNADGGWGEDLRSYDDPARWAGRGESTAS
QTAWAMLGLLAGEQRPAVARALERAARWLAQHQRPDGTWDEDQFTGTGFPGDFYLNYQGY
RLLWPVQALGRYVRELSASSPARSAAVAAIPGPRAVDRS
>A0A845ZRM6|squalene-hopene cyclase|EC 5.4.99.17|Moorena sp. SIO3E2|TrEMBL
MQTQDRIVESGVTGAIANSQSYLLAQQYPDGYWWAELESNVTITAEIVLLHKIWGTDKQR
PLHKAEAYLRSQQQKHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDSALVRARDFILR
RGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPEWFPFTIYEMSSWARGSTVPLLI
VFDQKPVFEIEPRINLDELYTEGADQVKFELPRNSDWTDLFVLLDDGFKLAEDWNLVPFR
KQGLAAAEKWVLERQEATGDWGGIIPAMLNSLLALRCLNYDLADPIVQRGLEAIDRFAIE
TPDSYRVQACVSPVWDTAWVLRAMVESGLEPDHPALVRGGEWLLQQQILDYGDWVVKNPQ
GKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPNQKLKQAAMARGLAWIASMQCNQGGW
AAFDINNNQHWLNSLPYADLKAMIDPNTADVTARVLEMLGSCNLSIESQKLENAIAFLIQ
EQEADGSWFGRWGVNYIYGTSSALSALSKIAPHTHQRSIERGAAWLVKCQNLNGGWGETC
LSYDDPTLKGLGISTASQTAWALIGLMAAGEATGNWAMDAIEMGVNYLVSTQQPDGSWDE
TEFTGTGFPSHFYLKYHFYQQYFPLLALGRYQISISS
>A0A0E3PCA1|squalene-hopene cyclase|EC 5.4.99.17|Methanosarcina siciliae HI350|TrEMBL
MTNEQVLNGRILSNRILNDRISDNRTLNDKISGNKIFDNRMLKAVELAIRKASNFIISNQ
SGEGYWLDFYIPGMGNSSQWVTAYIAYNLSRLPNTDESVQKAIVWLLHTKSSSGWGYHQN
CLHDADSTANVVRLLAYYFKKENLLTQENFAFYLHEFADLLASYQDKNTGGFLTYLPGSN
GRYHTMPDSAWCISEPSITAMAGNAFLNSGPERFEQEISNAREFLISRQNPAGYWDSYWW
DCRIYGTSLACSFLKQLGEIDPVKKAISWLESVFVPSKGWGNGYEADPYPFYTALSLSSL
LLFENNIHSREVKDSVLWLIGNQKEDGSWFSKPILRVPDPQVREPWAGSNRRKCEVVTDV
NLLFTTATVMGVLYDFLNLSGYYSCSASQE
>A0A844INW2|squalene-hopene cyclase|EC 5.4.99.17|Dolichospermum sp. UHCC 0260|TrEMBL
MQTQDRIKVKQVVDAIAASQKHLLSIQNPDGYWWAELESNVTITSEAVLLHKIWGTEKTR
PLHKVENYLRSQQREHGGWELFYGDGGDLNTTVEAYMALRLLGVPATDTALLKAKSLILA
KGGISKTRIFTKLHLALIGCYNWRGLPSLPPWVMLLPDNFFFNIYELSSWARSSTVPLLI
VFDRKPIFNIDQPINLDELYAEGVNNVCWELPKNGDWSDIFNILDDGFKLVESINFVPFR
NEGIKAAEKWILERQEVTGDWGGIIPAMLNSLLALKCLDYDANDPVIERGLKAVDNFAIE
TENSYCVQPCVSPVWDTAWAIRALIDSGFAPNDPAIVKAGAWLIEKQILDYGDWNVKNKQ
GKPGAWAFEFENRFYPDVDDSAVVVMALHQAKLPNEELKKQAINRALNWIATMQCKPGGW
AAFDIDNDQEWLNSVPYGDLKAMIDPNTADVTARVLEMLGACNLSIQPDNLEKSLDYLLK
AQEIEGCWFGRWGVNYIYGTSGVLSALALINPLKYARDINQGAAWLVKVQNSDGGWGETC
FSYNDPNLKGKGDSTASQTAWALIGLIAAGEATDKLAIDSIEKGINYLLETQKLDGTWDE
EYFTGTGFPCHFYLKYHLYQQYFPLMALGRYQAKCSS
>A0A1Y0V2K2|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter ascendens|TrEMBL
MAADGSAFSESRLSSEALDRAVLSAHTALSQAQKDDGHWVYELEADATIPAEYILLEHFM
DRIDDTLEQKIAIYLRRIQSEEHGGWPLYHNGKFDLSATVKAYFALKAVGDDINAPHMQR
AREAILDHGGAERSNVFTRSQLALFGEVPWRATPVMPVELMLLPAKAFFSVWNMSYWSRT
VIAPLLVLAALRPVAANPRQIHVRELFVTPPEKVQDWIRGPYRSAWGYVFKGLDSVLRPV
VPFIPEKTHKKAIKAALDFIEPRLNGKDGLGAIYPAMANVVMMYRAMGVPDEDPRAKTAW
EAVQALIVEKDDEAYCQPCVSPIWDTGLSGHAMIEAASGPNGIAPEKTVAELKKASAWLR
SKQILNVKGDWAVRNPNLAPGGWAFQYGNDYYPDVDDTAVVGMLLHREGDLANAEAIERA
RTWIVGMQSTDGGWGAFDIDNNKNVLNHIPFADHGALLDPPTADVTARCISFLAQLRNPE
DESVINRGLEYLRKEQEKDGSWFGRWGTNYIYGTWSALCALNAAGVSHDDPAVVKAVEWL
RSVQRADGGWGEGCESYEGGPHGTYDESLPSQTAWAVLGLMAAGRRDDPAVTRGITWLAD
QQDANGEWHEDPYNAVGFPKVFYLRYHGYKQFFPLMALARYRNLESSNTRRVSFGF
>A0A060QEJ6|squalene-hopene cyclase|EC 5.4.99.17|Asaia bogorensis|TrEMBL
MLIYSDVLERHEAEIPAEADMGQVRQAIDSAHAALSNRQNDDGHWVFELEADATIPAEYV
LLEHYLDRIDDEKQARIGNYLRRTQGSHGGWALYHDGGFDLSASVKAYFALKAVGDDIEA
PHMKRAREAILDRGGAARANVFTRIQMALFGEVPWRATPVMPVELMLMPKAALFSMWNMS
YWSRSVVAPMLVLRTLEPRAINPRNIHIQELFITPPEEVKDWIRGPYRSIWGHVFKKVDT
MLRPIEPRFPAALRKKAIKVALDFIEPRLGEGGLGAIYPAMANVVMMYRGMGVPDNDPRV
ELAWKGIQELLVSNGDETYCQPCVSPVWDTGLSGLALAEASSGPDATRPKETREALRRSM
DWLRKRQILNVKGDWAINCPDVRPGGWAFQYENDYYPDVDDTAVVGMLLNREDPEGNQEA
ISRAREWIVGMQSTNGGWGAFDIDNDLDALNHIPFADHGALLDPPTADVSARCVSFLCEL
GFPEDRPVIERGLAYLRREQEPEGCWFGRWGTNYIYGTWSTLCAFNIAGVPHDDPAVERA
VAWLESVQREDGGWGEDCASYEGATPGEYDKSLPTQTAWAILGLMAVGRRETPAVKRGIS
YLVAQQNGQGEWEEQPYNAVGFPKVFYLRYHGYKQFFPLMALSRFRNLGLSNSGRVEHGF
>A0A7G7G035|squalene-hopene cyclase|EC 5.4.99.17|Metabacillus sp. KUDC1714|TrEMBL
MITNEIISDEISRRVDEIIKLQQEDGSWKFCFEGGLMTDAFMIMTIRSLEIEDEEILIEK
LTKRIITLQSNIGIWKAYPDEKDGNLSTTVQAYTALLYSGLYSREHHILQEAERFIRKNG
GLSNTHFMTKWMLAVNGLYRWPKLFYIPMTFLLIPPSYPLNFYQFSTYARIHFVPMLIAA
NKKYSIQSKFKPNLDHLFDRNLTDQLDQWDLSHHTRTQNPFITEMKNLLQLPIYLHRLGY
DRAERYMLQRIEGDGTLFSYASATFFMIYALLALGYEKKAPIIKRSVDALKQLITSKCNG
IHLENSTSTIWDTALISYALQETNVSLYTKAIKNSTTYILSKQHSKKGDWKIHNQNIVPG
GWGFSHNNTINPDNDDTSAALRAITRSALTNNRIHFAWNKGVTFLLSMQNSNGGWAAFEK
NTDFELLTYLPLENAKDAAIDPSTADLTGRALEFLGNYAGLTLNHPSIKAGVNWLLNNQE
SNGSWYGRWGVCYIYGTWAAVTGLVAVGVSPTFPAIQKALKWLESIQLGDGGWGESCSSS
EKKQFIPLHFSTPSQTSWALDTLIQANDINSESVQKGVAFLLNETNSKESSSYPTGVGLP
GQFYINYHSYNYIFPLLTLSHYLKVHLQNP
>A0A7C3RZ55|squalene-hopene cyclase|EC 5.4.99.17|bacterium|TrEMBL
MSLHLESASHPEIFRLSRANEFVARVDWVIARAARSLLELQAPEGYWNAPLEANAQMNAE
FIIFNHFMNRVDRELEARLARFLLDRQQDDGSWNIFPGGEGYASYTIEAYAALKLAGYPA
EAPALARARQWIMSHGGIEHAGTLARFYLAAIGQVPWDSTAACPVELMLIPERFPLSIYA
LGSWARGTFVALALLQATRPVVGIDQSRGIRELYTRAPHLTRFHQPTGRRAVSLRNFMNL
LDRGLGFYNRHHIRRLRRRAMSLAERWLLAHQEANGSFGGIEPCYLLSPMALRGCGYPAD
HPVIEKALEASRELVWEMGDKALYMPCVSPNWNTGLAMKALLVSGIPATHPAMTRAARWL
VEHQIFERGDWAVKRPALAPGGWAFEFFNNAYPDVDDSAVIVAALSRAAAGGAADSQGLA
RAIAAGANWTIGMQSRDGGFAAFDPDTDHRWLNHLPLADVEAVTDPSCPDLTGRVLEMMG
TLGYRQDHPAAKRAIEWLAREQSAEGSWWGRWGVNHIYGTFSALVGLRAIGFDLAQPMVR
RAVEWLKSKQNLDGGWGESCLSDRDPSWRGRGPSTASQTAWALLGLLAGEDALSENVLRG
VRWLVQRQNDAGAWDEREFTGNGFPNHFYMRYYLYPHYFPLMALGEFRARVSKITAS
>A0A4P7C4U6|squalene-hopene cyclase|EC 5.4.99.17|Nitrosococcus wardiae|TrEMBL
MTRALRQAPESAGAIDIAASPATEALPQDIHRTKLSTAITAARDALLKLQHADGHWCFVL
EADCTIPAEYILWNHFTGELEPELERKLAARLRAKQADHGGWPLYEGGDLDISCSVKVYY
ALKLAGDDPHAPHMIRAREAILAQGGAARANVFTRLALAMFAQIPWRGVPFIPVEIMLLP
HWFPFHLNKVSYWSRTVMVPLSILYSLKGQAQNPRDVHIQELFTTPPEQERHYFPIRSRL
NKVLLYVERTARLLEPLIPSALRRHAMKKAEVWFTARLNGEDGLGGIFPAMINAHEALIL
LGYGPDHPLRVQAKKAIQNLVVEEGDSAYCQPCLSPVWDTGLASLALQETEGGHTTAPVI
HALDWLKERQILEQPGDWQEQHPHLKGGGWAFQYNNSYYPDLDDTAVIAWAMDQAAAPEH
YGESIQRACDWLCGMQSRNGGFAAFDADNTYYYLNEIPFADHGALLDPPTADVSARCVAL
LGRLNQPQYGESLKRALDYLHQEQEANGSWFGRWGTNYIYGTWSVLTALEQAGVDPQERF
IRRAADWLKQVQRSDGGWGEDNYSYFDTSLAGRYQECTPVHTAWALLALMAAGEADSEAV
KQGIAYLLQTQQEDGLWDHPAFNAPGFPRVFYLRYHGYDKVFPLWALARYRNHLNRQC
>A0A4D9CK79|squalene-hopene cyclase|EC 5.4.99.17|Mastigocladus laminosus UU774|TrEMBL
MQIQDRVTASKVPDAIATSQKYLLSIQKPQGYWWSELESNVTITAEVVLLHKIWGTDKSR
PLHKVEAYLRSQQREHGGWELFFGDGGELSTSVEAYMALRLLGVAPTDPAMIKARRFIVE
RGGISRTRIFTKLHLALIGCYSWQGVPSLPPWVMLLSENFFFNIYEMSSWARSSTVPLLI
VCDRKPVFRVDPAFNLNELYAEGIEKVKYELPSNGNWGDIFLTLDSGFKLAENLNLVPFR
TEGIKAAEKWILERQEATGDWGGIIPAMLNSLLALRCLDYNPADPIVERGLQAVDNFAIE
TADTYQVQPCVSPVWDTAWAIRALVDSGLSPNHPAVVQAAEWLLSKQILDYGDWAVKNRQ
GKPGGWAFEFDNRFYPDVDDTAVVVMALNQVELPNEKLKHQAMVRAVDWVASMQCKPGGW
AAFDLDNDQDWLNQIPYGDLKAMIDPNTADVTARVLEMLGSCQLSIDTENQQRAIKYLLN
EQESEGCWFGRWGVNYIYGTSGVLAALSLVAPQTHRHNIEQGATWLVSCQNSDGGWGETC
RSYDDPSLKGKGRSTASQTAWALIGLIAAGRATGNFAKLAIEQGIDYLLVTQLPNGSWDE
ADFTGTGFPSHFYLKYHLYQQYFPLIALGQYQQLFA
>A0A6P1KRR6|squalene-hopene cyclase|EC 5.4.99.17|Nostoc sp. ATCC 53789|TrEMBL
MQTQDRVKVNQIAEAIAASQQYLLSIQNPAGYWWAELESNVTITAETVLLHKIWGTDETR
PLHKVEAYLRQEQRQHGGWELYYGDGGELSTSVEAYMALRLLGVPASDPAMIRAKAFILQ
RGGISKTRIFTKLHLALIGCYNWRGIPSLPPWIMLLPKAFPVNIYEMSSWARSSTVPLLI
VCDRKPVFITDPTINLDELYAEGVDQVRWELPQSGDWTDLFLTLDQGFKWAESLNLVPFR
EEGIKAAEKWILERQEATGDWGGIIPAMLNSMLALRCLDYDRSDPIVERGLQAIDNFAIE
TENSYRVQPCVSPVWDTAWAIRALVESGFAPDHPAVVKAGEWLLQKQILDYGDWAVKNRQ
GKPGAWAFEFDNRFYPDVDDSAVVVMALHLAKLPNEKIKQAAIARAVNWIASMQCKPGGW
AAFDLDNDQDWLNSIPYGDLKAMIDPNTADVTARVVEMLGACDLSIDSDNLERSLTYLLR
EQETEGCWFGRWGVNYIYGTSGVLSALALIDPQRHKLSIERGAAWLVGCQNPDGGWGETC
RSYDEPSLKGKGNSTASQTAWALIGLLAAGEATGKLALEAIEQGIGYLVATQKSDGTWFE
ADFTGTGFPCHFYLKYHLYQQYFPLIALGRYQAVMGSMNLSLS
>A0A840AE99|squalene-hopene cyclase|EC 5.4.99.17|Roseococcus suduntuyensis|TrEMBL
MNVLRQPIGAALPQHSDPSALDHAVESAAAHLLARQRPDGHWVFELEADATIPAEYLMLK
HFFGQIEPEREARIGRYLRRVQAEQAGNTGGGWPLFHGGPLDISCSVKAYLALRLIGDAP
DAPHMIQARDAILAAGGAERSNVFTRSSLALYGIVPWRAVPVMPPEIMLLPRWFPFHISK
ISYWARTVLVPLTVVMERRPQAANPRGVTINELFRTPPEQVREWPGGAHQAEPWSSLFKG
LDGALHRARKIFPSSHRSRAEAACERFVTERLNGEDGLGAIYPAMANAILMYHCLGVPAD
DPRVVTAWSAIEKLVEDRPAGGAGQEDEDETYVQPCLSPIWDTALVSHALLEAGGEAQVQ
AAGQGLRWLVGREIRDVRGDWAWKRPHLQPGGWAFQYANAHYPDVDDTAVVVLAMDRWRG
ATGAADAEMDGAIQRATDWTVGMQSRGGGWGAFDADNTFHYLNHIPFADHGALLDPPTVD
VSGRCLAMMAQLGRGDEAAAKSAIEYLLREQEADGSWYGRWGVNYVYGTWSALTALNAAG
LPHNHPAMRRAVGWLLERQNEDGGWGEDGMSYPARGGTRPDAREAAPSSASQTAWGMLAL
MAAGEAGHPAVQRAAEWLMEHQTADGDWPEDDYTGTGFPRVFYLRYHGYRRIFPLWALAR
LRNLRASNTKRVAFGL
>A0A6L6QCV4|squalene-hopene cyclase|EC 5.4.99.17|Massilia eburnea|TrEMBL
MAQVRQATSQSVPCDAESAIEQALDAILSRQREDGHWLYELEADSTITAEYILLVHYLGE
DHDPELEERMGRYLRRVQGRDGGWPLFHEGEADVSASVKAYFALKMLGDSPDAPHMQRAR
ARILQLGGAENCNVFTRTLLALYGFLPWRSVPMMPVELLLLPRWAPFHISKVSYWSRTVV
VPLLVLNSLRPVARNPRGVKIDELLANPLQKAGLPPCAPHQHRGWYSIFRGIDMVLRAGE
GLIPRPVRRHALKRAEQFVRERVNGEYGLGAIFPAMVNAVLMFDVLGVPRSDPTVEMARR
SIDALLVDRVDESYCQPCQSPVWDTALACHALLEVSSSKASAAAARGLQWLRRLQVLDHW
GDWKVRRPHVRPGGWAFQYENAYYPDVDDTAVVAMALHRFTQTLGEHVPHSDPALPPSSE
AIERAREWVVGMQSANGGWGAFEPENTHYYLNNIPFADHGALLDPPTADVTARCLSMLAQ
MEGGASSPEAQLALAYLLDEQEENGSWFGRWGTNYLYGTWSALCALNAAGLDGGHPAVKR
AAHWLLSVQNEDGGWGEGGDSYRIDYSGHAESVSTPSQTAWAIMGLMAAGQGRHEAVERG
IAYLVETQRDDGTWHEEHFTAVGFPRVFYLRYHGYAHYFLLWVLARYANLHRDGASPTRW
GM
>A0A846A793|squalene-hopene cyclase|EC 5.4.99.17|Okeania sp. SIO2C9|TrEMBL
MTEKNKVKKSILASQEYLLNLQKPQGYWWDELESNVTITAEIVLLHKIWQTDKKRPLDKA
KNYLISQQREHGGWELFYGDGGDLSTSVEAYMGLRLLGVAKTDPIMLKAQDFIIKKGGIS
CSRIFTKLHLALIGCYNWQGIPSIPPSIMLLPEDFPFTIYEMSSWARSSTVPLLIVFDKK
PIFSVNPTINLDELYAEGINNASFELPRQYDLTDLFLGLDKAFKFAENFNLMPLREEGLK
AAEKWILSRQEVTGDWGGIIPAMLNSMLALRCLEYDVADPVVVRGLEAIDRFGIETEDSY
WVQPCVSPVWDTAWVIRSLVDSGIPSSHPAVVKAGEWLLQQQILDYGDWAVKNKLGKPGG
WAFEFINRFYPDIDDTAVVVMALDAVELPDKELKSQAIARAMEWVASMQCQPGGWAAFDV
DNDQDWLNGIPYGDLKAMIDPNTADVTARVLEMVGCCRLSMDSWRVKRAIAYLEREQEGE
GCWFGRWGVNYIYGTSGVISALTVVAGESHRVFIERAATWLVGCQNSDGGWGESCRSYND
PSLKGKGKSTASQTAWALIGLLAAGEATGNFAREAIDGGVDFLVSTQKDDGSWLESEFTG
TGFPCHFYIKYHFYPQYFPLMALGKYENLLSG
>A0A7Y7IY78|squalene-hopene cyclase|EC 5.4.99.17|Nguyenibacter vanlangensis|TrEMBL
MMANATEMLDTLLDADASADAGTAVPMDAPMAAIDRAVEAAHGALGRRQNADGHWVFELE
ADATIPAEYVLLEHYLDRIDPALQARIGVYLRRIQGAHGGWPLYHGGRFDISASVKAYFA
LKAIGDDIDAPHMARARAAILDHGGAERSNVFTRFQLALFGEVPWHATPAMPVELMLLPR
KALFSVWNMSYWSRTVVAPLLVLAALRPRAVNPRGVHVPELFVTPPERIRDWIRGPYRSP
LGRVFKYVDKVLRPAERMIPEKTRRRAIAAAVDFIEPRLNGVDGLGAIYPAMANTVMMYR
ALGVPDSDPRAATAWESVRGLLVEHGDEAYCQPCVSPIWDTGLAGHAMIEAASGPQGVRP
AETKRTLAAAAAWLRDRQILDVKGDWAINCPDVPPGGWAFQYRNDHYPDVDDTAVVGMLL
HREGDPASEEAIARARLWIIGMQSSNGGWGAFDIDNNMDFLNHIPFADHGALLDPPTADV
TARCISFLAQLGHAEDRPVIERGLAFLRSDQKPEGCWFGRWGTNYIYGTWSVLCAYNAAG
VSRDDPSVRRAVDWLRAVQREDGGWGEDCASYEGAAPGRYTESLPSQTAWAVLGLMAAGL
RDDPAVARGMAYLTRTQKPDGEWDEDPYNAVGFPKVFYLRYHGYRQFFPLLALARYRNLA
SSNTRQVAYGF
>A0A7Y7NEI5|squalene-hopene cyclase|EC 5.4.99.17|Desulfuromonadales bacterium|TrEMBL
MIPYKHAISNALTSFNYLYTSIDDLETSDKEVKISHLVKNVVKENEIVVRTSLDFAIKLT
NDFFLREQLPAGYWWAELESNVSITSEYIMLFHFLGIVNKERERKMADYLLNKQTKEGFW
TIYYGGPGDISITTEAYFALKLSGCSADHSAMAKARAFILEKGGVIKCRVFTKIFLALFG
EFPWLGIPSIPIETMLLPNWAYFNMYELSSWSRATIIPLSIVMSERPVKKPPPWASVQEL
YTNPPQATDYSLSKDHCFLTWENVLIAMDRMHKIYEGSPIRPFKKKAMATAEKWVLDHQE
STGDWGGIQPVMLYSVLALHCLGYANNHPAVAKGLVALANFCIENENELVLQSSISPVWD
TALAVKALVDSGVPTDHPALTKSALWLLEREARKPGDWRVKSPDLEPGGWAFEFINDYYP
DVDDSVFVMLAIKDIQVRDQKIKEDAIKRGITWCLGMQSKNGGWGAYDKDNTKHILNQIP
FSDMEALIDPPTADLTGRMLELMGTYGYSKEFPAAARAVEFIRKTQEPEGPWWGRWGVNY
IYGSWSVLSGLSAIGEDLALPYIRRAVDWLNLKQNKDGGWGETCESYHDRSLAGVGESTS
SQTSWALLSLMATGEVHSSQVTEGISYLISTQRPDGAWDEDHYTGTGFPKFFMIKYHIYR
NCFPLMALGTYRKLTEKKN
>A0A6G4XDE0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces mesophilus|TrEMBL
MTATTDGSAGAIPPDAPAASESVRTPAALDGARQANQRAIEYLLDHQDDEGWWKGDLETN
VTMDAEDLLLRQFLGIRDEKTTQASALFIRGEQRADGTWATFYGGPGELSTTVEAYVALR
LAGDDPEAEHMAKASAWIRAEGGIASARVFTRIWLALFGWWKWDDLPQLPPELIYFPKWF
PLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDARDPNPYKPLAPAASWDGAF
QRLDKVLHTYHKVAVPGLRRMAMRSAGRWIVERQENDGCWGGIQPPAVYSVIALHLLGYD
LDHPVLREGLASLDRFAVWREDGARMIEACQSPVWDTCLAVIALADAGLPADHPALVKAA
DWMLVEEIARPGDWSVRRPQLEPGGWAFEFHNDNYPDIDDTAEVALALRRVQHPDPARVD
AAVKRATTWTYGMQSKNGAWAAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVVEFLA
GEGKAHDPRTRRGITWLLAEQEAGGAWFGRWGVNYLYGTGSVVPALVAAGLPAAHPAIRR
AVDWLESVQNDDGGWGEDLRSYVDESWVARGESTPSQTAWALLALLAAGERDSKAVERGV
AWLAETQRADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLGGQGHEGG
>A0A494Y3I2|squalene-hopene cyclase|EC 5.4.99.17|Cohnella endophytica|TrEMBL
MGNFQSLIEEEIHSQLSALIRQQKQDGSWRFCFENGTTLDAYVIILLRTLDVRNEVLIRQ
LHDRILAEQQPDGCWKWYRDEEGGNLSASVEAYYALLYSGFTRMTDEPVLRAKSYIQSKG
GIGKTTSILTRAILAATGHGKWPMSIASIPLEALLLPVSFPINVFEFSGYSRVHLIPMLI
MADRNFSLKTEHVPDRYDLSSDDMDYDNRLSRGVQEMVGHIQAGLSKLTGTPRQLREAAK
AKAEQFLLQRIEPDGTLYSYASCTILMIFALLALGYEKNHPLITRAVQGITDMQCRSIGR
TTIQNSTSTVWDTALIASAMQEAGVPDHHPAIRKAAAYLLARQHDKKADWSIHNSDTVPG
GWGFSDTNTLNPDVDDATAALRAIRRLSRTEPLFRESWNRGLNWVLSMQNKDGGWPAFEK
NADNKMLTWLAIDGAKSAAIDPSEADLTGRTLEYLGNFAGLGMGHEFMKRGTDWLKNHQE
RDGSWYGRWGICYIYGTWAALTGLRAAGIDSDDPTIRKGTDWLLSIQNTDGGWGESCNSD
RLFRYVPLGESTPSQTAWAVDALIAVHPRPSAAIDKGIHRLIASLHDTGWAASYPTGAGL
PGNFYSHYHSYRYIWPLLALSHYRKKYGEHESPR
>H1KQ51|squalene-hopene cyclase|EC 5.4.99.17|Methylorubrum extorquens DSM 13060|TrEMBL
MREAAVSKVETLQRPKTRDVSLDDVERGVQSATRALTEMTQADGHICFELEADATIPSEY
ILFHQFRGTEPRPGLEAKIGNYLRRTQSKVHGGWALVHDGPFDMSASVKAYFALKMIGDD
IEAPHMRAVRKAILQRGGAANANVFTRILLALYGEVPWAAVPVMPVEVMHLPKWFPFHLD
KVSYWARCTMVPLFVIQAKKPRAKNPRGVGVAELFVTPPDSVRTWPGSPHATWPWTPIFG
GIDRVLQKTQDHFPKVPRQRAIDKAVAWVSERLNGEDGLGAIFPAMVNSVLMYEVLGYPP
EHPQVKIALEAIEKLVAEKEDEAYVQPCLSPVWDTALNSHAMLEAGGHQAEANARAGLDW
LKPLQILDIKGDWAETKPNVRPGGWAFQYANPHYPDLDDTAVVVMAMDRAQRQHGLVSGM
PDYSESIARAREWVEGLQSADGGWAAFDADNNHHYLNHIPFSDHGALLDPPTADVTARVV
SMLSQLGETRATSRALDRGVTYLLNDQEKDGSWYGRWGMNFIYGTWSVLCALNAAGVDPQ
SPEIRKAVAWLIRIQNPDGGWGEDASSYKLNPEFEPGYSTASQTAWALLALMAAGEVDDP
AVARGVNYLVRTQGQDGLWSEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKRGNS
RQVQFGM
>A0A7H8N3E6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces buecherae|TrEMBL
MTATVVETTTVLTAARQATARAVDHLLARQDKEGWWKGDLETNVTMDAEDLLLRQFLGIQ
NPGTTAAAARHIRSQQRPDGTWATFHGGPPDLSATVEAYVALRLAGDEPDAPHLAAAAAW
VREAGGIAASRVFTRIWLALFGWWSWDDLPELPPELIYLPKWAPLNIYDFGCWARQTIVP
LTIVSAKRPVRPAPFALDELHTDPRRPNPPRPLAPATTWDGAFQRLDRALHSYRKVAVRP
LRRAAIRSCARWIIERQENDGCWGGIQPPAVYSVIALHLLGYDLEHPVLRAGLASLDRFA
VWREDENGERVRMVEACQSPVWDTCLATIALADAGLPDDHPALVRAADWMLDEQVYKPGD
WSVRRPELRPGGWAFEFHNDNYPDIDDTAEVVLALRRVSHPDPQRVERAIQRGAEWNLGM
QSSNGAWGAFDADNVSPFPNKLPFCDFGEVIDPPSADVTAHVVEMLVALGERGDPRTQRG
IDWLLAEQEPNGAWFGRWGTNYLYGTGSVVPALVLAGIPTTHASIRRAVSWLESVQNEDG
GWGEDQRSYRERAWVGRGESTASQTAWALLALLAAGERESECVRRGIAWLVETQRPDGGW
DEPYFTGTGFPWDFSINYHLYRMVFPITALGRYIHAQPFGAERQGA
>A0A5C5SH10|squalene-hopene cyclase|EC 5.4.99.17|Reyranella sp. CPCC 100927|TrEMBL
MDQISALDMTTVEDVIGKATKALLEQSKGDGHWVFELEADATIPSEYVLLVHYLGETPDL
TLERKIGHYLRRIQGDHGGWPLFHDGAFNISATVKAYFALKMIGDSVDAPHMVRAREAIL
AHGGADKANVFTRMQLALFGETAWRNTPTVPAELILLPRWFPVHLSKMSYWARTVIVPLL
VLQALKPLARNPRNIHVPELFVPGATTASQRAPHQSAAWSAFFVGLDRVLKVVEPLWPRG
LRRRAIARCQEFVVERLNGEDGLGAIYPAMANSVMMFDALGYPEDHPDRAIARQSLEKLL
VVKDDEAYCQPCVSPIWDTALACHALMEAKSETADAAVNQALEWLKARQVLDVKGDWAEE
RPGVRPGGWAFQYNNAHYPDLDDTAVVVMALDRARKTPGADHALAIDRGTEWVVGLQSRN
GGWGAFDADNSYHYLNNIPFADHGALLDPPTEDVTGRCIGMLAQLGEPADSPRMKAAVDY
LARVQLPDGSWFGRWGVNYIYGTWSALAGLNAVPVDPQSPMIRRAVDWLVSIHNPDGGWG
EDCESYKLDYKGYEPAPSTASQTAWALLGLMAAGEVDHPAVARGIAHLKRTQQDDGLWAQ
QHYTGGGFPRVFYLRYHGYPKIFPLWAVARYRNLKAGNSRHVAYGL
>A0A839E0P5|squalene-hopene cyclase|EC 5.4.99.17|Halosaccharopolyspora lacisalsi|TrEMBL
MTDSLRRETERTEVIERDFDEHVPVSDRGVTALAAGRDHMLSLQHPGGWWKGELQTNVTM
DVEDLLLRQFLGIRTETETAEAARWIRSQQRADGTWGNYYGAPGDLSTTVEAYVALKLAG
DSVDDEHMALARRWILEQGGIERTRVFTRIWLALFGEWSWEKLPAMPPELILLPPWFPLN
VADWGCWARQTIVPLTVVCTMKPRRELGITVTELRSGRVPAASKAPLLSWERGFNGLDRV
LHRYHRHSVRWLRRHSMRRAAEWIVARQEADGCWGGIQPPWVYSLLALNLLGYPLDHPVM
REGVSGLEGFLIREPTESGVVRRLEACQSPVWDTVLGIQALCDAGVPADHEALRSAGEFV
RSEEIRVRGDWAVRRPELAPSGWAFEFENDGYPDVDDTAEALLALDRIGDPDDEATRSAI
TRGEQWLRGMQSRDGGWAAFDADNTRELVNKLPFCDFGAVIDPPSADVTAHVVEALCTVG
SGQDDVVGKGVRWLLTHQEADGSWYGRWGANHVYGTGAVVPALVRSGLLPEHAALQRASR
WLETHQNDDGGWGEDMRSYDDPSWIGHGTSTASQTAWALMALLALGRHDTEVVRAGVDYL
VTTQLPDGSWDEPQFTGTGFPGDFYINYHLYRQIFPLNALGRYRTAVEGG
>A0A7K2ARN1|squalene-hopene cyclase|EC 5.4.99.17|Acidimicrobiaceae bacterium|TrEMBL
MDNHQAHQSVREAVERTQQYFLRTQRDDGCWWGELESNPTIEAEYIMLTRFLGSDEGDRT
GRVAADIRRRQQPDGSWRMYFGAPGDLSTTIECYFALKLAGDPPDAPHMAQARAFIIENG
GIPKSRVFTKIWLALFGQWDWRAPPSMPPEIMLLPKWAPFNIYRFSSWARATIVPMTIVL
TLKPTRPPPAGAGIEELRRDGPEALAVSRFKPNPLSVQGGFLLMDRALRLWRGLRLVPGR
RRALRAAVDWIVSHQEGDGSWGGIQPPWVYSLIALSALGHPLDHPVLAKGLQGFRNEWSL
PSPDGAALRVQACLSPAWDTALAMRGLMDSGVSPDHPAIQRAAEWLVGKEVRYAGDWAVK
RPHLEPSGWAFGFDNVNYPDIDDSSVIVANLALTNLADRASDSAKEATIDRAVDWLTGMQ
SSNGGWAAFDYNNDSRSVTKIPFADFGEVLDPPSADITAHMLEMYGILGYSRWHPAVRRG
LHYLWQQQEPDGSWFGRWGVNYLYGTGAVLPALEALGVDMAQPAVRKAVQWLVDTQNPDG
GWGETCESYVDPTLSGQGDSTASQTAWALIALIAAGEAAGEPVTRGIEFLVATQQADGTW
DEPQFTGTGFPGYGHGDRPTKKGAPADSLQGAEMGAAFMINYHLYRNYFPLWALGRYLAA
VAPRVAQAVPLGRTETETDKSPNAIQEVIDLPTGPSRRARRQRSPMGSHRAVHRPTAPPP
>A0A7J4ZNN6|squalene-hopene cyclase|EC 5.4.99.17|Oryzomonas japonica|TrEMBL
MHSKTKTKLNVIEGGRGAKQAEAGVSANTFLHVESILERAAHQLAALQNEDGHWVFELEA
DVTIPSEYIMLQRFLGRSVDEKTASRLSSYLLDRQLPDGSWPLYAVDGNANISASVKAYF
ALKLLGHDKNAPYMVKARQIILSLGGAARCNVFTRITLALFGQVPWHTPPAMPIEIMLLP
RWFFFHLSKISYWSRTVIVPLLILYAKQPVCALRYNEGITELFTTPPDMLGNLDHFRHRA
WRKNVFIVLDRVLKRTMHYIPKRIRAHALRQAEQWTRARMQGEGGIGAIYPAMANAVMAL
KTLGCREDDPDYVRGIAALDDLLIHRTPAPDAVPHTSPFGGGIDRSSAAPDLLLSRHAST
ARNDHFSLCQPCNSPVWDTCLSLSALVEAGIPGNLFSADEAMKWLFDRQICTPGDWSGNC
PGLACGGWAFQYENTLYPDVDDTSKVLMGLFRAGALEREEYREKIAKAVRWVIGMQNSDG
GWGAFDVDNDYLYLNDIPFADHGALLDPSTSDLTGRCIEMLGMLGYGPDFPPIARGLAYL
EKEQEAFGGWFGRWGVNYLYGTWSVLSGLHEVGEDMQKPYVRKAVEWLVGCQNGDGGWGE
TCASYDDPSLAGSGASTPSQTAWALLALMAAGETDRPEVQRGMQYLVDRYHNGWEERHFT
GTGFPRVFYLRYHGYRLFFPVWALGAYLRRRRGATTVQDAVRRKYMGGVSWLKLQ
>A0A643GA11|squalene-hopene cyclase|EC 5.4.99.17|Oryzomonas sagensis|TrEMBL
MNSSKYPISTALTSFNLETAAPTAPAIDPPKKTVAKVHHLPPSIWKKMVGDAKSPLDKAI
ERTRDFFFREQLPDGYWWAELESNVTITSEYVMLFHFLGMVDKVRERKMARYILGKQTEE
GYWAIWHTGPGDLSTTIEAYFALKLAGYPADHPAMRKAREFILANGGIIKARVFTKIFLA
LFGEFSWLGVPSMPIELMLLPNWAYFNVYELSSWARGTIIPLSVVMAERPVRKLPPWARV
KELYVRPLRPTDYTFTKEDGILTWKNFFIGVDHLCKVYESSPIRPFKKKATSVAEQWILD
HQEPTGDWGGIQPAMLNSILALHCLGYANDHPAVVKGLEALANFCIEDEEGLVLQSCISP
VWDTALALVAMQEAGVPADHPALVKAAQWLLDLEVRRKGDWQIKAPELEPGGWAFEFLND
WYPDVDDSGFVMLSIKDIKVRDRKHKEQAIKRGISWCMGMQSQNGGWGAFDKDNTKYLLN
KLPFADLEALIDPPTADLTGRMLELMGNFNYSKSHPAAEHALEFLQKEQEPEGPWWGRWG
VNYIYGTWSVLCGLQAIGEDMSRPYVKKAVNWFKSKQNMDGGWGEVCESYFDRSLMGSGP
STPSQTGWALLALMAAGEVHSKTVARGIDYLLNSQKQDGTWDEDAFTGTGFPKFFMIKYH
IYRNCFPLTALGKYRRLLAESGEKK
>A0A5C1MCJ7|squalene-hopene cyclase|EC 5.4.99.17|Geobacter sp. FeAm09|TrEMBL
MIHSKTKTKLNIIEGGRSAKQAEAGGSADTFLHVEAVLEKAAHQLASLQNDDGHWVFELE
ADVTIPAEYVMLQRFLGRSIDDATASRLSSYLLDRQLPDGSWPLYAVDGNANISASVKAY
FALKLLGHDKNAPHMVRARQIILALGGAARCNVFTRITLALFGQVPWHTPPAMPIEIMLL
PRWFFFHLSKISYWSRTVIVPLLILYAKQPVCALRHDEGIAELFSTPPDMLGNLDHFRHR
AWRKNVFIVLDRILKRTMHHIPARVSARALRLAEQWTRERMQGEGGIGAIYPAMANAVMA
LKTLGCREDDPDYVRGIAALDDLLVHRTPVPDAPPPSPFAGGIDRSSAAPDLLPSRHAAT
ARDDHFSLCQPCNSPVWDTCLSLSALVETGIPRNLFSVDEAMKWLFDRQIATPGDWSGKC
PDLACGGWAFQYENTLYPDVDDTSKVLMGLFRAGALEREEYREKITTAVRWVIGMQNSDG
GWGAFDIDNDYLYLNDIPFADHGALLDPSTSDLTGRCIEMLGTLGYGPEFPPIAQGIAYL
KQEQEAFGGWFGRWGVNYIYGTWSVLSGLHQVGEDMQKPYVRKAVEWLVGCQNGDGGWGE
TCASYDDPSLAGSGASTPSQTAWALLALMAAGETERPEVQRGVQYLVDRYHGGWEERHFT
GTGFPRVFYLRYHGYRLFFPVWALGAYLRRRRGAPTVQDAVRRRYMGGVSWLKLQ
>A0A6N0LMY7|squalene-hopene cyclase|EC 5.4.99.17|Nostoc sp. TCL240-02|TrEMBL
MQTQDRVKVNQIADAIAASQEYLLSIQNSAGYWWAELESNVTITSEAVLLHKIWGTDQTR
PLHKVEAYLRQEQRQHGGWELYYGDGGELSTSVEAYMALRLLGVPANDPAMIRAQAFILQ
RGGISKTRIFTKLHLALIGCYNWRGIPSLPAWVMLLPKAFPVNIYEMSSWARSSTVPLLI
VCDRKPIFLSDSAINLDELYVEGVDRVRWELPRSGDWTDLFLTLDQGFKLAESLNLVPFR
EEGIKAAEKWILERQEATGDWGGIIPAMLNSMLALRCLDYDRSDPIVERGLQAIDNFVIE
TENSYRVQPCVSPVWDTAWAMRALVESGFAPDHPAVVKAGEWLLQKQILDYGDWAVKNRQ
GKPGAWAFEFDNRFYPDVDDSAVVVMALHLAKLPNEKIKQAAIARAVNWIASMQCKLGGW
AAFDLDNDQDWLNSIPYGDLKAMIDPNTADVTARVVEMLGACDLSIDSDNLERSLTYLLR
EQEIEGCWFGRWGVNYIYGTSGVLSALALIDPQRHKLSIERGAAWLVECQNPDGGWGETC
RSYDDPSLKGKGNSTASQTAWALIGILAAGEATGKLAFKAIEQGIGYLMATQQPDGTWFE
ADFTGTGFPCHFYLKYHLYQQYFPLIALGRYQAVMGLTNLSLS
>A0A536Z1C4|squalene-hopene cyclase|EC 5.4.99.17|Betaproteobacteria bacterium|TrEMBL
MHSSSREARLTPDPELVARQIPIGPAESSLDRAIETATAALVKRQRADGHWVFELEADAT
IAAEYVVLQHFLGEPNPALEAKIAIYLRRLQGPHGGWSLFHGGDLNISASVKAYFALKLA
GDAPESAHMRRAREAILAQGGAGTTNVFTRILLALFGVISWGAVPIIPVEIVFLPRWFPF
HLSRVSYWSRTVVVPLLVLQALKPRARNPRGVRIDELFPGRRPRARRWARAPHQARARFA
VFAAIDAALRLVEPLIPQRLRRRAIKKAVAFVTERLNGEEGLGAIFPAMANTVMMFDALG
YARDHPHFVTARRAIDKLLVVTREEAYCQPCVSPVWDTVLVCQSLLEVGDNQTRTAARDG
LAWLEKRQVLDAVGDWADQRPHVRPGGWAFQYANPHYPDLDDTAVVVMAMDRFARRRVMR
GEPDFRGAIDRGREWVLGLQSANGGWGAFDVDNTSEYLNHIPFADHGALLDPPTADVTAR
CVSMIAQLGDAADAPVLAKALGFLRRNQEDDGSWYGRWGMNYVYGTWSVLCALSAAGMSP
DAPEIRRAVAWLIAAQNEDGGWGETGDSYRLDHRGLERAPSTASQTAWALLGLMTAGEER
NPAVERGIDYLVRRQGADGFWREPQFTATGFPRVFYLRYHGYAKFFPLWALARYRNLAQS
GERRVRFGM
>A0A536Z1P1|squalene-hopene cyclase|EC 5.4.99.17|Betaproteobacteria bacterium|TrEMBL
PNPALEAKIARYLRRLQASHGGWPLFHAGDFNISASVKAYLALKLVGDSPEAEHMRRARE
AILACGGAGKTNVFTRILLALFGIVSWGAVPIIPVEIVFLPPWFPFHLSRVSYWSRTVLV
PLLVLKALKPRARNPRGVGIDELFPGARARASRWARAPHQSRLRFALFSAIDSILRWLEP
LVPSAIRGRAIDKAVAFVTERLNGDDGLGAIFPAMANTVMMFDALGYERDHPDLVMARKA
IDKLLVVSREEAYCQPCVSPVWDTVLACHALLDVGGKDARAAVRSGLEWLEAKQVLQTIG
DWAERRPHVRPGGWAFQYANPHYPDLDDTAAVVTAMDRFARTRVARGEPDFRSGIDRGRD
WVLGLQSANGGWGAFDADNTSEYLNHIPFADHGALLDPPTADVTARCAGMIAQLGDTAHA
PALAQALDFLRRDQEDDGSWYGRWGMNYIYGTWSVLCALNAAGVSPQAPEVRRAVDWLIA
AQNQDGGWGETGESYGLKDRDRERAASTASQTAWALLGLMAAGEVPNPAVARGIHYLSQR
QGEDGFWREPHFTATGFPRVFYLRYHGYAKFFPLWALARYRNLIGSGERYVRFGL
>A0A5C8U9X8|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium sp. WL19|TrEMBL
MREAFKKVETLQRPKTQEISLDDVEHGVMRATQALTNLVHADGHLCFELEADATIPSEYI
MFHQFRATTIPPDLMAKIGNYLRRTQGKHGGWSLVHDGPFDMSASVKAYYALKFVGDSIE
APHMRRAREAILSRGGAANSNVFTRFLLALFGEVPWRAVPVMPVEIMHLPKWFPFHLDKI
SYWARCVIVPLLVLQAKKPLAKNPLGLGVSELFVTPPDHVRSWPGSPHATWPWTPIFGAI
DRLLQVTQDYFPKKRRQRGIDKAVAWTSERLNGEDGLGAIFPAMVNTVLMYEVLGYPADH
PQVRIACEAVEKLVVVKEHEAYVQPCLSPVWDTALAGHALLEAGGPDAEHQARRGLDWLR
PLQVLDIKGDWAAGRPNVRPGGWAFQYANPHFPDLDDTAVVVMAMDRATRQHGLVADVPD
YAVSIARAREWVEGLQSSDGGWAAFDADNNHHYLNNIPFSDHGALLDPPTADVTARVVSM
LSQLGETRETSKALDRGVKYLLDDQEEDGSWYGRWGMNFIYGTWSVLCALNAAGVDPASP
EIRRSVAWLIRIQNPDGGWGEDASSYKIDPAFEPGYSTASQTAWALLALMAAGEADDPAV
TRGINYLTRTQGADGFWSEERYTATGFPRVFYLRYHGYPKFFPLWAMARYRNLKRSNTRS
VAYGM
>A0A7C5LKK2|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia bacterium|TrEMBL
MIQLKLHHTHELEEQLRVAIAAAQEWLLERQAPDGHWCAELEGDTILESEYVIYLHFTER
LDPTTLRKCANYIRSKLLPDGGVAIYPAGPMEISASVKAYLVLKMAGDPVDAPHMIKTRQ
AILDAGGITRCNTWTKIYLAMVGLYPWDGCPAIPPELMMLPKWFPFSIYNMSAWSRAMFV
PLSIIRSKEPVKPLPPHCQLDELWVGGKDKADIHLPWDPRTLTWRNIFLRIDTFLKFIQR
HHPAPFLRRFAIRRAERWTIEHGRTPGGLGAIIPAMANYVMSLRVLGYANDSYLVAHGIA
ELEKLRIEEEDSLRLQPCVSPVWDTAISLNALHESGLSPDHPSLVAATRWLLDKEVRRPG
DWRVKHSECHRYTEPNKPIGGWFFEYDNEFYPDVDDTIMVLMALNRSQTPFDREKSAAIR
RGIRWVLGMQCRDGGWAAFDKDNDKYIFTKVPFADHNAMIDPSTADITARTLECLSHFGF
TCEDECVQKALDYIQRDQCADGSWFGRWGCNYLYGTWQTLRGLHAIGADMRLPYVRRAVA
WLKNVQNADGGWGESVHSYDDPHYKGIGESTASQTAWALMGLISAGEAHSPEVARGIEYL
LRTQTAEGTWEEHLFTGTGFPKVFYLRYHYYCHYWPLMALGMYARATACDFPPVPRKHEK
SRALKQFYKQPRLYRTMARLRTLAQLRED
>A0A852UPD7|squalene-hopene cyclase|EC 5.4.99.17|Streptosporangium sandarakinum|TrEMBL
MTTETAGDTGGATATTGTTGVAEVAGVTGITAITPAAGTAVPLAAPVIAASAVTVAPAGT
TGLAGRAALALDAACEHLLGLQSPEGWWKGELQTNVTMDAEDLLLREFLGIRTEEDTAAA
ARWIRSEQRGDGTWATFHDGPGDLSTTVEAYTALRLAGEPPDAAHMRAAAGFVRDMGGVE
EARVFTRIWLALFGRWPWERLPALPPEMIFLPPWFPLNVYDWACWARQTVVPLTVVAAHR
PVRPLPFDLDELRTGRRPGGWPRPGWEAAFAALDRVLRRYERRPVPGLRRAALRRAAEWI
VARQETDGSWGGIQPPWVYSLIALHLQGYHLDHPVMRKGVEGIDRFTIREAGTRRLEACQ
SPVWDTVLAVNGLLDAGLSGDHPALLRAADWVLAEEIRGPGDWSVRRPDLPPGGWAFEFD
NDGYPDIDDTAEAVLALRRVRHPGVRPAVDRAVRWMTGMASRDGGYGAFDADNTQVLCTK
LPFCDFGAVIDPPSADVTAHVAEALAHEAPGSPALRRAVVWLLRAQEADGSWFGRWGVNH
VYGTGAVVPALVAAGVRPDGPRIRRAVAWLERHQNADGGWGEDLRSYTDPAWIGRGASTP
SQTAWALLALLAAGERSPAVDRGVAWLADNQRPDGTWDEQYFTGTGFPGDFSINYHLYRL
VFPVSALGRYLRRERRTGGEAPP
>A0A5M8ZKV4|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter sp. DmW_136|TrEMBL
MAADGSALSESRLSSDVLDRAVLSAHTALSQAQQNDGHWVYELEADATIPAEYILLEHFM
DRIDDALEQKIAIYLRRIQSEEHGGWPLYHNGKFDLSATVKAYFALKAVGDDINAPHMQR
AREAILDHGGAERSNVFTRSQLALFGEVPWRATPIMPVELMLLPAKAFFSVWNMSYWSRT
VIAPLLVLAALRPVAANPRQIHVRELFVTPPEKVQDWIRSPYRSAWGYVFKGLDSVLRPI
VPFIPEKTHKKAIQAALDFIEPRLNGKDGLGAIYPAMANVVMMYRAMGVPDKDPRAKTAW
EAVQALIVEKDDEAYCQPCVSPIWDTGLSGHAMIEAASGPNGVAPEKTLGELKKTSAWLR
SKQILNVKGDWAVRNPDLAPGGWAFQYGNDYYPDVDDTAVVGMLLHREGDPANAEAIARA
RAWIVGMQSTDGGWGAFDIDNNKNVLNHIPFADHGALLDPPTADVTARCISFLAQLKNPE
DEPVIKRGLEYLRKEQEKDGSWFGRWGTNYIYGTWSALCALNAAGISHDDPAVVKAVEWL
RSVQQTDGGWGEGCESYEGGPHGTYGESLPSQTAWAVLGLMAAGRRDDPAVTRGIAWLAD
QQDANGEWHEDPYNAVGFPKVFYLRYHGYKQFFPLMALARYRNLESSNTRRVSFGF
>A0A552EM43|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa Ma_MB_F_20061100_S20D|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYPQGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNNWSDVFLWLDGLFKWAEKTNLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALDYDVYDPIVARGLKAVDNFAIQ
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKGVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNKYHHQLQKGANWLSGCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWNE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A7V2XT92|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MNTAASQASRIHPLPVTAPIEARIEQAIRSAQTYLLGRQDPNGYWFAELIGDSTLESDVV
MLMHFLGRVDENKQRRLLKFVLSQQNPDGGWSIYHGSPSDPNATLKAYFALRLAGYTDED
PRLQRARRRILELGGIEACNSYSKFYLALFGQYDWTKLPAMIPEIALLPPLRWGFNLYRI
SSWTRAIIVPMLIIYALRPRVEIPFSVRDLAVPFEPRSPKGLRKKLWHAIFRFADRLLGF
YNRLDIKQVRDRAIRAAQAWMIERMMKPGGLAAIYPPMVNTIIALKALGYPPDSPEMRKA
LRDLEELQIADDGIMRVQPCFSALWDTAWAVNILARSGLARSDAVQRGADWLLSKQIFTG
GDWQVNCPGVEPAAWAFEFDNPVYPDTDDTCTVLMALHFAGRQHEPGFAKAVRWLEAMQN
PDGGWGAFDRNIDWKALENIPWADHNALLDPSTVDFTGRIIETFGYLGRTEADPVVSRAV
QFLRRSQEPDGSWFGRWGVNYIYGTWQVLVGLRAVGVDMKADWVRRAADWLRSVQNADGG
WGESCRSYDDPLFKGRGPSTPSQTAWGLMGLIAAGGTLDDAPVRRAVEHLLLTQRIVGGW
DETEHTGTGFPRVFYLIYTLYRDYFPLLALQFVRETLRKSPNRPAGA
>A0A7Y3UBY7|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MPRLPSHHDMTVTNPPTSVSTLTEQAHRACDRAVSALVDMQHEDGHWCSRLQGDSILCSE
YILMKWILNQEDDPRLPRILAHLLAQQRPDDGAWVQYPGAAPDVSATVKAYLCLLLSGSH
SDNDETMRRTEHLIRAHGGAETVNTFSMFYFACLGLVDWDACPAIPPELVFQPHWSPFHL
AKMSAWSRTMVLPLAICSALRPVRQLPDQVHRAFARLFNDRAYQHRICRSRSQQHRIMGA
VFHQCDDWLKSVNHAGAGNWPLRRRALQEAERWILDRAQPHTTEGLGAIFPPMVYLQIAL
YALGYPEDHPTCRQARDDLDALMLEVDPTDPSSPIDIQPCFSPVWDTGIALHALTECGYH
LNRDIPGRLIRRAADWLADRQTTHAGDWSAAVPVEPGGWSFEYRNEWYPDVDDTAMVLMA
LHGSDSAQSTFGPNIDRGLRWLLAMQCEDGGWAAFDRTVNRPWLEALPFADHNAIQDPSC
PDITGRVLECLGKLGRSHHDPAVQRAIRYLRNKQEPEGCWFGRWGVNYIYGTWEVLEGLR
AIGCDMTQPWIRRAGLWLLDVQQADGSFGESPDTYEKNQIKGVGRPTASQTAWGAMGLLA
VFGAEHPAVKRAIGRLCETQLSEGEPRCDHENPAGTWAETEFTGTGFPRVFYLRYHLYRT
YFPMMALARYLRSNGSRSHPAAGVH
>A0A3L7QVX9|squalene-hopene cyclase|EC 5.4.99.17|Planctomycetes bacterium|TrEMBL
MAFIVFNSFNTTSAMERIPVPVAFKQKKHSTFNPVAGSNYNLLDKALAAVINGRNFLIQH
QQKDGHWVAELQGDTILESEFVLLRAFLGKENDEICQKCARYIQSQCRAEGGWSNFPGGP
FDLSVSTKAYFALKLTGVSTQLPWMKLAREKILQAGGAENCNSFSRFYFALLGEYSYQNC
PEVPPELLLLPSWFPVSIYSMSSWTRTILVPLSIFSAIKPSIKLPQEKGIRELFIADPWQ
AKWPSAPSKELFSWRNFFLLADLAIKKIAPRIPFLRNYAVSKAAHWMREHFQYSDGVGAI
FPPMIYTVVALKCLGVQESSPEMQWAMKQLLDLMIEENGSIRLQPCVSPVWDTALATIAV
ADAGQPEDDLKLKKAVDWLLKKEVSGKIDCSTNHPDMKPAGWFFEYNNQFYPDIDDTAMV
IIAMVKTNSHHRPECIAAIERSVRWIFLMQNRDGGWGAFDKDIDQEFLTKVPFADHNAML
DPTCPDISARVLEALGELGYNANEIHIQKAIEYIRSSQEPWGAWVGRWGVNYIYGTWQVL
LGLKAIGFDMGDPMVARAVQWLKGCQHEDGSWGETCATYDDPSLAGQGDATPSQTAWAVL
GLIAAGEEHSDSVRNGIAYLVNTQNSEGDWTENFFTGTGFPKVFYLKYHYYRVYFPLMAL
SRYCRLLGYAFEQNTY
>A0A7W4K2Q6|squalene-hopene cyclase|EC 5.4.99.17|Gluconacetobacter dulcium|TrEMBL
MMVNATDSLERPSAGAADPVVPMIEIDQAVDSAHAALDRRQNDDGHWVFELEADATIPAE
YVLLEHYLDRIEPDLEARIGVYLRRIQGDHGGWPLYHGGRFDLSATVKAYFALKAIGDDI
DAPHMARARAAILDHGGAERSNVFTRFQLALFGEVPWHATPAMPVELMLLPRKALFSVWN
MSYWSRTVIAPLLVLAALRPRAVNPRDVHVPELFVTPPAQVRDWIRGPYRSTLGRVFKYV
DKVVRPGERLIPEATRRRAIKAAVDFIEPRLNGVDGLGAIYPAMANSVMMYRALGVPDSD
PRAATAWESVRRLLVENGDEAYCQPCVSPIWDTGLAGHAMIEAASGPDGIRPHETKKKLA
AAAEWLRSRQILDVKGDWAINCPDVAPGGWAFQYNNDYYPDVDDTAVVGMLLHREGDPAH
HDAIERARQWILGMQSTNGGWGAFDIDNNMDFLNHIPFADHGALLDPPTADVTARCVSFL
AQLGHPEDRPVIERAVAYLRSDQEAEGCWFGRWGTNYIYGTWSVLCALNAAGVSHDDPAI
VRAVDWLRSVQREDGGWGEDCATFEGATPGIYTESLPSQTAWATLGLMAAGLRDDPAVAR
GMAYLARTQKEDGEWDEEPYNAVGFPKVFYLRYHGYRQFFPLMALSRYRNLESSNTRRVA
FGF
>A0A4R5BQC0|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura darangshiensis|TrEMBL
MTTTEVPGLTGAASAAVEAARGHLLGLQSPEGWWKAELETNVTMDAEDLLLRQFLGIRSD
ADTKEAARWIRAQQRDDGTWANFHGGPADLSTTIEAYVALRFAGDPVDAPHMRTAAAFAR
EAGGIEGSRVFTRIWLALFGQWSWDDLPVMPPELMFLPSRVPLNVYDWACWARQTIVPLT
VLGSLRPVRDLPFDLPELRSGVAPPDDATGWGRAFNALDRVLHVYEKAPVRPLRRAALRR
AADWIVARQEADGCWGGIQPPWVYSLMALHELGYGLDHPVIKRGLDGLERFTIRDEKGRR
LEACQSPVWDTVLAMNALGDAGAPADDPALLCAAAWIVGEEVRGPGDWSVRRPDTPPGGW
AFEFDNDVYPDTDDTAEAILALRKVSYPDAEAPIERAIRWLNGMASRDGGFGAFDADNTR
ELCTKLPFCDFGAVIDPPSADVTAHVVEALAKEGLAETTVVKRAVVWLLKAQEADGSWFG
RWGANHVYGTGGVVPALIAAGVGPGKPAIRRAVAWLEEHQNDDGGWGEDLRSYEDPAWIG
RGASTASQTAWALLALLAAGERSPAVDAGVQWLVDNQRPDGNWDEEEFTGTGFPGDFYIN
YHLYRLVFPVSALGRYLGGAT
>A0A1E4QH01|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa NIES-98|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
KRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPVNDPALEKGREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKAVDNFAIQ
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKSVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYSDLKAMIDPNTADVTARVLEMLGTCDVKMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNQYRQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYQALI
>A0A4R6A2L8|squalene-hopene cyclase|EC 5.4.99.17|Rhodococcus qingshengii|TrEMBL
MVNTSKGIDWLVETLRRDQSPDGSWHYPFETGLSTDAYMIILLRTLEINDEELIKGLAER
ILQRQEKNGAWKLFYDEVSGNLTATVESYYALLYSGYFEKQDKRLRAAKKYILSKGGLEE
VSMFTKVMLSITGQMKWPSFSPLPIELILLPLNFPINFYSFSVYGRANLTPMLILTNKKF
TLTTKKRPDLSDLRGGRADSDTWIRSEEIRSLFSFMGKGVKNLMGLPQQLHKLALQRAKK
YMLDHIEKDGTFYSYYSSTFLMIFALLALGYKKNDPVITAAIDGIKAMRTTINGLPHMQY
TTANVWNTSLIGYALQEAGISPEDSMVLKANQYLLARQHDKFGDWVIHNPNSLPGGWGFS
DINTINPDVDDTTASLRSISRMNSTGAWSRGINWLLSMQNNDGGWAAFEKNTDTMLFEFL
PIEKAQFILTDPSCADITGSTLEFFGNYTNLSRDHQSIKKGVNWLLDHQEWDGSWYGRWG
ICYIYGTWGAVTGLTAVGVPSSDASIQKAIHWLHHIQNDDGGWGESCYSDNNETYKPLGA
STLTHTAWALDTLISVSEKPTNEIRKGISFLLKNLDKEDWTTSYPKGQGMAGAFYIHYHS
YRYIFPLLALAHYRKKFEK
>A0A6L7TQ73|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MVTLAKQDLEKRLREALERTQRYFFSTQHEEGYWWGELESNPTMEAEYIMLTRFMGSDEG
ERIPLIAEDIRRRQSPDGSWRMYYGAPGDLSTSVECYFALKLAGDSPEAPHMARARDFIL
RSGGVPKTRVFTKIWLALFGQWDWKGTPAMPPYMMLLPKWAPFNIYRFASWARATIVPMT
IILTLHPTRPPDEGDWIMELYPEGPVTYTLSRWNEKPFSLKGMFLVLDKAIRIYRQLPFI
PGRKAAMKAAVDWIVSHQEADGSWAGIQPPWVYSLIALSALGYSLDHPVISRGLEGFRQN
WSVPSEDGKALRVQACLSPVWDTSLAVRGLLDSGVPPNHSSIERAGAWLIKNEIRIEGDW
AVYNPHLEPSGWAFEFDNVHYPDIDDSAIIATDLASMEFEDEAGERSRLETIKRSVAWLT
GMQCRNGGWAAFDLNNDSRELANIPFADFGELLDPPSVDVTAHVLEMYGHSGYSLDHPAV
RRGLSFVWEQQEHDGPWFGRWGVNYIYGTGAVLPALAALGVDMAQPRIRRAVDWLLAYQN
EDGGWGETCVSYADPTLRGQGDSTPSQTAWALNALIAAGEAGNGLVRRGVEFLLERQLKD
GTWEEPQFTGCGFPGYGPGERPEKFEPLNGPNSQGPELSAAFMIKYDLYRNYFPLSALGR
YARAEHR
>A0A536DUC9|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MMQPTAFGASTSMRPALDEAIRRTQDYFLRTQRADGYWVGELETNVCMAAEYLLLTHFLG
IADDERWRKVVTYLKGRQSADGTWTIYFGGPPDLNATVEAYFALKLAGASPDDPYMRRAR
EFVLSAGGIPRVRVFTKIWLALFGQWDWRGVPALPPELMFLPRWFPLNIYDFASWARATI
VPMLIILTERPICAIPDNARLDELYPQGRKRTPYSLPKPKNMLSWKGFFDAADSVLRSYD
RVAIGPLREAAYRAAERWILARQEADGSWAGIQPPWVYSLIALKLRGYSLDHPAMNKGIE
GFEGAWSIEDGEIFNPQACLSPVWDTALAMIALLDSGLPDGHPALVQAGRWLLREQVLTG
GDWQVRAKGLEPGGWSFEFENDIYPDTDDTAAVMIALARTELPEARKALALERGVHWLRG
MQSANGGWGAFDKDNTRRIVNEIPFCDFGEVIDPPSEDVTAHALEALSLFGEGRSSRPAL
RYLRREQRTDGSWFGRWGVNHIYGTGAVLPALAAAGEDMSRPYVRRAVRWLLARQNHNGG
WGESCSSYVDPSSIGRGPSTASQTAWALLGLLAAGGDSSDGIIAKAVQRGAGYLVETQEE
DGQWLEDEFTGTGFPGDFYIKYHLYRNYWPLMALGRYASRMSPVR
>A0A3N8CKP9|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. Bp9131|TrEMBL
MNDLTEMATLSAGTVPAGLDAAVAGATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELERKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPIAKNPRGVRIDELFIDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AVDGLFPNYTRERAIRQAVSFIDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKALEKLLVVHEDEAYCQPCLSPVWDTSLVAHALLETGDARAEEAVLRGLDWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLRQTDTYRDSMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLI
AQQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A5P2UV60|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces subrutilus|TrEMBL
MERGAQEAAARATRHLLARQDAAGWWKGDLETNVTMDAEDLLLRQFLGIRDEATTRAAAL
FIRGEQQDDGTWSTFHGGPPDLSATIEAYVALRLAGDAPDSPHMARASAWIRAHGGIAAA
RVFTRIWLALFGWWSWDHLPELPPELLFLPPWVPLNIYDFGCWARQTIVPLTVVSALRPV
RPALFALDELHTDARNPHPARRLAPLTSWDGAFQRMDRVLHVYRRHAPRRLRKAAMTAAG
RWIVERQENDGCWGGIQPPAVYSVIALHLLGYDLKHPVMRAGLESLDRFAVWREDGARMV
EACQSPVWDTCLATIALADAGLPPDHPALVKAADWMLGEEIVRSGDWAVRRPGLAPGGWA
FEFHNDTYPDIDDTAEVVLALRRVRHPDRARIEGAIARGVSWNLGMQSKNGAWGAFDADN
TSPLPNKLPFCDFGEVIDPPSADVTAHVVEMLAFEGRAGDPRTRRGIEWLLAEQEPEGGW
FGRWGTNYVYGTGSVVPALTAAGVPTGHPAVRRAVRWLESVQNEDGGWGEDQRSYQDATL
AGKGASTPSQTAWALMALLSAGERDGEAVARGIAHLVGTQHEDGSWDEPYFTGTGFPWDF
SINYHLYRQVFPLTALGRYLYGEPSVRGGEA
>E5AV67|squalene-hopene cyclase|EC 5.4.99.17|Mycetohabitans rhizoxinica (strain DSM 19002 / CIP 109453 / HKI 454)|TrEMBL
MPISAASTCRATRSRQPASCTSRLTRSAPRRSTAPARPWLPTRASTLHKPPRSWHGIRAA
WSLRRASWRKPITRYSRSWSGVALLRRVSACACRVRASCWPLPDTGCSDHAAGPPPAVRR
TAELLRGIRMNMLHEPLNPDVDDARTAHASAPPNERLEQAIRSATNALLDAQHDDGHWLF
ELEADATIPAEYVLMVHYLGETPDPVLEAKIGAYLKRIQGEHGGWPLFHDGAFDMSASVK
AYFALKMIGEPLDAPHMKRARDAILARGGAAKSNVFTRILLALYGILDWRAVPMMPVEIM
LLPTWFPFHLSKVSYWARTVIVPLLVLQAKRPRARNPRGIGIDEIFVGSPRDIGPISKAA
HQSQGWFSFFSTIDALLRKLDPYFPKQSRQKAIDAAVHFVDARLNGEDGLGAIFPAMVNS
VLMYDVLGYPPDHPHRAIARKSIDKLLVIHEHEAYCQPCLSPVWDTALTAHALLETGEPR
AIEHAAKGLDWLLPLQVLDTRGDWISRRATVRPGGWAFQFANPHYPDVDDTAVVAMAMDR
VEKLQVRDRYRNAIDRACEWVVGMQSHNGGWGAFEPENTHLYLNNIPFSDHGALLDPPTV
DVSSRCLSMLAQLPSTPQRQTSASRAKHYILADQEDDGSWYGRWGMNYIYGTWSALCGLR
AAGVAPDTLPLRRAAHWLRSIQNPDGGWGEDGDSYKLDYRGYERAPSTASQTAWALLGLM
AAGCEHDEAVARGIAYLLDTQNDEGLWDETLFTATGFPRVFYLRYHGYRKFFPLWALARY
RNLAVRNACTVACGM
>A0A563E563|squalene-hopene cyclase|EC 5.4.99.17|Leekyejoonella antrihumi|TrEMBL
MTDTATDTSTHASSGSAAQHTLNAALTYLRSLQDEGGWWKGDLETNVTMDAEDMMLREFL
HIATAETREQSARWIRSQQRDDGTWATFAGGPGDLSTTTEAWVALRIAGDKPAAEHMRRA
ADFVQQQGGVERSRVFTRIWLALFGLWDWDDLPNMPPELMLLPKWFPLNIYNWGCWARQT
IVPLTVVCTLRPRRPLPFKIDELRTGAAGPAKQSWRSIGGAFQRLDVALHAYAKHPLMPV
RQGAMRLAAEWILARQEADGGWGGIQPPWVYSLLALHLLGYPLDHPAMKAGVEGLDGFVL
TKETPDGPMRQLEACQSPVWDTALALNAMLDSGVDADDPAIRKASEWLVDEQITVDGDWS
GRTPHLPSGGWAFEFANDNYPDTDDSAIIVMALRRVGSNRPTLLRKAVDRGIAWTAGMQS
RDGGWGAFDANNTHTLANELPFCDFGAVIDPPSADVTAHVVEMLAAEGRARGERCKRGVR
WLLEHQEDDGSWFGRWGANHVYGTGAVVPALIAAGIPTDHQAIRAAVRWLEAHQNTDGGW
GEDLRSYDAPAWIGRGESTPSQTGWALMALVAAGEGSAARAGELTETAVERGIAHLANTQ
REDGGWDEHLFTGTGFPGDFYISYHLYRLVFPIWALGRYLQGGT
>A0A286RG14|squalene-hopene cyclase|EC 5.4.99.17|Thermogutta terrifontis|TrEMBL
MGEALTVARIERALRSVWDLLVARRLPEGFWRGHLCSSPLATATAISALAVYRQNTSDKA
IFSASPGSLDGAISAGLDYLKKTQQKDGGWGDTERSRSNIATTYLVTAAIHLAGQAGYCE
DVLAAAQAYLRSQGELQGLRNRYGADQTFVAPILTNCAIAGIFPWENVPQLPFELAAFPQ
SVYRFLRMPVVSYAIPALVAVGLARHKKCPSSFPPLRLIRDAVQSRCLQVALKMQPNSGG
YLEAIPLTSFVAMCLCTAGLAHHPITARALDFLLRNQRGDGSWPVDVDLATWLTTLAINA
VHAGRPEETASDVPFGSLVSLDWLARCQWLEIHPFTGAAPGGWGWTDQTGAVPDADDTAG
ALLALCHIWPQISAAERARLWPHVILGLHWLVGLQNRDGGWPTFCRGWGRFPFDRSAVDL
TAHAIRALHGWSKVFEHLDAQAEEVQCLDFSERFSPPLRRFIERLWKRRVVFRERLIQAL
NKGMRFLVNCQAEEGFWLPLWFGNEWLPGEANPVYGTAKCLLAFADLDAHNTDCCRRAVC
WLAGNQNPDGSWGWGFWTDNLPTPGQASYRDHSGSIEETALAVAALSALPHQDGLEARSR
GVMWLVRAVEEGKVTQATPIGLYFARLWYFEELYPLIFTLEALGRYLRSATSN
>A0A6G3NUP2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces cyaneofuscatus|TrEMBL
MTATTDGSTGAANLSAAPAGHPADTTTAADGVTAAADDVTAAARRAAERSVAHLLGRQDE
QGWWKGDLATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYGGPSDL
SATIEAYVALRLAGDRPDEPHMARASAWIREQGGIAAARVFTRIWLALFGWWKWDDLPEL
PPELMFFPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPAEPNPPRK
LAPAASWDGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIVERQENDGCWGGIQPPAVY
SIIALHLLGYDLDHPVMKAGLASLDRFAVHREDGARMVEACQSPVWDTCLATIALVDGGL
RPDHPALVKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALR
RVRHPDPARLEAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSA
DVTGHVVEMLAVEGLGAHPRTRRGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALVAA
GLPAAHPSIRRAVTWLESVQNDDGGWGEDLRSYTEEKWIGHGESTASQTAWALLALLAAG
RRDSRAVARGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYG
DPFADRTGAAQGA
>A0A7C3EK76|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MRSWPKLGAQAHGAQNSLGAAAGGPSCACARRTDLNSYNTLNGRACKRLLSTGPLLQEVR
MNDMLQNSLLPTATLEESSAGWETKLDEAIRRTQAFLLRRQQADGYWHFPLEANVTMDAE
YIFFNRFMGRDARRQEARVVDHMFSTQAPDGSWSLYPGAPGHVSLTIEAYFALKLAGISP
QEERLQQAARFIRAHGGLAKAGVFTRCFLAYFGQFPWYGLPAMPVELILLPPWFPINIYA
FSSWARETVVPLTILMALKPQVPLAPGEGVDELWLSPPTPQALAFPGSREWISWKNFFLA
VDSTLKFLSRTIPWAPLRQRALRRAEQWILERQDRNGGWGGIQPPMLNCVMALKTLGYPD
DHPVIRKGIQAIDDFLIADGDSLMMQPCVSPTWDTALGAKALLDSGLSPDHPALARAAEW
LIRNQIFKPGDWSVYNPDLDPGGWAFEFANDWYPDVDDTAVILMQLQRIAIKDRHARQRA
IAYGLQWALGMQSRNGGWAAFDTNNDSEFLNQIPFADMEAMIDPPTEDLTGRLLELMGNY
GFDLQSSRARKAHRFLLRTQRSDGSWWGRWGANFIYGTWSVLAGLRAIHDDLHAPHIRRA
VAWLKQHQNSDGGWGETLASYDNEALAGRGESTPSQTAWAILGLLAGEDGVSREVLRGVE
YLVRTQNPDGSWDERLWTGTGFPRHFYLRYDGYRIYFPLMALGQVRQRLRELRGARARTA
AESAVHSR
>A0A432MG79|squalene-hopene cyclase|EC 5.4.99.17|Tautonia sociabilis|TrEMBL
MIVKLDGGKLGRGADTDASSRIDRSPSIAPEDLDLGLSATRRWLLDRQRDDGHWVGELEG
DTILESEFVLLLAALGREDEEVAVKLCTYLFEQRLPEGGWAIYPGGPFDLSASVKAYFAL
KLVGVPPDHPVMARVRELILEAGGAQASNSYTRFYLALLGQMSYDDCPYVPPELLFVPIR
SGLSLYDMSSWTRTMVVPLSILSVQRPVRHLPAEKGIAELFRPDLPPPSRGTGRGLSWAN
VFVAVDRCFKWAHRIVPRALRRPGLEAAHRWMVDHFERSEGLGAIFPAMVYSVFALRSLG
YEDDHPLIRRAMAQLEDLMIEEDGAVRVQPCVSPTWDTAIATIALADSGVPADDPAMTGA
ARWLLDREIRTPGDWQLRRPGLEATGWAFEYRNDHYPDIDDTAMVLLALGRTALAGGPEG
RAATDRAIAWLLAMQNRDGGWAAFDVDIDNQLLTKVPFADHNAILDPSCADITARILEIL
GSLGYKADHPAVARGLEYLWATQEPEGCWYGRWGVNYIYGTWQVLLGLQAIGLPMSHPAV
QRAADWLESVQQEDGGWGESCRSYEDPAWMGRGVTTASQTAWAVNGLIAAGRAHGASVRR
GVSFLLRTQNPDGTWDEPQFTGTGFPKVFYLRYHLYRIYFPLMALSRYRAAVSGSWSARA
GRAAPRTGALACGVPADPRPLEA
>A0A534TBI1|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MVRGAEPAPAARRVVIGARTRIERSGLDLVIERAQGWFERQQYPEGYWWAELESNATMDA
EYLLLTHFLGARNEDLWRGVAQDIRNYQRDDGSWAMYHGAPGDVSTSIECYFALKLAGDR
PDAPHLVRARAFIRERGGIARARTFTRIWLALFGQWSWDDLPIMPPELMLLPPSAPLSIY
RFSSWARGTIVPLLLLMDDRPVHPVPDSARLDELRVADAAPRVPRDAIDRLFRGIDGALR
AYDRLPFHPFRERARKAAEQWILAHQEADGSWGGIQPPWVYSLMALHALGHPLDHPALKN
GLLGMHGRWMLRHGDGRLRVQACLSPVWDTGLSLLALVESGAHPSVPMVQQAARWLLREE
IRVPGDWCVQVEGVEPSGWAFEFENDLYPDVDDTAVVLLALHKADALDAETRERALRWVL
AMQSRNGGWAAFDKDNTSRLPALIPFADFGEMIDPPSADVTGHVVETLGAFGLARSHPAM
ERGLRYLYAHQEKEGSWFGRWGVNHVYGTGAVLPGLAAAGEAMDGLAVRRAVRWLGERQN
PDGGWGETCASYVDVKARGRGDSTASQTAWALLGLIAAGRADGKAASRGAHFLVDRQRPD
GSWDEESFTGCGFPGYGIGEEHGARIVEGRELSAGFMIRYHLYRNCFPLLALGRYRAALG
GAGAIRSEGGS
>A0A840MY52|squalene-hopene cyclase|EC 5.4.99.17|Afipia massiliensis|TrEMBL
MTLLDDHKAAVAPTAPALESSIAAASRAILDTRKPDGHWVFELEADATIPAEYVLLRHYL
AEPVDAVLEAKIGNYLRRIQNENGGWSLFYGHEFDMSASVKAYFALKMIGDSVDAPHMKK
ACEEMLRRGGAIKSNVFTRIMLALFGVVTWRAAPMMPVEIMLLPRWFPIHLTKISYWART
VIVPLLVLMNKKPRARNPLGVGIDELFLEDPKSIGMTAKAPHQSQLWFTGFSILDAVLRV
VDPLFPKKSRQHAIDKAVAFVTERLNGVDGLGAIFPAMANTVMMYDLLGYPKDHPHYVLA
RQSVENLLVIKDDEAYCQPCVSPIWDTALAAHAMIEVGGEKAEASAKAALDWLKPKQVLD
VEGDWIEKRPGVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRARGTLQAGTKYDEAIARGR
EWLLGLQSKDGGWAAFDADNLEYYLNNIPFSDHGALLDPPTEDVTARCVSMLAQLGETAK
TSEALARGIEYLRRTQLPDGSWFGRWGVNYIYGTWSVLCALNAAGVDHNDPVMAKGADWL
ISIQNSDGGWGEDGNSYRLDYKGYVKSETTASQTAWATLALMAAGKVDHPATQRGIAYLI
QNQTRDGLWTEPQYTGGGFPRVFYLRYHGYSKFFPLWALARYRNLRNTNSRFVGIGM
>A0A534NDB0|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MVRGARPARATRRLVIGSESRIERSGIDLVIERAQGWFEREQYPEGYWWAELESNATMDA
EYLLLTHFLGARNEEHWRGVAQDIRSYQRDDGSWAMYHGAPGDLSTSIECYFALKLAGDP
ADGPHLARARAFIRERGGIARARTFTRIWLALFGQWSWDELPVMPPELMLLPASAPFSIY
RFSSWARGTIVPLLLLMNDRPVRPVPAAARLDELRVPEAAPRPPRDAIDRLFRAIDTALR
GYRRLPFHPFRQRARKAAEQWILAHQEADGSWGGIQPPWVYSLMALSALGHPLDHPALGK
GLEGMHDRWMLRHADGRVRVQACLSPVWDTGLSLLALLESGVDPSASMVERAARWLLREE
IRVPGDWCVQVQGVEPSGWAFEFENDLYPDIDDTAVVLLALLKAGAVDAQLRERALGWVL
AMQSRNGGWAAFDKDNTSRLPALIPFADFGEMIDPPSADVTGHVIEMLGAFGVGRDHPAI
QRGLRYLYAQQEKEGSWFGRWGVNHLYGTGAVLPGFAAAGEAMDGLAVRRAVRWLSERQN
ADGGWGETCASYVEIEARGRGESTPSQTAWTLLGLIAAGRADSKAASRGVHFLVDRQRSD
GAWDEESFTGCGFPGYGIGEEHGARIVEGRELSAGFMIRYHLYRNCFPLLALGRYRAALR
GTARAIPSEGGS
>A0A534X1P5|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MVRGAGSARAARRFVIGTGIAVERSGIDLVIERAQGWFEREQYAEGYWWAELESNATMDA
EYLLLTHFLGARDEEHWRGVAQDIRNYQRDDGSWAMYHGAPGDLSTSIECYFALKLAGDS
PEAPHLARARQFIRERGGIARARTFTRIWLALFGQWSWDDLPVMPPELMLLPASAPFSIY
RFSSWARGTLVPLLLLMNDRPVRPVPDSARLHELRVPGAAPRAPRDAIDRLFRAIDAALR
GYRRLPFHPFRQRARKAAEQWILAHQEADGSWGGIQPPWVYSLMALRALGHSLDHPALRK
GLDGMHDRWMLRHGDGRVRVQACLSPVWDTGLSLLALLDSGVEPSAPLVQRAARWLLREE
IRVPGDWCVQVQGVEPSGWAFEFENDLYPDVDDTAVVLLALLKAGAVDFPLRERALRWVL
AMQSRNGGWAAFDKDNTSRLPALIPFADFGEMIDPPSADVTGHVVEMLGAFGVGRSHPAM
QRGLRYLYAQQEKEGSWFGRWGVNHVYGTGAVLPGLAAAGEAMDSLAVRRSVRWLSERQN
ADGGWGETCASYVDVEARGRGESTPSQTAWALLGLVAAGRADSKAANRGAHFLVDRQRSD
GAWDEESFTGCGFPGYGIGEEHGARIVEGRELSAGFMIRYHLYRNCFPLLALGRYRAALR
GTARAIPSEGGS
>A0A8D9R6D8|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia mallei FMH|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANAMRVTVGM
>T2AZB9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLAMHAVLEANSVPDKIIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVVDTAVVVMALHRADSAHYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWYGRWG
>T2B010|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIIIEKAANWLVERQILDVIGDWAANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADPDHYSEAIARGAEWIIGMQSGNGGWDAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARSIVYLKRGQEVNGSWFGRWG
>T2AZA9|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWFGSWG
>T2B0A0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWAANAPGVRPGGWAFQY
WNDYYPDVDDTAVVVMALRRADSARYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGSDNQAVARAIGYLKRGQEVNGSWYGRWG
>T2B069|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGAPLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWFGRWG
>T2AYA4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTRLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDFYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWFGRWG
>T2AZ38|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPSADQGALLDPPTVDVTGRAITLLSLADKKIYANNIKGGVDYIKSEQEEDGSWYGRW
G
>T2AYE3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINNGVNYIKSEQEEDGSWFGSW
G
>T2B0C5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSEEPGDWRIQKPELIGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPFADHGALLDPPTADVTGRAIAFLVL
>T2AZX7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLAALALQEANPKATRHSREKAYNWLKTKQLDKQPGDWQIQQPHLNGGGWAFQF
ENPHYPDVDDTAVVAFAMANACDLNNLEESIHRATHWTAGMQSKNGGFGAFDCDNTDYYL
NHIPFADHGALLGPPTADVSARCAMLLGHQLSSHPEYQKTLDKTITFLRKEQESDGSWYG
SW
>T2B017|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAIAANALLDSGLPSDHPALIKAGEWIIRKQVVKRGDWQVKIPGAEPGGWAFEFY
NELYPDTDDSAEILIFLSRVDIPNNRWKLSECGRAMDWLLSMQGKKGGWGAFDVDNDKEL
LNKIPFADHKALLDPPTADVTSRILWMLAKWGFKKQHPQVQRAIQFVKENQEIDGCWYGR
WG
>T2B0A1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTCIAQLAPLESGIDPEDPMVQSSARWLMDKQIYAAADWQVRAKGTRPGGWSFEFD
NLIYPDIDDASIVVMALDQVRLPEAEEPRRADSIQRGVEWMAGMQSKNGGWAAFDKDNNK
KYLTKIPFSDFGETLDPPSVDVTAHLLEMYGRLGYTKEDRAVGRGFAYVISEQEEDGSWY
GSWG
>T2AYP5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLNGLSLLESGLTLKDPAIQKACKWLEKKQILKINGDWAVKNKNLVPGGWAFQY
ENDFYPDVDDTAVVAMFPDRAGYQNKKNIEKACNWIVGMQSNNGGWGAFDKDNTSYYLNN
IPFADHGALLDPPTADVSARCVSMLSQIDKNSYKNTIKKGIEFLKNEQEEGGSWYGRWG
>T2AZL7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGFNGLSLLESGLTLKDSSIQKACKWLEKKQILEIKGDWIVNNKNLLPGGWAFQY
ENDFYPDVDDTAVIVMFLDRAGYQNKKRLEIACNWIIGMQSKNGGWGAFDKDNTYHYLNN
IPFAVHGALLDPPTADVSARCISMLSQINKKNYKKIIQKGVKFLKNEQENDGSWYGRWG
>T2B060|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTALVSQALIEIEYKQHVSTEIETALNWLKEQQLNEEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKRYSEPIQRAANWVAGMQSRGGGFSSFGINNTHFYL
NEIPSADHGALLDPPTADVTGRAITLLSLADKKIYEKNIKDGVDYIKSEQEEDGSWYGR
>T2AYZ0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTGLAVHAMLEAGEPKNGARLNKAMRWMADRQVCDVSGDWATHRPGLRFGGWAFQY
ANDHYPDVDDSAVVAMALDRASDPKVKQGLPRAVEWIVGMQSKNGGWGSFDAGNSHYHLN
HIPFADHGALLDPPTEDVTARCVGMLAQIGDEAGNDAIERGLSYLHETQQPDGSWYGRWG
>T2B041|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTALVSQALIETEYKQPVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKNYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAIVLLSLTDKKIYEKNIKDGINYIKAEQEEDGSWYGSW
G
>T2AYR1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTAICSNALLDSGLPTDHPALVRAGKWIVSKQVTKRGDWQVKNPKAEPGGWAFEFY
NELYPDTDDTAEILLFLNRVEIPDNRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGKWGFNKQHPQVKRAIKFVKERQEIDGCWYGR
WG
>T2B063|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
WDTALVSQALIETEYKQHVSTEIEAALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQYSN
YYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYLNEI
PSADHGALLDPPTVDVTGRAIALLILADKKIYEKNIKDGINYIKSEQEEDGSWFGRWG
>T2B006|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGFNGLSLLESGLTLKDSSIQKACKWLEKKQILEIKGDWIVNNKNLLPGGWAFQY
ENDFYPDVDDTAVIVMFLDRAGYQNKKRLEIACNWIIGMQSKNGGWGAFDKDNTYHYLNN
IPFADHGALLDPPTADVSARCISMLSQINKKNYKKIIQKGVKFLKNEQENDGSWYGRWG
>T2B079|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAFVIQGLLEEGSKKYKSKINKGMKWLEQKEIKNIRGDWSEKRPKLKSGGWAFQY
ENPFYPDLDDTALVGMIFHRQDPKSKNTIIKRTAEWVAGMQSKNGGWGSFDADNTNYYLN
HIPFADHGALLDPPTADVTARCISFLSQIGYKKNEAITKGINFLKQEQEQNGSW
>T2AXX3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIEAALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRSGGFSSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAITLLSLADKKIY
>A0A553KT75|squalene-hopene cyclase|EC 5.4.99.17|Brevibacillus sp. LEMMJ03|TrEMBL
MPLRVNSELERLTAVLQREQQADGSWRYCFESGPLTDAYAIILLRTLNIPNEPLISGLAK
RIASRQAPDGTWKLYPDERDGNLSTTIESYFALLAAGAAAPSDERLQAARRFIRAKGGLA
QANLGTRVMLALTGQHPWPPFPIPAEFMLVPPFFPLHLFDLVGFARVHLVPIMVAAARTF
AVRSRQMPDLSDLFRGLPSAGPQQPDLIWFHELIDSGIRSLPSFLRPARELGLREAERFL
LDRLEPDGTLYSFFTATFLMIFALLALGYRPDHPVIIRAVRGAERLVCPVGDVLHMQNST
STIWDTALLSHALQTAGMPVSHPVIQQATRYLLSRQHNRYGDWARRSPGVPPGGWGFSDI
NTINPDVDDTTAALRALHRAGRGDPAIRQAWDRGLRWLLSMQNSDGGWPAFERNTANPLV
KLIPAGGAEAAFTDPSTADLTGRTLEFLGNHAGMTLQHPAVRRGVDWLLRHQEANGSWHG
RWGISYLYGTWAALSGLIAAGVSPDHPAIQKGVSWLRSVQNRDGGWGESCQSDVLKRYVP
LGASTPSQTAWAVDALTAVSRRPGPELEAGVRFLLAAGKRRDWTSSYPTGAALPGGFYIH
YHSYRYIWPLLALAQYRNKFQP
>A0A2U3Q5G4|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium vignae|TrEMBL
MDSVNATSREALESSIASATQGVLDFQQADGHWVFELEADCTIPAEYILLRHYLGEPVDA
VLEAKIGNYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDSVDAPHMVRAREAIH
ARGGAIHSNVFTRFLLATFGVVTWRAVPVLPVEIVLLPFWSPFHLNKISYWARTTMVPLM
VIAALKPRAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFLLFRSLDAILRVIEPMFP
KSLRKRAIDAALAFIEERLNGEDGMGAIYPPMANIVMMYDALGKDENYPPRAITRRGLDK
LLVIGDEEAYCQPCVSPVWDTTLTAHALLEAGGDKAVPAAKQGLDWLIPKQELEVKGDWA
VKRPDVRPGGWAFQYNNAHYPDLDDTAVVVMSMDRMRREHGVAGYDAAIARGREWIEGMQ
SDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETVKTSKHVAD
GVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVDHKDPMIRKAAAWLTSIQNDD
GGWGEDAVSYRLDYKGWESAPSTASQTAWALLALMAAGEVDHPAVARGVEYLIATQNKKG
LWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRVVGVGM
>Q0B5S3|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia ambifaria (strain ATCC BAA-244 / AMMD)|TrEMBL
MNDLTEMATLSAGTVPAGLDAAVASATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGRYLRRVQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIQAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPIAKNPRGVRIDELFVDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AADGLFPNYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKSIEKLLVVQEDEAYCQPCLSPVWDTSLAAHALLETGDARAEEAVIRGLEWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANPHYPDVDDTAVVAVAMDRVQKLKHNDAFRDSIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCALNAAGLTPDDPRVKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGVEYLI
AEQKEHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRNNATRVTFGL
>T2AZZ0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSEPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRSDPDRYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQMGYGPDNQAVARAIRYLKRGQEANGSWFGSWG
>T2AYL4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAICSNALLDSGLPTDHPALVRAGKWIVSKQVTKRGDWQVKNPKAEPGGWAFEFY
NELYPDTDDTAEILLFLNRVEIPDNRWKLSECQRAMDWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGKWGFNKQHPQVKRAIKFVKERQEIDGCWYGR
WG
>G4T320|squalene-hopene cyclase|EC 5.4.99.17|Methylotuvimicrobium alcaliphilum (strain DSM 19304 / NCIMB 14124 / VKM B-2133 / 20Z)|TrEMBL
MFTDATTEINTRDLPSSATAIVAKPNDLNKTISKAQDYLLKLQQPDGHWIFELEADCTIP
SEYIMMMHYLGEIDEGLQAKIANYLRSRQSEDGSYPLFTGGPGDISGSVKVYYALKMAGD
SIDAPHMQKLRNYILSQGGAARANVFTRIALAMFEQLPWRGVPYIPVEIMLLPKWFPFHL
DKVSYWSRTVMVPLFVLCSEKATAKNPNKVDILELFVVHPDKEKHYFPERTALNKFFLML
DKLGRVTRPLIPQSMHRKALDRAQDWFIERLNGEDGLGGIFPAMVNAYEAMLLLGMPKDH
ELVVTARKAIDKLLVINEHDAYCQPCLSPVWDTGLTALALQEVDKNGNRDALIRAYDWLK
SKQLIDEPGDWQVTKPDLEGGGWAFQYANPHYPDVDDTGLVAFAMADSNLPELDESIHRA
TRWIVGMQSENGGYGAFDVDNTYYYLNEIPFADHGALLDPPTVDVTARCAMLMARVAKGH
DEYRPALQRTIDYIRSEQEADGSWFGRWGTNYIYGTWSVLLGLEQTDVPKTDPMYVNAAR
WLKSVQREDGGWGEDNFSYHDEQNFRGKYRFSTAFQTAWAIIGLIAAGEAHSPEVKAGVE
FLMKTQLTDGSWNDKCFTAPGFPRVFYLKYHGYDKFFPLWALAKYRNAINNS
>A3NPJ5|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia pseudomallei (strain 668)|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A4R5LL65|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia guartelaensis|TrEMBL
MKNSNPPFTASAAAVAALDASIVRGREALVREQDADGSWCFELESDATITAEYILMMHFM
GKIDVVRQEKMARYLRAIQRLQTHGAWDLYVDGAPDVSCSVKAYFALKAAGDSENALHMM
RARDTILKLGGAAKSNVFTRILLATFGQVPWRATPFMPIEFVLFPKWVPISLYKVAYWAR
TTMVPLLALCSLKARAANPHDVSIAELFVKPPEEEREYFARGKGIRRFFLAADRALRHIE
PLLPRALRQRAMKYAEAWCAERMNGEDGMGGIFPPIVYSYQMMQVLGYPEDHPLRRDCEN
ALEKLLVERPDGSVYCQPCLSPVWDTAWSTMALEQARTVVPADPASAAISDQELQRRITR
AYDWLAERQVDDVRGDWIENAQPDTPVGGWAFQYENPYYPDIDDTAVVAAMLHRRGLGEA
RKTGVDPYAARVTRALDWMRGLQSRNGGFGAFDADCDRLYLNAIPFADHGALLDPPTEDV
SGRVLLCFGVTGREEDKAALARAIEYVKATQQADGSWWGRWGTNYIYGTWSVLAGLALAG
EDPKQPYIARALAWLRARQHADGGWGETNDSYIDPRLAGTNGGESASNFTAWALLAQMAF
GDWESESVRRGVAYLLSVQQEDGFWWHRSHNAPGFPRIYYLKYHGYTAYFPLWALSRYRR
LAGGTVVAREVEEAALAD
>A0A538LAF5|squalene-hopene cyclase|EC 5.4.99.17|Actinomycetia bacterium|TrEMBL
MSATEQLTALDAAIDRGTRRLLELQRPDGIWVGELESNVTMTAQHLFWNHALGLRTPDLD
RRIANELTARMRDDGTWSIWFEGPPDLSTSVEAYVALRMCGVDPGLKAKAYIRSQGGIPK
SRLFTKCFLALLGQWPWQRMVPIPPELVLLPPSAPFSIYNFACWARQTFVALALAQSLRP
VRPADVDLRDIGAIPGRTRRPLRRDPLRRLAQRRAEEWIRARQEADGSWGGIQPPWVWGI
IALHALGHGFDDPTLRKAVEGWDGFMVEDGDRLRPEACQSPVWDTALAVLALRACGVPSD
HPQLVAAGAYLLREEVTVKGDWAIRRPALAPGGWAFEYENDLYPDVDDAAVVALALHELG
IGGDAIDRSLDWLVGMQSSDGGWGAFDVDNSAMWLYKIPFCDFGKVTDEPSADVTAHTLE
TFGTLGARADSSARGVEWLLAEQEADGSWFGRWGVNHLYGTGAALPGLAACDIPADHPAM
RRAVAWLDSVQQENGGFGEDIRSYSDPDWRGRAPFTTPSQTAWALLGYVAAGNAEDHGAR
KAADYLCAVQRPDGDWDEEHFTGTGFPLDFMIRYHLYRINFPLLALGRLRERLST
>A0A7Y0Q1Q2|squalene-hopene cyclase|EC 5.4.99.17|Sulfobacillus sp. DSM 109850|TrEMBL
MSITGAVVEDRVSRALEAAKDHLLRLQREEGYWWGDLITNVCMEAEYVMLLHILEKRWPE
REEQVRRYILSTQNDNGSWSIYWGQGGDLNATIEAYQALKMTGQDPESEPMTKARNYIRE
QGGIEKSRVFTRFWLALLGQYDWEDLPILPPEIMWFSPKAKRSIWDFGSWARPTVVALAI
LMAKRPVFPLPPEQRVIELERGVRPEPRIEGPASFYYRLDRWLHWYHRRGWHPGRERAVE
SAFQWLVDRQERDGSWGGIQPPWFYSLIVFKVLNRTDHPAFKKGFEGLEGFGVSDDGRWW
FQACVSPTWDTGLAVLALRAAGVPASHPALVQAGQWLLDQQVLEVRGDWAVRRPKVKPGG
WPFEFANDTYPDIDDTAIVLMALNQLDLPDDARRKRALTKGFRWMVGLQSQNGGWGAFDA
DNVKTWVSEIPFSDFGWVNDPPTEDVTGHVLESLGQFGYDDAWPVIDRAVKFLKERQEPD
GAFFGRWGVNYIYGAGAVLPGLQAIQYDLSEPWVQKCLDWVEAHQNDDGGWGEVCDSYVD
SSLRGTGPSTASQTAWATMALIAGGRHQQYSVQRGVAYLVAQQKGDGGWDEPQYTGTGFP
KDFYINYALYRDIFPVLALARYQKALRGGQR
>A0A7W9LCY0|squalene-hopene cyclase|EC 5.4.99.17|Nonomuraea jabiensis|TrEMBL
MTTLETTPSLLTDAEQALRAACDHLIGLRSPEGWWKGELQTNVSMDAEDLLLRQFLGIRT
EQDTAEAARWIRSEQRADGTWANFHEGPAELSTTVEAYTALRLAGDPPDAEHMRAASEQV
RAMGGIEASRVFTRIWLALFGEWSWRDLPVMPPEMIFLPSWFPLNVYDWACWARQTIVPL
TVVTAYRPVRGLPFQLPELRTGRAPHRAAGGGWEAAFGALDRALHRYERRPSRALRRAAL
RRAVGWVVARQEADGSWGGIQPPWVYSIIALHLSGYDLDHPVMRKAIGGLDRFTVRDEKG
RRLEACQSPVWDTALAINALLDAGTPADHPAVTGAADWLLREEVTRTGDWAVRRPGLPPG
GWAFEFDNDGYPDIDDTAEVVLALRRLERPGARPAIERGVRWMAGMASADGGFAAFDADN
DRALCTKLPFCDFGAVIDPPSADVTAHVVEALAKERPGSAVLRRAVIWLLRAQEEDGSWF
GRWGANHVYGTGAAVPALVAAGVRPGHASVRRAVAWLERHQNDDGGWGEDLRSYRDPAWI
GRGASTASQTAWALLALLAAGERSPAVERGVRWLVDRQRPDGTWDEPYFTGTGFPGDFYI
NYHLYRLVFPISALGRYLRREEELS
>Q3JIF6|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia pseudomallei (strain 1710b)|TrEMBL
MHTLDATAAPAGLDAAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHYLGEAPN
VELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQRARRAI
HAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWARTVIVPL
LVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLRLVDGLF
PRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAIARRSIE
KLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQILDVRGDW
ISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAREWVVGM
QSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSASSEPAR
RALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWLLSIQNA
DGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDNPAVARGVDYLLGTQREH
GLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A7C2IAI3|squalene-hopene cyclase|EC 5.4.99.17|candidate division NC10 bacterium|TrEMBL
MEAALEGAIHEVVEILLRQQDPAGFWVHELEADATITSEYLLLRRWLGIADPAAEAKAVR
HLQGIQLPDGGWPIYHNGPANLSASVKAYFALKMAGVSPEAPEMRRARQAVRELGGITKV
NVFTRILLALFGEFDWRGVPCMPVEICLLPRWFYFNLYQISYWSRTVLVPLLIIFAHRPV
RPVPRSARLDELYLVPREQADYALPRDPETFTWRNLFLVVDRLLRIQDRLVPRAFRRPAI
EAATRWMLERMQGEGGLGGIFPAMANSVIALTCLGYPVDHPAVRKALAEIDALRIETADS
LRVQPCLSPVWDTALSINALIEAGLPPDHPALSRAGTWLLANQARRSGDWRLKSPGTEPG
GWTFQFDNEFYPDVDDTAVVLMALRKIRVVDEEAKTRAIARGLNWLLALQGSDGGWGAYD
KDNNRMVFNRIPFADHGALMDPSTEDLAGRVLEALGYLGFRPDEPAAAKALAFLKARQCW
DGSWYGRWGVNYVYGTWSVLAGLASIGEDMEAPYVRRAVAWLLSRQNPDGGWGESCYTYD
DSRTAGMGKSTASQTAWALMALLQAGEAGSPAVARGIRFLLETRAPHGLWDEREFTGTGF
PRVFYLRYHGYARYFPLWALALYRRSQRTSVVRPASVARLRPADLLR
>A0A427NI86|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia cenocepacia|TrEMBL
MNDLTEMATLSAGAVPAGVDTAVARATDALLAAQQADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKALEKLLVVHDDEAYCQPCLSPVWDTSLVAHALLETGDARAEEAVLRGLEWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLKQSDTYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRAAQWL
LSIQNKDGGWGEDGDSYKLNYRGYEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLV
AQQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
>A0A5N9G3Q0|squalene-hopene cyclase|EC 5.4.99.17|SAR202 cluster bacterium|TrEMBL
MLPNRKEVDRVRSTSGMDSPVQIVRAPVDGLDHAVRNASAHLLSMQYPEGYWWGELESNP
TMEAEFLLLTRFLGIDDEETWRKLTNHLLEQQRPDGTWGQFYGAPGDLSTSTECYFALKL
AGVSPERESMKKAREFILSKGGVPETRVFTKIWLSLFGQYEWRGVPSMPAEFMLLPNWFP
ITIYDFSSWARATVVPLLVILDRKPVKSVPDSAAIDELYPLPRDRTDYSIKRPARLIGWE
TFFYAGDIVLRHLERSPWKPARSQAIAKAERWILAHQEADGSWGGIQPPWVYSLMALEVL
GYPLDHPVMQKGVQGFTSFSIEDNDRLRVQACVSPLWDTCLTMIALLDGDVDPSHPALLR
ASDWLSGQQILTGGDWQVKAKGVSPGGWAFEFHNDLYPDLDDTSEIVMALDRVAVPDDDK
QRRAIERAVRWLLGMQSHNGGWAAFDKDNTNVLMAKIPFSDFGETIDPPSVDVTAHILEM
LGQLGYTAEHPAVSAGLEYIRSEQEPDGPWFGRWGVNYVYGAGAVLPALRALGEDMEADY
VRMAVDWLRDHQNDDGGWGESCVSYVDPDYKGRGPSTASQTAWALLALLAAGEVDDSSTR
SGVEYLLRTQLADGAWDEPYFTGTGFPGYGVGQKTADGGDAEAYRSHELPAGFMINYHMY
RYCWPLMALGRYKRLIAGEPWPADRERNDTSDDAWVGHAKRPANRLHRFLKIW
>A0A7D3VQZ8|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura verrucosospora|TrEMBL
MTTTEAPGLTGAAAAAVEAARDHLLGLQSAEGWWKAELETNVTMDAEDLLLRQFLGIRTG
AETAAAARWIRSRQRADGTWANFHGGPPDPSTTIEAYVALRLAGDPPDAPHMRKAAAYAL
EAGGIEGSRVFTRIWLALFGQWSWDDLPVMPPELMFLPSRVPLNVYSWACWARQTIVPLT
VLGSLRPVRSLPFDLPELRAGRRPARKATGWGRAFNTLDRVLHVYEKAPVRPLRTAALRR
AAEWIVARQEADGCWGGIQPPWVYSLMALSLLGYDLDHPVMKRGLAGLDRFTIEDEKGRR
LEACQSPVWDTVLAMNALSDAGAPAGDPALLRAARWIVDEEIRGPGDWSVRRPDLPPGGW
AFEFDNDLYPDTDDTAEAILALRRSGLPEARGPIDRAVRWMSGMASKDGGFAAFDADNTQ
ELCTKLPFCDFGAVIDPPSADVTAHVVEALAKEGHAESPVTKRAVVWLLKAQEADGSWFG
RWGANHVYGTGGVVPALIAAGVRPDKPPIRRAVAWLEHHQNPDGGWGEDLRSYDDPAWIG
RGTSTPSQTAWALLALLAAGERSPAVEAGVRWLVDHQRPDGTWDEDQFTGTGFPGDFYIN
YHLYRLVFPISALGRYLGRDR
>A0A6N8SUV1|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia sp. 4701|TrEMBL
MNDLTDMPTLSAATVSAELETAVQRATDALLAAQQPDGHWVYELEADSTIPAEYILLVHY
LGETPNLELEQKIGRYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARKAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPIAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANSVMMYAALGYAEDHPNRAI
ARESVEKLLVVKDDEAYCQPCLSPVWDTSLAAHALLETEDPRAEEAVVRGLEWLRPLQIL
DVRGDWISRRPNVRPGGWAFQYANPHYPDVDDTAVVVMAMDRVEKLKHSDAYRESISRAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETAA
NSEAARRSLDYMLKEQEPDGSWYGRWGMNFVYGTWTALCSLNAAGLGPEDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLDYRGYEQAPSTASQTAWALLGLMAAGEVNNPAVARGIDYLV
AEQQEHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNATRVTVGM
>A0A367HUQ8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SDr-06|TrEMBL
MTATTDGSTGAPRPRAAAARRTTGTAAGPEAVLDAARRAAERGVEHLLARQDAQGWWKGD
LETNVTMDAEDLLLRQFLGVQDEKTLHAAALYIRGEQRDDGTWATFYGGPGELSTTVEAY
VALRLAGDRPEDAHMARASAWIRANGGIAACRVFTRIWLALFGWWKWDDLPELPPELIFL
PKWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDARHPNPAKPLAPVASW
DGAFQRLDKVLHAYHKVAPRKLRRAAMRSAARWIIERQENDGCWGGIQPPAVYSVIALHL
LGYDLQHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLAAIALADAGVPADHPAL
VRAADWMLGEEITRPGDWAVRRPQLAPGGWAFEFHNDNYPDIDDTAEVILALRRVKHPQQ
DKVEAAIARGVRWNLGMQSKNGAWGAFDADNTSAFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAYEGRAHDPRTRRGIEWLLAEQEANGAWFGRWGVNYVYGTGSVVPALIAAGIPSAHP
AIRRAVGWLESVQNDDGGWGEDLRSYGETEWMGRGPSTASQTAWALLALLAAGERDGRAA
ERGIAWLAENQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFSLNS
TKGS
>A0A401M634|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. NL15-2K|TrEMBL
MSREDEHRPTADPQQTHTTCTLHEGEAMTATTDGSTGALPPRAAAASESDSTPVAAGVHD
AAVRAVKRATDFLLARQDAQGWWKGDLETNVTMDAEDLLLRQFLGIRDEKTTQAAALFIR
GEQREDGPWATFYGGPGELSATIEAYVALRLAGDAPDAPHMAKASAWIRGQGGIAASRVF
TRIWLALFGWWKWEDLPELPPELIYFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPA
PFPLDELHTDPNRPNPPKPLAPVASWDGALQRLDKALHALRKVAPRKLRGAAMNSAARWI
IERQENDGCWGGIQPPAVYSVIALHLLGYDLEHPVMRAGLQSLDRFAVWREDGARMIEAC
QSPVWDTCLAAIALADAGVPADHPQLVRAADWMLGEQIVRPGDWSVRRPQLPPGGWAFEF
HNDNYPDIDDTAEVVLALRRIKHHAPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSP
FPNRLPFCDFGEVIDPPSADVTAHVVEMLAVEGLSHDPRTRRGIEWLLAEQEPDGSWFGR
WGVNYVYGTGSVVPALTAAGIPGSHPAIRRAVAWLESVQNDDGGWGEDLRSYKYVKEWSG
RGASTASQTAWALMALLAAGEKDSPAVERGIEWLASTQREDGSWDEPYFTGTGFPWDFSI
NYHLYRQVFPLTALGRYVHGEPFSGAKGG
>A0A534DA75|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MNRGSPTRGSFAVTPHAARADAPAHKIHRLAEFSPLDRTIAAARDALISLQSPQGYWLFE
LEADCTIPAEYVLMTHFLEEIDAPLEAKLAAYLRARQAEHGGWPLYHGGDFDMSCTVKAY
FALKLAGDSPQAPHMVRARAAILQRGGAARCNVFTRITLALFGQIPWRAVPYMPVEIVLL
PRWFPFHLDKVSYWSRTVMVPLLILCTRKPAARNPRNVQIRELFTTPPEEERHYFRRPGG
REGVLSRAFLALDRLGRMIDPLVPKAVRAYATRRAEAWMLERLNGEDGLGAIFPAMVNAL
EALAVLGYAASDARRLAAKRALEKLLVVDASSAYCQPCVSPVWDSALASLALQETGGAAA
LAASVRALDWPQPLQLLDKPGDWRVRRPQLAGGGWAFQFANAHYPDLDDTAVVAWSMHQA
GDPARYAHNIERALDWLVGMQSRNGGFASFDIDNTHYYLNEIPFADHGALLDPPTSDVTA
RVVTVLARVGRPQDQAALGRAIAFLRKEQEADGSWFGRWGTNYIYGTWSVLTAFAQAGIG
ADDPATRRAVSWLVARQNADGGWGESNDTYAYGQQAAGKSASAPHQSAWALLGLLAAGEV
GTDAVRRGVEYLLRTQQDDGLWSDPSFTAPGFPRVFYLRYHGYCAYFPLWALAAYRTLIR
LGTTH
>A0A3M1S6F5|squalene-hopene cyclase|EC 5.4.99.17|Gammaproteobacteria bacterium|TrEMBL
MDALARIRDARDTPVNAAIAAAAAWLREQQSPEGFWAGMLESNACMEAEWLLAFHVIGYR
YPDTDGLLRGILERQRADGAWEIYYQAPTGDINATVESYAALRAYGYPPDAEPLRRAREW
ILANGGLPRTRVFTRYWLALIGEWPWQATPNLPPELIRLPRWFPFNIYNFACWARATMLP
IALLSARRHVRPLPAGRRLDELFPGGRDAMDYRLPRREGWLSWSGFFLAADRILHALQNA
GLTPGRRAAIARCIEWIVRHQDADGAWGGIQPPWVYAVMALHAEGYALDHPVMRRALSAL
EAHWTFTRGECRYLQASESPVWDTALAILAMLDCGEPADSPTLRAAAQWLLAQEVRYPGD
WTQTVKGVEPGGWAFERANLHYPDIDDTAVVLICLQRLKRIGLELPGMDAAMRRATDWML
AMQSRNGGWGAFDRDNDRRLLTRIPFCDFGETLDPPSADVTAHVIEACAALGIPREHPAV
QRGLAFLRAEQEEDGSWFGRWGVNHIYGTSAVLQALVAIGEPADSGWVAAAADWLAACQN
QDGGWGETCASYMDPDLIGHGESTPSQTAWALLGLLAAGAERHRAAIDAGLAFLAQRQQD
GSWDEPQYTGTGFPGYGVGARVALRDPVLAKRLAQGTELQRGFMINYNLYRHYFPMSALG
RARRLGFDGRATAG
>D5WE75|squalene-hopene cyclase|EC 5.4.99.17|Paraburkholderia atlantica|TrEMBL
MNDLSQTQPLDAVLPEAADAASNLAEAAVVANAPAVADALATATPSPMQTAGASPLDVSI
TRATDAILAAQQPDGHWIYELEADATIPAEYVLLVHYLGETPNLELEQKIARYLRRIQLP
NGGWPLFTDGALDISASVKAYFALKMIGDPVDAEHMVRARDAILAHGGAEHANVFTRILL
ALFGVVSWRAVPMMPVEIMLLPMWFPFHLSKVSYWARTVIVPLLVLNAKRPLARNPRKVR
IDELFRGAPVNTGMNERAPHQHAGWFGFFRCVDTVLRAVDGLLPKASRERAIRAAVAFVD
ERLNGEDGLGAIFPAMANSVMMYDVLGYPADHPNRAIARKSLDKLLVIKEDEAYCQPCLS
PVWDTSLVAHALLETREARAEQAAERGLAWLRPLQILDVRGDWISRRPNVRPGGWAFQYN
NAHYPDVDDTAVVAMAMHRSAALTKSDVDREAIARAREWVVGMQSSEGGWGAFEPENTQY
YLNNIPFSDHAALLDPPTADVSGRCLSMFAQIGELPQNSEPAQRAFDYMLQEQESDGSWY
GRWGLNYIYGTWTALCSLNAAGMSHDDPRMRRAVQWLVSIQNEDGGWGEGGESYKLDYRG
YERAPSTASQTAWALLGLMAAGEVDHDAVARGIDYLQREQREHGLWDETRFTATGFPRVF
YLRYHGYRKFFPLWALARFRHLKRNGLTRVTVGM
>A0A513RKZ1|squalene-hopene cyclase|EC 5.4.99.17|Bacillus sp. S3|TrEMBL
MMDTQAGIEWIIDMLRKDQSPGGSWGYPFETGISTDAYMIILLRTLEINDEDLIKGLTKR
ILSRQEKNGAWKLFYDEGDGNLTATVEAYYALLYSGYYQKEDTRLRSAKNFILANGGLEE
SGMYTKIMLALTGQYKWPPFSPLPIEVVLLPMNFPINFYSFSSFGRANLAPIMILADNKF
VMKTDRSPDLSPLYLQRNEIGQWTRSNEYQSLHSFIEEGVKNLLGLPEQLHQLAIERGKK
YMLDRIEPDGTFLSYFSSTFLMIFALLSLGYKKTDPVITKAVAGIQSMKCEIDGLPHMQY
TTANFWNTALIGFALQNAGVSPKDPVVVKANRYILERQHHKFGDWVVHNPNTMPGGWGFS
DVNTILPDVDDTTAALRSIARMVPNELPAWERGITWALSMQNDDGGWPAFEKDANSKLLQ
FLPIEKAEFLLADPSCADLTGRTLEFFGQYTNLPKGHTAIKRGEHWLLKNQEKDGSWYGR
WGICYLYGTWAALTGLLAAGVAKDHSSIQKAADWVRAIQNKDGGWGESCHSDRRKTYVPL
KASTLTHTAWALDSLITASDKPSPEIRKGITYLLSSLEKDDWTTDYPKGQGMAGGFYIHY
HSYRYIFPLLALSHYKKKFGS
>A0A845C9T4|squalene-hopene cyclase|EC 5.4.99.17|Holophagales bacterium|TrEMBL
MASLTRGLHERPESSPTPPPRVIDLMIDAAVRNLLGQRRDDGHWCAELEGDTILESEYVL
LLHFLGRGDDPRVAACCERLRGQQQQDGGWAIYPDGPTDPSVSVKAYLCLKLAGDDPQSP
RMADARRAILRAGGLRACNSYTRLYLSIFGLWTWRRSPAVPPELILLPRWFYFNLHEMSS
WTRTIVVPLSVIWALKPSVPLDLTLDELQGDSRPGRKRATLYESFWSFVFAGVNGLIKLV
EVIGPVPGWRRPALKKAEEWLVAHVEGSDGLGAIFPAMVNAVIAFRCLGYEESHPLVQGQ
LRELERFEIEEAGEMRLQPCLSPVWDTALSVGALLAADMDGNDAPIQEAVEWLLEREITV
AGDWREKSLQDASGGWCFEYRNDHYPDCDDTAEVLLVLAAVRDRAGELEARKQAAAARGK
RWLLGLQNPDGGWASFDRCCDKEVLTLIPFADHNAMIDPSTPDITARVISALLAHGHDPG
DGPVRRATDYLLREQEKDGSWPGRWGANGIYGTWLALSALAPLATRTGGRPEERLSRACR
LGWRWLLAAQNEDGGWGESLRSYDDPAFRGRGRSTASQTAWAMMGLIAWLEARPWNGDVA
LTVAALDRAVAFLQERQRDDGSWYDRDWTGVGFPGVFYLRYHGYAQYFPLEALAAYRRLA
VPEPDAMPANGPF
>E6PYY5|squalene-hopene cyclase|EC 5.4.99.17|mine drainage metagenome|TrEMBL
MNKVQGKTGISASPKPRFGRIDADLSLVDAAVDRSVEFLFGQQQPDGYWCGELEADAMLE
ADYIYMHVLLESGDPGHMQRALTEMLRYQNEDGSWSIYPGGPGNISLAVKCYFACKLMGM
SPDDPILARARSWILANGGVVACNTFTKMYLCALGQYDYDAVPAIPPEIVLAPNWFYFNI
YEISSWSRAILVPLSIIYAKKPYKKIPPEQGIDELFVGGRENSDLRLQFDRKRPISWRNF
FLLVDRAFHVVEAVYIRPLRKLAIRKAEQWMLDRLEMSDGLGAIYPAMMNAIIALRCLGY
SDDDPQVIRARDEFEKLGIEEEPGGNHPEPTFRMQPCMSPVWDTAYAVFALGEAGIPRTD
PRLLRAVDWMLAKEVRHKGDWAEKVRNTEPGGWYFEFNNEFYPDTDDTAQVLLALSRVEN
PRERYQYEVSQRAIRWLFAMQCGNGGWASFDKDNTKMIFQYIPFADHNAMLDPPTVDITG
RVLEMLSNYGYTRSDKRVERAVQFLFREQEPDGSWFGRWGVNYIYGTFLVLRGLEAIGVE
HNEPQIQQAAEWIRMVQNSDGGWGETCGSYDDPNTRGIGPSTPSQTAWAILGLLAAGDNR
SDSVAKGIRWLLDRQKESGDWDESVGSGVTQQALYTGTGFPRVFYLAYHMYRNYFPLLAL
TTYKRAMQTIH
>A0A3N8NWM5|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia contaminans|TrEMBL
MNDLTEMATLSAGAVPAGVDTAVARATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGKYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AIDGLFPNYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANSVMMYDALGYAEDHPNRAI
ARKSIEKLLVVHDDEAYCQPCLSPVWDTSLAAHALLETRDARAEDAAIRGLEWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAVAMERAQQLKQNDAYRDSIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLSQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNHPAVARGIDYLI
AEQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNTTRVTVGL
>A0A4Q4IFX9|squalene-hopene cyclase|EC 5.4.99.17|Sporolactobacillus sp. THM7-4|TrEMBL
MQQVEHEINRIVRVLYKDQSVDGSWKHPFETGIVTDCYMIILLRVLEWQDEPLIQSLAHR
IIKKQERNGSWKLFPDESGGNVSATAEAYSALLYSGYRTKNDPDIQAAKRFILSKGGLDK
TSTFTKTMFAITGQYPWSELFQLPVEIILLPVSFPVHFFDLAVFTRANLAPVLILSDAQY
SVKTNGTPDLSDLHQSRDSGVHFLDSAQRQSITDLIEQGIQTLAGLPEGAHSKALQEAEQ
YMIQRIEPDGTLESYFSSTLLMIFALMSRGYSKRHPIILKAVQGILSMICRIDGNAHVQY
TTATVWNTALISSALQKAGIAHSSPVIRKANHYILSRQHIKYGDWAIRNPVSQPGGWGFS
NINTINPDVDDTAYALRAIQFAARENQPFRHAWDRGVKWLISMQNDDGGWPSFERNVDKE
FITWLPIEGAEDLLIDPSTPDLTGRTLNFFGSSTVLDKQYPMIRRGIEWLINHQEKNGSW
QGRWGICYIYGTWAAVTGLIATGLEPEHPAIRKAVKWLTGIQNSDGGWGESCKSDIEKRY
VPLKISTRAQTAWALDALIAASPSITPEMEHGIEFLVNERAQPDGAESYPTGRGMAGAFY
MHYHSYTWIWPLIALSHFRTKFAGS
>A0A2T7YNC6|squalene-hopene cyclase|EC 5.4.99.17|Bacillus thuringiensis|TrEMBL
MLLYEKVHKEIARRTTALQTMQRQDGTWRFCFEGAPLTDCHMIFLLKLLGRDKEIEPFVK
RLASLQTNEGTWKLYEDEVGGNLSATIQSYAALLASEKYTKEDANMKRAEMFINERGGVA
RAHFMTKFLLAIHGEYEYPSLFHLPTPIMFLQNDSPLSIFELSSSARIHLIPMMLCLNKR
FRVGKKLLPNLNHIAGGGGEWFREDRSPVFQTLVSDVKKIITYPLSLHHKGYEEVERFMK
ERIDENGTLYSYATASFYMIYALLALGHSIQSPIIEKAIMGITSYIWKMERGSHLQNSPS
TIWDTALLSYALQEAQVPKASKVIHNASAYLLRKQQTKKVDWSVHAPDLFPGGWGFSDVN
TTIPDIDDTTAVLRALARSRGNENVDNAWKRAVNWVKGLQNNDGGWGAFEKGVTSRILAN
LPIENASDMITDPSTPDITGRVLEFFGTYAQNELPEKQKQSAINWLMNAQEENGSWYGKW
GICYIYGTWAVLTGLRSLGIPSSDPSLKRAALWLEHIQHEDGGWGESCHSSVEKRFVTLP
FSTPSQTAWALDALISYYDKETSVIRKGISYLLSNPYINEKYPTGTGLPGGFYIRYHSYA
HIYPLLTLAHYAKKYRK
>A0A7C7MLI1|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
MTVYQENRVDAPSGEHLELAITRCREFFRQNQYDDGYWWGELESNPTMEAEYLLLSHFLG
KPEKDRWRKVCNQILQKQCDDGSWGQYYQAPGDLSTSVECYFALKLAGHSSDEVYMSKAR
AFILSRGGIPNSRIFTKIWLALFGQWDWKGVPNLPPELILVPPSLPFSVYDFAGWARPTI
VPMLVILSRRPYCPIPDWAHLDELYPKPREETDYSLPKPQSRWGWAKLLYHLDQLAGLYQ
LFPVHPLRGWAERKIVDWVVGHQEPNGSWAGIQPPWVYSLIALHHMGFPSDHPVMEKGFA
GIDGYAIEDEDTFSVQGCISPVWDTCLAQVGLIESGVGEADPMIQKSTRWLLDRQILEPG
DWQVRAKNVEPGGWAFEFDNNRYPDIDDTSEVIMALNLARLGPEDDPRRRHAIKRGVNWI
LALQSKDGGWGAFDKDNNRSYVSRLPFSDFGEVLDPTSVDVTAHILEMMGKLGYRQDFPP
LSRALRYILDRQEEDGSWFGRWGVNHIYGVGAVLPALAAIKEDMSQPYVLRAVEWLVAHQ
NGDGGWGESCGSYVDPDLRGVGPSTPSQTSWALIALLAAGKETSDPVIRGVRYLLETQDE
GGCWDEPYFTGTGFPGYGAGEPPKTLPKPGELGYQGLDMPGGFMINYHMYRNYWPLMALG
RYKRQTSDHHWDAIQTNGTEPQKTYVQGEASQYES
>A0A4R5EQ14|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. 6K520|TrEMBL
MTAVETGTRTRTAAEALAAAREHLLLLQSPEGWWKGELQTNVTMDAEDLLLREFLGIRTG
ADTDETARWIRSQQAPDGTWATFHDGPPDLSTTVEAYVALRLAGDPPDAGHMVRAAAHIR
GAGGIPATRVFTRFWLAMFGRWPWDELPVLPPEMMYLPRWFPLNVYDWACWARQTIVPLA
VVGALRPVRPLPFGLAELTPEDGVPRSRTRGLPGWDTAFETLDRALHVYERRPVQGLRRA
ALRRAGEWIIARQERDGSWGGIQPPMVYSLIALHLLGYGLDHPVVRRGLDGLERFTIRDG
KGRRVEACQSPVWDTVLAMNALADAGLPEGHPALERAAEWVLGEEVRGPGDWSVRRPGLP
PGGWAFEFDNDCYPDVDDTAEAVIALHRVRHPPAEPAIERGVRWMAGMASRDGGFGAFDA
DNTRGLCRRLPFCDFGEVIDPPSADVTAHVVEAMAHRGMADSLTVKRAVVWLLKAQEPDG
SWFGRWGANHVYGTGAVVPALIAAGVRPGRPEIRGAVHWLERHQRDDGGWGEDLRSYRDP
AWIGRGVSTPSQTAWALLALLAAGERGAAVERGVGWLVEHQRADGTWDEDHFTGTGFPGD
FYINYHLYRLVFPLSALGRYLKGA
>A0A6L8HXN3|squalene-hopene cyclase|EC 5.4.99.17|Dehalococcoidia bacterium|TrEMBL
LVVWAYRPVVPIPDYAHVDELYLDPADRRSIPLRRDRQPFTWRNAFLAIDRVLHAHERLP
WKPLRDFSLKECERWIIEHQEADGTWGVIQPPSVYSLIALRAHGYSMDHPVMQKGLNGFL
GDFALRRGNTFSVQPCLSPVWDTALAVTGLREAGVPADDEALVQAGRWLLAHEVQSLGDW
ALTVPGIEPGGFPFEFSNELYPDTDDTAEVLIALRLLDLRGKDGPFHRSKVWLRAMQSTN
GGWGAFDRDNDDEFVSRIPFADFGATFDPPTEDVTAHILEAFALDGTPPSDEMMDRALDY
LWDTQEPDGSWWGRWGVNYLYGLGAAVPALVAAGVDPADPRLRRAVRWLEHHQQPDGGWG
ESCATYEDPSLRGQGPSTASQTAWALLALLAVEPPDHPATVRGIDYLVRTQTDDGEWIEP
HFTGTGFPRDFMLKYHLYSNYWPLWALGRYRRLRDGNPIHLPETDPLG
>A0A4R4FMP3|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia pyrrocinia|TrEMBL
MIRRMNKPAPSPWSALDTAIARGRDALVRLQQPDGSWCFELESDATITAEYILMMHFMDR
IDDVRQQKMARYLRANQRLDTHGGWDLYVDGAPDVSCSVKAYFALKAAGDSEHAPHMVRA
RDAILKLGGAARSNVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARARNPRNVSIRELFVTPPDQERHYFPPARGMRKLFLALDRTVRHLEPL
MPKRLRRRAIRHAEAWCAERMNGEDGLGGIFPPIVYSYQMMEVLGYPDDHPLRRDCENAL
EKLLVTRPDGSVYCQPCLSPVWDTAWSTMALEQARGVAVPEGGEPAGALRELDERIARAY
DWLAGCQVNDLHGDWIENAPADTEPGGWAFQYANPYYPDIDDSALVTAMLDRRGRTHRNA
DGTNPYAPRVVRALDWMRGLQSRNGGFAAFDADCDRMYLNAIPFADHGALLDPPTEDVSG
RVLLCFGVTKRADDRAALARCIDYVKRTQQPDGSWWGRWGTNYLYGTWSVLAGLALAGED
KSQPYIARALDWLRARQHADGGWGETNDSYIDPKLAGTNSGESTSNCTAWALLAQMAFGD
CESDSVKRGIAYLLSVQQDDGFWWHRSHNAPGFPRIFYLKYHGYTAYFPLWALARYRRLA
GAASSPGSTVRGTMAVETTDTAVA
>A0A8J7C5J2|squalene-hopene cyclase|EC 5.4.99.17|Iningainema tapete BLCC-T55|TrEMBL
MQIQDRATASIATAIAASQNYLLSLQNPSGYWWAELESNVTITAEVVLLHKIWVTDKSRP
LHKVETYLRSQQREHGGWELFYGDGGELSTSVEAYMALKLLGVPATDPAMLKARNFIIAR
GGISKTRIFTKFHLALIGCYNWRGLPSLPPWVMLLPSTFFFNIYELSSWARSSTVPLLIV
FDRKPVYQVNPGITLNELYAEGADKVAFELPRNNDWTDLFILLDNAFKLAEDLNLMPLRE
EGIKAAERWVIERQEATGDWGGIIPAMLNSLLALRCLGYDAADPIVERGLQAVDNFVIET
EDTYTVQPCVSPVWDTAWVVRALVDSGFAPDHPAVVRAGEWLLSKQILDYGDWAVKNRQG
KPGAWAFEFDNRFYPDVDDTAVVVMALDGVKLKNDKLKQAAIARAVNWVASMQCQAGGWA
AFDKDNNQDWLNLIPYGDLKAMIDPNTADVTARVLEMLGSCNLAIDAQNLERSLAYLIRE
QETEGCWFGRWGVNYIYGTSGVLSALSSIAPQKCRNHIERGAAWLVGCQNPDGGWGETCR
SYNDPGLKGKGVSTASQTAWAILGLIDAGKATGKMAELSIRRGIDYLVETQLEDGSWYES
EFTGTGFPGHFYLKYHMYQQYFPLMALGRYRVMVDL
>A0A6P0TE43|squalene-hopene cyclase|EC 5.4.99.17|Cyanothece sp. SIO2G6|TrEMBL
MDEHERLQEAIATSQRYLLAQQNPEGYWWAELESNVTITAEVVLLHKIWGTDLNRPLHKV
EAYLRREQRDHGGWELFYGDGGNLSTSVEAYMALRLLGVPITDPALVNAKQFILAQGGIS
KCRVFTKFHLALIGCHDWRGVPSIPPWIMLLPQSYPIYEMSSWARGSTVPLLIVFDQKPV
YLTDPTVNLDELYLEGRDNADYSFPQNGDWTDIFLGLDQVFKLAEEWNLVPLRAEGLQAA
EKWVLERQEATGDWGGIIPAMLNSMLALRSLGYDANDPIAIKGFDAIDQFAIESDTTYHI
QPCISPVWDTAWCIRALRDSGMGASHPSLVQATQWLLDKQILDYGDWAVKNIQGRPGGWA
FEFVNNWYPDVDDSAVVVMALSQVQFPNEPRANGKLPAIEAVKQGAIARTVDWIATMQCD
PGGWGAFDINNDQDWLNALPYADLKAMIDPNTADVTARVLEMVGYLSAEPAYERSHCQPL
PSELYQHNPYRTIPNLLPTKTLPLPGKLWRSLQYLLDEQESDGAWFGRWGVNYIYGTSGA
LSALALVKPDNHQRAIAQGAAWLVQCQNADGGWGETCWSYNDPSLRGQGDSTASQTAWAL
IGLIAAVDAITDAAIAEASMPAIHQGIQYLIQTQQTDGSWDEAYFTGTGFPCHFYLKYHM
YQQYFPLIALGRYHARFSNP
>A0A432RKP0|squalene-hopene cyclase|EC 5.4.99.17|Methylococcus sp|TrEMBL
MLKDTAQANLRKEPAEKGTALPEGNWKTSLEPAIKKAESSLRKAQKTDGHWVFELEADCT
IPSEYITMMHYLGEVDELLQAKITNYLRARQNKDGSYSLFTGGPGDISCTTKVYFALKLA
GDSSQRPHMRKAREYVLSQGGAAKCNVSTRILLAIFEQVPWKAVPYIPVEIMLLPKWFPF
HLDKVSYWSRAVMVPLFVLCTLKAKAVNPSSTNIRELFVTAPEIEEHYFPKRGLLNKVFL
GLDFLGRSLEPFIPKRMRKKALRAAQQWIRTRLNGEDGLGGIFPAMVLAYEALLLLGMPK
DHPDVVIGKKAMKKLLVVNDHDAYFQPCLSPIWDTGLAILALQEADSKENSEEIDRGLDW
ITERQLDDEPGDWRIACPEYQGGGGWAFEYENPYYPDVDDTALVAYALTQTSETRFHESA
RKAARWVHVMQSRNGGFGAFDIDNTHYYLNEIPFADHGALLDPPTADVSARCAMFMARMV
DEHPEYRNTLDQAITYLRNEQETDGSWFGRWGTNYIYGTWSVLVALEQIGISSDDPMFKD
AVCWLKSKQNSDGGWGEDNLSYHDTDYSGKYSFSTSFQTAWALLGLMAARETDSAEVRAG
INYLLKTQESDGFWNDPCFTAPGFPRVFYLKYHGYSKYFPLWALARFRNTECRK
>A0A496QL47|squalene-hopene cyclase|EC 5.4.99.17|Thermodesulfobacteria bacterium|TrEMBL
MGSTPHSMITDSLQQGIKNGVSWLLDNHRPEGFWVGNLETNSCMEAEWVLAMHFLGIEND
PKYESVIRAILNEQRPDGSWEVYYQAPIGDINTTVECYTALRASGMPVDAMPLHKARKWI
FEHGGLGDLRVFTRYWLALFGEWPWDAIPALPPEIIFLPSWAPFNFYQFASWARGTIIPL
TVLSARRPVRKFPPEHRIDELFPKTRNRFDYRSAGKGHTSFRQRPFYWSDRLLSRYTGFP
FHPGRESAIRQCLEWIIRHQEADGAWSGIQPPWIYSLMALHVEGYAIDHPVLAAGLDAWN
QHWKFEKNGATYLQASDTPVWDTLLSLLALLDCRQDFNAIPQMQAALEWILNEQVMAGGD
WQVYVKDVESGGWAFERQNDFYPDVDDTAVAIIVLLRLLPALHGSGLRSRIDTAVRKAVA
WMNAMQSSNGGWGAFDKDNNSRFITLIPFCDFGETLDPPSVDVTAHVLEALGLLGRGTDD
PVVARAYRYVRSEQEEDGSWFGRWGVNHIYGTSAVLPALEAIGEDMNAPYVQKAAQWIVD
HQNPDGGWGESCGSYMDITLRGCGPSTASQTGWALMALVATGSHAYDPVIEKGLAWLLAT
QRADGTWDEPQYTGTGFPGYGIGERTDIAKAVDKLDQGSELARGFMLNYNMYRHYFPLMA
MGRARHHLLKRK
>B1FEM3|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia ambifaria IOP40-10|TrEMBL
MNDLTEMATLSAGTAPAGLDAAVASATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGRYLRRVQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPIAKNPRGVRIDELFVDPPVNAGLLPRQGHQSPGWFAFFRVVDHALR
AADGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKSIEKLLVVQEDEAYCQPCLSPVWDTSLAAHALLETGEARAEEAVIRGLEWLRPLQIL
DVRGDWISRRPHVRPGGWAFQYANPHYPDVDDTAVVAVAMDRVQKLKHNDAFRDSIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQLGETPL
NSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCALNAAGLTPDDPRVKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGVEYLI
AEQKEHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRDNATRVTFGL
>A0A5D0NUX5|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura chibensis|TrEMBL
MTTTDVSGLTGAAAAAAEAARDHLLRLQSPEGWWKGELETNVTMDAEDLLLRQFLGIRSA
ADTEEAARWIRSQQREDGTWANFHGGPPDLSTSIEAYVALRLARDPVDADHMRRAAAYVR
ESGGIEASRVFTRIWLALFGQWSWDDLPVMPPELMFLPSRVPLNVYDWGCWARQTIVPLT
VLGSLRPVRALPFDLPELRSGVRPVKEERGWGRFFTGLDRVLHVYQRRPVGPLRRAAIRR
AADWIIARQEADGCWGGIQPPWVYSLMALHELGYGLDHPVIKRGLAGLDRFTIRDEKGRR
LEACQSPVWDTVLAINALGDAGVPADDPALRRAAAWVVAEEVRGLGDWAVRRPDVPPGGW
AFEFDNDIYPDTDDTAEAILALRKVELPEAEEPIRRAVRWLEGMASRDGGYGAFDADNTR
ELCTKLPFCDFGAVIDPPSADVTAHVVEALAGEGLAESRTVKRAVVWLLRAQEADGSWFG
RWGANHVYGTGSVVPALVAAGVPAHKPPIRRAVAWLEAHQNPDGGWGEDLRSYDDPAWIG
RGESTASQTAWALLALLAAGERSGAVDAGVRWLVDHQRPDGTWDEDQFTGTGFPGDFYIN
YHLYRLVFPISALGRYLGGAA
>A0A7X1HZF3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces mexicanus|TrEMBL
MTATTDGSTGATLPPRAASASDSVPSTPEAAGVKQAAALAVRRATDYLLSKQDTEGWWKG
DLETNVTMDAEDLLLRQFLGIRDEKTTQAAALFIRGEQREDGTWATFYGGPGELSTTIEA
YVALRLAGDAPDAPHMAKASAWIREQGGIAASRVFTRIWLALFGWWKWEDLPELPPELIY
FPTWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAVPNPPRPLAPVAS
WDGAFQRIDKALHAFRKVAPKRLRRAAINSAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPADHPQ
LVKAADWMLGEQIVRPGDWSVRRPTLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHD
PERVDKAVRRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAYEGLSHDPRTRRGIEWLLAEQEPNGSWFGRWGVNYIYGTGSVVPALTAAGLPGSH
PAIRRAVAWLESVQNDDGGWGEDLRSYKYSKEWAGKGASTPSQTAWALMALLAAGEQDSK
AVERGIEWLAAAQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPVVG
TARAAAAADRSPAEVKGNG
>A0A525IAH9|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp|TrEMBL
MHSGNSPGGSEIDGALGASIGSATRALLGYRQPDGHWVFELEADCTIPAEYVLLRHYLGE
PVDRVLEAKIANYLRRVQGAHGGWPLVHDGDFEMSASVKAYFALKMIGDSADAPHMVRAR
EAIRSRGGAIHSNVFTRFMLAMFGVTTWRCVPVLPVEIMLLPMWSPFHLNKISYWARTTI
VPLMVLAALKPRAKNVSGVGIDELFLQDPRSIGMTAKAPHQSWGWFLLFRGLDSVLRTIE
PLFPKKLRARAIDAAIAFIEERLNGEDGLGAIYPPMANAVMMYEVLGKPADYPPRAVTRK
GLDKLLVIGEHEAYCQPCVSPVWDTSLTCHALIEAGGEEALPPAKQGLDWLVPKQVLDVK
GDWAVKRPEVRPGGWAFQYNNAYYPDLDDTAVVVMAMDRARRSAPNPAYDAAIARGREWI
EGMQSRDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISMLAQLGETAQSSK
AVADGIDYLRRTQLAEGSWYGRWGLNYIYGTWSALCALNAAGMDHQDPAIRKAVDWLVSI
QNKDGGWGEEATSYRLDYRGFEGAPTTASQTAWALLGLMAAGEVGHPAVARGVEYLIATQ
TEKGLWDEPNYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRITNSRVVGVGM
>A0A5M6IKI6|squalene-hopene cyclase|EC 5.4.99.17|Rhodovastum atsumiense|TrEMBL
MEKSPLPHDLLATVPHDQLSDAVNRARAALLRRQQPDGHWVFELEADATIPAEYVLLEHF
LDRIDAPLQDRIATYLRSIQGEHGGWPLFHDGDFNLSASVKAYFALKIIGDDPDAPHMVR
ARAAILGAGGAERANVFTRAQLALFGEVPWHAVPVMPVEMVLLPKWFPFHLDKVSYWSRT
VIVPLVVLMALRPRARNPRGVHVPELFRTPPEQVRDWIRGPYRSAWGRFFKHLDSVLRVA
EPHFPKTVRKRAIDWAVAFVTERLNGEDGLGGIYPAMANTVMMFDSLGYPSDHPDAAIAW
ASVRKLLVVEEDRAYCQPCLSPVWDTALSGHAVAEADSAADPTIDNACSWLRGKQVLDLV
GDWAASRPDAVPGGWAFQYENAHYPDVDDTAVVGMLLHRNGQAGGDPGNDEAIARARDWV
IGMQGKDGGWGAFDADNNHHYLNHIPFADHGALLDPSTADVTARCVSFLAQTGMPADHPV
MARALAWLRSEQEADGAWFGRWGTNYIYGTWSVLCALNAAGVPAEDPAVRRAVGFLLETQ
REDGGWGEDNETYADAPRGRYHRSNPSQTAWALLGLMAAGEAEHPAVARGIAWLAAQQKP
DGEWDEAPYTAVGFPRVFYLRYHGYKLFFPLLAMARYRNLMRGNDRRVAWGF
>A0A8J6Y3L2|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Sulfomarinibacter kjeldsenii|TrEMBL
MAVAVRCEQPKRVESGRLNDAIAKARSALLADQHPDGHWCYELEADCTIPSEYVLFLRYL
GESEPELEAKIGRYLRSRQAENGGWPLYLGGDLDISCTVKAYYALKLVGDDPEAPHMVRA
REALLSRGGAARANVFTRIALAIFGQLPWRAVPFIPPEIMLLPKWFPFHIDKVSYWSRTV
MVPLFVIYAFKARAANPSGIGVRELFKKDPEIERDYFPVRSILNRLILWLERAVRPLEPL
IPRGIRRKALQKAEAWFTPRCNKGGLGAIFPAMINAYMALRLLGHNEAEPVMVQAREAID
DLLVVDGGSAYCQPCVSPVWDTGLASLALLEDGAEKNRGELSRALEWLAPLQLLDDPGDW
RINHPDLAGGGWAFQYENAYYPDLDDTAVVAWAMHLAADRERFEEPIRRAADWLCGMQSK
NGGFAAFESDNTHYSLNEIPFADHGALLDPPTSDVSARCVALMGQLARTEDAECVRRTLR
YLRDEQESNGSWFGRWGSNYIYGTWSVLSALEHVPEADTFAMVKPAVSWLRLIQHADGGW
GETNDSYLDPARSCEGDRSTAFQTAWALLGLMAAGEGDSEAVRRGVEYLLEVQEAEGGWS
DPEFTAPGFPRVFYLRYHGYSMFFPLWALARYRNHLVDR
>A0A4S2TEJ7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. A1136|TrEMBL
MTATTDGGGAPGAGPAREPAATPGAVPGVRDATERATRHLLDRQDPAGWWKGDLETNVTM
DAEDLLLRQFLGIRDEATTRAAARFIRGEQREDGTWATFHGGPPELSATVEAYVALRLAG
DPPDAPHMARASAWVRAHGGIAAARVFTRIWLALFGWWKWDRLPELPPELVFLPPWVPLN
IYDFGCWARQTIVPLTVVSALRPVRPAPFALDELHADARNPDPVKPAAPLLSWDGAFQRM
DRALHVYRRFAPRRLRGAAMNTAARWIIERQENDGCWGGIQPPAVYSVIALHLLGYDLGH
PVMRAGLESLDRFAVWREDGSRMIEACQSPVWDTCLAAIALADAGVPADHPALLKAADWM
LGEEITRSGDWAVRRPGLAPGGWAFEFHNDTYPDIDDTAEVVLALRRIAHPEPAKVEAAI
ARGVAWNLGMQSKNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTAHVVEMLAVEG
KAGDPRTRRGIDWLLAEQEPGGAWFGRWGTNYVYGTGSVVPALTAAGLSTDHPAIRRAVA
WLESVQNEDGGWGEDQRSYKDPDWAGKGASTASQTAWALMALLSAGEREGKAVERGVAHL
VRTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLYGEPFGPDGRYTARPA
GEATARPAGQTTSEPAPATAAGPVPRPMADPVREATAILAEEA
>A0A4S3GBT5|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. A1499|TrEMBL
MTATTDGSTGAVTPRAASASHSIDTPAATPPTAGTREAAALAIQRSTDFLLSRQDAEGWW
KGDLETNVTMDAEDLLLRQFLGIGDERTTRAAALFIRGEQREDGTWATFFGGPGELSTTI
EAYVALRLAGDLPDAPHMARAAEWIRDRGGIAESRVFTRIWLALFGWWSWDDLPELPPEL
IYFPPWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHVDARVPRPPKPLAPA
TSWDGLFERLDKALHVYHKVAPRRLRGAAMNSAARWIIERQENDGCWGGIQPPAVYSIIA
LHLLGYDLEHPVLKAGLASLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADH
PQLVRAADWMLGEEIVRPGDWAVRKPRLAPGGWAFEFHNDNYPDIDDTAEVALALRRVAH
PDQARVDNAIARGMRWTLGMQSKNGAWAAFDADNTSPFPNRLPFCDFGEVIDPPSADVTG
HVVEMLAVEGRSHDPRTRRGIEWLLAEQEDNGAWFGRWGVNYLYGTGSVVPALITAGLPA
SHAAIRRAVRWVESVQNDDGGWGEDLRSYRDRGWVGHGTSTASQTAWALLTLLSAGEREA
PSVERGIAWLAATQRPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPFP
AGSAHAGKGS
>A0A7Y4WBV3|squalene-hopene cyclase|EC 5.4.99.17|Nitrospiraceae bacterium|TrEMBL
MKLIRTLLDRLSDSLFVSVPEMRGLAAEPSNIPPLRLVSDKPLLSAPVDTAARRPANPIS
QMDALDDAVRRSQAWFLSRQDTAEGYWVAELEADTTLTAEYLMLRRFLDRVDPERERRAV
HYLRAMQLPDGGWPIFYGGPSEISASVKAYFALKLSGVSVDEPFMVRAKDCILAKGGVVQ
ANVFTKIALALFDQYDWEGIPHMPVELMLLPKGFYFNIYAISYWSRAVLVPLLIIFAHRP
VCRIPREQGIEELYLVPRKEIRYWKFPPFNKDQKWFTPHNLFVALDAMLKLYDRMPLLWL
REKAVHRTATWMLEHIKGSGGLGAIYPAMSNSIIALQCLGYQVDDPLVRKAFHEIEALEV
YDKASIGDQRVDTLHLQPCHSPIWDTALLLNALIETGMPQDHPSLQKAAAYLVSRQTQTV
GDWKFSSPDAEPGGWYFQFENELYPDVDDSAVVLMGLSKIQMPQTTDLQQSIQRGMKWVL
AMQGSDGGWGAYDKDNNRIVFNYIPFADHHALLDPSTSDLTGRCLEMLAALGYDQTHPAV
APALRFLKREQEADGSWFGRWGVNYIYGTWSVLAGLHAIGEDLSKPYVRRAVTWLESKQN
PDGGWGESCLSYGDPAWSGKGDSTPSQTAWAIMGLMSAGMTDAFSVARGVQYLLRHQTKD
GSWEEVRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRTRGKMRADEVRQQVLASGCH
RAGH
>A0A838C2N0|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia gladioli|TrEMBL
MIRPMKNSDLPLPSMLDAAILRGRDALAQRQNADGSWCFELESDATITAEYILMMHFMGK
IDDARQARMARYLREIQRLATHGGWDLYVDGAPDVSASVKAYFALKAAGDSEHAPHMARA
RDTILRLGGAAKCNVFTRILLATFGQVPWRATPFMPIEFVLFPKWVPISMYKVAYWARTT
MVPLLVLCSLKARAKNPRGISIRELFVTAPEDERNYFARGGFVRNLFLGIDRTLRPLDAL
IPKALRRRAIRHAEAWCAERMNGEDGMGGIFPPIVYSYQMMEVLGYAEDHPLRRDCEDAL
EKLLVERPDGSMYCQPCLSPVWDTAWATMALEQARAVPDTRDRPPVSEADLQAGITRAYD
WMAGKQVTELKGDWIENAPAETPAGGWAFQYENPYYPDIDDSAVVAAMLHQRGRAMARLT
GTDPYAEVVTRGLDWIRGLQSRNGGFGAFDADCDRLYLNLIPFADHGALLDPPTEDVSGR
VLLCFGVTGRAEDRPALARAIEYVKRTQREDGSWWGRWGTNYIYGTWSVLAGLALAGEDR
SQPYIARAIDWLRARQNADGGWGETNDSYVDPALAGTNGGESASNFTAWALLAQMAFGDW
QSESVQRGIRYLLSVQQGDGFWWHRSHNAPGFPRIYYLKYHGYTAYFPLWALARYRRLSQ
ARVAASDAPAAAAALH
>A0A7M2A748|squalene-hopene cyclase|EC 5.4.99.17|Paenibacillus sp. JNUCC-31|TrEMBL
MGHVLGAIDEEMSRMTTSLLHQQQRDGSWHFCFENGTVIDAYVIILFRILDVPNEVLIRQ
LHDRILNEQQPNGCWKLYPDEEEGNLSASVEAYYALLYSGYSQRTDEPIQRAKRYIQSKG
GIGKVTSILTRAILAATGQMKWPLSISMIPLEILMFPTYFPINYFEFSGYSRVHLTPMLI
MADLRFSLTIPNAPDLSDLTDLRMVADESTSREYQEMQEGIQTGRSRLLGNPRHIHDTAR
TKAEQFMIERIESDGTLYSYASSTILMVFALLALKYDKQHPLITKAVTGLAAMQCRSSEG
KTTIQNSPSTVWDTALITYALQEASITDDHKAIQRAASYLISHQQDKTADWSIHNSNTVP
GGWGFSESNTLNPDVDDTTAALRAIRSLSTTIPTFQKSWNRGLNWVLSMQNKDGGWPAFE
KNTNKEVLTWLAIDGAKSAATDPSEPDLTGRTLEYLGNFAGLDSKHEFIQRAVKWIVRNQ
EKDGSWYGRWGVCYIYGTWAALTGLRAVGLPESHDTVQKGSQWLLSIQNSDGGWGESCHS
DRLLRYVPLGESTPSQTAWALDALIAVQPKPTPEMNQGILRLIASIGENDWRTSYPTGAG
LPGNFYSHYHSYTYIWPLLTLSHYRKKYGTS
>A0A7T0G0I5|squalene-hopene cyclase|EC 5.4.99.17|Candidatus Nitronauta litoralis|TrEMBL
MESTEEPTTPDTELNQDLDSPLENLQQNSTALDNTIAAARDYHFSTQYKEGYWVEELESN
ATITAEFVFLMHFLGIEDRYRDRREKIRNFLLQNQREHGGWDLFYGGPPDISATIEAYIA
LKMLDVSPHDPAMAKARKVIEDLGGVRSARVFTKIFLAMLGQSSWDDTPVMPVELILLPN
WFYFNVYEMSSWSRGTVVPLTMVYAHKPVWPLSEEHSVPELFTPADRDLSVKSTKPGLNW
PNTFLFIDKTLKTLGKLGWKPLRKAAMKKALRWTLDHQEPEGDFSGIQPAMFNSILALHL
QGYSLDNPIMVRAFEAVDRFLIDREDHTLLQACVSPLWDTAIAANALMDSGVQEDHPSIV
QACDWMLTKQVTRRGDWRFKNPGTPAGGWAFEFFNESYPDCDDTAEILMALDRAKLQDEK
YKQREMDRALNWLFSMQSTNGGWAAFDRDNDHELFNEIPFADHGAMLDPPTVDVTGRILW
MLGRIGHPTDEPRVRQAIDFIYSEQEHDGCWWGRWGVNYIYGTWLVLMGLRSIGEDMTQP
RIKKASDWIKSKQNEDGGWGETCDSYIDPKLRGQGHSTCSQTAWALMGLIETGEAGSNAA
TKGVQYLIDQQQEDGSWYEDYFTGTGFPGHFYIRYHMYRQFFPLMALSRYRTALQSQT
>A0A7T4FZH3|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus necator|TrEMBL
MSMNETAFATAVPRIAPASAGDSPAPRDAAQALDQGIGRAIDALLHQQRPDGHWVYELEA
DATIPAEYVLMVHYLGEAPDLELEARLARYLRRIQNPDGGWPLFHEGRSDVSASVKAYFA
LKMAGDDPQAAHMQRARRAVHALGGAEASNVFTRTLLALYGVMPWLAVPMMPVEIMLLPQ
WFPFHLSKVSYWARTVIVPLLVLNSLRPQARNPRGVGINELFVGNCHTVGLPPRAAHQHA
GWYTVFRGLDALLRVAEPLVPRTLRRRAIAAAQAFVRERLNGEDGLGAIFPAMANSVMMF
DVLGVPPDDPARALARQSVERLLVEHGDEAYCQPCLSPVWDTALAAHALLETGEARATAA
AGRGLDWLRPLQVLDVRGDWAVRRPLVRPGGWAFQYANAYYPDVDDTAVVAAAMNRYMRA
HDVPGRYDEAVARAAEWIVGMQGGDGGWGAFEPENTHLYLNNIPFADHGALLDPPTADVS
ARCLSMLCQIGATPGKSEPAARALRYLLAEQMPDGSWFGRWGTNYIYGTWSALCALNATG
LAPEAPEMRRAVAWLEQIQNADGGWGEDGSSYRLDYRGYEPAPSVASQTAWALLALMAAG
AAQHAAVARGIDYLLRTQQSGGLWHEPRFTAVGFPRVFYLRYHGYARYFPLWALARYRNL
QRGGAHQVPWGL
>A0A6M0HPA5|squalene-hopene cyclase|EC 5.4.99.17|Methylobacterium sp. BTF04|TrEMBL
MREAFKKVEALQRPKTQEISIEDVERGITRATQALTALSHADGHLCFELEADATIPSEYI
MFHQFRATEIPEGLEPKIGNYLRRTQGKHGGWSLVHDGPFDMSASVKAYYALKFAGDAVE
APHMRRAREAILSRGGAANSNVFTRFLLALFGQVPWRAVPVMPVEIMHLPRWFPFHLDKV
SYWARCVIVPLLVLQAKKPLAKNPRGLGVPELFVTPPEHVRHWPGSPHATWPWTPIFGAL
DRMLQVTQQHFPKKRRQRAIDKAEAWVSERLNGEDGLGAIFPAMVNTVLMYDVLGYPSDH
PQVRIACEAIEKLVVVKEHEAYVQPCLSPVWDTALAGHALLEAGGPEAEHQARRGLDWLK
PLQVLDIKGDWAAGRPDVRPGGWAFQYANPHFPDLDDTAVVVMAMDRATRQHGLVADVPD
YANAIARAREWVEGLQSSDGGWAAFDADNNHHYLNHIPFSDHGALLDPPTADVTARVVSM
LAQLGETRDSSKALDRGVVYLLADQEEDGSWYGRWGMNFIYGTWSVLCALNAAGVDPASP
EIRKAVAWLIRIQNPDGGWGEDASSYKIDPAFEPGYSTASQTAWALLALMAAGEADDPTV
TRGINYLTRTQGADGFWSEERYTATGFPRVFYLRYHGYPKFFPLWAMARFRNLKHSNTRA
VAYGM
>H0U5A4|squalene-hopene cyclase|EC 5.4.99.17|Brevibacillus laterosporus GI-9|TrEMBL
MKEKAELEIKRIIHLLQKAQSVDGAWRYCSESGPLTDAYMIILLRTLMIDDEELIRSLAD
RITIRQEKNGAWKLFHDEEEGNLSATIEAYYALLFSGYSQKTDEHMQLAKKFILTKGGIS
EASMLTKLLLALTGQYPWSGYFQIPVEIILLPHWLPINFFDFVGYARVHIAPILVVADRK
FVMKTRRTPDMSDLRKNDLPTALGNHPYLTNQRSHQYRAFLNTILDGFKNLPYLPSQIHN
MALRQAERYILERIEPDGTLYSYFTSTFLMIFALLSLGYSANHPVITRAISGLKAMTCLT
NGHLHIQIATSTVWNTALLAHAMQGTGVSASEPTVQNTGRYLLSRQHHKYGDWMIKNPFV
LPGGWGFSDINTINPDVDDTTAALRAISKLRETDPTFHHSWDRGLNWLLSMQNADGGWPA
FEKNTDKRIVNWLPFDAADAVSTDPSTADLTGRTLEFLGNNAGFTIGHPQIQKGVKWLLS
NQEANGSWYGRWGISYIYGTWAAITGLMAVGVSSEHPAIQKAVQWLLKIQNEDGGWGESC
KSDIVKTYVSLGASTPSQTAWGVDALISVFQKPIPVIERGIQFLIDSEKNQDWTLSYPTG
GGLPGGFYFHYHSYQYIWPLLALGNYKKKY
>A0A856LNU2|squalene-hopene cyclase|EC 5.4.99.17|Pandoraea pnomenusa|TrEMBL
MATQTLESGIERSIAALLDLQQDDGHWLFELEADSTIPAEYVLLRHHLGEKVDAELEGKI
AAYLRRIQGEHGGWPLFQDGKFDMSASVKAYFALKMIGEPIDAPHMVRAREAILSRGGAQ
NSNVFTRILLALYGVLDWKAVPMMPVEIMLLPKWFPFHLSKVSYWARTVIVPLLVLQARR
PLARNPKGVQIDELFIGNPKDVGPPKRAPHQSRFWFTFFSGVDHVLRALDPCFPKRLRQK
SIDRAVAFVEERLNGEDGLGAIYPAMANAVMMYDVLGYPEDHPSRAIARKSVEKLVTPAD
HETYVQPCLSPVWDTALSAHALLETGDKRAIEMAGKGLEWLIPLQILDVRGDWISRRPNV
RPGGWAFQFANPHYPDVDDTAVVAMAMDRYEKLAGKFENDKVDASTRPMRHAIDRGTEWV
IGMQSSNGGWGAFEPENTHLYLNNIPFSDHGALLDPPTVDVSARCLSMLAQLPPSPERRA
SAELALKYILDDQEADGSWYGRWGMNYVYGTWSAMCGLRAAGLPPEHPALARAAQWLISI
QNADGGWGEDGDSYKLEYKGYESAPSTSSQTAWALLGLMAAGKANDPAVKRGIDYLLDTQ
NDEGLWDEALYTATGFPRVFYLRYHGYRKFFPLWALARYRNLTVRNDCPVPCGM
>A0A1Z5H7L1|squalene-hopene cyclase|EC 5.4.99.17|Bathymodiolus platifrons methanotrophic gill symbiont|TrEMBL
MFTEDYNNMSNIHSLDSAIKNAQDRLLSLQHKDGYWVFELEADCTIPAEYIMMMHYLDDI
DKGLQAKIAVYLRAHQSADGSYPLFSGGEGDISCSIKVYYALKMAGDQPEQPHMACLREY
ILSQGGAAKANVFTRIALAIFEQLPWRGVPFIPVEIMLLPAWFPFHIDKVSYWSRTVMIP
LFILCSLQAKAKNPLNIDILELFIVHPGKEMHYFPERGVLNKFFLFLDALGRKSRILVTR
KMHQTAVARAQNWFTERLNGEDGLGGIFPAMVNAYQAMLLLGMPADNEHVVTARKAIDKL
LVIREDEAYCQPCLSPVWDTGLALLALQETDLAATEGSRKRAYDWLKTKQLSDEPGDWRI
QRPNLEGGGWAFQFENPHYPDVDDTAVVAYGMATADLPDMDESIHRATRWIVGMQAANGG
YGAFDVDNTYYYLNEIPFADHGALLDPPTADVSARCVMLMAKVAQDHDEYLPAYNRCLDY
IRNEQEEDGSWFGRWGTNYIYGTWSVLIALEHTEIPKNDPMYSKAVTWLKSVQHDDGGWG
EGNQSYHDRSTSGQYHTSTAFQTAWATLALMAAGEHKCKEVQAGIAYLLKSQQQDGLWAD
NCHTSPGFPRVFYLKYHGYDKFFPLWALARYRNEKNSK
>A0A845FDA3|squalene-hopene cyclase|EC 5.4.99.17|Halobacillus litoralis|TrEMBL
MNDRIKDAIKQLEAEIQGRQKDDGCFHFCFENSLMTDANMILLLQTFSKEKELTKQLCER
LSSLQNEEGYWKLYEDDEGNLSATIEAVFALLYAGYYSNGDLAIRKAKAFIRKHGGLNRA
HSMTKITLAIHGQYPWPSLFHLPVHIILLPPSSPVSFYDFSSYARVHMAPVLLLSDQPFV
LKNKQIPDMSDCFFREEEDLLPEASRSLLTSVQSAVKTLTGLPHRLYLLSRQRLLTYMLQ
RIESDGTLYSYFSSTFYMIYALVSCGYQKHDPLIKKAIQGLMQHACLTERGVHIQNSPSD
IWDTALISHALQAHPASGIPLHKSEQFLLKHQQTKFGDWMVAVNHTEPGGWGFSKSNTIH
PDVDDSTAALRALRKDDPSFQSHYTRGLKWVLAMQNDDGGWPAFEIGKTNPLMKFVPIDG
AESASIDPSTADLTGRTLEFLGSNARFPLTDPRIQKAVNWLRSHQEGDGSWYGRWGITYL
YGSWAAITGMRAVGVGKDDPSIRRGVQFLEAVQNEDGGWGESCKSDQEKTYIPLGDSTLP
QTSWALDALMAVHERRTPVIEKGISCVLRKLEEKDWTYEYPTGAGLPGNFYIYYHSYNYI
WPLLVLKKYLSLST
>A0A7W7YNZ3|squalene-hopene cyclase|EC 5.4.99.17|Prosthecobacter dejongeii|TrEMBL
MKLIAALSFALPSLILAQSGTQPARHESLKQEIRLAYDRGLAFLKGKQNNETGQWGDAEP
VAFTALAITSHLLTPGRQPTEPVSAEIEKAYAFLLKNVQPDGGIYVKARANYNTSLALTA
LMLSPKPQNEQTLLAARRFIIGQQNDFDEKGKQDNPFDGGIGYGTPKPNNPAHADLSNTH
FALEALYYSQALLADKGDAGKNEPQLNFGAAIQFIQNCQNRPETNKASWVSTDKADAGGF
VYSPGETRGKDVKTADGRTALRSYGSISYAGMLSFIYAGLDKSDPRVQAVLQWLSENYTL
DENPGLGAEGLYYYYHTMAKALAIADVDFLKTKDGKTVDWREDLASKLLNLQQGDGSWAN
SAGRWMESDTTLTTSYMLMALARVYESL
>A0A7Y0JCZ6|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. GMY02|TrEMBL
MTATTDGSTGATLPTRAAAASEPVLTTPVAAGVHQAAEHAVRRATDFLLSRQDAEGWWKG
DLETNVTMDAEDLLLRQFLGIQDEATTHAAALFIRGEQREDGTWATFYGGPGELSTTIEA
YVALRLAGDAPDAPHMAKAAAWVRARGGIAASRVFTRIWLALFGWWKWEDLPELPPELIY
FPTWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAQPNLVKPLAPAAS
WDGAFQRLDKALHAFRKVAPKRLRRSAMNTAARWIIERQENDGCWGGIQPPAVYSIIALH
LLGYDLQHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPQ
LVKAADWMLGEEIVRPGDWSVRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHHD
PERVDRAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGLAHDPRTRRGIQWLLEEQEPDGSWFGRWGVNYIYGTGSVVPALTAAGLPGSH
PAIRRAVAWLKRVQNDDGGWGEDLRSYRDSKKWSGKGASTASQTGWALMALLAAGERDSE
AVERGVRWLADTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFAA
QAPAGRPLAEAKGS
>A0A7K2Y4C3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID1046|TrEMBL
MRDAARDTARDTARTTADLRRPPDGIRPGVYEAAARATRNLLERQDPEGWWKGDLETNVT
MDAEDLLLRQFLGIRDEATTRAAALFIRGEQREDGTWATFHGGPPELSATIEAYVALRLA
GDAPDAPHMSRASAWIRAHGGIAAARVFTRIWLALFGWWNWDHLPELPPELVFLPPWVPL
NIYDFGCWARQTIVPLTVVSALRPVRPAPFALDELHADARTPYPARRLAPLTSWDGAFQR
MDKALHVYRRFAPRRLRKAAMASAGRWIVERQENDGCWGGIQPPAVYSVIALHLLGYDLG
HPVMRAGLESLERFAVWRADGARMIEACQSPVWDTCLAAIALADAGLRPDHPALVKAADW
MLGEEIVRTGDWAVRRPGLAPGGWAFEFHNDTYPDIDDTAEVVLALRRIKHPDPARIEGA
IARGVSWNLGMQSRNGAWGAFDADNTSPLPNKLPFCDFGEVIDPPSADVTAHVVEMLAFE
GRASDARTRRGIAWLLAEQEPSGGWFGRWGTNYVYGTGSVVPALVAAGMAPGHPAIRRAV
RWLESVQNDDGGWGEDQRSYKDPSWAGKGASTPSQTAWALMALLSAGEREGKAVERGVAH
LVETQKEDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLYGEPFVPAGAQPAPA
GEA
>A0A6A8QFA1|squalene-hopene cyclase|EC 5.4.99.17|Telmatospirillum sp|TrEMBL
ALLSRQQEDGHWVFPLEADATIPSEYVLFLHYMDERDPALEARIGVYLRQIQGAHGGWPL
FHGGDFNISASVKAYYALKAIGDDIDAPHMRRAREAILAHGGAATANVFTRILLALFGQV
PWRAVPVMPVEIMLLPKWFPFHLDKVSYWSRTVIVPLLVLAATKPLARNPLRVDVQELFV
VPPAKVRSWNSEPPRSNWAYFFRGLDVVLQRAQVLFPKSGRRRAIALAEAWVTERLNGED
GLGAIFPAMVNAVLMFDVLGVDPSDPRVVTAKTALRKLVVEEGERAWVQPCVSPVWDTAL
AFHALLEAGDERSMAAARRAADWLVERQGTDVVGDWAAQRPDLAPGGWAFQYANAHYPDV
DDTAVVMAALDRLDGRRYSDAVERGAEWIRGMQSSDGGWGAFDAENTHYALNHIPFADHG
ALLDPPTVDVSARCVSALSVLKPGRADPAVKRGVDYLLAEQEEDGSWFGRWGTNFVYGTW
SALVGLNAAGIPADHPAMRKGAAWLLAHQREDGGWGEDGRSYWDDQPRGEATESTPSQTA
WALLGLMAAGETDNPAVARGVDYLLSHRNGEGLWDEELFTAVGFPRVFYLRYHGYRAFFP
LWALARYRNIRSGNGGPVPHAL
>A0A6A7KVL8|squalene-hopene cyclase|EC 5.4.99.17|Alphaproteobacteria bacterium|TrEMBL
MTAAVEAVVGEADAGSAPSALGAQTMRRLNQAIADCVAGLKKLQKDDGHWVFELEADATI
PSEYVLLHHFLGETDEAIERKIGVYLRQAQGAHGGWPLFHAGEFDMSATVKAYYALKIIG
DDIDAPHMKRARDAILERGGAATCNVFTRIMLALYRQVPWRAIPVMPVEIFHLPRWFPFH
LSKVSYWTRTVIAPLLILMALKPAAVNPRKVDIRELFAVPPEEVGSYLNNPTGSRWGDIL
LWIDSTLRLAEPFFPRAPRRKAIDKAMSFVTERLNGENGLGAIYPAMANTVMAMTALGYP
ADHPDLVVAKDAIEKLLVLDDDRAYCQPCVSPIWDTALVAHALLEAGADGEDPSIRKAMD
WLADKQVLNVYGDWAENRPGVRPGGWPFQYANDHYPDVDDTAVVAMAMQRARPLDYSENL
ARAEEWVIGMQSRNGGWGAFDADNTHFHLNHIPFADHGALLDPPTADVSARCIGMLAQFG
YDRQHPIMRAGVDYLRDDQEEDGSWFGRWGTNYVYGTWSVLCALNAAGEDMSSEYIRRAV
GFLEARQRPDGGWGEDGGTYWNEKRDATKESTPSQTAWALLGLMAAGEVESDAVRRGIEF
LLNAPRKEARWDEDWYTAVGFPRVFYLKYHGYSAFFPAWALARYRRLMQGNSKTVSFGM
>A0A5A9X697|squalene-hopene cyclase|EC 5.4.99.17|Oryzomonas rubra|TrEMBL
MNSSKYPISTALTSFNLETAAPTAPALDPPKKTVAKVHHLPPSIWKKMVGDAKSPLDKAI
ERTRDFFFREQLPDGYWWAELESNVTITSEYVMLFHFLGMVDKVRERKMARYILSKQTEE
GYWAIWHTGPGDLSTTIEAYFALKLAGYPADHPAMRKAREFILANGGIIKARVFTKIFLA
LFGEFSWLGVPSMPIELMLLPNWAYFNVYELSSWARGTIIPLSVVMAERPVRKLPPWARV
KELYVRPLRPTDYTFTKEDGILTWKNFFIGVDHLCKVYESSPIRPFKKKATSVAEQWILD
HQEPTGDWGGIQPAMLNSILALHCLGYANDHPAVVKGLEALANFCIEDEEGLVLQSCISP
VWDTALALVAMQEAGVPADHPALVKAAQWLLDLEVRRKGDWQIKAPELEPGGWAFEFLND
WYPDVDDSGFVMLSIKDIKVRDRKHKEQAIKRGISWCMGMQSQNGGWGAFDKDNTKYLLN
KLPFADLEALIDPPTADLTGRMLELMGNFNYSKSHPAAEHALEFLQKEQEPEGPWWGRWG
VNYIYGTWSVLCGLQAIGEDMSQPYVKKAVNWFKSKQNMDGGWGEVCESYFDRSLMGSGP
STPSQTGWALLALMAAGEVQSKTVARGIDYLLNSQKQDGTWDEDAFTGTGFPKFFMIKYH
IYRNCFPLTALGKYRRLLAESGEKK
>A0A840IQP8|squalene-hopene cyclase|EC 5.4.99.17|Amycolatopsis jiangsuensis|TrEMBL
MTQTVPESTSSTGTAERTAEQTVAAAVGFLRREQHAGGWWKGELATNVTMDAEDLLLRHF
LGILTPQVAEESARWIRSQQRADGTWATFPGGPADLSTTVEAWVALRLAGDPADAPWLST
AAEYVRGHGGLEATRVFTRIWLAMVGQWSWDELPNLPPELVFLPSWFPLNVYDFACWARQ
TIVPLTVVGTLRPARSLPFDVRELRTGKAPAKTRAPWTWDGLFQNLDTALHTYAKLPFNP
VRKVALKQAAEWILARQEADGSWGGIQPPWVYSILALHLLGYPLDHPALKAGLAGLEGFI
IREKTDQGWVRRLEACQSPVWDTALAMTALLDAGVSPGDETLVRAADWVLGEEIRVPGDW
TVRRPTLAPGGFAFEFANDGYPDTDDTAEVVLALRRMGKPDHLRLRGAVDRSVAWLEGMQ
SSDGGWGAFDADNTRELATKLPFCDFGAVIDPPSADVTAHVVEMLAAEGKTEAPECRRGV
RWMLANQEPDGSWFGRWGANYVYGTGAVVPALVAAGIPAGDKRIRRAVRWLADHQNTDGG
WGEDLRSYDDPAWAGRGDSTPSQTAWALLALLAAGQRESEVVTRGVAWLCERQRADGGWD
EDKHTGTGFPGDFYLAYHLYRVVFPLSALGRYVRGGS
>I4FR77|squalene-hopene cyclase|EC 5.4.99.17|Microcystis aeruginosa PCC 9717|TrEMBL
MQIQEKITEIAAKTAKAIELSQNYLLSTQYSDGYWWAELESNVTITSEAILLHKIWKTDK
KRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPANDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWQGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDTGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKAVDNFAIE
TDNTYCVQPCVSPVWDTAWVIRSLIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKAVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYADLKAMIDPNTADVTARVLEMLGTCDVKMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSALAFLEPNQYRQQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A7K2FSM2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4985|TrEMBL
MTATTDGSTGATIPPRRADAASESDSTTPGAAGVPEAAERAVRRATDHLLAGQDPEGWWK
GDLETNVTMDAEDLLLRQFLGIRDEATTHAAALHIRGEQRADGAWATFYGGPGELSATIE
AYVALRLAGDAPDDPHMARASAWVREHGGIASARVFTRIWLALFGWWKWEDLPELPPELI
WFPTWLPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPAHPNPPKPFAPLA
SWDGAFQRLDRMVHKLRRAVPRRLRDAAIGTAARWIVERQENDGCWGGIQPPAVYSVIAL
HLLGYDLEHPVMRAGLESLDRFAIWREDGSRMIEACQSPVWDTCLAAIALADAGLPADHP
QLVKAVDWMLGEEIRRPGDWAVKRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHP
QPARVDGAIGRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAAEGLAHDPRTRRGIDWLLAEQEADGSWFGRWGVNYVYGTGSVVPALTAAGLPAS
HPAIRRAVAWLERVQNDDGGWGEDLRSYKHVTEWSGRGTSTASQTAWALMALLAAGEKDA
KAVERGVRWLAETQREDGSWDEPHFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGDPFD
RAPLATAGGRHAGAEGR
>A0A372GMG5|squalene-hopene cyclase|EC 5.4.99.17|Actinomadura sp. LHW52907|TrEMBL
MTTTEMSGLAGAAAAAAGAARAHLLGLQSPEGWWRGELQTNVTMDAEDLLLRQFLGIRSD
DETRDAARWIRSQQRPDGTWANFHGGPPELSTTVEAYIALRLAGDPVDADHMRRAAAYAR
DAGGIEGTRVFTRVWLALFGQWSWDDLPVMPPEMIYLPARFPLNVYDWACWARQTIVPLT
VLGALRPVRALPFDLPELRGGVRPVKKERGWGRFFEGLDRVLHVYQKRPVRALRAAAIRR
AADWIIARQEADGCWGGIQPPWVYSLMALHELGYGLDHPIIRRGLDGLERFTIRDERGRR
LEACQSPVWDTALAVNALGDAGVPADDPALLRAAAWLAGEEVRGPGDWSVRRPGVPPGGW
AFEFDNDVYPDTDDTAEVILALRKVDFPDAKEPVERAVRWLEGMASRDGGYGAFDADNTR
ELCTKLPFCDFGAVIDPPSADVTAHVVEALCGEGLAESAVVKRAVVWLLRVQEGDGSWFG
RWGANHVYGTGSVVPALVAAGVRRDGPPIRRAVAWLERHQNDDGGWGEDLRSYDDPAWIG
RGESTASQTAWALLALLAAGERSPAVDAGIRWLVDHQRPDGTWDEDRFTGTGFPGDFYIN
YHLYRLVFPISALGRYLSSVQTNGTTELARPKEVRTP
>A0A087PPX6|squalene-hopene cyclase|EC 5.4.99.17|Acetobacter malorum|TrEMBL
MAADGSAHPKTPLSGEDLDRVVQNAHAALGQRQQADGHWVYELEADASIPAEYILLEHYL
NRIDEALEQKIAVYLRRTQSAEHGGWALYHNGGFNLSSSVKAYFALKATGEDINAPHMRR
AREAILDHGGAERTNVFTRIQLALFGDVPWRATPVMPVELMLLPRKAFFSIWNMSYWSRA
VIAPMLVLAALRPIAINPRQIHVRELFVTPPERVTDWIRGPYRSVWGRVFKGLDSVLRPT
LGLIPSKTHEKAITAAIDFIEPRLNGKDGLGAIYPAMANVVMMYRALGVPDTDPRAVTAW
DAVQGLLVHKDDEVYCQPCVSPIWDTGLSGHAMLEAASGPKGIAPEETLTELRKASKWLR
DKQILDVKGDWAVNNPNVAPGGWAFQYGNDYYPDVDDTAVVGMLLHREGDPANNESIERA
RQWIIGMQSRDGGWGAFDIDNSKELLNHIPFSDHGALLDPPTADVTARCISFLAQLGHGE
DRPVMERALTYLRKEQEEDGSWFGRWGTNYIYGTWSALCAFNAAGVSHDDPAVVKAVEWL
RSVQRADGGWGEGCESYEGGSHGTYGESLPSQTAWAVLGLMAAGRRDDPAVTRGISWLAA
QQDENGEWHEDPYNAVGFPKVFYLRYHGYKQFFPLMAVARYRNLESSNTRRVAFGF
>A5EBP6|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)|TrEMBL
MTVTSSASARATRDPGNYQTALQSTVRAAADWLIANQKPDGHWVGRAESNACMEAQWCLA
LWFMGLEDHPLRKRLGQSLLDSQRPDGAWQVYFGAPNGDINATVEAYAALRSLGFRDDEP
AVRRAREWIEAKGGLRNIRVFTRYWLALIGEWPWEKTPNIPPEVIWFPLWFPFSIYNFAQ
WARATLMPIAVLSARRPSRPLPPENRLDALFPHGRKAFDYELPVKAGAGGWDRFFRGADK
VLHKLQNLGNRLNLGLFRPAATSRVLEWMIRHQDFDGAWGGIQPPWIYGLMALYAEGYPL
NHPVLAKGLDALNDPGWRVDVGDATYIQATNSPVWDTILTLLAFDDAGVLGDYPEAVDKA
VDWVLQRQVRVPGDWSMKLPHVKPGGWAFEYANNYYPDTDDTAVALIALAPLRHDPKWKA
KGIDEAIQLGVDWLIGMQSQGGGWGAFDKDNNQKILTKIPFCDYGEALDPPSVDVTAHII
EAFGKLGISRNHPSMVQALDYIRREQEPSGPWFGRWGVNYVYGTGAVLPALAAIGEDMTQ
PYIGRACDWLVAHQQADGGWGESCASYMDVSAVGRGTTTASQTAWALMALLAANRPQDKD
AIERGCMWLVERQSAGTWDEPEFTGTGFPGYGVGQTIKLNDPALSQRLMQGPELSRAFML
RYGMYRHYFPLMALGRALRPQSHS
>V5C8M3|squalene-hopene cyclase|EC 5.4.99.17|Methyloglobulus morosus KoM1|TrEMBL
MLTETSSPSSLDTAFTGIAYSTSTLDSAIAKAKVPLLGMQHEAGYWVFELEADCTIPSEY
ILMMHFMDEIDEVIQVKIANYIRSQQNADGSYPLYKGGTGDISCTIKAYYAMKMAGDAVN
ATHMVKAREWILGKGGAAKGNVFTRIMMAMFGQIPWRGVPYMPVEIMLLPKWFPFHLDKV
SYWSRTVMVPLFILCTYKVKARNPHNIGIAELFVIPPDEERNYFAHVKTPLGKTILIAER
IGRLMEPLIPSLIRRRATGKARDWFLERLNGYNGLGAIFTAMVNAYLAMDYLGIPVDNEQ
RQVARAAIDRLLVIKDDMAYCQPCVSPIWDTGLSSLVLQEVDRYESNPQTQKAIRSALHW
LAAKQLKDEPGDWQNRRPNLPGGGWAFQFGNSYYPDVDDTAVVALAMVQADNRKFAENIG
RAGIWIAGMQSTNGGYGAFDADNTHHYLNHIPFADHGALLXPPTADVSGRCVMFLAKIVN
QHPEYQTVIDNCIAFLRKEQETDGSWFGRWGTNYIYGIWSVLIGFETAGVPRNDPSIRKA
VTWLKSKQRADGGWGEDNYSYHGKNIRGVFHTSTAFHTALALLALLSAGEVGCVEVESGV
NYLLKNQQSDGFWKDKSFNAPGFPKVFYLKYHGYDKFFPLWALARYRNECLTVG
>A0A1W1HSG0|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp. ND1|TrEMBL
MRLLKNLFNRLSDSLLVSVPSRIRAARDFASAPVLRLVSNKSAVPASGDSAAKRAPAHST
GQVEALEEALRKSQAWFLARQDASEGYWVAELEADTTLTSEYLMLRRFLDCIDPERERKA
VRYLKSAQLPDGGWSIYHGGPAEISASVKAYFALKLSGVSADEPFMVNARTCILDKGGVV
AANVFTKIALALFGQYDWRGVPSMPPEIMLLPKRFYFSIYAISYWSRAVLIPLLIIFAKR
PLCHVPPELGIDELYTEPPAEIDYGMVPPFKKDRTWFTARNFFINLDALLKIYDRSPVEW
VRQKALKCAENWMLDHMKGSGGLGAIYPAMANSVMALHCLGYKNDDPLMVKAIREIEELE
VHDTVQDNGQCVDAMHLQPCHSPIWDTALLINALIEAGMPQDHPALQKASTWLLSKQTKT
VGDWIISAPGAEPGGWYFQFENELFPDVDDSAVVLMALAKVHLSDEAQQRLAIRRGCRWV
TSMQGSDGGWGAYDVDNNRIVFNYIPFADHRALLDPSTADLAGRCLEMLATLGYDWTHPA
VASALTFVKNDQEQDGSWYGRWGVNYIYGTWSVLSGLRAIGEDLSSPYIRRAVSWVESKQ
NPDGGWGESCLSYGDVSQSGRGDSTPSQTAWALLALMAGGVTDSFSLARGIHYLIRNQRK
DGSWEEVRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLKTRGTTRADELRLQAYQSGQ
FRSPR
>A0A857FSG6|squalene-hopene cyclase|EC 5.4.99.17|Komagataeibacter xylinus|TrEMBL
MNSESRLSRKQAGTPGPDKTESRPDSAPAAAFRGIDNSLTHTISAACKWLMEQQKPDGHW
VGSVASNASMEAEWCLALWFLGLEDHSLRPRLGKALLEMQREDGSWGIYYGAGNGDINAT
VESYAALRSLGYAADDPALSRAATWIASKGGLRNVRVFTRYWLALIGEWPWEKTPNLPPE
IIWFPNKFVFSIYNFAQWARATLVPLAILSARRSSRPLRPQDRLDALFPAGRENFDYELP
PRDGQDLWATFFRKTDRALHWLQTKFLKRNTMREAAIRHMLEWIIRHQDADGGWGGIQPP
WVYGLMALHGEDYQFHHPVMAKGLAALDDPGWRYDRGDASWVQATNSPVWDTMLALMALH
DADAETNFSPEMDKALGWLLERQVRVKGDWSVKLPDLEPGGWAFEYANDRYPDTDDTAVA
LIALAACRDREEWKGRGVEAAITRGVNWLVGMQSTCGGWGAFDKDNNRALLSKIPFCDFG
EALDPPSVDVTAHVLEAFGVLGLPRDMPALQRGLAYIRAEQEADGPWFGRWGVNYLYGTG
AVLPALAAIGEDMTQPYIAKACDWLVAHQQENGGWGESCASYMEIASIGRGPTTPSQTAW
ALMGLIAANRKQDHEAIVRGCRYLIDLQQPDGRWDEKEFTGTGFPGYGVGQTIKLDDPAL
TSRLQQGAELSRAFMLRYDLYRQFFPIMALSRASRLLKSST
>A0A7L5T324|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. Rer75|TrEMBL
MTATTVQPSESSESETLVLARKATARAVQHLLSRQDEQGWWKGDLETNVTMDAEDLMLRH
FLGIQNPDVLDAAGRYIRAQQAADGTWATFHGGPPELSATIEAYVALRLAGDAPDAPHMA
AASAWVRNNGGVANSRVFTRIWLALFGWWRWEDLPELPPEIIYFPSWLPLNLYDFGCWAR
QTIVPLTIVSAKRPVRPAPFSLDELHADPRRPDPPRPAAPLASWDGAFQRLDRALHLYRK
VALRPLRRAALRSCARWIVERQENDGCWGGIQPPAVYSVIALHLLGYDLDHPVMRAGLES
LDRFAVWREDGSRMIEACQSPVWDTCLAVIALADAGLAPDHPALVKSADWMLAEQIHRPG
DWSVKRPRLAPGGWAFEFDNDNYPDIDDTAEVILALRRVDHPHPERIAAAVRRGVRWTLG
MQSRNGAWGAFDVDNTSPLPNRLPFCDFGEVIDPPSADVTAHVVEMLAHEGGARDPRTRR
AVGWLLAEQEPSGAWFGRWGTNYVYGTGSVVPALVAAGIPATHPAIRRAVRWLESVQNED
GGWGEDQRSYTDPEWIGHGTSTASQTAWALLALLAAGERESKAVERAVGWLAATQDQDGS
WDEPYFTGTGFPWDFSINYHLYRHVFPLTALGRYVSGEATGARPRRT
>A0A7V8KXL1|squalene-hopene cyclase|EC 5.4.99.17|Burkholderia pseudomallei|TrEMBL
MNDMTEMHTLDATAAPAGLDAAVARATDALLAVQQADGHWVYELEADSTIPAEYVLLVHY
LGEAPNVELEQKIARYLRRIQQPDGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPVAKNPRGVRIDELFKGAPVSTGLLPKQPHQSAGWFAFFRAVDGVLR
LVDGLFPRYTRERAIRQAVAFVDERLNGEDGLGAIYPAMANAVMMYAALGYPEDHPNRAI
ARRSIEKLLVVGEQEAYCQPCLSPVWDTSLAAHALLETGDARAREAAVRGLDWLVPRQIL
DVRGDWISRRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLDRTDAYRESIARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTADVSGRCLSMLAQFGETSA
SSEPARRALDYMLKEQEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHDDPRVKRAAQWL
LSIQNADGGWGEDGDSYKLDYRGYERAPSTSSQTAWALLGLMAAGEVDNPAVARGVDYLL
GTQREHGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATHVTVGM
>A0A8J7ABK6|squalene-hopene cyclase|EC 5.4.99.17|Desmonostoc muscorum LEGE 12446|TrEMBL
MQTQDRVKVKQIAEAIAASQEYLLSIQNPAGYWWAELESNVTITAEVVLLHKIWETDQTR
PLHKVADYLRQEQREHGGWELFYGDGGELSTSVEAYMALRLLGVPANDPALVRARKFILQ
RGGISKTRIFTKLHLALIGCYNWRGIPSLPPWIMLLPKAFPVNIYEMSSWARSSTVPLLI
VCDRKPIFLTDGAINLDELYVESVDRVQWGLPRNNDWTDLFLTLDDGFKLAEHLNLVPFR
AEGIKAAEKWILERQEVTGDWGGIIPAMLNSMLALRCLGYDQNDPIVERGLQAIDNFVIE
TEDSYRVQPCVSPVWDTAWAMRALVDSGFAPDDPAVVRAGEWLLEKQILDYGDWAVKNRQ
GKPGAWAFEFDNRFYPDVDDSAVVVMALHQAKLPNEKIKQGAIARALKWIASMQCKPGGW
AAFDLDNDQDWLNSIPYGDLKAMIDPNTADVTARVIEMLGGCNLSIEPHNLERALSYLLG
EQETEGCWFGRWGVNYIYGTSGVLSALALIDPQKHKLNIERGATWLLGCQNPDGGWGETC
RSYDDPSLKGKGNSTASQTAWALIGLLAAGEATGKLALEAIERGIAYLVTTQQPDGTWFE
ADFTGTGFPCHFYLKYHMYQQYFPLIALGRYQAAIRKD
>A0A6I5FRL3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID8374|TrEMBL
MTATTDGSTGAANLSASPAGHPADTTTAADDVLAAARRAAERSVAHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDPETTRAAALFIRGEQLGDGTWNTFYEGPSDLSATIEAY
VALRLAGDRPDEPHMARASAWVREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFF
PKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPAEPSPPRKLAPAASW
DGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIVERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVMKAGLASLDRFAVHREDGARMVEACQSPVWDTCLATIALVDGGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARLEAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLGSHPRTRRGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALVAAGLPAAHP
SIRRAVTWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDSRAV
ARGVTWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVYGDPFADRT
GAAKGA
>A0A7W4J7G8|squalene-hopene cyclase|EC 5.4.99.17|Gluconacetobacter johannae|TrEMBL
MMPNATDTLDLSRPAARDPIVPMADIDRATDRAHAALGRRQNDDGHWVFELEADATIPAE
YVLLEHYLDRIDPALQARIGVYLRRIQGEHGGWPLYYGGKFDISASVKAYFALKAIGDDI
NAPHMARARAAILDHGGAERSNVFTRFQLALYGEVPWHATPAMPVELVLLPRKAFFSMWN
MSYWSRTVIAPLLVLAALRPRALNPRGVHVPELFVTPPSRIHDWIRGPYRSPLGRVFKYV
DKLVRPAERLIPEATRRRAIKAAVDFIEPRLNGVDGLGAIYPAMANTVMMYRALGVPDSD
PRAATAWEAVRNLLVENGEETYCQPCVSPIWDTGLAGHAMIEAASGPEGVRPEETRQKLA
AAAGWLRDRQILDVKGDWAINCPDVAPGGWAFQYRNDHYPDVDDTAVVGMLLHREGDPAN
DEAIERARQWIIGMQSSNGGWGAFDIDNNLEFLNHIPFADHGALLDPPTADVTARCISFL
AQLGHPEDRPVIERGIAYLRSDQEKEGCWFGRWGTNYIYGTWSVLCAYNAAGVAHDDPSM
VRAVEWLRAVQREDGGWGEDCASYEGATPGIYHESLPSQTAWAVLGLMAAGQHGDPAVAR
GMAFLTRMQNADGEWDEEPYNAVGFPKVFYLRYHGYRQFFPLMALSRYRNLASSNSRHVA
FGF
>A0A371WHQ8|squalene-hopene cyclase|EC 5.4.99.17|Methylovirgula sp. 4M-Z18|TrEMBL
MMPSSGETDELAQPLVSELELAVDRGREALKACQDADGHWLFELEADATIPAEYILLRHY
RAEPDDLELERKIAVYLRRIQGAHGGWPLFEGGALDISASVKAYFALKMIGDTPDMPHMQ
RARAAILVHGGAARSNVFTRILLALYQAVPWRAVPVMPVEIMLLPRWFPFHLSKISYWAR
TVIVPLLILQALKPIAKNPRGVGIEELFVVPPDRVRHWPKGPHQKAPYAQIFAGIDRALR
LVEPLFPRRPRERALAKAEAFILERLNGEDGLGAIYPAMANAVMAFDVLGYKADDPALGI
ARHAIDKLLIVTENEAYCQPCVSPVWDTALACHALLEADGGEGAALAHQGLAWLKPRQIL
DVKGDWAVQRPALRPGGWAFQFANDHYPDLDDTAVVVMAMDRAQNASNHRDFADAIARGR
EWVEGLQSRNGGWSAFDADNDYEYLNHIPFSDHGALLDPPTADVTGRCLSMLGQLGETEA
SSQSVRQALAYLWLDQRKDGSWYGRWGVNYVYGTWSVLCGLNAVGLDAQTPQIRKAVDWL
IAIQNPDGGWGEDCSSYRLDYAGYQPAASSASQTAWAVLGLMAAGEGQHTAVARGVQWLL
DRQTDNGFWKEDHYTGTGFPRVFYLRYHGYAKFFPLWAVARYRNLQKGNSARVLHGM
>A0A6B2W2S9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID13666|TrEMBL
MTATTDGSPGAPAPQAPSASTTSAPHPVHVGGAEAAAERAAQRAAANLLAAQHPDGWWKG
DLETNVTMDSEDLLLRQFLGIQDERTTQAAARWIRSLQRDDGSWPTFHSGPGDLSATVEA
YVALRLAGDTPEAPHMANASAWVREAGGVVGARVFTRIWLALFGWWRWEDLPELPPEIIY
LPKWFPLNIYAFGCWARQTIVPLTVVAAHRPVRPAPFGISELHKDPAQPNPPRPPAPLAS
WDGLFQRLDRALHLYRKVGVRPLRRTALKACARWIIERQEDDGCWGGIQPPAVYSVIALH
LLGYELDHPVVRAGLDSLDRFAVWPDEDTRMIEACQSPVWDTCLATIALADAGVATDHPA
LVKAVDWMLDEQITKPGDWAVQRPGLQPGGWAFEFHNDNYPDIDDTAEVVLALLRVQHPD
PGRVDAAVEKAVRWNIGMQSKNGAWGAFDADNTSAFPNRLPFCDFGEVIDPPSADVTAHV
VEMLASLGLEDDTHTRRGIDWLLAEQEDSGAWFGRWGVNYIYGTGSAVPALVAAGLPVSH
PAVRRAVGWLESVQNQDGGWGEDLRSYSDQEWIGRGVSTASQTAWALLALLSAGERDSDA
VERGVRWLVDTQKADGSWDEPYFTGTGFPRDFSINYHLYRMVFPLTALGRYARSEPLGVI
GNVTKGKAAG
>A0A7H8ZJ23|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. CB04723|TrEMBL
MTATTDGSTGAANPARATAHGPTDTTTSADDVTAAARRAAERSVEHLLGRQDEQGWWKGD
LATNVTMDAEDLLLRQFLGIQDADTTRAAALFIRGEQLGDGTWNTFYGGPSDLSATIEAY
VALRLAGDRPDEPHMARAAGWIREQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFL
PTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPDRPSPPRKLAPPTSW
DGLFQRLDKGLHLYHKVAPRPLRRIAMNVAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLDHPVMKAGLDSLDRFAVRREDGARMVEACQSPVWDTCLATIALADAGLRPDHPAL
VKAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPDP
ARVEAAIARGVRWNLGMQSRNGAWGAFDADNTSGFPNRLPFCDFGEVIDPPSADVTGHVV
EMLAVEGLARHPRTREGIEWLLAEQEACGAWFGRWGVNYVYGTGSVVPALIAAGLPAGHP
AVRRAVSWLESVQNDDGGWGEDLRSYQEEKWIGHGESTASQTAWALLALLAAGRRDTPSV
ARGVRWLTEAQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRFVHGDPFADRA
DAVEGA
>A0A7K3G2K8|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID5770|TrEMBL
MTATTDGNAGAVSPRTAVAGKTTDTALPEGPDPVPGRLDETAARAAARAAEHLLARQDPA
GWWKGDLETNVTMDAEDLLLRQFLGILDPDTTRAAALHIRREQREDGAWATFYGGPGEVS
ATVEAYVALRLAGDRPEAPHMARASAWVRARGGIAAARVFTRIWLALFGWWRWEDLPELP
PELLFLPKWFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPLDELHTDPARPNPPRPL
APVTGWDGLFQRLDKALHLYHRVAPRPVRKVAMDLAARWIVERQENDGCWGGIQPPAVYS
IIALHLLGYDLGHPVMRAGLESLDRFAVRREDGSRMVEACQSPVWDTCLATIALADAGLP
PDHPALVKAVDWMLDEEITRTGDWAVRRPGLPPGGWAFEFHNDNYPDIDDTAEVLLALRR
VRHPDPARVEGAVARGTRWTLGMQSRNGAWGAFDADNTSPFPNKLPFCDFGEVVDPPSAD
VTAHVVEMLAHEGLSQDPRTQRGIEWLLAEQEPHGAWFGRWGVNHVYGTGSVLPALAAAG
IPASHPAVRRAVAWLGSVQNEDGGWGEDLRSYDDEQWVGRGASTASQTAWALIALLAAGE
RETEPVRRGVAWLAATQLPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYAYGE
PSPRKEG
>A0A840VF25|squalene-hopene cyclase|EC 5.4.99.17|Haloferula luteola|TrEMBL
MKQLLVSTLGATALVASALPAAAQDAPPNPYLSLQQEMKLAIARGNEWLAQQQKEQGWWD
TEDLPALTALALTAAVRDPAVDPAKELPESIAKGFEWLKEQQKEDGGIYNKGLGVYNTAT
SVTALTAGGRDVDEPAIVRGRKYLIGEQWDIGKAKETDNANDGGIGYGSHNDHTDLSNTY
LAIEALALSKQVVDDGNFGDQPDLDWDAAITFLSRCQNLEATNDQEWASDDEQNKGGFIY
TPGDSKAGEVELPDGRTALRSYGSISYAGLLSLVYAKLEPNDARVVAVKEWAGKNWTLDE
NPGMGLQGLYYYYQAMSKALAAAKVDKLPLADGKAVDWRSDLAGKLLATQKSDGSWINEN
GRWMESNPILVTSYTVMALEQIYHSIPGKP
>A0A7C3JW07|squalene-hopene cyclase|EC 5.4.99.17|Chloroflexi bacterium|TrEMBL
MSDQSAFAQLVEQDLAVIHRRRDAHAPPREAVEEAVIRACDWLLQRQQEDGHWVGELEGD
SILETEYVLLLHFLGKADPEKVRRLCAYVLNHWQGPDGGMPIYPGGPSDVSASVKAYFAC
KLARIPPDDPRMERLRECILRMGGVTRCNTFTKLYLSIFGQYDWEGVPTIPPEIVLAPRW
AYFNIYEMSSWSRAILVPLAIINACRPRRPVPPECAIDELFVGGRHGRHLRLPWDSRPVT
WRNAFLLADRVLKVYDRSPVKPLRRRALKLAEQWLLERQRGSGGLGAIFPAMVHAIMAFK
CLGYPDDHPAIQHELRELHRFEIEEDGETRLQPCVSPVWDTALALNALLDAGVPASDAAI
SKGVDWLLGVQTSAPGDWAVKAPGLEPGGWFFEYANEFYPDVDDTVMVLMALYKAACPQG
EPWTSAPPRVRAAMERGLNWVLGMQNRDGGWASFDRNNDRMVFQYMPYADHNAMLDPSTA
DITARVLECLSFYGIGAEDPRVRRALGYLKREQEEDGSWFGRWGVNYL
>A0A520RMI2|squalene-hopene cyclase|EC 5.4.99.17|Verrucomicrobia subdivision 3 bacterium|TrEMBL
MKEPLFSPLNKEAFWITIQRSQDYLLNAQLPDGYWQGELRIDCTLVADTICFKHWDGKVD
EVWQRKAVNHLLNLQLPEGGWNIYHGGPAEVNATIKSYLALKLAGLKEADPRMSRARSVL
LNLGGVPRMNTFSKLYLALLGLFPWKYLPTIPCEVILIGNWFYLNFHEMSNWTRSIIVPL
SIINHFKPTRKLRHPVTIDELYPDGFHERDLRLPHSPEIFSWRNLFLAMDKVNKLAEKFA
QWGIHPFRRQALRKSEDWMLERFEGADGLGAIWPSMLNSLIAMKAMGYEDDHPQVLRAER
ELKKLEHETETEVRIEPCLSPVWDTAIACAALSASGVAPANPIMRKAADYLVSKEIRFRG
DWKYKNEADIEPSGWAFEHENKWSPDVDDSAMVMLALRRMQSSDKKAQQACLKRGLEWLL
TFQCKGGGWAAFDKDCTKSIMEKVPFADHNAMLDPECADITARILELLGAEGLTLEHPQV
KLGVQYLRSQQEEDGSWYGRWGVNYLYGTWLALRGLRALKMDMHQPWLQKAKDWLESVQL
IDGGWGERCNSYEDPVLKGQGPSTASQTAWAVMGLCAFGDPGLPSLHRGIQYLIDMQSND
GSWPEEETTGTGFPLVFYLKYDMYRNSWPLLALATYQDLVKAKANASL
>A0A328IEA9|squalene-hopene cyclase|EC 5.4.99.17|Hapalosiphonaceae cyanobacterium JJU2|TrEMBL
MQIQDRVTASKVPDAIAASQKYLLSIQKPQGYWWSELESNVTITAEVVLLHQIWGTDKSR
PLHKVEAYLRSQQREHGGWELFFGDGGELSTSVEAYMALRLLGVPPTDPAMIKARRFIVE
RGGISRTRIFTKLHLALIGCYSWQGVPSLPPWVMLLSQNFFFNIYEMSSWARSSTVPLLI
VCDRKPVFRVDPAFNLNELYAEGIEKVKYELPRNGNWGDIFLTLDSGFKLAENLNLVPFR
TEGIKAAEKWILERQEATGDWGGIIPAMLNSLLALRCLDYNPADPIVERGLQAVDNFAIE
TADTYQVQPCVSPVWDTAWAIRALVDSGLSPNHPAVVQAAEWLLSKQILDYGDWAVKNRQ
GKPGGWAFEFDNRFYPDVDDTAVVVMALNQVELPNEKLKHQAMVRAVDWVASMQCKPGGW
AAFDLDNDQDWLNQIPYGDLKAMIDPNTADVTARVLEMLGSCQLSIDTENQQRAIKYLLN
EQESEGCWFGRWGVNYIYGTSGVLAALSLVAPQTHRHNIEQGATWLVSCQNSDGGWGETC
RSYDDPSLKGKGRSTASQTAWALIGLIAAGRATGNFAKLAIEQGIDYLLITQLPNGSWDE
ADFTGTGFPSHFYLKYHLYQQYFPLIALGQYQKLFA
>A0A7Y2SF69|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. PKU-MA01144|TrEMBL
MTATTDGSGGAPALRSPSASDHTTDHRPAPGDSAGLCTTALLTAQRSVEHLLGRQAPQGW
WKADLETNVTMDAEDLLLRQFLGVHDEKTTAAAAVFIRGEQREDGTWATFYGGPGELSTT
IEAYVALRLAGDRPDDPHMERAAAWIRARGGIAASRVFTRIWLALFGWWKWEDLPELPPE
LIYLPSWFPLNIYDFGCWARQTIVPLTVVSATRPVRPAPFALDELHTDRHRPNPPRPLAP
AGSWDGVFQRLDRLLHGYRAVALRPLRRAAMNRAARWIIERQENDGCWGGIQPPAVYSLI
ALHLLGYDLDHPVMRAGLESLDRFAVWREGTAGPGDRREGPARMVEACQSPVWDTCLTVV
ALSDAGVPADHPALVRAADWMLGEQITRPGDWAVRRPRLAPGGWAFEFHNDNYPDIDDTA
EVVLALRRVKHPDPARVEEAVARAGNWTLGMQSKCGAWGAFDADNTGTFPNRLPFCDFGE
VVDPPSADVTAHVVEMLAQEGRAHHPRTRRGVDWLLREQEPHGAWFGRWGVNHLYGTGAV
VPALTAAGVPVSHPAIRRAVGWLESVQNDDGGWGEDLRSYREESWIGRGVSTPSQTGWAL
LALLAAGERDGSAVERGIAFLAATQREDGSWDERYFTGTGFPWDFSINYHIYRQVFPLMA
LGRYVHGQPPAGRNGD
>A0A7K2LEU7|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. SID4920|TrEMBL
MTATTDGSTGAVDPRAASASRPTIESTIAADGVPAAARRAAERSVEHLLGRQDEQGWWKG
DLATNVTMDAEDLLLRQFLGIQDPATLRAAAGFIRGEQLGDGTWATFHGGPADLSTTIEA
YVALRLAGDRPEDPHMARAAGWVREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELMF
FPPWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPDRPNPPKRPAPAAS
WDGLFQRLDKALHVYHRFAPRGLRRVAMNAAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLEHPVMRAGLESLDRFAVWREDGTRMIEACQSPVWDTCLATIALADAGLAPDHPA
LVKAADWMLAEEIVRPGDWAVRRPRLEPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHPD
QARVDAAIERGVRWTVGMQSRNGAWGAFDADNTSPFPNRLPFCDFGEVIDPPSADVTGHV
VEMLAIEGRAADPVTRRGIEWLLSEQDPAGGWFGRWGVNYVYGTGSVVPALVAAGLPPAH
PSIRRAVEWLESVQNDDGGWGEDLRSYSEEKWIGQGASTASQTAWALLALLAAGRRDTVA
VTRGIAWLTETQQADGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGDPFADR
TPMREGA
>A0A532D6V3|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp|TrEMBL
MKLIRTLLDRLSDSFFISAPEKLGLATEPSNIHPLRLVSDNSMPNVSIDAVTRRSTSHSV
SQVDALDDAVRRSQAWFLSKQHASEGYWVAELEADTTLTSEYLMLRRFLDRVDPERERKA
VHYLRAMQLPDGGWPIFYGGPSEISASVKAYFALKLSGVSASETFMLRARDRILAMGGVV
CANVFTKITLALFEQYDWKGVPSMPPEIMLLPRRFYFSIYAISYWSRAVLIPLLIVFANQ
PVCRIPKEQGIDELYLAPRSEIHYRDVPPFNKDQRWFTPHNFFVQLDRVLKLYDTMPLNW
LREKSLQKAATWMLEHIKGSGGLGAIYPAMANSIVALRCLGYQVDDPLVQKSLREIELLE
VYSPVSIGDQRVEALHLQPCHSPIWDTALLMNALIETGLPQDHQALQKAGEYLVSRQTKT
VGDWKFSSPDAEPGGWYFQFENEFYPDVDDSAVVLMALSKVRLDQPVELQESIRRGMNWV
LAMQGSDGGWGAYDKDNNRVVFNYIPFADHHALLDPSTSDLTGRCLEMLAALGYDQTHPA
VGPALRFLKREQEADGSWYGRWGVNYIYGTWSVLAGLHAIGVDLSEPYVLRAVAWLESKQ
NPDGGWGESCLSYHDDPEWSGKGESTPSQTAWAIMGLMSAGMVDAFSVARGVQYLLRQQM
KDGSWEEVRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRTRGKMRADEVRQQVLASG
CYRADR
>A0A8G0W6M7|squalene-hopene cyclase|EC 5.4.99.17|Sphaerospermopsis torques-reginae ITEP-024|TrEMBL
MQTQDRVKVKEITEAIAASQQHLLSIQKPDGYWWAELESNVTITAEAVLLHKIWGTDKTR
PLHKVKNYLRSQQKEHGGWELFYGDGGELSTTVEAYMALRLLGVPATDPALIKAKSLILQ
KGGISKTRIFTKLHLALIGCYNWRGLPSLPPWVMLLPENFPFNIYELSSWARSSTVPLLI
VFDQKPVFEIDSPINLNELYTEGVNNVKWELPKNNDWSDIFTILDDGFKLAESLNFVPFR
EEGIKAAEKWILDRQEATGDWGGIIPAMLNSLLALKCLDYDANDPIVYRGLKAVDNFAIE
TENNYCVQPCVSPVWDTAWAIRALIDSGFEADYPVIVKAGQWLIDKQILDYGDWFVKNKQ
GKPGAWAFEFDNRFYPDVDDSAVVVMALHQAKLPHENLKKQAIKRALNWIASMQCQPGGW
AAFDIDNNQEWLNAIPYGDLKAMIDPNTADVTARVIEMLGACNLSIPADKLEKALNYLLN
EQETEGCWFGRWGVNYIYGTSGVLSALALINPQKYRSEIERGAAWLVKVQNADGGWGETC
FSYNDPSLKGKGDSTASQTAWAIIGLIAAGEATGKFDFQSLEKGVNYLLETQSSDGTWDE
SYFTGTGFPCHFYLKYHLYQQYFPLIALGRYSRI
>A0A563VS53|squalene-hopene cyclase|EC 5.4.99.17|Hyella patelloides LEGE 07179|TrEMBL
MQTEYQLTFPQKVEQAIAASQKYLLSIQYPDGYWWAELQANVTITSEVLLLHKIWGTDRS
LPLEKIEYYLRSQQQDRGGWELFYGDGGELSTSVEAYMALRLLNVPANDPALVKAKKFIL
QRGGISKTRIFTKFHLALIGCYDWEGIPSIPPWLMLLPEDGIFSIYDLSSWARGSTVPLI
IVFDQKPVFVVDPIVNLDELYTEGIDSVKYELPRNDDWTDIFVELDNVFKLAENLRLVPL
RQEGLKVAEKWILERQEATGDWGGIIPAMLNSLLALRCLNYDVADPIVERGFAAFDNFAI
EKEDSFYMQSCISPVWDTAWCLRALVESGIQPNHPALVRGGKWLLDKQILDYGDWQVKNK
TATPGGWAFEFDNRFYPDLDDSAVVVMALNDVVLPNEDVKQKAIARCLNWMTSMQCKSGG
WAAFDLNNDKDWLNLLPYSDLKATIDPDTADVTARILEMIGQCHLPMKYSRVKSAISYLL
DEQEVDGSWFGRWGVNYIYGTSGVVSGLALMAPEICEDNINRGAKWLVSCQNEDGGWGET
CFSYNDPNLKGQGDSTASQTAWALIGILAAVEATGFAATEALKRGVEYLVTTQQDDGSWN
EEYFTGTGFPGHFYLKYYMYQQYFPLLALGRYEKFFKGTG
>A0A849AJ82|squalene-hopene cyclase|EC 5.4.99.17|Flexivirga aerilata|TrEMBL
MTETLVGTTASEDTAAGRARTTADRAIAYLRGLQLPSGAWKGELETNVTMDAEDLMFRTL
LGIDTAETREQTARWIRSQQRADGTWGIYYGGPGELSTTVEAWIALRLAGDKPTAEHMVA
AREFILAAGGLERTRVFTRIWCAMFGWWDWRDLPNLPPELMLLGKRVPLNIYDWGCWARQ
TIVPLTVIGTLRPTRRMPWNLDELRTGATRREAEPAGGIAGVFQRLDTALHAYGKHPVGP
LRRASLRLAAEWILARQEADGCWGGIQPPWIYSVLALHALGYPLDHPVLKTAIDGLEGFV
ITEDTADGRVRRFEACQSPVWDTALTLNAFLDAGVDPRDEAIRKAADWLVGEQITTPGDW
AVRRPSLPPGGWAFEYANDNYPDTDDSAVIVMALNRVISHRQPLVDRAVSRGIAWTAGMQ
SKDGGWGAFDADGTAKLPGKLPFCDFGAVTDPPSADVTAHVVEMLAAVGRQGGARCKRGV
RWLLDHQEADGSWFGRWGANHLYGTGAVVPALVAAGVPVTDPAIRAARRWVVAHQNDDGG
WGEDVRSYADPAWIGRGESTPSQTAWSLLALVAAGELGPPLTRGIDYLAKTQRPDGGWDE
AMFTGTGFPRDFYIAYHLYRQIFPIWALGRAVTALRGGERGDRPTLELV
>A0A6G7SRG2|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces sp. ID38640|TrEMBL
MTATTDGSTGALPPRAPSASDATAENTAPPAATRTAVRQDTVDAARRATARATDYLLSVQ
DPAGWWKGDLETNVTMDAEDLLLRQFLGIQDPELTAAAARHIRSEQCADGTWATFYGGPG
ELSATIEAYVALRLAGDAPDAPHMAKAAAWVRGQGGIAAARVFTRIWLALFGWWKWDDLP
ELPPELLYFPKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELHTDPRRPNPP
RPLAPATSWDGVFQRLDKALHLYHKVAFRKLRAAAMRSAARWIIERQENDGCWGGIQPPA
VYSIIALHLCGYDLDHPVLRTGLASLDRFAVWREDGPPGPDGPGGAPTRMIEACQSPVWD
TCLATIALADAGLPADHPQLVKAAEWMLAEQIDRPGDWSVKRPQLPSGGWGFEFENDNYP
DIDDTAEVVLALRRVQHPDPLRVEAAVRRAVRWNLGMQSKNGAWGAFDVDNTSPFPNRLP
FCDFGEVIDPPSADVTAHVVEMLADVGRTHDPRTRRGIAWLLAEQESSGAWFGRWGTNYL
YGTGSVLPALAAAGVPASHPAVRRAVRWLERVQNDDGGWGEDQRSYQDKEKWAGRGASTA
SQTAWALMALLAAGERGSEAVRRGVHWLTATQREDGSWDEPYFTGTGFPWDFSINYHLYR
QVFPLTALGRYLNGGPAGAPVGA
>A0A525W159|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira sp. CG24B|TrEMBL
MNIIKALFNRLSDSLLSTVQGRLDPATELTPVASLRLVSDKPVILASLDSSAARRPIGHA
VSQPDAVDDAIRRSQSWFFNRQHAEGYWVAELEADTTLTSEYVMLRRFLDRVDPAREVKA
VRYLQATQLQDGGWPIYYGGPAEISASVKAYFALKLCGVSPDEPFMVCAKERILAMGGVL
QANVFTKITLALFDQYDWEGVPHMPVELMLLPKKFYFSIYAISYWSRAVLIPLLIVFAHR
PVCRIPREQGIDELYPIPRPEVRYWKYPPFNKDQAWFTPHNFFVALDVMLKLYDRMPMRA
LREKALHKAACWMVDHLKGAGGLGAIYPAMANSIMALQCLGYDADDPLVVKALREIEALE
VYDSTMVDGESVPTLHLQPCFSPVWDTALLMNALVEAGVPQDHPSLQKAGRYLMSRQTKA
VGDWIISSPNAEPGGWYFQFENESYPDVDDSAVVIMALSKLKFPGHEDELNESIGRGMRW
VLAMQGSDGGWGAYDKDNNRVVFNYIPFADHKALLDPSTSDLAGRCLEMLGALGYDKTHP
AAGPALAFLKKEQEKDGSWYGRWGVNYIYGTWSVLAGLRAIGEDLSAPYIRRAVAWLESK
QNPDGGWGESCLSYRDDSEVHGKGESTPSQTAWALMALMSADAVDSFSVARGVQFLLRWQ
MKDGSWEEISHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLRSRGKIRADELRHHIQGT
DLYRSKH
>A0A5B8DLQ0|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces albidoflavus|TrEMBL
MTATTNGPAAPSRPAPARTTATTTDTAAPDAAAVEAAAERARARAADHLLGLQSPEGWWK
GDLDTNVTMDAEDLLLRQFLGIRDEATTRSAALFIRGEQREDGTWATFYGGPPDLSTTVE
AYVALRLAGDSPDAPHMTRAAHWVRSQGGIAEARVFTRIWLALFGWWPWDRLPELPPELI
FLPPWAPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPADPAPRARFAPLA
SWNGAFQRLDRALHAYRKVAPRALRKAAMATAGRWIVERQENDGCWGGIQPPAVYSMIAL
HLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQSPVWDTCLATIALADAGVPADHP
QLVRAADWMLGEQIERPGDWSVRRPHLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHP
DTARMERAISLGVRWNLGMQSKNGAWGAFDVDNTSSLPNRLPFCDFGEVVDPPSADVTAH
VVEMLAAEGLAADPRTRRAVDWLLAEQEPSGAWFGRWGVNYLYGTGSAVPALIDAGLPTT
HPAVRRAVAWLESVQNDDGGWGEDLRSYREQGRMARGASTASQTGWALMALLAAGERESR
AARRGVTFLAETQHEDGSWDEPYYTGTGFPWDFSINYHLYRQVFPLTALGRYTRGAAPEG
A
>A0A7W9HBB3|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces caelestis|TrEMBL
MTATTDGSTGALPPRAAAASDTDTDTPAAAGVPEAAARAAQRATDFLLSRQDAEGWWKGD
LETNVTMDSEDLLLRQFLGIRDEKTTQAAALFIRGEQREDGTWATFYGGPGELSATIEAY
VALRLAGDEPGAPHMAKASAWIREQGGIAAARVFTRIWLALFGWWKWEDLPELPPELIYF
PKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPAHPNPAKPLAPAFSW
DGAFQRMDKGLHALRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSIIALHL
LGYDLQHPVMREGLASLDRFAVWREDGARMIEACQSPVWDTCLAAIALVDAGLPADHPQL
VKAADWMLGEEIVRPGDWSVQRPGLPPGGWAFEFHNDNYPDIDDTAEVILALRRIAHHDP
VRVDKAVRRGLRWTLGMQSKNGAWAAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVV
EMLAVEGLAHDPRTRRGIEWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALVAAGIPAAHP
AIRRAVTWLESVQNDDGGWGEDLRSYRYAKEWSGRGASTASQTAWALMALLAAGERDSKA
VERGIEWLAATQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYLHGEPFADR
HRGSGATGKPSAEAKGSGKIRMPLAEAKGAE
>A0A7C4BZY1|squalene-hopene cyclase|EC 5.4.99.17|Bryobacteraceae bacterium|TrEMBL
MEAASKALALSSDALMAARDQEGFWRGDLKADTTLESDYVLLQLWLHPPVDGEWKPPTWD
RIRKAARSILDRQLPDGGFNIYPKGPSEISACVKAYTALKLAGIDAHSPEMLKLRERILD
LGGVQAANSYVKINLSLFDLYPRDHVPTVPPELVLLPGDALYEMSSWTRAIVVPLSIVQA
VRPPKPLPRGFHLHEIFSDKPLHYDTGIKPSWRNFFLWVDRALKLWDKRAIKQIRGWALR
EAEHWILDRCRHSEGLGAIYPAMMYSIMALDALGYGPDHPDLLEAIRHFDSLLVETEDRF
YFQPCTSPVWDTAIAAFALGEAGTVPKEDLTPSADWLLTKEVRRKGDWSIKRPNLEPSGW
YFEFANEYYPDIDDTAMVLLALEHAKSSHPEKQERAERRAIQWILGMQSRNGGFAAFDVD
NDMEILNQVPFADHNAMLDPTCPDITGRVLEALVRRGVPPSDPAIQRAVDYLLGSQEAPG
CWYGRWGVDYIYGTFLAMRGLERSGERRAAEAIRRGAA
>A0A6P0XAI0|squalene-hopene cyclase|EC 5.4.99.17|Okeania sp. SIO2D1|TrEMBL
ILASQKYLLNLQKTEGYWWGELESNVTITAEIVLLHKIWKIDNKRPLDKAKNYLISQQRE
HGGWELFYGDGGDLSTSIEAYMALRLLGVAKTDPIMLKAQDFIIKKGGISCSRIFTKLHL
ALIGCYNWQGIPSIPPGIMLLPEDFPFTIYEMSSWARSSTVPLLIVFDKKPIFSVNPTIN
LDELYAEGINNASFELPRQYDLTDLFLGLDTAFKFLENLNLMPLREEGLKAAEKWILERQ
EVTGDWGGIIPAMLNSMLALRCLEYDVADPVVVRGLEAIDRFGIKTEDSYWVQPCVSPVW
DTAWVIRSLVDSGIPPSHPAVVKAGEWLLEQQILDYGDWAVKNKFGKPGGWAFEFINRFY
PDIDDTAVVVMALDAVELPDKELKSQAIARAMEWVASMQCEPGGWAAFDVDNDQDWLNGI
PYGDLKAMIDPNTADVTARVLEMVGCCGLSMDSWRVKRAIAYLEREQEEEGCWFGRWGVN
YIYGTSGVISALAVVAQESHGGFIERGATWLVGCQNSDGGWGESCRSYNDPSLKGKGKST
ASQTAWALIGLLAAGEATGNFAREAIDRGVDFLVSTQNDDGSWLESEFTGTGFPCHFYIK
YHFYPQYFPLMALGRYKNLLGG
>A0A6I0BV14|squalene-hopene cyclase|EC 5.4.99.17|Priestia endophytica|TrEMBL
MWTKQAKQHTTHLIKELRELQQENGSWHFPFETGVMSDAYMILTLRALGVEEEPLIAKLS
KRILSLQHKDGTWRHYEDEPKGNLSATIQAYTALLVAGASSKEETHMKRAERFIQQNGGV
KKAHFLTKWMLCANGLYPWPRFFYVPMTIMNIPTSFPLNFFSLSTYARIHFVPMMIAANK
KFSIPSNHSIYSLYEREETEEEWNVEDERFIIKDLLFYLKRLRNLPSYMHQAGYKKAESY
MISRIEDDGTLYSYATATFFMIYGLLALGYEKTSPLIINAVNGLKKLVTTIDGMDHLENS
TSTVWDTALLSYSLQESGVSYKDPMIKKASFYLLNKQHKKVADWAVHNPHIAPGGWGFSH
NNTINPDLDDTSAALRAITAPSVHDNRYLSSWNRGVDWLLSMQNRDGGWAAFEKNVDFQL
LTHIPLKNAEDAIIDPSTADLTGRVLQFLGKFAGLTEKHPAVKRAVKWLCDQQEKDGSWY
GRWGVCYIYGTWAALTGMRAVGVPLDDPHIQKGVLFLKKHQRQDGGWGESCRSSEVKKYV
PLLFSTPSQTSWALDALLTCLPKEHVTIKNGVKFLLTPHIHKAKTYPTGIGLPEQFYIRY
HSYNYIFPLLALSHYCQA
>A0A0H5DAM2|squalene-hopene cyclase|EC 5.4.99.17|Alloactinosynnema sp. L-07|TrEMBL
MDRLSSSTVATALGALSLHRADPAGHRDRIAAAVGWLNANQRADGGWSMADAEPPSSPGM
SAFAIAALHEIDPDASRGALERGWAFLDANDAENVIPGLRGQAPKTWPAALPTIWGLVGL
RDPREQPDQPVEAVLLPSRLRNKVSIALPVILALGVMQARTLPRGPLRRLTSRIARPKAL
DWLREVSGANGGIEECPMIAGFVYLGLHAAGVGRDLQLASSRYLLSTQRTDGSWAIDRDL
EISVTAYAVMALTEFSDVAAEPQLHRTRDWLLDAQWNRPFTPLGLPAGGWAWANPSGWPE
TEDTAVVLGVLADLGVPRGHPAVELGIRWLLRMQNRDGSWSEWVRNSAIMNDRPCAGVTA
HAILALHRFGVSRAPGSAIARGLSYLDNHRQADGSIASVWFRDSTHGTSRLLEAFTATRH
GASPAARAAHRRLVAEQADDGGWPRHHELPPEGTTAEETAWALFALLHAGHDPADPAVLR
AVDWLVDRQDDLGTWRPSNVGLYFDDLCYTDDLIAHTFALRALGRFLRVTDRSGAR
>A0A3E0LJ43|squalene-hopene cyclase|EC 5.4.99.17|Microcystis wesenbergii TW10|TrEMBL
MQIQDKITEIAAKTAKAIELSQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDK
NRPLDKAATYLRQQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPANDPALEKAREFI
LAKGGISKTRIFTKMHLALIGCYDWLGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPL
LIVFDKKPVYKMGFNLDELYTEGVNNVKYELPKNNDWADVFLWLDGLFKWAEKTDLVPFR
QESLKAAEKWVIERQEDPGDWGGIIPAMLNSLLALKALGYDVYDPIVARGLKAVDNFAIQ
TDNTYCVQPCVSPVWDTAWVIRALIESGLNPAHPAMIKAGQWLIDQQILDYGDWAIKNKI
GTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPDENIKKGVMKRAVNWMATMQCKAGGW
GAFDIDNDQNWLNSLPYSDLKAMIDPNTADVTARVLEMLGTCDVNMEENRVKKALDYLEK
EQEADGSWFGRWGVNYIYGTSGALSAFAFLEPNKYRHQLQKGANWLSSCQNVDGGWGETC
FSYNNPKFKGQGNSTASQTAWALIGLLAVGKVTGNYQREVIEKGVNYLLVTQKENGTWDE
DYFTGTGFPCHFYLKYHFYQQYFPLLALGRYRALI
>A0A5A8ES29|squalene-hopene cyclase|EC 5.4.99.17|Cupriavidus gilardii|TrEMBL
MSGPAFGLVAIIARPPNTDRGFARAGRGPAPPAASRCHCVTRSDVAEIQIALTGSPPAVD
PVDTQDRPDTVVSLAPSLPSFTAPTDLAGSRLDAAIAHAVDALIARQRPDGHWVFELEAD
TTIPSEYVLLVHYLGEPADPAREARIARYLLRRQNDDGGWPLFHGGASDISASVKAYFAL
KMIGEPVDAPAMRRARECILALGGAEASNVFTRTLLALYGVMPWRAVPLMPVEIMLLPLW
FPFHLSKISYWARTVIVPLLVLNTLRPCARNPRRVGIDELFRRPSQAARMPGRAPHQSRF
WYAVFRGVDVALRVLEPLSPRALRQRAMQQAERFVRERLNGDDGLGAIFPAMVNAVMMFD
ALGVPRDEPAVAQARAALDRLLVEHGGDGDETYCQPCFSPVWDTSLTCHAMLEAGGERAL
AAARRALDWLLPLQVLDVRGDWTVRRPHLRPGGWAFQYANPHYPDVDDTAVVAMALDRAA
RGDARWGGRVAPALARAREWIEGMQSSDGGWGAFEPENTHSHLNSIPFADHGALLDPPTA
DVSARCLSMLAQLGELPANSRAAAQALRYLLDEQEANGSWYGRWGTNYLYGTWSALCALQ
AAGLGPDAAPVRRAAQWLLSVQNEDGGWGEDGSSYRLDYRGHESAPSTPSQTAWALLGLM
AAGCREQPAVARGIDYLLREQRADGLWDEQHFTAVGFPRVFYLRYHGYARYFPLWALARY
RNLGNPGDLGNPGDPGDPRNRGGLGNQADAAVPNDAAGRMPWGM
>A0A7K2B1L7|squalene-hopene cyclase|EC 5.4.99.17|Acidimicrobiia bacterium|TrEMBL
MAALPWLTSGPGAGDLERDAADALARSAGALLGLQDPAGWWKGDLETNVAIEAEDLLLRT
FLGICDDETLALTANWIRSKQCADGGWSNRYGGPSELSLAVEAYTALRLAGDSPDAEHMR
LAAEFVRDMGGLECSRVFTRIWLSLFGQWSWRDLPAIPPELILLPRWLPLNIYDFACWAR
QTIVPLSIVSTYRPQVELGFTLDELRTGAVPPERVPRSIRTPAGCFQRLDRMLHKFHDLA
PWRLRETSMKLAEQWIIRRQESDGCWGGIQPPWIYSIIALHLRGYSLDHPVLAKALACFD
SYEVRQGDMRWMECCQSPVWDTALAVVALGDAGLRRDDPAMVAAADWLLDEEVRVRGDWA
ARRPQLAPGGWAFEFQNDNYPDLDDTAEVVLALGHAQASDPERANAAIARAVAWAEGMQS
SDGGYAAFDADNVRRLCEQLPFCDFGEVIDPPSSDVTAHVVEMLCWVRARTDIPVDPRRL
RRAVDWLWLDQEPDGSWFGRWGVNHLYGLGAVLPALRAVGVPPSDRRIRRAVRWLHATQG
PEGGWGEDLRSYESDSWRGRGDSTASQTAWALLALMAADEFGEPTRRGVDWLARTCRPDG
TWEEPQYTGTGFQGYFYINYHLYRQVFPTMALGRFLRATAGEESLR
>A0A7X8CFF1|squalene-hopene cyclase|EC 5.4.99.17|Deltaproteobacteria bacterium|TrEMBL
MNPVTSKKESSSDYLERAFEGAFSSSDFSSGCRLSAFFQIEKGGGISGFNEAASLRLDSK
AYWKQQVKKAVESSSKFFLETQNPEGYWWAELESNVTITAEYIMLLHLLEISEPEKERSM
VKYLLHEQTSNGSWGLCYGDGGDISTTIEAYFALKLAGEDPDSEPLRRARGFILSKGGIE
SARVFTKIWLALFSQYDWDNVPSMPVELVLLPSHFYFSIYEFSSWARGTVVPLSIVLAIR
PRYKLPDSKAVPELYVKKAGSGSKRFPSMTHKLFYLFDRVAKAFERHPIPSLRNRAVQAA
ETWILEHQEETGDWGGIQPPMVYSILALHYMGYTLDHPVIEKGLEALEGFCLEDEHGLRM
QSCISPVWDTALTGLALVEAGISPEHPALVKATQWLLDKQIKKGGDWQVKNCCPPGGWAF
EFVNNHYPDVDDSAVVLTTLHRMGTNQCGGLECGKSMGMEWCLSMQSSCGGWAAFDRDNT
MTILNRIPFADTEAMVDYPTADVSGRVLETMGYYGYDRSDRRAKRGIKFIKDLQEPDGAW
WGRWGVNYIYGTWSVLRGLISIGEDPKAPYIQAAVRWLKEHQNPDGGWGETCESYRYPQL
RGKGASTPSQTAWALMGLLACGEEHSPEVRKGVQYLVETQKADGTWDEKYFTGTGFPNHF
YIRYRNYCNCFPLMALGQYRRKLQEE
>A1AN91|squalene-hopene cyclase|EC 5.4.99.17|Pelobacter propionicus (strain DSM 2379 / NBRC 103807 / OttBd1)|TrEMBL
MNPAKYKISSSLTSLNAEPVEQAPLPAKRTGSKVHRLPPSIWKKMVAEAKSPLDKGIERT
RDFFLREQLPDGYWWAELESNVTISAEYVMLFHFLGMVDRERERKLANYILAKQTSEGFW
SLWHNGPGDLSTTIEAYFALKLAGYSADHPAMAKARAFVLANGGIIKARVFTKIFLALFG
EFAWFGVPSMPIELMLLPDWAYFNMYEFSSWSRATIIPLSVVMSERPVRKLPPRAQVQEL
FVRPPRPTDYTITREDGLFTWKNFFIGADHLIKVYESSPIRPFKKRAVALAENWILEHQE
QSGDWGGIQPAMLNSILALHCLGYANDHPAVAKGLDALANFCIEDDDCIVLQSCVSPVWD
TALALVALQEADVPADHPALVKAAQWLLNLEVRRKGDWQVKCPELEPGGWAFEFLNDWYP
DVDDSGFVMLSIKNIKVRDRKHREEAIKRGIAWCLGMQSENGGWGAFDRNNTKYLLNKIP
FADLEALIDPPTADLTGRMLELMGNFDYPKSHPAAERALAFLKKEQESEGPWWGRWGVNY
LYGTWSVLCGLEAIGEDMNQPYIRKAVNWIKSRQNNDGGWGEVCESYFDRSLMGSGPSTA
SQTGWALLALMAAGEANSRAAAQGVKYLLETQNEDGTWDEDAFTGTGFPKFFMIKYHIYR
NCFPLTALGRYRRLTAAKG
>T2AYY4|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAMHAVLEANSVPDKIIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDYYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSRNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAVARAIGYLKRGQEVNGSWFGSWG
>T2AXR1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGPAMHAVLEANSVPDKTIMEKAANWLVERQILDVIGDWGANAHGVRPGGWAFQY
WNDCYPDVDDTAVVVMALHRADSARYSEAIARGAEWIIGMQSGNGGWGAFDVDNEHHFLQ
HIPFADHGALLDPPTADVSARCLSMMAQLGYGPDNQAIARAIGYLKRGQEVNGS
>T2AZS7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLATHAMLEANLTSGPRTLDSDNISKACKWLANPQIKDCRGDWAIWRPNLRPGG
WAFQFRNDYYPDVDDTAVVAMALHRTGNKSYEPILQRAAEWIIGMQSKNGGWAAFDAVNE
YHFLENMPFADHGALLDPPTADVSARCVSFLTQMGYDRSHDAIKRGIEYIKKRQEKDGSW
YGRWG
>T2B0B3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAICSNALLDSGLPTDHPALVRAGKWIVSKQVTKRGDWQVKNPKAEPGGWAFEFY
NELYPDTDDTAEILLFLNRVEIPDNRWKLSECQRAMGWLLSMQSKSGGWGAFDVDNDKDV
LNEVPFADHKALLDPPTVDVSSRILWMLGKWGFNKQHPQVKRAIKFVKERQEIDGCWFGS
WG
>T2B0B6|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPELSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTNNKSYSEPIQRAANWVAGMQSRGGGFSSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAITLLSLADKKIYEKNIKDGINYIKSEQEEDG
>T2AXS3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTALVSQALIETEYKQHVSTEIETALNWLKEQQLSDEPGDWRIQKPGLSGGGWAFQ
YSNYYYPDLDDTSMVAWAMHRTKNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTADVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWFGSW
G
>T2AZH3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAALALQEADPKGTRQSREKAYNWLKTKQLDKQPGDWQIRQPHLEGGGWAFQF
ENPHYPDVDDTAVVAFAMANADLPNLNESINRATRWTAGMQSKNGGFGAFDCDNTDYYLN
HIPFADHGALLDPPTADVSARCAMLLGHQIKNHPEYQTTLDDTIAYLRSEQETDGSWYGR
WG
>T2AZF0|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGFNGLSLLESGLTLKDSSIQKACKWLEKKQILEIKGDWIVNNKNLLPGGWAFQY
ENDFYPDVDDTAVIVMFLDRAGYQNKKRLEIACNWIIGMQSKNGGWGAFDKDNTYHYLNN
IPVADHGALLDPPTADVSARCISMLSQINKKNYKKIIQKGVKFLKNEQENDGSWYGRWG
>T2B052|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAAHAVLETLGGNTLLLNKSCDWLSKLQIKEHTGDWGWRRKGLRPGGWAFQYN
NKFYPDVDDTAVVGMALHRQNPEKYADTISRAEEWIIGMQSSNGGWAAFDADNEYYLLEN
LPFADHRALLDPPTADVTARCISFLTQIGTSNNHPISRGLVFLKRNQEEDGSWYGRWG
>T2AYF5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
LALLESGIDPEDPMVQSSARWLIDKQIYAAADWQVRTKGTRPGGWSFEFDNLIYPDIDDA
SIVVMALDQVRLPEAEEARRADSIQRGVEWMAGMQSKNGGWAAFDKDNNKKYMTKIPFSD
FGETLDPPSVDVTAHLLEMYGRLGYTKEDRAVGRGFAYVISEQEEDGSWYGRWG
>T2B024|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTPWAIMALLKSGLPNNHPSLVKAGEWMLEKEVKTFGDWSLKNPVREPSGWYFQHA
NEFYPDNDDAAVVMMSLQLLDLPDKNRKSQAILRGFKWLMGMQCKDGGWGSFDKNNNKKI
LNNIPFADWNALLDPSTSDLTARVLDLMGKLGYDLSFRPAEKAIKFLKKEQEKNGSWYGR
WG
>T2B067|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAALALQEADPKGTRQSREKAYNWLKTKQLDKQPGDWQIRQPHLEGGGWAFQF
ENPHYPDVDDTAVVAFAMANADLPNLNESINRATRWTAGMQSKNGGFGAFDCDNTDYYLN
HIPFADHGALLDPPTADVSARCAMLLGHQIKNHPEYQTTLDDTIAYLRSEQETDGSW
>T2AZ21|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGFNGLSLLESGLTLKDSSIQKACKWLEKKQILEIKGDWIVNNKNLLPGGWASQY
ENDFYPDVDDTAVIVMFLDRAGYQNKKRLEIACNWIIGMQSKNGGWGAFDKDNTYHYLNN
IPFADHGALLDPPTADVSARCISMLSQINKKNYKKIIQKGVKFLKNEQENDGSWYGSWG
>T2B091|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLSGISLLESGLTLKDNAIQKACKWLEKKQILKIKGDWIANNKNLLPGGWAFQY
ENDFYPDVDDTAVVAMFLDRAGYQNKRRLERACNWVVEMQSKNGGWGAFDKDNTYYYLNN
IPFADHGALLDPPTADVSARCVSMLSQINKKSYKNAIQKGVSFLKNEQEEDGSWYGRWG
>T2AZG1|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
VWDTGIACNALMDAGLPKDHPALIKATEFFFRKQVVKRGDWQVKNPNAESGGWAFEFYNE
LYPDNDDTAEILMAIHSIEFPDLRYKLKESQRALSWLLSMQSKNGGWGAFDQDNDQELFN
AIPFADHNAMLDPPTVDVTSRIIWLLGILGYSREHPQVKKAIVYIISDQENDGSWYGRWG
>T2AYA5|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPMWDTAIVSIALRESGISEDDPQIRESCDWLIDREIRFRGDWYHKNPVEVEPSGWVFEF
NNKWNPDVDDTAMVLMALRQTPTDNQQRRDESFKRGMEWMKAFQCRDGGWAAFDKDCTKS
ILEKVPFADHNAMLDPECADITARILELLGYEGYPVDDPQVKRGLAYLRSQQETDGSWYG
RWG
>D8PBL8|squalene-hopene cyclase|EC 5.4.99.17|Nitrospira defluvii|TrEMBL
MQLLKNLFNRLSDSLLVSVPSRIRAARDFASAPVLRLVSNKPDAPVGDSAAKRAPAHSTG
QVEALEEALRKSQAWFLARQDASEGYWVAELEADTTLTSEYLMLRRFLDCIDPERERKAV
RYLKSAQLPDGGWPIYHGGPAEISASVKAYFALKLSGVSADEPFMVNARTCILDKGGVVA
ANVFTKIALALFGQYDWRGVPSMPPEIMLLPKRFYFSIYAISYWSRAVLIPLLIIFAKRP
MCHVPSEQGIDELYTQPPAEIDYGTVPPFRKDRTWFTARNFFINLDALLKIYDRSPVEWV
RQKALKCAENWMLDHMKGSGGLGAIYPAMANSVMALHCLGYKNDDPLMVKAMREIEELEI
HDTVQDNGQCVDAMHLQPCHSPIWDTALLINALIEAGMPQDHPALQKASTWLLFKQTKTV
GDWIISSPGAEPGGWYFQFENELFPDVDDSAVVLMALAKVHLSDEAQQRLAIRRGCRWVT
AMQGSDGGWGAYDVDNNRIVFNYIPFADHRALLDPSTADLAGRCLEMLATLGYDWTHPAV
ASALTFVKNDQEQDGSWYGRWGVNYIYGTWSVLSGLRAIGEDLSSPYIRRAVSWVESKQN
PDGGWGESCLSYGDVSQSGRGDSTPSQTAWALLALMAGGVTDSFSLARGIHYLIRNQRKD
GSWEEVRHTGTGFPRVFYLRYHWYCQYFPLWALAMYRNLKTRGTTRADELRLQAYQSGQF
RSPR
>T2AZK3|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAAHAVLETHGGNTHLLNKSCDWLSKLQIKEHTGDWGWRRKGLRPGGWAFQYN
NKFYPDVDDTAVVGMALHRQDPEKYADTISRAEEWIIGMQSSNGGWAAFDADNEYYILEN
LPFADHRALLDPPTADVTARCISFLTQIGTSNNHPISRGLEFLKRNQEEDGSWFGRWG
>T2AYC7|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLSGISLLESGLTLKDIAIKKACTWLEKKQILGMKGDWVANNKNLLPGGWAFQY
ENDFYPDVDDTAVVAMFLDRAGYQNKKRLERACNWIIGMQSKNGGWGSFDKDNTYHYLNN
IPFADHGALLDPPTADVSARCISMLSQINKKNYKNVIQKGVEFLKNEQEEDGSWYGSWG
>T2AZX8|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTSLATHAMLEANLSSGPRILENDSTSKACKWLEKLQIKDCAGDWAVWRPNLRPGG
WAFQYHNDYYPDIDDTAVVAMALHRTGNKTYEPALLRAAEWIIGMQSKNGGWAAFDADNE
YHLLENMPFADHGALLDPPSVDVSARCISFLTQLGYDQTNGTIKRGIEYLKKNQEEDGSW
YGRWG
>T2B054|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTGLAVHAMLEAGEPKNGARLNKAMRWMADRQVCDVSGDWATHRPGLRFGGWAFQY
ANDHYPDVDDSAVVAMALDRASDPKVKQGLPRAVEWIVGMQSKNGGWGSFDAENSHYHLN
HIPFADHGALLDPPTEDVTARCVGMLAQIGDEAGNDAIERGLSYLRETQQPDGSWYGKWG
>T2B064|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPIWDTALVSQALIETEYKQHVSTEIETAPNWLKEQQLSDEPGDWRIQKPGLSGGGWAFQ
YSNYYYPDLDDTSMVAWAMYRTKNKSYSEPIQRAANWVAGMQSRGGGFGSFDINNTHFYL
NEIPSADHGALLDPPTVDVTGRAIALLSLADKKIYEKNINDGVNYIKSEQEEDGSWYGRW
G
>T2AZ45|squalene-hopene cyclase|EC 5.4.99.17|uncultured bacterium|TrEMBL
SPVWDTAIVSIALRESGTSEDDPRIRESCDWLIDREIRFRGDWYHKNPVEVEPSGWVFEF
NNKWNPDVDDTAMVLMALRQTPTDNQQRRDESFKRGMEWMKAFQCRDGGWAAFDKDCTES
ILEKVPFADHNAMLDPECADITARILELLGYEGYPVDDPQVKRGLAYLRSQQETDGSWYG
RWG
>A0A850IP57|squalene-hopene cyclase|EC 5.4.99.17|Bradyrhizobium sp. 323S2|TrEMBL
MDSVNATSREAQESRALESRILESGVLESSIASATQGVLGFQQSDGHWVFELEADCTIPA
EYVLLRHYLAEPVDAVLEAKIGNYLRRVQGAHGGWPLVHDGEFDMSASVKSYFALKMIGD
SVDAPHMVRAREAIHARGGAINSNVFTRFLLAMFGVVTWRAVPVLPIEIVLLPFWSPFHI
NKISYWARTTMVPLMVLAALKPLAKNPKGVGIDELFLQDPRSIGMTAKAPHQSMAWFVLF
RALDGILRVIEPMFPKSLRQRAIDAALAFTEERLNGEDGMGAIYPPMANIVMMYDALGKD
ENYPPRAVTRRGIDKLLVIKGDEAYCQPCVSPVWDTTLTAHALLEAGGDIAEPAAKQGLD
WLIPKQELEVKGDWAVKRPDVRPGGWAFQYNNAYYPDLDDTAVVVMSMDRMRREHGATGY
DAAIDRGREWIEGMQSDDGGWAAFDVNNLEYYLNNIPFSDHGALLDPPTEDVTARCISML
AQLGETEKSSKHVADGVAYLRKTQHPEGSWYGRWGMNFIYGTWSVLCALNMAGVRHDDPM
IRKAADWLASIQNKDGGWGEDAVSYRLDYKGWEAAPSTASQTAWALLALMAAGEVDHPAV
ARGVEYLIATQNKKGLWDEQRYTATGFPRVFYLRYHGYPKFFPLWALARYRNLRNTNSRV
VGVGM
>B1PT66|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces peucetius subsp. caesius ATCC 27952|TrEMBL
MTATTDGSSGPLRGGAATAGETTSTSAARTTEPGTDLREAAARAAERAVEHLLARQDAEG
WWKGDLETNVTMDAEDLLLRQFLGIQDPATVGASARFIRGQQRDDGTWATFYGGPGELST
TVEAYVALRLAGDRPDDPHMQRAASWVRSRGGIAASRVFTRIWLALFGWWKWEDLPELPP
ELIFLPKWFPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFALDELHTDPALPNPGKRLA
PAASWDGFFQRADKALHAYHKVAPRRLRRAAMNAAARWIIERQENDGCWGGIQPPAVYSV
IALHLLGYDLEHPVMRAGLESLDRFAVHHEEEGLPVRMIEACQSPVWDTCLATIALADAG
LPADHPALVKAADWMLSEQIVRPGDWSVRRPGLGPGGWAFEFHNDNYPDIDDTAEVVLAL
RRVKHPDPERVDAAVARGTRWNLGMQSRDGAWGAFDADNTSPFPNRLPFCDFGEVIDPPS
ADVTAHVVEILAHEGMAHDPRTRRGVRWLLAHQEANGAWFGRWGVNYVYGTGAVVPALTA
AGLPGSHPAIRRAVAWLESVQNEDGGWGEDLRSYREEKSIGRGVSTASQTGWALLALLAA
GERESKAVERGVAHLAQTQAPDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVH
GEKLPGRAGAREGR
>P73914|squalene-hopene cyclase|EC 5.4.99.17|Synechocystis sp. (strain PCC 6803 / Kazusa)|TrEMBL
MVIAASPSVPCPSTEQVRQAIAASRDFLLSEQYADGYWWSELESNVTITAEVVILHKIWG
TAAQRPLEKAKNYLLQQQRDHGGWELYYGDGGELSTSVEAYTALRILGVPATDPALVKAK
NFIVGRGGISKSRIFTKMHLALIGCYDWRGTPSIPPWVMLLPNNFFFNIYEMSSWARSST
VPLMIVCDQKPVYDIAQGLRVDELYAEGMENVQYKLPESGTIWDIFIGLDSLFKLQEQAK
VVPFREQGLALAEKWILERQEVSGDWGGIIPAMLNSLLALKVLGYDVNDLYVQRGLAAID
NFAVETEDSYAIQACVSPVWDTAWVVRALAEADLGKDHPALVKAGQWLLDKQILTYGDWQ
IKNPHGEPGAWAFEFDNNFYPDIDDTCVVMMALQGITLPDEERKQGAINKALQWIATMQC
KTGGWAAFDIDNDQDWLNQLPYGDLKAMIDPSTADITARVVEMLGACGLTMDSPRVERGL
TYLLQEQEQDGSWFGRWGVNYLYGTSGALSALAIYDAQRFAPQIKTAIAWLLSCQNADGG
WGETCESYKNKQLKGQGNSTASQTAWALIGLLDALKYLPSLGQDAKLTTAIEGGVAFLVQ
GQTPKGTWEEAEYTGTGFPCHFYIRYHYYRQYFPLIALARYSHLQAS
>Q9X7V9|squalene-hopene cyclase|EC 5.4.99.17|Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)|TrEMBL
MTATTDGSTGASLRPLAASASDTDITIPAAAAGVPEAAARATRRATDFLLAKQDAEGWWK
GDLETNVTMDAEDLLLRQFLGIQDEETTRAAALFIRGEQREDGTWATFYGGPGELSTTIE
AYVALRLAGDSPEAPHMARAAEWIRSRGGIASARVFTRIWLALFGWWKWDDLPELPPELI
YFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPARPNPPRPLAPVA
SWDGAFQRIDKALHAYRKVAPRRLRRAAMNSAARWIIERQENDGCWGGIQPPAVYSVIAL
YLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGVPEDHP
QLVKASDWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHH
DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSAFPNRLPFCDFGEVIDPPSADVTAH
VVEMLAVEGLAHDPRTRRGIQWLLDAQETDGSWFGRWGVNYVYGTGSVIPALTAAGLPTS
HPAIRRAVRWLESVQNEDGGWGEDLRSYRYVREWSGRGASTASQTGWALMALLAAGERDS
KAVERGVAWLAATQREDGSWDEPYFTGTGFPWDFSINYNLYRQVFPLTALGRYVHGEPFA
KKPRAADAPAEAAPAEVKGS