>P22304|iduronate-2-sulfatase|EC 3.1.6.13|Homo sapiens|Swiss-Prot
MPPPRTGRGLLWLGLVLSSVCVALGSETQANSTTDALNVLLIIVDDLRPSLGCYGDKLVR
SPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRPDTTRLYDFNSYWRVHAGNFSTIP
QYFKENGYVTMSVGKVFHPGISSNHTDDSPYSWSFPPYHPSSEKYENTKTCRGPDGELHA
NLLCPVDVLDVPEGTLPDKQSTEQAIQLLEKMKTSASPFFLAVGYHKPHIPFRYPKEFQK
LYPLENITLAPDPEVPDGLPPVAYNPWMDIRQREDVQALNISVPYGPIPVDFQRKIRQSY
FASVSYLDTQVGRLLSALDDLQLANSTIIAFTSDHGWALGEHGEWAKYSNFDVATHVPLI
FYVPGRTASLPEAGEKLFPYLDPFDSASQLMEPGRQSMDLVELVSLFPTLAGLAGLQVPP
RCPVPSFHVELCREGKNLLKHFRFRDLEEDPYLPGNPRELIAYSQYPRPSDIPQWNSDKP
SLKDIKIMGYSIRTIDYRYTVWVGFNPDEFLANFSDIHAGELYFVDSDPLQDHNMYNDSQ
GGDLFQLLMP
>Q08890|iduronate-2-sulfatase|EC 3.1.6.13|Mus musculus|Swiss-Prot
MSPPPPPPIWRQLSFSLLLGSFCIALESAAQGNSATDALNILLIIVDDLRPSLGCYGDKL
VRSPNIDQLASHSVLFQNAFAQQAVCAPSRVSFLTGRRPDTTRLYDFNSYWRVHSGNFST
IPQYFKENGYVTMSVGKVFHPGISSNHSDDYPYSWSFPPYHPSSEKYENTKTCKGQDGKL
HANLLCPVDVADVPEGTLPDKQSTEEAIRLLEKMKTSASPFFLAVGYHKPHIPFRYPKEF
QKLYPLENITLAPDPHVPDSLPPVAYNPWMDIREREDVQALNISVPYGPIPEDFQRKIRQ
SYFASVSYLDTQVGHVLSALDDLRLAHNTIIAFTSDHGWALGEHGEWAKYSNFDVATRVP
LMLYVPGRTAPLPAAGQKLFPYRDPFDPASDWMDAGRHTEDLVELVSLFPTLAGLAGLPV
PPRCPIPSFHVELCREGQNLQKHLQLHDLEEEPDLFGNPRELIAYSQYPRPADFPQWNSD
KPSLNDIKVMGYSIRTVDYRYTVWVGFDPSEFLANFSDIHAGELYFVDSDPLQDHNVYND
SQHGGLLHSLRP
>A0A8B6G6P1|iduronate-2-sulfatase|EC 3.1.6.13|Mytilus galloprovincialis|TrEMBL
MNIWHGLLFLLVLVTISEGKLNVLLIVADDLRPSLGCYGYEPLITPNIDLLASQSVVFNR
TYAQQAICGPSRASFLTSRRPNTTHVYDQHTYWRKRGGNFTTLPQHFKNNGYVTFSVGKI
FHPGAASGKTDDYPYSWSVPPYHPSTQQYKMAKVCPGPDGKLYMNIVCPVDVIAMPEKTL
PDLQSTQHALQIMQNVSRFPEQPFFLAVGYHKPHIPLKYPREYLNLYPLDKIHLAPDPLM
SNDIRTY
>A0A7Y9SXJ7|iduronate-2-sulfatase|EC 3.1.6.13|Sphingopyxis sp. JAI108|TrEMBL
MRRTAHWSRRAMLALLITATSACSQTPAPRAALTPAPAPATAQRPNVLLILVDDLKPALG
TYGDRTAITPNMDRLAQRGLKFNLAYANEAVCGPSRINLMTGARSTSSGIYNFGMNLRDY
MPGAVTLPQHFMRAGYHTESMGKVYHIGHGTVGDTAGWSVPHHKEKVIEYVDPASTGGKP
TQEEALFEEIPVPEGNPFAYARTLARGAAWEMPDVADDAYADGRTAKRAEERLKALKQGN
QPFFLAVGFARPHLPFSVPKRYWDMYDPAKLPMPDFEQLPAGAPAYTDKQGGEITAYREP
PEDVRGDKFPAELKRTLLHGYYAGVSYVDVQIGKVLKALEREGLADNTIVVLWGDHGYHL
GDHGIWTKHTNLEQATRIPLIFAGPGVVKGGSTDQLAETVDIYPTLAALAALPAPNGPQP
IDGISLAPVLHDPATRVRGYAYHAYPRPGRLGQAIRTDRYRLVRWTEEKTGARDYELYDL
VADPEETRNQADALPKVRAELDAILDTQPAARPINGKPRRN
>A0A7W5E2E5|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula rubra|TrEMBL
MNHDMQLKTFSKILLLTLILVPCSVNAGERPNVLFIAVDDLRPSIGCYGDPHAITPNLDR
LAASGVQFNRAYCQVAVCNPSRASLMTGLRPDKLGVWTLPIHFREAMPDAITMPQWFRKF
GYTAVSHGKIYHNPTPDPQSWSEPIRSLPSLPYVYPEGTRTRVKKVQDGLPKNDWRKNNL
RGPSTASPDFADDQVLDGARTKMAIEDLRRLGKQSEPFFLAMGFIRPHLAWVAPKKYWDM
HDPSELPVVSDQRITPNTPAYALHNNSELTHYVDLKDLPRPWDDRDVSAEKARHLMHAYY
ACVSYVDAQIGRLLDALEEEGLADNTIVVLWSDHGWKLGEYRGWGKMTNYEIDARVPLLI
AGPGVQEVGKQTDQLAELLDLFPTLCEMTGIEVPKFVDGKSLMPILKDVDASVHEGAVNQ
YYRNFGGNQYMGYSIRTNEYRLIEWRDFDSGHVTDRELYDHRTEHSETVNIVESADKGVV
DQLTDVLLQTHPRKGLVMRPLIHSDPHPEKLQSEMFFQNATDSVVQVYPITPAGRRGKVL
RLQPDGLRTVSAIVGTVYVAESVDGSIYEIHTATESGVTVVFRDGAISE
>M5RDG4|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula maiorica SM1|TrEMBL
MKYYVVFLVSCLSFPAFVANAAERPNVLFIAADDLRNDLRCLGNPEVLTPNIDALAERGR
LFTHAYCQQALCNPSRASLMSGLRPDTLEIWDLRTHFRDQMPNVVTLPQHFMKHGYFTQN
IGKIYHNWVHDLKGDPASWSVPAVMHFATHRSDQPIVDGKLPPNLAKDIKCECRDVPDDA
YFDGRIASLAIDALRERKTNDQPFFLAVGFWKPHSPFNPPKKYWDMYDRDALSPPQNPDW
PKNAPRIAWHNSQEIVGSKNPRPLSVDAVMEMRHGYLAAISYLDAQVGRVLDELDALKMR
DNTIVVFWSDHGFHLGEQTLWAKTSNFELDAAVPMIFSAPGMQHRGTKTDSLAELIDMAP
TLTGLAGLPPLDGVEGVSLVPILKDPTATVKQAAYTQHPRPAYYKDAPAVMGRSVRTARY
RYTEWRDWDTTKSLALNYMTTTSILWKPSTLPQPPRTRMPSKHASVCIAWDSSHPEANKQ
RGRILSVYQPLWPTL
>M5RNP0|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula maiorica SM1|TrEMBL
MPRLISSTLIVVWMISVLVVIDAKAEPQTRPNILFIGVDDLRPELGCYGSPIAVTPNMDA
LATSGLRFNRAYCQQAICGPSRVSLLTGTRPDTNGITHNYVKLRQRNPDILTLPQHFGNH
GYDTVYLGKIFHHGDLDPASWNRQPSKNRREVRNLKKPVGFALPENQKIQKETRKQMIAK
YGDVAKLGLAMGPAYESANVPDNTYGDGYHTDLAIATLKDLVADDNKPFFLALGFNKPHL
NWVAPKRYWDLYDREEIPMATQTEAPQDGAAVGLHPSFELRVRSGIPKIGEMDPDLSRTL
KHAYLACVSYVDAQVGRIIAALDESGVRDNTIIILWSDHGYHLGEMGMWCKATNYELATR
VPMMIWTPQMPSANRGKATDGLVELVDIYPTLCDLAGIEPPSHLEGTSFKPLIANPARAW
KTAAFSQFPSPALREWGSFPIRPAMRETYFGPLLNQVEHRIQTQMGSKWDRELFEHDLTG
YAMRTDRYRIVAWKDTKHPDTAPLFVELYDHQTDPAETKNVANEHPERVAELLSQLNAGW
TAAAPAAQEAK
>Q32KH3|iduronate-2-sulfatase|EC 3.1.6.13|Canis lupus familiaris|TrEMBL
MPPGGWCLLCFGLVLSSVCASAESAAPSNLTTAPLNVLLIIVDDLRPSLGCYGDKLVRSP
NIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRPDTTRLYDFNSYWRVHAGNFSTLPQY
FKENGYVTMSVGKVFHPGISSNYSDDSPYSWSIPPYHPSSEKYENTKTCRGPDGELHANL
LCPVDIADVPEGTLPDKQSTEQAIRLLEKTKTSTRPFFLAVGYHKPHIPFRYPKEFQKLY
PLENITLAPDPEVPAGLPPVAYNPWMDIRQREDVQALNLSVPYGPIPVDFQRKIRQSYFA
SISYLDTQVGHLLSALDDLQLANSTIIVFASDHGWALGEHGEWAKYSNFDITTRVPLMFY
VPGRTAPLPEAGEKLFPYIDPFSSVQELMEPGRQVTDLVELLSLSPTLAGLAGLHVPPRC
PVPSFHVELCREGQNLMKHFQVEDVEGDPHLRGNPRESIAYSQYPRPADSPQWNSDKPSL
KDIKVMGYSIRTIDYRYTVWVGFSPHEFLANFSDVHAGELYFVDSDPLQDHNMYNDSQGK
DLLRAFDAIFLANH
>A0A7W5H7F7|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula rubra|TrEMBL
MLHGTLMLAVLCLGWSSNGVSEDRRNVLLICVDDLRPELNCYGVDYIQSPNIDRLAGQGC
RFDRHYVQAPTCGASRYAMLTGQYGDAGNDALFKRAERIEKTPESVASSMPRWFRDRGYT
TVSIGKVSHHPGGRGGKDWDDDQVIEMPGDWDRHLMPTGPWQHPRGAMHGLANGEIRVEP
TEMDVFQSAPNESDRYPDDLVAETSLEQLNILASDAESKPFFLAVGFIRPHLPFGAPERD
MEPYRDAVLPLISNVAKPDGRTTWHRSGEFMRYHRWGKDPNQDSEFAIAVRKHYAACVTY
ADRNVGCVLDELDRLGLSESTIVVLWGDHGWHLGEHAIWGKHALFEDDLRSPLIIRAPGQ
VEEGISTNAVVESIDLFPTLCELAVSQSAPEATSGVSLGEILRNPSRDGHVAISYGKANT
IRTDAYRLVVHKDGFAELYDHRVDPLELSNVAKENPDVVSRLNAVLQERLVRKN
>A0A7W7YGI9|iduronate-2-sulfatase|EC 3.1.6.13|Prosthecobacter dejongeii|TrEMBL
MHLRQIFLFLFAAATAQAAKPNVLMICVDDLKPTLGCYGDVVAQTPNIDRLAKRGVLFEK
AYCNQAVCSPSRNALMTSLRPQTLGIYELMTNFRKAAPNAVTMTQHFMAQGYKAEGLGKI
LHVGHGNTDDAASWSVPSWKPKATTYVNEESTAVTREAKVGGDRGWATEKADTADETYAD
GLIAREAVKRLEAAAKKPDQPFFLAVGFIRPHLPFVSPKKYWDLYDPAKLPMPQVKDAPQ
GAPVYAGQPGGELRQYSDMPQTGPIDDATTRHLIHGYYAATSYMDAQLGLVLDALDDSGL
AQNTIIVFWGDHGWHLGDHGMWCKHTNYEQAARIPVIVAAPGAAAGVQSASFIETVDLYP
TLSDLAGLPAPQGLDGKSFAAVVKDPALKTRESVIHVYPRNNLLGRAIRTDRYRLVEWKK
PGSGEPADAFELYDYQEDPLETKNLASERPEVVKELTAILATHPEAKPQMKTAAAKGGAP
GKKKKKGKKN
>A9GML8|iduronate-2-sulfatase|EC 3.1.6.13|Sorangium cellulosum (strain So ce56)|TrEMBL
MKRSCIALAAFALSLSAPAIAQPVKVFVLAGQSNMVGYGVGRQLPVELQSQPDVWYDHYN
PDAREGGPYAAATSADWGPLEPKGEARRYGPEITFGRAIAAAYPEHRIAIVKMAQGGTNL
VDHWGRGLAPDPEVLYKSQLYHALLGKLDSATYEGDRALRYPEEVTRLDGALARLESEGH
PYEIAALVWMQGENEAGWSAAFSYGNTLRGFIAAIRADLGVPGLPVVLGRVSDNLYPANG
GPIAAGKEANIDAVRAAQVTVAEEDPRVAWVDTDDFTVRSPDDAYHFDSAAYQLLGERFA
EAYLALVREEGSSTASSSSSAGSAAAGGGGAAGGGAAGGGATAGSSGSAEAAGGAGSAGE
GGRGATAGSSGSTAATGSAGSAGEGGRGATAGSSGSTAATGSAEAAASSGGVAPGSAGGC
GCRTAAGQGPVAAAALALVALAGLRRRRSRGQG
>A0A8B6G6P3|iduronate-2-sulfatase|EC 3.1.6.13|Mytilus galloprovincialis|TrEMBL
MMNIWHGLLFLLVLVTISEGKLNVLLIVADDLRPSLGCYGYEPLITPNIDLLASQSVVFN
RTYAQQAICGPSRASFLTSRRPNTTHVYDQHTYWRKRGGNFTTLPQHFKNNGYVTFSVGK
IFHPGAASGKTDDYPYSWSVPPYHPSTQQYKMAKVCPGPDGKLYMNIVCPVDVIAMPEKT
LPDLQSTQHALQIMQNVSRFPEQPFFLAVGYHKPHIPLKYPREYLNLYPLDKIHLAPDPL
MSNDIRTY
>F0STJ7|iduronate-2-sulfatase|EC 3.1.6.13|Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / IAM 15109 / NBRC 103401 / IFAM 1448)|TrEMBL
MRSLISFVSVLILCLMSTSVEAASPNVLFIAVDDLRVELNCYGQKHVLSPNVDKLASEGT
LFERAYCQQTVCNPSRASLLTGLRPDTLRVWDLPTHFRMNWPDTVTLPQLFKNSGYHAQC
VGKIFHNWVQEDWKGDEASWSVPSVLHYANHYHDTPKIDGPLPPSSASGENGIECRDVPD
NAYYDGRVAEVAIDALDEISREEKPFFLAVGFWKPHTPFNAPKKYWDLYDRDQIPVPEHV
TPPTDVPEVALTSARYKGGPDTEYLRELHHGHLAAITYLDAQVGKVLAKLDETGLRNNTI
VVFWSDHGLHLGEHGLTRKTTAFELDAGVPMIIATPEHTAGQRTDALVELLDLYPTLADL
CGLDAPEDLEGVSLRPVLENPKADVKEVALTQTPRPNYLKGKLPELMGYSIRADRYRYTE
WRDFQSGEAQARELYDHQTDPLEMTNLAGHDGHADLIKKLGKQLDETLE
>Q7UZ92|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)|TrEMBL
MKRLHVSAILSFMIAASFPIECWSEQRPNVLFIAVDDLRPSIGCYGDPQAITPNIDRLAS
RSVQFNRAYCQVAVCNPSRASLMTGLRPDNLAVWTLPIHFREAMPEAVTIPQWFRRYGYT
AVSHGKIYHNPTPDPQSWSEPIRDLPRLPAFYPDGTREQMKKFDNELPDRDWRKNNLRGP
STAAPELADDQLLDGARTNMAIEDLRRLGKSDAPFFLAMGYIRPHLAWVAPKKYWDMHDP
SKLPVRTGEQIPKNSPPYAMHNNSEMTHYVDRMNLPKPWDDDTVPTEDARHLMHAYYACV
SYIDAQIGRLLSALKEEGLADNTIVVLWSDHGWKLGEHRGWGKMTNYEIDAHVPLLITGP
GVKCLGQQTDQLAELLDLFPTLCEMAGIDVPDFVDGSSLVPILNDVDAKVHDGAVNQYYR
RHEGRQYMGYSIRTSDYRLVEWRDFFSGEVAAKELYDHRNDDSENESIVDSTEPKVIDEL
TSLLLETHPRKSLVMTPTVHSKPQSDGASGTISFENHTEGLVKVHPITSAGRRGRSRRLQ
AGDKRTIRAKIGSVFVVESHDGTIHQIHSLSGPTETVSIQPE
>F0SMV3|iduronate-2-sulfatase|EC 3.1.6.13|Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / IAM 15109 / NBRC 103401 / IFAM 1448)|TrEMBL
MRLFAALFAAFLVSASIVSSVHAGDKATKPNILFIAIDDQNDWIGCLDGHPQIQTPNIDR
LAERGTVFLNAHCQSPLCNPSRTSLMTGKRPDNTGIYGLAPWFRDVPELQDLVTLPQYLR
QNGYQTASAGKIYHGGYGRKKKDDEFEILGPPAGVGVRPKKKLVQTPNPHPLVDWGVFPH
SDEDKGDWKVASWGVDQLEKKDLQEPFFLSVGFFLPHVPCYATQKWFDLYPDDDSVLPPI
VMNDRADTPRFSWYLHWKLPETRLQFLREADEWRNLVRSYLACTSFVDSQVGRVLDALEA
SGQADNTIIVLWSDHGWHLGEKEITGKNTLWDRSTRVPLIFAGPGVTAGQRCNRPAELLD
IYPTLVDLCGLPSLAQLDGHSLRPQLEDATAEREWPAITTHNANNHGLRTERWRYIEYAD
GSRELYDMEADLNEFTNLADKPEYAGVIANLRRQLPPTSKLPAPGSASRILTIDELGNVI
WEGKQIGPHDPIPEID
>E6XA82|iduronate-2-sulfatase|EC 3.1.6.13|Cellulophaga algicola (strain DSM 14237 / IC166 / ACAM 630)|TrEMBL
MTKYLKFFILLAIVSSCKENEVKKEEIKKQPNILFIAIDDLRPELGAYGSDIAISPNIDA
LAADGLLFNNAYCQEAICSPSRASVMTGARPETLRVIENYSYFRDLNPDIETLPQHLRAN
GYETVYTGKIFHPGYTDAALSWSRKADPNSISTKAPRTPGGFKLVENQELYKSNSAEMAK
KYGKESLKSGLGRGPAYEFVDLPDNEYEDGYNTDLAIATLKDMVKEGDKPFFLGLGFLKP
HLDWVAPKKYWDLYDDKDIKLAKETTGPKDGAEMGLHASFELRARANIPNAGEISDEQAI
QLKHAYLACVSYVDAQIGRMIDALDEAGIRDNTIIVLWSDHGWHLGDMGIWGKATNYEIA
TRVPLIVWSPEMAKENRGRKTDALVELVDMYPTLCELTGVSIPETVEGQSFAPLLKNPDL
EWKKAAFSQFPTPALREWAANPLSKGMRETYFGPLIEKVEERIIKQQGDTWDRDLFENRL
MGYSMRTKDYRFIVWKDYTKKDAEPIFVELFNHQTDPSETINIAKENPELVASLLVQLNK
GWQGNLSTSSN
>F4C4T1|iduronate-2-sulfatase|EC 3.1.6.13|Sphingobacterium sp. (strain 21)|TrEMBL
MSEIKKMTTVIITMLVLMVVPNLYAQILPRSTTAKKVNVLFIAVDDLRSQLGCYGDSVII
TPNIDRLAKNGIVFNNAYCQQAVCGPSRASLLTGRRPDVTKVWDLETHFRKALPNAVTLP
QYFKENGYQSLCVGKIYHDPAASQDSISWSAPEIMAVTGTVGHKYVLKKNSKAKGKAAAV
ECVNVPDSAYVDGMVCNAAIKVLREIKDKPFFLAVGFRRPHLPFTAPKKYWDYYKRDEIP
MPQQPAPPQNVPEIALHNSTELRGYTDVPDEGPIPPDKIRQLRHGYYASVTYTDMQIGRL
LDELNKQGLMDNTIIVLWSDHGYHLGELGLWCKSTNFESDTRIPLIISAPNIKNKGVYTD
GIVESVDLYPTLAQLAGLSIPDELDGLSMVPLMEAPERPWKKAAFSQFPRPWMYKNLPRV
MGYSVRTKDFRYTEWRNFKNGTIEFTELYRYQANGRLEEKNLAAMKQYDNIKITLKQLLD
DGWQKALPVKNR
>F0RBY5|iduronate-2-sulfatase|EC 3.1.6.13|Cellulophaga lytica (strain ATCC 23178 / DSM 7489 / JCM 8516 / NBRC 14961 / NCIMB 1423 / VKM B-1433 / Cy l20)|TrEMBL
MRYAQLILLLLFISSCQSQKETKKEIKKKPNILFIAVDDLRPELGTYGSEIAITPNIDAL
ASNGLQFNNAYCQEAICSPSRASLMTGARPESISVVENFTYFRDANPDIVTLPQQLWANG
YETVHTGKIYHGKYNDPKLSWSRKPVPHSQMSASKKPKFGFKLPENIKLHKENSAAMVAK
YGENALRNGLGKGPAYEFADYPDNEYEDGYNTDLAIATLKDMLNKNPNKPFFLGLGMKKP
HLDWQAPKKYWDMYNEDDIKLAQQKQGPKDGAAMGLHASFELRARADIPKKGDITDEQAI
KLKHAYLACVSYIDAQIGRMLKALEESGQRDNTIVILWSDHGWHLGDMGIWGKATNYEIA
TRVPLIINTPNMPKEIKGKKTDALVELVDMYPTLCDLVDVAVPNTVEGQSFKPLLSNPNL
DWKKAVFSQFPTPALREWAANPLSKGMKETSFGPLIEEVEEKIKKQQGDKWNRDLFENKL
MGYSMRTKEYRFIVWKDYKTKNAKPIFIELYNHLNDPNETINIAKENPEIVKKLLVQFNK
GWKGNLAQLN
>A0A812BMM2|iduronate-2-sulfatase|EC 3.1.6.13|Sepia pharaonis|TrEMBL
MTTPIPLAVLLICLKIDSSSSSSTAEKKNILFIVIDDLRPTLGCYGNNLMSTPNIDQLAS
KSIRFNNAYVQQAVCGPSRISFLTSRRPDTTHLYDFYSYWRLAAGNFTTLPQHFKENGYF
TASVGKVFHPGRASGFTDDYPYSWSIPAYHPPTEKYKMAKVCPGSDGKKHMNLICPVDVS
SMPKGTLPDIQSTKHAQKLIKEIVHNKTKPFFLAVGYHKPHIPFKYPKKFLDLYPLSKIK
LPADDTLPPGLPSVAWNPWDDIRRRDDVQKLNVSYPYGPIPEYFQKLIIQSYYAATSYMD
EQVGHLLSALDENGFAQNTIVSFVGDHGWSLGEHQEWSKFSNFEVAVRVPLMMYVPGLTS
KPGPAGTNFPFKDPLRNLKASTSFPFLGKKSAENAYLRWENSQLRTDANHFMRQHERKWR
MMQASQENEDLTIRFNHPNISSKKTTPVQTSGWISDALVELVDMFPTYSELAGLSVPGLC
PRNSSRVDFCTEGVSLVKILKETVELKKKKGKFGEHGKLAAFSQYPRPSDTPQHNSDLPK
LADIKIMGYSMRTTDCRYTEWVSFNHRQFAPNWDEVHARELYFHNSSDGLENHNQAYDKR
YHGLVLKLSEKLHQGWRAALPHKYNVN
>Q7UER3|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)|TrEMBL
MRSLLQLPFSSQQVDSPLVWILRSVIVTLVALASSINVFAEKPKNVLLICVDDLRPELGC
YGADYVSSPNIDSLAAKGIQFNRHFVQAPTCGASRFAMLTGCYGPSGNHALFQRAKKIAK
DPTSVTPSMPRWFRDHGYTSVSVGKVSHHPGGRGGADWNEEAEIEMPGAWDRHLMPTGPW
QHPRGAMHGLADGEIRKDASQMDVFQSAGGEAKYPDDLILETSLNELTTLAEDSANKPFF
LAVGFIRPHLPFGAPAEYMKPYRQSVLPMIEHPNKPFGQTTWHRSGEFMRYNRWGKDPNQ
DAEFADAVRRHYAACVSYADANVGEVLKQLDELGLRESTVVVVWGDHGWHLGEHAIWGKH
ALFEESLHSPLIIHDPSMSNASQTDAIVETIDVFPTLCELANLPSPPKVDGESLVPVLKD
PASSEGEAVSYAKATTIRTSTHRLISHPKGFHELYDHETDPGETKNIADENLELVQQLHQ
RLKERLANRQQF
>B7PC69|iduronate-2-sulfatase|EC 3.1.6.13|Ixodes scapularis|TrEMBL
MQALCGPSRTSFLTSRRPDSLRLYSNHGHYWRRAVGNFTSLPQYFKEHGYHTVSVGKVFH
PGSMSGHHYDYPFSWSEEPYLPPSNKYENTKVTNFTFLS
>A1A5V0|iduronate-2-sulfatase|EC 3.1.6.13|Danio rerio|TrEMBL
MNVMFVFTCWWFVFIFHLLGRDVFAAKSKNFNVLYLIADDLRPTLGCYSDPVVKSPNIDQ
LASLSVVFHNAYAQQAVCGPSRVSFLTSRRPDTTKLYDFNSYWRVHAGNYTTLPQYFKSN
GYTTLSVGKVFHPGIASNHSDDYPYSWSVPPYHPPSFEYEKRKVCKDKDGTLHSNLLCPV
NVSEMPLGTLPDMENTEEAIRLLRSMKGSQKPFFLSVGFYKPHIPFRIPQEYLKLYPIEN
MTLAPDPDVPKKLPDVAYNPWTDIRKREDVQALNLSFPYGPIPKDFQLRIRQHYFASVSY
VDAQVGKILQTLDDVGLAKNTIVVLSSDHGWSLGEHGEWAKYSNFDVATRVPLMVYKAGV
SSRRSRPGAKTFPFIDVFQDTREHFGKGKIVNSVVELLDVFPTLANLAGLPSVHHCPSPS
FKMDLCTEGSNLANLIRNPKHLNREAYSFSQYPRPSDSIQENSDLPNLADIRIMGYSIRS
NDYRYTLWVGFDPLHCKPNMTEIHAGELYILTEDPGQDNNLFDEFGHAALLNKFGTMPSW
TESLKQHMMYFSSGLKSKGLS
>Q7UVD4|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)|TrEMBL
MTSLLSFSPKIAFNHIATTCRLFAPLAIAALFLRPALGDDRPNVLLIVADDLNCAIGPYG
DPNAITPNLDALANRGLVFDRAYCQQAVCNPSRSSFLTGLRPTTVGVDDLRKSFRETAPN
GASLVTLPQHFKNHGYYCQDIGKIFHNMGDTQDRQSWSMDEVLHAGTHAADTVHSNTPVA
LRARKLKKAPATETLDVPDTAYRDGQIARLAASVIRDYPDDAAPFFLGVGFWRPHLPFVA
PKKYWDLYDPDEISSPQLETSPVDVPDIAMHISRELHGYDGIPKEAELSPELKRHLRHGY
YASISFLDAQVGLILNALEASGHDNDTIVAFVSDHGFHIGEKTLWGKTSNFELDARVPLI
IADPRVDRTQPRTDCLTELVDLYPTLTSLAGIANDLPENLEGDDLSSLLINPNQTLKTAA
FTQHQHPFYAPREKWVALGYSVRTADWRYTQWRSIQDHHVIAEELYDHRNDPNESQNVAV
QFPDVVQQHSQSLIKHFNLSEKAPSAKSDF
>A0A157SB41|iduronate-2-sulfatase|EC 3.1.6.13|Bordetella ansorpii|TrEMBL
MGKIRNVLFIMADQLRADHLGCYGHPYLRTPNLDALAARGVRFTRAFVNSGVCGPSRMSY
YTGRYPSSHGTTWNRVPLSVGEVTLGEYLAGGGHKLALAGKTHVIPDKDGMARLAIDGGS
ELGELLARGGFVELDRYDGHHEPGEESGYPAFLRRHGYDSADPWTDYVIAGIDEQGQVVS
GWHMRNTHLPSRVQEAHSETAYMTDQALDFMRRRGDQPWVLHLSYVKPHWPYMAPAPYHR
LYTPDQCLPVSRNVRELQQAHPALQAYRQHEESQSFAMDECVRRVRPAYQGLIHQLDDHL
GRLFDDMEGAGRMDDTLIVFTADHGDFLGDHWLGEKELFYDTVQRVPFIVMDPSREADAT
RGQALHDMVESVDVVPTVLQALDLPVPAHRIEGRALQTLLHGRGEASWRDCVFSELDYSF
RQARLLLGKTPQNARAWSVRTDRWRYVYWLDEPEQLYDLQADPGEFQDLGRSAAHEAVRV
QLRRGLLDWAARRKRRTTLSDEAVAQATNAHKRAGVFFGQW
>A0A0P8C0C2|iduronate-2-sulfatase|EC 3.1.6.13|Phormidium sp. OSCR|TrEMBL
MITRRRLVNGLVAATAVGAGVNLLHGCGDRRTSDNPNRGRIGRDNYPNVLVLLIDDLRPQ
LNCYGRSEMVSPNIDRLAAEGTLFERAYCQVPICGASRASTLAGARATPTRFGSDYEARK
DEDMPNEPSLPLWFKNKGYRTISYGKIYHVIQDDADSWLEDPWRPRGMWGLESYVTPENR
AIVEAHGGTYGPPFEMANVANNIYTDGQIADRTVRTLERLQEGHAPFFLATGLFRPHLPF
NSPTPYWNLYQRENLSLADNPFRPAGAPDAALHNWGELRNYYGVPAEGRLSDEMALNLIH
GYYAATSYADALVGQILDALDRLELADNTIVILWGDHGWQLGEHGLWCKHANFETSLHAP
MIVRGPGIPAGQRTDALVEFVDIYPSLCDLSGLEKPEHLEGSSFVPLLDNPNLPWKEAVF
SYYNGGYSVKSDRYRYTEWKNDDGGGLGADVI
>A9HXE8|iduronate-2-sulfatase|EC 3.1.6.13|Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)|TrEMBL
MSKIQNVLFIMADQLRADHLGCYGHPYLRTPNLDALAARGVRFERAFVNSGVCGPSRMSY
YTGRYPSSHGTTWNRVPLSVGEVTLGEYLAGRERDLVLIGKSHVIPDQAGMQRLAIDGGS
ELGALLARGSFREADRYDGHHEPGDESGYPAFLRRHGYDSPDPWSDYVISAVDASGQVVS
GWHMRNAHLPARVSEPHSETAYTTDCALDFMRKRGSQPWTLHLSYVKPHWPYMAPDPYHR
MYSTDQCLPVVRNEQELAGAHPVLQAYRQHEESQSFARDECVRTVRPAYQGLITQLDTHL
GRLFDYMEGAGLMRNTLVVFTSDHGDFLGDHWLGEKELFYDTVQRVPLIVMDPSAAADAT
RGQVRRQLVEGVDIAPTILQALDVPQAGHRLEGRALQPLLHGEAQDTPWREAAVSELDYS
FRQARIALGKTPQQCRAWSVRTERWRYVYWRDEPEQLFDLRDDPHEFQDLGASASHAAVR
AELRQHLLDWSLRAKRRTTMSDEQVERSTNAHKRAGIYFGQW
>A0A6J8ERT3|iduronate-2-sulfatase|EC 3.1.6.13|Mytilus coruscus|TrEMBL
MNQWHRSLLLLVLVTISEGNLNVLLIVADDLRPSLGCYGYEPLITPNIDLLASQSVVFNR
TYAQQAICGPSRASFLTSRRPNTTHVYDQHTYWRKRGGNFTTLPQHFKNNGYVTFSVGKI
FHPGAASGKTDDYPYSWSFPPYHPSTQQYKMAKAILLPSFSNIRWLRSVPPAPSFNQLSN
IRWLRSVPPYHPSTQQYKMAKVSTHFTILQLSNIRWLRSVPPYHPSTQQYKMAKISTTYH
PSTQQYKMAKVSTTLPSFNSNIRWLRSAPYQISNIRWLRSVPPYHPSTQQYKMADQ
>A0A7W7YCW6|iduronate-2-sulfatase|EC 3.1.6.13|Prosthecobacter vanneervenii|TrEMBL
MRLPTLLATTVLVLASQLHAAQRPNVLFMMADDLNNSLGCYGHPLVKTPNLDKLAARGVR
FQNANCQFPLCGPSRNSMLTGLYPNSTGILTNSQVFRQSIPKAVSLPQAFRRDGYFAARI
GKLYHYGVPNSIGTNGHDDPASWELELNPAGADRLLEHPKIFSLLPGNFGGTLSWYASPE
PDEKHTDGLQAKDAEWVLERCAKEKDRPFFLAVGFFRPHTPYVSPEKWFKGYPEAQMPVV
QGVKEDQADLPAAALGSYKKEQDKLTDDLRRQAVQAYYSAISFMDAQAGKVLDALDRLGL
AENTIVVFTSDHGYHLGEHGLWQKQSLFEESARVPLIIAAPGMKQGAVAQAPVGLIDLYP
TLAELCGVKSPENLQGQSLAPMLKDPTVKGRGWVLSQVVRGGGFKRMGASAAKGDDGKRI
FGYALRTDRYRYTEWDEGKAGKELYDHETDPKELTNLADKPEQAEVQAKLAEQLHGIVKT
TFPADGVTPAIPQGNVMYNPELVDP
>A0A8B6DN57|iduronate-2-sulfatase|EC 3.1.6.13|Mytilus galloprovincialis|TrEMBL
MMNIWHGLLFLLVLLTISEGKLNVLLIVADDLRPSLGCYGYEPLITPNIDLLASQSVVFN
RTYAQQAICGPSRASFLTSRRPNTTHVYDQHTYWRKRGGNFTTLPQHFKNNGYVTFSVGK
IFHPGAASGKTDDYPYSWSVPPYHPSTQQYKMAKVCPGPDGKLYMNIVCPVDVIAMPEKT
LPDLQSTQHALQIMQNVSRFPEQPFFLAVGYHKPHIPLKYPREYLNLYPLDKIHLAPDPS
LPPKLPLVAWNPWADLRERDDVKMLNVSFPYGPLPKHYQLLVRQSYYAATSYMDDQVGQL
LKGLDQHNLSSTTVIVFMGDHG
>A0A7W5E3I7|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula rubra|TrEMBL
MNRAITTLLAFVYALGISHGLACAGQPRNVLIFFVDDLRPELGCYGVDSIHSPSIDALAS
EGVLFERAYCQQALCAPSRISMMTGQYPDHTGIVDLFTPLRKVNKTAMTLPLYFQQRGYV
TASFGKVYHHLRDDKTSWSEIPEPPSKKYADPNTLNGIAKRVREAKEQHLGVEKTRLAEK
GPPTECFVTEDEGYRDGVVANQAIASLRENKDKPFFMCVGFAKPHLPFAAPKRYWDLYKR
EQFTVPSRERPDGSPGLAFTIWGELRAYHGIPQEGELSDEMTRELMHGYAASVSFADAQV
GKVMAELDRLGLRDDTIVVLWGDHGYKLGDYGLWCKHTNFELDAHVPLIISAPTHSREQR
SKALVEIVDIFPTVASMTGGDVPESCDGKSLQPLLQNPDQKFRSFALTQYPRGSTMGYSL
RNDRYRYTEWIQAGTKRVIARELYDHQDTDTPSRNLADSPEQREHVFRLSQQLDAARRIE
NTNVNMKK
>A0A7X5XQ43|iduronate-2-sulfatase|EC 3.1.6.13|Sphingopyxis italica|TrEMBL
MRRTAHWTRRAMLALLITATSACSQAPAPRAGVKPTPTTAQRPNVLLILVDDLKPALGVY
GDRTAITPNMDRLAERGVRFDLAYANQAVCAPSRINLMTGARSTSSGIYNFGMNLRDYVP
DAVTLPQYFMRAGYHTESMGKVYHIGHGTVGDTAGWSVPHHKEKVIEYVDPASTGGKPTQ
EEALFEEIPVPEGNPFAYARTLARGAAWEMPDVADEAYADGRTAKRAGERLKALKNSKQP
FFLAVGFARPHLPFSVPKRYWDMYDPAKLPMPDFEQLPEGAPAYTDKQGGEINAYREPPR
NVRGDQFPPELKRQLLHGYYAGVSYVDVQIGKVLKALEREGLADNTVVVLWGDHGYHLGD
HGIWTKHTNMEQATHIPLIFAGPGIVEGRSTDQLAETVDIYPTLAALAALPAPTGPQPID
GISLAPVLHDPAARVRGYAYHAYPRPGRLGQAIRTDRYRLVRWTQEKTGARDYELYDLVA
DPQETRNQADALPKIRAELDAILDSQPAAQPINGKPRKN
>A0A7W8DRE6|iduronate-2-sulfatase|EC 3.1.6.13|Prosthecobacter dejongeii|TrEMBL
MHRLLCFLFVLATLHAAASASERPHILLICVDDLKPAIGCYGDPLAQTPNLDRLAARGMR
FDLAYCNQAVCAPSRNNLLLGSRSTSLGIYNLSDNFRQAVPGAVTLPQYFKSHGWHTEAI
GKILHTGHGNHDDEISWSVPPIKEKVIEYLDPANSADGKLTREEAYFTNQELNNIRDLPR
GAAWENQDVPDNAYADGRIADAAIQRLRKIKEKPEQRVFLALGFVKPHLPFTAPKKYWDM
HDRDAFTLPKRVTPPEGAPVYAGKTLGELNNYAPIPENPPLTPEIKRTLLHGYYAAVSFM
DAQLGRVLDELDAQGLAQKTIIVLWGDHGWHLGDHGMWTKHTNYEQANRIPLIFIAPDIA
APASSTRQPAETVDVLPTLVELAGLPPHTGPQPLDGTSLVPVLRDPSMRVRDHATHAFPR
QREGKPIIGRAIRTERYRLVEWKQPGAAANMADIELYDYQEDPQETRNMAPLQPAVVAEL
RAILDRQPEAKMKPNPKKK
>A0A7X0H6V0|iduronate-2-sulfatase|EC 3.1.6.13|Algisphaera agarilytica|TrEMBL
MRKTNAMILGWCFVALFILAVPVSAQPEPARPNVLLICIDDLRPELGSYGKDYIQSPHID
QLAARGRQFNRHYVQAPTCGASRYALLTGLYGPVGNKALSDRADRLNSGADVPPTMPAWF
RQHGYTTVSVGKISHFPGGRMGNGWNQDDRPELPQSWDRHLMPAGDWETPVGAMHGLAHG
EVRKKPGAMHVYQSAEGDDSIYPDGLITEEAIRQFDELAADSGKPFFLAVGFIRPHLPFG
APARYMQPYVGVELPPIPHPAKPKGVSTWHGSGEFNRYFLWDRDPNVDADFADEVRRHYA
ACVTYVDAQVGRLIERLEASGAAENTIVVLWGDHGWHLGEHAVWGKHTLYEESLRSPLIV
VSHQMQQQGVATDAVVETIDIFPTLSDLVGLANPEFADGRSLRAMLEDPAAVGHEAVSYH
HPGRTLRTDTHRLVLHNSGAVELYDHTTPEAETRNLAEEQPALAQALAERLDAKLPKRSP
AK
>E0W0K2|iduronate-2-sulfatase|EC 3.1.6.13|Pediculus humanus subsp. corporis|TrEMBL
MIIILFLTLLTYLPEVHLKLFNVLFITVDDLRPSIGVYGDLNAVTPNIDLLAKDGVIFKN
AFAQQALCAPSRNSFLTSRRPDTLHLYDFYSYWRKLEGNFTTLPEYFKENHYFTKSIGKI
FHPGISSGFTDDYPYSWSEPPWHPPSDIFKDAPVCLEGDKKFSNLYCPVKVSEQPMKTLP
DLESVQEAKKFLKHYKSVKPFFLAVGFHKPHIPFKFPEKYADLHPIKNITLPDLKYYPPG
LPTIAWNPWNDIRKRHDIARLNVTYPFASLSDEWIKKLRQGYYSSVSYVDHLIGEILKSL
KLHNLNKKTIVILLGDHGWSLGEHGEWSKYSNFDVAVRVPLIIRIPDTTYFTINRNATET
GSATVEEPVELIDIFPTVVDLVGLKSIPKCRDKSFSVKLCTEGNSLKSLIKTSIVEKSNK
KIMTMTSEWDKFALSQYPRPDVFPTKSPDSDEPKLNEIKFMGYSIRTKRYRYTEWIPWDS
KTLTGNWSNVNQTEFYDHHIDPNENLNLHGRPGLETLEKKLKYLLKKGFS
>F0SIU6|iduronate-2-sulfatase|EC 3.1.6.13|Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / IAM 15109 / NBRC 103401 / IFAM 1448)|TrEMBL
MRRLFCLPIFGIAAILSHAVSQADEAPNTSKSQPPNIVMIAVDDLNDWIGCMNGHPNAKT
PNIDRLAEQGTLFTNAHCQAPICGPSRASLFTGLRPSTTGIYLQINDHHIRDANEATKAC
TFLPDYFEQHGYKTLAAGKLFHNGDRAKVFDVHGTPSNMGPKPKKRFNYDPAWFEDRKGS
TQTDWAAYPEADEQMPDHRTASWAVDQLKEDHEKPFFLAVGFCRPHVPWYAPEKWFDQHP
LESIQTPPYTADDLNDVPAISLRLNDAPMMPTTEWAIENDQWKKIVQAYLACTTFVDHQV
GRVLNALDDSPYAENTVIVLWTDHGYHLGEKNRFAKQAIWEEATHVNLIFAGPQLPSHQR
CDAPVELLSIYPTLVDLAGLPANSQNEGVSLRPLLKNVNTEWPHVAITTYGRNNHSIRSR
NFRYVRYENGAEEFYDHRNDPQELHNLAADNRNREERFFIGRHLPEVNAPLATKSSYKFN
SYFIERMPMWRDGQD
>F0SJC0|iduronate-2-sulfatase|EC 3.1.6.13|Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / IAM 15109 / NBRC 103401 / IFAM 1448)|TrEMBL
MQGVRILIVALFCLWAMPSLAAERPNVLFIAVDDLRPELGCYGKEHIHSPNIDRLAQSGV
LFERAYCMVPTCGASRASLMTSLRPARNRFVNYLTRAEKDAPGIVTLNTHFKQSGYHTVS
LGKIFHHRDDNDHGWSEPAWRPSGVPSYQRPENQKLHAERQKQGRRSRGPAWESADVEDN
AYADGVLADKAIADLQRLAGQQEPFLLAVGFLKPHLPFIAPQKYWDLYDREQIHVPDNFH
PPKNAPKESIHSFGEMRAYAGIPAKGQVSEETARSLIHGYYACVSYTDAMVGKVLDELDR
LDLADNTIVVLWGDHGWNLGEHTLWCKHSCYETSMQIPLIVRTPGMVGGERRSGLVETID
LYPTLCQLAGIDAPHHVQGSSLVPLMNDANAEWKTAAVGRYQAGDTIRTDGFRFTQYTDG
KGKTTSRMLYNHQQDPHENVNIVADQKAEANQLQKELNQKKGKNSDRSK
>A0A2Z4LPD6|iduronate-2-sulfatase|EC 3.1.6.13|Muricauda aurantiaca|TrEMBL
MELKSKNFIALITLFIVVGCGFKSGKSLSLNSKSGTEANAEKQNILFIAIDDLRPMISSY
GETQMVTPNIDRLASEGIQFNNAFTNIAVCGASRASIMTGIRPSYRRFNDYTSRASTDVP
NAVTLNQLFKENGYETISYGKIYHHPDDNKEHWTEMDNGSKQNDYQDLNSIAKRLNGELG
SHGKKGPVIEYPDVSDYSYNDGKVTKKAINKLRELKTSNKPFFMALGYVAPHLPFIQPKK
YWDLYNHESIELAKNGYQPENAPYISMASQHYSSELRNMYLDIPKKGNLNDELSRNLVHG
YYASVSYMDALIGEVIQSLDDLGLRENTTIVLWSDHGFFLGEHGMWCKHSTFYEAIKIPL
IISSSKYKNNQTTQSMTELVDIYPTLCDIAQLDAPDYLHGMSLIPVLTNPEKILKTEIYT
RYKEGEAVVDIDYSYTEFYRDGQYLGNMLYNLNTDSEQNTNISKEPSAAALVVKYKEKLK
IMRDKVDKDPIQ
>E6XAT2|iduronate-2-sulfatase|EC 3.1.6.13|Cellulophaga algicola (strain DSM 14237 / IC166 / ACAM 630)|TrEMBL
MFKRCKIAFLFLVFISYQFHAQNQPTKKKPNILFIAIDDLRPELGTYGSEIAVSPNIDKL
ASQGLQFNKAYCQQAICGPSRASVMTGLRPETSGVFHNYIRFREKNPEVVTIPQHFISNG
YETVYYGKIFHHGDEDELSWSTPQLKKELSGNVKGFALAENQKIQEDTRKEMFDKYGDVA
KYGLAMGPAYESADVPDNTYIDGYNTDLAIETMKQMLKESDKPFFLGLGFNKPHLNWVAP
KKYWDLYDESQIPLTTLIDAPENGAAVGLQPSFELRVRSGIPKNGPIDEKLARKLKHAYL
ACISYVDAQLGRMITALDEAGIRDNTIIIVWSDHGWHLGEMGIWGKATNYEIATRVPLII
SAPNLPARNKGIKTNALVELVDIYPSLCELAGIEIPSNLDGKSFAPLLKNPNKKWKKKAL
SQFPSPALREWGAYPLRPAMRETYFGPLLEEVEIKIKNQMGKQWNRDLFENNLMGYAIRT
KRYRLITWRDRTKLSGQTIFTELYDHKNDPFEKNNIAEEHPKIVKKILKK
>E2XF59|iduronate-2-sulfatase|EC 3.1.6.13|Shigella dysenteriae 1617|TrEMBL
MRAIILLFDSLNKRYLPPYGDALTKAPNFQRLAAHAATFENSYVGSMPCMPARRELHTGR
CNFLHREWGPLEPFDDSMPELLKKAGIYTHLISDHLHYWEDGGGNYHNRYSSWEIVRGQE
GDHWHASVAQPPIPEVLRGPQKQTGGGVSGLWRHDWANREYIQQEADFPQTKVFDAGSAF
IHKNHAEDNWLLQVETFDPHEPFHTTEEYLSLYEDNWDGPHYDWLRGRVQESDEAVEHIR
CRYRSLVSMCDRNLGRILDLMDEHDLWRDTMLIVGTDHGFLLGEHGWWAKNQMPYYNEVA
NNPLFIWDPRSGVKGERRQALVQMIDWAPTLYDFFQQPVPPDVQGQPLAKTVSHDEPVRS
SAMFGVFSGHANVTDGRYVYMRAALPGREDDIANYTLMSCKMNSRYPVDEMRALSLAPPF
RFTKGLQVLRIPAQEKYKGLNQFGHLLFDLQNDPQQLHPIHDDVIESRMIALLIQLMKDN
DAPPEQFQRLGLA
>A0A173KVY9|iduronate-2-sulfatase|EC 3.1.6.13|Sphingobium sp. EP60837|TrEMBL
MVDISRRGLMAATAAFGIAASAIGARPKPTPRPNILWLVSEDNNPFIGAYGDRQAHTPAI
DALAAKGVLFRNVYSTAPVCAPSRYALITGASPEGNAPANHMRAQAKLPEGWRTTPEFMR
EAGYYTTNNFKTDYNCEIDEKAIWDDNSSKAHWSNRPEGKPFFSIFNFMTTHESQMFRAT
AGRLRPQDVTVPPHLPDTPEVRLDIASYYNLIEKMDGQVAKHLAALEAAGLSEDTIVFYY
SDNGGCLPKSKRYCSDAGLRVALVAYYPPKWQHLAPAGPGQALTAPVTLMDLPPTILRIA
GHLVPSQMEGRPLVKGASLPRYAFGMLNRMDERYDFVRSVTDGRWRYTRNYLPHLPSGQH
GAYEWQAKSYQSLEREYLAGRLTEEQARFFKPRPFEELYDLSSDPHELSNLAAHPSGREK
LKELRTGLDQHMLAINDNGFIPEGSPLEGYSSSRRAGAYPLRSLMALGAKAARRDAGNLS
AFVAGLNDRNEVVRYWNANALAMLGASASPAMGALQARLEVEPSAQVRVALAEAMGYVGS
ISRAESILLRLLEETASLRVKLQVVNALTHIGAKSDATLAVLKEALKLDDEYVPRAAIYQ
ILIMSGEYQPQVDTFAAYGRSPKG
>Q9VZP8|iduronate-2-sulfatase|EC 3.1.6.13|Drosophila melanogaster|TrEMBL
MITARLLLSLMMPVLLDAAAPPRRPNVVMVIFDDLRPVIGAYGDTLASTPYLDNFARGSH
IFTRVYSQQSLCAPSRNSLLTGRRPDTLHLYDFYSYWRTFTGNFTTLPQYFKEHGYYTYS
CGKVFHPGLSSNNTDDYPLSWSAPAFRPRTEQFMNSPVCPDKEGILRKNLICPVELQTQP
YKTLPDIESVAEALRFVGSRSRHSQEPFFLAMGFHKPHINFRFPRQFLSRFNLSQFYNYT
EDSLKPPDMPAVAWNPYTDVRARDDFKHSNISFPYGPISPLQAAQIRQSYYASVSYVDDL
FGKLIGGLDLDETVVVALGDHGWSLGEHAEWAKYSNFEVALRVPLIIRSPQFPVAQTKYY
HGITELLDVFPTLVDLAGLPKLDKCQSSQELTCGEGKSLYHQLMGLGRADEHVALSQYPR
PGMLPTKHPNSDKPKLRNIKIMGYSLRTDIYRYTMWVRFHAQNFSRDWHDVYGEELYDHR
LDSGEELNLMPLPQFDDVRQRLRRRLMEMVGS
>Q7URV9|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)|TrEMBL
MNEPFERQPRLLSPEPGPTPNRLKRFKRNLPLPIAPPRNMLRLILTLSLVLLSQSVDYAG
EKLNVLFIAVDDLRPELGCYESPIAKTPHLDQLAADGLLFNRAYCQQAICRPSRASLMTG
ARPDTTGLYHNYVSLRELQPNILTLPEHFVANGYDAAYCGKIFHQGDTDDGRSWNRESVK
RLDGIRKPKGGYALPENLKMKSDNMKSMLAKYGEAARRGLAAGPAYEKADVADTDYVDGY
NTAMAIATLKEMTQDNETPFFLAMGYKLPHLNWCAPSKYWDLYDANDIPMAVETDAPENG
AAMGLHASFELRTRAGIPKIGPLSPELSRKLKHAYLASVSYVDAQIGKLIAALEDAGVRD
NTVIVVWGDHGWHLGDMGVWGKATNYEIATRVPLMIWAPDMKARGATTDALVELVDIYPT
LCELAEINVPEHTEGTSFKPLMNNPNQPWKKAAFSQYPNPALREWAANPLSQGMRETWFG
PLIEQVEERIINQQGKAWDRELFEQHLMGYTMRTDRYRLVIWKDHRDPSASPIYVELFDH
ANDPNETKNIANEQPELTSQLMTQWNAGWEAAR
>Q7UWE8|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)|TrEMBL
MHALRPRCLFLGLICLFCSVPMSASAQETSPPKPLNVLMIAVDDLRPELGCYGKSYMHSP
NIDRLAASGMRFDRAYCQVAVCGASRASLMSGCRPETTQCWNFKTLLRSQMPDVLTLPQH
LSRNGYETGFLGKVYHSASDDAAAWTVDANEWAPRDRSKGKSYVQELPRKRNPANSSEKN
GPSIENGGDVPDSAYTDGHNADRAVALLERFSTQDKPFFLAVGFLKPHLPFNAPAKYWDL
YDRDDIKIPSREDVVDGLPYARSSWGELKNYTDIPAKTDMLDDEKTRELIHGYRAAVSYM
DAQVGKVLNALEANGQRENTIVVLWGDHGWYVGDFGDWCKHTNYEIATRVPLIVSAPGVP
AGETKSLVELVDLFPTLCELTELPVPEHCQGKSIAGVVHDPGLSVRPAAFSQYKKSKLGV
GPVLGTSIRTDRFRYTEYVSTKTGKLEDIVLIDFDKDPGATRNVASDPAYQPFLPQLHAW
CEQSATGL
>F0STA4|iduronate-2-sulfatase|EC 3.1.6.13|Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / IAM 15109 / NBRC 103401 / IFAM 1448)|TrEMBL
MSIRSLCLFYSLMFLTLPALTHAADKSTPEQPNVLFIAVDDLACTLGCYGDLLAKTPNID
RLAATGVCFERAYNQLPLCNPTRASVMTGLRPDQIQVYDLDRHFRDEVPDVVTLPQAFQK
ADYFAGRVGKIYHYNVPASIGTDGFDDPPSWQQTVNPIGRDKAEEDLIFNAEPHRKISAA
LSWLAADGDDTEQTDGIIATEGIRLMQEHQDEPFFLAVGFFRPHTPYVAPKKYFDMYPLD
SIRLPYAPEDDRADIPTAAFAHNCPIPHYNLDHDTLLKATQAYYACVSFIDAQVGRLLDA
LDQLQLTDNTIVVFWSDHGYHLGEHNGIWQKRTLFEQSSRSPLIIRAPGKAGNGTPCRRI
VEFVDIYPTIAALAGVSAPENLAGRDLTPLLNDPNRDWDSYAITQILRPDDDRLPEEVMG
RSIRTERYRYTEWGEGKHGRELYDHHADPQEFHNLAIDPDEAAKRLMQKLRPLLDQHAPG
RKTETPVNPARL
>G8NTZ8|iduronate-2-sulfatase|EC 3.1.6.13|Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8)|TrEMBL
MPNQSQKRTTRRQFIAQAAGTAIAGALTASASAREIKKPNVLFFMSDDMRVELGCYGSHF
RAQTPNLDALAQQGVRFDRNFCQFPLCNPSRASLLTGQVPLDTKVLGNRTNFRDTRPDLT
SLPQLFREQGYVTARTGKIFHGGYDDPKAWTVGGSDVSIAAIEAASEQSDEDTQGKYHQH
REIIPPQSVPPPPPGIPVSKTQDPRAAHSDEILILDGDGGEHPENRVAETAIGYLRTYRD
KPFFIGCGFSKPHSPPTAPQRFFDLYDPAKLELTPDFEAWPTVPPGFPKAAIRPRNADLF
IGRGASTTEAKEVIRAYLASISWVDWNLGRVIHELDALGLRDNTIIVFVADHGYQLGEKG
KWSKAGSLFEMGTRVPLIIHDPRAAGNGQTSTRLVQSLDIYPTLVELCGLSRPSSGLQGA
SLTPLLHRPQSTWKRPAFSLWSEDGKTIHGLAVRQDHWRYVEFGADGKNGSMLFNEQSDP
LEMHNLAEDPGHAGIRDNLSKLTAAYRDRTRLA
>Q7UW58|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)|TrEMBL
MLITNVVGFARLYLPHKSLSPCLNPRAEVALMNLKRIFGLGLLLGFALSSQFSFGQKPDA
KKASQRKNVLFLISDDLNTRIGCYGDPIVQTPNIDRLAARGVLFENAACQYPLCGPSRNS
MLCGLYPDTTGIHGNAQIFRDSIPERWSLPQAFRLDGYFAGRVGKLYHYNVPKSVGTNGH
DDPASWELELNPAGCDRLIEEPDIFTLRKGAFGGTLSWYASPRPDEAHTDGMLADDASWV
LERCAKRNDRPFFLAVGFYRPHTPYVAPKEYFEPYKLEDMPLFDNVEEDNADVPAAALLS
KKKEQDLLNDELRRQAIQAYYASTTFMDAQVGKVLDTLKRTGLDKNTIVVFTSDHGYFLG
EKGLWQKQALFDKVAGVPLIIAEPGRTEGAIAKSPVGLVDLYPTLAELCDVPTQKLMQGQ
SLVPMLRDPSQTGRGYSMSMVARNDRQTKQRYYGYSIRTERYRLTLWDDGKRGTELYDHQ
NDPEEFTNLAHGERKNDPNNAKVIRELTEKLKAEMANGMPASGKRTEYKVGNWNPMLRID
N
>Q7UYA8|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)|TrEMBL
MLGSIETVQPKATEMPSSLSAISFRAAVMLACLSTHAVGLADHHDVYLLAGQSNMDGRGQ
VSDLSEEQKQSTGDAIIFYRSVPRESDGWQTLAPGFSVPPKYKGDLPSPTFGPEIGFARS
MSNANPNQKLALIKGSKGGTSLRADWKPGVQGDPKSQGPRYRDFIETIRMATKQLSDRGD
QFTIRGLLWHQGESDSKSSTERYRRRLEELIVRIREDVGVPDLPVVVGEVFDNGKRDNVR
TAIQAVAAASSTVGLVSSEGTTTWDPGTHFDARSQLLLGERYAVAMSELPAPIPATGSST
SVQQRTDRPNVLFITVDDLNDWVGCLGGNPDAQTPNLDRFAQQSVLFNNAHCQVALCYAS
RASFMTGMYASKTGIYNNSSKSARDAYHRAKQMPVWFGESGYRTMCMGKIYHNDHGKKAY
WDEIGPKTLRWGPEPPNGRQFTKRFGKDAQDSLAWAALDIEKGGMPDEQIAAWGIEKLDQ
EYDQPFFLSLGFYKPHTPMTAPKRYFEQFDRDSLTLPNVLENDLDDVPEIGRRWVLDRSK
LIAEEAVKQYSPTYRRELVHAYHACVALIDDCIGQVLRKLDNSPYANNTIVVLCSDHGWH
LGEKNHWRKWMPWEESTRSLLIVRTPDAAGSGQVCQRTVGLIDIYPTLAELCELSPPDGL
QGLSFRKLLDNPDGPWDRPALTSTKAGNHTVRSDRWRYIRYIDGSEELYDHDVDPNEWHN
LANDPSMNSIKKQHAEWIDRLTESN
>A0A2Z4LNB2|iduronate-2-sulfatase|EC 3.1.6.13|Muricauda aurantiaca|TrEMBL
MKFKHLYIPIIAVFTLAVLACNSKKKEIRENTVLVENRPNIIWLVAEDLSPRFAAYGDSL
AHTPNIDQLASNGIVYENAFTVSGVCAPSRSSMITGMYPTSIGTQHMRQKSGVIDIPGFP
KYNAVPPPEVKAFPEILRKNGYWTASYKKLDYQFGEPFTIWDEVSAYPSWRNRPEADKER
PFFIYYTFEITHEINIWPDSTKNRFFDEFNIKRPNLAPDVRKRPAFDEENSVAPEAVVVP
PFLPDTRTSRSHIARLYDNVSRMDVQIGEVLKDLEEDGLLENTIVMFMSDHGDCLPRSKR
WIYDSGIKVPLIIHYPEKYLPKNREQPSRDKNLYSFVDLAPTVLELAGVEVPQWVQGKSM
VTELAQNPRDYVYAARDRMDNRYDIRRAIRDKDYKYIKNFTPEVPYSQEITFLNQMPLMT
EIKRMDKLGTLNRNQSYWLKRPKPSEELYNLNDDPFELNNLASSPSYSETLERMKIALEY
WQNTYGDLKDVPEMEQAELMWPGGEQPKTKEGKLIFKNDSILLECETEGATIAYRTNDTE
RWLIYDEPLSREKIYKIEIKTVRYGYEESEPISYEVPSN
>A0A8B6BUL2|iduronate-2-sulfatase|EC 3.1.6.13|Mytilus galloprovincialis|TrEMBL
MKGLWIFVIVNILAISKGRKNVLFIVMDDLRPQLGAYNGPYFPGSGQSLMHTPNIDGLAS
KSLLLKRAYVQQALCSPSRASFMTGRRPDTTHVYDLYTYFRSVGGNFTTIPQYFKSKGYE
TAGMGKIYHPGVDSNNNDPLSWSMPYLRGDHNWEDKNHSWKGIPDSLLKDRPLIDKQIAD
HAINTLQHLAPAAKSGHKPFFLAVGFYRPHLPFVFPQSFIHNYPWSDVHVPDNQFAPRSM
PTIAWTHSNELWSYQDIKDTKFTGDINTTLPHATVIKLRRAYYTSVSWVDSLIGNVLAEL
SRLGLDSNTVVSFVGDHGWKLGEHGAWAKHTNFNVDTHAPMMVKIPGMTDKGIVSEKLTE
FVDLFPTLVEAAGVSPVPLCPENSATVSVCHEGQSLIPLIKNPNIAWKNASFSQYPRRHS
HHDIMGYTITTDRYRYTEWVRFNKPTYKPDWNTVVDAELYDHQVDPNENINKVHYHSQSN
IKMQLSQQLRAGWRDTLPSSAISHGFGR
>A0A7W5H520|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula rubra|TrEMBL
MDSSIPTLKRMLGIACTLVFACFVHAADQPNILFIAVDDLRPELGCYGSPIAVSPNLDAL
ARDGLLFNRAYCQQAICRPSRASLMTGARPESTGLFHNYVSLRELQPDIITLPQHLIEHG
YETVYTGKIFHQGDTDEENSWSREPVRKMPGVKKPSGGFALPENQRIQSEDRKAMIAKYG
EAAKRGLASGPAYECADVPDHAYVDGYNTLQAIATMKELAQQPDKPFFLALGFKKPHLNW
VAPKRYWDMYDPAEIPMAEEDHAPSAGASMGLHASFELRTRAGIPKSGPLGPELSRTLKH
AYLACVSYVDAQIGKAIAALEEEGLRDNTIIVVWGDHGWHLGDMGVWGKATNYEIATRVP
LMIWTPGMKTRGAKTDALVELVDIFPTLCELSGVPIPDHVEGHSFVPLLENPTLPWKTAV
FSQYPNPALREWAANPLSPAMRETWFGPLITEVETRIEQQFPDVWQRDLFEQHLTGFAMR
TDRYRLVVWKDRRDLAADPVFVELFDHETDPRETTNLATENPDVVNALMDQLHAGWEAAL
>M5RFS0|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula maiorica SM1|TrEMBL
MTGLRPQTIGVYDLPTHFRLATDEMTAQDPQRGDVVTLSQHFKNNGYLAQGLGKIYHIGH
GNIDDKASWSVPSWRPKGPSYVLDANLKNIVPDSKGRKRGPATESADVSDETYGDGKIAL
ETIERIAEAKKNPQQPFFIATG
>G0L8L6|iduronate-2-sulfatase|EC 3.1.6.13|Zobellia galactanivorans (strain DSM 12802 / CCUG 47099 / CIP 106680 / NCIMB 13871 / Dsij)|TrEMBL
MNGIKNLLLLVLAISLYNCGGTDKPQPKKESTRPNILFIPVDDLRPELGSYGNDFVKTPN
IDRIAQQGVVFMRAYCQQAVCNPSRASLLTGLRPDSIRVWDLSTKLRNNVPDVVTLPQYF
KQNGYITVGLGKTFHNDIQDSVSWTERPHLEGFPFDPDAVYASKRNTDIQEEKKQKLIAQ
GKIRLDPLGHWYLKANSTENADVPDDAYYDGAQTTYAVDKLEVLAAQEKPFFLSVGYYKP
HLPFNAPKKYWDMYHRDSIPLAENQSLPKGSPDFAVHGDQELRYYDDNHDLPRPNEAPWN
EDRQREVKHGYYASVSYIDAQIGRLYDKLEKLNLLDNTIIVLWGDHGWKLGEHNGWGKMS
NYEIDAHVPMIISGAKVKAKGSKTNALTELVDIYPSLCEMSGLPVPAHLQGKSFVPLLAD
PSIKWKAAAYSQFLLGRFGPAETRQEERMGYSVKTDRYRYTEWYTWNKNQKQKGDYISSE
LFDHENDPGENYNIAQEPSNSQLIKQLASNLHKNF
>A0A061HUM4|iduronate-2-sulfatase|EC 3.1.6.13|Cricetulus griseus|TrEMBL
MELTITRGRDEGQAGGCECCGRAGGASVRPRNHSLSKIANGPDLIKAYFKCELGRQALGP
YFCYTFTKITYDPCVLLDRGLQMACDYVVLLIWFYESGVCGQALEDKNYKYRGPTEAIFQ
MNFLELPGLSLRCRLEEMIPHQKPLSQPLKNCLFSLDVSIKSHLGTELIRSFDFFVLELF
VSFYECSYSACMHVCGPHVCLLLQKSEEGFRFPGTGVMDGYSLNVLLIIVDDLRPSLGCY
GDNLVRSPNIDQLASHSVLFQNAFAQQAVCAPSRVSFLTGRRPDTTRLYDFNSYWRVHSG
NFSTIPQYFKENGYVTMSVGKVFHPGISSNHSDDSPYSWSFPPYHPSSEKYENTKTCRGQ
DGKLHANLLCPVDVADVPEGTLPDKQSTEEAIRLLEKMKTSASPFFLAVGYHKPHIPFRY
PKEFQKLYPLENITLAPDPQVPDGLPPVAYNPWMDIREREDVQALNISVPYGPIPVDFQR
KIRQSYFASVSYLDTEVGHLLSALDDLHLTSNTIIAFTSDHGWALGEHGEWAKYSNFDVA
TRVPLMFYVPGKTAPLPGAGEKLFPYQDPFDSTSELMDSGRHVMDLVELVSLFPTLAGLS
GLQVPPRCPIPSFHVELCREGQSLQKHLQLHDFEEDSYFLGNPRESIAYSQYPRPADFPQ
WNSDKPSLKDIMIMGYSIRTIDYRYTVWVGFNPAEFLANFSDIHAGELYFVDSDPLQDHN
VYNDSQHGGLPHSLKP
>A0A6J8ES00|iduronate-2-sulfatase|EC 3.1.6.13|Mytilus coruscus|TrEMBL
MVPVRSVPPYYPSTQQQYKMAKVGTTHHPSTQYKMAKVSPNHYPSTQQYKMAKVCPGPDG
KLYMNIVCPVDVTAMPEKTLPDLQSTQHALQIMQNVSRFPVQPFFLAVGYHKPHIPLKYP
KEYLNLYPLDKIHLAPDPSLPPKLPLVAWNPWANLRERDDVKMLNVSFPYGPLPKHYQLL
VRQSYYAATSYMDDQVGQLLKD
>A0A7W5E3D0|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula rubra|TrEMBL
MIRSAALLIVVCVLIGGVGPAHAEAESRPNVLMILVDDLKPTLGCYGDVHAKSPHLDALA
ARGMRFDAAYCNQAVCAPSRFTLMLGAHSTSTGLYGLGSHLRKLVPDAVTLPQYFQRHGY
RTESMGKVFHIGHGNHGDPDSFSVPHHHEKVIEYVDPESTPSGELTREEAFFTNHRVADN
NSLPRGAAFESPDVEDNAYADGRIAELAAARLRHAKQRRQADGTPFFMVVGFARPHLPFS
APKKYWDMHDRESLPMPVVKTSPLDSPIEAGKPNGQGEIRNYFPVPDKNSPAAIDDQLTR
TLIHGYYASTSYVDAQIGKVVAELDRLELSDDTIIVLWGDHGFHLGDHGFWTKHTNYEQA
ARIPIFIVAPGVTQPNSQTAQLTETVDIYPTLAELAGLPNPTGPQSIDGVSIVPVLKDGN
ARVRDHAYHVFPRFGLGRAIRTSRYRLVEWSKPAAPERDATYELFDMKTDPNETRNVANE
QPSVLRSLLQILDEYPSPHANL
>A0A1J0LK37|iduronate-2-sulfatase|EC 3.1.6.13|Flavobacteriaceae bacterium UJ101|TrEMBL
MMKNLLTYNLFLWIFLCCSSCSSKKDETTQKKHPNILWIVSDDLGTDLGCYGNSLVKTPH
LDQLAKQSILFTNMHSVTAVCSPNRSSLITGVYPTSIDCHQHRTQFKKPLPDSIRPITDY
LKKAGYFVSNGDSKNKSKKGKTDYNFIHNSDSLFDGTHWSQRKKGQPFFAQIQIYNPHRP
FKRDTLNPINPDFIQLPPYYPNHKLAQKDWAYYLESVQLVDREVGKILKDLENDGLLDNT
IIFFFGDQGRPHLRSKQFLYDGGINTPLLIKGIKNKKGIVDTQLVSTVDIPAMTLALANI
SIPNYIAGLNILDSTLSRNHIFSMRDRRDETVDRIRAIRTQNFKYIKNYYPNRPYTQPNV
YKKFQYPMLTLMRVLSKQKLLTPEQAQFLATNRPKEELYDLKNDPFELYNLAEISQFQTQ
KDELDSLLKYYVKKYDQGVYPEPKSETDYASKIMQERWIKRMKKRGLSPNITDEEYLEYF
EKNY
>F0RBY0|iduronate-2-sulfatase|EC 3.1.6.13|Cellulophaga lytica (strain ATCC 23178 / DSM 7489 / JCM 8516 / NBRC 14961 / NCIMB 1423 / VKM B-1433 / Cy l20)|TrEMBL
MKKLIKIICFILITTSCYSQKKPNILFIAIDDLRPELGCYGSNIAITPNLDKLATEGLLF
NNAYCQQAICGPSRASVLTGIRPETSGVYHNYIKFRDANPNVVTLPQQFKNNGYETVYCG
KIFHHGDLDDGLSWSRQPAIDSMLLKNIKRPGGFVLEENNKDRKEQRAKMIAKYGEVAKY
GLAMGTAYENADVADNEYLDGYNTELAIATMKEMATNNKPFFLGLGFNKPHLNWTSPKKY
WDLYNPNTIKLALEKQGPKGGAEMGLHASFELRTRSGIPKKGELNNNLAVTLKHAYLACV
SYVDAQIGKIITQLEKEGLRDNTIIIIWSDHGYHLGDMGIWGKATNYEVATRVPMLFWAP
NMPKKSSGKKTNALVELVDIYPTLCSYANIPVPNYVEGYSFKPIVNKPTKKWKTAAFSQF
PTPALREWGAYPLRPAMKETFFGPLIKNVEARIIHQQKGKWNRNVFENTLMGYAMRTKDY
RFIVWKDKHKPKNEPIFIELYNHKLDPSETVNIASKNPKLVKKLMLQFTKGWQGNKPKLK
>Q7UJQ7|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)|TrEMBL
MQNGRAIPLFHASMPPNQPPHPLRSSKANQPDNQSKDRTRRRTSHHPPSIRETIRIDSPI
PHADSLLPMLSQLQKTVTFLALLGCFSVGSMAGVQADERPNVLLILVDDLKPALGCYGDS
IAKTPNIDSLANRGMRFEMAYCNQAVCAPSRFTLMLGSHSTSTGLYGLGSQLRQIIPDAV
TMPQHFAKQGGYRTESLGKTFHIGHGNHGDPESFSVPHFKEKVIEYLEPASTDGGQLTRE
EAYFTNQMLGRIKTLPRGAAYESPDAKDEDYADGRVAAETIQRLQAAKQRQKTEGTPFFI
ASGFARPHLPFSAPQKYWDLYDPASLPMPTHETLPVDAPKVAGKRGGEISNYKPVPTEPN
ADFDDELKRNLIHGYYASVSYVDAQIGKVIKELDRLELLDNTIVVLWGDHGFHLGDLGIW
TKHTNYEQANRIPILITAPGVTQPGSSTKQLAESVDIFPTLSELAGLPAPSGPQPIDGVS
LVPVLKDSSARVRDHAYHAYPKRQLGRSIRTERYRLVEWKAFDGKGDTAYELYDYQTDPN
ETKNLASDRPEVVQRLTKILAKYPAPAKRKR
>F0SJJ5|iduronate-2-sulfatase|EC 3.1.6.13|Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / IAM 15109 / NBRC 103401 / IFAM 1448)|TrEMBL
MQLITRFTLTCLFLCGTWLLPAMSTAAEQKPNVLMIVSDDLTCCLGSYGNDVCRTPNLDR
LAETGVRFTRTYCQYPVCGPSRASFMSGLYPEQNGVLGNNYTEGSYRTITPELADHPSLG
GFLRRNGYVSLRVSKIYHMGVPGGIEAGSSGGDDPDSWDEAFNIMAPETASPGKLELLSP
KKKHYGSNFARIQVPDGMEGTQADYLAASQAIAILENRARTRIPPVRNSLKPGDPFFLAV
GLVRPHVPSVAPQRLFDHYDEKLIQLPYVPEGDLNDIPRLAAAMQNEPRYGMNETQKRQA
IAAYYASVEFMDEQVGRLLDTLDRLQIRDNTIVVFTSDHGFQLGEHEMWQKLSLFEASTR
VPLLISAPGYEQTAGTASDELVELLDIYPTVADLVGLKAEAPQNLAGHSLRPILADTNAS
LPREFAYTVTHNGGRSLRSAAWRYNIWKDGSEELYDLKSDPQQFHNLAQDAAHAEQLQLM
QRELERKRSELSRK
>A0A7X0HAU6|iduronate-2-sulfatase|EC 3.1.6.13|Algisphaera agarilytica|TrEMBL
MPRYILALFAATLMLAPTLHAAEPGSQRPNVIFIITDDLNDMIEGYDGHPRVITPNLAKL
AATGTSFTHAYCTTAICAPSRTSMMTGIHGHNSGSLWFDTWWKNETLANSHTIGSFFREN
GYHTAGSGKVSHVPHHKRWDEWHKDPNYGPHAWNGKERVGNPHLPAPFNTLGKNNGGFGP
TSLVPWDGEDGKGWVASPGSTPPLWRYVNEDDRDPTPDEANAQWAADFLDAYPSRDIDKP
FFLAVGLIRPHSPTHAPDRFFDMYPLEDVELLPNKPNDMDDTGYPAVFPLDKRGYHIAYQ
HLINSYSTAAEGLQRFVQSYLACVTAMDENVGQVLDALERSPYRDNTIVIFTSDHGMHLG
EKDHLFKLTLWEESVRIPLIVYAPGLTPAGSKASAPVSLIDLFPTLIDLCDLEGDTRMSD
KGLPLDGHSFKPLLKDPENGTWDGPDAALSFLYSGGWAEDSHHNWSLRTEDFRYIRYRDG
GEELYDHRVDPQEWTNLASDPEHADTIEAFRARLEEQVPEAWVPMLPKSARN
>K8YWM3|iduronate-2-sulfatase|EC 3.1.6.13|Nannochloropsis gaditana (strain CCMP526)|TrEMBL
MPEGNFTDGLVVDAAIERLRGHVHAQSVEGRGDRPFFFAVGIRKPHLDWAVPKAYFDAQV
SLRDVRLPSDSVRVAPPGMPAVAYYNCSTEPPWKLAMPEIVLSPHEPLQDELERELRRAY
YAAVTWMDANVGKLLDALTELGLDENTAIVFHSDHGFHLSEEGMWCKQNTREIGTRVPLL
VSAPGLTVPSEARREKEQRETAGLSEAIVQLVDIYPTLLDLAGLTLPDPNMRGRSLIPLM
RRWGSGGNETENATGFGAAFSQYPRCASTSLAPSGLASQGYRWNRQCAWLENDKIDVMGY
SVRVEGWRYTEWYTWEARRARPRWNAAGLVAVELYAMDMSRGKGVMEEMKMEDKVARNVA
NDVRYRQEQEHLSKLLYDHFSSFQPFAMSADAVDT
>U2DHD3|iduronate-2-sulfatase|EC 3.1.6.13|Halorhabdus tiamatea SARL4B|TrEMBL
MVTAPELLSDIGYHTVGVSENGYAGVAKEFDKRFDDFVKSSPSSLSDFISYQQALSFLKY
SLQTRKHGPGLSVDVGAHGDQNSFFTTDITKRKLRNASVQDCPIFAYVHYNDPHHPYIPP
LAYRDEYLEDIDVSADEAVAFAERMHEDLYKWIANDLPLSEKEWEILYAMYDATIRYTDA
MVGNLFNFVQEQLDDTIVVITADHGDLFGEYGLLGHHMVLHDGVIHIPLVTHGLEGVIDH
SEQPTQHIDVMQTLLAAVGADTTQFQGYDIRDESRDIAISQDLRGTVENGDTANYERIRQ
YNADVDLSHLPKSMVSSFRTTEHKLVRTDEWTRLYELQDETTDVSDEYPDVLEELDSFAD
DWMAAEGQSFKVDPEEADLSEQTEQHLQDMGYM
>A0A6J8DIS9|iduronate-2-sulfatase|EC 3.1.6.13|Mytilus coruscus|TrEMBL
MNLWHRRLLLLVLVTISEGNLNVLLIVADDLRPSLGCYGYEPLITPNIDLLASQSVVFNR
TYAQQAICGPSRASFLTSRRPNTTHVYDQHTYWRKKGGNFTTLPQHFKNNGYVTFSVGKI
FHPGAASGKTDDYPYSWSFPPYHPSTQQYKMAKQYKDGRRLIPSIQQYPRSVPPYHPSTQ
LQYKMARNIRWLRSVPPYHPSTQQYKMAKVCPGPDGKLYMNIVCPVDVTAMPEKTLPDLQ
STQHALQIMHNVSRHPVQPFFLAVGYHKPHIPLKYPKEYLNLYPLDKVHLAPDPSLPSKL
PLVAWNPWADLRKRDDVKMLNVSFPYGPLPKHYQLLVRQSYYAATSYMDDQVGQLLKGLE
KHNLSSNTVIVFMGDHGWSLGEHQEWSKYSNFEVATRVPLIIYVPGLTNKGQNLHRKFIF
DRNFINNDNYRVTNALVELVDVFPTISELSGIKVPELCPDNDSDIELCTEGTIQNTCGYC
NTTRPLSVSRYRNDSMREQRTKSIRKPGYNTLPNRKYTTNTIPVDMFANERSARAIVRVV
ERLVHVQNCKEDVDNIYENLIDLVTDEMNEN
>Q32KJ4|iduronate-2-sulfatase|EC 3.1.6.13|Rattus norvegicus|TrEMBL
WRQLSFSLLLGFFCIALVSAAQGNSATDALNILLIIVDDLRPSLGCYGDKLVRSPNIDQL
ASHSIVFENAFAQQAVCAPSRVSFLTGRRPDTTRLYDFNSYWRVHSGNFSTIPQYFKENG
YVTMSVGKVFHPGISSNHSDDYPYSWSFPPYHPSSEKYENTKTCKGQDGKLHTNLLCPVD
VADVPEGTLPDKQSTEEAIRLLEKMKTSVSPFFLAVGYHKPHIPFRYPKEFQKLYPLENM
TLAPDPHVPDSLPPVAYNPWMDIREREDVQALNISVPYGPIPVDFQRKIRQSYFASVSYL
DTQVGHLLSALDDLRLAHNTIIAFMSDHGWALGEHGEWAKYSNFDVTTRVPLMFYVPGKT
ALLPAAGEKLFPYQDPFDPASELMGAGRRTEDLVELVSLFPTLAGLAGMPVPPWCPIPSF
HVELCREGHNLQRYLQLHDLEEDPYLFGNPRELIAYSQYPRPADFPQWNSDKPSLKDIKV
MGYSIRTIDYRYTVWVGFSPTEFLANFSDIHAGELYFVDSDPLQDHNVYNDSQHGGLLLS
LRP
>A0A7W5E2D0|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula rubra|TrEMBL
MKQLFLLATTLLFLTSIANAQSPRKNILFIGVDDLRVELGCYGAEHMKTPNLDALARQGL
LFEQAYCQQAVCAPSRISLMTGMRPDSTGVFDLDHPLNQALPDAMSMPRFFKENGYRTVA
FGKIYHHGRDDKAFWDVLDACSTPQYTGAETVAVITEKTKEARKQKLKGKEFRQFVKGPA
FESSDVTDSTYSDGVIADNAIEQLRQKDDRPFFLAVGFKKPHLPFVAPQKYWDMYAPAEI
KIPARTPPRGAADQATTTWGELRSYSGIPAKDDLSDEQTRTLIHGYRACVSYIDPQVGRV
LEEVDRQGLRENTIIVFWSDHGWKVGEYGDWCKHTNFELDTHVPLICSGPGIPTGQRSKA
LVEYIDIYPTLAAWCGLNTPKSCEGESLLPLFADPTLPGKRAALSQYPRGGGMGYSIRSG
NWRYTRWQRKNGELIARELYDHSRSDIATENVAELPENTVTVNQLDARLLEIIKPTNASR
>F0SFV3|iduronate-2-sulfatase|EC 3.1.6.13|Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / IAM 15109 / NBRC 103401 / IFAM 1448)|TrEMBL
MLRLTLCASLLLSGLVFSSSASFAADAAAEGDSRPNVLFIAVDDLNDWIGQLGGHPQSKT
PNIDRLAERGVLFRKAYCAAPACNPSRVAIMTGRRPSSTGVYTNPDPWRKIIPDAVTLPQ
HLQKNGYYTVGSGKIYHGSFPDPASWDEYAPSKTKQTFGDLYKKPKNANGLDKSHFDWAP
VDATVAETGDAQTVEFVTAQLQKEWGQPTFLACGIYRPHLPWFAPKEFFDQYPLDQIQLP
EVPQGDLDDIPAAGVKMARPEGDHAAVVKNDQWPNAVQGYLASIAFTDHLIGKVLDAYDA
SPNKDNTILVFWTDHGWHLGEKQHWRKFALWEPATRVPLIIVTPEMQNAGEVCDQPVNLV
DVYPTLLELCGVERQADLEGRSLVPLLNNPAGKNGSPWYSLTTHGRNNHAVRSKDLRYIR
YADGSEELYDHRTDPEEYQNLAGNSNMSDVLQELRAQLPQENVAEWKKQNKNPKAGNAVK
QKNKKQSSAAGK
>R7ZWZ1|iduronate-2-sulfatase|EC 3.1.6.13|Lunatimonas lonarensis|TrEMBL
MPGTDYYEQLIQKAREAAAFGIIKGVIWHQGESDLGKLDTYMSDLEKLIQRIRADMELPQ
LPFVAGEIAEDQPGRDAFNRLLMQLPGQVPHTAVVSSKGTKTFDEVHFDTKSQLKLGKRY
AQKMKNLTHPTHEL
>A0A6J8DLB2|iduronate-2-sulfatase|EC 3.1.6.13|Mytilus coruscus|TrEMBL
MNLWHRRLLLLVLVTISEGNLNVLLIVADDLRPSLGCYGYEPLITPNIDLLASQSVVFNR
TYAQQAICGPSRASFLTSRRPNTTHVYDQHTYWRKKGGNFTTLPQHFKNNGYVTFSVGKI
FHPGAASGKTDDYPYSWSFPPYHPSTQQYKMAKVCPGPDGKLYMNIVCPVDVTAMPEKTL
PDLQSTQHALQIMHNVSRHPVQPFFLAVGYHKPHIPLKYPKEYLNLYPLDKVHLAPDPSL
PSKLPLVAWNPWADLRKRDDVKMLNVSFPYGPLPKHYQLLVRQSYYAATSYMDDQVGQLL
KGLEKHNLSSNTVIVFMGDHGWSLGEHQEWSKYSNFEVATRVPLIIYVPGLTNKGQNLHR
KFIFDRNFINNDNYRVTNALVELVDVFPTISELSGIKVPELCPDNDSDIELCTEGTIQNT
CGYCNTTRPLSVSRYRNDSMREQRTKSIRKPGYNTLPNRKYTTNTIPVDMFANERSARAI
VRVVERLVHVQNCKEDVDNIYENLIDLVTDEMNEN
>A0A7W5DUN5|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula rubra|TrEMBL
MAALLTAVGHVGANASDPVTTETSATTTSADRPNVLFLISDDLNCRIGCYGDPNVQTPNL
DRLAARGVRFENAYCQFPLCGPSRNSMLCGLYPDSTGILANSQIFRETIPQHQSLPHAFR
LDGYFAARIGKLYHYNVPRSVGTNGHDDPASWEMEINPMGCDRSLEESEIFSLRKGSFGG
TLSWYASPRSEEMHTDAMLAEEADWVLERCAKRADRPFFLAVGFYRPHTPYVAPKKYFES
YDLDNMPIVDDVEEDRVDLPPASLLSHKADHDLLTDQLRREAIQAYYASITFMDAQVGKV
LDSLEKHGLADNTVIVFTSDHGYHLGAKGLWQKMSLFEESARVPLIIATPEGTSRGETAT
SPVGLIDLYPTLAELCDVKPPANLQGQSLRPMIDDVDEPGRGFTISQVTRKLPKQKSRFF
GYTIRTPQYRLTLWDDGKNGVELYNHQTDPTEKNNLAFDGDQTDSMTRDADTLATIQKLS
NMLRKEIARGIPEDGRPAVKTRKWVIDLTNP
>A0A840E3M2|iduronate-2-sulfatase|EC 3.1.6.13|Lewinella aquimaris|TrEMBL
MKVRPWPFLLYVILCLLSVGSRGNAQTTVKPNVLLICVDDLRPELGSFGAEHISSPHIDA
LAGRGVSFQRHFVNAPSCGPSRYTLLTGRYGPAGNNALFMRAADTANVPPSMPEYFRSSG
YTTVSVGKVSHHPGGRGGPDWNDSTIVEMPEAWDRHLMPAAKWKHPRGAMHGLAHGEIRS
DAGGMDVFQAAEGEDDIYPDGVITEEALHQLGLLTAADQPFFLAIGLIKPHLPFGAPQAY
LDRYAGVEFPPIAHPEKPAGRTTWHGSGEFMKYNRWGKNPNEDADFAEEVRRHYAACVSY
ADAQVGKILAGLQRSGADKNTIVVLWGDHGWHLGEHGVWGKHSLFEESLHSPLIVHYPGM
KRAGARADAIVETLDIFPTLCELSGIGVPEFTEGISLRGILEQPEASGHPAVAYTNKAKT
IRTDTHRLTLHDDGFVELYDHTTAGKETVNVAEENPEVVESLRLELRKRLQ
>G0L8Y0|iduronate-2-sulfatase|EC 3.1.6.13|Zobellia galactanivorans (strain DSM 12802 / CCUG 47099 / CIP 106680 / NCIMB 13871 / Dsij)|TrEMBL
MNIRIVALIFLGLLTNCKNNTTPAKEAQAKKPNILFLAIDDLRPELGAYGSDIALTPNID
ALAKDGLRFNNAYCQQAICSPSRASLMTGARPETIQVIENFTYFRDKNPDIATLPQHFKA
NGYETVYTGKIYHGKYNDPELSWSRQPVELNKSEVKFGFKLPENIKMQKENSEAMVAKYG
KNALRNGLGKGPSYEFADFPDNAYEDGFNTDLAIATMKDMLEKNPEKPFFLGMGMKKPHL
DWIAPKKYWDMYDESDIKLAEHDQAPKDGATMGLHASFELRARAGIPKKGDISPEQAIKL
KHAYLACVSYVDAQIGRMLSALDEAGIRDNTIIILWSDHGWHLGDMGIWGKATNYEIATR
VPLIIWTPDMAKENRGKATDALVELVDMYPTLCDLADISKPNTLEGQSFVPLLSNPEQEW
KTAVFSQFPTPALREWAANPLSKGMRETSFGPLIEEVEGRIKTQQGEKWDRDLFENRLMG
YSMRTKNYRFIVWKDYTDKEAEPVFIELYDHNNDPAETVNIAKDRPELVKELMLLFDKGW
EGNRAKVNI
>W8S6E8|iduronate-2-sulfatase|EC 3.1.6.13|Roseibacterium elongatum DSM 19469|TrEMBL
MTFSPDAIADSHICLIWVDDMIDVYTWRDSFGIRIQTPNLDRFMARAARFSNAYATVPLC
APCRAEIATGLSPFRTGLVDLNRFWRDVMRPERAWQYDLRRAGFHTFTTGKVDSNYRPMP
EEYRRILFHEEPEAEDKGRRRGVHAYLDRGPGIKGVNHPDDDGSQDDRFYDFWVAQNAID
FLDRADPTRRNLIQLGFKHPHYNLITPDRFYAQYDPAAIRWPDIAHAEDYFGPQPGFAVY
EAAYIANGVWTPEKAGDEAWRQVVRAYFAAISHVDHEIGRFLDALDASPLGQNTTVIFLS
DNGFNLGNHDSFHKMSQWDSAAHIPLGIWHASMEQGQEIDLPVSLHNIPKTIMHLAGLPP
RPDWTSGQSLLPLIGDGFGSFDETKSPVTSVFGTLSVRPSVEGYRHLRYFRYPNGEEHVY
DIETDPGETENLVATAPMEFLRAELVKGALSLGLDLRGFENPAGGVNAMMAVDGSVILAG
GRGNNDYWAYGSDAEKIHEEKDGGTDTLWYMAGPDDYVLHCPANVEKIRIATVVARHEGD
VAEGKRLQIVAHPHSPIEFETSERVEIDLKGSDGDDIMIGPKHGAATFYGGGGNDLMIAK
AKQANRRHAFYGEAGNDTLHGGPGRDTLDGGTGDDVIHGNTGRNHIHGGHGNDLIHDGEG
ASTIDSGPGRNQLHLGEGDHVIHVGAGLTRIEAGAGAKTFHIAPGGVTVIAGWSPDQRYD
LSRWHARPTITTRGPDQVRLRVGLSILDLHGVAENADIAAQLIQPGD
>A0A840V005|iduronate-2-sulfatase|EC 3.1.6.13|Haloferula luteola|TrEMBL
MKLRTALAACLSLLSVVSAEERKPNVLLILVDDLKPVLGAYGDPVAQTPNLDKFAASGMR
FDKAYCNQAVCAPSRYNYMLGSRSTSTGLYHLNQELRKFVPDAVTLPQYFAKFGYSTQSL
GKTYHVGHGIHGDPQSWTVPPLRDQEVEYALKETTGGQLTREEAYFNNIFDRPINDLPKG
PAWEEADVPDEAYADGRVAAETIKRLEAAAQSDEPFLIAVGFARPHLPFTVPKKYWDLYD
PKKLPMPKTSEFPQDSPPVAHKHGGEIANYKPVPNNGLTDPDLTRQLIHGYYAATSYTDA
QAGKVLDALDRLKLSDNTIVILWGDHGFHLGDHGTWTKHTNYEQANRIPIIIRAPGVTQP
GTSTEQLAQTVDIYPTAAALAGLPAPEGPQPIDGHNLVPVLKDPKARISDHVYHAFPHAV
MGRAIRTDRYRMVEWKRSGAPESTAKYELYDYERDPEETQNLAAKKPKLLEKMKEILHQY
PEAVIR
>A0A8B6DPG6|iduronate-2-sulfatase|EC 3.1.6.13|Mytilus galloprovincialis|TrEMBL
MNIWHGLLFLLVLLTISEGKLNVLLIVADDLRPSLGCYGYEPLITPNIDLLASQSVVFNR
TYAQQAICGPSRASFLTSRRPNTTHVYDQHTYWRKRGGNFTTLPQHFKNNGYVTFSVGKI
FHPGAASGKTDDYPYSWSVPPYHPSTQQYKMAKVCPGPDGKLYMNIVCPVDVIAMPEKTL
PDLQSTQHALQIMQNVSRFPEQPFFLAVGYHKPHIPLKYPREYLNLYPLDKIHLAPDPSL
PPKLPLVAWNPWADLRERDDVKMLNVSFPYGPLPKHYQLLVRQSYYAATSYMDDQVGQLL
KGLDQHNLSSTTVIVFMGDHG
>A0A840CXZ3|iduronate-2-sulfatase|EC 3.1.6.13|Dysgonomonas hofstadii|TrEMBL
MNYRYIIGGSLSLVATSMLAQVKSTDTDTKKMNVLFILADDLRPNLGCYSDPYAITPNID
NIAANGITFGNAYCQQAVSNPSRASMLTGLRPDQTGVTNLYTNFRDSIPDAVTLPQFFKN
NGYCVTGVGKIFHSVAHDIDTISFTKVLPLERRGYLLPQNSRRKGGKQSAYEDADVEDNK
YPDGEIADNAVQMIKNASESSSPFFLAVGFLKPHLPFNAPKKYWDMYKDHKFEIKHRERP
ERSPDIAFHNWDELRGYANMPDTGALNTNQEQELWRGYYACISYVDTQIGKLLDALDEHG
MRDNTIIVLWGDHGYHLGEQDLWCKSTNYELDTRIPLIISVPTGKLKDIYSSSIVEAVDI
YPTLTDYCGFGKSPILAGTSLRSVMDRKDGFKESNYAFSQFVRPYEAILKRTPATHMGYS
VRTPQWRFTCWYNLTTGDIDEKELYLINKDSVESKNLTGDTQYMNVEKELLECVNNYRNE
KY
>F0SJJ9|iduronate-2-sulfatase|EC 3.1.6.13|Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / IAM 15109 / NBRC 103401 / IFAM 1448)|TrEMBL
MKHLFAFAILFGLSAAVDAADKPNILFIAVDDLRPELGCYGSEIAVSPNLDALASDGLLF
NRVYCQQAICRPSRASLMTGARPETTGLFHNYVSLRELQPDIVTLPQHLIGQGYETVYCG
KIFHQGDTDEEHSWSRNPVKWLRGVEKPKGAFALPENNRIKNENFKEMLAKYGDAAKRGL
SSGPAYENADVPDHAYIDGYETLRAIATMKEMAANKDKPFFLALGFKKPHLNWTAPKKYW
DMYDPAEIPMADHDEAPENGAAMGLHASFELRTRSGIPKYGPLGPELSRTLKHAYLACVS
YVDAQIGKMIAAIEEEGLRENTIIVVWGDHGWHLGDMGVWGKATNYEIATRVPLIIWTPD
MQTRGEKTEALVELVDIYPTLCELAGVAVPEHTEGHSFVPLLDKPHQQWKQAAFSQYPNP
ALREWAANPLSAEMRETWFGPLISDVEARIQNQQGDRWNRELFEEHLMGYTMRTDRYRLV
AWRDHRNPDAKPLYVELFDHQTDPQETTNISDDHPELVAELLKQMNAGWKAAL
>A0A7W7YCA7|iduronate-2-sulfatase|EC 3.1.6.13|Prosthecobacter vanneervenii|TrEMBL
MMSRIASLGAMLLLSTLNAPAAACKNVLFIMADDLRPELGCYGAAAITPNLDALARRGVL
FQRAYCQQAVCNPSRSSMLTGLRPGTLGLYVNGTHFRELKPDVETLPGWMKAHGYTTRCV
GKIFHNWHTKEHGDPRAWSAPEFLHYANHGDDTPQVSGPLPPNLATTTGTMHLYGKEPIC
ECRDVPDEAYYDGRVAAEAVRVLGEVKDRPFFLAVGFWKPHAPFNAPKKYWDLYQRDRLP
ALNPARPLAAPEIAFHQSTEVLGPPEKQPVPTREQVAEMRHGYYAGISYMDAQLGKVTAA
LAKHGLLDSTLIVFWGDHGYHIGEHGLWGKTTNFELDARVPLILVPPKARHAGVQTLALV
EMVDLFPTITALCDIPPAPGLDGISLVPLLDNPGSTLKEAAYTQHPRPAYADRTKRGRPE
VMGFSVRTNSLRYTEWRDYDSGRVTATELYDHSRQEAELDNSIATPAAPAALEHARNLLH
RQFPPASQ
>A0A7W7YD40|iduronate-2-sulfatase|EC 3.1.6.13|Prosthecobacter vanneervenii|TrEMBL
MIRAFLFLFVSSASLLAAAKPNVLLICVDDLKPLLGCYGDKVVKTPNIDRLAARGVLFEK
AYCNQAVCSPSRNALLTGLRPQALGIYELATNFRKAAPDAVTLPQHFKANGYHAEALGKI
FHVGHGNVNDVASWSVPHYTPKTISYALKENDLPQSTREQALFENKTEAWKLPRGAATEA
ADVPDNTYGDGMIADEAVKRLEAAKQKQEEPFFLAVGFLKPHLPFVAPKKYWDLYDPASF
KLPALQTAPEGAPEFAPTTWGELRQYMDVPEKGPLTEKQALHLIHGYHAATSYMDAQLGK
LLDALDASGFAQNTIIVLWGDHGWHLGDHGMWCKHTNYEQAGRIPVIVVAPGIQPARTQS
LIESCDIYPTLAELAQLPAPPQGDGRSFASVLRDPKASVRDHAIHVYPRGGGLIGRAIRT
QRHRLLEWKKPGDAPENAVLELYDYEADPAETKNLAAEQPDVVAGLRKLLAQHPEAKPQI
SAKPEAKAAAEKKPVQDRGKMFDQRDKDKDGQLTKEEFLLNQPDPDEAPKRWIKFDTDGS
GTLSREEFIKGGRK
>F7CIX8|iduronate-2-sulfatase|EC 3.1.6.13|Xenopus tropicalis|TrEMBL
MNLFGYLRFLMCATTVFAVWQQPFLPKHTATGGKNVLIIIADDLRTSLGCYGDSAVKSPN
IDHLASQSIIFTNAYAQQAVCAPSRVSFLTGRRPDTTRLFDFNSYWRTHAGNYTTLPQYF
KEHGYVTMSVGKIFHPGISSNHSDDYPYSWSVYPYHPSAEKYENSQTCKGKDGKLHANLV
CPVDVSEVPEGTLPDIQSTEEAIRLLKTVKQQNASFFLAVGYHKPHIPFRFPKEFLKLYP
IENISLAPDPDIPKKLPLVAYNPWTDIRKREDVQALNISFPYGPIPEHFQLLIRQSYYAS
VSYLDDQIGQLLNAVEDLGLSNDTIIVFSSDHGWSLGEHGEWAKYSNFDVTTRVPLIFYV
PGMTNIPQQPIFQYIDPFSTNLQRKFPGKSREYPVELVSLFSTIADLAKLPAPPACPQPS
FHMELCTEGRSLVHQLHASENTHDDAVLAVAYSSYPRPSDFPQWNSDLPDLKDIKIMGYS
MRTMDYRYTVWVGYNSTTFQANFKEIHGRELYFVLSDPNQDNNLYNQLLHLDIYKHFEFM
NN
>A0A7W5H7W4|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula rubra|TrEMBL
MKIIPKLCLLLLFISATSQAADRPNVLFLAIDDLRPELGCYGSEIAITPNLDKLALQGLL
FNRAYCQQAICSPSRASLMTGARPDTIGVVENYAYFRDLNPDIVTLPQHFIANGYEAVYA
GKIFHNDPTADRGTSWSRQPTRPKVKRIQTAGGYALPENQAIWRKNKEILDAKYGRAIAG
NGLIHGPAYEAADVPDNTYEDGYNTDSAIATLKELVADNAKPFFLGLGMKKPHLEFIAPK
RYWDLYDPNDIPLAAHTAPPKNGAAMGLHPSFELRVRDGIPKSGPIDPQMSRTLKHAYLA
CVSYVDAQLGRMIAALEDAGVRDNTIIIVWGDHGWHLGDMGIWGKATNYEIATRVPLMIW
TPDMPEAVRGSKTDALVELVDMYPTFCELAGIAQPDHLEGQSFLPLLQAPHRSWKSAVFS
QFPNPALREWAANPLSAGMRETFFGPLIQEVEGRIIRQQGDKWDRDLFEKHLMGYTMRTD
RYRLVVWQDYRDASADPVDVELYDHQLDPSETINVADAQPELVAELLAQFKAGWKAQLAT
TSN
>A0A7W8DNV5|iduronate-2-sulfatase|EC 3.1.6.13|Prosthecobacter dejongeii|TrEMBL
MFARLLLPTLLFGLFCSAPAPAAEKTRPNVLFIIADDLNTSLGSYGHPLAKTPNLDKLAA
RGVRFEKAACQFPLCGPSRNSMLTGLYPNSNGILANAQVFRQTIPNHQSLSQAFRLSGYF
AARIGKLYHYNVPLSIGTNGHDDPGSWEMEINPAGADRMEDMDHTFSLIPGNYGGTLSWY
ASPNPDEKHTDGLMAREAAWVLERCAKDKSRPFFLALGFFRPHTPYIAPKAWFEGYPVDQ
MPVVQGVKEDQADLPKHALGSYKKEQDKLTDDLRRQAVQAYLASISFMDAQAGVVLDTLD
RLGLSENTIVVFTSDHGYHLGEHGLWQKQSLFEESARVPLIMAGPGVTPGAVAQAPVGLI
DLYPTLTELCGVKAPANLQGQSLVPMLKDPKAEGRGWVISQVVRGGGFKRMGASAAAGDN
GKRIFGYSLRTPRWRYTEWAEGKEGRELYDHDTDPKELTNLAEKPDHAATVTELSTQLAG
IVKSTFPADGVTPTVKETGMWAPNLTDP
>G0L7B4|iduronate-2-sulfatase|EC 3.1.6.13|Zobellia galactanivorans (strain DSM 12802 / CCUG 47099 / CIP 106680 / NCIMB 13871 / Dsij)|TrEMBL
MSLSKFIGILFLLGQAVGCSSAQNSIPKKESKKPNILFIAIDDLRPELGSYGSEIARSPN
LDKLASEGLQFNRAYCQQAICGPSRASVLTGLRPETSGIFHNYLKIRELHPDIVTLPQHF
KNNGYESVYYGKIFHHGDLDDSLSWSRVPGPQPKSVVGFALPENQQLREETRKEMFSKYG
DVAKYGLAMGPAYESAKVPDNTYADGYNTDLAIADIKKMAKKSDQPFFLGLGFHKPHLNW
VAPKKYWDLYDESKIPMASDSTPPKDGAAMGLHPSFELRVRSGIPKTGKLPPELARTLKH
AYLACISYVDAQIGRAIQALEEAGIRDNTIIIVWSDHGWHLGDMGIWGKATNYEIATRVP
LMIWTPDMPDSNRGVQTEALVELIDMYPTLCELAGIEKPVHLEGQSFAPLLKHPEQDWKT
AVFSQFPSPALREWGSYPLRPAMRETYFGPLLEEVELKIKAQQKEKWDRNLFENKIMGYA
MRTDQYRFIVWKDRTLTQASPLYFELYDHKKDPGETVNIASSNPQLVARLMAQFKKEKEQ
HSLN
>Q7UTP7|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)|TrEMBL
MRPWMLLPILCAISVPVAAKESMNVLFIISDDLTSTALSCYGNDVCQTPNIDALAAEGMR
FTRAYCQATYCGPSRASFLSGYYPHATGVLGYKSPRPQIGDRQTWPQAFKDAGYYTARVS
KIYHMGVPGGIETGGDGADDPLSWVERFNSPGPEWKAAGVGETLEGNPDGSRPVVGGNTF
VVVEAEGGDEVHSDGKTAAKASDLIREKREQPFWLGVGFVRPHVPFVSPAHYFEPFKPFS
KLSLPERVEGDWNDIPKLGINYKTSMNMKMDLRRQRKAIGGYYASVAYMDAQVGKVMTAL
RESGKADNTIVVFTSDHGYHLGEHDFWAKVSLRDESSQVPLIIKVPGKAPGVCNSLVEML
DLYPTIGNLCGINVPEHVQGTDISKMLDDPNHTVHEFAFSVAPMRKGFLIRTDRWAYIQY
KEDASGGMELFDMESDPKQFTNLATSAEHQSIVAAMKLILKSKLAELRANDLAESVD
>M5RND9|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula maiorica SM1|TrEMBL
MPFAVSIAVLLACCSAFADNAADVSDGDRSASMPNVLFIAVDDLRPELGCYGSEIAITPN
LDALASDGLLFNRAYCQEAICSPSRASLMTGARPDTIGVVENNAKFRDLNPDIITLSQHF
IANGYEAVHCGKIFHSPAHADMANSWSRSPSKKNLKLKAPSGTYALPENQAIQKRNLETL
QAKYGEGIRGTGLVHGPAYECADVPDQAYRDGYNTDLAIATMKELAGSDQPFFLGLGFFK
PHLEFIAPKRYWDLYDPAAIPLATQDKAPVDGAAMGLHASFELRVRDGIPKTGAIDPELA
RTLRHAYLACVSYVDAQVGRMITALDDAGLRENTIIIVWGDHGWHLGDMGVWGKATNYEI
ATRVPLMIWTPDMPAGTRGKTTEALVELVDMYPTLCDLAGISKPSHLEGTSFQPLLKNPN
REWKSAAFSQFPNPALREWAANPLQPSMRETFFGPLIQEVEQRIISQQGEKWDRELFENR
LMGYTMRTDRYRLVVWKDTENPQAAPIDIELYDHQNDPNETVNIADRSPDVLTKLLAQFD
KGWQGQRPQGRPKNDGQKDSQTD
>G0LCF0|iduronate-2-sulfatase|EC 3.1.6.13|Zobellia galactanivorans (strain DSM 12802 / CCUG 47099 / CIP 106680 / NCIMB 13871 / Dsij)|TrEMBL
MFRYFTALYLVLGLSNHLSAQTQDRPNVLFICVDDLRTELGAYGKHYVKSPHIDALAKTG
ALFTNHYVQVPTCGASRHAILTGMRPSKPIHLSNNSIVEEISGQPEKETPETFIHRFKQD
GYHTVGIGKISHSADGLVYGYEAQPSEQRELPHSWSELLFNPGKWKTGWNSFFAYANGEN
RQSLKKQVKPYEAGETDDQGYPDGLTADLAISKLKELKKKGQPFFMGVGFFKPHLPFNAP
KKYWDLYDENKIPLSPNPDIPENVNLKSLHGSGEFNQYALGEEKAGLDTQVSDAYARKLR
HGYLASISYIDAQIGKLYQELKALELDKNTIIVIWGDHGWHLGDQRVWGKHTLFENALKS
TLIINSPLPQHKAKKVRAIVESVDIYPTLLDMCGIDQIKPTDGESFEKHIKYNIPDTEEV
AYSYFRNGISMRTKDYRLTKYFRKDQPVIELYDHHKGNAIENKNIADKKPNTVKELMPLL
NKGDTGLYNASE
>F4C4H3|iduronate-2-sulfatase|EC 3.1.6.13|Sphingobacterium sp. (strain 21)|TrEMBL
MIKKKTWSLFILLLCIAVCPLSGQDINENSKQKRPNILFILVDDLKPALGTYGDPVAITP
NMDRLATKGMRFDMAYANQAVCAPSRFNLMLGSRSSSSGIYGFGQNFRDYYPNATTLPQF
FKGQGYHTESMGKVFHIGHGTYNDEQSWSVPHHKDLVIEYVDPASKQEGFTREEALFSNQ
SAKGLPRGVAWESPEVADDAYADGRTAARAVKRLKELSENKQDDQPFFLAVGFARPHLPF
SVPKKYWDLYQKENLPLPTYEKAPEDAPSYAVKRDTEIDQYKPVRPSSEQDPFPLELKQQ
LIHGYYAGVSYVDAQIGKVLQALEDSGLDENTIVVLWGDHGYHLGEMGIWTKHVNYERAN
KIPLLIVAPGVSQPATATSALVETVDIYPTLVELAGFPQPRVEQPFDGVSLVPLFRNPKA
KIGDHAYHCFPRGGRLGRAIRTDRYRLVEWKKIGEPVESAEYELYDYQYSDVEMKNIAKD
EPSILEEMKKILASHPEAVPSKP
>A0A7W9SNB0|iduronate-2-sulfatase|EC 3.1.6.13|Armatimonas rosea|TrEMBL
MKLLLSLVSLVALATLTAPALAQSKPNVLFIAVDDLRPELGCYGNTVIKSPNIDRLAKSG
MVFQQAYCQQAVCSPSRSSLLTGRRPDATKVWDLVTHFRTALPDTVTLPQYFKQQGYHAA
GLGKIYHGGYDDAPSWSVPHWTPKTKELDTTKSHAYLATDKAEEQLPDGAVAAEAISRLK
DYKKSGQPFFLAVGFVKPHLPFVSPKKYWDLYDPAKIPGGDSDTLPEGAPAFVGHDNGEL
HGYGNIPAGNPISPAVSRELRHGYYAAISYMDAQVGKLLDTLKAEGLDKNTIIVLWGDHG
WQLGDHGLWHKHTNFERATHAPLIVSAPGMPNAGKTTPALAEFVDIYPTLAELAGLPQPT
GLDGKSLKPILDNPSASVRKVALSQYPRSADGKPVMGYSARDTRWRLTLWRDRTSGATVA
TELYDEKNDPKESVNVAAKPENAAVIAELTRELDTAYANLGAPVPTTKNAKTPQKAATDR
VALFNRKDTNKDDQLTYDEFMAGQPDPEQAKERFKKFDTNKDGKLSRDEFIKQGK
>A0A7W5DUI2|iduronate-2-sulfatase|EC 3.1.6.13|Rhodopirellula rubra|TrEMBL
MLLLRLEGARWQFSFLFIGMLGLSIGDAVSADGADSTRPNVLFLVVDDLNDWVGCLGGNR
DARTPNIDQFAEQSVLFRNAHCQVALCNASRTSVLTGMYASTTGIFANSLKHAGPVYQSA
TQMPVWFREHGYRTMCMGKIYHNDHGKKAYWDEVGPKTLRWGPEPPEGRQFTKRFGDRVQ
DSLAWAALDIERGEMPDEQIATWAKTKLEEEHQQPFFLALGFYKPHTPMTAPKRYFDLFD
REKLAMPEVLENDLDDVPEIGKRWVLDRSDLIADDAVDQYSPTYRRELVHAYHACVALTD
DCIGQVLSHLKNSEYADNTIVVLFSDHGWHLGEKHHWRKWMPWEESTRSLMALHAPGVSR
DGSVCDRTVGLIDIYPTLAELCGLDPPAQLEGESFVRLLVDPKDEWTRPALTSTKAGNHT
VRSDRWRYIRYRDGSEELYDHEKDPHEWHNLANQPELQPVKEQHAHWIDVLTEGEIIE
>F0STA5|iduronate-2-sulfatase|EC 3.1.6.13|Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / IAM 15109 / NBRC 103401 / IFAM 1448)|TrEMBL
MRFHLWLLAIVFLAAEPIVAADAPNVLLICVDDLRPELASFGAEHMHTPNIDALAARGRA
FTRHYVQAPTCGASRYALLTGLYGPAGNHALFERAKKLKANPDQVPPSMPEWFRANGYET
VSVGKVSHHPGGRGGANWDNDQEPEMPNSWDVHLLPAGDWQHPRGAMHGLAHGEIRGNAK
EMDVYQSAKGPDEIYPDGLIVNESLSQLQRLSTSGNPFFMAVGIIRPHLPFGAPAKYFEP
YREVVIPEIPHPQKPGGKTTWHGSGEFMKYNRWGRNPNEDAEFADLVRRHYMACVTYADA
QVGRLLKELNELDETEHTIVVLWGDHGWHLGEHAVWGKHTLFEESLRSPLIICADGMPEP
GVSTDAIVETIDVFPTLVDLAGLPQPEYVAGQSLKPLLEDPTADGGTAVSYAPKGETIRT
DRYRLIEHRGGHVELYDHDSEAGETKSVAEDHPAVVKELKDELKTRLGR
>F0SKE6|iduronate-2-sulfatase|EC 3.1.6.13|Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / IAM 15109 / NBRC 103401 / IFAM 1448)|TrEMBL
MTTTLRGICCGAAALLLSLVAGSANAAERPNVLFLICDDLNCDLACYGHDQVQSPNIDRL
AEQGVLFERTYCQYPLCGPSRASFMTGLYPQQTNITRNSIYLRDRLPDVTSMSQLFSQNG
YTASRVGKIYHYNVPKDIGTPGHDDPQSWTRTFNPRGRDKDEEDLVFSLRKGSYGGTLSW
HAADGTDAEQTDGIAAAEAVKQLNEYAKSEEPFFMAVGLYRPHTPYVAPKKYFDLYPLDT
IRVPQIRAGYLDSLPKPAQTSVTRKKEQVNLEESLAKQAIQAYYASITFADAQLGQILDA
LDDSGLADNTIVLFTSDHGYHMGEHGHYQKTTLFENALRVPLIISSPGMKAAGGRVSTPV
EMVDFYPTLAQLAGLDAPEYVAGVSLADALDDSTSRPREDALSEYANGYSLRTDRFRYTS
WGREGQLGVELYDHQTDPAEMNNLAGDAEHADVQKRLAKRLEQRIAASNKQPAELTRLTP
GQKKQKK
>A0ST40|iduronate-2-sulfatase|EC 3.1.6.13|Danio rerio|TrEMBL
MNVMLVFTCWWFVLIFHLLGRDVFAAKSKDFNVLYLIADDLRPTLGCYSDPVVKSPNIDQ
LASLSVVFHNAYAQQAVCGPSRVSFLTSRRPDTTKLYDFNSYWRVHAGNYTTLPQYFKSN
GYTTLSVGKVFHPGIASNHSDDYPYSWSVPPYHPPSFEYEKRKVCKDKDGTLHSNLLCPV
NVSEMPLGTLPDIENTEEAIRLLRSMKGSQKPFFLAVGFYKPHIPFRIPQEYLKLYPIEN
MTLAPDPDVPKKLPDVAYNPWTDIRKREDVQALNLSFPYGPIPKDFQLRIRQHYFASVSY
VDAQVGKILQTLDDVGLAKNTIVVLSSDHGWSLGEHGEWAKYSNFDVATRVPLMVYKAGV
SSRRSRTGAKTFPFIDVFQDTREHFGKGKIVNSVVELLDVFPTLANLAGLPSVHHCPSPS
FKMDLCTEGSNLANLIRNPKHLNREAYSFSQYPRPSDSIQENSDLPNLADIRIMGYSIRS
NDYRYTLWVGFDPLHCKPNMTEIHAGELYILTEDPGQDNNLFDEFGHAALLNKFGTMPSW
TESLKQHMMYFSSGLKSKGLS