>Q9VJ79|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila melanogaster|Swiss-Prot
MGQAASMCRFRGCRYKNKNKSSKQQQQQQQQQQQQQQQHQQQQQQTPSHSPQIQHHSEII
PATTGLHLRSIEEPATTPLQFQPTGRMNTEQGGTGYGGYGSSEHSLLIATRHAGVPLPLA
QHQPLPAHYQPLNHSGAAPPSSSNGSSSSGGGVQTSATPQQQQQYQVQQPYQYQYQHHYH
HQANSPQHHRPYDPEHARMEAWLDENQEFVQDYFIRKATRQTVDAWLVSHATSAGNDVVS
STSPTHANGQTSSSRGGSGATTPVRKISAHEFERGGLLKPIVNTIDGTPTFLSIGPPMDN
GSVGGSCSNLQNVGGVVAGQYQYNHQQHHHNHAHLHHSQHSHYQAGGAVGSSSLGSTGGA
SGAGGAPSLGGSGGAGNGHQYPYYHCHQRPQRLSRNELKQLDEKELIFELVKDICNELEV
RTLCHKILQNVSILLNADRGSLFLVQGRCNGPDGLKKCLVSKLFDVCPRSTVEEMEQQDE
VRVAWGTGIAGHVAESGEPVNIPDAYQDERFNCEIDSLTGYRTKALLCMPIKDSSGDVIG
VAQVINKMNGECFSEIDEKVFSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLDLARMIFE
EQSTIEHMVFRILTHMQSLIQCQRVQILLVHEADKGSFSRVFDFEANDLSEEEATSRTSP
YESRFPINIGITGHVATTGETVNVPNAYEDDRFDASVDENSCFKHRSILCMAIKNSLGQI
IGVIQLINKFNELDFTKNDENFVEAFAIFCGMGIHNTHMYEKAIVAMAKQSVTLEVLSYH
ASATMDEAHRLRRLRVPSAVHFRLHDFKFDDIHFEDDDTLKACLRMFLDLDFVERFHIDY
EVLCRWLLSVKKNYRNVTYHNWRHAFNVAQMMFAILTTTQWWKIFGEIECLALIIGCLCH
DLDHRGTNNSFQIKASSPLAQLYSTSTMEHHHFDQCLMILNSPGNQILANLSSDDYCRVI
RVLEDAILSTDLAVYFKKRGPFLESVSQPTSYWVAEEPRALLRAMSMTVCDLSAITKPWE
IEKRVADLVSSEFFEQGDMEKQELNITPIDIMNREKEDELPMMQVNFIDSICLPIYEAFA
TLSDKLEPLVEGVRDNRGHWIDLADVVKTKTSQDQEPEEEQQQQNVISNGDCKAMSDDDV
AASEAEVAVDSPSEKASVNGSNVANNSSNTNKKIAVASHPTSTQPSDDDNDVDADADDVD
EQAAEENGHDAEVDEASCRSNSTCSSSTASSCLSTPPPTGEDDSTPVSPLKTLQAKLVAA
NLNALQRQTSNQAQTQKQRCKSCDHSRSGLQVRKTSSLRGAQELDLDSKTRNGTHAALCK
STPVINNHSHHHNHSHSHNHNHHHHHHHHSHHNHSQHGIGIGSASIGGSGLISLTTPLLA
MDSDRIPKIVGKIGNLDGLPFANGIGGPQNGHGLPFGSYQHHHHHQHHHHLLARRHSETN
SNGATAMAVEK
>Q9HCR9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|Swiss-Prot
MAASRLDFGEVETFLDRHPELFEDYLMRKGKQEMVEKWLQRHSQGQGALGPRPSLAGTSS
LAHSTCRGGSSVGGGTGPNGSAHSQPLPGGGDCGGVPLSPSWAGGSRGDGNLQRRASQKE
LRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRV
NLPRYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSL
FLVEGAAAGKKTLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIP
DAYQDRRFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQ
MYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKC
ERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESMEKSSYSDWLINNSIAELVA
STGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFD
DADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANI
PLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRM
VLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSG
SALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLY
FERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFE
QGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVAT
NRSKWEELHQKRLLASTASSSPASVMVAKEDRN
>Q13946|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|Swiss-Prot
MEVCYQLPVLPLDRPVPQHVLSRRGAISFSSSSALFGCPNPRQLSQRRGAISYDSSDQTA
LYIRMLGDVRVRSRAGFESERRGSHPYIDFRIFHSQSEIEVSVSARNIRRLLSFQRYLRS
SRFFRGTAVSNSLNILDDDYNGQAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSL
HGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPW
DILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFS
HLPLESRQQMETQIGALILATDISRQNEYLSLFRSHLDRGDLCLEDTRHRHLVLQMALKC
ADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRHTESIANIQIGFMTYL
VEPLFTEWARFSNTRLSQTMLGHVGLNKASWKGLQREQSSSEDTDAAFELNSQLLPQENR
LS
>P70453|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus musculus|Swiss-Prot
MGITLIWCLALVLIKWITSKRRGAISYDSSDQTALYIRMLGDVRVRSRAGFETERRGSHP
YIDFRIFHSQSDIEASVSARNIRRLLSFQRYLRSSRVFRGATVCSSLDILDEDYNGQAKC
MLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMVKLRRFLVMIQEDYH
SQNPYHNAVHAADVTQAMHCYLKEPKLASSVTPWDILLSLIAAATHDLDHPGVNQPFLIK
TNHYLATLYKNSSVLENHHWRSAVGLLRESGLFSHLPLESRQEMEAQIGALILATDISRQ
NEYLSLFRSHLDKGDLHLDDGRHRHLVLQMALKCADICNPCRNWELSKQWSEKVTEEFFH
QGDIEKKYHLGVSPLCDRQTESIANIQIGFMTYLVEPLFTEWARFSDTRLSQTMLGHVGL
NKASWKGLQRQQPSSEDANAAFELNSQLLTQENRLS
>O08593|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rattus norvegicus|Swiss-Prot
DQTALYIRMLGDVRVRSRAGFETERRGSHPYIDFRIFHAQSEIEASVSARNIRRLLSFQR
YLRSSRFFRGATVCRSLNILDEDYNGQAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFH
LFSLHGLIEYFHLDMVKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANS
VTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRES
GLFSHLPLESRHEMEAQIGALILATDISRQNEYLSLFRSHLDKGDLHLDDGRHRHLVLQM
ALKCADICNPCRNWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRQTESIANIQIGF
MTYLQEPLFTEWARFSDTRLSQTMLGHVGLNKASWKGLQRQQPSSEDASAAFELNSQLLT
QENRLS
>Q9NP56|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|Swiss-Prot
MSCLMVERCGEILFENPDQNAKCVCMLGDIRLRGQTGVRAERRGSYPFIDFRLLNSTTYS
GEIGTKKKVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGMWDFDIF
LFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAAD
VTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMS
VLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHN
KDLRLEDAQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEIS
PLCNQQKDSIPSIQIGFMSYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLLPRQ
HRSRGSSGSGPDHDHAGQGTESEEQEGDSP
>Q9QXQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus musculus|Swiss-Prot
MSCLMVERCGEVLFESPEQSVKCVCMLGDVRLRGQTGVPAERRGSYPFIDFRLLNNTTHS
GEIGTKKKVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGTWDFDIF
LFDRLTNGNSLVTLLCHLFNSHGLIHHFKLDMVTLHRFLVMVQEDYHGHNPYHNAVHAAD
VTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMS
VLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHN
KDLRLENVQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEIS
PLCNQQKDSIPSIQIGFMTYIVEPLFREWARFTGNSTLSENMLSHLAHNKAQWKSLLSNQ
HRRRGSGQDLAGPAPETLEQTEGATP
>Q54HY0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dictyostelium discoideum|Swiss-Prot
MKYLILILIFFIEINNGSRLINSGNLFSELKDYYIPENLNYYSGGYSEQHCKDSSYITIP
LGVTGGLDEGSLSSFLLTKKGSSLFIGLDAGTVWQGVRRLTMLQDFNSVFNITYPPWATL
PEQRATWFIKNHIQGYLIGHSHLDHVGGLIVESAEDQLSPKKNELEVSQPEIYRGCIEMI
HKMGYVSDFPNITSIPDQKKPIIGINETLYSMATDLFNGFVWPSLPNYGRYSYYYLGNGN
QYSFKDLTPYANKYVTKVQNDFPFNHLVKSFEICHDSLTSTAFILTDSQSGEQIVFFSDT
GISTTKCDWEFKILQVWRNIKIDKLKAVYIESSFTNEVADNVLFGHLRPKDIMKLMDSLL
ENSIQTSPPKTNLKHVKLIIEHIKPQVGMNQYYLTSQRMVYQQLQEINNHGVKVIIPNQG
VPICL
>O60658|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|Swiss-Prot
MGCAPSIHISERLVAEDAPSPAAPPLSSGGPRLPQGQKTAALPRTRGAGLLESELRDGSG
KKVAVADVQFGPMRFHQDQLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTKEAQAVLACF
LDKHHDIIIIDHRNPRQLDAEALCRSIRSSKLSENTVIVGVVRRVDREELSVMPFISAGF
TRRYVENPNIMACYNELLQLEFGEVRSQLKLRACNSVFTALENSEDAIEITSEDRFIQYA
NPAFETTMGYQSGELIGKELGEVPINEKKADLLDTINSCIRIGKEWQGIYYAKKKNGDNI
QQNVKIIPVIGQGGKIRHYVSIIRVCNGNNKAEKISECVQSDTHTDNQTGKHKDRRKGSL
DVKAVASRATEVSSQRRHSSMARIHSMTIEAPITKVINIINAAQESSPMPVTEALDRVLE
ILRTTELYSPQFGAKDDDPHANDLVGGLMSDGLRRLSGNEYVLSTKNTQMVSSNIITPIS
LDDVPPRIARAMENEEYWDFDIFELEAATHNRPLIYLGLKMFARFGICEFLHCSESTLRS
WLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIHDVDH
PGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQG
IIDMVLATEMTKHFEHVNKFVNSINKPLATLEENGETDKNQEVINTMLRTPENRTLIKRM
LIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQGLPVVMPVFDRNTCSIPKSQIS
FIDYFITDMFDAWDAFVDLPDLMQHLDNNFKYWKGLDEMKLRNLRPPPE
>O88502|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus musculus|Swiss-Prot
MGCAPSIHTSENRTFSHSDGEDEDVDVDVPGPAPRSIQRWSTAPGLVEPQPRDNGASKVS
VADVQFGPMRFHQDQLQVLLVFTKEDSQCNGFHRACEKAGFKCTVTKEVQTVLTCFQDKL
HDIIIIDHRYPRQMDAETLCRSIRSSKFSENTVIVGVVRRVDKEESSLMPFLAAGFTRRF
IENPNVMACYNELLQLACGEVRSQLKLRACNSVFTALEKSQEAIEITSEDHIIQYANPAF
ESTMGYQSGELIGKELAQVPINEKKGDLLDAINSCVTVDKEWQGVYHTQKKNGDNIQQNV
KIIPVIGQGGKIRHYVSIIRVCNGNNKVETTTECVQTDSQTDNQAGKHKDRRKHSMDAKA
VSSRTSDVSSQRRHSSLARIHSMMIEAPITKVINIINAAQENSPVPVTEALNRVLDILRT
TELYSPQFNAQDDPHATDLVGGLMSDGLRRFSGNEYILATKNLPPLSNNLATPVSLHDVP
PRIALAIENEEQWDFDIFELEVATQNRPLIYLGLKTFARFGMCEFLQCSETTLRSWFQMI
ESNYHSSNPYHNSTHAADVLHATAYFLSRDKIKETLDRIDEVAALIAATVHDVDHPGRTN
SFLCNAGNQLAVLYNDTAVLESHHVALAFQLTLENDQCNIFKQMERNDYRTLRQSIIDMV
LATEMTKHFEHVNKFINSINKPLTAQESEEPDRSLEDIKAMLKTPESRALIKRMMIKCAD
VSNPCRPLEHCIEWAARISEEYFSQTDEEKQLDLPVVMPVFDRNTCSIPKSQISFIDYFI
TDMFDAWDAFVDLPNLMQHLDDNFRYWKGLDEKKLRSLRPPPE
>O95263|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|Swiss-Prot
MGCAPSIHVSQSGVIYCRDSDESSSPRQTTSVSQGPAAPLPGLFVQTDAADAIPPSRASG
PPSVARVRRARTELGSGSSAGSAAPAATTSRGRRRHCCSSAEAETQTCYTSVKQVSSAEV
RIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEII
VIDHRQTQNFDAEAVCRSIRATNPSEHTVILAVVSRVSDDHEEASVLPLLHAGFNRRFME
NSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFER
MMGYHKGELLGKELADLPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVK
ITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHKIHRDSGDNSQTEPHSFRYKNRRKESIDV
KSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLE
ILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPITI
NDVPPCISQLLDNEESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAW
FQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP
GRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAI
IDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIKRMMIKCA
DVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYF
ITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS
>E9Q4S1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus musculus|Swiss-Prot
MGCAPSIHVSQSGVIYCRDSDESNSPRQTSSVSQGPTAPLHGLFVQTDAADAMPPSRAAG
PPGAVRVRRSRAELGSGSSTGSSGPATTTCRGRRRHCCSSAEAETQTSYTSVKVLLIFAK
EDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEIIVIDHRQSRNFDAEAVCRSIR
ATNPSEHTVILAVVSQASDDHEEASVLPLLHAGFNRRFMENSSIIACYNELIQIEHGEVR
SQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFERMMGYHKGELLGKELADLPKS
DKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVKITPVIGQGGKIRHFVSLKKL
CCTTDSNKQIHRIHRDSGDNSQTEPHSFRHKSRRKESIDVKSISSRGSDAPSLQNRRYPS
MARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLEILRTTELYSPQLGTKDEDPH
TSDLVGGLMTDGLRRLSGNEYVFTKNVHHSHSHLSMPITINDVPPSIAQLLDNEESWDFN
IFELEAVTHKRPLVYLGLKVFSRFGVCEFLNCTETTLRAWLQVIEANYHSSNAYHNSTHA
ADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHPGRTNSFLCNAGSELAVLYND
TAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAIIDMVLATEMTKHFEHVNKFV
NSINKPLAAESEGSDCECNPTGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRIS
EEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPALMQH
LADNYKHWKTLDDLKCKTLRLPSDS
>Q6NNF2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila melanogaster|Swiss-Prot
MGCSPSTLPPAPSAGQTGERGSLPLDASEKDESRLFCIKLRRSRLRRCSCGGVTLQPPSD
GNGSTAGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHSVVRRATGSTG
TSGTSSSGGNSRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLVFH
KSDSICEAITAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSSKNLDAEH
IARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQIL
HSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLE
DIFVSDLSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVP
GGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKII
NLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYS
SRRSSNDSIIRTGSSTRTAAIVPAKMKSNPIIMELLDESLSWDFDIFKLEEITDYHPLLY
LGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLT
NKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITF
KLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPRDHNP
QTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMF
DRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLAEI
MAKQPPVGKMANSK
>Q8I6Z7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Plasmodium falciparum (isolate 3D7)|Swiss-Prot
MGKVEDFEEHNKNSNQDIEKNVGNRRRSNSNTINDQNENINKNKAIVTKKSFIMNLLRNK
EKTKVEQNDDNIVENMNERKNSLKDMSLISDNVEKDNKVKKKNSYLKNLNILGKTKSIEF
SFPSNILNNARKNIQEIDEESPLTSNSLRTYKEGISEDNRQNQRNADNNSLNWSTSNINT
ECNSEFSNIEVKVLKTEKSNSVKLKDNIIDIPNDKNKKELQEINIKNTNKDSYKNLYLKV
RNSISFNDNIKIDDENKNDKNNIIDNYNNYDDINSSNEITIDGLNHDDNIKKIDNINNFD
NKHDDNLQDHHQNHVHHTFRSSRKSLGNIKSNNTNIKLNNDKNFDTNINKRSILEKYFYD
IWKRNITIKKEIYSLSSKNPPNPLKSTFADACQNESSEKELLKKIPLKFNDDSIESLYVL
NLNNWISSRMIIIGIVMLILSFIIWPLTTWSLKTSTWGRETYIIILFHTLMAINTLILIF
FIIIGSTELCKYSECMSYVLFSLMVALWGLWNIAIGLTLEYNPNLSEMPTTTYELEMIYV
LTYIYGFLPLVIIDIFFPSRTKYNWIIHLIFIFLNSSSIILVGSAKPDFVPEIYVVFRIL
AYTTLCIFLYIGSYTSELQIRYVFYNLLVAGYKLDKIESDMKNKTSNKKISTGIEDLINM
LKECTKVILELENETDTNFNVHTKTSYCSNILEQCLSTLTKSDNLYNIDYNVLENPENKK
FIEAYVSKSKSNFAGEEVPKGVDFKLNKSFSNNDCISTDKVDLDKKQIKKFLKQINISQL
TKMIQFIDNKLLSDWDFNCLTYFDESEYPFFDINLSLICTIDHNIPINIIINFLCFVEKQ
YNNVPYHNTIHATMVTQKFFCLAKKLGIYDDLEYKIKLVMFISGICHDIGHPGYNNLFFV
NSLHPLSIIYNDISVLENYHASITFKILQLNQCNILKNFSEKDFRMMRSYIIELILSTDM
KHHFEIISKFRIRRENEDFDYIKNSDDLLILTKMIIKSADISHGSVSWSEHYCWCQRVLS
EFYTQGDEELKNKMPLSPLCDRTKHNEVCKSQITFLKFVVMPLFEELSHIDNNKFIKSFC
LKRLNSNCIMWDTLMKEEKTIEVYDPAAVKLKDKKKKKVDKKKKSYIDLTLFFIKNVSD
>P12019|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dictyostelium discoideum|Swiss-Prot
MALNKKLISLLLLIFIILNIVNSHQQEDCDDDDEDIGISAERSERRSVKNSNDGSNFYNL
NDYYTPENWNYYSGSFATKDCRDASYITIPLGTTGGLDEGNLSSFLLTKKGSNLFIALDA
GTVWQGVRRLTTFKYFNTLFNITYPSWAVLPEQRTSWFLKNHVMSYFIGHSHLDHVGGLI
LVSPEDYLAKNWIDVQPPINNGIMGLIRKLGFKPTDFTSSSILQKKTIMGLPSTINSIST
NLFNNQVWPNLPSFGRYQYFSLASGIEYPFTELVPYNATTMSLVANEFPFSVKVKPFELC
HDNLISTSFLFTDSISGEQIAFFSDTGVPSSVACDWEGKIYAVWKQIKIDKLKAIYIETS
FPNNTPDSAMFGHLRPRDVMKLMDQLLVQSIQTSPPMTNLKHVKLIIEHIKPQVAEDPNG
WTTQRVIYQQLKEANNNGVRIIIPNQGDPICI
>Q23917|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dictyostelium discoideum|Swiss-Prot
MNNKQEEIDQFLSSTSTSPSPSSSSSPSNNDSTSLKSMISGIENLNVHSKGNDNKNNNNN
NNNNNSNNNEKQKDIVSLENNSSSNNTTTTTTTTTTSNHNSNNNSNNNNNNINNNNINNN
NYEPLVNGHNNGFGDKLNDQPSPSSHRVSDFSDEYSPSKVRILVADDDDVQRKILNNLLK
KFHYNVTLVPNGEIAWEYINKGQQKYDLVLTDVMMPHITGFDLLQRINDHPVHRHIPVIL
MSGTAVDYKYANDTIKIGGQDFLTKPIAKELLKKKIDTVLQSIWQRRKEEEYKATLAQER
EKGNKLAKEMELKEHEIEELTKKVSKMSSISKEAMESPLVSVTRNIEELLKQSSWSHYES
EIKEKLSSILKELGSSNIYRPSFEKLIKNDSVDPVTKSFLVSEFSSTTSRRNSIPTFPQT
TYNRDTKEVIKGWEFDVFKYSEDDLMPLLVDMFENFQLPEIFKIPIEKLQRFIMTVNALY
RKNNRYHNFTHAFDVTQTVYTFLTSFNAAQYLTHLDIFALLISCMCHDLNHPGFNNTFQV
NAQTELSLEYNDISVLENHHAMLTFKILRNSECNILEGLNEDQYKELRRSVVQLILATDM
QNHFEHTNKFQHHLNNLPFDRNKKEDRQMILNFLIKCGDISNIARPWHLNFEWSLRVSDE
FFQQSHYETICGYPVTPFMDKTKTTRARIAADFIDFVASPLFQSMAKFLKESQFLLKVIS
KNRENWQAYMELQKEGKCNDDDLQFMEDPTILVKSKLPKIDEEENRDKVSSSSSSSTAPL
TSTSSSNNETSSS
>P06776|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)|Swiss-Prot
MSTLFLIGIHEIEKSQTIVQNEHYFDRVIELQDLDSLMVALYKDRVSPFPNVHNFETGVS
IVLYDPSKFQLSVRQLDVLFKRFFPSFNISAIDHTREENLQRLECVERENSICRNRITRI
NHWMYHHHDDTPDGINKNSYGTVNGNSVPTQACEANIYTLLLHLNDSKAQHLRKASVPRL
IRNIEFMSFLSDPIEKISQEGSHYWNILSTWDFCALSLSTQELIWCGFTLIKKLSKDAKV
LIADNKLLLLLFTLESSYHQVNKFHNFRHAIDVMQATWRLCTYLLKDNPVQTLLLCMAAI
GHDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHRELFQQLLSEHWPQLLSISKKKFDF
ISEAILATDMALHSQYEDRLMHENPMKQITLISLIIKAADISNVTRTLSISARWAYLITL
EFNDCALLETFHKAHRPEQDCFGDSYKNVDSPKEDLESIQNILVNVTDPDDIIKDHPHIP
NGQIFFINTFAEVFFNALSQKFSGLKFLSDNVKINKEYWMKHKKPQ
>P0AEW4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli (strain K12)|Swiss-Prot
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>P44685|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)|Swiss-Prot
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNEFDVILA
TGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLGKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAEFFPNMQEEGY
>Q8DEI1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio vulnificus (strain CMCP6)|Swiss-Prot
MQHTSSDTLSENSIKLLQITDTHLFASDEGSLLSVKTLQSFQAVVEQVMARHVEFDYLLA
TGDISQDHSAASYQRFADGIAPLEKACFWLPGNHDYKPNMSSVLPSPQITTPEQVELNAH
WQLILLDSQVVGVPHGRLSDQQLLMLEHHLQASPEKNTLILLHHHPLLVGSAWLDQHTLK
DAEAFWQIVERFPMVKGIVCGHVHQDMNVMHKGIRVMATPSTCVQFKPKSDDFALDTVSP
GWRELTLHANGEITTQVQRLASGSFLPDFTSSGY
>O89085|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cavia porcellus|Swiss-Prot
PWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKDREPQE
APRQRPCQQLPPPVPHLQPMSQITGVKRLSHNSGLNNASIPRFGVKTDQEELLAQEL
>Q9W4T4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila melanogaster|Swiss-Prot
MMRLARFTQGFSFNKNVAKHRGSGSSNGTGNGSGTGNGQGLGGSCSANGLAATGGVGGGG
GSGSGGGGCGSGSGSGSGKRKSKARTKCFGGTVFRCCLPCRGGGSAAPATSPPQTPAQTP
DELKVIPEDCNLEKSAEQKRDLLERNNKEDDLLNRTVSGSELDLYGGAGGGTKKHSLADT
IDTSVTTPISLKTLINDVDEELDQQLSAADIAAASLASGLVARRAEPETLSDASVSPTAV
VQQQQQQQQQLQQPLLQSQPHFVPSSGNILSQVTLYSGSNPSTNPCQSAVQNQGQNSNPN
PNQNPNTNPNQNQQRCSCQPQTSPLPHIKEEEESDQANFKHQTSLKEHQPLPPPITIATG
YCGSCESVHHSSATSSSAGTVPPGGQQTQEYIAGTSSTPSPRIKLKFRKPHKSCWSRIVL
APIGSAGGSSSATTVIGSNSNETLASSSTTGGTATTTQNSSSVSVAAHHRLTSSSASALA
TSHPSNSQLLPTSKMQAEQGSIGDLQKYHSRYLKNRRHTLANVRFDVENGQGARSPLEGG
SPSAGLVLQNLPQRRESFLYRSDSDFEMSPKSMSRNSSIASERFKEQEASILVDRSHGED
LIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYT
RLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYIC
STFLDKQQEFDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLS
HTNSFTGERLPTFGVETPRENELGTLLGELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSR
ELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLE
VGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIF
CNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQV
LENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQ
VGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMIPPSPPPSGVDENPQEDRIR
FQVTLEESDQENLAELEEGDESGGESTTTGTTGTTAASALSGAGGGGGGGGGMAPRTGGC
QNQPQHGGM
>P27815|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|Swiss-Prot
MEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAERERQ
PHRPIERADAMDTSDRPGLRTTRMSWPSSFHGTGTGSGGAGGGSSRRFEAENGPTPSPGR
SPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
FAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
PSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTD
QEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYML
TLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEE
ISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAELEAVYLT
QQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLP
STAAEVEAQREHQAAKRACSACAGTFGEDTSALPAPGGGGSGGDPT
>O89084|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus musculus|Swiss-Prot
MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERSEPERS
PHRPIERADAVDTGDRPGLRTTRMSWPSSFHGTGTGGGSSRRLEAENGPTPSPGRSPLDS
QASPGLMLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVASEAHGEDLIVTPFAQVL
ASLRNVRSNFSLLTNVPIPSNKRSPLGGPPSVCKATLSEETCQQLARETLEELDWCLEQL
ETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTP
RQRPFQQPPPAAVQQAQPMSQITGLKKLVHTGSLNINVPRFGVKTDQEDLLAQELENLSK
WGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFHIPVDTMMTYMLTLEDHYHADVAYHN
SLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELAL
MYNDESVLENHHLAVGFKLLQEENCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLA
DLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFF
QQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NRDWYHSAIRQSPSPTLEEEPGVLSDPALPDKFQFELTLEEEDEEDSLEVPGLPCTEETL
LAPHDTRAQAMEQSKVKGQSPAVVEVAESLKQETASAHGAPEESAEAVGHSFSLETSILP
DLRTLSPSEEAQGLLGLPSMAAEVEAPRDHLAAMRACSACSGTSGDNSAVISAPGRWGSG
GDPA
>P54748|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rattus norvegicus|Swiss-Prot
MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYPDSAERSETERS
PHRPIERADAVDTGDRPGLRTTRMSWPSSFHGTGTGGGSSRRLEAENGPTPSPGRSPLDS
QASPGLVLHAGATTSQRRESFLYRSDSDYDMSPKAVSRSSSVASEAHAEDLIVTPFAQVL
ASLRSVRSNFSLLTNVPIPSNKRSPLGGPPSVCKATLSEETCQQLARETLEELDWCLEQL
ETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNEVEIPSPTP
RQRAFQQPPPSVLRQSQPMSQITGLKKLVHTGSLNTNVPRFGVKTDQEDLLAQELENLSK
WGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFHIPVDTMMMYMLTLEDHYHADVAYHN
SLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELAL
MYNDESVLENHHLAVGFKLLQEENCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLA
DLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFF
QQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NRDWYHSAIRQSPSPPLEEEPGGLGHPSLPDKFQFELTLEEEEEEDSLEVPGLPTTEETF
LAAEDARAQAVDWSKVKGPSTTVVEVAERLKQETASAYGAPQESMEAVGCSFSPGTPILP
DVRTLSSSEEAPGLLGLPSTAAEVEAPRDHLAATRACSACSGTSGDNSAIISAPGRWGSG
GDPA
>P12252|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila melanogaster|Swiss-Prot
MSQESNGGPAAGGGAAAAPPPPPQYIITTPSEVDPDEVRSMADLELGSPEKQVQVQSQKF
SSTSSTTKVATHSFSMSSSAGTTGQQSKQDSAQQIQQLQQLQQLQQLQQQQQQQQSQRII
SSSTRSQSLQSSTIVGEATTITSGAAQILSASAAASLAQQLKAQSSTSIITSSEQRTSTS
TSSSSSTRYIASGSSNLAGGNSNSASSASSKTRFQSFLQQPEGAHGFLTAHQKHVRQFVR
STSAHSEAAAGVAGARAEKCIRSASTQIDDASVAGVVESAGNLTDSSATGGSMQLSMSKL
GLQQSSSILISKSAETIEMKSSSAGMRTQLTLSGGFLAPPGNRKITILSPIHAPPGLHDM
LKRAQGRSPLSPRISFPGSDSDLFGFDVENGQGARSPLEGGSPSAGLVLQNLPQRRESFL
YRSDSDFEMSPKSMSRNSSIASERFKEQEASILVDRSHGEDLIVTPFAQILASLRSVRNN
LLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLET
IQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICSTFLDKQQEFDLPSLRVED
NPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGERLPTFGVETPR
ENELGTLLGELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMST
LEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLT
NQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIV
LSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPL
YKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLV
HPDAQDILDTLEENRDYYQSMIPPSPPPSGVDENPQEDRIRFQVTLEESDQENLAELEEG
DESGGESTTTGTTGTTAASALSGAGGGGGGGGGMAPRTGGCQNQPQHGGM
>Q07343|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|Swiss-Prot
MKKSRSVMTVMADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQS
ERARTPEGDGISRPTTLPLTTLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSAGLVL
HATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVR
NNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKK
KQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSH
NRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHV
LLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS
SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI
SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQSP
SPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLG
ETDIDIATEDKSPVDT
>P14646|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rattus norvegicus|Swiss-Prot
MKKSRSVMAVTADDNLKDYFECSLSKSYSSSSYTLGIDLWRGRRCCSGNLQLPPLSQRQS
ERARTPEGDGISRPTTLPLTTLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVL
HAAFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRIVR
NNFTLLTNLHGAPNKRSPAASQAPVTRVSLQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKK
KQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSH
NRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVAQSTHV
LLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS
SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI
SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQSP
SPPLDERSRDCQGLMEKFQFELTLEEEDSEGPEKEGEGPNYFSSTKTLCVIDPENRDSLE
ETDIDIATEDKSLIDT
>Q9W4S9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila melanogaster|Swiss-Prot
MIATLFIIFAFIRAFPWSRKRGRPALALTLMPEGGEDHRGDLNQKGENNNRPRPSISLAN
NGEAMAPRTRRKSSKFHEVTFSGSVGGGDSDGGGEAINGGNLDVSPSKRHSLSTTTSNSS
SAPYRYLSGSSRSRGSRGDCHEYYQLQQHSSSLSNGNRGNRGLSQRSDTMATEAEGEEFD
VDPMDEDDEDQTYDRETEEFYSNIQDAAGTGSSSRSKRSSLFSRSDSSATTTSSSGGGTF
TGGKRRSAASILSSSMCSDLMTSDRRSSTATEYSVKSVTTGNTSQRRSSGRIRRYVSRMT
IAGARRRTTGSFDVENGQGARSPLEGGSPSAGLVLQNLPQRRESFLYRSDSDFEMSPKSM
SRNSSIASESHGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGN
PPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFS
ESSRSGNQISEYICSTFLDKQQEFDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRG
PPMSQISGVKRPLSHTNSFTGERLPTFGVETPRENELGTLLGELDTWGIQIFSIGEFSVN
RPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVL
LNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLA
VAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGS
GVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDIS
PMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQSMIPPSPP
PSGVDENPQEDRIRFQVTLEESDQENLAELEEGDESGGESTTTGTTGTTAASALSGAGGG
GGGGGGMAPRTGGCQNQPQHGGM
>Q08493|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|Swiss-Prot
MENLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERD
LSPRPELRKSRLSWPVSSCRRFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESF
LYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGA
AKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRI
LNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTAEEAPQPMSRISGLHGLCHSA
SLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLL
KTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILA
ALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNL
SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQN
LVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGF
IDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFEL
TLEEAEEEDEEEEEEGEETALAKEALELPDTELLSPEAGPDPGDLPLDNQRT
>Q3UEI1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus musculus|Swiss-Prot
MRRSGTALSFLWTERVREPVDSGVAPVSPLGGGVILRRFSGTLLLPPLSSRLGSSGEAES
AAHVVFTIGTQGTQRNLGSAQSSFDLENGLPGGKGLLDAQSGPSLGRALQPPVHHVQRRE
SFLYRSDSDHEPSPKAVSRTSSAASDLHGEDMIVTPFAQVLASLRTVRNNVAALAHGPGS
ATRQVLLGTPPHSSQQAAPTEDSGLQLVQETLEELDWCLEQLETLQTRRSVGEMASNKFK
RMLNRELSYLSETSRSGNQVSEYISQTFLDQQAEVELPQPPTEDDPWPMAQITELRRSSH
TSLPTAAIPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAVIFSVFQERDL
LKTFQIPADTLLAYLLTLEGHYHSDVAYHNSMHAADVVQSAHVLLGTPALEAVFTDLEVL
AAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFRN
LSTKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQ
SLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASMEKSQVG
FIDYIAQPLWETWADLVHPDAQELLDTLEDNREWYQSRIPCSPPHTMGSDRFKFELTLEE
AEEEEEEEDEGQCTALNRESSELPST
>P14644|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rattus norvegicus|Swiss-Prot
NSSRTSSAASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHGAGSATRQALLGTPPQSSQ
QAAPAEESGLQLAQETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLNRELTHLSETSR
SGNQVSEYISQTFLDQQAEVELPAPPTEDHPWPMAQITGLRKSCHTSLPTAAIPRFGVQT
DQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAVIFRVLQERDLLKTFQIPADTLLRYL
LTLEGHYHSNVAYHNSIHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPG
VSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFQNLSTKQKLSLRRMVID
MVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPL
PLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWAD
LVHPDAQELLDTLEDNREWYQSRVPCSPPHAIGPDRFKFELTLEETEEEEEEDERH
>Q08499|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|Swiss-Prot
MEAEGSSAPARAGSGEGSDSAGGATLKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPP
PPPSPQPQPQCPLQPPPPPPLPPPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRA
MDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLDPMTSPGSGLILQA
NFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
AALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSV
SEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRP
MSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPL
TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST
PALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGF
KLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL
LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMC
DKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAP
DDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPL
DEQVEEEAVGEEEESQPEACVIDDRSPDT
>Q01063|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus musculus|Swiss-Prot
MERDTCDVLSRSKSASEETLHSCNEEEDPFRGMEPYLVRRLSSRSIQLPPLAFRQLEQAD
LRSESENIPRPTSLPLKILPLIAVTSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQAN
FVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFA
ALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPM
SQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLT
VIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTP
ALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLL
LDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCD
KHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPD
DQEEGRQGQTEKFQFELTLEEDCESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVAEEESQPETCVPDDCCPDT
>P14270|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rattus norvegicus|Swiss-Prot
MEAEGSSVPARAGSHEGSDSSGGAALKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPP
PPPSPQPQLQPPPPPPLPPPPPPPGATRGRYASSGASRVRHRGYSDTERYLYCRAMDRTS
YAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHS
QRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTN
LQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMAS
NKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQIS
GVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMH
TIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEA
VFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQE
ENCDIFQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNY
SDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNA
SVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQED
GRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVE
EEAVAEEESQPQTGVADDCCPDT
>Q8IRU4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila melanogaster|Swiss-Prot
MLNKNSASSQSLPRVHSFFNMIPSIMQDDLALTILNDRDNMFSIKSQRSHGEDLIVTPFA
QILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTI
EELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICSTFLDKQ
QEFDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTG
ERLPTFGVETPRENELGTLLGELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLM
IPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFA
ACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQ
RQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHC
ADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYI
VHPLWETWADLVHPDAQDILDTLEENRDYYQSMIPPSPPPSGVDENPQEDRIRFQVTLEE
SDQENLAELEEGDESGGESTTTGTTGTTAASALSGAGGGGGGGGGMAPRTGGCQNQPQHG
GM
>Q86H13|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dictyostelium discoideum|Swiss-Prot
MFNNNNNDKINNTMMSNNPSGQIINLESIDCNSNLSNTTSIKDSNNNNNNNNNNNNNINN
NINKINPNIDRKVLDDFNSKSIKIIDNKLNKKNSKKNLYSKEVDDDINKINLNKKIIPNE
TNSNNSNNNNNNSNNNNNNNNNNNNFNYNNNINSNNNIINNNNNINNNSNNNNNNNNNNS
ISLYVDTQEKSKKKVNAESLRGPIIFQNFILYTFFLIVIGTAEGTSWAPEIRVANFVPYC
VMCVVLLEFNRLHKKPLLRIIFPLYTSNIPFAYMCIFSREARKYVLISLLFFASCLCIFL
QSGIPDLRKHIVIFCIIFMINYGCCILFMDWFYIDTTGTKPYRGRILATKIHWGEEATIL
VSMALLGCIFIVLEKFIKSYARCVAEQHYQIQCLQKEKEKLQTEINISLKKLDLDTPIEK
IMDILRSMINTSESENDKKQLIKVIAVLGSNKLYDPDFKFETCTDDAEVYSWLQSMLNRE
VGYSNVNNNNNMMMIENNNNNTIINNNLIEPTSPNFSKKLTSSDLIPRIRSMPEITDQGI
QELIINNFLEWDFPVFQLSEITDGNPLFYMSYFLFSRHKFFEKFKIGIDCFKNFMRKIES
GYDSTNPYHNSIHATDVLHNLNYFIEKSFGKFLTDIELFSMILAAIIHDFKHPGVNNHFQ
INSKSRLALKYNDKSILENYHLHQAFIIMNEPESGILLKLSDSVRKEIRETIIALVLSTD
MAKHFNLVGRFKSMANSFPTTTNTQQPSSSSSSSSSTTIPTSTITPTPNSTTSTTTTTTT
TTTTTNNNNNNNSNNNSLNNIINNCSSSNGSMGASGADNSNSNNTNNSNSNNQNQCGSSI
FLNSNKKDRLLLMKISIKCADISNPSKPWNLYTNWSNRVTSEFYKQGDKEKESNMDVSAF
MDRNKPATTKCQINFINIFVAPIYEIWSHHFPQFKLCYQNILSNLSRLEIEQQQQLQLQQ
QQQQQLQQQQQQQQQIHQQQQQQLHHHQQQQQFQHQQHQQQLQHQHQQQLNNQNQNQNQS
NSNNSNSFGLTQSNYLIVV
>Q8MM62|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dictyostelium discoideum|Swiss-Prot
MNSKYGDNIIDFLRYLEKFVKSLTKDNKIEEFKTFDIKSLLYPRNKDYFGNLSKFLLAVI
SARIGSNFINEDDIFEISELLKEFLGQELEHLPYLSYEELYVEIVEQVGEINGTVSEIIE
AITVTIDFLDTFEKVSQTIDRSNEKQKLLAYLSAPVNQLDNSVSGVFNENDYTDIQRFFT
ELTNENNQSPDSNISILINDFQSLLNILESQQASSSSSKMIINDSPRTQQRNGTTEQQKK
QQQQQYLQKNKEPFYSKDKIMQVSGPSYVFTPSDCNVSIQVGIPPDTLKRDQSICHFIVP
HFLISKDVSLSEVEFPIFYNKFVQKGKTKVVIICTVEQKQRIETILCESIFGPAPEHIYT
DEEITIPDYKIDLLTERLAIDPRANDEKLDSYVIFKTFDTFGVVDIDLPSASDPTKLINL
RIRNTKGLISFHEDYHVVQKQLHLKLQEQQQDQQDKSSSSTTDKQMINTSGNRIILKNNT
VSVIDSTIESQYVPVLPFGNDHEQVKKFKAPILGVTFLGVSHGLDFTHCSHTTGFIIWIN
GSGVVVDPPVGNTTYLQTNGIYGKTVEHIILTHCHADHDSGILQKIIERNKVTLYTTKTI
NESYMRKLKALTGLPEQSLKNYYTWVPVTIGNKIKILGAEFEFDYSFHVIPTIRFKLEIY
NKKISYSADTFYDLQKFKQLKDQGVLSKKRIERLKSFVFDADMIIHESGVAPIHTPMANL
LELPSEIRKKIRVVHCSSSVDTKGEIIRPKEGLENTEIIKVDRKYKGVAECIQIQTALNH
CSVFSKLSPAEVQRVFFLCKKIWVKRNDVIIKKGSPSDMFYIILSGKVLVYENEYEPIKS
TTSVGTVVTDTTTITTTVKTDAIKIPTIKLCAGETLGESALQLDKNIDASATVIAETDVC
LLVWKTMDLRTEFHSNLNTFISKVHMDLSHINSCRDAIIRAFQHNITQHINKEEVDSIAN
GSKDVSFAHHQVIFNEGDTSDSMYIIKQGRVRIHSKKNKNIIRYLNVGDFFGETAYRRSN
EDSNFLPTRSFTATAIDPTILLKLDIESIVNPRIQNIIEQKAKKNAEDNIRYHAYSPKIR
TPRTPRKVYPIEGLSI
>P0AEW5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O157:H7|Swiss-Prot
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>P0C1Q2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus musculus|Swiss-Prot
MAASRLDFGEVETFLDRHPELFEDYLMRKGKQELVDKWLQRHTSGQGASSLRPALAGASS
LAQSNAKGSPGIGGGAGPQGSAHSHPTPGGGESAGVPLSPSWASGSRGDGSLQRRASQKE
LRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRV
NLPQYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSL
FLVEGAAAGKKTLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIP
DAYQDRRFNDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKVPEGAPFTEDDEKVMQ
MYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKC
ERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESVEKSSYSDWLINNSIAELVA
STGLPVNVSDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFD
DADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANI
PLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRM
VLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSD
SALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLY
FERRTEFFELVRKGDYDWSITSHRDVFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFE
QGDRERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNAKLKPMLDSVAA
NRRKWEELHQKRLQVSAASPDPASPMVAGEDRL
>Q8VID6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rattus norvegicus|Swiss-Prot
MAASRLDFGEVETFLDRHPELFEDYLMRKGKQELVDKWLQRHSSGQGASDLRPALAGASS
LAQSSARGSTGIGGGAGPQGSANSHPASGGGESAGVPLSPSWASGSRGDGNLQRRASQKE
LRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRV
NLPQYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSL
FLVEGAAAGKKTLVSKFFDVHAGTPLLPCSTTENSNEVQVPWGKGIIGYVGEHGETVNIP
DAYQDRRFNDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKVPEGAPFTEDDEKVMQ
MYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKC
ERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESVEKSSYSDWLINNSIAELVA
STGLPVNVSDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFD
DADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANI
PLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRM
VLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSD
SALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLY
FERRTEFFELVSKGAYDWSITSHRDVFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFE
QGDRERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNAKLKPMLDSVAA
NRRKWEELHQKRLQVSAASPVPSSPSPAVAGEDRL
>Q1KKS3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Takifugu rubripes|Swiss-Prot
MAVPKMVFSDVESFLDSHPELFEDYLNRKGSSSMVEKWLKNHQAGKSEAEPKEEKSSVCK
DSWASKCDGLQRRASQKELRKTFARSKAINVNRTYDEHVNSRAQEPLTSMRRRALLRKAS
SLPPTTAHILSALLESRVNIPQYPSTAVDFKYYLKEHNEREFFLELVKDISNDLDLTSLS
YKILVFVCIMVDADRCSLFLVEGTGNKKTLVSKFFDVHAGTTVLPSMNSGEVQVPWGKGI
IGYVAEHGETVNIPDAYQDRRFSDEIDKLTGYKTKSLLCMPIQNSDGEIIGVAQAINKSS
SGELFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKI
VRKIMHRAQTLLKCERCSVQLLEDIESPVVKFTKSFELLSPKCSADAESSFKDSMEKSSY
SDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQFSDFHIRSVLCVPIWNSNHQIIG
VAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHAT
CSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDVDAMITAALRMFIELGMVQKFKIDYET
LCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFAMLTTAGFQETLTDVEILALIVGCVCHDL
DHRGTNNAFQAKTGSALSLLYGTSATLEHHHFNHAVMILQSEGHNIFCNLSSTEYSDLMQ
LLKQSILATDLTLYFENRNSFFELVSIGEYNWNVKTHRDMCRSMMMTACDLGAVTKPWDI
SRKVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPGLQLEWIDGICAPLYETLVK
LNPKLQPMVDMINANRVKWEELDKKRQHDHGASVPASPCSAAEGSETGGVPCCSNNTPPT
HVS
>D4P095|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas aeruginosa|Swiss-Prot
MSRHSNTPATDASVLLVQLSDSHLFAEDGARLLGMDTAHSLEKVVERVAREQPRIDLILA
TGDVSQDGSLDSYTRFRRLSAPLAAPLRWFAGNHDEREPMQRATEGSDLLEQIVDVGNWR
VVLLDSSIPGAVPGYLEDDQLDLLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQLRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGY
RWLRLHDDGRLETGISRVDDVVFEVDYDTAGY
>A0A5M9IAT3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas panacis|TrEMBL
MPSVSTVNPDAPALLVQLSDSHLFAEADGTLLGMNTRESLQRVVELVRRQQPHIDLMLAT
GDLSQDGTLESYQQFRALTAAIGAPMRWIPGNHDEPQIMAHAAVHSDLLEPVVDVGNWRV
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPSRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVKAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFSVSEQAPGYR
WLRLHADGRLETGVERLVGFTFTVDYGSNGY
>A0A1H2PB21|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas vancouverensis|TrEMBL
MPSVSILTPADPALLVQISDSHLFAEADGTLLGMNTADSLQKVIELVRAQQPQIDLVIAS
GDLSQDGTLASYQRFRQMTQQLDAPARWIPGNHDEPQVMAEATVQSALLEPVVDIGNWRI
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCFHHHPVSIGCPWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDQMRDGVRLIASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLMPDGQLETGVERVTGFDFTVDYGSNGY
>A0A7M7IT32|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Apis mellifera|TrEMBL
MGCKSSVLECVKGTGEEKRKESDVIEQGFLFGKTEYDILGRKLSFEDVGDEKNADYSTLI
GSHDTEPHPLTNSIPSLIKILLVFPKDDQQMDILATTSRRLGWSVSVAKDAEKALEFFQA
RGHELVIIDHRGQRAAEADIICRAIRASPFYYNSIIIALVKKSYLMHSESEKIVTLDLME
IGYTKTLMECAHERILINELVGIYTSGILPRTQLVAVNMLYMALDRCRDMIHVTDDKYII
QFANKISEKLLGYRINELWGKNITDLILYDNFIQMEQHIVKGREYDGNINCIRRNNQMLT
INCRVIPFAYFKKPTHYIFIYDTTYLSETIQPLLQPITHPKTVVIAQKRVSEINFKGIQE
VRRRLSKRDLQTLQLEAPITKVIALLTASIKEDTSSETRLQIEQAIDILKTTELYSPVFK
EPGDPATDFIEALITPKKSWDIRKPSIESVRETPAKTLAASTRMQIKGYRGPQEIAEILE
KSLEWDFDIFKLEILTEKRALLFLGMTIMNLFRVPARLGCEEKIVQNWLIVIEANYDITN
RYHNSTHAADVLQAAAMFMQTERLKQVLEPLDEVATLIAAAAHDIDHPGRSSQFLCNSDN
KLAILYNDLTVLESHHAALTFKLTLSDDNVNIFKNLERDTYKQVRQSVIDMILATEMTKH
FEHLAKFMNAFSTRIPEMYIEGSQDLDLSAAILPENVILVKRMIIKCADVSNPTRPLKYC
VEWARRIAEEYFSQTDEEKQLHLPVMMPMFDRITCSIPRAQIGFIDFIINDMVEAWDVFI
NMPEIVGFMRQNYDKWKEYNEKGITTLQDIEKIQEAIPELKLDSMNT
>A0A4V2HYQ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella hadar|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A1B8YYW1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas hydrophila|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRIASQVWRLPVGQFVPDPNATGY
>A0A5M8P585|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Ordinivivax streblomastigis|TrEMBL
MNNMVFFMMVFVIYTLINGYLFYRGWKTIPKLSPVRGGYSVLFFLIYASFLVAMLGRNVI
ALPIQTILYRLGIVWLGFMLYLTLWFVITDLIRGLIRWFVKRKSTICVYRVQVVAGYILV
SGVLMYGYYRFLHPAVVEKEIVIHKSGVQYSKLDVLVFSDLHLGVSIDKKRLQQYVQFIN
AQHADLILIAGDVVDNNVRPLEQKKMNEELDQLQAPLGVYMCLGNHEYLSGIEGSVKFLR
NTKINVLIDSVAPINDSFWIIGRDDKQGNPRRQSLKSLTAQTDPSQALLLMDHEPYLLEE
AEQEAIDLQVSGHTHHGQMWPFNYLVDKLFENSYGYLKKGATQVYVSSGLGLWGPPFRIG
TQSEIVVFHLTFSK
>A0A166I8T5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lactiplantibacillus plantarum|TrEMBL
MKLRKSIFGISCVLFGMMLLSGCQKQTKMTLPPVSHKTLTAMVISDDHVIAPRLHDNGKA
FTQYAANDAGADLKYSATIFRAFIAKALITKPDVVLISGDITNNGEKASHEYVAKQLRRL
TAKHIRVYVVPGNHDLNNPIARRFKGKHQYSTEATSPTQFKKIYHQAGYGQASETDPSSL
GYLVKPSKHTWFLMLNSAIYKSNYQQGNSTVGGGLTDGTLQWLTKVGKQAKQAHATLIPV
LHHNTMDHTVIHQDYTIGYAEDVRKAFTTAGIKLSLSGHIHAQNIKSTKVKNQSLTDIAS
GALILGSHYYGTLKINQSNGTATYHATPLNVSAYIKHHRGNKAMRAYQKYDHDVLYAAGY
NAALSQLYEDRDETQLSSAKVNQLARGMAAANIALFRGTPVKNSAAIQAWQQMPHNTSLR
GFVLATKKLHGNVTWSGSVQ
>A0A1G6JU19|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas chengduensis|TrEMBL
MPSLPTQSTDSSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIERVLQEQPQIDLILAT
GDLSQDGSEASYQRFRQLTSAIDAPTRWLAGNHDEIPPMQAACQGSELLEPVIDLGAWRI
VMLDSSIPGAVPGFLADSQLELLERALSEAPQRHHLICLHHHPVSIGCKWMEPIGLRNPD
ALFAVLDRYPQARTVLWGHIHQEFDQQRGNLRLLASPSTCVQFAPGSEVFQVDSEAPGYR
WLRLHADGRLDTGVSRVTGIHFEVDYSVKGY
>I4K4J2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas lactis|TrEMBL
MPSVSAVNPDAVLLVQLSDSHLFADADATLLGMNTRESLQRVVELVRAQQPAIDLILATG
DLSQDGTLASYQQFRDLTASLGAPARWIPGNHDEPQVMAQAAMHSDLLEPVVDIGNWRIT
LLDSAVPGSVPGYLQDAQLQLLAQALSEAPGRHHLVCFHHHPVPIGCAWMEPIGLRNPEA
LFAVLERFPQTKALLWGHVHQEIDSERNGVRLLASPSTCIQFAPGSEDFQVSEQAPGYRW
LRLHGDGRLETGVERVKGFAFTVDYGSNGY
>A0A1V1V8X9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium damsela subsp. piscicida|TrEMBL
MLTYSLPPRQSDSVVLLQITDTHLFANDAGSLLGVATKDSFHAVLAAIDHQARPFDAIIA
TGDISQDHSTESYQHFAQGIARWQQPCFWLPGNHDYQPSMKAVLPSPQIKPCEQVLLGEY
WQMILLDSQVPGVPHGELRAEQLDMLDRALAAHSERHALVLLHHHPLAVGSAWLDQHQLH
NADDFWQVLARYPTKVKSVLCGHIHQELDCMRQGVRVLATPSTCIQFLPDSDDFALDSKA
PGWRYLELTPQGDVHTQIHRLANDQFAPDLNSAGY
>A0A3Q9LG79|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar 43:a:1,7|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5W1HAN0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Bovismorbificans|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRKLELRANGVLETEVHRLQDIRFRPDTASEGY
>A0A2N7CGB7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIKPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPDRNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAILCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGSVTTQVRRLPNGQFSPDFDAGGY
>A0A0H0AQE5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter asburiae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLTGAKFRPDTASEGY
>A0A5H8NF73|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Hull|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A3G3DW37|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Tennessee|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A263HHE7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gallibacterium anatis|TrEMBL
MSDLFRDESTGVIKLLQVTDPHLFADEDGELLGINTFDSFRQVLSEIKKSGFESNYILAT
GDFVQDNSEAGYHRFVKEIVQLGKKIFWIPGNHDFQPKMEAVFDLYKAVIQPEKHLLLGE
SWQVILLDSQLYGVPHGMLSEEELKWLEQRLSLYPDRNTLIVLHHHLLPTNSAWLDQHNL
RNPYDFSEILAKHKNIKAIVYGHIHQEVNAVWQGIPVFATPSTCIQFKPDCAYFTLDNLQ
PGWREISLYPDGRLETKVHRIKDKVFLPKDNMNGY
>A0A3Z6XGD8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica I|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5I6Z084|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Brandenburg|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A0P7NBQ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADKRFQPDTASEGY
>A0A827B670|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYLHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLDWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7J0ANL3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MTQKFSNILKALLLTVLFTALTVSCKDDNPTPVGNGSQSGFTIIIPENIDLISGGTITIS
QEGGSITTSEKIYLETNGKFTPCNITDASDEHFTFAVPNNIESGTYTLHVTKNGKRTLLG
QIKITIVAHQIPIPEGATVYGIIETEDGEPVANVVVSDGENCTVTNSDGIYGIASEKNQG
YVFLSVPSGYEPLTEGVFPKMYQKTVLSKGIPENISFKLKKTVGQDNFKILYMGDKHLAN
RSQDILQYKKFLADVTAYKGNHSSEKIYAITLGDLTWDQYWKNGYELPNYVKTINENLKD
MIVYNVIGNHDHDPKSIGSNKSATNPMLTHVAPAWYSFNIGKAHFVVIDNIDCIAYDGVQ
DRPYSQNVYEPQIEWLKKDLSYIDKSTPVYVMTHGSLFSYNTSNPKAYNLRANTGSDKLI
EACTGYEVHFVNGHLHQQHTMLPTDSPANGYSHPVYEHNIPAVCADWWYSGYYTPGCHIT
TDGVPAGYAIFEFSGKNMKWGYKGTGMDEKVQFRAYDLNNVDFSNVTWKNLKDSKVIAEF
NKRYVTPYADGKRKNQVLINVWNWNNDCTIEVKTVNGETLAAKQVREYDPLSIAALSVPY
WDRDALTSIPGTGTTLRYHFFQVQCNDADTDLEITVTDKFGNTYKEKMERPRPFSTEEYK
IK
>A0A5H7NQF5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Cotham|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2T8XIB7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Gaminara|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A6R5I472|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aedes aegypti|TrEMBL
MDSRSIYGCFRVRSLFKKNNAAKSMESLYKPSVTTVDVLDMKKLDTMAEARNGNLIENNS
TSLPDIHATSDEDELLDAFRAESPVQLRRKYSPEEIVASTDEEDLDSGYTTAAPEVLELV
RNLDQQALKLNEIILENDENGKPKAYTRTNSNGSAFRPRSLERGLLTAARRPHRRRVTSL
HEIIEGRPLDFDDRLISDLKFPNLLPPNPPIKILIAFCKNDPVFEALVTASHRLNFEPTF
VKSAETAIEAFQNAATGGHHIIVVDARYPRIIEADVLGRSIRNSKGSQHTTMVAVVKKNL
FEKDDTAVISLLDVGFNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQALYTALHRS
REAVIITDDSLRAQYANRASEKVLNMKLDEIVGRSLNDLVTADISNILSHTTRHKDYEGF
ISTRRKSQETLHIHVRAVPVSCIGRNPTHLVLILEQTSGTTLSALASDALQALPHGKEVA
RGSLHSIRRGSFDVRSTASDGLRRTSLAKLSQLPLEAPITKVLSLLAQVQENCSADESKL
LDRVMEFLKREGLYSPQMKEIRTEDPVATDLIGALLTQGPTNILSSRRSSNDSIIRGGGR
PSTGSIVFNKTRESSQLSELLNSALSWDFEIFKLEELTEKRPLVCLGLELFRRFDVYNTF
CCDEVTFKLWLIEIEKKYHSDNTYHNSTHAADVMQATACYLQQLSNRETKVMDRMDEATA
LIAAATHDIDHPGRSSAFLCNSDDRLALLYNDICVLESHHAATTFRLTMADDKINIFKHL
DRESYKLARSIIVDMILATEMTRHFEHLAKFVSVFGTDVDSKETTHDNDDNQILIRRMLI
KCADVSNPTRPLKFCVEWARRIAEEYFTQTDEEKHRNLPIVMPMFDRTTCSISKSQIGFI
EYIIHDMMDAWNSFIEMPEIVRYMEHNYSKWKLFEEQGINTLSDIKRKQLTLNSETTGSS
SIEEL
>A0A1Q8NW38|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella dysenteriae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A1Q2RER5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Helicobacter pylori|TrEMBL
MLISIAFLLVLCLLNYISFRMLKSFLTLKKISQYAYLGFFILLSAGEAAFAFYRNTMPSH
LFVLTSACSFVSFIVFVFALSFYGFSYSIEKIDFLHSRRKSLKNFLKLGFYLALLGYFWR
GFYEGLARPKIKETPIYLDKLDKELKIILLTDMHVGSLLQKDFVDYIVEEVNQKEVDMVL
IGGDLVDENIEKVKSFLLPLNNLKSAYGTFYVPGNHEYYHGIEPILSFLDTLNLTILGNE
CVHLGGINLCGVYDYFARKHQNFAPDIDKALKKCNESKPTILLAHQPKQIRSLKESHSVD
LVLSGHTHAGQIFPFSLLVKLAQTYLYGLYKHSDTTQIYVSSGAGYWGVPLRFLAPSEIA
YLRLLPKNQA
>A0A8I1AEP2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter bereziniae|TrEMBL
MQSKILQQTDKDKVIIQITDTHLMDKPDAKFVGINPEESFHAVMEDVQQRFPNADLILHT
GDLAQAAYPETYARYLNYMRGFGIDFYHIPGNHDNLSFFPFHVPEPEPTVIELDQWCIIL
LNSTVSGRTDGKIQPEQLVRLKQRLEQLRDKFVIVACHHNPFEMHSKWLDQHKLKNADEL
KAVLEPFNNIKLLLHGHVHQESYNEWNGIQFISTPATCVQFKPLSQEFSFDPIAPGYRCL
HLKANGEFETYVHRLDHFNVTINEEISGY
>A0A198GA82|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteus myxofaciens ATCC 19692|TrEMBL
MESQLELSVSPKSTVRILQITDTHLFANVDDTLLGINTYRSYHAVLSSIRAQGLDVDLIV
ATGDLVQDQTFKAYQHFAEGISTLTPPCVWLPGNHDYQPAMIDALNQAGILSAKQVLIGD
DWQLLLLDSQIQGVPHGELSDCQLDWLTRCLESQKDRETIILLHHHPMASGCTWLDQHSL
RNSQQLSERVKGHSQVKMMLCGHIHQEMDEMWHGVRLLATPSTCIQFRPHCTNFTLDTVS
PGWRYLELSIEPNGQRKIETQVYRLEGTEFCPDLDSEGY
>A0A8G7FQX7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas aeruginosa|TrEMBL
MSHHSNTPATDASVLLVQLSDSHLFAEDGARLLGMDTAHSLEKVVERVAREQPRIDLILA
TGDVSQDGSLDSYTRFRRLSAPLDAPLRWFAGNHDEREPMQRATEGSDLLEQVVDVGNWR
VVLLDSSIPGAVPGYLEEDQLELLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGY
RWLRLHDDGRLETGISRVDDVVFEVDYDTAGY
>A0A1V3HR55|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salinivibrio sp. IB872|TrEMBL
MQPCQIENANGDCIRLLQITDTHLFADEQGSLLGVNTLHSYHAVLDAISATQRTFDAIIA
TGDLSQDHSALSYRRFVDGIQRWQQPCFWLPGNHDFQPEMRSVLQSGSLSHCSQVLLGEH
WQMILLDSQVSGVPHGELSREQLRLLEQHLSEYPQRHALVLLHHHPLEAGSTWLDQHKLV
NRERFWQIMAAHPQAKAVVCGHIHQALNVRHQGVQVMASPSTCIQFMPDSHDFALDNQNP
GWRWLDLHSDGRIESQVERVTGQQFRPDFDSSGY
>A0A653LDW9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas veronii|TrEMBL
MRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQVNEHPYEVILATGDLSQDHSPESY
QRFASMMAPLGRPIYWLPGNHDDSPLMTEYLHAAGISESKQLVGDHWQVILLDTQVRGKP
HGMIGDHQLAALDRALRQYPDRHALITLHHQAVPVGCAWLDQHNLKNADDLFAVLARHPQ
QKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGWRYLTLYPDGRVA
SEVWRLPVGQFVPDPNATGY
>A0A663FKJ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aquila chrysaetos chrysaetos|TrEMBL
MTAKDSSRELATPESEIYIRTFKEQMHLELELPKLPGNRPTSPKISPRSSPRNSPCFFRK
LLVNKSIRQRRRFTVAHTCFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFL
YRSDSDYDLSPKTMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNK
LLACRCGGPRCSVMAPGRREWESTACLRRERCISFLGKGVRCVSGRVARV
>A0A3M7T0L6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Brachionus plicatilis|TrEMBL
MQVLLVQNREDPAVIALKNAILNCGYSITCSRNIQETHEAIKKVNYDLVLIDCRRTHANT
NKTHNTSANQYDYENICRFIRKLFHYTVIIALTHNYEDREVPCVLPFLKMGFNKAIAETT
NLMRYKNDLLTLEHGEVSSVKRLQAAHTLFTALEYTSDPIEIMNEKFQLLYVNNAFEKLT
GLSLNEVSGQSFHNLHKLDKNEILNKTEHVKAGMAWEFSLPIQKSTGEVSNHSSITIPII
VQGDTNKIQNYVTITKTSDKVALKNLKSKNVFKSNEPNDENTHPILKKITSLNIPKKSCD
FERFADMIKSDSHTATSSIDDGTISDNEKQTDTSNDLTRSSPEFNPQLSTSSSNQFRKRS
YDIQSTGNEFPSRRHSMAKVHQQSIEAPIRKVINIISLAHESSKTELVRQNLDKALDILR
STELYNPLLLDGDKHTSDLVSGLMSNGLQKRFAKGSIVGTKPLLNNESNSVQNYVRNLSP
DIIQLLETEESWAFDIIALERLTNKRPLITLGLKTMNRFSVCQHLKISESMLVNWLTLME
SNYKPSNPYHNSTHASDVLHATAYFLSTDKLTEILDDVDRCASAVLENHHAALAFQLTRQ
SQNANIFQNLTRDEYRAIRAVVIDMVLATEMNKHFEHLNKFVNKFSISTDEKLAIKSLDM
LQLPENKILIKRILIKCADVSNPCRPLDIYKEWADRIASEYFQQTDEEKEKGLPVVMPTY
DRAVCSIPKAQISFIEYFIEDMFEHWDEFVDLPEVMSNLQANTVYWRESAEDESDQSSQG
STEAFSKQNEAILINRNDSIKEDSELELESIDK
>A0A1Q9GD83|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium proteolyticum|TrEMBL
MYSLPQTNPDSVVLLQITDTHLFANEAGSLLGVATKDSFHAVMDAVDAAARPFDAVVATG
DISQDHSERSYQRFSDGISRWSQPCFWLPGNHDYQPSMSSVLPSPQIKPCQQVLAGEHWQ
VILLDSQVQGVPHGELSDAQLAMLDEALASQPQRHALVLLHHHPLEAGSAWLDQHKLHNA
DAFWQVVDKYPQQVKAVLCGHIHQELDRLYHGVRVLATPSTCIQFQPDSNDFALDKLNPG
WRYLELMADGRVVTSVSRLQGECFAPQFDAGGY
>A0A5M7CY79|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas chlororaphis|TrEMBL
MPSVSTLTTDDPVLLVQLSDSHLFAEADGTLLGMNTRDSLQRVIDLVLEQQPRIDLMLAT
GDLSQDGTLQSYQLFRDMTRQIPAPARWIPGNHDEPQIMAQAATQSSLLAPVVDIGNWRI
TLLDSAVPGSVPGYLQDDQLQLLASALSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPH
ALFAVLERFPQARAVLWGHVHQEIDRQQGPLRLLASPSTCIQFEPGSDDFKVGETAPGYR
WLCLLPDGRLETGVERVTGFDFEVDYGSDGY
>A0A8B2SG58|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. GER_MD16_1505_Eko_090|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSAPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHPDGTLTTEVCRLTGAQFRPDTASEGY
>A0A2S6TKX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alphaproteobacteria bacterium MarineAlpha4_Bin2|TrEMBL
MPSTGKPLLPPVIVKGLKKLLSTHFMLIAQISDTHISPSAKEGPSRRRWLERCISAINDL
DPQPDTVIHTGDLTHKAGDDEFAEGLDIISKLKAPIFLAPGNRDERNKLRELFPDRDYLD
PKSPYVQYAVEHHDVRLIALDTITAGDKKGEFCNARVASLRSALDGDKRPTAIFMHHPPF
DLPVPGLEFQYNSRADADRMIGVLNGHGNVIRVFCGHAHRQFFEMLGDIPVSTLPSIAVD
LRFGEYPAEQANAPLFQLHRYAPENGFTTETLAA
>A0A2N1A7F4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Psychromonas sp. Urea-02u-13|TrEMBL
MNSKAVQLKADAQGDLAFLQITDTHLFADREKDLLGIKTVQSFEAVVKHASKYKNCQAVL
STGDLSQDHSAQSYSDFSKHIKTLNLPCYWLPGNHDMQSVMLPSLLAEGLAQTKVIESEY
WQVILLDSQVEGVPHGLLSALQLEFLQQTLIENPNKNTLICVHHHVLPVGSAWLDQHILK
NNDAFLDLIKPFSNVAAVLSGHVHQAIDTLKDGVRFITTPSTCVQFKPNSDDFSLDSVAP
GYRYLRLTASGEIETVVERINKDAFPVDADATGY
>A0A1Y0CXU1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oceanisphaera avium|TrEMBL
MTHTPQQLHSQLLAPHRTDRVVEVLQITDTHLFADKNADFLGIAPWHSARAVVDAILENA
TELTPLAHDFILATGDLSQDQTPASYRHFSSLMSELAPPVFWLPGNHDDGQLMQAELDAA
GISNAKHLVCGQWQMLLLDTQIPGETFGELSSAQLSLLEQAITHYPEHHLLLAVHHQAVP
VGCAWLDQHNLRNSEALKALLMQHKAAKVVLCGHVHQGFDEYHQGIRFLASPATCIQFKP
LSDDFALDSMAPGWRALSLYPDGRLSTQVWRLPHHAFAPDFSATGY
>A0A2J9L7V9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteus mirabilis|TrEMBL
MESQLELSVKHKNTVRILQITDTHLFANVEDTLLGINTYSSYHAVLNAIREQGLDVDLIV
ATGDLVQDQTFEAYQHFADGIATLTPPCVWLPGNHDYQPAMIDALNQAGILSAKQVLIGD
NWQMLLLDSQIQGVPHGELSDCQLDWLTRCLESQKHRDTIILLHHHPMPSGCTWLDQHSL
RNSQELAERLKDHSQVKMMLCGHIHQEMDEMWNGIRLLATPSTCIQFRPHCTNFTLDTVS
PGWRYLEMSLLSDEKGKIDTQVYRLAGTEFCPDLDADGY
>E8KFM6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinobacillus ureae ATCC 25976|TrEMBL
MNGFYSLGKKEPVVRLLQITDPHLFSAEHEKLLGVNTTDSFQAVLDQIRQTLFNYDLVLA
TGDLIQDHNPEAYHRFAEMVKQLAKPVFWLEGNHDRQPQMSLYLAKHPHIQAEKQILAGS
HWQILLLNSQVANAPSGNLSFGQLAWLNSKLTEYPERYTLVVLHHNILPTNSAWLDQHCL
KNSNALAEVLSRYPNVKAILHGHIHQEVDAEWKGYRVLATPSTCIQFKPNCDEFTLDLLP
QGWRELSLFADGRIETEVKRLNSNAFLPDFQSKGY
>A0A3A4CXP1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dickeya dianthicola|TrEMBL
MESLLTLPVARGARIRILQITDTHLFAGERETLLGVDTYRSYQAVLDAIVAQPGDFDLIT
ATGDLAQDHTQDAYMRFAEGIRRFNAPCVWLPGNHDFQPAMVDVLARLGIAPSKHVLLGE
HWQVILLDSQVFGVPHGELSEYQLEWLERSLQSQPERHTLLMLHHHPLPSGCSWLDQHSL
RNAHSLDALLLRFPRVRTVLCGHIHQEMDLDWNGRRLLATPSTCVQFKPHCTSFTIDNVA
PGWRCLELLPDGGVETQVYRLEGNEFLPNMDSEGY
>A0A502HSJ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas arsenicoxydans|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEADGTLLGMNTRNSLQKVIELVQVQQPSIDLIIAS
GDLSQDGTLESYQQFRDMTGQLDAPARWIPGNHDEPQIMAEAAVQSALLEPVVDVGNWRV
TLLDSAVPGSVPGFLQDEQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEVDQDRNGVRLIASPSTCIQFEPGSDDFKVGEQAPGYR
WLRLLPDGRLETGVERVTGFDFQVDYGSNGY
>A0A7Y4AQH4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. 99-70-13A1|TrEMBL
MNLSRTSKFDGNSIKLVQLTDTHLFAPSNGSLLSINTQDSFHAVVSAILEQNFDFEAILA
TGDISQDHSEESYQKFESGIEPLSKPCYWLPGNHDFKPNMSSVLPSPQIQCVDHVLLGDH
WQMVMLDSQVVGVPHGRLSDQQLELLDAKLSEHSARHTLVLLHHHPLLVGSAWLDQHSLK
DSEQFWDVVNKHSNVRAILCGHVHQDMNREHCGVQVMATPSTCVQFKPNSDDFALDTLTP
GWRELILKEDGQLETQVKRLPKGSFSPDFDAEGY
>A0A5J4QTU6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MKKISFLHLSDLHIGSNVQKGLISQTKEILFGDIKFILKQIGSLDVVFFTGDLVQSGAKD
EYQQLESFLLDLWHLLTTNGLDPILLCVPGNHDLERIENQHNPILKTLLNWESDQIKEEY
FWTENNEYLNFISERFNNFTEWYNTTSIKKPQNMHLGYLPGDFYCSLPINDIKLGVIGLN
SSFLQLDGSNFQEKLGIYNKQIHTLFKDSYKEWLREQQISVLLTHHAPNWYERNSKDEYN
SEIYCLNSFVEHLCGHMHEPINITTGINGFPAKRIFISPSLFGLEKYESTYTRIHGYTAG
LYCFEEEKIKKTIWPRISIKTTDGTIKISQNENFNIDKGALSLTEIISLNSGILEESNSS
NSFEESADNLFIEKKFIDNLPRTIYKKIDSYNAIRIQERNKAIEFLLTNRCCWITTKYGL
GEEEFIGYILDQTQINPGNCFSMECDEISTINDLIELFTKVFSLNITEFFNIINSLDHPL
LVLNRINENLIENIAAINEFIKLIFDFCSNLRIIIISGFPSDNRFFNQIELFPLEIPAVR
QYIENSSAIQSFFTHLEYEKIHRLSSGIPIYIDKIIEQLAFCSLSDISDMEFEISVNDQD
GTLPITIKNTIKKLKEEKETMNNRIFDLLSILSLLYNGETYEHIKRIIPTKPFHVDEITY
LLKHKLIETTPVNLIFDNDSKNRELIKIIKVSRVIRDYVLTLLTNDEKSVIYKSVCDLYL
GKNWRKSIKIIQSKDVELNLIVYQNIQIAIRFLLKHSIEARNELEITRMSHVSLRVVNEL
SNRCAYKDAASLAEDILSLLPEFQIKELENTKLFLRKSLGQNLRMGSFYDKSIEILKSIC
NDKKNKLSEHDRNSIRLSIAYAYKAMDQREEITKYADLIKESEKNKNSSLYLSAESIIAE
LINDRTTKISKLKAIRSKAIKYNFTTLITNITLKLCKLEPEKTQLKQLDKIIDESKNDIY
NKVRALTTKAEIILTTKAIGDITDKDL
>A0A0D1FFX7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio parahaemolyticus VP766|TrEMBL
MQSSNDSIKLLQITDTHLFAADEGSLLSVKTADSFSAVVHEVLRRKVGFDYILATGDISQ
DHSAESYQRFADGIAPLQKDCYWLPGNHDYKPNMGSVLPSPQIQAAEHVLLGEKWQLILL
DSQVVGVPHGRLSDQQLTLLEEKLTEFPERHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFDNVKGILCGHVHQDMNVIHKGIRVMATPSTCVQFKPNSDDFALDTTSPGWRELE
LHTNGDITTHVDRLPEGQFQPDFSSNGY
>A0A564WHZ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Defluviicoccus seviourii|TrEMBL
MLIAQISDLHLRAGGALTFERFDTADALGRAIDHINNLDPLPDVTLATGDLTDDGRPEEY
QALRAALDRLRMPAYVIPGNHDDRDNLRQAFADRGYLPADGEFLHYTVETWPLRLIGLDT
VIPGEIGGGLCSERLAWLVARLAEQPDRPTLIFMHHPPFPTGIRYMDAPPLEGAAELEAL
IRRHAQVRQIVCGHIHRTIAVNWAGTVAAVGPSPVFQMNLALAPGGRFKPVAEVCAIALY
LWENGIGPIAHTSIVREQPARAVKAAVPA
>A0A5J4R4R0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MYIVLTGDLVHSGKREEYEKVSLLLRKLSGFLKVIYPKIKIDYVFIPGNHDCNFTYDSQA
RKNSIKNLTYENLGDDNSVVDLCIDVQKDFWDFYHKWLTELPDSKIFYQKNDTETSICFN
CINSSWMSSFKENPGSLFFPIKKISCREKADINITLVHHPLNWFNPVMDENNVIEMRNFV
DNNSDIVLFAHEHEEDGYTKTDTKTHKETYYRYGCALFTRNNRNIVESGFKTFIINPETK
TVKEQEYSWIEEQKIYSNIHSTDLQIETSDTCKKKIENNHDFLINLKSIKIPLSFQNNIK
PNILAIYVYPDLDDISSKKKEKKNNIVYIDSKELLNSKSKLTILEGDSQSGKSTLIEILY
LGWLEKGYYPLLLKGEDIKDIEIDSLLRRNYKQQYKGRTFEEYQQYDDKFKIIFIDDLYK
SKLNNKGKKMLLIP
>A0A5J4PIN3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MLIELNNKKIFAFADTHGKHRQLDVPADADILVCAGDVCNEGNEAQIEDFFAWFAQLPAR
HKLFVPGNH
>A0A5J4QWR4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MKKLLLLCFTCVWGCLQLSYAQSSSLKFNSNGKFKIVQFTDLHYIYDNPESDIALERVNE
VVDAEKPDLIIVTGDVIYGKPADKSMRAVLDVLAKKKTPFVILFGNHDDEFGLSRSQLFD
IIKSYPYNATTTVEGLSGIGNCIFSLKGTNGKDEAILYCLDSHAYSSIEGIDGYDYIKPD
QIQWYRSQSAAFAKQNGSKPIPSLAFFHIPFPEYTQAASDEESVLIGTRGEKVCPPALNS
GLFTAMKEMGDIMGVFVGHDHDNDYAVYYKDILLSYGRYTGGNTVYNHLKPNGARVIELT
EGERSFKTWIHLKGNKIIHTINYPSDLVKSKD
>A0A5J4SIZ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MERRDFLKTVASGVLVVGISPSAVQAINSVQSPAHSSCPELRFRENGRFKIMQMTDTHYK
TTSGGGESTLELMRRAIQMVQPDLIVLTGDIIMTPDTRAAWTTLSGVLSEGKIPWAVVFG
NHDQEFELTKPQIIDLLAKQPYNLTENGPKNISGNSNYILQIRSSKSPKKTGAALYCFDS
GQKDGLLHPEKPDWAWIHFDQIDWYRKQSAVLTAQNGGEPLPALAFFHIPFPEYREVIDQ
PATVGLFMEKVSSPVINSGLFTSMCECKDVMGTFVGHDHTNNYIGCLHNICLAYGYVSGR
QASKGFKEMGCGVRIIELFEGERKFNTWLLQLSETGPNDLWNPLRQVEPKLLVSYPDSFK
QVNG
>A0A5C9HL05|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cholerae|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFAAEDGSLLSVNTADSFAAVVAAIGEEQVEFDAILATG
DISQDHTPESYQRFVRGIQPLQKACYWLPGNHDYKPSMHSVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEYPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRIHLGARVMATPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A7L6YZQ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. RHB20-C15|TrEMBL
MESLLNLSLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEGQEYDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKCVMVGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLAAAPERHTLLLLHHHPMPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDSIG
PGWRTLELFADGTLKTDVCRLQGTEFRPDTASEGY
>A0A2H5VXN7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR10|TrEMBL
MMPLRQPKPWRRGVTRGVARTLLELARQAVDETRDIEIVRERVWLSGLPGSFEGFTLVHL
SDIHHSAFVDADYIAHAVALANRLAPDAIVLTGDYVSHSRSYIGGVAERLGDLRARVGVY
AVLGNHDFWTGPEALTRALRRHGIEVLRNAHTYVRRGGEALGLVGIDDLTVGEDDLLAAL
RGLDRRWPTLLLSHHPNILWSAAHARVALVLAGHTHGGQINIPSWRQRLRRYWPILRGHG
RYGPTQIYVNRGLGTVLIPVRYRCRPEITLLELRRAPEADGSV
>A0A014M130|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia mallotivora|TrEMBL
MDSQLKLPVQSGACIRILQITDPHLFAGKNETLLGVNTWASFDAVLQAISAGQQPYDLIV
ATGDLAQDHTVEAYQHFAEGVSRLAAPCVWLPGNHDFQPAMYSTLAETSIADAKHVLAGD
NWQIVLLDSQVFGVPHGELSDYQLEWLDKTLAMEPNRHTLVLLHHHPLPSGCNWLDQHSL
RNSTMLEAVLQRYPLAATLVCGHIHQELDLNWNGRRLLATPSTCVQFKPHCTNFTIDSEA
PGWRWLELYDNGRVETGVERLQTRAFSPDPDAEGY
>A0A2M4CS56|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles darlingi|TrEMBL
MWFTGYCCGVKGRARTTATEEQERSKPGAVMGCTPSILSNGSNNQQQQQSRKDSSGLYAG
NVAAAAAAAAAASGNGSSSHGNECGASANNNKLGTVNQTMVNTAFPSARDGGTEKESSAK
KDSIVSITASGHITSFPIVSTTVRRPTAGSKLRNLISFCRGTSSSSGRYGHRKSSLALTP
EEEPLDSCPRLVSDLKFPNLLPPNPAIKILIAFCKNDPVFEALVNASHRLSFEPTFVKSA
EAAIDAFQNPTAGGHHIIIVDARYPRIIEAEALGRSIRNSKGSQHTTMVAVVKKSVFEKD
DTAVISLLDVGYNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQALYTALHRSREAV
IITDDTLRAQYANRASERVLNMKLDEIVGRSLGDLVTADISNILSHTSRYKDYDGYLTTR
RKSQESSQIHVRAVPVSCIGRNPTHLVLILESSASALASISAAGEALQTLPQGKEVARGS
LHSIRRPSFDVRSIASDGLRRTSLVKLSSLPLEAPITKVLSLLAQVQENCSLEEAKLLDR
VMEFLKREGLYSPQMKEIRPEDPVATDLIGALLTQGPTNILSSRRSSNDSIIRGGGRPST
GSIVFNKTKESSQLSDLLHTALDWDFEIFKLEELTDKRPLVCLGLELFRRFDVYNTFNCD
EMTFKLWLIEMEKNYHSENTYHNSTHAADVMQATAVYLQQLSNRELKIMDRMDEATALIA
AATHDIDHPGRSSAFLCNSDDMLAVLYNDICVLESHHAATTFRLTLADDKINIFKHLDRD
SYKLARSIIVDMILATEMTRHFEHLAKFVSVFGTDVESKEPLPPDNDDNQILVRRMLIKC
ADVSNPTRPLRFCVEWARRIAEEYFMQTDEEKRKALPIVMPMFDRTTCSISKSQIGFIEY
IIHDMMDAWNSFIEMPEIVRYMEFNYSQWKLFEEQGINTLSDIKRKQLSLAEEPSSIISL
EEKF
>A0A0H3ELK4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O83:H1 (strain NRG 857C / AIEC)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A6I5IRJ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. V28_P6S34P95|TrEMBL
MNVSPSLSPSDHIKLVQITDTHLFAPDDGCLLSVNTADSFRAIVQAIIEQQIPFDAILAT
GDISQDHSAESYQRFAAGIRDLQKLCFWLPGNHDYKPNMGSVMPSAQIQALEHVLLGKHW
QMVLLDSQVVGVPHGRLSDYQLGLLDEKLTQYPDRFTLVLLHHHPLLVGSAWLDQHTLKD
SDAFWHVVGQHRNVRAVLCGHVHQAMDCEYQGVKVMATPSTCVQFKPNSDDFALDLCSPG
WRELELHHDGEVSTQVKRLRKGAFVPDFTSSGY
>A0A6N3YY83|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aliivibrio fischeri|TrEMBL
MLSETLLNEESDSIRLLQITDTHLFAPEDGALLGVPTRKSFQSVVEQVLQRTPDFDAILA
TGDISQDHTVESYQHFVKGIMPLKKPCFWLPGNHDYKPSMGGVLPSPQISACEHLLIGQH
WQVIILDSQVVGVPHGALSDEQLTLLDNALSQHPQRHSLVLLHHHPLPAGSAWLDQHQLK
ESEQFWSVLAKHHNVSGIVCGHIHQELDRVVNGIRLLATPSTCVQFLPDSDDFALDSQAP
GWRTLDLLPNGDIETQVYRLKDCDFSADSEAGGY
>A0A3R1ANH5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Kidderminster|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A6P1Q375|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mixta intestinalis|TrEMBL
MDSLLELPVVSGASIRILQITDTHLFSGRHETLLGVNTWASFNAVLEAIEAEQPSIDLII
ATGDLAQDHSSEAYRHFAEGIARLPAPCVWLPGNHDFQPAMFETLARSGIAEAKQVLMGD
RWQLVLLDSQVAGVPHGMLSDYQLDWLEKTLAQTADRHTLVLLHHHPLPSGCSWLDQHSL
RNAHALAAVLQRYPLAKTLVCGHIHQEMDVDWHGCRLLATPSTCVQFKPHCTNFTIDAVA
PGWRWLELAENGAVQTWVNRLGNRAFTPDLDSEGY
>A0A4Z0AF03|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas kairouanensis|TrEMBL
MPSVSTVNPDAPALLVQLSDSHLFAEADGTLLGMNTRESLQRVIERVRVQHPRVDLMLAT
GDLSQDGTLASYQRFRDMTRQIDAPARWIPGNHDEPHIMLQAAEHSDFLEPVVDIGNWRI
ILLDSAVPGSVPGYLQGAQLQLLAQALSEAPGRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDSERNGVRLLASPSTCIQFAPGSEDFNVSDQAPGYR
WLRLHADGWLETGVERVQGFEFTVDYGSNGY
>A0A2S2PQG8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Schizaphis graminum|TrEMBL
MWDNCCRRSGSASDLSRDTVDAYSPINRSDSPLAQTPDNFNNFMFGCSKYIQDLRSNSTL
KKILVVTSKDDSVWQSITITARNLEWTVNRVTSTEEALECFHKGNGVPTVAFVDCRFQND
KAVDAHQIARSLRSIRRNAHVVLVALVRKSLVLRNEKDVTSILTSGFNKIIVETCNKNVW
IKELQQLEKEDVAMRSMLAQQDAVLAALDKTKDLVIITDLKHNIQYMNKSGSVILGYGAE
DMINKPLAVFHQLGDIDQITKKLEKNIEWDGKVSWKCKSGEHVYLHCRASPFRPFGKDTT
NYIYIQESIVDVHGFPRGSVPSIRKGSYDLKSINSDGAQSARRQSLAKLHNLPLEAPITK
VISLICTAQENSNDQVVQILDKVVDILRVTELYSSHLKTENIKYDDPVTSDLIGALITQG
PVHVTSTRRSSNDSATVKSQPYGLGVAKMNFMTSVTPQIKELLDMSLYWDFNVFKLEELT
MKRPLVHLGMNLLTHFEVHKTLGCDERTLHAWLTVIEGHYHAKNTYHNSTHAADVLQATA
IFLEKDRIKRLLDQLDEACCLIAAITHDIDHPGKSRLDQIKTKLKPCQMVMMYYFFISAF
LCNSKNDLAILYNDISVLESHHAALTFKLTTKDERLNIFKGLEKDTYKVVRQNIIDMILA
TEMTKHFEHLAKFVSVCNKPSTLDEAPVDGL
>A0A2Z6V398|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcystis aeruginosa Sj|TrEMBL
MQRRKFLLISGSLGGFSLAACAHQILQPVTSKNPPESAVKQAQKAKKVKIIVISDLNSQY
GSTTYDPEIDRAIPLIINHKPDLVLCGGDMVAGQKSSLTEAAINAMWSAFDRHIAAPLRA
AKIPFGFTIGNHDASGALSAGKFIYAKERKLARDYWQNPQHETSLNFIDKTGFPFYYTFT
QNDIFYLVWDASTHLISREQLNWAAKNLSSSDAKNAKMRLVIGHLPLYGIAVGRNRPGDY
LADAEQLRAFLEGHQVHTYISGHAHAYYPGKRGQLQLLHAGALGSGPRRLLNSEQAPRKT
LTIVDINPHQQETVYTTYDMKTQEVINITSLPPLIMAPNGQVLRRDIPSVN
>A0A564T4L7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Faecalibacterium prausnitzii|TrEMBL
MIKKILHFLARLLLLLLLTALVLGGILLYNLQMNKSFITTFYTVTVDKPVEDLRIVLLSD
LHLSQYGTDNADLVRKVRNLAPDLIAVAGDMDIDTDPDYSLVLSLMRQLVDIAPVYYAPG
NHEWAARYANGCDAIFDDIEATGVHWMNGTYEDAVINGKKLRIGGFFEWPRARLERENSR
AVADALNDETNALGDVCTILICHCPEVLDTSLADEKFDLVLSGHAHGGQVRIGGQGLWST
SQGFLPKYTSGVNQMGESQVVISRGLGDSEPYPRIFNQPELVVVDVN
>A0A7X5Z3G2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. Iso12|TrEMBL
MLKEAITYSIPEDKSVRLVQITDPHLFADPEGQLLGVNTANSLNAVINTIQAVKYPADML
LASGDISQDYSGESYRNFVEAIKPLNLPCHYLPGNHDDPRIMYLHMQGERVYGHRRVLAG
NWQIILLDSTVRGKPGGHMAESEIEIIRSAIAAEPDKHVLLVMHHNPVLVDCTWLDQHCM
DNGAHFLKEMGRYPQVKGMLWGHVHQQLDTEYQGETHKLSLMATPSTCIQFKPLSSYFAL
DALQPGYRLLELKPDGSMLTNVYRIPGERFAPDAEASGY
>A0A2J8WPP5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pongo abelii|TrEMBL
HGDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPSVSRVNPQGRPCHKVY
LNVSR
>A0A3M2D0F7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MEEAIYHITHTSPEAVQLLHITDCHLFHDPNGRLLGLNTEHSLKAVLEAAQKVPHDAVLA
TGDLAQDASAAAYQRLGRFLSRLNRPVFWTAGNHDDPAVMHRHFIGQHIQPHKCIQSTYW
QILMLDSSVRRQVHGYLSDKELAWLEKRLTAHPEKWALIVLHHQPVPVGSQWLDGIGLKN
SATLFALIARFPQVKGILWGHVHQEFQQKLHGLRLMATPSTCVQFAVGSSDFKAGTEEPG
YRTLKLFHDGSIETEVHRTRPMEFTVDYSIKGY
>A0A855M2I5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae complex sp. ECNIH14|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSAPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHPDGTLTTEVCRLTGAQFRPDTASEGY
>A0A510I2I3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio rotiferianus|TrEMBL
MQLSSDSIKLLQITDTHLFAADEGSLLSVRTADSFSAVVEEILHRQVQFDYILATGDISQ
DHSAESYQRFAEGIAPLEKDCFWLPGNHDYKPNMGSVLPSPQIQSVEHLMLGEHWQLILL
DSQVVGVPHGRLSDQQLTLLEEKLAENPQRHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVNRFSNVKGILCGHVHQDMNVLDNGIRVMATPSTCVQFKPDSDDFALDTESPGWRELE
LHSNGDITTEVNRLPDGQFQPDFTSNGY
>A0A5R9A8D5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas nitroreducens|TrEMBL
MPTQPTASDSVLVVQLSDSHLFAQENGRLLGMDTADSLTQVVRLVGEEQPVIDLVLATGD
LSQDGSVESYQRFRAITAPIAAATRWFPGNHDEMEPMREAAAGTDLLDPVIDLGAWRVIL
LDSTIPGAVPGQMTVEQIQLLERAIQAAPDKHLLISFHHHPVSIGSQWMDRIGIYNPERL
FAVIDRHPNVRCLLWGHVHQEIDRMRGDVRLLASPSTCVQFTPGSEDFCVDSPAPGYRWL
RLMADGEVQTGVSRVTDIEFEVDYSIKGY
>A0A8G1MJK0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. ERGC3:05|TrEMBL
MPSVSALNPDAPALLVQLSDSHLFAEADGTLLGMNTCESLQRVIELVREQQPQIDLVLAT
GDLSQDGTLESYQQFRDLSRPIDAPARWIPGNHDEPQIMAHAAVHSDLLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDQQLQLLAQSLSEAPGRHHLVCFHHHPVPIGCAWMEPIGLRNPD
ALFAVLDRFPQVKAVLWGHVHQEIDRERNGVRLLASPSTCIQFTPGSEDFQVSEQAPGYR
WLRLHADGRLETGVERVKGFAFTVDYGSNGY
>A0A6L2PD10|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Coptotermes formosanus|TrEMBL
VLLAFGKDDVQSEALSLACEKLGYECNLARSREAVLETFQSKSHEIIIIDTRNPKNIDGE
SICRALRSLKTTQYTVVVAVVRRSTSEKEDSSIEPLLSMGFNRVCLETSSVTQCMNELLQ
LYLSDVQPRLQLATAQAMYVALDKCSDVVHITDQNLNVQYMNRSSERFLGFNMKDVAGKS
LLETNSVDNKELMVQQLQRGREWEGLISWRRKVGDSVVLSGRVVPVCIPGRSPTHYVFVH
ESQNTMLDKRMSGTLVKNSELPRGSNNRKGSADMKSVSSDGLRRQSIAKLHNLSIEAPIT
KVIALITSVQENANIEDVQTLDKVIDILRTTELYSPQLKDDKGKSGDPVTNDLIGALLSS
GPSVTPIARRSSSDSGSVSKIGVSRNTFKTGSISHQMKELLDTSLLWDFDIFRLEELSMK
RPLVYLGMNLMGHFDVCSSLGCDESVLHNWLVIIEMNYNAKNTYHTSTHAADVMQATAGF
LERERLKQILDPLDEAVCLIAAAAHDVDHPGKSSAFLCNSNHELAVLYNDLCVLESHHSA
LAFKLTMSDDRVNIFKSLERDVYKAVRQNVIDMILATEMTKHFEHLAKFVNVFSIKKEDD
SPDGGRSSPDIGLLTAPENIALIKRMLIKCADVSNPTRPVRMCVEWAVRIAEEYFNQ
>A0A1C3HJ99|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia marcescens|TrEMBL
MESLFKLPVASGAAVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAIQAQRRDVDLIV
ATGDLAQDHSQEAYRHFAAGIAQLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLLGD
NWQVLMLDSQVFGVPHGELSEYQLEWMERCLQAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAILLRYPKVNTVVCGHIHQDLDLEWQGRRLLATPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGHVETQVFRLENDDFRPDMDSDGY
>A0A2H5WCJ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR12|TrEMBL
MAPWTERVRYATRLALPVVVGLVGAWLGGALFAPAEVRTGPFRVAVRPALGRGVTDLGLP
PFGRVVADTHVGPLDLSATLTDVGVRRLTEVVGRVGIQGLVDQVQADALDAVPRLALRLL
LAAVVGAGMLGALVFRRRLRAVGAACLTALVAVGGLEALAWVTYRPAAFTEPRYVGSLGT
ASHLIGPVREATDRIEDFRVGLQALIASATRAYTSIQAQPLPGAGSVRVLHVSDLHASPL
GMDFAREVADAFEVDLVVDTGDLTSFGTPLEDLITARIAAFGRPYVFVRGNHDSLALQAE
VARLPNAIVLDGNVAEVAGLRIYGLGHPAFTPSGTEEGIDPEAFEEEARGAAEAIREDLA
RLEEPPDIVAVHDDRMVEDLAGEIPLVVSGHFHRTTARVIRGTLFLRVGTTGGNGAGVFR
GLDVPLSAEVLYFSRPESRLIAYDVIEQDPETGSLSVTRHLISRDYGELVLTPSASVIPP
LTVTPG
>A0A8F6GVF9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylococcus sp. Mc7|TrEMBL
MPDSGTLRLLQITDSHILPDPEARFYGIDSAASLRAVIDHANRDRFDLVLFTGDLAQEPS
TESYRRLAELCAGLPAPCYWLPGNHDEPALARRILSQTPLLHEPVIRKGRWLIVCLDSTV
PGSAGGSLSEERLDLLERALSGHPSLHTLIALHHHPVPSGSAWMDTMILDNAGEFFAVLG
RHPQVRAVLHGHTHQVSDMEIEGKRMLGTPSTCIQFRPASRSFALDEERPGYRWLELGPE
GSLETGICRVAVPPASDDA
>A0A6F9BZG4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Coregonus sp. 'balchen'|TrEMBL
MSQRKLTRQMNLWETPEGLTTPTLTPTSLYVTSINSPVSPDHDHTRGHVNSMFFRRMKLN
CSIEHRRSSHSHLPLSPMDSQASPVLGLHPSFTTEGCRSRGERRESFLYRSDSDYDMSPK
TMSRNSSINSEGHAEDLIVTPFAQVLASLRTVRSNFTILANVTTPTNKP
>A0A2H6AHN4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR36|TrEMBL
MLLAVTADLHYPKTPNYTLTHLSLAIERQRPDVLVLAGDLGDSSVHTAASLAFFRRLPCP
KLVLVGNHDLYPDTNSSMSFSPVSEPAVQQPVQRLGGYSSAQLWQKELRRQIEAQDGVWL
EDTIFVRNSVAIVGTIAWYDYSAADPQLGYGPEIFAREKRFFSTDDRINWPWSDQEFAAM
VSRDFLRRLDAAVAHPQVAHVVVVTHVPILEQQLLRRPGDKHWGFSNAYFGNLTLGREVL
RREKVCLIVSGHTHIGRRSYFLAPNGRVVQAAVVGRRQRQPTFLLCRVPAPALPAPVVSF
S
>A0A3B4BD33|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Periophthalmus magnuspinnatus|TrEMBL
PFDVENGLSVGRSPLDPQTSPGSGLVLQANYPHSQRRESFLYRSDSDYDLSPKAMSRNSS
TASELHGEDMIVTPFAQVLASLRTVRSNFAALTHLQDRAGNK
>A0A2R8CNK0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kushneria phyllosphaerae|TrEMBL
MLIIQLSDSHLKADPAGVYRDVEVEARLISMLAVVAGYQPDLIVVSGDVSDDGSLASYQR
AAGHLDALGCRWVWLPGNHDHPATMAEVRALEPIIHLAGWQILLLNSWVEGEEGGRLGRQ
QLAHLDAQLAGEASPALLVLHHPPVSVEADWMNEIGLEDREAFWAGPGRSDHLQAVLCGH
IHHEMTCLHQGVPVMSVPAIAAQFVPESQEFAVDSHAPGGFRLIHLGVDDAGQPRLSTRV
EYVPVQQPG
>A0A7X3HXT5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. R-28-1W-6|TrEMBL
MLIVQLSDSHLFAEEGGKLLGMDTCDSLQRVIERVQQEQPRIDLMLASGDLSQDGTLGSY
QRFRQLTDPVARQARWFAGNHDEVPAMREACAGSDLLEPIIDLGNWRITLLDSSIPGAVP
GFLAAEQLELLQRSLSEAPERHHLVCFHHHPVSIGCSWMEPIGLRNPDELFAVIERFPQV
RAMLWGHVHQEFDQQREQVRLLASPSTCVQFAPGSEEFQVDRSAPGYRWLRLHADGLLET
GVSRVTGIDFEIDYSVKGY
>A0A848MF68|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rouxiella aceris|TrEMBL
MESLFKLPLVDGAKVRILQITDTHLFAGEDQTLLGVNTLRSYRAVLDAICAQQREVDIIA
ATGDLAQDQSVEAYHHFAHGVSRFAAPCVWLPGNHDFQPAMVDALAEAGIHPSKQVLLGD
NWQILLLDTQVFGVPHGELSEYQLEWMKRCLDEQPQRFTLIMLHHHPLPSGCTWLDQHSL
RNAHTLARVLQNYPKVTTLLCGHIHQELDLDWYGRRLYATPSTCVQFKPHCTNFTLDTLA
PGWRYLTLHPDGRVETEVCRLQSDEFRPDSDSEGY
>A0A1V3JSZ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rodentibacter myodis|TrEMBL
MKNTFVHRSANSVVKLLQITDSHLFKDEKTELLGVNTQAGFAQVLAEIQQEKREFDVIFA
TGDLVQDGSDEGYQRFVEMIKPFGKPVFWIPGNHDFQPKMVENLNQSPMENAKHILLGDH
WQALLLDSQVYGVPHGELSQYQLELLKLTLAEYPERYTLIVFHHHLLPTNSAWLDQHNLR
NSHDLLDVLAPFKNVKAILYGHIHQQVDGQWKGYQVMATPSTCIQFKADSNHFALDTVQP
GWREIDLYSDGSIVTKVKRIQQTRFLPNMQEEGY
>A0A6J2XP91|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sitophilus oryzae|TrEMBL
MGDQGLNQSSKIYMASETNRDFSPNEKFSSPRERGNSEQADTDRKHRKIRVKLPKRGPNE
LKYGLIIPNIKHQLKLLLVFAQLDPVSETFTKAAEKLGFEVTLCHTDISALEEYQTKSHD
LVIVDNRITKAFDNDLLCRSIRNTRGSQHTVMIAVVKKSAFERDDITITSLLESGFNRCL
IETTNLLTCVNEMILLKHSDIRIMAQHATCQALYTALDKCKDLVIVTDDTYKFQYMNTAC
ERQLGLRQEDTLGKTLQEQLVYDTVQINTMGSSLLRAREWSGPMTLKRKSTQDPIVTSCK
AVPFSCAGRMPTHFILVFDTNSIDPNMLSQSRGSIHSIRRGSTDVRSVGSDYLRRTSLAK
LNALPLEAPITKVIGLIDQIRESLGSNPQAIQLIDRVEDILKSSELYVSHVKEDSKVKAD
EPVVSDLITALLSKTPQPTLSASSRRSSNDSSVFRPSRTGLIKAPAAIRDLLETSLTWEF
DIFKLEDLSRRRPLQHLGMNLFNHFDVCGSLNCDEKTLSNWLTVIEANYHIENSYHNSSH
AADVMQATAGFLEKERMKSIMEPLDEATSLIAAAAHDLDHPGKSSAFLSNSNNPLAILYN
DVTVLESHHSALMFKLTLGDERVNIFKNLDRDTYKLARHNVIDMILATEMTKHFEHLAKF
VNVFCPRSSIGSDMDQPDDYNALLSPENTTLVKRMMIKCADVSNPTRPLRICVEWARRIA
EEYFQQTDDEKMRGLPVVMPMFDRATCSIPKSQIGFVDYIINDMFEAWNAFIDMPELLTY
MRQNYIRWKEFDEQGHTTLSDIQKLQATVLSPSVSSAIKSD
>Q3YXK8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella sonnei (strain Ss046)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A2X5A162|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia rubidaea|TrEMBL
MESLFKLPVASGAKVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAVRAQQREFDLVV
ATGDLAQDHTPEAYRHFADGISQLPAPCVWLPGNHDFQPAMVDALAAAGITPSKHVLLGA
HWQVILLDSQVFGVPHGELSEYQLEWMERCLQAHPDRYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAILLRYPQVNTLLCGHIHQELDLAWQGRRLLASPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVCRLDNDDFRPDMDSDGY
>A0A2S6WZM4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces sp. MH60|TrEMBL
MIRVAAVGDIHMGPDSEGLLRPAFETLPDCADLLLLAGDLTRHGTPEEARVVAREVRGLP
VPVVAVLGNHDHHDEQPEKVTAILKDAGVTVLEGEGTVVECAGGRVGIAGTKGFGGGFVG
RSAGEFGEPVMKEFVRTTRRSADSLHAALKELDEEDCAARVALTHFSPVADTLAGEPPEI
HPFLGSYLLAEAIDTAGADLAVHGHAHLGTEHGMTAGGVRVRNVAQPVIRRAFNVYRLGA
G
>A0A7Y4DV98|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio coralliilyticus|TrEMBL
MKVTSCSSDGSIRLLQITDTHLFEATDGSLLSVNTADSFNAVVDAIVEESPAYDAVLATG
DISQDHSEVSYQRFEQGIVPLKKKCFWLPGNHDFKPSMNSVIPSQQIQQIDHVLLGDTWQ
MIMLDSQVVGVPHGRLSDKQLNLLEEKLSQYPERYTLILLHHHPLLVGSAWLDQHTLKDS
DDFWQVVDQHNNVKAVLCGHVHQDMNVMRNDVRVMATPSTCVQFKPNSDDFALDYQSPGW
RELLLRDNGEVETQVKRLPAGCFQPDFNSAGY
>A0A6N8HKR4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lentibacillus sp. JNUCC-1|TrEMBL
MTKFIYFTDTHIGANPVGFCQQPAYPQSINNLVTYLKNVVVSEQIDFVVHGGDLVQTCKK
DLIQEAVKLMNFSVPVYLCLGNHDLDHKNAVNTWMENAPNLFCENKPAYSVIDKTSALHI
IPNHWIDNHLYYWENKQNPYFTQAQIHYLEKKFQAHPDKKHILITHSPVFGMSKKQSGLD
HVIHEPPLSFQDTILQTSLQYPELKLVLSGHNHLNTLKQRNGTLFVSGSSFIETPFEYKI
IEVTERCINLRTHSIGQTALLDFVPSYNYEATYVQGREQDRHVTLNF
>A0A2N8Z8C6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio tapetis subsp. tapetis|TrEMBL
MRLALEATESIKLIQITDTHLFEPEDGSLLSVTTLDSFHAVVDAVQATKFDYSAILATGD
ISQDHTDTSYQRFANGIAPLKKPCFWLPGNHDYKPSMQSVMPSEQIVATTHVLLGDKWQI
ILLDSQVAGVPYGRLSDEQLTLLDEKLSTHSDRHSLVLLHHHPILVGSAWLDQHTLQESE
QLWSIIGKHNNVNGILCGHVHQDFDVKHQGVRVIATPSTCVQFKPNSADFALDNQSPGWR
MLELFANGELKLEVGRLESDSFLPDFTSAGY
>A0A732GNG0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae serovar 18:z10:z6|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A2R9C849|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pan paniscus|TrEMBL
MAQQTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISP
RNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVH
SQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALT
NLQDRAPSKRSPMCNQPSINKATITGSWMELNPYTLLDM
>A0A411PG99|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella maritima|TrEMBL
MQSEAKNYSKLKNDSVRLVQMTDPHLFADPESQLLGVNTAQSFNAVLDTFIASNYQADLL
LATGDISQDYSPDSYQQFADYVTKLDLPCHYLPGNHDDPRLMNLHMQGDHMFGHQRIIIG
EWQILMLDSTVRGKPGGFMAQDQFELIDGAIKSEPNKHTLLVMHHNPVLVKCKWLDQHCM
SNGDVFLEQVGQYPQVKGILWGHVHQAYDSEYQGAHGIVSLMATPSTCIQFKPKSPYFAL
DGLQPGYRLLELGSDGSIQTQVYRVAGDRFSPDNEASGY
>A0A221UXP2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arenibacter algicola|TrEMBL
MHTKTVGNSPESYYIRNSFLFNPNLMKLKMMGTIRLTQKLGFILFVILVGCKSQQEKVPH
GHSHDTGHDHSHSHSHYPEHDSIMAHKLMFPSRVPDRVIANLTADAAHSLAVNWRTDQQV
EAGFVEIAVATDGPEFLLKDVRRVEAKSEIFQNQNSKEPLVKAVYHSAEVNNLQPKTTYV
YRVGNGKEGNDGWSEWFQYTTASDTSGEPFSFIYFGDAQNNVKSLWSRVIRNSYRKFPKV
NFMLHAGDLINDRDANLEWGEWFYAGSFIHATVPSVMTPGNHEYRDGVLTSLWKPQFTLP
ENGPIEELKETCFAIDYQDMKLISIDSEGYDESMEARSAQIKWLDSVLQSNTKKWITIFT
HYPVYSTKEGRDNWELREGIKPLIDKYGVDLVLQGHDHTYARGYADNKGKGLTVLDDAGT
VYAVSVSGPKMYESQDQDWMVRRGEYTQLFQIITVTNDTIKYEAYTPIGNLYDAFDLIKK
DGKKQLINRVPDSPIRLKKDFVREEK
>A0A602ML48|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Gaminara|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRTQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A4Y9GYI4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurella sp. WM03|TrEMBL
MRNTFVYRSGKPIVKLLQITDSHLFKDENNELLGVNTQTSFAQVLKEIQQEDTEFDVILA
TGDLVQDSSDEGYQRFVKMVKPFGLPVFWIPGNHDFQPKMVENLNQPPMEKAKHILLGEY
WQVLLLDSQVYGVAHGELSQYQLDLLKTTLEKYPDRHTLIVFHHHVLPTNSAWLDQHNLR
NSHELFDVLAPFKNVRGILYGHIHQQVDSCWQGYKVMATPSTCIQFKADSQHFALDDAQP
GWREIELHSDGLIVTNVKRIRQAVFLPNMQEEGY
>A0A3N5E6U7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Buttiauxella warmboldiae|TrEMBL
MESLLNLPVAGGGQIRILQITDTHLFSGKNETLLGINTWMSYQAVIEAILAQQRHCDLVI
ATGDLAQDHSAQAYQHFAEGIAEIPAPCVWLPGNHDFQPAMFSSLLEAGISPAKQVFLGD
SWQVLLLDSQVFGVPHGELSDYQLEWLERKLAGAPERHTLLLLHHHPVPAGCSWLDQHSL
RNAAELDDVLQKFPKVKTLVCGHIHQELDLDWNGRRMLATPSTCIQFKPHCANFTLDTIE
PGWRWLDLHPSGEVTTEVCRLQGAVFNPDIASEGY
>E1JGU6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila melanogaster|TrEMBL
MGCSPSTLPPAPSAGQTGERGSLPLDASEKDESRLFCIKLRRSRLRRCSCGGVTLQPPSD
GNGSTAGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHSVVRRATGSTG
TSGTSSSGGNSRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLVFH
KSDSICEAITAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSSKNLDAEH
IARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQIL
HSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLE
DIFVSDLSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVP
GGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKII
NLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYS
SRRSSNDSIIRTGSSTRTAAIVPAKMKSNPIIMELLDESLSWDFDIFKLEEITDYHPLLY
LGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLT
NKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITF
KLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPRDHNP
QTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMF
DRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLAEI
MAKQPPVGKMANSKXHTAFRRLFSGLLKPLPAHAPGTSTIGENEMEDVL
>A0A556SSF0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gilliamella apicola|TrEMBL
MESLLQLPTKNKNYGKILQITDTHLFADGSCALLGVNSNASFLAVIDEIKKCSRTYDLIV
ATGDFVQDGTKEAYKFFAEQITTLNTPCVWLPGNHDNYDYMQSVFANYRLLDNKVVLLSD
KWIIILLNSQVEGQAYGLLADSELLFLQKNLDRYSDRNALVFLHHHPINSECHWLDQHIL
KNSIELEKIIQAYPQIKGLGWGHIHQSQDHQWYTCKAFSTPSTCVQFKPNSYNFGLADND
APGWREITLTNDGMLETEVFRINDNRFVPDLSQNGY
>A0A6P5VKR8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila obscura|TrEMBL
MRNCLPKLTNVFRRKSSAKSSATGPGHTNHSNDCHSDSDSEQYTAVAMSGSLAIPSPQYD
PARDNNNERPHRDGDSSYSRLISGPSNLESTAVAPNVRSRAVEESSFTEMRVETISGQAA
GPARLSIPIPGRNSISLPFAGLSSSKTPEEMELEYEANVKAEVGDIVTPLRRNNTSSTRP
HSMAFNGGGRSASLQPEIVEAIRNLDVQGLFLNNLAIEEDRTDIESDQSQGHEDAVVLRR
KVAGLERKSCSLYERRMPKTPKLHLMVAGKKPQPQPQQQQQHQQQQDGGDDDEFKVFQRN
LMDLKYPTVLPPNPQLKALLVFHKSDSICEAVASACQRHQLDVTLVKSKEEALDTLHKSY
ATAQCYHLIIIDARSSKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDA
GVNRCIAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQ
YANRATERLLNMRLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMH
VRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASD
GLRRTSLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKE
IRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKANPIIMELLE
ESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSN
TYHNSTHAADVMQATGAFITQLTNKDMMVMDSMEEAMALIAAAAHDIDHPGRSSAFLCNS
NSALAVLYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMT
RHFEHLAKFVSVFGGEEPREHNPQSDEETAILMRRMLIKVADVSNPARPMQFCIEWARRI
AEEYFMQTDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLIT
YMQINYSQWKKYDEQGVNTLADIMAKQPPMGKLANSK
>A0A8F9HCF0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. TM-G17TGC|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQFSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A1U7CUG9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paludisphaera borealis|TrEMBL
MPIHLLPTRRDFLSGLALGGVSTVLGCGNAEQPVAVGEPTPSALPSGYIALLSDTHINAD
PVVAENGGPKNNMTKNLRVAILDILKQPEMPRAVVVLGDLAHKDGQPGDYQQFLSLIRPL
REFGVPFHLAMGNHDDRAQFLQVLKPEDPGLGLVDDRYIGVVNVAGIRLVILDSLDKPKQ
VTGNLREPQRAWLAKTLDAEPQSSTVVLVHHNPKNASENAWQCLWDTEELLAILRPRKQV
KALVFGHSHRWDLRRDGDLHFVNLPAVGYPFAADQPLGWCRFEPTVDGATIELHRVDGGL
DKDLEPVDLKWRAT
>A0A399F3R5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Calidithermus roseus|TrEMBL
MLGVKLFVVRVFAIADLHLSRAFPKPMAIFGPNWEGHPEAVFEEWRKVVGEDDVVIVAGD
ISWAMRLPEALVDLRDLGELPGTKVLLRGNHDYWWPSISRLREVLPPRMHALQHDSLMIG
GVAIAGSRGWDAPGSRDFSEEDLRIYKRELERLRLSLKTVQNQPYDHLILALHYPPYSVT
GGPTGFTELIEEYRPDMVVYGHLHGADPNRLPQSWDGIPLHFVSADMIRFRPKLILETTG
EERDKP
>A0A720IMT9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Typhi str. 404ty|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHC
ANFTLDTIAPGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A418YAU9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Motilimonas pumila|TrEMBL
MTEQILQLATDKQGDLTLLQMTDTHLYSEPDGELLGVNTRDSFLAVMEAVLAQSQQYQAV
LATGDISQDHTEASYRVFTEQAKKLSAPCFWLPGNHDFQPALQTEFAAAGISACKHIISE
YWQLVLLDTQVVGVPHGQVSEQQLGFLKRALGQYPDKHALVLLHHHSVPAGCAWLDQHSL
KNADDLFAVLAQHDNANTLLCGHIHQTMDKQYQGVRLLATPSTCIQFKPNSDDFALDQQE
PGWRYLTLKANGEVDTQVHRLIDAGFVPDANATGY
>A0A0J1JJM5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium aquae|TrEMBL
MQNFTLPQANPDKVVLLQITDTHLFADESGSLLGVATKDSFHAVLDAVEASACPFEAIVA
TGDISQDHTEASYRRFCDGIARWSQPCFWLPGNHDYQPSMQAMLPSPQIKPCHQVLAGDH
WQVILLDSQVKGVPHGELNSEQLAMLDLALAAYPDRHALVLLHHHPLPAGSTWLDQHQLH
NAERFWQVVERHPQVNAVLCGHIHQALDRQYRGVRVLATPSTCIQFQPDSHDFSLDHQSP
GWRVLELLPDGSIQTQVHRVEGHQFTPHFDSAGY
>A0A7Z9D835|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurella multocida|TrEMBL
MFSTYTYDTSAEVFKFIQVTDPHLFREENSELLGVKTYQSFVQVLDEIKEQDFDYDFVLA
TGDLVQDNSDEGYLLFCEQVKRLDKTVFWIPGNHDFQPKMFAILNQNQGNLNAKKHIVLG
KYWQILMLDSQVFGVPHGELSQYQIDWLVSKLKDNPERYTLIVLHHHILPTNSAWLDQHN
LRNAHELAYALSPFDKVKGILHGHIHQEVDAEWNGYRVMATPATCIQFKPDNNTFALDCA
QPGWREIELYADGRIETRVKRIQKAQFLPNMNEEGY
>A0A2D4GV80|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micrurus corallinus|TrEMBL
MKEQNSCVGTGHPPMAGYGRMDPLELAVSPVKRLRTEYSFPYLFAEEAYQKLASETLEEL
DWCLDQLETLQTRHSVSEMASNKVGTPVCFHLSNIPPPHPAPSVLLCLALFSPFSDDSEG
KLTS
>A0A291DT89|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cedecea neteri|TrEMBL
MESLLTLPVADGGRIRILQITDTHLFAGKNETLLGINTWKSYQAVLTAILAEQRTCDLLV
ATGDLAQDHSVEAYQHFAEGISRISAPCVWLPGNHDFQPAMFNALQDAGISPAKRVYIGD
HWQILLLDSQVFGVPHGELSDFQLEWLERQLAAAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAAALDAVLKPWPQVKTLLCGHIHQELDLDWNGRRMLATPSTCVQFKPHCANFTLDTIE
PGWRWLDLYPDGSLTTEVCRLQSGKFSPDTDSEGY
>A0A5C0UBH9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter johnsonii|TrEMBL
MTLNNEKNWTIIQISDTHLMDQDHLEFVRINPEQSFHHVMQHIVERHPQIDAFVHTGDLA
QVPVPRTYQRYLDFMQSLKTPFYQVPGNHDNAEHFPFHQQQNKVHVIHFGPWSVVLLNSA
VKGKIDGWVDETQLNQLEQILQEFAQQHIVIACHHHPFEMQSKWIDQHKLKNTQDFTAVL
AKYHNVKIVLSGHVHQESWHEWHGIQFYSTPSTSVQFKPLSDHFALDEQAPGYRILQLNA
DGSHETHVERVLHAQQKINVEISGY
>A0A6C1MU32|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Halomonadaceae bacterium|TrEMBL
MDTPTQPLYLLQITDPHLKASEDGELMGMRTHDSLNAVLAHVRAHHPEPDGVLATGDLSQ
DGSLTSYKHFQARMGQFACPVYWLAGNHDNVAVMQRLIGGTPAAQKRLISHGWQLLFLDS
SVPDRVHGMLSDSELAFLDQSLAEYPDHHALVCLHHHPVPISARWMNAIGLRNPQALFDC
LAGHPQVRGLLWGHIHQQLDEVHRGLRLMATPSTCVQFRPGSEQFSLDDRPPGYRWLRLY
PDGHIDTAVERIAPGNFGLDLKSGGY
>A0A7K0DQN8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nocardia aurantia|TrEMBL
MTSVSSQHPEPEHFLLHISDTHFVGGRELLHGGVDSDANLRQVFDDFARSGARPEAIIFT
GDLADTGDADAYERLRAMVEPVAAELGAKVIWVMGNHDTRQTFRVGLLDEQPSDDPIDRV
HWVGGLRIIALDSTVLGHHYGEIDEAQLTWLAEELATPAPEGTILALHHPPVPSPIGLIG
LVELREQNRLAAILEGSDVRAILGGHLHYSTMSTFAGIPVSVASATCYTQDLNVVFPAAR
GQDGGQSFNLVHVYGDRVLHSVVPVGDFPTLYEMPADQIAAFLALSQEEQTAAMTAASPR
>A0A6G6PMP7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia sp. 1701011|TrEMBL
MDSQLEVTAKNSKIVRILQVTDTHLFANTENTLLGVNTYRSYQAVLDAITEQNLPIDLIV
ATGDLVQDQSPQAYQHFADGIARIPAPCVWLPGNHDYPPAMVETLRVAGISSAKQILIGD
EWQILMLDSQLQDVPHGELSEQQLEWMKASLDAEPERTTLIMLHHHPLASGCTWLDQHSL
RNSHILADYLKNYPNVKAMLCGHIHQEMDENWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELSINEQSQRHITTHVHRLDTREFSPDLDSDGY
>A0A550GDD9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. ALS1279|TrEMBL
MPSLPTQSTDSSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIERVLQEQPQIDLILAT
GDLSQDGSEASYQRFRQLTSAIDAPTRWLAGNHDEIPPMQAACQGSELLEPVIDLGAWRI
VLLDSSIPGAVPGFLADSQLELLERALSEAPQRHHLICLHHHPVSIGCKWMEPIGLRNPD
ALFAVLDRYPQARTVLWGHIHQEFDQQRGNLRLLASPSTCVQFAPGSEEFRVDSEAPGYR
WLRLHADGKLDTGVSRVTGIHFEVDYSVKGY
>A0A6I6EIU1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia sp. J780|TrEMBL
MDSLLKLPVASGSRVRILQITDTHLFAGKHETLLGVDTWASFDAVLDAIAAQQRHYDLIV
ATGDLAQDHSIEAYQHFAEGIARLPAPCVWLPGNHDFQPAMFTTLAASSIADQKQVLVGD
HWQIVLLDSQVFGVPHGELSDYQLEWLECALAAEPQRHTLVLLHHHPVPSGCSWLDQHSL
RNPHMLDVVLQRYPLAKTLLCGHIHQELDLDWQGRRVLASPSTCVQFKPHCTNFTIDAEP
PGWRWLDLYDDGRLETQVQRLATRMFNPDLDSEGY
>A0A291TZP4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sp. CA23|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDAPLMTEYLHAAGISEAKQLVGEHWQ
VIMLDTQVRGKPHGVLGDHQLAALDSALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDETHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRVASQVWRLPVGQFVPDPDATGY
>A0A852PXW8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNAFVYQTEKPVIKLLQITDPHLFKDENAELLGVNTQASFTQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQAVLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLVPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTQVKRIQQAEFFPNMQEEGY
>A0A8D4UF16|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLGKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELYSDGSIRTEVKRIQQAEFLPNMQEDGY
>A0A672SNI6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sinocyclocheilus grahami|TrEMBL
MLNRELTHLSEMSRSGNQVSEFISNTFLDKQHDVEMPSPQTQKEKEKKKKPMCQISGVKK
LMHSTSLTNSNIPRFGVKTDTEDSLAKELEDINKWGLNVFKVTEFSGNRPLTVMMYTIFQ
ERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTD
LEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCD
IFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRI
QVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEK
SQFFHRYIRIYLNFLSFSSNIYILFYFNY
>D0IM51|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. RC586|TrEMBL
MKVSSQSAGSSIKLIQITDTHLFAPEEGSLLSVNTSDSFAAVVAAIGEEMVEFDAVLATG
DISQDHTPESYQRFVAGIQPLHKACFWLPGNHDYKPSMDSVFPASQIHATEHVLLGEHWQ
MVLLDSQVVGVPHGKLSQQQLELLDSKLAEYSGRHTLVLLHHHPLLVGSAWLDQHSLKES
ERFWDVVAQHCNVKAILCGHVHQEMDRLHLGARVMATPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A811H1G3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter mucicolens|TrEMBL
MSHVFHVITAFIALYVIWRFVWRLRWPAAGKVLLSALVLLAAEHHLITRTFFGTMASPEV
PAAVLMALGWAFGALILLAVFLFVSDVAGLAVSLFSRRRGRALLGCPRLRAVSAVAALAL
SALGVWQAVRVPQVETIEVALPNLPRAYDGFRIVHLTDLHASRLLQRDWMQAVVARANAL
EPDLTLITGDLVDGTPAARAADVQPLADLRAPHGVVAIPGNHEYYAEYLGWLQAFEKLGL
RMLLNEHMVLDRDGQPLVLAGITDSVAARVGQPLPDIDAAMKGVPPSSAVILLSHRPVGA
KRHAQAGAGLQLSGHTHGGQILGPHFITQLVNEGYVSGMYQVGGMQLYVSNGAGLWPGFP
IRLGRPSEITQIVLRAAPPA
>A0A1D8I3J9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter ruhlandii|TrEMBL
MLIAQITDLHMRTPGDKAYGIIDPAAFLGPAVRALNALTPRPDCVLITGDLTDLGRPHEY
QALRDQLQALEIPYFLLPGNHDDRAQLRAAFPDHGYLQGQGPFIQYAVETYPLRLLALDT
VVPMKSHGELCDERLGWLAARLAEQPDRPTLVLMHHPPFQTGIEHMDDIGLLAGGPELER
IVARYPRVERVLCGHLHRTIFRRFGGTIASTCPGTAHQLALELGPRPTLQYIMEPPGYQL
HWWHDGALVTHHAVIGEYPGPYPFA
>A0A4P7XFW1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hydrocarboniclastica marina|TrEMBL
MNTSGRALRILQITDCHLGRTGHSSLLGMDTRASFDSVLELVKQNYPEPDLVLATGDIGQ
DGSVEAYRYFQDKMSVFSCPVFWFAGNHDNFPAMLEVAGSRGALEKTFASGPWQLIFLNS
AVPGKVHGFLRPKELSLLNRTLEATPDKFALIAFHHHPIDTDCQWLNPIGLRNREAFFAT
IDRYPQVRGVVWGHVHQEMDQRRGDVRLLAAPSTCIQFEPRSREFGVGRESPGYRWLELH
PDGRIETGVVRADHIEFEVDMNSGGY
>A0A093T4Z1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Phalacrocorax carbo|TrEMBL
QNIFWQMRMTHSMCFVHSFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLY
RSDSDYDLSPKTMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLL
>A0A7D4HQK6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter pestifer|TrEMBL
MARIHSLTRRDDAPAMLVQLTDSHLFGEPETSMLGVNTDASLRAVLRQIEADGKHPDLLL
ATGDMSQDGEAEAYRRLARVLSEAPALERASIRCLPGNHDLPAVMRQELPQWSVPVTDVG
AWRVVALDTTVPGSNAGHLPASQLDLLEAALAETPGRHTLIAMHHNPMQIDSHWHDSMMI
DNPQALFKLLTRWPQVRVLLWGHVHHEFDRRRHNLRLLATPSTCFQFSIRDGKHVVDNMA
PGYRWIKLYQDGSMATGVRRVQDALWHGARTAADNAQAA
>A0A0S7F8L0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
EVARNMQKDDRSGDDSQRESVSDESSDSPEPEPVTCMEPFMVRRLSCRTVQLPPLAFRQA
EQYYCDRKPEPDTVTVPPRPTTLPLRAPPLIAITSADNTSFDVDNGTSSGRSPLDPMASP
GSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLAS
LRTVRNNFGALTNLQQDRASNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQL
ETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSESSSMSEE
>A0A0S7FEG3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
MAQQGGTGVAHQDTLAVPPMPKHSGLNEDLVKILRENLLQPERPRGHRRSPSSISPRLSP
RNSPRLLRRMLLNNNIHKQRRFTVAHTCFDVDNGTSSGRSPLDPMASPGSGLILQANFVH
SQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALT
NLQQDRASNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSESSSMSEE
>A0A0S7GZA6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
MIVTPFAQVLASLRTVRSNFALITGQQDRAASKTRSSGSNPPSMCKTSLAEEPHQQLAIE
TLDELDWCLDQLDTLKTRNSVSEMASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLE
KPDDMDIMSPTTKEKDKKKHPMSQISGVKKATHSLVPSTIPRFGVNVSQEEFLAKELEDI
DRWGLDIFKVAEYSGKRPLTVTMYTIFQERDLLKTFKIPADHFINFTEPYVSVI
>A0A3M0JUX3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hirundo rustica rustica|TrEMBL
MGALALPVSPVKLLRTERAFPCLFAEEAYQKLASETMEELDWCLDQLETLQTRHSVSEMA
SNKVSAIYY
>A0A0S7HIB1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
MGLCCSEKQKRNFEMSSSWQKFKRMLNRELNHLSEMSRSGNQVSEYISNTFLDKQNELEL
PCPVQKVRKRKQNQQQQQQQVGMMTQISGVKKVNHTSSILGNVGNRFGVKTDQEELLSKD
LEDINKWGLNIFKVTEHSHNRPLTCVMYKIFQVSFCLLLEG
>A0A6V8LSP7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Desulfovibrio sp. FSS-1|TrEMBL
MELPRIEARGLFVVCDPHVAASPPGHRLEGYREQVLAKLSACLDRARELECHPVIPGDLF
HWPRENPNSLLVELIELFRPQRPTVLPGNHDKYLARFTPDVSLAVLAAAGAVRLADRPGP
AFRLETPSGSVLVGASPDGTPLPRHVERAGAVETVWFSHHSVGFPDFQEGLVAPRPIEGL
DWLINGHIHRPQPMVVKGGTRWCNPGNVTRLTFTARTRERVPSAWVWRPGAGELERWPVP
MRPFAEVFPDQPFPAEPTAEESRSLFLKGLERLALRRTQEGLGLKDFLDANLNPEDPGTG
LIWELYEEVAGGEKRPRRS
>A0A345VL57|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptococcus pluranimalium|TrEMBL
MTTLAFMSDLHIDVNNFTDYETKTLIDFLKEEGVDHLHIAGDISNHHYQVSLPFLETLQQ
HVSLTYNLGNHDMLDLTETDIKHLDFKIHEINTKKFLAFHGWYDYSFHPEKTEEQNLAFK
NQFWFDRRLDRHASDSKLTEETLSRLDDTLTHYPEIDLVSMHFVPHQNFLMTHPKFIPFN
AFLGSQAFHDVFVKHHIKDVIFGHAHRSYGSQMIDGINYHSRPLGYRREWDLTIDYVNQH
PELNPTGTWNLSKRYHLVKRLPDYQNYTKKQLKEEFRKSVTVFDF
>A0A4Z1CF33|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter confluentis|TrEMBL
MTENDHQLPLRVLQITDPHLMADPAGALLGVNTRDSLAAVIDKVLQDHGQPDLILATGDI
AQDASEEAYRFFGEKLEVFDCESVWIAGNHDDSRVLTRIATELNTSSRHVITGGWQFVLL
DSSVPGKVHGELAESELEFLEKTLTENPDQPAMVALHHHPVDIDARWMSTIGLRNNDDFW
RIVDRFPQVKTVLWGHIHQVYDEYRKGVRLLATPSTCIQFTAGSEKFSVEEKSPGYRWFE
MMPNGEFSTEVKRSEDFTFELDMNSTGY
>A0A5R1QT15|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. BCA14|TrEMBL
MPSVSTVNPDAPALLVQLSDSHLFAEANGTLLGMNTRESLQRVIELVRAQQPQIDLMLAT
GDLSQDGTLESYQQFRDMTRQVDAPARWIPGNHDEPQVMALAAMHSDLLEPVFDIGNWRV
TLLDSAVPGSVPGYLQDRQLQVLAQALSEAPSRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDHERNGVRLLASPSTCIQFAPGSEEFQVSEQAPGYR
WLRLHADGRLETGVERIKGFTFTVDYGSNGY
>A0A066URP7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio fortis|TrEMBL
MELSHTSKLDESSIKLVQLTDTHLFAPSNGSLLSINTEDSFRAVVDGIVNQGYEYEAVLA
TGDISQDHSAESYQKFEAGIQPLEKPCYWLPGNHDYKPNMGSVIPSAQIQCVEHVLLGEH
WQMILLDSQVVGVPHGRLSDQQLDLLEQKLAEYPQKHTLVLLHHHPLLVGSAWLDQHSLK
DADQFWDVVSQHSNVRGVLCGHVHQDMNREHLGVQVMATPSTCVQFKPNSDDFALDTLSP
GWRELELKPNGEITTEVRRLERGAFAPDFNAEGY
>A0A731XT76|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. VII serovar 40:z4,z24:[z39]|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A826WYF3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEATVRILQITDTHLFAQKHETLLGVNTWESYQAVLEAIHAQQHEYDLIV
ATGDLAQDQTSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
HWQILLLDSQVFGVPHGELSDFQLEWLEKKLADAPQRHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLANFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTQVHRLSDTRFQPDTASEGY
>A0A4U2DB02|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. F13|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVNQGFDYEAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVDHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLIELPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPNGQFLPDFEAGGY
>A0A3E1UXU5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MPQTDQSRLVHVVQLTDAHLFADPAGSMLGLNTRDSLRHVVAQVRREQPLVDLLLCTGDL
SQDASVASYEAFRELTAPFAVPTRWLPGNHDEARVMAQVAPELVQAVTDIGAWRIVMLNT
AVPGATHGLLEDDQLAVLEAALREAGERHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDI
VEGYPQVRALLWGHVHQEWDEVRDGLRLLATPSTCIQFAARSEDFQVSEEQPGYRWLRLH
ADGRLETGVERALDFEVKLDFDSPGY
>A0A8C5YLJ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marmota marmota marmota|TrEMBL
MLNRELTHLSESSRSGNQVSEYISRTFLDQQTEVELPRAAPEESQRPMSEISGLRGLPHS
ASLSAATVPRFGVQTDEEGQLAKELEDTNRWGLDVFKVAELSGNRPLTAIIFSIFQERDL
LKTFQIPADTLATYLLTLEGHYHADVAYHNSLHAADVAQSAHVLLATPALEAVFTDLEVL
AAIFASAIHDVDHPGVSNQFLINTSESGVGGDTRGRGRRLQG
>A0A524BUI7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MSPPDQSRPVHVVQLTDAHLFADPAGSMLGLKTRDSLRHVVAQVRREQPLVDLLLCTGDL
SQDASVASYEAFRELTAPFGVPTRWLPGNHDEAQVMAQVAPELVQAVTDIGAWRVVMLNT
AVQGATHGFLQDDQLAVLEAALKEAGERHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDI
VEGYPQVRALLWGHVHQEWDEVREGRRLLATPSTCIQFAARSEDFQVSEEHPGYRWLRLH
ADGRLETGVERALDFEVKLDFDSPGY
>A0A7R9CPQ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Timema poppense|TrEMBL
IFLETSSLGICMNELLTLEKSDVIPRANLAATQAFHLALNKCNELVHITNHEHTIEFVNQ
AAEYHMGFPRSAMVGKNLMEMCRLEVNELMVQELQKGREWEGVITWYTRTGERLILSGRV
LPFSLPGRPPSLYVYVHESPTMSEKRSSQSIIPFSQQGFQASAAQRGSITSAGTRRQSLA
KLYNLQIQAPITRIIELINSAQEEAAEPVVQILDKVIDIVRTTELYTPHMKERPIKLTDP
VTSDLISALLMVRTSLHLGETLIPIKAGSGPRYSRGSRLICILLGAFGKQQGGTGTTASL
TRRSSSESSAFKNPLSIPGSAKGTMYLAGSSKMKDLLDTALNWDFDIFSVEQISEKRPLV
HVGMSLFLHFESHLALGCDESTLKNWLTIIELNYHSTNSYHNSSHGADVMQAAAGFLKTD
RLMQTLDSLDRAICLIAAAAHDVDHPGKSSAFLCNSDSDLSLLYNDLSVLESHHAALTFK
LTMSDERVNIFKGLERDTYKVVRQNIIDMILATEMTRHFEHLAKFVNVFCKGGIQDEENA
EAKADQMDMLAYSPENMSLIKRMLIKCADVSNPTRPIASCVEWALRIAEEYFNQTDEEKA
NNLPVVMPLFDRSTCSIPKSQIGFMEFIIRDMFEAWEAFIEMPELLQYMERNYIFWKDLE
ERGISSIQDIIKNQRIGETCH
>A0A741MZZ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. arizonae serovar 41:z4,z23:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYGALQEAGISPAKHVLIGE
EWQILLLDSQVFGVPHGELSEFQLEWLERKLANAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSLLAHFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A808XGV8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Raoultella sp. X13|TrEMBL
MESLLNLPLAGETRVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRPCDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
RWQILLLDSQVFGVPHGELSEFQLEWLEQKLAEEPERYTLLLLHHHPLPSGCSWLDQHSL
RNAGALDRALAAFPRVKHLLCGHIHQELDLNWNGRRMMATPSTCVQFKPHCANFTLDTIS
PGWRWLELHADGTLTTEVCRLNGVKFHPDIASEGY
>A0A4Y2FH12|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Araneus ventricosus|TrEMBL
MVNLIQWNARGLRNKALAKDSFLKADIVAIQETFLTPSVNFALPNKILYRTDRHNSPSGG
LLIGINKTFSSHLVNLQLPPSEVEVQAVRIIIESKPILIINVYSPHGNFESSFLENLYAS
LSPPFLIVGDFNIHHPILGSSRTSRSANVVLDWISTHNMCILNTSNPTYFKQGCHPSLLD
LSICSPDLLYETKWTVYNDTFDSDHCPVEISFNYGNSKGPSVRRRIHWGKFGTSLNSILD
RENDIHSIQSFEKLCNQEKNNNTLIQDMFSKKFPPWWSSECSYLLGQKRKFLRLAKQSRY
NPYWNRAKHIAAKLRKLIIHLKRSYWDKLCDNAGSSKTSFRIIRSLRSRDMPQQNAHRLI
ILEGSNLTSPLGQANAFGSMFGSSPISEGIPLDFSGSATPMDSEFSIRELLQSLPKKLNG
SPGSDGITGRMLRCLTLVNLKKILSLVNKIWLSGNIPPSWKHSVIIPILKLGKNASELKS
YRPISLTSVLCKTTERMICRRLTDFFLKENIFHPHHFGFLPFRSCESLQMMFFNTLLKAR
SNKEYIIAASLDISSAYDSVWPDGVVYKALQIGLSGHTARWIHEFLTNRTLQVRWSGKLS
ASFTSNRGVPQGCCISPYLFTIYLHDVFEIIPPGVTCLIYADDIFIICSDPSLQNVKTKL
QITIQKIQIWCQNWKLKLDPTKSTVVNFSNKRQTPNFQISVDNVYIPWSNNMKVLGIFFS
ANLSFNCHFNYVAKKALKRLGYLRALGGSNWGANTVHLLRLVNACIRSICEFGAHVTSYA
GSTSWRKLEVVHHNCLRFAAGLPRWTPIPVMFAETGEIRLRDRSLALSISFFLRHFALGD
NFSPIKKSNLCTLDGLRPSFKERFSGGTNWLNFLKDANVRIENFIPFVYPVELQQENTIS
FHTNDLPFQQSQIPYPTLCKLFDEYVNKEWNSSILIATDASKGEEGVSLAALNITYNRTL
TLKLHPMNSVFTAEGCAILIAIERFIQEADKSYILCSDSLSVLKSLESLHRKSPTISLQI
GSAIIRAIPRSTAIKLVWVPAHVGITINEQADEAAKAARISDVNIYPCISTEDLRKVIFR
VKADQGRIQWESTKYFPSFSHLPKTTKTPLLPRRKEILLTRLRTRSLPTKAILFKVGLES
SPLCRQCGIVDSNDHLLLSCTVFEQLRNNLRASLGIGALHYNWICTISTFNRRACSAALL
VFSKDDAQSDALKWAAEKLSCECTMAYTPEDATESYQNTHPHLVFIDSRQSKTFDYTALC
RAIHSIQGSQYSCLVAVVKKSAVDKEDGSIVSFLRSGFTRWFVENHNLGVCLNELIQIHH
TDISYLLKLRASQALFSALDSCREGIIVTNLDHNIQYANKASEKLLGYTAEDLCGKDAQT
LCRAESVKADIAESINMQVKKGKDWEGTLFHKRKSGENLPLWSRIQPVEIYSGQAEHLIH
VNECPFNEKPFSTETDLLPFVKAPRKGSCDVRSFSGETGLNRRQSFAKFHPMTLEPPITK
VINMILATQEHSPLFVVQALDRVLDILRSTDIYSPQFTGLRQNHADDQVASDLFSGLISN
SKQVIRRFSHEAFKASKSVLGVPSSGTTQPPPLTPSTVPTLANAPPRVKELLENVTEWHF
DIIELERVTEKRPLIWVGMSIFATFNACNLLNCDESVLRNWLSLMESHYHANPYHNSTHA
ADVLQATAYFLQKPRLKAIFDPIDEVVSLIAAAIHDVDHPGRNSAFLCNTGSELAILYND
LSVLESHHSALAFKLTIGNEKVNIFHNLNKDTYKEMRRSIIDMVLATEMTKHFEHLSKFV
NVFTKSVEAEEDESLEPSSPDLSAMSTPENIVLVKRILIKCADVSNPARPLNSCKEWANR
IAEEYMSQTDEEKSKSLPIVMPAFDRTKCSIPKSQMGFTDYFVNDMFDAWDAFCDVPELM
ENIKTNYEYWKQQEVLRQKGIEAQESTSNT
>A0A646NXS2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas haemolytica|TrEMBL
MPSVSNVNPDASALLVQLSDSHLFAEADTTLLGMNTRASLQRVIELVREQQPQVDLVLAT
GDLSQDGTLESYQQFRDMTRSIGAPARWIPGNHDEPQVMAQAAVHSDLLEPVVDIGNWRI
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPSRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRALLWGHVHQEIDSERNGVRLLASPSTCIQFAPDSEDFQVSEQAPGYR
WLRLHADGRLETGVERVEGFAFTVDYGSNGY
>A0A1I8MIV0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Musca domestica|TrEMBL
MRNCFTKITNVFRKQARHKSSEEGSLQQEDDDVYTRKKTTNTEPTVANIETAKKSTLSGC
LSLKTNDKHSGWDRRDGVGDNSEVAHTLNLSTQSIMDGDYEKHLQLRLSQRSSQSTMNEA
KNDYNRRDALHANDGVYQQKQLRLLGRNVDEAEKGQLLYMEATPSPVSFAIDASPTNGSR
RSFVADNKTNAMPTNYDKCNSNVAKTPEEMEYEAKVAAEFEDVMTPLPTTAKHIQFAFGR
NLRPEIAEVIRSLDANALRINNLTVEDKFELLRRFDCAQQARRHGRGNNFVRSMPPPGHS
IQIDLGLVGHEPDDPEDNPSDSSTEGVVLRRKHHQTPKEKSTSCLYERRLPKSPKLKLIL
ESKWKETSNGSKTGIAFKEVNDNDIERNAYDVKYPTVLPPNPQLKALLVFYKSDNICEVV
QQACNRQQLEISLVKTKETAFENLCSATECFHVIIIDARSPKHLDAEHIARSIRHMSGHH
FTTIIAVVKKSMFERDDVINALLDAGVNRCMAESTSLSMCAMELKQILHSIVRPHNVIST
QQALYTALHRLKEVLIITDDLLRIQYANRSAERLLNMRLDEVISKPLADIFISDVSTINS
SVQGKGIREFDGILTVKRKNQEGIPMHVRVVPVACIGRTPTHFVFNFDVPGGQMDFIATL
PQPKEAPRGSLHSIRRGSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQENC
SAEEARLIDKVMEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPNVYSSRRSSNDSIV
RTNCSNRQSTIMPAKMKATPLIMEILEESLNWEFNIFKLEEITENHPLLYLGMEIFRRFD
VFATLNVDENVCKNWLAIIERNYHADNSYHNSTHAADVMQATGVFISQLAAKDLVMDRLE
EASALIAAAAHDVDHPGRSSAFLCNSNSPLAILYNDLTVLESHHASTTFRLTLGDDNANI
FKNLDTDTYKVARTTIIDMILATEMTRHFEHLAKFVSVFGTEMEPRDIVQSEEESSVLMR
RMLIKVADVSNPARPMICCIEWSRRIAEEYFTQTDEEKAKNLPIVMPMFDRGTCSIPKSQ
IGFIEYIIQDMMHAWDSFIDMPELITYMQINYSQWKKFEEQGIHTLAEVKAKQMSLMNKK
SALK
>W1DFM3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pneumoniae IS43|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A2K1QBM5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mixta theicola|TrEMBL
MDSLLKLPVVSGANIRILQITDTHLFSGRHETLLGVNTWASFNAVLEAIEAEQRPIDLII
ATGDLAQDHSPEAYQHFAEGIARLPAPCVWLPGNHDFQPTMYDTLAQSGIAEAKQVLLGE
RWQLVLLDSQVAGVPHGMLSDYQLDWLEKTLAQSAERHTLVLLHHHPLPSGCSWLDQHSL
RNSHALDAVLQSYPQAKTLICGHIHQEMDVDWHGRRLLATPSTCVQFKPHCTNFTIDAVA
PGWRWLELDDSGAVQTQVQRLSTRAFTPNLDSEGY
>A0A7J6A4S6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ameiurus melas|TrEMBL
MYITFSSFEGENGPSPGRSPMDLQASPGLVLHPSFPQSGRRESFLYRSDSDYDMSPKTMS
RNSSINSEGHAEDLIVTPFAQVLASLRTVRSNFTILANVTSPTDNVFPTSRGHASAMKLT
ISLFLSTGGRQLRANLQFHKQRSLALLPGQNELYHRTQWNHMGNRGLEAYQTL
>A0A0H3DMA0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Edwardsiella tarda (strain FL6-60)|TrEMBL
MESLFHLAVASGAPVRILQITDTHLFAGQQETLLGVNTYRSYQAVLAAIRAEAHPFDLIV
ATGDLAQDHSAAAYQHFAAGVAALHRPCLWLPGNHDFQPAMVDALAQAGVHANKRALLGD
RWQIVLLDSQVVGVPHGELSDYQLEWLEQTLASEPQRHTMLLLHHHPLPSGCTWLDQHSL
RNAHALDEILRRYPQVNTLVCGHIHQELDLDWNGCRLLATPSTCVQFKPLCTNFTIDTIS
PGWRYLTLYPDGRVTTAVHRLASSEFRPDLDADGY
>A0A1N6MT09|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus innexi|TrEMBL
MESLLEIPVVKNTTARILQITDMHLFANQGGSLLGINTYRSYHAVLDAILEQNIDIDLVV
ATGDLVQDQTSGAYQNFVDGVARLPAPCVWLPGNHDYQPTMVDVLAAGGISPSKQIFIGQ
HWQLIMLDSQVQGVPHGELTEYQLEWMKKCLDEHSDRQAIVMLHHHPVPSGCTWLDQHSL
RNSPALAEFLKGKSQVKTILCGHIHQELDVMWNGIRVIATPSTCVQFKPHCTNFMLDTVA
PGWRYLELPVAGDEEATLQTQLYRLESNEFCPDLDSDGY
>A0A418RS02|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylococcales bacterium|TrEMBL
MTCLSILQITDLHIQPNLDDHFLGINTEDYFHRVLDLAFSKEQAIDLILLTGDLAQDPCP
ASYQRILDRIYASNTPCICLPGNHDDFALMQQVFNTPKITCQKQTVFENWQLICLNSQII
GAPGGRLLPEELQFLEGCLKSNPDHHALIAVHHHCIATNSTWLDMMQIENSSEFLTILES
YPQVKAITTGHIHQEKDDLNKTIRVFGTPSTCFQFTPNSHHFSLDNTMPGYRVIKLYETG
EIESEVTRLPGTLTELQIESSGY
>A0A2S9IDE7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea coffeiphila|TrEMBL
MDSLLKLPVASGSSIRILQITDTHLFAGKHETLLGVNTWASYEAVLEAIAAQRRHYDLIV
ATGDLAQDHTTEAYQHFAEGIARLPAPCVWLPGNHDFQPTMFSTLANASIADEKHVLIGD
CWQVVLLDSQVFGVPHGELSEYQLEWLDKTLAKEPHRNTLVLLHHHPLPSGCTWLDQHGL
RNPHMLDAVLQRYPLAKTLLCGHIHQELDLEWQGRRVLASPSTCVQFKPHCTNFTIDAES
PGWRWLNLFDDGRVETEVCRLTTRIFSPDLDSEGY
>A0A7U8W162|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli FVEC1412|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A2L2JFJ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. SGAir0187|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGD
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLTGAQFRPDTASEGY
>A0A5Z5HUC7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella infantis|TrEMBL
MFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIVATGDLAQDQSAAAYQHFAEGIASF
RAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGEQWQILLLDSQVFGVPHGELSEFQL
EWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSLRNAGELDSVLANFPRVKYLLCGHI
HQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIAPGWRTLELRANGVLETEVHRLQDT
RFRPDTASEGY
>A0A7Y7SF65|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas yamanorum|TrEMBL
MPSVSALNPDASALLVQLSDSHLFAEAEGGLLGMKTRESLQRVIELVLAQQPQIDLVLAT
GDLSQDGTLESYQAFRDMTRQIEAPARWIPGNHDEPQVMLQAAINSALLEPVVDVGNWRI
TLLDSAVPGSVPGYLQDQQLQLLAQSLSEAPTRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERVQGFAFQVDYGSNGY
>A0A399EZ23|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Calidithermus terrae|TrEMBL
MDAIRGIEPGRARQCVLLVTGDVAFSGKPEEYRLASDFLAGLRQRLESETDNPVEVILIP
GNHDCDFAFDSKARGLLRDASLNCGDADASVVDIATNVQSAFFEFRSTFAKGACPQGLER
LFQTVEIPVAGGRLYVNAYNTAWLSTLSEKPGELFMPVTRLTPPDQRDGLVVSVFHHPYG
WLEPNNARDFRNLIERTSDFALTGHEHVPGVRDVSNRDGSTQHYIEGGVLQDNDDPAQSW
FHVIVLDLLNNQHKTVTLTWNGERYSTSCEDAWSSIPWNSLRQRREFQFQQGYAEELDHS
DFRFSTARRQFSLSDLFLYPELTVSSPRDQARRIDPKLGKPEATRVRSGQFLDFIREHRK
VMLYGPEKSGKTTLSKRLQVELYEAGMVPVRLDVSRLKDLQPV
>A0A2H6AU33|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR39|TrEMBL
MVILESALAVAALGGVWAFGVEPRRLMVRRFSVPWPGVPGSRLRIGVLSDLHAARPHMGE
GRIRRIVARLLAEDPDLVLLPGDFVATGTVGVAPLAPERIARALAPLARGRPVFAVLGNH
DWDLGGEPVAAALEEVEIRVLRNEHLRLPTPFGELVLAGVDDPVTRRDDLARALAGTEPD
EPVLLLAHAPDIHTAAPEQVRLLIAGHTHGGQVRLPGLPPPVTLSRLPRRQAHGLHHDRG
RHLLVTAGVGTTGLPLRFARPPELVVLDLVGDGTRGAVAAAEPVADPA
>A0A2K6DDD0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Macaca nemestrina|TrEMBL
MEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAEPERP
PHRPIERADAMDTSDRPGLRTTRMSWPSSFHGTGTGSSGAGGGSSRRFEAENGPTPPPGR
SPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
FAQVLASLRSVRSNFSLLTNVPVPTNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
PSPTMKEREKQQALRPRPSQPPPPPVPHLQPMSQITGVKKLMHSNSLNNSNIPRFGVKTD
QEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYML
TLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDSELALMYNDESVLENHHLAVGFKLL
QEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLD
NYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKH
TASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEE
SRGPGHPPPPDKFQFELTLEEEEEEEISMAPIPCTAQEALTAQGLSGAEEALDTTVAREA
SPAQESLDVMAQDESLEAELEEVYLTQQAQSTGSAPVAQDEFSSQEESVVAVSQSSLSSL
ALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACTGTSGEDTSALP
APGGGGSGGDPT
>A0A2K6DDB0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Macaca nemestrina|TrEMBL
MKRSRSALSVAGTGDERPRENPESGHANMLGADLRRPRRRLSSGPGLGWAQPETSDPRVP
LPPRPTTLPLRIPPRISITRAENDSFEAENGPTPPPGRSPLDSQASPGLVLHAGAATSQR
RESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVP
VPTNKRSPLGGPTPVCKATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKF
KRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQALRPRPSQPP
PPPVPHLQPMSQITGVKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCV
SDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVL
QSTHVLLATPALDSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKM
VIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPT
KPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWET
WADLVHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPPPDKFQFELTLEEE
EEEEISMAPIPCTAQEALTAQGLSGAEEALDTTVAREASPAQESLDVMAQDESLEAELEE
VYLTQQAQSTGSAPVAQDEFSSQEESVVAVSQSSLSSLALQSPLLPAWRTLSVSEHAPGL
PGLPSTAAEVEAQREHQAAKRACSACTGTSGEDTSALPAPGGGGSGGDPT
>A0A7X5TFP1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chlamydiae bacterium|TrEMBL
MELNSNNIKPSFHVSDLLWDLWCVVSIIGIWPRFIEPNLVTTTKLSLPISNLPEELKDLR
ILQFSDLHLHPRVPDFFLTKLISKARKLKPDLIVFTGDFLCYSLLSEAERLKKFLNSFSA
PYGCFAILGNHDYQQCVSVNEKGDYDVIRNDTSLIYKGFQRLFSPLPLSKKVTPETQSIE
HHQQLMHLLKETPFKLLDNATAVIPIHGTKLNLCGVGEHMLGHCKPEKAFQGYDKNYPGI
ILAHNPDCVPQLQQYPGDVILSGHTHGGQVNLPLMWRKFILIKNIQFKRGLVKAGKKWVY
VNRGIGSVFPFRWFSVPEILLLTLE
>A0A549VJT8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter youngae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQCVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRIFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVCRLQGNRFHPDTASEGY
>A0A0A3B818|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chelonobacter oris|TrEMBL
MKTTFLHHSDGIPVRFIQVTDPHLFADKKSALLGINTYDSFVAVLSEIQKTAFDFEFVLA
TGDLVQDSSSEGYRYFSEEIQTLQKPVFWIPGNHDYQPHMVEMLSRHTQYISPLKHIVIN
DTWQILMLDSQVINSPHGYLNLYQLDWLLAKLEQYPNLYTVIVLHHHIAPTRSAWLDQHN
LRNTSEFLSCLAQHRHIKAVVSGHIHQEMDTVWNQYRILTTPSTCIQFKSDSYHFSLGSM
PPGWREFELYPDGTLKTQVRRIENNLFTPDFNISGY
>A0A1B7JYZ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia heimbachae ATCC 35613|TrEMBL
MDSQLEVTAKNSNVVRILQVTDTHLFADTEKTLLGINTYRSYQAVLDAIIEQNLPIDLIV
ATGDLVQDQSPKAYQHFAEGIERIPAPCVWLPGNHDYPPAMVESLRVAGISCAKQILIGD
EWQVLMLDSQLQDVPHGELSEQQLEWMKHCLDNQPERATLVMLHHHPLPSGCTWLDQHSL
RNSHILADYLKPYTNVKAMLCGHIHQEMDELWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELSVNSQGEKQVNTIVHRLNTREFSPDLDSDGY
>A0A0H5LZ57|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia intermedia|TrEMBL
MESLFKLPMASGAKVRILQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGIARLPAPCLWLPGNHDFQPAMVDALADAGIAPSKQVLVGD
NWQILLLDSQVFGVPYGELSDYQLAWMERCLVAYPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTIDTVA
PGWRYLDLLPNGILETEVRRLASDEFSPDMDADGY
>A0A5W2A9J0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Pretoria|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A6P4IMF6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila kikkawai|TrEMBL
MGCSPSTLPAPNAAGGGGVGGAPGGQGSLPLDATEKDGSRLFCIKLRRSRLRRCSCGGVT
LQVPNDGNGSTAGSGTGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHS
VVRRATGSTGTSGTSSSGGGNSHRHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPN
PQLKALLVFHKADSICEAVTAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDA
RSAKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLA
MCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLNMR
LDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAP
THLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSL
PLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIG
ALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKANPIIMELLEESLSWDFDIFKLE
EITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVMEAHYRKSNTYHNSTHAADVMQ
ATGAFITQLTNKDMLVMDRMDEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTV
LENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVF
GGEEPREQHSQTEEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQ
RHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYD
EQGVNTLADIMAKQPPVGKMANSK
>A0A329HMJ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. RIT 418|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSAPCVWLPGNHDFQPAMFSSLHDAGISAAKCVFVGK
QWQILLLDSQVYGVPHGELSEYQLDWLEKRLSAEPARHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLVKYPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLSGSQFRPDTASEGY
>A0A5E4L901|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKLLVLADIHGDEVVLEKLQAHRKDAYDYVLVAGDSTNNSTSFMADLIETFPNAYMIPGN
NESANVLEIMHRAKHYAHEKRFELKEGYNVAGFGFSNPTPFHTPGELKDDEIYQKLSKMK
IDGKTILLLHAPPYGLLDEIKGNHVGSQAIRKIIEEKQPYMVFCGHLHEVIGIERLGKTL
IVNVPAAENGRFCTAELTNSTVCVQFKEI
>A0A508SSJ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bradyrhizobium ivorense|TrEMBL
MPTRIAHLSDLHYGGAFDLATWRAVEKAVESFDPDLIIVSGDLVDDPRRDHLLAAKKELE
DLAARAKAELYVVPGNHDVFFSGVDLEGTRSGWYYETFGGVELPVGAIGGGQAAAGTAAQ
NVGFTRQGGRWQVIKDRISVLLGLGPHANPSPLAPPPAPDGAYASMLREPNKAGVLLALI
DSNAADQPIRIATGSVSRDHLVALDAELTSLNARLEADSLAHFARIAVIHHHVLPIAYTA
GGIIGAEPFMVLHNAGDVLGLLAKHQFDLVLHGHKHRAQFARIDLLPDSPEGYPIAIAAA
GSAALLTPNNPTGNSFNLITIQDNGRIVVEALYYGAGSAPNRGGRKGEAVKAYTEGLDST
KRRAFMRACQRYPIYCHERIYHFEISELGDFTLHHHTVGLRALRQNGEYRKRPHSIRIPA
FGQLARGLQLDAASRAAGYSIDPVEPGGSGRRRMVILPAKLESDRGANYTVSHTSSNSIV
MTSWEADERARAEERGGVQRRGDWDQEGVGCFVSHPVNELHFKLSLPASLSEVRPYLRCD
RLSGFPNFKINEWGDAELPDNPVFDIDTEMEDGEGRSPYYDPADKMWHLVIHRPVVGYRY
RLRWQTPGLPPDQPIPGETLQWRELLLNMVDREVATDADNEAQRVFGLLADEFEKRLGWL
GTGEYRTVELFVYDSRLVVLRPVARRSSHPLHDDWRKFQVPLGDGIAGAAFQRRSIVPWA
EQDNEAIFIKPIPDPTLPVELRTILAVPIYHHGVQDDRQPSPSGAIGVISFGSSSPASKI
STLLNRSLTPQDEEKLKILRGLAQSHVHKMITALGQPDLP
>A0A603BCB8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae serovar 50:b:z6|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A8C1UL28|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyprinus carpio|TrEMBL
MCGVIPKQLNRCMCSYLNFNVFFFFSVCSFDVENGPSASCSPLDPQASPGSGLVLHANFP
SHNQRRESFLYRSDSDYDLSPKSMSRNSSIVSELHGDDMIVTPFAQVLASLRSVRNNFTV
LTNVQCASNKRSPVSNQPPITRVCLPGKSYNLTPV
>A0A1A8S658|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothobranchius rachovii|TrEMBL
RFTVAHTCFDVENGPSASCSPLDPQASPGSGLVLHTNFPGHNQRRESFLYRSDSDYELSP
KSMSRNSSIASELHGDDLIVTPFAQVLASLRSVRNNFTILTNVQCPSSKRSPAATTLPPI
TKVCLPDEAYQKLAMETMEELDWCL
>A0A8G1Y503|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. p99-361|TrEMBL
MHADHPRPVHVVQLTDAHLFADPAGSMLGLKTRESLGHVVAQVRREQPLVDLLLCTGDLS
QDASVASYEAFRELTAPFGVQSRWLPGNHDEARIMAEVAPELVQAVTDIGAWRIVMLNTA
VHGATHGLLGDDQLAVLEAALKGAGGRHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDII
EGYPQVRALLWGHVHQEWDEVRDGRRLLATPSTCIQFAARSEDFKVSEEQPGYRWLRLHA
DGRLETGVERAWDFEVKLDFDSPGY
>A0A519JD01|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp|TrEMBL
MTLYKNNADQQDWTIIQISDTHLMNQEDLEFVHMNPEHSFHSVIRQIQQQYPDTDAIIHT
GDLAQVPVEETYSRYLAFMQTLGIPFYQIPGNHDNIDIFPFYQHKNQAQAIHFGRWSLVL
LNSAVHDRIDGWIEQEQLQQLDILLAKLQQQFVIVACHHHPFEMQSKWIDQHKLKNTQNL
TDILAKHSNVKAVIFGHVHQDSCTEWQHIQFFSTPSTCVQFKPLSEDFALDDQAPGFRVL
HLRANGELETQIHRVHTARQQINSEISGY
>A0A670JSB8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Podarcis muralis|TrEMBL
LIQGFHFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSM
SRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLPDRAPSKRSPMCNQPSINKA
TITGKTT
>A0A4U6LS89|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. wls619|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQCVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLANYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>V5FGK6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio halioticoli NBRC 102217|TrEMBL
MEPHIVVTEETVQLLQITDTHLFADDEGCLLSVNTGLSFQAVVDDIAAHNLPFDAIIATG
DISQDHSVASYNRFANGIKKLVKPCYWLPGNHDLQANMGKVLPSEQINEVSHVFAGDYWQ
LIMLNSQVEGLPHGYLEQHELDLLDEKLSQHPERHTLVLLHHNSLPIGSTWLDQHKLQKA
DQFWRVLEKHNNVRAVLGGHVHQDFEQECHGIKVIATPSTCIQFKANTHEFALDTLPPGW
RHIQLHKDGRLDSQLHRLDEGCFVPDFDAQGY
>E0IVX3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli (strain ATCC 9637 / CCM 2024 / DSM 1116 / LMG 11080 / NBRC 13500 / NCIMB 8666 / NRRL B-766 / W)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A1Q9P979|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Heimdallarchaeota archaeon AB_125|TrEMBL
MQVKSKSLFFITILVLIASIFLSQYQVIEVIPKDDKRSSFELSSVNATSPIEYFNETSFP
RYTLVGKPLSLIQSPNKGFPVIIETDEILLIEAQAVSETTNWQFKLVSTANNISLDILAP
TFDISDNLWHFSTAPEEYIPGLYDLQLNCSAGDDYQTHTVKIVNQKTYPFKILHISDAHF
PSYDGKNTTDINLDYIEHINALDADFAIFTGDLIDGYSARDFVNPDTGDPLAAEVQIKLS
LWAFDMIELPIYYVGGNHDLDSSTSLPDNPSDVWTKYFGKNYMFFNYIDWSFIGYTCSSS
GLTKKGLNSVSSVFSTEKNKPNVLFYHADFMNQASNYRASYNIEVMLYGHEHHEEKYVSD
STLYHCEAPMFNNESSVITVLNETSVSLDDVVYDFSSLLEIPTTKTNFSIIFTLVTFQIV
LLSRIKRRRKAE
>A0A1B6D319|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clastoptera arizonana|TrEMBL
RTDVLVRDEDCDTQVNELAAESNCEPLCHRLQQIKTNSPKQHAFRVLLVFAKDDSACSTL
SGASEHLGFSREVASTLEQALELYQAHSSPPQIVFIDMRFSWFHGEKICRSLRAVKKSNH
VIFVAICKKNVVDKDEKELRSALKLGFNRVLVEPLSITQCVCELVQLAHGQLDLHSILAQ
NEAIYLALDKSRDLVLVTDSLHVIQYVNRTWCQVLGYKSEDLIGRSLHSFHQLGNMDPVT
RQLEKGFDWEGKISWRSKSGENITLQCRAMPYQAIGSEPTHYVYVQDNPLENHIYPRGSI
PSIRKGSYDLKSINSEGAQSARRQSLAKLHNLPLEAPITRVISLICAAQENSTGQVVQIL
DKVVDILRTTELYSSHLKADNLRCEDPVTSDLIGALITQGPVPVSTTRRSSNDSAAVKAQ
QAGLSGNKPIFSMSASPQLKELLDTSLQWDFNIFKLEEITGKRPLVYLGMNLLMHFDVHK
TLGCDEKTLYNWLTVIERNYHLSNTYHNSTHAADVLQAMAGFLEKERIKRLVDELDEACC
LIAAATHDIDHPGKSSAFLCNAGNELALLYNDVSVLESHHAALTFKLTLRDDRVNIFKGL
ERDTYKVARQSIIDMILATEMTKHFEHLAKFVSVFNKPSPTSEDGNCDNRFFDSSSSSDT
EIASMVPTFSQHRVDVTSGVFQNHMVYM
>A0A7J7S597|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pipistrellus kuhlii|TrEMBL
MGCAPSIHISETQTVYPGAREAEAAPQGPAVAAALLPPTPGRPGAQLPSPEPEAAAAAAA
VAAPPAEPRDSKASTSHVQFGPMRFRADPPQVLLVFVKDDSQCKGFRKACEKAGFPYTVV
QEVKVVLTCFLAAHHDIIIIDHRNPQQLDAPALCRSIRSSKVSENTVIVGVVRKRDGEES
VMPLISAGFTRRYVENPSLMACYAELLQLEFGEVRSQLKLRACNSVFTALEKSQDAIKIT
SENNYIQYVNPAFENTVGYEAGELIGKELARVSVNEKKGDLLTTINSCMKMRKEWQGIYC
SKNGDNVQQNVKIIPVIGQGGKIRHYVSIINGSSKDEKLIEPAQADIHTDSQSGKHRDKR
KSSLDVRSVTSRASEVATQRRHSSMARIHSMVMEAPITKVINIINAVQENSSARVTEALD
HVLEILRTTELYSPQFEAKDEDPHANDLIEGLISDGFRRLSGNEYTLSTNDPQQVPGGFF
PSGFLHHVPPPIAQAMENEEDWDFNVFDLEAATQKRPLIFLGLKIFARFGVSEFLKCSDT
TLQLWLQTIEAHYHSSNPYHNSTHAADVLQATAYFLRQERVKRTLDSVDKAAALIAAAVH
DVDHPGRTSPFLCNAGSELAVLYNDVAVLESHHAALTFQLTLRDDKINIFKNLERSDYRT
LRHAIIDMVLATEMTKHFEHVNKFVNGVVKPLAELEESEDSDPDPDALHLMLRTPETRTL
IKRMMIKCADVSNPCRPLEQYIEWAARISEEYFSQTEEEKKLNLPVVMPVFDRNTCSIPK
SQISFIDYFVTDMYDAWDDFVDLQELLQHLDRNFKYWKGLDERNLRGLRPPPELYQ
>S4RGZ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Petromyzon marinus|TrEMBL
HGDDLIVTPFAQVLASLRSVRNNFSALTNLQGTPSRRSPAGNQTSYPRAAPSDEGYQKLA
LETMEELDWCLDQLEAVQTHRSVSEMASNKFKRMLNRELSHLSEMSRSGNQVSEFISSTF
MDKQHEMEVPSAGHKEKERQRRPLASGGGVAAVGGAAPAVPSQLAAGVSHISGVQRLLHG
AAILQRAMIFRDALSQELEDINKWGINIFRIAELSNNRPLTVLMYTIFQERELLKTFQIP
ADTFVTYMMTLEDHHAGVAYHNSLHAADVAQSTHVLLASPALDAVFTDLEILAAIFASAI
HDVDHPGVSNQFLISTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLGKKQRQT
LRKMVIDMV
>A0A6M5Z8Z3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alcanivorax sp. IO_7|TrEMBL
MTQPVQPLRVVQLSDFHLFADPEGRLLGLNTQFSLEKVLERVREEQAAPDLVVATGDLSQ
DGSFESYQRLERTLADLPAPIYWLEGNHDKPAPMMHALKTHEQRISPCVAELGPWTLVLL
DSTIPGEVPGDLFEEDLAFLDRALDEARGEHLLVCLHHHPVPMNSRWLDTQLVGSAERFF
QVIDAHPRVRGILWGHVHQEYDAERNGVRLLAVPSTCVQFKPGSEDFAVDDANPGYRWLD
LYPDGRIDTAVSRVEGIDFKVDFSVKGY
>A0A2S9YUJ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enhygromyxa salina|TrEMBL
MIFWWPSKYHADYELRNWDALVQTVQTMPHGVFWPLLGARRSGKTWALNAIEAAIGPANA
AHVTLDQIDAKKQELPEHARGRTVLLFDEPGSVLFHDTAPEQVMNKGWELNVEGAKQFVE
WCQRLKHTGTIVTLALTPAEWHALREVGGALVSSKDLEYRRLGPLSAAQSQRFPRTPTQH
QLFEQLPPTWRRNPFLLAEFFRHVLDTPEGNLRNPLSRDDIHKFGKEVIGELNSGKYDYL
YHVLYDCLIPEHRGALRMVAEHERPSEDLCRMLLHLGLLMQSDSGEYEIGDPVLADHYPP
PVRIHHISDLHFGPKTALSVDAKDNSVQGRKLAKAAGQGPIRDDYLDWLAQLETHQRPHL
VVVSGDIAEAGQDDQLEAGRAWLDRVAACLAPHPGLDPDDPRLLLVPGNHDVDWTAVDGP
AGGRRPHLAFARVFTGTSWPFPQLVEPPETREPAHQHYRSLGLAFALLGSPEYGGANHEH
YGRLDPGLVHDRDIQHLRSAVWKHEPIRIAVVHHPLAQVPSIATEITSYSGLTNGGQLQA
ALEEQGFTLLLHGHTHAAYLERKGELLIAGAGTLGSRETYERHGFNEIIVTREGQRYKVQ
AQTYERKGGSFAPRAVEQLERVAT
>A0A2S9Y2N5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enhygromyxa salina|TrEMBL
MRSLVLPALVLTAALSQLGCIAVVIEASDDESGETSGDGDGDGDGDGDTGDGDGDGDPDT
GPGDGDGDTGDGDPDRFRVVVIADPHIPAPDYDGQDKSLEEARASLLETRDKIAAIVPPP
SFVVVLGDLVDDAYQTGDAVWYQANPNAFADVADIFAGFSVPVYPLFGDSDYAVPTYPKT
FSHQLFGQFYAKDPYYAVDHLGWRFVFTNSEYGQTFDEGTLIYDPTRGSYGGTQLNWIAD
QLGAGMPTVMFSHFPLFQVAVNEAPNNGQHTDMETVLTLQGESVKLLMAGHEQKWLDMPA
SYPAPLVVFGATRYDTDNFLLIEFMANRSQYEILDRDKVVWDQAEADTWIYDGTPSPE
>A0A375H885|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cupriavidus neocaledonicus|TrEMBL
MMQSAPQASPYLVAHITDLHIKAGGKLSYRRVDTAGALRQCIDTLLALPQRPDVAVVTGD
LVDFGSEDEYRFLRGMLEALPMPVRLMPGNHDSRGALRRVFADHADHAYLFAAGDADAPV
HYRIDAGPLTLIAFDCTVPGQSGGRVDPDALPWLEAALAAAPQRPTLLMLHHPPFHTGIG
HMDRQGLENAALLEIVVRRHPQVERVLCGHLHRHITRRFGGTIAMTAPGPAHQVALDLDP
QAASCFRMEPPGMLLHWWHPVHGLVTHAVAIGDHGPAYPFFDAQGKLID
>A0A3A3ZYR0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium polaris|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKARQDTFDLIV
ATGDLAQDHTLQAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPERFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSTVLERYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPDGRLETEVYRLSGNEFLPDMDSDGY
>A0A5Q4FIY8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chromatiaceae bacterium|TrEMBL
MSDMGAHVSPLRILQITDLHLCPQPGDVMGSGINTDDSLQRVLAQVKRQEPHLDRALVTG
DLVHDPVPEAYQRVSQQLNALPCPVHCLPGNHDDTDLMEDTLAGSHLHCGKILSQDDWLI
VLLNSAVPEESHGRLEDTELDLLEESLSRHPSRHALVCLHHPVVPVGTPWMDRIGLRNAD
DFWGVIDQHDKVRAVIFGHAHQVVDQTRNGVRLLCAPSTGAQFAPGSQTVRLDDLPPGYR
RLDLFPDGRIHTWVEYLPQAPEWRLCGS
>A0A5E7FIZ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MNRPFLVAQISDLHLKAGQRLTYGVVDTLGALRRAVDHLNASLPRPDIVVVSGDLVDFGR
ADEYAVLHPELARLQMPCYLVPGNHDTRGPLLEAFRDHPYLPASADGPLDWVVDDHPLRL
IGLDSTIPGGHGGQLLDSQLQWLDEQLALRPHAPTLLILHHPPFISGIGHMDREPFINAA
ALEQVVARHPQVERLLCGHLHRPMQRRFGGSVSCVCPGTSHQIVLDLQEAAPAHFNLEPA
GYLLHRWEAQQGLISHNGVFGDYPGPYPFYDAHGLID
>A0A5E6ZVT4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPWENALPSVSTLTSDDSALLVQLSDSHLFAEAEGTLLGMNTRDSLQKVIELVRTQQPQI
DLVIASGDLSQDGTLESYQWFRDMTRQIDAPARWIPGNHDEPQIMAEAATQSQLLESVVD
LGNWRVTLLDSAVPGSVPGYLQDGQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWLEPI
GLRNPEALFAVLDRFPQVRAVLWGHVHQEIDQLRNGVRLLASPSTCIQFEPGSEEFKVDD
LAPGYRWLRLLPDGRLETGVERVTGFDFQVDYGGKGY
>A0A7Y1F291|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas veronii|TrEMBL
MPRVPTVTPDAPAVLVQLSDSHLFAEADATLVGMNTRESLQRVIGLVREQQPRIDLLLAT
GDLSQDGTLASYQHFREMTAPFGVPARWIPGNHDEPQIMAHAALHSDLLEPVVDVGNWRI
TLLDSAVPGSVPGYLQDSQLQLLAQALSEAPHRHHLVCFHHHPVPVGCAWMEPIGLRNPE
ALFAVLDRFPQVRALLWGHVHQEIDRERNGVRLLASPSTCIQFTPGSEDFNVSTEAPGYR
WLRLHTDGRLETGVERVKGFAFTVDYASNGY
>A0A7Y1F960|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas veronii|TrEMBL
MPRVPTVTPDAPAVLVQLSDSHLFAEADATLVGMNTRESLQRVIGLVREQQPRIDLLLAT
GDLSQDGTLASYQHFREMTAPFGVPARWIPGNHDEPQIMAHAALHSDLLEPVVDIGNWRI
TLLDSAVPGSVPGYLQDSQLQLLAQALSEAPHRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVRALLWGHVHQEIDRERNGVRLLASPSTCIQFTPGSEDFNVSTEAPGYR
WLRLHADGRLETGVERVKGFAFTVDYASNGY
>A8TBY9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. AND4|TrEMBL
MQSSSGSIKLLQITDTHLFATGEGSLLSVRTADSFTAVVQEILRRQVQYEYILATGDISQ
DHSEASYQCFAEGIAPLQKDCFWLPGNHDYKPNMSSVLPSPQIQAAEHVMLGEHWQLVLL
DSQVVGVPHGRLSDQQLALLEEKLAENPQRHTLVLLHHHPLLVGSAWLDQHALKDADAFW
QVVDRFENVKGILCGHVHQDINLLYNGIRVMATPSTCVQFKPDSDDFALDTESPGWRELE
LHSNGDITTEVNRLPDGLFQPDFNSNGY
>A0A3V6R0I6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella berta|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A6S7D562|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter anxifer|TrEMBL
MTRILHFSDTHFGTERKPVVEAALDLARTLEPDLVVLSGDITQRARRSQFAAARKFIERL
SLPVLTVPGNHDIPLFNVFARALNPYGNYKRALGPVLEPVFENAGLLAIGVNTTRPKRRK
DGEISASQIARVAERLRQARPGQLRVVVAHHPVRAKVESDRHNLLIGRERALEAWAQAGV
DLVLGGHIHLPYVLPLDPAATAGGWIVQAGTTCSRRVRGNVPNSVNVITREGQGECHVER
WDYAVGAHAFAPVDKTLVALY
>A0A674JBG6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Terrapene carolina triunguis|TrEMBL
QGGQGHSPHGPGLPRGNGSLRAPSPMPPASLSAEDACQKLAVETLEELDWCLDQLETLQT
RHSVSEMASNKVRDAAAPRGSLRSLSDPDRKQRHCSCL
>A0A2G9RTL9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lithobates catesbeianus|TrEMBL
MGCSLWAKFKRMLNRELTHLSETSRSGNQVSEYISSTFLEKQHEVEIPSPTTKEKEKKKR
PMSQISGVKKLTHSSSLTICSIPRFGVKTDQEELLSKEIEEANKWGLDIFKVAEYSGNRP
LTVIMYGIFQERDLLKTFRIPSDTFITYMMTLEDHYHSDVAYHNNIHAADVAQSTHVLLS
TPALEVSVFSAFCEYSIFIIKVNRASLNGDPRSRSGPNRSHPDRSGRAIKKPVLLSAVTL
QSS
>G5Q1Q7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Montevideo str. S5-403|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A375A663|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dickeya aquatica|TrEMBL
MESLLTLPVARGARIRILQITDTHLFADERGTLLGVDTYRSYHAVLDAIAAQQDAFDLIT
ATGDLAQDHTQEAYTHFADGIRRFNAPCVWLPGNHDFQPAMVDVLARCGIAPSKHVLLGE
QWQVILLDSQVFGVPHGALSDYQLEWLERSLQGQPERHTLLMLHHHPLPSGCTWLDQHSL
RNAHSLDALLAHYPRVKTVVCGHIHQELDEDWNGRRLLATPSTCVQFKPHCTNFTIDNVA
PGWRYLDLLADGTVETRIGRLEGCEFLPDMDSDGY
>A0A7V7JDB8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQEAGISPAKCVFAGE
HWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPARHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLAKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLAGAQFRPDTASEGY
>A0A0M3F4T1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRVLQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEKREYDLIV
ATGDLAQDQTAAAYQRFAEGIASFSVPCVWLPGNHDFQPAMYSALQDAGISPAKRVFVGE
HWQILLLDSQVFGVPHGELSEFQLEWLEDKLNAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDQVLVKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLQGTAFRPDTASEGY
>A0A6F9ZBA5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacteroidaceae bacterium|TrEMBL
MKSLEIIKAFATVGKKPFFLAGDMNAEPESEFIKGLQKDFQILSNTKQHTFPAPNPEKTI
DYIVALKQNAEGLAVTSSKVLNEPVASDHRPLIVDLRTAEKAEKIFRTKPYLQNPVDNGM
TVMWETTVPAYCWVEYGTDSTQLKRARTIVDGQVICNNMLHKIRINNLQPGQKYFYRVCS
QEILLYQAYKKVFGNTAQSPFSEFTVPAANDDSFTAIVFNDLHQHTNTFRALCKQIENVD
YDFVVFNGDCVDDPVSHDQATGFISELTEGVHGDRIPTFFMRGNHEIRNAYSIGLRDHYD
YVGNKTYGSFNWGDTRIVMLDCGEDKVDDHWVYYGLNDFTQLRNEQVDFLKKELASKAFK
KAGKRILIHHIPLYGNDGKNLCEDLWKKILEKAPFNISLNAHTHKYAYHPEKELDNHYPV
IIGGGYKMDGATVIIIEKKKDELRIKVLNAKGETLLNITV
>A0A737IXG8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae serovar 42:b:1,5|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A6M1YRF7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Anoxychlamydiales bacterium|TrEMBL
MLTIAHLSDLHFSKISILPLSLKRFVGTANLLITRKRSYIDTHLFKLPKLLKSLDVKNIL
ITGDLSSTSLKKEFEKAKEFIDSFDENIKFFLIPGNHDTYTKKALKNSYFKNILKSQNIL
DTKHKKIHFHNLSKNWVYIGLDTTLVTPIFSASGLFSKEMQIDLTAILDKIPKDKNIIIS
NHFPIFYKAPKRKLLKRSNALLEILKSYPNIKLYLHGHTHKSSIINKENLPIMICSGCSS
HKKNASFNILQIEDDKCVIQSHVLKDNTWQKDKENQFNFS
>A0A8B3IF11|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas xanthomarina|TrEMBL
MPGASLTVEDSVLLVQLTDSHLFAEADGKLLGMNTCDSLEQVVELAIDEQPRIDLILATG
DLSQDGSVASYQRFRRLTERIEAPARWCPGNHDELAAMREACRGSALMEPVLEIGGWRVV
MLDTLVAGSVFGVLRNDQLELLERALSEAPDHHHLICLHHHPVSIGSRWMDTIGLRNPEA
LFEVLDRHSNVRALLWGHIHQEFDSWRNDVRLLASPSTGVQFAPQSEDFQVDNVAPGYRW
LRLYADGQLETGVSRVSGIEFEIDYSVKGY
>A0A5P9CLH4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio aquimaris|TrEMBL
MKVTSSSVDGSIRLLQITDTHLFEANDGSLLGVNTSDSFDAVVSAITEQNTNYEAIVATG
DISQDHSALSYQRFESGISKLNKTCFWLPGNHDFRPNMDSVLCSQQIQYLEHLLLGDYWQ
MIVLDSQVVGVPHGRLSEEQLSLIEDKLNLYPERYALILLHHHPVLIGSAWLDQHTLKDS
ESFWKVIEKHSNAKAVLCGHVHQDMDRYRHDVRVMATPSTCVQFKPLSDDFAVDNQSPGW
REIVLHPSGNLTTEVKRLPMGSFIPDFSSSGY
>D3GVU1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O44:H18 (strain 042 / EAEC)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A645BPB3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MPDVRYGRLHSQSATALALAAQELARSGAEFILLPGDVTDASRSEELKAAAKALQTVKLP
DYAVPGNHDRLQDPKLAALWQQYFGAPARLEKHAGVQLLALDTGDGKLNQPANRAAIEAL
DPALPVIVFTHYQLAPDDQIKDDDKAISDAAESAVLLDKLKAMNGFVFVGHKNVATTARL
GRMTQLNAPQLTQFPAGYLVADLYDDGLLLRFVPALDEFFDEYGRLRSGRYKQTAKLRDR
RSLELWNAFYPADFSAARP
>A0A644VSU0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKKSYFLPLGVALILGFVSCNEANEEPVVVNPFDTISVSSNDARDKIVVISDLHLGNDLS
YSENVKHLQRLEEFLNEVRSSATIRELVLGGDIFDDWYVPTRIDAYGDGSQADFIRKTVA
ANQGVFNVLNGIIKDGKIRLTYIPGNHDMGFTAESVDVALPGVNQARDSEVKYGIGTYNP
EGYPQIAIEHGHRYDFFCAMTPNANEEDAPGATLPPGYFFARIAANSFTDPTTMQEATKV
PLVMLNDQANAEQRSKYIYYNLWKTVMEEVIYVKDDFSEPIIKTNVGNYTKTYSINDILP
KNSAVDGSIQINLYNGIFTQDNWNERLKYNNVDVLTVIDTAIVGSLHTTFIDEQSNVQYF
SNSNSSARLVVFGHTHEPMIKSYVNLDKEPCLYVNSGTWEDQKTRDKNAPIDQDRLKMHF
VIISPIQSDKKKLQVSLNQYRYGKHVLMEREELRL
>A0A644VSP1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MIRSCKKVLLMTMVFFLIFPLGSVFANDANGWYHIPVLTDCHYPVKTKTTLSASAQERLI
ANKLKAIETLNHWSDIDFIAFLGDIIPDGGNETEWNHAKDFFSRLKKPIVAIAGNHEYSY
VDNRDAKGKLALASKEQKESKYSKFKDLFNISGDVFQSRIVGRYLLVFLNPDIDTKNLVE
LNERQLQWFENELSTHPDMPTIVFCHAPLLGTQFNWEENDTNLPKKAVQPAKAISSILNN
HKQVFMWVSGHTHTPPTVSSFNHPVNIYQGRVVNIHCPAWEEEPLWLNSLYLFPDKVMIR
TFNFNTGNWEEKLDRVVFPNDVPVYHDVAFTDPLRPAM
>A0A644Z2W2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKKYSFFLLLLFLFPSTNVVSQPVRIAILSDIHYLSPEIAQPGAALEKYETATGRNISDL
HAVLDKTLAEIEAAGTDILLITGDITNHGEKQSHIDFTKKLYPLQQRGMRILVIPGNHDI
NIPDSRAYIGEIPAPTQSISAKEFPEIYGPFGYNGALKLDTASLSYLAEINENTWLLCFD
TNRYAEHKTTSVSGGRILPSTMNWALDILRQAKAKNVTVLGMMHHGIVEHMPYQATFFPG
HILENWESAAGILAAAGLKIVFTGHFHSNDITQFTGSAENILYDVETGSLSQYPFPYRLI
TLDSTSLSIDTRFIESVPGTAGLQDKYRKTTESIIRRGVRARLQQTGIPFADDAREALVE
LLTGLNVLHLKGDEVLDEGMLRSIQQFAEVMGDENFDINSFQLDFPPADNKLKINLK
>A0A7G2CY89|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microbacterium sp. Nx66|TrEMBL
MILTEHPRPSHTFVHISDTHLPGERSPLYGSGADADANLAEMLDRLVASGLRPDALLFTG
DLTDRGDAAAYRRLRELVAPAAAALGCEVVWAAGNHDDRRAMRSELGLAGAGDEPIVEVR
WFGGMRVIVVDSTVPGAHWGEVPSSQLVRLEGELSTAAPQGTLLLIHHPPLPTVLDLAVT
VELRDQDALAAVLRGSDVRGILSGHVHHPSFGTFAGIPVAVASSSAYGQDLAQPVGATRG
QDAAQGYNLVHVYADTIVHSAVSLERGADVGEPVAADEAGRRIAGVGIDWRD
>A0A3B0MX78|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Roseibaca ekhonensis|TrEMBL
MIRFLHASDLHLGKPFGGFAEEVRQRLRQARQESIGALAKAARDGGASHVLLAGDTFDAE
TPARATLRQAMNTMAGHDDLTWVLMPGNHDHLGASEIWGTLERERPDNVTLALASEPLAL
AGGAVLLPAPCTTRNPGRDLTEWMDGADTGEAIRIGLGHGSIRDFRSVDEMGGEGGAVIA
PDRARRAGLDYLGFGDWHGRIEVTPNTWYSGTPEPDSFKPHRPAGALLVGLASRGAAPEV
TEVMTGQIGWTRVTLDLLDTEDPTERLTEALPELARRERTLIDIRATGRTGLAGHAALAR
AIEEFAPDFLWANGDLSALAVTHEADDLSLIDDRGAVRDAAEALAAAADAGDTAAAAALT
RLFSYALEVK
>A0A849R2J5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methyloglobulus sp|TrEMBL
MHETSNHLSILQITDPHILSTSEATLLGVNTAYYFNAVIEYAFSSGRHFDICLITGDLAQ
DPCTASYEHILDRLQPHNIPCLCLPGNHDDFEIMQTVLCTERVNCRKKIALGNWQIINLN
SQIPRSADGYLSVEELAFLERSLRDSPDFYTLIAVHHHCLPSGSHWMDTMMIKNAEDLFD
LIKRHPNVKAIINGHIHQATDIQIDGLRILSTPSTCFQFKPQSEHFSLDDKSPGYRWINL
SVDGSISTDIVRIPERLTGLQIDTEGY
>A0A6S7EL85|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter pulmonis|TrEMBL
MLIAQITDLHMRTPGDKAYGIIDPAAFLGPAVRALNALTPRPDCVLITGDLTDLGRPHEY
QALRAQLQALEIPYFLLPGNHDDRAQLRAAFPEHGYLQGQGPFIQYAVETWPLRLLALDT
VVPMKSHGELCDARLGWLAARLAEQPGRPTLVLMHHPPFLTGIEHMDDIGLLAGAPELER
IVARYPNVERVLCGHLHRTIFRRFGGTIASTCPGTAHQLALELGPRPTLQYIMEPPGYQL
HWWHDGALVTHHAVIGEYPGPYPFA
>A0A192CBN1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O25b:H4|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A1X1PN34|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Burkholderia puraquae|TrEMBL
MSSSTPTNPSRRKALQCMAFGGLGTLFTLSGGILTPFDLALAQAGDALTATAGRPLFVQI
SDTHIGFNKDANPDVSATLKQTIELVNGMPATPALAIHTGDITHLSKPEEFDHASQLLSA
LRVPELHTVPGEHDVTDGSGAEYFSRFGKASDNRGYYSFDHAGVHFIGLVNVMHFKPNGL
GSFGDDQLAWLAQDLKGRSSSTPIVVFSHMPMWTIYEPWGWGTGDAPQTMALLRRFGSVT
VLNGHIHQIVSKVEGNVTFHTARSTAFPQPTAGNGPGPVPLTVPRDRLPSMLGVTTVEFA
GHPVASSLHDATLA
>B1G957|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia graminis (strain ATCC 700544 / DSM 17151 / LMG 18924 / NCIMB 13744 / C4D1M)|TrEMBL
MLLAQISDLHIKRPGALAYRRVDTAAHFARCVDALNALDPRPDVVIMTGDLVDQGEPQQY
EHLKTLLAPLQIPYFLLVGNHDDRAALRAAFPDRAELHGGDEFVQYAADIGPLRLIALDS
MVPGQSAGTLCDARLSWLAAQLDAANGKPTVVALHHPPFACGIGHMDALRLDPLAADKLA
ALIARYPNVERVICGHVHRPMFVRFGGTIASAVPAPAHQVALDLRDDAPSAFMMEPPAYA
LHRYDPATGIVTHHAYVDAADGPYPFYEPEGALID
>A0A7M7M5Y3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Apis mellifera|TrEMBL
MIMHSSRYMYAKHSSCLDGKTEYDILGRKLSFEDVGDEKNADYSTLIGSHDTEPHPLTNS
IPSLIKILLVFPKDDQQMDILATTSRRLGWSVSVAKDAEKALEFFQARGHELVIIDHRGQ
RAAEADIICRAIRASPFYYNSIIIALVKKSYLMHSESEKIVTLDLMEIGYTKTLMECAHE
RILINELVGIYTSGILPRTQLVAVNMLYMALDRCRDMIHVTDDKYIIQFANKISEKLLGY
RINELWGKNITDLILYDNFIQMEQHIVKGREYDGNINCIRRNNQMLTINCRVIPFAYFKK
PTHYIFIYDTTYLSETIQPLLQPITHPKTVVIAQKRVSEINFKGIQEVRRRLSKRDLQTL
QLEAPITKVIALLTASIKEDTSSETRLQIEQAIDILKTTELYSPVFKEPGDPATDFIEAL
ITPKKSWDIRKPSIESVRETPAKTLAASTRMQIKGYRGPQEIAEILEKSLEWDFDIFKLE
ILTEKRALLFLGMTIMNLFRVPARLGCEEKIVQNWLIVIEANYDITNRYHNSTHAADVLQ
AAAMFMQTERLKQVLEPLDEVATLIAAAAHDIDHPGRSSQFLCNSDNKLAILYNDLTVLE
SHHAALTFKLTLSDDNVNIFKNLERDTYKQVRQSVIDMILATEMTKHFEHLAKFMNAFST
RIPEMYIEGSQDLDLSAAILPENVILVKRMIIKCADVSNPTRPLKYCVEWARRIAEEYFS
QTDEEKQLHLPVMMPMFDRITCSIPRAQIGFIDFIINDMVEAWDVFINMPEIVGFMRQNY
DKWKEYNEKGITTLQDIEKIQEAIPELKLDSMNT
>A0A5J2KAY0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Napoli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGILETEVHRLQDTRFRPDTASEGY
>A0A0C6FJD1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas aeruginosa|TrEMBL
MSRHSNTPATDASVLLVQLSDSHLFAEDGARLLGMDTAHSLEKVVERVAREQPRIDLILA
TGDVSQDGSLDSYTRFRRLSAPLAAPLRWFAGNHDEREPMQRATEGSDLLEQVVDVGNWR
VVLLDSSIPGAVPGYLEDDQLDLLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGY
RWLRLHDDGRLETGISRVDDVVFEVDYDTAGY
>A0A3V9E3I9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Havana|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A345M1H1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia huaxiensis|TrEMBL
MDSQLEVTAKNSKIVRILQVTDTHLFANTENTLLGVNTYKSYQAVLDAITEENLPIDLIV
ATGDLVQDQSPQAYQHFADGIARIPAPCVWLPGNHDYPPAMVETLRVAGISSAKQILIGD
EWQILMLDSQLQDVPHGELSEQQLEWMKASLDAEPERTTLIMLHHHPLASGCTWLDQHSL
RNSHILADYLKNYSNVKAMLCGHIHQEMDENWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELSINEQNQRHITTRVHRLDTREFSPDLDSDGY
>A0A0T7RRH8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Bovismorbificans|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRKLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A661CC58|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MNDHFKIEPSNQDYAELLQITDTHIFADEKDTFDDVDTRASLKQVLDLARGNDWPVDTIL
ATGDLVHDARTIAYERLLEVFTSIEEPVFCLPGNHDSPGLMYELLNTSNVHTSKSIEIGA
WVIIMLDSFLLNTHAGQLQQHELDLLGELLEKHQDKHVLVCLHHPPVEIGSDWMDGMRLN
NPQEFFAVLDRYNHVKAVLWGHIHQEFNAERKGVRLMASPSTCVQFMPESGEYRKDGRAA
GYRYLKLHSSGEIDTHTRRLHGVTG
>A0A0F5EVU3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Avibacterium paragallinarum|TrEMBL
MVNTYTYPTEKDVVRLVQITDPHLFKDENGELLGINTQASFNQVLREITQSPFDYELVLA
TGDLVQDSSNEGYQRFCESVQCLEKTVFWIPGNHDFQPKMFDILNQNNGNINPLKHLLIG
KHWQILMLDSQVSGVPHGQLGQYQIDWLLSKLRDYPERYSLVVLHHHILSTNSAWLDQHN
LRNALDLAYTLSPFSNVKGILYGHIHQAVDSEWRGYKVMATPSTCIQFKPDSNTFALDTL
QPGWREIELYSDGRIESRVKRIQHAQFSPNMLSEGY
>A0A6M4Z777|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas media|TrEMBL
METELPQAPDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQANAHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGDHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHQGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRIASQVWRLPVGQFVPDPDATGY
>A0A3V4QY31|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica I|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLVLQANGVLETEVHRLQDTRFRPDTASEGY
>A0A6M1YD94|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Anoxychlamydiales bacterium|TrEMBL
MNIFAIADLHLCFSTPNKSMEIFGPIWKDYEQKIKENWGKNISKDDLVLIAGDITWAMKL
KEALIDLEWIHNLPGKKIIIKGNHDYWWPSFSKLKTYLPPSIDFIQYNAITIGDISISGT
RLWDTDEFNFNDYINYIYNPKVKKNKNLEEEAQKELSQKIFVREIERLKLSLNQIDKNAK
TKIIMTHYPPISADLKDSKVSKLLDEYNIDISVFGHLHNVKTDIKKPFGQKNKTQYVLTS
SDFLNFNPIKIL
>A0A7D5IDD8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. LPB0260|TrEMBL
MPSVPTSAVESSVLLVQLSDSHLFAEAGGKLLGMDTQDSLQRVIELVLQEQPRIDLMLAS
GDLSQDGSEASYAHFRQLTAAIPAPARWFPGNHDELPAMHSACAGSDLLEPVVDLGNWRI
ILLDSSIPGAVPGYLADQQLELLERALSEAPERHHLICLHHHPVSIGCAWMEPIGVRNPE
ALFAVLERHSQARALLWGHIHQEFDQQRGDLRLLASPSTCVQFTPRSEDFQVDSCAPGYR
WLRLHDDGRLETGVSRVTGIQFEVDYSVKGY
>A0A315GVD4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar 4,[5],12:i:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5T3DCS1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFGAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A605YJY6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Paratyphi B|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A1Y3S122|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ligilactobacillus salivarius|TrEMBL
MKIAISSDNHLDVNRQDPDEIVSLQANYLNEQNVEYYLFAGDMFNDFQKTKSYFEKLNTL
ITGKAYFIAGNHDMLKNITFAGLENNNISDFYLHNAYIDIPNTDWRIIGNNGWYDYSFSP
TLTEDEIKRWKNTYWIDAGINQPISDNEREQLVLQQSRQQFELAKQAKKKVIFVTHFVPN
SKALWSKPATLKSDKEIRIFKMVNALLGSQHLGKLIQDYPEIKYVFYGHVHGWHEPFQIA
GATYLNQAVGVRKKKRKYHEWQKDTFMDQWKYRMNIINI
>A0A286X9I1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cavia porcellus|TrEMBL
GLCPWSPQGSGSRPGSPLLPPLGSCPWAPVEAELSPQVKFTMRARGTGQNRVLGSAGRME
EMDGGIFDLDNGPSCSRAAQAPGSHSQWAEPFLYPSDSDCELSPKAESRNSSAASDLYIK
AVCKPTRGFDWVRGPGLSPTAVSQQRRRPDHDTLCPGECHPVLPEPRAEPPLPPNSASRR
SWPVLVPAPPFPQFKRVLNRELIHLSETSGSRNQVSKYISRTFLDPAEPSPTQTSTLTWS
APAAPVRDCRPPRASKPGLSAATVLRFGEGQLAKELEDTNKWGLNVFQVVDLSGNRPLTA
ILFSIFQERDLLKTFQILVDMLATYLLTLEGHYLADVACHNSLHAADLAQSVHVLLLKPG
QEVFTDLEVLAAIFASAIHDVRRPPWRLQPLPLPAESELALMYGDISVLENHHLAVGFTL
LQADNCDIFWNLNAKQWLSLRRMVIDMVLATDMSKRMNLLADLKTMVETKKVTSLVLQNL
GHCTDLGNPTKPLPLYRQWTGPIMAEFFWQGDREHESSLAVSPMCHMHTASVEKSQVCGD
CTTWADLVHPDTLDLLDTLEDNRSWYRSRVPWSPLDMGGSEKGLMLEEAEEEQ
>A0A3D8GZ59|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter flavimaris|TrEMBL
MTTKEKNRPLRVLQLTDPHLMARADGDLLGVRTRESLQAVIAEVLKVHGQPDLILATGDL
AQDGSVEAYRVFGESLKSFSCPSVWIAGNHDHIDNLLQVSREYNASDRHVIQGGWQFVML
DSSVPGKVFGALAESELAFLSETLEQHPDIPAVIALHHHPVDIGSDWMEKIGLTNRDAFW
QVLDRFPQVRIVLWGHIHQEHERERNGMQLLATPSTCIQFTSGSSKFSVEDLPPGYRWFE
FHDYGDFATEVRRAEDFQFELDQNSSGY
>A0A6G8S8H2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter lanii|TrEMBL
MPLNPNEKIIIQITDSHLMDRADAQFVKMNPEQSFHAVIEDMLSQYPHIDAIIHTGDVAQ
VAKPETYARYQQYMQRLGIPFYQIPGNHDDVAHFPFAAPDPIPAVLSFHNWRFILLNSAV
PDRIDGWIGSEQLVHLERLLEQHQTHDVVLACHHHPLEMQSHWIDQHKLKNTKQLTEILQ
QYNNIKAVICGHVHQDSLNLWNNIQFLSTPATSVQFKPKSQDFALDDLAPGYRSFRLKEN
GEFETQVHRLTDFTQHINKDISGY
>A0A7G7RTK0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. B11D7D|TrEMBL
MVLPSLPTPPADSSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIERVQQEQPQIDLVL
ATGDLSQDGSIASYQRFRQLTSALAAPARWLAGNHDETPPMQAACKDSELLEPVIDLGAW
RIILLDSSIPGAVPGFLAASQLELLERALSEAPQHHHLICLHHHPVSIGCKWMEPIGLRN
ADVLFAILDRHPQARAVLWGHIHQEFDQLRGNLRLLASPSTCVQFAPGSEDFQVDDEAPG
YRWLRLHADGRLDTGVSRVTGIHFEVDYSVKGY
>A0A064DJ33|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter freundii MGH 56|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRAKYLLCGHIHQELDLNWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A9L1S8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella baltica (strain OS195)|TrEMBL
MLKEAVSYSIAEGESVRIVQVTDPHLFADPEAQLLGVNTGKSFDAVLNTIRAVDYPAHLM
LATGDLSQDYSAESYQQFVKAVTPVGLPCHYLPGNHDDPRIMYLHMQGEQIFGQQRILAG
NWQILMLDSTVRGKPGGNMAETQFELIDEAIAAHPECHTLLVMHHNPIVVNCTWLDQHCM
DNGAEFIARVAKYPQVKGLLWGHVHQCIDTHHNGPHGSMQLMATPSTCIQFKPLSPYFAL
DSVQPGYRLLELKADGSINTKVYRVPGNHFSPDNNSSGY
>A0A7Y1DVN9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas proteolytica|TrEMBL
MPSVSTVNPDAPALLVQLSDSHLFAEADGTLLGMNTRDSLQRVIELVRARQPQIDLLLAT
GDLSQDGTLESYQLFRDLSQQIGAPARWIPGNHDEPQVMAQATMGSALLESVVDVGNWRI
TLLDSAVPGSVPGYLAEPQLQLLAQALSEAPGRHHLVCFHHHPVPIGSAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRQRNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHPDGLLETGVERVEGFTFTVDYGSNGY
>A0A2S6TWH4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alphaproteobacteria bacterium MarineAlpha4_Bin2|TrEMBL
MILVQITDTHIEAPGELAYGRFDTARNLRAAIDVINQMDPAPDIVLHTGDMAHHGTSERY
SHFRELIADLRAPFFALPGNHDDRDNFRAAFSNTTWMPRGGEFLHYTIDDFPVRILCCDS
VLEGRVQGGFCSERLAWIEDQLSQASNQPTIVALHHPPFGSGMTGSTSNGLINGGSLFAA
VLKRHKQVVRVIAGHAHRPFTCAFGNTIGYAAPTTCYPFALEMGPQKILSIIDEPPAISV
HVWMEDTGVGEPGLVTHTLPIGEWGEPLVLLRNGERELTTA
>A0A7Z1WJB8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter baumannii|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIQQILKQHPEADAIIHT
GDLAQAPTPITYKRYINFMQTLGLPFFQTLGNHDNVDHFPLHNENHQQPVVVGLGNWRVI
MLNSAVKGKVDGHLSSEQLENLANLLEQFEDHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFQNVKALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLNNDGSFETKVFRLENFKTRINTDISGY
>A0A331EGN7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pneumoniae|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVFLGD
HWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A3Q8GAT4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurellaceae bacterium 12591|TrEMBL
MFSTYRYDTSAEVFKIIQITDPHLFKDEHGELLGINTFQSFSQVLHEIKASRFDYDLVLA
TGDLVQDSSREGYLHFCEQVKSLEKTVFWIPGNHDFQPKMFEILNQDQGNLNPKKHILLG
KSWQILMLDSQVFGVPHGELSQYQIDWLVAKLKDHPERYTLIVLHHHILPTHSTWLDQHN
LRNAHELAYALAPFDKVKGILHGHIHQEMDANWQGYRVMATPATCIQFKPDHNTFTLDSV
QPGWRELELHSDGRIETRVKRIQDKTFFPNMHEDGY
>A0A385XWT3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dickeya dianthicola|TrEMBL
MLLAQISDTHFRSSGQKLYGFIDINAGNADVVSQLNALTERPDAVVISGDIVNCGRPSEY
QVARQILGNLTYPLYIIPGNHDDKTHLLEYLQPLCPQLGNDPQNMRYAIDDFATRLLFID
SSRAGTSKGWLTQETLAWLEAQLMRDDKPTAVFMHHPPLALGSAQMDRIACENGHLLLAL
VERFPSLVRIFCGHNHCLIMTQYRQAVIATVPGTVHQVPYYHDDTRPYYDMSPPACLMHR
LVDQLWVSYLHPLSHYAGPWLYNESISCPVDER
>A0A7Y4EBH8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. RE88|TrEMBL
MKVTSCSSDGSIRLLQITDTHLFEATDGSLLSVNTADSFNAVVDAIVEESPAYDAVLATG
DISQDHSEVSYQRFEQGIVPLKKKCFWLPGNHDFKPSMNSVIPSQQIQQIDHVLLGDTWQ
MIMLDSQVVGVPHGRLSDKQLNLLEEKLSQYPERYTLILLHHHPLLVGSAWLDQHTLKDS
EDFWQVVDQHNNVKAVLCGHVHQDMNVMRNDVRVMATPSTCVQFKPNSDDFALDYQSPGW
RELLLRDNGEVEAQVKRLPAGSFQPDFNSAGY
>K8B0K5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cronobacter dublinensis 582|TrEMBL
MESLLNLPVAGGASVRILQITDTHLFAGKNDTLLGINTWESYQAVLAALHAGQREYDLIV
ATGDLAQDHTPEAYAHFAAGVSTLPAPCVWLPGNHDFQPAMFSTLQDAGISPAKRVFAGD
HWQVLLLDSQVFGVPHGELSDYQLEWLERMLQQAPERHTLLLLHHHPLPSGCGWLDQHSL
RNAQSLDDVLNRYPRVKHLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCAGFTLDTVA
PGWRWLNLHPDGSLTTEVCRLEGAQFRPDTASEGY
>K1ISL0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas veronii AMC34|TrEMBL
MRLLQITDTHLFASEEGRLLAVRTAESLAAVLEQVQANDHPYEVILATGDLSQDHSPESY
LRFASMMAPLGRPIYWLPGNHDDSPLMTEYLHAAGISESKQLVGNHWQVILLDTQVRGKP
HGMIGDHQLEALDRALRQYPDRHALIALHHQAVPVGCAWLDQHNLKNADDLFAVLARHPQ
QKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLCDGFALDESGPGWRYLTLYPDGRIA
SQVWRLPVGQFVPDPNATGY
>A0A5J4QSM1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MFAIVLGLHFYVFYRLWCMMPVSTIMWRTLFIVSAVIVVSSFFLSALIGNNLPSSVTSIM
YRVGTSWFFIFVYLLILFLLLDLLRLTHLFPIHRFMYGSWIGFGVLAGFLTVVMSLGYFK
YINKEKVELSLEINKDVAVSSLKIVAISDLHLGYGIHKKEFEQWVQLINKENPDIVLIAG
DVIDNHPRPLYEQNMAQAFKQLKTKYGVYAVLGNHEYISGVSKSIDFLKEAGIIVLRDSI
AFIDDTFYLIGRDDRTNKARKSIEELTDTLDKSKPFIMLDHQPYHLEEVEKNNIDLQISG
HTHHGQILPISWITNRMYEKSHGYLKKGNSHIYVSSGIGIWGGKFRIGTQSEYIVINLNI
KQNH
>A0A5J4S6V4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MKKLVSRKKFFVIGVLAGLLCYCAVFAQKPELKFHEDGTFKILQLSDLHVQHLNGKSEKA
INNINVLLEYEKPDFVIITGDLITLAPGEAGLQRIFEPIIRRRIPFAVTWGNHDNLDCGW
GDKAPNNNCDMSRHEMQDYVERQSYNVGFRVDGLNGESVFNIPIQSSTGNKDAFVLWVMD
SGSQSTLAEVKGSGWITSEQIEWYNRESKAFTNANGGTPVPALAFYHIPVPEYADAIRSV
TAQWTGYKLEGISCSAMNTGFFAATRINGDVMGHFCGHDHDNDFVIMWQGIMLGYCRFSG
GNTTYTHLDYTGGRVFILQEGVRKFETYVRLRNGDCIQRVSYPQLLKKIED
>A0A5J4QPG0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MRLTFILFMFAIVLGLHFYVFYRLWGMMPISTLMGRTLFVVSAVIAVSSFFLSVLIGNNL
PSSVTSIMYRVGTSWFFIFIYLLILFLLFDLLRLAHLLPVHRFMYESWIGFGVLAGFLAV
VLSLGYFNYIHKEKVELSLVIDKDVAMSSLKIAAISDLHLGYGIHRKEFEQWVQLINKEN
PDIVLIAGDVIDNHLRPLYEQNMAQAFKQLKTKYGVYAVLGNHEYISGASKSIDFLKEAG
IIVLRDSVAFIDDSFYIIGRDDRTNKARKSIEELTDTLDKSKLFVMLDHQPYHLEEVEKN
NIDLQLSGHTHHGQILPLSWITDRMYEKSHGYLKKGNSHIYVSSGIGIWGGKFRIGTQSE
YVVINLNMK
>A0A5J4SFY5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MKKSILIILCLFVTFLCTATQKPARPELKFRADGTFKIMQITDTHYRTNWAGREGALDLM
KQAIPLVNPDLVILTGDIVSSNKDTYELWTELTQVLVDAKVPWALVFGNHDDEFEITKPQ
IIEMITNLPYCLVENGPKEVAGNGNYVLKIASSTPPSKTKATIYCFDFPDERNGIMVSQL
EWYRQKSTAFTAANGNKPLPSLAFFHIPIPEYREVIDIPTTVGQCNEEICNFKINSGVLA
NFIACKDVMGTFVGHDHSNNYIGCLHDVCLAYGYCSGKQVANPIAGRGVRIIELFEGERK
FNTWLLKLYDSSFVENRWKPVSQVESFFFVTYPDSFKK
>A0A5J4QWU8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
VLITLLLGWALSVSAHDIAPNVDASTIFSTKPYLQNPIGNGITISWFTQVPTHGWIEYGT
DKNLTQKKELIVDGQVICNIKHHKIRLTNLQPGVTYYYRVCSREITLYQAYKKEFGDTAY
SGIYSFTLPSPNLSDFTAIIFNDLHKNKEVLDELSKQIKDIHYDLVFFNGDCIDDPNNET
EAVNFLSLMNEKIHAEAIPFFFLRGNHDIRNAYSLHLRNLFDYVGDKTYGAFSWGDTRFV
MLDSGEDKPDTTYVYYNLNDFDGLRHEQADFLHKELSGKEFKKANKKVLIHHIPMYGLAE
SYNPCLEFWGELLSKAPFDVCFNGHTHKHSFHPKGSLGNNYPVFIGGGNRVGTATVTILQ
KTGKVLTVKVLDAKGKILYQL
>A0A2H5WNW1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR14|TrEMBL
MLGLLGVLTAITGTGLGVGRWTRIRVETLPLPVQTPVRIAVLTDTHLVDDLSVRHLQSVL
QQVYAHQPDLIVIVGDVVSSRKDLPYIRKGFKGIRAPLGVYAVLGNHDHWSGGEAVRREL
EALGITVLMNESRTLRKGEAEFILAGIDDLYTGNPNWERTFRAIPPNPKQAVILLSHNPD
AALSPYRNRAHLILSGHTHAGQIWVPPGFHRLAKRLLGRSFLPQTEYGITHPYGLKREGK
TWVYVSSGVTLGRSVPRWFTRPEAVIIECTPP
>E3DEX3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia sp. (strain Ejp617)|TrEMBL
MDSLLKLPVASGSRVRILQITDTHLFAGKDETLLGVNTWASFDAVLEAVAAERRHFDLIV
ATGDLAQDHAVEAYQHFAEGIARLPAPCVWLPGNHDYQPTMFSTLGASSIADQKQVLIGD
HWQAVLLDSQVFGVPHGELSDYQLEWLERAMAAEPQRHTLILLHHHPLPSGCSWLDQHSL
RNPHMLDAVLRRYPLAKTLLCGHIHQELDLNWHGRRVLATPSTCVQFKPHCTHFTIDAEA
PGWRWLNLDQDGHLETEVKRLNTRKFNPDLDSEGY
>A0A165XQM8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. HI00D65|TrEMBL
MKLSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGES
WQMIMLDSQVVGVPHGRLSDQQLDLLEQKLAEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHSNVRAVLCGHVHQDMNREHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPNGQFLPDFEAAGY
>A0A1W6B5P5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea alhagi|TrEMBL
MDSLLKLPVVSGANIRILQITDTHLFSGKNETLLGVNTWASFNAVLEAIEAEQQPIDLII
ATGDLAQDHSPEAYQHFAEGIARLPAPCVWLPGNHDFQPTMYDTLAQSGIAEAKQVLLGE
HWQLVLLDSQVAGVPHGMLSDYQLEWLDKTLAQTPERHTLVLLHHHPLPSGCTWLDQHSL
RNPHALEAVLQHWPLAKTLICGHIHQEMDVEWHGRRLLAAPSTCVQFKPHCTNFTIDAVA
PGWRWLELNDSGVVQTQVQRLSTRAFTPDLDSEGY
>A0A6S6ZLQ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter kerstersii|TrEMBL
MTRILQFSDTHFGTERKPVVEAALDLARSLNPDLVVLSGDITQRARRAQFAAARKFIERL
SLPVLAVPGNHDIPLFNVFARALNPYGNYKRALGAVLEPVFETPGLLAIGVNTTRPRRRK
DGEISDTQIARVAQRLRQARPGQLRIVVAHHPVRAKVESDLSNLLIGRERALAAWAQAGV
DLILGGHIHLPYVLPLSAAGQPAGWIVQAGTTCSRRVRGSVPNSVNVIRCEEEGGQQVCQ
VERWDYAEGTHAFAPVDKTLVAGS
>A0A5J6QD28|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. C27(2019)|TrEMBL
MEPLDTIPYVTVVQLSDSHLFADVDGRLLGMQTDDSLQQVMSAVIAEQSNIDLLLCTGDI
SQDGSIVSYQRFAETVKTLGAPMRWFAGNHDERLALQQVCAETDWLQAVYDIGAWRIVLL
DSSVANKVYGMLAEDQLTLLEQALASAGERHVLIGLHHHPVPIHSCWMDKIGLHNAAQLL
SIVSRHSNVKAVIWGHVHQEFDQLINGVRWLAAPSTCVQFAPRSDDFAVDDKAPGYRWLR
LYEDGQLQTAVSRVENIDFEIDYSIKGY
>A0A8G2JAD9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter terrestris|TrEMBL
MTLSNCHETQQDWTIIQISDTHLMNQEDLEFVHMNPEHSFHTVIKQIQQQYPNVDAIIHT
GDLAQVPVKETYTRYLAFMQRLGIPFYQIPGNHDNIEIFPFYHNQNQAHAIHFGKWSIVL
LNSAVAGKTDGWIEQAQLQQLDQILSKFQQQYVIVACHHHPFDMQSKWIDQHKLKNTENL
TDILAKHTNVKAVISGHVHQDAWNEWKNIQFFSTPSTCVQFKPLSDDFALDEQAPGFRVL
HLKANGELQTEIYRTEKVQKKINTEISGY
>A0A6I6DYD9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Leclercia sp. 119287|TrEMBL
MESLLNLTVAGGAPVRVLQITDTHLFAKKHETLLGVNTWESYQAVLEAIHAQKRECDLIV
ATGDLAQDQTSAAYQHFAEGIASFNAPCVWLPGNHDFQPSMYSALQDAGISPAKRVHSGD
NWQILLLDSQVFGVPHGELSEFQLEWLEAKLAADPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDQVLMKFPRVNNLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLQSTQFRPDTASEGY
>A0A381G1M0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter amalonaticus|TrEMBL
MESLLNLSLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEGQEYDLIV
ATGDLAQDQTSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKCVMVGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLAAAPERHTLLLLHHHPMPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDSIG
PGWRTLELFADGTLKTDVCRLQGTEFRPDTASEGY
>A0A8E0T118|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Plesiomonas shigelloides|TrEMBL
MESLFQPPVATERVRLLQITDTHLFADEEGALLGINTLQSYHAVLDAIVAEQQIAEQQPV
DLIVATGDLAQDHSLEAYDRFADGISRLGSPCVWLPGNHDFQPAMVDGLRGKGIQPSKQV
LLGDHWQLILLDSQVLGVPHGELSDYQLNWLAARLDAHPERHAAILLHHHPLPSGCTWLD
QHSLRNSHVLDEVLSSRPQAKVVLCGHIHQEMDLNWNGRRLLATPSTCIQFKAHCTNFTL
DQLTPGWRYLDLLPDGRVETQVHRLTDQRFSPDMESEGY
>A0A0M1GIQ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus sp. C1|TrEMBL
MKNTFVYQAEKPIIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNEFDVILA
TGDLVQDSSDEGYARFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLASFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTKVKRIQQAKFLPNMQEEGY
>A0A661G2L7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MLTPAILPFASPEASTSPIHTSTDPVRVLHVTDPHLFADSESSLRGTVTHSTLTQVLAAI
QADDWQADLVAMTGDLIQDDSREAYDRFCELMRPLELPVYCVPGNHDVRDLMRDAVSQPP
FHYCESLYTSNWLITGIDSCIDGDAGGRVNDDEMERLEKILDATAAEHVLICLHHPPLPV
GCKWLDEVGLHNGEEFLSLVSRTGKVRAAIFGHVHQEFFVERDSIKIIGTPATCRQFKPA
SDEFALDDNPPAYRRIELHVDGNVSTELVWLAVE
>A0A7V8V296|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bremerella alba|TrEMBL
MTKFPLPIVLLTAAVFATASQFSQAHEGPDPLARWRFDSQGVVTEAEATTLRARRGPDGT
VLGKHQMLGEKYEEALFLSGKMSGIVLAEDHNEAAKFLPSESLTVSVVVSVDRPEKWGGL
VGVIQDNGSNESGWLLGYDQTTFTFALRGDNGPGKLTYLKGTTKYESGKLYHVVAVYDGK
TMQLYVNGKLDAETTAQSGPIHYPGKAPFMIGAYRDDNEFHSQRGRIRDVVLYDLAAKKG
WVEHDYEHNADLAKLPPVEIHEPLDFVIDPYLQFGTQTTMTVMWRSNRPAMGTLFYGETA
QCPQRIDVADLKTVHEIRIEDLQPETQYFYRTETRLTEEGPPLLSEVATFQTAVHKDTPF
AFAVISDTQGNPTVSGKLAGLAWEQRPSFLLHPGDLVSVGPDDSHWTQHFFPSMNPLIRH
VPFYPVLGNHERNAQYYYDYVSLPSPEYYYTYRFGNAQFFMIDSNRNVDPESEQYKWLEK
TLSESDAAWKFVCHHHPPYSSDENDYGNLWKTNKGTRGDTKARQLVPLYEKYHVDIVWNG
HIHSYERTWPILENKAVNQGGPVYMITGGGGGPLETPGPIRPFFMNTVRRGHHYAMVRIN
GAKLEFQAYDLDNRMFDQMVIEKKTGQDQE
>A0A2J8LTC6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pan troglodytes|TrEMBL
MTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERDLSPRPELRKSRLSWPVSSCRRFDL
ENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASD
LHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAANPAPAKTNNNALGDGPHHTHITD
EEAEAQRSHAGGWAGP
>B2U1E0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A8C0V6R4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyanistes caeruleus|TrEMBL
EEVFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRN
SSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCSQPSINKATIT
GKNNLFIKKSN
>A0A0E8XEI7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia wautersii|TrEMBL
MALPTDSHNTKNYLVGGRQKQGYHLESLFKLPMASGARVRVLQITDTHLFAGEHETLLGV
NTSHSYRAVLDAIIAEQHPFDLVVATGDLAQDHSVAAYQNFAKGISRLPVPCVWLPGNHD
FQPAMVDALAEAGIAPSKQVLAGEHWQILLLDSQVFGVPYGELSDYQLEWMERCLIAYPE
RYTLILLHHHPMPSGCTWLDQHSLRNAHMLAAILTRYPRVTTLLCGHIHQDLDLDWYGKR
LLASPSTCVQFKPHCTNFTLDAVAPGWRYLDLLPDGGLETEVHRLDSDEFCPDMDSDGY
>A0A8C0V1W2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyanistes caeruleus|TrEMBL
MCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCSQPSINKATITG
KNNLFIKKSN
>A0A5A9Z0N9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pusillimonas sp. ANT_WB101|TrEMBL
MQSSFFVVQISDPHLLADPEGCLLGVNTDHSLRGVIDDIKRREPQIDVVLATGDIAQDGS
VQAYERFLHHASDINAPVYGLPGNHDDGDTLRSVWQARLDPVVELGNWCIVLLDSSVPGS
NSGHLAQSQFDVLQTAAMQAHDRHILVAVHHNPVPTGSPWLDSMTIDNGDALFKMLERLP
NVRCLLWGHIHQEYDDVHQYSPTHGLRLLASPSTCVQFKPYSKTFELDTVSPAYRWLRLH
ANGDVETGVQRVEGLGVYPDLGGTGY
>A0A7G9BVD1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella typhimurium|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVLLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2H5WBJ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR12|TrEMBL
MVTIAHISDPHVGSPYFVPNMMQRVIAELNELRPDVVINTGDLTNEGYRQEYKTWLAYAE
RIEAPMHTVPGNHDARNVGYLHFEELIGPRYWSVEVQGVRIVGVDSSEPDLNEGMVGRMH
YGWIQQQFAQPAEVKIFVLHHHLLPIPGTGRERNIAIDAGDVLEELVTAGVNIVLSGHKH
VPYVWHLENLWIANAGTVASLRVRGYTKPCYNVVEIDGDEVRIMRRYPFGGASMIAHFSL
STDEQYYREFEPPVQQRATAPLGD
>A0A2P8VH02|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Siccibacter turicensis|TrEMBL
MESLLNLTVADGATVRILQITDTHLFASKGETLLGVNTWESFQAVLAAIHQAQRECDLIV
ATGDLAQDHSAEAYQLFAESIASLASPCVWLPGNHDFQPAMYSALQDAGISPAKRVLVND
VWQILLLDSQVFGVPHGELSEYQLEWLERKLTDWGDRQTLLLLHHHPLPSGCGWLDQHSL
RNAGDLDDVLSRFPNVKHLLCGHIHQELDLDWNGRRILATPSTCVQFKPHCANFTLDTIA
PGWRWLHLHPDGTLTTEVCRLEGQAFRPDIASEGY
>A0A6F9ALY0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Coregonus sp. 'balchen'|TrEMBL
MDSDILSSCSAAPDTFSHESSLLSLFSPQYVSCDDNASIFDVENGLPVGHSPVDPQASPS
SGLVLQANYPHSQRRESFLYRTDSDFDLSPKAIHGEDMIVTPFAQVLASLRTVRSNFTVI
THLQDRPNRWPSGSNPPSMPTHTKPSIPEEPYQKLAMETLEELDWCLDQLETLQTRHSVS
EMASNK
>A0A3E2KSJ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter gillenii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQCILDAIHAESTDFDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPSGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIS
PGWRTLELFADGSLHTQVCRLPGIRFHPDTASEGY
>A0A091MCC9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acanthisitta chloris|TrEMBL
VLQGTFSHGQRRESFLYRSDSDYDLSPKGMSRNSSIASDLHGEDMIVTPFAQVLASLRTV
RSNLTHLQDR
>A0A6J5GV55|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia caffeinilytica|TrEMBL
MTCIAQISDIHVRPKGELYQDLVDSNAMLARAIAALNAVRPAPDLVIVTGDLVDEGRPAE
YAMVRELLAALTPPYIVMPGNHDNRDHLQEAFADHPWLPRSGPLHFARDVGTVRLIALDT
SVPDEHHGDA
>A0A5J1M8K9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Isangi|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A7L6UBX5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. RHB35-C17|TrEMBL
MESLLNLSLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEGQEYDLIV
ATGDLAQDQTSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKCVMVGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLAAAPERHTLLLLHHHPMPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDSIG
PGWRTLELFADGTLKTDVCRLQGTEFRPDTASEGY
>A0A5N4WD12|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter tandoii|TrEMBL
MTLKQPHEQPQSWTIIQISDTHLMNQDDLEFVHMNPEQSFHRVMAQIQHEYPHAHALIHT
GDLAQVPVSETYQRYLAFMQTTGFQYYQVPGNHDSEEFFPFHDQQNKVHAIPIGNWCLVL
LNSAVKGKIDGWINTEQLKQLDQILNLHAEQSILIACHHHPFEMQSRWIDQHILKNTEHL
TDVLAKHSNVKLVLCGHVHQASENQWHGIHFLSTPSTCVQFKPHSDDFALDDEAPGYRVV
QLKANGEFTTQVHRTQPIQKKINIEITGY
>F5NZF1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella flexneri K-227|TrEMBL
MESLLTLPLAGEARGRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A6G6JPM8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea stewartii|TrEMBL
MDSLLTLPATTESEVRILQVTDTHLFAGKHESLLGVNTWASYDAVLDAIIAQQRDYDLIV
ATGDLSQDHSVEAYQHFVEGISRLPKPCVWLPGNHDFQPAMVDTLAEAGINAHKHVLLGE
HWQVVLLDSQVFGVPHGMLSDYQLEWLNTTLARYPQRHTLVLLHHHPLASGCTWLDQHSL
RNPHQLDAVLQHYPLAKTLVCGHIHQEMDVPWQGRRVLATPSTCVQFKPHCTSFTIDTVA
PGWRWFTLHNDGQLETEVNRLTTQAFRPDLDAEGY
>A0A0L0GQM5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trabulsiella odontotermitis|TrEMBL
MESLLNLPLAGGARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRASQRECDLIV
ATGDLAQDHSSAAYQHFAEGIAGFAAPCVWLPGNHDFQPAMYSTLQDAGISPAKRVLVGD
HWQILLLDSQVFGVPHGELSDFQLEWLEHKLAESAERNTLLLLHHHPLASGCSWLDQHSL
RNAGALDQVLSAYPRVKNLLCGHIHQEMDVAWNGRRMMATPSTCVQFKPHCANFTLDTIA
PGWRWIELHADGTLTTEVCRLEAAQFRPDTASEGY
>A0A5E4SVC6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea pneumonica|TrEMBL
MLLCQITDLHVARPGALACERVDTARALRQAIATIHRWSPRPDAVIATGDLVDTPHPSEY
EVLRECLAELQIPLYLVVGNHDHRAGLRAAFPEHTYLHGGHPGGGDGFVQYRVDIGPVTV
LALDTQSPPGAGGHLCDARLSWLDAQLQACAGRPTIIAMHHPPFDTGIEFMDELGLSSQG
REGFAAVVSRYPHIERVICGHLHRSIQAGVAGAPGVMASTCVSTAHQISLGLAPDAPGSI
TLEPPGFALHLWTPGAGVRTHLAYVGPFEGPYTFEGESVS
>A0A432CVZ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio aquaticus|TrEMBL
MKVTSISPAQDSIKLLQITDTHLFEPLDGSLLSVKTLDSFHAVVAAIAESGASYDAMLAT
GDISQDHTAVSYQHFEQGISPLALPCYWLPGNHDFKPSMHSVLPSSQIQQVEHVLLGDHW
QMVLLDSQVVGVPHGFLSDDQLSMLDEKLTQNPDRHTLVLLHHHPLLVGSRWLDQHSLKE
AESFWNVVEKHSNVKAVVCGHVHQDMNEMHRGVQVMATPSTCVQFKPKSDDFALDTQSPG
WRELDLHNDGSVSTQVKRLASGSFQPDFNSAGY
>Q9CM25|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurella multocida (strain Pm70)|TrEMBL
MFSTYRYDTSAEVFKIIQITDPHLFKDEHGELLGINTFQSFSQVLHEIKASRFDYDLVLA
TGDLVQDSSREGYLHFCEQVKSLEKTVFWIPGNHDFQPKMFEILNQDQGNLNPKKHILLG
KSWQILMLDSQVFGVPHGELSQYQIDWLVAKLKDHPERYTLIVLHHHILPTHSTWLDQHN
LRNAHELAYALAPFDKVKGILHGHIHQEMDANWQGYRVMATPATCIQFKPDHNTFTLDSV
QPGWRELELYSDGRIETRVKRIQDKTFFPNMHEDGY
>A0A4R1KWH8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lonepinella koalarum|TrEMBL
MVECINRDDEQIRFIQITDPHLFKEKTGELLGINTYNSFRQVVNEIQQSETDYQFVLATG
DLVQDSSEEGYLNFCHIIHPLGKPVYWIPGNHDFQPVMRKVFAQQSYIYADKHLLLGDKW
QVLLLDSQVYGVPHGELSQYQLDWLDEKLQEYQEYYSLIVLHHHLLSTNSVWLDQHNLRN
AHELLHILQKYENVRGILHGHIHQQVDAQWNGYQLMCTPATGVQFKPDNNVFTLDTLQPA
WREISLMPDGTIETQVHRIQQAKFLPNMHELGY
>A0A428LNX5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter huaxiensis|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQEAGISPAKCVFVGD
HWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLVNFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLSGAKFRPDTASEGY
>A0A1C2PND1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter pittii|TrEMBL
MTFQVSTLSQKDHVIIQITDTHLLEYPHLEFVGMNPEESFHAIIQQILNKHPEIDAIIHT
GDLAQAPTPITYNRYIQYMQTLGLPFFQTLGNHDNVDHFPLHKENHQEPVVICLGNWRVI
LLNSAVKGHIDGHLSAEQLDSLTNLLEEYADNPILLACHHHPFAMKSKWIDHHKLQNSNA
LLTALTPFKNVKALVCGHVHQDSINTWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLKNDGSFETEVFRLENFQGHINTDISGY
>A0A7I6TW47|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella sp. WP7-S18-ESBL-04|TrEMBL
MESLLNLPLAGGASVRVLQITDTHLFAEKNETLLGVNTWESYHAVLQAIHASARDVDLVV
ATGDLAQDHSAAAYQHFAEGIASFTAPCVWLPGNHDFQPSMYSTLQDAGISPAKRVLVGE
HWQILLLDSQVFGVPHGELSDFQLEWLEKRLAEAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAASLDTVLVRYPRVKHLLCGHIHQELDVEWNGRRIMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHADGSLTTDVCRLAGVKFHPDTASEGY
>A0A221UX29|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arenibacter algicola|TrEMBL
MCSDVHLPTMHDSEYRISTFIDSMANAKPDFIIELGDFGTPAEKYASLFDIWNSFPGEKY
HVIGNHEMDGGFSRNEALAYRDMKSGHYTFNKNNFTFIVLDGNDPKSEDDRGYKQFIGAS
QLQWLKDTLSKAIFPVVIFSHQGLVRLPNTEKEPYGLENDSEVRGILEEHNANNSKNRVI
ACFNGHAHYDDAQEINDIWYITINSMAYKWMDEAYTQIRYSNEIDKEFKWIKFTAPYKEP
LFTIVEISSEGYIKINGKKSEWVGPSPWELGYPESLRKYVKPEISKRDLRF
>A0A7U9WT74|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lachnospiraceae bacterium|TrEMBL
MQFRFDLGASFQPETGFFVKNHPAWMADFHFYQVTAGDEVICSDSAYCFCIASYSPEIED
RLIYTYCYQQEENWSSYNKDFVPDNVKCSSSVIPQDGWIRIAVRRVDGQMLTEGDADTAE
KAFVLIRKKRFYQEKEFYQQEIEQTVQAVMEKRGKSCLVFGLMTDSHYVINGGWEDSISN
LRTVNHRTGFDAMIHLGDLTDGMVPLAITREYVEKVMEDLYSLKVPVYLALGNHDSNYFN
NNPEWMDEQTQSSLYLDRREPWYYVDFEKQKLRCLFLHSFNHREKVRYGFPAQEVDWVKK
VLAETPESYSILVFSHVPLLAEMHFWSKEIRNSGEMLDVLEGYASRGGRVIAYVHGHNHA
DQICCEKKFPIVSVGCAKCEDFKDKKPDGAVTYDRKMGTVTQELWDVMVVDVEEGKIEFV
RFGAGEDREVC
>A0A221V159|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arenibacter algicola|TrEMBL
MEDKKKDLGGRRKFLLQSGLAAVAIPFTQISCQNSNEKEAIEENGDSFEFAFLTDIHIKP
EMNAPKGFQMAIDKVNELNPDFVITGGDLVYDTMRGNFEQSESLFALYKDMSKGFNMPVY
NCIGNHDLFAIYEESPESEDHPDYKYGMWERHFGDTYYSFDHKGWHFITLNSLDVTENKR
YQGVFHEKQLEWLKEDIAKLDKSTPIIITTHIPMICTYSQLNGSEGSRTVNNASDVFKIL
EGHNLKLVLQGHIHWKEYGFINDRFHFLTGGSIAGNGWKGRRHNTKEGFVKIKISGNDFS
WEYVDHGWESERLKLAENNI
>A0A679IXK6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium bullatum|TrEMBL
MTAPGLRLWVFSDLHQDWKENAWDPAAHAPAGGFDVAVVAGDVHMPLVRALDWLGDHLSG
VPVVYVPGNHDFWWDRGEERYTIHDQLTRGRERADALGIHLLLDDAVIIDGVRFAGGTLW
TDFRLGSFNLNHGIRTAQGRGGMVDYRRIRTGPRSRNRIKPEEVLAMHRVTRGFIENTLA
VSHPGPTVVVTHHAPHPASLPRSDADLRWCDASDLTDVILDQGPDVWVHGHVHYASDYRV
GRTRVVCNARGHSDERTRFRHGLVVEVAHYIP
>A0A8C9HDV0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Piliocolobus tephrosceles|TrEMBL
MAQQTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISP
RNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVH
SQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALT
NLQDRAPSKRSPMCNQPSINKATITGSWMELNPYTLLDM
>A0A376EWC0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cronobacter universalis NCTC 9529|TrEMBL
MESLLNLPVAGGASVRILQITDTHLFAGKNDTLLGINTWESYQAVLSELHAEQRECDLIV
ATGDLAQDHTPEAYEHFAAGIASLPAPCVWLPGNHDFQPAMYSTLQDAGISPAKRVFAGD
RWQVLLLDSQVFGVPHGELSDYQLEWLERMLQAAPERHTLLLLHHHPLPSGCGWLDQHSL
RNAQALDDVLNRYPQVKHLLCGHIHQELDLDWNGRRLMATPSTCVQFKPHCAGFTLDTVA
PGWRWLNLHPDGSLTTEVCRLEGAQFRPDTASEGY
>A0A1U7CL67|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paludisphaera borealis|TrEMBL
MKVVHLSDIHVWRYTWNVGQLVGVRAWWMLALLRGRAHQFQLERVDEVVARVRSLNPDHV
LITGDLTTSALPDEFADAKRHLAPLMADRERITILPGNHDRATRRSSTTNRFESAFGLYM
PRLTFPWLRRLDDETAILGLDATRFHYTPRGRIPTAQLDQARALLTDAPGRPRRLIVASH
YPIAAPPPYERELAAKRLENADELAAWLARVGPHIFCCGHVHAAWAFRPRELPDQLCLNA
GAPLYRDPAALQPPGFLEIDLDADRVKVVHQAWDGTEWKPIVMVDERVFGKA
>A0A7L9GKI4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas taiwanensis|TrEMBL
MSPPDQSRPVHVVQLTDAHLFADPAGSMLGLKTRDSLRHVVAQVRREQPLVDLLLCTGDL
SQDASVASYEAFRELTAPFAVPTRWLPGNHDEAQVMAQVAPELVQAVTDIGAWRVVMLNT
AVHGATHGFLQDDQLAVLEAALKEAGERHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDI
VEGYPQVRALLWGHVHQEWDEVREGRRLLATPSTCIQFAARSEDFQVSEEHPGYRWLRLH
ADGRLETGVERALDFEVQLDFDSPGY
>A0A131YJV0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rhipicephalus appendiculatus|TrEMBL
MGCTQSAIQRRAGGRAGRGGPATPVPTAAGVPPSASDLSAATNNSASNNRCRAPPSASES
QPQHRNSRPQCLEGARPLFRRATNWEVVTERNVPLFAVLDGAPDDGRKGTVALKFGSMYL
TVPSVKVMFVFGKEDAQYNALKWAADKMHYECTLSSTSEAAIDNYLNGQPHLVFVDARSK
STIDPVTLCRTLRGFRGSQFTCIIAVVKKGLADKEEAAVIPLLKCGYNRWFAETCSLGVC
LNEMIQIEHNDLINLWKLRASEALFSALHYARDGVIVTGAAHEIQYMNRAAEKLVGYSVE
EMLGVDAQELHRTDSLKTEVATTICTQLKKGKEWEGTLFHKRKSGECIPMWSKIAPVEIH
TGKSDHVVYIKECPFFLEKPFSPDAVGMNRRQSFAKFHAMTLEAPITKVINMLVSTQENS
SAMVAQALDRVIEILRSTELYNPQLGVGQGKSEDQMTSDLVTGLINTGQKPTGVRRLSHE
TSLMKVNVVNATASSGVLPSLQTAPSKIKDLLENDVKWEFDIIELETLTGRRPLIWLGLS
IFSKLNVHTSLECDDATIRNWLQLVESHYLDNPYHNSTHAGDVMQATAYFLLKLRKKDIF
DPLDEAICLISAVVHDIDHPGKSSAFLCNSDHELAILYNDRSVLESHHAAFAFKLTLSDE
KVNIFQKLDRDVYRSVRLSIIDMVLATEMTKHFEHLSKFLNAFQKPMQEEEGFEAEPLQE
HGESASLRSAENIILIKRMLIKCSDVSNPARPINLCIQWAHRIAEEYCAQTDEEKRRGLT
VVMPAFDRATCSIPNSQTGFINYFVRDMFRAWSDFGEFPELMEYIEKNYIYWKDKEPSSS
QQGNR
>A0A7J0A1Q5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacteroides acidifaciens|TrEMBL
MRKSLYTLLSFLLLSGCGMTDYHPYDVHISGETNVNAHNIEKIEANCKGKTKLRFVTMGD
SQRWYDETEEFVKEINKRDDIDFVIHGGDMSDFGVTKEFLWQRDIMNGLKVPYVVLIGNH
DCLGTGEETYKAVFGPTNFSFIAGNVKFVCLNTNALEYDYSEPVPNFTFMEQEIKDRRDK
FEKTVISMHARPYTDVFNDNVAKVFHRYVTEYPGIQFCTAAHTHHHRDDVIFDDGIHYIT
SDCMDCRSYLVFTITPEKYEYELVKY
>A0A060Z059|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oncorhynchus mykiss|TrEMBL
MLIFCSSPVSYLTKCFFLLLHGEDMIVTPFAQVLASLRTVRSNFAYITHLQDRPNRRPSG
SNPPSIPTHTKSSITDEPYQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKVSCVALN
>A0A4V2LUT4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter quasihormaechei|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFVGD
QWQILLLDSQVFGVPHGELSDYQLDWLETKLAAEPDRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLAKFPRVKHLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLAGAEFRPDTASEGY
>A0A0H3FB80|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rahnella sp. (strain Y9602)|TrEMBL
MESLFTLPLVNGAKVRILQITDTHLFAGEDETLLGVNTFNSYRAVLDAIKAQQREVDIIA
ATGDLAQDQSVEAYHQFARGISELTAPCVWLPGNHDFQPAMVNALQDAGISPSKHVLLGE
HWQIILLDTQVFGVPHGELSEYQLEWMERCLNAYPDRFTLLMLHHHPLPSGCTWLDQHSL
RNAHMLANTLVNYPKVNTLLCGHIHQELDLDWYGRRLYATPSTCVQFKPHCTNFTIDTVA
PGWRYLDLYPDGRVETEVFRLETNEFHPDTESDGYE
>A0A2D4GV78|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micrurus corallinus|TrEMBL
AALTTLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSV
SEMASNKVGTPVCFHLSNIPPPHPAPSVLLCLALFSPFSDDSEGKLTS
>A0A735AS00|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Rough O:-:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5E4WXN3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea soli|TrEMBL
MCATLRVAVLSDLHYTELAHGPCLAQASAAGGLDLMENLIKRFEALEKPSADVLLCPGDI
TDRANPKAFAAGWAQINRLGKALGVKRVAAVTGNHEVQSRADKKLIEPGNAEHAIDPLEF
LVHEPGYPATFALPHQKWVYWGRGYEILYDDESIIVLVNSCHYHVTLQDNEFERGRISDI
ALEELRSDLKHLAADRSFRMLVVHHPPLPHEEPGLELGRTPMHNGTALMAALKETGLDWL
VIHGHKHHHRLTRGDGEVYQPFVFGAASFGAMLYGDMASRTRNQFYIVTLETAKDELDVD
RLSGNIQALHWTNSGWEETADTTRGLPSGCGFTWRPVELSGLAAQVRSRLQASGGQFLEW
SEVVDSLPLLRFLSPGQMSALKDQMTRAKISLIDDGSLFPRQLCISAS
>A0A2I8NLR4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Leclercia sp. LSNIH1|TrEMBL
MESLLNLTVAGGAPVRVLQITDTHLFANKHETLLGVNTWESYQAVLEAIHGQKRECDLIV
ATGDLAQDQTAAAYQHFAEGTASFHAPCVWLPGNHDFQPAMYSALQDSGISPAKRVYAGD
HWQILLLDSQVFGVPHGELSDFQLEWLEAKLAAEPERNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDQVLEKFPRVKHLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLEGTRFRPDTASEGY
>D0Z073|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium damselae subsp. damselae CIP 102761|TrEMBL
MLTYSLPPRQSDSVVLLQITDTHLFANDAGSLLGVATKDSFHAVLAAIDHQARPFDAIIA
TGDISQDHSTESYQHFAQGIARWQQPCFWLPGNHDYQPSMKAVLPSPQIKPCEQVLLGEH
WQMILLDSQVPGVPHGELRAEQLEMLDRALAAHSERHALVLLHHHPLAAGSAWLDQHQLH
NADDFWQVLARYPAKVKSVLCGHIHQELDCMRQGVRVLATPSTCIQFLPDSDDFALDSKA
PGWRYLELTPQGDVHTQIHRLANDQFAPDLNSAGY
>R0KQ34|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anas platyrhynchos|TrEMBL
SALKNAIFVCVLLPCQFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQ
KDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVKTEKEDHLAKELEDLNKWGLNIF
NVARYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAAD
VAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDES
VLENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMV
ETKKVTSSGVLLLDNYTDRIQV
>A0A8F7QHI4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter johnsonii|TrEMBL
MPLSNHTDSSSGWTIVQISDTHLMDQDDLEFAAMNPEQSFHAVIQHMRQHLPDIDAIIHT
GDLAQVPVSETYDRYLRFMQTLNLPHFQIPGNHDDTAIFPFHRQQDRAHMLSFGNWRLIL
LNSAVEGKVDGWVAQEQLEQLDQMLSEQADQHIIIACHHHPFAMQSFWIDQHKLKNADHL
LDVIAKHQNVKAVLYGHVHQDSRNERHGVQFLSTPSTSVQFKPHSDSFALDESMPGYRVL
NLKENGEFSTHVIRVKINQPKINVEISGY
>A0A077MWJ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus bovienii str. feltiae Florida|TrEMBL
MESLLKVPVAEGATARILQITDTHLFASKGDALLGINTYRSYHAVLDAILEQSIDIDLIV
ATGDLVQDQTIGAYQNFAEGIARLPVPCVWLPGNHDYQPAMVDVLAAAGISPSKQILIGQ
HWQLVMLDSQVQGVPHGELTDYQLEWLQKCLDEHNDRNTIVMLHHHPVPSGCTWLDQHSL
RNAPALAESLKDKRQVKAILCGHIHQELDKMWNSIRVMATPSTCMQFKPHCTNFMLDTVA
PGWRYLELSVAGNREARLQTQVHRLKSNEFCPDLDSDGY
>A0A8D5AR16|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio alfacsensis|TrEMBL
MQSSSDSIKLLQITDTHLFAADEGSLLSVRTADSFYAVVQEILKRQVQFEYILATGDISQ
DHSAESYHRFADGITPLGKDCFWLPGNHDYKPNMSSVLPSSQIQTVEHLYLGDHWQVILL
DSQVVGVPHGRLSDQQLSLLEEKLAENANRHTLVLLHHHPLLVGSAWLDQHTLKDADAFW
QVVDRFDNVKGIVCGHVHQDMNVVHHGIRVMATPSTCVQFKPNSDDFGLDTLSPGWREIE
LHQSGDITTQVNRLSEGQFQPDFTSNGY
>A0A2N7D9F8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. 10N.286.49.B3|TrEMBL
MKRSSSLDADNESIKLLQITDTHLFAPEDGSLLSVRTAESFRAVVKAIVQDGFPFEAILA
TGDISQDHSQASYQKFEAGIMPLEKPCFWLPGNHDFRPNMSSILPSPQIQCVEHALLGDH
WQLIMLDSQVVGVPHGRLSDQQLDLLEQLLEENPQRYTLILLHHHPLLVGSAWLDQHTLK
DADQFWKIVDQYDQVQSVVCGHVHQDMDRLHNGVRVIATPSTCVQFKAHSDDFALDTLPP
GWREIELLANGDIITKVKRLPDGHFIPDFNAQGY
>A0A7Z7IRQ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mycobacterium simulans|TrEMBL
MAPPVHRLRAAEHPRPDYVLLHISDTHLIAGDRPLYGAVNADDRLGDLLQQLNHSGLRPD
AIVFTGDLADKGEPEAYRKLRDLVEPFAAELGAELVWVMGNHDNRAELRKFLLDEAPSMA
PLDRVRMIDGLRVITLDTSVPGHHHGEVRAAQLDWLARELATSAPDGTILALHHPPIPSV
LDMAVTVELRDQASLGRVLKGSDVRAILAGHLHYSTNATFVGIPVSVASATCYTQDLTVA
AGGTRGRDGAQGCNLVHVYQDTVVHSVIPLGGGQTVGTFVSPAQAKRNITESGIFIEPSR
RDSLFKHPPMVLTRSAPQSPAG
>A0A068Z164|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia symbiotica|TrEMBL
MESLFKLPVASGNTARILQITDTHLFADKHETLLGINTYRSYHAVLDAIQAQRRELDLIV
ATGDLAQDHSLAAYQHFAEGIFQLPAPCVWLPGNHDYQPAMVDALTTAGIEPSKQVLLGD
SWQVILLDSQVYGVPHGELSEYQLEWMARCLQTHPERYTLLLLHHHPMPCGCTWLDQHSL
RNPHMLATTLLRYPKVTTLVCGHIHQDLDLEWQGRCLLTTPSTCVQFKPHSTHFTIDDVS
PGWRYLDLLPDGRVETQVYRLENNDFRPDMDSDGY
>A0A6M4XFZ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sp. 2692-1|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVRANDHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRIASQVWRLPVGQFVPDPNATGY
>A0A8J7Z332|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Myxacorys almedinensis A|TrEMBL
MAHSPSLRIVQVSDTHLFATEDRHLLGLSTLRSLEALLESLRQLAPLPDLFLLTGDLSQD
GTAASYQHLQARFNSLEVPIYWLPGNHDCVEMMERSLTHPLFKADKSFQGGGWRLILLNS
QAPGCVHGMLSPSALDELKQQLQQFPHTPTLVSMHHPPLEVESEWIDGSRLQNASEFFDI
VDRYSQIKLVVFGHVHQEFYYQRGTVSYLGTPSTCVQFEPKSTEFALGHQEPGFRLIELY
KDGTWATQVQRIHYMGKLDLAATGY
>A0A2T0AMM6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clostridium thermopalmarium DSM 5974|TrEMBL
MKYRWIHLSDIHFAYKNYQSNRLRGKLFDKIAEIVKQDKVNFLFITGDITDKDAEYDEDL
YKFITELLRVTELDEKHLFFVPGNHDVSRKSKERIEKIVQIREAGDKGLDVVNDLSDDSI
EMLLSAQQKFFTLYEHIKKEKYPVKDIHFVREVDGAKIIHFNTAWLCGMDGEEGRLFLGS
NKLYSCLKDAGLKADDLNIAIGHHSFECFHRMEQDQLKGFMKDYNIDFYLSGHLHEAMIN
YNSHIDTHFCVCRQMRSDNFDAGGLAIGNIDTETGNNNIQFHAWNQRGYWTWDTEVGHEA
PYGIYSFNTAKFPATKYRENPVVVIHKTMNTPINQQKLLNDMGFGKVPVYHYPYSNIEIS
TQEEWMEHKSNTDSFINGVISRLKDNVVHIFPLSQIPLLIEMGYMLQNDNDNIKIYQFDE
NGKWVLDSENAEKIPVTISYIENNPKTKKLIVVLEISSTIKNEDIDVYVSTSEHSILRFT
IDNPLRYKVIYESQVKDIKSKFRSETEKHIYDYDEIHLFAAMPAGLSVEVGRCILRSMWP
KVYLYNHRRQNDPRYQFAFSIN
>A0A8B6J0K3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella africana|TrEMBL
MLLAHISDTHFRSRGEKLYDFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLLPGNHDDKAHFLEHLHPLCPLLGNDPQNMRYAVDDFATRLLFID
SSRAGTSKGWLTDETISWLEAQLFEGGDKPATVFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTQPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A2S9SI65|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNAFVYQTEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENHEFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLVPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTQVKRIQQAEFLPNMQEEGY
>U6DN59|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Neovison vison|TrEMBL
MKKSRSVMAVTADDNVKDYLECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQS
ERARTPEGDGISRPTTLPLTTLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVL
HATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVR
NNFTVLTNLHGTSSKRSPAAASQPPVSRVNPQEESYQKL
>A0A672KD60|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sinocyclocheilus grahami|TrEMBL
MLNRELTHLSEMSRSGNQVSEYISSTFLDKQHDVEMPSPQTQKEKEKKKKPMCQISGVKK
LMHSTSLTNSNIPRFGVKTETEDSLAKELEDINKWGLNVFKVTEFSGNRPLTVMMYTIFQ
ERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSMPALEAVFTD
LEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCD
IFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRI
QVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFIQGDRERERGMEISPMCDKHNASVEN
NISNYGFL
>A0A5X7TLM5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enteritidis|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQHEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A762GN34|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDVDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETKVHRLQDTRFRPDTASEGY
>A0A5H7LC98|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella moscow|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A663AHH7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella quasipneumoniae subsp. similipneumoniae|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVFLGD
HWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A226PJL3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Colinus virginianus|TrEMBL
MTKQGITDGAYSLIPGTSTPSSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRA
PSKRSPMCNQPSINKATITGIQSNRLDRIGSFGSLEQKNEKMRREEKRREEKRREEKRRE
EKRREEKRREEKRREENDSKTFYF
>A0A7U9CUN9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pneumoniae subsp. pneumoniae KpQ3|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A3Q3LXC1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mastacembelus armatus|TrEMBL
MELFLSFAVILPQFKRMLNRELSHLSEMSRSGNQVSEYISSTFLDKQNEVEIPSPTLKDK
PMSHISGVRKLSHSSSLSSTSMPRFGVNTDHEDELAKELEDLDKWSFNIFRVAEFSNNRP
LSCIMYAIFQERELLKTFRIPVDTFVTYVMTLEDHYHGNVAYHNSLHAADVTQSTHVLLS
TPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVG
FKLLHQENCDIFQNLTKRQRQSLRKLVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGV
LLLDHYTERIQVLRNMVHCADLSNPTKPLPLYRQWTERIMEEFFRQGDKERERGMEISAM
CDKHTASVEKSQVLLDFFPLFSYLVFLLW
>A0A3L9M3I7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. 2JN-4|TrEMBL
MTFQVSTSSQQDFVMIQITDTHLLEYPHLEFVGMQPELSFRAVIELMREQHPQIDLIVHT
GDLAQTPTPVTYQRYIQHMQSLGIPFFHTPGNHDDVAHFPFHQADQTQPTIIELGKWCII
LLNSAQPQRIDGKIADIQLKQLAELLPQLQDRYVIIACHHHPFAMQSAWIDQHKLKNSSD
LLEIIQPFSNIKAIVCGHVHQDSIQTWQGIEFLSTPSTCIQFKPKSDKFALDEEHPGYRY
ICLKANGELETQVYRLSTSERLMSSEVLGYD
>A0A6L9JLT9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus luminescens subsp. laumondii|TrEMBL
MESQFELPVVEGTTAKILQITDTHLFASKEDTLLGINTYRSYQAVLDAILKQNADIDLIV
ATGDLVQDQSLEAYRHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGK
HWQLLMLDSQVQGVPHGELSEYQLEWMKNCLDRHPERYAVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQSYSRVKAMLCGHIHQEMDLDWNGIRMMATPSTCLQFKPHCTNFMLDTVA
PGWRYLELSVADNGEFGLTTQVYRLASNEFCPDLDSDGY
>A0A7Y8USW4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas allii|TrEMBL
MSSVSTVSPDAPALLVQLSDSHLFAEADGTLLGMNTRDSLHRVIELVRAQQPRIDLVLVT
GDLSQDGTLESYQQFRDMTAPIGAPTRWIPGNHDEPQIMAHAAVHSDLLEPVVDVGQWRI
TLLDSAVPGSVPGYLQDSQLQLLAQALSEAPNRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDHERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERVQGFEFTVDYGSNGY
>A0A2K5YDP1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mandrillus leucophaeus|TrEMBL
PQGRSVRHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPTNKRSPLGGPTPVCKATLSE
ETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVS
EYISTTFLDKQNEVEIPSPTMKEREKPQAPRPRPSQPPPPPVPHLQPMSQITGVKKLMHS
NSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDL
LKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDSELALMYND
ESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKT
MVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGD
RERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDW
YYSAIRQSPSPPPEEESRGPGHPPPPDKFQFELTLEEEEEEEISMAPIPCTAQEALTAQG
LSVAEEALDTTMAREASPAQESLDVMAQDESLEAELEEVYLTQQAQSTGSAPVAQDEFSS
QEESVVAVSQSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRA
CSACTGTSGEDTSALPAPGGGGSGGDPT
>A0A3A5K4X7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Buttiauxella izardii|TrEMBL
MESLLNLPVAGGGQIRILQITDTHLFSGKDETLLGINTWMSYQAVIDAILAEQRHYDLIV
ATGDLAQDHSAEAYQHFVEGIAEIPAPCVWLPGNHDFQPAMFSSLLEAGISPAKQVFLGD
NWQILMLDSQVFGVPHGELSDYQLDWLERKLADAPDRHTLLLLHHHPVPAGCSWLDQHSL
RNAAELDNVLQKFPKVKTLVCGHIHQELDLDWNGRRMLATPSTCVQFKPHCANFTLDTIE
PGWRWLELHPNGDVTTEVCRLKGAVFNPDTASEGY
>A0A2T3HYX4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium aquimaris|TrEMBL
MQTYSLPQSNPDSVVLLQITDTHLFANGSGSLLGVATKDSFHAVLNGVDTAARHFDAIVA
TGDISQDHTPYSYQRFADGISRWSQPCFWLPGNHDFQPTMQSILPSEQIKPHQQVLVGEH
WQMILLDSQVQGVPHGEVSAAQLALLETALARYPDRYALILLHHHPLEAGSAWLDQHQLH
NNHQLWNVIDKYPQVKAVLCGHIHQNLDRIYHGVRVLATPSTCIQFMPDSDDFALDDNNP
GWRYLELTHDGRIITSVHRVDGDQFKPKLDAEGY
>A0A6S6Z9U5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter pestifer|TrEMBL
MPRAHSLARRHDAPAMLVQLTDSHLFGEPDTAMLGVNTDASLRAVLRQIEADGKHPDLLL
ATGDLSQDGEATSYQRFAHILGDAAALSRAQIRCLPGNHDQPSVLRQELPQWSAPVTDVG
AWRIVALDTTVPGSNAGHLPDSQLDMLEAALAEAPGRHTLVAMHHNPMQIDSHWHDSMMI
DNPQALFKRLSRWPQARVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNMA
PGYRWIKLYQDGSMATGVRRVQDALWHTALAPDDAQAA
>A0A3G8JTW4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gordonia insulae|TrEMBL
MNDGGPGGIRMSEYPHPSHLILHLSDTHLVGGPGPLYGAVDSEVTLRQILAEVEASHARP
NALLFTGDLADRGEAVAYRKLRSIVDGVADSIGAQVIWAIGNHDDRANFRTELLDEPPSV
APVDRVYDVDGLRIITLDTSVPGHHHGEISDEQLAWLAAELSVPAQHGSILAMHHPPVPC
VLDLAVLVELRDQDRLADVVRGSDVRSILAGHLHYSTTAMFAGIPVSVASATCYTQDLTG
PAGALRGRNGAQGFNLVHVYPETVVHSVAPVGDYDTVGEYVSSAETRRRLREGGVRIPGP
ETLTLRR
>E5B1A2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia amylovora ATCC BAA-2158|TrEMBL
MDSLLKLPVASGSRVRILQITDTHLFAGKDETLLGVNTWASFDAVLEAVAAEQRHYDLIV
ATGDLAQDHSVEAYQHFAEGIARLSAPCVWLPGNHDYQPTMFSTLGASSIADQKQVLIGD
HWQAMLLDSQVFGVPHGELSEYQLDWLDRAMAAEPQRHTLILLHHHPLPSGCSWLDQHSL
RNPHMLDAVLQRYPRAKTLLCGHIHQELDLNWHGRRVLATPSTCVQFKPHCTNFTIDAEA
PGWRWLDLAADGHLETEVKRLNTRMFNPDLDSEGY
>A0A1B3JIP2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurellaceae bacterium NI1060|TrEMBL
MRNTFVYRTEKSIVKLLQITDPHLFKDEKNELLGVNTQASFAQVLKEIQQDNTEFDVILA
TGDLVQDSSDEGYQRFVKMVKPFGLPVFWIPGNHDFQPKMVENLNQPPMEKAKHILLGEH
WQVLLLDSQVYGVPHGELSQHQLGLLKATLEQYPERYTLIVFHHHLVPTNSAWLDQHNLR
NSHDLFDVLAPFKNVKAILYGHIHQQVDSRWQDYQVMATPSTCIQFKADSQYFALDKIQP
GWREIALYPDGSITTQVKRIQQTMFLPNMQEEGY
>A0A3M0JZB9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hirundo rustica rustica|TrEMBL
MDLLKQAQKRPQSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDY
DLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCS
QPSINKATITEALPLALTDSALACGGFILESCLELDLSEVEEASGSNPATLPATKTWTCK
PK
>A0A0S7FFZ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
MSIILKPRSRSTSSLKNTEGICFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDR
ASNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFK
RMLNRELTHLSEMSRSGNQVSESSSMSEE
>A0A0S7HXU0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
KHRGYSDTDRHHHRHMERSDAVDTSDRPGLKKSRMSWPSSFHGTTNTSIGNCVGNKRFDS
ENGPSPGRSPMDSQASPGLVLHPSFPQSQRRESFLYRSDSDYDTSPKTMSRNSSINSEGH
AEDMIVTPFAQVLASLRTVRSNFTILANVTTPTNKRSPVTSQPTVPQATLSGMLSAN
>A0A7C6RVL8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xanthomonadaceae bacterium|TrEMBL
MPTAAAPLRIVQITDFHLKAKPGSRLWGVDVDAGLNAVLAHIQDRNPAPDFILATGDLVG
DEPEAYGRLRQVLESLGLPVYCLPGNHDFPAVMGRVLRDGLVRWERHLTAGNWQLVLLDS
SFPGTPDGHLASGELALLDTALAVHPELHTLVCLHHNPLPVGTVWLDTMTVGNGAALFSV
LARHPQARAVVWGHIHGEYTGQWGDIQLFATPATCVQFKPNTPEPLVDELPPGYRWFELY
PDGGLTTGVERVEPLTRSIALTRRVPVA
>A0A7Y4AV27|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio anguillarum|TrEMBL
MNVSPTLDNSDSIKLLQITDTHLFAPDDGSLLSVNTVDSFHAIVAEICAQRVEFDAILAT
GDISQDHSAESYLRFSRGISSLEKTCFWLPGNHDFKPNMGAVFPSEQIQQSEHVLLGEHW
QMVMLDSQVVGVPHGRLSDQQLALLDEKLSTHHQRHTLIVLHHHPLLVGSAWLDQHSLKD
SDAFWNIVTQHRNVKAVLCGHVHQNMDKLHHGVRVMATPSTCVQFKPNSDDFALDRTSPG
WRELTLSADGQIETQVKRLANGAFQPDFNANGY
>A0A377PBZ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hafnia alvei|TrEMBL
MESLFQLTVARGAPVRILQITDTHLFAGEHETLLGVNTYRSYHAVLEAIHAQSRPYDIVV
ATGDLAQDHSVAAYQHFAKGIATLNKTCLWLPGNHYFQPAMVDTLADAGVSPAKHMLLGD
HWQIILLDSQVFGVPHGELSEYQLEWLDRTLSLYPARHSLILLHHHPLPSGCTWLDQHSL
RNAHMLGEILQHHPLAKTLLCGHIHQDLDLEWQGRRLLATPSTCIQFKPLCTNFTIDTLS
PGWRYLDLHPDGTLTTELHRLEGTEFRPDLDSDGY
>A0A6J1Q1Y5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Temnothorax curvispinosus|TrEMBL
MGCKISILECMRGKVEQEKSISSATSSSLVTSGKTDALDIVAEKDEKTPFQDSTLDENGD
YLTIKGPQDLSNYLLTTNVPSIVKILLVFSKDDPQLDILANTARRLGWSVSVAKDAEKAI
ELFQNRAHELVIIDHRGHHAAEGDAICRAIRSSPVYHNSVIIALVKKSYFMLDEKDHIVA
LNLLETGFSRALIECSHEGILINELVGIYTSSLLPRTQLAAAHALYLALDRCRDMVHVTN
DKNIVQFLNKVSEKLLGYKTEEMMGRNLSEIVFYENSALMEQQLAKGREFEGNMNCKRKN
NQMITINCRIIPFCITLKKPSHYIYVYDTTYLSENSAPISPASSPLHPPLKTSILSNARK
SSDVRSGVSEGRRRSSLQKLHTLQLEAPITKVITLLSNAVTDTTNPETAAQIDKAIDILK
TTELYVPHLKEDRAMYSDPVATDLVGALLASPRTAWESRRSSSDSARLSTIKAIAYPANS
RVQVKNFRGPQELMDILDNSLDWNFEIFKLEVLTEKRPLVFLGLTIMNLYQVPATLHCDE
KTLQNWLAIIEHSYNAENSYHNSTHAADVMQATARFMQSKRLKEILEPLDEVAALIAAAA
HDIDHPGRSSQFLCNANSRLAILYNDLSVLESHHAALTFKLSLSDDSVNIFKNLDRDAYK
LLRQNVIDMILATEMTKHFEHLAKFMNVCSARIGDGQETYSDSLDMSVVLQPDNVILVKR
MMIKCADVSNPTRPLKCCVEWARRIAEEYFNQTDEEKKLKMPVVMPMFDRMTCSIPKSQI
GFVDYIINDMIEAWDVFIDMPEIVGYMRHNYEKWKEYNMSIVPLVFRNWWDDFDRPVSRL
LDQHFGTGLHRDDLISSLTGLGIDRPPLRSIFGNRPYYRPWGNVTRQNSSGTSTIQLDND
TFQVILDVQQFSPDEISVKTVDNHVVVEAKHEEKQDEHGYISRHFVRRYVLPPSHDLVNI
TSTLSSDGVLTITAPKKNMTPAGTERVVNIVQTGVPAAKPVPVETTAATTTTTTTTTTTD
>E9CK28|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia symbiotica str. Tucson|TrEMBL
MESLFKLPVASGNTARILQITDTHLFADKHETLLGINTYRSYHAVLDAIQAQRRELDLIA
ATGDLAQDHSLAAYQHFAEGIFQLPAPCVWLPGNHDYQPAMVDALTTAGIAPSKQVLLGD
SWQVILLDSQVYGVPHGELSEYQLEWMARCLQTHPERYTLLLLHHHPMPCGCTWLDQHSL
RNPHMLATTLLRYPKVTTLVCGHIHQDLDLEWQGRCLLTTPSTCVQFKPHSTHFTIDDVS
PGWRYLDLLPDGRVETQVYRLENNDFRPDMDSDGY
>A0A179R9L7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MSPPDQSRPVHVVQLTDAHLFADPAGSMLGLKTRDSLRHVVAQVRREQPLVDLLLCTGDL
SQDASVASYEAFRELTAPFAVPTRWLPGNHDEAQVMAQVAPELVQAVTDIGAWRVVMLNT
AVQGATHGFLQDDQLAVLEAALKEAGERHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDI
VEGYPQVRALLWGHVHQEWDEVREGRRLLATPSTCIQFAARSEDFQVSEEHPGYRWLRLH
ADGRLETGVERALDFEVQLDFDSPGY
>A0A7Y1HJD3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas lundensis|TrEMBL
MPSVSTLTTEDPVLLVQLSDSHLFADANGSLLGLNTARSLQQVIDLVSAEQPSVDVLLAT
GDLAQDGSVAAYQYFRQATAALAPVARWIPGNHDDVQQMREAAIQSRLMEPRVDVGNWRI
TLLHSNVLNKSHGYLEDDQLQRLAQSLSEAPERHHLVCLHHHPVPVGCQWIEPIGLLNAD
AFWAVVDRFPQAKAVLWGHVHQPFDQQRKAVRLLATPSTCFQFAPHSEDFKVSTEAPGYR
WLQLNPDGTLDTGTSRVAHFDFDPDYSQDKY
>A0A3B0LYP7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arsenophonus endosymbiont of Trialeurodes vaporariorum|TrEMBL
MDSLFKLTTKQKSLVRILQITDTHLFANVDDTLLGVNTFGSFHAVIDAILARNENVDLVV
ATGDLVQDQSASAYQHFAEGIKRLSAPCVWLQGNHDYQPAMVATLAKAGILPSKQVLIND
NWQILMLDSQIQGAVHGKLSKQQLLWMKRCFDAYRERSHLLMLHHHPLPSGCTWLDQHSL
RNSHILADYLIQYQQVKAILCGHIHQEIDEYWQGVRMMATPSTCIQFKPHCTNFTLDTMA
PGWRYLDLSINDNGENVLDTQVFRLDSDKFCPDFDSGGY
>T1PKA6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Musca domestica|TrEMBL
MRNCFTKITNVFRKQARHKSSEEGSLQQEDDDVYTRKKTTNTEPTVANIETAKKSTLSGC
LSLKTNDKHSGWDRRDGVGDNSEVAHTLNLSTQSIMDGDYEKHLQLRLSQRSSQSTMNEA
KNDYNRRDALHANDGVYQQKQLRLLGRNVDEAEKGQLLYMEATPSPVSFAIDASPTNGSH
RSFVADNKTNAMPTNYDKCNSNVAKTPEEMEYEAKVAAEFEDVMTPLPTTAKHIQFAFGR
NLRPEIAEVIRSLDANALRINNLTVEDKFELLRRFDCAQQARRHGRGNNFVRSMPPPGHS
IQIDLGLVGHEPDDPEDNPSDSSTEGVVLRRKHHQTPKEKSTSCLYERRLPKSPKLKLIL
ESKWKETSNGSKTGIAFKEVNDNDIERNAYDVKYPTVLPPNPQLKALLVFYKSDNICEVV
QQACNRQQLEISLVKTKETAFENLCSATECFHVIIIDARSPKHLDAEHIARSIRHMSGHH
FTTIIAVVKKSMFERDDVINALLDAGVNRCMAESTSLSMCAMELKQILHSIVRPHNVIST
QQALYTALHRLKEVLIITDDLLRIQYANRSAERLLNMRLDEVISKPLADIFISDVSTINS
SVQGKGIREFDGILTVKRKNQEGIPMHVRVVPVACIGRTPTHFVFNFDVPGGQMDFIATL
PQPKEAPRGSLHSIRRGSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQENC
SAEEARLIDKVMEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPNVYSSRRSSNDSIV
RTNCSNRQSTIMPAKMKATPLIMEILEESLNWEFNIFKLEEITENHPLLYLGMEIFRRFD
VFATLNVDENVCKNWLAIIERNYHADNSYHNSTHAADVMQATGVFISQLAAKDLVMDRLE
EASALIAAAAHDVDHPGRSSAFLCNSNSPLAILYNDLTVLESHHASTTFRLTLGDDNANI
FKNLDTDTYKVARTTIIDMILATEMTRHFEHLAKFVSVFGTEMEPRDIVQSEEESSVLMR
RMLIKVADVSNPARPMICCIEWSRRIAEEYFTQTDEEKAKNLPIVMPMFDRGTCSIPKSQ
IGFIEYIIQDMMHAWDSFIDMPELITYMQINYSQWKKFEEQGIHTLAEVKAKQMSLMNKK
SALK
>A0A2T3KT89|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium leiognathi subsp. mandapamensis|TrEMBL
MQTYLLPQTNPESVVLLQITDTHLFANESGSLLGVATQKSFHAVLDAVDTVAREFDAIVA
TGDISQDHTPESYQEFAGGIARWSQPCFWLPGNHDYQPTMASVLPSEQIKPCEQVLVGEH
WQMILLDSQVAGVPHGQLSQAQLALLDSALSQYPERHALVLLHHHPLPAGSAWLDQHQLH
NNDALWEVVEKHPQVKAILCGHIHQELDRMYRGVRVLATPSTCIQFLPDSDDFALDQENP
GWRYLELTPKGDVITHVHRLEGDQFKPTFDAAGY
>A0A3S7DQR2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sp. ASNIH4|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRIASQVWRLPVGQFVPDPNATGY
>A0A667YUC0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Myripristis murdjan|TrEMBL
EPKVSEVLAVSGGERMLNRELTQLSETSRSGNQVSEFISSTFLEKQHDVEILSPPSKEKE
NKRPMSQISGVKKATHSPSLAPTCIPRFGVSTQHESLLAREIEDINRWGLDIFKIAEYSG
NRPLTVVMYSIFQERELLKSFKIPPDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHV
LLSTPALEAVFTDLEIMAVLFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHL
AVGFKLLQEENCDIFQNLSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTS
LGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDRERDKGMEI
SPMCDKHNASIEKSQVTPPREQKKKKKSSWCYFS
>E6XJK9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella putrefaciens (strain 200)|TrEMBL
MLKEAVSYSIAEGESVRIVQVTDPHLFADPEAQLLGVNTSKSFAAVLNTIRAVDYPAHIM
LATGDLSQDYSAESYQQFVRAVTPVGLPCHYLPGNHDDPRIMYLHMQGEQIFGQQRILAG
KWQILMLDSTVRGKPGGHMAQSQFELIEQAIAAHPECYTLLVMHHNPILVNCTWLDQHCM
DNGAEFLERVAMYPQVKGLLWGHVHQRIDTHYEGPHGALQLMATPSTCIQFKPLSPYFAL
DGLQPGYRLLELKADGSIGTNVYRVPGNHFFPDNDSSGY
>L4J069|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli KTE146|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A0H2QFK5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moellerella wisconsensis|TrEMBL
MDSLLRLTAKNEKAVRILQITDTHLFADTENTLLGVNTHDSYHAVLDAIQAQGLEIDLIV
ATGDLVQDQSIGAYHRFAAGIARIPAPCVWLPGNHDYQPAMFDSLKAAGISSAKQIVIGN
EWQVLMLDSQIQDVPHGELSDYQLEWMKACLDNNSERSTIIMLHHHPLPSGCTWLDQHSL
RNSHILADYLKGYHQVKAMLCGHIHQEMDEDWHGIRLLATPSTSVQFKPHCTNFMLDTAA
PGWRYLELLIDEQGRKQVTTEVYRLSSRDFCPNLDSDGY
>A0A7D3UYX4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas hydrophila|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRIASQVWRLPVGQFVPDPDATGY
>A0A5J6X4E9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas simiae|TrEMBL
METELLQAPDGCVRLLQITDTHLFANAEAQLLGVRTADSLAAVIERIQGNDHPFDLILAT
GDLSQDHSAESYQRFADMLAPLGKPIYWLPGNHDDGALMTQSLYEAGISEQKWLIGKHWQ
IILLDTQVRGKPHGLLADHQLAALDHVLRSHPDKHTLIALHHQGIPVGCAWLDQHNLKNA
DDLFAVLARHPQGKTLLFGHVHQEFDELYKGVRLIASPSTCIQFKPLCDEFTLDESGPGW
RYLTLHPDGRIESQVWRLPPNSFIPDPTARGY
>A0A2X5PG21|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Tatumella ptyseos|TrEMBL
MLQLTDTHLFQGRHESLLGVNTWAGFQAVLDAILEQQDHFDLIIATGDLAQDHSVQAYRN
FAEGISRLPAPCVWLPGNHDFQPAMYDTLASAGISQCRHVLLGDDWQMLLLDSQVYGVPH
GMLCDFQLEWLETTLSRSPERDTIILLHHHPVPSGCRWLDQHSLRNSHQLDAVLQGYPRV
RALICGHIHQEMDEDWQGRRVLSSPSTCVQFKPHCSGFTIDALPPGWRWLTLKPGGEIET
AVCRLNTTDFLPDLESEGY
>A0A195E195|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trachymyrmex cornetzi|TrEMBL
MKDQIPYHRTVKNVEVSPRARRRAKIYKLLESIYLDKEEPKGPQDLSNYLLTTNVPSIVK
ILLVFSKDDQQMDILANTARRLGWSVSVAKDAEKALELFQNRAHELVIIDHRAHHAAEGD
AICRAIRSSPVYHNSVIIALVKKSYFMLDEKDHIVALNLLETGFNRALMECSHEGILINE
LVGIYTSSLLPRTQLAAAHALYLALDRCRDMVHVTNDKNIVQFLNKVSEKLLGYKVEEMM
GRNLSEIVYYENFPLMEQQLSKGREFEGNMNCKRKNNQMITINCRIIPFCITLKKPSHYI
YVYDTTYLSENSVPISPISSPLNPPLKTNITNARKSSDVRSGSISEDKGRRRSSLQKLHT
LQLEAPITKVITLLSNAVTDTTNPETAAQIDKAIDILKTTELYVPHLKEDRAMCSDPVAT
DLVGALLASPRTAWESRRSSSDSARLSTIKAITSPTNSRVQVKNFRGPQEIMEILDKSLD
WDFEIFKLEVLTERRPLVFLGLTIMNLYQVPATLHCDERTLQNWLAIIEHNYNAENSYHN
STHAADVLQATARFMQSKRLKEILEPLDEVAALIAAAAHDIDHPGRSSQFLCNANSRLAI
LYNDLSVLESHHAALTFKLSLSDDSVNIFKNMERDAYKLLRQNVIDMILATEMTKHFEHL
AKFMNVCSARIGDGQETYSDSLDMTVVLQPDNVILVKRMMIKCADVSNPTRPLKCCVEWA
RRIAEEYFNQTDEEKKLKMPVVMPMFDRMTCSIPKSQIGFVDYIINDMIEAWDVFIDMPE
IVGYMRHNYEKWKEYNEQGISTLQDVEKLQQHPEMQILRLS
>A0A447UXG8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cedecea lapagei|TrEMBL
MESLLTLPVADGGRIRILQITDTHLFAGKNETLLGINTWKSYQAVLAAIRAEQRSCDLLV
ATGDLAQDHSVEAYQHFAEGISSFSAPCVWLPGNHDFQPAMFSALQEAGISPAKRVYLGE
RWQVLLLDSQVFGVPHGELSDYQLEWLERQLAAAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAAALDAVLKPWPQVKTLLCGHIHQELDLDWNGRRMLATPSTCVQFKPHCANFTLDTIE
PGWRWLDLFPDGSLTTEVCRLQSGKFSPDTASEGY
>A0A1N6I7K8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salinivibrio sp. ES.052|TrEMBL
MQPCQIDNAHGDCIRLLQITDTHLFADEQGSLLGINTLHSYHAVLDAISMASPTFDAIIA
TGDLSQDHSALSYRRFVEGIDRWEQPCFWLPGNHDFQPEMSAVLQSKKRMACSQVLLGSH
WQMVLLDSQVAGVPHGELSQTQLNLLDTHLGDYPERHALVLLHHHPLEAGSTWLDQHQLA
NRDAFWQIMKRHPQAKVVVCGHIHQALDIRHQGVRVMAAPSTCIQFMPDSHDFALDNQNP
GWRWLELYQNGKIETQVERVTGRYFRPDFDSSGY
>A0A2S3SND6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio vulnificus|TrEMBL
MQHTSSDTLSENSIKLLQITDTHLFASDEGSLLSVKTLQSFQAVVEQVMARHVEFDYILA
TGDISQDHSAASYQRFADGIAPLEKACFWLPGNHDYKPNMSSVLPSPQITTPEQVALNPH
WQLILLDSQVVGVPHGRLSDQQLSMLEHYLQASPEKNTLILLHHHPLLVGSAWLDQHTLK
DAEAFWQIVERFPMVKGIVCGHVHQDMNVMHKGIRVMATPSTCVQFKPQSDDFALDTVSP
GWRELTLHANGEITTQVQRLASGSFLPDFTSSGY
>A0A7K0BTJ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinomadura macrotermitis|TrEMBL
MIRVAAAGDLHLGHKAAGTYRERLGALPEQADVLLVAGDLTRHGTVAEGRVVAGELRDVG
VPVIAVLGNHDYHSDEQDGITEVLREAGITVLEGDGTVLECGGIRLGVAGGKGFGGGFAG
RCASDFGEPVMKEFVAHTKEFSGRLGAALLALDCDVRIALTHYSPTADTLAGEPPEIFPF
LGSYLMAEAIDAGGVALAVHGHAHMGTEKGATPGGVRVRNVALPVIRQAYAVYALEGAGL
TAPVQR
>A0A0T9L5E3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia kristensenii|TrEMBL
MESLFKLPMASGAKVRILQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHSFDLIV
ATGDLAQDHSVAAYQNFAEGISRLPAPCVWLPGNHDFQPAMVDALANADIAPSKHVLVGD
NWQILLLDSQVFGVPYGELSDYQLEWMERCLVAYPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGRLETEVRRLASDEFCPDMDSDGY
>A0A5B0ED44|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. ANT_H12B|TrEMBL
MPSVSTLTTADSALLVQLSDSHLFADTDGTLLGMNTRDSLQKVIELVRLQQPRIDLIVAS
GDLSQDGTLESYQQFRDLTRQLDAPARWIPGNHDEPQIMAEAAVQSALLEPVVDVGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCFHHHPVSIGCEWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDQDRNGVRLIASPSTCIQFEPGSEDFKVGDQAPGYR
WLRLLPDGQLETGVERITGFDFQIDYGSNGY
>G2GWD5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Regiella insecticola 5.15|TrEMBL
MKKGAYLENLFKLPMPANETEIRILQLTDIHLFADKKKTLLGINTADSYSAVLEAIATQK
QRFDLIITTGDLAQEPAITSYQYFARGMAELLPTPCVWLPGNHDDQRIMADMLFDEGITA
TKQVIIGDNWQILLLDSQVSEQPYGHLSDHQLLWMEQCLQMFPRHYTLIALHHPPLACGC
RWLDQNNLRNASMLAEIVLRYPRVTTLLCGHIHQEIDLDWCGKRLLATPSTCIQFKPDHA
TFTLDNVAPGWRCINLQPDGTVKTQVQRLANGLFYPDISANGY
>A0A7J0AT16|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MKIQYCSDLHMEFHENMRFMKSLPLEPVGDVLVIAGDVGYLVDSTVPHLRFWKWASENYR
QVLMIAGNHEFYNNGDIAAQGESWQKMFLPNVGYYHNRVVRIDNVDFILSTLWSRIPIVD
EFVIKNGMNDYSQILYNKRRLIPQNINDEFDKNFAFIQKAVKDSDAEKIVVVTHHLPTIS
ALEQRHFGDVLNAAYATELGNYIADSRISAWIYGHSHHSTDLMIDNTHLVSNPLGYVFCG
ENTNFNDSAVIEV
>A0A7J0ABK4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MKILHISDTHGCHHRLKNLPTADVLVHSGDFTMTGSEKEALDFLEWFCDLSYRHKIFICG
NHDECMYGADIDGLDANVHYLCNSGIEIDGVKFYGVPMFMGDCATSRQSCNYDNIPADTD
VLITHSPAYGILDLDDGISGEFINYGSEELLNKLSALNIRAHLFGHIHRQHRILNHDGAI
YSNGAIMNEDYTQLNIQNLIDI
>A0A6I2IT75|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacteriaceae bacterium RIT711|TrEMBL
MESLLNLPVAGGGQIRILQITDTHLFSGKNETLLGINTWMSYQAVIDAILAEQRHYDLIV
ATGDLAQDHSAQAYQHFVEGIAEIPAPCVWLPGNHDFQPAMFSSLLEAGISPAKQVFLGD
SWQILLLDSQVFGVPHGELSDYQLDWLERKLSGAPERHTLLLLHHHPVPAGCSWLDQHSL
RNAAELDNVLQKYPKVKTLVCGHIHQELDLDWNGRRMLATPSTCVQFKPHCSNFTLDTIE
PGWRWLELHPNGEVTTEVCRLKGAVFNPDTASEGY
>A0A7G9ZCD0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methanosarcinales archaeon ANME-1 ERB7|TrEMBL
MKTKNIGKGVGDKFSVKNVWRSLIFCLVIFGLIGVADAQIFTEAVGGPGLDFGRSVVQDS
DGNFVITGPWSYSGGTYSDLSLIKVNRSGGLISASVLKGPSGNDLSETGNAVIEPSSTIS
TGVTVSESEPNNDHTTADPVELGDDYTGEISANIDIDYVSFFAKAGTILQATTEFDNSYL
ELFDVDGTTLIAHGTNYGQAGVPSKITFTILTDGTYYLAVKKPWDSWPASYTLEIRTKDL
VVVGHSNSFSSGFNATIARFSSDGNTLRWAKILSPPGGATSFGLSVTEVSDGGFVMTGPI
WNHPNGQGMDLFIAKFSNDGNFLWGNVVGGSGDDCGSSVIEANNQDLVVAGWTTSFDAMD
LLLARFDANGALLWAKAYGGAGSESGWSVIEVNSDLFVTGATNSFGAGGDDLLLVKFDLN
GNHIWTKTLGGPNDDRGHSLVFTFCGGNYPPMAPCGIAITGATESFGQGGQDLLVTMFDL
HGNYQWARTLNAADPGTANDGGFSVIDACYEYNIAGWEVPMNCKLAFAGYTYSWGTGGED
ILFGTFDYYGYTACEEIVDAIVGPATLPSPGSLGSLTTDLDANPITPVIQDITPTVTPVC
TTDFWQYTDVGPIDQPVVFSVASITDIHLRYGNPPFDQLKTVVDRINEAINAGEDIRFVM
VLGDIGDEGYRCTSDPYIEVKEVLDSLLVPYIPLPGNHDVWYDDNDGATPPDRTQSWFEK
PQEEIFNQVFSPQYDYLDNVVLPGWTKAAPVPVSCQPQGCSASMDCYFQDFAFDYMRYHF
ISPDWNSRGEICTKDKTDLIRGFPDLQKWTGNGAWDWFKNHLENYYNMGDENVLIFAHKP
LSPRASKQGGWPFYNFLTFNSDQYADIVNLLSLYASSVDKWFVGDWHVCDGVSLCCEENI
TDDVNNNVGSHVLTNIETRSVSSYPIPPGENIRLVRVHDALKLDFDYSPSQPTVNTLITF
LDQSATTSGTITTWDWDFGDGTHSGIQNPTYRYTEPGIYKVTLTVETSTGLKGSFATAID
VGTTQLTSEYEDATAYNNARRLIYDNGVLHLIYRWSPADWEAGLTYANSTDNGQTWFEVT
RSTLTGGDYPGGPLMGLYPALGVDTSGKPYIVKERTGGLGIPVFDAARREKPLGWFSYDH
VIESGSFGHPSVVVDSEGTLHIAISYDDGTSRKIRYYKGHPGGLIRIDNILDYEVIPAAG
SGECQFASIALDNSEVPHVIRQQGLEIYHSYRQGLNDWSNPEQISSGNAQTPSLVADGSV
LHAVWQEGDKVVYKKYDGGWPTTPTNVSTLSAGTIESYPQVGSRDGLICVVWADIAGGNY
EIFYSWTVTGSWSSPVNLSNTPAKSQYPQAAICSVSPNELCVVWTEGNGPTYDIRSKCF
>A0A737NQ94|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. houtenae serovar 44:z4,z24:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A175VIF5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas enteropelogenes|TrEMBL
METELPQAQDGSVHLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQANVHPYDLILAT
GDLSQDHSPESYQRFATMMAPLSRPIYWLPGNHDDSPLMTEHLHAAGISEAKQLVGEHWQ
VILLDTQVRGKPHGMIGDHQLEALDNALRQYPDRHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLISSPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRVASEVWRLPVGQFVPDPNATGY
>A0A7Y6TTC1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea brenneri|TrEMBL
MDSLLTLPAANGSAIRILQITDTHLFAGKHESLLGVNTWSSYEAVLDAIIAQHRDYDLII
ATGDLAQDHSVEAYQHFAEGISRMPRPCVWLPGNHDFQPAMVDTLADAHINPHKQVLIGE
QWQIVLLDSQVFGVPHGMLSDYQLEWLENALARYPQRHTLVLLHHHPLASGCTWLDQHSL
RNSHQLDAVLQQFPLAKTLVCGHIHQELDVEWHGRRVLATPSTCVQFKPHCTSFAIDTVA
PGWRWFTLHPDGQLETEVNRLDTDIFRPDLDSEGY
>D3Z2G1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus musculus|TrEMBL
MRRSGTALSFLWTERVREPVDSGVAPVSPLGGGVILRRFSGTLLLPPLSSRLGSSGEAES
AAHVVFTIGTQGTQRNLGSAQSSFDLENGLPGGKGLLDAQSGPSLGRALQPPVHHVQRRE
SFLYRSDSDHEPSPKAVSRTSSAASDLHGEDMIVTPFAQVLASLRTVRNNVAALAHGP
>A0A7Y8FCC6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas yamanorum|TrEMBL
MPSVSALNPDASALLVQLSDSHLFAEADGGLLGMNTRDSLQRVIETVLAQQPQIDLVLAT
GDLSQDGTLASYQAFRDMSRQIEAPARWIPGNHDEPQVMQHAAINSALLEPVVDVGNWRV
TLLDSAVPGSVPGYLQDQQLQLLAQSLSEAPTRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERVEGFAFQVDYGSNGY
>A0A6J5K4X1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia phenoliruptrix|TrEMBL
MKIRVLSDLHLENDEPELIPHAQADLIVLAGDIHNHAAGPRWAAQTFDGAAPVVYVPGNH
EYYDGEFGALEAALHDAASQVENVHVLNNAALIDPQGRWRVLGTTLWTDFALFGADHAAL
AESIEAARRAMLDFRGLIQMNWPHGVKNCARDEARDFAPGDALALHRQARAWLENELAKP
FAGQTIVVTHHAPHRLSLAERYADDRVSAGFVNHLPELVRAPVALWIHGHTHTSFDYTVN
GTRVVCNPRGYFDRRSGQWENPLFAWDKVVEI
>A0A737BTM9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. indica serovar 45:a:e,n,x|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLVNFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A2D0KEV1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus ishibashii|TrEMBL
MESLLEVPVAEGATARILQITDMHLFANKEDSLLGVNTYRSYHAVLDMILQQNLNIDLIV
ATGDLVQDQTINAYQHFAEGIARLPAPCVWLPGNHDYQPAMVDSLAAAGISPSKQIFIGQ
HWQLIMLDSQVQGVPHGELTDYQLEWMKKCLDKHNDRHAIIMLHHHPIPSGCTWLDQHSL
RNAPALSEYLKGKTQVKAILCGHIHQEVDEMWNGIRVMATPSTCVQFKPHCTNFMLDTVA
PGWRYLELPVAGNTKEVELQTQVHRLKNNEFCPDLDSDGY
>A0A3Q9JH95|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microbacterium oxydans|TrEMBL
MSRRKPPAPDPTLSRRGFTRLLRPASLVAVAACIAAPALTAAPAFAAPNFTAPAVAASDR
SALAVSDSEAPGSTETGGTIIRLDGEAPTSGQVGRAIVLPPAAAVDVDGSASELVVTVKD
PSGVVTMVMPEESGGYRFTPTIPGEYVVAYSISDAAGGVSEETRTITVTGAPDAAVAAAP
SVAAAPAVEAGGPDVRFAAIGDIHVNWDELAEAYDFWAQENVQTALFVGDLTNSATPGEF
AGLKQTMDSKAGLGIPAIASLGNHDVSGISSYDLFTQATGGQKPNADYTVNGYHVITVSP
GSGTIDPDTGKPSGASGGNYAYAQSWLQQRLAAATAEDPNKPVMVLVHHPLQCTHYVSNE
WYGTGLSSGCGDGFQSVFDDFPQAVVWGGHIHTPQNIPTSIWQGQENRSGERSTQGFTTV
NAPPLAYYEFESGVVNSSPTSRGNDTTPDDAGNNRQTAIVEITGTTVTIKNYDLLADQWI
DQTWTWDVADSVDETKSYDERFPFNDTYRASQSAGPVWPEGAAVTVGDIASAKAMVSFPH
AVPAPNSVGDIVHKYRYSTVDVATGEEVNSFLQWSGFYNLPMPADRRHEVWNLLPGKEYE
VRVTPINAWGKEGPALTARFTSTEGSGGEGPFDPSSLTFDDLRAALPTADLLDVGFAGGT
ASDSSPAARPLTAGADARIENDPAVGSDVVIGAEGAATGIRTPKWTDAEYAALQDGFTLD
ATFRLDAIAGGYVDVFGGMQSGGIGLEAVGTSATTYELQFWYASPRPAVSLKYGQWYHVT
AWYDGQDARLYVDGVRKAESEGVSFSVKPSAADARYMVIGGDANTSGALDDATMDGRIAG
VEVYSAPLSDKDVYRVATRELTALDTMPPLVRVAPEPAGEATVGTAYTAPRAEAVDNSGR
VSTMLEVTDPSGAPVPVDDPASGLRALAAAAGDGYTFTPTATGTYTLKYIATDAAARQNQ
VTFTVTSTAGSDGGNPGGNPGGNPGGGNTGGGANQGGGSAGGQSDPLAATGGPAPTMLAF
AGLLLLAGGGVLLRRRMLRRPEGQE
>A0A6I4KSJ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas xionganensis|TrEMBL
MPSVQPQTIADASVLLVQLSDSHLFAEADGKLLGMDTRDSLQRVIEQVLREQPQIDLMLA
SGDLSQDGSSASYARFREMTAVIPGSARWFPGNHDEVPAMQAACAGSDLLDPVIDLGNWR
IVLLDSSIPGAVPGYLADSQLALLEQALSETPERHVLVCLHHHPVSIGCKWMEPIGLRNP
QALFAVLERFSHVRALLWGHIHQEFDRMQAGVRLLASPSTCVQFAPGSEEFQVDTTAPGY
RWLRLYADGRLDTGVSRVTGIKFEIDYSIKGY
>A0A8D0G403|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sphenodon punctatus|TrEMBL
MSFEIWFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQHEVEMPSPTQKEKDKKKRPM
SQISGVKKLMHSSSLTNSSIPKFGVKTEQEDILAKELEDVNKWGLHVFKIADLSGNRPLT
VVMYTIFQERDLLKTFKIPADILITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTP
ALEAVFTDLEILAAIFASAIHHVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLL
LDNYSDRIQVLQNMVHCADLSNPTKPLQIYRQWTDRIMEEFFRQGDRERERGMEISPMCD
KHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPASD
DQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVGEEVEEEESQTDPCVLEEDCSPDT
>A0A4R6DZ24|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Buttiauxella sp. JUb87|TrEMBL
MESLLNLPVAGGGQIRILQITDTHLFSGKNETLLGINTWMSYQAVIAAILAEQRQYDLIV
ATGDLAQDHSAQAYQHFVEGIAEIPAPCVWLPGNHDFQPAMFSSLLEAGISPAKQVFLGD
NWQILLLDSQVFGVPHGELSDYQLDWLERKLAAEPERHTLLLLHHHPVPAGCSWLDQHSL
RNAAELDNVLQKFPKVKTLVCGHIHQELDLDWNGRRMLATPSTCVQFKPHCSNFTLDTIE
PGWRWLELHPNGEVTTEVCRLKGAVFNPDTASEGY
>A0A8D0HBA3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sphenodon punctatus|TrEMBL
TFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNS
SLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNK
>A0A5E4LI79|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MPMDAKALVAVVSIFLVAGCIEATQCNGAGCSVLKPFAGSDCNASQGCTQVLAAGDFTYC
GLSGNTILVSRIPGAVPGRILGLGDYPHGTGLPSEYLDCFAPYWDAFKQRFYPVPGNHDY
MTPGAEGYFGYFGPAAGDRNKGYYSFDLGQWHFVALNTNCTDVNCDAGSAQEKWLRSDLS
ANSGKCTIAFMHHPAFSTGVHGDENSVSAIWHALYDEGVDVALTGHEHSYERFAPLDANG
KADYAKGVRLFIVGTGGATLRKLNGSVYPVEVKNDSSHGMLALRLYSNSYEWEFLPAEGY
TFTDRGAGTCH
>A0A508YP19|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Limosilactobacillus mucosae|TrEMBL
MMRFVTSDTHFLDQHLLGVDDFAPRPFADTEQMDEQIIEHWNAKVAENDIVYHLGDIAVY
FAKPAKRADEAIFEILNTLHGHLVLIKGNHDRRELFKYLAAHNYDLNGQPKFSFHDVGAL
IKYNHCQYYLTHYPMMLEIAPRIINLHGHIHHYAVPVKENVNVGIDSPELEYLKKRPAFG
EPLTLAEVETIARIKAEKLTRH
>A0A8C1DQB4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyprinus carpio|TrEMBL
MTRFYCTSLATNLGAHMSFWEMYSKRRENVQLSVQTLFLCKENLYFFFVLNYCFCTVVVF
LFVCFITPFSLFLCSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDS
DYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQQDRTSNKRSP
MCNQPPLSKASFTGEILIPFQKLDFKTLNCVFHSVVLFSLALHVIFHSFYVKC
>Q0I352|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus somnus (strain 129Pt)|TrEMBL
MISTYQYPTSEKVVRLIQITDPHLFKEKNGELLGINTYDSFNQVLSEVLQSKFDYELVLA
TGDLVQDSSEEGYQYFAESVKLLNKKVFWIPGNHDFQPKMFDVLSQYQEYIYPTKHVLVG
KNWQILMLDSQVSGVPHGYLGQYQLDWLSAKLRDYPKRHALVVLHHHIVSTNSAWLDQHN
LRNSLDLMQVLLPFRKVRGILYGHIHQAMDTKWQGYKIMATPSTCIQFKPDSNHFSLDTS
QPGWREIELYDDGRIETRVKRIQQTSFLPNMLSEGY
>A0A656IL42|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enteritidis (strain 2009K0958)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A2J4RCK3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella michiganensis|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFTAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
QWQVLLMDSQVFGVPHGELSDFQLEWLEQKLTEVPQRYTLLLLHHHPMPSGCSWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A670JTI3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Podarcis muralis|TrEMBL
MPFPPLQQLPGNLPNPQSLFTPGSKWRSSFVLFDVDNGTSSGRSPLDPMTSPGSGLILQA
NFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
AALTNLPDRAPSKRSPMCNQPSINKATITGKTT
>A0A2P7QXA7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Zobellella endophytica|TrEMBL
MNTATTSPDSTHLGSHREDGVAELLQITDTHLFADAGTELLGIATFDSCRAVVEAIREDA
EPKDAILATGDLSQDHSPESYRRFTGLMATLAPPVYWLPGNHDDAPVMQAELDAAGISNA
KHLLLAHWQILLLDTQVRGKAHGELAEAQLALLDEVIRRYPRHHLLVAVHHQAVPVGCAW
LDQHNLRNAEAFRQRLSRHQASRAVLFGHVHQGFDEVHDGVRYLASPSTCIQFKPLSDDF
ALDTTAPGWRALSLYPDGRLSTRVWRLPPDAFVPDFSATGY
>A0A223ZEN4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methanothermobacter sp. EMTCatA1|TrEMBL
MKRELQVSVFLTFITLAYYLLNSLALEFLGVEFISIPLTILLPASILFERARPNPISRAT
YIFSMLWLVFLIYLLMGWALVQFIWFFMDLPWLRILAVSLAALSVSYGVFRARKIEVKCL
EIPFPVERRVRFVQLSDIHLGTVRSAGFLKEVSGAVRRAEPAAVLITGDLLDGSRPVDSR
VLSSLETGAPIFFVSGNHDIYSGDFRSTVSDAGIRCIDQSVIDFEGIQIIGVGYSMERHS
LPAILDMLDFDGDRPALLLHHLPVDWGDARERGIDLQLSGHTHGGQFYPFNIIVGLMFPF
LRGLYSDSGRFLYVSEGTGTWGPPVRLGSSCEVTVIDLVPATADYNDGRI
>A0A212KSP1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chlamydiales bacterium SCGC AG-110-M15|TrEMBL
MPTPQDLLRLAQNECQGIDDEKVKNSLKKILKDLGKYDFKLKSFGVEGTNSSVKNRVAIK
DHQSALLCSIDKNFNVIRVGDHLLSTLLVDRQSVINKPLKALLTSESSKYAESLIFPEIC
ENELVQGKEIQLMKKDGSVIDVILTAIVEKDEAGAFSGAVISLDDVSELVETKQALSHAN
QRYDELYHSNSVILYSIGESRRILNISNPCLEALRYRSSEVVGRDIKDFLDEKSKKLFEE
CIYPNCSRALEVKGVELNFISGGGKAIPFSLSARIKKNDQGEVEKVIFNLDPLFNQPNSC
EVLEERHEKSELVRSSIQTPLKDSIQKLETLLMVLPEEHHKVLHGVIEHLSDDKLFRPKF
TDIEQFRKIDAQISKWLISEYSTISNVETHFTPLHNKGDELNDDLGVLNSLSFNAFEYVG
KQEKLIGYVVEMFKHFNLLEKFKIDEEAFKFFLHRVKTGYRNVPFHNFLHSFDITQMIFY
ILTKGGLASYLTDLDILALLVSVIGHDIGHTGLNGNYHEMTESPLALRYNDQSILESDHS
SRLFQILAQPGCDIFKNLSPEDRKEIRATIISNILSTDMQHHFEVLTLFSNRINAIESFD
PNQKEDRLLLMKISLKCADVSNAVRPFKTSSQWSKRVLDEYFLQGDLEKAAGLPVSAFMD
RDTTSIPKSQTAFIEFIVKPLYGTYSLAMPGMQECMENLEDNYQRWQKALADEESK
>A0A1B6C1K8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clastoptera arizonana|TrEMBL
MRFSWFHGEKICRSLRAVKKSNHVIFVAICKKNVVDKDEKELRSALKLGFNRVLVEPLSI
TQCVCELVQLAHGQLDLHSILAQNEAIYLALDKSRDLVLVTDSLHVIQYVNRTWCQVLGY
KSEDLIGRSLHSFHQLGNMDPVTRQLEKGFDWEGKISWRSKSGENITLQCRAMPYQAIGS
EPTHYVYVQDNPLENHIYPRGSIPSIRKGSYDLKSINSEGAQSARRQSLAKLHNLPLEAP
ITRVISLICAAQENSTGQVVQILDKVVDILRTTELYSSHLKADNLRCEDPVTSDLIGALI
TVSKLSHQGPVPVSTTRRSSNDSAAVKAQQAGLSGNKPIFSMSASPQLKELLDTSLQWDF
NIFKLEEITGKRPLVYLGMNLLMHFDVHKTLGCDEKTLYNWLTVIERNYHLSNTYHNSTH
AADVLQAMAGFLEKERIKRLVDELDEACCLIAAATHDIDHPGKSSAFLCNAGNELALLYN
DVSVLESHHAALTFKLTLRDDRVNIFKGLERDTYKVARQSIIDMILATEMTKHFEHLAKF
VSVFNKPSPTSEDGNCDNRFFDSSSSSDTEIASMVPTFSQHRVDVTSGVFQNHMVYM
>A0A740VHM3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar 6,7:c:1,5|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYGALQEAGISPAKHVLIGE
EWQILLLDSQVFGVPHGELSEFQLEWLERKLANAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSLLAHFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A446CIA6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter veterisilvae|TrEMBL
MARIHSLTRRDDAPAMLVQVTDSHLFGEAGTSMLGVDTDASLRAVLRQIEADGRHPDLLL
ATGDLSQDGEAAAYRRFAAILSEAPALDRACVRCLPGNHDLPAVMRQELAEWSVPVADVG
AWRVVTLDTTVPGSNAGHLPDAQLDMLEAALAEAPGRHTLVAMHHNPMQIDSHWHDTMMI
DNPQALFKLLARWPQVRVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNMA
PGYRWIKLYQDGSMATGVRRVQDALWHTALAAPDKARAA
>A0A7C3PLC2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oscillatoriales cyanobacterium SpSt-418|TrEMBL
MNGLAPLVVAQITDLHLFAESNRSLLGVHTSESWNAVLAQVAELQRRPDLILLTGDLSQD
GKAESYLHLKKSLAPLGIPTYWLPGNHDKLAAMEEVLEGGVISAEKSFAVDDWHFVLLNS
QVPGCVHGQLSEESLQWLDQELSTHPEKHAIVALHHPPFKVDSDWLDGSNLQNADELFEV
LAAHSQVKLVLFGHIHQEFSCWRQGIQYFGTPSTCIQFEPHSNEFALDQETPGFRLLYLY
PDETWWTTVERTEYAATQMDLAATGY
>G9KFQ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mustela putorius furo|TrEMBL
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKK
KQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSH
NRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVAQSTHV
LLSTPAL
>A0A3D9UQG5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus cabanillasii|TrEMBL
MESLLEIPVAKGATARILQITDMHLFANKGDSLLGVNTYRSYHAVLDAILEQNLDIDLVV
ATGDLVQDQTTGAYQHFVEGVARLPAPCVWLPGNHDYQPAMVDVLAAAGLPLSKQIFIGQ
HWQLIMLDSQVQGVPHGELTDYQLEWMTKCLDEHSDRYTVVMLHHHPVPSGCTWLDQHCL
RNAPALAEFLKDKPQVKTILCGHIHQELDDMWNGIRVMATPSTCVQFKPHCTNFMLDTMA
PGWRYLELSVTGEGEAKLQTQLHRLKSNEFCPDLDSDGY
>A0A6S7CHQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter anxifer|TrEMBL
MKFIHLTDTHLVADAGNLYGTNPKQRLQQAVAHILARQPDADAVAITGDLTHYGHAEAYA
HLRECLEPLTMPVFPILGNHDRRQHFQQYFPQVGRDPKGFVQYAVEFGDYLALFLDTNEA
GVHWGVFCEHRAAWLREQLAASAKPVLLFMHHPFFPIGIRSMDFISLRDTGPFLAAIAGF
EARIRQVFFGHIHRPICGVYRGIGYSTLRGTNHQVALDLHGDERHIVGVHEQPQYGVVLL
AADQVLIHAEDYLDCGERYSLHEMREGKQD
>A4N2S3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae R3021|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQAVLLDSQVYGVPHGQLSQHQLDLLKETLEKNPARYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLVPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTQVKRIQQAEFLPNMQEEGY
>A0A4P7CI46|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinobacillus indolicus|TrEMBL
MDDSYTFPLKSPIVRILQITDPHLFASDDGELLGVNTTQSFQAVLNAIEQDLFDYDFILA
TGDLVQDHNREAYHRFTKMVKPLAKPIFWVEGNHDLQPQMRNALSLYAQMQPEKHILAGD
FWQVILLDSHIEGVPGGALSTSQLDFLKAKLETYPERYSLIVLHHNILPTNSAWLDQHSL
ANADQLAEILKPYPKAKAILHGHIHQEVDKLWKGYRVLATPSTCIQFKPNCDNFTLDPVP
QGWREICLNLDGSIDTRVKRLDCNDFLPNFNALGY
>A0A2T3MTN5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium lipolyticum|TrEMBL
MQTYSLPQTNPDSVALLQITDTHLFADEAGSLLGVVTKDSFHAVLDAVDAAARPFDAIVA
TGDISQDHSRVSYQYFAGGIARWPQPCFWLPGNHDFQPSMQSVLPSAQIKSCEQVLAGDY
WQVILLDSQVPGVPHGELSEAQLTMLDQALAAYPDRHALVLLHHHPLDAGSTWLDQHQLH
NSDAFWQVIGKYPKVSTILCGHIHQELDRTYRGVRVLATPSTCIQFLPDSNDFALDKISP
GWRYLELTRDGQLNTAVSRLQGNCFTPEFDAVGY
>A0A6F9Z7M8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacteroidaceae bacterium|TrEMBL
MKKSILVFSFLWALMIGGISAQTLKFNANGKFKIVQFTDVHYIADDPRSAVAIERIGEVL
DAEKPDLVVFTGDVIYGKPAEKSMCAVLNLVSERKYPFAVTFGNHDDEQGLSREELLKII
QRIPGNLTASAEGVSGVTNFVLPVKSSDGMRDAEILYMFDSHSYSQIKGIGGYDYIDFDQ
IQWYRDNSRKYTASNGGMVIPSLAFFHIALPEFRQAVVGESVPFFGIRKEKVCAPLLNSG
LFASMKEMGDVQGVFVGHDHDNDYAVMWQGILLAYGRYTGGDTVYNNLSNGARVIELTEG
EKSFRTWIRLKGNHVEQEVEFPESFLRPRK
>A0A8E4IMJ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia fergusonii|TrEMBL
MESLLTLPLAGEATVRILQITDTHLFAQKHETLLGVNTWESYQAVLEAIHAQQHEYDLIV
ATGDLAQDQTSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
HWQILLLDSQVFGVPHGELSDFQLEWLEKKLADAPQRHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLANFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTPDTIA
PGWRTLELHADGTLTTQVHRLSDTRFQPDTASEGY
>D2TRM9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter rodentium (strain ICC168)|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIHADGQEYDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKCVMAGE
HWQILLLDSQVFGVPHGELSEFQLEWLENKLAAAPERYTLLLLHHHPMPAGCSWLDQHSL
RNAAELDSVLANYPRVTHLLCGHIHQDLDVDWNGRRLLATPSTCVQFKPHCANFTLDTIS
PGWRTLELFADGTLQTDICRLQGDAFRPDTDSEGY
>A0A1I4VWZ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Izhakiella capsodis|TrEMBL
MDSLLKLSMASGASVRILQLTDTHLFAGKHETLLGVNTWASYKAVLDAIDLQSTHYDLII
ATGDLAQDHSIEAYQHFVEGIQRLPAPCVWLPGNHDFQPAMHATLAAAKIEQAKQVLLGN
SWQLVLLDSQVSGVPYGELSDYQLDWLEKALARYPQRHTLVLLHHHPMPSGCTWLDQHSL
RNAPMLDDVLRHFPLAKTLVCGHIHQALDLDWNGRRVLATPSTCVQFKPHCTRFTIDKEP
PGWRWLDLYADGRVETVIERLTISAFTPDLDSEGY
>A0A0E3ZNW9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurella multocida subsp. multocida OH4807|TrEMBL
MFSTYTYDTVAEVCKFVQITDPHLFKDEKGELLGINTFQSFVQVVKEIKESGFDYDFVLA
TGDLVQDSSDEGYLHFCDQIKHLEKMVFWIPGNHDFQPKMFDILNQDQVHLNAKKHLLLG
KYWQIVMLDSQVFGVPHGKLSQYQIDWLVSKLKDYPERHALIVLHHHILPTNSAWLDQHN
LRNAYELAEALSSFNNVKGVMYGHIHQAVDSEWQGYKVMATPSTCIQFKPDNHSFTLDTL
QPGWREVTLYPEGKIDTCVKRIQHAQFFPNMHEEGY
>A0A3D0EI88|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp|TrEMBL
MDSLLTLPAVDGSDIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIEAQQHNYDLII
ATGDLAQDHTVEAYQHFVAGISRLPKPCVWLPGNHDFQPAMVDTLADAGIKSDKHVLLGD
HWQLVLLDSQVFGVPHGMLSEYQLEWLDSALRKYPERHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLQHFPRARNLVCGHIHQELDLDWHGRRVLASPSTCVQFKPHCTNFTIDTLA
PGWRWFTLQPDGTLETEVNRLQSDMFRPDLDSEGY
>A0A5F1HGI8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. E2562|TrEMBL
MESLLTLPLAGESRVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADSRFQPDTASEGY
>A0A8C9ET61|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pavo cristatus|TrEMBL
MKQQHSCAGTGQRGAVGRGRMGALELAVSPVKRLRTQYTFPCLFAEEAYQKLASETLEEL
DWCLDQLETLQTRHSVSEMASNKVGATLGLVPVSPPCPREGPLCRVGRGVRRCREPRRAP
SDALWQRGSHACTLYVIKTQTGVFGCCGDPFV
>A0A644WD16|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKFAHLSDTHLGYRQYGLIEREEDFYNVFNEIVDKIIDERVDFVIHSGDLFEMAKPSPNA
LLIFQEGLIKIKEAGIPFYSIAGNHDTIMRQNAIPPQVLFKKLGLTLISPKNPTINSSFL
RDNDIFIGGTPFISKSQNSFLKSQLNNLSKKSESFSKRILVSHQGIDKYMPFEYELEIGD
LPTNFNYYAMGHVHNRIVDDFGKGKLVYPGSTEIWRSNEVSDYKKNGKGFYIVDISENDA
ETNFEVESINIDLPREFINKTIEYGKLNSELESLETYISSLNNKPVLNITVENGSFNTGD
VYKKLNNILSKITLMFRPTFRNEELIKEERYIENNNSLEPRDLLIDSLKSFENEDISNLA
IDLLDFLSKDKFEDSVKISDSFYEEYFGQYETEFKKIMKHESKNKIKKTNKETKDSKNIN
EQDNFENINKDDNKKEEKGKGNKNNGINKEKDKNLKNKDDNKFKQTTINFN
>A0A644UH23|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MSNSTENSSDSTTIIAHISDLHISNNAFDDEIFLEVVNQINDLAPDMVIVTGDLTDHGYY
SEFLKAKEYLSMIQFPLFAVPGNHDSRNVGYEIFEELIGERSWVLTKDNDLTVVGMDSSG
PDIDRGHIGRPQQLWMENELDKSLENSNFSIVAMHHHVIPVPKTGRERNVLSDAGDILQS
LIDHDVNMVICGHKHVPHLWRMENTLFINAGSVSSIKLRGKDKNSYNTYHIRSDHIDVVL
NNINGEKLFLGKFNRI
>A0A644TU44|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MQYSMPKYAGRMPFLVLLFIFDWLILKNIGSLLNKFGSHIKRFFSVLWWFPLAVLLLFLL
GTAVFPLQSMGKFWRIYLPGIALMAYIAKVIMLIPLLPVFFLQIKAFVKDFFFRKKSETS
GKLFLFFRRMGLFIGGLAFAGLLIGSTIWVYKFKVHTVTLKIEELPDALEGLKIVQLSDL
HLGSWMSAAPLQRAIDKVNALNPDIVVFTGDMVNYSSAEVKGFESFLAQVKAPLGVYAIL
GNHDYGDYTSWKTPQEKDENLNVLIDFYKSIGWKLLQNTTEVISIDSARLLIAGVENWSA
TPRFKRYGDLAKTMEGVEYGDFNILLSHDPTHWDAEVLENYPRFDLTLSGHTHGMQMGIE
AFGMKWSPARYMYKHWAGLTIQGNRDGRDNYLYVNRGLGHIAYPGRVGILPEITLITLRK
AN
>A0A8J5CQU6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chionoecetes opilio|TrEMBL
MRGMQKDLRVLLVFVKDDGVCQAWRTAALRQNHSVTHTRTLETAVKAYNEETPDLVVVDV
RSAKSLSGVAVCGGLRNAEAGNLAVVVGVVKRRAPAWAQSLNELVQIEQCELATQTQMWA
SQAVLSALDGCREVVHITDTQHRIKYVNKACETLLGYTLEDVSGRSVWEIHSADLPTRPW
DNPRPSLEYRQPPQTPMEGAPLDTGEAVSAQLRRGREWEGVVTCRRRSGGALHLPSKVIP
VTPLSRRAQYYVYLMDTHVLDRLELSAAAAHDHPHFHPRGSIKSLRKGSHDIRSLSSDDY
RPQGIIRRQSLVKLHSLTLEAPITRVFSIITAAQENSPAYVAQALEKAVEILRSTELYAP
QLVSATASANAVEIASGSASARPVHSADPVQGPKPLLSVRRSSNDTAVKVAQQLPRPPMP
PLNEQASAAIRELLAEDMSWNFDIFKLEKISDKRPLVWLGMSLMCRFDLPDTLGCDESTL
QNWLTLIEANYHADNSYHNSTHAADVLQSTAYFLSRDRLKQLLDPLDVAACLVAAVIHDV
DHPGKNSAFLCNTNNELAVLYNDISVLESHHVAVSFKHTRSDDRVNIFKALDRDTYKHVR
KSIVDMVLATDMTRHFEHLSKFINMAGGTTTATTGGGDGVFEDDPALTSDLMSFGSPENL
VIMKRMLIKCADVSNPLRPLPLSIDWAYRIANEYFNQSVKPLSHERFLPSGFCRCGVRQK
PCLVAGTCGFCRRLSLSTSALVPQSSKYLVPRLSISEISNYVS
>A0A7Y8CEC4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas gingeri|TrEMBL
MSSVATQSTTTDSVLLVQLSDSHLFAEADGTLLGMNTRESLQRVIDCVLVEQPRVDLVLA
SGDLSQDGTLESYQCFRQMSGRIPAPARWFPGNHDELREMAEAASHSDLLEAVVDIGNWR
VTLLDSAVPGSVPGYLQDEQLQLLAQSLSEAPQRHHLVCFHHHPVSIDCAWMEPIGLRNP
EALFAVLDRFPQVRALLWGHIHQEFDQQRNDVRLLASPSTCVQFAPGSEDFKVDDKAPGY
RWLRLHPDGRLDTGVSRVRGFDFKVDYGGTGY
>A0A7V8IGP2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium fontis|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAIKARQDAFDLIV
ATGDLAQDHTLEAYRHFSRGIAQLPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHHLSAVLDRYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPEGRLETEVYRLSGSEFLPDMDSDGY
>V0VAG3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli 908519|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A7R9N7Y6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Methanoperedenaceae archaeon GB37|TrEMBL
MRLHKIILLLGILGVVVLQLQTGIASGSISVEDADAVRNFTLNTAPSDAINSTDVPQQET
FIDVFVNDADAARDFNLIGASDDALNSTDASEQETFIDVFVNDVDAMRDFDFSNSPPAGY
SVGQGAPDLATKNHFTDAYNRNGGADVLGSPTTEVHRAWGYLVQDFPGATGYAGGIIMYN
PYKNYAYYIHGAIWERYYDLGGPRATTDIEFELGPPVSDIEPYIHTHPPEVSSHGTQFRY
QNFEGGALEHNVDTGEVFEVHGAIFAKWRELGYADDELGLVTSDEREAAQSPIRTEGRVS
DFEGGHIHWHRTGGHAGKSYETHGAIDAVYCAEGGSGGDLGFPVSDEYVNPSGYPQSDFE
GGYITTTDGVNYYVYMNDDAEGPALEITSPEDGFHTDEYRIDISGTASDDSGILYGKVVI
ASSGFDNSDDRRTAKWDPETDKWETNIPLAHGDNVIRVFAVDNKHNPTEKTITVYCNPPD
FSFAHITDAHIDDDCETKWSWNNLKYEKYCESQEKFSSTLYEVNSKKPAFILDTGDCVEY
DDEELFKRYMETLDRYIDKDIKIYHTPGNHDRRNKFFETTDLSKYNAIVKPNNGPHTSLN
DGYGDYYFDEGGYRFIGLDSGHDWSVVDFLTPEGSGLEDDQYMRLLESDIKDHPKKIIFM
HHPVINEGDDGFGGIENRCPEKGGNDMCIGAFRCGLINYCIDHGVQLVLTGHTHKSYNVQ
ISNTRFIQTPSATKDTKWACPLVPDVVICKHGYRIIYIKSGKAYPQLYTTGAHSNVKGEL
ECPAHLHAYDSQGRHTGLNASGGVETGIPDSFYIGRYNYSDPNETETILLYNTTEEYRFE
IVANLTEEITGNESFNFTVEQQTDDTRTTIAHLRVPLTENTTATLPINLTTTAYTMEIDH
DGDGATDETEDPDFTVTNYAPTASINTPETGSIYNVSEPVEFNGTGRDPEDGILTNFSLV
WYSDINGVIGAGERFSTENLSAGAHRITLMVNDSTGLTATQHIALTITEPTTSSAPAWYL
HNDSTMCRTTTNPTGNLTIEGGSSNLWIADEPAQRDLTFPPGVWTGRITLETPLASGESF
SVAVGNCSGDIFTGSGSAVINGDGSRAFDFQITADSFEIVKDDYLAVNITDTTTGIEVKT
GGTQSYLVLLDNAPPYPVPELPGAFLIMVGLLILVGFVGRRW
>A0A2T3RUT4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia albertii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYLHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCRWLDQHSL
RNAGELDNVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A2R3J0Y5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas aeruginosa|TrEMBL
MSRHSNTPDTDASVLLVQLSDSHLFAEDGARLLGMDTAYSLEKVVERVAREQPSIDLILA
TGDVSQDGSLDSYARFRRLSAPLAAPLRWFAGNHDEREPMQQATAGSDLLEQVVDVGNWR
VVLLDSSIPGAVPGYLEEDQLELLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRQAPGY
RWLRLHADGRLETGISRVDDIAFEVDYDTAGY
>A0A380AJF3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia liquefaciens|TrEMBL
MESLFKPTVASGARVRILQITDTHLFAGENETLLGINTYRSYHAVLDAILAQQRDFDLVV
ATGDLAQDHSLAAYRHFAEGIARLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLVGD
HWQVLLLDSQVFGVPHGELSEYQLEWMERCLQAYPERYTLMLLHHHPLPSGCTWLDQHSL
RNPHMLGAVLLRYPKVNTLLCGHIHQELDLEWQGRRLLASPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRIETQVFRLENDDFRPDMDSDGY
>A0A2R4D5M2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Concord|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A3Z1TXM1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Haifa|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A1P8MGZ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio campbellii|TrEMBL
MQSSSDSIKLLQITDTHLFEADEGSLLSVRTADSFAAVVQEILNHQVQYEYILATGDISQ
DHSAESYQRFAEGIAPLKKDCFWLPGNHDYKPNMGSVLPSPQIQAAEHVMLGEHWQLVLL
DSQVVGVPHGRLSDQQLALLEEKLEENPQRHTLVLLHHHPLLVGSAWLDQHALKDADAFW
QVVDRFENVKGILCGHVHQDMNVLYNGIRVMATPSTCVQFKPDSDDFALDTESPGWRELE
LHSNGDITTEVNRLPDGQFQPDFNSNGY
>A0A3T6IYA3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella flexneri|TrEMBL
MESLLTLPLAGEARGRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A182GBB1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aedes albopictus|TrEMBL
MDSRSIYGCFRMRALFKKNNAAKSMESLYKPSVTTVDVLDVKKLDGVAVEARNGNLISTH
SSSLPDINAAPSDETEMLDEDNPESPVQLRRKYVPEEIIGSTDEEDLDSGYTTATPDVLE
LVKNLDRRALKLNEIILENDEHGKPTAYTRLNSNGSAFRPRSMERGLLAGGIRRHHRRRV
TSLHEIIEGRALDFDDRLISDLKFPNLLPPNPPIKILIAFCKNDPVFEALATACHRLNFE
PTFVKSAETAIEAFQNVATGGHHIIVVDARYPRIIEADVLGRSIRNSKGSQHTTMVAVVK
KNLFEKDDTAVISLLDVGFNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQALYTAL
HRSREAVIITDDSLRAQYANRASEKVLNMKLDEIVGRSLNDLVTADISNILSHTTRHKDY
EGFISTRRKSQETLHIHVRAVPVSCIGRSPTHLVLILEQTSGTTLSALASDALQALPHGK
EVARGSLHSIRRGSFDVRSIASDGLRRTSLAKLSQLPLEAPITKVLSLLAQVQENCSSDE
AKLLDRVMEFLKREGLYSPQMKEIRTEDPVATDLIGALLTQGPTNILSSRRSSNDSIIRG
GGRPSTGSIVFNKTRESSQLSELLNSALSWDFEIFKLEELTEKRPLVCLGLELFRRFDVY
NTFCCDEVTFKLWLIEIEKKYHSDNTYHNSTHAADVMQATACYLQQLSNRETKVMDRMDE
ATALIAAATHDIDHPGRSSAFLCNSDDRLALLYNDICVLESHHAATTFRLTMADDKINIF
KHLDRESYKLARSIIVDMILATEMTRHFEHLAKFVSVFGTDVDSKETTHDNDDNQILIRR
MLIKCADVSNPTRPLKFCVEWARRIAEEYFTQTDEEKHRNLPIVMPMFDRTTCSISKSQI
GFIEYIIQDMMDAWNSFIEMPEIVRYMEHNYSKWKLFEEQGINTLSDIKRKQLTLNSETT
GSSSIEEL
>A0A0A2YIW4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gallibacterium anatis|TrEMBL
MSDLFRDESAGVIKLLQVTDPHLFADEDGELLGINTFDSFRQVLSEIKKSGFESNYILAT
GDFVQDNSEAGYHRFVKEIVQLGKKIFWIPGNHDFQPKMEAVFDLYKAVIQPEKHLLLGE
SWQVILLDSQLYGVPHGMLSEEELKWLEQRLSLYPDRNTLIVLHHHLLPTNSAWLDQHNL
RNPYDFSEILAKYKNIKAIVYGHIHQEVNAVWQGIPVFATPSTCIQFKPDCAYFTLDNLQ
PGWREISLYPDGRLETKVHRIKDKVFLPKDNMNGY
>A0A5H5HR28|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Kedougou|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2N3IR01|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sobria|TrEMBL
METDLPQAQDGSLRLLQITDTHLFASQEGRLLAVRTAESLAAVLEQVQTNPHPYDVILAT
GDLSQDHSPESYQRFASMMAPLGRPIYWLPGNHDDSPLMTEYLHAAGISEAKQLVGDHWQ
VILLDTQVRGKPHGVLGDHQLAALDRALRQYPDRHALITLHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHHGVRLIASPSTCIQFKPLCDGFALDESGPGW
RYLTLYPDGRVASEVWRLPVGQFVPDPNATGY
>A0A379Z6K3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella algae|TrEMBL
MLKEAITYSIPEDKSVRLVQITDPHLFADPEGQLLGVNTANSLNAVINTIQAVKYPADML
LASGDISQDYSGESYRNFVEAIKPLNLPCHYLPGNHDDPRIMYLHMQGERVYGHRRVLAG
NWQIILLDSTVRGKPGGHMAESEIEIIRSAIAAEPDKHVLLVMHHNPVLVDCTWLDQHCM
DNGAHFLKEMGRYPQVKGMLWGHVHQQLDTEYQGETHKLSLMATPSTCIQFKPLSSYFAL
DALQPGYRLLELKPDGSMLTNVYRIPGERFAPDAEASGY
>A0A7D7DHE7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADSRFQPDTASEGY
>A0A034VBY3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bactrocera dorsalis|TrEMBL
SGGTGSAINGDDLLGHGNMCNQALLNPAQTKNEADYDKMCSGKKDSIVTVAALGNFTHTV
VRRATGSTGTSGTTSSGGASKPEKRKSSIALTPEDESIERSLMDVKFPTVLPPNPQLKAL
LVFHKSDNICEVVTEACHRQQLDVTVARTKEGALDTLTNTNEEFYHLIIIDARSTKHLDA
EYIARSIRHTNGHHFTTIIAVVKKSFFEKDDVLIALLDAGVNRCVPETTNLSMCNIELKQ
ILHSIVRPHNVMSTQQALYTALHRLKEVILITDNHLRIQYANRAAERLLNMRLDEIISKP
LADIFISDVSTIMIHGRKNKEFDEILTVRRKGQEDVAMHVRVIPVACIGRTPTHYVFNLD
VPGSHGDFVATLPQAREAPRGSQHSIRRGSVDVRSVASDGLRRTSLAKLTSLPLEAPITK
IINLLSQVQENCSPDEARLIDKVMEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSL
YSSRRSSNDSIIRVGGRQSTCMPAKMKATPHIMELLEESLSWEFDIFKLEEITEKRPLLY
LGMEMFRRFNVFATLNIDENVCKSWLAVIEANYHANNSYHNSTHAADVMQATGCFLTQLA
AKDMGMDHTDEAIALIAAAAHDVDHPGRSSAFLCNSRNTLALLYNDLCVLESHHASITFR
LTLSDDKVNIFKNLDTESYKSVRSVVIDMILATEMTRHFEHLAKFVSIFGSDEEPKDIVQ
SEEESSILIRRMMIKVADVSNPSRQPSYCIEWARRIAEEYFTQTDEEKAKTLPIVMPMFD
RNTCSIPKSQIGFIEYIIQDMMHAWDSFIDMPQLVTYMQINYSQWKKFEEQGVHTLADVK
SKQHSLSVKKSAK
>A0A0F3V3W4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYRHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7X3SYC3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia symbiotica|TrEMBL
MESLFKLPVASGNTARILQITDTHLFADKHETLLGINTYRSYHAVLDAIQAQRRELDLIV
ATGDLAQDHSLAAYQHFAEGIFQLPAPCVWLPGNHDYQPAMVDALTTAGIAPSKQVLLGD
SWQVILLDSQVYGVPHGELSEYQLEWMARCLQTHPERYTLLLLHHHPMPCGCTWLDQHSL
RNPHMLATTLLRYPKVTTLVCGHIHQDLDLEWQGRCLLTTPSTCVQFKPHSTHFTIDDVS
PGWRYLDLLPDGRVETQVYRLENNDFRPDMDSDGY
>A0A1H3L5U5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas salomonii|TrEMBL
MPSVSTVNPDAPALLVQLSDSHLFAEADGSLLGMNTHDSLQRVIGLVREQQPQIDLVLAT
GDLSQDGSLESYQQFRDLTGQIDAPARWIPGNHDEPQVMAHAAVHSDLLEPVVDIGHWRV
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPSRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVKAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERVKGFEFTVDYGSNGY
>A0A0H2WSQ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella paratyphi A (strain ATCC 9150 / SARB42)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPCVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A2N7JBC7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio kanaloae|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLSEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVSTQVRRLPHGQFLPDFDAAGY
>A0A380T9P7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|metagenome|TrEMBL
MLIAQISDLHLRAGGALTFERFDTADALGRAIDHINNLDPLPDVTLATGDLTDDGRPEEY
QALRAALDRLRMPAYVIPGNHDDRDNLRQAFADRGYLPADGEFLHYTVETWPLRLIGLDT
VIPGEIGGGLCSERLAWLVNRLAEQPDRPTLIFMHHPPFPTGIRYMDAPPLEGAAELEAL
IRRHAQVRQIVCGHIHRTIAVNWAGTVAAVGPSPVFQMNLALAPCGRFKPVAEVCAIALY
LWENGIGPIAHTSIVREQPARAVKAAVPA
>A0A6I8TU79|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aedes aegypti|TrEMBL
MDYNRGTSSSSGRYGHRQSSLALTPEEEPLDSYPRLISDLKFPNLLPPNPPIKILIAFCK
NDPVFEALVTASHRLNFEPTFVKSAETAIEAFQNAATGGHHIIVVDARYPRIIEADVLGR
SIRNSKGSQHTTMVAVVKKNLFEKDDTAVISLLDVGFNRCIIESPHVSICSSELRQIQHS
LVRPQNVISTQQALYTALHRSREAVIITDDSLRAQYANRASEKVLNMKLDEIVGRSLNDL
VTADISNILSHTTRHKDYEGFISTRRKSQETLHIHVRAVPVSCIGRNPTHLVLILEQTSG
TTLSALASDALQALPHGKEVARGSLHSIRRGSFDVRSTASDGLRRTSLAKLSQLPLEAPI
TKVLSLLAQVQENCSADESKLLDRVMEFLKREGLYSPQMKEIRTEDPVATDLIGALLTQG
PTNILSSRRSSNDSIIRGGGRPSTGSIVFNKTRESSQLSELLNSALSWDFEIFKLEELTE
KRPLVCLGLELFRRFDVYNTFCCDEVTFKLWLIEIEKKYHSDNTYHNSTHAADVMQATAC
YLQQLSNRETKVMDRMDEATALIAAATHDIDHPGRSSAFLCNSDDRLALLYNDICVLESH
HAATTFRLTMADDKINIFKHLDRESYKLARSIIVDMILATEMTRHFEHLAKFVSVFGTDV
DSKETTHDNDDNQILIRRMLIKCADVSNPTRPLKFCVEWARRIAEEYFTQTDEEKHRNLP
IVMPMFDRTTCSISKSQIGFIEYIIHDMMDAWNSFIEMPEIVRYMEHNYSKWKLFEEQGI
NTLSDIKRKQLTLNSETTGSSSIEEL
>A0A8B7LX44|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila elegans|TrEMBL
MIISSQPNLVGSVTTTTTTTATTATTTSAHMSEESVPSTCNCGGVGVSMAVGVAVGVGGT
LGARQNPPAVEATTTTAPKTPTSMASSRDSLTRPASESELNVGTGTSGTSSSGGGNSRPG
HRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLVFHKSDSICEAITAACQ
RHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSTKNLDAEHIARTIRHTHGHHLT
TIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMSTQQ
ALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSDLSTISEQC
KNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQPK
EAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQENCSADE
ARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGS
STRTATIVPAKMKSNPIIMELLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFAT
LNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDMLVMDRMEEAT
ALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLGDDKINIFKN
LDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPREHNSQTDEETSILMRRML
IKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRATCSIPKSQIGF
IEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLAEIMAKQPPVGKMANSK
>A0A3N2DIP1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Raoultella terrigena|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLEAIHASQRQCDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAAEPERYTLLLLHHHPLASGCSWLDQHSL
RNAAALDRALAAFPRVRHLLCGHIHQELDLNWGGRRMMATPSTCVQFKPHCDNFTLDTVS
PGWRWLDLHPDGTLTTEVCRLSGVKFHPDIASEGY
>A0A8B7LUC2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila elegans|TrEMBL
MGCSPSTLPAPSATAGQTDGPGSLPLDASEKDGSRLFCIKLRRSRLRRCSCGGVTLQPPS
DGNGSSTGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHSVVRRATGST
GTSGTSSSGGGNSRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLV
FHKSDSICEAITAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSTKNLDA
EHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQ
ILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQ
LEDIFVSDLSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFD
VPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITK
IINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSV
YSSRRSSNDSIIRTGSSTRTATIVPAKMKSNPIIMELLDESLSWDFDIFKLEEITDYHPL
LYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQ
LTNKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAI
TFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPREH
NSQTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMP
MFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLA
EIMAKQPPVGKMANSK
>A0A1H0N4Z1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas reinekei|TrEMBL
MPSVSTLSSVEPALLVQISDSHLFAEADGTLLGMNTRDSLQKVIELVQAQQPQIDLILAT
GDLSQDGTLESYQQFRDLTRQFDAPARWIPGNHDEPQIMAEAAVQSALLEPVVDIGNWRV
TLLDSAVPGSVPGFLQDDQLQLLVRALSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQVRAVLWGHVHQEIDQLRNNVRLIASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGQLETGVERVTGFDFQVDYGSNGY
>A0A5I9D2E9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar London|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5W0THU9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Worthington|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>Q80VK8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus musculus|TrEMBL
MTAKNSPKEFTASESEVCIKTFKEQMRLELELPKLPGNRPTSPKISPRSSPRNSPCFFRK
LLVNKSIRQRRRFTVAHTCFDVENGPSPGRSPLDPQAGSSSGLVLHAAFPGHSQRRESFL
YRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGAPNK
RSPAASQAPVSRVSLQVCDHRRLTKCRESKRC
>A0A8B9LDX5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Astyanax mexicanus|TrEMBL
MRQESFDVDNGTSSGRSPLDPMTSPSSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMS
RNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQQDRTSNK
>A0A1I5G7M4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. OV426|TrEMBL
MDSLLTLPAANGSEIRILQITDTHLFAGKHESLLGVNTWSSYEAVLNAIIAQHRDYDLII
ATGDLAQDHSIEAYQHFAEGISRLPRPCVWLPGNHDFQPAMVDTLAASHINAHKQVLVGE
QWQVVLLDSQVYGVPHGMLSDYQLEWLDNALARFPQRHTLVMLHHHPLASGCTWLDQHSL
RNSHQLDAVLQRYPLARTLVCGHIHQELDMEWHGRRVLATPSTCVQFKPHCTSFAIDTVA
PGWRWFTLHPDGGLETEVNRLDTDAFRPDLDSEGY
>A0A8K2A1U6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Petrachloros mirabilis ULC683|TrEMBL
MMLSHTLPLQLVQLSDLHLFAQAESDLLGLRTLDSFEAILSDLGQQHPRPDLLLLTGDLS
QDETPAAYARIGNLLRPLNTPTYWLPGNHDHLPTMQQALSTPPLYPDKSIHCGAWRLLLL
NSSVPGQVHGHLSATSLAWLEQELQVAAPHPTLIALHHPPFLVNSTWLDKSGLQNSEALF
AILDRYNHIKLVLFGHIHQEFHRQRQGVHYLSTPSTCIQFAPQSSGFALDEINPGYRCLT
LNPDGSFATQVRRIQMQQQLNLAAQGY
>A0A8E6KK78|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Paratyphi B str. CFSAN000541|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A6W0NUG5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Rubislaw str. ATCC 10717|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A7Y1Q1H9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas lactis|TrEMBL
MPSVSAVNPDAVLLVQLSDSHLFADADATMLGMNTRESLQRVVELVRAQQPAIDLILATG
DLSQDGTLASYQQFRDLTASLGAPARWIPGNHDEPQVMAQAAMHSDLLEPVVDIGNWRIT
LLDSAVPGSVPGYLQDAQLQLLAQALSEAPGRHHLVCFHHHPVPIGCAWMEPIGLRNPEA
LFAVLERFPQTKALLWGHVHQEIDSERDGVRLLASPSTCIQFAPGSEDFQVSEQAPGYRW
LRLHGDGRLETGVERVKGFAFTVDYGSNGY
>A0A3B5L7K0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xiphophorus couchianus|TrEMBL
MKSHPYVYSGYPSLTVCRVGDPGPASRPLKRALTDPLPSCLAPAEEAYQKLATETLEELD
WCLDQLETLQTRHSVSEMASNKVRITESSGTSCTVDFIDCSMRGGYQCSIT
>B4KS04|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila mojavensis|TrEMBL
MCCSPSTLPNSSSAAGPGAGNGGNAPLPPLDANEKDGSLLFCIKLRRSRMRRCSCGAVTL
QNQNGDGSTGSATCGDNMMCNQGLLNPLQTKNESDYEKLSTGKKDSIVTVAALGNFTHSV
VRRATGTGSTGTSGTSSSGGGRPGHRKSSLALALTPEDDSMDVYQRNLMDLKYPTVLPPN
PQLKALLVFHKSDSICEVVTLACQRHQLDVTLVKSKEEALETLHKSYATAQCYHLIIIDA
RSTKGLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDALIALLDAGVNRCIAETTNLT
LCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLNMR
LDEIISKPLGDIFVSDLSTISEQGKSIKEFDGILMVRRKNQESIPMHVRVVPVACIGSAP
THLIFNFDIPGGGMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSL
PLEAPITKENCSADEARLIDKVLDFLKREGLYSPQMKELRTDDPIATDLIGALLTGPSVY
SSRRSSNDSIIRTGNSTRAATIVPAKMKANPIIMELLEESLKWDFDIFKLEEITDYHPLL
YLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADVMQATGAFITQL
ASKDMVMDRMDEATALIAAAAHDVDHPGRSSAFLCNSNNPLAILYNDLTVLESHHAAITF
KLTLGDDKFNIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGSEVEPRELV
QSEEETSILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYFMQTDEEKQRHLPIVMPMF
DRATCSIPKSQIGFIEYIIQDMMHAWDGFIDMPELITCMQINYSQWKKYDEQGINTLADI
MAKQPPVGNKSSSSKXHTAFRRLFSGLLKPLPAQAPATSTIGENEMEDML
>A0A558F7M7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. H3(2019)|TrEMBL
MPSVSTLTANDAVLLVQLSDSHLFAEADKTLLGMNTRDSLQKVIELVLAQQPQIDLMIAS
GDVSQDGTLESYQQFREMTRQIDAPARWIPGNHDEPQIMARAAVQSQLLEPIVDIGNWRI
TLLDSAVPGSVPGYLQDDQLQLLVRALSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPD
ALFAVLDRFPQVRAVLWGHVHQEIDQLRNDVRLIASPSTCIQFEPGSVDFKVDTLAPGYR
WLRLLPDGRLETGVERVTGFDFQIDYGSNGY
>A0A106C2B4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella frigidimarina|TrEMBL
MLKDAVHYSVAENEPVRLVQVTDPHLFADPEGQLLGVNTAQSLQAVLNTFIATQYPANIL
LATGDISQDYSPESYQHFVQKIEMLDLPCHYLPGNHDDPRLMSLRMQGEKVFGQQRIIIG
NWLILMLDSTVRGKPGGYMGEQQFALIEAAIKATPDKHVLLVMHHNPILMQCAWLDQHCM
MNGEDFLQRTSRYPQVKGVLWGHVHQQVDNIHRGPHGPIPLMATPSTCIQFKPLSSYFAL
DHRQPGYRLLELAGDGSIRTNVYRVPGNRFAPDNEASGY
>A0A2H5VTB3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR09|TrEMBL
MFLLTVLTVWSFMHLYTFWRLAKLPWLATVPRWAWWAAGLLLWFSYPFARYLDRNGMSSE
FARLLELSGAVWLGTLFLLVTALLASELLTAFGLWKAAVVPIRTGSLALAALLSVVGVVQ
GNRTPQVESLEVQLPQLPRELDGLRVVQLSDLHLGTILREGWLSARLAQVQALKPDLVVV
TGDLIDGNARHVERLLPLLKELKAPLGVYAVTGNHEFYAGLEASVQLFRDAGFTVLRDQN
VEVRPGLVMAGVDDLTARRQYGINHRAVEKALAGRPPGACVFLSHTPWQVEEAARLGAAL
MLSGHTHDGQIWPFSYLVRLSYPYVGGTYRVNGLTLHVSRGTGTWGPRLRLWKPGEITLI
TLRSPSN
>A0A2R8BZW3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Palleronia abyssalis|TrEMBL
MTDQRDRTETDIEQGRVLVLADLHLDIWVRSGLDPLALIPAETWSSLDALIIAGDLSNNP
LGSWPVDLRKIGAHMPLDRVHLFPGNHDYFSHALDDEAIMGRAAVRVGANFAQKAQIVVG
RTRFLCCTLWTDFELLGDPVAAKAAAYRGMTDYRSIFMTMGDFRVLRPDHTLAVHRDHRA
WLESSLAEAFDGETIVVTHHAPVPDGVRQPVDELGPAFGSDLRELIEAHQPRAWYFGHTH
WPFRGRVGRTEVINFSVGYPSEVPVEGAAAFMTRGLVTLGRNGAPAVAAPAAAGDGGASE
>A0A803XRS6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Meleagris gallopavo|TrEMBL
MPYVSQCNVGEVGTATAHSWLHSPVTTPVHGDDLIVTPFAQVLASLRTVRNNFAALTNLQ
DRAPSKRSPMCNQPSINKATITGSYISMA
>A0A446C5H2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter agilis|TrEMBL
MTRILHLSDTHFGTERKPVVEAALDLARALAPELVVLSGDITQRARRGQFAAARKFIERL
SLPVLAVPGNHDIPLFNVFARALNPYGNYKRALGAVLEPVFENDGLLAIGVNTTTPRRRK
DGEISAGQIARVAQRLRQARPGQLRVVVAHHPVRAKVESDLSNLLIGREPALAAWTQAGV
DLVLGGHIHLPYVLPLDPSAPAGGWIVQAGTACSRRVRGNIPNSVNVITCGGEGGCHVER
WDYAAGAHAFAPVDKTLVAR
>A0A2H5YWI9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR27|TrEMBL
MTVPSSRTTRILAGCLTATGLALIGAATLEPYRLRTRVVQVTLPRGCDALTGTRIAFLTD
FHIGGPGPSARNTLEAIERLRAWRPHLVLLGGDYFDQGRFSPTAVFDGLCDIQPVFAVLG
NHDYRQGEHNARRIAAFLAERGVRVLQNECVVIDLPNGSQLELVGLDDPYTGLHDSSLLA
RPLTPHPRVLLAHSPSVLEAVSVGSADIGLFGHTHWGQIRLNWSRWLNPLDAAWYLDRIR
KKPHARFQRGWFWERGMLAYVSSGIGQTQLPFRLFAQPEVVLLEFAAHGADTHRPCDDPQ
RYVRERHGTGASGALR
>A0A4U3F788|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia persicina|TrEMBL
MDSLLKLPVASGSRVRILQITDTHLFAGKHETLLGVNTWASFNAVLEVIAADRRHYDLVV
ATGDLAQDHSMEAYQHFAEGISCLSAPCVWLPGNHDFQPTMFSTLAASHIADQKQVLVGD
HWQIVLLDSQVFGVPHGELSDYQLEWLEGALATEPQRHTLVLLHHHPVPSGCSWLDQHSL
RNPHMLDSVLQRYPQAKTLLCGHIHQELDLDWHGRRVLASPSTCVQFKPHCTNFTIDAES
PGWRWLDLYDDGRLETQVQRLTTRMFNPDLDSEGY
>A0A514V9S4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Leclercia adecarboxylata|TrEMBL
MESLLNLTVAGGAPVRVLQITDTHLFAKKHETLLGVNTWESYQAVLEAIHAQKRECDLIV
ATGDLAQDQTSAAYQHFAEGIASFNAPCVWLPGNHDFQPSMYSALQDAGISPAKRVHSGD
NWQILLLDSQVFGVPHGELSEFQLEWLEAKLAADPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLMKFPRVNNLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLQSTQFRPDTASEGY
>A0A2K4XCH5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudoalteromonas carrageenovora IAM 12662|TrEMBL
MAWFDEAYSFDKSSLNIAHITDSHLFADKSGEYFNVNTAKHFEKSLTHIAKQKPDCVIFG
GDLTQDHSFESYLLFSNLINQSVLTCPVFWVPGNHDELGMLNRISGAQINAAKRITANGF
DLLLINSKGPTPAGWITSNHLDEITQCLVSSSKSNVMFCHHNPLPINGYLDKHMLENGPQ
LLNILVNSNNVAALFHGHVHNEYTQSFRELAVYATPASSVQFVKNTVNWQQKNTGPAYRM
LNISSVKGELNVKTDVVWLSE
>A0A8B7LUC1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila elegans|TrEMBL
MRNCLPKFSKVFRRKSSSAKSSSASAGQENRSNDPDSDTEPYGIAVRPAAISISHQPGDN
RNERPLADDDSSRSRLISSAHLDFELDLALDLALESALHSEPPAMATNGGIRPKSEGSCP
EMKVETISAASPAPGASPGPVAISLPFVARNSSKTPEEMELEYEANAEAESRDIMTPLRR
NTRPLSVAFAGGGSVGGGRNALQPEIVEVIRSMDVPAMLLNNLSLEGVRDSMEGDRAGSH
PVAELSPGHDHEDSVVLRRKVNCLERKAHSLYERRLPKVPKLHLLVAGKKPTEEEEFRTF
QRNLMDLKYPTVLPPNPPLKALLVFHKSDSICEAITAACQRHQLDVTLVKSKEEALDTLQ
KSYATAQCYHLIIIDARSTKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIAL
LDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLL
RIQYANRATERLLNMRLDEIISKQLEDIFVSDLSTISEQCKNIKEFDGILTVRRKSQEGI
PMHVRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSI
ASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQ
MKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKSNPIIME
LLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYR
KSNTYHNSTHAADVMQATGAFITQLTNKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFL
CNSNDALAVLYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILAT
EMTRHFEHLAKFVSVFGGEEPREHNSQTDEETSILMRRMLIKVADVSNPARPMQFCIEWA
RRIAEEYFMQTDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQ
LITYMQINYSQWKKYDEQGVNTLAEIMAKQPPVGKMANSK
>A0A659SGW4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Poona|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELPANGVLETEVHRLQDTRFRPDTASEGY
>A0A1X7LSG2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cedecea sp. NFIX57|TrEMBL
MESLLTLPVADGGRIRILQITDTHLFAGKNETLLGINTWKSYQAVLTAILAEQRACDLLV
ATGDLAQDHSVEAYQHFAEGISRVSAPCVWLPGNHDFQPAMFNALQEAGISPAKRVYIGD
HWQILLLDSQVFGVPHGELSDFQLEWLERQLAAAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAAALDAVLKPWPQVKTLLCGHIHQELDLDWNGRRMLATPSTCVQFKPHCANFTLDTIE
PGWRWLDLYPDGSLTTEVCRLQSGKFSPDTASEGY
>A0A8E5IF95|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Dessau|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5J4S3X1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MKFFPIISALLLILGANFYVFYRLWVMLPASIVGRVLLVTFGVVALSSFVLVQVIGNNLP
LSLAALMYRVGTSWFFIFIYLLILFLLLELVRVTGLFPVIKFMHGSWYGLGVLAGALTLI
LTGGYITYLNKARVELSLTVNKEVGAERSLKIVAISDLHLGYGIGREEFEGWIKLINKEN
PDIVLIAGDAIDNSIRPLYERGIAESFKQITTKYGIYASPGNHEYIAGISSSLAFLKEAG
ITVLRDSVAFINDTFYIAGRDDRANSTRKSVEELTDTLDKSKLLILLDHQPYHLEQAERN
GIDLQISGHTHHGQIFPISWITEMMYEKAHGYLKKGDSHIYVSSGLGLWGGKFRIGTRSE
YVVIHLTPLKTL
>A0A5J4R4X4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MRKIYLLSLILVFSCSFQVLAQENIRIVHGPYLQNMGTNEVTIVWVTNKSAISWVELAPD
DGSHFYLKERPKVFASKNGVKLESRIHTVKLRGLTPATKYRYRIFSQEVTGRENHEITYG
KIASTTAYEPAAFVTIDPAKTAIAFTMVNDIHGRSGVLEQMLKWAEPMKNDLVFFNGDMV
SSLINEEDLFTGFMDVSVSAFAKNIPMYYARGNHETRGPFATSFQDYFSPLSPELYYLVR
QGPVCFVLLDCGEDKPDTDIEYSSITDYDDYRTLEAEWLRNALKSREFIDAPFKVVICHM
PPMNDWHGEAEILNKFVPLLNDAKVDIMLCGHLHKHIKLGANEQVKFPVLINSNNAIVKG
SITNKSLTLDVVGLDGKKTDSISIQK
>A0A5N7TGE3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp|TrEMBL
MPGAPVTAVEDSVLLVQLTDSHLFAEADGKLLGLNTGDSLARVVELAVAEQPRIDLILAT
GDLSQDGSVASYQRFRQLTERIEAPARWCPGNHDELGAMREAARGSALMEPVLEIGGWRV
VMLDTLVAGSVFGMLRGDQLDLLERALSEAPDHHHLVCLHHHPVSIGSRWMDRIGLRNPE
ALFEVLDRHDNVRALLWGHIHQAFDQSRNGVRLLATPSTGVQFTPQSEDFQVDSAAPGYR
WLRLYADGRLETDVSRVSGIDFEIDYSVKGY
>A0A7Y8YDC7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kalamiella piersonii|TrEMBL
MDSLLTLPAANGAGIRILQITDTHLFAGKNESLLGVNTWASYDAVLDAIAAQQREYDLII
ATGDLAQDHSVEAYQHFAEGITRLPKPCVWLPGNHDFQPAMVDTLAEAKIAAYKHVLLGE
HWQLVMLDSQVFGVPHGMLSDYQLEWLEKTLAARPQRHTLVVLHHHPLASGCTWLDQHSL
RNSHQLDAVLQNYPLARTLVCGHIHQELDLIWRDRRVLATPSTCVQFKPHCTSFTIDTVA
PGWRWFTLYPDGSFDTEVERLQTDAFRPDLDSDGY
>A0A8E6JBL7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Newport str. CFSAN000827|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A6L6Y3H0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Raoultella sp. 10-1|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRQCDLIV
ATGDLAQDHSAAAYQHFAEGIASFSAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQVLLLDSQVFGVPHGELSDFQLEWLEQKLAAEPERYTLLLLHHHPLASGCSWLDQHSL
RNAGALDRALAAFPRVRHLLCGHIHQELDLNWSGRRMMATPSTCVQFKPHCDNFTLDTVS
PGWRWLDLYPDGTLTTEVCRLSGVKFHPDIASEGY
>A0A0A7MG94|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinobacillus equuli subsp. equuli|TrEMBL
MNGFYSLGKKEPVVRLLQITDPHLFSAEHEKLLGVNTTDSFQAVLEQIRQTSFNYDLVLA
TGDLIQDHNPEAYHRFAEMVKQLAKPVFWLEGNHDRQPQMSLYLGKHPHIQSEKQILAGS
HWQILLLNSQVANAPSGNLSFGQLAWLNSKLAEYPDRYTLVVLHHNILPTNSAWLDQHCL
KNSNALAEVLSRYPNVKAILHGHIHQEVDADWKGYRVLATPSTCIQFKPNCDEFTLDLLP
QGWRELSLFEDGRIETEVKRLNSNAFLPDFQSKGY
>A0A1Z1NSW4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas salmonicida|TrEMBL
MILETELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQVNEHPFDLIL
ATGDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEH
WQVMLLDTQVRGKPHGVLGDHQLAALDSALRQHPERHALIALHHQAVPVGCAWLDQHNLK
NADDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGP
GWRYLTLHPDGRVASQVWRLPVGQFVPDPDATGY
>A0A8D8AUM2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Culex pipiens|TrEMBL
MWLNGLCCGGGLCGIGDVLKDHHHQQHQQHEEDGGPGDCGLAAALRGCPGGRCSTCTVMG
CTPSILSNSSGGSTSNGQQNRKDSGGIYGGVPASAAVTTTTTTSAATTGNDCIKKDSIVS
ITGLGPVSVVSSVLRRPTIGSGTSSSSGRHGPRQTSSLALTPEEEPLDSYPRLISDLKFP
NLWPPNPPIKILIAFCKNDPVFEALVTASHRLNFEPTFVKSHEAAIEAFQNVATGGHHII
VVDARHPRIIEADALGRSIRNSKGSQHTTMVAVVKKSVFEKDDTAVISLLDVGFNRCIIE
SPHVSICSSELRQIQHSLVRPQNVISTQQALYTALHRSREAIIITDDSLRAQYANRASER
ILNMKLDEIVGRSLSELVTADVSNILSQTSRHKDYEGFISTRRKSQETLHIHVRAVPVSC
IGRSPTHLVLILESPASGTTLSALASDALQTLPQGKEVARGSLHSIRRGSFDVRSIASDG
LRRTSLAKLSQLPLEAPITKVLSLLAQVQENCSQDESKLLDRVMEFLKREGLYSPQMKEI
RTEDPVATDLIGALLTQGPTNTISSRRSSNDSIIRGGGRPSTGSIVFTKTRESTQLNELL
SNALAWDFEIFRLEELTERHPLVCLGLELFRRFDVYNTFCCDENTFERWLHKMEEHYCSK
NTYHNSTHAADVMQATACYLQQLSNRELKVMDRMDEATALIAAATHDIEHPGRSSAFLCN
SDDRLALLYNDICVLESHHAATTFQLTLGDDKINIFKHLDRESYKLARSVIIDMILATEM
TRHFEHLAKFVSVFGTDVDAGKETTHDNEDNQILVRRMLIKCADVSNPTRPLKFCVEWAR
RIAEEYFTQTDEEKRKNLPIVMPMFDRTTCSISKSQIGFIEYIIHDMMDAWNSFIEMPEI
VRYMEHNYSKWKLFEEQGINTLNDIKRKQFTLNSSEAAGTTSSVEEL
>A0A1B9PNM8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aliivibrio sp. 1S175|TrEMBL
MLSETLLNNKSDLIRLLQITDTHLFAPEDGALLGIPTLYSFQSVVEQVQLLTPDFDAILA
TGDISQDHTVQSYQHFVNGIKPLKKPCYWLPGNHDYKPSMGGVLPSPQIKSSEHVLIGLN
WQLIILDSQVVGVPHGFLSIEQLDLLDNALSLNPDRHSLILLHHHPLPAGSAWLDQHKLK
DNEHLWSIIAKHTNVRGVVCGHIHQELDLMINGVRLLATPSTCVQFLPDSDDFALDSQSP
GWRILNLLPNGDIDTEVHRLAHSDFSADADAGGY
>A0A8B6HF14|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mytilus galloprovincialis|TrEMBL
MTQIIGVRKMKHANSFTGIVPKYGVEPTNADLLAQTLTDINKWGADVFKIAEYSGNRPLT
CTTYKIFQERDLLSMFKIPATTLLNYLMHLEDHYHRDNPYHNSTHAADVTQSTHVLLSSQ
ALDNVFTDLEVLAAIFASAIHDVDHPGLTNQYLVHTGSELALMYNDESVLENHHLAVAFK
LLQEDNCNIFLNLSDKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGVLM
LDNYTDKIQVLQNMVHCSDLSNPTKPIEIYKKSVDRLMEEFFQQGDKERERGMDISPMCD
RHNSTIEKSQVGFIDYIVHPLWETWADLVFPDAQEILDTLEDNRDWYQSMIPVSPSASFS
TRKRNSDKEEETKFQFDMDEVKDNNCDSAQTLKVSTPKTH
>A0A2J8T630|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pongo abelii|TrEMBL
MQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVR
SNVAALARLQCLGAAKQGPVGN
>A0A7C5PHF4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MHRTPLPPDCLKILQLTDTHLYADEQGRLLGVNTLETLRGAIEAFQGTGWRPDLVLATGD
LVHDASPEGYRRLAGLLDRFGVPVYCLPGNHDEPETMRRHLAGERVSCPKVVDHKDWRLV
LLDSVVPGEVGGHLAESELALLRDALEDGDQPTLVCLHHQPVPVGSQWIDSMGLDNAAAL
WALLDRAPRVKGLLWGHVHQVYDERRDGLRLMGTPSTCVQFSPETDEFSVDEQQPGFRLL
ALLPDGQILSEVMRVQQMPRGLEVASAGYD
>A0A6J3KIM7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bombus vosnesenskii|TrEMBL
MGCKTSMLECIEDTGEAEKRKHSDMVNQGSLLGKTEYDVLRRRSSFEDVAVDDDENADCS
ALKGPQNIEAHPLTNSVPSLIKILLVFPKDDQQMDVLATTSRRLGWSVSVAKDAEKAVEF
FQNRGHELVIIDHRGQRAAEADTICRAIRSSPAYHNSIIIALVKKSFLMHGEKDKIVTLD
LLETGFSRALMECSHERLLINELVGIYASALLPRTQLAAANALYVALDRCRDMVHVTNDK
HIVQFVNKISEKLLGYKTSEILGKSIADIVVYDNFVLMEQHISKGREFEGNMNCKRKNNQ
MITISCRVIPFSINLKKPTHYIYIYDTTYLSENIGSLSPTPSQSVYSRGNMIVSQRRTSD
MKSSEGRRRSSAHKLHSLQLDAPITKVISLLSNAITESTTPDTAAQIEKAIDILKTTELY
VPSLREDTDPVTTDLVGALLASPRKAWESRRSSVESTRVSMSKTFSTTTASRMQIKSFRG
PQEIAEILERCLEWNFDIFKLEILTEKRPLLFLGTTIMNMYRVPARLGCEEKVVQNWLTV
IEMNYQSRNSYHNSTHAADVLQATARFMQSERLQQILEPLDEVATLVAAAAHDVDHPGRS
SQFLCNSDNKLAILYNDLSVLESHHAALTFKLSLSDDNVNIFKNLERDTYKQLRQTVIDM
ILATEMTKHFEHLAKFMNICSARMMDSPQLDDYTDTVDMSVVLQPENVVLVKRMMIKCAD
VSNPTRPLKCCVEWARRIAEEYFNQTDEEKRMQLPVLMPMFDRATCSIPKAQIGFVDFII
NDMVEAWDAFIDMPEMVGYMRQNYEKWKEYNDRGISTLPDIEKIQELPELRIYQLPS
>A0A444UU40|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acipenser ruthenus|TrEMBL
MLNRELTHLSEMSRSGNQVSEFISSTFLEKQHEVDMPSPAQKEKDKKKKPMSQISGVKKL
MHSTSLTNSNIPRFGVKTEMEDSLAALHLTHISNLDRYKWRFQSGEMRESWNTLPSYSRY
TDSTVHIK
>A0A7C7ZM26|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cycloclasticus sp|TrEMBL
MNVFLPEKGDASDIKVLQISDTHLFATTDQQLVGVNTEQSFLSILQLAQEESWPPDLIFL
TGDLSQDASERSYTRLTKHLTALNIPCYVLPGNHDIPDTLTHIFSQQSVSYQPFLQHNNW
LFAFLNSETPNEEGGTLDEKAVAKLQLEIDRHPDKHVLICLHHQLKPVGSEWLDSMAVIN
PDSLIKLIGESPNVRGVIHGHVHQTFESDIAGKPIYAVPSTCFQFKPLCKEFAIDNIAPG
YRWLRLKANGQIRTEVIRLDKIPDNLEQHSAGY
>A0A558D9C3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sedimenticola thiotaurini|TrEMBL
MTQEITHIHRQPKDRSNQEMSLRILQITDCHLQADPEWKLAGINTQTSFEWVMDLASQDP
KRIDLILLTGDLVHDASVEGYRRLNQHIQSFGIRTCCLPGNHDKPAELYKHLTGGLIEAT
KVIDLGSWVVVMLDSTIPHSEGGHLRDQELELLQQSLHDYADRPVLIALHHHPIKINSAW
MDNMALDNPGPFLSILDQNKNAKGVIWGHIHQNFETVYNGIQMLGTPSTCIQFVENQDSF
GISTAPPGFRWLELRPDGSISTGIERVAALPPGLDLKTAGY
>A0A2J8KKW4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pan troglodytes|TrEMBL
MAQQTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISP
RNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVH
SQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALT
NLQDRAPSKRSPMCNQPSINKATITGLYNGIIAFL
>A0A564FV78|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium dankookense|TrEMBL
MTDTPFRLAHLSDPHVGPLSRPRLRQLLGKRATGYANWRRGRSRSHDMEVLAALVADLRA
QDPDHIACTGDLCNIGLPSEWETARVFLEALGAPGAVSFVPGNHDAYVRGSLEGLLAACD
GWTADDGGLGGCFPYLRRRGPLAIIGLSTAIPTKPFVASGRLGPAQIAAAEAVLRALATE
PGRPCRVVLIHHPPHPGGALPGRELTDAKALAAMIARTGAELILHGHNHVTSLAALTGPN
GVPVPVVGASSASARPGAHGPSPARRAAYLLFSFVREGGRHVITARQRGMDPDGNVADLG
ALALV
>X0NYX4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium leiognathi lrivu.4.1|TrEMBL
MFANESGSLLGVATQNSFHAVLDAVDTVAREFDAIVATGDISQDHTPESYQEFAGGIARW
SQPCFWLPGNHDYQPTMASVLPSEQIKPCEQVLVGEHWQMILLDSQVAGVPHGQLSQAQL
ALLDSALSQYPERHALVLLHHHPLPAGSAWLDQHQLHNNNALWEVVEKHPQVKAILCGHI
HQELDRMYRGVRVLATPSTCIQFLPDSDDFALDQENPGWRYLELTPKGDVITHVHRLEGD
QFKPTFDAAGY
>A0A7U7EG41|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas stutzeri|TrEMBL
MPGAPVTAVEDSVLLVQLTDSHLFAEADGKLLGLNTGDSLARVVELAVAEQPRIDLILAT
GDLSQDGSVASYQRFRQLAERIEAPARWCPGNHDELGAMREAARGSALMEPVLEIGGWRV
VMLDTLVAGSVFGMLRGDQLELLERALSEAPDHHHLVCLHHHPVSIGSRWMDRIGLRNPE
ALFEVLDRHDNVRALLWGHIHQAFDQSRNGVRLLATPSTGVQFTPQSEDFQVDSAAPGYR
WLRLYADGRLETDVSRVSGIDFEIDYSVKGY
>A0A3P3VJ00|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aestuariirhabdus litorea|TrEMBL
MQITDCHLFADADGRLMGVDTSQTLDWVLELARSLPSPDRLLLTGDLAQDGTPDSYRLLR
ERIAPLNVPSHWICGNHDNALAMAEALADQPQTLSKRIVMGSWQLLMLHSQVEGEVGGAL
AEAELELVERSLRAFKGHSLICMHHHPLAVGSQWMDRIAIANQQQLWERLALAQGQVILL
CGHVHQHQERRHQGVTLLTTPATCFQFAPLSDSFGVTEEMPGLRTLELYDDGSFDTQVHR
VSPHELTINRELMGY
>A0A2I8QY28|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sp. ASNIH3|TrEMBL
METELPQAPDGSVRLLQITDTHLFASAEGRLLAVPTAQSLAAVLERVQANEHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGDHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHHGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRVASQVWRLPLGQFVPDPNATGY
>A0A250VPR3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces olivochromogenes|TrEMBL
MLVLAHISDLHLDGSRRASERAERVRDRLWELPGRVDALLVTGDIADHGTEAEYEEAARL
LGLRDGEPPFPVLTCPGNHDSRAPYRKALLGQPVSEGPVNSVHLFDDAAVLMCDSSIPGQ
DEGELDEETYAWIETTLDELDGAVPALLAFHHPPVALHHPLPDAYQLRRPASLAALLERR
PEVAGLITGHAHTPAATAFAGRPLVVGPGVTWTLRLPWEGEGAADRDAPPGFAFHVLADD
GRLTSHFRTV
>A0A7X6W619|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Halopseudomonas formosensis|TrEMBL
MTSDAQGFPGSVCVVQLTDSHLFADAQQRLLGIDTLASLNAVVDQVLVEQPRIDLVLATG
DIAQDASPQAYHSFIRTVGRIPAPCCWIPGNHDDATLMAEIGDAQGLNRDWVDVGAWRIV
LLDSSVAGSVSGVLEQPQLLQLDRALDSAGERHLLLCLHHHPVPIGSAWMEPLGLQNADR
LWQRLDAEPRVRAVLWGHIHQQLEQQRGSVRLLASPSTCVQFAAGSSDFATDQQAPGYRW
LRLHDDGRMETGVSRLAPGSFPPEAGASGY
>A0A523P8V9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteobacteria bacterium|TrEMBL
MTRAALHVLQFTDTHIFADEAQLFGGVNTRCSFLAARDKALAERRRCDLILITGDLAAQA
DGGAYSWLAAQLLMFEVPIYCLPGNHDIGEVMQPLVCAAGWNFGGSLTIGGWQIVLLDST
VRGEAYGHLTASELGALDDALARHPNLPTLVALHHQPVPIGSVWMDAMKLQDAARFWTVI
DNYPQVRGVLWGHIHQNYDAFRHRVRLLATPSTCVQFAARSVDFAIDSLPAGFRWLRLSS
GGDIATDVVRV
>A0A523NQY6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteobacteria bacterium|TrEMBL
MTRAALHVLQFTDTHIFADEAQLFGGVNTRCSFLAARDKALAERRRCDLILITGDLAAQA
DSGAYSWLAAQLLMFEVPIYCLPGNHDIGEVMQPLVCAAGWNFGGSLTIGGWQIVLLDST
VRGEAYGRLTASELGALDDALARHPNLPTLVALHHQPVPIGSVWMDAMKLQDAARFWTVI
DNYPQVRGVLWGHIHQNYDAFRHRVRLLATPSTCVQFAARSVDFAIDSLPAGFRWLRLSS
SGNIATDVVRV
>A0A2U3XXN7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Leptonychotes weddellii|TrEMBL
MKKSRSVMAVAADDNVKDYLECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQS
ETARTPEGDGISRPTTLPLRTLPSIAITTVSQECFDVENGPCPGRSPLDPQASSSSGLVL
HATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVR
NNFTLLTNLHGASNKRSPAAASQPPVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTY
RSVSEMASNKVRDDRFILESSPAPLGSPGLCLRQRCIRGRRRSE
>A0A3R7KYN7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trypanosoma rangeli|TrEMBL
MSEIPGLPVQKGRSDGRSDSCATCGNKFSPPTAKSNCPCCEKLCCSDCVQAECAIVAGSA
SSKVCIDCFSMLQSNRHTGPVESSPSPEFYAASVSPPRSLTPANGRERSAAAHARASGDE
RTQDALAVDGECASLSVFQQYVGDPKHSEFLQTKSDSLLRHLRERELELQSLRVERDRAI
APIAPGEKCIWNKTEVQQTSEENAKELREQLDSAQLRMGAMETELKKALDRAKSSEATVQ
LLQQRIGRYEDEVARLQQSQKGLETAPGSVHKDTLWTRKLHPSIVQDTVLTVVTPKSCEA
SGLDVNLRDWKFDSFEVASRVPSVLQSVAMNVALAWNLFSSHDEFQRWVMLVAAVENNYR
PNAYHNAIHAADALQGVFYLVTSATPLMEHMTPLELKAAAFAALVHDVRHPGRTSGFLAA
VQDPVSYKYSGSGSLEQLHVATAFELLTVPEFDFTSSMDNASFLEFKNIVTHLILHTELR
LHHDIISKLGAKVGAGRLDCTRKEDRLDALSFILHAADIGAPSRGVAIARRWLVVLQEFA
DQAEDERRRGLPVTPGFDTPSLVESSQIAFLDFFVIPTFDLLHQLFSSIEEPLHNLRKLR
EVYAAKAGVKTPFPPPVDYRGQEEKSQRLEAGLAEHRSQGREFYRLLEELKTAGINLKRK
SAALRTKEEELIKRSCLQGQGEGRWKFDPAKTGDELQTEKEMRGPQQVYIDPLRNETVEA
TAGRDGTRDQVGGWSETIEARERKLREREAALMMSARSMDIREKKLAAFSEKLADIAERL
HAEQKRVRETENPAVALPHRESLLVATGDADINMARPSLAQHEAEERLAKKYNEVDELLL
MVRAMRIECVAISGTDVRQRALSATLAEREAAIAEAVELSRQRRRQAEEGRGLRPTSMQL
SRLESAIFQLTAAITLLAE
>A0A1A6IVK7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio tasmaniensis|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSHNFDYQAILA
TGDISQDHSAESYQKFESGIQPLAKPCYWLPGNHDFKPNMGSVLPSPQIQCVDHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLSEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAVLCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTEVRRLPHGQFLPDFAAGGY
>A0A4Q6DGH2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moraxellaceae bacterium|TrEMBL
RESDYDYLICTGDIASAGHSDCYKRFVDIVRGYSSRPLAWLPGNHDSAAMMESVTFANPP
QAHCVIQDNWMILLLDSVVPKKVHGNFEQTELDYLEEMLSAHPDKHVIVMLHHQPVLVGS
AWIDQYIVRNADDFFAVIDRHSNVKAISWGHVHQDFRAKRNGIELIATPSTCVQFKPLCD
DFTVDTLMPGYRWFDLHKDGTFDTGIHRVTGKHYVIDYKSAGY
>A0A853NXM2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIEPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQIDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAVLCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTQVRRLPNGQFSPDFDAGGY
>A0A2S7UJ79|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MELSHTSKFDESSIKLVQLTDTYLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGER
WQMIMLDSQVVGVPHGRLSDQQLDLLEQKLAEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHSNVKAVLCGHVHQDMNREHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPHGQFLPDFKAAGY
>A0A2A2MTA3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio coralliilyticus|TrEMBL
MKVTSCSSDGSIRLLQITDTHLFEATDGSLLSVNTADSFNAVVDAIVEESPAYDAVLATG
DISQDHSEVSYQRFEQGIVPLKKKCFWLPGNHDFKPSMNSVIPSQQIQQIDHVLLGDTWQ
MIMLDSQVVGVPHGRLSDKQLNLLEEKLSQYPERYTLILLHHHPLLVGSAWLDQHTLKDS
DDFWQVVDQHNNVKAVLCGHVHQDMNVMRNDVRVMATPSTCVQFKPNSDDFALDYQSPGW
RELQLRDNGEVETQVKRLPAGCFQPDFNSAGY
>A0A444JLN6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium chitinilyticum|TrEMBL
MQMYSLPQTNPDSVVLLQITDTHLFANEAGSLLGVATKDSFHAVLDAVDTAARPFDAVVA
TGDISQDHSELSYQRFCDGISRWPQPCFWLPGNHDYQPSMSSVLPSPQIKPCQQVLAGDH
WQVILLDSQVQGVPHGELSEAQLKMLDQALASHPQRYALVLLHHHPLEAGSAWLDQHKLQ
NADAFWQVVDKYPQVKAILCGHIHQELDRIHHGVRVLATPSTCIQFQPDSNDFALDKLNP
GWRYLELMGDGRVLTSISRLQGRCFTPQFDAGGY
>A0A5P2SLT5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas luteola|TrEMBL
MALATSPDFLAAPLVVQLTDSHLFSSPEGRLLGLDTRYSLEQVVERVRAEQPTIDLILAS
GDLAQESTPEAYQSFKELTACLDAPARWLPGNHDKVKVMQTFCAGTDLMDPVLDMGQWRL
IMLDSTINGAVPGRFDQEQLELLEKALSEAPDRHVLVSFHHHPVQVGCQWMEPLGVLNPE
ALFEVLDRYSQVRVILWGHIHQEFDQIRNGVRLLASPSTGLQFEPNSVDFKVGMQAPGYR
WLRLLPDGTIETGISRVEGVDFNVDFQGSGY
>A0A8C5XW73|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcebus murinus|TrEMBL
KRMLSRELTHLSETSRSGNQVSEYISRTFLDQPAEVELPRATSEEPAGPMSRISGLRGPR
RGASLSPATVPRFGVQTDQEGQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQAV
FTDLEVLATIFASAIHDVDHPGVSNQFLINTHSELALMYNDASVLENHHLAVGFKLLQAE
NCDIFQNLSPRQRLSLRKMVIDMVLATDMSKHMNLLADLKTMVETKRVTSLGVLLLDNYS
DRIQVLQNLVHCADLSNPAKPLPLYRRWTERIMAELFQQGDRERASGLDVSPMCDTDSTV
GFIDYIAHPLWETWADLVHPDAQGLLDTLEDNREWYLSKIPRSPPDLSSPERGGPDRFQF
ELTLEEAEEEAEEEAEEEEEAALDSKASESRDTKLLSPGASQKPSDLPADGHRT
>A0A221UWD6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arenibacter algicola|TrEMBL
MQNQEKGRRKFMAKMGLGTLAIGMGNVGAYAFAPKNEITKKNKVNIGFITDVHHGFCADG
LERLQVFIKEASSRKLDFIIQGGDFCFATEEARECMDLWNTYKGEKYHVLGNHDMDKVTK
KEAMDFFGMESNYYSFDKGDFHFVVMDGNYILKDGKYEDYGNANFYIDQQNRSLVNPEQI
EWLREDLEKTDKQTIIISHQAFDEIWDGWSSPSRFEVRKVIDDANNRTDYQKVIACFCGH
HHVDDHSYINNVHYFQMNSASYFYVGEGYGSDGSRAMYEDSIFAFLTLDPSGKISIEGRK
SQFVRPTPMEKGHPDAPRLSASISDRSVGFKKKV
>A0A4P6LXY2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Blautia producta|TrEMBL
MLAIILAPFYLLINYYVVRWMIRWTGTCHRHLKSRPFRAVFLCIYIFMCLTPLTSYLVSV
NPWHSWLKRLFNYWLGTFLYIVLIIIIFDIIRIILKHTNWIKNETLARRRTFILSGGAAA
CLIICLSAYGIIHEHRLYVNHYEARVEKSGGKLDHLRIALTADLHLGYSIGTYHVKSMVD
KINAENVDLVCIAGDFFDNEYDAVQYPEKTISILKNLKSTYGVYACWGNHDFKEKLLAGF
TVPVKNGQHTDARMDDFLEQAGIRLLDDKSVLIDDSFYLAGRKDPQRSKKMKEDRLSPDE
LLKDLDQDKPILVIDHQPKQLQELADAGCDIDLSGHTHDGQMFPGNLTTKLMWENSWGEL
KKDNMYSYVTSGVGVWGPAMRVGTDAEIMIIDVYFTK
>A0A7H2UWY8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter seifertii|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIKQILKQHPEADAIIHT
GDLAQAPTPLTYKRYINFMQTLGLPFFHTLGNHDNVDHFPLHNENHQEPVVVGLGNWRII
MLNSAVKGKIDGHLSSEQLKNLANLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFKNVKALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSKDFALDQNAPGYRY
IRLNNDGTFETKVFRLENFKTLINTDISG
>A0A679KFN4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium bullatum|TrEMBL
MTHSAMTHPAMTHPASARDDILAFAHIGDLHLTEGHLKNARDFLAIVAQLGAVEGLDFAY
LPGDNAENGLPEQYALVRQGLLGFSLPVHVITGDHDMEGGSLDAFHAGLGARPLPYATDI
SGIRCLFLDMCGPGTGGPDFRLGDAQLAWLEGEIQLAERDGLDCALFMHSYPADLKGEGE
AVRVGHLVSQSRVRLVEMGHTHYNELANDGRTIFAATRSTGQVEEGPVGYAIAAIDGGVV
SWRFKELAEPWPFVLVTAPADRRLAHDDGHRVRDTVEVRALVLGASAVTACEVRVDGGPW
QAMTRADGDRRYRASIPWDASGRRLTVRASDAAGGTGQDVVEPATDRSRLPVSKGIGSDA
DSIGAWPEKGLLGTQLGPNRNGRHW
>A0A502GKV1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ewingella americana|TrEMBL
MESLFKLPLVNGAKVRILQITDTHLFAGENETLLGVNTFRSYRAVLDAIKAQNREVDIIA
ATGDLAQDQSLEAYHHFAHGINELPAPCVWLPGNHDFQPAMVDALQAAGIHPSKQVLLGD
LWQVLLLDTQVFGVPHGHVSEYQLEWMERCLDAYPDRYTLIMLHHHPLPSGCTWLDQHSL
RNAHMLANVLARYPKVNTLLCGHIHQELDLDWYGKRLYATPSTCVQFKPHCTNFTIDTAA
PGWRYLDLCPDGRVETQVFRLDTDEFSPDTDADGYE
>A0A8C6XRQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Naja naja|TrEMBL
LGCLQPQGGERLYSFPYLFAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKVG
TPVCFHLSNHPPSHPASSVLLCLALFSPPNLDNSEGNLTSISALGEAVCNRTAIS
>A0A2T3JLW5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium phosphoreum|TrEMBL
MQTYSLPQTNPESVVLLQITDTHLFANGSGSLLGVATKDSFHAVLNGVDAAARHFDAIVA
TGDISQDHTPYSYQRFADGISRWSQPCFWLPGNHDFQPTMQSILPSEQIKPQQQVLVGDH
WQMILLDSQVQGVPHGELSAAQLVLLDAALARYPDRHALILLHHHPLEAGSAWLDQHQLH
NNSGLWTVIDDHPQVKAVLCGHIHQDLDRTYHGVRVLATPSTCIQFMPDSDDFALDHNNP
GWRYLELINDGQIITSVHRISGDQFKPKLDAEGY
>A0A556RKK1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gilliamella apicola|TrEMBL
MLESLLKLQIRNKHCAKILHITDTHLFESEDGALLGVKSNASFLSVINEIKHSNKKYDLI
VATGDFVQDGSMKSYARFAEQIKQFKIPCVWLAGNHDNYSHMQEVFSNYQLAENKLVMLG
DNWLIVLLNSQVFGQAYGWLSESELQFLEKTLLSYPDKNVMVFLHHHPINSGCHWLDKHI
LKNSCELEKIVKKFSTFRGLGWGHIHQQQDHVWHNCHAFSTPSTCFQFKPNCYDFQLSNE
DAPGWREISLNEDGTLETSVFRIADNQFLPDISQKGY
>A0A1B7IXB4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Buttiauxella brennerae ATCC 51605|TrEMBL
MQITDTHLFSGKNETLLGINTWMSYQAVVDAILAEQRHYDLIVATGDLAQDHSAQAYQHF
VEGIAGIPAPCVWLPGNHDFQPAMFSSLLEAGISPAKQVFLGDSWQILLLDSQVFGVPHG
ELSDYQLDWLERKLAGAPERHTLLLLHHHPVPAGCSWLDQHSLRNAAELDNVLQKFPKVK
TLVCGHIHQELDLDWNGRRMLATPSTCVQFKPHCANFTLDTIEPGWRWLELHPNGEVTTE
VCRLKGAVFNPDTASEGY
>A0A4W5JNC5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hucho hucho|TrEMBL
MALCVCIRRPLHFAEPPAVTGHRRHRSLPLSLPPLTFDVENGPSASCSPLDPSASPGSGL
VLHTNFPGHNQRRESFLYRSDSDYELSPKSMSRNSSIASELHGDDLIVTPFAQVLASLRS
VRNNFTVLTNVQCASNKPLPNELCINKGKIQMSLNTQQL
>A0A7J0A7U5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacteroides acidifaciens|TrEMBL
MKRLSVILILFLLYLPLSAQFKGTVYIDTDQSDIFNKGDKPLAGVMVTDGLNVAKTDKKG
RFSLPGFEKTRFITITTPAGYETQHFYLPVTENRKSYDFLLTESERTKSKEHSFVQITDT
EVTSGMGRWVTDLQQYIKNEKPAFLIHTGDICYEAGLTMHNRVVNAQTMDCPVYYCIGNH
DLVKGKYGEELYESLYGPTWYSFDVGNIHYVVTPIDHGDNPTDYTLKDVYNWLKNDLALM
KEGQALILFNHDLFTASDTFVFKADNEHMLDLRAFNTKAQIYGHMHYNYVRNQNGIYTIC
TGTLDKGGIDHTPSSFRAIKVDANNNISTELRYAFIEPQIAIVSPMDNQTAASSAAASTG
ENQLPVSVNTYHSQAKTSHVSYVLSDAENNQEIAKGNLTSLTDWNWNGNIQIPTNENRKR
LHLTVTSFFNDGKKATATSQFTYQKDFKLSSIPGEGWNTLLQNAAHSGGVNDSQIKLPLQ
LQWTTNTGSNIFMTSPIIAEQKVFIATTDDNVSLNTFIYAFDFNSGKLLWHRAANRKSTS
TKRTIGQSGRYIHPARHRTGDYLWHRRPRSVRTGQIHTFQ
>A0A6L9ZU83|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Okeania sp. SIO3B5|TrEMBL
MYGIPTESSFVKVLEKLKQLQTQPDVLILTGDLSQDETSESYQRLASLLSPLGIPTYWIA
GNHDNLPAMERVLNSAPISATKSFEMGGWNFFLLNTNVPGLVYGEISPESLEWLEYNIKM
TGNKPVLIALHHPPVKINSEWMDKILLHNPENFLNIINRYPQVKIVLSGHIHQEFAKEIN
GIHYLSTPSTCIQFEPENPNFFLDKQPPGLRLVTLYPDGNHTTKIERIDYIYECDMAARG
YN
>A0A060XQH2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oncorhynchus mykiss|TrEMBL
MLEELDWCLDQLETLQTRHSVSEMASTKFKKMLNRELSNLSQMSCSGTQFSEFISRTFLD
KQHSAERPCPEMQKVKTDKKNAKPMIQMSGVKTTSLSNSNIPPFGVKAGTDDKLATELED
INKWGLNLFKVTELSGNRPLTVMMHTIFQERHLFKTFKIPLDTFITYLMTLEDYYHGDLA
YHNNIHAADVTQSTHVLLSTPVLEAVFTDLEILAAIFASAIHDVDHPGVSNQFLISTKRV
NSSMWCAVTPSELWLLTKVQCSPMRATAVACFNCSAFVQLVCSCNDGGSRG
>A0A3A3ZRG6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter chuandaensis|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLAKYPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLAGAEFRPDTASEGY
>A0A6I1VVP1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. FSL R10-0071|TrEMBL
MPNVSTLTTEDPVLLVQLSDSHLFAEADGSLLGLKTAQSLQQVIDLVQAEQPHIDGLLAT
GDLTQDGSVEAYQRFRTLTAPLAPFGRWIPGNHDQVAQMREAAVQSRLLEPVVDIGNWRI
TLLNSAVPHSTPGYLEDDQLQLLAQSLSEAPDRHHLVCLHHHPVSVGCPWLEPIGLRNAK
EFWSVMDRYPQARAVLWGHVHQAFDQQRNDVRLLATPSTCIQFAVGSPDFKVSGEAPGYR
WLRLQPDGTLQTGVSRLADFTFEPDYSANNY
>A0A3Q1APC0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Amphiprion ocellaris|TrEMBL
GFMGSSCTDNGLSVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKAMS
RNSSTASDLHGEDMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNKRPSSSNQPSMCKPC
VAGQC
>A0A679K237|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hyphomicrobium sp. ghe19|TrEMBL
MISRRDLLKLTGVAGVGSTALSGYALAEAFRERVTSYNLTLPNWTPGLKLKFAVLADLHV
CEPWMSVERLEVIVEQTNKLGVDAVLLLGDYVVGHRLGKYSGRVSNGAWATVLSRLKAPL
GVHAVLGNHDWWESRDVQKKRAGPTPAGLALQVVGIPVYENNAVRLEKDGQAFWLAGLGD
QWAFWPRSDEYDEFVHGGKIAYRGVDDLPATLRQVTDSAPVILMAHEPDIFPKVSDRVSL
TIAGHTHGGQVRIFGYAPVVPSRFGSRYAYGHIVEDKRHMIVSGGLGCSSLPIRFGSPPE
IVVIELGGSERGEV
>A0A0P7YGQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Scleropages formosus|TrEMBL
MKEHGGSALYGGALGSPPATVDTLQPDYVSVRLLAEESYQKLAVDTMEELDWCLDQLETI
QTYRSVSEMASNKVGRGHDTCREMPLASKATYFSQDTCVCGGL
>A0A0J1Q9M9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. MGH109|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A6J5IFL9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter insuavis|TrEMBL
MLIAQITDLHMRTPGDKAYGIIDPAAFLGPAVRALNALTPRPDCVLITGDLTDLGKAHEY
QALREQLQALEIPYFLLPGNHDDRAQLRAAFPDHGYLQGQGPFIQYAVETYPLRLLALDT
VVPMKSHGELCDERLGWLAARLAEQPDRPTLVLMHHPPFLTGIEHMDAIGLLAGAPELER
IVARYPRVERVLCGHLHRTIFRRFGGTIASTCPGTAHQLALELGPRPTLQYIMEPPGYQL
HWWHDGALVTHHAVIGEYPGPYPFA
>A0A1E1XMT9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Amblyomma sculptum|TrEMBL
RPQCLEGPLRRAANLGEIVTDRTVPLLAKLDGSTPDDGRKGTVALKFGSMYLTVPSIKVM
FVFGKEDAQYNALKWAAEKMHYECTLSSTSEAAIDNYLNGQPHLVFVDARSKSAIDPVTL
CRTLRGFRGSQFTCIVAVVKKGLADKEEAAVIPLLKCGYNRWFTETCSLGVCLNEMIQIE
HNDLISLWKLRASEALFSALHYTRDGVIVTGASHEIQFMNRAAEKLVGYSVEEMLGVDAQ
ELHRTDSLKTDVASNINMQLKKGKEWEGTLFHKRKSGECIPMWSKIAPVEIHTGKSDHVV
YIKECPFFMEKPFSPDAVGMNRRQSFAKFHAMTLEAPITKVINMLVSTQENSSAMVAQAL
DRVIDILRSTELYNPQLGVGQGKSEDQMTSDLVTGLINTGQKPTGVRRLSHETSLMKVNV
VNATAPSGVLPSLNTAPPKIKELLENDVKWEFDIIELETLTGRRPLIWLGLSLFSKLNVH
TSLECDDATIRNWLQLVESHYLDNPYHNSTHAGDVMQATAYFLLKLRKKDIFDPLDEAIC
LISAVVHDIDHPGKSSPFLCNSDHELAILYNDRSVLESHHAAFAFKLTLSDEKVNIFQKL
ERDVYRSVRLSIIDMVLATEMTKHFEHLSKFLNAFQKPMQEEEGFESEPLQEHGESGSLR
SAENIILIKRMLIKCSDVSNPARPIQLCIQWAHRIAEEYCAQTDEEKRRGLTVVMPAFDR
ATCSIPNSQTGFINYFVRDMFRAWSDFGEFPELMEYIEKNYIYWKDKEPSPGQQGNR
>A0A5N5KLC1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pangasianodon hypophthalmus|TrEMBL
MEVPPCSKKSLSLSLPVPREGQATLKPPQHLWRQPRTPIRIKHRGYSDTDRHHHPHMERA
DAMDTSDRPGLKKSRMSWPSSFQGTTSTSTGNCAGNKRFEGENGPSPGRSPMDLQASPGL
VLHPSFPQSGRRESFLYRSDSDYDMSPKTMSRNSSINSEGHAEDLIVTPFAQVLASLRTV
RSNFTILANVTSPTDKRSPVTSQSTVPPATLSEETYQQLARETLEELDWCLDQLETIQTH
RSVSEMASNKVCFQLFLQHYH
>A0A822AGB2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ranitomeya imitator|TrEMBL
FDVENGLSAGRSPLDSQASPGSGLVLQGNFPHSQRRESFLYRSDSDYDLSPKAMSRNSSI
ASDLHGEDMIVTPFAQVLASLRTVRSNFAMLTHLQDRVSNKRSSGNNPPTACKSNLSEDA
VQKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSETSRSGNQVSEY
ISSTFLDKQHEVEIPSPTTKEKEKKKRPMSQISGVKKLTHSSSFTTCSIPRFGVKTDQES
LLAKEIEESNKWGLDIFKVAEYSGNRPLTVIMYSIFQVRE
>A0A2T9VBZ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. HN503E2II|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAEHRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSAPCVWLPGNHDFQPAMYGSLHDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVNNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLTGAQFRPDTASEGY
>A0A7K0DST7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nocardia aurantia|TrEMBL
MTGQEGMSRRELLRHSAWFGAAVGLSVAGGAVVAQVAGPPAARAETARPDLRFVQLSDSH
LGFQGPANADVTASFAEAIGRVNALGYAPDFVIHTGDLTHLSTPDQFDQVKQMLLGLNTP
HVFTVPGEHDSVDDAGQKYRAVFGHGTRGDGWYSFDIAGVHVIALVNTLNLQSLGHLGTD
QVDFVRKDVAGLRSDTPIVVFSHIPLFAMYPQWGWGTDDAMQVLSLLSRFDSVTCLNGHV
HQLFSKTEDKVTFHSATTTAYPLPHPGDGPAPKPVTLPPGQLHAALGVREVSYRKGQRSL
AVTDTPLP
>A0A2H5XH67|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR18|TrEMBL
MRLLHLSDLHFGRLASQTIVADLLAEARRQAPDLVVVSGDLTQRARPRQFQAARAFLEAL
PAPWLVVPGNHDVYPWWRPLSRLWRSLARYRHYITQSLRPSWVTDTIALLGLNTAHGATI
KGGRLTTEDLTYLQTFFAAAPPQALRILVIHHHLVHLQDIGPHDVVRDARQALEAVAQAG
IHVILCGHLHIAHVAPVLLQPQWQLLVVSAGTATSSRGRGPHRHQNFYNLLEVTPQTLRI
ETYRYHPEARTFTLTQTQTFERQGAQLLLETAQTG
>A0A2H5V804|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|archaeon HR04|TrEMBL
MLLVQLSDVHVSNGFRRDMLEQAIDEVNSLAPDVVVVTGDITDNGILQEYERARAYINML
KCKNMIMLAGNHDYRNTGYLLFKRFFAPKQVYEDDQCIITTLSTARPDRDEGEVGYRQNL
WLFNTLTDASKDGKVKIIAMHHHLIPIPDTGSDRIIVLDAGDVLQTALEAGVNLVLCGHK
HRPWIWQLGSLTIAYAGTVSSERMRGFFKNSYNIIDVHRDRVEITLKVVGGESMSLKDIV
KAREVVMEG
>A0A8D4RD08|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNLFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQAVLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLVPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTQVKRIQQAEFLPNMQEEGY
>A0A6G8NVZ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Caballeronia sp. SBC1|TrEMBL
MTLLLQISDPHFGTEQPLVLAALLRLANTLQPDLVVISGDITQRARRAQFSAARAFVGTF
GATPFVVVPGNHDIPLYNLFARVAHPYANYRRVFGDDLEPVFESAELLVIGVNTTRAYRH
KDGEVSAQQVERVVRRLEHATARQLRVVVTHQPVAAARANDIRNLLHGREHAIERWSQAG
VDLILGGHIHLPYVAPLHVAYKDLPRQMWAVQAGTSLSSRVRGSVPNSVNVIDYDTSNAG
TRRALRRLVVTRWDFNRAIASFTPNMQHELDLDSGSLKTPLATLL
>A0A3J4LEJ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYGALQEAGISPAKHVLIGE
EWQILLLDSQVFGVPHGELSEFQLEWLERKLANAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSLLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A7Y1HU18|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas oryzihabitans|TrEMBL
MSLPDSVNAPLVVQLTDSHLFARANGRLLGIDTAASLQQVVAQVVREQPRIDLLLASGDL
SQDGSVASYQRFCELTEPLAAPMRWLAGNHDENAPMAKACGDRDFLETVTDLGAWRLILL
DSTVRGCVFGELEQAQLIALDEALSAAPERPALICLHHHPVPVGCGWMEPLGLHRADELF
AVLDRHPQVKVVLWGHIHQEFDQLRNGVRLLASPSTGLQFEPGSEDFKAGDQAPGYRWLR
LLPDGNLETGVSRLQQHAFTVDHSAAGY
>A0A077P4V8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus bovienii str. oregonense|TrEMBL
MESLLKVPVAEGATARILQITDTHLFANKGDALLGINTYRSYYAVLDAILEQSIDIDLIV
TTGDLVQDQTIGAYQNFAEGIARLPVPCVWLPGNHDYQPAMVDVLAAAGISPSKQILIGQ
HWQLVMLDSQVQGVPHGELTDYQLEWLQKCLDEHNERNTIVMLHHHPVPSGCTWLDQHSL
RNAPALAESLKDKRQVKAILCGHIHQELDKMWNGIRVMATPSTCMQFKPHCTNFMLDTVA
PGWRYLELSVADNREAKLQTQVHRLKSNEFCPDLDSDGY
>A0A0T9L0R3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia nurmii|TrEMBL
MESLFELPMASGARVRILQITDTHLFAGEDETLLGVNTGRSYRAVLDAIIAEKYPYDLIV
ATGDLAQDQSIAAYQHFAQGIARLSAPCLWLPGNHDFQPAMVDVLAEANIAPSKQAFVGN
NWQILLLDSQVFGVPYGELSEHQLEWMERCLQAHPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLADVLIRYPRVTTLLCGHIHQELDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGTLETEVRRLDSDEFNPNMDADGY
>E1SWM1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ferrimonas balearica (strain DSM 9799 / CCM 4581 / KCTC 23876 / PAT)|TrEMBL
MTICVDTLTPKDENGVIRLAQISDPHLFANKAAGFLGINPWQSLSAVVEQLAEEAPLDLL
LVTGDISQDHSATAYLHFADAVAPLALPTYALPGNHDAPKLMSETLRDTSVQYGRRILAG
GWQILLLDSTVLGLPAGHLALDELRWLHGVLNSTESCPTLVALHHHPKPTGCAWLDQHGL
DNGVEFLSLLSRFPQVKAVLWGHVHQEMDLWHEHIRLLAVPSTSIQFLPKNDGFALDLAQ
PGYRMLNLHPDGTLTTEVKRVAGSAFLPDHSATGY
>A0A291TLF1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sp. CU5|TrEMBL
METDLPQAQDGSLRLLQITDTHLFASQEGRLLAVRTAESLAAVLEQVQANPHPYDVILAT
GDLSQDHSPESYQRFASMMAPLGRPIYWLPGNHDDSPLMTEYLHAAGISEAKQLVGDHWQ
VILLDTQVRGKPHGVLGDHQLAALDRALRQYPDRHALITLHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHHGVRLIASPSTCIQFKPLCDGFALDESGPGW
RYLTLYPDGRVASEVWRLPVGQFVPDPNATGY
>A0A8C6GWQ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus spicilegus|TrEMBL
MTAKNSPKEFTASESEVCIKTFKEQMRLELELPKLPGNRPTSPKISPRSSPRNSPCFFRK
LLVNKSIRQRRRFTVAHTCFDVENGPSPCRSPLDPQAGSSSGLVLHAAFPGHSQRRESFL
YRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGAPNK
RSPAASQAPVSRVSLQVCDHRRLTKCRESKRC
>A0A6S7A235|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter animicus|TrEMBL
MARIHTLTRRHDAPAMLVQLTDSHLFGEPETSMLGVNTDASLRAVLRQIEADGKHPDLLL
ATGDLSQDGEAAGYQRFARILSESAALDRATIRCLPGNHDQPSVLRQELSDWSMPVTDVG
AWRVVTLDTTVPGSNAGHLCNSELDMLEAALAQAPNRHTLVAMHHNPMQIDSHWHDSMMI
DNPQALFKLLARFPQVRVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHIVDNMA
PGYRWIKLYQDGSMATGVRRVQDALWHTALQPPDSARAA
>A0A6S6ZRW0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter animicus|TrEMBL
MTRILHLSDTHFGTERKAVVEAVLDLARQLSPDLVVLSGDITQRARRSQFAAARRFIERL
ALPVLAVPGNHDIPLYNVFARALNPYGNYKRALGPILEPVFENDGVLAIGVNTTRPKRHK
DGEISDAQIARVAQRLRQARPGQLRLVVAHHPVRAKVESDLSNLLIGRERALSAWAQAGV
DLVLGGHIHLPYVLPLTAPTGPAGWIVQAGTTCSHRVRGTVPNSLGVITRSEEEGQQVCH
VERWDYAAGAHAFAPVDKTLVSL
>A0A2P8ASB5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micromonospora sp. MH33|TrEMBL
MDGQENEQHGTGDETAPEDRRARRRWRPGTWLRRLGVVLALLVVTLAGVVAGTYAGGHVG
TDIGPFRAQLNLSPSLSGGTTVDIPPLGALLLDSHDGPAYLTVELGALDQRRTEALIDDP
ASISRASQSAVEDVRAGVMRLGLKTLASAVLATLLLAGLVFRDARRTAWAGGLALAVTAG
SLGLAAATIRPQAIEEPRYEGLLVNAPAIVGDARRIANDYTKYAEQLQRLVGNVSKLYTT
VSALPVVQPSPGTTRVLHVSDMHLNPTGWQLIRTVVEQFNIDVVIDTGDITDWGSEPEAS
FVGSIGLLKKPYVYIRGNHDSAKTAAAVAAQPNAVVLDNSTTTVAGLTIAGIGDPRFTPD
KETSPAGSGLTKVVADQVIGAGEQLAATVKASPKPVNIALVHDPASAGPLSGTCPLVLAG
HTHARQVSKLPQVPDKQPTQLLVEGSTGGAGLRGLEGEKPTPLSMSVLYFDQQKLLQAYD
DITVGGTGQSQVNLERHVIQDPKKGDQVPVTPTPTRGGPVSPAPNGSPTATPSPTG
>A0A2K5YDM1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mandrillus leucophaeus|TrEMBL
MPLVDFFCETCSKPWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVE
IPSPTMKEREKPQAPRPRPSQPPPPPVPHLQPMSQITGVKKLMHSNSLNNSNIPRFGVKT
DQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYM
LTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDVSDCPVSPSPSVFVTLALMYNDES
VLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMV
ETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRE
RERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYY
SAIRQSPSPPPEEESRGPGHPPPPDKFQFELTLEEEEEEEISMAPIPCTAQEALTAQGLS
VAEEALDTTMAREASPAQESLDVMAQDESLEAELEEVYLTQQAQSTGSAPVAQDEFSSQE
ESVVAVSQSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACS
ACTGTSGEDTSALPAPGGGGSGGDPT
>A0A6S7BIE1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia ultramafica|TrEMBL
MSSDLPSQPSRRSALKCLAFGGAGTLYVLAGGVFTPMDLALAASTEDKSAISGVPLFLQI
SDSHIGFNKEANPDVAGTLKQTIDYVNAMPVKPALAIHTGDITHLSRPEEFDLASQLLSG
LSITELHTVPGEHDVTDGPQGEYFKRFGQQSDNRGYYSFDHSGVHFIALVNVLHFTPNAL
GSLGEDQLAWLEKDLKGRSASTPIVVFTHMPMWTLYAPWGWGTGDAGQAMDYLKRFGSVT
VINGHIHQIVSKVEGNITFHSARSTAYPIPTAGNGPGPMPLTVPRDQLPKMLGVTSIRIL
RHPLAAKLSDTTLA
>A0A853GQB3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alcaligenaceae bacterium|TrEMBL
MQSSFFVVQISDPHLLADAEGCLLGVNTDHSLRGVIDDIKRREPQVDVVLATGDIAQDGS
VQAYERFLHHASAINAPVYGLPGNHDDGDTLRSVWQARLDPVVDLGNWRIVLLDSSVPGS
NSGHLAQSQFDVLQAAATQAHDRHVLVAVHHNPVPMGSPWLDGMTIDNGDALFQMLERLP
NVRCLLWGHIHQEYDDVHQYSPTHGLRLLASPSTCVQFKPYSETFELDTVSPAYRWLRLH
ANGDVETGVQRVEGLGVYPDLGGTRY
>A0A1E5ELL8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio tasmaniensis 1F-187|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDAIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLDKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGNN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWEVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGSVSTQVRRLPHGQFLPDFEAAGY
>A0A0F8AHG6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Larimichthys crocea|TrEMBL
MYRRSPCARGRVHFDFSEEVIRKLHATNHAHAHSFDVENGPSASCSPLDPQASPGSGLVL
HTNFPGHNQRRESFLYRSDSDYDLSPKSMSRNSSIASELHGDDLIVTPFAQVLASLRSVR
NNFTVLTNVQCASSKRSPAATTQPPITRVCLPGTDKYSISTFDKTIKYQTFDSDICRQFF
PHSRQKTVTCCCVKRDQDERQRN
>A0A8B9Z206|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bos mutus grunniens|TrEMBL
MQFLGSPKEGKQRASSSSVPQFPHVSPWGSLSGSRGEGGARAPWVRSPPGPAPMAVQKRS
RAASAASSLHAVLAMQGAPAPAPAPGPSSPRGSPRGSPGLFRKLLVNQRIRLQRRFTVAH
PLCLDLENGLSCGRSILDPQAGSGFGQIVQAPAQHSQRRESFLYRSDSDYELSSKTMSRN
SSVASDLHGEDLIVTPFAQVLASLRTVRSNVAALARLQDRGAAKQACVCNTPSGSQPPPP
KGNVPTPIPSFHCGTAVNFLSVVTSPVHESLSCANSKPSSPKHPWGWREPGVLSGLIGKS
CRVQIQRRGQEGRGVPEWGVGQTPDQLGPQKTLGRSWLWRHWTSWTGVWISWRLCRRGTQ
WGRWPPTSSSGC
>A0A2I3CEI5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio alginolyticus (strain ATCC 17749 / DSM 2171 / NBRC 15630 / NCIMB 1903 / NCTC 12160 / XII-53)|TrEMBL
MQSSSDSIKLLQITDTHLFAADEGGLLSVKTVDSFNAVVADVLRRNVAFDYILATGDISQ
DHSAESYQRFANGIEPLEKDCFWLPGNHDYKPNMGSVLPSPQIKAAEHVLLGEHWQLILL
DSQVVGVPHGRLSDQQLTLLEEKLAEHPERHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVERFDNVKGILCGHVHQDMNVLHKGIRAMATPSTCVQFKPNSDDFALDTTSPGWRELQ
LHACGDITTQVGRLPDGQFQPDFSSNGY
>A0A0S7H1F8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
MIVTPFAQVLASLRTVRSNFALITGQQDRAASKTRSSGSNPPSMCKTSLAEEPHQQLAIE
TLDELDWCLDQLDTLKTRNSVSEMASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLE
KPDDMDIMSPTTKEKDKKKHPMSQISGVKKATHSLVPSTIPRFGVNVSQEEFLAKELEDI
DRWGLDIFKVAEYSGKRPLTVTMYTIFQERDLLKTFKIPADHFINFTMTLEDHYRSDVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLENHHLAVGFKLLQEDNCDILQNLSKKQRQSL
RKMVIDMVLATDMSKHMNLLADLKTMVETKKVTNLGVLLLDNYSDRIQVLQNMVHCADLS
NPTKPLELYRKWTDRIMVEFFTQGDREREKGMEISPMCD
>A0A6G9Q5W4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lentilactobacillus hilgardii|TrEMBL
MIRIAASSDNHLDLNKVPTDGIIHQQAQYLTENKIDYYLVAGDLFNDFHETVSYIQQLSG
QLSITQVLFIAGNHDMIRNVTYDQLENGHWPGYLNNHYFDIPETNYRIIGLNGWYDYSFA
KNTGKTEVQFHQWKMAYWIDSLIKQPMSDPQREGIVIDKLKEQLEMAQKAQKKVILMTHF
VPNQLFIRYTGDNRFWNMANAMLGSVKVGQLIDEYAVPIVIFGHIHDHMNPRKIGNTWYY
NGAVGYHNHHHNEWQTNTFYSEWLKQLKTIQLF
>A0A246NBW9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. VS1|TrEMBL
MDSLLTLPAANGSEIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIAAQQRDYDLII
ATGDLAQDHTVEAYQHFVAGIARLPKPCVWLPGNHDFQPAMVDTLAQAGIAADKHVLLGE
HWQLVLLDSQVFGVPHGMLSDYQLEWLDRTLRQFPDRYTLVLLHHHPLASGCTWLDQHSL
RNPHQLDAVLQNFPLARHLVCGHIHQELDLDWHGRRVLASPSTCVQFKPHCTNFTIDTVA
PGWRWLTLQADGTLHTEVNRLQSDLFRPDLDSEGY
>A0A1S8YSX9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Izhakiella australiensis|TrEMBL
MDSLLKLSAASGASVRILQITDTHLFAGKHETLLGVNTWASYKAVLDAIEVQSTRYDLII
ASGDLAQDHSVEAYQHFVEGIQRLPAPCVWLPGNHDFQPAMFATLAAAKIEQAKQALLGD
SWQLVLLDSQVFGVPYGELSDYQLDWLEKALARYPQRHTLVLLHHHPMASGCTWLDQHSL
RNSHMLDAVLKNYPLAKTVVCGHIHQELDLDWNGRRMLATPSTCVQFKPHCTSFTIDSEP
PGWRWLDLYADGRVETVIERLTTRAFVPDLDSEGY
>A0A4P7NYA8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hydrogenovibrio crunogenus|TrEMBL
MKIAHISDTHGCQPNLLWSPTCSNQAQATGLDLLINKFGDIDVLVHSGDFMAHSLCENEL
KNFIEWFDSLPFKHKILVPGNHDILCEEFQNKPEQRDKFFPKGMHLLINESVEIDGIKFW
GSPYTPWFHDWGFQLHQHEAETLWPKIPDDVDVLITHGPAKGILDDLYAENKEDPRISSV
GCPFLLKRINELDTLKAHLFGHIHGGYGRSEQNGYVALNSAIMNERYAPDNLPQYLEITK
>A0A379VL50|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica I|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPHVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A4V1FG45|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nissabacter sp. SGAir0207|TrEMBL
MESLFTLPVAGDAKVRILQITDTHLFAGEHQTLLGVNTLRSYHAVLDAIAAEQRPVDLIA
ATGDLAQDHSLAAYRHFTAGIHRFQAPCLWLPGNHDFQPAMVDALAEAGIAPSKQALLGD
HWQVVLLDTQVFGVPHGALSEYQLEWLERCLKAYPERHTLLMLHHHPLPSGCTWLDQHSL
RNAHELAALLARYPQVSTLLCGHIHQEMDEEWHGRRLLATPSTCVQFKPHCTNFTIDSVA
PGWRYLDLWPDGRLETEVCRLTTDEFSPDMDSDGY
>A0A2R8CC78|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Falsiruegeria mediterranea M17|TrEMBL
MTEPLFTFAVFTDTHIRAPEGDLSSPYAVNTKANARAEVAAALVAAQNPALTIHLGDMVH
PLPHMAAYEPACQEARRVFACLEPNLHFVPGNHDIGDKPHDASPAGAVTPDAVAAYSGQF
GDQWSHVDHGDCRFVLINSSIVGSGLDVEQEQFDWLEQVLATDKRTFLFSHYPLFIDSVD
EDEHYDNYGLQGRTRLLEVIERHGVEAVLSGHVHQFFYNRAGETKFYCLPATSFTRQDFA
ELYNAGPEAEFGRNDRGKFGIMLVDVFTDGHRLRFVPTGGAESDAVVDMSQRKPPANSGL
VPFMRHAWYQSRDLPYTGAMEEFSRKRARNDYPLLRLWQMGIETVRTPLADLARPESLRR
VQDFAATGIRFHMFTTSMPDERMLELIAANRDALAGLEIVQVEPDLARVKEIAKALMKTV
DVPLYVSRAATSADNAVEGQIYAHNVWTGYRYARRAEILDGLADTGLPLRPIFAVGWRAD
WLGKIGGLQDAFEHRGIEGAVAVQLMTGSPATANFDDDYIVESVAELVRGRARHPRVTVM
LDTFETIDRGYNPRHGLIDRLGNLTPAGRSLTLSRD
>A0A1V2GI48|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGSLTTEVHRLADTHFQPDTASEGY
>A0A657FVI8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Denver|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A3R9DNN7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MHVVQLTDAHLFADPAGTLLGLNTRDSLRHVVSQVRREQPRIDLLLCTGDLSQDASVASY
AAFRELTEGFAVPTRWLPGNHDEARVMARVAPDLVHAVTDIGAWRVVMLNSAVLGATHGL
LEQDQLSTLDNALASVGERHCLVCCHHQPVDIGCAWIAPIGLRNADELLQRLRAYPQVKA
LLWGHIHQEWDEVRDGIRLLATPSTCIQFAARSEDFKVSEEQPGYRWLRLHADGRLETGV
ERARDFVVTLDFNSPGY
>K4W0U3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O111:H11 str. CVM9455|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYRHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A2S5CFQ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylovulum psychrotolerans|TrEMBL
MAALDCDMAIQLDGGIERLVELCNLGFYDEIQQQKPSDAPKDQVTQPGIKENMKMQSPLF
PKPSGDFPTVVEDTKGSTIQNEPASAKWEPVNSSKSSEGLTANNSTSGNDRDGRDGAKER
DESCSLTDSADSREEMVDQQQSVESFFKRFVKMVSSNEKSLNANSEASDDPTAQTDLIGN
PVQSISNNLNYLNPLETTDDMPVPLLDRATDSEQPAFDAFLCHNSSDKSSKSIVWLHLSD
LHLCEPKTGWDANRVLNSLLKDLKNMEQTHGLLPQLLFFTGDAAFGNYGSGKGSSLAEQY
EEVETFLTGVRRAFSQEISKENTFLVPGNHDVDRGEVAESETHWIETQATTDNVTRLIKD
KPRQWRLFMDRLTTYREFLKKNSYSHLLEDPDRLIYSQIREINGIKLGIGGFNSAWNCSR
DKEKSKLWLGADWQDGAIVGNLDKLNADLKIALIHHPPGCFVEQEDALLRRIMETHFDFF
LHGHEHQNWVNAINNQHVRIAAAACYEKSDQENGYNFVRLNLDTGDVEIWLRRYDGHGDG
WIPRAVAGKTKDNGLWLTSIETKLC
>A0A7X9I1K2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia sp|TrEMBL
MESLFKLPLVNGAKVRVLQITDTHLFAGEDETLLGVNTFNSYRAVLDAIKAQQREVDIIA
ATGDLAQDQSVAAYHQFCRGISELPAPCVWLPGNHDFQPAMFETLHDAGINPSKHVLLGD
HWQIILLDTQVFGVPHGELSEYQLEWMERCLKAYPDRYTLLMLHHHPLPSGCTWLDQHSL
RNAHMLANTLVNYPKVNTLLCGHIHQELDLDWYGRRLYATPSTCVQFKPHCTNFTIDTVA
PGWRYLDLYPDGRVETQVFRLESTEFHPDTESDGYE
>A0A554PLD8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. ATCC 13985|TrEMBL
MPSVSTLTTDDPVLLVQLSDSHLFAEADGTLLGMNTRDSLQRVIELVLEQQPRIDLMLAT
GDLSQDGTLESYQLFRDMTRQIPAPARWIPGNHDEPQLMAQAATESSLLAPVVDIGNWRI
TLLDSAVPGSVPGYLQDEQLQLLASALSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPH
ALFAVLERFPQARAVLWGHVHQEIDRQQGSLRLLASPSTCIQFEPGSEDFKVGETAPGYR
WLRLLPDGRLETGVERVTGFDFQVDYGSDGY
>A0A7Y7ZYC7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. IPO3779|TrEMBL
MPSVSALNPDASALLVQLSDSHLFAEADGGLLGMKTRDSLQRVIETVLAQQPQIDLVLAT
GDLSQDGTLESYQAFRDMTRQIHAPARWIPGNHDEPQVMQQAAINSALLEPVVDVGNWRI
TLLDSAVPGSVPGYLQDQQLQLLAQSLSEAPTRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRGVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLDTGVERVQGFVFQVDYGSSGY
>A0A8F6CQ26|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylococcus capsulatus|TrEMBL
MPDSGTLCLLQLTDSHILPDAEGRFYGIDSAASLGAVIDHANRRRFDLVLFTGDLAQEPV
PQSYRRLAGICAALPAPCHWLPGNHDEPALARHVLESTPLLHQPVIRRGRWLIVCLDSTV
PGSAGGSLSTGQFDLLERTLSRHPSLHTLVALHHHPVPSGSAWMDTMILDNAGEFFAVLR
RHPQVKAVVHGHTHQVADVEIEGTRVLGTPSTCIQFRPASQTFALDAERPGYRWLELGPD
GSVATGICRVAVPPASDTA
>A0A226MXV0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Callipepla squamata|TrEMBL
MGALELAVSPVKRLRTQYAFPCLFAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQHEVEIPSPTQKEKEKKKRPMSQI
SGVKKLMHSSSLTNSSIPRFGVKTDQEDVLAKELEDVNKWGLQVFRVAELSGNRPLTVIM
HTVFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALE
AVFTDLEILAAIFASAIHDVDHPGVSNQFLINT
>A0A252F058|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella putrefaciens|TrEMBL
MLKEAVSYSIAEEESVRIVQVTDPHLFADPEAQLLGVNTSKSFAAVLNTIRAVDYPAHLM
LATGDLSQDYSPESYRQFVAAVAPLNLPCHYLPGNHDDPRIMFLHMQGERIFGQQRILVG
KWQILMLDSTVRGKPGGNMAESQFELIEQAIAAHPDRHTLLVMHHNPILVNCAWLDQHCM
DNGTEFLRRVAQYPQVKGLLWGHVHQQLDTDYDGPHGALQLMATPSTCIQFKPQSPYFAL
DGLQPGYRLLELKADGSICTNVYRVPGNLFSPDKDSSGY
>A0A369Z7F3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aggregatibacter aphrophilus|TrEMBL
MLNTYQYNIQQEVFRIVQITDPHLFKDANGELLGINTQASFSQVLTEIQQQQYAYDLVLA
TGDLVQDSSDEGYLHFCESVKALEKMVFWIPGNHDFQPKMFDLLTTDNISAKKHILLGDR
WQILLLDSQISGVPHGQLSEYQLDWLLAKLKEYPQRYSLVVLHHHILSTHSAWLDQHNLR
NAHELAYILAPFSNVKGILHGHIHQQVDGEWHGYKVMATPSTGIQFKPDSNTFALDTVQP
GWREIELHADGHIETRVKRIQHKTFLPNLQEEGY
>A0A6S7DWS4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter dolens|TrEMBL
MLIAQITDLHMRTPGDKAYGIIDPAAFLGPAVRALNALAPRPDCVLITGDLTDLGRPHEY
QALRDQLQALEIPYFLLPGNHDDRAQLRAAFPDHGYLQGQGPFIQYAVETYPLRLLALDT
VVPMKSHGELCDERLGWLAARLAEQPDRPTLVLMHHPPFQTGIEHMDDIGLLAGGPELER
IVARYPRVERVLCGHLHRTIFRRFGGTIASTCPGTAHQLALELGPRPTLQYIMEPPGYQL
HWWHDGALVTHHAVIGEYPGPYPFA
>Q846Z1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio vulnificus|TrEMBL
MQHTSSDTLSENSIKLLQITDTHLFASDEGSLLSVKTLQSFQAVVEQVMARHVEFDYLLA
TGDISQDHSAASYQRFADGIAPLEKACFWLPGNHDYKPNMSSVLPSPQITTPEQVELNAH
WQLILLDSQVVGVPHGRLSDQQLSMLEHHLQASPEKNTLILLHHHPLLVGSAWLDQHTLK
DAEAFWQIVERFPMVKGIVCGHVHQDMNVMHKGIRVMATPSTCVQFKPQSDDFALDTVSP
GWRELTLHANGEITTQVQRLASGSFLPDFTSSGY
>A0A7K0BTT5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinomadura macrotermitis|TrEMBL
MLDRTRKRLTGPRARLGYRVLAVVAVGLLGGLAGLLLGGRVDTPVGPSDVTLSLRPSWTG
GTQVRIPPLGSLRLDTHTGPIALQAQLSELHLGPTRALIEKPAEMDRLTEQVTTELWHGI
VQMMVRAVALALAAAFLAGLTVFRSWRRALLSAGTALAGMLAVSLTAWLTFNANALAEPR
YTGLLANAPQVVGDTRNVVERFTAYRAQLAHLVGNVSRLYAATSTLPAYEPDPSTLRVLH
VSDIHLNPAAWNVIRSVGAQFQVDMIIDTGDLMDHGTRAEDAFAKDISSLKVPYVYIRGN
HDSRGTQAAVARQKNAIVLDDATRAVEGLRIYGVGDPRYTPDKKTRGDDVTVEQMHATGV
GLADRLRASGTAPDVIAVHDPAEAQAFTGRAPLILAGHAHKRDTKLLPTGSRLFVQGSTG
GAGARGLEHEEPTPIELSVLYFSRATHRLQGWDDLRLGGLGLTSAQIERHLEPKPDRPVT
PPEQPGPSPQQQTPSTTPATSASPSRDRPGG
>A0A2I8D556|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sp. ASNIH5|TrEMBL
METELPQAPDGSVRLLQITDTHLFASAEGRLLAVPTAQSLAAVLERVQANEHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHHGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRVASQVWRLPLGQFVPDPNATGY
>A0A3A6RCR6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sinensis|TrEMBL
MKLMSSSPDTNSITLLQITDTHLFEPADGTLLSVNTHDSFRAVVDKIVESGDHFDAIVAT
GDISQDHSAFSYQRFEQGIRPLEKPCFWLPGNHDFKPSMGSVMPSEQIQPHEHVLLGDHW
QMILLDSQVVGVPHGRMSDQQLTLLDNKLSEHSNRNTIVLLHHHPLLVGSAWLDQHTLKD
AENFWNVIEKHNNVSAVLCGHVHQDMQVKRGHTTVIATPSTCVQFKPNSDDFALDNLSPG
WRELTLHSDGTFETQVHRLSDGQFQPDFNSAGY
>A0A7K0CI69|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces smaragdinus|TrEMBL
MVLLAQISDLHLDGGERAHERAARVMDYLRALPLDALLVTGDIADHGAQAEYEEAAELLR
APFPVLTCPGNHDRRAAYRKALLGESPSEEPVNRLHHVAGTAILMADVTVPGRDEGVLSP
ETAAWIGATLDELGGSVPALLAFHQPPVDIHHPVADTMGLQRPRELAAVLASRPEVAAVI
TGHVHSAGASLFAGRPVVTGPGVVNTIRLPWEPGDTFADLAAPPGVAFHVLGDDRRLMTH
FRVVP
>A8APR7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAGQHEYDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVFIGD
QWQILLLDSQVFGVPHGELSDFQLEWLERKLADAPERHTLLLLHHHPLPSGCSWLDQHSL
RNAAELDSVLANYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIG
PGWRTLELYAEGSLETQVHRLPGTQFRPDTASEGY
>A0A8E7RCH9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Stanleyville|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A6G9QHN9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella aestuarii|TrEMBL
MLKSAVNYHFDNNQPVRLIQITDPHLFADPDSKLLGVNTAQSLQAVIDSFLTSSLSADLL
ITSGDISQDYSPKSYSNFVEQIASINLPCHYLPGNHDDPRVMALHMQGEHIFGQQRIIAG
DWQILMLDSTIRSKPGGFMGDHQFTLIDLAIKAEPNKHVLLVMHHNPILMKCTWLDQHCM
ANGDEFIQRMSQYPQVKGLLWGHVHQQVDTIHRGPHGNIALMATPSTCIQFKPLSGHFAL
DGLQPGYRLLELACDGSIQSQVYRVEGDRFSPDNDASGY
>A0A5J6QS71|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas lalkuanensis|TrEMBL
MPNPVLPAADESVLLVQLSDSHLFAEADGKLLGMETRDSLRRVIDQVLQEQSGIDLVLAT
GDLSQDGSVESYETFRELVANIPAPARWFPGNHDEVPVMRDVCAGTSALEPIVDFPHWRV
VLLDSTIAGAVPGHFPAEQLALLEQALEGAGERHVLVSFHHHPVSIGCAWMDPIGIRNPE
SLFAVLDRYPQVRALLWGHVHQEFDQLRNGVRLLASPSTCVQFAPGSEDFCVGNEAPGYR
WLRLGRDGAIETGVSRVTGIAFEVDYSVKGY
>A0A6I9P353|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Notothenia coriiceps|TrEMBL
MRKSRSVLSVSPYNDCKEPPDCCFSESFTSPSYTLGVDLRRGRRRFSGNLQLPPLSWRQG
SRTPDEEIIARPTSLPFGAPPRIDITPVDPECFDVENGPSTSCSPLDPQASPGSGLVLHT
NFPGHNQRRESFLYRSDSDYDLSPKSMSRNSSIASELHGDDLIVTPFAQVLASLRSVRNN
FTVLTNVQCASSKRSPAATQPPITRVCLPDEA
>A0A1S2TLP0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella algae|TrEMBL
MLKEAITYGIPEDKSVRLVQITDPHLFAEPEGQLLGVNTANSLNAVINTIQAVKYPADML
LASGDISQDYSGESYRNFVEAIKPLNLPCHYIPGNHDDPRIMYLHMQGERVYGHRRVLAG
NWQIILLDSTVRGKPGGHMAESEIEIIRSAIAAEPDRHVLLVMHHNPVLVDCTWLDQHCM
DNGAQFLKEMGRYPQIKGMLWGHVHQQLDTEYQGEGHKLSLMATPSTCIQFKPLSSYFAL
DALQPGYRLLELKPDGSMLTNVYRIPGERFAPDAEASGY
>A0A8C6JQL3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Melopsittacus undulatus|TrEMBL
MIHGGKDMRTEYIARKGKKAELSSHVIFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHS
QRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTN
LQDRAPSKRSPMCNQPSINKASLTGKN
>A0A7X6CKE6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcoleus sp. SU_5_6|TrEMBL
MTTVSPLRVAQITDTHLFAELDRDWKGIQTAGTLQAILDRLQQIQPPPDILLLTGDLSQD
ETPESYQHLVSFIAPLGIPAYWIPGNHDNIPIMADILNRPPILPEKSFQLGNWQFLLLSS
VEAGCNSGKLSPESLDWLDSQLQQTGDRPVIIALHHHPLPIECEIMDGMMLHNTDEFFAI
ADRYPQIKIVLCGHIHQEFYQQRNGVSYLGTPSTCLQLLPKSHPIVVDKIPPGFRLLDLA
SDGTWETKVERAIEFDS
>A0A6N3J8C0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. (strain W3-18-1)|TrEMBL
MLKEAVSYSIAEGESVRIVQVTDPHLFADPEAQLLGVNTSKSFAAVLNTIRAVDYPAHIM
LATGDLSQDYSAESYQQFVRAVTPVGLPCHYLPGNHDDPRIMYLHMQGEQIFGQQRILAG
KWQILMLDSTVRGKPGGHMAQSQFELIEQAIAAHPECYTLLVMHHNPILVNCTWLDQHCM
DNGAEFLERVAMYPQVKGLLWGHVHQRIDTHYEGPHGALQLMATPSTCIQFKPLSPYFAL
DGLQPGYRLLELKADGSIGTNVYRVPGNHFFPDNDSSGY
>A0A4S3LX57|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacteriaceae bacterium ML5|TrEMBL
MESLFKLPLVNGAKVRVLQITDTHLFAGEDETLLGVNTFNSYRAVLDAIKAQQREVDIIA
ATGDLAQDQSVAAYQQFCRGISELPAPCVWLPGNHDFQPAMFDTLREAGIIPSKHVLVGE
HWQIILLDTQVFGVPHGELSEYQLEWMERCLQAWPDRYTLLMLHHHPLPSGCTWLDQHSL
RNAHMLANTLVNYPKVNTLLCGHIHQELDLDWYGRRLYATPSTCVQFKPHCTNFTIDTVA
PGWRYLDLYPDGRVETQVFRLESTEFHPDTESDGYE
>A0A2H5ZTJ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR32|TrEMBL
MRIYATADLHGRPDRIRAVREAVDRLRPDVLVLAGDLTHSGRGREALDLLDLPGLVVLAI
PGNMDPSDVDEAMDRSAAHRLRGEVLEHQGVRFAGLGASPCDVLVVHEPPQGVLDRAWNG
SHIGSRAVRDYVERHRPLVVVCGHVHESPGVERLGPTTVVNCTMGNDRYLGALVTWQRPE
PQVELLPR
>A0A411MDF0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas tructae|TrEMBL
MPQPSIPLSDAPVYLVQLTDSHLFADPQGTLLGMNTRDSLQRVIERVRDEQPRIDLVLAT
GDLTQDGSLESYTCFREMTENLGAPARWLAGNHDEPLPMEQAAQGTDLLKPVVDMGNWRI
LMLNSAVPGSVPGLLGDDQLSLLERALREAPERHCLICFHHQPVSINCAWMAPIGLRNAD
VLFALLKGYPQVRALLWGHIHQEWDQIREGVRLLASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGSIDTGVSRVTDFEFTVDYEGDGY
>A0A7L6XQG0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. RHB21-C05|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLKAIHAEGQEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVMIGE
HWQILLLDSQVFGVPHGELSEFQLEWLEQKLAEAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSVLVNFPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIG
PGWRTLELFADGSLHTDVCRLEGTEFRPDTASEGY
>A0A6J5KEU8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia phenoliruptrix|TrEMBL
MLLAQISDLHIKRPGALAYRRVDTAAYLERCVAALNALDPRPDAVIMTGDLVDQGEPQQY
EHLKALLAPLEIPYFLLVGNHDDRAALRAAFPDRAELHGGGEFVHYALDVGPLRLIALDS
MVPGHSAGTLCDARLAWLAAQLDAAGGKPTVVALHHPPFACGIGHMDKLRLDPAAASRLA
ALIACYPNVERVICGHVHRPMFVRFGGTIASAIPAPAHQVALDLRDDAPSAFMMEPPAYA
LHRYEPGVGIVTHHAYVDSAEGPYPFYEPEGALID
>A0A836YZT9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Glaesserella parasuis HPS9|TrEMBL
MDDSYIFPLSSPIIRILQITDSHLFASDTCELLGVNTTQSFQAVLNMIMKESFEYDLILA
TGDLVQDHNREAYHRFAKMVKPLVKPLFWVAGNHDLQPQMRNALSIYSQIKPEKHILVGD
HWQIILLDSHIQDSPKGRLESSELAFLKRKLEVHPERYSLIVLHHNILPTNSAWLDQHSL
SNVNDLLATLKAFPKVKAIVHGHIHQEVDAQWNGYRILSTPSTCIQFKPHCNDFTLDAIP
QGWRELCLNIDGSIDTVVKRLDNNNFLPNFKALGY
>A0A6M1YH39|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chlamydiae bacterium|TrEMBL
MSLLKNTHMRIAHISDLHFAKVTFSPTQFLSKRFLGNLYLLFKRGREFKAHRLTNFAKYL
KEQHVDFVIITGDFSQTARDIEFEMAFDFLDELKAENLPTFCIPGNHDAYTKKAYLSKRF
YDFFDHDFDQKFPFTLKMDGFEIHPLGKHYFWVGIDCAKHTPLHASYGIFDEKLETKLKK
GLSLIPKEKHIIFCNHFPFRQSSAKRSHSLLRAHALESLLKQYPNIQLYLHGHEHKHAIL
DLREENLPICIDSGSASHQMKGSFNLLDLSKNHMTVHSLKANHFLPPNIHWEKFSETQFE
L
>A0A3N1WIM4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia sp. JUb26|TrEMBL
MDSLLKLPVASGSSIRILQITDSHLFAGKHETLLGVNTWASYEAVLEAIAAQRRHYDLIV
ATGDLAQDHTTEAYQHFAEGIARLPAPCVWLPGNHDFQPTMFSTLANASIADEKHVLIGD
RWQVVLLDSQVFGVPHGELSEYQLEWLDKTLAQEPQRHTLVLLHHHPLPSGCSWLDQHSL
RNPHMLDAVLQRYPLAKTLLCGHIHQELDLEWQGRRVLASPSTCVQFKPHCTNFTIDAES
PGWRWLDLFDDGRVETEVCRLTTRIFSPDLDSEGY
>A0A137SFA3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moritella sp. JT01|TrEMBL
MGADISKLTAKHNVINLLQVTDTHLFATAEKDLLGVKTQQSFSHVIDAILQNQQPFDAVL
ATGDISQDNSIASYQYFAQHIKRLDKPCYWLPGNHDNIPLMAGALKSEGVLSDKYKVVGD
WQIILLDSQLTGSPSGYLSPEQLVLLDDRLSLHPDKYALVVLHHNTYPVGCKWLDKHILR
NPEAFLAVLAKHPKARHVLFGHVHQQLDQTYDGIHFMASPSTCFQFKPHCDEFTLDGRAP
GWRYLQLHSDGTINSQVWRLSNHDFNPDLESKGY
>A0A5I2DP43|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Miami|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A452IPH9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gopherus agassizii|TrEMBL
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQ
KDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVKTEKEDHLAKELEDLNKWGLNIF
NVARYSHSRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAAD
VAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDES
VLENHHLAVGFKLLQEEHCDIFQNLSKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMV
ETKKVTSSGVLLLDNYTDRIQVCDCNFP
>A0A8D0HDU2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sphenodon punctatus|TrEMBL
MKEHCSTYSSAGPSCVSDSTMESLQPLKPNYMSMCLLAEESYQKLAMETLEELDWCLDQL
ETIQTYRSVSEMASNKVFRSVSDVNFECCALSLSYAAAKVKQHKFYPIS
>A0A6P4I954|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila kikkawai|TrEMBL
MGCSPSTLPAPNAAGGGGVGGAPGGQGSLPLDATEKDGSRLFCIKLRRSRLRRCSCGGVT
LQVPNDGNGSTAGSGTGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHS
VVRRATGSTGTSGTSSSGGGNSHRHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPN
PQLKALLVFHKADSICEAVTAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDA
RSAKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLA
MCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLNMR
LDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAP
THLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSL
PLEAPITKENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVY
SSRRSSNDSIIRTGSSTRTATIVPAKMKANPIIMELLEESLSWDFDIFKLEEITDYHPLL
YLGMEMFRRFDVFATLNIDENVCKAWLAVMEAHYRKSNTYHNSTHAADVMQATGAFITQL
TNKDMLVMDRMDEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAIT
FKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPREQH
SQTEEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPM
FDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLAD
IMAKQPPVGKMANSK
>A0A5E4L4E1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MASLSILFMGVAQALTNSGGGIEPVAQFHFEGNAEDSSGNGNNGTIIGATFVQGISGQAL
SFDGVNDYVKTNANINTLPLTIEAWVYPRSITGTGVNNKYIIDNDAGHNAHAIGIDDNRF
MIVYHDGGLLSSVELSTNTWYHVAGVWEQGSVKLYVNGTINNSAIFLQGSLNGATSDTTI
GEYRWGQPFPRIFDGLIDEVRIYNRALSADEIKADFEKYTPTLTSITVSPPTAYVVKGKT
QTFVAEPEDQNGNHMNVPVTWSSSDTNIGTIDPGTGVFTAKAAGMTIVKATSGDISGSTS
VIVTPGTPSGFRFVQLTDVHIGPDPSSCNRGNSESKDCLLSLQTSIDKFNIVRDDIIAHK
PDFVLITGDLVEWNSAYQYSVFNTLITKFNESHIDVHIVPGNHDRRGKEHPQNILEIACP
EILKYDCFNDLNNYRNYIGSNDSSGVYKYEDGDYFEAKNGYRFIGLDSGYDTDFVPEIKQ
EPNGSGLSTRQKNFVNNSILDDKTVIFMHHPVIDDMCTDNSCNVIAENRDLLVGLAKDKH
VKLVLTGHTHRSKFFDSNGRVNVNFRVNVTIPVTNINTFIRIIEPPFPARSPLFIQTRSA
TKDTLPGYLIVNIEGTSVSKEKIFLDDVRINGSNVTPVTILYLNSPADLHVYDESGRYTG
LNAVGEIENNIPDSYYFEEYKVGNTTLPAFALLYNTTLNYSYEIVSNFSRDNVTSDQATF
NFTIKQKIQGAITTIKYNNVSINRNSRAYLRINTTQTNYTMQIDLDNDSIIDTTKQPETI
KTDYAPTATIISPANSSTWDQGQPVTFNGSGIDNEDGNLNKLTWFSDRDDVIGSGNFTTA
NFSAGTHNIILLVNDSAGQVNTANIVITVRDTLPPVLNIDYPPENKIFNKQNISISGIAY
DDSGILNVTVNGFQAGQENWNAILSLNEGWNIINVTATDNKGFSTIANQTVYYNSSLASD
TQPPVAITNLTHKTGLDKSGRAWINWTWDNPKDQDFSYVIVYIDNIHMENTSGSYFSIDG
LSKDANYNISILSADIVDNTNYTEVKETVKTPPPDTTPPITTIALSGILGSNDWYISNVQ
INLSADDYELGTGLAATEFSFDNINWSTYTVPFNISNEGITAIFYRSTDNAGNIESTKHK
SIKIDKTPPNISISGVADGSYYNSNVTPVITITDTNLNNQTVALNNAPFTSGNIVSAEGN
YTLVASADDSAGNTTTKIVNFAIDKTPPEAAISFNVSSKDIKVYSNETGGEINYIVLPPK
KNSDDKKSDDDKENGWELGRYTLKDLAGNLLELVLKHKKEGKEAKAIVISMQYNGGSRID
AAKNEMQVEYSIEKNSSLKELEQKIEVEKKFDAEAKYSLKENNTEIKLKLEGQKEQKENR
AGIVIFKLVTNKGGLNLTLKER
>A0A5E4HQ66|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MTVTPILNEPALVVKNTIKVLVIADVHLGIEWELYHKGFSIPSQVEKRTKRICEYLENMK
PDRIVLLGDIKHNVPRTSWQEKKEIPDFLETIAAYAPIDIVPGNHDGDIEELITGNVTVH
DMRGFVLDGAGYFHGHTWPVVELLSAKYVVVSHNHPSVRLTDSLGHTVSEKVWIRTHFIE
KSIRDHYGDIEWTNPEVIIMPAFNELCGGIPFNESIHEDLLGPVFANHAIELENARAFLL
DGTDLGTIGNIKKLGITRRRRKRRK
>E1IKX3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli MS 145-7|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A1T4PAU0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cincinnatiensis DSM 19608|TrEMBL
MNVSPSLDPSENIKLVQITDTHLFAPDDGCLLSVNTADSFRAIVQAINEQQMPFDAILAT
GDISQDHSAESYQRFASGIRELQKPCFWLPGNHDYKPNMGSVMPSEQIHALEHVLLGEHW
QMVLLDSQVVGVPHGRLSDYQLTLLDEKLTQYPDRFTLVLLHHHPLLVGSAWLDQHTLKD
SDAFWNVVSQHQNVRAVLCGHVHQNMDREHQGVRVMATPSTCVQFKPNSDDFALDLCSPG
WRELELHHNGQVTTQVKRLMKGAFVPDFTSTGY
>A0A8I1BHT4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella michiganensis|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFTAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGE
HWQVLLMDSQVFGVPHGELSDFQLEWLEQKLTEVPQRYTLLLLHHHPLPSGCSWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEGY
>H3N2X2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella michiganensis|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIRASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQILLMDSQVFGVPHGELSDFQLEWLEQKLAEVPERYTLLLLHHHPMPSGCSWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLDLHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A5Y1WGE5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPTMYSALQEAGISPAKRVLIGD
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A6G6SKW9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteus vulgaris|TrEMBL
MESQLELSVKHKNTVRILQITDTHLFANVEDTLLGINTYRSYHAVLNAIREQGLEVDLIV
ATGDLVQDQTFEAYQHFADGIATLTPPCVWLPGNHDYQPAMIDALNQAGILSAKQVLIGD
SWQMLLLDSQIQGVPHGELSDCQLDWLTRCLESQKHRDTIILLHHHPMPSGCTWLDQHSL
RNSQELAERLKGHTQVKMMLCGHIHQEMDEMWNGIRMLATPSTCIQFRPHCTNFTLDTVS
PGWRYLEMSLSSDEKGKVETQVYRLSGTEFCPDLDADGY
>Q6DAC2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAIKARQDAFDLIV
ATGDLAQDHTLQAYHHFSRAIAQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSAVLDRYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDNMA
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A8D0FY46|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Strix occidentalis caurina|TrEMBL
NFQNSYVNNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSR
NSSIATCVLSSVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITGKKS
>A0A2S6UUB2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alphaproteobacteria bacterium MarineAlpha3_Bin5|TrEMBL
MIIAQLTDTHILESKTESQSAAEQRISDLKRCILDIKNLPAKPDVVIHTGDIAHTADRKE
YQVALELLKILETPVFVVPGNRDSRSNIRQVFSCSNYITGNRSEPIIYAINNFEVRLIGV
DSISPGSNKGYFCPEHLSTLDRLLSSFPEKPTAIFMHHPPIPIETGETNRVEFITKEAGD
EFVSMILKHKQVIRVFCGHSHRAYLEKVGKIEFSTVPSIASDLRLGKYPERMEGVPVYQI
HEFNPSSNFVSHTRLLV
>A0A7Y6E8P7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. C2B4|TrEMBL
MPSVSTLTAADPALLVQLSDSHLFAEADGTLLGMNTRDSLQKVIEQVRAQQPRIDLILAT
GDLSQDGTLESYQLFRDLTRQLDAPARWIPGNHDEPQIMAEAAVQSALLEPVVDIGNWRI
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQVRAVLWGHVHQEIDQLRNDVRLIASPSTCIQFEPGSDDFKVGEQAPGYR
WLRLLPDGRLETGVERVAGFDFTVDYGSDGY
>E9THA0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli MS 117-3|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A446CRW8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter veterisilvae|TrEMBL
MTRILHLSDTHFGTERKPVVEAALDLARSLAPDLVVLSGDITQRARRGQFAAARKFIERL
SLPVLAVPGNHDIPLFNLFARALNPYGNYKRALGAVLEPVFENDGLLAIGVNTTRPRRRK
DGEISGGQIARVAQRLRQARPGQLRVVVAHHPVRAKVDSDLSNLLIGREHALDAWKQAGV
DLVLGGHIHLPYVLPLDPSAPAGGWIVQAGTACSHRVRGNVPNSVNVIARDGEGGCHVER
WDYAAGTHAFAPVDRTLVAL
>A0A5E7EB45|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADPALLVQISDSHLFAEANTTLLGMNTRDSLQKVIELVQAQQPRIDLILAT
GDLSQDGTLESYQQFRDLTGQLNAPARWIPGNHDEPQIMAQAAVQSALLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPQRHHLVCFHHHPVPIGCAWMEPIGLRNPE
AFFEVLDRFPQVRAVLWGHVHQEIDQLRNGVRLIASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGRLETGVERVIGFDFTVDYGSNGY
>A0A7L4A9V6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Circaetus pectoralis|TrEMBL
FDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSS
LPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNKRSPATSQPPVSRVNLQGMC
MTLIITCKLVCGLACDKAVLIWKSIRKNAIFVYVLFPSQFKRMLNRELTHLSEMSRSGNQ
VSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGV
KTEKEDHLAKELEDLNKWGLNIFNVARYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVT
YMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDH
PGSHICVALLDSELALMYNDESVLENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVI
DMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKS
LELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQHACSCVSQVGFIDYIV
HPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQSPSPPLEERGRDCQSLMEKFQFELT
LEEEDSDGPEKDGESISYFSNTKTLCVADPGEEDPQREANIEIVTEDTSPVDT
>A0A5E7VP03|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MAFNKLAGVVLSVCLLTSVSSAQAVTGIPKHMVFASDTQYPWTDKTDSREPESDSEFDIR
SKWLVDTQLASIADFRNQHGSQAQVPVMINGDITAFGHGWQRSFMKDLLDKHFKGDYLYG
LGNHDYENNVDDCFSNSCAAGSIVEFKEHHEGKVDSFDLKITSGFLSKTYSGSLAYSKNI
GEVHMVQLNNEPTYTTRISHPLNPTTFEINDALDWLETDLRLARASGYAIIINMHKPLKH
KGTRAQQKRFYDMINKYQVTAIFAGHLHTEGGDMYWEGSVPMYLSGSTSQQTYLIASFTE
DRKRLEISLVENNQWQNRKLIDTATVHSIFARRP
>A0A5E7M3T5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MISKKVKRFVLGVCLLSMAPLAYSIEGAPRHMIFASDTQYPWTDKLDRREPESDADFNTR
SKWLVETQFASIADFRKNHAQSHVPLMINGDITAFGHGWQRSYMNSMLKKYFNGDFLYGL
GNHDYENNVDDCFSNNCAAGSIVEFKEHHENKVDNFDLKITGNFLSRLYSGSLAYSKNIG
DVHMVQLNNEPTYATRIAHALNPTTFDITSTLDWLENDLRVARTQGYAIIINMHKPHEMM
GDSEQTRRFYQMIRKYEVTAIFAGHLHDQGGDAYEVNGVPMYLSGATSQQTYLVASFSED
RKQLQINLVTDNQWQSRKLLDTVPVKSIWASRP
>A0A1V2R9S0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium actinidiae|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKARQDAFDLIV
ATGDLAQDHTLQAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALAEAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPYPSGCTWLDQHSL
RNAHNLSAVLDRYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A1R4B8Y3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio palustris|TrEMBL
MGSVGLLLISVNHNNLGLLILNVSPSKDNSSSIHLLQITDTHLFAPNDGCLLGVNTAESF
HAVVEDIVNTQVEFDAILATGDISQDHSHDSYARFVEGIKPLEKSCYWLPGNHDYKPEMF
SVLPTPQVVCQQQVVLNEHWQIVMLDSQVSGVPHGRLNQEQLAVLDKALQQHPDKWSLIV
LHHHPVLAGSQWLDQHTLKDSQDFWDIVQRYDKVQGVMCGHIHQELDVDHHGVRVLATPS
TCVQFKPQSSQFCLDNRSPGWREIELCVDGQIKTQVKRLTHGRFLPDYRASGY
>W1F632|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli ISC7|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A5C5Q6X7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas saxonica|TrEMBL
MPNVSTLTTDDPVLLVQLTDSHLFADTDGALLGLKTAESLQRVIDLVRAEQPRIDLLLAT
GDLTQDSTVEAYQRFRQMTQALAASARWLPGNHDDLAPMAEAAVQSRLLEPVVDIGNWRI
TLLNSSVAGKAHGYLEDDQLQLLAQALSEAPERHHLVCLHHHPVPIGCEWMNGISLHNAT
AFWSVVDRFPQVRVVLWGHVHQAFDQQRNDVRLLATPSTCLQFEPGSKDFKVSNQAPGYR
WLRLLPDGDVQTGISRLADFTFEPDYSANNY
>A0A564V2J1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia fergusonii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A1Y0HPK9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sulfurospirillum sp. SL2-1|TrEMBL
MFRLSFAFAAIAVLSLINFYSYKRFLKRLDLFFKIQDVIKWAMIVITLCEICYFLVLRLD
NLDPILYTLFSAMIGVSFMLFCVALLYDLFHIPYAKIPHDYSRRLFIKMVFDVTMLILAL
SYITKGFLNGMKAPRIKEVDIFIDGLESELSIVQITDVHIGKTLGKSFMDDVVKQVNALD
ADMVVITGDLIDMPVNQIGDKLDSLRAIQSRLGVYYVPGNHEYFYGVHKIMEHVHTLGVH
VLSNRSMVINHTINLAGVMDMSGKRFDFEPPDLKRALLHVKPELPTILLSHQPKIVKEMS
GEKIDLILSGHTHGGQIFPFGLLVLLDQPYLSGLYQHSKHTQVFVSNGAGFWGPAVRIMA
PSEIVKINLKVKKA
>A0A6M1Z038|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Anoxychlamydiales bacterium|TrEMBL
MQIFAISDLHLSISTPEKDMKDFGKTWENYQEKIKSNWEKTVTDNDLVLVPGDICWAIKL
KDALLDLEWIHELPGKKVIIRGNHDYWWPSASKLKEALPPSISFIQNSSLLFGDVSIAGS
RLWDTTEYNFNEYINFVYNPKQRKDLQENIQEDLSEKIFAREIERLKLSLEKLDKNAKTK
IVMTHYPPISADLKDSKVSKLLEKYNVDICIFGHLHNLKREKKMFGEKNNIKYILASADY
INFNPIKIL
>A0A2H5XX68|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR20|TrEMBL
MDAKRWLWFVLTSAIVLFALDVIVLLAWQRFVRRRGWNRWLARVPWIVALIFLVVSPYVS
YQRTSINRLEEGMFLLFAASTLWYLPKIPIAIGVIVASAVKMLRRLVHVIRRWFTQRRPQ
QAHTPDPLRRHALETIAWSSAVVPFGIVGKGFFDTDDLTIYEEEITLRGLPRAFDGIRIV
QLSDIHAGSWRSPEPFRRTRAIVEQLKPDVLVITGDFVNFDPKELELIRADLVRLRADIG
VFASLGNHDHYCSPANHSLLRSMISNSGITLLVNSNVPLRVSGETIYLIGTDNTGLGQNF
ADLPAALVGVEPGATTILLAHDPTFWDKQVRGRAPIDLMLSGHTHGGQVGIHFLGVELSV
AQVVYKQWAGLYRDGEQYLYVNRGLGTVGPPIRIGIPPEITVLTLRSPKPQYG
>A0A0L1L8H4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio lentus|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVNQGFDYEAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVDHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLIEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPNGQFLPDFEAGGY
>A0A7L7IM05|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. RHBSTW-00175|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLGAIHAENRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFNVPCVWLPGNHDFQPAMYSALQEAGISPAKTVIVGD
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLVKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGVLTTEVCRLSGLKFRPDTASEGY
>A0A8B3T781|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp|TrEMBL
MDSLLTLPAANGSEIRILQITDTHLFAGKHESLLGVNTWSSYKAVLDAIIAQHRDYDLII
ATGDLAQDHSIEAYQHFAEGISRLPRPCVWLPGNHDFQPAMFDTLAAAHINAHKQVLVGE
QWQIVLLDSQVSGVPHGMLSDYQLEWLDNALARYPQRHTLVLLHHHPLASGCTWLDQHSL
RNSHQLDAVLQHYPLARTLVCGHIHQELDLEWHGRRVLATPSTCVQFKPHCTSFTIDTVA
PGWRWFTLYPDGGLETEVNRLDTDAFRPDLDSEGY
>A0A4U2A6I1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio lentus|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSHNFDYQAILA
TGDISQDHSAESYQKFESGIQPLAKPCYWLPGNHDFKPNMGSVLPSPQIQCVDHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLSEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHSNVKAVLCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTEVRRLPHGQFLPDFAAGGY
>A0A6S6RLI8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arsenophonus endosymbiont of Bemisia tabaci Q2|TrEMBL
MDSLFKLTTKQKSLVRILQITDTHLFANVDDTLLGVNTFGSFHAVIDAILARNENVDLVV
ATGDLVQDQSASAYKHFAEGIKRLSAPCVWLPGNHDYQPAMVANLAKAVILPSKQVLIND
NWQILMLDSQIQGAVHGKLSKQQLLWMKRCFDAYRERSHLLMLHHHPLPSGCTWLDQHSL
RNSHILADYLNQYQKVKAILCGHIHQEIDEYWQGVRMMATPSTCIQFKPHCTNFTLDTMA
PGWRYLDLSINDNGENVLDTQVFRLDSDKFRPDFDSGGY
>F0JQG7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia fergusonii ECD227|TrEMBL
MESLLTLPLAGEATVRILQITDTHLFAQKHETLLGVNTWESYQAVLEAIHAKQHEYDLIV
ATGDLAQDQTSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
HWQILLLDSQVFGVPHGELSDFQLEWLEKKLADAPQRHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLANFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTQVHRLSDTRFQPDTASEGY
>A0A6E8VRM3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles coluzzii|TrEMBL
MWFTGYCCGVKGARTAAVGRNHSHDHNKDDGEDYHQTVMGCTPSILSNGSNNQQQQQQQQ
SRKDSGLYVGNVTSSGNGSNDTSNAAAAAAGNNNKLSNSSPVNPTMVNAPYPGAASKDGG
TEKESAKKDSIVSISATGHITSFPVVSTTVRRPTAGSGTSSSSGRYGHRKSSLALTPEEE
PLDSCPRLVSDLKFPNLLPPNPVIKILIAFCKNDPVFEALVNASHRLSLEPTFVKSAESA
IDAFQNPSSGGHHIIIVDARYPRTIEAEALGRSIRNSKGSQHTTMVAVVKKSVFEKDDTA
VISLLDVGYNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQALYTALHRSREAVIIT
DDTLRAQYANRASERVLNMKLDEIVGRSLSDLVTADISNILSHTSRYKDYDGYLTTRRKS
QESSQIHVRAVPVSCIGRNPTHLVLILESSSSALVSTNAIGEALQTLPQGKEVPRGSLHS
IRRGSFDVRSIASDGLRRTSLAKLSSLPLEAPITKVLSLLAQVQENCSLDEAKLLDRVME
FLKREGLYSPQMKEIRTEDPVATDLIGALLTQGPTNILSSRRSSNDSIIRGGGRPSTGSI
VFNKTKESSQLSDLLQTALDWDFEIFKLEDLTEKRPLVCLGLELFRRFDVYNTFNCDEMT
FKLWLIEMEKHYHSENTYHNSTHAADVMQATAVYLQQLSNRELKIMDRMDEATALIAAAT
HDIDHPGRSSAFLCNSDNTLALLYNDICVLESHHAATTFRLTLGDDKINIFKHLDRDMYK
LARSIIVDMILATEMTRHFEHLAKFVSVFGTDVESKDPLPPDNDDNQILVRRMLIKCADV
SNPTRPLKFCVEWARRIAEEYFMQTDEEKRKNLPIVMPMFDRTTCSISKSQIGFIEYIIH
DMMDAWNSFIEMPEIIRYMEFNYSQWKLFEEQGINTLSDIKRKQMSLTEDTASSISLEEK
F
>A0A645CV82|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MGGKYEVKNDGTLLVMNAVLDAEKPDLVVFTGDVVVSKNALEGWERVLAPVELRKIPFAV
TFGNHDTEADVPTTDVLAFIAKRPYNVTTNAGGGVEGVGNCVLPVRNEKEDATAWNLFLF
DSHAYTNDSTLGYYDWIKKSQVDWFVAESNRSAAKNKRNVPALAFFHIPVPEYEYVRLQK
NTVGNTSEKVCSPLLNSGLFFAFMQQQNVKATFVGHDHNNDFVGSLAGIKLCYGRKTGFL
SYCILEKGARVIEINENGEMSTHIRTLHGTE
>A0A645EH83|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MLLSIGKPVYHVIGNHDSDEVARSDVMKFLNQDSSYYSFKNGNVKFIVLDTCFIKTDDGY
EPYYKRNYNKTKDTYPVLPKEQLKWLENELTDNSDYYVIFSHHSLENEFAKRGVHNRAEV
TALINRINNTGRKVLLCINGHDHGDSLEKFGQTYYFGLNSMSYIWVGPEHEHFSYSDEIH
RQYPFIKDLVLYKDELYAIITITEKGGINIEGTNGHYKNVSPGELGLGNRWNGRSVLPIV
TSLKID
>A0A2H5YP34|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR26|TrEMBL
MLIAVIADIHGNAVALERVLADLEREEPDQLVCLGDVAATGPQPREAIVLLRATGCPVVM
GNADEWLLAPRFSASPDESTARIEEIDTWCREQLGPADLAYLRGFRPPIEIALDERTTLL
CCHGSPRSNTEAIRATTPDTELDAMLDGVQATIVACGHTHEQMLRCFGELILFNPGSVGL
PFQVDRRTGTVRNPAWAEYALVRWQSGALGVELRRVPFDARAVVEAASASGMPHAEWWTA
DWAIL
>A0A484BRZ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila navojoa|TrEMBL
MDLKYPTVLPPNPQLKALLVFHKSDSICEVVTLACQRHQLDVTLVKSKEEALETLHKSYA
TAQCYHLIIIDARSTKGLDAEHIASFFEKDDALIALLDAGVNRCIAETTNLTLCSVELKQ
ILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLNMRLDEIISKP
LGDIFVSDLSTISEQGKSIKEFDGILMVRRKNQESIPMHVRVVPVACIGSAPTHLIFNFD
IPGGGMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITK
ENCSADEARLIDKVLDFLKREGLYSPQMKELRTDDPIATDLIGALLTGPSVYSSRRSSND
SIIRTGNSTRAATIVPAKMKQANPIIMELLEESLKWDFDIFKLEEITDYHPLLYLGMEMF
RRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADVMQATGAFITQLASKDMVM
DRMDEATALIAAAAHDVDHPGRSSAFLCNSNNPLAILYNDLTVLESHHAAITFKLTLGDD
KFNIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGSEVEPRELVQSEEETS
ILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRATCSI
PKSQIGFIEYIIQDMMHAWDGFIDMPELITCMQINYSQWKKYDEQGINTLADIMAKQPPV
GNKSSSSK
>A0A6A7Z288|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas helleri|TrEMBL
MPNVSTLTTLDPVLLVQLTDSHLFADADGSLLGLKTAESLQRVIDLVRAEQPVVDLLLAT
GDLTQDATVEAYQRFRQMTDVLAAPARWLPGNHDDLIPMAEAAVQSRLLEPVVDIGNWRI
TLLNSSVAGKAHGYLEDDQLQRLAQALSEAPERHHLVCLHHHPVPIGCEWMNAISLHNAT
AFWTVVDRFPQVRAVLWGHVHQTFDQERNGVRLLATPSTCLQFEPGSTDFKVSTQAPGYR
WLRLLPDGDVQTGISRLADFTFKPDYSANNY
>A0A8C3TAB5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chelydra serpentina|TrEMBL
MTAKDSSRELAAPESDIYIKTFKEQMHLELELPKLPGNRPTSPKISPRSSPRNSPCFFRK
LLVNKSIRQRRRFTVAHTCFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFL
YRSDSDYDLSPKTMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTPNK
>A0A2S9UBM8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cronobacter sakazakii|TrEMBL
MESLLNLPVAGGASVRILQITDTHLFAGKNDTLLGVNTWESYQAVLAELHAEQRECDLIV
ATGDLAQDHTPEAYEHFATGIASLPAPCVWLPGNHDFQPAMYSTLQDAGISPAKRVFAGD
NWQVLLLDSQVFGVPHGELSDYQLEWLERMLQAAPERHTLLLLHHHPLPSGCGWLDQHSL
RNAQALDDVLNHYPQVKHLLCGHIHQELDLDWNGRRLMATPSTCVQFKPHCAGFTLDTVA
PGWRWLNLHPDGSLTTEVCRLEGAQFRPDTASEGY
>A0A095FYJ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Burkholderia gladioli|TrEMBL
MLLAQISDLHIKRPGALAYRRVDTAASLARTVARLNALVPRPDAVLVTGDLTDFGHDDEY
QHLKRLLAPLEIPYYLLIGNHDERGALRRVFAERAELQGGEFVQYALDLGPLRVIALDSQ
ITGQSAGTLCQARLDWLARELEAAAGRPTVVALHHPPFASGIAHMDRQRLDPEAARRLDA
LLRAHPNVERVLCGHVHRTMFARFGGTIALAVPAPAHQVAFDLRPDGPSAFAIEPPAFAV
HRYDPVEGLATHHVYVDDSDGPHPFYDASGALID
>A0A1A0DLI0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lactiplantibacillus plantarum|TrEMBL
MMRSQATYLLQNGVQIYLIAGDLFNDFQRSQQFVVDLQALLGAQTRVYWIAGNHDMVHGI
SFDELETGHFDGYLHNRYIDISGTDWRVIGHNGWYDYQYAAQVPDTTAADFLHWKNAFWI
DRAIKQPMSDQERTDLMLNQVKAQLNLAAVDHKQVIFMTHFVPRIDYLRFSDDNRFWNMA
NALMGTPRLGQLLEQFNVAHVLFGHLHVHPQPRVFGQTTYYDQAVGYGLKRINEWQANNF
MAEWYQDTQILDLK
>A0A6C7HSX7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enteritidis PT4 (strain P125109)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A263HB84|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinobacillus seminis|TrEMBL
MFNTYVYSTEEPVIRLVQVTDTHLFKDINGELLGINTQASFNQVLSEIKQSNFNYDLVIA
TGDLVQDSSDEGYFHFCESVKQLGKMVFWIPGNHDFQPKMFDILNREQENICSKKHILLG
KHWQILMLDSQVYGVSYGQLGQYQMDWLLAKLKEYPERYSLVVLHHHILSTNSAWLDQHN
LRNSYDLAYALSPFNNVKGILYGHIHQEVEGEWNGYKVMATPSTCIQFKPDSNNFALDIL
QPGWREISLHSDGKIVSQVKRIQNATFLPNMLSEGY
>A0A419IP69|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Schwarzengrund|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A174WBW4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Phocaeicola vulgatus|TrEMBL
MTNKLLFFVLLALCFSGCDMLETHPYDVHITGERELTNKNIQLIENKMQGKKTIRFAMIS
DTQRWYNSTEDVVKALNARGDIDFVIHGGDQSDFGVTKEFIWMRDIFNKFQMPYVCLLGN
HDCLGTGEDAYRAIYGDPNFAFTAGNVRFICLNTNAMEYDYSEPVPDFNFIENELNNLSP
EIEKTVFAMHVKPFEFVFNNNVAKIFQLYVNQFPKVQFCLYGHEHKFAVDDLFNDGVLYF
QCPCIDKRIYLLFTIKEDGTYDYETVEF
>A0A8D8J483|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Culex pipiens|TrEMBL
MWLNGLCCGGGLCGIGDVLKDHHHQQHQQHEEDGGPGDCGLAAALRGCPGGRCSTCTVMG
CTPSILSNSSGGSTSNGQQNRKDSGGIYGGIPASAAVTTTTTTSAATTGNDCIKKDSIVS
ITGLGPVSVVSSVLRRPTIGSGTSSSSGRHGPRQTSSLALTPEEEPLDSYPRLISDLKFP
NLWPPNPPIKILIAFCKNDPVFEALVTASHRLNFEPTFVKSHEAAIEAFQNVATGGHHII
VVDARHPRIIEADALGRSIRNSKGSQHTTMVAVVKKSVFEKDDTAVISLLDVGFNRCIIE
SPHVSICSSELRQIQHSLVRPQNVISTQQALYTALHRSREAIIITDDSLRAQYANRASER
ILNMKLDEIVGRSLSELVTADVSNILSQTSRHKDYEGFISTRRKSQETLHIHVRAVPVSC
IGRSPTHLVLILESPASGTTLSALASDALQTLPQGKEVARGSLHSIRRGSFDVRSIASDG
LRRTSLAKLSQLPLEAPITKVLSLLAQVQENCSQDESKLLDRVMEFLKREGLYSPQMKEI
RTEDPVATDLIGALLTQGPTNTISSRRSSNDSIIRGGGRPSTGSIVFTKTRESTQLNELL
SNALAWDFEIFRLEELTERHPLVCLGLELFRRFDVYNTFCCDENTFERWLHKMEEHYCSK
NTYHNSTHAADVMQATACYLQQLSNRELKVMDRMDEATALIAAATHDIEHPGRSSAFLCN
SDDRLALLYNDICVLESHHAATTFQLTLGDDKINIFKHLDRESYKLARSVIIDMILATEM
TRHFEHLAKFVSVFGTDVDAGKETTHDNEDNQILVRRMLIKCADVSNPTRPLKFCVEWAR
RIAEEYFTQTDEEKRKNLPIVMPMFDRTTCSISKSQIGFIEYIIHDMMDAWNSFIEMPEI
VRYMEHNYSKWKLFEEQGINTLNDIKRKQFTLNSSEAAGTTSSVEEL
>A0A661FDX5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MAVSQEKHSGEGFSKDNNGLNIVQLTDLHLFADPESRLLGIQTEESFLSVLELAQKQHAK
PDLMLFTGDLTQDASAAAYQRLQDYLSKLDIPCYCLPGNHDDPELMRSLLNFNNIKTSSS
ILQKKWQIICLNSKLPGSEGGHLAAKELKLLKQSLKSHPDKPTLIVLHHPPLPVGSPWLD
TMTLDNPDALFEIIHQNPQVKGLLVGHVHQDQDWQQNGVRLLTTPSTCFQFKPNSRDFAL
DQQPPGYRWLSLHQNGSIETGISRLASMPEGLNNGSLGY
>A0A0J2HI93|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella michiganensis|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFTAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQVLLMDSQVFGVPHGELSDFQLEWLEQKLTEVPQRYTLLLLHHHPMPSGCSWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A5B0SYF2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter portucalensis|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRARYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A523LB56|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MAQSNTKLPVVLLQITDPHLHAAADSRMRGVRTYETLLAVLDNAKNHTRWPPDAIIVTGD
IVQDESRVGYERFRETMEPFGIPVFCMPGNHDDPQLMAEVLAEYPFQVCGDTTIKGWTLV
FLNTFVSGDDGGTLGATALAALDETLAACSKHHALICMHHQPLPMGSAWLDGVGLRDAER
FLVCIARHDHIRGVLWGHVHQASDRVRDGVRFLSTPSTCSQFLPDSEFFALDNLPPGSRW
LTLEADGRIDTQVEWLQDADLP
>A0A4P7B6L2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter haemolyticus|TrEMBL
MTYQVSTSSQQDFVMIQITDTHLLEYPHLEFVGMQPEQSFHAVIDLMRQQHPQIDLIVHT
GDLAQTPTPVTYNRYIQHMQSLEIPFFHTPGNHDDVAHFPFHEVDQTQLTVIELGKWVII
LLNSAQPQRIDGRITESQLKQLHTLLLKLHDRYVILACHHHPFAMQSAWIDQHKLKNASD
LLETVKPFSNIKAIVCGHVHQDAIHQWQGIEFLSTPSTCIQFKPKSEKFALDEEHPGYRY
ICLKANGELETQVYRLKTSERMSSSEVLGYD
>A0A5H6FDD9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Alachua|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A8D8SNN9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cacopsylla melanoneura|TrEMBL
MWEWCVGTAKCRRHSEKTRTDSLCSQVAENGIHNDILRLPVPPHSTIRILVATSKDDPLY
RDIHSTCESLGYLCQLVTSLDQCVSTCCSYLPHVVLVDLRCKSFRGDQICRAIRSMKRSQ
HVILVALRKKPSLLDKSDDKEIRNILKMGFNKILYEHSSSGGACLNWSVELQSIEQNDVY
LRNLVAHNETAFCALDKSRDLVYITNQAHSIQYVNKACCSVLGYSQDELLHKFIANFHQL
GQMDQIIRQLDRGFDWEGKVSWKCKNGDTIPLHCKAQPFCAFGRDPTHFVYIQENPLDFH
NLPRGSVPSIRKGSYDLKSINSEGAQSARRQSLAKLHNLPLEAPITKVISLISAAQEHSS
DHVINILDKVIDILRTTELYSSHVKAENLRCEDPVTSDLIGALISQGPVHVSSTRRSSND
SANVKSSHPPHTHPHGGATSHTMLNMVTSPQMKELLTTSLSWDFNIFQLEHLSNKRPLVH
LGMNLLVTHYAVHKTLGIDERTLYNWLHLIEKNYHSSNTYHNSTHASDVLQAVAAFLEKE
KLNQILDELDEACCLIAAIVHDIDHPGKSSAFLCNAGNDLAILYNDISVLESHHSALTFK
LTLKDDRANIFKGLERDTYKVARQSIVDMVLATEMTKHFEHLAKFVSVFNTPTVQCHGEQ
AQDYGAQDGSNNKSPSSDPGPDDDYHVNSPEAVNLVRRMLIKCADVANPTRPLPLCVEWG
RRIAEEYFAQTDEEKALKLPVVMPMFDRVSCSIPKSQMGFVDFIINDMFEAWDAFIDMPE
MLYHLRSNYQYWKDMDEKDISSIQDIYPATGPAELIIKSPSHTQQTNKPTSSTQSNNNNN
SVAKPNNNTLSSVAKPNISTISSVSSLSMSNNMNCLPDILETKGDAAD
>A0A8D8YSX9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cacopsylla melanoneura|TrEMBL
MWEWCVGTAKCRRHSEKTRTDSLCSQVAENGIHNDILRLPVPPHSTIRILVATSKDDPLY
RDIHSTCESLGYLCQLVTSLDQCVSTCCSYLPHVVLVDLRCKSFRGDQICRAIRSMKRSQ
HVILVALRKKPSLLDKSDDKEIRNILKMGFNKILYEHSSSGGACLNWSVELQSIEQNDVY
LRNLVAHNETAFCALDKSRDLVYITNQAHSIQYVNKACCSVLGYSQDELLHKFIANFHQL
GQMDQIIRQLDRGFDWEGKVSWKCKNGDTIPLHCKAQPFCAFGRDPTHFVYIQENPLDFH
NLPRGSVPSIRKGSYDLKSINSEGAQSARRQSLAKLHNLPLEAPITKVISLISAAQEHSS
DHVINILDKVIDILRTTELYSSHVKAENLRCEDPVTSDLIGALISQGPVHVSSTRRSSND
SANVKSSHPPHTHPHGGATSHTMLNMVTSPQMKELLTTSLSWDFNIFQLEHLSNKRPLVH
LGMNLLVTHYAVHKTLGIDERTLYNWLHLIEKNYHSSNTYHNSTHASDVLQAVAAFLEKE
KLNQILDELDEACCLIAAIVHDIDHPGKSSAFLCNAGNDLAILYNDISVLESHHSALTFK
LTLKDDRANIFKGLERDTYKVARQSIVDMVLATEMTKHFEHLAKFVSVFNTPTVQCHGEQ
AQDYGAQDGSNNKSPSSDPGPDDDYHVNSPEAVNLVRRMLIKCADVANPTRPLPLCVEWG
RRIAEEYFAQTDEEKALKLPVVMPMFDRVSCSIPKSQMGFVDFIINDMFEAWDAFIDMPE
MLYHLRSNYQYWKDMDEKDISSIQDIYPATGPAELIIKSPSHTQQTNKPTSSTPSNNNSG
AKPNNNTLSSVAKPNISTISSVGKPANVGASSSSVAKSSVLVKGVASVSSLSMSNNMNCL
PDILETKGDAAD
>A0A5J1QSX8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella muenster|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A0J6HDB7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas lini|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEADGTLLGMNTRDSLQQVIELVKLQQPQIDLIIAS
GDLSQDGTLESYQLFRDLTRQIDAPARWIPGNHDEPRIMAEAAVQSALLESVVDIGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPQRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDQERNGVRLIASPSTCIQFEPGSDDFKVSEQAPGYR
WLRLLPDGRLETGVERVTGFDFQIDYGSNGY
>A0A0R9PXL6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella newport|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A827L156|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILMLDSQVFGVPHGELSEFQLDWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A5U2T551|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADVPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A084VQY3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles sinensis|TrEMBL
MDPRSDQPSLSGLRDDDAVRNIAVATDFPPDSQTHPIRGGTSSSSGRYGHRKSSLALTPE
EEPLDSCPRLVSDLKFPNLLPPNPAIKILIAFCKNDPVFEALGNASHRLNLEPTFVKSAE
AAIEAFQSPNTGGHHIVIVDARYPKTIEAEALGRSIRNSKGSQHTTMVAVVKKSVFEKDD
TAVISLLDVGYNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQALYTALHRSREAVI
ITDDTLRAQYANRASERVLNMKMDEIVGRSLSDLVTADISNILSHTSRYKDYDGYLTTRR
KSQESSQIHVRAVPVSCIGRNPTHLVLILESSSSALVSSNAIGEALQTLPQGKEVPRGSL
HSIRRGSFDVRSIASDGLRRTSLAKLSSLPLEAPITKVLSLLAQVQENCSLEEAKLLDRV
MEFLKREGLYSPQMKEIRTEDPVATDLIGALLTQGPTNILSSRRSSNDSIIRGGGRPSTG
SIVFTKTKESSLLSDLLQTALDWDFEIFKLEDLTEKRPLVCLGLELFRRFDVYNTFNCDE
MTFKLWLIEMEKYYHSENTYHNSTHAADVMQATAVYLQQLSNRELKIMDRMDEATALIAA
ATHDIDHPGRSSAFLCNSDNMLALLYNDICVLESHHAATTFRLTLGDDKINIFKHLDRDM
YKLARSIIVDMILATEMTRHFEHLAKFVSVFGTDVESKDPLPPDSDDNQILVRRMLIKCA
DVSNPTRPLKFCVEWARRIAEEYFMQTDEEKRKNLPIVMPMFDRTTCSISKSQIGFIEYI
IHDMMDAWNSFIEMPEIIRYMEFNYSQWKLFEEQGINTLSDIKRKQISLTEEAASSISLE
EKF
>A0A2S2QE64|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sipha flava|TrEMBL
MGYASNSKDVFKYRHESIEKYNIVTLDHRVYSKSADTDEWNVRRPVKNSGTAGNRILIIL
TAMWDNCCRRSGSTSDLSRETVDAYSPINRSDSPLAPQTPENFNYYMFGCSKYIQDLRSN
PMLKKILIVTSKDDSVWQSVTTTARNLDWAVNRVSSSEEALECFHKGNEVPAVAFVDCRH
QNDKTVDAHQIARSLRSIRKNAHVVLVALVRKSFVVRNEKDVTSILTSGFNKIIVETCNK
NVWIKELQQLEKEDISVRSMLIQQDAVLAALDKTKDLVIITDLKHNIQYMNKMGSIVLGY
APEDVVNQPLAVFHQLGDIDQITKKLQKNIEWDGKVSWKCKNGEPVYLQCRAFPFRSFGK
ETTNFIYVQETIAEGHGYPRGSVPSIRKGSYDLKSINSDDFSFKGAQSARRQSLAKLHNL
PLEAPITKVISLICTAQENSNDQVVQILDKVVDILRVTELYSSHLKTENIKFDDPVTSDL
IGALITQGPMHVTSTRRSSNDSATVKNQPYGMGIAKMNFMTSVTPQIKELLDMSLYWDFN
VFKLEELSMKRPLVHLGMNLLMHFEVHKTLGCDERTLHAWLTVIESHYHAKNTYHNSTHA
ADVLQATAMFLEKDRIKRLLDQLDEACCLIAAITHDIDHPGKSSAFLCNSQNDLAILYND
ISVLESHHAALTFKLTTRDERLNIFKGLEKDTYKVVRQNIIDMILATEMTKHFEHLAKFV
SVCNKPSSLDEAPVDGLTPSDVSPETIAPTSAEEVNLVKRMLIKCADVSNPTRPLKMCVE
WAKRIAEEYFNQTDEEKINHLPVVMPMFDRVTCSIPKSQIGFMDYIINDMFETWDSFIDM
PEMLYYMRSNYQYWKDLEEKGTISINEICKTMTTTLPKIPESSGNH
>A0A0Q3MEE9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Amazona aestiva|TrEMBL
MSIVMKPRSRSTSSLRTADTMCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRA
PSKRSPMCNQPSINKASLTEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKHPI
PN
>A0A671S236|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sinocyclocheilus anshuiensis|TrEMBL
CLEPNFLLLHLHLIFFIWGGGMLNRELSHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSP
TLREREKPMSHISGVKKLTHSSSLTSAALPRFGVKTEQEDSLARELNDLNKWGLNIFLVA
EYSNNRPLSCIMFAIFQERDLLKTFRIPVDTFITYVMTLEDHYHANVAYHNSQHAADVTQ
STHVLLSTPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLE
NHHLAVGFKLLHEENCDIFQNLTKRQRQSLRKLVIDMVLATDMSKHMSLLADLKTMVETK
KVTSSGVLMLDHYNDRIQVLRNMVHCADLSNPTKPLAVYRQWTERIMEEFFRQGDKERER
GMEISPMCDKHTASVEKSQVHI
>A0A2K6PT65|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rhinopithecus roxellana|TrEMBL
AFQGSRSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKS
MSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINK
ATITG
>A0A8C0BRB6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Buteo japonicus|TrEMBL
VPGTAGCQAARGGASSAPAPLSPGASPGAGLVLQGTFPHGQRRESFLYRSDSDYDLSPKA
MSRNSSIASDLHGEDMIVTPFAQVLASLRTVRSNLTHLQDRTPR
>A0A2S2CES3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium damselae|TrEMBL
MLTYSLPPRQSDSVVLLQITDTHLFANDAGSLLGVATKDSFHAVLAAIDHQARPFDAIIA
TGDISQDHSTESYQHFAQGIARWQQPCFWLPGNHDYQPSMKAVLPSPQIKPCEQVLLGEH
WQMILLDSQVPGVPHGELRAEQLDMLDRALAAHSERHALVLLHHHPLAAGSAWLDQHQLH
NADDFWQVLARYPAKVKSVLCGHIHQELDCMRQGVRVLATPSTCIQFLPDSDDFALDSKA
PGWRYLELTPQGDVHTQIHRLANDQFAPDLNSAGY
>A0A317ZV93|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. 11986-1-5|TrEMBL
MNVSPSLDPSDNIKLVQITDTHLFAADDGCLLSVNTADSFHAIVQAIIEQKVAFDALLAT
GDISQDHSAESYQRFASEISALEKMCFWLPGNHDYKPNMGSVMPSSQLHAPEHVLLGKHW
QMILLDSQVVGVPHGRLSDYQLNLLDEKLTQHPERYALILLHHHPLLVGSAWLDQHTLKD
SDAFWRVIQQHKNARAVLCGHVHQDMDRIYAGVKVMASPSTCVQFKPNSDDFALDQCSPG
WRELELHADGQVTTQVKRLTRGAFVPDFTSNGY
>A0A8E0IYZ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli HVH 70|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A498QP84|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mycobacterium pseudokansasii|TrEMBL
MVSGLKTSHVFTVPGEHDSVDDAGQNYRSVFGAGTRGGGWYSFDVAGVHVIALVNTLNMN
KLGHLGVEQLEFIERDVARLSSDTPIIVVSHIPLFAMYPDWGWGTDDAAQALHYLRRFSS
VTCLNGHVHQLFPRSKAM
>B7VIX5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio atlanticus (strain LGP32)|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDAIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLDKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGNN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWEVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGSVSTQVRRLPHGQFLPDFEAAGY
>A0A233RJR1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oceanimonas doudoroffii|TrEMBL
MTLSTVPLDTHSRNGVAELSQITDTHLFADREGELLGVATWHSCRAVVNAMKEELAGCDA
ILATGDLSQDQSAESYRHFVAMMSELTPPVFWLPGNHDEAPVMQAELDAAGVSQANHLLG
EHWQVLLLDSQAQGETCGRLSEAQLTLLDTALEHYPQHHLLLAVHHQAVPVGCAWLDQHN
LRNAEQLQVRLARHQANSVVLCGHVHQGFDQVFDGIRYLASPSTCIQFKPLSDDFALDYM
APGWRQLSLYPDGRLSTRVWRLPPNAFVPDFSARGY
>A0A2Z5TFA3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mycobacterium pseudoshottsii JCM 15466|TrEMBL
MAPQVHRLRAAEHPRPDYVLLHISDTHLVGGDDPLYGAVDADSRLAELLEQLKHSGVSPD
AVIFTGDLADTGEAAAYRKLRAVVEPFAAELDAELIWVMGNHDNRAALRTFLLDEAPSMA
PLDRVNMIDGLRIITLDTSVPGHHYGEVRDSQLRWLAEELKTPAPHGTILALHHPPIPSV
LDLAATVELRDQARLGRVLEGSDVRAILAGHLHYSTNATFVGIPVSVASATCYTQDLTVE
VGGTRGRDAAQACNLVHVYPDTVVHSVIPIGTGKTVGTFVSPAQAKRQIAESGMFIEPSR
RDSLFSHPPMVVTPSVRSNPAD
>A0A653VUI4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Frigoribacterium sp. 9N|TrEMBL
MHALPPGALRIVHLSDAHLLADGTLHQGVVDTTEALDLVLAEAARVEGVRLLVGSGDLSD
DGTRASYRHLRERTDAWARAAGAEVVLVPGNHDVREPFAEVLGGDPARPLDLVRDVDGWR
VVGLDTSVPGAGYGLLRPEQLAWLRDELATPAARGTVLVLHHPPIAAPTTLHESLALQDP
EALAAVLEASDVRVVLAGHYHHHIVGHLAGVPVVVAPGVANDTDVLATVGTERAVRGSGF
AVVEVAADGSVRSTVVRAHDPSDGDEVFVLDEAAVARIAAEAGPSPRGRA
>A0A7M1P0U5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus parainfluenzae|TrEMBL
MNNRFEYEPASEIVKLLQITDPHLFKDTSKDLLGINTHESFSQVLKEIQSESFDYDVVLA
TGDLVQDSSDEGYLRFVEMVKPLNKWVFWLPGNHDFQPKMVEHLSQPPINASKHLLLGKH
WQVILLDSQVSGVPHGELSAYQLDWLKTKLAENPARHSLVVLHHHLLPTNSAWLDQHNLR
NAHGFSAVLAQFNNVKGILYGHIHQQVDGYWQGYQTMATPATCIQFKPDSNHFALDTLQP
GWREIELHPDGRIETRVKRIKQKTFLPNMEEEGY
>A0A3B5ACF1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Stegastes partitus|TrEMBL
SFTGSKCCFYFDVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLYRSDSDFDLS
PKAMSRNSSTASDLHGEDMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNKRPTSSNQPS
MCKPCLAGRC
>A0A329VGK5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus laumondii subsp. clarkei|TrEMBL
MESQFELPVVEGTTAKILQITDTHLFASKEDTLLGINTYRSYQAVLDAILKQNADIDLIV
ATGDLVQDQSLEAYRHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGK
HWQLLMLDSQVQGVPHGELSEYQLEWMKNCLDRHPERYAVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQSYSRVKAMLCGHIHQEMDLDWNGIRMMATPSTCLQFKPHCTNFMLDTVA
PGWRYLELSVADNGEFGLTTQVYRLASNEFCPDLDSDGY
>A0A3Q9JMF2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Entomomonas moraniae|TrEMBL
MIAKSKNYSLCIQLTDCHLFADAKKTLLGIPTAESLNSVVAMIQKNHSDIDLVLATGDIS
QDGSLESYELFQEQLNQLATPSLWAAGNHDNFSCVKDRLTFQQYLTKQQNLGEFWRIITL
NSQSIGENCGRISEDELNNLSQSLKDHPDRFHLICLHHPVFSCTNTWLNEIKLQDSWKLL
ERLEGHLNANVILCGHIHQEFEVYYRGTYLFATPSTCIQFAPNSADFKIDTQAPGYRWIK
LFNDGTIDTGISRLDESAYPINLEATRY
>A0A730JZ33|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. houtenae serovar 43:z4,z23:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A2T0BIT5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clostridium vincentii|TrEMBL
MRFIVFGDSKGKENGINKKVLKAILNETCKLNPKPEFIVMSGDTVAGSNKEEILASQLKA
LRNLIYKYHPKMTLIPVIGNHEVNIDPIDDKFEKIFSQNYSDLFPNNSLEGYNNTVYYRD
FGNTRIIVLNAFHYGSTHKIDKDQLNWFEKVASDYKKNKLVFIHSPAFPTGAHLGHCLDL
YPEDRDIFWEIVDKCGIDIVFSGHEHNYSRRLIGKIYQVIAGGGGEKLRNKYNSKKGVVV
APIDVYHFLVVDVEINCIKVTAISSKGKILDEFKIDKTSLSG
>A0A2Z2P098|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Granulosicoccus antarcticus IMCC3135|TrEMBL
MSVTASPARERQLFSKLKWPAAMISLLWLSMIAPPITLAALLSGASFYSFWSISLWVLPA
MFLLLLAVFRTRSRSFRWWVFQYLGVSAVCFTAAACGVILSLFLSNAVAGYWAVFLAILF
CGWAFYSAHRIHTVTLNISNPKIQENLRLVQISDVHIGSRKPVFLEKVIEQVRLQSPDLL
LITGDLVDENVSMADLAPLASMSCPVLYCSGNHERYINYAQVLEDIAAHGVQVLSDQSVE
ILGLRVIGVEDRQQRHEATAALDQLNTFVSSTDTGASIDDTNALPFTVLLYHQPDIWDDA
KRHGIELMLSGHTHKGQIWPFGLLVRTRYAHVAGHFQASLNHLFVSQGTGTWGPLMRFGT
RCEMTVIELQSV
>A0A2Z2NQZ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Granulosicoccus antarcticus IMCC3135|TrEMBL
MKVVHLSDLHIGPGIVMGSNPVEHLRCVLTHVTKFHDDACRYVITGDLVDQGDEQSYRLL
RALLEEFGLTGERAPRLLIGNHDARPQFLSVFPETPCDQNGFVQSVDETPLGWFVYLDTH
QPGTDAGHYCTQRFEWLQGVLDRATAEKQPVWLFMHHNPVPVHVTSSDSIGLVQTAQFKQ
LIARYASTLRHIFFGHCHFTLSGTVQGVPLAAPRSIHESLWPYLEGEQARFATGPLERNY
NVCFIEPDTTIIHTVDYEKYDRIRLL
>A0A8B7LUD2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila elegans|TrEMBL
MDTDTRRYSEPNSNSVAYCPIIGTGTSGTSSSGGGNSRPGHRKSSLALALTPEDEPMDVY
QRNLMDLKYPTVLPPNPPLKALLVFHKSDSICEAITAACQRHQLDVTLVKSKEEALDTLQ
KSYATAQCYHLIIIDARSTKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIAL
LDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLL
RIQYANRATERLLNMRLDEIISKQLEDIFVSDLSTISEQCKNIKEFDGILTVRRKSQEGI
PMHVRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSI
ASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQ
MKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKSNPIIME
LLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYR
KSNTYHNSTHAADVMQATGAFITQLTNKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFL
CNSNDALAVLYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILAT
EMTRHFEHLAKFVSVFGGEEPREHNSQTDEETSILMRRMLIKVADVSNPARPMQFCIEWA
RRIAEEYFMQTDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQ
LITYMQINYSQWKKYDEQGVNTLAEIMAKQPPVGKMANSK
>W0Q8B2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mannheimia varigena USDA-ARS-USMARC-1296|TrEMBL
MVVSSMRECLKIDKRGVIRLLQITDPHLFSNPEDKLLGVDTLASFKEVIQQIKKQIIRAG
DSFDLILATGDLIQDHQIQGYEHFAKITKALNLPIFWLEGNHDSPTEMNEILSAYSHVMP
HKHILVGEHWQILMLNTHVAGQAYGELTESQLNWLESKLAEYPEHFSLIVQHHNILPTNS
AWLDQHSLKNAKELEKVLSKFDKVRAIIHGHIHQQVDAHWQGIPIFATPSTCIQFKPNCD
EFTLDILPQGWREFYLYENGELETVVKRLNSNEFLPNLEAKGY
>A0A5J4RNV4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MLIELNNKKIFAFADTHGKHRQLDVPADADILVCVGDVCNEGNEAQIEDFFAWFAQLPAR
HKLFVPGNHDIPFEIVPHLACTMVPPNVEYVEEGGLMLDDIRFYVLPVRMYMDSPIDIPY
RVDVLVTHGAPWGILGGETYSCPILRDVVDEAQPRIHIFGHIHNYGGQTLQHGKTLFCNV
AVTM
>A0A5J4R372|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MIKIFPIVSALLLILGANFYVFYRLWTMMPVTIAGRILLVTFGVVALSSFVLAQAIGNSL
PLPVTAIMYRVGTSWFFIFVYLLILFLLLEVIRVTGLLPVTGFMYGNWHGLGVLAGALTL
ILTWGYIVYLHKARVELSLIVNKEVSTERSLKIVAISDLHLGYGIRRNEFEKWIELINKE
TPDIVLIAGDAIDSSTRPLYERGIAEAFKQIKTKYGIYASLGNHEYISGISNSLAFLKEA
GITVLRDSVALIDNTFYMVGRDDRTNNARKSVEELTDTLDKSKLLILLDHQPYHLEQAEK
NGIDLQISGHTHHGQIFPLSWITEMIYEKAHGYLKKGDSHIYVSSGLGIWGGKFRIGTRS
EYVVITLQTRKL
>A0A2H5WRK3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR14|TrEMBL
MRYTRREVLKGIGGAVLGLSAMASAKPSNLNRKRVLRIAHLTDIHLQPEGRAVAEFVRCL
KAVHELKPRPDLILNGGDSVMDVFAQNADRARVLGDLWRKTLREHCEIPVEHCIGNHDIW
GWDKNRSGCTGDEPSYGKKWAMELFELSTPYRSFDRAGWHFIVLDATFPAPNSYIARLDD
EQFEWLKEDLKRTPANRPILVLSHQPILSASAYLDGENEKTGNWVVPGQWMCIDARRIIE
LFYQHKNVKLCLSGHIHLYDRVDYNGVTYFCNGAVCGRWWGGNYHQTPPGFAIIDLYDDG
SFEHEYRTY
>A0A090UYX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudescherichia vulneris NBRC 102420|TrEMBL
MESLLNLNLAGEASIRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIRAEQRHCDLIV
ATGDLAQDHSAAAYQHFAEGIASFDVPCVWLPGNHDFQPAMYSALQEAGISGAKRVFAGD
SWQILLLDSQVFGVPHGELSEFQLEWLEKKLAEVPERYTLLLLHHHPLPAGCGWLDQHSL
RNSQELDNVLVRYPRVRHLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELNADGTLHTEVSRLQTSRFRPDTASEGY
>A0A5C2AYB3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cholerae|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFATEEGSLLSVNTADSFAAVVAAIGEEQVEFDAILATG
DISQDHTPESYQRFVRGIQPLQKACYWLPGNHDYKPSMHSVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEHPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRLHLGARVMASPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A544C075|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cholerae|TrEMBL
MKVSSQSEDSSFKLIQITDTHLFAAEDGSLLSVNTADSFAAVVAAIGEEQVEFDAILATG
DISQDHTPESYQRFVRGIQPLKKACYWLPGNHDYKPSMHSVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEYPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRIHLGARVMATPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A428VR97|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas salmonicida|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQVNEHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VMLLDTQVRGKPHGVLGDHQLAALDSALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPGGRVASQVWRLPVGQFVPDPDATGY
>A0A380U4I3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinobacillus lignieresii|TrEMBL
MSSFYSLGKKEPVVRLLQITDPHLFTSESETLLGVNTTDSFQAVLDQIRQSEFEYDLVLA
TGDLIQDHNPEAYHRFAQMVKPLAKPIFWLEGNHDLQPHMGLYLAKYPHISPAKHILAGE
KWQIILLNSQIAGAASGHLSFGQLSWLDKKLAEYPDRYSLVVLHHNILSTRSAWLDQHCL
NNSEQLAEVLRHYPNVRAILHGHIHQEVDDIWQNYRIFATPSTCIQFKPNCDDFTLDLLP
QGWRELNLFDDGHIETQVKRLNSNEFLPDFKSKGY
>A0A0J1HI34|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium ganghwense|TrEMBL
MQKFDLPQKDPDRVVLLQITDTHLFADDGGSLLGVATKDSFHAVLDAVEAAARPFEAIVA
TGDISQDHTEASYQRFCDGIARWPQPCFWLPGNHDYQPSMQSVLPSPQIKSCHQVLAGEH
WQVILLDSQVKGVPHGELSDSQLAMLEQALAAHPQRHALVLLHHHPLPAGSTWLDQHQLH
NADAFWAVLARHPQAKAVLCGHIHQELDCLYQGVRVMATPSTCIQFQPDSHDFALDNNNP
GWRILELLADGQIDTQVYRLTGRQFTPQFDAAGY
>A0A525C901|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MQIIVYNGSVSLLLIQTSKALSVTQERPFRIIQITDPHLLADQKGVFAGLTTQNTFEQVL
KKIKETYFPCDLIIATGDIVHNDAAEQTYKRFADAVSKLGIKTIVTPGNHDDAEILKKTL
RNGLVTADKHYTAGKWQFFLLDSSVKNAVNGHLKEQELTELEELLKKTPEYHTLIAMHHH
PVSVGCRWLDMSGIDNGSRLMDMVEKYPNVKIIMWGHVHQDFVSEKNKVNLVATPSTCIQ
FKPKQVDFCLDRLPPGFRWLDLYNNGHAETGIVRLDELPTEIDFSTSGY
>A0A3R9R1U7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter lactucae|TrEMBL
MTFQVSTLSQKDHVIIQITDTHLLEYPHLEFVGMNPEESFHAIIQQILNKHPEIDAIVHT
GDLAQAPTPITYKRYIQYMQTLGLPFFQTLGNHDNVDHFPLHKENPQEPVVIGLGNWRVI
LLNSAVKGHIDGHLSEEQLEKLTALLEEFADNPILLACHHHPFAMKSKWIDHHKLQNSNA
LLTTLAPFKNVKALICGHVHQDSLNTWQGIEFFSTPSTSVQFKPFSNEFALDQNAPGYRY
IRLKNDGSFETEVFRLENFQGLINTNISGY
>A0A3M1X4H1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MARQVAQARHRTGPANFGKARERGLHSAALPPDCLKVLQVTDTHLYADETGRLLGVNTLD
SFRSIITTFRETGWRPDLVLATGDLVHDASPEGYRRLAHLLDEFGIPVHCLPGNHDIPVV
MREHLRSQRVSCPQVVDCKGWRLILLDSVVPGEVGGHLDAAEIDMLQQALAESDSPTLIS
LHHQPVPVGSDWIDEMGLDNAEALFDSIAGLPQVKGLLWGHVHQLFDEHRNGVRLMGTPS
TCVQFAPGSARFSVDQQQPGFRLLALMPDGQILSEVLRAEGMPQGLDVASGGYE
>A0A2J8V5J6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pongo abelii|TrEMBL
AFQGSRSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKS
MSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINK
ATITG
>A0A2J8T5Z0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pongo abelii|TrEMBL
MTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRESDLSPRPELRKSRLSWPVSSCRRFDL
ENGLSCGRRALDPQSSPGLGRVMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASD
LHGEDMIVTPFAQVLASLRTVRSNVAALARLQCLGAAK
>A0A521XZY3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MNKKAPFRLIQLSDIHLFADAERELLGVKTEESFQAVIDLLHRDEKHIDIILLSGDISQD
NSHEAYVRVARALESFRVPVYCVPGNHDDPRVMAKVYPLATISSERHIVLKNWHIILLNS
HKTNSVEGFFEESELVYLQHCLQKYPEHHAIVMFHHQPFPVGSKWLDNLGLQNADEFWRI
LQQYPQVNTVLFGHVHQEVAKLLHHVKCYAVPSTCIQFKCQDEFSLENIPPGYRWIDLYE
DGHIETAVRRVAEYVGMFDAEAKGY
>A0A1Q5U147|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus thuongxuanensis|TrEMBL
MESLLEVPVAEGATARILQITDTHLFANKRDSLLGVNTYRSYHAVLDMILQQDLDIDLIV
ATGDLVQDQTINAYQHFAKGIARLPAPCVWLPGNHDYQPAMVDTLAAAGISPSKQIFIGQ
HWQLIMLDSQVQGVPHGELTDYQLEWMKKCLDEHSDREAIIMLHHHPIPSGCTWLDQHSL
RNAPELSEYLKGKTQVKAILCGHIHQEVDEIWNGIRVMATPSTCVQFKPHCTNFMLDTVA
PGWRYLELSVAGNNQEAKLQTQVHRLKNNEFCPDLDSDGY
>A0A673LT62|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sinocyclocheilus rhinocerous|TrEMBL
LPSAFKRMLNRELSHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTLREQEKPMSHISG
VKKLTHSSSLTSTALPRFGVKTEQEDALARELNDLNKWGLNIFHVTEYSNNRPLSCMMFA
IFQERDLLKTFRIPVDTFITYVMTLEDHYHANVAYHNSLHAADVTQSTHVLLSTPALDAV
FTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLHEE
NCDIFQNLTKRQRQSLRKLVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLMLDHYN
DRIQVLRNMVHCADLSNPTKPLAVYRQWTERIMEEFFRQGDKERERGMEISPMCDKHTAS
VEKSQVHI
>A0A4W2HRX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bos indicus x Bos taurus|TrEMBL
VFQGRRSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKS
MSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINK
ATLTGKKDLGHYSFHV
>A0A8H1AKW1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. E4694|TrEMBL
MESLLTLPLAGESRVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADSRFQPDTASEGY
>A0A0H3PSS6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O157:H7 (strain EC869)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>E8XBB2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella typhimurium (strain 4/74)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A8E3X9K1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter towneri|TrEMBL
MTLFSNNHQQRWTIVQISDTHLMNQEDLEFVHMNPERSFHAVMHDIQQQYPQVDAIFHTG
DLAQIPVAETYQRYLQFMQTLNTPHFQIPGNHDDAAVFPFHLQSNQVHAIELGNWSVILL
NTAVKGRIDGWMDAAQLQQLDQLLQQHAQQQVIIACHHHPFDIQSHWIDQHKLKNTEALI
DVLARHNNVKLVLCGHVHQDSLNEWQGIQFYSTPSTCVQFKPHSQHFALGPEAPGYRVLH
LNADGSFSTQVHRVEHVTQQINFEISGY
>A0A8C8YK83|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Prolemur simus|TrEMBL
VAVAEVQFGPMRFHQDQLQVLLVFAKEDNQCNGFCRACEKAGFKCTVTREAQAVLACFLD
KHHDIIIIDHRNPRQLDAEALCRSIRSSELSENTVIVGVVRRVDREELSVMPFLAAGFTR
RYIENPSIMACYNELLQLEFGEVRSQLKLRACNSIFTALEKSQEAIEITNEDHIIQYANP
AFETTMGYQAGELIGKELGEMPINEKKADLLDTINSCIKIGKEWQGVYYAKKKNGDNVQQ
NVKIIPVLGQGGKIRHYVSIIRVCSSNNKAEKISECVQSDTNTDNQTGKHKDRRKGSLDV
RAVASRSGETSSQRRHSSMARIHSMTIEAPITKVINIISAAQESSPMPVTEALDRVLEIL
RTTELYSPQFDAKDGDPHASDLVGALVSDGLRRLSGNEYVLSTKSSQQVSSNIITPISLH
DVPPRIARAMENEEYWDFDIFELEAATHNRPLIYLGLKMFARFGICEFLNCSESTLRSWL
QIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPVDKVAALIAATIHDVDHPG
RTSSFLCNAGSELAILYNDIAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQGII
DMVLATEMTKHFEHVNKFVNSINKPLAALEESEETEKNQEAINSMLRTPENRTLIKRMLI
KCADVSNPCRPLESCIEWAARISEEYFSQTDEEKQQDLPVVMPVFDRNTCSIPKSQISFI
DYFITDMFDAWDAFVDLPDLMQHLDNNFKYWKGLDERKFRSLRPPPE
>A0A1M5CMZ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio gazogenes DSM 21264 = NBRC 103151|TrEMBL
MDVSFYTEHLDSIKLLQMTDTHLFASDEGSLLSVNTANSFKAVVQEVIARNVDYQLILAT
GDISQDHSEASYQLFVDSIEPLNKPCLCLPGNHDEQNAMKAILANSQIIQPRHVTVGAHW
QMILLDSQVSGVPYGYISPEQLQQMDDMLRETQARHTLILLHHHPLLVGSRWLDQHTLKN
SDSFWEVVLKYPHVKGVVCGHVHQVMERDYHGVQVMSTPSTCVQFKPHSNEFALDLVSPG
WRELELHPDGQLTTQVGRVKQGLFLPDFSANGY
>A0A6N3QHP8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella flexneri CDC 796-83|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A4D9EWE2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Platysternon megacephalum|TrEMBL
MSIVMKPRSRSTSSLRTADTICFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLPDRA
PNKRSPMCNQPSINKATITGWLQMRTVYPRSSHSPNTRHCVSRRAR
>A0A076LS25|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Edwardsiella anguillarum ET080813|TrEMBL
MESLFHLAVASGAPVRLLQITDTHLFAGQQETLLGVNTYRSYQAVLAAIRAEAHPFDLIV
ATGDLAQDHSAAAYQHFAAGVAALHRPCLWLPGNHDFQPAMVDTLAQAGVHANKRALLGD
RWQIVLLDSQVVGVPHGELSDYQLEWLEQTLASEPQRHTMLLLHHHPLPSGCTWLDQHSL
RNAHALDEILRRYPQVNTLVCGHIHQELDLDWNGCRLLATPSTCVQFKPLCTNFTIDTIS
PGWRYLTLYPDGRVTTAVHRLASSEFRPDLDADGY
>A0A4D9E8I1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Platysternon megacephalum|TrEMBL
MRRSRTALSFLSMERSRDSPELGTCGAAPHMNAIKRRFSGTPLLPPLACRHVVLSEAGRP
PEPEGPRVVFTIEESGPSSGQEPGFLRNAEFLTAPELPGTCRFRGRLPALAAASAPGGRT
APRARAMELSREGAGTAKPPKHLWRQPRTHIRIQQRFHSDTERYLLRRAPDGAPRPGLRQ
PRMSWPCSLQRRFDIENGLSSGRSPLDPQASPGSGLVLQGNVPHSQRRESFLYRSDSDYD
LSPKAMSRNSSIASDLHGEDMIVTPFAQVLASLRTVRSNFAMLTHLQDRVASKRTSSSNP
PSVCKASLSEDACQKLAVETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLS
ETSRSGNQVSEYISSTFLGE
>A0A7G9YU73|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methanosarcinales archaeon ANME-1 ERB6|TrEMBL
MQRSEGGSEDENMKIAHISDIHVVEPHFLPDLAEKVIEKINEIEPEIVVVTGDLTENGYP
FEFERAKSYIERIECKVKVVIPGNHDARNVGDLCFEEIFGPRSKVERYEGITIVGVDSTQ
PDLDDGHVGREKYEWMEKCLDTDGFKVVALHHHLISVPKTGRERQIPIDAGDVLELLIRC
GTDLVLCGHKHVPWIWNLNGMIITNAGTACTNRVKWNIPQSFNLIEIDEEEKGTIKIYRM
YSKGGQEQVLEKRKDKVMRWAL
>A0A6P1ZWH6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nodularia sp.|TrEMBL
MKQVSPISIAQITDTHLFASENHEMLGMPTIQSFQAVVERLKQLRAEVDLLLLTGDLSGD
GKPDSYDNLQNLVNPLQIPAYWLPGNHDCAIAMEDILNMGMLSRRKSFVRGGWNFILLDS
SVPGCLHGYLSGKSLDWLDSELTILGDHPTLVALHHPPFPVNSAWLDSSTLKNPQEFFAV
LDRHPQVRLVLFGHIHQEFQRQRHQVHYLSTPSTGLQFRSKSPTLMIDQQYPGFRLLKLY
PNGMWETSVERVPYFQPLELAAKVS
>A0A1B1KWU5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia inhibens PRI-2C|TrEMBL
MESLFKLTVASGARVRILQITDTHLFAGENETLLGINTYRSYHAVLDAIMAQQRGFDLVV
ATGDLAQDHSLAAYRHFAEGIARLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLLGD
NWQVLLLDSQVFGVPHGELSDYQLEWMERCLQAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHTLGAVLLRYPNVNTVVCGHIHQDLDLEWQGRRLLASPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSEGY
>A0A3R9EEQ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio pectenicida|TrEMBL
MKVTSSSVDGSIKLLQITDTHLFEANDGSLLSVNTADSFDAVVNAIVKQNSNYEAILATG
DISQDHSAASYQRFEKGVSKLNKVCFWLPGNHDYRPSMDSVLSSSRIQYVEHLLLGEHWQ
MIVLDSQVEGVPHGRLSDEQLALLVDKLSCYSQRHTLILLHHHPLLIGSAWLDQHALKDS
ERFWGIVESHSNVKAVLCGHVHQDVDTYRNRVRVMATPSTCVQFKPRSDDFAVDNHSPGW
RELLLCPSGNLTTEVKRLAVGSFMPDFTSSGY
>A0A3A8FDM8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter rongchengensis|TrEMBL
MQSEQSSNPINKDIVFIQITDTHLMDHPDAEFVGIKPEENFHAIMNDIQQRYPNIDLLLH
TGDLAQAAVPATYHRYLAYMQKFAVDFYHIPGNHDDLEIFPFHTPAPHPTVIEVGQWRIV
LLNSVIAGQTDGWIATEQLQHLKHILEQQQDKYVVLACHHHPFDMQSAWLDQHKLKNAEA
FKAILAPFKNIKMVLHGHVHQESLNEWNGIQFISTPATCVQFKPLSQDFAFDAIAPGYRC
LHLKNNGEFDTIVHRLDHFKVTINEEISGY
>A9MPX8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYGALQEAGISPAKHVLIGE
EWQILLLDSQVFGVPHGELSEFQLEWLERKLANAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSLLAHFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A501SBB1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea vagans|TrEMBL
MDSLLTLPAANGSEIRILQITDTHLFAGKHESLLGVNTWSSYDAVLDAIIAQHRDYDLII
ATGDLAQDHSIEAYQHFAEGISRLPRPCVWLPGNHDFQPAMVDTLAAAHINAHKQVLVGE
QWQIVLLDSQVYGVPHGMLSDYQLEWLDNALARFPQRHTLVMLHHHPLASGCTWLDQHSL
RNSHQLDAVLQRYPLARTLVCGHIHQELDMEWHGRRVLATPSTCVQFKPHCTSFAIDTVA
PGWRWFTLHPDGGLETEVNRLDTDAFRPDLDSEGY
>A0A6P4LCP7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila bipectinata|TrEMBL
MRNCLPKFSRVFRRKSSAKSGRENPSNEPDSDGEPYTAVIRPTALSDPPSDNHNESSPSR
LISPANTDLDLDLNLDSGVPAINGGIQGSWPEMKVETISAAAAAEATAAASVPASVAISQ
SFGGRNSGKTPEEMELEYEENVKAEGRDIVTPLRRNTRPLSVAFSGSGRSALQPEIAEVI
RSLDVPALLLNNLSLDTKNRECERETDCYDHEDSCEVVLRRKANCLERKTRSLYERRLPK
VPKLHLQVAGKKTSEEEEFRIFQRNLMDLKYPTVLPPNPQLKALLVFYKADSICEAVSAA
CQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSSKNLDAEHIARTIRHTHGHH
LTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMST
QQALYTALHRLKEVVLITDDVLRIQYANRATERLLNMRLDEIISKPLADIFVSDLSTISE
QGKSIKEFDGILTVRRKNQEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQ
PKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQENCSA
DEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRT
GSSTRTATIVPAKMKANPIIMELLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVF
ATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADVMQATGAFITQLTNRDMMVMDRMEE
ATALIAAAAHDVDHPGRSSAFLCNSNDSLAVLYNDLTVLENHHAAITFKLTLGDDKINIF
KNLDKEQYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGDESRETEEETSILMRRMLIK
VADVSNPARPMQYCIEWARRIAEEYFMQTDEEKQRHMPIVMPMFDRATCSIPKSQIGFIE
YIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGINTLADIMAKQPPVGKLANSK
>A0A5F8GB03|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Monodelphis domestica|TrEMBL
MDRGLTDGNAVDTSDRPGLRKSRMSWPSSFHGTSPRRFRVGNGPSPSPGRSPLDSQASPG
LVLPPSAPHSQRRESFLYRSDSDYDMSPKTMSRNSSIASDLERDFHILTYFFNYSSYALP
QVLASLRSVRSNFSLLANVPAIVGNKKSPMGNQPAVCKATLSGNST
>A0A6I2JZ69|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. CAH-1|TrEMBL
MHADHPRPVHVVQLTDAHLFADPAGSMLGLKTRESLGHVVAQVRREQPLVDLLLCTGDLS
QDASVASYEAFRELTAPFGVPSRWLPGNHDEARIMAEVAPELVQAVTDIGAWRIVMLNTA
VHGATHGLLGDDQLAVLEAALKGAGGRHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDII
GGYPQVRALLWGHVHQEWDEVRDGRRLLATPSTCIQFAARSEDFNVSEEQPGYRWLRLHA
DGRLETGVERAWDFEVKLDFDSPGY
>A0A399DWK6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Meiothermus taiwanensis|TrEMBL
MRVFAIADIHLSKAFPKPMNIFGPEWDGHPEAVFEEWQKVVGEDDLVIVAGDISWAMKLP
EAMLDLADLAKLPGIKVLLRGNHDYWWPSISRLRQVLPPRMHALQHDSLVIGNLAIAGSR
GWDTPGSYNFTPEDEKIYKREIERLGLSLKTLQGHDYQYLVLALHYPPFGPTGGPTGFTE
LIERYRPTCVVYGHLHGADPEKLPKHWNGIPLHFVSADVVRFRPQLILDTPHQTHTHQPT
R
>A0A2K5C6G7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aotus nancymaae|TrEMBL
MQAPVHHSQRRESFLYRSDSDYDLSPKAMSRNSSVASDLHGEDMIVTPFAQVGFGGGVRW
AGQPRLRLLYRRQGPVGNLSSSHQPPPPAEDTGQKLALETLDELDWCLDQLETLQTRHSV
GEMASNKFKRILNRELTHLSETSRSGNQVSEYISQTFLDQQTEVELPTVTTEEPPKPVSQ
ISDLHGLCHSASLSSATVPRFGVQTEQEEQLVKVDQGLVPGSFTHLYTGQWVGLGLIKLH
GNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLLLEGHYHADVAYHNSLHAADVAQSTH
VLLATPALEAVFTDLEILAALFASAIHDVDHPGNHHLAVGFKLLQAENCDIFQNLSTKQR
LSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYPDRIQVLQSLVHCA
DLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIA
HPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSGLTNPERGGPDRFQFGLPLEEA
EEEEEEEEEEGEETALDKEALELSDTELPPEASPDPGDLPLDNQRT
>A0A4S3YP26|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas atacamensis|TrEMBL
MPSVSTITSADPALLVQLSDSHLFAEAHSKLLGMKTRESLQQVIDLVLAQQAQIDLLLAT
GDISQDGTLESYQAFRQMSAQINAPARWIPGNHDEPMVMAEAAVQSTLLESVVDIGNWRV
TMLDSAVPGSVPGYLQDDQLQLLARALSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQVRAVLWGHVHQQIDRERNGVRLMASPSTCIQFEPGSADFKVGEQAPGYR
WLRLFPDGKLETGVERVTDFEFTVDYGSNGY
>A0A6I6ATG6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. MSR2|TrEMBL
MDSLLTLSAASGADIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIEAQQRDYDLII
ATGDLAQDHSVEAYQHFVAGIARLPKPCVWLPGNHDFQPAMVNTLADAGIAADKHVLLGD
HWQLVLLDSQVFGVPHGMLSEYQLEWLEKTLAKFPERHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLQNFPRARNLVCGHIHQELDLDWHGRRVLATPSTCVQFKPHCTNFTIDTVA
PGWRWFTLKSDGTLHTEVNRLQSEEFRPDLDSEGY
>A0A7Z0P6R1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. SbOxS1|TrEMBL
MPSVSTLTSADPALLVQLSDSHLFAEADRTLLGMNTRDSLQKVIELVRVQQPRIDLLLAT
GDLSQDGTLESYQQFRELTRQLDAPARWIPGNHDEPQIMAEAAVQSALLDSVVDIGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQVRAVLWGHVHQEIDQLRNNVRLIASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGRLETGVERVTGFDFQVDYNSDGY
>A0A8C6YHG1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothoprocta perdicaria|TrEMBL
NFQGLASFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKS
MSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINK
ATITGKRDEHDHKFTCESIMGF
>A0A1Q5TMQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus eapokensis|TrEMBL
MESLLEVPVAEGATARILQITDTHLFANKGDSLLGVNTYRSYHAVLDMILQQNRDIDLIV
ATGDLVQDQTINAYQHFAEGIARLPAPCVWLPGNHDYQPAMVDTLAAAGISPSKQIFIGQ
HWQLIMLDSQVQGVPHGELTDYQLEWMKKCLDEHRDRQAIIMLHHHPIPSGCTWLDQHSL
RNAPALSEYLKGKTQVKAILCGHIHQEVDEIWNGIRVMATPSTCVQFKPHCTNFMLDTVA
PGWRYLELSVAGNNQEVELQTQVHRLKNNEFCPDLDSDGY
>A0A6G3L4F5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. V31_P5A7T61|TrEMBL
MNVSPSLDPSDNIKLVQITDTHLFAADDGCLLSVNTADSFHAIVQAIIEQKVAFDALLAT
GDISQDHSAESYQRFASEISALQKACFWLPGNHDYKPNMGSVMPSSQLHAPEHVLLGKHW
QMILLDSQVVGVPHGRLSDYQLNLLDEKLAQHPDRYALILLHHHPLLVGSAWLDQHTLKD
SDAFWSVIQRHQNARAVLCGHVHQDMDRTFAGVKVMASPSTCVQFKPNSDDFALDQCSPG
WRELELHADGQVTTQVKRLARGAFVPDFTSNGY
>W7NUH7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. DC4|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIAIFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLTGAKFRPDTASEGY
>A0A7U8WNQ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cholerae MAK 757|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFAAEDGSLLSVNTADSFAAVVAAIGEEQVEFDAILATG
DISQDHTPESYQRFVRGIQPLKKACYWLPGNHDYKPSMHSVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEYPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRIHLGARVMATPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A2S6U2L4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alphaproteobacteria bacterium MarineAlpha4_Bin1|TrEMBL
MLIAQISDTHILAESSHRPEAGPRAEDLRRCIADINCLDPAPDLVIHTGDTVQTGAPADY
AHLRKLLAPLRMPVYLAPGNRDDRANFRAAFEPAAADGIFLQYTVEEFPVRLVALDSIDP
AHNQGVYCADRQRWLDACLSAAPGRPTILFIHHPPFDVGQHYIDGYRDPADRAALAAIVA
RHRQVRRLLCGHCHRSSQRIWADTQATTMPSVARDLREGIDAQRLAGTPLYQLHALTAR
>A0A7Y4BBH4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio mediterranei|TrEMBL
MKTTPSDESQLSSVRLLQLTDTHLFAPQDGCLLSVNTQESFNAVVAEIVAQGTQFDALLA
TGDISQDHTEASYEKFVAGIEPLALPCYWLPGNHDYKPCMNSVVNSPLIQDVTHVLLGEK
WQVVLLDSQVVGVPHGRLSDSQLEFLDRMLSTHCDRHTLVLLHHHPLLVNSAWLDQHSLK
DADEFWNVVEKHDNVRAVLCGHIHQELDEMRGGVRVLATPSTCVQFKPNSNEFALDVRSP
GWRELELREDGRLHTEVKRLANGSFRPDFNAEGY
>A0A2I0F426|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moritella sp. Urea-trap-13|TrEMBL
MGADISKLTVKHNVINLLQVTDTHLFATAEKDLLGVKTQLSYRHVIDAILQNQQPFDAVL
ATGDISQDNTPASYQYFAQHIKRLNKPCYWLPGNHDNIPLMADALKAEGVLADKYKVVGD
WQIILLDSQLTGSPAGYLAPEQLALLDEQLSRYPDKHALVVLHHNVYAVGCKWLDQHLLR
NADAFLAVLAKHPQAKNVLFGHVHQQLDKTYDGIRFMASPSTCFQFKPHCDEFTLDARAP
GWRYLQLHSDGSVNSQVWRLSNNDFNPDLDSKGY
>A0A833Q5M1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Burkholderia gladioli|TrEMBL
MSIRVRVLSDLHLEGNTPEAVPGAAADLVVLAGDIHNHAEGLRWAAETFDAEVPVIYVPG
NHEYYDGDFGALEAAMRDTARTLDQVHYLNRDVYHAPDGRFRVLGTTLWTDFELYGADQA
RRAEAMTACARAMFDFNGAIQVDWAPGSGASEAGGALATQASRALTPADTLDLHRASRAW
LAAELARPWAGATIVVTHHAPHRDSLAERYANEIVSAGFISDLESLVAPPVDLWIHGHTH
TSFDYTAASGTRVVCNPRGYIRRRTGERENPAFAWDKVVTLEA
>A0A2D4GV68|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micrurus corallinus|TrEMBL
MCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNREL
THLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKLPMSQISGVKKLMHSSSL
TNSSIPKFGVKTDQEDILAKELEDVNKWGLQVFKIAELSGNRPLTVIMYTIFQERDLLKT
FKILPDMLITYLMTLEDHYHADVAYHN
>A0A454A7T8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O6:K15:H31 (strain 536 / UPEC)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A724LNX5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enteritidis PT4 (strain P125109)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5R1QBB6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. BCA17|TrEMBL
MPSVSTVNPDAPALLVQLSDSHLFAEANGTLLGMNTRESLQRVIELVRAQQPQIDLMLAT
GDLSQDGTLESYQQFRDMTRQVDAPARWIPGNHDEPQVMALAAMHSDLLEPVFDIGNWRV
TLLDSAVPGSVPGYLQDRQLQVLAQALSEAPSRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDHERNGVRLLASPSTCIQFAPGSEEFQVSEQAPGYR
WLRLHADGRLETGVERIKGFTFTVDYGSNGY
>A0A7D6J2E9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas chlororaphis subsp. aurantiaca|TrEMBL
MPSVSTLTTDDPVLLVQLSDSHLFAEADGTLLGMNTRDSLQRVIDLVLEQQPRIDLMLAT
GDLSQDGTLESYQLFRDMTRRIPAPARWIPGNHDEPQLMAQAATESSLLAPVVDIGNWRI
ILLDSAVPGSVPGYLQDEQLQLLASALSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPH
ALFAVLERFQQARAVLWGHVHQEIDRQQGALRLLASPSTCIQFEPGSEDFKVGETAPGYR
WLRLLPDGRLETGVERVTGFDFQVDYGSDGY
>A0A263JGU5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gallibacterium anatis|TrEMBL
MSDLFRDESAGVIKLLQVTDPHLFADEDGELLGINTFDSFRQVLSEIKKSGFESNYILAT
GDFVQDNSEAGYHRFVKEIVQLGKKIFWIPGNHDFQPKMEAVFDLYKAVIQPEKHLLLGE
SWQVILLDSQLYGVPHGMLSEEELKWLEQRLSLYPDRNTLIVLHHHLLPTNSAWLDQHNL
RNPYDFSEILAKHKSIKAIVYGHIHQEVNAVWQGIPVFATPSTCIQFKPDCAYFTLDNLQ
PGWREISLYPDGRLETQVHRIKDKVFLPKDNMNGY
>D4BJQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter youngae ATCC 29220|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVCRLQGNRFHPDTASEGY
>C9Y0B6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cronobacter turicensis (strain DSM 18703 / CCUG 55852 / LMG 23827 / z3032)|TrEMBL
MLNLPVAGGASVRILQITDTHLFAGKNETLLGINTWESYQAVLSVLHAEQRECDLIVATG
DLAQDHTPEAYEHFAAGIATLPAPCVWLPGNHDFQPAMFSTLHDSGISPAKRVFAGDRWQ
VLLLDSQVFGVPHGELSDYQLEWLERMLQQAPERHTLLLLHHHPLPSGCGWLDQHSLRNA
QALDDVLNRYPQVKHLLCGHIHQELDLDWNGRRLMATPSTCVQFKPHCAGFTLDTVAPGW
RWLNLHPDGSLTTEVCRLEGAQFRPDTASEGY
>A0A7M2S250|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio diabolicus|TrEMBL
MQSSSDSIKLLQITDTHLFAADEGSLLSVKTADSFNAVVADVLRRNVTFDYILATGDISQ
DHSAESYQRFAEGIEPLEKDCFWLPGNHDYKPNMGSVLPSQQIKAAEHVLLGAHWQLVLL
DSQVVGVPHGRLSDQQLALLEEKLAEHPERHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFDNVKGILCGHVHQDMNVLHNGIRVMATPSTCVQFKPNSDDFALDTTSPGWRELQ
LHACGDITTQVGRLPDGQFQPDFSSNGY
>A0A6A5B8B0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea dispersa 625|TrEMBL
MDSLLTLPAANGSDIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIAAQQRDYDLII
ATGDLAQDHTVEAYQHFVAGIARLPKPCVWLPGNHDFQPAMVDTLAQAGIAADKHVLLGE
HWQLVLLDSQVFGVPHGMLSDYQLEWLDRTLRQFPDRYTLVLLHHHPLASGCTWLDQHSL
RNPHQLDAVLQNFPLARHLVCGHIHQELDLDWHGRRVLASPSTCVQFKPHCTNFTIDTVA
PGWRWLTLQADGTLHTEVNRLQSDLFRPDLDSEGY
>A0A2P7ZB15|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces sp. 111WW2|TrEMBL
MLVLAHISDLHLDGSPRATERAERVRERLWRLPGRVDALLVTGDIADHGTEAEYEEAARV
LGLRDGSAPFPVLTCPGNHDSRAPYRKALLGRPAADGPANEVHVFDGGAVLMCDSSIPGS
DEGELDGETYDWIEASLDGLDDGLPALLAFHHPPTPVHHPLPDSYRLRHPERLAALLERR
PGIAGLITGHAHSPAATVFAGRPLVVGPGVTWTLRLPWEGEQVADRDAPVGLAFHVLDDA
GRLTSHFRTVT
>A0A2U9DY31|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNAFVYQTEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQAVLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLVPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTQVKRIQQAEFFPNMQEEGY
>A0A0Q0I3Z6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. P1-14-1|TrEMBL
MLKQPVSYSIAETDVVRLIQVTDPHLFADPEAKLLGVSTAASFQAVLDTYLASQYSADLV
LATGDISQDYSPQSYQHFSRDIAALNIPCHYLPGNHDDPRLMSLHMQGPHLFGQQRVLAG
NWQILMLDSTVRGKPGGYLAEQEFELIDAAIKAEPNKHVLLVMHHNPILVKCSWLDQHCM
ANGEQFLERMAKYPQVKGLLWGHVHQSIDTEYQGEFGPMQLMATPSTCIQFKPKSSYFAL
DGLQPGYRLLELASNGSIQTQVHRVAGEKFSPDNDASGY
>U6DFT8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Neovison vison|TrEMBL
KFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQI
SGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIM
YAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALD
AVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQ
EEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDN
YTDRIQVLRNMVHCADLSN
>A0A6X7ZMW6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enteritidis|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHYHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A2I2KQG5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Frankia canadensis|TrEMBL
MITLLDPAAHTPSHILIQISDTHIVRPGQLLHGKVDTAATLSTVFGQLEASALKIGAILL
TGDLADTGDLLAYQRLRELVEPAAARMGIPVLYGMGNHDARGPFRAGLFGAEPTTEPHDL
VHWVGDLRVIVMDSTEPGQHGGFLSDAQLRWLADELATPAPAGTVLALHHPPVPSPIAMV
NSLLLAEPEKLAEVIVGSDVKIMVAGHSHHASAGVLGGVPVWVAGASAYRANTLGPADRM
TGLVGGEYTRIDVYPSGAVATSVPIAPSEVLYDLGVDDLARLADEYSAAAGHDAAREHDA
AREHDAATEHDAAVSA
>A0A1B1E9G4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio natriegens|TrEMBL
MQSSSDSIKLLQITDTHLFEADEGSLLSVKTADSFSAVVDEVLRREVGFDYILATGDISQ
DHSAGSYQRFAAGIAPLEKDCFWLPGNHDYKPNMGSVLPSQQIKATEHVLLGDKWQVILL
DSQVVGVPHGRLSDKQLALLEEKLAEYPERYTLVLLHHHPILVGSAWLDQHTLKDAEAFW
QIVERFDGVKGILCGHVHQDMNVLHQGIRVMATPSTCVQFKPNSDDFALDTTSPGWRELE
LHATGEITTQVNRLPEGQFQPDFSSNGY
>A0A2K5YDR0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mandrillus leucophaeus|TrEMBL
MKRSRSALSVAGTGDERPRENPESGHANMLGADLRRPRRRLSSGPGLGWAQPETSDPRVP
LPPRPTTLPLRILPRISIIRAENDRHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPTN
KRSPLGGPTPVCKATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRML
NRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKPQAPRPRPSQPPPPPV
PHLQPMSQITGVKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYA
GGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTH
VLLATPALDSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPPPDKFQFELTLEEEEEEE
ISMAPIPCTAQEALTAQGLSVAEEALDTTMAREASPAQESLDVMAQDESLEAELEEVYLT
QQAQSTGSAPVAQDEFSSQEESVVAVSQSSPSALALQSPLLPAWRTLSVSEHAPGLPGLP
STAAEVEAQREHQAAKRACSACTGTSGEDTSALPAPGGGGSGGDPT
>A0A261QR75|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sodalis-like symbiont of Philaenus spumarius|TrEMBL
MESLLKLPVARGANIRILQITDTHLFAGEDEMLLGVNTFRSYSAVLKAVQAEQRYFDLVV
ATGDLAQDHSPQAYRHFAAGIARLPAPCVWLPGNHDFQPAMVDVLVECGISCAKQVLIGD
EWQLLLLDSQVYGVPHGELSDYQLEWLARALASQPERYTLLLLHHHPFPSGCIWLDQHSL
RNAHMLAEVLQPHQRVKTLLCGHIHQELDVDCLGRRVLATPSTCVQFKPHCTNFTIDTLS
PGWRYLDLLPGGLLQTEVHRLNGTEHQLDTDYEGY
>A0A6N0KSZ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. FDAARGOS_761|TrEMBL
MSRHSNTPATDASVLLVQLSDSHLFAEDGARLLGMDTAHSLEKVVERVAREQPRIDLILA
TGDVSQDGSLDSYTRFRRLSAPLAAPLRWFAGNHDEREPMQRATEGSDLLEQVVDVGNWR
VVLLDSSIPGAVPGYLEDDQLDLLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGY
RWLRLHDDGRLETGISRVDDVVFEVDYDTAGY
>A0A5P1UV16|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. C16S1|TrEMBL
MTYQVSTSSQQDFVMIQITDTHLLEYPHLEFVGMQPEQSFHAVIDLMRQQHPQIDLIVHT
GDLAQTPTPVTYNRYIQHMQSLQIPFFHTPGNHDDAAHFPFHEVDQTQITVVELGKWVII
LLNSAQPQRIDGRITEKQLRQLQTLLTQLHDRYVILACHHHPFAMQSAWIDQHKLKNASD
LLETIQPFSNIKAIVCGHVHQDAIHKWQGIDLLSTPSTCIQFKPRSEKFALDEEHPGYRY
ICLKANGELETKVYRLKTSERMTSSEVLGYD
>A0A8E1V3S6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. 50588862|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAEHRDCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLAKYPRVKHLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLAGAEFRPDTASEGY
>A0A495KU36|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter asburiae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMFSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLTGAKFRPDTASEGY
>A0A8B9MD68|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Accipiter nisus|TrEMBL
APQPLPRDESPRGGGGSIRAPLKDGEDSGGTGQPPLTATAPPGGGRPPRVPPAGEGPRGW
DSGGKCWRVPVPPPSATSVVVLSSPPPSAVVAGGLCGASGVKLGWNWPHPGPHPXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAIPILVPILVPIPVPITVPSPSRPHPHPI
PVPVPFFIPFLSIFVLVPIPVPIQRPCPCPLPHPLLVHLHPCPHPRLHPCPHPHPIPSLS
PSSSPSCPSSPFPSLSPSPSQPCPCPLPHPLLVHLHPCPHPHPHPXXXXXXXXXXXXXXX
XXXXXXXXXPIPVPIPPLSPSPSPSRSPGADRTGVASPAWDPPPPLGVSIPLQGSQPKAW
GEGGSQGWGGGLGGVPEAGGAMRGLSLTPPPCPPQFKRMLNRELTHLSEMSRSGNQVSEY
ISSTFLDKQHEVEIPAPGPKEREKKRRQPPPMGQISGVKKLPPGSGPGSSSVPRFGVKTD
REDLLGKVTGFTGVMGRGGVWEQGGRVVPYPPPRRTPPGARQPQQVGLEHLPRLRVLQQP
LAQLHHVHDIPGAGAGENLQDPGGDVADLHLDLGGPLPRRRRLPQQPARRRRHAVHPRPA
GHPRPRREPPTRRGVGGTCHGVVGPIVGWWDPSWGGGTHGRVVGPMVGWWDHPHGRRRGW
VMGVWYGGECGGAGRLEGVDLGVGGGS
>A0A8F9ZZ23|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gilliamella sp. ESL0441|TrEMBL
MQSFLHLPIKNSDFGNILHITDTHLFANDNNQLLGVDSNASFLSVMDEIKSLKKQYDLIV
ATGDFVQDGSKEAYSLFAKQIQKLNTPCVWLAGNHDNYAYMQIIFKDYQLAENKVVLLGD
NWLLILLNSQVVGQAYGYLSDLELAFLRKTLENYNDRYALVFLHHHAIESGCHWLDQHIL
KNSDQLKNIIQNYPKISGVGWGHIHQNQMHSWYGCKAFSTPSTCVQFKPASYEFNLSLEA
PGWREIKLGKDGEIQTDVFRINSNQFQPDLSQNGY
>A0A2X1N0J5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLLHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A369SG92|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trichoplax sp. H2|TrEMBL
MAEQDSNFIDLLLLGDRIPIGYCRVILAIFSENDKQLNALKQAAEKGNYKLNVVHSERSA
IEYYQDYRPHIVFVDLRSKDAFNGETICKNVKDKSLSNQSTMIAVVNPSNSDKEEPSIAP
LLAMGFNRRFVENFNVGGCLNELIMLEVNDLRQQVKIREADSLFAAIHNAYDSVEITTDR
SQFQYVNPAFERTTGYWSSELIGKLDSVLPISDKNDPELFNTIKSYISRGRTWEGSYVGK
RKSGETYPQFVRVIPIIGHEGFLTHHVTIKRDISEMETKYKKYVEESIKSYPNGKVVDPN
HIKTVEASTSMVINLIKIAQENVSESPNNVTQSLDKVLQILKDAEISFPQGADFDLINFT
ELGNNTITSQGNLPRPSLVVNAKSILNDASAEIKIALDGASDWDYDILELERVTEKRPLV
YLGMKIFERFRMGHYLNASADVLCNWLKLIEANYRQSNSYHNSTHAGDVLHASACFLDCD
RVKNLLDPLDIMASLIAAIVHDVDHPGVTSAFLCNSHNPLALLYNDSAVLESHHAALAFK
LTTSNDKVNIFKGLESDEYRSIRSSIIDMVLATEMTKHFSYLSKFTDCLNSSKNTVIADD
GTELKVIESSSENRMLAKRILIKCADISNPARNWILSKEWALRILDEYMCQYDEEDKEGL
PLTMHMFNREKCNVPQSQRSFYDYFVKDLFKSWHSFAHIPHVMKNIEENYDHWRNVEQKG
IKYFRELNELRNSKDVP
>A0A7W2KWN1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MRRRPVPHPSPSQAPVYVVQLTDPHLFADPAGTLLGLKTRDSLRHVIAQVRREQPRIDLL
LCTGDLSQDGSVASYQAFRALTSEFAAPARWLPGNHDEAKVMAVVAPELVQAVTDIGQWR
VVMLNSAVPGATHGQLEQDQLQLLNDALQSAGERHCLVCCHHQPVDIGCAWIAPIGLRNG
AELLQRLKGYPQVKALLWGHIHQEWDELRDGVRLLATPSTCIQFAARSEDFRVSEEQPGY
RWLRLHPDGRVETGVERARDFEVRLDFDSPGY
>A0A3B3T5I9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paramormyrops kingsleyae|TrEMBL
MDRCSRGDRPGLKKTRMSWPSSFHGTTSTFDVENGLSSVRSPLDSQASPGLVLHPTFPQS
QRRESFLYRSDSDYDTSPKSMSRNSSVTSEGHTEDLIVTPFAQVLASLRTVRSNFTILAN
VTTPTANKRTPMGSTPTVPKATLSGRFNPPYQTLS
>A0A737LLI0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae serovar 42:f,g,t:--|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGD
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQGTRFRPDTASEGY
>A0A2S5B2H4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rhodotorula taiwanensis|TrEMBL
MEQGTRWKRLRLGNQPDKPAFELLVLGCGGGPVGSNLSSYLVKPAAQRWSEGCIGLEAGS
TLGAIVSLAERDSTLFADFFPTHEHDTSMKGERRSDGVDETPQESERDRKARALRTGGVV
WDAITASVTTAPRPVPARRPRSSRQVVLASQEGEGRAFFASEWTPSSRRLIPAFETPVSK
ADTLRLRFFVITHGHLDHIAGLVISSALCRPQVKPIYGVEHTIANIERAMDGGVWPVLGA
REKSKEGKGLAYQYRVIEAPISQSIPLSSALSFSALPVAHGPNPSTSVATPASLASHSKS
DSTKSSSDVYHSTAVFLREEVSKREFLFFGDVEPDSVSGTDLNRKVWTAAASKIVAGSLD
VIFIECSYPSSQPRAQLFGHLSPPYVMEELAVLEELVVASRGTKGGAADAKGGPLAGVTV
VITHIKDELYLPPPDTAPSSATSDPTTSAAAASIEAKYPRERETVHERIERELNELERER
GTGVRFVLAEQGMRLEI
>A0A0J1GFN4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium aphoticum|TrEMBL
MQNYTLPQADPASVVLLQITDTHLFADDSGSLLGVATKDSFHAVLDAIAASACTFDAIVA
TGDISQDHTEASYQRFSEGIARWSQPCFWLPGNHDYQPSMQAVLPSPQIKPCHHVLAGDH
WQIILLDSQVVGVPHGELSDAQLAMLDAALTQHPERHALVLLHHHPLPAGSTWLDQHQLH
NAEAFWQVVGRHPQVRAILCGHIHQELDRIHQGVRVLATPSTCIQFQPDSHDFALDQKSP
GWRLLTLHANGTLETRVQRLDGHCFTPHFDAAGY
>A0A1Z5JY48|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Fistulifera solaris|TrEMBL
MSNTAPPYAATALALSVKHWKDLGIDDGDEETAPTNDLDTLVERLTAILVVRCVAIVAEK
DEFNDLSTATICRSTLMRQAAWPEPITADVVEQIRTFVHAILSRYNDNPYHNRQHAYHVT
TSAHKLLELMLLEKQQTFGLRNDPLMQFALIFAALIHDVEHQGLPNRQLCNEAAKLAVTY
NDQSVAENRSLAIGFHELLKDDYKELRAVLFGNSNEADPSQSDYQRFRRQVISLVLTTDI
ANPERTALFKSKWVEAFESPLVDDDVSVLEDDDEKKDQKEGEDEEDASESRDVVTSDKVG
ERRRSNASTGSLRSRGSSRGGTRLGMRMSIDLSGEALHIYKQVGNSKNSEEPDELKISVL
LELFLTAADVSHNLQGWEQMVKWSNCLYLELQRALLMGRGTDPKPNWFQNQIGFLEFYLL
PLANKLDETGVFGGFVGKQFATTVLANRDRWVKKGQKVTDQIIEEGKKMVIDNATTCNPC
RMDDEADGDLDPESGEMEASNEPGEGGSPTDWVKVFMFVVIVLLLGVILQLSQILRHPRT
SPKGNPGLWKINCRKLGKAVSPMERCKDGYLRIDSGGHATFHVSDNCDDSGMNSCFRNAP
ILTQQDLMKIGLSTVPFEEENLAIA
>A0A653TNS2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Halomonas titanicae|TrEMBL
MADQGLNAQKVPHAQQCLIAQISDPHIKAGGKLSYRQVDTASALRQAISTLNQLAPRPDL
VLISGDLVDFGHPSEYATFKQILAELMLPVYLIPGNHDDREHLRAAFPEHRYLFQHRDYL
HWVVDDYPVRIVGLDSSVPGKPHGELSDESLQWLDTTLAEHPEKPTLVMVHHHPFVSGID
HMDLQPLKRTDALADVIGKHVQVERVLCGHLHRSIQARFANTLAISCPGVSHQVSLDLTP
DGPSSFQLEPPGYLLHQWSATNGMVTHQGFIQRYPGPFPFFDANGLID
>A0A376DMF5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Edwardsiella hoshinae|TrEMBL
MESLFHLAVASGAPVRLLQITDTHLFAGPQETLLGVNTYRSYQAVLAAIRAEAHPFDLIV
ATGDLAQDHSSAAYQHFAEGIATLQKPCLWLPGNHDFQPAMVDTLAQAGVQASKRALLGE
RWQIVLLDSQVVGVPHGELSDYQLEWLEQALASEPQRHTMLLLHHHPLPSGCTWLDQHSL
RNAHALDEIVRRHPQVNTLVCGHIHQELDLDWNGCRLLATPSTCVQFKPLCTNFTIDTIS
PGWRYLDLHPDGRVTTAVHRLAGNEFRPDLDADGY
>A0A837WCI4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas hydrophila|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKSILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRIASQVWRLPVGQFVPDPNATGY
>D0X7A9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio harveyi (strain 1DA3)|TrEMBL
MQSSSDSIKLLQITDTHLFDADEGSLLSVRTADSFAAVIQEVLHRQVQFEYVLATGDISQ
DHSAESYQRFAEGIAPLKKDCFWLPGNHDYKPNMGSVLPSPQIQAVEHLMLGEHWQLILL
DSQVVGVPHGRLSDQQLSLLEEKLAENPQRHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFENVKGILCGHVHQDMNVLYNGIRVMATPSTCVQFKPNSDDFALDTESPGWRELE
LHSNGDITTEVNRLPDGQFQPDFTSNGY
>D7HEK0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cholerae RC385|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFAAEDGSLLSVNTADSFAAVVAAIGEEQVEFDAILATG
DISQDHTPESYQRFVHGIQPLKKACYWLPGNHDYKPSMHSVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEYPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRIHLGARVMATPSTCVQFKPNSQDFALDNCSPGW
RELTLYADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A7U4FQZ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio anguillarum M3|TrEMBL
MNVSPTLDNSDSIKLLQITDTHLFAPDDGSLLSVNTVDSFHAVVAEICAQHVEFDAILAT
GDISQDHSAESYLRFSRGISSLEKTCFWLPGNHDFKPNMGAVFPSEQIQQSEHVLLGEHW
QMVMLDSQVVGVPHGRLSDQQLALLDEKLSTHHQRHTLIVLHHHPLLVGSAWLDQHSLKD
SDAFWNIVTQHRNVKAVLCGHVHQNMDKLHHGVRVMATPSTCVQFKPNSDDFALDRTSPG
WRELTLSADGQIETQVKRLANGAFQPDFNANGY
>A0A2U1UP01|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Brenneria nigrifluens DSM 30175 = ATCC 13028|TrEMBL
MESLLTLPVAHGARIRILQITDTHLFAGEHETLLGINTYRSYHAVLDAIQAQQYAFDLIV
ATGDLAQDHSLEAYRHFSRGIRRLSAPCVWLPGNHDFQPAMVDALAEAGIAPSKHVLLGD
KWQTILLDSQVFGVPHGELSDYQLEWLERTLQSQPDRYTLLLLHHHPHPSGCNWLDQHSL
RNAHSLAAILARYPRVNTILCGHIHQELDLGWHGRRLLATPSTCVQFKPHCTSFAIDDVA
PGWRYLDLMPDGQLETEVFRLQGNEFLPDMNSDGY
>A0A429GJE8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter haemolyticus|TrEMBL
MTYQVSTSSQQDFVMIQITDTHLLEYPHLEFVGMQPEQSFHAVIDLMRQQHPQIDLIVHT
GDLAQTPTPVTYNRYIQHMQSLEIPFFHTPGNHDDVAHFPFHEVDQTQLTVIELGKWVII
LLNSAQPQRIDGRITESQLKQLHTLLSKLHDRYVILACHHHPFAMQSAWIDQHKLKNASD
LMETVKPFSNIKAIVCGHVHQDAIHQWQGIEFLSTPSTCIQFKPKSEKFALDEEHPGYRY
ICLKANGELETQVYRLKTSERMSSSEVLGYD
>A0A3B4F617|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pundamilia nyererei|TrEMBL
MFKRMLNRELSQLSETSRSGNQVAIHDVDHPGVSNQFLINTNSELALMYNDLSVLENHHL
AVGFKLLQEDNCDIFQNLNKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTS
LGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDREREKGMEI
SPMCDKHNASVEKNQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPHSP
SPHPEGQEEEEEEEEDEEEGHSSSRRHEIYRSDSASPASRRLPKMLTSDSGRTFSLDSEK
DMAEERETDEGVSGVPRFRIGT
>A0A7J0AHW2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MEFHENMRFMKSLPLEPVGDVLVIAGDVGYLVDTTIPRLRFWKWASENYRQVLMIAGNHE
YYNNGDIAAQGESWQKMYMPNVGYYHNKVVRIDNVDFILSTLWSRIPPVDEMAIQSGMND
YAQILYNKRRLIPQNINDEFERNLAFVEKAVADSDAEKIVVVTHHLPTFAAIEDRHKGSV
LNAAYATELGNYIADSRISAWIYGHSHHLTDLTIGNTHLVSNPLGYLFCDENTAFNDSAV
IEV
>A0A7G9ZBZ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methanosarcinales archaeon ANME-1 ERB7|TrEMBL
MFRIVHTADLHLDPDYAYLAYNKLEERRLDFLKAFDQIIDFCIEEKPDALLISGDFYDKI
LPRNDPRVHIIERFKELNLKSRNTKVLVISGNHDTPKSRDEAKTPVDTLKALDNITVFDD
KTQFRKVVLKKEWKRLGIYGKSFYGLKGNLNPAENLPKCSEDFGIAMIHGSVKEMNPIYS
DYSQYAPFSVKDCVNKDFDYFALGHYHKFQSMAKKDTIFCYPGSTERYTFTEEQYEKGFI
WFDLDNDLSTDNLNFQKLDVRRMQTKEIEFNPRVEDINKFVLDNLIDKDPDVLLRIILKG
DVLFDVYRKYKINELQRELERSFFALRIENELNIKDVDMDYDFSSLRILTPIQEFENFVQ
DKIKLFKEEHNEVYVTLYEDLLKYGIEELKSLGVER
>A0A2Z4AF99|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Moanabacter tarae|TrEMBL
MSHYYDRTQLLPAEFEFVVLADTHYTRISPDTRVEFEGRRKQLTRIAHVLNLINSLNPEF
VIHLGDLTQEAPGSENFEISRQEALDQIERVDSKWHQVAGNHEVGDKPDATMPTHPVSRR
ILAAYHENMRSSWYSFNHGKCSFIILNSQIFNTGIPEENEQCFWLENLLVQLEGQRLFVF
MHLPLFILERTESYTGHYDNIGEPARSWLIELFQKHSVELVINGHVHFQFLNYIGQIRLL
TLGSTSFTRPGFAHLFTSASPPENAREDVAKLGFYLFRVLRNKVDVHFLRTGGDCKDLKI
LCKNQRLITLLANNLEDSPLGLTLRNPITNVSQIPIAYPSTIRQDVRNDYPLLSCFEIGV
KALRVPLKDIRDNEQWTRLSLLHDQGIAICVFLFESEIHKLPTIIEEFMDTVSNWEIQLP
GSIFPLAETIELLKDLQNKVKIEVSLCPVIPDQVIPGKQLPRTRFGYRLKELENIKSQLD
KINLQIMNICCRIGLDENPWDVIRLAYRLKNLGKARKLYFLIELGYQDDNRNSCRAVEAL
FAAALFRGTRIFFDPLIDIDRTMDVSLGILDTLCNPRPVFHAIRCLNTILYGLLQWEIKE
ENEIQWDGVKELQFINNGRKLSLLLPGSPKDENRDPPLKATSLLLKEQSFTLYLLNQGIV
LHEANEGHFIEMVAKVRNGEPCLIDIKS
>A0A857ELP1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mannheimia ovis|TrEMBL
MSEHFRLPINDTVRLLHITDPHLFSYTEETLLNVKTIKSFSAVIEQIKKQIEQTKQGFDL
ILSTGDLIQDQNIAGYHYFAQLTEPLKTPIVWLEGNHDVQPYMSQILGEYSHILPHKQIL
IGDRWQLLLLNTQVAGMPYGELSYRQLKWLEEKLNENPKRFTLIALHHNILPTNSAWLDQ
HSLKNSDELAKILQPFDHIKGIVHGHIHQQVDDMWNGIPIYATPSTCIQFKPNCNQFTLD
LLPQGWREILLYENGKIATTIKRLNSNDFLPDLNAVGY
>A0A6I8TT50|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aedes aegypti|TrEMBL
MPTSFIAIIITLTHTKDENGKPKAYTRTNSNGSAFRPRSLERGLLTAARRPHRRRVTSLH
EIIEGRPLDFDDRLISDLKFPNLLPPNPPIKILIAFCKNDPVFEALVTASHRLNFEPTFV
KSAETAIEAFQNAATGGHHIIVVDARYPRIIEADVLGRSIRNSKGSQHTTMVAVVKKNLF
EKDDTAVISLLDVGFNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQALYTALHRSR
EAVIITDDSLRAQYANRASEKVLNMKLDEIVGRSLNDLVTADISNILSHTTRHKDYEGFI
STRRKSQETLHIHVRAVPVSCIGRNPTHLVLILEQTSGTTLSALASDALQALPHGKEVAR
GSLHSIRRGSFDVRSTASDGLRRTSLAKLSQLPLEAPITKVLSLLAQVQENCSADESKLL
DRVMEFLKREGLYSPQMKEIRTEDPVATDLIGALLTQGPTNILSSRRSSNDSIIRGGGRP
STGSIVFNKTRESSQLSELLNSALSWDFEIFKLEELTEKRPLVCLGLELFRRFDVYNTFC
CDEVTFKLWLIEIEKKYHSDNTYHNSTHAADVMQATACYLQQLSNRETKVMDRMDEATAL
IAAATHDIDHPGRSSAFLCNSDDRLALLYNDICVLESHHAATTFRLTMADDKINIFKHLD
RESYKLARSIIVDMILATEMTRHFEHLAKFVSVFGTDVDSKETTHDNDDNQILIRRMLIK
CADVSNPTRPLKFCVEWARRIAEEYFTQTDEEKHRNLPIVMPMFDRTTCSISKSQIGFIE
YIIHDMMDAWNSFIEMPEIVRYMEHNYSKWKLFEEQGINTLSDIKRKQLTLNSETTGSSS
IEEL
>A0A358L7M9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia citreus|TrEMBL
MDSLLKLPVANGRARVLQITDTHLFAGKHETLLGVNTWASFDAVLQAISACEEPFDLIVA
TGDLAQDHSVEAYQHFAEGIARLPAPCVWLPGNHDFQPAMFNTLAEAQIANEKHVLLGDQ
WQIVLLDSQVFGVPHGELSDYQLEWLEKALAKAPERHTLVLLHHHPLPSGCTWLDQHSLR
NAHMLEAVLQRYPLAKTLFCGHIHQDLDLDWNARRLLATPSTCVQFRPHCTNFTIDSEAP
GWRWLDLHADGLVETRVERLTTRAFSPDPDSEGY
>A0A2M8RUM9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Caviibacterium pharyngocola|TrEMBL
MVNTYTYHTSENVIRLVQITDPHLFKDEKGELLGINTQASFNQVLTEIGQSDFNYDIVLA
TGDLVQDSSDEGYLRFCENVKSLQKTVFWIPGNHDFQPKMFDILNQHHGNISPIKHILLG
EHWQILLLDSQVFGVPHGQLGQYQIDWLEAKLKEHPQRYSLVVLHHHILPTNSAWLDQHN
LRNSLDLAYTLAPFAKVRGILCGHIHQQIDGEWNGYKIMATPSTCIQFKPDSNSFALDTL
QPGWREIELHHDGRIETRVKRIQHAEFLPNMLGDGY
>A0A2H6ATN7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR39|TrEMBL
MEIAFLTDLHLPLPAGGPAALLRLPWTFGPRAFANKRASGLLSWALRRSRRHRHEVLDAV
LADIARDPPDLILVGGDLCNLALPEEFEAARELLERLDGIAPVRLVPGNHDAYVPGALET
YGRLWAPWTEGRVVRDDWPWLCDLPQYGVAVIGLSTAVPRPWGDAGGEIGEAQLRRLEEA
LAAFAGERLRVVLLHHPPHERTSAHKRLADRRALLDLLARRGAELVLCGHLHRLETDGLP
GPDGPVPLLQGPSASQLDERRPGGYLRLRLAAAPRRLVVEPRLFRDGALRAEGPFTPGPP
AAAAARTAEVAAP
>A0A2K6DDB9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Macaca nemestrina|TrEMBL
MARPRGLGRIPELQLVAFPVAVAAEDEAFLPEPLAPRAPRRPRSPPSSPVFFASPSPTFR
RRLRLLRSFQDLSRQAWAGAGFEAENGPTPPPGRSPLDSQASPGLVLHAGAATSQRRESF
LYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPTN
KRSPLGGPTPVCKATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRML
NRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQALRPRPSQPPPPPV
PHLQPMSQITGVKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYA
GGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTH
VLLATPALDSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPPPDKFQFELTLEEEEEEE
ISMAPIPCTAQEALTAQGLSGAEEALDTTVAREASPAQESLDVMAQDESLEAELEEVYLT
QQAQSTGSAPVAQDEFSSQEESVVAVSQSSLSSLALQSPLLPAWRTLSVSEHAPGLPGLP
STAAEVEAQREHQAAKRACSACTGTSGEDTSALPAPGGGGSGGDPT
>A0A636KBL8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Uzaramo|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A093RL15|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium betavasculorum|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKARQDVFDLIV
ATGDLAQDHTLQAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSAVLDRYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDNVS
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A2K6DDC9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Macaca nemestrina|TrEMBL
MPLVDFFCETCSKPWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVE
IPSPTMKEREKQQALRPRPSQPPPPPVPHLQPMSQITGVKKLMHSNSLNNSNIPRFGVKT
DQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYM
LTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDSELALMYNDESVLENHHLAVGFKL
LQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDK
HTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEE
ESRGPGHPPPPDKFQFELTLEEEEEEEISMAPIPCTAQEALTAQGLSGAEEALDTTVARE
ASPAQESLDVMAQDESLEAELEEVYLTQQAQSTGSAPVAQDEFSSQEESVVAVSQSSLSS
LALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACTGTSGEDTSAL
PAPGGGGSGGDPT
>A0A1C7F5T3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio scophthalmi|TrEMBL
MKVTSSSSTKDTIKLVQITDTHLFAAEDGSLLSVNTNDSFSAVVEAVTQQDFDFDAILAT
GDISQDHSDVSYQRFAQGIEPLKQPCFWLPGNHDYKPSMGSVLPSTQIVQAEHALLGEHW
QMILLDSQVEGVPHGRLSQQQLDLLDEQLRLHPERHSLVLLHHHPILVGSAWLDQHTLKD
AEQFWQVVEKHDNVRAILCGHVHQDMQKVRSGATVISTPSTCVQFKPNSDDFALDTCSPG
WRELTLCADGQFETHVQRLAGGLFLPNFDSSGY
>A0A5E4K4Q5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MEKDYLLIGKTLFFPKKGILAIGDLHLGFEYQLQQSGILVPEMQIKEIKEELKKIFEEIE
KRKLKLKKIIFIGDLKHSFSYQWREKNYFNDLLKFLREYVKDENIILIKGNHDTIDYSFS
DRLKDYFIEGEIIFSHGHQLFPEILEKKIKTIVMGHLHPSIIISDNQGIKKEKYKCFLVG
KFKQKNVIILPSFSLQ
>A0A4P8YD90|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Jejubacter calystegiae|TrEMBL
MESQLNLPVAGGASIRILQITDTHLFADKSGTLLGVNTWESYQAVVAAIHARQNSWDLIV
ATGDLAQDQSAQAYQHFADGIAGFSVPCVWLPGNHDFQPAMYSALQDAGISPAKVVYAGD
AWQILLLDSQVFGVPHGELSDYQLEWLERQLSRAPERHTLLLLHHHPLPSGCSWLDQHSL
RNSPALDDVLARWPRVKTLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIP
PGWRWLELAPDGTLTTEVCRLETQDFSPDTESEGY
>A0A6P4I6Y5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila kikkawai|TrEMBL
MIISSQPNLAGSATSTTPSPSTNPNSNPSSHTNPSAAAAHMGDESVPSNCNCNVGVDLVG
IGARQSPVPALEAAGRDSLMRPASDESELNVGTGTSGTSSSGGGNSHRHRKSSLALALTP
EDEPMDVYQRNLMDLKYPTVLPPNPQLKALLVFHKADSICEAVTAACQRHQLDVTLVKSK
EEALDTLQKSYATAQCYHLIIIDARSAKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFE
KDDVLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEV
VLITDDVLRIQYANRATERLLNMRLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTV
RRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRR
CSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLK
REGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKM
KANPIIMELLEESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWL
AVMEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDMLVMDRMDEATALIAAAAHDVDH
PGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARST
IIDMILATEMTRHFEHLAKFVSVFGGEEPREQHSQTEEETSILMRRMLIKVADVSNPARP
MQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAW
ESFIDMPQLITYMQINYSQWKKYDEQGVNTLADIMAKQPPVGKMANSK
>A0A5E4IWS5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKSSLRILGLADLHDRVEMLDRVRETDADLIAFCGDLHNGSSRTAAEPVAAALARLGLPV
LIVPGNMDHRDVVDQMWREAGLIMLHRSSFRFREYGFLGMGGMAVHNPRRLQDPARYYHR
DEEVYDSLAQAYLSISGSKKIITLTHQPPRDTLDTIYTGERTGCISLRRFLEEYQPDLLL
CGHIHEDRGESQVGPTRIVNVGELRQGSAAIIELNGEIAVDWIEL
>A0A8C5AQD0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gadus morhua|TrEMBL
LLTNPLVADPGSTPLCKMGLSAPSSDVGLSPRCSSDVENGLSGGRSPLEARPGLVLQAGQ
RRESFLYRSDSDFDLSPKTSSRSTSSPGDLHGEDMIVTPFAQILASLRTVRSNFASLTDL
QDRGNSKVQLPYLSKSTDTPC
>A0A806DM08|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae (strain R2866)|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNEFDVILA
TGDLVQDSSDEGYTRFVEIMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAEFLPNMQEEGY
>A0A1A7XWT0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Iconisemion striatum|TrEMBL
MGVVETIDPEPSPCSSPVPGGYRLPRSSSYSPLQGRPGAELDLGAADGGVREGGGTAAER
RTPLVDLFCETCSRPWLIGWWDQFKRMLNRELSHLSEMSRSGNQVSEYISTTFLDKQNEV
EIPSPTLREREKPMCHISGVKKLTHSSSLSNSTLPRFGVKTEHEEALARELDDLNKWGLN
IFHVAEFSNNRPLSCIMFAIFQERDLLKTFRIPVDTFVTYVMTLEDHYHANVAYHNSLHA
ADVTQSTHVLLSSPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFL
>A0A8C1F088|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyprinus carpio|TrEMBL
MPEANYLRSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHDVEMPSPQT
QKEKEKKKKPMCQISGVKKLMHSTSLTNSNIPRFGVKTDTEDSLAKELEDINKWGLNVFK
VTEFSGNRPLTVMMHTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHSNIHAADV
TQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTNRIQVLQNMVHCADLSNPTKPLQLYKQWTDRIMEEFFSQGDRERERGMEISPMCD
KHNASVEKSQVAIEVLELCFYRLPYYESKIKQLIVR
>A0A8C1DUC9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyprinus carpio|TrEMBL
MNSAVYQKILKENVQPSVRDLKLKRTWVLHFDVENGLSVGRSPLESQASPGSGLVLQANF
PHSQRRESFLYRSDSDFDLSPKAMSRNSSTASELHGEDMIVTPFAQILASLRTVRSNFAV
LTHQQDRVLSKNHPALVKAKKI
>A0A223U5W9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella quasivariicola|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVFLGD
HWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAEFHPDIASEGY
>A0A7R6V935|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nitratiruptor sp. YY08-13|TrEMBL
MLPKKEAAMQRRDFLKATLTLPLAFPLFAKEDEKLRFLHITDSHMDLSMPHTVKAMEHLA
DVVNTRFSHIDFVLFGGDNFNNTAPSDKDAKIFKAFLEKMKVPCYCVRGNKESSPKGDNS
IDAGEFARLFFDQKGMRVSGRDWMVEHKGYLILGLDSTIEHSGAGIYTKETITFAKKALS
KGKPTIILNHHPYLNYWHGTDPKDIHKYVLQNTKEVQEQLFRYPNLILTLSGHKHIDNVS
RIGHVTAIASRAFKAAQILYQNPMRYIEIGRGGIKEKLITT
>B8K9A4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. 16|TrEMBL
MKVTSNSSDSSIKLLQITDTHLFEATDGSLLSVNTGESFKAVVNAIVEQECRFDALLATG
DISQDHSEASYQCFERGIEPLLKPCFWLPGNHDYKPNMTSVLPSPQIQQVDHVLLGEHWQ
MILLDSQVIGVPHGRLSDKQLALLDEKLAQYADRHTLVLLHHHPILVGSAWLDQHTLKDA
DDFWQVVQKHDNVNAVLCGHVHQDMNVMHHGVRVMATPSTCVQFKPNSDDFALDTTSPGW
RELVLKADGQLETYVKRLPAGCFQPDFSSAGY
>A0A2J9UYJ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio mimicus|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFAAEDGSLLSVNTADSFAAVVAAIGEEKVEFDAILATG
DISQDHTPESYQRFVSGIQPLQKVCYWLPGNHDYKPSMQSVLPTSQIQAIEHVLLGEHWQ
IVLLDSQVVGVPHGKLSDQQLQLLETKLTQHSERHTLVLLHHHPLLVGSAWLDQHTLKES
EQFWAVVAKHSNVKAVLCGHVHQDMDRLHLGARVMATPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQIKRLKQGRFLPDFNSNGY
>A0A7C1Z2X2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sedimenticola sp|TrEMBL
MTKPDNTLRSPLIEDLVGLPAGSLRVLQLTDTHLFADPEERLLGINTLESLNLVLECASR
TLGPMDLALVTGDLVHDTSAAGYSCLHQRLATLGIPVYCLPGNHDEPAIMAKWLEGNPVS
APALVEQNNWLIVLLDSKLPGSEGGHLDETQLAHLESCLAAHPAKHALVCLHHQPVSVGS
TWIDTMELDNADEFFTIIDRHPQVRGILWGHIHQTYDSKRNGVPLMGTLSTCFQFTPREE
GFGIAKEPPGCRWLVLLPDGTIKTGILQIDSMSDTIDLSSTGY
>A0A7Z2XL49|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. ADAK13|TrEMBL
MSSVSALNPDASALLVQLSDSHLFAEADGGLLGMKTRDSLQRVIETVLAQQPQIDLMLAT
GDLSQDGTLESYQAFRDMTRQIQAPARWIPGNHDEPQVMLQAAVNSALLEPVVDVGNWRI
TLLDSAVPGSVPGYLQDQQLQLLAQSLSEAPTRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEEAPGYR
WLRLHADGRLETGVERVQGFAFQVDYGSSGY
>A0A494WIH2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clostridium scindens (strain ATCC 35704 / DSM 5676 / VPI 13733 / 19)|TrEMBL
MFKLGKRVCAGIMAAVTLGVTLLPGVESYAAAEDLTENLKICVISDTHYYPLNYVSDCED
YKTYVGGDPKMLAESGAILDSALDMIKTDQPHLVLVSGDLTKDGEKLGHQNMAKKLQTIE
DKTDAEVFVINGNHDIYNYQDSCTFENGKKEQATTTTPAEFKEIYGQFGYNGEYDAQYYT
PPTGKQAGGLSYSVTVGDYVIIGIDSGRYSPDADTGMDTNEHITAGRIDTSLLPWVEQQV
KDANAKGKTVIGLMHHGLVPHFSKEAELLSEYVVDDWQEMASTLADAGMRYIFTGHMHAN
DIAEYTSVKGNKIYDLETGSLAAYGSPVRTVTIQRDQTMTDQSTLQLDETFHVKSTSVKS
INYNGATIDDLQAYTMNKLYPETLFNNMAGGMLKPMIQDVADTGIRNYLAEEMPELDIDT
IVLDTVREMLAGGMNLELGSGIGRVAVSYRNGGIELKPTGTAGLIGTTTISDAQIIRVVD
DLLAKVENQYLKNPDYLLGKVNEIVTKVSQFGVGSLDGQEKTLYDFIVLLLTSHYAGGEN
PPAWVTEQALPYLRSGAVIKDLMDMLVGDVVVIVNDIAANLNIDTGIAFSGLWKTAIDSQ
TNNGNLATILKQFNLNVEELINGLISEYMSDSFLTGMGGLLDNYASSFLYDTESPDDILN
DENGRTITWSTSTPVTPQEPSVANGLAPTQIAMTQGESADSRYLRWYTGAGVSGTAVAQI
SESGDFADAATFTAETQEVVKPKTLLNLGLMATYTTQKARKYTAKITGLETGKTYYYRVG
ISETGNFSTPVAFTVKNEETSGFTFINVNDSQGMIASDYETYLNTLAEAKSQFAGAAFVL
HAGDFVDDGSNEDYWTWALEGVSEAVSYIPSAGNHEAKSSVEGITDPNAIISHFQVQNQD
IPNQDTSTGIYYSYEYENATFIVLNTNDVTDDGYLSDAQYDWAYEKAENAQTDWKIILMH
KSPYSNGPHAKDADVVAIRKQLNNLAADCDVDLVMSGHDHVYNRTPYLAQGKTQQVTTRT
TSYQGNNYTTAVNPSGTVFVIAGTAGVKNYVQTPVSTVPSEKTFQQTCPVYAGVTIDDGK
LYYRAYQVKDGVSQLVDSFAIDKSKETEVPEWKKVEDMIAELPDTPTLDDASEIQAARAA
YNALSDADKAQVANVKRLEQAEKMLRALQSINGKQTRHVNSKSEFLNALKDTNVGTIITD
GATIEFEDEYWWGGAYDNVWEITRDLRIMGSSKLTYVTFRVKNGATLILDGDIAIDDTRA
QGSGYASLNPVEVYGNSTLITSGHVALRTEYGTGGENEGVCVKMMENGSKAILGSDGSYY
GAEAAVLSIGSGTEVIINAGTYARKNNNHRAVDSRGTIEVNGGEIANLWSNGALYINGGT
FDNGSNLNPQIPVDIEGTAYMTGGRITPYNGNGVKLRSTGKLHILTGSIGQASIGNVQPY
VGAVTTQNYKDIEVGYHNINGSGNSDGIYEASAAAGTVESLANANGTKLAGSAVADGRMT
GTLGEGDHHVYGKYYLAGGGKTAATGFSVDSGGEAIVYGPSRFIENYRVTDAVIEGEATR
LVQYQDGAVIRLNGYTLPANAFDNAVSWTSDNAQVATVDRGKVTLKKTGTANITMTSQSN
ASISDQVKIMAVDPVINGEELIEDDAPQTYTVDLQATGIDETDRNRISYKWSVDDLKVAT
IDETTGELTKVGQGTVHVTAQLLLDGVATDIRVSKEVQVRDVISVEITWGAMEYTYDDGQ
WNKDTHQYDGRGWTADTSEGDQIQVKNTGKEAVAARFAYLAEEGYTSIDGRFVKDNSPIT
ADTLQPQEKMKVQLQLNNKPDKKMDKTTVGTVTITINRESTN
>A0A2S9YYR0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enhygromyxa salina|TrEMBL
MAPVPQRSRATVAARQAHTRGVLLFPAFMTPLVYLEGREAEPWLELLIATERDLTREMVN
DQLKISMGLRSEKPVSVAPLFAGAAGNIIVESAGEVDDDGEDIISTHSKFSGILHPSYGE
ALRAKNVKKVFRVKIRASALPTECPVNEINYSFRERKWTEYARREGRSDRFTRMARVGSE
LSDQMIREMTTRRFGADNSSNPNSLPGRGRYAFPMHGNTVDIHRIDPEQPIQSYHPVFVL
TGDDATAYLNFGHVSDIHINTRWQLLGKSNARVIEYGAGQYEDESPEIGGLLAENNRSFH
AVLGRVAGGDADVVIVGGDIIDHIRNAYDPDVVLEANNTPREIWDAMNLEGSAYTQATYP
VGIDLLAFYSFIFDAMTRHSKPVFGITGNHDCYVDAFGISPRLNAEVMASRTNEGIPADL
NLTFYEALLAFGPSAGLLRSPSSSFDADWFDWFHQVLTPFNDWWFKFPQQSLVGLGWGTS
EDLIDPFGGQSGGHLPRSDDAISDPQLALLQQAVNGRAERRVTLTSHFTFLSYIEGEPMN
PGGARSARGTFRLNADSWGTEDYSRFEMGTFETNRATLMNMLAGRQIQCVLTGHSHRRGM
HLLGTRAGNEIPADLYDTDPNNPHNMCQIPAALPNGEPVIIVSDSGGPYPRYNRNNEFLG
WGSDRPGGTLVKFSQNSGRLTDVRTLTATSRRKARGAVVMDYVDVSAEGAFNNNRMQTQR
VPADVNSGAVTSAAPVWYIDANLTTQVHTTWGMYIEKMIFAGRHAGRWIHVEATYNQPRN
AFEVPAAQTDDFRLWLRNVLQPTRYVSIKMGSRDAFISGRYDWGSFWNFEVLAQPIFEHH
RNALGQTIRYVSYRILRPQREIEITGRNISWRESPNFDWRMANDPKYAR
>A0A0X1KZ89|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cholerae (strain MO10)|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFAAEDGSLLSVNTADSFAAVVAAIGEEQVEFDAILATG
DISQDHTPESYQRFVRGIQPLKKACYWLPGNHDYKPSMHSVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEYPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRIHLGARVMATPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A182WJV1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles minimus|TrEMBL
MKDDSETVNGCFKMKSFFRKYQSKSMESLCKPPTPTVLTVKQLESMPQAERIRPARRYSL
IGTPSSTGFPPHSTGEERKVTRKVSSAQHGNIPEEKRNGALDTDLLLMEEMVKKLVDNGD
SLITGPKLTTELINSPESRRSLPLERNQHVLSSDNGCEQKVYYRTNSAPIFRPRSYGRRS
NGLKVFRFPDIMEESPFAEPMILSAREWRRFAAFRSLPADSIDPAYRQHILANYDVHFYE
YGELKPRDSSPRDAVMFSVDRPEPGPSQQQQSPVPEQSDGKQQHQLADVVTGHGSKEAVE
DEMLPSLSEEEVQFIERLVSDLKFPNLLPPNPVIKILIAFCKNDPVFDALVNASHRLSLE
PTFVKSAESAIEAFQNPSSGGHHIIIVDARYPRTMEAEALGRSIRNSKGSQHTTMVAVVK
KSVFEKDDTAVISLLDVGYNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQALYTAL
HRSREAVIITDDTLRAQYANRASERVLNMKLDEIVGRSLNDLVTADISNILSHTSRYKDY
DGYLTTRRKSQESSQIHVRAVPVSCIGRNPTHLVLILESSSSALVSSNAIGEALQTLPQG
KEVPRGSLHSIRRGSFDVRSIASDGLRRTSLAKLSSLPLEAPITKVLSLLAQVQENCSLE
EAKLLDRVMEFLKREGLYSPQMKEIRTEDPVATDLIGALLTQGPTNILSSRRSSNDSIIR
GGGRPSTGSIVFNKTKESSELSDLLQTALDWDFEIFKLEELTEKRPLVCLGLELFRRFDV
YNTFNCDEMTFKLWLIEMEKHYHSENTYHNSTHAADVMQATAVYLQQLSNREIKIVDRMD
EATALIAAATHDIDHPGRSSAFLCNSDSSLALLYNDICVLESHHAATTFRLTLADDKINI
FKNLDRDMYKLARSIIVDMILATEMTRHFEHLAKFVSVFGTDVESKEPLAPDNDDNQILV
RRMLIKCADVSNPTRPLKFCVEWARRIAEEYFMQTDEEKRKNLPIVMPMFDRTTCSISKS
QIGFIEYIIHDMMDAWNSFIEMPEIIRYMEFNYSQWKLFEEQGINTLSDIKRKQMSLNEE
TASSISLEEKF
>A0A553QG32|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Danionella translucida|TrEMBL
MTVLKRLNTHYLLFYLSSFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYR
SDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFAALTNVQQERTNNK
RSPMCNPPPITKTSYTAVRVSDPDRKIPLQLFIAAFLSVEPVPSHGLVYDVALSTRRMSL
TSAQALAGILSLSPACSGTARLHACASRGSCAHVRLATLLGCPSLVQGIHCLEKRGQANA
RSFVLFCDRTGDRHKTLICWRQPSVCFAFVLVCVCERVYVCVIVMTLCLCALLWAGLHTP
EGQRTTLGFSDVDRHLSRRDDGPTFFFGSIWSPIFHCGGLQHSMKNHPCVLSGYPNMAVY
SRLGPLLGASARPLQHLRSDCLLHSLPPEEAYQKLATETLEELDWCLDQLETLQTRHSVS
EMASNKVRTSSSLSLAEFTLEALG
>A0A5E7TZ53|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEADGVLLGMNTRDSLQKVIELVRAQQPRIDLILAT
GDLSQDGTLESYQQFRDMTRQLDAPARWIPGNHDEPQIMAEAAVQSALLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFEQVRAVLWGHVHQEIDRMRNGVHLIASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGRLETGVERVTGFDFTVDYGSNGY
>A0A5E6VRV1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADAALLVQLSDSHLFAEADGTLLGMNTRESLQKVIELALAQQPQIDLMLAT
GDISQDGTLESYQQFRQMSAQIDAPARWIPGNHDEPTIMAQAAVQSTLLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDDQLQLLARSLSEAPERHHLVCFHHHPVPIGCAWAEPIGLRNPD
AFFEVLDRFPQARAVLWGHVHQAFDRERNGVRLMASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGRLETGVERVTGFAYTVDYGSNGY
>A0A5E6P7K8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPQPSIPLSAVPVYLVQLTDSHLFADPQGTLLGMNTRDSLQRVIERVRDEQPRIDLLLAT
GDLSQDGSVASYASFHELTKSLGAPARWLAGNHDEPVPMEQAATGTDLLSPVVDMGNWRI
LMLNSAVPGAVPGLLDDDQLSLLEQALREAPERHHLICFHHQPVPIDCAWMAPIGLRNAD
ALFAVLKGYPQVRALLWGHIHQEWDQVRDGVRLLASPSTCIQFEPGSDDFKVGEQAPGYR
WLRLQADGSIDTGVSRVSDFEFSVDYEGDGY
>A0A5E7KUV3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEAGGSLLGMNTRESLQKVIELVLGQQPRIDLLLAT
GDISQDGTLESYQHFREMTAQIDAPARWIPGNHDEPMIMAEAAVQSALLESVVDLGNWRV
TMLDSAVPGSVPGYLQDDQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQARAVLWGHVHQEIDRQRNGVRLMASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGRIETGVERVTDFAFQVDYGSNGY
>A0A1V3IFN6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rodentibacter mrazii|TrEMBL
MKNTFVYRTEKPMVKLLQITDPHLFKDEKNELLGVNTQASFAQVLKEIQQENTEFDAILA
TGDLVQDSSDEGYQRFVNMVKPFGLPVFWIPGNHDFQPKMVENLNQPPMEKAKHILLGEY
WQVLLLDSQVYGVPHGELSQYQLDLLKTTLEKYPEHHTLIVFHHHVLPTNSAWLDQHNLR
NSHDLFDVLSPFKNVKGILYGHIHQQVDSSWQGYQVMATPSTCIQFKADSQHFALDEVQP
GWREIELHSDSTIVTTVKRIRQARFLPNMQEEGY
>C3XY61|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Branchiostoma floridae|TrEMBL
FDVENGPPPSRSPLEAASPSSGLILQANFPQRRESFLYRSDSEFELSPKSMSRNSSIASE
HESDLIVTPFAQVLASLRSVRNNFISLTNVPASRLVLIFSSSNNKLTVPDENQSRLAMET
LEELDWCLDQLESIQTHRSVSEMASSKFKRMLNRELSH
>A0A736MG67|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. houtenae serovar 44:z36[z38]:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLASFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A231H741|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nocardia cerradoensis|TrEMBL
MILLAQLSDTHFDLDPRNAERVAAVLGYLDRLPRRPDAILVTGDLTESGTLAQYEQARKS
LTTDIPLYVLPGNHDDRANLRQTLLDGPAEDGPINQAVEVGELTVALLDSTIPGSGGGEL
GERTYAWLDRLLAATPADASVLVAMHHPPVPMYSTVVDPIRLADPERLERTIAGDARILG
VLTGHMHAMGTTLFGGRQLVVAPSVASAIGGAWEVEEPGDVPIDYAPDPSVVLHAVADRR
LTSIVRTVPMGGRIRVQPR
>A0A0H3CQJ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae subsp. cloacae (strain ATCC 13047 / DSM 30054 / NBRC 13535 / NCTC 10005 / WDCM 00083 / NCDC 279-56)|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQEAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPARHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLAKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLAGAQFRPDTASEGY
>A0A6P8F0N1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clupea harengus|TrEMBL
MKKSRSVLTVTGEEDHDTSEGGEKEEESARYSRSYTSGSTLGAELRRGRSHRLSSSLQVP
CWLRPRDRTRSPEVLMPRPTTLPLRIPPRIDITQPDPDSFELENGVSPAGRTPLDLQASP
GVMLHPSFPQGQRRESFLYRSDSDYDMSPKTVSRNSSIAGEGHTAEDFIVTPFAQVLASL
RSVRNNFTLLANVSSPTVKRSPVSIPSPGPKSSLSDDQYQQLAVETLEELDWCLDQLDTI
QTHRSVSDMASSKFKRMLNRELSHLSEMSRSGNQVSEYISSTFLDQQNEGELPSPTLKEK
PMSYIPGVRELSHAHAHALSLATLPRFGVNTEHEDELAKELKELDNWSFNIFRAADLSNN
RPLSCIMFTIFQKRDLLKTFQIPVETFVLYVMTLEDHYHSNVAYHNSLHAADVTQSTHVL
LSSPALNAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLA
VGFKLLHQENCDIFQNLTKRQRQSLRKLVIDMVLATDMSKHMTLLADLKTMVETKKVTSS
GVLLLDHYTDRLQVLRNMVHCADLSNPTKHLSLYRQWTERIMQEFFRQGDKEREKGMEIS
AMCDKHTASIEKSQVGFIDYIVHPLWETWGDLVHPAAQDILDTLEENRDWYQSTMPQSPS
PPLDRNQLGPPADRFQFELSLEEDAQQNQNSSSYRNHNSREERNGNGNRQDPNCNNGCYG
DSEEVSNHVDHNHVDENHVEAEEDAEEDAADGELENAEQDQNQMEELDGEGEPEENHCET
EEGEGEEEAYW
>A0A077NWR0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus bovienii str. feltiae Moldova|TrEMBL
MESLLKVPVAEGATARILQITDTHLFASKGDALLGINTYRSYHAVLDAILEQSIDIDLIV
ATGDLVQDQTIGAYQNFAEGIARLPVPCVWLPGNHDYQPAMVDVLAAAGISPSKQILIGQ
HWQLVMLDSQVQGVPHGELTDYQLEWLQKCLDEHNDRNTIVMLHHHPVPSGCTWLDQHSL
RNAPALAESLKDKRQVKAILCGHIHQELDKMWNSIRVMATPSTCMQFKPHCTNFMLDTVA
PGWRYLELSVAGNREARLQTQVHRLKSNEFCPDLDSDGY
>A0A4Q7CWX5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas orientalis|TrEMBL
MPSVSAMNPDAVLLVQLSDSHLFADADVTLLGMNTRDSLQRVIDLVREQQPPVDLVLATG
DLSQDGTLASYQQFRDMTAPMGAPARWLPGNHDEPQIMAHAAVHSDLLEPVVDVGNWRVT
LLDSAVPGSVPGYLQDQQLQLLVQALSEAPNRHHLVCLHHHPVSIGCAWMEPIGLRNPDA
LFAVLDRFPQVKAVLWGHVHQEIDSERNGVRLLASPSTCIQFAPGSEDFQVSDQAPGYRW
LRLHADGRLETGVERVRDFAFTVDYGSNGY
>A0A5Q2T3S1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kluyvera intermedia|TrEMBL
MESLLNLPLAGGASVRVLQITDTHLFAQQDETLLGVNTWESYHAVLEAIHASARDVDLVV
ATGDLAQDHSSAAYQHFADGIASFSVPCVWLPGNHDFQPSMYSTLQEAGISPAKRVLVGE
NWQILLLDSQVFGVPHGELSDFQLEWLEKRLTQEPERHTLLLLHHHPLPSGCSWLDQHSL
RNAGALDGVLARYPRVKHLLCGHIHQELDVSWNGRRIMATPSTCVQFKPHCSNFTLDTVS
PGWRWLELHADGSLTTEVCRLAGVKFHPDTASEGY
>A0A7L4ZQ49|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kordia antarctica|TrEMBL
MRIVHLSDIHYSRDRLDEFKDYYFKALLEDLMSIHKERSIDLILITGDLIDKGGVSFEEE
NYYKVFQDEFLNPISKALSLSNEQIILIPGNHDVNEELIEKYHEMGLIVGLTSSDNVNEY
ISIHKDSKEIQIKRIVNYMNFTREFYSNKNAGYISQFETCLIYEKENVKVGFACLNSAWR
CSSVIEEKQIWLGTNQILSANTFLDKENCNFKIALLHHPISIFKNREEKEILSFLKRFEF
QAVLGGHLHESDSYVNTSRDGELLISNAKSGFNNPREKIESYQSGYSIIDYNFQTLINTV
VHRKYFHNRIAFDKDLSFAKEGKFERKFSFKSKTNDTNTKEIVTQNDANKTSAKTNPFHI
SLDVLNNKKDFYLSNLFIRQDTVYNDFEKKLSSRGIVIIEGPQLSGKTEFIRNYFSKNDN
YQFIDTIPEKIFITKKRKHPYTDVLDLYTEWGRAILDKATKQFNIDTTANPGIWELISEK
EEFKKKIIANRDFSKYENDLECLFRVLNNALEETVNFQNRTEKLIMSAHLDNFESYADPR
TFDSLIEDLGKLNLREVKDGILKKMGLVISTRYFPSNQLKNIVLKMNNFSLEDIKNFYYS
VFEDNEKNSKEIIDLIYHYTNGHVWFVKRFFILFLTLVKENPKKSILELTNSIFNNPKYW
IMDSFNGYTKHSEFIRVIEDIYNNHTNHQDDFYNCINEKNPNNERLSTYKNNSIVIETGI
LNRKKKGFREVIINGYCNRIFSDFYLDYLIDNLY
>A0A7W4LLG2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas ullengensis|TrEMBL
MSHAVDPSVLLVQLSDSHLFAEEDGKLLGMNTRDSLERVIEKVLVEQPQIDLMLATGDLS
QDGSTASYQRFRQLTGALADQARWFPGNHDELPAMRDACNGSNLLEPVLDIGNWRVTLLD
SSIPGAVPGFLSDDQLKLLEQSLSEAPDRHHLVCFHHHPVSIGCTWMEPIGLRNPDALFA
VLKRFPQAKAVLWGHIHQEFDQMRDGIRLLASPSTCVQFAPGSEEFQVDTTAPGYRWLRL
HADGQLETGVSRVTDIQFEVDYSVKGY
>A0A4Q8WYZ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
THLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIVATGDLAQDQSSAAYQHFAEGIA
SFSVPCVWLPGNHDFQPAMYSSLQEAGISPAKCVFAGEQWQILLLDSQVFGVPHGELSEF
QLDWLETKLAAEPARHTLLLLHHHPLPAGCSWLDQHSLRNSAALDSVLVKFPRVKNLLCG
HIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIAPGWRWLELHADGSLTTEVCRLA
GAQFRPDTASEGY
>A0A1Y0HM92|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sulfurospirillum sp. SL2-1|TrEMBL
MIKLFLSLAFALCLYAAPLSHIVVLGDPHLPGKNVPMKEHVIEQINQWNDVDMVVAVGDI
CSKTGTQEEYDFAKKYFSNLTKPLHVITGNHDFVYADALDSNGKFQHATREIQDEKLKRF
QSTFGLSKLYYSIEKPPYLLIFLSADDPKYLTKLSDEQLSWFENELKNHPKTPTIVFFHA
PLDHTLENYNHWANTPNFIAQPKDKIQTLLHDNPQLFLWVSGHTHTSAKEPSFASTINQV
EHVTNIHNADMNKEVIWTNSLFLYDNHVTIKTYDHMEEKWLDTLERTVFVPKI
>A0A1S3KYI6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmo salar|TrEMBL
MAMTDTEDSDQLRNAVCSEGATIGRYEELLQNLMEGFQTLVERGPLCVTNNHPASSPLSQ
FKRMLNRELSNLSQMSRSGNQVSEFISRTFLDKQHGAERPCPQMQKVKMDKKNAKPMCQM
SGVKRLQHSTSLSNSNIPRFGVKTGTDDKLATELEDINKWGLNLFKVTELSGNRPLTVIM
YTILQERHLFKTFKIPLDTFITYLMTLEDYYHGDVAYHNNIHAADVTQSTHVLLSTPALE
AVFTDLEILAAIFASAIHDVDHLVFPMICNSELALMYNDSSVLENHHLAVGFKLLQEENC
DIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYKDR
IQVLQNIVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVQ
KSQVGFIDYIVHPLWETWADLVHPDTQDILETLEDNREWYQSTIPQSPLPAPDKSDHSSG
RLPGAKFHFELTLEEDRETDTEKDSRSQPEEGEEEENSCDSKTLCMQDSESTEILLDEEE
EEGEGGRRVPSMVELVEGEGKGKEKGEEEQRAADT
>A0A7T7BFF5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ralstonia pickettii|TrEMBL
MSKQPGRRQFLQLAAVGGLVYASGLPGWQAMAATTRAAGAKPDDFYFVQLSDTHWGFKGA
PNPDSQGTLPKAIAAVNALSPPPDFVIFTGDLSHISDDPAERRRRLAEFRDIAAKIKVPV
VHYMPGEHDASLDNGEAYIELFGRTHYAFDHKGVHFIAIDNVSDPSARVGDAQLAWLAAD
VRSVPEHTPIVVFTHRPLFDLYPQWDWATRDGQQVIDLLMPHPNVTVFYGHIHQEHHHMT
GHIAHHSARSLMFPLPAPPAPGSQAKRNPIPWDAAAPYRGLGWRSITGHGKQDAATWALA
EQPIQPNSEATAAKTPETT
>A0A1T4UP88|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterovibrio nigricans DSM 22720|TrEMBL
MRICHLPKQHNQTVRLLQITDTHLFADHAGSLLGVNTSASFKAVVNEIVQDGVEFDAIIA
TGDISQDHTAESYQRFVSGITRWEQPCYWLPGNHDYQQKMNAVLEQSTLERCEHVLMGEH
WQLVMLDSQVAGVPHGRLSDEQLMLLEVILRDNPERNTLVLLHHHPLPAGSAWLDQHKLH
NQDAFWAIVAKYNTVKGVVCGHIHQALDTQYQNCRVMAAPSTCIQFQPNSDDFALDLTNP
GWREISLHADGSISTTVGRLKGNEFQPDMTSSGY
>A0A2M8HD20|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas lusitana|TrEMBL
METELPQAPDGSVRLLQITDTHLFASAEGRLLAVRTAESLDAVLAQVQANTHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDAPLMTEYLHAAGISEAKQLVGDHWQ
IILLDTQVRGKPHGLLGDHQLAALDSALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHQGVRLIASPSTCIQFKPLCDGFALDESGPGW
RYLTLHPDGRIASQVWRLPVGQFVPDPNATGY
>A0A7L6TXY1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. RHB35-C21|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRAKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRYHPDTASEGY
>A0A644T9B8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MHSSPKYWFFIILILIQLGIAWLVLSLLKKLFPYYRNKNVVYTYWLVTGAALLVTTLGRF
SPSADLAAELMRLAFVWLIGQLAALIILPFFYGVARFVKARQPRPDDCDKNDDNNITRRD
FLRGLVAAAPVSILGVTVYGVYSGGSNIVLQRHKLNLPQLPVYLNGFKIAQLSDTHIGFY
FSLEKLEACLRTIMAEKPDMLVITGDLIDEVALAEQAMQKFAEIADQIPYGIYFCWGNHE
YFRDINKVRQALNNSPVTLLENTAVRIAKGDKPFYLAGVDYPWARNADSQIAERGQMIGK
ALATVPDNAFTVLLSHHPDFITNAFEAGIPLTLTGHTHGGQIALFGRSLLPVQYRYMRGM
YHQGDMHGYVHTGTGNWLPFRLGCPAEIAVFTLQG
>A0A645CA60|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MSYSKARFGIILLLLALLAGCAPLDLANIERDAPSASFDEPVGSESKSFSFVVFSDLHFG
RGNSGVYWKNDVFLDWLESYPTSLAFALNLGDLTSDSKEDEYLMAANFLQELEEWGVDTH
SLVGNHDIRYDGRSLFRRYIHPETARRFSYGGLSFYLLDSGNASLGRTQLKALIKQASLD
PNPKIFCSHIPFYGGPDMYYFGLSDAWERTLLVDTILDARVGLVLSGHLHLTEKLHHFTE
EHAELVCASFHGRDSLIEQTLPTWYVCSYDHISNQIAVERYQVTEEGTITTRTVALVNMP
STS
>A0A644Z9Y6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MSRSFAVFFSLYMLMYGSMHVFVYFKLRSAIGRGWKWTALFILVSLAMIVGARALWLFDF
GDAHTLRKVLSYSGYVWMAFIFMTFAWFVLIDMVRLLFYILDGLLSSRFGELLGSPKLRA
FIAVSAALSICVYGWFEALNIRTVTITIPTAKLPRGVDRVRIAQLSDVHLGWIIQEQRLA
AMLDAVKAAEPDMLVITGDLVDGDMEERQAEVALFRGLKLPHGIYAVTGNHEYHAGIGQA
LAFKEHAGLRVLRNEAVRAGGVILAGVDDRAARRYGYPVVPDASVLAGMPPNRFVVLLKH
QPYVDSDAVGLFDLQLSGHTHGGQIWPFYWATRAVYDYRPGLRAIVPPERSGQAHAASPG
RQSRIYVNNGTGTWGPPIRFLTPPEVTVIDIVRE
>A0A7U7ISY3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia enterocolitica (type O:3) str. YE12/03|TrEMBL
MESLFKLPMASEARVRVLQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGISRLPAPCVWLPGNHDFQPAMVDALANAGIAPSKHVLVGD
NWQILLLDSQVFGVPYGELSEYQLEWMERCLMAHPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLNWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGRLETEVRRLASDEFCPDMDSDGY
>A0A4R1NBJ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sodalis sp. 159R|TrEMBL
MESLLRLPVANGAIIRILQITDTHLFAGEDEALLGVNTYRSYCAVLDAIEAEQHRYDLVV
ATGDLAQDHSLEAYQLFAKGISRLPAPCVWLPGNHDFQPAMVKVLDECGISPSKHVLLGD
NWQLILLDSQVFGVPHGELSEYQLEWLDKTLRLQPERHTLLLLHHHPSASGCIWLDQHSL
RNAHMLAAVLNNFPRVKTLLCGHIHQELDLDWQGRRVLASPSTCVQFKPHCTNFTIDSVG
PGWRYLDLYPDGKLETEVHRLSGVAYLPDTDSEGY
>A0A2T3KD33|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium kishitanii|TrEMBL
MQTYSLPQTNPESVVLLQITDTHLFANGSGSLLGVATKDSFHAVLNGVDIAARHFDAIVA
TGDISQDHTPYSYQRFADGISRWSQPCFWLPGNHDFQPTMQSILPSEQIKPQQQVLVGDH
WQMILLDSQVQGVPHGELSTAQLGLLNTALARYPDRHALILLHHHPLEAGSAWLDQHQLH
NNSSLWDVIDCHPQVKAVLCGHIHQNLDRTYHGVRVLATPSTCIQFMPDSDDFALDHNNP
GWRYLELTKDGQIITSVHRISGDQFKPKLDAEGY
>A0A720ELU0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Typhi str. 404ty|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A3V8D7V9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Javiana|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A355ATD8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MAQSSDKRATVLLQLTDTHLHAEQNSRMCGVSTQETFLDVLNHIRKDSRWPPDAIVVTGD
IVQDKSRAGYQRFRETLQAFGLPVFCIPGNHDDPVLMTELLMTSPFQLCGDVKLGEWRVM
LLSTFQKGEDAGALGHDGLAVLEESLSRYSEEQVLICIHHQPLPMGSAWLDEVGLRDAQE
FLETIDRHDQVRAVLWGHVHQASDRERNNVRFLSTPSTCFQFLPDSDLFALDSRPPGMRW
LVLEPDGKITTEVDWVDAADRM
>A0A3S4W3P1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rodentibacter pneumotropicus|TrEMBL
MRNTFVYRTEKSIVKLLQITDPHLFKDEKNELLGVNTQASFAQVLKEIQQDNTEFDVILA
TGDLVQDSSDEGYQRFVKMVKPFGLPVFWIPGNHDFQPKMVENLNQPPMEKAKHILLGEH
WQVLLLDSQVYGVPHGELSQHQLGLLKATLEQYPERYTLIVFHHHLVPTNSAWLDQHNLR
NSHDLFDVLAPFKNVKAILYGHIHQQVDSRWQDYQVMATPSTCIQFKADSQYFALDKIQP
GWREIALYPDGSITTQVKRIQQTMFLPNMQEEGY
>A0A0U4IK68|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia fonticola|TrEMBL
MESLFRLPVASGAKVRILQITDTHLFAGKSETLLGINTYASYHAVLDAVIAQQRECDLIV
ATGDLAQDHSQAAYRHFADGITRLPAPCVWLPGNHDFQPAMVDALAAAGISPSKQVLLGD
NWQVLLLDSQVFGVPHGELSEYQLEWMERCLEAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHTLAAVLWRYPKVNTLLCGHIHQELDLGWHGRRLLATPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A0F7H8L8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia fonticola|TrEMBL
MESLFRLPVASGAKVRILQITDTHLFAGKHETLLGINTYASYHAVLDAVIAQQRECDLIV
ATGDLAQDHSQAAYRHFADGITRLPAPCVWLPGNHDFQPAMVDALAAAGISPSKQVLLGD
NWQVLLLDSQVFGVPHGELSEYQLEWMERCLEAYPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHTLAAMLWRYPKVNTLLCGHIHQELDLGWHGRRLLATPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A3V9FN37|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella senftenberg|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A8D9A1B1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cacopsylla melanoneura|TrEMBL
MWEWCVGTAKCRRHSEKTRTDSLCSQVAENGIHNDILRLPVPPHSTIRILVATSKDDPLY
RDIHSTCESLGYLCQLVTSLDQCVSTCCSYLPHVVLVDLRCKSFRGDQICRAIRSMKRSQ
HVILVALRKKPSLLDKSDDKEIRNILKMGFNKILYEHSSSGGACLNWSVELQSIEQNDVY
LRNLVAHNETAFCALDKSRDLVYITNQAHSIQYVNKACCSVLGYSQDELLHKFIANFHQL
GQMDQIIRQLDRGFDWEGKVSWKCKNGDTIPLHCKAQPFCAFGRDPTHFVYIQENPLDFH
NLPRGSVPSIRKGSYDLKSINSEGAQSARRQSLAKLHNLPLEAPITKVISLISAAQEHSS
DHVINILDKVIDILRTTELYSSHVKAENLRCEDPVTSDLIGALISQGPVHVSSTRRSSND
SANVKSSHPPHTHPHGGATSHTMLNMVTSPQMKELLTTSLSWDFNIFQLEHLSNKRPLVH
LGMNLLVTHYAVHKTLGIDERTLYNWLHLIEKNYHSSNTYHNSTHASDVLQAVAAFLEKE
KLNQILDELDEACCLIAAIVHDIDHPGKSSAFLCNAGNDLAILYNDISVLESHHSALTFK
LTLKDDRANIFKGLERDTYKVARQSIVDMVLATEMTKHFEHLAKFVSVFNTPTVQCHGEQ
AQDYGAQDGSNNKSPSSDPGPDDDYHVNSPEAVNLVRRMLIKCADVANPTRPLPLCVEWG
RRIAEEYFAQTDEEKALKLPVVMPMFDRVSCSIPKSQMGFVDFIINDMFEAWDAFIDMPE
MLYHLRSNYQYWKDMDEKDISSIQDIYPATGPAELIIKSPSHTQQTNKPTSSTQSNNNNN
SVAKPNNNTLSSVAKPNISTISSVGKPANVGASSSSVAKSSVLVKGVASVSSLSMSNNMN
CLPDILETKGDAAD
>A0A3D2SNY0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter ursingii|TrEMBL
MSFQVVPTSAQEYVLIQITDTHLLEQPEHEFVGMNPEQSFHEVMTHIQQHYPQADAIIHT
GDLAQAPRPKTYQRYLHFMQQLGIPFFHTPGNHDDEKYFPFHQENPQQPVLIELGNWRII
LLNTAVSNRVDGLVSTSQLEQLTDLLEQHQAHPTILACHHHPFEMHSKWIDQHKLKNSQA
VFNLLERFKQVKAILYGHVHQNSSNFWQHIECLSTPSTSVQFKPCSEQFALDAVAPGYRV
MKLKTNGTFETVVQRLEHINHLINTEISGY
>A0A826R3U1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYLHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLDWLERKLSDAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLAKFPHVKYLLCGHIHQELDLDWNGRRLMATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A826T8I6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDSHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYLHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCRWLDQHSL
RNAGELDNVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A5H7WW73|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Mikawasima|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A7G9Y9C0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methanosarcinales archaeon ANME-2c ERB4|TrEMBL
MSASEGDYVTRIVHLSDIHVSDARFLPDVAGKVVDSINEIAPDIVVVTGDLTQNGSYPEF
AGAKELIDRIDCENKVIVPGNHDSRNVGYLFFEDLFGARNSCHSYEDVTVVGVDSSQPDI
DCGHVGRDLYEWIAKSFETDGFKVFALHHHLIPVPMTGREEQIPVDSGDVLELLDRCGVD
LVLCGHRHVPYVWRLNEMFVVNAGTACSNKIKARTTQCYNLIEIDYGYLRIYRVLPGGEQ
ELVADRVMSP
>A0A5I5TSH5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella abony|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A6X6SCU0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enteritidis|TrEMBL
MFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSLRNAGELDSVL
ANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIAPGWRTLELQA
NGVLETEVHRLQDTRFRPDTASEGY
>A0KPL0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049)|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRIASQVWRLPVGQFVPDPNATGY
>A0A2K6PT62|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rhinopithecus roxellana|TrEMBL
ARIFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRN
SSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATIT
GKKDLELILHVSRKKPFLPKVNITPTPISCCSLKMLKK
>A0A6S7BWI8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pararobbsia alpina|TrEMBL
MHWIDPDCLQETRGTVTQFLVNPHGELDGFILDENQQVHFPPHMSKKVASHISIGDPVKV
RGVKPRSADIVAAVLLTTSTGVAIRDEGPNHDGGKHKKPHAEKHPMEVSGEVKLSLYGQK
GELSGALLIDGTSIRMPPDVAAELASYLEPGAHIQVWGHGVKNEYGHTIKVDDIAEWVDA
DSAEATNAREAQQSHDLAFPRESEIAREQADGVAAGGGPLVWMHIGDLHLTDAEEPNHLA
LRDIITQANNHLAGHIDFAVLPGDNADDGTPEQYAILRSELDKLRLPLHILPGDHDFKSR
SLDAFHSVLGAQQLPKAITVAGCKCLFLDYVSAGTGGPDFKLGKKQLKWLKEELESASTQ
GLETAVFAHAYPADLADAGEAKAFHKMLRDHRVLVVDMGHTHYNELGNDGKTIYAATRST
GQIEEGPAGFSILAVDKNVVSWRFKPLDQPWPIAMITSPSDCRLVTRCHSPSHVLSGRTT
VRAKAWSADGIEQVECRVGDAEWLPMTRDASTQSWTLESAIPEGTFKILVRATDLCGSSD
IDSIDIVTTTEPLQVRQAHGSDENSVGAWHEKHIFGTQLGPNRNGRKW
>A0A6S7A9A9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter deleyi|TrEMBL
MSLRQSSFFLRFLTLGALAHVYVGARLIPDAGFAGAGAATAILLLILSCILIPLGMLGRS
SVHPPWGDRIAWVGLIAMGLFSSLFVLTVLRDVLLLAAWLIDLATGVALPWIDLRRISAL
AVAALALAATLVGFYNARRRAQVVTVDVPIEGLPADLDGFTIVQISDIHVGPTIKKRYVQ
AIVDAVNAETPDVIAITGDVVDGSVEQLAAQASPLAQLRAPFGVYLVTGNHEYYSGATPW
VAEFRRMGLRVLMNEHAVIHPAGLPVVVAGVTDYSAGAFDPQQRSNPKAALAGAPADALP
KILLAHQPRSAAAAEPLGYTLQLSGHTHGGQFFPWGFFVRFQQPFTAGLHRQGRMWVYTS
RGTGYWGPPKRLGAPSEITRLRLRRAQSASSGSGPRSR
>A0A6B3PFS0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Okeania sp. SIO1F9|TrEMBL
MIFQPSVLVAQITDTHLFADSIQGKMYGVPTERSFVKVLEKLKQLQPQPDVLLLTGDLSQ
DETSQSYQRLASLLSPLNIPTYWIAGNHDNLPTMERVLSSAPISAKKSFEMGGWNFFLLN
TNVPGCVYGEISPESLEWLEYNIKMTGNKPVLIALHHPPVKINSEWMDKILLHNPENFLS
IINRYPQVKIVLSGHIHQEFAKEINGIHYLSTPSTCIQFEPGNYKFFLDKQPPGLRLLTL
YPDGNYTTKIERINYIYECDMAASGY
>A0A8F7WT98|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylovirgula sp. HY1|TrEMBL
MSLTLAHLSDAHIGPLPQPRRRELVGKRLTGYLNWTRARVHIHDMSLLAALVADMKAQRP
DHIAMTGDILNIGLKAEYPLARAWLETLGTPQEVSFVPGNHDAYVKGTLPDLAATFAPWT
KGDHGETGYPYLRRRNNVAILGLSSGVPTAPFIASGRLGRQQCEAAAKLLAEAGRAGLVR
VVLIHHPPQHDGASFGRALADAEDFEAVIRRVGAELIIHGHNHRLITRHMEGPDRPVPVV
GVASASAIRGTPEHRAGYHIFEIDGTTKEPRIKGRVRGIAPGGKGEITDLGPIML
>A0A8I1DXV7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. ACIN00229|TrEMBL
MTFQVSTLSQKDHVIIQITDTHLLEYPHLEFVGMNPEESFHAIIQQILKKHPEADAIIHT
GDLAQAPTPITYKRYIQYMQTLGLPFFQTLGNHDNVDHFPLHKENHQEPVVICLGNWRVI
LLNSAVKGQINGHLSPEQLQNLAALLEEFSDNPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLTTLAPFKNVKALICGHVHQDSLNTWQGIEFFSTPSTSVQFKPFSNEFALDQNAPGYRY
IRLKNDGSFETEVFRLENFQGLINTNISGY
>A0A807LFR4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kosakonia cowanii JCM 10956 = DSM 18146|TrEMBL
MESLLNLSLGSESRVRVLQITDSHLFAKKHETLLGVNTWESYQAVLNAIRAQQRSCDLIV
ATGDLAQDHTAAAYQHFAEGIASFDAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFVGE
QWQILLLDSQVFGVPHGELSEFQLDWLEKKLADSPQRHTLLLLHHHPLPSGCSWLDQHSL
RNAAELDNVLQRFPQVRTLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCASFTLDTIA
PGWRWLDLYPDGTLHTEVCRLAGSEFRPDTASEGY
>A0A446CMZ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter agilis|TrEMBL
MTEPQFSRQPLGARLFSFAVVADTHVNESEDTCASPFATNARANARARHVFADIARLNPA
PAFAIHLGDIVHPVPGMPSFDEAARRFKAIASQIDIPLHLVPGNHDVGDKRIDWMPADIV
CDSYLDKYREVFGPDYYAMDHGGVRFLFVNALLFNSGLETDGAQRAWIDEQIAGAGGRVF
VSLHYPPYLHDAQERGSYDNIDEPGRGWLLSRLENPKVEAIFAGHVHNFWYDVIGGAEMY
MLPSTAFLRHDYSEFYRVPPADEFGRGDVEKFGYFIVDVHERGHVAKLIRTHGAMRGETA
SGEAPARALPTVHTKTAASEGIAVELRHPWAEIVEIPCTGGVQEFGRKLARNDYPLMAMW
EMGLRTLKIPTQDLHDDKTLRRARLMTDVGHRFVLTSLGIPDTKLLDRAREHGIAIAAIE
INLNAQALQDAGPALRQLRNHTSARLIYGKIRTGADDAHFDGKHYSHFVNTGLRAAELEA
GQSALVAHLEQQHIDGITVRLDWGSDLIATHRELAERARAWGMAVNVGVKLADRLASANT
DDAAIAALVAEAFLASRASDAVTYSFDTFMDVDRGYFPRNGLINRRYDPRPAGVALAALN
AVFDIPGAASVERMDGPAGSRLCRFRTGGQEYELAYGPAPAVQRHAWAAPCKRVIDLLSQ
EAVEGEEARAEYTRQGRPGHALLLIHRA
>A0A8I0FLY0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. C1|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQCILDAIHAESTDFDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPSGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIS
PGWRTLELFADGSLHTQVCRLPGIRFHPDTASEGY
>A0A3N2E492|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. BIGb0359|TrEMBL
MESLLNLPLAGGARVRILQITDTHLFAQKHETLLGVNTWESYQAVLAAIHAQQRDCDLIV
ATGDLAQDHSAEAYQHFAESIAAFAMPCVWLPGNHDFQPAMYSALQEAGISSAKRVFIGD
HWQILLLDSQVFGVPYGELSDYQLEWLERKLADAPERNTLLLLHHHPLPSGCSWLDQHSL
RNGAALDTVLARYPRVRHMLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTIA
PGWRWLELHDDGTVTTEVCRLQSTQFSPDTASEGY
>D7XZK3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli (strain MS 115-1)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7I7A3C1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Raoultella planticola|TrEMBL
MESLLNLPLAGETRVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRPCDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLLESGISPAKRVLLGE
HWQILLLDSQVFGVPHGELSDFQLEWLEQKLAEEPERHTLLLLHHHPLPSGCSWLDQHSL
RNAGALDRALSAFPRVKHLLCGHIHQELDLNWNGRRMMATPSTCVQFKPHCANFTLDTLS
PGWRWLEVHADGTLTTEVCRLNGVKFHPDIASEGY
>B3H312|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinobacillus pleuropneumoniae serotype 7 (strain AP76)|TrEMBL
MSSFYSLGKKEPVVRLLQITDPHLFTSESETLLGVNTTDSFQAILDQIRQSEFEYDLVLA
TGDLIQDHNPEAYHRFAQMVKPLAKPIFWLEGNHDLQPHMGLYLAKYPHISPAKHILAGE
KWQIILLNSQIAGAASGHLSFGQLSWLDKKLAEYPDRYSLVVLHHNILSTRSAWLDQHCL
NNSEQLAEVLRHYPNVRAILHGHIHQEVDDIWQNYRIFATPSTCIQFKPNCDDFTLDLLP
QGWRELNLFDDGHIETQVKRLNSNEFLPDFKSKGY
>B2PX91|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia stuartii ATCC 25827|TrEMBL
MEQGKLLDSQLEVTARNAKVVRILQVTDTHLFADTANTLLGINTHKSYHAVLDAILEQNL
PIDLIVATGDLVQDQSPEAYQHFAKGIERLPAPCVWLPGNHDYQPAMVSSLKLAGISSAK
EILIGDEWQILMLDSQLQDVPHGELSEQQLEWMKSCLDKRPQRTTLVMLHHHPLPSGCTW
LDQHSLRNSHILADYLKGYPQVKVMLCGHIHQEMDEYWHGIRLLATPSTCVQFKPHCTNF
ALDTVAPGWRYLELSINEKGERHISTQVCRLNTKEFSPDFDSDGY
>A0A5J4P935|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MNMIRFLQFSDIHFLFCEDTEDEYAQMRIRFIEGLENVKKQLGVVDYVLICGDIACKGQK
NEFNKAKIFIESVSKAL
>A0A195F2E0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trachymyrmex septentrionalis|TrEMBL
MKDQIPYHKTVKYVEVSPRARRRAIYKLLESIYLDKEELKGPQDFSNYLLTTDVPNIIRI
LLVFSNDDQQMDLLANTARRLGWSVSVAKDAEKALELFQNRAHELVIIDHRAHHADEGDA
ICRAIRSSPVYHSSVIIALVKKSYFMLDEKDHIVALNLLETGFTRTLMECSHEGILINEL
VEIYTSSILPRTQLAAAHALYLALDRCRDMVHVTNDKNIVQFLNKVSEKLLGYKVEEMMG
RNLSEIVYYENFSLMEQQLSKGREFEGNMNCKRKNNQMITINCRIIPFCITLKKPSHYIY
VYDTTYLSENSAPISPISSPLHPPLKTNMTNTRKSSDVRSGSISEDKGRRRSSLQKLHTL
QLEAPITKVITLLSNAVTDTTNPETAAQIEKAIDILKTTELYVPHLKEDRAMCSDPVATD
LVGALLASPRTAWESRRSSSDSARLSTIKAITSPANLRMQVKNFRGPQEITEILDNSLDW
DFEIFKLEVLTEGRPLVFLGLTIMNLYHAPATLHCDERTLQNWLAIIEHNYNAENSYHNS
THAADVLQATARFMQSKRLKEILEPLDEVAALVAAAAHDIDHPGRSSQFLCNANSRLAIL
YNDLSVLESHHAALTFKLSLSDDSVNIFKNMDRDAYKLLRQNVIDMILATEMTKHFEHLA
KFMNVCSARIGDEETYSNSLDMTVVLQPDNVILVKRMMIKCADVSNPTRPLKRCVEWARR
IAEEYFNQTDEEKKLKLPVVMPMFDRMTCSIPKSQIGFVDYIINDMIEAWDVFIDMPEIV
GYMRHNYEKWKEYIEQGISTLQDVEKLQQHPEMQILRLS
>A0A7W3FTS5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sp. TW 6|TrEMBL
METELPQAPDGSVRLLQITDTHLFASAEGRLLAVPTAQSLAAVLERVQANEHPFELILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGDHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHHGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRVASQVWRLPLGQFVPDPNATGY
>A0A7X4LIK3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. CAIM 722|TrEMBL
MNVSSGLENLDSVKLLQITDTHLFAPDDGGLLGVNTADSFTAVVNEIQHNKVEYDAILAT
GDISQDHSLESYQRFAEGISCLSKPCFWLPGNHDFKPNMGGVLPSPQIHDEVQILLGKHW
QVIMLDSQVSGVPHGYLNDQQLELLEKALSQYPERWSLVVLHHHPVLVDSEWLDQHTLKA
SEAFWSVVSRHTNVKAVLCGHIHQELDLIHQGVRVLATPSTCVQFKPKSNEFSVDKRSPG
WRELELMADGSITTKVKRLANSMYLPDYNANGY
>A0A7H0MI28|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kosakonia sp. SMBL-WEM22|TrEMBL
MESLLNLSLGSESRVRVLQITDSHLFAKKHETLLGVNTWESYQAVLNAIRAQQRACDLIV
ATGDLAQDHTAAAYQHFAEGIASFDAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLDWLEKKLADSPQRHTLLLLHHHPLPSGCSWLDQHSL
RNAAELDNVLQRFPQVRTLLCGHIHQELDLNWNGRRLLATPSTCVQFKPHCASFTLDTIA
PGWRWLDLYPDGTLHTEVCRLAGSEFRPDTASEGY
>I2NI25|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus paraphrohaemolyticus HK411|TrEMBL
MNTFYPLEPKTSVIKLLQITDPHLFSDTTKDLLGVNTYASFQAVLDEIQAEMQTQSGNFD
AILATGDLIQDHEFEGYLHFAEMIQPLAKPLFWLEGNHDQQPQMSLQLGKFDYIRPEKQI
FAGEHWQILMLNSQVTSAPNGFLSKGQLAWLNQKLSENPERFTLVVLHHNILFTNSAWLD
QHSLKNRDALAEILALYPNVKAILHGHIHQEVDAIWNGIRILSTPSTCIQFKPNCDDFTL
DNLPQGWRELSLFEDGRIETEVKRLKTQAFLPNFDSQGY
>A0A7Z1S0G5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cyclitrophicus|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVNQGFDYEAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVDHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLIEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPNGQFLPDFEAGGY
>A0A5H7IC60|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Mapo|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2J8S124|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pongo abelii|TrEMBL
MPLVDFFCETCSKPWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISTTFLGSVHGPG
DSRRPLRGCHPRCGSPWGLQPVPHQHQFGAGAHVQR
>A0A091NM91|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Apaloderma vittatum|TrEMBL
FDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSS
LPSEQHGDDLIVTPFAQVLASLRSVRNNFTLL
>A0A8I1K8X6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas psychrophila|TrEMBL
MPNVSTLTTEDPVLLVQLSDSHLFADADGSLLGLKTAQSLQQVIDLVRTEHPRVDGVLAT
GDLTQDGSVEAYQHFRRMTAQLAPFARWLPGNHDQVPQMREAAVQSRLLEPVVDVGNWRI
TLLNSAVPHSTPGYLEEDQLQLLAQSLSEAPERHHLVCLHHHPVSVGCQWLEPIGLRNAK
DFWSVLDRYPHARAVLWGHVHQAFDQQRNEVRLLASPSTCIQFAVASPEFKVSNEAPGYR
WLRLQPDGTLQTGVSRLADFTFEPDYSANNY
>A0A3M2HXM8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas zhaodongensis|TrEMBL
MAAAPLTAEKDSVLLVQLTDSHLFAEAGGKLLGMDTAESLQRVVDLVLDEQADVDLVLAT
GDLSQDGSLDSYKRFRALSERIDAPARWCPGNHDELDMMRQAASGSDLMLPVLDIGAWRV
VMLDTLVPGSVFGMLRDEQLALLEQTLAQAPEQPHLVCLHHHPVSIGSRWMDSIGLRNRD
ALFEILDRFKCVKALLWGHIHQEFDGWRSDVRLLATPSTGVQFAPGSEDFQVDTRAPGYR
WLRLYANGELETGVSRVVGMDFVVDYSVKGY
>A0A1S2CRU9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sobria|TrEMBL
METDLPQAQDGSLRLLQITDTHLFASQEGRLLAVRTAESLAAVLEQVQANPHPYDVILAT
GDLSQDHSPESYQRFASMMAPLSRPIYWLPGNHDDSPLMTEYLHAAGISEAKQLVGDHWQ
VILLDTQVRGKPHGVLGDHQLAALDRALRQYPDRHALITLHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHHGVRLIASPSTCIQFKPLCDGFALDESGPGW
RYLTLYPDGRVASEVWRLPVGQFVPDPNATGY
>A0A8C8YG95|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Prolemur simus|TrEMBL
LVLLPPLSSPGSREKLKQASLSSSVFKQLFFFQVAVAEVQFGPMRFHQDQLQVLLVFAKE
DNQCNGFCRACEKAGFKCTVTREAQAVLACFLDKHHDIIIIDHRNPRQLDAEALCRSIRS
SELSENTVIVGVVPPLFNPKISLFCLACNSIFTALEKSQEAIEITNEDHIIQYANPAFET
TMGYQAGELIGKELGEMPINEKKADLLDTINSCIKIGKEWQGVYYAKKKNGDNVQQNVKI
IPVLGQGGKIRHYVSIIRVCSSNNKAEKISECVQSDTNTDNQTGKHKDRRKGSLDVRAVA
SRSGETSSQRRHSSMARIHSMTIEAPITKVINIISAAQESSPMPVTEALDRVLEILRTTE
LYSPQFDAKDGDPHASDLVGALVSDGLRRLSGNEYVLSTKSSQQVSSNIITPISLHDVPP
RIARAMENEEYWDFDIFELEAATHNRPLIYLGLKMFARFGICEFLNCSESTLRSWLQIIE
ANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPVDKVAALIAATIHDVDHPGRTSS
FLCNAGSELAILYNDIAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQGIIDMVL
ATEMTKHFEHVNKFVNSINKPLAALEESEETEKNQEAINSMLRTPENRTLIKRMLIKCAD
VSNPCRPLESCIEWAARISEEYFSQTDEEKQQDLPVVMPVFDRNTCSIPKSQISFIDYFI
TDMFDAWDAFVDLPDLMQHLDNNFKYWKGLDERKFRSLRPPPE
>A0A7G9YFR0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methanosarcinales archaeon ANME-2c ERB4|TrEMBL
MNFVHASDFHLGYVQYGLPERFKDFARAFDRVVDYTIQSNAEFLLIAGDLFHKRNINAPT
YMQAFKILTKLADRGIPVYAIEGNHDLAYHRDVNGWMQILDAQGMLRLIRIKPMEQVGQH
EIKLMGDFVDINGVRIFGVKYLGSQTRNLIPEIAEEIKTINDRCGTPDYTILMMHFGMEG
VISASGIGELSYNSLIPLRDAVDYLALGHYHIQYEYDGWIFNGGSCETVSMSEYRKPKGF
YHVVDGKPSFQKAAPRHIERFGIDTSGIRSIRDMYSTVRSVLAGAANRDRDTKPIVDISL
HGDLRFPRTDISVEKIKEIVSEHLDPLWVNIKIIDTKDPAGIVDDRDISRTEIERSVIEE
MVKNTQYRRHLTDVTDMVIEAKQLAVSKTDPQIILEHLQNSYSVIKSENKEQTDLPFSRG
GRGNRGSSGGEDRGGGTNVD
>A0A7L6YL30|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. RHB20-C16|TrEMBL
MESLLNLSLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEGQEYDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKCVMVGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLAAAPERHTLLLLHHHPMPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDSIG
PGWRTLELFADGTLKTDVCRLQGTEFRPDTASEGY
>A0A7T3AV55|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas stutzeri|TrEMBL
MPGAPLTAVEDSVLLVQLTDSHLFAEADGKLLGMNTCDSLKRVVELAIEEQPRIDLILAT
GDLSQDGSVASYQRFRQLAGRIEAPARWCPGNHDDLGAMREATRGSELMEPVLEIGGWRV
VMLDTLVAGSVYGMLRGDQLELLHRALGEAPERHHLVCLHHHPVSIGSRWMDSIGLRNPE
ALFEVLDRHDNVRALLWGHIHQAFDQSRNGVRLLATPSTGVQFTPQSEDFQVDSAAPGYR
WLRLYADGRLETAVSRVSGIAFEVDYSVKGY
>A0A1Y6MM49|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium malacitanum|TrEMBL
MQTYSLPQSNPDSVVLLQITDTHLFANGSGSLLGVATKDSFHAVLNGVDMAARHFDAIVA
TGDISQDHTPYSYQRFADGISRWSQPCFWLPGNHDFQPTMQSILPSEQIKPHQQVLVGEH
WQMILLDSQVQGVPHGEVSATQLALLETALARYPDRYALILLHHHPLEAGSAWLDQHQLH
NNHQLWNVIDKYPQVKAVLCGHIHQNLDRIYHGVRVLATPSTCIQFMPDSDDFALDDNNP
GWRYLELTRDGKIITSVHRVDGDQFKPKLDAEGY
>A0A7H1C488|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mannheimia bovis|TrEMBL
MSEQFELPKNGTVRLLQITDPHLFSHTEETLLNVKTVKSFSAVIEQIQKQIEQTQQGFDL
VLSTGDLIQDHNIAGYHYFAQLTEPLKTPVVWLEGNHDVQPNMAEILGEYSHILPQKQIL
IGEKWQLLLLNTQVAGMPYGELCYHQLKWLEEKLNEYSERFTLIALHHNILPTNSAWLDQ
HSLKNSDELAKILQPFDNIKGIVHGHIHQQVDDVWNGIPIYATPSTCIQFKPNCDQFTLD
LLPQGWREIILHENGVIETTVKRLNCNDFLPNLNALGY
>A0A7T4UQ43|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Spongiibacter nanhainus|TrEMBL
MGQRSIDNSASDTAVSSGGRAYTVVQISDCHLGSEPGEALLGMDADHSLAAVVSLLQHEQ
AHIDLLVVSGDMAADASTQAYRRLFPLLNGVAERMVWLPGNHDDIDTLRQIVASDVLANR
VDLGGWQLLMLDSAVPDQVGGQLRGDQLALLADLEPGRPAVVFLHHHLQPIGCQWLDEQR
VSNADAFFSQLPDCVKAVICGHVHQASENEHRGVSLLTTPSTCIQFKPGSEDFALDDLSP
GYRWLRLHPGGELETGVSRVSGVEFQVDYAANGYQ
>A0A6J5FDJ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia caffeinilytica|TrEMBL
MLLAQISDLHIKRPGALAYRRVDTGAYLARTVAALNALEPRPDAVIMTGDLVDQGDPEQY
AHLKTLLAPLEIPYFLMVGNHDERTALRAAFPERAELHSGGEFVHYAVDVGPLRVIALDS
MVPGESAGNLCDARLAWLENQLDAARGKPTVVALHHPPFVCGIGHMDELRLDPAAADKLA
ALIARYPNVERVICGHVHRPMFVRFGGTIACAVPAPAHQVGLDLRDDAPSAFVMEPPAYA
LHRYDPATGIVTHHAYVDAADGPYPFYEPEGDLID
>A0A6J2XMU9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sitophilus oryzae|TrEMBL
MGCFPSTLLEQIQKGSSASLDKADKSVAKTKFLEVNSVSTAGAATTTTIHINSVPRGSKR
GKLLGMPFNPFRRDIGRGVLHHRKSSLALTPEEEPFDINRGPNELKYGLIIPNIKHQLKL
LLVFAQLDPVSETFTKAAEKLGFEVTLCHTDISALEEYQTKSHDLVIVDNRITKAFDNDL
LCRSIRNTRGSQHTVMIAVVKKSAFERDDITITSLLESGFNRCLIETTNLLTCVNEMILL
KHSDIRIMAQHATCQALYTALDKCKDLVIVTDDTYKFQYMNTACERQLGLRQEDTLGKTL
QEQLVYDTVQINTMGSSLLRAREWSGPMTLKRKSTQDPIVTSCKAVPFSCAGRMPTHFIL
VFDTNSIDPNMLSQSRGSIHSIRRGSTDVRSVGSDYLRRTSLAKLNALPLEAPITKVIGL
IDQIRESLGSNPQAIQLIDRVEDILKSSELYVSHVKEDSKVKADEPVVSDLITALLSKTP
QPTLSASSRRSSNDSSVFRPSRTGLIKAPAAIRDLLETSLTWEFDIFKLEDLSRRRPLQH
LGMNLFNHFDVCGSLNCDEKTLSNWLTVIEANYHIENSYHNSSHAADVMQATAGFLEKER
MKSIMEPLDEATSLIAAAAHDLDHPGKSSAFLSNSNNPLAILYNDVTVLESHHSALMFKL
TLGDERVNIFKNLDRDTYKLARHNVIDMILATEMTKHFEHLAKFVNVFCPRSSIGSDMDQ
PDDYNALLSPENTTLVKRMMIKCADVSNPTRPLRICVEWARRIAEEYFQQTDDEKMRGLP
VVMPMFDRATCSIPKSQIGFVDYIINDMFEAWNAFIDMPELLTYMRQNYIRWKEFDEQGH
TTLSDIQKLQATVLSPSVSSAIKSD
>X1WF25|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Danio rerio|TrEMBL
MGACCFERKEQKKAGKVNCWEKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQNDVE
IPSPTPKAREKKKKQQLMTQISGVKKVSHGPSLNCGIARFGVKTDKEDLLSKELEDLNRW
GLNIFTVSEYSNNRPLTCIMYAIFQERDLLKTFKIPTDTFVTYMMTLEDHYHQDVAYHNS
LHAADVAQSTHILLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALM
YNDESVLENHHLAVGFKL
>A0A811XIN0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter europaeus|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRAKYLLCGHIHQELDLNWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A8I0VD55|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas mendocina|TrEMBL
MPSLPTPSADSSVLLVQLSDSHLFAEADGKLLGMDTRDSLQRVIERVQQEQAQIDLILAT
GDLSQDGSQASYQRFRQLTAAIGAPARWLAGNHDETPPMQAACQGSDLLEPVIDLGAWRI
VMLDSSIPGAVPGFLADSQLELLERALSEAPQRHHLICLHHHPVPIGCKWMAPIGLRNPD
ALFAVLDRHPQARALLWGHVHQEFDQQRGNLRLLASPSTCVQFAPGSEEFQVGSEAPGYR
WLRLHADGTLETGVSRVTGITFEIDYSVKGY
>M7RJE9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Dublin str. UC16|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A1JQU1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)|TrEMBL
MESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFASGISRLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLVGD
NWQILLLDSQVFGVPYGELSEYQLEWMERCLMAHPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGRLETEVRRLASDEFCPDMDSDGY
>A0A5E4Z4U2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea pneumonica|TrEMBL
MSQTSQASRAPSEATDGPAHRHGKSSRRTLPARPRWLMLAIIALLHAYIGWRLLTPLPVA
IGWKVAGALWLVASTILIPLGLMSRALQREPLATLLNWTGMMAVGVFSSLFVLTLLRDVV
LGVAMAFSVLDAQLVTRSAVIVLIMTAAATVLGFYNARRLARVVDVDIPIANLPPELKGF
TIVQLSDIHVSSTIRRRYIEAIVDAANELKPDLIAITGDLVDGSVPALRDHIAPLGRLTS
RHGTYVCTGNHEYYSGAPAWVEELRRLGLTVLENQHVVLDHEGAALTVAGVTDFGAHHFD
EEKRSDPQAAAAGSPDGVPRVLLAHQPRSAPAAAEAGFDLQLSGHTHGGQFWPWMYFVPL
QQPFVHGLHRLDRLAVYVSRGTGYWGPPKRFGAPSEITRIRLMPGKA
>A0A0M0TBZ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus sp. GDc328|TrEMBL
MESLLEVPVAEGATARILQITDTHLFANKGDSLLGVNTYRSYHAVLDRILQQNLDIDLIV
ATGDLVQDQTINAYQHFAEGIARLSAPCVWLPGNHDYQPAMVDTLAAAGISPSKQIVIGQ
HWQLIMLDSQVQGVPHGELTDYQLEWMKKCLDEHSDRHTIIMLHHHPIPSGCTWLDQHSL
RNAPELSACLKGKTQVKAMLCGHIHQEVDEMWNGIRVMATPSTCVQFKPHCTNFMLDTVA
PGWRYLELSVAGNNKDAKLQTQVHRLKSNEFCPDLNSDGY
>A0A2H6ANS9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR37|TrEMBL
MKIVHISDLHLTSPTFVPEWEQNVINTLNSIKPDILVVTGDLTDWGYEYEYRVVSGFFEK
IKANRLIVVPGNHDSRNEGYLIFEEIFGTRYPYYEDNEVVILGIDSSEPDIDDGHIGREN
YDIIKDRFWAKDKIKILALHHHLIPIPGTGRERHIPVDAGDVLRLCTELEINFIFSGHKH
QPWIWKLEKSYFVTAGTATTRRLKGRSFPSFNILDISQEKLTLYEVNVAQKSTKQIKVIL
RSEFNEKTTRGN
>A0A2H6AJ28|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR37|TrEMBL
MLFLKVPMLLAKPSFYPLLLLLLTLVLFKPNICFGGKKDALKIWVISDIQPRDRDQREEF
RRAILDINKNVPDIDFVIVAGDIVDGAQEEDFNWYLSLKKLSYIKEWYEIAGNHDLKLNR
GEGYREKIRKDLYYSITKGNILFLFMSDELRGKPTEISNKTFLWWKNQVTGNQDKIIVVV
THAPLEGSGIPFSSLHDRQILDSKRFVEVLKNYRVDLWFSGHIHLPHSFTNNIVKKGEYG
GTVFVNASSIRTELLGLKPSESRIVTFYCDSNRVTIRSRNHSKEGFNKALDVEFRLPVKY
DCN
>A0A5Y2FGD8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella newport|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A7Y8DJE5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. IPO3778|TrEMBL
MPSVSALNPDASALLVQLSDSHLFAEADGGLLGMKTRDSLQRVIETVLAQQPQIDLVLAT
GDLSQDGTLESYQAFRDMTRQIHAPARWIPGNHDEPQVMQQAAINSALLEPVVDVGNWRI
TLLDSAVPGSVPGYLQDQQLQLLAQSLSEAPTRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRGVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLDTGVERVQGFVFQVDYGSSGY
>A0A7U9WUB8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lachnospiraceae bacterium|TrEMBL
MCRIGVLHLSDLHLTSNQNELKSRDYRNLKKEIIDAVNNIKSKSKIDVVAVTGDIINKGR
TDDYSLAKRFFEDISKETSIPLNRFVFAAGNHDAPRDKFIKTMKISEMEEYSSFKNHLLG
RFSNFCKFYKDLTGDESRISDESYGIKDFEIDKKIIRFIVINSSVCTNDKQDFMNLEISK
YQLESLENEMRNAKSNPILTIALMHHPIQWLEYNEQEQLLEYFEDEFDVNILLHGHTHEG
RVYGNMDIDRTLINFVTGIGYDQSEKEDYKKLKYRMAFYNFDTNRNVIEGNLLVTNEKLT
FVPDTSKYRKINVDGYFSINYPLNDIKNLHVYNQYINSYDSKNVRINRELVDKVNILEKM
IYDGKKYLTNHAYIRFNTVKKKYELKFEKKYEIIGDETSWYSGQFYGNKYKDNPKKSKEF
YDKNIIKWEDLNFKAYVKVLNSENKITQKKVEVLVECVAESSNYKTFNIKYINKRVETNL
DVHHGDFIELEYSYEIPEHYWGSYLNRTISYFREIGDINISCDDNQKLINQVTNQDLFLT
KPPKTQISNSEDFVLQKNGSYLIKLPNESGKYTIHWNAKKLFGEEAENTAPGKDECQITN
T
>A0A5Q2KC88|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cancerogenus|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRRCDLIV
ATGDLAQDQSSAAYQHFSEGIASFSAPCVWLPGNHDFQPAMYSSLQEAGISPAKCVFLGE
QWQVLLLDSQVFGVPHGELSDFQLDWLESKLAAEPARHTLLLLHHHPMPAGCSWLDQHSL
RNSAALDRVLVKFPHVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCDSFTLDTIA
PGWRWLELHADGTLTTEVCRLSGAEFRPDTASEGY
>A0A7U9SWZ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lachnospiraceae bacterium|TrEMBL
MRYYIADPHFFHGNLNTKMDCRGFADAEEMNRYMLQKWNAKVRKNDEVVILGDLSWGKAE
ETNELLGKLNGRLYLIQGNHDRFLKNKDYNASRFVWIKPYEELQDNKRKVILCHYPIMCY
NGQYRLDGNGNPKVYMLYGHVHDTYDQRLLEQFQKITRSSIRENPDGERRAIPSNMINCF
CMYSDYTPLTLDEWIICDRKRREKLCVDGSMWTRGQPGKLNG
>A0A6F8VX76|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio alginolyticus|TrEMBL
MQSSSDSIKLLQITDTHLFAADEGSLLSVKTADSFNAVVADVLRRNVTFDYILATGDISQ
DHSAESYQRFAEGIEPLEKDCFWLPGNHDYKPNMGSVLPSQQIKAAEHVLLGAHWQLVLL
DSQVVGVPHGRLSDQQLALLEEKLAEHPERHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFDNVKGILCGHVHQDMNVLHNGIRVMATPSTCVQFKPNSDDFALDTTSPGWRELQ
LHACGEITTQVGRLPDGQFQPDFSSNGY
>A0A8C8R819|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pelusios castaneus|TrEMBL
MTAKESSKELAAPDSDIYIKTFKEQMHLELELPKLPGNRPTSPKISPRSSPRNSPCFFRK
LLVNKSIRQRRRFTVAHTCFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFL
YRSDSDYDLSPKTMSRNSSIPSEQHGDDLIVTPFAQVLASLRSVRNNFTVLTNLQGASNK
>A0A812BKR5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sepia pharaonis|TrEMBL
MRYKLSASMALFTALEYASDAIEIVNADHEIQYINRAYERLSGYATDEILGKNAKEFPRS
EKVKPEHMDIINNHLVKDKLWEGMHYMRRKSGGSIPHHCQIVPVLGPRGFFCFYLTTYLY
LSLPHFISLFISFYLSLSLFISLTVSLSLSLSLFLSTYLSQSLYISLSQSLYISLSQSLY
ISLSLNIISLSLSLSLSYLSLSQYLYISLSLNISTYLSLSISHISLSSLHISLSVSLHIS
LSQYLYISLSLSISLHISLSLNISTYLSLSISLHISLSLSISLHISLSLNISTHLSLNIS
THLSQYLYTSLSLSLSQYLYIYLSLSQSLYISLSLSKSFSLSIQIFLSQPL
>A0A7D5D4H0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas eucalypticola|TrEMBL
MPSAPLPTADTPVLLVQISDSHLFAEAHGTLLGLNTADSLARVVEKVLAEQPHIDLVVAS
GDLSQDGSVESYRRFEQLTAPINAPKRWFAGNHDEPLPMEQAATGQDYLSPVVDLGNWRI
TLLDSSVPGSVPGYLADDQLQLLAQALSEAPQRHHLICFHHHPVSIDCKWMEPIGLRNPH
ALFEVLDRFPQARAVLWGHIHQDFERERNGVRLIASPSTCIQFKPGSEDFALDELAPGYR
WLRLLPDGRIETEVSRVEGFEFTPDMGADGY
>A0A679K637|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium bullatum|TrEMBL
MIDRPALTRRETLAGAAVLALAPSAARSSERATGSVYEVVPGGRAGIPDVAVSNGRDVVR
TDGQGRYALDVSDGDIVFVVKPAGFALPRDENNIPRFSYIHQPQGTPPDLSLRYRGIDPT
GPLPASIDFALTREPEPDAFDVILFTDPQPESPVELGHVRDTAVTRVLGTKAAFGMTTGD
ILFDDLSFYGRSNRIMGRIGIPWFHIGGNHDLNFEAPDARYSRETYKRVYGAPYYAFHHG
KALFLMLDTVHYLGAASGKGDGVGRYEGRIGERQMTFIANMLSMTPKETLVVIAMHIPLV
TDLDPADPRQNVMDRERLLDLLGDRPVLSLAGHTHTTEHHYPRAGASGSHHHHVLTAVSG
SWWSGPSARTGIPSADSRDGTPNGFHVLSIDGADYTTRYQPAQGEPEERMRIVLESQYRG
GAGEVLRDYRPMQTLRSPVPRESVGATNLVVNVFDGGPRTSVRYRIDDGPAVEMVRTRRP
DPFVAEVFLRYPEAKKPWVKAEPSSHIWVARLGGDIPAGSHRITVEVRDEYGRPFSSAMV
LEVTGEDGPSRG
>A0A679JJN0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium bullatum|TrEMBL
MRLFPISDLHLERRRPETIARPDAPFDVLVCPGDLYEGRPEAGLAALRGIAQGRPIVLVP
GNHEHYAPTGDSRTAPALIAALEAEVARINDEGEGAPVHLLNHGACVVLDGVRFVGTTLW
SDWALAGRWLDETVPDRPADPVAYAAARMTHPVTGSREFRGSIRKGDGSVWSPADAMAAH
LAQKAELAAALAAPHPGPTVVVTHHPASPLAADAFRAIPGVPWWVPAFYATTALDDLPEA
SRPDLWVSGHFHAGHDLRIGRTRWIANPVEGGTYSAERFVEVG
>A0A828PYT7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinobacillus pleuropneumoniae serovar 6 str. Femo|TrEMBL
MSSFYSLGKKEPVVRLLQITDPHLFTSESETLLGVNTTDSFQAILDQIRQSEFEYDLVLA
TGDLIQDHNPEAYHRFAQMVKPLAKPIFWLEGNHDLQPHMGLYLAKYPHISPAKHILAGE
KWQIILLNSQIAGAASGHLSFGQLSWLDKKLAEYPDRYSLVVLHHNILSTRSAWLDQHCL
NNSEQLAEVLRHYPNVRAILHGHIHQEVDDIWQNYRIFATPSTCIQFKPNCDDFTLDLLP
QGWRELNLFDDGHIETQVKRLNSNEFLPDFKSKGY
>A0A829AM51|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli KTE119|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>C5B6Y1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Edwardsiella ictaluri (strain 93-146)|TrEMBL
MESLFHLAVASGAPVRLLQITDTHLFAGQQETLLGVNTYRSYQAVLAAIRAEAHPFDLIV
ATGDLAQDHSAAAYRHFAAGVAELHRPCLWLPGNHDFQPAMVDALAQAGVHANKRALLGE
CWQIVLLDSQVVGVPHGELSDYQLEWLELTLASEPQRHTMLLLHHHPQPSGCTWLDQHSL
RNAHALDEILRRYPQVNTLVCGHIHQELDLDWNGRRLLATPSTCVQFKPLCTNFTIDTIS
PGWRYLTLYPDGRVTTAVHRLASSEFRPDLDADGY
>A0A6N3QYV9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella flexneri CCH060|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A4W5NK06|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hucho hucho|TrEMBL
MAGNCECEHLSSNLPSLSISLRRFDVDNGSSPGRIPLDPMVSPESRLILQANFVHSQWRE
SFLYRSDSDYDLSPNSSINSDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQQDRASNN
WSPLCCYNSLHSSGKAFH
>A0A4W5RJ77|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hucho hucho|TrEMBL
MPTVKRSPLGGVAPHNPRAALSDQQYEQLATDTLEELDWCLDQLETIQTHRSVSDMASNK
FKRMLNRELSHLSEMSRSGNQVSEYISSTFMGEYTYLDMPVVTCTYLNLPVR
>A0A4W5RJ77|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|huchen|TrEMBL
MPTVKRSPLGGVAPHNPRAALSDQQYEQLATDTLEELDWCLDQLETIQTHRSVSDMASNK
FKRMLNRELSHLSEMSRSGNQVSEYISSTFMGEYTYLDMPVVTCTYLNLPVR
>A0A7U9G8B1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli H299|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A6I8VRY5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila pseudoobscura pseudoobscura|TrEMBL
MGCSPSTLPNSASANANANTNAGPTAANSVPLSLDATEKDGSRLFCIKLRRSRLRRCSCG
GVALQQGDGNGNGSTAGSATCGSGTGDNLCHQVLLNPLQAKNEADYEKLSTGKKDSIVTV
AALGNFTHSVVRRATGSTGTGTSGTSSSGGGGNNRPGHRKSSLALALTPEDDPMDVYQRN
LMDLKYPTVLPPNPQLKALLVFHKSDSICEAVASACQRHQLDVTLVKSKEEALDTLQKSY
ATAQCYHLIIIDARSSKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDA
GVNRCVAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQ
YANRATERLLNMRLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMH
VRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASD
GLRRTSLAKLTSLPLEAPITKENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIAT
DLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKANPIIMELLEESLSWDFDI
FKLEEITDYHPLLYLGMEMFRRFDVFATLNIEENVCKAWLAVIEAHYHKSNTYHNSTHAA
DVMQATGAFITQLTNKDMMVMDRMEEAMALIAAAAHDIDHPGRSSAFLCNSNSALAILYN
DLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKF
VSVFGGEEPREHNPQSDEETAILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTD
EEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQW
KKYDEQGVNTLADVMAMQPPMVKLANSK
>A0A7Y0ZB60|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. WS 5503|TrEMBL
MPSVSAVNPDAVLLVQLSDSHLFADADATLLGMNTRESLQRVVELVRAQQPAIDLILATG
DLSQDGTLASYQQFRDLTAPLGAPARWIPGNHDEPQVMAQAAMHSDLLEPVVDIGNWRIT
LLDSAVPGSVPGYLQDEQLQRLAQALSEAPDRHHLVCFHHHPVPIGCAWMEPIGLRNPEA
LFAVLERFPQTKALLWGHVHQEIDGERNGVRLLASPSTCIQFAPGSEDFQVSEQAPGYRW
LRLHGDGRLETGVERLVGFAFTVDYGSNGY
>A0A7I9ZYU7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacteroides acidifaciens|TrEMBL
MKKNLLLIIAILFVFSAQAQNTLKLMTYNIKNANGMDDVCNFQRIANVINNASPDVVAIQ
EVDSMTKRSGQKYVLGEIAGRTQMHAYFAPAIDFDGGKYGIGLLTRQVPVRLQTIPLPGR
EEERALVLAEFEDYIYCCTHMSLTEEDRMESLKIVKSFTTPYKKPLFLAGDMNAEPESDF
IKELQKDFQLLSNPKQHTYPAPEPKETIDYIAALKSNANGFALISARVLNEPVASDHRPI
LVELRTAEKANKIFRTKPYLQNPVGNGITVMWETTVPAYCWVEYGTDTTQLKRARTIVDG
QVVCNNYLHKIRIDGLQPGQKYYYRVCSQEMLLYQAYKKVFGNTAQSSFSEFTLPTTDTD
SFTAVVFNDLHQHTQTFRALCKQIQNVDYDFVVFNGDCVDDPVDHNQATAFISELTEGVH
GDRIPTFFMRGNHEIRNAYSIGLRDHYDYVGDKTYGSFNWGDTRIVMLDCGEDKLDSHWV
YYGLNDFTQLRNEQVDFLKKELSAKEFKKAKKRILIHHIPLYGNDGVNLCADLWTNLLEK
APFNVSLNAHTHKYAFHPKGELGNNYPVVIGGGYKMDGATVMILEKKKNDLKIKVLNVKG
EILLDITV
>A0A329WBA9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus sp. S8-52|TrEMBL
MESQFELPVVEGTTAKILQITDTHLFASKEDTLLGINTYRSYQAVLDAILKQNADIGLIV
ATGDLVQDQSLEAYRHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGK
HWQLLMLDSQVQGVPHGELSEYQLEWMKKCLDRYPERYAVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQGYSRVKAMLCGHIHQEMDLDWNGIRMMATPSTCLQFKPHCTNFMLDTVA
PGWRYLELSVADNGEFGLTTQVYRLASNEFCPDLDSDGY
>I3NG07|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ictidomys tridecemlineatus|TrEMBL
MSIIMKPRSRSTSSLRTTEAVCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRA
PSKRSPMCNQPSINKATITEEAYQKLASETLKELDWCLDQLETLQTRHSVSEMASNKFKR
MLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDL
EILAAIFASAIQDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDI
FQNLTKKQRQSLRKXXKKNVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEEGRQGQ
TEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVG
EEESQPEAPVIDDCSPDT
>A0A2S6U3L6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alphaproteobacteria bacterium MarineAlpha4_Bin1|TrEMBL
MTISGKHLLTFAVIADTHMNQSEDYSSSPYPANALANARTRRVVAELNQRDLAFIVHLGD
LVNPVPELPTYEDAANHFKHQMAALKAPLYLVPGNHDVGDKPVSWMPAGRVNDDHLALYE
SHFGRHYFTFDHGDLHFVIVNAQIVNSGLAAEAAQRDWLEADLEASAGKRTFICIHYPPF
VSNRDERSSYDNIDEPGRTWLVELIEKHKPEAMFCGHVHNFWYDRLGQTETYILPSTAFV
RHDYAEFYRIGPGDQHGRNDGAKLGYFIVRLYEHGHVAENFRSYGRLLAQGETLPPPAQA
VRRLHSKEAGIDWLGLDMRQPWAEELEITPSGAVDEFERKLARNDYPVLALWEMGLRRLR
IPVQDLVNPRIRRRITVLQAAGHLFQVHCYGVPQGEDALALRAHAGLVDVLEVVIGWDDA
ADALRGIAQLKRETGLQIYLSRVNRRHAGKHEGGRYNHLISHGFTLNEADELADFFAASP
DCDAVDGLMFAVARDVAPALAVRAAAEIARRIAKTACLYIKSTSASPAESFEDDRANAAR
VAEAIVAAAGKPDVKIILDTFADSDRGYFVRTGLVDRRYNPKLGSHVVGNLIALLDGARW
VLAEESVALTGISGDRLILLLPGDGVPAWPVGAHWVDLATGAIHRKADGLAAAPRPLIVK
LPAPA
>A0A7T8RDD6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella bongori|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLTDAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELHANGLLETEVHRLQDTRFRPDTASEGY
>A0A8C9TQ48|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Scleropages formosus|TrEMBL
THKHQHSHVTLVLPSCDLTEETYQQLARETLEELDWCLDQLETIQTHRSVSDMASTKFKR
MLNRELSHLSEMSRSGVQVSEYISSTFLDKQNEVELLPPNQKEQNSAPCQTSGVGVLSED
SRATLPRFGVHTEHEDVLAQELENLDKWNFSIFTVAQLSCNRPLSCIMFAIFQERDLMKT
FRMPEDTLMAYVMTLEDHYHASVSYHNSLHAADVTQSTHVLLSTPALKAVFTDLEILAAL
FAAAIHDADHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLYEENCDIFQNLSK
RQRQSLRRMVIDMVLATDMSKHMSLLANLKTMVETKKVTSSGVLLLDHYTDRIEVLRIMV
HCADLSNPTKPLAVYRQWTERIMEEFFRQGDKERERGMEISAMCDRHTASVEKSQVGFID
YIVHPLWETWGDLVHPDAQEMLDTLEDNRDWYHSIMPQSPSPPAEQDDVDHFQFHPNIEG
DGQDLIQESTVTLWAQRQVTETSLYTFSLSHSPAPWAE
>A0A3D1Z8T0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp|TrEMBL
MIEPEREDITLVQITDTHLFADDKGELLGVNTLSSFSAVVADIKKQALAYDALIMTGDVS
QDHTDESYANFEQGIAPLNKPCYWLPGNHDYQPSMQSVYPSTQIQQDTHLLVGQYWQVIL
LDSQAEGSPHGFLTEQQLQYLSGCLSAYPDRFSLVLLHHHPLLVGSQWLDQHCLHNSDAF
WKALEPFNNVKAVLCGHVHQDFHQVHQGVEVLTSPSTCIQFKPQSNDFALDKVAPGWRSL
ILKANGQLETQVYRLEGEEFLPNFEAQGY
>A0A2D4GV50|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micrurus corallinus|TrEMBL
MLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKLPMSQISGVKKL
MHSSSLTNSSIPKFGVKTDQEDILAKELEDVNKWGLQVFKIAELSGNRPLTVIMYTIFQE
RDLLKTFKILPDMLITYLMTLEDHYHADVAYHN
>A0A3M2H4F0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. AOB-7|TrEMBL
MPSLPTPSADSSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIERVQQEQAQIDLILAT
GDLSQDGSQASYQRFRQLTAAIGAPARWLAGNHDEVPPMQAACNGSALLEPVIDLGAWRI
VMLDSSIPGAVPGFLADSQLELLERALSEAPQRHHLICLHHHPVSIGCKWMEPIGLRNPD
ALFAVLARHRQAKALLWGHIHQEFDQQRGGLRLLASPSTCVQFAPGSEEFQVGSEAPGYR
WLRLHADGRLDTGVSRVTGIHFEVDYSVKGY
>A0A8B9QNQ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Apteryx owenii|TrEMBL
IFLKVVCDVTASRPGRSTGKISYECFFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQ
RRESFLYRSDSDYDLSPKSMSRNSSIASDIMQPFCLFQVLASLRTVRNNFAALTNLQDRA
PSKRSPMCNQPSINKATITGKRS
>A0A8B4YVB4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Raoultella sp. BIGb0149|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRQCDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISSAKRVLLGE
RWQVLLLDSQVFGVPHGELSDFQLEWLEHKLAAEPERYTLLLLHHHPLASGCSWLDQHSL
RNAAALDRALAAFPRVRHLLCGHIHQELDLNWGGRRMMATPSTCVQFKPHCDNFTLDTVS
PGWRWLDLHPDGTLTTEVCRLSGVKFHPDIASEGY
>A0A089RHN2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cedecea neteri|TrEMBL
MESLLTLPVADGGRIRILQITDTHLFAGKNETLLGINTWKSYQAVLAAIHAEQRTCDLLV
ATGDLAQDHSVEAYQHFAEGISSIAAPCVWLPGNHDFQPAMFGALQEAGISPAKRVYIGN
HWQILLLDSQVFGVPHGELSDYQLEWLERQLAAAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAAALDAVLRPWPQVKTLLCGHIHQELDLDWNGRRMLATPSTCVQFKPHCANFTLDTIE
PGWRWLDLYPDGSLTTEVCRLQTGKFSPDTASEGY
>A0A4P6ZFQ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chryseobacterium salivictor|TrEMBL
MQRNILIITGILFALEFYVYQAFKTVTNNNSLRIAYWVITVLVYLFFIYEVLNFKRTERD
HQQVQIVASVFLVFLLPKLFVVFFLLIEDFGRGIKYTVQLFGTAENHIPERRKFLSIVGI
GTAALLSGLFLDGIVFGKYRHSIRKVKLKIAGLPKSFSGYKIVQISDVHAGSFLRPEKLQ
KAIDLINEQKPDLVLFTGDMVNNYASEFKPFVDLFQSIQSKDGKFSILGNHDYGDYGTWN
SAAEKAQNIPNLIELQKQAGFEMLRNEHRIIEKNGEKLYVLGVENWGEKPFPQYGDLDKA
SYGIPAEAAKLLMSHDPTHFDAIVKNHPSNVQLTLSGHTHGMQFGLDLKNVRWSPVQYRY
KKWADLYESNGKSLYVNRGFGVIGYPGRVGIDPEITLLELS
>A0A431WHX5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella atlantica|TrEMBL
MLKEAISYSIDDNASVRVVQVTDPHLFADPDAQLLGVNTAHSLEAVLNTINAVHYPAHFM
LATGDISQDYSSESYHNFVRAIAPLELPCHYLPGNHDDPRIMHLNMQGPNIYGQRRILAG
NWQIIMLDSTVRGKPGGHMADSEIEIIKSAVADQPDRHTLLVMHHNPILVNCAWLDQHCM
DNGSDFIEQVAEIPQVKGLLWGHVHQKLDQEHRGKHGIMHLMATPSTCIQFKPQSSYFAL
DALQPGYRLLELKANGTILTNVYRVPGDNFSPDREASGY
>A0A834XVW2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aphidius gifuensis|TrEMBL
MGCWPSAMLRCIRKKNFDCEKPSYLMPQGDNADLSHTPDVDFWKDKTMVGSSMFGDEDME
CTIAKGPQDFNSTLSITTASQVVKVLLVFPRDDHQLEALGTVSTKLGWSVSIAKNAETAA
EIFQNRSHDLVIIDRRGHRATDGDTTCRAIKATNCHHSSVILALVKKSFFTVVDKDEIVT
LDLLNTGYSRAMTECTHESILSNQLIGIYASEIQPRMQFASAHALYVAVDRCRDMVHVTD
DQHIVRFVNKASERLLGYKYEEMLGRNLSEIITCENFTLMDQQLQRGREFEGNMNCRRKF
NDTITINCRIIPFCATGKKPSHYVYVHDTMYLLENMGVAAVTLGGQHPRGSLHSLRRGSF
DVKSIGSDIGTQRRSSLQKLNNMPLEAPITKVLTLLTNAMNEIAPTNSELAMQIDKAIET
LKTTELYRPYLKEDTKIYNDPISSDLLGALLSNNSHYIRDSRRSSNDSTRSTHARICLPM
SMRIQLKNPQIPKEIEELLDHNLDWDFDIFSLEVLTDRKPLVYLGMNLMCRFNVPARLNC
DEKTLLNWLTVIEYNYHLENSYHNSTHAADVLQATARFMQSDRLQMILEPMDEVAVLIAA
GAHDIDHPGRSSQFLSNSDNKLAVLYNDLSVLESHHAALTFKLTLADENVNIFKNLDRET
YKLVRQNVVDMILATEMTKHFEHLAKFVNVCSSRCGDEFYPEGPDMATLLLPENVKLVKI
MMIKCADVSNPTRPLRCCIEWAKRIAEEYFNQTDEEKKSRMPVVMPMFDRNTCSIPKSQI
GFVDFIINDMIEAWDAFIDMPEMISYMRQNYDKWKEYHEKGISTLSDIERLQTSSELKIP
NLINSR
>A0A6N7LNT9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alcanivorax sediminis|TrEMBL
MTQQLQPLRIVQLSDCHLFADVSGKLLGLNTQFSLDKVLELIRKEQPNPDLILATGDLSQ
DASFESYQRLDDALSTFQVPVYWLEGNHDKPAPMLEALHAQRDRMSPCVLEQDAWTIVML
DSTIPGEVPGELFDEDLKFLDNALRNAKGEHVMVCLHHHPVPMDCAWLDTQLVGSADKFF
DVIDRHTRVRAIIWGHVHQEYDSERNGVRLLAVPSTCVQFKPGSEDFAVDDTNPGYRWLD
LYPDGSIDTGVSRVEGITFEVDFSVKGY
>I0QNQ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia sp. M24T3|TrEMBL
MESLFELPLVDGAKVRILQITDTHLFAGEDQTLLGVNTFRSYRAVLDAICAQQREVDLIA
ATGDLAQDQSLEAYHHFARGVSRLNAPCVWLPGNHDFQPAMVDALAEAEIRPSKQVLLGK
NWQVLLLDTQVFGVPHGELSEYQLEWMTRCLDQFPERFTLIMLHHHPLPSGCTWLDQHSL
RNAHTLASVLEDYPKVSTLICGHIHQELDLDWYGKRLYATPSTCVQFKPHCTNFTLDSVA
PGWRYLTLHPDGNVETEVCRLQSDEFSPDADAEGY
>A0A3S0NDQ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio penaeicida|TrEMBL
MKLSLDSNRDIRLLQITDTHLFEPEDGCLLSVNTQDSFHAVVNTVISRKLEFEAILATGD
ISQDHTAASYQKFEEGIAPLKKPCFWLPGNHDFKPGMHSIFPSTQIKTTSHVVLNNKWQI
ILLDSQVEGVPHGRLSQEQLDLLESKLTEFPEHRTIVLLHHHPVLVGSHWLDQHTLKDAD
DFWSVLSHHQNVEAVLCGHVHQDFDVMYQGVRVVATPSTCVQFKPNSDDFALDNESPGWR
MLTLTREGELKLEVGRLSDGEFLPDFSAGGY
>A0A5I6QRG2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Kiambu|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A1C3J4A0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio atlanticus|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDAIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLDKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGNN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWEVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDNLSP
GWREIELHQDGSVSTQVRRLPHGQFLPDFEAAGY
>A0A7D6WMJ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter freundii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRAKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>H2Y9V9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ciona savignyi|TrEMBL
MILHSASLAPAKRRESFLYRSDNEFDQSSPKIGSRNSSVVSDAHGVEDLIVTPFAQVLAS
LRRVRNDFIVLTNIHPPNKSPTGHGKMSTNSSPTIPINAQGNVVPGTEEFIQRATNTIEE
LDWCLEQLDAVQTHRSVSEMASNKFKRMLNKELNQLSGMSKSGNQVSEFISSTYMDNQNE
VMSPSHDPSEDKEKRPASPNCGLMSKSFNKSHLNPTGKIMGNVTGIKHCNR
>A0A2P7ZLI1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces sp. 111WW2|TrEMBL
MRIVHISDLHARADWEPDQSKVLKAFLTDVRGFHKQAPVDAVVFSGDLAFSAQPDQFAFA
REALLDPLQDMLGLDRGRMLLAPGNHDVDISRIDQFQEDGLRSGLSNRDAVNRLLDAPNL
TAYLGRMAPWLEFRNDYYAGTDVDLSSPLVTLHRFKLRDSEVAVATLTSAWRATGAGDDA
DRAHLIVGDRQVVHAADRLGDADLKICVMHHPLDWLAEFDRHDVRRETSRFDMLCTGHAH
VVDPLGLVSRTGTLMHSAAGSLYQTRDYFNAYSVVDVDRPRAPHAYTVHVRSYFDARDAF
DQGVDMMPEGKQVIDFDAPGGRPVRSTASEEVAVTRTAADLAAEFLLDAVRERSLLMAGP
DRWQLDMDGLLVPPVLLHLPVDQYLALTDLEDGRITPDDLRASLSEYRHFVIVGDEYSGL
TSTLQWLTHTAYGLDSQYAPVVIDFTAVGSGGNGVEREVRTQLARAGIPTGKRDVLPRLA
LAVDNVDPRSEKRLRNLLKFMAQYPQNMYLLGSRTAVSHRLNDELGREGWVSRVRYLGPF
GRRELRALVRLLRPEEADSDVTAMLDLLSRGRLPHTPAMLAALVATAGHGDWTSGVNSTA
ILESYLGLLLGRDDPSVDRRYELDFRELQDILSCLNEHLTLGGRDALPRMEAEQFLLDYF
KGLGWSEPSGAVLDALIAKRILGQRDGQIYFCQPMVRPLLAAYRMEDSEGLKAMVLANPL
DYAQVIRHAAALRRNDTSLLACVMDGFRQVREGLGDGANDPFSVLASKDGWRGRDDTESL
LDDFWPTDLAYEPPAPPAEVQGELNVLMDGLYDQADAMRTIAQDKRRDGVLVRSDFEVFV
EWLDLLADVLRSSELVRDLDLKRRALRLTLNGYGVRAALMADEWKTRDVGRSMRAALSEA
LERPELRESLVNGTEVSDAEFEEFLGRIELFSPVLASYGSLSQVLTSSKLSRLTDEALRE
AEFIEQPGQALMAVLLMRRMGDREWVRHAADVTRLHGEREVISEIMRLFALTSYVGTDLG
RDELGSYESLLVDIAVQHKELPTQGPTRARDYQRNQFVQALRNRRLRFMQRGGDDDTKRI
ERF
>A0A3Q4MGF4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Neolamprologus brichardi|TrEMBL
NFQGGKSPSLTLHTTFPQGQRRESFLYRSDSDYDMSPKTVSRNSSLASEGHTAEDFIVTP
FAQVLASLRSVRSNFTILANVSTPTVKSVSPPVVHRVYVS
>A0A6G8NJB4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Caballeronia sp. SBC1|TrEMBL
MKIRVLSDLHLEHDEPLAIPYAEADLVVLAGDIHNHAEGLRWAAENFGSEVPVVYVPGNH
EYYDGEFGALESAMQDAARSLPNVHFLNNTALTDRYGKWRVLGTTLWTDFALFGPSDEAL
RESIAAAERVMLDFRGVIQVAWPEPEDEPRSFSPSDSLALHEQARAWLEHELAKPFDGKT
IVVTHHAPLKQSLAEKFATDRASAGFVSDLASLVRAPVALWVHGHTHTAFDYVAEGTRVV
CNPRGYRDRRTGAPENPLFKWDKVVEI
>A0A704QW14|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEVGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A737QUQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPPCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A6L5BW75|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas frederiksbergensis|TrEMBL
MNSPFLIAQISDLHLKADQKLTYGVVDCLGALRRAVDHLNASHPRPDIVVISGDLVDFGR
PDEYAVLKRELARLHMPVYLVPGNHDDREQLLAGFTHHRYLPTDANAPLDWVVEDHPVRL
IGLDSTRPGAHGGQVLDSQLRWLDEQLSRRPNVPTLLILHHPPFITGIGHMDRESFINAA
ALEALVARHPQIERLLCGHLHRPMQRRFGGSLSCVCPGTSHQIVLDLEASAPAHFNLEPA
GYLVHRWHPQHGLVTHNAVFGEYAGPYPFYDVHGLID
>A0A0X8LKA4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio fluvialis|TrEMBL
MNVSSSIDNSDSIKLVQITDTHLFAPDDGSLLSVNTADSFLAVVEAIRAQQLEFDAILAT
GDISQDHTAESYHRFTQGILPLEKICFWLPGNHDYKPNMSSVLPSKQIHAPEHVLLGEHW
QMILLDSQVVGVPHGRLSDQQLTLLEEKLSAHPERFTLVLLHHHPLLVGSAWLDQHTLKD
SEAFWTIVERHQNVKAVLCGHVHQDMDRLHHGVRVMATPSTCVQFKPNSDDFALDKCSPG
WRELELHADGRVTTAVKRLAKGLFQPDFNSNGY
>A0A379PX86|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYGALQEAGISPAKHVLIGE
EWQILLLDSQVFGVPHGELSEFQLEWLERKLANAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSLLAHFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>W8UUB9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pneumoniae 30684/NJST258_2|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A7R9G958|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Notodromas monacha|TrEMBL
MYIGQCTMRAGYRSPDPKSQRVHQCNDEEPREGNRASNRTVIGEPFSRGVLVNELLQLEV
LVRMRQQIQFGEAAFQALECCRDLVQITDPSFKIQYANKACEKVLGYAREDVVDASIHDV
TKDDVVSSSSSSERIGSSAPLPEEGVSPPPASGGGLSVSLSCLKQGKDWEGSLTCRRKSG
DYIPLQTRVSPIAPQNGHADHYVFVEECPVLFLDKGLLNEIYDSAYPRPPMSRGSLFSAR
KFSTDVRSLTSEVGRRQSIAKQHTTTVEAPIFRAVNLIHAAKENSPGHVTQALDKVLEIL
RSAELYSPVFSGQQSRNEDPLANDLLGGLLALHLALSNANSVGPATPMSPPHGIKNPFPY
SSPLSQASVEVRGLLEKEKTWAFDVIKLEEATKKRPLFYAGMATFMRFQVHAVLNVDLKT
LHNWLQMIEAHYHASNPYHNATHAADVMQAIGYFLEFPVIKEAMEPLDNAACLIAAVIHD
LDHPGKNSAFLVNTRHDLAVLYNDTSVLESHHVAHAFKLTLSDPRFNIFKGLDRETFQTI
RRSIIDMVLATEMTKHFEHLSKFKNAFDSTSGVSGDDADSVSNEPQGSDSDAQGENEQAV
AWATTENIVLVKRMMIKCADVSNPVRPLHLCQEWGYRIAEEYFQQTEEETDRGLPIVMPL
FDRRTCSIPKAQIGFIDFFITDMFMAFDAFADTPELLERLKHNYEFWKLENQRLMEAEAE
QSSPL
>A0A8C2NQC6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Capra hircus|TrEMBL
MLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVK
KLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIF
QERDLLKTFKISSDTFVTYMMTLEDHYHADVAYHNSLHAADVAQSTHVLLSTPALDAVFT
DLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHC
DIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDR
IQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQIIHTATITRGGESLSRISLLPHGQ
SPVLCPKYAYFIYMCVCIYIHTHTHTHTHIDMGFPGGTSGKESTCQGRRLKRRGFDP
>A0A4Q4GWM2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter piscicola|TrEMBL
MSTYQINSKNREPVIIQISDTHLMTDPNEHFIGISPEQNFHAVIAQILQEHPHIDAIVHT
GDLAQQATTETYQRYQAYMQSLGIPFFQIPGNHDDLNLFPFLMPLPEPACVEIGDWCFIL
LNSAVPKQVDGWIQTEQLLHLTHLLQQTQDKFVILACHHHPFEMHSQWIDQHKLKNTDQL
TTLLSQFTHIKAVLFGHVHQESIHVWNNIQFLSTPATCAQFKPLSENFALDEAAPGYRYL
HLKSDGQFESAIFRLKDYNQTINNEISGY
>A0A7Z3BID5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas multiresinivorans|TrEMBL
MPTQSTASDSVLVVQLSDSHLFAEVNGRLLGMDTADSLTQVVRLVGEEQPAIDLVLATGD
LSQDGSIESYQRFREITASIAAPARWFPGNHDEMGPMREAVAGTDLLDPVIDLGAWRVVL
LDSTIPGAVPGQMTVEQIHLLERAIQAAPDKHLLISFHHHPVPIGSQWMDRIGIYNPERL
FAVLDRHPNVRCLLWGHVHQEIDRMRGDVRLLASPSTCVQFTPGSEDFCVDSPAPGYRWL
RLMADGRVETGVSRVTDIEFEVDYSIKGY
>A0A1Y2SHW8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus vietnamensis|TrEMBL
MESLLEIPVAEGATARILQITDTHLFANKGDSLLGINTYRSYHAVLDMILEQNLDIDLIV
ATGDLVQDQTINAYQHFAEGIARLPVPCVWLPGNHDYQPAMVDTLAAAGISPSKQIFIGQ
HWQLVMLDSQVQGVPHGELTDYQLEWMKKCLDENRDRHTIIMLHHHPVPSGCTWLDQHSL
RNAPELSEYLKGRTQVKAILCGHIHQEVDEMWNGIRVMATPSTSVQFKPHCTNFMLDTVA
PGWRYLELSVAGNSVTGNKEAKLQTQVHRLKSNEFCPDLDSDGY
>A0A379XLB0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. indica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLVNFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A220UQK2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella bicestrii|TrEMBL
MLKEAVSYSIAEEESVRIVQVTDPHLFADPEAQLLGVNTSKSFAAVLNTIRAVDYPAHLM
LATGDLSQDYSPESYRQFVAAVAPLNLPCHYLPGNHDDPRIMFLHMQGERIFGQQRILVG
KWQILMLDSTVRGKPGGNMAESQFELIEQAIAAHPDRHTLLVMHHNPILVNCAWLDQHCM
DNGTEFLRRVAQYPQVKGLLWGHVHQQLDTDYDGPHGALQLMATPSTCIQFKPQSPYFAL
DGLQPGYRLLELKADGSICTNVYRVPGNLFSPDKDSSGY
>A0A2S9PLV7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia pestis|TrEMBL
MESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTFHSYRAVLDAIIAEQHPFDLVV
ATGDLAQDHSVAAYQNFAKGISRLPVPCVWLPGNHDFQPAMFDALAEAGIAPSKQVLAGE
HWQILLLDSQVFGVPYGELSDYQLEWMERCLIAYPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAILTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDAVA
PGWRYLDLLPDGGLETEVHRLDSDEFCPDMDSDGY
>A0A6A4K4M8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Apolygus lucorum|TrEMBL
MNSYNLDSNQLKFELRRRKLTTDGDLPVLAARLNLGILMGNPVVDVDVDPTEELKYCQDE
IDIVIGEASQIKAKTRTAKVIKVQSKTLHIINRLENAKGMEGADVPGIEALLVVVRDLVV
QVESNIAARIEVSESEVSDIDGAISKKVKSPRPRIIVKKSGSEVDHGARRKYVPVHKWNL
KKFDGNHREDALDFLRLVEDTARARMVTDEDLLEESADLFEHRALKWHRDAMRRVSTWDE
LKREFKIAFQVHAADGALREQIRNTKQSVGEGIDMFLSTMADLYDRLERPLPEVERLEEI
LRNLSPFLKDQLYSVEIQTIEQLRKLGRRAEAGRVRMGEVDERNHSRGQRDAFRAAPRVA
PIEATRTHEVTRRPFDATPFTCFNCRKDGHRFRECGVVRAKSGVSEALTTICKVRNWSHG
VQPQPEGDLQINKCSKYDDLQTPDKKEKKEEKVKTPIMNMKMVVGTVASNPDQLLPEMYE
SLLKMESIQSSIALSKSVFAVLEKCRELIMITDNNNCIQYVNAPMARVLNHTPSELIGQI
ATVFQEHSDLQPAIRTLERGFEWVGRIRWRTKSGDSVSLQCRSTPISPAPSYPTYYLYLL
DSPSDCHFPRGSVPSLRKGSYDLKSIISEGSARRQSLAKLHNLPLEAPITKVLSLLCAAQ
ENAPPNVIGMLEEVMDILRTTELYTSHLKTDNLRAEDPLTTNLIAALVAKGPPSSIMPRR
SSGDSPTKKKLMYKKNANVVLPASKELKDALKKINTWEFDVILVEKLTSGKPLVYVGIRI
FSIFNACKILGVDEKTVYSWLVLMENHYIPDNSYHNSTHAADVLQAAACFLLKLRSKKLL
EPLDEICCLIAAVAHDLGHPGKSSAFLTNAGDDLALLYNDISVLEQHHASLTFRLTLADD
RVNILRGLEQSKYSTARSCIIDTILATDMYKHFEHFTKFVTIYSKSSEDVPEKNEKDKPG
DSEVDVNPEDVVVVKRMLIKCSDVANPTRPLLLCKHWAKRIAEEYFTQTDEEKERKLPVV
MPLFDRSTCSIPVSQMGFMDYIVNNMFEEWDAFLEMPETLYNLRKNYDYWKDLNDKGCVG
IEEDTNGKKEEPDSAQI
>Q8CZS2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia pestis|TrEMBL
MGGRQKQGYHLESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTFHSYRAVLDAII
AEQHPFDLVVATGDLAQDHSVAAYQNFAKGISRLPVPCVWLPGNHDFQPAMFDALAEAGI
APSKQVLAGEHWQILLLDSQVFGVPYGELSDYQLEWMERCLIAYPERYTLILLHHHPMPS
GCTWLDQHSLRNAHMLAAILTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPH
CTNFTLDAVAPGWRYLDLLPDGGLETEVHRLDSDEFCPDMDSDGY
>F4TIV0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli M718|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A226E0K5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Folsomia candida|TrEMBL
MGCSPSTPSSETAPDDGDDTHDDHRAQDGGGKSSLKLKFSSPEEDNIQPCYSGSGLPITF
RTPSNTNIVLNASSSSTPFVRMIDQQRYFDKPEPGCRGVGNLVRLGPMSIFRSTPIRLSL
IFPKEDSLHNGILAGCDRLAWEPGVRLTSIPDQLSYLGHDPFGINLLLLDYRQPKLLPLN
ILPVIRSLKDENSTLVVVAFVKKNSLDKCESVICNLQDYGVDWVETDCGLTSSNHWHHQL
AQYERCFLLPALKLGSAKTLLVALDQCRDMIQITDSSHRIQFVNRAYERLMGYSCEEITG
CDFHELQTRGGGGHHNSLTMEPDVQGRNDANSPTTLNTGGRVSPAGAAVATTSQQGQHHG
HPLPPPFHDHLLQEISHGKEWEGNYMYNPKAGDPIFLNSKVLPFNVNLNLNPSVNPTGNA
NYASSSPTSDILAGMTKCKLGSTHYIYVSDVPSVYAEKGASSEVGSNQDVGYPMPRGSLK
SLRKASYDIKSISNDSSILRRQSLAKLHSLTIEAPITKVINIIAAAQQNCPLYIAQALEK
VLEILRTTELYSPQFFEGGSKIKSDDPLTTDLLGALLSQGPRLSTTGRRSSNENTASRLA
PRPSLPDIAEAPTSLQKLLETEERWSFDVILLEEITEKRPLVWLGMTIFARFGVAQVLQT
DEATLRNWLTLIEANYHTTNSYHNSTHAADVMQATAYFLSTERLKGFLEPLDEVIALIAA
VVHDVDHPGKTSPYLINSQQDLALLYNDLSVLESHHAAFTFKLTLSDARVNIFANLEPDL
FKIVRQSLIDMVLATEMNKHFEHLSKFVNVFTKPFLREDNQCGGQSDHTPLTPTEPDIST
LITPENVVLIKRMLIKCADVGNPTRPLKQCVEWSKRIAEEYFRQTEEELARGLPPVMPMF
DRASCSIPKSQTGFVDYFVADMYEAWDAFIDVPEVIEHMKYNYDYWKEQDKLGLRDATLN
ETYLQKYPQPVSRFVSLRSLEQSQL
>A0A366A5E8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. 2017V-1124|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFATEEGSLLSVNTADSFAAVVAAIGEEQVEFDAILATG
DISQDHTPESYQRFVRGIQPLQKACYWLPGNHDYKPSMHSVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEHPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRLHLGARVMASPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>Q4QNE3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae (strain 86-028NP)|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELYSDGSIRTEVKRIQQAEFLPNMQEEGY
>A0A7U9AU28|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli TA206|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A0S7GWQ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
MIVTPFAQVLASLRTVRSNFALITGQQDRAASKTRSSGSNPPSMCKTSLAEEPHQQLAIE
TLDELDWCLDQLDTLKTRNSVSEMASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLE
KPDDMDIMSPTTKEKDKKKHPMSQISGVKKATHSLVPSTIPRFGVNVSQEEFLAKELEDI
DRWGLDIFKVAEYSGKRPLTVTMYTIFQERDLLKTFKIPADHFINFTMTLEDHYRSDVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAALFASSIHDVDHPGVSNQFLINTNSEL
ALMYNDLSVLENHHLAVGFKLLQEDNCDILQNLSKKQRQSLRKMVIDMVTPTSQPAQFRE
FRLSGVF
>A0A6G9Q870|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lentilactobacillus hilgardii|TrEMBL
MKLQIHDHHPFKVCQLTDIHLGDYPFNDADLKTLASLKVLFDTHSFNLIMITGDLLWGLQ
SSDPAKRLGKLYDLLNQYPTPVAITYGNHDTEGIFSRTDLREIESHLIHPADKHHSMIID
DRESYALEIYDGDQLAHIAYVWDSGAYSHSQKADQYAAVEPEQIDWFLKLPYARTSKEMD
LGFFHIPFPEYQSAANQLIDGVNHEKVCSPATNSGLFYALLRQKNVKATFVGHDHDNNFT
SSFRGIQLNYGNVTGYNCYGELPRGVREIDVSKDAIKTRIILFSETPDNCSD
>A0A2U3EWJ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. CGMCC 5087|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLTGAKFRPDTASEGY
>A0A7T8JAC8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica I|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYGALQEAGISPAKHVLIGE
EWQILLLDSQVFGVPHGELSEFQLEWLERKLANAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSLLAHFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A091V0Q6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nipponia nippon|TrEMBL
QFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISG
VKKLMHSSSLTNSSIPRFGVKTDQEDILAKCHMVWNSPLASLGQLSWLCPSQLLVPQAEH
GKLKSPCLVVKYCFTLMAKLEIFMKFYIIDNFTKGYGSLCVKSLKIPDAFQMCFALFTDL
EILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDI
FQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFHQGDRERERGMEISPMCDKHNASVEKS
QV
>A0A8I3QRB3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Canis lupus familiaris|TrEMBL
MQNAWHTLVLYECTSNVLLHDYVTRIFCFLLSFDVENGPSPGRSPLDPQASSSSGLVLHA
TFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNN
FTVLTNLHGASNKRSPAATSQPPVSRVNLQGIAAELLLRNDFLMGEIQVTCSLDFYTKEK
APSEAESLLLIQLINFAGKWPLAS
>E0SI53|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dickeya dadantii (strain 3937)|TrEMBL
MESLLTLPVARGARIRILQITDTHLFAGERETLLGVDTYRSYQAVLDAIAAQQCDFDLIT
ATGDLAQDHTQEAYTRFADGIRRFNAPCVWLPGNHDFQPAMVDVLARSGIAPSKHVLLGE
HWQVILLDSQVFGVPHGELSEYQLEWLERSLQSQPERYTLLMLHHHPLPSGCTWLDQHSL
RNAHSLDALLARFPRVRTVLCGHIHQEMDLDWNGRRLLATPSTCVQFKPHCTSFTIDNVA
PGWRYLELLPDGVLETQVCRLEGNEFLPDMDSDGY
>A0A1U9SV08|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPKRHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7U9FZA6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli TA143|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A3B3T653|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paramormyrops kingsleyae|TrEMBL
ALPCQNGQNGLSSVRSPLDSQASPGLVLHPTFPQSQRRESFLYRSDSDYDTSPKSMSRNS
SVTSEGHTEDLIVTPFAQVLASLRTVRSNFTILANVTTPTANKRTPMGSTPTVPKATLSG
RFNPPYQTLS
>A0A539CS49|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Beijerinckiaceae bacterium|TrEMBL
MRCLFVADLHYSLPQFDWLLRSAAGYDLVVLAGDALDVGSIVDYRAQTLVVRKYLQRVAG
ATRLIVCSGNHDLDSCGAAGEKVARWLADTGALNITRDGNSIVVDDTLFTVCPWWDGPVV
RAALVAQLEADARRRQGRRWIWIHHAPPRNSPTSWSGSKSMGGADLEQWIGQHNPDIVVA
GHIHQSPFVKDGSWADRIGATWVFNPGGQYGVTPAFIALETTVGEAVWISAMDVQTARLE
APLQRPIPSANAVPGWFAARASAPIPF
>A0A858Q7U0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylococcus geothermalis|TrEMBL
MPNSGTLRLLHLTDSHILADPEARFYGADSAATLRAVIEHANRDRFDLILFTGDLAQDPV
PQSYRRLAELCAGLRAPCYWLPGNHDQPALARRILDETPLLRATAIRLGGWLIVCLDSTL
PGCAGGSLAGEQLDLLERTLSDHPTLHTLIALHHHPVPCGSAWMDTMILDNAGEFFAVLA
RHPQVKAILHGHTHQVSDFEIEGKRVFGTPSTCIQFKPANRTFALDEEQPGYRWLELGQD
GSVATGICRVPVPTPPPPASASA
>A0A8C3SUG1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chelydra serpentina|TrEMBL
MKEQHSCVGTGHLSMAGYGSMDPLELAVSPVKRLRTEYSFPYLFAEEAYQKLASETLEEL
DWCLDQLETLQTRHSVSEMASNKVGPIGLPCPLFLLLTCYQSWKSSG
>A0A369Z9K4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus parahaemolyticus|TrEMBL
MNTFYPLEPKTSVIKLLQITDPHLFSDTTKDLLGVNTHASFQAVLDEIQAEIQTQAVDFD
AILATGDLIQDHQSEGYLHFAEMIRPLAKPVFWLEGNHDQQPQMSLQLGKFDYIRPEKQI
FAGDHWQILMLNSQVATAPSGYLSKGQLAWLNQKLSENPERFTLVVLHHNILFTHSAWLD
QHSLKNSDTLAEILALYPNVKAILHGHIHQEVDAIWNGIRILSTPSTCIQFKPNCDDFTL
DNLPQGWRELSLFEDGRIETEVKRLKTQAFLPNFDSRGY
>A0A0J1LSE5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. MGH106|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADVPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRAKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVCRLQGNRFHPDTASEGY
>A0A336NHQ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aggregatibacter aphrophilus|TrEMBL
MLNTYQYNTQQEVFRIVQITDPHLFKDTNGELLGINTQASFSQVLTEIQQQQYAYDLVLA
TGDLVQDSSDEGYLHFCEGVKALEKMVFWIPGNHDFQPKMFDLLTKDNISAKKHILLGDR
WQILLLDSQISGVPHGQLGEYQLDWLLAKLKEYPQRYSLVVLHHHILSTHSAWLDQHNLR
NAHELAYILAPFSNVKGILHGHIHQQVDGEWHGYKVMATPSTGIQFKPDSNTFALDTVQP
GWREIELYADGRIETRVKRIQHKTFLPNLQEEGY
>A0A1B8PEU2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus haemolyticus|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENHEFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQSPMDGAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAEFLPNMQEEGY
>A0A7L6PKM2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. RHBSTW-00127|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRAKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A6C6ZVD3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella dublin (strain CT_02021853)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A5P3AY98|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Phocaeicola vulgatus|TrEMBL
MKKIKTLCGVLALLCVGMMPVSAQNVLKFNADKKFKIVQFTDVHWVPGDSASEEAAERMN
EVLDVEKPDLVIYTGDLVFGKPASEALSKALEPVVSRRLPFAVTWGNHDDEQDMTRIELL
EYIKDMPGNLTSTTAGISGVTNYVLPLKSEDGKKDAAVLYVFDSNAYSSLKQVKGYDWIK
PDQINWYVESSVGYTERNGGKPLPSLAFFHIPFPEYNEAAQDENALLIGTRKEKACAPLI
NTGLYAAMLNAGDIMATFVGHDHVNDYVVDRKGILLCYGRFTGGNTVYHDIPGGNGARVI
ELTQGVRSFKTWERLEGGKIINEVNYPSDFQRE
>A0A7K0CG14|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces smaragdinus|TrEMBL
MLGTNRRGRFHGSRTALMATAAALAFATTPALADGVPQDPVTPTAIADNDGMDLGSTSRP
IAPGVELTSFDRLESDKWLRADALSVDLGGSARVDYLADDVSGRKTVADLVKTHDAGEGR
RTVAAINADFFDINETGAPLGPGIAGGQVTHSPSAGAEEAVGIDADSAGRLLKLYFEGTV
TLPDGPHELASFNAANVPGGGIGMYTAHWGTADRALTVDGAARTTEVTVRGGVVTAVATA
PGTGAIPEDTTVLLGRDAGADVLARLTPGDAVRTEYRPVTDGGDVPRTVVGGRGVLVLDG
VAQNWEGRPNNPAAARTAVGFSQDGRTMHVLTVDGRSGDTGGVTLTELALMMKQLGAYSA
LNLDGGGSSTLVAREPGSDTPQLENTPSDGFERVVPNGLAITAPDGTGDLTGFWVETAAD
PAKAPSADQVPGGHPERVFPGLHRALTAAGYDETYGPADGTPAYWTSSEPRSGTVGADGV
FTAREHGGPTQLTAHRGTAKGATTLTVLDRLARIRPTNDRVGLKDAADRTGFGFTGFDAS
GHSAPIDPADVDLSYDASLITVTPDPAAGGFTVRAATPDALATRVTATVQGHSTVLAVTA
GLYEQDVATFDDAAQWTYTTARATGAIAPTADAHEGTGLRMTYDFTQSTATRAIYALPPA
QIAVPGQPKSFGLWVKSDGKGAWPSLQLTDGAGVTQILRAPYLTEPGWQQLTFEVPQGIT
YPLKVVRFYIAETVPAHQYASEIVIDGLTAQTPPAVDLPPAPAVADPLIGTGTDVQGRDW
RFAVMSDAQFVARDPDSDIVRAARRTLREIKAQHPDFVVVNGDLVDEGSPADLDLAHRVL
DEELGGELPWYYVPGNHEVMGGTIENFVSEFGPAQRTFDHKGTRFITLDTSRLTVRGGGW
AQLKELRAQLDAAAADPAVRSVTVIEHVPPRDPTPQKGSQLNDRKEAALMEDWLGDFRRT
TGKGVLFVGSHVGTFHAEHVDGVPYFINGNSGKNPATPPAEGGFSGWSLIGVDAVSPGEQ
NAARLKPWTGGPDWVTVQTRPHVDGLTLNAPAELGAGEEAAVTASVTQSIGATTRQVPVA
WPVSGDWTGTPNLWIGAPSHAPDGAVAAYDPATGVLTGLRPGTGTLTVTVNGVPQASPVT
VS
>A0A345C664|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Leclercia sp. W17|TrEMBL
MESLLNLTVAGGAPVRVLQITDTHLFANKHETLLGVNTWESYQAVLEAIHGQKRECDLIV
ATGDLAQDQTAAAYQHFAEGTASFHAPCVWLPGNHDFQPAMYSALQDSGISPAKRVYAGD
HWQILLLDSQVFGVPHGELSDFQLEWLEAKLAAEPERNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDQVLEKFPRVKHLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLEGTQFRPDTASEGY
>A0A0J9U9F1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila simulans|TrEMBL
MGCSPSTLPPAPSAGQTGERGSLPLDASEKDESRLFCIKLRRSRLRRCSCGGVTLQPPSD
GNGSTAGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHSVVRRATGSTG
TSGTSSSGGNSRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLVFH
KSDSICEAITAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSSKNLDAEH
IARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQIL
HSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLE
DIFVSDLSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVP
GGQMDFIATLPQPKDAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKII
NLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYS
SRRSSNDSIIRTGSSTRTAAIVPAKMKSNPIIMELLDESLSWDFDIFKLEEITDYHPLLY
LGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLT
NKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITF
KLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPRDHNP
QTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMF
DRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLTEI
MAKQPPVGKMANSKXHTAFRRLFSGLLKPLPAQAPGTSTIGENEMEDVL
>A0A1K2G1S8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces sp. F-1|TrEMBL
MVRVPFAARFRRRRRPLPDLELAARPRPWLGALGLTGVVLVGAWLGLLVVGNVRTPVGPM
NTTMALRPSLSGGTKINVSPLGALTLDSHVAPVRLDVNVDQLDPLRSQELVDHPERFSGL
QGEVVHDVEHGTLDLAVRSGAAVVAGAGLLGLAVYRRPRRALAAGGLALTLLAASGVSAY
ATWNPKSVMEPRFSGLLSSAPSVIGNARSIVTGFDVYQKELARLVTNVTKLYDVTSTLPA
YQPDPSTIRVLHVSDIHLNPASWKIIASLVKQYKVNVIVDSGDTMDHGTAAENGFLDPVA
DLGVPYVWVRGNHDSRTTQGYLERMKNVRVLDDGHAVTAGGLRFAGTGDPQFTPDRAVVP
GGDAAERLAGDRLASALRSQRAAGTPVDVAIAHEPAAARETDGEVPLVLCGHLHHEGYEK
LPYGTRLRMEGSTGGSGLRAVEGKYPAPIEASVLYFDRDTHRLQAWDAIQLGGLGLTTAE
VSRHLADDNHPGASPGASPGATPSGTTAPARP
>A0A5B8HVF0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dickeya poaceiphila|TrEMBL
MESLLTLPVARGARIRILQITDTHLFADEQGTLLGVNTYRSYQAVLNAIAAQQYDVDLIT
ATGDLAQDHTQDAYTHFANGIRRFNAPCVWLPGNHDFQPAMVDVLARSGIAPSKHVLLGE
GWQVILLDSQVFGVPHGELSEYQLEWLERSLQSQPERHTLLMLHHHPLPSGCTWLDQHSL
RNAHSLDALLARFTRVRTVLCGHIHQEMDLDWNGRRLLATPSTCVQFKPHCTTFTIDNSM
PGWRYLELLPDGGVETQVCRLEGNEFLPDMDADGY
>A0A8J4ZS47|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nymphon striatum|TrEMBL
MELFLNSSNITFFSNLREWETDFGFQLVWHFFATSHGKGTCCGWDRGNIETVCIRRVVRA
GANSLVDAASYAEIATQRNPNINVVFIHITEEVKSQVDNKLAQWDVALAIPNTPKCHCFS
ALIFIETCSVKTCLIELIQLEHNLMRFINKMAASDALLSAAESSKEAIQITNSNNQIQYV
NKAYEKLSGFKKVELIGSNIQQIFGLDSSKFESSSTESNGKNWEGFTEVKRKSGEVIAVD
YRLISSSESRNPSHIIYVNGSISRANKSCNTDAPFGVPMFVRRQSVAKLHAMTIEAPITK
VIKIITAVSENSPPEISDSLEAVLDILRSTELYNPQHLTNQSMNPFEDQTTSDLVGGLML
QDAKKPTHTIYRRQSQESSSMKVDTYAICYLRRLTFIKIGQNQSGGLQLIADFESAPSSL
KSVLEKESQWDFDVIELEKLTSKRPLVWLGMTIFEKFQVSYHNSTHAADVLQATAYFLRL
PRIKMMLDPMDEVACFIAAIVHDVDHPGKTSAFLSNSSSELAILYNDLSVLESHHSAHAF
RLTTTNDKVNIFQNLDRETYRSLRKSIVDMVLATEIAKHFEHLTNFVKKFLEPALDIPET
SPSEIFNVQEPEPLMESLITPENVVLVKRILIKCADVNNPLRPWNLCRKWAIRIAEEYFA
QTDEEKRLNLPVVMPAFDRTTCNIAASQIVFIDIFINDMFTSWNAFIEMPQLMENLKNNY
SYWKERDKTSSSPSPKQYSQPPELSDVEEINLEKD
>A0A2I8TJ27|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter freundii complex sp. CFNIH9|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRARYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A658GD33|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. SST3|TrEMBL
MAAAPPTAEKDSVLLVQLTDSHLFAETGGKLLGMDTAESLQRVVDLILDEQPRVDLMLAT
GDLSQDGSVASYERFRQLSERIEAPVRWCPGNHDELDAMRQAAGESQLMAPVLEIGTWRV
VMLDTLVPGSVFGMLRDDQLELLEKTLLQAPERPHLVCLHHHPVMIGSRWMDSIGLHNRE
ALFEVLDRFSCVKALVWGHIHQEFDDWRSGVRLLATPSTGVQFTPGSEDFQVDTRAPGYR
WLRLYADGALETGVSRVVGIDFEVDYSVKGY
>A0A7G9Z9U0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methanosarcinales archaeon ANME-1 ERB7|TrEMBL
MYPRLFLIIILMMAVSVITLADTVTATDTIADANGVGDASESFTFVHMTDAHIGYYDIKE
LTDDPRICKLIKAVDPKSMVESVVKFTDTLQDIKTHKPDFILDTGDLVESNNRDFFNAYA
EILKSIDIPVYNTPGNHDRRDRYGQGDNLTNYYDIVKPLNGSVDAVLLDDFGDYYFDWKG
YCFVGLDSGADYSVYTEWRDINPTMLPYLLLLCTPESNGLWCSQMEQLYTLDPNIPKIIF
MHHPVINDKDDENLYDYKVRVPNNCSDYGGNDACIAKNRCDFIAYCLNNHVYLLLTGHTH
KDYVAVHAPPVAVPAITEPYMFIQTRSATKDEQGYKHGYRVINITDDVISNITSETTPTL
NRSTFTLSLADPVAEPEHIWGISVRDSLGRHTGMNWTTGDIEREIPGSYYTGHYNKPPSD
TPQVLVVYPADNSLEVVYHALEYGDGTTLVTKEPDVSIQRVVDF
>A0A5J4E932|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium MnTg04|TrEMBL
MNTATDNPGHGDTLRLLQVTDPHLSANIGRAMRGVDTYRSLQDVLDQTADLGWLPDAILA
TGDLVHDGTRQGYEHFRKLLGRFAARNNARVFTLPGNHDDPETMRETLSNDPFQYCGHAD
LAAWRMIFLDTWLAVDAGGLLRDSELERLDDLLNEAGDKHVLVCLHHHPVDMGSRWLDSV
GLRNADRFLEIIDRHANVRSVVWGHVHQEYDNIRNGVRYMSSPSTCAQFKPHNDDFALDE
LPPGFRWLELAADGSISTGVEWMKVPAAKATVR
>A0A6D1S0I1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Raoultella terrigena|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLEAIHASQRQCDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGE
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAAEPERYTLLLLHHHPLASGCSWLDQHSL
RNAAALDRALAAFPRVRHLLCGHIHQELDLNWGGRRMMATPSTCVQFKPHCDNFTLDTVS
PGWRWLDLHPDGTLTTEVCRLSGVKFHPDIASEGY
>A0A1V2BLH3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Raoultella terrigena|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLEAIHASQRQCDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYGTLQESGISPAKRVLLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAAEPERYTLLLLHHHPLASGCSWLDQHSL
RNAAALDRALAAFPRVRHLLCGHIHQELDLNWGGRRMMATPSTCVQFKPHCDNFTLDTVS
PGWRWLDLHPDGTLTTEVCRLSGVKFHPDIASEGY
>A0A654KWF9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter baumannii (strain MDR-ZJ06)|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIQQILKQHPEADAIIHT
GDLAQAPTPITYKRYINFMQTLGLPFFQTLGNHDNVDHFPLHNENHQQPVVVGLGNWRVI
MLNSAVKGKVDGHLSSEQLENLANLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFQNVKALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLNNDGSFETKVFRLENFKTRINTDISGY
>A0A653MNK5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microbacterium sp. 8M|TrEMBL
MTVQFGRYAPPTHTLVHLSDPHLLAGGAALGGRFDVDRTLARTLAAIENAVERPDAIVVT
GDLADLGEPDAYRRLRAAVEPVSERLGAPVIWVAGNHDERPALREHLLAAPPSEDPLTAV
WDLNGLRVIALDSTVPGWHHGDLDEAQRAWLAEQLATPAPHGTLLAMHHPPVPSHIPFFD
ILELRHQDELAEIVRGSDVRGILAGHLHYSLHATFAGIPVSVASATCYTMDVASPGDRVN
GMDAAQSFQLVHVRPETITHTVVPVVEATPVDTFSPEWVARMAQLTPQQRLEAFSRKPGR
>Q8BQB2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus musculus|TrEMBL
MLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVK
KLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIF
QERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFT
DLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHC
DIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDR
IQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVE
KSQVSTLRLFSMFLMSSTNCSFL
>A0A399ECL6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Calidithermus terrae|TrEMBL
MRVFAIADLHLSRAFPKPMTIFGPNWEGHPEAVFEEWRKVVGEDDLVIVAGDISWAMKLP
EALLDLRDLGELPGIKVLLRGNHDYWWPSITRLRQALPPRMHALQHDSLMFGGVAIAGSR
GWDAPGSRDFSAEDERIYKRELERLRLSLKTVQNHPYAHLILALHYPPYSVTGGPTGFTD
LLEEFRPDMVVYGHLHGADPARLPQSWDGIPLHFVSADMMRFRPKLILEAEGEER
>A0A2H6AU40|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR39|TrEMBL
MWLLHLSDLHLTVPGRLLWDSIDANSRLVQVVDHVRLHGPRPQVILITGDLVGEEEAEAY
AFLEAALAPLEAPVLAIPGNHDSRELLRERFAPALADTVEGPGLSFAVRFGCFELIALDT
LVPGEPGGRLGPEQRGFLAARLQAADRPVVIALHHPPAAVGMPYMDRMGLEDADAFGEIV
AARREKIAAVLAGHLHRPIFTAFCGVPLLIAPSTAFSCGPEMLVRESPPRFVLEPPAFCL
HHWVAGTGLVSHLMVAGHHPGPFRRRRAAEEGGHAGAEAADAAARTGDRPAADAAPAADD
GAGPGS
>A0A845SFK6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acerihabitans arboris|TrEMBL
MESLLTLPVANGAIIRILQITDTHLFAGEDEALLGVNTYRSYCAVLDAVEAERHHYDLVV
ATGDLAQDHSLEAYRHFARGITRLPAPCVWLPGNHDYQPAMVKVLEECGISPSKHILLGD
QWQLVLLDSQVFGVPHGELSDYQLEWLEKTLAMQPERYTLLLLHHHPFASGCIWLDQHSL
RNAHMLAAVLARFPRVTTLLCGHIHQELDVDWQGRRVLASPSTCVQFKPHCTNFTIDSVG
PGWRYLDLHPDGTLSTEVHRLAGDEYLPDTDSEGY
>A0A833S040|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Frieseomelitta varia|TrEMBL
MNRGRYVEEGQGIVHEILLVFPKDDQQMDILANTSRRLGWSVSAAKDMEKAVESFQDRGH
ELVIIDYRGQRSAEADMICRAIRSSPVYHNSVIIALVKKSFLMHGEKDKIVMLDLLETGF
SRFVNKISEKLLGYKTSEILGKSITDIVIYDNFILMEQHISKGREFEGNMNCKRKDNQTI
TISCRVIPYSISLKKPNYYIYIYDTTYLSENIELLSSAMQPRGTVVSQRKMSEIKSIEGR
RRSSIRKLHSLQLEAPITKVITLLSNAIMELENPETAAQIEKAIDILKTTELYEPTVRED
ADPLTTEFVEALLSSPKKARESRRSSVESARFFAERSVNDVPSLHMQIKGFKNPQEITDV
LEKCLEWDFDIFKLETLTESRPLLFLGMTIMNVYRVPARLGCDEKIVQKWLTIIEMNYKV
RNSYHNSTHAADVLQATARFMQSERLKLILEPLDEVAALIAAAAHDIDHPGRSSQHASID
FSQFLCNSNNKLAILYNDLSVLESHHAALTFKLSLSDDSVNIFQVSHRETILLTNFRSKG
QRDFTCIVILVEFGKGFIQTSSSNDHRHDPGHRDDEAFRTFGKVHECVQREDNGQPTHGR
NNGHLCLFCSSFEVDAVLFFVYPDAVDMSVVLQPENVVLVKRMMIKCADVSNPTRPLRFC
IEWARRIAEEYFNQCVFDVLRCLNLLQTDEEKKLRLPVLMPMFDRSTCSIPKSQIGFVDF
IINDMIEAWDAFIDMPEMVGYMRHNYDKWKEYNMSVVPLMFRDWWDDFDRPVSRLMDQHF
GRALNRDELLSRFSDLGLERPPLRSIFRDRYYRPWRNVARQASSGSSTIQIDSKNNFQVI
LDVQQFSPEEITVKTVGNDVIVEAKHEERQDEHGFVSRHFVRRYVLPPSHDVINITSSLS
SDGVLTITAPKKEETPSGTERVIEITKTGMPASKPVQVETATEEK
>A0A829L647|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli 907889|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>V0SWG8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli 907672|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A1E3WKQ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio scophthalmi|TrEMBL
MKVTSSSSAKDTIKLVQITDTHLFAAEDGSLLSVNTNDSFSAVVEAVTLQGFDFDAILAT
GDISQDHSDVSYQRFAQGIEPLKQPCFWLPGNHDYKPSMGSVLPSTQIVQAEHALLGEHW
QMILLDSQVEGVPHGRLSQQQLDLLDEQLRLHPKRHSLVLLHHHPILVGSAWLDQHTLKD
AEQFWQVVEKHDNVRAILCGHVHQDMQKVRSGATVISTPSTCVQFKPNSDDFALDTCSPG
WRELTLYADGQFETHVQRLAGGLFLPNFDSSGY
>A0A6P4IQB6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila kikkawai|TrEMBL
MRNCLPKFSHVFRRKSKSSALGQENPTEPDSDSEPYVAAVAPPAAATMAISQPRRDSPNE
RPMPDDDSASSRLISSPHLDSKTNLDLDSPAAGGQGSCPEMKLETISATAPPVAISLPFG
GRNSSKTPEEMELEYEASVAAEGRDIMTPLRRNTRPLSLAFGSGRSTGVGAGGVAGTGVM
QPEIVEVIRSLDVPALLLNSLSLEADPREPGAELECDSSEETVVLRRKVNCLERKTRSLY
ERRLPKVPKLHLQVAAKKTSEEEEFRTFQRNLMDLKYPTVLPPNPQLKALLVFHKADSIC
EAVTAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSAKNLDAEHIARTIR
HTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRP
HNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLNMRLDEIISKPLADIFVSD
LSTISEQGKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQMDF
IATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKENCSADEA
RLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTVGPSVYSSRRSSNDSIIRTGS
STRTATIVPAKMKANPIIMELLEESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFAT
LNIDENVCKAWLAVMEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDMLVMDRMDEAT
ALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLGDDKINIFKN
LDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPREQHSQTEEETSILMRRML
IKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRATCSIPKSQIGF
IEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLADIMAKQPPVGKMANSK
>A0A221JZW5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sulfitobacter pseudonitzschiae|TrEMBL
MTRIAIVTDIHHGAPSHTKRGDTALDLLGQFAGWANTQKPDLVLDLGDRISDIDTQTDMR
LEREVAEVFAQIDAPVQHICGNHDRDHLSVAENEQILGTALGHEVIDLGDWQLLLWRADA
KIHRDTPRVGFDLPEPDLLWLSHTLQRAEKPTLVASHVPCSGHSQTGNYYFQRNASLSTY
PQADRVRDVLAQARVPLACIAGHVHWNTVTTVNGTPHITQQSLTESFTTAGEPARAWGML
ELGDTIHWQVFGDDPFEARLTPTNQRWTAPLAPFVSKLAAE
>A0A6P4IPD1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila kikkawai|TrEMBL
MRNCLPKFSHVFRRKSKSSALGQENPTEPDSDSEPYVAAVAPPAAATMAISQPRRDSPNE
RPMPDDDSASSRLISSPHLDSKTNLDLDSPAAGGQGSCPEMKLETISATAPPVAISLPFG
GRNSSKTPEEMELEYEASVAAEGRDIMTPLRRNTRPLSLAFGSGRSTGVGAGGVAGTGVM
QPEIVEVIRSLDVPALLLNSLSLEADPREPGAELECDSSEETVVLRRKVNCLERKTRSLY
ERRLPKVPKLHLQVAAKKTSEEEEFRTFQRNLMDLKYPTVLPPNPQLKALLVFHKADSIC
EAVTAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSAKNLDAEHIARTIR
HTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRP
HNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLNMRLDEIISKPLADIFVSD
LSTISEQGKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQMDF
IATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQV
QENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTVGPSVYSSRRSS
NDSIIRTGSSTRTATIVPAKMKANPIIMELLEESLSWDFDIFKLEEITDYHPLLYLGMEM
FRRFDVFATLNIDENVCKAWLAVMEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDML
VMDRMDEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLG
DDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPREQHSQTEEE
TSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRATC
SIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLADIMAKQP
PVGKMANSK
>A0A5E4K3S4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKTKKYIFLGKTIFFPEQGILAVGDLHLGYEYKMQQSGVLVPEAQVEEIKTELKEIFEEI
KEKGFKLKKMVFIGDIKHSFSYEWKEKNYFREILTFLKNYIDDKNIILIKGNHDTIDYSF
SDRLKDYFIDGEIAFSHGHEAFPEIFDKKIKTIVIGHLHPSIILSDKQNIKREKYKCFLV
GKFRKKEIIILPSFLATIEGTTINSIKDEYEDYF
>A0A5E4JHN5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MNVLFFGDVHGDAKKAELLVKKSKDADLMVCCGDLSIMGEGFGDIISILDKSGKKMLIIP
GNNETPTFVEEALEDYENIISIQEDVYEDNGIRFLGIGGGTVSPWNTPYELTDDEFKKML
SKNYEKVTVLVSHTPPKNTVLDLVGGGMHVGSFEVGKWIEEHQPKYACFGHIHEAAGKEM
KIGKTLCFNPGPEGRIIKI
>A0A5E4K936|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKLLALADLHGDYSHIEAIREKAGFFDAVLIAGDITNFGPDEHAIELFRMFREPVLVVPG
NCDNPSILKILDERAINLHNSVHACEGLTFIGLGGSNPTPFNTPFELSEKKIGEYIGLLL
SGLEGRIVLLSHAPPRNTTDRLPRGNAGSEAIARYLGRFDLVVCGHIHEARGYVKVNGTL
VVNPGMASKGQAAIITVQNKITVEFIEA
>A0A5E4I6K7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKILAVADIHGSQYRLNLVLKNVKAYSPDLVVLCGDITQFGPGELATNFLNQIPVKTFAI
PGNIDTFDVDQGIIASNAIYLHLKRVVIQGIPFVGIGREIPSPLTDITIINDGEKKSLMN
VLDKTSVLVTHVPPFKLQDKIFIGSHGGSKKLRNLIDTCKPRFVLCGHIHEDPGVTQLMN
MTVVNCSLGKRTEGAIVEINDTIKVTILD
>A0A379SPD0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. arizonae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYGALQEAGISPAKHVLIGE
EWQILLLDSQVFGVPHGELSEFQLEWLERKLANAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSLLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELLANGVLETEVHRLQDTRFRPDTASEGY
>A0A7X2VA65|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter sp|TrEMBL
MTTKEKNRPLRVLQLTDPHLMARADGDLLGVRTRESLQAVIAEVLKVHGQPDLILATGDL
AQDGSVEAYRVFGESLKSFSCPSVWIAGNHDHIDNLLQVSREYNASDRHVIQGGWQFVML
DSSVPGKVFGALAESELAFLSETLEQHPDIPAVIALHHHPVDIGSDWMEKIGLTNRDAFW
QVLDRFPQVRIVLWGHIHQEHERERNGVQLLATPSTCIQFTSGSSKFSVEDLPPGYRWFE
FHDYGDFATEVRRAEDFQFELDQNSSGY
>A0A857SL64|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteus vulgaris|TrEMBL
MESQLELSVKQKNTVRILQITDTHLFANVEDTLLGINTYRSYHAVLNAIREQGLDVDLIV
ATGDLVQDQTFEAYQHFADGIATLVPPCVWLPGNHDYQPAMIDALNQAGILSAKQVLIGD
NWQMLLLDSQIQGVPHGELSDCQLDWLTRCLESQKYRDTIILLHHHPMPSGCTWLDQHSL
RNSQELAERLKDHSQVKMMLCGHIHQEMDEMWNGIRLLATPSTCIQFRPHCTNFTLDTVS
PGWRYLEMSLSSDEKGKIDTQVYRLEGTEFCPDLDADGY
>A0A6G6ZSX3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. BIOMIG1BAC|TrEMBL
MPSVSASPADDSVLLVQLSDSHLFAETDGVLLGMNTADSLQRVIDLVLAQQPQIDLLLAT
GDLSQDGSLESYQRFRQLSAQLPAPARWLPGNHDEPHVMQLATGDSVLLQQVVDIGNWRI
TLLDSSVPGSVPGFLQDDQLQLLERSLREAPQRHHLVCLHHHPVSIDCAWMEPIGLRNAQ
ALFEVIEGHPQVRALLWGHVHQEIDRMRGDVRLLASPSTCIQFEPRSDDFKVDERAPGYR
WLRLLADGRLETGVQRVEGYDFTIDYGSNGY
>A0A6P2RVH3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Burkholderia arboris|TrEMBL
MPHNNDLIWLHISDIHFHPKTSWRDNATRRELLDFLRAEFDNGLPRPHLVFCTGDIAFGE
TSGAPLSEQYKDAAQFFDDLLACCQLPKDRLFIVPGNHDVNRREISGDQQARLFEMAQTN
PLAHVDAINQRFADRTRDHRSAMERLKDYGAFVKEYRPELHREDLHLYAHTLEVNGYRVG
IAGFNSAWSCAGDEDDRHIWLASKWQFNHMAEGLRDAGLKIGLIHHPFDWLNSAEQHDAD
ANASTGLHFLLHGHTHTAWVRTSEACTQLAAGAVGADTPDQFGINLVHLDPRSGKGKVHL
FGYNRGWMIQPVPKHAPTAQWPFQSSVRLTPDLVAAPPGTDRTGSQSPATPTQAAGPAGE
ALYGRDKLLGQLVARLKDKSGLVLHGLSGNGKTTLIKALHGHAPFQGMQFVDVHGSRQIV
VGEFFRRFLGVLQNRREDPSPPSGKLEEQIAELRRQYPNAQPAFVWIDDAHLLMSGAQWC
NPELRVLLRAMSAAFPNWKWVYEFNDKPADGSFGSESPAFEIPGLDKAGLAELLANSAPP
DRKADWTYAGSDLKALFQWLGGGHGGAAHTLAAELLATVAREQGSTPMQVYRNLRKELID
RLDERLLGILHNEVLGTAERKLLKVIALYRRAIPQDHADGLEDGIGVQDAWQKLRGRGLL
PLDNNRDHYLHGFIASWVRQTQMGLRDSGLAIDYADAIDPAVADMHVLIARCWQRQIGRQ
REEINFQRANEAFYHLLCANELGAMEEWIGHLTGKEIGWSNEALWAIYHRRRDGGESIAR
QQEVLQLLVNIHPREHKALRFLGECLRVTSGDACDEALQAFERALELHPGFPPYLANLGK
ALLSRGKPGAEAFLRRFDEHQKRHPQAVDGHVDHIRADCLSLVGNAHEASRQRQQAIASD
TRDPVFYNDEAKYQLDHDNAPEALRLLDLAGDRQCADDYSDAMRIHTLERLGRGPEASVL
RMAKIDAGSSNPVFYADEARHQMVQGNLSGALDLLNLAHDRQSWDNYCEVIRRQIQEKTR
QGS
>A0A670JQQ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Podarcis muralis|TrEMBL
MKEQHSCVGTGHPPMAGYGRMAPLELAGSPVKRLRTEYSFPYLFAEEAYQKLASETLEEL
DWCLDQLETLQTRHSVSEMASNKVGQKPPPRSHLLPQLVRKRAMIFLEEWCNINAMANLI
SLLTADLIYTGRGKREGSI
>A0A2P7R1W0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Zobellella taiwanensis|TrEMBL
MLPTPRIQHGQTGLNKATTAPPVTLSARRPDGVVELMQITDTHLFSDPDGELLGIATWHS
SRAVVDAMKEEQAGCDAILATGDLSQDHSPESYRHFARLMAELTPPVFWLPGNHDDAPVM
QSELDAAGIGTAKHLLGEHWQVLLLDSQLHGKAHGSLGEAQLALLDQVLARYPRHHLLVA
VHHQAVPVGCAWLDQHNLRNAGELQARLGRHPASRVVLCGHVHQGFDEVRDGIRYLASPS
TCIQFKPLSDEFALDHTAPGWRALSLYPDGRLSTRVWRLPPDSFVPDFSARGY
>A0A7U7FXX4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia enterocolitica (type O:2) str. YE3094/96|TrEMBL
MESLFKLPMASEARVRVLQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGISRLPAPCVWLPGNHDFQPAMVDALANAGIAPSKHVLVGD
NWQILLLDSQVFGVPYGELSEYQLEWMERCLMAHPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLNWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGRLETEVRRLASDEFCPDMDSDGY
>A0A6H2H4H2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Polaromonas vacuolata|TrEMBL
MKIQLLSDLHLESNPHFFAKPVPGADLLVLAGDIGSYQSGSQLSSLGVADYGLARFSPLP
VSQGGAAWPTPVFFVPGNHEYDGQDFETAHLRLRETCQRLGLVWLEQQSLTHQGVRFIGS
TLWSDFDALAQPGKDKNGQTSLDKAIRAANFYLKKNHSTRAGQPLLAAELREHGLQSQAW
LSQALAVPFAGPTVVVTHFAPSLLSADPRYGMSPGTAGFCNALDNLLPQAQLWLHGHLHC
ANDYRSQGCRVVANPLGYARKNEQLAFQPDLLIEV
>A0A7K0D4F9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nocardia macrotermitis|TrEMBL
MLNARLRATWVANAASGAAAVTVGTPFRARSAYTLHRADHVRVQQDSIIASDLELVTVTD
TTAILTWTTRARDHAGRLRPAPADTEIRIAPADAAHPPRRYSLDSRPTAYHYAQIEGLEP
GRAYRFEAYSGGYRAAPARTLVTRRAGSPETTGVFTTLTPPPGTLLRTIALANDVHYGES
TSGLIVAGFPNGLRHDTHSHPEIMLDALLSDVRATDRGTDHLIVAGDMTDSGTLEQSSAV
RARLDSWGAAGRDYFVCRGNHDVSREADPWGSVFDARGRVAVSDVDGLRIIALDTTRPRG
SGGTLTAPQLSQLREALATEPDRPILMFGHHPVTSSAAVSNPAGPGFVLDRASAAALHAL
YRRAPGVFLHHTGHTHRNRVGRPDSPVNVEFLEGAAVKEYPGGYLLLRIYSGGYMVNFYK
TRAEQALRWSTRTRKQYFGLHPDHALGSLADRNHVVLRDFSGLR
>A0A485NLL9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lynx pardinus|TrEMBL
MSIIMKPRSRSTSSLRTTEAACFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRES
FLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRA
PSKRSPMCNQPSINKATITESE
>A0A4X2L3T2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vombatus ursinus|TrEMBL
MLFLTHDTPSVGTVPLHWLYPVPRMFSLFSPLSISFPDFLHDSAEILPSAGGLPGFPTST
RDLPLKLPLRSLLDTVICLFFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESF
LYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGAHH
IQVGTHHQVQPCSFFKKGN
>A0A2K6FGP4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Propithecus coquereli|TrEMBL
AFHFDVDNGTSVGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRN
SSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATIT
GKKDLGPILHMSRKKLCLPRVNTILSLILHCNMKTLKN
>A0A4X2M2B0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vombatus ursinus|TrEMBL
MLCLQPLTEYPFPYLFTEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKVRDNP
LVLLTFGITKSELLLCPVLCEYLAEEKGKGGMHMLSADG
>A0A402DEQ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcystis aeruginosa NIES-4285|TrEMBL
MNFRFAILSDPHIALPTTILNHSNRFHLVEVSIPALKIVLDHLITLNLDFLLIAGDLTQD
GEPENHRWLADCLATLPFPVYVVPGNHDVLSLTATENQIGLGDFPFYYQQFGYSDPEQIY
YQKEILPGVQLIGLNSNQFDEQGKQIGSLDAEQLHWLKQILPALKNDLVMVMIHHNVIEH
LPGQSNHELGKRYMLANAGELLDILEENGVKLLITGHLHVQDLAFARGIYEITTGSLVSY
PHPYRVLEYCENTVELAIKSFHLQNIPGWENLPAISRQWLGDRSYPFMMRLLTCHPLNLP
VSLAEELAPKLRNFWADVAQGDTIFDFSDFPPLARRYFYAFSAIDPLGNPHFIDNQAVIR
VC
>A0A7X8PNY2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonadales bacterium|TrEMBL
MAPRYFTPKSDDGTVRVLQLTDCHLFADDEKDLLGVNTAKSFEAVVNAIKEQHFDYDFIA
FTGDISQDYSVKSYQHFAKQISILEKPVFFLPGNHDDGPLMYRVFEDLGVNIAKNVITPK
WQFVFLNSEVYAVPHGWIQRKQLDYAAFCSNRSPEQHMCLLVHHMPMLVGSRWLDTQTMH
NFDEFNTYIHRINGVKAVVTGHIHQEFDETVRGIRYIATPSTSIQFTPKSNDFALDNLAP
GWRYLNFNPNGTVDTVVYRLKDNIFIPNTDVEGY
>A0A6J2UFZ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila lebanonensis|TrEMBL
MRNCLPKISSVFRVKSAARGENVGSGGKQRAASHSNESDCENETEQYVPAKTMVTTTKCD
QLADSDNEIQRQSDATILYIDDDNNHNTDNNDNNNKNNINNKNKGNNSDKTKAKISKGAS
NVADLNRHSSSLSASSESSETTISQVTMRPSIRPMDVRLVGGKSLDSASAEMLKQPLGVV
NCKTPEEMEREYEANVAAEGQDVMTPLPRSTRSLSMAAFGTASGRNMQPEIIEAIRNLDA
QALRLNNLTLEDKGGRNVQTTTSSPAATAGQCVQGDEECVILRGKAAHDVAVAAPSLGLY
ERRLPRVPKLTLMVGNKKQKQEKSKEKNKEKNKEKEKQQPCEFAEYKCCQRNLMDFKYPT
VLPPNPQLKALLVFHKSDNICEVITLACQRHQLDVTLVKSKEEALDTLHKSYATAECYHL
IMIDARSTKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCIAE
TTNLGVCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVMRIQYANRATER
LLNMRLDEIISKPLADIFVSDLSTITAQGKSIKEFDGILTVRRKNQDGIPMHVRVVPVAC
IGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLA
KLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIA
TDLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKANPIVMELLEESLSWDFD
IFKLEEITDYHPLLYLGMEMFRRFDVFATLSIDENVCKAWLAVIEAHYRKGNTYHNSTHA
ADVMQATGAFITQLANRDMVMERMEEATALIAAAAHDVDHPGRSSAFLSNSNNPLAILYN
DLTVLESHHAAVTFKLTLGDDKINIFKNLDKEAYKSARSTIIDMILATEMTRHFEHLAKF
VSVFGSDVEPRELMQAEEESSILMRRMLIKVADVSNPARPLPYCIEWSGRIAEEYFTQTD
EEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWDSFLDMPQLITHMQTNYAQW
KKFDEQGINTLADIKATQPPIVTHKLANSK
>A0A0A5HYV9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium sp. (strain ATCC 43367)|TrEMBL
MKVTSNSSDSSIKLLQITDTHLFEATDGSLLSVNTGESFKAVVNAIVEQECRFDALLATG
DISQDHSEASYQCFERGIEPLLKPCFWLPGNHDYKPNMTSVIPSPQIQQVDHVLLGEHWQ
MILLDSQVVGVPHGRLSDKQLALLDEKLAQYADRHTLVLLHHHPILVGSAWLDQHTLKDA
DDFWQVVQKHDNVNAVLCGHVHQDMNVMHHGVRVMATPSTCVQFKPNSDDFALDATSPGW
RELVLKADGQLETYVKRLPAGCFQPDFSSAGY
>A0A830ZYT3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia amylovora NBRC 12687 = CFBP 1232|TrEMBL
MDSLLKLPVASGSRVRILQITDTHLFAGKDETLLGVNTWASFDAVLEAVAAEQRHYDLIV
ATGDLAQDHSVEAYQHFAEGIARLSAPCVWLPGNHDYQPTMFSTLGASSIADQKQVLIGD
HWQAMLLDSQVFGVPHGELSEYQLEWLDRAMAAEPQRHTLILLHHHPLPSGCSWLDQHSL
RNPHMLDAVLQRYPRAKTLLCGHIHQELDLNWHGRRVLATPSTCVQFKPHCTNFTIDAEA
PGWRWLDLAADGHLETEVKRLNTRMFNPDLDSEGY
>A0A2U8IAT4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Fukatsuia symbiotica|TrEMBL
MVNGTKVRILQITDSHLFTDKNQTLLGVNTAESYHAVLAAIVMQQHHCDLIIASGDLAQT
PSVVAYQRFAAGVSELAAPCVWLPGNHDDQSVMVKVLADAGIVSAKQVMAGNDWQILLLD
SQVVGQSYGNLSEHQLLWLEHCLQAHPQRYALVTLHHHPLACGCSWLDQISLRNASQLAE
ILMRYPRVTTLLCGHIHQELEGDWYGRRLLASPSTSVQFKPNSLIFTLDNLAPGWRYIDL
QPDGSVATEVCRLADGEFCPDINSDGY
>A0A403LZX4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella dysenteriae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGMLTTEVHRLADTRFQPDTASEGY
>A0A443SLP4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Leptotrombidium deliense|TrEMBL
MPTNSTHFNVKAAQTLYSALDMCRDGIIITTANHQIEYMNRSMEKLLGYKLDEMIGKLTN
ELHKTDSQKNDIYDSINSQLQKGKEWEGTLLHIRKSGELLPLWSRIKPVDITNGTAEHLV
YVKECPYYAVEKMFSPEGEILPFNYGSIKGNRKASYDVKSLCSEGKISGLNRRHSFAKFH
AMTIEAPISKVINILMATQENSPVFVAQALDKVLDILRGSELYSPPITGFQQPNKEDDQV
TSDLFTGLIHSNKATGIRRMSHEQVVQKNSLGVPQTPTQLPSLTNIPPNIKNLLDSQLDW
EFNIIELEQVTNNRPLVWLGLSILSVYNVCATLNCDEVTLRNWLTVIESNYHDNPYHNST
HAADVMQATAYYLRKPRLKEIFDPLDEAICLLSAIVHDVDHPGKNSAFLCNSRHDLAVLY
NDISVLESHHAALAFKLTISDESVNIFKNLDRDTFKEVRQSIIDMVLATEMTKHFEHLSK
FVNVFSKPLSIEEAQCSQTETIMNDSTANTSDISSLATPENVVLIKRMLIKCADVSNPVR
PQKLCTVWAHRIADEYCNQTDEEKSRGLPVVMPAFDRQTCSIPKSQIGFIDYFANDMFEA
WDAFGEFPELLDYLHSNHVYWLSEEKRRVSGGSLQTAANN
>A1SA41|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)|TrEMBL
MLKEAVEYSLAEGEAARLVQITDPHLFASNDGQLLGVNTSQSLAAVLNTLNATHYPAHLM
LATGDISQDYTPDSYRNFVQAIEFLGLPCHYLPGNHDDPRVMNLHMQGPRVFGQQRILIG
NWHILMLDSTVRGKPGGHMGELQFSLIDQAIAAYPNHHTLLVMHHNPILMDCAWLDQHCM
DNGSDFLARVSAYPQVKGILWGHVHQAVDEVYATANGQLPLMATPSTCIQFKPKSPYFAL
DHLQPGYRLLELLSDGSIHTHVYRVPGNRFAPDHSSSGY
>A0A3N2RU73|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kluyvera ascorbata|TrEMBL
MESLLNLPLAGGASVRVLQITDTHLFAKKDETLLGVNTWESYHAVLQAIHASARDADLVV
ATGDLAQDHSSAAYQHFADGIASFSAPCVWLPGNHDFQPSMYSTLQDAGISPAKRVMVGE
HWQILLLDSQVFGVPHGELSDFQLEWLEKRLAEATERHTLLLLHHHPLPAGCSWLDQHSL
RNAASLDNVLVRYPRVKNLLCGHIHQELDVDWNGRRIMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHADGSLTTEVCRLAGCEFHPDTASEGY
>A0A668VMJ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oreochromis aureus|TrEMBL
CSCASSCVLHNNQEKGDRKKTCKNGPHLKPLYSLFPLSLRSFDSENGPSPGRSPMDSQAS
PGLVLHPSFPQSQRRESFLYRSDSDYDTSPKTMSRNSSINSEGHTEDMIVTPFAQVLASL
RTVRSNFTILANVTTPTNKSVSCCQTPLPPHLTCHDCLLRSQCVYANVSVSLIPWGNTLV
IMINQFMMTRQCSRNI
>A0A2S6TW98|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alphaproteobacteria bacterium MarineAlpha3_Bin3|TrEMBL
MIIAQITDTHLAAANAADPVFRARAENLRECIADINGLDPMPDAVIHTGDMTQHGQAAEF
AHARSLLAALEAPLYVIPGNRDGREGMVRAFAGDGYMMPDCAFVHYAVEEHPVRLVAVDS
LAADGSAKGDLCHDRLAALDATLAEAPAQPTALFMHHPPFDVPTAPDPFAYQRRRAGSDL
AAVVSRHPQVVRIFTGHMHRPWTATVGGVAASTVPSVAVDLRKGHYAPTMAGRPVYQVHR
FEGDWGFASETRLAGSGAISR
>A0A5E7BMZ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTSADSALLVQLSDSHLFAEAEETLLGMNTRDSLQKVIELVRAQQPQIDLMIAS
GDLSQDGSLESYQRFRDMTRQIDAPARWIPGNHDEPQVMAEAATQSQLLESVVDLGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWLAPIGLRNPE
ALFTVLDRFPQVRAVLWGHVHQEIDQLRKGVRLLASPSTCIQFEPGSEDFKVDTLAPGYR
WLRLLPDGQLETGVERVTGFSFQVDYGGPGY
>A0A5E6U0D9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTPADSALLVQLSDSHLFAEADGTLLGMNTRDSLQQVIELVRQQQPQIDLIIAS
GDLSQDGTLESYRQFRDLTRQLDAPARWIPGNHDEPQIMAKAAVQSALLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
GLFAVLDRFPQVRAVLWGHVHQEIDQVRNDVRLIASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPNGQIETGVERVTGFDYTVDYGSSGY
>A0A2D0K8Z6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus sp. KK7.4|TrEMBL
MESLLEIPVAKGATARILQITDMHLFANKGGSLLGINTYRSYHAVLDAILEQNIDIDLVV
ATGDLVQDQTPGAYQNFVEGIARLPAPCVWLPGNHDYQPAMVDVLAAAGISPSKQIFIGQ
HWQLIMLDSQVQGVPHGELTEYQLEWMSKCLDEHSDRQAIIMLHHHPVPSGCTWLDQHSL
RNAPALAECLKSKSQVKTILCGHIHQELDVMWNGIRVIATPSTCVQFKPHCTNFMLDTVA
PGWRYLELPVTGGGEAELQTQLYRLRSNEFCPDLDSDGY
>A0A2I8QL95|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacteriaceae bacterium ENNIH2|TrEMBL
MESLLNLPLAGGARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIQAQQRECDLIV
ATGDLAQDQTAAAYQHFAEGIARFGAPCVWLPGNHDFQPAMYTALQEAGISSSKRVITGD
NWQILLLDSQVFGVPHGELSEFQLDWLEKKLSASPERHTLLLLHHHPLPSGCSWLDQHSL
RNAAELDNVLARFPHVRYLLCGHIHQELDLNWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLYPDGSLQTEVCRLQCTRFNPDTASEGY
>A0A162SHU9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Daphnia magna|TrEMBL
MGCATSQLPLGGGSQRQRRHSSSANSSPPNNVTTVLPDNHHHHNDEKANRSVALATNNVI
SQQTQQQQALRIVRNPSNTDNRPSLENSTTGKYRRGNSSDQNSTSPTQLENGVRLSNDVR
FGAMRAPPEPLKVMLVFEREDAQSDAWLWACRKLASRCGGTEMSHSNSRSSHSSSSSNSH
EIHHQDVLVRTLQTELVQRKIAELEPNLIVIDRRSASRSREVDALCRWIRTQPGGNYPII
LAVVKRNLLEREESIVSSILHIGYDRCYPESGNLGSCLSELLMLEASELQSRQRLRLAEA
SMTVAAVTRELVTVTDGHFNIRYINPGVERLLGFTADEIVGKNMIELYRCEAGNNRYDIN
DAAQHVLTNKTKEWEGSCFVRRRTGDSVPLYTRMIAVHSTKTEQVATITKCSGYSIDIAS
TCTADKHSVTSHIRRGPSVSKFRVTFRLLSFRLYVAIVSQLLDSQRIRLGASYSNKTSQF
SDEAINETPDYVLLLQEPPPLFIDKSLSGDMGAYDFYPMPRSSLHSVRKASYDVRSVGSD
GAIIRRQSLARLHSMAIEGPITKVINIITAAQESSPNYISQALDKVLDILRSTELFAPHV
AEVKGRNEDPVTTDLVGALLLGQKQPGYIRRSSNETSLKSSHSQLYSRPLLPSLNNISIP
IQLREMLENDSQWDFDVIRLEKLTGKRPLVWLGMTIMTRFEVPRTLNCDEATLQNWLTVI
EANYHSTNTYHNSTHAADVLQSTAYFLQRNRIKALLDPLDLTACLIAAAIHDVDHPGKTR
VNIFKGLDRESYKVIRQSIIDMVLATEMTKHFEHLTKFINIFAKPFLRQDEDQYEPPEID
YASLNTQENIILVKRMLIKCADVSNPTRPLNMCIEWARRIAEEYFNQTAEEKAKGLPVVM
PQFDRQTCSIPKSQIGFTDYFVSDMFDAWDAYAEVPELLQHMKRNYQFWKEQETMGVTGL
PPEHIIPLTPTELVRKIEFETLAECKETVEPTEDK
>A0A849DYF0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacterales bacterium|TrEMBL
MNQFQWDTTQLKIAPKGTTPKVLQITAPHIFKDEAGCLLGLNTRRSLNAVLDDVYAYHRD
ADLILATGDISQDHSLESYNYFAKSMNKLGLPVAWVPGNHDISEFMAPALSGQNFVTNKR
ISIGEWDLILLDSSVEDAVFGQLGAQQLDFLEACLRAPVGKYAMPVLHHHPVDIGCDWMT
PIGLHDADAMFKIIDQFNHVKVILWGHIHQEFDIVKSGVRLLATPSSSVQFKPGSTEFSA
GTESPGYRTMKLQSNGSLSTAVHRIEHIEFTVDYTIKGY
>A0A7V8PNH1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium sp. CFBP8739|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKARQDAFDLIV
ATGDLAQDHTLEAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHSLSAVLDRYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDEVA
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A2T3LJT3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium sp. GB-1|TrEMBL
MQTYSLPQTNPDSVVLLQITDTHLFANESGALLGVATQQSFHAVLNAVDASTRKFDAIVA
TGDISQDHTPDSYQRFAEGIARWEQPCFWLPGNHDYQPTMASILPSEQIKDSEQILVGDH
WQVVLLDSQVAGVPHGELSHHQLALLDHALSLHPERHALVLLHHHPLPAGSAWLDQHQLH
NSDALWQVIDKHPQVKAILCGHIHQELDRIHRDVRVLATPSTCIQFLPDSDDFALDQVTP
GWRYLELTATGDIITHVERLEGDVFQPTFDSAGY
>A0A4V0II16|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinobacillus indolicus|TrEMBL
MDDSYTFPLKSPIVRILQITDPHLFASDDGELLGVNTTQSFQAVLNAIEQDLFDYDFILA
TGDLVQDHNREAYHRFAKMVKPLAKPIFWVEGNHDLQPQMSNALSLYAQMQPEKHILAGD
FWQVILLDSHIEGVPGGALSTSQLDFLKAKLEAYPERYSLIVLHHNILPTNSAWLDQHSL
ANADQLAEILKPYPRAKAILHGHIHQEVDKLWKGYRVLATPSTCIQFKPNCDNFTLDPVP
QGWREICLNLDGSIDTRVKRLDCNDFLPNFNALGY
>A0A443U813|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSAPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHPNGTLTTEVCRLTGAQFRPDTASEGY
>A0A6P4EFX8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila rhopaloa|TrEMBL
MRNCLPKFSKVFRRKSSAKSSASAGRENPSNDPDSDTEPYGIAAAPAFISTSHQCGDNRN
ERPLADDDSGRSRLISAAHLDLDLDSDSKSPAMATTTTMTTNGGIRPKSEGSRPEMKVET
ISAAAAPTPGPVAISLPFVGRNSSKTPEEMELEYEANVEAESRDIMTPLRRNTRPLSVAF
AGGRNALQPEIVEAIRSLDVPALLLNNLSLEGVRDLGGDSGGCTAAEISPGHQDLEDSVV
LRRKANCLERRAHSLYERRLPKVPKLHLLVAGGGGGGGGKKPTEEEEELRTFQRNLMDLK
YPTVLPPNPPLKALLVFHKSDSICEAITAACQRHQLDVTLVKSKEEALDTLQKSYATAQC
YHLIIIDARSTKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRC
VAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRA
TERLLNMRLDEIISKQLEDIFVSDLSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVP
VACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRT
SLAKLTSLPLEAPITKENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGA
LLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKSNPIIMELLDESLSWDFDIFKLEE
ITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQA
TGAFITQLTNKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVL
ENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFG
GEEPREHNCQTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQR
HLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDE
QGVNTLAEIMAKQPPVGKMANSK
>E1W4X8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus parainfluenzae (strain T3T1)|TrEMBL
MNNRFEYEPASEVVKLLQITDPHLFRDTSKDLLGINTHESFSQVLKEIQLEPFEYDVVLA
TGDLVQDSSDEGYLRFVEMVKPLNKSVFWLPGNHDFQPKMVEHLSQSPINASKHLLLGKH
WQVILLDSQVSGVPHGELSAYQLDWLKTKLAENPARHSLVVLHHHLLPTNSAWLDQHNLR
NAHGFSAVLAQFNNVKGILYGHIHQQVDGYWQGYQTMATPATCIQFKPDSNHFALDTLQP
GWREIELHPDGRIETRVKRIKQKTFLPNMEEEGY
>A0A6M1ZY27|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Anoxychlamydiales bacterium|TrEMBL
MIKIAHISDLHFSKLSFHPKIFFSKRFVGMTNLFFNRKRKYKTNKLSNLPVLFKKEDIDY
AFISGDITTTSHESEFILGKNFVDSILQNDIKTYLIPGNHDCYTKSAYKKKLFYKYFENE
SLRNNNIESLPLENNWHYIGLDCSISTFLLSSSGCFSKDLENKLNKLLNTLEDKKVILVN
HFPASRITTYRKRLIRDSFLKELLKKHKNIKLYLYGHTHKYKIEKEKDLPYMICSGCASH
IDGTFNIFSLNDNSIEVNKYAFKNDTWIKEKDQILEI
>A0A1S3R8E7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmo salar|TrEMBL
MSQRKLTRQMNLWETPEGLTTPSLTPTSPYVTSANSPVSPDHDHTRGHGNSVFFRRMKLN
RSIERRRASHSHLPLSFDSENGPSPGRSPMDSQASPVLGLHPSFTTEGCRSRGERRESFL
YRSDSDYDMSPKTMSRNSSINSEGHAEDLIVTPFAQVLASLRTVRSNFTILANVTTPTNK
RSPVTSQPTVPQATLSDETYQQMARETLAELDWCLDQLETIQTHRSVGDMASNKVLPLLP
VPLPFTITTTSPHHHYHYHYLTLEVLLH
>A0A542BUU5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia fonticola|TrEMBL
MESLFRLPVASGAKVRILQITDTHLFAGNHETLLGINTYSSYHAVLDAVIAQQRDYDLIV
ATGDLAQDHSPAAYRHFAEGISRLPAPCVWLPGNHDFQPAMVDALAAAGISPSKQVLLGE
HWQILLLDSQVFGVPHGELSEYQLEWMERCLQAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLAAILLRYPKVNTLLCGHIHQELDLDWHGRRLLASPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A1S3R971|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmo salar|TrEMBL
MGVVEAIDPASPSPCPSPVPGGYRLPHSSTSYSQLQGRGGGPDLELDLGAAAGGVLEGSG
TAAERRTPLVDLFCETCSRPWLIGWWDQFKRMLNRELSHLSEMSRSGNQVSEYISTTFLD
KQNEVEIPSPTLRERERDKPMCHISGVKKLTHSSSLSINTTMPRFGVKTEQEDALARELD
DLNKWGLNIFRLAEFSNNRPLSCIMFAIFQERDLLKTFRIPVDTFVTYVMTLEDHYHANV
AYHNSLHAADVTQSTHVLLSTPALDVRTTFHHTLSLCLTTANLKHTAAL
>A0A6M2AE10|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Anoxychlamydiales bacterium|TrEMBL
MIKIAHISDLHFSKVSFFPIALKRFVGVTNLLINRRKSYIEDHLYKLPTLLKSLDIDHIF
ITGDLTSTSLEKEFEKAKDFIDLFDKKNKFFIIPGNHDTYTKKAYKDELFYQFFKKTNIS
KMIKSNIQIHELSDKWVYIGLDTTVPTSLFSCSGLFSKELENSLIETLDKIPKDTNIILT
NHFPLFLRVEKRNGLNRRKHLLAILKKYKNIKLYLYGHTHKWTITKKENYPYMICSGCSS
HKKKASFNTLQIEDNKCIVTSYSLKNNNWQKDSDKILSF
>A0A8F2UWD1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Bovismorbificans str. Sal610|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRKLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A7I6SZJ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella sp. WP7-S18-CRE-02|TrEMBL
MESLLNLPLAGGASVRVLQITDTHLFAEKNETLLGVNTWESYHAVLQAIHASARDVDLVV
ATGDLAQDHSAAAYQHFAEGIASFTAPCVWLPGNHDFQPSMYSTLQDAGISPAKRVLVGE
HWQILLLDSQVFGVPHGELSDFQLEWLEKRLAEAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAASLDTVLVRYPRVKHLLCGHIHQELDVEWNGRRIMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHADGSLTTDVCRLAGVKFHPDTASEGY
>A0A6E8VSL7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles coluzzii|TrEMBL
MDISKVLIRQLSAREWRRFVAFRSLPADSIDPAFRQQILADYDVHFYEYGELAASSAQEV
VSADTVTFAVGEPTAGSSRPQQRWPEGSDGKQRQLVESVVESASQEDVQDTILPTLSEEE
AIFIERLVSDLKFPNLLPPNPVIKILIAFCKNDPVFEALVNASHRLSLEPTFVKSAESAI
DAFQNPSSGGHHIIIVDARYPRTIEAEALGRSIRNSKGSQHTTMVAVVKKSVFEKDDTAV
ISLLDVGYNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQALYTALHRSREAVIITD
DTLRAQYANRASERVLNMKLDEIVGRSLSDLVTADISNILSHTSRYKDYDGYLTTRRKSQ
ESSQIHVRAVPVSCIGRNPTHLVLILESSSSALVSTNAIGEALQTLPQGKEVPRGSLHSI
RRGSFDVRSIASDGLRRTSLAKLSSLPLEAPITKVLSLLAQVQENCSLDEAKLLDRVMEF
LKREGLYSPQMKEIRTEDPVATDLIGALLTQGPTNILSSRRSSNDSIIRGGGRPSTGSIV
FNKTKESSQLSDLLQTALDWDFEIFKLEDLTEKRPLVCLGLELFRRFDVYNTFNCDEMTF
KLWLIEMEKHYHSENTYHNSTHAADVMQATAVYLQQLSNRELKIMDRMDEATALIAAATH
DIDHPGRSSAFLCNSDNTLALLYNDICVLESHHAATTFRLTLGDDKINIFKHLDRDMYKL
ARSIIVDMILATEMTRHFEHLAKFVSVFGTDVESKDPLPPDNDDNQILVRRMLIKCADVS
NPTRPLKFCVEWARRIAEEYFMQTDEEKRKNLPIVMPMFDRTTCSISKSQIGFIEYIIHD
MMDAWNSFIEMPEIIRYMEFNYSQWKLFEEQGINTLSDIKRKQMSLTEDTASSISLEEKF
>A0A644WXT1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MALYAISDLHLAFTTDKPMDIFGSKWLKHDEKIKENWINKITDEDMVLIAGDISWSMRAN
ESKVDLDWIDKLPGKKIISKGNHDYWWSGISKLNNMYENTKFLQNNFYTYEDYAICGSRG
WILEGSDKFTEKDKKIFHRELIRLRLSLDKAKEDGYEKIIVMIHYPPMNEKREESAFTEL
FKEYNVEKVIYGHLHGPSLSNVVNEEHEGIEYIMTSCDFLNFDPKRIV
>A0A644VRL9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MEKWKIIIVLISVVLASCFHDLDEAGAVHSEYNANERFEMSQQWNNTHPFQVILLPDSAY
SVLFCGDTHIGTYAKFSQVLDAAKSPSAAALVVAGDITRGHPESYDTLETLMNSIDSVNW
FFTAGNHDLYFGGWDEYYPRFGSSAYYFIVSTPAGNDLFLILDSGSGTLGNLQLDWLSET
LESFGSSARHITLVTHLNVFKDGMGLTSGLPMEEVNVLLDLCAQYEINYVISGHDHTRYE
SELGPTRYIIMDQCHDEEENSSYLEIKYDNSSCVHEFHNIE
>A0A854FIP3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salinivibrio kushneri|TrEMBL
MQSCQIDNADGDCIRLLQITDTHLFASEQGSLLGINTLRSYHAVLDAISATDPTFDAIIA
TGDLSQDHSALSYRRFVDGISRWSQPCFWLPGNHDYQPEMSAVLQSNTLRSCSQVLLGEH
WQMVLLDSQVAGVPHGELSQAQLNLLDTHLSAHPERHALVLLHHHPLDAGSTWLDQHKLA
NREAFWQVMARHPQAKIVVCGHIHQALDVGYQGTRVMAAPSTCIQFMPDSHDFALDNQNP
GWRWLELYDDGRVDTQVVRITGQHFRPDFDSSGY
>A0A3Q8GGT1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurellaceae bacterium 12565|TrEMBL
MDAKRMHEYIKLPVTGVIKLLQITDPHLFSNPEETLLNVKTVKSFSAVIEQINKQAKQYF
DLVLATGDLIQDNNIAGYHYFAQITNSLNSPIVWLEGNHDVQPSMSEILAQYKHILPHKQ
ILLGEQWQLLMLNTQVVGMPYGELSYSQLKWLEEKLAQYPQRFTLVALHHNILPTNSAWL
DQHSLKNSNELSEIFAKFKNVKAIVHGHIHQQVDDIWHGIPIYATPSTCIQFKPNCDQFT
LDLQPQGWREIELHENGTIETVVKRLNSNDFLPNVNAIGY
>A0A8E0FPN6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli 97.0246|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPASCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A8C3NLK5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Geospiza parvula|TrEMBL
MREQRPCPGSGRRRMGALALPVSPVRRLRTERAFPCLFAEEAYQKLASETMEELDWCLDQ
LETLQTRHSVSEMASNKVGAHGLGPAAPLPPERGPGSRQPGLRWVGGGRRGQGAGAAPGG
ET
>A0A5P9NES3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Halioglobus maricola|TrEMBL
MTNPVSIANVQPATDVVRVVQLTDVHLCQQRGGTLLGMNTDESLQTVIRKVLRERDQIDL
VLGTGDLSDRGALEAYERLETYFEALPAPHFWLPGNHDDRGQMLAAARSDDRLIGEIRAG
NWQILMLDSQIPREVGGRLGAAELARLEQALGRAESAGLHSLLCLHHQPVSIGSAWIDQQ
MVEDAAAFWALIERFNCVRGVLWGHVHQEIEQERGPVRLMASPSTCVQFAPESVEFQADG
MPPGYRWLDLHSDGRIDSAVSRIEEELYVDLESDGYLD
>A0A746XAR3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella typhi|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGE
>A0A7C7CBJ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chromatiaceae bacterium|TrEMBL
MRTLPNPHPGIPLKILQITDCHQFADADTTLHGCNTRSSFESVMILAQEQHWPPDCILAT
GDLSHDGSEASYRYLLDHFERLGIPTFCLPGNHDEGTMLDAILHGDVVASHSAVDLGEWR
ILMLDSSIVGSEGGHLGKAALDMVTRSLSSSQGRHVLICLHHNLVPTCTDWLDTMTVDNA
DALFAITRGHSNVKAILWGHIHQKFEATKDGVALLGSPSTCFQFLPNSAEFQLDTRPPGY
RWLLLHTDGHIDTGIERIAAETQSLAQAE
>A0A7C1Q8T3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Halopseudomonas sabulinigri|TrEMBL
MSLAESAGTDYVCILQLTDSHLFAGDSGDLLGLDTLDSLNSVIDLVLDEISRMDLVLATG
DITQDGSEDAYRRFIAASLRLPAPCHWIPGNHDNAVLMRQLGAASGLSRDWVDIGNWRIV
LLDSSVSGSVAGRLADNQLQRLDDALATAGERHILVCLHHHPVDIGCDWMQPIGLQNADA
LFSRFTEQTAVKAVLWGHVHQEFDGKREGVRLLASPSTCVQFAADSEDFATDTLAPGYRW
LRLYDDGRIETEVSRLPPGSYLPEPGASGY
>A0A1B9PF43|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aliivibrio fischeri|TrEMBL
MLSETLLNEESDSIRLLQITDTHLFAPEDGALLGVPTRKSFQSVVEQVLQRTPDFDAILA
TGDISQDHTVESYQHFVKGITPLKKPCFWLPGNHDYKPSMGGVLPSPQISACEHLLIGQH
WQVIILDSQVVGVPHGALSDEQLTLLDNALSQHPQRHSLVLLHHHPLPAGSAWLDQHQLK
ESDQFWSVLAKHRNVNGIVCGHIHQELDRIVNGVRLLATPSTCVQFLPDSDDFALDSQAP
GWRTLDLLPNGDIETQVYRLKDCDFSADSEAGGY
>A0A2T1IYY1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter radioresistens|TrEMBL
MIVSHSMEHRDTWVIIQITDTHLMGQAEKEFVQMNPEQSFHAVIQQILLQHPHIDAIIHT
GDLAQEPEHITYQRYLSYMQGLGIPFFQVPGNHDDLDYFPFQQSYHEPGIVELGNWCLFL
LNSAVDGRVDGHISQTQLKALEQQLQQHAHQHVLIACHHHPFEMRSRWIDQHKLKNTPEL
TEILAQHSNIQAVICGHVHQDSIHIWNNIQFLSTPSTSVQFKPLSDQFALDEQAPGYRIL
KLHSSGQLDTQVHRLKDFHHRIETEISGY
>A0A8F9ISU4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O139:H1|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A6J5DNM8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Burkholderia paludis|TrEMBL
MSSSTPTRPSRRKALQCMAFGGLGTLFTLSGGILTPFDLALAQTGDARPADAGRPLFVQI
SDTHIGFNKEANPDVAATLRQTIELVNAMPAMPALAIHTGDITHLSKPEEFDRASQLLSA
LRVPELHTVPGEHDVTDGSGAEYFGRFGKASDNRGYYSFDHAGVHFIGLVNVMHFKPNGL
GSFGDDQLAWLARDLEGRTSSTPIVVFSHMPMWTVYEPWGWGTGDAPQTMALLRRFGSVT
VLNGHIHQIVSKVEGNVTFHTARSTAFPQPTAGNGPGPVPLTVPRDRLPAMLGVTTVEFA
GHPAASALHDATLA
>A0A6I9KY54|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Peromyscus maniculatus bairdii|TrEMBL
MGCSPSIHSSDNRAANHSVEDRGAPGPAPPRSRQRRRSTASGSGRVRLVEPQPRNGGASK
VSETDVQFGPMRFHQDQLQVLLVFTKEDNQCNGFHRACEKAGFKCTVTKEVQAVLTCFLE
KIHDIIIIDHRNPQKLDAEALCRSIRSSKLSENTVIVGVVRRGDKEEVSLMPFIAAGFTR
RYIENPNVMACYNELLQLAFGEVRSQMKLRACNSVFTALEKSQEAIEITSEDHIIQYANP
AFETTMGYQSGELIGKELAQVPINEKKGDLLDAINSCITIGKEWQGVYHTQKKNGDNIQQ
NVKIIPVIGQGGKIRHYVSIIRVCNGSDKVETVTESVPMNSQADNQAGKHKERRKISIDA
KAVSSKASEVTNQRRHSSLARIHSMMIEAPITKIINIINTAQENSPMPVTEALNRVLEIL
RTTELYSPQFNAEDDPHAADLVGGLLSDGLRRFSGNEYVLATKNLQPSSSSIPTPISLND
IPPRIAMAIENEEQWDFDIFELEAATQKRPLIYLGLKTFARFGICEFLQCSEATLRSWFQ
IIEANYHSSNPYHNSTHSADVLHATAYFLSRNKIKETLDRIDEVAALIAAAIHDVDHPGR
TSSFLCNSGNELAVLYNDTAVLESHHAALAFQLTLENDKCNIFKNMERNDYRTLRQCIID
MVLATEMTKHFEHVNKFMNSITKPLKTQGSEKTVLSPEALSTPENRTLIKRMLIKCADVS
NPCRRLEHCIEWAARISEEYFSQTDEEKQLDLPVMMPVFDRNTCSIPKSQISFIDYFITD
MFDAWDTFIGLPDLMQHLDNNFRYWKGLDEKKLCSLRPPPE
>A0A2T5EM81|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIKPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAVLCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTQVRRLPNGQFSPDFDAGGY
>A0A0M2KDJ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia tracheiphila|TrEMBL
MDSLLKIPAQRGTGIRILQITDSHLFAGKHETLLGVNTWASFDAVLQAISASKQPFDLIV
ATGDLAQDHSVEAYQHFAEGIAHLSAPCVWLPGNHDFQPVMFSTLAETNITDAKHVIVGA
HWQIVLLDTQVFGVPYGELSEYQLEWLDNTLARQSERHSLVLLHHHPVPSGCNWLDQHSL
RNSSMLEAVLQRYPLASTLLCGHIHQELDLNWNGRRLLATPSTCVQFKPHCTNFTIDSET
PGWRWLELYEDGRVETGVERLQTRAFSPDLDAEGY
>A0A1M5IVU6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium carotovorum|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKARQDAFDLIV
ATGDLAQDHTLQAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSAVLDRYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A1B9Q4B9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio lentus|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSHNFDYQAILA
TGDISQDHSAESYQKFESGIQPLAKPCYWLPGNHDFKPNMGSVLPSPQIQCVDHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLSEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAVLCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTEVRRLPHGQFLPDFAAGGY
>A0A2X3E6Z8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pneumoniae|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFLGD
RWQILLLDSQVFGVPHGELSDFQLEWIEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A6J1Q3X0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Temnothorax curvispinosus|TrEMBL
MGCKISILECMRGKVEQEKSISSATSSSLVTSDTTETDKNQDSLYLAFGKSHFIEEDDGK
VAQRKTDALDIVAEKDEKTPFQDSTLDENGDYLTIKGPQDLSNYLLTTNVPSIVKILLVF
SKDDPQLDILANTARRLGWSVSVAKDAEKAIELFQNRAHELVIIDHRGHHAAEGDAICRA
IRSSPVYHNSVIIALVKKSYFMLDEKDHIVALNLLETGFSRALIECSHEGILINELVGIY
TSSLLPRTQLAAAHALYLALDRCRDMVHVTNDKNIVQFLNKVSEKLLGYKTEEMMGRNLS
EIVFYENSALMEQQLAKGREFEGNMNCKRKNNQMITINCRIIPFCITLKKPSHYIYVYDT
TYLSENSAPISPASSPLHPPLKTSILSNARKSSDVRSGVSEGRRRSSLQKLHTLQLEAPI
TKVITLLSNAVTDTTNPETAAQIDKAIDILKTTELYVPHLKEDRAMYSDPVATDLVGALL
ASPRTAWESRRSSSDSARLSTIKAIAYPANSRVQVKNFRGPQELMDILDNSLDWNFEIFK
LEVLTEKRPLVFLGLTIMNLYQVPATLHCDEKTLQNWLAIIEHSYNAENSYHNSTHAADV
MQATARFMQSKRLKEILEPLDEVAALIAAAAHDIDHPGRSSQFLCNANSRLAILYNDLSV
LESHHAALTFKLSLSDDSVNIFKNLDRDAYKLLRQNVIDMILATEMTKHFEHLAKFMNVC
SARIGDGQETYSDSLDMSVVLQPDNVILVKRMMIKCADVSNPTRPLKCCVEWARRIAEEY
FNQTDEEKKLKMPVVMPMFDRMTCSIPKSQIGFVDYIINDMIEAWDVFIDMPEIVGYMRH
NYEKWKEYNEQGISTLQDVEKLQQHPEMQIPRLS
>A0A3E1ZV31|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Leclercia adecarboxylata|TrEMBL
MESLLNLTVAGGAPVRVLQITDTHLFANKHETLLGVNTWESYQAVLEAIHAQNRQCDLIV
ATGDLAQDQTSAAYQHFAEGIASFNAPCVWLPGNHDFQPSMYSALQDAGISPAKRVHSGD
SWQILLLDSQVFGVPHGELSDFQLEWLEARLEAEPDRHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDQVLEKFPRVKHLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLHADGSVTTEVCRLQGTQFRPDTASEGY
>A0A750D3D3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPKRQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2I1THI9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Veillonella parvula|TrEMBL
MKVFAIGDLHLSGNPPTKPMDIFGPHWNDHWARIKEHWNANVSDEDIVFLVGDMSWALRL
EEAACDLQEIASLPGKKYMIRGNHDYWWASANKMHNLMGDAITFIQGHGTAELIQTEEGP
RLIAFGGTRAYLCPGDSHFSPETDQSIYDRELMRTEAALQEMDKAIHKVLEELRTETNVT
DMTCSKKSYSSTPDSIIDIENIPVTKLLLLHYPPFNESNAPSGFTDLLEQYKVDICIFGH
LHDQISFNRIPKEFSTTKLELVSADYLDFKLKQII
>A0A3T3IH73|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella dublin|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A8B9LB43|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Astyanax mexicanus|TrEMBL
MAPIKRLKTDHPLPCLPPEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKVGWR
LIAHTCRASTQNMDMLHVACEIYLSTPV
>K8CU98|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cronobacter sakazakii 696|TrEMBL
MESLLNLPVAGGASVRILQITDTHLFAGKNDTLLGVNTWESYQAVLAELHAEQRECDLIV
ATGDLAQDHTPEAYEHFATGIASLPAPCVWLPGNHDFQPAMYSTLQDAGISPAKRVFAGD
NWQVLLLDSQVFGVPHGELSDYQLEWLERMLQAAPERHTLLLLHHHPLPSGCGWLDQHSL
RNAQALDDVLNHYPQVKHLLCGHIHQELDLDWNGRRLMATPSTCVQFKPHCAGFTLDTVA
PGWRWLNLHPDGSLTTEVCRLEGAQFRPDTASEGY
>A0A3A6UF93|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Parashewanella spongiae|TrEMBL
MVRDAAIYYPKKDSNNICLMQMTDTHLFADPDGQLLGVNTANSMQAVVDLMSLKKHEADV
LLATGDISQDYTSESYQRFNKCSEALALPCHYLPGNHDEWQLMQQHMIAKHIKPQRQIVF
DEWQVLLLNSTIAKKPAGFLPELEFQFIQKAIEQYPEKHVLICLHHHPLKINCDWLDRHW
LTNGDEFLQRIGRYAQVRGVLWGHIHQEFDDTHRGEHHDISLMATPSTCIQFTPQSDHFA
VDGLQPGYRLLHLHANGSIVTQVHRVVGDRFTPENEVSGY
>A0A653SV79|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bosea sp. 62|TrEMBL
MLIAHITDLHIRPLGKPAYRVSETNALTERALDVVAALRPQPDALVITGDLTDCGLAEEY
GLLANLLERVEVPVLLLPGNHDRRETLTAGLKLGPHAVLDDGFIQFCADLGDVRLIGLDT
LLPGQSAGALCDKRLAFLEKALAGANGKPVVIFMHHPPFDCGIIHMDRIRLLEGADGFRE
IVARYPNVERILCGHHHRPITTRFAGTIAQIAPSVTHQVTLDLAPEGPATFHMEPPAYYL
HSYRAGTGLVSHMAYVERYPGPYPFVLDADYPGAHA
>A0A6J1XXJ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinonyx jubatus|TrEMBL
MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRNVQLPPLAFRQLEQAD
LKSESENIPRPTSLPLKILPLIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQAN
FVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFA
ALTNLQDRAPSKRSPMCNQPSINKATITGQDCQELPQNHESTKNQDPEIVIVLTLLITDY
KYVHDFEKVALSFWALSVKYGCSLNYFLKMVLVVNCFPQLSQHTEASICATEKDLKYYST
VVSYIHCDIFIF
>A0A2D4LE56|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micrurus spixii|TrEMBL
STLPCPSSRNRKRFCFLKSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESF
LYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAP
SKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRM
LNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKLPMSQISGVKKLM
HSSSLTNSSIPKFGVKTDQEDILAKELEDVNK
>A0A516IHU2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Wien|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYVVDDFATRLLFID
SSHAGTSKGWLTDETIGWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLE
LVERFPSLTRIFCGHNHSLTITQYLQALISTIPGTVHQVPYCHEDTRSYYDLSPASCLMH
RQVGEQWVSYQHSLAHHAGPWLYDENISCPTEER
>A0A5N4B1V6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photinus pyralis|TrEMBL
MIICTDENGKDNMESLDEQDGKEESNHSVLHRKSSLPLTPEDEPFDVYRSPPEIKYGLLI
PPNHSPLKLLVVCAHPDPVSEALSKAADKLGYDVTTCHSYEEALEEFLSKLHDLIVIDAR
YTSKALDYDTLCRSIRNTRGSQHTAAVALVKRSVFDKDDVTIMSLLDAGFNRCIAETTNI
VHFVNELIQIRHGDIRPLAQTAVNQSLYIALEKCSDIVLITDDSYRLQYVNRSSERFLGY
RYDELLGKSIHEQFIADPLQVTSMTSSLMRAREWQGSLLVRKKSQDTVSCNCKGIPIICA
GRVPTHFVLILDVHGITELTPTSYSLDKPRGSVQSNRRTSMDVRSVSSDYFRRTSLAKLS
ALPLEAPITKVISLLSQAQEQTNPNVVSIIDKVIEILNNTELYSPHLKDDLRLKCDEPVT
SDLITALLMQQPQIQLAPSSRRSSNDSTAVRNVSRGISKVPAQIKDLLDTSLTWEFDIFR
LEELTNKKPLIHLGMNLFLHFDVPATLNCDEKTLQNWLTVIEMNYHVDNFYHNSTHAADV
MQATAGFLEKDRLKAIMDPLDEASSLIAACSHDVDHPGKSSAFLSNCDNPLAILYNDVTV
LENHHAALTFKLTLGDDRINIFKHLDRETYKVARHNVIDMILATEMTKHFEHLAKFVNVF
CQKTSRVDGESSDYIPITLPDNITLVKRMMIKCADVSNPTRPLRLCVEWARRIAEEYFAQ
TDEEKSKGLPVVMPMFDRITCSIPKSQIGFVDYIVHDMFEAWDAFIDMPELVTYMRQNYI
RWKEFDEEGHNTSSDIRKLQNTILMAPAIIPKSSIKRND
>A0A8E2TEX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella boydii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPGRHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A2T0BGP7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clostridium vincentii|TrEMBL
MALYAISDLHLGFNEDKPMDIFGEKWNGHPEKIKNNWMKKVNEEDTVLIAGDISWAMNSD
SSSIDLQWVEDLPGKKILSRGNHDYWWSSITKLNALFENTKFLQNNYYSYKEYAICGTRG
WTCPGGDKFTEKDKKIYLRELIRLRLSLDEAKKNGFSKFIVMLHYPPTNDRFEESDFVKI
IKEYGVEKVIYGHLHGPSLKRVLNGKVDGVEYIMTSADFLDFDPTIIIE
>U1H4H0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gallibacterium anatis 12656/12|TrEMBL
MSDLFRDESAGVIKLLQVTDPHLFADEDGELLGINTFDSFRQVLSEIKKSGFESNYILAT
GDFVQDNSEAGYHRFVKEIVQLGKKIFWIPGNHDFQPKMEAVFDLYKAVIQPEKHLLLGE
SWQVILLDSQLYGVPHGMLSEEELKWLEQRLSLYPNRNTLIVLHHHLLPTNSAWLDQHNL
RNPYDFSEILAKHKNIKAIVYGHIHQEVNAVWQGIPVFATPSTCIQFKPDCAYFTLDNLQ
PGWREISLYPDGRLETKVHRIKDKVFLPKDNMNGY
>A0A550G6N6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. ALS1131|TrEMBL
MPSLPTPPSDSSVLLVQLSDSHLFADADGKLLGMDTCDSLQRVIQQVLEEQPQIDLILAT
GDLSQDGSEASYQRFRQLTAAFGTPSRWLAGNHDETPPMQAACKGSELLEPVIDVGAWRI
VMLDSSIPGAVPGFLADDQLELLERTLNEAPQRHHLVCLHHHPVPIGCKWMEPIGLRNAD
ALFAILDRHPQARAVLWGHVHQEFDQMRGNLRLLASPSTCVQFAPGSEDFQVGNEAPGYR
WLRLHADGGLDTGVSRVNGIHFEVDYSVKGY
>H2M1L5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oryzias latipes|TrEMBL
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQNDVEIPSPTS
KAREKKKQQKQQLMTQISGVKKVSHGPLLSSSSISRFGVKTDKEELLSKELEELNKWGLN
IFTVSEYSNNRPLTCIMYAIFQERDLLKTFKIPADTFVAYMMTLEDHYHSDVAYHNSLHA
ADVAQSTHILLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYND
ESVLENHHLAVGFKLLQEDNCDIFQNLTKKQRQSLRKMVIDMVLATDMSKHMSLLADLKT
MVETKKVTSSGVLLLDNYTDRIQVWCTSTPQIDRNCLWGSCDAEAEWSAYDWKIEGSVPP
FLPMCQSGGYRLAPVFSCGVATSV
>Q32BT8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella dysenteriae serotype 1 (strain Sd197)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A8B7LUC7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila elegans|TrEMBL
MESFVVDSFAASVAQSQLQSQSPPQSTSLQHSESQCTGTSGTSSSGGGNSRPGHRKSSLA
LALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLVFHKSDSICEAITAACQRHQLDVT
LVKSKEEALDTLQKSYATAQCYHLIIIDARSTKNLDAEHIARTIRHTHGHHLTTIIAVCK
KSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALH
RLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSDLSTISEQCKNIKEFD
GILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSL
HSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKV
LEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTATI
VPAKMKSNPIIMELLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENV
CKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDMLVMDRMEEATALIAAAA
HDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYK
SARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPREHNSQTDEETSILMRRMLIKVADVS
NPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQD
MMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLAEIMAKQPPVGKMANSK
>A0A2Z3X200|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. CRE-46|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEFDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSSLQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVCRLQGNRFHPDTASEGY
>A0A8B7LW97|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila elegans|TrEMBL
MSSSVSPGSTGTSGTSSSGGGNSRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLP
PNPPLKALLVFHKSDSICEAITAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIII
DARSTKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTN
LAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLN
MRLDEIISKQLEDIFVSDLSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGS
APTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLT
SLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDL
IGALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKSNPIIMELLDESLSWDFDIFK
LEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADV
MQATGAFITQLTNKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDL
TVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVS
VFGGEEPREHNSQTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEE
KQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKK
YDEQGVNTLAEIMAKQPPVGKMANSK
>A0A5B0EXR1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. ANT_J28|TrEMBL
MPSVSILTTADSALLVQLSDSHLFAETDGTLLGMNTRDSLQKVIELVRLQQPQIDLIIAS
GDLSQDGTLESYQQFRDLTRQLDAPARWIPGNHDEPRIMAEAAVQSALLEPVMDVGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPD
ALFAVLDRFPQVRAVLWGHVHQEIDQIRNGVRLIASPSTCIQFEPGSDDFKVSDQAPGYR
WLRLLPDGQLETGVERVTGFDFHVDYGSNGY
>A0A5J4Q7C4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
VLVQVIGNILPLSLATIMYRVGTSWFFIFIYLLIIFLLLELVRVTGLCPVAKFMHGSWYG
LGVLAGALTLILTWGYIVYLNKARVELSLTVNKEVGTERSLKIVAISDLHLGYGIGREEF
EGWIKLINKENPDIVLIAGDAIDNSVRPLYERGIAESFKQINTKYGIYVSPGNHEYITGI
SSSLAFLKEAGITVLRDSVAFINDTFYIVGRDDRANNARKSLEELTDTLDKSKLLILLDH
QPYNLEQAERNGIDLQISGHTHYGQIFPISLITEMMYEKAHGYLKKGDSHIYVSSGLGLW
GGKFRVGTRSEYVVIHLTPLKTL
>A0A6N4X859|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chryseobacterium potabilaquae|TrEMBL
MQRNFLIITAIFLFLEVYIYQAIRTLTDSLWVKLGYWIITLTIYGVFAYEMTHYQRSDRS
TVRAQIMISLFLIFILPKVFIVLFLLIDDIFRGWSYLIGLTRPTENFFPERRKFLSLVGL
GLGGVLSALFIDGITFGKYRHKVRKVKVKLPNLPKSFKGYKIIQISDVHSGSFSDPSKLE
HAIELINEQKPDLVLFTGDMVNNVADEFKPFIPLFSKIKAKDGKLAVLGNHDYGDYVTWG
SLEEKKKNLETLIDYEKQAGFDMLRNENRIIEKNGDKLYILGVENWGLKPFPQFGKIDEA
LKNVPNSATKILMSHDPTHFDYVVKKHTGNIHLTLSGHTHGMQFGLDLKNVKWSPVQYRY
PKWADLYESEGKLLYVNRGFGVLGYPGRVGVLPEITLFELG
>B5F676|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella agona (strain SL483)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5N7XVY8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp|TrEMBL
MPSLPTPSADSSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIQQVQEEQPQIDLILAT
GDLSQDGSEASYRRFRQLTTTIGAPTRWLAGNHDETPPMQAVCKGSELLEPVIDLGAWRI
VMLDSSIPGAVPGFLAENQLELLEHTLGEAPQRHHLICLHHHPVPIGCKWMDPIGLRNAD
ALFAILDRHPQARAVLWGHVHQEFDQMRGNLRLIASPSTCVQFAPGSEDFQVGSEAPGYR
WLRLHADGTLDTGVSRVTGIDFEVDYSVKGY
>A0A5C9STN7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cholerae|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFAAEDGCLLSVNTADSFAAVVAAIGGEQIEFDAILATG
DISQDHTPESYQRFVRGIQPLQKACYWLPGNHDYKPSMHSVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEYPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRLHLGARVMASPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A1E5B7U5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus ZS-139|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVNQGFDYEAILA
TGDISQDHSAESYQKFESGIQPLERPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEKKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTEVRRLPRGQFLPDFTAGGY
>A0A2H5W1X6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR10|TrEMBL
MRILRWRWRERAYRREREGFFHALRHLSRREFLRVMGEVGAWAAAQGAWWHTFQLVDIVV
GKRRPRFRLAYITDTHLFRPQMNERFLRAALRAVEDLNRLDPPPDFVVMGGDLAHGGERA
ELELGREILKQVKAPVKMVVGEHDWYLDLGEAWQQMFGSPNYSFDHRGVHFVVLMSVRMR
DFWTERRMTPHERMRAVGQLDHPETSRFEVGEHGRQWLAEDLAKVPREQPVVVLTHAPLY
KYYRRWNFWIEDAEQVQALLAPYRAVTVLHGHTHQVVTHRIGTIHFHGMLATAWPWPYAP
EGLPPLTVQMDRVDPFDELDGVGIGALDLYADGYGDKQYFFFRREPLRIARAYLQSWGRE
AIPPAPEFPWY
>A0A8B9GB20|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Amazona collaria|TrEMBL
IYMGSNFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKT
MSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNR
>A0A849UB20|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylococcaceae bacterium|TrEMBL
MNADLKNLTILQLSDLHILSEPKATFLGVDTMHYFQECLKLAFSMGRHFDLMLLTGDLAQ
EPVYQTYQRILSSLKDYSDVPCICLPGNHDDFGLMQQAFVNDAVNCRKQITLGRWQIINL
NSQIPGKPAGRLAESELSFLEQCLENFPQQYAFIAVHHHCVKTNSSWMDTMMIENSDELF
AHLARFPQVKLITSGHIHQVLDINLGQIRVLGTPSTCFQFEPGCDKFSVVDTAPGFRLFQ
LGRDGGISTEIVRLPVNLAGVVNANQIY
>A0A811T001|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella hafniensis|TrEMBL
MLKEAVSYSIAEGESVRIVQVTDPHLFADPEAQLLGVNTSKSFAAVLNTIRAVDYPAHIM
LATGDLSQDYSAESYQQFVRAVTPVGLPCHYLPGNHDDPRIMYLHMQGEQIFGQQRILAG
KWQILMLDSTVRGKPGGHMAQSQFELIEQAIAAHPECYTLLVMHHNPILVNCTWLDQHCM
DNGAEFLERVAMYPQVKGLLWGHVHQRIDTHYEGPHGALQLMATPSTCIQFKPLSPYFAL
DGLQPGYRLLELKADGSIGTNVYRVPGNHFFPDNDSSGY
>A0A7Y3INK9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio plantisponsor|TrEMBL
MNVSPSIDNPDSIKLVQITDTHLFAPDDGCLLSVNTADSFRAVVKEICTQKVQYDAVLAT
GDISQDHSAESYQRFSESIKMLEKDCFWLPGNHDYKPNMGAVLPSPQIRTEEHVLLGEHW
QMVLLDSQVVGVPHGRLSDHQLALLDEKLTQYPDRYTLVLLHHHPLLVGSAWLDQHTLKD
SESFWDVVKRHSNVKAVLCGHVHQNMDKEHMGVRVMATPSTCIQFKPNSNDFALDKTSPG
WRELELCADGTVKSAVKRLANGVFQPDFDASGY
>A0A5C8ZX83|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Parahaliea aestuarii|TrEMBL
MTHFLAQRQDLPHDGGTVRICQFTDCHLAGERGGRLLGMDTDHSMLAVIEQARRDGRRAD
LVVATGDLADGGAPAAYLRLQAALQAFCPRQFWLPGNHDDCAAMAAVPGSEELLCGDLRI
GNWQILLLNSQIPGEIGGEIGADQLGALQRALQSAADDRLHTLVCLHHQPVPIGCDWLDE
QRVADADALFAVVERFPGVKALLWGHVHQEVDRRRGDLRLLSSPSTCVQFAPGSEDFQAD
DQPPGYRWLELHEDGRLDTGVSRVQGVTFEVNLQQRGYLKH
>A0A1Y6MPM6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium andalusiense|TrEMBL
MQTYSLPQSNPDSVVLLQITDTHLFANGSGSLLGVATKDSFHAVLNGVDTAARHFDAIVA
TGDISQDHTPYSYQRFADGISRWSQPCFWLPGNHDFQPTMQSILPSEQIKPHQQVLVGEH
WQMILLDSQVQGVPHGEVSAAQLALLEAALARYPDRYALILLHHHPLEAGSAWLDQHQLH
NNHQLWNVIDKFPQVKAVLCGHIHQNLDRIYHGVRVLATPSTCIQFMPDSDDFALDDNNP
GWRYLELTRDGQIITSVHRIDGDQFKPKLDAEGY
>A0A385ZN24|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces griseorubiginosus|TrEMBL
MRILQLSDTHVERADAPNRNGVNATESLRLMLAELRHLRDVDAVVVTGDIADAGEVEAYT
AVRELVGEFARPRNAPVFYTTGNHDEREAFGKVLGSGHAEPECVLETDAAERAAVSTVGG
HRFVTLDSLVPGKVYGRISPAQLDWLREVLSTPAERGTVLAFHHPPISLALSVTQQVFGL
LDPGELAAAIRGSDVRVILTGHYHLQLFGMLESLPVWVTPGVVNRIDLTTPYGTERAVRG
ASASLVELGGPASPMFHTFHARDPRAHETVYQLDEERTRAVVAEHGP
>A0A564TAY4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Faecalibacterium prausnitzii|TrEMBL
MNTQPVTFAAMTDLHLDIMHDGMMRIDAFLDAAQKADVDFIIQLGDFSYPKDTSTCLCAP
EKMPINLKYAMECPTEIPKLEILNKFNLFSKPKYHLLGNHECDFCSKADALEMYGMEKPY
YSFHLKGWHFIVLDGNSYRDEHGDLVDYNFGKYFETTDLPYLGEQQLVWLREEVLSATEP
IVIFSHQPLYACPRGLRNVDDLQKIIREGRAAGKRIQFCMNGHVHRDIRHFENGILYYTL
NSISNYWAGTAYATHRYSSEIEAKFPNLQFVVPYADPVYAIVTLDENGISLKGVEGHFVP
PSPEKTGITVPLTPSVASWSFAWDEFETLHGDV
>A0A385ZGW2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces griseorubiginosus|TrEMBL
MGSAGNFTAMDLPDFGIPPQLARRMSMAEQHEYLRTKLTRRRTLVTAGAVAGGLLTGCSA
EGKATRGTAAAGRATPSVHGSAITPFGRHLAFGADPRTQMRVSWQVPLAVRKPYVRIGLR
PDDLSRKIEAELRDLHTPGQSGVRLALDQYYLHAALDGLRPGTTYYYGVGHEGFDPADAG
HRATLSSFRTAPTSPESFVFTAFGDQGVGTAAAANDNLLLRRKPAFHLHAGDLCYADANG
QGLTSDGYDPGFWDLFLKQNEGVARSVPWMVTTGNHDMEAWYSPDGYGGQLARWTLPDSG
FDPRSAPGVYSFAYGNVGFVALDANDVSYEIQANLGHTDGKQTAWLDRRLGELRAAKGID
FVVVFFHHCAYSTSSHASDGGVRALWLPLFEKHQVDLVINGHNHVYERTDAIRGGEVGRR
VPVGGATDPTRDGIVHVTAGGGGRDLYGFPPGVQESYEGRVHDHESVETFHWTRSRQAHK
ETVEWSRVRYRGFSLLSVEAHSGARPSLTVSALAQDGKRVDHFEVRRGA
>E0WS81|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Regiella insecticola LSR1|TrEMBL
MKKGAYLENLFKLPVPANETEIRILQLTDTHLFADKKKTLLGINTADSYSAVLEAIATQK
QRFDLIITTGDLAQEPAITSYQYFARGMAELLPTPCVWLPGNHDNQKIMADVLFDEGITA
TKQVTISDNWQILLLDSQVSEQPYGHLSDHQLLWMEQCLQMFPQHYTLVALHHPPLACGC
RWLDQNNLRNASMLAEIVLRYPRVTTLLCGHIHQEIDLNWCGKRLLATPSTCIQFKPDHA
TFTLDNAAPGWRCINLQPDGTVKTQVKRLANGLFYPDINANGY
>A0A3S4KLA4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella aerogenes|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A1A8JJS1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothobranchius kuhntae|TrEMBL
MLKRSWSAQGGTPSDENPDPLVGQFSSGCTLGVEACKVHRRFSGNLQLPPLSWRQAETER
DRGRPLTPEEDPVTRSRPTSLPIVSLPRIDITQADSDSLEVENAPPLCCSPSDLQASPGS
GLVLHPNMANHGQRRESFLYRSDSDYELSPKSLSRNSSIVGELHSEDLIVTPFAQVLASL
RTVRNNFTTLTNVQCASTKRSPAANQPCVTKVCLSDESYQKLAMETMEELDWCLDQLETI
QTYRSVSEMASNKFKRILNRELSHLSEMSRSGNQVSEYISNTFLDKQNDLELPCPVQKSR
ERKRRQGPQQQQQQHQVGMMTQI
>A0A2J8LTA9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pan troglodytes|TrEMBL
MQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVR
SNVAALARQQCLGAAKQGPVGN
>A0A2J8LTB9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pan troglodytes|TrEMBL
MQGPPAPAPVPGPGSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENGLSCGR
RALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIV
TPFAQVLASLRTVRSNVAALARQQCLGAAKGHGAEAGIGDARRAGLVPGSVGDAADPALG
GGDGLQQVQADPEPGVDPPVRNQPLREPGVRVHLPDLPGPADRGGAAQGDR
>A0A482UJJ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas songnenensis|TrEMBL
MPGATLTAVEDSVLLVQLTDSHLFAEADGKLLGMNTCDSLERVIELAIDEQPRIDLVLAT
GDLSQDGSVASYQRFRRLAERIEAPARWCPGNHDELASMREASRGSALLEPVLEIGGWRV
VMLDTLVAGSVYGMLRSDQLDLLDQALTEAPAHHHLICLHHHPVSIGSRWMDSIGLRNPD
ALFEVLDRHSNVRALLWGHIHQEFDHWRNDLRLLASPSTGVQFTPRSEDFQVDSVAPGYR
WLRLYADGRLNTGVSRVSGIEFEIDYSVKGY
>A0A365PTB4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas zhaodongensis|TrEMBL
MAAAPLTVENDSVLLVQLTDSHLFAESGGKLLGMDTAESLQRVVDLVLEEQPRIDLVLAT
GDLSQDGSLASYKRFRQLSERIDAPVRWCPGNHDELTSMQEAVRGSEMMMPVLDIGAWRV
VMLDTLVPGAVFGMLREDQLDLLERTLQQSPERPHLVCLHHHPVSIGSRWMDSIGLHNSE
ALFDVLDRFSCVKALLWGHIHQAFDSERRGVRLLATPSTGVQFTPGSEDFQVDTLAPGYR
WLRLYADGKLETGVSRVVGTDFIVDYSVKGY
>A0A2H9TB44|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|invertebrate metagenome|TrEMBL
MKRNVLCAVVIISILAASSMLFHKKHSPPEKKPSVNEPGRPLPDESHTFSPFVPQQQPDR
ICLTLTHDPTTSINIQWRTHNLSGHPVVQIALLSAGPIEKTGIIQTCLASSQIFRHPHYD
AVHHHANITGLKPATTYLYRVGDGLKWSEWFQFQTSQPSHQPFEFLFFGDLQEDIRGSCS
RIIRQAFLNHPNTRFMLFIGDIVRHGNNDTEWHEFFQATGWLTGMFPTIATPGNHEYKNT
QITSAWGAHFQFPSNGPQGCEELNNTCYFIDYQGTRFISLNTNAMRGFHLKAVLAQRQWL
QTLLRNNDNDWTVIFHHHPVDSPTQSESGKKQLQWLFSPLYEKYHVDLVLQGDAHTYGRG
HKSHDKNNPDSPIYIVSNSGAHMNKPDAPWASVSGSDKQLYQHISISKNQLNYQAIAADG
SLFDHFILKK
>A0A421DT48|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Brenneria alni|TrEMBL
MESLLTLPVASGARIRILQITDTHLFAGEHETLLGINTYRSFHAVLDAIQAQQYAFDLIV
ATGDLAQDHSLEAYRHFSRGIRQLDAPCVWLPGNHDFQPAMVDALAEAEVAPSKHVLLGD
NWQIILLDSQVFGVPHGELSDYQLEWLERSLQSQPERFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLAAVLARYPRVNTILCGHIHQELDLGWHGRRLLATPSTCVQFKPHCTNFTIDNVA
PGWRYLDLMPDGQLETEVFRLSGSEFLPDMDSDGY
>U4S996|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Glaesserella parasuis D74|TrEMBL
MDDSYIFPLSSPIIRILQITDSHLFASDTCELLGVNTTQSFQAVLNMIMKESFEYDLILA
TGDLVQDHNREAYHRFAKMVKPLVKPLFWVAGNHDLQPQMRNALSIYSQIKPEKHILVGD
HWQIILLDSHIQDSPKGRLEFSELAFLKRKLEVHPERYSLIVLHHNILPTNSAWLDQHSL
SNVNDLLATLKAFPKVKAIVHGHIHQEVDAQWNGYRILSTPSTCIQFKPHCNDFTLDAIP
QGWRELCLNIDGFIDTVVKRLDNNNFLPNFKALGY
>A0A067RHJ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Zootermopsis nevadensis|TrEMBL
VFQVLLAFGSDDLQGDAICSACEELGYEFSLASTRETVLEAFQATNHEIVVIDTRNPKII
DGESICKALRSLKTAQYTVIVGVVRRSTTEKEDSSVAPLLSMGFNRVFTETYSLVQSVNE
LLQLYVSDVQPRLQLSSAQAAYVALDKCSDVVHITDQNLNIQYMNRSSERFLGFSMEDVA
GKSLLEANSVDNRDLMVQQLQRGREWEGVISWRRKTGDCVVLSGRVIPVYITGRSPTHYV
FIHESQSVALDKRISGTLVKNPELPKGTNNRKGSADLKSISSDGLRRQSIAKLHNLSIEA
PITKVIALITSVQENASLEDIQTLDKVIDILRTTELYSPQLKDDKGKPGDPVTNDLIGAL
LSSGPAVTPFARRSSSDSGSVSRIGLSRSTFKPVNMSHQMKELLDTSLLWDFDIFKLEEL
SSKRPLVYLGMNLMNHFDVSSSLGCDENVLHNWLVIIEMNYNSKNSYHTSTHAADVMQAT
AGFLERERLKQILDPLDEAVCLVAAAAHDVDHPGKSSAFLCNSNHELAILYNDLCVLESH
HSALAFKLTMSDDRVNIFKCLERDVYKAVRQNVIDMILATEMTRHFEHLAKFVNVFSIKK
EDDSPDGGRSSPDIGVLTAPENITLIKRMLIKCADVSNPTRPVRMCVEWAVRIAEEYFNQ
TDEEKENHLPVVMPLFDRATCSIPKSQIGFMDFIINDMFETWEAFIEMPELLQNMQHNYK
FWKEKEKFGIHRIQDVITMQRTWKD
>A0A221FUU2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia marcescens|TrEMBL
MESLFKLPVASGAAVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAIQAQHRDVDLIV
ATGDLAQDHSQEAYRHFAAGIAQLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLLGD
NWQVLMLDSQVFGVPHGELSEYQLEWMERCLQAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAILLRYPKVNTVVCGHIHQDLDLEWQGRRLLATPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A1Q4NVP4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia marcescens|TrEMBL
MESLFKLPVASGAAVRILQITDTHLFAGEQETLLGINTYRSYHAVLDAIQAQRRDVDLIV
ATGDLAQDHSQEAYRHFAAGIAQLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLLGE
NWQVLMLDSQVFGVPHGELSEYQLEWMERCLQAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAILLRYPKVNTVVCGHIHQDLDLEWQGRRLLATPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A8F9N122|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O141:H4|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A803VXN6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ficedula albicollis|TrEMBL
VARGSPPGFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSP
KTMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNK
>A0A5A5R903|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcystis aeruginosa NIES-2519|TrEMBL
MNFRFAILSDPHIALPTTILNHSNRFHLVEVSIPALKIVLDHLITLNLDFLLIAGDLTQD
GEPENHRWLADCLATLPFPVYVVPGNHDVLSLTATENQIGLGDFPFYYQQFGYSHPEQIY
YQKEILPGVQLIGLNSNQFDEQGGQIGSLDAEQLHWLKQTLPSLKNDLVMVMIHHNVIEH
LPGQSNHELGKRYMLANAGELLDILEENGVKLLITGHLHVQDLAFARGIYEITTGSLVSY
PHPYRVLEYCENTGELAIESFHLQNIPGWENLPAISRQWLGDRSYPFMMRLLTCHPLNLP
MSLAEELAPKLRNFWADVAQGDTIFDFSDFPPLVRRYFYAFSAIDSLGNPHFIDNQAVIS
FKHQFSYQRSNLLVEMRE
>A0A0C5WY80|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium gaetbulicola Gung47|TrEMBL
MQNFTLPQTNRDSVVLLQITDTHLFADDGGSLLGVTTKDSFHAVLDAVDAAARPFDAIVA
TGDISQDHTEYSYQRFCEGIARWSQPCFWLPGNHDYQPSMQAVLPSPQIKPCHQVLAGEH
WQVILLDSQVKGVPHGELSGEQLDMLDQALSAHPNRHALVLLHHHPLPAGSAWLDQHQLH
NSEPFWQVVGRYPQVKAILCGHIHQELDRIHRGVRVLATPSTCIQFQPDSQDFALDQKSP
GWRYLALHRDGQLDTQVHRLDGHDFTPNFDSAGY
>A0A5A5RMP2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcystis aeruginosa NIES-2520|TrEMBL
MNFRFAILSDPHIALPTTILNHSNRFHLVEVSIPALKIVLDHLITLNLDFLLIAGDLTQD
GEPENHRWLADCLATLPFPVYVVPGNHDVLSLTATENQIGLADFPFYYQQFGYSHPEQIY
YQKEILPGVQLIGLNSNQFDEQGKQIGSLDAEQLHWLKQTLPALKNNLVMVMIHHNVIEH
LPGQSNHELGKRYMLANAVELLDILQENGVKLLITGHLHVQDLAFTRGIYEITTGSLVSY
PHPYRVLEYCENTGELAIESFHLQNIPGWENLPAISRQWLGDRSYPFMMRLLTCHPLNLP
VSLAEELAPKLRNFWADVAKGDTIFDFSDFPPLARRYFYAFSAIDPLGNPHFIDNQAVIS
FKHQFSYRRSNLLVEMRE
>A0A7H8Y3B3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mannheimia varigena|TrEMBL
MRECLKIDKRGVIRLLQITDPHLFSNPEDKLLGVDTLASFKEVIQQIKKQIIRAGDSFDL
ILATGDLIQDHQIQGYEHFAKITKALNLPIFWLEGNHDSPTEMNEILSAYSHVMPHKHIL
VGEHWQILMLNTHVTGQAYGELTESQLNWLESKLAEYPEHFSLIVQHHNILPTNSAWLDQ
HSLKNAKELEKVLSKFDKVRAIIHGHIHQQVDAHWQGIPIFATPSTCIQFKPNCDEFTLD
ILPQGWREFYLYENGELETVVKRLNSNEFLPNLEAKGY
>B1KHX0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella woodyi (strain ATCC 51908 / MS32)|TrEMBL
MLEEAISYSIDVEASVKIVQVTDPHLFADHDAQLLGVNTAQSLRAVLNTIDAVHYPADFM
LASGDISQDYSAESYHNFVKAISPLGLPCHYLPGNHDDPRIMRLNMQGPKIFGHRRILVG
SWQVIMLDSTVRGKPGGYMSDAEFELIKAAAEDQPDRHILLAMHHNPILVGCAWLDQHWM
SNGSEFLELVAKIPQVKGLLWGHVHQQIDQEYSGHHGPIKLMATPSTCIQFKPKSSYFAL
DAVQPGYRLLELKADGNILTNVYRVPGELFSPDKSASGY
>A0A8C8JA66|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oncorhynchus tshawytscha|TrEMBL
MKEHCSPLHASPPGHPGTPIRHGHPALGPPPCSVLDMEPLGPEFVSAVCLLTDESYQKLA
METMEELDWCLDQLETIQTYRSVSDMASNKCRTALQTPTERRLYGDQRIQLGRPTSEFTG
LQTVALQWSCSQQVGGLP
>U9XV98|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli 113303|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>O77824|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Felis catus|TrEMBL
PWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKDREKQP
APRQRPSQQPPPPGPQFQPMSQITGVKKLMHSSSLSDSSIPRFGVKTNQEELLAQEL
>A0A550E6M9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas mendocina|TrEMBL
MPSLPAPSTESSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIERVQQEQPQIDLILAT
GDLSQDGSVASYQRFRQLTSAIAAPARWLAGNHDETPPMQAACKDSELLEPVIDLGAWRI
TLLDSSIPGAVPGFLADSQLELLERALSEAPQRHHLICLHHHPVSIGCKWMEPIGLRNAD
TLFAILDRYPQARAVLWGHIHQEFDQIRDNLRLLASPSTCVQFAPGSEEFQVGNDAPGYR
WLRLHADGKLDTGVSRVTGIDFEVDYSVKGY
>A0A6I1Z193|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces sp. RB17|TrEMBL
MKILHLSDTHLDRAGRPDADGADGTTALRRILADLIHLRDLSAVVVTGDVTDDGSREGYA
RARALLDAYARERGASVFYATGNHDERAAFTEVLGCGHAHPDAVCAGPDGERAAASTVDG
WRLVTLDSLVPGKAYGRISRAQLDWLRRVLATPAPRGTILAFHHPPVALEVEVQQALGLQ
NADKLAEVIRGTDVQLILCGHFHLQIVGRLEQATVWVTPGVVSRIDLTARPGTERAVHGA
SASLVQLGTANGPLIHTLHARDPRVGETVYEADEDEMREIIEELGPSRMSPS
>A0A558I4R8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio tasmaniensis|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVNQGFDYEAILA
TGDISQDHSAESYQKFESGIQPLERPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEKKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTEVRRLPHGQFLPDFTAGGY
>A0A8I1VQ35|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio parahaemolyticus|TrEMBL
MQSSNDSIKLLQITDTHLFAADEGSLLSVKTADSFSAVVNEVLRRKVGFDYILATGDISQ
DHSAESYQRFADGIAPLQKDCYWLPGNHDYKPNMGSVLPSPQIQAAEHVLLGEKWQLILL
DSQVVGVPHGRLSDQQLTLLEEKLTEFPERHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFDNVKGILCGHVHQDINVIHKGIRVMATPSTCVQFKPNSDDFALDTTSPGWRELE
LHTNGDITTHVDRLPEGQFQPDFSSNGY
>A0A1X1EYI1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea cypripedii|TrEMBL
MDSLLTLPAASGADIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIEAQQRDYDLII
ATGDLAQDHSVEAYQHFVTGIARLPKPCVWLPGNHDFQPAMVNTLAEAGIAADKHVLLGE
HWQLVLLDSQVFGVPHGMLSEYQLEWLEKTLAKFPERHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLQNFPRARNLVCGHIHQELDLDWHGRRVLATPSTCVQFKPHCTNFTIDTVA
PGWRWFTLKPDGLLQTEVDRLQTDAFRPDLDSEGY
>A0A837G1Z2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio coralliilyticus|TrEMBL
MKVTSCSSDGSIRLLQITDTHLFEATDGSLLSVNTADSFNAVVDAIVEENPVYDAVLATG
DISQDHSEVSYQRFEQGIVPLKKKCFWLPGNHDFKPSMNSVIPSQQIQQIDHVLLGDTWQ
MIMLDSQVVGVPHGRLSDKQLNLLEEKLSQYPERYTLILLHHHPLLVGSAWLDQHSLKDS
DDFWQVVDQHNNVKAVLCGHVHQDMNVMRNDVRVMATPSTCVQFKPNSDDFALDYQSPGW
RELLLRDNGEIETQVKRLPAGCFQPDFNSAGY
>S5N0A5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella bongori N268-08|TrEMBL
MRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIRAQQYEYDLIVATGDLAQDQSAAAY
QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVLIGEQWQILLLDSQVFGV
PHGELSEFQLEWLERKLTDAPERQTLLLLHHHPLPAGCSWLDQHSLRNAAELDSVLANFP
RVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIAPGWRTLELHANGLL
ETEVHRLQDTRFRPDTASEGY
>A0A812GEY9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. B1ASS3|TrEMBL
MQSSSDSIKLLQITDTHLFDADEGSLLSVRTADSFAAVIQEVLHRQVQFEYVLATGDISQ
DHSAESYQRFAEGIAPLKKDCFWLPGNHDYKPNMGSVLPSPQIQAVEHLMLGEHWQLILL
DSQVVGVPHGRLSDQQLSLLEEKLAENPQRHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFENVKGILCGHVHQDMNVLYNGIRVMATPSTCVQFKPNSDDFALDTESPGWRELE
LHSNGDITTEVNRLPDGQFQPDFTSNGY
>A0A8C5W3U1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcebus murinus|TrEMBL
AFHFDVDNGTSVGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRN
SSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATIT
GKKDLGSYSSHLGRNCIFQESI
>I6CGJ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella flexneri K-315|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A5C0WJ80|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacillus safensis|TrEMBL
MVNVSRQIMLLCFFIILFCFSQPASAGPFLQTEVNVPDKPFSPFIFDQFHVDVRPVLGKS
HDLQFRASISDQEQILSANLYYKQSDELGYRLIPMERLPGMKPEFTAKIPPDQLWNPTVR
YYTEFLTQKSVIKTAEKSVHLNGFEEDLSHIPDLFITEIVVNSKNRKGKDAFEFIEVYNT
THAPISLKHYQLRYRNPAQGIEMDDVYSFHTNSVTISPGKPYVFWLRKKGQEHLTTADFN
AMYKSQLKEGEHLSIIESKGLSNSKSRLVSITTNIGEEISSAAFRLKPSWFSEHKSLLFK
YPMDGTTQTKLISKIEEEPTPGKVLKAQIPSEKKEISQDIHKPVIEDMTVRKPVKPTESV
EIKADVQDDQAVKTVKLRYRTNRKDPFKEILLQKDHNDRLFHHIIYSPELIGKEQLEYQL
EASDGENEAKTLKKTIDVEQVSKAHGLRFNVEEGDTVSGLFSLKATSDQKKSIELRIDGK
RNQQVSSALEADPYIAFDVKGTNLYFKNGVSIGRRLLSIFDDSTKVYRTYTMPIPEEEIK
KAGLQTISFHAGTKSSPVDRLPGENHDDFELKNVRMILSNGTQIPPINAKPLKEWRMGDS
GNAKKVRTFQFEIPKEAYVSTYIKWDTKRLKEGPHLIEAKTSDEHASVRVKVDNTGPRIK
TNVQAKDQYKGAFTLKAKVTDRWSDIEELKAYVDGKPVSLPYQTSSSELKPGKHTFTIKA
KDAAGNMSTLKKEFKTVHEHPETPERVADKTKMKSSKQTVLTKDPTNDKLDYSFYRAYQY
TSLHPSMKIFKYAAETEPPKSYLQKGEMIFSDQERNRIAFVDGKSVETKDLQRFPYHRFQ
IKVHHGVREKDVVEAVWKGSSLSGRKVTMYAWNHQQEKWDKITHHFAKDQKEFYLKGLLS
VRQYMKNQTFDLLVQDEISKSQKPYKMVWMSDTQYYAKSYPHIFKQMVEWIRDQREKLNI
QYVFHTGDIVDDSKDKQWHRADTFMRVLDQNHIPYGVLAGNHDVRHKDGLYAEYGKYFGE
KRFADKPYYGESYRNNKGHYDLISAGGNDYMMVYMGWGIKQDEIDWLNRVISEHPDRIVI
LNFHEYLLVSGNRSPIGDLIFHQVVKRHPNIVAVFSGHYHGASRKVDELDDDHDGKVDRK
VYQILADYQSGPEGGQGFMRVITADQEKNQLHFTTYSPYLNQEHFYDPKTYGDQDEFSID
VDLTPKMKSVKTNYFELNVYTNVLLGEARGVKSGKKASFEWKGLKPNEDYYWYTVAKDRF
QGKAISPIWKIHTKDDDETKFLRK
>A0A2W1JXW0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acaryochloris thomasi RCC1774|TrEMBL
MSLNFRFGVISDLHIGLPQTIEDSPHRFHLVELSVSALESALTHLSQLDLDFLLIPGDLT
QDGEPDNHTWLSQRLAQLPFPSYVIPGNHDVISPIPTDTCIGLQEFPGYYPKFGYQNPEQ
LYYTCALLPGVRLIALNSNQFDLAGYQLGILDDQQLAWLQTVLEETVDELVLVMVHHNVL
EHLPDQTQNPVGKRYMLDNAPKLINLLQAHNVQLVFTGHLHVQNIAHQNGLYDVTTGSLV
SYPHPYRVIQVQQQAEQTQVEIESHRLRSLPDWPDLQTTSRQMMGQRSTRFMTHFLTQPP
LNLPVEKATTLAPQLSDFWATVADGDPVLSYPELPEPVQQYFEAFSHSGVADNQLIISLQ
T
>A0A4R3ZFQ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Raoultella sp. BIGb0138|TrEMBL
MESLLNLPLAGETRVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRQCDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEEPERYTLLLLHHHPLPSGCSWLDQHSL
RNAGALDRALTAYPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHADGTLITEVCRLEGVKFHPDIASEGY
>A8GJR9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia proteamaculans (strain 568)|TrEMBL
MESLFKPTVASGARVRILQITDTHLFAGENETLLGINTYRSYHAVLDAILAQQRDFDLVV
ATGDLAQDHSLAAYRHFAEGIARLPAPCVWLPGNHDFQPAMVDALADAGIAPSKQVLVGD
HWQVLLLDSQVFGVPYGELSDYQLEWMERCLQAYPERYTLMLLHHHPLPSGCTWLDQHSL
RNPHMLGAVLLRYPKVNTLLCGHIHQELDLEWQGRRLLASPSTCVQFKPHCTNFTIDEVS
PGWRYIDLLPDGRVETQVFRLENDDFRPDMDSEGY
>A0A679K8K3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium bullatum|TrEMBL
MPIVHRRRYESMFHLIFGLPCLYVITRVLWPLPWPLAVKAGVAVLLLVASQYHLWSRLSS
GSVFAPEFPRLLIVLFNWAFGAIVLLAAMQLALDVVALASKIMPGGGWAIPAGWRYAEAA
LAMLLSAVAVQQAVRVPPLKDVTVEIENLPAGFDGFTLLQLTDLHLSRLFPATWAREVVT
RSNALGVDLVVVTGDLIDGALASRRADVEPLRDLRAPDGVWVIPGNHEYFFDYAGWMRRY
AELGMGVLENRHTILRRGADALVLAGVTDLSASHSGRPVHDLDAALAGAPPDAPIVLLDH
QPKDAARAAAKGVALQLSGHTHGGMIRGLDRLVARANAGFVSGPYAVGAMTLYVNNGTGL
WPGFALRLGPPSELTRITLRGKPRS
>A0A6P5VLR4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila obscura|TrEMBL
MRNCLPKLTNVFRRKSSAKSSATGPGHTNHSNDCHSDSDSEQYTAVAMSGSLAIPSPQYD
PARDNNNERPHRDGDSSYSRLISGPSNLESTAVAPNVRSRAVEESSFTEMRVETISGQAA
GPARLSIPIPGRNSISLPFAGLSSSKTPEEMELEYEANVKAEVGDIVTPLRRNNTSSTRP
HSMAFNGGGRSASLQPEIVEAIRNLDVQGLFLNNLAIEEDRTDIESDQSQGHEDAVVLRR
KVAGLERKSCSLYERRMPKTPKLHLMVAGKKPQPQPQQQQQHQQQQDGGDDDEFKVFQRN
LMDLKYPTVLPPNPQLKALLVFHKSDSICEAVASACQRHQLDVTLVKSKEEALDTLHKSY
ATAQCYHLIIIDARSSKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDA
GVNRCIAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQ
YANRATERLLNMRLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMH
VRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASD
GLRRTSLAKLTSLPLEAPITKENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIAT
DLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKANPIIMELLEESLSWDFDI
FKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAA
DVMQATGAFITQLTNKDMMVMDSMEEAMALIAAAAHDIDHPGRSSAFLCNSNSALAVLYN
DLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKF
VSVFGGEEPREHNPQSDEETAILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTD
EEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQW
KKYDEQGVNTLADIMAKQPPMGKLANSK
>A0A1Q3FUP7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Culex tarsalis|TrEMBL
MWLNGLCCGGGLCGIGDVLKDHHHQQQHQHQQEEEDGPGDCGLAAALRGCPGGRCSTCTV
MGCTPSILSNSSGGGSSNGQQNRKDSGGIYGGVPASTAVATMATSVATTGHDCIKKDSIV
SITGLGPVSVVSSVLRRPTIGSGTSSSSGRHGPRQTSSLALTPEEEPLDSYPRLISDLKF
PNLWPPNPPIKILIAFCKNDPVFEALVSASHRLNFEPTFVKSHEAAIEAFQNVATGGHHI
IVVDARHPRIIEADALGRSIRNSKGSQHTTMVAVVKKSVFEKDDTAVISLLDVGFNRCII
ESPHVSICSSELRQIQHSLVRPQNVISTQQALYTALHRSREAIIITDDSLRAQYANRASE
RILNMKLDEIVGRSLSELVTADVSNILSQTSRHKDYEGFISTRRKSQETLHIHVRAVPVS
CIGRSPTHLVLILESPASGTTLTALASDALQTLPQGKEVARGSLHSIRRGSFDVRSIASD
GLRRTSLAKLSQLPLEAPITKVLSLLAQVQENCSQDESKLLDRVMEFLKREGLYSPQMKE
IRTEDPVATDLIGALLTQGPTNTISSRRSSNDSIIRGGGRPSTGSIVFTKTRESTQLNEL
LNNALAWDFEIFRLEELTERHPLVCLGLELFRRFDVYNTFNCDENTFERWLHKMEEHYCS
KNTYHNSTHAADVMQATACYLQQLSNRELKVMDRMDEATALIAAATHDIEHPGRSSAFLC
NSDDRLALLYNDICVLESHHAATTFQLTLGDDKINIFKHLDRESYKLARSVIIDMILATE
MTRHFEHLAKFVSVFGTDVDAGKETTHDNEDNQILVRRMLIKCADVSNPTRPLKFCVEWA
RRIAEEYFTQTDEEKRKNLPIVMPMFDRTTCSISKSQIGFIEYIIHDMMDAWNSFIEMPE
IIRYMEHNYSKWKLFEEQGINTLNDIKRKQFTLNTSEAAGTTSSVEEL
>A0A7H1KNM7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured Methanosarcinales archaeon|TrEMBL
MDTKRMKIFVPFFIFCLFTSIASGEALYVADNDGPERDITNISDAIKEANYSSFKEINNF
TTFPLDAGNYLFSFAVATDIHWSSSDSISNFGRMYKYTDQLLADVVTAINAESVNFTILL
GNLTDNGLAYEFDNVTKRLNKLDKPFYPVIGNHDKSEGAWVTEWAELGPGNTTYIFNFAG
WHFIVLDTVNDSNTEQGILTDDITKWVQDDLKVHNTMPTIICLHFLVNRLVAN
>A0A2I0DPP5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. GutDb-MelDb|TrEMBL
MLKEAISYSISESGSVRMVQVTDPHLFADPEAQLLGLNTSHSLNAVLNTIAAVDYPAHFM
LATGDISQDYSNQSYHNFVDAITPLNLPCHYLPGNHDDPRIMNLHMQGEKVYGQKRILAG
NWQIIMLDSTVRGRPGGHMSDDELSLIDNAIKAEPNRYTLLVMHHNPVLAGCAWLDQHCM
DNGSDFIEQVSRYRQVKGLLWGHIHQSIDTIHLGPHGPVKLMATPSTCIQFKPKSPYFAL
DALQPGYRLLELKSDGSILTNVYRVPGENFSPDNEAGGY
>A0A287DFA7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ictidomys tridecemlineatus|TrEMBL
LLKQESWNSSVKITTCNKGDKENINDRRSANMMHVNNFPFRRHSWICFDVDNGTSAGRSP
LDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTP
FAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLKELD
WCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVE
IPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWG
LHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNI
HAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIQDVDHPGVSNQFLINTNSELALMY
NDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKXXKKNVLATDMSKHMNLLADL
KTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQ
GDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNR
EWYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDS
KTLCTQDSESTEIPLDEQVEEEAVGEEESQPEAPVIDDCSPDT
>A0A2D4F6F9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micrurus corallinus|TrEMBL
ACRPPRGAAPPCAFPPGQGLPPPRCLGLPPGHQRAAEVDMHFSFSEEDIKRHRLLAKSVS
FEVENGPSPGRSPLDSQASPGLVLHPSFPQSQRRESFLYRSDSDYDMSPKTMSRNSSIAS
EAHTEDLIVTPFAQVLASLRSVRNNFSILANVPTPTSNKRSPLGGQPAVCKATLSEETYQ
QLARETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYIS
NTFLDKQNDVEIPSPTQKDREKKKRQQPMCQISGVKKLMHSSSLTNSSIPRFGVKTDQEE
LLSKELEYLNKWGLNIFRVADYSNNRSLSCIMYTIFQERDLLKTFKIPVDTLVTYIMTLE
DHYHADVAYHNSLHAADVTQSTHVLL
>A0A2D4GV67|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micrurus corallinus|TrEMBL
MKEQNSCVGTGHPPMAGYGRMDPLELAVSPVKRLRTEYSFPYLFAEEAYQKLASETLEEL
DWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEV
EIPSPTQKEKEKKKLPMSQISGVKKLMHSSSLTNSSIPKFGVKTDQEDILAKELEDVNKW
GLQVFKIAELSGNRPLTVIMYTIFQERDLLKTFKILPDMLITYLMTLEDHYHADVAYHN
>B0TU84|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella halifaxensis (strain HAW-EB4)|TrEMBL
MLKAAISYSISEAKSVRIVQVTDPHLFADPEAQLLGVNTAQSLGAVLNTISAVNYPADFM
LATGDISQDYSNESYHSFVDAISPLEIPCHYLPGNHDDPRIMSLHMQGPKVFGQKRILAG
NWQILMLDSTVRGRPGGHMSDAELDLIDSAIAAEPERHTLLVMHHNPILAGCNWLDQHCM
DNGSHFIEKAAQYPQVKGLLWGHIHQTIDTEHKGPHGALKLMATPSTCIQFKPKSPYFAL
DAQQPGYRLLELKSDGSILTNVYRVPGETFSPDKDAGGY
>A0A553JTL6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella hanedai|TrEMBL
MLEEAISYSIDVEASVKIVQVTDPHLFADHDAQLLGVNTALSLQAVLDTIGADHCSADFM
LASGDISQDYSAASYHNFVKAISPLGLPCHYLPGNHDDPRIMRLNMQGPKISGKRRILAG
SWQIIMLDSTVHGKPGGFMSESELELIKSAAEDEPERHILLVMHHNPILVNCAWLDQHWM
SNGNEFLEQVALLPQVKGLLWGHVHQQIDKEYSGHFGPIQLMATPSTCIQFKPKSSYFAL
DALQPGYRLLELNADGSIETNIYRVPGEHFSPDNSANGY
>A0A7U9LSW9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O145:H28|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7K0DLN0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nocardia aurantia|TrEMBL
MGTRLRTVWLANVAVGAAAVTVRTPFRTPAAFHTRTTEPVRTQRQSLVASDLEVVTVTDR
SAVLTWTTRARDGSGRPRPAPADTEVRIAPADGRLPATTYFHATERTPFHYAEIHGLEPG
RSYRFEAYSDGRRAVPARTLVTRAPGTPESTGVFTTLTPPPGVLLRTVVLANDVHYGERT
SGLLVAGFPSGFRDEFAEHPELMLEAVLDDVHRPDRAADHLILAGDLTDSGTPEQSRAVR
DRLDRWGRHGDDWLVCRGNHDAPIAPDNDPWGAAFHARQQLITHEAGGLRLIGLDTTRLR
GSGGTIVTPQLDRLREVLAADPDRPTIVFGHHPVTLSAAVSNPGGPGFVLDRATAAGLHE
LYRQSPGVFLHHSGHTHRNRRGRPDIGIDVEFTEGAAVKEYPGGYLMVRLYTGGYMVNFY
KTRTEAARRWSTRTRRQYLGLHPDHSLGSFADRNHVVLRDLTALSASASLRRSRPS
>A0A8C6QRK3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nannospalax galili|TrEMBL
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQ
KDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIF
NVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAAD
VAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDES
VLENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMV
ETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKE
RERGMEISPMCDKHTASVEKSQVSTTEIFQFLYNSFL
>A0A6L5EEY9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter telavivensis|TrEMBL
MESLLNLSLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHADRQEYDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKCVMIGD
QWQILLLDSQVFGVPHGELSEFQLEWLERKLAEAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDNIA
PGWRTLELFADGTLKTDVCRLQGAEFRPDTASEGY
>A0A1A6KC27|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. UCD-FRSSP16_10|TrEMBL
MEPQIVVTEDTVQLIQITDTHLFGDGERCLLSVNTGLSFQAVVEDIVMKDLSFDAIVATG
DISQDHTTASYARFADGIERLIKPCYWLPGNHDQKSTMSSVLPSEQIHEVGHVLAGDYWQ
LIMLDSQVEGLPHGYLEQQQLQLLEQKLNQYPERHTLVMLHHNSLPIGSAWLDQHKLQKA
HQLWEVLDRHQNVRAVLGGHVHQDFAKEHNGVQVIATPSTCIQFKANTDEFALDTLPPGW
RYLQLHKDGHLSSTLYRLAEGCFVPDFDAQGY
>A0A7W2PRT1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas juntendi|TrEMBL
MHADHPRPVHVVQLTDAHLFADPAGSMLGLKTRESLGHVVAQVRREQPLVDLLLCTGDLS
QDASVASYEAFRELTAPFGVPSRWLPGNHDEARIMAEVAPELVQAVTDIGAWRIVMLNTA
VHGATHGLLGDDQLAVLEAALKGAGGRHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDII
EGYPQVRALLWGHVHQEWDEVRNGRRLLATPSTCIQFAARSEDFKVSEEQPGYRWLRLHA
DGRLDTGVERAWDFEVKLDFDSPGY
>A0A5W7FBQ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Goldcoast|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>V5TWH6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cronobacter malonaticus|TrEMBL
MESLLNLPVAGGASVRILQITDTHLFAGKNDTLLGVNTWESYQAVLAELHAEQRECDLIV
ATGDLAQDHTPEAYEHFATGIASLPAPCVWLPGNHDFQPAMYSTLQDAGISPAKRVFAGD
NWQVLLLDSQVFGVPHGELSDYQLEWLERMLQAAPERHTLLLLHHHPLPSGCGWLDQHSL
RNAQALDDVLNRYPQVKNLLCGHIHQELDLDWNGRRLMATPSTCVQFKPHCAGFTLDTVA
PGWRWLNLHPDGSLTTEVCRLEGAQFRPDTASEGY
>A0A8J6DWC3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Galemys pyrenaicus|TrEMBL
MARPRFPQQQQAVFLAAAAEDEAFLPQPPTPRTPRCPSSPPSSPIFFASPSLTFCRRLRL
LRSFQDFSRQAWAGSSLTACEMGPVVPSGGCLAKRLGDVTVCTGHGEQPSSCVPGGHLAP
MRSTAAPRARPRPPALALPPVGPEPLVHFSFSDEDTQWHPPGRPVSFEAENGPTSSPGRS
PLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPF
AQVLASLRSVRSNFSLLTNVPIPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDWC
LEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLGE
>A0A5I0CTL5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Ouagadougou|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A418SIA3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudooceanicola algae|TrEMBL
MTRILHLSDLHYGRTDPDLEDPLLDRIAALSPDLVVVSGDLTQRARHGQFSRARAFLDRI
TAPVLTVPGNHDTPLDNLFMRFFKPFSRYRKHITRDLEPRFHGKGTSVFGINSVNPYAWQ
TGRLKGGTLRRLGRAIEQGENGHKSGINIAVLHHPLETPPERGRPQMRGAAGALRDLAGA
GTDVVLSGHLHNAHWAPFTSAPGLLFVQAGTGLSTRLRGEENTFNMLDCAPGRVEITAWA
AGSPETPHSFEIRDQATFLREDLGWKRQTLG
>A0A2S9S7T1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNEFDVILA
TGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNVAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLVPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAEFLPNMQEEGY
>A0A554H1C7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. ST1|TrEMBL
MPSAAPSSSVLLVQISDSHLFAEADGALLGMSTRDSLEKVVDLVLAEQPQVDLVVASGDI
SQDGSVESYEAFRRISTQIAAPARWFAGNHDELPQMEHVAQAEGLLEPIINIGRWRVTLL
DSAVPGSVPGFLAAGQLQLLEQSLSEAPDRHHLVCLHHHPVAIGCEWMAPIGLRNADALF
AVLDRFPQVRAVLWGHVHQEFDQMRNGVRLLASPSTCIQFAPGSADFKVDTTAPGYRWLR
LHDDGRLETAVSRVVGMEFEVDYGGTGY
>A0A8E4BQN1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNEFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNVAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTQVKRIQQAEFLPNMQEEGY
>A0A624JJW0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEVRVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>G3TVY9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Loxodonta africana|TrEMBL
WKPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAEPERP
LHRPIERADAVDTSDRPGLRTSRMSWPSSFHGTGSGGAGGGSCRRLLLPEGGSQHSPSRS
SPSLQKTTSLALHSCQPSPCAPRRRAALMRSGTDYSRSPAVSPPSVRVSETHAEDLIVTP
FAQVLASLRSVRSNFSLLTNVPIPSNKRSPLGGPPPVCKAHCQVEGVCLKAVVSLCLSVL
LGIRIYDCVSGLPVLQFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEILSPTM
KEREKQHAPRQQRPPQHPPPPVPQFQPMSQITGVKKLMHSSGLNSASIPRFGVKTDQEEL
LAHVGGAWRGLAGEQEPGFPGVQRNIGIWDTCFIRREDRKERSKHIESKTVFLSSGAQAH
QLLGGHNVLPTDSVSSKSSKVLGKGLGGQVTFSGARMLLTSILHPLQELENLNKWGLNIF
RVSDYAGIKYVGREKSMIYNKTNCPSMYILRCFQFLFIFSFFFFLLVQELWWIWRSKIAG
SSGTNVFFHFCRSHSVVVPSAPGGNVLMLFLLPQVGFIDYIVHPLWETWADLVHPDAQEI
LDTLEDNRDWYYSAIRQSPSPPPEEEPGGPGHPPPPDKFQFELTTTAQITATAQDASTVQ
ELSLAQKVPITAKDTSVIAPAASPAEKLLEVKGQDPSTEVEIEEDQSTSQDTSVALDAVS
CSSPPVLFPESPPLSALRTPPPEEEAPGLLGLPSTAAEVGAQREHQAAKRSCSVCTGTSS
QDPATLPAPSEWGAGGGPT
>A0A5E4MAC0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cinara cedri|TrEMBL
MGCVSSSKDVFEYHYDAIEKTNSDTLGRILHDQTANTDVWNTEIAVRNNNDLTENRLLNI
PSEMWDNCCRRSGSASDLSRDTVDAYSPINRSDSPLAQTPENNYMFGCSKYIQDLRPNPT
LKNILAVTSKEDSVWQSIATTARNLDWTVNRVTSSEEALECFHKGNGVPAVAFVDCRYQN
DKTVDAHQIARSLRSIRKNAHVVLVALVRKSFVVKNEKDVTSILTSGFNKIIVETCNKNV
WIKELQQLEKEDITMRSMLAQQDAVLAALDKTKDLVIITDLKHNIQYMNKSGSMILGYAA
EDVVNKPLAAFHQLGDIDQITKKLEKNIEWDGKVSWKCKNGEHVYLQCRASPFRSFGKET
TNYIYVQESIGEGHGYPRGSVPSIRKGSYDLKSINSDGAQSARRQSLAKLHNLPLEAPIT
KVISLICTAQENSNDQVVQILDKVVDILRVTELYSSHLKTENIKYDDPVTSDLIGALITQ
GPVHVTSTRRSSNDSATVKSQPYGLGIAKMNFMASVTPQIKELLDMALYWDFNVFKLEEL
TMKRPLVHLGMNLLTHFEVHKTLGCDERTLHAWLTVVESHYHAKNTYHNSTHAADVLQAT
AMFLEKDRIKRLLDQLDEACCLIAAITHDIDHPGKSSAFLCNSQNDLAILYNDISVLESH
HAALTFKLTTRDDRLNIFKGLEKDTYKVVRQNVIDMILATEMTKHFEHLAKFVSVCNKPS
TLDDAPIDGLTPSEVSPEILAPTSAEEINLVKRMLIKCADVSNPTRPLKMCVEWAKRIAD
EYFNQTDEEKINHLPVVMPMFDRATCSIPKSQIGFMDYIINDMFETWDSFIDMPEMLYYM
RSNYQYWKDLEEKGTISYSDVCKMPLATTLPKIPESGGNNAEN
>A0A5W4NHH3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enteritidis|TrEMBL
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A2S5CU75|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lysinibacillus sphaericus|TrEMBL
MKKLLYGIFFILFIVIFLYVNNHWLVVSKHVFESEKVPANFDGLRIVQVSDLHDALFGNN
QQKLIAKVKDTNPDYIFITGDVIDSNRYDLKQSLQAVKGLVELADVYYVLGNHEVASNKV
SEIYEALSSLGVHVMANESTVLERDGERLAIIGIEDPLMGRSTEEMLELATAYVPEDMLK
LLLAHRPEVFSTYVNQGIDLVFSGHAHGGQVRIPGMGGLVAPGQGLFPKFTAGFYEEERT
KMVVSRGLGNSSVPYRIFNLPEIIVMDLKKK
>A0A2N5E0L2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chimaeribacter coloradensis|TrEMBL
MESLFTLPVAGDARVRILQITDTHLFAGEHETLLGVNTLRSYHAVLDAIAAQQRPVDIIA
ATGDLAQDHSLAAYRHFAAGIARFPVPCLWLPGNHDFQPAMVDALAGAGIAPSKQALLGD
HWQMVLLDTQVSGVPHGELSEYQLAWLGRCLAAYPDRYTLLMLHHHPLPSGCTWLDQHSL
RNAHELAALLANYPKVTTLLCGHIHQEMDVPWHGRRLLATPSTCVQFKPHCTSFTIDSAA
PGWRYLDLYPDGRLETEVHRLDTHEFSPDMDSDGY
>A0A6P1HGQ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas salmonicida subsp. salmonicida|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQVNEHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VMLLDTQVRGKPHGVLGDHQLAALDSALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRVASQVWRLPVGQFVPDPDATGY
>A0A2P8B065|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micromonospora sp. MH33|TrEMBL
MRIRSRSARLAGVLLLTPLLTLTAPVSPGAAAAAAEPRTPAEDAPAASSRPDSAIALAND
AGVEPAGGLETAKTSRPVAPGLDLTSFDRYDADGWLRADALTADLSGGVTVDYVNSGAVT
RDEPLRAAVDRSRAVAAVNGDFFDINNSGAAQGIGIRSGELVQSPVAGHTNAAAISAEGL
GRVIQVGFEGTAALPAGPVSLTQFNNMVQRDGVGVFTPLWGSYTRKRAVEGAARVAEVTV
TGGRVATVAGTAGEGPIPAGTTVLLGREAGADALAALRPGDPVDLTWRPKASDGSSPRAA
VGGGSVLVRDGVVQSIADQSLAPRTSVGFSADGRKMIMLTVDGRQVDSRGVTQTEMGRMM
VELGAWSALNLDGGGSSTLLAREPGAAAVQVENSPSDGSERPVPNGLAIYAPQGSGRLTG
YWLETASDPTAAPGVAPIRGGRPDRVFPGLTRRLTAAGYDETYGPAAGTPHWRANPAAQG
TVDDGVFRAGRPGRSTVTAWRDEARGTLDLTVLGPLERVDSTVDRLGLNQQGDTGLFGVV
GYDAEGNTAPIEPADLKLEYDHDLLAVTPTANGNLSVRALGGTGAALVTVGVGAKTTVLP
VTIGLTDVPVAGFDDAASWKFSQARASGAVAPAPGHTGTGLKMSYDFSQSTGTRAAYADP
PAWIEVPGQPQAFGMWIKGNGTGEWPSLHLHDAQDTQFVLRGPYLTWTGWRYVEFTVPAG
VQYPVRVRRFYVAETDPAKQYKSEVVIDDLVARVPPTAHAPEEPNITDRVVLRDGTVDGA
PWRFAVMSDAQFVAANPDSDLVAQARRTLREIRAAKPDFLVIDGDFVDTAYPADFALAKR
ILDEELGGELPYYYVPGNHEIMGAPIGNFRSVFGDTSRVFDHQGTRFVTLSTATGSLRGG
GFDQVELLRKTLDAAAADPAVGSVTVLFHHPPRDPSPAKASQLGDRKEAALVEQWLADFQ
HRTGKGALMVNGHVGTFHAGRVDGVPYVINGNSGKDPSTPAQLGGFTGWTEFGVDPVTPQ
EAERARRNPLAEGPRWIAAEFHAHVDRLALAAPAEVAVGAPAAVTATLTQPAGRTVPVAA
PVSADWSGSPNLHIGAAGGVKPWHVARFDPATGQLTALRPGGQVLLVVTVNGVRAEATVA
LTAAAEAPAA
>A0A3N6V0S8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas jandaei|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQANEHPYEVILAT
GDLSQDHSPESYQRFASMMAPLGRPIYWLPGNHDDSPLMTEHLHAAGISESKQLVGDHWQ
VILLDTQVRGKPHGMIGDHQLAALDSALRQYPDRHALITLHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLCDDFALDESGPGW
RYLTLYPDGRVASQVWRLPVGQFVPDPNATGY
>A0A6P8PC93|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Geotrypetes seraphini|TrEMBL
MAQPTASSDTLTVPEVDNSHGPNPWLNEDLVKTLRENLLQHEKSKASRKSPIVSPRLSPI
ISPRNSPRLLRRMLLNSNIPKQRRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQAN
FVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFA
AITNLQDRAPSKRSPMCNQPPINKATIPGVILLKQPQ
>A0A7X2BPF1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. FSL R10-0399|TrEMBL
MPNASTPTTEHSVLLVQLTDSHLFADADSTLLGLNTAQSLQQVVDKARAEQAQVDLLLGT
GDLAQDGSVAAYQRFRQVSEPLCANARWLPGNHDRLAQMREATVQTRLLDPVVDIGNWRI
ILLNSQVPGATPGYLEDEQLQLLARAVSEAPQRHHLVCLHHHPVPVGSEWIEPIGLRNAK
EFWAVLDRFPQVRAVLWGHIHQPFDHVRNGVRLLATPSTCVQFTPGSTDFDVSGEAPGYR
WLRLHPDGALDTGVSRLDNFVFTPDYSANNY
>A0A317Q8M2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mangrovibacter plantisponsor|TrEMBL
MESLLTIPAADEASIRILQITDTHLFAGKDETLLGVNTWSSYRAVLAAIHKEARPCDLIV
ATGDLAQDQSNEAYQHFAEGVSSLAAPCVWLPGNHDFQPAMFSSLKESGISSSKQVLAGK
SWQIVLLDSQVFGVPHGELSEYQLEWLEKKLAENPDRQTLLLLHHHPLPAGCSWLDQHSL
RNAQALDDVLQRYAGVKHLLCGHIHQEMDVDWNGRRMMATPSTCVQFKPHCANFTLDTIA
PGWRWITLHPDGSLTTEVCRLSGSAFSPDTDSEGY
>A0A2H6A0G6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR33|TrEMBL
MKLAHLADLHLGFRQFHRQTPEGINQREADVALAFRRALQDVVACRPDLIVIAGDLFHSV
RPPNGAILEAFVQLSRLRAALPDCPVLIIAGNHDTPRSVEAGSILKLFEEISGVVVATRE
IRWVSLERLDASVALVPHAALAGGVRPELVPAGGSGRQILVAHGEIAGVLPGDRSSLEYG
GVVLEPKDLHLDRWTYVALGHYHVAHRVAPNAWYSGSLEYVSPNPWGELRDEAKEGRAGK
GWLLVALEDAVRVEFRPVPLARRLIDLEPIDGKGREAEEISLLIRQRVERVPGGIAGQVV
RQVVYNVPRLVARELDHAMIREYKSAALHYHLDVRRPPPRREVGVGAPGRSARLEEIVAD
FLRKRVLPPGMDRRRFLELAAEYLAEVEREAVEVGSD
>A0A8B9XBS7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bos mutus grunniens|TrEMBL
MLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVK
KLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIF
QERDLLKTFKISSDTFVTYMMTLEDHYHADVAYHNSLHAADVAQSTHVLLSTPALDAVFT
DLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHC
DIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDR
IQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQETKSGRGEWRSAPCVISTQLLWK
NPRWASSTTLSIPCGRPGRTWCSLMPRTFWIL
>A0A0S7LKV0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
MKKSRSAHGVAPGEENADPLVGQYATGSTLSVEVCKVHRRFSGNLQLPPLSWRQAEKERD
RCRPLTPEEDPMTRTRPTSLPIASLPRIDITQADPDSFEIENGPSLCCSPSDPQASPGSG
LVLHPSQAGHGQRRESFLYRSDSDYELSPKSLSRNSSIVGELHSEDLIVTPFAQVLASLR
TVRNNFATLTNIQCVSNKRSPAANQPSVTKVCLSDESYQKL
>A0A0S7HF21|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
MGLCCSEKQKRNFEMSSSWQKFKRMLNRELNHLSEMSRSGNQVSEYISNTFLDKQNELEL
PCPVQKVRKRKQNQQQQQQQVGMMTQISGVKKVNHTSSILGNVGNRFGVKTDQEELLSKD
LEDINKWGLNIFKVTEHSHNRPLTCVMYKIFQERDLMRTFKIPPDTFVTFMLTLEDHYHS
DVAYHNSLHAADVAQSTHILLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINT
NSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKKQKQTLRRMVIDMVLATDMSK
HMNLLANLKTMVETKKVTSSGVLLLDNYTDRMQVLCNMVHCADLSNPTKPLDLYRQWTDR
IMDEFFHQGDREREKGMEISPM
>A0A6J5FH72|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia fynbosensis|TrEMBL
MKNDYREVLEKTSAHGRREYAWVASRGILILGFVIATYIYLVSVTMYGASLVAAIGASAT
HHNAPFSPMEWALIAMFAAMFVTVSAAWSKIPEMVTFFWTQFEDAVGRIVVPAHSICHIC
FPDRLWFFRKVFVWVAVFIVIAGALACFRWTASQLPALPKNIDVSSALTQFVTPQMFKFV
SGLLTGTIVTALAIRFGFSSKWRMVFEKPECAEAVAPSSVAEHIAHTFRILHASDLHITD
SGDVPLTEGSLRISDDLVSSVLSALARDSQDCAAVLLTGDITDSGSSGSWTRFLDACPVD
LKNKMIFVPGNHDLNLQQGKFPTRAERLDSFGRRMRQIRAMCSMAEVMGERAYLIDRQTR
RLITLATMSAAKALPWKRTSAVICAHAGQ
>A0A2G0QGB9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus hominickii|TrEMBL
MESLLEIAVAEGATARILQITDTHLFANKGDSLLGINTYSSYHAVLDMILEQNLDIDLIV
ATGDLVQDQTIVAYQNFAEGIARLSGPCVWLPGNHDYQPAMVDTLAAAGISPSKQIFIGQ
HWQLIMLDSQVQGVPHGELTEYQLEWMTKCLDEHSDRHTIIMLHHHPLPSGCTWLDQHSL
RNAPELSEILKGKTQVKAILCGHIHQVIDEMWNGIRVMATPSTCVQFKPHCTNFMLDAVA
PGWRYLELSVAGNEEARLQTQVHRLKSSEFCPDLDSDGY
>A0A4R8ELT9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Buttiauxella sp. BIGb0552|TrEMBL
MESLLNLPVAGGGQIRILQITDTHLFSGKNETLLGINTWMSYQAVIDAILAEQRHYDLIV
ATGDLAQDHSAQAYQHFVEGIAEIPAPCVWLPGNHDFQPAMFSSLLEAGISPAKQVFLGD
SWQILLLDSQVFGVPHGELSDYQLDWLERKLSGAPERHTLLLLHHHPVPAGCSWLDQHSL
RNAAELDNVLQKFPKVKTLVCGHIHQELDLDWNGRRMLATPSTCVQFKPHCSNFTLDTIE
PGWRWLELHPNGEVTTEVCRLKGAVFNPDTASEGY
>A0A2A2M7P1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hafnia paralvei|TrEMBL
MESLFQLTVARGAPVRILQITDTHLFAGEHETLLGVNTHRSYHAVLEAIHAEARPYDIVV
ATGDLAQDHSVAAYQHFANGIATLNKTCLWLPGNHDFQPAMVDTLANAGVNPAKHMLLGD
YWQIILLDSQVFGVPHGELSDYQLEWLERTLSLYPQRHALILLHHHPLPSGCTWLDQHSL
RNAHMLGEVLQHYPLAKTLLCGHIHQDLDLQWEGRRLLATPSTCIQFKPLCTNFTIDTLS
PGWRYLDLHPDGTLTTELHRLDGTEFRPDLDSDGY
>A0A7Y2RDI3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter terrae|TrEMBL
MTLSNYNETQQDWTIIQISDTHLMNQEDLEFVDMNPEQSFHAVMKQIQQQYPNVDAIIHT
GDLAQVPVKETYTRYLAFMQRLGIPFYQIPGNHDDMDIFPFYHNQNQVHAIHFGPWSMVL
LNSAVRGKIDGWIEEEQLQQLDQILSKFQQQFVIVACHHHPFDMQSKWIDQHKLKNTENL
TDILARHTNVKAVISGHVHQDSLNEWKNIQFFSTPSTCVQFKPLSDDFALDEEAPGFRVL
HLKANGELQTEIYRTEKASQKINVEISGY
>A0A806X847|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|[Enterobacter] lignolyticus|TrEMBL
MESLLNLPLAGGARVRILQITDTHLFAEKHETLLGVNTWDSYQAVLAAIHASQRECDLIV
ATGDLAQDHSSAAYQLFAEGIAGFAAPCVWLPGNHDFQPAMYSALQDAGISPAKRVLLGE
NWQILLLDSQVFGVPHGELSDFQLDWLEQRLSESTERHTLLLLHHHPLPAGCSWLDQHSL
RNAGALDQVLSRYPQVKNMLCGHIHQEMDIDWNGRRMMATPSTCVQFKPHSANFTLDTIA
PGWRWLELRADGTLTTEVCRLTGAQFRPDTASEGY
>A0A8I3Q649|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Canis lupus familiaris|TrEMBL
MQNAWHTLVLYECTSNVLLHDYVTRIFCFLLSFDVENGPSPGRSPLDPQASSSSGLVLHA
TFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNN
FTVLTNLHGASNKRSPAATSQPPVSRVNLQVAPAKPAASNLSLAASKLESIPG
>A0A8F6R6D6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter hormaechei|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEKRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGD
QWQILLLDSQVFGVPHGELSDYQLDWLETKLAAEPNRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDGVLAKFPRVQNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLAGAQFRPDTASEGY
>A0A2X1QAG6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MERWRFRFISVVKPKDTHLESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESY
QAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMY
SALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLL
LHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPS
TCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A376NV09|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTGFRRLLMSTLLYLHGFNSSPRSAKASLLKN
WLAEHHPDVEMIIPQLPPYPSDAAELLESIVLEHGGDSLGIVGSSLGGYYATWLSQCFML
PAVVVNPAVRPFELLTDYLGQNENPYTGQQYVLESRHIYDLKVMQIDPLEAPDLIWLLQQ
TGDEVLDYRQAVAYYASCRQTVIEGGNHAFTGFEDYFNPIVDFLGLHHL
>A0A8J7F7W4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Plectonema cf. radiosum LEGE 06105|TrEMBL
MKQVYPITIGQVTDMHLFASEQQQLLGIPTMDSFHAVIERLKKLREELDLLLLTGDLSGD
GTPQSYSNLQNLISSLFLPSYWLPGNHDDFATMSEVLNLGLVSRRKCFERGGWNFVLLDS
SVAGKAHGYLRQETLEWLDLQLSKIVDKPTAIAIHHPPFKVNSRWLDKSQLQNSEEFFAV
LDKYPQVRLVLFGHIHQEFYTQRRGVDYLGTPSTCIQFQPGSKKFALERKPPGFRLMKLY
PNGTWESWVERVPYFHTVELVANG
>A0A509EMB3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium symbioticum|TrEMBL
MIRLIPSLPALYVVARVVWPSPWPLALKLGLTAFLLAASQYHLWSRLSSGSVFAPEFPRP
VVILFNVAFGALALAAPMLVALDVVTLVCWILPGDGWTVPMGWRYAAALAALVLAAVAVS
QAVRVPPLKDVTVAIPDLPRGFEGYTILHLSDLHISRLFPAEWAETVVARANALGTDLIA
VTGDFIDGSLAARRTDVEPLRGLTAPDGVWAVPGNHEYFFDYDAWMGHLAGLGIRLLANA
HTVLTRDGGALVVAGVTDRSALSTGHPRPDLAAALAGAPAGAPVVLLDHQPASAARAAAY
GVRLQLSGHTHGGMIRGLDRLVARGNAGFVSGAYRVQGMLLYVSNGTALWPGFALRLGRP
SELTRIILRRSA
>A0A509EFZ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium symbioticum|TrEMBL
MADRATFLHITDAHVSASGAPFERDDRKVDVGGLLAATREGPLELLFRRLAERLTRDSRT
LDGVFFSGDAQSKGVAGGHELVFKLIAEHLGVASDHIVSVPGNHDVPRDADPGTAERYED
FVRVWSAAGCVVPWLDGIDGWPAIAEPGRHRLVAADRSWAVFPINTSNWSHVSSVLPEPL
RSHWNTIPETLEPGDATVAAQLRSQLQALARYDMARVSEHQLEALRALVASTPQPDRGRQ
LRIAVMHHHLRSPSLREELKPFADMSNLEQVRAFLRGSGIGLVIHGHKHEHATYFDHIYA
GDADDMHRVLVISGATFEVGRETDAVRLITLDGLPHTPEVKIEAIPLPRSGAEDLRPAPT
IRRLWTTGVRPAETVLVSPGAPVIVEGTDLDEVYARALAIAGTNAKRGILIVHLDLPDDD
GKTLPLPSAYAVPDDLQGDERQAWLRELVEWWQLDRSQLEPRIPYLHGARLRRYGGKIDQ
IARIIALLRTKPSTRAIAVLVDPFRDFAPNGAGEEFASFCLIEFRRRDADAGRIAVDAIA
FYRAQEFERWWPINIAELRFLQREICEELGYRPGRITTIAADARTISRSPTQVAMPIVDR
WLDQAPERLHLLADALVHKAVRGDAQASAVREWRRSLAELRTATNGFNSDGIPVAIEGLL
TLAAYIEATATVGDAELPILARNLGDLARVNETFEHSTRSRAAFNRWSPVAQSLVTALER
MTDTRLPDDRLKAAGGGEGAP
>A0A8F8G5C6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MSPPDQSRPVHVVQLTDAHLFADPAGSMLGLKTRDSLRHVLAQVRREQPLVDLLLCTGDL
SQDASVASYEAFRELTAPFAVPTRWLPGNHDEAQVMAQVAPELVQAVTDIGAWRVVMLNT
AVQGATHGFLQDDQLAVLEAALKEAGERHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDI
VEGYPQVRALLWGHVHQEWDEVREGRRLLATPSTCIQFAARSEDFQVSEEHPGYRWLRLH
ADGRLETGVERALDFEVQLDFDSPGY
>A0A8I0W1K8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MPQTDQSRLVHVVQLTDAHLFADPAGSMLGLNTRDSLRHVVAQVRREQPLVDLLLCTGDL
SQDASVASYEAFRELTAPFAVPTRWLPGNHDEARVMAQVAPELVQAVTDIGAWRIVMLNT
AVPGATHGLLEDDQLAVLEAALREAGERHCLVCFHHQPVDISCAWIAPIGLRNAQALFDI
VEGYPQVRALLWGHVHQEWDEVRDGLRLLATPSTCIQFAARSEDFQVSEEQPGYRWLRLH
ADGRLETGVERALDFEVKLDFDSPGY
>A0A6I9Z8X8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Geospiza fortis|TrEMBL
MTAKEPARELATPEAEVYIRTFKEQMHLELELPKLPGNRPTSPKISPRSSPRNSPCFFRK
LLVNKSIRQRRRFTVAHTCFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFL
YRSDSDYDLSPKTMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNK
RSPVTSQPPVSRVNLQGRTQTRARSFV
>A0A4R7GRH2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia rhapontici|TrEMBL
MDSLLKLPVASGSKVRILQITDTHLFAGKHETLLGVNTWASFDAVLDVIAADKRHYDLIV
ATGDLAQDHSALAYQHFAEGIARLPAPCVWLPGNHDFQPTMFTTLAASTIADQKQVLVGD
HWQIVLLDSQVFGVPHGELSEYQLEWLESVLAAEPQRHTLVLLHHHPVPSGCSWLDQHSL
RNPHMLDTVLRRYPQARNLLCGHIHQELDLEWQGRRVLASPSTCVQFKPHCTNFTIDAES
PGWRWLDLYDDGRLDTQVQRLTTRIFNPDLDSEGY
>A0A539CUY0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Beijerinckiaceae bacterium|TrEMBL
MLFTDPQPESHAEIDFIRDDVVGGLTGIEAAFGITAGDIMFDDLSLYGRYNRIIGQIGLP
WWNIGGNHDLNFESPSARYCRETYKRVFGSNYYAFEYGDALFLMLDNVDYQGADPTKPRR
AGKYRGFFGERQLGFVANVLRETESTRLVAAFMHIPLRNYLDPDDPSTNVADRAKFLALL
ERRKAVSFSGHTHTTEHHYFGATEGFLDSTPHHHHVLTAVSGSWWSGPLDRRGIASADSR
DGTPHGFHILSIDHGGYTTNFIPANEPNGRQMRISLDAKFHFGTDVFRDFRTGQLRGSPL
GKDQLASVTLVVDVFDGGPKTTVAYKIGENAPIPMKRETRPDPFVQEVFARNRETIKPWV
KAEPSSHIWVARRPLSLELGAHAIDVHVVDEYGRDHHDSLILEVTG
>C5S4I9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinobacillus minor NM305|TrEMBL
MNVFYQLGKDEPVVRLLQITDPHLFSEPSTCLLGVNTHQSLQAVLAEVQKTNVNFHAILA
TGDLIQDHQIQGYHHFARMIEPFKKPVFWVEGNHDEQPQMSLCLSEYPYIQPEKQIFAGN
YWQILMLNSQVAGAPSGYLSRGQLAWLEKSLSENSDRFSLIVLHHNILPTHSAWLDQHSL
KNADKLAKILARFPKVKAILHGHIHQEVNAIWQNIQILATPSTCIQFKPNCDEFTLDILP
QGWREISLFEDGRIETEVKRLKSNDFLPNLEAKGY
>A0A5B8RHW3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured organism|TrEMBL
MESTNSEGARGLAFAHLSDPHLTSLRDLRRRELIGKRLLGYLSWRRGRRHVHCDGILAAL
QRALATHPDEEIAVTGDLTHLGTPDEYREARDWLAALGPGPRVTVVPGNHDLYVPVRWED
TLAEWAAHMCGDGDGDDRPGFPFERRRGPVSFIGVNTAYPSAPLLATGRIDGDQLDGIGR
ALARAGEAGRFRVVLMHHPPQPDAVSRRKSLLAAGRFRALVRRHGAELVLHGHAHRRLRG
EIDGPRGPVPVLGAPSVSQRTHDPARNAAYHRCVVTPTPTGWQLAVTVHAYDTETGDFTT
RADAGHTLEIPRQSA
>A0A330MIN5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aequorivita sp. CIP111184|TrEMBL
MRWFLFIIIYILVDIYAFQVVKTISKSPWIHGLYVFISLGVLAGLIYELSFFGSAKMMEP
PKMYFFGIFLAIFIPKLILVIFMFGEDIVRFFVGVFMKVAGSDQSFYMPSRRKFVSTIAL
GIAAIPFASLIYGMVQGKYNYKVLKYALEFDDLPDEFDGFTLTQISDVHSGSFDNHQKVE
YAVNLINEQQSDVILFTGDLVNNVADEMNDWKALFSTLKAPRGVYSVLGNHDYGDYVNWE
SATEKAENLDKLKSLQKEMGWDLLLNENRYFEKNGQKIALVGVENWGENGFKQAGDLDKA
CEGILETDFKILMSHDPSHWQAKIKDDPRHFHLTLSGHTHGMQFGIEIPGIIKWSPIKYR
YKNWAGIYEEFGRYINVNRGFGFLGYPGRVGIWPEITVIQLKKKQSTV
>A0A4Z0M0P3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haliea sp. SAOS-164|TrEMBL
MSSAADKPRCCLSPAGDSVHLVQITDTHLCEAPGGTLLGMDTDRSLRLVVEQVLRERPHI
DLVLATGDLSDRGSRSAYQRLVDYLGRLSAPSFWLPGNHDNRAEMAAVLAGTGELCEVVL
AGRWQIVMLDSQIPGEVGGALGEAELQRLQAALADGEAQGLYTLVCLHHQPVPVGSQWLD
EQMVADDMAFWELVEAHPGVRGVLWGHVHQQIDRRRGPVALMASPSTCVQFAPGSAGFKA
DDQPPGYRWLELRADGSIETAVSRVTDAEFFVELDSGGYL
>D2T2V0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia pyrifoliae (strain DSM 12163 / CIP 106111 / Ep16/96)|TrEMBL
MDSLLKLPVASGSRVRILQITDTHLFAGKDETLLGVNTWASFDAVLEAVAAERRHFDLIV
ATGDLAQDHAVEAYQHFAEGIARLPAPCVWLPGNHDYQPTMFSTLGASSIADQKQVLIGD
HWQAVLLDSQVFGVPHGELSDYQLEWLERAMAAEPQRHTLILLHHHPLPSGCSWLDQHSL
RNPHMLDAVLRRYPLAKTLLCGHIHQELDLNWHGRRVLATPSTCVQFKPHCTHFTIDAEA
PGWRWLNLDQDGHLETEVKRLNTRKFNPDLDSEGY
>A0A811VHR0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ceratitis capitata|TrEMBL
MCNIELKQILHSIVRPHNVMSTQQALYTALHRLKEVILITDNHLRIQYANRAAERLLNMR
LDEIISKPLADIFVSDVSTIMMHGRKNKEFDEILTVRRKGQEDVSMHVRVIPVACIGRTP
THYVFNLDVPGSHGDFVATLPQAREAPRGSQHSIRRGSVDVRSVASDGLRRTSLAKLTSL
PLEAPITKIINLLSQVQENCSPDEARLIDKVMEFLKREGLYSPQMKEIRTDDPIATDLIG
ALLTGPSLYSSRRSSNDSIIRVSGRQSTCMPAKMKATPHIMELLEESLSWEFDIFKLEEI
TEKRPLLYLGMEMFRRFNVFATLNIDENVCKGWLAIIEANYHSNNSYHNSTHAADVMQAT
GCFLTQLAAKDMGMDHTDEAIALIAAAAHDVDHPGRSSAFLCNSRNTLALLYNDLCVLES
HHASITFRLTLSDDKVNIFKNLDTESFKSVRSVVIDMILATEMTRHFEHLAKFVSIFGSD
EEPKDIVQSEEESSILIRRMMIKVADVSNPSRQPSYCIEWARRIAEEYFTQTDEEKSKAL
PIVMPMFDRNTCSIPKSQIGFIEYIIQDMMHAWDSFIDMPQLVTYMQINYSQWKKFEEQG
VHTLADVKSKQHSLSVKKSAK
>A0A2V1HAF4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia sp. S1B|TrEMBL
MESLFRLPVAGGAKVRILQITDTHLFASQSETLLGINTYSSYHAVLDAVIAQQREYDLVV
ATGDLAQDHSLAAYQHFAAGMKRLPVPCVWLPGNHDFQPAMVDALADAAISPSKQVLVGD
HWQILLLDSQVFGVPHGELSEYQLGWMERCLQAHPERYTLLLLHHHPLPSGCTWLDQHGL
RNPHMLAAILLRYPKVNTLLCGHIHQELDLDWHGRRLLASPSTCVQFKPHCTNFTIDAVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A8C0G4H7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chelonoidis abingdonii|TrEMBL
MCFVHSFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKT
MSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSTKRSPAASQPPVSRV
SLQGMNVICNHLKVSK
>A0A834K059|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vespula pensylvanica|TrEMBL
MGCKSSALECMGNNKRNPGSHNEAQLDAKNPAIGAALGNIDLRLDYLRLDDLTLREIIHM
DAPLDSFYFSDEDDNLDDKLLTDDDEHADMYDIAGEKEMLEEIRRSLEEDADYPAILHER
FIGRTCLSKIARLLFLTISQRQSCYPINDDQYRYGCPLETLSAVSNPYRCHAASMNIPRR
STQPILYVCGSTEDYNNNSNSKSYPWYSSFFDAICGGMSSKWSVHKAKTQMHDLSTLSKN
SSIPITIEKIEMKDLQVKRKKVNKPLTTPRSRRRASIYEQLKSQYLDKDFIGKGPQDIDS
HLLTSSAPELIKILLVFSKDDQQMEILANISRRLGWSVSVAKDAEKAVEIFQTRGHELVI
IDHRGQRAVEGDAICRAIKSSPVYHSSVIIALVKKSYFMNSEKDEIVTLDLLKKGFSRAL
LECSNEGILINELVGIYTSSVLPKTQLAAAHALYLALDRCHDMVHITNERNILQFLNKVS
EKLLGYKTEELVGRNLGEIVHYENFALIEQQLSKGREFEGNMNCKRKNNQMITINCRIIP
FCITPKKATHYIYVYDTLYLLENSGPLSPINSPLQSTQRASILSNRKSSDVKSALSEGHR
RYSLQKLHSLQLEAPITKVITLLSNAITETTNPETAGQIDKAIEILKTTELYVPHLRDDK
IYTDPVATDLVGALLSASRNPWDSRRSSADSARLSHLRGISITSTRGPAKPYRGPQEIME
LLDNSLEWSFDIFKLEVLTEKRPLVFLGMNIMNMYDVPNKLDCDEKVIHNWLTLIEANYI
STNSYHNSTHAADVMQAIARFMQSDRLKQILDPLDEVAALIAAATHDIDHPGRSSQFLSN
SNNRLAILYNDLSILESHHAALTFKLSLSDDKVNIFKNLDRDTYKILRTNIIDMILATEM
TKHFEHLARFMNVCSLRIGEDQPMEYNTENVDVTILLQPDNVMMVKRMMIKCADVSNPTR
PLRSCIEWARRIAEEYFNQTDEEKKLNIPVVMPMFDRMTCSIPKSQIGFVDFIINDMIEA
WDSFIDMPEMLNYMRHNYDKWKEFNDQGITTLQDIEKIQLQPDLKIIKFSEERR
>A0A8J7JU23|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oculatella sp. LEGE 06141|TrEMBL
MSQSPLIVAQITDTHLFADERQTLLGISTTQSLQAVLKRLKTLHPQPNIVLLTGDLSQDE
TPQSYERLRDCIAPLNIPTYWIPGNHDRPHTMQSILNTGCISAEKSVQVQGWRFLLLNSA
VPGQVHGQLSEDTLTWLNQELQQHPTTPTVVALHHSPRPIASDWMDDINLHQPEALFAVL
DRHPQVKTVLFGHIHQEFADQRQGVRYFGCPSTCVQFKPKHSDFAVAQEGPGFRLLELHP
DGSYSTTVERVAYSAELDLTASGY
>A0A8H9ZD36|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. BW16M2|TrEMBL
MHVVQLTDAHLFADPAGTLLGLNTRASLGHVIEQVRREQPRIDLLLCTGDLSQDASVASY
QAFRELSAKLGAPARWLPGNHDEAQVMQAVAPELVQAVTDIGPWRIVMLDSAVVGATFGL
LADDQLAVLDQALDGAGERHCLVCCHHQPVDIGCAWIAPIGLRNADELLRRLRSYPQVKA
LLWGHIHQEWDEKRDGIRFLATPSTCIQFAPRSEEFKVSEEQPGYRWLRLHADGRLETGV
ERAHDFEVKLDFDSPGY
>A0A8G0TGE0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella putrefaciens|TrEMBL
MLKEAVSYSIAEGESVRIVQVTDPHLFADPEAQLLGVNTSKSFAAVLNTIRAVDYPAHLM
LATGDLSQDYSAESYQQFVKAVTPIGLPCHYLPGNHDDPRIMYLHMQGEQIYGQQRILAG
NWQILMLDSTVRGKPGGNMAETQFELIDKAIAAHPECHTLLVMHHNPIVVNCTWLDQHCM
DNGAEFIARVAKYPQVKGLLWGHVHQCIDTHHNGPHGSMQLMATPSTCIQFKPLSPYFAL
DSVQPGYRLLELRADGSINTKVYRVPGNHFSPDNNSSGY
>A0A7R9CRD6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Timema cristinae|TrEMBL
MKTTPYGSADCPPSHVAPFSYRMKVLHVLLVFPKDDFNSDALWYASEKLGYECHLARTEN
AAVEVFESRHHDIIIVDNRYPRVMNGEKVCQNLRAAKGSKFTVIVAVVKRRKSSLDLLGI
DIVNPLPVVGVCTCEEGGLAEKDDPIVHNFLAVGYNRIFLETSSLGICMNELLTLEKSDV
IPRANLAATQAFHLALNKCNELVHITNHEHTIEFVNQAVEYHMGFPRSAMVGKNLMEMCR
LEVNELMVQELQKGREWEGVITWYTRTGERLILSGRVLPFSLPGRPPSLYVYVHESPTMS
EKRSSQSIVPFSQQGFQASAAQRGSITSAGTRRQSLAKLYNLQIQAPITRIIELINSAQE
EAAEPVVQILDKVIDIVRTTELYTPHMKERPIKLTDPVTSDLISALLMVRTSLRLGETLV
PIKQGGTGTTASLTRRSSSESSAFKNPLSIPGSAKGTMYLAGSSKMKDLLDTALNWDFDI
FSVEQISEKSTASYYPFGLYALSTNYASGLGIGKVELEEVNPHLREGRVENHLGKTTPSS
ADRDSNLDLPILSSRAKHEVNQVDLHLSLYVDPRHDLSNRPLVHVGMSLFLHFESHLALG
CDESTLKNWLTIIELNYHSTNSYHNSSHGADVMQAAAGFLKTDRLMQTLDSLDRAICLIA
AAAHDVDHPGKSSAFLCNSDSDLSLLYNDLSVLESHHAALTFKLTMSDERVNIFKGLERD
TYKVVRQNIIDMILATEMTRHFEHLAKFVNVFCKGGIQDEENAEVNLEVHSR
>A0A366MDX9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methanobrevibacter sp. NOE|TrEMBL
MNILAISDVHGAEQKGLYDYLSKNKMDLLIISGDITDFGPLEFVGDFLNKLSKYINILLA
VPGNCDPVEVKNKIDESAAICIHEDVIEYGNVVMYGFGGSNPTPFDTPGEMDEDTLYNSI
KKIIDSKSIESIKKPSENFPYGKVSILITHAPPKNTETDKISSGAHVGSESIRRIIKEYN
PRINICGHIHEARAFDILDETTIINPGALSDGYGCLIEIDDNNNVIGNFVELK
>A0A7X6E8G1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. BG5|TrEMBL
MPSVSTLTTADTALLVQLSDSHLFAEADGTLLGMNTRESLQKVIDLVLEQQPRIDLIVAS
GDLSQDGTLESYQLFRQMTAQIDAPARWIPGNHDEPQIMAQATVKSALLESVVDVGNWRV
TLLDSAVPGSVPGYLQDDQLQLLARSLSEAPDRHHLVCFHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQARAVLWGHVHQEIDRERNGVRLIASPSTCIQFEPGSEHFKVGEQAPGYR
WLRLLPDGRLETGVERVTGFDFQVDYGSNGY
>A0A5I0UWL3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Hvittingfoss|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5R9LD06|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella indica|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYRHFAEGIASFVAPCVWLPGNHDFQPAMYSTLQESGISSAKRVLLGD
HWQILLMDSQVFGVPHGELSDFQLEWLEQKLAQSPDRHTLLLLHHHPLPSGCSWLDQHSL
RNAGALDCVLSAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLDLHPDGTLTTEVCRLEGVKFHPDIASEGY
>V4NCF6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurella multocida subsp. multocida P1062|TrEMBL
MFSTYRYDTSAEVFKIIQITDPHLFKDEHGELLGINTFQSFSQVLHEIKASRFDYDLVLA
TGDLVQDSSREGYLHFCEQVKSLEKTVFWIPGNHDFQPKMFEILNQDQGNLNPKKHILLG
KSWQILMLDSQVFGVPHGELSQYQIDWLVAKLKDHPERYTLIVLHHHILPTHSTWLDQHN
LRNAHELAYALAPFDKVKGILHGHIHQEMDANWQGYRVMATPATCIQFKPDHNTFTLDSV
QPGWRELELHSDGRIETRVKRIQDKTFFPNMHEDGY
>A0A849B0F6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. ANC 5378|TrEMBL
MTLSNYNETRQDWTIIQISDTHLMNQKDLEFVHINPEQSFHAVMKQIQQQYPNVDAIIHT
GDLAQVPVKETYSRYLAFMQRLGIPFYQIPGNHDNIDLFPFYHNQNQVHAIHFGPWSMVL
LNSAVRGKIDGWIEEEQLQQLDRILSKFQQQFVVVACHHHPFDMHSKWIDQHKLKNTENL
TDILAKHPNVKAVISGHVHQDALNEWKNIQFFSTPSTCVQFKPLSDDFALDEEAPGFRVL
HLKANGELQTEIYRTEKVQQKINVEISGY
>A0A182LS27|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles culicifacies|TrEMBL
LALTPEEEPLDSCPRLVSDLKFPNLLPPNPVIKILIAFCKNDPVFDALVNASHRLSLEPT
FVKSAESAIEAFQNPSSGGHHIIIVDARYPRTMEAEALGRSIRNSKGSQHTTMVAVVKKS
VFEKDDTAVISLLDVGYNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQALYTALHR
SREAVIITDDTLRAQYANRASERVLNMKLDEIVGRSLNDLVTADISNILSHTSRYKDYDG
YLTTRRKSQESSQIHVRAVPVSCIGRNPTHLVLILESSSSALVSSNAIGEALQTLPQGKE
VPRGSLHSIRRGSFDVRSIASDGLRRTSLAKLSSLPLEAPITKVLSLLAQVQENCSLEEA
KLLDRVMEFLKREGLYSPQMKEIRTEDPVATDLIGALLTQGPTNILSSRRSSNDSIIRGG
GRPSTGSIVFNKTKESSELSDLLQTALDWDFEIFKLEELTEKRPLVCLGLELFRRFDVYA
TFNCDEMTFKLWLIEMEKHYHSENTYHNSTHAADVMQATAVYLQQLSNRELKIMDRMDEA
TALIAAATHDIDHPGRSSAFLCNSDSSLALLYNDICVLESHHAATTFRLTLADDKINIFK
NLDRDMYKLARSIIVDMILATEMTRHFEHLAKFVSVFGTDVESKEPLAPDNDDNQILVRR
MLIKCADVSNPTRPLKFCVEWARRIAEEYFMQTDEEKRKNLPIVMPMFDRTTCSISKSQI
GFIEYIIHDMMDAWNSFIEMPEIIRYMEFNYSQWKLFEEQGINTLSDIKRKQMSLNEETA
SSISLEEKF
>A0A8J6ST64|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oculatella sp. FACHB-28|TrEMBL
MLPPSPLLIAQITDTHLFAGKSQELLGLPTAKSLNAVLSCLQKLQPQPDLLLLTGDLSQD
ETVESYYCLYQFLLPLKIPVYWLPGNHDVPSVMEQVLNTAPISAEKTFQRGGWNFVLLNS
AVSGRVDGKLSSQSLNWLEQQLQANPHPTLLALHHPPFPIGSNWIDEINLQNSADLFAVL
DRYSQVKLVLFGHIHQEFDHWRHSVRYLGTPSTCVQFKPNSANFALDQLKPGFRLLYLDP
DGNYSTRVERIDCVNQLDFAATGY
>A0A6P1RLL1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium odoriferum|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKARQDAFDLIV
ATGDLAQDHTLQAYHHFSRGIVQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSAVLDRYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A6I9Q525|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Notothenia coriiceps|TrEMBL
MAQEAGMGVTLQDTLAVPPMPKHSGLNEDLVKILRENLLQPERPRGQRRSPSSISPRLSP
RNSPRLLRRMLLNNNTHKQRRFTVAHTCFDVDNGTSSGRSPLDPMASPGSGLILQANFVH
SQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALT
NLSQDRAANKRSPMCNQPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEM
ASNKVLEMNSDTWFPERLISDSPNGDSLKERQYSELALMYNDSSVLENHHLAVGFKLLQE
ENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNY
SDRIQVLQNMVHCADLSNPTKPLQLYRQCTDRIMEEFFTQGDRERERGMEISPMCDKHNA
SVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYSSTIPASPSPTLDDPED
GTRPPGGDKFQFELTLEEDGESDTEKDSGSQPEEEEEEEELEDEDDDEEEDEDEENSCTD
SKTLCTQDSESTEVPLDEPLGDDEEEEVAEEGETPCTQTCVVEEEVAEEGEKEEPPHT
>A0A3L8B7S0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ketobacter sp|TrEMBL
MRIVQLSDCHLFKSTEGKLLGLNTEQSLALVMDLIQDQQHAIDLVLATGDLSQDGSSESY
ARFHQWMEAFSCPVYWLPGNHDLTDIMANHQAAQRMSPCVIDAGNWQIIMLDSTIRGKVP
GNFAASELQFLQQALQASTGKHVLIALHHQPVPVGSAWLDQQIVGNAAEFFKVVDQFTNV
QAIIWGHVHQVFETRRNGVQLMSVPSTCVQFLPNSKDFAVDKTSPGYRWLDLHADGTIGT
GVSRVTGVDFVVDYSVKGY
>C6DIS6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium carotovorum subsp. carotovorum (strain PC1)|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKARQDAFDLIV
ATGDLAQDHTLEAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALAEAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHSLSAVLDRYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLFPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A602YVC8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Pensacola|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>L5K6X2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pteropus alecto|TrEMBL
AFSLSFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAM
SRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTILTNLHGASNKRQTLRNDITHPKEP
QDD
>A0A5M9N980|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio gigantis|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQDFDYEAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNALVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPHGQFLPDFEAAGY
>A0A7W4QHK3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacillus velezensis|TrEMBL
MKLVMTLFFLICLLCVSPSADAARKEPAIPVNQQEFGQPPHYIPLLENPPQIEVKAEMKR
NLFIQAHVRNADYQAFSAFLFYKQSNELGFKMVPMEPAPGAIRLFTAQVSKRDIWNGELE
YYLVFTNGRQRAESEKKRLKLDGYQADLNHIPELMITELAVDTKNEDGADAYEFIEVYNT
TDRPIHFKDYHIRYRYPKEGPESDMIWRPKEDTVIPSGGTYVFWLRRAASELTIDDFNRY
YGTRLKEGKHLAVIEGTDGMSNDRPRTVVLSANTGKTIASAHYRKHAFRRLTSLLYKYPL
NGTGELLKISTSEHKPSPGSVFQAQIPEQKRVIKPDKEKPVIEDLTDRKPVRPAESIELK
ADIKDKNLVKTAAFYYRTNEKKPFKRILAEKDRNDRLYRHILYSPELLGQDQLEYYIAAG
DGENEAKTPVKMIDIKQTSKSHGLRMNIEPEDTISGTYLLKATSDVSADKIKLWIDGKLQ
ETRPALEKEVYFAFDARKTNLYFQNTVMMENEVLHIFDDPAHRYRTYSVLLPERLLQKGG
KTQKVSIRSGSKVSPYDIGENRDDFIVKNARLVLSDGTVIKNGERDPAEQLFIGDGKRAN
QRMTFSFSLPDHLFTSRLLPWNTVKLSEGHHHIFVSDGEEQLSQSVLVDNTGPKIVPGIK
EGATLKGNFELKADIRDKWSKVEEVKAFLDGESITLPHHTSSADLKPGKHTLTITAADLA
GNETTSVRTFHIKREEPNQPEFTGQKTGAHKAKLSVRVKDPTKDEMNVSFYRGFRYTARN
PGSVKVYQHASLTEPPRGMKENEMPFTLPEMNRISANDGKTVSTENMERFPYHRFEVSVD
PSIDETDRAEAVWKGSSLPGRKVTMYIWNYRTSRWQEADSVLAKNKKPFTLKAAVSAADA
VKNSKMNVIVQDQIPAKGNYSFVWMSDTQYYAQGHPHIFDKMTEWIKENKEKHNIKYVFH
TGDIVDDSMVMKQWKNADHSMRTLDKAGIPYGVLAGNHDVGHKDGTYRTFGDFFGSRRFE
KKMHYGGSYKNNRGHYDLLSASGNDFIMIYMGWGITDQEIDWINQVLKRYPDRTAILCFH
EYLLVSGNRSPIGETIYRKVVKPNRNVAMVLSGHYHNAMKKTDALDDDGDGKPDRLVHQI
LTDYQDGPEGGQGFMRMMQFDQAANQVHMFSYSPYTDDINYYDTDLFADKDEFSAEMDLQ
PKRKRVATDYFECNVYTNELLGHKKHVKSGKTANWIWDGLQPDSVYYWYTVVKDPYNGKT
ISPLWMFKTGNTPYRPAPDQFDFRHASNP
>A0A7Y8JNA0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas yamanorum|TrEMBL
MPSVSALNPDASALLVQLSDSHLFAEADGGLLGMNTRDSLQRVIETVLAQQPQIDLVLAT
GDLSQDGTLASYQAFRDMSRQIEAPARWIPGNHDEPQVMQQAAINSALLEPVVDVGNWRV
TLLDSAVPGSVPGYLQDQQLQLLAQSLSEAPTRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERVEGFAFQVDYGSNGY
>A0A3Q9JI75|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microbacterium oxydans|TrEMBL
MSHIASQHPAPEHFILHVSDTHFVGDGDLLHERIDSDKNLAELFDGFTKANARPEAIVFT
GDLADTGRPDAYERLRAIVEPAAEKLGAQVIWVMGNHDERVAFRRGLLDEEADQSEPVDR
VYDVNGLRIIALDSTVPGQHHGEISDEQLAWLRRELEVPAPDGTLIALHHPPVPSPLGLI
ALFELRDQERLAEVIRGTDVRGILGGHLHYSTTSTFAGVPVSVASATCYTQDLAVAYPGA
RGQDGGQSYNLVHVYGDRVLHSVVPIGQFPTVYEMTPEMLEAFMNMTPDEQLAAVNASAG
E
>A0A6M1YGE1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chlamydiae bacterium|TrEMBL
MSKISLIFLLFSCAFGDILFLTANESLENTIIIQILSKKSKAKTVAIENAVQTLLPKPLK
DTNYYLFTYFVHNLRPNTRYTFNVDKKPFSFHTPNPEAFRFAVAGDSENNDTTKHFLKLI
AHQNPAFFIMGGDIAYPNTHFFFFLPYKLIQWLETYSQTMIKDNGDLIPILGVIGNHDVK
GEYDKTPKEAEVFYTLFFPKIQRSYYAFTIGSAYFLMLDTGHTQKIDAKQLEWLSSHLFN
NTHFPTFIFQHVANYPSNRFFNSRSTRLRKLWTPIFDKSNVTAVFEHHDHAMKRTYPIHN
QKVHKNGIVYFGDGCLGVTPRRAKSRWYIEKGWKKNGFWLVDVTPNGYKATAIGKKSVLD
RYELTLRDKSNLRTGCKRQSTTSYSSLNSLGVELHRNPCILPFSLFP
>A0A5E4XN44|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea terrae|TrEMBL
MSDIPSPQPRRRAMSARPRMLFLAVFALLHAYIGWRLLPVLPVAMPWKVLGALGLAASCV
LIPVGMMGRSIQKQPLSDYLSWAGMLCVGIFSSLFVLTLLRDAMLFVVPLFTPVDTQLVA
RSAVLVLILAAFATVVGFFNARRLAQVVEVDVPLAGLPAALHGFTIAQISDIHVGSTIKR
GYVDAIVDAVNALKPDMVAVTGDLVDGGVSALSEHTAPLARLCARHGAFFVTGNHEYYSG
APAWTTELRRLGLNVLENAHVVLEHDGAALVVAGVTDFSAHHFDPAKRSDAQAAIAGAPQ
GMPRILLAHQPRSAQAAEAAGFDLQLSGHTHGGQFWPWMYFVPLQQPFVAGLHRLNRLWV
YVSRGTGYWGPPKRFGAPSEITRLRLVPAKG
>A0A643CIX2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Balaenoptera physalus|TrEMBL
SHWDIAGTASSLTLATLSSGSPGDIRSWKHKQQGPREPLLPILASGLLLTLEAENGPTPS
PGRSPLDSQASPGLVLHSGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVLASLRSVRSN
FSLLTNVPIPSNKRSPLGGPTPTLEELDWCLEQLETMQTYRSFKRMLNRELTHLSEMSRS
GNQVSEYISTTFLDKQNEVEIPSPAMKDREKQQVPRQRPAQQPPPPGPQFQPMSQITGEL
ENLNKWGLNIFCVSDYAGGRSLSCIMYTIFQERDLLKKFRIPVDTMMTYMLTLEDHYHPD
FLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLA
TDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYADRIQVLRNMVHCADLSNPTKPLELYR
QWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHP
DAQEILDTLEDNRDWYYSAIRQSPSPPPEEEPGGPGHPPPLDKFQFELTLEEEEEEEVST
APGAVEVQELSTAQDMFPAEEPLEVDGQDQSTEVEVEEMYWTQQADSADSVAKGQDASTP
PDASVGCSSPPALSPESLLLPVLRTPPPPEEDPGLLGLPSTAAEVGAQKEDQAAKRACCA
CTGTSGEDPSTLPAPGGSEHTVL
>A0A091QJF5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Merops nubicus|TrEMBL
VSLLSPSQFKRMLTRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKK
QQLMTQISGVKKLMHSSSLNNTSISRFGVKTEKEDHLAKELEDLNKWGLNIFNVARYSHN
RPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVAQSTHVL
LSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLA
VGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSS
GVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEIS
PMCDKHTASVEKSQV
>A0A6P4I6X5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila kikkawai|TrEMBL
MRNCLPKFSHVFRRKSKSSALGQENPTEPDSDSEPYVAAVAPPAAATMAISQPRRDSPNE
RPMPDDDSASSRLISSPHLDSKTNLDLDSPAAGGQGSCPEMKLETISATAPPVAISLPFG
GRNSSKTPEEMELEYEASVAAEGRDIMTPLRRNTRPLSLAFGSGRSTGVGAGGVAGTGVM
QPEIVEVIRSLDVPALLLNSLSLEADPREPGAELECDSSEETVVLRRKVNCLERKTRSLY
ERRLPKVPKLHLQVAAKKTSEEEEFRTFQRNLMDLKYPTVLPPNPQLKALLVFHKADSIC
EAVTAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSAKNLDAEHIARTIR
HTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRP
HNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLNMRLDEIISKPLADIFVSD
LSTISEQGKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQMDF
IATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQV
QENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRRSSN
DSIIRTGSSTRTATIVPAKMKANPIIMELLEESLSWDFDIFKLEEITDYHPLLYLGMEMF
RRFDVFATLNIDENVCKAWLAVMEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDMLV
MDRMDEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLGD
DKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPREQHSQTEEET
SILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRATCS
IPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLADIMAKQPP
VGKMANSK
>A0A5E4J3K2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MATYFPLQGFILILGIIAFGATYLIFKTFYKIFRLKTNALFYFIVIASALLFVIGSALET
LHTEITRELYVASAIWAGTLFIAFWIVLLVLLASIFVSIQNKTFGFVLIGIIILLSIYAV
YHSSDTQIHETSLTTKKFNESLKIVELSDLHLGAVRSTSFVRKIVDLTNSANPDIVVIAG
DLFDGTGIYDENILSPFNDIKVPTYFILGNHDIYTGTEVVLKYINSTQIHVIRNNKVDYR
NIQIIGIDDSSDPLQAPDRLENISFDKNKYSILLYHRPDGFEQVSNEGIDLMLSGHTHAG
QIFPFGILENLLLYKHLSGEYSYNNSNLIVLEGVGTWGPPMRLGTDSEIMLIKINS
>A0A5E4HYX5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MSEMRILAFSDIHADEDALDRLRVLASRDIYDLVIFAGDMTNRGPISYAQDLIELFGERF
YFVHGNMDSSAVVDSLRANPHYLHGRKLPLGEWNLVGLGGSNPTPFQTPSELGETQIEHI
LKSVGLDERSILVSHPPPYGSFDQVGGMHVGSKAVAAAIEQFHPLLVLCGHIHEHEGQQI
TGNTLVVKLGAANARRAADIKLGDEIDVSFISF
>A0A5E4HMF0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKLLALSDLHGDYSHVESILDKADDIDAVLIAGDITDFGPDEKALELLGMCKFPVLAVPG
NCDNPSFLKILDENENTINLHNSSHTIGDLTFIGLGGSNPTPFNTPFELSEKKIGEYVGT
LLGRSKGRLILLSHAPPKNTTDKLPHGNVGSAALERDLKRFDLIVCGHIHEARGIVRVNS
TQVVNPGMASKGQGAVITIGEKINIELIDA
>A0A508T9F8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bradyrhizobium ivorense|TrEMBL
MSSAMSERPDKFTFAAIGDLHVKEDRTLSFRQLFAEVSTKAQVLVLCGDLTDLGKPSEAE
LLAEDLRACSIPVIGVLGNHDYESGRTEDVKRVLKGAGMHLLNGQSYEINGVAFVGVKGF
IGGFGRRMLASFGEAVVKDLVAEAVNEATRLENAMRAVASKQAVVVLHYAPIPDTVEGEP
PEILPFLGSSRLGETIDRFKVSAVVHGHAHQGRYEGRTPGGARVYNVARSIEKPTGRPYA
LIEV
>A0A8C3QNX5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyanoderma ruficeps|TrEMBL
MTAREPSRESAAPEAEVYIRTFKEQMHLELELPKLPGNRPTSPKISPRSSPRNSPCFFRK
LLVNKSIRQRRRFTVAHTCFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFL
YRSDSDYDLSPKTMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNK
>A0A5Q5E3U4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. CRENT-193|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEKRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGD
QWQILLLDSQVFGVPHGELSDYQLDWLETKLAAEPNRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDGVLAKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLAGAQFRPDTASEGY
>A0A8C1DMM2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyprinus carpio|TrEMBL
MTRFYCTSLATNLGAHMSFWEMYSKRRENVQLSVQTLFLCKENLYFFFVLNYCFCTVVVF
LFVCFITPFSLFLCSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDS
DYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQQDRTSNKRSP
MCNQPPLSKASFTALSGIQRQRVFAQSLAFLSCGIHSRV
>A0A858BHD9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rodentibacter heylii|TrEMBL
MRNTFVYRTEKSIVKLLQITDPHLFKDEKNELLGVNTQASFAQVLKEIQQDNTEFDVILA
TGDLVQDSSDEGYQRFVKMVKPFGLPVFWIPGNHDFQPKMVENLNQPPMEKAKHILLGEH
WQVLLLDSQVYGVPHGELSQHQLGLLKATLEQYPERYTLIVFHHHLVPTNSAWLDQHNLR
NSHDLFDVLAPFKNVKAILYGHIHQQVDSRWQDYQVMATPSTCIQFKADSQYFALDKIQP
GWREIALYPDGSITTQVKRIQQTMFLPNMQEEGY
>A0A6I6QBJ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas mediterranea|TrEMBL
MPSVSTLTTADPVLLVQLSDSHLFAEADASLLGMNTRDSLRAVIDLVLKQQPNIDLMLAT
GDLSQDGTLQSYEAFRQMSARIDAPARWIPGNHDEPQVMLQAAVQSTLLDPVVDIGNWRI
TLLDSAVPGSVPGFLAEEQLILLANALSEAPERHHLVCLHHHPVSIGCEWMAPIGLRNPD
ALFAVLDRFPQVRAVLWGHVHQEVDQVREGVRLLASPSTCIQFEPGAVDFAVGEQMPGYR
WLRLLPDGRVETGVERVVGFEFVVDYGAEGY
>A0A8C2V7A2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chinchilla lanigera|TrEMBL
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQ
KDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIF
NVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAAD
VAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDES
VLENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMV
ETKKVASSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKE
RERGMEISPMCDKHTASVEKSQVLCPNVLSSSFL
>A0A6M8RAE9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteus vulgaris|TrEMBL
MESQLELSVKHKNTVRILQITDTHLFANVEDTLLGINTYRSYHAVLNAIREQGLDVDLIV
ATGDLVQDQTFEAYQHFADGIATLTPPCVWLPGNHDYQPAMIDALNQAGILSAKQVLIGD
NWQMLLLDSQIQGVPHGELSDCQLDWLTRCLESQKHRDTIILLHHHPMPSGCTWLDQHSL
RNSQELAERLRNHSQVKMMLCGHIHQEMDEMWNGIRLLATPSTCIQFRPHCTNFTLDTVS
PGWRYLEMSLSSDEKGKIETQVYRLAGTEFCPDLDADGY
>A7MWN7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio campbellii (strain ATCC BAA-1116 / BB120)|TrEMBL
MRSSSDSIKLLQITDTHLFEADEGSLLSVRTADSFAAVVQEILNHQVQYEYILATGDISQ
DHSAESYQRFAEGIAPLKKDCFWLPGNHDYKPNMGSVLPSPQIQAAEHVMLGEHWQLVLL
DSQVVGVPHGRLSDQQLALLEEKLAENPQRHTLVLLHHHPLLVGSAWLDQHALKDADAFW
QVVDRFENVKGILCGHVHQDMNVLYNGIRVMATPSTCVQFKPDSDDFALDTESPGWRELE
LHSNGDITTEVNRLPDGQFQPDFNSNGY
>A0A0K8TN27|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Tabanus bromius|TrEMBL
SISHISTSTPQRDAVSTAEEGTSGGSSSSGRIGHRKSSLALTPEEEPSDSSNMRPLTDLK
YPTVLPPNPQLKALLIFHKADSVCDTFSAACERQHVDVTLVKTKESALEAFQNNTAGSHH
LIIIDSRHPKHNYGEDIARAVRHTRGCHFTTIIAIVKKSFLEKDEASVNALLDAGVNRCI
AETQNISLCCTELKQILHSIVRPHNVMSTQQALYTALHRLKEVLLITDDSLRIQYATKSA
ERLLNMCLDEIISRPLSEVFVSDVSSINAQGRGVREFDGILTVRRKGQEGMPMHVRVVPV
ACIGSSPTHYVFNFDLPGGQSDLIASLPQPKEAPRGSLHSIRRGSFDVRSVASDGLRRTS
LAKLQSLPLEAPITKIINLLAQVQENCSAEEARLIDKVLEFLKREGLYSPQMKEIRTDDP
IATDLIGALLTQGPSQLYASRRSSNDSIMRASTSRPSGILPSKMKANTEVMELLEESLAW
NFDIFKLEEITEKRPLLYLGMEIFRRFDVFTTFNADENTFKNWLAVMESHYHSQNSYHNS
THAADVMQATGAFINQLQAKDLSMDRMDEAASLIAAATHDIDHPGRSSAFLCNSDSPLAI
LYNDICVLESHHAATTFKLTLGDEKINIFKNLDKETYKQARSVIIDMILATEMTRHFEHL
AKFVSVFGADVEPKEIVQCEDDNQILIRRMLIKCADVSNPARPLTYCVEWARRIAEEYFT
QTDEEKKKNLPIVMPMFDRATCSISKSQIGFIEFIIQDMMHAWNSFIEMPELIHCMQYNY
SQWKKFEEQGIHTLNDIKAKQISLSAKKSIAK
>A0A433CR69|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp|TrEMBL
MAFQVSTLSQKDFVIIQITDTHLLEYPHLEFVGMQPEQSFRAVIDLMRQQHPQIDMIVHT
GDLAQSPTPVTYHRYLEHMQSLGIPFFQTPGNHDDVAHFPFHESDPNQPTVVEIGDWCII
LLNSAQPKRIDGKIAAAGLEQLTELLKQYHDRHIIIACHHHPFAMQSTWIDQHKLKNSSD
LLETIQPFSNIKAILCGHVHQDSVNTWQNVVFLSTPSTCIQFKPQSEKFALDEEHPGYRY
ICLKANGEFETKVYRLPTSQRTSSSEVLGYD
>A0A485P1K5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lynx pardinus|TrEMBL
MRSGTAPRARPRPPDLTLPPAGPESLAHFSFSDEDTCWHPPGRPVSFEAENGPTPSPGRS
PLDSQASPGLVLHAGGAISQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPF
AQVLASLRSVRSNFSLLTNVPIPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDWC
LEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIP
SPTMKDREKQPAPRQRPSQQPPPPGPQFQPMSQITGVKKLMHSSSLSDSSIPRFGVKTNQ
EELLAQELENLNKWGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFRIPVDTMVTYMLT
LEDHYHPDVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPADSELALMYNDESVLENHHLAVGFKL
LQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDK
HTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEE
EPRGPGHPPPPDKFQFELTLEEEDEEEVSTAPGAFTVQGLSVAQDASPAEELLEVDGQDM
PTEVKVQEPCCTQQADSAGSVAAGKDKATSPDASVDAVGRSSPLALSAGSPLPPALRTPP
PPEDTPGLPGLPSTAAEAGAQKEHQAAKRACSACTGTSGEDPPPLPAPGGWGSAGGPT
>A0A7V2S8V3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonadales bacterium|TrEMBL
MNLNLQNATYQLTPATANNVSPVTIIQLTDTHLFKEKSGKLLGLNTHKSFQAILEHIAGS
APADLILATGDLAQDGSSDAYRRLSSALSSLNMPSFWLPGNHDDPDVMAQSMINKFVFSQ
KRILIQNWQIILLDSKVDNKVHGQLSSEQLDFLHACLSDKPEHYALVALHHQPMNVGSKW
LDGIGLKNSAEFFAVMARHSQVKGVMWGHVHQEFEKNMGQVKLFSTPSTCVQFQPGSEDF
EAGMQDPGYRRLQLLSDGSIESEVIHIRPLDFKVDYSIRGY
>A0A1Q9PCL8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Heimdallarchaeota archaeon AB_125|TrEMBL
MKFSIIGDLHGSLVYLRCIKRKIRKTDALFITGDIAGTLSYRLILKSILKNKKISRENYA
ELVYGKYLTQFVNFQRKTAKRIFKILSKTKIPVFFTHGNSDSEAMIEFFKKYSEKNTLFH
YLGKSTIKHNNLIVAGYGYCSPAEYRTPFQTPGEKSKSEIVEDLSLLENHISKHKKNKND
LIIGLFHEPPKNTKLDFIEWKSTHSGSELIHAHTQDVPYDLILAGHIHESQNYEIQENEI
LVNPGPLVNRKWAIVDIKNKTVSLKKIPIILSAKGFIYRTRETFK
>A0A653XPE5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Plantibacter sp. T3|TrEMBL
MTSDVRFGQYPAPARVIVHLSDPHLLADGRRLYDAVDVQANLEQALRQIERMQLRPDAMV
FTGDLADLGEADAYRRLRERVEPVAERLGTTIVWLMGNHDERSVMRTELLDLPAGEQPLD
AVWDFGGLRVIGLDSTVPGWHHGELEDSQLEWLESVLATPAPLGSILAMHHPPVPSSIPF
FDILELRDQHRLEAVLRGSDVRAILGGHLHYSTSSTFAGIPVQVASASCYSMNLSLPSVE
VNGMFGGQSFNLVHVYDDRITHSTVPLGDYTTADTFSAAFIDRMAALSPAERLEAFSRKR
>V0X1R3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli 908525|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A446CVP7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter veterisilvae|TrEMBL
MSLRQSSFFLRFLTLGALAHVYVGVRLIPDALLGGEGSAAAILALVLSCVLIPLGMLGRS
SVHPPWGDRIAWVGLFAMGLFSSLFVLTVLRDALLLAAWLATLPLDAAPPWPLLRQASAW
AVAALALAGTLVGLYNARRRARVVDVDVPIDGLPPDLDGFTIVQISDIHVGPTIKKRYVQ
AIVDAVNEQLPDMIAITGDVVDGSVEHLGAQASPLGQLRAPYGVYLVTGNHEYYSGAASW
VAEFRRMGLRVLMNEHAVIHPAGLPVVVAGVTDYGAGAYDPQQRSNPRAALSGAPADALP
RILLAHQPRSAAEAEPLGYSLQLSGHTHGGQFFPWGFFVRFQQPYTAGLHRMGNMWVYTS
RGTGYWGPPKRLGAPSEITRLRLRAAPAR
>A0A5F1FAA3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. E4930|TrEMBL
MESLLTLPLAGESRVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADSRFQPDTASEGY
>A0A2S6RKM4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alphaproteobacteria bacterium MarineAlpha9_Bin6|TrEMBL
MLIAHFSDMHVTVDGEFAFEEVDTAGALERCIQHVNALDPAPDVVLITGDLTFNGDIQEY
ATLRAHLSILDAPYFLIPGNHDRRDRLRAAFADLAYLPIKSEFIHYVVDDYPLRLIALDT
VHPGRVGGVLCEDRLEWLEHKLSINNDKPTIILMHHPPFKTGIEYMDRTGLANASSFANI
VSKNNQIRLILCGHVHRPIQTNWSGAAVMTAP
>A0A8A1DFZ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas dhakensis|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRIASQVWRLPVGQFVPDPDATGY
>A0A5E7SDP4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPRVSTLTTADPALLVQLSDSHLFAEADGTLLGMNTRDSLQHVIELVRLQQPRIDLIVAS
GDISQDGTLESYQQFRDLTRQLDAPARWIPGNHDEPRIMAEAAVQSALLEPVVDVGNWRV
TLLDSAVPGSVPGYLEEEQLQLLARALSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPD
ALFAVLDRFPQVRAVLWGHVHQEIEQNRNGVRLMASPSTCIQFEPGSDDFKVGDQAPGYR
WLRLLPDGELETGVERVTGFDFQVDYGSNGY
>A0A5E6PN38|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADPALLVQISDSHLYAEADGALLGMNTRDSLQKVIELVREQQPRIDLILAT
GDLSQDGTLESYQQFRDMTRQLDAPARWIPGNHDEPQIMAEAAVQSALLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQVRAVLWGHVHQEVDQLRNGVRLIASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGRLETGVERVTGFDFTVDYGSNGY
>A0A5E6S3N8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MMANNKVASLFVGAFLLFSVFMAHAVPDAPKHMVFASDTQYPWTDKTDSRTPESGEEFTK
RSKWLVESQLASIADFRTRNGSQSTIPLMINGDITAFGHGWQRDYMAAALKRHFGTNYLY
GLGNHDYENNVDDCFSNSCAAGSIVQFKEYHEGKVDSFDLTISGSVVNRLYSGSLAYSKT
IGDVHLVQLNNEPTYTTRIAHFLNPTTFEINSALDWLEKDLRLARVQGHAIIINMHKPLE
MKGSPSQQKRFIEMLKTYKVTAVFAGHLHKYGGSSYWLGNVPMYLSGATSQQTYLITSFT
EDRKQLQIYLVKNNQWRNRELIDTVPVQSIWANRP
>A0A1H8UB88|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. NFIX58|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGD
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLTGAQFRPDTASEGY
>A0A8D2HTP5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Urocitellus parryii|TrEMBL
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQ
KDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIF
NVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAAD
VAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDES
VLENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMV
ETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKE
RERGMEISPMCDKHTASVEKSQVFKRRNFLVFVELESSISFFIL
>A0A1X3JSM2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia albertii B156|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYLHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCRWLDQHSL
RNAGELDNVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A6C6ZHH3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella heidelberg (strain SL476)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A7I6TE73|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella sp. WP7-S18-CRE-03|TrEMBL
MESLLNLPLAGGASVRVLQITDTHLFAEKNETLLGVNTWESYHAVLQAIHASARDVDLVV
ATGDLAQDHSAAAYQHFAEGIASFTAPCVWLPGNHDFQPSMYSTLQDAGISPAKRVLVGE
HWQILLLDSQVFGVPHGELSDFQLEWLEKRLAEAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAASLDTVLVRYPRVKHLLCGHIHQELDVEWNGRRIMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHADGSLTTDVCRLAGVKFHPDTASEGY
>B7N0H9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O81 (strain ED1a)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLHHHPLPAGCSWLDQHSLR
NAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAP
GWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A674JKX9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Terrapene carolina triunguis|TrEMBL
YFQNSHFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSM
SRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLPDRAPNKRSPMCNQPSINKA
TITGKRD
>A0A3B7PWD7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. WCHAc010034|TrEMBL
MPLLMNTETPPDWTIVQISDTHLMDQEDLEFAGMNPEQSFHEVMAHITQRLSPIHAIVHT
GDLAQVPVQATYARYLQHMQQQGLPHFQVPGNHDDTALFPFHQQRDQAHVLSFGAWRIVL
LNSAVAGQVDGWVAQQQLQQLEQILAQQADQHVIIACHHHPFAMQSRWIDQHKLKNAEHL
MDVIAKHRNVKAVLCGHVHQDSCHEWHGVQFLSTPSTSVQFKPRSDTFALDQSAPGYRVL
HLRENGEFSTEVVRVKISQPEINLQISGY
>A0A8H9U729|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kluyvera intermedia|TrEMBL
MESLLNLPLAGGARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIQAQQRECDLIV
ATGDLAQDQTAAAYQHFAEGIARFGAPCVWLPGNHDFQPAMYTALQEAGISSSKRVITGD
NWQILLLDSQVFGVPHGELSEFQLDWLEKKLSASPERHTLLLLHHHPLPSGCSWLDQHSL
RNAAELDNVLARFPHVRYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLYPDGSLQTEVCRLQSTRFNPDTASEGY
>A0A240EFQ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio thalassae|TrEMBL
MTPSDESQLSSVRLLQLTDTHLFAPQDGCLLSVNTQESFHAVVAEIVAQGQRFDALLATG
DISQDHTEASYEKFVAGIEPLALPCYWLPGNHDYKPCMNSVVSSPLIEDVTHVLLGDKWQ
VVLLDSQVVGVPHGRLSDAQLEFLDRMLSTYSDRHTLVLLHHHPLLVNSAWLDQHSLKDA
DEFWNVVEKHDNVRAVLCGHIHQELDEMRNGVRVLATPSTCVQFKPNSNEFALDIRSPGW
RELELKQDGSLHTEVKRLTNGSFRPDFNAEGY
>A0A7T6X6N1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ralstonia pickettii|TrEMBL
MPMHFLQLTDLHIKRPGQLAYRRVDSAAYLSRCVAHILAQPEKPDAIVLTGDLVDAGAPE
EYAHLRAVLAPLDAAGIRMLPVLGNHDGRDAAREAFADWLAPIPADAQDTHALQYWTDIG
DVRLIVIDTLDSGHPGGRLGVQCLDWLAEALARETQRPTVIAMHHPPFATGIGHMDVQSL
APEDIPAFAQIVRAAGNVERIICGHLHRSIDVRFAGTVASTCPSPAHQVALDLDPNAAPG
FVMEPPAYKVHAWVPGQGLVSHLAYVGQFDGPHPFFEPDGRLID
>A0A399ER55|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Meiothermus luteus|TrEMBL
MRVFAIADIHLSKAFPKPMNIFGPEWEGHPEAVFREWRRVVGEDDLVIVAGDISWAMKLP
EAMADLEDLAQLPGHKVLLRGNHDYWWPSISRLRQALPPRMYALQHDSLVIGNLAVAGSR
GWDTPGSYNFTPEDEKIYKREVERLSLSLKTLRGQAYEHLVLAMHYPPFGPSGGPTGFTE
LIERYRPSCVVYGHLHGADPEKLPKTWAGIPLHFVSADVVRFQPQLVLETERQTHL
>A0A2M9W7S9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea rodasii|TrEMBL
MDSLLTLPAANGADIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIMAQQHDYDLII
ATGDLAQDHTVEAYQHFVAGITRLPKPCVWLPGNHDFQPAMVDTLADAGVASDKHVLLGE
HWQLVLLDSQVFGVPHGMLSEYQLEWLDKALRKHPERHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLQHFPRARNLVCGHIHQELDLDWHGRRVLASPSTCVQFKPHCTNFTIDNVA
PGWRWLTLKADGVMETEVNRLQSDLFRPDLDSEGY
>A0A6P7FLV7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Diabrotica virgifera virgifera|TrEMBL
MVNNGIIPKVTTKPVGSSILKTREYKRATSEVKLGQITPPSRLLKILTVFSALDQVGETI
VKAAEKLGFEITTSTSDKAALEEYQQRLHDLVIIDSRSPKGINYDTLCRSLRNTKGNQHT
VVVAVVKKSAFEKDDNTIGSLLDSGFNRCMVETTNIVASGNELILLRHSDIRPLAQHATT
QGLYSALDKCKDIVVVTDDKYNLQYINRACEKQLGLRQEEVLGRPLQDQLMFDPAQVNPM
GSSLLRGKDWQGPITLKKKPLETILASCKAVPFACAGRLPTHFILVFDLNPTDQLNMLAQ
SRGSIHSIRRGSTDVRSVGSDFLRRTSLAKLNALPLEAPITKVVGLIDQARENSNQNPSV
VQLLDKVEDILKSCELYSTHVKEDLRIKSDEPVVSDLITALLSKQPQPTLSGSSRRSSND
SSVFRQSRGGLMKVPTVIKELLDHCLSWEFDIFRLEDLTKKRPLQYLGMSLFNHFEVASV
LNCDEKTLFNWLTVIEANYHMENSYHNSTHAADVMQATAGFLEKDRMKSIIEQLDEATTL
IAAAAHDVDHPGKSSAFLSNSDNQLAILYNDVTVLESHHAALTFKLTLGDERINIFKNLD
RETYKIARANVVDMILATEMTKHFEHLAKFVNVFCTKSSSSDLESEVSDFAPLSIPENVT
LVKRMMIKCADVSNPTRPLRLCVEWARRITEEYFHQTDEEKSKGLPVVMPMFDRYTCSIP
KSQIGFVDYIINDMFEAWNAFIDMPELLAHMRQNYIRWKELDEQGHTTLSDIQKLQATAL
MNPMFPQKPTKGE
>A0A8C9F4H7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pavo cristatus|TrEMBL
MPEANALLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQ
KDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVKTEKEDHLAKELEDLNKWGLNIF
NVARYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAAD
VAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDES
VLENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMV
ETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKE
RERGMEISPMCDKHTASVEKSQVIGLEPRVSIASARVLKAETTLICFL
>A0A8C9L614|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pavo cristatus|TrEMBL
KFKGIRQECFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSP
KSMSRNSSIASDILKPFCLFQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKAT
ITGKRN
>A0A093IFN3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Eurypyga helias|TrEMBL
FDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSS
LPSEQHGDDLIVTPFAQVLASLRSVRNNFTLL
>A0A644UPU1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MRILQLSDTHLRGDHSLSFRVVDTRRCLDEAVAHVKSLTQQPDIIVITGDLADSGDLNAY
HILHDELSPLGVPVYAVPGNHDRRDRLREVMPHWCPAKEDIAPYLCYTVEEENLRLIMMD
SMSPGSHSGHFPAETGDWLERELAKRPDTPTMFFMHHPPFVTGMGAMDEPFENMERFAAI
VERNPQMRLCFGHMHRPIVTEWHGRIAMTAPAVSMQIDLDLSPEGGDTFRMETPGYLLHH
FDKGVWNSHICQIAVQATFAGPYPFAGSVNPTQ
>A0A644V0K6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MYMKKTTLFLLGILFSLGISAQTPFYFIQLTDPQFGMIDKNASFDKETALMEKAVKQINK
LNPGFVVVTGDLVNDGNNADQIKEFKRILATLRKDIPVYLTPGNHDVGQQPTSASLAGYI
DTYGYDCFSFQMNGTCFIGINTQIIWADVKDAEQSQLVWLTKVLENSQKCTHRILFGHHP
VFVHSADEADKYDNFPLAKRNDYLNLFNRFNVSDQFAGHLHYNSSGQYGNFRITGTSTVG
MQIGKEKSGLRIVKVYPDKIESTYYPLDEVPAIVEL
>A0A839I0X2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aliivibrio sp. SR45-2|TrEMBL
MLSETLLNKKNGPIRLLQITDTHLFALPEGALLGVPTLKSFQSVVEQVQQQSPHFDAILA
TGDISQDHTVQSYQHFVEGIEPLKKPCYWLPGNHDYKPSMGGVLPSPQIKDCEHLLIGEH
WQVVILDSQVVGVPHGALSTEQLQLLDSALSQHSERHSLILLHHHPLPAGSAWLDQHQLK
DNEVFWEVLAKHRNVSGILCGHIHQEMDCIVNNIRLMATPSTCVQFLPDSNDFALDSKAP
GWRTLDLLPNGEIVTQVYRLEHCDFSADADAGGY
>A0A329W270|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus sp. S9-53|TrEMBL
MESQFELPVVEGTTAKILQITDTHLFASKEDTLLGINTYRSYQAVLDAILKQNADIGLIV
ATGDLVQDQSLEAYRHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGK
HWQLLMLDSQVQGVPHGELSEYQLEWMKKCLDRYPERYAVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQGYSRVKAMLCGHIHQEMDLDWNGIRMMATPSTCLQFKPHCTNFMLDTVA
PGWRYLELSVADNGEFGLTTQVYRLASNEFCPDLDSDGY
>A0A369ZNI2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus paraphrohaemolyticus|TrEMBL
MNTFYPLEPKKSVIKLLQITDPHLFSDTTKDLLGVNTYASFQAVLDEIQAEIQTQAVDFD
AILATGDLIQDHEFEGYLHFAEMIQPLAKPLFWLEGNHDQQPQMSLQLGKFDYIRPEKQI
FAGEHWQILMLNSQVASAPNGFLSKGQLAWLNQKLSENPERFTLVVLHHNILFTNSAWLD
QHSLKNSDTLAEILALYPNVKAILHGHIHQEVDAIWNGIRILSTPSTCIQFKPNCDDFTL
DNLPQGWRELSLFEDGHIETEVKRLKTQAFLPNFDSRGY
>A0A3N9THP8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio viridaestus|TrEMBL
MSDNNISIDVENDNCVKLLQITDTHLFVDDDGSLLGVNTTESFTAVVDAIIQGVTDFDAI
LATGDISQDHTPESYHKFIQGISPLKKPCFWLPGNHDYRPNMASVLPVPQVKCIPHFMLG
SHWQVVLLDSQVEGVPHGYLSAQQLSLLEEKLTAYPDKHTLILLHHHPVLVESAWLDQHT
LKESESLWDVISRFDNVKAIVCGHVHQDMDILKQGVRVIATPSTCVQFKPRSNEFALDLL
SPGWRELNLLEDGSVETKIGRLDNGRFLPDFYAGGY
>B3MFI3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila ananassae|TrEMBL
MGCSPSTLPAPSSTSAAAGGQPTSGQGSLPPLDASEKDGSRLFCIKLRRSRLRRCSCGGV
TPQTPNDGNGSTAGSGAGDNLCGQVLLNPLQTKNEADYEKLSTGKKDSIVTVAALGNFTH
SVVRRATGSTGTSGTSSSGGGNSRPGHRKSSLAFALTPEDEPMDVYQRNLMDLKYPTVLP
PNPQLKALLVFYKADSICEAVSAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIII
DARSSKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTN
LAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLN
MRLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMHVRVVPVACIGS
APTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLT
SLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDL
IGALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKANPIIMELLDESLSWDFDIFK
LEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADV
MQATGAFITQLTNRDMMVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDL
TVLENHHAAITFKLTLGDDKINIFKNLDKEQYKSARSTIIDMILATEMTRHFEHLAKFVS
VFGGEETREPHAQSEEETSILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYFMQTDEE
KQRHMPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKK
YDEQGINTLADIMAKQPPVGKLANSKXHTAFRRLFSGLLKPLPAHAPATSTIGENEMEDV
L
>A0A2T9QBA4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Cerro|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A2R4USV1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter junii|TrEMBL
MTFQVSTLSQKDFVMIQITDTHLLEYPHLEFVGMQPEQSFHAVIDLMRQTHPEIDLIVHT
GDLAQNPTPLTYHRYLEYMHSLSIPFFQTPGNHDDVNHFPFHEQDKTAPTVVELGNWCVI
LLNSAQPNRIDGKIADAQLQQLPKLLTQLHDRYVMIACHHHPFAMQSAWIDQHKLKNSSD
LLETIQPFSNVKAIICGHVHQDSITSWQGIEFLSTPSTCIQFKPKSEKFALDEEHPGYRY
IRLKANGEIETQVHRLSNSQRLSSSEVLGYD
>A0A318P328|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia plymuthica|TrEMBL
MESLFKLTVASGARVRILQITDTHLFAGENETLLGINTYRSYHAVLDAIMAQQRDFDLVV
ATGDLAQDHSLAAYRHFAEGIARLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLLGE
NWQVLLLDSQVFGVPHGELSDYQLEWMERCLQAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAVLLRYPNVNTVVCGHIHQDLDLEWQGRRLLASPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSEGY
>A0A0I2UGK2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella sonnei|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A5W1EUU3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. arizonae serovar 18:z4,z23:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYGALQEAGISPAKHVLIGE
EWQILLLDSQVFGVPHGELSEFQLEWLERKLANAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSLLAHFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A1J0J143|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas aeruginosa|TrEMBL
MSRHSNTPATDASVLLVQLSDSHLFAEDGARLLGMDTAHSLEKVVERVAREQPRIDLILA
TGDVSQDGSLDSYTRFRRLSAPLDAPLRWFAGNHDEREPMQRATEGSDLLEQVVDVGNWR
VVLLDSSIPGAVPGYLEDDQLDLLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGY
RWLRLHDDGRLETGISRVDDVVFEVDYDTAGY
>A0A1E3XMB3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurella multocida|TrEMBL
MFSTYRYDTSAEVFKIIQITDPHLFKDEHGELLGINTFQSFSQVLHEIKASRFDYDLVLA
TGDLVQDSSREGYLHFCEQVKSLEKTVFWIPGNHDFQPKMFEILNQDQGNLNPKKHILLG
KSWQILMLDSQVFGVPHGELSQYQIDWLVAKLKDHPERYTLIVLHHHILPTHSTWLDQHN
LRNAHELAYALAPFDKVKGILHGHIHQEMDANWQGYRVMATPATCIQFKPDHNTFTLDSV
QPGWRELELHSDGRIETRVKRIQDKTFFPNMHEDGY
>A0A5I6L169|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Coeln|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5I1UXH0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Durham|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A087FVH8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella variicola|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQASGISPAKRVFLGD
HWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDRALSAWPRVRHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAEFHPDIASEGY
>A0A0Q0YX10|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio metoecus|TrEMBL
MKVSSQSEDSSVKLVQITDTHLFAAENGSLLSVNTADSFAAVVAAIGEEKVVFDAILATG
DISQDHTAESYQRFVSGIQPLQKNCYWLPGNHDYKPSMQSVLPTDQVQAQEQVLLGEHWQ
MVLLDSQVTGVPHGKLSEQQLQLLDNKLTEYPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHRNVKAIVCGHVHQDMDRLHLGARVMATPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A6J5EZB2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Burkholderia paludis|TrEMBL
MKVRVLSDLHLEGNQPDTIPHADADLVVLAGDIHNHAEGLRWAAETFDPAVPVIYVPGNH
EYYDGEFGALETAMRDAAHTLDNVHYLNNDVYVDPERRFRVLGTTLWSDFSLFGDDDASM
AGSIAAALRVMLDFKGLIQVTWPQDAALHAAPGGPERDFAPADAIALHRQGRAWLEAQLA
TPFEGRTIVVTHHAPHRRSLAERYADDPASAGFITDLAELVRPPVDLWLHGHTHTSFDYI
AEGGTRVVCNPRGYIHRRTGERENGAFAWDKVVELG
>A0A2I5HLA6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella diarizonae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLVLQANGVLETEVHRLQDTRFRPDTASEGY
>A0A380UA15|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter johnsonii|TrEMBL
MTLNNEKNWTIIQISDTHLMDQDHLEFVRMNPEQSFHHVIQHIVERHPQIDAFVHTGDLA
QVPVPRTYQRYLDFMQSLKTPFYQVPGNHDNAEHFPFHQQQNKVHVIHFGPWSMVLLNSA
VKGKIDGWVDEAQLNQLEQILQEFAQQHIVIACHHHPFEMQSKWIDQHKLKNTQDLTAVL
AKYHNVKIVLSGHVHQESWREWHSIQFYSTPSTSVQFKPLSDHFALDEQAPGYRILQLNA
DGSHETHVERVLHAQQKINVEISGY
>A0A0L8DRF9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio parahaemolyticus|TrEMBL
MQSSNDSIKLLQITDTHLFAADEGSLLSVKTADSFSAVVNEVLRRKVGFDYILATGDISQ
DHSAESYQRFADGIAPLQKDCYWLPGNHDYKPNMGSVLPSPQIQAAEHVLLGEKWQLILL
DSQVVGVPHGRLSDQQLTLLEEKLTEFPERHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFDNVKGILCGHVHQDMNVIHKGIRVMATPSTCVQFKPNSDDFALDTTSPGWRELE
LHTNGDITTHVDRLPEGQFQPDFSSNGY
>A0A191W693|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio anguillarum|TrEMBL
MNVSPTLDNSDSIKLLQITDTHLFAPDDGSLLSVNTVDSFHAVVAEICAQHAEFDAILAT
GDISQDHSAESYLRFSRGISSLEKTCFWLPGNHDFKPNMGAVFPSEQIQQSEHVLLGEHW
QMVMLDSQVVGVPHGRLSDQQLALLDEKLSTHHQRHTLIVLHHHPLLVGSAWLDQHSLKD
SDAFWNIVTQHRNVKAVLCGHVHQNMDKLHHGVRVMATPSTCVQFKPNSDDFALDRTSPG
WRELTLSADGQIETQVKRLANGAFQPDFNANGY
>A0A6J3KGV5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bombus vosnesenskii|TrEMBL
MGCKTSMLECIEDTGEAEKRKHSDMVNQGSLLGKTEYDVLRRRSSFEDVAVDDDENADCS
ALKGPQNIEAHPLTNSVPSLIKILLVFPKDDQQMDVLATTSRRLGWSVSVAKDAEKAVEF
FQNRGHELVIIDHRGQRAAEADTICRYGELFFKNQPNSSGVRLYILINTIYFRAIRSSPA
YHNSIIIALVKKSFLMHGEKDKIVTLDLLETGFSRALMECSHERLLINELVGIYASALLP
RTQLAAANALYVALDRCRDMVHVTNDKHIVQFVNKISEKLLGYKTSEILGKSIADIVVYD
NFVLMEQHISKGREFEGNMNCKRKNNQMITISCRVIPFSINLKKPTHYIYIYDTTYLSEN
IGSLSPTPSQSVYSRGNMIVSQRRTSDMKSSEGRRRSSAHKLHSLQLDAPITKVISLLSN
AITESTTPDTAAQIEKAIDILKTTELYVPSLREDTDPVTTDLVGALLASPRKAWESRRSS
VESTRVSMSKTFSTTTASRMQIKSFRGPQEIAEILERCLEWNFDIFKLEILTEKRPLLFL
GTTIMNMYRVPARLGCEEKVVQNWLTVIEMNYQSRNSYHNSTHAADVLQATARFMQSERL
QQILEPLDEVATLVAAAAHDVDHPGRSSQFLCNSDNKLAILYNDLSVLESHHAALTFKLS
LSDDNVNIFKNLERDTYKQLRQTVIDMILATEMTKHFEHLAKFMNICSARMMDSPQLDDY
TDTVDMSVVLQPENVVLVKRMMIKCADVSNPTRPLKCCVEWARRIAEEYFNQTDEEKRMQ
LPVLMPMFDRATCSIPKAQIGFVDFIINDMVEAWDAFIDMPEMVGYMRQNYEKWKEYNDR
GISTLPDIEKIQELPELRIYQLPS
>A0A3Q1EXV5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acanthochromis polyacanthus|TrEMBL
SAGLYPLLPGYHGCFYWQKEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKVRT
SKKFFLQLTPCTAVPVLHVKAAQGFSCFFIPQ
>A0A753B5R7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. houtenae serovar 45:g,z51:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A0W8AWK8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pneumoniae|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A3V9S3L4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Kentucky|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A155NHU6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter hormaechei|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEKRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQEAGISPAKCVFTGD
QWQILLLDSQVFGVPHGELSDYQLDWLETKLAAEPNRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLAKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIG
PGWRWLDLHADGSLTTEVCRLAGAQFRPDTASEGY
>A0A659NF44|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Wilhelmsburg|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A1B8SYJ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia rettgeri|TrEMBL
MDSQLEVTAKNSKIVRILQVTDTHLFANTENTLLGVNTYRSYQAVLDAITEQNLPIDLIV
ATGDLVQDQSPQAYQHFADGIARIPAPCVWLPGNHDYPPAMVETLRVAGISSAKQILIGD
EWQILMLDSQLQDVPHGELSEQQLEWMKASLDAEPERTTLIMLHHHPLASGCTWLDQHSL
RNSHILADYLKNYPNVKAMLCGHIHQEMDENWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELSINEQSQRHITTHVHRLDTREFSPDLDSDGY
>A0A8E3MC22|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mergibacter septicus|TrEMBL
MSGIYQHTSVSDVVKVLQLTDPHLFADSKGELLGVNTLESFKQVVREVIKSNFAYELILA
TGDFVQDDSREAYQHFVQQVSPLIQQTDLKPLFWLPGNHDFQPNLLEVFQYSKEIYPEKH
LLLGEYWQVLLLDSQVAGAVYGKLSQEQLQWLDQQLALYPQRHALIAFHHHLVPTNSAWL
DQHNLRNSYQLLEILQRHQQVKVLMYGHIHQAVDTNWYGYRVLATPSTGIQFKPDCAQFT
LDNLQPGWREISLYPNGEIVTTVKRIEEKLFLPNVNVSGY
>A0A0P8JAI4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter kobei|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAEHRDCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
KWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLTKFPRVKHLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLAGAQFRPDTASEGY
>A0A1Y6GFL7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Raoultella ornithinolytica|TrEMBL
MESLLNLPLAGETRVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRPCDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEQKLAEEPERYTLLLLHHHPLPSGCSWLDQHSL
RNAGALDRALAAFPRVKHLLCGHIHQELDLNWNGRRMMATPSTCVQFKPHCANFTLDTIS
PGWRWLELHADGTLTTEVCRLNGVKFHPDIASEGY
>A0A2T9I899|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Agona|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A0H0YG28|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio alginolyticus|TrEMBL
MQSSSDSIKLLQITDTHLFAADEGSLLSVKTVDSFNAVVADVLRRNVAFDYILATGDISQ
DHSAESYQRFANGIEPLEKDCFWLPGNHDYKPNMGSVLPSPQIKAAEHVLLGEYWQLILL
DSQVVGVPHGRLSDQQLTLLEEKLAEHPERHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVERFDNVKGILCGHVHQDMNVLHKGIRVMATPSTCVQFKPNSDDFALDTTSPGWRELQ
LHACGDITTQVGRLPDGQFQPDFSSNGY
>A0A501Y1E9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. LC6|TrEMBL
MLKEAISYSVADESVRIVQVTDPHLFADPEAQLLGVNTSKSLAAVLNTIRAVNYPAHLML
ATGDLSQDYSPESYRQFVSAVAPLNLPCHYLPGNHDDPRIMFLHMQGERIFGQQRILVGK
WQILMLDSTVRGKPGGHMAASQFELIEQAIAAHPDRHTLLVMHHNPILVNCAWLDQHCMD
NGTEFLKRVAKYPQVKALLWGHVHQQLDSLYDGPHGALQLMATPSTCIQFKPQSPYFALD
GLQPGYRLLELKADGSISTNVYRVPGNLFSPDKDSSGY
>A0A3V7LW26|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enteritidis|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A4U8IXN2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Chester|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A486WYC8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Stanley|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A7W3B0H7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella sp. RHBSTW-00215|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQILLMDSQVFGVPHGELSDFQLEWLEHKLAEVPERYTLLLLHHHPVPSGCGWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHSANFMLDIVS
PGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A5M9IE66|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas panacis|TrEMBL
MRESLLVNRPFLVAQISDLHLKAGQRLTYGVVDTLGALRRAVDHLNASHPRPDIVVISGD
LVDFGRADEYAVLHPELARLHMPCYLVPGNHDTRGPLLEAFRDHAYLPLSAEGPLDWVVD
EHPLRLIGLDSTIPGGHGGQLLDSQLHWLDAQLARRPDAPTLLILHHPPFISGIGHMDRE
PFINAAALEAVVSRHSQVERLLCGHLHRPMQRRFGGSLSCVCPGTSHQIVLDLQDAAPAH
FNLEPAGYLLHRWDAQQGLISHNGVFGDYPGPYPFYDAHGLID
>A0A2D4IAP3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micrurus lemniscatus lemniscatus|TrEMBL
MMKEHCSPYNSAGPSRISNSTMESLPSLKPNYMSVCLFAEESYQKLAMETLEELDWCLDQ
LETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPT
QKDREKKKKQQVMTQISGVKKLMHSSSLNNTSISRFGVKTEKEDNLAKELEDLNKWGLNI
FNVARYSHSRPLTCIMYAIFQERDLLKTFKISSDTFIAYMMTLEDHYHTDVAYHNSLHAA
DVAQSTHVLLSTPALDVSCFPPPLTNNTSKTICLHLVICYSLML
>A0A6S7CPM8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pararobbsia alpina|TrEMBL
MRFAQISDLHITPPGELAYGKVDTAGFLGRAIDRLNALGDSLDAVLITGDLVDGGLPEEY
RHLRTCLDRLQAPCYLMVGNHDDRLALREVFADRAYLHEGGAFVQYGVDIGALRIIALDS
LIEGEDAGTLCDERLAWLDTELAQSRNRPVVVAIHHPPFSTGVGHMDDILLERDASRRLA
DIVRAHPNIERVLSGHLHRPIHARFAGTIASTCPSTAHQVMFDLRADAPIAFIMEPPAYA
LHQWTVDSGLVTHHLYIDSFDGPYPF
>A0A7K7I3L2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rhegmatorhina hoffmannsi|TrEMBL
FDLENGPPGRGTLDPQASPGAGLVLQGTFSHGQRRESFLYRSDSDYDLSPKAMSRNSSIA
SDLHGEDMIVTPFAQVLASLRTVRSNLTHLQDRTGIKQGPLPSWRVPPAEDAHQKLSRET
LEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSETSRSGNQVSEYISSTFLDK
QHEVEIPSALAKDKEKERRKRPMSQISGVRKLTHSSSLATAGIPRFGVRTDHEGLLAKEL
EDTNKWGLNVFKVAEYSGNRPLTVIMYSIFQERDLMKTFRIPVNTFITYMLTLEDHYHTD
VAYHNNLHAADVAQSTHVLLSTPALEAVFTDLEIMAAIFASAIHDVDHPGVSNQFLINTS
>A0A385C869|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter wuhouensis|TrEMBL
MNAEKLQLTEFHKDRVIIQITDTHLMDRPEAEFVGINPEENFHAVMDDIKQQYPHIDAIV
HTGDLAQAAFPETYDRYINYMKAFGVDFYHIPGNHDNLRFFPFHTPEPSPAVISIGQWRI
ILLNSAVSGQTDGHIQDEQLLELKKILAQLQDCFVIIACHHNPFEMKSKWLDQHKLKNVD
ELKAVLEPFQNIKALIHGHVHQESHNEWNRIPFISTPATCVQFKPLSQEFAFDQIAPGYR
CLHLKASGEFETVVHRLKNFKVTINEEISGY
>A0A034T8V8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Edwardsiella piscicida|TrEMBL
MESLFHLAVASGAPVRLLQITDTHLFAGQQETLLGVNTYRSYQAVLAAIRAEAHPFDLIV
ATGDLAQDHSAAAYQHFAAGVAALHRPCLWLPGNHDFQPAMVDTLAQAGVHANKRALLGD
RWQIVLLDSQVVGVPHGELSDYQLEWLEQTLASEPQRHTMLLLHHHPLPSGCTWLDQHSL
RNAHALDEILRRYPQVNTLVCGHIHQELDLDWNGCRLLATPSTCVQFKPLCTNFTIDTIS
PGWRYLTLYPDGRVTTAVHRLASSEFRPDLDADGY
>A0A2D1QLA8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas salmonicida subsp. pectinolytica 34mel|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQVNEHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VMLLDTQVRGKPHGVLGDHQLAALDSALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEVDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRVASQVWRLPVGQFVPDPDATGY
>A0A564MT57|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella huaxiensis|TrEMBL
MESLLNLPLAGEAKVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQILLMDSQVFGVPHGELSDFQLEWLEHKLAEVPERYTLLLLHHHPVPSGCGWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHSANFMLDIVS
PGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A6I9WS73|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pogonomyrmex barbatus|TrEMBL
MGCKISILKCMRGKVEQEESISSGISNSSSNTSDETETNRDQDSLYLAFNKHHFVVEEDD
REVAQCKTDAFDIVAEKNEKTPFEDSCAYDENGDYLTIKGPQDFSNYLLTTNVPSIIKIL
LVFSKDDQQMDILANAARRLGWSVSMAKDAEKAIELFQNRAHELVIIDHREHHAAEGDAI
CRAIRSSPVYHNSVIIALVKKSYFMLDEKDHIVALNLLETGFTRALMECSHEGILINELV
GIYTSSLLPKTQLAAAHALYLALDRCRDMVHITNDKNIVQFLNKVSEKLLGYKTEEMMGR
NLSEIVYYDNFALMEQQLSKGREFEGNMNCKRKNNQMITINCRIIPFCITLKKPSHYIYV
YDTTYLSENSAPISPVGSPLHPPLRPSVMPNTRKSSDVKSGISEGRRRSSLQKLHLEAPI
TKVITLLSNAVTDTTNPETAAQIDKAIDILKTTELYVPHLKEDKAMYSDPVATDLVGALL
ASPRTAWESRRSSSDSARLSTIKAITYPNSHVQKNFLGSQEITEILDKSLDWDFEIFKLE
VLTEKRPLVFLGLTIMNLYQVPTILHCDERTLQNWLAIIEHNYNAENSYHNSTHAADVLQ
ATARFMQSKKLKAILEPLDEVATLVAAAAHDIDHPGRSSQFLCNANNRLAILYNDLSVLE
SHHAALTFKLSLSDDSVNIFKNLERDAYKLLRQNVIDMILATEMTKHFEHLAKFMNVCSA
RIGEETYSDSLDMSVVLQPDNVILIKRMMIKCADVSNPTRPLKCCVEWARRIAEEYFNQT
DEEKKLKMPVIMPMFDRLTCSIPKSQIGFVDYIINDMIEAWDVFIDMPEIVGYMRHNYEK
WKEYNEQGISTLQDVEKLQQQHPEIQIP
>A0A7X5KA44|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus kayaii|TrEMBL
MESQFELPVVEGTTAKILQITDTHLFASKEDTLLGINTYRSYQAVLDAILKQNADIGLIV
ATGDLVQDQSLEAYRHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGK
HWQLLMLDSQVQGVPHGELSEYQLEWMKKCLDRYPERYAVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQSYSRVKAMLCGHIHQEMDLDWNGIRMMATPSTCLQFKPHCTNFMLDTVA
PGWRYLELSVADNGEFGLTTQVYRLASNEFCPDLDSDGY
>A0A7V8N5G1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. BIGb0393|TrEMBL
MDSLLTLPAVDGSGIRILQITDTHLFAGKHQSLLGVNTWSSFAAVLDAIEAQQQHYDLII
ATGDLAQDHTVEAYQHFVAGISRLPKPCVWLPGNHDFQPAMVDTLADAGIKSDKHVLLGE
HWQLVLLDSQVFGVPHGMLSEYQLEWLDTALRKYPERHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLQHFPRARNLVCGHIHQELDLDWHGRRVMASPSTCVQFKPHCTNFTIDTLA
PGWRWFTLQPDGTLETEVNRLQSDMFRPDLDSEGY
>A0A3B5A4E4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Stegastes partitus|TrEMBL
IGRVSDSVECGCDAVWLKQSYVFISSLFSLCSFDVENGLSVGRSPLDSQTSPGSGLVLQA
NFPHSQRRESFLYRSDSDFDLSPKAMSRNSSTASDLHGEDMIVTPFAQVLASLRTVRSNF
AVLTHLQDRRSDSISQPRAGKKNVTLAA
>A0A424W9C4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alcaligenes xylosoxydans xylosoxydans|TrEMBL
MARIHSLTRRDDAPAMLVQLTDSHLFGEPETSMLGVNTDASLRAVLRQIEADGKHPDLLL
ATGDMSQDGEAAAYRRLARVLSEAPALAQACIRCLPGNHDLPAVMRQELPQWSVPVTDVG
AWRVVTLDTTVPGSNAGHLPASQLDLLEAALAEAPGRHTLVAMHHNPMQIDSHWHDSMMI
DNPQALFKLLARWPQVRVLLWGHVHHEFDRRRHNLRLLATPSTCFQFSIRDGKHVVDNMA
PGYRWIKLYQDGSMATGVRRVQDALWHGAMTASDNAQAA
>A0A3B5AC14|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Stegastes partitus|TrEMBL
TNCSISSVENGVSPGHTPLGSQSPSLTLHTSFPQGQRRESFLYRSDSDYDMSPKTVSRNS
SLASEGHTAEDFIVTPFAQVLASLRSVRSNFTILANVSTPTVKATLSDQQYQQLALDTLE
ELDWCLDQLETIQTHRSVSEMASNKFKRMLNRELSHLSEMSRSGNQVSEYISSTFLDKQN
EVEIPSPTLKDKPMSHISGVRKLSHSSSLSSTSMPRFGVNTDHEDELAKELEDLDKWSFN
IFRVAEFSNNRPLSCVMYAIFQERELLKTFRIPVDTFVTYVMTLEDHYHGNVAYHNSLHA
ADVTQSTHVLLSTPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYND
ESVLENHHLAVGFKLLHQENCDIFQNLTKRQRQSLRKLVIDMTDPTDLTCSASCRCYTN
>A0A399LZV0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas monteilii|TrEMBL
MRPDLTRPVHVVQLTDAHLFADPAGSMLGLETRDSLRHVVAQVQREQPLVDLLLCTGDLS
QDASVASYEAFRELTAPFAVPTRWLPGNHDEARVMAEVAPELVQAVTDIGAWRVVMLNTA
VQGATHGFLENDQLAVLDAALRDAGERHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDIV
EAYPQVRALLWGHVHQEWDEVRDGRRLLATPSTCIQFAARSEDFQVSEEHPGYRWLRLHA
DGRLETGVERALDFDVKLDFDSPGY
>A0A1Y1LB63|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photinus pyralis|TrEMBL
MIICTDENGKDNMESLDEQDGKEESNHSVLHRKSSLPLTPEDEPFDVYRSPPEIKYGLLI
PPNHSPLKLLVVCAHPDPVSEALSKAADKLGYDVTTCHSYEEALEEFLSKLHDLIVIDAR
YTSKALDYDTLCRSIRNTRGSQHTAAVALVKRSVFDKDDVTIMSLLDAGFNRCIAETTNI
VHFVNELIQIRHGDIRPLAQTAVNQSLYIALEKCSDIVLITDDSYRLQYVNRSSERFLGY
RYDELLGKSIHEQFIADPLQVTSMTSSLMRAREWQGSLLVRKKSQDTVSCNCKGIPIICA
GRVPTHFVLILDVHGITELTPTSYSLDKPRGSVQSNRRTSMDVRSVSSDYFRRTSLAKLS
ALPLEAPITKVISLLSQAQEQTNPNVVSIIDKVIEILNNTELYSPHLKDDLRLKCDEPVT
SDLITALLMQQPQIQLAPSSRRSSNDSTAVRNVSRGISKVRVPAQIKDLLDTSLTWEFDI
FRLEELTNKKPLIHLGMNLFLHFDVPATLNCDEKTLQNWLTVIEMNYHVDNFYHNSTHAA
DVMQATAGFLEKDRLKAIMDPLDEASSLIAACSHDVDHPGKSSAFLSNCDNPLAILYNDV
TVLENHHAALTFKLTLGDDRINIFKHLDRETYKVARHNVIDMILATEMTKHFEHLAKFVN
VFCQKTSRVDGESSDYIPITLPDNITLVKRMMIKCADVSNPTRPLRLCVEWARRIAEEYF
AQTDEEKSKGLPVVMPMFDRITCSIPKSQIGFVDYIVHDMFEAWDAFIDMPELVTYMRQN
YIRWKEFDEEGHNTSSDIRKLQNTILMAPAIIPKSSIKRND
>A0A3P8WKY9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cynoglossus semilaevis|TrEMBL
PYLFASLVQVVYRPTLEKQKEECHLFGVLNFEVDNGLLMCCSPLDPHLSSGSGLVPHPNL
TCHGQRRESFLYRSDSEYELSPKSLSRNSSITGDLHGEDFIVTPFAQVLASLRTVRNNVT
ILTNVQLTTNR
>A0A446CNJ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter agilis|TrEMBL
MARIHSLTRRDDAPAMLVQVTDSHLFGEAGTAMLGVDTDASLRAVLRQIEADGRHPDLLL
ATGDLSQDGEAASYQRFASILSEAPALDRACVRCLPGNHDLPAVMRQELAQWSAPVTDVG
AWRVVTLDTTVPGSNAGHLPASQLDMLEAALAEAPGRHTLVAMHHNPMQIDSHWHDTMMI
DNPQALFKLLAHWPQARVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNMA
PGYRWLKLYQDGSMATGVRRVQDALWQPTLAAADKARAA
>A0A1W4UNC3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila ficusphila|TrEMBL
MGCSPSTLPAPSASASAAGGQSAERGSLPLDASEKDESRLFCIKLRRSRLRRCSCGGVTL
QPPSDGNGSTTGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHSVVRRA
TGSTGTSGTSSSGGGNSRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLK
ALLVFHKSDSICEAVTAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSTK
NLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSV
ELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEI
ISKQLEDIFVSDLSTISEQCKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLI
FNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEA
PITKENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRR
SSNDSIIRTGSSTRTASIVPAKMKSNPIIMELLDESLSWDFDIFKLEEITDYHPLLYLGM
EMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKD
MMMMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLT
LGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPRDHNSQTD
EETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRA
TCSIPKSQIGFIEYIIQDMIHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLAEIMAK
QPPVGKMANSK
>A0A5H9YLY2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Kisarawe|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2V3Q4A3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. PNA 03-3|TrEMBL
MDSLLTLPATTESEVRILQVTDTHLFAGKHESLLGVNTWASYDAVLDAIIAQQRDYDLIV
ATGDLSQDHSVEAYQHFVEGISRLPKPCVWLPGNHDFQPAMVDTLAEAGINAHKHVLLGD
HWQVVLLDSQVFGVPHGMLSDYQLEWLNTTLARYPQRHTLVLLHHHPLASGCTWLDQHSL
RNPHQLDAVLQHYPLAKTLVCGHIHQEMDVPWQGRRVLATPSTCVQFKPHCTSFTIDTVA
PGWRWFTLHNDGQLETEVNRLTTQAFRPDLDAEGY
>A0A4U1Z3S0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio kanaloae|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLERKLSEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVSTQVRRLPHGQFLPDFDAAGY
>A0A0T7ENS3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio coralliirubri|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTELPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPHGQFLPDFKAAGY
>A0A6P8Y2C6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila albomicans|TrEMBL
MRNCLPKIASVFRIKSSSAAAHSNESDEDSDTDRYIRAKPTATTTTTTTATAAATTTTST
TITSAVTTESDQLLDNGNKKPQQQQQQQQRSAAKATTTTTTKTADDVDKNRLISDVSTAN
TNSNGWDLEQSHKESNASITNGSIRQRQRQWQQQQQQQVYDKNLDTEMKVPGVEISLATP
VPAMPMPSHGRLSNSSKTPEQMELEYEANVAAERGDIMTPLPRDPRPQGMTFPGDAAAGV
GMGNSSVGGGRNMQPEIVEAIRNLDAQALRLNNLTLEDRCQLTTQQENKPDDDTDYVVLR
RPQKHHPFDRQCHSLYERRLYKGPKLHLWVGNGKKPSPSDDDDLKTFQRNLMDLKYPTVL
PPNPQLKALLVFHKSDSICEVVTLACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLII
IDARSTKGLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDALIALLDAGVNRCIAETT
NLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLL
NMRLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMHVRVVPVACIG
SAPTHLIFNFDIPGGGMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKL
TSLPLEAPITKENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGP
SVYSSRRSSNDSIIRTGNSTRTAIVPAKMKANPIVMELLEESLSWDFDIFKLEEITDYHP
LLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADVMQATGAFIT
QLTNREMVMDRMDEATALIAAAAHDVDHPGRSSAFLSNSNNPLAILYNDLTVLENHHAAI
TFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGSEVEPRE
LVQSEEETSILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYFMQTDEEKQRHLPIVMP
MFDRATCSIPKSQIGFIEYIIQDMMHAWDSFIDMPQLITCMQINYSQWKKYDEQGVNTLA
DIMAKQPPVGNKPSNSK
>A0A5J4RFA8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MPLSTLMGRTLFIVSAVIVVSSFFLSVLIGNHLPSSVTSIMYRVGTSWFFIFVYLLILFL
LLDLLRLTHLLPIHRFMYGSWIGFGVLAGFLTVVMSLGYFNYIRKEKVELSLEINKDVAV
SSLKIAAISDLHLGYGIHRKEFEQWVQLINKENPDIVLIAGDVIDNHPRLLYEQNMAQTF
KRFKAKYGVYAVLGNHEYISGASKSIDFLKEAGVIVLRDSIACIDDTFYIIGRDDRTNTA
RKSIEELTDTLDESKPLIMLDHQPYHLEEVEKNNIDLQLSGHTHHGQILPISWITNRMYE
KSHGYLKKGNSHIYVSSGIGIWGGKFRIGTQSEYIVINLNIKQNH
>A0A5J4Q8T9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
THYGQIFPISLITEMMYEKAHGYLKKGDSHIYVSSGLGLWGGKFRIGTRSEYVVIHLTPL
KTL
>D8E4R6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli MS 119-7|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A6B3LHQ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cholerae|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFAAEDGSLLSVNTADSFAAVVAAIGEELVEFDAILATG
DISQDHTPESYQRFVRGIQPLQKACYWLPGNHDYKPSMHSVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEYPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRIHLGARVMATPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A0E1CCZ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pneumoniae 30660/NJST258_1|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>W5J8B3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles darlingi|TrEMBL
MKAFFRKNKSKSMESLYKPPLAKCDVLTVKQLHTFPQTSEQTPRTHRRYSLFGTRSTSNT
TPSTEETPSTEPSSTGSKDKSPSVGQAIATWDFDAPVNLVTLLTPPADDENVFEETDEPH
KLVNGRGSSLPIATAHHHHHQHHHQRPMNLSPDWMPQDRDDATVEGGEHRLHSPTSPTSS
SASPHVFWPRAYGRRSHHSWRPATAFEEILEEPRDESPTRLVSDLKFPNLLPPNPAIKIL
IAFCKNDPVFEALVNASHRLSFEPTFVKSAEAAIDAFQNPTAGGHHIIIVDARYPRIIEA
EALGRSIRNSKGSQHTTMVAVVKKSVFEKDDTAVISLLDVGYNRCIIESPHVSICSSELR
QIQHSLVRPQNVISTQQALYTALHRSREAVIITDDTLRAQYANRASERVLNMKLDEIVGR
SLGDLVTADISNILSHTSRYKDYDGYLTTRRKSQESSQIHVRAVPVSCIGRNPTHLVLIL
ESSASALASISAAGEALQTLPQGKEVARGSLHSIRRPSFDVRSIASDGLRRTSLVKLSSL
PLEAPITKVLSLLAQVQENCSLEEAKLLDRVMEFLKREGLYSPQMKEIRPEDPVATDLIG
ALLTQGPTNILSSRRSSNDSIIRGGGRPSTGSIVFNKTKESSQLSDLLHTALDWDFEIFK
LEELTDKRPLVCLGLELFRRFDVYNTFNCDEMTFKLWLIEMEKNYHSENTYHNSTHAADV
MQATAVYLQQLSNRELKIMDRMDEATALIAAATHDIDHPGRSSAFLCNSDDMLAVLYNDI
CVLESHHAATTFRLTLADDKINIFKHLDRDSYKLARSIIVDMILATEMTRHFEHLAKFVS
VFGTDVESKEPLPPDNDDNQILVRRMLIKCADVSNPTRPLRFCVEWARRIAEEYFMQTDE
EKRKALPIVMPMFDRTTCSISKSQIGFIEYIIHDMMDAWNSFIEMPEIVRYMEFNYSQWK
LFEEQGINTLSDIKRKQLSLAEEPSSIISLEEKF
>D2A7L9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella flexneri serotype X (strain 2002017)|TrEMBL
MESLLTLPLAGEARGRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A3Q9D4W4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas poae|TrEMBL
MPSVSTVTPDAPALLVQLSDSHLFAEADGTLLSMNTRASLQRVIDLVRAAAADRLNAGHG
DLSQDGTLESYQQFRDMTQQMGVPARWIPGNHDEPQVMALAAVHSDFLESVVDIGNWRIT
LLDSSVPGSVPGYLQDQQLQLLAQALSEAPSRHHLVCFHHHPVPIGCAWMEPIGLRNPEA
LFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYRW
LRLHADGRLGVERVQGFAFTVDYGSNGY
>A0A7Y7RGU1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. B6002|TrEMBL
MPSVSTVSPDASPLLVQLSDSHLFAEADGTLLGMNTRESLQRVIDLVRGQQPQIDLMLAT
GDLSQDGTLESYQQFREMTRAINAPARWIPGNHDEPQIMAHAAVHSDLLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPNRHHLVCFHHHPVPIGSAWMEPIGLRNPD
ALFAVLDRFPQVKAVLWGHVHQEVDRQRNGVRLLASPSTCIQFAPGSEDFNVSEQAPGYR
WLRLHPDGRLDTGVERVQGFAFTVDYGSNGY
>A0A2C9NVG0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Macclesfield str. S-1643|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVRRLQDTRFRPDTASEGY
>A0A385ZL75|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces griseorubiginosus|TrEMBL
MNAPLNTPRMGIPARLADTLSMPERHEYLRRSLSRRGLLAATAVAGATGLAASGTARAAG
PDLVTRSATEHVDGALVAPFGRHLAYGADPRTQMRVSWQVPLPVRDPFLRIGLSPLDLGH
KVPAEVRDLFTPAGVGKSADIDQYYVHAALDNLRPGTTYYYGVGHRGFDPAHPGAAHTVY
SFTTAPDAHSRRPFTFTAFGDQNPSYTSIGLNALVQAQNPAFHLHAGDICYAEETGHGLP
ADSSNYDARQWDQFLAQIEPTSSRVPWMVAFGNHDMEAWYSPNGYGGNEARFTLPGTGFD
PEKAPGVYSFVHGNVAVVSVDANDVSYEIPANRGYTDGRQTAWLDRRLGQLRKTPGVDFV
VVFHHHCAYSTTSSHASEGGVREQWVPLYEKHQVDLVVNGHNHVYERTDPVVQDKAMREL
PIGGTHEPTRGGVVYVTAGAGGESVYSFPVADSYEGHEDEVGAVPTYFTGAGGKVTESVD
WSRVRYTGYSFIRVDAKPAPAGRTATLTVRALAATGAEVDRFVVARKAG
>A5UGR5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae (strain PittGG)|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYTRFVEMMRPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGKH
WQAVLLDSQVYGVPHGQLSQHQLDLLKETLGKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTQVKRIQQAEFLPNMQEEGY
>A0A525CN68|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MDSLVVSEDKTSIRVIQITDPHLPEHDGDTLAGADTLNTFLSTVEKIKECSLPADLIIAT
GDIVQNATSPHGYETFREIIEPLGIKTLVIPGNHDQADILTNTLSDGLVSYSQHFIHNNW
QFIMLDSSIPHAVNGHLKTEDLDEVDRLLTENPDHHTLIAMHHQPMPIGCRWLDICDNGA
IDNGNELFGIVEKHANAKVVMWGHIHQDFISSRNNVHLVGAPSTCIQFKPRHIDFCLDRL
PPGYRWLELEDDGSIATGVIRTNEIPAEIDFNTNGYE
>A0A4Q5Q3R0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MAKTVVSTKRFIQISDCHLGPLTSEALLGLNTDESLHDVLALIAEKESDFDYMVCTGDIA
SAGHESCYRRFIDIVRQYFSQSLAWLPGNHDSSEIMAKINLPELPENRAIEQGNWLILLL
DSVVPFKVHGNFEQGELDYLEHMLSTNPDKHIMVMLHHQPVLVGSAWIDQYILRNADAFF
AVLDRFPNVKTVVWGHVHQDFNDTRKGVALIATPSTCVQFKPKYDDFTVDTLMPGYRWFD
LNDDGSFSTGVERVTGKQYVIDYKSAGY
>A0A7C0VTE8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MFARQKAGRFPSPAHGDPVPLHWGAVRDRAGWPSGPPAGSLRVLQVTDTHLYRDADRTLL
GINTQRSLEQVLEQARYEHGPADLVLATGDLVHDHAREGYARLRALLHSLGAPGYWLPGN
HDDPQVMREVLAGAGACDPRSVRVGRWQIVLLDSRIAGGGDAGRVSHAGLRSLDEDLGRY
PDHHALVCLHHPPVPIGSRWMDAIGLQNAAELFAVLDRHPQVRAVLCGHIHQEFETRRAG
VRILGSPSTCFQFRRRSDEFALDSAAPGYRWLALHADGGIDTGVGYLEDFTAAVDMASTG
Y
>A0A3R9QDE5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter lactucae|TrEMBL
MTFQVSTLSQKDHVIIQITDTHLLEYPHLEFVGMNPEESFHAIIQQIRNKHPEIDAIVHT
GDLAQAPMPITYKRYIQYMQTLGLPFFQTLGNHDNVDHFPLHKENHQEPVVIGLGNWRVI
LLNSAVKGHIDGHLSEEQLEKLTALLEEFADNPILLACHHHPFAMKSKWIDHHKLQNSNA
LLNTLAPFKNVKALVCGHVHQDSINIWQGVEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLKNDGSFETEVFRLENFQGHINTDISGY
>A0A6J5DZH6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia humisilvae|TrEMBL
MSSTLGHLKRRDFLKLAAVGGAAFASALPGFTYGRDQDFYFVQLSDAHWGFEGPAVNPDA
KGTLPKAIAAVNALPAKPDFVIFTGDLTHTTDDPMLRRERMKQFAAIVGALNVKPLYLMP
GEHDASLDAGAAYKENFGPTHYTFDHKGVHFITLDNVSDPAGRVGAEQIAWLAADIDKQP
QDARIVVFTHRPLFDLAPQWDWATRDGAQVIDVLTRRQNVTVFYGHIHQEHHTMTGNIAH
HAARSLMFPLPAPGSQEKRLPVPWDAAAPYRGLGWRQVDVNTQPRSFALNEMPIRNIS
>A0A673MW23|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sinocyclocheilus rhinocerous|TrEMBL
MDRTYPVDTGNRPGLKKSRMSWPSSFQGLKRFDVDNGTSSGRSPLDPMASPGSGLILQAN
LVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFA
ALTNVQQERPNNKRSPMCNPPPITKTSYTGVVSLLSIF
>A0A5E4W6C9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea eparura|TrEMBL
MRLHILSDLHLSVAPLAIPEVDADVTILAGDISRPAQAIEWAKALGRPVIYVPGNHEFYG
ATLAGTLADLRHLSAGTDVHLLERGSVIIGGVRFVGTTLWTDFALYDADGKHDDALEESR
KFVRDFTRIRVGDPAVPWPDLPFFSPDDCAALCRENVAWLARVLAAPHDGPTVVVTHHAP
TPQSIHPRFAGSLVNPAFISDLTSFVEASEAALWIHGHTHDSFDYRVGPTRVLCNPRGYC
FEGRVENAAFDPTLTVRV
>A0A2J8NHG0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pan troglodytes|TrEMBL
HGDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQGRPCHKVY
LDVSR
>A0A7J0AYB2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alistipes sp|TrEMBL
MKRLLIINIFILSTLSAAFAAPPRNGAVKGRVAAGGRPMEGVVVSDGDNFAVTDSKGVFS
LESSEEAPFVFIVTPSGYVAESEDGFPRFYLPRDGRRSYDFELKAFGSPDGGFELLAIGD
PQPQTEEHMSRLQSEIMPALTQIVEECRQRNALPEAAILLGDIVWDRMYLMPRVREIFST
LGIPVYPVIGNHDHDLACDNDFDATHAYRENFGPAYYAFDMGGTHFIVLDDIEYYGKKEY
DERVSDRQLAWVEKYTAYLPEGERVCVAMHAPAMKYWRDRWQMSSNRRLMKLLSKYELHF
LTGHSHINSNYDITPGVVEHNVGQVNGNLWHAPLNSDGSTKGLSIITESDGRWSWLYRTL
GQGEDYQMRIWLPGELKEHKPFVVAKIWGWDPCWTVVWYEDGRYRGAMERLTMTDPDYMA
FVDTVRVEPRIRRNLLKSIRNAEFYFRALPSADAREVRIVATDRDGRQWSQTVTVR
>D4ZFI7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella violacea (strain JCM 10179 / CIP 106290 / LMG 19151 / DSS12)|TrEMBL
MLKEAISYSLEEKASVRIVQVTDPHLFADPSSQLLGVNTAKSLESVLNAIKTGDFPADLM
LATGDISQDYSGESYHSFVRSIAPLDLPCHYLPGNHDDPRVMSLHMQGAKIFGQRRILAG
NWQIIMLDSTVRGKPGGHMSDSEIEIIKSAVADQPERHVLLVMHHNPILVKCRWLDQHCM
DNGSDFIEQVAQIPQVKGLLWGHVHQELDEEHQGMHGIIHLMSTPSTCIQFKPLSSYFAL
DALQPGYRQLELKSDGSMITNVHRVLGDKFFPDRNARGY
>A0A4P7TIK3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella flexneri serotype 5a (strain M90T)|TrEMBL
MESLLTLPLAGEARGRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A2S0Q863|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nodularia spumigena UHCC 0039|TrEMBL
MHWLLSGPLSIERLTVKIAGLPASLEGKKLVQMSDFHYDGLRLSEEMLEQAIAISNQLKP
DLVLLTGDYVTTSTEPIHDLASRLKQLKSQAGIYAILGNHDIYYKHSKSEITNALTSIDI
NVLWNEIAYPLGEDLPLVGLADRYSPEFNPTVVMNQLNPDIPRIVLSHNPDTAELLQGWR
VDLQLSGHTHGGQIVIPGLGPILVGYKKILQNVPQKVRYRFPCLRKNYLIIRHWEWSQGL
HQVGNNQLYVNRGLGTYFPGRLFCPPEVTEIILQKA
>A0A329VXV0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus sp. S10-54|TrEMBL
MESQFELPVVEGTTAKILQITDTHLFASKEDTLLGINTYRSYQAVLDAILKQNADIGLIV
ATGDLVQDQSLEAYRHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGK
HWQLLMLDSQVQGVPHGELSEYQLEWMKKCLDRYPERYAVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQGYSRVKAMLCGHIHQEMDLDWNGIRMMATPSTCLQFKPHCTNFMLDTVA
PGWRYLELSVADNGEFGLTTQVYRLASNEFCPDLDSDGY
>A0A5I4KB20|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Aberdeen|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5I3D077|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Berkeley|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2A4GHR7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salinivibrio sp. YCSC6|TrEMBL
MQPCQIENANGDCIRLLQITDTHLFADEQGSLLGVNTLHSYHAVLDAISATQRTFDAIIA
TGDLSQDHSALSYRRFVDGIQRWQQPCFWLPGNHDFQPEMRSVLQSGSLSHCSQVLLGEH
WQMILLDSQVSGVPHGELSSEQLRLLDQHLSEYPQRHALVLLHHHPLEAGSTWLDQHKLV
NRERFWQIMAAHPQAKAVVCGHIHQALNVRHQGVQVMASPSTCIQFMPDSHDFALDNQNP
GWRWLDLYSDGRIESQVERVTGQQFRPDFDSSGY
>A0A8I0VCI6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. SK-43|TrEMBL
MTFQVSTLSQKDFVMIQITDTHLLEYPHLEFVGMQPEQSFHAVIDLMRQTHPEIDLIVHT
GDLAQNPTPLTYHRYLEYMHSLSIPFFQTPGNHDDVNHFPFHEQDKTAPTVVELGNWCVI
LLNSAQPNRIDGKIADAQLQQLPKLLTQLHDRYVMIACHHHPFAMQSAWIDQHKLKNSSD
LLETIQPFSNVKAIICGHVHQDSITSWQGIEFLSTPSTCIQFKPKSEKFALDEEHPGYRY
IRLKADGEIETQVHRLSNSQRLSSSEVLGYD
>A0A653X1U5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Curtobacterium sp. 8I-2|TrEMBL
MDSRTAEHPRPNHFLLHLSDTHLVSGDRDLYGDVDSAARLTQIVADIEASGTRPEAIVVT
GDVADKGEPGAYARVRAILEPAAERIGAQVIWAMGNHDERGAFRRELFGLQPTDRPVDFV
YDVNGLRVITLDTSVPGHHHGEVSPEQLDWLAEVLSEAAPHGTILAMHHPPVPSVQDLTV
LVELRDQQALAEVVEGSDVLAIIAGHLHYSTSAVFAGIPVSVASATCYTQDLTEYQGGTR
GRDGAQSFNLVHVYGHNVVHSVVPIGHYATVGQPVSALETEAKLAAHGVTIPAAVEPAPV
TSSIPVFTLDSVPVSPVHR
>A0A5W3RVL0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Cardoner|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFCAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A088MZ95|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Baumannia cicadellinicola|TrEMBL
MESLLKLPVACGANIRILQITDTHLFASKHDTLLGVKTFYSYNAVLDAVQATDDHFDLVV
VTGDLAQDYSPNAYRHFASGMTRLPAPCVWLPGNHDYQPVMVNILAEYGISPAKQVIMGE
NWQLLLLDSQVYGVPYGKLSDYQLKWLVKILVQQPLRHTILLLHHHPCPSGSIWLDQHRL
GNAHRLAEVLQQHPLVHTLLCGHIHQELDVNWQGRRVLASPSTCVQFKPHHTSFTIDTVG
PGWRYLDLTLEGDVYTEVRRLTSHEYLPDINNEGY
>A0A2H6AZS9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR40|TrEMBL
MRLAHLSDPHLAPLPCPRARDLLGKRASGFLSWQLRRRFRHRPEVLEAVVADLRAFAPDH
IVVTGDLANLSLPEEFVRAARWLAGLGSPERVSLVPGNHDAYVRLAPEQSAAQWTPWITD
DDGRSGFPWLRRRPPLALIGLSSAVPSAWFRATGSVGETQLEALERMLADLGDEDLIRVL
LVHHPPLERVPRRKALLDREALLRVIARHGVELVLAGHLHRFAVEWLFGPRQPVPLLLAP
SASLLSSAEGCGGYVRLVVEGTRRQPRIEVELRRFDPGSGRVTGTGRFSLSAAAAGRAEA
EMALP
>A0A849MG20|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteobacteria bacterium|TrEMBL
MTANTIKIIQITDTHIIDDGAPSFNDFDTTASLHQVVEKIREDEHDADCVLLTGDLVHDA
TKSSYQKLADLLSSLTTPLLSLPGNHDLPELMDYVMGANGYDTGKIFKMEPWLIILLDSC
VIGEHSGDLADSELDFLRSTLESNRTSYCLIALHHHPVSVHSSWMDSMILKNAEDFLNII
DEFEHVRGIIWGHIHQEFKTMRNKVCLLGSPSTCLQFKPKSDIFAVDKKPPAYRKLELLE
DGTLKTEVIYLLI
>A0A8F8CBW5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. AO-1|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEADGTLLGMNTRESLQKVIEQVLKQQPRIDLMLAT
GDLSQDGTLESYQLFRQMTAQIDAPARWIPGNHDEPQIMAQAAVQSALLESVVDVGNWRV
TLLDSAVPGSVPGYLQDDQLQLLARSLSEAPERHHLVCFHHHPVSIGCPWMEPIGLRNPE
AFFDVLDRFPQARAVLWGHVHQEIDRERNGVRLMASPSTCIQFEPGSHDFKVGEQAPGYR
WLRLLPDGRLETGVERVTDFEFTVDYGSNGY
>A0A5X7K0P5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Strasbourg|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A6N3IDA7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Desulfovibrio sp. 86|TrEMBL
MRILQLSDTHLRGDNKLSFRVVDTRRCLDATVAHLKSMAQKPDVIILSGDLADSGDLNAY
HILTELFSPLNIPIYALPGNHDRRDRMQNVLKDWCPSDPDVAPHICYTVEMDDLRLVVLD
STHPGSHSGHFFPAVETWLTGELRKRPQVQTLLFMHHPPFTTGLGVMDEPFENQQLFAAL
VADNPQLRLCFGHMHRPIITQWQGRLCVTAPSAAMQIDLDLSPEGGDTFVMEAPGYLLHH
WENQTLNTHVCQIPTNVTFDGPYPFADSVNPVGPSD
>A0A6I1YR33|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces sp. RB17|TrEMBL
MIRIAAVGDIHMSPESQGTLRSSFLTLRECADVLLLAGDLTRHGTPEEAAVVAREIKDLG
VPVVAVLGNHDHHDERPEEVAAILRDAGAHVLEGESAVVGTGETRIGVAGTKGFGGGFVG
ACAGEFGEPLMKEFVRYSRRCADGLHAALKDLADRNCDVRIALTHFSPVPDTLAGEPQEI
YPFLGSYLLAEAIDTAGADLAVHGHAHAGTEHGMTSGGIRVRNVAQPVIGQAFHVYNLPD
HEEHPQG
>A0A8C9PE96|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Spermophilus dauricus|TrEMBL
MLRTSLLQLTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREPQEPMSQITGVK
KLMHSRSPNTSVPRFGVKTDQEDLLAQELENLSKWGLNIFCVSDYAGGRSLSCIMYTIFQ
ERDLLKKFHIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTD
LEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEENCD
IFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYADRI
QVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEK
SQVLSSMFLADVASFPIFVDMPPLVCGDGGSYSHPSLSRWNIVNGWNCA
>A0A4Q6D007|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moraxellaceae bacterium|TrEMBL
MWRCNGWLCGFRLRLIAQYESTRPDVNDATRLTLQREQEAGFIVIYQVELPAPVLADQRP
IRLVQCSDMHLFANPDSQLLGLNTQHSFEQVVALVKQQQPSIDLLLTTGDIAQQSEPATY
QRFLQTMQPLDAAHFCIPGNHDLSHAYDHHLPLNQLPCEVVIGNWCCILLDSSVDHEIAG
SFSQRMLDYLEQALQRQHDKHILIALHHNPIAVGCVWLDQHMLKTHHAFFEVIANHPQVK
LVIHGHVHQEFEQQHRGVTYLSCPATSLQFKPHSVKFTLDRVSPGYRQFDLHTDGRFETQ
VHRLQDYHFSVDFQSLGY
>A0A448SBV7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia rubidaea|TrEMBL
MESLFKLPVASGAKVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAVRAQQREFDLVV
ATGDLAQDHTPEAYRHFADGISQLPAPCVWLPGNHDFQPAMVDALAAAGITPSKHVLLGA
HWQVILLDSQVFGVPHGELSEYQLEWMERCLQAYPDRYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAVLLRYPKVNTLLCGHIHQELDLSWQGRRLLASPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVCRLDNDDFRPDMDSDGY
>A0A2N7MBW7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIEPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDG
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPDRNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAILCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTQVRRLPSGQFSPDFDAGGY
>A0A3G2IEN4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Buttiauxella sp. 3AFRM03|TrEMBL
MESLLNLPVAGGGQIRILQITDTHLFSGKNETLLGINTWMSYQAVIAAILAEQRQYDLIV
ATGDLAQDHSAQAYQHFVEGIAEIPAPCVWLPGNHDFQPAMFSSLLEAGISPAKQVFLGD
NWQILLLDSQVFGVPHGELSDYQLDWLERKLAAEPERHTLLLLHHHPVPAGCSWLDQHSL
RNAAELDNVLQKFPKVKTLVCGHIHQELDLDWNGRRMLATPSTCVQFKPHCSNFTLDTIE
PGWRWLELHPNGEVTTEVCRLKGAVFNPDTASEGY
>A0A649YSI6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. THAF191d|TrEMBL
MKVTSCSSDGSIRLLQITDTHLFEATDGSLLSVNTADSFNAVVDAIVEESPAYDAVLATG
DISQDHSEVSYQRFEQGIVPLKKKCFWLPGNHDFKPSMNSVIPSQQIQQIDHVLLGDTWQ
MIMLDSQVVGVPHGRLSDKQLNLLEEKLSQYPERYTLILLHHHPLLVGSVWLDQHTLKDS
DDFWQVVDQHNNVKAVLCGHVHQDMNVMRNDVRVMATPSTCVQFKPNSDDFALDYQSPGW
RELLLRDNGEVETQVKRLPAGCFQPDFNSAGY
>A0A2J7W5A0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Variovorax sp. B4|TrEMBL
MPLRPITLLVTLLHAYIGLRLLPALALLTGAWPLLLALLVLSAATMPLPFVGARGIGRRA
PLSDGWKWLGLLSMGWFSSMFVLTLVRDLGLLLGWIVAVLGGWAFDSPRSQAWSAAAVPF
MATLVSLIGFFNARRTASVVRVEVPIRDLPAGLEGFTIAQLSDIHVGTTIRRGYLQRIVD
AVNRLGADMVAITGDLVDGTVAELREHVAPLADLRARHGTFVVTGNHEYYAGAHAWIDEL
RRLGLRVLLNEHVVLQTRNVKGAQTDEEAFDSALLVAGVTDYTAAHFDAAHASDPLRALH
DAPPLVRIRLLLAHQPRSAPAAADAGYQLQLSGHTHGGQFFPWNLFVPLQQPFTAGLHRL
REMWIYTSRGTGYWGPPKRFGAPSEITLLRLVPERP
>A0A4Z0I9V5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. E5028|TrEMBL
MESLLTLPLAGESRVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADSRFQPDTASEGY
>A0A498U5C8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacillus safensis|TrEMBL
MVNVSRQIMLLCFFIILFCFSQPASAGPFLQTEVNVPDKPFSPFIFDQFHVDVRPVLGKS
HDLQFRASISDQEQILSANLYYKQSDELGYRLIPMERLPGMKPEFTAKIPPDQLWNPTVR
YYTEFLTQKSVIKTAEKSVHLNGFEEDLSHIPDLFITEIVVNSKNRKGKDAFEFIEVYNT
THAPISLKHYQLRYRNPAQGIEMDDVYSFHTNPVTISPGKPYVFWLRKKGQEHLTAADFN
AMYKSQLKEGEHLSIIESKGLSNSKSRLVSITTNIGEEISSAAFRLKPSWFSEHKSLLFK
YPMDGTTQTKLISKIEEEPTPGKVLKAQIPSEKKEISQDIHKPVIEDMTVRKPVKPTESV
EIKADVQDDQAVKTVKLRYRTNRKDAFKEILLQKDHNDRLFHHIIYSPELIGKEQLEYQL
EASDGGNEAKTLKKTIDVEQVSKAHGLRFNVEEGDTVSGLFSLKATSDQKKSIELRIDGK
RNQQVSSALEADPYIAFDVKGTNLYFKNGVSIGRRLLSIFDDSTKVYRTYTMPIPEEEIK
KAGLQTISFHAGTKSSPMDRLPGENHDDFELKNVRMILSNGTQIPPINAKPLKEWRMGDS
GNAKKVRTFQFEIPKEAYVSTYIKWDTKRLKEGPHLIEAKTSDEHASVRVKVDNTGPRIK
TNVQAKDQYKGAFTLKAKVTDRWSDIEELKAYVDGKPVSLPYQTSSSELKPGKHTFTIKA
KDAAGNMSTLKKEFKTVHEHPETPERVADKTKMKSSKQTVLTKDPTNDKLDYSFYRAYQY
TSLHPSMKIFKYAAETEPPKSYLQKGEMIFSDQERNRIAFVDGKSVETKDLQRFPYHRFQ
IKVHHDVREKDVVEAVWKGSSLSGRKVTMYAWNHQQEKWDKITHHFAKDQKEFYLKGLLS
VRQYMKNQTFDLLVQDEISKSQKPYKMVWMSDTQYYAKSYPHIFKQMVEWIRDQREKLNI
QYVFHTGDIVDDSKDKQWHRADTFMRVLDQNHIPYGVLAGNHDVRHKDGLYAEYGKYFGE
KRFADKPYYGESYRNNKGHYDLISAGGNDYMMVYMGWGIKQDEIDWLNRVISEHPDRIVI
LNFHEYLLVSGNRSPIGDLIFHQVVKRHPNIVAVFSGHYHGASRKVDELDDDHDGKVDRK
VYQILADYQSGPEGGQGFMRVITADQEKNQLHFTTYSPYLNQEHFYDPKTYGDQDEFSID
VDLTPKMKSVKTNYFELNVYTNVLLGEARGVKSGKKASFEWKGLKPNEDYYWYTVAKDRF
QGKAISPIWKIHTKDDDETKFLRK
>A0A6G2EGU8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. JL972|TrEMBL
MLGASLTAAEESVLLVQLTDSHLFAPAQGTLLGMDTCDSLQRVIDLVLEEQPHIDLLLAT
GDLSQDGSFESYQRFRELSTRIAAPARWCPGNHDEREAMREATRGTSLMEPVFECDNWRV
ILLDTLQSGEVFGVLDEPQFEWLDATLRAAPEQHHLICLHHHPVTIGSRWMDSIGLREPE
RLFEVLDRHRNVRALLWGHIHQEFEQVRNGVRLLASPSTGVQFAPRSERFKVDSLAPGYR
WLRLHGDGRLDTGVSRVSGIDFEVDYSVKGY
>G5S140|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Urbana str. R8-2977|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>B8ED43|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella baltica (strain OS223)|TrEMBL
MLKEAVSYSIAEGESVRIVQVTDPHLFADPEAQLLGVNTGKSFDAVLNTIRAVDYPAHLM
LATGDLSQDYSAESYQQFVKAVTPVGLPCHYLPGNHDDPRIMYLHMQGEQIFGQQRILAG
NWQILMLDSTVRGKPGGNMAETQFELIDEAIAAHPECHTLLVMHHNPIVVNCTWLDQHCM
DNGAEFIARVAKYPQVKGLLWGHVHQCIDTHHNGPHGSMQLMATPSTCIQFKPLSPYFAL
DSVQPGYRLLELKADGSINTKVYRVPGNHFSPDNNSSGY
>A0A845MSI8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alcanivorax sp. DP30|TrEMBL
MTQQLQPLRIVQLSDCHLFADVSGKLLGLNTQFSLDKVLELIRKEQPNPDLILATGDLSQ
DASFESYQRLDDALSTFQVPVYWLEGNHDKPAPMLEALHAQRDRMSPCVLELDHWTIVML
DSTIPGEVPGELFDEDLKFLDDALANAKGEHLMVCLHHHPVPMGCAWLDTQVVGSANKFF
DVIDRHPRVRAIIWGHVHQEYDSERNGVRMMAVPSTCVQFKPFSEDFAVDDTNPGYRWLD
LHADGRIDTGVSRVEGITFEVDFSVKGY
>A0A060W8K0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oncorhynchus mykiss|TrEMBL
MVLGNWAVGAMYRRSPCHRSRAHFDFSEDVVKGLHASSHTHSFDVENGPSASCSPLDPSA
SPGSGLVLHTNFPGHNQRRESFLYRSDSDYDLSPKSMSRNSSIASELHGDDLIVTPFAQV
LASLRSVRNNFTVLTNVQCASNK
>A0A060YJY0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oncorhynchus mykiss|TrEMBL
MLNRELTQLSETSRSGNQVSEFIANTFLEKQQDVEIMSGPLKDKDKKKRPMSQIVAVKKP
ALSPSLAPTQIPRFGVTTLQEGLLATEFEDINRWGLDIFKIAEYSGNRPLTVVMYSIFQE
RELLKNFKIPADTFVTFMMTLEDHYHTDVAYHNNIHAADVVQSTHILLSTPALEVWAPL
>A0A3Q1APH2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Amphiprion ocellaris|TrEMBL
IQILRYYVLTFSPFFLHSFDVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLYR
SDSDFDLSPKAMSRNSSTASDLHGEDMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNKR
PSSSNQPSMCKPCVAGQC
>A0A060Z2F3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oncorhynchus mykiss|TrEMBL
MVLCHFVSPQFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQNELELPCPMAKTREWK
KRPHHQTQLEGQGTLTQISGVRKLSHSTGLQGSSISRFGVKTDQEDLLSKDLENINKWGL
NIFRVAEHSHNRPLTCTMYTIFQVSVLPLSLLPLSLLSECSVSLQAHAHTHTHTRAHTHT
RAHTHARTHAHTHARTRTHTHTHARTHTRAHTTXXTHTYTHNQTHTTLSPPLCCR
>A0A094LLK7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella mangrovi|TrEMBL
MLKEAITYSIPKDHSVRLVQMTDPHLFAEPDGNLLGVNTANSLAAVVSTVQALNYPADLL
LATGDISQDFSAESYRNFVKAIAPLDLPCHYLPGNHDDPRIMNLHMQGERVFGQQRIIIG
NWQLILLDSTVRGKPGGHLDESEFALIREAIAAEPDKHVLLVMHHNPVQVKCTWLDQHWM
DNGAEFLAEMASYPQVKGMLWGHVHQQLDHTIDGQHGPINLMATPSTCIQFKPLSTYFAL
DMVQPGYRLLELRADGSMQTSVYRVPGERFSPDVKASGY
>A0A679JW41|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hyphomicrobium sp. ghe19|TrEMBL
MTRLGINGSSLESTLSTRQVADLWKGIVMSDSKDDEGVSRRHALECMIWAGTGVFWTVAG
GVPTSLSLLDAAEAAAAATSGFTFLQISDSHVGFNKPANPHALDTLKEAIARIDALPAKP
TFMLHTGDITHSAKPAEFDLANQVIGSTGVDVHYVPGEHDITDEATERAYLERYGKGTKG
GGWYSFDDNGVHFIGLNNVVNLKQFGLGYLGNEQLEWLEDDLRPLKSSTPIVIFAHIPLW
SVYPNWGWGTDDAAIALGYLKRFGSVTVLNGHIHQLMQKVEGNITFHTARSTAFPQPAPG
TAPSPGPMVVPAEKLRSVLGITNVAFKRTDSPLAITDTSLAE
>A0A5X3NYM4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Weslaco|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A8C9SNS7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Scleropages formosus|TrEMBL
GGGGESRLQSCVSHSLEVDNVPSQERSPLDSQASPGLLLHPYFALSQRRESFLYRSDSDY
DLSPKAMSRNSSLTSEGLTEDFIVTPFAQVLASLRSVRSNFALLANVSSPTVKSVHVTLV
LPSCDLTEETYQQLARETLEELDWCLDQLETIQTHRSVSDMASTKFKRMLNRELSHLSEM
SRSGVQVSEYISSTFLDKQNEVELLPPNQKEQNSAPCQTSGVGVLSEDSRATLPRFGVHT
EHEDVLAQELENLDKWNFSIFTVAQLSCNRPLSCIMFAIFQERDLMKTFRMPEDTLMAYV
MTLEDHYHASVSYHNSLHAADVTQSTHVLLSTPALKAVFTDLEILAALFAAAIHDADHPG
VSNQFLINTNSELALMYNDESVLENHHLAVGFKLLYEENCDIFQNLSKRQRQSLRRMVID
MVLATDMSKHMSLLANLKTMVETKKVTSSGVLLLDHYTDRIEVLRIMVHCADLSNPTKPL
AVYRQWTERIMEEFFRQGDKERERGMEISAMCDRHTASVEKSQVQTGCVCVCVCVLQANC
TDGCISAVTWAGFVYRYVCVFVLL
>S4YT70|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia plymuthica S13|TrEMBL
MESLFKLTVASGARVRILQITDTHLFAGENETLLGINTYRSYHAVLDAIMAQQRDFDLVV
ATGDLAQDHSLAAYRHFAEGIARLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLLGE
NWQVLLLDSQVFGVPHGELSDYQLEWMERCLQAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAVLLRYPNVNTVVCGHIHQDLDLEWQGRRLLASPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSEGY
>A0A387HHG7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces hundungensis|TrEMBL
MDIPRFGIPDRLAERMSMAEQHEYLRSRLSRRGLLRTSAATAAVAGAGLATAGAASPAYA
APTALTSTSRHGVDGSLAAPFGRHLAYGADPKTQMRVSWQVPFAVRKPYIRIGTSPWSLS
RKIDAEVRHLTTPALNGGKIAAAEQFYVHAGLDRLRPGQTYYYGVGHDGFDPADRRNLGT
LGTFTTAPGHAENFTFTAFGDQGVSYHALGNDQVILGQNPAFHLHAGDICYADPSGSGQS
SDQYDARTWDQFLAQTESVAKAVPWMVTTGNHDMEAWYSPQGYGGQNARWSLPANGPDPV
NQPGVYSFVHGNVGVVALDANDVSYEIPANFGISGGKQTTWLDKRLGELRADHAVDFVVV
FFHHCAFSTTSSHASEGGVRDAWVPLFEKHQVDLVINGHNHVYERTDAIKGNKVGRKVAI
GERTDPTRDGIVYVTAGAAGRSLYSFPVPDSYEGHVADRDSVNTYHWAKGGAKVTETVEW
SRVRYTNYSFLAVEVETGRRPKMKVSALAETGERIDHFEIQRGR
>A0A5D0VTS1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter sp. BW6|TrEMBL
MTTKEQARPLRVLQLTDPHLMARADGDLLGVKTRESLQAVIAEVLKIHGQPDLILATGDL
AQDGSLEAYRVFGESLSVFSCPSVWIAGNHDHADNLVKAAGEYNACHRHVIRGGWQFVML
DSSVPGKVFGALAESELDFLSETLERHPDLPAVIALHHHPVDIGSDWMEKIGLTNRDAFW
QVVDRFPQVRIVLWGHIHQEHERERNGVQLMATPSTCIQFTSGSSKFSVEDLPPGYRWFE
FHDSGDFATEVRRAEDFQFELDQNSSGY
>A0A2S3W579|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Novacetimonas maltaceti|TrEMBL
MTDILIAHASDLHLTLDTLRIRARDLLNKRALSYLSWQRRRLIHRTDMLRRVMADITAHK
VDMLAVTGDLTNLGLPDECAQAARWLSELPMPVTVVPGNHDALVSSDWHQSIGRWAPWMG
PLPFPFVRRVGPVALIGINSAHPTPCFQASGDIGAHQAARLADALEETGRQGLCRVVMIH
HPPLARLTPRRKSLRDADRFAACIARHGAELVLHGHTHVSTIATLPAPDGPVPVVGVASA
SARSPDPARAASWNLVHISPAANGGYRTEITRRIMLPDGRATATPPIIFTPAASSPVHSG
ISTPR
>A0A845FQJ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomaricurvus sp. HS19|TrEMBL
MDLRPAPQRVLQISDSHLGGRPGETLLGLDTDESLQDVLQRLRQREQHADYVVATGDISS
NGQMAAYERFLRSMESGYGRPLAWLAGNHDRDQSMCTFPRERVARELVELDHWQLILLNS
SLPGHEHGLIGDQELQRLEQQLQGCDKHALVFVHHQPVLVGSRWIDQYVIRNAGALLGLL
SRYPHVRALCWGHVHQDFSSRWGHFGLYSAPSTCIQFKPRCDDFALDTAMPGYRWFDLHA
NGELQTGVERTAEKSYAIDFASGGY
>E8LNB7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio brasiliensis LMG 20546|TrEMBL
MKVTSSSSDSGTIKLLQITDTHLFEPADGSLLSVKTLDSFNAVVDAILQEKRLFDAILST
GDISQDHSAQSYQRFEQGIAPLEKTCFWLPGNHDFKPSMTSVLPSTQIQQAEHVLLGDKW
QMVLLDSQVVGVPHGRLSDQQLALLDQKLSEHPERYTLVLLHHHPLLVGSRWLDQHTLKD
AQDFWQVVEKHNSVKAVLCGHVHQDMDVMHKGARVMATPSTCVQFKPNSDDFALDTLSPG
WRELELHLDGTVSTEVKRLPAGCFQPDFNSAGY
>A0A5F1HB14|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. E4385|TrEMBL
MESLLTLPLAGESRVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADSRFQPDTASEGY
>A0A7W3D9A8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter freundii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQCILDAIHAESTDFDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPSGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIS
PGWRTLELFADGSLHTQVCRLPGIRFHPDTASEGY
>S1ENQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli KTE73|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7W2LK76|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas juntendi|TrEMBL
MHADHPRPVHVVQLTDAHLFADPAGSMLGLKTRESLGHVVAQVRREQPLVDLLLCTGDLS
QDASVASYEAFRELTAPFGVQSRWLPGNHDEARIMAEVAPELVQAVTDIGAWRIVMLNTA
VHGATHGLLGDDQLAVLEAALKGAGGRHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDII
EGYPQVRALLWGHVHQEWDEVRDGRRLLATPSTCIQFAARSEDFKVSEEQPGYRWLRLHA
DGRLETGVERAWDFEVKLDFDSPGY
>A0A5I4V2U4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Oslo|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A1B1BY87|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio crassostreae 9CS106|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPHGQFLPDFKAAGY
>K7FMI2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pelodiscus sinensis|TrEMBL
PEETYQQMAKETLEELDWCLDQLETIQTYRSVSEMASNKVGLLTHGWYLQLSLLRSGTLR
PFFNSSISLYKQNDVEIPSPTPKEREKKKKQQPMCQISGVKKLMPSSSLANSSVPRFGVR
TDQEELLSQELENLNKWGLNIFHVSEYSNGRSLSCIMYTIFQERELLKTFKIPEETLLTY
MLTLEEHYHADVAYHNSLHAADVVQSDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINT
SECPTTLRLSRQDAPDQGLLGQPPPDPPEIRARRAGHPQTPPRSGPVGPGAPRPPRDQGP
SGQEPHRSQLLQFPAFGPAFQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRDWYHS
MIPQSPSPPPD
>A0A5A5S0A1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcystis aeruginosa NIES-2521|TrEMBL
MQRRKFLLISGSLGGFSLVACAHQILQPVTSKNPPESSVKQAQKAKKVKIIVISDLNSQY
GSTTYDPEIDRAIPLIINHKPDLVLCGGDMVAGQKSSLTEAAINAMWSAFDHHIAAPLRA
AKIPFGFTIGNHDASGALSAGKFIYAQERKLSRDYWQNPQHETSLNFIDKTGFPFYYTFT
QNGIFYLVWDASTHLISREQLNWAAKNLSSPDAKNAKMRLVIGHLPLYGIAVGRNRPGDY
LADAEQLRAFLEGHQVHTYISGHAHAYYPGKRGQLQLLHAGALGSGPRRLLNSEQAPRKT
LTIVDINPHQQETVYTTYDMKTQEAIDITSLPPLIMAPNGQVLRRDIPSVN
>A0A7U2ZSQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella africana|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVFLGD
HWQILLLDSQVFGVPHGELSDFQLEWLEQKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAEFHPDIASEGY
>A0A808U438|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGKH
WQAVLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLVPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTQVKRIQQAEFLPNMQEDGY
>A0A6G8NW62|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Caballeronia sp. SBC1|TrEMBL
MPDLDKKILPPDPLTAHGARRRTALTCMAWAGAGMLWTLNGGVPGSKLIGGTAQAAETDR
HAFSFVQISDSHIGFSKDPNLDPASTLSEAVDKIRASSEKPRFIIHTGDISHLSKPGEFD
TATQIIQSAGLDVHYVPGEHDVLVDDGGSYFERFAKPADPKWYSFDQGGVHFIGLTNVLD
LRGGGLGFLGDEQLAWLKQDLHARTSSTPIVVFAHIPLWSLYPQWGWGTDDSAQALAMMK
RFGSVTVLNGHVHQVAQKVEGEINFYSALSTAFPQPAPGTAAGPGPMKVPADTLRKMLGV
RTVNYVPGKAELAIVDTRLSV
>A0A0E0XXL6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O104:H4 (strain 2011C-3493)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A743ZF31|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMHSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A379QFB6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQHEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCTNFTLDTIA
PGWRTLELQANGSLETEVHRLQDTRFRPDTASEGY
>A0A6P4GLA3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila takahashii|TrEMBL
MRNCLPKFSKVFRRKSSAAKSSSSAGGRENPSNEPDSDTEPYAIAPSAISDSDRGGGHNE
RTRPLDDDSSRSRLISAAHSDLYMDLDSDSPANGGIRPKSEGARPEMKVETTQAKTPGPV
AISLPFVGRNSCKTPEEMELEYEANVEAESRDIMTPLRRKTRPLSVAFSGGGGGGVGGGR
NSLQPEIVEAIRSLDVPALLLNNLSLEGRESSLHLEDGSLCHDHEEAVVLRRKVNCLERK
SHSLYERRLPKVPKLHLLVAGKKPTEEEEFRTFQVALAEVANFSSLAHQSTIRHTHGHHL
TTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMSTQ
QALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSDLSTISEQ
CKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQP
KEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQENCSAD
EARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTG
SSTRTATIVPAKMKSNPIIMELLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFA
TLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDMHVMDRMEEA
TALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLGDDKINIFK
NLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPREHNSQTDEEQSILMRRM
LIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRATCSIPKSQIG
FIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLAEIMAKQPPVGKMANS
K
>A0A403FJL3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enteritidis|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLVLQANGVLETEVHRLQDTRFRPDTASEGY
>C9PMZ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurella dagmatis ATCC 43325|TrEMBL
MFKFIQVTDPHLFREENSELLGVKTYQSFVQVLDEIKEQDFDYDFVLATGDLVQDNSDEG
YLLFCEQVKRLDKTVFWIPGNHDFQPKMFAILNQNQGNLNAKKHIVLGKYWQILMLDSQV
FGVPHGELSQYQIDWLVSKLKDNPERYTLIVLHHHILPTNSAWLDQHNLRNAHELAYALS
PFDKVKGILHGHIHQEVDAEWNGYRVMATPATCIQFKPDNNTFALDCAQPGWREIELYAD
GRIETRVKRIQKAQFLPNMNEEGY
>A0A1B7HGU9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Buttiauxella noackiae ATCC 51607|TrEMBL
MESLLNLPVAGGGQIRILQITDTHLFSGKNETLLGINTWMSYQAVIDAILAEQRHYDLIV
ATGDLAQDHSAQAYQHFVEGIAEIPAPCVWLPGNHDFQPAMFSSLLEAGISPAKQVFLGD
SWQILLLDSQVFGVPHGELSDYQLDWLERKLAGAPERHTLLLLHHHPVPAGCSWLDQHSL
RNAAELDNVLQKFPKVKTLVCGHIHQELDLDWNGRRMLATPSTCVQFKPHCSNFTLDTIE
PGWRWLELHPNGGVTTEVCRLKGAVFNPDTASEGY
>A0A7X1PRE6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas piscis|TrEMBL
MPSVSASPTDDSVLLVQLSDSHLFAETHGTLLGMNTADSLQRVIDLVLAQQPKVDLVLAT
GDLSQDGSLQSYQRFHQLSAQIPAPARWLPGNHDEPGIMQLAAQGSELLQPVVDIGNWRI
TLLDSSVPGSVPGFLQDEQLQLLARSLDEAPGRHHLVCLHHHPVSIDCAWMEPIGLRNAE
ALFEVIEGRPQVRALLWGHVHQEIDRRRGGLRLLASPSTCIQFEPRSDDFKVEERAPGYR
WLRLLADGRLETGVQRVEGYAFTVDYGSDGY
>A0A5E4B0S6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marmota monax|TrEMBL
MLLGSPFLPDCKSCLLSRHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNKRSPAAS
QPPVSRVNLQGFPTVMDGMSCSFPPEEHPSEL
>A0A3S0IS03|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella canadensis|TrEMBL
MLKEAISYSIDDNASVRVVQITDPHLFADPDAQLLGVNTAQSLDAVLNTINAVHYPADFM
LATGDISQDYSGESYHNFVRAIAPLELPCHYLPGNHDDPRIMRLNMQGPKIFGQRRILAG
NWQILMLDSTVRGKPGGHMSDSEIDIIKSAIADQPDRYTLLVMHHNPILVNCAWLDQHCM
DNGSDFIEQVAELPQVKGLLWGHVHQKLDQKHPGKHGIMHLMATPSTCIQFKPKSSYFAL
DALQPGYRLLELKADGTILTNIYRVPGDNFSPDRDASGY
>A0A6J1M817|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila hydei|TrEMBL
MRNCLPKIFRTKSSSSVSSASSARAAAVHSNELDADSDAERYVVAKTKTTATTTTLKGAA
DQRLDKNANKKLHQQQQQQQQPQQPPATTTTTTSTTSTSTTSSADDVDKNRLISADKIAN
STSLDLETSNNSHNHSQSNSNSNGNGNGNQTATNGSIRQVHDTNPTSEMKVACGEILLPA
PVPVPLSLPLAVPAPTSISVPVLPGNSSKTPEQMEREYEANEAAEGRDIMTPLLRSTRSL
SMAFASGAGPGGGGGCGGGAAGVGRIMQPEIVEAIRNLDTQALRLNNLTLEDRVKLTQRQ
DAKAKENNDNVTLRPKVFTFDRQTHSLYERRLHKGPKLRLWVGNGKKPSPQTEEDEFKSF
QRNLMDLKYPTVLPPNPQLKALLVFHKSDSICEVVTLACQRHQLDVTLVKSKEEALETLH
KSYATAQCYHLIIIDARSTKGLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDALIAL
LDAGVNRCIAETTNLTLCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVL
RIQYANRATERLLNMRLDEIISKPLGDIFVSDLSTISEQGKSIKEFDGILMVRRKNQESI
PMHVRVVPVACIGSAPTHLIFNFDIPGGGMDFIATLPQPKEAPRGSLHSVRRCSFDVRSI
ASDGLRRTSLAKLTSLPLEAPITKENCSADEARLIDKVLDFLKREGLYSPQMKEIRTDDP
IATDLIGALLTGPSVYSSRRSSNDSIIRTGNSTRTATIVPAKMKANPIIMELLEESLKWD
FDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNST
HAADVMQATGAFITQLASKDMVMDRMDEATALIAAAAHDVDHPGRSSAFLCNSNNPLAIL
YNDLTVLESHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLA
KFVSVFGNEMEPRELVQSEEETSILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYFMQ
TDEEKQRHMPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWDGFIDMPELITCMQINYS
QWKKYDEQGVNTLADIMAKQPPVGNKSSSSK
>A0A1W4X9D6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Agrilus planipennis|TrEMBL
MDDNSSYNESQQNNRSLNRQLRSNCWYQLFYYTRACNRPKSARNSQLHIRKRIVVDQANK
STFVNESELDQYDYTTNVKDKIIIPSPYVEYASLANHRQSGECTKVTYPIFIRSKRVSDE
SEDKYITEIYAEDDIPSTLDASYSKIDPNNLSIALRRSMESIRKDTTSLPPMSQVSLPKK
QQKKSSKFDIELPYSSFDVCCKKQERFRRILGGYSTHPKYQSEKFSDREQINVFVRKNPK
LLIFSETQDETVKNIQLAAQQLQIKCVRFDEVRDIEDSHQPTDVIIVDVRTMGAIPQDVR
ALCESCRKCIQQVMIIALVKTEDFEKNNLKILHLLDIGFTRCLAENSIYTACYNELIMIF
QSDLKMSLRGFTFSAIFFATSISTSDLILVLDNEYYIRHCSISIKEHLQYEIEDVLGKNI
REKLMTGSSIFSSFERAISGSSSWRGTLQMENKNGETVAAQCNACTLFDDNRTFSHIVMS
LYVYGPLREKKVSVSTGRSEFMLINIVNAINLIDEARNKCERESETYLLLTKVVNLLDNV
NVVKTVKMIDQISEPIASDLITALLDTKQSTSRIGMDTKSSRKQAASKIFTDENQNYLSW
QYDILSEETSCTNILITLGMELFQQFNIPETLNCNESVFKNWFLVMANHYYKEVPYHNST
HAADVMQACAVFLTNKKLGLFLDPNLEAACLISAVVHDLDHHGKSSAFLCNSNHIWALLY
NDLTVLENHHVSLMFQLTLSDDRINIFQNVDIEQYKELRYNIIDLILSTDMTKHFDILTK
FVNEFSAIPYHTEDVLKVINAPDKLILMYRMIIKCADVSNPTRNFNVALEWCRRITEEYC
KQTDEEKSLGLPVVMPMFDRETCSVPKAQIGFIEYIINDLFEAWNAFIDMPELLRNMRKN
YKLWKKLDELGYDTLATLSPDVFNADEIMSTKNIS
>K7ENX7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|TrEMBL
ETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVS
EYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGLKKLMHS
NSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQAVFT
DLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNC
DIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLK
>A0A0G3QM60|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Phytobacter ursingii|TrEMBL
MESLLNLPLAGGARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIQAQQRECDLIV
ATGDLAQDQTAAAYQHFAEGIARFGAPCVWLPGNHDFQPAMYTALQEAGISSSKRVITGD
NWQILLLDSQVFGVPHGELSEFQLDWLEKKLSASPERHTLLLLHHHPLPSGCSWLDQHSL
RNAAELDNVLARFPHVRYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLYPDGSLQTEVCRLQSTRFNPDTASEGY
>A0A7K4EUI1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Halobacteria archaeon|TrEMBL
MSRETTTARPIKVLQITDTHLFDNPDGCLLGLNTEQSLRAVIADVAHRHLPADLVLATGD
LAHTPAPATYARFFSLLGGLGLPVYCLSGNHDEGQMLSTLTDGGLCRFETHLHHGGWHFV
FLDSTIPGSEGAHFPPERLQELDSLLSGAPDTHTLVCMHHQPVAMGSRWLDTMALDNPDE
FFAVIDRHPQIRGILWGHVHQEFTETRNGVQLISTPSTCIQFMPNSSDFAVDMVSPGYRW
LLLHPDGRIETGVERLAAIPGTIDQTASGY
>A0A1Y2SBZ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus vietnamensis|TrEMBL
MIYFTSDTHFCHSNVINLCERPFKSVHHMNNTLIHNWNAYVTKRDEIYILGDFLYRGTGQ
DANQILHRLNGKKFLIRGNHDKFLNDPEFDTSMFEWVKDYYEMDYQKQKIVMFHYPILEW
QGYFRDSIHLYGHVHNASKDPEQLKRLSVLGSRAINVGVDVNNFFPVSINDILRKAQR
>A0A2H6A301|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR33|TrEMBL
MGFGIVHFSDTHFGGKADLAQIEALEALVPDLEPQLVVLSGDVAQRARHGEFQAGRLLVR
ELERTAPVYVLPGNHDVQWWRRPFFPLGSRAKYAKYLRYFGPELAPTLVFPEAIVAGAVT
AHGLAWGSLTWNLRDLAVKGHLPKKEFKRVKALFDSAAPEQARVLVVHHNVLRGELSRRM
GLARWRQAQRRIVESGAEVVLCGHDHQEQVDLLERRVVVSCAGTVSRGSRGGRPSVFNRV
VIHQDAVEVELYRWDAARRQFRRSDVHVFSRWRRTEDDAAEVAVA
>A0A0F8BXW5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Larimichthys crocea|TrEMBL
MKERCSRVPPLAISPPLQQQQQQQAPRVGPVGGCCLGVVGQCSDSMCTVCSDCVSLCADC
LLTDEAYQKLAMETMEELDWCLDQLETIQTYRSVSDMASNKLLKIAFRRHPDSI
>A0A2I3H6F8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nomascus leucogenys|TrEMBL
MPRSSQFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTTEEAPQPMSRI
SGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIM
FSIFQSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLAT
DMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQ
WTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPD
AQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEEEET
ALDKEALELPDTELLSPEAGPDPGDLPLDNQRT
>A0A0S7HFJ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
SAAMDPLGPDYVSVCLLADESYQKLAMETMEELDWCLDQLETIQTHRSVSEMASNKFKRM
LNRELSHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTLREREKPMCHISGVKKLTHSS
SLSNATMPRFGVKTEHEEALARELDDLNKWGLNIFRVAEFSNNRPLSCIMFAIFQVRTLG
KKRIE
>A0A6V8LYD3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Desulfovibrio sp. FSS-1|TrEMBL
MKPAHLPRVALLLLLAALWPGLAASAAECPRVAVLADIHFKAGDAKKLRAVDDLNDWPGL
DLTVVLGDIVARRGTPEEYAQAREFVERIKGPRVLVAGNHEYMYADAEQDGKTPWGSPEL
RREKLERFRRELGAPQLRQARELGGYLLLFLSADAVDGTTLTELSPQSLDWLARTLRDHP
ATPTLIFFHAPLKGTLENYAPKINNKDRVAQPADALDAILRKNAQVIAWVSGHTHTKPDN
PSFLSDVNRYEGRVANVHTPPYKGGAPWTNVFTLCPDKVTVKTWDHAARQWAPGLERVIP
TVR
>A0A6J5G9Y0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia fynbosensis|TrEMBL
MSSHHPIDPARRGALKCLAFGGLGTVFMLAGGVLMPVELALAADGKTPAAAMGTPLFLQI
SDTHIGFNKEANPDVAGTLKQTIEFVNAMPRKPALTIHTGDITHLSKASEFDLAAQLMSG
LSITELHTVPGEHDVTDGPGAEYFRRFGQASDNRGYYSFDHQGVHFVGLVNVMHFKPNGL
GGLGDEQLAWLENDLKGRSSSTPIVVFAHMPMWTIYEPWGWGTGDAGAAMSYLKRFGSVT
VLNGHIHQIVSKVEGNITFHTARSTAYPQPSAGNGEGPGPLKVASDQLPRMLGVTSISIA
QHPLKATLADVTLV
>A0A4Q9EQZ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hafnia paralvei|TrEMBL
MESLFQLTVARGAPVRILQITDTHLFAGEHETLLGVNTHRSYHAVLEAIHAEARPYDIVV
ATGDLAQDHSVAAYQHFANGIATLNKTCLWLPGNHDFQPAMVDTLANAGVNPAKHMLLGD
HWQIILLDSQVFGVPHGELSDYQLEWLERTLSLYPQRHALILLHHHPLPSGCTWLDQHSL
RNAHMLGEVLQHYPLAKTLLCGHIHQDLDLQWEGRRLLATPSTCIQFKPLCTNFTIDTLS
PGWRYLDLHPDGTLTTELHRLDGTEFRPDLDSDGY
>B5FB63|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aliivibrio fischeri (strain MJ11)|TrEMBL
MLSETLLNEESDSIRLLQITDTHLFAPEDGALLGVPTRKSFQSVVEQVLQRTPDFDAILA
TGDISQDHTVESYQHFVKGITPLKKPCFWLPGNHDYKPSMGGVLPSPQISACEHLLIGQH
WQVIILDSQVVGVPHGALSDEQLTLLDNALSQHPQRHSLVLLHHHPLPAGSAWLDQHQLK
ESDQFWSVLAKHRNVNGIVCGHIHQELDRIVNGVRLLATPSTCVQFLPDSDDFALDSQAP
GWRTLDLLPNGDIETQVYRLKDCDFSADSEAGGY
>A0A891SM29|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O157:H-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>D8A7B3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli (strain MS 21-1)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A2J9GYN5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hafnia alvei|TrEMBL
MESLFQLTVARGAPVRILQITDTHLFAGEHETLLGVNTYRSYHAVLEAIHAQSRPYDIVV
ATGDLAQDHSVAAYQHFAKGIATLKKTCLWLPGNHDFQPAMVDTLADAGVNPAKHMLLGD
HWQIILLDSQVFGVPHGELSEYQLEWLDRTLSLYPARHSLILLHHHPLPSGCTWLDQHSL
RNAHMLGEILQHHPLAKTLLCGHIHQDLDLEWQGRRLLATPSTCIQFKPLCTNFTIDTLS
PGWRYLDLHPDGTLTTELHRLEGTEFRPDLDSDGY
>A0A418GQQ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
TLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDL
AQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQIL
LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE
LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT
LELHADGTLTTEVHRLADARFQPDTASEGY
>A0A3N6SID1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia psidii|TrEMBL
MDSLLKIPVESGACIRILQITDPHLFAGKHETLLGVNTWASFDAVLQAISASEQPYDLIV
ATGDLAQDHTVEAYQHFAEGLARLAAPCVWLPGNHDFQPAMYSTLAETQIADAKHVMVGE
CWQIVLLDSQVFGVPHGELSDYQLEWLDNTLAKAPDRHTLVLLHHHPLPCGCNWLDQHSL
RNSPMLEAVLQRYPLASTLVCGHIHQDLDLNWNGRRLLATPSTCVQFKPHCTNFTIDSEA
PGWRWLELYDDGRVETLVQRLQTRAFSPDPDAEGY
>A0A8B9D2T2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anser brachyrhynchus|TrEMBL
QQQGRVENGASPARSPLSPQASPGLVLHPGVPPGQRRESFLYRSDSDYDLSPKAMSRNSS
IASEAHGEDMIVTPFAQVLASLRTIRSNFAVLMHLQDRAGTK
>A0A737RQP3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Sendai|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A834BA12|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Phyllostomus discolor|TrEMBL
MAQQTTSPDTLTVPEVDNLHCSNPWLNEDLVKSLRENLLQHEKSKTARKSISPKLSPVIS
PRNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFV
HSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAAL
TNLQDRAPSKRSPMCNQPSINKATITVWRLYNGIIAFP
>A0A8C0J9E5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chelonoidis abingdonii|TrEMBL
MLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPKFGVKTEQEDVLAKELEDVNKWGLHVFKIAELSGNRPLTVIMHTIFQE
RDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDL
EILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDI
FQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKS
QVSHLNNLLFDTNCRF
>A0A7T4R8W4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oceanospirillaceae bacterium ASx5O|TrEMBL
MYSLDTTTTLRLVQITDTHLNGPEDGHLLGMKTLHSMNCVLDIVRSEQPRMDAILVSGDL
AQDGSVRAYEHLHQALQPFACPVFWFEGNHDNPDNLQQVAAGTEHLQRVIRTPHWQLILL
NSQVIGSVHGHLAADQLQLLEHTLQERPDLHTLVSFHHHPLSMGSRWIDTIGLHNADELL
AIVRRHTNVRCVLWGHVHQESDQIIDGVRYLSTPSTCVQFMPGSDDFAIDTLAPGYRWLD
LHPDGRVDTGVSRVEDIAFDIDYSVKGY
>A0A831W1F7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter antarcticus|TrEMBL
MSSQKITRPLRVLQLTDPHLMASADGALLGVNTRDSLDAVIAQVLKAHGQPDLILATGDL
AQDGSEEAYRVLGDRLGAFACGSAWLAGNHDHAELLGQVAARYGADRRHIVQGGWQFILL
DSSVPEKVFGELAQAELDFLAERLGQHPHLPALVTLHHHPVDIEADWMSDIGLRNRADFW
RVIDRFPQVKVVLWGHIHQAHEQCRNDVQLLATPSTCIQFTSGAREFSVEDLAPGYRWFE
LQASGDFTTQVCRALDFDFELDKNSAGY
>G7PZ78|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Macaca fascicularis|TrEMBL
APSAGRQGRHSLGMRSERGPAPGTPPVPEQSKPGMVAHASTREAEAGESLVAVSQDRATA
LQPGQQSETPNLVVSLGHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPTNKRSPLGGP
TPVCKATLSEETCQQLARETLEELDWCLEQLETMQTYRSVTVSVGGLYAFMVCRGVSKDK
GATRGGGGVHTCSRFPSSADKQNEVEIPSPTMKEREKQQALRPRPSQPPPPPVPHLQPMS
QITGVKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTC
IMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPA
LDVSDCPVSPSPSVFVTAFSGSXXXXXXXXXXXXXXXXXXLMYNDESVLENHHLAVGFKL
LQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDK
HTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEE
ESRGPGHPPPPDKFQFELTLEEEEEEEISMAPIPCTAQEALTAQGLSGAEEALDTTVARE
ASPAQESLDVMAQDESLEAELEEVYLTQQAQSTGSAPVAQDEFSSQEESVVAVSQSSLSA
LALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACTGTSGEDTSAL
PAPGGGGSGGDPT
>A0A502KFY5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus haemolyticus|TrEMBL
MKNTFVYQTEKSIIKLLQITDPHLFKEKETALLGVNTQASFTQVLKEIQQENNTFDIILA
TGDLVQDGSDEGYHRFVEMVTPLNKPIFWIPGNHDFQPKMVEHLNKTPMESAKHLLLGKY
WQTLLLDSQVYGVPHGQLSQHQLNLLEEKLAQHPNRYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLGKFSNVKGILYGHIHQEVNALWNGYQVMATPATSIQFKPDSHHFTLDNLQP
GWREIELHENGSIYTQVKRIQEAQFLPNMQEEGY
>A0A4Q7I967|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio vulnificus|TrEMBL
MQHTSSDTLSENSIKLLQITDTHLFASDEGSLLSVKTLQSFQAVVEQVMARHVEFDYILA
TGDISQDHSAASYQRFADGIAPLEKACFWLPGNHDYKPNMSSVLPSPQITTPEQVALNPH
WQLILLDSQVVGVPHGRLSDQQLSMLEHYLQASPEKNTLILLHHHPLLVGSAWLDQHTLK
DAEAFWQIVERFPMVKGIVCGHVHQDMNVIHKGIRVMATPSTCVQFKPQSDDFALDTVSP
GWRELTLHANGEITTQVQRLASGSFLPDFTSSGY
>A0A1D3L4C4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methanobacterium congolense|TrEMBL
MQKKIIQISDIHFGEKTFSQDLKHNLLKQITDENPDLIVVSGDLTTEGYVHEYEDAATFV
DELRDITEAHIIPGNHDARNVGLMHFEKLIGERKFLHMDKKGGFAILGLDSSEPDINDGQ
IGYDQLEWLKTELGKIPSDMCKIVTFHHHLLPIPQTGRERNILLDSGDLLRVFADYGVDF
ILNGHKHVPNVWMIEKMVTLNSGTATTRKLRGQTYPSYNELLINDEGIHVNLVNTSTGYK
KELAEYTVKVEGDEYMICSYTHNSFYKP
>A0A8F9UXK9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas protegens|TrEMBL
MPSVSALTAADPVLLVQLSDSHLFAETDGTLLGMNTADSLQRVIDLVLAQQPRIDLMLAT
GDLSQDGTLESYQRFRQLTRQIAAPGRWLPGNHDEPQVMEQAASGSDLLDPVVDIGNWRI
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCLHHHPVSIDCAWMEPIGLRNAQ
ALFAVIDAFPQVRAVLWGHVHQEIDRLRGDVRLLASPSTCIQFEPLSDDFKVEEQVPGYR
WLRLLPDGRLETGVQRVEGYEFTIDYGSEGY
>A0A7R8NUA8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces sp. KY75|TrEMBL
MLLAQISDLHLDGSERATRRATRVMEYLRALPRPVDALLVTGDIADHAAEAEYEEAARIL
TAPFPVLACPGNHDARPAYRKAFLGEPPAATPVNRVHHIAGTAILMCDSTIPGRDEGRLD
AETLAWIDSTLGALPDGVPALIAFHQPPVELHHPLPDAGRLEEPERLAALLDAHPRVVAV
LTGHAHTAAASTFAGHPLIVGPAVTWTLRMPWEGDRPADRDQPPGLAFHVLGEDRRLTTH
FRVVL
>A0A3S5B3Y0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mannheimia haemolytica|TrEMBL
MHEYIKLPVTGVIKLLQITDPHLFSNPEETLLNVKTVKSFSAVIEQINKQAKQYFDLVLA
TGDLIQDHNIAGYHYFAQITNSLNSPIVWLEGNHDVQPSMSEILAQYKHILPHKQILLGE
QWQLLMLNTQVVGMPYGELSYSQLKWLEEKLAQYPQRFTLVALHHNILPTNSAWLDQHSL
KNSNELAEIFAKFKNVKAIVHGHIHQQVDDIWHGIPIYATPSTCIQFKPNCDQFTLDLQP
QGWREIELHENGTIETVVKRLNSNDFLPNVNAIGY
>A0A3L8BZP4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ketobacter sp|TrEMBL
MVSTTTQPSIRIIQLSDCHLFKSTEGKLLGLNTEQSLSLVMDLIKEEQPAIDLVLATGDL
SQDGSSESYARFHQWMASFTSPVYWLPGNHDLTDIMANHQAAKRMSPCVIDVGGWQVIML
DSTIRGKVPGNFADSELRFLEKSLQASQGKHVLIALHHQPVPVGSAWLDQQIVGNAAEFF
KVVDQFSNVRSIIWGHVHQVFETERKGVKLMSVPSTCVQFLPKSQDFAVDKESPGYRWID
LNADGSLDSGVSRVTGVDFVVDYSVKGY
>A0A2S7VBB9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio chagasii|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGES
WQMIMLDSQVVGVPHGRLSDQQLDLLEQKLAEYPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHSNVKAVLCGHVHQDMNREHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPNGQFLPDFEAAGY
>A0A7V7TG95|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio chagasii|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGER
WQMIMLDSQVVGVPHGRLSDQQLDLLEQKLAEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHSNVKAVLCGHVHQDMNREHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPNGQFLPDFEAAGY
>A0A4Q7AZY2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter bouvetii|TrEMBL
MPLSNHTDSSSGWTIVQISDTHLMDQDDLEFAAMNPEQSFHAVIQHMRQHLPDIDAIIHT
GDLAQVPVSETYDRYLRFMQTLNLPHFQIPGNHDDTAIFPFHRQKDRAHMLSFGNWRLIL
LNSAVEGKVDGWVAQEQLEQLDQMLSEQADQHIIIACHHHPFAMQSFWIDQHKLKNADHL
LDVIAKHQNVKAVLYGHVHQDSRNERHGVQFLSTPSTSVQFKPHSDSFALDESMPGYRVL
NLKENGEFSTHVIRVKTNQPKINVEISGY
>A0A2H5UX00|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|archaeon HR01|TrEMBL
MKLLQVSDIHGSVEMANRVAEMASKGFDAVLAAGDITHFGNTAQAEDILGRIGRAGVPVY
FVAGNCDPEILLSWRPRLENVFNIHLGREKLGGLELLGLGGGNTSPFNTIIEFTEDQFKD
MLASLNPSGRAILVSHTPPYGTAADFARGRHLGSKAIREYVERAKPLAVCCGHIHEGRAV
DSIGATKVVNAGPAKDGYCASISFSHDRLEVSLLRL
>O70286|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus musculus|TrEMBL
KTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLD
PMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFA
QVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWC
LDQLETLQTRHSVSEMASNKFKRMLNRELTHLS
>A0A4Y3INP1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio comitans NBRC 102076|TrEMBL
MERQIVEPQIVATEETVQLVQITDTHLFADDEGCLLSVNTGQSFVATVNDIVERNVEFDA
IVATGDISQDHSAASYSRFADGIKPLEKQCYWLPGNHDQKSNMVSVLPSPQIQEVGHVLA
GEYWQIIMLDSQVEGLPHGYLEAEQLELLDNKLTEFPQRHTLVLLHHNALPIGSAWLDQH
KLQRAHQFWEVLGRHQNVRAVLGGHVHQDFEKKHNGVRVLATPSTCIQFKANNDEFALDT
LSPGWRHLQLHKDGQLDSQVYRLEEGCFIPDFEAEGY
>A0A7C9L0G4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Agarivorans sp. B2Z047|TrEMBL
MNTAPDGSVHLLQVTDTHLFADEQTGLLGVNTNDSFSAVIENIKSDNIPFDYILATGDLS
QDHTKRSYQRFAERIAELERPCVWLPGNHDMQENMLTLEQHGVLAAKQLVSEHWQIIMLD
TQLEGEPHGIMSQRQLDNLAEALAEYPDKHVLIAMHHQAIPVGSKWLDQHNLKNADEFFA
VIADFPNVRGVIFGHVHQNYEFQFDGIAFIATPSTCIQFLPLSANFALDHQQPGWRYLQL
TAEGRIATRLRRLSERSFLPDPKSKGY
>A0A4Z0B697|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas nabeulensis|TrEMBL
MSSVSTLNPDAPALLVQLSDSHLFAEADGTLLGMNTRESLQRVIELVRVQQPRVDLMLAT
GDLSQDGTLESYQLFRDMTRQIDAPARWIPGNHDEPQIMAHAAVRSDFLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPSRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFSVSEQAPGYR
WLRLHADGRLETGVERVQGFEFTVDYGSNGY
>A0A7R8CWA0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lepeophtheirus salmonis|TrEMBL
MKQEVHSRSLLETFLVEDSFPGVLLRSCAVLEYITHCATHFWNDVGAREMGNLVPCGGTP
SNGRNGSSRRCSGSGRLLSANISGFSNRSSGDAKAGESLIPPASSIQGNSSSALGTIWRQ
SECINYRNFRLRRPKIRAIVALPKHSPQYNAAKWALERLGVESVLTFSTETAIQALNNGL
SSTPHLVLLDSRHPRNIDAEALAKHVRQSPYGNNIVVVGVVKKSFIEHEEVIVASHLRAG
FDRVLIDSGSRGYWMNELVLLLHNDVDTNIKLNCSESVLTALESCQDIVQITDKQNRLIY
GNPTAQKVLGFSQEELNNKCIWDYQSTKQNSNPISCDSSSSSSNNLLPTKSTLEPPLSDD
ADDVIKQKLDTGKVWEGPLNCRRKSGDYLALDTKIIPISFSSRRNSDHVIYVRKTPNLSV
PPIPSSSSAIVNNYNTMNNTKSSSCSNNTNNNHSNSSSCQISQHHLKHLSSTAHSSKALK
QQLHENHCTEVVSTSMASGNYYSGRRQSGSILPGMSIEAPITKIINIILSVQEKSPASIV
SELDKVIEILQATTGTTDLFSPELSKDGIKKRPDPVATDLLLELFYLSSIVYRQSIKVRS
TSVRGRNSTRDALTQRRGSTDPVAVSNTKNTSIHRTSLPNFDNSPVATRHLLENSSKWEF
NILELEKLTNKRCLVWLGMTVFFFDFKFTKLSIAQSPRFKIGLLLLKQITMQIFPITTLL
TLPMYFMQLPISLSLLESKSIVTVAFLCNSGNGLANLYNDITVLENHHASLGFKLTQSDK
RVNIFQNLDKDSYKLIRQGVIDLVLATDMSKHFVHVNKFASVFNTIESGECSVSDVVATD
GSDAVLSGVPNTPENVAILKRMLIKCADVANPARPLHICKVWAFRIAEEYFSQTDDEKRL
GLTVVMPQFDRATCSITKSQIGFYDFFINDMFDCLNNFDDFHKLVDIIQFNYNYWKQEAE
EEENAKDLQSEEEVKSSNRSKSASEKEDIREEDEDIPT
>A0A6G4ZS34|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chlamydiae bacterium|TrEMBL
MRIAHISDLHFGSASFSPMQFLSKRWLGNFNYFFHRKKEFLYNRLIDLINFFKEQGITHV
IITGDLSVTSRKKEFKMAKRYIDLLKKEGLSVFTIPGNHDHYTKRSDRKKHFYRFFDTHY
DKDCPFNLKQHKVTYTRLKEGLWLMGIDTTVATSLISSQGHFTPEVEENLTKALKEIPKH
EKVILLNHFPFFYNDVPKKHLVRGSLLKNLLQKHPNVQLYLHGHTHRQTVADLRGSDLPI
ISDSGSTPHIKNGACHLFDFGDNTIKLDVYRYEGEWKESESHTFET
>A0A6M1Z1I6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chlamydiae bacterium|TrEMBL
MTTPFRFAHISDLHFGSFSLSPLQFFSKRFVGNFNFLLNRRKAFAYNRLIDLIDLFKKEG
VTHIFITGDFSVTSRKIEFSMGKNYLDLLRKEGFTLFTVPGNHDHYTKRSHRKKTFYRFF
DKQFDPDCPLSLKKDLVTYTQLVQGLWVVALDTATATPLYSAEGHFSPEAEESLEKAFQA
IPKEDTILLMNHFPLFTTEKGKNSLVRAPLLKSLLAKNPNILLYLHGHSHRQAVADLRPN
QLPIISDCGSTPHRKEGACHLFTLEKTEISLDVYRFDDEWKKDHSHTFERA
>A0A151WXN6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trachymyrmex zeteki|TrEMBL
MLFPETGCCLGKLSATVAKRFYLPGGVVPDLVPNAKALDGKTDAFDIVTEKNEKTPFEDS
THDENGDYLTVKGPQDLSNYLLTTNVPSIVKILLVFSKDDQQMDILANIARRLGWNVSMA
KDAEKALELFQNRAHELVIIDHRAHHAAEGDAICRAIRSSPVYHNSVIIALVKKSYFMLD
EKDHIVALNLLETGFNRALMECSHESILINELVGIYTSSLLPRTQLAAAHALYLALDRCR
DMVHVTNDKNIVQFLNKVSEKLLGYKVEEMMGRNLSEIVYYENFPLMEQQLSKGREFEGN
MNCKRKNNQMITINCRIIPFCITLKKPSHYIYVYDTTYLSENSTPISPISSPLHPPLKTN
VTNARKSSDVRSGISEDKGRRRSSLQKLHTLQLEAPITKVITLLSNAVTDTTNPETAAQI
DKAIDILKTTELYVPHLKEDRAMCSDPVATDLVGALLASPRTAWESRRSSSDSARLSTIK
AITSPANSRVQVKNFRGPQEIMEILDKSLDWDFEIFKLEVLTERRPLVFLGLTIMNLYQV
PAILHCDERTLQNWLAIIEHNYNAENSYHNSTHAADVLQATARFMQSKRLKEILEPLDEV
AALIAAIAHDIDHPGRSSQFLCNANSRLAILYNDLSVLESHHAALTFKLSLSDDSVNIFK
NMERDAYKLLRQNVIDMILATEMTKHFEHLAKFMNVCSARIGDGQETYSDSLDMTVVLQP
DNVILVKRMMIKCADVSNPTRPLKRCVEWARRIAEEYFNQTDEEKKLKMPVVMPMFDRMT
CSIPKSQIGFVDYIINDMIEAWDVFIDMPEIVGYMRHNYEKWKEYNEQGISTLQDVEKLQ
QYPEMQILRLSQS
>A0A8D0H6Z4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sphenodon punctatus|TrEMBL
FPTAPLCSPGHLATHFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSD
SDYDLSPKTMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNK
>A0A5E4JDP6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKILAASDLHSDKKAAEKLAKKAKKNKVDLVVLCGDILEMGSDGNGLIGPFKKEGIEVLM
VHGNHDTPMDMDFLSEKYGKGVYNIHSYYKLFGDVAVLGAGGTSFGFIGSPDDDLFKSLK
VNFKKSKGKKTVLLTHEPPLDTKLDNIGWTNAGSADIRKIIETYKPDLVVCGHIHETFGL
TDYLGKTKIVNAGKSGVIIDI
>A0A5E4HEJ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKILHFTDPHLSAVGPIARIDNYEETCFRKLDEIRDIAKAEGAELILCSGDFFHLKNWMR
NPYSLVNKLIGYFKSLPCPVYGIIGDHDVPDRNESSVDRQPLGTLVSSGCLTLLSAGSMF
NSWNKVWITGAPKTDNYEADIKNYMPDMTKHHDNLIEGRPFNGVHIHMSHGDLYVKRPVY
EPYTLYSQLVGSPVDFHFNGHVHDDLGEVKVGKTTIINRGSLTRGSLVESNLNRKVTITL
LDTEKRALYYRELKSALPANKIFDLDKVRETKQAEAEINRLGELIKFESGNVELSGPESI
RHLVRELKTIREPVRTMIFNLLDKAEESV
>A0A5E4JV95|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKILAFTDLHANIIAYEKLKKKVKKFKPDIIFCLGDVSFFEQYLEQVLRKLNELKKPVFI
IHGNHETDTILKKLCQRYPYLIFAHNKVTSVGPYTIIAHGGGGFYTQGKSAKDKDFERLI
KNNKKKLRGKLILLTHAPPRKTKLDHISWAGHVGCESYAEFIRKYKPVIALSGHLHENFR
KQQKKGKTIICNPGPEGMVFSI
>A0A5E4KZD4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKLLALSDPHGDYSHIEAILEKAGSFDAVLIAGDLTNFGPDEQALELLKMFKEPVLAIPG
NCDNPSILKLLDEKGVNLHNSFRIIGDMVFIGVGGSNPTPFNTPFELSEKKIGEYIGTLL
SKLNDRKKFILLSHAPPRNTTDKLPRGNVGSEALARFLGRFDLIVCGHIHEARGSVHSNN
TLVVNPGVAARGQGALITIGDKISVEFIDAL
>A0A452QYH7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ursus americanus|TrEMBL
SFSFFHSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKS
MSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINK
ATITGKEDLVAFSSYV
>A0A508TQG0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bradyrhizobium ivorense|TrEMBL
MSTKPILIAQISDLHIKPLGALAYGRVDTAKALERCVATLNAFEPAPDFVVISGDLVDTP
TAEEYDHLKRLLAPLRLPFAGIPGNHDSRELMRAAFPAAPYVHAAGPLDQKIEVHGLDLL
LLDSSVPGKPHGTLETSTLQWLDTTLAAAIDRPALIFLHHPPFKGGIWHMDRQDLFNADE
LAGIVRRHPRAQLIGCGHVHRAMLTTFAGIPVTICPAPNHAVDLDLAQLRVPSFKVEPPA
FHVHAWFPGQELGQLVTHQVPIGQFDGPHPFFGPDGRLL
>A0A0A0FHP0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli G3/10|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A8C1C418|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyprinus carpio|TrEMBL
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQNDVEIPSPTP
KAREKKKKQLMTQISGVKKVSHGPSLNCGIARFGVKTDKEDLLSKELEDLNKWGLNIFTV
SEYSHNRPLTCIMYAIFQERDLLKTFKIPSDTFVTYMMTLEDHYHQDVAYHNSLHAADVA
QSTHILLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVL
ENHHLAVGFKLLQEDNCDIFQNLH
>A0A7C8LYB8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Halodesulfovibrio sp. MK-HDV|TrEMBL
MKNQNRRQFLQTGAFTLMGMSLMGRKAFAAPTKTDFAPVRFGVISDPHLDIKGKNGMKMS
AASVNCVGQAVKGLNQETGLSFVVVTGDLLLDGEKQNAEAIKELLDSLTVPYFVIAGNHD
FVPANPAKHRDGFDYLKIEEFVKFFDGKGYDGSGNRYWAHSVVPGLRVIGLDANLPLEQK
KWGGVLPQEQLNWLDKQLTDHKDEMNIVFMHHNVIPWSSDELKGGAKQWFCADNADAVRA
VLEKHAEAAPLMITGHRHIGMRVSELAGVNYMVAPSANTHPMRYSVLTVSPEAVTWKTPM
IGVPESVHIEARNNLLAATWWRETQYAERSATSDAEVLEFYEKNSQRIGTKVL
>A0A1A7ZD07|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothobranchius furzeri|TrEMBL
DWCLDQLETIQTHRSVSEMASNKFKRMLNRELSHLSEMSRSGNQVSEYISTTFLDKQNEV
EIPSPTLREREKPMCHISGVKKLTHSSSLSNSTLPRFGVKTEHEEALARELDDLNKWGLN
IFHVAEFSNNRPLSCIMFAIFQERDLLKTFRIPVDTFVTYVMTLEDHYHANVAYHNSLHA
ADVTQSTHVLLSSPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYND
ESVLENHHLAVGFKLLHEENCDIFQNLSKRQRQSLRKLVIDMVLATDMSKHMSLLADLKT
MVETKKVTSSGVLMLDHYTDRIQVLRNMVHCADLSNPTKPLPVYRQWTERIMEEFFRQGD
KERER
>A0A1B6H5V3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homalodisca liturata|TrEMBL
MGCTPSTHKKRGSRDDQSTHAHQLINSSGGSLRGVRGKRGSDGIIYHRSSGGDAGDSSGV
RRVWEWCVAASRCSLRRRAADAALVSTDDHDAQINELNADQTIEQQCHRLHQLNIPVPRP
QPIRVLLVFAKDDSTCNTLANAAEHLGLQRDIASTLDQALEFYQGQSSWPQIIFIDMRFS
WFKGDQICRSLRAVKRTHHIIFVGVCKKSAAEKDEKELRALLKIGINRVVVEPVSVVQAV
SELVQLGQGQVALHALLAQNEAIYLALDKSRDLVLVTDHSHIIQYVNRTWCQVFGYKVEE
LLAHSLPYFHQLGNMDQVTRQLERGFDWEGKISWRSKSGENITLQCRAMPYQAVGREPTH
YVYVQDNPLENHIYPRGSVPSIRKGSYDLKSINSEGAQSARRQSLAKLHNLPLEAPITRV
ISLICAAQENSTGQVVQILDKVVDILRTTELYSSHLKADNLRCEDPVTSDLIGALITQGP
VPVSTTRRSSNDSAAVKAAQALPPGAKAVFAMNASPQIKELLDSSLLWDFNIFRLEDLTG
KRPLVFLGMNLLLHFDVHKTLGCDEKTLYNWLTVIERHYHVTNTYHNSTHAADVLQSTAC
FLERERIKRLLDELDEACCLIAAACHDIDHPGKSSAFLANSSNELAILYNDVSVLESHHA
ALTFKLTLRDDRVNIFKGLERDTYKVARQSIIDMILATEMTKHFEHLAKFVSVFNKPNST
SDDGSGDAKSPSDCGGDFALTSSADEINLVRRMMIKCADVSNPTRPLKMCVEWARRIAEE
YFSQTDEEKA
>A0A6G1RV21|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hypotaenidia okinawae|TrEMBL
GERSGGRMMRERCGTSGGAGGGSGGPAMERLPPRQPDYMSVCLFAEEPYQKLAMETLEEL
DWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDV
EIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVKTEKEDHLAKELEDLN
KWGLNIFNVARYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYH
NSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTSEY
>A0A2P8ZNK9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Blattella germanica|TrEMBL
MFFSFQVCVETSCLSQCMNELLQLYTSDVEPRVQLATSQAVYLALDKSTDVVHITDENLN
IQYMNRSSERFLGYTIKDVFGKPLLDNNSVDNKELMVQQLQRGREWEGLITWKRKLGEAI
VLKRRQKSIDSTPSHFIFIHELPSSSHDKRISSAISKNPELPKSQNNRKGSVDMKSISSD
GLRRQSIAKLHNLSIEAPITRVIALITSVQESAPVVDILRTTELYSPQLKDDKGKPGDPI
TSDLMGALLSSGSTVAPIARRSSSDSGSVSRMGITSRTTFKSGHISIQMKELLDTSLLWD
FDIFKLEELSSKRPLVYLGMNLMNHFDVSSSLGVDESILYNWLTIIEINYNSKNSYHTST
HAADVMQATAGFLERERLKQILDPMDEAICLIAAAAHDLAVLYNDLCVLESHHAALAFKL
SMSDDRVNIFKSLERDVYKAVRQSIIDMILATEMTKHFEHLAKFVNVFSIKKEDDSPEGG
RSSPDTGILTAPENIALIKRMLIKCADVSNPTRPIRMCVEWAVRIAEEYFNQTDEEKANN
LPVVMPLFDRATCSIPKSQIGFMDFIINDMFETWEAFIEMPELLQNMEHNYAFWKEKERL
GIHRIPDVIIMQRSLRSGKTD
>A0A738XEG3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. arizonae serovar 48:z4,z24:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYGALQEAGISPAKHVLIGE
EWQILLLDSQVFGVPHGELSEFQLEWLERKLANAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSLLAHFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A7X1G7J9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas baltica|TrEMBL
MSSLSDPAVDAPVVLVQLSDSHLVAAADGAMFGLNTRRSLAQVVAQVLEEQPRIDLLVAT
GDLSQDGTLASYQAFAQATQVICAPTRWLPGNHDEPALMQQAAQGTQWLEPVADVGAWRV
TLLDSTIAGSAAGHLADDQLQLLERALAEAPHKHHLVCLHHHPVAIGSQWIEPIGLRNAG
ALFELLARFPQARGVLWGHVHQEIDRHAHGLRLLASPSTGIQFLPGSEDFALDNRAPGYR
WLRLMPDGQIETGVSRLANFTFTPDLDAAGY
>A0A6S7FE95|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter insolitus|TrEMBL
MTRILHFSDTHFGTERKPVVEAALDLARSLAPDLVVLSGDITQRARRGQFAAARKFIERL
SLPVLTVPGNHDIPLFNVFARALNPYGNYKRALGPVLEPVYENAGLLAIGVNTTRPRRRK
DGEISDGQIARVAERLRQAKPGQLRIVVAHHPVRAKVESDLSNLLNGRERALAAWTQAGV
DLILGGHIHLPYVLPLDPSAPSRGWIVQAGTTCSRRVRGNIPNSVNVITREEQGACHVER
WDYAAGAHAFAPVDRTQVGL
>G0QQY8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ichthyophthirius multifiliis (strain G5)|TrEMBL
MKFMKTQDENIIILDLLQVLIRLYIQEEDDESVISMLCRCRINPNTGLQKIQREDLEFYI
PQICNYIVFQQELKNQQMIEFLQTAGKVSIYFSHLLYFYLKSLTQIVSKKDFINFPLVEQ
MVNNIGKHFQEFYQNFKIETEQYDDLYKDYIQKYGTEQFINEQNKNNFINMNHIQLNNYE
KVIFFDENQQQDNSLNINSIQLSIKKQENNLLCNLQQNFEEEQEENIQNSDYFFSTINFF
EDLIKLSIEINKSNQKQTTLQQNIQKINKQLPANVYIPFFQDYIRNYVILNIVISECKIY
HTKDRAPIQLCVEVFRPDLEELYTEQQQKENIVNIKNLIQSVDIQIQEPLTVNVICLNFY
QKKKKKKKYKFLKKTYFFFFNIQRNIYKINKKIIKTNQLDIKVQLIKIYIYILIYILKNL
QIKQYKDSYNQKCYSTKNMKDKLNENPKLQNLKKIFFKYIRVQNLDISYQNQTQFMNENC
NNTNENSNNQIEDIKKLQTQFKQYADILFGQDVQKQEQIIKSQSIFQNLKTYKLIHFIVK
TGDNIKQEQFASQLINQFDQIFKDEGLNLQLLPYEIISLEPDSGIIKYVQNSVSIDKLKR
SLHENFKNVNNLFQFFQLYYGKNLKKAQENFCSSLAAYSLVCYFLQIKDRHNGNILLLKD
GHITHIDFGYLISNAPGKGLNFENNVPFKLINEYIEILGGVNSDMFKLYRKLFFKLKFNY
IIFYFQKRGFMAAKKNQDRILILAKMFYCGYGQSLPCFEKGEQAIEELEVRFNPQNIHND
GEYYIYTQNLINQSLDHWRARWYDKYQYFFEGIFY
>A0A178KQ31|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium jeanii|TrEMBL
MQTYTLPQQGPEKIVLLQITDTHLFDDESGSLLGVETKKSFHAVLNAVDDAARPFDAIIA
TGDISQDHSEHSYQRFADGIARWTQPCFWLPGNHDFQPSMRSVLPSPQIKACEQVLAGEH
WQVILLDSQVPGVPHGALSSNQLEMLDQALSAHPDRHALVLLHHHPLEAGSTWLDQHQLH
NNEALWYVLDQHPQVKAVLCGHIHQELDRVFRDVRVLATPSTCIQFLPDSHDFALDQANP
GWRYLELYANGDIQTQVYRLDGQQFAPQFDAAGY
>M3XNV4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mustela putorius furo|TrEMBL
MPSSSDLMSFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLS
PKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTVLTNLHGTSSKRSPAAASQPP
VSRVNPQGSNAIPTRLTRGSKCSFSTFLEGRTHRRLVFLVPLEICDK
>A0A5E6UZN2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEKDGTLLGMNTRDSLQKVIELVRLQQPRIDLIIAS
GDLSQDGTLESYQQFRDLTRQLDAPARWIPGNHDEPLIMAEAAVQSALLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDQDRNGVRLMASPSTCIQFEPGSEDFKVGDQAPGYR
WLRLLPDGQIETGVERVTGFDFQVDYGSDGY
>A0A5E7NKB5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTSADPALLVQLSDSHLFAEADGTLLGMKTRESLQRVIDLVLAQQAQIDLVLAT
GDISQDGTLQSYQAFRQLSAQISAPARWIPGNHDEPMVMAEAAVQSTLLEAVVDIGNWRV
TMLDSAVPGSVPGYLQDDQLQLLARALSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQVRAVLWGHVHQEIDRDRNGVRLMASPSTCIQFEPGSADFKVGEQAPGYR
WLRLLPDGKLETGVERVTDFEFTVDYGSNGY
>G9KFQ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mustela putorius furo|TrEMBL
FAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHS
VSEMASNKFKRMLNRELT
>A0A231H8L9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nocardia cerradoensis|TrEMBL
MTCCGPNRRRLLTALAVAAATPIVLPGSARAQADSLRATDLEVVTLTDTSAIITWTTLAA
DASGAPVPVEAGTEIRVAPADSAGPARTVPVTRTDRTPYHYAQIDGLEPGRRYRFEAWSD
GVRAVPAPELVTHLPGAPECSGEFTTLVAPPGRLLRTLALCNDVHIGEETSGIIAAGLPP
GVRQEPGLPPYPEVMLAAVLDDLRRPDRGADHLILAGDLTAEATPEQTRAVRNRLDAWGI
EGRDWFAARGNHDRPHTGADYAACPAVTADHYDCWGESFLPPAQSTEHRLGGLRLIGLDT
TELDGSGGSIGPEQFDRLRESLRRDPDRPTVVFGHHPVTAESGLTNLAGPNFVLNRSDAL
TLQQLYQSTPGVFFHHAGHTHRNRRTRPDIPLRVEFLEVGAVKEYPGGYTLLRLYEGGYM
VNFYKTRTPDARRWSTRSRAEYLGLMPEYTLGSTADRNHVVLGDLSGLS
>A0A0A1XJC2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Zeugodacus cucurbitae|TrEMBL
MRKCFVKISNAFRHKPVYAPPEPEHHNDAAEVEEHVRHSNAYADVEGALCGKGREASAAS
SDKTTTVKAKHSNNLASDKLKECNDKSADSADKASNSTNTTTTKTTKPIAKANRVDGNVN
EVYVGRAVQAREREKVVEKKKKKDKSKYFIRSATSPSLEEKTPDKHTCVGNAALLSTSDM
GDIAVYRSSQECGGMGDNRNSARSSTRSSGRSSGIFRLFLGSGKKKKKEKDDDSENEQEG
KREKKQEKVQERYKVSAEKAPLAVMEQQQLGFDEDELKALPKVSKTSGNAAAVRPRGGGG
DTDNIKTQLLDKPDDKSAYNKSNTYTYASAKGDLGDAADNETHRYRPNGSVDTKTESKVD
TKSTASVALTKTAKSHDERSYISEYKSFVEDEKPNLIGTPFPETEAFNFEQALNRKTSER
HSRVHTVEARTDTAKCHTETPKTPEEIEYEANMAAESADIMTPLPHNITFTSGRKSLTTA
RPLASDIAEMIRNLDANTLRINNMSVEEKIELMRRFEQPSQQEKEMDLKSAHHPHHQNHH
AHSSQQQQPTNNSLRRSSGSRNALNPLRLAMENRIVLQASTVGVTQQLQGVDIDGVGEST
CDSDDDVEVVLRRKYIDYPDGEKVIISSCLYERRQPEGPKLKLLVRSQQGDNRDEGSGER
SLMDVKFPTVLPPNPQLKALLVFHKSDNICEVITEACHRQQLDVTVARTKEGALDTLTNT
NEEFYHLIIIDARSTKHLDAEYIARSIRHTNGHHFTTIIAVVKKSFFEKDDVLIALLDAG
VNRCVPETTNLSMCNIELKQILHSIVRPHNVMSTQQALYTALHRLKEVILITDNHLRIQY
ANRAAERLLNMRMDEIISKPLADIFISDVSTIMIHGRKNKEFDEILTVRRKGQEDVAMHV
RVIPVACIGRTPTHYVFNLDVPGSHGDFVATLPQAREAPRGSQHSIRRGSVDVRSVASDG
LRRTSLAKLTSLPLEAPITKIINLLSQVQENCSPDEARLIDKVMEFLKREGLYSPQMKEI
RTDDPIATDLIGALLTGPSLYSSRRSSNDSIIRVGGRQSTCMPAKMKATPHIMELLEESL
SWEFDIFKLEEITEKRPLLYLGMEMFRRFNVFATLNIDENVCKSWLAVIEANYHANNSYH
NSTHAADVMQATGCFLTQLAAKDMGMDRTDEAIALIAAAAHDVDHPGRSSAFLCNSRNTL
ALLYNDLCVLESHHASITFRLTLSDDKVNIFKNLDTESYKSVRSVVIDMILATEMTRHFE
HLAKFVSIFGSDEEPKDIVQSEEESSILIRRMMIKVADVSNPSRQPSYCIEWARRIAEEY
FTQTDEEKAKTLPIVMPMFDRNTCSIPKSQIGFIEYIIQDMMHAWDSFIDMPQLVTYMQI
NYSQWKKFEDQGVHTLADVKSKQHSLSVKKSAK
>G7LPB9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Brenneria sp. EniD312|TrEMBL
MESLLTLPVAHGARIRILQITDTHLFAGEHETLLGINTYRSYHAVLDAIQAQQYAFDLIV
ATGDLAQDHSLEAYRHFSRGIRRLSAPCVWLPGNHDFQPAMVDALAEAGIAPSKHVLLGD
KWQTILLDSQVFGVPHGELSDYQLEWLERTLQSQPDRYTLLLLHHHPHPSGCNWLDQHSL
RNAHSLAAILARYPRVNTILCGHIHQELDLGWHGRRLLATPSTCVQFKPHCTSFAIDDVA
PGWRYLDLMPDGQLETEVFRLQGNEFLPDMNSDGY
>A0A8D2KCC6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Urocitellus parryii|TrEMBL
MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAEPERP
PHRPIERADAVDTSDRPGLRTTRMSWPSSFHGTGTSGGGAGGGSCRRFEGENGPTPSPGR
SPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSXNSSVTSEAHLYLLPPPF
QVLASLRSVRSNFSLLTNVPIPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDWCL
EQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPS
PTMKERGPQEAPXQRPSQQPLPLGPQFQPMSQITGVKKLMHSRSPNTSVPRFGVKTDQED
LLAQELENLSKWGLNIFCVSDYAGGRSLSCIMYTIFQERDLLKKFHIPVDTMKVTSSGVL
LLDNYADRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMC
DKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSEGGAEAPEGG
VPTLLYYTYCTIVPGKGALCNFMGSCVIIGARAGQSLPPAPSPGAGVTGKRPPTQSGWV
>A0A250BHD3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Brenneria goodwinii|TrEMBL
MESLLTLPVASGARIRILQITDTHLFAGEHETLLGVNTYRSYHSVLNAIQAQQYAFDLIV
ATGDLAQDHSLEAYRHFSRGIRQLSAPCVWLPGNHDFQPAMFDTLDEEGIEPSKHVLLGD
KWQIILLDSQVFGVPHGELSDYQLDWLERSLQSQPDRFTLLLLHHHPHPSGCNWLDQHSL
RNAHNLAAVLDRYPLVNTVLCGHIHQELDLEWHGKRLLATPSTCVQFKPHCTNFAIDDVA
PGWRYLDLMPDGRLETEVFRLAGSEFLPDMDSDGY
>A0A366AE84|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio paracholerae|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFAAEDGSLLSVNTADSFAAVVAAIGEEQVEFDAILATG
DISQDHTPESYQRFVRGIQPLKKACYWLPGNHDYKPSMHSVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEYPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRIHLGARVMATPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A7W2ZA48|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. RHBSTW-00325|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRAKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A7L6BN55|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. RHBSTW-01013|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRAKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A1Q9NWL2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Thorarchaeota archaeon (strain AB_25)|TrEMBL
MEPQRYALAVVVILVVASMSIIGLYQILGPEDDSVLNFYVFGDSQGYQDGILEIAEIANQ
ERPDFVFHCGDLTPFGQSNQYEEVISALDTFTVPVYTTVGNHDIHGGGGARYLQHFGPST
YSFDSEPIHFTIFNTSTNDVSETEMTWLENDLSQSSSEIKFVFTHTPPFDPRTGSDHGML
NETMAERLMALFEAQGVNTVFTGHIHMYNESVKNGVRYVITGGAGASLYADEEEGGIYHF
VNVTLAETGVEIVPVLLAPPTLERDRVVVRGTDADVTLSLSDLIGMDMTEGWSSFQNQFD
NWRGYGLYTGVRVSDMVGLVGGMGVSDTVRVTSFDGYSQDFAYGNVYPNTSWYDIQGDMI
LAYELNGTEVLDWTDGMRLVMLPTDEAYSNNDCLATSAPGMGYHVYPSAGARWVRFVSFI
EVIPG
>A0A022PLP6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus aegyptia|TrEMBL
MESQFELPVVEGTTAKILQITDTHLFASKEDTLLGINTYRSYQAVLDAVLKQNADIDLIV
ATGDLVQDQSLEAYRHFADGIVRLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGK
HWQLLMLDSQVQGVPHGELSEYQLEWMKKCLDQYPERYTVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQGYSRVKAMLCGHIHQEMDMDWNGIRMMATPSTSVQFKPHCTNFTLDTVA
PGWRYLELSISDRGEFGLTTQVHRLESNEFCPDLDSDGY
>A0A8D2F8S9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Theropithecus gelada|TrEMBL
MAQQTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISP
RNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSTGRSPLDPMTSPGSGLILQANFVH
SQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALT
NLQDRAPSKRSPMCNQPSINKATITGSWMELNPYTLLDM
>A0A135I4J3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterovibrio coralii|TrEMBL
MRICHLPKQHNQTVRLLQITDTHLFADHAGSLLGVNTCASFNAVVNEIVKEGVDFDAIIA
TGDLSQDHTAESYQRFVDGIARWSQPCYWLPGNHDYQQEMKKVLEQSTLERCEHVLVGEH
WQLIMLDSQVPGVPHGRLSGEQLALLENTLRDNPERHTLILLHHHPLPAGSAWLDQHKLH
NQDEFWAVVAKYDTVKGVVCGHIHQALDTQHQERRVMAAPSTCIQFQPNSDDFALDLTNP
GWREIALHADGTISTTVGRLKGNEFQPDMTSSGY
>A0A2P5VL50|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alphaproteobacteria bacterium MarineAlpha1_Bin1|TrEMBL
MRFVHLTDMHITADNQPLYGLPPGDRLQAAVDCINQDFTDIAFVVMTGDLVNRGTAPEYQ
YLREIVNSLNAPYYLLLGNHDGRSAFREIFPEVRVDNNGFVQFTFTVEDNYFIVLDTLDE
GKVTGLLCRQRLDWLQTQLKACNGRDTYLFLHHPPLRLEGGLELAEMIFGKVKHLFFGHL
HRPLHGSWRGIPITSQFSTLHQFVYKFGSKVMQGCHEPPTLGAVNLADGNVVVNPHAFLD
DSPRFNLRSKVAMKASSPEELPPLDS
>A0A2P5VJA0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alphaproteobacteria bacterium MarineAlpha1_Bin1|TrEMBL
MFLVQISDTHIDEPGRLVYGHFDTAAALEKAIDAINAMKPGPDLVLHTGDIASHGSLRRY
EAFGAIADRLTAPMVLIPGNHDDRGALREVFGGTSWLPATSDFLHYVIEDHPVRIICCDS
VIAGETSGEMCPERLAWLDARLREAPDRPTIVAMHHPPFYSGMTGSSSKGLRHGGAELDA
LFRRHGQVVRVLAGHVHRPITASFGGTIAFAGPTTCYPFDLYTGPDRLLNISYEPPAIAV
HLWLEDAAPSGPGLVSHTMPVGDWLPPLTLLRAGVKVLDV
>A0A644XF80|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKTPIFMTSSKQHFRLLVSFVGMLILSCTHSFAQSDSTVIVQITDTQFGFFENNTGFEKE
TELYTKAVRRINELKPDFVVITGDFVNDSKNILQIGEFKRITSLIHQNVPVYLSPGNHDL
GQSPTKNDFNFYFSNYGRGTDRFSFKHKNLAFIGLNSVIVKSNKNKKEEKKQFRWLRNQL
RKAKKSGSIVLFTHYPFFLYDFNEKETYSNQSVEVRDRYFQLFERYGVDAIFAGHLHNNA
EASHNGISMITTNAVGKPLGNAEPGMRIITITSEGIKSRYISIE
>A0A644T8G5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MHSFIYFRTRWLISLLLLLWCGFSAAQNSAVLKFRQGEPFKIVQFTDVHWDNTQPNCAET
ASVIKHVLAAEKPDLIILTGDIVTYSPAAEGWDAIAAIMSESGIPWAVTLGNHDDEPGLS
RSEIFDLLEPKKGFIGQKGPEEISGTGNYILEIKASDSDKTSALIYCIDSHSYPEEKKLG
SYDWVRFDQIEWYRKQSRKFTEANGGNPLPALAYFHIPTPEYKEVYDSKSSLGEKNEGVA
SPLLNSGLITSMIEMGDVMGTFTGHDHENNYIALYHSLALAYGQVTGVNAYGKFERGARV
VEISEGAHSFNTWIRTNSGVSFPYNFPFGGTYDESAYDFLKAEQLSDMKPGISYSYFEGT
FKSTDDFAGVEPVHRGVVQEITLEPRQAEDHFGFEFNAWIEIPEKGLYRFSTWSDDGSRL
YIGGKLVVDNDGSHSARLKEGAIALEKGFHRFRLLYFDDYMGETLEAGISGLTFREKPVT
GAMLFIPENKNKSNPQK
>A0A644TV69|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MSNAILHISDLHFVLDKEERKDKTRFDNNFQQKFLDSLKENKNNTIKYLVVTGDISDTAA
EKEYSKAMSFLEIVASDLQIEKKNIIICPGNHDISRTELAIIAENEDIEDSQLYTKQKEK
FAHFTKFYSDFFKGIKPSFDVNSAIFDKIIDHDDRIVILAVNTCFRESNQDKDHIGFINK
SSFETELNNIDFQNQYKDYGKILAMHHNPKDLSSEKKHNLENWKELPKDNIGLPFIVLCG
HIHGQDGEATQRNDGSIAYISTGSLTKNTTENTFNIYYDIGESKINIDYYALQSKDNLAK
SFWQSLTNINQQLKTADFRPNLNESTLKLDEVDILLNEVDEGMKQDINRELQKPKKHQTT
KHLNKITNRNIIDFIKERNLFKSGHFHWKNEFRSHGFIDINNLVSRKDSLEVITKLFYNE
ICKKFNNKFQDTIIIAVGIECNIIGARLSILLDCGYSYIPEPSKEKDFSEIEKTIKSENY
KKIILLKDIVYNAEHSKELLTAINTDNKEIFVFSLFYCGKKEMKESIFSNYNNVIFVSIC
DDIAINQCDYSGKGCLDKCPIYKNKLETIYDEC
>A0A644U4B9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MAFRFVHTADLHLDSPLVSLALRDPVLAAEVGTATRTALSRIVDLCLTEAVDALLIAGDL
WDGAQGSAKTPRFLRQELARLGAAGTRCFIIRGNHDAMSKVTRELEPPPGTHVFGGRAAT
EVFEAAGRTIAVHGLSFAQDSAAESLLPRYPAPVPGAINIGMMHTSLNGSPGHDNYAPCA
VADLDAQGYDYWALGHIHRRAEYRGRSVVVMPGMPQGRDIGESGEKTVTLVTVTDDGTVT
TEARAVAPLRFERVGLDLSGIADWAALPGRLAAALRDAAGAAAGTALVLRPVLVGTTPLA
WRIGRDLDRLTEEARAAAEAIGGVWIDKLEARVSGGDVQAGRLPADLLRLLNDDLPGDAG
LAAQLRKTAEELLHDLPPELRGLLGEDEAALEAGCAALLATGTAQLLARLAPGGEEG
>A0A644VZ98|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MRLYTFAFIILLLSIVLPDLFFYFKLKKHRAKLILHLLNFLPTAFFITIFAIMKFADSHS
YQPSSFQFFMWMNFVFMVIYLPKLVYIIFHFLNFLINLLLKEKIYLIRYAGVLTGMFLVI
LFAHGAFVNPKNIDVRQTEIKVSGLPPTFDGYKIVQISDIHLGSWGRNYSYMEPAIKKIN
EQQADLLLFTGDIVNNYSQEMDGWDKYFQQLEAKDGKYAVLGNHDYGDYSEWEKEEDKAA
NLTAIQQHIRNFGFKLLSNEFVQLQKDSGIIELLGVGNWGKPPFPQYGDLNQALAETDST
TLKILMSHDPSHWKGEILGHKNIFLTLSGHTHAAQMAFNMYGKLISPSSLIYDEWDGLYQ
EGEQYLYVNRGLGFIGIPVRLGVARPEVTVITLRTKK
>A0A645AYT4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKSFFLTILFFYVTANVYAAIRIYQLIPANAWVRIVVMGIFLLGFASLLIFFRFGEAMPV
GTAGFFYRFGTSWMIAFLYVFMLILFVDLFRIINWVAPIADKETVRGIFHHNALTAVTGL
GLTALILLYGNWQYHNKKRSHITIKTEKIDKPMRIVGISDLHLGYTISKKELSRWVEMIN
AENPDMVIIGGDLVDNQLRPVWMHSLDRELLKIKAPLGVYACTGNHEYISGIKNSADFYT
RSGITLLRDSVLQTNGLTIIGREDHSRKNRKTLPELIKNSDNRTFSILLNHQPYYLDEAV
REGIDFQFSGHTHRGQVFPASLITDKIFELSQGYIQKKNTHFYVSSGLGIWGGKFRIGTR
SEYLVLDLEN
>A0A644Z1B9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKFDFRIFLFVLVATVVYILGNYYIGRRVMERIQYKYTVNTKMFWTVFWIIAFAYIVNQI
AGSYLPRFVSTPILYIGIYYMAIVSYLMLIFPIIDTIRFANKKYAFLPKDSTVYSSFSFY
ITIFMAVALTGILVYGTWSGRSTYVKPYDVNVNKALKENNLKIALISDIHLGDYMDVKRL
QNLVSEVNKINPDIVLIAGDLIDSSIKPFVENQMAKELGQLSSKYGTYFSFGNHDLGNKV
PQLTSLLEEVGITVLKDEYKLINDSFYVVGRQDVAIKRTGGSRKYLSEITEGIDKSKPVI
VIDHNPMNASVKEAQEEKIDLQVSGHTHRGQFVPYNFFTNRGYDYVYGYDRMEDFNVVVS
SGYGTWGPPIRIGSRSEIVQINLTSNMELVDKGGSR
>A0A345P3G9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aquirhabdus parva|TrEMBL
MKSEYLIVSPLIQLDWDTKKPIDGDTHLNAGVLSISTADPSKPIRVVQISDTHLFEDTSA
KLLGMNTEDSFQAVISLIKKEQFQKEISSDHLNTRFSTDVELFLTTGDTAQSPAQATYKR
FLDVMGTLNRPCVWLQGNHDLGELLKDSTDCSSINIVELGTHWVILMLNSAKDHEISGQF
TTQELNWLKTTLARYPDRHVIIALHHHPISVSSTWLDESGLLNAQAFWAIVDDAPQVSLV
IHGHVHQEFEAKRGSVQVLACPSTCIQFKPLSEAFTIDKLPPGYRWFNLYANGKIETGVS
RLKKLPAGVDFNSQGY
>A0A857EGS2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia rhizosphaerae|TrEMBL
MESLFKLPVASGAKVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAVRAQQREFDLVV
ATGDLAQDHTPEAYRHFADGISQLPAPCVWLPGNHDFQPAMVDALAAAGITPSKHVLLGE
HWQVILLDSQVFGVPHGELSEYQLEWMERCLQAHPDRYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAILLRYPKVNTLLCGHIHQELDLAWQGRRLLASPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVCRLDNDDFRPDMDSDGY
>A0A5H6BRX2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella potsdam|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADVPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A4Q8PCL9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Brancaster|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A7R9R8I9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Methanoperedenaceae archaeon GB50|TrEMBL
MRILHTADLHLGRTGKDRDIWHQWEKIIEIALKENIHILLIAGDVFDNGQAEAVLKKKFV
ISLNKLANQGIQIFIIPGNHDLRQGNALTDLELPGVNVFYKYTVVNLDKIALHFFPFKPE
LSGQDLVGLKQDSGAECQIGVCHASYITLPEVFSDLGDSQAIHCPLSPEDIRDLNLDYLA
LGHYHNPKQWQVGKTQCVYPGSIEPLSFKEIGPRQVFIIQYDHGLRVYPIEIGYQRPYLC
QDIQIPKEDIHALWPKIEELAQDFGPCFLRLTIKGVADKLLFQAFQLKAEAFLKERAIEV
SWQDETVDLGWIEENRLAKQFKEAVQHRVRQSPEKEFWWQVLYRGISLLKHCENVDKKNK
V
>A0A7J0A277|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacteroides acidifaciens|TrEMBL
MIRLLRFRLTLILLLATTFCIAQKRELKFSKDGKFKIVQFTDVHFKYGNPASDVALERIN
QVLDAERPDLVVFTGDVIYAAPADSGMRKVLEQVAKHKLPFVVTFGNHDDEQGLTRSQLY
DIIRTVPGNLLPDRGTALSPDYVLTVKSSSDSKKDAALLYCMDSHSYSPLKDVKGYNWLT
FDQINWYRQQSAAYKAQNGGQPLPSLAFFHIPLPEYHEAIRDENAAFRGTRMEEACAPRI
NTGMFAAMKEAGDVMGIFVGHDHDNDYAVMWKNILLAYGRYTGGNTVYNHLPNGARIIVL
DEGARTFTSWIRQKDGIVDKVSYPASFVKDDWTKR
>A0A5W2LM94|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Lattenkamp|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A4P7IMI3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas hydrophila|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VILLDTQVRGKPHGVLGDHQLAALDQVLRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRIASQVWRLPVGQFVPDPNATGY
>A0A0T9MGS3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia intermedia|TrEMBL
MESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTSHSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGISRLPAPCVWLPGNHDFQPAMVDALADSGIAPSKQVLVGD
NWQILLLDSQVFGVPYGELSDYQLEWMERCLVAYPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLVRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGILETEIRRLASDEFRPDMDSDGY
>A0A8G6J533|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas aeruginosa|TrEMBL
MSRHSNTPATDASVLLVQLSDSHLFAEDGARLLGMDTAHSLEKVVERVAREQPRIDLILA
TGDVSQDGSLDSYTRFRRLSSPLDAPLRWLAGNHDEREPMQRATEGSDLLEQVVDVGNWR
VVLLDSSIPGAVPGYLEEDQLELLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGY
RWLRLHDDGRLETGISRVDDVVFEVDYDTAGY
>A0A5H6JAL1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Napoli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A183IBC2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Soboliphyme baturini|TrEMBL
MENFDFVTVNVFSDIDSMVKMFTVPSPKLSTKDDPSLWLALLVTHTRDPFIGKVEQSLQA
SNWQCWTCKPDEEQFMESLLTLMPSVLLVDLRGRKTKEQWNKLKLSLLERRGLRYQQYHR
LCNALSIALDHCESAIEICDHENHVLFVNNAYEQLTGCSRKEVLGTESSDLRRKSLPKNK
LKLTNQDSKSSASEWKFVPADQHLENYLLGLFSHKIFLKRVEMDMKSMKVQSDFRLPPIT
ILKKLVEAPLSQSNILKVVDLLQNVQKTSTLDEEVQNTIQKIVKILKSTELYSPLIPRFS
YEDKIASDLFSGLVMNGPQKISANQRRTSLYEVMQNEKKKSSESHVLDADVRTDLKSLEW
NFDVFTLEKLTMKRYGTNFKYNKYKCLNVRRRPLATLVMEIFQQWNVHEFLDCSLSCLDR
WIQAIEANYHAENPYHNSTHAADVLQATAYFLSTPFLSNIIEHSDAVASLLAAAIHDVDH
PGKTSTFLINTNHPLALMYNDLSVLENHHVAFAFNLTLTNTDLNIFSQLSRDAYISLRKR
IVDMVLATDMMKHFEYLSKFKQTVLESGVFYNYNISSFFQEMSSRAEASSKLLNSVDPRR
TVCQMLIKVADVSNPIRPWKFCKKWAYRIVEEYCNQTDEERAKSLPLTMEVFDRNTCNIP
LTQCRFTDMFIREMMELWCRKNRFLSSQTMEIVRAF
>A0A4P9T764|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A729PV66|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae serovar 48:d:z6|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGD
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A2X4TLG8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. arizonae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYGALQEAGISPAKHVLIGE
EWQILLLDSQVFGVPHGELSEFQLEWLERKLANAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSLLAHFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A137PLK3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lactobacillus johnsonii|TrEMBL
MLTQDKKTSFWVISDTHLIADSLHDHGQAFSQMQKTSQGKDLYYQETALSAFVRMAQKKK
PAAIVVTGDVTFNGERVSAEKFAEIFKPLEETQLLVLPGNHDIYDGWAREFRGKKQYYAG
QISPRMWRNIFKTSYKNAVSVDDESLAYSVQLNPDYLLILADSNDYGKEEATTAPATAGF
LGREQRRWIKAQLQYASENNLQVIFCMHHNLYAHNPAVNKGYVVDDYRELRKLLAQYNVK
LVFSGHIHAQNIMLPQDPCPATEVVTASFCSNDQCYGVVKVSPKEVSYTCHHFKMKDYLT
DKEKQNWTLTHFHDYLENIQLGTISAELMQKNLYQNHDDLDTVRKMGRLFGEMNYHFFTG
KNHIESEELQKLKKSPIYQRLIAESPHYELYLQTLYDTSAHDNLHVKIKY
>A0A2V1YHS5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter agglomerans|TrEMBL
MDSLLTLPAANGSEIRILQITDTHLFAGKHESLLGVNTWSSYKAVLDAIIAQHRDYDLII
ATGDLAQDHSIEAYQHFAEGISRLPRPCVWLPGNHDFQPAMFDTLAAAHINAHKQVLVGE
QWQIVLLDSQVSGVPHGMLSDYQLEWLDNALARYPQRHTLVLLHHHPLASGCTWLDQHSL
RNSHQLDAVLQHYPLARTLVCGHIHQELDLEWHGRRVLATPSTCVQFKPHCTSFTIDTVA
PGWRWFTLYPDGGLETEVNRLDTDAFRPDLDSEGY
>A0A2S7VUN5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio jasicida|TrEMBL
MQSSSDSIKLIQITDTHLFAADEGSLLSVRTADSFEAVVKEVLHRQVQFEYILATGDISQ
DHSAESYQRFAEGIAPLEKACFWLPGNHDFKPNMGTVLPSPQIQSVEHLLLGEHWQLILL
DSQVVGVPHGRLSDQQLSLLEEKLSDYPDRHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFENVKGILCGHVHQDMNVLYNGIRVMATPSTCVQFKPNSDDFALDTECPGWRELE
LHPSGDISTEVNRLTDGQFQPDFTSNGY
>A0A0L6ZW35|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLAKFPNVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A0T6UGR0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas allosaccharophila|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQANEHPYEVILAT
GDLSQDHSPESYQRFASMMAPLGRPIYWLPGNHDDSPLMTEYLHAAGISESKQLVGDHWQ
VILLDTQVRGKPHGMIGDHQLAALDRALRQYPDRHALITLHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLCDGFALDESGPGW
RYLTLYPDGRVASEVWRLPVGQFVPDPDATGY
>A0A0K8SGT4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lygus hesperus|TrEMBL
MGCNHSRKATFKSISAQNLQTPDKKDKKEEKVKTPILNMKMVVGTVASNPDQLLPEMYES
LLKMESIQSSIALSKSVFAVLEKCRELVMITDNNNCIQYVNTPMARVLSHTPSELTGQIA
TVFQEHSDLQPAIRTLERGFEWVGRIRWRTKSGDSVSLQCRSMPISPAPSYPTYYLYLLD
SPSDCHFPRGSVPSLRKGSYDLKSIISEGSARRQSLAKLHNLPLEAPITKVLSLLCAAQE
NAPPNVIGMLEEVMDLLRTTELYTSHLKTDNLRAEDPLTTNLIAALVAKGPPSSIMPRRS
SAESPTKKKLMYKKNTNVVLPASKELKEAMKKINTWEFDVILVEKLTSGKPLVYVGIKIF
SIFNAYKVLGVDEKTLYSWLVLMVNHYIPDNSYHNSTHAADVLQAAACFLLKLRSKKLLE
PLDEICCLIAAVAHDLGHPGKSSAFLTNAGDDLALLYNDISVLEQHHASLTFRLTLADDR
VNILRGLEQSKYSTARSCIIDTILATDMYKHFEHFTKFVTIYSKSSEDVPEKNEKPGESE
VDVNPEDVVVVKRMLIKCSDVANPTRPLQLCKHWAKRIAEEYFTQTDEEKERNLPVVMPL
FDRSTCSIPISQMGFMDYIVNNMFEEWDAFLEMPETLYNLRKNYDYWKDLNDKGCVGIEE
ETNGKKEVQDSAQI
>A0A715RU16|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Typhi str. CT18|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPVMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A344SKL9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A748ET46|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella typhi|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPCVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A708DZE0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella typhimurium|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A5X3NE65|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Poona|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A701SDR0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella muenchen|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLLDTRFRPDTASEGY
>A0A5W3IHC3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella muenchen|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGALSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A4SIH1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas salmonicida (strain A449)|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQVNEHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VMLLDTQVRGKPHGVLGDHQLAALDSALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRVASQVWRLPVGQFVPDPDATGY
>A0A0S2SHJ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas schubertii|TrEMBL
MRLLQITDTHLFANPEGQLLGVRTADSLAAVLERVQGSDEPFDLVLATGDLSQDHSAGSY
QRFAQMMAPLGKPIYWLPGNHDDGPLMNQSLFEAGISEAKWLVGEHWQIILLDTQVRTKP
HGVLADHQLAALDRALRTHPDKHALIALHHQGVPVGCAWLDQHNLKNADDMFAVLARYPQ
ASAILFGHVHQEFDEVHRGVRLIATPSTCIQFKPLCDDFTLDESGPGWRYLTLHPDGRID
TQVWRLPAGSFVPDSQARGY
>A0A5E4ZBQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea aquatica|TrEMBL
MSQSSQTSQTSQTSDVPPGASHTHGKSSKRTLPARPRWLMLAIIALLHAYIGWRLLTPLP
VAMGWKVLGGLWLAVSTVLIPLGLMSRAIQKEPLATLLTWTGMTAIGIFSSLFVLTLLRD
VVLGVAMAFSVLDAQLVTRSAVIVLILTAASTVLGFYNARRLARVVEIDIPIADLPSELK
GFTIVQLSDIHVSSTIRRRYIEAIVEASNALKPDLVAITGDLVDGGVPALRDHIAPLGQL
TSRHGTYVCTGNHEYYSGAPAWVAELRRIGLTVLENEHVVLDHEGAALTVAGVTDFTAHQ
FDPEKRSDPQAAIAGAPEGVPRVLLAHQPRSAPAAQEAGFDLQLSGHTHGGQFWPWMYFV
PLQQPFVHGLHRLGRLAIYVSRGTGYWGPPKRFGAPSEITRIRLVPGKV
>Q4RBU3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Tetraodon nigroviridis|TrEMBL
QFKRMLNRELSHLSEMSRSGNQVSEYISTTFLGKADMPSPL
>A0A4R0XSE0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. ANC 4862|TrEMBL
MTLSDYNETQQDWTIIQISDTHLMNQEDLEFAHMNPEQSFHAVMKQIQQQYPNVDVIIHT
GDLAQVPVKETYSRYLAFMQRLGIPFYQIPGNHDDMDLFPFYHNQNQVHAIHFGPWSMVL
LNSAVRGKIDGWIEEEQLQQLDRILSKFQQQFVIVACHHHPFDMQSKWIDQHKLKNTENL
TDILAKHSNVKAVISGHVHQDALNEWKNIQFFSTPSTCVQFKPLSDDFALDEEAPGFRVL
HLKANGELQTEIYRTEKAQQKINVEISGY
>A0A380TRZ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|[Actinobacillus] rossii|TrEMBL
MVNTYIDNRQAEIIRLVQVTDPHLFKEENGELLGINTLASFNQVLSEIQETDFAFDVVLA
TGDLVQDSSDEGYLRFCERINTLNKPVFWLPGNHDFQPKMEEYLNEKYGNINSRKHLLLG
DKWQVLMLDSQVFGVPHGNLGQYQIDWLMAKLKENPERYTLVVLHHHILSTNSLWLDQHN
LRNSEELAQTLAPFRNVKGILHGHIHQQMDAEWHGYKLMSTPSTCVQFKPDCNTFTLDSL
QPGWREIELHSNGEIITRVKRIQHAEFLPNMHEEGY
>A0A7W4F4L7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia sp. OS31|TrEMBL
MESLFKPTVASGARVRILQITDTHLFAGENETLLGINTYRSYHAVLDAILAQQRDFDLVV
ATGDLAQDHSLAAYRHFAEGIARLPAPCVWLPGNHDFQPAMVDALADAGITPSKQVLVGD
HWQVLLLDSQVFGVPHGELSEYQLEWMERCLQAYPERYTLMLLHHHPLPSGCTWLDQHSL
RNPHMLGAVLLRYPKVNTLLCGHIHQELDLEWQGRRLLASPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRIETQVFRLENDDFRPDMDSDGY
>A0A2T4N5N3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas veronii|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQANEHPYEVILAT
GDLSQDHSPESYQRFASMMAPLGRPIYWLPGNHDDSPLMTEYLHAAGISESKQLVGDHWQ
VILLDTQVRGKPHGMIGDHQLAALDRALRQYPDRHALITQHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRVASEVWRLPVGQFVPDPNATGY
>A0A2X1SZK8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Morganella morganii|TrEMBL
MEIPLHLPVADGAAVRILQITDTHLFAGETDTLLGINTLNSYHAVLDAIAKQQLPADLIA
ATGDLVQDQTIRAYQRFTDGIARLPAPCVWLPGNHDYQPSMAKELAAAGISSSKQVLLGE
QWQILLLDSQVQGVPHGELSDDQLIWLDNCLAQQPGRHTVVMLHHHPLASGCTWLDQHSL
RNSHMLAEVLTRYQNIDAILCGHIHQDMDFMWNGIRILATPSTCVQFKPHCTNFTLDTAA
PGWRYLELTTGDNPSLSTQLFRLETDEFSPDLGSDGY
>D2C247|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dickeya zeae (strain Ech586)|TrEMBL
MESLLTLPVASGARVRILQITDTHLFADEQGTLLGVNTNRSYQAVLNAIAAQQMNVDLIT
ATGDLAQDHTQDAYTHFATGIRRLGAPCVWLPGNHDFQPAMVDVLARSGIAPSKHVLLGE
HWQVILLDSQVFGVPHGELSEYQLEWLERSLQSQPERYTLLMLHHHPLSSGCTWLDQHSL
RNAHSLDALLSRFPRVRTVLCGHIHQEMDLDWNGRRLLATPSTCVQFKPHCTNFTIDNVA
PGWRYLELLPDGGVETRVCRLEGNEFLPDMDSEGY
>I4SPP6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli 541-15|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A6M8FCW3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas campi|TrEMBL
MPAKRGKCDPFTFAGFTESHFSHHNPENLFRSRTLSRPVSLAHDPSVLIVQLSDSHLFAE
EDGKLLGMNTCDSLQRVIERAREEQPHIDLMLASGDLSQDGSLASYQRFRELTDPVAAKA
RWFAGNHDELPSMRAACKDSDRLEPILDLGNWRITLLDSSIPGAVPGFLGDDQLELLEQS
LNAAPERHHLVCFHHHPVSIGCTWMEPIGLRNPDALFAVLAKAPQIKAILWGHIHQEFDQ
QRDGVRLLASPSTCVQFAPGSEEFQVDTTAPGYRWLRLHADGRLETGVSRVTGIHFEVDY
SVKGY
>A0A061QA53|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. JCM 19052|TrEMBL
MQSSSDSIKLLQITDTHLFEADEGSLLSVRTADSFAAVIQEVLHRQVQFEYVLATGDISQ
DHSAESYQRFAEGIAPLKKDCFWLPGNHDYKPNMGSVLPSPQIQAVEHLMLGEHWQLILL
DSQVVGVPHGRLSDQQLSLLEEKLAENPQRHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFENVKGILCGHVHQDMNVLYNGIRVMATPSTCVQFKPNSDDFALDTESPGWRELE
LHSNGDITTEVNRLPDGQFQPDFTSNGY
>A0A7Z8D318|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteus mirabilis|TrEMBL
MESQLELSVDQQHTVRILQITDTHLFANVDDTLLGINTYRSYHAVLDAIKQQGLSIDLIV
ATGDLVQDQSFAAYQHFADGIARLPSPCVWLPGNHDYQPAMIDALNQAGILSAKQVLIGE
HWQLLLLDSQIQGVPHGELSDCQLDWLTRCLESHKERDTVILLHHHPMPSGCTWLDQHSL
RNSHQLAERVKDHPQIKMML
>A0A4Y7RSU8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pelotomaculum propionicicum|TrEMBL
MSIFLYCTRLITHFYLHSYAGNKMLHESGASVFMVVINNEELCTAGSDHAVITWVTPGAK
TDTNILLGEDPKILSQYSGLPDTEYHQVEVSGLKPSTRYWYTVESGGVSGSLNSFMTLPA
PEGKLLFSLGLISDVHAAFGDSVNDVNEKYFGKLTDYSGALFEQCVRDMKQRNVNLVIIT
GDLTDSASELQYQVLKRSLLPAFGDIPYVVCIGNHDKYLKYAGRGEQGFLQYIANRAATR
SIFSIMGCQLLFLDSCVPDKDWGQIGGEQLSWVEERLREGGGRPAFIFLHHPCNGFDVWL
GAKDYRRFQQTIRRFPEVRGVFYGHMHHHKVSTSRFVTGSLPYVELPATVQFPCSYAVMR
VYEKGFEYNAYKISRLDLSEMSRERTIFKHGGMTIFNLYSFGGIGDRSISYSSGRLHRHK
QYELSITAEHAEAVELLARAQAAGGASCAPGAKSGKTRVILARHDSLGLALSSHLRKIRL
HGVKASIVREGSWGLPEELKKTNSK
>A0A7C6B471|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rhodobacteraceae bacterium|TrEMBL
MQPDTPFEDLPPGALRLLQITDPHIFGNPEKNLLGVDTRASLAQVIDRVSTSVSGLDAVL
LTGDIVHDNSDAGYLVARELLSRLHAPVYVLPGNHDERSRLPLLQSGNSRTDKRIELGDW
RILMLDSTRAGDESGELADKELRILEHALNERPERHALVCLHHHPVPVGSAWLDKIGLRN
SDAFFELLDRHANVRCVLWGHIHQAFDQRRNGVRLLGTPSTCIQFMPGKTDFEVDAQPPG
YRWLALLPDGGIRTRIGRVEHVSGGLELDSEGY
>A0A7V1FSH3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Halopseudomonas xinjiangensis|TrEMBL
MPPTATTINYVSLIQLTDSHLFADPADRLLGMDTFASLNAVVDQIIAERPAMDLVLATGD
ITQDGSEAAYRRFMKALERLSSRYLWIPGNHDDAGLMADLGSESGLTEPWVDIGNWRIVM
LDSSIPGAVPGFLRDEQLRLLDEALDTAQTRHVMICLHHHPVDVNVGWMEPLGLRNAPQF
LQRLEGCKQVRCVLWGHIHQQVDQMREGVRMLAAPSTCIQFAPHTEDFATDEQQPGYRWL
RLFDDGRLETGISRLAAGRFTPDPGATGY
>A0A2H5W309|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR10|TrEMBL
MPWIVRMLLLLGASLLILYGYVIWRLAWALAQRTGRSTQHWQKRLWPIAALLNLYPAVAI
GGYLLDASFWRTALRGGHPLVDALLTYPFWIGLLVALQLFLIFLLLEAGRGLARFWMKSA
DHGIARATLGFTVIVLAYTPIRAYLDTRQIRVREQVIASEKLPSDMGELRVVHISDLQLD
ARTDAALVRRFIERVNALRPDLVFFTGDLVTSGTEYIEPAAAWLGAVRARYGVYACLGDH
DYWADPRRVPESLSRHGIVLLDDASRSISAGNISLRLTGVTNIYRRRPSPETLARLAEEK
PAGRFSILMAHQPSPSLVHWAKDQGYDLFLAGHTHGGQIALPLFGLRLALARLETPYVSG
SYDVGSLWVNVTNGLGLTFAPLRFHAPAEIVLLRLTPLKAESPR
>A0A372BI31|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. JW|TrEMBL
MTFQVSTLSQKDHVIIQITDTHLLEYPHLEFVGMNPEESFHAIIQQILKKHPETDAIIHT
GDLAQAPTPITYKRYIQYMQTLGLPFFQTLGNHDNVDHFPLHKENHQEPVVICLGNWRII
LLNSAVKGQINGHLSPEQLQNLAALLEEFSDHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLTTLGPFKNVKALLCGHVHQDSLNTWQGIEFFSTPSTSVQFKPFSNEFALDQNAPGYRY
IRLKNDGSFETEVFRLENFQGLINTNISGY
>A0A522VH59|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylococcaceae bacterium|TrEMBL
MFDAAPGKPQYYDKKQRVFDGWKQHGKDSGRVFKDVAAKDLGQIKRWTDGCSLIYLTEKI
YLRMVFMVCRTEAASATRVIKVLHITDPHLLADPEQRFMGLDTAETLQQVLALAQQSGDW
PADFVLITGDCVQQATQESYARFRSLLAPLQLPCYCLPGNHDEPALMKTELNRDAVYYQR
QIPAGNWQIILLDSSIPGNAAGHLKDSELALLASKLARESDKFTVVVMHHQPVPVYSEWL
DTMALAPDNRENLLQLLGKNAQVRLLLWGHVHQEFDGYLGSLRLLATPSTCFQFTPKSEE
FSIDRSAPGWRWLYLHPDGTLDTHVARLPQVPASLDVDAGGY
>A0A6L6IIH0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia alba|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYRAVLDAIGARRNDYDLIV
ATGDLAQDQSAAAYKHFAEGIASFRAPCVWLPGNHDFQPAMYSALREAGISPAKQVLLGE
KWQILLLDSQVYGVPHGELSDYQLEWLEQKLAGAPERYTLLLLHHHPLPSGCSWLDQHSL
RNAAGLGDVLVKYPRVKCLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDMIG
PGWRTLELAADGTLETEVCRLTGNGFRPDTASEGY
>A0A7Y0VMV9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. WS 5413|TrEMBL
MPSVSIVNPDAPALLVQLSDSHLFAEADGTLLGMNTRDSLQRVIDLVRAQQPQIDLLLAT
GDLSQDGTLASYQLFRELSQQVGAPARWIPGNHDEPQVMAEATMGSALLEPVVDVGNWRV
IMLDSAVPGSVPGYLADVQLQLLAQALSEAPGRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERHGVRLLASPSTCIQFAPGSEDFNVSEQAPGYR
WLRLHADGRLETGVERVQGFAFTVDYASNGY
>A0A387DSM6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lactiplantibacillus plantarum|TrEMBL
MRPLQVIQISDLHLTPRGQVPAHGQQYDPWGKLANIIDDIRRLPTMPDLIVFTGDLIHDG
SADDYQRLHAIIHTMEAEFDCHVRVILGNHDRRAAFYEGYLPADPGPYYASRMRIGNNDF
YFLDSKVSGYEAGWLAPQQLQWLGKHLRQAPTKRAFLFLHHPLDGPTMTNMHYAILQNTP
ALLSVLRGHNLGGVFSGHVHFVSSYLIGDNILNVVAGSAAYAIDCHDPHHHYVHEGSSYQ
IITIDRGQVGVTTRQLLHGKAVIDELTIPDTKFVGRAPQGYE
>A0A6S7ADQ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter kerstersii|TrEMBL
MPRVHSLARRHDAPAMLVQLTDSHLFGEPDVAMLGVNTDASLRAVLRQIEADGKHPDLLL
ATGDLSQDGEAAAYRRFAAILGEAGSLAGAQIRCLPGNHDQPAVMRQELPQWSTPVTDVG
AWRVVTLDTTVPGSNAGHLPDSQLDMLEAALEAAPGRHTLVAMHHNPMQIDSHWHDSMMI
DNPQVLFKRLTRWPQVRVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNMA
PGYRWIKLYQDGSMATGVRRVQDALWHTALAPDDAQAA
>A0A6S7AFZ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter kerstersii|TrEMBL
MLIAQITDLHMRTPGDKAYGIIDPAAFLAPAVRALNALTPRPDCVLITGDLTDLGRPHEY
AVLREHLQALEIPYFLLPGNHDDRAQLRAAFPDHAYLQDGGDFIQYAIENYPLRMLSLDT
VVPMKSHGELCQDRLDWLAARLAEQPDRPTLVLMHHPPFLTGIEHMDAIGLLAGAPELER
IIARFPNVERVLCGHLHRTIFQRFGGTIASTCPGTAHQLALELGPRPTLQYIMEPPGYQL
HWWQGKNLVTHHAVIGDYPGPYPFA
>D6IDW0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli B185|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A5E4R9M9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea morbifera|TrEMBL
MLLCQITDLHVTRPGALACGRVDTALALRRAIAAINHLQPRPDAVIATGDLIDTPHPSEY
EVLRECLAELTMPLYLVVGNHDHREALRDAFPDHAYLRTGYEFLQYRVDLGPMTVLALDT
QDPPGASGHLCDSRLAWLDAQLHACAGRPTIIAMHHPPFETGIAFMDGYGLSSAGREGFA
RVTSRHGHIERVICGHLHRSIQAQVPGAPNVMASTCVSTAHQITLGLAPGAPETISLEPP
GFALHLWQAGSGVRTHQAFVGPYDGPYRFDGTSVS
>A0A6I2JCZ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. RIT698|TrEMBL
MQSEILPQTDKDRVIIQITDTHLMDKPDAEFVGINPEESFHAVMDDIQQRYKNIDLILHT
GDLAQAAFPETYARYLEYMQRFGVDFYQIPGNHDNINLFPFHSPEPIPAVIELDQWRIIL
LNSAVGGRTDGNIQTEQLVHLKRLLEQLRDKFILIACHHNPFDMHSKWLDQHKLKNADEL
KAVLEPFDNIKAVLHGHVHQESYNVWNGIQFISTPATCVQFKPLSQEFSFDPIAPGYRCL
HLKANGEFETAVHRLDHFKVTINEEISGY
>A0A7C6X715|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MQPLKTIPYTNVVQLTDSHLFAELDGRLLGMDTHDSLQQVITLVQAEQAQIDLLLCTGDI
SQDGSSDSYQRFAKEVGALGVPMRWFAGNHDERLALQQVSAQTDWLESVYDVAAWRIILL
DSSVINKVHGELGQDQLNILEHALRSAGERHVLIGLHHHPVPINSAWMDKIGLHNAADLL
SIINQYKNVKAVLWGHVHQEVDQYLHGVRWLASPSTCVQFTPQSEDFSVDTKAPGYRWLR
LYDDGQIQTAVSRVENIDFEIDYSIKGY
>A0A7U9B9X2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli TA271|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7C1MNJ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MMRMSVPEGIKFLQISDSHLFENAGKRLIGVNTEASLRAVVGLASKEEDVTGILATGDLS
QDGSVESYQQFADIVKPLGVPVYWIPGNHDNSYYFHHPENFPLSSRSVINAGNWRILLLD
SVIPGKESGHLSTSELDYIEKHAHDGERHILLVLHHQPIPCGSSWLDTMILNNADDFLQL
IANKASIRAVLNGHIHQDRRQEIAGVSFISTPSTCFQFKPDTDRFSLDARMPGYRRLILK
YDGGIETEVVRLEDYDLHIEPAVVGY
>A0A7S6N3D1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MAHPALRILHITDTHLFAEADGRLRGVDTCSSLQAVLEAATSGPWPADAILASGDLSQDE
SAGAYQRFRGMLAPLGVPVWCLPGNHDAPARLADALAGPPFQVGGAVVAGSWAILLLDSC
IPGEHGGRLSRAQLAWLADALEEHRQRHVLIALHHHVLPLQSRWLDELGLANAAELLAII
DRAPQLRAVVAGHVHQASDIDRAGVHFLTTPSTCFQFLPEAATFAVDRRPPGYRWLELHA
DGRLDTTVAWIEPPQ
>A0A3M2CAR3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
FWGGSPSSDQGGTGVTLIKFVQISDSHLFPEPRSCLSGVDTRQSFLNVIRHIQTNHSDCQ
FLLHTGDLAQVPVVSVYRWFLGQMGVSGMPCYCLPGNHDDPAMMRHALDHSPVHFQGCMD
VGGWRLIMLSSMQYGSPNGRLNQVEMDRLRHHLEQANDRHVLVILHHHPIPSRSEWMDAM
MLENSEDFMCCIGRHPQVKGVLFGHVHQAMDCHHLGVRFLSAPATCFQFKPRTRSFQLDS
LTAGYRWFCLHADGRIETDVEYL
>A0A7W2E600|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium aroidearum|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKARQDAFDLIV
ATGDLAQDHTLEAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALAEAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHSLSAVLDRYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLFPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A379AUU2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Avibacterium gallinarum|TrEMBL
MVNTYTYPTDNDVVRLVQITDPHLFKDENGELLGINTQASFNQVLSEIKQSDFDYELVLA
TGDLVQDSSSEGYLRFCETVQCLEKMVFWIPGNHDFQPKMFDILNHNNGNINPLKHLLIG
EHWQILMLDSQVFGVPHGQLGQYQIDWLSSKLKDYPERYSLVVLHHHILSTNSAWLDQHN
LRNALDLAYALSPFNNVKGILYGHIHQAVDSEWKGYKVMATPSTCIQFKPDSNSFALDTL
QPGWREIELYNDGRIETRVKRIQQATFLPNMLGEGY
>A0A1X3I2N2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli M056|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A2J8NHF9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pan troglodytes|TrEMBL
METLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTF
LDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLA
KELEDLNKWGLNIFNVAGYSHNRPLTCIMYAI
>A0A8C4W275|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gopherus evgoodei|TrEMBL
FFQNSHFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSM
SRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLPDRASNKRSPMCNQPSINKA
AITGKRD
>A0A7J0AXL8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alistipes sp|TrEMBL
MFRLIIILSSVAVALDLAAWQRIYRRWRRGGWLLALCLLDDMLPLAAVAAQALLPDNTRG
VVLALMWIMLLYAITVIPRAIYLLFALWSCRRIWRVAGSAVAAAAVLAAIYGTFVTRTDY
RVVGVAVESPDLPPAFDGYGIAIISDLHVGSMLHPAAECRRIVETVNSLDADLVAFCGDL
VNVRYDELTGELIGILGSIRARDGVVSVTGNHDTGIYISDRASLPAAENLSRVVAAEREM
GWLPLEDTTVWIVRGADSIAVSGISFREQWHDARHSRHIPDVDPTGIYENVDRQAFDITL
SHVPQLWETLLATYKVDLTLSGHVHAMQCKLPSGGRGLSPAQAIYPRWSGLYREGFSSLY
INDGIGCVGVPTRIGACPEITFLRLEYSSK
>A0A564G0S8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium dankookense|TrEMBL
MAAARTRRPRGDDPFVFLHVGDLHLTGRGEANARDLAAILDQIAACAPREAFDFVYLPGD
IAEDGTARQYAILRAALARHPALPIRLIPGDHDRQHGSVAAFHDLFTEVADSAGGWRQPP
VVNRLPQPEAERDVAQYYYAETVSGVRCLFVDMVSAGFGRKGIGLDFRLGRAQTCWLSDE
ITAAAGHGQPCAVFMHAYPDDLRVPDERLDIAGLIWGGRVRLVEMGHTHYNELAHDGRTL
YAAARSVGQNEDGSVGYAVAAIDGPVTSWRFRALDRQPPFVLITSPADRRIAAVPASAET
SGMVPDARGRIRVRALVLSDRDPAYCHCRVDCGAWTVMERVSARSFEARIAWPAGARSLQ
VEAVDARWPGHGPDFVDTDVIEPPDLAAEPQAEPAIPDRPGSDAVRIGAWLQKGVRGDQL
GPNRAGRKW
>A0A7Y3Z9C6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio rotiferianus|TrEMBL
MQSSSDSIKLLQITDTHLFEADEGSLLSVRTADSFAAVIQEVLHRQVQFEYVLATGDISQ
DHSAESYQRFAEGIAPLKKDCFWLPGNHDYKPNMGSVLPSPQIQAVEHLMLGEHWQLILL
DSQVVGVPHGRLSDQQLSLLEEKLAENPQRHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFENVKGILCGHVHQDMNVLYNGIRVMATPSTCVQFKPNSDDFALDTESPGWRELE
LHSNGDITTEVNRLPDGQFQPDFTSNGY
>A0A084A2T7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia sp. DD3|TrEMBL
MESLFRLPVAGGAKVRILQITDTHLFASQSETLLGINTYSSYHAVLDAVIAQQCEYDLVV
ATGDLAQDHSLEAYQHFAAGMKRLPVPCVWLPGNHDFQPAMVCALAEAAISPSKQVLVGE
HWQILLLDSQVFGVPHGELSEYQLGWMERCLQAYPERYTLLLLHHHPLPSGCTWLDQHGL
RNPHVLAAILLRYPKVNTLLCGHIHQELDLDWYGRRLLASPSTCVQFKPHCTNFTIDAVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A2H5ZIM4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR30|TrEMBL
MAKYVLPMERKKQEYLAERERFFAELPKLSRRDFFKTAAKAAAVATAFWKGFPPHSFQLI
RVAEAKESQPKFTFAYISDTHILDKGLNHRFVKACQKAVDDVNALDPQPDFVLFGGDLAQ
LGKPEELSLGKQLLDQLKAPVRMMVGEHDWYLDLGEKWREMFGEPTYSFDHKGVHFIVLN
SVIVEDYWTEPKMTPMERMLAMAQLDNPNGRPFMVGEEQREWLKKDLAKVDKKTPIVIFS
HSPLYKYYRPWNFWTEDAEEVHKILAPFETVTVIHAHTHQVLTHRLRNITFHGVLSTAWP
WPYAPQGIPELTVQMVRADPFNQFDGCGWGSVNMRPDGQADKHYVLWDRNPMTVTFDHVR
RGKQGMAELAKPLQGRVDWPSY
>A0A386K4P7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter phage phiT5282H|TrEMBL
MNRRDFLILSAGVALSGCDFFGGANKANSDKKLRFAIASDGHYGEKITDYKKNYSVFVSA
VNEFSKNNNVDFCVINGDIVHDDKKYFQPAKKQLDLLSMKYFVSKGNHDPATPEEWVNIW
GYPMDFDFTIDRNAFLIMSTSDLAGTYLCPDLSWLTNKLREHKAKENVFIFMHINPVAQT
HFAVECDQLLSLLSEYKNVKAVFNGHDHDHDEVLIKNDIPFVFDGHFGGSWGTDYHGFRI
VEVDQDNTITTYMMDPSKKIKSSSL
>A0A707YV67|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella typhimurium|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDVDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETKVHRLQDTRFRPDTASEGY
>A0A829ZKK6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lactobacillaceae bacterium|TrEMBL
MKIAVSSDLHLDLNHADVAEIITQQAHYLTHQEIDHYFFVGDAFNDFEQTSVYFAELQSQ
LPTTKVHYLAGNHDMLKGVTYEQLENLDDDLYFHNRFIDIPQTNWRIIGNNGWYDYSFST
YESNVKEVAKWKRAYWVDRPIMQPMNDPERMAIVLDQVEEALQQARNQQKQVIFMTHFAP
IREALPHPIIKSARRQRMWEMTTAMLGSRHLGALLARFSEVKAVFYGHLHYAQPLITVGN
IEYRNQAVGVRRKNSGEWEGKSLLDQWIDRLYTKKI
>A0A1J1HIG6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clunio marinus|TrEMBL
MGCSPSILSSLSNNNNRKDSGLYCSNNSETNSANNKNDINIDSNTSTALANQILVQSSVT
GKDAMNKDYIKKDSIVSVGHMAHGFTIIPSTIRRATIGTSAPSGRIGHRKSSLALTPEEE
PTFETTIVDKIHKTTFVTNMVDSCFKVFKSNCFRKSSISSQRSSVFQIDKRPISENISKD
KKFNTTANATPIDTDKTLSYDCDVEYSTFELDPNVILRRHNRFYLRSVSATTSCDAMSSE
EDDNENLDILYPLPRVNTHERALSEESNQQITDKINSDKNNSKSSTSKDGLKHNDGGRVR
DNSNFLKTFFKRKYRRKKCNDGKIPNLIPPNPAVRVLLVFYKDDHIFDAMARSCERLGFE
SFRAKTSETALEMFQHPVNGGYHLVIVDSRCKNIDVESFGRSLRNSKGSQYTIIIAIVRK
SVFEKDDTAVLSMLEVGYNRCIIESPHVSVCCSELRQIQHSLIRPQNVIASQQALYSALH
HVKDTIIITDYALRIQYANKTIERILGYKIDEIVGRPLQDLINSDVSLLLSQTNRLKEYD
GVITFNRKAQDQIIIHVRATPIACLGKATTHIIIALNHTQIGGYEMGLPSIPQAKEPRGS
LHSIRRGSFDIRSITSDGLRRTSLAKLSSLPLEAPITKVLSILAQVQENCSNDEAKLLDR
VIEFLKREGLYSPQIKEIRPEDPVATDLIGALLTQGPSNNVSSRRSSNESIIRSGSRQSS
SGNTAIKFKTPPQVSELLSTALDWDFEIFRLEELTDKNPLVFLGMELLRRFDVFNTFNCD
EITFRSWLIVVESHYHSINTYHNSTHAADVMQATACYLQQLANRDLKIMDRLDEATALIA
SAAHDIDHPGRSSAYLCNSDNSLAILYNDVCVLESHHAATTFRLTLSDDKINIFKNLDRD
MYKLARSVIIDMILATEMTRHFEHLAKFVSVFGNDVENKDVPNDEDNQMLIRRMLIKCSD
VNNPTRPLKFCVEWARRIAEEYFTQTDEEKRKGMPIVMPMFDRASCSISKSQIGFIEFII
QDMMNAWDGFIDMPELIQYMQYNYDSWKTFEVQGINTLSDIKRKQMSISNQNDTQHFPNV
KLDEVM
>A0A5A5R4V7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcystis aeruginosa NIES-2519|TrEMBL
MRPFWLESLQVERLTIAIASLPAALQGIKLVQWSDLHCDEQHLPEAVLQEAIAITNQEKP
DLIFLTGDFITDSPRPIFTLVESIKALESQGGIYACLGNHDSYPPHARETVRAALTSVGI
RVLWNEIVTPYGENFPIVGLADYWSGEFFPQILEQIAPDIPRLVLSHNPDTAMVLRDWRV
DLQLSGHTHGGQVTIPGMGSLPIVLEKLRRSLPDPYRQWVPFHRQFSRVVRYWQWSEGFH
RVGENQLYVNRGLGTYFPGRLFCPPEVTVITLINSSQ
>A0A3A6RG09|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. LS-2|TrEMBL
MPSASLNSSSVLLVQLSDSHLFAEADGKLLGMTTRDSLNAVVDLVLAEQSDIDLILATGD
LSQDGSVESYQAFRESSERLNAPKRWLPGNHDELHEMAIAAQQSDFLEPVVDVGNWRITM
LDSAVPGSVPGYLEDKQLQLLAQALSEAPQRHHLICLHHHPVAIGAAWMEPIGLRNPEAL
FSVLERFPQARALLWGHVHQEFDQSRQGLRLMASPSTCIQFAPDSEDFALDSLAPGYRWL
RLYDDGQLETGVSRVAAHLFEVDLSGAGY
>A0A6H9HUE3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteobacteria bacterium|TrEMBL
MADPALSILHITDTHLFAAADERLRGVNTCRSLRAVLKSASTAARPVDAVLATGDLSQDE
SAGAYRRFRELLAPLAVPVWCLPGNHDAPERLAATLAGPPFQVGGAVVRGGWTLLLLDSV
MAGDHGGRLSAAQLDWLAAALEEHRQRHVLIALHHHVLPLQSRWLDELGLYNAAELLQVI
DRAPQLRAVVAGHVHQASDILRNGVRFLTTPSTCFQFLPQVASFAVDRRPPGYRWLELHA
DGRLETEVAWIEPPQ
>F9GT83|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus haemolyticus M21127|TrEMBL
MKNAFVYQTEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNEFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQSPMDGAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTKVKRIQQAKFLPNMQEEGY
>A0A6J2XNP0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sitophilus oryzae|TrEMBL
MSVCKHCGSTIENSVLVSPSPIQEEDNENDNTDRCSGGWLCFKQCFSGGSNERRKNDKGD
DMSARYLRENRYQRRTIQFDFDLNSSVSSRRLHSTISSSILKSGKRGPNELKYGLIIPNI
KHQLKLLLVFAQLDPVSETFTKAAEKLGFEVTLCHTDISALEEYQTKSHDLVIVDNRITK
AFDNDLLCRSIRNTRGSQHTVMIAVVKKSAFERDDITITSLLESGFNRCLIETTNLLTCV
NEMILLKHSDIRIMAQHATCQALYTALDKCKDLVIVTDDTYKFQYMNTACERQLGLRQED
TLGKTLQEQLVYDTVQINTMGSSLLRAREWSGPMTLKRKSTQDPIVTSCKAVPFSCAGRM
PTHFILVFDTNSIDPNMLSQSRGSIHSIRRGSTDVRSVGSDYLRRTSLAKLNALPLEAPI
TKVIGLIDQIRESLGSNPQAIQLIDRVEDILKSSELYVSHVKEDSKVKADEPVVSDLITA
LLSKTPQPTLSASSRRSSNDSSVFRPSRTGLIKAPAAIRDLLETSLTWEFDIFKLEDLSR
RRPLQHLGMNLFNHFDVCGSLNCDEKTLSNWLTVIEANYHIENSYHNSSHAADVMQATAG
FLEKERMKSIMEPLDEATSLIAAAAHDLDHPGKSSAFLSNSNNPLAILYNDVTVLESHHS
ALMFKLTLGDERVNIFKNLDRDTYKLARHNVIDMILATEMTKHFEHLAKFVNVFCPRSSI
GSDMDQPDDYNALLSPENTTLVKRMMIKCADVSNPTRPLRICVEWARRIAEEYFQQTDDE
KMRGLPVVMPMFDRATCSIPKSQIGFVDYIINDMFEAWNAFIDMPELLTYMRQNYIRWKE
FDEQGHTTLSDIQKLQATVLSPSVSSAIKSD
>A0A5X6EJ98|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Aqua|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A857JMT8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraglaciecola mesophila|TrEMBL
MSYKIAQISDCHLFADKHQVGYQDINPYNSLQAVLANVASNQPDLVILSGDISAEDSADE
GLASYQLFSQLWQQSQLAAPLLVIPGNHDHLEPLNTELNDSVGWPVSLNAGPCWKVHGFN
TKTDDSSGEISASELAYLTEQVHLNPRLHHLLVVHHHPHACGGWMDNHPWRNSDVFLQRV
AQLPQIKVVLHGHIHHARVMHSEQCIFMSAPSTCWQWANTKEFAASHEAPGYRMLELNDN
GRVETRIMRI
>A0A411WND9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Jinshanibacter zhutongyuii|TrEMBL
MESLFQLPLARGSKVRVLQITDTHLFAGADETLLGVNTLKSYQAVLRAVAERGHDYDLIV
ATGDLAQDRSFAAYERFTAGIATLPAPCVWLPGNHDFQPAMVDAMAAAQILPSKQVLLGE
DWYVILLDSQVLGVPHGELSEYQLNWLDRSLTQYSDRHALILLHHHPHSSGCTWLDQHSL
RNAHMLAEVLDRHPQAKTLLCGHIHQDLDLDWNGRRVLASPSTCVQFKPHYTNFTIDDLA
PGWRYLDLYSDGSIETTVCRLEGDVFRPDMNSDGY
>A0A7U4QA58|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea vagans|TrEMBL
MDSLLTLPAANGSEIRILQITDTHLFAGKHESLLGVNTWSSYDAVLDAIIAQQRDYDLII
ATGDLAQDHSVEAYQHFAEGISRLPRPCVWLPGNHDFQPAMVDTLAAAHINAHKQVLVGE
QWQIVLLDSQVYGVPHGMLSDYQLEWLDNALSRFPQRHTLVLLHHHPLASGCTWLDQHSL
RNSHQLDAVLQRYPLARTLVCGHIHQELDLEWHGRRVLATPSTCVQFKPHCTSFTIDTVA
PGWRWFTLHPDGGLETEVNRLDTDAFCPDLDSEGY
>A0A023FCA3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Amblyomma cajennense|TrEMBL
TRSASDLSAATNNSTANSTGRCRPPGESQHRNSRPQCLEGPLRRAANLGEIVTDRTVPLL
AKLDGSTPDDGRKGTVALKFGSMYLTVPSIKVMFVFGKEDAQYNALKWAADKMHYECALS
STSEAAIDNYLNGQPHLVFVDARSKSAIDPVTLCRTLRGFRGSQFTCIVAVVKXXXXXKE
EAAVIPLLKCGYNRWFTETCSLGVCLNEMIQIEHNDLISLWKLRASEALFSALHYTRDGV
IVTGASHEIQFMNRAAEKLVGYSVEEMLGVDAQELHRTDSLKTDVASNINMQLKKGKEWE
GTLFHKRKSGECIPMWSKIAPVEIHTGKSDHVVYIKECPFFMEKPFSPDAVGMNRRQSFA
KFHAMTLEAPITKVINMLVSTQENSSAMVAQALDRVIDILRSTELYNPQLGVGQGKSEDQ
MTSDLVTGLINTGQKPTGVRRLSHETSLMKVNVVNATAPSGVLPSLNTAPPKIKELLEND
VKWEFDIIELETLTGRRPLIWLGLSLFSKLNVHTSLECDDATIRNWLQLVESHYLDNPYH
NSTHAGDVMQATAYFLLKLRKKDIFDPLDEAICLISAVVHDIDHPGKSSPFLCNSDHELA
ILYNDRSVLESHHAAFAFKLTLSDEKVNIFQKLERDVYRSVRLSIIDMVLATEMTKHFEH
LS
>A0A2S6X463|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces sp. MH60|TrEMBL
MLVLAHISDLHLDGSPRATERAERVRDRLWRLPGRVDALLVTGDIADHGTEAEYEEAARV
LGLRDGSAPFPVLTCPGNHDSRAPYRKALLGRPAADGPVNALHVFNGGAVLMCDSSIPGS
DEGELDEETYDWIEASLDGLDGDRPALLALHHPPTALHHPLPDSYRLRHPERLAALLERR
PRIAGLITGHAHTPAATVFAGRPLVVGPGVTWTLRLPWEGAEIADRDAPVGLAFHVLDDA
GRLTSHFRTVA
>A0A5F8HI17|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Monodelphis domestica|TrEMBL
NFHGVRNGPSPSPGRSPLDSQASPGLVLPPSAPHSQRRESFLYRSDSDYDMSPKTMSRNS
SIASDLERDFHILTYFFNYSSYALPQVLASLRSVRSNFSLLANVPAIVGNKKSPMGNQPA
VCKATLSGNST
>R4GIL4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gallus gallus|TrEMBL
MTAKDSSRELATPESEIYIRTFKEQMHLELELPKLPGNRPTSPKISPRSSPRNSPCFFRK
LLVNKSIRQRRRFTVAHTCFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFL
YRSDSDYDLSPKTMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTANK
RSPATSQPPVSRVNLQGMCGSSVITCQQRGRLIAHGFTPGCSSAPPARCSAELLLGYSCK
TNAGAPPGSGCCCLNGLGFVFTLVLA
>A0A2G1ANP2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSHNFDYQAILA
TGDISQDHSAESYQKFESGIQPLAKPCYWLPGNHDFKPNMGSVLPSPQIQCVDHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLSEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHSNVKAVLCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTEVRRLPHGQFLPDFAAGGY
>A0A7M2JY08|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio coralliilyticus|TrEMBL
MVSAGRRSIFRFLVLKVTSCSSDGSIRLLQITDTHLFEATDGSLLSVNTADSFNAVVDAI
VEENPVYDAVLATGDISQDHSEVSYQRFEQGIVPLKKKCFWLPGNHDFKPSMNSVIPSQQ
IQQIDHVLLGDTWQMIMLDSQVVGVPHGRLSDKQLNLLEEKLSQYPERYTLILLHHHPLL
VGSAWLDQHSLKDSDDFWQVVDQHNNVKAVLCGHVHQDMNVMRNDVRVMATPSTCVQFKP
NSDDFALDYQSPGWRELLLRDNGEIETQVKRLPAGCFQPDFNSAGY
>A0A2A3ES87|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Apis cerana cerana|TrEMBL
MGCKSSVLECVEDTGEEKRKESDMMEQGFLFEKTEYDILRRKSSFEDIDDEKNADYSTLI
GSHDTEPHPLTNSVPSLIKILLVFPKDDQQMDILATTSRRLGWSVSVAKDAEKALEFFQA
RGHELVIIDHRGQRAAEADIICRAIRASPFYYNSIIIALVKKSYLMHSESEKIVTLDLLE
IGYTKTLMECAHERILINELVGIYTSGILPRTQLVAANMLYMALDRCRDMIHVTDDKYII
QFANKISEKILGYRVIELWGKNITDLILYDNFIQMEQHIIKGREYDGNLNCIRRNNQMVT
VNCRVIPFAYFKKPTHYIFIYDTTYLSENIQPLLQPTTHPKTVVISQKRISEVNFKGIQD
VRRRLSKRDLQTLQLEAPITKVIGLLTASIKEDTASETKLQIEKAIDILKTTELYSPVFK
EQGDPAADFIEALITPKKSWDVKKPSVESIRDTPSKTLAASTRMQIKGYRGPQEIAEILE
KSLEWDFDIFKLEVLTEKRALLFLGMTIMNLFRVPARLGCEEKIVQNWLIVIEANYDSMN
RYHNSTHAADVLQATAMFMQTERLKQVLEPLDEVAALIAAAAHDIDHPGRSSQFLCNSDN
KLAILYNDLTVLESHHAALTFKLTLSDDNVNIFKNLERDTYKQVRQSVIDMILATEMTKH
FEHLAKFMNAFSTRIPEMYIEGSQDLDISAAMLPENIILVKRMIIKCADVSNPTRPLKYC
VEWARRIAEEYFSQTDEEKQLHLPVMMPMFDRITCSIPRAQIGFIDFIINDMVEAWDVFI
NMPEIVGFMRQNYDKWKEYNSIGLDKMVPIIYSRPLTTSLL
>A0A3N4EGB6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella psychromarinicola|TrEMBL
MLKDAVHYSVTENEPVRLVQVTDPHLFSDPEGQLLGVNTAQSLQAVLNTYIATQYPAHLL
LATGDISQDYSPESYQHFVQKIEMLNLPCHYLPGNHDDPRLMSLRMQGEKVFGQQRVVIG
KWLILMLDSTLRGKPGGHMGERQFALIDAAINAEPDKHVLLVMHHNPILMQCAWLDQHCM
MNGEEFLQRTSRYPQVKGILWGHVHQQVDNIHLGAHGPIQLMATPSTCIQFKPLSSYFAL
DHLQPGYRLLELAGDGSIRTNVYRVPGNLFAPDNEASGY
>A0A3L7DPU6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. SBT000027|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIKPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPKRNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAILCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTQVRRLPNGQFSPDFDAGGY
>A0A221USK4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arenibacter algicola|TrEMBL
MKRRLFFKNAATASIGLGLTKYSSKDKPVQPFEKGLPFCVTVSENKLQFFSEAIKESIKI
VHIADTHLFMDDERGVPYAMYSGRMAKAYNQTKHFKTGEATNPELAFAAALDFAKESKAD
LITLIGDIFSFPSEAAVEWVAAKLKEVDIPYIYVAGNHDWHYEGMEGTLEDLRDKWIKER
LLPLYQGKHPLMAAYDLKGIRFLAIDNSTYQINKEQLDFFKEQVSSEVPLVLLVHIPMYA
PGKSISFGCGNPDWGASSDQNFELERRLKWPEAGHSEITFDFHRAVFSAPNLLGVFAGHI
HRFSVESIKGKPQIVTDDNASGGFLDVDFLPLEPKDQSLIF
>A0A7Y4EYW7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio alginolyticus|TrEMBL
MQSSSDSIKLLQITDTHLFAADEGSLLSVKTVDSFNAVVADVLRRNVAFDYILATGDISQ
DHSAESYQRFANGIEPLEKDCFWLPGNHDYKPNMGSVLPSPQIKAAEHVLLGEHWQLILL
DSQVVGVPHGRLSDQQLTLLEEKLAEHLERHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVERFDNVKGILCGHVHQDMNVLHKGIRVMATPSTCVQFKPNSDDFALDTTSPGWRELQ
LHACGDITTQVGRLPDGQFQPDFSSNGY
>A0A7M7T8B0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nasonia vitripennis|TrEMBL
MSDTRRLTNPTLRISGRIEGSDTFGEDVAASSTQTGQAPFGWLNGLFGFLRCSRRRKEWH
ASERTTSSQLAVSSAFILRKNPQEINFNWLAPNAVSDVFKILLVFPRADQQSEILAGVAQ
KLGWTVSEARNAEEAVVLFRTCCHDLAIVDRRGGAVRCQEADQVCRTLIEMKSAKRCSIV
ALVKKSFFTAPHKEELVILHLLNIGYNRALMECSHEGILMNELIGIYASESQPKSQLAGA
QLLYLAVDKCRDIIHVTNDQHVIQFANKASEKLLGYRQDELLGKSLEEFVTNGHFALMDQ
QLQKGREFEGNFHWKRKLKGLINVNCRIVPMNVPGSKTAFYLYLYDTSTSLESFPSSGSF
QHLQPRPSIQSTFDRRSFELHHPGKPRRSIVAKLHNLPLEAPITKIITLLTQAAEDAMDP
DVKFQIVSAIEILKGTELYSPYFRDDILSESDPIKSDFLGALISVSPVNDTRKSSSMSFG
RHSAIMKILNANQHQQMNAKLLKSPRGPQELEDLLETGFEWNFDIFKLETLTNSRPLYYL
GMTLMNHYNVAERLECDERTLQNWLTIIEANYNSHVSYHNSTHATDVLQACARFMRSDRI
QQILDPLDEVAALLAAAAHDIGHPGKSSQFLCNTSNKLAILYNDLTVLESHHSALTFKVT
LSDDNVNIFKNLHADVYKSMRQNIIDMILATEMTKHFEHLARFVNLCSNRIGDSENGAFE
EDIVDTSAFLLPENVTLTKRMMIKCADVSNPTRPFRLYVEWTRRIAEEYFDQTDEEKKKK
LPVVMPMFDRACCCIPKSQIGFVEYIINDMMEAWDAFIDMPEMVGYMSENYMKWKELNEQ
GINTLEDVIKLQETPELKLYRKEVSS
>A0A0H2VB82|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A6P3UI94|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bombus terrestris|TrEMBL
MRSSERQHEESKTLKGSPRTRRRAKVIRDLPTDPYFSESVLVKGPQNIEAHPLTNSVPSL
IKILLVFPKDDQQMDVLATTSRRLGWSVSVAKDAEKAVEFFQNRGHELVIIDHRGQRAAE
ADTICRAIRSSPAYHNSIIIALVKKSFLMHGEKDKIVTLDLLETGFSRALMECSHERLLI
NELVGIYASALLPRTQLAAANALYVALDRCRDMVHVTNDKHIVQFVNKISEKLLGYKTSE
ILGRSIADIVVYDNFVLMEQHISKGREFEGNMNCKRKNNQMITISCRVIPFSISLKKPTH
YIYIYDTTYLSENIGSLSPTPSQSVYSRGNMIVSQRRTSDMKSSEGRRRSSAHKLHSLQL
DAPITKVISLLSNAITESTTPDTTAQIEKAIDILKTTELYVPSLREDTDPVTTDLVGALL
ASPRKAWESRRSSVESTRVSTTKGFTTTTASRMQIKGFRGPQEIAEILERCLEWNFDIFK
LEILTEKRPLLFLGTTIMNLYRVPARLGCEEKVVQNWLTVIEMNYQSRNSYHNSTHAADV
LQATARFMQSERLQQILEPLDEVATLVAAAAHDVDHPGRSSQFLCNSDNKLAILYNDLSV
LESHHAALTFKLSLSDDNVNIFKNLERDTYKQLRQTVIDMILATEMTKHFEHLAKFMNVC
SARMMDSPQLDDYSDTVDMSVVLQPENVVLVKRMMIKCADVSNPTRPLKCCVEWARRIAE
EYFNQTDEEKRMQLPVLMPMFDRATCSIPKAQIGFVDFIINDMVEAWDAFIDMPEMVGYM
RQNYEKWKEYNDRGISTLPDIEKIQELPELRIYQLPS
>A0A829FVY0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli KTE36|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A6I8VRZ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila pseudoobscura pseudoobscura|TrEMBL
MSQCSTGTGTSGTSSSGGGGNNRPGHRKSSLALALTPEDDPMDVYQRNLMDLKYPTVLPP
NPQLKALLVFHKSDSICEAVASACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIID
ARSSKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNL
AMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLNM
RLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMHVRVVPVACIGSA
PTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTS
LPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLI
GALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKANPIIMELLEESLSWDFDIFKL
EEITDYHPLLYLGMEMFRRFDVFATLNIEENVCKAWLAVIEAHYHKSNTYHNSTHAADVM
QATGAFITQLTNKDMMVMDRMEEAMALIAAAAHDIDHPGRSSAFLCNSNSALAILYNDLT
VLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSV
FGGEEPREHNPQSDEETAILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEK
QRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKY
DEQGVNTLADVMAMQPPMVKLANSK
>Q7MNX9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio vulnificus (strain YJ016)|TrEMBL
MQHTSSDTLSENSIKLLQITDTHLFASDEGSLLSVKTLQSFQAVVEQVMARHVEFDYLLA
TGDISQDHSAASYQRFADGIAPLEKACFWLPGNHDYKPNMSSVLPSPQITTPEQVELNAH
WQLILLDSQVVGVPHGRLSDQQLSMLEHHLQASPEKNTLILLHHHPLLVGSAWLDQHTLK
DAEAFWQIVERFPMVKGIVCGHVHQDMNVMHKGIRVMATPSTCVQFKPQSDDFALDTVSP
GWRELTLHANGEITTQVQRLASGSFLPDFTSSGY
>A0A0H3BTY0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella newport (strain SL254)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2J8GS51|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio diazotrophicus|TrEMBL
MNVSPSIDNPDSIKLVQITDTHLFAPDDGCLLSVNTADSFRAVVKEICTQKVQYDAVLAT
GDISQDHSAESYQRFSESIKMLEKDCFWLPGNHDYKPNMGAVLPSPQIRTEEHVLLGEHW
QMVLLDSQVVGVPHGRLSDHQLALLDEKLTQYPDRYTLVLLHHHPLLVGSAWLDQHTLKD
SESFWDVVKRHSNVKAVLCGHVHQNMDKEHMGVRVMATPSTCIQFKPNSNDFALDKTSPG
WRELELCADGTVKSAVKRLANGVFQPDFDASGY
>A0A3M2FM25|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyanobacteria bacterium J003|TrEMBL
MNEPVYLIQLSDLHLFATDEGRLLGLPTAQSLAAVLEATRHHRPNALLLTGDLAQEPVTT
TYERLATAFRDFSCPVYWIPGNHDEPRAMVPALERPPLRGDRQINLGTWQGLLLSSQADG
KVHGELSPETLSWLDATLSHTGDRPTFIALHHPPFETGAPWLDSSRLQNPEHLFAVLDSH
PQVKLVLFGHIHQEFITERQGVTYLGCPSTCIQFLPRAPEFSLEPVGPGFRHLSLYPDGT
FKTYIERVEIPLTLDFSAKGY
>A0A835NND9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lamprotornis superbus|TrEMBL
MLLSTWVAECWIKAEEEEPEEHWRGCTLNLRKGIKGLFSWINHVIHRAAFQVLEQGTREV
GSRTWSSHSIPSWALAVPSFSPRQPQCVQLVPVMQVTQGELAGVPHALQALLWQSLSRCL
CLVHSFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTM
SRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNNCGPAVAAQGPWEQL
GPVVSLCLCVPSCPRVPVSDPRCPCVPLCLCVSLSLCPYVSVSVPLCPCVLSRGVPVSLC
LSLCPRVCVPVSVPLYAYVCVPVSAPWCPRVPVCVPLCACVRVSVPVCPAVSLCLCPCVC
PAVSPCLSRCVLVSRCACPAVSPCLSRCVLVSRCACPAVSPCLSRCVLVSRCACPAVSPC
LSRCVRVSRCVRVSRCVPVSRCVCPAVSVCPVVSPGSSGSGPAMDRRPQRQPEYMSVCLF
AEEPYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKERCGKKKNQNNPKNQKGGSGG
GRAMRDGSRALS
>A0A4D7J9J4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia heimbachae|TrEMBL
MDSQLEVTAKNSNVVRILQVTDTHLFADTEKTLLGINTYRSYQAVLDAIIEQNLPIDLIV
ATGDLVQDQSPKAYQHFAEGIERIPAPCVWLPGNHDYPPAMVESLRVAGISCAKQILIGD
EWQVLMLDSQLQDVPHGELSEQQLEWMKHCLDNQPERATLVMLHHHPLPSGCTWLDQHSL
RNSHILADYLKPYTNVKAMLCGHIHQEMDELWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELSVNSQGEKQVNTIVHRLNTREFSPDLDSDGY
>A0A6J2DX54|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Zalophus californianus|TrEMBL
MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRNVQLPPLAFRQLEQAD
LKSESENIPRPTSLPLKILPLIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQAN
FVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFA
ALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKGRKKSRPHKL
>A8FRB5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sediminis (strain HAW-EB3)|TrEMBL
MLKEAISYSIDDNASVRVVQITDPHLFADPDAQLLGVNTAQSLDAVLNTINAVHYPADFM
LATGDISQDYSGESYHNFVRAIAPLELPCHYLPGNHDDPRIMRLNMQGPKIFGQRRILAG
NWQIIMLDSTVRGKPGGHMSDSEIDIIKSAVADQPDRYTLLVMHHNPILVNCAWLDQHCM
DNGNDFIKQVAELPQVKGLLWGHVHQKLDQKHPGKHGMVHLMATPSTCIQFKPKSSYFAL
DALQPGYRLLELKANGTILTNIYRVPGDNFSPDRDASGY
>A0A2H5XIR7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR18|TrEMBL
MGRFVLFSVALALLTLTIDGYVYLNWRRFAQVRPALRWTLTVYRILLVLMPLALPVYFLL
FRWWEVEPKLARALFFGFWAVYYVPKVPIALALAVKDGIRVFRYVFQRLRPQAASTALST
QPSHSMSRAAFLQKLGWAAAALPFVAVAHGVLRTLYDFVLYRVTLPIPNLPPALDGLTIG
QLSDLHAGSLFSPQPVLEAITLLLAQKPDLIVLTGDYVNHDADELPIIIPALQQLRAELG
VWGCLGNHEHYAHTPDVVGRLHAQTPLRLLINAHHTFYIDGARLHLIGTDNTGFRQRFAD
LPKALHGLDTDPNGDEFRLLLAHDPTFWDLEVRPRYPDIDLMLCGHTHGGQIGIELGPLR
WGLASLVYPRWAGLYTEPAVAPRGRQHLYVNRGLGTVGPPLRLGIRPEITLITLRRA
>A0A4R3NH35|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia alcalifaciens|TrEMBL
MDSQLKVTANNPKVIRILQVTDTHLFADTENTLLGINTYRSYQAVLDAIAEQNLPVDLIV
ATGDLVQDQSPKAYQHFAAGIERIPAPCVWLPGNHDYPPAMVGTLKIAGISSAKQVFIGD
DWQILMLDSQLQDVAHGELSEQQLEWMKQCLDEQPTRTTLIMLHHHPLPSGCTWLDQHSL
RNSHILADYLKSYPNVKAMLCGHIHQEMDENWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELTVNEQGEKVIETQVYRLNTQEFSPDFDSDGY
>A0A423XZ84|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cronobacter malonaticus|TrEMBL
MESLLNLPVAGGASVRILQITDTHLFAGKNDTLLGVNTWESYQAVLAELHAEQRECDLIV
ATGDLAQDHTPEAYEHFATGIASLPAPCVWLPGNHDFQPAMYSTLQDAGISPAKRVFAGD
NWQVLLLDSQVFGVPHGELSDYQLEWLERMLQAAPERHTLLLLHHHPLPSGCGWLDQHSL
RNAQALDDVLKRYPQVKHLLCGHIHQELDLDWNGRRLMATPSTCVQFKPHCAGFTLDTVA
PGWRWLNLHPDGSLTTEVCRLEGAQFRPDTASEGY
>A0A8B2WMU2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNEFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNVAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELYSDGSIRTQVKRIQQAEFLPNMQEEGY
>A0A8D4QN13|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQAVLLDSQVYGVPHGQLSQHQLDLLKETLGKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELYSDGSIRTQVKRIQQAEFLPNMQEDGY
>A0A2S9S1T0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGKH
WQAVLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLSPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTQVKRIQQAEFLPNMQEDGY
>A0A5Y3FG22|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAVAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5U2F258|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKCVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRADTASEGY
>A0A2N7LDG4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterovibrio norvegicus|TrEMBL
MRICHLPSQHSQTVRLLQITDTHLFADPHGSLLGINTAASYKAVVEEIQAQDISFDAIIA
TGDLSQDHTAESYQRFVDGIAHWSQPCYWLPGNHDYQPEMNAVLEQSTLVRCDQVLLGEH
WQMIILDSQVKGVPHGRLTSEQLALLEQALTSYPERHALILLHHHPLPAGSAWLDQHQLH
NQDAFWLCVEKHSKVKGVVCGHIHQALDTEHAGRRVMAAPSTCIQFLPDSDDFALDSTNP
GWREISLHQDGTISSEVGRLKGMGFHPDMNSAGY
>A0A2M9GZG5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter ruhlandii|TrEMBL
MARVHTLARRNDAPAMLVQLTDCHLFGEPDTVMLGVNTDASLRAVLRQIEADGKHPDLLL
ATGDLSQDGEPAAYRRLAALLEAAPALERARIRCLPGNHDLPSAMRQELPEWSTPVSDVG
AWRVISLDTTVPGSNAGHLPDSQLDMLETALAEAPGRHTLLAMHHNPMQIDSHWHDSMMI
DNPQALFKRLTRWPQVRVLLWGHVHHEFDRRRHNLRLLATPSTCFQFSIRDGKHVVDNLA
PGYRWIKLYQDGSMATGVRRVQDALWHAAQAGPDSAQAA
>A0A7R9NBL5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Methanoperedenaceae archaeon GB50|TrEMBL
MVKDEKIKIAHISDLHITGPNFVSEWGENVIDILNSEMPEILIITGDLTDDGYVHEYELA
KTYIDRIKVKNKIVVPGNHDARNEGYIIFEETFGTRCPYYENEKVVILGIDSSQPDIDDG
HVGRENYGFIREKLSINNKVKILAMHHHLIPIPGTGRERNIPSDAGDVLKICMELGVNFV
FSGHKHLPWTWRLENTYLITAGTATSRRLKGRSYPSFNILEIPAIHADKRDKMATLKEVD
VINKKFREILRGFRALKNVETPLV
>A0A2P8B172|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micromonospora sp. MH33|TrEMBL
MLIAQLSDPHVTTGPLAAEQASGLHRALGRVLALRPRPDCVVITGDLVSNGRPDEYLALR
EVIARFPLPVHLAAGNHDDRESLLDTFGGTPYLGGGFSAHYHVDQPDGTLVVLDSHAPGD
DAGRLGDDQLGWLDGVLAGRPDVPAVVCLHHPPVAVGVPAMDAMGLTDADALAEVIGRHP
HVARVAAGHLHRPVTSAFAGTVLTTAPSTWMQVSLAMSDDSEIGWVAEPTAFLLHLVSGG
GCVTHTVQVSHAAGRTCWF
>A0A5N7JTA2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas kitaguniensis|TrEMBL
MPSVSTLNPDAPALLVQLTDSHLFAEADGTLLGMNTRESLQRVIERVREQQPQIDLVLAT
GDLSQDGTLASYQLFRQMTGAISAPARWIPGNHDEPQVMAHAAVQSDLLEPVVDVGNWRV
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPSRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEVDLERNGVRLLASPSTCIQFAPGSEDFNVSEQAPGYR
WLRLHADGRLETGVERVEGFAFTVDYGSNGY
>A0A7V8ETK7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. LD120|TrEMBL
MPSVSALTADDAVLLVQLSDSHLFAEMDRSLLGMNTADSLQRVIDLVLAQQPRIDLMLAT
GDLSQDGSLESYQRFGQLTRQIPAPSRWLPGNHDEPQIMQQAAQGSDALEPVVDIGNWRI
TLLDSAVPGSVPGYLQDDQLQLLARSLGEAPERHHLICLHHHPVSIDCAWMEPIGLRNAP
ALFAVIERFPQVRALLWGHVHQEIDRLHGDVRLLASPSTCIQFEPGSDDFKVHELAPGYR
WLRLLPDGRLETGVQRVEGYAFTIDYGSNGY
>A0A8F9TC08|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. So3.2b|TrEMBL
MPSVSIVNPDAPALLVQLSDSHLFAEADGTLLGMNTRDSLQRVIDLVRAQQPQIDLLLAT
GDLSQDGTLASYQLFRELSQQVGAPARWIPGNHDEPQVMAEATMGSALLEPVVDVGNWRV
IMLDSAVPGSVPGYLADVQLQLLAQALSEAPGRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERHGVRLLASPSTCIQFAPGSEDFNVSEQAPGYR
WLRLHADGRLETGVERVQGFAFTVDYGSNGY
>A0A5P9B3R9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. THAF190c|TrEMBL
MELSHTSKLDESSIKLVQLTDTHLFAPSNGSLLSINTEDSFRAVVDGIVNQGYEYEAVLA
TGDISQDHSAESYQKFEAGIQPLEKPCYWLPGNHDYKPNMGSVIPSAQIQCVEHVLLGEH
WQMILLDSQVVGVPHGRLSDQQLDLLEQKLAEYPQKHTLVLLHHHPLLVGSAWLDQHCLK
DADQFWDVVSQHSNVRGVLCGHVHQDMNREHLGVQVMATPSTCVQFKPNSDDFALDTLSP
GWRELELKPNGEITTEVRRLERGAFAPDFNAEGY
>A0A6S6ZKC3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter pestifer|TrEMBL
MFHVFTGLISLYVIWRFVWRLPIAKSGRILLAIAFLLIAEHHLVTRNFFGSMASPEIPAT
LLMVLGWLFGSLLLLAMLLLVRDVAGLLAYAGSRSRGRRLWAAQQWGVGAAAAAMALSAV
GVWQAVRVPDVKTIDIALPNLPPALDGFRLVQLTDLHASRLLEGPWIDAVVKKANALNPD
LMLITGDLVDGTTDARAADVQPLQALTSRHGVYAIPGNHEYYAEYQRWLTEFDKLGLRLL
LNEHVTLTHNGQPLVLAGITDIMAARYGQPQPDVAKALEGVSPADTVILMSHRPGGAAIN
AQAGADLQLSGHTHGGQILGPHLLTQLANEGYVSGQYQVGDMQLYVSNGTGLWPGFPIRL
GRPSEITQIVLRAAR
>A0A4U1BJP7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ferrimonas sediminicola|TrEMBL
MSVRAKALSFPADKQSIRIAQISDPHLFADKGAEFLGLNPWDSFSAVLSELRYEPLDMVI
ASGDLSQDHSIEAYRHFADGVRGLGVPISALPGNHDAFDRMELGLEGSGVILDRRIILGR
WQLLQLDSTVLGLPGGHLNHHRLEWLEAVLHHSSAYHTLIALHHHPLDTGCTWLDQHRLD
NGAEFNALISGFDTVKGVIWGHVHQEMDERLDHIRMLAAPSTSIQFRPQCRDFTLDNLQP
GYRLLTLNADGSIDTSINRLSGDRFQPDRTASGY
>E1V834|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9)|TrEMBL
MRLIQITDCHLHADPAARSRTGVPHRQFVRVVEEAASWRPDMVLVTGDVSQDETAASYAL
AERELARLDCPWSWLPGNHDEPARMAECRPFDESVDLGQRRLLLLDTQVPGQTHGALGAA
RLEALAERLAEDERPTLVAMHHPPVSVGSRWVDALGLVDAEAFWEVLATHERVEAILCGH
IHQAFECRRATPHGEVAIYACPATSDQFLPGAETFAVDAAALPGFRVFDLGDALSTRVER
VAL
>A0A4R0EPS2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter terrae|TrEMBL
MTLSNYNETQQDWTIIQISDTHLMNQEDLEFVDMNPEQSFHAVIEQIQQQYPNVDAIIHT
GDLAQVPVKETYTRYLAFMQRLGIPFYQIPGNHDDMDLFPFYHNQNQVHAIHFGPWSMVL
LNSAVRGKIDGWIEEEQLQQLDQILSKFQQQFVIVACHHHPFDMQSKWIDQHKLKNTGNL
TDILARHTNVKAVISGHVHQDSLNEWKNIQFFSTPSTCVQFKPLSDDFALDEEAPGFRVL
HLKANGELQTEIYRTEKASQKINVEISGY
>D3VCR5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / CCUG 14189 / LMG 1036 / NCIMB 9965 / AN6)|TrEMBL
MESLLEVPVAEGATARILQITDTHLFANKGDSLLGVNTYNSYHAVLDTILEQNLDIDLIV
ATGDLVQDQTIEAYQHFAEGMARLPASCVWLPGNHDYQPAMVDTLAAAGISPSKQIFIGQ
HWQLIMLDSQVQGVPHGELTDYQLEWMKKCLDEHSERQAIVMLHHHPVPSGCTWLDQHSL
RNAPELSEFLKGQTQVQAILCGHIHQEIDDMWNGIRVLATPSTCVQFKPHCTNFMLDTEA
PGWRYLELSVTGKQEARLQTQVHRLKSNEFCPDLDSDGY
>A0A509DU52|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Thalassocella blandensis|TrEMBL
MSHGQVKLAAAELTAGKQGVVRIAAVGDLHCRENSAGLLSPLFNYANQRADILLLAGDLT
DYGLPEEANTLVDELAEVQIPVVAVLGNHDYESNQADQVKAILSNAGVKVLDGDAVEING
IGIAGVKGFAGGFGRASLGPWGEEPIKHFVNVAIDEALKLETALSRLRTPVKIALLHYSP
IKATVEGEPEEIFAFLGTSRLEDPLIHHPVDVVFHGHAHRGTPAGETANGIPVYNVAKPL
LESQHKDKPALHFIEFGKNKVMARESGTLK
>A0A2M8S214|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Conservatibacter flavescens|TrEMBL
MLSSFSLNTADSVVRFLQITDPHLFKEENSDLLGINTLESFKQVLTEILQQDFPYEFVLA
TGDIVQDSSDEAYQRFVQLVQCLEKTVFWIPGNHDFQPKMFDYLTGQYGNINPNKHILAG
EHWQILMLDSQVFGVPHGQLSQYQLDWLVAKLKEYPNRYSLVVLHHHILPTHSSWLDQHN
LRNLHDLMEALSPFEKVKGILHGHIHQQVDDYWHGYKVMSTPSTCIQFKPDCHQFTLDNL
QPGWREIELHADGNIYTQVKRIQQKTFLPNFKEEGY
>A0A4U7KFS2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium polonicum|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKVQQDAFDLIV
ATGDLAQDHTLQAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKNQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSAVLDRYPKVNTVLCGHIHQEMDCDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A1I7BEG7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kosakonia arachidis|TrEMBL
MESLLNLSLAGESRVRVLQITDSHLFAEKHETLLGVNTWESYQAVLEAIQAQQRPCDLIV
ATGDLAQDHSAAAYQHFAEGIARFVAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
HWQILLLDSQVFGVPHGELSEFQLEWLENKLSDSPERHTLLLLHHHPLPSGCSWLDQHSL
RNAGELNNVLQRFPKVRHLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLYDDGTLYTEVCRLESTLFRPDTASEGY
>A0A418U868|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGMPHGELSEFQLEWLERKLADAPGRHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A509EAD6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium symbioticum|TrEMBL
MASSHSPGSAMRDPFVVLHVGDLHLTGSGQANVRDFAAILDEIAGLAPRGAFDFVYLPGD
HAEDGTAAQYAILEGALNRHPDLPVRLIAGDHDRQYGTMIDFDATFARIAGSPRGGTHRA
RHNHLPRPRAPGSVTQYYYAETIGGVRCLFLDMVSAGYGEKGFGLDFRLGPCQLDWLGRK
LKKAAAAGLPCAVFAHTYPDDLRVPEERIALAGLIRGYGVRLVEMGHTHYNELAHDGRTL
YAAARSVGQNEDGSVGYAVAAIDGAVTSWRFKPLDRALPFVMITSPADRRLATAALDSTD
GRIEVRALVLSKAAQSAWRCYVRVDDGPAQPMKPDGPRAVHAWIDWPEGARRLSVEVTDG
TATVGATMPNTDIDVIEPVRRSFVPPPAPQRPGSDTFRLPAWPVKGVRGDQLGPNRAGRK
W
>A0A8I1EIF9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MSPPDQSRPVHVVQLTDAHLFADPAGSMLGLKTRDSLRHVVAQVRREQPLVDLLLCTGDL
SQDASVASYEAFRELTAPLAVPTRWLPGNHDEAQVMAQVAPELVQAVTDIGAWRVVMLNT
AVQGATHGFLQDDQLAVLEAALKEAGERHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDI
VEGYPQVRALLWGHVHQEWDEVREGRRLLATPSTCIQFAARSEDFQVSEEHPGYRWLRLH
ADGRLETGVERALDFEVQLDFDSPGY
>A0A5E4XIQ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea cepalis|TrEMBL
MRLHILSDLHLSVAPLAIPEVDADVTILAGDIGRPAQAIEWAKALGRPVIYVPGNHEFYG
ATLAGTLADLRHLSAGTNVHLLERRSVVIGGVRFVGTTLWTDFALYDADGKHDDVVEESR
KFVRDFTRIRVGDPAVPWAELPCFSPDDCAALCRENVAWLARVLAAPHDGPTIVVTHHAP
TPQSIHPRFAGSLVNPAFISDLTSFVESSEAVLWIHGHTHDSFDYRIGPTRVLCNPRGYC
FEGRVENAAFDPTLTVRV
>A0A5E4XJ37|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea cepalis|TrEMBL
MKLHILSDLHLSVAPLAIPEVDADVTILAGDIGRPAQAIEWAKALGRPVIYVPGNHEFYG
ATLAGTLADLRHLSAGTNVHLLERRLEVIGGVRFVGTTLWTDFALYDADGKHDDVVEESR
KFVRDFTRIRVGDPAVPWADLPFFSPDDCAALCRENVAWLARVLAAPHDGPTVVVTHHAP
TPQSIHPRFAGSLVNPAFISDLTSFVEASDAALWIHGHTHDSFDYRVGATRVLCNPRGYC
FEGRVENTAFDPTLTVRV
>A0A539CQG5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Beijerinckiaceae bacterium|TrEMBL
MYDLGGNRHRLDAQRRRAKILATSWHRSGGSGRKGGRGFQLPANFRQPCRFQQTGQSGRA
RDLEGSDRQGEWPSGQTRLHDPHRRFTHLSKAGQFDDAEKVIGEAKLDVHYVPGEHDLVD
EDNGKAYLGRFGKNTKGTGWYSFDAGGVHFIGLVNAANLKAGGMGSLGDEQIAWLTDDLK
GKGASTPVVVVAHIPLWTVYADWGWGTEDSARALALLKRFGSVTVLNGHIHQLMQKVEGH
VTFRTARSTAFPQPAPGTAPSPGHLLVTAEKLRTVLGIKRRGQARQKSPRDHRYTA
>D2ZKG6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cancerogenus ATCC 35316|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRRCDLIV
ATGDLAQDQSSAAYQHFSEGIASFSAPCVWLPGNHDFQPAMYSSLQEAGISPAKCVFLGE
QWQVLLLDSQVFGVPHGELSDFQLDWLESKLAAEPARHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLVKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCDSFTLDTIA
PGWRWLELHADGTLTTEVCRLSGAEFRPDTASEGY
>A0A674EJF0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmo trutta|TrEMBL
MYAKYAIIYPLYSTQCHICTGVIPPSLSHFLSLPSLCVQFKRMLNRELSHLSQMSRSGNQ
VSEFISRTFLDKQHGAERPCPQMQKVKMDKKNAKPMCQMSGVKRLQHSTSLSNSNIPRFG
VKTGTDDKLATELEDINKWGLNLFKVTELSGNRPLTVIMYTILQERHLFKTFKIPLDTFI
TYLMTLEDYYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIYDVD
HPGVSNQFLISTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKM
VIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYKDRIQVGCYFTYRHPAGKTG
RNYVFCIVMVRLYIDCKMLGLSND
>A0A8C3SUE2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chelydra serpentina|TrEMBL
NHITWSGRWGGSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYD
LSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLPDRAPNK
>A0A377I0E7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus parahaemolyticus|TrEMBL
MNTFYPLEPKTSVIKLLQITDPHLFSDTTKDLLGVNTHASFQAVLDEIQAEIQTQAVDFD
AILATGDLIQDHQSEGYLHFAEMIRPLAKPVFWLEGNHDQQPQMSLLLGKFDYIRPEKQI
FAGDHWQILMLNSQVAAAPSGYLSKGQLAWLNQKLSENPERFTLVVLHHNILFTHSAWLD
QHSLKNSDTLAEILALYPNVKAILHGHIHQEVDAIWNGIRILSTPSTCIQFKPNCDDFTL
DNLPQGWRELSLFEDGRIETEVKRLKTQAFLPNFDSQGY
>A0A224YRH7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rhipicephalus zambeziensis|TrEMBL
MGCTQSAIQRRAGGRAGRGGPATPVPTAAGVPPSASDLSAATNNSASNNRCRAPPSASES
QPQHRNSRPQCLEGARPLFRRATNWEVVTERNVPLCAMLDGAPDDGRKGTVALKFGSMYL
TVPSVKVMFVFGKEDAQYNALKWAADKMHYECTLSSTSEAAIDNYLNGQPHLVFVDARSK
STIDPVTLCRTLRGFRGSQFTCIIAVVKKGLADKEEAAVIPLLKCGYNRWFTETCSLGVC
LNEMIQIEHNDLINLWKLRASEALFSALHYARDGVIVTGAAHEIQYMNRAAEKLVGYSVE
EMLGVDAQELHRTDSLKTEVATTICTQLKKGKEWEGTLFHKRKSGECIPMWSKIAPVEIH
TGKSDHVVYIKECPFFLEKPFSPDAVGMNRRQSFAKFHAMTLEAPITKVINMLVSTQENS
SAMVAQALDRVIEILRSTELYNPQLGVGQGKSEDQMTSDLVTGLINTGQKPTGVRRLSHE
TSLMKVNVVNATASSGVLPSLQTAPSKIKDLLENDVKWEFDIIELETLTGRRPLIWLGLS
IFSKLNVHTSLECDDATIRNWLQLVESHYLENPYHNSTHAGDVMQATAYFLLKLRKKDIF
DPLDEAICLISAVVHDIDHPGKSSAFLCNSDHELAILYNDRSVLESHHAAFAFKLTLSDE
KVNIFQKLDRDVYRSVRLSIIDMVLATEMTKHFEHLSKFLNAFQKPMQEEEGFEAEPLQE
HGESASLRSAENIILIKRMLIKCSDVSNPARPINLCIQWAHRIAEEYCAQTDEEKRLGLT
VVMPAFDRATCSIPNSQTGFINYFVRDMFRAWSDFGEFPELMEYIEKNYIYWKDKEPSSS
QQGNR
>A0A1V3TTE4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurellaceae bacterium 15-036681|TrEMBL
MDDVYLFPDSKPVVRILQITDPHLFGSDDGQLLGVNTAQSFQAVLDAILKQPFEYDFVLA
TGDLVQDHNREAYHRFAKMVRPLEKDIFWVEGNHDIQPQMSNALAMYAQIQPAKHILAGD
KWQVILLDSQVYGIPGGRLSQEQLDFLYKSLSQYPERYSLIVLHHNVLPTNSAWLDQHIL
ANVDEFAQVLQQFPNVKAILHGHIHQEVDRKWLDYRVFATPSTCIQFKANHDEFGLDPRP
QGWRELNLMPDGTIETLVRRLGHSEFSPDFGAKGY
>A0A1I4Z4K4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus japonica|TrEMBL
MESLLEVPVAEGATARILQITDTHLFANKGDSLLGVNTYCSYQAVLDMILKQNLDIDLIV
ATGDLVQDQTINAYQHFAEGIARLPAPCVWLPGNHDYQPAMVDTLAAAGISPSKQIFIGQ
HWQLIMLDSQVQGVPHGELTDYQLEWMKKCLDEHSDRHTIVMLHHHPVPSGCTWLDQHSL
RNSPELSECLKGRTQVKAMLCGHIHQEVDEMWNGIRVMATPSTCVQFKPHCTNFMLDTVA
PGWRYLELSVTGNKEAKLQTQVHRLKSNEFCPDLDSDGY
>A0A0M3G776|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus haemolyticus|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENHEFDVILA
TGDLVQDSSDEGYTRFVEMMKPFDKPVFWIPGNHDFQPKMAEFLNQSPMDGAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAEFLPNMQEEGY
>A0A195D1Y8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyphomyrmex costatus|TrEMBL
MKDQIPYHRTVKNVEVSPRARRRAKIYKLLESIYLDKEEPKGPQDLSNYLLTTNVPSIVK
ILLVFSKDDQQMDILASTARRLGWSVSVAKDAEKALELFQNRAHELVIIDHRGHHAAEGD
AICRAIRSSPVYHNSVIIALVKKSYFMLDEKDHIVALNLLEIGFNRALMECSHEGILINE
LVGIYTSSLLPKTQLAAAHALYLALDRCRDMVHVTNDKNIVQFLNKVSEKLLGYKVEEMI
GRNLSEIVYYENFPLMEQQLSKGREFEGNMNCKRKNNQMITINCRIIPFCITLKKPSHYV
YVYDTTYLSENSAPISPISSPLHPPLKTNMTNARKSSDVRSGISEDKGRRRSSLQKLHTL
QLEAPITKVITLLSNAVTDTTNPETAAQIDKAIDILKTTELYVPHLKEDRAMCSDPVATD
LVGALLASPRTAWESRRSSSDSARLSTIKAITGPANSRVQVKNFRGPQEITEVLDKSLDW
DFEIFKLEVLTERRPLVFLGLTIMNLYQVPATLHCDERTLQNWLAIIEHNYNAENSYHNS
THAADVLQATARFMQSKRLKEILEPLDEIAALIAAAAHDIDHPGRSSQFLCNANSRLAIL
YNDLSVLESHHAALTFKLSLSDDSVNIFKNMERDAYKLLRQNVIDMILATEMTKHFEHLA
KFMNVCSARIGDGQETYSDSLDMTVVLQPDNVILVKRMMIKCADVSNPTRPLKCCVEWAR
RIAEEYFNQTDEEKKLKMPVVMPMFDRMTCSIPKSQIGFVDYIINDMIEAWDVFIDMPEI
VGYMRHNYEKWKEYNEQGISTLQDVEKLQQHPEMQILRLS
>A0A5N8UUD6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. YLB-07|TrEMBL
MLKEAISYSIEEKASVRIVQVTDPHLFADPNSQLLGVNTAKSLESVLNTIKAVDYPADLM
LATGDISQDYSGESYHNFVRAITPLDMPCHYLPGNHDDPRVMSLHMQGSKIFGQRRILAG
NWQIIMLDSTVRGKPGGHMSDREIEIIKSAVADQPERHVLLVMHHNPILVKCRWLDQHWM
DNGSEFIEQVAQIPQVKGLLWGHVHQELDIEHQGMHGIIHLMSTPSTCIQFKPLSSYFAL
DAQQPGYRLLELKADGSMITNVYRVPGDKFSPDRNVSGY
>A0A6P8MHQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bombus bifarius|TrEMBL
MASPSNDSFFPNEGLNILDDILLSNGKTEYDVLRRRSSFEDVAVDDDENADCSALKGPQN
IEAHPLTNSVPSLIKILLVFPKDDQQMDVLATTSRRLGWSVSVAKDAEKAVEFFQNRGHE
LVIIDHRGQRAAEADTICRYGELFFKNQPNSSGVRLYILINTIYFRAIRSSPAYHNSIII
ALVKKSFLMHGEKDKIVTLDLLETGFSRALMECSHERLLINELVGIYASALLPRTQLAAA
NALYVALDRCRDMVHVTNDKHIVQFVNKISEKLLGYKTSEILGKSIADIVVYDNFVLMEQ
HISKGREFEGNMNCKRKNNQMITISCRVIPFSISLKKPTHYIYIYDTTYLSENIGSLSPT
PSQSVYSRGNMIVSQRRTSDMKSSEGRRRSSAHKLHSLQLDAPITKVISLLSNAITESTT
PDTAAQIEKAIDILKTTELYVPSLREDTDPVTTDLVGALLASPRKAWESRRSSVESTRVS
MSKAFTTTTSSRMQIKSFRGPQEIAEILERCLEWNFDIFKLEILTEKRPLLFLGTTIMNM
YRVPARLGCEEKVVQNWLTVIEMNYQSRNSYHNSTHAADVLQATARFMQSERLQQILEPL
DEVATLVAAAAHDVDHPGRSSQFLCNSDNKLAILYNDLSVLESHHAALTFKLSLSDDNVN
IFKNLERDTYKQLRQTVIDMILATEMTKHFEHLAKFMNICSARMMDSPQLDDYTDTVDMS
VVLQPENVVLVKRMMIKCADVSNPTRPLKCCVEWARRIAEEYFNQTDEEKRMQLPVLMPM
FDRATCSIPKAQIGFVDFIINDMVEAWDAFIDMPEMVGYMRQNYEKWKEYNDRGISTLPD
IEKIQELPELRIYHLPS
>A0A1V3I7B5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rodentibacter heidelbergensis|TrEMBL
MKNTFVYQAEKPIVKLLQITDPHLFKDEKNELLGINTQASFAQVLKEIQQENREFDVILT
TGDLVQDSSDEGYQRFVKMVKPFGVPVFWIPGNHDFQPKMVENLNQPPMERAKHILLGAH
WQILLLDSQVYGVPHGELSQYQLDLLKTTLEKYPEHHTLIVFHHHVLPTNSAWLDQHNLR
NSHDLFDILLPFKNVKGILYGHIHQQVDSFWQGYQVMATPSTCIQFKADSQHFALDEAQP
GWREIELHPDGLIVTRVKRITQTRFLPNMEEEGY
>A0A8C9E0Q5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Phocoena sinus|TrEMBL
AFQGSRSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKS
MSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINK
ATLTGKKDLGDYSSHI
>A0A6I9P6M0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Notothenia coriiceps|TrEMBL
MSSNELSVDMDSCIRTFKEHMHLELEPPKIPGVGGGKRGATSPKLSPRSSPRLFRKLMVN
KSIRQRRRFTVAHTCFDVENGPSTSCSPLDPQASPGSGLVLHTNFPGHNQRRESFLYRSD
SDYDLSPKSMSRNSSIASELHGDDLIVTPFAQVLASLRSVRNNFTVLTNVQCASSKRSPA
ATQPPITRVCLPDEA
>A0A7D6U642|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter roggenkampii|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEKRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQEAGISPAKCVFTGD
QWQILLLDSQVFGVPHGELSDYQLDWLETKLAAEPNRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLAKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLHADGSLTTEVCRLAGAQFRPDTASEGY
>A0A5E4YFB2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea commovens|TrEMBL
MSQSSQASQTSDAPPGASHTHSKPSKRTLPARPRWLMLAIIALLHAYIGWRLLTPLPVAI
GWKVLGGLWLAVSTVLIPLGLMSRAIQKEPLATLLTWTGMTAIGVFSSLFVFTLLRDVVL
GVAMAFSALDAQLVTRSAVIVLILTAVSTVLGFYNARRLARVVDVDVPIANLPSELKGFT
IVQLSDIHVSSTIRRGYIEAIVEASNALKPDLVAITGDLVDGGVPALRDHIAPLGQLTSR
HGTYVCTGNHEYYSGAPAWVAELRRIGLTVLENEHVVLDHEGASLTVAGVTDFTAHQFDP
EKRSDPQAAIDGAPDGVPRVLLAHQPRSAPAAQEAGFDLQLSGHTHGGQFWPWMYFVPLQ
QPFVHGLHRLDRLAIYVSRGTGYWGPPKRFGAPSEITRIRLVPGKV
>A0A1C7W9S4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia sp. 14-2641|TrEMBL
MESLFRLPVASGAKVRILQITDTHLFAGKSETLLGINTYASYHAVLDAVIAQQRECDLIV
ATGDLAQDHSQAAYRHFADGITRLPAPCVWLPGNHDFQPAMVDALAAAGISPSKQVLLGD
NWQVLLLDSQVFGVPHGELSEYQLEWMERCLEAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHTLAAVLWRYPKVNTLLCGHIHQELDLGWHRRRLLATPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A4R0F979|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. ANC 4216|TrEMBL
MTLYQHNEDQQDWTIIQISDTHLMNQEDLEFVHMNPEHSFQSVMQQIRQQYPNTDAIINT
GDLAQVPVAETYSRYLSFMQRLGIPFYQIPGNHDNIDLFPFYQNKDEVQAIHFGRWSFVL
LNSAVPDRIDGWIEQEQLQQLDILLAKLQQQSVIVACHHHPFAMQSKWIDQHMLKNTENL
TDILAKHSNVKAVIFGHVHQDSCHEWQHIRFFSTPSTCVQFKPFSEDFALDNEMPGFRVL
HLKANGELETQIHRVQTARQQINGEISGY
>G4A8P3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aggregatibacter actinomycetemcomitans serotype e str. SC1083|TrEMBL
MLNTYKYDTRQEVFRVIQITDPHLFKDATGELLGVNTQESFSQVLSEIRQQAYDYDLVLA
TGDLVQDSSEEGYLRFCESVKSLEKTVFWIPGNHDFQPKMFDILKRDNICDKKHILLGEN
WQILLLDSQISGVPHGQLGQYQLDWLMAKLKEHPQRYSLVVLHHHILSTHSAWLDQHNLR
NAHELAYTLAPFNNVKGILYGHIHQQVDGEWNGYKIMATPSTGIQFKPDSNTFALDTAQP
GWREIELYADGRIETRVKRIQHKTFLPNLQEEGY
>A0A8C5J241|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Junco hyemalis|TrEMBL
MDRRPQRQPDYMSVCLFAEEPYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKVTKL
NPTCLNQALPSPALRLLRKHSHGMCAFLEEEKEQVHRGSDTRP
>A0A7J0AUN2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MASAMVAVSLLASCSDDVVAERRPGADSDPLTIKAQFGKNLVGRVTVDGQPRQGVVVSDG
INVMTTDANGEYQMYTTGRQHVFISVPADCELPTLLGDPKFYKTLDYSDAAIIQRDFRLV
SIPKKTEWTLFTMADPQIGNEKDITDFVEMIPRMAEFASSLPSNVYGISLGDIVWNKPEY
FDTYAKEMRNIPVPVFSVIGNHDHNEGIKNDTESDKDFRDALGPTYYSVNIGDCHLVVLD
DVFYRGVNGRNDYTGTITEAQLEWLEKDLSYVDPDKAVIIGLHIPTKRRNSSTHVTNNQA
LYDLVKDFREVQILSGHSHNHYTTTIASNITETTFAAVMGAYWYPLCNDGSPRGYGALDF
KGNTLVNKYFIGDGCDRDYQMKLYRPEDAVLWNPSKNAGDPYDKILANIFCWHEDWTVEV
KEDAGSWTVLPASARLIPSQNGGKCWDPDVRKCLVDGVIPANHGGSAPENNNDHMFLYTP
QPGWQSVSFRATDSFGNVYTETITNN
>A0A7J0AUZ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MKIQYASDLHLEFHENSRWLKENLLAAVGDVLILAGDIGYLGDDNYRRHPFWDWCAESFR
QTIVIPGNHELYKSFDINDLHEGWQQEIRPNVKACYNCVIQLAPNIDLIASTLWAKIHPY
DEYQTERGVTDFHRIRNGQFRLSAQRFNQEHERCREFIERSVAESQAKHIIVATHHVPSF
ELMADEFKGSPINGAFTSELGDFIASSRIEYWIYGHSHRNINKAIGNTRCICNQLGYTFH
GEQADFHRDAIIEIITVR
>A0A7G9Z695|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methanosarcinales archaeon ANME-1 ERB7|TrEMBL
MNRKSKAKKLFEDTQTVSPIRALYVIAILAISVLVVPVCAQPGNLGHNLAYPELPQKDVT
PDYLLVDGVDVTVDAVAKEATLQFDTIVPTSKAIVDYGLFVPQQEIKVPQYRREGIEELV
GENTAHTVSKINIGKFESSRYDICNFEEDGGVICYCIELYNPEKATSVFYDGRFRVDGDY
NIVPCVTEGPFVDLVTTDSAVISWETDAPTTAAVETDSKSYTDDVSNTHHEIAISGLAPN
TEYKYDVLVDGVKDIKTYKFKTTPAAASTKFEFALMSDSRAGVGGGERSFAGVNYHKLSR
FMTDAYNNGADVILFGGDLVNGYTTSLEDYRMQLKAWKDATEQIGCYIPIYEGMGNHEAV
IDVYDDESKYGIDFDKQDADGDKSSETIFAAEFVNPANSFPDPENTSAPSYEENVYYFDY
GNTRFIAFNTNYWWCNYPEDFGGNLEGYVMDNQLEWIKDVLDDTKNNPSIEHVFMFAHEP
AFPNGGHLQDAQWYSGGDSAENEDYVGNPLDRAYVVERRDELWEAISQNGKVVAVFFGDE
HNYNRMSVDSETPVHLDGSANANFTNSVWQIVSGGAGAPFYAQEDTPWSGDVEVFYPSKH
YCMVSVDGDKVSLKAISDSGEIVDECVLCG
>A0A659LQ12|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. E2593|TrEMBL
MESLLTLPLAGESRVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADSRFQPDTASEGY
>A0A193K9Q0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio breoganii|TrEMBL
MEPQIVATEETVQLVQITDTHLFADDEGCLLSVNTGQSFIATVNDIVERNVEFDAIVATG
DISQDHSAASYTRFADGIKPLEKQCYWLPGNHDQKSNMVTVLPSPQIQEVGHVLAGEYWQ
IIMLDSQVEGLPHGYLETDQLELLDNKLAEFPERHTLVLLHHNALPIGSAWLDQHKLQRA
HQFWEVLGRHQNVRAVLGGHVHQDFEKEHNGVRVLATPSTCIQFKANNDEFALDTLSPGW
RHLQLHKDGQLESQVHRLEEGCFIPDFEAEGY
>A0A752MGN0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella gallinarum|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A7R8H615|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lepeophtheirus salmonis|TrEMBL
MPLDPKVSKKKSSSISSGSTAPKSIVVGSRLNIGRCYSSDAGLPQMTGYHHANTTLGMSP
TSSSTVSGISLYQRQIICAAAAATENSLLRTSNTSISSSNSLYYHTLKRNSFDVDHGSSP
GRTPLEGFPGLVLQSSGLPQRRESFLYRSDSDYEVNSPRSISRASSIASEVGHGDDLIVT
PFAQILASLRSIRANYIHITNVPNRGRNDRTPSRDPGSFNPTTASYSRPNLTDDAFVRTA
METLEELDWCMDQLESMQTHRSVSDMASNKVNNTE
>Q07XU9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella frigidimarina (strain NCIMB 400)|TrEMBL
MLKDAVHYSVAENEPVRLVQVTDPHLFADPEGQLLGVNTAQSLQAVLNTFIATQYPANIL
LATGDISQDYSPESYQHFVQKIEMLDLPCHYLPGNHDDPRLMSLRMQGEKVFGQQRIIIG
NWLILMLDSTVRGKPGGYMGEQQFALIEAAIKATPDKHVLLVMHHNPILMQCAWLDQHCM
MNGEDFLQRTSRYPQVKGVLWGHVHQQVDNIHRGPHGPIPLMATPSTCIQFKPLSSYFAL
DHRQPGYRLLELAGDGSIRTNVYRVPGNRFAPDNEASGY
>A0A377IYU7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus pittmaniae|TrEMBL
MLSSFVYQTDKPVVRLLQITDPHLFKDTNKDLLGINTQASFAQVLTEIQASDFDYELILA
TGDLVQDSSDEGYRLFVEMTSGLDKPLFWIPGNHDFQPKMVEFLNHHPINRLKHLLIGDN
WQILLLDSQVSGVPHGELSQYQLDWIGAKLAQNPSRFSLIVLHHHLLPTNSAWLDQHNLR
NSQDLLDVLSPFKNVKAIMYGHIHQAVDDMWFDYRVMATPSTCIQFKPDSNHFSLDTLQP
GWREIELYNDGHIETRVKRIQDAVFLPNMREDGYE
>A0A7Y3QVQ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. 3-2(1)|TrEMBL
MNVSPTLDNSDSIKLLQITDTHLFAPDDGSLLSVNTVDSFHAVVAEICAQHVEFDAILAT
GDISQDHSAESYLRFSRGISSLEKTCFWLPGNHDFKPNMGAVFPSEQIQQSEHVLLGEHW
QMVMLDSQVVGVPHGRLSDQQLALLDEKLSTYHQRHTLVVLHHHPLLVGSAWLDQHSLKD
SDAFWNIVTQHRNVKAVLCGHVHQNMDKLHHGVRVMATPSTCVQFKPNSDDFALDRTSPG
WRELTLSADGQMETQVKRLANGAFQPDFNANGY
>A0A5E4WZI7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea iniqua|TrEMBL
MSGRTTDEANQGAGSSGSSGGHGNAGDSGIAGTADTTAVSRAELAATGRGEPTAPSASPG
MSRRRAMACLAWAGAGILWTLDGGVPRGVSFGTPALAATDAPAGNALSFVQISDSHIGFN
KAPNPDPASTLQSAIERIRSAPQRPAFMLHTGDVSHLSRPAEFDTAQQIVTGAGLETHYV
PGEHDVIGDDGRAFFSRFSPDTKGLGWYSFDQNGVHFVALVNVLNLKAGGMGYLGDTQLA
WLANDLKGRSHSTPLVVFTHMPLWTVYPAWGWGTDDGDRALALLRPFGSVTVLNGHIHQV
LQKVEGNVRLQTAMSTAFPQPAPGDGPGPGPKQVDPSQLRQTLGIRRVDFTALDGTPLLA
DTTLAS
>A0A836JHQ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acromyrmex insinuator|TrEMBL
MGCKISIPKCMKDKVEQEKSISSETSSSSIVISDTTEPDRDEDSLYLAFDTYKSHNFTEE
DDQKVEQHKTDAFEIVAEKNEKTPFEDNTNDENGDYLTIKGPQDFSNYLLTTNVPSIVKI
LLVFSKDDQQMDILTNTARRLGWSVSIAKNAEKALELFQNRAHELVIIDHRAHHADDGDA
ICRTIRSSPVYHSSVIIALVKKSYFMLDEKDRIVALDLLKRGFDRAMMECSHEGILINEL
VGIYTSSLLPKTQLAAAHALYLALDRCRDMVHVTNDKNIVQFLNKVSEKLLGYNVEEMMG
RNLSEIVSYENFSLMEQQLNKGREFEGNMNCKRKNNQMITINCRIIPFCITLKKPSHYIY
VYDTTYLSENSAPISPISSPLHPPLKTNTTNARKSSDVRSGSISEDKGRRRSSLQKLHTL
QLEAPITKVITLLSNAVTDTINPETAAQIDKAIDILKTTELYIPHLKEDRAMCSDPVATD
LVGALLASPRTTWESRRSSSDSARLCAIKAITSPNNSRVQVKNFRGPQEIMEILDKSLDW
DFEIFKLEILTERRPLVFLGLTIMNLYRVPATIHCDERTLQNWLAIIEHNYNAENSYHNS
THAADVLQATARFMQSKRLKEILEPLDEVAALVAAAAHDIDHPGRSSQFLCNANSRLAIL
YNDLSVLESHHAALTFKLSLSDDSVNIFKNMERDAYKLLRQNVIDMILATEMTKHFEHLA
KFMNVCSARIGDGQETYSDSLDMTVVLQPDNVILIKRMMIKCADVSNPTRPLKCCVEWAK
RIAEEYFNQTDEEKKLKMPVVMPMFDRLTCSIPKSQIGFVDYIINDMIEAWDVFIDIPEI
VGYMRYNYEKWKEYNEQGISTLQDIEKLQQHPELQILRLS
>A0A452IHC4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gopherus agassizii|TrEMBL
IFQDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSI
ASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLPDRAPNKRSPMCNQPSINKAAITGKR
D
>A0A091QBC8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Merops nubicus|TrEMBL
FDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSS
LPSEQHGDDLIVTPFAQVLASLRSVRNNFTLL
>A0A5E4IC60|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKKLKLQIVASFLIFFIINGIVFAGPIQSHITEPVIFINKNQSNSDFYFVHITDTHVVSK
LYDHNEIRKNWLISLLDYISSFDKPPAFVVITGDLVEWGEGFLGALNYYALISCFYKNNT
QLYADKYCSIPVYFTPGNHDYYPNRELYNYHLFIDRTHINDNDRYEITYENLSLFFMNSG
PNSYAKPSDCTNSLSVGLTNDDIVWLNEKLNNCTTNKKIILMHHPAINIRNDKGELYDVF
IHNREKFIKLCENDDVDAVLAGHTHDPRVFDAEEHLYENLPINSSKYPTLFVQSDDCKEG
VHYRNISIVHNDIWIEQSQEINLTYFSFLKTDY
>A0A674HHB2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Taeniopygia guttata|TrEMBL
MLPTAHCSPGASPATSPRNSPVLFRKLLMSQSIRLQRRFTVAHPLCFDLENGPPGRGTLD
PQASPGAGLVLQGTFSHGQRRESFLYRSDSDYDLSPKAMSRNSSIASDLHGEDMIVTPFA
QVLASLRTVRSNLSHLQDRAGIKRGSSSSLPSASKASLCGECRRGRCWADLGTSWLSPCP
QAVSCRALGVQHPLPAQTKAELRLCPLGSMSGFRQLLPPLAAVEKLRLTSKLPLIKAGGA
RGPAGARLPPGLAVTPRDSVARRVPGLPPRGDSVRGRAHRPGMSDPHPRVPPCPPPPPRS
GGAASPPGLGWHRVPRGGWPRCWQVPCQAGGCPQQKMPSRSSRGRPWRSWIGAWTSWRRC
RPGTRSARWPPTSSSGC
>A0A3S5XTE3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lelliottia amnigena|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAENRHCDLIA
ATGDLAQDQSAAAYQHFATGIASFSVPCVWLPGNHDFQPAMYSTLHDAGISPAKRVFVGE
HWQILLLDTQVFGVPHGELSDFQLEWLEQKLAAAPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLSKYPHVNNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLQSATFRPDTASEGY
>A0A1C0U316|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus australis subsp. thailandensis|TrEMBL
MESLFELPVVEGTTAKILQITDTHLFAGKEDTLLGINTYRSYHAVLDAILEQKTDIDLIV
ATGDLAQDQTLKAYQHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILLGK
YWQLLMLDSQVQGVPHGELSEYQLEWMKKCLDEYPERYTVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQGYSRVKAMLCGHIHQELDIDWNSIRMMATPSTCVQFKPHCTNFMLDTVA
PGWRYLELSVTDKGEFGLITQVHRLESDEFCPDLESDGY
>A0A6M0C698|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Okeania sp. SIO2H7|TrEMBL
MIFQPPVLVAQITDTHLFADSIQGKMYGVPTERSFVKVLEKLKQLQPQPDVLLLTGDLSQ
DETSQSYQRLASLLSPLNIPTYWIAGNHDNLPTMERVLSSAPISAKKSFEMGGWNFFLLN
TNVPGCVYGEISPESLEWLEYNIKMTGNKPVLIALHHPPVKINSEWMDKILLHNPENFLS
IINRYPQVKIVLSGHIHQEFAKEINGIHYLSTPSTCIQFEPGNYKFFLDKQPPGLRLLTL
YPDGNYTTKIERINYIYECDMAASGY
>A0A5W0X644|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Typhimurium var. 5-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A6S7F3A0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter insolitus|TrEMBL
MTNSRFSREPLGARLFSFAVVADTHVNESEDTCASPFATNARANARARHVFADIASLAPA
PAFTIHLGDIVHPVPSMPSFEEAASRFKAIAGQIDMPLHLVPGNHDVGDKRIDWMPADIV
CDDYLDKYRQVFGPDYYAVDHGSVRFLFLNALLFNSGLPADEAQRAWIDEQLASAAGRVF
VSLHYPPYLHDAQERGSYDNIDEPGRGWLLSRLADPRVEAVFAGHVHNFWYDVIGSAEIY
MLPSTAFLRHDFSEFYRVPPADEFGRGDVEKFGYFIVDVHEQGHVAKLIRTHGAMRGEAE
PGRAAARALPTVHTKTAACDGIAVEMRHPWAEIVEIPCTGGVQEFGRKLARNDYPLMSMW
EMGLRTLKIPVQDLRDDKTLRRARLMSDVGHRFVLTSLGLPDARLLQQAREHGIAISAIE
VNLNAQALDEAGAALQRLREHTSARLIYCKIRTGADDAHFDGKHYSHFVNTGLRASELEA
AQAALLPHFTQKNLDGFTVRLDWGSDLVATHLQLARQARDWGASVNVGVKLADRLAAANT
DDIAIAALVAEAFLAARTSDAVSYSFDTFMDVDRGYFPRNGLIDRRYDPRPAGLALAALN
AVFADQAADTGSVERIDGETGARLCRYLSGEQVYELAYGSGPALNRHVQGGAFKRVIDLT
AQRVLQERDDWTDYARRHLPDQALLLIQRN
>A0A2S9Y844|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enhygromyxa salina|TrEMBL
MRCRPTVCLLLGLSCMCQCTRVDGGADDDRELERFRIVVLADPHVPDPNYEGPEANELDT
ESILAAHQRLLDARARINAMDPAPDFVVILGDLLHTHYPYDEVQDYYDQPSAFSVAAELL
DGFEVPVHLVFGEHDYGVPRIPREDSHVLFAHFFDAAPHTAFEHHGWKFILANSQLGATW
DASSDDYDPARGSYGREQLDWIADHLFDRMPTVFLSHFPIPFDTAVFENLESPSRDIFTL
MTDHADTMQLALGGHLHRWVDYRIVAPTDVFVVAGLRYDADNFWVIEFDPASQTYEILDI
DKVHWQTPFSDTATE
>G0QKA7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ichthyophthirius multifiliis (strain G5)|TrEMBL
PQYFFKKIEYIHTTAEYVAKIGSSFEDMVSSKEQNNPNFCFLKKDDPYRPYYEHKIAEFA
RNMSQQQQNGNNNNIINDQQHQQQQQQQQQQQQQIQENIFQQNKEQILQREVQAIQYEQM
QLEADIQNQIEQSIFSIDIAKDINSLDLDIIKHTAQFVAKNGKKFLVSLSEREKQNPQFD
FLKPTNNLFNFFMNFVNAYQKCMQIDDNQMDNLVKFAKNKQNIYNRSLKVFEYLKMKRNQ
EKNQFEQDEKERLLLQQIDWQDFIIVETIDFHDNFIYTAQQMHQNQLEQQLEPQIVLEIP
PDQQNIPQQEFKEPKSIPKKTTKKKTLYLHRKLFYNNNRKKIQRQKQTIKGKKPKQK
>A0A4Y7ZQ42|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Psychromonas sp. RZ5|TrEMBL
MNDVVHTKASIAADVKGDLKLLQITDTHLFADREKNLLGIKTVASYDAVVKHAEKYSGKC
AAILSTGDLSQDHSAQSYLHFSERIKSLNMPCYWLPGNHDMQSVMLPSLLSEGLAQTKQI
VSDHWQVILLDSQLEGVPHGHLSDDQLVFLEEKLQEFPDKYTLVAVHHHILPVGAAWLDQ
HILKNNAQFIALISQFKNVKAVLSGHVHQAFDVTKQGVRYLTSPSTCVQFKPRNNDFAVD
NKEPGYRYLVLKQSGEIETQVERIDAGEFITDENATGY
>A0A511QM19|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio superstes NBRC 103154|TrEMBL
MERQIVEPQIVATEETVQLVQITDTHLFADDEGCLLSVNTGQSFIATVNDIVERNVEFDA
IVATGDISQDHSAASYTRFADGIKPLEKQCYWLPGNHDQKSNMVTVLPSPQIQEVGHVLA
GEYWQIIMLDSQVEGLPHGYLETDQLELLHNKLAEFPERHTLVLLHHNALPIGSAWLDQH
KLQRAHQFWEVLGRHQNVRAVLGGHVHQDFEKEHNGVRVLATPSTCIQFKANNDEFALDT
LSPGWRHLQLHKDGQLESQVHRLEEGCFIPDFEAEGY
>A0A5E7AIQ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSAAPSSSVLLVQLSDSHLFAEADGTLLGMNTRDSLEKVVERVLAEQSDIDVVIASGDI
SQDGSVESYEAFRRLSGQIAAPARWFAGNHDELPQMEQVAQGAGLLEPVLDIGQWRVTLL
DSAVPGSVPGFLAESQLQLLAQSLSEAPDRHHLVCLHHHPVAIGCEWMAPIGLRNAEAFF
AVVDRFPQVRAVLWGHVHQEFDQMRQGVRLLASPSTCIQFAPGSEDFKLDTLAPGYRWLR
LHDDGQLETGVSRVVGMVFEADYGGTGY
>A0A4R6V8H6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mesocricetibacter intestinalis|TrEMBL
MAASTYIFDSDRDKVRLIQVTDSHLFKDEKGELLGINTLASFEQVLSEILDSGYEYDLVL
ATGDLVQDSSDEGYHRFCRSIRKLEKTVFWIPGNHDFQPKMFDILNRSNGNIEPKKHILA
GKHWQILMLDSQVFGVPHGQLGQYQIDWLEAKLRDYPDRYALIVLHHHVISTNSAWLDQH
NLRNMQEFANTLSPFRHVKGILCGHIHQQVDDQWKGYQIMATPSTCIQFKPDSNAFSLDL
LQPGWREIELHNEGTITTRVRRIQKASFLPNTHEEGY
>A0A8D2GPG2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Urocitellus parryii|TrEMBL
MARPRGLGRIPELQLAAFPAAAAEDXAFLPEPPAPPAPRRPRSPPSSPVFFASPSPTFXR
RLRLFRSFQDLGRQPWAGFEGENGPTPSPGRSPLDSQASPGLVLHAGAATSQRRESFLYR
SDSDYDMSPKTMSXNSSVTSEAHLYLLPPPFQVLASLRSVRSNFSLLTNVPIPSNKRSPL
GGPTPVCKATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELT
HLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKERGPQEAPXQRPSQQPLPLGPQFQP
MSQITGVKKLMHSRSPNTSVPRFGVKTDQEDLLAQELENLSKWGLNIFCVSDYAGGRSLS
CIMYTIFQERDLLKKFHIPVDTMKVTSSGVLLLDNYADRIQVLRNMVHCADLSNPTKPLE
LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
VHPDAQEILDTLEDNRDWYYSEGGAEAPEGGVPTLLYYTYCTIVPGKGALCNFMGSCVII
GARAGQSLPPAPSPGAGVTGKRPPTQSGWV
>A0A5H6AD59|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Offa|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A7W4AMI7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. SR44-4|TrEMBL
MLKDAVHYSVAENEPVRLVQVTDPHLFADPEGQLLGVNTAQSLQAVLNTFIATQYPANIL
LATGDISQDYSPESYQHFVQKIEMLDLPCHYLPGNHDDPRLMSLRMQGEKVFGQQRIIIG
NWLILMLDSTVRGKPGGYMGEQQFALIEASIKATPDKHVLLVMHHNPILMQCAWLDQHCM
MNGEDFLQRTSRYPQVKGVLWGHVHQQVDNIHRGPHGPIPLMATPSTCIQFKPLSSYFAL
DHRQPGYRLLELAGDGSIRTNVYRVPGNRFAPDNEASGY
>A0A6C8M0W7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Lubbock|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A5M8NU18|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Ordinivivax streblomastigis|TrEMBL
MIKIFRFLVSCLLSGILFTVYANEPAVRFAVISDTHFGNPVALTKVPQSLKVLLSKKPVV
DAIFVVGDLTNNGTREQYEQLMSVFADKSLIPEGVTVYLMMGNNHDKTNEAGREYFLEIT
GQPLRYYADIHGFPFIAFSEGGGDLNEFNKDAKQWLEKTMADAAKKYPGKPIFSFSHVSP
LNTCYGTLSSEGWGTGLFLPVYNQYPQAVVFGGHSHFPIGDPRSINQQTFTSINDGGLYY
SEVAFGEITMGIHPENNNHVAEGLIVNVFSNNDIEIERWDTYRDEEILPRWKMNAPYDGS
QFRYKGYNGLPVPAFASGAKLTGKQDGNRYEVTFPQATDNDVVFRYFIEFLENDKVVYSY
SKFSQFYLNSEMPKVLSQTLSGLPYGKTLTPRIVAADSYNNRSEPLTGEVFTLPRYAPDR
KTKLPVACSDMTTGSYLNAFSVEAKLKVTTEQQFISPFKQTENGRPGFNKAADGRITFSV
PIGKRNKTVVCPVILNAGQEYHLVATYEKAAGKLQLYVNGALVGEETVVATDFPVFPNDK
FSLPADISVYNNALSNDEIWLLYRKSKVRDTR
>A0A4R2N050|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bisgaardia hudsonensis|TrEMBL
MVNTYKYQSSDNIIRLVQVTDPHLFQDEMSELLGINTQASFSQVLQEIQESTFDYDFVLA
TGDLVQDSSEEGYLRFCQGINKLQKKVFWIPGNHDFQPKMFEILNENQGNISPLKHLLLG
DFWQVIMLDSQVFGVSYGELSQHQLDFLHSKLQAYPERYALIVLHHHIVLTNSAWLDQHN
LRNIQEFKQIVTKFPNVKGILCGHIHQAVDSEWFGIKMMATPSTCIQFKADSNNFALDAV
QPGWREIALYDNGFIETSVKRVQKAVFLPNMLSDGY
>D4HVA5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia amylovora (strain CFBP1430)|TrEMBL
MDSLLKLPVASGSRVRILQITDTHLFAGKDETLLGVNTWASFDAVLEAVAAEQRHYDLIV
ATGDLAQDHSVEAYQHFAEGIARLSAPCVWLPGNHDYQPTMFSTLGASSIADQKQVLIGD
HWQAMLLDSQVFGVPHGELSEYQLEWLDRAMAAEPQRHTLILLHHHPLPSGCSWLDQHSL
RNPHMLDAVLQRYPRAKTLLCGHIHQELDLNWHGRRVLATPSTCVQFKPHCTNFTIDAEA
PGWRWLDLAADGHLETEVKRLNTRMFNPDLDSEGY
>B4NMM0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila willistoni|TrEMBL
MGCSPSTLPTSSSSTTAAAPGAPPLSIDATEKDGSRLFCIKLRRSRLRRCSCGAVTLTQN
GDGNGSTAGSAICGDNLCNQVLLNPLQTKNEADYEKLSTGKKDSIVTVAALGNFTHSVVR
RATGSTGTSGTSSSGGGNSRPGGGHRKSSLALVLTPEDEPMDVYQRNLMDLKYPTVLPPN
PQLKALLVFHKADSICEVVTSACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDA
RSTKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLA
MCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLNMR
LDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMHVRVVPVACIGSAP
THLIFNFDIPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSL
PLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIG
ALLTGPSVYSSRRSSNDSIIRTGTSTRTASIVPAKMKANPIIMELLEESLSWDFDIFKLE
EITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADVMQ
ATGAFITQLSNRDMMVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNNPLAILYNDLTV
LESHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVF
GGEEPREMSQSEEETSILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYFMQTDEEKQR
HLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDE
QGVNTLADIMAKQPPVGNKLTNSKXHTAFRRLFSGLLKPLPAQAPATSTIGETTEMEDVL
>A0A7Z3CIU4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. SK|TrEMBL
MPQPDQSRPVHVVQLTDAHLFADPAGSMLGLNTRDSLRHVVAQVRREQTLVDLLLCTGDL
SQDASVASYEAFRELTTPFAVPTRWLPGNHDEARLMAQVAPELVQAVTDIGAWRIVMLNT
AVPGATHGWLQDDQLALLTAALASAGDRHCLVCFHHQPVDIGCAWIAPIGLRNAQALFAI
VDAYPQVRALLWGHVHQPWDEMRAGRRLLATPSTCIQFAAGSEDFKVSEEQPGYRWLRLH
ADGRLETGVERALDFEVKLDFDSPGY
>A0A1Q9P8R1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Thorarchaeota archaeon (strain AB_25)|TrEMBL
MVKILAVADVHSPRYLEEFVKALAHHEQPDVFLLAGDMINRGNAEEYTTVLNTIEKVLGT
DFPIIGCFGNEEYSEVRKEIISTVGDRMIFLDEKSFILESNDLKVGIVGTQGSLDKATSW
QRRNIPSVKGVFERRAKRAASLLKKMKDKVDHRILLMHYSPCLETCEGEDTKAFSWLGSR
KFYRVVVEHQPDLVIHGHVHNSNRHEVTIGSSLIRNVALPAVGFITELNVWDATRT
>A0A6F9ZGN6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacteroidaceae bacterium|TrEMBL
MPPYCFFLNFASMKIWKLTLIHILATITLQSCEIIDYHPYSADFDGARNINADNIARIEA
AMAGRDSLCFAVISDTQRWYDETASAVRSINARNDIDFVIHCGDLTDFGATREFEWMRDE
LQKLCPPYVCLIGNHDCLANGTHVFNAMYGHPNFSFTAGDTHFACFDTNALEYDYSTPVP
DFSFLKRDSESLPPNVRRTVVAMHAAPFTDQFNNNVAEHFQNELKTYPGLQFCLSGHRHS
TTVFQPFDDGVTYYECASAKQREYLVFTLTQKGGVRYEVVVY
>C9P1I6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio metschnikovii CIP 69.14|TrEMBL
MNVSPSLDPSDNIKLVQITDTHLFAADDGCLLSVNTADSFHAIVQAIIEQKVAFDALLAT
GDISQDHSAESYQRFASEISALQKACFWLPGNHDYKPNMGSVMPSSQLHAPEHVLLGKHW
QMILLDSQVVGVPHGRLSDYQLNLLDEKLAQHPDRYALILLHHHPLLVGSAWLDQHTLKD
SDAFWSVIQRHQNARAVLCGHVHQDMDRTFAGVKVMASPSTCVQFKPNSDDFALDQCSPG
WRELELHADGQVTTQVKRLARGAFVPDFTSNGY
>H6WS60|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rattus norvegicus|TrEMBL
MPEANYLLSLSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQ
KDREKKKKQQLMTQISGVKKLMHSSSLNNTSISR
>A0A6M1YLP5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Anoxychlamydiales bacterium|TrEMBL
MQIFAISDPHLSLSTPDKNMQDFGDTWKDYQEKIKNNWEKNITDNDLVLIPGDISWAIKL
KDALIDLEWIHDLPGKKVIIRGNHDYWWPSVTKLKEALPPSISFIQNNSLNFGDISIAGS
RLWDSTEYNFKDYINFVFNPKERKDLQGNIHKDLSERIFIREIERLKLSLEGIDKNAKTK
IVMTHYPPISADLKDSKVSKLLEKYNIDICIFGHLHNLKKEKKMFGEKNNIKYILTSADY
INFSPVKIL
>A0A2N7C5N7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio lentus|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIKPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQIVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPDRNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHSNVKAVLCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTEVRRLPHGQFLPDFAAGGY
>A0A158P0G0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Atta cephalotes|TrEMBL
MGCNISILKCMKDKVEQEKNISSETSSSIVTSELEQHKTDAFEIVAEKDEKIPFEDSKHD
ENGDYLTVSYFPKGPQDLSNYLLTTNVPSIVKILLVFSKDDQQMDILANTARRLGWSVSV
AKDAEKALELFQNRAHELVIIDHRTHHAAEGDAICRAIRSSPVYHNSVIIALVKKSYFML
DEKDHIVALNLLETGFNRALMECSHEGILINELVGIYTSSLLPRTQLAAAHALYLALDRC
RDMVHVTNDKNIVQFLNKVSEKLLGYQVEEMMGRNLSEIVYYENYSVMEQQLKKGREFEG
NMNCKRKNNQMITINCRIIPFCITLKKPSHYIYVYDTTYLSENSAPISPISSPLHPPIKT
SITNARKSSDVRSGSLSEDKGRRRSSLQKLHTLQLEAPITKVIMLLSIAVTDTINPETAA
QIDKAIDILKTTELYIPHLKEDRAICCDPVATDLVGALLASPRTAWESRRSSSDSAKLST
IKAITSPVNSRVQVKNFRGPQEIMEILDRSLDWDFDIFKLEVLTEKRPLVFLGLTIMNLY
QVSTILQCDERILQNWLAIIEHNYNAENSYHNSTHAADVLQATARFMQSKRLKEILEPLD
EVASLIAAAAHDIDHPGRSSQFLCNANNRLAILYNDLSVLESHHAALTFKLSLSDDSVNI
FKNMDRDAYKLLRQNVIDMILATEMTKHFEHLAKFMNVCSARIGDGQETYSDSVDMSVVL
QPENIMLVKRMMIKCADVSNPTRPLKCCVEWARRIAEEYFNQTDEEKKLKMPVVMPMFDR
MTCSIPKSQIGFVDYIINDMIEAWDVFIDMPEIVGYMRQNYEKWKEYNEQGISTLQDLEK
LQQLPEMQILS
>A0A6I4PYV1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gilliamella sp. Pas-s95|TrEMBL
MLKLPIRNKNYGKILHITDTHLFSEDDGSLLGVNSNASFRSVINEIGSSNKTFDLIVATG
DFVQDGSKKAYARFAEQINKFNTPCVWLAGNHDNYESMQDVFADYQLADNKIVQLGDNLL
IVLLNSQVIGQAYGFLPKSELEFLHNALTEHSDRNALVFLHHHPINSGCHWLDHHILKNS
DQLEQIIQKHSNVKGIGWGHIHQKQDYVWHHCHAFSTPSTCFQFKPECYDFQVSTEDAPG
WREITLNTDGSIESEVYRLADNQFLPDVSQNGY
>A0A3P4MCA2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gulo gulo|TrEMBL
MKPRSRSTSSLRTTEAACFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYR
SDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKR
SPMCNQPSINKATITDYGLQTTLMKSFSKLWRFF
>A0A645B4F0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MYSRTYYPTVVLSDIHLGSPHAKTEEVTAFLKSVNCDKLILNGDIIDGWHLKKSGLHRWK
AKHTEFFKVIMKMMENFGTEVIYVRGNHDDFLDALAPLNFYNVKIVKDCIYESKGKRYYI
THGDIFDTVTTQMKWLAMLGDTGYSFLLWVNKVYNAYRMKQGKPYYSLSQKIKHKVKSAV
SYVSDFEKELVNLAKSKKCNGVICGHIHHPENCYYDGIHYLNSGDWVETLSALTEDENGN
WEVKYFDRADYRVTAFQEELAVIDKLITIAS
>A0A644YG70|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKGIQAGKAGDSLVIRALSPLPAVEITNKAAQQDVIIAIENINPDFYAARIGQGFSPARI
SVNTLEFALTINAGDTADIVPAMPSDTEDDNYVILGDSRDGYETFDTILSQVNAKNPVFV
IDNGDLVYSGKPNQYRIFDEMVSGISSTLCTTLGNHDVRGSGRATYVKLYGPEYYSFDYG
ENHFIFLDSSRGFTQEQAIPDEQYAWFERDLQKAQGKRIYVVSHVPPTDPRAGIEPNEIL
AYTDKVKKEGGYIEQKLEAYADNENLDHGFISKKEAEKFETLLAKYHVTTAYFSHIHSYF
DYEKSGVRYVISGGAGAELMTRNSYYHYLIAKAGAKDTLTMVQLPSPANLILQRYGATIT
LFAQAAYRENRAAVLLLKAGLYLLAALVLILLYLKFETRLAAFWVLMRDTGRYMGKRYKE
LFKLKQN
>A0A2P5GNG1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Superficieibacter electus|TrEMBL
MESLLTLPLAGGAKVKILQITDTHLFAEKHETLLGVNTWESYQAVLTAIHAQQRECDLIV
ATGDLAQDQSAAAYQHFAEGIAGFAAPCVWLPGNHDFQPAMYSALQEAGISPAKRVWVGD
HWQILLLDSQVFGVPHGELSEFQLEWLERKLAESTDRHTLLLLHHHPLPAGCGWLDQHSL
RNAQELDNVLTRFPRVKHMLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCASFTLDTIA
PGWRWLELHDDGTVVTQVCRLQSTQFSPDTASEGY
>A0A7Y8CI96|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas gingeri|TrEMBL
MSSVATQSTTTDSVLLVQLSDSHLFAEADGTLLGMNTRESLQRVIDCVLAEQPRVDLVLA
SGDLSQDGTLESYQCFRQMSGRIPAPARWFPGNHDELREMAEAASHSDLLEAVVDIGNWR
VTLLDSAVPGSVPGYLQDEQLQRLVQSLSEAPQRHHLICFHHHPVSIDCAWMEPIGLRNP
EALFAVLDRFPQVRALLWGHIHQEFDQQRNDVRLLASPSTCVQFAPGSEDFKVDDKAPGY
RWLRLHPDGRLDTGVSRVQGFDFNVDYGGTGY
>A0A7R9N9Q3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Methanoperedenaceae archaeon GB37|TrEMBL
MRILHTADLHLGRTGKDRDIWHQWEKIIEIALKENIHILLIAGDVFDNGQAEAVLKKKFV
ISLNKLANQGIQIFIIPGNHDLRQGNALTDLELPGVNVFYKYTVVNLDKIALHFFPFKPE
LSGQDLVGLKQDSGAECQIGVCHASYITLPEVFSDLGDSQAIHCPLSPEDIRDLNLDYLA
LGHYHNPKQWQVGKTQCVYPGSIEPLSFKEIGPRQVFIIQYDHGLRVYPIEIGYQRPYLC
QDIQIPKEDIHALWPKIEELAQDFGPCFLRLTIKGVADKLLFQAFQLKAEAFLKERAIEV
SWQDETVDLGWIEENRLAKQFKEAVHHRIRQSPEKEFWWQVLYRGISLLKHCENVDKKNK
V
>A0A1X1PDH3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Burkholderia puraquae|TrEMBL
MFAWHRNKITNANDGKKPGDVPTTVMHVSDLHFGYRFDNILWKDVVRRAVSIRPDLIIVT
GDVVNTPWRLAVKRAGERLIELRDRLRLETGKHHLEIFVVPGNHDTRISGLFPIQWLLPT
TVLLALAAVATQWWFPFPNAPLLAKIVESALWGVAAIGMCLRLVTTSKLGRGEREQLFIS
HARVLDGFNVGVIPFDSASEGIRWAAGKVKRGALGAFRDVAGRFEAADESLGVFWIAAVH
HHPVPLPYDAGNETMMIMTNAGKFLHELASYGVPLVLHGHKHHQHFSKLSFQTPYSTQSQ
IAILSASTPTESNGAGAFRHGFNVIHVNEEHQATVSVYSAQPTGETFALKKNFCIAESSE
MARRRFESYLGRKGVVCQRAVFTTVIDDFGGAVIKRRFYGLESMHAPLSQVPGTFELSCH
EGHVGEVTVEPLSEVVPHMTVREGERSVSKVVCSIDFEGSLLAPRMPVDLELEVQGSNLF
ALDMRQFEELYNDPNATVEEMIWTVPEGLAMRELQLHLKFLSRGVHPSQIRLSRAIDKGQ
PWRPCDEHISFVQGDSSATVTILHPQPNGRYRLTWRPPEPPPEASEILRGRSRAARERLL
YATDEQKARIREWLPFLADFAGSQVFDTQQNAVVHAAVFSYEGMEKKLQIVASTYAGEDL
RRRWSFGYGRGLVGATFKLNQIAGFDKTSCDDYGFTHYLRGDGMVASCASDVLEGGAYAF
PLRMEDGDGRQSNEPFGVLLVSVDGWGGQLAKLEAPAGEPENPLLGQLSSFASQEILKLL
ESAIIPDATGEHPWIKPRHRTSSRRRARRPRKASSNFDRIFTKR
>A0A7R9R5Q1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Methanoperedenaceae archaeon GB50|TrEMBL
MKKYLFNKFISCIVILTLIVSVGIKLYSVFTFPEIEDWNYKQIKKIDETHNSYSFAVFGD
NRNSITTFNNLIHKLNKDSIIFAIDVGDLVEDGKKEKFRFFINQIKKVNKPFLTVIGNHE
LRENGRANYYQMFGRFYYSFTVGKSYFIILDDANEKRLDLWQLDWLKKELEKSQSYKYRF
VFMHVPLYDPRKGGDKKGHSLKDVTFARYLNKLFDKYHVSMLFCSHIHGYYKGYWQNTPF
IITGGAGAKLAGTDPSHYFYHYIKVNISEQGVQYEVVRLNTPDFELIDRLLHDTGMFIYA
FIAIHFDIIIIIGCIYILILLYFKQDKIKIMYHA
>A0A6B0TCS9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter koseri|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAGQHEYDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVFIGD
QWQILLLDSQVFGVPHGELSDFQLEWLERKLADAPERHTLLLLHHHPLPSGCSWLDQHSL
RNAAELDSVLANYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIG
PGWRTLELYAEGSLETQVHRLPGTQFRPDTASEGY
>A0A7U6R2A1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas hydrophila|TrEMBL
MRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHPFDLILATGDLSQDHSPESY
QRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQVILLDTQVRGKP
HGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNADDLFAVLARHPQ
QKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGWRYLTLYPDGRIA
SQVWRLPVGQFVPDPNATGY
>A0A1H1CDN6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas grimontii|TrEMBL
MPSVSTLNPDAALLVQLSDSHLFAEADGTLLGMNTRESLQRVIELVRQQQPHIDLVMATG
DLSQDGTLESYQAFRDLTQQIKAPARWIPGNHDEPRIMLHAAAHSDLLEPVVDLGNWRIT
LLDSAVPGSVPGYLQDSQLQLLAQALSEAPNRHHLVCFHHHPVPIGCAWMEPIGLRNPDA
LFAVLDRFPQVKAVLWGHVHQEIDRERNGVRLLASPSTCIQFTPGSEDFQVSEHAPGYRW
LRLHADGRLETGVERVKGFAFTVDYGSNGY
>A0A1I0UBA4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas otitidis|TrEMBL
MSSANRHAAAPSVLLVQLSDSHLFAEEEGRLLGMNTHDSLSRVIDQVLEEQPAIDLVLAT
GDLSQDGSPESYVHFRDLCARIPAPCRWFPGNHDEVQVMEQVCRDSDLLQPVIDFPAWRV
VLLDSTIGGAVPGHFPPAQLALLEQALSEAGDRHVLVSFHHHPVPIGCRWMDPIGIRNPD
ALFEVLARFSNVRGVLWGHVHQEFDQLRDGVRLLASPSTCVQFAPGSEEFQVGGEAPGYR
WLRLHGDGRLETGVSRVTGIDFEVDYSVKGY
>A0A379CM65|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Plesiomonas shigelloides|TrEMBL
MESLFQPPVATERVRLLQITDTHLFADEEGALLGINTLQSYHAVLDAIVAEQQIAEQQPV
DLIVATGDLAQDHSLEAYDRFADGISRLDSPCVWLPGNHDFQPAMVDGLRGKGIQPSKQV
LLGDHWQLILLDSQVLGVPHGELSDYQLNWLAARLDAHPERHAAILLHHHPLPSGCTWLD
QHSLRNSHVLDEVLSSRPQAKVVLCGHIHQEMDLNWNGRRLLATPSTCIQFKAHCTNFTL
DQLTPGWRYLDLLPDGRVETQVHRLTDQRFSPDMESEGY
>A0A6S4TU68|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas caviae|TrEMBL
MRLLQITDTHLFASAEGRLLAVPTAQSLAAVLERVQANEHPFDLILATGDLSQDHSPESY
QRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGDHWQVILLDTQVRGKP
HGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNADDLFAVLARHPQ
QKTILFGHVHQEFDEVHHGVRLIASPSTCIQFKPLSDGFALDESGPGWRYLTLHPDGRVA
SQVWRLPLGQFVPDPNATGY
>A0A0M3HEG7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella aerogenes|TrEMBL
MESLLNLPLAGETRVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLHDAGISPAKRVLLGD
HWQILLLDSQVFGVPHGELSDFQLEWLEHQLNAEPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDHILSNYPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGVLTTEVCRLSGAEFHPDIASEGY
>A0A661HA58|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MHQSPHNTHFIEASPDVVRVVQLTDTHLCQAKGGTLLGLDTDQSLQAVIELVQDERPAID
LLLGTGDLADDGAREAYDRLQDYFEEIPCDSFWLPGNHDDRGKMEAVANSATRLCKEIRV
SRWQILMLDSQIPAEVGGELGQAELALLEQMLLSARDEGLHTLVCLHHQPVAIGCAWLDE
QMVADADAFFDVLDRYPGVRGVLWGHVHQQIDRQRNGVSLMASPSTCVQFAPGSVKFKAD
KMLPGYRWLDLHGDGRIETAVSRLSDAHFIVEPDSGGYL
>A0A5W5H0T1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Java|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A5J0V9P8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Agbeni|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDVDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A1W4U9K2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila ficusphila|TrEMBL
MGCSPSTLPAPSASASAAGGQSAERGSLPLDASEKDESRLFCIKLRRSRLRRCSCGGVTL
QPPSDGNGSTTGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHSVVRRA
TGSTGTSGTSSSGGGNSRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLK
ALLVFHKSDSICEAVTAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSTK
NLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSV
ELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEI
ISKQLEDIFVSDLSTISEQCKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLI
FNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEA
PITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLT
VTKGPSVYSSRRSSNDSIIRTGSSTRTASIVPAKMKSNPIIMELLDESLSWDFDIFKLEE
ITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQA
TGAFITQLTNKDMMMMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVL
ENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFG
GEEPRDHNSQTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQR
HLPIVMPMFDRATCSIPKSQIGFIEYIIQDMIHAWESFIDMPQLITYMQINYSQWKKYDE
QGVNTLAEIMAKQPPVGKMANSK
>A0A5P2MI25|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter werkmanii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEFDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSSLQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVCRLQGNRFHPDTASEGY
>A0A0J4X2Y2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella quasipneumoniae|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVFLGD
HWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A6P3UIL6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bombus terrestris|TrEMBL
MGCKTSMLECIEDTGEAEKRKHSDMVNQGSLLGKTEYDVLRRRSSFEDIAVDDDENADCS
ALKGPQNIEAHPLTNSVPSLIKILLVFPKDDQQMDVLATTSRRLGWSVSVAKDAEKAVEF
FQNRGHELVIIDHRGQRAAEADTICRAIRSSPAYHNSIIIALVKKSFLMHGEKDKIVTLD
LLETGFSRALMECSHERLLINELVGIYASALLPRTQLAAANALYVALDRCRDMVHVTNDK
HIVQFVNKISEKLLGYKTSEILGRSIADIVVYDNFVLMEQHISKGREFEGNMNCKRKNNQ
MITISCRVIPFSISLKKPTHYIYIYDTTYLSENIGSLSPTPSQSVYSRGNMIVSQRRTSD
MKSSEGRRRSSAHKLHSLQLDAPITKVISLLSNAITESTTPDTTAQIEKAIDILKTTELY
VPSLREDTDPVTTDLVGALLASPRKAWESRRSSVESTRVSTTKGFTTTTASRMQIKGFRG
PQEIAEILERCLEWNFDIFKLEILTEKRPLLFLGTTIMNLYRVPARLGCEEKVVQNWLTV
IEMNYQSRNSYHNSTHAADVLQATARFMQSERLQQILEPLDEVATLVAAAAHDVDHPGRS
SQFLCNSDNKLAILYNDLSVLESHHAALTFKLSLSDDNVNIFKNLERDTYKQLRQTVIDM
ILATEMTKHFEHLAKFMNVCSARMMDSPQLDDYSDTVDMSVVLQPENVVLVKRMMIKCAD
VSNPTRPLKCCVEWARRIAEEYFNQTDEEKRMQLPVLMPMFDRATCSIPKAQIGFVDFII
NDMVEAWDAFIDMPEMVGYMRQNYEKWKEYNDRGISTLPDIEKIQELPELRIYQLPS
>A0A0H3AZK4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia pseudotuberculosis serotype O:3 (strain YPIII)|TrEMBL
MALPADSHNTHNYLVGGRQKQGYHLESLFKLPMASGARVRILQITDTHLFAGEHETLLGV
NTFHSYRAVLDAIIAEQHPFDLVVATGDLAQDHSVAAYQNFAKGISRLPVPCVWLPGNHD
FQPAMVGALAEAGIAPSKQVLAGEHWQILLLDSQVFGVPYGELSDYQLEWMERCLIAYPE
HYTLILLHHHPMPSGCTWLDQHSLRNAHMLAAILTRYPRVTTLLCGHIHQDLDLDWYGKR
LLASPSTCVQFKPHCTNFTLDAVAPGWRYLDLLPDGGAGN
>Q4TH07|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Tetraodon nigroviridis|TrEMBL
GNDTDITGAGEKAESSRYSRSYTSGATLGADLRRGRSRRLSSSLQVPCWLRPRDRTRSPE
LLNNAPRPTTLPLRIPPRISITQADANRSPVPLAALQLRNGKWPLAGSHPLGSQSPGLTL
HSSLQGQRRESFLYRSDSDYDMSPKTVSRNSSLASEGHTAEDFIVTPFAQVLASLRSVRS
NFTILANVSTPTVKQLTAALALFRRSPLSVSPRATLSDQQYQQLALDTLEELDWCLDQLE
TIQTHRSVSEM
>A0A447UKU7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter koseri|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAGQHEYDLIV
ATGDLAQDQTAVAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVFIGD
QWQILLLDSQVFGVPHGELSDFQLEWLERKLADAPERHTLLLLHHHPLPSGCSWLDQHSL
RNAAELDSVLANYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIG
PGWRTLELYAEGSLETQVHRLPGTQFRPDTASEGY
>A0A6A9JZ54|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas aeruginosa|TrEMBL
MSRHSNTPATDASVLLVQLSDSHLFAEDGARLLGMDTAHSLEKVVERVAREQPRIDLILA
TGDVSQDGSLDSYTRFRRLSAPLDAPLRWFAGNHDEREPMQRATEGSDLLEQVVDVGNWR
VVLLDSSIPGAVPGYLEENQLELLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGY
RWLRLHDDGRLETGISRVDDVVFEVDYDTAGY
>A0A6B8MY75|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella oxytoca|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSTAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQILLMDSQVFGVPHGELSEFQLEWLEQKLAEVPERYTLLLLHHHPLPSGCSWLDQHSL
RNAGELDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A891HCZ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. LZH-2|TrEMBL
MLKEAISYSVADENVRIVQVTDPHLFADPEAQLLGVNTSKSLAAVLNTIRAVNYPAHLML
ATGDLSQDYSPESYRQFVSAVAPLNLPCHYLPGNHDDPRIMFLHMQGERIFGQQRILVGK
WQILMLDSTVRGKPGGHMAASQFELIEQAIAAHPDRHTLLVMHHNPILVNCAWLDQHCMD
NGTEFLKCVAQYPQVKALLWGHVHQQLDSLYDGPHGALQLMATPSTCIQFKPQSPYFALD
GLQPGYRLLELKADGSISTNVYRVPGNLFSPDKDSSGY
>Q65RW0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mannheimia succiniciproducens (strain MBEL55E)|TrEMBL
MISNTYIYEADSDVIRFVQITDPHLFKDEQGELLGVNTQQSLTQVLTELKENQFNYDFVL
ATGDIVQDSSEEAYLRFCKSVQQLDKMVFWIPGNHDFQPKMFDILVQEHGNLSPKKHLLL
GDKWQILMLDSQVFGVPHGQLGQYQLEWLDSKLKDNPDRYSLVVLHHHILPTHSSWLDQH
NLRNAHELAQVLAQYDNVRGILYGHIHQAMDGTWKDYQIMATPSTCIQFKPDSNVFALDT
LQPGWREVELHSDGSIITRVNRIQKASFLPNMQEDGY
>A0A0F7LQS2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus thracensis|TrEMBL
MESQFKLPVVEGTTAKILQITDTHLFAGREETLLGVNTYRSYHAVLDAILKQNADIDLIV
ATGDLAQDQSLEAYWHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILIGE
YWQLLMLDSQVSGVPHGELSEYQLEWMKKCLDMYPERYTVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQGYTRVKAMLCGHIHQEMDLDWNGIHMMATPSTSVQFKPHCTNFTLDTVA
PGWRYLELSISDRGEFSLTTQVHRLESNEFCPDLDSDGY
>A0A3G2NBR2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. LTJR-52|TrEMBL
MALATSPDFLAAPLVVQLTDSHLFSSPEGRLLGLDTRYSLEQVVERVRAEQPTIDLILAS
GDLAQESTPEAYQSFKELTACLDAPARWLPGNHDKVKVMQTFCAGTDLMDPVLDMGQWRL
IMLDSTINGAVPGRFDQEQLELLEKALSEAPDRHVLVSFHHHPVQVGCQWMEPLGILNPE
ALFEVLDRYSQVRVILWGHIHQEFDQIRNGVRLLASPSTGLQFEPNSVDFKVGMQAPGYR
WLRLLPDGAIETGISRVEGVDFNVDFQGSGY
>A0A811TFS4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Argoarchaeum ethanivorans|TrEMBL
MTVKIVHLSDIHTANPHFLPEMALKVVERINEINPEILIITGDLTESGYPFEFECAKSYI
EKIDCASKVIIPGNHDVRHVGDLCFEEIFGSRSKVRRYKGITIVGIDSTQPDIDDGHIGR
DKYEWIEKCFDTDDFKIFALHHHLMPVPFTGRERNIPVDAGDVLELLVRCKVDLVLSGHK
HVPWVWNLNGMTILNAGTACTNRMKWSIPQSFNLIELDKEMLKIYKIYSKGGHELILEKP
HNFVVQG
>F4N2W9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia enterocolitica W22703|TrEMBL
MESLFKLPMASGARVRVLQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGISRLPAPCVWLPGNHDFQPAMVDALANAGIAPSKHVLMGD
NWQILLLDSQVFGVPYGELSEYQLEWMERCLMAHPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLNWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGRLETEVRRLASDEFCPDMDSDGY
>A0A803Y7Q1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Meleagris gallopavo|TrEMBL
MTAKDSSRELATPESEIYIRTFKEQMHLELELPKLPGNRPTSPKISPRSSPRNSPCFFRK
LLVNKSIRQRRRFTVAHTCFDVENGPSPGRSPLDPQAGSSSGLVLHTTFPGHSQRRESFL
YRSDSDYDLSPKTMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTANN
SPGCPEPHPAWP
>A0A836TY06|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Thiotrichaceae bacterium|TrEMBL
MFDSKEKNEKGTVVLIKPGGSIKIIQITDTHIIDDDAPLFSGFDTSVSLLQVIDNIRENE
SDADLILLTGDLIHEATKTSYHKLSEHLSTLSIPVFCLPGNHDDPEILNEIMTMNGYGLG
KVIKAGQWLIILLDTCVKGEHRGELSNSELEFLETTLASHANTHCLIALHHHPVPINSPW
MDAMSLTNTKELLSIIDKFDHVRALVWGHIHQEFELLRNNVRLLGTPSTCLQFKPESDVY
AVDDKPPAYRKLELLEDGNIKTEVVYVLE
>A0A6C8GJ40|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Adelaide str. A4-669|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>V0AM19|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pneumoniae 909957|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A7Y1BIL0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. WS 5011|TrEMBL
MPGAPIQTTAVDRSVLLVQLSDSHLFADGAGKLLGMDTQDSLQRVIERVLQEQPQIDLVL
ASGDLSQDGSAESYQRFREMTAAIPAPARWFPGNHDEVPAMQAACVGSDLLEPVIDLGNW
RVTLLDSSIPGAVPGYLSEQQLALLERALSEEPDRHHLICLHHHPVSIGCKWMEPIGLRN
PDALFAVLERFSQVRAVLWGHIHQELDQQRGPIRLLASPSTCVQFAPGSEEFQVDKTAPG
YRWLRLFDDGRLETGVSRVTGIKFEIDYTIKGY
>A0A1Z3HVI8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Halomicronema hongdechloris C2206|TrEMBL
MVKFLHVADVHLGFDRYDSRERTKDFFRAFQDVLQRYAIDEQVDFVLIAGDLFEHRTLQP
AILNQAQLCLQDLKAANIPVFAIEGNHDNRPYGIVTSWLKYLSEWRLLTLLEPGNVAAGE
SFYCPWDEDRRRGGYIDLACGVRILGSNWYGAAAPRAIEQIADAMAELPPGPEHTVLMFH
HGLAGQIARYAGALRYDDLLPLRQAGVDYLALGHIHKHYSVDGWVHNPGSLEANNVEEAQ
YERGAYLVELNGQGVQARLQRDYYQRPIARLRLLARGHESLRELEAAALSLLEEAIELGQ
VDPVQAPLLEFRIEGQVGFDRLEFDTRALQQALQQRSNAIICLLKYEVETVGYASPLAEE
ANRRQIEYDIFTDVLAGHRDYKKRAPELAHGLMDLKERQLQGHAEEALYAFVETLLEPGS
QASSTTPAVTEEK
>A0A5S9NYR3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Starkeya sp. HF14-78462|TrEMBL
MFVLAHLTDAHLGPLPRARFAELAGKRALGVLNWRRGRQHRFNIATIDLLVADIKAQAPN
HIAVTGDLVNVGLAAEYLTGLNFLKSLGGGADVTVVPGNHDAYVRSTAHHSLLNWGDYMR
GDGVNGDVTAESAFPFVRRREGVALVGVSTAIPTRPFMATGKVGRAQRERLAHVLDGLAE
EGLFRVVMIHHPPCGVRAGHKRLIDEEAVREVLARHGAELVICGHDHVQMVEMLPGPHSA
LIPVVEAPSFAAGPDDRHWPGGYHLYRIERVPGAPFPWRCTMEARGFQRGDPTVATRSVR
VLTEPVSAG
>A0A090S894|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio variabilis|TrEMBL
MLQLTDTHLFAPHDGCLLSVNTQDSFHAVVAEVIQQGTQFEALLATGDISQDHTEASYQK
FVAGIEPLGLPCYWLPGNHDYKPCMNSVVSTPLIQDVTHALLGAHWQVLLLDSQVVGVPH
GRLSDSQLDFLERKLTEHANRHTLVLLHHHPLLVNSAWLDQHSLKDAHEFWQVVDKHDNV
RAVLCGHIHQEMDVIREGVRVLATPSTCVQFKPNSNEFALDTRAPGWRELELCADGTVNT
EVKRLPHGSFRPDFNAEGY
>A0A7J5XEB5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dissostichus mawsoni|TrEMBL
MECTALSREGAGLAKPPKHLWRQPRTHIRIKQRFHSDTERYLCRNRTLEKLRPGLKKPRM
SWPSPMRRNMSLPTNCVYLAPSVQDRYFKVRNGNICGSPCAVNRPIDIVQKRRRFDVDNG
LSVGRSPLDSQTSPSSGLVLQANFPHSQRRESFLYRSDSDFDLSPKNMSRNSSTASDLHG
EDMIVTPFAQVLASLRTVRTNFAVLTHLQDRVTNKRSTSSQQPSMCKPCLTGQCYHPCLE
PCQKLAVETMEELDWCLDQLETLQTRHSVGEMASNKRMLNRELTQLSETSRSGNQVSEFI
SNTFLGEFAC
>A0A5F1EMJ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. E4702|TrEMBL
MESLLTLPLAGESRVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADSRFQPDTASEGY
>A0A5J4QZY2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MVIKFIMRKVYLLSLILVFFCSFQVMAQENIRIVHGPYLQNMDTDEVTLVWVTNKSAISW
VELAPDDGTHFYLKERPKVFASKNGVKLESRIHTVKLRGLIPATKYRYRIFSQEVIGREG
HEITYGKIASTTAYEPAAFVTLDPAKTAITFTMVNDIHGRSDALEQMLKWAEPMKNDLAF
FNGDMVSSLINEEDLFTGFMDVGVRAFAKNIPMYYARGNHETRGPFANSFQDYFSPLSPE
LYYLIRQGPVCFVLLDCGEDKPDTDIEYSSITDYDDYRTLEAEWLRNALKNREFIDAPFK
VVICHMPPMNDWHGEAEILNKFVPLLNDAKVDIMLCGHLHRHIKLRANEQVKFPVLINSN
NAIVKGSITNKSLTLDVVGLDGKKTDSISIQK
>A0A5J4Q448|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MLIELNNKKIFAFADTHGKHRQLDVPVDADILVCAGDVCNEGNEAQIEDFFAWFAQLPAR
HKLFVPGNHDIPFEIVP
>A0A5J4QCA5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
EFEQWVQLINKENPDIVLIAGDVIDNHPRLLYEQNMAQTFKRLKAKYGVYAVLGNHEYIS
GASKSIDFLKEAGVIVLRDSIVCIDDTFYIIGRDDRTNTARKSIEELTDTLDKSKPLIML
DHQPYHLEEVEKNNIDLQLSGHTHHGQILPISWITNRMYEKSHGYLKKGNSHIYVSSGIG
IWGGKFRIGTQSEYIVINLNIKRNP
>A0A090P487|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio ponticus|TrEMBL
MKVTSNTTVKDTIKLLQITDTHLFEAEDGSLLSVCTNDSFNAVVDAVQQEAFEFEAILAT
GDISQDHTDVSYQRFADGIKPLQKPCYWLPGNHDYKPSMSTILPSEQIVQVEHELLGKHW
QMILLDSQVEGVPHGRLSQKQLDLLETKLAEYPERHTLVLLHHHSLLVGSAWLDQHTLKD
AEQFWQVVERHSNVRAILCGHVHQDMHKVHHGASVIATPSTCVQFKPNSDDFALDTCSPG
WRELELHADGSFDTRVKRLEEGLFSPNFDSNGY
>A0A2Z3Z0K9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Corynebacterium provencense|TrEMBL
MTSDHPHHGSSTSGGHPATPGSPFPAPAVSRRRALQLFALGGAGAAGLLSATGLSPLPSA
RAQSLSPSPYPSLSGAVGSYGRSSDGGFIAGDLQVVTVTESELTVTWCTWSTERLDDGRP
TGTPTDGVLRVWPDDDPSGVREVHSPGATSFHVLTVTGLRPGTRYRFAASSGGVTPAPVL
NIYEGPLDTVTTLDAPVGPLGGTVVTTNDTHIGEDRDGIIFGDFPPPVTQARGARPYGEI
MLESVIAGAHAAGASHLFVNGDLTAEARPVEVETAKRILDTFNGRWRVTRGNHDRPHDAA
VDPVYLAAPPYRGPDQGEAGTDYRDSFGAVFEPRQQAWVEDGPGGIRVLGIDSTHRDRSG
GVINGEQFTQIEEILQEDPLRPTVVMLHHPMTRDAQWTNIGGPDFTLADADAQRLQAVFA
AAPGVRLVLGGHTHRVRRNTADPASGRRPPVYLETASAKNWPTGAMHLRVYGDRLTVNFR
HAVGPEALAWAQRTRWSTFGLQSAYSLGRHTSRNLVVEL
>S1PPM0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli KTE182|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPGRHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A235CMC1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oceanimonas baumannii|TrEMBL
MTLSTLPLGSHAASGVIELSQITDTHLFASIDGDLLGVPTWHSCRAVVNAMKEEMTGCDG
ILATGDLSQDQSALSYRHFVAMMAELAPPVFWLPGNHDEAPVMQAELDAAGISQAKHLLG
EHWQVLLLDSQAQGETCGRLSDGQLAMLDEAIDTYPHHHLLVAVHHQAVPVGCAWLDQHN
LRNADVLQSRLERHCASKVVLCGHVHQGFDEVRQGVRYLASPSTCIQFKPLSDEFALDHT
APGWRQLSLYPDGRLSTRVWRLPPDAFVPDFSARGY
>A0A5N8TCQ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salinivibrio sp. VYel4|TrEMBL
MQSCQIDNADGDCIRLLQITDTHLFASEQGSLLGINTLRSYHAVLDAISATDPTFDAIIA
TGDLSQDHSALSYRRFVDGIARWSQPCFWLPGNHDYQPEMSAVLQSNTLRSCSQVLLGEH
WQMVLLDSQVAGVPHGELSQAQLNLLDTHLSAHPERHALVLLHHHPLDAGSTWLDQHKLA
NREAFWQVMARHPQAKIVVCGHIHQALDVRYQGARVMAAPSTCIQFMPDSHDFALDNQNP
GWRWLELYADGRVETQVARVTGQHFRPDFDSSGY
>A0A8D2AW35|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sciurus vulgaris|TrEMBL
QNFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNS
SIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITG
>A0A2S2NVJ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Schizaphis graminum|TrEMBL
MGCASSSKDVFKYRHNAIEKNNTVILDRLLHDQTANTELWNTEHTVSNNDITSRSKLLNN
LPEMWDNCCRRSGSASDLSRDTVDAYSPINRSDSPLAQTPDNFNNFMFGCSKYIQDLRSN
STLKKILVVTSKDDSVWQSITITARNLEWTVNRVTSTEEALECFHKGNGVPTVAFVDCRF
QNDKAVDAHQIARSLRSIRRNAHVVLVALVRKSLVLRNEKDVTSILTSGFNKIIVETCNK
NVWIKELQQLEKEDVAMRSMLAQQDAVLAALDKTKDLVIITDLKHNIQYMNKSGSVILGY
GAEDMINKPLAVFHQLGDIDQITKKLEKNIEWDGKVSWKCKSGEHVYLHCRASPFRPFGK
DTTNYIYIQESIVDVHGFPRGSVPSIRKGSYDLKSINSDGAQSARRQSLAKLHNLPLEAP
ITKVISLICTAQENSNDQVVQILDKVVDILRVTELYSSHLKTENIKYDDPVTSDLIGALI
TQGPVHVTSTRRSSNDSATVKSQPYGLGVAKMNFMTSVTPQIKELLDMSLYWDFNVFKLE
ELTMKRPLVHLGMNLLTHFEVHKTLGCDERTLHAWLTVIEGHYHAKNTYHNSTHAADVLQ
ATAIFLEKDRIKRLLDQLDEACCLIAAITHDIDHPGKSSAFLCNSKNDLAILYNDISVLE
SHHAALTFKLTTKDERLNIFKGLEKDTYKVVRQNIIDMILATEMTKHFEHLAKFVSVCNK
PSTLDEAPVDGLTPSEVSPETIMPTSAEEVNLVKRMLIKCADVSNPTRPLKMCVEWAKRI
AEEYFNQTDEEKLNHLPVVMPMFDRASCSIPKSQIGFMDYIINDMFETWDSFIDMPEMLY
YMRSNYQYWKDLEEKGTISFNDICKMMTTTLPKIPESSGNH
>A0A653KEQ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas salmonicida|TrEMBL
MRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQVNEHPFDLILATGDLSQDHSPESY
QRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQVMLLDTQVRGKP
HGVLGDHQLAALDSALRQHPERHALIALHHQAVPVGCAWLDQHNLKNADDLFAVLARHPQ
QKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGWRYLTLHPDGRVA
SQVWRLPVGQFVPDPDATGY
>A0A4R3Z1J0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Biostraticola tofi|TrEMBL
MESLLTLPVAIGANIRILQLTDTHLFAGEDETLLGVNTLRSYRAVLDAVKAEQRPYDLVV
ATGDLAQDHSAAAYAHFAEGITGLSAPCVWLPGNHDFQPAMVNVLASKGITPSKHVLVGE
NWQLVLLDSQVFGVPHGELSEYQLDWLEKVLAARPERHTLLFLHHHPLASGCIWLDQHSL
RNAHMLAEALAKYPLVKTLICGHIHQELDLSWQGRRVLASPSTCVQFKPHCTNFTIDTVA
PGWRYLDLLPDGTVETEVRRLAGLEHLPDMDSEGY
>A0A2J8V5M6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pongo abelii|TrEMBL
MAQQTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKPKTARKSVSPKLSPVTSP
RNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVH
SQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALT
NLQDRAPSKRSPMCNQPSINKATITGS
>A0A7L8RHL1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinobacillus sp. GY-402|TrEMBL
MINTYQYDTDSDEIRILQITDPHLFKDAGSELLGINTCASFNQVLTEIQASPFQADLVLA
TGDLVQDSSDEGYLRFCEMVQSLGKPVFWLPGNHDFQPKMNELLNKSHGNICAKKQILAG
EKWQVLLLDSQVFGVPHGSLTEYQLDWLHDKLKAEPARYALIALHHHLLSTHSAWLDQHN
LRNANELAQILAEFNNVKGIVYGHIHQAVDGIWNGYRVMSTPSTCIQFKPDSNHFELDTL
QPGWREIILHGDGRIETYVRRIQQASFLPNMSEDGY
>A0A432EMS7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MAARKINRRQIPFAMPGRRPECEVCHIIWRGWGYNRRRMNNNKLSLLQISDFHLFSDPRA
ELMGLNTHDSLDSVLSHIRSGNRKPDLIIASGDLVHDGSSAGYQRMEKMLGSLPAPVYCM
PGNHDDKQRLRDLLGRQCSDRHNVCAPNRVDLDGWRLILLDTVVNGEKYGHISTQELHRL
EQELDSAADRQILIFLHHQPVPAGSAWLDSMQVKNAEALFDIVDSFSPVRAIAWGHVHQA
FEGERNGVRLFSTPSTCIQFAPASERFALDQTPPGWRWFELGPDGRLDSDVERLQTLPQC
DHSAEDAQGYS
>A0A2J8T624|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pongo abelii|TrEMBL
MTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRESDLSPRPELRKSRLSWPVSSCRRFDL
ENGLSCGRRALDPQSSPGLGRVMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASD
LHGEDMIVTPFAQVLASLRTVRSNVAALARLQCLGAAKQGPVGNPSSSNQPPPPAGKTGA
NCSPAPAKRNNNALGDGPHHTHITDEEAEAQRSHGSRCRDEGVRGMGSLSGGWAGP
>A0A6J3KG69|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bombus vosnesenskii|TrEMBL
MASPSNDSFFPNEGLNILDDILLSNGKTEYDVLRRRSSFEDVAVDDDENADCSALKGPQN
IEAHPLTNSVPSLIKILLVFPKDDQQMDVLATTSRRLGWSVSVAKDAEKAVEFFQNRGHE
LVIIDHRGQRAAEADTICRYGELFFKNQPNSSGVRLYILINTIYFRAIRSSPAYHNSIII
ALVKKSFLMHGEKDKIVTLDLLETGFSRALMECSHERLLINELVGIYASALLPRTQLAAA
NALYVALDRCRDMVHVTNDKHIVQFVNKISEKLLGYKTSEILGKSIADIVVYDNFVLMEQ
HISKGREFEGNMNCKRKNNQMITISCRVIPFSINLKKPTHYIYIYDTTYLSENIGSLSPT
PSQSVYSRGNMIVSQRRTSDMKSSEGRRRSSAHKLHSLQLDAPITKVISLLSNAITESTT
PDTAAQIEKAIDILKTTELYVPSLREDTDPVTTDLVGALLASPRKAWESRRSSVESTRVS
MSKTFSTTTASRMQIKSFRGPQEIAEILERCLEWNFDIFKLEILTEKRPLLFLGTTIMNM
YRVPARLGCEEKVVQNWLTVIEMNYQSRNSYHNSTHAADVLQATARFMQSERLQQILEPL
DEVATLVAAAAHDVDHPGRSSQFLCNSDNKLAILYNDLSVLESHHAALTFKLSLSDDNVN
IFKNLERDTYKQLRQTVIDMILATEMTKHFEHLAKFMNICSARMMDSPQLDDYTDTVDMS
VVLQPENVVLVKRMMIKCADVSNPTRPLKCCVEWARRIAEEYFNQTDEEKRMQLPVLMPM
FDRATCSIPKAQIGFVDFIINDMVEAWDAFIDMPEMVGYMRQNYEKWKEYNDRGISTLPD
IEKIQELPELRIYQLPS
>A0A4W2CSX2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bos indicus x Bos taurus|TrEMBL
VFQGRRSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKS
MSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINK
ATLTGKKDLGDYSFHV
>A0A673MQ54|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sinocyclocheilus rhinocerous|TrEMBL
HFDVDNGTSSGRSPLDPMASPGSGLILQANLVHSQRRESFLYRSDSDYDLSPKSMSRNSS
IASDIHGDDMIVTPFAQVLASLRTVRNNFAALTNVQQERPNNKRSPMCNPPPITKTSYTG
VVSLLSIF
>A0A2S8PV62|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus luminescens|TrEMBL
MESQFELPVVEGTTAKILQITDTHLFAGKEDTLLGINTYRSYQAVLDAILKQNADIDLIV
ATGDLAQDQSLEAYRHFAGGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGK
HWQLLMLDSQVQGVPHGELSEYQLEWMKKCLDKYPERYTVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQGYSRVKAMLCGHIHQEMDMDWNGIRMMATPSTSVQFKPHCTNFTLDTVA
PGWRYLELSVADNREFGLTTQVHRLESNEFCPDLDSDGY
>A0A8E5JKZ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Enteritidis str. 607307-2|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A6L6G189|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia sp. wls1919|TrEMBL
MDSQLKVTANNPKVIRILQVTDTHLFADTENTLLGINTYRSYQAVLDAIAEQNLPVDLIV
ATGDLVQDQSPKAYQHFAAGIERIPAPCVWLPGNHDYPPAMVGTLKIAGISSAKQVFIGD
DWQILMLDSQLQDVAHGELSEQQLEWMKQCLDEQPTRTTLIMLHHHPLPSGCTWLDQHSL
RNSHILADYLKNYPNVKAMLCGHIHQEMDENWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELTVNEQGEKVIETQVYRLNTQEFSPDFDSDGY
>A0A1N6SBR8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sp. RU39B|TrEMBL
MILETELLQAPDGSVRLLQITDTHLFGSVDSQLLGVRTADSLAAVLARIQANAHPYDLIL
ATGDLSQDHSDDSYQRFADMLAPLGKPIYWLPGNHDDGPLMTQRLYESGISEAKWLVGEY
WQIVLLDTQVRGKPHGLLADHQLAMLDHALRSHPDKHTLIAVHHQGVPVGCGWLDQHNLK
NADDLFAVLARYPSARAILFGHVHQEFDEMHRGVRLIATPSTCIQFKPLCHDFTLDESGP
GWRYLTLYPDGRIATEVWRLPPGDFQPQADARGY
>A0A5X9FD96|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Tamberma|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A656VE76|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia marcescens|TrEMBL
MESLFKLPVASGAAVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAIQAQRRDVDLIV
ATGDLAQDHSQEAYRHFAAGIAQLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLLGD
DWQVLMLDSQVFGVPHGELSEYQLEWMERCLQAYPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAILLRYPKVNTVVCGHIHQDLDLEWQGRRLLATPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>C7BKC0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus asymbiotica subsp. asymbiotica (strain ATCC 43949 / 3105-77)|TrEMBL
MESLFELPVVEGTTAKILQITDTHLFAGKEDTLLGINTYRSYHAVLDAILEQKTDIDLIV
ATGDLSQDQTLKAYQHFADGIARLSAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGK
YWQLLMLDSQVQGVPHGELSEYQLEWMKSCLDEYPERYTVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLRGYSRVKAMLCGHIHQELDVDWNSIRMMATPSTCVQFKPHCTNFMLDTVA
PGWRYLELSVTDKGEFSLITQVHRLESNEFCPDLESDGY
>A0A653CNY9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Callosobruchus maculatus|TrEMBL
QCVLETTNIITCVNEVLLLKHSDVIPLARHATCEAMYMALDKCKDIVVITDDSYKLQYIN
RACEKQLGVRQEECLGKTLQESFVTDTIQINTMGSSLLRAREWNGAMTIRRRSQETIVTS
CKAVPFNCCGKSPTHFVMVFDPALTETNILTQQRGSVHSIRRGSTDVRSVGSDYLRRTSL
AKLNALPLEAPITKIIGLIDQARDGAGTNPQVIQLLDKVEDMLRCTELYSPHVKEDNRMK
TDEPVVSDLITALLSKQPQPTFAASSRRSSNDSTAFRSSRTGLLKLPAALKELLETCLSW
EFDIFRLEDLTRKRPLQHLGMAIFTHFDVASTLNCDEKTILNWLTVIEVNYHPENAYHNS
THAADVMQATANYLEKERMKSLMDPLDEATSLIAAAAHDVDHPGKSSAFLSNSDNPLAIL
YNDVTVLESHHAALTFKLTLGDERVNIFKNLDRESYKVARSNVIDMILATEMTKHFEHLA
KFVNVFCTKSSGSETEGECPDYVPLSLPENVTLVKRMMIKCADVSNPARPLRICVEWARR
ITEEYFHQTDEEKAKGLPVVMPMFDRHTCSVPNQIGFVDYIINDMFEAWNAFIDMPELLT
YMRQNYIRWKELDEQGHTTLSDIQKLQSTMFMAPTFPTSKSTTVKGD
>A0A844WUI0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gilliamella sp. Pas-s25|TrEMBL
MRSLLKLPIRNKNYGKILHITDTHLFADEDGSLLGINSNASFLAVINEIGRNNKQFDLIV
ATGDFVQDGSKKAYARFAEQISKFNTPCVWLAGNHDNYTSMQDVFASYQLADNKIVLLGD
NWLVVLLNSQVVGQAYGFLPESELEFLQNALTEHVDRDALVFLHHHPINSRCHWLDHHIL
KNSDQFEQIIQKNVNVKGIGWGHIHQKQDYVWHHCHAFSTPSTCFQFKPECYDFQVSSDD
APGWREITLNADGSIESEVYRLADNQFLPDVSQSGY
>A0A7Y5I5Y7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudanabaena biceps|TrEMBL
MPKIDGEGFMSSSISIAQITDTHLFEDIDQYLVGIPTDRSFKAVLAEIKQNISKVDLLLL
TGDLSQDSSAASYQRLRDHLDKHEIPAYCLAGNHDDWQIMQTHLPSKYVHLKRSLNIGNW
QILLLSSVVVGAVHGYLADAELAWLDQSLNAARDRHILIAFHHPAIPIGSPWMDGICLTN
QDQFWEICDRYPQIKVVLNGHAHQDFDKIHQTTHNSVRCLVSPSTCVQFQPQNPNFQIDN
QSAGFRHLELFSDGSMQTKIHRLKHNRFIANLHAIGY
>A0A5F0JJP8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. BCA13|TrEMBL
MPSVSTVNPDAPALLVQLSDSHLFAEANGTLLGMNTRESLQRVIELVRAQQPQIDLMLAT
GDLSQDGTLESYQQFRDMTRQVDAPARWIPGNHDEPQVMALAAMHSDLLEPVFDIGNWRV
TLLDSAVPGSVPGYLQDRQLQVLAQALSEAPSRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDHERNGVRLLASPSTCIQFAPGSEEFQVSEQAPGYR
WLRLHADGRLETGVERIKGFTFTVDYGSNGY
>A0A6I2HZZ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacteriaceae bacterium RIT691|TrEMBL
MESLLNLSLAGGARVRILQITDTHLFAEKHETLLGVNTWESYQAVLAAIRASQRECDLVV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSALQDSGISPAKRVFAGE
HWQILMLDSQVFGVPHGELSDFQLEWLEQRLAESPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDRVLMRFPRVKNLLCGHIHQEMDVDWNGRRMMATPSTCVQFKPHCANFTLDTIA
PGWRWLDLNSDGTLTTEVCRLESAQFRPDTASEGY
>A0A3N4VPN0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vespertiliibacter pulmonis|TrEMBL
MYDFPDLKSIRILQITDPHLFTNEAGELLGVPTIQSFQAVLEAILQSSFEFDFVLATGDL
VQDHHSGAYHRFAQMVKLLEKPLFWIEGNHDIQPDMSEILASYSQIQPHKQILAGEKWQL
ILLDSHLANVPKGELSSAELNSLAQKLAEYPDRYTLIVLHHNILPTNSAWLDQHSLANAN
ELAEVLKPYPKVKAILHGHIHQEVDSEWQGYRILSTPSTCVQFKPNCNEFTLDPISQGWR
EITLHSDGRIETVVKRLDTNNFLPNFKALGY
>A0A369YFJ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus sputorum|TrEMBL
MQQVYELKKEATEIRLLQLTDMHLFSDPQAKLLGVNTQVSFQAVLDEVMAEPQPHFDAVL
ATGDLIQDSQVEGYDYFAQMVQPLASPVFWLEGNHDEQPQMHMKLASYPYICAEKQILAG
KHWQILLLNSQVSGCPSGYLSKEQLIWLDAKLTEHTERFCLIALHHNLLPTHCAWLDQHC
LQNTEHLAEVLAPFKQIKAILHGHIHQTVDSNWHGIRVLSTPSTCIQFKPNCDEFTLDLL
APGWRELVLKADGQIETVVKRLKTQTFLPNLEAKGY
>A0A2I2V3H7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Felis catus|TrEMBL
MQVFMAVLFLSFFHSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDS
DYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPM
CNQPSINKATITEITTLGPWRPAPVEEDEDKEAGRGSSK
>A0A7X1G9L8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas kielensis|TrEMBL
MPSVSTLTANDPVLLVQLSDSHLYAEADRTLLGMNTRDSLTAVIELVRAQQPRVDLVIAT
GDLSQDGTLASYQLFRHLSEQIDAPARWIPGNHDEPQVMAQAAVQSSLLEPLLDIGNWRI
TLLDSAVPGSVPGYLQDDQLQLLARALSEAPERHHLVCFHHHPVLIGCPWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEVDQLRNNVRLLASPSTCIQFEPGSEDFRVDTLAPGYR
WLRLLPDGRLETGVERVIGFDFTVDYGSDGY
>A0A7F8RE88|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Leptonychotes weddellii|TrEMBL
MAQQTTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQQEKSKPARKSVSPKLSPVIS
PRNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFV
HSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAAL
TNLQDRAPSKRSPMCNQPSINKATITERWKLCRYNTKHLEEKKPSQSLLKRDS
>A0A521WZ52|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacter sp|TrEMBL
MSHSPACISILQLSDLHILAAPEDKMLGINTEHYFHACLEQAVRLRSQRADTEQRHFDLI
LLTGDLTQEPCPESYRRILTRLEAYKTPCICLPGNHDDYELMLRILNTDSINCRKQVLLD
NWQLICLNSQIPGKPGGRLSKEELDFLENCLSKNPDRHAFIAVHHHCLETKSPWMDTMII
ENSQQLLAIVDKYPQVKAITTGHIHQVMDIKTANLRIMGAPSTCFQFTPRTNGFSVDNTA
PGYRLIELYTDGRVESEVVRLPEPLIGLQTNKHGY
>A0A7W3A2K8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella sp. RHBSTW-00465|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQILLMDSQVFGVPHGELSDFQLEWLEHKLAEVPERYTLLLLHHHPVPSGCGWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHSANFMLDIVS
PGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEGY
>C6C447|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Musicola paradisiaca (strain Ech703)|TrEMBL
MESLLTLPVACGARIRILQITDTHLFAGEQGTLLGVDTYRSYYAVLDAIAAQRLDFDLIT
ATGDLAQDHTHEAYQHFAGGIRRFQVPCVWLPGNHDFQPAMVDALEKAGIAPSKHVLLGD
DWQVILLDSQVFGVPHGELSDYQLEWLERRLSAQPGRHTLLMLHHHPQPSGCSWLDQHSL
RNAHSLDALLSRFPQVKTVLCGHIHQEMDIDWNGRRLLATPSTCVQFKPHCTNFTIDNVA
PGWRYLDLLPDGSVETRVCRLDGCEFLPDMDSDGY
>A0A2N7KL04|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIEPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHSNVKAVLCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTQVRRLPNGQFSPDFDAGGY
>A0A0H3MKY5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O7:K1 (strain IAI39 / ExPEC)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>U3CHH8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio ezurae NBRC 102218|TrEMBL
MEQQIVAAEETVQLLQITDTHLFADDEGCLLSVNTGSSFQAVVEDIAARNPYFDAIVATG
DISQDHSIASYERFANGIEKLVKPCYWLPGNHDLKANMGSVFPSTQINEVEHVFAGEYWQ
LIMLNSQVEGLPHGYLEQQQLDLLDEKLSQYPERHTLVLLHHNSLPIGSTWLDQHKLQKA
EQFWNVLEKHSNVRAVVGGHVHQDFEEEYNGIKVLATPSTCIQFKANTHEFALDSLPPGW
RHLQLHKNGHLETQLYRLAEGCFVPDFEAQGY
>A0A2G4AX54|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MTTVNILVISDLHAGITQDSVSDTKLILRDQHNVFGDKLIDYIKGLDEKIDYLVCAGDIA
NQGCKDSFQAGWEYVNKMAQELSISDILCVPGNHDHQSRPPEDNKYGFSPKHELQFITPP
FPFSCYHKNTHFWAWNWELTSTEKCNVLSINSSAYHGYGSEYKHGRVALEVTDQIKQKLT
SSAVSRKPFNVLLTHHHPKKMDFVDLESDSQAMEGAEYLLRALENADLGPWLIIHGHKHY
AQIGYANSQIQGSQLVLSAGSLSAVLYETIENRTSNQFYVLSIEPEKSEYLGKVVGKFKT
YEANKLQEWQPSKSNNLPANGGFGSIYTPDQVVNDLKAQISKENPFLEGVELSQFKEKIE
HFTPDEISRLNARLHSNKFSVVRCQDNHIIEVGLGNE
>A0A7W4FY26|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. SG44-6|TrEMBL
MLKDAVHYSVAENEPVRLVQVTDPHLFADPEGQLLGVNTAQSLQAVLNTFIATQYPAHLL
LATGDISQDYSPESYQHFVHKIEMLDLPCHYLPGNHDDPRLMSLRMQGEKVFGQQRIIIG
NWLILMLDSTVSGKPGGYMGEQQFALIDAAIKAEPNKHVLLVMHHNPILMQCAWLDQHCM
MNGADFLQRTSRYPQVKGILWGHVHQQVDRTHLGPHGHIPLMATPSTCIQFKPLSSYFAL
DHLQPGYRLLELAGDGSIRTNVYRVPGNRFAPDNEASGY
>A0A2S6U859|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alphaproteobacteria bacterium MarineAlpha3_Bin4|TrEMBL
MILAQITDTHLMSPNPAEPRAAARARALKQSVADINSLDPRPDAVIHTGDMTQTAAATEI
ALACELLAPLAMPLYVTPGNRDGRQALIGAFFGDDCVADGGFVHYAVNHHPVRLVAIDSL
SGNNNKGNFCRARLDALDTTLAQAPARPTALFMHHPPFDVSTSLYPFQYNCRQAVAELAT
VVSRHDHVVRIFTGHSHRPYVAHFGGTVASTMPSVAPDLRQGDYPAAMADRPVYQLHRFD
ARGGFVSETRLVDA
>A0A5F0JU70|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. A11|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYNALQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLTGAKFRPDTASEGY
>A0A5N4FNR6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium damselae subsp. damselae|TrEMBL
MLTYSLPPRQSDSVVLLQITDTHLFANDAGSLLGVATKDSFHAVLAAIDHQARPFDAIIA
TGDISQDHSTESYQHFAQGIARWQQPCFWLPGNHDYQPSMKAVLPSPQIKPCEQVLLGEH
WQMILLDSQVPGVPHGELRAEQLDMLDRALAAHSERHALVLLHHHPLAAGSAWLDQHQLH
NADDFWQVLARYPAKVKSVLCGHIHQELDCMRQGVRVLATPSTCIQFLPDSDDFALDSKA
PGWRYLELTPQGDVHTQIHRLANDQFAPDLNSAGY
>A0A8C4LIV3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Equus asinus asinus|TrEMBL
CFQGSTFFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPK
AMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKCNLCNFPGVIGR
IGCHE
>A0A8C4PN03|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Equus asinus asinus|TrEMBL
MLTAVSFLLLHYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDY
DLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCN
QPSINKATITGGSCPWKIITWHFSHPMLMVDRQN
>A0A7T7WI18|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter variabilis|TrEMBL
MTSEKFNPASTQEWTIIQISDTHLMDQPNLEFANMNPEQSFHEVMQHIQHNFPEMDALVH
TGDLAQVPIAETYTRYLKYIQSCQVPYYQIPGNHDDIKVFPFYQDRDQAHAIHFGNWALI
LLNSAVQDRIDGWVEQAQLEQLDQLLLEYRNQHVVVACHHHPFAMKSHWIDQHRLKNAED
LKDVLARHQNVKLVLFGHVHQDSWNEWQGIQFLSTPSTSVQFKPKSNEFALDQAAPGYRV
LHLKQNGEFDTHIERVALSQQNINTEISGY
>A0A1K9ZX75|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moritella viscosa|TrEMBL
MGADISKLTAKHNVINLLQVTDTHLFATAEKDLLGVKTQQSFSHVIDAILQNQQPFDAVL
ATGDISQDNSIASYQYFAQHIKRLDKPCYWLPGNHDNIPLMADALKSEGVLSDKYKVVGD
WQIILLDSQLTGSPSGYLSPEQLTLLDEQLSLHPDKYALVVLHHNTYPVGCKWLDQHILR
NPEAFLAVLAKHPKARHVLFGHVHQQLDETYDGIHFMASPSTCFQFKPHCDEFTLDARAP
GWRYLQLHSDGTVNSQVWRLSNHDFNPDLESKGY
>A0A8F8DKF1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. TC-EC600-tetX4|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A221V3L9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arenibacter algicola|TrEMBL
MALLQKIKLILILITLIGCGSKEPKTSADQDLAIGIIADCQYCYCESSPTRFYKNSPEKL
QNAVDSLNSSPLDYAIHLGDFIDRDFSSFDTVGPIWSTLKTKKYQVLGNHDFSVADSLKP
LVPHKMNLKQRYYSFVEQNWRFIVLDGNDLSYQGAITPEKLAQTDSLFTLLSNSKPPNLQ
TWNGGLSQEQLEWVESELKLAQQNKENVGFYCHFPVLGEDKVHRLWNSPQFLSLIDQYSN
VKFYFNGHNHNGDYAERRGVHYLTFKGMVDTEITSAFAKVRITTDSILIQGHGREPSRSL
NISVR
>A0A7U9RRU0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lachnospiraceae bacterium|TrEMBL
MSRKDRKITIFILAIFILVLLGLLLFWQKGTNDSNKEVVSVESEEMSQSESTTEADIEQE
SDTPQVVYPKPDYTFVTEDVTIPIEGVEQEYKFAWVSDLHLISDHEAGELLGDVHIEYLD
AIQRRYEELSVTQEGVHAEELWPEIIKYLNYMQFDGVIFGGDIMDYCSNSNVTMIKEGLD
NLQIPYIYVRADHDYGTYYGGVFFTEDEARKLHQTIDGDEIAYKFWDRDTFMVLGIDNST
KDMPDYYLNMVADVYSRGRPVIMVTHVPYESKIDQTLAECSMQVRNKIYYWSDASEQYKP
NNITKQYLDMIYSEDTMVKQVLAGHLHESWDGMLTQQVPQHIFAPAFRGNIGIIHIVPKK
>A0A4R0EAE4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. ANC 4779|TrEMBL
MTLSNYNDDQHDWTIIQISDTHLMNQEDLEFVSMNPEQSFHAVMKHIQQQYPKVDAIIHT
GDLAQVPVKETYSRYLAFMQHLGIPFYQIPGNHDNIDLFPFYHNQNQVHAIHFGRWSIVL
LNSAVRGKTDGWIEDVQLQQLDRILSKFQQQFVVVACHHHPFDMQSKWIDQHKLKNTENL
TDILAKHSNVKAVISGHVHQDSLNAWQNIQFFSTPSTCVQFKPLSDDFALDQEAPGFRVL
HLKANGELQTEIYRTETDQQKINIEISGY
>A0A7H2PQM2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter seifertii|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIKQILKQHPEADAIIHT
GDLAQAPTPLTYKRYINFMQTLGLPFFHTLGNHDNVDHFPLHNENHQEPVVVGLGNWRII
MLNSAVKGKIDGHLSSEQLKNLANLLEKFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFKNVKALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSKDFALDQNAPGYRY
IRLNNDGTFETKVFRLENFKTLINTDISGY
>A0A8C6XT50|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Naja naja|TrEMBL
FFYGARKNCYNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSM
SRNSSIASDIVNFYALCLLQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATI
TGKIP
>B4GHU7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila persimilis|TrEMBL
MGCSPSTLPQFRLRLRRRPTPTPGPTAANSVPLSLDATEKDGSRLFCIKLRRSRLRRCSC
GGVALQQGDGNVNGSTAGSATCGSGTGDNLCHQVLLNPLQAKNEADYEKLSTGKKDSIVT
VAALGNFTHSVVRRATGIPVPVLVPASVSGAHTSEESVESASAPSGCNCVGQAGVGVHVK
VGMDGPVGVGARQTPAMEATTTTATAEGSRDSLTRPASESELAVGTGTGTSGTSSSGGGG
NNRPGHRKSSLALALTPEDDPMDVYQVSVHVHIRIHWIQREVARHAEMRNCLPKLTNVFR
RKSSAKSSATGNRANHSNDCLSDSDSEQYTAVAMSGGALAIPSPQSDQPHDNNNKRPPHT
DGDSSYSRLISGSHLETVAVAPNVRIRTMDESSFTEMRVEAISGQAPGPTSGPTPGPARL
SVPIPGRNSISLPFAGLGSSKTPEEMELEYEANVKAEGGDIVTPLRRNTNTTGTRPHSMA
QNGGRSASLQPEIVEAIRNLDVQGLFFNNLAMEDGDSESDSQCHEDAVVLRRKVAGLERK
SCSLYERRMPKMPKLHLMVAGKKPQPQPQQQPEDDDDEYKVFQRNLMDLKYPTVLPPNPQ
LKALLVFHKSDSICEAVASACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARS
SKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMC
SVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLNMRLD
EIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMHVRVVPVACIGSAPTH
LIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPL
EAPITKENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSS
RRSSNDSIIRTGSSTRTATIVPAKMKANPIIMELLEESLSWDFDIFKLEEITDYHPLLYL
GMEMFRRFDVFATLNIEENVCKAWLAVIEAHYHKSNTYHNSTHAADVMQATGAFITQLTN
KDMMVMDRMEEAMALIAAAAHDIDHPGRSSAFLCNSNSALAILYNDLTVLENHHAAITFK
LTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPREHNPQ
SDEETAILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFD
RATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLADVM
AMQPPMVKLANSK
>A0A6P5VK85|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila obscura|TrEMBL
MIISSQPNLAGSTPTTTTTAIATATATLPVPVPVPVPVPASVSGAHTSEESVESVSSGCN
CVGQAGMSVGVHVDVPVGVGTRQTPAMEAKTTTTTATVEGSRDSLTRPASESELAVGTGT
GTSGTSSSGGGGNNRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPQLKALL
VFHKSDSICEAVASACQRHQLDVTLVKSKEEALDTLHKSYATAQCYHLIIIDARSSKNLD
AEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCIAETTNLAMCSVELK
QILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLNMRLDEIISK
PLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMHVRVVPVACIGSAPTHLIFNF
DVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPIT
KIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPS
VYSSRRSSNDSIIRTGSSTRTATIVPAKMKANPIIMELLEESLSWDFDIFKLEEITDYHP
LLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADVMQATGAFIT
QLTNKDMMVMDSMEEAMALIAAAAHDIDHPGRSSAFLCNSNSALAVLYNDLTVLENHHAA
ITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPRE
HNPQSDEETAILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVM
PMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTL
ADIMAKQPPMGKLANSK
>A0A4W5R470|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hucho hucho|TrEMBL
MLNRELTQLSETSRSGNQVSEFIANTFLEKQQDVEIMSGPLKDKDKKKRPMSQIVAVKKP
VLSPSLAPTQIPRFGVTTLHEGLLATEFEDINRWGLDIFKIAEYSGNRPLTVVMYSIFQE
RELLKNFKIPADTFVTFMMTLEDHYHTDVAYHNNIHAADVVQSTHVLLSTPALEAVFTDL
EIMAALFSSAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEDNCDI
FQSLSKKQGQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLDIYRQWTDRIMMEFFTQGDRERDKGMEISPMCDKHNASVEKT
QVLYCTMQVLSTGCMFSKPL
>A0A752MKC6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. houtenae serovar 21:z4,z23:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A3Q0T051|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Amphilophus citrinellus|TrEMBL
IDSLSRSPSSGHSRNCSFWYFALALFFTENGVSPGHTPLGSQSPSLTLHTTFPQGQRRES
FLYRSDSDYDMSPKTVSRNSSLASEGHTAEDFIVTPFAQVLASLRSVRSNFTILANVSTP
TVKSVSPKCPVVST
>A0A399FCI8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Meiothermus granaticius NBRC 107808|TrEMBL
MLAAYRFGISRYQRPLQGLTRPLRVAQLSDLHLGFWIQKGSLEAWIRATNAEAPELVVIT
GDLTDSSRPHQVLPALPVLGQLLAPLGVWAVWGNHDYRFNGYRIKERVEGVPPPRTFLSA
FDPPQKVPMYPPEALAARLQEVGVEVLRNRGVSLREDLFLAGVDDLWHGEPDVVAAFRGA
PPQSARLLLAHNPDYLYQVAQAAQRPSFTLCGHTHGGQIVLGGYGPVFTSSQYGQKFAQG
FVEDPVPAFVSRGLGVSSAPLRYRCDAELVIFEFVPL
>A0A7S6YPR0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. Ac-14|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPHLEFVGMNPEESFHAIIQQILNKHPETDAIIHT
GDLAQAPTPITYKRYIQYMQTLGLPFFQTLGNHDNVDHFPLHKENHQEPVVICLGNWRII
LLNSAVKGHIDGHLSAEQLENLTALLEEYADNPILLACHHHPFAMKSKWIDHHKLQNSNA
LLTALTPFKNVKALVCGHVHQDSINIWQGVEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLKNDGSFETEVFRLENFQGHINTDISGY
>A0A4Q9GI33|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. BGI-2|TrEMBL
MPSVSTLTTADSALLVQLSDSHLFAEADGTLLGMNTRDSLQKVIELVRLQQPQIDLIVAS
GDLSQDGTLESYQLFRDLTRQLDAPARWIPGNHDEPQIMAEAAVQSALLEPVVDVGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCFHHHPVSIGCLWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDQDRNGVRLIASPSTCIQFEPGSDDFKVGEQAPGYR
WLRLLPDGQLETGVERVTGFDFQIDYGSNGY
>A0A1E5BJY2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio genomosp. F10 str. ZF-129|TrEMBL
MKLSPSPAEVSPIKLLQITDTHLFAPADGDLLSVNTLDSFQAVVSMIQDSGVNFDSILAT
GDISQDHSVESYQRFAEGIAPLKQPCYWLPGNHDYQPNMGTVFPSPQIQHIEHLYIGEHW
QVIMLDSQVVGMPHGRLSDRQLDLLDEKLSANPNRHTLVLLHHHPILVGSAWLDQHTLKD
SELLWQVLDRHSNVKAILCGHVHQDMDREFNGVRVMATPSTCIQFKPNSDEFALDKRAPG
WRELDLYDDGQLVTQVQRLPNDRFFPDFTAGGY
>A0A3A8G6R6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter cumulans|TrEMBL
MPLINNNDQHKHDSVFDWTIIQISDTHLMDQHELDFVSVNPEQSFHEVMHHIQQQVPHID
AIIHTGDLAQVPVAETYSRYLQFMTGLDIPHYQIPGNHDCTEIFPFHLQQDQAHILHYGA
WSAILLNSAVKDKVDGWISETQLQQLHQLLSDHPQQHILIACHHHPFAMESAWIDQHKLK
NATHLMDVISQHSNVKIVICGHVHQDSMNTWNNIQFLSTPSTSIQFKPHSQTFALDQVLP
GYRVIRLKNNGEFETEVHRVALSQPQINVEISGY
>A0A5I0BFW8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Koketime|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A3N4NTZ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. RIT388|TrEMBL
MDSLLTLPAANGAGIRILQITDTHLFAGKNESLLGVNTWASYNAVLKAIVAQQREFDLII
ATGDLAQDHSVEAYQHFAEGIARLPQPCVWLPGNHDFQPAMVDTLAEAAIAAQKHVLLGE
HWQLVMLDSQVFGVPHGMLSDYQLEWLEKTLAIYPQRHTLVVLHHHPLASGCTWLDQHSL
RNAHQLDAVLQHYPLARTLVCGHIHQELDLAWHDRRVLATPSTCVQFKPLCTSFTIDTVA
PGWRWFTLYPDGTLDTEVNRLQTDAFRPDLDSDGY
>A0A7K0DG45|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nocardia aurantia|TrEMBL
MILLAQLSDTHFDLHERNAERVEAVMAYLADLPRRPDAILVTGDITDTGERGQYEQARTA
LLADLEMRFMPGNHDDRAGLREVLLREPPTTGPLNQALRLPGVTVALLDSTVPGRSDGEL
SAGTLAWLADMLRDTPAADAVLVALHHPPLPMYSTVVDPIRLTNPEPLERLVAADDRIVG
VISGHMHAMGTTLFGGRPLVVAPSVASLIGGVWEVARPGQVPIDYGPDPSILLHVIEDRR
LTTIVRTVPMGGRIAVQPR
>A0A347USX3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio alfacsensis|TrEMBL
MQSSSDSIKLLQITDTHLFAADEGSLLSVRTADSFYAVVQEILKRQVQFEYILATGDISQ
DHSAESYQRFADGIAPLEKDCFWLPGNHDYKPNMGSVLPSSQIQTVEHLYLGDHWQVILL
DSQVVGVPHGRLSDQQLSLLEEKLAENANRHTLVLLHHHPLLVGSAWLDQHTLKDADAFW
QVVDRFDNVKGIVCGHVHQDMNVVHHGIRVMATPSTCVQFKPNSDDFGLDTLSPGWREIE
LHQNGDITTQVNRLGEGQFQPDFTSNGY
>E5YJ69|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacteriaceae bacterium 9_2_54FAA|TrEMBL
MESLFQLTVARGAPVRILQITDTHLFAGEHETLLGVNTHRSYHAVLEAIHAEARPYDIVV
ATGDLAQDHSVAAYQHFANGIATLNKTCLWLPGNHDFQPAMVDTLANAGVNPAKHMLLGD
YWQIILLDSQVFGVPHGELSDYQLEWLERTLSLYPQRHALILLHHHPLPSGCTWLDQHSL
RNAHMLGEVLQHYPLAKTLLCGHIHQDLDLQWEGRRLLATPSTCIQFKPLCTNFTIDTLS
PGWRYLDLHPDGTLTTELHRLDGTEFRPDLDSDGY
>A0A7T0DUU3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter mori|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYNSLHEAGISPAKCVFAGD
QWQILLLDSQVFGVPHGELSEFQLDWLENKLAAEPSRHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLVKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLSGAKFRPDTASEGY
>M7CDG5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Morganella morganii SC01|TrEMBL
METPLHLPVADGAAVRILQITDTHLFAGETDTLLGINTLHSYHAVLDAIVKQQLPADLIV
ATGDLVQDQSTRAYQRFTDGIARLPAPCVWLPGNHDYQPSMAQELAAAGISPSKQVLLGD
QWQILLLDSQVQSVPHGELSDDQLIWLDNCLAQQPDRHTVVMLHHHPLASGCTWLDQHSL
RNSHMLAEVLTRYQNIEGILCGHIHQDLDVMWNGIRMLATPSTCVQFKPHCTNFTLDTAA
PGWRYLELTTGDNPSLTTQLFRLDTDEFSPDLGSDGY
>A0A6I1QQR4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. B1Z05|TrEMBL
MEPHIVVTEETVQLLQITDTHLFADDEGCLLSVNTGLSFQAVVDDIAAHNLPFDAIIATG
DISQDHSVASYKRFANGIKKLLKPCYWLPGNHDLQANMGKVLPSEQINEVSHVFAGDYWQ
LIMLNSQVEGLPHGYLEQHELDLLDEKLSQHPERHTLVLLHHNSLPIGSTWLDQHKLQKA
DQFWNVIEKHSNVRAVLGGHVHQDFEQDCNGVKVIATPSTCIQFKANTHEFALDSLPPGW
RHLQLHKDGRLESQLHRLDEGCFVPDFDAQGY
>A0A2S4SK80|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae complex sp. ECNIH11|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLTGAKFRPDTASEGY
>A0A8I0YLF7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas juntendi|TrEMBL
MHADHPRPVHVVQLTDAHLFADPAGSMLGLKTRESLGHVVAQVRREQPLVDLLLCTGDLS
QDASVASYEAFRELTAPFGVPSRWLPGNHDEARIMAEVAPELVQAVTDIGAWRIVMLNTA
VHGATHGLLGDDQLAVLEAALKGAGGRHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDII
EGYPQVRALLWGHVHQEWDEVRNGRRLLATPSTCIQFAARSEDFKVSEEQPGYRWLRLHA
DGRLETGVERAWDFEVKLDFDSPGY
>A0A7W2KGI0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas juntendi|TrEMBL
MHADHPRPVHVVQLTDAHLFADPAGSMLGLKTRESLGHVVAQVRREQPLVDLLLCTGDLS
QDASVASYEAFRELTAPFGVPSRWLPGNHDEARIMAEVAPELVQAVTDIGAWRIVMLNTA
VHGATHGLLGDDQLAVLEAALKGAGGRHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDII
EGYPQVRALLWGHVHQEWDEVRDGRRLLATPSTCIQFAARSEDFKVSEEQPGYRWLRLHA
DGRLETGVERAWDFEVKLDFDSPGY
>A0A250B362|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gibbsiella quercinecans|TrEMBL
MESLFKLPVASGAKVRILQITDTHLFAGKDESLLGINTYRSYLAVLEAIKAQQRGVDLIV
ATGDLAQDHSQAAYRHFAEGILQLPAPCVWLPGNHDFQPAMVDALAAAGITPSKHVLLGD
NWQVLLLDSQVFGVPHGELSEYQLEWMERCLQAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHTLGEILLRFPKVNTLLCGHIHQEMDIAWQGRRLLASPSTCVQFKPHCTNFAIDDLS
PGWRYLDLLPDGRVETQVYRLDNDDFRPDMNSDGY
>A0A2H5XDP1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR17|TrEMBL
MTPEWLMAFTAGALLGYGVWESFQVRLQRYTIANAKVPATRNPLRIAHLSDLHLSRFGYK
ERRAVALIAQWRPHCIALTGDVTAWRRALPAVQEFFRALTAIAPVYAVEGNAEAANALTE
TLATLLRRCGGYWLRNEAVPFGDGVWVAGTDDPHRHRADAAKALASVPDDAFCVLLTHSP
DIIVQPAALKADLILCGHTHGGQIRLPFIGALYIRARRIPRRYAWGCHPLPNGTVLITTC
GVGTTRLPLRFFCPPEVVGVAVQSP
>A0A8E2LX39|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli TA464|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPGRHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A8D4S5Q7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNVAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLGKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAEFFPNMQEEGY
>A0A5C6H1I6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNVAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTQVKRIQQAEFLPNMQEDGY
>A0A8D4UDC6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDERAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLGKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTQVKRIQQAEFLPNMQEEGY
>A0A8G1T6J3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLGKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAEFLPNMQEDGY
>A0A2T8TF05|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGETRVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A3W7Z8T9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A378DK75|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pneumoniae subsp. rhinoscleromatis|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A556VYB6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bagarius yarrelli|TrEMBL
MKDCLSARIAMQERIERASASVCLYTDDSYQKLAVETMEELDWCLDQLETIQTYRSVSDM
ASNKQCDERMSGEGWHYWLYWHMVQSCSDVPACTDRADPPVQLQLQLRLSWTTLLDHPPA
QDMETKQRSVSAESRDVDFNLLFAR
>A0A556U386|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bagarius yarrelli|TrEMBL
MDWHREPTGKFIPCSFRVYKGMKRKHLLRSYSFDVDNGTSSGRSPLDPMTSPGSGLILQA
NFPHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDMNNHLQRPGLVSRRSEPVISGTDIV
LSELIKKRTYAQVRTHAHDDSAHTCAVNRLEATTSIASTTQRLSHGDDLIVTPFAQVLAS
LRTVRNNFAALTNLQQERSTNNPVKRLKTDHPLPSCLPPEEAYQKLATETLEELDWCLDQ
LETLQTRHSVSEMASNKVKQAAFKVGLAVAGTSERPNQDGHPRDALSGKCTQTTRYHMSG
MGRILHPNAPGLIILISGHDTLVLDTPPPLSFSLSALLTAQCLRSMIVWVIVMLWRIIFG
RCIITTDRFSQPEESETFQTVQVKVITAIGENNTQVLSYIYFKCNRFKRMLNRELTHLSE
MSRSGNQVSEFISSTFLDKQHDVEMPSLHTQKEKEKKKKPMSQISGVKKLMHSTSLTNSN
IPRFGVKTDTEDSLAKELEDVNKWGLNVFRVTEFSGNRPLTVMMYTIFQERDLLKTFKIP
LDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALELLQEENCDIFQNLTKK
QRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQLWQQCRL
QGSYRSHGRYSEWARTPVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERG
MEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIP
QSPSPAPEQNDESGRAVAPNTTDKFQFELTLEEDGETDTEKDSGSQAEEEEEEEEEEEEE
DSKTLCTQNSECTEIPLEEEGQEEGQVCKEASGEPSMVEEEEEEEEEGT
>A0A4Y8JAQ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. F01002|TrEMBL
MPSVSILTTADSALLVQLSDSHLFAETDGTLLGMNTRDSLQKVIELVRLQQPQIDLIIAS
GDLSQDGTLESYQQFRDLTRQLDAPARWIPGNHDEPRIMAEAAVQSALLEPVVDVGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLCEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPD
ALFAVLDRFPQVRAVLWGHVHQEIDQVRKGVRLIASPSTCIQFEPGSDDFKVSDEAPGYR
WLRLLPDGRLETGVERVTGFDFEVDYGSNGY
>A0A2S6SS18|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alphaproteobacteria bacterium MarineAlpha5_Bin5|TrEMBL
MLKFIIISDTHLVPDNENCNGLDSFERLNLAIESINNDHPDAEFCIHAGDITDRGDIESY
ERFKKIIPKLKIPIYLTIGNHDNRNNFKKVFNEKYSDENGFIQKTIDIKDQRIIILDTFD
KNLLGEGKLCEIRLKWLKNHIQQNNELPTTIIMHHHVAKIKSPYIDLIALENPDEFFNTV
KTHSNIRHIISGHVHISSTTFQNNIPHTTIGGSHFTHSVKNFFTEFNYSLSELKKMKENN
QINNNMIKEMSDTYDNIVILEGPSQYGVVLSDNFSTTIHFHNYIEKYKRLPQSETKLEYY
S
>A0A5E4AHN0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marmota monax|TrEMBL
FDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSI
ASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSK
>A0A0S7HKN6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
MLNRELNHLSEMSRSGNQVSEYISNTFLDKQNELELPCPVQKVRKRKQNQQQQQQQVGMM
TQISGVKKVNHTSSILGNVGNRFGVKTDQEELLSKDLEDINKWGLNIFKVTEHSHNRPLT
CVMYKIFQERDLMRTFKIPPDTFVTFMLTLEDHYHSDVAYHNSLHAADVAQSTHILLSTP
ALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFK
LLQEDNCDIFQNLSKKQKQTLRRMVIDMVLATDMSKHMNLLANLKTMVETKKVTSSGVLL
LDNYTDRMQVLCNMVHCADLSNPTKPLDLYRQWTDRIMDEFFHQGDREREKGMEISPM
>A0A3M0KCJ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hirundo rustica rustica|TrEMBL
MRERSGTSGSAGSGGPAMERRPQRQPDYMSVCLFAEEPYQKLAMETLEELDWCLDQLETI
QTYRSVSEMASNKVSPRAAPG
>A0A0S7FT03|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
MTRPTSLPFGAPPRIDITPVDPECFDVENGPSASCSPLDPQASPGSGLVLHTNFPGHNQR
RESFLYRSDSDYELSPKSMSRNSSIASELHGDDLIVTPFAQVLASLRSVRNNFTVLTNVQ
CASSK
>A0A5C4PJ76|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurellaceae bacterium USgator41|TrEMBL
MRTTFLHHSDKLPVRFIQVTDPHLFADKKAELLGINTFDSFKAVLSEIQQTPFAFEFVLA
TGDLTQDNNPEGYRYFSEEISQLQKPVFWIPGNHDYQPHMVETLNRYPEFISPLKHIIVN
NNWQILMLDSQVLNVPHGYLNQYQLDWLIAKIEQYPDLYTLVVLHHHIAPTRSAWLDQHN
LRNTSEFLSCLQQHRHIKAIISGHIHQEMDTQWNNYRILTTPSTCIQFKSDSYHFNLDIL
PPGWREFELYPDGSLITQVKRLKQNLFIPDFNISGY
>A0A853QYW5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio ordalii FS-238|TrEMBL
MNVSPTLDNSDSIKLLQITDTHLFAPDDGSLLSVNTVDSFHAVVAEICAQHVEFDAILAT
GDISQDHSAESYLRFSRGISSLEKTCFWLPGNHDFKPNMGAVFPSEQIQQSEHVLLGEHW
QMVMLDSQVVGVPHGRLSDQQLALLDEKLSTHHQRHTLIVLHHHPLLVGSAWLDQHSLKD
SDAFWNIVTQHRNVKAVLCGHVHQNMDKLHHGVRVMATPSTCVQFKPNSDDFALDRTSPG
WRELTLSADGQIETQVKRLANGAFQPDFNANGY
>A0A2S5AHP8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Avibacterium endocarditidis|TrEMBL
MVNTYTYPTDNDVVRLVQITDPHLFKDENGELLGINTQASFNQVLSEIKQSDFDYELVLA
TGDLVQDSSSEGYLRFCETVQCLEKMVFWIPGNHDFQPKMFDILNHNNGNINPLKHLLIG
EHWQILMLDSQVFGVPHGQLGQYQIDWLLSKLKDYPERYSLVVLHHHILSTNSAWLDQHN
LRNALDLAYTLSPFNNVKGILYGHIHQAVDSEWKGYKVMATPSTCIQFKPDSNSFALDTL
QPGWREIELYNDGRIETRVKRIQQATFLPNMLGEGY
>A0A846AD95|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Okeania sp. SIO2C9|TrEMBL
MIFQPPVLVAQITDTHLFADSIQGTMYGLPTESSFVKVLEKLKQLQPQPDVLLLTGDLSQ
DETSESYQRLASLLSPLNIPTYWIAGNHDHLPTMERVLNSAPISAKKSFEMGGWNFFLLN
TNVPGCVYGEISPESLEWLEYNIKMTGNKPVLIALHHPPVKINSEWMDKILLHNPENLLS
IINRYPQVKIVLSGHIHQEFAKEINGINYLSTPSTCIQFQPGNPKFFLDKQPPGLRLLTL
YPDGNYITKIERVNYIYECDMAASGYS
>A0A6J1Q1Z8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Temnothorax curvispinosus|TrEMBL
MASPPNEYFFPSEDEDSLEDELFPNHLFGKTDALDIVAEKDEKTPFQDSTLDENGDYLTI
KGPQDLSNYLLTTNVPSIVKILLVFSKDDPQLDILANTARRLGWSVSVAKDAEKAIELFQ
NRAHELVIIDHRGHHAAEGDAICRAIRSSPVYHNSVIIALVKKSYFMLDEKDHIVALNLL
ETGFSRALIECSHEGILINELVGIYTSSLLPRTQLAAAHALYLALDRCRDMVHVTNDKNI
VQFLNKVSEKLLGYKTEEMMGRNLSEIVFYENSALMEQQLAKGREFEGNMNCKRKNNQMI
TINCRIIPFCITLKKPSHYIYVYDTTYLSENSAPISPASSPLHPPLKTSILSNARKSSDV
RSGVSEGRRRSSLQKLHTLQLEAPITKVITLLSNAVTDTTNPETAAQIDKAIDILKTTEL
YVPHLKEDRAMYSDPVATDLVGALLASPRTAWESRRSSSDSARLSTIKAIAYPANSRVQV
KNFRGPQELMDILDNSLDWNFEIFKLEVLTEKRPLVFLGLTIMNLYQVPATLHCDEKTLQ
NWLAIIEHSYNAENSYHNSTHAADVMQATARFMQSKRLKEILEPLDEVAALIAAAAHDID
HPGRSSQFLCNANSRLAILYNDLSVLESHHAALTFKLSLSDDSVNIFKNLDRDAYKLLRQ
NVIDMILATEMTKHFEHLAKFMNVCSARIGDGQETYSDSLDMSVVLQPDNVILVKRMMIK
CADVSNPTRPLKCCVEWARRIAEEYFNQTDEEKKLKMPVVMPMFDRMTCSIPKSQIGFVD
YIINDMIEAWDVFIDMPEIVGYMRHNYEKWKEYNEQGISTLQDVEKLQQHPEMQIPRLS
>A0A8H9SDN6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESPLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7Z9ERA0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MYPDNTRPVHVVQLTDAHLFADPAGSMLGLNTRDSLRHVVAQVRREQPLVDLLLCTGDLS
QDASVASYEAFRDLTAPFAVPTRWLPGNHDEARVMAQVAPQLVQAVTDIGAWRVVMLNTA
VQGATHGFLEDDQLALLETALEEAGGRHCLVCLHHQPVDIGCAWIAPIGLRNALALFSVV
ERYPQVRALLWGHVHQEWDEWRGGRRLLATPSTCIQFAARSEDFQVSLEQPGYRWLRLHA
DGGIDTGVERAQDFVVALDFDSPGY
>A0A3M8T3N9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MPQPDQSRPVHVVQLTDAHLFADPAGSMLGLKTRDSLRHVVAQVRREQPLVDLLLCTGDL
SQDASVASYEAFRELTAPFAVPTRWLPGNHDEARVMAQVAPELVQAVTDIGAWRIVMLNT
AVPGATHGLLEDDQLAVLETALREAGERHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDI
VEGYPQVRALLWGHVHQEWDEVRDGRRLLATPSTCIQFAARSEDFKVSEEQPGYRWLRLH
TDGRLETGVERAVDFQVKLDFDSPGY
>A0A5I9BD27|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Eko|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A4Y8V3Y4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium LSUCC0112|TrEMBL
MQKASREFREKPLRLIQITDTHLYRDPRAVLLGLNTHESFEKIVDLIARTRGTPDVIVGT
GDIAQDASRESYQRFAEIVSRLNAPFYWIPGNHDNRKVMLALTDYPNAFDTQLIFGNWQI
LMLDTSSPGNVHGVLSDAELARLQQQLSQLPAGVQHSMICLHHNPVPGTASWMSDIGLKN
ADAMLAILKQYPATVRAVVYGHIHQTLDFEHEGFRFFCTPSTCIQFKPYVEEFALDMLAP
AYRWFDLYADGRLETAVERLQDYVIKVDMNAGGY
>A0A7H5RAW2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MYPDNTRPVHVVQLTDAHLFADPAGSMLGLNTRDSLRHVVAQVRREQPLVDLLLCTGDLS
QDASVASYEAFRDLTAPFAVPTRWLPGNHDEARVMAQAAPQLVQAVTDIGAWRVVMLNTA
VQGATHGFLEDDQLALLETALEEAGGRHCLVCLHHQPVDIGCAWIAPIGLRNALALFDIV
EAYPQVRALLWGHVHQEWDELREGRRLLATPSTCIQFAARSEDFKVSEEQPGYRWLRLHA
DGRLETGVERATDFEVKLDFDSPGY
>A0A5B8RDN3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured organism|TrEMBL
MESTNDDGAHGLAFAHLSDPHLTSLRALRRRELIGKRLLGYLSWRRGRRHAHCDGILAAL
QRALASHPDEEIAVTGDLTHLGTPDEYREARDWLAALGPGPQVTVVPGNHDLYVPVRWQD
TLAEWAAHMCGDGDERPRFPFERRRGPVSFIGVNTAYPSAPLLATGRIDGDQLDGIGRAL
ARAGEAGRFRVVLMHHPPQPDAVSRRKSLVAAERFRALVRRHGAELVLHGHAHRRLRGEI
DGPRGPVPVLGAPSASQRTHDPARNAAYHRCVVTPTPTGWRLGVTVHAYDAETGDFVPRA
DAGGTLEIPRQSA
>A0A7J5WVP6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gordonia sp. YY1|TrEMBL
MFVVAHISDLHFNGTRFNRSRIQSTLSYINARAAGIDALLVTGDIADEGVPSEYREAFGV
LQSPLPMLITAGNHDVREPFSATLLGAETSGPINHARRVGDVLFLMCDSSIPGRNDGYID
DQTLTWMSARLEAEDPQTPVFIAFHHPPVELHMPFMDSIRQTGEERLVPLVERHPNIVAF
LCGHAHTPAVTRFADRPLCVAPGVASTLNLPFEGNEVVNRGQPPGIAFHIYDKGRLVTHY
RSVMF
>A0A2T3VS39|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium punjabense|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKVRQDAFDLIV
ATGDLAQDHTLQAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSAVLDRYPKVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>V1D7E0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella decolorationis S12|TrEMBL
MVANNGWFASLKNWVFNVLKEAVSYSIADESVRIVQVTDPHLFADPEAQLLGVNTSKSLA
AVLNTIRAVNYPAHLMLATGDLSQDYSPESYRHFVTAVAPLNLPCHYLPGNHDDPRIMFL
HMQGERVFGQQRVLIGKWQILMLDSTVRGKPGGHMGESQFELIEQAVAAHPEHHTLLVMH
HNPILVNCAWLDQHCMDNGTEFLRRVAQYPQIKALLWGHVHQQLDTHYDGPHGMLQLMAT
PSTCIQFKPQSPYFALDVLQPGYRLLELKADGSISTNVYRVPGNLFSPDKDSSGY
>A0A2X4UE89|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus haemolyticus|TrEMBL
MKNTFVYQVEKPVIKLLQITDPHLFKDESAELLGINTQSSFAQVLKEIQQENNEFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQSPMDEAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTKVKRIQQAEFLPNMQEEGY
>A0A151N278|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alligator mississippiensis|TrEMBL
MLNLRRGSPGASPGTSPRNSPRNSPVLFRKLLMNQSIRLQRRFTVAHPLCFDIENGLASA
RSPLDPQASPSAGLVLQGPFPHSQRRESFLYRSDSDYDLSPKSMSRNPSIASDLHGEDMI
VTPFAQVLASLRTVRSNVAALTHLQDRVTNKRTTSNSPAPTCKPSLSVKALLL
>A0A7K0BYN7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinomadura macrotermitis|TrEMBL
MTAEISRRRVLKSAALGAGIASSGLVAFPARPAEAAAAPRGPVAGTTLDRTYVLGRPGAG
GYRKVAAAPGEPHLLRRDLGGAAAPGRAARRRGVLAFGQLTDVHVIDAQSPARVEFLDRF
KDGLAVLPVEGAYRPQELLTTQVAEAMVQAINKVGRGPATGLPLAFTINTGDAADNVQYN
ELRWIIDLLDGGRITPDSGDPRRYEGVMDWGNYDDRFWHPEGPPPGAAADVAIAEHGFPR
VKGLLDAARKPFDATGLKSPWLAVFGNHDGLMQGNLPPNPLVQALATGGIKIGAPGSDAE
AARLARMLRGADGRELVRLSKQGGLFRQVTPDARRRMVSRAEVVREHFTTTAALRGHGFT
QRNLREGTAYYAFDQGVVRGLVLDTVNPSGYSEGSLDRAQLAWLEAELKAGSRRYTDAKG
KKAAHNVKDRLFVLFSHHPIASLENPLGGGRVLGDEVKALLLRYPNVVLWVNGHTHRNEV
IPHARTGGGGFWEVNTAAHIDFPQQSRIVELADNGDGTLSVFATIIDSAGPASFGGRLGD
PVHLAALSRELAGNDWQDDGDARRGKPEDRNVELLVPAPF
>Q8EAK1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella oneidensis (strain MR-1)|TrEMBL
MLKEAISYSIADESVRIVQVTDPHLFADPEAQLLGVNTSKSLAAVLNTIRAVNYPAHLLL
ATGDLSQDYSPESYRQFVSAVAPLNLPCHYLPGNHDDPRIMFLHMQGERVFGQQRILVGK
WQILMLDSTVRGKPGGHMGEGQFELIEQAIAAHPEHHTLLVMHHNPILVNCAWLDQHCMD
NGAEFLRRVAQYPQVKALLWGHVHQQLDTYYDGPHRALQLMATPSTCIQFKPQSPYFALD
GLQPGYRLLELKADGSISTNVYRVPGNLFSPDKDSSGY
>A0A663M1Q3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Athene cunicularia|TrEMBL
MASGGNGSGSSLLGDFIWQPGACSVNIVVGFEEQSFDVENGPSPGRSPLDPQAGSSSGLV
LHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSSLPSEQHGDDLIVTPFAQVLASLRSV
RNNFTLLTNLHGTSNKRSPATSQPPVSRVNLQGSEDIQANHDSIATDKNCFPLRPTCGCH
MKMLHVLLPSGACHSPGPSCRPWGERLRCHRDPPPALTPSSCSSETGWALWGQPRRLFAS
VAG
>A0A1K2FXQ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces sp. F-1|TrEMBL
MEPTAGPGQLLAISDLHISYPENRRLVEELRGGEEDWLIVAGDIAETVEDIRWTLATLAG
RFRKVLWAPGNHDLWTHPKDTVTLRGVARYEHLVEVCRELGVVTPEDPYPVWHGAGGPAV
VAPLFLGYDYSFLPAGCTTKAEGLAYAESTGIVCNDEYLLHPDPYPTREAWCRDRVARTE
ERLAGLPADLPTVLANHYPLDRHPTEVLWHPEFAMWCGTTLTADWHRRFRVATMVYGHLH
IPRTTWHDGVRFTEVSVGYPREWRKRPAAPGKPRRILPMEDETGDRGAAPGVGRGRGGAP
>A0A3F2V6L1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ketobacter sp|TrEMBL
MRVVQLSDSHLFKSPEGKLLGLNTEHSLSMVMDLIAAEQRHIDLVLATGDLSQDGSSESY
NRFHQHMEAFACPVYWLPGNHDLTDMMANHQVAKRMSPCVIPLNGWHIIMLDSTIRGKVP
GNFADSELVFLQQALQQSAGNNVLIALHHQPVPVGSEWLDQQIVGNAAEFFRIVDQFHNV
RNIIWGHVHQAYEGERKGVKLMSVPSTCVQFRPKSFDFAVDRENPGYRWLDLHADGRIET
GVSRVTGVDFVVDYSVRGY
>A0A2Z4AKB0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Moanabacter tarae|TrEMBL
MPLHHGEPAFNCYTDGGIQWLTIDNSTYEVTEGQLRAVEDSLKNSIPTVLLMHVPLSLPT
LRNDTQARFQTPLASGNILMGDPDWDMESREKWGTGDDLESTLEFVNVVTSARNLIAVFC
GHIHFPHTDAMGPTAVQYVGAPGFEKAMRVVDFLPM
>A0A4R0FPX4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. ANC 4173|TrEMBL
MTLKQPHDQQQSWTIIQISDTHLMNQDDLEFVHMNPEQSFHRVIAQIQHEYPHAHALIHT
GDLAQIPVSETYQRYLDFMQTTGLQYYQVPGNHDSEEFFPFHDQQNKVHAIPIGNWCLVL
LNSAVKGKIDGWIDTEQLKQLDQILSLHAEQSILIACHHHPFEMQSRWIDQHILKNTEHL
TDILAKHSNVKLVLCGHVHQASENQWHGIHFLSTPSTCVQFKPHSDDFALDDEAPGYRVV
QLKANGQFTTQVHRTQPIQKKINIEITGY
>A0A7X5BA22|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. V29_P1S30P107|TrEMBL
MNVSPSLSPSDHIKLVQITDTHLFAPDDGCLLSVNTADSFRAIVQAIIEQQIPFDAILAT
GDISQDHSAESYQRFAAGIRDLQKLCFWLPGNHDYKPNMGSVMPSAQIQALEHVLLGKHW
QMVLLDSQVVGVPHGRLSDYQLGLLDEKLTQYPDRFTLVLLHHHPLLVGSAWLDQHTLKD
SDAFWHVVGQHRNVRAVLCGHVHQAMDCEYQGVKVMATPSTCVQFKPNSDDFALDLCSPG
WRELELHHDGEVSTQVKRLRKGAFVPDFTSSGY
>A0A855Y849|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. ARC270|TrEMBL
MDSLLTLPVANGSEIRILQITDTHLFAGKHESLLGVNTWSSYEAVVEAITAQQRDYDLII
ATGDLAQDHSVEAYQHFAEGISRLPRPCVWLPGNHDFQPAMVDTLAAAHINAHKQVLLGD
QWQIVLLDSQVPGVPHGMLSDYQLEWLDNALARFPQRHTLVLLHHHPLASGCTWLDQHSL
RNSHQLDAVLQRYPLARTLVCGHIHQELDLLWHGRRVLATPSTCVQFKPHCTSFAIDTVA
PGWRWFTLHPDGGVETEVNRLDTDAFRPDLDSEGY
>A0A6J0BG15|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Neodiprion lecontei|TrEMBL
MKNANTLAMNRAPRSSTRSVQSFQSFADVDREELDGNAGMPDTRRQTKPILYVYGPTESE
NPNTSIEDSDTWFTRLIPGICTRLAATCCQSRYVMEVKEPAIPIVIPVTYKGPQDLKSNL
LTSWSPSSTKIMLVFGRDDHQSEVLGSAAKKLGWSVTYSRSTDTALETFHSRGHDIVVID
HRGSRGIDSDSLCRLIRASGVNPNTVIVALVRKSFLINADQDQIMTIGLMGIGFNRTLLE
CSQENLLANELVNIHASELQPRLHLAAFHALYVAVDRCRDMVHVTNDRHVVQFANKASER
FLGYKPEELLGNKIMDIVSSDNFVLMDQHLRRGREWEGNMNCKRKSSKTITVNCRIVPFS
ASGRTPTHYIYVHDTTYLLENMAIGPGNTGTQQMPRGSVHSLRRGSFDVKSTGSETHRRS
SFTKIHNLPLEAPITRVIGILSTALNDMSTTSPELALQMYKAIELLKGTELYTPQLREDT
RGYDPVTEDLVGALLASPVYARDSRRSSNDSVSRIPTSKTLTNASAHRMSLKGYRPPQEI
HDMMEKSLDWDFDIFKLEVLSCGRPLVYLGMNLIGLYEGPATLGCDEKTFFNWLTLVEMH
YHADNSYHNSSHAADVLQATAKFMRSERLKMIFDPLDEVTALIAAAAHDIDHPGRSSQFL
CNANNKLAILYNDLAVLESHHAALTFKLTLADDRANIFKGLDRESYKVARQNVIDMILAT
EMTRHFEHLAKFVNVCSNRMAGDSQSEPVSEVIDMTVLLQPENITLVKRMMIKCADVSNP
TRPLKACIEWARRIAEEYFRQTDEEKQNGMPVVMPMFDRLTCSIPKSQIGFVDFIINDMV
EAWDTFVDMPELISHMRLNYDKWKEYQEQGISTLQDIEKLQTSPELQIPRRTT
>A0A5B7VTX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. MPC6|TrEMBL
MPRVPTLTTADPALLVQLSDSHLFAEAAGTLLGMNTRDSLQHVIELVRLQQPRIDLIIAS
GDISQDGTLESYQQFRDLTRQLDAPARWIPGNHDEPRIMAEAAVQSALLEPVVDIGNWRV
TLLDSAVPGSVPGYLEVEQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFSVLDRFPQVRAVLWGHVHQEIDRERNDVRLIASPSTCIQFEPGSDDFKVGDQAPGYR
WLRLMPDGELVTGVERVTGFEFQVDYGSNGY
>G3UZ46|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus musculus|TrEMBL
MNKAAAIVLSGDMKKGTCSQKRGTQLKKNQRGSIRVASFDVENGPSPGRSPLDPQAGSSS
GLVLHAAFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASL
RSVRNNFTLLTNLHGAPNKRSPAASQAPVSRVSLQVERNDV
>A0A7H8GEQ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. 43A|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEADGALLGMNTRESLQKVIELVLGQQPQIDLILAT
GDISQDGTLESYQQFRKMSAQIAAPARWIPGNHDEPMIMAQAAVQSTLLEPVVDIGNWRV
TMLDSAVPGSVPGYLQDDQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQARAVLWGHVHQEIDRERNGVRLMASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGRLETGVERVTDFAFTVDYGSEGY
>A0A665SXT3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Echeneis naucrates|TrEMBL
MAPLRFLFRVLDFSLLQSSYEAENGVSPGHTPLGSQSPGLTLNTSFSQGQRRESFLYRSD
SDYDMSPKTVSRNSSLASEGHTAEDFIVTPFAQVLASLRSVRSNFTILANVSTPTVKSVP
IIVVQKCATDVCCCLCKHSVYNTVYDSSS
>A0A3S9X5C7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microbacterium oxydans|TrEMBL
MSAGTGTPYVFGRHEPASHVLIHVSDPHFLAGGVRLGGRYDVEENFARTLEAIRAVHPHP
TAIVVTGDLADLGEPDAYRRLRAAVEPVAEELRAPVIWVAGNHDERPALREGLLDLTPTE
EPVTGVWNLDGLRLIALDTSVPGWHHGDLDDGQLAWLAEVLAEPAPHGTLLTMHHPPIPS
HLPLFDILELRHQDELADIVRGSDVRGILAGHLHYSSHGLFAGVPVSVASATCYTMNVAR
PSAEVNGMDAAQAFQIVHVYPDTITHTVVPVTEAPTGDYFSEAWLERMAKLSPEGRLEAF
SRKPGR
>A0A6M1ZMM0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chlamydiae bacterium|TrEMBL
MEPIRLAHLSDPHFASVTYSPRQFFSKRWLGNTNLILFRKKAYQTDHLKHIPELLETLDV
ETVFITGDVATTSRDEEFAKAAAFASKFKQPVHLVPGNHDCYTRGSDREKRFYRYFPALY
DRRSTSFNTKPFTNRKITRSR
>A0A6M1ZCU0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chlamydiae bacterium|TrEMBL
MHSSDQVRIAHISDLHFGRPTFNPLQFFSKRWLGNLNLLLTRQHQFDHTRLDTLLDLFDR
EGVTHVAITGDLSVTSRRREFHIAKEFVEKIRVAGMTPMVIPGNHDQYTKRAYQRQLFYR
FFPSKWDSEFPFDLSKDKLTGMALSEDLWFLALDTALATSLISSQGMFSESIEQSLEKAL
EAIPKSARIILLNHFPFFQHDPKIKQLLRAPALKSLLQRHRNVRLYMHGHTHRQTLADLA
TSNLPIISDSGATVHRSHGACHIITPGKDAVDIAVFLYEDQWTKKDAKNFRW
>A0A679JBS7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Variovorax paradoxus|TrEMBL
MSCLLQISDPHFGTEQPDVLRALEQLAAALAPGVVVLSGDITQRATAAQFAAARAFADRL
GRPVLAIPGNHDIPLFQLAARVFAPYGRYCRAFGDDLEPTFESREWLVATVNTTRWYRHE
DGAVSAEQIERVARRLAQASPSQVRVVVTHQPVMVTRGQDLGNRLHGREQAVARWCAAGA
DLILGGHIHLPFVRPLHDAFPGCAPTAWAVQAGTATSTRVRAGHPNSVNVVHADIAGGAD
GRRACRVERWDYVARDKAFGCAEVFGLSLASEAVQP
>A0A1T4TC15|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium toruni|TrEMBL
MQTYSLPQTNPESVVLLQITDTHLFANGSGSLLGVATKDSFHAVLAGVDIAARHFDAIVA
TGDISQDHTPYSYQRFADGISRWSQPCFWLPGNHDFQPTMQSILPSEQIKPQQQVLVGEH
WQMILLDSQVQGVPHGELNAAQLVLLDAALARYPDRHALILLHHHPLEAGSAWLDQHKLH
NNSGLWNVIDRYPQVKAILCGHIHQDLDRIYHGVRVLATPSTCIQFMPDSDDFALDHNNP
GWRYLELTKDGHIITSVHRISGDQFKPKLDAEGY
>A0A6P4IPD8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila kikkawai|TrEMBL
MIISSQPNLAGSATSTTPSPSTNPNSNPSSHTNPSAAAAHMGDESVPSNCNCNVGVDLVG
IGARQSPVPALEAAGRDSLMRPASDESELNVGTGTSGTSSSGGGNSHRHRKSSLALALTP
EDEPMDVYQRNLMDLKYPTVLPPNPQLKALLVFHKADSICEAVTAACQRHQLDVTLVKSK
EEALDTLQKSYATAQCYHLIIIDARSAKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFE
KDDVLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEV
VLITDDVLRIQYANRATERLLNMRLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTV
RRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRR
CSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLK
REGLYSPQMKEIRTDDPIATDLIGALLTVGPSVYSSRRSSNDSIIRTGSSTRTATIVPAK
MKANPIIMELLEESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAW
LAVMEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDMLVMDRMDEATALIAAAAHDVD
HPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARS
TIIDMILATEMTRHFEHLAKFVSVFGGEEPREQHSQTEEETSILMRRMLIKVADVSNPAR
PMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHA
WESFIDMPQLITYMQINYSQWKKYDEQGVNTLADIMAKQPPVGKMANSK
>A0A7Y7SQY0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. B9002|TrEMBL
MDSLLTLPAQDGSDIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIEVQQRQYDLII
ATGDLAQDHTVEAYQHFVAGINRLPKPCVWLPGNHDFQPAMVDTLADAGIKSDKHVLLGD
HWQLVLLDSQVFGVPHGMLSEYQLEWLHTALSKYPERHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLQHFPRARNLVCGHIHQELDLDWHGRRVMASPSTCVQFKPHCTNFTIDTLA
PGWRWFTLQPDGALHTEVNRLQSDMFRPDLDSEGY
>A0A5E4IWX2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKLRKELIFFTLIITSFAGALGTAQPSSEPIDVNASAVPDHITLSWTDNPMTTQTVTWRT
DGTVQTGVVQYGMDRELKDNAARSVAAQVSRLKTELGDENIFTAKLTNLEAGTRYYYKVG
DHKSNWSPVYSFRTEENDTNRFQFLIFGDTQSGNDKKPDYSLWQSTVQNAYKANPDANFF
VLVGDAAQAGRSAIHWDYWFAACKGVIDSISYMPVEGNTETRDINKTHGEATLYINQFKV
PHNGPYNNSEAYSYDYGNVHFVVLDSQLHEKPEINPNLLNEQKAWLEKDLSQTNKEWKVV
FWHKPPYSIRSYHTYNAIKAAFTPIIDKYHVDMVFNGHDHAYCRTYPINNDSIVSSPALG
TVYIIAGRSGAKYLNDIEPKVWSANFFDPQDMPNYLVVDVNGSRMEIKNCKMDGTLVDDY
IIDKTGSDMQRTAVPPKYNNPKLVVNGVLLNKPMMPTTPSQINSKWYFPIKPVVAFLGGS
ESVSGENETLSLIVNEYDSSKIWSDEEVHTVILTNASTKATIDEARITLPDSVVIDSGKN
FLISADDMNVLFGFTWKYDSERNILSLINPSEFGE
>A0A5E4I747|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MRIVHISDIHCTQGTDFNEKVYEKATKLVNSLNADFVFISGDLTTDGLLSEYELAQKKIK
EISSKVFVVPGNHDERNLGFKLFPEFFGETDFIHSLKDVTLIGLASSEPDKDDGRLGRGR
YRKIVDCIAPNKLTIVGFHHHLVPVPGSGRETNIIEDAGETLDLILRKEVPLVLMGHRHV
PWAVKIHKTLLVNAGTFSCNRTRAHHGYTFNVIDIEDKIVTVSIVDIRKEQTRKMVEFNL
KDGCCTNRYYDSYTGT
>A0A452RWG3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ursus americanus|TrEMBL
MVSRLRVASYPSLGATAGPRANFLFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNE
VEIPSPTMKDREKQPPMSQITGVKKLRHSSSLNDSSIPRFGVKTDQEELLAQELENLNKW
GLNIFCVSECAGGRSLSCIMYTIFQERDLLKKFRIPVDTMVTYMLTLEDHYHPDVAYHNS
LHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALM
YNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLAD
LKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQ
QGDRERERGMEISPMCDKHTASVEKSQVQFCRSCGRCDDSSSCAYLT
>A0A452RWC3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ursus americanus|TrEMBL
MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAEPERS
PHRPIERADAVDTGDRPGLRTSRMSWPSSFHGTGTGSGGASGGSCRRFEAENGPTPSPGR
SPLDSQASPGLVLHAGAAASQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
FAQVLASLRSVRSNFSLLTNVPIPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLGEPSQQPP
PPGPQFQPMSQITGVKKLRHSSSLNDSSIPRFGVKTDQEELLAQELENLNKWGLNIFCVS
ECAGGRSLSCIMYTIFQERDLLKKFRIPVDTMVTYMLTLEDHYHPDVAYHNSLHAADVLQ
STHVLLATPALDAGPAGLEVGPALPHPALLTRGPCPSLTTCLGLGADSELALMYNDESVL
ENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVET
KKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERE
RGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSA
IRQSPSPPPEEEPRGPGHPPPPDKFQFELTLEEEEEEEVSTAPGRPSPAEELSDVDGQAV
PTAVKGEEPRFTQQADSADSVATGQDESVSPDASVEAGGRSSPLALSAESPPLPALRTPP
PPEEAPGLPGLPSMAAEVGAQKEHQAAKRACSACTGTSGEDPPPLPAPGGWGSAGGPT
>A0A452RWB3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ursus americanus|TrEMBL
MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAEPERS
PHRPIERADAVDTGDRPGLRTSRMSWPSSFHGTGTGSGGASGGSCRRFEAENGPTPSPGR
SPLDSQASPGLVLHAGAAASQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
FAQVLASLRSVRSNFSLLTNVPIPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
PSPTMKDREKQPAPRQRPSQQPPPPGPQFQPMSQITGVKKLRHSSSLNDSSIPRFGVKTD
QEELLAQELENLNKWGLNIFCVSECAGGRSLSCIMYTIFQERDLLKKFRIPVDTMVTYML
TLEDHYHPDVAYHNSLHAADVLQSTHVLLATPALDAGPAGLEVGPALPHPALLTRGPCPS
LTTCLGLGADSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVID
MVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPL
ELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWAD
LVHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEEPRGPGHPPPPDKFQFELTLEEEEEE
EVSTAPGAFEVQDLSMAQRPSPAEELSDVDGQAVPTAVKGEEPRFTQQADSADSVATGQD
ESVSPDASVEAGGRSSPLALSAESPPLPALRTPPPPEEAPGLPGLPSMAAEVGAQKEHQA
AKRACSACTGTSGEDPPPLPAPGGWGSAGGPT
>A0A366XEQ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrionales bacterium C3R12|TrEMBL
MKLSSSSESALGSIKLLQITDTHLFAPADGSLLSVNTFDSFQAVVRDIQAKAFKFDAILA
TGDISQDHSQESYQKFESGIECLQKPCFWLPGNHDYKPNMSSVLPSPQIQCVEHVLLGER
WQMIMLDSQVVGVPHGRLSDQQLALLDEQLTLHSDRHTLVLLHHHPILVGSEWLDQHTLK
DAEQFWNVVDQHQNVRGVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSNDFALDSQSP
GWRELELHLDGSIETQVNRLSDGRFLPDFNSDGY
>A0A8C2KLW2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyprinus carpio|TrEMBL
MLNRELTQLSETSRSGNQVSEFIASTILQKQHDVEILSAACKEEKKRRPMSQISGVRKLS
PSPSLPPTCIPRFGVNTQHESLLAEELDDINRWGIDIFKIAEYSGKRPLTVIMYTIFQER
DLLKTFKIPSDTFLTFLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEDVFTDLE
IMAALFASAIHDVDHPGFTNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIF
CNLSKKQRQSLRQMTIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQV
LQNMVHCADLSNPTKPLELYRQWTDRIMVELFRQGDRERVKSNVITIFLKLYIGVYRL
>A0A8C1EYN2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyprinus carpio|TrEMBL
MLNRELTHLSEMSRSGNQVSEFISNTFLDKQHDVEMPSPQTQKEKEKKKKPMCQISGVKK
LMHSTSLTNSNIPRFGVKTDTEDSLAKELEDINKWGLNVFKVTEFSGNRPLTVMMHTIFQ
ERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHSNIHAADVTQSTHVLLSTPALEAVFTD
LEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCD
IFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTNRIQVLQNMVHCAD
LSNPTKPLQLYKQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVAIEVLELC
FYRLPYYESKIKQLIVR
>A0A8C1DU44|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyprinus carpio|TrEMBL
MTRFYCTSLATNLGAHMSFWEMYSKRRENVQLSVQTLFLCKENLYFFFVLNYCFCTVVVF
LFVCFITPFSLFLCSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDS
DYDLSPKSMSRNSSIASDMNNHLPRPGLVSRRSEPVISGNHGDDLIVTPFAQVLASLRTV
RNNFAALTNLQQDRTSNKRSPMCNQPPLSKASFTGEILIPFQKLDFKTLNCVFHSVVLFS
LALHVIFHSFYVKC
>A0A5Y3V0Q7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQHEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCTNFTLDTIA
PGWRTLELQANGSLETEVHRLQDTRFRPDTASEGY
>A0A8F8CKV6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lelliottia amnigena|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAENRHCDLIA
ATGDLAQDQSAAAYQHFATGIASFSVPCVWLPGNHDFQPAMYSTLHDAGISPAKRVFVGE
HWQILLLDTQVFGVPHGELSDFQLEWLENKLAAAPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLSKYPHVNNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLQSATFRPDTASEGY
>A0A0H3FJS5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella aerogenes (strain ATCC 13048 / DSM 30053 / CCUG 1429 / JCM 1235 / KCTC 2190 / NBRC 13534 / NCIMB 10102 / NCTC 10006 / CDC 819-56)|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLHDAGISPAKRVLLGD
HWQILLLDSQVFGVPHGELSDFQLEWLEHQLNAEPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDHILSNYPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGVLTTEVCRLSGAEFHPDIASEGY
>A0A1T5I3C2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium piscicola|TrEMBL
MQTYSLPQTNPESVVLLQITDTHLFANGSGSLLGVATKESFHAVLAGVDIAARHFDAIVA
TGDISQDHTPYSYQRFADGISRWSQPCFWLPGNHDFQPTMQSILPSEQIKPQQQVLVGDY
WQMILLDSQVQGVPHGELSAEQLLLLENALTRYPERHALILLHHHPLEAGSAWLDQHQLH
NNSGLWHVIDRHPQVKAVLCGHIHQDLDRMYHDVRVLATPSTCIQFMPDSDDFALDHNNP
GWRYLELTKDGRIITSVHRISGDQFKPKLDAAGY
>A0A402DGG9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcystis aeruginosa NIES-4285|TrEMBL
MQRRKFLLISGSLGGFSLAACAHQILQPVTSKNPPESAVKQAQKAKKVKIIVISDLNSQY
GSTTYDPEIDRAIPLIINHKPDLVLCGGDMVAGQKSSLTEAAINAMWSAFDHHIAAPLRA
AKIPFGFTIGNHDASGALSAGKFIYAKERKLAQDYWQNPQHNTSLNFIDKTGFPFYYTFT
QNGIFYLVWDASTHLISRKQLNWAAKNLSSSDAKNARMRLVIGHLPLYGIAVGRNRPGDY
LADAEQLRAFLEAHQVHTYISGHAHAYYPGKRGQLQLLHAGALGSGPRRLLKSEQAPRKT
LTIVDINPHQQETVYTTYDMKTQEAIDITSLPPLIMAPNGQVLRRDIPSVN
>A0A839BUE2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. RHBSTW-00318|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFVGE
HWQILLLDSQVFGVPHGELSDFQLDWLETKLSAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVQNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHPDGLLTTEVCRLTGAKFRPDTASEGY
>A0A7C9GK54|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus khanii|TrEMBL
MESQFKLPVVEGTTAKILQITDTHLFAGKEETLLGINTYRSYHAVLDAILKQNADIDLIV
ATGDLAQDQSLEAYRHFAAGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGE
HWQLLMLDSQVAGVPHGELSEYQLEWMKKCLDIYPERYTVILLHHHPLPSGCIWLDQHSL
RNSHILAEYLQGYSRVKAMLCGHIHQEVDMDWNGIRMMATPSTSVQFKPHCTNFTLDTVA
PGWRYLELSISDRGEFGLTTQVHRLESNEFCPDLDSDGY
>A0A8G2CZR7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas dhakensis|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRIASQVWRLPVGQFVPDPNATGY
>A0A5E6Z0K1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPNVSTLTTEDPVLLVQLSDSHLFAEADGSLLGLKTAQSLQQVIDLVQAEQPHIDGLLAT
GDLTQDGSVEAYQRFRTLTAPLAPFGRWIPGNHDQVAQMREAAVQSRLLEPVVDIGNWRI
TLLNSAVPHSTPGYLEDDQLQLLAQSLSEAPDRHHLVCLHHHPVSVGCPWLEPIGLRNAK
EFWSVMDRYPQARAVLWGHVHQAFDQQRNDVRLLATPSTCIQFAVGSPDFKVSGEAPGYR
WLRLQPDGTLQTGVSRLADFTFEPDYSANNY
>A0A5E7AKK3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPRVSTLTTADPALLVQLSDSHLFAEAAGTLLGMNTRDSLKHVIELVRLQQPRIDLIVAS
GDISQDGTLESYQQFRDLTRQLDAPARWIPGNHDEPRVMAEAAVQSALLEPVVDVGNWRV
TLLDSAVPGSVPGYLEVEQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFSVLDRFPQVRAVLWGHVHQEMDRERNGVRLIASPSTCIQFEPGSEDFKVGDQAPGYR
WLRLLPDGELETGVERVTGFDFQVDYGSDGY
>K5UMD5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. HENC-03|TrEMBL
MLSVRTADSFAAVIQEVLHRQVQFEYVLATGDISQDHSAESYQRFAEGIAPLKKDCFWLP
GNHDYKPNMGSVLPSPQIQAVEHLMLGEHWHLILLDSQVVGVPHGRLSDQQLSLLEEKLA
ENPQRHTLVLLHHHPLLVGSAWLDQHTLKDAEAFWQVVDRFENVKGILCGHVHQDMNVLY
NGIRVMATPSTCVQFKPNSDDFALDTESPGWRELELHSNGDITTEVNRLPDGQFQPDFTS
NGY
>A0A7Z3ALQ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. ADAK18|TrEMBL
MPSVSTLNPDAAALLVQLSDSHLFAEADGTLLGMNTRDSLQRVIDLVLARQPQIDLLLAT
GDLSQDGTLESYQAFRDATRQIPAPARWIPGNHDEPQIMAHAAINSALLEPVVDVGNWRI
TLLDSAVPGSVPGYLQDRQLQLLAQSLSEAPTRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVKAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFNVSEEAPGYR
WLRLHADGRLETGVERVEGFAFQVDYGSNGY
>A0A6S7E7I6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter anxifer|TrEMBL
MARIHSLTRRDDAPAMLVQLTDSHLFGEPETSMLGVNTDASLRAVLRQIEADGKHPDLLL
ATGDMSQDGEAEAYRRLARVLSEAPALAQANIRCLPGNHDLPGVMRQELPQWSAPVTDVG
AWRVVSLDTTVPGSNAGHLPANQLDLLEAALAEAPGRHTLIAMHHNPMQIDSHWHDSMMI
DNPQALFKLLTHWPQVRVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNMA
PGYRWIKLYQDGSMATGVRRVQDALWHGAKTASDNAEAA
>A0A6J5EMY4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia solisilvae|TrEMBL
MLLAQISDLHIKRPGALAYQRVDTAAYLSRCVAALNALVPRPDAIVVTGDLVDQGDVDQY
EHLKALLAPLQIPYYLLVGNHDERAALRTVFAERQELLGGGEFVQYAVDVGPLRLLALDS
MVPGASGGTLCAARLAWLAAQLDAARGKPVIVALHHPPFVSGIGHMDRVRLDPAAAREFE
ALIARHPNVERVICGHVHRPMFARFGGTIASAVPAPAHQVALDLRDDAPSVFRMEAPAFA
LHRYDAATGVVTHHAYVDQGDGPYPFHAPAGALID
>A0A6J5DVG3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia solisilvae|TrEMBL
MQTTLRHLKRRDFLKLAAVGGAAFASALPGFTYGRDRDFYFVQLSDSHWGFEGPAVNPDA
KGTLPKAIAAVNALPVKPDFVIFTGDLTHTTDDPMLRRERMQQFETIVAQLNVKPLYLMP
GEHDASLDAGAAYKERFGATHYTFDHKGVHFITLDNVSDPAGRVGAEQIAWLAADIDRQP
QDARIVVFTHRPLFDLAPQWDWATRDGAQVIDVLTRRQNVTVFYGHIHQEHHTMTGNIAH
HAARSLMFPLPAPGSQEKRLPVPWDAAAPYRGLGWRQVEVNGQPRAFALNEMPVRNPSAT
>A0A2S5CDD3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lelliottia sp. 7254-16|TrEMBL
MESLLNLTVAGGTPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIRVENRDCDLIV
ATGDLAQDQSAAAYQHFATGIASFSVPTVWLPGNHDFQPAMYSALQEAGISPAKRVFVGE
HWQILLLDTQVFGVPHGELSDFQLEWLETKLSDVPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKYPNVNNLICGHIHQEQDLDWNGRRLLATPSTCVQFKPHCDNFTLDTIA
PGWRWLELHADGSLSTEVCRLEGAKFRPDTASEGY
>A0A8F8BPI4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter hormaechei subsp. steigerwaltii|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEKRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGD
QWQILLLDSQVFGVPHGELSDYQLDWLETKLAAEPNRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDGVLAKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLTGAQFRPDTASEGY
>A0A545T779|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aliikangiella marina|TrEMBL
MVDKVEKIPHEIQPSRLDVVRFAQITDCHIFEDPQGCLLGLNTRDSFEAVRDRVLREEWR
PDGILATGDLSQDASPESYQYLADEFKATNIPTFWCPGNHDNPETMELYLSNSRVFAANQ
ILIGHWQVILLDSSVKGKVHGELADEQLEFLEKALKRYPDRHALVSLHHQPVDIGSHWLD
QIGLKNAKTFNRIIEKYKQVKGVLWGHIHQEYQKSVNGIRYIATPSSCVQFKPGSEDFSA
GVEAPGYRYLNLYSDGRIESIVHRIDNIEFTVDYSIKGY
>A0A4D6P0Z3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000189|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A427KCN1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia sp. 198|TrEMBL
MDSLLKLPVANGRARILQITDTHLFAGKHETLLGVNTWASFDAVLQAISACEEPFDLIVA
TGDLAQDHSAEAYQHFAEGIARLPAPCVWLPGNHDFQPAMFNTLAEAKIADEKHVLLGDR
WQIVLLDSQVFGVPHGELSDYQLEWLDTALAKAPERHTLVLLHHHPLPSGCTWLDQHSLR
NSHMLEAVLQRYPLASTLLCGHIHQDLDLNWNGRRLLATPSTCVQFRPHCTNFTIDSEAP
GWRWLDLYTDGRVETRVERLTTRAFSPDPDSEGY
>A0A7I8I2U3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas caviae|TrEMBL
METELPQAPDGSVRLLQITDTHLFASAEGRLLAVPTAQSLAAVLERVQANEHPFELILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHHGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRVASQVWRLPLGQFVPDPNATGY
>I6DRG9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella boydii 4444-74|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7H8UE95|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAENRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFVGE
QWQILLLDSQVFGVPHGELSDYQLDWLETKLAAEPDRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLVKFPRLKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLAGAQFRPDTASEGY
>A0A6F9ZM53|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacteroidaceae bacterium|TrEMBL
MKIQYASDLHLEFHENSRWLKENPLAAAGDVLILAGDIGYLGDDNYVHHPFWDWCAESFR
QTIVIPGNHELYKSFDINDLHEGWQQEIRPNVKTCYNCVIQLAPNIDLIASTLWAKIHPY
DEYQTERGVTDFHRIRNGQFRLSAQRFNQEHKRCREFIERSVGQSNAEHIIVATHHVPSF
ELMADEFKGSPINGAFTSELGDFIANSRIEYWIYGHSHRNINKTIGNTRCICNQLGYTFH
GEQADFRRDAVIEINDNEFQI
>A0A6F9ZF36|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacteroidaceae bacterium|TrEMBL
MMLIKLFLFFLTLLIVPDMYIYKAYIHRVSPKWIHWAYWLPSLFLLLGMTLVFSIHEPRP
ESMQRLSNFLLIFLCFVVPKALFVIVILFMKLLYIISGKKLYGGYIAGGLALASLAYVVY
GATEGKQHFQIRQVTIGSDELPSGFDGYRIVQISDIHSGSWTGNGSALQKAVNLINKQNA
DLVVVTGDLVNNVATELDEFIPILKQIEGKDGVYSVLGNHDYSPYIKWETKEAQEANLDS
LKSKQAAMGWKMLNNDHVILHHHGDSIALAGVENSGNPPFPNYGDLPKALKGTEGMYKIL
MSHDPTHWHREVLPESDVQLMLSGHTHEMQFSLFGFSPSNFVYSEHNGLYQEGKQSLFVN
IGLGYLMFPMRLGAWPEITVITLHKNI
>A0A1I7JJI9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus koppenhoeferi|TrEMBL
MESLLEVPVAKGATTRILQITDTHLFANKGDSLLGVNTYNSYHAVLDMILEQNLDIDLIV
ATGDLVQDQTISAYQHFAEGIARLSAPCVWLPGNHDYQPAMVDTLAAAGISPSKQIFIGQ
HWQLIMLDSQVQGVPHGELTDYQLEWMKKCLDEHCDRHAIVMLHHHPVPSGCTWLDQHSL
RNAPELSELLKGQTQVKAILCGHIHQEIDDMWNGIRVLATPSTCVQFKPHCTNFMLDTVA
PGCRYLELSVNGNQDVRLQTQVHRLKSNEFCPDLDSDGY
>A0A844L4R2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alcanivorax sp. VBW004|TrEMBL
MTQQLQPLRVVQLSDCHLFADPQGKLLGLNTQFSLDKVLELIRKEQPNPDLILATGDLSQ
DASYESYERLDRALSGFDVPVYWLEGNHDKPAPMLQALEAHREKMSPCVLNVGNWTIVML
DSTIPGEVPGDLFDEDLKFLDTALRDATGEHLMVCLHHHPVPMECTWLDTQVVGSADQFF
QVIDRHERMRAIIWGHVHQEYDAHRNGVRMMAVPSTCVQFKPKSEDFAVDDANPGYRWLD
LHPDGQIDTGVSRVEGITFEVDFTVKGY
>A0A6M1ZH68|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Anoxychlamydiales bacterium|TrEMBL
MQIFAISDPHLSLSTPDKTMQDFGDTWKDYQEKIKINWEKNITANDLVLIPGDISWAIKL
KDALIDLEWIHDLPGKKVIIRGNHDYWWPSASKLKEALPPSISFIQNNALSFGDVSIAGS
RLWDTTEYNFNDYINFVFNPKQRKDIQEDIQEDLSERIFTREIERLKLSLEALDRNAKTK
IVMTHYPPISADLKDSKVSKLLEKYKVDICIFGHLHNLKREKKMFGEKNNIKYILTSADY
INFTPVKIL
>A0A6M1Z3Z3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Anoxychlamydiales bacterium|TrEMBL
MITIAHLSDLHFSNISIFPLSLKRFIGTTNLLITRKRSYIDTHLFKLPDLLKSLNVNNIF
ITGDLSSTSLKKEFEKAKKFIDSFDENMKFFIIPGNHDTYTRQANKQSYFQNILKSNNII
DSKQKKIHLFDLSKKWVYIGLDTTLVTPLFSATGLFSTEMEKDLIDILEKIPKDKNIIIS
NHFPLFHKAPKRKLLKRRDDLLKVIKKYPNIKLYLHGHTHKPSITKEENLPYMICSGCSS
HKKNASFSILKIEDDKCNIYCYILQDNNWQKDKVEELNFS
>A0A2M8GW13|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. HA2012|TrEMBL
MLKSSTVDIREPGVLEQNTNTEDENSQSITLLQITDTHLFSASDGCLLSVNTLDSFHAVV
EEITHRHTAFDAIIATGDISQDHSKQSYQRFEQGIRRLEKPCYWLPGNHDYKPEMHGILP
SAQIRTDTHILLGDHWQVILLDSQVEGVPHGNLSEEQLTYLEQVLSDYPQRHTLVLLHHH
SVLVGSLWLDQHTLYEAEKFWERIEKYNNVRAVLCGHVHQEYDAIHAGVRVMATPSTCVQ
FKPDSTDFALDPISPGWRILRLFADGRLETQVHRLDDGRFHPDFSAGGY
>A0A6L2ZPR4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Regiella insecticola|TrEMBL
MKKGAYLENLFKLPMPANETEIRILQLTDIHLFADKKKTLLGINTADSYSAVLEAIATQK
QRFDLIITTGDLAQEPAITSYQYFARGMAELLPTPCVWLPGNHDDQRIMADVLFDAGITA
TKQVTIGDNWQILLLDSQVSEQPYGHLNDHQLLWMEQCLQMFPQRYTLVALHHPPLACGC
RWLDQNNLRNASMLAEIVLRYPRVTTLLCGHIHQEIDLNWCGKRLLATPSTCIQFKPDHA
TFTLDNVAPGWRCINLQPDGTVKTQVKRLANGLFYPDINANGY
>A0A644U3V6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MTAPLRFAVLTDLHFVPAGQRLYGFDPRAVLRRALAFLTTLPQVDFLVIAGDLTDRAEEA
AYASLRAELAALPVPVILMLGNHDARAPFRAVFPAAPRDANGFVQGLHVFAQASLITLDT
LCEAEEGHHGRLCAARLAFLEQALRAAPADRPVLLFQHHPPMDLAIPPMDAIRLRDAEAE
LAAFARAGRRPDYLFMGHVHRPIAGLWHGIPFHVQRALMHQVHHAFDRPGRILGATEAPD
LAWVSVAEGQVLIHDCSFAYDGPVFDLESAEAAAVATPQGLGRF
>A0A495AHF3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. R1(2018)|TrEMBL
MESLLNLPVAGGGRIRILQITDTHLFSGKNETLLGINTWESYQAVLAAILADRRHCDLIV
ATGDLAQDHSAQAYQHFAEGIARIAAPCVWLPGNHDFQPAMYSALQEAGISASKLVHIGD
SWQVVLLDSQVFGVPHGELSEYQLEWLERKLAAAPDRHTLLLLHHHPLPAGCSWLDQHSL
RNAQELDNVLVNYPQVKTLLCGHIHQELDLDWNGRRMLATPSTCVQFKPHCANFTLDTIE
PGWRWLELHPDGAVTTEVCRLKGAVFNPDTASEGY
>A0A644T842|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MHLKYIFFIQLLIFSINGNSQFIHQRQVSGANPWTSAPEISGDNYRFIVAGDITGGEEPG
VLAEAVHRINELSPDFVITVGDLIDGYTTDSLRAERQWDDFLKVIGNLEMPFFFTAGNHD
ITNPMLEDIWNRRFGSLWYSFKVGSSLFFVINPAGIANKGFDAGQLEYFKSRLENHNAGA
PVFIFMHYPAKEMADNDHFVEFSRLLMNYNAYWFCGHEHRYVYEKFNGQPHIMLAGLATG
GPGIRGHKLGEYHNLMQISVRGSEVRIANLDLAGLLPVDAVNPSTIKQVDVLRRGSWAEA
EVVYSTDRMVSSVFTRMLLKNEGEFPLHVSGSFMSEKNISINPVRIDTLIQPGETSLIPV
EFSAPEKFDLAGLNGITFNSTAEFYQPGAALMTTHELIVLSDYLRICHYSVDPQVSFTDT
EVPFEIEEDWDWKGNHDASFSLETTHDEKHIHISVKITDDRWVMSDQRAHDKLLVYFSPE
TTAKPQQAFQFQFNAGEGSARVFSASGRKIKFRSSAEINGDQMYINLSVPAGMVKTGYFR
LNLIYTDVDDPSGTDHTMLNWRPWETAGSWNKGAGIFLIK
>E1J0V7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli MS 124-1|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A660G8J2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pasteurii|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIRASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQILLMDSQVFGVPHGELSDFQLEWLEQKLAEVPERYTLLLLHHHPMPSGCSWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLDLHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A4W4EEI2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Electrophorus electricus|TrEMBL
SHEECACSDCSWFKRMLNRELSHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTLRERE
KPMCHISGVKKLTHSSSLTSAALPRFGIKTEHEDALARELDDLNKWGLNIFRVAEFSNNR
PLSCIMFAIFQERDLLKTFRIPVDTFITYVMTLEDHYHANVAYHNSLHAADVTQSTHVLL
STPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAV
GFKLLHEENCDIFLNLSKRQRQSLRKLVIDMVLATDMSKHMSLLADLKTMVETKKVTSSG
VLLLDHYTDRIQVLRNMVHCADLSNPTKPLAVYRQWTDRIMEEFFRQGDKERERGMEISP
MCDKHTASVEKSQVHTYKHRHTYTHTHTHTHTNCRFVMGAGALPSEGKSLIGRK
>A0A7R9N3Q6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Methanoperedenaceae archaeon GB50|TrEMBL
MTRIVHLSDIHVSESYFLADVAESVLQSVNEISPEIVVVTGDLTHNGSHQEFRDVKEYID
RIDCRNKLIIPGNHDSRNLGYLLFEDLFGARSQSHTFNGVTVVGVDSSEPDIDDGHIGRE
SYDWIAKNFETDDFKVFALHHHLIPVPMTGREVQIPVDSGDVLELLHRCGVNLVLCGHKH
VPWVWRLNEMFVVNAGSMSSKDIKARTTHCYNLIEVDRKDLQIYQVLPTGERRLIIDSNY
ESKNE
>A0A7R9R9J7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Methanoperedenaceae archaeon GB50|TrEMBL
MRLHKIILLLGILGVVVLQLQTGIASGSISVEDADAVRNFTLNTAPSDAINSTDVPQQET
FIDVFVNDADAARDFNLIGASDDALNSTDASEQETFIDVFVNDVDAMRDFDFSNSPPAGY
SVGQGAPDLATKNHFTDAYNRNGGADVLGSPTTEVHRAWGYLVQDFPGATGYAGGIIMYN
PYKNYAYYIHGAIWERYYDLGGPRATTDIEFELGPPVSDIEPYIHTHPPEVSSHGTQFRY
QNFEGGALEHNVDTGEVFEVHGAIFAKWRELGYADDELGLVTSDEREAAQSPIRTEGRVS
DFEGGHIHWHRTGGHAGKSYETHGAIDAVYCAEGGSGGDLGFPVSDEYVNPSGYPQSDFE
GGYITTTDGVNYYVYMNDDAEGPALEITSPEDGFHTDEYRIDISGTASDDSGILYGKVVI
ASSGFDNSDDRRTAKWDPETDKWETNIPLAHGDNVIRVFAVDNKHNPTEKTITVYCNPPD
FSFAHITDAHIDDDCETKWSWNNLKYEKYCESQEKFSSTLYEVNSKKPAFILDTGDCVEY
DDEELFKRYMETLDRYIDKDIKIYHTPGNHDRRNKFFETTDLSKYNAIVKPNNGPHTSLN
DGYGDYYFDEGGYRFIGLDSGHDWSVVDFLTPEGSGLEDDQYMRLLESDIKDHPKKIIFM
HHPVINEGDDGFGGIENRCPEKGGNDMCIGAFRCGLINYCIDHGVQLVLTGHTHKSYNVQ
ISNTRFIQTPSATKDTKWACPLVPDVVICKHGYRIIYIKSGKAYPQLYTTGAHSNVKGEL
ECPAHLHAYDSQGRHTGLNASGGVETGIPDSFYIGRYNYSDPNETETILLYNTTEEYRFE
IVANLTEEITGNESFNFTVEQQTDDTRTTIAHLRVPLTENTTATLPINLTTTAYTMEIDH
DGDGATDETEDPDFTVTNYAPTASINTPETGSIYNVSEPVEFNGTGRDPEDGILTNFSLV
WYSDINGVIGAGERFSTENLSAGAHRITLMVNDSTGLTATQHIALTITEPTTSSAPAWYL
HNDSTMCRTTTNPTGNLTIEGGSSNLWIADEPAQRDLTFPPGVWTGRITLETPLASGESF
SVAVGNCSGDIFTGSGSAVINGDGSRAFDFQITADSFEIVKDDYLAVNITDTTTGIEVKT
GGTQSYLVLLDNAPPYPVPELPGAFLIMVGLLILVGFVGRRW
>A0A346B8C9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia caffeinilytica|TrEMBL
MSSHHSDPAFNPSRRGALKCLAYGGVGTVFVLAGGILTPVELALAADEKSASASGGIPLF
LQISDSHIGFNKEANPDVAGTLKQTIDYVNAMPVKPALTIHTGDITHLSKPAEFDLAAQL
MSGLNITELHTVPGEHDVTDGPGTEYFSRFGKASDNKGYYSFDHNGVHFVALVNVMHFKP
NGLGGLGDDQLAWLESDLKGRSSSTPIVVFAHMPMWTIYEPWGWGTGDAGQAMSYLKRFG
SVTVLNGHIHQIVSKVEGNITFHTARSTAYPQPTAGNGPGPGPLTVASDQLPKMLGVTSI
KIAHHPLKATLSDTTLV
>A0A2R3FG40|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas syringae pv. tomato|TrEMBL
MPSAALSSSVLLVQISDSHLFAEADGALLGMSTRDSLEKVVDQVLAEQPHIDLVVASGDI
SQDGSVESYEAFRRISGRIDAPARWFAGNHDELPQMEHVAQGEGLLDPVVDIGRWRVTLL
DSAVPGSVPGFLADGQLQLLERSLSEAPDRHHLVCLHHHPVAIGCEWMAPIGLRNADALF
AVLDQFVRVKAVLWGHVHQEFDQVRNGVRLLASPSTCIQFAPGSVDFKVDTLAPGYRWLR
LHDDGRLETGVSRVVGMVFEADYGGTGY
>A0A3S7NT64|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas caviae|TrEMBL
METELPQAPDGSVRLLQITDTHLFASAEGRLLAVPTAQSLAAVLERVQANEHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHHGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRVASQVWRLPLGQFVPDPNATGY
>A0A2N7WVV3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia rhynchosiae|TrEMBL
MLLAQISDLHIKRPGALAYRRVDTAAYLARCVAALNALDPRPDAVIMTGDLVDQGDPQQY
EHLKTLLAPLELPYFLLVGNHDDRAALRAAFPDRAELQTGGEFVHYAVDVGALRIIALDS
LVPGQSAGTLCDARLAWLAAQLDAASGKPTVVALHHPPFACGIGHMDALRLDPVAADKLA
ALIARYPNVERVICGHVHRPMFVRFGGTIASAVPAPAHQVALDLRDDAPSAFVMEPPAYA
LHRYDPATGIVTHHAYVDAADGPYPFYEPEGALID
>Q2NWD1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sodalis glossinidius (strain morsitans)|TrEMBL
MESLLKLPVARGANIRILQITDTHLFAGEDETLLGVKTFRSYSAVLKAVQAEQRHFDLVV
ATGDLAQDHSPQAYRHFAAGIARLPAPCVWLPGNHDFQPAMVDVLAECGISCAKQVLIGD
EWQLLLLDSQVYGVPHGELSDYQLEWLARALASQPERHTLLLLHHHPFPSGCIWLDQHSL
RNAHMLAEVLQPHQRVKTLLCGHIHQELDVDWLGRRVLATPSTCVQFKPHCTNFTIDTLG
PGWRYLDLLPGGLLQTEVHRLDGAEHQPDTDYEGY
>A0A3R8SNA7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Java|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A617JHH7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella derby|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2I5TDT4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia sp. (strain ATCC 39006)|TrEMBL
MESLLTLPVARGAKVRILQITDTHLFLREQETLLGVNTYRSYRAVLDAIEAQGYEFDLIT
ATGDLAQDHSLEAYQHFACGIRRFAVPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
DWQVILLDSQVFGVPYGELSDYQIEWLERCLAAAPHRFTLLMLHHHPLPSGCSWLDQHSL
RNAHSLNAVLVRYPRVNTVLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCTSFTIDNVS
PGWRYLELFPDGRMETQVFRLEGDEFRPDMDSDGY
>A0A1X0L7Q1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mycobacterium persicum|TrEMBL
MHRLRAAEHPRPEYILLHISDTHLVGGDGPLYGAVDADGRLGELLDQLTHSGMSPDAIVF
TGDLADTGEAQAYRKLRAVVEPFATELGAELIWVMGNHDDRAALRSFLLDEAPSMAPLDR
VHMIDGLRIITLDTSVPGCHHGELRRSQLSWLATQLATPAPHGTILALHHPPIPSVLDLA
VTVELRDQAALGRVLEGSDVRSILAGHLHYSTNATFVGIPVSVASATCYTQDLTVAAGAT
RGRDGAQGCNLVHVYQDTVVHSVIPLGSGKTVGTFVSPAQAKRQIAESGMFIEPSRRDSL
FSQPPMVLTPAARPGPAR
>A0A6L3Y692|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter hormaechei|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEKRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGD
QWQILLLDSQVFGVPHGELSDYQLDWLETKLAAEPNRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDGVLAKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLTGAQFRPDTASEGY
>A0A7D7HHV5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYQHFAEGIARFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLVDARFQPDTASEGY
>A0A3K5GLH3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPYQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A737KAI6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Paratyphi C|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5R8R0H8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas edaphica|TrEMBL
MPSVSAVNPDASVLLVQLSDSHLFAEADGSLLGMNTRDSLQRVIGLVREQQPQIDLVLAT
GDLSQDGTLESYQLFRDLTRQIDAPARWIPGNHDEPQIMAHAAVHSDLLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDSQLQLLAQALSEAPNRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVKAVLWGHVHQEIDRERNDVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERVKGFEFTVDYGSNGY
>A0A5Z8LSY1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDVDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A4S2BK66|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas stutzeri|TrEMBL
MPGAPVTAVEDSVLLVQLTDSHLFAEADGKLLGLSTGDSLARVVELAFAEQPRIDLILAT
GDLSQDGSVASYQRFRQLTERIEAPARWCPGNHDELGAMREAARGSALMEPVLEIGGWRV
VMLDTLVAGSVFGMLRGDQLDLLERALSEAPDHHHLVCLHHHPVSIGSRWMDRIGLRNPE
ALFEVLDRHDNVRALLWGHIHQAFDQSRKGVRLLATPSTGVQFTPRSEDFQVDSAAPGYR
WLRLYADGRLETDVSRVSGIDFEIDYSVKGY
>A0A286XG22|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cavia porcellus|TrEMBL
MTAKNSSKELTASEPDVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRK
LLVNKSIRQRRRFTVAHTCFDVENGPSPGRSPLDPQAGSSSGLVLHTTFPGHSQRRESFL
YRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGATNK
RSPATSQPPVSRVSLQDGNTIRVWSIARCCW
>A0A558NQD4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Thalassolituus sp. C2-1|TrEMBL
MYSLDTENTLRLVQITDTHLNGPEEGHLLGMKTLHSMHCVLDIVRQERPDIDTIIVTGDL
AQDGSVRAYQHLHNALQPFACPVFWFEGNHDVPASMQEVAEDTEHLQRIVRSKHWQLILL
NSQVEGSVYGRLAPDQLELLERALSERPDLHSLVSFHHHPLPMGSRWIDRIGVKNADEVL
AVIRRHSNVRCVLWGHVHQESDQMIDGVRYMSTPSTCVQFTPKSEEFSVDTLAPGYRWLD
LHADGSIDTGVSRVEGIEFEIDYSVKGY
>Q4RHD9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Tetraodon nigroviridis|TrEMBL
MSQRKLTRQPRLWEGPEGPPQAPSFTSPVSPVDQSRGQGGSSLFRRMKLNRSIQERRRSC
HCVHSFDAENGPSPGRSPMDSQASPGLVLHPSFPQSQRRESFLYRSDSDYDTSPKTMSRN
SSINSEGHTEDMIVTPFAQVLASLRTVRSNFTILANVTTPTNKSVSYCRTPPFP
>N1NPN1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus nematophila F1|TrEMBL
MESLLEVPVAEGATARILQITDTHLFANKGDSLLGVNTYNSYHAVLDTILEQNLDIDLIV
ATGDLVQDQTIEAYQHFAEGMARLPASCVWLPGNHDYQPAMVDTLAAAGISPSKQIFIGQ
HWQLIMLDSQVQGVPHGELTDYQLEWMKKCLDEHSERQAIVMLHHHPVPSGCTWLDQHSL
RNAPELSEFLKGQTQVQAILCGHIHQEIDDMWNGIRVLATPSTCVQFKPHCTNFMLDTEA
PGWRYLELSVTGKQEARLQTQVHRLKSNEFCPDLDSDGY
>A0A7J8I2S7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Molossus molossus|TrEMBL
MPLVDFFCETCSKPWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVE
IPSPTIKDGEKAPWQRPSQQPPPPGPQFQPMSQITGVKKMMRSSSLTDSGIPRFGVKTDQ
EELLAQVGGAQWRWAGKGQGFPGERLGVGLA
>A0A7J8J2I5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Molossus molossus|TrEMBL
MAQQATSPDTLTVPEVDNPHCPNPWLNEDLVRSLRENLLQHEKSKTARKSASPKLSPVIS
PRNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFV
HSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAAL
TNLPDRAPSKRSPMCNQPSINKATITGLYNGIIAFP
>A0A2M7HMI0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. CG12_big_fil_rev_8_21_14_0_65_47_15|TrEMBL
MLKEAVSYSIAEEESVRIVQVTDPHLFADPEAQLLGVNTGKSFAAVLNTIRAVDYPAHLM
LATGDLSQDYSAESYRQFVTAVTPLNLPCHYLPGNHDDPRIMFLHMQGEQIFGQQRILAG
KWQILMLDSTVRGKPGGSMAESQFELIEHAIAAHPEYHTLLVMHHNPILVNCTWLDQHCM
DNGVEFLARVSRYPQVKGLLWGHVHQRIDTHYDGPHGALKLMATPSTCIQFKPLSPYFAL
DGLQPGYRLLELKADGSISTNVYRVPGNHFSPDKDSSGY
>A0A7H4ZG40|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia enterocolitica subsp. palearctica serotype O:3 (strain YE-P4)|TrEMBL
MESLFKLPMASEARVRVLQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGISRLPAPCVWLPGNHDFQPAMVDALANAGIAPSKHVLVGD
NWQILLLDSQVFGVPYGELSEYQLEWMERCLMAHPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLNWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGRLETEVRRLASDEFCPDMDSDGY
>A0A5J6WP05|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moritella marina ATCC 15381|TrEMBL
MSADISKLTAKHDVINLLQVTDTHLFATAEKDLLGVKTQLSYRHVIDAILQNQQVFDAVL
ATGDISQDNSLASYQYFAHHIKRLDKPCYWLPGNHDNIPLMAEALKAEGVLPDKSKVVGD
WQIILLDSQLTGSPAGYLSPEQLASLDEQLSAHADKHALVVLHHNTYPVGCKWLDQHILR
NADEFLAVLAKHPQAKHVLFGHVHQQIDKTYDGIHFMASPSTCFQFKPHCDEFTLDSRAP
GWRYLQLHRDGSINSQVWRLSSNDFNPDLDSKGY
>A0A6S4VJE5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas veronii|TrEMBL
MRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHPYEVILATGDLSQDHSPESY
QRFASMMAPLGRPIYWLPGNHDDSPLMTEQLHAAGISESKQLVGNHWQVILLDTQVRGKP
HGMIGDHQLEALDRALRQYPDRHALIALHHQAVPVGCAWLDQHNLKNADDLFAVLARHPQ
QKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGWRYLTLYPDGRIA
SQVWRLPVGQFVPDPNATGY
>A0A0B8P8I1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio ishigakensis|TrEMBL
MEPRIVETGESVQLVQITDTHLFEDSEGTLLSVNTEHSFHAVVEDVISKELAFDAIIATG
DISQDHTAASYEKFVEGIKLLVKPCFWLPGNHDYKPSMGSVLPSAQIQACNHFLAGEKWQ
VILLDSQVTGLPHGYLEQEQLAYLDDMLAEYPERYSLVLLHHNPLPIGSAWLDQHKLQKA
VEFWQVLDRHKNVSAVLCGHVHQEFQTEHHGVQVLATPSTCIQFKANNDEFALDNLSPGW
RHLSLHSDGSIESKVYRLPEGSFVPDFEAEGY
>A0A663F442|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aquila chrysaetos chrysaetos|TrEMBL
MPLVDFFCETCAKPWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQHEVE
IPAPGPKEREKKRRQPPPMGQISGVKKLPPGSGPGGSSVPRFGVKTDREDLLGKELDSLN
KWGLNIFRVSEYSNNRSLSCIMYTIFQERELVKTFKIPVETLLTYTLTLEDHYHADVAYH
NSLHAADVMQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPDSELALMYNDESVLE
NHHLAVGFKLLQEENCDIFQNLSKRQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETK
KVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKPLALYRQWTERIMEEFFRQGDRERER
GMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILETLEENRDWYHIPD
PRSPPNLPLPPSPPPPPQHRFQFDLTLEEDEEGQEPGVYPPPSSCNAPRLVHQPYVTPPE
QPPGGRRPPEEEEEEEEERNGLGGGIPWGWAFPYLGGGARPGGGGMCNGAGGGVWGVVGD
ILPKRIWGVGGGRGGSGLACAPPPPHDVAL
>A0A811T350|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Argoarchaeum ethanivorans|TrEMBL
MTVKIVHLSDIHTANPHFLPEMALKVVERINEINPEILIITGDLTESGYPFEFECAKSYI
EKIDCASKVIIPGNHDVRHVGDLCFEEIFGSRSKVKRYKGITIVGIDSTQPDIDDGHIGR
DKYEWIEKCFDTDDFKIFALHHHLMPVPFTGRERNIPVDAGDVLELLVRCKVDLVLSGHK
HVPWVWNLNGMTILNAGTACTNRMKWSIPQSFNLIELDKEMLKIYKIYSKGGHELILEKP
HNFVVRG
>A0A1V3K046|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rodentibacter pneumotropicus|TrEMBL
MKNTFVYRAEKPMVKLLQITDPHLFKDEKNELLGVNTQASFAQVLKEIQQEKREFDAILA
TGDLVQDSSDEGYQRFVNMIKPFGLPVFWIPGNHDFQPKMVENLNQSPMEKAKHILLGEY
WQVLLLDSQVYGVPHGELSQYQLDLLKTTLEKYPECHTLIVFHHHVLPTNSAWLDQHNLR
NSHDLFDVLSAFKNVRGILYGHIHQQVDSSWQGYQVMATPSTCIQFKADSQHFALDDVQP
GWREIELHSDGTIVTTVKRIRQARFLPNMQEEGY
>A0A659K6X8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. E4208|TrEMBL
MESLLTLPLAGESRVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADSRFQPDTASEGY
>A0A7Y1DB91|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas proteolytica|TrEMBL
MPSVSTVNPDAPALLVQLSDSHLFAEADGTLLGMNTRDSLQRVIELVRARQPQIDLLLAT
GDLSQDGTLESYQLFRDLSQQIGAPARWIPGNHDEPQVMAQATMGSALLESVVDVGNWRI
TLLDSAVPGSVPGYLAEPQLQLLAQALSEAPGRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRQRNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHPDGRLETGVERVEGFTFTVDYGSNGY
>A0A7U9RML9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lactobacillus johnsonii|TrEMBL
MKIIKKTKGMIDKFSGVTRKMMRKKNNIPFDGMQKYMTVGEYNVGAPEGTPHGEEYKLIV
YKDTDNVLHQALRSINASDLAPAYVRKFDKRLNRYTAFVNKKTGRRYIVEDQLDQLVDYV
KKHSRDGYNSINIGVLTDTHYKDADSIDFYGHNGLRHVKEFNYLEDKDVLDLKAHLGDWM
DGSDPGLVGEAELISLSRTFRSKKTNFAVIKGNHDENDKFDEHHDLRASFPENEFEDIMW
PSMYAQDGIHYITRKHGVAYFDKDDVRIITVNTSDLPYELDEQGKKKYDTKLALAIREDQ
MQEIIEILENSNGKTIIFMSHANPITRKGTNALKFNGRSLHELMVAFNQREKGYLNSRDV
PPEFTLANSFDFTKIKNAKIVAYLCGHRHTEDQYRINGIQYIFFNCSALMGPNHALTTQY
NKRWNRQMDHANEAAGYIVNVDVQRHLLQVFGYGAASKRRFYRI
>A0A3D1C0E9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella sp|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADKRFQPDTASEGY
>A0A5E4VTR5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea terrigena|TrEMBL
MRLHILSDLHLSVAPLAAPEVEADITILAGDISRPAQAIEWAKALGRPVIYVPGNHEFYG
ATLAGTLAELRHLTAGTDVHLLERGSVVIGGVRFVGTTLWTDFALYDADGKHDAVVEESL
KFVRDFTRIRVGDPAVPWTDLPCFSPDDCAALCRENVAWLARALAAPHDGPTVVVTHHAP
TPQSIHPRFSGSLVNPAFISDLTSFVESSEAALWIHGHTHDSFDYRVGHTRVLCNPRGYC
FEGRVENAAFDPTLTVRV
>A0A5E4XBQ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea terrigena|TrEMBL
MNQEQTRRIKVAHLSDLHFSIGNLLEAGQCFGSAVSTAISERVDVAIISGDLTDHKQDAH
SAALHQLMQELRRLADHCPVLILQGTFLHDYPGMLAIYRFAGGKYPVETVDKIGQVALVG
TQWRYVSPGDSLDDARLLVSCVPTVNKSDLVSSVGAEHVAQAMGDVLAGLMQGVFAPQNI
AASAAGVATVTVGHGTVSGALTEHGVPMAGKDHEFSLGGLYAAQSTATMLGHIHRHQSWD
REVGGFVQRVAYPGSIGRFHYGEEGKKGFLIWNIGPRDCDFEFRETPARVMVDFLFDGVP
DMAWLEEQAASCVGSFVRVRYSVDAELAVTVDKQAIEQVLAQAAEVRIEPKLLASQRQRC
SGISTLSTLAEKVEKWCKSTDNDASVVVPRVRLLGTSDARSIATSLIKELFHEAESRTHE
HRDDAGHAVDPFARAERGLDHSAGRELAQ
>A0A2H5VN86|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR08|TrEMBL
MMSLRRPKPWRRGVTRRVARTLLELARQAVDETRDIEIVRERVWLSGLPESFEGFTLVHL
SDIHHSAFVDADYIAHAVALANRLAPDAIVLTGDYVSHSRAYIGGVAELLGDLCARVGVY
AVLGNHDFWTGPEALTRALRRRGIEVLRNAHTYVRRGGEALGLVGIDDLTVGEDDLLAAL
RGLDRRWPTLLLSHHPNILWSAAHARVALVLAGHTHGGQINIPSWRRRLRRYWPLLRGHG
RYGPTQIYVNRGLGTVLIPVRYRCRPEITLLELRRAPEAGGSV
>A0A1I8PV34|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Stomoxys calcitrans|TrEMBL
MRNCFTKITNIFRKSALPHSSDHDYDSEMGNLQQSGGEAQSSMEPTTTSEEQKSKGTQTP
PYVRSTSSISLSENHKPAIGHNGVDSADNESIHQLVIKNRDSFHDKHEKVSYITKQTISI
GDAVDDRHRLFQSLFKKRRRTMKEAGNSGNGHSCRQDQIGARLLPTVDHQFSRGKHMYHL
SDAGEDQERSELKQPYGETRKLLLTSNPFSVLEENEEGSYSAKAKFVKNDKYVEYCVGEN
NNDKVHDISLMLEKGTNSFVSNDVDSSNALIFPSNNPDSCTDSPNAAKTPEEIEYEAKVA
AESEDMMTPLPTNTKHHPFALGRNLRPEIAEVIRSLDANTLRINNLTVEDKLELLRRFES
TQHARRSGRGNSHVRSMPPAGHSIQIDLGLAQTRDQHTDDLSDLSTDGVILRRKNSHTSQ
SNLYERRQPKSPKLKLILESKWKEGTFGGASDATICEYKRNVCDVKYPTVLPPNPQLKAL
LVFYKSDNICEVVQQACNRQQLEVTLVKSKENAIENLCSAVECFHIIIIDARSPKHLDAE
HIARSIRHMSGHHFTTIIAVVKKSTFDRDDVINALLDAGVNRCIAETTSLSMCAMEIKQI
LHSIVRPHNVISTQQALYTALHRLKEVLLITDDLLRIQYANRSAERLLNMRLDEVINKPL
SEIFVSDVSTINNSVQGKGVREFDGILTVKRKNQDGIPMHVRVVPVACIGRTTTHFVYNF
DVPGGQMDFVATLPQPKEAPRGSLHSIRRGSFDVRSIASDGLRRTSLAKLTSLPLEAPIT
KIINLLSQVQENCSADEARLIDKVMEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPN
VYSSRRSSNDSIVRANCTNRQSTVMPAKMKATPLIMEILEESLNWEFNIFKLEEVTERHP
LLYLGMEIFRRFDVFATLNVDESICKNWLAIIERNYHADNSYHNSTHAADVMQATGVFIS
QLAAKDLVMDRLEEASALIAAAAHDVDHPGRSSAFLCNSNSPLAILYNDLTVLESHHAST
TFKLTLGDDNANIFKNLDTETYKAARTTIIDMILATEMTRHFEHLAKFVSVFGAELEPRD
IVQSEEESSVLMRRMLIKVADVSNPARPMICCIEWSRRIAEEYFTQTDEEKSKNLPIVMP
MFDRGTCSIPKSQIGFIEYIIQDMMHAWDSFIDMPELITYMQINYSQWKKFEEQGVHTLA
EVKAKQMSLMNKKSALK
>A3D8I8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella baltica (strain OS155 / ATCC BAA-1091)|TrEMBL
MLKEAVSYSIAEGESVRIVQVTDPHLFADPEAQLLGVNTGKSFDAVLNTIRAVDYPAHLM
LATGDLSQDYSAESYQQFVKAVTPVGLPCHYLPGNHDDPRIMYLHMQGEQIFGQQRILAG
NWQILMLDSTVRGKPGGNMAETQFELIDEAIAAHPECHTLLVMHHNPIVVNCTWLDQHCM
DNGAEFIARVAKYPQVKGLLWGHVHQCIDTHHNGPHGSMQLMATPSTCIQFKPLSPYFAL
DSVQPGYRLLELKADGSINTKVYRVPGNHFSPDNNSSGY
>A0A2Z2P3D5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Granulosicoccus antarcticus IMCC3135|TrEMBL
MITIMHLSDLHFGTESAQVLSSLIRQVRELSPEVVVISGDLTQRAKWREFRAAKRFVEEI
DKTDTEVIVVPGNHDIPLFNPVMRMFSPFHRYRSVFGSTRVAVQHVGRVRFITVNSVRRE
RHASGFITSRRRNEVARVAQECAEGDVNVVVTHHPLGINSLSDKGDAHHGDSETCRAWHG
AGVNLILSGHVHRPFLLDATEQLIANTGEGEPPMWILNAGTAISKRVRHDHPNSYNLVKI
DERAGFDGIAVERWDYRVEGRQFFQQATRSVELRSVPSGSIGK
>A0A4P8QKE2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Brenneria rubrifaciens|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAIKARREAFDLIV
ATGDLAQDHSLAAYHHFSRGIRQLPAPCVWLPGNHDFQPAMVDALAEEGIAPSKHVLVGD
KWQIVLLDSQVSGVPHGELSDYQLEWLERCLKNQSDRFTLLLLHHHPSSCGCTWLDQHSL
RNAHNLAAVLTRYPRVNTILCGHIHQEMDLDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLMPDGRLETEVFRLSGSDFLPDMDSEGY
>B0BTM2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinobacillus pleuropneumoniae serotype 3 (strain JL03)|TrEMBL
MSSFYSLGKKEPVVRLLQITDPHLFTSESETLLGVNTTDSFQAVLDQIRQSEFEYDLVLA
TGDLIQDHNPEAYHRFAQMVKPLAKPIFWLEGNHDLQPHMGLYLAKYPHISPAKHILAGE
KWQIILLNSQIAGAASGHLSFGQLSWLDKKLAEYPDRYSLVVLHHNILSTRSAWLDQHCL
NNSEQLAEVLRHYPNVRAILHGHIHQEVDDIWQNYRIFATPSTCIQFKPNCDDFTLDLLP
QGWRELNLFDDGHIETQVKRLNSNEFLPDFKSKGY
>A0A545TFV2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Exilibacterium tricleocarpae|TrEMBL
MRLVQVTDCHLGSNPGDDLLGLDTDLSLHDVLALIREEQPSPDLVLATGDISGCADLPAY
QRFLKLIEAQFTVPMAWLAGNHDTPDVMEAALEGRPMPKVILAGNWLVVLLDSSVRGHEH
GDLTTAELTFLQDTLNRYSERHTLVFLHHQPVPIGSAWVDQYIVRSAGRFFDIVDAHPQV
KGISWGHVHQEFHQIRNGVSLWSTPSTCVQFKPNCDEFTVDHTMPGYRWYDLHPDGRLET
AVSRIAKKDYPIDYASSGY
>A0A5J4RI82|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MNMIRFLQFSDIHFLFCEDTEDEYAQMRIRFIEDLENVKKQLGVVDYVLICGDIACKGQK
NEFNKAKIFIESVSKALEVDGNRPNIFLVPGNHDIDRQSYKATRDLLRPSLLDKKNDEFL
QAIKHTEPDTLKILYAPLLAYNEFAQPYSIDEVSETIMIGDIDEHYFDGKNYYWKFCLGK
ESNYTVNLYGLNSTLTCDGKEAAKKDLKEGNHLTFLPKPAYNIQTYSNEINISMMHHPLD
WLKDENHACTIFDDRFKLQFFGHMHVQNSQSNKAVKIFSGAFQPEKEADIKDCPPVFNVI
KLDVEGAVMIVELESRKWDGAYFIKYKEESKTMSVSLAAPNNWSETTQEEAKKEPIVIEH
IMKPIHEINYMFINSDRQREIIERLVPGTFDDERSERANCLLFLKAVKERGLYQQLLNEL
NK
>A0A5J4T0I4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MFAIVLGLHFYVFYRLWCMMPVSTTMWRTLFMVSAVIVVSSFFLSILIGNNLPSSVTSIM
YRVGTSWFFIFVYLLIIFLLLDLLRLTHLLPIHRFMYGSWIGFGVLAGFLTVVMSLGYFK
YIDKEKVELFLEIDKDVAIPSLKIAAISDLHLGYGIHKKEFEQWVQLINKENPDIVLIAG
DVIDNHPRPLYEQNMAQAFKQFRTKYGVYAVLGNHEYISGVSKSIDFLKEAGIIVLKDSI
AFIDDTFYIIGRDDRTNKARKSIKELTGTLDKSKPFIMLDHQPYHLEEVKKNNIDLQISG
HTHHGQILPISWITNRMYEKSHGYLKKGNSHIYVSSGIGIWGGKFRIGTQSEYIVINLNI
KQNH
>A0A8G1TZT4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter sp. K91|TrEMBL
MARIHSLTRRDDAPAMLVQLTDSHLFGEPETSMLGVNTDASLRAVLRQIEADGKHPDLLL
ATGDMSQDGEAAAYRRLARVLSEAPALAQASIRCLPGNHDLPAVMRQELPQWSVPVTDVG
AWRVVALDTTVPGSNAGHLPASQLDLLEAALAEAPGRHTLIAMHHNPMQIDSHWHDSMMI
DNPQALFKLLTRWPQVRVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNMA
PGYRWIKLYQDGSMATGVRRVQDALWHGARTAADNAQAA
>A0A507WFN7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moraxellaceae bacterium AER2_44_116|TrEMBL
MLKKNTQRPLRVVQVSDSHLFASTEGRLLGLNTEDSLRLVLEKVQREQTHIDVILATGDI
AQDASEAAYTRFQQHLAQFHVPNYWLQGNHDITQPILNTLNDKTHLSPCVIHKDGWQIIM
LNSSVEHEVPGNFAPNELQFLQQALSASTRSHVMVCLHHHPIPMDCAWLDNQVVANADAF
WQIIDQFSHIKAIIWGHVHQESDRVRKGVRLLSVPSTCVQFKPLSDDFAIDDLSPGYRWL
DLYANGDIVTQVSRVEGVKFVVDWSVRGY
>E3G3B8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter lignolyticus (strain SCF1)|TrEMBL
MESLLNLPLAGGARVRILQITDTHLFAEKHETLLGVNTWDSYQAVLAAIHASQRESDLIV
ATGDLAQDHSSAAYQLFAEGIAGFAAPCVWLPGNHDFQPAMYSALQDAGISPAKRVLLGE
NWQILLLDSQVFGVPHGELSDFQLDWLEQRLSESTERHTLLLLHHHPLPAGCSWLDQHSL
RNAGALDQVLSRYPQVKNMLCGHIHQEMDIDWNGRRMMATPSTCVQFKPHSANFTLDTIA
PGWRWLELHADGTLTTEVCRLTGAQFRPDTASEGY
>A0A738CR88|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae serovar 30:1,z28:z6|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGD
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A8B6GJH2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mytilus galloprovincialis|TrEMBL
MLQLNRRKSCFDVENGTGPGRPTLEGSSPSSSRLVLQNLPQRRESFLYRSDSDYDLSPKS
VSRHSSMQSEIHADDLIVTPFAQILASLRSVRNNYISLTNVQAPRER
>A0A837KDV0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella aerogenes|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLHDAGISPAKRVLLGD
HWQILLLDSQVFGVPHGELSDFQLEWLEHQLNAEPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDQILSNYPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGALTTEVCRLSGAEFHPDIASEGY
>A0A7X4X243|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. V30_P3S12P165|TrEMBL
MNVSPSLSPSDHIKLVQITDTHLFAPDDGCLLSVNTADSFRAIVQAIIEQQIPFDAILAT
GDISQDHSAESYQRFAAGIRDLQKLCFWLPGNHDYKPNMGSVMPSAQIQALEHVLLGKHW
QMVLLDSQVVGVPHGRLSDYQLGLLDEKLTQYPDRFTLVLLHHHPLLVGSAWLDQHTLKD
SDAFWHVVGQHRNVRAVLCGHVHQAMDCEYQGVKVMATPSTCVQFKPNSDDFALDLCSPG
WRELELHHDGEVSTQVKRLRKGAFVPDFTSSGY
>A0A8J7KD32|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Elainella sp. C42_A2020_010|TrEMBL
MPLLSPLQVVQLSDTHLFADPNRELLGLSTADSLKTVLDSVRQIQPKPDLLLLTGDLSQD
ESAKSYERLRDLLEPLQIPAYWLPGNHDYPPLMAQILVTPFIATDKVFQGGGWNFILLNS
MATGKVYGELSAASLDWLEQQLQQCPVQPTLIALHHPPCPIGSNWMDQIGLRHPEALFAV
LDRYEQVKLVLFGHIHQEFTATRAGVQYLGCPSTCVQFKPQETNFAIDDQRPGFRLLSLY
PGGEFTTTVKRVNYQPLPDLAATGY
>A0A523K812|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MNNHFKIKPFHQDYAELLQITDTHIFADEKETLDGVDTQSSLKEVLNLARNNDWPVDAVL
VTGDLAHDPVTIVYERLLDILTDIDKPIFWLPGNHDDPKLMYQVLNKKNIHTAKSIEIGS
WIVVMLDSFLANTHAGYLAQDELDFLDKILNENLDKHVLICLHHPPVEIGSVWMDSMRLN
NPEDFFNVLDKYDHIKAVLWGHIHQEFFSERHGVTLMATPSTCVQFMPGAGQYTKDGRAA
GYRHLRLNASGEINSVIRRLNEDGA
>A0A2J8WPQ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pongo abelii|TrEMBL
METLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTF
LDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLA
KELEDLNKWGLNIFNVAGYSHNRPLTCIMYAI
>A0A7U3NLT4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anabaenopsis elenkinii CCIBt3563|TrEMBL
MNQVSPISIAQITDIHLFGSENHKMLGMPTIKSFQAVVDKLHSLRNEVDLLLLTGNLSGD
GNLQSYDNLQNLLNPLQIPAYWLPGNNDCAIAMDNILNMGMISRRKSFERGGWNFILLDS
CVPGCRHGYLGAKTLDWLNRELTILGDHPTLVGLHHPPFAVNSPWLDHSSLQNPQELFAV
VDRHPQVKLVLFGHIHQEFQRQRGQVHYLGTPSTGLQFRAQSPTLRIDSKYPGFRLLKLY
PNGMWETTVERVPYFQPLELVATVS
>A0A0T9T7T4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia enterocolitica|TrEMBL
MQKQGHHLESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTSHSYRAVLDAIIAEQ
HPFDLIVATGDLAQDHSVAAYQNFAKGIARLPAPCLWLPGNHDFQPAMVDALAYAGIAPS
KQVLVGNNWQILLLDSQVFGVPYGELSDYQLEWMERCLVAHPERYTLILLHHHPMPSGCT
WLDQHSLRNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTN
FTLDTVAPGWRYLDLLPDGRLETEVRRLASDEFCPDMDADGY
>A0A1C3JCM1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio celticus|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPHGQFLPDFKASGY
>A0A2J8NHH1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pan troglodytes|TrEMBL
ISFDVENGPSPGRSPLDPQASSSAGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKAMSRN
SSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQE
ESYQKLAMETLEELDWCLDQLETIQTY
>A0A427GZM0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas stutzeri|TrEMBL
MPGAPLTVVEDSVLLVQLTDSHLFAEADGKLLGMNTCDSLKRVVELAIEEQPRIDLILAT
GDLSQDGSVASYQRFRQLAGRIEAPARWCPGNHDELGAMREATRGSELMEPVLEIGGWRV
VMLDTLVAGSVYGMLRGDQLELLDRALGEAPKRHHLICLHHHPVSIGSRWMDSIGLRNPE
ALFEVLDRHDNVRALLWGHIHQAFDQSRNGVRLLATPSTGVQFTPQSEDFQVDSAAPGYR
WLRLYADGRLETAVSRVSGIAFEVDYSVKGY
>A0A1A8DIH7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothobranchius kadleci|TrEMBL
MSSNELSVEMDSCIRTFKEHMHLELEPPKMPGVMGGKRGATSPKLSPRSSPRLFRKLMVN
KSIRQRRRFTVAHTCFDVENGPSASCSPLDPQASPGSGLVLHTNFPGHNQRRESFLYRSD
SDYELSPKSMSRNSSIASELHGDDLIVTPFAQVLASLRSVRNNFTILTNVQCPSSKRSPA
ATTQPPITKVCLPDEAYQKLAMETMEELDWCLDQLETIQTYRS
>A0A7U7EDJ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas stutzeri|TrEMBL
MTSIVQISDTHFGTEQPSVVQALEDHVREHRADLLVFSGDITQRARRGQFASAAAFVRRL
EANGVGETLVIPGNHDIPLYNLFARLFTPYGNYRRHFGDELEPVFENDDMLVIGLNTTHP
RRHKDGVVTGRQVERVAQRLADGNPHKIRIVVAHQPFGAMVPSDLSNLQHGAEPALRRWA
EHGLDLVMGGHIHLPYVLPLSKQYSGLAREIWMVQAGTTLSTRLRGTSPNSFNRLKLHPG
EQKKVCVERWDLLDGRFVLGSHFNLSW
>A0A2R8CKS1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kushneria phyllosphaerae|TrEMBL
MKVAAIADIHGNLMALEAVLADIKKQGVDLTVNLGDLLSGALQPRETAEYLMSLQLPTVR
GNHERQLLDDTRPMGLSDSLARSAINDTQLQWLKALPASLNIEQEILLVHATPADDVTYW
LETITAGGRRAATSEEAIARGGEPNVSLVLCGHTHIPRDLMLPNGTLIVNPGSVGLQAYD
DEAPLPHVMETGSPHARYAILIRTGTAWRVEYRQVAYDWEGAARLALQNGRKDCVAALRH
GRVVMPG
>A0A1E5FWU4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus 12E03|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHALLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHTNVKAVLCGHVHQDMNLDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPHGQFLPDFKAAGY
>A0A7Y5YFC2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. C1C7|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEADGALLGMNTRDSLQKVIELVRAQQPRIDLILAT
GDLSQDGTLESYQQFRDATRQLDAPARWIPGNHDEPQIMAEAVVGSALLESVVDIGNWRV
TLLDSAVPGSVPGYLQDDQLQLLARSLSEAPQRHHLVCFHHHPVSIGCAWMEPIGLRNPD
ALFAVLDRFPQVRAVLWGHVHQEIDQFRNDVRLIASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGRLETGVERVTGFDFQVDYGSNGY
>A0A5A5RTE2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcystis aeruginosa NIES-2520|TrEMBL
MRPFWLESLQVERLTIAIASLPAHLQGIKLVQWSDLHCDAQHLPVAVLQEAIAITNQEKP
DLIFLTGDFITYSPRPIFALVESIKALKSQGGIYACLGNHDSYLPHARETVRAALTSVGI
RVLWNEIATPYGENFPIVGLADYWSGEFLPQILEQISPDIPRLVLSHNPDTAMLLRDWRV
DLQLSGHTHGGQVTIPGIGSLPIVLEKLRRSLPEPYCQWVPFHRQFSRVVRYWQWSEGFH
RVGENQLYVNRGLGTYFPGRLFCPPEVTVITLINSSQS
>A0A7G9YVI7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methanosarcinales archaeon ANME-1 ERB6|TrEMBL
MRLKSLIDKPAMVVENESKTLVIADLHLGIEAELREKGINIGSQTEKLLERVITCVKAAE
PDVILLLGDVKHAVPRISWMDRKEVPFFLAGLAEYAPVYVVKGNHDGHLNRLLPKTTEPE
RKPEHEVCIKSTRGFLFDGVGYTHGHSWPLQDLFSAKYILIGHNHPRIKLASSQSRYRST
RSVWIRAKCDYDAVKEHYTELRKSGWNDPWVIIMPAFNEICGGITFNAPTKRLLGPIASK
LLRLEDMEVYLLDGTYIGKAGELEDSYSENY
>A0A5R9GL40|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mariprofundus erugo|TrEMBL
MSIRLLHISDSHLYSDPAALLKGVCTYQSYKAVLADAWQQFPDIDCLILGGDMAQDEKPA
TYATIARLLPEWQAPVMITPGNHASMTALNDTLIPALHRHSSYADQWQQHAWQVIALNSH
QAGHIAGRLPDEALQRLQSELSASSASHILLALHHHPIPIGSRWLDRIGLENRDALWAVI
DQFPNVRAVMCGHIHQAFDAMHGTVRVLGTPSTAVQFAPACEQFTLDALSPGYRWLELME
DGSIQTGINRISGFLPPDLNNTTPY
>A0A7L6CPB3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. RHBSTW-00994|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLNAIHAEKRVCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSALQDAGISPAKCVFASE
QWQVLLLDSQVFGVPHGELSEFQLEWLERKLMAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLVKFPRVKYLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELYADGSLKTEVCRLSGAKFRPDTASEGY
>A0A2L0TPU1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sp. ASNIH1|TrEMBL
METELPQAPDGSVRLLQITDTHLFASAEGRLLAVPTAQSLAAVLERVQANEHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGDHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHHGVRLIASPSTCIQFKPLSDSFALDESGPGW
RYLTLHPDGRVASQVWRLPLGQFVPDPNATGY
>A0A5I2LAM2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Durham|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDVDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2T5ETH4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIEPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVLLDSQVVGVPHGRLSDQQLDLLEQKLTEFSDRNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAILCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTQVRRLPNGQFSPDFDAGGY
>A0A2R6VVM9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIKPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAVLCGHVHQDMDRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTQVRRLPNGQFSPDFDAGGY
>A0A2N7L2R3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIKPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQVVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPDRNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAVLCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVNTQVRRLPNGQFSPDFDAGGY
>A0A2J7QT81|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cryptotermes secundus|TrEMBL
LCFRHGRRGTLDLENGNSSQKNQQTTGTPGGFSITNQDCTTKVLLAFGKEDFQSDAFWLA
CEKLGYECNLARTRDSVLEAFQTKSHEIVIIDTRNPKVIDGESLCRALRALKTSQYTVVV
GVVRKGTSEKEDSSIEPMLNMGFNRVIMETSGLVQCMNELLQLYLSDVQPRLQLATAQAM
HIALDKCSDVVHITDQNLNIQYMNRSSERFLGFSMKDVAGKSLLETNSVDNKELMVQQLQ
RGREWEGLISWRRKMGDSVVLSGRVIPVCSPGRSPTHYIFIHESQHMMLDKRMSGTLVKN
PELPKGSNNRKGSADMKSISSDGLRRQSIAKLHNLSIEAPITKVIALITSVQDNANIEDI
QTLDKVVDILRTTELYSPQLKDDKGKAGDPVTNDLIGALLSSGPSVTPIARRSSSDSGSV
SKIGLSRSTFKTANMSHQMKELLDTSLLWDFDIFRLEELSVKRPLVYLGMNLMDHFDVCS
SLGCEENVLHNWLVVIEENYNAKNTYHTSTHAADVMQATAGFLERERLKQILDPLDEAVC
LIAAAAHDVDHPGKSSAFLCNSNHELSILYNDLCVLESHHSALAFKLTISDDRVNIFKSL
ERDVYKAVRQNVIDMILATEMTKHFEHLAKFVNVFSIKKEDDSPDTDEEKANNLPVVMPL
FDRATCSIPKSQIGFMDFIINDMFETWEAFIEMPELLQNMQHNYKFWKEKEKCGIHRIQD
VIMMQHTVKTSGKTD
>A0A3L8PYQ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Parashewanella curva|TrEMBL
MDRESTLTNFSSTYTEKQQGCIQLLQITDTHLFASDEGQLLGVNTSKSFEAVIELAINND
HHADLMLMTGDISQDNSVESYHRFAKQSQALGLPCHFVPGNHDENYMMHQALQGKQLFPQ
KHVIFDNWHIVMLDSTIEGKPAGRVEEDQFEFVDQVIQSYPEKHLLVVMHHHPIPVGCRW
LDQHWVQNGDEFLARVGAYSQVKGIVWGHVHQEVNEVYKGQHGNIPLLATPSTCIQFTPK
SNHFALDGLQPGYRLLQLQSDGSIRTTVYRVKGERFSPEHEASGY
>A0A8E0SFP6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium damselae subsp. damselae|TrEMBL
MLTYSLPPRQSDSVVLLQITDTHLFANDAGSLLGVATKDSFHAVLAAIDHQARPFDAIIA
TGDISQDHSTESYQHFAQGIARWQQPCFWLPGNHDYQPSMKAVLPSPQIKPCEQVLLGEH
WQMILLDSQVPGVPHGELRAEQLEMLDRALAAHPERHALVLLHHHPLAAGSAWLDQHQLH
NADDFWQVLARYPAKVKSVLCGHIHQELDCMRQGVRVLATPSTCIQFLPDSDDFALDSKA
PGWRYLELTPQGDVYTQIHRLANDQFAPDLNSAGY
>A0A399DWZ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Meiothermus taiwanensis|TrEMBL
MIFGYSFVIQHHRRPLRGLQVPVRVAHLSDLHIGFFIRQGSVRRWVEATLAQQPDLIVIT
GDLTDSERSHQVLPTLTELQKLKAPLGTWAVWGNHDYRFNGYQPRYPTPLDGRSKVNPPR
VPMLSPVQLEERLRALGIGFLHNAGVQLRDDLFLAGVEDLWHGEPNIEQALAGYSSPGAC
LLLCHNPDYLYQVPRSVDLTLCGHTHGGQIVLPWYGPVFTSSLYGQKFAGGWVEDPVPAF
ISRGLGVSTAPLRVACPAELVIHDLVPLER
>A0A3G2PXI3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio owensii|TrEMBL
MQSSSDSIKLLQITDTHLFEADEGSLLSVRTADSFAAVIQEVLHRQVQFEYVLATGDISQ
DHSAESYQRFAEGIAPLKKDCFWLPGNHDYKPNMGSVLPSPQIQAVEHLMLGEHWQLILL
DSQVVGVPHGRLSDQQLSLLEEKLAENPQRHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFENVKGILCGHVHQDMNVLYNGIRVMATPSTCVQFKPNSDDFALDTESPGWRELE
LHSNGDITTEVNRLPDGQFQPDFTSNGY
>A0A3N4AW05|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. SSM44|TrEMBL
MSLAELAGTDYVCIVQLTDSHLFAADSDDLLGLDTLDSLNSVVDLVLSEIARMDLVLATG
DIAQDASELAYRRFIEASLQLPAPCHWIPGNHDDAAMMQRLGAASGMSQDWVDIGSWRIV
LLDSSVSGSVAGYLADSQLQRFDDALATAGDRHLLVCLHHHPVDIGCSWMQPIGLRNADT
FFARLAGQSAVKAVLWGHVHQAFDGERSGVRLMATPSTCVQFATDSEDFATDTLAPGYRW
LRLYDDGRIETEVSRLPPGSYLPDPGATGY
>A0A6G9ID33|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Zophobihabitans entericus|TrEMBL
MSAFLSLPIDKKIGRILHITDTHLFACENETLLGVNTLDSFNAVICEIEKKKQYYDLIVA
SGDFVQDGSKAAYERFATRITQLDIPCVWLPGNHDMLPNLQPVFNEYQIPNEKLILLGEN
WLIILLNSQVPGKAYGRLAESELSFLSETLQQYSERNTCVFLHHHPVLSGCQWLDQHCLQ
NTESLQNILKQHPQVKTVGFGHIHQNIEQQWEGRMVFATPSTCAQFKPQCNEFTVDECGP
GWRDLSLYEDGTIETQVSHIESTLFIPDLTINGY
>K0G6C4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinobacillus suis H91-0380|TrEMBL
MNGFYSLGKKEPVVRLLQITDPHLFSAKHEKLLGVNTTDSFQAVLDQIQQTSFDYDLVLA
TGDLIQDHNPEAYHRFAQMVKPLAKPIFWLEGNHDRQPQMSLYLAKHPHIQSEKQILAGL
HWQILLLNSQVANAPSGNLSFGQLAWLNSKLAEYPERYTLVVLHHNILPTNSAWLDQHCL
KNSEALAEVLSRYPNVKAILHGHIHQEVDAEWKGYRVLATPSTCIQFKPNCDEFTLDLLP
QGWRELSLFADGRIETEVKRLNSNAFLPDFQSKGY
>A0A2W1JK87|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acaryochloris thomasi RCC1774|TrEMBL
MKLHNRHKRKKRRKLWRKFVPVLSLLLLFAIALPIYGFKIEPYWLQVKTVPLTLPHLASE
FDGYRIVQLSDLHIVDEMPQRYLERVIRVTNRQQPDLIAITGDIVTDEPQRYASRIEAAL
QKLEAPTVSVMGNHDHWSDPTAVRQILKNSRVIDISNGVYDVYRKSAQLHIAGVDDVWAG
AADLDLVMAQLPDEGAAILLAHEPDFADTAVKTHRFDLELSGHAHGGQVTIPFVGPPVLP
PYGKRYPVGQYQIEDLIQYTNRGIGMVSPRARFGSRPEITVFQLSSAQAAE
>A0A4Q7DDX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cryobacterium sp. SO1|TrEMBL
MTGTTPTEGLKAVLPGTSVQMGQHPQASHLIAHLSDTHFLGTAADGSGRLLYDAVDTDST
VHRAMAQLEASGLAIDALVFTGDIADRGEPDAYRRVRDIVEASAERMGATVVWVMGNHDE
RSAFRTELLRTDGHDAPVDGVVDVNGLRVISLDTSVPGYHHGEVTPHQLAWLRDVLGRAS
EHGSLLALHHPPVPTALPLMTILELREQQALGDVLRGSDVRAILGGHLHYATTGLFAGIP
VSVAAATCYTIDAAAPPRQLTGLGGGQSMNLVHVYADQVVHSNVPLGSFDVVTRFDPAYL
DRMEALSPADRLAAFSRHTTSAAR
>A0A6I6H2L4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas alkylphenolica|TrEMBL
MPQQSIPHSDASLYLVQLTDSHLFADGQGTLLGMNTRDSLQRVVERVREEQPRIDLLLAT
GDLSQDGSEASYEYFRDLTASLGAPARWLAGNHDEPVPMERVAQGSDLLKPLVDIGNWRI
LMLNSAVPGSVPGVLDERQLALLEQSLKEAPERHHLICFHHQPVPIGCAWMAPIGLRNAD
ALFALLNGYPQARALLWGHVHQEWDERRDGLRLLASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLHDDGSIDTGVSRVTDFVFTVDYEGDGY
>A0A657I2X3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Crewe|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDVDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A679ITU1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium bullatum|TrEMBL
MIDRPALTRRETLAGAAVLALAPSAARSSERATGSVYEVVPGGRAGIADIAVSNGRDVVR
TDGQGRYALDVSDGDIVFVVKPAGFALPCDENNIPRFSYIHQPQGTPPNLRLRYRGIDPT
GPLPPSIDFTLTREPEPDAFDVILFTDPQPESPVELGHVRDTAVTRVLGTKAAFGMTTGD
ILFDDLSFYGRSNRIIGRIGIPWFHIGGNHDLNFEAPDARYSRETYKRVYGAPYYAFHHG
KALFLMLDTVHYLGAASGNGDGVGRYEGRIGERQLTFIANMLSMTPKETLVVIAMHIPLF
TDLNQADPRQNVMDRERLLDLLGDRPVLSLAGHTHTTEHHYPRADATGSHHHHVLTAVSG
SWWSGPSARTGIPSADSRDGTPNGFHVLSIDGAAYTTRYRPAQGEPEERMRIVLESQYRG
GAGEVLRDYRPMQTLRSPVPRESVGATNLVVNVFDGGPRTSVRYRIDDGPTLEMVRTRRP
DPFVAEVFLRYPEAKKPWVKAEPSSHIWVARLGGDIPAGSHRITVEVRDEYGRPYSSAMV
LEVTGEDGPSRG
>W0Q7M1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mannheimia sp. USDA-ARS-USMARC-1261|TrEMBL
MSEQFELPKNGTVRLLQITDPHLFSHTEETLLNVKTVKSFSAVIEQIQKQIEQTQQGFDL
VLSTGDLIQDHNIAGYHYFAQLTEPLKTPIVWLEGNHDVQPNMTEILGEYSHILPHKQIL
IGEKWQLLLLNTQVAGMPYGELCYHQLKWLEAKLNEYPERFTLIALHHNILPTNSAWLDQ
HSLKNSDELAKILQPFNNIKGIVHGHIHQQVDDIWNGIPIYATPSTCIQFKPNCDQFTLD
LLPQGWREIILHENGAIETTVKRLNSNDFLPNLNALGY
>A0A5B0K7A9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudocitrobacter sp. 73|TrEMBL
MESLLNLPLAGGASVRLLQITDTHLFAKKSETLLGVNTWDSYHAVLEAITASQREVDLVV
ATGDLAQDHTSAAYQHFAEGIARFSAPCVWLPGNHDFQPAMYSTLQDAGISPAKRVMVGE
HWQILLLDSQVFGVPHGELSEFQLEWLEKRLEEAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAASLDNVLVNFPKVKNLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHADGTLTTEVCRLAGSEFHPDTASEGY
>A0A287CYW4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ictidomys tridecemlineatus|TrEMBL
MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRNIQLPPLAFRQLEQAD
LKSESENIPRPTSLPLKILPLIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQAN
FVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFA
ALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLKELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPM
SQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLT
VIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTP
ALEAVFTDLEILAAIFASAIQDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKXXKKNVLATDMSKHMNLLADLKTMVETKKVTSSGVLL
LDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCD
KHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPD
DQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVGEEESQPEAPVIDDCSPDT
>A0A453Z203|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles merus|TrEMBL
MEESVFAEQTTRLVSDLKFPNLLPPNPVIKILIAFCKNDPVFEALVNASHRLSLEPTFVK
SAESAIDAFQNPSSGGHHIIIVDARYPRTIEAEALGRSIRNSKGSQHTTMVAVVKKSVFE
KDDTAVISLLDVGYNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQALYTALHRSRE
AVIITDDTLRAQYANRASERVLNMKLDEIVGRSLSDLVTADISNILSHTSRYKDYDGYLT
TRRKSQESSQIHVRAVPVSCIGRNPTHLVLILESSSSALVSTNAIGEALQTLPQGKEVPR
GSLHSIRRGSFDVRSIASDGLRRTSLAKLSSLPLEAPITKVLSLLAQVQENCSLDEAKLL
DRVMEFLKREGLYSPQMKEIRTEDPVATDLIGALLTQGPTNILSSRRSSNDSIIRGGGRP
STGSIVFNKTKESSQLSDLLQTALDWDFEIFKLEDLTEKRPLVCLGLELFRRFDVYNTFN
CDEMTFKLWLIEMEKHYHSENTYHNSTHAADVMQATAVYLQQLSNRELKIMDRMDEATAL
IAAATHDIDHPGRSSAFLCNSDNTLALLYNDICVLESHHAATTFRLTLGDDKINIFKHLD
RDMYKLARSIIVDMILATEMTRHFEHLAKFVSVFGTDVESKDPLPPDNDDNQILVRRMLI
KCADVSNPTRPLKFCVEWARRIAEEYFMQTDEEKRKNLPIVMPMFDRTTCSISKSQIGFI
EYIIHDMMDAWNSFIEMPEIIRYMEFNYSQWKLFEEQGINTLSDIKRKQMSLTEDTASSI
SLEEKF
>A0A399FC62|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Meiothermus granaticius NBRC 107808|TrEMBL
MRVFAIADLHLSRGFPKPMNVFGPLWEGHPQAVFSRWREVVQEDDLVIVAGDISWAMRLK
EAMLDLEDLQQLPGTKVLLRGNHDYWWPSITRLRQILPAKMHALQNDSLLIGDLAIAGSR
GWDTPGSYGFGEEDQKIYRRELERLELSLASTRSLAYQHLVVALHYPPYSASGGPTGFTE
LIDAYRPSCVVYGHLHGADPARLPQDWNGIPLHFVSADVLRFRPKLILEGAS
>A0A399F9W9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Meiothermus granaticius NBRC 107808|TrEMBL
MAQSYPFRINRQQRPLSGLERPLRMVQLSDLHYGPFIHATSVARWVDAALQQAPDVIVIT
GDLVDAGSRIRWRASANNPLTPDLDLLIAELGRLQAPLGVYSIWGNHDNWAPSAKRYLQE
RLPEVGIRILNNQGQLLRPDFYLGGVDDFWDGHADVFAALGNYKPGPACVMLAHNPDYLD
FFFRRPVDLGICGHTHGGQVFLPHYGAPWTPSWYGATYLGGWYPPGQSPTLPPVLGFVSK
GLGMTAVPLRLNAPAEVVVLDLQPLAR
>A0A140D6X8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurella multocida|TrEMBL
MFKIIQITDPHLFKDEHGELLGINTFQSFSQVLHEIKASRFDYDLVLATGDLVQDSSREG
YLHFCEQVKSLEKTVFWIPGNHDFQPKMFEILNQDQGNLNPKKHILLGKSWQILMLDSQV
FGVPHGELSQYQIDWLVAKLKDHPERYTLIVLHHHILPTHSTWLDQHNLRNAHELAYALA
PFDKVKGILHGHIHQEMDANWQGYRVMATPATCIQFKPDHNTFTLDSVQPGWRELELHSD
GRIETRVKRIQDKTFFPNMHEDGY
>A0A2N5EJH9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chimaeribacter arupi|TrEMBL
MESLFTLPVAGDARVRILQITDTHLFAGEHETLLGVNTLRSYHAVLDAIAAQQRPVDIIA
ATGDLAQDHSLAAYRHFAAGITRFPVPCLWLPGNHDFQPAMVDALAAAGIAPSKQALLGD
HWQMILLDTQVSGVPHGELSEYQLAWLARCLAAYPDRYTLLMLHHHPLPSGCTWLDQHSL
RNAHELAALLANYPKVTTLLCGHIHQEMDEPWHGRRLLATPSTCVQFKPHCTNFTIDSAA
PGWRYLDLFPDGRLETEVHRLDTHEFSPDMDSDGY
>A0A7J7XDC3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Myotis myotis|TrEMBL
MPLVDFFCETCSKPWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQNEVE
IPSPMMRDGERAPRPRPSQQPPPAEPQFQPMSQITGVKKMTHSSSLTDASIPRFGVKTDQ
EELLAQVGGGPAGAGLERGRVSWGRTGCWVSLRCGLGWMGPQSIPMKPFVNSHGVK
>V9ZX24|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas hydrophila 4AK4|TrEMBL
MRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQANGHPFDLILATGDLSQDHSPESY
QRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGDHWQVILLDTQVRGKP
HGVLGDHQLAALDSALRQHPERHALIALHHQAVPVGCAWLDQHNLKNADDLFAVLARHPQ
QKTILFGHVHQEFDEVHQGVRLIASPSTCIQFKPLSDGFALDESGPGWRYLTLHPDGRIA
SQVWRLPVGQFVPDPNATGY
>A0A2G8E597|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia sp. OLSSP12|TrEMBL
MDSLLKLSAASGAAVRILQLTDTHLFAGKHETLLGVNTWASYEAVLDAIIARSTHYDLII
ASGDLAQDHSPQAYQNFVEGIRRLPAPCVWLPGNHDFQPAMYATLAAAKIEQAKQVLLGE
NWQLLLLDSQVFGVPHGELSDYQLDWLENALSRYPQRHTLVVLHHHPMASGCSWLDQHSL
RNSTMLDAVLHNYPLAKTVLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCTSFTIDSEP
PGWRWLELYDDGQLRTTIERLTCRDFVPDLDAEGY
>A0A5P1DQ21|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. JG-B|TrEMBL
MPNPFPPAADESVLLVQLSDSHLFAEADGKLLGMETRDSLRRVIDQVLQEQPRIDLVLAT
GDLSQDGSVESYEAFRDLTASIPAAARWFPGNHDEVPVMRDVCAGTAELEPIVDFPHWRL
VLLDSTIAGAVPGHFPDEQLAFLESALEGAGERHVLVSFHHHPVPIGCTWMDPIGVRNAD
SLFAVLDRYPQVRALLWGHVHQEFDQIRNGVRLLASPSTCVQFAPGSEDFCVGSEAPGYR
WLRLIRDGSIETGVSRVIGITFEVDYSIKGY
>A0A2X2J5P2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia quinivorans|TrEMBL
MESLFKPTVASGARVRILQITDTHLFAGENETLLGINTYRSYHAVLDAILAQQRDFDLVV
ATGDLAQDHSLAAYRHFAEGIARLPAPCVWLPGNHDFQPAMVDALADAGIAPSKQVLVGD
HWQVLLLDSQVFGVPYGELSDYQLEWMERCLQAYPERYTLMLLHHHPLPSGCTWLDQHSL
RNPHMLGAVLLRYPKVNTLLCGHIHQELDLEWQGRRLLASPSTCVQFKPHCTNFTIDEVS
PGWRYIDLLPDGRVETQVFRLENDDFRPDMDSEGY
>A0A8B5QLN7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. wls712|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A7X8YG52|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio agarilyticus|TrEMBL
MSALESVRLLQITDTHLFAAEEGSLLSVNTLASFTAVVDAIVRQQVGFDAIIATGDISQD
HTDSSYQRFAKGIEPLQKPCFWLPGNHDYKPGMHSIFPSAQIHAPTTVMLGQHWQMVLLD
SQVAGVPHGYLEQTQLDQLEQALSENRERYTLVLLHHPPRLVGSQWLDQHTLKEAEAFWQ
LVAQFDHVRGVVCGHVHQELDCVYQGVRVLATPSTCVQFKPNSDDFALDRNAPGWRELTL
QPNGVIETQVKRLQPNHFLPDFTSAGY
>A0A3Q2KJZ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Equus caballus|TrEMBL
MNVEINYGSRMSITEAHCCGLTGREHPQRLTFSSTSLQSFSWGAGRSLEKRFDVENGPSP
GRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDD
LIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVHLQGPRMKDRLGVHK
DGAL
>A0A7W4GF35|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. SG44-2|TrEMBL
MLKDAVHYSVAENEPVRLVQVTDPHLFADPEGQLLGVNTAQSLQAVLNTFIATQYPANIL
LATGDISQDYSPESYQHFVQKIEMLDLPCHYLPGNHDDPRLMSLRMQGEKVFGQQRIIIG
NWLILMLDSTVRGKPGGYMGEQQFALIEAAIKATPDKHVLLVMHHNPILMQCAWLDQHCM
MNGEDFLQRTSRYPQVKGVLWGHVHQQVDNIHRGPHGPIPLMATPSTCIQFKPLSSYFAL
DHRQPGYRLLELAGDGSIRTNVYRVPGNRFAPDNEASGY
>A0A0G4QC86|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteus penneri|TrEMBL
MESQLELSVKHKNTVRILQITDTHLFANVEDTLLGINTYRSYHAVLNAIREQGLDVDLIV
ATGDLVQDQTFEAYQHFADGIATLTPPCVWLPGNHDYQPAMIDALNQAGVLSAKQVLIGD
NWQMLLLDSQIQGVPHGELSDCQLDWLTRCLESQKHRDTIILLHHHPMPSGCTWLDQHSL
RNSQELAERLREHSQVKMMLCGHIHQEMDEMWNGIRLLATPSTCIQFRPHCTNFTLDTVS
PGWRYLEMSLLSDEKGRIETQVYRLEGTEFCPDLDSDGY
>A0A418SLI2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudooceanicola algae|TrEMBL
MTRIAIVTDIHHGAPSHTKRGDTALELLADFTRWANAEGPDMILDLGDRISDIDAATDDR
LEREVAQALSHLDAPIHHICGNHDRDHLSVADNETILGSPLQSEVIDLGDWQLALWRADA
RIHRDTATPGFDLPEADLLWLSRMAQRADKPTLVASHVPVSGHSQIGNYYFQRNASVSTY
PQADRARQALAQARVPVACIAGHVHWNTVTTVDGIPHMTQQSLTESFTTGGEPARAWGMV
TLGETLHWQVHGDDPFEARLSPGRRWTPPLAPFLQSLAAE
>A0A5A5RYI5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcystis aeruginosa NIES-2521|TrEMBL
MNFRFAILSDPHIALPTTILNHSNRFHLVEVSIPALKIVLDHLITLNLDFLLIAGDLTQD
GEPENHRWLADCLATLPFPVYVVPGNHDVLSLTATENQIGLGDFPFYYQQFGYSDPEQIY
YQKEILPGVQLIGLNSNQFDEQGKQIGSLDAEQLHWLKQILPSLKNDLVMVMIHHNVIEH
LPGQSNHELGKRYMLANAGELLDILQENGVKLLITGHLHVQDLAFSRGIYEITTGSLVSY
PHPYRVLEYSENTGELAIESFHLQNIPGWENLPAISRQWLGDRSYPFMMRLLTCHPLNLP
VSLAEELAPKLRNFWADVAKGDTIFDFSDFPPLVRRYFYAFSAIDPLGNPHFIDNQAVIS
FKHQFSYQRSDLLVEFRE
>A0A2T0AZ46|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clostridium thermopalmarium DSM 5974|TrEMBL
MGEKNLKSKRIIILGDSKGKDDGINKKILNKIFKQIKELKTQPEYIIHLGDSVAGSSDVR
IFKYQIKEFHKLIEQYYPINRLLPVLGNHEVNNKPKDFQGEEAFEECYSSIDVDNYLKGY
HKTVYYKDFDNVRCIFLNSFHYGELFRITGRQLEWFRKVTKDLIPFKIVFVHLPIYPTGA
HLTTCMDAYIEDRNTFLKALEESNVSLVFCGHEHNYSRRLIGFNDKKIMQIITGGAGEKL
RNSYKDKKDVIVTPKPIYHYVILDIEEDNIRVRAVSLRKKVFDDFSVGIGDGSQIFI
>U6D644|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Neovison vison|TrEMBL
GGNGLQQGEEDQIAEIICLCPQCPHHHCPHLPLQFKRMLNRELTHLSETSRSGNQVSEYI
SQTFLDQQTEMELPRVTPMESPRPMSQISSLRGLPHRASLSAATVPRFGVQTDQEGQLAK
ELEDTNKWGLDVFKVAELSGNRPLTTVMFSIFQERDLLKTFQIPADTLVTYLLTLESHYH
ADVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLI
>A0A760F9B6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGLASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>D7XRY1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli MS 84-1|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>U1R1L0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aggregatibacter sp. oral taxon 458 str. W10330|TrEMBL
MLNTYQYHAQQEVFRIVQITDPHLFKDINGELLGINTQASFSQVLTEIQQAHYAYDLVLA
TGDLVQDGSDEGYLRFCDNVKSLEKMVFWIPGNHDFQPKMVEHLTQGNVNAGKHLLLGEH
WQILLLDSQVQGVPHGQLEPETLAWLKTKLEAYPQRYALVVLHHHLLSTGSAWLDQHNLR
NPHELASVLAPFPRVKALLYGHIHQQADSTWHGYRVMASPSTCVQFKPDCNSFTLDTLQP
GWREIELYADGRIETRVKRIQQASFLPNFQESGY
>A0A6L5BX31|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas frederiksbergensis|TrEMBL
MPSVSTLTTADSALLVQISDSHLFAEADGTLLGMNTRDSLQKVIELVRRQQPQIDLIVAS
GDISQDGTLESYQQFRNLTRQLDAPARWIPGNHDEPMVMAEAAVQSALLESVVDLANWRI
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
GLFAVLDRFPQVRAVLWGHVHQEFDQDRNGVRLMASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGVLETGVERVTGFDFTVDYGSDGY
>A0A011LW31|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mannheimia granulomatis|TrEMBL
MNESLKLDKKGAIRLLQITDPHLLSTPQETLLEVKTVESFAAVINQINAQVAETSQPFDL
VLATGDLIQDHHIAGYHHFAKITAKLNTSIVWLEGNHDTQPNMGEILATYPHISPHRHIL
VGDYWQILMLNTQVIGRPYGELSSEQLVWLEETLNQFPERFSLIAQHHNILPTNSAWLDQ
HSLKNADKLAEILTKFKKVKGIVHGHIHQQVDSIWKDIPIFATPSTCIQFKPNCDQFTLD
TLPQGWREFYLHEDGEIETVVKRLNSNDFLPNLNSKGY
>A0A2H9U7L9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas cavernicola|TrEMBL
METKLPQAQDGSVRLLQITDTHLFASADGQLLAVRTADSLAAVLAQVQINDHPYDLILAT
GDLSQDHSAESYQRFASMMLPLARSIYWLPGNHDDAPLMTASMHAVGISEAKQLVGDHWQ
VLLLDTQVRGKPHGVLGDHQLAALDQALRQYPDRHVLIALHHQAVPVGCAWLDQHNLKNA
DELFAVLARHPQQKTILFGHVHQEFDEVHQGVRLIASPSTCIQFKPLCDGFTLDESGPGW
RYLTLHPDGRIASEVWRLPVGQFVPDPNATGY
>A0A399V0X0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nakamurella silvestris|TrEMBL
MQSKILQQTDKDKVIIQITDTHLMDKPDAKFVGINPEESFHAVMEDVQQRFPNADLILHT
GDLAQAAYPETYARYLNYMRGFGIDFYHIPGNHDNLSFFPFHVPEPEPTVIELDQWCIIL
LNSTVSGRTDGKIQPEQLVRLKQRLEQLRDKFVIVACHHNPFEMHSKWLDQHKLKNADEL
KAVLEPFNNIKLLLHGHVHQESYNEWNGIQFISTPATCVQFKPLSQEFSFDPIAPGYRCL
HLKANGEFETYVHRLDH
>A0A5M9J764|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas extremaustralis|TrEMBL
MKRSFLVAQISDLHLKAGQRLTYGVVDTLGALRRAVDHLNASHPRPDIVVVSGDLVDFGR
ADEYAVLHPELARLHMPCYLVPGNHDTRGPLLDAFRDHAYLPLSAEQPLDWVVDEHPLRL
IGLDSTIPGGHGGQLLDSQLQWLDEQLARRPDTPTLLILHHPPFVSGIGHMDREPFINAA
ALEHVVARHPQVERLLCGHLHRPMQRRFGGSLSCVCPGTSHQIVLDLQDAAPAHFNLEPA
GYLLHRWDAQHGLISHNGVFGDYPGPYPFYDAHGLID
>O43862|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|TrEMBL
MKEQPSCAGTGHPSMAGYGRMAPFELASGPVKRLRTESPFPCLFAEEAYQKLASETLEEL
DWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEV
EIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKW
GLHVFRIAELSGNRPLTVIMHTIFQ
>A0A7Y4EKC9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. 03-59-1|TrEMBL
MKLSSSSESALGSIKLLQITDTHLFAPADGSLLSVNTFDSFQAVVRDIQAKAFKFDAILA
TGDISQDHSQESYQKFESGIECLQKPCFWLPGNHDYKPNMSSVLPSPQIQCVEHVLLGDR
WQMIMLDSQVVGVPHGRLSDQQLALLDEQLTLHSDRHTLVLLHHHPILVGSEWLDQHTLK
DAEQFWNVVDQHQNVRGVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSNDFALDSQSP
GWRELELHLDGSIETQVNRLSDGRFLPDFNSDGY
>A0A6P8SPM3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gymnodraco acuticeps|TrEMBL
MASNKFKRMLNRELSHLSEMSRSGNQVSEYISSTFMDKQNEVEIPSPTLKDKSMSHITGV
RKLCHSSSLSSSSMPRFGVNTDHEDELAKELEDLDKWSFNIFSLAEFSNNRPLSCIMYTI
FQERELLKTFRIPVDTFVTYVMTLEDHYHGNIPYHNSLHAADVTQSTHVLLSTPALDAVF
TDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLHQEH
CDIFQNLNKRQRQSLRKLVIDLVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDHYNE
RIQVLRNMVHCADLSNPTKALPLYRQWTERIMEEFFRQGDKERERGMEISAMCDKHTASV
EKSQVGFIDYIVHPLWETWADLVHPDAQELLDTLEENREWYLSTMPQSPSPPP
>O77823|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sus scrofa|TrEMBL
PWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVDIPSPTMKDHEKQQ
APRQRPSQQPPPPGPQFQPMSQITGVKKLMHSSSLNEDSSIPRFGVKTDQEELLAQEL
>A0A8C0R6V6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Canis lupus dingo|TrEMBL
IYDSHRERERGRDTGRGRSSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFL
YRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPS
KRSPMCNQPSINKATITGKEDLVASSSSVWKKNMSSNIRLTNFILQFCSFKEIGPCSLST
>A0A7X6WVY2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alcaligenaceae bacterium|TrEMBL
MPEHLSEAVVIAQLTDPHLFADPAATLLGINTNDNLQGVLEHLQRHSRGPEHLLATGDLT
QDGSPEGYARFLRMARQLQLPVHALPGNHDDRAVFHHVLGSVAAPVVELLHWRIVLLDST
IPGESGGHLGEDQLALLDALAQADDPRHVLLAMHHSPISLRSAWLDTMVIDNSAAFFAQL
ARYPQVRALLWGHVHQAYDGSLPLPHHGGSRTLRLMATPATCFQFRPGSQDFSLDTVAPG
YRWLTLHADGTIETEVVRVPDLTQTPDLSSQGY
>A0A6S6ZJK9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter pestifer|TrEMBL
MTRILQFSDTHFGTERKPVVEAALDLARSLNPDLVVLSGDITQRARRGQFAAARKFIERL
SLPVLAVPGNHDIPLFNVFARALNPYGNYKRALGAVLEPVFETAGLLAIGVNTTRPRRRK
DGEISDTQIARVAQRLRQARPGQLRIVVAHHPVRAKVESDLSNLLIGRERALAAWAQAGV
DLILGGHIHLPYVLPLTAAGQSAGWIVQAGTTCSHRVRGSVPNSVNVITHEGAGGQPACH
VERWDYAEGTHTFAPVDNTLVTLP
>A0A0S7GTW6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
MRRNNSRLFNVTERHWDSSEPASSVELLQDPDVRYAVKRVFSGNVQLPRLSCRPSAQERA
QDGAPPEPAAPPTRSIRHSRSLGTLTSCFDVENGLSVPRNPLDAQSSSSSGLVLQVNYPH
SQRRESFLYRSDSDFDLSPKGPSRNLSSTSDLHSEDMIVTPFAQVLASLRTVRSNFALIT
GQQDRAASKTRSSGSNPPSMCKTSLAEEPHQQLAIETLDELDWCLDQLDTLKTRNSVSEM
ASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKPDDMDIMSPTTKEKDKKKHPMSQ
ISGVKKATHSLVPSTIPRFGVNVSQEEFLAKELEDIDRWGLDIFKVAEYSGKRPLTVTMY
TIFQERDLLKTFKIPADHFINFTMTLEDHYRSDVAYHNNIHAADVVQSTHVLLSTPALEA
VFTDLENHHLAVGFKLLQEDNCDILQNLSKKQRQSLRKMVIDMVLATDMSKHMNLLADLK
TMVETKKVTNLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFTQG
DREREKGMEISPMCD
>A0A0S7GV78|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
KVTLQNSPFASFTRLSCPVQRHWDSSEPASSVELLQDPDVRYAVKRVFSGNVQLPRLSCR
PSAQERAQDGAPPEPAAPPTRSIRHSRSLGTLTSCFDVENGLSVPRNPLDAQSSSSSGLV
LQVNYPHSQRRESFLYRSDSDFDLSPKGPSRNLSSTSDLHSEDMIVTPFAQVLASLRTVR
SNFALITGQQDRAASKTRSSGSNPPSMCKTSLAEEPHQQLAIETLDELDWCLDQLDTLKT
RNSVSEMASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKPDDMDIMSPTTKEKDK
KKHPMSQISGVKKATHSLVPSTIPRFGVNVSQEEFLAKELEDIDRWGLDIFKVAEYSGKR
PLTVTMYTIFQERDLLKTFKIPADHFINFTMTLEDHYRSDVAYHNNIHAADVVQSTHVLL
STPALEAVFTDLENHHLAVGFKLLQEDNCDILQNLSKKQRQSLRKMVIDMVTPTSQPAQF
REFRLSGVF
>F9T647|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio tubiashii ATCC 19109|TrEMBL
MKVTSSSSNSDSIKLLQITDTHLFEPVDGSLLSVNTLDSFNAVVAAIVEENQSFDAVIST
GDISQDHTAESYQRFERGIAPLKNTCFWLPGNHDFKPSMSSVLPSTQIKQVEHVLLGEHW
QMVLLDSQVVGVPHGRLSDQQLALLEDKLSQYPERNTLVLLHHHPILVGSRWLDQHTLKD
AHHFWEVVEKHSNVKAVLCGHVHQDMNVLHQGVRVMATPSTCVQFKPNSDDFALDTLSPG
WRELELHSDGQLTTQVKRLPYGSFQPDFNSAGY
>A0A712CNQ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica I|TrEMBL
PHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSLRNAGELDSVLANFP
RVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIAPGWRTLELQANGVL
ETEVHRLQDTRFRPDTASEGY
>A0A2R8C3Z9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Falsiruegeria mediterranea M17|TrEMBL
MKLIHISDIHLTLPGEEMGGLDPHSRFARALADVGENHPDAARIIITGDLTHWGEEGAYE
ALKAAVTGAPVPVRLMIGNHDDRATFRKVFADHSIDANGFVNHAETLDGVRLIFLDSVGD
KTHAGHFCAKRRDWLRAELEECDRSRIFLHHNPMEIGLPAEDKIALVAEDRPGFRALLEE
FADRIDYLHFGHVHAPIHGRYAGVQFASVPSTGNQSLPDLSEAEFLQGAPMEPGYFVLLI
NGDDTIIHQVPFNWTGPIYTAGTDWDDWVKPDVAAAE
>A0A827HIM6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYLHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGVSPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCRWLDQHSL
RNAGELDNVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A5I4X2C8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Durban|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A352MSN1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp|TrEMBL
MESLLNLNLAGEASIRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIRAEQRHCDLIV
ATGDLAQDHSAAAYQHFAEGIASFDVPCVWLPGNHDFQPAMYSALQEAGISGAKRVFAGD
SWQILLLDSQVFGVPHGELSEFQLEWLEKKLAEVPERYTLLLLHHHPLPAGCGWLDQHSL
RNSQELDNVLVRYPRVRHLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELNADGTLHTEVSRLQTSRFRPDTASEGY
>A0A7Y8D1J9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MPHPDPSQAPVCVVQLTDAHLFADPAGTLLGLRTRDSLRHVIAQVRREQPCIDLLLCTGD
LSQDGSAASYQAFRDLTGDFAVPARWLPGNHDEARVMAEVAPELVQAVTDIGAWRIIMLN
SAVQGATHGLLEPSQLSLLDDALLSAGGRHCLICCHHQPVDIGCAWIAPIGLRNADELLR
RLEGYPQVKALLWGHIHQEWDELRGGLRLLATPSTCIQFAARSEDFKVSEEQPGYRWLRL
HADGRLETGVQRATDFEVKLDFDSPGY
>A0A4D6XK05|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MPHPDPLQAPVHVVQLTDAHLFGDAAGTLLGLNTRDSLRHVIAQVRREQPRIDLLLCTGD
LSQDGSVASYEAFRQLTGEIQAPTRWLPGNHDEARVMAEVAPELVQTVTDIGAWRVVMLD
SSVLGATHGLLEPDQLALLDQALVSAAGRHCLVCCHHQPVDIGCAWIAPIGLRNADDLLQ
RLKGYPQVKALLWGHIHQAWDEQRDGIRYLATPSTCIQFAPGSEDFKVSEELPGYRWLRL
HGDGRLETGVERARDFEVRLDFDSPGY
>A0A0T9U627|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia aleksiciae|TrEMBL
MESLFKLPMASGAKVRILQITDTHLFAGEHETLLGVNTSHSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGIARLPAPCLWLPGNHDFQPAMVDALADAGIAPSKQVLVGD
NWQILLLDSQVFGVPYGELSDYQLAWMERCLVAHPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAILIRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPNGILETEVRRLASDEFCPDMDADGY
>A0A334NVJ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter nosocomialis|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIQQILKQHPEADAIIHT
GDLAQAPTPITYKRYINFMQTLGLPFFHTLGNHDNVDHFPLHNENHQEPVVVGLGNWRII
MLNSAVKGKVDGHLSLEQLENLENLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFKNVKALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSNDFALDHNAPGYRY
IRLNNDGTFETKVFRLENFETHINTDISGY
>A0A2K1DVD1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio agarivorans|TrEMBL
MHLSSDSIKLLQITDTHLFATDEGNLLSVKTADSFNAVVKAILCQQVPFEYILATGDISQ
DHSTASYLRFAQAIAPLKKTCFWLPGNHDFKPNMRDVFPSAQIKAEEHVLLGEHWQLILL
DSQVVGVPHGQLSQEQLVLLDTKLALFPDRYALILLHHHPLLVGSAWLDQHNLKGADKFW
QVIRQHNNVKGIVCGHVHQDMNVMDNGIRVMATPSTCVQFKPNSDDFALDVTSPGWRELE
LHANGDITTEVKRLPDGLYQPDFTSSGY
>A0A0T9TLE0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia aldovae|TrEMBL
MESLFKLPMASGAKVRILQITDTHLFAGEHETLLGVNTSRSYRAVLEAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGIARLSAPCVWLPGNHDFQPAMVDALADAGIAPSKQVLVGE
NWQILLLDSQVFGVPYGELSDYQLEWMERCLVAHPERYTLILLHHHPMPSGCTWLDQHSL
RNAHVLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLSDGTLETDVRRLASDEFCPDMDSDGY
>A0A3M6P5Q4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aggregatibacter aphrophilus|TrEMBL
MLNTYQYNTQQEVFRIVQITDPHLFKDTNGELLGINTQASFSQVLTEIQQQQYAYDLVLA
TGDLVQDSSDEGYLHFCEGVKAFEKMVFWIPGNHDFQPKMFDLLTKDNISAKKHILLGER
WQILLLDSQISGVPHGQLSEYQLDWLLAKLKEYPQRYSLVVLHHHILSTHSAWLDQHNLR
NAHELAYVLAPFSNVKGILYGHIHQQVDGEWHGYKVMATPSTGIQFKPDSNTFALDTVQP
GWREIELHADGRIETRVKRIQHKTFLPNLQEEGY
>A0A5R9QYZ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas nicosulfuronedens|TrEMBL
MPTQPTASDSVLVVQLSDSHLFAQENGRLLGMDTADSLTQVVRLVGEEQPVIDLVLATGD
LSQDGSVESYQRFRAITAPIDAATRWFPGNHDEMEPMREATAGTDLLDPVIDLGAWRVIL
LDSTIPGAVPGQMTVEQIQLLECAIQAAPDKHLLISFHHHPISIGSQWMDRIGIYNPERL
FAVIDRYPNVRCLLWGHVHQEIDRMRGDVRLLASPSTCVQFTPGSEDFCVDSPAPGYRWL
RLMADGEVQTGVSRVTDIEFEVDYSIKGY
>A0A0C3I2V5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio mytili|TrEMBL
MLQSSSSDSIKLLQITDTHLFASDEGSLLSVKTADSFNAVVDDILRRKVEFDFILATGDI
SQDHSAQSYQRFADGIMPLRKDCFWLPGNHDYKPNMGSVLPSTQIQASEHVLLGDHWQLI
LLDSQVVGVPHGRLSDQQLALLEAKLSEYPQRHTLVLLHHHPLLVGSAWLDQHTLKDPDE
FWQVVERFSNVKAVLCGHVHQNMDVLHNGVRVMATPSTCVQFKPNSDDFALDCKSPGWRE
LELHATGDITTNVSRLPDGLFQPDFSSNGY
>A0A564RZQ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bifidobacterium longum subsp. infantis|TrEMBL
MKRRYAVPVVSAVVMVLASVLAAPSAHAEQSATWDLPRDKDVVARFGFGSDIHVGRDSGK
YGSAVDKLKNALSAYRQSGVDAVGFSGDLTDSGQVGQYQTLMDTLNTGTDDSEQVILAMG
NHETLDAGVSDSPQRFKKYTGQDMNKLVEVNGVDVITMGPQNEDDDYRADYDFLKTTLDR
ITSRANYDPNRPIFVLTHHGVQNTAYVTNEWYGEYGAGTDHDLVKLMQQYPQIIQVSGHS
HATLEDARSIDQSLGYTSIQDGTIGAYFENESGKVDPITGTAATRPADSELASQGLLVDV
YRDGTVKVHRMNFATGTWIYPDEPWTITADGAKANVYGKNRPSTPAMFPDGASVGFDTAK
TTGNSAAVTFPAAKPADGTNNNMIHSYRITMTPKNGGETVSKSVFNDYYYAKAGVGAAGA
VPTQKSRWSVTVKGLTPQTEYTATVEALTSFEEENGAAGAVIASSQTSVTTNEAPAPSPM
FDVDFGSGSADDYYAHQSVKQGGVSAIEDNAELGQQVLHVRGGDGGYRYTMEDEDYNAIA
NGFTTDVVFSIADVQKDQCVFSNQQNAGFGFEVENGKLEFWLNAGSGRAKPAVAIQPDTW
YHASAVYDGNTVTLYLNGEKVDSASAKSGLVIPSNGAKYFFIGADTSGSGAPEYQMKEGY
VALARISSQVFSDDEVAASYTNAMGDGPAAKQTVRQALTAAKRVVEAGQGNYSDATWSAF
ADAYTTALVRVEDFRAAPADLNAAAVALRSAQQALQETNSGDDGNGGNGGDGGSDAGGQD
ANQPGGSHDSDSGADKSSASQEANAADRLSATGVNTAGLLAVTLVLVGAALTLKVVRRR
>A0A077PIT0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus bovienii str. kraussei Becker Underwood|TrEMBL
MESLLKVPVAEGATARILQITDTHLFASKGDALLGINTYRSYHAVLDAILEQSIDIDLIV
ATGDLVQDQTIGAYQNFAEGIARLPVPCVWLPGNHDYQPAMVDVLAAAGISPSKQILIGQ
HWQLVMLDSQVQGVPHGELTDYQLEWLQKCLDEHNDRNTIVMLHHHPVPSGCTWLDQHSL
RNAPALAEFLKDKRQVKAILCGHIHQELDKMWNSIRVMATPSTCMQFKPHCTNFMLDTVA
PGWRYLELSVAGNREARLQTQVHRLKSNEFCPDLDSDGY
>A0A5B0WW90|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudohalioglobus sp. NY5|TrEMBL
MGNLSSSAPLCRIQPAGDSVHLVQLTDTHLCAQRGGTLLDMDTDRSLQLVIRQVLREREV
IDGVLCTGDLSDRGYLQAYQRLIEYLQAFDAESFWLPGNHDDREQMAAAIAGQAHLCGEV
RAANWQILMLNSQIPGEVGGELGAAEQERFESALQAAQEQGLYTLVCLHHQPVPVGSAWI
DQQQLADAEQFWQTVDRHPGVRGVLWGHVHQQIDTWRGDVALMASPSTCVQFAPGSEQFK
ADAQPPGYRWLELKADGGIGTGISRVMDASFNVDLESGGYL
>A0A5C7PW71|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cellvibrionales bacterium|TrEMBL
MIYQFDKAAPIHLLQITDCHIHNEPHRLLSGVNTYHSLTQVIDGVLTSNNQHADLALITG
DLTHEGDERAYRLLQEQLNRLPMPFFWLPGNHDHLAPMANTASSERQQAKQLLLQNWQIL
LLDTHVEDEVGGAVSQSELTWLATALREHPDKHAAIFMHHPLLPVGCAWLDPQRIANAEQ
VLTLFDNTPQLRVVCNGHVHQENDIQRLRYRLLSTPSTCIQFKRNSADYAEDDFPPGYRR
FVLHADGNFETEVVRVGELVRDANAPRGYDEFN
>A0A4V0ICC4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinobacillus porcinus|TrEMBL
MRNTYIDNTKAKVIRLVQITDPHLFKDENGELLGINTLASFNQVLREIQETDFDFNLILA
TGDIVQDSSDEGYLRFCERVNRLNKPVFWLPGNHDFQPKMQEYLNSEHGCVNSRKHLLLG
ETWQVLMLDSQVFGVPHGHLGQYQIDWVMSKLKEHPERYTLVVLHHHILSTNSAWLDQHN
LRNSEELAQTLAPFRNVKGILHGHIHQQMDAKWHGYQLMATPSTCVQFKPDSNHFALDTL
QPGWREIELHANGDIVTRVKRIQQAEFLPNMHEEGY
>A0A1B7K6J0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kluyvera georgiana ATCC 51603|TrEMBL
MESLLNLPLAGGASVRVLQITDTHLFAEKDETLLGVNTWESYHAVLQAIHASAREVDLVV
ATGDLAQDHSSAAYQHFAEGIASFTAPCVWLPGNHDFQPSMYSTLQDAGISPAKRVLVGE
HWQILLLDSQVFGVPHGELSDFQLEWLEKRLAEMPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGALDNVLVHYPRVKHLLCGHIHQELDVEWNGRRIMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHADGSLTTEVCRLAGSTFHPDTASEGY
>A0A094UCN2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium odoriferum|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKARQDAFDLIV
ATGDLAQDHTLQAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPGRFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSAVLDRYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A8C6JT59|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Melopsittacus undulatus|TrEMBL
YFQNSYVNDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMS
RNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKAS
LTGKN
>A0A7J0AL11|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MESVTDPLWMTNYELIYDQPELMVNWYPICGNHEYRGNTQAVIDYSGISRRWEMPARYYA
KTFEDDGTTVKVIFLDTTPLIDKYRKKTDTYPDAVNQDTEAQLQWLEKTLTEATEDWIVV
VGHHPIYAYTDKSESERTDMQKKVDTILRKHNVDMYICGHIHNYQHIRRPDSKIDYVVNT
SGSLTRTPQKIDGTVFCNDSPGFSVLTADKNNLRLNMLDKDGKTVHIVNRTK
>A0A5Q4ZEX7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia dioscoreae|TrEMBL
MLLAQISDLHIKRPGALAYRRVDTGAYLARCVAALNALEPRPDAVIMTGDLVDQGDPEQY
EHLKTLLAPLEIPYFMLVGNHDERAALRAAFPDRKELASGGEFVQYAVDLGALRLIALDS
MVPGQSAGTLCDARLAWLAAQLDAAQGKPTIVALHHPPFVCGIGHMDELRLDPAAADRLA
ALIARYPNVERVICGHVHRPMFVRFGGTIASAVPAPAHQVALDLREDAPSAFMMEPPAYA
LHHYDPATGIVTHHAYVDAADGPYPFYEPEGDLID
>A0A5J4FAE7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcystis aeruginosa NIES-4325|TrEMBL
MNFRFAILSDPHIALPTTILNHSNRFHLVEVSIPALKIVLDHLITLNLDFLLIAGDLTQD
GEPENHRWLADCLATLPFPVYVVPGNHDVLSLTATENQIGLADFPFYYQQFGYSHPEQIY
YQKEILPGVQLIGLNSNQFDDQGKQIGSLDAEQLHWLKQTLPALKNDLVIVMIHHNVIEH
LPGQSNHELGKRYMLANAVELLDILQENGVKLLITGHLHVQDLAFTRGIYEITTGSLVSY
PHPYRVLEYRENTVELAIESFHLQNIPGWENLPAISRQWLGDRSYPFMMRLLTCHPLNLP
VSLAEELAPKLRNFWADVAKGDTIFDFSDFPPLVRRYFYAFSAIDHLGNPHFIDNQAVIS
FQHQFSYQRSNQQTIN
>A0A7J0AQG5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MKSTLAIILTAMAASPLFGAIVRNIPDKDGMTIKGVVYCGDEPVQGAQVSDGVNVTRTDE
NGWYYLASAKECGHVFVCNPKGYKYLRKAKYPEFYKTVDTERPSAVEQADFELERDEATD
HTILFLADIQMCGRNEDIRQYEENAVGDINTSISNARKQGKDVYVITLGDQSYNTYWHSY
NIGIPEIHESMNLLDPDAIFNCMGNHDNNPKIAGDWAASTDYREQWGPTYYSFNIGEIHY
VVLDNIEFTNAECKNTFECNITTSVIKWLRKDLANVSKDTPIVVCMHAPLFYRPQCSKPN
VPDPTKYRYNYGSQFYNSVKGFKDVRVFTGHAHTNYTVSYLNMTEYNVGAIGGNLWWTGY
FVNGNSVCTDGSPGGYRVLDTSGKELKTYYKCIGFDNGYQFRCYDLNNCHITASRFAPSY
KNPADIDTWLANGYGFDSSDYNSDGTPKIPNRVLINVFAYDTNWKVEVLEDGKPLEVSRI
SGYDPFSMISDGCQRFEKTGHNNSGNPTQNSHLFLVTAKYATSPLSIKVTDQYGSVYTQV
MERPKGFSIDRYTPQNEQSAIFDIDSDSYSYPPEFYNINGIKVSRPENGLYVMRIGTKTK
KVFIR
>B4LLX8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila virilis|TrEMBL
MGCSPSTLPNSSSSAAAAPGGGGNGGNANLPLDGNEKDGSLLFCIKLRRSRMRRCSCGAV
TLQNQNGEGSTGSATCGDNMMCNQGLLNPLQTKNESDYEKLSTGKKDSIVTVAALGNFTH
SVVRRATGTGSTGTSGTSSSGGGGGSGRPGHRKSSLALALTPEDESMDVYQRNLMDLKYP
TVLPPNPQLKALLVFHKSDSICEVVTLACQRHQLDATLVKSKEEALETLHKSYATAQCYH
LIIIDARSTKGLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDALIALLDAGVNRCIA
ETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATE
RLLNMRLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMHVRVVPVA
CIGSAPTHLIFNFDIPGGGMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSL
AKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPI
ATDLIGALLTGPSVYSSRRSSNDSIIRTGNSTRAATIVPAKMKANPIIMELLEESLSWDF
DIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTH
AADVMQATGAFITQLANKDMVMDRMDEATALIAAAAHDVDHPGRSSAFLCNSNNPLAILY
NDLTVLESHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAK
FVSVFGSEVEPRELVQSEEETSILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYFMQT
DEEKQRHMPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWDGFLDMPQLITCMQINYSQ
WKKYDEQGVNTLADIMAKQPPVGNKTSNSKXHTAFRRIFSGLLKPLPAQAPATSTIGENE
MEDML
>A0A7Y3YMT3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio chagasii|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKLCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGES
WQMIMLDSQVVGVPHGRLSDQQLDLLEQKLAEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHSNVKAVLCGHVHQDMNREHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPNGQFLPDFEAAGY
>E8M7U6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sinaloensis DSM 21326|TrEMBL
MKVTSSSSDNSIKLLQITDTHLFEATDGSLLSVNTGESFKAVVQAIIDQECQYDAILATG
DISQDHSEASYQCFEQGIVPLLKPCFWLPGNHDYKPNMTSVIPSQQIQQVDHVLLGEAWQ
MIMLDSQVVGVPHGRLSDQQLDLLDEKLAEYADRHTLVLLHHNPIFVSSAWLDQHALKDA
DDFWQVLGKHSNVKAVLCGHVHQDMNVKHNGVQVMATPSTCVQFKPNSDDFALDTLSPGW
RELVLHVSGELETKVERLPAGSFQPDFSSSGY
>A0A0J8YQB4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacteria symbiont BFo2 of Frankliniella occidentalis|TrEMBL
MNSLVPEIADNRSIRLLQLTDMHLFKTAQESLLGVNTWQSYQAVIDAVIAEQRPIDLVIA
TGDLAQDHSPEAYHAFAKGIRRLQKPCVWLPGNHDFQPAMVKTLASEGICDQKSVLLGDQ
WQLLLLDSQVHGVPHGLLSDYQLQWLREALARHPQRHTVILLHHHPIPSGCTWLDTHSLR
NSHELAEVLQDYPLANTVVCGHIHQEMDDLWQGRRVLSTPSTCVQFRPQCTGFTIDNQSP
GWRWLELRPNGEIVTEVQRLIDAQFQPDFHSEGY
>A0A452TUM6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ursus maritimus|TrEMBL
SFSFFHSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKS
MSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINK
ATITGKEDLVAFSSYV
>A0A658P4J9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. AAK_AS5|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPDRNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRARYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A806JGV4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Glaesserella parasuis ZJ0906|TrEMBL
MDDSYIFPLSSPIIRILQITDSHLFASDTCELLGVNTTQSFQAVLNMIMKESFEYDLILA
TGDLVQDHNREAYHRFAKMVKPLVKPLFWVAGNHDLQPQMRNALSIYSQIKPEKHILVGD
HWQIILLDSHIQDSPKGRLESSELAFLKRKLEVHPERYSLIVLHHNILPTNSAWLDQHSL
SNVNDLLATLKAFPKVKAIVHGHIHQEVDAQWNGYRILSTPSTCIQFKPHCNDFTLDAIP
QGWRELCLNIDGSIDTVVKRLDNNNFLPNFKALGY
>A0A7R8CSU3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lepeophtheirus salmonis|TrEMBL
MKQEVHSRSLLETFLVEDSFPGVLLRSCAVLEYITHCATHFWNDVGAREMGNLVPCGGTP
SNGRNGSSRRCSGSGRLLSANISGFSNRSSGDAKAGESLIPPASSIQGNSSSALGTIWRQ
SECINYRNFRLRRPKIRAIVALPKHSPQYNAAKWALERLGVESVLTFSTETAIQALNNGL
SSTPHLVLLDSRHPRNIDAEALAKHVRQSPYGNNIVVVGVVKKSFIEHEEVIVASHLRAG
FDRVLIDSGSRGYWMNELVLLLHNDVDTNIKLNCSESVLTALESCQDIVQITDKQNRLIY
GNPTAQKVLGFSQEELNNKCIWDYQSTKQNSNPISCDSSSSSSNNLLPTKSTLEPPLSDD
ADDVIKQKLDTGKVWEGPLNCRRKSGDYLALDTKIIPISFSSRRNSDHVIYVRKTPNLSV
PPIPSSSSAIVNNYNTMNNTKSSSCSNNTNNNHSNSSSCQISQHHLKHLSSTAHSSKALK
QQLHENHCTEVVSTSMASGNYYSGRRQSGSILPGMSIEAPITKIINIILSVQEKSPASIV
SELDKVIEILQATTGTTDLFSPELSKDGIKKRPDPVATDLLLELFYLIQQEMLLHKEEDQ
QILWQFPIQKIPLFIEQVFLISIIPLWQLAISLKIAQKSTLQNWLTLIEANYNADISYHN
STHAADVLHAVAYFLESPRVKDAFLCNSGNGLANLYNDITVLENHHASLGFKLTQSDKRV
NIFQNLDKDSYKLIRQGVIDLVLATDMSKHFVHVNKFASVFNTIESGECSVSDVVATDGS
DAVLSGVPNTPENVAILKRMLIKCADVANPARPLHICKVWAFRIAEEYFSQTDDEKRLGL
TVVMPQFDRATCSITKSQIGFYDFFINDMFDCLNNFDDFHKLVDIIQFNYNYWKQEAEEE
ENAKDLQSEEEVKSSNRSKSASEKEDIREEDEDIPT
>A0A3L7DX65|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Seongchinamella sediminis|TrEMBL
MPESRHMTCRIVDTGDPLRLLQLTDTHLCAEAGGTLLDMDTDRSLQLVIDRALRERGTPD
VLLCTGDLSDGGFRSAYQRLEGYLQKIAAPSFWLPGNHDDRAEMLAAVSDKVCLPGEIRA
GQWQLIMLDSQIPGEVGGRLGETELQRLAAALEAGRQDGLHALVCLHHQPVAVGSAWIDQ
QMVADAAQFWQLLDSYASVKGVLWGHVHQQIDRQRGSVALMASPSTCVQFAPGSTNFKAD
DKPPGYRWLELYANGRIETGVSRVTDAEFTVDLECGGYL
>A0A2K6DDF3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Macaca nemestrina|TrEMBL
CFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQALRPRPSQ
PPPPPVPHLQPMSQITGVKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIF
CVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAAD
VLQSTHVLLATPALDVSDLARSGLMQFLHPGFKRLPVQPPNSELALMYNDESVLENHHLA
VGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSS
GVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEIS
PMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQSPS
PPPEEESRGPGHPPPPDKFQFELTLEEEEEEEISMAPIPCTAQEALTAQGLSGAEEALDT
TVAREASPAQESLDVMAQDESLEAELEEVYLTQQAQSTGSAPVAQDEFSSQEESVVAVSQ
SSLSSLALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACTGTSGE
DTSALPAPGGGGSGGDPT
>A0A3S9WLA3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microbacterium oxydans|TrEMBL
MSAGTGSPYVFGRHEPASHVLVHVSDPHFLAGGIRLGGRYDVEANFARTLEAIRAVHPHP
AAIVVTGDLADLGEPDAYRRLRAAVEPVADQLDTPVVWVAGNHDERPALRAELLGLEPTE
DPVTGIWDLDGLRVIALDTSVPGWHHGDLDEGQLSWLADVLAEPAPLGTMLAMHHPPLPS
HLPLFDILELRHQDELADVIRGSDVRGILAGHLHYSSHGTFAGVPVSVASATCYTMNVAR
PAAEVNGMDAAQAFQLVHVYADTITHTVVPVTGAETGDYFSADWLERMAELSPEGRLEAF
SRKPGR
>A0A6M2A1S9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chlamydiae bacterium|TrEMBL
MRIAHISDLHFGSICWSPLQFLSKRWTGNLNFVFKRKKNFHYNRLIDLIDLFKQQNVTHV
SITGDLSVTSRRKEFKMARRYIDLLKNEGFAVFTIPGNHDQYTKRSYRKRSFYRFFDAKY
DKGCSFDLKQDKVTYTPLQDGFWLMGIDTAVATSLISSEGYFSPQLEENFTKALEEIPKH
EKVILMNHFPFFCNDSTKKQLLRGTLLKNILQKHPNVLLYLHGHTHRQTVADLRGSDLPI
ISDSGCTPHSKNGACHLFDFDDNKLKLDVYRYDGEWSKSESHSFKTT
>A0A6M1ZVZ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chlamydiae bacterium|TrEMBL
MSIWAIGDLHLSFGVAGKNMDVFGPEWASHADKIRTHWIEKIAEDDLVLVPGDISWGSTT
EEAAPDLEWLGALPGTKVMIKGNHDYWWHSISKVQKILPPSCHVIQNNAFDWNGFSIGGA
RFWDSDEYSFNEQIAFFEREIVSAKPHHEEAEVNQKIFARELLRLESSLKALNPKAKKRI
AMTHYPPIGPDLKPSKAADLLEKYGVEICVYGHLHSLKPDVKLSGEARGVSYHLTACDYL
DFSPLKIF
>A0A3Q3WLP7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mola mola|TrEMBL
MLNRELSHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTLREREKPMCHISGVKKLTHS
SSLSNSAMPRFGVKTEHEDALARELNDLNKWGLNIFHVAEFSNNRPLSCIMFAIFQAVFT
DLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLHEDNC
DIFQNLSKRQRQSLRKLVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDHYTDR
IQVLRNMVHCADLSNPTKPLAVYRQWTERIMEEFFRQGDKERERGMEISPMCDKHTASVE
KSQVGFIDYIVHPLWETWGDLVHPDAQDILDTLEDNRDWYQSTIPQSPSPPPVGQDKDLN
ACMDKFQFELTLEDSSEREQGDVGDEPTLPCCRLTPSVNNSPGFN
>A0A4Q1BDS7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arsenophonus endosymbiont of Bemisia tabaci Asia II 3|TrEMBL
MDSLFKLTTKQKSLVRILQITDTHLFANVDDTLLGVNTFGSFHAVIDAILARNENVDLVV
ATGDLVQDQSALAYKHFAEGIKRLSAPCVWLPGNHDYQPAMVATLAKAVILPSKQVLIND
NWQILMLDSQIQSAVHGKLSKQQLLWMKRCFDAYRERSHLLMLHHHPLPSGCTWLDQHSL
RNSHILADYLNQSQKVKAILCGHIHQEIDEYWQGIRMMATPLTCIQFKSHCTNFTLDTMA
PGWRYLDLSINDNGENVLDTQVFRLDSDKFRPDFDSGDY
>A0A5E4XV11|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea iniqua|TrEMBL
MLLCQITDLHVSRPGALACERVDTARALRHAIATINRWSPRPDAVIATGDLVDTPHPSEY
EVLRECLAELEIPLYLVVGNHDHRAALRATFPEHAYLHGGRQREHQRDTQDTGQAGDDFV
QYRVDLGPVTVLALDTQSPPNAGGHLCEARLAWLDAQLQACAGRPTIIAMHHPPFDTGIE
FMDGLGLSAQGREGFAAVVSRYRHIERVICGHLHRSIHAGVPGAPGVMASTCVSTAHQIS
LGLAPGAPGSITLEPPGFAMHLWQPGAGVRTHLAYVGPFDGPFTFDGALVS
>K8ACF5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cronobacter condimenti 1330|TrEMBL
MESLLNLPVAGGASVRILQITDTHLFAGKNETLLGVNTWESFQAVLASLHAEQRECDLIV
ATGDLAQDHTPEAYEHFAAGIASLPAPCVWLPGNHDFQPAMFSSLQDAGISPAKRVFAGD
NWQVLLLDSQVFGVPHGELSDYQLEWLERMLQQAPERHTLLLLHHHPLPSGCGWLDQHSL
RNAPALDEVLSRYPQVKHLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCAGFTLDTVA
PGWRWLNLHPDGLLTTEVCRLEGAQFRPDTASEGY
>A0A1B1NRF9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio scophthalmi|TrEMBL
MKVTSSSSAKDTIKLVQITDTHLFAAEDGSLLSVNTNDSFSAVVEAVTQQGFDFDAILAT
GDISQDHSDVSYLRFAQGIEPLKQPCFWLPGNHDYKPSMGSVLPSTQIVQAEHALLGEHW
QMILLDSQVEGVPHGRLSQQQLDLLDEQLRLHPERHSLVLLHHHPVLVGSAWLDQHTLKD
AEQFWQVVEKHDNVRAILCGHVHQDMQKVRSGATVISTPSTCVQFKPNSDDFALDTCSPG
WRELTLYADGQFETHVQRLAGGLFLPNFDSSGY
>A0A221K366|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sulfitobacter pseudonitzschiae|TrEMBL
MKILAFSDLHHARARAADLVTASADADLVVGAGDYCNMRQDIEGAMALLDGITAPLVLVP
GNAESVDELRAAAPRATVLHGEGLTIGGLRLFGLGCGVPPTPFGEWSCDLDEDTAAAMLQ
GCDGTDLLICHAPPKGMVDVTSGGISVGSTAIRAAVERAQPKLMMCGHIHDCWGQEGQIG
DTRVVNLGPTVNWFTLGV
>A0A5E4JEC6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MRFVEGEAALLLKDYAIISDLHIGFEEDLEDRGYIIPDQTPKFLQRIEKLREKAKKLVIL
GDVKHKIFLKRRKILYDFLAKISALFESVIIVKGNHDGKIEEYTCHFANIEVVNEFRIGH
SLLMHGNKNPSIENIKDVDTLMLGHFHSSYRIKTKIGIIEKRKVWTIYDFDNEKYFKDKK
VKTNIRTIFSFPCFNNFFEGGGEKLGPLAKYLAEHEVFTLDLVKIV
>A0A5E4JR17|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MGMKFKIQYTSFYMKSKIIQISDLHLGFDSKKSEKVEAVDPGLKKRAIELISEEKPDAIL
VTGDLVNVPFEENFSLATNFLNSLHKFPLMCIPGNIDYYSLISRPQKPILKESLEDKVEE
KLIVSEVELLKDPFRVDRSDMFRYLNIGLVKIKDRYHNFFEFNKDYKIYKKLDYYLKHFS
SEPVMNGRGINFIGFDSFIDMGIVLEGIAKTNMPDKSIYLAKSIDGELSTEHLKDRLKKI
KPGINIAVIHHPIFPIPHQNMLYGVFENGDYVARELLESGISLSFSGHKHVQGYTSRKIK
LSNGEEKDFHVCTAGSLFSSDIKKPYKDNSFNIITIEDQNVSVDYRELRSGSISRLCSVV
L
>A0A1A7Y8D0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Iconisemion striatum|TrEMBL
DWCLDQLETIQTHRSVSEMASNKFKRMLNRELSHLSEMSRSGNQVSEYISTTFLDKQNEV
EIPSPTLREREKPMCHISGVKKLTHSSSLSNSTLPRFGVKTEHEEALARELDDLNKWGLN
IFHVAEFSNNRPLSCIMFAIFQERDLLKTFRIPVDTFVTYVMTLEDHYHANVAYHNSLHA
ADVTQSTHVLLSSPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFL
>S3J1L6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cedecea davisae DSM 4568|TrEMBL
MADGGRIRILQITDTHLFAGKDETLLGINTWKSYQAVIAAILAEQHACDLVVATGDLAQD
HSAEAYQHFAEGISRFSAPCVWLPGNHDFQPAMFSALLEAGISPAKRVHIGEHWQILLLD
SQVFGVPHGELSDYQLEWLERQLAAAPERHTLLLLHHHPLPAGCSWLDQHSLRNAAALDA
ALKAWPQVKTLLCGHIHQELDLDWNGRRMLATPSTCVQFKPHCANFTLDTIEPGWRWLDL
YPDGSLTTEVCRLQGCKFNPDTASEGY
>A0A508TDX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bradyrhizobium ivorense|TrEMBL
MTEFRLTQISDTHLARRLKILTDNFHRVAEHIDATRPDLVLNTGDVSWDGPTSRADLVFA
KEQHDALPVDRRYLPGNHDIGDNPTAVGPAPSQLPTTETCNVFTSVIGEDRWQFDAAGWC
FIGLNSLIMNTGLDREAEQFDWLGEQLGKVGGKPVALFLHKPLYLDLPADPERVETAIRF
VPQPARRRLIEMFGKVDLRLVGSGHVHQRRDYTFAHVRQIWAPSAGFIISDARQERIGIK
ETGLVEYRFRPDSFEVRHVKAKGQADIDLDTLIAQLQS
>A0A508ST95|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bradyrhizobium ivorense|TrEMBL
MSGHDHDHHNEDNGVSRRKVLECMTWASTGVLWTISGGVPRSLGIVGSAAAAEPAGMTFL
QISDSHVGFDKPANPNAIGTLEEAINQVRGIPAKPSFMIHTGDITHLSKAKEFDDADRII
SQAKLDVHYVPGEHDIIDEEVKLYKERYGKGTKGAGWYSFDAGGVHFIGLVNVVDLKGGG
LGNLGNDQLEWLENDLKGRSKSTPIVLFAHIPLWTVYPQWGWGTEDGGRALEYVKGFGSV
TVLNGHIHQVMQKVEGNVTFHTARSTAFPQPAPGSAPSPGPMKVEDAKLRSMLGVASINF
KQGTERLAIIDTPLQG
>A0A669Q554|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Phasianus colchicus|TrEMBL
QNREFGGRASLGGDGGAGPPLVSPCPAVMPCCPAAEDAQQKLSLETLDELDWCLEQLETL
QTRHSVGEMASNKFKRMLSRELSHLSESGRSGNQVSEYISSTFLDKQHEVEIPPALPKEK
ERERRKRPMSQISGVRRPAHGPRPAAIPRFGVRTEQEGLLAKELQDTNKWGLDIFKVAEY
SGNRPLTVLMYSIFQERDLMKTFRIPADTFLTYMLTLEDHYRSDVAYHNNIHAADVAQST
HVLSSSTPVSRGERGGEAACVGSPRRDQHHPADSELALMYNDASVLENHHLAVGFKLLQE
ENCDIFQNLSKKQRQSLRKMAIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNY
SDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMAEFFHQGDREREKGMEISPMCDKHTA
SVEKSQVGFIDFIAHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPRSPSPPPEVGSE
VPPADPGKSQFEMTLEEEEGESDTEAEGPESPLEEDNSGSKTSATDDSESADTERLSPGS
GDREVDNRRVLEGTLPKDRAGGGCTAPDPEGGRELCLDTEGNVTFLPLGT
>A0A1Y6IUB3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio mangrovi|TrEMBL
MDVSFHTEHLDSVKLLQITDTHLFASDEGSLLSVNTADSFNAVVDEIISRQVEYHLILAT
GDISQDHSDVSYQRFVDGIQPLQKPCLWLPGNHDDQPVMKTVLACPQITQPNHVIVGAHW
QMILLDSQVFGVPYGHVSPEQLQQMDDILCQTQDRHTLILLHHHPLLVGSRWLDQHTLKN
SEQFWDVLLKYPHVKGVICGHVHQVMERDYHGVRVMSTPSTCVQFKPQSDDFALDSVSPG
WRELELHPDGQLTTQVGRLKSGLFLPDFSAHGY
>A0A6N4XKT7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chryseobacterium fistulae|TrEMBL
MNLSLKTSFKKKSVPFRIILSAVLLYSCATYNVKKGKNLYEVNNIKSENKFKIFLVGDAG
NADEIQAQHTLKFLKNKLDSADSNSMLIFLGDNIYPLGMPKDTDEEYPLAKKKLENQLII
TQNFKGKTLIIPGNHDWYHGLEGLKAQEDFVKNYFNDKKAFLPKGSCPIDDINLTKDIKL
IVIDSEWALINWDQFPGINKNCTIKTREDFFTEFKDLINKNQDKKIIVALHHPVISTGTH
AGYNSLKSHLYPLKSKFPAPGFASVLNILRSASGASIEDINNQHYADLAKRLKSIVQDKE
NIIFVSGHDHNLQYHEDRNIKQIISGAGSKTDPSTIAEHTDFSYGGSGFAILNMRKDEST
DVEFFSTKNNQFKKFSHIQVIEKPKEFINPYPNSFPKTFSSTIYPKKLTEKGKFYKWLWG
EHYRYYYGIPIEAPTANLSELDGGYIPFREGGGNQSNSLRLKAQDGQEFVMRGVKKSAVR
FLNNMAFKKSTFGDELKNTFPEKFLLDFYTTNHPFTSFSVGNLADKIHIFHSNPRLFYIP
KQSALGEYNDNYGDEMYMIEERFSSDSKTLKSLDNAQDILSTDDILKNFTKNYKYSVDKE
SYIRARIFDMFIGDWDRHSDQWKWAEYHQGDKVIYKPIARDRDQAFSKYDGAAFKIIMNI
PAIRHMKTFKDDIKNVKWVNMEPYPLDLVFLKSSEEKEWIEQAKFIQEHISDQDIEDAFT
NLPKEVQDETLADIKRKLKSRRLKLQDYATRYYDVLQEKVPLAGTVNPDQFTITKTGNSV
NVKQYKLDKNKENPELVFEKTYYDTKTKELWIYGLEDDDLYEVLGDGKPKMNIRLIGGYN
HDVYNVKNGSKVKIYDFKSQKNTYNAPSATKNISDDYNINTYNYKHPKYNYFAGYPNVDY
NPDDGLILGFLANYTVNNFIRDPYSHKHSLKGNFYTATAGFNLIYKGIFKKAIWGLDFNI
DASYTTPRFSENFFGLSNESPYNKENTERRYNRARISKFSFAPSISKKSWMNLQHQFQLS
FERNKVQRKDNRFVDISPDVRPEVFTNQQFAGANYTFSYKNLDNVAFPTLGMEFMANADW
KTNLSNFNKNFLTLSGTLTIDHRLDKRGNFVLANSSNAMWISNTNFEFYQAASIGGNNGM
RAFRNERFSGRSYFTNNSEIRWDFGRVRNNIVPANMGVLLGYDVGRVWNNNENSRKWHQS
VGVGFWMSIVEMVSARLNYFQGTDGGRISAGVGMTF
>A0A454CY66|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio harveyi|TrEMBL
MQPSSDSIKLLQITDTHLFEADEGSLLSVRTADSFAAVVKEILHRRVPFEYILATGDISQ
DHSAESYQRFAEGISPLKKDCFWLPGNHDYKPNMGSVLPSPQIQAVEHLKLGDHWQVILL
DSQVVGVPHGRLSDQQLTLLEEKLAENPQRHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFDNVKGILCGHVHQDMNIIHKGIRVMATPSTCVQFKPNSDDFALDTQSPGWRELE
LHSNGDISTQVNRLPDGQFQPDFTSSGY
>A0A443WIK4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella michiganensis|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFTAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQVLLMDSQVFGVPHGELSDFQLEWLEQKLTEVPQRYTLLLLHHHPRPSGCSWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A3R9CAL0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. FDAARGOS_558|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIQQILKQHPEADAIIHT
GDLAQAPTPITYKRYINFMQTLGLPFFQTLGNHDNVDHFPLHNENHQQPVVVGLGNWRVI
MLNSAVKGKVDGHLSSEQLENLANLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFQNVKALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLNNDGSFETKVFRLENFKTRINTDISGY
>A0A379FBF8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteus vulgaris|TrEMBL
MESQFELSVKHKNTVRILQITDTHLFANVEDTLLGINTYRSYHAVLNAIREQGLEVDLIV
ATGDLVQDQTFDAYQHFADGIATLTPPCVWLPGNHDYQPAMIDALNQAGILSAKQVLIGD
SWQMLLLDSQIQGVPHGELSDCQLDWLTRCLESQKHRDTIILLHHHPMPSGCTWLDQHSL
RNSQELAERLKGHTQVKMMLCGHIHQEMDEMWNGIRMLATPSTCIQFRPHCTNFTLDTVS
PGWRYLEMSLSSDEKGKVETQVYRLAGTEFCPDLDADGY
>A0A5C8BMX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp|TrEMBL
MTFQVSTLSQKDFVMIQISDTHLLETPEVEFLGMHPEQSFHAVVDLVRQQHHEIDVIVHT
GDLAQNPTTVTYQRYLHYMQSLGVPFFQTPGNHDNPALFPFHEADPSQPTVVQLGQWCII
LLNSAQAERIDGKIAAAQLQQLTELLTQYHDRHIIIACHHHPFAMQSAWIDQHKLKNSSD
LLDVIQPFSNIKAIICGHVHQDSIHTWQGIEFLSTPSTCIQFKPKSAAFALDEQHPGYRY
ICLKANGEIETQVYRLEVSHRNSSTEVLGYD
>A0A5M7LLS9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. VH_25|TrEMBL
MDSLLTLPAANSSEIRILQITDTHLFAGKHESLLGVNTWSSYDAVLDAIIAQQRDYDLII
ATGDLAQDHSVEAYQHFAEGISRLPRPCVWLPGNHDFQPAMVDTLAAAHINAHKQVLMGE
QWQIVLLDSQVYGVPHGMLSDYQLEWLDNALARFPQRHTLILLHHHPLASGCTWLDQHSL
RNSHQLDAVLQRYPLARTLVCGHIHQELDLEWHGRRVLATPSTCVQFKPHCTSFTIDTVA
PGWRWFTLHPDGGLETEVNRLDTDAFRPDLDSEGY
>A0A5K1ILM3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Collinsella aerofaciens|TrEMBL
MKILAIADTEERCLWECFRKERFEGVDLILSAGDLDPDYLEFLVTVINKPLIYVRGNHDD
RYARHAPGGCICVEDSVYTYRGIRIAGLGGSMRYRDGANMYTEREMSKRMRKLSRKVRMV
GGCDILLTHAPAAGMGDLDDLPHRGFECFNTALESWNPDYMVHGHVHQSYGCDFQRERQH
ACGTTIINACGYTQFELDQTRYPIRGWQAAWLNSQTMRRELKRHDAIESSTARTPW
>A0A1Q9PE79|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Heimdallarchaeota archaeon AB_125|TrEMBL
MLPKAEHMKNRKSLQVFTLILIFMMPATVQFFQVSAKVTEIIPYQIHLSWQHDTSTTMTM
SWKTSEVTESIVQYGLGSTYGSEETGLSGTLHTVELTGLTPNTVYHYRVGDGNTWSIDLD
FKTGNVDEHAKFLAIGDSRTNRADRRVSSRQISKVSADFAIFDGDLVESGLDANQWNDWF
YDLKDLLYEFPFMSALGNHEKNHTNYYKNFAFPGKEEYYSFNYGPVHISVLHTCVESYGG
TFDEQIAWLHTDLQAHNDYPWKLILMHKPAYASSTRYNLGQYDDIITLLVPIFEQYNITM
VVSGHDHFYERLMNNNITYVIAGSIGAPLYDLSPALTIPQSIISEAVYHFTLLDVYPNQL
NFRAFRMDYSLIDEFTINKDDKPDLRVEVVQNKYTGYFNLTQEVNIRVTNIGTQDITEVT
EASITNDTTVLHTQAIPALDVGESYVFQKIWSVSEPGTYNWTITVDDGEIIDEVVEGNNE
IALFFYALEYPTTETSYSFNILMIVSFVMMLMIATVIRRKRKE
>B7ND23|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A1E1XFA4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Amblyomma aureolatum|TrEMBL
AAEKMHYECTLSATSEAAIDNYLNGQPHLVFVDSRSKSAIDPVALCRTLRGFRGSQFTCI
VAVVKKGLADKEEAAIIPLLKCGYNRWFTETCSLGVCLNEMIQIEHNDLISLWKLRASEA
LFSALHYTRDGVIVTGASHEIQYMNRAAEKLVGYSVEEMLGVDAQELHRTDSLKTDVASN
INMQLKKGKEWEGTLFHKRKSGECIPMWSKIAPVEIHTGKSDHVVYIKECPFFMEKPFSP
DAVGMNRRQSFAKFHAMTLEAPITKVINMLVSTQENSSAMVAQALDRVIDILRSTELYNP
QLGVGQGKSEDQMTSDLVTGLINTGQKPTGVRRLSHETSLMKVNVVNTTAPSGALPSLNT
APPKIKELLENDVKWEFDIIELETLTGRRPLIWLGLSLFSKLNVHTSLECDDATIRNWLQ
LVESHYLDNPYHNSTHAGDVMQATAYFLLKLRKKDIFDPLDEAICLISAVVHDIDHPGKS
SPFLCNSDHELAILYNDRSVLESHHAAFAFKLTLSDEKVNIFQKLDRDVYRSVRLSIIDM
VLATEMTKHFEHLSKFLNAFQKPMQEEEGFESEPLQEHGESGSLRSAENIILIKRMLIKC
SDVSNPARPIQLCIQWAHRIAEEYCAQTDEEKRRGLTVVMPAFDRATCSIPNSQTGFINY
FVRDMFRAWSDFGEFPELMEYIEKNYIYWKDKEPSSGQQGNR
>A0A7Y3CX61|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonadales bacterium|TrEMBL
MRVLQITDCHLGERAGEQLAGMDTDASLDYVLELLRREQYKDGRLAADLLLATGDLSNHG
TAAAYKRLTEKLRGFNVPTAWLPGNHDTRDLMIDTVGIDRLPRLVRLGNWAICMLDSAVP
GQVGGELGPTELNELALELRSLPADCHIMVCLHHQPVPVGSAWLDQQQVADADKFFALLK
GEQRLRAILWGHVHQEFNGTDARVPGAQLIASPSTCIQFAPHSDDFKLDTLMPGYRWLDL
HADGRITTGVSRVRDAELSMDLASSGY
>A0A2K5HC00|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Colobus angolensis palliatus|TrEMBL
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQ
KDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIF
NVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAAD
VAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDES
VLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMV
ETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKE
RERGMEISPMCDKHTASVEKSQVSNMRFSKYLISVSCSFCLSK
>A0A8B8FHK3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sipha flava|TrEMBL
MGYASNSKDVFKYRHESIEKYNIVTLDHRVYSKSADTDEWNVRRPVKNSGTAGNRILIIL
TAMWDNCCRRSGSTSDLSRETVDAYSPINRSDSPLAPQTPENFNYYMFGCSKYIQDLRSN
PMLKKILIVTSKDDSVWQSVTTTARNLDWAVNRVSSSEEALECFHKGNEVPAVAFVDCRH
QNDKTVDAHQIARSLRSIRKNAHVVLVALVRKSFVVRNEKDVTSILTSGFNKIIVETCNK
NVWIKELQQLEKEDISVRSMLIQQDAVLAALDKTKDLVIITDLKHNIQYMNKMGSIVLGY
APEDVVNQPLAVFHQLGDIDQITKKLQKNIEWDGKVSWKCKNGEPVYLQCRAFPFRSFGK
ETTNFIYVQETIAEGHGYPRGSVPSIRKGSYDLKSINSDGAQSARRQSLAKLHNLPLEAP
ITKVISLICTAQENSNDQVVQILDKVVDILRVTELYSSHLKTENIKFDDPVTSDLIGALI
TQGPMHVTSTRRSSNDSATVKNQPYGMGIAKMNFMTSVTPQIKELLDMSLYWDFNVFKLE
ELSMKRPLVHLGMNLLMHFEVHKTLGCDERTLHAWLTVIESHYHAKNTYHNSTHAADVLQ
ATAMFLEKDRIKRLLDQLDEACCLIAAITHDIDHPGKSSAFLCNSQNDLAILYNDISVLE
SHHAALTFKLTTRDERLNIFKGLEKDTYKVVRQNIIDMILATEMTKHFEHLAKFVSVCNK
PSSLDEAPVDGLTPSDVSPETIAPTSAEEVNLVKRMLIKCADVSNPTRPLKMCVEWAKRI
AEEYFNQTDEEKINHLPVVMPMFDRVTCSIPKSQIGFMDYIINDMFETWDSFIDMPEMLY
YMRSNYQYWKDLEEKGTISINEICKTMTTTLPKIPESSGNH
>K1J665|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas dhakensis|TrEMBL
MRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHPFDLILATGDLSQDHSPESY
QRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQVILLDTQVRGKP
HGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNADDLFAVLARHPQ
QKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGWRYLTLYPDGRIA
SQVWRLPVGQFVPDPDATGY
>A0A2H5X7X3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR16|TrEMBL
MMQRLSWTAFFALMTLAGCFAQQKLISQVHLSWSEDPQTTMSITWQSSKPLSSPVVQYGE
GNTLSQTAMARRIRYEQETGPLYQVTLRNLKPDTLYSYRVGDAGKGWSEVRTFRTAPSKP
PARFVFTAFADHGVTPAAEQNVRRVLSGEKPAFHIIMGDLSYANGNQPVWDSWFEEIEPL
ASQVPFMACPGNHEDERGIRFATYLARFALPGKELYYRFDYGGVRFIMFNSQDFRDAEQL
RWFEQELREAHRDSEVRWVIVSMHHPLYSSTVRRLNDTARIEVLQPLFDKYRPDLVLLGH
HHNYERTYPLLSMKPRSHHPNRYSRGQGVIYVTSGGGGKSLYDLTPEQPAFTAKRERCYQ
YLRITVSDRSLVVECYRTEDNSLLDRFEIVR
>A0A248K5G3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella bongori serovar 66:z41:- str. SA19983605|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLTDAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELHANGLLETEVHRLQDTRFRPDTASEGY
>A0A087L7E3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia sp. Ag1|TrEMBL
MESLLKLPVASGEAVRILQITDTHLFAGESETLLGINTYSSYHAVLDAIIAQQRACDLIV
ATGDLAQDHSQAAYRHFAEGIVRLPAPCAWLPGNHDFQPAMVDALAAARIAPSKHILLGD
NWQVLLLDSQVFGVPYGELSDYQLEWLERGLMAHPDRYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLAAVLARYPKVNTLLCGHIHQELDLDWQGRRLLASPSTCVQFKPHCTNFTIDEVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A327MZQ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEADRTLLGMNTRDSLQKVIDLVRAQQPRIDLILAT
GDLSQDGTLESYRQFRDMTHQLDAPARWIPGNHDEPQIMAEAAVQSALLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDQFRNGVRLIASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGRLETGVERVTGFDFTVDYGSNGY
>A0A5E6YZV5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MIRPTLLALALFSVINSACAAPDTPLPHSPGAPYAASGLADRIVLTPGADPAREMAVTFR
TDTRQQTSQLQLAPALDGPQLAKAAHEVQGTSISLDNENGAALFHQVRLHDLQPGTAYVY
RVKGSDGWSEWLQFHTATKSFKPFNFIYMGDVQNDILSLASRSIRQALQSVANPALIVHA
GDLVSQREDLVHDDQWGEWNQAGGFNYGMIPQLVAAGNHEYLDGLNPDGSETRTLGPHWS
RQFALPQNGVDGLKDTTYFVDYQGVRFIVLDGTSALDMGTLDQQTRWLEQSLKTSPARWN
IVVTHQPVYTCARPEDTEPLKTAWKPLFERYAVDLVLQGHDHCYSRVSNEAGRVASKAAQ
AGGKIQGPVYMVSVAGSKMYGLNDRARQQPDRSAEETQLYQTVDVQDSRLKVRSYTAAGK
LYDAFDLERDGKNRNHLREPVNNLPAERACTQTAGPDGFACSSRAK
>A0A5E6ZYX4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MANNKVAGLSVGVCFLFAVFMAHAVAEAPRHIVFASDTQYPWTDKTDSREPESSEEFTTR
SKWLVESQLASIADFRNHHGSQATVPLMINGDITAFGHGWQRDYMASALNKHFGTDYLYG
LGNHDYENNVDDCFSNSCAAGSIVEFKEHHQGKVDSFDLTITGSAVNKLYSGSLAYSKTI
GDVHLVQLNNEPTYSTKISSVWNPTTFDITSALDWLETDLRLARVAGYAIIINMHKPHEM
MGDASQRKRFIEMIDKYQVTAIFAGHLHREGGYGFWKGSASMFLSGAPSQQTYLIASFSE
DRKQLQVYLVKNNRWQDRTLIETIPVKSIWASRP
>A0A5E7AGX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MKLQIYSDLHNDFCTFDAPSTGADIVILAGDINSKAKGVIWAGETFSCPVIYVPGNHEYY
GGHLDHTLRQMRNVASAHVRVMDNQTWVWNRTRFLCATAWTDFSATGDVVAATHTAAEWM
NDFRVIRIDHNFRRLRPSDLVKRNHATRDWLVQELAKPFEGHTVVVTHHSPIPEVSGDKH
DGHLSAAYSNRWHSLVEKADLWVFGHTHRTVDVSLGGCRVVSNPRGYPNEKTGFDPG
>A0A6M5D596|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kosakonia sp. MUSA4|TrEMBL
MESLLNLSLAGESRVRVLQITDSHLFAEKHETLLGVNTWESYQAVLDAIQAQQRPCDLIV
ATGDLAQDHSAAAYQHFAEGIARFTAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGD
HWQILLLDSQVFGVPHGELSEFQLEWLENKLSDSPERHTLLLLHHHPLPSGCSWLDQHSL
RNAGELNNVLQRFPKVRHLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLYDDGTLHTEVCRLESTQFRPDTASEGY
>A0A7U4E2S0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella baltica OS117|TrEMBL
MLKEAVSYSIAEGESVRIVQVTDPHLFADPEAQLLGVNTGKSFDAVLNTIRAVDYPAHLM
LATGDLSQDYSAESYQQFVKAVTPVGLPCHYLPGNHDDPRIMYLHMQGEQIFGQQRILAG
NWQILMLDSTVRGKPGGNMAETQFELIDEAIAAHPECHTLLVMHHNPIVVNCTWLDQHCM
DNGAEFIARVAKYPQVKGLLWGHVHQCIDTHHNGPHGSMQLMATPSTCIQFKPLSPYFAL
DSVQPGYRLLELKADGSINTKVYRVPGNHFSPDNNSSGY
>A0A7J7F6K6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Diceros bicornis minor|TrEMBL
MPCALTFCPRGVPLAEQRAERAWWKPSTEKVLRVCFDVENGPSPGRSPLDPQASSSSGLV
LHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSV
RNNFTILTNLHGTSNNFMQFDEYE
>A0A5M8NV99|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Ordinivivax streblomastigis|TrEMBL
MHTLFTTLFTGRTNRQLTSIKCLIVLFAVFIFACKDNEKEAAAFLEIAAEQQTIHFETPD
VDTVLVTVKTNRTFTASVATTGQSWCSTQIIKDKETDNLIVNVVKNTTTEERTTTITVTA
EGLPTGIELSVKQASGDAPPFIEIAEEQRTLQIEPDASVIFVTVNTNQSFVATVATAGQE
WCTAEITEGNEAGNLKISVSKNEMARERTTTITVTADELPAIEITVNQHIVVYEGFPRFA
VISDIHFENNRGEGAQVKVPKALKNLMSKTPLVDALFVVGDLTDNGREDQYDILKAAFAN
PSNISATVPVYYLMGNHDNLSGANAATYYRNKLGQPLHQYIIIKGYPFITISQTGTASTD
YNNEAQTFLRDHLAKAATDFPGRPIFVFTHVPPQNTCYGSSVSDGWGSSVFPPILRNYPQ
VIVFSGHSHFPLGDPRSIHQGDYTAVNDGSTTYSEVEPYVVTEGIHPAKYEYITEGVIVN
VKEEGNTVEMERWDTYRNEEILPRWQVKAPFDGSRFALEYKNRNGQPVPSFATGVKPTAS
GSEDEWTITFPQATDNEVVHHYIVDVVNNQDVAVRSIRRFSQYYLNSAMPPFLTTAFSDL
PEGEPLVAKVTAVDSYNNRSEPVVSEPFIPVVVSVDPPPAAGHWLFDDADLTKALVGEPL
VPSGSGFTSIDGPAAGNKAVRVPQGSYYKLLHGFAANGGGSSVNEYTLMIHLRVPSIDRW
YALFQTDLNNGNDGDCFINPSGKVGLGDSGYSSASLTANVWHRIVVTAKLGAWYRIYLDG
TLAVDSNTPAVDSRYSWSLQGVLLFADDNGEDNALDVAEIAVWNQALSSAKVKALGK
>A0A2H5XP34|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR19|TrEMBL
MKKRFIILSDLHLGEGRIVNGQINYKEDFVYDEDFYEFLRWWVKDSQSSGYDFTLVLNGD
IFDIIKSIHKKGKVYKKDVFQFLDTSINNHRIFFNALKDFESEGGKIIYIVGNHDHPVAS
PEIQTFILEKAGLKTKFIKREFFEDGLWIEHGNKYEVINRTDLVNIWLKDESGEEILNMP
WGTRFVVEVVASFAFEKPYLDRWRPLGKAMKWGLIFDTKITLLAIIRMIKFVIKNRKIYD
PIRRRYIFIPLSSITDAMGHKIVDRSAKILLKRPDIKAVVMGHTHKALLERYIDKVYANS
GTWVPFVSFDAPYIGIVDKRSFVIADIPESKNNIFIGAFIWHGRERMFEEIKEIRYSAQN
L
>A6D6B9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio shilonii AK1|TrEMBL
MLQLTDTHLFAPQDGCLLSVNTQESFNAVVAEIVAQGTQFDALLATGDISQDHTEASYEK
FVAGIEPLALPCYWLPGNHDYKPCMNSVVSSPLIQDVTHVLLGEKWQVVLLDSQVVGVPH
GRLSDSQLEFLDRMLSAHCDRHTLVLLHHHPLLVNSAWLDQHSLKDADEFWSVVEKYDNV
RAVLCGHIHQELDEMHGGVRVLATPSTCVQFKPNSNEFALDVRSPGWRELELREDGRLHT
EVKRLANGSFRPDFNAEGY
>A0A6H0IYK0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aquisalimonas sp. 2447|TrEMBL
MQLTDLPRGRPLRVLQITDTHLYGDGGQLAGVDTEAAWEAVVAALRGKEQRCDLLLHTGD
VIHDGALDTDAAYCEARRQLQGLGLPGLVVPGNHDDAGAMERVFHTGPVRLVGHLVAADW
LFITLDSTVPGATHGHLSATQLQWLDDCLGANDGRHVLVGLHHHPVPVGCRWIDRIGLDN
GRDLFDVLDRHDAVRAVVWGHVHQEFDGWHGDIRLLASPSTCVQFDPASPTFRIDPRPPG
YRWLELQPDGRVRTGVERLTELPAGLDVGIAGY
>A0A8D2IWU5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Varanus komodoensis|TrEMBL
ARGKSQKTKQNKTHPSSCSPPSHFFLFDVENGPSPGRSPLDPQAGSSSGLVLHTTFPGHS
QRRESFLYRSDSDYDLSPKTTSRNSSLPSEQHGDDLIVTPFAQVLASLRSIRNNFTLLTN
LQGTSNNLGICPAASISVKIKFNLCSLSPTDVNEQNTNGNNLL
>A0A395LE81|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ensifer sp. M14|TrEMBL
MHADTQPLLRFGVIADPQYAAVEPNLVLGRYYANSLTKLAEAIETFNAEDLAFVVTLGDI
IDRDWQSFDAILPLYERLRHVRHFLLGNHDFRVEPERLVEVFARVGMPGAYQTFAATGWR
FILIDGNEVSLFAPPPGDPRLAVAERWIETLKALGADNAQPWNAALGDRQFAWLEAELHK
AETAGERVVVMGHYPVYPPNAHNMWDSERIVDLFGRYENVAAYFCGHNHDGNYGLVDGTH
FVNIKGMVETPDTTAYAIVEIHTDRMEIRGYGRETDRTLALTTVTPRLAASANR
>A0A2S7VV48|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium angustum|TrEMBL
MQTYSLPQTNPDSVVLLQITDTHLFANESGALLGVATQQSFHAVLNAVDASSRKFDAIVA
TGDISQDHTPDSYQRFAEGISRWEQPCFWLPGNHDYQPTMASILPSEQIKDCEQILVGEH
WQVVLLDSQVAGVPHGELSHHQLALLDHALSLHPERHALVLLHHHPLPAGSAWLDQHQLH
NSDALWQVIDKHPQVKAILCGHIHQELDRIHRDVRVLATPSTCIQFLPDSDDFALDQVTP
GWRYLELTATGDIITHVERLEGDVFQPTFDSAGY
>A0A6P8JFD8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila mauritiana|TrEMBL
MGCSPSTLPPAPSAGQTGERGSLPLDASEKDESRLFCIKLRRSRLRRCSCGGVTLQPPSD
GNGSTAGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHSVVRRATGSTG
TSGTSSSGGNSRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLVFH
KSDSICEAITAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSSKNLDAEH
IARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQIL
HSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLE
DIFVSDLSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVP
GGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKEN
CSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSI
IRTGSSTRTAAIVPAKMKSNPIIMELLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRF
DVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDMLVMDR
MEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLGDDKI
NIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPRDHNPQTDEETSIL
MRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRATCSIPK
SQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLAEIMAKQPPVGK
MANSK
>A0A7H9JZF5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEKRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQEAGISPAKCVFTGD
QWQILLLDSQVFGVPHGELSDYQLDWLETKLAAEPNRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLAKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLHADGSLTTEVCRLAGAQFRPDTASEGY
>A0A8C5S9N4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Laticauda laticaudata|TrEMBL
MKEQNSCVGTGHPPMAGYGRMDPLELAVSPVKRLRTEYSFPFLFAEEAYQKLASETLEEL
DWCLDQLETLQTRHSVSEMASNKVGKPPPPPGSPPFTPPPPPPVHDNFSLHFWCAEFGTF
CTKSSRFC
>A0A1X0WB30|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rouxiella badensis|TrEMBL
MESLFKLPLVDGAKVRILQITDTHLFAGEDQTLLGVNTFRSYRAVLDAISAEQREVDIIA
ATGDLAQDQSVEAYHHFAEGINRFHAPCVWLPGNHDFQPAMVDALAEAGIHPSKQVLLGN
DWQILLLDTQVFGVPHGELSEYQLDWMTRCLDQYPDRFTLIMLHHHPLPSGCTWLDQHSL
RNAHTLATVLQAYPQVSTLLCGHIHQELDLDWYGKRLYATPSTCVQFKPHCTNFTLDTLA
PGWRYLTLHPDGRVETEVCRLQTSEFSPDADAEGY
>A0A2T0B2S8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clostridium liquoris|TrEMBL
MAIYAISDFHLAFTTDKPMDVFGANWYKHEEKIKENWLNTINKEDTVLIAGDVSWSMRME
EGMMDLEWIHNLPGRKILVKGNHDYWWTSITKLNNLYGDMKFIQNNHFSYDDYAICGTRG
WICPGGEKFTVQDEKIYNRELIRLRLSLETAVKEGFDKFIIMLHYPPVNDKCKESGFIEI
FKEYNIEKVVYGHLHGISKDKVFEGKVDGIEYILTSCDYLDFKPTRIL
>A0A6F9ZMT8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacteroidaceae bacterium|TrEMBL
MAQTVMTNLYIPAYYQQKQISMNAMKRKRNGVVALLMMLTLSLVPLQAQRYVLTAVAPEG
STYLTLSPSDSVILLTAASHQYAATVKTNLKVNATASQTWCGTSLENGTLNISVPANTEN
DVRETTVALTAKDGRNASIRLQQLGLHPQVIVAERAVSLINNDTRFTLTLAANTGFTQTL
PAWVKQTGKTADRQTGAVCYEYTAEAMAQPGLREDKIILSPEGGTPVTVSVSQSFEGYPR
FAVMCDLHFGNQKGEGPLVKVPQALRHLLSKGSIDALFVCGDLTDGGTQEQYADFKRVFA
NTDNIPAGVKVYCVQGDHDNYDADGHENFRTATGQPLDQFIDIKGYPFILVSIRGRRGYD
GYGNTEREFLKKSLARAAEDYPGKPIFVFTHVPAYGTVYGSCAGEGGWGSSQLTDILEQY
PQIVLFTGHSHFPLGDPRSISQNVFTSVNAGSSTYSEIEPDAVDEGIHPDQYDRITEGLI
VQADGNSNLEIQRWDTYSNEEILPRWHVTAPHDGTAFTYKDRTGGKAPWFAETDRLTVSD
ITEDGCTMTFPQATDDEAVHRYVVEITGKDGRAVSSRTCFSGYYLNSRQPKSFTMTFNGI
AEETELTARVRAIDSYNNESAPLVSETFRIAAYTPDPDTERPTADLLDVVWDSNGEATDI
SEQNSTITHGTELPVMADKASENGHVPHFSGNSQCYYRVDYAGNAAMKTAFQNAFSLETV
YTPDNLSNMCVLSGQENGFAGIEQASGGQICFYAYVGGGYKILKSNVTATAGETYHVVAT
YDAAAGVTRLFVNGKPAGEMAAKGTMAFPGNENAHWAPHSSLPKSGTPPLKIKVENGRSA
AYAGHLSKGLLGI
>A0A6N1CNZ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas bijieensis|TrEMBL
MPSVSSLTTADAALLVQLSDSHLFAEADASLLGMNTRDSLRAVIDLVLKQQPDIDLMLAT
GDLSQDGTLESYEAFRQLSGLIEAPARWIPGNHDEPQVMLEAAVKSTLLDPVVDIGNWRV
TMLDSAVPGSVPGFLAEEQLILLANALSEAPERHHLVCLHHHPVSVGCVWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEVDRVREGVRLLASPSTCIQFEPGSEDFAVGSQAPGYR
WLRLWPDGRLETGVERVVGFAFTPDYESNGY
>A0A846KQS6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Anoxychlamydiales bacterium|TrEMBL
MITIAHLSDLHFSNISIFPLTLKRFIGTTNLLITRKRSYIDMHLSKLPNLLKSLDVNNIF
ITGDLSSTSLKKEFEKAKKFIDSFDENIKFFIVPGNHDTYTKQADKCSYFQNIIKSKNII
DSKEKKIHLFDLSEKWVYIGLDTTLVTPLFSATGLFSNEMEKDLIDILEKIPKDKNIIIS
NHFPIFHKAAKRKRLKRREALLNVIKKYPNIKLYLHGHTHKRSITKEENMPYMICSGCSS
HKKNASFNLLKIEDDKCFMQSYILQDSNWKKDKVEELNFS
>A0A645A193|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MTLLLQLSDLHIREPGRLAYGRIDTTPYLAQAVASIGRLPQRPDAVVITGDLTDFGSASE
YEHLQSLLAPLGDMPLFLLPGNHDERQQLRASFPTHTYLGANGFVQYSVPIGGLQLIALD
TVTPGQSEGHLCQERLDWLAAELERQRHRPVVIAMHHPPFETLIGHMDRIGLLSGARELE
AIVARFTNVERVICGHLHRSIQVRFGGSIASTVPSAAHQVCLDLAPNAASAWTLEPPSFA
LHALPTGGRLVSHLAASGRFEGPFPFYDGGKPID
>A0A645FG86|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKYAVIADIHNNLQALSNILERTKKDGMDAVFVAGDLTVGGESEKLKAVREVLNKSGVKY
FVTQGNHDKYKGLFSSVFGLGYKSTKINGVKFILIDNSNYYGLGGTQKEWIKTEVAECKT
IMCITIMHMPLNNPTSAHIMGEYEDSAANDGKWLKELLVANGIKETESGHVHRFETYTLE
GIKTNLVGAAADSRFSEFTVKSSREIVKEEIQL
>A0A644V4A7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKINLINIIKDIIGTVFFAFILFFVAYISLNLFINVNIYLLFSISILLSLIYIFSSFYEK
KESRRITQLLLEFSHLLLWFSLMYLILSVAIYIILFIIKIPLIYLAIIYLTIIPLITIYG
YIKANKIKIKEHDLFIKNLKEEINIIHFSDVHIGSLRGERLLKDIVSKINSIDADIAILS
GDLADGTCPIEVGDFLPLSDSKIPIIFTPGNHDYYPGLENVIKAAEAANLKVLFNDKLEF
KGVSIHGFFVSSVLKPGVDIENTTDFSMINPNDINIIINHYPVFWKEFKDMGVDIQLSGH
THGGQFYPIRFLIRLMFKYVRGVFKEDDSYLVVSDGVGTYQSTIRWGTDAEILLLRLKKK
I
>A0A644SLS8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKQSFLMLFLCAAFSFAQQQATGYVFEDTNKNGLKDRKEIGIANVSVSNGVDVVKTDEAG
KYTLPVENDNIIFVIKPANYATPKSNTQLPQFYYIHKPEGSPKDMKYAGVKPTGKLPKEI
NFPLYAQKENTQFKVLVFGDPQPYDEKEIDYFRRGIVNEVKNNKKDAVFGISLGDLVGDD
LSLHSLYIDAVKEIGLPWYNVMGNHDMNYEAKEDKLSDETFEANFGPNNYAFNYGNVHFI
VLDDILYPDPRDGKSYWGGFRKDQLDFVENDLKNVNPNQLIVFSFHIQLTPENDGDKHFR
MEDRKRLFEILKPFQNVLMMSAHTHKQTQLFYGKKEGWEGIKPIHEFNAGTTSGDWYSGT
VDELGVPKSVMRDGTERGYSFVSFNDNQYEITYKVAGKPEDYQINLWVPKVIPFKTKNAA
RIVANFFMGSKHDKVEYRIDNGEWKEMDYTESIDPDYTNDVLKWDTTQELFTGRRPSNPE
ASKHIWTAPFSRKLELGTHEVEVRAKDRYGKTYTAKSTFEVKNSTLIP
>A0A644U1S8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MNNFSRKTGLFCVAILSLFAVSGLRAQQLSFRKDGSFKIVQFTDVHYCVSKPESKEALAV
INETLDAEKPDLVIFTGDVVTEAPAKNGWDVVTEAVSKRGIPFAVTLGNHDDEQDLSRAQ
VARLVASYPKSLFKDTTDNVSGYGNYTLPIKSAAGNKTAAVLYCIDSRSYSKIKAVEGYG
WFSQDQVNWYRNQSADFTKQNGGKPLPALAFFHIALPEYNKAYNTRAIGLRFEDECNPKV
NSGMFTAMLESGDVMGTFVGHDHDNDYIAWLDGIALVYGRFTGGKTTYINIENGARVITL
QEGEAAFKSWIRLRRNRIIQQTEFPKTFIKK
>A0A645A496|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKRNKIATFMAVTILCLASCNNRNQESHLNPFDNISISENINRDKILIISDLHLGNDLSY
SETVTHLERLKEFLKEVRSSNTVKELIMNGDILDEWYIPTRSDTYSGGTQADFVRKSVES
NKEIFDELNSIIRDGKIKVTYIPGNHDMGFTPENIDIAMPGVNQARDTDGKFPLGTYNPE
DYPQIAIEHGHRYDFFCAMTPGANESDAPGAILAPGYFFARIAANSFVNPTTPEAATKVP
EVKLNDAGNPEQMSKYIYYGLWKTVIENVIYVKDDFSEPIIITNLGNYTKTYSINDIIPR
NNPLTGKIEMNLYDGLFTQDNWDSRAKYNNVPVMTKIDTAIVGSLKTKFIDDMSQLQYFD
NSSSDTRIVVFGHTHKPMIKSSTNSKGEICIYVNSGTWEDHKTRDKYEVVDQDTINMHFV
LITPTKAGHNHLQIGLYQYRNGNHFKAEAMELSL
>A0A644U4F9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MPTFFIIIFSVYLLGNAYIFYKGWQVIKTFPTAGKIAAVTAFWFMALAVFGVFLLRDLNL
PYQLMHWIHLLGTGWLVFTLYMVMLLLLLDILHLFKLRIKHSFLYATALISMVLAYGCYQ
YKHPETNVINIVINKPAKSYQQLKVVAISDIHLGYGTDKEQLKDYVDLINEQRPDLILIG
GDLIDNSLHPVLDQRMEEELNLLHAPLGVYMIPGNHEYISGMEASRDFIAKTSIVLLQDS
VVTLPNGIQLIGRDDANNRKRESLDSLAAQVDPSLPVIMLNHQPFELDKAVDAGIDLQFS
GHTHRGQVWPMTLVVDRMFELSHGYKRKGNTHFYVSSGLSLWGPPFRIGTQSEMVVFNIT
FSQADKG
>A0A850K615|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrionaceae bacterium|TrEMBL
MKVTSSSSDGSIKLLQITDTHLFEATDGSLLSVNTGDSFNAVVNAILEQQCEYDAVLATG
DISQDHSEVSYQRFERGIAPLEKHCFWLPGNHDFKPNMTSVLPSQQIQHIEHVLLGDHWQ
MILLDSQVVGVPHGRLSDQQLALLEEKLTQHADRHTLILLHHHPILVGSAWLDQHTLKDA
QDFWNVVDKHENVNAILCGHVHQDMNVMHNNVRVMATPSTCVQFKPNSDDFALDTRSPGW
RELDLKPDGQVETLVKRLPQGSFQPDFNSAGY
>A0A7R9NB16|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Methanoperedenaceae archaeon GB37|TrEMBL
MVKDEKIKIAHVSDLHITGPNFVSQWGENVIDILNSEMPEILIITGDLTDDGYVHEYELA
KTYIDRIKVKNKIVVPGNHDARNEGYIIFEEIFGTRCPYYENEKVVILGIDSSQPDIDDG
HVGRENYGLHKRKIINKQQGKNTGHASSPYSYPWNRKGEKHTLRCRGCSKDLYGVGSKFC
FFRP
>B1FTT7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia graminis (strain ATCC 700544 / DSM 17151 / LMG 18924 / NCIMB 13744 / C4D1M)|TrEMBL
MSSHPFDPSRRGALKCLAFGGAGTLFVLAGGVLAPVQLALAADGKPAAASGVPLFLQISD
THIGFNKEANPDVAGTLKQTIEFVNAMPVKPALAIHTGDITHLSKASEFDLAAQLLSGLP
VTELHTVPGEHDVTDGPGAEYFQRFGKASNNRGYYSFDHQGVHFVGLVNVMHFKPNGLGS
FGDEQLKWLENDLKARSSSTPIVVFAHMPMWTIYEPWGWGTGDAGEALSYLKRFGSVTVL
NGHIHQIVSKVEGNVTFHTARSTAYPQPAAGQGSGPGPMKVAEDQLPRMLGVTSVTIARH
PLSATLADATLVS
>A0A7J0A7G7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacteroides acidifaciens|TrEMBL
MKIQYMSDLHLEFRENSRYLKHNELPVTGDVLVLAGDIFYLRDRIAPMMKFWKWASDNYR
QVLIVPGNHEYYNYSDVMERGLQWKWMFRENVGFYQNQVIRIDDTDFVLSTLWSRINPND
EYFVWKGMNDFRQIKFDGKLLQVEEFNRMHETCIDFIRKSVEESTAGHIVVVTHHLPTLE
VIDPQHKNSVLNSAFASEYGDWIANSRIDIWIYGHSHTNIDTEIGSTKVICNQMGYIFAN
EHIVNGFDSKKHVEI
>A0A3V5UU64|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Eastbourne|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>G8LEK9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter ludwigii|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFVGD
HWQILLLDSQVFGVPHGELSDFQLDWLETKLSAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVQNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHPDGLLTTEVCRLTGAKFRPDTASEGY
>A0A5I1AZ03|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Reading|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2G8X1A2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter baumannii|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIQQILKQHPEADAIIHT
GDLAQAPTPITYKRYINFMQTLGLPFFQTLGNHDNVDHFPLHNENHQQPVVVGLGNWRVI
MLNSAVKGKVDGHLSSEQLENLANLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFQNVKALVCGHVHQDSLNIWQGVEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLNNDGSFETKVFRLENFKTRINTDISGY
>V5VIX7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter baumannii|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIQQILKQHPEADAIIHT
GDLAQAPTPITYKRYINFMQTLGLPFFQTLGNHDNVDHFPLHNENHQQPVVVGLGNWRVI
MLNSAVKGKVDGHLSSEQLENLANLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFQNVKALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLNNDGSFETKVFRLENFKTRINTDISGY
>A0A653K6E3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter proteolyticus|TrEMBL
MTFQVSSLSQQDFVMIQITDTHLLEYPHLEFVGMQPEQSFHAVIDLMRQQHPHIDLIVHT
GDLAQSPTPLTYKRYVQHMQSLGIPFFHTPGNHDDATHFPFHEVDHTQPTVIELGQWCII
LLNSAQPERIDGKIAEVQLQQLTQLLTQLHDRHVIIACHHHPFAMQSAWIDQHKLKNSSD
LLETIQPFSNVKAIVCGHVHQDSINTWQGIEFLSTPSTCIQFKPKSDKFALDEEHPGYRF
IRLKANGELETQVYRLPTSQRMNSSEVLGYD
>A0A089PIW3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pluralibacter gergoviae|TrEMBL
MESLLNLPLAGGTRGRILQITDTHLFAQKHETLLGVNTWESYQAVLAAIRNSQREFDLIV
ATGDLAQDHSAEAYQHFAEGIAGFTHPCVWLPGNHDFQPAMYSALQNAGISPAKRVLVGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLADAGERYTLLLLHHHPLAAGCSWLDQHSL
RNAGALDGVLSRYPNARNLLCGHIHQEMDVDWNGRRMMATPSTCVQFKPHCANFTLDTIA
PGWRWIDLHPDGTLTTEVCRLDGAQFRPDTGSEGY
>A0A1J0EBA7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia rettgeri|TrEMBL
MDSQLEVTAKNSKIVRILQVTDTHLFANTENTLLGVNTYDSYQAVLGAIAKENLPIDLIV
ATGDLVQDQSPQAYQHFADGIERIPAPCVWLPGNHDYPPAMVETLRVAGISSAKQILIGD
EWQILMLDSQLQDVPHGELSEQQLEWMKQSLDAQPDRTTLVMLHHHPLPSGCTWLDQHSL
RNSHILADYLKSYPNVKTMLCGHIHQEMDVLWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELSVDEQGHRHIKTSVHRLETREFSPDLDSDGY
>A0A3S0ZRS8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium brasiliense|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKARQDAFDLIV
ATGDLAQDHTLQAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSAVLDRYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A8E1QK22|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNEFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAEFLPNMQEDGY
>A0A5Y2SHF9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella houtenae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>C0J7Y1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia marcescens|TrEMBL
MESLFKLPVASGAAVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAIQAQRRDVDLIV
ATGDLAQDHSQEAYRHFAAGIAQLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLLGD
NWQVLMLDSQVFGVPHGELSEYQLEWMERCLQAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAILLRYPKVNTVVCGHIHQDLDLEWQGRRLLATPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A5E9PD15|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter seifertii|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIKQILKQHPEADAIIHT
GDLAQAPTPVTYKRYINFMQTLGLPFFHTLGNHDNVDHFPLHNENHQEPVVVGLGNWRII
MLNSAVKGKIDGHLSSEQLKNLANLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFKNVKALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSKDFALDQNAPGYRY
IRLNNDGTFETKVFRLENFKTLINTDISGY
>A0A7W2ITD2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio marinisediminis|TrEMBL
MKVTSNTTVKDTIKLLQITDTHLFEAEDGSLLSVCTSDSFNAVVDAVMQESFQFEAILAT
GDISQDHSDASYQKFAQGIQSLIQPCYWLPGNHDYKPSMNSVLPSEQIVQAEHVLLGEHW
QMVLLDSQVEGVPHGRLSPQQLDLLDSKLRQYPERYTLVLLHHHPLLVGSAWLDQHTLKD
SEQFWQIVEQHSNVRAILCGHVHQDMQKERSGATVIATPSTCVQFKPNSDDFALDTCAPG
WRELELHSDGRFETRVKRLEEGVFAPNFDSNGY
>A0A0W7TX00|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas schubertii|TrEMBL
METERLQAPDGCVRLLQITDTHLFANPEGQLLGVRTADSLAAVLERVQGSDEPFDLVLAT
GDLSQDHSAGSYQRFAQMMAPLGKPIYWLPGNHDDGPLMNQSLFEAGISEAKWLVGEHWQ
IILLDTQVRTKPHGVLADHQLAALDRALRTHPDKHALIALHHQGVPVGCAWLDQHNLKNA
DDLFAVLARYPQASAILFGHVHQEFDEVHRGVRLIATPSTCIQFKPLCDDFTLDESGPGW
RYLTLHPDGRIDTQVWRLPAGSFVPDSQARGY
>A0A6S7AQF8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter deleyi|TrEMBL
MLIAQITDLHMRTPGDKAYGIIDPAAFLGPAVRALNALTPRPDCVLITGDLTDLGKPHEY
QALRDQLQALEIPYFLLPGNHDDRAELRAAFPDHGYLQGQGPFIQYAVETYPLRLLALDT
VVPMKSHGELCADRLGWLAARLAEQPGRPTLVLMHHPPFVTGIEHMDAIGLLAGAPELEQ
IVARYPNVERVLCGHLHRTIFRRFGGTIASTCPGTAHQLALELGERPTLQYIMEPPGYQL
HWWHDDALVTHHAVIGEYPGPYPFA
>F4HBC5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gallibacterium anatis (strain UMN179)|TrEMBL
MSDLFRDESAGVIKLLQVTDPHLFADEDGELLGINTFDSFRQVLSEIKKSGFESNYILAT
GDFVQDNSEAGYHRFVKEIVQLGKKIFWIPGNHDFQPKMEAVFDLYKAVIQPEKHLLLGE
SWQVILLDSQLYGVPHGMLSEEELKWLEQRLSLYPDRNTLIVLHHHLLPTNSAWLDQHNL
RNPYDFSEILAKHKNIKAIVYGHIHQEVNAVWQGIPVFATPSTCIQFKPDCAYFTLDNLQ
PGWREISLYPDGRLETKVHRIKDKVFLPKDNMNGY
>A0A643ECW0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas aeruginosa|TrEMBL
MSRHSNTPATDASVLLVQLSDSHLFAEDGARLLGMDTAHSLEKVVERVAREQPRIDLILA
TGDVSQDGSLDSYTRFRRLISPLDAPLRWFAGNHDEREPMQRATEGSDLLEQVVDVGNWR
VVLLDSSIPGAVPGYLEEDQLELLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGY
RWLRLHDDGRLETGISRVDDVVFEVDYDTAGY
>A0A1Q9NNF6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Heimdallarchaeota archaeon (strain LC_2)|TrEMBL
MKLVMFSDPHIDIQEKRGYPKFLVQLNEYLESIEPDIILVTGDIAGSTSYIQKFLEGIFT
SAKKKIYCPGNHDIWVNSKAHDASWTKYYQILPQLSTELGWHYLPNQPLIVNNVAFVGTM
GWYDYSTRNPIWDDKISILEYSSKYNKSSGAIWMDREYAKFGDHNDNVVADHFANELIED
LQSISDNLIEMNWDSGNSSIEELNKYNKLKKLKKLESKNVDTVVIGTHMVPFVDFVKFTG
NLDWDFFSAFIGNTKLGRIIKSINNELRRISVFGHTHYPQRKIVEDNLEAICCPIGYPNE
WERDHSSLESLFESKIVSVNI
>A0A854D2T0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus parainfluenzae|TrEMBL
MNNTFECKPASEIVKLLQITDPHLFKDTSKDLLGINTHESFSQVLKEIQAESFDYDVVLA
TGDLVQDSSDEGYLRFIEMVKPLNKSVFWLPGNHDFQPKMVEHLSQSPINASKHLLLGKH
WQVILLDSQVSSAPHGELSAYQLDWLKMKLAENPARHSLVVLHHHLLPTNSAWLDQHNLR
NAHEFSEILSQFNNVKGILYGHIHQEVDGYWLGYQTMATPATCIQFKPDSNHFALDTLQP
GWREIELYPDGRIETRVKRIKHKTFLPNMEEEGY
>A0A410SIG8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus parainfluenzae|TrEMBL
MNNTFECESASEIVKLLQITDPHLFKDTSKDLLGINTHESFSQVLKEIQAESFNYDVVLA
TGDLVQDSSDEGYLRFVEMVKPLNKSVFWLPGNHDFQPKMVEHLSQSPINASKHLLLGKH
WQVILLDSQVSGVPHGELSAYQLDWLKTKLAENPARHSLVVLHHHLLPTNSAWLDQHNLR
NAHEFSEVLAQFNNVRGILYGHIHQEVDGYWQGYQTMATPATCIQFKPDSNHFALDTLQP
GWREIELHPDGRIETRVKRIKQKTFLPNMEEEGY
>A0A7C8CEE1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rouxiella sp. S1S-2|TrEMBL
MESLFKLPLVDGAKVRILQITDTHLFAGEDQTLLGVNTFRSYRAVLDAICAQQREVDIIA
ATGDLAQDQSLEAYHHFSRGVNRLPAPCVWLPGNHDFQPAMVNALAEAGIHPSKQVLLGN
DWQVLLLDTQVFGVPHGEISEYQLEWMTRCLDAQPERFTLIMLHHHPLPSGCTWLDQHSL
RNAHTLANALQAYPKVTTLLCGHIHQEMDVDWYGKRLYATPSTCVQFKPHCTNFTLDTVA
PGWRYLTLHPNGRVETEVCRLETNEFSPDADAEGY
>A0A1W4UA64|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila ficusphila|TrEMBL
MRNCLPKFSKVFRRKSSAKSSSTGGLGRENPSNEPDSDTEPYAIAAIADRGGDNRNERPL
PDDDSSRRRLISVAHLNSDSDLPANGKGVPFSQHRSTDEGSCPEMKVETISTTTATTADS
VPLASGQAAISQPFAGRNSSKTPEEMELEYEATVEAESRDIMTPLRRNTRPLSVSFGAGR
TALQPEIVEAIRSLDVPALLLNNLNLDGGRGAEVETRSQSHSQSQSGEMSPGHELEDSVV
LRRKVNCLERKAHSLYERRLPKVPKLHLLVAGKKSKADEEREAEAEELRTFQRNLMDLKY
PTVLPPNPPLKALLVFHKSDSICEAVTAACQRHQLDVTLVKSKEEALDTLQKSYATAQCY
HLIIIDARSTKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCV
AETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRAT
ERLLNMRLDEIISKQLEDIFVSDLSTISEQCKSIKEFDGILTVRRKSQEGIPMHVRVVPV
ACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTS
LAKLTSLPLEAPITKENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGAL
LTVTKGPSVYSSRRSSNDSIIRTGSSTRTASIVPAKMKSNPIIMELLDESLSWDFDIFKL
EEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVM
QATGAFITQLTNKDMMMMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLT
VLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSV
FGGEEPRDHNSQTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEK
QRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMIHAWESFIDMPQLITYMQINYSQWKKY
DEQGVNTLAEIMAKQPPVGKMANSK
>A0A8F7MWF5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas amygdali|TrEMBL
MPSAAPSSSVLLVQISDSHLFAEADGALLGMSTRNSLEKVVDLVLAEQPHIDLVVASGDI
SQDGSVESYEAFRRISTQIAAPARWFAGNHDELPQMEHVAQAEGLLDPIINIGQWRVTLL
DSAVPGSVPGFLAAGQLQLLEQSLSEAPDRHHLVCLHHHPVAIGCEWMAPIGLRNADALF
AVLDRFPQVRAVLWGHVHQEFDQMRNGMRLLASPSTCIQFAPGSADFKVDTTAPGYRWLR
LHDDGRLETAVSRVVGMEFEVDYGGTGY
>A0A446CKR3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter agilis|TrEMBL
MSKFDEAKGQQAVTPSVPTRRTFLRGGLAAALIPGAGLLTACGGGDDDDDGDDAPVTGET
PQPGPIEDSSKGSRFALAVLPDTQFYARYATVAENSQYSRKFGSEPFMAQTYWIAANAAA
LNIPFVTHLGDVVDQASKPDQWKVADQAMRVLETAKVPYSVLAGNHDVLQSLEYVDASSQ
SSGTDAQRNLGNEPYLQWFNTARAKRMSTFGGRDTTGFHEYHVFEAEGQKFMVLSLSWRI
SDDGIAWARRIIGENPGLPVILVNHQLLNIDRDGVSPLDTEYGNMLWERLIRDNDQIFMT
LNGHHHGAAHRTRTNDFGNKVELMVVDYQMAYQGGNGLMRLYEFDLTHNKIHVLSFSPWV
VQKPRDTLTQFDQAVLKTGNEQFSIDMDFASRFSGFNKTFGPSSELRASLVDAASAMILA
GYTEPDVAASRAPVDTEDYPKVGSTVAHWRFVGGAAGQTVAAGQVIEDRAGLNPLRRAAL
NSEAGVQAAQLDDLLWTSDKHYLSAAPGSVRFANTDKNAKRLSYFLTEASAPLNAMDFAG
TGYTVEAFVKIDKDWSSSLHAWMNIMTRDGRRDTIPGFSGGDGESPPLLFAVSSLREIQW
EVVTPQAGTRSPQASWSGEIMADSWVHIALVADPAAQESIMYIEGAPVLRNSGNASGLAS
VSAAMPWVVGAGSWDGERADGFLGNIGEIRIASEPLPSSQWLTARRS
>A0A7G6AL61|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter baumannii|TrEMBL
MTFQVSTLSQKDHVIIQITDTHLLEYPHLEFVGMNPEESFHAIIQQILNKHPEIDAIIHT
GDLAQAPTPITYNRYIQYMQTLGLPFFQTLGNHDNVDHFPLHKENHQEPVVICLGNWRVI
LLNSAVKGHIDGHLSAEQLENLTALLEEYADNPILLACHHHPFAMKSKWIDHHKLQNSNA
LLTTLAPFKNIKALVCGHVHQDSINTWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLKNDGSFETQVFRLENFQGHINTDISGY
>A0A3N2EGK5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Raoultella sp. BIGb0399|TrEMBL
MESLLNLPLAGETRVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFAVPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGQ
HWQILLLDSQVFGVPHGELSDFQLEWLEQRLAEEPERYTLLLLHHHPLPSGCSWLDQHSL
RNAGALDRALTAFPRVKHLLCGHIHQELDLNWNGRRMMATPSTCVQFKPHCANFTLDTIS
PGWRWLDLHADGTLTTEVCRLKGVKFHPDIASEGY
>A0A0D1GHY7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio parahaemolyticus 901128|TrEMBL
MQSSNDSIKLLQITDTHLFAADEGSLLSVKTADSFSAVVNEVLRRKVGFDYILATGDISQ
DHSAESYQRFADGIAPLQKDCYWLPGNHDYKPNMGSVLPSPQIQAAEHVLLGEKWQLILL
DSQVVGVPHGRLSDQQLTLLEEKLTEFPERHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFDNVKGILCGHVHQDMNVIHKGIRVMATPSTCVQFKPNSDDFALDTTSPGWRELE
LHTNGDITTHVDRLPEGQFQPDFSSNGY
>A0A8G1V3E6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea ananas|TrEMBL
MDSLLTLPAATESGVRILQVTDTHLFAGKHESLLGVNTWSSYDAVLDAIIAQQRDYDLIV
ATGDLSQDHSVEAYQHFVEGISRLPKPCVWLPGNHDFQPAMVDTLARAGINAHKHVLVGE
HWQVVLLDSQVFGVPHGMLSDYQLDWLDNALARFPLRHTLVLLHHHPLASGCTWLDQHSL
RNPHQLDAVLQHYPLAKTLVCGHIHQEMDMAWHGRRVLATPSTCVQFKPHCTSFTIDTLA
PGWRWFTLHNDGQLDTEVNRLTTQAFCPDLDAEGY
>A0A8A4K8F4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea ananas|TrEMBL
MDSLLTLPAATESGVRILQVTDTHLFAGKHESLLGVNTWSSYDAVLDAIIAQQRDYDLIV
ATGDLSQDHSVEAYQHFVEGISRLPKPCVWLPGNHDFQPAMVDTLARAGINAHKHVLVGE
HWQVVLLDSQVFGVPHGMLSDYQLDWLDNALARFPLRHTLVLLHHHPLASGCTWLDQHSL
RNPHQLDAVLKHYPLAKTLVCGHIHQEMDVEWHGRRVLATPSTCVQFKPHCTSFTIDTLA
PGWRWFTLHNDGQLDTEVNRLSTQAFCPDLDAEGY
>A0A3R8NAL3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium aquaticum|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKARQDVFDLIV
ATGDLAQDHTLQAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALAEAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSAVLDRYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLSDGRLETEVYRLSGSEFLPDMDSDGY
>A0A557SCW1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sedimenticola selenatireducens|TrEMBL
MTPDIISIDSQAKERAQQDKTLRILQITDSHLHTDPEWRLAGINTQTSFEWVMDLVQQEA
DTIDLLLLTGDLVHDASITGYTRLRQHIQRSGIRASCLPGNHDKPETLRMHLAGERVDVP
KVVDLGTWVLILLDSTIPHSEGGHLSDQELELLQQSLNNYADRHILIALHHHPVKINSAW
MDKMSLDNPAPFLAILEQHNNVKGVVWGHIHQTFEAVHNGIRLMGTPSTCIQFVENQDKF
GISTAPPGYRWLELSPDGLINSGIERVEALPPGLDLKTAGY
>A0A7U7IKJ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pneumoniae subsp. pneumoniae Ecl8|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A6P0YCQ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Okeania sp. SIO1H6|TrEMBL
MISQSPVLVAQITDTHLFADPTQGTMYGLPTESSFVKVLEKLKQLQPQPDVLLLTGDLSQ
DETSESYQRLASLLSPLNIPTYWIAGNHDNLPTMERVLNSAPISAKKSFEMGGWNFFLLN
TNVPGLVYGEISPESLEWLEYNIKMTGNKPVLIALHHPPVKINSEWMDKILLHNPENLLN
IINRYPQVKIVLYGHVHQEFAKEINGIHYLSTPSTCIQFEPGNPKFFLDKQPPGLRLLTL
YPDGNYITKIERADYIYECDMAATGYSSTTNN
>A0A368NP64|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Corallincola holothuriorum|TrEMBL
MLPEGRVCPQLLQITDTHLFGSPEKSLLGVNTRDSFHAVLDLIEQQPAEIDAFLATGDIS
QDDSISSYSAFAHGIARFAAPCYWIPGNHDDPRIMATELDNPTLHAAKQIVYPKWQVLLL
DSQVKKHTYGFLSESQLLFVEKAVAEYPDRHCLVLLHHNPIPVGCRWLDQHQLKNGSQFL
DLLSRLPQVKGVVWGHVHQTLDRMHNGIRLLSTPSTCIQFKPNCDQFTLDTVAPGYRRLT
LLDDGEIDTEVLRLKDNPFAPNLASKGY
>A0A0J5IMW4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus khoisanae|TrEMBL
MESLLEIPVAEGATARILQITDTHLFANKGDSLLGINTYRSYHAVLDKILEQNLDIDLIV
ATGDLVQDQTINAYQHFAEGIARLPAPCVWLPGNHDYQPAMVDTLAAAGISPSKQIFIGQ
HWQLIMLDSQVQGVPHGELTDYQLEWMNKCLDEHSERHTIVMLHHHPIPSGCTWLDQHSL
RNAPELSEFLKGKAQVKAILCGHIHQEVDEMWNGIRVMATPSTCVQFKPHCTNFMLDTVA
PGWRYLELSVAGNEETRLQTQVHRLKSNEFCPDLDSDGY
>A0A519F707|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp|TrEMBL
MSSPSSHSSSVLVVQLTDSHLFAEAAGTLLGMPTRASLDAVVERVLIEQPAIDLVLATGD
LSQDGTVESYQAFREASERLNAPARWIPGNHDELREMAIAAQNSDFLEPVVDVGSWRVTM
LDSAVSGSVPGYLQDGQLQLLAQALSEAPERHHLVCLHHHPLPIGAAWMEPIGLRNPEAL
FSVLDRFPQVRAVLWGHVHQEFDQLRDGVRLMASPSTCIQFAPNSVDFGLDDLAPGYRWL
RLHDDGRIETGVSRIEPDLFDVDINGAGY
>A0A8G1E2Z5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas germanica|TrEMBL
MPSVSTLTSADTALLVQLSDSHLFAEADGKLLGMNTRESLQKVIELVLGQQPQIDLILAT
GDISQDGTLESYQQFRQMSAQIAAPARWIPGNHDEPMIMAQAAVQSALLESVVDIGNWRV
TLLDSAVPGSVPGFLQDDQLQLLVRSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
TFFEVLDRFPQVRAVLWGHVHQEIDRERNGVRLMASPSTCIQFEPGSVDFKVGEQAPGYR
WLRLLPDGRLETGVERVTGFAFTVDYGSNGY
>A0A844PB60|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aliivibrio fischeri|TrEMBL
MLSETLLNEESDSIRLLQITDTHLFAPEDGALLGVPTRKSFQSVVEQVLQRTPDFDAILA
TGDISQDHTVESYQHFVKGITPLKKPCFWLPGNHDYKPSMGGVLPSPQISACEHLLIGQH
WQVIILDSQVVGVPHGALSDEQLTLLDNALSQHPQRHSLVLLHHHPLPAGSAWLDQHQLK
ESDQFWSVLAKHRNVNGIVCGHIHQELDRIVNGVRLLATPSTCVQFLPDSDDFALDSQAP
GWRTLDLLPNGDIETQVHRLKNCDFSADSEAGGY
>A0A1E5E260|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio rumoiensis 1S-45|TrEMBL
MKIIEPNLDDVTLVQITDTHLFSDSDGELLGVNTLSSFSAVVNDVLESGLEYHSVIMTGD
VSQDHTDASYSRFEQGILPLKKNCYWLPGNHDYKPSMRSIYPSTQIQEDTYLQVGKSWQV
ILLDSQAEGSPHGFLSQQQLEYLDSTLQQYPERFTLVLLHHHPLLVGSQWLDKHCLHNSE
VFWQVIEQHQNVKGVLCGHVHQDFHQVHLGVEVFTSPSTCIQFKPNSSDFALDKVSPGWR
SLTLKSDGSIATQLHRLTGEQFLPDFDAQGY
>A0A2H5V7B4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|archaeon HR03|TrEMBL
MERLVHISDTHISRFGMFLPDRLDACIRIVNSLDPAPQFVIHTGDLTDYGILMDYEMAVE
KMDEFEPDIIYVPGNHDEKNYGDSLFREMVSQVDVLNSFGKIVVLTLGSAIPDSDNGRLG
RGRQQMIKQRMQGFGDDILKIVAFHHHLIPVPFAGREKDILEDAGDVLRIILESGVNMVL
MGHRHVRNAIKVGETLLVNAGTVSCVRTRGRLGNSFNIIDLYSDGSVEVSEVGIPAGEAR
SIGRFTVMRGRL
>A0A2I0YYN3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lactiplantibacillus plantarum|TrEMBL
MQYFTSDTHFYHADLLGDNDFAPRLFPDVETMNQAIVDHWNARVTDQDTVYHLGDVALYF
TRPAKLSYERVFALLAQLNGKIIFIKGNHDSRAFFKYLAAHDPQLNGQPKFEFHDVGVLI
KYDHRQYYITHYPMMMGIVKQIINLHGHIHHYAVNVKENINVGVDTPEVDYLDHPVPFGT
PFSLAEIEQMVDGKAIDFAKRQ
>A0A2H5V673|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|archaeon HR03|TrEMBL
MLAGSAAFFITDNSQRLDKTVIDIGLGAKAVFLPDLHIHSENIQTSQLLSVLDREEPDAV
VLGGDMVDELTTDLGYVRRFLSELPGSEKFFVLGNHDYWSGYDEWLRENLRAMGYREVRS
VAESRYLGKIHGIDWRDNRSYEPFKANGLVFAHDPHVADSVSGDCLIFAGHTHGGIVING
VTLLSNSRYTRGWYSWGNKRLYVSRGLGQMLAYRPTSPRELVVLV
>A0A3L8B6Q7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ketobacter sp. GenoA1|TrEMBL
MRIVQLSDCHLFKSTEGKLLGLNTEQSLALVMDLIQDQQHAIDLVLATGDLSQDGSSESY
ARFHQWMEAFSCPVYWLPGNHDLTDIMANHQAAQRMSPCVIDAGNWQIIMLDSTIRGKVP
GNFAASELQFLQQALQASTGKHVLIALHHQPVPVGSAWLDQQIVGNAAEFFKVVDQFTNV
QAIIWGHVHQVFETRRNGVQLMSVPSTCVQFLPNSKDFAVDKTSPGYRWLDLHADGTIGT
GVSRVTGVDFVVDYSVKGY
>A0A6S6ZUU5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter kerstersii|TrEMBL
MSAIFVHISDIHFGQEKDQRVHIHNDVKKQLIVDAKRVVKDHLKANAAAILVTGDIAYSG
VEEQFKVAGEWLDALAAAVGCPQNQVQMVPGNHDLDRNKTSRSAQHLLDLIRAGGPADYE
EVMNNSTDRAALFARFEDYERFCWGYRCELNGEAKAATNLQITLAPGRSIRFIRMNSSLL
CTGKERDDEPELVLGERQFIIDRDDGVENIVLIHHPLNWYKDSGDVKTYMDSRARVLITG
HEHHPNVTVKQVGEDADLMMLAAGATVPFKSNEVYTFTYNVIEFEWDPDDDDLIVTMHPR
AWDPKGTCFVADNKRLGGAQPQYKVRCPNFKLAPRPPVVEEEAKAAAGGAATGIASPPLV
ELVPAEVDEGEVAEMPPTVEGYGPIELRFFRDLLEGERLRILITLDAVPHDSDERMNRGL
QRKLLEWLAREGKLSDVERLMNEYMEERTKKET
>A0A8C3TS80|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Catharus ustulatus|TrEMBL
MVTQAALCVLCSVRSFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSD
SDYDLSPKTMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNK
>A0A5W7RNZ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Kintambo|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A1V3KWW9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rodentibacter ratti|TrEMBL
MKNTFVYQTEKPIVKLLQITDPHLFKDEENELLGVNTQASFAQVLKEIQQENTEFDAILA
TGDLVQDSSDEGYQRFVNMVKPFGLPVFWIPGNHDFQPKMVENLNQPPMEKAKHILLGKY
WQVLLLDSQVYGVPHGELSQYQLDLLKTTLEKYPEHHTLVVFHHHVLPTNSAWLDQHNLR
NSHDLFDVLSAFKNVKGILYGHIHQQVDSFWQGYQVMATPSTCIQFKADSQHFALDEAQP
GWREIKLHSDGSIVTTVKRIRQAVFLPNMQEEGY
>A0A1A8IPE4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothobranchius kuhntae|TrEMBL
DWCLDQLETIQTHRSVSEMASNKFKRMLNRELSHLSEMSRSGNQVSEYISTTFLDKQNEV
EIPSPTLREREKPMCHISGVKKLTHSSSLSNSTLPRFGVKTEHEEALARELDDLNKWGLN
IFHVAEFSNNRPLSCIMFAIFQERDLLKTFRIPVDTFVTYVMTLEDHYHANVAYHNSLHA
ADVTQSTHVLLSSPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYND
ESVLENHHLAVGFKLLHEENCDIFQNLSKRQRQSLRKLVIDMVLATDMSKHMSLLADLKT
MVETKKVTSSGVLMLDHYTDRIQVLRNMVHCADLSNPTKPLPVYRQWTERIMEEFFRQGD
KERERGMEISPM
>A0A7Y7YXX7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. P7759|TrEMBL
MPSVSTVSPDAPALLVQLSDSHLFVEADGTLLGMNTRDSLQGVIERVRAQQPRIDLVLAT
GDLSQDGTLESYQQFRDMTRQIDAPARWIPGNHDEPQIMAHAAVHSDLLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPNRHHLVCFHHHPVPIGCAWMDPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERLVGFAFTVDYGSNGY
>A0A2J8LWF1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pan troglodytes|TrEMBL
ETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVS
EYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGVKKLMHS
NSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQAVFT
DLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNC
DIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKT
>A0A2J8LTB1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pan troglodytes|TrEMBL
MTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERDLSPRPELRKSRLSWPVSSCRRFDL
ENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASD
LHGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAK
>M7BU76|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chelonia mydas|TrEMBL
MDPLELAVSPVKRLRTEYSFPYLFAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKKQDHAGKAFDMRYTVSWVVIANLKVNQNDAISYVRTGN
>A0A5X7WE56|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella montevideo|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDVDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A264TEV0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium sanguinicancri|TrEMBL
MQTYTLPQQGPDKVVLLQITDTHLFNDISGSLLGIETKKSFHAVLDAVDDAARPFDAIIA
TGDISQDHSENSYQRFADGISRWTQPCFWLPGNHDYQPTMRSVLPSPQIKPCEQVLAGEY
WQVILLDSQVPGVPHGALSSAQLEMLDSALSAHPERHALVLLHHHPLEAGSYWLDQHQLH
NNEALWYVLDQYPQVKAVLCGHIHQELDRMYRNVRVLATPSTCIQFLPDSNDFALDQVNP
GWRYLELYANGDIRTEVSRVQGPQFAPQFDEAGY
>A0A564FTT3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium dankookense|TrEMBL
MHDPTDSDGDPSRPSRRGALECMAWAGTGLLWTLGGGLPRAVGLERALAAEAAPAPFSFL
QISDSHVGFSKPANPDALGTLREAVERIRALPQKPAFIIHTGDISHLSKDGEFDDADQIL
RETGLPLFFVPGEHDLLDDEQGRAYLARYGKGSRGAGWYSFDQGGIHFIGLVNVVDLKAG
GLGNLGAEQLDWLEADVAGLASSTPVVVFAHIPLWTVYPEWGWGTQDGARALALLRRFGS
VTVLNGHIHQIIQKVEGNVAFHTARSTAFPQPAPGSAPSPGPMKVPAGELRRHLGIASVT
LVRGSEPLAIIDTPLAG
>A0A7X5SJZ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas allosaccharophila|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQANEHHYEVILAT
GDLSQDHSPESYQRFASMMAPLGRPIYWLPGNHDDSPLMTEYLHAAGISESKQLVGDHWQ
VILLDTQVRGKPHGMIGDHQLAALDRALRQYPDRHALITLHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLCDGFALDESGPGW
RYLTLYPDGRVASEVWRLPVGQFVPDPDATGY
>A0A2H5ZL12|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR30|TrEMBL
MQFDVQRPLRARLEAWFFHNFFLFLLLWVSAAEAGVAWWVARQWFDLEGRSFVLSAIVVA
GFNFWLVRRRRNTQRNLVDRLPQFYHAAAFTCLFCAGFLFFNHLLWRGSSYVHAFLTAEA
RGMAPAKRPLRAGPLDERRTGWIGLCGIVGLFTYGYTIGQRRLRVQFVQVALHRWPKSAP
PFRLVQLSDIHVGANMTPAELSRFVATANSLRPDLVCITGDIADNARSDLDAYFPILGQL
RARYGVVAILGNHDHYAGAERVVRALRQHTGFVVLRDATLTIDLPHGRLHVIGLDDRGLD
WARGVPQVPQLEVLWHQLPQDEPQLVLSHRPDLFPQAARLGIDLMLSGHTHGGQIALPWF
NGQHLSLAQLITRFDRGLFRQGRSALYVNCGLGVTGQRIRLWTPREISVIELCPVANHA
>A0A3R8W4X6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas saudiphocaensis|TrEMBL
MPVQSLTAENDSVLLVQLTDSHLFAEASDRLLGMDTAEGLQRVVERVLDEQPRVDLILAT
GDLSQDGSTASYELFRTLCEPIQAPARWCPGNHDELAAMQQVTQGSELMAPVLDIGAWRV
VMLDTLVPGSVYGMLRSEQLELLERALQEAPDRHHLICLHHHPVSIGSHWMDQIGLHNSE
ALFEVLDRYPNVKALLWGHIHQEFDGQRNGVRLLASPSTGVQFAAGSEKFQVDTLAPGYR
WLRLHADGQLETGVSRVEGVDFGVDYSIEGY
>A0A1A8DYU9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothobranchius kadleci|TrEMBL
MLKRSWSAQGGTPSDENPDPLVGQFSSGCTLGVEACKVHRRFSGNLQLPPLSWRQAETER
DRGRPLTPEEDPVTRSRPTSLPIVSLPRIDITQADSDSLEVENAPPLCCSPSDLQASPGS
GLVLHPNMANHSQRRESFLYRSDSDYELSPKSLSRNSSIVGELHSEDLIVTPFAQVLASL
RTVRNNFTTLTNVQCASTKRSPAANQPCVTKVCLSDESYQKLAMETMEELDWCLDQLETI
QTYRSVSEMASNKFKRILNR
>A0A0N0BFQ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Melipona quadrifasciata|TrEMBL
MGCKTSMLECIEDTGEAEKRKQSNILDQGFLLGKTEYEEIIRRKSSFEGIGVDDENADCS
TLKGPQNIEAHPLTNSVPSLIKILLVFPKDDQQMDILATTSRRLGWSVSAAKDMEKAVEL
FQDRGHELVIIDHRGQRAAEADMICRAIRSSPVYHNSVIIALVKKSFLMHGEKDKIVTLD
LLETGFSKALMECSHERILINELVGIYASALVPRTQLAAANALYLALDRCRDMVHVTNDK
HIVQFVNKISEKLLGYKTSEILGKSITDIVIYDNFILMEQHISKGREFEGNMNCKRKNNQ
TITISCRVIPYSISLKKPNYYIYIYDTTYLSENIELLSPTSSLQPRETVVSQRNMSEIKL
IEGRRRSSIRKLHKLQLEAPITKVITLLSNAVMEIESPETAAQIEKAIDILQTTELYEPS
LREDTDPVTTEFVEALLSSPKKVRESRRSSVESARFFAEKNVNEVPSLHMQIKGFKNPQE
IANVLDKCLEWDFDIFKLEILTENRPLLFLGMTIMNVYRVPARLGCDEKIVQNWLTVIEM
NYKVRNSYHNSTHAADVMQATARFMQSERLKLILEPLDEVAALIAAAAHDIDHPGRSSQF
LCNSNNKLAILYNDLSVLESHHAALTFKLSLSDDSVNIFQNLERDSYKQVRQTVIDMILA
TEMTKHFEHLAKFMNVCNARIDYQHMDVYPDVVDMSVVLQPENVVLVKRMMIKCADVSNP
TRPLRSCVEWARRIAEEYFSQTDEEKKLKLPVLMPMFDRSTCSIPKSQIGFVDFIINDMI
EAWDAFIDMPEMVGYMRHNYEKWKEYNDRGLSTLLDIDKIQELPELQITLVTHGTR
>A0A4P6QCA2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas syringae|TrEMBL
MPSAALSSSVLLVQISDSHLFAEADGALLGMSTRDSLEKVVDQVLAEQPHIDLVVASGDI
SQDGSVESYEAFRRISGRIDAPARWFAGNHDELPQMEHVAQGEGLLDPVVDIGRWRVTLL
DSAVPGSVPGFLADGQLQLLERSLSEAPDRHHLVCLHHHPVAIGCEWMAPIGLRNADALF
AVLDQFVRVKAVLWGHVHQEFDQVRNGVRLLASPSTCIQFAPGSVDFKVDTLAPGYRWLR
LHDDGRLETGVSRVVGMVFEADYGGTGY
>K8WC94|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia burhodogranariea DSM 19968|TrEMBL
MDSQLEVTALNDKVVRILQVTDTHLFADTANTLLGINTHESYHAVLDAILEQNQPIDLIV
ATGDLVQDQSPQAYQHFVHGINLISAPCVWLPGNHDYQPAMVKSLKVKGISCEKEILIGN
EWQILLLDSQLQDVPHGELSEQQLEWMKSCLDKQPQRTTIIMLHHHPLPSGCTWLDQHSL
RNSHILADYLKDYPQVKAMLCGHIHQEMDENWHGIRLLATPSTCVQFKPHCTNFALDTST
PGWRYLELSIDENGNRQINTQVHRLETRKFSPDLNSDGY
>A0A3B0ITV0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arsenophonus endosymbiont of Aleurodicus floccissimus|TrEMBL
MDSLFKLTTKQKSLVRILQITDTHLFANVDDTLLGVNTFGSFHAVIDAILARNENVDLVV
ATGDLVQDQSASAYQHFAEGIKRLSVPCVWLPGNHDYQPAMVATLAKAGILPSKQVLIND
NWQILMLDSQLQGAVHGKLSKQQLLWMKCCFDAYTERSHLLMLHHHPLPSGCTWLDQYSL
RNSHILADYLNQYQQIKAILCGHIHQEIDEYWQGVRMMATPSTCIQFKPHCTNFTLDTMA
PGWRYLDLSINDNGENVLDTQVFRLDSDKFRPDFDSGGY
>V0AMH3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli 909945-2|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A2S7XFP3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aliivibrio sifiae|TrEMBL
MLSETLLKNENGPIRLLQITDTHLFAPIEGALLGVPTLYSFQSVIEQVQQRTSGFSAILA
TGDISQDHTVESYQHFVNGIKPLEKPCYWLPGNHDYKPSMGGVLPSPQIRSSEHLLIGKH
WQLIILDSQVVGVPHGALSIEQLDLLNKALTQYRTRHSLVLLHHHPLPAGSAWLDQHQLK
DNEHFWNVISKHSNVKGIVCGHIHQELDRMINGVRLLATPSTCVQFLPDSDDFALDAKSP
GWRTLDLLPNGDIDTKVYRLEDCDFSADAEAGGY
>R8AT49|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Plesiomonas shigelloides 302-73|TrEMBL
MESLFQPPVATERVRLLQITDTHLFADEEGALLGINTLQSYHAVLDAIVAEQQIAEQQPV
DLIVATGDLAQDHSLEAYDRFADGISRLDSPCVWLPGNHDFQPAMVDGLRGKGIQPSKQV
LLGDHWQLILLDSQVLGVPHGELSDYQLNWLAARLDAHPERHAAILLHHHPLPSGCTWLD
QHSLRNSHVLDEVLSSRPQAKVVLCGHIHQEMDLNWNGRRLLATPSTCIQFKAHCTNFTL
DQLTPGWRYLDLLPDGRIETQVHRLTDQRFSPDMESEGY
>A0A2I2UT86|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Felis catus|TrEMBL
MQVFMAVLFLSFFHSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDS
DYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPM
CNQPSINKATITGTKRNIFSHIPLLMTTTKHLRFGHNPGQIFYLNNIFLGVTLELHSYAL
TDLFVLLNDLQFKVRISISY
>A0A8E5TYL1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella sp. SJTUF15034|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A373B132|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. SWAC57|TrEMBL
MTLNNEKNWIIVQISDTHLMDQDHLEFVHMNPEQSFHHVMQHIVERHPKIDAIVHTGDLA
QVPVPRTYQRYLDFMQSLKTPFYQVPGNHDNIEHFPFHEQQNKAHVIHFGPWSVVLLNSA
VKGKVDGWVDEAQLIQLEQILQDFAQQHILIACHHHPFEMQSKWIDQHKLKNTPDLTAVL
ARHTNVKIVLSGHVHQESWREWHNIQFYSTPSTSVQFKPLSDHFALDEQAPGYRILQLNA
DGTHETQVQRVSHAQQKINVEISGY
>A0A6P4L9I8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila bipectinata|TrEMBL
MRNCLPKFSRVFRRKSSAKSGRENPSNEPDSDGEPYTAVIRPTALSDPPSDNHNESSPSR
LISPANTDLDLDLNLDSGVPAINGGIQGSWPEMKVETISAAAAAEATAAASVPASVAISQ
SFGGRNSGKTPEEMELEYEENVKAEGRDIVTPLRRNTRPLSVAFSGSGRSALQPEIAEVI
RSLDVPALLLNNLSLDTKNRECERETDCYDHEDSCEVVLRRKANCLERKTRSLYERRLPK
VPKLHLQVAGKKTSEEEEFRIFQRNLMDLKYPTVLPPNPQLKALLVFYKADSICEAVSAA
CQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSSKNLDAEHIARTIRHTHGHH
LTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMST
QQALYTALHRLKEVVLITDDVLRIQYANRATERLLNMRLDEIISKPLADIFVSDLSTISE
QGKSIKEFDGILTVRRKNQEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQ
PKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKENCSADEARLIDKV
LEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTATI
VPAKMKANPIIMELLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENV
CKAWLAVIEAHYHKSNTYHNSTHAADVMQATGAFITQLTNRDMMVMDRMEEATALIAAAA
HDVDHPGRSSAFLCNSNDSLAVLYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKEQYK
SARSTIIDMILATEMTRHFEHLAKFVSVFGGDESREPHAQTEEETSILMRRMLIKVADVS
NPARPMQYCIEWARRIAEEYFMQTDEEKQRHMPIVMPMFDRATCSIPKSQIGFIEYIIQD
MMHAWESFIDMPQLITYMQINYSQWKKYDEQGINTLADIMAKQPPVGKLANSK
>A0A4Q6E389|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moraxellaceae bacterium|TrEMBL
MARPGTNSKRFIQISDCHLGPLTSEALLGLNTDESLHDVLALITEKESTFDYMVCTGDIA
SAGHESCYRRFVSIVREYFSEPLAWLPGNHDSTSIMTTVDLPQIPEARAIDLDKWLILLL
DSVVPFKVHGNLEQGELDYLKQMLSENPDKHIMVMLHHQPVLVGSQWIDQYILRNDDAFF
AIVDRFPNVKAIVWGHVHQDFNSQRNGVALIATPSTCVQFKPLCDDFTVDTLMPGYRWFD
LNDDGTLTTGIERVIGKEYVIDYKSAGY
>A0A8C9PC00|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Spermophilus dauricus|TrEMBL
MSPSLPQTSATSLEPLHHPGCPFLEETCQQLARETLEELDWCLEQLETMQTYRSVSEMAS
HKVGTPLLTATPIPGARQSPQCSKQLLAPDQCTYSQQQVR
>A0A829ZCL4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|[Clostridium] cocleatum|TrEMBL
MYQYIGLIAVFPGIVYFTFFINRFIKTILNYHTNMLIILVIGLVVSMLSLPAINTLELYG
VIYYHLLVIMLILELLNIILKKFLIYRFVFTTGILAIVITALVLGYGYYNIKHVIPTTYN
LISKKISDLKIVEIADLHMSTSLTVLQLQEYCNEISKEKADIVVLTGDIFDENTPLDDML
NTCKVLSTISNKQGIYYIYGNHDNGSHAFKDIAFTPEDIRKNLEFNGIEVLDDEIVTLEN
INIIGRKDASFWGTNPRLSTVELLAKIPDDKKDNYTILLDHQPLDLEQNASLGIDLQLSG
HTHGGQLFPMGIVQSLTSDTLVRGQRNIDDFTAITTTGMSGWRYPIKTGAPSEYVIIKVK
>M1SCF4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Morganella morganii subsp. morganii KT|TrEMBL
METPLHLPVADGAAVRILQITDTHLFAGETDTLLGINTLHSYHAVLDAIVKQQLPADLIV
ATGDLVQDQSTRAYQRFTDGIARLPAPCVWLPGNHDYQPSMAQELAAAGISPSKQVLLGD
QWQILLLDSQVQSVPHGELSDDQLIWLDNCLAQQPDRHTVVMLHHHPLASGCTWLDQHSL
RNSHMLAEVLTRYQNIEGILCGHIHQDLDVMWNGIRMLATPSTCVQFKPHCTNFTLDTAA
PGWRYLELTTGDNPSLTTQLFRLDTDEFSPDLGSDGY
>A0A2S6WZF2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces sp. MH60|TrEMBL
MTSRAGAPGLWAISDLHIGYEENRALVERMHPESDDDWLLVAGDVAETVADIRWALGTLA
DRFRRVVWVPGNHELWTPSRDAVALRGVARYEHLVAMCRELGVTTPEDPYPVWEGAGGPA
VVAPLFLLYDYSFLPAGCATKAEGLEYAQGTGVVCSDEYLLHPDPYPSREAWCRARVEET
ERRLAEIPADLPTIPVNHYPLHRHPTDVLWYPEFAMWCGTSLTADWHRRFRVDTMVYGHL
HIPRTTWHEGVRFEEVSVGYPREWRKRPGPPGQLRRILPSTQAPTAPSRQEVTR
>A0A4Q7BDS7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. WCHAc060025|TrEMBL
MNAEKLQLTEFHKDRVIIQITDTHLMDRPEAEFVGINPEENFHAVMDDIKQQYPHIDAIV
HTGDLAQAAFPETYDRYINYMKAFGVDFYHIPGNHDNLRFFPFHTPEPSPAVVSIGQWRI
ILLNSAVSGQTDGRIQNEQLLELKKILAQLQDCFVIIACHHNPFEMRSKWLDQHKLKNAD
ELKAVLEPFQNIKALIHGHVHQESFNEWNGIPFISTPATCVQFKPLSQEFAFDQIAPGYR
CLHLKASGEFETVVHRLKNFKVTINEEISGY
>A0A1X9TXP2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium damselae subsp. damselae|TrEMBL
MLTYSLPPRQSDSVVLLQITDTHLFANDAGSLLGVATKDSFHAVLAAIDHQARPFDAIIA
TGDISQDHSTESYQHFAQGIARWQQPCFWLPGNHDYQPSMKAVLPSPQIKPCEQVLLGEH
WQMILLDSQVPGVPHGELRAEQLEMLDRALAAHSERHALVLLHHHPLAAGSAWLDQHQLH
NADDFWQVLARYPAKVKSVLCGHIHQELDCMRQGVRVLATPSTCIQFLPDSDDFALDSKA
PGWRYLELTPQGDVHTQIHRLANDQFAPDLNSAGY
>A0A8C4LHT9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Equus asinus asinus|TrEMBL
MHVCQMPSAVALMRTLFSAFSLSFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRR
ESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTILTNLHG
TSNKCNLCNFPGVIGRIGCHE
>A0A2K5C6C0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aotus nancymaae|TrEMBL
METLGVGEGAEACSRLSRPRGRHGTARAPKHLWRQPRRPIRIQQRFHSDPEKSAGCREQD
LSPRPGLRKLRLSWPISSCRRFDLENGLSSGRSALDPQSSPGLGRVMQAPVHHSQRRESF
LYRSDSDYDLSPKAMSRNSSVASDLHGEDMIVTPFAQVGFGGGVRWAGQPRLRLLYRRQG
PVGNLSSSHQPPPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNR
ELTHLSETSRSGNQVSEYISQTFLDQQTEVELPTVTTEEPPKPVSQISDLHGLCHSASLS
SATVPRFGVQTEQEEQLVKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTF
QIPADTLATYLLLLEGHYHADVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALF
ASAIHDVDHPGNHHLAVGFKLLQAENCDIFQNLSTKQRLSLRRMVIDMVLATDMSKHMNL
LADLKTMVETKKVTSLGVLLLDNYPDRIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAE
FFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTL
EDNREWYQSKIPRSPSGLTNPERGGPDRFQFGLPLEEAEEEEEEEEEEGEETALDKEALE
LSDTELPPEASPDPGDLPLDNQRT
>A0A506PWM4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea deleyi|TrEMBL
MDSLLTLPAANGSGFRILQITDTHLFAGKHESLLGVNTWSSYKAVLDAIIAQQRDYDLII
ATGDLAQDHSAEAYQHFAEGISRLPRPCVWLPGNHDFQPAMVDTLAAAHINAHKQVLLGE
AWQIVLLDSQVSGVPHGMLSDYQLEWLDNALGCYPQRHTLVLLHHHPLASGCTWLDQHSL
RNSHQLDAVLQRHPLARTLVCGHIHQELDLAWHGRRVLATPSTCVQFKPHCTSFTIDTVA
PGWRWFTLHPDGSLDTEVNRLDTDAFRPDLDSEGY
>A0A1A8FIV6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothobranchius korthausae|TrEMBL
MLLLALWFGLWWRLRQFKRMLNRELTQLSETSRSGNQVSNFIANTFLEKQHDVEILSPPS
KEKEKKKRPMSQISGVKKATQSPSLASACIPRFGVNTPHESQLAKEIEDLSRWGMDIFKL
AEYSGNRPLTVIMYSIFQERDLLKTFKVPIDTFITFMMTLEDHYHMDVAYHNNIHAADVV
QSTHVLLSTPALEAVFTDLEIMAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVL
ENHHLAVGFKLLQEENCDIFQNLSKKQKDSLRKMVIDMVLATDMSKHMNFLADMKTMVET
KKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFTQGDRERD
KGMEISP
>A0A2D0KSS0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus stockiae|TrEMBL
MESLLEIPVAKGATARILQITDMHLFANKGGSLLGINTYRSYHAVLDAILEQNIDIDLVV
ATGDLVQDQTPGAYQNFVEGIARLPAPCVWLPGNHDYQPAMVDVLAAAGISPSKQIFIGQ
HWQLIMLDSQVQGVPHGELTEYQLEWMSKCLDEHSDRQAIVMLHHHPVPSGCTWLDQHSL
RNAPALAECLKGKSQVKTILCGHIHQELDVMWNGIRVIATPSTCVQFKPHCTNFMLDTVA
PGWRYLELPVTGGGEAELQTQLYRLKSNEFCPDLDSDGY
>A0A221UUZ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arenibacter algicola|TrEMBL
MKRYIIISAVFLIFSCSETKKEVEHIHGSVKGVMDSVITRLYEKVDPKDYDSIDDTFMLQ
FLTDDEKSTLASRYQYFKVNVPVTVSLMRHLDHKAPFWLKESGFVKTDEIVKNEVYDYEV
WQKDFDAGWVNLGIPGFDIDRVVYFISVGPQNSNEELTISERYPEEYSLEVFEKGAFTYH
DWSDLKITDLPKELEGQVLFTTVRGRAREAHVEGAFRETIFPSSSRPDQIMLTWSADPTN
SMDVQWRTNTTVKDGTVQYWKKNTSDTISLNASVLGMEDRMLFNDRYINRFTANLNNLEA
GSTYEYRLGSTEEKSWSPVRSFKTEAKDSKEFSFIWFGDTHRDPKWAKILNDADLRHPET
AFYSIAGDIVTTGLYRTEWDMFFGYSKDVFSNKPLIPVPGNHDRQDGLGAWMYYQLFSLP
TNGPEKVDPESTYAFNYGNALFLMIDSTQPNETQTQWIENQLKNSNATWKFVMFHFPPFN
FEEPYLDIQQEWGGLFDTYHVDMVMSGHIHYYMRSKPINNGKVVDSFKDGTVYVVSIGTN
GNHDDIGEEPYAEKRFKDGQFYQYMTLTDKTLKYTTYNQDGEIVDELLIKK
>A0A7U9R9D8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lachnospiraceae bacterium|TrEMBL
MNYIPNNIKASWLHISDLHVFPEADTTLMLDDYKELAKIISPQFLVVTGDFRHKKYKTDF
SLACDYLELLIGIFNIDKQDIFLVPGNHDVNSYDGREDAISDICLHSKKNDYNFYSKYLL
NKGFSE
>A0A7U9MP60|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lachnospiraceae bacterium|TrEMBL
MREWKIGKRGTRMLIEMCGALFAGMAAVIAYDSNRFIRQDYHIHSDKFRKKADILLLSDL
HNKSYGKGNKKLLAEINRIRPDFIVVAGDMMTSDGEKSSYEVPLKLLRHLAEKYPVYYGM
GNHEYRVKVYRKVYEDMFVRYKRELENCGVRFLENEKVYLPEYNIEICGLEIERRYYKRW
RRTAMEKGYVDRLLGKAKKDCYELLIGHNPDYFKEYADWGADLTVSGHVHGGVVKFPFLG
GMISPSMRIFPKYDGGMFEENGKTMVLSRGLGMHTIPVRVFNPGELVVIHCENDVLG
>A0A4P6M0Z6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Blautia producta|TrEMBL
MQIIMILILLGAVIGLIVNTGRKLFLWFRPLFAGASPLVFGAIYGMIMTAVLVFFVLSRI
PDSPIPRVFFLADHYALGAAVYVVIFVNSADFVLFLLKLCRLLPVPLSQGVSVTAGAAAL
GLSAVLTLYGGIHASMIKTQHYDIELQADKRASDSMKIALISDIHMGYVIEEKHVEKIVA
AINAAEPDLVCIAGDIFDGDITALKNPSVLQELFREIKAPYGVYACLGNHDAGAGYEEML
DFLDKAGIHLLQDEEVLIDDRIILAGRKDSGPIGNQGRKRTVLEASAKTEELPRVVLDHK
PENIGEYHKSTDLILCGHTHRGQFFPGNLINEVSMDVNYGYYRKNAESPQAVVTSGAGTW
GPPMRVGTDNEVAVIRITFPTAEKGTVK
>A0A812DIC6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sepia pharaonis|TrEMBL
MSGHRSRSLFRRRHPSGSSDLDTLTVPVITVNMQYLSPNHNTSSSSSSSSSVSQGKTRNW
LSKLRREPRNKSKNSLSSSSRHSEDLIVTPFAQILASLRSVRNNYLNLTNVNLPKERTRR
GSSTGPHGSQREHHQPPPQTSQNSQSGSTNKDEAYYKMALETLEELDWCLDQLETIQTHR
SVSDMASSKFKRMLNRELSHFAESSKSGNQIAEFICSTYLGKSVIFYSFFLSFLILYFN
>A0A1N6ZY72|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella morhuae|TrEMBL
MLKEAVSYSITEGESVRIVQITDPHLFADPEAQLLGVNTYKSLAAVLNTIRAVDYPAHLM
LATGDLSQDYSAESYQQFVKAVTPVDLPCHYLPGNHDDPRIMYLHMQGEQIFGQQRILAG
NWQILMLDSTVRGKPGGNMADSQFELIDKAIAAHPHLHTLLVMHHNPIVVNCTWLDQHCM
DNGAEFLVRVAQYPQVKGLLWGHVHQCIDTYHKGPHGNLQLMATPSTCIQFKPLSPYFAL
DSIQPGYRLLELKADGSINTKVYRVPGNHFSPDNNSSGY
>A0A6P3UIH6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bombus terrestris|TrEMBL
MIDLEINKRRSTQIQIYVCGSTEDANIHGTSTWYSWITRVLCDPFRKKWDTNRDIIHVNE
IPPSLVSPTQKGPQNIEAHPLTNSVPSLIKILLVFPKDDQQMDVLATTSRRLGWSVSVAK
DAEKAVEFFQNRGHELVIIDHRGQRAAEADTICRAIRSSPAYHNSIIIALVKKSFLMHGE
KDKIVTLDLLETGFSRALMECSHERLLINELVGIYASALLPRTQLAAANALYVALDRCRD
MVHVTNDKHIVQFVNKISEKLLGYKTSEILGRSIADIVVYDNFVLMEQHISKGREFEGNM
NCKRKNNQMITISCRVIPFSISLKKPTHYIYIYDTTYLSENIGSLSPTPSQSVYSRGNMI
VSQRRTSDMKSSEGRRRSSAHKLHSLQLDAPITKVISLLSNAITESTTPDTTAQIEKAID
ILKTTELYVPSLREDTDPVTTDLVGALLASPRKAWESRRSSVESTRVSTTKGFTTTTASR
MQIKGFRGPQEIAEILERCLEWNFDIFKLEILTEKRPLLFLGTTIMNLYRVPARLGCEEK
VVQNWLTVIEMNYQSRNSYHNSTHAADVLQATARFMQSERLQQILEPLDEVATLVAAAAH
DVDHPGRSSQFLCNSDNKLAILYNDLSVLESHHAALTFKLSLSDDNVNIFKNLERDTYKQ
LRQTVIDMILATEMTKHFEHLAKFMNVCSARMMDSPQLDDYSDTVDMSVVLQPENVVLVK
RMMIKCADVSNPTRPLKCCVEWARRIAEEYFNQTDEEKRMQLPVLMPMFDRATCSIPKAQ
IGFVDFIINDMVEAWDAFIDMPEMVGYMRQNYEKWKEYNDRGISTLPDIEKIQELPELRI
YQLPS
>A0A5P9QEI6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Luteimicrobium xylanilyticum|TrEMBL
MTDVRPLRILHVSDTHLLGDGGRHYGVVDTTAALRSVLERASTVSDVDVVVLSGDLSDDG
SPASYQALVELVEPWAAERGAVVVPAMGNHDLAAGFEEVLGERERTVLVRGFRVVTVDTS
VPGAGYGRLDPAQLDRLRGALAGLEDPDRATRPEEAADAPLRPTVVVLHHPPVPARSALL
AALELQDPGALLELCEDAGAVGAVLAGHYHHALVATAGRIPVVVAPGVANSSDPLAPCGH
ERAEVGSGFAVVDVHDDGAVSAVFVPVPHASDVADGTELFDLAPDEVERIAALAGPGASS
>A0A399EKM8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Calidithermus roseus|TrEMBL
MISMRFPWLAAHEVNRYAQPLPGLERPVRVAHLSDLHIGYYIDSRIVRRWVETTVAHRPD
LIVISGDLTDTHRAEWIRPAVAELAGLKAPLGTWAVWGNHDYRLRRYKSRDLSDLQGWLE
QAGVRVLNNAGVQVRDDLYLAGVDDLWHGQPDVERALREHEGGAVLLVCHNPDYFFEIPA
KVGLTLVGHTHGGQVKLPIIGPVSTSSRYGKRFAEGWFENPVKGFVSRGLGVSMLPIRFR
ANAEIVIHDLQPDGKR
>A0A4Y6IXA1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella marisflavi|TrEMBL
MLKEAISYSIDHDESVKLVQVTDPHLFADPEAQLLGVNTAHSLDAVLNTIKAVEYPAHLL
LATGDISQDYSNQSYHNFVAAIEKLNLPCHYLPGNHDDPRIMNLHMQGPRVYGDRRILLG
KWQIIMLDSTVRGKPGGHMADSEMAFIEEAVAAHPDKHTLLAMHHNPILVDCKWLDQHCM
DNGEEFLDRVSSLPQVKGLLWGHVHQGLDQVYAGNSGPLRLMATPSTCIQFKPKSPYFAL
DAQQPGYRLLELRPDGSILTNVYRVPGNKFSPDHESSGY
>A0A0N8JYB8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Scleropages formosus|TrEMBL
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLVSGDFDHLGFLHL
FAFLERKKKNR
>A0A836YWW2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Glaesserella parasuis HPS10|TrEMBL
MDDSYIFPLSSPIIRILQITDSHLFASDTCELLGVNTTQSFQAVLNMIMKESFEYDLILA
TGDLVQDHNREAYHRFAKMVKPLVKPLFWVAGNHDLQPQMRNALSIYSQIKPEKHILVGD
HWQIILLDSHIQDSPKGRLEFSELAFLKRKLEVHPERYSLIVLHHNILPTNSAWLDQHSL
SNVNDLLATLKAFPKVKAIVHGHIHQEVDAQWNGYRILSTPSTCIQFKPHCNDFTLDVIP
QGWRELCLNIDGFIDTVVKRLDNNNFLPNFKALGY
>B5REE2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella gallinarum (strain 287/91 / NCTC 13346)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCSNFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A1A7P0K8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gallibacterium salpingitidis|TrEMBL
MSDLFQDESTGVIKLLQVTDPHLFADANGELLGINTYASFQQVLSEIKSSGFESDFILAT
GDFVQDGSEEGYHRFVKEIAQLGKKVFWIPGNHDFQPKMEAVFDVYKAIIQPQKHLLLGE
QWQVILLDSQLYGVPHGMLAEDELTWLEQRLAMYPDRNTLVVLHHHLLPTRSAWLDQHNL
RNPYDFSEVLAKHKKIKGIFYGHIHQEVNGEWQGIPVFSTPSTCIQFKPDCAHFTLDNLQ
PGWREITLYPDGHLETRVQRIKEKVFLPKDNMNGY
>A0A833Q7R1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Burkholderia gladioli|TrEMBL
MSRLLQISDPHFGAERQEAVDALVRLVEQTRPELVVISGDLTQRARRHQFEAARAFVARL
GAQPVLAIPGNHDLPLFDLIARWRQPYANYRRAFGEELEPVFDAPALLAIGVNTTRPARH
TAGEISAEQVARVARRLALASPAQLRVVVVHQPIVAIGSANRHDRLHGGEIALRRWAAAG
ADLVLGGHTHRAGAWRVTPRDDEAGRDGAVEQPVFMVQGGTAVSRRLRAGTPNSVNLIDY
VGDALGPRRAAVTRCDYDDESRCFIAQAAQHLDLAPATPFLLA
>A0A8B9QES8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Apteryx owenii|TrEMBL
ADGGGAAVPTGGAPGSPCTRLPSGFDLENGPSGRGSLDPQASPGSGLVLQGTFAHGQRRE
SFLYRSDSDYDLSPKAMSRNSSIASDLHGEDMIVTPFAQVILASLRTIRSNFAVLTHLQD
RAGTK
>A0A2D4H1H1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micrurus corallinus|TrEMBL
RISNSTMESLPSLKPNYMSVCLFAEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMAS
NKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVE
>A0A233HFJ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. V15_P4S5T153|TrEMBL
MNVSPTLDNSDSIKLLQITDTHLFAPDDGSLLSVNTVDSFHAVVAEICAQRVEFDAILAT
GDISQDHSAESYLRFSRGISSLEKTCFWLPGNHDFKPNMGAVFPSEQIQQSEHVLLGEHW
QMVMLDSQVVGVPHGRLSDQQLALLDEKLSTHHQRHTLIVLHHHPLLVGSAWLDQHSLKD
SDAFWNIVTQHRNVKAVLCGHVHQNMDKLHHGVRVMATPSTCVQFKPNSDDFALDRTSPG
WRELTLSADGQIETQVKRLANGAFQPDFNANGY
>A0A6C0XH32|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter schindleri|TrEMBL
MTQTSTPASEKVWTLIQISDTHLMDQPELEFARMNPEQSFLEVVHDIQQRFPHIDAVVHT
GDLAQVAAESTYQRYLQFMRAWNVPHYQIPGNHDDYLAIFPFYKNSDEAHAISFGCWTLI
LLNSAVKGRVDGWVEQKQLDQLEQLLLEHSKQYVIVACHHHPFAMQSHWIDQHRLKNSEA
LKDVIARHTNVKMVLFGHVHQDSENEWQGVRYLSTPSTSVQFKPLSENFALDQAQPGYRV
LQLKDNGEYQTYIQRVVLKQAKINTEISGY
>A0A8F0CJL1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Inverness|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5C8Z2E1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Reinekea thalattae|TrEMBL
MAVMMEQSYTLLQITDPHLHASKEGTLLGMNTYDSLQQVIGQVQLCGSNIDLLLATGDIS
QDGSQQAYQHFLNSVSAIDAPMYWIPGNHDCPRGMSHSSKGFNHEQSVLELGSWLIVLLD
THVCDEVHGELSHTELDRLERALEQHPNHHVLISCHHHPINIGSAWMDKIGIHNGDKLQA
IIRCHNNVRCVLFGHVHQQSDRTLNGVRYLSTPSTCVQFLPNSDEFATDSQPPGFRVLKL
KANGQIETRVSRVSHFKVELDETLTAY
>A0A2S4QE47|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter freundii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRIFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A2X2RL23|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter freundii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQIQVRRLQGNRFHPDTASEGY
>A0A147BEB9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ixodes ricinus|TrEMBL
TANATTMTAPGSLTTTAAPKGGCGAGVLRGNAHRFENNFPKVRQKVVNCDGVNDCAVPLC
SIPEDGRKGTVALKFGSMYLTVPSVRVLFVFVKEDAQYNALKWASEKMHYEYRLACSMDE
AVESYLNVQPHLVFIDARSKTCVDPIALCRTLRGFRGSQFSCIVAVVKKGLAEKEEAAII
PLLKSGFNRWFTETCSFGVCLNEMIQIEHNDLINLWKLRASEALFSALHIARDGVIITGS
GHEIQFMNRAAEKLVGYSVEEMLGVNAQELHRTDSLKTDVVQTISTQLKKGKEWEGTLFH
KRKSGECIPMWSKIAPVEIHTGISDHLVYIKECPFFMEKPFSPDADCLPYQLNTSLKSSR
KASCDVRSLCSEVGMNRRQSFAKFHAMTIEAPITKVINMLVATQENSPVFVVQALDRVLE
ILRSTELYNPQLGVGQGKSEDQMTSDLVSGLITTGQKPTGVRRLSHETGVVKVNVTTPST
TLPSLSTAPSKIKDLLENDVKWEFDIIELETLSGRRPLIWLGLSLFSKLNVHTSLDCDDA
TIRNWLQLVESHYLENPYHNSTHAGDVMQATAYFLLKLRKKDIFDPLDEAICLISAVVHD
IDHPGKSSPFLCNSDNELAILYNDRSVLESHHAAFAFKLTLSDEKVNIFQNLEREVYRTV
RLSVIDMVLATEMTKHFEHLSKFLNAFQKPIQEDEAFESEAMPDHGDSGLRSAENIILIK
RMLIKCSDVSNPARPIQLCSQWASRIAEEYCAQTDEEKRRGLPVVMPAFDRATCSIANSQ
TGFINYFVRDMFRAWSDFGEFPELMEYIEKNYIYWKDKEPQSNK
>A0A654D7F9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacterales bacterium 8AC|TrEMBL
MESLFQLPVASGATVRILQITDTHLFAGKSETLLGINTYSSYHAVLDAIIAQQRASDLIV
ATGDLAQDHSLAAYRHFAEGITRLPAPCAWLPGNHDFQPAMVDALAAAGIAPSKHILLGD
RWQVLLLDSQVFGVPHGELSDYQLEWMERCLIAFPERYTLLLLHHHPLASGCTWLDQHSL
RNSHMLDAVLAHYPKVNTLLCGHIHQELDLDWQGRRVLASPSTCVQFKPHCTNFTIDEVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A6J8DKC3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mytilus coruscus|TrEMBL
MLEMTDARMDVSENEGVELDDVFSMDSDRSKSVIEQLVKEKFQTPDKFLFKRSSSWMNRP
KSVKRHEKIKAASFDVENGTGPGRPNLEGSSPSSSRLVLQNLPQRRESFLYRSDSDYDLS
PKSVSRHSSMQSEMSPPTPTSNSNKVPQVKPCDTCFNLIIIECFKAPLNLKRYAF
>E7A7C8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae F3031|TrEMBL
MKNAFVYQTEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLKPPMNVAKHLLLGEHW
QALLLDSQVYGVPHGQLSQHQLDLLKETLGKNPERYTLVVLHHHLLPTNSAWLDQHNLRN
SHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQPG
WREIELHSDGSIRTQVKRIQQAEFLPNMQEDGY
>E3PJF3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O78:H11 (strain H10407 / ETEC)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPGRHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A4V2X7G5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus luminescens subsp. mexicana|TrEMBL
MESQFELPVVEGTTAKILQITDTHLFANKEDTLLGINTYRSYQAVLDAILKQNADIDLIV
ATGDLAQDQSLEAYRHFADGIARLPVPCVWLPGNHDYQPAMVDALAAAGVSPSKQILIGK
HWQLLMLDSQVQGVPHGELSEYQLEWMKKCLDSYPERYTAILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQGYSRVKAMLCGHIHQEMDLDWNGIRMMATPSTCVQFKPHCTNFTLDTVA
PGWRYLELSVADNGEFSLATQVHRLESNEFCPDLDSDGY
>A0A8D9RFF5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mannheimia haemolytica PHL213|TrEMBL
MDAKRMHEYIKLPVTGVIKLLQITDPHLFSNPEETLLNVKTVKSFSAVIEQINKQAKQYF
DLVLATGDLIQDNNIAGYHYFAQITNSLNSPIVWLEGNHDVQPSMSEILAQYKHILPHKQ
ILLGEQWQLLMLNTQVVGMPYGELSYSQLKWLEEKLAQYPQRFTLVALHHNILPTNSAWL
DQHSLKNSNELSEIFAKFKNVKAIVHGHIHQQVDDIWHGIPIYATPSTCIQFKPNCDQFT
LDLQPQGWREIELHENGTIETVVKRLNSNDFLPNVNAIGY
>A0A1H7UGR6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurella skyensis|TrEMBL
MDYFYHPLNTNESIRLLQITDTHLFAKRNEQLLGVNTYHSFHAVLDAVLDSEFPFELVLA
TGDLVQDHNEQGYHDFAEIVSPLKKPVFWLQGNHDQPEMEKVLNKYPQISPMKHILIGKK
WQILLLDSQVYGVPHGNLDAYQLQWLEQKLTQYNEYYTLIALHHNILPTHSTWLDQHSLR
NAHELSEVLKPYKKVKAIIHGHIHQEMDRMWNGIRILATPSTCIQFKPNNHHFTLDLVPQ
GWRELILHPDGSIDTVVKRLATNEFLPDFNAEGY
>A0A7S6VU15|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter piscicola|TrEMBL
MSTYQINSKNREPVIIQISDTHLMTDPNEHFIGISPEQNFHAVIAQILQEHPHIDAIVHT
GDLAQQATTETYQRYQAYMQSLGIPFFQIPGNHDDLSLFPFLMPLPEPACVEIGDWCFIL
LNSAVPKQVDGWIQTEQLLHLTHLLQQTQDKFVILACHHHPFEMHSQWIDQHKLKNTDQL
TTLLSQFTHIKAVLFGHVHQESIHVWNNIQFLSTPATCAQFKPLSENFALDEAAPGYRYL
HLKSDGQFESAIFRLKDYNQTINNEISGY
>A0A7Y8JTX0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. P7548|TrEMBL
MPSVSTVSPDASALLVQLSDSHLFAEADGTLLGMNTRESLQRVIDLVCAQQPQIDLILAT
GDLSQDGTLASYQQFREMTRAIDAPARWIPGNHDEPQIMAHAAIHSDLLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPNRHHLVCFHHHPVPIGSAWMEPIGLRNPD
ALFTVLDRFPQVKAVLWGHVHQEIDRQRNGVRLLASPSTCIQFAPGSEDFNVSEQAPGYR
WLRLHPDGRLETGIERVQGFAFTVDYGSNGY
>A0A2G4U6K7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia bercovieri|TrEMBL
MESLFKLPMASGAKVRILQITDTHLFAGEHETLLGVNTSHSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGIARLPAPCLWLPGNHDFQPAMVDALADAGIAPSKQVLVGD
NWQILLLDSQVFGVPYGELSDYQLEWMERCLEAYPARYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAATLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPNGVLETEVRRLASDEFCPDMDADGY
>E9PNB0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|TrEMBL
METLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTF
LDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLA
KELEDLNKWGLNIFNVAGYSHNR
>E9PMG3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|TrEMBL
MSFDVENGPSPGRSPLDPQASSSAGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRN
SSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQE
ESYQKLAMETLEELDWCLDQLETIQTY
>A0A7Y2PHK8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. GC01|TrEMBL
MPSVSTLTTEDPVLLVQLTDSHLFADAEGSLLGLRTADSLQQVIDLVRGEQPQVDLLLGT
GDLAQDGSIAAYQRFRQLTGSLCAKARWIPGNHDNLPHMREAAVQSRLLDPVVDLGNWRI
TLLHSNVEQKSQGYLQDSQLQLLAQSLSEAPDRHHLICLHHHPVPVGCEWIEPIGLCNAG
EFWKVIDRYPQVRGVLWGHVHQAFDQQRNGVRLLASPSTCIQFAPGSADFKVSSEAPGYR
WLRLQPDGTLQTGVSRVTDFVFEPDYSANNY
>A0A4V1AVZ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nitrosococcus wardiae|TrEMBL
MVAPGDWEVTNNPSQFVRVMQLTDSHLLADPGALLWDNLNTRRSMVAVFKHIQQQRHPGD
LVVISGDIAEKAEPEAYRWLLEYCQDLELPVYCLPGNHDNPALMGEILNDANVSTEPLIT
FESWQLILLNSIVPRQPNGHLGKGQLDFLNRSLASRPDLNTLVFLHHPPVAIGSSWMDAM
GLDNAVDFFAVLDQYPQVRGIVWGHIHQEFHTERHGVQLLGSPSTCVQFVPGSEHFQLDQ
LGPGYRRLVLFPNGQIETQAYYVEHFGFS
>A0A1X1MLK3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. qd031|TrEMBL
MSQHVAPSKDRVELVQITDTHLFEPADGNLLSVNTEQSFHAVVQNVIDSQCAFDAVLATG
DISQDHTPASYQKFVQGIRPLVKQCYWLPGNHDYKPSMGSVIPTGQIVEDTHVMMGKHWQ
LILLDSQVVGVPYGELSQQQLAMLDQCLNQHPDKHSLVLLHHHPVLIGSAWLDQHTLRNA
SQLWEVINRHSNVKGLVCGHVHQDFDQLHSGVRVIATPSTCAQFKPNSNDFALDNVAPGW
RSLSLLENGQIETQVYRLASGLFEPDFDAEGY
>A0A5M7Q726|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. M_5|TrEMBL
MDSLLTLPVANGSEIRILQITDTHLFAGKHESLLGVNTWSSYEAVVEAITAQQRDYDLII
ATGDLAQDHSVEAYQHFAEGISRLPRPCVWLPGNHDFQPAMVDTLAAAHINAHKQVLLGE
QWQIVLLDSQVPGVPHGMLSDYQLEWLDNALARFPQRHTLVLLHHHPLASGCTWLDQHSL
RNSHQLDAVLQRYPLARTLVCGHIHQELDLLWHGRRVLATPSTCVQFKPHCTSFAIDTVA
PGWRWFTLHPDGGVETEVNRLDTDAFRPDLDSEGY
>A0A4Z2DYU1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Liparis tanakae|TrEMBL
MLNRELTQLSETSRSGNQVSEFIANTFLGERWLRPLCLRANTTTSLHSHELIPLVLMDQL
VYTLDNSLDVYGVKYNK
>A0A1B8HTA2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Morganella psychrotolerans|TrEMBL
MEIPLHLTVADGAAVRILQITDTHLFAGETETLLGINTLHSYHAVLGAIVKQQLPADLIV
ATGDLVQDQSIRAYQRFTQGIACLPAPCVWLPGNHDYQPSMAKELADAGINPAKHILLGE
QWQILLLDSQVQGVPHGELSEYQLAWLDECLAQYRDRHTVVMLHHHPLASGCTWLDQHSL
RNSHELADVLVKYQNIDAILCGHIHQDLDMMWNGIRVLATPSTCVQFKPHCTTFTLDTVA
PGWRYLELTTGELPALKTTVHRLDTDEFSPDLGSEGY
>A0A509B1S4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella sp. NCTC 3046|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A0V9JBP2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. 50677481|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLKAIHAEGQEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVMIGE
HWQILLLDSQVFGVPHGELSEFQLEWLEQKLAEAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSVLVNFPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIG
PGWRTLELFADGSLHTDVCRLEGTEFRPDTASEGY
>A0A2H5WS16|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR15|TrEMBL
MITRSPRKRVLRIAHLTDIHVQPEKDAARGMIRCLQAVHRLKPRPDLIFNGGDAVMDVFS
QGRERARVLQQLWRSILRDYCEIPVIHCIGNHDVWGWDREHSGCSGEEPDYGKRWAMELF
ELEQRFYSFDRMGWHFIVLDSTFPHGNGYKARLDDEQFEWLQADLKRTPASMPVCVLSHI
PILSASAYLDGNNEKTGDWVVPGAWMHIDARRLIELFWKHRNVKLCLSGHIHLYDRVDYN
GVTYLCNGAVCGAWWNGDYHQTPPGFGLIDLHSDGTFESQYMLYLSGSAQPLWKG
>A0A3G2FIK3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia sp. 3ACOL1|TrEMBL
MESLFRLPVASGAKVRILQITDTHLFAGKHETLLGINTYASYHAVLDAVIAQQRECDLIV
ATGDLAQDHSQAAYRHFADGITRLPAPCVWLPGNHDFQPAMVDALAAAGISPSKQVLLGD
NWQVLLLDSQVFGVPHGELSEYQLEWMERCLEAYPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHTLAAMLWRYPKVNTLLCGHIHQELDLGWHGRRLLATPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A0S7GXR3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
KVTLQNSPFASFTRLSCPVQRHWDSSEPASSVELLQDPDVRYAVKRVFSGNVQLPRLSCR
PSAQERAQDGAPPEPAAPPTRSIRHSRSLGTLTSCFDVENGLSVPRNPLDAQSSSSSGLV
LQVNYPHSQRRESFLYRSDSDFDLSPKGPSRNLSSTSDLHSEDMIVTPFAQVLASLRTVR
SNFALITGQQDRAASKTRSSGSNPPSMCKTSLAGLCRCQRGFADQYPIVNIELNDLELEA
PSLWS
>A0A330F6L4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. SM1B|TrEMBL
MTQTSTPASEKVWTLIQISDTHLMDQPELEFARMNPEQSFLEVVHDIQQRFPHIDALVHT
GDLAQVAAESTYQRYLQFMQAWNVPHYQIPGNHDDYLAIFPFYKNSDEAHAISFGCWTLI
LLNSAVKGRVDGWVEQKQLDQLEQLLLEHSKQYVIVTCHHHPFAMQSHWIDQHRLKNSEA
LKDVIARHTNVKMVLFGHVHQDSENEWQGVRYLSTPSTSVQFKPLSENFALDQAQPGYRV
LQLKDNGEYQTYIQRVVLKQAKINTEISGY
>A0A6G9Q2D9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lentilactobacillus hilgardii|TrEMBL
MVQCKIVQISDTHLTPAGAKPANHQHLDPEEKLRTVFDDIYNTNVDPDLIVISGDLIHEG
DAEVYADFHHMLDQEQERLMAPIKVILGNHDRTDQFYKGFLGKKRVATRCYYHESLEGLE
CYFLDTKCGDIEQGYLDQTQLHWLKNQLQEYQRPGIIFMHHPLYGPPLQQMRYSILQNGD
DLLNVIDHTHVKAIFSGHVHFANSYVVDGILNVVADSTAYHINCANPHEHFVTDGTAYNV
ITVDGDDIGVEQRLLYLGTKTINAFKIPNTDFVDKKILTRAWSNVLSKE
>A0A0T9V4P1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia frederiksenii|TrEMBL
MESLFKLPMASGAKVRILQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGIARLPAPCLWLPGNHDFQPAMVDALADAGIAPSKQVLVGD
NWQILLLDSQVFGVPYGELSDYQLEWMERCLVAHPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTIDTVA
PGWRYLDLLPNGILETEVRRLASDEFSPDMDADGY
>A0A0T9UAS4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia frederiksenii|TrEMBL
MESLFKLPMASGAKARILQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQRPFDLIV
ATGDLAQDHSVAAYQNFAKGISRLPAPCVWLPGNHDFQPAMVDALADASIAPSKHVLVGE
HWQILLLDSQVFGVPYGELSDYQLEWMERCLVAHPERYTLVLLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGILETEVRRLASDEFCPDMDSDGY
>A0A7I6H8R0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O9:H4 (strain HS)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A8B9NMH1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Accipiter nisus|TrEMBL
AAESFSTPASAAARRPGGFKEERSPYAFPCLFAEGAYQKLASETLEELDWCLDQLETLKT
RHSVSEMASNKVGARGRRLPSAAPFQEFSHVPFISMLSFMILAYKQYVVKFLELMLKAKL
ISLLPCFRIYFYICHQQLF
>A0A241PSX0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio anguillarum|TrEMBL
MNVSPTLDNSDSIKLLQITDTHLFAPDDGSLLSVNTVDSFHAVVAEICAQRVEFDAILAT
GDISQDHSAESYLRFSRGISSLEKTCFWLPGNHDFKPNMGAVFPSEQIQQSEHVLLGEHW
QMVMLDSQVVGVPHGRLSDQQLALLDEKLSTHHQRHILIVLHHHPLLVGSAWLDQHSLKD
SDAFWNIVTQHRNVKAVLCGHVHQNMDKLHHGVRVMATPSTCVQFKPNSDDFALDRTSPG
WRELTLSADGQIETQVKRLANGAFQPDFNANGY
>A0A4V2J8J9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hafnia alvei|TrEMBL
MESLFQLTVARGAPVRILQITDTHLFAGEHETLLGVNTYRSYHAVLEAIHAQSRPYDIVV
ATGDLAQDHSVAAYQHFAKGIATLNKTCLWLPGNHDFQPAMVDTLADAGVSPAKHMLLGD
HWQIILLDSQVFGVPHGELSEYQLEWLDRTLSLYPARHSLILLHHHPLPSGCTWLDQHSL
RNAHMLGEILQHHPLAKTLLCGHIHQDLDLEWQGRRLLATPSTCIQFKPLCTNFTIDTLS
PGWRYLDLHPDGTLTTELHRLEGTEFRPDLDSDGY
>A0A2R8CDU3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Falsiruegeria mediterranea M17|TrEMBL
MTTILQISDTHIVAPGGLVAGRLDTADALDRLVARIGAIRHQIGVLDAVLVSGDLSDDGS
AQSYDHFKTLITPLEVPLHVIPGNHDARAPMRAAFADQIPGAGPINWDHRTGEICLIGLD
TLVEGQKHGTLTVETLTFLRDALVRADGAPVLLALHHPPFSCGIRFMDDIGLTNQQDFAD
AVGGYAGELRIVCGHIHAMMIHTVAGQVAVSAPSPNSTFAYDRRPDAPVGFHTQEDGCLL
HRWDGGFQSIRIGPNDGAGPFPFKID
>A0A7T1SUY6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter hormaechei|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEKRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGD
QWQILLLDSQVFGVPHGELSDYQLDWLETKLAAEPNRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDGVLAKFPLVQNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLAGAQFRPDTASEGY
>L0M064|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacteriaceae bacterium (strain FGI 57)|TrEMBL
MESLLNLPLAGGASVRLLQITDTHLFAKKSETLLGVNTWDSYHAVLEAINASQREVDLVV
ATGDLAQDHTSAAYQHFAEGIARFSAPCVWLPGNHDFQPAMYSTLQDAGISPAKRVMVGE
HWQILLLDSQVFGVPHGELSEFQLEWLEKRLAEAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAASLDNVLVNFPKVKNLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHADGSLTTEVCRLAGSEFHPDTASEGY
>A0A828AEL8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEVLLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYLHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCRWLDQHSL
RNAGELDNVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>F9RL83|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio scophthalmi LMG 19158|TrEMBL
MKVTSSSSAKDTIKLVQITDTHLFAAEDGSLLSVNTNDSFSAVVEAVTQQDFDFDAILAT
GDISQDHSDVSYQRFAQGIEPLKQPCFWLPGNHDYKPSMGSVLPSTQIVQAEHALLGEHW
QMILLDSQVEGVPHGRLSQQQLDLLDEQLRLHPERHSLVLLHHHPILVGSAWLDQHTLKD
AEQFWQVVEKHDNVRAILCGHVHQDMQKVRSGATVISTPSTCVQFKPNSDDFALDTCSPG
WRELTLYADGQFETHVQRLAGGLFLPNFDSSGY
>A0A509E9Z6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium symbioticum|TrEMBL
MTATPFRLAHLSDPHVGPLSRPRLRQLLGKRATGYANWRRGRSRSHDMEVLAALVADLRA
QAPDHIACTGDLCNIGLPSEWETARVFLEALGAPGAVSFVPGNHDAYVRGSLEGLLAACD
GWTADDGGLGGCFPYLRRRGPLALVGLSTAIPTKPFVASGRLGPAQIAAAEALLRALATE
PGRPCRVVLIHHPPHPGGALPGRDLTDAKALAAMIARTGAELILHGHNHVTSLAALPGPN
GAPVPVVGASSASARPGAHGPSPARRAAYLLFSFVREGERHVITARQRGLDPDGTVADLG
ALALV
>A0A509EBK3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium symbioticum|TrEMBL
MRIWILSDLHQGVGGPPWNPARIPEADVVVVAGDVCEGLGAAVDWAAEALGRHMPVVMVA
GNHEFYRRIHGEELALGRAAAQAAGIHLLEDEAVALGGVRFCGATLWTDYALDGLERRRA
AMDAAGRGLNDHRRIRWGHARRPFRPEEALGLHEASRAFLDAVLRETPGGLPQVVVTHHG
PAPASVAPVFAGDPLNPAFVSDLGPMIEDRRPALWVHGHVHASLDYVHAATRVICNPRGY
GSENPAFRADLVVEVGA
>A0A6I6Y500|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MPHPDPSPAPVHVVQLTDAHLFANPAGTLLGLNTRDSLRHVVAQVRREQPRVDLLLCTGD
LSQDGSVASYEAFRELTGGFAVPTRWLPGNHDEAKIMAEVAPELVQSVTDIGSWRVVMLN
TAVPGATHGLLEQDQLSILAEALATAGERHCLVCCHHQPVDIGCAWIAPIGLRNADELLQ
RLRGYPQVKALLWGHIHQAWDERRDGLRLLATPSTCIQFAAGSEDFKVSEEQPGYRWLRL
HADGRVETGVERATDFEVKLDFNSAGY
>A0A8I0Z3L8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MHPDQTRPVHVLQLTDAHLFADPAGSMLGLNTRDSLRHVVAQVRREQPLIDLLLCTGDLS
QDASVASYEAFRELTAPLAVPTRWLPGNHDEARIMAEVAPELVQAVTDVGAWRIVMLNTA
VQGATHGLLESDQLAVLEAALNEAGERHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDIV
EAYPQVRALLWGHVHQEWDEVRDGRRLLATPSTCIQFAARSEDFKVSEEQPGYRWLRLHA
DGRLETGVERATDFAVKLDFDSPGY
>A0A807Z8G1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas salmonicida subsp. masoucida|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQVNEHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VMLLDTQVRGKPHGVLGDHQLAALDSALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRVASQVWRLPVGQFVPDPDATGY
>A0A715S5N0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Typhi str. CT18|TrEMBL
DLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGEQWQ
ILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSLRNA
GELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIAPGW
RTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A539CUP1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Beijerinckiaceae bacterium|TrEMBL
MKFLLAHLSDTHLGPLPRPRRRELLGKRVTGYLNWTRSRSRVHDMGVLAQIVADMKAHHP
SHVAVTGDITNIGLPAEFQLAREWLETLGPPEDVSFVPGNHDAYVRGSLPDLARIFTPWT
TGETRGGEPFPYLRVRGDVALIGLSSGVPTPLFIASGYLGRSQLHAAGKLLVEAARRGLV
RVVMLHHPPETSAAHLGRGLVDVRGFASVIHRAGAELIVHGHSHKLCLTRMEGPRGLVPV
VGVPSASVLRGEPHHRAGYHLFEIFGDGSEYKIAARARGLLPGTAVVGDLGPLAL
>A0A8F7MA34|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sanarellii|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVPTAQSLAAVLEQVQANDHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALCQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRVASQVWRLPMGQFVPDPDATGY
>A0A4Y8VU51|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas kribbensis|TrEMBL
MPSVSTLTTADAALLVQLSDSHLFAEADGALLGMKTRESLQKVIELVLEQQPQIDLMIAT
GDLSQDGTLESYQQFRQLTAQIDAPARWIPGNHDEPQIMQMAAVQSALLEPVVDVGNWRV
TLLDSAVPGSVPGYLQDDQLQLLARALSEAPERHHLVCFHHHPVSIDCAWMEPIGLRNPE
AFFDVLDRFPQARAVLWGHVHQEIDRERNGVRLIASPSTCIQFEPRSVDFKVGEQAPGYR
WLRLLPDGRIETGVERVTDFRFTVDYGSNGY
>A0A2N7G7S7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. 10N.261.55.A7|TrEMBL
MKLSSSAAASEAIKLLQITDTHLFAPEDGSLLSVQTLASFQAVVEMVERSAVNFEAILAT
GDISQDHSVESYQHFAAGIAPLKKPCYWLPGNHDYQPNMGSVFPSAQIEHLEHVLIGEYW
QIIMLDSQVVGMPHGRLSDRQLALLDGKLAENPNRHTLVLLHHHPVLVGSAWLDQHTLKD
SEQLWQVIDKHNNVKAILCGHVHQDMDREVNGVRVISTPSTCIQFKPNSDDFALDKCSPG
WRELDLHPDGQLVTKVQRLPNDSFLPDFTAGGY
>A0A8H9K700|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio vulnificus|TrEMBL
MQHTSSDTLSENSIKLLQITDTHLFASDEGSLLSVKTLQSFQAVVEQVMARHVEFDYILA
TGDISQDHSAASYQRFADGIAPLEKACFWLPGNHDYKPNMSSVLPSPQITTPEQVALNPH
WQLILLDSQVVGVPHGRLSDQQLSMLEHYLQASPEKNTLILLHHHPLLVGSAWLDQHTLK
DAEAFWQIVERFPMVKGIVCGHVHQDMNVMHKGIRVMATPSTCVQFKPQSDDFALDTVSP
GWRELTLHANGEITTQVQRLASGCFLPDFSSSGY
>A0A7K0C3B5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinomadura macrotermitis|TrEMBL
MSLRPFRTTGLILLSAAALALPATVAASAQNAGPAARLAAETLLSRGKPVTTSSTETAEF
AGANAVDGSTTTRWASQEGHDPEWITIDLGAPAALTRVKLNWEDAYASSYRIDRSTDGTT
WTSAYSTSSGDGGVDDRAVTGTARYVRVYGRARGTSYGYSLWEVEVYGTPSGPDTQAPSV
PAGLRVTGTTTTSVSLGWSPSTDDTGVTGYDVLRDGAVVASPAGTSYTDTGLTTGQTYSY
TVRARDAAGNVSAASAAVPGVPKAGETTFVATAAGDISEHCKASSSSCGAQQTAKRIEAI
NPDEILTLGDNQYDTGSLADYKAYYDTTWGRFKAKTRPVPGNHEYNDATETAADYKSYFG
ARATPQGKTYYSWERGGWHMIALDSELSMSATSAQIKWLEADLAANTKKCVAAYWHKPLY
SSGPQADAVSKPAWQVLYKYHADLVLNGHDHLYERFAPQNASGGAAADGPRELLVGTGGA
STYDFESTQPNSQKRITDIFGVLKLTLADGSYTADMVHQDGRTLDTTGPTACH
>A0A7R6WA55|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methyloprofundus sp|TrEMBL
MPNTSPALRLIQLTDLHLFADVKQQFKGCATHAALECCLDFIVNEDLRPDAFLLTGDLAH
DHQAATYQRLADMLERFQVPSFALAGNHDDWSVMQSVYPNKGISIDPWQNIGGWRILLLH
TAIPEQADGRIDPKLWAQLTAEMQQQPDKPYLLAMHHNLPAHPLRDIRSSVANAAQYSQA
LANWPAIRAVLSGHVHQPFTIYAGHCLFLSAPSTGVIPYPERVQDSMSRPGFRLIDCFAD
GRIISDIIHPVKR
>A0A7Y1ARN2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. WS 5078|TrEMBL
MPSVSTLTTEDPVLLVQLSDSHLFADANGSLLGLNTARSLQQVIDLVGAEQPSVDVLLAT
GDLAQDGSVQAYQYFRQVTASLAPVARWIPGNHDDVQQMREAAIQSRLMDPRVDVGNWRI
TMLHSNVLKKSHGYLEDDQLQLLAQSLSEAPQRHHLIGLHHHPVPVGCQWIEPIGLLNAE
AFWAVIDRFPQVKAVLWGHVHQPFDQRRKAVRLLATPSTCFQFAANSMDFKVSSEAPGYR
WIRLNPDGTLHTGISRVADFDFEPDYSTDKY
>A0A3Q8D6P3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. CFNIH10|TrEMBL
MESLLNLSLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEGQEYDLIV
ATGDLAQDQTSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKCVMVGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLAAAPERHTLLLLHHHPMPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDSIG
PGWRTLELFADGTLKTDVCRLQGTEFRPDTASEGY
>A0A0T9PLZ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia kristensenii|TrEMBL
MESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAEGISRLPAPCVWLPGNHDFQPAMVDALANADIAPSKQVLVGD
NWQILLLDSQVFGVPYGELSDYQLEWMERCLIAYPERYTLILLHHHPIPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGKLETEVRRLASDEFCPDMDSDGY
>A0A2R8AXZ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudoprimorskyibacter insulae|TrEMBL
MAVLAILAIGLAALLLALLVYAFWIEPAMRLRVVRHQVRHPGWGDRAPLRIVIISDLHAG
APHIPLRRVSRIVRRANALNPDVAVLLGDYSAAHRFTTGGTDKFQIIERLKAFTAPLGCY
AVLGNHDWWQDEKSLKNKTLPEAAKALDQHGIPLLENANVRLRDGADAFVLAGLADQRPQ
SLDPEVPGFDDLDAALNGVASDTPVVLLAHEPDIFPKVPDNVLVTLSGHTHGGQIRTFGF
HPVIMVAETETYSWGRYDRDAGQVLIVSGGIGCSDYPVRFGMVPEITVVELS
>A0A3B4F273|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pundamilia nyererei|TrEMBL
TPRSFKRMLNRELSQLSETSRSGNQVAIHDVDHPGVSNQFLINTNSELALMYNDLSVLEN
HHLAVGFKLLQEDNCDIFQNLNKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKK
VTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDREREKG
MEISPMCDKHNASVEKNQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIP
HSPSPHPEGQEEEEEEEEDEEEGHSSSRRHEIYRSDSASPASRRLPKMLTSDSGRTFSLD
SEKDMAEERETDEGVSGVPRFRIGT
>G5NI84|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Inverness str. R8-3668|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A3Q1GDC4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acanthochromis polyacanthus|TrEMBL
MDRTYAVDTGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSSGRSPLDPMASPGSGLILQAN
FVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFG
ALTNLQQDRASNKRSPMCNPPPITKTTFTGMYVGSGWKSDMITCVCE
>A0A140NQ28|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia stuartii (strain MRSN 2154)|TrEMBL
MDSQLEVTARNAKVVRILQVTDTHLFADTANTLLGINTHKSYHAVLDAILEQNLPIDLIV
ATGDLVQDQSPEAYQHFAKGIERLPAPCVWLPGNHDYQPAMVSSLKLAGISSAKEILIGD
EWQILMLDSQLQDVPHGELSEQQLEWMKSCLDKRPQRTTLVMLHHHPLPSGCTWLDQHSL
RNSHILADYLKGYPQVKVMLCGHIHQEMDEYWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELSINEKGERHISTQVCRLNTKEFSPDFDSDGY
>A0A8C6J8N4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Melopsittacus undulatus|TrEMBL
MGSGPGSPIPLQPRPLSPCSFDLDHGPPGRAVLDPQASSGAGLVLQGTFSHGQRRESFLY
RSDSDYDLSPKAMSRNSSIASDLHGEDMIVTPFAQVLASLRTVRSNLTHLQDRTGIK
>A0A5J4F5V9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcystis aeruginosa NIES-4325|TrEMBL
MRPFWLESLQVERLTIAIAGLPAGLQGIKLVQWSDLHCDEQHLPVAVLQEAIAITNQEKP
DLIFLTGDFITHSPRPIFALVESIKALKSQGGIYACLGNHDSYLPNARETVSSALTSVGI
RVLWNEIVTPYGENFPIVGLADYWSGEFLPQILEQIAPDIPRLVISHNPDTAMVLRDWRV
DLQLSGHTHGGQVTIPGIGSLPIILEELRRSLPEPYGQWVPLHRQFSRVVRYWQWSEGFH
RVGENQLYVNRGLGTYFPGRLFCPPEVTVITLINRSQS
>J2VM14|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. YR343|TrEMBL
MDSLLTLPARDGSDIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIEAQQQHYDLII
ATGDLAQDHTVEAYQHFVAGINRLPKPCVWLPGNHDFQPAMVDTLADAGIKSDKHVLLGD
HWQLVLLDSQVFGVPHGMLSEYQLEWLHTALSKYPERHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLQHFPRARNLVCGHIHQELDLDWHGRRVMASPSTCVQFKPHCTNFTIDTLS
PGWRWFTLQPDGVLQTEVNRLQSDMFRPDLDSEGY
>A0A857F559|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia canariae|TrEMBL
MESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYENFAEGISRLSAPCVWLPGNHDFQPAMVDALADADIAPSKHVLVGD
NWQILLLDSQVFGVPYGELSDYQLEWMEHCLVAYPERYTLVLLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGRLETEIRRLASDEFCPDMDSDGY
>A0A1S6HXA1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella psychrophila|TrEMBL
MLKEAITYSLGEQASVRIVQVTDPHLFADPNSQLLGVNTAKSLESVLNTIKAVDYPADLM
LATGDISQDYSGESYHNFVRAVAPLDMPCHYLPGNHDDPRVMNLHMQGAKIFGQRRILAG
NWQIIMLDSTVRGKPGGHMSDDEIEIIKSAVADRPERHTLLVMHHNPILVKCRWLDQHCM
DNGSDFIEQVAQIPQVKGLLWGHVHQELDKEHQGQHGIIHLMSTPSTCIQFKPLSSYFAL
DALQPGYRLLELKADGTMMTNVYRVPGDKFSPDRNASGY
>A0A8J8FPF9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylomarinum sp|TrEMBL
MNSPLVILQISDLHILATAEKTLSDVNTDHTFQQLLKQAYAKHGKVDLTLVTGDLAQDPC
QSSYQRIYKALEKYNTRTICLPGNHDDLTLMQQFINGKQTDCSKHIQLKNWQIISLNSKK
EGSEGGYLSSNELDYLCETLQSKPDLNTLIAVHHHPISIDSSWMDGMMIENNEDLFEVLK
NYPQVKAIVCGHIHQAFNTLKENILVLGVPSTCFQFAPNATQFTLDNKDPGYRILKLYSN
GMIESNVYRCSLEQD
>A0A653Q257|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea brenneri|TrEMBL
MDSLLTLPAANGSAIRILQITDTHLFAGKHESLLGVNTWSSYEAVLDAIIAQHRDYDLII
ATGDLAQDHSVEAYQHFAEGISRLPRPCVWLPGNHDFQPAMVDTLADAHINPHKQVLIGE
QWQIVLLDSQVFGVPHGMLSDYQLEWLENALARYPQRHTLVLLHHHPLASGCTWLDQHSL
RNSHQLDAVLQQFPLAKTLVCGHIHQELDVEWHGRRVLATPSTCVQFKPHCTSFAIDTVA
PGWRWFTLHPDGQLETEVNRLDTDIFRPDLDSEGY
>A0A0H2YEX7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia pestis bv. Antiqua (strain Nepal516)|TrEMBL
MASGARVRILQITDTHLFAGEHETLLGVNTFHSYRAVLDAIIAEQHPFDLVVATGDLAQD
HSVAAYQNFAKGISRLPVPCVWLPGNHDFQPAMFDALAEAGIAPSKQVLAGEHWQILLLD
SQVFGVPYGELSDYQLEWMERCLIAYPERYTLILLHHHPMPSGCTWLDQHSLRNAHMLAA
ILTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDAVAPGWRYLDL
LPDGGLETEVHRLDSDEFCPDMDSDGY
>A0A232FCU7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trichomalopsis sarcophagae|TrEMBL
MSSVRGRFSFSNDDGDELQTSLRSLFNGHDPNYNDSSNSQDEKHYMGHRNSIEDVDLHQV
KGPSDVGCNWLTSSITSDNVKILLVFPRDDRQSEVLGLAAQRLGWQISEARDVEEALDLF
ETHSHDVVIIDRRGLHCQQADDICRALNNTHYNRTSVIIALVKRSIFVSSDQDEIATLQI
LDAGFNRALIECSSKEMLMNELIGIFANEVRPKLQLAAAHSLYLAVHRCRDMVHVTNDRH
LIQFANEVSEKLLGWKPDDLINKNLTELVTCENFTLMNQQLQKGREFHGNMNCKRKSNET
ITISSRIIPFCAYGRRPTHYIYIYDTTYLLENIDLTSALPNPVAHLHPRGSSHSLRSFDV
GSIGSDLQRRCSVAKIHNLPLEAPITKVITLLTTAMTEAVSPDVAMQIDKAIEILKTTEL
YAPYVREADELFNDPVTSDLIGALISAPQYSRDSRRSSNDSSGRVSQVQRILHQQTPASK
AAGKGIRAPREIEILLENCMDWDFDIFKLETMSGRRPLYYLGMNVMNHYSVPARLSCDER
TLQNWLTVIEVNYNAQNSYHNSTHAADVLQAIARFMRSERLKLLLDPLDEVAALIAAAAH
DIDHPGKSSQFLCNAGNKLAILYNDLSVLESHHAALTFRLTLSDDDVNIFKNLDRETYKM
IRQNIIDMILATEMTKHFEHLAKFVNVCSIRTEESQSEPFTDPVDSSVLLLPENVSLVKR
MMIKCADVSNPTRPLKFCIEWTKRIAEEYFRQTDEEKRRKLPVVMPMFDRSTCSIPKSQI
GFVDYIINDMMEAWDAFIDLPEMINYMKQNYETWKEYNERGISTLQDVETLQQSPELQIP
QSAQ
>A0A091K625|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Colius striatus|TrEMBL
LTHSLCSVHSFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDL
SPKTMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLL
>A0A6J5B571|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia phenoliruptrix|TrEMBL
MKIRVLSDLHLENDEPELIPHAQADLIVLAGDIHNHAAGPRWAAQTFDGAAPVVYVPGNH
EYYDGEFGALEAALHDAASQVENVHVLNNAALIDPHGRWRVLGTTLWTDFALFGADHAAL
AESIEAARRAMLDFRGLIQMNWPHGVENCARDEARDFAPADALALHRQARAWLENELAKP
FAGQTIVVTHHAPHRLSLAERYAHDRVSAGFVNHLPELVRAPVALWIHGHTHTSFDYTVN
GTRVVCNPRGYFDRRSGQWENPLFAWDKVVEI
>A0A7R8CW13|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lepeophtheirus salmonis|TrEMBL
MVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLQNMVHCADLSGP
TKHIKLYREWCSRIMEEFFQQGDKEKEEGLDISPMCDRHNATIEKSQVGFIDYIVHPLWE
TWADLVHPDAQDILDTLEDNRDWYQSQIPASPSSSSNDLKEEDEGGSTCSSGSSGTESDN
EEETLTPMSSHHHHPPHPSLPGSGSHSSHSHKENKIQFQMTLREEDEETEEKDLESNI
>A0A2A2HIT6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arsenophonus sp. ENCA|TrEMBL
MDSLFKLTTKQKSLVRILQITDTHLFANVDDTLLGVNTFGSFHAVIDAILARNENVDLVV
ATGDLVQDQSASAYQHFAEGIKRLSTPCVWLPGNHDYQPAMVATLAKAGILPSKQVLIND
NWQILMLDSQIQGAVHGKLSKQQLLWMKRCFDAYTERSHLLMLHHHPLPSGCTWLDQHSL
RNSHILADYLNQYQQVKAILCGHIHQEIDEYWQGVRMMATPSTCIQFKPHCTNFTLDTMA
PGWRYLDLSINDDGENVLDTQVFRLDSDKFRPDFDSGGY
>A0A151ULA9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sodalis-like endosymbiont of Proechinophthirus fluctus|TrEMBL
MESLLKLPVARGANIRILQITDTHLFAGENETLLGVNTLRSYSVVLKAVQAEQRHFDLVV
ATGDLAQDHSPQAYRHFATGIAHLPAPCVWLPGNHDFQPAMVDVLAECGISCAKQVFIGD
EWQLLLLDSQVCGVPHGELSNYQLEWLTQTLASQPERYTLLLLHHHPFPSGCIWLDQHSL
HNAHMLADVLQPHPRVKTLLCGHIHQELDVDWLGRRVLATPSTCVQFKPHCTNFTIDTLG
PGWRYLDLLPDGMVHTEVCRLGGTEHLPDTDYEGY
>A0A5E4HFC0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MRLQLISDLHTEFRRGGELAFIQYLPIEKGLDFLVVAGDLVVFAEQGEVIIKAIFGAISE
MARHVIYVTGNHEYYGSTKEWAEEQLREVLSLYPNIHWLDNSEITLDGVHFVGGSMWYPD
VDGLNYVKMYMRMMNDFYAIKLFDWAERENTRFNAFVNGYAGQDTIVVTHHLPHPRCTPL
EFVHSALNRYFVSDQSWTLATRKPKLWLFGHTHREYDGQLSETRLVCNPFGYPGERNSKN
PYKAVVFDV
>A0A1A7Z0K0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Iconisemion striatum|TrEMBL
MRKSRSVLTVSPNNDGKEPPDCCISDSFTSPSCTLGVDLRRGRRRFSGNLQLPPLSWRQG
ERSRTPDIEIMARPTSLPFGAPPRIDITPVDPDSFDVENGPSASCSPLDPQASPGSGLVL
HTNFPGHNQRRESFLYRSDSDYELSPKSMSRNSSIASELHGDDLIVTPFAQVLASLRSVR
NNFTILTNVQCPSSKRSPAATTQPPITKVCLPDEAYQKLAMETMEELDWCLDQ
>A0A669Q2Z1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Phasianus colchicus|TrEMBL
MTQGFDLENGPPGRGPLEPQCSPGAGLVLQGAFTHGQRRESFLYRSDSDYDLSPKAMSRN
SSIASDLHGEDMIVTPFAQVLASLRTVRTNVTVLLHLQERVGTK
>A0A8C1UNM6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyprinus carpio|TrEMBL
MSPDTAKSWLKFAPELDPCIRTFKEHMHLELEPPRLGAGNKRITSPKISPRSSPRLFRKL
MVNKGGRHRRRFTVAHTCFDVENGPSASCSPLDPQASPGSGLVLHANFPSHNQRRESFLY
RSDSDYDLSPKSMSRNSSIVSELHGDDMIVTPFAQVLASLRSVRNNFTVLTNVQCASNKR
SPVSNQPPITRVCLPGKSYNLTPV
>A0A8C2JFT6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyprinus carpio|TrEMBL
MKDHCSSICTAPTGPPFLVMQQRLDPECISVCLLPDESFQKLAVETMEELDWCLDQLETI
QT
>A0A1Z5I5R2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Colwellia marinimaniae|TrEMBL
MNLTETDSPENKPIVLAQISDSHLFSSVNGLHHGHNVLANLRKVLLSICHNRQIDYVIFT
GDLTQDHSEQSYQNFVDLVHECGIAVPIYYLAGNHDEPELLAQYFSAAPFTSDTTIDHPH
WQIQLLDSKSATPAGYVAEQALVKLQKAIKADKHQLVMMHHHPIDVGYFIDKYGLQNKSA
FWQAIDDFDNIKAIACGHVHSAMQLTKQGKQAVKTVHLAPGKSTPAKAPVTLYTCPATSI
QFDPSVDGVAALAKGPGYRIFYLYRNGQLDSDVINL
>A0A8F4GFE4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella sp. PL-2018|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIRASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFTAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQVLLMDSQVFGVPHGELSDFQLEWLEQKLTEVPQRYTLLLLHHHPMPSGCSWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A5C8C282|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp|TrEMBL
MATILSITTKNGGDMSEFHFPVSQHSQRPIRILQISDPHLLQDKHGIFAGIQPFASLQAV
LEHAQKEQLPFDCVLCTGDIAQEPTIQTYQHYLNAVQTLEIPHFWIRGNHDDNADFPEPS
EDHQPKVIVVGQWRIIMLNSQKHGCIHGEISSEQLCFLRDYLQRYPDDFFIIALHHNTFP
VGCAWLDPHRLQNADALLDCLYPHPQVKIVLSGHVHQVFEYQHTQIHFLSCPSTCVQFKP
LQDQFRLDVLAPGYRILELHADGRHDTDIFRLAANLGEIDMQLSEY
>A0A2K6UBJ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Saimiri boliviensis boliviensis|TrEMBL
METLGFGEGAEACSRLSRPRGRHGTARAPKHLWRQPRRPIRIQQRFHSDPDKSAGCREQD
LSPRPGIRKSRLSWPISSCRRFDLENGLSSGRSALDPQSSPGLGRVVQAPVHHSQRRESF
LYRSDSDYDLSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAVLAHQQCRGA
AKQGPVGNLSSSHQPPPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKR
ILNRELTHLSETSRSGNQVSEYISQTFLDQQTEVELPTVTAEEPPKPVSQISGLHGLCQN
ASLSSATVPRFGVQTEQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDL
LKTFQIPADTLATYLLLLEGHYHADVAYHNSLHAADVAQSTHVLLATPALESELALMYND
ASVLENHHLAVGFKLLQAENCDIFQNLSTKQRLSLRRMVIDMVLATDMSKHMNLLADLKT
MVETKKVTSLGVLLLDNYPDRIQVLQSLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGD
RERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLGTLEDNREW
YQSKIPRSPSSLTNPEQGGPDRFQFGLPLEEAEEEEEEGEEPALDKEALELSDTELPPEA
SPDPGDLPLDNQRT
>A0A379CDU0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Phocoenobacter uteri|TrEMBL
MKSVMDYFYQPFAKNESIRILQITDTHLFAKKNEQLLGVNTTNSFQAVLDAILDRQFRFD
LVLATGDLVQDHNEQGYHYFAEMVKPLEKPLFWLQGNHDQLQMEKPLQQYSQIKSQKHIL
VGDKWQILMLDSQVFGVPHGKLSSYQLDWLKVKLAENSERYTLIALHHNILPTHSAWLDQ
HSLRNVHDLAKIVKPYNKIKAIIHGHIHQEMDKLWKGIRILSTPSTCIQFKPHSNNFALD
LIPQGWRELVLHPDGSIDSEVKRLATNEFLPDFSAEGY
>A0A7X8E1S7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonadales bacterium|TrEMBL
MTPQSPNEVVELLQITDTHLFADKEADLLGILPWYSGKAVVAAILEDVLDKQTPVADFIL
STGDLSQDRTSESYYHFCELMAELPSPVFWLPGNHDSGAVMQAALTKAGISHAKHLICGQ
WQVLLLDTHIADKTYGELDAEQLALIACAIESYPKHHLLLAVHHQALPVGCAWLDQHDLR
NSHEMQAILQRHQAAKVVLCGHVHQGFDQQVDGVRYLASPATCFQFKPLSDEFALDSKEP
GWRAISLYPDGRLSTQVWRLPPNSFVPDFSATGY
>A0A1B6E2N9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clastoptera arizonana|TrEMBL
RTDVLVRDEDCDTQVNELAAESNCEPLCHRLQQIKTNSPKQHAFRVLLVFAKDDSACSTL
SGASEHLGFSREVASTLEQALELYQAHSSPPQIVFIDMRFSWFHGEKICRSLRAVKKSNH
VIFVAICKKNVVDKDEKELRSALKLGFNRVLVEPLSITQCVCELVQLAHGQLDLHSILAQ
NEAIYLALDKSRDLVLVTDSLHVIQYVNRTWCQVLGYKSEDLIGRSLHSFHQLGNMDPVT
RQLEKGFDWEGKISWRSKSGENITLQCRAMPYQAIGSEPTHYVYVQDNPLENHIYPRGSI
PSIRKGSYDLKSINSEGAQSARRQSLAKLHNLPLEAPITRVISLICAAQENSTGQVVQIL
DKVVDILRTTELYSSHLKADNLRCEDPVTSDLIGALITVSKLSHQGPVPVSTTRRSSNDS
AAVKAQQAGLSGNKPIFSMSASPQLKELLDTSLQWDFNIFKLEEITGKRPLVYLGMNLLM
HFDVHKTLGCDEKTLYNWLTVIERNYHLSNTYHNSTHAADVLQAMAGFLEKERIKRLVDE
LDEACCLIAAATHDIDHPGKSSAFLCNAGNELALLYNDVSVLESHHAALTFKLTLRDDRV
NIFKGLERDTYKVARQSIIDMILATEMTKHFEHLAKFVSVFNKPSPTSEDGNCDNRFFDS
SSSSDTEIASMVPTFSQHRVDVTSGVFQNHMSPSDCGGDISMLTNADEVNLVKRMMIKCA
DVSNPTRPLKMCVEWARRIAEEYFTQTDEEKANHLPVVMPMFDRTSCSIPKSQMGFVDFI
INDMFEAWDAFIDMPEMLYHLRSNYQYWKDLEEKGVTSLGDISLKQPCSLSPIPNLPNIP
EKHSNAY
>A0A3Q9U8X7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella sp. LY|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVFLGD
HWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A6G8RYY9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter shaoyimingii|TrEMBL
MGSDEKQLEVKEKIIIQITDTHLMDDPNADFVQVNPEQSFHAVIEDIVAKFPHIDAIVHT
GDLAQVAKPETYQRYQAFMTKLNIPFYQVPGNHDHPAFFPFYQPEPNVGVLSFGNWRICL
INTAVHGKIDGWIQSEQLQQLKIILQNQQNTHVILACHHHPLDMQSKWIDRHKLKNTHEL
QQILTEFDNIKLVICGHVHQDSLHAWKTIQFFSTPSTSVQFKPLSDDFALDNIAPGYRSL
HLKENGEFTTQVHRLQNFVQHINKEISGY
>A0A6S7F9K3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter insolitus|TrEMBL
MLIAQITDLHMRTPGDKAYGIIDPAAFLAPAVRALNALTPRPDCVLITGDLTDLGRPHEY
RALRDHLQALEIPYFLLPGNHDDRAQLRAAFPDHGYLQGEGPFIQYAIETYPLRMLALDT
VVPMKSHGELCQDRLDWLAARLAEQPERPTLVLMHHPPFLTGIEHMDAIGLLAGAPELER
IVARFPNVERVLCGHLHRTIFQRFGGTIASTCPGTAHQLALELGPRPTLQYIMEPPGYQL
HWWQGKNLVTHHAVIGEYPGPYPFA
>A0A446D0R4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter veterisilvae|TrEMBL
MLIAQITDLHMRTPGDKAYGIIDPAAFLAPAVRALNALTPRPDCVLITGDLTDLGRPQEY
QALRDHLRALEIPYFLLPGNHDDRAQLREAFPDHGYLQGRGPFIQYAVEAYPLRMLALDT
VVPMKSHGELCQDRLDWLAARLAEQPERPTLVLMHHPPFLTGIEHMDAIGLLAGAAELER
IVARFPNVQRVLCGHLHRTIFQRFGGTIASTCPGTAHQLALELGPRPTLQYIMEPPGYQL
HWWQGGNLVTHHAVIGEYPGPYPFG
>A0A2S9YTV6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enhygromyxa salina|TrEMBL
MRCLPSILTCLTLCTTGLACNDPMEAADTGATGTTGTTGDDVVTEDGEASGDMGDGDGDP
GDGDGDPGDGDGDPGDGDGDPTGDGDGDPTGDGDGDGDGDGDPDAMVRFVALGDAGEGNM
GQYNVAAAMEMVCAERGGCDFAVYLGDNFYNDGVDSVEDEQFMTKFEMPYADIDFPFYVV
MGNHDYGELSFVWDKLEYEIEYTNYSDKWILPAKWYSVYDFPNVDLFAMDTTRLMWNHET
GAQQAWLDAELANSDAPWKIAFAHHPYYSNGEHGNAGNYEGWPFPPQLAGTTVKKVIDES
VCDKVDLVLSGHDHNRTWNQLTCGGGERTTYFIVSGAGCKNTDFAHHDDNPVHWEEDTTP
GFLLVEVELEKIHTAFYDETGALNFERDIVK
>A0A517E036|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sporomusa termitida|TrEMBL
MIDYNVTNLNQAVKIMLSHIYVESGLSDNGTLVYGEAEGAGIRIDLLNFFFSYKFSEEDE
DTWGNIIHKVKIDEYEAIEALYHYLVSGLEKKGLICRVHDVFKKDLDIKLTLDGYKYWTK
LVQKKQKVEIFSDSKITNTNEEIAVETFQIPKVELCIPNEDEEKIRINILEILYDYKNQF
EKKMYFEELSLRFFSQYNSDLSQYKYWSEVKSLFDKETISTAKSYVEARVIQCFRENLLY
YDFRNFTAVEITKEGIKYLKKSKGDIASSDKVTVDEEQIERGNSERIKIIHISDLHFGSL
ENDGLDNKDKSKDVLKVKQPAFEAFSRILPTIYDANTFMAISGDITSKNEEAGYIQCQKA
IEKLGINLQRIYLVPGNHDCNKSSTPQTQYANFLCYFQDYFSPVNRNRRYLIDDEQKMFI
IGFNTIYSCDSDFIFIEEQEMQSFKQLIDELSEKISGFSTYTRIAVVHHNLNPHPNIEIN
QYKDILNIFQLKQILMEKKFKIVFSGHQHQPMIERQQIYIEDLNGDILLVSAGSLSGKIR
NNRNSFQVVDLERDIKSGVLFNIIIDEYELKLGEFKYKNRVNLPLV
>A0A553QG27|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Danionella translucida|TrEMBL
MTVLKRLNTHYLLFYLSSFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYR
SDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFAALTNVQQERTNNK
RSPMCNPPPITKTSYTASCSSKPLEFYLPSEAVRVSDPDRKIPLQLFIAAFLSVEPVPSH
GLVYDVALSTRRMSLTSAQALAGILSLSPACSGTARLHACASRGSCAHVRLATLLGCPSL
VQGIHCLEKRGQANARSFVLFCDRTGDRHKTLICWRQPSVCFAFVLVCVCERVYVCVIVM
TLCLCALLWAGLHTPEGQRTTLGFSDVDRHLSRRDDGPTFFFGSIWSPIFHCGGLQHSMK
NHPCVLSGYPNMAVYSRLGPLLGASARPLQHLRSDCLLHSLPPEEAYQKLATETLEELDW
CLDQLETLQTRHSVSEMASNKVRTSSSLSLAEFTLEALG
>A0A2K5IDM3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Colobus angolensis palliatus|TrEMBL
MPRSGQFKRILNRELTHLSETSRSGNQVSEYISRTFLDQHTEVELPKVTAEEAPQPMSRI
SGLHGLCHGASLSSATVPRFGVQTDQEEHLAKELEDTSRWGLDVFKVAELSGNRPLTAII
FSIFQERDLLKTFQIPADTLATYLLMLEGHYHADVAYHNSLHAADVTQSTHVLLATPALE
AVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQ
AKNCDIFQNLSTKQRLSLRRMVIDM
>A0A2I0FYW3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacterales bacterium CwR94|TrEMBL
MDSLSMFPVSSGAKFRILQLTDTHLFAGKHETLLGVNTWSSFEAVLDTLVAEQRPYDLIV
ASGDLAQDHSPEAYQHFVDAIARLNAAPVVWLPGNHDYQPTMVTTLANGAGISDTKHILV
GDAWQVVLLDSQVPGVPHGELSDYQLEWLERTLSAHASRHTLIFLHHHPMPSGCTWLDQH
SLRNSHMLEAALQAFPLAKTLVCGHIHQDLDLNWNGRRLLSTPSTCVQFKPHCTNFTIDT
VPPGWRWLTLGPDGSVETEVQRLQTSRFTPDLDSEGY
>A0A2H5X371|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR16|TrEMBL
MRSRRFIFRRGFLLLLLLTAVSVVTGTWWGERIEITHLRLPLNEAGDNFRLAVLSDIHIG
SGGKGMERWRRALDSVEKERPDAILLVGDYVTSHAGIPALQNAFRNIHAPLGVYAVLGNH
DHWAGSKAITGILEQQGIHVLTNRAVRLRKGNGELWIVGIDDLWTGKPNWQEAFRGVPRN
AAIVLLSHNPDAAITPYRERADLILSGHTHGGQMWLPLARVLARVFDFALIPHSEYGSRY
PHGLRR
>A0A2H5X305|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR16|TrEMBL
MPGHLRFRQETFKIVQFTDTHWTNFDERDRRTRQVMEVVIEHEKPDLVFLTGDMLGGADC
KDAARGMLQLIEPVEERGLPWTAVMGNHDDEGTLSREELWRVMESCAHFVGKRGPRNVTG
VGNYVLPIMNRKGERPAAFLWGIDSNSYATTDIGGWGWITRDQIAWYVRTARRVRQQWGI
TDEERSRIPALAFFHIPLPEYDEVWRTQVCYGEKHEDVCAPKINTGFFAALHEVGEVIGT
FVGHEHINDFWGNLYGIRLCYGRGSGYGGYGKEGFLCGARVIELQEGARDFRTWLRLEDG
TAILHQPEHLPATAEPQCCHAE
>A0A5E7GSX8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAGADGTLLGMNTRDSLQQVIELARLQQPRIDLIIAS
GDISQDGTLESYQQFRDLTRQLDAPARWIPGNHDEPRIMAEAAVQSALLEPVVDVGNWRV
TLLDSAVPGSVPGYLEVEQLQLLARSLSEAPERHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFSVLDRFPQVRAVLWGHVHQEIDRERNGVRLIASPSTCIQFEPGSDDFKVSDQAPGYR
WLRLLPGGELETGVERVTGFDFQVDYGSGGY
>A0A5E6QX42|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTVNPDTALLVQLSDSHLFAEADGTLLGMNTRDSLQRVIELVRQQQPQIDLIVATG
DLSQDGTLESYQQFRDMSAPIGAPARWIPGNHDEPQIMAQAAAHSDLLEPVVDVGNWRIT
LLDSAVPGSVPGYLQDSQLQLLAQALSEAPGRHHLVCFHHHPVPFGCAWMEPIGLRNPDA
LFAVLDRFPQVKAVLWGHVHQEIDLERNGVRLLASPSTCIQFAPGSEDFKVSEEAPGYRW
LRLHADGRLETGVERVEGFDFTIDYGSNGY
>A0A5E7NTE8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLSSAEPALLVQISDSHLFAEADGTLLGMNTRDSLQKVIELVQAQQPQIDLILAT
GDLSQDGTLESYQQFRDLTRQLDAPARWIPGNHDEPQIMAEAAVQSALLEPVVDIGNWRV
TLLDSAVPGSVPGFLQDDQLQLLVRALSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQVRAVLWGHVHQEIDQLRNNVRLIASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGQLETGVERVTGFDFQVDYGSDGY
>A0A3S0LV47|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas veronii|TrEMBL
MPRVPTVTPDAPAVLVQLSDSHLFAEADATLVGMNTRESLQRVIGLVREQQPRIDLLLAT
GDLSQDGTLASYQHFREMTAPFGVPARWIPGNHDEPQIMAHAALHSDLLEPVVDVGNWRI
TLLDSAVPGSVPGYLQDSQLQLLAQALSEAPHRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVRALLWGHVHQEIDRERNGVRLLASPSTCIQFTPGSEDFNVSTEAPGYR
WLRLHADGRLETGVERVKGFAFTVDYASNGY
>A0A0A1XQ71|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Zeugodacus cucurbitae|TrEMBL
MGCSPSTLLSHNNPDADDAHPAADTQLSGAGTALAASGGNGEKDSSLFFCIKLRRSRPLR
RCSQQNGGGDGSAGSGGTGSAINGDELLGHGNMCNQALLNPAQTKNEADYDKICSGKKDS
IVTVAALGNFTHTVVRRATGSTGTSGTTSSGGASKPEKRKSSIALTPEDESIERSLMDVK
FPTVLPPNPQLKALLVFHKSDNICEVITEACHRQQLDVTVARTKEGALDTLTNTNEEFYH
LIIIDARSTKHLDAEYIARSIRHTNGHHFTTIIAVVKKSFFEKDDVLIALLDAGVNRCVP
ETTNLSMCNIELKQILHSIVRPHNVMSTQQALYTALHRLKEVILITDNHLRIQYANRAAE
RLLNMRMDEIISKPLADIFISDVSTIMIHGRKNKEFDEILTVRRKGQEDVAMHVRVIPVA
CIGRTPTHYVFNLDVPGSHGDFVATLPQAREAPRGSQHSIRRGSVDVRSVASDGLRRTSL
AKLTSLPLEAPITKIINLLSQVQENCSPDEARLIDKVMEFLKREGLYSPQMKEIRTDDPI
ATDLIGALLTGPSLYSSRRSSNDSIIRVGGRQSTCMPAKMKATPHIMELLEESLSWEFDI
FKLEEITEKRPLLYLGMEMFRRFNVFATLNIDENVCKSWLAVIEANYHANNSYHNSTHAA
DVMQATGCFLTQLAAKDMGMDRTDEAIALIAAAAHDVDHPGRSSAFLCNSRNTLALLYND
LCVLESHHASITFRLTLSDDKVNIFKNLDTESYKSVRSVVIDMILATEMTRHFEHLAKFV
SIFGSDEEPKDIVQSEEESSILIRRMMIKVADVSNPSRQPSYCIEWARRIAEEYFTQTDE
EKAKTLPIVMPMFDRNTCSIPKSQIGFIEYIIQDMMHAWDSFIDMPQLVTYMQINYSQWK
KFEDQGVHTLADVKSKQHSLSVKKSAK
>A0A3T0VTA2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hahella sp. KA22|TrEMBL
MASDKNQALTVIQVTDSHLRREPDGTLLGMNTRRSLDAVLSLVRANHENPDFVLATGDIA
QDGSTEAYECFHEKMQPFQCPVYWFSGNHDDPGVMAKAVRNPECLAKVKIFGPWKLIFLD
SSVRRKVYGKLAKKELQLLKAELEKDQDKHVIICFHHHPVDVDCAWLDTIGLHNRDDFFA
VIDGYEHVRLILWGHIHQEYDQMRNGVRLLATPSTCVQFKPYSEDFAVDTLAPGYRWLKL
YPDGRVETSVVRASHIEFEVDLSSKGY
>A0A6S7ET71|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter anxifer|TrEMBL
MLIAQITDLHMRTPGDKAYGIIDPAAFLAPAVRELNALNPRPDCVLITGDLTDLGRPHEY
QALREHLQALEIPYFLLPGNHDDRAQLRAAFPEHGYLQGEGPFIQYAIETYPLRMLALDT
VVPMKSHGELCQDRLDWLAARLAEQPERPTLVLMHHPPFLTGIEHMDAIGLLAGAPELER
IVARFPNVERVLCGHLHRTIFQRFGGTIASTCPGTAHQLALELGPRPTLQYIMEPPGYQL
HWWQGGNLITHHAVIGEYPGPYPFA
>A0A3N1IV80|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. BIGb0383|TrEMBL
MESLLNLPLAGGARVRILQITDTHLFAQKHETLLGVNTWESYQAVLAAIHAQQRDCDLIV
ATGDLAQDHSAEAYQHFAESIAAFAMPCVWLPGNHDFQPAMYSALQEAGISSAKRVFIGD
HWQILLLDSQVFGVPYGELSDYQLEWLERKLADAPERNTLLLLHHHPLPSGCSWLDQHSL
RNGAALDTVLARYPRVRHMLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTIA
PGWRWLELHDDGTVTTEVCRLQSTQFSPDTASEGY
>A0A4W3GX95|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Callorhinchus milii|TrEMBL
MRTLGVYKERKYEGSEDFELENGASGGRSPLDTQPSPGSALVLQTTVPSQGQRRESFLYR
SDSDYELSPKSMSRNSSIASEMHGDDLIVTPFAQVLASLRSIRSNFSLLTNVQGATGRYL
PQCWGAVLGGRSAGGWGSAGGGAVLGGSAEWEHWW
>A0A4P7KPZ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arsenophonus nasoniae|TrEMBL
MDSLFKLTTKQKSLVRILQITDTHLFANADDTLLGVNTFASFHAVIDAILVRNENVDLVV
ATGDLAQDQSAQAYQHFAEGIKRLSAPCVWLPGNHDYQPAMVATLAKAGILPSKQLLIND
NWQILMLDSQIQGAVHGKLSKQQLLWMKSCFDAYTERSHLLMLHHHPLPSGCTWLDQHRL
RNSHILADYLKQYQKIKAILCGHIHQEIDEYWQGVRMMATPSTCIQFKPHCTNFTLDTMT
PGWRYLDLSINDAGEDVLNTQVCRLDSDKFCPDLDSGGY
>A0A330ERX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGD
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLTGAQFRPDTASEGY
>A0A443X9C3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas caviae|TrEMBL
METELPQAPDGSVRLLQITDTHLFASAEGRLLAVPTAQSLAAVLERVQAYEHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHHGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRVASQVWRLPLGQFVPDPNATGY
>A0A443XLB6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDHVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLHADGTLTTEVCRLTGAKFRPDTASEGY
>A0A6S4ZGW0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas caviae|TrEMBL
MRLLQITDTHLFASAEGRLLAVPTAQSLAAVLERVQANEHPFDLILATGDLSQDHSPESY
QRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGDHWQVILLDTQVRGKP
HGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNADDLFAVLARHSQ
QKTILFGHVHQEFDEVHHGVRLIASPSTCIQFKPLSDGFALDESGPGWRYLTLHPDGRVA
SQVWRLPLGQFVPDPNATGY
>A0A1H9FAL0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rosenbergiella nectarea|TrEMBL
MNSLVPEIADNRSIRLLQLTDMHLFKTPQESLLGVNTWQSYQAVIDAVIAEQRQIDLIIA
TGDLAQDHSPEAYHAFAKGIRRLQKPCVWLPGNHDFQPAMVKTLASEGVCDQKSVLLGDQ
WQLLLLDSQVHGVPHGLLSDYQLQWLGDALARHPQRHTIILLHHHPIPSGCTWLDTHSLR
NSHQLAEVLQDYPLAKTVVCGHIHQEMDDLWQGRRVLSTPSTCVQFRPQCTGFTIDNQSP
GWRWLELRPDGEVVTEVQRLFGPQFQPDFHSEGY
>A0A4R2FFR6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella fodinae|TrEMBL
MLKEAITYRIPKDHSVRIVQITDPHLFADPEGHLLGVNTANSFAAVINTIKALNYPADLL
LATGDLSQDFSGESYQSFVKAVGPLNLPCHYLPGNHDDPRIMHLHMQGKQIYGQRRILAG
NWQIIMLDSTVRGKPGGHLAEEEFAIIRSAIEAVPELHVLLVMHHNPIKVNCAWLDQHWM
DNGDEFLQQMAKLPQVKGMLWGHVHQQLDSHYQGEQQSIALMATPSTCIQFKPQSPYFAL
DVLQPGYRLLELRADGSMLTNVHRIPGERFAPDIQASGY
>A0A6M2ADG9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Anoxychlamydiales bacterium|TrEMBL
MNIFAISDLHLSFSVPDKSMEFFGPSWKDYQKKIEINWKNTISKDDLVLIPGDISWAMKL
KDALIDLEWLNNLSGKKIIIKGNHDYWWPSKTKLQKALPPSISFIQNDAINFDDISIASA
RLHDTKEFNFNEYINFVKNPRAKKALEEDIQKDLSEKLFAREIERLKLSLEKLNKNAKTK
IVMTHYPPISATLKDSKVSKLLEENKIDKCVFGHLHNLKENVKMFGEKNNVKYILASADY
INFTPIKIL
>A0A735IS47|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella typhisuis|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>Q0T0M5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella flexneri serotype 5b (strain 8401)|TrEMBL
MESLLTLPLAGEARGRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7D6NX23|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia rettgeri|TrEMBL
MDSQLKVTANNPKVIRILQVTDTHLFADTENTLLGINTYRSYQAVLDAIAEQNLPVDLIV
ATGDLVQDQSPKAYQHFAAGIERIPAPCVWLPGNHDYPPAMVGTLKIAGISSAKQVFIGD
DWQILMLDSQLQDVAHGELSEQQLEWMKQCLDEQPTRTTLIMLHHHPLPSGCTWLDQHSL
RNSHILADYLKNYPNVKAMLCGHIHQEMDENWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELTVNEQGEKVIETQVYRLNTQEFSPDFDSDGY
>A0A644TVX5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MAVFRNGNGIAWARRRALIWALFALAFCAAMNIYHYSLQGAWGLYLWDKTWLFRILILMG
LLPLGLLILSFPLEKLKTKAPAKLLRGFSLVASFLVSLTSLGILAFLIVTPRMGSLRQVQ
LNLIDPSIKLESSAGAEDGKTLLRLSVGSDAHWGTDKTDSNARSNILASIAEHRPDIFFL
LGDTVETGSSVSQWNAALADLSAIAPRVPLRPLMGNHDALFGGQYLYKKAFFPREFSSDS
GSPYYYSMDTGAATLVALNLPWGTENFGRKQKTWLESVLSAADPLKPLIVFSHSFFYASG
YDDPKLDKPWYDHYKNIPALTPLFERYGVDLVVSGHNHYMEYLEKNGVRYAVVGAMGSKS
DPEPEYISPASKWIAVATFGHLNIDITSNDVVLEFKDQLGKTLREVRFPYTPSLRSGNDE
TSPQT
>A0A644WQH8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKMKGIFILLLTCFALQLTAQQPTLRFNKQGSFKIVQFTDLHYSVEKETVSAAALECINK
VLDLEKPDLVVFTGDLVYSKPAKEGLTRVLKPVVDRKLPFAVVWGNHDDEQDLSRAVLQS
VVEQMPGCLGKKTDGIPGESNFILTIQPNSGNQASAVLYFMDSHAYSALPQVKGYDWIKP
AQIQWYIDASKRFTDANEGKPLPALAFFHIPLPEYNQAASSENSHLVGYRFEKPCAPELN
TGLFTAMLTAGDVMGVFVGHDHDNDFVADWKGIALGYGRFSGGNTEYNNLPEGNGARVIV
LKENTRDFTSWIRLRSGEIMQNIQLSKLIKPAKKD
>A0A645CJ91|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MIPGNHDMGQKPTEKNIEFYFRHYENDKFNFIHKNIQFIGINSCYINSENENEDIQFHWL
KKNLESNPQNLRRIVFTHHPFFIRDIDEKDNYSNIPLQKRKLYMDLFVDNNVKAIFSGHY
HNNAESSYKSVDMITTSAVGKQLGQAKSGFRIVKVYSDSLSHEYIEISNLPKKIKL
>A0A644ZLM8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MAHTSRKSNTTRLLCLLATCLLLFSSCSDNLISRIEFNHPGGSFDQAIDTTEARESFSFL
VFSDLHYGRTESGFYLEEEAFLAWLDTYPSTLAFALHLGDGTAYSLESEYRLYRDFLDML
EDRSIEVHAVLGNHDVRADGRSLFTRYIHHLTARRFSYKGISFYLLDTGNASLGKVQLDN
LMSSVADDPNPKIFCGHVPLYGGPDMFYFSLKDPHERALLVKTMVQNKVGLYLGGHLHIE
LIRCAEASKTSCS
>A0A7Y8U655|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. SwsAc4|TrEMBL
MTFQVSKLSQKDFVIIQITDTHLLEYPHLEFVGMHPEQSFHAVIDLMRQQHPQIDMIVHT
GDLAQNPTTVTYDRYLKHMQSIGIPFFQTPGNHDDVSHFPFHGADPHQPIVVEIGDWCII
LLNSAQPTRIDGKIAETGLEQLTELLKKHHDRHIMIACHHHPFAMESAWIDQHKLKNSSD
LLETIQPFSNIKAIICGHVHQDSINTWQDIQFLSTPSTCIQFKPKSDKFALDEEHPGYRF
IKLKANGEIETQVYRLSTSQRMNSSEVLGYD
>A0A6P8L8X9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bombus impatiens|TrEMBL
MGCKTSMLECIEDTGEAEKRKHSDMVNQGSLLGKTEYDVLRRRSSFEDVAVDDDENADCS
ALKGPQNIEAHPLTNSVPSLIKILLVFPKDDQQMDVLATTSRRLGWSVSVAKDAEKAVEF
FQNRGHELVIIDHRGQRAAEADTICRYGELFFKNQSNSSDVRLYILINTIYFRAIRSSPA
YHNSIIIALVKKSFLMHGEKDKIVTLDLLETGFSRALMECSHERLLINELVGIYASALLP
RTQLAAANALYVALDRCRDMVHVTNDKHIVQFVNKISEKLLGYKTSEILGKSIADIVVYD
NFVLMEQHISKGREFEGNMNCKRKNNQMITISCRVIPFSINLKKPTHYIYIYDTTYLSEN
IGSLSPTPSQSVYSRGNMIVSQRRTSDMKSSEGRRRSSAHKLHSLQLDAPITKVISLLSN
AITESTTPDTAAQIEKAIDILKTTELYVPSLREDTDPVTTDLVGALLASPRKAWESRRSS
VESTRVSTSKAFTTTTASRMQIKSFRGPQEIAEILERCLEWNFDIFKLEILTEKRPLLFL
GTTIMNMYRVPARLGCEEKVVQNWLTVIEMNYQSRNSYHNSTHAADVLQATARFMQSERL
QQILEPLDEVATLVAAAAHDVDHPGRSSQFLCNSDNKLAILYNDLSVLESHHAALTFKLS
LSDDNVNIFKNLERDTYKQLRQTVIDMILATEMTKHFEHLAKFMNICSARMMDSPQLDDY
TDTVDMSVVLQPENVVLVKRMMIKCADVSNPTRPLKCCVEWARRIAEEYFNQTDEEKRMQ
LPVLMPMFDRATCSIPKAQIGFVDFIINDMVEAWDAFIDMPEMVGYMRQNYEKWKEYNPK
KMKDTVIESYF
>A0A8C3NRL0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Geospiza parvula|TrEMBL
FVYEGNKKIEVNYCLCITDILLLNNSQRFQTNLPGKPFTVVLQCAFYFLSAQWSRDRSVS
LTQKLILKPLFLFQVLASLRTVRNNFAALTNLQDRAPSKRSPMCSQPSINKATITGKNNL
FIKTI
>A0A1F2M403|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella sp. HMSC16C06|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQASGISPAKRVFLGD
HWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDRALSAWPRVRHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAEFHPDIASEGY
>A0A812A478|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Methanoperedenaceae archaeon GB37|TrEMBL
MVKDEKIKIAHVSDLHITGPNFVSQWGENVIDILNSEMPEILIITGDLTDDGYVHEYELA
KTYIDRIKVKNKIVVPGNHDARNEGYIIFEEIFGTRCPYYENEKVVILGIDSSQPDIDDG
HVGRENYGLIREKLSINNKVKILAMHHHLIPIPGTGRERNIPSDAGDVLKICMELGVNFV
FSGHKHLPWTWRLENTYLITAGTATSRRLKGRSYPSFNILEIPAIHADKQDKMAILKEVN
VTNKKFREILRGFRALKNVETPLV
>A0A7Y4ZA12|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methyloglobulus sp|TrEMBL
MRDSSRPISILQITDPHILATPEATLLGINTAYYFNAVLEHALNPVRSFDLCLVTGDLAQ
DPCQASYQHILTTLQAYNIPCMCLPGNHDDFVMMQEVLRTDTINCRKRQVLGSWQIIGLN
SQIPGSEGGYLALEELAFLEQFLRDCPDFYTLIAVHHHCLPTGSLWMDTMMIENAQKLFD
VIKPYPNVKTIINGHIHQAMDVQINSVRVLTTPSTCFQFRPKSERFNLDDASPGYRWINL
YADGNIATGIVRIPEQLAGFQADTQGY
>A0A399PN70|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. 91RF|TrEMBL
MPSVSTLTTADAALLVQLSDSHLFAEADGALLGMKTRESLQKVIELVLEQQPQIDLMIAT
GDLSQDGTLESYQQFRQLTAQIDAPARWIPGNHDEPQIMQMAAVQSALLEPVVDVGNWRV
TLLDSAVPGSVPGYLQDDQLQLLARALSEAPDRHHLVCFHHHPVSIDCAWMEPIGLRNPE
AFFEVLDRFPQARAVLWGHVHQEIDRERNGVRLIASPSTCIQFEPRSVDFKVGEQAPGYR
WLRLLPDGRIETGVERVTDFRFTVDYGSNGY
>A0A7Y3VJT5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. A11|TrEMBL
MNVSPSLDPSDNIKLVQITDTHLFAADDGCLLSVNTADSFHAIVQAIIEQKVAFDALLAT
GDISQDHSAESYQRFASEISALQKACFWLPGNHDYKPNMGSVMPSSQLHAPEHVLLGKHW
QMILLDSQVVGVPHGRLSDYQLNLLDEKLAQHPDRYALILLHHHPLLVGSAWLDQHTLKD
SDAFWSVIQRHQNARAVLCGHVHQDMDRTFAGVKVMASPSTCVQFKPNSDDFALDQCSPG
WRELELYADGQVTTQVKRLARGAFVPDFTSNGY
>A0A5E7MDW8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPRVSTLTTADPALLVQLSDSHLFAEADGTLLGMNTRDSLQKVIELVRLQQPRIDLIVAS
GDISQDGTLESYQQFRDLTRQLDASARWIPGNHDEPRIMAEAAVQSALLDPVVDIGNWRV
TLLDSAVPGSVPGYLEDEQLQLLARALSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPE
ALFSVLDRFPQVRAVLWGHVHQEIDRERNGVRLIASPSTCIQFEPGSDDFKVGDQAPGYR
WLRLMPDGELETGVERVTGFAFQVDYGSNGY
>A0A1Z9HN91|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium TMED163|TrEMBL
MMPQTANSPIHLVQITDTHLYGKATGTLLKMNTHDSFEHVIELVRGKEDRIDLILATGDI
AQDASESAYGHFADRVGTLGAPYRWIPGNHDKAEVMKNAAATPDVDEKSVQINNWLILML
DTSTDGQVHGNLAPGELEFLHSQLQESKLNNSIEHIMICMHHNPVKGNSGWMKDIGLKNR
ARFWELAETATKIKCVVYGHIHQELDFVHGNIRCLCSPSTCIQFKPNVVNFALDQVNPGY
RSFELHANGTVESEVHRVEGENFEADFSSGGY
>A0A6S5Z6F9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas veronii|TrEMBL
MRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQANEHPYEVILATGDLSQDHSPESY
QRFASMMAPLGRPIYWLPGNHDDSPLMTEYLHAAGISESKQLVGDHWQVILLDTQVRGKP
HGMIGDHQLAALDRALRQYPDRHALITLHHQAVPVGCAWLDQHNLKNADDLFAVLARHPQ
QKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLCDGFALDESGPGWRYLTLYPDGRVA
SEVWRLPVGQFVPDPDATGY
>A0A285B9K0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella grimontii|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQILLMDSQVFGVPHGELSDFQLEWLEQKLAEVPERYTLLLLHHHPMPSGCSWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLDLHPDGTLTTEVCRLEGVKFHPDIASEGY
>H3RA01|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea stewartii subsp. stewartii DC283|TrEMBL
MDSLLTLPATTESEVRILQVTDTHLFAGKHESLLGVNTWASYDAVLDAIIAQQRDYDLIV
ATGDLSQDHSVEAYQHFVEGISRLPKPCVWLPGNHDFQPAMVDTLAEAGINAHKHVLLGE
HWQVVLLDSQVFGVPHGMLSDYQLEWLNTTLARYPQRHTLVLLHHHPLASGCTWLDQHSL
RNPHQLDAVLQHYPLAKTLVCGHIHQEMDVPWQGRRVLATPSTCVQFKPHCTSFTIDTVA
PGWRWFTLHNDGQLETEVNRLTTQAFRPDLDAEGY
>A0A8B6A4Z4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter hormaechei|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEKRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGD
QWQILLLDSQVFGVPHGELSDYQLDWLETKLAAEPNRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDGVLAKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLAGAQFRPDTASEGY
>A0A0L7T3X6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia iniecta|TrEMBL
MDSLLKLPVSSGDNIRILQITDTHLFAGKNETLLGVNTWASYDAVLDAIEAEGRHYDLIV
ATGDLAQDHTVEAYQHFAEGIARLPVPCVWLPGNHDFQPAMFNTLAEADIADAKHVLLGE
SWQVVLLDSQVFGVPHGMLSDYQVEWLENTLAQQPQRHTLVLLHHHPLPSGCNWLDQHSL
RNPHALDAVLQHYPLAKTLLCGHIHQELDLDWNGRRILATPSTCVQFKPHCTNFTIDSVA
PGWRWLDLFADGRVATQVERLQTQDFSPDLDSEGY
>A0A0H3NM24|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella typhimurium (strain SL1344)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A1C2Q065|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter pittii|TrEMBL
MTFQVSTLSQKDHVIIQITDTHLLEYPHLEFVGMNPEESFHAIIQQILNKHPEIDAIIHT
GDLAQAPTPITYNRYIQYMQTLGLPFFQTLGNHDNVDHFPLHKENHQEPVVICLGNWRVV
LLNSAVKGHIDGHLSAEQLENLTTLLEEYADNPILLACHHHPFAMKSKWIDHHKLQNSNA
LLTTLAPFKNVKALVCGHVHQDSINTWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLKKDGSFETEVFRLENFQGHINTDISGY
>A0A427E041|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. v388|TrEMBL
MALSSAAPSSSVLLVQLSDSHLFAEADGTLLGMNTRESLAKVIDVVLAEQPAIDFIIASG
DISQDGSVESYEAFRTLSGRIAAPVRWFPGNHDELPQMEQVARRGGLLEPIIDTGHWRIT
LLDSAVPGSVPGFLEPAQLELLEKSLSQAPNRHHLVSLHHHPVSIGCEWMEPIGLRNAEA
LFAVLDKYPQVRGVLWGHVHQEFDQLRNGVRLLASPSTCIQFAPGSIDFKLDTTAPGYRW
LRLHDDGCLETGVSRVQGMTFEADYGGAGY
>A0A7Y1IM36|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas panacis|TrEMBL
MPSVSTVNPDAPALLVQLSDSHLFAEADGTLLGMNTRESLQRVVELVRRQQPHIDLMLAT
GDLSQDGTLESYQQFRALTAAIGAPMRWIPGNHDEPQIMAHAAVHSDLLEPVVDVGNWRV
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPSRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVKAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFSVSEQAPGYR
WLRLHADGRLETGVERLVGFAFTVDYGSNGY
>A0A078LL77|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter koseri|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTRESYQAVLDAIHAGQHEYDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVFIGD
QWQILLLDSQVFGVPHGELSDFQLEWLERKLADAPERHTLLLLHHHPLPSGCSWLDQHSL
RNAAELDSVLANYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIG
PGWRTLELYAEGSLETQVHRLPGTQFRPDTASEGY
>A0A2R3EV05|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. WE21|TrEMBL
MLKEAVSYSIAEGESVRIVQVTDPHLFADPEAQLLGVNTSKSFAAVLNTIRAVDYPAHLM
LATGDLSQDYSAESYQQFVKAVTPVGLPCHYLPGNHDDPRIMYLHMQGEQIFGQQRILAG
NWQILMLDSTVRGKPGGNMAETQFELIDEAIAAHPECHTLLVMHHNPIVVNCTWLDQHCM
DNGAEFIARVAKYPQVKGLLWGHVHQCIDTHHNGPHGTLQLMATPSTCIQFKPLSPYFAL
DGVQPGYRLLELKADGSINTKVYRVPGNHFSPDNNSSGY
>A0A671SCZ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sinocyclocheilus anshuiensis|TrEMBL
PREAGGGKSKGHEAKETVSPMAMQQDFHGAPLSVCLCPDESYQKLAVETMEELDWCLDQL
ETIQTYRSVSDMASNKVRRCSTSLLRASLEVVKTLRGCLRSKARSRTFS
>A0A0H3NKP8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia enterocolitica subsp. palearctica serotype O:3 (strain DSM 13030 / CIP 106945 / Y11)|TrEMBL
MESLFKLPMASEARVRVLQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGISRLPAPCVWLPGNHDFQPAMVDALANAGIAPSKHVLVGD
NWQILLLDSQVFGVPYGELSEYQLEWMERCLMAHPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLNWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGRLETEVRRLASDEFCPDMDSDGY
>A0A169CFB1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella oxytoca|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQILLMDSQVFGVPHGELSDFQLEWLEQKLTEVPERYTLLLLHHHPLPSGCSWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A5E4VWI5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea nosoerga|TrEMBL
MSQSSPGSRASQASPPLSAPTASPSPPGAAHAHGKPSRRTLPARPRWLMLAIIALLHAYI
GWRLLTPLPVAPGWKVLGAAWLVASTVLIPLGLMSRAIQREPLATLLTWAGMTAIGIFSS
LFVLTVLRDVVLGVALAVSGVDAQLATRSAIIVLVLTAVSTLLGFYNARRLARVVEIDVP
IADLPPALKGFTIVQLSDIHVSSTIRRRYIEAIVEAANELKPDLVAITGDLVDGGVPALR
EHIAPLARLTSRHGTYVCTGNHEYYSGAPAWVEELRRLGLTVLENEHVVLDHEGAALTIA
GVTDFTAHHFDPAKRSDPMAAAAGSPEGVPRVLLAHQPRSAPAAQEAGFDLQLSGHTHGG
QFWPWMYFVPLQQPFVHGLHRLGRLAVYVSRGTGYWGPPKRFGAPSEITRIRLVPGNA
>A0A7H4NWI1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella grimontii|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTLESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQILLMDSQVFGVPHGELSDFQLEWLEQKLAEVPERYTLLLLHHHPMPSGCSWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLDLHPDGTLTTEVCRLEGVKISPGYRFRRILMSTLLYLHGFNSSPRSAKATALER
VAGADLS
>A0A0L7QMN5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Habropoda laboriosa|TrEMBL
MGCKTSMLECIEDRGETEKRKQTDMLDQGSLLGKAEYDILRKKSSFEDVTAENDEDADYS
TLKGPESIEAHPLTNTVPSLVKILLVFPKDDQQMDVLATTSRRLGWSVSVAKDAEKAVEF
FQSRGHELVIIDHRGQRAAEADMICRAIRSSPVYHNSVIIALVKKSFLMHGEKDKIVALD
LLETGFTRALMECSHERILINELVGIYTSALLPRTQLAAANALYLALDRCRDMVHVTNDK
HIVQFVNKISEKLLGYKTSEILGKSIAEIVFYDNFILMEQHISKGREFEGNMNCKRKNNQ
MITISCRVIPFCVSLKKPTHYIYIYDTTYLSENIGSLSPAPTQPPFIRANAVVSQRRTSD
IKSTSESRRRSSLHKLHSLQLEAPITKVISLLSNSITESTTPDTAAQIEKAIEILKTTEL
YVPSLREDTDPVATDLVGALLSSPRKAWESRRSSVESGPRYSAVKAIASNIAASRMQIKG
FRGPQEIAEILDRCLEWNFDIFKLEILTEKRPLLFLGMTVMNQFRAPARLGCEEKIVQNW
LTMIEMNYQAQNVYHNSTHAADVLQATARFMQSERLKQILEPLDEVATLIAAAAHDVDHP
GRSSQFLCNADDKLAILYNDLSVLESHHAALTFKLSLSNDNVNIFKNLERDTYKQLRQTV
IDMILATEMTKHFEHLARFMNICSSRIADYQQAYSDTVDMSVVLQPDNVVLVKRMMIKCA
DVSNPTRPLKCCIEWARRITEEYFSQTDEEKKLKLPVQMAMFDRLTCSIPKAQIGFVDFI
INDMVEAWDAFIDMPEMVGHMRQNYEKWKEYNMSVVPLIFRDWWDDFDRPVSRLMDQHFA
RGLNKEELVSRFSDLSLDRPLRSIFRDRYYRPWRNVTREHSSGSSTVQIDSQDNFQVFGG
DATIACGRESRAISIVITRRYEPYLLSGDNRYGCDYSFDSSVNYGYGSKVILDVQQFSPE
EITVKTVGNNVIVEAKHEEKQDEHGFVSRHFIRRYQLPSSHDTINVTSSLSSDGVLTITA
PKKGETPAGTERIVEIVKTGEPASKPIKIETTTE
>A0A2S1B9M7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Morganella morganii|TrEMBL
METPLHLPVADGAAVRILQITDTHLFAGETDTLLGINTLSSYHAVLDAIVKQQLPADLIV
ATGDLVQDQSTRAYQRFTDGIARLPAPCVWLPGNHDYQPSMAQELAAAGISPSKQVLLGD
QWQILLLDSQVQSVPHGELSDDQLIWLDNCLAQQPDRHTVVMLHHHPLASGCTWLDQHSL
RNSHMLAEVLTRYQNIEGILCGHIHQDLDVMWNGIRMLATPSTCVQFKPHCTNFTLDTAA
PGWRYLELTTGDSPSLTTQLFRLDTDEFSPDLGSDGY
>A0A6I3W2P7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas spelaei|TrEMBL
MPSVSTLNPDAAALLVQLSDSHLFAEADTQLLGMNTRDSLQRVIDRVLARQPKIDLLLAT
GDLSQDGTLASYQAFRDMTRQIPAPARWIPGNHDEPQIMAHAAINSALLEPVVDVGNWRI
TLLDSAVPGSVPGYLQDRQLQLLAQSLSEAPTRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVKAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEEAPGYR
WLRLHADGRLETGVERVEGFVFQVDYGSNGY
>A0A1W4ULL4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila ficusphila|TrEMBL
MRNCLPKFSKVFRRKSSAKSSSTGGLGRENPSNEPDSDTEPYAIAAIADRGGDNRNERPL
PDDDSSRRRLISVAHLNSDSDLPANGKGVPFSQHRSTDEGSCPEMKVETISTTTATTADS
VPLASGQAAISQPFAGRNSSKTPEEMELEYEATVEAESRDIMTPLRRNTRPLSVSFGAGR
TALQPEIVEAIRSLDVPALLLNNLNLDGGRGAEVETRSQSHSQSQSGEMSPGHELEDSVV
LRRKVNCLERKAHSLYERRLPKVPKLHLLVAGKKSKADEEREAEAEELRTFQRNLMDLKY
PTVLPPNPPLKALLVFHKSDSICEAVTAACQRHQLDVTLVKSKEEALDTLQKSYATAQCY
HLIIIDARSTKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCV
AETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRAT
ERLLNMRLDEIISKQLEDIFVSDLSTISEQCKSIKEFDGILTVRRKSQEGIPMHVRVVPV
ACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTS
LAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDP
IATDLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTASIVPAKMKSNPIIMELLDESLSWD
FDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNST
HAADVMQATGAFITQLTNKDMMMMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAV
LYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHL
AKFVSVFGGEEPRDHNSQTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFM
QTDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMIHAWESFIDMPQLITYMQINY
SQWKKYDEQGVNTLAEIMAKQPPVGKMANSK
>A0A6D1W0B4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. JMN1|TrEMBL
MPSVSTVNPDAPALLVQLSDSHLFAEANGTLLGMNTRESLQRVIELVRAQQPQIDLMLAT
GDLSQDGTLESYQQFRDMTRQVDAPARWIPGNHDEPQVMALAAMHSDLLEPVFDIGNWRV
TLLDSAVPGSVPGYLQDRQLQVLAQALSEAPSRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDHERNGVRLLASPSTCIQFAPGSEEFQVSEQAPGYR
WLRLHADGRLETGVERIKGFTFTVDYGSNGY
>A0A2M4A7Z6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles triannulatus|TrEMBL
DQDDADADDGDDPLLDGGTSSSSGRYGHRKSSLALTPEEEPLDSCPRLVSDLKFPNLLPP
NPAIKILIAFCKNDPVFEALVNASHRLSFEPTFVKSAEAAIDAFQNPTAGGHHIIIVDAR
YPRIIEAEALGRSIRNSKGSQHTTMVAVVKKSVFEKDDTAVISLLDVGYNRCIIESPHVS
ICSSELRQIQHSLVRPQNVISTQQALYTALHRSREAVIITDDTLRAQYANRASERVLNMK
LDEIVGRSLGDLVTADISNILSHTSRYKDYDGYLTTRRKSQESSQIHVRAVPVSCIGRNP
THLVLILESSASALASISAAGEALQTLPQGKEVARGSLHSIRRPSFDVRSIASDGLRRTS
LVKLSSLPLEAPITKVLSLLAQVQENCSLEEAKLLDRVMEFLKREGLYSPQMKEIRPEDP
VATDLIGALLTQGPTNILSSRRSSNDSIIRGGGRPSTGSIVFNKTKESSQLSDLLHTALD
WDFEIFKLEELTDKRPLVCLGLELFRRFDVYNTFNCDEMTFKLWLIEMEKNYHSENTYHN
STHAADVMQATAVYLQQLSNRELKIMDRMDEATALIAAATHDIDHPGRSSAFLCNSDDML
AVLYNDICVLESHHAATTFRLTLADDKINIFKHLDRDSYKLARSIIVDMILATEMTRHFE
HLAKFVSVFGTDVESKEPLPPDNDDNQILVRRMLIKCADVSNPTRPLRFCVEWARRIAEE
YFMQTDEEKRKALPIVMPMFDRTTCSISKSQIGFIEYIIHDMMDAWNSFIEMPEIVRYME
FNYSQWKLFEEQGINTLSDIKRKQLSLAEEPSSIISLEEKF
>A0A3Q8UHR0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter baumannii|TrEMBL
MTFQVSKLSQKDFVIIQITDTHLLEYPHLEFVGMHPEQSFHAVIDLMRQQHPQIDMIVHT
GDLAQNPTTVTYDRYLKHMQSIGIPFFQTPGNHDDVSHFPFHGADPHQPTVVEIGDWCII
LLNSAQPTRIDGKIAEAGLEQLTELLKKHHDRHIMIACHHHPFAMESAWIDQHKLKNSSD
LLETIQPFSNIKAIICGHVHQDSINTWQDIQFLSTPSTCIQFKPKSDKFALDEEHPGYRF
IKLKANGEIETQVYRLSTSQRMNSSEVLGYD
>A0A5E4WCZ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea terrigena|TrEMBL
MSQPSQASSTSPPSPDAAHAHGKSPRRALPARPRWLMLALIALLHAYIGWRLLTPLPVAV
GWKVLGGLWLVASTALIPLGLMSRAIQREPLATLLTWTGMTAIGIFSTLFVLTVLRDIVL
GVAMVISAIDAQLVVRSAVIVLMLTAMATLLGFYNARRLARVVDVDVPIANLPPELHGFT
IVQLSDIHVSSTIRRSYIEAIVEATNKLSPDLIAITGDLVDGGVPALREHIAPLAQLTSR
HGTYVCTGNHEYYSGAPAWVDELRRIGLTVLENEHVVLAHEGASLTVAGVTDFTAHHFDP
AKSSDPLAAVAGAPEGVPRVLLAHQPRSAPAAHEAGFDLQLSGHTHGGQFWPWMYFVPLQ
QPYVHGLHRLGRLAIYVSRGTGYWGPPKRFGAPSEITRLRLVVGTA
>A0A3B7CV26|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. dhg|TrEMBL
MQSSSDSIKLLQITDTHLFEADEGSLLSVKTADSFSAVVGEVLRREVGFDYILATGDISQ
DHSAGSYQRFAAGIAPLEKDCFWLPGNHDYKPNMGSVLPSQQIKATEHVLLGDKWQVILL
DSQVVGVPHGRLSDKQLTLLEEKLAEYPERYTLVLLHHHPILVGSAWLDQHTLKDAEAFW
QIVERFDGVKGILCGHVHQDMNVLHQGIRVMATPSTCVQFKPNSDDFALDTTSPGWRELE
LHATGEITTQVNRLPEGQFQPDFSSNGY
>A0A5B7XJ50|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Leclercia adecarboxylata|TrEMBL
MESLLNLTVAGGAPVRVLQITDTHLFANKHETLLGVNTWESYQAVLEAIHAQKRECDLIV
ATGDLAQDQTAAAYQHFAEGIASFNAPCVWLPGNHDFQPAMYSALQDSGISPAKRVYTGD
NWQILLLDSQVFGVPHGELSDFQLEWLEAKLEAEPARHTLLLLHHHPLPAGCSWLDQHSL
RNSASLDQVLEKFPRVKHLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLQGTEFRPDTASEGY
>A0A2N7CYN2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. 10N.286.49.C2|TrEMBL
MKTTPSGESQSSAVRLLQLTDTHLFAPPDGCLLSVNTHDSFNAVVSEVCKQGAHFDALLA
TGDISQDHTELSYRKFVEGIVPLQLPCFWLPGNHDFKPSMNSVLDSPLIETATHKLLGEH
WQIVLLDSQVVGVPHGRLSDQQLDYLDQILTQHSDRHTLVLLHHHPILVNSAWLDQHSLK
DSQEFWEIADKHDNVRAVLCGHIHQELDQLRCGVRVLATPSTCVQFKPNSNEFSLDTLSP
GWRELELFDNGQLNTTVKRLPHGAFRPDFNAEGY
>A0A6G8J4Y6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurellaceae bacterium Orientalotternb1|TrEMBL
MQEPYHFPDLASIRILQITDPHLFTSEDGQLLGVPTIRSFGAVLNAILREPFQYDFILAT
GDLVQDHNREAYHRFANMVKPLAKPIFWVEGNHDLQPQMSNALSMYAQIQPHKQVLAGEK
WQVILLDSHLPDRPKGELSQAQLNFLAEKLAAYPDRYALIVLHHNILPTNSAWLDQHSLA
NADQLADVLSDFPRVKGILHGHIHQEVDQMWHGYRVLATPSTCIQFKPNCDKFTLDPIPQ
GWRELILHPDGTIETQVKRLDCNDFLPNFNAQGY
>A0A2U0TH81|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurella langaaensis DSM 22999|TrEMBL
MTNTYIYSSDIDVVRLVQVTDPHLFKDESGELLGINTLASFNQVLTEIQASDFAFDLVLA
TGDLVQDSSDEGYLSFAERINTLNKPVFWIPGNHDFQPKMESFLTEQYGHLCTKKHLLLD
NKWQILMLDSQVFGVPHGKLGQYQLDWLADRLKEYPERYSLIVLHHHILSTNSAWLDQHN
LRNSEELAQTLAPFSNVKGILHGHIHQQVDATWNGYTLMSTPSTCVQFKPDCNSFTLDTL
QPGWREIELHSNGEIVTRVKRIEQASFLPNTQEDGY
>A0A5J4RGS8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MKKLLLLCFTCAWSCLQLSYAQSSPLKFNSNGKFKIVQFTDLHYIYDNPGSDIALERVNE
VVDAEKPDLIIVTGDVIYGKPADKSMRAVLDVLAKKKTPFVVLFGNHDDEFGLSRSQLFD
IIKSYPYNVTTTVEGLSGIGNCIFSLKGTNGKDEAILYCLDSHAYSSIEGI
>A0A5J4RCL5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MKQLAISFVTMALLLCTSVNADPPRFAVMSDIHFGNNKGKGPMVKVPQALKNIFSKGPLD
ALFIVGDLTQDGKEEEYDQLNAVFNDKTIVPEGIAVYFLMGNHDNHSENARAIYLNQLHQ
PLHQYIEIKGYPFITVSMTEKIVSGKPSMDYNTEAQTFLSEKLAEAAKKYVGKPIFVFFH
VPPLNTCYGSTEGSWGSDILVPILKQYPQIIAFTGHSHMPIGDPRSIHQDKFTVVNDGST
TYSGVEKGEVSEGTHPEGYSDITEGIIVNVLKNGNIQMERWDTYRNEEILPKWVVKAPFD
GSNFTYKNRNGLPAPSFKRKAQPIVSNIDSQSYTVTFPQATDNEVVHHYMVEVLEGEQVI
ASFRKFSQFYLNSQMPAELSQKLTELPEGKTLVVRVKAVDSYKNMSAPIISKPFFTSVSD
TKPTARFAVLSDTHFGNSTSMTKVPQLLKVLFSKKPLVDAVFVVGDLTHRGKREEYEQLM
SVFTDKSLIPEGVAIYFMMGNNHDNHDKTTGIEHYLEITKQPLHHYVDIKGFPFIAFSEG
GSKLNEFNEEMKDWLAKTMADAATKYPGKPIFAFSHVSPENTCYGTLSSEGWGTDIFLPV
YNQYPQTVVFGGHSHYPIGDPRSINQQVFTSINDGSSYYSEVAPGEVSMGIHPEGYGNVT
EGLIVNVFPNSDIEIERWDTYRDKEIMPRWEIKAPHDGSRFRYKNYNGLPAPVFAANAKI
TGEQDGNSYKITFSQAADNDVVFRYFIELLDTAGKVVYSYTKFSQFYLNSDMPDELSHTF
SDLPHGKTFIPRITAADSYNNLSKPLTGEVFTTPLQ
>A0A5J4PYA9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
VLVTHGAPWGILGGETYSCPILRDVVDEAQPRIHIFGHIHNYGGQTLQHGKTLFCNVAVT
M
>A0A833ABS2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cholerae|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFAVEDGSLLSVNTADSFAAVVAAIGEEQVEFDVILATG
DISQDHTPESYQRFVCGIQPLKKACYWLPGNHDYKPSMHSVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEYPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRIHLGARVMATPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A1X3JCT3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli H386|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>R9PKN5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Agarivorans albus MKT 106|TrEMBL
MHLLQVTDTHLFADEQTGLLGVNTNDSFSAVIENIKSDNIPFDYILATGDLSQDHTKRSY
QRFAERIAELERPCVWLPGNHDMQENMLTLEQHGVLAAKQLVSEHWQIIMLDTQLEGEPH
GIMSQRQLDNLAEALAEYPDKHVLIAMHHQAIPVGSKWLDQHNLKNADEFFAVIADFPNV
RGVIFGHVHQNYEFQFDGIAFIATPSTCIQFLPLSANFALDHQQPGWRYLQLTAEGRIAT
RLRRLSERSFLPDPKSKGY
>A0A7D8B4U3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio spartinae|TrEMBL
MDVSFYTEHFDSIKLLQMTDTHLFASDEGSLLSVNTANSFKAVVQEVIARNVDYQLILAT
GDISQDHSQASYQLFVDSIEPLQKPCLCLPGNHDEQHAMKTILANSQITQPRHVTVGAHW
QMILLDSQVSGVPYGYISPEQLQQMDDMLRETQAKHTLILLHHHPLLVGSRWLDQHTLKN
SDSFWEILLKYPHVKGVVCGHVHQVMERDYHGIQVMSTPSTCVQFKPHTDEFALDLVSPG
WRELELHPDGQLTTQVGRVKQGLFLPDFSANGY
>C0PYV4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella paratyphi C (strain RKS4594)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>K8WJC4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia sneebia DSM 19967|TrEMBL
MDSQLEVTARDAKVVRILQITDTHLFADTANTLLGVNTHKSYHAVLDAILEQNKPIDLIV
ATGDLVQDQSPQAYQRFATGIERIEAPCVWLPGNHDYQPAMVKSLKMAGISCAKQIFIDD
DWQILMLDSQLQDVPHGELSEQQLEWMKSCLDNYPQRTTLVMLHHHPLPSGCTWLDQHSL
RNAHILAEYLKNYPQVKAMLCGHIHQEMDENWNGIRLLATPSTCVQFKPHCTNFAIDTLA
PGWRYLELTIDAEGNKQVSTQVHRLNTQEFSPDLDSDGY
>A0A6S6Z5H1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter kerstersii|TrEMBL
MFHVFTGLISLYVIWRFVLPLSLSRTSKLLLSVLLMAAAEHHLVTRNLFGSMASPEIPGT
LLMVLGWLFGSLLLLAMLLLARDVAGSVVYLFSRVRGKRLWAARGWGVGAAVASVVLSAI
GVWQAVRVPDVKTLEIALPKLPPELDGFRLVQLTDLHASRLLEAPWMEAVVTKTNGLNPD
LIVITGDLVDGTTDARAADVLPLQALRARYGVYAIPGNHEYYAEYQRWLPAFEKLGLRLL
LNEHVTLTPNGQRLVLAGITDKMAAAYGQLEPDVARAMDGVPATDPVILLSHRPIGAVRN
AQAGAGLQLSGHTHGGQILGPHLLTQLANEGYVSGEYQVDGMRLYVSNGTGLWPGFPVRL
GRPSEITQIVLRSPAKTAAQ
>A0A090T8S4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio maritimus|TrEMBL
MNTTPSDESQLSSVRLLQLTDTHLFAPDDGCLLSVNTQDSFHAVVAEVMQQGIPFDALLA
TGDISQDHTEASYQKFVDGIEPLGLPCYWLPGNHDYKPCMNSVVSAPLIQDVTYALLGEH
WQVLLLDSQVVGVPHGRLSDSQLDFLDRKLTEHSDRHTLVLLHHHPMLVNSAWLDQHSLK
DAHEFWQVVEKHNNVRAVLCGHIHQELDHLRNDVRVLATPSTCVQFKPNSNEFALDTRSP
GWRELELCADGEVKTTVKRLPHGAFRPDFNAEGY
>A0A8C3TRF1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Catharus ustulatus|TrEMBL
MDRRPQRQPEYMSVCLFAEEPYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKVSPR
ADTIRDCLGSTIRDIVESPVAAAGSFPEIKEVSISARPLEPM
>A0A2Z6V2M3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcystis aeruginosa Sj|TrEMBL
MRPFWLESLQVERLTIAIAGLPAHLQGIKLVQWSDLHCDAQHLPVAVLQEAIAITNQEKP
DLIFLTGDFITDSPQPIFALVDSIKALESQGGIYACLGNHDSYLPHARETVRSALTSVGI
RVLWNEIVTPYGENFPIVGLADYWSGEFLPQILEQISPDIPRLVLSHNPDTAMILKDWRV
DLQLSGHTHGGQVTIPGIGSLPIILEELRRSLPEPYGQWVPLHRQFSRVVRYWQWSEGFH
RVGENQLYVNRGLGTYFPGRLFCPPEVTVITLINSSQ
>A0A8B6GIQ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mytilus galloprovincialis|TrEMBL
MAAAAIYRKFKKLGLVPKHGKKHNHGHPRVKHPDDDDEEDRDTFDVENGTGPGRPTLEGS
SPSSSRLVLQNLPQRRESFLYRSDSDYDLSPKSVSRHSSMQSEIHADDLIVTPFAQILAS
LRSVRNNYISLTNVQAPRER
>A0A833MX97|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alkalilimnicola sp. S0819|TrEMBL
MPTAATSYSGAGAPLRVLQITDTHLYADPGGRLAGLVTEQSCEAVINEALQRSWPVDLVL
LTGDVVHDGSESGYRRVKARFEQLGVPTLVLPGNHDAPVTMRQVFRAGPVSYCAHHALGD
WQFLMLDSTVAGESGGHLAEAELRRLDEALSADPRRHALVALHHHPVSMDSRWIDSIGVA
NAEALFAVLARHPQVRVLLWGHVHQAFDEVRDGLRLLATPSTCIQFRPRQDEFGLDEQPP
GWRLLELHADGRVDTEVQRLNAGDLAVDLRCSGYV
>A0A3M1RWM8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MAYRNERLAVSHRVLRLLQLTDSHLHASPDARMRGFNTDESFRAVLAQAMRDPDPAEAIV
VTGDLVQDETRAGYERLREMLAACELPVFCIPGNHDAPELMASVLSAPPFQLNGDWQIGN
WRLIFLNSYCRGDDGGRLPREELQRLADGLQQENADHYAIFLHHQPVPMGSRWLDGVGLR
NADELLEIVDGSSRVRGLVWGHVHQASDRRRHGVRLLSTPSTCLQFLPNSDDFALDSRPP
GYRWLDLHANGRIDSRVAWLEEN
>A0A7H8SD47|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. NEB 394|TrEMBL
MTLNNEKNWTIIQISDTHLMDQDHLEFVRMNPEQSFHHVIQHIVERHPQIDAFVHTGDLA
QVPVPRTYQRYLDFMQSLKTPFYQVPGNHDNAEHFPFHQQQNKVHVIHFGPWSVVLLNSA
VKGKIDGWVDEAQLNQLEQILQEFAQQHIVIACHHHPFEMQSKWIDQHKLKNTQDLTAVL
AKYHNVKIVLSGHVHQESWREWHSIQFYSTPSTSVQFKPLSDHFALDEQAPGYRILQLNA
DGSHETHVERVLHAQQKINVEISGY
>A0A384KYN5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella flexneri|TrEMBL
MESLLTLPLAGEARGRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A2J8KKZ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pan troglodytes|TrEMBL
AFQGSRSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKS
MSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINK
ATITG
>A0A0H5FGI3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia enterocolitica|TrEMBL
MESLFKLPMASEARVRVLQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGISRLPAPCVWLPGNHDFQPAMVDALANAGIAPSKHVLVGD
NWQILLLDSQVFGVPYGELSEYQLEWMERCLMAHPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLNWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGRLETEVRRLASDEFCPDMDSDGY
>A0A315VEH6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gambusia affinis|TrEMBL
MTIDEGGNGDRPVNRELRFLTQLSLYHDRPVQRPLDGRRCANSTVEILELLHLVQDSLTR
RRHSTLFQLKTMASDLEALILIPAASHLAANRFSESCRSRHDEANRTTSSAKSRDSILRL
PKRMHSTPWLLLEILSIKIMNRIGDKGQPWRPTLTGNKPNLLPAMWTRLRHPSYRDLTAP
ASSSSSPRLHLLMMKEHCTRVAQLKFHPLPQQPQQSHAAGGQHSGSMYSVCSDSVSLCTG
CLTDEAYQKLAMETMEELDWCLDQLETIQTYRSVSDMASNKSETDTLTDGRPAQVCTPRS
AIMGACCFDRKDKKLGKLSFWKKSRSSQPRVRRDPVQAYLSAWLPCTASCPMKSHLNAGA
QRWVSPLTHHSRAGQIKMPQASFTFPASVMAALC
>A0A077PHT7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus bovienii str. kraussei Quebec|TrEMBL
MESLLKVPVAEGATARILQITDTHLFASKGDALLGINTYRSYHAVLDAILEQSIDIDLIV
ATGDLVQDQTIGAYQNFAEGIARLPVPCVWLPGNHDYQPAMVDVLAAAGISPSKQILIGQ
YWQLVMLDSQVQGVPHGELTDYQLEWLQKCLDEHNDRNTIVMLHHHPVPSGCTWLDQHSL
RNAPALAESLKDKRQVKAILCGHIHQELDKMWNGIRVMATPSTCMQFKPHCTNFMLDTVA
PGWRYLELSVAGNREAKLQTQVHRLKSNEFCPDLDSDGY
>A0A564G3R3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium dankookense|TrEMBL
MRIWILSDLHQGVGGPPWNPARIPEADVVVVAGDVCEGLGAAVDWAAEALGRHMPVVMVA
GNHEFYRRIHGEELALGRAAAQAAGIHLLEDEAVTLGGVRFCGATLWTDYALDGLERRRA
AMDAAGRGLNDHRRIRWGHARRPFRPEEALGLHEASRAFLDAVLRETPGGLHQVVVTHHG
PAPASVAPAFAGDPLNPAFVSDLGPMIEDRRPALWVHGHVHASLDYVHAATRVICNPRGY
GSENPAFRADLVVEVGA
>A0A7Z0Y4F8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. diarizonae serovar Rough:r:z|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLVLQANGVLETEVHRLQDTRFRPDTASEGY
>A0A7L8QDE6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella quasipneumoniae|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVFLGD
HWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALRAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A3S0VXE8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Competibacteraceae bacterium|TrEMBL
MSTAHPLRVIQISDFHLQSAPGSRVWGVDVDAGLGAVLAHIQKHHPQPDFVLATGDLVGD
QPEAYPRVRQALETLGVPVYCLPGNHDVPAAMGQVLRTGQVRWARYVEAASWQVVLLDSS
VANSPTGHLAYRELTLLDTALAAHPERHTLVCLHHNPVPSGTAWLDTMMVGNHSALFALL
DRHPQVRALAWGHIHAEFSDQRGALRLLGTPSTCVQFKPDSAVPEADALPPGYRWLELHA
DGTLHTGVERVEISVRNLALTRRVPA
>A0A6F9B8U8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Coregonus sp. 'balchen'|TrEMBL
FDVENGPSASCSPLDPSASPGSGLVLHTNFPGHNQRRESFLYRSDSDYDLSPKSMSRNSS
IASELHGDDLIVTPFAQVLASLRSVRNNFTVLTNVQCASNK
>B3RT43|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trichoplax adhaerens|TrEMBL
MGERKQYRMILAIFSENDKQLNALKQAAEKGNYKLNVVHSERSAIEYYQDYRPHIVFVDL
RSKDAFNGETICKNVKDKSLSNQSTMIAVVNPSNSDKEEPSIAPLLAMGFNRRFVENFNV
GGCLNELIMLEVNDLRQQVKIREADSLFAAIHNAYDSVEITTDRSQFQYVNPAFERTTGY
WSSELIGKLDSVLPTSDKNDPELFNTIKSYVSRGRTWEGSYVGKRKSGETYPQFVRVIPI
IGHEGFLTHHVTIKRDISEMETKYKKYVEESIKSYPNGKVVDPNHIKTVEASTSMVINLI
KIAQENVSESPNNVTQSLDKVLQILKDAEISFPQGADFDLINFTELGNNTITSQGNLPRP
SLVVNAKSILNDASAEIKIALDGASDWDYDILELERVTEKRPLVYLGMKIFERFRMGHYL
NASADVLCNWLKLIEANYRQSNSYHNSTHAGDVLHASACFLDCDRVKNLLDPLDIMASLI
AAIVHDVDHPGVTSAFLCNSHNPLALLYNDSAVLESHHAALAFKLTTSNDKVNIFKGLES
DEYRSIRSSIIDMVLATEMTKHFSYLSKFTDCLNASKNTVIADDGTELKVIESSSENRML
AKRILIKCADISNPARNWILSKEWALRILDEYMCQYDEEDKEGLPLTMHMFNREKCNVPQ
SQRSFYDYFVKDLFKSWHSFAHIPHVMKNIEENYDHWRNVEQKGIKIYNLKNEREIHNVV
YWRSLIFDLKIVEKSFAVTYVMN
>A0A4P9VJI4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Zooshikella ganghwensis|TrEMBL
MSADNSNNTVTIIQITDSHLFQTADGRLLGMNTQDSLKEVIKKIQLDIDNVDLILATGDI
SQDGSLRSYKEFARLVNGMGVSSYWLPGNHDEFRVMAQLFAGKTNLYKKITTGNWQIIML
NSTVPGKVFGQLSQAELNFLNTSLKNAERPNVLVCLHHHPVPVNSAWIDQIGLRNAEALF
ETLANYDSVRAIACGHIHQEYDQVHDGIRVLASPSTCVQFSPGSETFQADESAPGYRVFR
LGADGQIDTFVERVTHIDFEIDYSVKGY
>A0A5Q0TKD0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio algicola|TrEMBL
METISTTQDVVTFVQITDTHLFSDEKGALLGVNTFDSFTAIVQDIQTQDIACQALLMTGD
VSQDHSDGSYQRFEQGIQPLNKDCYWLPGNHDYKPSMSSIYPSAQIKQATHLLAGEHWQV
ILLDSQVEGCPYGELSAQQLEYLAQKLAEYPQRYSLILMHHHPKLVGSEWLDKHCLHNSE
QFWQVVAPHSNAKAVLCGHVHQDFHQQHNGMEVITSPSSCVQFKPNSNEFAVDKIAPGWR
SLSLLPNGDIETQVYRLSGTDFLPDFDAEGY
>A0A177XUA9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio bivalvicida|TrEMBL
MKVTSSSSDSDSIKLLQITDTHLFEPADGSLLSVNTLDSFHAVVSAIIEENQPFDSIIST
GDISQDHTAESYQRFEQGIAPLEKTCFWLPGNHDFKPSMTSVLPSTQIKQIDHVLLGEQW
QMVLLDSQVVGVPHGRLSDHQLALLEEKLTQYPERHTLVLLHHHPLLVGSRWLDQHALKD
ANHFWDVVEKHQNVKAVLCGHVHQDMNVLYNGVRVMATPSTCVQFKPNSDDFALDTLSPG
WRELELHADGQLTTQVKRLPYGCFQPDFNSAGY
>A0A7G9YUN7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methanosarcinales archaeon ANME-1 ERB6|TrEMBL
MQRSEGGSEDENMRIAHISDIHVVEPHFLPDLAEKVIEKINEIEPEIVVVTGDLTENGYP
FEFERAKSYIERIECKVKVVIPGNHDARNVGDFCFEEIFGSRSKVERYEGITIVGVDSTQ
PDIDDGHVGREKYEWMEKCLDTNDFKVVALHHHLISVPKTGRERQIPIDAGDVLELLIRC
GTDLVLCGHKHVPWIWNLNGMIITNAGTACTNRVKWNIPQSFNLIEIDEEEKGTIKIYRM
YSKGGQELVLEKRREKAMR
>A0A5I4TW96|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Adelaide|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A432RKI5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylococcus sp|TrEMBL
MTLATTLTLKTDSSRRDQTVELVQITDLHLLADPQGLLLGVSTDDTAREVFKFAQSKDWP
PDLVLLTGDLAQEPLPETYRRLNELLRSLKTPCVCLPGNHDDPSTMSEQLRGDNVRCLSR
VLTDHWQIICLNTSLPEKEGGHVSEESLSQLETLLDEQPDRFALVGIHHPPVSVGCSWLD
TMIVDNGDKLLELVRSRPQSRAIVCGHIHQALHLRDRGLEIFGTPSTCFQFMPDSEKFAL
DELGPGYRRLSLFPDGRIESEVYRLPGKPRGLDQSAAGY
>A6VML5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / CCUG 43843 / 130Z)|TrEMBL
MINTYQYDTDSDEIRILQITDPHLFKDAGSELLGINTCASFNQVLTEIQASPFEADFVLA
TGDLVQDSSDEGYLRFCEMVQPLGKPVFWLPGNHDFQPKMNELLNKNHGNICAEKQILAG
EQWQVLLLDSQVFGVPHGNLTEYQLDWLQNKLKAQADRYVLIVLHHHLLSTHSAWLDQHN
LRNANELAQILAMSDNVKGIVHGHIHQTVDDLWNGYRVMSTPSTCIQFKPDTNHFALDTQ
QPGWREIILHTDGSIETYVRRIRQASFLPNMSEDGY
>A0A2N7FK55|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIKPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAVLCGHVHQDMNRNHQGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTQVRRLPNGQFSPDFDAGGY
>G0AXY9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella baltica BA175|TrEMBL
MLKEAVSYSIAEGESVRIVQVTDPHLFADPEAQLLGVNTGKSFDAVLNTIRAVDYPAHLM
LATGDLSQDYSAESYQQFVKAVTPVGLPCHYLPGNHDDPRIMYLHMQGEQIFGQQRILAG
NWQILMLDSTVRGKPGGNMAETQFELIDEAIAAHPECHTLLVMHHNPIVVNCTWLDQHCM
DNGAEFIARVAKYPQVKGLLWGHVHQCIDTHHNGPHGSMQLMATPSTCIQFKPLSPYFAL
DSVQPGYRLLELKADGSINTKVYRVPGNHFSPDNNSSGY
>A0A4P8BXV7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O145:NM|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A829Z759|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|[Clostridium] cocleatum|TrEMBL
MNEYDLINCYLNLIFDDSITYFNRILDGYHGLCQFKEWMRKRNINLNAIKNIDYDTFMAI
SKAKRIDQITERIDPRHLQELIDYINIERDKYQIVVLSSFDYNESINIYLTSKQMIKDFS
NDKVSIINCHSLLEKDDLTFYGPFKHFVSALYQIDRWPGLLIFKGEDCSFVPVYTIKDIQ
EVMFKINHDTVFSSKYLSPYDSYFVQLSDLHLGSKRKNQGRLALEESLDETCKQLRSYYQ
LKFLITGDLMNSPNRKNMYEASGFMKLLKNKYSGDVSFILGNHDVIVNGFNVFKRQKSKV
IAFLLNESIKVFEEEKIILIKIDSTVEGNLARGKVGQKQLSDIDEELENIPNLQEYTLVA
MLHHHLFRITRDEFLKQRWREKVFVGKIMDSSKALVDSQELVWWLRKHQIQYVLHGHKHL
PFFNNHDGMYVIAAGSSCGSGAKESDSRYLSYNVLKYSHRYKCFKYCFIVYDDMTLQDRQ
RIIVNMF
>A0A085GK24|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Buttiauxella agrestis ATCC 33320|TrEMBL
MESLLNLPVAGGGQIRILQITDTHLFSGKDETLLGINTWMSYQAVIDAILAEQRHYDLIV
ATGDLAQDHSAEAYQHFVEGIAEIPAPCVWLPGNHDFQPAMFSSLLEAGISPAKQVFLGD
NWQILMLDSQVFGVPHGELSDYQLDWLERKLAGSPERHTLLLLHHHPVPAGCSWLDQHSL
RNAAELDNVLQKFPKVKTLVCGHIHQELDLDWNGRRMLATPSTCVQFKPHCANFTLDTIE
PGWRWLELHPNGEVTTEVCRLKGAVFNPDTASEGY
>A0A8I1BRB9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteus hauseri|TrEMBL
MESQLELSVKHKNTVRILQITDTHLFANVEDTLLGINTYRSYHAVLNAIREQGLDVDLIV
ATGDLVQDQTFEAYQHFADGIATLTPPCVWLPGNHDYQPAMIDALNQAGILSAKQVLIGD
NWQLLLLDSQIQGVPHGELSDCQLDWLTRCLESQKHRETIILLHHHPMPSGCTWLDQHSL
RNSQELAERLRNHSQVKMMLCGHIHQEMDEMWNGIRLLATPSTCIQFRPHCTNFTLDTVS
PGWRYLEMSLSSDEKGKIETHVHRLAGTEFCPDLDADGY
>A0A5E4S282|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea pneumonica|TrEMBL
MGGRTTDEAKHGGGSGEVPELSAQYRSEGESTPIDARPDAAHAEAAPGTSGMSRRRAMAC
LAWAGAGILWTLDGGVPRGVSFGTQAQAATTAPSGNALSFVQISDSHIGFNKAPNPDPAS
TLQSAIDRIRNAPQRPAFMLHTGDVSHLSRPAEFDTAQQIVTGAGLETHYVPGEHDVIGD
DGRAFFARFSPDTKGLGWYSFDQNGVHFVALVNVLNLKAGGMGYLGDTQLAWLADDLKAR
SRSTPIVVFTHMPLWTVYPAWGWGTDDGDRALALLRPFGSVTVLNGHIHQVLQKVEGNVR
LQTAMSTAFPQPAPGDGPGPGPKQVDPSQLRQTLGIRRVDFTALDGTPLLADTTLAS
>A0A6M8MMT6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas graminis|TrEMBL
MSSASSHPSSVLVVQLTDSHLFAEADGALLGMPTRASLDAVVERVLGEQPAIDLVLATGD
LSQDGTVESYQAFRDASNRLSAPTRWIPGNHDELREMAIAAQNSDFLEPVVDIGHWRITM
LDSAVSGSVPGYLQDGQLQLLAQALSEAPERHHLVCLHHHPVPIGAAWMEPIGLRNPEAL
FAVLERFPQVRAVLWGHVHQEFDQLRDGVRLMASPSTCIQFAPNSVDFGLDDLAPGYRWL
RLHDDGRIDTGVSRIAPDLFDVDINGAGY
>A0A8C5VZY9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcebus murinus|TrEMBL
MGCAPSIRISEARAAEVALGPAGPPPSGGPCLTQGHRTAALPPARGASLADSEPRDGSGK
KVAVAEVQFGPMRFHQDQLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTREAQAVLACFL
DKHHDIIIIDHRYPRQLDAEALCRSIRSSELSENTVIVGVVRRVAREELSVMPFLAAGFT
RRYIENPNIMACYNELLQLEFGEVRSQLKLRACNSIFTALEKSQEAVEITNEDHIIQYAN
PAFETTMGYQAGELIGKELGEVPINEKKADLLDAINSCIKIGKEWQGVYCAKKKNGDNVQ
QNVKIIPVLGQGGKIRHYVSIIRVCTSNNKAEKISECVQSDTNTDSQTGKHKDRRKGSLD
VRAVASRSSEVSSQRRHSSMARIHSMTIEAPITKVISIINAAQESSPMPVTEALERVLEI
LRTTELYSPQFGAKDDDPHANDLVGALVSDGLRRLSGNEYVLSTKSIQQVSSSIITPISL
RDVPPRIARAMENEESWDFDIFELEAATHNRPLIYLGLKIFARFGICEFLNCSESALRSW
LQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPMDEAAALIAATIHDVDHP
GRTSSFLCNAGSELAILYNDIAVLESHHAALAFQLTMGDDKCNIFKNMERNDYRTLRQGI
IDMVLATEMTKHFEHVNKFVNSINKPLAALEESEETKKNQEAINSMLRTPENRTLIKRML
IKCADVSNPCRPLESCIEWAARISEEYFSQTDEEKQQDLPVVMPVFDRNTCSIPKSQISF
IDYFITDMFDAWDAFIELPDLMQHLDNNFKYWQGLDEMKLRGLRPPPE
>A0A8C6EKI3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcebus murinus|TrEMBL
FQRNRSFDVDNGTSVGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSM
SRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKA
TITG
>A0A2J7VI95|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Variovorax sp. B4|TrEMBL
MNLQILSDLHMDGAAWTAPLTEADAIVVAGDLFDDGARSAVWCVELAQTAGKPVFFVPGN
HDFYDGVISERLLNMHRIACAGDVYLLHNKSVELQGVRFVGTPLWSDFQIDGPASSVLAK
HAAQDLMGDFQYIRIGDGTGSARNLRLNDAVRMHERGLRALDRGLTNAYSEKVVVITHHA
PSVRSLTRGFRYSPLNGAYASDMDEYVGNSMAKLWVHGHMHATHDYMVGSTRVLCNPRGG
PRSLNVDFNPAMVVEV
>A0A1A8H6S4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothobranchius korthausae|TrEMBL
MLKRSRSAQGVTPSDENPDPLVGQFSSGCTLGVEACKVHRRFSGNLQLPPLSWRQAETER
DRGRPLTPEEDPVTRSRPTSLPIASLPRIDITQADSDSLEVENAPPLCCSPSDLQASPGS
GLVLHPNMANHGQRRESFLYRSDSDYELSPKSLSRNSSIVGELHSEDLIVTPFAQVLASL
RTVRNNFTTLTNVQCTSTKRSPAANQPCVTKVCLSDESYQKLAMETMEELDWCLDQLETI
QTYRSVSEMASNKFKRILNR
>A0A7G5DQV8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. MSPm1|TrEMBL
MPSLSTPSTNHSVLLVQLSDSHLFAEADGKLLGMDTRDSLQRVIERVLQEQPQIDLILAT
GDLSQDGSEASYQRFRQLISGIGAPSRWLAGNHDETPPMQSACKGSPLLEPVIDLGAWRI
VMLDSSIPGAVPGFLADNQLELLERALSEAPQRHHLICLHHHPVSIGCKWMEPIGLRNAD
VLFAILGRHPQARAVLWGHIHQEFDQMRGNLRLLASPSTCVQFTPGSEDFQVSNEAPGYR
WLRLHADGTLETGVSRVTGIHFEVDYSVKGY
>A0A829CNZ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli MP021552.8|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A182IU06|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles atroparvus|TrEMBL
MAELQDGLHRSPSGINGLLLFRRWIDNYNSDLSPDRRSSDDGMMLARRNGGASLKLRTSE
RSFAGKELQPASRATVQLTGPAAIASNRHWTDLNAQLTPRPFIIPCCVHVRARSLGGRRK
WNGFRDINASGTSSSSGRYGHRKSSLALTPEEEPLDSCPGTPPESYQERKISAGQYRPHP
TPHAIAPWITVTQPTDEGEETKDLLEFAERDEEQKGCHEEIVQITAGPELMAELIETLEL
RRSLPLGLSSCVESDDNGSERMAYNRTHSAPIIRPRTFGRRSNGLKVFRFPGIKEEPAFE
TAARLVSDLKFPNLLPPNPVIKILIAFCKNDPVFEALGNASHRLNLEPTFVKSAEAAIEA
FQSPNAGGHHIVIVDARYPRTIEAEALGRSIRNSKGSQHTTMVAVVKKSVFEKDDTAVIS
LLDVGYNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQALYTALHRSREAVIITDDT
LRAQYANRASERVLNMKMDEIVGRSLNDLVTADISNILSHTSRYKDYDGYLTTRRKSQES
SQIHVRAVPVSCIGRNPTHLVLILESSSSALVSSNAIGEALQTLPQGKEVPRGSLHSIRR
GSFDVRSIASDGLRRTSLAKLSSLPLEAPITKVLSLLAQVQENCSQDESKLLDRVMEFLK
REGLYSPQMKEIRTEDPVATDLIGALLTQGPTNILSSRRSSNDSIIRGGGRPSTGSIVFT
KTKESSLLSDLLQTALDWDFEIFKLEDLTEKRPLVCLGLELFRRFDVYNTFNCDEMTFKL
WLIEMEKYYHSENTYHNSTHAADVMQATAVYLQQLSNRELKIMDRMDEATALIAAATHDI
DHPGRSSAFLCNSDNMLALLYNDICVLESHHAATTFRLTLADDKINIFKHLDRDMYKLAR
SIIVDMILATEMTRHFEHLAKFVSVFGTDVESKDPLPPDNDDNQILVRRMLIKCADVSNP
TRPLKFCVEWARRIAEEYFMQTDEEKRKNLPIVMPMFDRTTCSISKSQIGFIEYIIHDMM
DAWNSFIEMPEIIRYMEFNYSQWKLFEEQGINTLSDIKRKQISLTEETASSISLEEKF
>A0A4P6M7E8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Blautia producta|TrEMBL
MAVCLLFLLTTGCIFYAFKIEPFRITTNTFAINEGGSGSESVKIIQISDIHIKEDYTYKN
LEKVVDRVNRQSPDFVVFTGDLYDNYAKYSDDSHIISALKKLHGEYGKIAIWGNRDYGGG
AVRKYQEIMELSGFTLLKNENMSITMENGKKILFTGLDDSLLGQPLMPDMAEAKAVDFKI
LLTHEPDSVQEFWDTGHPLILSGHSHGGQIRIPFLPVVNERAVAATSLSSRYSGGMYQVG
EKGTQKLYVNTGLGTTHISARFGVVPEITVFEIHL
>A0A727Z0K9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. houtenae serovar 48:g,z51:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A8C3FC43|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chrysemys picta bellii|TrEMBL
MLSEETYQQLAKETLEELDWCLDQLETIQTYRSVSEMASNKVRLPPSARTGVGRGGGWSL
CLSQHVSCPLRPSLPPSPRKPICLSIPPPPPSACPSLHP
>A0A5B8R6R1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella decolorationis|TrEMBL
MLKEAVSYSIADESVRIVQVTDPHLFADPEAQLLGVNTSKSLAAVLNTIRAVNYPAHLML
ATGDLSQDYSPESYRHFVTAVAPLNLPCHYLPGNHDDPRIMFLHMQGERVFGQQRILIGK
WQILMLDSTVRGKPGGHMGESQFELIEQAVAAHPEHHTLLVMHHNPILVNCAWLDQHCMD
NGTEFLRRVAQYPQIKALLWGHVHQQLDTHYDGPHGMLQLMATPSTCIQFKPQSPYFALD
VLQPGYRLLELKADGSISTNVYRVPGNLFSPDKDSSGY
>A0A8C8S6K1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pelusios castaneus|TrEMBL
MKQQPSCAGTGHLSMAGYGRMAPLELAVSPVKRLRTEYSFPYLFAEEAYQKLASETLEEL
DWCLDQLETLQTRHSVSEMASNKVGPIGLPGPLFLLLTCYRSWKFIQAGSRATPRKNFHS
FLNFFSMCTKWLS
>F0EUI9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus parainfluenzae ATCC 33392|TrEMBL
MNNRFEYEPASEVVKLLQITDPHLFKDTSKDLLGINTHESFSQVLKEIQLESFEYDVVLA
TGDLVQDSSDEGYLRFVEMVKPLNKWVFWLPGNHDFQPKMAEHLSQSPINASKHLLLGKH
WQVILLDSQVFGVPHGELSPYQLDWLKTKLAENPARHSLVVLHHHLLPTNSAWLDQHNLR
NAHEFSVVLAQFNNVKGILYGHIHQEVDGYWQGYQTMATPATCIQFKPDSNHFALDTLQP
GWREIELHPDGRIETRVKRIKQKIFLPNMEEEGY
>A0A7M7PZL1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nasonia vitripennis|TrEMBL
MSSVRGRFSFSNDDGDELQTSLRSLFNGHDPNYNDSSNSQDEKHYMGHRNSIEDVDLHQV
KGPSDVGCNWLTSSITSDNVKILLVFPRDDRQSEVLGLAAQRLGWQISEARDVEEALDLF
QTHSHDVVIIDRRGLHCQQADDICRALNNTHYNRTSVIIALVKRSIFVSSDQDEIATLQI
LDAGFNRALIECSSKEMLMNELIGIYANEVRPKLQLAAAHSLYLAVHRCRDMVHVTNDRH
LIQFANEVSEKLLGWKPDDLINKNLTELVTCENFTRMNQQLQKGREFHGNMNCKRKSNET
ITISSRIIPFCAYGRRPTHYIYIYDTTYLLENIDVTSALPNPVAHLHPRGSSHSLRSFDV
GSIGSDLQRRCSVAKIHNLPLEAPITKVITLLTTAMTEAVSPDVAMQIDKAIEILKTTEL
YAPYVREADELFNDPVTSDLIGALISAPQYSRDSRRSSNDSSGRVSQVQRILHQQTPASK
AAGKGIRAPREIEILLENCMDWDFDIFKLETMSGRRPLYYLGMNVMNHYSVPARLSCDER
TLQNWLTVIEVNYNAQNSYHNSTHAADVLQAIARFMRSERLKLLLDPLDEVAALIAAAAH
DIDHPGKSSQFLCNAGNKLAILYNDLSVLESHHAALTFRLTLSDDDVNIFKNLDRETYKM
IRQNIIDMILATEMTKHFEHLAKFVNVCSIRTEESQSEPFTDPVDSSVLLLPENVSLVKR
MMIKCADVSNPTRPLKFCIEWTKRIAEEYFRQTDEEKRRKLPVVMPMFDRSTCSIPKSQI
GFVDYIINDMMEAWDAFIDLPEMINYMKQNYETWKEYNERGISTLQDVETLQQSPELQIP
QSAQ
>A0A4R1K216|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Celerinatantimonas diazotrophica|TrEMBL
MEFEKIFTHVDSDGDLRLLQLTDTHLFANSAMGLLGVNTLASLEAVIAQIQQDDIPFDWV
MATGDISQDHSARSYERFVETVSVLEKPILWLPGNHDWQPVMHQTLSQKGLSRAKQLVSD
HWQLILLDTQVTEKPHGYLEPEQLDFLARSLSEYPQKHALILMHHQSCSIGCNWLDQHNL
KNADAFHEVIAPHPQVKAVLFGHIHQNFEYQSAQLAYIASPSTCIQFLPLSKEFALDRQQ
PGYRYLKLRANGEIHSRVRRLAGQQFLPDAQSQGY
>A0A4W5L1G5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hucho hucho|TrEMBL
DYCPVSVCLLTDESYQKLAMETMEELDWCLDQLETIQTYRSVSDMASNKVRLTRYVFNPL
SWTTGCHGSCIGSNNTLEGKRCVCVCVCVCVC
>A0A3Q0TAT9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Amphilophus citrinellus|TrEMBL
LPRCLSSPQFKRMLNRELSHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTIREREKPM
CHISGVKKLTHSSSLSNSALPRFGVKTEHEDALARELNDLNKWGLNIFRVAEFSNNRPLS
CIMYAIFQAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLHEENCDIFQNLTKRQRQSLRKLVIDMVLATDMSKHMSLLADLKTMVETKKVTS
SGVLMLDHYTDRIQVLRNMVHCADLSNPTKPLAVYRQWTERIMEEFFRQGDKERERGMEI
SPMCDKHTASVEKSQVGFIDYIVHPLWETWGDLVHPDAQEILDTLEDNRDWYQSTIPQSP
SPPPVDEDKDLNACIDKFQFELTLEETEQIFTRHLTPTCTAWLSSSPHTQQISPK
>A0A6M2BAA2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rahnella contaminans|TrEMBL
MESLFKLPLVNGAKVRILQITDTHLFAGEDETLLGVNTFNSYRAVLDAIKAQQREVDIIA
ATGDLAQDQSVEAYHQFARGISELAAPCVWLPGNHDFQPAMVNALQEAGISPSKHVLLGD
DWQIILLDTQVFGVPHGELSEYQLEWMERCLNAYPDRFTLLMLHHHPLPSGCTWLDQHSL
RNAHMLANVLVNYPKVNTLLCGHIHQELDLDWYGRRLYATPSTCVQFKPHCTNFTIDTVA
PGWRYLDLYPDGRVETQVFRLETSEFHPDTESDGYE
>A0A7G7RDF1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sediminis|TrEMBL
MPSLPAPSTESSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIERVQLEQPQIDLILAT
GDLSQDGSVASYQRFRQLTSAIAAPARWLAGNHDETPPMQAACKDSELLEPVIDLGAWRI
TLLDSSIPGAVPGFLADSQLELLERALSEAPQRHHLICLHHHPVSIGCKWMEPIGLRNAD
ALFAILDRYPQARAVLWGHIHQEFDQMRDNLRLLASPSTCVQFAPGSEEFQVGSDAPGYR
WLCLHADGRLDTGVSRVTGIDFEVDYSVKGY
>A0A349F9W8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp|TrEMBL
MKVTSSTTVKDTIKLLQITDTHLFEAEDGSLLSVCTNDSFKAVVDAVMQEDFPFEAILAT
GDISQDHSDTSYQKFAQGIQSLAQPCYWLPGNHDYKPSMNSVLPSEQIVQTEHVLLGENW
QMVLLDSQVEGVPHGRLSPQQLDLLDSKLRQYPDRHALVLLHHHPLLVGSAWLDQHTLKE
SEQFWQIVEQHSNVRAILCGHVHQDMQKQRSGATVIATPSTCVQFKPNSDDFALDTCSPG
WRELELHADGRFETRVKRLEEGVFVPNFDSNGY
>A0A498D7K7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter cumulans|TrEMBL
MPLINNNDQHKHDPVFDWTIIQISDTHLMDQHELDFVSVNPEQSFHDVMYHIQQQVPHID
AIVHTGDLAQVPVAETYSRYLQFMNGLDIPHYQIPGNHDCTDIFPFHLQQDQAHILHYGA
WSLILLNSAVKDKVDGWISEVQLQQLHQLLSDHPQQHILIACHHHPFAMESAWIDQHKLK
NATHLMDVISQHSNVKIVICGHVHQDSMNTWNNIQFLSTPSTSIQFKPHSQTFALDQVLP
GYRVIRLKNNGEFETEVHRVALSQPQINVEISGY
>A0A4R1FX84|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Volucribacter psittacicida|TrEMBL
MENLFSLDTAAGSVIRLLQITDPHLFADTNSELLGINTFASFQQVLAEIKQRNFAYDLIL
ATGDLVQDNSEQGYLHFCQSIKQLDKICFWIPGNHDLQPKMRELLNQSHGNIHPAKHILL
GDQWQILLLDSQVFGVPHGELSQYQLDWLQHTLTAYPERYSLIVLHHHLLSTNSAWLDQH
NLRNSQHLADILAPFKQIKGILHGHIHQQVDSQWQGYPVMATPSTCIQFKPDCNQFTLDT
LQPGWRELTLHPDGTITSQVHRIQQAQFLPNMQEEGY
>A0A7S8XGI2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter johnsonii|TrEMBL
MTLNNEKNWTIIQISDTHLMDQDHLEFVRMNPEQSFHHVMQHIVERHPQLNAIVHTGDLA
QVPVPRTYQRYLEFMQSLKTPFYQVPGNHDNAEHFPFHQQQNKVHVIHFGPWSVVLLNSA
VKGKIDGWVDETQLNQLEQILQEFAQQHIVIACHHHPFEMQSKWIDQHKLKNTQDLTAVL
AKYHNVKIVLSGHVHQESWREWHGIQFYSTPSTSVQFKPLSDHFALDEQAPGYRILQLNA
DGSHETHVERVLHAQQKINVEISGY
>R0JTJ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anas platyrhynchos|TrEMBL
MSLPSNCEHLTLKKVSRFRSAYIHGSPYAINKPIDIKQQKRRFDVDNGTSSGRSPLDPMT
SPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIVGTITGYTGKVLVC
PVGKCSPFVLWDEISAGLPNAVTCPESCAETGWFISRPIDTQKIPDLCQGQLGIPVGIDR
HASAIGAGVVALSYCNTFSQWIAANSVSPVQKFRLKPFCMFQVLASLRTVRNNFAALTNL
QDRAPSKRSPMCNQPSINKATITAHWLMNIENKTVTMWIDRWVYCECIFISAFDSCDQ
>X2JMZ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aggregatibacter actinomycetemcomitans HK1651|TrEMBL
MFRVIQITDPHLFKDATGELLGVNTQESFSQVLSEIRQQPYDYDLVLATGDLVQDSSEEG
YLRFCESVKPLEKTVFWIPGNHDFQPKMFDILKRDNICDKKHILLGENWQILLLDSQIAG
VPHGQLGQYQLDWLMAKLKEHPQRYSLVVLHHHILSTHSAWLDQHNLRNAHELAYTLAPF
NNVKGILYGHIHQQVDGEWNGYKIMATPSTGIQFKPDSNTFALDTAQPGWREIELYADGR
IETRVKRIQHKTFLPNLQEEGY
>A0A8D5G628|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio alfacsensis|TrEMBL
MQSSSDSIKLLQITDTHLFAADEGSLLSVRTADSFYAVVQEILKRQVQFEYIFATGDISQ
DHSAESYQRFADGIAPLGKDCFWLPGNHDYKPNMSSVLPSSQIQTVEHLYLGDHWQVILL
DSQVVGVPHGRLSDQQLSLLEEKLAENANRHTLVLLHHHPLLVGSAWLDQHTLKDADAFW
QVVDRFDNVKGIVCGHVHQDMNVVHHGIRVMATPSTCVQFKPNSDDFGLDTLSPGWREIE
LHQSGDITTQVNRLSEGQFQPDFTSNGY
>A0A7K0DH13|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nocardia aurantia|TrEMBL
MHITRVAEYPQPDHVLFHFSDTHFIAGDGELYGAVDSERRLRRLLERALASRITPTAIVF
TGDLTDRGEARAYDKLRALVEPFATAVDAPVVWLNGNHDDRATFREHLLDEERSAEPLDR
VYQFDGLRIVTLDTTIPGEHHGEISAAQLAWLRSVLDEPAPFGTILAMHHPPIPYIQDLA
VTVELRDQRALADVLDGTDVRSILSGHLHFSTTGTFAGIPVSVASSACYTQDLAVEVGGQ
RGRDGAQGFNYVHIYPDTVMHSVVPIDEGPTVGRPATAAQTTERLAEAGIVIPPASGIPH
VVQRRTGAREADGETVA
>A0A8B3K7J7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter mori|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLNAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLLESGISPAKCVFAGD
HWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPARNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLVNFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGNLTTEVCRLSGAKFRPDTASEGY
>A0A3D8UMI5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kangiella sp. HD9-110m-PIT-SAG07|TrEMBL
MNILHLSDPHLFADDSSTLLGVNTNDSLQAVLEDIRRRKINPDLFVVTGDISQDYTPESY
QKFVEYLAPFNKPVLSLAGNHDERPKLKKYLSTAPFSTAEQLITENWQLLMLNSHVPGRV
YGNLSEEELLWLEKCLSENQDLPTIVFTHHHPIPVGSHWLDQIGIDNGQQLVKILSKHPQ
AKMCAFGHVHQSTDRTHQDVSYCSVPSTCVQFKKHSADFSASQEKPGYNLYSCSKDGTII
VDNFRVDNYLPSVNLAISGY
>A0A6B0VEM7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ixodes ricinus|TrEMBL
MGCTQSGIQRRSRSHDDRSQGPATPVVCDVAPPTANATTMTAPGSLTTTAAPKGGCGAGV
LRGNAHRFENNFPKVRQKVVTCDGVNDCAVPLCSIPEDGRKGTVALKFGSMYLTVPSVRV
LFVFVKEDAQYNALKWASEKMHYEYRLACSMDEAVESYLNVQPHLVFIDARSKTCVDPIA
LCRTLRGFRGSQFSCIVAVVKKGLAEKEEAAIIPLLKSGFNRWFTETCSFGVCLNEMIQI
EHNDLINLWKLRASEALFSALHIARDGVIITGSGHEIQFMNRAAEKLVGYSVEEMLGVNA
QELHRTDSLKTDVVQTISTQLKKGKEWEGTLFHKRKSGECIPMWSKIAPVEIHTGISDHL
VYIKECPFFMEKPFSPDADCLPYQLNTSLKSSRKASCDVRSLCSEVGMNRRQSFAKFHAM
TIEAPITKVINMLVATQENSPVFVVQALDRVLEILRSTELYNPQLGVGQGKSEDQMTSDL
VSGLITTGQKPTGVRRLSHETGVVKVNVTTPSTTLPSLSTAPSKIKDLLENDVKWEFDII
ELETLSGRRPLIWLGLSLFSKLNVHTSLDCDDATIRNWLQLVESHYLENPYHNSTHAGDV
MQATAYFLLKLRKKDIFDPLDEAICLISAVVHDIDHPGKSSPFLCNSDNELAILYNDRSV
LESHHAAFAFKLTLSDEKVNIFQNLEREVYRTVRLSVIDMVLATEMTKHFEHLSKFLNAF
QKPIQEDEAFESEAMPDHGDSGLRSAENIILIKRMLIKCSDVSNPARPIQLCSQWASRIA
EEYCAQTDEEKRRGLPVVMPAFDRATCSIANSQTGFINYFVRDMFRAWSDFGEFPELMEY
IEKNYIYWKDKEPQSNK
>A0A3B7MDY3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Thermosynechococcus elongatus PKUAC-SCTE542|TrEMBL
MKQPIRLIQLSDLHLFATAAGRLLGLPTAQSLAAVLETIRNHFPVDALLLTGDLAQEPIA
ATYERLATAFADFTCPVYWIAGNHDEPKAMLPALERPPLKCDRQINLGAWQGLLLSSQAD
GKVHGELSPETLSWLEDTLSRSGDRPTFIALHHPPFETGAPWLDSSRLQNPEHLFAVLDR
HPQVKLVLFGHIHQEFVTERQGVTYLGCPSTCIQFLPRAPEFSLEPIGPGFRHLSLYPDG
TFSTHIERVEIPLTLDFSAKGY
>A0A455VKR1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia symbiotica|TrEMBL
MESLFKLPVASGNTARILQITDTHLFADKHETLLGINTYRSYHAVLDAIQAQRRELDLIA
ATGDLAQDHSLSAYQHFAEGIFQLPAPCVWLPGNHDYQPAMVDALTTAGIAPSKQVLLGD
SWQVILLDSQVYGVPHGELSEYQLEWMARCLQTHPERYTLLLLHHHPMPCGCTWLDQHSL
RNPHMLATTLLRYPKVTTLVCGHIHQDLDLEWQGRCLLTTPSTCVQFKPHSTHFTIDDVS
PGWRYLDLLPDGRVETQVYRLENNDFRPDMDSDGY
>A0A7W4DD93|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas guryensis|TrEMBL
MSRPVSPAHDPSVLIVQLSDSHLFAEEDGKLLGMNTCDSLQRVIERALEEQPRIDLMLAS
GDLSQDGSLASYQRFRELTDPVAAKARWFAGNHDELPSMRAACKDSDRLEPILDLGNWRI
TLLDSSIPGAVPGFLGDDQLELLEQSLNSAPERHHLVCFHHHPVSIGCNWMEPIGLRNPD
ALFAVLAKAPQVKAILWGHIHQEFDQQRDGVRLLASPSTCVQFAPGSEEFQVDTTAPGYR
WLRLHADGRLETGVSRVTGIHFEVDYSVKGY
>A0A8G0SEK9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. S11A 273|TrEMBL
MPQQSIPANDAPVYVVQLTDSHLFADAQGTLLGMNTRDSLQRVIDTVREEQPRVDVLLAT
GDLSQDGSEESYACFRELTASLRAPARWLAGNHDEPLPMEKAAQGTDLLNPVLDIGNWRI
LMLNSAVPGSVPGVLDEGQLALLEQSLSDAPERHHLICFHHQPVSIDCAWMAPIGLRNAE
ALFAVLDGYPQVRALLWGHIHQEWDQQRNAVRLLASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLHAEGSIDTGVSRVSDFAFTIDYAGDGY
>A0A3R9F0T7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Atlantibacter subterranea|TrEMBL
MESLLNLPVADGASVRILQITDTHLFAQKSETLLGVNTWSSYQAVLEAITAQQRPCDLIV
ATGDLAQDHTPEAYQHFAQGIAAFSAPCVWLPGNHDFQPAMFSALQDAGISPAKQVLCGE
KWQILLLDSQVFGVPHGELSEYQLEWLEAKLAENADRFTLLLLHHHPLPAGCSWLDQHSL
RNAGELDAVLGRFPNVRHLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTQVERLEGTQFNPDTASEGY
>A0A1X3LSV9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli TA249|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A8D4QII0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIKQENNQFDVILA
TGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNVAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLGKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELYSDGSIRTEVKRIQQAEFLPNMQEDGY
>A0A5U1F5V7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFCAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A1V3IRE7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rodentibacter rarus|TrEMBL
MKNTFVYQTENPIVKLLQITDPHLFKDEKNELLGINTQASFAQVLKEIQQENREFDVILA
TGDLVQDSSDEGYQRFVKMVKPFGLPVFWIPGNHDFQPKMVENLNQPPMERAKHIVLGAH
WQVLLLDSQVYGVPHGELSQYQLDLLKTTLKKYPEHHTIIVFHHHVLPTNSAWLDQHNLR
NSHDLFDVLSSFKNVKGILYGHIHQQVDSFWQGYQVMATPSTCIQFKADSQHFALDEAQP
GWREIELHSDGTIVTTVKRIRQTVFLPNMQEEGY
>A0A419N835|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rahnella woolbedingensis|TrEMBL
MESLFTLPLVNGAKVRILQITDTHLFAGEDETLLGVNTFNSYRAVLDAIKAQQREVDIIA
ATGDLAQDQSLEAYHQFARGICELTAPCVWLPGNHDFQPAMVDALRDAGINPSKHVLLGQ
HWQVVLLDTQVFGVPHGELSEYQLEWLERCLKGYPDRFTLLMLHHHPLPSGCTWLDQHSL
RNAHMLANTLVNYPKVNTLLCGHIHQELDLDWYGRRLYATPSTCVQFKPHCTNFTIDTVA
PGWRYLDLYPDGRVETEVFRLATSEFHPDTESDGYE
>A0A1X1BWH4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea conspicua|TrEMBL
MDSLLTLPAANGSAIRILQITDTHLFAGKHESLLGVNTWSSYEAVLDAIIAQHRDYDLII
ATGDLAQDHSVEAYQHFAEGISRLPRPCVWLPGNHDFQPAMVDTFADAHINSHKQILIGE
QWQIVLLDSQVFGVPHGMLSDYQLEWLEKALARYPQRHTLVLLHHHPLASGCTWLDQHSL
RNSHQLDAVLQHYPLAKTLVCGHIHQELDMEWHGRRVLATPSTCVQFKPHCTSFAIDTVA
PGWRWFTLHPDGQLETEVNRLDTDIFRPDLDSDGY
>A0A8C6GVX4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus spicilegus|TrEMBL
MNKAAAIVLSGDMKGTCSQKRGTQLKKSQRGSILVASFDVENGPSPCRSPLDPQAGSSSG
LVLHAAFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLR
SVRNNFTLLTNLHGAPNKRSPAASQAPVSRVSLQVERNDV
>A0A6J1MK25|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila hydei|TrEMBL
MSLNVSKCCTGTSGTSSSGGGRPGHRKSSLALALTPEDDSMDVYQRNLMDLKYPTVLPPN
PQLKALLVFHKSDSICEVVTLACQRHQLDVTLVKSKEEALETLHKSYATAQCYHLIIIDA
RSTKGLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDALIALLDAGVNRCIAETTNLT
LCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLNMR
LDEIISKPLGDIFVSDLSTISEQGKSIKEFDGILMVRRKNQESIPMHVRVVPVACIGSAP
THLIFNFDIPGGGMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSL
PLEAPITKIINLLSQVQENCSADEARLIDKVLDFLKREGLYSPQMKEIRTDDPIATDLIG
ALLTGPSVYSSRRSSNDSIIRTGNSTRTATIVPAKMKANPIIMELLEESLKWDFDIFKLE
EITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADVMQ
ATGAFITQLASKDMVMDRMDEATALIAAAAHDVDHPGRSSAFLCNSNNPLAILYNDLTVL
ESHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFG
NEMEPRELVQSEEETSILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYFMQTDEEKQR
HMPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWDGFIDMPELITCMQINYSQWKKYDE
QGVNTLADIMAKQPPVGNKSSSSK
>A0A4Q9UXW0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Azotobacter chroococcum subsp. isscasi|TrEMBL
MPSPSSSVADSLLLVQLTDSHLFADAGARLLGMQTEDSLQRVIELVRREQPRIDLLVASG
DISQDGSDESYARFRQRCAPLAAPLRWIPGNHDAREALNRASAGGDCRQPVVDLGNWRIV
LLDSALPEAVPGFLEPGELALLERALAEAPERHHLVCLHHHPVSIGCHWMESIGLRNAEA
LFAVLDRFPQVRALLWGHVHQEFDRMRRGVRLLASPSTCVQFTPGSEDFSVSDQAPGYRW
LRLHADGRLETGVSRLTGYRFQIDYGKGGY
>A0A2M9H4X4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter ruhlandii|TrEMBL
MTRILQFSDTHFGTERKPVVEAALDLARALAPDLVVISGDITQRARRGQFAAARKFIERL
SLPVLAVPGNHDIPLFNVFARALNPYGNYKRALGAVLEPVYETAGLLAIGVNTTRPRRRK
DGEISDAQIARVAQRLRQARPGQLRVVVAHHPVRAKVESDRFNLLIGRERALAAWAQAGV
DLILGGHIHLPYVLPASADPAVAAGWAVQAGTTCSRRVRGNIPNSVNVITREGEGDTRVC
HVERWDYAAAAHAFAPVDKTLVAG
>A0A6I7DAC1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteus columbae|TrEMBL
MESQLELSVKHKNTVRILQITDTHLFANVEDTLLGINTYRSYHAVLNTIREQGLDVDLIV
ATGDLVQDQTFEAYQHFADGIATLTPPCVWLPGNHDYQPAMIDALNQAGILSAKQVLIGD
NWQMLLLDSQIQGVPHGELSDCQLDWLTRCLESQKHRDTIILLHHHPMPSGCTWLDQHSL
RNSQELAERLRNHSQVKMMLCGHIHQEMDEMWNGIRLLATPSTCIQFRPHCTNFTLDTVS
PGWRYLEMSLSSDEKGKIETQVYRLAGTEFCPDLDADGY
>A0A653AX24|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clostridium neonatale|TrEMBL
MLSAGDQIQSRDKKNASKTYDKNEIEYAGYLSPSLLKSLPVATAIGNHDAPSGNYSFHFN
NPNASELGSTMAGGDYYYSYGDALFIMLNTNNLNIAEHKKLIEKAISENKDAKWRIVTLH
QDIYGSGEHSNEPEIVNLRYSLIPILEDNNVDVVLTGHDHTYSRSFILKGGSKNESKLIT
EDEFDAYIDGETPIDSKYNEYLTSIEDPSAVTNKSINVTNPDGILYMTANSGSGSKYYDL
VQTQQSYIAARWQEDVPTYSIVDITDNTFTINTYRTDNGEKIDDTFTITKTK
>K7EKV1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|TrEMBL
MPLVDFFCETCSKPWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISTTFLGSVHGPG
DSRRPLRGCHPRCGSPWGLQPVPHQHQFGAGAHVQR
>A1YMU2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sus scrofa|TrEMBL
LSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTN
SSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFK
IPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFA
SAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQ
RQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHC
ADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDK
>A0A3G8JMV0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gordonia insulae|TrEMBL
MFVVAHISDLHFNGTRYNRRRIESTLGYINARADGIDALLVTGDITDEGSESEYREAHGV
LYSPLPMLITAGNHDHRERFNAGLLGRETSEPVNQAEVIGGVLFVVCDSSIPGENDGYLT
DETLAWISATITAEGAATPVLIAFHHPPTTLGMPFMDSIRQTGEARLAALVDRHPNIVAF
LCGHAHTPSVTTFAGRPLAVAPGAASTLNLPFEGTEIVNRGQPPGIAFHFLDGVGGPPDG
WRLVTHFRSVMF
>A0A0S7GXQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
MIVTPFAQVLASLRTVRSNFALITGQQDRAASKTRSSGSNPPSMCKTSLAEEPHQQLAIE
TLDELDWCLDQLDTLKTRNSVSEMASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLE
KPDDMDIMSPTTKEKDKKKHPMSQISGVKKATHSLVPSTIPRFGVNVSQEEFLAKELEDI
DRWGLDIFKVAEYSGKRPLTVTMYTIFQERDLLKTFKIPADHFINFTMTLEDHYRSDVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLENHHLAVGFKLLQEDNCDILQNLSKKQRQSL
RKMVIDMVTPTSQPAQFREFRLSGVF
>A0A0S7HF31|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
SAAMDPLGPDYVSVCLLADESYQKLAMETMEELDWCLDQLETIQTHRSVSDMASNKFKRM
LNRELNHLSEMSRSGNQVSEYISNTFLDKQNELELPCPVQKVRKRKQNQQQQQQQVGMMT
QISGVKKVNHTSSILGNVGNRFGVKTDQEELLSKDLEDINKWGLNIFKVTEHSHNRPLTC
VMYKIFQVSFCLLLEG
>A0A0S7HFP5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
SAAMDPLGPDYVSVCLLADESYQKLAMETMEELDWCLDQLETIQTHRSVSDMASNKFKRM
LNRELNHLSEMSRSGNQVSEYISNTFLDKQNELELPCPVQKVRKRKQNQQQQQQQVGMMT
QISGVKKVNHTSSILGNVGNRFGVKTDQEELLSKDLEDINKWGLNIFKVTEHSHNRPLTC
VMYKIFQERDLMRTFKIPPDTFVTFMLTLEDHYHSDVAYHNSLHAADVAQSTHILLSTPA
LDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKL
LQEDNCDIFQNLSKKQKQTLRRMVIDMVLATDMSKHMNLLANLKTMVETKKVTSSGVLLL
DNYTDRMQVLCNMVHCADLSNPTKPLDLYRQWTDRIMDEFFHQGDREREKGMEISPM
>A0A7L6YF75|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. RHB21-C01|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLKAIHAEGQEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVMIGE
HWQILLLDSQVFGVPHGELSEFQLEWLEQKLAEAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSVLVNFPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIG
PGWRTLELFADGSLHTDVCRLEGTEFRPDTASEGY
>A0A0S7HFL2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
SAAMDPLGPDYVSVCLLADESYQKLAMETMEELDWCLDQLETIQTHRSVSEMASNKFKRM
LNRELSHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTLREREKPMCHISGVKKLTHSS
SLSNATMPRFGVKTEHEEALARELDDLNKWGLNIFRVAEFSNNRPLSCIMFAIFQERDLL
KTFRIPVDTFVTYVMTLEDHYHANVAYHNSLHAADVTQSTHVLLSTPALDAVFTDLEILA
ALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLHEENCDIFQNL
>A0A0J8YS18|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacteria symbiont BFo1 of Frankliniella occidentalis|TrEMBL
MDSLLKLPVASGSRVRILQITDTHLFAGKHETLLGVNTWASYDAVLEAIAAGQRHYDLIV
ATGDLAQDHSVEAYQHFAEGIARLPAPCVWLPGNHDFQPAMFSTLAESSIADEKQVLVGD
RWQIVLLDSQVFGVPHGELSDYQLEWLERALAAEPQRHTLVLLHHHPLPSGCSWLDQHSL
RNPHMLDAVLQRYPLAKTLLCGHIHQELDLDWHGRRVLASPSTCVQFKPHCTNFTIDAEA
PGWRWLDLYDDGRLETEVQRLATRKFNPDLDSEGY
>A0A379DSY1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pragia fontium|TrEMBL
MESLFQLPLARGSRVRVLQITDTHLFAGMDETLLGVNTLQSYQAVLEAIAEQGHDYQLIV
ATGDLAQDRSLAAYQRFAAGIAHLPAPCVWLPGNHDFQPAMVDAMAAAEILPSKQVLLGD
DWYLILLDSQVLGVPHGELSEYQLNWLDHSLSRYADRHALILLHHHPLASGCTWLDQHSL
RNAHMLAEVLDKHPQAKTLLCGHIHQDLDLDWNGRRVLASPSTCVQFKPHCTNFTIDELA
PGWRYLDLYSDGSIDTTVCRLNSDAFRPDMNSDGY
>A0A209B126|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia frederiksenii|TrEMBL
MESLFKLPMASGAKVRILQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGISRLSAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLVGD
NWQILLLDSQVFGVPYGELSDYQLEWMERCLVAHPERYTLVLLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGILETEVRRLASDEFCPDMDSDGY
>A0A8B9MSS4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Accipiter nisus|TrEMBL
MLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEIEIPSPTQKEKEKKKRPMSQISGVKKL
MHSSSLTNSSIPRFGVKTDQEDVLAKELEDVDKWGLQVFRVAELSGNRPLTVIMHAIFQE
WDLLKTFKIPVDTLITYLMTLEDHYHSDVAYHNNIHAADVVQSTHVLLSTPALEAVFTDL
EILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDI
FQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQ
VLQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFHQGDWERERGMEISPMCDKHNASVEKS
QVIDLSRHLNKTV
>A0A6N7C8B8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rhodococcus sp. T7|TrEMBL
MVDRAAPNIVLSQGPSPKVPLVSDMNRRKFLTFAGLGAIGTVGFGARPWGLQYAGAAPLP
TSGAGTTLEAVAVPLGSSGYRRLGAGPGWPTIVRTELAEARSGREDRRTALASLVQLTDV
HLVDAQSPMRFEYVHPLTGSAFRPHETLTAQGLVTLVARVNALASGPHTRRAFDAVVSTG
DNTDNKEFAELGWFLTALNGGTIVPNTGAPDRYEGVQNSGADLYWNPESSIQDMYKKAGF
PEIPGLLGAAIAPVTSPGLNTPWYCVFGNHDDSVEGTVPSGIPPLEAMYTGSLKFEVPGS
PEQAKAVDIATKFDPGAIPAALSAFTTPPRVVTPDPARAPFTPRQFIAAHLDPANTGPGP
AGHGFAPDAGETGIGYYSFEIAPGVVGISMDSTNRAGFVDGSLGAAQFRWIEDTLAAGSS
RYYDTSGNPVSQARSDTWFVLFSHHTSGSMDNVVPDPSAPAEPRIRGSRLVDLLHRFPNV
LAWVNGHTHENRITPWPGSTPEQSFWEINTASHIDFPQHGRIIEVVDNVDGTVSLLTTLF
EADSPYAVDHTDLSPLGLASLYRELSFNDIHADPDLGGGTADRNVELVLASGR
>A0A368LQ04|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio casei|TrEMBL
MIEPNLDDVTLVQITDTHLFSDSEGELLGVNTLNSFSAVVNDVLESGLEYHAIIMTGDVS
QDHTDVSYSRFEHGILPLKQDCYWLPGNHDYKPSMHSIYPSTQIKDDTYLQIGKHWQVIL
LDSQVEGSPHGFLSEQQLEYLDSVLKQHPDRFSLVLLHHHPVLVGSQWLDKHCLHNSNDF
WGVIKPHQNVKGILCGHVHQDFHQVHLGVSVVTSPSTCIQFKPNSDDFALEKVSPGWRAL
TLKANGVIDTQVYRLADEAFLPDFDAQGY
>A0A3Q9IZC4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microbacterium lemovicicum|TrEMBL
MRIAEYPAPERILLHLSDTHLRAPGPMLFDSIDGARRLARALGAIEASRVRPDAIVFTGD
LVDLGETDAYGTLRALVEPFAERLGAPVFWVMGNHDDRASFRAELWGQHPADPSAPVDRV
DELDGLRLVTLDSTVPGHHHGEIGDDQLAWLADVLATPAPLGTILAMHHPPVPAVLPLAA
SVELRDQQRLARVLRGTDVRAIIAGHLHYSTFATFAGIPVSVASSTCYAQDLTVPTGGTR
PQDGAHSFNLVHVYDETVVHSVVAVDAAPALEHIDADEAQRRLRLAGIETPLSDARRISP
PTEPLTVLR
>A0A6G7VGB0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Caldichromatium japonicum|TrEMBL
MPIRLIQLSDTHLFADPGGQLLGITTRRSFEAVLDQVMALAPDALILTGDLVHDESAVAY
RYLNEALAKIGLPCACIPGNHDLPELMMAHLAYAPSGPVALRRLGGWNLILLDSRIQGED
GGHLHAEQFAQLDALLSAEDAPALIALHHHPVAVGSPWLDGIGVADGATLLALCERRPQI
KAILFGHIHQAFAAQHGDCLLLGTPSTCLQFKPASAEFALDAARPGWRELSLYPDGHLET
RVMFLDDYAEQPLRKAEGY
>A0A377ADU5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITETHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>U2NFL6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia fonticola AU-P3(3)|TrEMBL
MESLFRLPVASGAKVRILQITDTHLFAGKSETLLGINTYASYHAVLDAVIAQQRECDLIV
ATGDLAQDHSQAAYRHFADGITRLPAPCVWLPGNHDFQPAMVDALAAAGISPSKQVLLGD
NWQVLLLDSQVFGVPHGELSEYQLEWMERCLEAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHTLAAVLWRYPKVNTLLCGHIHQELDLVWHGRRLLATPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A5R1M2Q8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIANFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7X5QE61|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus cinerea|TrEMBL
MESLFELPVVEGTTAKILQITDTHLFAGKEDTLLGINTYRSYHSVLDAILAQDTDIDLIV
ATGDLAQDQTLKAYQHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGISPSKQILAGK
YWQLLMLDSQVQGVPHGELSEYQLEWMKKCLDEYPERYTVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLRGYSRVKAMLCGHIHQELDIDWNSIRMMATPSTCVQFKPHCTNFMLDTVA
PGWRYLELSVNDKGEFGLTTQVYRLESNEFCPDLESDGY
>A0A6D0EJB8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLNLTVAGGAPVRVLQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEKREYDLIV
ATGDLAQDQTAAAYQRFAEGIASFSVPCVWLPGNHDFQPAMYSALQDAGISPAKRVFVGD
HWQILLLDSQVFGV
>A0A8C6ETK1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marmota marmota marmota|TrEMBL
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQ
KDREKKKKQQLMTQISGVKKLTHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIF
NVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAAD
VAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDES
VLENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMV
ETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKE
RERGMEISPMCDKHTASVEKSQVFKRRNFLVIVELESSISFFIL
>A0A2S5CIB4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylovulum psychrotolerans|TrEMBL
MAHEKNYTLRILHISDLHERGPRETESWRRQRVLGATWEHNLEAVTAAGPIDLVCFTGDA
ADWGKPGEYAAATAFFHAVLKKLSLPPERFFLVPGNHDIDRGLHLAEWQKLRETFSQMDG
LTLSRWLRGSGKPPPGADTGWLEPVLARQAAYRQWLTELGREALLPERHDHGRVGYHVCP
DFPGLPFPIHITGLDTAWLAGDDHDAQKLWLTDDQIMLHATDKEGNKFPGLRLVLCHHPL
WDLADHAAAKNLLAEHADLLLRGHLHNAVLERSDDPDRGLVELAAGCLYEGHHADHYPNG
CQLITLQLDGQGRPISVEPWFRAWSERGHWHDDDSRYKQSHQGRLLWPLAQAIARIDPSS
NPYDFNRPALPPNFVGRVALMDSLIQALEEGSSVSLVGDRCIGKMSVLKNFEQKARIMAR
TVVLLRGEGPEAASLSAFVAAITGKACADCADPAADRLAAWVDRVGLPGLPPVLLLDEAE
IFLRKFEYRFFERLRGLLDRLCLVLATHQPIDLVFEQLGRGSPFDNKLRIEWLGLLEPAA
AEQLVRRGEGKLDGEDQALMRRWAGRHPYFLQLLGYRLAEARRHGKSREWAVDQARSNAY
PRLRQLWKTLRNKDKQALRNVATGGFSATNSTFRLRGLQDENGRLFGEVLRQWLEEEDEA
>A0A1T0AXT9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|[Haemophilus] felis|TrEMBL
MFSTYHYDTDAEVFKFIQITDPHLFKDEKEELLGVNTLQSLQQVVSEIQQQDFDYDIVLA
TGDIVQESSDESYQHFCRAVAPLKKPVFWIPGNHDFQPKMFDILNQETQNICSKKHILVG
KNWHILLLDSQVFGVPHGLLSAYQMDWLVAKLKDHSERYALIVLHHHILPTNSAWLDQHN
LRNAHELANALSPFTNKVKGILHGHIHQQVDSYWHGYKIMSTPSTCIQFKPDNNTFCLDS
LQPGWREVCLHSDGRIETQVKRIQHKQFLPNMNEEGY
>E9IKR3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Solenopsis invicta|TrEMBL
KNVEMSPRARRRAKIYKLLESMYLDKEEPKGPQDLSNYLLTTNVPSIVKILLVFSKDDQQ
MDILANSARRLGWSVSVAKDAEKAIELFQNRAHELVIIDHRGHHAAEGDAICRAIRSSPV
YHSSVIIALVKKSYFMLDEKDHIVALNLLETGFSRALIECSHEGILINELVGIYTSSLLP
KTQLAAAHALYLALDRCRDMVHVTNDKNIVQFLNKVSEKLLGYKTEEMIGRNLSEIVYYE
NFALMEQQLSKGREFEGNMNCKRKNNQMITINCRIIPFCITLKKPSHYIYVYDTTYLSEN
SAPISPICSPLHPPLKTSTLSNARKSSDVRSGVSEGRRRSSLQKLHTLQLEAPITKVITL
LSNAVTDTTNPETAAQIDKAIDILKTTELYVPHLKEDKAMYSDPVATDLVGALLASPRTA
WESRRSSSDSARLSTIKAITGPASTRVQVKNFRGPQEISEILDKSLDWDFEIFKLEVLTE
KRPLVFLGLTIMNLYQVPTTLHCDERTLQNWLAIVEHNYNAENSYHNSTHAADVMQATAR
FMQSKRLKEILEPLDEVAALIAAAAHDIDHPGRSSQFLCNANSRLAILYNDLSVLESHHA
ALTFKLSLSDDSVNIFKNLERDAYKLLRQNVIDMILATEMTKHFEHLAKFMNVCSARIGD
GQETYSDSLDMSVLLQPDNIILVKRMMIKCADVSNPTRPLRSCIEWARRIAEEYFNQTDE
EKKLKMPVVMPMFDRMTCSIPKSQIGFVDYIINDMIEAWDVFIDMPEIVGYMRHNYEKWK
EYNEQGISTLQDVEKLQQHPEIQIP
>A0A7T0JS75|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylomonas sp. LL1|TrEMBL
MLKVLQITDMHLLPHSGDIMLGIDTEHYFKLTLEHAHAVHGRFDLILLTGDLAQDPCPGS
YQRLYRHLNGYDTPCLCLPGNHDDLSLMTKYLNNGLVSCQKHLVLGNWLIIGLNSQKPNS
PVGALSREELVFLQRTLQSNSDRPTLIAVHHHCFASGSAWLDTMQIQNSEAFLKLIEGFG
QVKAVTCGHIHQEFACQEKPIAFFATPASCFQFTPNSSEFSIDETAPGYRIFNLYDDGGL
QSDCHRLPVKLDNLNRNAHEY
>A0A5N9IDV7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. MN1F|TrEMBL
MPHPDPSPAPVHVVQLTDAHLFADPAGTLLGLNTRDSLRHVVAQVGREQPRVDLLLCTGD
LSQDGSVASYEAFRQVTREMPVLTRWLPGNHDEAKVMVEVAPELVQSVTDIGSWRVVMLN
TAVPGATHGLLERDQLSALDDALASAGARHCLVCCHHQPVDIGCAWIAPIGLRNADELLQ
RLRGYPQVKALLWGHIHQEWDELRAGLRLLATPSTCIQFAAGSEDFKVSDEQPGYRWLRL
HADGQLETGVERAADFEVTLDFNSAGY
>A0A502LUU3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus haemolyticus|TrEMBL
MKNTFVYQTEKSTIKLLQITDPHLFKEKETALLGVNTQASFTQVLKEIQQENNTFDIVLA
TGDLVQDGSDEGYRRFVEMVTPLNKPIFWIPGNHDFQPKMVEHLNKTPMESAKHLLLGKY
WQVLLLDSQVYGVPHGQLSQHQLNLLEEKLAQHPNRYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLGKFSNVKGILYGHIHQEVNAIWNGYQVMATPATSIQFKPDSHHFTLDNLQP
GWREIELHENGSIYTQVKRIQEAQFLPNMQEEGY
>A0A151MQB9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alligator mississippiensis|TrEMBL
MPDAGPRLPASWSCTKFKRMLNRELTHLSETSRSGNQVSEYISSTFLDNQHEVEIPSPPP
KEDKEKAQRPMSQISGVKKLMHSSSLSSASIPRFGVKTDQEGPLAKELEDANKWGLDMFK
VAEYSGNRPLTVIMYTIFQERDLMKTFRIPPDTFITYMMTLEDHYHADVAYHNNIHAADV
AQSTHVLLSTPALEAVFTDLEIMAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDASV
LENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMAIDMVLATDMSKHMNLLADLKTMVE
TKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFHQGDRER
EKGMEISPMCDKHTASVEKSQVCAGPLLPAGSTGGWSRS
>A0A6J5FMX2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia caffeinitolerans|TrEMBL
MSSDLPSQPSRRNALKCLAFGGAGTVFVLAGGVLTPVHLALAAGTEDKSAVSGIPLFLQI
SDSHIGFNKEANPDVAGTLKQTIDYVNAMPVKPALAIHTGDITHLSKPAEFDLASQLLSG
LNVTELHTVPGEHDVTDGPQGEYFKRFGQASDNRGYYSFDNHGVHFVGLVNVMHFKPNGL
GSLGDEQLAWLENDLKGRTSSTPIVVFVHMPMWTIYEPWGWGTGDAGQAMEYLKRFGSVT
VINGHIHQIVSKVEGNITFHTARSTAYPQPTAGNGPGPGPLVVPGDQLRKMLGVTSISIS
RHPLAASLSDKTLA
>A0A8E6KQ01|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Paratyphi B str. CFSAN000540|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A7G7XIU5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas protegens|TrEMBL
MPSVSALTADDSVLLVQLSDSHLFAETDGALLGMNTADSLQRVIDLVLAQQPRIDLMLAT
GDLSQDGTLESYQRFRQLTRQIPAPGRWLPGNHDEPQVMQLATGDSDLLQPIIDIGNWRI
TLLDSAVPGSVPGYLRDDQLQLLARSLCEAPERHHLICLHHHPVSIDCAWMEPIGLRNAE
ALFAVLDRFPQVRALLWGHVHQEIDRQRGDVRLLASPSTCIQFEPGSDDFKVEEQVPGYR
WLRLLPDGRLETGVERVHGYAFSIDYGSNGY
>A0A084ZNZ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trabulsiella guamensis ATCC 49490|TrEMBL
MESLLNLPLAGGARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAICASQRECDLIV
ATGDLAQDHSSAAYQHFAEGIAGFAAPCVWLPGNHDFQPAMYSTLQDAGISPAKRVLVGD
HWQILMLDSQVFGVPHGELSDFQLEWLEQKLADSAERYTLLLLHHHPLPSGCSWLDQHSL
RNAGALDQVLSAYPRVKNLLCGHIHQEMDVDWNGRRMMATPSTCVQFKPHCANFTLDTIA
PGWRWIELCPDGSLTTEVCRLEAAQFRPDTASEGY
>A0A1X3IXC9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli TA447|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7K0CNW1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces smaragdinus|TrEMBL
MDGLPIGRRSLLAASGVLGAAGAAAGLGLTLSPARDRPGAPAVVGGHPGRLPAGAGPGRP
PAVPTPEGTTAWSVSVPRGGSGYRRLRPGPSWEYVVRDDQAPAQKGRADRRTTLASFVQL
TDQHVQDVQHPLRFEYLRAGIVTAWRPQEALTVQGNIALLERINALPGGPVTGAPLQFAI
TTGDNTDNHSRLELEWYLTLMTGGTVTPNSGDPLSYEGVQNSGLDLYWQPESARTDNDKK
LGFPRIPGFLAAAVRPVPSPGLRLPWYSTPGNHDVLPGGCFRPHGRFAEFATGDRKLETL
PAAQAEYLWRGVRKGRDIPGAGIDALLASHARTMRNVTADERRAPYSREEYIRAHRSPRF
AGAGPHGHGYTERNEAEGTLYYTFRISPTVVGISLDSNHPAGHYEGSLGTAQLEWLERSL
TTYADDHVIVFSHHTSTSMDNLAPDPARPGERRHGAAELVTLLGRHRCVVAWVNGHSHRN
AITSHGTFWEVNTASHVDFPQLARLLELTDNGDGTLSLHTTLIEAAAPHETAYDDLSPQG
LASLYRELAFNAPSLPRKVPAEGEARDRNTELLLRKR
>A0A420ECU9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alginatibacterium sediminis|TrEMBL
MAFEQFELACADNGDIRLLQVTDTHLFAKDEHNLLGINTSDSYQRVVEEIRHSQQSYDWV
LATGDLSQDHSKDSYRRFANITRQLEKPCFWLPGNHDFRPHTTALSESGIIDAKHLISEH
WQIIMLDTQVTGKPMGLLSSEQLEGLATALQQYPEKSVLICMHHQAVPVGSRWLDQHNLK
NADEFFQVVAGCSKVRAVLFGHVHQNFEMEHRGIAFMASPSTCIQFLPLSAHFALDHQQP
GWRYITLKSDGTISTRVCRLAERTFLPDPDSKGY
>A0A6A7SFI5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|wastewater metagenome|TrEMBL
MSDNTSEPPGGVKPLRVLQVSDTHLYADPAADLAGVPTSGSARAVLDAALAGEAPDLIVA
TGDLVHDGSAAGYERLRGWLADSGVPALVIPGNHDDPVAMARCFAEAPVTWRESVSIGGW
QVIALDSHVPGEPWGRLGTAQLERLDGHLAAADTPVLVAVHHPPVAVGARWLDGIALADG
EALLARLGACGRPAVVIWGHIHQAFEGWYGGVRLLGAPSTCIQFAPLSGEFALDIRPPGW
RELTLHPGGGNETCVGRLSDGAFRPVTDCEGY
>A0A1K2FS08|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces sp. F-1|TrEMBL
MPRTRSVAASAAGVSRRSVLAAAGAVSLSAGVGYALRPTASEAATTAPATRTPAAGSRGP
AAPLAPSAKGTTLDSVATPRGASGYRRLGDGPGWPRVVRTELAAPKSGREGRRTTLAAFV
QFTDLHLQDVQHPLRLEYMRVTDTHSWRPHEALTVPGAVSLVERVNALRGGPVTGAPLGF
VMTTGDNTDNNAHSELEWFMKVMSGGRITPNTGDPRYYEGVQNSGLKMFWQPDSDVRDGD
KALGFPHLDGFLAAAVREVRSPGLDVPWYSTVGNHDALPLGCYGSHGDPYLAEAAIGGRK
LYDVALADAKKLQAAIKNGTDPAAVGYRDFLKAHASGMRAVTADEKRAPYTRSDYLKAHL
DPAYQGHGPAGHGYSAANLDAGTQYYAFRISDDVIGISLDTTDPGGHYQGSIGTAQLKWL
DRTLRENRDSHAVVFSHHTSKSMDNTRPDPDRPGEKRHGGAEVVTLLSRHANVLAWVNGH
IHRNVVTPHRTGGGRSFWEISTASHVDHPHLARIIELTDNKDGTISLFTTLIESAAPHRT
DFADLSQTGLAALYRELAFNAPGASPNLAGTAADRNTELVLEKG
>W0I2C7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sodalis praecaptivus|TrEMBL
MESLLKLPVARGANIRILQITDTHLFAGEDETLLGVNTLRSYSAVLKAVQAEQRHFDLVV
ATGDLAQDHSPQAYRHFATRIARLPAPCVWLPGNHDFQPAMVDVLAECGISCAKQVLIGD
EWQLLLLDSQVYGVPHGELSDYQLEWLAQALAGQPERHTLLLLHHHPFPSGCIWLDQHSL
RNAHMLAEVLQPHQRVKTLLCGHIHQELDVDWLGRRVLATPSTCVQFKPHCTNFTIDTLG
PGWRYLDLLPGGAVQTEVRRLDGTEHLPDTDYEGY
>A0A7J0AAI7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MKIQYCSDLHMEFHDNMRFVKSLPLNVAGDVLVIAGDVGYLVDTTIPHLRFWRWASENYR
QVLMVSGNHEYYNNGDIAAQGESWQKMFLPNVGYYHNKVVRIDNVDFILSTLWSRIPPVD
EFAIQNGMNDYAQILYNKRRLIPQNINDEFERNLSFIKQSVSESDAEKIVVVTHHLPTFA
ALDERHKGSILNTAYATELGNYIADSRITAWIYGHSHHRTDLMIGNTHLVSNPLGYLFCG
ENTNFDDSAVIEF
>A0A7J0AER7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MKIGVLHLTDAHFSTDKDFVCDKVSKIVAAIKYVYEDCDRIYVAFSGDIANTGKTEEYII
AKRFLDSVFSLLNRFYSNKVFPQIITSPGNHDCDFGLDSQSRRILLTNPSYAVLGDDDSI
IKTALSIQQPYADFVKDINKQEFSSELFTCIDDSIGDHNVQFLSLNTAWMSQIKEQPGSL
FFPVKIVNSRLAKGSDICISIFHHHPAWMTPNTIENNRTEFIDFINEYSDFVLVGHEHQQ
RSELNGIIGTETVNYFCGEALGAGRTPISGFQTLVVDIESRNGVIQTYSWNRDLYEKQNE
SPFELKQLYSRLQEFHVRAEYIKSIEAIEIPLGEKQSEIKISDLFVYPDLEKTNDLNKEL
SASYEDSERILDPDFSSTVILEGANQAGKTTLLKMLYLESVKRNAYPLLVSWENIKHKNI
DSGLQRAYEEQYDNKTYEIYAQFDNSTKILFIDNLSSDKFSNIEIRDVIEKLKSRFGKIV
ITTSPRYDSLALIGMNQQDMSYARILPLGYKKEVNS
>A0A1C4DV48|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kosakonia oryzendophytica|TrEMBL
MESLLNLSLAGEARVRILQITDSHLFAEKHETLLGVNTWESYQAVLDAIKAQQRGCDLIV
ATGDLAQDHTAAAYQHFAEGIASFNVPCVWLPGNHDFQPAMYSALQEAGISPAKRVFVGD
SWQILLLDSQVFGVPHGELSEFQLDWLEQKLAASPDRHTLLLLHHHPLPSGCSWLDQHSL
RNAGELNNVLQRFPKVRHLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLHADGTLHTEVCRLQSTKFSPDTASEGY
>A0A8F9HIV4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Raoultella ornithinolytica|TrEMBL
MESLLNLPLAGETRVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRPCDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLSD
RWQILLLDSQVFGVPHGELSDFQLEWLEQKLAEEPERYTLLLLHHHPLPSGCSWLDQHSL
RNAGALDRALAAFPRVKHLLCGHIHQELDLNWNGRRMMATPSTCVQFKPHCANFTLDTIS
PGWRWLELHADGTLTTEVCRLNGVKFHPDIASEGY
>A0A0U1QZ84|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)|TrEMBL
MESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTFHSYRAVLDAIIAEQHPFDLVV
ATGDLAQDHSVAAYQNFAKGISRLPVPCVWLPGNHDFQPAMVGALAEAGIAPSKQVLAGE
HWQILLLDSQVFGVPYGELSDYQLEWMERCLIAYPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAILTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDAVA
PGWRYLDLLPDGGLETEVHRLDSDEFCPDMDSDGY
>A0A7U7I7Q8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas carbonaria|TrEMBL
MPSPPHSSADSSVLLVQLTDSHLFAEADGKLLGLATEDSLRLVIDKVREEQPHIDLILAT
GDLSQDGTPASYQRFEELISTLDAPARWTPGNHDEIEIMREVCNGNDRLDPVVDIGAWRI
VLLDSAVPGAVLGHFDDSQLQLLERALGEAPDRHHLICFHHHPVSIGCAWMDPIGLRNAD
ALFAVTDRFPQVRALLWGHVHQDFDRQRNGVRLLASPSTCVQFAPGSEEFKVGSEAPGYR
WLRLHADGRIDTGVSRVIGIDFEINYSVKGY
>A0A6I8TW37|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aedes aegypti|TrEMBL
MIIVTEEINSGTSGARSPGSGRGSVGTPEVAAAAVEGAVTATIVAEVMQTSEEQEPNVEL
AMDSNGDGDGSESLLSQSPGGTSSSSGRYGHRQSSLALTPEEEPLDSYPRLISDLKFPNL
LPPNPPIKILIAFCKNDPVFEALVTASHRLNFEPTFVKSAETAIEAFQNAATGGHHIIVV
DARYPRIIEADVLGRSIRNSKGSQHTTMVAVVKKNLFEKDDTAVISLLDVGFNRCIIESP
HVSICSSELRQIQHSLVRPQNVISTQQALYTALHRSREAVIITDDSLRAQYANRASEKVL
NMKLDEIVGRSLNDLVTADISNILSHTTRHKDYEGFISTRRKSQETLHIHVRAVPVSCIG
RNPTHLVLILEQTSGTTLSALASDALQALPHGKEVARGSLHSIRRGSFDVRSTASDGLRR
TSLAKLSQLPLEAPITKVLSLLAQVQENCSADESKLLDRVMEFLKREGLYSPQMKEIRTE
DPVATDLIGALLTQGPTNILSSRRSSNDSIIRGGGRPSTGSIVFNKTRESSQLSELLNSA
LSWDFEIFKLEELTEKRPLVCLGLELFRRFDVYNTFCCDEVTFKLWLIEIEKKYHSDNTY
HNSTHAADVMQATACYLQQLSNRETKVMDRMDEATALIAAATHDIDHPGRSSAFLCNSDD
RLALLYNDICVLESHHAATTFRLTMADDKINIFKHLDRESYKLARSIIVDMILATEMTRH
FEHLAKFVSVFGTDVDSKETTHDNDDNQILIRRMLIKCADVSNPTRPLKFCVEWARRIAE
EYFTQTDEEKHRNLPIVMPMFDRTTCSISKSQIGFIEYIIHDMMDAWNSFIEMPEIVRYM
EHNYSKWKLFEEQGINTLSDIKRKQLTLNSETTGSSSIEEL
>A0A0M0HKV9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio nereis|TrEMBL
MKVTSSSSDGSIKLLQITDTHLFEATDGSLLSVNTCDSFQAVVDAIIKQACSYDAVLATG
DISQDHSEVSYQRFEKGIIPLQKPCFWLPGNHDYKPNMSSVMPSQQIQQVEHALLGEHWQ
MIMLDSQVVGVPHGRLSDQQLALLEEKLAENAERHTLILLHHHPILVGSAWLDQHTLKDS
HDFWQVVDKYDNVNAVLCGHVHQDMNVTRHKVRVMATPSTCIQFKPDSDDFALDTLAPGW
RELELKADGSLNTTVKRLPQGSFQPDFNSAGY
>A0A7Y3Q333|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. 1-1(7)|TrEMBL
MNVSPSLSPSDHIKLVQITDTHLFAPDDGCLLSVNTADSFRAIVQAIIEQQIHFDAILAT
GDISQDHSAESYQRFAAGIRDLQKSCFWLPGNHDYKPNMGSVMPSAQIQALEHVLLGKHW
QMVLLDSQVVGVPHGRLSDYQLGLLDEKLTQYPDRFTLVLLHHHPLLVGSAWLDQHTLKD
SDAFWHVVGQHRNVRAVLCGHVHQAMDCEYQGVKVMATPSTCVQFKPNSDDFALDLCSPG
WRELELHHDGEVSTQVKRLRKGAFVPDFTSSGY
>A0A679IUU6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Variovorax paradoxus|TrEMBL
MTTASTNDNTFLVQLTDLHIREPGRLAYGRIDTAPYLERAVQSVLALRQPPDAVVITGDL
TDFGRAAEYEHLARLLAPLAMPVYLLPGNHDDRDQLRRSFPGHAYLGTGADTHGFVQYSV
RVGALRLLTLDTCVPGASHGTLCEKRLAWLGAELEAARGEPVVVAMHHPPFRTLIGHMDE
IGLLEGADALEALLSRYTNVERVICGHLHRAIDVRFGGTIASTSPAQAHQVCLDLAPDAA
SAWTLEPPAFRVHAWSSAERRLVTHLAASGNFEGPYPFHENGALID
>A0A511QAC8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sagamiensis NBRC 104589|TrEMBL
MNWAFSLHLSSDSIKLLQITDTHLFATDEGNLLSVKTADSFNAVVKAILCQQVPFEYILA
TGDISQDHSTASYLRFAQAIAPLKKTCFWLPGNHDFKPNMRDVFPSAQIKAEEHVLLGEH
WQLILLDSQVVGVPHGQLSQEQLVLLDTKLALFPDRYALILLHHHPLLVGSAWLDQHNLK
GADKFWQVIRQHNNVKGIVCGHVHQDMNVMDNGIRVMATPSTCVQFKPNSDDFALDVTSP
GWRELELHANGDITTEVKRLPDGLYQPDFTSSGY
>A0A6I4R129|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. L-22-4S-12|TrEMBL
MPPPAIPTHDQPVLIVQLSDSHLFAEEGGKLLGMDTCDSLQRVIERVQQEQPHIDLMLAS
GDLSQDGTLGSYQRFRRLTDPVARQARWFAGNHDEMPAMREACAGSDLLEPIIDLGSWRI
TLLDSSIPGAVPGFLADDQLELLEQSLHAAPERHHLVCFHHHPVSIGCNWMEPIGLRNPQ
ALFAVIERFPQVRAMLWGHIHQEFDQQRDQVRLLASPSTCVQFAPGSEEFQVDRSAPGYR
WLRLHADGLLETGVSRVTGIDFEIDYSVKGY
>A0A5E4LBH6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKIAIIADTHFGYSRFEEDAFVQAEYALRDAERKADAIIVAGDIFDVKIPRLETLKRAAD
IFSRVRGPVYVVHGNHERRGRDMTNPVQLLSMLSNIKYMHSATEVIEGPSGKVSLTFMGS
VPEELAKNALGKLMEQERGKLPADAFKILVMHQSVSELVYGNEEELSFDDLKALPFDLIV
DGHIHKHHVEMGGKLIIPGSTVITQLRNDEQGERGYVLYDTNARKGEFIPVPSRLFFYNE
MKFENAALAEVKERIEAWIAEMRAKHRDAILKIKLTGTLKEGLCASDLSLSYHDGIYVQN
GLNVESIGEKIKRMREQREEKLSMREIAVRQLRDKLKGRITLFDPLELFEKLAESPEAGA
KYLNIEQ
>A0A5E4IQQ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MNMKAICFSDVHAEEIAIEWAQAMIDRANPEIAIICGDFTTRGPLGFAEDFLDAIKIPCV
AVFGNMDESPVAELLENRGVSVHLKTKKVAGIIFAGIGGSNPTPFGTPSEYSEKEITEML
SGVMVSPQTIFVSHFPPLDTKADFINGKHVGSPALRAFIEKKQPRACICGHIHEAEGVDR
IGKTKIIKVPALQHGKALLLDMENLEVEELRA
>A0A5E4J6T7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MTLDLMIFISDPQLGRGDVNRNVLHAKSVFETAAEMEKTNEYRCRGIIVVGDLTNYGHDD
QLDKYKELYESQSFLVFPGLGNHDYQLNVNDTFENRGATRMVEYLISSVHNVAAKVGVNF
DVNEDSSPTKKTITGSLDYSWDIGNIHYVNANNYPAYQNSWSNFRSDRGKSIAVNIHPCW
EWLEKDLRFARKQGKSIILNIHDMMNNWTDSDAKKFWELCQKFSVSAVFCGHDHAHGDKT
GFYTSPNPCMNGHGIPKFNCGSADWNKYLYAWVEQGGSISPDGYPLDTMNVKIIDSSNGT
CNILPDVWFVRLLRPSEVFIENSGDFVAKYIISFYWGGNKKLESEEQARGSTCGFAIPDD
ATNLHLRMMCKGSDTWKDIMSQDIKNPNGRMYYYHVTGTFSAPYWNLE
>A0A5E4JVU0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKKLDYIQIIILLFVYFFMNLYVFFTFASLFNLEKNLIFYTFFSISFLSIIALTFLERSF
PNPITRFFYIIAVAWSGFLLFFICLIIPYNILEIFFTIPKFIAGIVIFTLGAASSVYSLV
NSLIIHTNKIQIPIKNLKKKTKIIHLSDLHLGTVNNLSYLKSVVNKAILLKPDLVVITGD
LIDGTAPIKPSKLEVLNKIKVPILLILGNHEIYDLKDVYESLSKTKVKILRDETVNFRDF
QIIGLDYGKERAKVIKNVLRKMPLSKTKPKILLYHTPLSPKSLSEFDIDLLLSGHLHGGQ
IFPIHFVAKASYPHYRGLQKKGKFHSYVSQGTGTWGPPMRFFSKNEITEIEIVPEVSLN
>A0A5E4KAP6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MIYALGEKIIGTQKFPSVITPNLGCPKIISVDEILQGKATIDIILADQSGELFYSDDLFK
DAFELVPSFPEDKTNHIQLEINGHPEEITEWNKLFDFSNLEETQLLISSELHYNVFGEGT
KYWLVRAVPKASGSEKIGYETFLRQNKNEILLPTLYDLVFTDNSKRKKVNYHAIQFVENF
KKGFNFIHLTDLHLAQRNDEILGEVLKECNKAVRFRDEIKENYINFNDNFRRFIHIANEL
ADKGELAFVMITGDIVDFVGHGWEDNISESENNWKIFFNIVTGQGTESNKKFQLHDGDNK
LEIFNRGLRVAIFTSTGNHDWRLHPYSLLPYIPGKEGACEKFGLKKEEAENFNYRSFDSS
EYPADDRKKLADELNKESLMRLNMNALDEGWIKDTTKWGRRIFDDFWGRVLSWQGALAGG
LGSGGFLSWINSLSDKIRIFINPLLIGFIGLIGFFLPLTLKWYAERRLRKIIDLLIDNPL
HAEVKALHYYFTHINPYFDYAFSIGDNHFILMDTGADVVTITAEDLMDEKKLEDLKKISI
QDNLLGFSPDTMAFDDREAYYNWSQIVWLDRVLSAASQKAKTGRIILGLHAPPVNHDPKC
NMDELLEDNKKNGYIPEKTCNLTYGTINHFLSQFFFLCLGLRENPNRKNLLLSSDLKKVD
LVLSGHVHTNAEYRLGIEEESKENKIRIYYDKYSRNPEQFDEKKPFLLVTASCGPQYNKD
YITPYWRMVRIDGKNRITSFSTENLREWLKHDT
>A0A5I0ENW1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Kenya|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2U4GR47|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio campbellii|TrEMBL
MQSSSDSIKLLQITDTHLFEADEGSLLSVRTADSFAAVVQEILNHQVQYEYILATGDISQ
DHSAESYQRFAEGIAPLKKDCFWLPGNHDYKPNMGSVLPSPQIQAAEHVMLGEHWQLVLL
DSQVVGVPHGRLSDQQLALLEEKLAENPQRHTLVLLHHHPLLVGSAWLDQHALKDADAFW
QVVDRFENVKGILCGHVHQDVNVLYNGIRVMATPSTCVQFKPDSDDFALDTESPGWRELE
LHSNGDITTEVNRLPDGQFQPDFNSNGY
>A0A486X9Z4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured Avibacterium sp|TrEMBL
MVDTYTYPTDNDVVRLVQITDPHLFKDENGELLGINTQASFNQVLSEIKQSDFDYELVLA
TGDLVQDSSSEGYLRFCETVQCLEKMVFWIPGNHDFQPKMFDILNHNNGNINPLKHLLIG
EHWQILMLDSQVFGVPHGQLGQYQIDWLLSKLKDYPERYSLVVLHHHILSTNSAWLDQHN
LRNALDLAYALSPFNNVKGILYGHIHQAVDSEWKGYKVMATPSTCIQFKPDSNSFALDTL
QPGWREIELYNDGRIETRVKRIQQATFLPNMLGEGY
>A0A1A8RUQ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothobranchius rachovii|TrEMBL
MLKRSRSAQGVTPSDENPDPLVGQFSSGCTLGMEACKVHRRFSGNLQLPPLSWRQAETER
DRGRPLTPEEDPVTRSRPTSLPIVSLPRIDITQADSDSLEVENAPPLCCSPSDQQASPGS
GLVLHPNMANHSQRRESFLYRSDSDYELSPKSLSRNSSIVGELHSEDLIVTPFAQVLASL
RTVRNNFTTLTNVQCTSTKRSPAANQPCVTKVCLSDESYQKLAMETMEELDWCLDQLETI
QTYRSVSEMASNKFKRILNR
>S7MGQ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Myotis brandtii|TrEMBL
MTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQ
VLASLRTVRNNFAALTNMQDRAPSKRSPMCNQPSINKATITERWMLCLYNTKHLEEKNSQ
PKLIKKRFISKVCF
>A0A2K6UBL9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Saimiri boliviensis boliviensis|TrEMBL
MQGPPAPAPAPGPGSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENGLSSGR
SALDPQSSPGLGRVVQAPVHHSQRRESFLYRSDSDYDLSPKAMSRNSSVASDLHGEDMIV
TPFAQVLASLRTVRSNVAVLAHQQCRGAAKQGPVGNLSSSHQPPPPAEDTGQKLALETLD
ELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISQTFLDQQT
EVELPTVTAEEPPKPVSQISGLHGLCQNASLSSATVPRFGVQTEQEEQLAKELEDTNKWG
LDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLLLEGHYHADVAYHNSL
HAADVAQSTHVLLATPALESELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSTKQR
LSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYPDRIQVLQSLVHCA
DLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIA
HPLWETWADLVHPDAQDLLGTLEDNREWYQSKIPRSPSSLTNPEQGGPDRFQFGLPLEEA
EEEEEEGEEPALDKEALELSDTELPPEASPDPGDLPLDNQRT
>A0A402DJ33|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcystis aeruginosa NIES-4285|TrEMBL
MRPFWLESLQVERLTIAIAGLPAHLQGIKLVQWSDLHCDEEHLPEAVLQEAIAITNQEKP
DLIFLTGDFITDSPQPIFALADSIKALKSQGGIYACLGNHDSYLPQARETVRSALTSVGI
RVLWNEIVTPYGENFPIVGLADYWSGEFLPQILEQISPDIPRLVLSHNPDTAMILKDWRV
DLQLSGHTHGGQVTIPGIGSLPIILEELRRSLPEPYRPWVPLYREFSKVVRYWQWSEGFH
RVGDNQLYVNRGLGTYFPGRLFCPPEVTVITLVNSTQS
>A0A3R8MZN8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bibersteinia trehalosi|TrEMBL
MSDSYQWQTDADTVRLLQITDSHLFSDDHGELLGVNTNDSFQAVLNEINESSFDYDLVLA
TGDLVQDHNREAYHRFGQMVKTLEKPLFWLEGNHDTQPQMGKALSIYQQIQPHKHILAGQ
HWQIILLDSHIENLPRGELNRTQLDFLTQMLARYPERYTLIALHHNILPTHSAWLDQHSL
RNSEELAEVLFPFKQVKALIHGHIHQEVDAIWKGYRVFATPSTCIQFKPNCQHFTLDFLP
QGWRELTLLPNGQIETTIKRLKTNEFLPDFQSNGY
>A0A2S9XEK4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enhygromyxa salina|TrEMBL
MRPSLLLAILTSAQLALLGCTAVLIESNDVGGSEAETAQTSESSDGDTDTGDTGDGDGDG
DGDTDGGDGDDGDGDGDPSRFRVVVIADLHVPGPDYTGDDDSLLLARERLLETRDQIAAI
EPPPAFVVVLGDLVHEAYGSDDLVWYQTNANAFAEVSEIFDGFGIPVYPLYGDSDYDVPT
TPKTFSHQVFAQIFATDPYYTVDHLGWRFVFANSQYGQTYDKGTNIYDPALGSFGSTQLT
WIGDQFSAGMPTVLLSHFPLYTLALDEAPNNGPYPDLETVLKADGESVALVLSGHDQQWT
NLPATYAAPHIVFGSTRYDSDNFLLIEFTANALQYEILDLAKVGWGTQEAETWIYDGTPM
PAG
>G0QR60|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ichthyophthirius multifiliis (strain G5)|TrEMBL
MGVCMCNNCPNKDPSDFKFLEYNEMTLQLDDEGNIKQLNNAQSSTNKDLLEDSNIKAGEQ
QDDKRKKRGKNKVQAVRDNFDKELQIFENVKKIEMHMTKEEINQNIKFLSNHFVFALLSN
PDKEEIVKKMFYCQNTSEYVFKQGDQASSYFIIDKGQCQIIINNDAKKTLKQGDCFGELA
LLYGAPRSASVKTIGKCSFWAIDRNTFKKAIADVVQKEYQENRAFIDKITFFDKMTSEQK
DAIANVLITQVFKKGDIIVNDGDMASSYYIIKKDQLEFIKMIKKLDCLKLVIHSVNKHFM
KIKTDQRLLKLWKIILDQLLWEEI
>A0A4R0PQG5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. IC_126|TrEMBL
MPASRGLPPQPPATIILLRFRQRRRVLAAPLIEKDSVLLVQLTDSHLFAEAGGKLLGMDT
GESLQRVVDLVLAEQPCVDLILATGDLSQDGSLASYQRFRQLSERIDAPARWCPGNHDEL
PAMQEAARGSEMMAPVLDVGAWRVIMLDTLVPGSVFGMLRDDQLELLERTLQDAPQRHHL
VCLHHHPVTIGSRWMDSIGLRNRDALFAVLDRFPCVQAVLWGHIHQEFDDQRGDIRLLAT
PSTGVQFAPGSEEFQVDTLAPGYRWLRLHDDGRLDTGVSRVVGMTFKVDHSIKGY
>A0A433NY86|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium polaris|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKARQDAFDLIV
ATGDLAQDHTLQAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPERFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSTVLERYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A5E7WA02|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADSALLVQLSDSHLFAETDGTLLGMNTRDSLQKVIELVRLQQPQIDLIIAS
GDLSQDGTLESYQQFRDLTRQLDAPARWIPGNHDEPRIMAEAAVQSTLLEPVVDVGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPD
ALFAVLDRFPQVRAVLWGHVHQEIDQVRKGVRLIASPSTCIQFEPGSDDFKVSDQAPGYR
WLRLLPDGRLETGVERVTGFDFQVDYGSNGY
>A0A7Z9XS46|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chromatiaceae bacterium|TrEMBL
MPMNSNSQGSDLHLLQVSDCHLYADPAGSLLGLNTLDSFQQVLDSACKNQTPDMIIVTGD
LVHDGSKKGYKTLAKTLAGTGCPSAAIPGNHDHILSMQNVLKKHHIPAGGKIDLGNWRLI
MLNSQVPGKEHGHLSPAELELLDEALANAPPHVLIFLHHQPVPVGNQWLDKIGLDNASEL
FSRIKDNPAVKGIVWGHVHQPWEGQLGHIQLLATPSTCIQFAPGQDEFGLDSQPPGWRML
TLGKTGDLHSQVHHISRMPKGLIADSGGY
>A0A7Z2YIP1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSSLTTADAALLVQLSDSHLFAEADASLLGMNTRDSLRAVIDLVLKQQPDIDLMLAT
GDLSQDGTLESYEAFRQLSGLIEAPARWIPGNHDEPQVMLEAAVKSTLLDPVVDIGNWRV
TMLDSAVPGSVPGFLAEEQLILLANALSEAPERHHLVCLHHHPVSVGCVWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEVDRVREGVRLLASPSTCIQFEPGSEDFAVGSQAPGYR
WLRLWPDGRLETGVERVVGFAFTPDYESNGY
>A0A5E6YFE9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MLTTADPALLVQLSDSHLFAEANGTLLGMNTRESLQKVIELVLGQQPQIDLILATGDISQ
DGTLESYQQFRQMSAQIDAPARWIPGNHDEPMIMAEAAVQSALLESVVDIGNWRVTMLDS
AVPGSVPGYLQDDQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPEAFFEV
LDRFPQARAVLWGHVHQEIDRERNGVRLMAAPSTCIQFEPGSEDFKVGEQAPGYRWLRLL
PDGRLETGVERVTGFDFTVDYGSDGY
>A0A5E6TYT4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MAFNKFTSVVLGVCLWASVASAQAITGTPKHMVFASDTQYPWTDKTDSRHPESDAEFDVR
SKWLVDTQLSSIADFRRQHGSQAEVPLMINGDITAFGHGWQRSFMKEMLSKHFKGEYLYG
LGNHDYENNVDDCFTNSCAAGSIVDFKEHHEGKVDSFDLNITDGFLGKTYSGSLAYSKKI
GEVHMVQLNNEPTYTTRISHPLNPTTFEINDALDWLEKDLRLARVGGYAIIINMHKPFSD
KVNPAQNQRFLDMISKYQVTAVFAGHLHEEGGNAYWKGKVPMYLSGSTSQQTYLIASFTE
DRKQLEVYLVKDNQWRNRTLIETTPVHSIFARRP
>A0A7V8UHW4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas brassicacearum subsp. neoaurantiaca|TrEMBL
MPSVSSLTTADAALLVQLSDSHLFAEADASLLGMNTRDSLRAVIDLVLEQQPNIDLMLAT
GDLSQDGTLESYAAFRQLTAGIDAPARWIPGNHDEPRVMLEAAVKSTLLDPVVDIGNWRV
TMLDSAVPGSVPGFLAEEQLILLANALSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRVREGVRLLASPSTCIQFEPGSEDFAVGSQAPGYR
WLRLLPDGRLETGVERVVGFAFTPDYGSNGY
>A0A2U1TU25|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Brenneria sp. CFCC 11842|TrEMBL
MESLLTLPVANGARIRILQITDTHLFAGEHETLLGINTYRSYHAVLDAIQAQQYAVDLIV
ATGDLAQDHSLEAYRHFSRGIRQLSAPCVWLPGNHDFQPAMVDALAEAGIAPSKHVLLGD
KWQTILLDSQVFGVPHGELSDYQLEWLERTLQSQPDRYTLLLLHHHPHPSGCTWLDQHSL
RNAHSLAAILARYPRVNTILCGHIHQELDLGWHGRRLLATPSTCVQFKPHCTSFAIDDVA
PGWRYLDLMPDGQLETEVFRLPGNEFLPDMNSDGY
>A0A6V9XJ13|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Decatur|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A0A1WUU5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Zeugodacus cucurbitae|TrEMBL
MDVKFPTVLPPNPQLKALLVFHKSDNICEVITEACHRQQLDVTVARTKEGALDTLTNTNE
EFYHLIIIDARSTKHLDAEYIARSIRHTNGHHFTTIIAVVKKSFFEKDDVLIALLDAGVN
RCVPETTNLSMCNIELKQILHSIVRPHNVMSTQQALYTALHRLKEVILITDNHLRIQYAN
RAAERLLNMRMDEIISKPLADIFISDVSTIMIHGRKNKEFDEILTVRRKGQEDVAMHVRV
IPVACIGRTPTHYVFNLDVPGSHGDFVATLPQAREAPRGSQHSIRRGSVDVRSVASDGLR
RTSLAKLTSLPLEAPITKIINLLSQVQENCSPDEARLIDKVMEFLKREGLYSPQMKEIRT
DDPIATDLIGALLTGPSLYSSRRSSNDSIIRVGGRQSTCMPAKMKATPHIMELLEESLSW
EFDIFKLEEITEKRPLLYLGMEMFRRFNVFATLNIDENVCKSWLAVIEANYHANNSYHNS
THAADVMQATGCFLTQLAAKDMGMDRTDEAIALIAAAAHDVDHPGRSSAFLCNSRNTLAL
LYNDLCVLESHHASITFRLTLSDDKVNIFKNLDTESYKSVRSVVIDMILATEMTRHFEHL
AKFVSIFGSDEEPKDIVQSEEESSILIRRMMIKVADVSNPSRQPSYCIEWARRIAEEYFT
QTDEEKAKTLPIVMPMFDRNTCSIPKSQIGFIEYIIQDMMHAWDSFIDMPQLVTYMQINY
SQWKKFEDQGVHTLADVKSKQHSLSVKKSAK
>A0A5C2R7K3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae biotype aegyptius|TrEMBL
MKNAFVYQTEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLKPPMNVAKHLLLGEHW
QALLLDSQVYGVPHGQLSQHQLDLLKETLGKNPERYTLVVLHHHLLPTNSAWLDQHNLRN
SHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQPG
WREIELHSDGSIRTQVKRIQQAEFLPNMQEDGY
>A0A231HEY1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nocardia cerradoensis|TrEMBL
MTEQHPQHTDPRDPHAMTRRQLLRHSAWFGAAVGLTVVGGEVISHVAGAAPATSERPTLR
FAQISDSHIGFQGAANANVTDTFTEAIGQVDALGYTPDFVIHTGDLTHLATPAQFDQVRQ
MMSGLSTPHIFTVPGEHDSTDDGGQRYRDVFGQGTRGDGWYSFDIAGVHVIGLVNTLHAQ
NLGHLGQDQIDFVRKDVAGLSADTPIIVFSHIPLFAMYPQWGWGTDDAAQVLNLLRRFSS
VTCLNGHVHQLFTKTEGNITFFSGTTTAYPLPHPGEGPAPKPVTLPAGKLHAALGIREVS
YRQGRQLLAIKEQALR
>B3NPQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila erecta|TrEMBL
MGCSPSTLPPAPSAGQTGERGSLPLDASEKDESRLFCIKLRRSRLRRCSCGGVTLQPPSD
GNGSTAGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHSVVRRATGSTG
TSGTSSSGGNSRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLVFH
KSDSICEAITAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSSKNLDAEH
IARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQIL
HSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLE
DIFVSDLSTISEQCKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVP
GGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKII
NLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYS
SRRSSNDSIIRTGSSTRTAAIVPAKMKSNPIIMELLDESLSWDFDIFKLEEITDYHPLLY
LGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLA
NKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITF
KLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPRDHNP
QTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMF
DRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLAEI
MAKQPPVGKMANSKXHTAFRRLFSGLLKPLPAQAPGTSTIGENEMEDVL
>A0A737C5V3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. arizonae serovar 18:z4,z32:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYGALQEAGISPAKHVLIGE
EWQILLLDSQVFGVPHGELSEFQLEWLERKLANAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSLLAHFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A564L0B5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella spallanzanii|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQILLMDSQVFGVPHGELSDFQLEWLEQKLAEVPERYTLLLLHHHPLPSGCSWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A395L4F9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ensifer sp. M14|TrEMBL
MTKLIIFTDLHMVPEGATIIGLDPYQRLANGIAHVNRYHADADRVIFTGDLTHYADRASY
ERLKTLVDQLSPPAAIMVGNHDRRDVFLDVFADAVTDDDGFVQQAIDFDDCRAILLDTLF
APPYDYPNSHAGLLCHKRLAWLDRQLAVAGDRPVLIFMHHPPHATGFTGMDMIRLVNEVE
FYALAKKHGNVRHIFAGHVHRTISGSSRGIPFSVFKSPVHQQPMPFDAPDASLSVDEPAA
YGIAVVTRDGVLVHTEDYEIARRDAAIA
>A0A0J8V9Y6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium swingsii|TrEMBL
MQTYTLPQQGPDKVVLLQITDTHLFDDISGSLLGIETKKSFHAVLDAVDDAARPFDAIVA
TGDISQDHSENSYQRFADGISRWKQPCFWLPGNHDYQPTMRSVLPSQQIKPCEQVLAGDH
WQVILLDSQVPGVPHGALSSTQLEMLDSALSTHPERHALVLLHHHPLEAGSYWLDQHQLH
NNEALWYVLDQHPQVKAVLCGHIHQELDRMYRNVRVLATPSTCIQFLPDSNDFALDQVNP
GWRYLELYNNGDICTQVSRVQGPQFAPQFDAAGY
>A0A4R3VRQ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Samsonia erythrinae|TrEMBL
MESLLTLPAASGARFRILQITDTHLFAGEHETLLGINTYRSYHAVLDAIKARQDTFDLIV
ATGDLAQDHTLEAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALAEAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLNRQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSAVLDRYPQVNTVLCGHIHQEMDVDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPDGRLETEVHRLSGSEFLPDMNSDGY
>A0A330GB90|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAEHRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSAPCVWLPGNHDFQPAMYGSLHDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVNNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLTGAQFRPDTASEGY
>A0A800YMC6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae complex sp|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEKRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGD
QWQILLLDSQVFGVPHGELSDYQLDWLETKLAAEPNRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDGVLAKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLTGAQFRPDTASEGY
>A0A7S6W5H6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. YH12138|TrEMBL
MTLRDTPQYDWTLIQISDTHLMDQEDLEFVRMNPEQSFHDVIQQIQLNHHHIDTLVHTGD
LAQVPVERTYARYLEYMQQQPFPFYQIPGNHDEASCFPFHQQEDRAHCIALGNWCLILLN
SAVKGKVDGWVSQQQLEQLDQLLTAHPQQHIIVACHHHPFAMQSHWIDQHKLKNAEHLID
VLSRHDNVKIVLCGHVHQDSSNQWRNIQFLSTPSTSVQFKPHSENFALDEALPGYRALYL
NDNGEFKTEVVRVKLKQPQINVEISGY
>A0A1Q9NQI1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Thorarchaeota archaeon (strain AB_25)|TrEMBL
MRFSFDSRFTSDCGRDIILTLFSGITRLKCCILDGKPVMETIFDDRGMIITHHDTSVLLI
SDIHLGFEEELAESRGVQFPPQHPVILERIERLVKRHNISHLFIIGDVKHTILTDRYYNW
EIIPEFMKTLANQVKTTVIPGNHDGDLRALLPRDIIVTDVHGILIGPKYEQVGLLHGHSW
PSADILDAKMIVIGHNHPTIRRFRDASVPEIGRSSRRRYAGTVPVVLKTKLNRNCVRSAM
GMLEVPEDSGCILITLPSFNELLSGISVNYPMSEFHGPFFENMCARLSESEVHSTNGIYL
GSIEWFRQRFNEMIKSKSTGD
>G5SGZ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Wandsworth str. A4-580|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A085G6N6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ewingella americana ATCC 33852|TrEMBL
MESLFTLPLVNGAKVRILQITDTHLFAGENETLLGVNTFRSYRAVLDAIKAQNRGIDIIA
ATGDLAQDQSLDAYHHFARGINELSTPCVWLPGNHDFQPAMVDALLEEGIHPSKQLLLGD
HWQVVLLDTQVFGVPHGHLSDHQLEWMERCLQQNPDRFTLIMLHHHPLPSGCTWLDQHSL
RNAHMLAEVLARYPKANTLLCGHIHQELDLDWHGKRLYATPSTCVQFKPHCTNFAIDTAA
PGWRYLDLYPDGRVETQVMRIESDEFRPDSDSEGYE
>A0A506NNV0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea anthophila|TrEMBL
MDSLLTLPVANGSEIRILQITDTHLFAGKHESLLGVNTWSSYEAVVEAITAQQRDYDLII
ATGDLAQDHSVEAYQHFAEGISRLPRPCVWLPGNHDFQPAMVDTLAAAHINAHKQVLLGD
QWQIVLLDSQVPGVPHGMLSDYQLEWLDNALARFPQRHTLVLLHHHPLASGCTWLDQHSL
RNSHQLDAVLQRYPLARTLVCGHIHQELDLLWHGRRVLATPSTCVQFKPHCTSFAIDTVA
PGWRWFTLHPDGGVETEVNRLDTDAFRPDLDSEGY
>A0A2D0L7V1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus sp. KJ12.1|TrEMBL
MESLLEIPVAKGATARILQITDMHLFANKGGSLLGINTYRSYHAVLDAILEQNIDIDLVV
ATGDLVQDQTPGAYQNFVEGIARLPAPCVWLPGNHDYQPAMVDVLAAAGISPSKQIFIGQ
HWQLIMLDSQVQGVPHGELTEYQLEWMSKCLDEHSDRQAIVMLHHHPVPSGCTWLDQHSL
RNAPALAECLKGKSQVKTILCGHIHQELDVMWNGIRVIATPSTCVQFKPHCTNFMLDTVA
PGWRYLELPVTGGGEAELQTQLYRLKSNEFCPDLDSDGY
>A0A644VYX7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MNISLFFILFTIVFAFQTLIIKKRLINKLDFNYKTKKYLSLFLYLTFFGVLMYPMARYFP
VVPNWLYFLLSLPIGMIFLTFIITLLHEIISFGISKTKYTKNRREFFKKGLDIGVISAVI
ATNVKAIDNARHVELEVVDVKINNLLKPYIIVQISDIHIGGLITKNFIKSMVDKINLLNA
DIVVITGDLVDTKLEFARPALDELKNLQSKYGTYFIVGNHEYFHGVKPIIDYVNSLGIKT
LENENVYIGEKDEGFYLAGVYDRFGFRYGSYIPDINKALENCENNPTILLAHQPKYINEI
KDTKNIDLILCGHTHGGQIFPFNFLVKLEQPYVKGLHQHNDTTQVYVNKGTGFWGPPMRL
GASSEITILRLS
>A0A644UFD6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MSRILAATLILFTMLLVISSGCVSQTGPLNTTELTVVPVDPGTNLTITPENLSIYHYNGY
GQWTDGAGVGITVRDDIAGKMTPSEPGVKLLSFAVITDTHVTDEESPLQVIALGYLSPFP
SAYSPVSMYSTQVLNAAVRTINEMNRASKLDMVLSLGDAVNNGQYNELRWFIDVLDGTTI
QPVSGGAAGKENIDYQKEFSAAGLDIPWYQTIGNHDQFFTGVFTVDENASRILRGDTVAN
MRLDVTVTGDPSLTGYYMGVYNGSDPNGAIIGIGNASGFASAPKVVADQNRHALAENGSR
IGFMQEFLNSTSLPFGHGFTEEMIEADFASYSFDPVEGVRIIMLDDTTADGSTIGDIWAH
GRGSLDAERFAWLKAELQKGQDDGVLMIIGAHIPIATMAEGSPSGWSLKSEVSETELITE
LQKYPNLLMWVAGHNHRNTIMPVGSPDPAHPEYGFWVVETASLRDFPQQLRTFEIIRYSD
ELVGIKTVCVDVDVQGDALAEKSRSYSIAAAQMVNKTNVAIENAELLVRVK
>A0A644VPE2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MIKRGILIGLCLGFLLTGCDLIEYHPYDVRIDGETNINLKNIEKIQQQCAGKDTIRFAFM
GDSQRWYDETADFVKHINKQDSIDFVIHGGDISDFGITKEFLWIRDIMQGLRIPYVALIG
NHDILGNGKEVFEQVYGDENFAFIAGNTKFVCMNTNALEYDYSHPVPDFDFISREAADSA
RYSKTVAVMHVKPYDDQFNNNVARLFHAEIKKFPSLQFALHAHNHKLQTTDVFKDGIIYY
GCASMKQRNYMVFTLTTNGYSYEVVNY
>A0A644Y0V6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MRKFILFLTLFFSLAASASKPLKIGVISDIHFLSKELTAEGDALAAYERATGRNIRDSHE
VLDTVLLNFQKERTDILLISGDLTNHGERQSHLDLIEKLKTIQRNGTKVFVVPGNHDVNI
PDSKAYTGEKPVPVKSISKEEFAEWYAPFGYGNALKRDDSSLSYIAGINENTWLLCFDTN
RYAEYKTTSISGGRILPSTMDWALDILREAKAKNITVLGMMHHGLVEHMPYQSTFFAEYL
IEEWEKNAGILADAGLKVMFTGHFHSNDISLFTSPSGNTIYDVETASLAIYPFAYRTMEL
IDGKLSIDTHFVTSVSGNPDLAAQSRSQLETVTRRVAKNRIKNLGVSFPVQTEDALVKLI
VKMNLMHVRGDEAPDEEMKEAIREFAGLLGSEETDSDFQLDFPPADNRLVIDLTEKVF
>A0A644ZMP5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKRTISSVFFFWVITSFFFVEAQHARIGVISDLHYTHPALIVEKGKALEDYLRRDRKLLL
ESDALLRKSVENLLCEDVNVVLIPGDLTKDGELVSHRGVVELLSPLREKGVKVLVVPGNH
DIDNPDAVSFHGGVTHKVESVTPAEFKDIYSDYGYDSALSLDEHSLSYVNEPVEGLRIIC
IDACKYRDNTFISRGAKKDSCVTHGTVKPETMNWIKNEVRLAKLLGKQVIAMMHHGVVEH
FDHQSFFASPYLVDNFEWVQQSFMEAGLNVVFTGHFHASDIARIEDEKGNYLYDIETGSV
VTYPCPYRVIDLSNNHLDIQTKLTDSIDFPIPSGMNFQAYAKKMVDVGFNEMISALISEY
HSSLPVYLPRWLKGIIRIPDAEKFTDMVLFNLSPSAVEMLVAHYGGNENNIENAHRHKEE
LLLAIDSSVRDLCKASAGSLSGIIEKLVVRSKTIKKTKQAVSSIWENTFLTGKGVVKGRL
MDNSINDLNYLLTLNTNENINNGNFYANENVNDEVEVKLFSE
>A0A644U9I2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MNILAISDVHGNENNGLYSYLNNNNVDLLIISGDITNFGPVDFVEYFMNKLSNHGTKIFA
VPGNCDPDDVEGKIIDSNAICIHDNVVEYENLVIYGFGGSNPTPFDTPGEVDEETLYKSI
KKVLDSKDINLVKESSDEFPNGRISILVTHAPPKNTEADKIVNGSHVGSESVRKIIEEYK
PRLNICGHIHEARSMDMLDDTIIINPGMLEHGHGCLIEIDENNNIIANFVNLD
>A0A644U2G1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKRNQLKWWSIVASAVLMFTAISCHKESVSSTTGDNPFDITNGGESQVRNKIVVISDIHL
GNDLNYAECVAHLPRLVEFLTDIRESKTVSELVIAGDLLDEWYIPSRTDTYEGKTQKEFI
QKIATQNKGVIDVLNGIIKDENIKVTYVPGNHDLIVQEDNVELILPGINQARDNNRPGIG
TYYPIPQIAIEHSHRYDFFCALDPYSNQNIAPGTTLPAGYFFTRIAVNSVTNYPEAGEIT
PVRDVTLNSADETQVNNFIYYNTWKSVLTSLIPVKDNFDDKIIVTNVGNFTGSFSINDVI
PFNKPDGSIDMNLFSGACSQSGWEKRLAYNNVPVITSIKDAIPGSLHTNFLDEQSNVQYF
QNQNSEVRIVVFGHTHVPMLKSFTNSKGEACIYANSGTWIDKKTKQGESVDQDNENMDFI
VIAPQAADNSMIKVERFQYRKQAHISLESRSIKL
>A0A645DG20|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MNIKNKSLLKTAVLAGAAAYLHLQNTWIQKTEYTIPVKNLAPENEGLKIVQLSDIHLPKE
KIDLDKLIEMTKEADPDFIFLTGDQIQGDHPFDPSVAEKLFRKLAAIAPTYAITGNHDRH
SPMFHIAVDMYKKTGVRFLDDEAVSVLAKGRKPVVIMGLSDKSAAIQKITKDFLKKIRLR
KDWQGQTRLLLAHRPEHFLKYHVNPEKSADITFAGHAHGGQIRIPRLGGLYAPGQGRMPQ
HTEGVYLLPTDPDKKLVVSRGIGGASFPFRINNRPEMVIVTLTNGSVSESL
>A0A645BU38|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKKKLIAAIVLLFSFFGFLFFENQAKTYYPPQKEYHRIVILSDAHYPSKLSAEENANGRQ
AKIDNKLSAINDVNGWNDVDLVVFLGDIVEKLGNESDYSQAKEFVDKLTKPKALIVGNHE
FMYEDHLTASGKLKWASPELREEKLERFKNTFQLNDLYYGRYIDNYLLIFLSPDVTNGRY
LTEISTEQLSWLEKTLVANKTRPTLIFFHAPLAGTLASYNKDANTPNFVAQPEKQLHDLL
MNNPQILLWVSGHTHTPATNPSFDATINFYEGKILDLHNPTLDGKTIWTNSIYLYPDKIS
IRTYNHQTGEFVENLDRTIPITFTAK
>A0A645CCT6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MTLVGGVMVRKFIRFMVLLIIILVGFPIGSFAAREREEVPILQIPVISDVHIGDGKGENK
ILRVLKEYKTLAPGYRAIAIVGDMTDCGLEEQYDGFNKILKENINPQVERIVAMGNHEFF
EGRFFKKPGLTDEILTDRFIRKTQMPGVYYDKWIEGYHFIVLGGEKSNLSDETIGDKAII
SEEQYNWLEKTLEKKSQPEKPIFLFLHQPIDNTVYGSKQWGGGLSDGRLYNLLKRYPQVI
LFTAHSHYPLNNPRTLYQDGFAMVNTGAIRYILEEDGTVLAGDMQGLLVNVYKNRVEIKA
RDFSKGIWINKYTINVRQDISFTDNFRDMF
>A0A2T7B766|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cronobacter turicensis|TrEMBL
MESLLNLPVAGGASVRILQITDTHLFAGKNETLLGINTWESYQAVLSVLHAEQRECDLIV
ATGDLAQDHTPEAYEHFAAGIATLPAPCVWLPGNHDFQPAMFSTLHDSGISPAKRVFAGD
RWQVLLLDSQVFGVPHGELSDYQLEWLERMLQQAPERHTLLLLHHHPLPSGCGWLDQHSL
RNAQALDDVLNRYPQVKHLLCGHIHQELDLDWNGRRLMATPSTCVQFKPHCAGFTLDTVA
PGWRWLNLHPDGSLTTEVCRLEGAQFRPDTASEGY
>A0A5H8H7J0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella blockley|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A3T3EN91|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella muenchen|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2A7MLT9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clostridium neonatale|TrEMBL
MALYTISDLHLGFNVEKPMDIFGDKWKNHCDKIKNNWLEKITDEDTILIAGDISWSLKAE
DSVYDLDWINELPGNKIISKGNHDYWWTSISKLNSMYEKTKFLQNNYYTYKEYAICGTRG
WICPGANSFTSKDEKIYKRELIRLRLSLEAAKKDNYNSIIVMLHYPPTNEKFEESEFIKV
IKEFNVEKVIYGHLHGPVLYGKLFEGNIDGVEYILTSADYLDFNPIKIL
>A0A5I2ZG90|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Mississippi|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFCAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A7R9LC69|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oppiella nova|TrEMBL
MPIYGNIVGAEPTRAELQLPFTRVCDGIAGTPVNRIPIMAKQVLDLYELYRLVVARGGLV
EVINKKIWREITKGLNLPSSITSAAFTLRTQYMKYLYPYECEKEKLSSPDELQSAIDGNR
REGRRSSYGQYPEMVGATPPPPHMNRNQGSHHHTSPLSLVSRQLNGHNSQGLSSGEEDNG
SISSTPTHHFSHHPLPQSEALNLEVNPRNASDATNRALETSRKIMEDALGVTPAKRFLTD
EERFLMHAALPSVQIKVMNRDGRSQIESQLAVSMEINGIVYHGTLFAHHSSDQTGFAYGC
GHSSSSNDMPALNQQNYGSENRRASIEMNGTHLCNNKDMRESVVLLVFDKPDAQSDALKW
AAERLSFDTHLVHNCESALDRYEEERHHLVIIDSRQSSHMLDSSTLCRSIRNIKGSEYTC
IVAVVKKSLAEKEEAGVLSLLRIGFNRWMLESCNLGVCLNELVQLEHNDIAIQCKLKASH
ALFTALDSCKDGVMVTGPNHDIQYVNQSIEKLLGFRYDEMIGKNAYDLHRSDSFKTDIVD
SINMHLNKGKEWEGTILHRRKSGECIPLWSKISPIEVHNGRQSFAKFHAMTIEAPITKNS
PVFVAQALDKVLEILKNSELYCPQFGNQQTKPDDQTANDLVSGLMSSGTKQSTVRRMSHE
AASNKSSVGVTPQTPTQMPSLTNAPNNIKNLLDRDYDWGFDIIELERVTQKRPLVWLGLS
VLSSFNVCQTLKCDESTLRNWLTVIEANYRDNPYHNSTHAADVMQATAYFIRRPRLKAVF
DPLDEAICLLAAIVHDVDHPGKNSAFLCNSNHELAILYNDISVLESHHAAHAFHLTVSPN
SDQINIFKNLERDIYRDVRQSIIDMVLATEMTKHFEHISKFIHVFTKSVNMDEGFSGNDN
LLETVPESPNMITFSTPENIVLIKRMLIKCADVSNPARPLKLCQVWAQRIADEYCNQ
>A0A0F5EQM9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Avibacterium paragallinarum|TrEMBL
MVNTYTYPTEKDVVRLVQITDPHLFKDENGELLGINTQASFNQVLREITQSPFDYELVLA
TGDLVQDSSNEGYQRFCESVQCLEKTVFWIPGNHDFQPKMFDILNQNNGNINPLKHLLIG
KHWQILMLDSQVSGVPHGQLGQYQIDWLLSKLRDYPERYSLVVLHHHILSTNSAWLDQHN
LRNALDLAYTLSPFSNVKGILYGHIHQAVDSEWRGYKVMATPSTCIQFKPDSNTFALDTL
QPGWREIELYSDGRIESRVKRIQHAQFLPNMLSEGY
>A0A3S4F058|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A3U1TLY8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica I|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPCVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A3V3Z6G2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Pomona|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A3V7EZE0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella derby|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A3V7ITA7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella rubislaw|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5H9M5K2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Sandiego|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A7URN7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles gambiae|TrEMBL
MDISKVLIRQLSAREWRRFVAFRSLPADSIDPAFRQQILADYDVHFYEYGELAASSAQEV
VSADTVTFAVGEPTAGSSRPQQRWPEGSDGKQRQLVESVVESASQEDVQDTILPTLSEEE
AIFIERLVSDLKFPNLLPPNPVIKILIAFCKNDPVFEALVNASHRLSLEPTFVKSAESAI
DAFQNPSSGGHHIIIVDARYPRTIEAEALGRSIRNSKGSQHTTMVAVVKKSVFEKDDTAV
ISLLDVGYNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQALYTALHRSREAVIITD
DTLRAQYANRASERVLNMKLDEIVGRSLSDLVTADISNILSHTSRYKDYDGYLTTRRKSQ
ESSQIHVRAVPVSCIGRNPTHLVLILESSSSALVSTNAIGEALQTLPQGKEVPRGSLHSI
RRGSFDVRSIASDGLRRTSLAKLSSLPLEAPITKVLSLLAQVQENCSLDEAKLLDRVMEF
LKREGLYSPQMKEIRTEDPVATDLIGALLTQGPTNILSSRRSSNDSIIRGGGRPSTGSIV
FNKTKESSQLSDLLQTALDWDFEIFKLEDLTEKRPLVCLGLELFRRFDVYNTFNCDEMTF
KLWLIEMEKHYHSENTYHNSTHAADVMQATAVYLQQLSNRELKIMDRMDEATALIAAATH
DIDHPGRSSAFLCNSDNTLALLYNDICVLESHHAATTFRLTLGDDKINIFKHLDRDMYKL
ARSIIVDMILATEMTRHFEHLAKFVSVFGTDVESKDPLPPDNDDNQILVRRMLIKCADVS
NPTRPLKFCVEWARRIAEEYFMQTDEEKRKNLPIVMPMFDRTTCSISKSQIGFIEYIIHD
MMDAWNSFIEMPEIIRYMEFNYSQWKLFEEQGINTLSDIKRKQMSLTEDTASSISLEEKF
>A0A0J2E087|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPGRHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A777WN93|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYLHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCRWLDQHSL
RNAGELDNVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A853SVB2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Janthinobacterium sp. HH102|TrEMBL
MRLLILSDLHLEVWGEDTPAIDLAASRPDVVILAGDIDTGSNAIAWAARTFGALPVLYVH
GNHEGYGHQLERMQDAVRDACTSANAQGANIRLLDGDAVTLDGVRFLGVTLWTDFLLFGA
ERRDEALSAAQSYMPDYKRISTGGDTPRLLCASDTAQLHAQHRSWLEQQLAQPFEGKTVV
ITHMAPSMLSVEEQYATNLGSPAFASQLDELVTQADLWVHGHMHASLDYRVQGCRVVCNP
CGYKRPDGTPENDRYDSGFIVDLAGTV
>A0A739DT10|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar 4,[5],12:b:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A1Q9HCH0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio panuliri|TrEMBL
MKVTSNTKVKDTIKLLQITDTHLFEAEDGSLLSVCTNESFKAVVEAVTDESFQFDAILAT
GDISQDHSDASYRRFAEGIKPLKQDCFWLPGNHDYKPSMNSVMPSQQIMQVEHALLGEHW
QMVLLDSQVEGVPHGRLSQSQLALLESKLAQYPERHTLVLLHHHPLLVGSAWLDQHTLKD
AEQFWQVVERHSNVRAILCGHVHQDMQKVHSGATVIATPSTCVQFKPNSDDFALDSCSPG
WRELELHADGSFDTRVKRLEDGLFAPNFDSNGY
>A0A0T7EBU2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio coralliirubri|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPHGQFLPDFKAAGY
>A0A2L1VKW2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter nosocomialis|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIQQILKQHPEADAIIHT
GDLAQAPTPITYKRYINFMQTLGLPFFHTLGNHDNVDHFPLHNENHQEPVVVGLGNWRII
MLNSAVKGKVDGHLSLEQLENLENLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFKNVKALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLNNDGTFETKVFRLENFETHINTDISGY
>A0A2X2E9J5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Raoultella planticola|TrEMBL
MESLLNLPLAGETRVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRPCDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQILLLDSQVFGVPHGELSDFQLEWLEQRLAEEPERYTLLLLHHHPLPSGCSWLDQHSL
RNAGALDRALAAFPRVRHLLCGHIHQELDLNWNGRRMMATPSTCVQFKPHCANFTLDTIS
PGWRWLELHADGTLTTEVCRLNGVKFHPDIASEGY
>E0VRW3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pediculus humanus subsp. corporis|TrEMBL
MGWGRGGKFFFLFLKILIGFPKDDPILENLIQASEKLGYECTTCNCPETIVDVYSQVGHD
IVILDNRNVKYLDAPAICRKIRRSKWNRKSVVVAIVKKSYFEDSYCLPLLNAGFNRCLIE
TPNVGILINELTEIEHGEVRPRISVTNANALYIALSKCKDLIQVTDDSFNLLFVNKATEN
FLGIKNEDVKGKPISEIHQTTDHHNQMTYLLSRGKEWEGSVTCIRKTGEPIPLICRVVSS
SLNSRYLKIIIEVIFPPNITNYIFIEEQPVSETGITFKDQPPRGSLHSIRKGSYDVKSLA
SDSGQSIRRQSLAKLNSLPIEAPITKIITLLYSVHEQSSGHVQLQIEKVLDILRSTELYS
PQLKENRIRMDDPITADLISALLSQGNAATSTTRRSSNDSANIKGSGTSRPSLPSINAPG
QLSSVLEQSLDWEFDIFKLEELSNQRPLVWLGMNLLCHFNVQDTLGCEEKTLMNWLTVVE
MHYHSINTYHNSTHAADVMQASACYLKREKLSELLDPLDMACVLIAACCHDIDHPGKSSI
FLCNSNHDLAILYNDQSVLESHHAAMTFKLTLADDRVNIFKGLERDTYKVARQSIIDMIL
ATEMTRHFEHLAKFVNVFTKPDPKEENGGGSVGDLLDVGNFQTQENIALAKRMLIKCADV
SNPTRPLKQCVEWAKRIAEEYFNQTDEEKANGLPVVMPMFDRSSCSIPKSQIGFVDFIIN
DMMEAWDSFIELPEILYYLRSNYQYWKEKEEQGVTSINELYPFNNNRIELLKELDESKAD
>A0A0D6ICX2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella typhimurium|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A3Q9M930|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Moero|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A3V4B9C9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella virchow|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A8B5SAE1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter bereziniae|TrEMBL
MQSKILQQTDKDKVIIQITDTHLMDKPDAKFVGINPEESFHAVMEDVQQRFPNADLILHT
GDLAQAAYPETYARYLNYMRGFGIDFYHIPGNHDNLSFFPFHLPEPEPTVIELDQWCIIL
LNSTVSGRTDGKIQPEQLVRLKQRLEQLRDKFVIVACHHNPFEMHSKWLDQHKLKNADEL
KAVLEPFNNIKLLLHGHVHQESYNEWNGIQFISTPATCVQFKPLSQEFSFDPIAPGYRCL
HLKANGEFETYVHRLDHFNVTINEEISGY
>A0A7T7R787|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. CS-2|TrEMBL
MTLYQPNEDQQDWTIIQISDTHLMDQDDLEFVEMNPEQSFHAVMQQIQQQYPSTDAIIHT
GDLAQVPVKQTYTRYLSYMQNLGIPFYQIPGNHDDIDLFPFYQHKNQVHAIHFGRWSVLL
LNTAVDGRIDGRIEPEQLQQLDQLLAELQQQFVIVACHHHPFAMQSKWIDQHKLKNPENL
TAVLARHSHVKAVIFGHVHQDSCHEWQHIRFFSTPSTCVQFKPFSENFALDDQAPGFRVL
HLKANGELETRIQRVQTVRQQINSEISGY
>A0A5C5R3K9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas mandelii|TrEMBL
MPSVSTLTTADSALLVQLSDSHLFAEADGKLLGMNTRDSLQKVIELVRLQQPQIDLIVAS
GDLSQDGTLESYQLFRDLTRQLDAPARWIPGNHDEPRIMAEAAVQSALLEPVVDVGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCFHHHPVLIGCLWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEVDQVRKGVRLIASPSTCIQFEPGSDDFKVGEQAPGYR
WLRLLPDGQIETGVERVTGFDFQVDFGSNGY
>A0A346S477|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter sp. Arc7-DN-1|TrEMBL
MTIKEETRPLRVLQLTDPHLMARADGDLLGVKTRESLQAVIAEVLKVHGQPDLILATGDL
AQDGSVDAYRVFGESLEVFSCPSTWIAGNHDRIENLERVAAEFDANQRHVIQGGWQFVML
DSSVPGKVFGALADSELEFLAQALEQHPDLPAVVALHHHPVDIGSDWMEKIGLTNRDAFW
RVVDRFPQVKIVLWGHIHQEHERERHGVQLMATPSTCIQFTSGSSKFAVEDLPPGYRWFE
FHDTGDFMTEVRRATDFQFELDQNSTGY
>A0A8F6E7V8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas tolaasii|TrEMBL
MPSVSTVNPDAPALLVQLSDSHLFAKADGALLGMNTRESLQRVIERVREQQPQIDLVLAT
GDLSQDGTLASYQQFRDLTRQIDAPARWIPGNHDEPQIMAHAAVHSDLLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPNRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERVQNFAFTIDYGSNGY
>A0A6B1Y433|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas aeruginosa|TrEMBL
MSRHSNTPATDASVLLVQLSDSHLFAEDGARLLGMDTAHSLEKVVERVAREQPRIDLILA
TGDVSQDGSLDSYTRFRRLSAPLDAPLRWFAGNHDEREPMQRATEGSDLLEQVVDVGNWR
VVLLDSSIPGAVPGYLEEDQLELLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGY
RWLRLHDDGSLETGISRVDDVVFEVDYDTAGY
>A0A836ZBR4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli 2-460-02_S1_C1|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A6G6NN63|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas veronii|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHPYEVILAT
GDLSQDHSPESYQRFASMMAPLGRPIYWLPGNHDDSPLMTEQLHAAGISESKQLVGDHWQ
VILLDTQVRGKPHGMIGDHQLEALDRALRQYPDRHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLILYPDGRVASEVWRLPVGLFVPDPNATGY
>A0A1V3H0G6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salinivibrio sharmensis|TrEMBL
MQSCQIDNADGDCIRLLQITDTHLFASEQGSLLGVNTLQSYHAVLDAISATDPTFDAIIA
TGDLSQDHSALSYRRFVDGIARWEQPCFWLPGNHDYQPEMSAVLQSNTLRSCSQVLLGEH
WQMVLLDSQVAGVPHGELSQAQLNLLDTHLSAHPERHALVLLHHHPLDAGSTWLDQHKLA
NREAFWQVMSRHPQAKIVVCGHIHQALDVRYQGARVIAAPSTCIQFMPDSHDFALDNQNP
GWRWLELYADGRVETQVARVTGXHFRPDFDSSGY
>A0A068QWB9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus doucetiae|TrEMBL
MESLLEIPVAEGATARILQITDTHLFANKGDSLLGVNTYRSYHAVLDAILAQNPAIDLIV
ATGDLVQDQTINAYQHFAEGIARLPAPCVWLPGNHDYQPAMVDTLAAAGISPSKQIFIGQ
HWQLIMLDSQVQGVPHGELTDYQLEWMKKCLNEHSERQTIIMLHHHPLPSGCTWLDQHSL
RNAPELSECLKGKTQVKAILCGHIHQEVDEMWHGIRVMATPSTCVQFKPHCTNFMLDTVA
PGWRYLELAVTGNHQEAKLQTQVHRLKSNEFCPDLDSDGY
>A0A1S8CLV1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia oryzae|TrEMBL
MESLFQLPVASGATVRILQITDTHLFAGKSETLLGINTYSSYHAVLDAIIAQQRASDLIV
ATGDLAQDHSLAAYRHFAEGITRLPAPCAWLPGNHDFQPAMVDALAAAGIAPSKHILLGD
RWQVLLLDSQVFGVPHGELSDYQLEWMERCLIAFPERYTLLLLHHHPLASGCTWLDQHSL
RNSHMLDAVLAHYPKVNTLLCGHIHQELDLDWQGRRVLASPSTCVQFKPHCTNFTIDEVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A369YR47|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus parainfluenzae|TrEMBL
MNNRFEYESAIEIVKLLQITDPHLFKDTSKDLLGINTHESFSQVLKEIQAESFDYDVVLA
TGDLVQDSSDEGYLRFVEMVKPLNKSVFWLPGNHDFQPKMVEHLSQPPINASKHLLLGKH
WQVILLDSQVSGVPHGELSAYQLDWLKTKLAENPARHSLVVLHHHLLPTNSAWLDQHNLR
NAHEFSEVLAQFNNVKGILYGHIHQEVDGYWQGYQTMATPATCIQFKPDSNHFALDTLQP
GWREIELHLDGRIETRVKRIKQKTFLPNMEEEGY
>A0A369YSP1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus parainfluenzae|TrEMBL
MSNTFECEPASEIVKLLQITDPHLFKDTSKDLLGINTHESFSQVLKEIQAESFDYDVVLA
TGDLVQDSSDEGYLRFVEMVKPLNKSVFWLPGNHDFQPKMVEHLSQPPINASKHLLLGKH
WQVILLDSQVSGVPHGELSTYQLDWLKTKLAENPARHSLVVLHHHLLPTNSAWLDQHNLR
NAHEFSVVLAQFNNVKGILYGHIHQEVDGYWQGYQTMATPATCIQFKPDSNHFALDTLQP
GWREIELHPDGRIETRVKRIKQKTFLPNMEEEGY
>A0A3S5EXE0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus parainfluenzae|TrEMBL
MSNTFEYEPASEIVKLLQITDPHLFKDTSKELLGINTHESFSQVLKEIQAESFNYDVVLA
TGDLVQDSSDEGYLRFVEMVKPLNKSVFWLPGNHDFQPKMVEHLSQSPINASKHLLLGKH
WQVILLDSQVSGVPHGELSAYQLDWLKMKLAENPARYSLVVLHHHLLPTNSAWLDQHNLR
NAHEFSEVLAQFNNVKGILYGHIHQEVDGYWQGYQTMATPATCIQFKPDSNHFALDTLQP
GWREIELYPDGRIETRVKRIKHKTFLPNMEEEGY
>A0A2H5VT92|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR09|TrEMBL
MHAVTYITRHRRWPARLGWGGEGLYSRFRWHRERSLPLVRRVLLVHPRLPEAFDGLTVAQ
VSDVHAGQFMTPDRLEKVRALVCRLAPDMIVFTGDQLDRRPVDAELFVQAFAGLSAPLGV
YGILGNHDYLAGRELAVAALEAAGITPLVNEAALVQRRGASLLLAGVDDLDAPRPFGPDF
SVLRTGNGFFKLLLCHQPRLWPEAIRHGADLTLSGHTHGGQISPIGERFSVARLATRFVA
GSYVSGSHLLYVSRGVGVGAVPLRVGTLPEVDLITLHRGQPAASL
>A0A1W4UA72|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila ficusphila|TrEMBL
MIISSQPNLVGSATTTTTTTNAHMSEESVPSTCNCGGGGVAVAMAVGGGVGGVVALGARQ
SPVAEPTTTTATATTTVTATTILKTPTSTAAGRDSLTRPASESELNVGTGTSGTSSSGGG
NSRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLVFHKSDSICEAV
TAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSTKNLDAEHIARTIRHTH
GHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNV
MSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSDLST
ISEQCKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQMDFIAT
LPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQEN
CSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSI
IRTGSSTRTASIVPAKMKSNPIIMELLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRF
DVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDMMMMDR
MEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLGDDKI
NIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPRDHNSQTDEETSIL
MRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRATCSIPK
SQIGFIEYIIQDMIHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLAEIMAKQPPVGK
MANSK
>A0A6I5RVT9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas laurentiana|TrEMBL
MLPLSTPASDAPVLLVQLSDSHLFADEGSTLLGMNTGDSLQRVIGQVLDEQPRIDLVLAT
GDLSQDGTQASYERFRQMSERIPAPVRWLAGNHDEPLPMAQAAQGSDVLEPVMDIGAWRV
ILLNSAVSGAVPGLLADDQLQLLEWALATAPERHHLVCLHHHPVSIACAWMAPIGLRNGD
ALFAVLERYPQVRAVLWGHVHQEWDEQRGDIRLLASPSTCIQFEPGSEDFTVGEQAPGYR
WLRLYANGQIDTGVSRVSDFAYTVDYGSNGY
>A0A1D7Z0Z3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium wasabiae CFBP 3304|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKVRQEAFDLIV
ATGDLAQDHTLQAYHHFSSGIAQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLQGQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSAVLDRYPKVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPDGCLETEVYRLSGSEFLPDMNSDGY
>D4E0S6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia odorifera DSM 4582|TrEMBL
MESLLKLPVASGAKVRILQITDTHLFAGENETLLGINTYRSYHAVLDAICAQQREYDLIV
ATGDLAQDHSLEAYRHFADGIAQLPAPCVWLPGNHDFQPAMVDALAAAGISPSKQVLLGD
GWQVILLDSQVFGVPHGELSEYQLEWLERCLQAYPERATLLLLHHHPLPSGCTWLDQHSL
RNPHMLDVVLQRYPKVNTLLCGHIHQDLDLAWHGRRVLASPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A8G2LBU0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia sp. JKS296|TrEMBL
MESLFKLPVASGAAVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAIQAQRRDVDLIV
ATGDLAQDHSQEAYRHFAAGIAQLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLLGD
NWQVLMLDSQVFGVPHGELSEYQLEWMERCLQAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAILLRYPKVNTVVCGHIHQDLDLEWQGRRLLATPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A418XL85|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas cavernicola|TrEMBL
MPNSSTLAADSSVLLVQLSDSHLLADAHGKLLGMDTQDSLQRVIERVLEEQPQIDLVLAS
GDISQDGSLESYARFRQLTSVIAAPARWFPGNHDELPAMRSASVESELLEPVVDLGGWRI
TLLDSSIPGAVPGYLDEQQLGLLARSLSEAPERHHLICLHHHPVSIGCRWMEPIGLRNPD
ELFAVLDRFPQVRALLWGHIHQEFDQQRNGVRLLASPSTCVQFAPGSEEFQVDQEAPGYR
WLRLHADGQLETGVSRVTGIPFVVDYSVKGY
>A0A6S7DV01|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter piechaudii|TrEMBL
MLIAQITDLHMRTPGDKAYGVIDPAAFLAPAVLALNALTPRPDCVLITGDLTDLGRPHEY
QVLREHLQALEIPYFLLPGNHDDRAQLRAAFPDHTYLQGAGPFIQYAIETYPLRLLALDT
VVPMKSHGELCQDRLDWLAARLAEQPDRPTLVLMHHPPFLTGIEHMDAIGLLAGAPELER
IVSRFPNVERVLCGHLHRTIFQRFGGTIASTCPGTAHQLALELGPRPTLQYIMEPPGYQL
HWWQGTSLVTHHAVLGDYPGPYPFA
>A0A140N5S6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli (strain B / BL21-DE3)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPGRHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A844WK89|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gilliamella sp. Pas-s27|TrEMBL
MESFLKLPIRNRNYGRILHITDTHLFSDDDSSLLGVHSNASFLSVINEIERSNKKFDLIV
ASGDFVQDGSKKAYARFAKQINKFNTPCVWLAGNHDNYAYMQDVFDNYQLADNKIVQLGS
KWLIVLLNSQVVGQAYGFLPESELEFLQNALTKYSSRYVLAFLHHHPISSGCHWLDQHIL
KNSGQLEQMIQQHPNIKGIGWGHIHQKQDYIWHHCNAFSTPSTCFQFKPECYDFQLSSDD
APGWREIKLNADGSIESDVYRLTNNQFLPDISQNGY
>A0A5B0X0U0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus heterorhabditis|TrEMBL
MESLFELPVVEGTTAKILQITDTHLFAGKEDTLLGINTYRSYHSVLDAILAQNTEIDLIV
ATGDLAQDQTLEAYQHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGISPSKQILVGK
YWQLLMLDSQVQGVPHGELSEYQLEWMKKCLDEYPERYAVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLRGYSQVKAMLCGHIHQEIDLDWNSIRMMATPSTCVQFKPHCTNFMLDTVA
PGWRYLELSVNDKGEFGLTTQVYRLESNEFCPDLESDGY
>A0A6P8WUN2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila albomicans|TrEMBL
MSLNVSKCCTGTSGTSSSGGGRPGHRKSSLALALTPEDEPMDVYTRNLMDLKYPTVLPPN
PQLKALLVFHKSDSICEVVTLACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDA
RSTKGLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDALIALLDAGVNRCIAETTNLA
MCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMR
LDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMHVRVVPVACIGSAP
THLIFNFDIPGGGMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSL
PLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIG
ALLTGPSVYSSRRSSNDSIIRTGNSTRTAIVPAKMKANPIVMELLEESLSWDFDIFKLEE
ITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADVMQA
TGAFITQLTNREMVMDRMDEATALIAAAAHDVDHPGRSSAFLSNSNNPLAILYNDLTVLE
NHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGS
EVEPRELVQSEEETSILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYFMQTDEEKQRH
LPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWDSFIDMPQLITCMQINYSQWKKYDEQ
GVNTLADIMAKQPPVGNKPSNSK
>A0A5J4PI62|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
VLVQVIGNILPLSLATIMYRVGTSWFFIFIYLLIIFLLLELVRVTGLCPVAKFMHGSWYG
LGVLAGVLTLILTWGYIVYLNKARVELSLTVNKEVGTERSLKIVAISDLHLGYGIGRKEF
EGWIKLINKENPDIVLIAGDAIDNSIRPLYERGIAESFKQINTKYGIYASPGNHEYITGI
SSSLAFLKEAGIMVLRDSIAFINDTFYIVGRDDRANSARKSLEELTDTLDKSKLLILLDH
QPYNLEQAERNGIDLQISGHTHYGQIFPISLITEMMYEKAHGYLKKGDSHIYVSSGLGLW
GG
>A0A5J4SJ37|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MTAFLLCTFVNADSPRFAVISDIHFGSKAEKGPTVKVPQALKNILGKERLDALFIVGDLT
NNGKEEEYDQLKSVFDDKTIVPEGIAVYSLSFSIYFR
>A0A558E581|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp|TrEMBL
MPGASLTVEDSVLLVQLTDSHLFAEADGKLLGMNTCDSLEQVVELAIDEQPRIDLILATG
DLSQDGSVASYQRFRRLAERIEAPARWCPGNHDELAAMREACRGSALMEPVLEIGGWRVV
MLDTLVAGSVFGMLRNDQLELLERALSEAPDHHHLICLHHHPVSIGSRWMDTIGLRNPEA
LFEVLDRHRNVRALLWGHIHQEFDHWRNGVRLLASPSTGVQFAPQSEDFQVDSVAPGYRW
LRLYVDGQLETGVSRVSGIEFEIDYSVKGY
>A0A655Q290|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cholerae|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFAAEDGSLLSVNTADSFAAVVAAIGEEQVEFDAILATG
DISQDHTPESYQRFVRGIQPLKKACYWLPGNHDYKPSMHGVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEYPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRIHLGARVMATPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A5W8M9Q4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Hofit|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A7W2V644|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. RHBSTW-01064|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLNAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLLESGISPAKCVFAGD
HWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPARNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLVNFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGNLTTEVCRLSGAKFRPDTASEGY
>A0A2Z3YR13|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Corynebacterium provencense|TrEMBL
MTDPFWTVSDLHLGHRLVAGLRGFADTDDHDRVILDNLREVPSGATLVCLGDISVRKDAY
ALDRLSALKAEKDLTLWLVPGNHDRVHPMFGWDSVAEWTPRYRKVFDVIAPDLQVRIGRW
SVLLTHIPRASGKDSVPDPHQTPYLARWAGREGFDCTVHGHTHSPVPVTRKHVNLSLEAT
GLAPVSPEKLEELVTQAVRFRG
>A0A482PIN7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter rodentium|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIHADGQEYDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKCVMAGE
HWQILLLDSQVFGVPHGELSEFQLEWLENKLAAAPERYTLLLLHHHPMPAGCSWLDQHSL
RNAAELDSVLANYPRVTHLLCGHIHQDLDVDWNGRRLLATPSTCVQFKPHCANFTLDTIS
PGWRTLELFADGTLQTDICRLQGDAFRPDTDSEGY
>A0A3P5Y5Q3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptococcus canis|TrEMBL
MSDLHLDLNHFGPFERNTLIELLKHEKIDHLHLAGDMANHFYQDTEPFLTTLANEVTVTF
NLGNHDMLDVTEADIETLDFKTYALNPSTTLLAFHGWYDYGFSEEMAGADYVAFKNRFWF
DRRLKRPLTDPELTKEICQTLEKTLAALSDQTLIVAMHFVPHSIFTLKHPKVKAFNAFLG
SPAFHDIFRRYGVKEVVFGHNHKRFSPQTIDGVTYQSRPLGYTKEWQLTRAFIQKNPPTT
IRGNWTPNKAYHAIKDLATFKAYQTKHLATELRDAMIIFDIDDERTIP
>A0A1S6IM15|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Jeotgalibaca dankookensis|TrEMBL
MKLRKKLVHTAATGASLAAYLYSQNTRFQTTHYRIPIHQLAVENVGIKVAQLSDLHFPYI
KINQNKLIQKLVQEQPDLIFLTGDQMDAAEPERWYELHTFLKRVSAIAPSYAIMGNHDHV
NPNNEAIYQGTGVTFLNNQAESITLPDRLPLLIMGVSEPSFVAKRKAKNLIKKVYVRPEW
QEQTKLLLAHRPELFEKYQADAEKAPDLTFSGHAHGGQVRIKGIGGLFAPGQGRLPKHTA
GVFSLASDTHKKLVVSRGLGPSHFPLRVNNRPELVIVTLVRE
>A0A8G0E7F8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Minnesota|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A3N4WEJ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Frederiksenia canicola|TrEMBL
MQEPYHFPDLASIRILQITDPHLFTNEDGQLLGVPTIRSFEAVLNAILREPFQYDFILAT
GDLVQDHNREAYHRFANMVKPLAKPIFWVEGNHDLQPQMSNALSMYAQIQPHKQVLAGQK
WQVILLDSHLPEQPKGELSQAQLNFLAEKLAMYPDRYALIALHHNILPTNSAWLDQHSLA
NADQLADVLSDFPMVKGILHGHIHQEVDQMWHGYRVLATPSTCIQFKPNCDEFTLDPIPQ
GWRELILHPDGSIETQVKRLDCNDFLPNFKAWGY
>A0A846EYT7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Okeania sp. SIO1H5|TrEMBL
MIFQPSVLVAQITDTHLFADSIQGKMYGVPTERSFVKVLEKLKQLQPQPDVLLLTGDLSQ
DETSQSYQRLASLLSPLNIPTYWIAGNHDNLPTMERVLSSAPISAKKSFEMGGWNFFLLN
TNVPGCVYGEISPESLEWLEYNIKMTGNKPVLIALHHPPVKINSEWMDKILLHNPENFLS
IINRYPQVKIVLSGHIHQEFAKEINGIHYLSTPSTCIQFEPGNYKFFLDKQPPGLRLLTL
YPDGNYTTKIERINYIYECDMAASGY
>B1EGE2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia albertii (strain TW07627)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYLHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCRWLDQHSL
RNAGELDNVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A348D867|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Metakosakonia sp. MRY16-398|TrEMBL
MESLLNLPLAGGARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIQAQQRECDLIV
ATGDLAQDQTAAAYQHFAEGIARFGAPCVWLPGNHDFQPAMYTALQEAGISSSKRVITGD
NWQILLLDSQVFGVPHGELSEFQLDWLEKKLSASPERHTLLLLHHHPLPSGCSWLDQHSL
RNAAELDNVLARFPHVRYLLCGHIHQELDLNWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLYPDGSLQTEVCRLQCTRFNPDTASEGY
>A0A5A9D267|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter braakii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRAKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A6J5EBH4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia humisilvae|TrEMBL
MRIRVLSDLHLECDEPDVIPHADADLVVLAGDIHNHAQGLRWAAQTFDGAVPVVYVPGNH
EYYDGEFGALEAAMQDAARSVDNVHFLNNAALVDPQGRWRVLGTTLWTDFELYGAQPEER
AASMAATQRAMLDYRGLIQVTWGDPAKERASTPRAATPLERGTPRDFTPADSLALHTRSL
AWLTRELAQPFTGKTIVVTHHAPHRRSLAERYTDDRVSAGFVSDLPALVRAPVALWIHGH
THTGFDYVENGTRVVCNPRGYFDWRARKLENEQFSWNKVVEI
>A0A7X5S2C5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter agglomerans|TrEMBL
MDSLLTLPAANGSEIRILQITDTHLFAGKHESLLGVNTWSSYKAVLDAIIAQHRDYDLII
ATGDLAQDHSIEAYQHFAEGISRLPRPCVWLPGNHDFQPAMFDTLAAAHINAHKQVLVGE
QWQIVLLDSQVSGVPHGMLSDYQLEWLDNALARYPQRHTLVLLHHHPLASGCTWLDQHSL
RNSHQLDAVLQHYPLARTLVCGHIHQELDVEWHGRRVLATPSTCVQFKPHCTSFTIDTVA
PGWRWFTLYPDGGLETEVNRLDTDAFRPDLDSEGY
>A0A7X2MS98|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter agglomerans|TrEMBL
NHDFQPAMFDTLAAAHINAHKQVLVGEQWQIVLLDSQVSGVPHGMLSDYQLEWLDNALAR
YPQRHTLVLLHHHPLASGCTWLDQHSLRNSHQLDAVLQHYPLARTLVCGHIHQELDLEWH
GRRVLATPSTCVQFKPHCTSFTIDTVAPGWRWFTLYPDGGLETEVNRLDTDAFRPDLDSE
GY
>A0A2J8NHF7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pan troglodytes|TrEMBL
METLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTF
LDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLA
KELEDLNKWGLNIFNVAGYSHNR
>A0A2S8QSZ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus luminescens|TrEMBL
MESQFELPVVEGTTAKILQITDTHLFASKEDTLLGINTYRSYQAVLDAILKQNADIDLIV
ATGDLVQDQSLEAYRHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGK
HWQLLMLDSQVQGVPHGELSEYQLEWMKNCLDRHPERYAVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQSYSRVKAMLCGHIHQEMDLDWNGIRMMATPSTCLQFKPHCTNFMLDTVA
PGWRYLELSVADNGEFGLTTQVYRLASNEFCPDLDSDGY
>A0A7J0B0Y0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alistipes sp|TrEMBL
MKLLHLTSLLAVALLAIPGGATARQPKFGDDGKFKIIQFTDAHVRADKPDEMAKTIDRLV
RTIDAEAPDMIVFTGDVVTGRPAAKAWRAILDPVARRNIPFVVVLGNHDREQDLREEQIA
QLVTAYPNSLNAAEDGRLSDIAVPIISGDSERTAAVLYCIDSNDYSTIEGLKKYGWIRFE
QIEHYRRTSREYTLANGGKPLPSYAFFHIPLPEYAEACTADPKAVRGIRREAECAPPINT
GMFAAMKECGDIVATFVGHDHDNDYIIPHHGIALVYGRYSGDNTVYNHLRRGVRIIELTE
GERDFTTWIRQSDGEKIDHVRFDARSSKLREAKE
>A0A5H9X599|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Ajiobo|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFCAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A6C7IF11|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella typhimurium (strain D23580)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A836JMN2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudoatta argentina|TrEMBL
MGCKISIPKCMKDKVEQEKSISSETSSSSIVISDTTEPDRDEDSLYFAFDTFKSHNFITE
EDDQKVEQHKTDAFEIVAEKNEKTPFEDNTNDDYDENGDYLTVKGPQDFSNYLLTTNVPS
IVKILLVFSKDDQQMDILSNTARRLGWSVSIAKDAEKALELFQNRAHELVIIDHRAHHAA
DGDAICRTIRSSPVYHSSVIIALVKKSYFMVDEKGRIVALDLLKTGFDRALMECSHEGIL
INELVGIYTSSLLPKTQLAAAHALYLALDRCRDMVHVTNDKNIVQFLNKVSEKLLGYNVE
EIMGRNLSEIVSYENFPLMEQQLNKGREFEGNMNCKRKNNQMIMINCRIIPFCITLKKPS
HYIYVYDTTYLSENSAPISPISSPLHPPLKTITTNARKFSDVRSGSISEDKGRRRSSLQK
LHTLQLEAPITKVITLLSNAVTDTTNPETAAQIDKAIDILKTTELYIPHLKEDRAMCCDP
VATDLVGALLSSPRTTWESRRSSSDSARLSAIKAITSPTNSRVQVKNFRGPQEIMEILDK
SLDWDFEIFKLEVLTEGRPLVFLGLTIMNLYRVPATIHCDERTLQNWLAIIEHNYNAENS
YHNSTHAADVLQATARFMQSKRLKEILEPLDEVAALVAAATHDIDHPGRSSQFLCNANSR
LAILYNDLSVLESHHAALTFKLSLSDDSVNIFKNMERDAYKLLRQNVIDMILATEMTKHF
EHLAKFMNVCSARIGDGQETYSDSLDMTVVLQPDNVILIKRMMIKCADISNPTRPLKCCV
EWAKRIAEEYFNQTDEEKKLKMPVVMPMFDRLTCSIPKSQIGFVDYIINDMIEAWDVFID
MPEIVGYMRYNYEKWKEYNMSIVPLVFRNWWDDFDRPVSRLLDQHFGIGLHRDDLISSLS
GLGLDRPSVRFGNRYYRPWGNVTRQNSSGTSTIQLDNDNFQVILDVQQFSPDEITVKTSD
NHVVVEAKHEEKQDEHGYISRHFVRRYVLPPSHDLVNITSTLSSDGVLTVTAPKKNVTPA
GTERVISVVQTGIPAAKPVPVETTATTTTTTTN
>A0A8I0DBX4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella quasipneumoniae|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVFLGD
HWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDFDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A3N2QZU0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter sp. R17|TrEMBL
MSDKPSSAPLRILQITDPHLMADPDGVLLGMNTRESLEAVLALAAEAEDGAPDLVLASGD
ISQDGSEAAYRLFQRLMSGFTCPVIWFPGNHDDAAAMRKVIAGTGADERRVLAGGWQVIC
LDSSVPGQVHGQLADSELDFLRDCLAEYPDTPTLVTFHHHPVDIDCSWMADIGLVNRDAL
YRVLAGQPQVRGLLWGHIHQAWDDDRDGLRLMATPSTCIQFAPGSTDFSLDDKAPGYRWL
ALYPDGSLASHVRRAEDYAYTVDLNSHGY
>A0A5R9QHQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas nosocomialis|TrEMBL
MSSTPTTAADSVLLVQLTDSHLFADQGGKLLGMDTGYSLDRVIDLVLDEQDDIDLILASG
DLSQDGSVSSYLRFQALTSRIPAPVRWYPGNHDEADAMRAVVADSDLMDPVLDLGRWRII
MLDSQIPGAVAGYLADEQLELLERSLREAPDRHHLVSFHHHPVEIGSRWMDTIGLRNAGA
LFEVLDRYPQVRAVLWGHIHQEYDQWRNGVRLLASPSTGIQFAPGSDDFLVDTRSPGYRW
LRLHDDGQLETGVSRVSGIDFKVDYSVKGY
>A0A6L5QWB2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kangiella sp. HZ709|TrEMBL
MSVLSKLEPAIIKSSETVDTLELIQISDPHLFADESGSLLGVNTRESFLATLDLIQANHL
YIDLIIVTGDISQDLSAESYEFFAQAMKVFNCPIYCLAGNHDEVDALESLAEAGHIKTNK
QLDIKNWQILLAHSQVKGKVHGLISSDEMHWIQQQLNTNDSNALVFTHHHPVYSNADWID
DIGIKNCEEFTAMLSEFKQVKACGFGHIHQDLSVTQQNIDYYSAPSTCIQFKQNSSEFAV
SEELPGYRIYHCYPSGKVETQVIRVNDFKLSLDMTATGY
>A0A233HW70|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. V03_P4A6T147|TrEMBL
MNVSPTLDNSDSIKLLQITDTHLFAPDDGSLLSVNTVDSFHAVVAEICAQHVEFDAILAT
GDISQDHSAESYLRFSRGISSLEKTCFWLPGNHDFKPNMGAVFPSEQIQQSEHVLLGEHW
QMVMLDSQVVGVPHGRLSDQQLALLDEKLSTYHQRHTLIVLHHHPLLVGSAWLDQHSLKD
SDAFWNIVTQHRNVKAVLCGHVHQNMDKLHHGVRVMATPSTCVQFKPNSDDFALDRTSPG
WRELTLSADGQIETQVKRLANGAFQPDFNANGY
>A0A829QUG9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia alcalifaciens 205/92|TrEMBL
MDSQLKVTANNPNVIRILQVTDTHLFADTENTLLGINTYRSYQAVLDAIAEQNLPVDLIV
ATGDLVQDQSPKAYQHFAAGIERIPAPCVWLPGNHDYPPAMVGTLKIAGISSAKQVFIGD
DWQILMLDSQLQDVAHGELSEQQLEWMQQCLDEQPTRTTLIMLHHHPLPSGCTWLDQHSL
RNSHILADYLKNYPNVKAMLCGHIHQEMDENWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELTVNENGEKVIETQVHRLNTQAFSPDFDSDGY
>A0A5A5RG43|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcystis aeruginosa NIES-2519|TrEMBL
MQRRKFLLISGSLGGFSLVACAHQILQPVTSKNPPESPVKQAQKAKKVKIIVISDLNSQY
GSTTYDPEIDRAIPLIINHKPDLVLCGGDMVAGQKSSLTEAAINAMWSAFDHHIAAPLRA
AKIPFAFTIGNHDASGALSTGKFIYAKERKLAQDYWQNPQHNTSLNFIDKTGFPFYYTFT
QNGIFYLVWDASTHLISREQLNWAAKNLSSSDAKNAKMRLVIGHLPLYGIAVGRNRPGDY
LADAEQLRAFLESHQVHTYISGHAHAYYPGKRGQLQLLHAGALGSGPRRLLNSEQAPRKT
LTIVDINPNQQETVYTTYDMKTQEAIDITSLPPLIMAPNGQVLRRDIPSVN
>A0A7Y7YMK0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cedecea sp. P7760|TrEMBL
MESLLTLPVADGGRIRILQITDTHLFAGKNETLLGINTWKSYQAVLAAIHAEQRTCDLLV
ATGDLAQDHSVEAYQHFAEGISSIAAPCVWLPGNHDFQPAMFGALQEAGISPAKRVYIGD
HWQILLLDSQVFGVPHGELSDYQLEWLERQLAAAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAAALDAVLRPWPQVKTLLCGHIHQELDLDWNGRRMLATPSTCVQFKPHCANFTLDTIE
PGWRWLDLYPDGSLTTEVCRLQTGKFSPDTASEGY
>A0A2R8A8P3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pontivivens insulae|TrEMBL
MAPFRFHTADLDALESGALYWAAERLLCVSDLHLGKSERIARRGGALLPPYDTRETLDRL
SAEIARHDPATVICLGDSFDDLDALDRLAEAARRHLLTLMAGRRWIWIEGNHDPGPTDLG
GEHLFEASINSLTFRHVAEPGTPPGEVSGHYHPKASLTLRGRRVSSACFLSDATRLILPA
FGAYTGGLKVSDPAVSNLMMPEACVRLTRAPQHAIPLRLVA
>A0A0J8VM45|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Franconibacter pulveris|TrEMBL
MESLLNLPVAGGASVRILQITDTHLFAGKDETLLGIKTWESYQAVLAAIHEQQRPCDLIV
ATGDLAQDHSPEAYQHFASGISSISAPCVWLPGNHDFQPAMYSALQEAGISPAKRVMVGE
QWQIVLLDTQVFGVPHGELSEYQLEWLERKLGECPERHTLLLLHHHPLPAGCSWLDQHSL
RNAAALDDVLSRFPRVKNLLCGHIHQELDLDWNGRRILATPSTCVQFKPHCANFTLDTIA
PGWRWLELHPDGTLTTEVCRLAGAQFRPDIASEGY
>A0A8C0W7A6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Castor canadensis|TrEMBL
METFISFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSM
SRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKA
TITEPEVWYATI
>A0A1I5T7C1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterovibrio norvegicus DSM 15893|TrEMBL
MRICHLPSQHSQTVRLLQITDTHLFADPHGSLLGINTAASYKAVVEEIQAQDISFDAIIA
TGDLSQDHTAESYQRFVDGIAHWSQPCYWLPGNHDYQPEMNAVLEQSTLVRCDQVLLGEH
WQMIILDSQVKGVPHGRLTSEQLALLEQALTSYPERHTLILLHHHPLPAGSAWLDQHQLH
NQDAFWLRVEKHSNVKGVVCGHIHQALDTEHAGRRVMAAPSTCIQFLPDSDDFALDSTNP
GWREISLHQDGTISSEVGRLKGMGFHPDMNSAGY
>A0A873WDZ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Staphylococcus phage PhiSepi-HH3|TrEMBL
MKIAYLNDLHIDSWIKFNNNEHKNRKKIEEFINTIFSKSEKECLEAEILVIAGDISHHNS
ISKLTIEVFSKYFNKVYVVLGNHDYYLISKTQMRRYKANSLNRIIELNDMLADNERVVLL
HSAVNKVTDIYKGLRIAGCTMTSKPNTEEEISFYNGFMNDSRYIPNKVNDLNSMDMKSYE
DIKEFKPDLFISHYPLLMTYSHKLHLHDGSNGSFLCKVDEHIAPINFFGHVHERGDYDIG
SSFYTNAIGYKGELSNETIALKVINI
>A0A5C8YHM6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas mendocina|TrEMBL
MPSLPTQSTDSSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIERVLQEQPQIDLILAT
GDLSQDGSEASYQRFRQLTSAIDAPTRWLAGNHDEIPPMQAACQGSELLEPVIDLGAWRI
VMLDSSIPGAVPGFLADSQLELLERALSEAPQRHHLICLHHHPVSIGCKWMEPIGLRNPD
ALFAVLDRYPQARTVLWGHIHQEFDQQRGNLRLLASPSTCVQFAPGSEEFQVDSEAPGYR
WLRLHADGKLDTGVSRVTGIHFEVDYSVKGY
>A0A0P6ZNM2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIEPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAILCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTQVRRLPNGQFSPDFDAGGY
>A0A2N7JK00|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVNQGFDYEAILA
TGDISQDHSAESYQKFESGIQPLERPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEKKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTEVRRLPHGQFLPDFTAGGY
>A0A2S6X1T2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces sp. MH60|TrEMBL
MARVPAAAPHVLAEVMIRIRNAPRILTRRYRDRLARRNRPPSITPELAARSGPWTRAAGL
VAVVLLGAWLGLLVVGNVRVPVGPMDTTMTLRPSLAGGTKINVSPLGALQLDSHVAPVRL
DVNVDQLDPARAQALVDHPERLSGLQDEVAQDVEHGTLDLAVRSCVAVVTGATALGLAVY
RRPRRALGAGALALTLLVASGGTAYATWNPDSVLEPKFSGLLSSAPSLVGDARSIVTEFD
VYQKELARLVTNVTKLYDVTSTLPAYQPDPTTIRVLHVSDIHLNPASWKIIASLVRQYKV
NVIVDSGDTMDHGTAAENGFLDPVEDLGAPYVWVRGNHDSRGTQEYLKHLKNAHVLDDGH
ARTVAGLRFAGMGDPQYTPDRSEADGAEASQELAGARLASALRDQSAAGTPVDVAVAHEP
SAAREVDGDVPLVLAGHLHHEDMKVMKYGTRLRVEGSTGGSGLRAVEGKYPDPIQASILY
FDRDTRRLQAWDEIELGGLGLTTAEVSRHLPKENQPGASPSPTSAGPSATAPGGPAASAP
GAP
>A0A2N7J3M0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. 10N.261.49.E11|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLAEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHNNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPDGQFLPDFEAAGY
>A0A410X7B7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteus hauseri|TrEMBL
MESQLELSVMQKNTVRILQITDTHLFANVEDTLLGINTYRSYHAVLNAIREQGLEVDLIV
ATGDLVQDQTFEAYEHFAQGIATLTPPCVWLPGNHDYQPAMIDALNQAGILSAKQVVIGE
NWQVLLLDSQIQGVPHGELSDCQLDWLTRCLESNKQRDTIILLHHHPMASGCTWLDQHSL
RNSQALSDRLKGHSQVKMMLCGHIHQEMDEMWNGIRLLATPSTCIQFRPHCTNFTLDTVS
PGWRYLELSLSPDEKGKIETQVYRLKGTEFCPDLDADGY
>J9JTW7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acyrthosiphon pisum|TrEMBL
SLRSIKRNAHVVLVALVRKSLVLRNEKDVTSILTSGFNKIIVETCNKNVWIKELQQLEKE
DVAMRSMLAQQDAVLAALDKTKDLVIITDLKHNIQYMNKSGSVILGYAAEDVINKPLAVF
HQLGDIDQITKKLEKNIEWDGKVSWKCKSGEHVYLHCRASPFRPFGKETSNYIYIQESIV
DVHGFPRGSVPSIRKGSYDLKSINSDGAQSARRQSLAKLHNLPLEAPITKVISLICTAQE
NSNDQVVQILDKVVDILRVTELYSSHLKTENIKYDDPVTSDLIGALITQGPVHVTSTRRS
SNDSATVKSQPYGLGIAKMNFMTSVTPQIKELLDMSLYWDFNVFKLEELTMKRPLVHLGM
NLLTHFEVHKTLGCDERTLHAWLTVIEGHYHAKNTYHNSTHAADVLQATAMFLEKDRIKR
LLDQLDEACCLIAAITHDIDHPGKSSAFLCNSQNDLAILYNDISVLESHHAALTFKLTTK
DERLNIFKGLEKDTYKVVRQNIIDMILATEMTKHFEHLAKFVSVCNKPSTLDEAPVDGLT
PSEVSPEAIMPTSAEEINLVKRMLIKCADVSNPTRPLKMCVEWAKRIAEEYFNQTDEEKL
NHLPVVMPMFDRVSCSIPKSQIGFMDYIINDMFETWDSFIDMPEMLYYMRSNYQYWKDLE
EKGTISINDICKMMTTTLPKIPESSGNH
>A0A7C1WYS0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas graminis|TrEMBL
MSSASSHPSSVLVVQLTDSHLFAEADGALLGMPTRASLNAVVGLVLGEQPVIDLVLATGD
LSQDGTVESYQAFREASERLNAPSRWIPGNHDELREMAIAAQNSDFLEPVVDVGHWRITM
LDSAVSGSVPGYLQDGQLQLLAQALSEAPERHQLVCLHHHPVPIGAAWMEPIGLRNPEAL
FAVLERFPQVRAVLWGHVHQAFDQSLNGVRLLASPSTCIQFAPNSVDFGLDDLAPGYRWL
RLHDDGRIDTGVSRIAPDLFDVDINGAGY
>A0A6G8D4W6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. HDW18|TrEMBL
MKVSSQSEPSAIKLIQITDTHLFAAEDGSLLSVNTADSFSAVVAAIVEEQVEFDALVATG
DISQDHTPESYQRFVRTVAPLQTTQAQPKVCYWLPGNHDYPPSMHSVLPSEQIQAIEHVL
LGEHWQMVLLDSQVSGAPHGCLSPAQLQLLDDQLSQHPQRHSLVLLHHHPLLVGSAWLDQ
HALKQSEDLWAVVAKHRNVRALLCGHVHQEMDRMHLGARVMATPSTCVQFKPNSQNFALD
NCSPGWRELTLHADGQISSQVKRLKHGRFLPDFTSNGY
>A0A3Q0CU43|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mesocricetus auratus|TrEMBL
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSYTLGIDLWRGRRCCSGNLQLPPLSQRQS
ERARTPEGDGISRPTTLPLTTLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVL
HATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVR
NNFTLLTNLHGAPNKRSPAASQAPVSRVNLQAFPGMGFVLFAKGDTAVKLVKPFIPEMEE
TPNLCLKE
>A0A7U9NH82|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lachnospiraceae bacterium|TrEMBL
MKKVKWLHISDLHLNKVGVETRRMRNKLMEYLRENKISCEYIFITGDLRYAPAGTFDDST
VTFLNTLCSTVSVPIERLFIVPGNHDLIRDDSHRLSAIDNTCGNNGYYNYTDGMIKKEDL
DLMSSGRDEFKKIIQEIYQRIPNRIALYNNSAKPHFCIETEDFNLVHLDSTLTYTKNRQR
DLLIGTDLLMSVLEGVNQNKATIILTHYSFDFLDRREQNTVFNLLTDYNVQMWFSGHEHN
ELLRMQRDYFYEFQCGNLMHEGDGTKSCVILGEYDKETFCGVAQVYVWNSPDGWSVYPFA
SRQKDRSSYIFELQNDDAKRQQLKNIASSTICKEISDEVKIVNLYDLNEDILGSLSNEQY
KEIKNQMGLRLKGNESRLEVEKMFLNEVQMSLNSKKRYDCLPLFESVIRDTYKSFIYLDN
NLAPVTEAQVLHFYFDNEDCFQIYNDSLQLTLSTINKEVVYISFGYQLGHYKDVDERLYR
FETIRKCIESHYMHVKMIGHEEYNLSFNIPVSLESWKENIEKTHYWIDQMQRISKIEKYY
GIKFVLPERADDEELFAVEVIGDSIENKSCRTLQPLPMKHPGFKKKFSLKNEIYIGNGVE
LPMLHMFGYSFRPVAEYILSGDYNWDKKEKGWKATNSVDGIPIRVEFEICFDDDRNRKLI
QHIPYEDVQNELDEKNIVLLEGESAQFFNTYIRVTHDVQEIWQLFLSYNEQVEKFIGFDS
VDRISGKSQQQTGKIIDKITANELTNAIVYTGNTLIKHIDNFISYIDIENKPDYFSAKWT
SDNLGYAWMNVMRQYAINGHFPISVDNTGYCYYDMLAIEYEINQTDDSQLKEIIKLTRES
FQEYYPDVRKIEHYSLLRNFMYVIAIIHKTYYEFIESYLNLIAKKMNEVIFNNPELIISS
GTFEDHVVYKIDGEDIMHAFRKDSDIMMDFYKFKQHAEKHYVLNTSCMLQDT
>A0A1B7KZH1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mangrovibacter phragmitis|TrEMBL
MESLLTIPAADEASIRILQITDTHLFAGKDETLLGVNTWSSYRAVLAAIHKEARPFDLIV
ATGDLAQDQSNEAYQHFAEGVSSLAVPCVWLPGNHDFQPAMFSSLKESGISSSKQVLAGK
SWQVLLLDSQVFGVPHGELSEYQLEWLEKKLAENPDRQTLLLLHHHPLPAGCSWLDQHSL
RNAQALDDVLQRYTGVKHLLCGHIHQEMDVDWNGRRMMATPSTCVQFKPHCANFTLDTVA
PGWRWITLHPDGSLTTEVCRLSGSAFSPDTDSEGY
>A0A345H579|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kordia sp. SMS9|TrEMBL
MNQISIPPLRVRIQQVSLWQSVVAAYAVQHAKKLQKAQTPVNLTHVQEHFMVSGTSHLAA
QCEANNSIETHTFIPEPTENSTDDEFGAYFSSLFFQKAMTATDADSASKDAYKLCEELAA
RWGKKFRRYSDADDCGWAYCLEEYLKFKKQYKSVKKYNDWTKNGGLNFGVIDYKIPNDAK
VAIIGDWGTGMQDGEYLLEMILKNHQPDVIIHLGDIYYAGTPDECDANFYDIFQRLFAKY
KQIPVFTIPGNHDYYSFAYGYYQMVAKLNTGLKSKGINATQEASYFCLRTEDNGWQFLGM
DTGYCDGGPLSARFPKDGPFLHPNEPEWHQDKLDNFSGASILLSHHQVFSGNAEINGLTG
TYGSIPYLNKNLVDFFRPYFGNKVAGWFWGHEHNQVKYQNNLFGLPIGRLVGASAYEEPE
SETPYKQTFPEVPFSTDSNATLDVENEFFNHGFAIIDFSQRSHPTDAVTTQYFQYPSWGK
TAPNPIPQKTCFMWSEPFALQPQTKGKEVQFGQYIHLNLELGNAFVGPEVEHFEISREEY
LPTVRTNPVVLKISDASNSSNVVQDGDTIYLTTQEPKVGKYSHLGAWDGITTYEIYYYKY
SQADDKNMRWKIKKVIPTPNDPTIHENEAVYIFSEKFSGKYLCPYLSIINEKISTYTYLT
VSDTMNSNWFIQIQQSHSDEEVALESTSEKEGENLSFIEKMIAFIKSLFSIK
>A0A6N6RRY3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aliivibrio finisterrensis|TrEMBL
MLSETLLNNENGPVRLLQITDTHLFAPEDGALLGVPTLKSFQTVVEQVQQRTPNFDAIIA
TGDISQDHTVQSYQHFVDGIKPLVKPCYWLPGNHDYKPSMGGVLPSSQIQACEHLFIGQH
WQLIILDSQVVGVPHGALSKEQLALLDSVLSQNPDRHSLVLLHHHPLPAGSAWLDQHQLK
DNDEFWSVVGQHDNVSGIVCGHIHQELDCIVNGARLLATPSTCIQFLPDSDDFALDSQAP
GWRTLDLLPDGRIETQVHRLENCNFSADSDAGGY
>A0A6I8UUE4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila pseudoobscura pseudoobscura|TrEMBL
MGCSPSTLPNSASANANANTNAGPTAANSVPLSLDATEKDGSRLFCIKLRRSRLRRCSCG
GVALQQGDGNGNGSTAGSATCGSGTGDNLCHQVLLNPLQAKNEADYEKLSTGKKDSIVTV
AALGNFTHSVVRRATGSTGTGTSGTSSSGGGGNNRPGHRKSSLALALTPEDDPMDVYQRN
LMDLKYPTVLPPNPQLKALLVFHKSDSICEAVASACQRHQLDVTLVKSKEEALDTLQKSY
ATAQCYHLIIIDARSSKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDA
GVNRCVAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQ
YANRATERLLNMRLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMH
VRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASD
GLRRTSLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKE
IRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKANPIIMELLE
ESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIEENVCKAWLAVIEAHYHKSN
TYHNSTHAADVMQATGAFITQLTNKDMMVMDRMEEAMALIAAAAHDIDHPGRSSAFLCNS
NSALAILYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMT
RHFEHLAKFVSVFGGEEPREHNPQSDEETAILMRRMLIKVADVSNPARPMQFCIEWARRI
AEEYFMQTDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLIT
YMQINYSQWKKYDEQGVNTLADVMAMQPPMVKLANSK
>A0A447QDG7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia plymuthica|TrEMBL
MESLFKLTVASGARVRILQITDTHLFAGENETLLGINTYRSYHAVLDAIMAQQRGFDLVV
ATGDLAQDHSLAAYRHFAEGIARLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLLGE
NWQVLLLDSQVFGVPHGELSDYQLEWMERCLQDHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAVLLRYPNVNTVVCGHIHQDLDLEWQGRRLLASPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSEGY
>A0A060YL41|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oncorhynchus mykiss|TrEMBL
MFYFPHCISMYELVSLMLVIVSDLVSQFKRMLNRELTQLSETSRSGNQVSEFIANTFLEK
QHDVEIMSGPPKEKDKKKKRPMSQIVAVKKPALSPSLTPTQIPRFGVTTLQEGLLATVGG
THTHRHRHTHTHTHTHTHTHTHTHTHTHTHTHTHTHXXGGGQCK
>A0A287D089|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ictidomys tridecemlineatus|TrEMBL
GPRQALLTSCPRPQFKRMLNRELTHLSESSRSGNQVSEYISRTFLDQQTEVELPRAAPEE
SQRPMSEISGLRGLPHSASLSAATVPRFGVQTDEEGQLAKELEDTNRWGLDVFKVAELSG
NRPLTAIIFSIFQAVFTDLEVLAAIFASAIHDVDHPGVSNQFLINTSESGVPHLLSVHTQ
LIQPQGLCGKQGRWVLMLSPSLACPQVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLD
NYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKH
TASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPVDTAVSS
ERGAPDRFQFQLALEEAEEEEEEEEEALEREPSGSPDT
>A0A0P7W0P0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Scleropages formosus|TrEMBL
FDVENGPSTSCSPLNPQTPPSSGLVLHTNFPGHTQRRKSFLYQSDSDYDLSPKSMSRNSS
IISELHGDNLIVPASLRSVRKNFSVLTNIQCASNKWSPVANQPPITRVCLSEELYQKLAM
DTMEELDWCLDQLETIQMYRSVSKMASNKFKRMLNRELTHLSEMSRSGN
>A0A509BKA4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella sp. NCTC 6947|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A8C9VT52|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Scleropages formosus|TrEMBL
LASLHVTLMLPSCDLTEEAYQQLARETLEELDWCLDQLETIETHRSVSDVASTKVQISPV
LTDTRTAAPTTTM
>A0A1A7PTG5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gallibacterium genomosp. 3|TrEMBL
MSDLFQDESAGVIRLLKVTDPHLFADAESELLGINTFASFQQVLSEIKNSGFESDFILAT
GDFVQDGSEEGYHRFVKEIAQLGKKVFWIPGNHDFQPKMEAVFDVYKAIIQPHKHLLLGE
HWQVLLLDSQLYGVPHGMLSEDELAWLEHHLLMYPERNTLVVLHHHLVPTRSAWLDQHNL
RNPYDFSEVLAKHKKVKGIFYGHIHQEVNAQWQGIPVFATPSTCIQFKPDCAHFTLDSLQ
PGWREITLHPDGHIETKVQRIKEKVFLPKDNMSGY
>A0A2D4F879|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micrurus corallinus|TrEMBL
MLSSCSKLHNSPGVSSPSMTGSSPVQSKKTSMIPNLRLQRRFTVAHPLCFDVENGFSPGR
SPLSSQTNLGLGLVLQGTTPHSQRRESFLYRSDSDYDLSPKAMSRNSSISSDMHGEDLIV
TPFAQVLASLRTVRSNFAVLTHLREHVCNKRTSGPINPLSTSKVNLSEDAYQKLAIETLE
ELDWCLDQLETLQTRHSVSEMASNKFRRMLNRELTHLSETSRSGNQVSEYISNTFLGESS
ALWSSNAILEEIVKLIWKSRT
>A0A3N0YQW8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anabarilius grahami|TrEMBL
MTSPGSGLIIQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIDTVIHNSYFSNL
KAACGNVAAMHTCTHMDVQTRGIMLNRRSVSDTHVLKRTRPVREIGRFFSQPDDRWRSHG
DDLIVTPFAQVLASLRTVRNNFAALTNLQQDRTSNKRSPMCNPPPLTKASFTGYQAGFLK
AFASARGFCFPRLLSHYYWRSLVYFKTADPLTGDIKSFSETVWQVVALSDLHISDLFEEL
YGSVV
>A0A8K0V2L9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Tenebrionibacter intestinalis|TrEMBL
MESLLNLPVAGGARVRILQITDTHLFADKNGTLLGINTWESYQAVMAAIRAQQRPCDLLV
ATGDLAQDQSAMAYQHFVEGVADFPAPCVWLPGNHDFQPVMYSAFQAAGVSSARVVYAGD
AWQVVLLDSQVFGVPHGELSEYQLEWLEKTLALAPQRYTLLLLHHHPLPAGCSWLDQHSL
RNAGEFDALLRNWPQVTTLLCGHIHQEMDADWNGRRLLATPSTCIQFKPHCANFTLDTIA
PGWRWLELGADGSLTTEVCRLESAAFCPDTASEGY
>F9QAD9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus pittmaniae HK 85|TrEMBL
MLSSFVYQTDKPVVRLLQITDPHLFKDTNKDLLGINTQASFAQVLTEIQASDFDYELILA
TGDLVQDSSDEGYRLFVEMTSGLDKPLFWIPGNHDFQPKMVEFLNHHPINRLKHLLIGDN
WQILLLDSQVSGVPHGELSQYQLDWIGAKLAQNPSRFSLIVLHHHLLPTNSAWLDQHNLR
NSQDLLDVLSPFKNVKAIMYGHIHQAVDDMWFDYRVMATPSTCIQFKPDSNHFSLDTLQP
GWREIELYNDGHIETRVKRIQDAVFLPNMREDGYE
>A0A8B9QLG5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Apteryx owenii|TrEMBL
YFQNSYVNNNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMS
RNSSIASDIMQPFCLFQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITGK
RS
>A0A6I1N9B8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. MWU12-2323|TrEMBL
MPSESIQSTPADAVLLVQLSDSHLFAEADGTLLGMNTRDSLQRVIDCVLAEQPAVDLLLA
TGDLSQDGTVASYRQFRELSEAIDAPARWLPGNHDELREMAEAAHHSDLLEPVVDIGNWR
ITLLDSAVPGSVPGYLQDEQLQLLAQALSEAPQRHHLVCFHHHPISIDCAWMEPIGLRNP
EALFAVLDRFPQVRALLWGHIHQELDRERNGVRLLASPSTCVQFAPGSEDFKVDDKSPGY
RWLRLHSDGRLETAISRVRGFDFEVDYGGTGY
>Q6LUZ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium profundum (strain SS9)|TrEMBL
MQTYSLPQTNPNSVVLLQITDTHLFADESGCLLGVATKDSFNAVIDAVDASARPFEAIVA
TGDISQDHTDESYQHFSDGISRWSQPCFWLPGNHDYQPAMHSVLPSPQIKSCEQVLAGDY
WQVILLDSQVQGVPHGELSEAQLLMLDATLKAYPERHALILLHHHPLVAGSAWLDQHQLH
NNEAFWQVIDKYPKVSAVLCGHIHQELDCIYHGVRVLATPSTCIQFLPDSNDFALDKTNP
GWRYLELTREGQLNTDVCRLQGRRFIPLFNSAGY
>A0A0A2YW70|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gallibacterium anatis|TrEMBL
MSDLFRDESAGVIKLLQVTDPHLFADEDGELLGINTFDSFRQVLSEIKKSGFESNYILAT
GDFVQDNSEAGYHRFVKEIVQLGKKIFWIPGNHDFQPKMEAVFDLYKAVIQPEKHLLLGE
SWQVILLDSQLYGVPHGMLSEEELKWLEQRLSLYPDRNTLIVLHHHLLPTNSAWLDQHNL
RNPYDFSEILAKHKNIKAIVYGHIHQEVNAVWQGIPVFATPSTCIQFKPDCAYFTLDNLQ
PGWREISLYPDGRLETKVHRIKDKVFLPKDNMNGY
>A0A0A2XM69|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gallibacterium anatis|TrEMBL
MSDLFRDESTGVIKLLQITDPHLFADENGELLGINTFDSFRQVLREIKTSEFESNYILAT
GDFVQDNSEAGYHRFVKEIVQLGKKVFWIPGNHDFQPKMEAVFDLYKAVIQPEKHLLLGE
SWQVILLDSQLYGVPHGMLSEEELKWLEQRLSLYPDRNTLIVLHHHLLPTNSAWLDQHNL
RNPYDFSEILAKHKNIKAIVYGHIHQEVNAVWQGIPVFATPSTCIQFKPDCAYFTLDNLQ
PGWREISLYPDGRLETKVHRIKDKVFLPKDNMNGY
>A0A2K8W1A1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dickeya solani RNS 08.23.3.1.A|TrEMBL
MESLLTLPVARGARIRILQITDTHLFAGERGTLLGVDTYRSYQAVLDAIAAQQCDFDLIT
ATGDLAQDHTQEAYTRFADGIRRFNAPCVWLPGNHDFQPAMVDVLARSGIAPSKHVLLGE
HWQVILLDSQVFGVPHGELSEYQLEWLERNLQSQSERHTLLMLHHHPLPSGCTWLDQHSL
RNAHSLDALLVRFPRVRTVLCGHIHQEMDLDWNGRRLLATPSTCVQFKPHCTSFTIDNVA
PGWRYLELLPDGEVTTRVCRLEGNEFLPDMDSDGY
>U4JU77|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio nigripulchritudo|TrEMBL
MGYILKLSLDSSRDIKLLQITDTHLFEPEDGCLLSVNTFESFKAVVNAIRSNEIEFDAIL
ATGDISQDHTAVSYQRFEDGIALLKKPCFWLPGNHDFKPEMHSILPSTQIQTTQHVVLND
KWQIILLDSQVEGVPHGRLSEEQLALLDAKLSEYPNHKTVVLLHHHPVLVGSHWLDQHSL
KDADAFWSILSKYDKVEAVLCGHVHQDFDVIYQGVRVVATPSTCVQFKPNSDDFALDNLS
PGWRMLTLTHYGELELEVGRLPDGEFLPDFSAGGY
>A0A7X8S3C3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter freundii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPDRNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRARYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A6B0VG16|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ixodes ricinus|TrEMBL
MGCTQSGIQRRSRSHDDRSQGPATPVVCDVAPPTANATTMTAPGSLTTTAAPKGGCGAGV
LRGNAHRFENNFPKVRQKVVTCDGVNDCAVPLCSIPEDGRKGTVALKFGSMYLTVPSVRV
LFVFVKEDAQYNALKWASEKMHYEYRLACSMDEAVESYLNVQPHLVFIDARSKTCVDPIA
LCRTLRGFRGSQFSCIVAVVKKGLAEKEEAAIIPLLKSGFNRWFTETCSFGVCLNEMIQI
EHNDLINLWKLRASEALFSALHIARDGVIITGSGHEIQFMNRAAEKLVGYSVEEMLGVNA
QELHRTDSLKTDVVQTISTQLKKGKEWEGTLFHKRKSGECIPMWSKIAPVEIHTGISDHL
VYIKECPFFMEKPFSPDAVGMNRRQSFAKFHAMTIEAPITKVINMLVATQENSPVFVVQA
LDRVLEILRSTELYNPQLGVGQGKSEDQMTSDLVSGLITTGQKPTGVRRLSHETGVVKDL
QWGFPACRGTTLPTVHGDSGGVLKLAVNVTTPSTTLPSLSTAPSKIKDLLENDVKWEFDI
IELETLSGRRPLIWLGLSLFSKLNVHTSLDCDDATIRNWLQLVESHYLENPYHNSTHAGD
VMQATAYFLLKLRKKDIFDPLDEAICLISAVVHDIDHPGKSSPFLCNSDNELAILYNDRS
VLESHHAAFAFKLTLSDEKVNIFQNLEREVYRTVRLSVIDMVLATEMTKHFEHLSKFLNA
FQKPIQEDEAFESEAMPDHGDSGLRSAENIILIKRMLIKCSDVSNPARPIQLCSQWASRI
AEEYCAQTDEEKRRGLPVVMPAFDRATCSIANSQTGFINYFVRDMFRAWSDFGEFPELME
YIEKNYIYWKDKEPQSNK
>A0A514ELI2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Raoultella electrica|TrEMBL
MESLLNLPLAGETRVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRPCDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLLESGISPAKRVLLGE
HWQILLLDSQVFGVPHGELSDFQLEWLEQKLAEEPERHTLLLLHHHPLPSGCSWLDQHSL
RNAGALDRALSAFPRVKHLLCGHIHQELDLNWNGRRMMATPSTCVQFKPHCANFTLDTLS
PGWRWLELHADGTLTTEVCRLNGVKFHPDIASEGY
>A0A8J6AFD0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Galemys pyrenaicus|TrEMBL
MPVGLVANVVFKLIIILFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRS
DSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPNKRS
PMCNQPSINKATITVLRRQKDISTVLGYIELKAKCREEQEEQGVI
>A0A837LPL1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. BIDMC107|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A2T8RLH0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar 4,12:i:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A158SZG5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNEFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAEFLPNMQEEGY
>A0A7H5FSB6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNEFDVILA
TGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNVAKHLLLGEH
WQALLLDSQVYSVPHGQLSQHQLDLLKETLGKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAEFLPNMQEEGY
>A0A8D4RGW6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENKEFDVILA
TGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNVAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLGKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAEFLPNMQEEGY
>A0A8B2WPE6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLGKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELYSDGSIRTEVKRIQQAEFLPNMQEEGY
>A0A5E4MBX6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cinara cedri|TrEMBL
MGCVSSSKDVFEYHYDAIEKTNSDTLGRILHDQTANTDVWNTEIAVRNNNDLTENRLLNI
PSEMWDNCCRRSGSASDLSRDTVDAYSPINRSDSPLAQTPENNYMFGCSKYIQDLRPNPT
LKNILAVTSKEDSVWQSIATTARNLDWTVNRVTSSEEALECFHKGNGVPAVAFVDCRYQN
DKTVDAHQIARSLRSIRKNAHVVLVALVRKSFVVKNEKDVTSILTSGFNKIIVETCNKNV
WIKELQQLEKEDITMRSMLAQQDAVLAALDKTKDLVIITDLKHNIQYMNKSGSMILGYAA
EDVVNKPLAAFHQLGDIDQITKKLEKNIEWDGKVSWKCKNGEHVYLQCRASPFRSFGKET
TNYIYVQESIGEGHGYPRGSVPSIRKGSYDLKSINSDDFSFKGAQSARRQSLAKLHNLPL
EAPITKVISLICTAQENSNDQVVQILDKVVDILRVTELYSSHLKTENIKYDDPVTSDLIG
ALITQGPVHVTSTRRSSNDSATVKSQPYGLGIAKMNFMASVTPQIKELLDMALYWDFNVF
KLEELTMKRPLVHLGMNLLTHFEVHKTLGCDERTLHAWLTVVESHYHAKNTYHNSTHAAD
VLQATAMFLEKDRIKRLLDQLDEACCLIAAITHDIDHPGKSSAFLCNSQNDLAILYNDIS
VLESHHAALTFKLTTRDDRLNIFKGLEKDTYKVVRQNVIDMILATEMTKHFEHLAKFVSV
CNKPSTLDDAPIDGLTPSEVSPEILAPTSAEEINLVKRMLIKCADVSNPTRPLKMCVEWA
KRIADEYFNQTDEEKINHLPVVMPMFDRATCSIPKSQIGFMDYIINDMFETWDSFIDMPE
MLYYMRSNYQYWKDLEEKGTISYSDVCKMPLATTLPKIPESGGNNAEN
>A0A5E4M842|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cinara cedri|TrEMBL
MGCVSSSKDVFEYHYDAIEKTNSDTLGRILHDQTANTDVWNTEIAVRNNNDLTENRLLNI
PSEMWDNCCRRSGSASDLSRDTVDAYSPINRSDSPLAQTPENNYMFGCSKYIQDLRPNPT
LKNILAVTSKEDSVWQSIATTARNLDWTVNRVTSSEEALECFHKGNGVPAVAFVDCRYQN
DKTVDAHQIARSLRSIRKNAHVVLVALVRKSFVVKNEKDVTSILTSGFNKIIVETCNKNV
WIKELQQLEKEDITMRSMLAQQDAVLAALDKTKDLVIITDLKHNIQYMNKSGSMILGYAA
EDVVNKPLAAFHQLGDIDQITKKLEKNIEWDGKVSWKCKNGEHVYLQCRASPFRSFGKET
TNYIYVQESIGEGHGYPRGSVPSIRKGSYDLKSINSDGAQSARRQSLAKLHNLPLEAPIT
KVISLICTAQENSNDQVVQILDKVVDILRVTELYSSHLKTENIKYDDPVTSDLIGALITQ
GPVHVTSTRRSSNDSATVKSQPYGLGIAKMNFMASVTPQIKELLDMALYWDFNVFKLEEL
TMKRPLVHLGMNLLTHFEVHKTLGCDERTLHAWLTVVESHYHAKNTYHNSTHAADVLQAT
AMFLEKDRIKRLLDQLDEACCLIAAITHDIDHPGKSSAFLCNSQNDLAILYNDISVLESH
HAALTFKLTTRDDRLNIFKGVYTYVPIYRL
>A0A402DXR8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Helicobacter pylori|TrEMBL
MLISIAFLLVLCLLNYSSFKMLKSFLTLKKISQYAYLGFFILLSIGEAAFAFYRNTMPSH
LFVLTSACSFVSFIVFIFSLSFYGFSYSIEKIDFLHSRRKSLKNFLKLGFYLALLGYFWR
GFYEGLARPKIKETPIYLDKLDKELKIILLTDMHVGSLLQKDFVDYIVEEVNQKEVDMVL
IGGDLVDENIEKVKSFLLPLNNLKSVHGTFYVPGNHEYYHGIEPILSFLDTLNLTILGNE
CVHLGGINLCGVYDYFARKHQNFAPDIDKALKECNESKPTILLAHQPKQIRSLKESHSVD
LVLSGHTHAGQIFPFSLLVKLVQTYLYGLYKHSDTTQIYVSSGAGYWGVPLRFLAPSEIA
YLRLLPKNQA
>A0A1V0RMG4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Roseovarius mucosus|TrEMBL
MSKILIIADLHLDMWLATGRDPLAALDPEVWAGLEALIIAGDLSNKPKVRWPKLLAHISR
YITPDRIHVFPGNHDYYDHVLDGDDRLNRICTEAGARFVQKCAVVIGRTRFLCCTLWTDF
AVAGDPDLAMIRARDAMNDYRYIRMAATGHGRIRPSDTAFLHADHRAWIETQLSTPFEGQ
TVVVTHHCPHPDLIGETPCDLDGVYGSDLRAMIDRFQPDVWLFGHTHHAAEIRQGRTRIR
NVSLGYPGQVAPGDEAERLRCGIVDLERLRDEPT
>A0A740X7Y5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSLRNAGELDSVL
ANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIAPGWRTLELQA
NGVLETEVHRLQDTRFRPDTASEGY
>A0A226PQ02|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Colinus virginianus|TrEMBL
MLNVNAACSRRHSWICFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRS
DSDYDLSPKTMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTANKRSP
ATSQPPVSRVNLQELLLDEEKSRHDFPAPPAYSCYSDGA
>M4R856|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bibersteinia trehalosi USDA-ARS-USMARC-192|TrEMBL
MSDSYQWQTDADTVRLLQITDSHLFSDNHGELLGVNTNDSFQAVLNEINESSFDYDLVLA
TGDLVQDHNREAYHRFGQMVKTLEKPLFWLEGNHDTQPQMGKALSIYQQIQPHKHILAGQ
HWQIILLDSHIENLPRGELNRTQLDFLTQMLARYPERYTLIALHHNILPTHSAWLDQHSL
RNSEELAEVLFPFKQVKALIHGHIHQEVDTIWKGYRVFATPSTCIQFKPNCQHFTLDLLP
QGWRELTLLPNGQIETTIKRLKTNEFLPDFQSNGY
>A0A834QKW3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marmota monax|TrEMBL
MQGPPAPAPAPGPGSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENGLSRGR
TVLDPQSGAGLGRGAQAPAPHSQRRESFLYRSDSDYELSPKALSRNSSVASDLHGEDMIV
TPFAQVLASLKTVRSNVAALAQGQVHGAVKQASVGNPPPSSQPPPPADSGQKLALETLEE
LDWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSESSRSGNQVSEYISRTFLDQQTE
VELPRAAPEESQRPMSEISGLRGLPHSASLSAATVPRFGVQTDEEGQLAKELEDTNRWGL
DVFKVAELSGNRPLTAVIFSIFQALGFPSPDPAPRRRDTHLFQSDPPEWDNPSSRPGPGP
EGTPSGEGIWTQTPAVPWGCDAGDKDREGRDSGEDGGTCEVGRGPRRSRGCACGPDRPVM
DQERDLLKTFQIPADTLATYLLTLEGHYHADVAYHNSLHAADVAQSAHVLLATPALEVSA
AGTAGQVQGAECPPVTSPALGLSGRVHRPGSPGCHLCKCHPRRGPPRGLQPVPHQHQ
>A0A658IQ79|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Newport str. CFSAN000835|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A3G5KN27|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia pseudotuberculosis|TrEMBL
MESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTFHSYRAVLDAIIAEQHPFDLVV
ATGDLAQDHSVAAYQNFAKGISRLPVPCVWLPGNHDFQPAMVGALAEAGIAPSKQVLAGE
HWQILLLDSQVFGVPYGELSDYQLEWMERCLIAYPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAILTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDAVA
PGWRYLDLLPDGGLETEVHRLDSDEFCPDMDSDGY
>A0A4V7I7D0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bibersteinia trehalosi USDA-ARS-USMARC-188|TrEMBL
MSDSYQWQTDADTVRLLQITDSHLFSDNHGELLGVNTNDSFQAVLNEINESSFDYDLVLA
TGDLVQDHNREAYHRFGQMVKTLEKPLFWLEGNHDTQPQMGKALSIYQQIQPHKHILAGQ
HWQIILLDSHIENLPRGELNRTQLDFLTQMLARYPERYTLIALHHNILPTHSAWLDQHSL
RNSEELAEVLFPFKQVKALIHGHIHQEVDTIWKGYRVFATPSTCIQFKPNCQHFTLDLLP
QGWRELTLLPNGQIETTIKRLKTNEFLPDFQSNGY
>A0A6S7AFA2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter animicus|TrEMBL
MFHVITGLIALYVIWRFVWQLKWPAPGRVLLSVLVVLAAEHHLITRNFFGTMASPEVPAA
VLMTLGWAFGALILLAAFLFVTDVAGLVISLFSRGRGRALLGCTRLRAGSAVAALALSAV
GVWQAVRVPEVKTIEVALPNLPQAYDGFRIVHLTDLHASRLLQGDWMQAVVARTNALKPD
LTLITGDLVDGTPAARAADVQPLADLRAQYGVVAIPGNHEYYAEYLGWIEAFRKLGLRML
LNEHMTIERDGQPLVLAGITDSVAARVNQPLPDIDAAMKGVPPSSAVILLSHRPVGAKRH
AQAGAGLQLSGHTHGGQILGPHFITQLANEGYVSGMYQAGNMQLYVSNGAGLWPGFPIRL
GRPSEITQIVLRAAPPA
>E9PR34|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|TrEMBL
METLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTF
LDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLA
KELEDLNKWGLNIFNVAGYSHNRPLTCIMYAI
>A0A7Y6DG44|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas corrugata|TrEMBL
MPSVSTLTAADPVLLVQLSDSHLFAEADGSLLGMNTRDSLRAVIDLVLKQQPNIDLMLAT
GDLSQDGTLQSYEVFRQMSARIDAPARWIPGNHDEPQVMLQAAVQSMLLDPVVDIGNWRI
TLLDSAVPGSVPGFLAPEQLILLANALSEAPERHHLVCLHHHPVSIGCEWMAPIGLRNPD
ALFAVLDRFPQVRGVLWGHVHQEVDQVREGVRLLASPSTCIQFEPGSVDFAVGEQAPGYR
WLRLLPDGRVETGVERVVGFEFVVDYGAEGY
>V9GYP2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|TrEMBL
MQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVR
SNVAALARQQCLGAAKQGPVGN
>A0A2P8AZP9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micromonospora sp. MH33|TrEMBL
MVIRIAAVGDVHLDQDVVGRFRPALEELPDCADVLLLAGDLTRHGTESEARCVAQEFGDL
GVPVVTVLGNHDHQCDQVPQVVKVLEDVGITVLEGTGIVLECAGRRLGVAGVKGFGGGFA
GRCASDFGEPEMKAFVRTTNESADALGTALRGLDCDLLVALTHYSPVPDTLAGEPLEIYP
FLGCYQLGQAIDSAPTALALHGHAHHGSERGTTPGGVRVRNVAHPVIKQAYSIFHVGDHL
D
>A0A8C0QZS4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Canis lupus dingo|TrEMBL
VLILARGLGWGHLAGDQVDRGPWPGALFDLENGLSCGRSTLDPQAGPGLSRVIQASAQHS
QRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALAH
LQGRGAAKYAEGGAGAGPAGERRGRQAQAWGGACGRGQDRRGGARPGGGA
>A0A8D1TCF7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sus scrofa|TrEMBL
MKCEVLHTGPGRHWFPCVCVTCPSPVVLMGPAFCFSLSFDVENGPSPGRSPLDPQASSSS
GLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASL
RSVRNNFTVLTNLHGTSNK
>A0A3G8M0Y8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella livingstonensis|TrEMBL
MLKDAVHYSVAENEPVRLVQVTDPHLFADPEGQLLGVNTAQSLQAVLNTFIATQYPAHIL
LATGDISQDYSPESYEHFVRKIEMLNLPCHYLPGNHDDPRLMSLRMQGEKVFGQQRIIIG
NWLILMLDSTVRGKPGGYMGEQQFALIEAAIKATPDKHVLLVMHHNPILMQCAWLDQHCM
MNGENFLQRASRYPQVKGVLWGHVHQQVDNIHPGPHGPIQLMATPSTCIQFKPLSSYFAL
DHLQPGYRLLELAGDGSIRTNVYRVPGNRFAPDNEASGY
>A0A8J7KP40|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Symbiopectobacterium sp. Dall1.0|TrEMBL
MESLLKVPVASGARIRILQITDTHLFAGEHETLLGVNTYRSYHAVLSAIQAQGQDVDLIV
ATGDLAQDHSQEAYHHFTRGIAQLSAPCVWLPGNHDFQPAMVDVLAQAGIAPSKHVLMGD
AWQIILLDSQVFGVPHGELSEYQLEWLERSLLSFPERHTLLLLHHHPLASGCTWLDQHCL
RNAHHLDAVLARYPQVKNVLCGHIHQELDLDWNGRRLMATPSTCVQFKPHCTNFTIDDVG
PGWRYLDLLSDGSLETRVYRLSGSEFLPDIDSDGY
>A0A0S7GTU8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
MRRNNSRLFNVTERHWDSSEPASSVELLQDPDVRYAVKRVFSGNVQLPRLSCRPSAQERA
QDGAPPEPAAPPTRSIRHSRSLGTLTSCFDVENGLSVPRNPLDAQSSSSSGLVLQVNYPH
SQRRESFLYRSDSDFDLSPKGPSRNLSSTSDLHSEDMIVTPFAQVLASLRTVRSNFALIT
GQQDRAASKTRSSGSNPPSMCKTSLAEEPHQQLAIETLDELDWCLDQLDTLKTRNSVSEM
ASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKPDDMDIMSPTTKEKDKKKHPMSQ
ISGVKKATHSLVPSTIPRFGVNVSQEEFLAKELEDIDRWGLDIFKVAEYSGKRPLTVTMY
TIFQERDLLKTFKIPADHFINFTMTLEDHYRSDVAYHNNIHAADVVQSTHVLLSTPALEA
VFTDLENHHLAVGFKLLQEDNCDILQNLSKKQRQSLRKMVIDMVTPTSQPAQFREFRLSG
VF
>A0A0S7HF90|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
SAAMDPLGPDYVSVCLLADESYQKLAMETMEELDWCLDQLETIQTHRSVSDMASNKFKRM
LNRELNHLSEMSRSGNQVSEYISNTFLGKHCSITERLQQSSERCEAASVRTNRVSDS
>A0A3S5YMP3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. arizonae serovar 18:z4,z23:- str. CVM N26626|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYGALQEAGISPAKHVLIGE
EWQILLLDSQVFGVPHGELSEFQLEWLERKLANAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSLLAHFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A7T8NMJ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas media|TrEMBL
METELPQAPDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQANAHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGDHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHQGVRLIASPSTCIQFKPLSDGLSLDESGPGW
RYLTLHPDGRIASQVWRLPVGQFVPDPDATGY
>A0A5N3SCQ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio fortis|TrEMBL
MELSHTSKLDESSIKLVQLTDTHLFAPSNGSLLSINTEDSFRAVVDGIVNQGYEYEAVLA
TGDISQDHSAESYQKFEAGIQPLEKPCYWLPGNHDYKPNMGSVIPSAQIQCVEHVLLGEH
WQMILLDSQVVGVPHGRLSDQQLELLEQKLAEHPQKHTLVLLHHHPLLVGSAWLDQHCLK
DADQFWDVVSQHNNVRGVLCGHVHQDMNREHLGVQVMATPSTCVQFKPNSDDFALDTLSP
GWRELELKPNGEIATEVRRLERGAFAPDFNAEGY
>A0A4R5K3D3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. H9|TrEMBL
MPQSSIPLSAAPVHVVQLTDSHLFADAHGTLLGMNTRDSLQRVIEKVREEQPRIDLLLAT
GDLSQDGTEASYASFRDLTAALGAPARWLAGNHDEPVPMERVAQGSDLLEPLLDIGNWRI
LTLNSAVPGAVPGVLDDGQLALLEQSLRDAPERHHLICFHHQPVPIDCAWMAPIGLRNAE
ALFALLKGYPQVRALLWGHIHQEWDQWHGDVRLLASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLHVDGSIETGVSRVTDFAFTIDYAGDGY
>A0A3L0W322|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQVNEHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VMLLDTQVRGKPHGVLGDHQLAALDSALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEVDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRVASQVWRLPVGQFVPDPDATGY
>A0A385EYY4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter baumannii WM99c|TrEMBL
MWNPNSIIFCFYLIFSILALWGIIEAWVHQSRTETIHPFKAFVHLLAFYLSYLLIPLWFF
NLYAGWIGYYSIHETIFIFLLSGILIYARFIEPHMVRVDVHQYRLNPDRRFAKPVKVALI
ADLHIGLFSGHERQLKIIVKKLNEQQPDLVVVAGDWTYEPEDKLVQELSVLKDIKAPVYS
VPGNHDEQYPGPPIQQLLKDALHYNDVMDIEGKIVEFDEFRLIGIGDLWAGKTDMRSMPD
LPQDKPWLILSHNPDTVDMVPKLPNRPLMLSGHTHGGQVELPWVTNYIMKKVSILGHKRG
FYSHEHADVFVTVGTGMVGIPLRFRVPPTIDIIELV
>A0A5E4VW48|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea cepalis|TrEMBL
MNQEQTRRIKVAHLSDLHFSIGNLLEAGQCFGSAVSTAISERVDVAIISGDLTDHKQDAH
SAALHQLMQELRRLADHCPVLILQGTFLHDYPGMLAIYRFAGGKYPVETVDKIGQVALVG
TQWRYVSPGDSLDDARLLVSCVPTVNKSDLVSSVGAEHVAQAMGDVLAGLMQGVFAPQNI
AASAAGVATVTVGHGTVSGALTEHGVPMAGKDHEFSLGGLYAAQSTATMLGHIHRHQSWD
REVGGFVQRVAYPGSIGRFHYGEEGKKGFLIWNIGPRDCDFEFRETPARVMVDFLFDGVP
DMAWLEEQAASCVGSFVRVRYSVDAELAVTVDKQAIEQVLAQAAEVRIEPKLLASQRQRC
SGISTLSTLAEKVEKWCKSTDNDASVVVPRVRLLGTSDARSIATSLIKELFHEAESRTHE
HRDDAGHAVDPFARAERGLDHSAGRELAQ
>A0A837FXI3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. SM3|TrEMBL
MDSLLTLPAANGADIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIMAQQRDYDLII
ATGDLAQDHTVEAYQHFVAGISRLPKPCVWLPGNHDFQPAMVNTLADAGIASDKHVLLGE
HWQLVLLDSQVFGVPHGMLSEYQLEWLDKALRQHPERHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLQHFPRARNLVCGHIHQELDLDWHGRRVLASPSTCVQFKPHCTNFAIDDVA
PGWRWLTLKADGVLETEVNRLQSDLFRPDLDSEGY
>A0A6J5B4P1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia sediminicola|TrEMBL
MKIRVLSDLHLENDEPELIPHAEADLIVLAGDIHNHAAGPRWAAQTFDGAVPVVYVPGNH
EYYDGEFGALDTALYDAAAQVDNVHVLNNAALVDPQGRWRVLGTTLWTDFALYGADPDTL
AESIDASRRAMLDFRGLIQMNWPHDTQDSPRDFTPDDSLALHRRARAWLESELAKPFDGK
TIVVTHHAPHRLSLAERYAEDRVSAGFVNHLPNLVRSPIALWIHGHTHTPFDYTVNGTRV
VCNPRGYFDRRTRQWENPQFAWDKVVEI
>A0A5B8REL5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured organism|TrEMBL
MSDNTSEPPGGVKPLRVLQVSDTHLYADPAADLAGVPTSGSARAVLDAALAGEAPDLIVA
TGDLVHDGSAAGYERLRGWLADSGVPALVIPGNHDDPVAMARCFAEAPVTWRESVSIGGW
QVIALDSHVPGEPWGRLGTAQLERLDGHLAAADTPVLVAVHHPPVAVGARWLDGIALADG
EALLARLGACGRPAVVIWGHIHQAFEGWYGGVRLLGAPSTCIQFAPLSGEFALDIRPPGW
RELTLHPGGGNETCVGRLSDGAFRPVTDCEGY
>A0A5P1DCP2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas haemolytica|TrEMBL
MPSVSNVKPDASALLVHLSDSHLFAEADTTLLGMNTRESLQRVIELVREQQPQVDLVLAT
GDLSQDGTLESYQQFRDMTRRIGAPARWIPGNHDEPQVMARAAVNSDLLEPVVDIGNWRI
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPSRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRALLWGHVHQEIDSERNGVRLLASPSTCIQFAPDSEDFQVSEQAPGYR
WLRLHADGRLETGVERVEGFAFTVDYGSNGY
>A0A6L6HAF7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia sp. CPCC 100877|TrEMBL
MESQLNLPVAGGASIRILQITDTHLFADKSGTLLGVNTWASYQAVVEAIQARQDHWDLIV
ATGDLAQDQSAQAYQYFADGIAGFSAPCVWLPGNHDFQPAMYSALQEAGISPAKVVYAGD
AWQILLLDSQVFGVPLGELSDYQLEWLERQLSRAPERHTLLLLHHHPMPAGCSWLDQHSL
RNSPALDDVLTHWPRVKTLLCGHIHQELDIDWNGRRLLATPSTCVQFKPHCANFTLDTIP
PGWRWLELAPDGTLTTGVCRLETQDFSPDTESEGY
>A0A329IZ34|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. RIT 412|TrEMBL
MSSASSNPSSVLVVQLSDSHLFAEADSTLLGMPTRDSLHAVIGLVLEEQPHIDLVLATGD
LSQDGTVASYQAFLEASDRLDAPKRWLPGNHDEVREMAIAARQSDVLEAITDIGGWRVTM
LDSSVSGSVPGYLEDKQLQILVQALSEAPDRHHLVCLHHHPVPIGAAWMEPIGLRNPEAL
FSVLDRFPQTRAVLWGHVHQVFDQPRAGLRLMASPSTCIQFAPGSDDFALDSQAPGYRWL
RLHDDGRIETGVSRIDPDLFEIDLNGAGY
>A0A3Q2XSU5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hippocampus comes|TrEMBL
MARPLPHYAQSPSAESLLTVCLYKLAMETTEELDWCLDQLETIQTYRSVSDMASTKVQQA
LIL
>A0A653PJW0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Halomonas titanicae|TrEMBL
MRVVQITDAHLYADTEARSRAGIPWRQFQQVLNAVVAEKPEIVLFTGDISQDESAASYAL
AVQALEQLPCPWYWLPGNHDQPEFMAAERPMVEQVDLDSWRILLLNTQVEGKPHGELGSE
RLAKLAEQLENDDRPTLIAMHHPPVDVGAVWMDAIGLQDRDAFWQLLSKHPHVKIILFGH
AHQAYVEHHILGTGRGIGEATIDVYGCPAMADQFLPGAEQFAIDEASRPGYRVIDLAYSD
VQGSEWQSWIERID
>A0A7J6B320|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ameiurus melas|TrEMBL
MRKSRSVLTVTPEDENKDLPACTGATLRSELRCCYRRHSGTPTLPPLSWRHTERTRSPEQ
DLVSRPTSLPFSDPPRIDITPVPPESLEAENGPCSPVELQVSPGSALLLPHGQRRESFLY
RSDSDYELSPKSTSRNSSIMGELHGEDFIVTPFAQVLASLRTVRSNFSILTNVPGPSSKR
SPVTMQPPLNRASLSDESFQKLALETMGELDWCLDQLETIQTHRSVSDMASNKARGGRFP
VDDLVPVFTLIRNQKNQDAEPGMGRDHTNTYSNEILRF
>A0A6N8AR52|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alcanivorax sp|TrEMBL
MITTGAGILTHPVQPLRVVQLSDFHLFADTDGKLLGLNTQFSLEAVLDRVRREQPDMDLI
LATGDLSQDGSYESYQRLAKTLSGFRAPIYWLEGNHDKPAPMLRALRGQDNRVSPCVADI
GNWTLVLLDSTIPGEVPGDLFDEDLKFLDDALRDAAGEHLLVCLHHHPVPMGSEWLDTQL
VGSAERFFEVIDAHPRVRGILWGHVHQEYDDTRNGVRLLAVPSTCVQFKPGSADFAVDDT
SPGYRWLDLHADGGIDTAVSRVEGIHFEVDMSVKGY
>A0A6S7CW37|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter dolens|TrEMBL
MARVHTLARRTDAPAMLVQLTDCHLFGEPDTVMLGVNTDASLRAVLRQIEADGKHPDLLL
ATGDLSQDGEPAAYQRLAAILGAAPALEGARIRCLPGNHDLPVAMRHELPEWSVPVTDVG
AWRVVSLDTTVPGSNAGHLPDSQLDLLEAALAEAPGRHTLLAMHHNPMQIDSHWHDSMMI
DNPQALFKLLARWPQVRVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNLA
PGYRWIKLYQDGSMATGVRRVQDALWHATQPGPASAQAA
>A0A7U6J8E4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas hydrophila|TrEMBL
MILETELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHPFDLIL
ATGDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEH
WQVILLDTQVRGKPHGVLGDHQLAALDQVLRQHPERHALIALHHQAVPVGCAWLDQHNLK
NADDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGP
GWRYLTLYPDGRIASQVWRLPVGQFVPDPNATGY
>Q87SJ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)|TrEMBL
MQSSNDSIKLLQITDTHLFAADEGSLLSVKTADSFSAVVNEVLRRKVGFDYILATGDISQ
DHSAESYQRFADSIAPLQKDCYWLPGNHDYKPNMGSVLPSPQIQAAEHVLLGEKWQLILL
DSQVVGVPHGRLSDQQLTLLEEKLTEFPERHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFDNVKGILCGHVHQDMNVIHKGIRVMATPSTCVQFKPNSDDFALDTTSPGWRELE
LHTNGDITTHVDRLPEGQFQPDFSSNGY
>A0A2D0IKT3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus ehlersii|TrEMBL
MKKINQSTLPYLMFIILLFLSTFSIRALSSTLISIKNSTDSILELDSSSLKNGTWSTKPP
QKVLMGERVNFMFDNSRMNNTEGTAVYKASDGAKITIHWNIPFFGKNSYDITTNKQDSYL
TGYSLIHGENTGIRVTFLKKHLTRNYKVIVMSDPQPWRLETGDPNAFANEEPWKNRNRNV
VKSINELHLQGLVDFGIINGDMTEFGRQNTRDDFYLIYNKLLFPFYFGLGNHDYQNNVND
CTEYWHFDFSKNACARWSVDNMASEISDNYQNEQLLNFNSDYNNDKHSGSLAYSWDFGNI
HYVQLQNYPTYWVTLDHYAAPTIYIKNSMAWLKTDLTKAYSRGKASILNFHDGTQSFIQK
STDEQKKEFKNLIEKYNVMAVFIGHTHQVKESNKNGGDPIFGNARIYNSGALFQGDFLLM
NVRNKCIDVSVYNGRDGTPRKIQDFQGTCGKLTHQLNQ
>A0A5D3GD35|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas synxantha|TrEMBL
MPRVPTMNPDAALLVQLSDSHLFAEAGGTLLGMNTRASLQSVIDLVHEQQPRIDLVLATG
DLSQDGTLASYQLFRNMTAPIGAPARWIPGNHDEPQVMAEAAVQSDLLEPVVDVGNWRIT
LLDSAVPGSVPGYLQDSQLQLLAQALSEAPSRHHLVCLHHHPVSIGCAWMEPIGLRNPEA
LFAVLDRFPQVKALLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFQVSEQAPGYRW
LRLYADGRLETGVERLRDFAFTVDYGSNGY
>A0A6P8LNT3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bombus bifarius|TrEMBL
MGCKTSMLECIEDTGEAEKRKHSDMVNQGSLLGKTEYDVLRRRSSFEDVAVDDDENADCS
ALKGPQNIEAHPLTNSVPSLIKILLVFPKDDQQMDVLATTSRRLGWSVSVAKDAEKAVEF
FQNRGHELVIIDHRGQRAAEADTICRYGELFFKNQPNSSGVRLYILINTIYFRAIRSSPA
YHNSIIIALVKKSFLMHGEKDKIVTLDLLETGFSRALMECSHERLLINELVGIYASALLP
RTQLAAANALYVALDRCRDMVHVTNDKHIVQFVNKISEKLLGYKTSEILGKSIADIVVYD
NFVLMEQHISKGREFEGNMNCKRKNNQMITISCRVIPFSISLKKPTHYIYIYDTTYLSEN
IGSLSPTPSQSVYSRGNMIVSQRRTSDMKSSEGRRRSSAHKLHSLQLDAPITKVISLLSN
AITESTTPDTAAQIEKAIDILKTTELYVPSLREDTDPVTTDLVGALLASPRKAWESRRSS
VESTRVSMSKAFTTTTSSRMQIKSFRGPQEIAEILERCLEWNFDIFKLEILTEKRPLLFL
GTTIMNMYRVPARLGCEEKVVQNWLTVIEMNYQSRNSYHNSTHAADVLQATARFMQSERL
QQILEPLDEVATLVAAAAHDVDHPGRSSQFLCNSDNKLAILYNDLSVLESHHAALTFKLS
LSDDNVNIFKNLERDTYKQLRQTVIDMILATEMTKHFEHLAKFMNICSARMMDSPQLDDY
TDTVDMSVVLQPENVVLVKRMMIKCADVSNPTRPLKCCVEWARRIAEEYFNQTDEEKRMQ
LPVLMPMFDRATCSIPKAQIGFVDFIINDMVEAWDAFIDMPEMVGYMRQNYEKWKEYNPK
KMKDTVIESYF
>A0A1D3L2P5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methanobacterium congolense|TrEMBL
MAFIAHISDLHVGSLNFKEDLLIQAINNVNDMHPDVTVVTGDLTENGYYLEFEKAARYLD
MIKSPMLVVPGNHDARHVGDECFEELIRERYGTLKLKKHGVKIIGLDSSEPDLDYGKVGR
SQQTWMENELQSSEDDGLYKIIALHHHIIPVPRTGRERNVLSDAGDILQSVVNGNANLVL
SGHKHMPHVWILENTAFATAGTVSSLRLRGKELSSFNTIIIEDDFIEIILNRADGTRRCL
AKYENTCKVIN
>A0A7Y3R543|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. 12-2(3-a)|TrEMBL
MNVSPSLSPSDHIKLVQITDTHLFAPDDGCLLSVNTADSFRAIVQAIIEQQIHFDAILAT
GDISQDHSAESYQRFAAGIRDLQKSCFWLPGNHDYKPNMGSVMPSAQIQALEHVLLGKHW
QMVLLDSQVVGVPHGRLSDYQLGLLDEKLTQYPDRFTLVLLHHHPLLVGSAWLDQHTLKD
SDAFWHVVGQHRNVRAVLCGHVHQAMDCEYQGVKVMATPSTCVQFKPNSDDFALDLCSPG
WRELELHHDGEVSTQVKRLRKGAFVPDFTSSGY
>A0A8E1YY11|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter haemolyticus|TrEMBL
MTYQVSTSSQQDFVMIQITDTHLLEYPHLEFVGMQPEQSFHAVIDLMRQQHPQIDLIVHT
GDLAQTPTPVTYNRYIQHMQSLEIPFFHTPGNHDDVAHFPFHEVDQTQLTVIELGKWVII
LLNSAQPQRIDGRITESQLKQLHTLLSRLHDRYVILACHHHPFAMQSAWIDQHKLKNASD
LLETVKPFSNIKAIVCGHVHQDAIHQWQGIEFLSTPSTCIQFKPKSEKFALDEEHPGYRY
ICLKANGELETQVYRLKTSERMSSSEVLGYD
>A0A0T9NEI5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia kristensenii|TrEMBL
MESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAEGISRLPAPCVWLPGNHDFQPAMVDALANADIAPSKQVLVGD
DWQILLLDSQVFGVPYGELSDYQLEWMERCLIAYPERYTLILLHHHPIPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGKLETEVRRLASDEFCPDMDSDGY
>A0A5H7Y4I9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Wentworth|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A6L9DS70|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter haemolyticus|TrEMBL
MTYQVSTSSQQDFVMIQITDTHLLEYPYLEFVGMQPEQSFHAVIDLMRQQHPQIDLIVHT
GDLAQTPTPVTYNRYIQHMQSLEIPFFHTPGNHDDVAHFPFHEVDQTQLTVIELGKWVII
LLNSAQPQRIDGKITESQLKQLHTLLLKLHDRYVILACHHHPFAMQSAWIDQHKLKNASD
LLETVKPFSNIKAIVCGHVHQDAIHQWQGIEFLSTPSTCIQFKPKSEKFALDEEHPGYRY
ICLKANGELETQVYRLKTSERMSSSEVLGYD
>A0A418RGD5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylococcales bacterium|TrEMBL
MTDLSILQITDCHILPCINDNFLGINTEYYFRAVLELALEENRHFDLIIVSGDLAQDPSH
ESYQRILKYLEATKIPCVCLPGNHDDLQLMQQAFNTPLVNCQKQFLLGKWQCILLNSQIE
GESGGRLSNQELNFLDECLSRHPDYHALIAVHHHCLETKSAWMDTMIIENNLELWTLIKK
HPQVKAVINGHIHQVMDVEHFGVRVLGSPSTCFQFKPNSPTFSLDDKVSPGYRQITLCSD
GNIQTFISRLSEPLKGLQIDSLGY
>E6KWE7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aggregatibacter segnis ATCC 33393|TrEMBL
MLNTYQYNTQQDVFRIVQITDPHLFKDTNGELLGINTQASFSQVLSEIQQQQYDYDLVLA
TGDLVQDNSDEGYLRFRQDVKALNNKMVFWIPGNHDFQPKMFEILKEETVSAKKHILLGD
KWQILLLDSQVQGVPHGQLEAEELDWLKLKLQEYPERYSLVVLHHHLLSTGSAWLDQHNL
RNANELAEVLAPFKHVKALLYGHIHQQVDSEWLGYQVMATPSTCIQFKADSNTFALDVAQ
PGWREIDLHADGHIETRVKRIQQASFLPNMQVEGY
>A0A7J0APU5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MVLDNIDCSKYVGGGDSNRKNQVAGKIYSPQFSWLAKDLSYVDKSTPVIITMHVPVYSDS
KPGEFSARTYSPEVLAAVEGYNVHFVTGHTHRNYNALPGNKGVDNVYEHNVGAICSDWWW
SGAVTPGCLMAPDGTPAGYAVWDITGKDFKYTYKCAGKDENFQFRSYDLNEVSFSSSDVE
GLNSTMAAIFAAKIADYTGQKKNEVLLNVWNYNTRWTITVTTADGKALDVRHVSAYDPLH
IAANVLKRWKGSPTSEPIGSTTKDHHFFKVTAPDADTDLIITVKDEFGRTYTENMQRPKA
FGTDAYKIEIK
>A0A7J0BD20|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MNHLPTIIQRTLIFLNIFVFLILSSAKGHCINHTAPENESGAIMIDTPNITGTVADINGN
PIAGAIVSDGKNIVLTDSTGFYSMNSDKTKGTVWVSIPRGYEPPISGSRPQFFASLTRPK
KVAERHDFVLTPIENPDSYALLVHTDQHLTGRPTGDIEQFRSFIIPDFNSTIAQYRAQGK
HVYSISLGDAGWEKHWVEYSFGLPDVACEFDRIECPVFSVIGNHDYNPYVSGDTNSTDIF
RKNFGPTYYSFNLGRIHYIVLDDIVYINANATPTEMGDRDYRRRLDADQLRWLKADLATL
PTTSEPIVICSHIPFYSAPALNDNGSLTVTNSLRNVEEIEEILRPYNNIKVFTGHHHRAY
NVESPRHKGITEWVYPAICATMWRTKQLAGNHITADGCIGGYGIWTVDSTDMSYRYKSPG
YPADYQMRVYDLNTVLINAKLVSNKAAKSKVAKCAHGYNKRNKRNELLINVFAYGPGWKV
EARENGLPLKVEQVAASDPLHILSYEIAQLNNGEHNAHSKSNPSIHFFKATASAPDTQVT
VTVTDPWGHIYTETVERPKAFHKLMK
>A0A7J0B9E6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MKLEKPTKYKNTHTLAVLLTLSTFLAAVFISGCASSPHALQENKGQTETAQQPNADTGQN
KTENADTRHQESIEITPEAIDTCQITIPGISREYDLLFFTDTHIIIPETSKEISQEIRDY
SSQRLSEFAGESQFASSDLFQALLSYANDTKPDAVLLGGDIIDSPSPSNMDFLGNSLEKL
EIPYIYTLGNHDWTYPWEYMTETAVNDYLPPLSPYMDGNTSIHTLELDDFIIAAVDNSSN
QINPDALETYKTILTLDKPVLLLVHVPFYTPSLLEEASGFWQQSVVLGGGVHGGTYPNEI
SAEFMGLTTAASSPVAAVIAGHVHFPHVSDMEGEKGIPQIVGDAGFKGRATRIHISP
>O77822|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oryctolagus cuniculus|TrEMBL
PWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTSKEREQTP
RQKPSPQPPAPVPPFQPMAQITGVKRPTHSLGDSGIPRFGVKTDQEELLAQEL
>A0A5F9CD52|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oryctolagus cuniculus|TrEMBL
SFPRSRCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKS
MSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQERAPSKRSPMCNQPSINK
ATITGKKDLGAYSLRV
>A0A182WX29|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles quadriannulatus|TrEMBL
MESLCKPAPAVLTVKQLESMPQAERTRPARRYSLVGTPSPTVYVDERKTTERISSTTVPA
DVYLRTNSTPIFRPRSYGRRSNGLKVFRFPDIMEESVFAEQTTTLSAREWRRFVAFRSLP
ADSIDPAFRQQILADYDVHFYEYGELAASSAQEVVSADTVTFAVGEPTAGSSHVQDTILP
TLSEEEAIFIERLVSDLKFPNLLPPNPVIKILIAFCKNDPVFEALVNASHRLSLEPTFVK
SAESAIDAFQNPSSGGHHIIIVDARYPRTIEAEALGRSIRNSKGSQHTTMVAVVKKSVFE
KDDTAVISLLDVGYNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQALYTALHRSRE
AVIITDDTLRAQYANRASERVLNMKLDEIVGRSLSDLVTADISNILSHTSRYKDYDGYLT
TRRKSQESSQIHVRAVPVSCIGRNPTHLVLILESSSSALVSTNAIGEALQTLPQGKEVPR
GSLHSIRRGSFDVRSIASDGLRRTSLAKLSSLPLEAPITKVLSLLAQVQENCSLDEAKLL
DRVMEFLKREGLYSPQMKEIRTEDPVATDLIGALLTQGPTNILSSRRSSNDSIIRGGGRP
STGSIVFNKTKESSQLSDLLQTALDWDFEIFKLEDLTEKRPLVCLGLELFRRFDVYNTFN
CDEMTFKLWLIEMEKHYHSENTYHNSTHAADVMQATAVYLQQLSNRELKIMDRMDEATAL
IAAATHDIDHPGRSSAFLCNSDNTLALLYNDICVLESHHAATTFRLTLGDDKINIFKHLD
RDMYKLARSIIVDMILATEMTRHFEHLAKFVSVFGTDVESKDPLPPDNDDNQILVRRMLI
KCADVSNPTRPLKFCVEWARRIAEEYFMQTDEEKRKNLPIVMPMFDRTTCSISKSQIGFI
EYIIHDMMDAWNSFIEMPEIIRYMEFNYSQWKLFEEQGINTLSDIKRKQMSLTEDTASSI
SLEEKF
>L5L347|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pteropus alecto|TrEMBL
MTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQ
VLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEKWMLCLYNTKHLEEKNSQ
PKLVNKRFISKVCF
>A0A7V0PN90|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chromatiales bacterium|TrEMBL
MFARQKAGRFPSPAHGDPVPLHWGAVRDRAGWPSGPPAGSLRVLQVTDTHLYRDADRTLL
GINTQRSLEQVLEQARYEHGPADLVLATGDLVHDHAREGYARLRALLHSLGAPGYWLPGN
HDDPQVMREVLAGAGACDPRSVRVGRWQIVLLDSRIAGGGDAGRVSHAGLRSLDEDLGRY
PDHHALVCLHHPPVPIGSRWMDAIGLQNAAELFAVLDRHPQVRAVLCGHIHQEFETRRAG
VRILGSPSTCFQFRRRSDEFALDSAAPGYRWLALHADGGIDTGVGYLEDFTAAVDMASTG
Y
>A0A7G9Z4P2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methanosarcinales archaeon ANME-1 ERB7|TrEMBL
MKIVHISDIHVAEQHFLPDLLERVIIDINEIEPEIVVVTGDLTENGYQSEFKRAKSYIDK
IECNVKVVIPGNHDARNVGYLGFEEIFGHRSLKEKYKGITIAGIDSTQPDLDDGHVGREK
YGWIEKCMDTGDFKVVALHHHLIPIPKTGREKQIPMDAGDVLELLVRCKVDLVLCGHRHV
PWIWNLNGIIITNAGTACTNRVKWNIPQSFNLIEIEEEEKGTIKIYRMHSKGGQELVLEK
RIDKATK
>A0A6G6HPM6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Glaesserella parasuis|TrEMBL
MDDSYIFPLSSPIIRILQITDSHLFASDTCELLGVNTTQSFQAVLNMIMKESFEYDLILA
TGDLVQDHNREAYHRFAKMVKPLVKPLFWVAGNHDLQPQMRNALSIYSQIKPEKHILVGD
HWQIILLDSHIQDSPKGRLEFSELAFLKRKLEVHPERYSLIVLHHNILPTNSAWLDQHSL
SNVNDLLATLKAFPKVKAIVHGHIHQEVDAQWNGYRILSTPSTCIQFKPHCNDFTLDAIP
QGWRELCLNIDGFIDTVVKRLDNNNFLPNFKALGY
>A0A6J0BJ25|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Neodiprion lecontei|TrEMBL
MKNANTLAMNRAPRSSTRSVQSFQSFADVDREELDGNAGMPDTRRQTKPILYVYGPTESE
NPNTSIEDSDTWFTRLIPGICTRLAATCCQSRYVMEVKEPAIPIVIPVTYKGPQDLKSNL
LTSWSPSSTKIMLVFGRDDHQSEVLGSAAKKLGWSVTYSRSTDTALETFHSRGHDIVVID
HRGSRGIDSDSLCRLIRASGVNPNTVIVALVRKSFLINADQDQIMTIGLMGIGFNRTLLE
CSQENLLANELVNIHASELQPRLHLAAFHALYVAVDRCRDMVHVTNDRHVVQFANKASER
FLGYKPEELLGNKIMDIVSSDNFVLMDQHLRRGREWEGNMNCKRKSSKTITVNCRIVPFS
ASGRTPTHYIYVHDTTYLLENMAIGPGNTGTQQMPRGSVHSLRRGSFDVKSTGSETHRRS
SFTKIHNLPLEAPITRVIGILSTALNDMSTTSPELALQMYKAIELLKGTELYTPQLREDT
RGYDPVTEDLVGALLASPVYARDSRRSSNDSVSRIPTSKTLTNASAHRMSLKGYRPPQEI
HDMMEKSLDWDFDIFKLEVLSCGRPLVYLGMNLIGLYEGPATLGCDEKTFFNWLTLVEMH
YHADNSYHNSSHAADVLQATAKFMRSERLKMIFDPLDEVTALIAAAAHDIDHPGRSSQFL
CNANNKLAILYNDLAVLESHHAALTFKLTLADDRANIFKGLDRESYKVARQNVIDMILAT
EMTRHFEHLAKFVNVCSNRMAACFRGY
>A0A8A2WFJ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Glaesserella parasuis|TrEMBL
MDDSYIFPLSSPIIRILQITDSHLFASDTCELLGVNTTQSFQAVLNMIMKESFEYDLILA
TGDLVQDHNREAYHRFAKMVKPLVKPLFWVAGNHDLQPQMRNALSIYSQIKPEKHILVGD
HWQIILLDSHIQDSPKGRLEFSELAFLKRKLEVHPERYSLIVLHHNILPTNSAWLDQHSL
SNVNDLLATLKAFPKVKAIVHGHIHQEVDAQWNGYRILSTPSTCIQFKPHCNDFTLDVIP
QGWRELCLNIDGFIDTVVKRLDNNNFLPNFKALGY
>A0A6I5WN23|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Glaesserella parasuis|TrEMBL
MDDSYIFPLSSPIIRILQITDSHLFASDTCELLGVNTTQSFQAVLNMIMKESFEYDLILA
TGDLVQDHNREAYHRFAKMVKPLVKPLFWVAGNHDLQPQMRNALSIYSQIKPEKHILVGD
HWQIILLDSHIQDSPKGRLESSELAFLKRKLEVHPERYSLIVLHHNILPTNSAWLDQHSL
SNVNDLLATLKAFPKVKAIVHGHIHQEVDAQWNGYRILSTPSTCIQFKPHCNDFTLDAIP
QGWRELCLNIDGSIDTVVKRLDNNNFLPNFKALGY
>A0A6C8EZG8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Virchow str. SL491|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>Q3TAQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus musculus|TrEMBL
MKEQGGTVSGAASSRGGGDSAMASLQPLQPNYLSVCLFPEESYQKLAMETLEELDWCLDQ
LETIQTYRSVSEMASNKVRTPLSLTTTGAPGSSLSVDLVEVRQHFLCSYLATTVS
>Q8BTA5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus musculus|TrEMBL
MASLQPLQPNYLSVCLFPEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKVRTP
LSLTTTGAPGSSLSVDLVEVRQHFLCSYLATTVS
>A0A7T4VVF1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens BBc6R8|TrEMBL
MPSVSALNPDASALLVQLSDSHLFAEADGGLLGMNTRESLQRVIDTVLVQQPQIDLVLAT
GDLSQDGTLESYQAFRDMTRQIQAPARWIPGNHDEPQVMQQAAVNSALLEPVVDVGNWRI
TLLDSAVPGSVPGYLQDQQLQLLAQSLSEAPARHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFSVSEQAPGYR
WLRLHADGRLETGVERVEGFAFQVDYGSDGY
>A0A6L5HT77|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas helleri|TrEMBL
MPNASTPTTEHSVLLVQLTDSHLFADADGSLLGLNTAQSLQQVVDKARAEQGQVDLLLGT
GDLAQDGSVAAYQRFRQVSEPLCANARWLPGNHDRLAQMREATVQTRLLDSVVDIGNWRI
ILLNSQVPGATPGYLEEEQLQLLARAVSEAPQRHHLVCLHHHPVPVGSEWIEPIGLRNAK
EFWAVLDRFPQVRAVLWGHIHQPFDQIRNNVRLLATPSTCVQFTPGSTDFDVSGEAPGYR
WLRLHSDGALDTGVSRLDNFVFTPDYSANNY
>A0A6M1ZNM8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chlamydiae bacterium|TrEMBL
MKPIRLVHLSDPHFASVTYSPRQFFSKRWLGNCNLILFRKKAYQTAHLKHIPELLETLDV
ETVFLTGDVATTSRDEEFAKAAAFVSEFKQPVHLVPGNHDCYTRGSDRGKRFYRYFPEPE
LQEHRVVKKKLGKGWWWIGLDCALATALIFSYGRFSKEMEKKLEDALSQIPTDEGVVISN
HFPLFGSGSPRHDLRRNAALQKILRRFPQVKLYLHGHDHSPYIIDKIREGYPLVINSGSC
AHQPNGIFYLMDLDRTGCLVERCVLKQENSTYSWVVESQKRYHFL
>A0A1V3GUY6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salinivibrio sp. ML290|TrEMBL
MQSCQIDNADGDCIRLLQITDTHLFASEQGSLLGINTLRSYHAVLDAISATDPTFDAIIA
TGDLSQDHSALSYRRFVDGIARWSQPCFWLPGNHDYQPEMSAVLQSNTLRSCSQVLLGEH
WQMVLLDSQVAGVPHGELSQAQLNLLDTHLSAHPERHALVLLHHHPLDAGSTWLDQHKLA
NREAFWQVMARHPQAKIVVCGHIHQALDVRYQGARVMAAPSTCIQFMPDSHDFALDNQNP
GWRWLELYADGRVETQVARVTGQHFRPDFDSSGY
>D6JFH6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli B354|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A5J4DVH5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium MnTg02|TrEMBL
MQLYYSKPVLEAGRKSMRCTYISDLHLEFKALRDPLPEGDILILAGDITLAKCLDPKPTE
SKEIKLRDSTLAFFDEAREKFDHVLYISGNHEPYHFDIEETPKAIRKYIEGIIYLDDDLA
EIDGVTFIGATLWTDMDNENRRAILEISERINDFKIVSRGRDKFTPMDAVAKFRKSSTYI
ADAVSKLEGKPVVVVTHHAPSPLGLNEKECGNLLDGAFASDLHDLMEQNPNITNWVFGHT
HVRKTFQIGDTTCRANCRGYDTVSWNNTNEANGFDADTWFEI
>A0A1A9WQJ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Glossina brevipalpis|TrEMBL
MRNCITKIANIFRKSPLQNQLIHENFNEECLQLDHCEGDTNEDKLKVTRQRQHLTIVIGP
NGSTSWSDKHMAHGDNCEKDKRNAMSQRNITNDKADNKHCAARTTTETTLSLPIEKDKQH
CFRTKSQHKNKIRSKNIRTQTNFNQNQVQSIDSANGNEENGDQNFDLLVLQRGNEYPREV
TKNPNMILKELETHLRNNSNAAKITSACAEGFESVTKPMNCRVPDTKPAEEIDDEARMAA
EGADLVTPLPTSNTVRQYGFGRITQPELIDAIRNLDTHALHINNISLEDKFELLRRYEHQ
QKFARLPCRINMKSNLNVADQKQEDYHHHQHHHQSVQFENVNSEKNNCEDVILRRKSILH
PRSLYERRQPRMPKLKLIIKKNYLAEDNGSSLNNATAIILDFFYFLAFQLMHKGTLDQFS
SLEQSDMFIMDSIKDAFCPWEPEYELPYIVPPKLPLKGLLVFSKEDKILHLVEQACNRRE
IDISIARSLEATTEKLTSSPDIFHLIVIDGRYPNFLDASEIAKAIRLTQGYDYTTIAVLV
KRSFFENESGMTAFLEAGVNACIVECYHLPYLCMELRQIVLYTALNRVKDVVIITDNKFI
IQYVNQAAARLLGVLPKEATNKHLSEFFVSDLTQWTTALKPKDLTSDKPLDFAGTVSVKG
KNLESTSLNVRARQLACYGRITTHLIFNVDVPSIAQADSTVALSHTREIRSSLAGMRRSS
DLKGLTTESRRASAAKLAAMPLEAPITKIINLLSQLQENCSTDEALLIDRVLDFLKYESL
YSPQMKDIQMEDPIATELIGALITGSNVHSSRRSSNDSTIRTAITRPTASLISTMKTAPL
IMDALKESLTWEFDIFRFEKITEKRPLLYLGMELFDKFKVFTAMRVDQVVFKNWFVAVES
RYHAQNAYHNSTHAADVLQSIGVFLSHFSKKEMSMDCLEESSALIAAVVHDIDHPGRSSA
YLCNSSNPLAILYNDVTVLENHHAAYFFKLTLCDDSVNIFKNLETDVYKAMRNIIIDMIL
ATEMTRHFEHLAKFIVTIEEDSALLMRRMLIKVADVSNPARPHLFCVEWAQRIAEEYFQQ
TEEEKDKDMPIVMPMFDRCTCSIPKSQIGFIEYIVMDMLLAWDNFIDMPELITYTRHNLE
MWKHFEEEGVRTIADVKRRQAALAMRKISLK
>A0A4Q6XGR0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter halotolerans|TrEMBL
MTFQVSTSSQQDFVMIQITDTHLLEYPHLEFVGMQPELSFRAVIELMREQHPQIDLIVHT
GDLAQTPTPVTYQRYIQHMQSLGIPFFHTPGNHDDVAHFPFHHADQTQPTVIELGKWSII
LLNSAQPQRIDGKVADIQLKQLTELLPQLQDRYVIIACHHHPFAMQSAWIDQHKLKNSSD
LLEIVKPFSNIKAIICGHVHQDSIQTWHGIEFLSTPSTCIQFKPKSDKFALDEEHPGYRY
ICLKANGELETQVYRLSTSERLISSEVLGYD
>A0A5E4IF14|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKLSMILLASILCLSVASQAMNDSATTGPYKVSFDPGVPHDAHNITVSEPKAEESLGQSQ
LEGYPIASDVFTTLQKTVVPDSIPSDSEKVLPYEVSKYKQNGYGTWHYGPGIVSVKRLDI
MPTNHSGASATKASRLLNFFTITDIHITDKESPAQAIYLGYKGGSSSAYSPVMLYTTQVL
DAAVQTINALHKQNPFDFGISLGDTCNSLQYNELRWYIDVLDGKNIKPDSGVKDDPVPGP
YNDYQDEYKAVGLNKTIDWYQALGNHDHFWTGFLPPNDYIRQTLIGEDILNLGNPFIDPR
GLDSRGFYMGSIDGRTPYGDIIGVGPIKDFKNPPKVLAADPNRRALSRKEWISEFFNTSS
SPKGHGFNQSNIETGFACYTFEPKSNIPIKVIVLDDTQRDDDLNNPDTLGYGHASLDNER
YDWLVKELDMGQAQGKLMVIAAHIPIGVEPAGSMMGWNPTSPISEAQLIAKLHTYPNLIL
WIAGHRHSNTVTALKSPDAAHPELGFWEVETVSLRDFPQQFRTFEIVRNSDNTVSIFTTD
VDPAVKDGSLAAISRSYGVAAQEIFNNSIGLLPTGSYNAELVKQLTPEMQAKLSNEIGKY
PLITET
>A0A5E4K353|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKKRDKIILGAIVLLLVWIIVWNILPVGTGNWNERQIQQIQSVNSSDHFCFAVLADNKNG
FKTFDQIVEDINKRKNFVFAIDVGDLVYDGEKEKYRIFYNEMSEANLPFLVGIGNHDITE
NGRANYFDIFGNFYYSFSYNNSLFIVLDDANQKDIDSQQMAFLESELKKDFANKFVFLHV
PPFDPRGYVFYLGANRTAEHSLSDKENAQKFIDLVSKYNVTTVFTSHIHAYFNETKENVS
YIITGGAGGEILPSDPNHYFYHYINFCVNGNNTNYEIIKFPSPKPNSFSRLIHSAWLYSW
YYIVVHRYEIAIVILMILLVLDAFYLQIKDFLKMRRKKK
>A0A5E4J4I6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MNLALRYTIFSVVVLALSLGLHYWLLNSIYTYFDWNMNVAFHIVVFCLAIIFPLGMTLQN
AIDSKLTRTIYWFASAWLGCVILVSAILLTTQIISLIFFIPEEIKGLVVIASFFLCVCAF
LYARMIKIVRYTLKSSKIKKNLRIVHLSDLHIGPIYRESNLKKIVQITNSLKPDLVAITG
DLLDGTARYRELDLLKPLNNLKAPAYFVFGNHDFYSGEEKVLRLLKATKTKILRSKLVET
KGIQLIGIDDSENKHHAPAELKKIKFDKKKYSILLYHRPQGLNKCSEEGIDLILSGHTHG
GQLYPLILIDKLFNEYVKGMHQYKNTKIIVSQGVNTWGPPMRMGSQSQIIEINLQPQ
>A0A5E4LVI3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKILAFSDLHHDELALESLTQLAKKHDFVFICGDISRTEIFADSVLHAFPNSFIIPGNWD
SEHVNTIFSSTPNWVHEKRAEIGSGLNVVGFGFSPPTPFGTFGEISEQEIFSRMSKLKID
GNTLLLLHTPPKGYFDEALFRHIGSASILKIIEEKKPLAAFFGHAHEQIGTAMLGPTRLI
KLPPANSMRACSLTIKNKKITSEFINL
>A0A832M2G4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oscillatoriales cyanobacterium SpSt-402|TrEMBL
MRESSLLVAQITDIHLFAESDKCLLGLKTLESFQAVLYQVKDLERQPDLLLLTGDLSQDG
SAESYEMLHAMLEPLGIPAYWVPGNHDKPAVMAEVLTRSPISHQKSFRAGGWRFLLLDSC
VPGCVHGVLSPESLSWLDTELSQQPDEPTLIAFHHPPFLVGSDWMNDIGLLNADELFAVC
DRHPQIKVVLFGHIHQEFHQNRNGVDYLGTPSTCIQFKPNSPQFSLDEEQPGLRLTTLFP
DGTWQSSVRRTIYACEPDLAAVGY
>A0A379B322|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|[Pasteurella] mairii|TrEMBL
MFNTYVYSTEEQVIRLVQVTDTHLFKDINGELLGINTQASFNQVLSEIKQSNFNYDLVIA
TGDLVQDSSDEGYFHFCESVKQLEKMVFWIPGNHDFQPKMFDILNREQENICSKKHILLG
KHWQILMLDSQVYGVPYGQLGQYQMDWLLAKLKEYPERYSLVVLHHHILSTNSAWLDQHN
LRNSYDLAYALSPFNNVKGILYGHIHQEVEGEWNGYKVMATPSTCIQFKPDSNNFALDIL
QPGWREISLHSDGRIVSQVKRIQNATFLPNMLSEGY
>A0A2T3L3G7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium indicum|TrEMBL
MQTYFLPQTNPNSVVLLQITDTHLFADESGCLLGVATKDSFNAVIDAVDASARPFEAIVA
TGDISQDHTDESYQHFSDGISRWSQPCFWLPGNHDYQPAMHSVLPSPQIKSCEQVLAGDY
WQVILLDSQVQGVPHGELSEAQLLMLDATLKAHPERHALILLHHHPLVAGSAWLDQHQLH
NNEAFWQIIDKYPKVSAVLCGHIHQELDCVYHGVRVLATPSTCIQFLPDSNDFALDKTNP
GWRYLELTREGQLNTDVCRLQGRRFIPLFNSAGY
>A0A508YGG7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Limosilactobacillus mucosae|TrEMBL
MIKLAVSSDNHLDVNRIMSTRALHIQASWLLRHDIDYYLYAGDLYNNFGRTRRYFAALQR
LVGERVQIYYVLGNHDMLSHASYQDVEHLADPMYLHNQYVDLPGTDWRLIGNNGWYDYSF
SDYAQQPQRVAQWKKVYWVDAAIKQPMSDQQRMGLVLNQVEQQLTMAQAAGKKVIFLTHF
APRKALLSPKPSFVQSQRQLKTYQMINAMMGSERLGRLLEKAPHVKYVFYGHLHGIHDPL
KAAHLVYLNQAVGVKKAKRTEWQYDKFAEQWEHRLKIIELNN
>A0A2R4NW00|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia massiliensis|TrEMBL
MESLFKLPMASGAKVRILQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGIARLPAPCLWLPGNHDFQPAMVDALADAGIAPSKQVLVGD
NWQILLLDSQVFGVPYGELSDYQLEWMERCLVAHPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTIDTVA
PGWRYLDLLPNGILETEVRRLASDEFSPDMDADGY
>A0A249WJE2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella michiganensis|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFTAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQVLLMDSQVFGVPHGELSDFQLEWLEQKLTEVPQRYTLLLLHHHPLPSGCSWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A7C1RRJ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter sp|TrEMBL
MSSQKITRPLRVLQLTDPHLMASADGALLGVNTRDSLDAVIAQVLKAHGQPDLILATGDL
AQDGSEEAYRVLGDRLGAFACGSAWLAGNHDHAELLGQVAARYGADRRHIVQGGWQFILL
DSSVPEKVFGELAQAELDFLAERLGQHPHLPALVTLHHHPVDIEADWMSDIGLRNRADFW
RVIDRFPQVKVVLWGHIHQAHEQCRNDVQLLATPSTCIQFTSGAREFSVEDLAPGYRWFE
LQASGDFTTQVCRALDFDFELDKNSAGY
>A0A3M1GJX4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Planctomycetes bacterium|TrEMBL
MAATDAVRLLQITDMHLVADRAGRVRGVCGHESLGAVLAAARSRAHVWPPDAVLATGDLS
DDGSAASYRHFRERVAGLEAPVYWIPGNHDDRAVMDEVLPGGNVMAERSLRLGAWQIVLL
DSQLPGEVRGRLGVRELARLDAELGGSDRPHALVVLHHNPCDIGSRWFAPLGIEDEAAFW
EGIERHERVRAVLFGHIHQDFERVRGGVRLLASPSTSAQFAPGTDTLVIDDRPPGWRWLV
LHPDGRVESWVERL
>A0A5N7TZQ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIQQILKQHPEADAIIHT
GDLAQAPTPITYKRYISFMQTLGLPFFHTLGNHDNVDHFPLHNENHQEPVVVGLGNWRII
MLNSAVKGKVDGHLSLEQLENLENLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFKNVKALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLNNDGTFETKVFRLENFETHINTDISGY
>C9QMW5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio orientalis CIP 102891 = ATCC 33934|TrEMBL
MKVTSISSDQDSIKLLQITDTHLFEPLDGSLLSVKTLDSFHAVVDAIVDSGASFDALLST
GDISQDHSAISYQHFEQGIEKLELPCFWLPGNHDFKPSMNSVLPSSQIQQVEHVLLGEHW
QIVLLDSQVVGVPHGFLTEQQLTMLDEKLSEHPERNTLVLLHHHPILVGSRWLDQHTLKE
ADSFWRVVEKHNNVKAVVCGHVHQDMNVMYKGVQVMSTPSTCVQFKPNCDDFSLDTLSPG
WRELELYNDGSVSTEVKRLKPGSFQPDFNSAGY
>A0A1B7HV87|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Buttiauxella gaviniae ATCC 51604|TrEMBL
MESLLNLPVAGGGQIRILQITDTHLFSGKNETLLGINTWMSYQAVIDAILAEQRHYDLIV
ATGDLAQDHSAQAYQHFVEGIAEIPAPCVWLPGNHDFQPAMFSSLLEAGISPAKQVFLGD
SWQILLLDSQVFGVPHGELSDYQLDWLERKLSGAPERHTLLLLHHHPVPAGCSWLDQHSL
RNAAELDNVLQKFPKVKTLVCGHIHQELDLDWNGRRMLATPSTCVQFKPHCSNFTLDTIE
PGWRWLELHPNGEVTTEVCRLKGAVFNPDTASEGY
>S7PWD9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Myotis brandtii|TrEMBL
MSSHFLGVVMGGAAVRPTSHVQFGPMRFHADQLQVLSAFIKDVGPMRFHADQLQVLLVFV
RDDSQCKGFRKACEKAGFKCTVALEVQAVLTCFLAANHDIIIIDHRNPQQLDALTLCRSI
RATNVSENTVIVGVVCRRDGEESVMSLISAGFTRRYVENPSLLACYAELLQLEFGEVRSQ
LKLRACKSVFTALEKSQDAIKITSEDNYIQYVNPAFETTVGFESGELLGKELAKMPLNEK
KADLFSTINSCMKMGKEWQGVYHAKNRDNVPQNVKIIPVIGQGAKIRHYVSIIRVNSGNS
KAEKIMESVQSDTPTDNQSGKHKDKRKSSLDIRSVASRASEVASQRRHSSVARIHSMTIE
APITKVINIINAAQENSSMPVSEALDRVLEILRTSELYSPPFGAKEEDPHTKDLIGGLMS
DGFRRLSGNEYTLSTKNLHQISGSLLASESLHNIPPRIAEAMENDDDWDFNVFELETATQ
KRPLTFLGLKIFARFGVCEFLKCSETTLRLWLQIMEANYHSSNPYHNSTHAADVLHATAY
FLCQERIKQALDSVDEAAALIAAAVHDLDHPGRTNLSLCNAGSALAVLYNDCAVLESHHA
ALAFQLTAREDRSNIFKNVERNDYRTLRQAIIDMVLATEMTRHFEHINKFVNSVVKPLAE
LEESEGSEPNPRDVDTMLRSPENRTLIKRMMIKWMMFKCADVSNPCRPLEQCIEWAARIS
EEYFSQTEEEKKLDLPVAMPAFDRNTCSIPKSQISFIDYFVTDMYHAWDDFVDLQELLQH
LDNNFKYWKGLDEMKLRGVRPPLEPK
>A0A026W1V4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ooceraea biroi|TrEMBL
MNRQQTLPVLYVCGATDDSNVHKEEPTWFSSILGACGRMRNKCCTRNRMQVAELSPQLMT
RIRKGPQDLDTYLLTTTVPSIILLVFNKDDQQMDILATAARRLGWSVSVAKDAEKAIELF
QNRAHELVIIDHRGQRADEADAICRMIRSSPVYHSSVIIALVKKSYFMIDEKDHIVALNL
LETGFTRALIECSHEGILINELVGIYTSSLLPKTQLAAAHALYLALDKCRDMVHVTNDKN
IVQFLNKVSEKLLGYKVEEMMGRNLSDIVYYENFTLMEQQLSKGREFEGNMNCKRKNNQM
ITINCRVIPFCTMLKKPTHYIYVYDTTYLSENSAPISPISSPLHPPQRTSILSSARKSSD
RSGISEAGRRRSSLQKLHSLQLEAPITKVITLLSNAVTDTTNPETAAQIDKAIDILKTTE
LYVPHLKEDRAMYSDPVTQDLVGALLASPRMSAWDSRRSSSDSARLATIKAITGTNNSRM
QITSFHAPQEIAEILEKSLDWDFQIFKLEVLTERRPLVFLGLAIMNLFRVPAKLNCDERT
VQNWLAIIEHNYNADNSYHNSTHAADVLQATAKFMQSKRLKEILEPLDEVAALVAAAAHD
IDHPGRSSQFLCNANNRLAILYNDLSVLESHHAALTFKLSLSDDSVNIFKNLERDTYKML
RQNIIDMILATEMTKHFEHLAKFMNVCSARIGENQETYSDSLDMSVVLQPDNVILVKRMM
IKCADVSNPTRPLRCCIEWARRIAEEYFRQTDEEKRLKMPVVMPMFDRMTCSIPKSQIGF
VDYIITDMIEAWDVFIDMPEMVGYMRQNYERWKEYNEQGISTLQDVEQLQQHPDLHIPRL
SN
>A0A2K6FT74|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Propithecus coquereli|TrEMBL
VAVAEVQFGPMRFHQDQLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTKEAQAVLACFLD
KHHDIIIIDHRNPRQLDAEALCRVAREELSVMPFLAAGFTRRYIENPNIMACYNELLQLE
FGEVRSQLKLRACNSIFTALEKSQEAIEITNEDHIIQYANPAFETTMGYQAGELIGKELG
EVPINEKKADLLDTINSCIKIGKEWQGVYYTKKKNGDNVQQNVKIIPVLGQGGKIRHYVS
IIRVCNGNSKAEKISECVQSDTNTDNQTGKHKDRRKGSLDVRAIASRSGEVSSQRRHSSM
ARIHSMTIEAPITKVINIINAAQESSPMPVTEALDRVLEILRTTELYSPQFGAKDDDPHA
NDLVGALVSDGLRRLSGNEYVLSTKSIQHVSSNIITPISLCDVPPRIAQAMENEEYWDFD
IFELEAATHNRPLIYLGLKMFARFGICEFLNCSESTLRSWLQIIEANYHSSNPYHNSTHS
ADVLHATAYFLSKERIKETLDPMDEVAALIAATIHDVDHPGRTSSFLCNAGSELAILYND
IAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQGIIDMVLATEMTKHFEHVNKFA
NSINKPLAALEESEETEKNQEAINSMLRTPENRTLIKRMLIKCADVSNPCRPLESCIEWA
ARISEEYFSQTDEEKQQDLPVVMPVFDRNSCSIPRSQISFIDYFITDMFDAWDAFVDLPD
LMQHLDNNFKYWQGLDEMKLRGLRPPRE
>A0A8F8A0G8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter lwoffii|TrEMBL
MSFQQSSTSTQPDWTIIQISDTHLMDREELEFARMNPEQSFHEVMQQIQQRFPQMDALIH
TGDLAQVPVEQTYQRYLEYIQSLNVPYYQIPGNHDDSQVFPFHQNANQVHAIHFGTWTMI
LLNSAVQGKIDGWVEQAQLDQLDQLLLEFKHQHVIVACHHHPFAMKSHWIDQHRLKNAED
LKDVLARHQNIKLVLFGHVHQDSCNEWHGIYFLSTPSTSVQFKPKSEDFALDQAAPGYRV
LHLQQNGEFDTYIERVALSQQNINTEISGY
>A0A2K6UBM3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Saimiri boliviensis boliviensis|TrEMBL
MPRSRQFKRILNRELTHLSETSRSGNQVSEYISQTFLDQQTEVELPTVTAEEPPKPVSQI
SGLHGLCQNASLSSATVPRFGVQTEQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAII
FSIFQSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSTKQRLSLRRMVIDMVLAT
DMSKHMNLLADLKTMVETKKVTSLGVLLLDNYPDRIQVLQSLVHCADLSNPTKPLPLYRQ
WTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPD
AQDLLGTLEDNREWYQSKIPRSPSSLTNPEQGGPDRFQFGLPLEEAEEEEEEGEEPALDK
EALELSDTELPPEASPDPGDLPLDNQRT
>A0A2K6UBK1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Saimiri boliviensis boliviensis|TrEMBL
MPRSRQFKRILNRELTHLSETSRSGNQVSEYISQTFLDQQTEVELPTVTAEEPPKPVSQI
SGLHGLCQNASLSSATVPRFGVQTEQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAII
FSIFQERDLLKTFQIPADTLATYLLLLEGHYHADVAYHNSLHAADVAQSTHVLLATPALE
SELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSTKQRLSLRRMVIDMVLATDMSKH
MNLLADLKTMVETKKVTSLGVLLLDNYPDRIQVLQSLVHCADLSNPTKPLPLYRQWTDRI
MAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLL
GTLEDNREWYQSKIPRSPSSLTNPEQGGPDRFQFGLPLEEAEEEEEEGEEPALDKEALEL
SDTELPPEASPDPGDLPLDNQRT
>A0A223YW71|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methanothermobacter sp. EMTCatA1|TrEMBL
MVLIAHISDLHVGAPNFKEDILLEAIRQINKLKPDATVITGDLTDNGYYLEFLQAAEYLS
DLKGPHIFVPGNHDARHVGNETFEDVFRYRRGTFVMDGLTIIGLDSSEPDLDYGKIGRSQ
QVWMEEELDRASSRGHIRVIALHHHIIPVPKTGRERNVLADAGDILQSIISKGADLVISG
HKHVPHVWRLENTFFVTAGTVSSLKLRGKDINSYNTYYIDEDSMRIVLNQVQGESIELAA
CSL
>A0A182FGD7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles albimanus|TrEMBL
MKAFFRKNKSKSMESLYKPPPAKCDVLTVKQLHTFPQTSEQTPRTHRRYSLFGTRSSSNT
TPSTEETPSTEPSSSTGSKDRSASVGQPIATWDFEAPVNLVTLLTPPADDEHVFEECDDS
HRMVNGRDSTPPIATAYQRHPARPMNLSPDWMPQDREYAAVDETGGEHRLHSPASPTSTS
SSPHVFWPRAYGRRSHHSWRPAAAFEEILEEPRDESPTLSGREWRRFDAFRCLPVDAIDP
ACRQQVLANYDVQFYEYEAGEAHHPEPSEPPAVTVSSEVAPSTSVGGKGSSPSDQKPDEH
QLAETTPLGTTVQEERLQQAPYLPSIKGYYEGILALSNELAEKISEVVKRLVSDLKFPNL
LPPNPAIKILIAFCKNDPVFEALVNASHRLSFEPTFVKSAEAAIDAFQNPTAGGHHIIIV
DARYPRIIEAEALGRSIRNSKGSQHTTMVAVVKKSVFEKDDTAVISLLDVGYNRCIIESP
HVSICSSELRQIQHSLVRPQNVISTQQALYTALHRSREAVIITDDTLRAQYANRASERVL
NMKLDEIVGRSLGDLVTADISNILSHTSRYKDYDGYLTTRRKSQESSQIHVRAVPVSCIG
RNPTHLVLILESSASALASISAAGEALQTLPQGKEVARGSLHSIRRPSFDVRSIASDGLR
RTSLVKLSSLPLEAPITKVLSLLAQVQENCSLEEAKLLDRVMEFLKREGLYSPQMKEIRP
DDPVATDLIGALLTQGPTNILSSRRSSNDSIIRGGGRPSTGSIVFNKTKESSLLSDLLHT
ALDWDFEIFKLEELTDKRPLVCLGLELFRRFDVYNTFNCDEMTFKLWLIEMEKNYHSENT
YHNSTHAADVMQATAVYLQQLSNRELKIMDRMDEATALIAAATHDIDHPGRSSAFLCNSD
DMLAVLYNDICVLESHHAATTFRLTLADDKINIFKHLDRDSYKLARSIIVDMILATEMTR
HFEHLAKFVSVFGTDVESKEPLPPDNDDNQILVRRMLIKCADVSNPTRPLRFCVEWARRI
AEEYFMQTDEEKRKALPIVMPMFDRTTCSISKSQIGFIEYIIHDMMDAWNSFIEMPEIIR
YMEFNYSQWKLFEEQGINTLSDIKRKQLSLAEEPSSIISLEEKF
>A0A8G1D7N2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. 2hn|TrEMBL
MHVVQLTDAHLFADPAGTLLGLNTRASLGHVIEQVRREQARIDLLLCTGDLSQDASVASY
HAFSELTSKLGAPARWLPGNHDEAQVMQTVAPELVQAVTDIGQWRIVMLDSAVVGATFGL
LADDQLAVLDQALDGAGERHCLVCCHHQPVDIGCAWIAPIGLRNADELLKRLRSYPQVKA
LLWGHIHQEWDEERDGIRFLATPSTCIQFAPRSEDFKVSEEQPGYRWLRLHADGRLETGV
ERARDFEVKLDFDSPGY
>A0A1B8QXU5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus sp. CCUG 60358|TrEMBL
MSNTFECEPESEIVKLLQITDPHLFKDTSKELLGINTHESFSQVLKEIQAESFDYDVVFA
TGDLVQDSSDEGYLRFIEMVKPLNKSVFWLPGNHDFQPKMVEHLSQPPINASKHLLLGKH
WQVILLDSQVSGVPHGELSAYQLDWLKMKLAENPARHSLVVLHHHLLPTNSAWLDQHNLR
NAHEFSEVLAQFNNVKGILYGHIHQEVDGYWQGYQTMATPATCIQFKPDSNHFALDTLQP
GWREIELHPDGRIETRVKRIKQKTFLPNMEEEGY
>A0A7Y1GEI4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. WS 5414|TrEMBL
MPSVSALTADDSVLLVQLSDSHLFADADGTLLGMNTADSLQRVIEQVLAQQPRIDLMLAT
GDLSQDGSLESYQRFRQLTRQIPAPGRWLPGNHDEPQVMQLATQDSDLLEPVMDIGNWRI
TLLDSAVPGSVPGYLQDDQLQLLARSLSEAPERHHLICLHHHPVSIDCTWMEPIGLRNAE
ALFAVLDAFPQVRALLWGHVHQEIDRQRGAVRLLASPSTCIQFEPGSDDFKVEEQVPGYR
WLRLWPDGRLETGVERVLGYEFTIDYGSNGY
>F9GMA2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus haemolyticus M19501|TrEMBL
MKNAFVYQTEKPVIKLLQITDPHLFKDESAELLGINTQASFAQVLKEIQQENHEFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTQVKRIQQAEFLPNMQEEGY
>A0A2S9YP83|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enhygromyxa salina|TrEMBL
MMRAGSPGTLLHAGLALGLASSLMGCTETECATPDYTRAECRVLAENGFARLLSSSGVEL
RFQAPGATDPSASYSAEGIVVERGAAIHARVAHMGEFALSLRNPANQARTLELELSNVHP
LATLEDNPQIIQQPLVGTSTTRQLLVTVPARGETWVRGGLSHASACPPVFRLAVLADIQT
NPTQFARIIERIHKEAGLAQAAGELLAGVVVAGDLTESSTEDEFGVFQGLLESSAVPFAL
TPGNHDVYDSHMPFYNQNFGPGNYAFDVCGAHIAMLDTGSGAIAESVVGRLPELFDPGDS
KYSLTVMHHPPHPGLTGGGWSREDLAMITLGEFVHQGGDLVIAGHAHMLREFTDLSVAGG
TVREIIAGTAGAWQGAGQPIYGYVRLTFAAGEIDACFVEVPPPGGVPHVETPTSIPVCDE
A
>A0A7V7GTW8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas laoshanensis|TrEMBL
MASPVTMQAGHVCVVQLTDSHLYADPDADLLGLDTHASLQAVIDLVLDEVPSMDLVLATG
DIAQDGSAAAYQRFSHAMQRLPAPCHWIAGNHDDAELMQQLGEASGFSREWVDLGNWRIV
LLNSNIPGAVAGHLAAAELAVLDRALAGAGERFVMVCLHHHPVPIGCGWMDPLGLLNAPE
LLNRLEVDSRIRLVLWGHIHQHFDQQLGHVRMLASPSTCVQFAAHSENFATDERAPGYRW
LRLFDDGQVETAVSRLAEGRFLPDPGATGY
>A0A1X0VWJ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rouxiella silvae|TrEMBL
MESLFKLPLVDGAKVRILQITDTHLFAGEDQTLLGVNTFRSYRAVLDAICAQQREVDIIA
ATGDLAQDQSLEAYHHFSRGVNRLPAPCVWLPGNHDFQPAMVNALAEAGIHPSKQVLLGN
DWQVLLLDTQVFGVPHGEISEYQLEWMTRCLDAQPTRFTLIMLHHHPLPSGCTWLDQHSL
RNAHTLANALQAYPKVTTLLCGHIHQEMDVDWYGKRLYATPSTCVQFKPHCTNFTLDTVA
PGWRYLTLHPDGRVETEVCRLETNEFSPDADAEGY
>A0A7J7AP27|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lamprigera yunnana|TrEMBL
MGCSPSVLLDHIQGESVSSNPEKQITTKQTSILNLKKDPTCIVVRRKSSLPLTPEDEPFD
AYRNPNEIKLGLLLPPNRSPLKLLMVFLQTDAVSDSLSRAADKLGFDVTFCDSYDGALEE
FLSKLHDLIIVDTRCASKALDYDTLCRSIRNTKGSHHTAAVAVVKKSTFDKDDVTVLSLL
DAGYNRCIVETTNVVHCVNELLQLKHSDMRPLAHASTNQTLYASLEKCSDIVFITDDTFR
LQYANRASERILGYRCDETLGKTIQEQLIYDGIQMNSMSSSLMRAKEWQGPISLRRKGQD
GITFTCKAVPVACAGRVPTHFVMVMDNHGIAETMSCLDKPRGSVQSLRRVSIDVRSVGSD
YLRRTSLAKLSALPLEAPITKVITLLSQAQEQTSPTVVSILDKVMDMLHSSELYSPHLKD
DLKLRSDEPVTSDLITALLMQQPQLHTSNSSRRSSNDSMTVRTGPRGVSKLRVPSQIRDL
LETSLTWEFDIFRLEELTNKKPLTHLGMNLFAHFDVSATLNCDEKTLFNWLTVIEMNYHI
DNSYHNSTHAADVMQATAGFLEKDRLKAIMDPLDEATSLLAACAHDIDHPGKSSAFLSNC
DNPLAILYNDVTVLENHHASLTFKLTLGDDRVNIFKHLDRDTYKIARHNVIDMILATEMT
KHFEHLAKFVNVFCPKNFRSDMESECVSISSPENITLVKRMMIKCADVSNPTRPLRLCVE
WARRIAEEYFAQTEEEKSKGLPVVMPMFDRITCSIPKSQIGFVDYIVNDMFEAWDAFIDM
PELITYMRQNYIRWKEFEEQGHTTAADIRKLQNTLIMGPVFSNKPSTKRNE
>A0A8F8GKF3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter septicus|TrEMBL
MSFQVVPTSAQEYVLIQITDTHLLEQPEHEFVGMNPEQSFHEVMTHIQQHYPQADAIIHT
GDLAQAPRPKTYQRYLHFMQQLGIPFFHTPGNHDDEKYFPFHQENPQQPVLIELGDWRII
LLNTAVSNRVDGLVSTSQLEQLTDLLEQHQAHPTILACHHHPFEMHSKWIDQHKLKNSQA
VFNLLERFKQVKAILYGHVHQNSSNFWQHIECLSTPSTSVQFKPCSEQFALDAVAPGYRV
LKLKTNGTFETVVQRLEHINHLINTEISGY
>A0A2H5X3S6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR16|TrEMBL
MAEVLTVAHISDTHLGYRSLSKEDPRTGVNQREVDVYHAFAHAMKAIQEASPDLVLITGD
LFDKKVPSIWSLRRAFRVLRTVQESRGGKPLILLGGNHDTPRTRESSAVFPLFEEIPGIK
AVYGMPEQVQLPELNASVMCVPAASAARLADENLKPEPDERFRFNILAVHGVLQGLFTHE
YTPFFLPMSRVLDERWDYIALGDYHDFRKVSRNAAYAGATEFTTTNIWSENREKGWVWVE
IEKGKPPLIRHRTVTTRKVLSLPDVDASQCASAEEAIETVLAEAQQDEVTGALVRVRILN
LPYTERARVHRAIVEKMADAFHVQVDFRAAPLTAPSASGQQTGTGIAQPIEERWRQFVEE
HKEELPAEIGAEEVISRGLQALGAVGEVTSP
>A0A7W4GJS1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. SG41-7|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIKPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAVLCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTQVRRLPNGQFSPDFDAGGY
>A0A448JXU7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurella aerogenes|TrEMBL
MLNTYVYSTNDSVIRLVQVTDPHLFKDTNGELLGINTQASFNQVLSEIKQSNFNYDFVLA
TGDLVQDSSDEGYFHFCESVKQLGKMVFWIPGNHDFQPKMFDILNREQENICSKKHILLG
EHWQILMLDSQVYGVPHGQLGQYQIDWLLAKLKEYPERYSLVVLHHHILSTNSAWLDQHN
LRNSHDLAYALSPFNNVKGILYGHIHQEVDGEWNGYKVMATPSTCIQFKPDSNNFALDVL
QPGWREISLHPDGRISSQVKRIQQAKFLPNMLSEGY
>A0A829IXZ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli KOEGE 73|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A4R7GCQ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rahnella sp. BIGb0236|TrEMBL
MESLFTLPLVNGAKVRILQITDTHLFAGEDETLLGVNTFSSYRAVLDAIKAQQRDVDIIA
ATGDLAQDQSVEAYHQFARGIGELTAPCVWLPGNHDFQPAMVNALQDAGISPSKHVLLGD
HWQIILLDTQVFGVPHGELSEYQLEWMERCLNAYPDRFTLLMLHHHPLPSGCTWLDQHSL
RNAHMLANTLVNYPKVNTLLCGHIHQELDLDWYGRRLYATPSTCVQFKPHCTNFTIDTVA
PGWRYLDLYPDGRVETEVFRLETSEFHPDTESDGYE
>A0A6P7NKE7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Betta splendens|TrEMBL
MAQQAGMGVTHQDTLAVPPMPKHSGLNEDLVKILRENLLQPERPRGHRRSPSSISPRLSP
RNSPRLLRRMLLNNNIHKQRRFTVAHTCFDVDNGTSSGRSPLDPMASPGSGLILQANFVH
SQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALT
NIQQDRASNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEM
ASNKVRVTKCLTLTGLDKTFNLQQFHL
>B4I8R1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila sechellia|TrEMBL
MGCSPSTLPPAPSAGQTGERGSLPLDASEKDESRLFCIKLRRSRLRRCSCGGVTLQPPSD
GNGSTAGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHSVVRRATGSTG
TSGTSSSGGNSRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLVFH
KSDSICEAITAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSFKNLDAEH
IARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQIL
HSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLE
DIFVSDLSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVP
GGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKII
NLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYS
SRRSSNDSIIRTGSSTRTAAIVPAKMKSNPIIMELLDESLSWDFDIFKLEEITDYHPLLY
LGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLT
NKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITF
KLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPRDHNP
QTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMF
DRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLAEI
MAKQPPVGKMANSK
>U7R6Y0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus temperata J3|TrEMBL
MESQFKLPVVEGTTAKILQITDTHLFAGKEETLLGVNTYRSYHAVLDAILKQNADIDLIV
ATGDLAQDQSLEAYRHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGE
HWQLLMLDSQVPGVPHGELSEYQLEWMKKCLDMYPERYTVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQGYTRVKAMLCGHIHQEMDLDWNGIHMMATPSTSVQFKPHCTNFTLDTVA
PGWRYLELSISDRGEFSLTTQVHRLESNEFCPDLDSDGY
>A0A1S9CWZ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chromatiales bacterium USCg_Taylor|TrEMBL
MEKELSTMKDFRPNSIRDPRTVLQLTDPHLYADPGGLYDGLNTSESLRAVLTLAQARQWP
PDALVLTGDLSQDGSRAAYARLRECMGGLGVPVYCLPGNHDDKDAMRQVLPGGNIHAVDH
ARVGEWRCVFLDTAVAGREHGHLSAEQIARLDERLSAETGHPALVFMHHHPVAIGSLWMD
EIGVNNSPAFFKVLDRHTQVRAVLWGHIHQEFAGLREGVQLLGTPSTCVQFAPRTDRHQR
DTLSPGYRWLRLWRDGRLETGIERLEH
>A0A4Q4A5F5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFVGD
QWQILLLDSQVFGVPHGELSDYQLDWLETKLAAEPDRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLAKFPRVKHLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLAGAEFRPDTASEGY
>A0A845T8P2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteus sp. G4468|TrEMBL
MESQLELSVDQQHTVRILQITDTHLFANVDDTLLGINTYRSYHAVLDAIKQQGLSIDLIV
ATGDLVQDQSFAAYQHFADGIARLPSPCVWLPGNHDYQPAMIDALNQAGILSAKQVLIGE
HWQLLLLDSQIQGVPHGELSDCQLDWLTRCLESHKERDTVILLHHHPMPSGCTWLDQHSL
RNSHQLAERVKDHPQIKMMLCGHIHQEMDEMWNGIRLLATPSTCIQFRPHCTNFSLDTVS
PGWRYLELSLSAQGKRNIDTQVHRLAGKDFCPDLDADGY
>A0A851G3X8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. SECR19-1250|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQEAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPARHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLAKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLAGAQFRPDTASEGY
>A0A520S6G2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|OM182 bacterium|TrEMBL
MMPQTANSPIHLVQITDTHLYGKATGTLLKMNTHDSFEHVIELVRGKEDRIDLILATGDI
AQDASESAYGHFADRVGTLGAPYRWIPGNHDKAEVMKNAAATPDVDEKSVQINNWLILML
DTSTDGQVHGNLAPGELEFLHSQLQESKLNNSIEHIMICMHHNPVKGNSGWMKDIGLKNR
ARFWELAETATKIKCVVYGHIHQELDFVHGNIRCLCSPSTCIQFKPNVVNFALDQVNPGY
RSFELHANGTVESEVHRVEGENFEADFSSGGY
>A0A644VM69|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MYISPNSLVKLLLVILFTSILHGCEKIDPIPDDPNDPGQTTFIRDVIIPSQMSLVKGNSQ
AISGKGFATGDEIVFKTGDEEVVVNIATFTNTYATFIVPDELTNGQYKILVQRDQKRQEL
GTTTITIILNFNVPDKQGATIKGAVYCGTSPVQGVRVSDGITTTITDENGFYWLNSNKLH
GYVFVCTPSGYQSKTTNNAVPGFWSTLTAASTTTEQHNFELIEVQQRNHVLLIATDMHLA
NRGPSSNNDMAQFNNGFMIEARQFVESQPDKPVYTIVLGDMSWDGYWYSRNYDISNYVAT
VSSFPAPMYHVMGNHDNDPYHANDFDAEKKYKRALGPTYYSMDIGDVHYIFLDNTIFINT
GGLLGTVGERNYEKYLTNSQLNWLKDDLAAVKDKNKPVIVSFHCPSTSNYNSTFTTQLTF
NPSYKATEFHRCFDGFTNVHFLNGHTHNNGYTTVGTNIQEHNIAATSETWWWSGKTTGMN
VCIDGSPSGYAVFEVNSQDIKWYYKGIGLSKLKQFRTYDMNSVKAFFSQSEVSAVMEKLS
GNRKDDYASLVNNSVLINIWNYDPAWKIEVKENGNKLSTKQVYLKDPLHTIAYDYPRMRD
NGSVTDGFTTGNNPHMFQVIAASATSTLEITITDRFGNAYTETMTRPKQFVLSME
>A0A644VM06|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MPATLFKKLKLKIINFHNHISYFFGMSLIKYVGVLLLVGGLCMSGLSAQVPTASFVITGK
VSTPENTGIANVVVSDGYHVTTTNTDGQYSLNSNNLAKHVFISVPSDFKVPHEGNIPRFY
KSIKGTTSNITVDFTLTKQGKDEHLVLTVMADPQAQIAADMKRFTAEATPHIEWLKNTYP
RDVTFIGMTAGDLLWDAPAMYPDYVKAFQKLSFPFYQVIGNHDHDEKTTGNDYAASHIYE
SYFGPTYYSFNRADCHFVALDNIIYNTRPDYKEEITQEQLDWLQQDLSYVDKNNLIVVVM
HVPAYKRNGSIGVTNLGKLINILNGYKVVFISGHTHRMNKTVINRDMVEYTLSPTMGDSW
AGDVNVDGCPNGYGVFEISGNKLMNHYYMSTNRARDYQMRVYPVGAVTAFSNSIVANVWN
YVPGWKVEIYENGVFKGNMIKTTGYDPVAYNYYIGSSKPARKPGSEPATTPTLFYYTPND
ANAEMKVVVTDDFGNIYTEFLNKMPDKNDNRQVFFTESMGEGSATSPFPTVLEWTGWHNS
NITISAGDCPNQPDVRSTVVSATATSTYPECSGSNNVYFKAEEPGANRGFAINGIDASAF
KNIQLSFGYSKTSSDVRSDLEVYYWNGTSWVQLFFLFNEIFQPSGWYRSPIFSLPEDAEI
DGLGLRFVKPATSTNSIRIDDVWLTGEPRISASPVVNEAADVNSTGFTVSWDSYPIATNY
LLDISERENFAVADSTVLAAWTFPEIYAAGAVAGPHIFTANNKDKFISCTATGNDSNAIP
YGAGDGSETNPYAISSTGWENGVYKKYFQIDVNTTGYSGLTLSSWQYSSANGPKNMKVQY
RLSDTGAWIDVPNSDLVMPNAAYGPTSMLTDLALPTACDNQENVSIRWTMTSSMRTSGLS
TYIVTSGGTSRIANIYVKGKAVDAVSGYQSVAVSGTSHVVTGLEENKTYYYRVRATDGIC
VSNASEVKQVITTATSLKSVLNEQDVQVYYNPLNDCFEVKAVPGITGIAISVSDMSGRKL
KQKELTGSERSISVNHLPAGVYVVSLLVDGQCYTRKCVK
>A0A645CFI3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKILAISDPHGDYSKMKKIIEKAGDFDLAVVVGDITNFGPDEKVHELAEMFDKPVLAIPG
NCDQKSILKALDTSKAINLHGKTEQIGNIRFIGLGGSNPTPFNTPFELSEEEIENALEGM
VCSAENSGECGTIVLLTHAPPHGARDELPFGHVGSTAIQKFLDRVDLIVCGHIHEAKGTE
KAGKTVVVNPGEACKGSCALITIEETEKKPIEVEFVEV
>A0A645DYU8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MTAWAILLIAAGLGILTVQGVVFAMLRNDSAPLLPPAGLTLQPERKAFTVAVFSDFAGQI
DSVEKIGGDISRNDVAFTLCLGDIVKKRTALDFLHVTGEIRECMPCPVYAAPGNWDRNDV
TGWETYRAYFGQDYYFFGYGDTLFVALNTADGNLPEEQRTFLAQTLKRERPHFRRCVIFC
HIPPKDPRPEEEHAATPDFSAIFEDIIRPYRIDLILCGHIHCFTESEMAETRLVTTPSAG
QEIREPDNPMFGYLLLDFAADGAIGIRRVDVTPDTGREEMEYFFTVELCRIGWFVGAVAA
MIAGIALLPRGGRKRAKPPESGNQ
>A0A645BU70|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MNDRVFERRFSGHPAFWAACAAIVTVIYIYIFLTINEAQPEGTAGVIWLMLCFAMTGLSY
LARRTKRLHHAQLRRWTDRAGSLWLLFVLYAFFTLIALETAGRFLGGGLPAWAELAASFA
LSLCLIALGVKQAHTIQTTKITVETEKLPPGEERLRIVQLTDLHLGPYTGVKLLAQILRR
VREADPDMVLVTGDVADGSLEGRGREIAMFRRIRPKYGVYAVTGNHDYYDGIDKALEFMR
RAGMRVLRGESVCAGGIVVVGVDDRDHLCEDKWGLSRSETVIVNTKSRFRDKFILLLRHR
PVVEIGTQGLFDLQLSGHTHGGQLFPIISSRLFFRGHSRGFKKLKNGSMLYTSNGAGYVG
PPVRLMAPPEIVVIDLVRK
>A0A644YSQ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKRIFRALTVLLTGLFLFGLNNQKDEERTVQSIAPLVGKDENLKIWMVTDIHYLSPDLFD
DGEAFARMKATSAGKDLEHVPDMMEALVWEAAKEQPDLLIVSGDLTFNGEYQSLVELAAF
FERIEKNGTQVSVIPGNHDIHSGWARKFEGEEMAVVEQATPEDFQQIFADYGYDLAISKD
PESLSYVMEPKAGFPFLMIDTNIYSETKSTKAPKTEGRIKEETYAWLDEYFALQEEHLQT
IQLVGHHPLLNHTGRLGGGFILENAEDATDYFAGKGVQTSFAGHIHAQDISEATDREAPF
YEVVTGALSIFPNAIGEITLTNEELAYQRKTLDIEGWAEVTGVEAPELLAYTQTSHDLFK
RDGENLALQMMFEEQWHEEIYEEAVMDYVGKMNVRFFSGEDYVEDERSLGEWTSHAGYQI
IQQNSDNFLKKYTNQLLQDKNLDDRHIVIPQRQ
>A0A644YHD4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKKFKLIIITIIMALIIGVIAFIYINKPKPIAKITQVSTSNADLTFAVLGDVHENIDHFQ
EAINDLYIINPSMDALVLNGDSVDQGLDKQYDSMKNVLKKNNDLLPKTIIKNIGNHEFFD
YNIETNSAEQVESFINRYLEFSGEEKVYHDTWIKNYHFISLGSEDGNSETINSVTAFISN
EQLEWFKEKLAEDYQKGKPIFVFLHQPLDYGNGSWIGIKQSEEIKEILSQYPEVIMFASH
THRNLEEDSIVLDKPFTIVNTGAVHYTIIRDANSEGGRRIESDYIKGIYIEVNGNNVTIK
GRNIKEKQWIFTKEINKQ
>A0A8C5U609|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Malurus cyaneus samueli|TrEMBL
QASPGAGLSAGHLQPRPAPRVLPLPLRQRLRPVPKGHVPQLLHRQRPVRSLPDDRCPAED
AHQKLSRETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLSRELTQLSPAAPGTSGICA
STPLTPTPCHPDKQHEVEIPSALAKDKDKERRKRPMSQISGVRKLKHSSSLARAGIPRFG
VRTEHEALLAKELEDTNKWGLDIFKVAEYSGNRPLTVIMYSIFQERDLMKTFRIPVNTFI
TYMLTLEDHYHADVAYHNNLHAADVAQSTHVLLSTPALEAVFTDSELALMYNDASVLENH
HLAVGFKLLQEENCDIFQNLSRKQRQTLRKMVIDMVLATDMSKHMNLLADLKTMVETKKV
TSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTERIMEEFFRQGDREREKGM
EISPMCDKHTASVEKSRVATWADLVHPDAQELLDTLEDNREWYQSMIPRSPSPPAPAPAV
SPATTDKFQFELTLEEEEEEEEEEEGESDTEPEGAESPLDEDNSGSKTPGTDDSEPADTK
RLSPGPGDRGSPVTRPGDVDNRRGLQGTLPEDGGGSGGSVPGLCLDTEGNVTFLSLGT
>A0A2N0WZD6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Psychromonas sp. psych-6C06|TrEMBL
MKSKTVQLKADAQGDLAFLQITDTHLFADRQKDLLGIKTVQSFEAVVAHASKYKQCHAVL
STGDLSQDHSAQSYLDFSKHIKTLQLPCYWLPGNHDMQSVMLPSLLSEGLAQTTVIESDH
WQVVLLDSQVEGVPHGLLSPSQLAFLRKTLTNKPQKNTLICVHHHVLPVGSAWLDQHILK
NADELLSLIKPFSNVKAVLSGHVHQAGDKLQDGVRFITTPSTCVQFKPNSDDFALDSVAP
GYRYLKLSAQGEIETVVERIDKDAFSVDADATGY
>A0A0F6RI87|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter amalonaticus Y19|TrEMBL
MESLLNLSLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHADGQEYDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKCVMIGD
QWQILLLDSQVFGVPHGELSEFQLEWLERKLAEAPERNTLLLLHHHPMPSGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDNIA
PGWRTLELFADGTLNTDVCRLQGTEFRPDTASEGY
>A0A6P6F675|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bombus impatiens|TrEMBL
MASPSNDSFFPNEGLNILDDILLSNGKTEYDVLRRRSSFEDVAVDDDENADCSALKGPQN
IEAHPLTNSVPSLIKILLVFPKDDQQMDVLATTSRRLGWSVSVAKDAEKAVEFFQNRGHE
LVIIDHRGQRAAEADTICRYGELFFKNQSNSSDVRLYILINTIYFRAIRSSPAYHNSIII
ALVKKSFLMHGEKDKIVTLDLLETGFSRALMECSHERLLINELVGIYASALLPRTQLAAA
NALYVALDRCRDMVHVTNDKHIVQFVNKISEKLLGYKTSEILGKSIADIVVYDNFVLMEQ
HISKGREFEGNMNCKRKNNQMITISCRVIPFSINLKKPTHYIYIYDTTYLSENIGSLSPT
PSQSVYSRGNMIVSQRRTSDMKSSEGRRRSSAHKLHSLQLDAPITKVISLLSNAITESTT
PDTAAQIEKAIDILKTTELYVPSLREDTDPVTTDLVGALLASPRKAWESRRSSVESTRVS
TSKAFTTTTASRMQIKSFRGPQEIAEILERCLEWNFDIFKLEILTEKRPLLFLGTTIMNM
YRVPARLGCEEKVVQNWLTVIEMNYQSRNSYHNSTHAADVLQATARFMQSERLQQILEPL
DEVATLVAAAAHDVDHPGRSSQFLCNSDNKLAILYNDLSVLESHHAALTFKLSLSDDNVN
IFKNLERDTYKQLRQTVIDMILATEMTKHFEHLAKFMNICSARMMDSPQLDDYTDTVDMS
VVLQPENVVLVKRMMIKCADVSNPTRPLKCCVEWARRIAEEYFNQTDEEKRMQLPVLMPM
FDRATCSIPKAQIGFVDFIINDMVEAWDAFIDMPEMVGYMRQNYEKWKEYNDRGISTLPD
IEKIQELPELRIYQLPS
>A0A6P8LH85|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bombus impatiens|TrEMBL
MGCKTSMLECIEDTGEAEKRKHSDMVNQGSLLGKTEYDVLRRRSSFEDVAVDDDENADCS
ALKGPQNIEAHPLTNSVPSLIKILLVFPKDDQQMDVLATTSRRLGWSVSVAKDAEKAVEF
FQNRGHELVIIDHRGQRAAEADTICRAIRSSPAYHNSIIIALVKKSFLMHGEKDKIVTLD
LLETGFSRALMECSHERLLINELVGIYASALLPRTQLAAANALYVALDRCRDMVHVTNDK
HIVQFVNKISEKLLGYKTSEILGKSIADIVVYDNFVLMEQHISKGREFEGNMNCKRKNNQ
MITISCRVIPFSINLKKPTHYIYIYDTTYLSENIGSLSPTPSQSVYSRGNMIVSQRRTSD
MKSSEGRRRSSAHKLHSLQLDAPITKVISLLSNAITESTTPDTAAQIEKAIDILKTTELY
VPSLREDTDPVTTDLVGALLASPRKAWESRRSSVESTRVSTSKAFTTTTASRMQIKSFRG
PQEIAEILERCLEWNFDIFKLEILTEKRPLLFLGTTIMNMYRVPARLGCEEKVVQNWLTV
IEMNYQSRNSYHNSTHAADVLQATARFMQSERLQQILEPLDEVATLVAAAAHDVDHPGRS
SQFLCNSDNKLAILYNDLSVLESHHAALTFKLSLSDDNVNIFKNLERDTYKQLRQTVIDM
ILATEMTKHFEHLAKFMNICSARMMDSPQLDDYTDTVDMSVVLQPENVVLVKRMMIKCAD
VSNPTRPLKCCVEWARRIAEEYFNQTDEEKRMQLPVLMPMFDRATCSIPKAQIGFVDFII
NDMVEAWDAFIDMPEMVGYMRQNYEKWKEYNDRGISTLPDIEKIQELPELRIYQLPS
>A0A849V2T4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methyloglobulus sp|TrEMBL
MQEISPYLSILQLTDPHIMESPKATLLGVNTAYYFNAVIAHAMNLARHFDLCLVTGDLAQ
DPCVESYQYLFSQLQPLNIPIRCLPGNHDDFDIMQTVLCTETVNCGKRVVLGNWQILNLN
SQIINSPDGVISTKELAFLEHCLQNHPDLFTLIALHHHCLPTGSRWLDKMIIKNARDLFT
LINRYPKVKAIINGHIHQAMDAQINDVQVLSTPSTCFQFRPESATFSLDDTSPGYRWLNL
YNDGSINSEVVRLPEPLIGLQAHPKGY
>A0A6S7CAY0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter pulmonis|TrEMBL
MARVHTLARRNDAPAMLVQLTDCHLFGEPDTVMLGVNTDASLRAVLRQIEADGKHPDLLL
ATGDLSQDGEPAAYRRLAAMLGAAPALEGARIRCLPGNHDLPAAMRQELPDWSAPVSDVG
AWRVVSLDTTVPGSNAGHLPDSQLDLLEAALAAAPGRHTLLAMHHNPMQIDSHWHDSMMI
DNPQALFKLLTRWPQVRVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNLA
PGYRWIKLYQDGSMATGVRRVQDALWHTATQPDPDSMRAA
>A0A5N3Y388|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas argentinensis|TrEMBL
MAIGHKKASDFCEPVLIYGFTKPASDSIIRTHSRRSTLSRASISPSADSSVLLVQLTDSH
LFADSSGRLLGMDTADSLRRVVEQVLKEQSAIDLILATGDLSQDGSSASYARFVDLSASI
DAPARWIPGNHDDIPTMQAACVGTDLLEPVVDLGSWRITLLDSSIPGAVPGYLQEAQLVL
LERALSEAPDRHHLICLHHHPVDIGCQWMAPIGLRNPEALFAVLERFPQVRAVLWGHVHQ
SIDEQRGSVRLLASPSTCVQFTPGSEDFQADSAAPGYRWLRLHDDGQLETGVSRVDDFVF
TPDYRVGGY
>A0A6A7ZBK1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas helleri|TrEMBL
MPNASTPTTEHSVLLVQLTDSHLFADADGSLLGLNTAQSLQQVVDKARAEQAQVDLLLAT
GDLAQDGSVAAYQRFRQVSEPLCANARWLPGNHDRLAQMREATVQTRLLDPVVDIGNWRI
ILLNSQVPGATPGYLEDEQLQLLARAVSEAPQRHHLVCLHHHPVPVGSEWIAPIGLRNAK
EFWAVLDRFPQVRAVLWGHIHQPFDHVRNGVRLLATPSTCVQFTPGSTDFDVSGEAPGYR
WLRLHPDGALDTGVSRLDNFVFTPDYSANNY
>A0A5E6WPI8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MNRPFLVAQISDLHLKAGQRLTYGVVDTLGALRRAVDHLNASHPRPDIVVISGDLVDFGR
ADEYAVLHPELARLHMPCYLVPGNHDSREPLLDAFRDHHYLPASAQGPLDWVVDEHPLRL
IGLDSTIPGGHGGQLLDSQLQWLDAQLALRPDVPTLLILHHPPFISGIGHMDREPFINAA
ALERVVARHPQVERLLCGHLHRPMQRRFGGSLSCVCPGTSHQIVLDLQEAAPAHFNLEPA
GYLLHRWEAQQGLISHNGVFGDYPGPYPFYDAHGLID
>A0A5H5KEY7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Telelkebir|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>F3KYT1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aequoribacter fuscus|TrEMBL
MTSLLDTIVIEHDPAQAVDVLQITDTHLGVEPNTPLLSMDTDDSLLAVLDSAGKVLPAPD
LLLATGDLSDQGALNAYFRLRDYTRSVCQHQFWLLGNHDHAETLRQATDDNKDLIRNDIR
VGAWQIVMLNSQIPGQVGGRLGPRQLALLEEALQAGADAGLNTLVCLHHQPEPVGSAWID
SQAVVDADEMFAVIEQYPNAKAVLWGHVHQEVDYLRKSVRMLATPSTCIQFARHSDDFKV
DDLPPGFRHLQLLPDGSINTQVYRVTDRSFTVDLGSSGYL
>A0A5W4AZP5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella hadar|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLLDTRFRPDTASEGY
>A0A8E6Y4I1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella pullorum|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A0D6ISA0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas aeruginosa|TrEMBL
MSRHSNTPATDASVLLVQLSDSHLFAEDGARLLGMDTAHSLEKVVERVAREQPRIDLILA
TGDVSQDGSLDSYTRFRRLSAPLDAPLRWFAGNHDEREPMQRATEGSDLLEQVVDVGNWR
VVLLDSSIPGAVPGYLEEDQLELLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGY
RWLRLHDDGRLETGISRVDDVVFEVDYDTAGY
>A0A0T6SQA1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas veronii|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQANEHPYEVILAT
GDLSQDHSPESYQRFASMMAPLGRPIYWLPGNHDDSPLMTEYLHAAGISESKQLVGDHWQ
VILLDTQVRGKPHGMIGDHQLAALDRALRQYPDRHALITLHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRVASEVWRLPVGQFVPDPNATGY
>A0A5F0KCD4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas taiwanensis|TrEMBL
METELPQAPDGSVRLLQITDTHLFASAEGRLLAVPTAASLAAVLEQVQGNDHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
IILLDTQVRGKPHGVLGDHQLAALDSALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRIASQVWRLPLGQFVPDPNATGY
>A0A6P8J8L2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila mauritiana|TrEMBL
MIISSQPNLAGSATTTTTTTITSAHVSQEGSMPLPLPVPVTIPLPIAGTCNCGAVGVGMG
MALGARQCPSPAVDPTTATATPTSTTPGRDSLTRPASESELNVGTGTSGTSSSGGNSRPG
HRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLVFHKSDSICEAITAACQ
RHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSSKNLDAEHIARTIRHTHGHHLT
TIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMSTQQ
ALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSDLSTISEQC
KNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQPK
EAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQENCSADE
ARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGS
STRTAAIVPAKMKSNPIIMELLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFAT
LNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDMLVMDRMEEAT
ALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLGDDKINIFKN
LDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPRDHNPQTDEETSILMRRML
IKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRATCSIPKSQIGF
IEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLAEIMAKQPPVGKMANSK
>A0A6P8JJY9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila mauritiana|TrEMBL
MGCSPSTLPPAPSAGQTGERGSLPLDASEKDESRLFCIKLRRSRLRRCSCGGVTLQPPSD
GNGSTAGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHSVVRRATGSTG
TSGTSSSGGNSRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLVFH
KSDSICEAITAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSSKNLDAEH
IARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQIL
HSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLE
DIFVSDLSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVP
GGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKII
NLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYS
SRRSSNDSIIRTGSSTRTAAIVPAKMKSNPIIMELLDESLSWDFDIFKLEEITDYHPLLY
LGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLT
NKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITF
KLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPRDHNP
QTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMF
DRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLAEI
MAKQPPVGKMANSK
>A0A5I8V0A5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Choleraesuis|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A143I2M3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter asburiae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLTGAKFRPDTASEGY
>A0A1C3ISC6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIEPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDD
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPDRNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAILCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTQVRRLPSGQFSPDFDAGGY
>K5SX90|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio harveyi|TrEMBL
MQPSSDSIKLLQITDTHLFEADEGSLLSVRTADSFAAVVKEILHRQVPFEYILATGDISQ
DHSAESYQRFAEGISPLKKDCFWLPGNHDYKPNMGSVLPSPQIQAVEHLKLGDHWQVILL
DSQVVGVPHGRLSDQQLTLLEEKLAENPQRHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFDNVKGILCGHVHQDMNIIHKGIRVMATPSTCVQFKPNSDDFALDTQSPGWRELE
LHSNGDISTQVNRLPDGQFQPDFTSSGY
>A0A7X5JN90|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter pasteurii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQCVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRIFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVCRLQGNRFHPDTASEGY
>Q7QJ01|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles gambiae|TrEMBL
MWFTGYCCGVKGARTAAVGRNHSHDHNKDDGEDYHQTVMGCTPSILSNGSNNQQQQQSRK
DSGLYVGNVTSSGNGSNDTSNAAAAAAGNNNKLSNSSPVNPTMVNAPYPGAASKDGGTEK
ESAKKDSIVSISATGHITSFPVVSTTVRRPTAGSGTSSSSGRYGHRKSSLALTPEEEPLD
SCPRLVSDLKFPNLLPPNPVIKILIAFCKNDPVFEALVNASHRLSLEPTFVKSAESAIDA
FQNPSSGGHHIIIVDARYPRTIEAEALGRSIRNSKGSQHTTMVAVVKKSVFEKDDTAVIS
LLDVGYNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQALYTALHRSREAVIITDDT
LRAQYANRASERVLNMKLDEIVGRSLSDLVTADISNILSHTSRYKDYDGYLTTRRKSQES
SQIHVRAVPVSCIGRNPTHLVLILESSSSALVSTNAIGEALQTLPQGKEVPRGSLHSIRR
GSFDVRSIASDGLRRTSLAKLSSLPLEAPITKVLSLLAQVQENCSLDEAKLLDRVMEFLK
REGLYSPQMKEIRTEDPVATDLIGALLTQGPTNILSSRRSSNDSIIRGGGRPSTGSIVFN
KTKESSQLSDLLQTALDWDFEIFKLEDLTEKRPLVCLGLELFRRFDVYNTFNCDEMTFKL
WLIEMEKHYHSENTYHNSTHAADVMQATAVYLQQLSNRELKIMDRMDEATALIAAATHDI
DHPGRSSAFLCNSDNTLALLYNDICVLESHHAATTFRLTLGDDKINIFKHLDRDMYKLAR
SIIVDMILATEMTRHFEHLAKFVSVFGTDVESKDPLPPDNDDNQILVRRMLIKCADVSNP
TRPLKFCVEWARRIAEEYFMQTDEEKRKNLPIVMPMFDRTTCSISKSQIGFIEYIIHDMM
DAWNSFIEMPEIIRYMEFNYSQWKLFEEQGINTLSDIKRKQMSLTEDTASSISLEEKF
>A0A8G8S0U2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKHVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPGRHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A379GBL3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteus mirabilis|TrEMBL
MESQLELSVDQQHTVRILQITDTHLFANVDDTLLGINTYRSYHAVLDAIKQQGLSIDLIV
ATGDLVQDQSFAAYQHFADGIARLPSPCVWLPGNHDYQPAMIDALNQAGILSAKQVLIGE
HWQLLLLDSQIQGVPHGELSDCQLDWLTRCLESHKERDTVILLHHHPMPSGCTWLDQHSL
RNSHQLAERVKDHPQIKMMLCGHIHQEMDEMWNGIRLLATPSTCIQFRPHCTNFSLDTVS
PGWRYLELSLSAQGKRNIDTQVHRLVGKDFCPDLDADGY
>A0A7J0B7C1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MQKSFQKATIITINHFEMKLYKLSLTATALAFAVAVNAQSTFKSSLPVKPGKGVTVAGTV
ECDGKPVAGVTVSDGYEVTKTDKKGAYYLKSKKQNPQVFITTPSGYEAVREDVMPQFWAD
FTMPADKYERLDFCLKKTDNKKHAVIFLADIHLANERNDVDIFSGPYVDRIKEEVSKLKA
AGIPAYTINLGDGSWDLYWYAHQYSINDLRGTLNEADYPTAFFNVMGNHDNDGATPAGEG
ADFRASLPYQKTFGPRYYSHNIGDVHYVFLDNIDYINDTLENPSYPGITGRRNYKENFTQ
DQLDWLRKDLAGVSYDTPVVVSMHCPLLRWKKNDGSAYRLKPEETSSRELLSILKPYKNV
HTFSGHSHRQCIVRMPEEEQNLADHNISGACGSWWRTRATALKNLCPDGTPAGYELFTVD
GSDLKWEHKAFEYPEDRQFYAWDMNGVKDYFANNREMRAFLKNYPKWTDYSDVPENYIYV
NLWAWDPEGTLKITENGKELPVEIVTEENPLYTVSYMVRNTIWLNQVENKGYQKPRKFQL
FRAKASTPDAPVEISWTDFFGNETKSTLDRPAPFTLEAL
>A0A090LDV4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Strongyloides ratti|TrEMBL
MRWCCGASCSGTPFTLICGNSTNNQNGVDNTSQNSTTLHDKRKKNFNNPIKTSKRSSSTP
VTVIASSNSVLVGSNRSLENSSSTIKYVNTETKVKDKKFSFTTTSSNSFDYSPTSSLLPK
NSESESNNNKDGKKNSHKRTSNILSSKLLFSGKSNKLPPVQEMPTSVEAFGHMLLKSQKS
ALIISAISSIVNIPFIEALTQSGWNIFYSDSKDLESLSKENAYFTPTVIIIDSKISTFSS
LISSLHTLPYYQDDVFLVALVERSISEKRKQRLVSSVIHHTVVATSTDISLFEFFARLSA
RLRAIPALFAVIEEAEQPIEICDQTNSIQYVNKAYEVLTGLSRSQILGLKGSSMRRRSLN
NLSTTRNNNIFQSSTSSSITQPTTPQPLDSENLAGNVTFSTTGIEVPNINYGDNNINQNN
ISGRRKSCEWHCIPIPLTNTSYNSQYVYVKRGSNDDSIYRDMSSFKSRNSNNGFPESPIN
EVIGLLREALSRCDEDMKPMIREAVKTLSSNELYTPQLSKMKDSDRLNNGYYDGLIRVQP
SLSRQRKRSVVDAFHTNKKISDNNRRRISTDVRNALENETNWDFDIIQLERITDHHALTY
LGMKIFDKWKVHEHLNCSREIIGRWFQVIESHYHNDNSYHNATHAADVLQATSVFLESEV
VAEHVVDTHAIAALIAAAIHDLDHPGRENHHVALTFQITVPDKNINIFQNMNREEYNGLR
QAIVDMVLATDMSRHFEYLTKFQQTLLNLPDEENRESNSLAICRMMIKCADISNPVRQWK
ISQDWAFRIVNEYFEQTKEEIEKGLPVSLLHFNRETCNVPRTQVGFIDMFVREAFTHWCG
FAQIPELLNILEENYEKWKEQIDNWKASDNVKLLSRQI
>A0A5C5HCF8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Give|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5I1NEK1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Cubana|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2I6C5N3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lactobacillus helveticus|TrEMBL
MKLLKYTKGIVDKIIGARKRSAMNKDGELLDPMQKYTTIGEYHVDAEDGTPDGKKFVLTV
YQDKDGVLRQALSSESTTELAPEYVRKYSDELGRFRAFHNKKTGRRYLVEDYLDDYVSEV
KKHIRDGKNSVNLGVITDTHFKDKDSVDFYGWNGLQHVQEFSYLEKFGLLDLKAHLGDWI
DGSDAGLIGESELIKLKDSFKSDKVPYLNIKGNHDENDKFDEHHDPKASFPENEFENIMW
PDMYRQKGIHYVSRQHGVAYFDIDDVRVVSVNTSDVPYILDNKGHKRYDNKITLAVREDQ
IEEIIEILTKSSNKKIVFMSHANPINRKGSNALKYNGRSLHELLVAFNQREKGRMHASEG
EPAEFRLSNYFDFTKVKNARIIAYFCGHRHREDQYRINGIQYILFNCSALMGPNHSLTTK
YNKNLNRKIDHNNEFAGYIVNIDLKRHRIQSFGYGAASRRRVYFI
>A0A1V3IXB3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rodentibacter trehalosifermentans|TrEMBL
MKNTFVYRAEKPIIKLLQITDPHLFKDEKSELLGVNTQSSFSQVLTEIKQENSEFDVILA
TGDLVQDSSDEGYQRFVEMIKPFALPVFWIPGNHDFQPKMVENLNQPPMEKAKHILLGDH
WQILLLDSQVYGVPHGELSRYQLDLLKTTLEAYPQRHTLIVFHHHVLPTNSAWLDQHNLR
NSHELLDVLAPFKNVKAILYGHIHQQVDSQWQGYQVMATPSTCIQFKADSQHFALDDVQP
GWREIELHPDGLIVTEVKRIKQAKFLPNMQEEGY
>A0A0M3UJG8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia marcescens|TrEMBL
MESLFKLPVASGAAVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAIQAQRRDVDLIV
ATGDLAQDHSQEAYRHFAAGIAQLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLLGD
SWQVLMLDSQVFGVPHGELSEYQLEWMERCLQAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAILLRYPKVNTVVCGHIHQDLDLEWQGRRLLATPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A1Y3F6Q8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter seifertii|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIKQILKQHPEADAIIHT
GDLAQAPTPLTYKRYINFMQTLGLPFFHTLGNHDNVDHFPLHNENHQEPVVVGLGNWRII
MLNSAVKGKIDGHLSSEQLKNLANLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFKNVKALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSKDFALDQNAPGYRY
IRLNNDGTFETKVFRLENFKTLINTDISGY
>A0A5U0RS38|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPHVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A5Z3ETE0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRENGVLETEVHRLQDTRFRPDTASEGY
>A0A5Z2CG85|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPCVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A3V0JWB2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella infantis|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A1E5C4N6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterovibrio norvegicus FF-454|TrEMBL
MIRIFKTLRICHLTSQNSQTVRLLQITDTHLFADPYGCLLGVNTAASYKAVVAEIRSQNI
EFDAIIATGDLSQDHTEQSYLRFVEGIADWSQPCYWLPGNHDYQPEMQKALTQSTLVRCD
QVLVGEDWQLVMLDSQVKGVPHGRLSTEQLILLEQALAVNPSRHTLVLLHHHPLPAGSAW
LDQHQLHNQNDFWALVEKYNNVKGVVCGHIHQDLDTQFKGCRVMAAPSTCIQFLPDSDDF
ALDSTNPGWREISLHQDGTITSKIGRLKGSDFQPDMNSSGY
>A0A0Q3TPA2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Amazona aestiva|TrEMBL
MRVTRSVCSVRSFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDY
DLSPKTMSRNSSLPSEQHGDDLIVTPXAQVLASLRSVRNNFTLLTNLHGTSNRKKEDAVL
CICRNDGKYER
>A0A6B3P214|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas brassicae|TrEMBL
MPHSIPSRDASVLLVQLSDSHLFAEADATLLGMNTRDSLRRVVERVREEQPVVDLVLATG
DLSQDGSVESYRWFSKLSGQIEAPARWLAGNHDEPLPMEQAAAGSDVLDPVVDIGHWRVI
MLNSAVPGSVPGLLAEDQLQLLERALREAPERHHLICFHHQPVSIECAWMAPIGLRNADA
LFDLLQGYPQVRALLWGHIHQEWDQWRDGVRLLASPSTCIQFEPRSDDFKVGDQAPGYRW
LRLHDDGRLDTSVSRVTDFAFTVDYGSNGY
>A0A8J6SCI5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trichocoleus sp. FACHB-69|TrEMBL
MIPAKPLAIAQITDIHLFADTKKELLGLPTEKSFHAVLEQLQKLLSQLDILLLTGDLSQD
GKAESYQRLAELLSPLSIPTYWVPGNHDQPLVMQQVLKEAPISPEKSFAAGDWQFLLLDS
HVSGCVHGKLSPESLVWLDTQLKLASDRPILIGFHHPPFLVDSDWLDGSTLQNPEELFAV
IDRHPQVKLVIFGHIHQEFYQRRGGVHYLGSPSTSIQFEPHSHNFSLDKVEPGFRLLNLY
PDGSFETRVQRVTYVHELDLAATGY
>A0A3B5MPQ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xiphophorus couchianus|TrEMBL
ETILLCCSNNSALHINKTRSGNLVSSCKTENGVSPAHTPLGSQSPSRTLNTSLPQGQRRE
SFLYRSDSDYDMSPKAVSRNSSLASEGHAAEDFIVTPFAQVLASLRSVRSNFTLLANVST
PIVK
>K8AQ73|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cronobacter dublinensis 1210|TrEMBL
MESLLNLPVAGGASVRILQITDTHLFAGKNDTLLGINTWESYQAVLAALHAGQREYDLIV
ATGDLAQDHTPEAYAHFAAGVSTLPAPCVWLPGNHDFQPAMFSTLQDAGISPAKRVFAGD
HWQVLLLDSQVFGVPHGELSDYQLEWLERMLQQAPERHTLLLLHHHPLPSGCGWLDQHSL
RNAQSLDDVLNRYPRVKHLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCAGFTLDTVA
PGWRWLNLHPDGSLTTEVCRLEGVQFRPDTASEGY
>A0A345DD95|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ephemeroptericola cinctiostellae|TrEMBL
MSAFIVPVIVLLIASAFYIHHRLVPPTWPRWRRWAAFMVILGLALCLPAQFYLRFAMRET
GIHNTITVVNYGFGFYSLLLTFTLAQGLFGHAVGFTPQHKKLPNDRRQFLRQTSRIGVLG
ATAAVFGYAAERALAEPTVQRIRLPITDLPAELEGLTIAQISDVHIGQLQGEEAYIQKII
ATVNALNVDIMTVTGDVVDGSVARLAHSVEPLRNLRSKYGTYFVTGNHEYYSGAPAWIDH
FKNFGWRILENEHDVLTIANHAVVVAGVHDLKAEQHIIAHSCNPSKALSDAPTDAAFTLL
LAHHPGTAELTNNLNIDLQLSGHTHAGQYFPATWVIQYFHKFARGLNKNNAGWVYVNSGT
GYWGPALRTTDISGEITLMTLARA
>A0A1Q9N9U3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Heimdallarchaeota archaeon (strain LC_2)|TrEMBL
MKFVVFSDAHIGGKFNEETFIEGVKYINEIDADYYIFTGDLTDQGTVFEYELA
>A0A369Z436|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus parainfluenzae|TrEMBL
MSNTFECEPASEIVKLLQITDPHLFKDTSKDLLGINTHESFSQVLKEIQAESFAYDVVLA
TGDLVQDSSDEGYLRFVEMVKPLNKSVFWLPGNHDFQPKMVEHLSQPPINASKHLLLGKH
WQVILLDSQVSGVPHGELSAYQLDWLKMKLAENPARHSLVVLHHHLLPTNSAWLDQHNLR
NAHEFSEVLAQFNNVKGILYGHIHQEVDGYWQGYQTMATPATCIQFKPDSNHFALDTLQP
GWREIELYPDGRIETRVKRIKQKTFLPNMEEEGY
>A0A653PFC8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Frigoribacterium sp. 9N|TrEMBL
MDLRTAEHPRPNHFILHLSDTHLVGGDRDLYGAVDSEARLRQIMDEIEASDGRPEAIVFT
GDLADKGEPEAYRKLRALIEPVAERLGAQVIWAMGNHDDRSAFRSELFGQLPSQRPVDLV
YDVNGLRVITLDTTVPGHHFGRLSGDQLDWLAEELSTDAPDGTIIAMHHPPVPSVQDLTA
LVELRDQAALAEVIEGSDVRSIIAGHLHYSTNATFAGVPVSVASATCYTQDLNVAGGGTR
GRDGAQAFNLVHVYEGTVVHSVVPIGTYETVGEYVPADVVAERLAVAGVRIAPAAPRHRA
TDTAPVPVVPRDLALTGPIDTL
>A0A212INF7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured Citrobacter sp|TrEMBL
MESLLNLSLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEGQEYDLIV
ATGDLAQDQTAAAYQHFAEGIASFRVPCVWLPGNHDFQPAMYSALQEAGISPAKCVMVGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLAAAPERHTLLLLHHHPMPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDSIG
PGWRTLELFADGTLKTDVCRLQGTEFRPDTASEGY
>A0A446CGJ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter agilis|TrEMBL
MSLRQSSFFLRFLTLGALAHVYVGARLIPDAMLGGEGTAAAILALVLSCVLIPLGMLGRS
SVHPPWGDRIAWVGLFAMGLFSSLFVLTVLRDALLLAAWLATLPVDAALPWPLLRQASAW
TVAALALAGTLVGLYNARRRARVIDVDVPIAGLPADLDGFTIVQISDIHVGPTIKKRYVQ
AIVDAVNEQLPDMIAITGDVVDGSVEHLAAQAGPLGELRAPYGVYLVTGNHEYYSGATPW
VAEFRRLGLRVLMNEHAVIHPAGLPVVVAGVTDYSAGSFDPQQRSNPLAALSGAPADALP
KILLAHQPRSAAAAEPLGYTLQLSGHTHGGQFFPWGFFVRFQQPYTAGLHRMGNMWVYTS
RGTGYWGPPKRLGAPSEITRLRLRAAPAR
>W1HNV9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pneumoniae IS39|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A2Z2P7Z5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Granulosicoccus antarcticus IMCC3135|TrEMBL
MPPCELPGVAVIADAHFHAIDSDYDLPATVFNGQSATLRSWIDTRRSSRVFNESGAALKA
ALKDIADRGIRHIVLLGDYTDDGQLEATQRLVQLLQLYQDRYSMQFYAIPGNHDCYGPVG
KHQSTRFTSTPGNTVLVTSDPEVAASESDTSVLTRKMYCDGAPAGLLPMREFGLCRQDGY
LHWESPFGLDDSFASRRYEAHSADGGTVRSLIDASYLVEPEPGLWLLMIDANVFEPRNGQ
REITRKKAFFDSSDAGWNAVLRCKPHLITWISDVSKRARQLGKALLSFSHYPAMDAFDDW
SLSESRLFGQTETLRRRPDKQVAETLLEVGLRLHLGGHLHINGKSTCNIGNQQFTDIAVP
SLAAFPPAYKSLHATAERCRVETISLNSLALDPWLLGCYRAENDALKRSQDRALDALNYG
DFLYKRMYSRVAQSYLPKEWPTDIAGELEGRNVADLASFLIAQRRGARRNGARQLGAQHD
GIPAIDTQYAAELKSLSIAHSLDIDVFQDCSIMDLIVDWYCLRHAGHQAASFSPLQRLNL
YRFLAQEFGDLQSVENNPTAAFFHVFLGVLQQSLQRLEPAGSMTDFIELRP
>A0A808IIA9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. Crenshaw|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLTGAKFRPDTASEGY
>A0A085J9E1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Tatumella ptyseos ATCC 33301|TrEMBL
MLQLTDTHLFQGRHESLLGVNTWAGFQAVLDAILEQQDHFDLIIATGDLAQDHSVQAYRN
FAEGISRLPAPCVWLPGNHDFQPAMYDTLASAGISQCRHVLLGDDWQMLLLDSQVYGVPH
GMLCDFQLEWLETTLSRSPERDTIILLHHHPVPSGCRWLDQHSLRNSHQLDAVLQGYPRV
RALICGHIHQEMDEDWQGRRVLSSPSTCVQFKPHCSGFTIDALPPGWRWLTLKPGGEIET
AVCRLNTTDFLPDLESEGY
>A0A5J4PZH1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MGRTLFIVSAVIVISSFFLSVLIGNHLPSSVTSIMYRVGTSWFFIFVYLLILFLLLDLLR
LTHLLPIHRFMYGSWIGFGILAGFLTVVMSLGYFNYIRKEKVELSLEINKDAAVSSLKIA
AISDLHLGYGIHRKEFEQWVQLINKENPDIVLIAGDVIDNHPRLLYEQN
>A0A5J4SPK9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MKLFPIISALLLILGANFYVFYRLWAMLPTGVGRVLLVVFGIVALSSFVLVQVVGNNLPL
PLAALMYRVGTTWFFIFIYLLIIFLLLELIRVTGLLPVARFMYESWYGFGVLAGALTLIL
TGGYIVYLHKARVELSLTVNKEVGAERSLKIVAISDLHLGYGIGRKEFEGWVELINKEHP
DIVLIAGDAIDNSVRPLYERGIAESFRQINANYGVYASPGNHEYITGISNSLAFLKEAGV
TVLRDSVAFINNTFYIAGRDDRSNSARKSVEELTDTLDKSKLLILLDHQPYHLEQAEKNG
VDLQISGHTHHGQIVPISWITEMIYEKAHGYLKKGDSHIYVSSGLGLWGGKFRIGTRSEY
VVIHLTPK
>A0A7Y8PAV0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. Swhac1|TrEMBL
MTLFSNNHQQRWTIVQISDTHLMNQEDLEFVHMNPERSFHSVMHDIQQQYPQLDAIFHTG
DLAQIPVTETYQRYLQFMQSLNTPHFQIPGNHDDAAVFPFHLQSNQVHAIELGNWSVILL
NTAVKGRIDGWMDTAQLQQLDQVLQQHAQQQVIIACHHHPFDMQSHWIDQHKLKNTEALI
DVLARHNNVKLVLCGHVHQDSLNEWQGIQFYSTPSTCVQFKPHSQHFALGPEAPGYRVLH
LNADGSFSTQVHRVEHVTQQINFEISGY
>A0A856PX64|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Peptacetobacter hiranonis|TrEMBL
MKIKKLKVIIASILLVALLLVWGTNDIVTSEYFISSEKIPADFDGYRIVQISDLHNKEFG
KNQKRLIKKIKAANPDLIVITGDIVDRRKWGTKYMEKFLAESKGIAPMYYVSGNHEVWSF
KYDKVKKILEKYGVNILDDDVKTIKHKNSEIKIAGIIDTGFEDREEYVPEILKTLKNKIK
SNEYSILLSHRPEHIDDYADAGYDLVFSGHAHGGQIRIPFIGGIYAPHQGIMPKYTKGVI
NKRKTKMVVSRGLGNSVIPIRVLNRPEITVTVLKSNQ
>Q7VN37|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus ducreyi (strain 35000HP / ATCC 700724)|TrEMBL
MGNFYSLGKKEPVIRLLQITDCHLFSSESECLLGINTTETFQAVIEHIHQTDFAYDAVLA
TGDLIQDHNPEAYHRFAEMAKQFVKPLFWLEGNHDKQPQMSLYLGKHPHIQPEKQLLAGE
KWQILLLNSQVAGAPSGYLSAGQLAWLNSKLAKHLDRYALVVLHHNILPTNSAWLDQHCL
KNSEQLAKVLKSYRNVKAILHGHIHQEVDRVWQGYRVLATPSTCIQFKPNCRDFTLDMLP
QGWREISLLEDGSIETTVKRLASNQFLPDFQSKGY
>A0A735PV96|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae serovar 42:z:1,5|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGD
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A6I2ID38|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacteriaceae bacterium RIT714|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIRTENRDCDLIV
ATGDLAQDQSAAAYQHFATGIASFSVPCVWLPGNHDFQPAMFSVLQDAGISPAKRVFVGE
HWQILLLDTQVFGVPHGELSDFQLEWLETKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLMKYPNVNNLLCGHIHQEQDLEWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLHADGTLTTEVCRLEGAEFRPDTASEGY
>A0A2S6QJX5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alphaproteobacteria bacterium MarineAlpha12_Bin1|TrEMBL
MEQNLRLAHFSDVHLDKDTESADFTRNAFDNLLKEVLFHNPSLLLIAGDLFDSNDASDYT
IEWVMEKLSNLTIPVAMIPGNHDSLEQGSVYYRYDFNLIPNVDFLSQEDGGLIYITSIGV
SVWGKGIKKHDRKFRPLKNCPPRPKYSKWYIGLGHGLFIDDETQAHRASPILMEDLDNCD
CDYLALGHHHAALHLQNVATTAVYSGSPTDDVGRGPTYVVADLKQYKKPDVKIFTL
>A0A1V3L9P3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rodentibacter ratti|TrEMBL
MKNTFVYRTEKPIVKLLQITDPHLFKDEENELLGVNTQASFAQVLKEIQQENTEFDAILA
TGDLVQDSSDEGYQRFVNMVKPFELPVFWIPGNHDFQPKMVENLNQPPMEKAKHILLGKY
WQVLLLDSQVYGVPHGELSQYQLDLLRTTLEQYPERHTLIVFHHHVLPTNSAWLDQHNLR
NSHDLFDVLSAFKNVKGILYGHIHQQVDSFWQGYQVMATPSTCIQFKSDSQHFALDKVQP
GWREIELHSDGSIVTMVKRIRQAVFLPNMQEEGY
>A0A4V1BQB2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter tructae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPDYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIS
PGWRTLELFADGTLHTQVCRLPGNRFHPDTASEGY
>A0A329HGN1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. RIT 411|TrEMBL
MSLPDSVNAPLVIQLTDSHLFARANGRLLGIDTAASLQQVVAQVVREQPRIDLLLASGDL
SQDGSVASYQRFCELTEPLAAPMRWLAGNHDENAPMAKACGDRDFLETVTDLGAWRLILL
DSTVRGCVFGELEQAQLVALDEALSAAPERPALICLHHHPVPVGCGWMEPLGLHRADELF
AVLDRHPQVKVVLWGHIHQEFDQLRNGVRLLASPSTGLQFEPGSEDFKAGDQAPGYRWLR
LLPDGNLETGVSRLQQHAFTVDHSAAGY
>A0A661GKA4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MVPQQDIIPGPPLRLVQLTDLHLLGDPAARLRGVDTGATWRAVFGAAREDLARADLLLLT
GDLAEHGEAVAYARLSDDLESVERGVRVRAIPGNHDDPARLAEAFHATGEARVMALSHGG
WQVLLLDSSIPGQSAGHLDSNQLDWLDTRLAKAPERHVLVVLHHPPLPITSPWLDAIALD
NGAELNARLDRHANVRGVLFGHVHQAFEKRRRGVRYLATPSTCVQFVPGTEQPEVDTLTP
GWRTLALHPDGRIQTRIRRLPVSLPQELATKRRRSR
>A0A2J8V5P3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pongo abelii|TrEMBL
MAQQTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKPKTARKSVSPKLSPVTSP
RNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVH
SQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALT
NLQDRAPSKRSPMCNQPSINKATITGLYNGIIAFL
>A0A8I5T5U0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pongo abelii|TrEMBL
MAQQTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKPKTARKSVSPKLSPVTSP
RNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVH
SQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALT
NLQDRAPSKRSPMCNQPSINKATITGSMELNPYTLLDM
>A0A523MI58|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MTTVISATSSFRLLHLTDPHLHAHADARMRGINTFDTFRAVIKCAMSNPTPPDAILATGD
LVQDETRAGYERFRDELKPYGLPVYCIPGNHDAPDLMAKILNEPPFKVGGVIEQGAWALV
LLDTHCPGDDGGRLCASELQRLEDALDGYRAKHVLIALHHHPIRMGSRWLDGVALRNADD
FLDIVDRHPQVRGIIWGHVHQASDRRRNDVRLMSTPSTCLQFLPNSDDFAVDSRTPGFRW
LNLRNNGAIETEVFWLE
>A0A2J8T633|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pongo abelii|TrEMBL
MQGPPAPAPVPGPGSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENGLSCGR
RALDPQSSPGLGRVMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIV
TPFAQVLASLRTVRSNVAALARLQCLGAAKGHGAEAGIGDARRAGLVPGSVGDAADPALG
GGDGLQQVQADPEPGVDPPVRNQPLWEPGVPVHLPDLPGPAD
>A0A142G1D9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aggregatibacter actinomycetemcomitans|TrEMBL
MLNTYKYDTRQEVFRVIQITDPHLFKDATGELLGVNTQESFSQVLSEIRQQLYDYDLVLA
TGDLVQDSSEEGYLRFCESVKPLKKTVFWIPGNHDFQPKMFDILKRDNICDKKHILLGEN
WQILLLDSQIAGVPHGQLGQYQLDWLMAKLKEHPQRYSLVVLHHHILSTHSAWLDQHNLR
NAHELAYTLAPFNNVKGILYGHIHQQVDGEWNGYKIMATPSTGIQFKPDSNTFALDTAQP
GWREIELYADGRIETRVKRIQHKTFLPNLQEEGY
>A0A564FW01|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium dankookense|TrEMBL
MTTVWVMSDLHIDASPWTPPPGPRVDVAIVAGDVADGLCRRALPWLAEHVVPRARHVIYV
PGNHDLWRTRLPDELARARDAAIAADVTLLDCGQARHVDGVQVIGATLWTDYAVGGADHR
ALAMRVAGDRQTGMRDHRLIQTRDRLGTPAAFRPPAAAALHAEHRARIERCLAEPWDGPR
IVVTHHAPHPRSLLHGEVREPIDAAYASDLTAILEGEHAPDLWIHGHVHRTVDYRLGRTR
VLANARGHDTSHRRRNGEWRVELENSAFDPFLTLEI
>A0A564G670|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium dankookense|TrEMBL
MTARLWVLSDLHLDVCPLDLDPPPHDVAVIAGDVGERLCDRVLPWLRVLRGPAVYVPGNH
DWWRTTYQREVAEARELAAAAGITLLIEGEVATVAGVRFVGATLWTDWSLRLDQQARAMS
DGAGRAGGMRDVRKIKWRRGPGDYSAFLPRVSGGLHREQRRRIEAALAEPYAGPTVVVTH
HAPHERSLRGGGWQTPLDAAYASDLSAILEGPTAPALWIHGHIHECRDYVVGGTRVVANP
RGYITESPGSRLRAPSREVENPAWDPALIVEV
>A0A2H5ZKY7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR30|TrEMBL
MAKFALISDPHITVPNPETGWMLREPVPNEPTMYAHSVELLEQAIAEINAIPEIDFVVCA
GDLTKDSEPYNHDCVRELLSRFRAPVFCVPGNHDQPRPPQLRPPELLDPSVRPLRTEELP
WLYRDFGFQQGDILAFSCDPTPDVHLVGLCSAKPNDDRGYIPPQTLAWLEHDLSHQRDPE
RHTIVLLHHSIVEHVPNERIDPTFSWFHVENSDALKSVLQRHRVKITLSGHLHIQDIKQE
AGLYNIVTASLAGYPHAYRVFSLEGNELHVESRRLESIPSIPNLQEYSRAYTSETFVQII
AQSLQKPPFELSETQALETAKRLRDWWPTIAEGDERFSYAAEELGSAALAAYVNSFTDSD
PPDNDCVLVL
>A0A2H6B8C8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR41|TrEMBL
MTVIAQISDLHVGGARHEPALLDQVLVEIAELAPDLVVVCGDLTDEGYPDQYEVVKAALA
RLDGLEVVAVPGNHDAKHVGYLHWEAMLGERETTRRLTIDGEAVTIVGVDSSKPDIDEGE
VGREHYKPIQEALAAPADLRVFVCHHHLLPIPGTGRERNQVADAGDVLALLGANGVDLVL
GGHRHVPFAWRIGGLVVAHSGTAASLRTRAFPHPAYNVITVGPESIAVELRVPGGERQAL
ATFPRQRPTQANGCVTPGLPRQGFEWLVDPVRASGRALRSS
>A0A090NHV6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella dysenteriae WRSd3|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A6J5FID6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia caffeinilytica|TrEMBL
MKIRVLSDLHLEYDEPELIPHAHADLIVLAGDIHNHAAGPRWAAQTFDGAVPVIYVPGNH
EYYDGEFGALETALYDAAAQVDNVHVLNNAALIDPQGRWRVLGATLWTDFALYGADPDTL
TESIDASRRVMLDFRGLIQMNWPHDTQDSPRDFTPDDSLALHRRARAWLESELAKPFGGK
TIVVTHHAPHRQSLAERYAEDRASAGFVNHLPDLVRSPVALWIHGHTHTSFDYTVNGTRV
VCNPRGYLDRRTRQPENPQFTWDKVVEI
>A0A3S1BGG5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. PAMC 29040|TrEMBL
MPSVSTLTTEDPVLLVQLTDSHLFADAEGSLLGLRTADSLQQVIDLVRGEQPQVDLLLGT
GDLAQDGSIAAYQRFRQLTGSLCAKARWIPGNHDNLPHMREAAVQSRLLDPVVDLGNWRI
TLLHSNVEQKSQGYLQDSQLQLLAQSLSEAPDRHHLICLHHHPVPVGCEWIEPIGLCNAG
EFWKVIDRYPQVRGVLWGHVHQAFDQQRNGVRLLASPSTCIQFAPGSADFKVSSEAPGYR
WLRLQPDGTLQTGVSRVTDFVFEPDYSANNY
>A0A8C8GR91|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oncorhynchus tshawytscha|TrEMBL
KCHTKHHFKRMLNRELTQLSETSRSGNQVSEFIANTFLEKQQDVEIMSGPLKDKDKKKRP
MSQIVAVKKPALSPSLAPTQIPRFGVTTLHEGLLATEFEDINRWGLDIFKIAEYSGNRPL
TVVMYSIFQERELLKNFKIPADTFVTFMMTLEDHYHTDVAYHNNIHAADVVQSTHILLST
PALEAVFTDLEIMAALFSSAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGF
KLLQEDNCDIFQSLSKKQGQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVL
LLDNYSDRIQVLQNMVHCADLSNPTKPLDVYRQWTDRIMMEFFTQGDRERDKGMEISPMC
DKHNASVEKTQVLYCTAHVHSIQVVCTQAKARRLSHSRKSANPPADL
>A0A2N7NK24|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio tasmaniensis|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDAIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLDKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGNN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWEVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGSVSTQVRRLPHGQFLPDFEAAGY
>I3D8Z9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus parahaemolyticus HK385|TrEMBL
MNTFYPLEPKTSVIKLLQITDPHLFSDTTKDLLGVNTHASFQAVLDEIQAEIQTQAVDFD
AILATGDLIQDHQSEGYLHFAEMIRPLAKPVFWLEGNHDQQPQMSLLLGKFDYIRPEKQI
FAGKHWQILMLNSQVASAPSGFLSKGQLAWLNQKLSENPERFTLVVLHHNILFTHSAWLD
QHSLKNSDTLAEILALYPNVKAILHGHIHQEVDAIWNGIRILSTPSTCIQFKPNCDDFTL
DNLPQGWRELSLFEDGRIETEVKRLKTQAFLPNFDSQGY
>I3D7R7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurella bettyae CCUG 2042|TrEMBL
MINTHIYDTDADVVRLVQVTDPHLFKDEKGELLGINTQASFAQVLHEIKASSYEYELVLA
TGDIVQDSSEEAYLRFCQSIQQLDKMVFWLPGNHDFQPKMFSILNQENGNISPKKHILVG
KKWQIVMLDSQVFGVPHGELTPYQLDWLDTKLKEYPDRYALIVLHHHILPTHSAWLDQHN
LRNAHELLNILSHYDYVKGIVYGHIHQAVNGLWHGYKVMATPSTCIQFKPDSNVFSLDLL
QPGWREIELHTDGTIHTQVHRIKQATFLPNMHEEGY
>A0A850GV83|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter lutaoensis|TrEMBL
MTRPDKAPSLRVLQITDPHLMARAEGALLGVNTRDSLSAVIGEARRHHGQPDLILATGDL
AQDGSEAAYRVFGDSLACFGSDMAWLAGNHDDTATLARTATHYGADRRQLVRGGWNIVLL
DSSVAGQVHGELVARELTFLDTALAAEPQRPALVALHHHPVDIGSGWMDRIGLRNREAFW
AVIDRHPQVRVVLWGHVHQAFDGERNGVRLLATPSTCIQFARGSREFAVEPLAPGYRWLE
LAPDGGLVTEVRRADGFRFELDQNSSGY
>A0A5E8ALR7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Roseovarius sp. EC-HK134|TrEMBL
MHKILVFTDVHIVAQGQTIIGLDPFARFTQGLAHALTRHPDAARIVLCGDLTHRAAPEEY
ARLREALADCPLPVSLMLGNHDRRAAFLTAFPETTQMDSGHIQHTADIGAYRLICLDTLD
EAAPDLHSGWLCPARLDWLDQRLNEAGPRPVIVFTHHPPIDTGFAGMDAIGLRNRDELIA
RLSAADNVVQIMSGHIHRTVQGSAGGIPTAILKSPCHQMPMSLDAQDTSLSIDEPGAYGL
LLLTETGVIVHTEDFTLPATLSATYS
>A0A2G4WK23|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium leiognathi|TrEMBL
MQTYLLPQTNPESVVLLQITDTHLFANESGSLLGVATQKSFHAVLDAVDTVAREFDAIVA
TGDISQDHTPESYQEFAGGIARWSQPCFWLPGNHDYQPTMASVLPSEQIKPCEQVLVGEH
WQMILLDSQVAGVPHGQLSQAQLALLDSALSQYPERHALVLLHHHPLPAGSAWLDQHQLH
NNDALWEVVEKHPQVKAILCGHIHQELDRMYRGVRVLATPSTCIQFLPDSDDFALDQENP
GWRYLELTPKGDVITHVHRLEGDQFKPTFDAAGY
>B4P9Q8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila yakuba|TrEMBL
MGCSPSTLPPAPSAAGQTGERGSLPLDASEKDESRLFCIKLRRSRLRRCSCGGVTLQPPS
DGNGSTAGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHSVVRRATGST
GTSGTSSSGGNSRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLVF
HKSDSICEAITAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSSKNLDAE
HIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQI
LHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQL
EDIFVSDLSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDV
PGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKI
INLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVY
SSRRSSNDSIIRTGSSTRTAAIVPAKMKSNPIIMELLDESLSWDFDIFKLEEITDYHPLL
YLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQL
TNKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAIT
FKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPRDHN
PQTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPM
FDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLAE
IMAKQPPVGKMANSKXHTAFRRLFSGLLKPLPAHAPGTSTIGENEMEDVL
>A0A2J7VAK3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Variovorax sp. B4|TrEMBL
MSCLLHMSDPHFGTEQPEVMRALAMLVQTERPSALVLSGDITQRATRAQFARARAFVDSL
AIPRLLAIPGNHDIPLFALSTRLLAPYSRYSAAFGDDLEPVVDVPDFLVVGVNTTRWYRH
ENGATSAQQAERAARRLAKGSARQLRVVVVHQPVAVTREEDHKNLLIGRREAIRIWAEAE
ADLVLGGHIHLPFVLPLHEGAGATARRMWCVQAGTAVSTRLRAGAPNSVNLIRFEGGDGE
RRCTVEQWDCGVGVAQFRRAHVHSLALGNARPRAH
>A0A2H5ZRR3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR31|TrEMBL
MRIYATADLHGRPDRIQAVREAVGRLRPDVLILAGDLTHSGRGREALELLELPDVVVLAI
PGNMDPFDVDEAIVRSPARSPQRACVEHGGVRFGGLGDEPCDVLVVHEPPRGVLDRAWSG
AHIGSVAVRDYVERHRPRVVVCGHVHESPGVERLGDTLVVNCTMGNDRYLGALITWQAPE
PRVELLPRPG
>A0A2W1JT03|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acaryochloris thomasi RCC1774|TrEMBL
MSPSSPLLVAQLSDLHLFSTPEQTLLGLQTMASFAAILDALRQLPQQPDVILLTGDLAQD
ESSAAYEQIAQRIAPLNIPTYWLPGNHDHSPSMASILNQPPIYLDKAFQMGGWQFLMLDS
TVAQQVHGKFSAQHLEQLEQQLQANTNPTLIALHHPPVTIDSAWLDNLGLQNSEAFFAVV
ERYPHVKLAIFGHIHQQVEQHRRGIAYLSTPSTCVQFAPHQKTFALDETRPGFRLLQLYP
DGTFESEVQRVQIDLPQLDVAAQGY
>A0A2W1JFV7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acaryochloris thomasi RCC1774|TrEMBL
MPLNRRKFLLLGGTTIGLATSAAVRGLDRKSASQANHNLSSAPQTSPSPAPQGVFAPQRG
DVRLIVISDMNSQYGSTTYRAEVEAAVKMLPDWQPDLVICAGDMVAGQSLKLSQQQVQSM
WDAFGQKILQPIRKTGLPFALTLGNHDASSYRNPNGKYVYALDREVANSYWSHQEPGLQY
VDRADFPFYYSFQQNEIFYLVWDASSANISDEERVWAERSLASDVAQQAKMRIVIGHLPF
YAVAQGRDRAGEILNRADELRLLLERHNVHTYICGHHHVYFPGRAGELEMLHTGALGSGP
RSWLGSNTAPIQTLTVVDITLDTQTTSYTTYDMGSLEIVKTEQIPRLLVGPNGRELRRDL
TLADLTPEESNQQHVLSK
>A0A7U9QT94|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lachnospiraceae bacterium|TrEMBL
MKLEKPTKYKNTHTLAVLLTLSTFLAAVFISGCASSPHALQENKGQTETAQQPNADTGQN
KTENADTRHQESIEITPEAIDTCQITIPGISREYDLLFFTDTHIIIPETSKEISQEIRDY
SSQRLSEFAGESQFASSDLFQALLSYANDTKPDAVLLGGDIIDSPSPSNMDFLGNSLEKL
EIPYIYTLGNHDWTYPWEYMTETAVNDYLPPLSPYMDGNTSIHTLELDDFIIAAVDNSSN
QINPDALETYKTILTLDKPVLLLVHVPFYTPSLLEEASGFWQQSVVLGGGVHGGTYPNEI
SAEFMGLTTAASSPVAAVIAGHVHFPHVSDMEGEKGIPQIVGDAGFKGRATRIHISP
>A0A1W6VGY2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio alginolyticus|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDAIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLDKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGNN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWEVVQQHINVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGSVSTQVRRLPHGQFLPDFEAAGY
>A0A8C8S541|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pelusios castaneus|TrEMBL
MELTDHKSFSHPIPLSYSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYR
SDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPNKR
SPMCNQPSINKATITGKKD
>A0A345H789|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kordia sp. SMS9|TrEMBL
MNIVTKDIHFGNEVLTLTNQRVLFWEAQEALILSDIHIGKTAHFRQHGIAVPDAILMNDL
QRLQVLIENFNPKKLIVVGDLFHAEYNQNFDVFIQWMQQFDDLEKILIRGNHDRFPTRFY
ESLGFLTKKQAEYNALVFVHDTVKVSAAKYYISGHIHPGVRIKMKGRQYLKLPCFQVNSQ
QLILPAFSLFTGLNTRSTLENIVNYAFTEDAILEL
>A0A7W2JQV2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas mosselii|TrEMBL
MPQPHPLSSPVHVVQLTDAHLFADPAGTLLGLNTRASLGHVIDQVRREQPRIDLLLCTGD
LSQDASAASYQAFSELTSKLEAPARWLPGNHDEAQVMQAVAPELVQAVTDIGQWRIVMLD
SAVVGATFGVLADDQLAVLDQALNSAGERHCLVCCHHQPVDIGCAWIAPIGLRNADELLQ
RLRGYPQVRALLWGHIHQEWDEVRDGVRFLATPSTCIQFAPRSEEFKVSEEQPGYRWLRL
HADGRLETGVERARDFEVKLDFDSPGY
>A0A498DHQ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mariprofundus sp. EBB-1|TrEMBL
MPVSHLLHLTDSHLFSDISRQLKGVNTYDSFSTVIKDAFASTPNPDAIILGGDMAQDEAS
ETYQLLADMLKGWSAPWMISPGNHANVTALERTLIPALESISSYSRCLQFDAWQVVTLNS
HNSGNVSGLLVEDELKRLDSLLAAEPHKHTLIALHHHPAPIECAWLDRIGLHNSQALWQI
IHQHHNVRGLLCGHIHQALDMMHKGIRILGTPSTCVQFKPLQDSFTMDNRSPGYRTITLM
PDGNIQSLVKRIDGFIPKDLNNDEPY
>A0A6P6Y524|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dermatophagoides pteronyssinus|TrEMBL
MEHLSPTNQTISNVNTLKVTKNMSKNNRRSHDHMDDADTSSKIDANILTSQITTIQCKLC
NKEKSDYSTKITTIDNTEQAQQQQQQMMKKRIKRSSQIDDSNQQQNIDDNQHHQDDNDEQ
QQQNHYCCRHQKRIPSNRANIFQNHQPYCCLYGSASSFDRATSVTIARLEPFRDQPSSNL
LEQQCSDSDQVLSAKQNLIDSSSKQDIPDFINNESSSLANQMINNKMNNNNNNKQLTIAT
KMFDQSFIQFGRMNIEMKNPKLLLVFNDKYNNHAKWLFEAGNLAGFSCIDLVDTKESAMN
LYQEKQHELIIIDSRSHENSNSHQQIEHHHHDHHYQQQPHQRHVRFDSQNSARTKFLLQD
SSSSSSSSFSGNTKQPIFDPLNLCRSIRDIKGNEFTIVIALMNKNFYYNDQQQQLIDIYK
SGFNRCIPETFSQDCGYYHYELIQLRQFELQLQMKLRAAQTMMMAIDSCKEGVVITGPSH
DIRYVNHSIEKMFGFRADDMIGQKTQDFFQNDLIKMEVDEKINNYNDGKEWEGQIYHRRK
SGESIPIWNRIMPINYRKGVPEYIIYIKEFPFLFVDKLMSPEREFHTSHGSLATSSSPNS
TITTAAAARSAYRKMSTIDVRSEARRPSLAKFNSVSMIEAPITKVINILMAIKESGPVFL
APTLEKAIDILKNSEVFNKFQNQMKPEDQVTSELISSLMNTANKPSNSGTRRMSHDVPSS
ISSSHNKNNASYHLTQTMSTPAYSSSQSHLHYHHHHHHHQSSLSMIVPANIQKLLEDDLK
WNFNVIELERISENRPLLWLGNSIFDRFNVLQTLNCSRTVAQNWLSLIESKYRKNSYHNS
THAADVMQATAYFLMSERLKTLFDPLDQAICLIAAIIHDVDHPGRNSAFLSNSNHELAVL
YNDISVLESHHAAYAFRLTVLGPDSDRVNIFKNLDRETYRECRQSIIDMVLATEMTKHFE
HLTKFVRTFQSFNIVDDEQLTINLDKYKNIDVDDDDDNISTTTTVSDLATPENIVLIKRM
LIKCADVSNPGRPTKLCEIWANRIASEYCDQTEEEKRNHLPVVMPTFDRKNCSIPKSQIG
FIDYFANDMFEAWHSFGNFTEMIENMNINYQYWKDKLPIAEPRSRKVSESADDIKEVDEE
NNNDMTS
>A0A2X4Y2C6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Leminorella richardii|TrEMBL
MESLFQLPLASGSKVRVLQITDTHLFSGADETLLGVNTLQSFHAVLDEITGRECDYDLIV
ATGDLAQDRSFAAYQRFTAGISRLPAPCIWLPGNHDFQPAMVDAMELAGLLPSKLALLGE
DWLVILLDSQVLGVPHGELSDYQLNWLDRSLTQYASRHALILLHHHPLPSGCTWLDQHSL
RNAHMLSEVLDRHPQAKTLLCGHIHQDLSLDWNGRRVLATPSTCVQFKPHCTNFTIDNLA
PGWRYLDLYADGTVETTVCRLQSDAFLPDMDSDGY
>A0A399EHK2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Calidithermus roseus|TrEMBL
MRIAVFSDIHGNLAALEAVLADLEDIRPDIVVVNGDLINRGPQNQEVIERLWEMPYRFTL
GNHDDLVVKWRSQHESLKSLFDDPFFGATGWSAARLDKPHLDWLAALPHEVHLEALALRI
THGSPRHYREGYDERLSEEALEQIIGAYPARYLVGSHTHRPYTRQHNGTMVWNTGAVGAP
FNGDVRAQYLVLEVSDETLVPHFRQVEYDLEATLKAFRDSGMLEEGGLSAEIFYYETQNA
RSMLVPFWLWTQAQKRPLDKASWEAFRKADPERFVRSG
>A0A3Q0RNE7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Amphilophus citrinellus|TrEMBL
SEKGRTMLESGDRPSYYLSLLSPSFFFFLCLCSFDVENGLSVGRSPLDSQTSPGSGLVLQ
ANFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLHGEDMIVTPFAQVLASLRTVRSN
FAVLTHLQDRVGNKRPSSSNQPSMCNPCLTGQY
>A0A1X1DCI6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea wallisii|TrEMBL
MDSLLTLPAVNGSEIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIAAQQREYDLII
ATGDLAQDHTVEAYQHFVAGIARLPKPCVWLPGNHDFQPAMVDTLEQAGIAADKHVLLGE
HWQLVLLDSQVPGVPHGMLSEYQLEWLDRTLRIYPQRHTLVLLHHHPLASGCTWLDQHSL
RNPHQLDAVLQNFPLARHLVCGHIHQELDLDWHGRRVLASPSTCVQFKPHCTNFTIDTVA
PGWRWLTLQPDGALHTEVNRLQSDMFRPDLDSEGY
>A0A060YKD8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oncorhynchus mykiss|TrEMBL
SHILSDFHTSVITLDRIKEGTMTSCLPAPLLQTPIHMNLPFSFSSLTLSFDVENGLPVGR
SPLDPQASPSSGLVLQANYPHSQRRESFLYRSDSDFDLSPKAMSRNSSMASELHGEDMIV
TPFAQVLASLRTVRSNFAVITHLQDRPNRRPSGSNTPSMPTHTNPSIPEEPYQKLAIETL
EELDWCLDQLETLQTRHSVSEMASNKSFLRMRHHSAMATTDSQI
>A0A387HL14|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces hundungensis|TrEMBL
MRGMSRRQFVSRMSAAAAGAALWSAAAQDRALAATSARAVRIGGTTLEQAATPVGAGAYK
RLVAGPGWPLVVRGELAAGSTSRDDRRAGLASFVQFTDLHLADTESPVRFEYLAQYNDSA
HRPQETLTVRGASSLVERVNSVRQGPYTGLPFGMVMATGDNTDNHELIELDWYLTVMSGG
RITPSSGDVARYEGVQNSGSADYWNPELSFQDTYKAKGLPQIPGFLAGAVRPFDAPGLSV
PWYTTVGNHDDSIEGSLPDLGLLNDLYTGDRKIEGCDDATAAKLAYALRHNPAQAALLLA
QLLGNGGAIRKVTPDERRRPFTPAEFAKAHLNPAYAGAGPVGHGFTSDAASSGHLYYTFP
LAGGVLGISLDTTNRAGFADGSLGTAQLKWLESVLKSHSSRWYDSDGHVVRGGSTDSLIV
LFSHHTSTTMGNLLPDPYHPFEGRHDGNELVSLLQRYPNVVAWVNGHTHENRITPHGHAV
PERAFWEINTASHIDYPQHARIIELADNGDGTLSLFTTLIESAAPYRTDFADTSDRGLAA
LYRELSYNDPYATPAARLGSSADHNTELLLAHPGK
>A0A182R086|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles farauti|TrEMBL
MNEVDQAGAGCFKMKSFFRKYRSKSMESLCKPSDKAAVLTVKELESMPEAERTRPARRRY
SLLGTPPSSAEHSEMQPSRRPSYCDIRPEEERTQMPMDSGPTSRVDNGNPSLITGSKLTT
ELISSPEPHRWLLPLEASPSSTSDDNESEQRLYSRTNSAPVFRPRSYGRRSNGLKVFRFP
DILEESPIEEPMTCKRGVVQLPSSTMDISKVLIRQLSAREWRRFEAFRSLPADSIEPAFR
QQILADYDVHFYEYDEPAVVRREPPVKDAVTFAVEEEPMPGSSHRQEQSDGKRQHQLVEV
VVENGPGEDAEEIMVPSLSEEDMSAIERLVSDLKFPNLLPPNPVIKILIAFCKNDPVFEA
LVNASHRLSLEPTFVKSAETAIDAFQNPSSGGHHIIIVDARYPRTLEAEALGRSIRNSKG
SQHTTMVAVVKKSVFEKDDTAVISLLDVGYNRCIIESPHVSICSSELRQIQHSLVRPQNV
ISTQQALYTALHRSREAVIITDDTLRAQYANRASERVLNMKLDEIVGRSLNDLVTADISN
ILSHTSRYKDYDGYLTTRRKSQESSQIHVRAVPVSCIGRNPTHLVLVLESSSSALVSSNA
IGEALQTLPQGKEVPRGSLHSIRRGSFDVRSIASDGLRRTSLAKLSSLPLEAPITKVLSL
LAQVQENCSLDEAKLLDRVMEFLKREGLYSPQMKEIRTEDPVATDLIGALLTQGPTNILS
SRRSSNDSIIRGGGRPSTGSIVFNKTKESSQLSDLLQTALDWDFEIFKLEDLTEKRPLVC
LGLELFRRFDVYNTFNCDEMTFKLWLIEMEKYYHSENTYHNSTHAADVMQATAVYLQQLS
NRELKIMDRMDEATALIAAATHDIDHPGRSSAYLCNSDNTLALLYNDICVLESHHAATTF
RLTLGDDKINIFKHLDRDMYKLARSIIVDMILATEMTRHFEHLAKFVSVFGTDVESKEPL
PPDNDDNQILVRRMLIKCADVSNPTRPLKFCVEWARRIAEEYFMQTDEEKRKNLPIVMPM
FDRTTCSISKSQIGFIEYIIHDMMDAWNSFIEMPEIIRYMEFNYSQWKLFEEQGINTLSD
IKRKQMSLTEETPSSISLEEKF
>A0A0M0I112|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio hepatarius|TrEMBL
MKVTSSSSDGSIKLLQITDTHLFEATDGSLLSVNTGDSFNAVVNAILEQQCEYDAVLATG
DISQDHSAVSYQRFERGIAPLEKHCFWLPGNHDFKPNMTSVLPSQQIQHIEHVLLGEHWQ
MILLDSQVVGVPHGRLSDQQLALLEDKLSQYADRHTLILLHHHPILVGSAWLDQHTLKDA
QDFWNVVDKHDNVNAILCGHVHQDMNVMHNNVRVMATPSTCVQFKPNSDDFALDTRSPGW
RELELKRDGQVETLVKRLPQGSFQPDFNSAGY
>A0A0T9R4D7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia similis|TrEMBL
MALPTDSHNTHNYLIGGRQKQGYHLESLFKLPVASGARVRILQITDTHLFAGEHETLLGV
NTSHSYRAVLDAIIAEQYPFDLVVATGDLAQDHSVAAYQNFAKGISRLPVPCVWLPGNHD
FQPAMVDALAEAGIAPSKQVLAGEHWQVLLLDSQVFGVPYGELSDYQLEWMERCLIAYPE
RYTLILLHHHPMPSGCTWLDQHSLRNAHMLAAILTRYPRVTTLLCGHIHQDLDLDWYGKR
LLASPSTCVQFKPHCTNFTLDAVAPGWRYLDLLPDGGLETEVHRLDSDEFCPDMDSDGY
>A0A0U1KD95|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia mollaretii|TrEMBL
MESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTSHSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGIARLPAPCLWLPGNHDFQPAMVDALAYAGIAPSKQVLVGD
NWQILLLDSQVFGVPYGELSDYQLEWMERCLVAHPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGRLETEVRRLASDEFCPDMDADGY
>A0A178JGP1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio europaeus|TrEMBL
MKVTSSSSNSDSIKLLQITDTHLFEPVDGSLLSVNTLDSFNAVVAAIVEENQSFDAVIST
GDISQDHTAESYQRFEQGIAPLKNTCFWLPGNHDFKPSMNSVLPSTQIKQVEHVLLGEHW
QMVLLDSQVVGVPHGRLSDQQLALLEDKLSQYPERHTLVLLHHHPILVGSRWLDQHTLKD
AHHFWEVVEKHSNVKAVLCGHVHQDMNVLHQGVRVMATPSTCVQFKPNSDDFALDTLSPG
WRELELHSDGQLTTQVKRLPYGCFQPDFNSAGY
>A0A3C0GXE9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacteriaceae bacterium|TrEMBL
MESLLNLPVADKASVRILQITDTHLFAEKSETLLGINTWSSYQAVLDAIAAQQRSCDLIV
ATGDLAQDHSSEAYQHFAQGIAAFAAPCVWLPGNHDFQPAMFSALQDAGISPAKRVFCGD
KWQILLLDSQVFGVPHGELSEYQLEWLEAKLADVPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDAVLSRFPNVRHLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTIDTIA
PGWRWLELHPDGTLTTEVERLEGTQFNPDTASEGY
>A0A6G9WFI8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio diabolicus|TrEMBL
MQSSSDSIKLLQITDTHLFAADEGSLLSVKTADSFNAVVADVLRRNVAFDYILATGDISQ
DHSAESYQRFANGIEPLEKDCFWLPGNHDYKPNMGSVLPSPQIKAAEHVLLGEHWQLILL
DSQVVGVPHGRLSDQQLTLLEEKLAEHPERHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVERFDNVKGILCGHVHQDMNVLHKGIRVMATPSTCVQFKPNSYDFALDTTSPGWRELQ
LHACGDITTQVGRLPDGQFQPDFSSNGY
>A0A0H3PET7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae (strain NTHi 3655)|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQAVLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLSPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTQVKRIQQAEFLPNMQEEGY
>A0A8G1DB61|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Rhabdochlamydia porcellionis|TrEMBL
MVRCAHISDLHFAKPSWKIHHFFSKRWIGNANFYLRRRSQFCFENIQALPLLFKQLEVSK
VLITGDLTTTSDKKEFLMAQAFIQRLEEQGLLVLLLPGNHDQYTKADFSHKTYYRFFPSH
FSESTCNLKDDGLTVVKIGNKWSAIFLDTAIATPPLACYGFFSPELEKKLKQTLKQMPKD
HSVLILNHFPLIYNEAPEKGLKRSEALCDLIKEFPRVNLYLHGHTHRHCIADLRQSNLPI
ILDSGSIIEKKMGSWNLIELHEKEFWVESFKIVNSKWQPTSRSYFKVNNV
>A0A2H5XAS0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR17|TrEMBL
MRMEGSLLAFGAVITALVGYGVWRSVFVEPYRLAVERRLVALASLPPALDGLTIALLTDL
HLMPNGRGVELAERAVVLANAADPDVVLLGGDLVHWCGAVPHLIPVLRRLRSRYGVFAVL
GNHDHHCPWRWRTPEPWGGRPLSPDEWRQVLAQAKVHLLVNEAVPLHINGATVWLAGVDD
AYTGRADLLAALASVPDDAFVILLSHSPDIVDDPLIRRVAVVLSGHTHGGQVVLPLLGPL
FAPCRDKWRRAQGVVRVGDTWLIVSRGIAAGVPVRFRCPPEVTLLTLRQSRPR
>K7FGU9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pelodiscus sinensis|TrEMBL
MKEQHSCVGTGHLSMAGYGRMDALELAVSPVKRLRTEYSFPYLFAEEAYQKLASETLEEL
DWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEV
EIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPKFGVKTEQEDILAKELEDVNKW
GLHVFRIAELSGNRPLTVIMNTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNN
IHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALM
YNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLAD
LKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMV
>A0A6L6FA27|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia sp. wls1938|TrEMBL
MDSQLKVTANNPKVIRILQVTDTHLFADTENTLLGINTYRSYQAVLDAIAEQNLPVDLIV
ATGDLVQDQSPKAYQHFAAGIERIPAPCVWLPGNHDYPPAMVGTLKIAGISSAKQVFIGD
DWQILMLDSQLQDVAHGELSEQQLEWMKQCLDEQPTRTTLIMLHHHPLPSGCTWLDQHSL
RNSHILADYLKSYPNVKAMLCGHIHQEMDENWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELTVNEQGEKVIETQVYRLNTQEFSPDFDSDGY
>A0A4R0FDM2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. ANC 3781|TrEMBL
MTVSNSHEPQQDWTIIQISDTHLMNQEDLEFVHMNPEHSFHAVMKQIQQQYPNADAIIHT
GDLAQVPVKETYTRYLEFMQSLGIPFYQIPGNHDNIDLFPFYHNQNRVHAIHFGRWSIVL
LNSAVRDKTDGWIEEAQLHQLDQILSQFQQQFVLVACHHHPFDMKSKWIDQHKLKNTENL
IDILARHSNVKAVVSGHVHQDSLNEWKNIQFFSTPSTCVQFRPLSEDFALDEEAPGFRVL
HLKANGELHTEIHRTEKVQQKINVEISGY
>A0A5C4RIJ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus luminescens subsp. sonorensis|TrEMBL
MESQFELPVVEGTTAKILQITDTHLFASKEDTLLGINTYRSYQAVLDAILKQNANIDLIV
ATGDLVQDQSLEAYRHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILIGK
HWQLLMLDSQVQGVPHGELSEYQLEWMKKCLDKYPERYTVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQGYSRVKAMLCGHIHQEMDLDWNGVRMMATPSTCVQFKPHCTNFTLDTVA
PGWRYLELSVADNGEFGLATQVHRLESNEFCPDLDSDGY
>A0A854CW04|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSNEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNVAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAEFLPNMQEDGY
>A0A8D4R6D2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILV
TGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNVAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAKFLPNMQEEGY
>A0A5Y7AK19|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Infantis str. CFSAN000522|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>F4VJ34|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli H591|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A6J1M822|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila hydei|TrEMBL
MGCSPSTLPNSSSTAGGAGGVGNAPLPPLDANEKDGSLLFCIKLRRSRMRRCSCGAVTLQ
NQNGDGSTGSATCGDNMMCNQGLLNPLQTKNESDYEKLSTGKKDSIVTVAALGNFTHSVV
RRATGTGSTGTSGTSSSGGGRPGHRKSSLALALTPEDDSMDVYQRNLMDLKYPTVLPPNP
QLKALLVFHKSDSICEVVTLACQRHQLDVTLVKSKEEALETLHKSYATAQCYHLIIIDAR
STKGLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDALIALLDAGVNRCIAETTNLTL
CSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLNMRL
DEIISKPLGDIFVSDLSTISEQGKSIKEFDGILMVRRKNQESIPMHVRVVPVACIGSAPT
HLIFNFDIPGGGMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLP
LEAPITKENCSADEARLIDKVLDFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYS
SRRSSNDSIIRTGNSTRTATIVPAKMKANPIIMELLEESLKWDFDIFKLEEITDYHPLLY
LGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADVMQATGAFITQLA
SKDMVMDRMDEATALIAAAAHDVDHPGRSSAFLCNSNNPLAILYNDLTVLESHHAAITFK
LTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGNEMEPRELVQ
SEEETSILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYFMQTDEEKQRHMPIVMPMFD
RATCSIPKSQIGFIEYIIQDMMHAWDGFIDMPELITCMQINYSQWKKYDEQGVNTLADIM
AKQPPVGNKSSSSK
>C4L9C4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Tolumonas auensis (strain DSM 9187 / TA4)|TrEMBL
METCTLSKPDDGIVRLLQISDTHLFAETNRDLLGIATADSFQAVLDAITELPQTYDVVLA
TGDLSQDHSAASYQRFARMVTTLQKPVHWLPGNHDHRVLMQNELQVSGIRPEMQLVGDHW
QVILLDSQVYGTPHGWLSHLQLEQLEAALLQYPEKHVLICLHHHTFPIGSIWLDQHDLKN
ASDFLAVLARYPRVKAVLCGHVHQEYDQYHQGIRFLTSPSTCIQFQPLSVDFSLDTMSPG
WRYLQLYPDGRIATQVWRLEPGQFAPDLQSTGY
>A0A2A5T6N1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Enterovibrio escacola|TrEMBL
MRICHLLSQCSQTVRLLQITDTHLFADPYRSLLGVNTAASYQAVVDEIQRKNVVFDAIIA
TGDLSQDHSTASYQRFAEGISNWSQPCYWLPGNHDCQPKMRTVFEQPTLVGCDQVLMGEY
WQLIILDSQVKGLPHGRLTVEQLTMLEIALISHPKRYGLVLMHHHPLAAGSSWLDQHQLN
NQDAFWSSVEKYDNVKGVVCGHIHQALDIHHEGRRVMAAPSTCIQFLPDSSNFALDSTNP
GWREILLHQDGKISSEIGRLKGKVFCPDMHSTGY
>A0A1V3JXB9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rodentibacter sp. Ppn85|TrEMBL
MRNTFVYRTEKPIVKLLQITDPHLFKDEKNELLGVNTQASFAQVLKEIQQDNTEFDVILA
TGDLVQDSSDEGYQRFVKMVKPFGLPVFWIPGNHDFQPKMVENLNQPPMEKAKHILLGEH
WQVLLLDSQVYGVPHGELSQHQLGLLKTTLEQYPERYTLIVFHHHLVPTNSAWLDQHNLR
NSHDLFDVLAPFKNVKAILYGHIHQQVDSRWQDYQVMATPSTCIQFKADSQYFALDETQP
GWREIELHSDGTIVTNVKRIRQAIFLPNMQEEGY
>Q9HCX6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|TrEMBL
MDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLDPMTSPGSGLILQA
NFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
AALTNLQDRAPSKRSPMCNQPSINKATITV
>A0A290HCP2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sulfurospirillum sp. JPD-1|TrEMBL
MFEKAYEKLNFKSMTIGIEKLPPSFENFTMVHLSDLHVNAKTPLHALENLVAKINALSVT
MVALTGDLFDTFPSKIRAHLDILKKIKHPVYFVSGNHDLLFTCKVLSKEIEALGFTRLDN
RVLTFCRGDDRLQFVGLSDAFSHYFGIKRHEKELFTNLNPDVPAILLAHQPKDIRLTQNA
SIDLQLSGHTHGGQIYPFGYIVRLFQPYLQGLHRYGKTQIFVTTGYGSWGLNFRFRAPSE
IVIIRLTKDEHVEH
>A0A1W2PQN6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|TrEMBL
AFQGSRSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKS
MSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINK
ATITG
>A0A2P8B204|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micromonospora sp. MH33|TrEMBL
MLLARGAAIFAGLTAAGVTGYGVRTAMGPPRLDRVRIPLAKLPRGMDGLRIATVSDIHLG
PLRGRAHTERIVAMINRLDADLVAVVGDLVDGSVAELGTAAEPLRDLRSRYGSFFVTGNH
EYYSGVEEWVREVDRLGLRVLQNERQEIRARGGVLDLAGVNDVTAAGTGLAAPADYAAAL
GDRDPSRPVVLLAHQPVAAHEAAKFGVDLQLSGHTHGGQMVPFNLLVKLQQPVVSGLGEV
DGTKVYVTNGAGFWGPPVRVGAPPQVTLVELRAP
>A0A7Y1ZGN8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Halioglobus sp|TrEMBL
MPGNPSVTVTPAGDIVRIVQLTDAHLCREHGGTLLDMDTDHSLGVVIERVRRERQGLDIL
LGTGDLADGAAPEAYERLDSYFNELHEDNFWLPGNHDDRAAMEAVGGPNRLPGTISAGGW
QLVLLDSQVPGEVGGELGARELAHLEACLEEAAIAGQHVLVCLHHQPVNIGCGWLDEQMV
ADADEFFSLVDDFDCVRGVLWGHVHQEVDTVRNGVRLLASPSTCVQFAPGCEKFKADDKP
PGYRWLDLTPDGGIDTGVSRVLDVTFEVDLESGGYL
>A0A6S7BI70|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia ultramafica|TrEMBL
MKIRVLSDLHLENDEPELIPHAHADLIVLAGDIHNHAAGPRWAAQTFDGAVPVIYVPGNH
EYYDGEFSALERALYDAAAQVDNVHVLNNATLIDPQGRWRVLGTTLWTDFALYGADPGTL
AESIDAARRVMLDFRGLIQMNWPHDTHDAARDFTPADSLALHRQARAWLEGELAKPFGGK
TIVVTHHAPHRLSLAERYAQDRVSAGFVNHLPELVCAPVALWIHGHTHTSFDYTVNGTRV
VCNPRGYFDRRTGKWENSQFAWDKVVEI
>A0A4Z2IVG3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Liparis tanakae|TrEMBL
MDKTRTDGDLTEARLFFLYAAGEPSVGQFSSGSTLGVEVCKVHRRFSGNLQLPPLSWRQV
ERDRDRVRSLTPEEDPTPWTRPSSLPISTLPRIDITQADPDSLEGEHGPSVCCSPSDLQA
SPGSGLVLHPNLAAHGQRRESFLYRSDSDYDLSPKSLSRNSSIVGELHGEDLIVTPFAQV
LASLRTVRNNFTTLTNVQCASNK
>A0A1X3KY43|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli H420|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A3G8JUA3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gordonia insulae|TrEMBL
MILFAALFFALITFWLHRRLVHATDLPRPWSVIVDVVLVVLWVLALVGIATGRLLDPAWF
RIPAFVGLTWMAAVLYLVLGLVIVAIGSLIARAVARARHTPSDVAMSTRRRSVRVATAAV
VVIALATTAYGLVEAARPQVVQAEVDLPDLPAGFDGIRVALISDLHVGPARDERFTRRVV
DLVNEQRPDLIVIAGDLTDGTVAQVGPDLAPLADLSAPLGVFGVSGNHEFYADDGGRWLD
AWEELGVHTLRNQRVTVEHNGSAIDLAGIQDATAPTPYEPDLPAALADRDPSRFVLLLAH
EPRQALEASDLGVDLQLSGHTHGGQMWPIRYLVTLQQPSLQGLDRVGSTVLYTTRGAGAW
GPPVRVGAPPEITILELHKPSGR
>A0A380PVW5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia frederiksenii|TrEMBL
MGRVQKQGHHLESLFKLPMASGAKARILQITDTHLFAGEYETLLGINTSRSYRAVLDAII
AEQRPFDLIVATGDLAQDHSVAAYQNFAKGISRLPAPCVWLPGNHDFQPAMVDALADSGI
APSKHVLVGDNWQILLLDSQVFGVPYGELSDYQLEWMERCLVTHSERYTLVLLHHHPMPS
GCTWLDQHSLRNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPH
CTNFTLDTVAPGWRYLDLLPDGILETEVRRLASDEFCPDMDSDGY
>A0A509E0H1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Thalassocella blandensis|TrEMBL
MRPFHLLQITDCHLGSKPGDTLLGMNTDESLCDVLQCMQEQEHPDMILVTGDISNDGGVR
SYERFIEYIDEYFPNIPLAWLPGNHDDPDNMDQVENLPIEAHHLVAGWNMIFLDSKIPME
EGGDLQPSELKRLESELQKYFDMPTLVFLHHQVVPVGSAWVDQYIVKSHKAFFDVIDRYN
NVKVVSWGHVHQEFRKKHRDVALIATPSTCVQFSPGIDRFQVDKLMPGYRSYKLYPDGRY
TTQVHRVPPKDYKIDFDSDGY
>A0A6M4YD33|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas media|TrEMBL
METELPQAPDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQANAHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGDHWQ
VILLDTQVRGKPHGVLGDHQLAALDSALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHQGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRIASQVWRLPVGQFVPDPNATGY
>A0A752RRS4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Carrau|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A6L8LXU5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. OCN044|TrEMBL
MKVTSSSVDGSIRLLQITDTHLFEANDGSLLGVNTSDSFDAVVSAITEQNTNYEAIVATG
DISQDHSALSYQRFESGISKLNKTCFWLPGNHDFRPNMDSVLCSQQIQYLEHLLLGDYWQ
MIVLDSQVVGVPHGRLSEEQLSLLEDKLNLYPERYALVLLHHHPVLIGSAWLDQHTLKDS
ESFWKVIEKHSNAKAVLCGHVHQDMDRYRHDVRVMATPSTCVQFKPLSDDFAVDNQSPGW
REIVLHSSGNLTTEVKRLPMGSFIPDFSSSGY
>A0A8G8AJ94|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGRLTTEVHRLADTRFQPDTASEGY
>A0A2G2IPC9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moritella sp|TrEMBL
MGADISKLTVKHNVINLLQVTDTHLFATAEKDLLGVKTQLSYRHVIDAILQNQQPFDAVL
ATGDISQDNTPASYQYFAQHIKRLNKPCYWLPGNHDNIPLMADALRAEGVLADKYKVVGD
WQIVLLDSQLTGSPAGYLAPEQLLLLDEQLSAHPDKFALVVLHHNVYPVGCKWLDQHLLR
NADAFLAILAKHPQANHVLFGHVHQQLDKTYAGIHFMASPSTCFQFKPHCDEFTLDARAP
GWRYLQLHSDGSINSQVWRLSNNDFNPDLESKGY
>A0A385EYH4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter baumannii WM99c|TrEMBL
MLLHLSDLHFGTEKKECLEAIRDFCIQQQPEVIVVSGDITQRAKYEQFFKCRQYLDSLNI
PYLVVPGNHDIPLYHVWNRFFSPFTRYRYFFGELEPTLETEHFYIVGVNSIRRRYHTRGH
ISIEQIQATYERLDRGPKNKIKLVVFHQPFYTPPDNKHGIKDCPVLGKIALEKWSTTGLF
GMLHGHLHKTAIYDLTQIYSLKIDHPIFDIHAGTATSTRLYHHNPNSFNTISNEGKIQHY
WFNYDLKIFQLI
>R4YEM0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pneumoniae subsp. rhinoscleromatis SB3432|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A1R3FQW0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. 10N.261.45.E1|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLAEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHNNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPDGQFLPDFEAAGY
>A0A7I6QK10|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella sp. WP3-S18-ESBL-05|TrEMBL
MESLLNLPLAGGASVRVLQITDTHLFAEKNETLLGVNTWESYHAVLQAIHASARDVDLVV
ATGDLAQDHSAAAYQHFAEGIASFTAPCVWLPGNHDFQPSMYSTLQDAGISPAKRVLVGE
HWQILLLDSQVFGVPHGELSDFQLEWLEKRLAEAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAASLDNVLVRYPRVKHLLCGHIHQELDVEWNGRRIMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHADGSLTTDVCRLAGVKFHPDTASEGY
>A0A673YSS4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmo trutta|TrEMBL
MSWPSSFQGTTNPSIGNCVGNRRFDSENGPSAGRSPMDSQASPVLGLHPSFTTEGCRSRG
ERRESFLYRSDSDYDMSPKTMSRNSSINSEGHAEDLIVTPFAQVLASLRTVRSNFTILAN
VTTPTNKSVAFYETYQQMARETLAELDWCLDQLETIQTHRSVGDMASNKFKRMLNRELSH
LSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTLRERDRDKPMCHISGVKKLTHSSSLSIN
TTMPRFGVKTEQEDALARELDDLNKWGLNIFRLAEFSNNRPLSCIMFAIFQERDLLKTFR
IPVDTFVTYVMTLEDHYHANVAYHNSLHAADVTQSTHVLLSTPALDVRTTFHHTLSLLCV
LKRQRQSLRKLVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDHYTDRIQVLRN
MVHCADLSNPTKPLVVYREWTERIMEEFFRQGDKERERGMEISPMCDKHTASVEKSQVGF
IDYIVHPLWETWGDLVHPDAQDILDTLEDNRDWYQSTIPQSPISPPPIPLGQDKRLNACI
DKFQFKLTLDDDTEGGQEEEEEEEEEEEEEEAEEEEERKTTPNHMVLDCIQGEEEGEDVV
KDEREGDIIEEEGEDVVKDEREGDIIEEEGEVGMEEEEEEKRGVLQRAQSGVEIHSGTSP
VEDEEEEDSSSPADDT
>A0A2R5LBA9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ornithodoros turicata|TrEMBL
TPEDGKKGTVALKFGSMYLTVPTVRVLFVFMKEDNQYQALKWSAEKMHYECQLSTSADAA
VESYLNSQPHLVFIDARSRNAIDPVTLCRTIRGFRGSQFSCIVAVVKKGLAEKEDAAIIP
LLKSGYNRWFTESSSYGVCLNEMIQIEHNDLISLWKLRASEALFSALHFSRDGVIVTGPN
HEIQFMNRAAEKLVGYSVEEMLGANAQELHRTDSLKGDVVQTIAAQIKKGKEWEGTLFHK
RKSGECIPMWSKIAPVEIHSGMSDHLVYIKECPFFMEKPFSPDADLQPYSYNASCKSSRK
ASCDVRSLCSEVGMNRRQSFAKFHAMTIEAPITKVINMLVATQDNSPAVVVQALDRVLEI
LRSTELYNPQLGVGGQGRSEDQMTSDLVTGLINTGQRPTGVRRLSHENAVMKVNVTTNQQ
AGGSLPSLSTAPPKIRELLENDTVWEFDIIELETISGRRPLIWLGLSLFSKMNVHTSLNI
DDSTIRNWLQVVEAHYLDNPYHNSTHAGDVLQATAYFLIKLRKKDIFDPLDEAICLISAV
VHDIDHPGKSSPFLCNSDNELAILYNDRSVLESHHAAFAFKLTLSDEKVNIFQNLDRDTY
RTVRLSVIDMVLATEMTKHFEHLSKFLNAFQKPIQGDDAFDPDSMADQDQANSLRSPENI
ILIKRMLIKCSDVSNPARPINMCIQWAHRIAEEYCAQTDEEKRRGLPVVMPAFDRATCNT
PNSQTGFITYFVRDMFRAWSDFGEFPELMEYIEKNFIYWKDKETNRAN
>A0A809HU08|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia sp. P2ACOL2|TrEMBL
MESLFKPTVASGARVRILQITDTHLFAGENETLLGINTYRSYHAVLDAILAQQRDFDLVV
ATGDLAQDHSLAAYRHFAEGIARLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLVGD
HWQVLLLDSQVFGVPHGELSEYQLEWMERCLQAYPERYTLMLLHHHPLPSGCTWLDQHSL
RNPHMLGAVLLRYPKVNTLLCGHIHQELDLEWQGRRLLASPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRIETQVFRLENDDFRPDMDSDGY
>A0A6C8GX30|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Uganda str. R8-3404|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>W1IUW3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus szentirmaii DSM 16338|TrEMBL
MERLLEIPVAENTTARILQITDTHLFANKRDTLLGVNTYRSYHAVLDMILEQKTDIDLIV
ATGDLVQDQTIGAYQHFAEGISRLPAPCVWLPGNHDYQPAMVDTLAAAGISPSKQIFIGQ
HWQLIMLDSQVQGVPHGELTDYQIEWMKKCLDEHSERHAIVMLHHHPVPSGCTWLDQHSL
RNTSELSEALKGKAQVKAILCGHIHQEIDEMWNGIRVMATPSTCVQFKPHCTNFRLDTVA
PGWRYLELSVTGNKDATLRTQVHRLQSNEFCPDLDSDGY
>A0A0K0HEN4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella bongori (strain ATCC 43975 / DSM 13772 / NCTC 12419)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLTDAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELHANGLLETEVHRLQDTRFRPDTASEGY
>A0A444GNG1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Endozoicomonadaceae bacterium GTF-13|TrEMBL
MQITDCHLFADADGRLMGVDTSQTLDWVLELARSLPSPDRLLLTGDLAQDGTPDSYRLLR
ERIAPLNVPSHWICGNHDNALAMAEALADQPQTLSKRIVMGSWQLLMLHSQVEGEVGGAL
AEAELELVERSLRAFKGHSLICMHHHPLAVGSQWMDRIAIANQQQLWERLALAQGQVILL
CGHVHQHQERRHQGVTLLTTPATCFQFAPLSDSFGVTEEMPGLRTLELYDDGSFDTQVHR
VSPHELTINRELMGY
>A0A6A7SH78|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|wastewater metagenome|TrEMBL
MESTNSEGARGLAFAHLSDPHLTSLRDLRRRELIGKRLLGYLSWRRGRRHVHCDGILAAL
QRALATHPDEEIAVTGDLTHLGTPDEYREARDWLAALGPGPRVTVVPGNHDLYVPVRWED
TLAEWAAHMCGDGDGDDRPGFPFERRRGPVSFIGVNTAYPSAPLLATGRIDGDQLDGIGR
ALARAGEAGRFRVVLMHHPPQPDAVSRRKSLLAAGRFRALVRRHGAELVLHGHAHRRLRG
EIDGPRGPVPVLGAPSVSQRTHDPARNAAYHRCVVTPTPTGWQLAVTVHAYDTETGDFTT
RADAGHTLEIPRQSA
>A0A6A7SAF2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|wastewater metagenome|TrEMBL
MRIQPVSDLHLETRDGATLEDMVPPADVDLIVLAGDIATGTHGVEAAARLSADRNTPVVY
VLGNHEYYGWHFPELACDCRETARALRERGTGEVHVLEREVLHLGSVRVVGATLWTDYRL
HTHGDVQQVGRNRRIAARQLADHHFIHTRDGHFRPEDAQAAHQHTREWLEAVLAETWDGP
TVVVTHHAPVPQLSHPGYPGDGLAAAFASDLSGLIHMHPPALWISGHTHANADLTIRGTR
FVANQPGYPHEETASIGRAAFTPDKVVVVEPED
>Q1ZM48|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium angustum (strain S14 / CCUG 15956)|TrEMBL
MQTYSLPQTNPDSVVLLQITDTHLFANESGALLGVATQQSFHAVLNAVDASTRKFDAIVA
TGDISQDHTPDSYQRFAEGIARWEQPCFWLPGNHDYQPTMASILPSEQIKDSEQILVGEH
WQVVLLDSQVAGVPHGELSHHQLALLDHALSLYPERHALVLLHHHPLPAGSAWLDQHQLH
NSNALWQVIDKHPQVKAILCGHIHQELDRIHRGVRVLATPSTCIQFLPDSDDFALDQVTP
GWRYLELTATGDIITQVERLEGDVFQPTFDSAGY
>A0A4V2DSR9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. WCHAc060033|TrEMBL
MNAEKLQLTEFHKDRVIIQITDTHLMDRPEAEFVGINPEENFHAVMDDIKQQYPHIDAIV
HTGDLAQAAFPETYDRYINYMKAFGVDFYHIPGNHDNLRFFPFHTPEPSPAVVSIGQWRI
ILLNSAVSGQTDGRIQNEQLLELKKILAQLQDCFVIIACHHNPFEMRSKWLDQHKLKNAD
ELKAVLEPFQNIKALIHGHVHQESLNEWNWIPFISTPATCVQFKPLSQEFAFDQIAPGYR
CLHLKASGEFETVVHRLKNFKVTINEEISGY
>A0A7J0AJ57|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MKILHLSDTHGCHHRLRGLPEADIVVHSGDFCMVGSEQEALDFLNWFCDLPYRHKIFISG
NHDDSLYGANVDGLDDNVHYLCNSGVELDGLKFYGVPMFMGDCVTDRQSRNYAKIPSDTD
VLITHSPAYGILDFDDNVNYGSEEILERLAHLQLKAHLFGHIHARHGVVAQHGTIYSNGA
IMAADYTRLNPPNLLSI
>A0A831RHL1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chromatiales bacterium|TrEMBL
MLARQKARRFPSPAHGDPVPPHWGAVRNGAGWPSGPPAESLRVLQITDTHLYRDADRTLL
GINTQRSLEQVLKQAWYEHGPADLVLATGDLAHDHSREGYARLRALLHSLDAPGYWLPGN
HDDPQVMREVLAGAGACDPRSVRVGHWQIVLLDSRIADGGDAGRVAHAGLRSLDEDLGRY
PDHHALVCLHHQPVPIGSRWIDAIGLQNAAELFAVLDRHPQVRAVLCGHIHQEFEMRRAG
VRILGSPSTCFQFRRRSDEFALDSAAPGYRWLALHVDGGMDTGVGYLEDFAAAVDMASTG
Y
>A0A8I1E567|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas rhodesiae|TrEMBL
MPSVSTVSPDASALLVQLSDSHLFAEGDATLLGMNTRESLQRVIELVREQQPSIDLMLAT
GDLSQDGTLESYQQFRALTAAIDAPARWIPGNHDEPLIMAQAAEHSDLLEPVVDIGHWRI
TLLDSAVPGSVPGYLEDQQLQLLAQSLSEAPDRHHLVCFHHHPVSFGCAWMEPIGLRNPE
ALFAVLDRFPQVKAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRMHADGRLETGVERLKDFAFTIDYGSNGY
>A0A4S2KQ32|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Temnothorax longispinosus|TrEMBL
MGCKISILECMRGKVEQEKSISSATSSSLVTSDTTETDKNQDSLYLAFGKSHFIEEDDGK
VAQRKTDALDIVAEKDEKTPFQDSTLDENGDYLTIKGPQDLSNYLLTTNVPSIVKILLVF
SKDDPQLDILANTARRLGWSVSVAKDAEKAIELFQNRAHELVIIDHRGHHAAEGDAICRA
IRSSPVYHNSVIIALVKKSYFMLDEKDHIVALNLLETGFSRALIECSHEGILINELVGIY
TSSLLPRTQLAAAHALYLALDRCRDMVHVTNDKNIVQFLNKVSEKLLGYKTEEMMGRNLS
EIVFYENSALMEQQLAKGREFEGNMNCKRKNNQMITINCRIIPFCITLKKPSHYIYVYDT
TYLSENSAPISPASSPLHPPLKTSILSNARKSSDVRSGVSEGRRRSSLQKLHTLQLEAPI
TKVITLLSNAVTDTTNPETAAQIDKAIDILKTTELYVPHLKEDRAMYSDPVATDLVGALL
ASPRTAWESRRSSSDSARLSTIKAIAYPANSRVQVKNFRGPQELMDILDNSLDWNFEIFK
LEVLTEKRPLVFLGLTIMNLYQVPATLHCDEKTLQNWLAIIEHSYNAENSYHNSTHAADV
MQATARFMQSKRLKEILEPLDEVAALIAAAAHDIDHPGRSSQFLCNANSRLAILYNDLSV
LESHHAALTFKLSLSDDSVNIFKNLDRDAYKLLRQNVIDMILATEMTKHFEHLAKFMNVC
SARIGDGQETYSDSLDMSVVLQPDNVILVKRMMIKCADVSNPTRPLKCCVEWARRIAEEY
FNQTDEEKKLKMPVVMPMFDRMTCSIPKSQIGFVDYIINDMIEAWDVFIDMPEIVGYMRH
NYEKWKEYNEQGISTLQDVEKLQQHPEMQIPRLS
>A0A1R4L9B0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio ruber DSM 16370|TrEMBL
MDVSFHTEHLESIKLLQVTDTHLFASDEGSLLSVNTANSFKAVVQEVISRNVDYQLILAT
GDISQDHSEASYQLFVDSIAPLLKPCLCLPGNHDEQNAMKTILASAQIIQPRHVTVGAHW
QMILLDSQVSGVPYGYISPEQLQQMDDILRKSQAKHTLILLHHHPLLVGSRWLDQHTLKN
SDAFWEVLLKYPHVKGVLCGHVHQVMERDYHGIQVMSTPSTCVQFKPRSDEFALDLVSPG
WRELTLHPGGELTTHVGRLKQGLFLPDFSANGY
>A0A0E1M1J5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli 1303|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7Y0VDN5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. WS 5406|TrEMBL
MPSVSAVNPDAVLLVQLSDSHLFADADATLLGMNTRESLQRVVELVRAQQPAIDLILATG
DLSQDGTLESYQQFRDLTASLGAPARWIPGNHDEPQVMAQAAMHSDLLEPVVDIGNWRIT
LLDSAVPGSVPGYLQDAQLQLLAQALSEAPGRHHLVCFHHHPVPIGCEWMEPIGLRNPEA
LFAVLERFPQTKALLWGHVHQEIDSERDGVRLLASPSTCIQFAPGSEDFQVSEQAPGYRW
LRLHGDGRLETGVERLVGFAFTIDYGSNGY
>A0A5E4IJR8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MLDSQLHEKQEINPNLLNDQKAWLEKDLGQTKKDWKVVFWHKPPCFIRAYQTNEAIKAAF
TPIMDKYHVDIVFNGHNHAYSRTYPINNDSIVGSPALGTVYVTTGRSGAKYYDDNEPKVW
SANFFDPQDMPNYLVVDVNGYRMEVKNYKMDGPLVDDYIIDKTNGDTPRTAVPPKYNKPR
LVVNGVFLNEPMMPTSPSRINGKWYFPIKPVVEFLGGSESVSGENETLSLIVKDYLDPNV
IWSDKKVHTIVLTNASTKATMDDVTISLPDSVVVDRGNNFLISADDMKTLCGFTWRYDSD
WNILLLINPSRPGE
>A0A508T930|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bradyrhizobium ivorense|TrEMBL
MKIVQLTDPHLVPTGTLLRGIDPEARLRACLTEIEAHHLDAAALVVSGDVTDLADRLSYE
LFRDILSEFVLPPLHVTVGNHDRRSMFAEVFPEHLAADGYAHSRFRLRDHVGLLLDTWTM
GTHGGAFDTVRLEWIRTQLAEGSEPILMFMHHAPIRVGLKRLDRIALQGEDEFWDVIAPF
KSRIRHMFFGHMHRNVAGSWRGIPFTVAAGLTHQVMLDFQTDIVRHIEVEPYFSIILVND
RDIVVHPHAIRDARIIDIVPDTTAPPYRL
>F7YLQ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio anguillarum (strain ATCC 68554 / 775)|TrEMBL
MNVSPTLDNSDSIKLLQITDTHLFAPDDGSLLSVNTVDSFHAVVAEICAQHVEFDAILAT
GDISQDHSAESYLRFSRGISSLEKTCFWLPGNHDFKPNMGAVFPSEQIQQSEHVLLGEHW
QMVMLDSQVVGVPHGRLSDQQLALLDEKLSTHHQRHTLIVLHHHPLLVGSAWLDQHSLKD
SDAFWNIVTQHRNVKAVLCGHVHQNMDKLHHGVRVMATPSTCVQFKPNSDDFALDRTSPG
WRELTLSADGQIETQVKRLANGAFQPDFNANGY
>A0A508SVH6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bradyrhizobium ivorense|TrEMBL
MRCLVVADLHYSLPQFDWLLAAAPQFDLVIFAGDALNLGSAVDFRAQIVVVTKYLARLAS
LTRVIFCSGNHDLDERSADGEKIARWVAGIREFGIVCDGDNLTIGDTLFTVCPWWDGPLV
KARIDDQLREAAALPHRRWVWVHHAPPADSPTSWGGKRFFGDVELVRWIAHHHPEMVISG
HVHQSPFIPSGSWFDRIDTTWVFNAGLQPGRPPVYIVLDLDRSEAFWLSAGVAQSIDLKA
PLQRPAASLREAPDWLRSLDRIADPSLARPASAAG
>A0A8C1FIE4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyprinus carpio|TrEMBL
MASESPGGSPLSLFLSTFTWNGRQLDINSLKGKKRKRWFRSHSFDVDNGTSSGRSPLDPM
ASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQV
LASLRTVRNNFAALTNVQQERANNKRSPMCNPPPITKTSYTGVASSLLYFKYCHANSTAV
LF
>A0A8C1DTP8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyprinus carpio|TrEMBL
GSLTHQHRERERERLTDRLHSRQQRLDPEYISVCLLPDESYQKLAVETIEELDWCLDQLE
TIQTYRSVSDMASNKVRRQLVCSHFTSALLQTAGHLYAFFHRNSNIKFQYYGISAKPLFW
NFSFMNVLPNF
>A0A182SHZ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles maculatus|TrEMBL
LRQIQHSLVRPQNVISTQQALYTALHRSREAVIITDDTLRAQYANRASERVLNMKLDEIV
GRSLNDLVTADISNILSHTSRYKDYDGYLTTRRKSQESSQIHVRAVPVSCIGRNPTHLVL
ILESSSSALVSSNAIGEALQTLPQGKEVPRGSLHSIRRGSFDVRSIASDGLRRTSLAKLS
SLPLEAPITKVLSLLAQVQENCSLEEAKLLDRVMEFLKREGLYSPQMKEIRTEDPVATDL
IGALLTQGPTNILSSRRSSNDSIIRGGGRPSTGSIVFNKTKESSELSDLLQTALDWDFEI
FKLEELTEKRPLVCLGKCQRQHLTRDVSPVCFVCTIANRYHLLLTPALTLSLSLFFALFI
QPAGLELFRRFDVYNTFNCDEMTFKLWLIEMEKHYHSENTYHNSTHAADVMQATAVYLQQ
LSNREIKIMDRMDEATALIAAATHDIDHPGRSSAFLCNSDSSLALLYNDICVLESHHAAT
TFRLTLADDKINIFKNLDRDMYKLARSIIVDMILATEMTRHFEHLAKFVSVFGTDVESKE
PLAPDNDDNQILVRRMLIKCADVSNPTRPLKFCVEWARRIAEEYFMQTDEEKRKNLPIVM
PMFDRTTCSISKSQIGFIEYIIHDMMDAWNSFIEMPEIVRYMEFNYSQWKLFEEQGINTL
SDIKRKQMSLNEETASSISLEEKF
>A0A7C8LYV6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Halodesulfovibrio sp. MK-HDV|TrEMBL
MSDFWICIGDIHDEIARLKDIPELAQARGVIISGDLTMAKGIPAARRVIDAVASINPVIY
AQIGNMDKPEVTEFLQEQGCNIHRSVAELTPEVAIMGVGTSSITPFNTVSETPDDTLGEW
LDETYAKTMQYDATVVVVHDAPFDTSCDDLGNGVHVGSKAIRAFIEKAQPQLVLCGHIHE
ARSVDSIGKTTVINTGMLSDGGYAKITVKDSTLYAELCMM
>A0A0D0HUK7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio harveyi|TrEMBL
MQSSSDSIKLIQITDTHLFAADEGSLLSVRTADSFEAVVKEVLHRQVQFEYILATGDISQ
DHSAESYQRFAEGIAPLEKACFWLPGNHDFKPNMGTVLPSPQIQSVEHLLLGEHWQLILL
DSQVVGVPHGRLSDQQLSLLEEKLSDYPDRHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFENVKGILCGHVHQDMNVLYNGIRVMATPSTCVQFKPHSDDFALDTECPGWRELE
LHPSGDISTEVNRLTDGQFQPDFTSNGY
>A0A7X2RRM9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas karstica|TrEMBL
MPSVSILNPDAAALLVQLSDSHLFADAEGMLLGMNTRASLQRVIECVLAQQPQIDLLLAT
GDLSQDGTLESYQAFHDMTRQIPAPARWIPGNHDEPLIMARATVQSALMQPVVDVGNWRV
TLLDSAVPGSVPGYLQDQQLQLLAQSLSEAPSRHHLVCLHHHPVSIGCAWMEPIGLRNPE
AMFAVLDRFPQVRAVLWGHVHQEIDRERKGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERIEGFAFQVDYGSNGY
>A0A5Y3AX50|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERETLLLLHHHPLPAGCSWLDQHSL
RNAAELDGVLANFPRVKYLLCGHIHQELDLDWHGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>S9X1E0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Camelus ferus|TrEMBL
MVLDQGIHSEGKEGNGEGSKEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKGT
SELRFMIIAFVSVNLGTKVQFSEIIKLQ
>S9WJI5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Camelus ferus|TrEMBL
EESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKSMSLSRKLPKSVPLLPMKEKAE
GGACSCVILTKHFTSGYKCAQQVEMAQLSGSQDLTKPEDARANLCRSQ
>A0A3L8D7R8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ooceraea biroi|TrEMBL
MFGYVARRPPNHVDIEYANGPGARAETCLTESSVSTYIRSSARRGSSSAKAHLDRLRSTD
AIDKYITEVDMAQDNLYPAFNEIHFVAEEDHYRVAQCKTDAFDIVDEKDEKNPFGNSAYD
ENGDYLIKGPQDLDTYLLTTTVPSIVKILLVFNKDDQQMDILATAARRLGWSVSVAKDAE
KAIELFQNRAHELVIIDHRGQRADEADAICRMIRSSPVYHSSVIIALVKKSYFMIDEKDH
IVALNLLETGFTRALIECSHEGILINELVGIYTSSLLPKTQLAAAHALYLALDKCRDMVH
VTNDKNIVQFLNKVSEKLLGYKVEEMMGRNLSDIVYYENFTLMEQQLSKGREFEGNMNCK
RKNNQMITINCRVIPFCTMLKKPTHYIYVYDTTYLSENSAPISPISSPLHPPQRTSILSS
ARKSSDRSGISEAGRRRSSLQKLHSLQLEAPITKVITLLSNAVTDTTNPETAAQIDKAID
ILKTTELYVPHLKEDRAMYSDPVTQDLVGALLASPRMSAWDSRRSSSDSARLATIKAITG
TNNSRMQITSFHAPQEIAEILEKSLDWDFQIFKLEVLTERRPLVFLGLAIMNLFRVPAKL
NCDERTVQNWLAIIEHNYNADNSYHNSTHAADVLQATAKFMQSKRLKEILEPLDEVAALV
AAAAHDIDHPGRSSQFLCNANNRLAILYNDLSVLESHHAALTFKLSLSDDSVNIFKNLER
DTYKMLRQNIIDMILATEMTKHFEHLAKFMNVCSARIGENQETYSDSLDMSVVLQPDNVI
LVKRMMIKCADVSNPTRPLRCCIEWARRIAEEYFRQTDEEKRLKMPVVMPMFDRMTCSIP
KSQIGFVDYIITDMIEAWDVFIDMPEMVGYMRQNYERWKEYNEQGISTLQDVEQLQQHPD
LHIPRLSN
>A0A427WNP8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter denitrificans|TrEMBL
MARIHSLTRRDDAPAMLVQVTDSHLFGEAGTAMLGVDTDASLRAVLRQIEADGRHPDLLL
ATGDLSQDGEAQAYRRFASILSEAPALDRACVRCLPGNHDLPAVMRQELAEWSAPVTDVG
AWRVVTLDTTVPGSNAGHLPDSQLDMLEAALAAAPGRHTLVAMHHNPMQIDSHWHDTMMI
DNPQALFKLLTHWPQVRVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNMA
PGYRWIKLYQDGSMATGVRRVQDALWHPALAASAKAQAA
>A0A223Z0Q8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methanothermobacter sp. EMTCatA1|TrEMBL
MILVKILAVSDLHGSNIPELHSYLKNNRVDIIVVAGDITHFGPPELAEELLNELASHKIP
VVAVPGNCDPHGIASRIENSRAINIHARTLNIKNVAFCGLGGSNPTPFNTPLELGEDEIR
SELDKLLENLKGNDRLILVTHAPPHGTEVDRIPSGDNVGSTGVRDVIEKHQPCINICGHI
HESPGVERLGETLIVNPGQLSEGRAALIEIDDDGSVRAEILNLKSS
>A0A8D4ISP3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mergibacter septicus|TrEMBL
MSGIYQHTSVSDVVKVLQLTDPHLFADSKGELLGINTLESFKQVVREVIKSNFAYELILA
TGDFVQDDSREAYQHFVQQVSPLIQQTELKPLFWLPGNHDFQPNLLEVFQYSKEIYPEKH
LLLGEYWQVLLLDSQVAGAVYGKLSQEQLQWLDQQLALYPQRHALIAFHHHLVPTNSAWL
DQHNLRNSYQLLEILQHHQQVKVLMYGHIHQAVDTNWYGYRVLATPSTGIQFKPDCAQFT
LDNLQPGWREISLYPNGEIVTTVKRIEENLFLPNVNVSGY
>A0A508WNS5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sinorhizobium medicae|TrEMBL
MTKLIIFSDLHMVPEGGTIIGLDPHRRLANGIAHVNRFHADADLVIFAGDLAHAADRASY
ERLQALLRELMPPAALMIGNHDRRELFLDVFAEAVTDANGFVQQAIDFPDCRAILLDTLF
APPYDYPVSHAGHLCQTRLAWLDRQLGEAGDRPALIFMHHPPHASGFAGMDMIRLVNEDE
FYALVKRHGNVRHIFAGHVHRTISGSSRGIPFSIFKSPVHQQPMPFATADASLSVDEPAA
YGIALVTPDGVLVHTEDYEIARRDAMGT
>A0A5K1JD87|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Collinsella aerofaciens|TrEMBL
MKILAVADTEERCLWECFRKERFEGVDLILSAGDLDPDYLEFLVTVINKPLIYVRGNHDD
RYARHAPGGCICVEDTVYVYRGVRIAGLGGSMRYRNGANMYTEHEMAKRMRKLSRKVRMV
GGCDILLTHAPAAGMGDLDDLPHRGFECFNTALESWNPDYMVHGHVHQCYGQNFQRERRH
ACGATIINACGYTQFELDEAHYPIRGWQAAWLNSQTMRRELKRHEAIESSTARTPW
>L0MLI0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia sp. FGI94|TrEMBL
MESLFKLPVASGAKVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAVRAQQREFDLVV
ATGDLAQDHTPEAYRHFADGISQLPAPCVWLPGNHDFQPAMVDALAAAGITPSKHVLLGE
HWQVILLDSQVFGVPHGELSEYQLEWMERCLQAYPDRYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAVLLRYPKVNTLLCGHIHQELDLSWQGRRLLASPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVCRLDNDDFRPDMDSDGY
>A0A3Q0H6K9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alligator sinensis|TrEMBL
MQDWHPPHLEPGEGQELSFDIENGLASARSPLDPQASPSAGLVLQGPFPHSQRRESFLYR
SDSDYDLSPKSMSRNSSIASDLHGEDMIVTPFAQVLASLRTVRSNVAALTHLQDRVTNKR
TTSNNPAPTCKPSLSEDAYQKLAVETLEELDWCLDQLETLQTRHSVGEMASNKFKRMLNR
ELTHLSETSRSGNQVSEYISSTFLDNQHEVEIPSPPPKEDKEQAQRPMSQISGVKKLMHS
SSLSSASIPRFGVKTDQEGPLAKELEDANKWGLDMFKVAEYSGNRPLTVIMYTIFQERDL
MKTFRIPPDTFITYMMTLEDHYHADVAYHNNIHAADVAQSTHVLLSTPALEGTGPSTPGG
VHGPGDHGCHLRQRHPRRRPPRRFQPVPHQHQLRAGADVQRCLRPGEPPPGRGLQAAAGG
ELRHLPEPQQEAAAVAAQDGHRHGAGHRHVQAHEPAGRSEDHGGDQEGDQPGRPAARQLL
GPHPGAAEHGALRRPEQPHKAAGAVPAVDGPHHGGVLPPGRPGAGEGHGDQPHVRQAHGL
RGEVPGRLHRLHCTPAMGDLGRPGASRRPGDPGHAGGQPGVVPEHDSPQPLAPARGSRTQ
PRQVRVGADAGGGGRVGARGG
>A0A1B6E555|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clastoptera arizonana|TrEMBL
RTDVLVRDEDCDTQVNELAAESNCEPLCHRLQQIKTNSPKQHAFRVLLVFAKDDSACSTL
SGASEHLGFSREVASTLEQALELYQAHSSPPQIVFIDMRFSWFHGEKICRSLRAVKKSNH
VIFVAICKKNVVDKDEKELRSALKLGFNRVLVEPLSITQCVCELVQLAHGQLDLHSILAQ
NEAIYLALDKSRDLVLVTDSLHVIQYVNRTWCQVLGYKSEDLIGRSLHSFHQLGNMDPVT
RQLEKGFDWEGKISWRSKSGENITLQCRAMPYQAIGSEPTHYVYVQDNPLENHIYPRGSI
PSIRKGSYDLKSINSEGAQSARRQSLAKLHNLPLEAPITRVISLICAAQENSTGQVVQIL
DKVVDILRTTELYSSHLKADNLRCEDPVTSDLIGALITQGPVPVSTTRRSSNDSAAVKAQ
QAGLSGNKPIFSMSASPQLKELLDTSLQWDFNIFKLEEITGKRPLVYLGMNLLMHFDVHK
TLGCDEKTLYNWLTVIERNYHLSNTYHNSTHAADVLQAMAGFLEKERIKRLVDELDEACC
LIAAATHDIDHPGKSSAFLCNAGNELALLYNDVSVLESHHAALTFKLTLRDDRVNIFKGL
ERDTYKVARQSIIDMILATEMTKHFEHLAKFVSVFNKPSPTSEDGNCDNRVS
>A0A502IVP8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas caspiana|TrEMBL
MPSVSILTTADSALLVQLSDSHLFAETDGTLLGMNTRDSLQKVIELVRLQQPQIDLIIAS
GDLSQDGTLESYQQFRDLTRQLDAPARWIPGNHDEPQIMAEAAVQSALLEPVVDVGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPD
ALFAVLDRFPQVRAVLWGHVHQEIDQDRKGVRLIASPSTCIQFEPGSDDFKVSDQAPGYR
WLRLLPDGQLETGVERVTGFDFQIDYGSNGY
>A0A4Z0DRI7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia proteamaculans|TrEMBL
MESLFKPTVASGARVRILQITDTHLFAGENETLLGINTYRSYHAVLDAILAQQRDFDLVV
ATGDLAQDHSLAAYRHFAEGIARLPAPCVWLPGNHDFQPAMVDALADAGIAPSKQVLVGD
HWQVLLLDSQVFGVPYGELSDYQLEWMERCLQAYPERYTLMLLHHHPLPSGCTWLDQHSL
RNPHMLGAVLLRYPKVNTLLCGHIHQELDLEWQGRRLLASPSTCVQFKPHCTNFTIDEVS
PGWRYIDLLPDGRVETQVFRLENDDFRPDMDSEGY
>A0A7U7FJF8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia enterocolitica (type O:5,27) str. YE149/02|TrEMBL
MESLFKLPMASEARVRVLQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGISRLPAPCVWLPGNHDFQPAMVDALANAGIAPSKHVLVGD
NWQILLLDSQVFGVPYGELSEYQLEWMERCLMAHPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLNWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGRLETEVRRLASDEFCPDMDSDGY
>A0A7Y0ZKF6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. WS 5010|TrEMBL
MPSVSTVNPDAPALLVQLSDSHLFAEADGTLLGMNTRDSLQRVIELVRAQQPQIDLLLAT
GDLSQDGTLASYQQFRDLSQQLGVPARWIPGNHDEPQVMAQATMGSALLEPVVDVGNWRV
ILLDSAVPGSVPGYLAEPQLQLLAQALSEAPGRHHLVCFHHHPVPIGCPWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERHGVRLLASPSTCIQFAPGSEDFKVSEEAPGYR
WLRLHPDGRLETGVERVKDFTFTVDYGSNGY
>A0A5E6XC72|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MRESLLVNRPFLVAQISDLHLKAGQRLTYGVVDTLGALRRAVDHLNASQPRPDIVVISGD
LVDFGRADEYAVLHPEIARLHMPCYLVPGNHDTRAPLLEAFRDHAYLPSSAEGPLDWVVD
EHPLRLIGLDSTIPGGHGGQLLDSQLQWLDEQLTRRPDAPTLLILHHPPFISGIGHMDRE
PFINAAALENVVSRHPQVERLLCGHLHRPMQRRFGGSLSCVCPGTSHQIVLDLQDAAPAY
FNLEPAGYLLHRWDAQHGLISHNGVFGDYPGPYPFYDAHGLID
>A0A0U5L0W3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia gerundensis|TrEMBL
MDSLLTLAVTSHANIRILQITDTHLFAGKHETLLGVNTWDSFNAVLDAISAQQDAFDLIV
ATGDLAQDHSTEAYQHFADGVARLGAPCVWLPGNHDFQPVMFETLAAAAINDAKQILLGD
SWQLVLLDSQVSGVPHGMLSDYQLEWLDNALAAVPDRHTLVLLHHHPLPSGCTWLDQHSL
RNSHMLDELLQRYPQAKNLLCGHIHQDLDVEWNGRRVMASPSTCVQFKPHCTNFAIDSLA
PGWRLLELYADGSLSTQVKRLATQAFSPDLDSDGY
>B6ELZ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aliivibrio salmonicida (strain LFI1238)|TrEMBL
MLSETLLNKKNGPIRLLQITDTHLFALPEGALLGVSTLKSFQSVVEQVQQQSPHFDAILA
TGDISQDHTVQSYQHFVEGIEPLKKPCYWLPGNHDYKPSMGGVLPSPQIKDCEHLLIGEH
WQVVILDSQVVGVPHGALSTEQLQLLDSALSQHSERHSLILLHHHPLPAGSAWLDQHQLK
DNEVFWEVLAKHRNVSGILCGHIHQEMDCIVNNIRLMATPSTCVQFLPDSNDFALDSKAP
GWRILDLLPNGEIVTQVYRLEQCEFSADADAGGY
>A0A8H9BB43|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia albertii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYLHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCRWLDQHSL
RNAGELDNVLEKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>B6XFX4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia alcalifaciens DSM 30120|TrEMBL
MDSQLKVTANNPNVIRILQVTDTHLFADTENTLLGINTYRSYQAVLDAIAEQNLPVDLIV
ATGDLVQDQSPKAYQHFAAGIERIPAPCVWLPGNHDYPPAMVGTLKIAGISSAKQVFIGD
DWQILMLDSQLQDVAHGELSEQQLEWMQQCLDEQPTRTTLIMLHHHPLPSGCTWLDQHSL
RNSHILADYLKNYPNVKAMLCGHIHQEMDENWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELTVNENGEKVIETQVHRLNTQAFSPDFDSDGY
>B4J7C7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila grimshawi|TrEMBL
MGCSPSTLHNSSSTTEAPGGVGGVGGGGNAPLPLDGNEKDGSLLFCIKLRRSRMRSCSCG
AVTLQNQNGDGSTGSATCGDNIMCNQGLLNPMQTKNESDYEKLSTGKKDSIVTVAALGNF
THSVVRRATGTGSTGTSGTSSSGGGRPGHRKSSLALALTPEDDSMDVYQRNLMDLKYPTV
LPPNPQLKALLVFHKSDSICEVITLACQRHQLDVTLVKSKEEALETLHKSYATAQCYHLI
IIDARSTKGLDAEHIARAIRHTHGHHLTTIITVCKKSFFEKDDALIALLDAGVNRCIAET
TNLAMCSVEMKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVYRIQYANRATERL
LNMRLDEIISKPLADIFHTDLSIISEQGRSIKEFDGILTVRRKGLQDGIPMHVRVVPVAC
IGSAPTHLIFNFDVPGGGLDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLA
KLTSLPLEAPITKENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPTATDLIGALLT
GPSVYSSRRSSNDSIIRTGNSTRTATIVPAKMKANPIIMELLEESLSWDFDIFKLEEITD
YHPLLYLGMEIFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADVMQATGA
FITQLINKDMVMDRMDQATALIAAAAHDVDHPGRSSQFLCNSNNPLAVLYNDLTVLESHH
AAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGSEVE
PRELVQSEEETSILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYFMQTDEEKQRHLPI
VMPMFDRATCSIPKSQIGFIEYIIQDMMEAWDSFIDMPQLITCMKINYSQWKKYDEQGVN
TLADIMAKQPPVGNNKPSNSK
>A0A7Z3YH22|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas veronii Hm21|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQANEHLYEVILAT
GDLSQDHSPESYQRFASMMAPLGRPIYWLPGNHDDSPLMTEYLHAAGISESKQLVGDHWQ
VILLDTQVRGKPHGMIGDHQLAALDRALRQYPERHALITLHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRVASEVWRLPVGQFVPDPNATGY
>D2U2B8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arsenophonus nasoniae|TrEMBL
MRILQITDTHLFANADDTLLGVNTFASFHAVIDAILVRNENVDLVVATGDLAQDQSAQAY
QHFAEGIKRLSAPCVWLPGNHDYQPAMVATLAKAGILPSKQLLINDNWQILMLDSQIQGA
VHGKLSKQQLLWMKSCFDAYTERSHLLMLHHHPLPSGCTWLDQHRLRNSHILADYLKQYQ
KIKAILCGHIHQEIDEYWQGVRMMATPSTCIQFKPHCTNFTLDTMTPGWRYLDLSINDAG
EDVLNTQVCRLDSDKFCPDLDSGGY
>A0A3A8FBG1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. WCHAc060007|TrEMBL
MPLINNNHQQKHESVFDWTIIQISDTHLMDQHELDFVSINPEQSFHEVMYHIRQEVPHID
AIIHTGDLAQVPVAETYARYLQFMTQLEIPHYQIPGNHDCTEIFPFHLQQDQAHILHYGA
WSTILLNSAVKDKVDGWISEAQLQQLHQLLSDHPQQHILIACHHHPFAMESAWIDQHKLK
NATHLMDVIAQHTNVKIVICGHVHQDSMNTWNNIQFLSTPSTSIQFKPHSQTFALDQVLP
GYRVIRLKNNGEFETEVHRVALSQPQINIEISGY
>A0A433SE50|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Saezia sanguinis|TrEMBL
MVPEPIKILLQLSDAHIVPEGQMLSGKVDTRSCLMQAIKQIKRMKLQPSAVVITGDLVDD
GELQSYAHLKDIISMLDMPVYVLPGNHDRRDHMLQAFPSLVQDPRMQSAGFIQYTAQVDE
LRLVVLDTSVPGKPHGELCDVRLDWLEDVLAQEPDCPTVVAMHHPPFKTGMAFMDGIRLL
KGVSRLEQIIASNRQVQRVVCGHVHRMCAHAFGGTVAITTPSVAHQMAFQFLPAEAPSFT
FESPGCLLHTWQASNVCVTSHLMALDDFAGPFSF
>A0A7L4ZCS5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kordia antarctica|TrEMBL
MMKNKYLYTLLICVLFFGCKHDTTKCVPCPECTKPHVEDVVVTTTTTSKFLALSDVHIDG
NLPQTRFEKKGKTDSSVTSDTLWQRTKAKIESVAKAENPKFMVYLGDLPGYDDSERRNNT
HLMLQNLRNLEVNVPILYLPGNNDSLEGDYYSFSNDSLNTVLNEDADASNPWPIINSKSS
TIQVKNLDDNQKQFGYYSVDLIDGTNTLKVIALNTVIFCAQGNHRYIDSDGVSQQKATQD
QMTWLETKLNSLGTNDRVIIMMHIPIGIDGFSGKQMWKNDLEFIDKSGNKQTLYNGFLDL
IAAHQTNIVGILNGHTHTDGLRRLYTSDAKSAMTTFSVSTPGIAVNHGNNPSFKTFTYDT
TTFDLLDFETYYASPTVHKTYKHSTHLKNTDFKFLDASSYTFQQSYKVSTPTQTIFNTLE
KQPKDSLVKFVNSTLGAKSNQNSKLKHPEAVNVYKN
>A0A1S9D0T1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chromatiales bacterium USCg_Taylor|TrEMBL
MKRTIVKSVETRYYEEREALFRGLKNLDRRSFLKLSAAAAAAALARGVEFNLHSFQPVQV
AHAATGEAGPVEFTFAYISDSHLYKRQLNDRFVRQLLRAVDDINHLAPQPDFVLYGGDLA
QLGQPLELELGAQILKNLKAPVKMMVGEHDWFLDMGEKWRTLFGEPTYSFDHKGVHFVVL
HSVMEDDFWSERGMTGMERMQTVAGLDNGIQSRFKVGTEQQVWLKNNLAAYSDDTPLIVF
SHSPLYKYYRPWNFWTDDAEEVQALLQRFKQVVVVHGHTHQILTHRIGNIHFHGMLSTAW
PWPYAPEGLPALTVQMNRADPFNPNDALGDGSVGVKAGGLVDKLYNLWNRNPIQVTSAYL
TSGGKSAVPLTPNLQSY
>A0A3R8ZDI8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLLEAGISPAKCVLAGD
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPARHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLVKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLAGTQFRPDTASEGY
>A0A6G9PXW7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salinivibrio costicola|TrEMBL
MQPCQIENANGDCIRLLQITDTHLFADEQGSLLGVNTLHSYHAVLDAISATQRTFDAIIA
TGDLSQDHSALSYRRFVDGIQRWQQPCFWLPGNHDFQPEMRSVLQSGSLSHCSQVLLGEH
WQMILLDSQVSGVPHGELSSEQLRLLDQHLSEYPQRHALVLLHHHPLEAGSTWLDQHKLV
NRERFWQIMAAHPQAKAVVCGHIHQALNVRHQGVQVMASPSTCIQFMPDSHDFALDNQNP
GWRWLDLYSDGRIESQVERVTGQQFRPDFDSSGY
>A0A6H1UJX6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ferrimonas lipolytica|TrEMBL
MSPLADDGSVLLAQVSDPHLFADRDNVFLGINPYDSFEAVVDELHGIDGLDSVLATGDIS
QDHTPGAYHQFAQMLATVNAPSYVLPGNHDLPHLMKALLVGPKVTCGRRIVVGDWQILML
DSTIKGKPAGHMSIDEQAWLLDMLKTHQMHTLVALHHNPIATGCTWLDQHSLDNGSEFLA
LLSRFDHVKGVIWGHVHQEMDLTYKNIRLMAVPSTSIQFLPNSHNFVLDTKQPGFRLLRL
HPDGSIETEVKRLNSGRFNPDGSATGY
>A0A553GWZ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas mangiferae|TrEMBL
MPSSPPHAPDSPVLLVQLSDSHLFAQADGRLLGMDTCDSLTLVIERVLQEQPTIDLILAT
GDLSQDGSVASYQRFRDLTAPIPAPARWIPGNHDDMPTMRAAFADSGVLDPVADVGAWRV
VMLDSSIVGAVPGYVDDEQLALLERALADAGERHVLICLHHHPVSIGCRWMEPIGLRNAD
AFFAVLDRFPRVRAVLWGHVHQAFDRERNGVRLLASPSTCVQFAPGSEQFQVGQEAPGYR
WLRLHADGTLETEVSRVTGIDFEIDYSVKGY
>A0A6H0KBP7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yokenella regensburgei|TrEMBL
MESLLNLPLAGGARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRASKRECDLIV
ATGDLAQDHSTAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQDAGISPAKRALIGD
NWQILLLDSQVFGVPHGELSEFQLEWLENKLAETPERYTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEMDVDWNGRRMMATPSTCVQFKPHCANFTLDTIG
PGWRWIELHADGTLTTEVCRLESAKFRPDTASEGY
>A0A0B1R8R4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea rodasii|TrEMBL
MDSLLTLPAANGADIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAITAQQHDYDLII
ATGDLAQDHTVEAYQHFVAGITRLPKPCVWLPGNHDFQPAMVDTLAEAGIASDKHVLLGE
HWQLVLLDSQVFGVPHGMLSEYQLEWLDIALRKHPERHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLQHFPRARNLVCGHIHQELDLDWHGRRVLASPSTCVQFKPHCTSFTIDNVA
PGWRWLTLKADGLLETEVNRLQSDMFRPDLDSEGY
>A0A644VM62|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MNSIRYFALFVFLCGLFATGLHAQTTLVSFTVSGKVSIPESAGIAGVVVSDGYQVTTTNA
EGEYTMQSTNFAKHIFISVPADCDIPHEGNIPRFYKSIKGTTSDITVNFTLTKKETDKAL
VLVVMADPQAQIPADMKRFTAEAIPDIETLKNNYPGDVAFIGMTAGDLLWDAPKMYPDYV
KAFEQLTFPFYQVIGNHDYDQTVKGNDYESSHNFESHFGPAYYSFNRGDCHFIALDNIIY
NTRPDYQEEISEEQLNWLQQDLKYVDKNKLIIISMHSPAYRRDGKKILNNTAELVKMLKG
YKVLIVSGHTHRMNKALVAKDMVDYTLSPTMGNSWAGDFNVDGCPNGYGVFEIRGNQLVN
QYYKSTGKSKDYQLKIYPAGSVPELPKSVVAHVWNYSEDWKVEVYEAGNYKGKMTNTTGY
DPDAYDFYLGAQKPDRKPKLEPAKTSNLFYYTPKNNKSEVKVVVTDCFGNTYVEYLNRIS
D
>A0A645ALB5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MIKLIHAADFHLDTPFRALPPDKAAERRSEQRELLSRFVGLAAEEKCDLVLLSGDLFDGE
RVYYETAQALARVLGQLGVPVFIAPGNHDPYAARSPYLAFRWPDNVHIFTSPIMESVALP
RLSAVVHGCAFTSKTRDDDPLSGFSVPGDGNIHLLCVHGDVGNKTGRYAPIDPAGIAATR
AHYAAFGHIHMASGLQRAGTVPWAYPGCPEGRGFDETGEKGVLCGTVSRESAALRFVPLC
KRRYEIKTVDVGGNPEEALKAALPTAPVDDICRILLTGESGPEGLNLAPLEAIAFPLFYT
VTLRDETRVRRDLWDRAEEDTLTGLFLRGMRLRLAACEEDKERSVLEDAVRFGLAALERG
EDIHP
>A0A2G6DNQ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurellales bacterium|TrEMBL
MSHFYQPLNSNGNIRILQITDTHLFAKQNDKLLGINTAQSFQAVIDAILETKFDYELILA
TGDLVQDYDEQGYHHFVNMVKPLKKKVFWLQGNHDQPQMGNVLASYPQISPLKHILIGEL
WQIIMLDSQVFGVPHGKLGSQQLKWLQKKLEQNPNRHTLIALHHNILPTHSAWLDQHSLR
NIHDLSNVLKPYKNIKAIIHGHIHQEMDKIWNGIRILSTPSTCIQFKPYSNNFALDFIPQ
GWRELTLLPDGTIDTQVKRLTTNQFIPDFNAEGY
>A0A0H6CTU4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cholerae|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFAAEDGSLLSVNTADSFAAVVAAIGEEQVEFDAILATG
DISQDHTPESYQRFVRGIQPLKKACYWLPGNHDYKPSMHSVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEYPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRIHLGARVMATPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A1H5JIB3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas palleroniana|TrEMBL
MPSVSTVNPDAPALLVQLSDSHLFAEASGTLLGMNTRESLQRVIELVRAQQPQIDLVLAT
GDLSQDGTLESYQQFRDMTRQIDAPARWIPGNHDEPHIMAHAAVHSDLLEPVLDIGHWRV
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPNRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDGERNGVRLLASPSTCIQFAPGSEDFEVSEQAPGYR
WLRLHADGRLETGVERVKNFVFTLDYGSNGY
>A0A7J0A183|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacteroides acidifaciens|TrEMBL
MKIIHISDTHGCHKRLTNLPEADVVVHSGDFTMNGSEPEALDFLNWLCDLPYAHKIFICG
NHDDCLYGANIDGLDPNVHYLCNSGVEIDGVRFYGVPMFMGDCITDRQAKNISKIPSDTD
VLITHSPAYGILDFDDDINYGDEQILSKVIEVKPRAHLFGHIHSQHGILTEHGITFSNGA
IMNADYTNLNQPNLINL
>A0A5F1F0B3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. E3659|TrEMBL
MESLLTLPLAGESRVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADSRFQPDTASEGY
>A0A4Q9VVQ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Azotobacter chroococcum|TrEMBL
MPSPSPSVADSSLLLVQLTDSHLFADMEARLLGMQTEDSLQRVIELVRREQPRIDLLVAS
GDISQDGSDESYARFRQLCAPIAAPLRWTPGNHDTREALSRASAGSECRQPIVDLGNWRI
VLLDSALPHAVPGFLEPSELALLERALAEAPERHHLICLHHHPVSIGCHWMESIGLRNAE
ALFAVLDRFPQVRALLWGHVHQEFDRMRRGVRLLASPSTCVQFTPGSEDFSVSDQAPGYR
WLRLQADGRLETGVSRLTDYRFQIDYGKGGY
>A0A0R2G3J7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lactiplantibacillus plantarum|TrEMBL
MRPLQVIQISDLHLTPRGQVPAHGQQYDPWGKLANIIDDIRRLPTMPDLIVFTGDLIHDG
SADDYQRLHAIIHTMEAEFDCHVRVILGNHDRRAAFYEGYLPADPGPYYASRMRIGNNDF
YFLDSKVSGYEAGWLAPQQLQWLGKHLRQAPTKRAFLFLHHPLDGPTMTNMHYAILQNTP
ALLSVLRGHNLGGVFSGHVHFVSSYLIGDNILNVVAGSAAYAIDCHDPHHHYVHEGSSYQ
IITIDRGQVGVTTRQLLHGKAVIDELTIPDTKFVGRAPQGYESR
>A0A7U4U782|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas hydrophila|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEMHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRIASQVWRLPVGQFVPDPNATGY
>A0A8G3HH76|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas aeruginosa|TrEMBL
MSRHSNTPATDASVLLVQLSDSHLFAEDGARLLGMDTAHSLEKVVERLAREQPRIDLILA
TGDVSQDGSLDSYTRFRRLSAPLDAPLRWFAGNHDEREPMQRATEGSDLLEQVVDVGNWR
VVLLDSSIPGAVPGYLEDDQLDLLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGY
RWLRLHDDGRLETGISRVDDVVFEVDYDTAGY
>A0A6J5E7L6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Burkholderia paludis|TrEMBL
MLLAQISDLHIKRPGQLAYRRVDTAAALARCIAKLNALVPRPDAVLVTGDLTDFGHDEEY
GNLRGLLAALEIPYYLMIGNHDDRAGLRRAFAERAELHDGEFVQYALDLGAVRVLALDSQ
VPGASHGDLCDTRLAWLAAQLDAARDRPVIVALHHPPFVSGIGHMDALRLAPAAAAKLDA
LLRGHPNVERVLCGHVHRTMFTRFGGTLAAAVPSPAHQVAFDLRADAPSAFRLEPPAFAV
HRYAPDTGMTSHHVYVDEGAGPYPFYEPTGELVD
>A0A6G6SX67|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteus terrae subsp. cibarius|TrEMBL
MESQLELSVKQKNTVRILQITDTHLFANVEDTLLGINTYRSYHAVLNAIREQGLDVDLIV
ATGDLVQDQTFEAYQHFADGIATLVPPCVWLPGNHDYQPAMIDALNQAGILSAKQVLIGD
NWQMLLLDSQIQGVPHGELSDCQLDWLTRCLESQKHRDTIILLHHHPMPSGCTWLDQHSL
RNSQELAERLKDHSQVKMMLCGHIHQEMDEMWNGIRLLATPSTCIQFRPHCTNFTLDTVS
PGWRYLEMSLSSDEKGKIDTQVYRLEGTEFCPDLDADGY
>A0A1E7Z123|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Erwinia dacicola|TrEMBL
MDSLLKLPVASGSRFRILQITDTHLFAGKHETLLGVNTWASYDAVLEGIAAGQRHYDLIV
ATGDLAQDHSVKAYQHFAEGIAGLPAPCVWLPGNHDFQPAMFSALTESSIADEKQVLVGD
HWQIVLLDSQVFGVPHGELSDYQLEWLEHALAAEPQRHTLVLLHHHPLPSGCSWLDQHSL
RNPHMLDAVLQRYPLAKILLCGHIHQELDLDWHGRRVLASPSTCIQFKPHCTNFTIDAEA
PGWRWLDLYDDGRLETDVQRLATRKFNPDLDSEGY
>A0A5S9PGX5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Zhongshania aliphaticivorans|TrEMBL
MVQISDCHLGAHQGDSLLGMDTDHSLEAVLATIASECPVIDLLIVSGDIAAHGDAASYQR
LLARLDGVASQMVWLPGNHDDADLMLSVAGEKLMPSELELGGWRLGFLNSAVKNEVGGLL
AADQLEVLKGIVACEQPSLVFLHHHLRALGCAWLDEQRVANADDVFAIADAGPQLKAFVS
GHVHQHSEMVFQNKGLLTTPSTCIQFAPDSDSFALDDSNPGYRIFWLAENGQFQTRVSRV
KGVTFTVDNLASGYE
>A0A6P4LDW2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila bipectinata|TrEMBL
MGCSPSTLPAPSSTSAAAGGQPTSGQGSLPPLDASEKDGSRLFCIKLRRSRLRRCSCGGV
TLQTPNDGNGSTAGSGAGDNLCGQVLLNPLQTKNEADYEKLSTGKKDSIVTVAALGNFTH
SVVRRATGSTGTSGTSSSGGGNSRPGHRKSSLAFALTPEDEPMDVYQRNLMDLKYPTVLP
PNPQLKALLVFYKADSICEAVSAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIII
DARSSKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTN
LAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLN
MRLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMHVRVVPVACIGS
APTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLT
SLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDL
IGALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKANPIIMELLDESLSWDFDIFK
LEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADV
MQATGAFITQLTNRDMMVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDSLAVLYNDL
TVLENHHAAITFKLTLGDDKINIFKNLDKEQYKSARSTIIDMILATEMTRHFEHLAKFVS
VFGGDESREPHAQTEEETSILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYFMQTDEE
KQRHMPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKK
YDEQGINTLADIMAKQPPVGKLANSK
>A0A156ISB0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLTGAKFRPDTASEGY
>A0A2J7QT83|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cryptotermes secundus|TrEMBL
MWGWNIFSVLSNSLGLCFRHGRRGTLDLENGNSSQKNQQTTGTPGGFSITNQDCTTKVLL
AFGKEDFQSDAFWLACEKLGYECNLARTRDSVLEAFQTKSHEIVIIDTRNPKVIDGESLC
RALRALKTSQYTVVVGVVRKGTSEKEDSSIEPMLNMGFNRVIMETSGLVQCMNELLQLYL
SDVQPRLQLATAQAMHIALDKCSDVVHITDQNLNIQYMNRSSERFLGFSMKDVAGKSLLE
TNSVDNKELMVQQLQRGREWEGLISWRRKMGDSVVLSGRVIPVCSPGRSPTHYIFIHESQ
HMMLDKRMSGTLVKNPELPKGSNNRKGSADMKSISSDGLRRQSIAKLHNLSIEAPITKVI
ALITSVQDNANIEDIQTLDKVVDILRTTELYSPQLKDDKGKAGDPVTNDLIGALLSSGPS
VTPIARRSSSDSGSVSKIGLSRSTFKTANMSHQMKELLDTSLLWDFDIFRLEELSVKRPL
VYLGMNLMDHFDVCSSLGCEENVLHNWLVVIEENYNAKNTYHTSTHAADVMQATAGFLER
ERLKQILDPLDEAVCLIAAAAHDVDHPGKSSAFLCNSNHELSILYNDLCVLESHHSALAF
KLTISDDRVNIFKSLERDVYKAVRQNVIDMILATEMTKHFEHLAKFVNVFSIKKEDDSPD
GGRSSPDIGILTAPENITLIKRMLIKCADVSNPTRPLRMCVEWAVRIAEEYFNQTDEEKA
NNLPVVMPLFDRATCSIPKSQIGFMDFIINDMFETWEAFIEMPELLQNMQHNYKFWKEKE
KCGIHRIQDVIMMQHTVKTSGKTD
>A0A5I2DYC7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Uganda|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A7D6VHW6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter freundii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQCVLDAIHAESTDFDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPSGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIS
PGWRTLELFADGSLHTQVCRLPGIRFHPDTASEGY
>A0A5X5WMC0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Corvallis|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A3G6YLC2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter pittii|TrEMBL
MTFQVSTLSQKDHVIIQITDTHLLEYPHLEFVGMNPEESFHAIMQQILNKHPEIDAIIHT
GDLAQAPTPITYKRYIQYMQTLGLPFFQTLGNHDNVDHFPLHKENHQEPVVICLGNWRVI
LLNSAVKGHIDGHLSAEQLENLTNLLEEYADNPILLACHHHPFAMKSKWIDHHKLQNSNA
LLTTLAPFKNVKALVCGHVHQDSINTWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLKNDGSFETEVFRLENFQGHINTDISGY
>A0A264VVY7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia rettgeri|TrEMBL
MDSQLEVTAKNSKVVRILQVTDTHLFANTENTLLGVNTYRSYQAVLDAISEENLPIDLIV
ATGDLVQDQSPQAYQHFADGIARIPAPCVWLPGNHDYPPAMVKTLRIAGISSAKQVLIGD
EWQILMLDSQLQDVPHGELSEQQLEWMKASLDAEPERTTLIMLHHHPLASGCTWLDQHSL
RNSHILADYLKSYSNVKAMLCGHIHQEMDENWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELSINEQGQRHITTRVHRLDTREFSPDLDSDGY
>A0A730Z508|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella typhimurium|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGLASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A7R9N1N7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Methanoperedenaceae archaeon GB37|TrEMBL
MAKVRYMKKYLFNKFISCIVILTLIVSVGIKLYSVFTFPEIEDWNYKQIKKIDETHNSYS
FAVFGDNRNSITTFNNLIHKLNKDSIIFAIDVGDLVEDGEKEKFRFFINQIKKVNKPFLT
VIGNHELRENGRANYYQMFGRFYYSFTVGKSYFIILDDANEKRLDLWQLDWLIKELKKSQ
SYKYRFVFIHVPLYDPRKGGDKKGHSLKDVTFARYLNKLFDKYHVSMLFCSHIHGYYKGY
WQNTPFIITGGAGAKLAGTDPSHYFYHYIKVNISEQGVQYEVVRLNTPDFELIDRLLHDT
GMFIYAFIAIHFDIIIIIGCIYILILLYFKQDKIKIMYHA
>A0A1W5DR54|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia proteamaculans|TrEMBL
MESLFKPTVASGARVRILQITDTHLFAGENETLLGINTYRSYHAVLDAILAQQRDFDLVV
ATGDLAQDHSLAAYRHFAEGIARLPAPCVWLPGNHDFQPAMVDALADAGIAPSKQVLVGD
HWQVLLLDSQVFGVPHGELSEYQLEWMERCLQAYPDRYTLMLLHHHPLPSGCTWLDQHSL
RNPHTLGAVLLRYPKVNTLLCGHIHQELDLEWQGRRLLASPSTCVQFKPHCTNFTIDEVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A8B9LBR1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Astyanax mexicanus|TrEMBL
MDRTYAVDTGHRPGLKKSRMSWPSSFQGFRRFDVDNGTSSGRSPLDPMTSPSSGLILQAN
FVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFA
ALTNLQQDRTSNK
>A0A5P1B686|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter junii|TrEMBL
MTFQVSTLSQKDFVMIQITDTHLLEYPHLEFVGMQPEQSFHAVINLMRQTHPEIDLIVHT
GDLAQNPTPLTYHRYLEYMHSLSIPFFQTPGNHDDVNHFPFHEQDKTAPTVVELGNWCVI
LLNSAQPNRIDGKIADAQLQQLPKLLTQLHDRYVIIACHHHPFAMQSAWIDQHKLKNSSD
LLETIQLFSNVKAIICGHVHQDSITSWQGVEFLSTPSTCIQFKPKSEKFALDEEHPGYRY
IRLKANGEIETQVHRLSNSQRLSSSEVLGYD
>A0A6G7CFI9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio ziniensis|TrEMBL
MNVSLSIDNPDSIKLVQITDTHLFAPDDGCLLSVNTADSFRAVVKEICAKQIQYDAILAT
GDISQDHSAESYQRFSDGIQLLKKDCFWLPGNHDYKPNMGGVLPSPQIRTAEHVLLGEHW
QMVLLDSQVVGVPHGRLSDHQLVLLEEKLAQHPERYTLVLLHHHPLLVGSAWLDQHTLKD
SESFWDVVKCHTNVKAVLCGHVHQNMDKEHLGVRVMATPSTCVQFKPNSNEFALDKTSPG
WRELELCSDGSVISAVKRLPNGVFQPDFDASGY
>A0A0H2MXY1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. VPAP30|TrEMBL
MKVTSSSSDSDSIKLLQITDTHLFEPADGSLLSVNTLDSFHAVVSAIIEENQPFDSIIST
GDISQDHTAESYQRFEQGIAPLEKTCFWLPGNHDFKPSMTSVLPSTQIKQIDHVLLGEQW
QMVLLDSQVVGVPHGRLSDHQLALLEEKLTQYPERHTLVLLHHHPLLVGSRWLDQHALKD
ANHFWDVVEKHQNVKAVLCGHVHQDMNVLYNGVRVMATPSTCVQFKPNSDDFALDTLSPG
WRELELHADGQLTTQVKRLPYGCFQPDFNSAGY
>A0A7Y4FR72|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. T3Y01|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGER
WQMIMLDSQVVGVPHGRLSDQQLDLLEQKLAEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHSNVKAVLCGHVHQDMNREHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPHGQFLPDFKAAGY
>A0A7J8BMB1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Molossus molossus|TrEMBL
MGCTPSTHIFESRAVCPGCEEAEAAPGGPRLPASSGTTSSAEDRGAVRGEPQARGGPSEK
VTVTNVQIGPMRFHPDQLQVLLVFTKEDNQCNGFCKACEKAGFKCTVTKESQAVLACFLA
THHDIIIIDHRNPRNLDAEALCRSIRSSKFSENTVIIGVVRRRDKEDSSVMPLIAAGFTR
RYVENPNLMACYNELLQLEFGEVRSQLKLRACNPVFTAVEKSQEAVEIISDTNLIQYANP
AFESTMGYASGELIGKDLGEVPIHEKKAELLDTINSCIKLGKEWHGIYYAKNGDNVQQSV
KIIPVIGQGGKIRHYVSIIRVCNDKAEKITECVQCDTHTDNQSGKHKDNRKSSLDVRTVS
SRTSEVSSQRRHSSMARIHSMTIEAPINKVINIINAAQENGPVSVTEALDRVLEILRTSE
LYSPQFGAKDDDPHGSDLVGGLMSDGLRRLSGNEHALSTKNLQVPSNAATPISLHDVPLQ
IAQAMEHEDYWDFDIFELEAATQKRPLIYLGLKIFARFGICEFLNCSETTLRSWLQIIEA
HYHSSNPYHNSTHAADVLHATAYFLCRERVKQTLDSVDEAAALIAATIHDVDHPGRTSAF
LCNAGSELAILYNDIAVLESHHAALAFQLTTGDDKCNIFKHMARNDYWTLRHTIIDMVLA
TEMTKHFEHVNKFINSVNKPLAELEENMVTDKDQAAINTVLRTPENRTLIKRMLIKCADV
SNPCRPLEQCIEWAARISEEYFSQTEEEKQRDLPVVMPAFDRKTCSIPKAQISFMDYFIT
GMFDAWDAFVNLPELLQHLDNNFKYWEGLDKMKLRSLRPPPPPEPK
>A0A5S9N7N5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|BD1-7 clade bacterium|TrEMBL
MPLKVLQISDCHLPDVAGDTLLGLDTEMTLKRVCEHAFTHHPTPDLIALTGDITNGKEDT
AYHMLREHLPTDVPLAWLPGNHDNNRVMQPVVSDEFLPSLTMGNWCLTFLDSSIDGAVPG
LLEDGEVQRMDNVLRGAPDKHHLIFMHHHLKPAGCAWLDTQVVKNAPHVLGLMAGFRQLK
AVAHGHVHQAFEQKHAHFDILACPSTCFQFKPLSDNFALDDKMPGYRYFELFDDGSYISR
VERIEYIELPIDHKAGGY
>A0A8G4ADP6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas aeruginosa|TrEMBL
MSRHSNTPATDASVLLVQLSDSHLFAEDGARLLGMDTAHSLEKVVERVAREQPRIDLILA
TGDVSQDGSLDSYTRFRRLSAPLDAPLRWFAGNHDEREPMQRATEGSDLLEQVVDVGNWR
VVLLDSSIPGAVPGYLEEDQLELLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGY
RWLRLHDDGRLETGISRVDDVVFEVGYDTAGY
>A0A318FWN0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella oxytoca|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQILLMDSQVFGVPHGELSDFQLEWLEHKLAEVPERYTLLLLHHHPVPSGCSWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHSANFMLDIVS
PGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A6S5DIE5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas veronii|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHPYEVILAT
GDLSQDHSPESYQRFASMMAPLGRPIYWLPGNHDDSPLMTEQLHAAGISESKLLVGDHWQ
VILLDTQVRGKPHGMIGDHQLAALDRALRQYPDRHALITLHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRVTSEVWRLPVGQFVPDPNATGY
>A0A0B8NRX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio ishigakensis|TrEMBL
MEPRIVETGESVQLVQITDTHLFEDSEGTLLSVNTEHSFHAVVEDVISKELAFDAIIATG
DISQDHTAASYEKFVEGIKPLVKPCFWLPGNHDYKPSMGSVLPSAQIQACNHFLAGEKWQ
VILLDSQVTGLPHGYLEQEQLAYLDDMLAEYPERHSLVLLHHNPLPIGSAWLDQHKLQKA
VEFWQVLDRHKNVSAVLCGHVHQEFQTEHHGVQVLATPSTCIQFKANNDEFALDNLSPGW
RHLSLHSDGSIESKVYRLPDGSFVPDFEAEGY
>A0A7X1KF36|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. MSSRFD41|TrEMBL
MPSVPASPADDSVLLVQLSDSHLFAETHGTLLGMNTADSLQRVIDLVLAQQPQVDLVLAT
GDLSQDGSLQSYQRFHQLSAQIPAPARWLPGNHDEPGVMRLAAQGSELLQPVVDIGNWRI
ILLDSSVPGSVPGFLQDEQLQLLVRSLDEAPGRHHLICLHHHPVSIDCAWMEPIGLRNAE
ALFEVIEGRPQVRALLWGHVHQEIDRWRDDLRLLASPSTCIQFEPRSDDFKVEERAPGYR
WLRLLADGRLETGVQRVEGYAFTVDYGSDGY
>A0A518XFR7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea dispersa|TrEMBL
MDSLLTLPAANGSAIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIAAQQREFDLII
ATGDLAQDHSVEAYQHFVAGIARLPKPCVWLPGNHDFQPAMVDTLAQAGIAADKHVLLGE
HWQLVLLDSQVSGVPHGMLSDYQLEWLERTLRQFPQRHTLVLLHHHPLASGCTWLDQHSL
RNPHQLAAVLQHFPLARHLVCGHIHQELDLDWQGRRVLASPSTCVQFKPHCTNFTIDTVA
PGWRWLTLQADGALETEVNRLQSEMFRPDLDAEGY
>A0A4V3SSD6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rodentibacter pneumotropicus|TrEMBL
MKNTFVYRAEKPVVKLLQITDPHLFKDEKNELLGVNTQASFAQVLKEIQQEKREFDAILA
TGDLVQDSSDEGYQRFVNMVKPFGLPVFWIPGNHDFQPKMVENLNQSPMEKAKHILLGEY
WQVLLLDSQVYGVPHGELSQYQLDLLKTTLEKYPEYHTLIVFHHHVLPTNSAWLDQHNLR
NSHDLFDVLSLFKNVKGILYGHIHQQVDSLWQGYQVMATPSTCIQFKADSQHFALDKAQP
GWREIELHSDGTIVTAVKRIRQAVFLPNMQEEGY
>A0A377JFE7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus parainfluenzae|TrEMBL
MNNTFECEPASEIVKLLQITDPHLFKDTSKDLLGINTHESFSQVLKEIQAESFNYDVVLA
TGDLVQDSSEEGYLRFVEMVKPLNKSVFWLPGNHDFQPKMVEHLSQSPINASKHLLLGKH
WQVILLDSQVSGVPHGELSAYQLDWLKMKLAENPARHSLVVLHHHLLPTNSAWLDQHNLR
NAHEFSEILSQFNNVKGILYGHIHQEVDGYWQGYQTMATPATCIQFKPDSNHFALDTLQP
GWREIELYPDGRIETRVKRIKQKTFLPNMEEEGY
>A0A672URN3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Strigops habroptila|TrEMBL
MRSKCPSEGGQPAYFQACSVHSFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRE
SFLYRSDSDYDLSPKTMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGT
SNK
>A0A2R8BU51|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Palleronia abyssalis|TrEMBL
MIRILHLSDLHFGRDRPELEGPLVHTVNRLAPDLVAISGDFTQRARRGQFERARAFVDQL
APETLSVPGNHDTPLDNLFLRFLKPFHRYKTFIDRNLEPSLETDEMVVTGVNTVNRFSWQ
RGRLSRRTIRKVARSFQTAGDRLRVVVLHHPLEHGPEVDKRLMRGANAALTALNDAGADV
VLSGHLHNTVTRPFAIAPGCLFVQAGTGLSNRLRGEPNTFNLLTASREKIEIDTFSAGDD
AVFDVRGRRTFTRSAEAAWVAD
>A0A803YK27|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Meleagris gallopavo|TrEMBL
MSDLAWHFYLFFRTDTIVSYMGRVQVCTIGKVRNENQQQCRRPSFITLRHGDDLIVTPFA
QVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITGSYISMA
>A0A329WZQ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus bodei|TrEMBL
MESQFELPVVEGTTAKILQITDTHLFASKEDTLLGINTYRSYQAVLDAILKQNADIGLIV
ATGDLVQDQSLEAYRHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGK
HWQLLMLDSQVQGVPHGELSEYQLEWMKKCLDRYPERYAVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQSYSRVKAMLCGHIHQEMDLDWNGIRMMATPSTCLQFKPHCTNFMLDTVA
PGWRYLELSVADNGEFGLTTQVYRLASNEFCPDLDSDGY
>A0A6C7D5D0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae serovar 56:b:[1,5]|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGD
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A091S6Y9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nestor notabilis|TrEMBL
FDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSS
LPSEQHGDDLIVTPFAQVLASLRSVRNNFTLL
>E1SEB7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea vagans (strain C9-1)|TrEMBL
MDSLLTLPAANGSEIRILQITDTHLFAGKHESLLGVNTWSSYDAVLDAIIAQQRDYDLII
ATGDLAQDHSVEAYQHFAEGISRLPRPCVWLPGNHDFQPAMVDTLAAAHINAHKQVLVGE
QWQIVLLDSQVYGVPHGMLSDYQLEWLDNALSRFPQRHTLVLLHHHPLASGCTWLDQHSL
RNSHQLDAVLQRYPLARTLVCGHIHQELDLEWHGRRVLATPSTCVQFKPHCTSFTIDTVA
PGWRWFTLHPDGGLETEVNRLDTDAFRPDLDSEGY
>A0A6P8WJB9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila albomicans|TrEMBL
MGCSTSALPNSASTTAAPGVGVGVGIGGNGGGPNAPLPPLDANEKDGSLLFCIKLRRSRM
RRCSCGAVTLQQQNGDGSTGSATCGDNIMCNQVLLNPQQTKNESDYEKLSTGKKDSIVTV
AALGNFTHSVVRRATGTGSTGTSGTSSSGGGRPGHRKSSLALALTPEDEPMDVYTRNLMD
LKYPTVLPPNPQLKALLVFHKSDSICEVVTLACQRHQLDVTLVKSKEEALDTLQKSYATA
QCYHLIIIDARSTKGLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDALIALLDAGVN
RCIAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYAN
RATERLLNMRLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMHVRV
VPVACIGSAPTHLIFNFDIPGGGMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLR
RTSLAKLTSLPLEAPITKENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLI
GALLTGPSVYSSRRSSNDSIIRTGNSTRTAIVPAKMKANPIVMELLEESLSWDFDIFKLE
EITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADVMQ
ATGAFITQLTNREMVMDRMDEATALIAAAAHDVDHPGRSSAFLSNSNNPLAILYNDLTVL
ENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFG
SEVEPRELVQSEEETSILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYFMQTDEEKQR
HLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWDSFIDMPQLITCMQINYSQWKKYDE
QGVNTLADIMAKQPPVGNKPSNSK
>A0A857I5U3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter gyllenbergii|TrEMBL
MTFQVSSLSQQDFVMIQITDTHLLEYPHLEFVGMQPEQSFHAVIDLMRQQHPHIDLIVHT
GDLAQSPTPLTYKRYVQHMQSLGIPFFHTPGNHDDATHFPFHEVDHTQPTVIELGQWCII
LLNSAQPERIDGKIAEVQLQQLTQLLTQLHDRHVIIACHHHPFAMQSAWIDQHKLKNSSD
LLETIQPFSNVKAIVCGHVHQDSINTWQGIEFLSTPSTCIQFKPKSDKFALDEEHPGYRF
IRLKANGELETQVYRLPTSQRMNSSEVLGYD
>A0A385ZVU6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces griseorubiginosus|TrEMBL
MSRTRSVASTQPAVHRRTVLAAAGAAAASAGIGYALRPTDSQAATATTGAAEAPVARTVH
QAAAPAEAPLAPYTRGTTVASIAAPRTSSGYRRLGDGPGWSRKVRSDLAAPKSGRAGRRT
SLAAFVQFTDLHLMDSQHPARLEYLRSTDVHAWRPQEALTVPGAISLVERVNALRGGPVT
GAPLQFAMTTGDNTDNNSHTELDWFLTVMSGGRITPNSGDPRHYEGVQNSGLKQYWQPDS
TTRDNDKRLGFPHLKGYLAAAVREVNSPGLNIPWYSTVGNHDSLPLGCFGHGDSWLAEYA
VGGKKLMSLPASEAKKLQDTIRKASDPQGHHFRDLLKAHARSMRSVTPDERRAPYTARDY
LKAHLDPAYRGVGPVGHGYSTANLDAGTQYYSFRIADDVIGISLDTTDPGGHYQGSIGAA
QLRWLDRTLRENKDSFAVVFSHHTSDSMDNLRRDPAHPGERRYGGADVVALLASHSNVLA
WVNGHIHRNVITAHAAPDGRSFWEISTASHIDFPHLARIIELVDNKDGTISVFTTLVESA
APHRTDFTDLSQTGLAALYRELAYNAPGSSNKLGGGAVDRNTELVLKKG
>A0A2Z6V1F4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcystis aeruginosa Sj|TrEMBL
MNFRFAILSDPHIALPTTILNHSNRFHLVEVSIPALKIVLDHLITLNLDFLLIAGDLTQD
GEPENHRWLADCLATLPFPVYVVPGNHDVLSLTATENQIGLADFPFYYQQFGYSDPEQIY
YQKEILPRVQLIGLNSNQFDEQGKQIGSLDAEQLHWLKQTLPALKNDLVMVMIHHNVIEH
LPGQSNHELGKRYMLANAVELLDILQENGVKLLITGHLHVQDLAFARGIYEITTGSLVSY
PHPYRVLEYCENTVELAIESFHLQNIPGWENLPAISRQWLGDRSYPFMMRLLTCHPLNLP
VSLAEELAPKLRNFWADVAQGDTIFDFSDFPPLVRRYFYAFSAIDPLGNPHFIDNQAVIS
FKHQFSYQRSDLLVELRE
>A0A8B6GJ69|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mytilus galloprovincialis|TrEMBL
MLTVPTIQEPKRRHSWICFDVENGTGPGRPTLEGSSPSSSRLVLQNLPQRRESFLYRSDS
DYDLSPKSVSRHSSMQSEIHADDLIVTPFAQILASLRSVRNNYISLTNVQAPRER
>A0A1V3LAI8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rodentibacter ratti|TrEMBL
MKNTFVYRTEKPMVKLLQITDPHLFKDEKNELLGVNTQASFAQVLKEIQQENTEFDAILA
TGDLVQDSSDEGYQRFVNMVKPFGLPVFWIPGNHDFQPKMVENLNQPPMEKAKHILLGKY
WQVLLLDSQVYGVPHGELSQYQLDLLRTTLEQYPERHTLIVFHHHVLPTNSAWLDQHNLR
NSHDLFDVLSDFKNVKGILYGHIHQQVDSFWQGYQVMATPSTCIQFKADSQHFALDEVQP
GWREIELHSDGSIVTTVKRIRQAVFLPNMQEEGY
>A0A661GWN2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MHTPTKHRPIHLDHPGGTVQLVQLTDCHLGHAPGSKLLGMDTDHSLQAVIDLVKRERKQT
DLVLGTGDLSDHGANAAYGRLYQYFSQVCTSSFWLPGNHDSWHDMAADSGPNCQLSNEVR
IANWQILMLDSQIPGEIGGELGVDQLALLDDCLQRADAEGLHTLICLHHHPIAIGSDWLD
QQMVADAEEFFTVVGRHSSVRAILWGHIHQQIDSERDGIALLATPSTCVQFAPGLAKFKD
DDLPPGYRWLDLEPDGTINTAVSRVQGVSFTVELDSGGYL
>A0A6M8UD28|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwiniaceae bacterium PD-1|TrEMBL
MDSLLKLPVASGTHFRILQITDTHLFAGKNETLLGVNTWASYQAVLSAIETERQDYDLII
ATGDLAQDHSVEAYQHFAEGIARLPAPCVWLPGNHDFQPAMFETLGNTSIADQKCVFLGE
HWQLVLLDSQVFGVPHGMLSDYQLEWLESVLAAEPERHTLVLLHHHPLASGCSWLDQHSL
RNPHALDAILQHYPLAKTLICGHIHQELDLDWNGRRLLATPSTCVQFKPHCTNFTIDSVP
PGWRWFDLFDDGRVETTVCRLKTAAFSPDLDSEGY
>A0A3M1KLX7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MTDRNAVLSIVQITDSHLRREADGQLLGMNTRQSLTEVLKLVRSRARHPDMVLASGDIAQ
DHSREAYEAFADLLDGLEDSLYWFAGNHDDPKVMDAALQPVCGGRGAPCVVDCDPWRIIL
LDSSVHGEVHGELGAGQLAFLGEALESSGDRHVMISFHHHPIDVGSTWLDAIGLKDRDAF
FDLVDDFANVRLILWGHIHQEWDSMRNGVRLLATPSTCVQFKPGSEDFAVGDNAPGFRTL
SLYDDGTIETEVIRADHIAFEVDYDSKGY
>A0A3L7LVB6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sodalis-like symbiont of Bactericera trigonica|TrEMBL
MESLLKLPVARGANIRILQITDTHLFAGEDETLLGVNTFRSYSAVLKAVQAEQRHFDLVV
ATGDLAQDHSPQAYRHFAAGIARLPAPCVWLPGNHDFQPAMVDVLAECGISCAKQVLIGE
EWQLLLLDSQVYGVPHGELSDYQLEWLARELASQPERHTLLLLHHHPFPSCCIWLDQHSL
RNAHMLAEVLKPHQRVKTLLCGHIHQELDVDWLGRRVLATPSTCVQFKPHCTNFTIDTLG
PGWRYLDLLPGGLLQTEVHRLVGAEHQPDTDYEGY
>A0A135ZIM3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium sanguinicancri|TrEMBL
MQTYTLPQQGPDKVVLLQITDTHLFNDISGSLLGIETKKSFHAVLDAVDDAARPFDAIIA
TGDISQDHSENSYQRFADGISRWTQPCFWLPGNHDYQPTMRSVLPSPQIKPCEQVLAGEY
WQVILLDSQVPGVPHGALSSAQLEMLDNALRMHPERHALVLLHHHPLEVGSSWLDQHQLH
NNEALWYVLDQHPQVKAVLCGHIHQELDRMYRNVRVLATPSTCIQFLPDSNDFALDQVNP
GWRYLELYANGDIRTEVSRVQGLQFAPQFDEAGY
>A0A1E4VSA4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sp. DNP9|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHPYEVILAT
GDLSQDHSPESYQRFASMMAPLGRPIYWLPGNHDDSPLMTEQLHAAGISESKQLVGDHWQ
VILLDTQVRGKPHGMIGDHQLEALDRALRQYPDRHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRIASQVWRLPVGQFVPDPNATGY
>G9Z2Z3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yokenella regensburgei ATCC 43003|TrEMBL
MESLLNLPLAGGARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRASKRECDLIV
ATGDLAQDHSTAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQDAGISPAKRALIGD
NWQILLLDSQVFGVPHGELSEFQLEWLENKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLATFPRVKNLLCGHIHQEMDVDWNGRRMMATPSTCVQFKPHCANFPLDTIG
PGWRWIELHADGTLTTEVCRLESAKFRPDTASEGY
>A0A829DJG1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli 2875150|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A165KM50|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella baltica|TrEMBL
MLKEAVSYSIAEGESVRIVQVTDPHLFADPEAQLLGVNTSKSFAAVLNTIRAVDYPAHLM
LATGDLSQDYSAESYQQFVKAVTPIGLPCHYLPGNHDDPRIMYLHMQGEQIFGQQRILAG
NWQILMLDSTVRGKPGGNMAETQFELIDKAIAAHPECHTLLVMHHNPIVVNCTWLDQHCM
DNGAEFIARVAKYPQVKGLLWGHVHQCIDIHHNGPHGSMQLMATPSTCIQFKPLSPYFAL
DSVQPGYRLLELRADGSINTKVYRVPGNHFSPDNNSSGY
>A0A1R3FCW0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. 10N.222.47.A9|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIKPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDD
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPDRNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAILCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGSVTTQVRRLPNGQFSPDFDAGGY
>A0A1B9P2R0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aliivibrio logei|TrEMBL
MLSETLLNKKNGPIRLLQITDTHLFALPEGALLGVPTLKSFQSVVEQVQQQSPHFDAILA
TGDISQDHTVQSYQHFVEGIEPLKKPCYWLPGNHDYKPSMGGVLPSPQIKDCEHLLIGEH
WQVVILDSQVVGVPHGALSTEQLQLLDSALSQHSERHSLILLHHHPLPAGSAWLDQHQLK
DNEVFWEVLAKHRNVSGILCGHIHQEMDCIVNNIRLMATPSTCVQFLPDSNDFALDSKAP
GWRTLDLLPNGEIVTQVYRLEHCDFSADADAGGY
>A0A221DVA3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia marcescens|TrEMBL
MESLFKLPVASGAAVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAIQAQRRDVDLIV
ATGDLAQDHSQEAYRHFAAGIAQLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKLVLLGD
SWQVLMLDSQVFGVPHGELSEYQLEWMERCLQAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAILLRYPKVNTVVCGHIHQDLDLEWQGRRLLATPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A1A8CI55|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothobranchius kadleci|TrEMBL
MSSNELSVEMDSCIRTFKEHMHLELEPPKMPGVMGGKRGATSPKLSPRSSPRLFRKLMVN
KSIRQRRRFTVAHTCFDVENGPSASCSPLDPQASPGSGLVLHTNFPGHNQRRESFLYRSD
SDYELSPKSMSRNSSIASELHGDDLIVTPFAQVLASLRSVRNNFTILTNVQCPSSKRSPA
ATTQPPITKVCLPDEAYQKLAMETMEELD
>A0A2N5E335|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chimaeribacter californicus|TrEMBL
MESLFTLPVAGDARVRILQITDTHLFAGEHETLLGVNTLRSYHAVLDAIAAQQRPVDIIA
ATGDLAQDHSLAAYRHFAAGITRFPAPCLWLPGNHDFQPAMVDALAGAGIAPSKHALLGD
HWQMILLDTQVFGVPHGELSDYQLAWLARCLSAYPERYTLLMLHHHPLPSGCNWLDQHSL
RNAHELAALLVHYPKVNTLLCGHIHQEMDEPWHGRRLLATPSTCVQFKPHCTSFTIDSAA
PGWRYLDLYPDGRLETEVHRLDTHEFCPDMDSDGY
>D3V2H3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus bovienii (strain SS-2004)|TrEMBL
MESLLKVPVAEGATARILQITDTHLFASKGDSLLGINTYRSYHAVLDAILEQSIDIDLIV
ATGDLVQDQTIGAYQNFAEGIARLPAPCVWLPGNHDYQPAMVDVLAAAGISPSKQVLIGQ
HWQLVMLDSQVQGVPHGELTDYQLEWLQKCLDKHNDRNTIVMLHHHPVPSGCTWLDQHSL
RNAPALAESLKDKLQVKAILCGHIHQELDRMWNGIRVMATPSTCMQFKPHCTNFMLDTVA
PGWRYLELSVADNREAKLQTQVHRLKSNEFCPDLASDGY
>A0A2S7XG98|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aliivibrio sifiae|TrEMBL
MLSETLLKNENGPIRLLQITDTHLFAPIEGALLGVPTLYSFQSVVEQVQQRTSDFSAILA
TGDISQDHTVESYQHFVNGIKPLEKPCYWLPGNHDYKPSMGGVFPSPQIRASEHLLIGKH
WQLIILDSQVVGVPHGALSIEQLELLDKALTQYRTRYSLILLHHHPLPAGSAWLDQHQLK
DNEHFWNVISKHSNVKGILCGHIHQELDRMINGVRLLATPSTCVQFLPDSDDFALDSQPP
GWRTLDLLPNGDIDTEVHRLEHCNFSADVEAGGY
>A0A7Y3ZYP8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio pectenicida|TrEMBL
MKVTSSSVDGSIKLLQITDTHLFEANDGSLLSVNTADSFDAVVNAIVKQNSNYEAILATG
DISQDHSAASYQRFEKGVSKLNKVCFWLPGNHDYRPSMDSVLSSSRIQYVEHLLLGEHWQ
MIVLDSQVEGVPHGRLSDEQLALLVDKLSCYSQRHTLILLHHHPLLIGSAWLDQHALKDS
ERFWDIVESHSNVKAVLCGHVHQDVDTYRNRVRVMATPSTCVQFKPRSDDFAVDNHSPGW
RELLLCPSGNLTTEVKRLAVGSFMPDFTSSGY
>A0A7G8QKL1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. JUb54|TrEMBL
MESLLNLPLAGETRVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFAVPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGQ
HWQILLLDSQVFGVPHGELSDFQLEWLEQRLAEEPERYTLLLLHHHPLPSGCSWLDQHSL
RNAGALDRALTAFPRVKHLLCGHIHQELDLNWNGRRMMATPSTCVQFKPHCANFTLDTIS
PGWRWLDLHADGTLTTEVCRLKGVKFHPDIASEGY
>A0A653JSX3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sphingorhabdus sp. 109|TrEMBL
MLMAQITDIHLGFDPDNPAEFNRKRLDQAIKAICAMTPQPDLLLATGDLVDRGDQESYQR
LENALSVVPFPVHMCLGNHDLRAPFRKQFPDVPAPDGFVQYEVDTAELRLLFLDTLEEGR
HGGAFCETRAAWLSARLSEQTDKPVILILHHPPVESGIEWMTTHPDEPWVSRLAETVAGH
DQVKGMITGHLHRNISTWWGDVSLAICASTAPQVALDLSAIDPENPDGRNMIVADPPAIA
LHYWNGRQLISHFENAEEHVMLARYDENLQPLVRALLAERPE
>A0A8C9UPG3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Spermophilus dauricus|TrEMBL
MSLLIYCWCLSPQRVRESADFGLAPMSPCGVIRRRFSGTPLLPPLSSRLGSAGEVESSAC
VVFTIDAQGVDKIHGLSPGSFDLENGLSRGRTVLDPPSGPGLGRGAQAPAPHSQRRESFL
YRSDSDYELSPKALSRNSSVASDLHGEDMIVTPFAQVLASLKTVRSNVAALAQGQVHGAV
KQASVGNPPPSSQPPPPAGNAYSGQKLALETLEELDWCLDQLETLQTRHSVGEMASNKVG
PTWIESSRSGNQVSEYISRTFLDQQTEVELPRAAPEESQRPMSEISGLRGLPHSASLSAA
TVPRFGVQTDEEGQLAKELEDTNRWGLDVFRVAELSGNRPLTAIIFSIFQVLSCLYQHSA
RHSARDKTPPALQGQRSPGLGGFGEAGTGGRLRVSGSRLCADSELALMYNDVSVLENHHL
AVGFKLLQAPNCDIFQNLGAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTS
LGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDI
SPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSP
VDTAVSSERGLPDRFQFQLALEEAEEEEEEEEEALERQPSGSPDT
>E2X7A8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella dysenteriae 1617|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A5E7Z9Z5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Roseovarius sp. EC-HK134|TrEMBL
MARFLHLSDLHVVPEGQLVSGRLDTGRLLQEAVDTLRTRLDAIGPLDAILVTGDLSEDGS
AESYAIARRELERLGHRLLVVPGNHDGRETFRAAFSDLPEIRPTGLIDWVADIADTRVIG
LDTLIEGNGGGILRAESLAFLDQALAETGGRQVVVALHHPPLRTGIRFMDAIGLENPDAL
RLVLERHQAPIWVLSGHVHGVYHGLLGRHPVVTAPSCCSAFALDLRQEAPVGFMTGPTGC
GLIDTGPGGVWTELPLRHGDGPFAF
>A0A550A204|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella eurypsychrophilus|TrEMBL
MLKEAISYSLAAGASVRIVQVTDPHLFADPSAQLLGVNTALSLESVLNTIKAVQYPADFM
LATGDISQDYSGESYHNFVRAIAPLDFPCHYLPGNHDDPRIMRLNMQGPNIYGQQRILAG
SWQIIMLDSTVRGKPGGHMADSEIDLIKSAVADQPDRHTLLVMHHNPILVKCQWLDQHCM
DNGSDFIEQVSQIPQVKGLLWGHVHQQLDKKHLGPHGAISLMATPSTCIQFKPLSSYFSL
DALQPGYRLLELKADGSMLTNVYRVPGDKFFPDRGARGY
>A0A6B9G002|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea cypripedii|TrEMBL
MDSLLTLPAASGADIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIEAQQRDYDLII
ATGDLAQDHSVEAYQHFVTGIARLPKSCVWLPGNHDFQPAMVNTLAEAGIAADKHVLLGE
HWQLVLLDSQVFGVPHGMLSEYQLEWLEKTLAKFPERHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLQNFPRARNLVCGHIHQELDLDWHGRRVLATPSTCVQFKPHCTNFTIDTVA
PGWRWFTLKPDGMLQTEVNRLQTDAFRPDLDSEGY
>A0A6M8MCV9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas graminis|TrEMBL
MSKAPFLIAQISDLHLKAGNKLTYGVVDTLGALRRAVDHLNASQPRPDIVVISGDLVDFG
RPDEYAVLHPELARLSMPYYLVPGNHDVREHLLAEFADHVYLPISAEAPLDWVVEAHPVR
LIGLDSTIPGAHGGQVLDSQMAWLDEVLGRRPAVPTLLIMHHPPFVTGIGHMDREAFING
AALEEVIGRHPQVERLLCGHLHRPMQRRFAGSISCTCPGTSHQIVLDLRDDAPAHFNLEP
AGYLLHRWNAEEGLVTHNGVFGDHPGPYPFYDAQGLID
>A0A1A8H3C6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothobranchius korthausae|TrEMBL
VDPDSFDVENGPSASCSPLDPQASPGSGLVLHTNFPGHNQRRESFLYRSDSDYELSPKSM
SRNSSIASELHGDDLIVTPFAQVLASLRSVRNNFTILTNVQCPSSKRSPAATTQPPITKV
FLPDEAYQKLAMETMEELDWCL
>A0A1A8FA47|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothobranchius korthausae|TrEMBL
DWCLDQLETIQTHRSVSEMASNKFKRMLNRELSHLSEMSRSGNQVSEYISTTFLDKQNEV
EIPSPTLREREKPMCHISGVKKLTHSSSLSNSTLPRFGVKTEHEEALARELDDLNKWGLN
IFHVADFSNNRPLSCIMFAIFQERDLLKTFRIPVDTFVTYVMTLEDHYHANVAYHNSLHA
ADVTQSTHVLLSSPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYND
ESVLENHHLAVGFKLLHEDNCDIFQNLSKRQRQSLRKLVIDMVLATDMSKHMSLLADLKT
MVETKKVTSSGVLMLDHYTDRIQVLRNMVHCADLSNPTKPLPVYRQWTERIMEEFFRQGD
KERERGMEISPM
>A0A5E1AGL8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter kobei|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQEAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPARHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLAKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLAGAQFRPDTASEGY
>A0A7U9ND33|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lachnospiraceae bacterium|TrEMBL
MKSRILHLSDIHLGNDIGITDYEIDDKLGVFRNNLMESKQNYFDILLDYLSNAGITYDFV
VISGDIVHRGQYDYSSYFNTCILKLIELKRLPNRNHIIIVPGNHDIVEGNDKWKIFEQYL
DIQFVKPIMKLNSISRNEYLQKVNNLLRKRKRSKFISNSDFPFIIDKNKKIILYAFNSCS
LCQMNNVIIDGKSEKLDLPRIDNLELDYFIYTMKSLKEIDNEYNDYLKIAVFHHHISSFT
EFEEIKSFETLSNAGIVKKTLIENGVKLVLHGHKHYPNIYLDTTASKKGGLTVVSGGSIC
EIINRKGVKQGFFDLLYDSKSPNEINQRYIELINSKRNYDRVPYEKIELPQNKSYIKKSK
KIDVANINRLILNVLEKNFVKNNNICGWDKKILDKKTVGILGTAFGIILMEMTGGNSKFY
IENKTSIINSLHHQRKTDGGFGVLFQSESSIIATCWVAQAFKISEAWDYYLKTINVLLEF
EEIKSEEIISESYESNTFTVAFLMRVLLDYYMIFQNNHVKSTIDVLYKSLKDGYLEDSQG
IRWAKNLKNDEEESIPHTCHACIALIQYQEIFKRNDEELFHILKYAKKWLLDRQDMVFVV
ERIRHNGMEVVYEHNTITWYIIALIKLGVSEFEEKVIKNVDSIMNKFDWEKGVWKYNDSY
NIWETYDSLIALREYIIFSAKY
>A0A7U9MSW1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lachnospiraceae bacterium|TrEMBL
MKKRFSLKKGVAFCTVSVLLRMLSESGPDIIVITGDLVDSTHTDIDTALAFAKEAVQIAP
VYYVAGNHEARLTEYERLRTGLVRLIPSYNFSSFSKNAL
>A0A7U9X9Y3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lachnospiraceae bacterium|TrEMBL
MRYYIADPHFFHGNLNTKMDRRGFAGVEEMNAYMLQRWNEKVRKNDEVVILGDLSWGKAE
ETNELLGKLNGRLYLIQGNHDRFLKNKDYNASRFVWVKPYEELQDNKRKVILCHYPIICY
NGQYRLDGNGNPKVYMLYGHVHDTYDQRLLEQFQEITRSSIRENPDGEKRAIPSNMINCF
CMYSDYTPLTLDEWILCDRKRREKLCAEDSM
>W3VB69|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus khanii NC19|TrEMBL
MESQFKLPVVEGTTAKILQITDTHLFAGKEETLLGINTYRSYHAVLDAILKQNADIDLIV
ATGDLAQDQSLEAYRHFADGIARLSAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGE
HWQLLMLDSQVAGVPHGELSEYQLEWMKKCLDIYPERYTVILLHHHPLPSGCIWLDQHSL
RNSHILAEYLQGYFRVKAMLCGHIHQEVDMDWNGIRMMATPSTSVQFKPHCTNFTLDTVA
PGWRYLALSISDRGEFGLTTQVHRLESNEFCPDLDSDGY
>A0A128FAV0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Grimontia celer|TrEMBL
MHERVFTIRVFKTLRISHLPSQHSQTVRLLQITDTHLFADPYGCLLGVNTAASFQAVVGE
IQSSQVEFDAIIATGDISQDHTAESYQRFVDGIAHWSQPCFWLPGNHDYQQEMHSILAQS
TLQRCDSVLVGEHWQLVVLDSQVKGVPHGRLSDEQLSLLDIALSTNKDRHTLVLLHHHPL
PAGSAWLDQHQLHNQEDFWAVVEKHNNVKGVVCGHIHQALDTEHKGRRVMAAPSTCIQFK
PDSDDFALDSTNPGWREIELHQDGTIITHVGRLKGTEFQPDMNSTGY
>A0A7H8ULI4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mannheimia pernigra|TrEMBL
MSEHFRLPINDTVRLLHITDPHLFSHTEETLLNVKTIKSFSAVIEQIKKQIEQTKQGFDL
ILSTGDLIQDQNIAGYHYFAQLTEPLKTPIVWLEGNHDVQPYMSQILGEYSHILPHKQIL
IGDRWQLLLLNTQVAGMPYGELSYRQLKWLEEKLNENPKRFTLIALHHNILPTNSAWLDQ
HSLKNSDELAKILQPFDHIKGIVHGHIHQQVDDMWNGIPIYATPSTCIQFKPNCNQFTLD
LLPQGWREILLYENGKIATTIKRLNSNDFLPDLNAIGY
>A0A2T3PTK0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium phosphoreum|TrEMBL
MQTYSLPQTNPESVVLLQITDTHLFANGSGSLLGVATKDSFHAVLNGVDAAARHFDAIVA
TGDISQDHTPYSYQRFADGISRWSQPCFWLPGNHDFQPTMQSILPSEQIKPQQQVLVGDH
WQMILLDSQVQGVPHGELSAAQLVLLDAALARYPDRHALILLHHHPLEAGSAWLDQHQLH
NNSGLWKVIDDHPQVKAVLCGHIHQDLDRTYHGVRVLATPSTCIQFMPDSDDFALDHNNP
GWRYLELINDGQIITSVHRISGDQFKPKLDAEGY
>A0A4R3Y3C5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Testudinibacter aquarius|TrEMBL
MRTTFLHHSDKLPVRFIQVTDPHLFADKKAELLGINTFDSFKAVLSEIQQTPFTFEFVLA
TGDLTQDNNPEGYRYFSEEISQLQKPVFWIPGNHDYQPHMVETLNRYPEFISPLKHIIVN
NNWQILMLDSQVLNVPHGYLNQYQLDWLIAKIEQYPDLYTLVVLHHHIAPTRSAWLDQHN
LRNTSEFLSCLQQHCHIKAIISGHIHQEMDTLWNNYRILTTPSTCIQFKSDSYHFNLDIL
PPGWREFELYPDGSLITQVKRLKHNLFVPDFNISGY
>A0A2T3K0N1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium phosphoreum|TrEMBL
MQTYSLPQTNPESVVLLQITDTHLFANGSGSLLGVATKDSFHAVLNGVDAAARHFDAIVA
TGDISQDHTPYSYQRFADGISRWSQPCFWLPGNHDFQPTMQSILPSEQIKPQQQVLVGDH
WQMILLDSQVQGVPHGELSAAQLVLLDAALARYPDRHALILLHHHPFEAGSAWLDQHQLH
NNSDLWTVIDDHPQVKAVLCGHIHQDLDRTYHGVRVLATPSTCIQFMPDSDDFALDHNNP
GWRYLELINDGQIITSVHRISGDQFKPKLDAEGY
>A0A1U7CJ97|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paludisphaera borealis|TrEMBL
MMNVGSSTIRCTFLVLLTAAVGCGSSSHSQAETNPAGAFVVKPYIQLGDPADPRKIDGLD
VVWHAADVDAGWKVEYRAADDQPWRSTDAPRSQRIAVVGQPPHRVYRAGLRDLTPGGVCS
YRVIRGDEVVFSSTVKSPKAKEQPHRFVVFGDCGAGTPGEKAVAYQVHSANPDYVMITGD
IVYSRGRVSEYRDKFWPVYNADEASRDVGAPLLRSTLFLAAAGNHDIADRDLGKNPDGLA
FFFYWDQPRNGPALRDGGPHVPPLRGPEENQKAFRESAGDAYPGAGNFSFDYGNAHWTVL
DTNAYVNWTAREMRAWVERDLAAARDADWRFVSFHQPPFNSSKAHFADQLTRVLADVFEA
GKVDVVFSGHVHNYQRTYPLRFTLAVDAAGRAVKPGELLGGSFVLDRAFDGRTMTRPQGV
IYLVTGAGGATLYDPSQQDDPDSWQEFTCKFVSKIHSLTVADVQGKTLTVRQISADGNEL
DKFSVTK
>A0A4W5LB55|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hucho hucho|TrEMBL
MHIFPLKQTENQMIDIELENGVSPGHTPLGSQSPSLTLHPSFPQGGRRESFLYRSDSDYD
MSPKNSVSRNSIASEGHAGEDFIVTPFAQVLASLRSVRSNFTLLANVSMPTVKSVLTCQS
KHLTAGLRPKSNAI
>A0A5X3QYL0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Saintpaul|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A131YHR4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rhipicephalus appendiculatus|TrEMBL
MGCTQSAIQRRAGGRAGRGGPATPVPTAAGVPPSASDLSAATNNSASNNRCRAPPSASES
QPQHRNSRPQCLEGARPLFRRATNWEVVTERNVPLFAVLDGAPDDGRKGTVALKFGSMYL
TVPSVKVMFVFGKEDAQYNALKWAADKMHYECTLSSTSEAAIDNYLNGQPHLVFVDARSK
STIDPVTLCRTLRGFRGSQFTCIIAVVKKGLADKEEAAVIPLLKCGYNRWFAETCSLGVC
LNEMIQIEHNDLINLWKLRASEALFSALHYARDGVIVTGAAHEIQYMNRAAEKLVGYSVE
EMLGVDAQELHRTDSLKTEVATTICTQLKKGKEWEGTLFHKRKSGECIPMWSKIAPVEIH
TGKSDHVVYIKECPFFLEKPFSPDADFLSFTLNSSMKSSRKASCDVRSLCSEVGMNRRQS
FAKFHAMTLEAPITKVINMLVSTQENSSAMVAQALDRVIEILRSTELYNPQLGVGQGKSE
DQMTSDLVTGLINTGQKPTGVRRLSHETSLMKVNVVNATASSGVLPSLQTAPSKIKDLLE
NDVKWEFDIIELETLTGRRPLIWLGLSIFSKLNVHTSLECDDATIRNWLQLVESHYLDNP
YHNSTHAGDVMQATAYFLLKLRKKDIFDPLDEAICLISAVVHDIDHPGKSSAFLCNSDHE
LAILYNDRSVLESHHAAFAFKLTLSDEKVNIFQKLDRDVYRSVRLSIIDMVLATEMTKHF
EHLSKFLNAFQKPMQEEEGFEAEPLQEHGESASLRSAENIILIKRMLIKCSDVSNPARPI
NLCIQWAHRIAEEYCAQTDEEKRRGLTVVMPAFDRATCSIPNSQTGFINYFVRDMFRAWS
DFGEFPELMEYIEKNYIYWKDKEPSSSQQGNR
>I3MY04|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ictidomys tridecemlineatus|TrEMBL
MEAEGSSVPARAGSGEGSDGTGGATLKAPKHLWRQEQHHQYPLRQPQFRVLHPHHHLPPP
PPPSPQPQPQCPLQPPPPPPLPPPPPPPGAARGRYASSGASSRVRHRGYSDTERYLYCRA
MDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLDPMTSPGSGLILQA
NFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
AALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLKELDWCLDQLETLQTRHSV
SEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRP
MSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPL
TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST
PALEAVFTDLEILAAIFASAIQDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGF
KLLQEENCDIFQNLTKKQRQSLRKXXKKNVLATDMSKHMNLLADLKTMVETKKVTSSGVL
LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMC
DKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAP
DDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPL
DEQVEEEAVGEEESQPEAPVIDDCSPDT
>A0A0Q2QY74|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio furnissii|TrEMBL
MLNVSSSLENSDSIKLVQITDTHLFAPDDGSLLSVNTADSFLAVVEAISAQRLEFDAILA
TGDISQDHTAESYHRFAQGIQPLEKTCFWLPGNHDYKPNMGSVLPSEQIHAPDHVLLGDH
WQMILLDSQVVGVPHGRLSDQQLALLEAQLSAHPTRYTLVLLHHHPLLVGSAWLDQHTLK
DSEAFWAIVERHQNVKAVLCGHVHQDMDRMHHGVRVMATPSTCVQFKPNSDDFALDKCSP
GWRELALHADGRVTTQVKRLAKGQFQPDFTSSGY
>A0A8C2WN99|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyclopterus lumpus|TrEMBL
MLNRELSHLSEMSRSGNQVSEYISSTFMDKQNEVEMPSPTLKEKSMSHISGVRKLSHSSS
LSSSSMPRFGVNTDHEEELAKELEDLDKWSFNIFRVAEFSNTRPLSCVLYTIFQERELLK
TFRIPVDTFVTYVMTLEDHYHGNVAYHNSLHAADVTQSMHVLLSTPALDAVFTDLEILAA
LFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLHQEHCDIFQNLT
KRQRQSLRKLAIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDHYTERIQVLRNM
VHCADLSNPTKALPLYRQWTERIMEEFFRQGDKERERGMEISAMCDKHTASVEKSQVTLG
VKTTICPFFFFTNIQ
>A0A1H5XG48|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio hangzhouensis|TrEMBL
MKTAPSDESQFSCVRLLQLTDTHLFAPQDGCLLSVNTQESFNAVVSEVISQGSVFDALLA
TGDISQDHTEASYEKFVAGIEPLALPCYWLPGNHDYKPCMNSVIDSPLIQDVTHALLGEH
WQVILLDSQVVGVPHGRLSDAQLEFLDRKLSEYSERHTLVLLHHHPILVNSAWLDQHTLK
DAHEFWEVVEKHTNVRAVLCGHIHQELDQKRGDVRVLATPSTCVQFKPNSDEFALDTRSP
GWREMELYSDGNVVTKVKRLANGAFRPDFNAEGY
>A0A8C2XI30|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyclopterus lumpus|TrEMBL
MVSGGSAMDMDPLGPEYVSMCLLADESYQKLAIETMEELDWCLDQLETIQTYRSVSDMAS
NKVGQFILHIINSHSVVVYDQAPHFMDLLS
>A0A1A7Q2Z7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gallibacterium salpingitidis|TrEMBL
MSDLFQDESTGVIKLLQVTDPHLFADANGELLGINTYASFQQVLSEIKSSGFESDFILAT
GDFVQDGSEEGYHRFVKEIAQLGKKVFWIPGNHDFQPKMEAVFDVYKAIIQPQKHLLLGE
QWQVILLDSQLYGVPHGMLAEDELTWLEQRLAMYPDRNTLVVLHHHLLPTRSAWLDQHNL
RNPYDFSEVLAKHKKIKGIFYGHIHQEVNGEWQGIPVFATPSTCIQFKPDCAHFTLDNLQ
PGWREITLYPDGHLETRVQRIKEKVFLPKDNMNGY
>A0A8B9Q2S3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Apteryx owenii|TrEMBL
GGQGSFDLENGPSGRGSLDPQASPGSGLVLQGTFAHGQRRESFLYRSDSDYDLSPKAMSR
NSSIASDLHGEDMIVTPFAQVILASLRTIRSNFAVLTHLQDRAGTK
>A0A2D4GV66|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micrurus corallinus|TrEMBL
AALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSV
SEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKLP
MSQISGVKKLMHSSSLTNSSIPKFGVKTDQEDILAKELEDVNKWGLQVFKIAELSGNRPL
TVIMYTIFQERDLLKTFKILPDMLITYLMTLEDHYHADVAYHN
>A0A7X1DYC7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas cremoris|TrEMBL
MPSVSTVTPDAPALLVQLSDSHLFAEADGTLLGMNTHESLQRVIDLVRAQQPQIDLMLAT
GDLSQDGTLESYQQFRDMTQQIGVPARWIPGNHDEPQVMALAAMHSDFLEPVVDIGNWRI
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPSRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERVQGFAFTVDYGSNGY
>B5XU51|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pneumoniae (strain 342)|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQASGISPAKRVFLGD
HWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDRALSAWPRVRHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAEFHPDIASEGY
>A0A8G0WSF6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. S07E 245|TrEMBL
MPQPNHPHAPINVVQLTDAHLFADPAGTLLGLNTRGSLQHVIDQVHREQPAIDLLLCTGD
LSQDASATAYRAFAEMTATLRAPARWLPGNHDQARVMAEVAQGTDLLQSVTDVGNWRIIM
LDSAVVGATHGLLAPAQLAVLDQALNSVPQRHCLICCHHQPVDIGCAWMAPIGLRNSDEL
LQRVQAHPQVRAVLWGHVHQAFEQTRDGVRYMATPSTCIQFAPGSVDFKVSEELPGYRWL
RLHADGQLETGVERALDYVLQLDFNSPGY
>A0A6H0T8E3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurellaceae bacterium RH1A|TrEMBL
METIYQLVPEKSTISLLQLTDMHLFADSQGELLGVNTAQSFQAVLEAIGAEGGQFDALLA
TGDLIQDNNEAGYQRFAQMVKPLGLPTFWLQGNHDCPTSMPHKLAEQPHIFPHKVILAGQ
HWVILMLDSQVYGSPHGRLGSYQLSWLSQMLTQFAGRHALICLHHNLLPTHSAWLDQHSL
RNLHDLEDCLAPHTNVRAFLHGHIHQEVDSHWLHYRVLATPSTCIQFKPHCNTFTLDMLP
QGWRELVLKEDGTIETLVKRLATNEFLPDFNSAGY
>A0A6I7NBV4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonadaceae bacterium|TrEMBL
MSGDGHQQTIHLVQLTDCHLYADEQTELLGLDTHASLQAVIDQVLQQIPKIDLVLATGDI
AQDASESAYQHFMQAAKRLPAPCHWIPGNHDDALRMSELGAADELTQPWHDLGPWRIVML
DSSVAGSVAGRLAPAQFELLEQALASAGDRFILLTLHHHPVDIGCDWMRPIGLHNADQLF
QRIEHDPRVKVVLWGHIHQDYDEQRGHLRLLATPSTCIQFAPNSHDFSTDTQAPGYRWLR
LHADGSLETGVERVAQGRFVADPEASGY
>A0A0B6X6S8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus bovienii|TrEMBL
MESLLKVPVAEGATARILQITDTHLFASKGDALLGINTYRSYHAVLDAILEQSIDIDLIV
ATGDLVQDQTIGAYQNFAEGIARLPVPCVWLPGNHDYQPTMVDVLAAAGISPSKQILIGQ
HWQLVMLDSQVQGVPHGELTDYQIEWLQKCLDEHNDRNTIVMLHHHPVPSGCTWLDQHSL
RNAPALAESLKDKRQVKAILCGHIHQELDKMWNGIRVMATPSTCMQFKPHCTNFMLDTVA
PGWRYLELSVAGNREAKLQTQVHRLKSNEFCPDLDSDGY
>A0A7R8UBM1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hermetia illucens|TrEMBL
MEDDRDESASIGCMGKFAMFFRHTSKVSINNTSTVDASSPSTKKRGYKRNRGTNNIITDR
KNSISKNNSKSESSLIDLKKQLEARMIEGSATEATGPHTKADILDNIVFSQSTNRRNDSA
DSDDTKLLSGVTATGDTGDKASRSDKAINNATRGTTIIPPTPYGNIPIIYNVCNTKTVGG
EKEKNIEIRDDDYDSSEEVLLRKRVSISRSDKDFADEMNDSVPPLRRPRQMRTYGSASGT
PIPIRPDIAELIRTLDPDALRINQLISDDKANTGGGVEGWDTQTVGISVQGLDIHCNNKS
SDGVNPITKSRPAGTSLFERRVPTGERLSLYIGGKTDLGNGHRKKKEKPLMDLKHPTVLP
PNPQLKALLIFHKADSVCETFNNACHRHQLEVTLVKTKETALEAFQNNTAGSHHLIIIDA
RYPKYLDAEYIARSVRHTPGCHFTTIIGIVKKSFFEKDEASLNALLDAGVNRCIVETQNI
SVCSTELKQVLHSIVRPQHVMSTQQALYTALHRLKEVLIITDDLLRIQYANKSAERLLNM
RLDEVISRPLSDIFLSDLSSLKNRRDFDGILTVKRKGHDGIAMHVRGVPVACIGRAPTHY
VLNFDVPGGQADFIASLPQPKEAPRGSLHSIRRGSFDVRSVASDGLRRTSLAKLTSLPLE
APITKVVNLLSQVQENCSQEEARLIDKVLEFLKREGLYSPQMKEIKTEDPIATDLIGALL
TGPTNLYSSRRSSNDSIMRVSTSRASGILPAKMKANSQIMAMLEESLDWDFDILKLEEIT
EKRPLLYLGMEMFRRFDVFATFNTDENTFKTWLAVMEAHYFAQNSYHNSTHAADVMQATG
VFLHQLAEKNLAMDRMDEATALIAAATHDIDHPGRSSAFLCNSDSPLAILYNDLCVLESH
HAATTFKLTLGDDKINIFKNLDRETYKVARSVIIDMILATEMTRHFEHLAKFVSVFGTDE
PRDLAQSEDDNQILIRRMLIKCADVSNPARPLPYCVEWARRIAEEYFTQTDEEKARSLPI
VMPMFDRATCSISKSQIGFIEYIIQDMMHAWDSFIDMPQLIHHMQYNYSQWKKYEEQGIH
TLADIKNKQTTLNAKKSIAK
>A0A7W3E4Q4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter freundii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQCVLDAIHAESTDFDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVYGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPSGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIS
PGWRTLELFADGSLHTQVCRLPGIRFHPDTASEGY
>A0A2L2K4S4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio diabolicus|TrEMBL
MQSSSDSIKLLQITDTHLFAADEGSLLSVKTADSFNAVVADVLRRNVTFDYILATGDISQ
DHSAESYQRFAEGIEPLEKDCFWLPGNHDYKPNMGSVLPSQQIKAAEHVLLGAHWQLVLL
DSQVVGVPHGRLSDQQLALLEEKLAEHPERHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
HVVDRFDNVKGILCGHVHQDMNVLHNGIRVMATPSTCVQFKPNSDDFALDTTSPGWRELQ
LHACGDITTQVGRLPDGQFQPDFSSNGY
>A0A2T0ARI6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clostridium thermopalmarium DSM 5974|TrEMBL
MKIGLYAISDLHLSLSSDKPMDVFGEQWNNHHERIRENWIKKINDKDTVLIAGDVSWSMK
MEDGLADLEWIHNLPGRKIISKGNHDYWWGSISKLNNLYEDISFIQNNFFSYEDYAICGT
RGWTIPGDKSSSHDIKIYNREQIRLKLSLDKAVSSGYSKIIVMIHYPPVNDKFEASNFTE
IFEEYGVEKVIYGHLHGPSLNRVFEGTYNGVEYIMTSCDYINFDPIKVI
>A0A2P8A3G7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces sp. 111WW2|TrEMBL
MTIRVAAVGDIHMGPDSEGLLRPAFETLPDCADMLLLAGDLTRHGTPREARVVAREVRDL
PVPVVAVLGNHDHHDERPEEVTAILRDAGVTVLEGEATVVECAGGRVGIAGTKGFGGGFV
GRSAGEFGEPVMKEFVRTTRRSADSLHAALKQLAEEDCAARVALTHFSPVADTLAGEPPE
IHPFLGSYLLAEAIDTAGADLAVHGHAHLGTEHGMTAGGVRVRNVAQPVIRRAFNVYRLD
GD
>A0A653HX64|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moraxellaceae bacterium 17A|TrEMBL
MTLLPSSISQHHADYFSIIELSDLHLFNDPNKLMNGVNTADTFASVLSLVRQQRDDVDLL
VLTGDLCHEPTPQNYDRLFATLDDVNIPFIAIPGNHDVTLELDHHLPFAQRRHLPVKADT
RLQNCYSIATDYWDLLLLDSSCEGHSHGKIDEHSLRWLAQKLANANRPCAIFCHHPMVLI
DSAWLDEYTLINADRFWEVVMPYLDRIKAIFVGHIHQEMHKITYGTSVFGCPSTSLQFKP
LCKDYTIDEIAPGLRWINLYNNGLLATGIKRTDTI
>Q1Z4U9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium profundum 3TCK|TrEMBL
MQKYSLPQTNPNSVVLLQITDTHLFADESGCLLGVATKDSFNAVIDAVDASARPFEAIVA
TGDISQDHTDESYQHFSDGISRWSQPCFWLPGNHDYQPAMHSVLPSPQIKSCEQVLAGDY
WQVILLDSQVQGVPHGELSEAQLLMLDATLKAYPERHALILLHHHPLVAGSAWLDQHQLH
NNEAFWQIIDKYPKVSAVLCGHIHQELDCIYHGVRVLATPSTCIQFLPDSNDFALDKTNP
GWRYLELTREGQLNTDVCRLQGRRFIPLFNSAGY
>A0A2X4D9X1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYTRFVEMMRPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGKH
WQAVLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTQVKRIQQTEFLPNMQEEGY
>N9VQE4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas diversa CDC 2478-85|TrEMBL
METERLQAPDGCVRLLQITDTHLFANADSQLLGVRTADSLAAVLERVQSNAHPFDCILAT
GDLSQDHTAESYQRFATMMAPLGKPIYWLPGNHDDAPLMTQQLYEAGISEAKWLVGEHWQ
IILLDTQVRTKPHGVLADHQLAALDHALRTHPDKHALIALHHQGVPVGCAWLDQHNLKNA
DDMFAVLARYPQTRTLLFGHVHQEFDEVHRGIRLIASPSTCIQFKPLCDDFTLDESGPGW
RYLTLHPDGRIDTQVWRLPAGSFIPDSQARGY
>A0A2S9RDG6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENHEFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNVAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELYSDGSIRTEVKRIQQAEFLPNMQEEGY
>A0A5J6W0S0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. E76|TrEMBL
MESLLNLPVADGASVRILQITDTHLFAQKSETLLGVNTWSSYQAVLEAITAQQRPCDLIV
ATGDLAQDHTPEAYQHFAQGIAAFSAPCVWLPGNHDFQPAMFSALQDAGISPAKQVLCGE
KWQILLLDSQVFGVPHGELSEYQLEWLEAKLAENADRFTLLLLHHHPLPAGCSWLDQHSL
RNAGELDAVLGRFPNVRHLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTQVERLEGTQFNPDTASEGY
>A0A750KGN4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLTDAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELHANGLLETEVHRLQDTRFRPDTASEGY
>A0A6J1MAI3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila hydei|TrEMBL
MRNCLPKIFRTKSSSSVSSASSARAAAVHSNELDADSDAERYVVAKTKTTATTTTLKGAA
DQRLDKNANKKLHQQQQQQQQPQQPPATTTTTTSTTSTSTTSSADDVDKNRLISADKIAN
STSLDLETSNNSHNHSQSNSNSNGNGNGNQTATNGSIRQVHDTNPTSEMKVACGEILLPA
PVPVPLSLPLAVPAPTSISVPVLPGNSSKTPEQMEREYEANEAAEGRDIMTPLLRSTRSL
SMAFASGAGPGGGGGCGGGAAGVGRIMQPEIVEAIRNLDTQALRLNNLTLEDRVKLTQRQ
DAKAKENNDNVTLRPKVFTFDRQTHSLYERRLHKGPKLRLWVGNGKKPSPQTEEDEFKSF
QRNLMDLKYPTVLPPNPQLKALLVFHKSDSICEVVTLACQRHQLDVTLVKSKEEALETLH
KSYATAQCYHLIIIDARSTKGLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDALIAL
LDAGVNRCIAETTNLTLCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVL
RIQYANRATERLLNMRLDEIISKPLGDIFVSDLSTISEQGKSIKEFDGILMVRRKNQESI
PMHVRVVPVACIGSAPTHLIFNFDIPGGGMDFIATLPQPKEAPRGSLHSVRRCSFDVRSI
ASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLDFLKREGLYSPQ
MKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGNSTRTATIVPAKMKANPIIME
LLEESLKWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYH
KSNTYHNSTHAADVMQATGAFITQLASKDMVMDRMDEATALIAAAAHDVDHPGRSSAFLC
NSNNPLAILYNDLTVLESHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATE
MTRHFEHLAKFVSVFGNEMEPRELVQSEEETSILMRRMLIKVADVSNPARPMQYCIEWAR
RIAEEYFMQTDEEKQRHMPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWDGFIDMPEL
ITCMQINYSQWKKYDEQGVNTLADIMAKQPPVGNKSSSSK
>A0A6G0TN44|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aphis glycines|TrEMBL
MRSMLAQQDAVLAALDKTKDLVIITDLKHNIQYMNKSGSVILGYGAEDVINKPLAVFHQL
CDIDQITKKLEKNIEWDGKVSWKCKSGEHVYLHCRASPFRSFGKETTNYIYIQESIVDVH
GFPRGSVPSIRKGSYDLKSINSDGAQSARRQSLAKLHNLPLEAPITKVISLICTAQENSN
DQVVQILDKVVDILRVTELYSSHLKTENIKYDDPVTSDLIGALITQGPVHVTSTRRSSND
SATVKSQPYGLGVAKMNFMTSVTPQIKELLDMSLYWDFNVFKLEELTMKRPLVHLGMNLL
THFEVHKTLGCDERTLHAWLTVIEGHYHAKNTYHNSTHAADVLQATAMFLEKDRIKRLLD
QLDEACCLIAAITHDIDHPGKSSAFLCNSKNDLAILYNDISVLESHHAALTFKLTTKDER
LNIFKGLEKDTYKVVRQNIIDMILATEMTKHFEHLAKFVSVCNKPSTLDEAPVDGLTPSE
VSPETIMPTSAEEINLVKRMLIKCADVSNPTRPLKMCVEWAKRIAEEYFNQTDEEKLNHL
PVVMPMFDRASCSIPKSQIGFMDYIINDMFETWDSFIDMPEMLYYMRSNYQYWKDLEEKG
TISFNDICKIMTTTLPKIPESSGNH
>A0A811GXG7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter mucicolens|TrEMBL
MLIAQITDLHMRTPGDKAYGVIDPAAFLAPAVLALNALTPRPDCVLITGDLTDLGKPIEY
QTLREHLQALEIPYFLMPGNHDDRAQLRAAFPDHAYLQDGGPFVQYAIETYPLRLLALDT
VVPMKSHGELCQTRLDWLAERLAEQPGRPTLVLMHHPPFLTGIEHMDDIGLLAGAPELER
IVARYPNVERVLCGHLHRTIFQRFGGTIASTCPGTAHQLALELGPRPTLQYIMEPPGYQL
HWWQGGNLVTHHAVLGDYPGPYPFG
>A0A4Q0YMI4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Veronia nyctiphanis|TrEMBL
MLFCQIGWHTVCVAVSQSKILFFNGTNCSIIIGIFKTLRTHERLEGNRDFIRLLQITDTH
LFSDEQGSLLGVNTLDSFRAVVDVVRQETQSFDAVIATGDLSQDHTTESYRRFVDGISLI
DKPCYWLPGNHDNQPEMQQILAVKPMVKASTVLLGEHWQMVLLDSQVPGVPYGELSEQEL
DNLCTALDAYPERYTLILMHHHSVLAGSAWLDQHRLKNADIFWQRVANYPNVKAVVGGHI
HQALDNVHQGVRVMASPSTCVQFKANSDDFALDNSNPGWRWLELHADGELVSDVERLNGC
QFKPDMLSSGY
>A0A2A7TY86|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Edwardsiella tarda|TrEMBL
MESLFHLAVASGAPVRLLQITDTHLFAGPQETLLGVNTYRSYQAVLAAIRAEAQPFDLIV
ATGDLAQDHSSAAYHHFAAGIATLQKPCLWLPGNHDFQPAMVDALAQAGVQASKRALLGD
QWQIVLLDSQVVGVPHGELSDYQLEWLEQALLSEPQRHTMILLHHHPLPSGCTWLDQHSL
RNAHALDEILRRHPRVKTLVCGHIHQELDLDWNGCRLLATPSTCVQFKPLCTNFTIDTIS
PGWRYLDLYPDGRVTTAVHRLAGNEFRPDLDADGY
>H0YCV7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|TrEMBL
XHGDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQGRPCHKV
YLDVSR
>A0A1Y6L2M3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium aquimaris|TrEMBL
MQTYSLPQSNPDSVVLLQITDTHLFANGSGSLLGVATKDSFHAVLNGVDTAARHFDAIVA
TGDISQDHTPYSYQRFADGISRWSQPCFWLPGNHDFQPTMQSILPSEQIKPHQQVLVGEH
WQMILLDSQVQGVPHGEVSAAQLALLETALARYPDRHALILLHHHPLEAGSAWLDQHQLH
NNHQLWNVIDKYPQVKAVLCGHIHQNLDRIYHGVRVLATPSTCIQFMPDSDDFALDDNNP
GWRYLELTHDGRIITSVHRVDGDQFKPKLDAEGY
>A0A8C0LGX2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Canis lupus dingo|TrEMBL
MCWGIRGLSSQGSRRLGSDGLRQGGGGSIDPLDPMTSPGSGLILQANFVHSQRRESFLYR
SDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKR
SPMCNQPSINKATITGKEDLVASSSSVWKKNMSSNIRLTNFILQFCSFKEIGPCSLST
>A0A426QI33|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Thiohalobacter thiocyanaticus|TrEMBL
MSSNDSISFLQITDTHLYADGEGRLKGVRTDRSLRAVIEQVQAQAPAFDFIVSTGDLVHD
DSDAAYERFRGHLQRLGKPVFCLPGNHDEADRLQRHLNDDTFHCNRSLRVGPWLLVFLDS
SLPGSAGGHLSEAELDALDRTIRGHDARHVLICVHHHPRLLGSAWLDTMVIDNGDELLRR
AVRHGRVRGILCGHIHQEYDTEQLGIRLLGTPSTCIQFLPGSDHFALDTATPGWRWLRLQ
PDGTIDTGVVRLPAPTDPLDPEAEYG
>A0A0N0ZBQ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moellerella wisconsensis ATCC 35017|TrEMBL
MDSLLRLTAKNEKAVRILQITDTHLFADTENTLLGVNTHDSYHAVLDAIQAQGLEIDLIV
ATGDLVQDQSIGAYHRFAAGIARISAPCVWLPGNHDYQPAMFDSLKAAGISSAKQIVIGN
EWQVLMLDSQIQDVPHGELSDYQLEWMKACLDNNSERSTIIMLHHHPLPSGCTWLDQHSL
RNSHILADYLKGYHQVKAMLCGHIHQEMDEDWHGIRLLATPSTSVQFKPHCTNFMLDTAA
PGWRYLELLIDEQGRKQVTTEVYRLSSRDFCPNLDSDGY
>H8NPG7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rahnella aquatilis HX2|TrEMBL
MESLFTLPLVNGAKVRILQITDTHLFAGEDETLLGVNTFNSYRAVLDAIKAQQREVDIIA
ATGDLAQDQSVEAYHQFARGISELTAPCVWLPGNHDFQPAMVNALQDAGISPSKHVLLGE
HWQIILLDTQVFGVPHGELSEYQLEWMERCLNAYPDRFTLLMLHHHPLPSGCTWLDQHSL
RNAHMLANTLVNYPKVNTLLCGHIHQELDLDWYGRRLYATPSTCVQFKPHCTNFTIDTVA
PGWRYLDLYPDGRVETEVFRLETNEFHPDTESDGYE
>A0A1S1HNL3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia stuartii|TrEMBL
MDSQLEVTARNAKVVRILQITDTHLFADTANTLLGINTHQSYHAVLDAILQQNLPIDLIV
ATGDLVQDQSPQAYQHFAQGIELIPAPCVWLPGNHDYQPAMVNSLKLAGISCAKEILIGS
EWQILMLDSQLQDVPHGELSEQQLEWMKKCLDSQPQRTTLIMLHHHPLPSGCTWLDQHSL
RNSHMLAEYLKGYPQVKAMLCGHIHQEMDEYWNGIRLLATPSTCVQFKPHCTNFELDTVA
PGWRYLELTVDEHGDRQVSTQVYRLNTQKFSPDLDSDGY
>A0A6V8LZP0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Desulfovibrio sp. FSS-1|TrEMBL
MTLLGFRGVHPLALLFLPAALAAVFGGFWLLRRHRAALGAPALRIWLAAWIASALGAACF
FPLVRAAHAKYLLIYYLCVLACFAALTLGLALKISLGRAAASHLPARRRLLAGGLLACAG
AACTKALAETSAGEAVVEERRIRLERHPEAHRGRELRLSMVTDLHAGFFLPQAHLAQALR
HVEAFAPDAVLFGGDLVEYELEHLAETEHFLRELARVAPVFAVLGNHDIYVDGGRVARFL
SVCGARVLRGESVPLAGPWGRFTLAGLRDAYEPERSWRCLEGQDPATTLMLAHNPQMALA
APEGLAPWLTLSGHTHGGQLRLPVIGAAINQADRRIGPGLGTVDGRRMVVSAGLGYAGLP
VRLACPPDVTHVVIA
>A0A7Z2FTB3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter asburiae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLVAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLTGAKFRPDTASEGY
>A0A4P7P0J2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hydrogenovibrio crunogenus|TrEMBL
MKIVHISDSHGRHRNLTEAIEAIERIDVLIHSGDFSDYGIKEETEFFLEWFKSMPAKHKI
LIAGNHDDTFFHSSNVSKEFDLTGIDYLQDELIEIDGVTFYGSPWTPSPFGGSFTFYPGE
GETIWQKIPDDVDVLITHGPKFKTLDLVEKYDRTQRLGCPSLAERIDQLDNLKAHLFGHI
HEAKGIMTDNGIQYSNSATGLHVLELDEVGSE
>A0A6N3LQ37|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio nigripulchritudo SFn135|TrEMBL
MKLSLDSSRDIKLLQITDTHLFEPEDGCLLSVNTFESFKAVVNAIRSNEIEFDAILATGD
ISQDHTAVSYQRFEDGIALLKKPCFWLPGNHDFKPEMHSILPSTQIQTTQHVVLNDKWQI
ILLDSQVEGVPHGRLSEEQLALLDAKLSEYPNHKTVVLLHHHPVLVGSHWLDQHSLKDAD
AFWSILSKYDKVEAVLCGHVHQDFDVIYQGVRVVATPSTCVQFKPNSDDFALDNLSPGWR
MLTLTHYGELELEVGRLPDGEFLPDFSAGGY
>A0A2J0PYD4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter hormaechei|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEKRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGD
QWQILLLDSQVFGVPHGELSDYQLDWLETKLAAEPNRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDGVLAKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLAGAEFRPDTASEGY
>A0A7A6LMR7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVLHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A2Z4RUP3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MPSVSTLTAADPALLVQLSDSHLFAEADGALLGMKTRESLQKVIELVRAQQPRIDLILAT
GDLSQDGTLESYQQFRDATRQLDAPTRWIPGNHDEPLIMAEAAVESALLESVVDIGNWRV
TLLDSAVPGSVPGYLRDDQLQLLARSLSEAPQRHHLVCFHHHPVSIGCAWMEPIGLRNPD
ALFAVLDRFPQVRAVLWGHVHQEIDQFRNDVRLMASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGRLETGVERVTGFDFQVDYGSNGY
>A0A4R5T1J4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MPHPDPLQAPVHVVQLTDAHLFGDATGTLLGLNTRDSLRHVIAQVRREQPRIDLLLCTGD
LSQDGSVASYEAFRQLTGEIQAPTRWLPGNHDEARVMAEVAPELVQAVTDIGAWRVVMLD
SSVLGATHGLLEPDQLALLDQALASAAGRHCLVCCHHQPVDIGCAWIAPIGLRNADDLLQ
RLKGYPQVKALLWGHIHQAWDEQRDGMRYLATPSTCIQFAPGSEDFKVSEELPGYRWLRL
HADGRLETGVERARDFEVRLDFDSPGY
>A0A077ND96|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus bovienii str. puntauvense|TrEMBL
MESLLKVPVAEGATARILQITDTHLFASKGDALLGINTYRSYHAVLDAILEQSIDIDLIV
ATGDLVQDQTIGAYQNFAEGIARLPVPCVWLPGNHDYQPAMVDVLAAAGISPSKQILIGQ
HWQLVMLDSQVQGVPHGELTDYQLEWLQKCLDEHNDRNTIVMLHHHPVPSGCTWLDQHSL
RNAPALAESLKDKRQVKAILCGHIHQELDKMWNSIRVMATPSTCMQFKPHCTNFMLDTVA
PGWRYLELSVAGNREARLQTQVHRLKSNEFCPDLDSDGY
>A0A6J5B992|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia sediminicola|TrEMBL
MSSHHSSDPAFNPSRRGALKCLAFGGVGTVFVLAGGILTPVELALAADAKSSATSMGVPL
FLQISDSHIGFNKEANPDVAGTLKQTIDYVNAMPVKPALTIHTGDITHLSKPAEFDLAAQ
LMSGLNITELHTVPGEHDVTDGPGTEYFSRFGKASDNKGYYSFDHNGVHFVALVNVMHFK
PNGLGGLGDDQLAWLENDLKGRSSSTPIVVFAHMPMWTIYEPWGWGTGDAGQAMSYLKRF
GSVTVLNGHIHQIVSKVEGNITFHTARSTAYPQPTAGNGPGPGPLTVASDELPKMLGVTS
IKIVRHPLKATLADTTLV
>A0A090QV68|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium aphoticum|TrEMBL
MVLLQITDTHLFADDSGSLLGVATKDSFHAVLDAIAASACTFDAIVATGDISQDHTEASY
QRFSEGIARWSQPCFWLPGNHDYQPSMQAVLPSPQIKPCHHVLAGDHWQIILLDSQVVGV
PHGELSDAQLAMLDAALTQHPERHALVLLHHHPLPAGSTWLDQHQLHNAEAFWQVVGRHP
QVRAILCGHIHQELDRIHQGVRVLATPSTCIQFQPDSHDFALDQKSPGWRLLTLHANGML
ETRVQRLDGHCFTPHFDAAGY
>A0A423TCM5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Penaeus vannamei|TrEMBL
MLSKLFKRKSGSWSKVLSERKFGNCAKRDQISIKSVEKRIRCDFQSLLRGNNDHLLSPRR
PEDNEMGPSGLPLNLQHQQSHGRTGTQAWDRYHPVQSEHGHLRLGPMKVVGQLHKVLLVF
GREDSVSEAWWLACKRQGHEVSLARNLEDTLKAFLDHTHDLIIIDARSSKHINAENICKS
IRASDHSQFAVIVGIVKRSFADRENATVGPWLKNGFNRIVTEVSTVGGVLNDLIQIEHSE
LTNQSQLRAMQAVFTALDACKEVVHITDTQHRIQYINRPCETLLGYALDDVIGRNLWELH
TSDNHKHELRTIDQRPSVDFRTSVEHQKSSVDHKSISDHRQSIDHRPSDSRVNLDISEAV
NMQMRRGREWEGLVTCRRKSGDTLHLPSKVIPVAPYARKNEFYVYTSDTHALDRLDFPSS
VDQFHPRGSIKSLRKGSYDIRSLNSDGTQNIIRRHSLVKLHSLTIEAPITRVFNIITAAQ
ENSPAYVAQALEKVLEILRSTELYSPQLISAAPDNNKPVPADPVATDLLGGLLSQGPKPL
LSGRRSSSDTATKYSQLPRPSLPLLQQQASAGMRELLAEDMSWNFDVIKLEKITDKRPLV
WIGMSLMCRFDIPNTLGCDEQTLQNWLTLIEANYHPDNTYHNSTHAADVLQCTAYFLNQD
RIKQLLDPLDVASCLIAAVVHDVDHPGKNSAFLCNTDNELAILYNDLSVLESHHAAVSFK
HTHSDDRVNIFKALDRDTYKHIRKSIIDMVLATDMTKHFEHLSKFVNMAGSSKTPVKDDD
TSSLDGASSSTLSFHSIGVVSSL
>A0A0M9FBJ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium leiognathi subsp. mandapamensis|TrEMBL
MQTYLLPQLNPESVVLLQITDTHLFANESGALLGVATQKSFHAVLDAVDTVAREFDAIVA
TGDISQDHTPESYQEFATGIARWSQPCFWLPGNHDYQPTMASVLPSEQIKPCEQVLVGEH
WQMILLDSQVVGVPHGQLSQAQLSLLDNALSQYPERHALVLLHHHPLPAGSAWLDQHQLH
NNDALWEVIEKHPQVKAILCGHIHQELDRMYRGVRVLATPSTCIQFLPDSDDFALDQENP
GWRYLELTSTGDVITHVHRLDGDQFKPTFDAAGY
>A0A5K1IJ02|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Collinsella intestinalis|TrEMBL
MPHSHSTDRTGISRRGFVTLSIAGAGVTAAAMTAPEAAYADEPALAPVVADYPNQIKIAH
LSDTHFFSRRLYSDCPDFTIAEHSDRKMFRESGDIIKKAMDEIVAYQPDLVILSGDLTKD
GELACHQDIHAMLSDAKKRLKAAGKETQFAVINGNHDINNDLNGRDFSSGLAEHTDLVDP
LAFKDLYADCGYDDAIAMFDQGGSKGGSLSYVLRPVKGVTLIAVDSCKYSTDQNGLDVDE
HVTSGVVGEKLLQWIESQAKQARAAGDIVFVTQHHGVVPHFSMEPTLMGEYLVDNYEECQ
RRYADAGVSAVFTGHMHANDIASITTEAGNTLFDIETCATVTYPSDIRFATLGWEREKGT
ANVHATLALESHPLGSVDYTDFDSGSVTRIPNIEEYGHERLLTVDVVKTMIADALVAPML
DQAAANGGVKPLLAQLAGGLGIGDGTAAALDGALFGAVFGMLPQSADEAFIVEIPILGSA
GIWANPENRRVMVQKMEAKAGVEPYALTFDAGAMAAVQSALVSEPMAAAAGWSYYISAES
LAKFLVPVYAGLDSLLVSGGRDQVLDLLRTLVETLVNQKVADGANSLFDLIKFAYGDHLH
GDETCPAWVETATAQIKLTGDDAEGNPAADGSLTSFLRATINDEVVLDKLNALLKGIKIN
LKDLLIKEKGNIAIDIALGAIKDLGAIFGLLGGTPGNMIPNIPTLADLAHGALYSLTHDE
NQLGDRVNTLATGLVDPDWKPGGGSTGGGGSGNGNGGGSGSGNGSTGGGNGNGSNGGNGT
GGSGNGDSTGGNGTGGSTGGSGNGGSTGGSGSTGGVGGSGTTGGNGGSSGNGFGTGNGPT
SGNGDSAGAITGSGKPSSCKLPQTGDTNTFAAAALMGLSALAAAIHAGSRNEALDSQDTE
>A0A8C0GG07|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chelonoidis abingdonii|TrEMBL
MLTRELTHLSEMSRSGNQVSEYISNTFLDKQNEVEIPPPTHKEREKKKKQQPMCQISGVK
KLVPSSSLTNSSIPRFGVKTDQEELLSQELENLNKWGLNIFHVSEYSNSRSLSCIMYMIF
QERDLLKTFKIPVETLLTYVLTLEEHYHADVAYHNSLHAADVVQSTHVLLATPALDAVFT
DLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEENC
DIFQSLGKRQRQTLRKMVIDMVSRAGPSLQEAQAVSLACLWGSNTHTWGWEQSRGRVGAV
PFSQPCQQSGLLGCGPGGGTGARRLC
>A0A8E2A5N4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurella multocida subsp. multocida|TrEMBL
MFSTYRYDTSAEVFKIIQITDPHLFKDEHGELLGINTFQSFSQVLHEIKASRFDYDLVLA
TGDLVQDSSREGYLHFCEQVKSLEKTVFWIPGNHDFQPKMFEILNQDQGNLNPKKHILLG
KSWQILMLDSQVFGVPHGELSQYQIDWLVAKLKDHPERYTLIVLHHHILPTHSTWLDQHN
LRNAHELAYALVPFDKVKGIVHGHIHQEMDANWQGYRVMATPATCIQFKPDHNTFTLDSV
QPGWRELELHSDGRIETRVKRIQDKTFFPNMHEDGY
>A0A8G0TW94|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella putrefaciens|TrEMBL
MLKEAVSYSIAEGESVRIVQVTDPHLFADPEAQLLGVNTSKSFAAVLNTIRAVDYPAHIM
LATGDLSQDYSAESYQQFVRAVTPVGLPCHYLPGNHDDPRIMYLHMQGEQIFGQQRILAG
KWQILMLDSTVRGKPGGHMAQSQFELIEQAIAAHPECYTLLVMHHNPILVNCTWLDQHCM
DNGAEFLERVAMYPQVKGLLWGHVHQRIDTHYEGPHGALQLMATPSTCIQFKPLSPYFAL
DGLQPGYRLLELKADGSIGTNVYRVPGNHFFPDNDSSGY
>H5V6V2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Atlantibacter hermannii NBRC 105704|TrEMBL
MESLLNLPVADKASVRILQITDTHLFAEKSETLLGINTWSSYQAVLDAIAAQQRSCDLIV
ATGDLAQDHSSEAYQHFAQGIAAFAAPCVWLPGNHDFQPAMFSALQDAGISPAKRVFCGD
KWQILLLDSQVFGVPHGELSEYQLEWLEAKLADVPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDAVLSRFPNVRHLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTIDTIA
PGWRWLELHPDGTLTTEVERLEGTQFNPDTASEGY
>A0A502LMG8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus haemolyticus|TrEMBL
MKNTFVYQTEKSIIKLLQITDPHLFKEKETALLGVNTQASFTQVLKEIQQENNTFDIILA
TGDLVQDGSDEGYHRFVEMVTPLNKPIFWIPGNHDFQPKMVEHLNKTPMESAKHLLLGKY
WQALLLDSQVYGVPHGQLSQHQLNLLEEKLAQHPNRYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLGKFSNVKGILYGHIHQEVNALWNGYQVMATPATSIQFKPDSHHFTLDNLQP
GWREIELHENGSIYTQVKRIQEAQFLPNMQEEGY
>A0A6P8MJZ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bombus bifarius|TrEMBL
MGCKTSMLECIEDTGEAEKRKHSDMVNQGSLLGKTEYDVLRRRSSFEDVAVDDDENADCS
ALKGPQNIEAHPLTNSVPSLIKILLVFPKDDQQMDVLATTSRRLGWSVSVAKDAEKAVEF
FQNRGHELVIIDHRGQRAAEADTICRAIRSSPAYHNSIIIALVKKSFLMHGEKDKIVTLD
LLETGFSRALMECSHERLLINELVGIYASALLPRTQLAAANALYVALDRCRDMVHVTNDK
HIVQFVNKISEKLLGYKTSEILGKSIADIVVYDNFVLMEQHISKGREFEGNMNCKRKNNQ
MITISCRVIPFSISLKKPTHYIYIYDTTYLSENIGSLSPTPSQSVYSRGNMIVSQRRTSD
MKSSEGRRRSSAHKLHSLQLDAPITKVISLLSNAITESTTPDTAAQIEKAIDILKTTELY
VPSLREDTDPVTTDLVGALLASPRKAWESRRSSVESTRVSMSKAFTTTTSSRMQIKSFRG
PQEIAEILERCLEWNFDIFKLEILTEKRPLLFLGTTIMNMYRVPARLGCEEKVVQNWLTV
IEMNYQSRNSYHNSTHAADVLQATARFMQSERLQQILEPLDEVATLVAAAAHDVDHPGRS
SQFLCNSDNKLAILYNDLSVLESHHAALTFKLSLSDDNVNIFKNLERDTYKQLRQTVIDM
ILATEMTKHFEHLAKFMNICSARMMDSPQLDDYTDTVDMSVVLQPENVVLVKRMMIKCAD
VSNPTRPLKCCVEWARRIAEEYFNQTDEEKRMQLPVLMPMFDRATCSIPKAQIGFVDFII
NDMVEAWDAFIDMPEMVGYMRQNYEKWKEYNDRGISTLPDIEKIQELPELRIYHLPS
>A0A3Q8XH84|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter haemolyticus|TrEMBL
MTYQVSTSSQQDFVMIQITDTHLLEYPHLEFVGMQPEQSFHAVIDLMRQQHPQIDLIVHT
GDLAQTPTPVTYNRYIQHMQSLEIPFFHTPGNHDDVAHFPFHEVDQTQLTVIELGKWVII
LLNSAQPQRIDGKITESQLRQLHTLLLKLHDRYVILACHHHPFAMQSAWIDQHKLKNASD
LLETVKPFSNIKAIVCGHVHQDAIHQWQGIEFLSTPSTCIQFKPKSEKFALDEEHPGYRY
ICLKANGELETQVYRLKTSERMSSSEVLGYD
>A0A3Q1FNW5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acanthochromis polyacanthus|TrEMBL
MRSFSELDAFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSP
KSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRASNKRSPMCNPPP
ITKTTFTGMYVGSGWKSDMITCVCE
>A0A2J9ECK2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. FDAARGOS_194|TrEMBL
MDSLLTLPAANGAGIRILQITDTHLFAGKNESLLGVNTWASYDAVLDAIAAQQREYDLII
ATGDLAQDHSVEAYQHFAEGIARLPKPCVWLPGNHDFQPAMVDTLAEAKIDARKHVLLGD
HWQLVMLDSQVFGVPHGMLSDYQLEWLDKTLALYPQRHTLVVLHHHPLASGCTWLDQHSL
RNSHQLDAVLQHYPLARTLVCGHIHQELDIDWRGRRVLATPSTCVQFKPHCTSFTIDTVA
PGWRWFTLYPDGSFVTEVERLQTDAFRPDLESDGY
>A0A7Y8PNH9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. SwsAc5|TrEMBL
MTLFPNTHQPERWTIVQISDTHLMDQDDLEFVHMNPEHSFHAVMQDITQQYPQADAIFHT
GDLAQVPVAATYQRYLKFMQALNIPHYQIPGNHDDAEVFPFYLQCNQVHAIELGNWCVIL
LNTAVKNRVDGWMDAAQLQQLDQVLQQHAHQHVIIACHHHPFDMHSHWIDQHKLKNTEEL
IDVLARHSHVKLVLCGHVHQDSLNEWQGIQFYSTPSTCVQFKPHSQHFALGTEAPGYRVL
HLNADGSFRTQVHRVEHIVQQINFEISGY
>A0A5J4F9T1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcystis aeruginosa NIES-4325|TrEMBL
MQRRKFLLISGSLGGFSLAACAHQILQPVTSKNPPESPVKQAQKAKKVKIIVISDLNSQY
GSTTYDPEIDRAIPLIINHKPDLVLCGGDMVAGQKSSLTEAAINAMWSAFDSHIAAPLRA
AKIPFGFTIGNHDASGALSAGKFIYAQERKLAQDYWQNPQHETSLNFIDKTSFPFYYTFT
QNGIFYLVWDASTHLISGQQLNWAAKNLSSSDAKNARMRLVIGHLPLYGIAVGRNRPGDY
LADAEKLRAFLEGHQVHTYISGHAHAYYPGKRGQLQLLHAGALGSGPRRLLNSEQAPRKT
LTIIDINPHQQETVYTTYDMKTQKAIDITSLPPLIMAPNGQVLRRDIPSVN
>A0A084CMM5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Photodesmus blepharus|TrEMBL
MFNLLGSSIKLLQITDTHLFARANGNLLSIKTLDSFRAVLDAIVENDIQFDIILATGDIS
QDHSAKSYQRFVDGVSVLKQPCLWLPGNHDDKLSMWSGVPSKRIFNLEHVLLSEHWQIIM
LDSQVIGVPYGYLRRRQIELLDRKLSQYHNYHTLVLLHHHPLLVGSIWLDRHSLKDSKKF
WKVIDKYDTVRVVLCGHVHQNMDQYFNNVRVLSTPSTCVQFKPNSNNFALDKLSPGWREL
ELHTDGSISTKVQRLGNGCFLPSFDEHGY
>A0A447SQA6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Avibacterium volantium|TrEMBL
MVDTYTYPTDNDVVRLVQITDPHLFKDENGELLGINTQASFNQVLSEIKQSDFDYELVLA
TGDLVQDSSSEGYLRFCETVQCLEKMVFWIPGNHDFQPKMFDILNHNNGNINPLKHLLIG
EHWQILMLDSQVFGVPHGQLGQYQIDWLLSKLKDYPERYSLVVLHHHILSTNSAWLDQHN
LRNALDLAYALSPFNNVKGILYGHIHQAVDSEWKGYKVMATPSTCIQFKPDSNSFALDTL
QPGWREIELYNDGRIETRVKRIQQATFLPNMLGEGY
>A0A7J7X6I9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rhinolophus ferrumequinum|TrEMBL
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQS
ERARTPEGDGMSRPTTLPLTTLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVL
HATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVR
NNFTVLTNLHGTSNKRSPATSQPPVSRVNLQDKKTEL
>B1AWD1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus musculus|TrEMBL
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQ
KDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIF
NVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAAD
VAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDES
VLENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMV
ETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKE
RERGMEISPMCDKHTASVEKSQVSTLRLFSMFLMSSTNCSFL
>A0A3Q2NXD1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Fundulus heteroclitus|TrEMBL
SPRSLKDGMLNRELSHLSEMSRSGNQVSEYISSTFMDKQNEVEIPSPTLKDKSMSHISGV
RKLSHSSSLSSASMPRFGVNTDHEEELAKELEDLNKWSFNIFRVAEFSNNRPLSCIMYAI
FQAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKL
LHQENCDIFQNLTKRQRQSLRKLVIDMVLATDMSKHMTLMADLKTMVETKKVTSSGVLLL
DHYTERLQVLKNMVHCADLSNPTKPLPLYRQWTERIMEEFFRQGDRERERGMEISAMCDK
HTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEENREWYLNTMPQSPSPPPDR
HLQHDRFQFELTLDELEYNNHNNMYRRKNGEEDKAPKKNAV
>A0A4P6WS49|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter arsenatis|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRIFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A099LQE0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio navarrensis|TrEMBL
MQHTTSDTSSIKLLQITDTHLFATDEGSLLSVKTLQSFQAVVEQVIQRQVAFDYVLATGD
ISQDHSAHSYQHFAKGIAPLQKPCFWLPGNHDYKPNMSSVLPSSQITAPEYVALGEHWQM
VLLDSQVVGVPHGRLSDSQLALLEEKLASNPSKHTLILLHHHPLLVGSAWLDQHTLKDAE
VFWEIVYRYPNVKGIVCGHVHQDMNRMHHGIRVMATPSTCVQFKPNSDDFALDNVSPGWR
ELQLHADGEITTQVQRLSAGSFLPDFTSSGY
>A0A6M2A7S0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chlamydiae bacterium|TrEMBL
MYPRGVSYVIDFLSVASIVGIWPRFIEPRLLKETTLDWPLEERHAHLDGLTIAHLTDLHF
HKGVSQKFLDKILRKIHRASPDLILFTGDFLCYAQLDEGERLKKFLQQLEAPLGSFCSLG
NHDYASYISRNKEGVYDLLPPPNPLKGVLRGVKILFSTPSISYSVSDRAKAVGLNEPLCS
LLDKTPFTLLENTTTTLPKGLNITGLGDLALGRCSPEIAFANYDPNHPGLVLSHNPDSTP
SLLNYPGDWILAGHTHGEQIHLPWPKWGRKLSQKLTLLQNREYTRGLFDLGGKKLYVNRG
LGGHKPFRFCSPPEICFIKARK
>A0A3Q9JIR6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microbacterium oxydans|TrEMBL
MSRATGRLTVLHLSDVHAMSSGLLYDTVDGFARLRAVGAYLRDAGITPEAVVITGDLVQR
GNADAYPALREAFDELAEIAGVPVLTAIGNHDEPEAARVLRGHEQTHHRVHIVDELRFII
LDSSRGELGVDQRAWLRDVLRTPHGLGTVVAVHHAPLGSPLPTLAKAGLRDADGFLDAMA
GSDVRAVLAGHFHHPLSATLRGIPVFVGPSLAYHQVMDAGPNRVSGHDLAMFSLVHLLPG
GVAVTNVGLDSPAPIFSSVIST
>A0A4U5UI67|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Collichthys lucidus|TrEMBL
MMAERVTRMKRMMILRLVMISESSFDVENGPSASCSPLDPQASPGSGLVLHTNFPGHNQR
RESFLYRSDSDYDLSPKSMSRNSSIASELHGDDLIVTPFAQVLASLRSVRNNFTVLTNVQ
CASSK
>A0A1B8YHQ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus namnaonensis|TrEMBL
MESQFELPVVEGTTAKILQITDTHLFAGKEDTLLGINTYRSYQAVLDAILKQNADIDLIV
ATGDLVQDQSLEAYRHFAEGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGK
RWQLLMLDSQVQGVPHGELSEYQLEWMKKCLDKYPERYTVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQGYSRVKAMLCGHIHQEMDMDWNGIRMMATPSTSVQFKPHCTNFTLDTVA
PGWRYLELSVADNGEFGLTTQVHRLESNEFCPDLDSDGY
>A0A7Y3Q937|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. 1-2|TrEMBL
MQSSSDSIKLLQITDTHLFAADEGSLLSVKTADSFNAVVADVLRRNVTFDYILATGDISQ
DHSAESYQRFAEGIEPLEKDCFWLPGNHDYKPNMGSVLPSQQIKAAEHVLLGAHWQLVLL
DSQVVGVPHGRLSDQQLALLEEKLAEHPERHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFDNVKGILCGHVHQDMNVLHNGIRVMATPSTCVQFKPNSDDFALDTTSPGWRELQ
LHACGDITTQVGRLPDGQFQPDFSSNGY
>H0KFL7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aggregatibacter actinomycetemcomitans RhAA1|TrEMBL
MLNTYKYDTRQEVFRVIQITDPHLFKDATGELLGVNTQESFSQVLSEIRQQAYDYDLVLA
TGDLVQDSSEEGYLRFCESVKSLEKTVFWIPGNHDFQPKMFDILKRDNICDKKHILLGEN
WQILLLDSQIFGVPHGQLGQYQLDWLMAKLKEHPQRYSLVVLHHHILSTHSAWLDQHNLR
NAHELAYTLAPFNNVKGILYGHIHQQVDGEWNGYKIMATPSTGIQFKPDSNTFALDTAQP
GWREIELYADGRIETRVKRIKHKTFLPNLQEEGY
>A0A5E4ZAY6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea iniqua|TrEMBL
MSQTSQASRAPSGATDGPAHRQGKSSRRTLPARPRWLMLAIIALLHAYIGWRLLTPLPVG
MGWKVIGALWLIASTVLIPLGLMSRALQREPLATLLNWSGMMAVGIFSSLFVLTLLRDVV
LGVAMAFSVLDAQLVTRSAVIVLLLTAASTVLGFYNARRLARVVDVDIPIANLPPELKGF
TIVQLSDIHVSSTIRRRYIDAIVDATNELKPDLVAITGDLVDGSVPALRDHIAPLGRLES
RHGTYVCTGNHEYYSGAPAWVEELRRIGLTVLENQHVVLDHEGAALTVAGVTDFGAHHFD
PEKRSDPQAAVAGSPEDVPRVLLAHQPRSAPAAAEAGIDLQLSGHTHGGQFWPWMYFVPL
QQPFVHGLHRLGRLAIYVSRGTGYWGPPKRFGAPSEITRIRLVPGNA
>A0A6L9FI04|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. V39_P1S14PM300|TrEMBL
MNVSSSSTDQRIKLLQITDTHLFAPEDGSLLSVNTAESFHAVVAAILERQVGFDAILATG
DISQDHSRESYEKFERGIQPLSQPCFWLPGNHDYKPSMGAILPSQQIQTAEHVLLGEHWQ
MILLDSQVVGVPHGRLSDAQLTLLDNQLSAHPDRYTLVLLHHHPLLVGSAWLDQHTLKDS
EAFWEIVDKHSNVRAVLCGHIHQEMDLQRGDVRVMATPSTCVQFKPRSNDFALDRQSPGW
RELELCQDGTLHTQVQRLPEGHFLPDFSASGY
>A0A5E4K8D3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MVLENLRGHYIRITVGITALVLLMACGAGAAHYAYAANRESGSVSVIGAATNTVTASVNA
GSSPSAFGQFIGELTPTPTPMTALIITSITVLSSIVIPAGKTQAFAAKDQNGNDITARVT
WNSSDSSVGTIDQNTGVFTALKAGGTVLTATSGSVSGSAIVNVVEDFSFAHLTDVHIGYY
PWQDARENMKSSVERFADTMQAVKSAHPDRVLITGDLVQYDNKDFFTAFKNILKGISIPV
NTTPGNHDRRKVLTGDNLSDYNTIINSRNNPSNRNDDNYSFDFKGYRFIGLDSGADNITY
SVPEPNSNGLADDQIRRLRSSEFNNSAPKIVFMHHPVMTFYAGNKVPSDGCPGGNDWTII
NNRCNFEDYTKESNVQLVLTGHTHNDAILDLNGNLATTDNPGRPLFIQTRSATLDENNLV
YGYRIIKVKDGKASPSNPYYSDPTPRFYRVTGVLQPVHVEVALRFGLYAYDHNGDYTGMK
ADGSDLALGIPDSYYTGDYGGSTTPQVIVGYYTNNGEKIKEFRVCPLGSSSGCIPLASRV
SNTARYAKPLPAIQNTSSENMSFNMSIEDRNETSKIEINFYNVNVTGSSTAIVNISDPTN
YHMDVDIKGDGTIVRTVYPDSISTTQIPIPTGLISRYDSNGDGRIERSEAVHGVMDYFSG
IITKQDAIAVVMAYFIG
>A0A5E4JH71|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MNENFIVLTFKDGIRKVNKLELTQDPYLISDFHLSHKNIILYSNRPFKSIEEMNAALIHN
WNSVIEETDIVIFVGDLFLGHKKELERWLSLLKGNIIFIKGNHDSKSFNAPKELIIVFQG
QQFFVTHNPANKPLDWQGWMIHGHTHNSNTNKYPLINKANKTINASCELMNYTPIRLSAL
LKKIEANDS
>A0A5E4KUL8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MRLLALSDLHGDYSHIEALLDKAGDIDAVLIAGDITNFGPDERALDLLGMFREPVLAVPG
NCDNPSLLKMLDENAISLHNSSYTLNDLTFVGLGGSNPTPFNTPFELSEKKIGEYIGTLL
ANLKGRIILLSHAPPRNTLDKVPRGNAGSEALARYLGRFDLIVCGHIHEARGSVKVNGTL
VVNLGVASKGQAALITINEEIKIELIDA
>A0A3R8WFE9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. s199|TrEMBL
MSAAPLTAVEDSVLLVQLTDSHLFAEAGGKLLGMDTAESLERVVDLVLEEQPKVDLVLAT
GDLSQDGSVASYRRFRQLAERIPAPFRWCPGNHDELAAMREATRDSEMMLPVLDIGGWRV
VMLDTLVSGSVFGFLDAEQLVLLERALAEVPQRHVLVCLHHHPVTIGSRWMDTIGLHNRE
QLFEVIDRHSNVRALLWGHIHQEFDDRRGAVRLLASPSTGVQFAPGSEDFQVDSLAPGYR
WLRLHADGGLDTGVSRVSGIDFEIDYSIKGY
>A0A8C1V7P8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyprinus carpio|TrEMBL
MDRTYAVDTGHRPGLKKSRMSWPSSFQGFRRFDVDNGTSSGRSPLDPMTSPGSGLILQAN
FVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDMNNHLPRPGLVSRRSEPVISGNHGDD
LIVTPFAQVLASLRTVRNNFATLTNLQQDRTSNKRSPMCNQPPLTKASFTGEMVSLWVLY
YFRNLIVITVNCVSHFLFALHLIQLFMEI
>A0A7H4M5X4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella michiganensis|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIRASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFTAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQVLLMDSQVFGVPHGELSDFQLEWLEQKLTEVPQRYTLLLLHHHPMPSGCSWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A2K9PDM0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter freundii complex sp. CFNIH2|TrEMBL
MESLLNLSLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEGQEYDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKCVMVGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLAAAPERHTLLLLHHHPMPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDSIG
PGWRTLELFADGTLKTDVCRLQGTEFRPDTASEGY
>A0A1A8UNK8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothobranchius furzeri|TrEMBL
MSSNELSVEMDSCIRTFKEHMHLELEPPKMPGVMGGKRGATSPKLSPRSSPRLFRKLMVN
KSIRQRRRFTVAHTCFDVENGPSASCSPLDPQASPGSGLVLHTNFPGHNQRRESFLYRSD
SDYELSPKSMSRNSSIASELHGDDLIVTPFAQVLASLRSVRNNFTILTNVQCPSSKRSPA
ATTQPPITKVCLPDEAYQKLAMETMEELDWCLDQLETIQTYRS
>A0A1I6DUZ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. kpr-6|TrEMBL
MESLLNLVLAGEANVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHAEQRNCDLIV
ATGDLAQDHTAAAYQHFAEGIASFHAPCVWLPGNHDFQPAMYGALQEAGISPSKRVFAGE
HWQILLLDSQVFGVPHGELSEFQLEWLEQKLSDAPDRHTLLLLHHHPLPAGCGWLDQHSL
RNAQELDNVLVRFPRVKHLLCGHIHQEQDLNWNGRRMLATPSTCVQFKPHCSNFTLDTIA
PGWRWLELCADGTVHTEVCRLQSTQFNPDTASEGY
>R8WMH7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. KTE151|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRAKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A7K0CUN0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nocardia macrotermitis|TrEMBL
MNTLTIIQLTDTHIRAAGELLHGCVDTMANLNVVLDGLRNGTRIDALVLSGDLTDNGSPE
AYRRLAAAVEPVAAELGAAVVYAMGNHDERVAFGVELLGMDAEGLDPEQPHDSVVMVEGL
RIVALDSSSQGCHNGHLDADQLEWLAAQLSTPAPRGTLLVLHHPPIPSANPAAEVLKLQR
AEELAAVVVGTDVRMIVCGHNHFTAASSLAGIPVWLGPAVAYRLDPMAPEGRHRGISGFG
YSRIDVVGSAFVATAVEATPVSVVYDRPQSEILAQLAASAAEQQ
>A0A853I4T0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Endozoicomonas sp. SM1973|TrEMBL
MSVNTASQVALRILQVTDSHLYASQQGQLLGVNTQDSLKAVLIAFSQLQREVDLMLVTGD
ISQDGSPESYQRFVDCTASYEIPQRWIAGNHDEYLLMQQLYKSKPCLNKAFVAQDWQVLM
LNSNVPGKVYGELADEELNYLKQQLDNSTAKYTMICLHHHTLPVGCDWLDNIGLRNADKF
NQLIDQYDQVKLVLCGHIHQELDRQDYHARYLGSPSTCVQFARHSSEFKLDNLAPGFRLI
NLMENGDIVTSVHRAEQFNFQIDEDAIGY
>A0A2S6US90|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alphaproteobacteria bacterium MarineAlpha3_Bin5|TrEMBL
MKFIHITDPHLTKSNQLFNIKVTNQLVTAVDHITKNHSDAELCVITGDLTHWAEPEAYTD
LQSILQQLPMPWHILIGNHDNRQLIRKIFPNIPVDENGFLQYIVPTSAGDFIVLDTIDEG
FHHGIICEKRLAWLQRHLKEINNKNDVYLFMHHAPMSTEISGLDHILLKNADRFFQLIKT
FRSIKHIFFGHLHRSFHGNWHNISFSTVKGTAHQVAADFTKNAPLSGSRELPAYAVVFIR
KDGVFIHDISYLEENTKFDYE
>A0A485NZI3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lynx pardinus|TrEMBL
MSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPIPSNKRSPLGGPT
PVCKATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSE
MSRSGNQVSEYISTTFLDKQNEVEIPSPTMKDREKQPAPRQRPSQQPPPPGPQFQPMSQI
TGVKKLMHSSSLSDSSIPRFGVKTNQEELLAQELENLNKWGLNIFCVSEYAGGRSLSCIM
YTIFQERDLLKKFRIPVDTMVTYMLTLEDHYHPDVAYHNSLHAADVLQSTHVLLATPALD
AVFTDLEILAALFAAAIHDVDHPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXP
ADSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMS
KHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTD
RIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQE
ILDTLEDNRDWYYSAIRQSPSPPPEEEPRGPGHPPPPDKFQFELTLEEEDEEEVSTAPGA
FTVQGLSVAQDASPAEELLEVDGQDMPTEVKVQEPCCTQQADSAGSVAAGKDKATSPDAS
VDAVGRSSPLALSAGSPLPPALRTPPPPEDTPGLPGLPSTAAEAGAQKEHQAAKRACSAC
TGTSGEDPPPLPAPGGWGSAGGPT
>A0A0H3GYJ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pneumoniae subsp. pneumoniae (strain HS11286)|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A494WUX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clostridium scindens (strain ATCC 35704 / DSM 5676 / VPI 13733 / 19)|TrEMBL
MIAVFLAPVYLILNAYIFRWLIRFMGACTHHFQKTWVRLIVLAFYGFLALSILLAFFWPA
RWLIYISNIWFGTLCYILLTILVADGIRLIAKLIVKRMKKREWKESRRLFVASGTLCISL
ILSLSVYGYLNARQIHTTDYSVTIKKSCKDLDSMKVVLVADLHLGYSVGNAQMSQMVRKI
NAQDPDLVVIAGDIFDNNYDALKNPDKIARTLRGIKSNYGVYACYGNHDIQEKILAGFTF
SHDKKKMSDPRMDQFLKDANIQFLHDEGVLIDDSFYLFGRADKERPGRGISKRLSPKELT
KEMDTDKPILVIDHEPDQLQELADAGVDIDLCGHTHDGQMFPGNLTIKLLWENPCGYLKK
DQMHNIVTSGVGVFGPNMRVGTKSEICVIDVGFQ
>A0A2S9XDB6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enhygromyxa salina|TrEMBL
MPVVLHFSDLHFGPHSRFAGQDPAEVGKRFFAQVREACVDKGLGEVELVVVTGDLTESAR
KQEFESARRFFEALVGELGLDRGRFCFVPGNHDVSWAHCKRVRINQEIEEFDDEELERRL
HIEKMGPWNGFLADFYGAGEDPATRRSLGQGAFVHDHRDLRVSVAALDSCARETDRHHGG
FIAEAQAQALMSEWRREGRRAWIKLLAVHHNPVADCEDNLREWVGWLGDQAEAKTLGKDA
VLHFAADATGFEGRERLHAIAEDTQAQLVLHGHVHAAGHAPWSWRRGIKGQTQVVGAGSC
GLLEHKLPGEQPVMFQLLVLDPAAHELNILRRVWEPRARAAGSVELGTFVDDPAIPRGGL
VLDLGFPEGVMSPRPRPSSGPQVDRSFLGEYRMRLCGRHRIWELGAVHLGARRPATPALD
DMYVPLRLGAHQELDEVKPGGEVITPYRLLQRHRNLLIRGAAGSGKTTWMRWSFRRLLER
EDALPILIELRELARLWSQPGATGRQRNFDWWLGQWVERFVGGGWADALRAALTSKTGPR
PVLMVDGWDELGDLGREFREQFDGFLAAHPRVLAIATSRPYGEQVPEHDDRFEAVEVQPL
SDAEMGELVRLFFAKVYEGSEAEVAEEVERFVRALDAAEQAKSLGRTPLLLVMMLIIGRG
RPLPDRRHKLYEFCIEQLLDAHPGKRVQDGAQVASWQWAPADFDSRLRAVAKLALWMHEN
RGSARAGRLAVAKREALAAQLPRAWSTSERHGFLAWLVASSGLMVDFSDEALSFAHLGFQ
EYLAAWQLEVDCEGAPARIELCRRLARDVSWWETLRLWSALVEGRSLARLEPVLVDLLEA
GDVEYWLAGAIHADGVGAGVFDRWLELLPRAVLPLGEWSAATAAAAWRTSRQTERRARIA
ERLRGEVQDASWLDWWRLARWWRRAELDGYLNWPAEDTPAGIIVRTTEKLKVSREQVAWG
RIWMASSPLWCGAQLPLLALRLWPNRRMWIACVLQDRLGSRGPVDLAELERWRWSRLRGR
SVGAVLPDCTRRYVERVVEFGTVERELWLALEQARYVASFEVGNVTSVDRDRVRPVTLAR
ELGDAHRAANALARDSANRAAQWGDCLFDEDLAGQSLGFVGVRTMFAQALDDEPLVRLLS
KACRLSLANAAPDDELHVLCASFDGDPLWPALARHLARASSAEDRRLLEELAAHPERREG
VVGLGLEYWVRGDVLLPDGSQRTLEQLGEALPLLDEVPLELDISELLDSAL
>A0A517E0P2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sporomusa termitida|TrEMBL
MQHGPSIYGILFILALFAGLTWLGVRLLPKWHPVYAGKPVRYGYWLATILSIGILFCSRW
LRTAGSLAGEGVRYASYAAYVWLFGLLFMLVVLLAGYAVRLLVRKFSRPQTGHLATEPAA
GGVPVPGRLTRRQFLQGAVAVVPAVPLAVTAYGVIGGDTNIVVNRYTLAFPQLLPALDGY
VIAQISDTHIGSFFGMDKLDRVLAMVKQEKPQLLTLTGDLVDDLDLLSPTMARLTAFHSE
LSHGIFYCWGNHEYFRDIGRIRQALYASPVTVLENRSQAIGNGLYLAGVDYPWGRNKAEQ
EAKRRDFFAQAVRTIPAEAFTVLLAHHPDFLDNAFAANVPLALAGHTHGGQVSVFGVSLL
PVQYRYMRGLFRQHGSYGYVSAGTGHWMPLRIGCPAEVSLFTLQRGGS
>A0A1J4QEV9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oceanisphaera psychrotolerans|TrEMBL
MNQASTLDTTELSPHRADGVVELLQITDTHLFADKDTDLLGIASWHSCQAVVDAILEDQK
PRDMVLATGDLSQDHSAGSYRRFAELMSRLAPPVFWLPGNHDDAPVMQAELDQAGISDTK
HLLCGQWQILLLDTQIPGATHGELSASQLALLEQAIAGYPDHHLLVAVHHQAVPVGCAWL
DQHNLRNADAFRAILARHRAQRVVLFGHVHQGFDQVHDGVRYLASPSTCIQFKPLSDDFA
LEHTSPGWRALSLYPDGRLSTQVWRLPPDTFVPDFSAKGY
>A0A553QH07|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Danionella translucida|TrEMBL
EKIENEPPEHFVAGNHNHTLFCLSFRSYDGENGPSPGRSPMDSQASPGLVLHPSFPQSQR
RESFLYRSDSDYDMSPKTMSRNSSINSEGHAEDLIVTPFAQEVTSDQSTHSSPSNALSAS
HKETYQQLARETLEELDWCLDQLETIQTHRSVSEMASNKVSLNYLTVALVAPSRVL
>A0A182UG75|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles melas|TrEMBL
LALTPEEEPLDSCPRLVSDLKFPNLLPPNPVIKILIAFCKNDPVFEALVNASHRLSLEPT
FVKSAESAIDAFQNPSSGGHHIIIVDARYPRTIEAEALGRSIRNSKGSQHTTMVAVVKKS
VFEKDDTAVISLLDVGYNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQALYTALHR
SREAVIITDDTLRAQYANRASERVLNMKLDEIVGRSLSDLVTADISNILSHTSRYKDYDG
YLTTRRKSQESSQIHVRAVPVSCIGRNPTHLVLILESSSSALVSTNAIGEALQTLPQGKE
VPRGSLHSIRRGSFDVRSIASDGLRRTSLAKLSSLPLEAPITKVLSLLAQVQENCSLDEA
KLLDRVMEFLKREGLYSPQMKEIRTEDPVATDLIGALLTQGPTNILSSRRSSNDSIIRGG
GRPSTGSIVFNKTKESSQLSDLLQTALDWDFEIFKLEDLTEKRPLVCLGLELFRRFDVYN
TFNCDEMTFKLWLIEMEKHYHSENTYHNSTHAADVMQATAVYLQQLSNRELKIMDRMDEA
TALIAAATHDIDHPGRSSAFLCNSDNTLALLYNDICVLESHHAATTFRLTLGDDKINIFK
HLDRDMYKLARSIIVDMILATEMTRHFEHLAKFVSVFGTDVESKDPLPPDNDDNQILVRR
MLIKCADVSNPTRPLKFCVEWARRIAEEYFMQTDEEKRKNLPIVMPMFDRTTCSISKSQI
GFIEYIIHDMMDAWNSFIEMPEIIRYMEFNYSQWKLFEEQGINTLSDIKRKQMSLTEDTA
SSISLEEKF
>A0A5E7HYB9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPRVSTLTTADPALLVQLSDSHLFAEADGTLLGMNTRDSLQKVIELVRLQQPRIDLIVAS
GDISQDGTLESYQQFRDLTRQLDASARWIPGNHDEPRIMAEAAVQSALLDPVVDIGNWRV
TLLDSAVPGSVPGYLEDEQLQLLARALSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPE
ALFSVLDRFPQVRAVLWGHVHQEIDRERNGVRLIASPSTCIQFEPGSDDFKVGDQAPGYR
WLRLLPDGELETGVERVTGFAFQVDYGSNGY
>A0A0X4EUU8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter genomosp. O|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRVCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLTGAQFRPDTASEGY
>A0A427LML2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter soli|TrEMBL
MFQVAPFSSQAHVIIQITDTHLLEDPQHEFVGINPEQSFHQVIAHIRAHYPKIDAIIHTG
DLAQTPTAVTYARYLDYMQTLGIPFFHVPGNHDDPAHFPFHASSSQDISIVAMGQWHLVL
LNSAVVGKVDGWISDHQLMQLQQHLQQHPNVSMILACHHHPFEMQSKWIDQHKLKNTATL
LDVIHAHPQVKAVLCGHVHQESSHRWEHVEFLSSPSTSVQFKPRSDDFAFDALPSGYRVL
KLQANGEFESHIHRIEKMLQNINTEISGY
>A0A5X0ES18|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Duisburg|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A4W3HH27|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Callorhinchus milii|TrEMBL
EERKRGREGEESCSLVFLRSFELENGASGGRSPLDTQPSPGSALVLQTTVPSQGQRRESF
LYRSDSDYELSPKSMSRNSSIASEMHGDDLIVTPFAQVLASLRSIRSNFSLLTNVQGATG
RYLPQCWGAVLGGRSAGGWGSAGGGAVLGGSAEWEHWW
>A0A085U3G3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia ruckeri|TrEMBL
MESLFELPMASGARVRILQITDTHLFAGEDETLLGVNTGRSYRAVLDAVIAEKHPYDLIV
ATGDLAQDHSVAAYQHFAKGIARLPAPCVWLPGNHDFQPAMVDVLAEANIAPSKQVLVGD
NWQVILLDSQVFGVPYGELSEHQLEWMERCLMAYPQRYTLILLHHHPMTSGCTWLDQHSL
RNAHVLAAVLTRYPRVTTLLCGHIHQELDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGTLETEVRRLDSDEFNPNMDADGY
>A0A4Y6I962|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. SNU WT4|TrEMBL
MQKDATTYDIIEGQSIRLVQITDPHLFSDPQGQLLGVNTRASLASVLQLVHDNHQNVDCI
LATGDISQDYSAQSYQAFAAMMSTHTVPCHYLPGNHDDIHTMNLHLQGEKLSGDKQILVG
NWQILMLDSTVRGKPGGLLSDAELSFIERSVAQEPQRHCLLVMHHNPILTGAAWLDQHCL
ANGNEVLKSVSQLANVRGILWGHVHQQIDKTYPGATGDIHLMATPSTCIQFTPKSDFFAL
DNLQPGYRLLDLHADGSMSTHVYRVPGKTFFPDESAGGY
>A0A7G2JSH3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia grimesii|TrEMBL
MESLFKLTVASGARVRILQITDTHLFAGENETLLGINTYRSYHAVLDAIKAQQRDFDLVV
ATGDLAQDHSLAAYQHFAEGIARLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKHVLVGD
HWQVLLLDSQVFGVPHGELSEYQLEWMERCLQAYPDRYTLMLLHHHPLPSGCTWLDQHSL
RNPHMLGAILLRYPKVNTLLCGHIHQELDLEWQGRRLLASPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRIETQVFRLENDDFRPDMDSDGY
>A0A729Q8B4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. houtenae serovar 18:z36,z38:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A395L3L8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ensifer sp. M14|TrEMBL
MLKRRQPSIAVIADAHFHDLEGDFDFPGMTIDGQRMMVRSWAETRQSTRVFNESAKALSV
ALDEVRDRGIRHVVLLGDYTDDGQRQTTASLRRILDRHASEYGTAFYALPGNHDIFGPSG
RNHTKEFLDQEGAGVWVASDPASTTEGAIVTPRMYCEGYPSGLGPMAAYGYFRKSEYLHW
ETPFGLSDDVESRRYEVASPDGRNRYALMDASYLVEPEPGLWLLMMDANVFEPRDGTFES
GEEAAFIDSTAAGWNAMLRLKPFIVTWIADVCARAKVLGKTVLAFSHYPALDPFDGATGA
ERVLFGETNIARRTPRQTVTDALLGAGLAVHFSGHLHVEGVTRRGRGGRQLTNVAVPSLV
AYPPAFKVIEPTEDGITVDTVELQTMAVDPRLPQAYRRETARLEEPDDAAFDAEDYGAFL
RAHKVALVRHRYFPKEWPQDVVSRVSGATIADVSAELVDAEVAVAVLHALAKTSGIATEQ
LAACRMIDIIADWYCLRQAAHLALPAIAPERLGLYRALAERFGREPQEGWDGSIAGFLSI
FLGAFAAFIDRAENGARQIEITLQREAKEVACP
>A0A5B0C5E5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. ANT_H4|TrEMBL
MPSVSALNPDASALLVQLSDSHLFAETDSTLLGMNSRDSLQRVIDLVRAQQPQIDLLLAT
GDLSQDGTLESYQQFRDMTRQVSAPARWIPGNHDEPHIMLQATVNSALLEPVVDVGNWRV
TLLDSAVPGSVPGYLQDRQLQLLARSLSEAPSRHHLVCLHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVKALLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEEAPGYR
WLRLHADGRLETGVERVEGFEFQVDYGSNGY
>W0HMT6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Sodalis pierantonius str. SOPE|TrEMBL
MESLLKLLVARGANIRILQITDTHLFAGEDETLLGVNTLCSYSAVLKAVQAEQRHFDLVV
ATGDLAQDHSPQAYRHFATRIARLPAPCVWLPGNHDFQPAMVDVLAECGISCAKQVLIGD
EWQLLLLDSQVYGVPHGELSDYQLEWLAQALAGQPERHTLLLLHHHPFPSGCIWLDQHSL
RNAHMLAEVLQPHQRVKTLLCGHIHQELDVDWLGRRVLATPSTCVQFKPHCTNFTIDTLG
PGWRYLDLLPGGAVQTEVRRLDGIEHMPDTDYEGY
>A0A6S5KT44|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYNSLHEAGISPAKCVFAGD
QWQILLLDSQVFGVPHGELSEFQLDWLENKLAAEPSRHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLVKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLSGAKFRPDTASEGY
>A0A6S5JWQ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAEHRDCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
KWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLTKFPRVKHLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLAGAQFRPDTASEGY
>A0A144U0B8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLNAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMFSSLQNAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPLVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLTGAKFRPDTASEGY
>A0A6A7G9K3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hirondellea gigas|TrEMBL
QAVFAALDACRDAVHITDHNHRIQYINKPCETLLGYSSQDVIGKSIWEVHGSDHHRQELR
GLDLRKQQTDTSSRPTDVKTENRDSKTEGKPTENKTDNRATELSSRISEEKSEADEMKVD
KSKQQIMDSYTSAGVDIGKPPHKVLERQESKVGLDISEAINLQLRRGREWEGVVMCRRKS
GDLLHLPSRVMPVPTRRNSGNSSSAGLSSGDYIVYSSSGSSSATVPAAHSGVTYSDRHHT
DIYHNRGSIKSLRKTSYDIRSLNSDGSQNTARRQSIVKLHSVTIEAPITRVISIITSAQE
NSPVYVSQALEKVLEILRSKELYSPQLVANTENIKPVPADAVATDLLGALLSQHSPTPLY
PGRRSSNDTSGSKPQVCRPNLSNLSQAAATDVTELLTTDNSWAFDIIRLEQLTEKRPLVS
LGLSLMCQMNVPATLHCDEQTLQNWLTLIEANYHADNSYHNSTHAADVLHATAYFLQRPR
IAGLLDPLDVAAALVAAAVHDVDHPGKNSAFLCNTNNELAVLYNDTSVLESHHSALSFKL
TNTDARVNIYKGLDRDTYKEVRKSVLDMVLATDMTKHFEHLSKFVNMLDKCSMTKEDCDQ
YETVGETLNVDQLSVPENQQILRRMLIKCADVSNPLRPRHLCIDWGYRIANEYFSQTEEE
KRRNLPIVMPQFDRSTCSIPKSQIGFIDFFISDMFEAWDTLADIPDCMSYLRSNYQYWQE
MEERDKLASSASGSRPASGVSTTPVPEEDEGIQGLKLDGTITEQEG
>A0A1Q9P8M7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Thorarchaeota archaeon (strain AB_25)|TrEMBL
MNLSPVKIAAVADVHSPRFLNEFKTALSVCERPDLFLFAGDMINRGKADEYINVLDTLES
QFGSDFPIVACFGNEDPLDLRDELLSMTKDRLTFLDEKSLTLNLSDSRITIVGMSTVSME
LRNPQTIQTIFEERARQLSQLLQDASRSSDYVILLMHFSPLLETNPAEFSWWVSRAIENF
APNLIIHGHIHNSTRNIIEIGATTIRNVALPAIGSITELGI
>A0A420XF58|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Otariodibacter oris|TrEMBL
MKGAYELPSASPIVRILQITDPHLFATPDGQLLGVPTVKSFQAVLDAIQKEAFDYEIILA
TGDLVQDHNREAYHRFGQMVKQLKKPLFWIEGNHDLQPQMSNALGIYAQIQPHRHILLSN
NWQVVLLDSHVFGKPGGKLSKSQLAWLAETLKNNAERYTLVVLHHNILPTNSAWLDQHSL
SNPEQLADVLSDFPNVKAILHGHIHQEVDKKWMDYRVLATPSTCIQFKPNCDKFTLDIKS
PGWRELNLMPNGVIKTVVKRLEDACFLPNFSATGY
>A0A6M1YT58|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Anoxychlamydiales bacterium|TrEMBL
MQIFAISDLHLSLSNPEKTMEDFGDIWKDYQKKIESNWKKTVTANDLVLVPGDISWAIKL
KDALIDLEWLHSLPGKKVIIRGNHDYWWPSFSKLKEAIPPSISFIQNNALSFDDIAIAGA
RLWDTKEYNFDEYINFVYNPKQKNDLEKDIQKDLSEKIFLREIERLKLSLEKLDTKAKTK
IVMTHYPPISADLKDSIVSKLLEKHNIDICIFGHLHNLKAEKKMFGQKNNIKYMLTSADY
INFNPIKLL
>A0A0E1T2J9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli 53638|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A3S9L8W0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella khirikhana|TrEMBL
MLKEAVEYSLTEGETARLVQITDPHLFASHEGQLLGVNTAQSLSAVLNTLNATHYPAHLM
LATGDISQDYTPESYRNFVDAIGFLGLPCHYLPGNHDDPRVMHLHMQGPRVFGQQRIFIG
NWQILMLDSTVRGKPGGHMGEVQFALIDEAIAAEPERHTLLVMHHNPILVECAWLDQHCM
DNGAAFLERVSQYPQVKGVLWGHVHQALDEFYPRDNAPLPLMATPSTCIQFKPKSPYFAL
DHLQPGYRLLELLHDGSIHTHVYRVPGNLFAPDHNSSGY
>A0A0U1HNX7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia rohdei|TrEMBL
MESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYKNFAEGISRLSAPCVWLPGNHDFQPAMVDALADAGIAPSKQVLVGE
NWQILLLDSQVFGVPYGELSEHQLEWMERCLVAHPERYTLVLLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPHVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPNGRLETEVRRLASNEFCPDMDSDGY
>A0A644TJR1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKKNVLRVMILVVVVLLGYLGVSSTVDHTKKAEGYYRIVLLSDTHLPTKTFNVKDKDKED
RIIAAKKKVIEDINNWQDVREIAVLGDVVGDTGTDKEYAYAKDFFSKLHKPISFIAGNHD
YIYQDNPSSSGRYVKGDAKSRLLKLDKFKKTFGLSRLFYEKKVAGYLLVFLSVDSLDSPY
LTQMSPEELSWLKDTLKKNSTVPTIIFFHAPLEGTLSNYNKNANKPSFIAQPAAEIAKII
ENNKQIVLWVSGHTHTPATNPSFASNINFYKGRLLNLHNSDMERTTIWTNSLFLYPNKIV
IRTFNHKTETWMKELERTIPIER
>A0A7W3BN13|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. RHBSTW-00271|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A8C3MBH6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Geospiza parvula|TrEMBL
CAPSCAHSQQVEEPAGPDWAPLSPQGHQGRVCWTQREGGTESPTNLAASPGLRSPRQPCP
LSPHSFDLENGPPGRGALDPQASPGAGLVLQGSFSHGQRRESFLYRSDSDYDLSPKAMSR
NSSIASDLHGEDMIVTPFAQVLASLRTVRSNLSHLQDRAGIK
>A0A8F9XQ47|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dickeya zeae|TrEMBL
MESLLTLPVASGARVRILQITDTHLFADEQGTLLGVNTNRSYQAVLNAIAAQQMNVDLIT
ATGDLAQDHTQDAYTHFAMGIRRLGAPCVWLPGNHDFQPAMVDVLARSGIAPSKHVLLGE
HWQVILLDSQVFGVPHGELSEYQLEWLDRSLQSQPERHTLLMLHHHPLSSGCTWLDQHSL
RNAHSLDALLSRFPRVRTVLCGHIHQEMDLDWNGRRLLATPSTCVQFKPHCTNFTIDNVA
PGWRYLELLPDGGMETRVCRLEGNEFLPDMDSEGY
>A0A6G1W6G0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas helleri|TrEMBL
MPNVSTLTTLDPVLLVQLTDSHLFADADGSLLGLKTAESLQRVIDLVRAEQPVVDLLLAT
GDLTQDATVEAYQRFRQMTDVLAAPARWLPGNHDDLIPMAEAAVQSRLLEPVIDIGNWRI
TLLNSSVAGKAHGYLEDDQLQRLAQALSEAPERHHLVCLHHHPVPIGCEWMNAISLHNAT
AFWTVVDRFPQVRAVLWGHVHQTFDQERNGVRLLATPSTCLQFEPGSTDFKVSTQAPGYR
WLRLLPDGDVQTGISRLADFTFKPDYSANNY
>A0A0G9F7H4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lactiplantibacillus plantarum|TrEMBL
MQYFTSDTHFYHADLLGDNDFAPRLFPDVETMNQAIVDHWNARVTDQDTVYHLGDVALYF
TRPAKLSYERVFALLAQLNGKIIFIKGNHDSRAFFKYLAAHDPQLNGQPKFEFHDVGVLI
KYDHRQYYMTHYPMMMGIVKQIINLHGHIHHYAVNVKENINVGVDTPEVDYLDHPVPFGT
PFSLAEIEQMVDGKAIDFAKRQ
>A0A4Z8Z5P3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Bareilly|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A3W0FCV1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Litchfield|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A564U1P6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Faecalibacterium prausnitzii|TrEMBL
MALFALGDTHLSLGGSKPMDVFPGWNGYVERLEANWRKLVKPEDTIVLAGDISWAMRLTD
TRRDFEFLQQLPGQKLIMKGNHDYWWTTANKMNTYLKAEGFDTLHILHNNSYSVEGYAIC
GTRGWLFDVGEPHDEKVMNREIGRLKMSLDAAEPGLEKLVFLHYPPVYTGTSAPEIVATL
KAYGIRTCYYGHLHGNAIRYAVQGDVDGIRYKLVSADGLRFCPYRIN
>A0A533QGK9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Accumulibacter sp|TrEMBL
MRIVQLSDLHLSSQPLYGVVDTLAALELALQRLATLPAPDLLLLSGDLTSAGRRDEYALL
RSLLAGLSVPCALLPGNHDDRDNLRTAFPEQAWAPPPLCCQRIDLAEGTLLLLDCIVPGE
EWGEVAARQIDWLESACPHRRPVLLALHHPPFCVGIAGMDRIRCRGDAPLAAWLARHEQV
EALLFGHVHRFVSTTFAGRPAIVAPSPAHQIALQDGQLAYTLEPGAFLLHDWRPGQRLCS
HYVPVVVSPTQCYGDG
>A0A3S4E9Z7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia odorifera|TrEMBL
MESLLKLPVASGAKVRILQITDTHLFAGENETLLGINTYRSYHAVLDAICAQQREYDLIV
ATGDLAQDHSLEAYRHFADGIAQLPAPCVWLPGNHDFQPAMVDALAAAGISPSKQVLLGD
GWQVILLDSQVFGVPHGELSEYQLEWLERCLQAYPERATLLLLHHHPLPSGCTWLDQHSL
RNPHMLDVVLQRYPKVNTLLCGHIHQDLDLAWHGRRVLASPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A157FEN7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter roggenkampii|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSAPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHPDGTLTTEVCRLTGAQFRPDTASEGY
>A0A1E7R515|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter qingfengensis|TrEMBL
MAKHLSKSHTSLAQQPIRILQISDAHLLNDKQGIFIGVNPYLSLQHVLRDAQQYAPYDCI
LSTGDLTQEPSPRSYQIYLDEVAQFNTPHIFIRGNHDDNQAFPETYDTENPDIQTIIIDH
WCLILLNSQTLEGSHGYLKAETLHQLQEVLTQYHEYHTLIAMHHHSLPVGCAWLDQQNLR
NAAEFLQCIHANPQIKAVINGHVHQATEQTISGVAFMSCPSTCVQFSPHSQDFSLDIQPP
GYRILELYSDGKIITKINRINKILGEIDHQLTHY
>A0A5Y2EAK8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Tennessee|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A3R9Z6H8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter baumannii|TrEMBL
MNFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIQQILKQHPEADAIIHT
GDLAQAPTPITYKRYINFMQTLGLPFFQTLGNHDNVDHFPLHNENHQQPVVVGLGNWRVI
MLNSAVKGKVDGHLSSEQLENLANLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFQNVKALVCGHVHQDSLNIWQGVEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLNNDGSFETKVFRLENFKTRINTDISGY
>A0A6M1YFV4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Anoxychlamydiales bacterium|TrEMBL
MIKIAQISDLHFSTFSLKIKDLFSKRLIGMVNLLINRKKSYIDKHLYKLPSLFRSLDLDY
VFISGDLTSTSLIKEFEKAKKFTSSFDKDLKFFIIPGNHDQYTKKAFQKDFFYNFFENKN
KLQTKSLKKDKIEILSLSDKWVSIGLDTTLATSLFSASGLFSKDLEKTLIEILDAIPKDK
NIILINHFPIIHIAPKRKHLKRRAVLLDIIKKHPNIKLYLHGHTHKLAVEKEDNLPFMIC
SGCSSHKKNGSFNLFEIENDKCKVINYKIKNNSWQKNKTWQLHF
>A0A0D7LGK5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter freundii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A3V8Z2F7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella oranienberg|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>E2QE58|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A6J1Q3X5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Temnothorax curvispinosus|TrEMBL
MQVAKLISQLATRIRKGPQDLSNYLLTTNVPSIVKILLVFSKDDPQLDILANTARRLGWS
VSVAKDAEKAIELFQNRAHELVIIDHRGHHAAEGDAICRAIRSSPVYHNSVIIALVKKSY
FMLDEKDHIVALNLLETGFSRALIECSHEGILINELVGIYTSSLLPRTQLAAAHALYLAL
DRCRDMVHVTNDKNIVQFLNKVSEKLLGYKTEEMMGRNLSEIVFYENSALMEQQLAKGRE
FEGNMNCKRKNNQMITINCRIIPFCITLKKPSHYIYVYDTTYLSENSAPISPASSPLHPP
LKTSILSNARKSSDVRSGVSEGRRRSSLQKLHTLQLEAPITKVITLLSNAVTDTTNPETA
AQIDKAIDILKTTELYVPHLKEDRAMYSDPVATDLVGALLASPRTAWESRRSSSDSARLS
TIKAIAYPANSRVQVKNFRGPQELMDILDNSLDWNFEIFKLEVLTEKRPLVFLGLTIMNL
YQVPATLHCDEKTLQNWLAIIEHSYNAENSYHNSTHAADVMQATARFMQSKRLKEILEPL
DEVAALIAAAAHDIDHPGRSSQFLCNANSRLAILYNDLSVLESHHAALTFKLSLSDDSVN
IFKNLDRDAYKLLRQNVIDMILATEMTKHFEHLAKFMNVCSARIGDGQETYSDSLDMSVV
LQPDNVILVKRMMIKCADVSNPTRPLKCCVEWARRIAEEYFNQTDEEKKLKMPVVMPMFD
RMTCSIPKSQIGFVDYIINDMIEAWDVFIDMPEIVGYMRHNYEKWKEYNEQGISTLQDVE
KLQQHPEMQIPRLS
>A0A6N9MTS4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLAKFPNVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADSRFQPDTASEGY
>A0A775U8R4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQEQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A0K4HZE1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPGRHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A2S3X0Z7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MLPPDQSRPVHVVQLTDAHLFADPAGSMLGLNTRDSLRHVVAQVRREQPLVDLLLCTGDL
SQDASVASYEAFRELTAPFAVPTRWLPGNHDEAQVMAQVAPELVQAVTDIGAWRVVMLNT
AVHGATHGFLQDDQLAVLEAALKEAGERHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDI
VEGYPQVRALLWGHVHQEWDEVREGRRLLATPSTCIQFAARSEGFQVSEEHPGYRWLRLH
ADGRLETGVERAVDFEVQLDFDSPGY
>A0A5W0QAT9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Typhimurium var. 5-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A8D4QK46|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENHEFDVILA
TGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNVAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLGKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAEFLPNMQEEGY
>A0A0M0QI20|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2R4HM06|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enteritidis|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A5J4SZK7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MIKLFPIISVLLLILGANFYVFYKLWVMLPEGIIGKVSLVTLGVAMLFSLVLAQAIGNNL
PLPVTAFMYRVGTSWFFIFIYLLILFLLLELIRVTGLFPVTRFMYRSWLGFGILTGVLTL
VLTGGYIVYLNKARVTLSLTVNKEMRAQGSLKIVAISDLHLGYGIGKNEFENWIKLINKE
NPDIVFIAGDAIDNSVYPLYEQGIAESFKQINAKYGVYASPGNHEYIAGISKSLAFLKEA
GVTVLRDSVAFIDDAFYVVGRDDRTNATRKSVKELTDTLDKSKLLILLDHQPYQLEQAGK
KRD
>A0A381GXR7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter koseri|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAGQHEYDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSDFQLEWLERKLADAPERHTLLLLHHHPLPSGCSWLDQHSL
RNAAELDSVLANYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIG
PGWRTLELYAGGSLETQVHRLPGTQFRPDTASEGY
>A0A8G2S1W2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas aeruginosa|TrEMBL
MSRHSNTPATDASVLLVQLSDSHLFAEDGARLLGMDTAHSLEKVVERVAREQPRIDLILA
TGDVSQDGSLDSYTRFRRLSAPLDAPLRWFAGNHDEREPMQRATEGSDLLEQVVDVGNWR
VVLLDSSIPGAVPGYLEDDQLELLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGY
RWLRLHDDGRLETGISRVDDVVFEVDYDTAGY
>A0A5S9PJZ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|BD1-7 clade bacterium|TrEMBL
MKYHALYAAMLATTVVLGGCNSDDGPQGERGLQGEQGIQGGQGAQGIQGAKGDQGEQGLQ
GDKGDQGVQGEKGEQGPQGEPGPAGTVDVKPEPPMDFQKIKLGVLPDTQGGPNGVALNQM
EAVLEHYKANGITHVIPVGDLTDNNTDLEYEQWSEMARRYSDSITFLPLMGNHDRVPGDN
YTWRRVMQEFIPRENIEHMPGRSYQTYAYTEGNTLMVQISDADQPYAYEWVETVLENRAE
HVKHVFVSTHKPFAGPYRGGIIHEYVVGHWHAAEENLFMTVDYNAWRDLMARHDVTYLSG
HDHQYSRSVIWAHSNTHDLTGDDGIVGAGNERRFFHHLVAGNASDKNYSVRYGEIEKAQD
MIMHRTATGEGGDPRIMELHTAEDLARDALAQPNRQVNATWFDIDGDSYAFSAFFENYTA
SDALLNGGAQWKLFDRYTRSTTRCDKVVYPVSTHPSSVHYNLFDVNFRTVECHSPSGEIA
RLVDGTNRVFNRVNSNLERTDKMFDTAESPEDKAAMSAYADRMRSYMKIEPDLEENVPGS
DEQFAIDGDNVFGQAHAKGFEVFERVVTEGEGDSAQDINQQVFIWYPHTYDMKKLVSLSW
QAKTDATASDVLVISGIQGHTGMFTNGNGAALDITMDPGFPGTTLTEAVTWMDEELQGAR
KQPIAYVDYLDAKSPNRTNAEMQWTLDADLRDGDVRADDYVVEFNAVEGTSTGNLQLGYM
VADQWQPLVAAECISAQAYKAEFMTALPDDISATDCPSNVAVGQSANGYWARLDFEGKFA
LINR
>A0A3B5MCC0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xiphophorus couchianus|TrEMBL
MLNRELSHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTLREREKPMCHISGVKKLTHS
SSLSNSTLPRFGVKTEHEEALARELDDLNKWGLNIFRVAEFSNNRPLSCIMFAIFQAVFT
DLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLHEENC
DIFQNLTKRQRQSLRKLVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLMLDHYTDR
IQVLRNMVHCADLSNPTKPLHVYRQWTERIMEEFFRQGDKERERGMEISPMCDKHTASVE
KSQVGFIDYIVHPLWETWGDLVHPDAQEILDTLEDNRDWYQSTIPQSPSPPSVCQEKELN
KCIDKFQFELTLEESSQNEISIETAFFREASVTFFSISVGNKA
>A0A2S6UQ89|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alphaproteobacteria bacterium MarineAlpha2_Bin1|TrEMBL
MFFSINHYNQIFHKKVPIMKKEFFIAQISDMHIVGNESLNILNNIQLEKTIKKINKFKPK
IDLIVATGDLTDNGYTNEYKVLQKIFSKSVPDVLMIPGNHDKRKNLIKIFSNQEYLLNNK
FFCYTVSNLPVFLIFLDTLVEGKPGGEICKERFLWLKERLFQNKDKPTIIFLHHPPFNCG
IWWMDAIGLKGRKELKKLIESYTNIEAILAGHIHRSIQKKWAGTFAHIAPSTAHQIELDI
SGNKFLHINDEPPAFSLHHWSADNGLTSHICYTEKSKSYVNSKIKDINKYREFFIKAKLE
LDKFEK
>A0A498QXK0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mycobacterium pseudokansasii|TrEMBL
MHRLRAAEHPRPEYVLLHISDTHLVGGDGPLYGAVDADGRLGELLGQLTHSGMCPDAIVF
TGDLADTGEAQAYRKLRAVVEPFAAELGAELIWVMGNHDDRAALRSFLLDEAPSMAPLDR
VHMIDGLRIITVDTSVPGYHHGELRRSQLSWLATQLATPAPHGTILALHHPPIPSVLDLA
VTVELRDQAALGRVLEGSDVRSILAGHLHYSTNATFVGIPVSVASATCYTQDLTVATGGT
RGRDGAQGCNLVHVYQDTVVHSVIPLGSGKTVGTFVSPAQAKRQIAESGMFIEPSRRDSL
FSQPPMVLTPAARPGPAR
>A0A086WKA3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. B183|TrEMBL
MKVTSCSSDGSIRLLQITDTHLFEATDGSLLSVNTADSFNAVVDAIVEESPAYDAVLATG
DISQDHSEVSYQRFEQGIVPLKKKCFWLPGNHDFKPSMNSVIPSQQIQQIDHVLLGDTWQ
MIMLDSQVVGVPHGRLSDKQLNLLEEKLSQYPERYTLILLHHHPLLVGSAWLDQHTLKDS
DDFWQVVDQHNNVKAVLCGHVHQDMNVMRNDVRVMATPSTCVQFKPNSDDFALDYQSPGW
RELLLRDNGEVETQVKRLPAGCFQPDFNSAGY
>A0A663F446|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aquila chrysaetos chrysaetos|TrEMBL
MPLVDFFCETCAKPWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQHEVE
IPAPGPKEREKKRRQPPPMGQISGVKKLPPGSGPGGSSVPRFGVKTDREDLLGKELDSLN
KWGLNIFRVSEYSNNRSLSCIMYTIFQERELVKTFKIPVETLLTYTLTLEDHYHADVAYH
NSLHAADVMQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPDSELALMYNDESVLE
NHHLAVGFKLLQEENCDIFQNLSKRQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETK
KVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKPLALYRQWTERIMEEFFRQGDRERER
GMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILETLEENRDWYHIPD
PRSPPNLPLPPSPPPPPQHRFQFDLTLEEDEEGQEPGVYPPPSSCNAPRLVHQPYVTPPE
QPPGGRRPPEEEEEEEEERNGLGGGIRCRGVVNQPPPPCRLFGEGGEVQDTPPPPPGAEL
RFILF
>A0A7U4GCY0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia enterocolitica LC20|TrEMBL
MESLFKLPMASGAKVRILQITDTHLFAGEHETLLGVNTSRSYRAVLDAILAEQHPFDLIV
ATGDLAQDHSVAAYQNFTKGISRLPAPCVWLPGNHDFQPAMVDVLANAGIAPSKHVLIGD
NWQILLLDSQVFGVPYGELSDYQLEWMERCLVAHPERYTLVLLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGRLETEVRRLASDEFCPDMDSDGY
>A0A5U9SEK1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Reading|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAVAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A429H0P0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter baumannii|TrEMBL
MTFQVSSLSQQDFVMIQITDTHLLEYPHLEFVGMQPEQSFHAVIDLMRQQHPHIDLIIHT
GDLAQSPTPLTYKRYVQHMQSLGIPFFHTPGNHDDVTHFPFHEQDPTQPTVVELGQWSVI
LLNSAQPERIDGKISDIQLQHLTRLLTQLHDRHVIIACHHHPFAMQSAWIDQHKLKNSSD
LLDTIKPFSNVKAIICGHVHQDSVNTWQGVEFLSTPSTCIQFRPKSEKFALDEEHPGYRL
IRLKANGELETQVYRLPTSQRMSSSEVLGYD
>A0A6B5QMU7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pneumoniae|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELELDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A0N1QVU7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella schwarzengrund (strain CVM19633)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>H2M1L9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oryzias latipes|TrEMBL
MPRVCKFKRMLNRELSHLSEMSRSGNQVSEYISSTFMDKQNEVEIPSPTLKEKSMSHISG
VRKLSHSSSLSSASMPRFGVNTDHEDELAKELEDLDKWSFNVFKVAEYSNNRPLSCIMYA
IFQAAFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFK
LLHQENCDIFQNLTKRQRQSLRKLVIEMVLATDMSKHMTLLADLKTMVETKKVTSSGVLL
LDHYTERIQLLKNMVHCADLSNPTKPLPLYRQWTERIMEEFFRQGDKERERGMEISAMCD
KHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQELLDTLEENREWYLTTMPQSPSPPPD
RHLQHDRFQFEITLEDLEHNNYNHVQHLKETKRASDALIS
>A0A7X1BPT7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter cronae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEFDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSSLQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVCRLQGNRFHPDTASEGY
>A0A1Y2SLU6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus beddingii|TrEMBL
MESLLELPVAEGATARILQITDTHLFANKGDSLLGVNTYRSYHAVLDMIIEQDLDIDLIV
ATGDLVQDQTINAYQHFAEGIARLPAPCVWLPGNHDYQPAMVDTLAAAGISPSKQIFIGQ
HWQLIMLDSQVQGVPHGELTDYQLEWMNKCLDEHRDRHTIVMLHHHPVPSGCTWLDQHSL
RNAPELSRFLRGKTQVKAILCGHIHQEVDEMWNGIRVMATPSTCVQFKPHCTNFMLDTVA
PGWRYLELSVAGSKEAGLQTQVHRLKNNPFCPDLDSDGY
>A0A5B0FTE1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. ANT_J12|TrEMBL
MPSVSTLTTADPALLVQISDSHLFAEADGTLLGMNTRESLQKVIELVRVQQPRIDLIIAS
GDLSQDGTLESYQLFRDLTRQLDAPARWIPGNHDEPRIMAEAAVQSALLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
GLFAVLDRFPQVRAVLWGHVHQEIDQMREGVRLMASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLMPDGLIETGVERVTGFEFTVDYGSNGY
>A0A432ADA5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. C 49-2|TrEMBL
MPSVSTVSPDAPALLVQLSDSHLFAEADGTLLGMNTRESLQGVIELVRAQQPHIDLVLAT
GDLSQDGTLESYQQFRDMTRQIDAPARWIPGNHDEPQIMARAAEHSDLLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDQQLQRLAQALSEAPNRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERLVGFVFTVDYGSNGY
>A0A7R9JPQ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Timema genevievae|TrEMBL
MRITSGKYREFDSKKIVATLLKYCLRPQLSGDEWQTLLIAAPSVPEILSPLLRLTSPMLR
ALSRRRMSWARMYRTHLLDLPFSCRCRSSLIVNILLVPIVAETLDNPPTAAAPDPVRGPV
CACARPRDQGIGRVGFKGSEPAFAWKESGKPFRKNHPSSPDRDSNLDLPSSAVELNTTGA
LANYANEAVGFADAINIVVGLAGAINIAVGFSAAINIPVGFTAAINIVVGLAGAINIAVL
LVFPKDDFNSDALWYASEKLGYECHLARTENAAVEVFESRHHDIVIVDNRYPRVMNGDKV
CQNLRAAKGSKFTVIVAVVKRSLAEKDDPIVHNFLAVGYNRIFLETSSLGICMNELLTLE
KSDVIPRASLAATQAFHLTLNKCSELVHITNHEHTIEFVNQAVEYHMGFPRSTMLGKNLM
EMCRLEVNELMVQELQKGREWEGVITWYTRTGERLILSGRVLPFSLPGRPPSLYVYVHES
PTMSEKRSSQSIVPFSQQIFQPSAAQRGSITSAGTRRQSLAKLYNLQIQAPITRIIELIN
SAQEEAAEPVVQILDKVIDIVRTTELYTPHMKERPIKLTDPVTSDLISALLMQGGTGTTA
SLTRRSSSESSAFKNPLSIPGTTKGTMYLAGSSKMKDLLDTALNWDFDIFSVEQISEKRP
LVHVGMSLFLHFESHLALGCDESTLKNWLTIIELNYHSTNSYHNSSHGADVMQAAAGFLK
TDRLMQTLDSLDRAICLIAAAAHDVDHPGKSSAFLCNSDSDLALLYNDLSVLESHHAALT
FKLTMSDERVNIFKGLERDTYKIVRQNIIDMILATEMTRHFEHLAKFVNVFCKGGIQDEE
SVEAKADQMDMLAYSPENMSLIKRMLIKCADTDEEKANNLPVVMPLFDRSTCSIPKSQIG
FMEFIIRDMFEAWEAFIEMPELLQYMERNYIFWKDLEERGISSIQDIIKNQRIGETGH
>A0A8E6VUX3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Shamba|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A3T0CQR3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter sp. NP-4(2019)|TrEMBL
MTRKDKPRALRVLQITDPHLLADPAGGLLGVNTRDSLDAVIDKVVRDHGQPDLVLATGDI
AQDGSEEAYRVFGEKLSAFPCASAWIAGNHDDSDVLAQVAGEHQANRRHIVQGGWQFILL
DSSVHGQVYGELAESELEFLASTLAQNPDLPALVALHHHPVDIGSDWMEGIGLRNRDAFW
QIVECFPQVKIVLWGHIHQEHDLERRGVRLLATPSTCIQFTSGSPTFAVEALPPGYRWFE
LETSGQFQTEVQRATDFEFELDVNSTGY
>A0A200LLA5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella sonnei|TrEMBL
MESLLTLPLAGEARGRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7M1KCP3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas poae|TrEMBL
MPSVSTVNPDASALLVQLSDSHLFAEADGALLGMNTRESLQRVIALVREQQPQIDLMLAT
GDLSQDGTLESYQQFRELTRQIDAPARWIPGNHDEPQIMAHAAEHSDLLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPSRHHLVCFHHHPVPIGCAWMEPIGLRNPD
ALFAVLDRFPQVKAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERVEGFAFTIDYGSNGY
>A0A379ATR2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Avibacterium avium|TrEMBL
MIDTYTHSTNEDVVRLIQITDPHLFNDENGELLGINTQASFNQVLEEIKQSEFNYDLVLA
TGDLVQDSSNEGYLRFCQSVQKLGKTVFWIPGNHDFQPKMFEILNHNNGQLSPAKHLLLG
EHWQIIMLDSQVSGVPHGQLEPAQLDFLVEKLKAYPQRYALIVLHHHILSTNSAWLDQHN
LRNALELANVLLPFKNVKGILYGHIHQAVDSQWQGYQVMATPSTSIQFKPDSNTFALDTL
QPGWRELELYSDGQIKTRVKRITQKQFLPNMLSEGY
>U4DVZ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio nigripulchritudo FTn2|TrEMBL
MKLSLDSSRDIKLLQITDTHLFEPEDGCLLSVNTFESFKAVVNAIRSNEIEFDAILATGD
ISQDHTAVSYQRFEDGIALLKKPCFWLPGNHDFKPEMHSILPSTQIQTTQHVVLNDKWQI
ILLDSQVEGVPHGRLSEEQLALLDAKLSEYPNHKTVVLLHHHPVLVGSHWLDQHSLKDAD
AFWSILSKYDKVEAVLCGHVHQDFDVIYQGVRVVATPSTCVQFKPNSDDFALDNLSPGWR
MLTLTHYGELELEVGRLPDGEFLPDFSAGGY
>A0A2T0BQK2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clostridium luticellarii|TrEMBL
MALFAISDLHLDMTGNKPMDIFGDNWIGHDEKIKSNWIDKVKDEDTVLIAGDMSWSMNMG
NGFLDLEWIHDLPGRKVMVKGNHDYWWGSITKLNNLYEDMDFIQNNFFVYKDYALCGTRG
WSCPGSENFSQHDEKIYNRELMRMRNSLSRAEEAGYSKFIVLIHYPPIGERFMNSGFRDI
FEEYSVEKVIYGHIHGNASMKAETGELNGVEYILTSADYIDFDPKIIIGK
>A0A8I0CV07|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas tritici|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHSENRHCDLIA
ATGDLAQDQSAAAYQHFATGIASFSVPCVWLPGNHDFQPAMYSTLHDAGISPAKRVFVGE
HWQILLLDTQVFGVPHGELSDFQLEWLEKKLAADPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLSKYPRVNNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLQSATFRPDTASEGY
>A0A2J8WPP2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pongo abelii|TrEMBL
METLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTF
LDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLA
KELEDLNKWGLNIFNVA
>A0A444UTM2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acipenser ruthenus|TrEMBL
MPCCHCERASLSGIDSIFLASLWYLHTVHFEVENGPSPGRSPLDSQASPGLVLHPSFPQS
QRRESFLYRSDSDYDMSPKTMSRNSSITSEAHTEDLIVTPFAQVLASLRSVRNNFSILAN
VTTPTNKRSPVVSQPTVSKASLSEETYQQLAKETLEELDWCLDQLETVQTYRSVSEMASN
KPVVLETAAAPPPLTQVLETAGLPASTSGAAAPVVLSSVLLFPTGGNPGSRLHLSISS
>A0A4R0ERX9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. ANC 4178|TrEMBL
MTLKQRHDQQQSWTIIQISDTHLMNQDDLEFVHMNPEQSFHRVMAQIQHEYPHAHALIHT
GDLAQVPVPETYQRYLDFMQTTGFQYYQVPGNHDNADFFPFYQQQNKVHAIPMGNWCLVL
LNSAVKGKIDGWIDTEQLKQLDHILSLHAEQYILIACHHHPFEMQSRWIDQHILKNTEHL
TDVLAKHSNVKLVLCGHVHQASENQWHGIHFLSTPSTCVQFKPRSDDFALDDEAPGYRIV
QLKANGEFTTQVHRTQPIQKKINIEITGY
>A4MY26|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae 22.1-21|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNVAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLIVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAEFLPNMQEDGY
>A0A4V2X5F8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus khanii subsp. guanajuatensis|TrEMBL
MESQFKLPVVEGTTAKILQITDTHLFAGKEETLLGINTYRSYHAVLDAILKQNADIDLIV
ATGDLAQDQSLDAYRHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGE
HWQLLMLDSQVAGVPHGELSEYQLEWMKKCLDSYPERYTVILLHHHPLPSGCTWLDQHSL
RNSHILAEYLQGYSRVKAMLCGHIHQEMDLGWNGIHMMATPSTSVQFKPHCTNFTLDTVA
PGWRYLELSISDRGEFGLTTQVHRLESNEFCPDLDSDGY
>A0A2S0Q833|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nodularia spumigena UHCC 0039|TrEMBL
MHWLFTGRLRVDKITVKIADLPQSLQGTKLVQLTDFHYDGVRISEELLAQAIAASNEAEP
DIILLTGDYVTDDPTPIHELALRLKHLQSRCGIYAVLGNHDIHYKHSKTEITSALTSIGV
HVLWNEIAYPLGQELPIIGLAEYWSREFNPAPVMDILNSDIPRIVLSHNPDTAKILQKWR
VDLQLSGHTHGGHIVLPGLGPAIFHYQKLLKQLPKKLRRWEPLLLGDCGKVVKYWEWAKG
FHQVSNNQLYVNRGLGTYRPGRLFCPPEVTVITLVSL
>A0A4P9URW4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylotuvimicrobium buryatense|TrEMBL
MSTQGALSLLQLTDLHILPSPGEKMLGVDTEFYFEAVLQHARKTNTHYDLVLVTGDLTQD
PCPEAYQRIFGRLQALSVDTLCLPGNHDDYALMQQWLNQDNISCKKHIEFKHWQVLCLNS
QIPGKAEGSLSENELRFIEDALEKKPNLFTLIAVHHHCVPTRSSWMDTMIIKNSDEFLEI
AGRYPQIRGLTTGHIHQEMDIHLGSLRILGTPSTCFQFKPLCSRFTLDELMPGYRTIELH
SDGRITTQVHRLPGILQEIDRNCTEY
>A0A6B2AYB6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas syringae|TrEMBL
MPSAALSSSVLLVQISDSHLFAEADEALLGMSTRDSLEKVVDRVLAEQPHIDLVVASGDI
SQDGSVESYEAFRQISGRIDAPARWFAGNHDELPQMEQVAQHHGLLDPVVDIGQWRVTLL
DSAVPGSVPGFLAAAQFQLLEQSLSEAPERHHLVCLHHHPVAIGCEWMAPIGLRNADALF
AVLDRFPQVRAILWGHVHQEFDQMRNGVRLLASPSTCIQFAPGSVDFKVDTAAPGYRWLR
LHDDGRLETAVSRVVGLEFEVDYGGTGY
>A0A2H6AGF3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR36|TrEMBL
MRPKRQVPDSQRDRPRSASSRNSTRRRGLAYWLGRAWAHWTYARHVEPHWLEVTRWQLPL
ANWPEALDGLRIAHLTDFHVGRRVPLSLLVEAVDLANAQKPHLIALTGDFVHAGRGYVEQ
VAEVLSRLRAPLGVVAVLGNHDFAKRTRLGWAHSGLPLRIEAALRQRGVRVLRNEAWQVE
RNGAAFYVVGVDDLWSGRCDVQAAFRGIPAQAPCLLLAHHPQTIERLAGHRAILTLSGHT
HGGQVNWPGLGPLFLGGKMRRWATGLFHQRNGWLYVNRGVGYGLRLRYRARPEVAVFTLL
SRNENRLAHGRHL
>A0A6B2FK56|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacteriaceae bacterium 4M9|TrEMBL
MESLLNLTVNSGATVRVLQITDTHLFAEKNSTLLGINTWESYQAVMAAIRAQQRDCDLIV
ATGDLAQDQSAVAYQHFVEGIADFPAPCVWLPGNHDFQPAMYSTLLDSGISPSKLIYAGD
AWQIVLLDSQVFGVPHGELSEYQLEWLEKALSLAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDEVLKRWPQVKTLLCGHIHQEMDADWNGRRLLATPSTCVQFKPHCTNFTLDTIA
PGWRWLELGADGTLTTEVCRLADAAFRPDTASEGY
>A0A3B4A1H0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Periophthalmus magnuspinnatus|TrEMBL
MLPCFLCLILLSHLSEMSRSGNQVSEYISNTFLGKSITEMEYPHVQTAEQPQQQSGMMNQ
ISGVRKLSHLPNISGSTVHRFGVKTDQEELLSKDLEDINKWGLNIFKVAEHSHNRPLTCI
MYTIFQAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAV
GFKLLQEDNCDIFQNLTKKQRQTLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSG
VLMLDNYTDRMQVLRNMVHCADLSNPTKPLDLYRQWTDRIMDEFFHQGDRERERGMEISP
MCDKHTASVERTQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRNWYQSMIPQRSSQ
GELEEPPMPNKFKFELTVMDQSGQTGQRESGTVHADVDGLPDQPCDESRDAET
>A0A3B4BGQ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Periophthalmus magnuspinnatus|TrEMBL
GGQDRERGEAGEGEGGKKEEEMEKRGGERDRNGLSVGRSPLDPQTSPGSGLVLQANYPHS
QRRESFLYRSDSDYDLSPKAMSRNSSTASELHGEDMIVTPFAQVLASLRTVRSNFAALTH
LQDRAGNK
>A0A2R8CIC4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kushneria phyllosphaerae|TrEMBL
MFHLVAALPWGIVVLRYLLPLTAPLWIKLALALVLLIVAEQHLISRWITGSIFSPETPRP
LSMTLNALFGALILLAVFQLLMDLVMLITMLVKQQRMAAPPMARYLIGLLALGLGIWGVQ
QAARVPPVKDIEVAIPGLAPAFEGYQIVQLTDLHISGLFPETWARAVVERTNALNVDAIL
ITGDLMDGTLENRRDDVAPLAGLHAVDGVFVIPGNHEYYFGYEPWMQHYVSLGMQRLSNS
HAFIERDGARLAIAGVTDPAGPSRGLPGPDVAAAVEGIPAEVPIILLDHQPKNARGAARE
GVALQLSGHTHGGMIIGMDRIVARANNGFVSGRYNVDGMTLYVSNGTALWMGFALRLGKP
SELTRITLRRE
>A0A5J4DQ81|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|archaeon MnTg01|TrEMBL
MVVKTVIVPSQPALLLQGSSRSVIISDLHIGFESKLVSNDIFLGKNTTTDETINEIESII
DSTKADSLILLGDIKSSIKSISKSEWNDVPKFLKKMKDRVDTVLIPGNHDANIQKLVPDG
ISLGSSVGMVLENILLTHGHTIPSENFSHVDKIIMGHVHPVFFQEGSVLNGQRVWVSIKT
EKHQIFPSVSGELEIIIVPSFNRYFYATQKKFYKKSISPILEKIKKYSSVKIVTLDGTII
GDESIINQVL
>A0A7X5QL76|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus stackebrandtii|TrEMBL
MESQFKLPVVEGTTAKILQITDTHLFAGKEETLLGINTYRSYHAVLDAILKQNADIDLIV
ATGDLAQDQSLEAYRHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGE
HWQLLMLDSQVAGVPHGELSEYQLEWMKKCLDIYPERYTVILLHHHPLPSGCIWLDQHSL
RNSHILAEYLQGYFRVKAMLCGHIHQEVDMDWNGIRMMATPSTSVQFKPHCTNFTLDTVA
PGWRYLELSISDRGEFGLTTQVHRLESNEFCPDLDSDGY
>A0A1Z3N0G0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae complex sp. ECNIH7|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLTGAKFRPDTASEGY
>A0A4V2SJX9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nicoletella semolina|TrEMBL
MESYSFPDLNQVIKIIQITDTHLLANGDQELLGVNTAKSFQAVIDGIHRGEFAYDFILAT
GDLAQDQCSQAYTRFAEMVKPLEKPVFWLEGNHDIQPAMYQGLTPFPQIQSEKHILMGEK
WQVLLLDSHIPTLSKGELSQDQLNWLARKLEEYSERFTLIALHHNILPTNSAWLDQHSLA
NSEALTTILAQFSKVKAILYGHIHQEVDRFWLGYRVLATPSTCIQFKPNCDRFTLDPMPQ
GWREISLFPDGNIETTVRRLNENNFLPNFHATGY
>A0A7Z1Y144|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea vagans|TrEMBL
MDSLLTLPAANGSEIRILQITDTHLFAGKHESLLGVNTWSSYDAVLDAIISQQRDYDLII
ATGDLAQDHSVEAYQHFAEGISRLPRPCVWLPGNHDFQPAMVDTLAAAHINAHKQVLVGE
QWQIVLLDSQVYGVPHGMLSDYQLEWLDNALSRFPQRYTLVLLHHHPLASGCTWLDQHSL
RNSHQLDAVLQRYPLARTLVCGHIHQELDLEWHGRRVLATPSTCVQFKPHCTSFTIDTVA
PGWRWFTLHPDGGLETEVNRLDTDAFRPDLDSEGY
>A0A6P4LKA8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila bipectinata|TrEMBL
MRNCLPKFSRVFRRKSSAKSGRENPSNEPDSDGEPYTAVIRPTALSDPPSDNHNESSPSR
LISPANTDLDLDLNLDSGVPAINGGIQGSWPEMKVETISAAAAAEATAAASVPASVAISQ
SFGGRNSGKTPEEMELEYEENVKAEGRDIVTPLRRNTRPLSVAFSGSGRSALQPEIAEVI
RSLDVPALLLNNLSLDTKNRECERETDCYDHEDSCEVVLRRKANCLERKTRSLYERRLPK
VPKLHLQVAGKKTSEEEEFRIFQRNLMDLKYPTVLPPNPQLKALLVFYKADSICEAVSAA
CQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSSKNLDAEHIARTIRHTHGHH
LTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMST
QQALYTALHRLKEVVLITDDVLRIQYANRATERLLNMRLDEIISKPLADIFVSDLSTISE
QGKSIKEFDGILTVRRKNQEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQ
PKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQENCSA
DEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRT
GSSTRTATIVPAKMKANPIIMELLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVF
ATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADVMQATGAFITQLTNRDMMVMDRMEE
ATALIAAAAHDVDHPGRSSAFLCNSNDSLAVLYNDLTVLENHHAAITFKLTLGDDKINIF
KNLDKEQYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGDESREPHAQTEEETSILMRR
MLIKVADVSNPARPMQYCIEWARRIAEEYFMQTDEEKQRHMPIVMPMFDRATCSIPKSQI
GFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGINTLADIMAKQPPVGKLAN
SK
>A0A6P4LDW6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila bipectinata|TrEMBL
MNRSARPSCTGTSGTSSSGGGNSRPGHRKSSLAFALTPEDEPMDVYQRNLMDLKYPTVLP
PNPQLKALLVFYKADSICEAVSAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIII
DARSSKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTN
LAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLN
MRLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMHVRVVPVACIGS
APTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLT
SLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDL
IGALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKANPIIMELLDESLSWDFDIFK
LEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADV
MQATGAFITQLTNRDMMVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDSLAVLYNDL
TVLENHHAAITFKLTLGDDKINIFKNLDKEQYKSARSTIIDMILATEMTRHFEHLAKFVS
VFGGDESREPHAQTEEETSILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYFMQTDEE
KQRHMPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKK
YDEQGINTLADIMAKQPPVGKLANSK
>A0A7U9NYX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli HVH 36|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A1G4XZ20|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kosakonia sacchari|TrEMBL
MESLLNLSLAGEPRVRVLQITDSHLFAEKHETLLGVNTWESYQAVLEAIRSQQRECDLIV
ATGDLAQDHTAAAYQLFADGIASFDAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGD
HWQILLLDSQVFGVPHGELSEFQLDWLEKKLTDSPQRHTLLLLHHHPLPSGCSWLDQHSL
RNAGELDNVLQRFPQVRYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLYPDGTLHTEVCRLESTQFRPDTASEGY
>A0A4S1DJF2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter pittii|TrEMBL
MTFQVSTLSQKDHVIIQITDTHLLEYPHLEFVGMNPEESFHAIIQQIINKHPEIDAIIHT
GDLAQAPTPITYKRYIQYMQTLGLPFFQTLGNHDNVDHFPLHKENHQEPVVICLGNWRVI
LLNSAVKGHIDGHLSAEQLENLTNLLEEYADNPILLACHHHPFAMKSKWIDHHKLQNSNA
LLTTLAPFKNVKALVCGHVHQDSINTWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLKNDGSFETEVFRLENFQGHINTDISGY
>A0A834R8X0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sarcoptes scabiei|TrEMBL
MGCTPSTINHGESTANTQFIDQTTTTSHYQRQRRCDLVPSTKAKNNKFFNHIEKERILEK
NDSRLNRSSSPSPSSSPSSSSLNDNMINNNNSNNNHSDRHRARSSNSSSQTNNYLCGLLS
FSMDLCYHCHPHTDSHRQHSEKERKNFRFGRRKKILKIATGDNGGGDGRGDDDCDGAERS
SRLSKPISASLTGLHSLIDRESNCSQDEFQRLSNATNVMGNASSDNLSPPPPPPSSKIKI
LGMKKLQSSKTNSIQPNSDRINHYDLNKNVKNSKLIIDDNNNENNHNDNNSNNNNNNCKS
SNNNDCNRKIDTSIDDQHSNVSCHLCEEERKMMMFSNDSISTPRNSDNNNLAQKNFDSIV
RYDISEDRNTVSVWNSSIDQSDITINNDQTRTTMPVWSVTQATPPTSNLNRWPLSQSSHS
SLSSSLTSSRKFCCRHSHQSKVNESSEHHSYCCLHRKQSDYDCSRKNDPMSSSSITIQQP
TYFTSLIASSSSANTKDLHHTNQLGESSMAPITTATTMFQKCSKINQDHHQNCFNFKHQQ
QQQQQSSQSSMTSKMNTNNKNNKSVHGLIESNKNSNSSQLHQQQRINNDGQSNQSIRFGR
MNVSLRKPRLLLVTYADRDDDREFRLLSKAAKRIGFEVIINSVHNSNENVLNAYIENQFE
LIIIDVRDFDFNSLRNSPNQTDCPANNGNQTGCNNNNHRHHLIDLHSAKDSDDGHHHSHS
HHSHPYSLNDSNDSKQSRSINLCKSIRSLKLNEFTTIVALIDGDQIYGIDFNDDDNDDND
DGGGGAETSQSFWSRSQHFLRQIGFNKSISSSKSSPNHYLNELNHLKEFDLVLQQRLRAS
SILFQALDNCKDGVIITGPQHDIRYANHSIEKMFGFRLDDLIGQRTQDFFQNDLLKFDVD
EKIHNYNDGKEWEGSIYHRRKSGESVPIWNRILPINYHQGVPEHIVYIKEYPFFCIEKLY
SPDKESLSSHGSFKGHRKYSVDCRNEARRPSLAKFNSISLIEAPITKVINILMMIKENGP
NSLAPTLEKAIDILKNSEIFTNLSPQLQNLKPDDQLTSELVCSLISTNKTQANRRMSHEV
ASNKSSISYTTSTNSVINTNSNSNNSNNANNINDNNMIASAIPAEIQSLLDDDLKWNFDV
IELERITSKSPLLWLGQSILEKFNVRQTLNCNDSTIRNWLTVIESNYRNNPYHNSTHAAD
VMQATACFLQSERLRNLLDPLDQAICLIAAIIHDIDHPGRNSAFLSNSNHELALLYNDIS
ILESHHAAYGFRLTVGDNSDHINIFKNLDRETYIEVRQSIIDMVLATEMTKHFEHLSKFV
NVFQTFTLNDTNETTLIDTLEQTKSSSANLNNQASNKIYRKNSDEIACSSSTTPADVCSM
ISLSEWSSPENIVLIKRMLIKCADVSNPGRNIKLCRIWAERIASEYCDQTEEEKIKGLPL
VMPTFDSKNCSIPKSQIGFIDYFANDMFEAWHSFGDFPEMVENMNTNYQYWRDQLASTEP
KKLSQESTVSTTNPCNDESAPIKEVEEE
>Q9KPD7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFAAEDGSLLSVNTADSFAAVVAAIGEEQVEFDAILATG
DISQDHTPESYQRFVRGIQPLKKACYWLPGNHDYKPSMHSVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEYPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRIHLGARVMATPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A7Y5ADB1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. CM27|TrEMBL
MPQQDQSRPVHVVQLTDAHLFADPAGSMLGLNTRDSLRHVVAQVRREQPLVDLLLCTGDL
SQDASVASYEAFRELTAPFGVPTRWLPGNHDEAQVMAQVAPELVQAVTDIGGWRIIMLNT
AVHGAPHGFLQEDQLATLESALKGAGERHCLVCFHHQPVDIGCAWIAPIGLRNAQAMFAV
VERYPQVRALLWGHVHQPWDEVRNGRRLLATPSTCIQFAARSEEFQVSEEQPGYRWLRLH
ADGRLDTGVERALDFAVKLDFDSPGY
>A0A7H2T9Z9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter seifertii|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIKQILKQHPEADAIIHT
GDLAQAPTPLTYKRYINFMQTLGLPFFHTLGNHDNVDHFPLHNENHQEPVVVGLGNWRII
MLNSAVKGKIDGHLSSEQLKNLANLLERFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFKNVKALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSKDFALDQNAPGYRY
IRLNNDGTFETKVFRLENFKTLINTDISGY
>A0A8F8F4U1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia sp. R33|TrEMBL
MDSQLEVTAKHSNIVRILQVTDTHLFANTENTLLGVNTYKSYQAVLDAIAAQNLPIDLIV
ATGDLVQDQSPKAYQHFAKGIERIPAPCVWLPGNHDYPPAMVESLRVAGISSAKQILIGE
EWQILMLDSQLQDVPHGELSEQQLEWMKASLDAEPQRTTLVMLHHHPLPSGCTWLDQHSL
RNSHILADYLKDYPNVKAMLCGHIHQEMDENWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELSVNEKGQRHVTTTVHRLETREFSPDLDSDGY
>Q57JS9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella choleraesuis (strain SC-B67)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A0A3A4T2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gallibacterium anatis 4895|TrEMBL
MSDLFRDESAGVIKLLQVTDPHLFADEDGELLGINTFDSFRQVLSEIKKSGFESNYILAT
GDFVQDNSEAGYHRFVKEIVQLGKKIFWIPGNHDFQPKMEAVFDLYKAVIQPEKHLLLGE
SWQVILLDSQLYGVPHGMLSEEELKWLEQRLSLYPDRNTLIVLHHHLLPTNSAWLDQHNL
RNPYDFSEILAKHQKIKAIVYGHIHQEVNAVWQGIPVFATPSTCIQFKPDCAYFTLDNLQ
PGWREISLYPDGRLETKVHRIKDKVFLPKDNMNGY
>A0A6G0ZKQ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aphis craccivora|TrEMBL
SLRSIRKNAHVVLVALVRKSLVLKNEKDVTSILTSGFNKIIVETCNKNVWIKELQQLEKE
EVAMRSMLAQQDAVLAALDKTKDLVIITDLKHNIQNKTAYYMNKSGSVILGYGVEDVINK
PLAVFHQLCDIDQITKKLEKNIEWDGKVSWKCKSGEHVYLHCRASPFRSFGKETTNYIYI
QESIVDVHGFPRGSVPSIRKGSYDLKSINSDGAQSARRQSLAKLHNLPLEAPITKVISLI
CTAQENSNDQVVQILDKVVDILRVTELYSSHLKTENIKYDDPVTSDLIGALITQGPVHVT
STRRSSNDSATVKSQPYGLGVAKMNFMTSVTPQIKELLDMSLYWDFNVFKLEELTMKRPL
VHLGMNLLTHFEVHKTLGCDERTLHAWLTVIEGHYHAKNTYHNSTHAADVLQATAMFLEK
DRIKRLLDQLDEACCLIAAITHDIDHPGKSSAFLCNSKNDLAILYNDISVLESHHAALTF
KLTTKDERLNIFKGLEKDTYKVVRQNIIDMILATEMTKHFEHLAKFVSVCNKPSTLDEAP
VDGLTPSEVSPETIMPTSAEEVNLVKRMLIKCADVSNPTRPLKMCVEWAKRIAEEYFNQT
DEEKLNHLPVVMPMFDRASCSIPKSQIGFMDYIINDMFETWDSFIDMPEMLYYMRSNYQY
WKDLEEKGTISFNDICKMVTTTLPKIPESSGNH
>A0A8E9YGD9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. diarizonae serovar 60:r:e,n,x,z15|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLVLQANGVLETEVHRLQDTRFRPDTASEGY
>A0A2S6UH21|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alphaproteobacteria bacterium MarineAlpha4_Bin1|TrEMBL
MIIAQITDMHVMAAGQMAFGRIDVNANLAAALARLAAHDPRPDIVLVTGDMTFDGEVDEY
TALAGIMAGCDIPFHVMPGNHDNRARIRAAFPGHDYLPRGGFLHYTIDAHPLRIIALDTL
NPESVDGQLCARRLDWLAARLAEAPDRPTLIAMHHPPIDIGIGWLASDRFEGRDAARDII
ARHGQVVGVICGHVHRCVQAQWANTVVHTGAPTAYQFPLDLKPHAERGWVAEPPAYSLHY
WRAESGLVSHTGYADGFGAAQEFIE
>A0A2H5YMC3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR25|TrEMBL
MTARETSLRPAALRRRRPLRLLHTSDLHLGAHDGRWRANGHRDPGLEMLERVVATALAER
ADVVVFAGDFFDSNRVRTEVVEAAAELLRRLPMPTVLLPGNHDCYSPDSVYRRFDLPAYH
PALHLITSGEGEWLRFPGLDLAVWGRAHLSYSDSRPLRDVPPRGNERWQVAVAHGHLVRG
DYDLGRSYQIYAHEIEASERDYVALGHWELMTDVSVGPVVAAYSGSPETTHHVLIVELGE
GVRYRQCPL
>A0A0P7VAZ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Scleropages formosus|TrEMBL
MNQEVSECYKTAKVPVQGASDARLSNGSSATQCQAVGGHLFGKKLEHGQSSRERRREGGR
FDVENGPSSGRSPLDSQASPGLVLHPSFPQSQRRESFLYRSDSDYDMSPKTMSRNSSVTS
EGHTEDLIVTPFAQVLASLRTVRSNFTILANVTTPTN
>A0A6J5A0I6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter insuavis|TrEMBL
MARVHTLARRTDAPAMLVQLTDCHLFGEPDTVMLGVNTDASLRAVLRQIEADGKHPDLLL
ATGDLSQDGEPAAYQRLAAILGAAPALEGARIRCLPGNHDLPVAMRHELPEWSVPVTDVG
AWRVVSLDTTVPGSNAGHLPDSQLDLLEAALAEAPGRHTLLAMHHNPMQIDSHWHDSMMI
DNPQALFKLLTRWPQVRVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNLA
PGYRWIKLYQDGSMATGVRRVQDALWQATQPGPDSAQAA
>A0A2S1FC99|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter schindleri|TrEMBL
MTQTSTPASEKVWTLIQISDTHLMDQPELEFARMNPEQSFLEVVHDIQQRFPHIDAVVHT
GDLAQVAAESTYQRYLQFMQAWNVPHYQIPGNHDDYLAIFPFYKNSDEAHAISFGCWTLI
LLNSAVKGRVDGWVEQKQLDQLEQLLLEHSKQYVIVACHHHPFAMQSHWIDQHRLKNSEA
LKDVIARHTNVKMVLFGHVHQDSENKWQGVRYLSTPSTSVQFKPLSENFALDQAQPGYRV
LQLKDNGEYQTYIQRVVLKQAKINTEISGY
>A0A371YPE6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sichuanensis|TrEMBL
MSMHHVISKPKDHILIQISDTHLMTDPNDGFIGINPEQNFHQVIAQIQQQHSQIDTIIHT
GDVAQEANPTTYQRYQAYMQRLNIPFFQIPGNHDHLEYFPFAASALVPAVIDLDPWRLIL
LNSAVPNQVDGWIQTEQLQLLEELLYSIQDKFVLLACHHHPFAMKSKWIDQHKLKNTDQL
TDVLAKFKNIKIVLFGHVHQESNTLWQETEFLSTPATCAQFKPLSEDFALDEAAPGYRYL
HLKSDGQFETSIYRLEGYIPTINKEISGY
>A0A7Y0RFH3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter orientalis|TrEMBL
MTENDSPHALRVLQLTDPHLMADPGAELLGINTRESLDAVIAQVLHDRGQPDLILVTGDI
AQDATEEAYRLFGNKLEAFHCPSAWIAGNHDDSPLLALIAAERKADLRHVIQGGWQFVLL
DTSVPGKVFGQLADSELAFLEKTLRENPETPALVALHHHPVEIDTDWMSPIGLRNRDAFW
QVVDRFPQVRIVLWGHIHQDLEQSRKGVCLLATPSTCIQFTAGSTEFSVEDKAPGYRWFE
LLPSGEFFTEVSRAEDFVFDLDSNSSGY
>A0A2H5Z4L9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR28|TrEMBL
MVSKVVPLRRLVPWVSALGLLVLARASLEPRRLQFRIVRISLPRVDAPLTGLRLAFLTDF
HIGGPGPSAALTVAALEQLRAWEPDIVLLGGDYFDQGRIVPTTVFDSLPLFPRVYAVLGN
HDHRRGPENASAIARFLASRGAIVLQNERLLVTVERNHRAMTVELVGLDDPYTGLDDPSL
LANPPGAFPRILLAHAPLLLDRIPIGCADLALFGHTHWGQIRLAPSRQIGLLDAAWYFDR
IRRKPHSRLQRGWFWERGMLAYVSAGIGLTQLPFRLFAPPEVLLLEFDAEAMDPRWPCDD
PRRFVRVANSW
>A0A6G6QAT3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia sp. 1709051003|TrEMBL
MDSQLEVTAKNSKVVRILQVTDTHLFANTENTLLGVNTYRSYQAVLDAISEENLPIDLIV
ATGDLVQDQSPQAYQHFADGIARIPAPCVWLPGNHDYPPAMVKTLRIAGISSAKQVLIGD
EWQILMLDSQLQDVPHGELSEQQLEWMKASLDAEPERTTLIMLHHHPLASGCTWLDQHSL
RNSHILADYLKSYSNVKAMLCGHIHQEMDENWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELSINEQGQRHITTRVHRLDTREFSPDLDSDGY
>A0A5I6RAV0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Glostrup|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A7U3PQ18|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio europaeus|TrEMBL
MKVTSSSSNSDSIKLLQITDTHLFEPVDGSLLSVNTLDSFNAVVAAIVEENQSFDAVIST
GDISQDHTAESYQRFEQGIAPLKNTCFWLPGNHDFKPSMNSVLPSTQIKQVEHVLLGEHW
QMVLLDSQVVGVPHGRLSDQQLALLEDKLSQYPERHTLVLLHHHPILVGSRWLDQHTLKD
AHHFWEVVEKHSNVKAVLCGHVHQDMNVLHKGVRVMATPSTCVQFKPNCDDFALDTLSPG
WRELELHSDGQLTTQVKRLPYGCFQPDFNSAGY
>A0A545UBZ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aliikangiella coralliicola|TrEMBL
MSVKVEKIPHEIQPGRLDVVRLVQVTDSHIFADPEGCLLGLNTRDSFEAVCERVQREEWR
PDALLATGDLSQDASPESYQYLADYFKEMGIPTYWLSGNHDNPETMELYLSNNKVFSAKQ
LLIGHWQIILLDSSVRGKVHGNLAVEQLKFLERALKRYPEKHALVSLHHQPLPVGSQWLD
QIGLKNSDKFCEVLERYPQVKGVLWGHVHQEFNKHINGCQWIASPSSCVQFKPGSSDFSA
GTEAPGYRYLNLFSDGRIESIVHRIDNMEFTVDYSIKGY
>A0A7W2LVQ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas juntendi|TrEMBL
MHADHPRPVHVVQLTDAHLFADPAGSMLGLKTRESLGHVVAQVRREQPLVDLLLCTGDLS
QDASVASYEAFRELTAPFGVPSRWLPGNHDEARIMAEVAPELVQAVTDIGAWRIVMLNTA
VHGATHGLLGDDQLAVLEAALKGAGGRHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDII
GGYPQVRALLWGHVHQEWDEVRDGRRLLATPSTCIQFAARSEDFNVSEEQPGYRWLRLHA
DGRLETGVERAWDFEVKLDFDSPGY
>U6D4T0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Neovison vison|TrEMBL
EELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQ
HEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDV
NKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAY
HNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSEL
ALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNL
LADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSN
>A0A8D4QVB6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNVAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLIVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELYSDGSIRTQVKRIQQAEFLPNMQEDGY
>A0A2S9RRA0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNRFVYQTEKPVIKLLQITDPHLFKDESAELLGVNTQTSFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQAVLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLVPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTQVKRIQQAEFFPNMQEEGY
>A0A8D4QWT3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNEFDVILA
TGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQAVLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLVPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELYSDGSIRTEVKRIQQAEFLPNMQEEGY
>A0A6G8JJP9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mannheimia granulomatis|TrEMBL
MNESLKLDKKGAIRLLQITDPHLLSTPQETLLEVRTVESFAAVINQINAQVEETSQPFDL
VLATGDLIQDHHIAGYHHFAKITAKLNTSIVWLEGNHDTQPDMGEILASYPHISPYRHIL
IGDYWQILMLNTQVIGRPYGELSSEQLVWLEKTLNQFPERFSLIAQHHNILPTNSAWLDQ
HSLKNADKLAEILIKFKKVKGIVHGHIHQQVDSIWKDIPIFATPSTCIQFKPNCDQFTLD
TLPQGWREFYLHENGEIETIVKRLNSNDFLPNFHSKGY
>A0A728K9V9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGELAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A750PW70|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHYPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A379Q738|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLKTEVHRLQDTRFRPDTASEGY
>A0A291B7D7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Enterovibrio luxaltus|TrEMBL
MRIRHLFSQDNHTIRLLQITDTHLFADPHGSLLGVNTVASYKAVIGEIRDQYIVFDAIIA
TGDLSQDHSAESYQHFADGISGWIQPCYWLPGNHDCQLEMLAVLNQSTLVRCEQVLLGEH
WQMIILDSQVKGVPHGYVSNKQLMLLEQTLISQPKRHALVLLHHHPLSVGSAWLDQHQLH
NQGVFWLCIERHNNIKGIVCGHIHQALDIQYAGLRVMAAPSTCIQFLPDSDDFALDSTNP
GWREISLHQDGTIISKIGRIKGSGFHPDMNSSGY
>A0A5Q0S161|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas brassicacearum|TrEMBL
MPSVSTLTRADAALLVQLSDSHLFADADASLLGMNTRDSLRAVVDLVLKQQPDIDLMLAT
GDLSQDGTLESYAAFRQLTARIDAPARWIPGNHDEPQVMLEAAVKSTLLDPVVDIGNWRV
TMLDSAVPGSVPGFLAEEQLILLANALSEAPERHHLVCLHHHPVSVGCVWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEVDRMRERVRLLASPSTCIQFEPGSEDFAVGSQAPGYR
WLRLLPDGRLETGVERVVGFAFTPDYGSNGY
>B0UT13|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Histophilus somni (strain 2336)|TrEMBL
MISTYQYPTSEKVVRLIQITDPHLFKEKNGELLGINTYDSFNQVLSEVLQSKFDYELVLA
TGDLVQDSSEEGYQYFAESVKLLNKKVFWIPGNHDFQPKMFDVLSQYQEYIYPTKHVLVG
KNWQILMLDSQVSGVPHGYLGQYQLDWLSAKLRDYPKRHALVVLHHHIVSTNSAWLDQHN
LRNSLDLMQVLLPFRKVRGILYGHIHQAMDTKWQGYKIMATPSTCIQFKPDSNHFSLDTS
QPGWREIELYDDGRIETRVKRIQQTSFLPNMLSEGY
>A0A7U9KK98|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia liquefaciens FK01|TrEMBL
MESLFKPTVASGARVRILQITDTHLFAGENETLLGINTYRSYHAVLDAILAQQRDFDLVV
ATGDLAQDHSLAAYRHFAEGIARLPAPCVWLPGNHDFQPAMVDALADAGITPSKQVLVGD
HWQVLLLDSQVFGVPHGELSEYQLEWMERCLQAYPERYTLMLLHHHPLPSGCTWLDQHSL
RNPHMLGAVLLRYPKVNTLLCGHIHQELDLEWQGRRLLASPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRIETQVFRLENDDFRPDMDSDGY
>A0A8G0A3X5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gilliamella sp. ESL0405|TrEMBL
MKLQVSRKNYGKILHITDTHLFSDEEGCLLGINSNKSFLSVIDEIKKSKKKFDLIVATGD
FVQDGSQKAYARFAEQIIKFNTPCVWLAGNHDNYTFMQDVFAHYQLADNKIVLFGDKWLI
VLLNSQVVGHAHGFLPESELTFLQHALLQHADRHALVFLHHHPIQSGCHWLDQHTLKNSE
ALEKIIQSHTQIKAVGWGHIHQQQDHRWHHCLAFSTPSTCFQFKPACYDFQLSNDDAPGW
REITLHLDGSLTTEVHRLANNPFAPDLSQNGY
>A0A650MA70|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clostridium neonatale|TrEMBL
MIIIALLVYSILNFYVGKRVVLLLTAVFPKINNHIFWILYIMFALCIFIGYAVPRFKFTK
IAKIISGYYMSTFLYLLIIFIVLDIIRIIFGHTKFFEESILNNPKASIIIGSIIFVLVAG
IILYGNYNAKNIQIVNYDVNISRISNNHKELNVAMISDIHIGDIIGYREIEEISQKINGL
KPDIVLISGDVFDGDYYAVEDIEKIEDAFKNLNSKYGTYAVLGNHDSGSSYDKMVEFFKQ
ADIKLLQDEFLEIDDEFTVVGRKDISPIGEQGIKREDINAVLEDVNTNKPIIMLDHQPSK
INEEAEKNIDMILCGHTHKGQLFPGNLITKNLFLIDYGYLKVKNTNIIVSSGVGTWGPRM
RIGSKAEIVNIKLNY
>A0A6S7AV18|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia ultramafica|TrEMBL
MNGSRWEQITLIHLSDLHFGARHSFNAPSGGDPRSRPKLAESLLADIRDGQFALPSAFAP
SNPSAVDLAISSEAGAEPTVPRVVLAITGDFNERCVEPEFQEARSFLESFCNATIFGYTL
GPQDIFMVPGNHDLKYAEAAVEDRWSKYCLFYQDHDAKRAKANGADSQFFDPRCPHKLSR
IIDQSDQGLIVAEINSSAYVRKDTLDERRGQVDEQAIAELASQLKTIPKVQRHAAIKIAL
IHHHPVVLPALAEPDRGYDAILNSDLLLGTLKQYGFHIVLHGHKHNPHTFSYDAVCAWTT
DPVQPLVLVAGGSAGSEELPRAPSSRNTYNVISIKWHPDAGQARIHVETRGLVCFDEEGN
KLPGPEWYWKTLRLDDRLLTATTKATKSAHPTRDRDASDARYDDLRSHAIAEARRNFPAI
EVFPSLDPAQGYEASVWIEGQPHPDYVPPARVEWSASPRYFLKVYVCNRSDDPEFRVRFS
YYGPTLIQARMFWDDGHETQAYIFARYPRENPL
>A0A850L0H0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kangiellaceae bacterium|TrEMBL
MTILHISDSHLFADAEQTLLGVNTRESFEAVLDNVTRQGVEPDLIVMTGDISQDYSAKSY
QYFAERISQLNKPVFSLAGNHDELSFLKQYLCHDNLFLNKQVITEHWQVLLLNTHSKGQV
YGVVTADELTWLETCLQDNPELPTVVFMHHHPIPIDSLWLDKIGVKNAQSVTDILQAYPQ
VKLCGFGHVHQTIDVQVDNIRYLSVPSTCVQFLPQSDEFSASEERPGYRVYHCNRDGHIE
VETHRVSDYSPTVNLAISGY
>A0A427FTE6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. p106|TrEMBL
MPHPDPSQAPVCVVQLTDAHLFADPAGTLLGLRTRDSLRHVIAQVRREQPCVDLLLCTGD
LSQDGSAASYQAFRDLTGDFAVPARWLPGNHDEARVMAEVAPELVQAVTDIGAWRIIMLN
SAVQGATHGLLEPSQLSLLDDALLSAGGRHCLVCCHHQPVDIGCAWIAPIGLRNADELLR
RLEGYPQVKALLWGHIHQEWDELRGGLRLLATPSTCIQFAARSEDFKVSEEQPGYRWLRL
HADGRLETGVQRATDFEVKLDFDSPGY
>A0A4Z2HWQ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Liparis tanakae|TrEMBL
MSQRKLTRQMRLWESPEGPPPAPSLTSPVSPGDPARGHGGSALFRRLKLNRSIQERRRSS
HCIVASLCSFDSENGPSPGRSPMDSQASPGSVLHPTFPQSQRRESFLYRSDSDYDTSPKT
MSRNSSVNSEGHAEDMIVTPFAQLIKTRRLTVPSHGREDKLKAPTVPECITKETYQQMAL
ETLEELDWCLDQLETIQTHRSVSDMASTKSRLRHPGKWRKRQSIGGATAAQSGRIRPLAS
RPAEAWIDSESGGELGYGAIGRQPSLTVGLTVCRWARRGQSAPAAPTLTPLPCSFAPPLW
AAVTLECPGVTACGLSSRTLTTPSCHWGTRSAPAPLHYHTACLCHRPKPPATLNMGVVEA
VDPAPSPCPSPVPGGYRLPRSSSYSPLQGRAGAELDLDAAAGGVLEGSGTAAERRTPLVD
LFCETCSRPWLIGWWDQVGLGELAEGKRGLAVAILDSTYGERQAGWDGWKKRERENWEVK
E
>A0A2I3HQY1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nomascus leucogenys|TrEMBL
METLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERD
LSPRPGLRKSRLSWPISSCRRFDLENGLSCGRRALDPQSSPGLGRVMQAPVPHSQRRESF
LYRSDSDYELSPKAMSRNSSVASDLHGEDMIVTPFAQVLASLRTVRSNVAALARLQCLGA
AKQGPVGNPSSSNQPPPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKR
ILNRELTHLSETSRSGNQVSEYISRTFLDQQTEVELPKVTTEEAPQPMSRISGLHGLCHS
ASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIMFSIFQSELA
LMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLL
ADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEF
FQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLE
DNREWYQSKIPRSPSDLTNPERDGPDRFQFELTLEEAEEEDEEEEEEEEETALDKEALEL
PDTELLSPEAGPDPGDLPLDNQRT
>A0A6P0PB73|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Okeania sp. SIO2F5|TrEMBL
MIFQPPVLVAQITDTHLFADSIQGKMYGVPTERSFVKVLEKLKQLQPQPDVLLLTGDLSQ
DETSQSYQRLASLLSPLNIPTYWIAGNHDNLPTMERVLSSAPISAKKSFEMGGWNFFLLN
TNVPGCVYGEISPESLEWLEYNIKMTGNKPVLIALHHPPVKINSEWMDKILLHNPENFLS
IINRYPQVKIVLSGHIHQEFAKEINGIHYLSTPSTCIQFEPGNYKFFLDKQPPGLRLLTL
YPDGNYTTKIERINYIYECDMAASGY
>A0A0S7M5C0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
DQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIASTFLEKQHDLEILS
PLAKEKEKKKRPMSQISGVKKATQSPSLAPACIPRFGVNTPHESMLAKEIEDLNRWGMDI
FKLAEYSGNRPLTVMMYSIFQERDLLKTFKVPIDTFLTFMMTLEDHYHADVAYHNNIHAA
DVVQSTHVLLSTPALEAVFTDLEIMAALFASAIHDVDHPGVTNQFLINTSSELALMYNDS
SVLENHHLAVGFKLLQEENCDIFQNL
>A0A0S7HFM2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
MLNRELNHLSEMSRSGNQVSEYISNTFLDKQNELELPCPVQKVRKRKQNQQQQQQQVGMM
TQISGVKKVNHTSSILGNVGNRFGVKTDQEELLSKDLEDINKWGLNIFKVTEHSHNRPLT
CVMYKIFQVSFCLLLEG
>F7RIS5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. HN-41|TrEMBL
MLKEAVSYSIAEEESVRIVQVTDPHLFADPEAQLLGVNTGKSFAAVLNTIRAVDYPAHLM
LATGDLSQDYSAESYRQFVTAVTPLNLPCHYLPGNHDDPRIMFLHMQGEQIFGQQRILAG
KWQILMLDSTVRGKPGGSMAESQFELIKQAITTHPEYHTLLVMHHNPILVNCTWLDQHCM
DNGAEFLRRVSVYPQVKGLLWGHVHQSIDTHYDGPHGALKLMATPSTCIQFKPLSPYFAL
DGLQPGYRLLELKPDGSISTNVYRVPGNHFSPDKDSSGY
>A0A625SZ60|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica I|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRSDTASEGY
>A0A3U3ISL2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica I|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADVPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5H7G318|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Meleagridis|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPHVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A3X9HWK5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica I|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFCAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A509E2Z8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Thalassocella blandensis|TrEMBL
MKSTIKILVVSDLHAVIGDGISDDSRLLFIDGSSEYGDGFIKYAKSVAKDLDLLICSGDI
SNKGNTESFKQGWLFLNKVKAELNIKNMLCVPGNHDHQSRKTNGVFDPKHHLQFITPPFP
FEQENLNTHFWSWHWSHSSNESDSFNAISLNTSAYHGYGDEFQYGRIATEVVDQIHTYIC
SDSFPKRDFNLLVCHHHPEKMDYVDTNYDSEAMEGGSYLIRKIDEVDKGPWLIIHGHKHF
PDIVHSRSAKTFGPVIFSAGSMSAKIYPPNKLKTSNQFYIIEVDIIKTSEQGSLAGTFRS
YEWNYSDGWKPSGRECLPSEGGFGSIVPPKILASKILNEINDDTPFLDTNDLTKFENDLK
YLTPSDLKDLISKIDESDFKVLLENNKIVQIGRKA
>A0A0A2YZ28|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gallibacterium anatis IPDH697-78|TrEMBL
MSDLFRDESAGVIKLLQVTDPHLFADEDGELLGINTFDSFRQVLSEIKKSGFESNYILAT
GDFVQDNSEAGYHRFVKEIVQLGKKIFWIPGNHDFQPKMEAVFDLYKAVIQPEKHLLLGE
SWQVILLDSQLYGVPHGMLSEEELKWLEQRLSLYPDRNTLIVLHHHLLPTNSAWLDQHNL
RNPYDFSEILAKHKNIKAIVYGHIHQEVNAVWQGIPVFATPSTCIQFKPDCAYFTLDNLQ
PGWREISLYPDGRLETKVHRIKDKVFLPKDNMNGY
>A0A8G9I3P7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDIHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A539CSS8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Beijerinckiaceae bacterium|TrEMBL
MAHKSIETKHYEERASFFDDLTRMGQLSRRGFLHIAGVSAGIAAAKGLIVPQSFQLIEIA
QAAETATPAFTIAYVSDTHLYTRNVNDRFIRSAVKAVEDVNALDPQPDFVLFGGDLAQLG
RREELDLGAQILKDLKAPVKMMVGEHDWFLDMGEHWQALFGPPQYSFDHKGVHFVTLMSV
QEKDFWTARGMTPEERMHTVAGLDNGIQSRFEVGPDGRQWLQNDLAGVDKATPIVIFSHS
PLYKYYRNWNFWTEDADEVQAILSKFDTVSVIHGHTHQLLLNHIGNIDFYGLLSTAWPWP
YAPEGLPKLTVQMNRADPFNAFDGCGDGQLNVLASGMIDKVYNLWNRNPVTVRASYLSSS
GAKDRPPATTLSSY
>A0A2W5E4U3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella oneidensis|TrEMBL
MLKEAISYSVADESVRIVQVTDPHLFADPEAQLLGVNTSKSLAAVLNTIRAVNYPAHLML
ATGDLSQDYSPESYRQFVSAVAPLNLPCHYLPGNHDDPRIMFLHMQGERIFGQQRILVGK
WQILMLDSTVRGKPGGHMAASQFELIEQAIAAHPDRHTLLVMHHNPILVNCAWLDQHCMD
NGTEFLKCVAQYPQVKALLWGHVHQQLDSLYDGPHGALQLMATPSTCIQFKPQSPYFALD
GLQPGYRLLELKADGSISTNVYRVPGNLFSPDKDSSGY
>A0A198H0M4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter soli ATCC BAA-2102|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLGAIHAENRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFNVPCVWLPGNHDFQPAMYSALQEAGISPAKTVIVGD
QWQILLLDSQVFGVPHGELSEFQLEWLEKKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLVKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGVLTTEVCRLSGLKFRPDTASEGY
>A0A377HJF0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Grimontia hollisae|TrEMBL
MRISHQPSQYSQTVRLLQITDTHLFADPYGSLLGVKTAASFQAVVENIQSLGVEFDAMIA
TGDISQDHTAESYQRFVDGISHWTQPCFWLPGNHDFQPEMQAVLAQSPLQRSDVVLMGEH
WQLVILDSQVKGVPHGRLSEAQLALLDLALVTHSERYTLVLLHHHPLPAGSAWLDQHQLH
NRDEFWTVVDRHTNVKGVVCGHIHQALDTHYKGCRVMAAPSTCIQFKPDSDDFALDTTNP
GWREIELHHDGTISSYVGRLKGTDFQPDMNSSGY
>A0A8I0VNY2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fulva|TrEMBL
MPHSNPAGTVNVVHLTDAHLFASPEGSMLGLNTRDSLRHVVRQALREQSDTHLLLCTGDL
SQDASVASYAAFEQLTAGFAAPARWLPGNHDEAQVMAQVAPELVQPVTDIGPWRIVMLDT
AVPGAAHGWLQDTQLSLLETALRTSGERHCLVCLHHQPVDIGCAWIAPIGLRNADALFAV
IDRHPQVRALLWGHVHQEWDQWRGDLRLLATPSTCIQFAPGSEDFEVSQQHPGYRWIRLQ
TDGTVDTGVERALDFEVRLDFDSPGY
>A0A844X786|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gilliamella sp. Lep-s5|TrEMBL
MESFLKLPILNKNYGKILHITDTHLFSNDDSSLLGVNSNASFLSVINEITRSNKKFDLIV
ASGDFVQDGSKKAYARFAEQINKFNTPCVWLAGNHDNYAYMQDVFANYQLADNKVVQLGS
NWLIVLLNSQVVGQAYGLLPESELDFLQNVLIKYSSRNVLVFLHHHPINSGCHWLDQHIL
KNSDQLEQIVKQHVNIKGIGWGHIHQKQDYVWHHCKAFATPSTCFQFKPECYDFQLSSED
APGWREITLNTDGSIESDVYRLTDNQFLPDVSQNGY
>A0A8C4PDB5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dromaius novaehollandiae|TrEMBL
MTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQ
VLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITGALSEH
>A0A6S7DCZ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter dolens|TrEMBL
MTRILQLSDTHFGTERKPVVEAALDLARALAPDLVVISGDITQRARRGQFAAARKFIERL
SLPVLAVPGNHDIPLFNVFARALNPYGNYKRALGAVLEPVYETAGLLAIGVNTTRPRRRK
DGEISDAQIARVAQRLRQARPGQLRVVVAHHPVRAKVESDRFNLLIGRERALAAWAQAGV
DLILGGHIHLPYVLPASADPGVMAGWAVQAGTACSRRVRGNIPNSVNVITREGEGETRVC
HVERWDYAAGAHAFAPVDKTLVAG
>A0A502IVL0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus haemolyticus|TrEMBL
MKNTFVYQTEKSIIKLLQITDPHLFKEKETALLGVNTQASFTQVLKEIQQENNTFDIILA
TGDLVQDGSDEGYRRFVEMVTPLNKPIFWIPGNHDFQPKMVEHLNKTPMESAKHLLLGKY
WQVLLLDSQVYGVPHGQLSQHQLNLLEEKLAQHPNRYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLGKFSNVKGILYGHIHQEVNAIWNGYQVMATPATSIQFKPDSHHFTLDNLQP
GWREIELHENGSIYTQVKRIQEAQFLPNMQEEGY
>A0A5C1AL86|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Limnoglobus roseus|TrEMBL
MNPSRRTFLAASSAALAVTAPTARAAADGPFQFRSPPVLTNPTPDGVTVLWATSGPATGW
IEYGETERLGSKAGGATDGLMPFDERVFKVRLAGLKPGCRYFYRVHAVRIDFRGPYDIRR
VGTDAVASEVYRFTTPPADPAEVRFTVWNDTHEVADTLKALHTAHQKEPGDFLLWNGDQT
NDITTEERMVAQFLAPAGQPFAATVPYYYVRGNHDVRGPGARHLPRFTDGPLYYSFRRGP
MAALVLDTGEDKPDDHPVYGGLNDFAAFRTLQAEWLAKEIEKPEFQSARFKVLFCHIPLW
WKREKNTGDFCGDGRAKWHDLLVKAGVQLVVSGHTHEPAWLPAEKGRPYGQLIGGGPKPT
AATYLRGHATRDGLTVTQFKLTGEVQYTVKIG
>A0A7X3M6Y4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. Taur|TrEMBL
MDSLLTLPAANGADIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIMAQQRDYDLII
ATGDLAQDHTVEAYQHFVAGISRLPKPCVWLPGNHDFQPAMVNTLADAGIASDKHVLLGE
HWQLVLLDSQVFGVPHGMLSEYQLEWLDKALRLHPERHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLQHFPRARNLVCGHIHQELDLDWHGRRVLASPSTCVQFKPHCTNFTIDNVA
PGWRWLTLKADGLLETEVNRLQSDLFRPDLDSEGY
>A0A5B2UTT4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas brenneri|TrEMBL
MPSVSTVNPDAPALLVQLSDSHLFAEADGTLLGMNTRDSLQRVIELVRARQPQIDLLLAT
GDLSQDGTLESYQLFRDLTQPIGAPARWIPGNHDEPQIMAQATMGSALLESVVDVGNWRI
TLLDSAVPGSVPGYLAEPQLQLLAQALSEAPGRHHLVCFHHHPVPIGSAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEEAPGYR
WLRLHPDGRLETGVERVQGFAFTVDYGSTGY
>A0A0A8F919|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dickeya zeae EC1|TrEMBL
MESLLTLPVACGARVRILQITDTHLFADEQGTLLGVNTNRSYQAVLNAIAAQQMNVDLIT
ATGDLAQDHTQDAYTHFATGIRRLGAPCVWLPGNHDFQPAMVDVLARSGIAPSKHVLLGE
HWQVILLDSQVFGVPHGELSEYQLEWLDRSLQSQPERHTLLMLHHHPLSSGCTWLDQHSL
RNAHSLDALLSRFPHVRTVLCGHIHQEMDLDWNGRRLLATPSTCVQFKPHCTNFTIDNVA
PGWRYLELLPDGGVETRVCRLEGNEFLPDMDSDGY
>A0A5Q0GEJ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anabaena sp. YBS01|TrEMBL
MNEKLPISIAQITDIHLLASESQRLQGISTIESFLAVMKRLEELRPELDLLLMTGDLSED
GTPESYENLQHYLNSLQIAAYWLPGNHDCAIAMDKILNLGMVSRRKSFQRGNWNFILLNS
SIPDCVYGYLSATTLDWLDSELRMLPNNPTLIALHHPPVSVNSAWIDGSCLRNSQELFAV
IDRYPQVKLVLFGHIHQEFRHQRHNVHYLGSPSTCYQFQSQSPIFAINQELPGFRLLKLY
ADGTWTTKIERVPYSLPIESAVTVSY
>A0A7W3DV72|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. RHBSTW-00013|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRAKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A220W6W7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sphingorhabdus sp. SMR4y|TrEMBL
MLMAQITDIHLGFDPDNPAEFNRKRLDQAIKAICAMTPQPDLLLATGDLVDRGDQESYQR
LQNALSVVPFPVHMCLGNHDLRAPFHKQFPDVPVPDGFVQYEVDTPELRLLFLDTLEEGR
HGGAFCETRAAWLSARLSEQPDKPVILILHHPPVESGIEWMTTHPEEPWVSRLAETVAGH
DQVKGMITGHLHRNISTWWGDISLAICASTAPQVALDLSPIDPDVPDGRNMIVADPPAIA
LHYWNGRQLVSHFENAEEHVMLARYDENLQPLVRALLAERPQ
>A0A8F8D0H9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter haemolyticus|TrEMBL
MTYQVSTSSQQDFVMIQITDTHLLEYPHLEFVGMQPEQSFHAVIDLMRQQHPQIDLIVHT
GDLAQTPTPVTYNRYIQHMQSLEIPFFHTPGNHDDVAHFPFHEVDQTQLTVIELGKWVII
LLNSAQPQRIDGRITESQLKQLHTLLSKLHDRYVILACHHHPFAMQSAWIDQHKLKNASD
LLETVKPFSNIKAIVCGHVHQDAIHQWQGIEFLSTPSTCIQFKPKSEKFALDEEHPGYRY
ICLKANGELETQVYRLKTSERMSSSEVLGYD
>A0A731C3K4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella oranienberg|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTPGWRT
LELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A7T8INL2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella algae|TrEMBL
MLKEAITYSIPEDKSVRLVQITDPHLFADPEGQLLGVNTANSLNAVINTIQAVKYPADML
LASGDISQDYSGESYRNFVEAIKPLNLPCHYLPGNHDDPRIMYLHMQGERVYGHRRVLAG
NWQIILLDSTVRGKPGGHMAESEIEIIRSAIAAEPDKHVLLVMHHNPVLVDCTWLDQHCM
DNGAHFLKEMGRYPQIKGMLWGHVHQQLDTEYQGETHKLSLMATPSTCIQFKPLSSYFAL
DALQPGYRLLELKPDGSMLTNVYRIPGERFAPDAEASGY
>A0A8G1JXR3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. 3-2|TrEMBL
MPSVSTLTTADTALLVQLSDSHLFAEADGALLGMNTRESLQKVIELVLEQQPRIDLIVAS
GDLSQDGTLESYQQFRQMTAQIDAPARWIPGNHDEPQIMAQATVKSALLESVVDVGNWRV
TLLDSAVPGSVPGYLQDHQLQLLAGSLSEAPDRHHLVCFHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQARAVLWGHVHQEIDRERNGVRLIASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGRLETGVERVTGFDFQVDYGSNGY
>A0A7J0AT87|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MQNKLKILLLSDIHFLSLPAEHDSHAQVRRAFLQDIEGYKLVNGAFDVILVSGDIAYKGV
ESEYDKALTFFHQLCDVSGCAYERIYVVPGNHDKNLNAVRAELRHLINQGLSSEKADHEH
SSKLYLNLLIRDKEACKALYSPFREYAEFAIKMDCCDSIMCKLTSSEDSVFDEENDKAYY
KQEIGVLNEYPVVLYGFNTCLNSDWFDEDDHGLGHKLFLPMLGYHALVDISGTINIAMMH
HPLDRIVHSESISTFMDKHYPIQIFGHLHKPVCWEDKCLHIQSGALQPQTSSEGGDEYFS
VYNILELNVTSDENGKDFLQANLSVQRYRPESEGFETLDSEGHSFKTQLHRTPSRWSNDN
KQKSLTERLPPDVSKRQIRLRFLNFHDQKSVIKRMNIYTYNDNISLHENCFHFLETVDNQ
HKYATLWSLVK
>A0A068R914|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus poinarii G6|TrEMBL
MESLLEVPVAEGATARILQITDTHLFANQSDSLLGVNTYRSYHAVLDMILAQNLDIDLIV
ATGDLVQDQSINAYQHFAEGIARLPAPCVWLPGNHDYQPAMVDTLAAAGISPSKQIFIGQ
HWQLIMLDSQVQGVPHGELTDYQLEWMKKCLDEHRERHTVVLLHHHPLPSGCTWLDQHSL
RNAPELSACLKGRTQVKAILCGHIHQEVDDMWKGIRVMATPSTCVQFKPHCTNFMLDTMA
PGWRYLELSVAGNKEAKLQTQVHRLKSNEFCPDLDSDGY
>A0A2U1TUP8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Brenneria roseae subsp. americana|TrEMBL
MESLLTLPVASGARIRILQITDTHLFAGEHETLLGINTYRSYHAVLDAIQAQQEAFDLIV
ATGDLAQDHSLEAYHHFSRGIRQLDAPCVWLPGNHDFQPAMVDALAEADIAPSKQVLVGD
KWQIILLDSQVFGVPHGELSDYQLEWLERCLKNQPERFTLLLLHHHPSPSGCTWLDQHSL
RNAHSLAAVLARYPQVNTILCGHIHQEMDLDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLMPDGRLETEVFRLSGSEFLPDMDSDGY
>I2UD72|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli 4.0522|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYRHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7Z2ZDS6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. gcc21|TrEMBL
MPPVTTTEAGYVSIVQLTDSHLFADHSARLLGLDTFASLNAVIDQVLDEVDQMDLVLATG
DITQDGSEGGYQRFIEAIGRLPAACRWIPGNHDDAALMATLGDASGLNADWIDLANWRIV
LLDSSIPGAVPGRLDAEQLDHLDAALASAGERHVLVCLHHHPIDIESDWMNPLGLQNADE
FLQRVDSNANIRGLLWGHIHQQLDAMRGKVRLLATPSTCIQFDAHSADFATDTQSPGYRW
LRLHTDGSIETEVSRLPAGRFVPDPDASGY
>A0A6J5B4B7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia phenoliruptrix|TrEMBL
MLLAQISDLHIKRPGALAYRRVDTAAYLERCVAALNALDPRPDAVIMTGDLVDQGEPQQY
EHLKALLAPLEIPYFLLVGNHDDRAALRAAFPDRAELQGGGEFVHYALDVGPLRLIALDS
MVPGHSAGTLCDARLAWLAARLDAAGGKPTVVALHHPPFACGIGHMDKLRLDPTAAERLT
ALIARYPNVERVICGHVHRPMFVRFGGTIASAIPAPAHQVALDLRDDAPSAFMMEPPAYA
LHRYEPGVGIVTHHAYVDAAEGPYPFYEPEGVLID
>A0A0K2TVV5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lepeophtheirus salmonis|TrEMBL
GTPSNGRNGSSRRCSGSGRLLSANISGFSNRSSGDAKAGESLIPPASSIQGNSSSALGTI
WRQSECINYRNFRLRRPKIRAIVALPKHSPQYNAAKWALERLGVESVLTFSTETAIQALN
NGLSSTPHLVLLDSRHPRNIDAEALAKHVRQSPYGNNIVVVGVVKKSFIEHEEVIVASHL
RAGFDRVLIDSGSRGYWMNELVLLLHNDVDTNIKLNCSESVLTALESCQDIVQITDKQNR
LIYGNPTAQKVLGFSQEELNNKCIWDYQSTKQNSNPISCDSSSSSSNNLLPTKSTLEPPL
SDDADDVIKQKLDTGKVWEGPLNCRRKSGDYLALDTKIIPISFSSRRNSDHVIYVRKTPN
LSVPPIPSSSSAIVNNYNTMNNTKSSSCSNNTNNNHSNSSSCQISQHHLKHLSSTAHSSK
ALKQQLHENHCTEVVSTSMASGNYYSGRRQSGSILPGMSIEAPITKIINIILSVQEKSPA
SIVSELDKVIEILQATTGTTDLFSPELSKDGIKKRPDPVATDLLGALLSNSTRDALTQRR
GSTDPVAVSNTKNTSIHRTSLPNFDNSPVATRHLLENSSKWEFNILELEKLTNKRCLVWL
GMTVFLRFQIHKTLNCSESTLQNWLTLIEANYNADISYHNSTHAADVLHAVAYFLESPRV
KEYCDGVDEAICLIAAVIHDVDHPGRNSAFLCNSGNGLANLYNDITVLENHHASLGFKLT
QSDKRVNIFQNLDKDSYKLIRQGVIDLVLATDMSKHFVHVNKFASVFNTIESGECSVSDV
VATDGSDAVLSGVPNTPENVAILKRMLIKCADVANPARPLHICKVWAFRIAEEYFSQTDD
EKRLGLTVVMPQFDRATCSITKSQIGFYDFFINDMFDCLNNFDDFHKLVDIIQFNYNYWK
QEAEEEENAKDLQSEEEVKSSNRSKSASEKEDIREEDEDIPT
>A0A7L1E704|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oenanthe oenanthe|TrEMBL
EEAYQKLASETMEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQV
SEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTD
QEDVLAKELEDLNKWGLQVFRVAELSGNRPLTVIMHTIFQASSSSPAAFFLILEIERDLL
KTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILA
AIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNL
TKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVRKC
M
>A0A2N7DM41|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. 10N.286.48.B5|TrEMBL
MLKEPVSYPIAETDVVRLIQVTDPHLFADPEAQLLGVNTAASFQAVLDIFLASDQQADIM
LASGDISQDYSPQSYQHFSNAVTKLDMPCHYLPGNHDDPRLMSLHMQGKQLFGQQRIIIG
NWQILMLDSTVRGKPGGFMAEDQFKLIDAAIKADPEKHVLLVMHHNPILVQCSWLDQHCM
INGDNFLQRMGEYPQVKAALWGHVHQAIDSEHQGANGAIHLMATPSTCIQFKPKSSYFAL
DGLQPGYRLLELASNGSIHTNVYRVPGENFSPDNDASGY
>A0A522EMK0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylovulum sp|TrEMBL
MTNLPACLPSDCLSILQITDLHILASQDATLLGLNTAYYFDAVLALAFAGHRSFDLILLT
GDLAQDPVIESYQYILDKLTALDIPCLCLPGNHDDDALMQQVFNTRLINCRKHLVLNDWQ
IIVLNSQIPGADGGRLAAAELAYLEDCLQANLDKYALIAVHHHCLKTDSIWMDTMMIENS
GEFLAVIGKYPRAKLIVNGHIHQEMDKTTGAVRVLGTPSTCFQFKPGSREFSLDDTSPAY
RLIQLHADGHIATEITRLPGRLVGLQTDTEGY
>A0A5I3I9A1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Nima|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2N1DRN6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Psychromonas sp. MB-3u-54|TrEMBL
MKVMSIQAAKLRSDQQGCLQLLQITDTHLFSDRNKDLLGIKPAESYEAVIKHAARYSSKC
QAVLSTGDLSQDHSQQSYLDFTKQIKTLNLPCYWLPGNHDMQSVMLPSFLQEGLAQSKQI
VSDFWQIILLDSQVEGAPHGFLTEQQLNFLQQALSDHPDKHTLICVHHHVLPVKSAWLDQ
HILKNNQQFLELIKLHKNVRAVLSGHVHQAGDIEFNQVRFLTSPSTCLQFKPNSEDFDVD
DSAPGYRYLALHKNGTLMTKVERIAHGAFSPNKEATGY
>A0A5E4I212|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKILAIADLHADEDALDRLRVLAGKNPYDAVLVAGDITNNGPVSYASDLLELFPHALCVH
GNMDPPQVSTLLSQRGCNLHGRRIPFGPKKEWNIVGLGGSNPTPFHTPSENSDEEISKIL
SNTGMDEFSIFLSHPPPFGAFDTVAGGMHVGSKAVLSAIEKHKPLLCICAHIHEHEGQQV
LGETLVVKLPPALKLRAAEITIGENLEANFISFE
>A0A5E4LQ66|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKPSVWPDQHDDMLNQKLFLVFLIISLLIIVDALVIEPYNPVLVKQNFDILEGDQNIKII
FISDIHAGYQTTQYLETVVEKINQQEPDVILLGGDFIDHENELELLAPLKKLQSRYGTYA
VLGNHDYGSWMCGGDGWLGDKVEQKLSSLGVDVLRNENRILEIHGEKFAIIGLDEFWMCR
NNYQNASMGTDNLPKIILTHNQMGVDQTKVDGRNVVLSGHTHCGQIRIPFITDLYLLPVF
GKAGGLYQQGDSSLYVSCGVTSGRIRFLAPPEIDLMDVH
>A0A1A7X9P0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Iconisemion striatum|TrEMBL
MSSNELSVEMDSCIRTFKEHMHLELEPPKMPGMMGGKRGATSPKLSPRSSPRLFRKLMVN
KSIRQRRRFTVAHTCFDVENGPSASCSPLDPQASPGSGLVLHTNFPGHNQRRESFLYRSD
SDYELSPKSMSRNSSIASELHGDDLIVTPFAQVLASLRSVRNNFTILTNVQCPSSKRSPA
ATTQPPITKVCLPDEAYQKLAMETMEELD
>A0A452S697|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ursus americanus|TrEMBL
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQ
KDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIF
NVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAAD
VAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDES
VLENHHLAVGFKLLQEEHCDIFQNLTKRQRQTLRKMVIDMVLATDMSKHMSLLADLKTMV
ETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKE
RERGMEISPMCDKHTASVEKSQVSNMKFSKFLCSYRTTPL
>A0A344KFM6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio campbellii|TrEMBL
MQSSSDSIKLLQITDTHLFEADEGSLLSVRTADSFAAVVQEILNHQVQYEYILATGDISQ
DHSAESYQRFAEGIAPLKKDCFWLPGNHDYKPNMGSVLPSPQIQAAEHVMLGEHWQLVLL
DSQVVGVPHGRLSDQQLALLEEKLAENPQRHTLVLLHHHPLLVGSAWLDQHALKDADAFW
QVVGRFENVKGILCGHVHQDMNVLYNGIRVMATPSTCVQFKPDSDDFALDTESPGWRELE
LHSNGDITTEVNRLPDGQFQPDFNSNGY
>A0A1I3RDP8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus mauleonii|TrEMBL
MESRLEIPVAEGATARILQITDTHLFANERDSLLGVNTYRSYHAVLDMILEQNLDIDLIV
ATGDLVQDQSINAYQLFAEGIARLPAPCVWLPGNHDYQPAMVDTLAAAGISPSKQIFIGQ
HWQLIMLDSQVQGVPHGELTEYQLEWMEKCLDEHSERHAIVMLHHHPLPSGCTWLDQHSL
RNAPELSEYLKGKTQVKGILCGHIHQEVDKMWNGIRVLATPSTCVQFKPHCTNFMLDTVA
PGWRYLELSVAGNQDAILKTQVHRLKSNEFCPDLDSDGY
>A0A5C7VWN0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas alcaligenes|TrEMBL
MLLVQLSDSHLFAEEDGKLLGMDTCDSLAKVIERVQTEQPQIDLILASGDLSQDGSLASY
RRFRDLSAQLNAPTRWFPGNHDELPAMQQACAGSDLLQPVVDLGHWRIILLDSSIPGAVP
GYLADDQLQLLERALSEAPERHHLVCFHHHPVSIGCRWMEPIGLRNPDALFAVLERHPQV
RAVLWGHIHQEFDQQRGGIRLLASPSTCVQFAPGSEEFQVDTTAPGYRWLRLHADGRLET
GVSRVTGIHFEVDYSVKGY
>A0A6C8MHY4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. arizonae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYGALQEAGISPAKHVLIGE
EWQILLLDSQVFGVPHGELSEFQLEWLERKLANAPERQTLLLLHHHPLPAGCSWLDQHCL
RNAAELDSLLAHFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A7Y4FMB5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio tubiashii|TrEMBL
MKVTSSSSNSDSIKLLQITDTHLFEPVDGSLLSVNTLDSFNAVVAAIVEENQSFDAVIST
GDISQDHTAESYQRFEQGIAPLKNTCFWLPGNHDFKPSMNSVLPSTQIKQVEHVLLGEHW
QMVLLDSQVVGVPHGRLSDQQLALLEDKLSQYPQRHTLVLLHHHPILVGSRWLDQHTLKD
AHHFWEVVEKYSNVKAVLCGHVHQDMNVLHQGVRVMATPSTCVQFKPNSDDFALDTLSPG
WRELELHSDGQLTTQVKRLPYGSFQPDFNSAGY
>A0A1V3HC09|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salinivibrio sp. MA351|TrEMBL
MQPCQIDNAHGDCIRLLQITDTHLFADEQGSLLGINTLQSYHAVLEAISATSKPFDAIIA
TGDLSQDHSALSYRRFVDGIQRWKQPCFWLPGNHDFQPEMRAVLHSNTLMARSQVLLGEH
WQMILLDSQVAGVPHGELSHDQLKRLDADLSAYPERHALVLLHHHPLEAGSTWLDQHKLV
NREAFWQIMARHPQAKVVVCGHIHQALDIRHQGARVMAAPSTCIQFMPDSHDFALDNQNP
GWRWLTLYPDGHIDTQVERVTGRYFRPDFDSSGY
>A0A7V5H698|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacteroidetes bacterium|TrEMBL
PLVILQLTDLHFLAESGQTMASVDTELSFRQTLEYAQSKQGKADLILVTGDLAQDPCLSS
YQRIVKELEKYKTRTVCLPGNHDDLALMQQLISDKQVNCEKHLKYKHWQVISLNSKKPGS
QGGYLASDELDYLADILNKQADLNTLIAVHHHPVPTNSPWMDKMMIENGEDLFSLLKKYP
QVKAIICGHIHQELVIHKNNTMILGTPSTCFQFKPLCTEYTLDSRQPGYRILQLFPNGSI
KSNVYRLPFGLGGFPK
>A0A2U3B5B2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio albus|TrEMBL
MLTSSTAYTYAGEPGILERKTEDTESQSIKLLQITDTHLFSTSDGCLLSVNTLDSFHAII
EEINNQQIPFDGIIATGDISQDHSERSYQRFEQGIASLEKPCYWLPGNHDYKPGMQSVLP
SPQIQTNTHVLLGEHWQMILLDSQVEGVPHGKLSEEQLTYLDDKLAEYSNRHTLVLLHHH
SVLVGSSWLDQHTLYEPEKFWQIIEKHNNVSAVLCGHVHQEYDSMHAGVRVMASPSTCVQ
FKPDSTDFALDPLSPGWRTLELLKDGSVATQVYRLGDGRFHPDFSASGY
>A0A7Y1MKQ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas gessardii|TrEMBL
MPSVSTVNPDVPVLLVQLSDSHLFAEAGGTLLGMNTRDSLQRVIDLVLAQQPRIDLLLAT
GDLSQDGTLESYQQFRDLSQQIGAPARWIPGNHDEPQVMAQATMGSALLEPVVDVGNWRV
ILLDSAVPGSVPGYLADVQLQRLAQALSEAPGRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERQGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERVQGFVFTVDYGSNGY
>A0A7C1P0G1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Porticoccus sp|TrEMBL
MRIELDNKQQPIQVIQITDTHLGDQPGEPLLGMDTDQSLGHVLDLIRKERKPADLMLATG
DISNCGSVASYQRFHQLTQHLAPRALWLPGNHDSLPAMQQAMAGAEELNRCAEVGDWQIV
MLDSTTPGEVGGNFSADELAFLRQTLQDSTASHVLICLHHHPVIIGCDWLDQQQVANADD
FFAIIDEFDSVRGLLWGHIHQPIDQQRKGVRLMATPSSCVQFAANSPGFKLARLNPGYRW
LELHADGRIDTAVSRVTGVEFDIDYQCSSGY
>B1LF26|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli (strain SMS-3-5 / SECEC)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A1B6CR72|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clastoptera arizonana|TrEMBL
RTDVLVRDEDCDTQVNELAAESNCEPLCHRLQQIKTNSPKQHAFRVLLVFAKDDSACSTL
SGASEHLGFSREVASTLEQALELYQAHSSPPQIVFIDMRFSWFHGEKICRSLRAVKKSNH
VIFVAICKKNVVDKDEKELRSALKLGFNRVLVEPLSITQCVCELVQLAHGQLDLHSILAQ
NEAIYLALDKSRDLVLVTDSLHVIQYVNRTWCQVLGYKSEDLIGRSLHSFHQLGNMDPVT
RQLEKGFDWEGKISWRSKSGENITLQCRAMPYQAIGSEPTHYVYVQDNPLENHIYPRGSI
PSIRKGSYDLKSINSEGAQSARRQSLAKLHNLPLEAPITRVISLICAAQENSTGQVVQIL
DKVVDILRTTELYSSHLKADNLRCEDPVTSDLIGALITVSKLSHQGPVPVSTTRRSSNDS
AAVKAQQAGLSGNKPIFSMSASPQLKELLDTSLQWDFNIFKLEEITGKRPLVYLGMNLLM
HFDVHKTLGCDEKTLYNWLTVIERNYHLSNTYHNSTHAADVLQAMAGFLEKERIKRLVDE
LDEACCLIAAATHDIDHPGKSSAFLCNAGNELALLYNDVSVLESHHAALTFKLTLRDDRV
NIFKGLERDTYKVARQSIIDMILATEMTKHFEHLAKFVSVFNKPSPTSEDGNCDNRVS
>A0A7I6PRC7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sp. WP2-W18-CRE-05|TrEMBL
METELPQAPDGSVRLLQITDTHLFASAEGRLLAVPTAQSLAAVLERVQANEHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGDHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHHGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRVASQVWRLPLGQFVPDPNATGY
>A0A2G8D6H4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia sp. OLMDLW33|TrEMBL
MDSLLKLPVASGSRVRILQITDTHLFAGKHETLLGVNTWASYDAVLEAIAAGQRHYDLIV
ATGDLAQDHSVEAYQHFAEGIARLPAPCVWLPGNHDFQPAMFSTLAESSIADEKQVLVGD
RWQIVLLDSQVFGVPHGELSDYQLEWLERALAAEPQRHTLVLLHHHPLPSGCSWLDQHSL
RNPHMLDAVLQRYPLAKTLLCGHIHQELDLDWHGRRVLASPSTCVQFKPHCTNFTIDAEA
PGWRWLDLYDDGRLETEVQRLATRKFNPDLDSEGY
>S3EI09|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Photodesmus katoptron Akat1|TrEMBL
MVLRLSLNLTNSSSIKLLQITDTHLFAPEDGSLLNVITLDSFQAVLGAIIEKKFQFDVIV
ATGDISQDHSEESYQHFVDSISVLKQPCFWLAGNHDYKPSMAGFFRPKKIFNLEHAFLSE
NWQIIILDSQVFGVSYGHLSKQQMLLLDSILREYHHHHTLILLHHHPILVGSDWLDRHAL
KDSIEFWQILRKYSNVKAILCGHVHQNIDRDIQNIRVLSAPSTCIQFKPNSKHFALDRLS
PGWREIELYDDGSISTQVHRLMSTYFLPDLNTNGY
>A0A0J5P3Q4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribacter muris|TrEMBL
MDSVYHFPYSTPVVRILQITDPHLFALDNGQLIGVNTSQSFQAVLDAIQQTAFDYDFVLA
TGDLVQDHNREAYHRFAKMVKPLQKPIFWVEGNHDIQPQMRNALAMYAQMQMAKHILAGD
KWQIILLNSQIHGLPKGELAQDQLAFLTAKLTAYPNRYSLVVLHHNILPTQSAWLDQHSL
ANADELATVLAPFQNVKAILHGHIHQEVDAQWHGYRVLATPSTCIQFKPNCDTFTLDAVP
QGWRELNLMPDGSIETIVKRLDCVKFLPNFAAQGY
>A0A4Y9JQZ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribacter muris|TrEMBL
MDSVYHFPYSTPVVRILQITDPHLFALDNGQLLGVNTSQSFQAVLDAIQQTAFDYDFVLA
TGDLVQDHNREAYHRFAKMVKPLQKPIFWVEGNHDIQPQMRNALAMYAQMQMAKHILAGD
KWQIILLNSQIHGLPKGELAQDQLAFLNAKLTAYPNRYSLVVLHHNVLPTQSAWLDQHSL
ANADELAAVLAPFQNVKAILHGHIHQEVDAQWHGYRVLATPSTCIQFKPNCDTFTLDAVP
QGWRELNLMPDGSIETIVKRLDCVKFLPNFAAQGY
>A0A5E7FR83|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTVNPDGSALLVQLSDSHLFAEGDGTLLGMNTRDSLQRVIELARAQQPRIDLVLAT
GDLSQDGTLESYQQFRDMTAPIGAPTRWIPGNHDEPQIMAHAAVHSDFLEPVVDIGHWRV
TLLDSAVPGSVPGYLQDSQLQLLAQALSEAPNLHHLVCFHHHPVSIGCAWMEPIGLRNPD
ALFAVLDRFPHVRAVLWGHVHQEIDRERDGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERVQDFEFTVDYGSNGY
>A0A5E6UX53|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADSALLVQLSDSHLFAEAQGTLLGMNTRDSLQRVIELVRQQQPQIDLIIAS
GDISQDGTLESYQQFRDLTRQLDAPARWIPGNHDEPQLMAEAAVQSALLESVVDVGNWRV
TLLDSAVPGSVPGFLQDEQLQRLACSLSETPERHHLVCFHHHPVSIGCAWMEPIGLRNPD
ALFAVLDRFPQVRAVLWGHVHQQFDEMRNGVRLMASPSTCIQFEPGSEDFKVGMQAPGYR
WLRLLPDGQLETGVERVTGFEFEVDYGSNGY
>A0A5E7SVU4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEADGALLGMNTRDSLQKVIELVRAQQPRINLILAT
GDLSQDGTLESYQQFRDMTRQLDAPARWIPGNHDEPRIMAKAAVQSALLEPVVDIGNWRV
TLLDSAVPGSVPGYLEDEQLQLLARALSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQVRAVLWGHVHQEIDQIRNGVRLIASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGRLETGVERVIGFDFTVDYGSNGY
>G9KFQ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mustela putorius furo|TrEMBL
AQHSQRRESFLYRSDSDYELSPKAMSRNSSAASDLHGEDMIVTPFAQVLASLRTVRSNVA
ALAHLQGRGTVKQASVENPPTGSQPPPPT
>A0A5E7IRZ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MRNNYLTSRVTINTFLEGRGNQVVRVAAISDLHFSKHSKGCFINSWRELNFLADIFLLCG
DLTESGQVYEAEILANELKCVNIPVIAILGNHDFHSGYANELSAFLQAQGVVVLDGGNFI
YKVKDISIGIGGAKGFCGGFLGARAHIVGEPEMKSFAKLGTVEADKLTASLQSLSTDIRI
AIMHYAPIIDTLRGERAELFPFLGDFRLEEPLNRYQPTLAFHGHAHFGSLYGSTSAGVPV
YNVAYPLVRTAFRLFYIENSQKLS
>S7HVY5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio fluvialis PG41|TrEMBL
MSVNTADSFLAVVEAIRAQQLEFDAILATGDISQDHTAESYHRFTQGILPLEKICFWLPG
NHDYKPNMSSVLPSKQIHAPEHVLLGEHWQMILLDSQVVGVPHGRLSDQQLTLLEEKLSA
HPERFTLVLLHHHPLLVGSAWLDQHTLKDSEAFWTIVERHQNVKAVLCGHVHQDMDRLHH
GVRVMATPSTCVQFKPNSDDFALDKCSPGWRELELHADGRVTTAVKRLAKGLFQPDFNSN
GY
>A0A5V8XWN5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Kalamu|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2N0XTG9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. vnigr-6D03|TrEMBL
MKLSLDSNRDIRLLQITDTHLFEPEDGCLLSVNTQDSFHAVVNTVISRKLEFEAILATGD
ISQDHTAASYQKFEEGIAPLKKPCFWLPGNHDFKPGMHSIFPSTQIKTTSHVVLNNKWQI
ILLDSQVEGVPHGRLSQEQLDLLESKLTEFPDHRTIVLLHHHPVLVGSHWLDQHTLKDAD
DFWSVLSHHQNVEAVLCGHVHQDFDVMYQGVRVVATPSTCVQFKPNSDDFALDNESPGWR
MLTLTREGELKLEVGRLSDGEFLPDFSAGGY
>A0A385Z6X2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas cavernae|TrEMBL
MPSSPVSAADSSVLLVQLSDSHLFAETAGRLLGMDTQDSLQQVIARVLEEQPRIDLVLAT
GDLSQDASAESYTRFRQLTAVIPAPARWLAGNHDDMPVMEDVCAGSDLLEPIVDLGAWRI
VLLDTSVPGAVFGHLDAQQLELLEEALSSAPERHHLICFHHHPLDIGCAWMEPIGLRNAE
ALFAVLDRHPQVRALLWGHVHQEFDRQRNGVRLLASPSTCVQFAPGSEDFLVGGEAPGYR
WLRLHADGRLETGVSRVTGIDFEVDYSVKGY
>A0A8H9TUS2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter farmeri|TrEMBL
MESLLNLSLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHADRQEYDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKCVMVGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLSEAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDSIG
PGWRTLELFADGTLKTDVCRLQGTEFRPDTASEGY
>A0A674JM61|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Terrapene carolina triunguis|TrEMBL
MKEQHSCVGTGHLSMAGYGRMDPLELAVSPVKRLRTEYSFPYLFAEEAYQKLASETLEEL
DWCLDQLETLQTRHSVSEMASNKVGPIGLPCPLFFLLTCYQSWKSSG
>A0A3B4CVV2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pygocentrus nattereri|TrEMBL
LSRTTPPCSKKSLSLSLPVPREGQATLKPPQHLWRQPRTPIRIKHRGYSDTDRHPHRPME
RADAVDTSDRPGLKKSRMSWPSSFHGTSSAGIKNGPSPGRSPMDSQASPGLVLHPSFPQS
GRRESFLYRSDSDYDMSPKTMSRNSSVNSEGHAEDLIVTPFAQVLASLRTVRSNFTILAN
VTTPTNKSVSLSPLPNPNWY
>A0A5C4Q0P4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurellaceae bacterium Phil31|TrEMBL
MRTTFLHHSDKLPVRFIQVTDPHLFADKKADLLGINTFDSFSAVLSEIQQTPFTFEFVLA
TGDLTQDNNPEGYRYFCEEISQLQKPVFWIPGNHDYQPHMVETLNRYPEFISPLKHIIVN
DNWQILMLDSQVLNVPHGYLNQYQLDWLIAKIEQYPDLYTLVVLHHHIAPTRSAWLDQHN
LRNTSEFLSCLQQHHHIKAIISGHIHQEMDTQWNNYRILTTPSTCIQFKSDSYHFNLDIL
PPGWREFELYPDGSLITQVKRLKQNLFIPDFNISGY
>A0A4Y5YIX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella polaris|TrEMBL
MLKEAVHYSIAENEPVRLVQVTDPHLFADPEGQLLGVNTAQSLQAVLNTFIATQYPANIL
LATGDISQDYSPESYQHFVEKIEMLNLPCHYLPGNHDDPRLMSLRMQGEQIFGQQRVIIG
NWLILMLDSTVRGKPGGYMGEQQFALIDAAIKDEPNKHVLLVMHHNPILMQCAWLDQHCM
MNGEDFLQRTSRYPQVKGVLWGHVHQQVDNVHFGAHGPIPLMATPSTCIQFKPASSYFAL
DNLQPGYRLLELACDGSIRTNVYRVPGNRFAPDNEASGY
>A0A855S890|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium angustum|TrEMBL
MQTYSLPQTNPDSVVLLQITDTHLFANESGALLGVATQQSFHAVLNAVDASTRKFDAIVA
TGDISQDHTPDSYQRFAEGIARWEQPCFWLPGNHDYQPTMASILPSEQIKDCEQILVGEH
WQVVLLDSQVAGVPHGELSHHQLALLDHALSLYPERHALVLLHHHPLPAGSAWLDQHQLH
NSDALWQVIDKHPQVKAILCGHIHQELDRIHRGVRVLATPSTCIQFLPDSDDFALDQVTP
GWRYLELTATGDIITQIERLEGDVFQPTFDSAGY
>A0A8H9VJ30|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQEAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPARHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLVKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLAGAQFRPDTASEGY
>A0A0E1SR52|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae PittII|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNEFDVILA
TGDLVQDSSDEGYTRFVEIMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAEFLPNMQEEGY
>A0A1Q5VAR2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia fonticola|TrEMBL
MESLFRLPVASGAKVRILQITDTHLFAGKNETLLGINTYASYHAVLDAVIAQQRECDLIV
ATGDLAQDHSQAAYRHFADGITRLPAPCVWLPGNHDFQPAMVDALAAAGISPSKQVLLGD
NWQVLLLDSQVFGVPHGELSEYQLEWMERCLEAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHTLAAVLWRYPKVNTLLCGHIHQELDLGWHGRRLLATPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A6M1ZKA9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Anoxychlamydiales bacterium|TrEMBL
MITIAHLSDLHFSNISIFPLSLKRFIGTTNLLITRKRSYIDMHLSKLPNLLKSLDVNNIF
ITGDLSSTSLKKEFEKAKKFIDSFDENIKFFIVPGNHDTYTKQADKCSYFQNIIKSKNIL
NTKKQKIHLSDLSEKWVYIGLDTTLVTPIFSATGLFSTEIEKDLIDILEKIPKDKNIIIS
NHFPIFHKAAKRKLLKRREALLNVIKRYPNIKLYLHGHTHKRSITKEDNMPYMICSGCSA
HKKNASFNILKIEDDKCFMQSYILQDSNWKKDRVEELNFS
>A0A5H7CRR5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Tudu|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A4R2T3S5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cricetibacter osteomyelitidis|TrEMBL
MLNTLIYDARKNEAKDLVVRFIQITDPHLFKNEDTELLGINTQASFEQVLKEVKQSDFDY
DFVLATGDLVQDSSKEAYQRFAEQIKTLGKNVHWIPGNHDFQPTMFEVLNQADNRISAVK
HLLAGKRWQIIMLDSQVYGVPHGQLISYQLDWLLSKLKDHPQRYSLIVLHHHIVSTNSEW
LDQHNLRNAQELSEVLAPFNNVKGILYGHIHQQVDTQWNGYQVMATPSTCIQFKPDSHHF
ALDTLQPGWREIELYENGEIKTCVKRIRQKAFLPDFKEEGY
>A0A644Y3K3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKKIVICCFILLCFTATKAQKLNFNKNGLFKIAQFTDVHYVHGNSKSDTALLNIQRVLDT
EKPDMVIFTGDAVTGRPVKTAWDALTKLVIDRKIPFAVALGNHDDESGTTRFELEKIITS
YPYNCNYPTSGQLNGVMNNVIPVYGSEKDMQVKSLIYCFDSGTYSTISDVPGYGWITSDV
IDWYKKQSFHFTRQNNFQPLPALAYFHIPLPEYRLAFNDESNKRVGVRKENECPPDLNSG
MFIAMKEMQDVMGIFAGHDHVNNYMVNYYGIALTYGQFSGWRTTYVPEINGARIVQLTEG
KREFDTWIRFLDGTVKYKATFPADLTNN
>A0A644UYS4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MEVVIKQRIHLLLISVLLSSCIGDTDLTGFIRSTDRIEDRFKASMEWNTSNPFKTITVAS
EAYNLLLASDVHVGETENYQKFLQQGIQNDIEALIFVGDFVTGKEKDYEKFNDLLPDYET
KPRFLLTGNHELYFDGWKHFQRLYGTSIYYFTVQTPSVRDLYICLDSGSGTLGKSQLAWL
KNLLQQGRNLYNQCVIFTHVNFFRDRHTLSTNPLVNELLVLLDLFEKYRVNLVVMGHDHV
RAENQLGNTTYLTLDGLEDEIPNASYLLLKKEISGITYQFIGVK
>A0A644SNH6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKTNFIILLAVFFIIEIYVYQAIRNITTNNYIRIGYWVFTLLAYGIILYWILTFNRASRD
HQQIQLMVSAMMIFVLPKLLSVIFLLIGDFTRFVEFGFKYFTTKENYFPERRKFISTTAL
AAAGIFSALAIDGIIFGKYRHTVRKVKLRFKNLPESFKGYKIVQISDVHSGSFFNPQKLQ
KAIDLINEQDADVVLFTGDMVNNYADEFKPFIPLFKSIKAKDGKFSILGNHDYGDYGAWN
SREEKAQNIPTLKNYQAEAGFKMLRNENIALEKNGEKIYLLGVENWGIKPFPQYGDLDKA
LKGVPEDAIKVLMSHDPTHFDEVVKKHKTNVHLTLSGHTHGMQFGLDLKNIKWSPVKFKY
KKWADLYKSEGKYLYVNRGFGVIAYPGRVGINPEITVIELV
>A0A481QJZ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia hibernica|TrEMBL
MESLFKLPMASGAKVRILQITDTHLFAGEHETLLGVNTSRSYRAVLDAILAEQHPFDLIV
ATGDLAQDHSVAAYQNFTKGISRLPAPCVWLPGNHDFQPVMVDVLANAGIAPSKHVLIGD
NWQILLLDSQVFGVPYGELSDYQLEWMERCLVAHPERYTLVLLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGRLETEVRRLASDEFCPDMDSDGY
>A0A8C5X3F5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Malurus cyaneus samueli|TrEMBL
CDKTNYVLEIFLSMAQKFFSSFCSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRR
ESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQD
RAPSKRSLLEATVALF
>A0A8C5TIY7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Malurus cyaneus samueli|TrEMBL
MAQKFFSSFCSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDL
SPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSNVCHQTRMK
H
>E6WD50|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. (strain At-9b)|TrEMBL
MDSLLTLSAASGADIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIEAQQREYDLII
ATGDLAQDHSVEAYQHFVSGIARLPKPCVWLPGNHDFQPAMVNTLADAGIAADKHVLLGE
HWQLVLLDSQVFGVPHGMLSEYQLEWLEKTLAKFPDRHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLQNFPRARNLVCGHIHQELDLDWHGRRVLATPSTCVQFKPHCTNFTIDTVA
PGWRWFTLKPDGTLHTEVNRLQSDAFRPDLDSEGY
>A0A5Y7A8W4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Choleraesuis str. CFSAN000515|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A4W4GX88|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Electrophorus electricus|TrEMBL
MLNRELTHLSEMSRSGNQVSEFISNTFLDKQNEVEIPPPTPKAREKKKRQQLMTQISGVK
KVSHGPSLNSGITRFGIKTDKEDLLSKELEDLNKWGLNIFTVSEYSNNRPLTCIMYAIFQ
ERDLLKTFKIPADTFVTYMMTLEDHYHSDVAYHNSLHAADVAQSTHILLSTPALDAVFTD
LEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEENCD
IFQNLTKKQRQSLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRI
QVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFHQGDRERERGMEISPMCDKHTASVEK
SQVSPAWLELSGNNCCRHFGDE
>A0A7X1WUN5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas helleri|TrEMBL
MPNASTPTTEHSVLLVQLTDSHLFADADGSLLGLNTAQSLQQVVDKARAEQGQVDLLLAT
GDLAQDGSVAAYQRFRQVSEPLCANARWLPGNHDRLAQMREATVQTRLLDPVVDIGNWRI
ILLNSQVPGATPGYLEEEQLQLLARAVSEAPQRHHLVCLHHHPVPVGSEWIEPIGLRNAK
EFWAVLDRFPQVRAVLWGHIHQPFDQIRNNVRLLATPSTCVQFTPGSTDFDVSDEAPGYR
WLRLHPDGALDTGVSRLDNFVFTPDYSANNY
>A0A4Q5KXY5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aliivibrio finisterrensis|TrEMBL
MLSETLLNNENGPIRLLQITDTHLFAPEDGALLGVPTLKSFQTVVEQVQQRTPNFDAIIA
TGDISQDHTVSSYQHFVDGIKPLVKPCYWLPGNHDYKPSMGGVLPSSQIQACEHLFIGQH
WQLIILDSQVVGVPHGALSKEQLALLDSVLSQNPDRHSLVLLHHHPLPAGSAWLDQHQLK
DNDEFWSVVGQHDNVSGIVCGHIHQELDRIVNGARLLATPSTCVQFLPDSDDFALDSQAP
GWRTLDLLPDGRIETQVHRLENCDFSADSNAGGY
>A0A5M9ICH8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas panacis|TrEMBL
MPTKIIHISDTHFGDPSPTFDRGSIKRALIKQINEIDEEKILVISGDITYKASQQGYRDA
ERFFSEVIDSCKISRSNIVACPGNHDIASDGEPFKEFDRFIYTLRRDNAIEFANNSSVLL
TIQDTCFLLVNSASHLDHRYGNIPDSTFSLLDKEISTLKHCSRRVAITHHHLIGQELNDT
STTRNAYRFLYNLDQASFNYVLHGHQHSKLDLVVGQNKIRILSARSMSYHGRGYSNGITI
IDLESGTATPVIWTPDEVPGLLTTGVIK
>A0A346B786|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia caffeinilytica|TrEMBL
MSAERESKSKAKAKESAAKAEGKRKPASKAAASGKQATALAGSPSQPAGASTATALRPRM
LDKPVFAQPQPTADPTVFRVPHPSDDAAYKEIDKLNAEHKLFPLPFPAPRGGVEPQLTLA
EVMGGNASTIDRITAGGQLVFHALGDCGNTKGPATQNEVADKLTADFNEANASEVPQFAL
LLGDVVYSFGESQYYYDQFYEPYRDYPAPILACAGNHDGMVSPEAHAASLAAFLRNFCAE
TFAVTPEAGGLSRTAQIQPGVFFTFEAPFVRVLVIYSNTLEDPGVISDPNIGRTQLDFLD
AALKRVKAEQFSGALLIADHHPPYSAGGHGSSVDMLAQIDKVCEANGVWPHAFLSGHAHN
YQRFTRTRNADGTQIPYLVCGNGGHGLIKLAARGAPALRAPQIMQAASATTDQVVLENYD
DTNYGYLRIVVTATQLRIEYHSASDGLNTKAPNDYVTVDLAERKVAHFVASDLGHPMAAR
AVRALVR
>A0A151KT52|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cidicii|TrEMBL
MQHTTSDTSSIKLLQITDTHLFATDEGSLLSVKTLQSFQAVVEQVIQRQVAFDYVLATGD
ISQDHSAHSYQHFAKGIAPLQKPCFWLPGNHDYKPNMSSVLPSSQITAPEYVALGEHWQM
VLLDSQVVGVPHGRLSDSQLALLEEKLASNPSKHTLILLHHHPLLVGSAWLDQHTLKDAE
VFWEIVYRYPNVKGIVCGHVHQDMNRMHHGIRVMATPSTCVQFKPNSDDFALDNVSPGWR
ELQLHADGEITTQVQRLSAGSFLPDFTSSGY
>A0A8F6CU86|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylococcus capsulatus|TrEMBL
MPDSGTLCLLQLTDSHILPDAESRFYGSDSAASLGAVIDHANRRRFDLVLFTGDLAQEPV
PQSYRRLAGICAALPAPCHWLPGNHDEPALARHVLESTPLLHQPVIRRGRWLIVCLDSTV
PGSAGGSLSTGQFDLLERTLSRHPSLHTLVALHHHPVPSGSAWMDTMILDNAGEFFAVLR
RHPQVKAVVHGHTHQVADVEIEGTRVLGTPSTCIQFRPASQTFALDAERPGYRWLELGPD
GSVATGICRVAVPPASDTA
>A0A418ZAK5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Mbandaka|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A5D3I8C0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moorella thermoacetica|TrEMBL
MFRVLHLADLHLGYRPDLPAPVREEVYRARNRVLQAAVDLALDPRQGISLVLIAGDLFDN
HRPEASLVEETIRQLTRLEAAGIQVITVPGNHDEITYNDAVYRREAGRWPGLLVTDPMPA
KVATLKVKGDTCHLMAMAYTGGVTRVDGPLKAFPPAEGEGVNLAVFHGSLDWDGGERSLP
LDGEALAAAGYDYIALGHIHRGGQRRLGRGLAVYAGMVAGKGFADPGTGSWTIVTLGDGP
ARVEQVPARVTPWRLVDLDVTAFQEPEELETAIREALDPGALMQVRLTGSLAFDLDLEGL
QARLGHPCPYLELVNETAGWTPEILESIAAEPTIRGLFVRRLQEKLAGSAGPGEAEVIRR
AIFRGLLALKGGSR
>A0A0A5UEG9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Morganella morganii|TrEMBL
METPLHLPVADGAAVRILQITDTHLFAGETDTLLGINTLHSYHAVLDAIVKQQLPADLIV
ATGDLVQDQSTRAYQRFTDGIARLPAPCVWLPGNHDYQPSMAQELAAAGISPSKQVLLGD
QWQILLLDSQVQSVPHGELSDDQLIWLDNCLAQQPDRHTVVMLHHHPLASGCTWLDQHSL
RNSHMLAEVLTRYQNIEGILCGHIHQDLDVMWNGIRMLATPSTCVQFKPHCTNFTLDTAA
PGWRYLELTTGDNPSLTTQLFRLDTDEFSPDLGSDGY
>A0A737VTL6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae serovar 58:d:z6|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A547E7Z9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mannheimia haemolytica|TrEMBL
MDAKRMHEYIKLPVTGVIKLLQITDPHLFSNPEETLLNVKTVKSFSAVIEQINKQAKQYF
DLVLATGDLIQDNNIAGYHYFAQITNSLNSPIVWLEGNHDVQPSMSEILAQYKHILPHKQ
ILLGEQWQLLMLNTQVVGMPYGELSYSQLKWLEEKLAQYPQRFTLVALHHNILPTNSAWL
DQHSLKNSNELSEIFAKFKNVKAIVHGHIHQQVDDIWHGIPIYATPSTCIQFKPNCDQFT
LDLQPQGWREIELHENGTIETVVKRLNSNDFLPNVNAIGY
>A0A1C0P3Y5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter freundii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRARYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A0F1PGD1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter hormaechei|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEKRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGD
QWQILLLDSQVFGVPHGELSDYQLDWLETKLAAEPNRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDGVLAKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLAGAQFRPDTASEGY
>A0A7V8PDV5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium versatile|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKARQDAFDLIV
ATGDLAQDHTLQAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSAVLDRYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A1Z1SSI1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteus mirabilis|TrEMBL
MESQLELSVDQQHTVRILQITDTHLFANVDDTLLGINTYRSYHAVLDAIKQQGLSIDLIV
ATGDLVQDQSFAAYQHFADGIARLPSPCVWLPGNHDYQPAMIDALNQAGILSAKQVLIGE
HWQLLLLDSQIQGVPHGELSDCQLDWLTRCLESHKERDTVILLHHHPMPSGCTWLDQHSL
RNSHQLAERVKDHPQIKMMLCGHIHQEMDEMWNGIRLLATPSTCIQFRPHCTNFSLDTVS
PGWRYLELSLSAQGKRNIDTQVHRLAGKDFCPDLDADGY
>A0A2B7LWJ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia marmotae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILMLDSQVFGVPHGELSEFQLDWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A853STX7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Janthinobacterium sp. HH102|TrEMBL
MRTIVHLSDLHFGRVDGDLLAPLRALVERLEPDVVVVSGDLTQRARSAQFQAARHFLDSL
PGPQIVVPGNHDVPLYNVFSRFLTPLVKYRRHVTDDLSPEYVDEEIAVLGINTARSLTFK
DGRISHEQIDFLRERLGRLPPGLTRIIVTHHPFDLPEHFDEDDLVDRAPQALQMFSECGV
DLLLAGHLHASVAGNTAERYKIAGYAALMVQAGTATSTRGRGESNSFNVLRVENSCIRVE
RYSWNEDSAEFEKVSTEAFERQGGVWASLRPL
>A0A6P8LH81|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bombus impatiens|TrEMBL
MQELHPFYYHALFKNHENQIHLVHVFHGKTEYDVLRRRSSFEDVAVDDDENADCSALKGP
QNIEAHPLTNSVPSLIKILLVFPKDDQQMDVLATTSRRLGWSVSVAKDAEKAVEFFQNRG
HELVIIDHRGQRAAEADTICRYGELFFKNQSNSSDVRLYILINTIYFRAIRSSPAYHNSI
IIALVKKSFLMHGEKDKIVTLDLLETGFSRALMECSHERLLINELVGIYASALLPRTQLA
AANALYVALDRCRDMVHVTNDKHIVQFVNKISEKLLGYKTSEILGKSIADIVVYDNFVLM
EQHISKGREFEGNMNCKRKNNQMITISCRVIPFSINLKKPTHYIYIYDTTYLSENIGSLS
PTPSQSVYSRGNMIVSQRRTSDMKSSEGRRRSSAHKLHSLQLDAPITKVISLLSNAITES
TTPDTAAQIEKAIDILKTTELYVPSLREDTDPVTTDLVGALLASPRKAWESRRSSVESTR
VSTSKAFTTTTASRMQIKSFRGPQEIAEILERCLEWNFDIFKLEILTEKRPLLFLGTTIM
NMYRVPARLGCEEKVVQNWLTVIEMNYQSRNSYHNSTHAADVLQATARFMQSERLQQILE
PLDEVATLVAAAAHDVDHPGRSSQFLCNSDNKLAILYNDLSVLESHHAALTFKLSLSDDN
VNIFKNLERDTYKQLRQTVIDMILATEMTKHFEHLAKFMNICSARMMDSPQLDDYTDTVD
MSVVLQPENVVLVKRMMIKCADVSNPTRPLKCCVEWARRIAEEYFNQTDEEKRMQLPVLM
PMFDRATCSIPKAQIGFVDFIINDMVEAWDAFIDMPEMVGYMRQNYEKWKEYNDRGISTL
PDIEKIQELPELRIYQLPS
>A0A1S0ZQ79|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLVLQANGVLETEVHRLQDTRFRPDTASEGY
>A0A3I8FMD8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGD
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A6P8KVI1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bombus impatiens|TrEMBL
MGCKTSMLECIEDTGEAEKRKHSDMVNQGSLLGKTEYDVLRRRSSFEDVAVDDDENADCS
ALKGPQNIEAHPLTNSVPSLIKILLVFPKDDQQMDVLATTSRRLGWSVSVAKDAEKAVEF
FQNRGHELVIIDHRGQRAAEADTICRYGELFFKNQSNSSDVRLYILINTIYFRAIRSSPA
YHNSIIIALVKKSFLMHGEKDKIVTLDLLETGFSRALMECSHERLLINELVGIYASALLP
RTQLAAANALYVALDRCRDMVHVTNDKHIVQFVNKISEKLLGYKTSEILGKSIADIVVYD
NFVLMEQHISKGREFEGNMNCKRKNNQMITISCRVIPFSINLKKPTHYIYIYDTTYLSEN
IGSLSPTPSQSVYSRGNMIVSQRRTSDMKSSEGRRRSSAHKLHSLQLDAPITKVISLLSN
AITESTTPDTAAQIEKAIDILKTTELYVPSLREDTDPVTTDLVGALLASPRKAWESRRSS
VESTRVSTSKAFTTTTASRMQIKSFRGPQEIAEILERCLEWNFDIFKLEILTEKRPLLFL
GTTIMNMYRVPARLGCEEKVVQNWLTVIEMNYQSRNSYHNSTHAADVLQATARFMQSERL
QQILEPLDEVATLVAAAAHDVDHPGRSSQFLCNSDNKLAILYNDLSVLESHHAALTFKLS
LSDDNVNIFKNLERDTYKQLRQTVIDMILATEMTKHFEHLAKFMNICSARMMDSPQLDDY
TDTVDMSVVLQPENVVLVKRMMIKCADVSNPTRPLKCCVEWARRIAEEYFNQTDEEKRMQ
LPVLMPMFDRATCSIPKAQIGFVDFIINDMVEAWDAFIDMPEMVGYMRQNYEKWKEYNDR
GISTLPDIEKIQELPELRIYQLPS
>A0A6J5JY36|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia phenoliruptrix|TrEMBL
MSSHSFDPSRRGALKCLAFGGAGTLFVLAGGVLTPMQLALAADGKPAATAGVPLFLQISD
THIGFNKEANPDVAGTLKQTIEFVNAMPVKPALAIHTGDITHLSKAAEFDLAAQLLSGLP
VTELHTVPGEHDVTDGPGTEYFSRFGQASDNKGYYSFDHDGVHFVGLVNVMHFKPNGLGS
LGDEQLKWLENDLKARSSSTPIVVFAHMPMWTIYEPWGWGTGDAGEAMSYLKRFGSVTVL
NGHIHQIVSKVEGNITFHTARSTAYPQPAAGQGPGPGPMTVASAQLPKMLGVTSVTIARH
PLGATLADATLVS
>V8NT38|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ophiophagus hannah|TrEMBL
MDPLELAVSPVKRLRTEYSFPYLFAEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKLSLPNHAIVLM
>Q2BYT4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium sp. SKA34|TrEMBL
MQTYSLPQTNPDSVVLLQITDTHLFANESGALLGVATQQSFHAVLNAVDASTRKFDAIVA
TGDISQDHTPDSYQRFAEGIARWEQPCFWLPGNHDYQPTMASILPSEQIKDCEQILVGDH
WQVVLLDSQVAGVPHGELSHHQLALLDHALSLYPERHALVLLHHHPLPAGSAWLDQHQLH
NSDAFWQVIDKHTQVKAILCGHIHQELDRIHRDVRVLATPSTCIQFLPDSDDFALDQVTP
GWRYLELTATGDIITQVERLEGDVFQPTFDSAGY
>A0A671KJQ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sinocyclocheilus anshuiensis|TrEMBL
MLNRELTHLSEMSRSGNQVSEFISNTFLDKQNDVEIPSPTLKAREKKKKQQLMTQISGVK
KVSHGPSLNFGIARFGVKTDKEDLLSKELEDLNKWGLNIFTVSEYSNNRPLTCIMYAIFQ
ERDLLKTFKIPADTFVTYMMTLEDHYHQDVAYHNSLHAADVAQSTHILLSTPALDAVFTD
LEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCD
IFQNLTKKQRQSLRRMVINMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYIDRI
QVLRNMVHCADLSNPTKSLELYRQWTDRIMDEFFHQGDRERERGMEISPMCDKHTASVEK
SQVSYCLRCNGFLFFCTNTNFL
>A0A2S4TZD4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sp. ASNIH8|TrEMBL
METELPQAPDGSVRLLQITDTHLFASAEGRLLAVPTAQSLAAVLERVQANEHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGDHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHHGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRVASQVWRLPLGQFVPDPNATGY
>A0A8C0AYA8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Buteo japonicus|TrEMBL
YFQNSYVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSR
NSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATI
TGKKN
>A0A427X793|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. FDAARGOS_559|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIQQILKQHPEADAIIHT
GDLAQAPTPITYKRYINFMQTLGLPFFQTLGNHDNVDHFPLHNENHQQPVVVGLGNWRVI
MLNSAVKGKVDGHLSSEQLENLANLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFQNVKALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLNNDGSFETKVFRLENFKTRINTDISGY
>A0A2H5Y712|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Thermoflexus japonica|TrEMBL
MPRRRFRPGTEASPFHQFMVALNRLERLPWAFLGLWALALGIIIGLAWWDASGSPGVGVS
AGGTFLAFAGGDALMLILLPRLGYSFGPPKPPFVAFTLFRLFLSLGTLPLRPLSWAIGLA
LIGHLAFTGNLLNALYREPFQLTLTELVVASPRLRGMPPLRILHLTDLHLERLTRREQQV
LQWIDELDPDLIVFTGDLLNLSYVHDPHAQAQCSRFLEALHAPLGVYLVTGTPLVDPPEV
VRRILFGFTHITWLDNQVARFGQLGHQGPQICLLGLTCTHDPEHDGERLRALMRQIPAHA
LTILLYHSPDLFPEASALGIDLYLCGHTHGGQIRLPLIGALVTASIYGKRYEMGLYRHGS
TTMYVSRGLGMEGLGMPRMRLMCPPEIVLIHLQGDEPEETESRSASPI
>D0X0F5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio alginolyticus 40B|TrEMBL
MQSSSDSIKLLQITDTHLFAADEGSLLSVKTVDSFNAVVADVLRRNVAFDYILATGDISQ
DHSAESYQRFANGIEPLEKDCFWLPGNHDYKPNMGSVLPSPQIKAAEHVLLGEHWQLILL
DSQVVGVPHGRLSDQQLTLLEEKLAEHPERHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVERFDNVKGILCGHVHQDMNVLHKGIRVMATPSTCVQFKPNSDDFALDTTSPGWRELQ
LHACGDITTQVGRLPDGQFQPDFSSNGY
>J3DAP0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. GM01|TrEMBL
MDSLLTLPAVDGSGIRILQITDTHLFAGKHQSLLGVNTWSSFAAVLDAIEAQQQHYDLII
ATGDLAQDHTVEAYQHFVAGISRLPKPCVWLPGNHDFQPAMVDTLADAGIKSDKHVLLGD
HWQLVLLDSQVFGVPHGMLSEYQLEWLDTALRKYPERHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLQHFPRARNLVCGHIHQELDLDWHGRRVMASPSTCVQFKPHCTNFTIDTLA
PGWRWFTLQPDGTLETEVNRLQSDMFRPDLDSEGY
>A0A061I718|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cricetulus griseus|TrEMBL
MAQSLDAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSR
NSSVASEAHAEDLIVTPFAQVLASLRSVRNNFSLLTNVPIPSNKWSPLGGPPAVCKATLS
EETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQV
SEYISTTFLDKQNEMEIPSPTPRHRAFQQPPPPVVQQSQPMSQITGLKKLVHTGSMNASI
PRFGVKTDQEELLAQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGME
ISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRDWYHSAIRQS
PSPPLEEEPGHLGHPTLPGKFQFELTLEEEEEEDSLEALGLSTAEEISLASDDITAQATE
QSKVKDKDPNSEVVEREKSLRQGADPACATPKESVETVGCSFSPGTPILPDLRTLCPPEE
VPGLLGLPSMAAEVEAPRDHLAASRAYACSGTTGDSSAIVSASGTLGSGGDPA
>A0A433ZXR2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Morganella morganii|TrEMBL
MEIPLHLPVADGAAVRILQITDTHLFTGETDTLLGINTLNSYHAVLDAIAKQQLPADLIV
ATGDLVQDQSTGAYQRFTDGIARLPAPCVWLPGNHDYQPSMAKELAAAGISASKQVLLGE
QWQILLLDSQVQGVPHGELSDDQLIWLDNCLAQQPDRHTVVMLHHHPLASGCNWLDQHSL
RNSHMLAEVLTRYQNIDAILCGHIHQDMDVMWNGIRMLATPSTCVQFKPHCTNFTLDTAA
PGWRYLELTTGEQPSLSTQLFRLETDEFSPDLGSDGY
>A0A2R4TR68|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas hydrophila subsp. hydrophila|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRIASQVWRLPVGQFVPDPNATGY
>A0A1W4ULF6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila ficusphila|TrEMBL
MRNCLPKFSKVFRRKSSAKSSSTGGLGRENPSNEPDSDTEPYAIAAIADRGGDNRNERPL
PDDDSSRRRLISVAHLNSDSDLPANGKGVPFSQHRSTDEGSCPEMKVETISTTTATTADS
VPLASGQAAISQPFAGRNSSKTPEEMELEYEATVEAESRDIMTPLRRNTRPLSVSFGAGR
TALQPEIVEAIRSLDVPALLLNNLNLDGGRGAEVETRSQSHSQSQSGEMSPGHELEDSVV
LRRKVNCLERKAHSLYERRLPKVPKLHLLVAGKKSKADEEREAEAEELRTFQRNLMDLKY
PTVLPPNPPLKALLVFHKSDSICEAVTAACQRHQLDVTLVKSKEEALDTLQKSYATAQCY
HLIIIDARSTKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCV
AETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRAT
ERLLNMRLDEIISKQLEDIFVSDLSTISEQCKSIKEFDGILTVRRKSQEGIPMHVRVVPV
ACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTS
LAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDP
IATDLIGALLTVTKGPSVYSSRRSSNDSIIRTGSSTRTASIVPAKMKSNPIIMELLDESL
SWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYH
NSTHAADVMQATGAFITQLTNKDMMMMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDA
LAVLYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHF
EHLAKFVSVFGGEEPRDHNSQTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEE
YFMQTDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMIHAWESFIDMPQLITYMQ
INYSQWKKYDEQGVNTLAEIMAKQPPVGKMANSK
>A0A662DZ70|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinomycetia bacterium|TrEMBL
MSHKPIADPPPAPTLPPGAFRIVQITDSHLYASADGLLAGINTLDSFHAVLDLIRTPALS
ADMILATGDLVHDASPPGYQRVKKAFSGFGIPVYCLPGNHDLPQVMSECLNQGTITSPKW
ITHSGWRIAMLDSTIPGEEGGHLSETELRQLRSGLEQHPDHHALICLHHHPVPIDSAWMD
QMALDNPDPFFSLLEQFPNVRGILWGHIHQAYDSQYRGMRLMGSPSTCIQFAPRIDHFGI
DDEPPGLRWLELYPDGGIRSGIKRLQQMPLGLDLSSVGY
>A0A7Z2L992|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas asturiensis|TrEMBL
MPSAAPSSSVLLVQLSDSHLFAEADGTLLGMNTRDSLEKVVERVLAEQPQVDAVIASGDI
SQDGSVASYEAFQRISEQIKASARWFAGNHDELPQMEHVAQAAGFLDPVLDVGAWRVTLL
DSSVPGSVPGFLAESQLQLLERSLSEAPDRHHLVCLHHHPVPIGCEWMAPIGLRNADAFF
GVVDRFPHVRAVLWGHVHQEFDQVRQGVRLLASPSTCIQFAPGSEDFRLDTLAPGYRWLR
LHDDGQLETGVSRVVGMVFEADYGGTGY
>A0A2Y9TX54|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Limnobaculum parvum|TrEMBL
MESLFQLPLARGSKVRVLQITDTHLFAGADETLLGVNTLKSYQAVLRAIAERGHDYDLIV
ATGDLAQDRSFAAYERFTTGIATLPAPCVWLPGNHDFQPAMVDAMAAAQILPSKQVLLGE
DWYIILLDSQVLGVPHGELSEYQLHWLDRSLTQYSDRHALILLHHHPHSSGCTWLDQHSL
RNSHILAEVLDRHPQAKTLLCGHIHQDLDLDWHGRRVLASPSTCVQFKPHCTNFTIDDLA
PGWRYLDLYSDGSIETTVCRLEGDVFRPDMNSDGY
>A0A2U8FIS2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinobacillus porcitonsillarum|TrEMBL
MNVFYQLGKDEPVVRLLQITDPHLFSEPSTCLLGVNTHQSLQAVLAEIQKTNVDFHAILA
TGDLIQDHQVQGYHHFARMIEPFKKPVFWVEGNHDEQPQMSLCLGEYSYIQPEKQIFAGR
YWQILLLNSQVAEAPSGYLSRGQLAWLEKSLSENSDRFSLIVLHHNILPTHSAWLDQHSL
KNADKLAEILARFPKVKAILHGHIHQEVNAIWQNIQIFATPSTCIQFKPNCDEFTLDMLP
QGWREISLFEDGRIETKVKRLKSNDFLPNLEAKGY
>A0A8C7IR79|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oncorhynchus kisutch|TrEMBL
MLNRELTHLSEMSRSGNQVSEFISNTFLDKQNELEIPCPMAKTREWKKRPHHQTQLEGQG
TLTQISGVRKLSQSTGLQGSSISRFGVKTDQEELLSEDLENINKWGLNIFRVAEHSHNRP
LTCTMYTIFQERDLMNTFKIPTDTFVTFMMTLEAHYHSDVEYHNSLHAADVAQSTHILLS
TPALDAVFTDLEILAAVFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVG
FKLLQEENCDIFQNLTKKERQSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGV
LLLDNYTDKIQVMRNMVHCADLSNPTKSLDLYRQWTDRIMNEFSHQGDREREKGMEISPM
CDKHTASVEKSQVGY
>A0A7Y4EHJ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. RE86|TrEMBL
MKVTSITSDKDSIKLLQITDTHLYEPVDGSLLSVKTLDSFHAVVEAIVADGSSYDAILST
GDISQDHSAQSYQHFEQGIAPLEKPCYWLPGNHDFKPSMNSVLPSNQVQQVEHVLLGEHW
QMVLLDSQVVGVPHGLLSDDQLQLLDDKLSEHPERHTLVLLHHHPLLVGSRWLDQHTLKE
ADNFWQVVAKHSNVQAVVCGHVHQDMNVEYQGVQVMATPSTCVQFKPNSDDFALDTLSPG
WRELELHKDGLVTTDVKRLPAGSFQPDFNSAGY
>A0A6N2JUJ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudanabaena sp. UWO311|TrEMBL
MNYGSFVSIAQLTDIHLFEDIESSLVGIQTEASFQEVLTDIKRTLPQTDLLLLTGDLTQD
GSAASYNRLRRSLDKFGIHSYCLAGNHDDLLLMQSQLPSEYVHLSRSLDVGKWRILLLSS
VVVGAVHGYLADSELAWLEDNLYAYPDRPTLIAFHHPAVPLGSQWIDGICLENQDQFWEI
CDRHPQVEVVLNGHAHQDFDQIYETPHNSVRCLVTPSTCIQFQPQNHKFQIDSQPPGFRH
LRLYPNGVMETEVHRLKVGSFHPDLAASGY
>A0A4U1BQB3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ferrimonas aestuarii|TrEMBL
MSARTKVMLEGLDQETIRIAQLSDPHLLADKSADFLGQNPWDSFMAVLEMIASLNPHLLL
VTGDISQDHTLTAYQHFAASVTQLGVPVASLPGNHDALVRMQSGFAGSGIMMNEQIDLGH
WQLLQLDSTLPRVPAGALSEASLNWLDSTLGLSDKPTLVALHHHPIDTGCKWLDQHRLAN
GKELLKCVEQHNHVKGVVWGHVHQQGDYQLNQAQLMSVPSTSIQFKPQCDDFTLDTLQPG
FRLLELHRDDSISSQVYRLPGERFLPDMSVSGY
>A0A4Y8SRI7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. RIT623|TrEMBL
MPQPLSPPSPVHVVQLTDAHLFADPAGTLLGLNTRASLGHVVGQVRREQPRIDLLLCTGD
LSQDASVESYVAFGELTSTLGAPARWLPGNHDEARVMTEVAPELVQAVTDIGAWRIVMLD
SAVVGATFGLLADDQLLVLDQALNGAGERHCLVCCHHQPVDIGCAWIKPIGLRNADELLR
RLRSYPQVKALLWGHIHQEWDEVRDGIRFLATPSTCIQFAPRSEDFKVSEEQPGYRWLRL
HADGRLETGVERARDFVVKLDFDSPGY
>A0A261DYW3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sp. A35_P|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRIASQVWRLPVGQFVPDPDATGY
>A0A7Y4RWD0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylococcaceae bacterium|TrEMBL
MTQIPGRLSLLQITDMHILPRPEDTLLGINTNYYFNAVLAAAFAERPHYDLILLTGDLAQ
EPCPASYQQILNSLLPYQTHCVCLPGNHDDYSLMQQVLNTDQISCNKQVFIGNWQLICLN
SQIPGSPGGRLANEELIFLEQCLTDNPDVPTLIAFHHHCLETNSTWMDTMTITNSQAFFS
IIKNYSQIKAITTGHIHQVMDTTINTIRVFGTPSTCFQFKPKSRDFGLDTIGPGYRTLDL
YNDGRIESTVIRLQEPLKGLQLNSQGY
>A0A7W2X8W1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. RHBSTW-00901|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYNSLHEAGISPAKCVFAGD
QWQILLLDSQVFGVPHGELSEFQLDWLENKLAAEPSRHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLVKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLSGAKFRPDTASEGY
>A0A836FDN9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acromyrmex charruanus|TrEMBL
MGCKISIPKCMKDKVEQEKSISSETSSSSIVISDTTEPDRDEDSLYFAFDTFKSHNFITE
EDDQKVEQHKTDAFEIVAEKNEKTPFEDNTNDDYDENGDYLTVKGPQDFSNYLLTTNVPS
IVKILLVFSKDDQQMDILSNTARRLGWSVSIAKDAEKALELFQNRAHELVIIDHRAHHAA
DGDAICRTIRSSPVYHSSVIIALVKKSYFMVDEKGRIVALDLLKTGFDRALMECSHEGIL
INELVGIYTSSLLPKTQLAAAHALYLALDRCRDMVHVTNDKNIVQFLNKISEKLLGYNVE
EMMGRNLSEIVSYENFPLMEQQLNKGREFEGNMNCKRKNNQMIMINCRIIPFCITLKKPS
HYIYVYDTTYLSENSAPISPISSPLHPPLKTITTNARKSSDVRSGSISEDKGRRRSSLQK
LHTLQLEAPITKVITLLSNAVTDTTNPETAAQIDKAIDILKTTELYIPHLKEDRAMCCDP
VATDLVGALLSSPRTTWESRRSSSDSARLSAIKAITSPTNSRVQVKNFRGPQEIMEILDK
SLDWDFEIFKLEVLTEGRPLVFLGLTIMNLYGVPATIHCDERTLQNWLAIIEHNYNAENS
YHNSTHAADVLQATARFMQSKRLKEILEPLDEVAALVAAAAHDIDHPGRSSQFLCNANSR
LAILYNDLSVLESHHAALTFKLSLSDDSVNIFKNMERDAYKLLRQNVIDMILATEMTKHF
EHLAKFMNVCSARIGDGQETYSDSLDMTVVLQPDNVILIKRMMIKCADISNPTRPLKCCV
EWAKRIAEEYFNQTDEEKKLKMPVVMPMFDRLTCSIPKSQIGFVDYIINDMIEAWDVFID
MPEIVGYMRYNYEKWKEYNEQGISTIQDIEKLQQHPEMQILRLP
>A0A5H6LQF5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Havana|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A4Q5VBR7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MDVAVVKTGVSTKRFIQISDCHLGPLTSETLLGLNTDESLHDVLALILNKEPRFDYMVCT
GDIASAGHENCYRRFIDIVHQYFSQPFAWLPGNHDSTSIMSHLSLPELPESRAIDLGNWL
VILLDSVVPFKVHGNFEQSELDYLERMLTANPDKHIMVMLHHQPVLVGSEWIDQYILRNA
DSFFAMLDRFPAVKAVVWGHVHQDFNSERNGVKLIATPSTCVQFKPNCNEFTVDTLMPGY
RWFDLNDDGSLVTGIERVTGKQYIIDYKSAGY
>A0A1Q5U947|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus thuongxuanensis|TrEMBL
MKKINPSTLSHLMFIILLFLSTFSIRAFSSTFISIKNSTDSILELDSSSLKNGTWSTKPP
PKILTSERVNFMFDNSRMNNTEGTTVYKASDGAKITIYWNIPFRGKNSYDITTNKQDSYL
TGYSLIHGENTGIRVTFLKKHLTRNYKVIVMSDPQPWRLETGDPNAFANEEPWKNRNRNV
VKSINELHLQGLVDFGIINGDMTEFGRQNTRDDFYLIYNKLLFPFYFGLGNHDYQNNVND
CTESWHFDFSKNACARWSVDNMASEINDNYQNELLLNFNSDYNNDKHSGSLAYSWDFGNI
HYVQLQNYPTYWVTLDHYAAPTIYIKNSMAWLKTDLTKAYSRGKASILNFHDGTQNFIQN
STDEQKKEFKNLIEKYNVMAVFIGHTHQVNESNKNGGDPIFGNARIYNSGALFQGDFLLM
NVRNKCIDVSVYNGRDGTPRKIQDFQGTCGKLTHQLNQ
>A0A6N3C2X9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter agglomerans|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAEHRDCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
KWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLTKFPRVKHLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLAGAQFRPDTASEGY
>A0A673GY13|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sinocyclocheilus rhinocerous|TrEMBL
MEPPPCAKKSLSLSLPVPREGQATLKPPQHLWRQPRTPIKIKHRGYSDTDRHHHRQIERS
NAMDTSDRPGLKKSRMSWPSSFHGTTSCRAGNGRAGGGGWGYDGENGPSSQASPGLVLHP
SFPQSQRRESFLYPVSLNTQHSLTVYCLNFSFLKGLRGRSFIPESPCNETYQQLARETLE
ELDWCMDQLETIQTHRSVSEMASNKVFLQLLAVASVLPSLVSVEQGCPNLFLRATVFGPR
HPSPSAWAYWRPLTRHPLPAPHLCPEATGWPTPPATAPCRGEEGQSWSLGQLFFISTLYV
LSMICNALKERDLLKTFRIPVDTFITYVMTLEDHYHANVAYHNSQHAADVTQSTHVLLST
PALDACDPEFSFIPVLLFFTDSELALMYNDESVLENHHLAVGFKLLHEENCDIFQNLTKR
QRQSLRKLVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLMLDHYNDRIQVLRNMVH
CADLSNPTKPLAVYRQWTERIMEEFFRQGDKERERGMEISPMCDKHTASVEKSQVGFIDY
IVHPLWETWGDLVHPDAQEILDTLEDNRDWYQSTIPQSPSPPPDGPDNELESCTNKFQFE
LTLEGEPGQDCAPMGPTPSYPLPRSATSARWPCAFLNHQLQLWSCCEAMHRGTGVSAFVF
IFDCLFLFLSNLSPSNMVLVPAWSIRIVFVIVPALICQSSSVAFKPTEHLGPTLDLSPSL
LTNCPHYPCE
>A0A2J8NHF8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pan troglodytes|TrEMBL
METLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTF
LDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLA
KELEDLNKWGLNIFNVA
>A0A8C8YHY3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Prolemur simus|TrEMBL
ATFFQLKILTTLLWDSVAVAEVQFGPMRFHQDQLQVLLVFAKEDNQCNGFCRACEKAGFK
CTVTREAQAVLACFLDKHHDIIIIDHRNPRQLDAEALCRVDREELSVMPFLAAGFTRRYI
ENPSIMACYNELLQLEFGEVRSQLKLRACNSIFTALEKSQEAIEITNEDHIIQYANPAFE
TTMGYQAGELIGKELGEMPINEKKADLLDTINSCIKIGKEWQGVYYAKKKNGDNVQQNVK
IIPVLGQGGKIRHYVSIIRVCSSNNKAEKISECVQSDTNTDNQTGKHKDRRKGSLDVRAV
ASRSGETSSQRRHSSMARIHSMTIEAPITKVINIISAAQESSPMPVTEALDRVLEILRTT
ELYSPQFDAKDGDPHASDLVGALVSDGLRRLSGNEYVLSTKSSQQVSSNIITPISLHDVP
PRIARAMENEEYWDFDIFELEAATHNRPLIYLGLKMFARFGICEFLNCSESTLRSWLQII
EANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPVDKVAALIAATIHDVDHPGRTS
SFLCNAGSELAILYNDIAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQGIIDMV
LATEMTKHFEHVNKFVNSINKPLAALEESEETEKNQEAINSMLRTPENRTLIKRMLIKCA
DVSNPCRPLESCIEWAARISEEYFSQTDEEKQQDLPVVMPVFDRNTCSIPKSQISFIDYF
ITDMFDAWDAFVDLPDLMQHLDNNFKYWKGLDERKFRSLRPPPE
>A0A223MEJ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinobacillus pleuropneumoniae|TrEMBL
MSSFYSLGKKEPVVRLLQITDPHLFTSESETLLGVNTTDSFQAILDQIRQSEFEYDLVLA
TGDLIQDHNPEAYHRFAQMVKPLAKPIFWLEGNHDLQPHMGLYLAKYPHISPAKHILAGE
KWQIILLNSQIAGAASGHLSFGQLSWLDKKLAEYPDRYSLVVLHHNILSTRSAWLDQHCL
NNSEQLAEVLRHYPNVRAILHGHIHQEVDDIWQNYRIFATPSTCIQFKPNCDDFTLDLLP
QGWRELNLFDDGHIETQVKRLNSNEFLPDFKSKGY
>A0A3A2I0F8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. PID23_8|TrEMBL
MQSSSDSIKLLQITDTHLFAADEGSLLSVRTADSFTSVVQEVQHRQVPFDYILATGDISQ
DHSAESYQRFAEGIAPLEKDCFWLPGNHDYKPNMGSILPSLQIQSVEHRLLGECWQLVLL
DSQVVGVPHGRLSDQQLSLLEEKLTENPQRYTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QIVERFENVKGILCGHVHQDMNVLHNGIRVMATPSTCVQFKPNSDDFALDVQSPGWRELE
LHRNGEITTQVSRLADGLFLPDFASNGY
>A0A6C0U0V7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kineobactrum salinum|TrEMBL
MSEFRHLRHHAGASGDTVHLLQLTDTHLEREFGGKLLGMDTDHSLQAVISQAARERPQVD
ALLGTGDMSNHGSLEAYRRLKSYFAQLCGQQFWLPGNHDDRSLMALVDDAGVLLSNDIRI
GAWQLVLLDSQIPGRVGGRLGPGQLALLRAALDEGAAAGLYSLVCLHHQPVAIGSRWLDR
QMVADADEFFATLAGYPRVRGILWGHIHQQVDREWQGRRLMASPSTCVQFAPGSDNFKAD
AAAPGYRWLELHSDGRIDSGISRVEDQHFEVDLESGGYL
>A0A093CL51|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pterocles gutturalis|TrEMBL
FDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSS
LPSEQHGDDLIVTPFAQVLASLRSVRNNFTLL
>A0A6M3NKQ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Worthington|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2H6AHC1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR36|TrEMBL
MSLRLAQFSDLHLPYWPARWRKSDWNLKRLAGWINMRWLFRSELFELAETVTQALVRDVQ
QRRPDAVVLCGDVACLGFEEEFAKAASLLRPLLESFPGVAVPGNHDHYVADSVRSGAFER
HFALWQQGLHTEEGTYPFAVVLDSLVLLAANSAQPTRWPWDTRGQVGAEQLRHLQDLLAL
PAVRSRPCLLATHYPLLRANGSPETYFRRLTDADALAELLARHHVLAWLHGHRHHPYVHL
PDVQRGFALLCSGSATQRLVWSYYELEWHLPSLIVRRRAYWLPTDEFVEVSQQEIPLAHL
P
>A0A3B4A8V9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Periophthalmus magnuspinnatus|TrEMBL
MIPRTCRALTDPLPPCLAPTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKVR
HKSTQKHPNVHKKLLRTVVPNHRAGDRYRAVMHLLPGRTKTVHNLSATASSPT
>A0A4T2A1P8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas leptonychotis|TrEMBL
MPGAPIKTTAVDRSVLLVQLSDSHLFADAAGKLLGMDTQDSLQRVIERVLQEQPQIDLVL
ASGDLSQDGSAESYQRFREATAVIPAPARWFPGNHDEVPAMQAACHGSDLLDPVIDLGNW
RVTLLDSSIPGAVPGYLSDQQLALLERALSEAPERHHLICLHHHPVSIGCKWMEPIGLRN
PDALFAVLARFNQVRAVLWGHIHQELDQQRGPIRLLASPSTCVQFAPGSEEFQVDKTAPG
YRWLRLFDDGRLETGVSRVTGITFEIDYTIKGY
>A0A0F5AQT7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salinivibrio sp. KP-1|TrEMBL
MQSCQIDNADGDCIRLLQITDTHLFASEQGSLLGINTLRSYHAVLDAISATDPTFDAIIA
TGDLSQDHSALSYRRFVDGIARWSQPCFWLPGNHDYQPEMSAVLQSNTLRSCPQVLLGEH
WQMVLLDSQVAGVPHGELSQAQLNLLDTHLSAHPERHALVLLHHHPLDAGSTWLDQHKLA
NREAFWQVMARHPQAKIVVCGHIHQALDVRYQGARVMAAPSTCIQFMPDSHDFALDNQNP
GWRWLELYADGRVETQVARVTGQHFRPDFDSSGY
>A0A6L5HL04|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. FSL R10-2245|TrEMBL
MPNASTPTTEDSVLLVQLTDSHLFADADVSLLGLNTAQSLQQVVDKARAEQGQVDLLLGT
GDLAQDGSVAAYQRFRQVSEPLCANARWLPGNHDRLAQMREATVQTRLLDPVVDIGNWRI
ILLNSQVPGATPGYLGDDQLQLLAQAVSEAPQRHHMVCLHHHPLPVGSKWIEPIGLRNAK
KFWAVLDRFPQVRAVLWGHIHQPFDQIRNNVRLLATPSTCVQFTPGSTDFDVSGEAPGYR
WLRLHPDGALDTGVSRLDNFVFTPDYSANNY
>A0A3D3HL84|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Morganella sp.|TrEMBL
MEIPLHLTVADGAAVRILQITDTHLFAGETETLLGINTLHSYHAVLDAIKKQQLPTDLIV
ATGDLVQDQSIRAYQRFTQGVTRLPAPCVWLPGNHDYQPSMARELADAGINPAKHILLGE
QWQVLLLDSQVQGVPHGELSEYQLTWLDERLAQYSDRHTVVMLHHHPLASGCTWLDQHSL
RNSHELADVLVKYQNIDAILCGHIHQDLDMIWNGMRVLATPSTCVQFKPHCTTFTLDTVA
PGWRYLELTTGKQPTLKTAVHRLDTDEFSPDLGSEGY
>A0A0Q4N7L8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia sp. Leaf53|TrEMBL
MESLLKLPVASGSRVRILQITDTHLFAGKHETLLGVNTWASYDAVLDAIAEQQRHIDLIV
ATGDLAQDHSPEAYQHFAEGIARLPAPCVWLPGNHDFQPAMFNTLAATASINDQKHVLLG
EHWQVVLLDSQVFGVPHGELSEYQLEWLESVLASAPERHTLVLLHHHPLPSGCSWLDQHS
LRNPHMLDCVLQRYPLAKNLLCGHIHQELDLMWHGRRVLTSPSTCVQFKPHCTNFTIDAL
PPGWRWLDLYDDGRLETEVERLTTQRFSPDLDSEGY
>A0A8C8FIE4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oncorhynchus tshawytscha|TrEMBL
LYSGSSTETILTFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYD
LSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQQDRASNKRSPMCN
QQPPITKSSFSGKTNTHTHTVLQPSELI
>A0A3S4UA18|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas encheleia|TrEMBL
MRLLQITDTHLFASAEGRLLAVRTAESLAAVLARVQDNAHPFDLILATGDLSQDHSPESY
LRFATMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGDHWQVILLDTQVRGKP
HGVLGDHQLATLDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNADDLFAVLARHPQ
QKTILFGHVHQEFDEVHQGVRLIASPSTCIQFKPLSDGFALDESGPGWRYLTLHPDGRIA
SQVWRLPVGQFVPDPHATGY
>A0A8J7C404|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Iningainema tapete BLCC-T55|TrEMBL
MNQVSPILVGQLTDLHLFADENQKLIGMPTALSLQAVIERLRVLKPELDLLLLTGDLSGD
STHQSYENLLNLIDQVQIPTYWIPGNHDCAIAMNQVLNLRLVSQRKSFERGGWNFILLNS
SVPGCVHGYLSVKTLQWLDSQLKMVGSKPTLVALHHPPFYINSDWLDTSRLQNAEEFFAI
LDNYPQVKIVLFGHIHQEFHYQRHNINYLGTPSTCIQFKPESSIFAVDKKPPGFRLLKLY
PNGTWETQVERVPYYHAVDLAATGY
>A0A5C4L494|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas jessenii|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEADGTLLGMNTRESLQKVIELVLRQRPRIDLILAT
GDLSQDGTLESYQQFREMTAQIDAPARWIPGNHDEPQIMAQAAVQSALLESVVDVGNWRV
TLLDSAVPGSVPGYLQDDQLQLLARSLSEAPERHHLVCFHHHPVPVGCAWAEPIGLRNPE
AFFDVLDRFPQARAVLWGHVHQEIDRERNGVRLMASPSTCIQFEPGSHDFKVGEQAPGYR
WLRLLPDGRLETGVERVTDFQFTVDYGSEGY
>A0A5J5DI38|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Etheostoma spectabile|TrEMBL
MAPLRLNAIRCIKHGCRMSPDSSPVLCRIGANSPQSRDYDYRSTVEGTLSDDSPPSPDTP
SQLVAATDSVWPSQAARQTYAHMFSASDCDFDSLPVHPGAVVTCWLLLSELSRSRNSTEI
HDSCVRAADDYLSLERIARYRHACSNGSPFATNKPIDIKPRGRRGTLADEKPHLDSTELE
QCSQPSVVFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPK
SMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRASNKRSPMCNPPPI
TKTTFTVRLHCRAVPVHSLAAALRLCSRVASPSAGV
>A0A383S1W1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas reidholzensis|TrEMBL
MPQPNHPPAPLHVVQLTDAHLFADPAGTLLGLNTRDSLRHVIAQVQREQPQIDLLLCTGD
LTQDGSVAAYQAFRQMTAAFAVPTRWLPGNHDEARVMAEVAQGSDLVQAVTDIGGWRIVM
LDSAVLGATHGLLADAQLALLDDALATAGERHCLVCCHHQPVDIGCAWIEPIGLRNADAL
LQRVRQHAQVRAVLWGHIHQAWDELRDGVRFLATPSTCIQFAPHSEDFKVSEEQPGYRWL
RLHADGRLETGVERARDFEVKLDFDSAGY
>A0A2S0VH34|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacteriaceae bacterium S05|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVFLGD
HWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A5C2M4F5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Thermosynechococcus sp. CL-1|TrEMBL
MNDPFHLIQLSDLHLFATDEGRLLGLPTAQSLAAVLGVIHRHAPAALLLTGDLAQEPVAT
TYDRLATAFRDFTCPVYWIPGNHDEPRVMLPALERPPLRGDRQINLGTWQGLLLSSQADG
KVHGELRPETLSWLEATLSRAGDRPTFIALHHPPFETGAPWLDSSRLQNPEHLFAVLDRH
PQVKLVLFGHIHQEFATERQGVTYLGCPSTCIQFLPRAPEFSLEPIGPGFRHLLLYPDGT
FRTHIERVEIPLTLDFSAKGY
>A0A2N4UR72|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium carnosum|TrEMBL
MQTYSLPQTNPESVVLLQITDTHLFANGSGTLLGVATKDSFHAVLAGVDIAARHFDAIVA
TGDISQDHTPYSYQRFADGISRWSQPCFWLPGNHDFQPTMQSILPSEQIKPQQQVLVGEH
WQMILLDSQVKGVPHGELDEAQLVLLDTALACYPERHALVLLHHHPLEAGSAWLDQHKLH
DNSGLWNVIDRYPQVKAILCGHIHQDLDRTYHGVRVLATPSTCIQFMPDSDDFALDHNNP
GWRYLELTKDGRIITSVHRISGDQFKPKLDAEGY
>A0A7J8KE02|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rousettus aegyptiacus|TrEMBL
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQ
KDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVDTENEDHLAKELEDLNKWGLNIF
NVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAAD
VAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDES
VLENHHLAVGFKLLQEEHCDIFQNLSKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMV
ETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKE
RERGMEISPMCDKHTASVEKSQVSNIRFSKFL
>A0A1A8EXB0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothobranchius korthausae|TrEMBL
MSSNELSVEMDSCIRTFKEHMHLELEPPKMPGVMGGKRGATSPKLSPRSSPRLFRKLMVN
KSIRQRRRFTVAHTCFDVENGPSASCSPLDPQASPGSGLVLHTNFPGHNQRRESFLYRSD
SDYELSPKSMSRNSSIASELHGDDLIVTPFAQVLASLRSVRNNFTILTNVQCPSSKRSPA
ATTQPPITKVFLPDEAYQKLAMETMEELDWCLDQLETIQTY
>A0A0F2I775|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. S234-5|TrEMBL
MQHTTSDTSSIKLLQITDTHLFATDEGSLLSVKTLQSFQAVVEQVMQRQVAFDYVLATGD
ISQDHSAHSYQHFAKGIAPLQKPCFWLPGNHDYKPNMSSVLPSAQITAPEYVALGEHWQM
VLLDSQVVGVPHGRLSDSQLILLEEKLASNPSKHTLILLHHHPLLVGSAWLDQHTLKDAE
VFWEIVYRYPNVKGIVCGHVHQDMNRMHRGIRVMSTPSTCVQFKPNSDDFALDNVSPGWR
ELQLHADGEITTQVQRLSAGSFLPDFTSSGY
>A0A1M7YU33|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio quintilis|TrEMBL
MDISLYSEPGETVKLIQITDTHLFSSDEGCLLSVNTADSFKTVVEEITRRNVEFQAILAT
GDISQDHTDASYQRFADGIQGLKKPCLWLPGNHDEKSLMSHVLPSPQIFQPQHVCIGAHW
QIVLLDSQVTGVPHGRISDEQLAYLDDVLSGTADKHTLVLLHHHPLLVGSAWLDQHSLKD
RDQLWQVIHRYAHVRAILCGHVHQVMERDYYGVKVMSTPSTCVQFKPGSDEFSLDPLSPG
WRELELHPDGRLTTRVSRLENGLFLPDFSANGY
>A0A4Q7D583|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cryobacterium sp. SO1|TrEMBL
MSIRTAEYPRPDYFLLHLSDTHLLADGNRLYGSVDSAAHVERLFADVEASGGRPNAIIIT
GDLADKGEPHAYAQLRGIVEPAAARMGAKVLWVMGNHDNRANFRTELLDQEPSQAPIDHV
DYVGGLRIITLDTTVPGSHYGEISERQLEWLGEQLKVPAPDGTILAMHHPPVPSMLDLSV
AVELRDQASLAQVLRGTDVRSILAGHLHYSSTATFAGIPVSVASATCYTQDLNVPVGGTR
GRDGARAFNLVHVYADTVLHSVVPLGEYEPLDYVDAAESARRLAASGIEIMAAGSLPAYR
EPPMTTPIRILR
>A0A498TUY6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacillus safensis|TrEMBL
MKYAIGFTAAIAAVTTGVCVTAKMVKTAKQNNIKKHYFTIEALQSDRPAVIFFISDTHRR
LISDTLLAEIRQEEPDVIMIGGDLAEKGVPYARIEENVKRLSRIAPVYFVWGNNDHELHQ
QRFKEILHAYDVTTLQNETAVWNFNGQRIKIGGIDDIRLEKADYEAIRPEFVKEDVNILL
SHNPDVHHLMSEEEGIDLVLSGHTHGGQIRIGKFGPYEKGRTGQVKGAFFLISNGYGTTK
IPMRLGAEPETHLIYLMPLKTR
>A0A498MQT9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Labeo rohita|TrEMBL
MEPPPCSKKSLSLSLPVPREGQATLKPPQHLWRQPRTPIKIKHRGYSDTDRHHHRQIERS
NAMDTSDRPGLKKSRMSWPSSFQGTTSASMSNCAGNKRYDGENGPSPGRSPMDSQASPGL
VLHPSFPQSQRRESFLYRSDSDYDMSPKTMSRNSSINSEGHAEDLIVTPFAQVLASLRTV
RSNFTILANVTTPTNKRSPVTSQPTVPPATLSGTVASKMHYSIRNSGAIWETDETYQQLA
RETLEELDWCLDQLETIQTHRSVSEMASNKPFPLAFTCVVVVFLPPPVIAQRSRLFDSPS
LSVPPLAAFPPSVWIGVSSAQLLG
>A0A0L7YVL1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio alginolyticus|TrEMBL
MNVSPTLDNTDSIKLLQITDTHLFAPEDGSLLSVNTVDSFNAVVTEICAQNVVYDAVVAT
GDISQDHSAESYLRFADGIAALDKTCFWLPGNHDFKPNMGSVFPSAQIQQPEHVLLGKHW
QMILLDSQVVGVPHGRLSDQQLALLDEQLSAYPQRHTLVLLHHHPLLVGSAWLDQHTLKD
SDAFWNVVTQHHNVKAVVCGHVHQNMDKLHHGVRVMATPSTCIQFKPNSDDFALDRTSPG
WREIELLPDGQIKTQVKRLANGVFQPDFNANGY
>A0A679JKH6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium bullatum|TrEMBL
MAGLLNTAAGTIPADPSASVAGRTLRVQVVSDLHVDIVDTRQLRLAPGADLVAVVGDTRA
GAASAFAYLRRHIPAPIPIVAVLGNHEFYGSAIESGLGRAREAAGCLGITLLEDEAAVIA
GVRFLGATLWTDYALFGPAHRAVAMAAARRGMNDHRLISVGRGPERRPFLPGDAAILHAA
SVRFLDATLAVPFDGPSVVVTHHAPHPVCIAPRFGRDPLGAAFASDLSALIDTRRPDVWI
SGHTHHPVDTCLGPTRLVSNPHGYRDECRGTFDPAFVVEIPVTPRMEDLT
>A0A6I9XY23|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Thamnophis sirtalis|TrEMBL
MSSGIGYNRVMSLPSLHLSIRSFEVENGPSPGRSPLDSQASPGLVLHPSFPQSQRRESFL
YRSDSDYDMSPKTMSRNSSIASEAHTEDLIVTPFAQVLASLRSVRNNFSILANVPTPTSN
KRSPLGGQPAVCKATLSEETYQQLARETLEELDWCLDQLEAIQTYRSVSEMASNKVSV
>A0A377N7X2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ewingella americana|TrEMBL
MESLFTLPLVNGAKVRILQITDTHLFAGENETLLGVNTFRSYRAVLDAIKAQNRGIDIIA
ATGDLAQDQSLDAYHHFARGINELSTPCVWLPGNHDFQPAMVDALLEEGIHPSKQLLLGD
HWQVVLLDTQVFGVPHGHLSDHQLEWMERCLQQNPDRFTLIMLHHHPLPSGCTWLDQHSL
RNAHMLAEVLARYPKANTLLCGHIHQELDLDWHGKRLYATPSTCVQFKPHCTNFAIDTAA
PGWRYLDLYPDGRVETQVMRIESDEFRPDSDSEGYE
>A0A1U7CME3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paludisphaera borealis|TrEMBL
MPPIRLVHVSDVHVWRYAINPAQLFNKRLFGMSALLVRRARKFRLERLAHVVDRVVALKP
DHILISGDLTTTALPIEFQAAREALALWLGDPARATVIPGNHDRYTGAAARDRHFEQTFG
EFAGAADYPWIRPLDDRTSILGLDPTRAGWSARGMLPRSQLEAAKALWNERRRAGDRLIV
ACHYPLDAPEPFRDELHPKRMTNAGEVGRWLSTVGPHLYCCGHVHRAWAFGPTEITDQLC
LNAGAPLLRDPSGANPPGFLEIVLDAADVHVDHHYWNGHDWETRPLVHRPGFFERRAF
>A0A6I8VT41|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila pseudoobscura pseudoobscura|TrEMBL
MRNCLPKLTNVFRRKSSAKSSATGNRANHSNDCLSDSDSEQYTAVAMSGGALAIPSPQSD
QPHDNNNKRPPHTDGDSSYSRLISGSHLETVAVAPNVRIRTMDESSFTEMRVEAISGQAP
GPTSGPTPGPARLSVPIPGRNSISLPFAGLGSSKTPEEMELEYEANVKAEGGDIVTPLRR
NTNTTGTRPHSMALNGGRSASLQPEIVEAIRNLDVQGLFFNNLAMEDRDSESDSQCHEDA
VVLRRKVAGLERKSCSLYERRMPKMPKLHLMVAGKKPQPQQQPEDDDDEYKVFQRNLMDL
KYPTVLPPNPQLKALLVFHKSDSICEAVASACQRHQLDVTLVKSKEEALDTLQKSYATAQ
CYHLIIIDARSSKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNR
CVAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANR
ATERLLNMRLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMHVRVV
PVACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRR
TSLAKLTSLPLEAPITKENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIG
ALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKANPIIMELLEESLSWDFDIFKLE
EITDYHPLLYLGMEMFRRFDVFATLNIEENVCKAWLAVIEAHYHKSNTYHNSTHAADVMQ
ATGAFITQLTNKDMMVMDRMEEAMALIAAAAHDIDHPGRSSAFLCNSNSALAILYNDLTV
LENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVF
GGEEPREHNPQSDEETAILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQ
RHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYD
EQGVNTLADVMAMQPPMVKLANSK
>A0A6I8VRX2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila pseudoobscura pseudoobscura|TrEMBL
MIISSQPNLAGSTPTTTATSPVPVPVPVPVPVPATVLVPASVSGAHTSEESVESASAPSG
CNCVGQAGVGVGVGVHVKVDVDGPVGVGARQTPAMEATTTATAEGSRDSLTRPASESELA
VGTGTGTSGTSSSGGGGNNRPGHRKSSLALALTPEDDPMDVYQRNLMDLKYPTVLPPNPQ
LKALLVFHKSDSICEAVASACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARS
SKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMC
SVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLNMRLD
EIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMHVRVVPVACIGSAPTH
LIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPL
EAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGAL
LTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKANPIIMELLEESLSWDFDIFKLEEI
TDYHPLLYLGMEMFRRFDVFATLNIEENVCKAWLAVIEAHYHKSNTYHNSTHAADVMQAT
GAFITQLTNKDMMVMDRMEEAMALIAAAAHDIDHPGRSSAFLCNSNSALAILYNDLTVLE
NHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGG
EEPREHNPQSDEETAILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRH
LPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQ
GVNTLADVMAMQPPMVKLANSK
>A0A679JZU0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hyphomicrobium sp. ghe19|TrEMBL
MTETFTLAHFSDVHLPPVFGSRWQYWNAKRVLGYLNWIRKRRRVHQGEIADKLIADATAL
RVGHIVITGDLINLGLPSEYEAALDWLKSIGSPEDVTVIPGNHDIYSSLHGDPGVARWAE
YMGGENDTLAFPFVRRVGPIALIGLNSAVETPPFFASGRIGSHQLEIAGEQLTALGEEGI
VRVVLIHHPPLPNLAPPRRALSDAAHFAHLLERGDAELVLYGHNHKTRVDWLRSRTKSIP
VVGVASASAAVTYGEEPLASYNLFTFFKSENGLRIRHVVRGIDRPDSPVRKISETVLTPA
I
>B7LGH3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli (strain 55989 / EAEC)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A5J5FYT9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Affinibrenneria salicis|TrEMBL
MESLLTLPVASGARIRILQITDTHLFAGKDETLLGVNTYRSYHAVLNAIVAQQRDYDLVV
ATGDLAQDHSLQAYRHFASGIRQLPSRCVWLPGNHDFQPAMFGTLADEGIAPSKHVLLGE
RWQVILLDSQVFGVPHGELSDYQLEWLERCLASQPDRYTLLLLHHHPLPSGCTWLDQHSL
RNAHNLAAVLLNYPQVNTVLCGHIHQELDLNWHGRRLLATPSTCVQFKPHCTNFTIDNVG
PGWRYLDLLPDGRVETEVFRLAGDEFLPDMDSDGY
>A0A832Q7U3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonadaceae bacterium|TrEMBL
MIPKSRQEPTPTRILQVTDTHLFSHPEGTLVGMNCDEGLRDVLDLVRQRELTAATPPALL
LFTGDASQDNSPASYQRLDALLGSLPLPHYWIPGNHDELALMKAAVGTDNACFRSSIGVG
NWRIILLNSSVAGKVHGCLADAELARLRAAMQEAEEEHLLIALHHNPVPVAAEWLQRHAL
QNPEALFAELDVQPKVRAVIFGHIHHELRVSRKGVTILGSPSTCVQFHPSSRAFALDDLN
PGYRWLDLYPDGRLQTGVHRVEEKRYAIDFSGVGY
>A0A835NG32|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lamprotornis superbus|TrEMBL
MLPTTHCSPGASPATSPRSSPRNSPVFFRKLLMNQSIRLQRRFTPCPLSFHSFDLENGPP
GRGALDPQASPGAGLVLQGTFSHGQRRESFLYRSDSDYDLSPKAMSRNSSIASDLCHRCA
LPRRGHGLSPAARGVSRGGPPEPSPLSRPPGPGQSPNRPQQPDPPAGPRWHQVSRGGWEA
EDAHQKLSRETLEELDWCLDQLETLQTRHSVSEMASNKVRDLVTVTPVGMGDPRAPQDVL
PAPHTADPADHPQFKRMLNRELSHLSETSRSGNQVSEYISSTFLGEDPPPRDKQHEVEIP
SALTKDKEKERRKRPMSQISGVRKLKHSSRLAAAGIPRFGVRTEHEALLAKELEDTNKWG
LDVFKVAEYSGNRPLTAIMYSIFQVSMPPACPCPCARMGTQEPPPASPQERDLMKTFRIP
VNTFITYMLTLEDHYHADVAYHNNLHAADVAQSTHVLLSTPALEVIPGHLRPPRCAWRVS
PMLFPTIPRLSSRTWRSWLPSSPAPSTMLITLGSPTSSSSTPVSWGTGKDLGDIWGPQES
PRGDQWHLTDSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSRKQRQTLRKMVID
MVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPL
ELYRQWTDRIMVEFFHQGDREREKGMEISPMCDKHTASVEKSQVGFIDFIAHPLWETWAD
LVHPDAQELLDTLEDNREWYQSMIPRSPSPPPEGPAVSPANTDKFQFELTLEEEEEGESD
TELEGAESPLDEDNSGSKTPGTDDSECADTKRLSPGPGDRDSPVPRPSDVDNRRALEGTL
PKDGGSGCSVPEGSQGLCLDTEGNVTFLSLGT
>A0A329EE17|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio diazotrophicus|TrEMBL
MSPSIDNPDSIKLVQITDTHLFAPDDGCLLSVNTADSFRAVVKEICSQQVQYDAVLATGD
ISQDHSAESYQRFSESIQMLEKDCFWLPGNHDYKPNMGAVLPSPQIRTEEHVLLGEHWQM
ILLDSQVVGVPHGRLSDHQLALLDDKLTQYPDRYTLVLLHHHPLLVGSAWLDQHTLKDSE
SFWEVVQRHSNVKAVLCGHVHQNMDKEHMGVRVMATPSTCIQFKPNSNDFALDKTSPGWR
ELELCSDGTVKSAVKRLANGVFQPDFDASGY
>A0A7Z1WCB1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter johnsonii|TrEMBL
MTLNNEKNWTIIQISDTHLMDQDHLEFVRMNPEQSFHHVMQHIVERHPQIDAFVHTGDLA
QVPVPRTYQRYLDFIQSLKTPFYQVPGNHDNAEHFPFHQQQNKVHVIHFGPWSMVLLNSA
VKGKIDGWVDEAQLNQLEQILQEFAQQHIVIACHHHPFEMQSKWIDQHKLKNTQDLTAVL
AKYHNVKIVLSGHVHQESWREWHSIQFYSTPSTSVQFKPLSDHFALDEQAPGYRILQLNA
DGSHETHVERVLHAQQKINVEISGY
>A0A427V0Q7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter johnsonii|TrEMBL
MTLNNEKNWTIIQISDTHLMDQDHLEFVRMNPEQSFHHVMQHIVERHPQIDAFVHTGDLA
QVPVPRTYQRYLDFMQSLKTPFYQVPGNHDNAEHFPFHQQQNKVHVIHFGPWSMVLLNSA
VKGKIDGWVNEAQLKQLEKILQEFAQQHIVIACHHHPFEMQSKWIDQHKLKNTQDLTAVL
AKYHNVKIVLSGHVHQESWREWHGIQFYSTPSTSVQFKPLSDHFALDEQAPGYRILQLNA
DGSHETHVERVLHAQQKINVEISGY
>A0A2X2GRZ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia quinivorans|TrEMBL
MESLFKPTVASGARVRILQITDTHLFAGENETLLGINTYRSYHAVLDAILAQQRDFDLVV
ATGDLAQDHSLAAYRHFAEGIARLPAPCVWLPGNHDFQPAMVDALADAGIAPSKQVLVGD
HWQVLLLDSQVFGVPHGELSEYQLEWMERCLQAYPDRYTLMLLHHHPLPSGCTWLDQHSL
RNPHTLGAVLLRYPKVNTLLCGHIHQELDLEWQGRRLLASPSTCVQFKPHCTNFTIDEVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A8E4A9P2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia vermicola|TrEMBL
MDSQLEVTARNSKVVRILQVTDTHLFADTANTLLGINTHQSYHAVLDAILEQNQPIDLIV
ATGDLVQDQSPEAYQHFADGIELIPAPCVWLPGNHDYQPAMVRSLKLAGISSAKEILIGD
DWQILMLDSQLQDVPHGELSEQQLDWMKACLDKQPQRTTLIMLHHHPLPSGCTWLDQHSL
RNSHILAEYLKGYPQVKVMLCGHIHQEMDENWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELTVDEKGHRHISTQVHRLNTQKFSPDFDSDGY
>A0A7K0DW86|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nocardia aurantia|TrEMBL
MSCCGPTRRRLLGALATTAAALPVLTLTGPGPARARGTVIATDLEVVTVTDTTVILTWST
RTVDGTPVAADTEVAVAPADSPATPSLGYSDPEPTPYHYAEIRGLEPGRAYRFEARSGGV
RAAPAANLVTARPGTPETLGVVTTLVPPPGRHLRTLALSNDTHIGETVAGLIRQNLPPGV
SQEPGLPPYPEVMLDALLDDLRRPDRGVHHLLVAGDLTAEATPDQVATVRSRLDGWGAAG
RDWFAVRGNHDRPHTGDDYRACSPNTDAAHHDCWGDRFAPRGSLTEHRVGGLRLLGLDTT
ELDIAGGSIEPEQLDHLRTLLADEPDRPTVVFGHHPVTSESGATNMSGMDFILDRGDAAA
LQSLYRAAPGVFLHHSGHSHRNRRTRPDLPIPVDFVEVGAVKEYPGGYAMVRLYEGGYML
NFHKTRTENAKRWSTRSRAEYLGLEPEYTLGTTTDRNYVVTRDLSGLAAA
>A0A6J2DYL0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Zalophus californianus|TrEMBL
MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRNVQLPPLAFRQLEQAD
LKSESENIPRPTSLPLKILPLIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQAN
FVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFA
ALTNLQDRAPSKRSPMCNQPSINKATITGPPSLQPLLPQY
>A0A2H5V3K1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|archaeon HR02|TrEMBL
MGERVWFWFRLLDGGADKAMMIGHISDTHLGVHAGVEPEREEDHYNAFKDAIDLFIRERV
ELVIHSGDILHEPKPYGTAMKVLIQEVRKLKGRGIPFLFTLGEHDISNVPSTPHPIILQL
QGLGRYIGTGEPYQVGGVTVIGLHKHKRVEWKSLIEKFEKIQRMLPNIGGKKVLVLHQGI
KEAWELGAELSIFELPAGFDYYAMGHIHKSYKRNWGSGLLAYPGATHWVKVDDSGECGVF
IVDLSGDQALAEWVRLPNVRPKLRLEVDVRELDEKVKEITGVDYPSKPCLWLVVKADRPV
SVQSIEQRLSDKFIIKRLQVIPAPTEGKVYASEPEISIDGELRRLAVKAIGDEKVIDFAL
NELLPRLASGDLVNAKEAVWKLWKSWPRDWAGSDSEG
>A0A2H5V427|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|archaeon HR02|TrEMBL
MSEVARRLAVKAIEHGYQLSAEALDRLLRDENPLGLLDELLAWLEARGTSQVIIDRPTLE
VFLASRVARAGAPEEEQPLEIVLESPTYEDLSIEGVSEEQRIYLLSRFQSIRRVFEERGL
GLRPAKELMREEGEGYVVGMVLSIVRRDTHFLVEMEDPVDTWSLIAPTRDRALAAKMEYI
LQDMVVVFRARSRRGLLVASDVYLPDTAGKKQTWRGPDKNICIVSDIHIGSERHASERFR
SFLDWVSSPENEAEKITLLIVNGDLVDGVYVYPGQESELSLKSYAEQFAAAAKALSRIPA
QVKVVYVPGNHEPCRRALPQPPVQIRYRQLLGGGGRIVYAGNPAWIRVGGLKILAFHGQT
LDDVIQAGTLFSYSTLRERSSEMMELLLKARHLAPTLGLSTPILPTRTDYLAVPEQPDIL
CLGHTHVAAYTTYKGTQLVNSGSWQEQTKLQESIGLEPTVGTAVLLNLKSLSIRFLSF
>A0A6L9FV69|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. V32_P6A28T40|TrEMBL
MNVSPSLDPSDNIKLVQITDTHLFAADDGCLLSVNTADSFHAIVQAIIEQKVAFDALLAT
GDISQDHSAESYQRFASEISALQKACFWLPGNHDYKPNMGSVMPSSQLHAPEHVLLGKHW
QMILLDSQVVGVPHGRLSDYQLNLLDEKLAQHPDRYALILLHHHPLLVGSAWLDQHTLKD
SDAFWSVIQRHQNARAVLCGHVHQDMDRTFAGVKVMASPSTCVQFKPNSDDFALDQCSPG
WRELELHADGQVTTQVKRLARGAFVPDFTSNGY
>A0A0Y7N3Z7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYTRFVEMMRPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGKH
WQAVLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELYSDGSIRTEVKRIQQAEFLPNMQEEGY
>B7LQ01|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)|TrEMBL
MESLLTLPLAGEATVRILQITDTHLFAQKHETLLGVNTWESYQAVLEAIHAQQHEYDLIV
ATGDLAQDQTSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
HWQILLLDSQVFGVPHGELSDFQLEWLEKKLADAPQRHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLANFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTQVHRLSDTRFQPDTASEGY
>A0A734WSJ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGERDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A672SRD6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sinocyclocheilus grahami|TrEMBL
MDRTYAVDTGHRPGLKKSRMSWPSSFQGFRRWVCGILKRANVLPNNPRRPVLYSSECTQT
SRPFGKSIHRGIASTSMTLCFTLLLKVLASLRTVRNNFAALTNLQQDRTSNKRSPMCNQP
PLSKASFTGEIVSFAFYTISEMQQ
>A0A622TQF5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSVLQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A6L5BYZ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas frederiksbergensis|TrEMBL
MNISKVTSLLAGLGLLSIASLAHSIENTPRHMVFASDPQYPWTEKSDRREDELDVEFEKR
AKWLVESQFASIADFRKQSGGQSDVPLMINGDMTAFGHGWQRSYINSTLKKYFDKDFLYG
LGNHDYANNVDDCFTNSCAAGSIVDYKEHHEGTVDDFDLKVTGGPLNRLYSGSLAYSKNI
GEVHLVQLNFEPTYEVKISHPLNPTAFNITHALDWLENDLLMARTQGYAIIINMHSPDQW
KGNWDQLKRFKDMVTKYEVTAIFAGHYHEDGGALLYLGNVPTFLSGSASQQTYLIASFSE
DRKLLHVNFVEDNQWQTRELLRTVPVKSIFAQRP
>A0A8C2PKX5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Capra hircus|TrEMBL
VFPGRRSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKS
MSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINK
ATLTGKKDLGDYSFHV
>A0A5J6NW14|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cellvibrio sp. KY-YJ-3|TrEMBL
MRLIQITDCHLGAQQSESLLGLNTDQSLDDVLQLIQTSEVGFDHLLCTGDVASEAHRDCY
QRFETNIRRYFSQPMSWLPGNHDSAELMAANQERLGIQSRLVMLGQWVLVLLDSSVPGQV
YGQLAASELDFLEHALRAHRDKHVIISLHHQPVLVGSVWIDQYIVRNADAFFQLIDAHTQ
VKIVTWGHVHQEFQQQRKGVTLLATPSTCVQFKPKCDDFTVDTQMPGYRWFDLRGDGSFD
TGVLRVTNKQYVIDYKSAGY
>A0A811GVG3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter mucicolens|TrEMBL
MTRILHLSDTHFGTERKAVIEAVLDLARQLSPDLVVLSGDITQRARRSQFAAARRFIERL
ALPVLAVPGNHDIPLFNVFLRVLNPYGNYKRALGPILEPVFENDAVLAIGVNTTRPRRHK
DGEISDAQITRVAQRLRQARPGQLRIVVAHHPVRAKVESDLSNLLIGRERALAAWAQAGV
DLVLGGHIHLPYVLPLTAPTGPAGWIVQAGTTCSHRVRGTVPNSLGVITRTEEDGQQVCH
VERWDYAAGAHAFAPVDKTLVSL
>E9PJ03|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|TrEMBL
METLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTF
LDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLA
KELEDLNKWGLNIFNVA
>A0A290HZX4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sulfurospirillum sp. JPD-1|TrEMBL
MFRLSFAFAAIAVLSLINFYSYKRFLKRLDLFFKIQGVIKWVMIAITLCEICYFLVLRLD
NLDPILYTLFSAMIGVSFMLFCVAILYDLFHIPYAKIPHDYSRRLFIKMVFDVTMLILAF
SYIAKGFLNGMKAPRIKEVDVFIDGLESELSIVQITDVHIGKTLGKSFMDAVVKQVNALD
ADMVVITGDLIDMPVTQIGDKLDSLRTIQSRLGVYYVPGNHEYFYGVHKIMEYVRTLGVH
VLSNRSIVINHTINLAGAMDMSGKRFDFEPPDLKRALLHVKPELPTILLSHQPKIVKEMT
DEKIDLILSGHTHGGQIFPFGLLVLLDQPYLSGLYQHSKHTQVFVSNGAGFWGPAVRIMA
PSEIVKINLKVKKA
>A0A2U2H1G6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia pestis|TrEMBL
MESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTFHSYRAVLDAIIAEQHPFDLVV
ATGDLAQDHSVAAYQNFAKGISRLPVPCVWLPGNHDFQPAMFDALAEAGIAPSKQVLAGE
HWQILLLDSQVFGVPYGELSDYQLEWMERCLIAYPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAILTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDAVA
PGWRYLDLLPDGGLETEVHRLDSDEFCPDMDSDGY
>A0A6G7LNE9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella chilikensis|TrEMBL
MLKEAITYGIPEDKSVRLVQITDPHLFAEPEGQLLGVNTANSLNAVINTIQAVKYPADML
LASGDISQDYSGESYRNFVEAIKPLNLPCHYLPGNHDDPRIMYLHMQGERVYGHRRVLAG
NWQIILLDSTVRGKPGGHMAESELEIIRSAIAAEPDKHVLLVMHHNPVLVDCTWLDQHCM
DNGAQFLKEMGRYPQIKGMLWGHVHQQLDTEYQGEGHKLSLMATPSTCIQFKPLSSYFAL
DALQPGYRLLELKPDGSMLTNVYRIPGERFAPDAEASGY
>A0A6H1FSG8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cedecea sp. FDAARGOS_727|TrEMBL
MESLLTLPVADGGRIRILQITDTHLFAGKDETLLGINTWKSYQAVIAAILAEQHACDLVV
ATGDLAQDHSAEAYQHFAEGISRFSAPCVWLPGNHDFQPAMFSALLEAGISPAKRVHIGE
HWQILLLDSQVFGVPHGELSDYQLEWLERQLAAAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAAELDAALKAWPQVKTLLCGHIHQELDLDWNGRRMLATPSTCVQFKPHCANFTLDTIE
PGWRWLDLYPDGSLTTEVCRLQGCKFNPDTASEGY
>W1EKI8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pneumoniae IS53|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A6V8LUM1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Desulfovibrio sp. FSS-1|TrEMBL
MTNQHPYWIGIGDIHGQTANLARIPELPGADAVIVTGDMTNRGGREEASRVIEAVTRLNP
RVLAQIGNMDRLAAQEMLEASGMNLHGRVVRLAPGLCAMGVGWSAPTPFGTPSEVPDEQL
GQWLREVHARVKDREALLLVCHNPPQGTAADRLSGGAHVGSPAVRAFIEEVQPQVCLTGH
IHEARGEDRIGRTLVVNPGDLASGGYVRLDWDGSALSARVLTAGEAAL
>K8CG32|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cronobacter sakazakii 701|TrEMBL
MESLLNLPVAGGASVRILQITDTHLFAGKNDTLLGVNTWESYQAVLAELHAEQRECDLIV
ATGDLAQDHTPEAYEHFATGIASLPAPCVWLPGNHDFQPAMYSTLQDAGISPAKRVFAGD
NWQVLLLDSQVFGVPHGELSDYQLEWLERMLQAAPERHTLLLLHHHPLPSGCGWLDQHSL
RNAQALDDVLNHYPQVKHLLCGHIHQELDLDWNGRRLMATPSTCVQFKPHCAGFTLDTVA
PGWRWLNLHPDGSLTTEVCRLEGAQFRPDTASEGY
>A0A6J5G2Z4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia fynbosensis|TrEMBL
MLLAQISDLHIKRPGALAYRRVDTAAYLARCVAALNALEPRPDAVIMTGDLVDQGDPEQY
EHLKTLLAPLAVPYFLLVGNHDARIALRAAFPERAELRSGGEFVQYAVDVGPLRLIALDS
MVPGQSAGTLCDARLAWLAAQLDAAGNKPTVVALHHPPFACGISHMDSLRLDPAAADKLA
ALIARHPNVERVICGHVHRPMFVRFGGTIASAVPAPGHQVGLDLRDDGPSAFVMEPPAYA
LHRYDPATGIVTHHAYVERADGPYPFYEPEGALID
>A0A209ADC8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia frederiksenii|TrEMBL
MESLFKLPMASGAKARILQITDTHLFAGEHETLLGVNTFRSYRAVLDAIIAEQRPFDLIV
ATGDLAQDHSVAAYQNFAKGISRLPAPCVWLPGNHDFQPAMVDALADASIAPSKHVLVGE
HWQILLLDSQVFGVPYGELSDYQLEWMERCLVAHPERYTLVLLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGILETEVRRLASDEFCPDMDSDGY
>A0A738AF47|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Abortusovis|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A6I5ZRP1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moorella glycerini|TrEMBL
MFRVLHLADLHLGYRPDLPAPVQEEVYRERNGVLQAAVDLALDPRRGINLVLIAGDLFDN
HRPQASLVEETIRELGRLEAAGIQVITVPGNHDEITYNDSVYRREASRWPGLLVTEPMPA
KVATLKINGDACHLVAMAYTGGVSRVDGPLKNFPPAEGGGVNLAVFHGSLDWDGGERSLP
LDGEALSAAGYDYIALGHIHRRGQRQLGRGLACYAGMVAGKGFADPGTGSWTIVTLGDGP
ARVEQVPAAVRPWRVVDVDVTAFHAPEELEAAIRELIDPGALVQVRLAGTIAFDLDLEGL
QARLDHLCSYLDLVNDTEGWAQELLESFAAEPTIRGLFVRRLQAKLAGAAGPGEAAVIRR
ALWRGLLALKGGCGPCRL
>C0AT80|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteus penneri ATCC 35198|TrEMBL
MRVKQGNLLESQLELSVKHKNTVRILQITDTHLFANVEDTLLGINTYRSYHAVLNAIREQ
GLDVDLIVATGDLVQDQTFEAYQHFADGIATLTPPCVWLPGNHDYQPAMIDALNQAGVLS
AKQVLIGDNWQMLLLDSQIQGVPHGELSDCQLDWLTRCLESQKHRDTIILLHHHPMPSGC
TWLDQHSLRNSQELAERLREHSQVKMMLCGHIHQEMDEMWNGIRLLATPSTCIQFRPHCT
NFTLDTVSPGWRYLEMSLLSDEKGRIETQVYRLEGTEFCPDLDSDGY
>A0A7H9LY30|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGESRVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGSLTTEVHRLVDSRFQPDTASEGY
>A0A5P1R5J6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MHADHPRPVHVVQLTDAHLFADPAGSMLGLKTRESLGHVVAQVRREQPLVDLLLCTGDLS
QDASVASYEAFRELTAPFGVQSRWLPGNHDEARIMAEVAPELVQAVTDIGAWRIVMLNTA
VHGATHGLLGDDQLAVLEAALKGAGGRHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDII
EGYPQVRALLWGHVHQEWDEVRDGRRLLATPSTCIQFAARSEDFKVSEEQPGYRWLRLHA
DGRLETGVERAWDFEVKLDFDSPGY
>A0A729IQE4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. houtenae serovar 48:z4,z32:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A636P090|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Guildford|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>F5S1W6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter hormaechei ATCC 49162|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEKRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGD
QWQILLLDSQVFGVPHGELSDYQLDWLETKLAAEPNRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDGVLAKFPLVQNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLAGAQFRPDTASEGY
>A0A5C1C4I4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter chengduensis|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAEHRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSAPCVWLPGNHDFQPAMYGSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLTGAQFRPDTASEGY
>A0A7V1ERW5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Halieaceae bacterium|TrEMBL
MHQSPHNTHFIEASPDVVRVVQLTDTHLCQAKGGTLLGLDTDQSLQAVIELVQDERPAID
LLLGTGDLADDGAREAYDRLQDYFEEIPCDSFWLPGNHDDRGKMEAVANSATRLCKEIRV
SRWQILMLDSQIPAEVGGELGQAELALLEQMLLSARDEGLHTLVCLHHQPVAIGCAWLDE
QMVADADAFFDVLDRYPGVRGVLWGHVHQQIDRQRNGVSLMASPSTCVQFAPGSVKFKAD
KMLPGYRWLDLHGDGRIETAVSRLSDAHFIVEPDSGGYL
>A0A8C0GBF6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chelonoidis abingdonii|TrEMBL
LWVGSEGHRQSWGFGFKRMLTRELTHLSEMSRSGNQVSEYISNTFLDKQNEVEIPPPTHK
EREKKKKQQPMCQISGVKKLVPSSSLTNSSIPRFGVKTDQEELLSQELENLNKWGLNIFH
VSEYSNSRSLSCIMYMIFQERDLLKTFKIPVETLLTYVLTLEEHYHADVAYHNSLHAADV
VQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESV
LENHHLAVGFKLLQEENCDIFQSLGKRQRQTLRKMVIDMVSRAGPSLQEAQAVSLACLWG
SNTHTWGWEQSRGRVGAVPFSQPCQQSGLLGCGPGGGTGARRLC
>A0A7S9LI70|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fulva|TrEMBL
MPHSNPAGTVNVVHLTDAHLFASPEGSMLGLNTRDSLRHVVQQALREQHDTHLLVCTGDL
SQDASVASYAAFKQLTAGFAAPARWLPGNHDEAQVMAQVAPELVQPVTDIGVWRIVMLDT
AVPGAAHGWLQDAQLSVLEAALRTAGERHCLVCLHHQPVDIGCAWIAPIGLRNADALFAV
LDRHPQVRALLWGHVHQEWDQWRGDLRLLATPSTCIQFAPGSEDFEVSQQHPGYRWIRLH
ADGTVDTGVQRALDFEVRLDFDSPGY
>W8ARC4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ceratitis capitata|TrEMBL
MAAGLVILLVDSGASAGGVICLAGATIWGCIFVMAVVATFRCCGFDSGGGGGGGEKESSL
FFCIKLRRSRPLRRCSQQNGGGDGSGGSGGTVSGINDDPLGHGNMCNQALLNPAQMKNEA
DYDKICSGKKDSIVTVAALGNFTHTVVRRATGSTGTSGTTSSGGASKPEKRKSSIALTPD
DESIERSLMDVKFPTVLPPNPQLKALLVFHKSDNICEVVTEACHRQQLDVTVARTKEGAL
ETLSSTSEEFYHLIIIDARSTKHLDAEYIARSIRHTNGHHFTTIIAVVKKSFFEKDEVLI
ALLDAGVNRCVPETTNLSMCNIELKQILHSIVRPHNVMSTQQALYTALHRLKEVILITDN
HLRIQYANRAAERLLNMRLDEIISKPLADIFVSDVSTIMMHGRKNKEFDEILTVRRKGQE
DVSMHVRVIPVACIGRTPTHYVFNLDVPGSHGDFVATLPQAREAPRGSQHSIRRGSVDVR
SVASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQENCSPDEARLIDKVMEFLKREGLYS
PQMKEIRTDDPIATDLIGALLTGPSLYSSRRSSNDSIIRVSGRQSTCMPAKMKATPHIME
LLEESLSWEFDIFKLEEITEKRPLLYLGMEMFRRFNVFATLNIDENVCKGWLAIIEANYH
SNNSYHNSTHAADVMQATGCFLTQLAAKDMGMDHTDEAIALIAAAAHDVDHPGRSSAFLC
NSRNTLALLYNDLCVLESHHASITFRLTLSDDKVNIFKNLDTESFKSVRSVVIDMILATE
MTRHFEHLAKFVSIFGSDEEPKDIVQSEEESSILIRRMMIKVADVSNPSRQPSYCIEWAR
RIAEEYFTQTDEEKSKALPIVMPMFDRNTCSIPKSQIGFIEYIIQDMMHAWDSFIDMPQL
VTYMQINYSQWKKFEEQGVHTLADVKSKQHSLSVKKSAK
>A0A366IR98|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella putrefaciens|TrEMBL
MLKEAVSYSIAEGESVRIVQVTDPHLFADPEAQLLGVNTSKSFAAVLNTIRAVDYPAHLM
LATGDLSQDYSAESYQQFVKAVTPVGLPCHYLPGNHDDPRIMYLHMQGEQIFGQQRILAG
NWQILMLDSTVRGKPGGNMAETQFELIDEAIAAHPECHTLLVMHHNPIVVNCTWLDQHCM
DNGAEFIARVAKYPQVKGLLWGHVHQCIDTHHNGPHGSMQLMATPSTCIQFKPLSPYFAL
DSVQPGYRLLELKADGSINTKVYRVPGNHFSPDNNSSGY
>A0A4Z0WDT8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Natronospirillum operosum|TrEMBL
MEQAVTPWRVVQITDTHLFGDPTRRLQGMDTQASFAAVNDLVRAERESIDLILGTGDIAQ
DNSEEAYRLFHDEMLKLAPDMVWIPGNHDEAARMRALPFGRDANRKVVDNEHWRIILLDS
SVTRNVHGFLEEEELAFLEDALSTAGKRHVLVTLHHHPIPCGSAWLDNHILRNPEPFHRL
IAASSQVKVVLWGHIHQHVDKIIDGVHYLATPSTCIQFAPHQFDFKLDDKPPGYRWLNLY
PDGHVETDISRVNVHLDVDLDGTGY
>A0A0M3FYW5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus haemolyticus|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENHEFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQSPMDGAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCRYFSLDTLQP
GWREIELHSDGSICTEVKRIQQAEFLPNMQEEGY
>A0A653W4Q3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arthrobacter sp. 8AJ|TrEMBL
MEHIEAEHPRPRHFLLHLSDPHLLGGPEPLYGTVDSEARLIQLFDEVKASGARPEAVIFT
GDLADKGDAEAYVKLRAIVEPACKEMGAQVIWAMGNHDDRANFRRGLLDQPGSDAPVDHS
YFINGLRVITLDTTVPGFHHGELSPSQLEWLARQLETPAPDGTILALHHPPVPSVLDLSV
LVELRDQASLAAVVRNSDVRTILAGHLHYSTTASFAGVPVSVASASCYTQDLNVPVGGTR
GQDGGQAFNLVHVYEHTIVHSVVPMGSAPTVGEYVSPEETARRLEAAGIRIPETTKQRGS
TKLGVPTSR
>G1PVR1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Myotis lucifugus|TrEMBL
SVPKLKSPFTKMSTCNFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSD
SDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNMQDRAPSKRSP
MCNQPSINKATITVFCYQCDKSSMESTEQKTWDLTSTELKQNKWSHFTEPEIKLNSFNHF
LKPQLIHYY
>A0A5M3V182|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter ludwigii|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIRAENRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFVGD
HWQILLLDSQVFGVPHGELSDFQLDWLETKLSAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVQNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHPDGLLTTEVCRLTGAKFRPDTASEGY
>A0A7Y1GBC1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. WS 5018|TrEMBL
MPGAPVTAVEDSVLLVQLTDSHLFAEADGKLLGLSTGDSLARVVELAFAEQPRIDLILAT
GDLSQDGSVASYQRFRQLTERIEAPARWCPGNHDELGAMREAARGSALMEPVLEIGGWRV
VMLDTLVAGSVFGMLRGDQLDLLERALSEAPDHHHLVCLHHHPVSIGSRWMDRIGLRNPE
ALFEVLDRHDNVRALLWGHIHQAFDQSRKGVRLLATPSTGVQFTPRSEDFQVDSAAPGYR
WLRLYADGRLETDVSRVSGIDFEIDYSAKGY
>A0A6G7TJ90|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Leclercia sp. 29361|TrEMBL
MESLLNLTVAGGAPVRVLQITDTHLFANKHETLLGVNTWESYQAVLEAIHAQKRECDLIV
ATGDLAQDQTSAAYQHFAEGIASFNAPCVWLPGNHDFQPSMYSALQDAGISPAKRVHTGD
NWQIMLLDSQVFGVPHGELSEFQLEWLEAKLEANPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLMKFPRVNNLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLQSTQFRPDTASEGY
>A0A7R8NMG7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces sp. KY75|TrEMBL
MAHLSDPHVTTGPSAQAPAAGRRAALHHVLALDPPPECVVITGDLTERGEPEEYASVGEA
LGAFPRPLHLVTGNHDAPEALVGAFGGTRFLGGGTTTTYEVEYPALTVAVLDSKVSGSPG
GRLGPAQLSWLDRVLSRRPGVPAVVCLHHPPVPVGIPFLDAMGLADGPALAEVVAAHPRV
VRVLAGHVHHPVTAAFAGSTVAGRAEHVPAERAGAAGGAARLHRRTRLVPAARGAGGAAR
HGLGHPHRAGGRRVKDRAPGVTRAAPPARP
>A0A7J0AHZ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MKLSRFLLALALTAAPAAMAQRMAVLSDLHVTPGNANEAELRKAVDEINNSNFDFVIVNG
DLGNEGSDAELKNSKEILSLIKHPLFVLPGNHEDTWSQSATKTFVDLWGNDRFVAEFDSL
IIVGINCGPYMKMGDGHIKQEDLHWLKATLDERVKPGKRVLSFNHYPLLDDLDNCSDYLA
ILEEYPVITHINGHYHSFSQYIAGGPDSGSDMPCAMTRALDMRDGKFGYAIVEVSPQWVH
FYNKPIGKPAEAKFAFPAKTKHKKAKRAERPAIKSPEGFAVEKVWADSASIFTRLGFDSK
NVYFGNSLGHARAVNKASGKQAWSVPTGASLFSRPVALKGNKVAIPMHDGIMVLDSRNGR
QTAKHNSKEGPYVADGVITPDGKGYIQGGYKRIERRRPDNGKLIWSYDSIFNYCQAAPAI
DGTDLVFGAWDTNLRSLNLATGRLNWVWNNGKKANMLGPGNVVPVITGDKVFVVAPDRFM
TALDRRTGKQLWRDNSHRYRESLGHSEDNTRIYAKTMDGELVAIDATAPQFKELWTLDLG
LGYEHAPCIILEKDGYVYAGSRRGTVTITRANGPELIASLPLGVSEVNGIDVDPSTGDIY
VSLIEGTIFRIARK
>A0A6J0BG29|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Neodiprion lecontei|TrEMBL
MVVPSRRGSMTSSGSKFYIPNDDVDDVLGISQLLFNYNGSEEEESIAEGLESRIRTLPEE
DGEVCVIKGPQDLKSNLLTSWSPSSTKIMLVFGRDDHQSEVLGSAAKKLGWSVTYSRSTD
TALETFHSRGHDIVVIDHRGSRGIDSDSLCRLIRASGVNPNTVIVALVRKSFLINADQDQ
IMTIGLMGIGFNRTLLECSQENLLANELVNIHASELQPRLHLAAFHALYVAVDRCRDMVH
VTNDRHVVQFANKASERFLGYKPEELLGNKIMDIVSSDNFVLMDQHLRRGREWEGNMNCK
RKSSKTITVNCRIVPFSASGRTPTHYIYVHDTTYLLENMAIGPGNTGTQQMPRGSVHSLR
RGSFDVKSTGSETHRRSSFTKIHNLPLEAPITRVIGILSTALNDMSTTSPELALQMYKAI
ELLKGTELYTPQLREDTRGYDPVTEDLVGALLASPVYARDSRRSSNDSVSRIPTSKTLTN
ASAHRMSLKGYRPPQEIHDMMEKSLDWDFDIFKLEVLSCGRPLVYLGMNLIGLYEGPATL
GCDEKTFFNWLTLVEMHYHADNSYHNSSHAADVLQATAKFMRSERLKMIFDPLDEVTALI
AAAAHDIDHPGRSSQFLCNANNKLAILYNDLAVLESHHAALTFKLTLADDRANIFKGLDR
ESYKVARQNVIDMILATEMTRHFEHLAKFVNVCSNRMAGDSQSEPVSEVIDMTVLLQPEN
ITLVKRMMIKCADVSNPTRPLKACIEWARRIAEEYFRQTDEEKQNGMPVVMPMFDRLTCS
IPKSQIGFVDFIINDMVEAWDTFVDMPELISHMRLNYDKWKEYQEQGISTLQDIEKLQTS
PELQIPRRTT
>A0A084ELF4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Glaesserella parasuis|TrEMBL
MDDSYIFPLSTPIIRILQITDSHLFASDTCELLGVNTTQSFQAVLNMIMKESFEYDLILA
TGDLVQDHNREAYHRFAKMVKPLVKPLFWVAGNHDLQPQMRNALSIYSQIKPEKHILVGD
HWQIILLDSHIQDSPKGRLEFSELAFLKRKLEVHPERYSLIVLHHNILPTNSAWLDQHSL
SNVNDLLATLKAFPKVKAIVHGHIHQEVDAQWNGYRILSTPSTCIQFKPHCNDFTLDAIP
QGWRELCLNIDGFIDTVVKRLDNNNFLPNFKALGY
>A0A452TN87|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ursus maritimus|TrEMBL
MPEANYLLSVSWGYIKFKRIHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKK
KKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYS
HNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVAQSTH
VLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHH
LAVGFKLLQEEHCDIFQNLTKRQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVT
SSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGME
ISPMCDKHTASVEKSQVSNMKFSKFLCSYRTTPL
>A0A2H5UXA6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|archaeon HR01|TrEMBL
MYGGVAAPSSAFLPSVRGRSLPFGPDRGAIYKSELHSHASMVESQIRIVHISDTHITKFG
MHIPEALDKCIYLINTLDPPPDIVVHSGDLTDNGILLDYEMAVEKIKEIRYEVLVAPGNH
DERNYGDSLFREMVGNMDYVTSVGRTAFVILDSGIPDSDNGRLGRARQQRLRNAFENLPG
KTFKVAVFHHHLIPIPYAGRERDILEDAGDVLKAILDLKVDLVLMGHRHVRHAVKVGETL
LVNAGTVSSARTRGRLGNSFNIIDVTEDRQVTVSEMKIPSGELHILGTFRVGTQ
>A0A659KTA4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. E3356|TrEMBL
MESLLTLPLAGESRVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVNFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADSRFQPDTASEGY
>A0A399DVJ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Calidithermus terrae|TrEMBL
MNRRAFLGLLGLGVLGGTGLGGYGLASARGFELSRHRYGLPGLRQPLRVAHLSDLHFGEQ
HPAQAVRRWVAAALAERPDLVVITGDFVDQATRPGALRPLGDELARLEAPLGVYGVLGNH
DYSHSVDNADRRAWLSSLTTELERAGVELLTNRGLRLRPDLYLAGVDDLWHGDPDLAAAL
QGAPRDAATLLLSHNPDLLPQVPEWVSLTLCGHTHGGQVCLPLIGAVHAPSRYGTRFAQG
FHRAPAAGFVSRGLGTTWLPVRTFCDAEVVVFDFEPGGVADS
>A0A3Q2QUV3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Fundulus heteroclitus|TrEMBL
MAVPWPCSQIISNSQLKPPPLNRRVPLESPPHLTPPQSYKQTRLNRNPSSRASWFPSVCF
IWHHFWFSFFFLYFTLCNGVKKKSRSEQSVGPGIISGLRASRFDVENGLSVGRSPLDSQT
SPGSGLVLQGNFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLHGEDMIVTPFAQVL
ASLRTVRSNVAALTHLQDRVVNK
>A0A7R8Z7K7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Timema douglasi|TrEMBL
MASLIEVLLVFPKDDFNSDALWYASEKLGYECHLARTENAAVEVFESRHHDIIIVDNRYP
RVMNGDKVCQNLRAAKGSKFTVIVAVVKRSLAEKDDPIVHNFLAVGYNRIFLETSSLGIC
MNELLTLEKSDVIPRANLAATQAFHLALNKCNELVHITNHEHTIEFVNQAVEYHMGFPRS
AMVGKNLMEMCRLEVNELMVQELQKGREWEGVITWYTRTGERLILSGRVLPFSLPGRPPS
LYVYVHESPTMSEKRSSQSIIPFSQQGFQASAAQRGSITSAGTRRQSLAKLYNLQIQAPI
TRIIELINSAQEEAAEPVVQILDKVIDIVRTTELYTPHMKERPIKLTDPVTSDLISALLM
VRTSLHLGETLIPIKVGSGPRYSPKGTMYLAGSSKMKDLLDTALNWDFDIFSVEQISEKR
PLVHVGMSLFLHFESHLALGCDESTLKNWLTIIELNYHSTNSYHNSSHGADVMQAAAGFL
KTDRLMQTLDSLDRAICLIAAAAHDVDHPGKSSAFLCNSDSDLSLLYNDLSVLESHHAAL
TFKLTMSDERVNIFKGLERDTYKVVRQNIIDMILATEMTRHFEHLAKFVNVFCKGGIQDE
ENAEAKADQMDMLAYSPENMSLIKRMLIKCADVSNPTRPIASCVEWALRIAEEYFNQTDE
EKANNLPVVMPLFDRSTCSIPKSQIGFMEFIIRDMFEAWEEQFLPGCRENLFDKLNHLTS
SPERSVRGNPQTASRMHTLTNAMCSFGSQAANLQQIACSTNKALKKNPS
>A0A4P5R044|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Buttiauxella sp. A111|TrEMBL
MESLLNLPVAGGGQIRILQITDTHLFSGKNETLLGINTWMSYQAVIAAILAEQRHYDLIV
ATGDLAQDHSAQAYQHFVEGIAEIPAPCVWLPGNHDFQPAMFSSLLEAGISPAKQVFLGD
NWQILLLDSQVFGVPHGELSDYQLDWLERKLAGAPERHTLLLLHHHPVPAGCSWLDQHSL
RNAAELDDVLQKFPKVKTLVCGHIHQELDLDWNGRRMLATPSTCVQFKPHCSNFTLDTIE
PGWRWLELHPNGEVTTEVCRLKGAVFNPDTASEGY
>A0A6M2A6F8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chlamydiae bacterium|TrEMBL
MKKDPASLRVAHLSDPHFSRVTYHPSQFLSKRWLGNLNLFLFRRKSYQTDHLGHIPELLD
TLEVEQVFFTGDFSSTALDEEFEAAKAYVESFSMPVSLLPGNHDAYTKEAERSRRFYDFF
PNTSLEKDRIEVTELGKGWWWIGLDCAVATPLFHAYGLFTPEMEAKLEAHLQKLPEGARV
ILGNHFPLYPSFHHTHDLKRNEALQKLLIRYPTVKLYLHGHDHKPYIKEKSTPLVFNSGS
CAHKPDGTFYLFDLFEEELLCQRLLFRKENDTFSWVVDWQKSFLF
>A0A093CUR1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Tauraco erythrolophus|TrEMBL
VTHSMCSVRSFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDL
SPKTMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRSNFTLL
>A0A224X991|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Panstrongylus lignarius|TrEMBL
YRHLAKEKDLRRQAALSECIYTALDKSRDLVIITDHAHLVQYVNTPCMQVVGYNRDELVG
KQIGMLHEATEVASVYRQLERGLEWVGRLKWRTKSADMLPLQTHALPFTPHPSLAVHYVY
LSDNPLQTHISPRGSLPSIRKASYDLKSIISEGSARRQSLAKLYNLPLEAPITKVLSLLC
AAQENASAGVVQMLEQVMDILRTTELYTSHLKAENLRAEDPLTTNLIAALVAQGPPSAVM
PRRSSGDSVVSKKKAPSKRSNIVTMSMSKELKEAMDKISSWDFDVILVEKLSGAKPLVYV
GMKIFTLFGVPKTLGIDERTVYGWLTLMERHYKPGNTYHNSTHAADVLQATALFLLRLRA
KKLLDPLDEACCLIAAAAHDLGHPGKSSAFLTNSGHYLAVLYNDISVLEQHHAALTFKLT
LREERVNIFKGLDRKMYTSARACIIDTILATDMFRHYEHYTKFVTVFNKSPDDNQDAKGE
GKTNEAENNINPEDLMLVKRMLIKCADVSNPTRPLPLCKQWAKRIAEEYFSQTDEEKARN
LPVVMPLFDRLTCSIPVSQMGFMDYIVNNMFEEWDSFIELPEMLYHLRKNYDYWKELHDK
GITGTEDTNEHLESVLPHTILPRT
>A0A8E5X9F6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella sp. SJTUF14523|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>H1LPC4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus sp. oral taxon 851 str. F0397|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNEFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQSPMDGAKHLLLGEH
WQVLLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAEFLPNMQEEGY
>A0A7Y2PVU4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. ANC 5414|TrEMBL
MTLSDYNEIQQDWTIIQISDTHLMNQEDLEFVHINPEQSFHAVMKQIQQQYPNVDAIIHT
GDLAQVPVKETYSRYLAFMQRLGIPFYQIPGNHDNIDLFPFYHNQNQVHAIHFGPWSMVL
LNSAVRGKIDGWIEEEQLQQLDRILSKFQQQFVVVACHHHPFDMHSKWIDQHKLKNTENL
TDILAKHPNVKAVISGHVHQDALNEWKNIQFFSTPSTCVQFKPLSDDFALDEEAPGFRVL
HLKANGELQTEIYRTEKAQQKINVEISGY
>A0A2V5C0H0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. AG1095|TrEMBL
MDSLLTLPAQDGSDIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIEVQQRQYDLII
ATGDLAQDHTVEAYQHFVAGINRLPKPCVWLPGNHDFQPAMVDTLADAGIKSDKHVLLGD
HWQLVLLDSQVFGVPHGMLSEYQLEWLHSALSKYPERHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLQHFPRARNLVCGHIHQELDLDWHGRRVMASPSTCVQFKPHCTNFTIDTLA
PGWRWLTLQPDGTLQTEVNRLQSDMFRPDLDSEGY
>A0A8D0G8B5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sphenodon punctatus|TrEMBL
LFIYFIKLFFLSCSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSD
YYLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMC
NQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTH
LSEMSRSGNQVSEYISSTFLDKQHEVEMPSPTQKEKDKKKRPMSQISGVKKLMHSSSLTN
SSIPKFGVKTEQEDILAKELEDVNKWGLHVFKIADLSGNRPLTVVMYTIFQERDLLKTFK
IPADILITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFA
SAIHHVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQ
RQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHC
ADLSNPTKPLQIYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYI
VHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPASDDQEEGRQGQTEKFQFEL
TLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVGEEVEEEESQTDPC
VLEEDCSPDT
>A0A508TFU6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bradyrhizobium ivorense|TrEMBL
MTAGALASETSDEMRVTKVTVADVGFVADCSGALFWEEQRLLVVSDLHLEKGSSFAARGV
LLPPYDTVATLSRLAAVIARHDPRQVIALGDSFHDRTAHERLSDADREALAALQARRSWI
WISGNHDPALPSDLGGVVATEVAIGPIAFRHEPTGASGEIAGHLHPKARVPTRGRSIERR
CFASDGERAVMPAFGAYTGGLSIRDAAFARIFGSPGFTAHVLGDNRVHAFVASRCY
>A0A7Y8PZM6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. SwsAc6|TrEMBL
MPLINNNDQHKHDSVFDWTIIQISDTHLMDQHELDFVSVNPEQSFHEVMHHIQQQVPHID
AIIHTGDLAQVPVAETYSRYLQFMTGLDIPHYQIPGNHDCTEIFPFHLQQDQAHILHYGA
WSAILLNSAVKDKVDGWISETQLQQLHQLLSDHPQQHILIACHHHPFAMESAWIDQHKLK
NATHLMDVISQHSNVKIVICGHVHQDSMNTWNNIQFLSTPSTSIQFKPYSQTFALDQVLP
GYRVIRLKNNGEFETEVHRVALSQPQINVEISGY
>A0A330M074|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moritella yayanosii|TrEMBL
MGADISKLTVKHNVINLLQVTDTHLFATAKKDLLGVKTQLSYRHVIDAILQNQQPFDAVL
ATGDISQDNTPASYQYFAQHIKRLNKPCYWLPGNHDNIPLMSDALRAEGVLADKYKIVGD
WQIILLDSQLTGSPAGYLAPEQLLLLDEQLSAHPDKYALVVLHHNVYPVGCKWLDQHLLR
NADAFLAILEKHSQANHVLFGHVHQQLDKTYAGIHFMASPSTCFQFKPHCDEFTLDSSAP
GWRYLQLYSDGSINSQVWRLSNNDFNPDLESKGYSYSG
>A0A7K0D1W0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nocardia macrotermitis|TrEMBL
MPSSRVAEYPRPDHILFHFSDTHLIGEGALYDAVDAVERLRGLLAQAEASRITPDAIVFT
GDLTDQGEPDAYDRLRALVEPLAEQLGAPVVWVPGNHDDRAALRERLLDESGSAEPLDRV
HVVDGLRIIVLDSTVPGEHYGEVTDGQLAWLRSVLAEPAPFGSILAMHHPPVPCIQDLAV
TVELREQRRLAEVLRGTDVRAILAGHLHFSTTATFAGIPVSVASSACYSQDLAVTYGGQR
GRDGAQSFNYVHLYPDTVVHSVVPLDHGPTVGQPTSPAEAAQRLREAGIVIPDAARIPHV
LPGRTSTPESDDESVS
>A0A8J2HLG3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cotesia congregata|TrEMBL
MDPYDNYYHLSAKNEDQIQGLIANGDLQSLDQTQEVDWIEKSNFEPSFPDEDDVEYTIPK
GPQDFKSTLSIGALSQVVKILLIFPRDDQQLEVLSTVARNLGWSVSIAKNAEQAVEIFQN
RYHELIIIDRRGHRAPEADTICQAIRSTNYHHSSVILALVKKSFFTTTDNEKIMTLDLLN
IGYSRAMMECSHDIMLSNQLIGIYVSEIQPRLQLAAAHALYVAMDRCKDMVHITDEHHIV
RFVNKASEKLLGYQYDEILGSNLSEIITHENFVLMDQQLQRGREFEAQRRSSLQKLNNLP
LESPITKVMTLLTNAMTEINAANPEIATQIDRAIETLKATELYRPYLKEDTKITNDPVAS
DLVEALLSKPSHYIRDGRRSSNDSMRSVTMKLGNSISHRTLTKNLQGPREIDKLLDRSLD
WDFDIFSLEVLTERRPLVHLGMNLMCRYNVPAKLNCDETILRNWLSVIEYKYHLDNSYHN
STHAADVLQATARFMQSERLQMVLEPLDEVAALIAAAAHDVDHPGKSSQFLCNADNKLAI
LYNDISVLESHHAALTFKLTLSDDNVNIFKNLEKETYKIIRQNIIDMILATEMTKHFEHL
AKFVNICSGTGSDEYYSDGIDMVTLLQPENVTLVKIMMIKCADVSNPTRPLRCCIEWAKR
IAQEYFDQTDEEKKQKMPVVMPLFDRNTCSIPKSQIGFVDYIINDMIEAWDAFIDMPEIV
THMKQNYDKWKEYHNMSVVPLMYRDWWDDFDRPVSRLIDQHFGSALSRDDLFSTWNINRP
RSVFPTSMYYRPWRNLARSNSSGASTIQCDKDKFEVILDVQQFSPDEIVVKTVDNNVIVE
AKHEEKKDEHGYISRHFIRRYILPSCHDPLEVTSSLSSDGVLTITAPKKLLSPNSNERIV
NIVKTGEPATKNEEIRHIVTTEEN
>A0A1B6C1Q8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clastoptera arizonana|TrEMBL
RTDVLVRDEDCDTQVNELAAESNCEPLCHRLQQIKTNSPKQHAFRVLLVFAKDDSACSTL
SGASEHLGFSREVASTLEQALELYQAHSSPPQIVFIDMRFSWFHGEKICRSLRAVKKSNH
VIFVAICKKNVVDKDEKELRSALKLGFNRVLVEPLSITQCVCELVQLAHGQLDLHSILAQ
NEAIYLALDKSRDLVLVTDSLHVIQYVNRTWCQVLGYKSEDLIGRSLHSFHQLGNMDPVT
RQLEKGFDWEGKISWRSKSGENITLQCRAMPYQAIGSEPTHYVYVQDNPLENHIYPRGSI
PSIRKGSYDLKSINSEGAQSARRQSLAKLHNLPLEAPITRVISLICAAQENSTGQVVQIL
DKVVDILRTTELYSSHLKADNLRCEDPVTSDLIGALITQGPVPVSTTRRSSNDSAAVKAQ
QAGLSGNKPIFSMSASPQLKELLDTSLQWDFNIFKLEEITGKRPLVYLGMNLLMHFDVHK
TLGCDEKTLYNWLTVIERNYHLSNTYHNSTHAADVLQAMAGFLEKERIKRLVDELDEACC
LIAAATHDIDHPGKSSAFLCNAGNELALLYNDVSVLESHHAALTFKLTLRDDRVNIFKGL
ERDTYKVARQSIIDMILATEMTKHFEHLAKFVSVFNKPSPTSEDGNCDNRSPSDCGGDIS
MLTNADEVNLVKRMMIKCADVSNPTRPLKMCVEWARRIAEEYFTQTDEEKANHLPVVMPM
FDRTSCSIPKSQMGFVDFIINDMFEAWDAFIDMPEMLYHLRSNYQYWKDLEEKGVTSLGD
ISLKQPCSLSPIPNLPNIPEKHSNAY
>A0A212C8H9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cervus elaphus hippelaphus|TrEMBL
FKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGV
KKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTI
FQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEVHL
VSKPSRTLTCHSKWFFNFHTKGHAGQTIIGFLEILLNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQG
DRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRE
WYQSTIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSK
TLCTQDSESTEIPLDEQVEEEAVAEEEESQPEACVIGDPSPDT
>A0A1B6D166|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clastoptera arizonana|TrEMBL
RTDVLVRDEDCDTQVNELAAESNCEPLCHRLQQIKTNSPKQHAFRVLLVFAKDDSACSTL
SGASEHLGFSREVASTLEQALELYQAHSSPPQIVFIDMRFSWFHGEKICRSLRAVKKSNH
VIFVAICKKNVVDKDEKELRSALKLGFNRVLVEPLSITQCVCELVQLAHGQLDLHSILAQ
NEAIYLALDKSRDLVLVTDSLHVIQYVNRTWCQVLGYKSEDLIGRSLHSFHQLGNMDPVT
RQLEKGFDWEGKISWRSKSGENITLQCRAMPYQAIGSEPTHYVYVQDNPLENHIYPRGSI
PSIRKGSYDLKSINSEGAQSARRQSLAKLHNLPLEAPITRVISLICAAQENSTGQVVQIL
DKVVDILRTTELYSSHLKADNLRCEDPVTSDLIGALITVSKLSHQGPVPVSTTRRSSNDS
AAVKAQQAGLSGNKPIFSMSASPQLKELLDTSLQWDFNIFKLEEITGKRPLVYLGMNLLM
HFDVHKTLGCDEKTLYNWLTVIERNYHLSNTYHNSTHAADVLQAMAGFLEKERIKRLVDE
LDEACCLIAAATHDIDHPGKSSAFLCNAGNELALLYNDVSVLESHHAALTFKLTLRDDRV
NIFKGLERDTYKVARQSIIDMILATEMTKHFEHLAKFVSVFNKPSPTSEDGNCDNRSPSD
CGGDISMLTNADEVNLVKRMMIKCADVSNPTRPLKMCVEWARRIAEEYFTQTDEEKANHL
PVVMPMFDRTSCSIPKSQMGFVDFIINDMFEAWDAFIDMPEMLYHLRSNYQYWKDLEEKG
VTSLGDISLKQPCSLSPIPNLPNIPEKHSNAY
>A0A1V0L8W2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kosakonia radicincitans DSM 16656|TrEMBL
MESLLNLSLAGESRVRVLQITDSHLFAEKHETLLGVNTWESYQAVLEAIQAQQRPCDLIV
ATGDLAQDHSAAAYQHFAEGIARFTAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGD
HWQILLLDSQVFGVPHGELSEFQLEWLENKLSDSPERHTLLLLHHHPLPSGCSWLDQHSL
RNAGELNNVLQRFPKVRHLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELYDDGTLHTEVCRLESTQFRPDTASEGY
>A0A8I0GFI1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas balearica|TrEMBL
MPGAPLTTAEDSVLLVQITDSHLFAEADGRLLGLDTHDSLGKVVDLVLAEQPVIDLALAT
GDLSQDGSVASYQRFREQSSRLCAPIRWCPGNHDELTAMRAVADPERLLEPVAEVGAWRV
VLLDTLVPGAVFGRLAEEQLTFLERTLRQAPDRHHLICLHHHPVAIGSRWMDRIGLHDAE
ALFEVLDRHSNVRALLWGHIHQEFDGWRDGVRLLASPSTGVQFAPGSEDFQVDTRAPGYR
WLRLHADGRIETGVSRVSGIAFEVDYSVRGY
>A0A1M5YGT8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio aerogenes CECT 7868|TrEMBL
MKAVLNEVRLNKDRNRCVDLDISLYSEPGETVKLIQITDTHLFSSDEGCLLSVNTADSFK
TVVEEIIGRNVEFQAILATGDISQDHTDASYQRFADGIKDLKKPCLWLPGNHDEKSLMSH
VLPSPQIFQPQHVEIGAHWQIVLLDSQVTGVPHGRVSDEQLAYLDEVLSRTSDKHTLVLL
HHHPLLVGSAWLDQHSLKDRDKFWQIIHRYPHVKAILCGHVHQVMERDYYGVKVMSTPST
CVQFKPGSDEFSLDPVSPGWRELELHPDGQLTTCVSRLENGLFLPDFSANGY
>A0A5E7T3R5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPRVPTLTTADPALLVQLSDSHLFAEAAGTLLGMNTRDSLQHVIELVRLQQPRIDLIIAS
GDISQDGTLESYQQFRDLTRQLDAPARWIPGNHDEPRIMAEAAVQSALLEPVVDIGNWRV
TLLDSAVPGSVPGYLEVEQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIERERNGVRLIASPSTCIQFEPESEDFKVGDQAPGYR
WLRLLPDGELETGVERVTGFEFQVDYGSDGY
>A0A386Y337|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLNPDAPALLVQLSDSHLFAEADGTLLGMNTRESLQRVIELVRQQQPKIDLLLAT
GDLSQDGTLESYQQFRDLSAQISAPARWIPGNHDEPQIMAQATTGSALLEPVVDVGHWRI
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPNRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFQVSEQAPGYR
WLRLHADGRLETGVERVEGFAFTIDYGSNGY
>A0A5E7KQL8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFADADGTLLGMNTRESLQKVIELVLGQQPQIDLVLAT
GDISQDGTLESYQQFRQMSTQIDAPARWIPGNHDEPMIMAQAAVQSTLLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDDQLQLLARSLSEAPERHHLVCFHHHPVPIGCAWAEPIGLRNPD
AFFEVLDRFPQARAVLWGHVHQAFDRERNGVRLMASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGRLETGVERVSGFAFTVDYGSNGY
>A0A5E7G2P6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPRVSTLTTADPALLVQLSDSHLFAEADGTLLGMNTRDSLQKVIELVRLQQPRIDLIVAS
GDISQDGTLESYQQFRDLTRQLDASARWIPGNHDEPRIMAEAAVQSALLDPVVDVGNWRV
TLLDSAVPGSVPGYLEEEQLQLLARALSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFSVLDRFPQVRAVLWGHVHQEIDRERNGVRLIASPSTCIQFEPGSDDFKVGDQAPGYR
WLRLLPDGGLETGVERVTGFEFQVDYGSNGY
>A0A5E7UKZ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MFHIYLTVAYLYVLWRVIVPLPVGRGWRALLAVGLLIISKYHLILIAVYGTMFSPEVPRA
AVLVAGWLFCAFVLVMVLTLVTDLICAALAIRRTVVMKDVFDGRLRSAIALAALLLSAVG
VYQAVQVPGVHRVEVTVQHLPRSLDGLRIVQLTDLHISRLFQADWVEGVVSRANALNADA
ILITGDLIDGTVEARKNDVAPLSKLTAPLGVIAIPGNHEYYFDADQWIAEFKRLGMQVLV
NEHVILRKGADQLIVAGVTDEAAPAYGHKGPDLAEALAGAPKDVPTILLKHRPQGAPDSA
AASVGLQLSGHTHGGMITGLDLVAGYANQGFISGHYDVGKMRLYVSNGTALWNGFPIRLG
VPAEITEIVLRASPTLNEHPVRRTFL
>A0A5E7JDK7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MALNKFMSTFMGACLVASAITAQATTGMPKHMVFASDTQYPWTDKTDIREPESDSEFTAR
SKWLIETQLASIAEFRNLHGSQAQVPLMINGDITAFGHGWQRSFMKDSLNRHFKGEYLYG
LGNHDYENNVDDCFTNNCAAGSIVEFKEHHEGKVDNFDLKITDGFLSKTYAGSLAYSKNI
GEVHMVQLNNEPTYTTRIAHPLNPTTFEINDALDWLETDLRLARASGYAIIINMHKPLRH
QGSPEQKKRFHDMVNKYQVTAIFAGHLHTEGGSSYWEGSVPMYLSGSTSQQTYLTANFTE
DRKHLQIYLVKNNQWRERTLIDTTVVHSIFAQRP
>A0A5E6SUR5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MVFASDTQYPWTDKTDSGDFESGSEFETRSKWLVETQLASIADFRNHQGSQAQVPLMING
DITAFGHGWQRSFMKGMLDKHFKGEYLYGLGNHDYENNVDDCFSNSCAAGSIVEFKEHHE
GKVDNFDLKVTGGFLSRTYSGSLAYSKTIGEVHMVQLNNEPTYTTRISHPLNPTTFEIND
ALDWLETDLRLARVGGYAIIINMHKPFGDKVSPAQNKRFLDMISKYQVTAIFAGHLHRDG
GDAYWKGNVPMYLSGSTSQQTYLITSFTEDRKQLQIYLVKNNQWRDRTLIDTVEVHSIFA
RRP
>A0A4Q9D915|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Obesumbacterium proteus|TrEMBL
MESLFQLTVARGAPVRILQITDTHLFAGEHETLLGVNTYRSYHAVLEAIHAQSRPYDIVV
ATGDLAQDHSVAAYQHFAKGIATLNKTCLWLPGNHDFQPAMVDTLANAGVNPAKHMLLGD
HWQIILLDSQVFGVPHGELSEYQLEWLDRTLSLYPARHSLILLHHHPLPSGCTWLDQHSL
RNAHMLGEILQHHPLAKTLLCGHIHQDLDLEWQGRRLLATPSTCIQFKPLCTNFTIDTLS
PGWRYLDLHPDGTLTTELHRLEGTEFRPDLDSDGY
>G5LTS5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Alachua str. R6-377|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A6P7NKT8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Betta splendens|TrEMBL
MDPACGKAGTASLVAGGGTGVSAKAPKHLWRQQNQAALSPLHHHALVARKNDRVRQRGFS
DTERYLNPRNMDRTYAVDTGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSSGRSPLDPMAS
PGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLA
SLRTVRNNFGALTNIQQDRASNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQ
LETLQTRHSVSEMASNKVRVTKCLTLTGLDKTFNLQQFHL
>A0A5Y1Y748|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella diarizonae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAEISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLVLQANGVLETEVHRLQDTRFRPDTASEGY
>A0A395L928|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ensifer sp. M14|TrEMBL
MFKLAHISDVHLGPLPDLSLRELASKRITGFVNWHRNRRRHLFTGTLDCLMADIEKRDPD
HMAITGDLVNLASSREITAVTDWLEDAGDPANISIVPGNHDAYVPGAYEKTTRAWYPFMR
ADGAPVDWHESHRCFPYMRVRGPVALIGCSTAVATPPFAASGYFGQRQARATVNLLRQAG
DAGLFRVVMIHHPPIRGATSLHKRMLGIRRFAATISSGGAELVIHGHTHLNTVYSLKGPN
GPVPVVGISSASQGPGGHKPPAAYNLFTIVGEAGNWHLTRERYALNADATGATLVETTRF
>A0A2W0G6M3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae complex sp|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAEHRDCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
KWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLTKFPRVKHLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLAGAQFRPDTASEGY
>A0A8C5RC13|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Laticauda laticaudata|TrEMBL
LEELDWCLDQLETLQTRHSVSEMASNKFRRMLNRELTHLSETSRSGNQVSEYISNTFLDK
QHEVEIPTSVPKEKDKEKKKRPMSQISGVKKLMHSSSFSCAAIPRFGVKTDQEGLLAKEL
EDVNKWGLDIFKIAEYSGHRPLTVIMYSIFQERDLLKSFHIPADTFITFMMTLEDHYHAD
VAYHNNIHAADVAQSTHILLSMPALEAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTN
SELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQMLRKMAIDMVRSFVGHG
>A0A1W6KDI1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter salarius|TrEMBL
MTENDNQRALRVLQLTDPHLMADPAGGLLGVNTRDSLDAVIAQVFRDHGQPDLILATGDI
AQDASEEAYRLFGDKLEVFQCDTAWMAGNHDDSPLLSRIAAERGANQRHIIQGGWQFVLL
DTSVPGKVFGELSEPELAFLEKTLSENPDLPALVALHHHPVEIDTRWMSPIGLRNRDAFW
QVIDRFPQVKIVLWGHIHQELDQTRKSARLLATPSTCIQFTAGSVEFSVEDKAPGYRWFE
LLPSGEFSTEVSRATDFVFELDSNSTGY
>A0A6F9ZA30|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacteroidaceae bacterium|TrEMBL
MTNRLLFFVLMALSFSGCDMLETHPYDVHITGERELTNKNIQLIENKMQGKKTIRFAMIS
DTQRWYNSTEDVVKAINAHGDIDFVIHGGDQSDFGVTKEFVWMRDIFNKFQMPYVCLLGN
HDCLGTGEDAYRAIYGNPNFAFTAGNVRFICLNTNAMEYDYSEPVPDFNFIENELNNLPS
EVEKTVFAMHVKPFEFIFNNNVAKIFQLYVNQFPQVQFCLYGHEHQLTVDDLFDDGILYF
QCPCIDKRIYLLFTIKEDGTYDYETVEF
>A0A6P4EVD5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila rhopaloa|TrEMBL
MIISSQPNLVGSVTTTSTTTTTSAHMSEESVPSTCNCGAVGVSVGVGVGGALGARQSPPA
VEPTTTATPKTPTSTAPGRDSLTRPASESELNVGTGTSGTSSSGGGNSRPGHRKSSLALA
LTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLVFHKSDSICEAITAACQRHQLDVTLV
KSKEEALDTLQKSYATAQCYHLIIIDARSTKNLDAEHIARTIRHTHGHHLTTIIAVCKKS
FFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRL
KEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSDLSTISEQCKNIKEFDGI
LTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHS
VRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLE
FLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVP
AKMKSNPIIMELLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCK
AWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDMLVMDRMEEATALIAAAAHD
VDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSA
RSTIIDMILATEMTRHFEHLAKFVSVFGGEEPREHNCQTDEETSILMRRMLIKVADVSNP
ARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMM
HAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLAEIMAKQPPVGKMANSK
>A0A653KT27|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. 8I-beige|TrEMBL
MTLNNEKNWTIIQISDTHLMDQDHLEFVRMNPEQSFHHVMQHIVERHPQLNAIVHTGDLA
QVPVPRTYQRYLDFMQSLKTPFYQVPGNHDNVEHFPFHQQQNKVHVIHFGPWSVVLLNSA
VKGKIDGWVDEAQLKQLEQILQEFAQQHIVIACHHHPFEMQSKWIDQHKLKNTQDLTAVL
AKYHNVKIVLSGHVHQESWREWHGIQFYSTPSTSVQFKPLSDHFALDEQAPGYRILQLNA
DGSHETHVERVLHAQQKINVEISGY
>A0A8B3JL41|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. WCHEn090032|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDHVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLHADGTLTTEVCRLTGAKFRPDTASEGY
>A0A645AXJ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKDKGKLKFNENGTFQIMQLSDLHITKKNKNNKETLEFVVNAAQNLNPDLIVLSGDIING
NRLFGAPASDKSKVKKAIRNLMKVLDKLDIPVAICFGEKDDDNRIYKHTQAKFYHKYDCV
CVGESYADCGTYYLPVYSSDESEIKYCLWIFDSQYEDDTQKINAVTDNRLEWFRKMSDEL
KEKNGGSTVYSLLFQHTFVPEIYLNLTKVPSNTVGCIQKNDQFFIMNKDNTEGFLGEAPT
TCVQTGQLAEIKKMQNVVAMVFGNNHTNCFVSEYEDIDLIATPTASAFAYGDELRGLRML
TIYENDTEAYETSIYSYLDILGKNPRKK
>A0A644WQU0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MVRIALISDIHFGKDARTMEFSVPGESCGGNTEGAASLTDGLVDVLQSMNVEYIFVAGDL
TSVGSPQEFFYCEKKLIEIINRVNIPIDNLIVGVGNHDIDWKIAKLSEGYQNGASEETVQ
IVKNGYDRIAGNASLYNLNSIGAQRYLNERGDIPFTGVIEREDFILFILNSGWCCTPEKL
GGMLTQQQVEWFREQASRYRDDQRWKIVMLHHHPRAYENPIKTKNKENISLLEEGAELIN
IAGEYHIDLILHGHRHHPRAETMCVGDWDYPVAFICAGSLSVSPIDRNGGDIPNTLHIIE
LADNPRAIYLYNYEYSSGSGWIRSTNFRQDNPMDYIMLLGCSFRIEERRRAIIELAATHG
SNEIVWAELDDCLKSLSAEKLLKMMIETLADTHRVTGEFFRNPVYILDKKLL
>A0A4P9D7D6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. E4742|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADSRFQPDTASEGY
>A0A7Y7XCV3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas gingeri|TrEMBL
MPSVSTQSTPADSVLLVQLSDSHLFAEAEGTLLGMNTRNSLQRVIDCVLAEQPDVDLLLA
TGDLSQDGTVASYLQFREMSAAIDAPARWLPGNHDELREMAEAARHSDLLEAVVDIGNWR
IVLLDSAVPGSVPGYLQDEQLQLLAQSLSEAPQRHHLVCFHHHPISIDCAWMEPIGLRNP
EALFAVLDRFPQVRALLWGHIHQELDRERQGVRLLASPSTCVQFAPGTEDFTVDDKAPGY
RWLRLHSDGRLETAVSRVHGFDFEVDYGGTGY
>A0A834J6A5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vespula vulgaris|TrEMBL
MNIPRRSTQPILYVCGSTEDYNNNSNNKSYPWYSSFFDAICGGMSSKWSVHKAKTQMHDL
STLSKNSSIPITIKKIEMKDLQVKRKKVNEPLNTPRTRRRASIYEQLKSQYLDKEFIGKG
PQDIDSHLLTSSAPELIKILLVFSKDDQQMEILANISRRLGWSVSVAKDAEKAVEIFQTR
GHELVIIDHRGQRAVEGDAICRAIKSSPVYHSSVIIALVKKSYFMNSEKDEIVTLDLLEK
GFSRALLECSNEGILINELVGIYTSSVLPKTQLAAAHALYLALDRCHDMVHITNERNILQ
FLNKVTEKLLGYKTEELVGRNLGEIVHYENFALIEQQLSKGREFEGNMNCKRKNNQMITI
NCRIIPFCITPKKATHYIYVYDTLYLLENSGPLSPINSPLQSTQRTSILSNRKSSDVKSA
LSEGHRRYSLQKLHSLQLEAPITKVITLLSNAITETTNPETAGQIDKAIEILKTTELYVP
HLRDDKIYTDPVATDLVGALLSASRNPWDSRRSSADSTRLSHLRGISITSTRGPAKPFRG
PQEIMELLDNSLEWSFDIFKLEILTEKRPLVFLGMNIMNMYDVPNKLDCDEKVIHNWLTL
IEANYISTNSYHNSTHAADVMQAIARFMQSDRLKQILDPLDEVAALIAAATHDIDHPGRS
SQFLSNSNNRLAILYNDLSILESHHAALTFKLSLSDDKVNIFKNLDRDTYKILRTNIIDM
ILATEMTKHFEHLARFMNVCSLRIGEDQPMEYNTENVDVTILLQPDNVMMVKRMMIKCAD
VSNPTRPLRSCIEWARRIAEEYFNQTDEEKKLNIPVVMPMFDRMTCSIPKSQIGFVDFII
NDMIEAWDSFIDMPEMLNYMRHNYDKWKEFNDQGITTLQDIEKIQLQPDLKIIKLSEERR
>A0A2K9QA97|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dickeya zeae|TrEMBL
MESLLTLPVASGARVRILQITDTHLFADEQGTLLGVNTNRSYQAVLNAIAAQQMNVDLIT
ATGDLAQDHTQDAYTHFATGIRRLGAPCVWLPGNHDFQPAMVDVLARSGIAPSKHVLLGE
HWQVILLDSQVFGVPHGELSEYQLEWLDRSLQSQPERHTLLMLHHHPLSSGCTWLDQHSL
RNAHSLDALLSRFPRVRTVLCGHIHQEMDLDWNGRRLLATPSTCVQFKPHCTNFTIDNVA
PGWRYLELLPDGGVETRVCRLEGNEFLPDMDSEGY
>A0A6H1S225|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dickeya zeae|TrEMBL
MESLLTLPVASGARVRILQITDTHLFADEQGTLLGVNTNRSYQAVLNAIAAQQMNVDLIT
ATGDLAQDHTQDAYTHFATGIRRLGAPCVWLPGNHDFQPAMVDVLARSGIAPSKHVLLGE
HWQVILLDSQVFGVPHGELSEYQLEWLDRSLQSQPERHTLLMLHHHPLSSGCTWLDQHSL
RNAHSLDALLSRFPRVRTVLCGHIHQEMDLDWNGRRLLATPSTCVQFKPHCTNFTIDNVA
PGWRYLELLPDGGVETRVCRLEGNEFLPDMDSDGY
>L1M0G0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida CSV86|TrEMBL
MPHATLSSSAPVRLVQLSDSHLFADGEGSLLGMNTRDSLQRVIDQVLTEQPRIDLVLATG
DLSQDGSEASYRQFREMTAVLGAPTRWLAGNHDEPLPMERVAAGTDLLEAVTDIGKWRVI
MLDSSIPGSVPGRLEADQLQLLDQALGSADGRHCLVCLHHQPISIDCAWMAPIGLRNPEA
LFAAIAPYPQVRALLWGHIHQEWDQHLDGRRLLASPSTCIQFEPRSEDFKVDEQRTPGYR
WLALHDDGRLETGVSRLGDFAFDLDYGNGY
>A0A1X1PEX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Burkholderia puraquae|TrEMBL
MLLAQISDLHIKRPGQLAYRRVDTAAALARCVAKLNALVPRPDAVLVTGDLTDFGHDEEY
GNLRGLLAALEIPYYLMIGNHDDRAGLRRAFADRAELQDGEFVQYALDVGAVRVLALDSQ
VPGASYGDLCDARLAWLAAQLDAARDRPVIVALHHPPFAAGIGHMDKLRLAPAAAAKLDA
LLRGHPNVERVLCGHVHRTMFTRFGGTLASAVPSPAHQVAFDLRTDGPSAFRLEPPAFAV
HRYAPDTGMTSHHVYVDEGAGPYPFYEPTGELVD
>A0A1S0ZBV0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Saintpaul|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>B1G8Z1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia graminis (strain ATCC 700544 / DSM 17151 / LMG 18924 / NCIMB 13744 / C4D1M)|TrEMBL
MKIRVLSDLHLENDEPELIPHAEADLIVLAGDIHNHAAGPRWAAQTFDGATPVIYVPGNH
EYYDGEFGALETALYDAAAQVDNVYVLNNAALVDPQGRWRVLGTTLWTDFALFGADSAAL
EESMEASRRAMLDFRGPIQINWPHGLENRAEDDARDFTPGDALALHRQARAWLENELAKP
FAGQTVVVTHHAPHRLSLAERYAEDHVSAGFVNHLPELVRAPVTLWIHGHTHTSFDYTVN
GTRVVCNPRGYFERRSRQWENPQFAWDKVVEI
>A0A3V2FRI8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Braenderup|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A8G6XPR6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas aeruginosa|TrEMBL
MSRHSNTPATDASVLLVQLSDSHLFAEDGARLLGMDTAHSLEKVVERVAREQPRIDLILA
TGDVSQDGSLDSYTRFRRLSAPLDAPLRWFAGNHDEREPMQRATEGSDLLEQVVDVGNWR
VVLLDSSIPGAVPGYLEEDQLELLRCAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGY
RWLRLHDDGRLETGISRVDDVVFEVDYDTAGY
>A0A6J2XMC2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sitophilus oryzae|TrEMBL
MIIQNKNSSEEIDDMDSLIDNEIVEEEEGEEEESRNEVLMEDIVNDIGRGVLHHRKSSLA
LTPEEEPFDINRGPNELKYGLIIPNIKHQLKLLLVFAQLDPVSETFTKAAEKLGFEVTLC
HTDISALEEYQTKSHDLVIVDNRITKAFDNDLLCRSIRNTRGSQHTVMIAVVKKSAFERD
DITITSLLESGFNRCLIETTNLLTCVNEMILLKHSDIRIMAQHATCQALYTALDKCKDLV
IVTDDTYKFQYMNTACERQLGLRQEDTLGKTLQEQLVYDTVQINTMGSSLLRAREWSGPM
TLKRKSTQDPIVTSCKAVPFSCAGRMPTHFILVFDTNSIDPNMLSQSRGSIHSIRRGSTD
VRSVGSDYLRRTSLAKLNALPLEAPITKVIGLIDQIRESLGSNPQAIQLIDRVEDILKSS
ELYVSHVKEDSKVKADEPVVSDLITALLSKTPQPTLSASSRRSSNDSSVFRPSRTGLIKA
PAAIRDLLETSLTWEFDIFKLEDLSRRRPLQHLGMNLFNHFDVCGSLNCDEKTLSNWLTV
IEANYHIENSYHNSSHAADVMQATAGFLEKERMKSIMEPLDEATSLIAAAAHDLDHPGKS
SAFLSNSNNPLAILYNDVTVLESHHSALMFKLTLGDERVNIFKNLDRDTYKLARHNVIDM
ILATEMTKHFEHLAKFVNVFCPRSSIGSDMDQPDDYNALLSPENTTLVKRMMIKCADVSN
PTRPLRICVEWARRIAEEYFQQTDDEKMRGLPVVMPMFDRATCSIPKSQIGFVDYIINDM
FEAWNAFIDMPELLTYMRQNYIRWKEFDEQGHTTLSDIQKLQATVLSPSVSSAIKSD
>A0A6P4I6Y0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila kikkawai|TrEMBL
MGCSPSTLPAPNAAGGGGVGGAPGGQGSLPLDATEKDGSRLFCIKLRRSRLRRCSCGGVT
LQVPNDGNGSTAGSGTGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHS
VVRRATGSTGTSGTSSSGGGNSHRHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPN
PQLKALLVFHKADSICEAVTAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDA
RSAKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLA
MCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLNMR
LDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAP
THLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSL
PLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIG
ALLTVGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKANPIIMELLEESLSWDFDIFKL
EEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVMEAHYRKSNTYHNSTHAADVM
QATGAFITQLTNKDMLVMDRMDEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLT
VLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSV
FGGEEPREQHSQTEEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEK
QRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKY
DEQGVNTLADIMAKQPPVGKMANSK
>A0A101S5Z8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces griseorubiginosus|TrEMBL
MTSTAGAAAQLLAISDLHIGYPENRALVEELRPGTDDDWLLVAGDVAETVADVRWALETL
AGRFRQVVWAPGNHELWTHPKDTVTLRGVARYEHLVAMCRDLGVLTPEDPYPVWEGPGGP
VAVAPLFLLYDYSFLPAGCTTKEQGLEYAHGTGIVCNDEYLLHPDPYPTREAWCRARVAE
TERRLDALPDDLPTVLVNHYPLDRHPTDVLWYPEFAMWCGTTLTADWHRRFRVETMVYGH
LHIPRTTWHEGVRFEEVSVGYPREWRKRPEPPGRPRRIVPGEVGAR
>A0A1R0FTS7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter braakii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRAKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A3T2UUG9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella flexneri|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A496XFX0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MHQSPHMTHFIEVSGDVVQVVQLTDTHLCQAKGGTLLGMDTDQSLQAVIDLVQDERPAVD
LLLGTGDMSDRGAREAYERLQGYFAQFPCENFWLPGNHDDRNAMEAVANTATRLCKEIRV
SRWQILMLDTQVPGEVGGELGQAELALLEQALQSARDEGLYTLVCLHHQPVAIGCTWLDE
QMVADAAAFFDVLDRYPGVRGVLWGHVHQQIDRQRKGVSLMASPSTCVQFAPGCVNFKAD
NMQPGYRWLDLHGDGRIETAVSRLRGTQFTVEPDAGGYL
>A0A0M7EBS8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQEAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPARHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLAKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLAGAQFRPDTASEGY
>A0A5X3G0Y1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Kentucky|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPHVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A8E8KU20|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQFSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>C3SUD2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A812F9N3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. B1FIG11|TrEMBL
MQSSSDSIKLLQITDTHLFEADEGSLLSVRTADSFAAVVQEILNHQVQYEYILATGDISQ
DHSAESYQRFAEGIAPLKKDCFWLPGNHDYKPNMGSVLPSPQIQAAEHVILGEHWQLVLL
DSQVVGVPHGRLSDQQLALLEEKLAENPQRHTLVLLHHHPLLVGSAWLDQHALKDADAFW
QVVDRFENVKGILCGHVHQDMNVLYNGIRVMATPSTCVQFKPDSDDFALDTESPGWRELE
LHSNGDITTEVNRLPDGQFQPDFNSNGY
>A0A3V7I4W1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Weltevreden|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A0K4QQH7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYLHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCCWLDQHSL
RNAGELDNVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A718ZMW2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella typhimurium (strain SL1344)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A2X3EGK3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kluyvera cryocrescens|TrEMBL
MESLLNLPLAGGASVRVLQITDTHLFAQKDETLLGVNTWESYHAVLQAIHASARDVDLVV
ATGDLAQDHSSAAYQHFADGIASFSAPCVWLPGNHDFQPSMYSTLQEAGISPAKRVMIGE
RWQILLLDSQVFGVPHGELSDFQLEWLEKRLAEAPERHTLLLLHHHPLPSGCSWLDQHSL
RNAGALDGVLARYPRVKNLLCGHIHQEMDVDWNGRRIMATPSTCVQFKPHCSNFTLDTVS
PGWRWLELHDDGSLTTEVCRLAGVKFHPDTASEGY
>A0A8D4TUQ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGKH
WQAVLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLSPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAEFLPNMQEEGY
>A0A2X0RCV1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lactobacillus helveticus|TrEMBL
MKGKLFRKCKKTSQGKDLYYQETALTAFMRMAQRKKPAAIIVTGDITFNGERVSAEKFAE
IFKPLKHTQVLVLPGNHDIFDGWAREFRGKKQFYAGEISPMFWRSIFAKSYRQAFNTDDS
SLAYSVQLNPQYFLILADSNIYGTEETTAAPHTRGMIGKSQLKWIEKQLQYAEKINFVRF
YLCIIICMLIILL
>A0A762B0V6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
LWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5J2ECI8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Rissen|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRENGVLETEVHRLQDTRFRPDTASEGY
>A0A8E6JJF3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Typhimurium str. CFSAN000648|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5C5DBR3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Buttiauxella sp. B2|TrEMBL
MESLLNLPVAGGGQIRILQITDTHLFSGKNETLLGINTWMSYQAVIDAILAEQRHYDLIV
ATGDLAQDHSVQAYQHFVEGIAEIPAPCVWLPGNHDFQPAMFSSLLEAGISPAKQVFLGE
NWQILMLDSQVFGVPHGELSDYQLDWLERKLAATSERHTLLLLHHHPVPAGCSWLDQHSL
RNAQELDNVLQKFPKVKTLVCGHIHQELDLDWNGRRMLATPSTCVQFKPHCANFTLDTIE
PGWRWLELGPNGEVTTEVCRLKGAVFNPDTASEGY
>A0A3B5L8M9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xiphophorus couchianus|TrEMBL
MDRTYAVDTGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSSGRSPLDPMASPGSGLILQAN
FVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFG
ALTNLQQDRASNKRSPMCNPPPITKTTFTGKKFKQEM
>A0A370R1K0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacillus tribolii|TrEMBL
MLYAGRTSEHDQSHEGHYLESLFHLTVASGAPVRILQITDTHLFAGEHETLLGVNTYRSY
HAVLDAVRDQNRPFDLIAATGDLAQDHSVAAYEHFAAGMARFSQPCIWLPGNHDFQPAMV
DTLAEAGINPTKHVLLGDSWQVILLDSQVFGVPHGELSDYQLEWLDAALAKHPERYTLTL
LHHHPLPSGCTWLDQHSLRNAHMLGEILSHYPRARTLLCGHIHQDLDLMWNDCRILASPS
TCIQFKPLCTNFTIDTVAPGWRYLDLHPDGSVTTELHRLTGTEFRPDLDSDGY
>A0A730ZIG0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. houtenae serovar 1,40:z4,z32:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A8B6KWR0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia enterocolitica subsp. enterocolitica|TrEMBL
MESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFASGISRLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLVGE
NWQILLLDSQVFGVPYGELSEYQLEWMERCLMAHPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PRWRYLDLLPDGRLETEVRRLASDEFCPDMDSDGY
>A0A4S2PPX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rodentibacter pneumotropicus|TrEMBL
MKNTFVYRAEKPMVKLLQITDPHLFKDEKNELLGVNTQASFAQVLKEIQQEKREFDAILA
TGDLVQDSSDEGYQRFVNMVKPFGLPVFWIPGNHDFQPKMVENLNQSPMEKAKHILLGEY
WQVLLLDSQVYGVPHGELSQYQLDLLKTTLEKYPEYHTLIVFHHHVLPTNSAWLDQHNLR
NSHDLFDVLSLFKNVKGILYGHIHQQVDSLWQGYQVMATPSTCIQFKADSQHFALDKAQP
GWREIELHSDGTIVTAVKRIRQAVFLPNMQEEGY
>A0A7M1NUW8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus parainfluenzae|TrEMBL
MNNRFEYEPASEIVKLLQITDPHLFKDTSKELLGINTHESFSQVLKEIQLESFEYDVVLA
TGDLVQDSSDEGYLRFVEMVKPLNKSVFWLPGNHDFQPKMAEHLSQSPINASKHLLLGKH
WQVILLDSQVSGVPHGELSAYQLDWLKTKLAENPARHSLVVLHHHLLPTNSAWLDQHNLR
NAHSFSAVLAQFNNVKGILYGHIHQQVDGYWQGYQTMATPATCIQFKPDSNHFALDTLQP
GWREIELHPDGRIETRVKRIKQKTFLPNMEEEGY
>A0A0E2L2C4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli (strain UMEA 3162-1)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A1W4UA69|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila ficusphila|TrEMBL
MGCSPSTLPAPSASASAAGGQSAERGSLPLDASEKDESRLFCIKLRRSRLRRCSCGGVTL
QPPSDGNGSTTGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHSVVRRA
TGSTGTSGTSSSGGGNSRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLK
ALLVFHKSDSICEAVTAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSTK
NLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSV
ELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEI
ISKQLEDIFVSDLSTISEQCKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLI
FNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEA
PITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLT
GPSVYSSRRSSNDSIIRTGSSTRTASIVPAKMKSNPIIMELLDESLSWDFDIFKLEEITD
YHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGA
FITQLTNKDMMMMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENH
HAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEE
PRDHNSQTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLP
IVMPMFDRATCSIPKSQIGFIEYIIQDMIHAWESFIDMPQLITYMQINYSQWKKYDEQGV
NTLAEIMAKQPPVGKMANSK
>A0A2M4A8P1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles triannulatus|TrEMBL
EEPLDSCPRLVSDLKFPNLLPPNPAIKILIAFCKNDPVFEALVNASHRLSFEPTFVKSAE
AAIDAFQNPTAGGHHIIIVDARYPRIIEAEALGRSIRNSKGSQHTTMVAVVKKSVFEKDD
TAVISLLDVGYNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQALYTALHRSREAVI
ITDDTLRAQYANRASERVLNMKLDEIVGRSLGDLVTADISNILSHTSRYKDYDGYLTTRR
KSQESSQIHVRAVPVSCIGRNPTHLVLILESSASALASISAAGEALQTLPQGKEVARGSL
HSIRRPSFDVRSIASDGLRRTSLVKLSSLPLEAPITKVLSLLAQVQENCSLEEAKLLDRV
MEFLKREGLYSPQMKEIRPEDPVATDLIGALLTQGPTNILSSRRSSNDSIIRGGGRPSTG
SIVFNKTKESSQLSDLLHTALDWDFEIFKLEELTDKRPLVCLGLELFRRFDVYNTFNCDE
MTFKLWLIEMEKNYHSENTYHNSTHAADVMQATAVYLQQLSNRELKIMDRMDEATALIAA
ATHDIDHPGRSSAFLCNSDDMLAVLYNDICVLESHHAATTFRLTLADDKINIFKHLDRDS
YKLARSIIVDMILATEMTRHFEHLAKFVSVFGTDVESKEPLPPDNDDNQILVRRMLIKCA
DVSNPTRPLRFCVEWARRIAEEYFMQTDEEKRKALPIVMPMFDRTTCSISKSQIGFIEYI
IHDMMDAWNSFIEMPEIVRYMEFNYSQWKLFEEQGINTLSDIKRKQLSLAEEPSSIISLE
EKF
>A0A401RPT6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chiloscyllium punctatum|TrEMBL
MCVWVSLDCEELHLSVGLHFSNALVASLFDILKNGSTFNKSCCCIFPRLVCHPSVAPTSF
DVENGPSPGRSPLDSQASPGLVLHPTFPQSQRRESFLYRSDSDYDMSPKTMSRNSSVTSE
VHTEDLIVTPFAQILASLRSVRNNFTVLANTQGPPNKRSPAGPQPALCTLSDETYQQLAK
ETLEELDWCLDQLETIQTYRSVSEMASNK
>A0A2T0BGF3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clostridium vincentii|TrEMBL
MKIQIKNKLISLIIAKVSKVVEKSNVFIHLMDSNQFVSLHRRKNLRFVVVSDIHIAPNKC
LEKRKLKNVFSTMYNLDSNMDAIAIVGDLTDGGSEKEYNAFKRILDKNKKEETILIASMG
NHEQNTPSKFSSVTGRNPRENITINGYHFITVSPRLSEDTYGGSRYNLDEIWMKEQLEHA
ILEDGDKPIFVFIHHGIKNTAYGTDQWYTEDFEKIFNNYPQVIQFSGHSHYPLNNPKSIY
QKAFTSINTSTTSYFELETGMMYGTIPPKANRACQMMVIEVAGAAVQIRKLDLSSGEYIG
KDWIINTAEGKNKFKYVESRAQKSIAPYFEENAKVIINKIKSDSCVVTLNQAKVNDRADE
WLDDIVHSYKFDFIDKKTGEIFDSFKVWSEFYILPREDCLVQQFNQLKADTDYVIVVMAY
NAYGKVSTNQVRSSFKTKHL
>A0A2T3IRD8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium lutimaris|TrEMBL
MQTFTLPQTSRDSVVLLQITDTHLFADDGGSLLGVATKDSFHAVLDAVDTAARPFDAIVA
TGDISQDHTEHSYQRFCDGIARWSQPCFWLPGNHDYQPSMKAVLPSAQIKPCHQVLAGEY
WQVILLDSQVQGVPHGELSLAQLEMLELALSAQPERHALVLLHHHPLPAGSTWLDQHQLH
NSEPFWQVIGRYPQVKTVLCGHIHQELDRIQQGVRVLATPSTCIQFQPDSHDFALDQKGP
GWRYLILHSDGQLDTQVCRLEGHDFTPNFESAGY
>A0A8B2UDR4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. 9-2|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYNALQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDHVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLTGAKFRPDTASEGY
>A0A6S7CGQ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter piechaudii|TrEMBL
MPRVHSLARRHDAPAMLVQLTDSHLFGEPDTSMLGVNTDASLRAVLRQIEADGKRPDLLL
ATGDLSQDGEAAAYRRFAAILGQAGVLSGAQIRCLPGNHDLPAVMRQELPQWSAPVTDVG
AWRVVTLDTTVPGSNAGHLPDSQLDMLEAALADAPGRHTLIAMHHNPMQIDSHWHDSMMI
DNPQALFKRLTRWPQARVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNLA
PGYRWIKLYQDGSMATGVRRVQDALWHTALAPVNEQAA
>A0A8B7LW88|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila elegans|TrEMBL
MRNCLPKFSKVFRRKSSSAKSSSASAGQENRSNDPDSDTEPYGIAVRPAAISISHQPGDN
RNERPLADDDSSRSRLISSAHLDFELDLALDLALESALHSEPPAMATNGGIRPKSEGSCP
EMKVETISAASPAPGASPGPVAISLPFVARNSSKTPEEMELEYEANAEAESRDIMTPLRR
NTRPLSVAFAGGGSVGGGRNALQPEIVEVIRSMDVPAMLLNNLSLEGVRDSMEGDRAGSH
PVAELSPGHDHEDSVVLRRKVNCLERKAHSLYERRLPKVPKLHLLVAGKKPTEEEEFRTF
QRNLMDLKYPTVLPPNPPLKALLVFHKSDSICEAITAACQRHQLDVTLVKSKEEALDTLQ
KSYATAQCYHLIIIDARSTKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIAL
LDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLL
RIQYANRATERLLNMRLDEIISKQLEDIFVSDLSTISEQCKNIKEFDGILTVRRKSQEGI
PMHVRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSI
ASDGLRRTSLAKLTSLPLEAPITKENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDP
IATDLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKSNPIIMELLDESLSWD
FDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNST
HAADVMQATGAFITQLTNKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAV
LYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHL
AKFVSVFGGEEPREHNSQTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFM
QTDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINY
SQWKKYDEQGVNTLAEIMAKQPPVGKMANSK
>A0A0H3Q1M4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cholerae B33|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFAAEDGSLLSVNTADSFAAVVAAIGEEQVEFDAILATG
DISQDHTPESYQRFVRGIQPLKKACYWLPGNHDYKPSMHSVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEYPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRIHLGARVMATPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A366WE47|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter sp. F3R11|TrEMBL
MTSKVTARPFRVLQLTDPHLMISADGALLGVNTRDSLDAVIAEVLKSHGQPDLILATGDI
AQDATEEAYHVFGDRLGAFTAGSAWIAGNHDHAGRLAKVAAFYGSDRRHIVEGGWQFILL
NSSVPGEVFGNLAESELEFLAEMLEQHPDLPTLVALHHHPVDISAEWMRDIGLRNREDFW
QVIDRFPQVKMVLWGHIHQTHERQRNGVQLLATPSTCIQFTSGSRKFSVEDLAPGYRWFE
LEASGNFTTEVCRAMDFKFELDQNSSGY
>A0A2T3MJJ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium iliopiscarium|TrEMBL
MQTYSLPQTNPESVVLLQITDTHLFANGSGSLLGVATKDSFHAVLAGVDIAARHFDAIVA
TGDISQDHTPYSYQRFADGISRWSQPCFWLPGNHDFQPTMQSILPSEQIKPQQQVLVGEY
WQMILLDSQVQGVPHGELSTAQLALLEAALTRYPERHALILLHHHPLEAGSAWLDQHQLH
NNSALWHVIDRHPQVKAVLCGHIHQDLDRTYHGVRVLATPSTCIQFMPDSDDFALDHNNP
GWRYLELTKEGRIMTSVHRISGDQFKPKLDAEGY
>A0A5J4RUX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MHFAKEHPELKFLLTEIGCGIAGFTVEEIAPLFKPAISENIENVYLPERFLNKIMNILFF
SDTHCLHRRLKDIPPADMIIHAGDVSFSGEDHEVEDFIRWFGKLDYKYKIFIAGNHDFYF
EDETIRRIQRMLPENAYYLCDSGVEIEGIKFWGSPINPRFLDWAFNCERGEQIRGHWKLI
PKDTDILITHSPPFGLLDQTTRGVHTGCEDLLKAIKRIKPRYHLFGHIHEAYGMIQSGKT
TFINGSVLNEHYVIQNPPVAFCYENGFMQ
>A0A2H5W2X0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR10|TrEMBL
MWPLKWKTREREYRRQREEFFEAVKRLNRREFMKIAGLSAAVFTAKQIVPPHSFQVVDVV
RADPQEKPLFRFAYISDTHLYERELNERFVNAALRAVRDVNALDPPPDFVLFGGDLAQLG
QPKELELGKQILSELKVPVKMMVGEHDWFLDMGEKWRELFGPENYSFDHKGVHFIVLMSV
NEKDFWTERKMTPMERMLTVAQLDNPIQSRFEVGEEGREWLRRDLARVSKDTPIIIFSHS
PLYKYYRPWNFWTEDAEAIHEMLFPFRSVTVIHGHTHQLLTHRIQNIHFHGMLSTAWPWP
YAPEGLPKLTLPMERPDPFDEADGTGWGTVDVHRDGYVDKHYNLWSRNPITVAKAYLESW
GKEAIPPAPEFPPY
>A0A1B6GW39|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cuerna arida|TrEMBL
MGCTPSTHKKRGSRDDQSAHAHQLINSSGGSLRGVRGKRGSDGIIYHRSSGGDAGDSSGV
RRVWEWCVAASRCTLRRRAADAALVSTDDHDAQINELNADQTIEQQCHRLHQLNIPVPRP
QPIRVLLVFAKDDSTCNTLANAAEHLGLQRDIASTLDQALEFYQGQSSWPQIIFIDMRFS
WFKGDQICRSLRAVKRTHHIIFVGVCKKSAAEKDEKELRALLKIGINRVVVEPVSVVQAV
SELVQLAQGQVALHALLAQNEAIYLALDKSRDLVLVTDHSHIIQYVNRTWCQVFGYKVEE
LLAHSLPYFHQLGNMDQVTRQLERGFDWEGKISWRSKSGENITLQCRAMPYQAVGREPTH
YVYVQDNPLENHIYPRGSVPSIRKGSYDLKSINSEGAQSARRQSLAKLHNLPLEAPITRV
ISLICAAQENSTGQVVQILDKVVDILRTTELYSSHLKADNLRCEDPVTSDLIGALITQGP
VPVSTTRRSSNDSAAVKAAQALPPGAKAVFAMNASPQIKELLDSSLLWDFNIFRLEDLTG
KRPLVFLGMNLLLHFEVHKTLGCDEKTLYNWLTVIERHYHVTNTYHNSTHAADVLQSTAC
FLERERIKRLLDELDEACCLIAAACHDIDHPGKSSAFLANSSNELAILYNDVSVLESHHA
ALTFKLTLRDDRVNIFKGLERDTYKVARQSIIDMILATEMTKHFEHLAKFVSVFNKPNST
SDDGSGDAKSPSDCGGEFALTSSADEINLVRRMMIKCADVSNPTRPLKMCVEWARRIAEE
YFSQTDEEKANHLPVVMPMFDRTTCSIPKSQMGFVDFIINDMFEAWDAFIDMPEMLYHLR
SNYQYWKDLEEKGVTSLGDVTLKQSSSSSPNPNLPNIPEKSF
>A0A448TW19|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinobacillus delphinicola|TrEMBL
MSDAYQHNIDSDAVKFIQITDPHLFEDESSALLGMNTSDSFSQVLKEVVADTFPYECVLA
TGDLVQDRAKKSYERFCQQIKSLNKPIFWTTGNHDYLPDMHEVLGQYPDYIFPHKHILMG
KHWQVLLLDSQVYGVPYGRLSPCQLAWLDQKLYQNPERYTLVVFHHHIISTDSAWLDQHN
LRNVYDLLTILKKYPNVKGILGGHIHQSMDKMWEGYRVMSTPSTCIQFKPANHKFKLDEL
QPGWREVTLHANGDIETQVKRVQQKTFLPNLLGEGY
>A0A379ESI6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurella canis|TrEMBL
MFSTYTYETSAEVFKFVQITDPHLFKDEKSELLGVNTLQSFNQVLEEIKESGFHYDFVLA
TGDLVQDSSNEGYVHFCEQVKKLEKTVFWIPGNHDFQPKMFEILNQHQDNLNAKKHILLG
KHWQILMLDSQVFGVPHGELSQYQIDWLLAKLKDHPDRYSLIVLHHHILPTNSAWLDQHN
LRNAHDLADVLAPFSHVKGILYGHIHQEMEGEWKGYKVMATPSTCIQFKPDHHTFTLDCV
QPGWREVELHPDGRIETRVKRIQKVQFFPNMHEEGY
>A0A6I4Q8C8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gilliamella sp. Pra-s60|TrEMBL
MESFLKLPIRNRNYGRILHITDTHLFSDDDSSLLGVHSNASFLSVINEIERSNKKFDLIV
ASGDFVQDGSKKAYARFAKQINKFNTPCVWLAGNHDNYAYMQDVFDNYQLADNKIVQLGS
KWLIVLLNSQVEGQAYGFLPESELEFLQNALTKYSSRYVLAFLHHHPISSGCHWLDQHIL
KNSGQLEQIIQQHPNIKGIGWGHIHQKQDYIWHHCNAFSTPSTCFQFKPECYDFQLSSDD
APGWREIKLNADGSIESDVYRLTNNQFLPDISQNGY
>A0A090S3F0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio maritimus|TrEMBL
MKTTPSDESQLSSVRLLQLTDTHLFAPHDGCLLSVNTQDSFHAVVAEVIQQGTQFEALLA
TGDISQDHTEASYQKFVAGIEPLGLPCYWLPGNHDYKPCMNSVVSTPLIQDVTHALLGEH
WQVLLLDSQVVGVPHGRLSDSQLDFLERKLTEHANRHTLVLLHHHPLLVNSAWLDQHSLK
DAHEFWQVVDKHDNVRAVLCGHIHQEMDVIREGVRVLATPSTCVQFKPNSNEFALDTRAP
GWRELELCADGTVNTEVKRLPHGSFRPDFNAEGY
>A0A091Q398|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Leptosomus discolor|TrEMBL
VTHSMCFVHSFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDL
SPKTMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLL
>A0A7C2P673|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MRMAFASRRREGRAPAVGLSLRSAIAFAGLNSRLWPGGRPRRLERGVEDERKLSPSAYRP
RNFAQPAICEGIPATVSVFAYDRTPMTPSGGGRFMARKNLSLKLLQISDTHLHAAADSRM
RGVTTYATFLAVLEHAQRDPRWPVDAIIATGDIVQDESRAGYERFRAALEPLGVPVYSIP
GNHDDPKLMGEILASGAFHVGGELRQGEWSVVLLSTFLAGEDAGGLGPARLSGLKQALAA
HAGQNVLIAMHHHPLPMGSTWLDGVALRDAQAFWSIVDAHSNVRAVVCGHVHQAGDRMRN
DVRFLSTPSTCAQFLPGNEFFALDDRPPGMRWIELYDDGRIETEVTWLPAAART
>A0A6J3KGV9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bombus vosnesenskii|TrEMBL
MGCKTSMLECIEDTGEAEKRKHSDMVNQGSLLGKTEYDVLRRRSSFEDVAVDDDENADCS
ALKGPQNIEAHPLTNSVPSLIKILLVFPKDDQQMDVLATTSRRLGWSVSVAKDAEKAVEF
FQNRGHELVIIDHRGQRAAEADTICRYGELFFKNQPNSSGVRLYILINTIYFRAIRSSPA
YHNSIIIALVKKSFLMHGEKDKIVTLDLLETGFSRALMECSHERLLINELVGIYASALLP
RTQLAAANALYVALDRCRDMVHVTNDKHIVQFVNKISEKLLGYKTSEILGKSIADIVVYD
NFVLMEQHISKGREFEGNMNCKRKNNQMITISCRVIPFSINLKKPTHYIYIYDTTYLSEN
IGSLSPTPSQSVYSRGNMIVSQRRTSDMKSSEGRRRSSAHKLHSLQLDAPITKVISLLSN
AITESTTPDTAAQIEKAIDILKTTELYVPSLREDTDPVTTDLVGALLASPRKAWESRRSS
VESTRVSMSKTFSTTTASRMQIKSFRGPQEIAEILERCLEWNFDIFKLEILTEKRPLLFL
GTTIMNMYRVPARLGCEEKVVQNWLTVIEMNYQSRNSYHNSTHAADVLQATARFMQSERL
QQILEPLDEVATLVAAAAHDVDHPGRSSQFLCNSDNKLAILYNDLSVLESHHAALTFKLS
LSDDNVNIFKNLERDTYKQLRQTVIDMILATEMTKHFEHLAKFMNICSARMMDSPQLDDY
TDTVDMSVVLQPENVVLVKRMMIKCADVSNPTRPLKCCVEWARRIAEEYFNQTDEEKRMQ
LPVLMPMFDRATCSIPKAQIGFVDFIINDMVEAWDAFIDMPEMVGYMRQNYEKWKEYNPK
KMKDTVIESYF
>A0A7V8V9V0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bremerella alba|TrEMBL
MKSILVAQSFVWIGVILLGGVSAQEKPVSDTPNLVHDRHMHHHNHHHETEQPTEKRFFTT
RSSQVMLPLPNEQDAFVFAVFGDRTGGPKEGVNVLADAVRDVNLIEPDLVMTVGDLINGY
NSTEQWLGQMREFKAIMKELLCPWFPVAGNHDVYWRPLDDPKMPEGQHDQHYEMHFGPLW
YSFQHKKCNFIVIYSDEGDPETGEKNFRNAKAQKISDEQLAFLKQALQRGEKDDHQFIFL
HHPRWLGGNYGNDWKERVHPLLKEAGNVTAVFAGHIHYMRYDPQDGIEYVTLATVGGGQS
SKVPEAGYLHQYHLVTVRPKQVAMAAFPVGEAMDVREITAQLQQQAVKLANQKPKVSTKL
APAGDDLQEGTVTTVIENPTDYPIDFTLTPASRDSRWSLSPNHTHGHVKPGESQKFTFNV
RYRGKMNDESYQGIELILDQDFLAKTTRYAIPQVRTVVEFSKPE
>A0A485DGG0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia enterocolitica|TrEMBL
MESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFASGISRLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLVGE
NWQILLLDSQVFGVPYGELSEYQLEWMERCLMAHPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGRLETEVRRLASDEFCPDMDSDGY
>A0A741Z605|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar 4,[5],12:i:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLFHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A702FEH7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella bongori serovar 44:r:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLTDAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELHANGLLETEVHRLQDTRFRPDTASEGY
>A0A0A0CRR9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus luminescens|TrEMBL
MESQFELPVVEGTTAKILQITDTHLFASKEDTLLGINTYRSYQAVLDAVLKQNADIDLIV
ATGDLVQDQSLEAYRHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGK
HWQLLMLDSQVQGVPHGELSEYQLEWMKKCLDQYPERYTVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQGYSRVKAMLCGHIHQEMDMDWNGIRMMATPSTSVQFKPHCTNFTLDTVA
PGWRYLELSISDRGEFGLTTQVHRLESNEFCPDLDSDGY
>A0A7J0AZR3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alistipes sp|TrEMBL
MKKTATLLTAVCMVSCSAFEYHPYTTDVRGETGINTKNIKLIEDRFENSETVVFAFLSDT
QRRFDETVDAVESINSRGDIDFVIHGGDISDFGLRHEFEMQRDILDHLSVPYVVMIGNHD
YLGTGNRVFETVFGSYDFAFTAAHTRFVCLNTNAIEVDYTPGIPDFDFIDTELRSLSPDV
RATVFAMHIPPFAEEFNNTTAEEFEYYARRFPSLRFCIYGHNHRLAEDDLFGDGTIYYGV
PDIGKRIYYVFTIDSEGYDVETVGF
>A0A6N0LJF8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. 10FS3-1|TrEMBL
MKNLAQFESESVQDWTLIQITDTHLMDQPDLSFAQINPEYSFQQVMQHIQTHFPQMDALI
HTGDLAQVPVADTYARYLQSIQALNVPYYQIPGNHDDARYFPFYRNTDEAHAIRLGTWSL
ILLNSAVADQVDGWIEQAQLDQLDQLLTEHRRQHIVIACHHHPFAMQSRWIDQHRLKNAD
SLKQVIARHQNVKLVLFGHVHQDSCHAWQGVAFLSAPSTSVQFKPRSENFALDQAAPGYR
VVHLYQNGGFETHVQRIAFSEQNINTEISGY
>A0A7X4WC42|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium halotolerans|TrEMBL
MQTYSLPQDNSDSVLLLQLTDTHLFADATGSLLGVATKDSFHAVLDEVAAQLRPFDAIIA
TGDISQDHTPASYQRFADGIGRWVQPCFWLPGNHDYQPSMKSVLPSPQIKACDQVLAGEH
WQVILLDSQVVGVPHGELSQAQLQMLDQALAAYPDRHALVLLHHHPLAAGSRWLDQHQLK
NHQAFWQVVSAYPQVKAVLCGHIHQELDVLHQGVRVLATPSTCIQFKPDSNDFALDQSNP
GWRWLSLQANGEIDTKVERVRQRSFSPQFDAAGY
>A0A6A9R589|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas stutzeri|TrEMBL
MPGAPLTAVEDSVLLVQLTDSHLFAEADGKLLGMNTCDSLKRVVELAIEEQPRIDLILAT
GDLSQDGSVASYQRFRQLAGRIEAPARWCPGNHDELGAMREATRGSELMEPVLEIGGWRV
VMLDTLVAGSVYGMLRGDQLELLDRALDEAPERHHLVCLHHHPVSIGSRWMDSIGLRNPE
ALFGVLDRHDNVRALLWGHIHQAFDQSRNGVRLLATPSTGVQFTPQSEDFQVDSAAPGYR
WLRLYADGRLETAVSRVSGIAFEVDYSVKGY
>A0A250VC72|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces olivochromogenes|TrEMBL
MRIVHISDLHARTRWEADQEKLLRAFLRDVTEFHRQTPVDLVVFSGDLAFAAQPDEFGFA
RRALLDPLQDALGLDRERLILAPGNHDVDISKIEKYQEKGLLAGLTSRDAVNRLLDGDGP
SNYLERMEPWLAFHADYYDGTAVRRHSPLVTEHRITVDGVEVAVACLTSAWRATGEGDDA
DRAHLIVGDRQAAAAADGVGDAGFKIAVMHHPLDWLSDFDRRDVSRELGRFDVLCTGHVH
RADPLGVTGAAGSLLHSAAGSLYQSRDHPNAYSVIDTDPAHAPKSFTVHVRSYFDGRDAF
AEGVDVVSGGKQHITLGEPVRPGSVTAPGATTPGEPAATRTSADLAAEWLLDAVRERSLL
LGPDRWQQDMDELLVPPVLLPVPLDQYLALAEAEEGGKLKPDDLMTSLPEFRHFVIVGDE
YSGLTSALQWLSYAAYRREAQCAPVVIDFNAVEQGPNGVEREVRKQLAMAGVGVGKRDPL
PRMALAVDNVDPRADKRFRHLLKFMAQQPQNTYFFGSRTAASHRLCEEIGREGPAVRTRY
IGLFGRRELRALVRMVRPEEPEAEVTEMLDLLSRGGLPRTPAMLAALVSLAGQGDWTDGI
NNTAILESYLGMLLGRGDTSIDRRFELDFRDLQDILSCLTEHLMLSGKDALTRMEAERFL
LEYFQGLGWSEPSSVVLDALIAKRILGQRDGMIYFCQPMVRPLLAAYRLDSSAELRGLVL
AGPLDHGQVIRHAAALRRNDMALLRTVNEMFRSLRSRVGDGSSDLFAARAAKDGWRGSED
AEAVLEEFWPADMPYEAPEPSAQVREDFTVMLDELKDHVDTIRAMAEVERHGDAFSRSDF
EAFSEGLDLLADVLRSSELVRDLDLKRQTLQLTLNGYGVRAALMATEWKVRGIRKVFEEA
LAGSVDRLELTADDFDELLSRIELFSPVISSYTALSQALASGKLSKLTDEALSERDFVEQ
PGQALMAVLLVRRMGDRDWIRHASRVVKLHGERKVVSEVLRFFAMSSYLQSDLGREDVTA
LESLLADIATQRKELPSGPARGQHRTHMLQGLRNRRMRALQQQGRRWIEPV
>A0A2R8AC02|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pontivivens insulae|TrEMBL
MSKLIVMTDLHVTTGAPIIGIDPLARVEEALRHAGSHHPDAAGLVVTGDLVHSADQTEYD
RLAPVLATAPWPVWVIPGNHDRRAPLRRSFPNAPRDAAGFMQAVVDLPDARLILLDTLDE
TDGAGHSGFICSARMEWLSDQLAQADTRPTLVFLHHPPFRTGFDGMDAIGLRNAKELRAV
LHAGGVAHVFSGHIHRTITASVDGLSLSVFKSPCHQMPMLLGEPGHGHSIAEPGAYGIVC
VNSDGIVVFTEDFSLPPSTNGQH
>A0A7D6HPX5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arsenophonus endosymbiont of Aphis craccivora|TrEMBL
MDSLFKLTTKQKRLVRILQITDTHLFANVDDTLLGVNTFGSFHAVIDAILACHENVDLVV
ATGDLVQDQSASAYQHFAEGIKRLSAPCVWLPGNHDYQPAMVATLAQAGILPSKQVLIND
NWQILMLDSQIQGVVHGKLSKQQLLWMKRCFDAYRERSHLLMLHHHSLPSGCTWLDQHSL
RNSHILADYLNQYQQVKAILCGHIHQEIDEYWQGVRMMATPSTCIQFKPHCTNFTLDTMA
PGWRYLDLSINDNGENVLDTQVFRLDSDKFRPDFDSGGY
>U3A6L5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio proteolyticus NBRC 13287|TrEMBL
MNVSSSSTDQRIKLLQITDTHLFAPEDGSLLSVNTAESFHAVVAAILERQVGFDAILATG
DISQDHSRESYEKFERGIQPLSQPCFWLPGNHDYKPSMGAILPSQQIQTAEHVLLGEHWQ
MILLDSQVVGVPHGRLSDAQLTLLDNQLSAHPDRYTLVLLHHHPLLVGSAWLDQHTLKDS
EAFWEIVDKHSNVRAVLCGHIHQEMDLQRGDVRVMATPSTCVQFKPRSNDFALDRQSPGW
RELELCQDGTLHTQVQRLPEGHFLPDFSASGY
>A0A4U1KQP1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Azotobacter chroococcum|TrEMBL
MPSPAPSVADSSLLLVQLTDSHLFADMEARLLGMQTEDSLQRVIELVRREQPRIDLLVAS
GDISQDGSDESYARFRQLCAPIAAPLRWTPGNHDTREALSRASAGSECRQPIVDLGNWRI
VLLDSALPHAVPGFLEPSELALLERALAEAPERHHLICLHHHPVSIGCHWMESIGLRNAE
ALFAVLDRFPQVRALLWGHVHQEFDRMRRGVRLLASPSTCVQFTPGSEDFSVSDQAPGYR
WLRLQADGRLETGVSRLTDYRFQIDYGKGGY
>A0A3P9P5W3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poecilia reticulata|TrEMBL
MRREAACFSAAFRSNAQKSLGVKQANGRSRTCASSFDVENGLSVGRSPLDSQTSPGSGLV
LQGNFPHSQRRESFLYRSDSDFDLSPKTMSRNSSTASDLHGEDMIVTPFAQVLASLRTVR
SNVAALTHLQDRVVNKPNMNKVCIMKRFTRVLSHPSSKRVN
>A0A7R6V5G1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nitratiruptor sp. YY08-10|TrEMBL
MKRRDFLKATCTLPFAIPLLAQENRTFRFLHITDSHMDLSMPHTVKAMEHLVDVVNSRFS
HIDCVLFGGDNFNNTASGDKDAKVFKSILDGLKVPYYCVRGNKESTPKGDNQIDAKEFAR
LFFDQKGMKVSGRDWMVQHNGYVILGLDSTIEHSGAGIYTKETIAFAKKALDLGKPTIIL
NHHPYLNYWGGTDPKDIHKYVLQNTKEVQEKLFRYPNLILTLSGHKHIDNVSHIGHVQVI
ATRAFKAAQTLYRNPMRYIEIDGSTVTQKLITT
>A0A385B3R5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. phDV1|TrEMBL
MPSLPTQSTDSSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIERVLQEQPQIDLILAT
GDLSQDGSEASYQRFRQLTSAIDAPTRWLAGNHDEIPPMQAACQGSELLEPVIDLGAWRI
VMLDSSIPGAVPGFLADGQLELLERALSEAPQRHHLICLHHHPVSIGCKWMEPIGLRNPD
ALFAVLDRYPQARTVLWGHIHQEFDQQRGNLRLLASPSTCVQFAPGSEEFQVSSEAPGYR
WLRLYADGTLDTGVSRVTGITFEIDYSVKGY
>A0A0U3JQ87|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea vagans|TrEMBL
MDSLLTLPAANGADIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAITAQQHDYDLII
ATGDLAQDHTVEAYQHFVAGITRLPKPCVWLPGNHDFQPAMVDTLAEAGIASDKHVLLGE
HWQLVLLDSQVFGVPHGMLSEYQLEWLDIALRKHPERHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLQHFPRARNLVCGHIHQELDLDWHGRRVLASPSTCVQFKPHCTSFTIDNVA
PGWRWLTLKADGLLETEVNRLQSDMFRPDLDSEGY
>A0A522WZ18|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacter sp|TrEMBL
MTNNLACLSILQLSDLHILPTAEDKMLGINTEHYFHACIEQAVRLRAQKVGKPFDLILLT
GDLAQDPCSESYRRILTALDAYETPCICLPGNHDDYELMQQVLNTDRINCRKQVLLDSWQ
LISLNSQIPGQAGGRLADEELVFLESCLVDNPDRHALVAVHHHCLETKSPWMDTMIIANS
REFLALVDRYPQVKVIINGHIHQVMDIKTATLRVLGVPSTCFQFVPESTEFSVNDMAPGY
RLIDLHADGRVESEVVRLPESLADLQTNTDGY
>A0A8C9UPF9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Spermophilus dauricus|TrEMBL
MGHQQAVQPLGGVAAPSLPPRWAPPPRLSRKGPERRLLALQPPRCPGHAGSPCASPGPWA
RLPSGLPARRPXXXXXXXXAPAPPPSLPISVSLLHPPPRHPPRGPADCPFPAVWPRAGRA
EAHVSPDPRWPGTGGLRRRPPPPGTQLPGSCALTITSSAFSFDLENGLSRGRTVLDPPSG
PGLGRGAQAPAPHSQRRESFLYRSDSDYELSPKALSRNSSVASDLHGEDMIVTPFAQVGS
SPTPTTFRLQLPATSDHLSPDRSSPKLALETLEELDWCLDQLETLQTRHSVGEMASNKVG
PTWIESSRSGNQVSEYISRTFLDQQTEVELPRAAPEESQRPMSEISGLRGLPHSASLSAA
TVPRFGVQTDEEGQLAKELEDTNRWGLDVFRVAELSGNRPLTAIIFSIFQVLSCLCLPRP
SDQHSARHSARDKTPPALQGQRSPGLGGFGEAGTGGRLRVSGSRLCADSELALMYNDVSV
LENHHLAVGFKLLQAPNCDIFQNLGAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVE
TKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRER
ESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQS
KIPRSPVDTAVSSERGLPDRFQFQLALEEAEEEEEEEEEALERQPSGNSLSYRGWPRTYD
PPASASCLAGLPAPAAMPGCYLKYKVSAGASAHSPADGYFWEPPCRQRAAASVREVWELN
SVAVLTSSLGPPRRVPTQRADLTEGLRVGREPRSRAGFIVLYFCCCFSVFSQFSAVGL
>A0A3Q2UBS7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gallus gallus|TrEMBL
MVTTPIYSGPQPPLPPPRCLTPRSMESISEFSTRAAAPAVPPPSHTAPIPVCATAVVGGM
CVSAPHLGDAAPGSGPSPGWQRGQRWLSCTGGGTNPQLSHRARRSHNAALCPRTIGDAGQ
RLTAGPGDAARRPLPVPEALLHRVGPALWGDGDGRPRSFPGVAHPGPHGGTGRGRMLATL
AVSPRAAVPMTRGQRGGSCRGGSAGPPSPSPCLSTPVRCAAPDGTAPPRPQGPALGFPRG
FCPSMSPGSVPRTDPLRDAALWATADGDFRGLAAVGDGGVGDVGTRDDGDTGRPTSSSGT
GPSLAVAVNGDSGGVSASPVPYPCSFDLENGPPGRGPLEPQCSPGAGLVLQGAFSHSQRR
ESFLYRSDSDYDLSPKAMSRNSSIASDLHGEDMIVTPFAQVLASLRTVRTNVTVLLHLQE
RVGTKRASSSSLPSASRAGLSGECPNGDKRGLGGGAGRCPAVGVRRSLSRGVQ
>A0A3N0G361|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dickeya undicola|TrEMBL
MESLLTLPVARGARIRILQITDTHLFAGERGTLLGVDTYRSYQAVLDAIVAQQWQFDLIT
ATGDLAQDHTQEAYTRFADGIRRLNAPCVWLPGNHDFQPAMVDVLARSGIAPSKHVLLGE
HWQVILLDSQVFGVPHGELSEYQLEWLERSLQSQPERHTLLMLHHHPLPSGCTWLDQHSL
RNAHSLDALLARFPRVRTVLCGHIHQEMDLDWNGRRLLATPSTCVQFKPHCTSFTIDNVA
PGWRYLELLPEGEVETQVCRLEGNEFLPDMDSDGY
>A0A7X0SZE7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea stewartii|TrEMBL
MDSLLTLPATTESEVRILQVTDTHLFAGKHESLLGVNTWASYDAVLDAIIAQQRDYDLIV
ATGDLSQDHSVEAYQHFVEGISRLPKPCVWLPGNHDFQPAMVDTLAEAGINAHKHVLLGD
HWQVVLLDSQVFGVPHGMLSDYQLEWLNTTLARYPQRHTLVLLHHHPLASGCTWLDQHSL
RNPHQLDAVLQHYPLAKTLVCGHIHQEMDVPWQGRRVLATPSTCVQFKPHCTSFTIDTVA
PGWRWFTLHNDGQLETEVNRLTTQAFRPDLDAEGY
>A0A6C2E2U7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudanabaena sp. UWO310|TrEMBL
MKGKISYGSFVSIAQLTDIHLFGDIESSLLGIQTEASFQEVLTAIKRNLPQIDLLLLTGD
LTQDGSTASYDRLRRSLDRFGIHAYCLPGNHDDGILMKRHLPSDYVHLSRSLDVGKWRIL
LLSSVVVGAVHGYLADSELEWLEDNLKAYPERPTLIAFHHPAITLGSRWIDGICLENQDQ
FWEICDRYPQIEVVINGHAHQEFDEIYETPHNSVRCLVTPSTCIQFEPKNHKFQIDSQPP
GFRHLRLYPNGAMETEVYRLKVGSFHPDLAAIGY
>H9G6Z0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anolis carolinensis|TrEMBL
QESLRPARTQIFLPPAEDAVQKLAMETLEELDWCLDQLETLQTRHSVSEMASNKVRNPTF
PPSEVILNLILNLNPPHPEPVSQNPHQSHSEAESQQLLYKQHEVDIPTSVPKEKAKERKR
RPMSQISGVKKLLHSSSLSCTAVPRFGVRTEQEGLLAKVGQPGPWGAPPKRYW
>A0A8C5VGK4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcebus murinus|TrEMBL
MRFHQDQLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTREAQAVLACFLDKHHDIIIIDH
RYPRQLDAEALCRSIRSSELSENTVIVGVVRRVAREELSVMPFLAAGFTRRYIENPNIMA
CYNELLQLEFGEVRSQLKLRACNSIFTALEKSQEAVEITNEDHIIQYANPAFETTMGYQA
GELIGKELGEVPINEKKADLLDAINSCIKIGKEWQGVYCAKKKNGDNVQQNVKIIPVLGQ
GGKIRHYVSIIRVCTSNNKAEKISECVQSDTNTDSQTGKHKDRRKGSLDVRAVASRSSEV
SSQRRHSSMARIHSMTIEAPITKVISIINAAQESSPMPVTEALERVLEILRTTELYSPQF
GAKDDDPHANDLVGALVSDGLRRLSGNEYVLSTKSIQQVSSSIITPISLRDVPPRIARAM
ENEESWDFDIFELEAATHNRPLIYLGLKIFARFGICEFLNCSESALRSWLQIIEANYHSS
NPYHNSTHSADVLHATAYFLSKERIKETLDPMDEAAALIAATIHDVDHPGRTSSFLCNAG
SELAILYNDIAVLESHHAALAFQLTMGDDKCNIFKNMERNDYRTLRQGIIDMVLATEMTK
HFEHVNKFVNSINKPLAALEESEETKKNQEAINSMLRTPENRTLIKRMLIKCADVSNPCR
PLESCIEWAARISEEYFSQTDEEKQQDLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDA
WDAFIELPDLMQHLDNNFKYWQGLDEMKLRGLRPPPE
>A0A8B7G8N3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcebus murinus|TrEMBL
MGCAPSIRISEARAVYRGKEAEVALGPAGPPPSGGPCLTQGHRTAALPPARGASLADSEP
RDGSGKKVAVAEVQFGPMRFHQDQLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTREAQA
VLACFLDKHHDIIIIDHRYPRQLDAEALCRSIRSSELSENTVIVGVVRRVAREELSVMPF
LAAGFTRRYIENPNIMACYNELLQLEFGEVRSQLKLRACNSIFTALEKSQEAVEITNEDH
IIQYANPAFETTMGYQAGELIGKELGEVPINEKKADLLDAINSCIKIGKEWQGVYCAKKK
NGDNVQQNVKIIPVLGQGGKIRHYVSIIRVCTSNNKAEKISECVQSDTNTDSQTGKHKDR
RKGSLDVRAVASRSSEVSSQRRHSSMARIHSMTIEAPITKVISIINAAQESSPMPVTEAL
ERVLEILRTTELYSPQFGAKDDDPHANDLVGALVSDGLRRLSGNEYVLSTKSIQQVSSSI
ITPISLRDVPPRIARAMENEESWDFDIFELEAATHNRPLIYLGLKIFARFGICEFLNCSE
SALRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPMDEAAALIAATI
HDVDHPGRTSSFLCNAGSELAILYNDIAVLESHHAALAFQLTMGDDKCNIFKNMERNDYR
TLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLAALEESEETKKNQEAINSMLRTPENRT
LIKRMLIKCADVSNPCRPLESCIEWAARISEEYFSQIRKNY
>A0A7U9R159|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lachnospiraceae bacterium|TrEMBL
MNQIKFATFNVGGGVPYRKMPEFQEAWFNAADYMGKLIADQGLDIVCFQEVLTGDETYSS
MCSEIGRKSGLKYYMEWMLSDSHIVTGRKMGVAIASKFPITESRRFRLENPNIVHRLDSG
EIYRSHEKGFLIVEIRTDAGRICCVSGQCIPFHTFCRDAAEFRYIYSELERMLLKLAEDN
RHVIIGADLNVSREELRLFMPELMQRYSCLPGRNMATRPNGRGDDYILYKADKGQVEFRL
VKTCFDHYGCVGTFRKEYFTKNEELEKMGWEETGEKMAVEQRKGSHVYVLHLSDLHFSGE
SSNDMDKKIPAKLDSNLGKEEWLENYIQDLPTKPDYVVVSGDITVRGSAAGFEKFHQVMI
RLIGKGKLPSANKFIIVPGNHDVTAASSVKDKNRWVNFKSIIGNTYMTPWIVNGDYDYGA
MKRWVDAAMEAAGPLQGGNMINPETRAHISVPFLVDKENKILFYAFNSAFPSQIEIDNKE
VKGIIDHYKKYGEDDKEFSFLVQAMEKRMKIDPARIIDEEIWLFIYCMKKLKHKLMLEQE
AGGEYTDYIKIAVLHHHITSIACSEEIKEFELLTNAGKFKKILADYGFHMVLHGHKHWNE
VYKDTAVSGGSSLAETNDGRALLGISGGTICGTPCNGKSAGFYWLDFSMDRKTVKPYYHE
VLSYDRDNVKEGREYYLAGTGEKCASNDAGRGRAAGGAGSAAASASGCRAITGDNAIIHG
EKKYKTKQTPFYKGNNEKQDTEDYVGGAERGYSYDWAGRNSAGEETQKTYKPKELYSRME
KALMDNIHYNKEGDKKSFGWGRLLIMKKPNRISMMATAYGLIIADMLNIHTISYMAKKKD
IINTLWNFRLEEGGFKASSQAGEASIEATVCALRAFYRVRDMEKFEITLEDLNSLIEKEK
LNEESSITTLTLALDVLCECCPNHEKVGGLKDVIIQKAYVGRDGRPLYWAESVAEEEEGA
SICTALAVIALLNYAKSSNGWKQMVAYLHNCGEWLLRAKWKNWEETISHKSGGPLTYYHY
TAFWGIIALLRLGYGSDEKRIKDEMQGILEKETDGVWAWDKGLDYPIWTIYNAILMMNEY
VLNEIRI
>A0A4Q7DFP2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cryobacterium sp. SO1|TrEMBL
MRERSKFTILHLSDVHATTGELLYGQVDGLARLRQVGEYVVAAGVTPEAVVVTGDLVQRG
HSAAYENVDRALRDLGERVGAPVFTVLGNHDSPRHAAGLTGHMQGHYRATTVGDLRLVLL
DSSSGSLDPDQLVWLRGVLAVPFGMGTVVALHHAPIPSPLPTLSKIGLRDPRLLAHALRD
SDTRLILAGHYHHPMNGLFHGLPVAVGPSLAYHQVMNAGPATVSGHDFAMFSLVQVTADQ
ISTAPVSLQAGHPLFSTTVPPLTSTSHR
>A0A4P6M0R5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Blautia producta|TrEMBL
MKKFVTTTYRITTDKIKRHPLKFVMISDLHNVVFGEKNEPVFDRIKALGPDAVLIAGDLV
LGKTDASLKPAAAFLGEAAKLAPVLYAPGNHEQRMKLFTEEYGGRFSAFEKKIKQMGVSY
LENQRTVLQIKGETVAVTGLDLPYKYYSRGLQRGPGRAELEHLIGRPDKEVYEILLAHTP
RYGDEYFAWGADLILSGHYHGGVMRLPFLGSVISPDFRLFPRYGYGEYRKGPKTSAKKAR
PGQKITGSEQIMITGAGLGEHTMPLRINDPRELVVLECLPKEV
>A0A731NAL1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae serovar 42:r:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGD
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A7U9DDR6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. KTE159|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILMLDSQVFGVPHGELSEFQLDWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A5R8Z7K3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas mosselii|TrEMBL
MPQPLASPSPIHVVQLTDAHLFADPAGTLLGLNTRDSLTHVIGQVRREQSRIDLLLCTGD
LSQDASSASYEAFRDLTAVLGAPSRWLPGNHDEALAMNQVAPELVQAVTDIGAWRVVMLD
SAVVGATFGWLADEQLAALDQALATADGRHCLLCCHHQPVDIGCAWMAPIGLRNADALLA
RVGTYPQVKAVLWGHVHQPWDQLRQGVRYLATPSTCIQFTPGSEDFKVSEEQPGYRWLRL
HEDGQIETGVERARDFVVTLDFDSPGY
>A0A679J0M0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium bullatum|TrEMBL
MFHLIFGLPCLYVITRVLWPLPWPFAVKAGVALLLLIASQYHLWSRLSSGSVFAPEFPRS
LIVLFNWAFGAIALLAAMQLALDVVALASRLLPGGGWAIPAGWRYVEAALAMLLSAVAVQ
QAVRVPPLKDVTVEIENLPAGFDGFTLLQLTDLHLSRLFPAAWAQEVVTRSNALGVDLVV
VTGDLIDGALASRRADVEPLRGLRAPDGVWVIPGNHEYFFDYAGWMRRYAELGMGVLENR
HTVLRRGADALVLAGVTDLSASHSGRPVHDLDAALAGAPPDAPIVLLDHQPKDAARAAAK
GVALQLSGHTHGGMIRGLDRLVARANAGFVSGAYAVGGMTLYVNNGTGLWPGFALRLGPP
SELTRITLRGKPRS
>A0A554TLG4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. KBS0710|TrEMBL
MPSVSTVNPDAPALLVQLSDSHLFAEADGTLLGMNTRDSLQRVIGLVREQQPQIDLMLAT
GDLSQDGTLESYQQFRDLTRQIDAPARWIPGNHDEPQVMAHAAVHSDLLEPVVDIGQWRV
TLLDSAVPGSVPGYLQDSQLQLLAQALSEAPNRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVKAVLWGHVHQEVDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERVKGFEFTVDYGSNGY
>A0A8C6YS09|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothoprocta perdicaria|TrEMBL
MCGFAHKSEPLSRGGSGSAGVWHRVRWNRGEPAALGRPRGPASLRPRGRMSARLLAEEPY
QKLAMETLEELDWCLDQLETIQTYRSVSEMASNKVSAAAAGPLPPGTTGAPGTALSSRRL
>A0A287D411|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ictidomys tridecemlineatus|TrEMBL
MSLPTSCEHLTLGKVARFRSAYIHGSPYAINKPIDIKPQRRRFDVDNGTSAGRSPLDPMT
SPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVL
ASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLKELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFR
IAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADV
VQSTHVLLSTPALEAVFTDLEILAAIFASAIQDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKXXKKNVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRER
ERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQS
TIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEESQPEAPVIDDCSPDT
>A0A6I1U8Y2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. SZ57|TrEMBL
MPSAALSSSVLLVQISDSHLFAEADEALLGMSTRDSLEKVVDQVLAEQPHVDLVVASGDI
SQDGSVESYQAFRRISGRIDAPARWFAGNHDELPQMEQVAQPNGLLDPVVDIGQWRVTLL
DSAVPGSVPGFLAAAQLQLLEQSLSEAPDRHHLVCLHHHPVAIGCEWMAPIGLRNADALF
AVLDRFPQVRAILWGHVHQEFDQMRNGVRLLASPSTCIQFAPGSVDFKVDTTAPGYRWLR
LHDDGRLETAVSRVVGLEFEVDYGGTGY
>A0A3N0XSG9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anabarilius grahami|TrEMBL
DSKDLLGCTSSGATLGVDLWRGPRRHSGTLVLPPLSWRQTERARSPQDHVSRPTSLGFIT
PPRIDITPVPPDSQRIEMSLDTGCQSDVKEHTAGARNSPQNSPGMFRKLVVNKTVRQRRR
FTVAVSHTCLEVENGPSIGCSPLDLQASPGSGLVLHPNMASHGQRRESFLYRSDSDYDLS
PKSTSRNSSLVGEQLHGEDLIVTPFAQVLASLRTVRNNVSFLTNVPCPSSKRSPVSSQPP
MTKGNLSATTTHLFADLRLKPEEARRLGRSSRRRLKRLLQRTQLNSPVGASAGALADCRP
ERRPRVAASRFPLPSQRVSCRHPAHPQRAFPAV
>A0A3B7LS95|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter chinensis|TrEMBL
MTSSALTPRQQSWTIIQITDTHLMDQEDLDFVSINPEQTFKAVIQDIMEKYPEADAIIHT
GDLAQVPVVSTYERYINFMETLNVPFYQIPGNHDNSECFPFYDHKDEIHTIQLGQWSICL
MNSAVKGKVDGWVEQAQLEQLNQILQDNQDQSIVLACHHHPFEMKSRWIDNHKLKNTEQL
TDILGQHNNIKAVLFGHVHQDSLHEWNGIPFLSTPSTCVQFKPLSEKFALDEQAPGYRVM
HLHENGRFETQVHRISGLIQKINGEISGY
>A0A7R8YM28|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hermetia illucens|TrEMBL
MEDDRDESASIGCMGKFAMFFRHTSKVSINNTSTVDASSPSTKKRGYKRNRGTNNIITDR
KNSISKNNSKSESSLIDLKKQLEARMIEGSATEATGPHTKADILDNIVFSQSTNRRNDSA
DSDDTKLLSGVTATGDTGDKASRSDKAINNATRGTTIIPPTPYGNIPIIYNVCNTKTVGG
EKEKNIEIRDDDYDSSEEVLLRKRVSISRSDKDFADEMNDSVPPLRRPRQMRTYGSASGT
PIPIRPDIAELIRTLDPDALRINQLISDDKANTGGGVEGWDTQTVGISVQGLDIHCNNKS
SDGVNPITKSRPAGTSLFERRVPTGERLSLYIGGKTDLGNGHRKKKEKPLMDLKHPTVLP
PNPQLKALLIFHKADSVCETFNNACHRHQLEVTLVKTKETALEAFQNNTAGSHHLIIIDA
RYPKYLDAEYIARSVRHTPGCHFTTIIGIVKKSFFEKDEASLNALLDAGVNRCIVETQNI
SVCSTELKQVLHSIVRPQHVMSTQQALYTALHRLKEVLIITDDLLRIQYANKSAERLLNM
RLDEVISRPLSDIFLSDLSSLKNRRDFDGILTVKRKGHDGIAMHVRGVPVACIGRAPTHY
VLNFDVPGGQADFIASLPQPKEAPRGSLHSIRRGSFDVRSVASDGLRRTSLAKLTSLPLE
APITKVVNLLSQVQENCSQEEARLIDKVLEFLKREGLYSPQMKEIKTEDPIATDLIGALL
TGPTNLYSSRRSSNDSIMRVSTSRASGILPAKMKANSQIMAMLEESLDWDFDILKLEEIT
EKRPLLYLGMEMFRRFDVFATFNTDENTFKTWLAVMEAHYFAQNSYHNSTHAADVMQATG
VFLHQLAEKNLAMDRMDEATALIAAATHDIDHPGRSSAFLCNSDSPLAILYNDLCVLESH
HAATTFKLTLGDDKINIFKNLDRETYKVARSVIIDMILATEMTRHFEHLAKFVSVFGTDE
PRDQLAQSEDDNQILIRRMLIKCADVSNPARPLPYCVEWARRIAEEYFTQTDEEKARSLP
IVMPMFDRATCSISKSQIGFIEYIIQDMMHAWDSFIDMPQLIHHMQYNYSQWKKYEEQGI
HTLADIKNKQTTLNAKKSIAK
>A0A0K8U7D3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bactrocera latifrons|TrEMBL
MGCSPSTLLSHNNPDGDEAHHATDTQLSGAGTASGGGGGEKESSLFFCIKLRRSRPLRRC
SQHNGGGDGSAGSGGTGSAINGDDLLGHGNMCNQALLNPAQTKNEADYDKMCSGKKDSIV
TVAALGNFTHTVVRRATGSTGTSGTTSSGGASKPEKRKSSIALTPEDESIERSLMDVKFP
TVLPPNPQLKALLVFHKSDNICEVVTEACHRQQLDVTVARTKEGALDTLTNTNEEFYHLI
IIDARSTKHLDAEYIARSIRHTNGHHFTTIIAVVKKSFFEKDDVLIALLDAGVNRCVPET
TNLSMCNIELKQILHSIVRPHNVMSTQQALYTALHRLKEVILITDNHLRIQYANRAAERL
LNMRLDEIISKPLADIFISDVSTIMIHGRKNKEFDEILTVRRKGQEDVAMHVRVIPVACI
GRTPTHYVFNLDVPGSHGDFVATLPQAREAPRGSQHSIRRGSVDVRSVASDGLRRTSLAK
LTSLPLEAPITKIINLLSQVQENCSPDEARLIDKVMEFLKREGLYSPQMKEIRTDDPIAT
DLIGALLTGPSLYSSRRSSNDSIIRVGGRQSTCMPAKMKATPHIMELLEESLSWEFDIFK
LEEITEKRPLLYLGMEMFRRFNVFATLNIDENVCKSWLAVIEANYHANNSYHNSTHAADV
MQATGCFLTQLAAKDMGMDRTDEAIALIAAAAHDVDHPGRSSAFLCNSRNTLALLYNDLC
VLESHHASITFRLTLSDDKVNIFKNLDTESYKSVRSVVIDMILATEMTRHFEHLAKFVSI
FGSDEEPKDIVQSEEESSILIRRMMIKVADVSNPSRQPSYCIEWARRIAEEYFTQTDEEK
AKTLPIVMPMFDRNTCSIPKSQIGFIEYIIQDMMHAWDSFIDMPQLVTYMQINYSQWKKF
EEQGVHTLADVKSKQHSLSVKKSAK
>A0A090IQ82|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aliivibrio wodanis|TrEMBL
MLSETLLNNEDSPIRLLQITDTHLFAPEDGALLGVPTLKSFRAVVDQVQQRTPDFDAILA
TGDISQDHTVQSYQHFVDGIEPLEKPCYWLPGNHDYKPSMSNVLPSSQIQACEHVLIGLH
WQIIILDSQVVGVPHGLLSSKQLILLDNALTQHPDRHSLVLLHHHPLPAGSAWLDQHQLK
DNQDFWDVLNQHSNVNGIVCGHIHQELDRKVNGVRLLATPSTCVQFLPDSDDFALDSQAP
GWRTFELFPNGVIETQVHRLNNSDFSADSDAGGY
>A3N3N4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinobacillus pleuropneumoniae serotype 5b (strain L20)|TrEMBL
MSSFYSLGKKEPVVRLLQITDPHLFTSESETLLGVNTTDSFQAILDQIRQSEFEYDLVLA
TGDLIQDHNPEAYHRFAQMVKPLAKPIFWLEGNHDLQPHMGLYLAKYPHISPAKHILAGE
KWQIILLNSQIAGAASGHLSFGQLSWLDKKLAEYPDRYSLVVLHHNILSTRSAWLDQHCL
NNSEQLAEVLRHYPNVRAILHGHIHQEVDDIWQNYRIFATPSTCIQFKPNCDDFTLDLLP
QGWRELNLFDDGHIETQVKRLNSNEFLPDFKSKGY
>A4Y3G8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)|TrEMBL
MLKEAVSYSIAEGESVRIVQVTDPHLFADPEAQLLGVNTSKSFAAVLNTIRAVDYPAHIM
LATGDLSQDYSAESYQQFVRAVTPVGLPCHYLPGNHDDPRIMYLHMQGEQIFGQQRILAG
KWQILMLDSTVRGKPGGHMAQSQFELIEQAIAAHPECYTLLVMHHNPILVNCTWLDQHCM
DNGAEFLERVAMYPQVKGLLWGHVHQRIDTHYEGPHGALQLMATPSTCIQFKPLSPYFAL
DGLQPGYRLLELKADGSIGTNVYRVPGNHFFPDNDSSGY
>A0A6G6TER0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteus sp. ZN5|TrEMBL
MESQLELSVKHKNTVRILQITDTHLFANVEDTLLGINTYRSYHAVLNAIREQSLDVDLIV
ATGDLVQDQTFEAYQHFADGIATLTPPCVWLPGNHDYQPAMIDALNQAGILSAKQVLIGD
NWQMLLLDSQIQGVPHGELSDCQLDWLTRCLESQKHRETIILLHHHPMPSGCTWLDQHSL
RNSQELAERLKDHSQVKMMLCGHIHQEMDEMWNGIRLLATPSTCIQFRPHCTNFTLDTVS
PGWRYLEMSLSSDEKGKIDTQVYRLAGTEFCPDLDADGY
>A0A6J8DHV6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mytilus coruscus|TrEMBL
MSHNNKLHRVLSTSVLRIPRSRYSFWQRHADDLIVTPFAQILASLRSVRNNYISLTNVQA
PRESSVLCILFVIYGPADFQFSDSSVLCILFVIYGHAGLQFSDSSVLGILFVIYGTAGLQ
FSDSSVLCILFVIYGPADFQFSDSSVLGVLFVIYGHAGLQFSDSSVLGVLFVIYGHAGFQ
FSDSSVLCILFVIYGHADFQFSDSSVLCILFVIYGPAGLQFSDSSVLCILFVIYGPAGLQ
FSDSSVLCILFVIYGPAGLQFSDSSVLYILFVIYGHAGLQFSDSSVLCILFVMFGPAGLQ
FSDSSVLCILFVIYGPAGLQFSDSSVLGVLFVIYGPADFQFSDSSVLCVLFVIYGSAGLQ
FSDSSVLCILFVIYGPAGLQFSDSSVLCILFVIYGPAGLQFSDSSVLYILFVIYGHAGLQ
FSDSSVLCILFVMFGPAGLQFSDSSVLCILFVIYGPAGLQFSDSSVLGVLFVIYGPADFQ
FSDSSFIYGSAGLQFSDSSVLCILFVIYGHAGLQFSDSSVLGVLFVIYGSAGLQFSDSSV
LGVLFVIYGPAGLQFSDSSVLCILFVIYGHAGLQFSDSSVLCILFVIYGPAGMQFSDSSV
LCVLFVIYGPADFQFSDSSVLGILFVIYGHAGLQFSDSSVLCILFVIYGPADLQFSDSSF
SDSSDSSVLCILFVIYGHAGLQFSDSSVLCILFVIYGSADLQFSDSSVLCILFVIYGHAG
LQFSDSSVLGVLFVIYGHAGLQFSDSSVLGVLFVIYGHAGLQFSDSSVLCILFVIYGPAD
LQFSDSSVLCILFVIYGPAGLQFLDSSVLCILFVIYGPAGLQFSDSSVLGVLFVIYGHAG
LQFSDSSVLGVLFVIYGHAGLLFFSDSSVLGVLFVIYGPAGLQFSDSSVLCVLFVIYGPA
GLQFSDSSVLCILFVIYGHAGLQFSDSSVLCILFVIYGHAGLQFSDSSVLCILFVMFGPA
GLQFSDSSVLCILFVIYGPAGLQFSDSSVLGVLFVIYGPADFQFSDSSVLCILFVIYGHA
GLQFSDSSVLCILFVIYGHAGLQFSDS
>A0A3B0JHX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila guanche|TrEMBL
MGCSPSTLPPNASSSANANAGPTAANSVPLSLDATEKDGSRLFCIKLRRSRLRRCSCGGV
TLQQGGGDGNGSTAGSATCGSGAGDNLCHQVLLNPLQAKNEADYEKLSTGKKDSIVTVAA
LGNFTHSVVRRATGSTGTGTSGTSSSGGGGGNNRPGHRKSSLALALTPEDEPMDVYQRNL
MDLKYPTVLPPNPQLKALLVFHKSDSICEAVASACQRHQLDVTLVKSKEEALDTLHKSYA
TAQCYHLIIIDARSSKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAG
VNRCIAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQY
ANRATERLLNMRLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMHV
RVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDG
LRRTSLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEI
RTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKANPIIMELLEE
SLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNT
YHNSTHAADVMQATGAFITQLTNKDMMVMDRMEEAMALIAAAAHDIDHPGRSSAFLCNSN
SSLAILYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTR
HFEHLAKFVSVFGGEEPREHNPQSDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIA
EEYFMQTDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITY
MQINYSQWKKYDEQGVNTLADIMAKQPPMGKLGNSK
>A0A2X4XDT4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNEFDVILA
TGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNVAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAEFLPNMQEDGY
>A0A7H1NPA1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Entomobacter blattae|TrEMBL
MNNFTLAHLSDIHLPLPTEGLLFKQFLNKRALSYLSWQLRRRHHYLKTITDTIRKDILQC
APNLVAISGDLTNMALPQEFSSAAEWLEHSGFPQTRLVCGNHDAMVAVPPQEGILKWQRW
MMCEQNSLPFVTRLGPIALIEVNTALPTLPFMATGEIGENQIQQLEFKLSLTKQEGLCRI
VMLHHPPLKGQVARRKSLIDQKKFCSILAQYGAELVLHGHSHKITQVMLDAPNPIPVIGI
SSASHLTTNPNKRAAWNHITISRESSSWKIDVMTRQLSPEHTMHVFKHSTFIMPVAR
>A0A727YJT6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAVYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A6L5BZC6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas frederiksbergensis|TrEMBL
MDIQSKHQRRTDGPLNPDRRTLLKCSAWAGAGVIWALSGGVPRAFALDSSGNVTDPKALA
STFHFVQISDSHIGFNKEANPEPVKTLQVAIDKVIALPKRPALILHTGDITHLSKAEEFD
TAAQLLKGLPSTVHYVPGEHDTLDEGGGKLYLERYGKGTKGNGWYSFDDHGVHFIALVNV
FNFQAGREANLGADQLAWLADDLRAVSTSTPIVVFTHIPLWTIYQPWGWGTEDGDQAIAM
LRKYGSVTVLNGHIHQVIQKVEGNITFHTARGTAYPQPAPGTAPSPGPMTVAADQLRNYL
GVTDVRATQGEHPLALIDSTLV
>A0A7K4KRJ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Crypturellus soui|TrEMBL
SFQFKRMMNRELTHLSEMSRSDNQVSEYISNTFLDKQHEIEIPSPTQKEKEKKKRPMSQI
SGVKKLMHSSSLTNSSIPRFGVKRDQEDVLAKELEDVNKWGLQVFRVAELSGNRPLTVIM
HTIFQANHAVLYNLTCFSFFFQEWDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA
ADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYND
SSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKT
MVETKKVTSSGVLLLDNYSDRIQV
>A0A8F8FSW4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. MTM4|TrEMBL
MPASRGLPPQPPATIILLRFRQRRRVLAAPLIEKDSVLLVQLTDSHLFAEAGGKLLGMDT
GESLQRVVDLVLAEQPCVDLILATGDLSQDGSLASYQRFRQLSERIDAPARWCPGNHDEL
PAMQEAARGSEMMAPVLDVGAWRVIMLDTLVPGSVFGMLRDDQLELLERTLQDAPQRHHL
VCLHHHPVTIGSRWMDSIGLRNRDALFAVLDRFPCVQAVLWGHIHQEFDDQRGDIRLLAT
PSTGVQFAPGSEEFQVDTLAPGYRWLRLHDDGRLDTGVSRVVGMTFKVDHSIKGY
>A0A6S7A2X2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter animicus|TrEMBL
MLIAQITDLHMRTPGDKAYGIIDPAAFLAPAVRALNALTPRPDCVLITGDLTDLGKPIEY
QTLREHLQALEIPYFLLPGNHDDRAQLRAAFPDHAYLQDGGQFVQYAIETYPLRLLALDT
VVPMKSHGELCQTRLDWLAERLAEQPGRPTLVLMHHPPFLTGIEHMDDIGLLAGAPELER
IVARYPNVERVLCGHLHRTIFQRFGGTIASTCPGTAHQLALELGPRPTLQYIMEPPGYQL
HWWQGGNLVTHHAVIGDYPGPYPFG
>A0A812AE85|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Methanoperedenaceae archaeon GB50|TrEMBL
MVKDEKIKIAHVSDLHITGPNFVSQWGENVIDILNSEMPEILIITGDLTDDGYVHEYELA
KTYIDRIKVKNKIVVPGNHDARNEGYIIFEEIFGTRCPYYENEKVVILGIDSSQPDIDDG
HVGRENYGLIREKLSINNKVKILAMHHHLIPIPGTGRERNIPSDAGDVLKICMELGVNFV
FSGHKHLPWTWRLENTYLITAGTATSRRLKGRSYPSFNILEIPAIHADKQDKMAILKEVN
VTNKKFREILRGFRALKNIETPLV
>A0A5C5QNJ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas extremaustralis|TrEMBL
MPSVSTLTPDAPALLVQLSDSHLFGEADTALLGMNTCDSLRRVIELVCAQQPRIDLVLAT
GDLSQDGTLASYQRFRDMTTAIAAPARWIPGNHDEPQVMAHAAMHSDLLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDSQLQLLAQALSEAPNRHHLVCFHHHPVSIGCAWMEPIGLRNPD
ALFAVLDRFPQVKALLWGHVHQEIDLERNGVRLLASPSTCIQFTPGSEDFSVNEQAPGYR
WLRLHADGRLETGVERLAGFAFTVDYGSNGY
>A0A5M9IU11|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas extremaustralis|TrEMBL
MPSVSTLNPDAPMLLVQLSDSHLFAEADAVLLGMNTRDSLQRVIDLVCEQQPRIDLLLAT
GDLSQDGTLASYQQFREMTAPFGVPARWIPGNHDEPQVMAHAAVHSDLLEPVVDIGHWRI
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPNRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVKAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFNVSEEAPGYR
WLRLHADGRLETGVERVKNFAFTVDYGSNGY
>A0A831RFC5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylothermaceae bacterium|TrEMBL
MAMTLELSLPPRAPVKLLQLSDCHFLEQPGDTLMGVDTEQSFHSVLASLRQNPNWPADLI
LLTGDLVQNPTRNAYQRLFRHLRNIDIPWVCLPGNHDDLSLIREILCREKAHCSKRILAG
RWQILCLNSKLPDSHAGHLAAEELDFLAQSLAQNPIPTLVALHHPPLPVGSTWMDTMQLD
NSEQLFSVLNHYPHVRGIIFGHIHQVFEVSHNGIPLWSVPSTCFQFKPKSSDFALDELPP
GWRWLKLQPDGRIDTWVERLDACPPGLDFSQSGY
>A0A5M9IUB9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas extremaustralis|TrEMBL
MAMHTKPQRRTDGLLNPDRRTLLKCSAWAGAGVIWALHGGIPKAFALDAAGNVSDPEALD
STFYFVQISDSHIGFNKEANPEPVKTLQVAIDKVIALPKRPSLILHTGDITHLSKAEEFD
TSAQLLKALPSTVHYVPGEHDTLDAGGGALYLERYGKGTKGNGWYSFDDHGVHFIALVNV
FNFQAGREANLGADQLAWLADDLRAVSSSTPIVVFTHIPLWTIYQPWGWGTEDGDQAIAM
LRKFGSVTVLNGHIHQVIQKVEGNITFHTARGTAYPQPAPGAAPSPGPMTVAADQLRNYL
GVTEVRATQGDHPLALIDSTLV
>A0A2P8APY2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micromonospora sp. MH33|TrEMBL
MLPGNHDNRSAYRKVLLGTDGDAPINQLHRVGDVLFALCDSTIPGRDDGRLAPETLDWLR
GVLAEAEAPVVVGLHHHPIRLHNPLVDSIRLGNADEFAAIVRQAPGVAAVLCGHAHDAAA
GSFAGRPLLAAPGVVSTSRLPWTTTDELTWANTADLTDPPGVMFHVLDDEGTLTTHIRTA
PE
>A0A2T3II62|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium aquimaris|TrEMBL
MQTYSLPQSNPDSVVLLQITDTHLFANGSGSLLGVATKDSFHAVLNGVDTAARHFDAIVA
TGDISQDHTPYSYQRFADGISRWSQPCFWLPGNHDFQPTMQSILPSEQIKPHQQVLVGEH
WQMILLDSQVQGVPHGEVSAAQLALLETALARYPDRYALILLHHHPLEAGSAWLDQHQLH
NNHQFWNVIDKYPQVKAVLCGHIHQNLDRIYHGVRVLATPSTCIQFMPDSDDFALDDNNP
GWRYLELTRDGKIITSVHRVDGDQFKPKLDAEGY
>Q1R6V1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli (strain UTI89 / UPEC)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>G1R1Z1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nomascus leucogenys|TrEMBL
MQGPPAPAPAPGPGSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHLLCFDLENGLSCGR
RALDPQSSPGLGRVMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIV
TPFAQVLASLRTVRSNVAALARLQCLGAAKQGPVGNPSSSNQPPPPAEDTGQKLALETLD
ELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISRTFLDQQT
EVELPKVTTEEAPQPMSRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWG
LDVFKVAELSGNRPLTAIMFSIFQSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNL
SAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQN
LVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGF
IDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSDLTNPERDGPDRFQFEL
TLEEAEEEDEEEEEEEEETALDKEALELPDTELLSPEAGPDPGDLPLDNQRT
>A0A7S7MVB0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. OST1909|TrEMBL
MPSVSNVNPDASALLVQLSDSHLFAEADTALLGMNTRASLQRVIELVREQQPRIDLVLAT
GDLSQDGTLESYQQFRDMTRPIGAPARWIPGNHDEPQVMAQAAVHSDLLEPVVDIGNWRI
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPNRHHLVCLHHHPVSIGCAWMEPIGLRNPE
ALFAVLERFPQVKALLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFQVSEQAPGYR
WLRLHADGRLETGVERLRDFAFTVDYGSNGY
>A0A1B8H1N2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Morganella psychrotolerans|TrEMBL
MEIPLHLTVADGAAVRILQITDTHLFAGETETLLGINTLHSYHAVLDAIKKQQLPADLIV
ATGDLVQDQSIRAYQRFTQGVARLPAPCVWLPGNHDYQPSMAKELADAGINPAKHILLGK
QWQVLLLDSQVQGVPHGELSEYQLAWLDERLAQYRDRHTVVMLHHHPLASGCTWLDQHSL
RNSHELADVLVKYQNIDAILCGHIHQDLDMIWNGMRVLATPSTCVQFKPHCTTFTLDTVA
PGWRYLELTTGELPALKTTVHRLDTDEFSPDLGSEGY
>A0A0S7M5B8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
DQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIASTFLEKQHDLEILS
PLAKEKEKKKRPMSQISGVKKATQSPSLAPACIPRFGVNTPHESMLAKEIEDLNRWGMDI
FKLAEYSGNRPLTVMMYSIFQVGKSYC
>A0A0G3CTA6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pragia fontium|TrEMBL
MESLFQLPLARGTRVRVLQITDTHLFAGMDETLLGVNTLQSYQAVLEAIAEQGHDYQLIV
ATGDLAQDRSLAAYQRFAAGIAHLPAPCVWLPGNHDFQPAMVDAMAAAEILPSKQVLLGD
DWYLILLDSQVLGVPHGELSEYQLNWLDHSLSRYADRHALILLHHHPLASGCTWLDQHSL
RNAHMLAEVLDKHPQAKTLLCGHIHQDLDLDWNGRRVLASPSTCVQFKPHCTNFTIDELA
PGWRYLDLYSDGSIDTTVCRLNSDAFRPDMNSDGY
>A0A7L5RU99|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. ABC1|TrEMBL
MTPGTERDPLLLVQLTDNHLFAEPDGCLLGLPTLDSLRAVVDQVLREQPRIDLLLATGDL
SQDGSEQSYRHLCEQHARIDAPVRWCAGNHDEGEAMARVASAQMLQPVTDLGAWRIILLD
SSVPGSVFGHLPDERLAWLEQALQAAEGRHCLVALHHHPVAIGSQWMDGIGLRNGDALMA
LLARHEAVRVLLWGHVHQAFDQSRDGLRLLASPSTGVQFTPHSADFQVSPQAPGYRWLRL
HGDGRVETGVSRIAQGTFPVDLQGGDY
>A0A3S9W8K5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microbacterium lemovicicum|TrEMBL
MVAASFSLGQHPPARRTIVHLSDTHLLGGDRLLGGVYDTAGHLTRTLDAITRLGIAPDAL
VFTGDLTDVGEPEAYRALRALVEPVAAELAAPLIWVAGNHDERPAMRRELLDGEASEEPV
TGVWDLGGLRLIALDSSVPGWHHGEVDAAQREWLAAELATPAPLGTLLALHHPPLPSHIP
LFDILELRDQPLLADVLAGTDVRGILAGHLHYSTSGTFAGIPVNVSAATCYTMNLQRPPA
EVNGMDAGQSFHLVHVYDETITHAVVPVLDAPTGDFFSEEWVERMAALSPEERLEQFSRK
RR
>A7MJS1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cronobacter sakazakii (strain ATCC BAA-894)|TrEMBL
MESLLNLPVAGGASVRILQITDTHLFAGKNDTLLGVNTWESYQAVLAELHAEQRECDLIV
ATGDLAQDHTPEAYEHFATGIASLPAPCVWLPGNHDFQPAMYSTLQDAGISPAKRVFAGD
NWQVLLLDSQVFGVPHGELSDYQLEWLERMLQAAPERHTLLLLHHHPLPSGCGWLDQHSL
RNAQALDDVLNHYPQVKHLLCGHIHQELDLDWNGRRLMATPSTCVQFKPHCAGFTLDTVA
PGWRWLNLHPDGSLTTEVCRLEGAQFRPDTASEGY
>A0A8E6K740|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Paratyphi B str. CFSAN000542|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A7A2HD32|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQEQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLERLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A2H8TXF4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Melanaphis sacchari|TrEMBL
MWDNCCRRSGSASDLSRDTVDAYSPINRSDSPLTQTTDNFNNFMFGCSKFIQDLHSNYSL
KKILVVTSKDDSVWQSISTTAKNLEWTVNRVTNTEEALECFHKGNGVPTVAFVDCRFQND
KAIDAYQLARSLRSIRKNAHVVLVALVRKSLVLRNEKDVTSILTSGFNKIIVETCNKNVW
IKELQQLEKEDVAMRSILAQQDAVLAALDKTKDLVIITDLKHNIQYMNKSGSVILGYGAE
DMINKPLAIFHQLGDIDQITKKLEKNIEWDGKVSWKCKSGEHVYLHCRASPFRPFGKETT
NYIYIQESIVDIHGFPRGSVPSIRKGSYDLKSINSDGAQSARRQSLAKLHNLPLEAPITK
VISLICTAQENSNDQVVQILDKVVDILRVTELYSSHLKTENIKYDDPVTSDLIGALITQG
PVHVTSTRRSSNDSATVKSQPYGLGVAKMNFMTSVTPQIKELLDMSLYWDFNVFKLEELT
MKRPLVHLGMNLLTHFEVHKTLGCDERTLHAWLTVVESHYHAKNTYHNSTHAADVLQATA
MFLEKDRIKRLLDQLDEACCLIAAITHDIDHPGKSSAFLCNSKNDLAILYNDISVLESHH
AALTFKLTTKDERLNIFKGLEKDTYKVVRQNIIDMILATEMTKHFEHLAKFVSVCNKPST
LDEVPVDGLTPSEVSPETIMPTSAEEVNLVKRMLIKCADVSNPTRPLKMCVEWAKRIAEE
YFNQTDEEKLNHLPVVMPMFDRASCSIPKSQIGFMDYIINDMFETWDSFIDMPEMLYYMR
SNYQYWKDLEEKGTISFNDICKMMTTTLPKIPESGGNH
>A0A4R0DAT2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. ANC 5045|TrEMBL
MTLFSNNHQQRWTIVQISDTHLMNQEDLEFVHMNPERSFHAVMHDIQQQYPQLDAIFHTG
DLAQIPVAETYQRYLQFMQTLNTPHFQIPGNHDDAAVFPFHLQSNQVHAIELGNWSVILL
NTAVKGRIDGWMDAAQLQQLDQLLQQHAQQQVIIACHHHPFDMQSHWIDQHKLKNTEALI
DVLARHNNVKLVLCGHVHQDSLNEWQGIQFYSTPSTCVQFKPHSQHFALGPEAPGYRVLH
LNADGSFSTQVHRVEHVTQQINFEISGY
>A0A1G7VYE6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio xiamenensis|TrEMBL
MKVSSSSTENRSIKLLQITDTHLFAPADGSLLSVNTHDSFLSVVSAIMDRNVAFDAILAT
GDISQDHSEASYQKFEQGIAPLEKPCFWLPGNHDYKPNMGSVLPSKQIQPVEHVLLGEHW
QMVLLDSQVVGVPHGRLSDQQLALLDDKLSAHPQKHTLVLLHHHPLLVGSQWLDQHTLKD
AQDFWQVVEKHSNVKAILCGHVHQDMDKLHHGVRVMATPSTCVQFKPNSNDFALDPQSPG
WRELELFDDGSLATEVNRLESGCFQPDFTSAGY
>A0A5B8RAS1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured organism|TrEMBL
MRIQPVSDLHLETRDGATLEDMVPPADVDLIVLAGDIATGTHGVEAAARLSADRNTPVVY
VLGNHEYYGWHFPELACDCRETARALRERGTGEVHVLEREVLHLGSVRVVGATLWTDYRL
HTHGDVQQVGRNRRIAARQLADHHFIHTRDGHFRPEDAQAAHQHTREWLEAVLAETWDGP
TVVVTHHAPVPQLSHPGYPGDGLAAAFASDLSGLIHMHPPALWISGHTHANADLTIRGTR
FVANQPGYPHEETASIGRAAFTPDKVVVVEPED
>A0A330MFB1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aequorivita sp. CIP111184|TrEMBL
MIQNIKIHNNNFNLHPSGAIFWQNKKMLLIADVHLGKVSHFRKHGAPVPAKAAFENLEKL
TEISNYFQPETICFLGDLFHSKLNEEWQDFEKWVEYIKAEIILISGNHDIIPKYLYEDLG
IKVFDELLLDGFHLTHHPTEIKGTFNFSGHIHPGVRMRGVGRQYLRFACFYKSENQLILP
AFGNFTGKHILKPSESDEVFAIVEGEVICVSK
>A0A8C3RWI2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chelydra serpentina|TrEMBL
MGAPSPMPPASLSPEDACQKLAIETLEELDWCLDQLETLQTRHSVSEMASNKVRDAAAPR
GSLQSPQVLRRHALRSQIQFPLGGEG
>A0A5I2X3Q9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Ank|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A852Q571|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus haemolyticus|TrEMBL
MKNTFVYQTEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENHEFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEN
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTQVKRIQQAEFLPNMQEEGY
>A0A0K2P5U2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cronobacter dublinensis subsp. dublinensis LMG 23823|TrEMBL
MESLLNLPVAGGASVRILQITDTHLFAGKNDTLLGINTWESYQAVLAALHAGQREYDLIV
ATGDLAQDHTPEAYAHFAAGVSTLPAPCVWLPGNHDFQPAMFSTLQDAGISPAKRVFAGD
HWQVLLLDSQVFGVPHGELSDYQLEWLERMLQQAPERHTLLLLHHHPLPSGCGWLDQHSL
RNAQSLDDVLNRYPRVKHLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCAGFTLDTVA
PGWRWLNLHPDGSLTTEVCRLEGVQFRPDTASEGY
>A0A854GQ05|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio vulnificus|TrEMBL
MQHTSSDTLSENSIKLLQITDTHLFASDEGSLLSVKTLQSFQAVVEQVMARHVEFDYLLA
TGDISQDHSAASYQRFADGIAPLEKACFWLPGNHDYKPNMSSVLPSPQITTPEQVELNAH
WQLILLDSQVVGVPHGRLSDQQLSMLEHYLQASSEKNTLILLHHHPLLVGSAWLDQHTLK
DAEAFWQIVERFPMVKGIVCGHVHQDMNVMHNGIRVMATPSTCVQFKPQSDDFALDTVSP
GWRELTLHANGEITTQVQRLASGSFLPDFTSSGY
>A0A6I9NBR0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Notothenia coriiceps|TrEMBL
MSVSPPAALTDPCSEVTCSYGSTCAESSDGVSAKCMCPLGCEGKREQTVCGSDGKDYRNE
CELHQHACKNQKNIRVQYQGNCDPCKDNENSLTTQCRVESITRQSIFSPLPESCPPGGEP
LCASDGHTYPSKCAMEATGRRKGIKVKKIHNGKCRREDDCQEECLFNAVCLVEQLKARCS
CDPIECDGTYKPVCGKDGQTYTNDCMRRKTECLSKTLISIKQQGPCDLSIPSPCLVKVCD
HGAVCVVENDVPVCECPEACPQTSDPVCGSDGHSYGSPCEMRAMGCALQKAIHIQHKGPC
DDSCANCSFGAICDAQSGQCVCASECVTSHQPVCGSDGSTYNSECELHVRACKQQMDLRV
VSQGECKTCGSTVCAWGARCVHNMCECPQCSGEAFSPVCGSDGTTYNNECELRTASCEQK
RKIDAAKPGSCDEDCGSGGSGSGAESCEQDRCRMFGGSWDEDAEDDRCMCDFTCQSVPHN
TVCGSDGKNYSNECQLKKARCEKQEHLLIQNQGACAAISATSLLELSEPQHCSESVYGCC
HDNMTAALGVGLAGCPSTCQCNVYGSYKGTCDPASEQCSCKPGVGGQKCDRCKPGFWNFR
GIVTENIGGCTPCNCDAAGSVRDDCEQMSGLCSCKTGVKGMKCNLCRDGSTNGCDKGPEP
PTSCEELVCSYGATCIEVNDQAHCECPSPDCNEKNKTKVCGSDGVTYADQCQLRTIACRQ
DKDITVQHSGQCTGHVPKARVFMYREDVAPSASLCHNGVQKTSSVSSVGGSRASCVTLAT
GHGQFKRMLNRELSHLSEMSRSGNQVSEYISSTFMDKQNEAEIPSPTLKDKSMSHITGVR
KLCHSSSLSSSSMPRFGVNTDHEDELAKV
>A0A3A2IZV1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylococcales bacterium|TrEMBL
MNELMTDLSILQITDCHILPCLNETFLGINTEHYFQAVIELALTENCPFDLIIVTGDLAQ
NPSQGSYQRILKQIETIETPCICLPGNHDDTQLMQQIFNTPLVSCRKQILLGNWQLIFLN
SQVKGVPSGRLSNQELCFLDDCLSKHPNHHALIAVHHHCLETKSAWMDAMMIENSLELWT
VIGKYPNVKIITTGHIHQLMDIEHEGVRVLGTPSTCFQFKPDSPTFSLDNIASPGYRQMT
LSSDGRFKTLISRLPEPLKDLQIDSLGY
>A0A5P8RYV9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia pestis subsp. pestis bv. Medievalis|TrEMBL
MESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTFHSYRAVLDAIIAEQHPFDLVV
ATGDLAQDHSVAAYQNFAKGISRLPVPCVWLPGNHDFQPAMFDALAEAGIAPSKQVLAGE
HWQILLLDSQVFGVPYGELSDYQLEWMERCLIAYPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAILTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDAVA
PGWRYLDLLPDGGLETEVHRLDSDEFCPDMDSDGY
>A0A7J0AJ94|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MKRLILGILLALPAVCQAGVVSGRVCDSNGIGIGGVPVSDGYEIVTTAYDGRYSIDTKKK
LGLLFISTPSGYEPATCHGNRPDFWRLLTTPADEPETVDFALRKVDDSRFAFLALADNQI
SNRGGDVNCFTSTTVPDVNATVGELRSEGYEPFLILLGDQSHDRFWKDYRYGLPQAYSDI
ERMNARVYSVMGNHDHDPTATNDIDAGAEWRRFIGPEYYSFDKGGVHFVVLDDEEIVENG
PSLSQDGECVYKNKVRKAELEWLAKDLALVDKSTPVVLAMHAPLLAAPGMEEEFRLVNGA
RLASLLAEFDTVEVISGHTHVSYAAQNGNIHETNYGAVCGSWWLNARIDLGNDNNICRDG
TPSGYAVWTRTPEGFSNYFKGTGLDRSKQMRAYDLNCVEIDNAELTESFLPGRKKTNEVL
VNVWSYGPGWKVEMFERGKPLKVERVRSQDPLFLMSCSVPYIAKGKKLTGTVRPLFSWHM
FKAKASKANSPVDIKVTDREGRVYTRRLERPQPMTLDM
>A0A7S4LYN3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia sp. Tan611|TrEMBL
MESLFKLPVASGAKVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAVRAQQREFDLVV
ATGDLAQDHTPEAYRHFADGISQLPAPCVWLPGNHDFQPAMVDALAAAGITPSKHVLLGA
HWQVILLDSQVFGVPHGELSEYQLEWMERCLQAHPDRYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAILLRYPQVNTLLCGHIHQELDLAWQGRRLLASPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVCRLDNDDFRPDMDSDGY
>A0A3M1PEM0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyanobacteria bacterium J069|TrEMBL
MPSSPGLHLVQLTDTHLFANEQGEMKGWQTARSLQAVLQAVAQLQPRPDLLLLTGDLSQD
ETEESYRLLLRLIAPLNIPAVWLPGNHDQAIAPMERVLSVFPASTQKCLQLGGWNLVLLD
SSQFNQVSGWLADDSLAWLDQQLCQFADLPTLVALHHPPLAIGSAWMDAIGLQNREALLA
TLDRHPQVKLVVFGHIHQAFEQERQGVRYWGTPSTCVQFSPNVDEFAIDSAQQPGFRQIT
LYLDGGYDTQVVRVAVAASSDAVPSG
>A0A735P2P5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. houtenae serovar 16:z4,z32:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A8C7WYX0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oryzias sinensis|TrEMBL
LDRTNMVEGLSVSRVLYMLSKEQLLFFCLSFDVENGLSAGRGSPIDAQVNPGSGLVLQAN
FPHSQRRESFLYRSDSDFDLSPKGPTRNPSSASDLHSEDMIVTPFAQVLASLRTVRNNFA
TITGQQDRTVSK
>A0A8C0CNZ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Balaenoptera musculus|TrEMBL
AFQGSKSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKS
MSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINK
ATLTG
>A0A8E0KCE6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O119:H4 str. 03-3458|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A6M1YL62|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chlamydiae bacterium|TrEMBL
MRIFAISDLHLSLSCPEKDMSVFGPNWEDYQEKIKTHWQSIVKDEDLVLIAGDISWAMRL
DQACIDLEFIHSLNGSKVISKGNHDYWWSSLTKVKKILPSSIQAVHHNAIDIDNVSICAT
RFGDSLDFNFDSIVDVNPSQIKQQDPKEKEKIYIRELNRLEIALKELNQSAAIKIAMVHY
PPISLDLKDNPATRLLEKYQVNFCVFGHLHNVKKGTYFGTKNNVHYMFTSCDYLNFTPIL
ITT
>A0A6M2A9K7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chlamydiae bacterium|TrEMBL
MSVFAIADLHLSFGVPEKTMEAFGLVWKHYAEKIESAWREFITEEDLVLVAGDISWAMSL
EKAQIDLEWIGNLPGTKVMIKGNHDYWWSSLAKVQTILPPSCHLIQNNAFSWKDCTIGGA
RLWDTDEYDFSAYIDFQETNVSPSEEPKPTPAKIFNRELNRLELSLQALDPNATHRLVMT
HYPPISSSLASSKVSALLEKYRIDICVFGHLHNVKPKALPFGETRGVAYYLTSCDYLDFK
PIKILE
>A0A5J4E0B6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium MnTg02|TrEMBL
MFKLAHISDIHLTPLPRPNLSELAGKRLTGYLNWLRHRKAVHQRAVLNDLIADMQAQAPD
HIAVVGDLVNLSLPEEFQAAQNWLEALGDPEKISVVPGNHDAYVTSRSEPGIDRWRAYMN
SNAEGARYKATASDRFPYVRIFGPIALIGLSTAIPTPPFQAFGTLGGQQRRALASTLAQL
AEQNLFRIVLIHHAPLEGQVSRRRSLRDSVELSEILRKFGAELVVHGHNHQSSLHHLETA
NGLIPICGVPSASSSGAHKHQPAAYNLYQISKTGTGWRCEVESRGFHQPTSTTPNGEIGE
LARTILSASPDRDR
>A0A8J6BFB7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Eleutherodactylus coqui|TrEMBL
EDAVQKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSETSRSGNQV
SEYISSTFLGKNTYMTF
>A0A7X5ZAA6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas grimontii|TrEMBL
MPSVSTLNPDAPALLVQLSDSHLFAEADGTLLGMNTCESLQRVIELVRAQQPRIDLLLAT
GDLSQDGTLESYQQFRDMTRQIDAPARWIPGNHDEPQIMAHAAAHSDLLEPVVDVGNWRI
TLLDSAVPGSVPGYLQDSQLQLLAQALSEAPNRHHLVCFHHHPVPIGCAWMEPIGLRNPD
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERLVGFAFTVDYGSNGY
>A0A221K6B4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sulfitobacter pseudonitzschiae|TrEMBL
MTRFIHLTDLHVSHPDAGDPSANVPQNAPMLEQVVGLINAMERQPDFVVASGDLTNMGDP
DSYAMLKDILKPLAPPLVMALGNHDKREGFHKVFEGTSSDAPFFNDQVLGGLHVITLDTL
VPGHVAGTLCDAQFDYLAAALSRHADLPKLIVMHHPPRVDADGLPWGSIDMDSTNRLADL
LRGQHIAGILSGHIHINQVNHWNGIPLVVSMGLNSSVDLLETNDLRLVEGRGFGVCDWRA
TGLSVSFVPLTPTPRELGVIDRARLLAFT
>A0A5E4LX36|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MVQTRPVQSQPALILEEEKNRYLVVTDLHIGFENAFLSNEIHVEPKELVQEAVDSLLSII
ESEKPNVLVLLGDVKSGIDFISKTEWQAVPLFFEIGKKIETIIIPGNHDSNIQKLLPDGV
TLVSSSGLVIGDTLLTHGHTLPSENLSQINKIVMGHVHPVFFQEGSVIDGQRVWVSIRAE
KNQLFPSSRGTLEIIILPAFNKYFYATHKKYYKKSISPILQSIKNFQSAKIVTLDGSIIG
TESMLENVI
>A0A5E4JVY3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MVRIFAAGDFHGDKQAARRLAERAVTEKADIIVLNGDIVEEDNPDGIVCYFARTGKPVIL
VPGNHDWFATDFLAAKYNIQNLHNKSMSVGNIAIVGSGSNMAMMSEKDIYEGIRRLKTAQ
KTLLVSHVHPSGTLMETFSQFVKGSVGLRKAIEATNPAVVLCGHVHEAEGIEEMIGNTLV
VNVGKKGRLIEF
>A0A8C1DLQ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyprinus carpio|TrEMBL
ISQGFDVENGLSVGRSPLESQASPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKAMSR
NSSTASELHGEDMIVTPFAQILASLRTVRSNFAVLTHQQDRVLSKRPTGSNPPSMCKTSL
PG
>A0A0T9REQ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia massiliensis|TrEMBL
MESLFKLPMASGAKVRILQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGIARLPAPCLWLPGNHDFQPAMVDALADAGIAPSKQVLVGD
NWQILLLDSQVFGVPYGELSDYQLAWMERCLMAYPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTIDTVA
PGWRYLDLLPNGILETEVRRLASDEFSPDMDADGY
>A0A6P1V205|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella michiganensis|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYRAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFTAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQVLLMDSQVFGVPHGELSDFQLEWLEQKLTEVPQRYTLLLLHHHPLPSGCSWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A8D0EKF3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Strix occidentalis caurina|TrEMBL
LQGTFTHGQRRESFLYRSDSDYDLSPKAMSRNSSIASDLHGEDMIVTPFAQVGASSVRHS
HLLGLGAPRPGPCAQRVPLAEDAHQKLSRETLEELDWCLDQLETLQTRHSVSEMASNKFR
RMLNRELTHLSETSRSGNQVSEYISRTFLDKQHEVEIPSALAKDKEKERRKRPMSQISGV
RKLTHGSSLAAAGIPRFGVRTDQEELLAKELEDTNKWGLNVFKVAEYSGNRPLTVIMYSI
FQERDLMKTFRIPVNTFITYMLTLEDHYHADVAYHNNIHAADVAQSTHVLLSTPALEVSP
DHGCHLRQHSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMAIDM
VLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLE
LYRQWTDRIMVEFFRQGDREREKGMEISPMCDKHTASVEKSQVGFIDFIAHPLWETWADL
VHPDAQEILDTLEDNREWYQSMIPRSPSPPPEGPAVSPGTTDKFQFELTLEEEEEGELDT
EPEGAESPLDEDNSGRCFPSPSDCPLLPP
>A0A1X1DL36|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mixta gaviniae|TrEMBL
MDSLLKLPVVSGASIRILQITDTHLFSGRHETLLGVNTWASFNAVLDAIEAEQQPIDLII
ATGDLAQDHTPEAYQHFAEGIGRLPAPCVWLPGNHDFQPAMFGTLARSGIAEAKQVFIGE
RWQLLLLDSQVAGVPHGMLSDYQLDWLEKTLAQTADRHTLILLHHHPLPSGCSWLDQHSL
RNPHALEAVLQPYPLANTLICGHIHQEMDVEWHGRRLLATPSTCVQFKPHCTNFTIDAVA
PGWRWLELDENGAVQTRVQRLASRAFTPDLDSEGY
>A0A1A9FET6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lelliottia amnigena|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQSVLDAIHAQQRACDLIV
ATGDLAQDQSAAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSALQDAGISPAKRVFVGE
HWQILLLDTQVFGVPHGELSDFQLEWLEQKLIAEPERQTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLMKYPNVNTLLCGHIHQEQDLEWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELYPDGSLSTEVCRLEGAQFNPDTASEGY
>A0A2N7IQU4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. 10N.261.52.A1|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGER
WQMIMLDSQVVGVPHGRLSDQQLDLLEQKLAEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHSNVKAVLCGHVHQDMNREHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPNGQFLPDFEAAGY
>A0A2K6FGN9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Propithecus coquereli|TrEMBL
AFQGNRSFDVDNGTSVGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKS
MSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINK
ATITG
>A0A653X9Z6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arthrobacter sp. 9V|TrEMBL
MELIEAEYPKPGHVLLHLSDLHLVGGPGTLHGSVDSAARLQEICEQILASRIRPEAIIFT
GDLADKGELEAYEQLREMIEPLCASLGAKAIWAMGNHDNRANFRSAFADASAASKPQDPV
DRSYFVNGLRIITLDTTVPGHHYGQLSESQLEWLESELATPAPDGTILALHHPPVPCVQD
LAVLVELRGQAALAAVVRNTDVRAILGGHLHYSTTASFAGIPVSVASATCYTQDLAVRAG
GQRGRDGAQSYNMIHVYEHTIVHSVVPMSGGVTVGEPLDAAEVQRRLTAAGIRIPHESRV
GAHTSPGTHTSSLPLVSSGPTSPKAP
>A0A485PB71|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lynx pardinus|TrEMBL
MPLVDFFCETCSKPWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVE
IPSPTMKDREKQPAPRQRPSQQPPPPGPQFQPMSQITGVKKLMHSSSLSDSSIPRFGVKT
NQEELLAQELENLNKWGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFRIPVDTMVTYM
LTLEDHYHPDVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPADSELALMYNDESVLENHHLAVGF
KLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVL
LLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMC
DKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQSPSPPP
EEEPRGPGHPPPPDKFQFELTLEEEDEEEVSTAPGAFTVQGLSVAQDASPAEELLEVDGQ
DMPTEVKVQEPCCTQQADSAGSVAAGKDKATSPDASVDAVGRSSPLALSAGSPLPPALRT
PPPPEDTPGLPGLPSTAAEAGAQKEHQAAKRACSACTGTSGEDPPPLPAPGGWGSAGGPT
>A0A3S4QRA6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aggregatibacter aphrophilus ATCC 33389|TrEMBL
MLNTYQYNTQQEVFRIVQITDPHLFKDTNGELLGINTQASFSQVLTEIQQQQYAYDLVLA
TGDLVQDSSDEGYLHFCEGVKALEKMVFWIPGNHDFQPKMFDLLTKDNISAKKHILLGDR
WQILLLDSQISGVPHGQLGEYQLDWLLAKLKEYPQRYSLVVLHHHILSTHSAWLDQHNLR
NAHELAYILAPFSNVKGILHGHIHQQVDGEWHGYKVMATPSTGIQFKPDSNTFALDTVQP
GWREIELYADGRIETRVKRIQHKTFLPNLQEEGY
>A0A7U8X636|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli FVEC1302|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7X8YIM3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio aestuarianus subsp. francensis|TrEMBL
MNASPTLDNTDSIKLLQITDTHLFAPEDGSLLSVNTVDSFNAVVTEICAQNVVYDAVVAT
GDISQDHSAESYLRFADGIAALDKTCFWLPGNHDFKPNMGSVFPSAQIQQPEHVLLGKRW
QMILLDSQVVGVPHGRLSDQQLALLDEQLSAYPQRHTLVLLHHHPLLVGSAWLDQHTLKD
SDAFWNVVTQHHNVKAVVCGHVHQNMDKLHHGVRVMATPSTCIQFKPNSDDFALDRTSPG
WREIELLPDGQIKTQVKRLANGVFQPDFNANGY
>A0A1B6DFI7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clastoptera arizonana|TrEMBL
RTDVLVRDEDCDTQVNELAAESNCEPLCHRLQQIKTNSPKQHAFRVLLVFAKDDSACSTL
SGASEHLGFSREVASTLEQALELYQAHSSPPQIVFIDMRFSWFHGEKICRSLRAVKKSNH
VIFVAICKKNVVDKDEKELRSALKLGFNRVLVEPLSITQCVCELVQLAHGQLDLHSILAQ
NEAIYLALDKSRDLVLVTDSLHVIQYVNRTWCQVLGYKSEDLIGRSLHSFHQLGNMDPVT
RQLEKGFDWEGKISWRSKSGENITLQCRAMPYQAIGSEPTHYVYVQDNPLENHIYPRGSI
PSIRKGSYDLKSINSEGAQSARRQSLAKLHNLPLEAPITRVISLICAAQENSTGQVVQIL
DKVVDILRTTELYSSHLKADNLRCEDPVTSDLIGALITQGPVPVSTTRRSSNDSAAVKAQ
QAGLSGNKPIFSMSASPQLKELLDTSLQWDFNIFKLEEITGKRPLVYLGMNLLMHFDVHK
TLGCDEKTLYNWLTVIERNYHLSNTYHNSTHAADVLQAMAGFLEKERIKRLVDELDEACC
LIAAATHDIDHPGKSSAFLCNAGNELALLYNDVSVLESHHAALTFKLTLRDDRVNIFKGL
ERDTYKVARQSIIDMILATEMTKHFEHLAKFVSVFNKPSPTSEDGNCDNRFFDSSSSSDT
EIASMVPTFSQHRVDVTSGVFQNHMSPSDCGGDISMLTNADEVNLVKRMMIKCADVSNPT
RPLKMCVEWARRIAEEYFTQTDEEKANHLPVVMPMFDRTSCSIPKSQMGFVDFIINDMFE
AWDAFIDMPEMLYHLRSNYQYWKDLEEKGVTSLGDISLKQPCSLSPIPNLPNIPEKHSNA
Y
>A0A2S9YJD6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enhygromyxa salina|TrEMBL
MDALRDRAGVVGVFDDTLATTVIPDEPLCWLHISDLHVVGNDWQQDHVLRAFLRDLPRLL
EQAGPAPQLVFVTGDVARHGARTDYDGAHAFLAALCEQLGLDWRQRLFVVPGNHDVDRKA
ISKTVARYDRAFDELDEDEFRTAIGVLIDDADDLALHGRRLGNWCEFTAKLQGPARRVSI
DRPFRSDIVEVGGVTVGVASLCSAWLSGPDDARGRLVVGQRQIQLLVDELAAGGAQLRVA
LLHHPLDWLHEVEAKYLRALLRNEFDVMLHGHVHHPEAGAFVQGRQGTLEIGGGALYAGL
GEDRFHGFTIVQVDADAGRLHVDAFTWTTRSGFWHRDAGFHRDAPDGRMTLELAFPRLGK
VATEKPAGSPDPLVARLRRAVIDVHGEQTFVGLADGAPKPVASIHDIFVPLELRRRDAAE
ANERLSLEVLVPGWLRPAAEGKRAARAVILGDPGSGKSTLARYLAMRVAESEAPVVPLLL
TVRDWVMGGGEEGMLDQARRYAASVLEIRTSVETLEQLCERGQAVLIVDGVDECSETLRV
GLRDRLHGVASRYPLMPVLVTSRILGYDEAPLNATPFQHFVLEPFDDEQLRQFIERWYVV
AESKNPVERQRKQAQLWSALEAEPRAKQMARTPLLATLLALVHFHRAQLPGERAQLYAVC
IDTLVVTWPAARKRSLPELAGHRQLPMLEKLAFWMQSQRPSNFDTREQQLGVVVTRRQLD
DQLEAQLADHAPESNEGWRRDLAHKWRRWLVADSGLLQESQRDRYSFVHLSLMEHLAGQA
MLRQQGRKGNDAITRFVVEHHKWAAWRETLLLALGSRAEDRELGSAIMEAVTEINPFQFP
SALFLLGVLREEIDVGERLCGRALDVVAALLSEYGPYTGSEVRAHIANILRFTHRHSDTV
RRWIEAGLAERSDRALVGLLSLVPTGLPVVHALDCREEQDLGLVAFLDLDRGEWSTWARG
KAKRSTLLTWVMGMPFARAQRRLFGNPTQLDSCLWVAWLLHQMTWVWDRVQRVVADSDAL
PRTLVTGTDMVHLAPSIRITCGAELSERGPAAGDSWQGDPVGAGYHAHFGVAFSTQIGRD
LANLTIELRSASMSYIEARTEIANTLVRACLPPASPAWKAVLEALAGLVGNYATADEASR
MARIRAANRALNTGFDLFVDTHNWDTPTPEKHALQLALGLAQYQTSWSWPTSNYWPTWFA
GAPPEHWLPAHVWHLCRAVQEPDNPDHQSHAAACLARGDFPEFVDLLRQFELGPPDPEFL
AHFSGPPIELPDLPDPPPRS
>A0A8J6S1Y0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trichocoleus sp. FACHB-90|TrEMBL
MIPAKPLAIAQITDIHLFADTKKELLGLPTEKSFHAVLEQLQKLLPQLDMLLLTGDLSQD
GKAESYQRLAELLSPLSIPTYWAPGNHDQPLVMQQVLKEAPISPEKSFAAGGWQFLLLDS
HVSGCVHGKLSSESLVWLDTQLKLASDRPTLIGFHHPPFLVDSDWLDGSTLQNPEELFAV
IDRHPQVKLVIFGHIHQEFYQRRGGVHYLGSPSTSIQFEPHSHNFSLDEVEPGFRLLNLY
PDGSFETRVQRVTYVHELDLAATGY
>A0A7C1Y7I4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acidiferrobacteraceae bacterium|TrEMBL
MDFKKSDTVDTPIRVLQITDFHLFEAPHQTLMGVDTQKSFETVLGWAREDEWPPDLVLAT
GDLAQDGGEKTYRRLQSNFASFMVPTYWIPGNHDNPTIMQDTLIGGQVSADKRVKLGAWQ
IILLDSTVFGNVHGELCESELKKLDDWLTELPDKYAMVCLHHHPIAMGSDWIEPIGLKNS
EDLFVVLDRHPQVKALVWGHVHQKLAQQRNGVKLLSSPSTCFQFKPHSSDFTVDTALPGY
RRLDLYADGRIETRVERLEDYDLSLDPNSPGY
>A0A4U6QRE7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter sp. PJ-16|TrEMBL
MTENDNQRALRVLQLTDPHLMSDPGGELLGVNTRDSLDAVIEQVLHDHGQPDLILATGDI
AQDATEEAYRLFGDKLKVFRCPSAWMAGNHDDSPLLARIASESQADRRHIIQGGWQFILL
DTSVPGKVFGELAESELAFLEEALSQNPGTPALVALHHHPIDIDTEWMSPIGLRNRDAFW
QVIDRFSQVKIVLWGHIHQELEQTRKGVHLLATPSTCIQFTAGSVEFSVEDKAPGYRWFE
LLPSGEFSTEVSRATDFVFDLDSNSTGY
>A0A2T3NIL3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium sanctipauli|TrEMBL
MQNYTLPQANPDSVVLLQITDTHLFADECGSLLGVATKDSFHAVLDAVDVAARPFEAIVA
TGDISQDHTAESYQRFCDGIARWSQPCFWLPGNHDYQPSMQAVLPSPQIKPCHQVMAGDH
WQVILLDSQVQGVPHGELSEQQLAMLDQALAAHPERHALVLLHHHPLPAGSTWLDQHQLH
NAEAFWQVVDKYPQVKAILCGHIHQELDRIYHGVRVLATPSTCIQFQPDSHDFALDRQNP
GWRMLELTAQGQLLTQVYRIEGSQFTPQFDSAGY
>A0A5E6VNA3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPQPNHPHAPINVVQLTDAHLFADPAGTLLGLNTRGSLQQVIDQVHREQPAIDLLLCTGD
LSQDASATAYRAFAEMTATLRAPARWLPGNHDQARVMAEVAQGTDLLQSVTDVGNWRIIM
LDSAVVGATHGLLAPAQLAVLDQALNSAPQRHCLICCHHQPVDIGCAWMAPIGLRNSDEL
LQRVQAHPQVRAVLWGHVHQAFEQTRDGVRYMATPSTCIQFAPGSVDFKVSEELPGYRWL
RLHADGQLETGVERALDYVLQLDFNSPGY
>A0A5E7BR18|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEAGGTLLGMNTRDSLQKVIELVLKQQPQIDLMLAT
GDISQDGTLESYQLFREMTAQIDAPARWIPGNHDEPMIMAEAAVQSALLESVVDLGNWRV
TMLDSAVPGSVPGYLQDDQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQARAVLWGHVHQEIDRERNGVRLMASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGGLETGVERVTGFDFTVDYGSNGY
>A0A4Y9TLC0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTVNPDASALLVQLSDSHLFAEADVTLLGMNTRESLRRVIELARAQQPQVDLVLAT
GDLSQDGTLESYQQFRQMTAPIGAPARWIPGNHDEPQVMVRAAEHSDFLEPVVDIGHWRV
ILLDSAVPGSVPGYLQDQQLQLLAQALSEAPNRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVKAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERLVGFAFTVDYGSNGY
>H3A4X1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Latimeria chalumnae|TrEMBL
IFLRLFQRSLLRNKRRFLPLAECTGFDVENGPSPGRSPIDMQASPGLVLHPSFPQSQRRE
SFLYRSDSDYDMSPKTMSRNSSITSEVHAEDLIVTPFAQVLASLRSVRNNFSILANVPS
>A0A231GV06|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nocardia cerradoensis|TrEMBL
MLVAHLSDPHLRSDALASGPAAALHTALGRVLAVDPRPDCVVITGDLVEFGHDNAYDQLR
ELTVRFPIPVYLVAGNHDDPAVIRKIFADTSLLGGAQDTHYVVDHDRFSVIVLDSKHPGG
PGGLLGDQQLAWLDESLSTRREVPVFVALHHPPVAVGIPFLDGMRLADGAKLAEVVSRYP
NVARVLAGHVHRPIHAPFAGTSVSVAPSTFRQTSLTLRADRQIGYLDDPTGFLLHVGTED
GIATHTVPVSGATALIGAL
>A0A389M8A5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacterales bacterium|TrEMBL
MESLFKLSLVNGANVRILQITDTHLFAGEKETLLGVNTFRSYRAVLDAIKAQKRDVDFIA
ATGDLAQDQSLEAYRHFARGINELPAPCVWLPGNHDFQPAMVDALQEAGILPSKQVLLGD
HWQVLLLDTQVFGVPHGHVSEYQLEWMERCLDEYPDRFTLIMLHHHPLPSGCTWLDQHSL
RNAHMLANVLTRYPKVNTLLCGHIHQELDLDWYGKRLYATPSTCVQFKPHCTNFTIDTAA
PGWRYLDLCPDGRVETQVFRLDTDEFSPDTDSDGYE
>V9LA21|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Callorhinchus milii|TrEMBL
REKKRKERKERKEARERGSEWPRMKEKLSVSLSLPVGSERESGELGSADGRPGYLFAEES
YQKVAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSQF
ISDTFLDKQNDVEMPSPTQKERDKKKKQQLMTQISGVRKLRHSSSLTNSSLPRFAVNTEH
EDSLSKELEDLNKWGLNIFRLADYSSDRPLTCIMYAIFQERDLLKTFRIPVDTFVTYMMT
LEDHYHPDVAYHNSLHAADVAQSTHILLSTPALDAVFTDLEILAAIFAAA
>A0A366AWL8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio paracholerae|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFAAEDGCLLSVNTADSFAAVVAAIGGEQIEFDAILATG
DISQDHTPESYQRFVRGIQPLQKACYWLPGNHDYKPSMHSVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEYPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRIHLGARVMASPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A6S7CUU8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter anxifer|TrEMBL
MTNQRFSRQPLGARLFSFAVVADTHVNESEDSCASPFATNARANARARHVFADIARLDPA
PAFAIHLGDIVHPVPSMPSFDEAADRFKAIAGQIDMPLHLVPGNHDVGDKRIDWMPADIV
CDDYLDKYRQVFGPDYYAVDHGGARFLFLNSLLFNSGLAADAAQRAWIDEQLAGAPGRVF
VSLHYPPYLHDAGERGSYDNIDEPGRGWLLSRLADPRVEAVFAGHVHNFWYDVIGQAEIY
MLPSTAFLRHDFSEFYRVPPADEFGRGDVEKFGYFIVDVHEQGHVAKLIRTHGAMRREAE
SGEPAARTLPTVHTKTSACDGIAVEMRHPWAEIVEIPCTGGVQEFGRKLARNDYPLMSMW
EMGLRTLKIPVQDLRDEQTLRRARLMSDVGHRFVLTSLGLPGAQMLAQARQHGVNIAAIE
INLNAQALQEAGAALRGLREHTDARLIYCKIRTGDDDAHYDGKHYSHFVNTGLRAAELET
AQSALLPHFAQKNLDGFTVRLDWGADLIATHQLLAMRARDWGVSVNVGVKLADRLAAANS
DDTAIAALVAEACLAARTTNAVSYSFDTYMDVDRGYFPRNGLIDRRYDPRPAGLALAALN
ALFEGRETGSGSIERIAGEAGARLSRYRAGGQTYELAYGPAAALRRQVEAEAFKRVIDLP
AQRVLEGRDGWTDYARLHLPGQALLLIHRG
>A0A433SDS2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Saezia sanguinis|TrEMBL
MPLFFFYVALVYCCINFWIIWWFWRALRGSGRVRVITCLVLLFIAACFPFGYLSSSASPW
AMTLLRIGAIWIGVFIYVFLMVLVADGVVIIRRLFRASSQNYFQNSSQKHRQRPRYLACM
AVVVLTVMLGAAGWINAAYPVVREFDVTVPTQQPELQGKTLTIAALSDLHLGRTLPAARL
SRAMGLIAPHQPDAVFFLGDVLDDHILLDLDAMRDAIAQVQPPLGVWGILGNHEYISGQA
SESQEILEQVGIRILRDDWAVLENQLLLVGRDDYSKPRFTHAERAPLAEVLEAVPSAHRQ
LPLIVLDHQPQHLDEAERAGTALQLSGHTHNGQIWPVNLIVARVFENPYGYSTRSETHYL
VSAGAGTWGPPMRNTARPDVLIVRLRFN
>A0A3S6F0H8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia entomophaga|TrEMBL
MESLFELPMASGARVRILQITDTHLFAGEDETLLGVNTGRSYRAVLDAIIAEKYSYDLIV
ATGDLAQDQSIAAYQHFAQGIARLSAPCLWLPGNHDFQPAMVDVLAAANIAPSKQAFVGD
NWQILLLDSQVFGVPYGELSEHQLEWMERCLQAHPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLADVLIRYPRVTTLLCGHIHQELDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPGGTLETEVRRLDSDEFNPNMDADGY
>A0A6P1LW02|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter dispersus|TrEMBL
MTFQVSSLSQQDFVMIQITDTHLLEYPHLEFVGMQPEQSFHAVIDLMRQQHPHIDLIVHT
GDLAQSPTPLTYKRYVQHMQSLGIPFFQTPGNHDDVTHFPFHEADQTQPTIIELGQWCII
LLNSAQPKRIDGKIAEVQLQQLTQLLTQHHDRHVIIACHHHPFAMQSAWIDQHKLKNSSD
LLETIQPFTNVKAIVCGHVHQDSINTWQGVEFLSTPSTCIQFKPKSDKFALDEEHPGYRF
IRLKANGELETQVYRLPTSQRMNSSEVLGYD
>A0A7T1AMH1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Atribacter laminatus|TrEMBL
MKPFFVNKKFCLALLMGMLIFSLPGYSKATVKDQQQPTGYPIASDVQTTTQRTIVPEPTP
TTAINLWEISKYSQYGYGNWTYGPGLPYNKRLDLMPASYSGSAVTRIMKLLNFFTISDIH
ITDKESPNQLIYIQRLHPNLPIGTSLCSGVMLYTTHVLDAAIQTVNALHKQNPLDFGISL
GDAINSTQYNELRWYIDVIDGKVITPSSGAHLGAETIDYQKPYQAAGLDKSIPWYQTLGN
HDHFWMGSIPVDYSLRKDLRQSYVADEVFATGDVLRDPREINNRDYYVGVFDGSTPYGNI
KYAGPVKDFKTPPKVAADPDRRSLLRTEWMQEFFNTSTLPIGHGFNLTDVENGFACYSFV
PKSNIPLKVIVLDNTQQEDSGSVDIHGHGFLDSARWDWLKKELADGSAAGQLMIIAAHVP
IGVEVTAPNSEMGWWTDPQNAVTLPDLIAELQSHPNFIMWIAGHRHLNTVKAFVSPDPVG
APEKGFWQVETSSLRDFPQQFRTFEIYLNSDATISIMITNVDPAVLEGTPAATSRKYAIA
AAQIAGTWDTLTNWNPTNDPTVELMPTGSYNAELVTPLSPAMRKMLQNIETTQR
>A0A443UUC9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAEHRDCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLAKYPRVKHLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLAGAEFRPDTASEGY
>A0A6P4EPU8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila rhopaloa|TrEMBL
MRNCLPKFSKVFRRKSSAKSSASAGRENPSNDPDSDTEPYGIAAAPAFISTSHQCGDNRN
ERPLADDDSGRSRLISAAHLDLDLDSDSKSPAMATTTTMTTNGGIRPKSEGSRPEMKVET
ISAAAAPTPGPVAISLPFVGRNSSKTPEEMELEYEANVEAESRDIMTPLRRNTRPLSVAF
AGGRNALQPEIVEAIRSLDVPALLLNNLSLEGVRDLGGDSGGCTAAEISPGHQDLEDSVV
LRRKANCLERRAHSLYERRLPKVPKLHLLVAGGGGGGGGKKPTEEEEELRTFQRNLMDLK
YPTVLPPNPPLKALLVFHKSDSICEAITAACQRHQLDVTLVKSKEEALDTLQKSYATAQC
YHLIIIDARSTKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRC
VAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRA
TERLLNMRLDEIISKQLEDIFVSDLSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVP
VACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRT
SLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDD
PIATDLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKSNPIIMELLDESLSW
DFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNS
THAADVMQATGAFITQLTNKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALA
VLYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEH
LAKFVSVFGGEEPREHNCQTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYF
MQTDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQIN
YSQWKKYDEQGVNTLAEIMAKQPPVGKMANSK
>A0A090RG01|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. C7|TrEMBL
MKVSSVISDSLEVVKLLQITDTHLFSDEEGALLNVNTRDSFQAVVEMIQAESVEFDAIVA
TGDISQDHSAHSYQRFLDGIAPLVKPCFWLPGNHDFQPSMGEVLPSNQVQAVEHTLLGKH
WQVVVLDSQVVGKPHGRLSDQQLDLLDSKLSEHSARHTLVLLHHHPVLVGSAWLDQHTLK
DSDDFWSVVEKHQNVKAVLCGHVHQDFDHKRGDVRVMATPSTCVQFKPRSTDFALDNQAP
GWRELSLHACGKVETRVKRLNSTKFMPDFASGGY
>A0A635H7T6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Kentucky|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFLPDTASEGY
>A0A1Q9N5Y6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Odinarchaeota archaeon (strain LCB_4)|TrEMBL
MKIVKSKNYSVFKLKIIAISDIHGNIGVIEKLVEALKQLGGNPDLIIIAGDITHFGGLND
ALDVFKILSRIESKRLFFIPGNCDSPELEKFESDGVVFNIHMETAEYLGYTFIGLGGSSK
TPFHTLYEFSEEEIGNMLEKLSLKVYDAAKLITVTHDPPYNTLIDLNKRGVHVGSRKIRD
FILKKRHFIHISGHIHEARGKDLLGGTILVNPGNASSGYYSVIEIKDWRVNVDFANVFA
>A0A8D2PCV7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Zosterops lateralis melanops|TrEMBL
VPNPGGPMVMSPMMSPMSPVSQMSPMSPLSPVSPVSPEDPSPLALETLQELDWCLEQLES
LETHRAVSGMASDKVGTLGTLGTPLGTLGTLGTHRVVSGMASDKVGTLGTLGTLGTLRDT
GDIGDTGDTEGTLGTLGGH
>A0A7W4KH51|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. 0.2392|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLAKFPNVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADSRFQPDTASEGY
>A0A8D2P6T5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Zosterops lateralis melanops|TrEMBL
CFHLFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSR
NSSIAIFLFQVLASLRTVRNNFAALTNLQDRAPSKRSPMCSQPSINKATITGKNSLFLKN
I
>A0A826L1P0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O6|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>E0LYA8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. aB|TrEMBL
MDSLLTLPAANGSEIRILQITDTHLFAGKHESLLGVNTWSSYDAVLDAIIAQHRDYDLII
ATGDLAQDHSIEAYQHFAEGISRLPRPCVWLPGNHDFQPAMVDTLAAAHINAHKQVLVGE
QWQIVLLDSQVYGVPHGMLSDYQLEWLDNALARFPQRHTLVMLHHHPLASGCTWLDQHSL
RNSHQLDAVLQRYPLARTLVCGHIHQELDMEWHGRRVLATPSTCVQFKPHCTSFAIDTVA
PGWRWFTLHPDGGLETEVNRLDTDAFRPDLDSEGY
>A0A644TWN8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MFVAHISDPHVGAGRSLAFNVSDGALLLEKTVSHIAALPQLPDCLVLSGDISVNGQPGGY
VIAAEALSALPMPVYVLPGNHDKRENLVAGLGQYCPADAAVTPYLCYTVEDFPLRLVFFD
GTRSGSHSGHFDAPVAAWLEKTLAAQPGRPTLVFTHHPPFITALGVMDEPYENAGSLASI
LEKFPNVRLCCGHLHRYMFTMWHGVAALTAPPVCMHIVPDFCATGGDDFTDEAPAFLLHH
FVDGRVNTHYCRVPGEFAERGPFSFSHPPKLG
>A0A4Q7HA47|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas moorei|TrEMBL
MPSVSTLSAADPALLVQISDSHLFAEADGTLLGMNTRDSLQRVIELVRQQQPQIDLILAT
GDLSQDGTLESYQRFRDLTGQLGAPARWIPGNHDEPLIMAEAAVQSALLESVVDIGNWRV
TLLDSAVPGSVPGYLQDEQLQLLASSLSETPERHHLVCFHHHPVSIDCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEVDQWRNDVRLIASPSTCIQFEPGSDDFMVGEQAPGYR
WLRLLPDGQLETGVERVTGFDFQIDYSSNGY
>A0A644VID2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MRIINFPLLLIALMLIFTHCTKTDPVVLNPFDIIFDSSNDSRDKIVVISDLHLGNDLTYS
ENVKHLERLEEFLNEVRSSATVKELVIGGDMFDDWYIPTRTDTYGGGSQADFIRKTVAAN
QGVFDALNGIIKDGKIKLTYIPGNHDMGFLPENVNIALPGVNQARDKGDKYGVGTYYPED
YPQIAIEHGHRYDFFCAITPGANESEAPGTFLPPGYFFARIAANSFTNPTTKEAATKVPD
VKLNHPGDSEQKSKHIYYKLWKNVIENLIYVKDSFSEPIIKTNVGGFTKTYSINDIMPRN
SETDGSIQMNLYNGLFTQDNWDARERYNNVPKMTNIDSAIVGSLVTEFIDLQAERQYFKN
SESNVRVVIFGHTHLPKINTHTNRKGEECLYVNSGTWEDEKTRDKNAAIDQDALKMDFVI
ISPVKSEKKKLHIGLYQYRYGQHVPGKSKTITL
>A0A644THY3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MVETTVRVLLLSDIHGHEEEARRAVMAHQGLDALLIAGDITNFGDANDARAIIETIRSTA
GDMAVLAVSGNCDRLSARHYLAAAGLDLEARPFESKDFAALGAGGGLRRAGITSFERSEG
ELEAALGPGLEAAWKREGPRPRTRPLIAVTHSPPYGTNADLHAGMHVGSKVFSRLMGRYN
PDVWICGHIHESRCVSLEDGTLVINPGPCALGYHALLEIRREGEAPTPTVKASLFSL
>A0A644UXL8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKWLHLSDLHFNPDDDGTDSNYLRDKLKDFLYQNQVVVDYLILSGDFRDASCQDDTDENA
QKVAQFILGITKLVGITNTCNILCVPGNHDLNRDYNNRQELLITEKSKYQTEKGRFVNLP
ELVDAFSFYKKVLNFIYGTDFVNTMFDNCYKISPHKAVVTKDCNILLINTELLAGQSVED
ASGNKCINDAGTLMAGSSYVLNELLTVKPTEKITIAVGHRGLDLLEPTEKRKLVNIFNDY
GVCLYLCGHSHTLWVDDTLGVPQVTVGCIKQENGVRAGFSLGEFCVESNNINISAYSWEN
NSWNKYQHFYKGNSDLHIDLNGVAEAYGGGFDNKIKIVLDGRVREFYCRVPTEGMKFWIE
HSPMISVGSGSLTCVLKNNQYTHLINYNHTFILSNAVWKVIGIDSTISGVTKLTCNRELK
GPSDDFKTGIANKDSISNYRIELLSPIENIGVDQKIELLPLLIKDYKHIKDAKLLLSVSN
QNIIASDKMSIIGKSIGKTDILIWWEDDDEIFLRFSVNVCDEKQENVGYRLYREDLAFNS
KSYFDYSVRIKNKVRIGVEKYINGEQVSVDKPLEFCLISKEDNCSMPIQQLENSVIEVDT
SAMSYGKLYSLTIKGETQMQAEICGKGLF
>A0A7Y7WTZ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas gingeri|TrEMBL
MPSESIQSTPADAVLLVQLSDSHLFAEADGTLLGMNTRDSLQRVIDCVLAEQPAVDLLLA
TGDLSQDGTVASYRQFRELSEAIDAPARWLPGNHDELREMAEAAHHSDLLEPVVDIGNWR
ITLLDSAVPGSVPGYLQDEQLQLLAQALSEAPQRHHLVCFHHHPISIDCAWMEPIGLRNP
EALFAVLDRFPQVRALLWGHIHQELDRERNGVRLLASPSTCVQFAPGSEDFKVDDKSPGY
RWLRLHSDGRLETAISRVRGFDFEVDYGGTGY
>A0A6M4GT13|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Usitatibacter rugosus|TrEMBL
MKLVHITDTHLVTPGQSLYQTDPYQRLAQCIDDVIANHADAAFCVLTGDLAHKGEPAAYQ
GLAKQLARLAMPVYPLLGNHDFRAPFREAFPNALRDEHGFVQGVLKRDEGDFLFLDTLDE
GVNGGKYCEKREAWLRARLDEAGKRPVYLFMHHPPFSIRIPCVDRIALAEPERFAALVKD
RDIRHLFYGHVHRPVCGSWRGIPVSTMRGLNHQVPFDLHTVTPVPKSHEPPAYAVAFIDP
DQVTVHFHDYLDRTTLRRVGEDHYEYVR
>A0A719UA50|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Typhi str. 404ty|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPCVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A2S9ZMU1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio mediterranei|TrEMBL
MKTTPSDESQLSSVRLLQLTDTHLFAPQDGCLLSVNTQESFNAVVAEIVAQGTQFDALLA
TGDISQDHTEASYEKFVAGIEPLALPCYWLPGNHDYKPCMNSVVSSPLIQDVTHVLLGEK
WQVVLLDSQVVGVPHGRLSDSQLEFLDRMLSTHCDRHTLVLLHHHPLLVNSAWLDQHSLK
DADEFWNVVEKHDNVRAVLCGHIHQELDEMRGGVRVLATPSTCVQFKPNSNEFALDVRSP
GWRELELREDGRLHTEVKRLANGSFRPDFNAEGY
>A0A8B3ZLK0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter amalonaticus|TrEMBL
MESLLNLSLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEGQEYDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKCVMVGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLAAAPERHTLLLLHHHPMPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDSIG
PGWRTLELFADGTLKTDVCRLQGTEFRPDTASEGY
>A0A3U5EDQ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella paratyphi A|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPCVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A3V4QJH1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Kottbus|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2T4XY39|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYNALQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLTGAKFRPDTASEGY
>A0A3G9I7T2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas caviae|TrEMBL
METELPQAPDGSVRLLQITDTHLFASAEGRLLAVPTAQSLAAVLERVQANEHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGDHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHHGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRVASQVWRLPLGQFVPDPNATGY
>A0A2A9HXS3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lactococcus lactis|TrEMBL
MIELIIGAVLLSLLIYGIFIEPHLMKVRHVKIAQKQNLKIAHFTDTHFAWHTTSRRFKKF
ARNIANEQPDLIIFSGDLFDKVAWAKNRDWTDLLTILSELKAPLGKFAILGNHDFDDEKS
SRFVEEFLEKAGFVLLKNSSVVKDNLSISGVDDWREGRPDFELEPIDATFSLLALHEPDT
ILDMETIKEFDLILSGHSHGGQIRIGNWRLRNKGSSSADAGLYQLNDRTKLYVNRGIGLT
FLPIRFGVPPEIVYYYI
>A0A6X8KVJ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica I|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLEWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A241Y6D0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter pittii|TrEMBL
MTFQVSTLSQKDHVIIQITDTHLLEYPHLEFVGMNPEESFHAIIQQILNKHPEIDAIIHT
GDLAQAPTPITYNRYIQYMQTLGLPFFQTLGNHDNVDHFPLHKENHQEPVVICLGNWRVI
LLNSAVKGHIDGHLSAEQLENLTALLEEYADNPILLACHHHPFAMKSKWIDHHKLQNSNA
LLTTLAPFKNIKALVCGHVHQDSINTWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLKNDGSFETQVFRLENFQGHINTDISGY
>A0A765T0A9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYLHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCRWLDQHSL
RNAGELDNVLEKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A2A7MB88|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGSLTTEVHRLADARFQPDTASEGY
>A0A2X3KAI2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pneumoniae subsp. pneumoniae|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A6Y6DKQ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar 4,[5],12:b:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A738EBR9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella abortus-equi|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A0T7CV69|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio crassostreae|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHTNVKAVLCGHVHQDMNRDHYGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPHGQFLPDFEAAGY
>A0A3D2B7M7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp|TrEMBL
MESLLNLTVAGGAPVRVLQITDTHLFANKHETLLGVNTWESYQAVLEAIHGQKRECDLIV
ATGDLAQDQTAAAYQHFAEGTASFHAPCVWLPGNHDFQPAMYSGLQDSGISPAKRVYAGD
HWQILLLDSQVFGVPHGELSDFQLEWLEAKLAAEPERNTLLLLHHHPLPAGCSWLDQHSL
RNSAALEQVLEKFPRVKHLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLEGTRFRPDTASEGY
>A0A557PD49|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio algivorus|TrEMBL
MIEPNYIESDRDDITLVQITDTHLFAEDEGELLGVNTLSSFSAVVADIENQALDYDALIM
TGDVSQDHTDASYANFEQCIAPLKKPCYWLPGNHDYQPSMKSVYPSSQIQQDTHLLVGKY
WQVILLDSQAEGSPHGFLTEQQLQYLSDCLSEYPDRFSLVLLHHHPLLVGSQWLDQHCLH
NSDAFWKILEPFNYVKAVLCGHVHQDFHQVHQGVEVLTSPSTCIQFKPQSNDFALDKVAP
GWRSLILKANGQLDTKVYRLEGEEFLPNFEAQGY
>A0A502IJJ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas mandelii|TrEMBL
MPSVSILTTADSALLVQLSDSHLFAETDGTLLGMNTRDSLQKVIELVRLQQPQIDLIIAS
GDLSQDGTLESYQQFRDLTRQLDAPARWIPGNHDEPQIMAEAAVQSALLEPVVDVGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPD
ALFAVLDRFPQVRAVLWGHVHQEIDQDRKGVRLIASPSTCIQFEPGSDDFKVSDQAPGYR
WLRLLPDGQLETGVERVTGFDFQIDYGSNGY
>A0A286X867|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cavia porcellus|TrEMBL
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQ
KDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIF
NVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFITYMMTLEDHYHSDVAYHNSLHAAD
VAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDES
VLENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMV
ETKKVASSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKE
RERGMEISPMCDKHTASVEKSQVLLSTPDCGTG
>A0A671QXB7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sinocyclocheilus anshuiensis|TrEMBL
MLNRELSHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTLREQEKPMSHISGVKKLTHS
SSLTSAALPRFGVKTEQEDALARELNDLNKWGLNIFHVAEYSNNRPLSCMMFAIFQERDL
LKTFRIPVDTFITYVMTLEDHYHANVAYHNSLHAADVTQSTHVLLSTPALDAVFTDLEIL
AALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLHEENCDIFQN
LTKRQRQSLRKLVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLMLDHYNDRIQVLR
NMVHCADLSNPTKPLAVYRQWTERIMEEFFRQGDKERERGMEISPMCDKHTASVEKSQCS
TLEFLHIRIHSQTYMNFNLK
>A0A7J8J0Y4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Molossus molossus|TrEMBL
MAQQATSPDTLTVPEVDNPHCPNPWLNEDLVRSLRENLLQHEKSKTARKSASPKLSPVIS
PRNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFV
HSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAAL
TNLPDRAPSKRSPMCNQPSINKATITESRMERNPYTLLDM
>A0A7T4B5W7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter deleyi|TrEMBL
MARVHTLARRTDAPAMLVQLTDCHLFGEPDTVMLGVNTDASLRAVLRQIEADGKHPDLLL
ATGDLSQDGEPAAYQRLAAILGAAPALEGARIRCLPGNHDLPVAMRHELPEWSVPVTDVG
AWRVVSLDTTVPGSNAGHLPDSQLDLLEAALAEAPGRHTLLAMHHNPMQIDSHWHDSMMI
DNPQALFKLLARWPQVRVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNLA
PGYRWIKLYQDGSMATGVRRVQDALWHAAQPGPASAQAA
>A0A6S6ZLK7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter deleyi|TrEMBL
MTRILQFSDTHFGTERKPVVEAALDLARSLAPDLVVISGDITQRARRGQFAAARKFIERL
SLPVLAVPGNHDIPLYNVFARALNPYGNYKRALGAVLEPVFENAGLLAIGVNTTRPRRHK
DGEISDAQIARVAQRLRQARPGQLRVVVAHHPVRAKVESDRHNLLFGRERALAAWAQAGI
DLILGGHIHLPYVLPASADPALAAGWVVQAGTTCSRRVRGSIPNSVNLITREPSGEGQVC
HVERWDYAAATHAFAPVDKTLVSG
>A0A6S7BA34|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pararobbsia alpina|TrEMBL
MIAKDASDPNVSPTPPPETLDGHRARRRTALSCMAWAGAGMLWTLNGGVPGSRLIGASAQ
AAELDRQAFSFVQISDSHIGFSKDPNLDPASTLREAVDKIHSMPVHPAFIIHTGDISHLS
KPGEFDTATQIINSTRLDVHYVPGEHDVLIDNGDSYFERFAKQGDPKWYSFDQRGVHFIG
LTNVLDLRGGGLGFLGDAQLAWLEKDLSARTSSTPLIVFAHIPLWSLYPAWGWGTDDSAR
ALALMKRFGSVTVLNGHVHQIAQKVEGEISFYTAMSTAFPQPAPGTAPGPGPMKVPADTL
RTLLGVRAVNYVPGRAELAIVDTRLSAREPSLTSGAKA
>A0A3G2SYI8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter wuhouensis|TrEMBL
MNAEKLQLTEFHKDRVIIQITDTHLMDRPEAEFVGINPEENFHAVMDDIKQQYPHIDAIV
HTGDLAQAAFPETYDRYINYMKGFGVDFYHIPGNHDNLRFFPFHTPEPRPAVVSIGQWRI
ILLNSAVSGQTDGRIQNEQLLELKKILAQLQDCFVIIACHHNPFEMRSKWLDQHKLKNAD
ELKAVLEPFQNIKALIHGHVHQESFNEWNGIPFISTPATCVQFKPLSQEFAFDQIAPGYR
CLHLKASGEFETVVHRLKNFKVTINEEISGY
>A0A411H1V5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Edwardsiella piscicida|TrEMBL
MESLFHLAVASGAPVRILQITDTHLFAGQQETLLGVNTYRSYQAVLAAIRAEAHPFDLIV
ATGDLAQDHSAAAYQHFAAGVAALHRPCLWLPGNHDFQPAMVDALAQAGVHANKRALLGD
RWQIVLLDSQVVGVPHGELSDYQLEWLEQTLASEPQRHTMLLLHHHPLPSGCTWLDQHSL
RNAHALDEILRRYPQVNTLVCGHIHQELDLDWNGCRLLATPSTCVQFKPLCTNFTIDTIS
PGWRYLTLYPDGRVTTAVHRLASSEFRPDLDADGY
>A0A4Q7AK16|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter wuhouensis|TrEMBL
MNAEKLQLTEFHKDRVIIQITDTHLMDRPEAEFVGINPEENFHAVMDDIKQQYPHVDAIV
HTGDLAQAAFPETYDRYINYMKEFGVDFYHIPGNHDNLRFFPFHTPEPRPAVISIGQWRI
ILLNSAVSGQTDGRIQNEQLLELKKILAQLQDCFVIIACHHNPFEMRSKWLDQHKLKNAD
ELKAVLEPFQNIKALIHGHVHQESFNEWNGIPFISTPATCVQFKPLSQEFAFDQIAPGYR
CLHLKASGEFETVVHRLKNFKVTINEEISGY
>A0A5C7DBY5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia nevei|TrEMBL
MESLFKLPVASGAAVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAIQAQRRDVDLIV
ATGDLAQDHSQEAYRHFAAGIAQLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLLGD
NWQVLMLDSQVFGVPHGELSEYQLEWMERCLQAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAILLRYPKVNTVVCGHIHQDLDLEWQGRRLLATPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A494U4N1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas veronii|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQANEHPYEVILAT
GDLSQDHSPESYQRFASMMAPLGRPIYWLPGNHDDSPLMTEYLHAAGISESKQLVGDYWQ
VILLDTQVRGKPHGMIGDHQLAALDRALRQYPDRHALITLHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRVASEVWRLPVGQFVPDPNATGY
>A0A834MR71|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vespula germanica|TrEMBL
MDAPLDSFYFSDEDDNLDDKLLTDDDEHADMYDIAGEKEMLEEIRRSLEEDADYPAIKGP
QDIDSHLLTSSAPELIKILLVFSKDDQQMEILANISRRLGWSVSVAKDAEKAVEIFQTRG
HELVIIDHRGQRAVEGDAICRAIKSSPVYHSSVIIALVKKSYFINSEKDEIVTLDLLEKG
FSRALLECSNEGILINELVGIYTSSVLPKTQLAAAHALYLALDRCHDMVHITNERNILQF
LNKVTEKLLGYKTEELVGRNLGEIVHYENFALIEQQLSKGREFEGNMNCKRKNNQMITIN
CRIIPFCITPKKATHYIYVYDTLYLLENSGPLSPINSPLQSTQRASILSNRKSSDVKSAI
SEGHRRYSLQKLHSLQLEAPITKVITLLSNAITETTNPETAGQIDKAIEILKTTELYVPH
LRDDKIYTDPVATDLVGALLSASRNPWDSRRSSADSARLSHLRGISITSTRGPAKPFRGP
QEIMELLDNSLEWSFDIFKLEILTEKRPLVFLGMNIMNMYDVPNKLDCDEKVIHNWLTLI
EANYISTNSYHNSTHAADVMQAIARFMQSDRLKQILDPLDEVAALIAAATHDIDHPGRSS
QFLSNSNNRLAILYNDLSILESHHAALTFKLSLSDDKVNIFKNLDRDTYKILRTNIIDMI
LATEMTKHFEHLARFMNVCSLRIGEDQPMEYNTENVDVTILLQPDNVMMVKRMMIKCADV
SNPTRPLRSCIEWARRIAEEYFNQTDEEKKLNIPVVMPMFDRMTCSIPKSQIGFVDFIIN
DMIEAWDSFIDMPEMLNYMRHNYDKWKEFNDQGITTLQDIEKIQLQPDLKIIKLSEERR
>A0A7U9WX06|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lactobacillus johnsonii|TrEMBL
MLTQDKKTSFWVISDTHLIADSLHDHGQAFSQMQKTSQGKDLYYQETALSAFVRMAQKKK
PAAIVVTGDVTFNGERVSAEKFAEIFKPLEETQLLVLPGNHDIYDGWAREFRGKKQYYAG
QISPRMWRNIFKTSYKNAVSVDDESLAYSVQLNPDYLLILADSNDYGKEEATTAPATAGF
LGREQRRWIKAQLQYASENNLQVIFCMHHNLYAHNPAVNKGYVVDDYRELRKLLAQYNVK
LVFSGHIHAQNIMLPQDPCPATEVVTASFCSNDQCYGVVKVSPKEVSYTCHHFKMKDYLT
DKEKQNWTLTHFHDYLENIQLGTISAELMQKNLYQNHDDLDTVRKMGRLFGEMNYHFFTG
KNHIESEELQKLKKSPIYQRLIADNPHYELYLQTLYDMSNHDNLHVKIKY
>A0A6G6V7C1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas monteilii|TrEMBL
MRPDLMRPVHVVQLTDAHLFADPAGSMLGLKTRDSLRHVVAQVQREQPLVDLLLCTGDLS
QDASVASYEAFRELTTPFAVPTRWLPGNHDEARVMAEVAPELVQAVTDIGAWRVVMLNTA
VRGANHGFLEDDQLAVLKAALEGAGERYCLVCFHHQPVDIGCAWIAPIGLCNAQALFDIV
EAYPQVRALLWGHVHQEWDEVRDGRRLLATPSTCIQFAARSEDFQVSEEHPGYRWLRLHA
DGRLETGVERATDFEVKLDFDSPGY
>A0A1Y1LB55|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photinus pyralis|TrEMBL
MGCSPSVLLDHIHGDSVGSNQEKQLSKKTSIPYLKKESNHSVLHRKSSLPLTPEDEPFDV
YRSPPEIKYGLLIPPNHSPLKLLVVCAHPDPVSEALSKAADKLGYDVTTCHSYEEALEEF
LSKLHDLIVIDARYTSKALDYDTLCRSIRNTRGSQHTAAVALVKRSVFDKDDVTIMSLLD
AGFNRCIAETTNIVHFVNELIQIRHGDIRPLAQTAVNQSLYIALEKCSDIVLITDDSYRL
QYVNRSSERFLGYRYDELLGKSIHEQFIADPLQVTSMTSSLMRAREWQGSLLVRKKSQDT
VSCNCKGIPIICAGRVPTHFVLILDVHGITELTPTSYSLDKPRGSVQSNRRTSMDVRSVS
SDYFRRTSLAKLSALPLEAPITKVISLLSQAQEQTNPNVVSIIDKVIEILNNTELYSPHL
KDDLRLKCDEPVTSDLITALLMQQPQIQLAPSSRRSSNDSTAVRNVSRGISKVRVPAQIK
DLLDTSLTWEFDIFRLEELTNKKPLIHLGMNLFLHFDVPATLNCDEKTLQNWLTVIEMNY
HVDNFYHNSTHAADVMQATAGFLEKDRLKAIMDPLDEASSLIAACSHDVDHPGKSSAFLS
NCDNPLAILYNDVTVLENHHAALTFKLTLGDDRINIFKHLDRETYKVARHNVIDMILATE
MTKHFEHLAKFVNVFCQKTSRVDGESSDYIPITLPDNITLVKRMMIKCADVSNPTRPLRL
CVEWARRIAEEYFAQTDEEKSKGLPVVMPMFDRITCSIPKSQIGFVDYIVHDMFEAWDAF
IDMPELVTYMRQNYIRWKEFDEEGHNTSSDIRKLQNTILMAPAIIPKSSIKRND
>A0A446CI24|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter agilis|TrEMBL
MEDVTEQQKDTVEAVFAILGDPHFTEEHGSHLKIKKNGELASNIPTTNPWAGLTELVASQ
RLEADAILCPGDIAFQSSPTTLSAGWKHLVDLGQLMNCEHVVCATGNHDVTSRSQAETFK
KAVIRNLRAGYGPFEQLKCLHPPYPSVTRDDADHQQGRDHRIRYFGAGLLLVMAAKYQIL
IVNSCGEHGHDEFEHERGTFPQSAVNELKVALTQCDPTRISVAIMHHPPESHTQDGAGAH
DFVDNGQELLKLLADQGDWLVVHGHKHEARLGHASGSGLQPVVFGAASLAIHIEAVKGTV
RNQFYLLKVRLEPRGLTGRFQTWDWSTGRGWEPARPDGDGIYDGATFGARDPGRVITDIA
ALAPLPMDWDEVIRRVPDAGLLPPEARNQVRERLRARHRLHIQVDIKNGQWKKLEKAAP
>A0A862ZLW0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O145|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A328BYW1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Glaesserella australis|TrEMBL
MDDSYTFPLNTPIVRILQITDPHLFASDEMELLGVNTTKSFQAVLDAIKKDPFDYDFILA
TGDLVQDHNREAYHRFAKMVKPLEKPIFWVEGNHDLQPQMGNALALYSQIQPAKHILAGD
FWQIILLDSHIEGLPRGELSSSQLDFLRMKLDAHPERYSLIVLHHNILPTNSAWLDQHSL
SNANQLAEVLKHYPKAKAILHGHIHQEMDKLWQGCRVLATPSTCIQFKPNCHNFTLDILP
QGWRELCLNLDGSIDTRVKRLDCNDFLPDFKSLGY
>I2B576|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shimwellia blattae (strain ATCC 29907 / DSM 4481 / JCM 1650 / NBRC 105725 / CDC 9005-74)|TrEMBL
MESLLNLSVAGGASIRILQITDTHLFAGKNETLLGVKTWDSYQAVLQAIHRQAKEYDLIV
ATGDLAQDHSLQAYYHFAEGVAPFGLPCVWLPGNHDFQPAMYSALQEAGISAAKRVIAGD
HWQIVLLDSQVFGVPHGELSEYQLEWLDRALAQEPDRHTLLLLHHHPLPAGCSWLDQHSL
RNAGALDDVLRRHPQVRTLLCGHIHQELDAQWNNLRVLATPSTSVQFKPHCTNFTLDTIP
PGWRWLQLHPDGTLTTEVCRIDGMQFSPDTESEGY
>B7UIU2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O127:H6 (strain E2348/69 / EPEC)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGSLTTEVHRLADARFQPDTASEGY
>A0A4Y8WGD8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio ouci|TrEMBL
MKVTSISSDQDSIKLLQITDTHLFEPLDGSLLSVKTLDSFHAVVDAIVDSGASFDAMLST
GDISQDHSAISYQHFEQGIEKLELPCFWLPGNHDFKPSMNSVLPSTQIQQVEHVLLGEHW
QMVLLDSQVVGVPHGFLTEQQLTLLDEKLAEYPERNTLVLLHHHPILVGSRWLDQHTLKE
ADSFWRVVEKHNNVKAVVCGHVHQDMNVMHKGVQVMSTPSTCVQFKPNCDDFSLDSLSPG
WRELELHNDGSVSTEVKRLKPGSFQPDFNSAGY
>A0A856Q1M7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Peptacetobacter hiranonis|TrEMBL
MSLYAIGDLHLSSSVDKPMDIFGDKWKNHDEKIKNNWETTVKEDDVVLVLGDVSWGTKMK
DAQSDFDMIHNLPGQKFFIKGNHDYWWTTATKLNKMYDDMKFIQTGFFTYKDYAICGGRG
WICPNEFKFTEEDKKIYDREAIRIEISLKEAKKAGYEKIIVITHYPPTNDSLEDSVFTDL
YEKYGVERVYYGHLHGEESFKTGLKGIRNGIEYNLVSADYIDFMPIKVMD
>A0A5J0JQU4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Vitkin|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>V5Z4H2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia piriflorinigrans CFBP 5888|TrEMBL
MDSLLKLPVASGSRVRILQITDTHLFAGKHETLLGVNTWASFDAVLEAIVAEQAHYDLIV
ATGDLAQDHSMEAYQHFAEGIARLPAPCVWLPGNHDYQPMMFRTLGASSIADQKQVLVGD
RWQAVLLDSQVYGVPHGELSDYQLEWLERAMAAEPQRHTLILLHHHPLPSGCSWLDQHSL
RNPHMLDAVLQRYPLAKTLICGHIHQELDLNWQGRRVLATPSTCVQFKPHCTNFTIDAEA
PGWRYLELHEDGRLETEVRRLNTRMFNPDLDSEGY
>A0A7L6JLL6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. RHBSTW-00524|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRAKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A8J7HK40|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Atlanticothrix silvestris CENA357|TrEMBL
MNQVSPISIAQLTDIHLFASENQRLLGMPTTESFQAVIKRLKKLRSELDLLLLTGDLSGD
GTPESYENLQTLLNPLQIPTYWLPGNHDCATAMDEILNMGMLSRRKSFKRGSWNFILLNS
SIPGCVHGELAPQTLDWLDSELKILGNNPTVVALHHPPLPVNSAWLDTISLRNPQEFFAV
IDRYPQVKLVLFGHIHQEFQRQRHNVEYLGTPSTCIQFQSKSPTFAINQQPPGFRFLKLY
PNGNWETWVERIPYFHPLELAATGY
>A0A844P4A1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aliivibrio fischeri|TrEMBL
MLSETLLNEESDSIRLLQITDTHLFAPEDGALLGVPTRKSFQSVVEQVLQRTPDFDAILA
TGDISQDHTVESYQHFVKGITPLKKPCFWLPGNHDYKPSMGGVLPSPQISACEHLLIGQH
WQVIILDSQVVGVPHGALSDEQLTLLDNALFQHPQRHSLVLLHHHPLPAGSAWLDQHQLK
ESDQFWSVLAKHRNVNGIVCGHIHQELDRIVNGVRLLATPSTCVQFLPDSDDFALDSQAP
GWRTLDLLPNGDIETQVYRLKDCDFSADSEAGGY
>A0A2K8QH28|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dickeya fangzhongdai|TrEMBL
MESLLTLPVARGARIRILQITDTHLFAGERGTLLGVDTYRSYQAVLDAIAAQQCDFDLIT
ATGDLAQDHTQEAYTRFADGIRRFKAPCVWLPGNHDFQPAMVDVLARSGIAPSKHVLLGE
HWQVILLDSQVFGVPHGELSEYQLEWLERSLQSQPERHTLLMLHHHPLPSGCTWLDQHSL
RNAHSLNALLVRFPRVRTVLCGHIHQEMDLDWNGRRLLATPSTCVQFKPHCTSFTIDNVA
PGWRYLELLPDGGVETRVCRLEGNEFLPDMDSDGY
>A0A7Z2PCS5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lactiplantibacillus plantarum|TrEMBL
MMRSQATYLLQNGVQIYLIAGDLFNDFQRSQQFVVDLQALLGAQTRVYWIAGNHDMVHGI
SFDELETGHFDGYLHNRYIDISGTDWRVIGHNGWYDYQYAAQVPDTTAADFLHWKNAFWI
DRAIKQPMSDQERTDLMLNQVKAQLNLAAVDHKQVIFMTHFVPRIDYLRFSDDNRFWNMA
NALMGTPRLGQLLEQFNVAHVLFGHLHVHPQPRVFDQTTYYDQAVGYGLKRINEWQANNF
MAEWYQDTQILDLK
>A0A162G6M5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lactiplantibacillus plantarum|TrEMBL
MKLRKSIFGISCVLFGMMLLSGCQKQTKMTLPPVSHKTLTAMVISDDHVIAPSLHDNGKA
FTQYAANDAGADLKYSATIFRAFIAKALITKPDVVLISGDITNNGEKASHEYVAKQLRRL
TAKHIRVYVVPGNHDLNNPIARRFKGKHQYSTEATSPTQFKKIYHQAGYGQASETDPSSL
GYLVKPSKHTWFLMLNSAIYKSNYQQGNSTVGGGLTDGTLQWLTKVGKQAKQAHATLIPV
LHHNTMDHTVIHQDYTIGYAEDVRKAFTTAGIKLSLSGHIHAQNIKSTKVKNQSLTDIAS
GALILGSHYYGTLKINQSNGTATYHATPLNVSAYIKHHRGNKAMRAYQKYDHDVLYAAGY
NAALSQLYEDRDETQLSSAKVNQLARGMAAANIALFRGTPVKNSAAIQAWQQMPHNTSLR
GFVLATKKLHGNVTWSGSVQ
>A0A1S6INN4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Jeotgalibaca dankookensis|TrEMBL
MKIGVLSDLHIDINDRKLAPGTTYDQLLAELLYNNEVDILLLAGDISSDYRDSLKFLDKM
RNHNVSKLFFVPGNHDYWSVRNNETNTKKIDRIFNERDESLVGRPFILNENQAIVANPGW
YDYGFASKKYSLEEFENKKLNVGGWNDRLYVHWNKPDQVVASEMLQQIERDIQSTNNRDI
ILMTHVATHPQFVVPLPNRMYDYYNAFLGSKSYTALYDKYPINKSIMGHVHFRKTLKEKG
IVYYCSCLGNGRHWWSDDPIVELSYAMETFEIEE
>D1P1I5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia rustigianii DSM 4541|TrEMBL
MDSQLKVTANNPNVVRILQVTDTHLFADTENTLLGINTYRSYHAVLDAIAEQNLPIDLIV
ATGDLVQDQSPKAYQHFATGIEHIPAPCVWLPGNHDYPPAMVGTLKIAGISSAKQVFIGD
EWQILMLDSQLQDVAHGELSEQQLEWMKACLDAEPTRTTLIMLHHHPLPSGCTWLDQHSL
RNSHILADYLKNYPNVKAMLCGHIHQEMDEDWHGIRLLATPSTCVQFKPHCTNFALDCMA
PGWRYLELCIDENGHREITTHVHRLNTREFSPDLESDGY
>A0A4R0EH10|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter terrestris|TrEMBL
MTLSNCHETQQDWTIIQISDTHLMNQEDLEFVNMNPEHSFHAVIKQIQQQYPNVDAIIHT
GDLAQVPVKETYSRYLAFMQRLGIPFYQIPGNHDNIEIFPFYHNQNQAHAIHFGKWSMVL
LNSAVPGKTDGWIEQAQLQQLDQILSKFQQQYVIVACHHHPFDMQSKWIDQHKLKNTENL
TDVLAKHTNVKAVISGHVHQDAWNEWKNIQFFSTPSTCVQFKPLSDDFALDEQAPGFRVL
HLKANGELQTEIYRTEKVQQKINTEISGY
>A0A734HI65|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae serovar 58:l,z13,z28:z6|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGD
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A2S4RTJ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter amalonaticus|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIRAEQHEYDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSDFQLEWLARKLSDAPERNALLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIG
PGWRTLELFADGTLKTQVCRLEGELFRPDTASEGY
>A0A661E0R8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MTTITEHPKSGRVIKVLQITDTHLFADGSGCLLGLNTEQSLDAVTAEVRAHHLPADLILA
TGDLVHDGTPAAYRRIFSHLKNFGLPVYCLPGNHDEARTLQHTLDDELIKYTEDAHLGNW
HFIFLDSTIPDNEGAHLTPETLDMLETQLQSAPDSHTLVCLHHQPVPMGSRWLDTMAVDN
ADAFFRIIDRHPQVRGILWGHVHQTFDGLHKDIKLMSSPSTCIQFLPGSEDFAVDTANPG
YRWLELYPDGRIETGVERIAALPGSVDLASNGY
>A0A837JSJ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella aerogenes|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLHDAGISPAKRVLLGD
HWQILLLDSQVFGVPHGELSDFQLEWLEHQLNAEPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDHILSNYPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTIS
PGWRWLELHPDGALTTEVCRLSGAEFHPDIASEGY
>A0A6J3KG81|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bombus vosnesenskii|TrEMBL
MQELHPFYYHALFKNHENQIHLVHVFHGKTEYDVLRRRSSFEDVAVDDDENADCSALKGP
QNIEAHPLTNSVPSLIKILLVFPKDDQQMDVLATTSRRLGWSVSVAKDAEKAVEFFQNRG
HELVIIDHRGQRAAEADTICRYGELFFKNQPNSSGVRLYILINTIYFRAIRSSPAYHNSI
IIALVKKSFLMHGEKDKIVTLDLLETGFSRALMECSHERLLINELVGIYASALLPRTQLA
AANALYVALDRCRDMVHVTNDKHIVQFVNKISEKLLGYKTSEILGKSIADIVVYDNFVLM
EQHISKGREFEGNMNCKRKNNQMITISCRVIPFSINLKKPTHYIYIYDTTYLSENIGSLS
PTPSQSVYSRGNMIVSQRRTSDMKSSEGRRRSSAHKLHSLQLDAPITKVISLLSNAITES
TTPDTAAQIEKAIDILKTTELYVPSLREDTDPVTTDLVGALLASPRKAWESRRSSVESTR
VSMSKTFSTTTASRMQIKSFRGPQEIAEILERCLEWNFDIFKLEILTEKRPLLFLGTTIM
NMYRVPARLGCEEKVVQNWLTVIEMNYQSRNSYHNSTHAADVLQATARFMQSERLQQILE
PLDEVATLVAAAAHDVDHPGRSSQFLCNSDNKLAILYNDLSVLESHHAALTFKLSLSDDN
VNIFKNLERDTYKQLRQTVIDMILATEMTKHFEHLAKFMNICSARMMDSPQLDDYTDTVD
MSVVLQPENVVLVKRMMIKCADVSNPTRPLKCCVEWARRIAEEYFNQTDEEKRMQLPVLM
PMFDRATCSIPKAQIGFVDFIINDMVEAWDAFIDMPEMVGYMRQNYEKWKEYNDRGISTL
PDIEKIQELPELRIYQLPS
>A0A286BV59|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacteriaceae bacterium JKS000234|TrEMBL
MDSLLTLPAVDGSDIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIEAQQHNYDLII
ATGDLAQDHTVEAYQHFVAGISRLPKPCVWLPGNHDFQPAMVDTLADAGIKSDKHVLLGD
HWQLVLLDSQVFGVPHGMLSEYQLEWLDSALRKYPERHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLQHFPLARNLVCGHIHQELDLDWHGRRVLASPSTCVQFKPHCTNFTIDTLA
PGWRWLTLQPDGTLETEVNRLQSDMFRPDLDSEGY
>A0A506V2G4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mixta tenebrionis|TrEMBL
MDSLLKLPVVSGASIRILQITDTHLFSGRHETLLGVNTWASFNAVLEAIEAEQSPIDLII
ATGDLAQDHSSEAYQHFAEGIARLPAPCVWLPGNHDFQPAMFETLARAGIAEARQVLIGD
RWQLVLLDSQVAGVPHGMLSDYQLDWLENTLAQTADRHTLVLLHHHPLPSGCSWLDQHSL
RNAHALAAVLQRYPLAKTLVCGHIHQEMDEEWHGCRLLATPSTCVQFKPHCTNFTIDAVA
PGWRWLALAEDGAVRTWVNRLGNRAFTPDLDAEGY
>A0A386HID6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia rochesterensis|TrEMBL
MESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAEGISRLPAPCVWLPGNHDFQPAMVDALANADIAPSKQVLVGD
NWQILLLDSQVFGVPYGELSDYQLEWMERCLIAYPERYTLILLHHHPIPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGKLETEVRRLASDEFCPDMDSDGY
>A0A2T3JG86|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium frigidiphilum|TrEMBL
MQTYFLPQTNPNSVVLLQITDTHLFADESGCLLGVATKDSFNAVIDAVDASARPFEAIVA
TGDISQDHTDESYQHFSDGISRWSQPCFWLPGNHDYQPAMQSVLPSPQIKSCEQVLAGDY
WQVILLDSQVQGVPHGELSEAQLLMLDATLKAYPERHALILLHHHPLVAGSAWLDQHQLH
NNEAFWQIIDKYPKVSAVLCGHIHQELDCVYHGVRVLATPSTCIQFLPDSNDFALDKTNP
GWRYLELTQEGQLNTDVCRLQGRRFIPLFNSAGY
>A0A7J0AXT6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alistipes sp|TrEMBL
MKNSILKLCFLSMAAALVFAWSCSKSDPVSTPGDEPVPSRFVSGVVLEKEYNVAKGDVIS
LTGKGFAAGDYLLLRTGSDIRVTPSEVADNKFSFAVPDAVETGTTYRFVLRRANMMQALG
SAKINVISGSGDDFPDKEGATIKGRVVCAGEPVEGVLVSDGVKIEKTDEMGRYWIESKKK
HGSVFVILPSGYNVATKEALPQFWQKLVKAAGELEQHDFELFREDNDRHVMVVATDMHLA
NRSTGDLSQFTAGFVSEMTALCNAESAPVYCLNLGDLSWDLYWYQNRFSLADAKACVKGV
DFQFWSTMGNHDNDAAYQGDWEPEQTYRDEMGPVFYSMNIGKVHYIMLDDTVYKNDGEPG
HSTIAGSRNYDKYFSQDNIAFLKEDLKHVDKSTPIFVGYHCPIRTMAYNAANGWYVNDAI
SLSRQKELLECFEGYSDVTLLSGHSHVNRNIPIEGYAAKMIEQNVAAVCGTWWWTYRYAQ
NNACCDGSPAGYKVFTADGDKVTYKYKGMGVDIDRQFQTYDMNEFMKYWNSDATAKFKEK
MPERAGDYADLSPTSNVVYINVWAWEPAWKIEVTENGRQLEVEQIRKYDPLRMASYDIPR
GATTSLTFPSEYTCHMFAVEAASATSTLEVKVTDTFGVVYAESMTRPKAFTTQYE
>A0A356D6G5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia sp|TrEMBL
MDSQLEVTAKNSKVVRILQVTDTHLFADTENTLLGINTYRSYQAVLDAIIEQNLPIDLIV
ATGDLVQDQSPKAYQHFATGIERISAPCVWLPGNHDYPPAMVESLRVAGISSAKQILIDK
EWQILMLDSQLQDVAHGELSEQQLEWMKCCLDNEPERTTIIMLHHHPLSSGCTWLDQHSL
RNSHTLADYLKKYSNVKAMLCGHIHQEMDEYWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELTVDAQGKRQVNTVVHRLETREFNPDLNSDGY
>A0A701QPX5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae serovar 58:a:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A8E2QS44|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia marcescens|TrEMBL
MESLFKLPVASGAAVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAIQAQRCDVDLIV
ATGDLAQDHSQEAYRHFAAGIAQLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLLGD
NWQVLMLDSQVFGVPHGELSEYQLEWMERCLQAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAILLRYPKVNTVVCGHIHQDLDLEWQGRRLLATPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A4R5LX48|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Seongchinamella unica|TrEMBL
MPDSYHKTCTIDATGDRLRLWQLTDTHLCAETGGTLLEMDTDRSLQLVIAQALDERGTPD
AVLCTGDLSDQGSLTAYQRLEDYLQAIPAPSFWLPGNHDDRNEMLAASRGRHRLPGEIRG
GQWQIIMLDSQIPGEVGGRLGDNELQRLSTALEEGKREGLYALVCLHHQPVSVGSAWIDQ
QMVADAEQFWNLLERYEAVKAVLWGHVHQQIDSRRGAIALMASPSTCVQFAPGSRDFKVD
DKPPGYRWLDLFADGRIETGVSRVTGAEFTVDLESGGYL
>A0A6N2YKV4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Phytobacter massiliensis|TrEMBL
MESLLNLSLAGGARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIKAQQRECDLIV
ATGDLAQDQTAAAYQHFAEGIASFGAPCVWLPGNHDFQPAMFNALQEAGISPAKQVLIGE
QWQILLLDSQVFGVPHGELSEFQLDWLEKKLAASEGRHTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLARFPQVKHLLCGHIHQELDVDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLYPDGRVQTEVCRLQSARFSPDTASEGY
>A0A6I6LJV0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas stutzeri|TrEMBL
MAASTLIAEKDSVLLVQLTDSHLFAEAGGKLLGMDTGESLQRVVDLVIDEQPSVDLILAT
GDLSQDGSLASYQRFRQLSERIDAPVRWCPGNHDELAAMQEATRGSELMQPVLDIGAWRV
ILLDTLVPGSVFGMLRDDQLALLERTLREAPQRHHLVCLHHHPVSIGSRWMDSIGLHNRD
ALFDVLDRFDCVQAVLWGHIHQEFDAVRGGVRLLATPSTGVQFAPGSEDFQVDTRAPGYR
WLRLHADGRLDTGVSRVVGTTFEVDYSIKGY
>A4NVR9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae 22.4-21|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQAVLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTQVKRIQQAEFLPNMQEEGY
>A0A1F0UF16|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus sp. HMSC073C03|TrEMBL
MNNTFECEPASEIVKLLQITDPHLFKDTSKDLLGINTHESFSQVLKEIQTESFDYDVVLA
TGDLVQDSSDEGYLRFVEMVKPLNKSVFWLPGNHDFQPKMVEHLSQSPINASKHLLLGKH
WQVILLDSQVSTAPHGELSAYQLDWLKMKLAENPARHSLVVLHHHLLPTNSAWLDQHNLR
NAHEFSEILSQFNNVKGILYGHIHQEVDGYWQGYQTMATPATCIQFKPDSNHFALDTLQP
GWREIELYPDGRIETRVKRIKHKTFLPNMEEEGY
>A0A7G9YW52|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methanosarcinales archaeon ANME-1 ERB6|TrEMBL
MVKVFAKQKSFKKMKKIFHLADTHIGYSAYRKIDEATGLNQREVDTYEAFKQFVDYALKE
KPDIILHAGDLFDSVRPTNRAICFVLEQLIRLSEAGIPFVVISGNHETPRLKETGSVFGL
FEHIPEVYVVYENKYELVEIDDLKLHAIPHSDDIEGEKNKITLNIDANGSNFNFDVALLH
ASVLGVGLPAFMMGDFNEQVVDIDDLAKLDYLALGHFHGCTRVMENAYYAGSTERFSFNE
VNDKKGFLEVRLSANGEKEVVFHPLKTREMADLEPIVCRSLDAHEIKSAIKGRIQECNPR
DKVARLKVQDIPLHVYHSLDFDELKQLTKSAVHFEIKYEFQKDNELLSAERPTFRSLHSE
FEHFIRTYTIGAHIDKTRLNELGLNYMQAWEEHGEEE
>A0A7U7FCF2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia enterocolitica (type O:9) str. YE56/03|TrEMBL
MESLFKLPMASGARVRVLQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGISRLPAPCVWLPGNHDFQPAMVDALANAGIAPSKHVLMGD
NWQILLLDSQVFGVPYGELSEYQLEWMERCLMAHPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLNWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGRLETEVRRLASDEFCPDMDSDGY
>V0YD54|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli 908573|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A2N7I8K6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio tasmaniensis|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDAIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLDKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGNN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWEVVQQHTNVKAVLCGHVHQDMNRDHHGVQIMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGSVSTQVRRLPHGQFLPDFEAAGY
>A0A855I2X3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIEALEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAILCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTQVRRLPNGQFSPDFDAGGY
>A0A2G4AXH6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQDFDYQAILA
TGDISQDHSAESYQKFESGIKPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAVLCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIGLHQDGTVTTQVRRLPNGQFSPDFDAGGY
>A0A829ZB99|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|[Clostridium] cocleatum|TrEMBL
MRNTGIPWAFIYGNHDTESYATTDKSELNELYKSLSYKTSRTLLYPYIQPNITGRNNQFI
ELRNSDNTLNQALFLIDSNAYTDDGFNKYDYIHDDQVDWYKENIEKLNKEENKTISSLIF
FHMPLQEYETAYNLYEKDSNEVKYYFGSNDEKMIDKICDSEYPSKLFNVAVQLKSTKGMF
CGHDHYNNMSLEYKGIRLTYGMSIDYLAMPGIARDTKQRGATLITVHKDSTIDIEQIPYK
Q
>A0A2G4ASG5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MEIIHLSDLHFGDAQAPFNERELSEALSTYILENTDNPIVVISGDITIKGQACGYEIAST
FVGNLMSLGKVNKENLCVCPGNHDIVDGGFQAFDRFVYGLRRDHSLDFSNDTYKVIAIQD
ILFVVLNSSYHLNHTFGLVDDRCFDVDLSEYSDMKKILVFHHHILNQFDGDTSAIRNGYD
LVQFIEKNRFCLALHGHQHTEQLYHLGKSSTPVISARSGNFEQSGYLNAFNHYKVTNDEV
LIDSFVFEKARRGVKIMRLTR
>A0A2K5C6L3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aotus nancymaae|TrEMBL
FKRILNRELTHLSETSRSGNQVSEYISQTFLDQQTEVELPTVTTEEPPKPVSQISDLHGL
CHSASLSSATVPRFGVQTEQEEQLVKVDQGLVPGSFTHLYTGQWVGLGLIKLHGNRPLTA
IIFSIFQAVFTDLEILAALFASAIHDVDHPGNHHLAVGFKLLQAENCDIFQNLSTKQRLS
LRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYPDRIQVLQSLVHCADL
SNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHP
LWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSGLTNPERGGPDRFQFGLPLEEAEE
EEEEEEEEGEETALDKEALELSDTELPPEASPDPGDLPLDNQRT
>A0A2T3M8X4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium leiognathi|TrEMBL
MQTYLLPQTNPESVVLLQITDTHLFANESGSLLGVATQKSFHAVLDAVDTVAREFDAIVA
TGDISQDHTPESYQEFAGGIARWSQPCFWLPGNHDYQPTMASVLPSEQIKPSEQVLVGEH
WQMILLDSQVAGVPHGQLSQAQLALLDNALSQYPERHALVLLHHHPLPAGSAWLDQHQLH
NNDALWEVVEKHPQVKAILCGHIHQELDRMYRGVRVLATPSTCIQFLPDSDDFALDQENP
GWRYLELMPKGDVITHVHRLEGDQFKPTFDAAGY
>A0A2K5C6C8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aotus nancymaae|TrEMBL
MQGPPAPAPAPGPGSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENGLSSGR
SALDPQSSPGLGRVMQAPVHHSQRRESFLYRSDSDYDLSPKAMSRNSSVASDLHGEDMIV
TPFAQVGFGGGVRWAGQPRLRLLYRRQGPVGNLSSSHQPPPPAEDTGQKLALETLDELDW
CLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQVSEYISQTFLDQQTEVEL
PTVTTEEPPKPVSQISDLHGLCHSASLSSATVPRFGVQTEQEEQLVKELEDTNKWGLDVF
KVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLLLEGHYHADVAYHNSLHAAD
VAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGNHHLAVGFKLLQAENCDIFQN
LSTKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYPDRIQVLQ
SLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVG
FIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSGLTNPERGGPDRFQFG
LPLEEAEEEEEEEEEEGEETALDKEALELSDTELPPEASPDPGDLPLDNQRT
>A0A7Y7N382|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. Scap16|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQDFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLSEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHTNVKAVLCGHVHQDMNREHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTQVRRLPHGQFLPDFAAGGY
>A0A2J7VHT5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Variovorax sp. B4|TrEMBL
MHITPTEQRSFNGILFIGDPHVTSKRPGRRKDDYLASVLAKLEECAEICDDYGLLPVILG
DLLHRSDDNNLRMLNRLMTVLKRFPVPPLTLEGNHDKEETSLTESDALYLLAQAGAVHVL
ETAGLVGTFDVAGQPVRLFAAPYGSAIPRSVPEGEGTAVLITHHDLAFDGAYPGSLPIDP
VDGVMMVVNGHMHDTKPSVIAGATTWHNPGNIEPLSVDLAHHVPKVWLWSPGTGNGAELT
GIELKHGTDLFDLTGLQVAPSDANAAVAALPSTSKFAALITEEAKADVDAERTDDASILH
GDLTQIFGAGAISDATQQLLLGLLGQVRQDAMSL
>L8J940|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium marinum|TrEMBL
MVLLQITDTHLFANEAGSLLGVATKDSFHAVLDAVDDAARPFDAIVATGDISQDHSEDSY
LRFIRGIARWPQPCFWLPGNHDFQPNMASVLPAPTIKPCHQVLAGDHWQVILLDSQVQGV
PHGELREEQLTMLDEALAAHPDRHALVLLHHHPLEAGSTWLDQHKLHNASAFWKVVDQYP
QVKTVLCGHIHQELDRIHNGVRVLATPSTCIQFLPDSSDFALDSQNPGWRYLELTKDGDV
VTSVYRLDGKDFVPEFDSGGY
>W0RD25|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bibersteinia trehalosi USDA-ARS-USMARC-190|TrEMBL
MSDSYQWQTDADTVRLLQITDSHLFSDDHGELLGVNTNDSFQAVLNEINESSFDYDLVLA
TGDLVQDHNREAYHRFGQMVKTLEKPLFWLEGNHDTQPQMGKALSIYQQIQPHKHILAGQ
HWQIILLDSHIENLPRGELNRTQLDFLTQMLARYPERYTLIALHHNILPTHSAWLDQHSL
RNSEELAEVLFPFKQVKALIHGHIHQEVDAIWKGYRVFATPSTCIQFKPNCQHFTLDLLP
QGWRELTLLPNGQIETTIKRLKTNEFLPDFQSNGY
>A6F721|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moritella sp. PE36|TrEMBL
MGADISKLTVKHNVINLLQVTDTHLFATAEKDLLGVKTQLSYRHVIDAILQNQQPFDAVL
ATGDISQDNTPASYQYFAQHIKRLNKPCYWLPGNHDNIPLMADALRAEGVLADKYKVVGD
WQIVLLDSQLTGSPAGYLAPEQLLLLDEQLSAHPDKFALVVLHHNVYPVGCKWLDQHLLR
NADAFLAILAKHPQANHVLFGHVHQQLDKTYAGIHFMASPSTCFQFKPHCDEFTLDARAP
GWRYLQLHSDGSINSQVWRLSNNDFNPDLESKGY
>A0A5V9GE14|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Wandsworth|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A095TDL3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Tatumella morbirosei|TrEMBL
MDNVLVPGIADDLQIKVLQITDTHLFKGKNETLLGVNTWAGYQAVLDEVIASQQHYDLII
ATGDLSQDHSVEAYQHFAEGIQRLPAPCVWLPGNHDFQPAMYDTLAKAGISQSKHVLLGN
RWQMLLLDSQVYGVPHGMLSEFQLEWLETALAAYPNRDTVILLHHHPVASGCSWLDQHSL
RNSHQLDMILQKYPRAATLLCGHIHQEMDEIWQGRRVLATPSTCVQFKPHCSGFTIDSVA
PGWRWLKLGADGQLATQVCRLNTREFLPDMESEGY
>A0A7X6S4S1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio aestuarianus|TrEMBL
MNVSPTLDNTDSIKLLQITDTHLFAPEDGSLLSVNTVDSFNAVVAEICAQNVVYDAVVAT
GDISQDHSAESYLRFADGIAALDKTCFWLPGNHDFKPNMGSVFPCAQIQQPEHVLLGKHW
QMILLDSQVVGVPHGRLSDQQLALLDEQLSAYPQRHTLVLLHHHPLLVGSAWLDQHTLKD
SDAFWNVVTQHHNVKAVVCGHVHQNMDKLHHGVRVMATPSTCIQFKPNSDDFALDRTSPG
WREIELLSDGQIKTQVKRLANGVFQPDFNANGY
>A0A679K550|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium bullatum|TrEMBL
MRLFPISDLHLERRRPETIARPDAPFDVLVCPGDLYEGRPEAGLAALRGIAQGRPIVLVP
GNHEHYAPTGDSRTAPALIAALEAEVTRINDEGEGAPVHLLNHGACVVLDGVRFVGTTLW
SDWALAGRWLDETVPDRPADPVAYAAARMTHPVTGSREFRGSIRKGDGSVWSPADAMAAH
LAQKAELAAALAAPHPGPTVVVTHHPASPLAADAFRAIPGVPWWVPAFYATTALDDLPEA
SRPDLWVSGHFHAGHDLRIGRTRWIANPVEGGTYSAERFVEVG
>A0A679K2F4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium bullatum|TrEMBL
MFRLAHLTDPHVGPIARPRLRQLLSKRATGYVNWRRGRSRHHDMEILAALVADLRTQPHD
HVACTGDLCNIGLPSEWATARDFLQALGTPDTVSFVPGNHDAYVRGSLEGLLKACGAWTS
GDDGTDGVFPYLRRRGPLALIGVSSAIPTKPFVASGRLGPPQIETVEAILTRLGREPEPP
FRVVMIHHPPQPGGASPGRELKDAETFTAMIGRAGADLILHGHNHVGSIGFVRGPDGTGV
PVVGAPSASAVSHGGALHRRASYHVYAVTRADDRYVIEAKERGLTEAGTIADLRVLKLTR
R
>A0A679IM77|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium bullatum|TrEMBL
MFRLAHLTDPHVGPIARPRLRQLLSKRATGYVNWRRGRSRHHDMEILAALVADLRTQPHD
HVACTGDLCNIGLPSEWATARDFLQALGTPDTVSFVPGNHDAYVRGSLEGLLKACGAWTS
GDDGTDGVFPYLRRRGPLALIGVSSAIPTKPFVASGRLGPPQIETVEAILTRLGREPEPP
FRVVMIHHPPQPGGASPGRELKDAETFTAMIGRAGADLILHGHNHVGSISFVRGPDGTSV
PVVGAPSASAVSHGGALHRRASYHVYGVTRADDRYVIEAKERGLTEAGTIADLRVLKLTR
R
>A0A6I9Z125|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Thamnophis sirtalis|TrEMBL
MRRSRTMSFLSMEKSREQLDLATCIGAFPGGGIKRRFSGTPLLPPLACRHATINDLSHGP
EMEHSRVVFTIEESTPAAVKDSDLISFDVENGFSPGRSPLGSQANLGLGLVLQGTTPHSQ
RRESFLYRSDSDYDFSPKAMSRNSSVSSDMHGEDMIVTPFAQVLASLRTVRNNFAVLTHL
REHVCNKRTSGPVNPLSTSKVNLSEDAYQKLAIETLEELDWCLDQLETLQTRHSVSEMAS
>A0A4V2LVI7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter wuhouensis|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMFSALHEAGISPAKCVFAGD
NWQILLLDSQVFGVPHGELSEFQLDWLEAKLAAEPERNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLVNFPRVQNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLHADGTLTTEVCRLSGAKFRPDTASEGY
>A0A7D5DV03|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mannheimia pernigra|TrEMBL
MSEHFRLPINDTVRLLHITDPHLFSHTEETLLNVKTIKSFSAVIEQIKKQIEQTKQGFDL
ILSTGDLIQDQNIAGYHYFAQLTEPLKTPIVWLEGNHDVQPYMSQILGEYSHILPHKQIL
IGERWQLLLLNTQVAGMPYGELSYRQLKWLEEKLNENPKRFTLIALHHNILPTNSAWLDQ
HSLKNSDELAKILQPFNNIKGIVHGHIHQQVDDMWNGIPIYATPSTCIQFKPNCNQFTLD
LLPQGWREILLYENGKIATTIKRLNSNDFLPDLNAIGY
>A0A659KQA1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. E2748|TrEMBL
MESLLTLPLAGESRVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADSRFQPDTASEGY
>A0A1Q3FX90|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Culex tarsalis|TrEMBL
SGTSSSSGRHGPRQTSSLALTPEEEPLDSYPRLISDLKFPNLWPPNPPIKILIAFCKNDP
VFEALVSASHRLNFEPTFVKSHEAAIEAFQNVATGGHHIIVVDARHPRIIEADALGRSIR
NSKGSQHTTMVAVVKKSVFEKDDTAVISLLDVGFNRCIIESPHVSICSSELRQIQHSLVR
PQNVISTQQALYTALHRSREAIIITDDSLRAQYANRASERILNMKLDEIVGRSLSELVTA
DVSNILSQTSRHKDYEGFISTRRKSQETLHIHVRAVPVSCIGRSPTHLVLILESPASGTT
LTALASDALQTLPQGKEVARGSLHSIRRGSFDVRSIASDGLRRTSLAKLSQLPLEAPITK
VLSLLAQVQENCSQDESKLLDRVMEFLKREGLYSPQMKEIRTEDPVATDLIGALLTQGPT
NTISSRRSSNDSIIRGGGRPSTGSIVFTKTRESTQLNELLNNALAWDFEIFRLEELTERH
PLVCLGLELFRRFDVYNTFNCDENTFERWLHKMEEHYCSKNTYHNSTHAADVMQATACYL
QQLSNRELKVMDRMDEATALIAAATHDIEHPGRSSAFLCNSDDRLALLYNDICVLESHHA
ATTFQLTLGDDKINIFKHLDRESYKLARSVIIDMILATEMTRHFEHLAKFVSVFGTDVDA
GKETTHDNEDNQILVRRMLIKCADVSNPTRPLKFCVEWARRIAEEYFTQTDEEKRKNLPI
VMPMFDRTTCSISKSQIGFIEYIIHDMMDAWNSFIEMPEIIRYMEHNYSKWKLFEEQGIN
TLNDIKRKQFTLNTSEAAGTTSSVEEL
>C3LQX6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cholerae serotype O1 (strain M66-2)|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFAAEDGSLLSVNTADSFAAVVAAIGEEQVEFDAILATG
DISQDHTPESYQRFVRGIQPLKKACYWLPGNHDYKPSMHSVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEYPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRIHLGARVMATPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A3Q1BII0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Amphiprion ocellaris|TrEMBL
IFRGSRWRDFTNGLSVGRSPLDSQASPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKG
PSRNSSTASDLHTEDMIVTPFAQVLASLRTVRSNFAVITGQQDRPASKTRSSGSNPPSMC
KTSLAGQYWYY
>A0A1A7QA96|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gallibacterium genomosp. 3|TrEMBL
MSDLFQDESAGVIRLLQVTDPHLFADAESELLGINTFASFQQVLSEIKSSGFESDFILAT
GDFVQDGSEEGYHRFVKEIAQLGKKVFWIPGNHDFQPKMEAVFDVYKAIIQPHKHLLLGE
HWQVLLLDSQLYGVPHGMLNEDELAWLEHHLLMYPERNTLVVLHHHLVPTRSAWLDQHNL
RNPYDFSEVLAKHKKVKGIFYGHIHQEVNAQWQGIPVFATPSTCIQFKPDCAHFTLDSLQ
PGWREITLHPDGRIETKVQRIKEKVFLPKDNMSGY
>A0A0F6B6W2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella typhimurium (strain 14028s / SGSC 2262)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A1C3EQ60|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterovibrio pacificus|TrEMBL
MRTCESLDGQDGVVRLLQITDTHLFSDIHGSLLGVNTLDSFRAVVDKIIAENRYFDAVIA
TGDLSQDHTAESYRLFVEGVAKFDVPCFWLPGNHDHQPEMIDVLNQKPMVRADRVMLGDH
WQMILLDSQVAGVPFGELSESELAKLVSFIDEYPERHTLILLHHHPLLAGSAWLDQHKLR
NHDALWQKLAPKKNVRAVVCGHIHQSLDKMHQDVRVLASPSTCIQFKPNSDDFAIDNLNP
GWQWLELLPDGQLVSKVERLTGIDFKPDMGSSGY
>A0A6J4ZHF0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter insuavis|TrEMBL
MTRILQFSDTHFGTERKPVVEAALDLARALAPDLVVISGDITQRARRGQFAAARKFIERL
SLPVLAVPGNHDIPLFNLFARALNPYGNYKRALGAVLEPIYETPGLLAIGVNTTRPRRRK
DGEISDAQIARVAQRLRQARPGQLRVVVAHHPVRAKVESDRFNLLIGRERALSAWGQAGV
DLILGGHIHLPYVLPASANPAVAAGWVVQAGTTCSRRVRGNIPNSVNVITCEADGDTRVC
HVERWDYAAATHAFAPVDKTLVAG
>A0A2N7N2T1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. 10N.222.52.B12|TrEMBL
MQSSSDSIKLIQITDTHLFAADEGSLLSVRTADSFEAVVKEVLHRQVQFEYILATGDISQ
DHSAESYQRFAEGIAPLEKACFWLPGNHDFKPNMGTVLPSPQIQSVEHLLLGEHWQLILL
DSQVVGVPHGRLSDQQLSLLEEKLSDYPDRHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFENVKGILCGHVHQDMNVLYNGIRVMATPSTCVQFKPNSDDFALDTECPGWRELE
LHPSGDISTEVNRLTDGQFQPDFTSNGY
>A0A4P8DR13|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter cumulans|TrEMBL
MPLINNNDQHKHDPVFDWTIIQISDTHLMDQHELDFVSVNPEQSFHDVMYHIQQQVPHID
AIVHTGDLAQVPVAETYNRYLQFMTGLDIPHYQIPGNHDCTDIFPFHLQQDQAHILHYGA
WSLILLNSAVKDKVDGWISEVQLQQLHQLLSDHPQQHILIACHHHPFAMESAWIDQHKLK
NATHLMDVISQHSNVKIVICGHVHQDSMNTWNNIQFLSTPSTSIQFKPHSQTFALDQVLP
GYRVIRLKNNGEFETEVHRVALSQPQINVEISGY
>Q665W3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia pseudotuberculosis serotype I (strain IP32953)|TrEMBL
MALPADSHNTHNYLVGGRQKQGYHLESLFKLPMASGARVRILQITDTHLFAGEHETLLGV
NTFHSYRAVLDAIIAEQHPFDLVVATGDLAQDHSVAAYQNFAKGISRLPVPCVWLPGNHD
FQPAMVGALAEAGIAPSKQVLAGEHWQILLLDSQVFGVPYGELSDYQLEWMERCLIAYPE
RYTLILLHHHPMPSGCTWLDQHSLRNAHMLAAILTRYPRVTTLLCGHIHQDLDLDWYGKR
LLASPSTCVQFKPHCTNFTLDAVAPGWRYLDLLPDGGLETEVHRLDSDEFCPDMDSDGY
>F4WRM3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acromyrmex echinatior|TrEMBL
MQFFGNIFGITNALVLFSILLSNFFIVQILLVFSKDDQQMDILTNTARRLGWSVSIAKDA
EKALELFQNRAHELVIIDHRAHHADDGDAICRTIRSSPVYHSSVIIALVKKSYFMLDEKD
RIVALDLLKRGFDRALMECSHEGILINELVGIYTSSLLPKTQLAAAHALYLALDRCRDMV
HVTNDKNIVQFLNKVSEKLLGYNVEEMMGRNLSEIVSYENFSLMEQQLNKGREFEGNMNC
KRKNNQMITINCRIIPFCITLKKPSHYIYVYDTTYLSENSAPISPISSPLHPPLKTNTTN
ARKSSDVRSGSINEDKGRRRSSLQKLHTLQLEAPITKVITLLSNAVTDTTNPETAAQIDK
AIDILKTTELYIPHLKEDRAMCSDPVATDLVGALLASPRTTWESRRSSSDSARLSAIKAI
TSPNNSRVQVKNFRGPQEIMEILDKSLDWDFEIFKLEVLTERRPLVFLGLTIMNLYRVPA
TIHCDERTLQNWLAIIEHNYNAENSYHNSTHAADVLQATARFMQSKRLKEILEPLDEVAA
LLAAAAHDIDHPGRSSQFLCNANSRLAILYNDLSVLESHHAALTFKLSLSDDSVNIFKNM
ERDAYKLLRQNVIDMILATEMTKHFEHLAKFMNVCSARIGDGQETYSDSLDMTVILQPDN
VILIKRMMIKCADVSNPTRPLKCCVEWAKRIAEEYFNQTDEEKKLKMPVVMPMFDRLTCS
IPKSQIGFVDYIINDMIEAWDVFIDIPEIVGYMRYNYEKWKEYNEQGISTLQDIEKLQQH
PELQILRLS
>A1SZX9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Psychromonas ingrahamii (strain 37)|TrEMBL
MKVMSTQATKLRSDQQGCLQLLQITDTHLFSDRNKDLLGIKPAESYEAVIKHASRYSSKC
QAVLSTGDLSQDHTQQSYLDFTKQIKTLNLPCYWLPGNHDTQSVMLPSLLQEGLAQSKQI
VSDFWQIILLDSQVEGAPHGFLTEQQLNFLQQALTEYPDKHTLICVHHHVLPVKSAWLDQ
HILKNNQQFLELIKLHKNVRVVLSGHVHQAGDIEFNQVRFLTSPSTCLQFKPNSEDFDVD
DSAPGYRYLALHKNGTITTKVERVAHGEFSPNKNATGY
>A0A735M726|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae serovar 47:b:1,5|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGD
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTQFRPDTASEGY
>A0A6J2DWS7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Zalophus californianus|TrEMBL
MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRNVQLPPLAFRQLEQAD
LKSESENIPRPTSLPLKILPLIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQAN
FVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFA
ALTNLQDRAPSKRSPMCNQPSINKATITETHGYFLPFNSLSIKAYCLFYPP
>Q8ZLZ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A7W3I4A7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter freundii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRARYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTTSEGY
>A0A7Y3Y3P3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio europaeus|TrEMBL
MKVTSSSSNSDSIKLLQITDTHLFEPVDGSLLSVNTLDSFNAVVAAIVEENQSFDAVIST
GDISQDHTAESYQRFEQGIAPLKNTCFWLPGNHDFKPSMNSVLPSTQIKQVEHVLLGEHW
QMVLLDSQVVGVPHGRLSDQQLALLEDKLSQYPERHTLVLLHHHPILVGSRWLDQHTLKD
AHHFWEVVEKHSIVKAVLCGHVHQDMNVLHQGVRVMATPSTCVQFKPNSDDFALDTLSPG
WRELELHSDGQLTTQVKRLPYGFFQPDFNSAGY
>A0A6C6Z703|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2H5XDX9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR17|TrEMBL
MRVLVVGDLHGRWDGLWQALETEKPALVLCVGDWGDPGQVSRDGFERLLDRVPVHTVFGN
HDDLALLQTLQNRDGTPVLLPHGIVLDRDGVRLAGINGIWAKSRRKPHYITAEEVAAIAR
QLAGQEVTVLLTHGCPIGLADETPKGTHGGQRCFLEAFRQVQPRLHLCGHLHRPQARQLK
SGQWVINVGVTALGDYAVVDITPSQVTLLKQVTPSLRAAPSAWEGL
>A0A5A5S1V9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcystis aeruginosa NIES-2521|TrEMBL
MRPFWLESLQVERLTIAIAGLPAALQGIKLVQWSDLHCDEQHLPVAVLQEAIAITNQEKP
DLIFLTGDFITYSPSPIFALVESIKALKSQGGIYACLGNHDSYLPQARETVISALTSVGI
RVLWNEIATPYGENFPIVGLADYWSGEFLPQILEQISPDIPRLVLSHNPDTAMVLRDLRV
DLQLSGHTHGGQVTIPGMGSLPIVLEELRRSLPEPYRPWVPFHRQFSRVVRYWQWSEGFH
RVGENQLYVNRGLGTYFPGRLFCPPEVTVITLVNSSQS
>A0A7M2V508|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. BDA59-3|TrEMBL
MESLLNLPLAGGARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIQAQQRECDLIV
ATGDLAQDQTAAAYQHFAEGIARFGAPCVWLPGNHDFQPAMYTALQEAGISSSKRVITGD
NWQILLLDSQVFGVPHGELSEFQLDWLEKKLSASPERHTLLLLHHHPLPSGCSWLDQHSL
RNAAELDNVLARFPHVRYLLCGHIHQELDLNWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLYPDGSLQTEVCRLQCTRFNPDTASEGY
>A0A379QX82|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSVAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGD
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADVPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A5E4ABQ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marmota monax|TrEMBL
MQGPPAPAPAPGPGSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENGLSRGR
TVLDPQSGAGLGRGAQAPAPHSQRRESFLYRSDSDYELSPKALSRNSSVASDLHGEDMIV
TPFAQVLASLKTVRSNVAALAQGQVHGAVKQASVGNPPPSSQPPPPADSGQKLALETLEE
LDWCLDQLETLQTRHSVGEMASNKFKRMLNRELTHLSESSRSGNQVSEYISRTFLDQQTE
VELPRAAPEESQRPMSEISGLRGLPHSASLSAATVPRFGVQTDEEGQLAKELEDTNRWGL
DVFKVAELSGNRPLTAVIFSIFQALGFPSPDPAPRRRDTHLFQSDPPEWDNPSSGPGPGP
EGTPSGEGIWTQTPAVPWGCDAGDKDREGRDSGEDGGRGCACGPDRPVMDQERDLLKTFQ
IPADTLATYLLTLEGHYHADVAYHNSLHAADVAQSAHVLLATPALEVSAAGTAGQVQGAE
CPPVTSPALGLSGRVHRPGSPGCHLCKCHPRRGPPRGLQPVPHQHQ
>A0A5J6PD86|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cellvibrio sp. KY-GH-1|TrEMBL
MRLIQITDCHLGPQQSETLLGLNTDQSLEDVLQLIQQAEASFDHLLCTGDVASAGHIDCY
TRYERIVRRYFSQPLSWLAGNHDDADIMESSQDALKIQGRLVELGKWLVVLLDSSVPGQV
YGQLAASELDYLEHILTAHPDKNIIVSLHHQPVPVGSVWIDQYVVRNADAFFQLTDAHPN
VKIITWGHVHQEFRALRNGVELLATPSTCVQFKPLCEDFTVDTLMPGYRWFELNDDGSFA
TGVARVTGKNYVIDYKSAGY
>A0A811H0F0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter mucicolens|TrEMBL
MARIHTLTRRHDAPAMLVQLTDSHLFGEPETSMLGVNTDASLRAVLRQIEADGKHPDLLL
ATGDLSQDGEAAGYRRFARILSESAALERATIRCLPGNHDQPSVLRQELSDWSMPVTDVG
AWRIVALDTTVPGSNAGHLCNSELDMLEAALAQAPDRHTLVAMHHNPMQIDSHWHDSMMI
DNPQALFKLLARFAQVRVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHIVDNMA
PGYRWIKLYQDGSMATGVRRVQDALWHTALAAPDSARAA
>A0A8E0FW09|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli 9.0111|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A4U2UEE1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Martelella alba|TrEMBL
MDSLLTLPVANGAIIRILQITDTHLFAGEDEALLGVNTYRSYSAVLDAIEAERHGYDLVV
ATGDLAQDHSPEAYQHFARGIARLPAPCVWLPGNHDFQPAMVKVLDESGISPAKHVLLGD
NWQLILLDSQVFGVPHGELSDYQLEWLEASLRAYPERHTLLLLHHHPSASGCIWLDQHSL
RNAHMLSALLDNFPRVGTLLCGHIHQELDLRWQGRRVLASPSTCVQFKPHCTNFTIDSLA
PGWRYLDLYPDGTLRTEVHRLEGAEYLPDTDSEGY
>D0Z9V0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Edwardsiella tarda (strain EIB202)|TrEMBL
MESLFHLAVASGAPVRILQITDTHLFAGQQETLLGVNTYRSYQAVLAAIRAEAHPFDLIV
ATGDLAQDHSAAAYQHFAAGVAALHRPCLWLPGNHDFQPAMVDALAQAGVHANKRALLGD
RWQIVLLDSQVVGVPHGELSDYQLEWLEQTLASEPQRHTMLLLHHHPLPSGCTWLDQHSL
RNAHALDEILRRYPQVNTLVCGHIHQELDLDWNGCRLLATPSTCVQFKPLCTNFTIDTIS
PGWRYLTLYPDGRVTTAVHRLASSEFRPDLDADGY
>A0A7D4PJZ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia mollaretii (strain ATCC 43969 / DSM 18520 / CIP 103324 / CNY 7263 / WAIP 204)|TrEMBL
MESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTSHSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGIARLPAPCLWLPGNHDFQPAMVDALADADIAPSKQVLVGD
NWQILLLDSQVFGVPYGELSDYQLEWMERCLVAHPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTHYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGRLETEVRRLASDEFCPDMDADGY
>A0A2S2FA59|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter defluvii|TrEMBL
MSAHQVISNPHNPIIIQISDTHLMTDPNDSFIGINPEQNFHAVITQILQEHSHIDAILHT
GDVAQQATVETYQRYQTYMQSLGIPFFQIPGNHDDLAVFPFLNSHPEPTVVDLGDWCLIL
LNSAVKHQVDGWIQSEQLVHLEKILNTIQDKFVILACHHHPFEMKSQWIDQHKLKNTEQL
TLLLSQFTNIKAVLFGHVHQESKVLWENIAFLSVPATCAQFKPRSNEFALDDLAPGYRYL
HLKSDGQIETTIYRLKDYNQSINSEISGY
>A0A1E3UX38|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella xiamenensis|TrEMBL
MLKEAISYSVADENVRIVQVTDPHLFADPEAQLLGVNTSKSLAAVLNTIRAVNYPAHLML
ATGDLSQDYSPESYRQFVSAVAPLNLPCHYLPGNHDDPRIMFLHMQGERIFGQQRILVGK
WQILMLDSTVRGKPGGHMAASQFELIEQAIAAHPDRHTLLVMHHNPILVNCAWLDQHCMD
NGTEFLKCVAQYPQVKALLWGHVHQQLDSLYDGPHGALQLMATPSTCIQFKPQSPYFALD
GLQPGYRLLELKADGSISTNVYRVPGNLFSPDKDSSGY
>A0A6S7CP39|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia ultramafica|TrEMBL
MLLAQISDLHIKRPGALAYRRVDTGAYLERCVAALNALEPRPDAVIITGDLVDQGDPEQY
EHLKTLLAPLAIPYFLMVGNHDERAALRAAFPERAELRSGGEFVQYALDVGPLRVIALDS
MVPGESAGNLCDARFAWLATQLDAAQGKPTVVALHHPPFVCGIAHMDELRLDPAAADKLA
ALIARYPNVERVICGHVHRPMFVRFGGTIASAVSSPAHQVGLDLRDDAPSAFVMEPPAYA
LHRYDPATGIVTHHAYVEAADGPYPFYESEGELID
>A0A2S5F735|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas jandaei|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANNHPYEVILAT
GDLSQDHSPESYQRFASMMAPLGCPIYWLPGNHDDSPLMTEQLHAAGISESKQLVGDHWQ
VILLDTQVRGKPHGMIGDHQLEALDRALRQYPDRHVLIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRIASQVWRLPVGQFVPDPNATGY
>A0A4R2YWZ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rahnella sp. JUb53|TrEMBL
MESLFTLPLVNGAKVRILQITDTHLFAGEDETLLGVNTFNSYRAVLDAIKAQQRDVDIIA
ATGDLAQDQSVEAYHQFARGICELTAPCVWLPGNHDFQPAMVNALQDAGISPSKHVLLGE
HWQIVLLDTQVFGVPHGELSEYQLEWLVRCLDAYPDRFTLLMLHHHPLPSGCTWLDQHSL
RNAHMLANTLVNYPKVNTLLCGHIHQELDLDWYGRRLYATPSTCVQFKPHCTNFTIDTVA
PGWRYLDLYPDGRVETEVFRLETSEFHPDTESDGYE
>Q7N0D8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)|TrEMBL
MESQFELPVVEGTTAKILQITDTHLFASKEDTLLGINTYRSYQAVLDAILKQNADIDLIV
ATGDLVQDQSLEAYRHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGK
HWQLLMLDSQVQGVPHGELSEYQLEWMKNCLDRHPERYAVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQSYSRVKAMLCGHIHQEMDLDWNGIRMMATPSTCLQFKPHCTNFMLDTVA
PGWRYLELSVADNGEFGLTTQVYRLASNEFCPDLDSDGY
>A0A4Z2IUI5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Liparis tanakae|TrEMBL
MALFFLVAEGLLLRINLLSPKSACQHRHKAGCGPSLRPARASAAPWCIVKELSNRPWGAV
AYLLAPFILTDESYQKLAIETMEELDWCLDQLETIQTYRSVSDMASNKVGQRILHVMCVW
KHL
>A0A0S7GTT1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
KVTLQNSPFASFTRLSCPVQRHWDSSEPASSVELLQDPDVRYAVKRVFSGNVQLPRLSCR
PSAQERAQDGAPPEPAAPPTRSIRHSRSLGTLTSCFDVENGLSVPRNPLDAQSSSSSGLV
LQVNYPHSQRRESFLYRSDSDFDLSPKGPSRNLSSTSDLHSEDMIVTPFAQVLASLRTVR
SNFALITGQQDRAASKTRSSGSNPPSMCKTSLAEEPHQQLAIETLDELDWCLDQLDTLKT
RNSVSEMASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKPDDMDIMSPTTKEKDK
KKHPMSQISGVKKATHSLVPSTIPRFGVNVSQEEFLAKELEDIDRWGLDIFKVAEYSGKR
PLTVTMYTIFQERDLLKTFKIPADHFINFTEPYVSVI
>A0A179CX91|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bibersteinia trehalosi Y31|TrEMBL
MSDSYQWQTDADTVRLLQITDSHLFSDDHGELLGVNTNDSFQAVLNEINESSFDYDLVLA
TGDLVQDHNREAYHRFGQMVKTLEKPLFWLEGNHDTQPQMGKALSIYQQIQPHKHILAGQ
HWQIILLDSHIENLPRGELNRTQLDFLTQMLARYPERYTLIALHHNILPTHSAWLDQHSL
RNSEELAEVLFPFKQVKALIHGHIHQEVDAIWKGYRVFATPSTCIQFKPNCQHFTLDLLP
QGWRELTLLPNGQIETTIKRLKTNEFLPDFQSNGY
>A0A379GSL5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia stuartii|TrEMBL
MDSQLEVTARNAKVVRILQVTDTHLFADTANTLLGINTHKSYHAVLDAILEQNLPIDLIV
ATGDLVQDQSPEAYQHFAKGIERLPAPCVWLPGNHDYQPAMVSSLKLAGISSAKEILIGD
EWQILMLDSQLQDVPHGELSEQQLEWMKSCLDKRPQRTTLVMLHHHPLPSGCTWLDQHSL
RNSHILADYLKGYPQVKVMLCGHIHQEMDEYWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELSINEKGERHISTQVCRLNTKEFSPDFDSDGY
>W0LB17|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chania multitudinisentens RB-25|TrEMBL
MESLFKLPMASGAKGRILQITDTHLFAGKNETLLGINTYSSYHAVLDAISAQQSACDLIV
ATGDLAQDHSLAAYRHFAEGVTRLPAPCVWLPGNHDFQPAMVDALAAAGIRPSKHVLLGE
NWQVLLLDSQVFGVPYGELSEYQLEWLERSLNAYPERYTLLLLHHHPLPSGCTWLDQHSL
RNSHMLAAVLLRYPKVNTLLCGHIHQELDLDWYGRRLLASPSTCVQFKPHCTNFTIDDVS
PGWRYLELMPDGQVETQVFRLENDDFRPDMNSDGY
>A0A0S7FEI5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
PFQHEPFKTVAHTCFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSD
YDLSPKSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQQDRASNKRSPM
CNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELT
HLSEMSRSGNQVSESSSMSEE
>A0A0S7FTA1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQNEVEIPSPTS
KTREKKKQQKQQLMTQISGVKKVSHGSSLSNSSISRFGVKTDKEEQLSKELEDLNKWGLN
IFTVSEYSSNRPLTCIMYAIFQERDLLKTFKIPADTFVAYMRL
>A0A8B9XC44|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bos mutus grunniens|TrEMBL
MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQ
KDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIF
NVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHADVAYHNSLHAAD
VAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDES
VLENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMV
ETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQETKS
GRGEWRSAPCVISTQLLWKNPRWASSTTLSIPCGRPGRTWCSLMPRTFWIL
>A0A8C0Q3V2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Canis lupus familiaris|TrEMBL
MEYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSR
NSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATI
TGKEDLVASSSSVWKKNMSSNIRLTNFILQFCSFKEIGPCSLST
>A0A4Y3HTR9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio inusitatus NBRC 102082|TrEMBL
MERQIVEPQIVAAEETVQLVQITDTHLFADDEGCLLSVNTGQSFIAVVNDIVERKVEFDA
IVATGDISQDHSTASYSRFADGVKPLEKQCYWLPGNHDQKSNMISVLPSPQIQEVGHVLA
GEYWQIIMLDSQVEGLPHGYLEANQLELLDNKLTEFPERHTLVLLHHNTLPIGSAWLDQH
KLQRAHQFWEVLGRHQNVRAVLGGHVHQDFEKEHHGVQVLATPSTCIQFKANNDEFALDT
LSPGWRHLQLHKNGQLDSQVYRLEEGCFIPDFEAEGY
>A0A7A2Z6R0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEVRVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A827IPU8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPGRHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNDRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A4E0M864|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWR
TLELHADGTLTTEVHRLADTRFQPDTASEGY
>T1IWR2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Strigamia maritima|TrEMBL
MGCTPSMHTSKTGVIYCQDSEESPSSYTVKDSNHQFAGLAGHYRTDVTSDPAPYAETPMP
MLMPMPPSRSESATGLKLDPKWVPPQRNFISVEKVEVTFLSINLSGLIKTLVLTVRHRSG
LFNVVHNELLVMLRSSGLRLVTFYPFFDVHALENNNVKIGSFAMTYESLKVLFVFPKEDA
QSEAFWWAAKKMQYKTDMVSNHESALACYQERYHDIVIVDGRNSKPIEAEVFCRQDFYSI
FFYFYRCVLSLRAVNGSSNTVSAIIVKRSACLDEDLTVIPFLNAVQVGHLSTGRENGAVL
FDRCRKLGPNFSFQWFVECPSRGVCLSELIQLETNDFRNNLRLQATQTMLAALAHCRDVI
EVTSAKGEMQVDYATTLVHFALFCSISNICYFVAQYINKTGEQLFGYNCSEISGKNIHDI
HKIDNVRTQFNDAIEVQLKNGKEWEGLYMSRRKSGDAISTQAKILPVTTRSNKVTHHVYI
KDCSSRTAFGDLPNGKENINIDVLKGGVKPTRKTSYDIKSLTEGIDYQKPFCFRCIMTTL
MNRRQSMARIAAMSIEAPITKVINFIAAAQENCPVYVAQTLDKALDILRSTELYSPQWLS
QQTKSDDPITIDLLGGLLSQGPKIPLNVRRQSEVSFSKSQSLQPSLSLPSLSIIPSNIKS
LLENESKWSFNVLQLEAITNKRPLVWLGMAIFGRFRVASVLNTDETTLQNWLTLIEANYH
AQNPYHNSTHAADVLQAAACFLDRDHIKQIFDPLDEAACLLAAAIHDTDHPGKNSAFLCN
SNNELAILYNDLSVLESHHSALAFKLTHTDKRVNIFANMDKDDYRTIRHSIIDMVLATEM
TKHFEHLAKFVNSFTKPINEESEFNFEIGQETADNITLVKRVLIKCADVSNPARGLELCI
EWAHRIATEYFQQTEEEKAKGLPIVMPMFDRTTCSIPKSQIGFMDYFVNDMFESWDVFAD
LPELMENLHKNYQYWKEQETRQSLTENEPALEPTSI
>A0A3L1GG86|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKAHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A4D4IWK2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Agarivorans sp. Toyoura001|TrEMBL
MAFTKLDINTAEDGNVRLLQVTDTHLFADDQTGLLGVNTSDSFSAVLDNVKSEQIPFDYI
LATGDLSQDHTKRSYQRFAEKVAELERPSFWLPGNHDLQANMQTLAQYGVLTSKQLISEH
WQVIMLDTQVEGEPHGVMSQQQLDDLAEALAEYPDKHVLIAMHHQAIPVGSNWLDQHNLK
NAEQFFAVIADYPNVRGVIFGHVHQNYEFQFDGVAFIATPSTCIQFLPLSANFALDHQQP
GWRYLQLTPEGRIATRLRRLPERSFLPDPKSKGY
>A0A7Y7J9R9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MSPPDQSRPVHVVQLTDAHLFADPAGSMLGLKTRDSLRHVVAQVRREQPLVDLLLCTGDL
SQDASVASYEAFRELTAPFAVPTRWLPGNHDEAQVMAQVAPELVQAVTDIGAWRVVMLNT
AVQGATHGVLQDDQLAVLESALKEAGERHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDI
VEGYPQVRALLWGHVHQEWDEVRGGRRLLATPSTCIQFAARSEDFQVSEEHPGYRWLRLH
ADGRLETGVERALDFEVQLDFDSPGY
>A0A5E4UFC3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea cepalis|TrEMBL
MSHQGEVKPETGSDARSFDESNPSRRMSRRRAMTCLAWAGAGILWTLDGGVPRGLSLGAP
AAAADKATRQALSFVQISDSHIGFNKAANPDPASTLQLAIDRIRGASQRPAFLLHTGDVS
HLSRAEEFDTAQQIVSSAGLETHYVPGEHDVIADDGRAFFARFAPDSRGVGWYSFDRQGV
HFVALVNVIGLKAGGMGYLGDTQLAWLAADLKGRSRSTPLVVFTHMPLWSVYPAWGWGTD
DGERALALLRPFGSVTVLNGHIHQVLQKVEGNVRLQTAMSTAYPQPAPGDGPGPGPLKVD
ASQLRQALGIRRVDFTALDATPMLSDTSLAS
>A0A6J5CCV5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia sediminicola|TrEMBL
MLLAQISDLHIKRPGALAYRRVDTGAYLARTVAALNALEPRPDAVIMTGDLVDQGDPEQY
EHLKTLLAPLEIPYFLMVGNHDERAALRAAFPDRNELRGGGEFVHYAVDVGPLRVIALDS
MVPGQSAGNLCDARLAWLETQLDAAQGKPTVVALHHPPFVCGIGHMDELRLDPAAADKLA
ALIARYPNVERVICGHVHRPMFVRFGGTIASAVPAPAHQVGLDLREDAPSAFVMEPPAYA
LHRYDAATGIVTHHAYVDKADGPYPFYEPEGDLID
>A0A837DHL0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium carotovorum subsp. carotovorum|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKARQDAFDLIV
ATGDLAQDHTLQAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSAVLDRYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>T1PMT6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Musca domestica|TrEMBL
PHNVISTQQALYTALHRLKEVLIITDDLLRIQYANRSAERLLNMRLDEVISKPLADIFIS
DVSTINSSVQGKGIREFDGILTVKRKNQEGIPMHVRVVPVACIGRTPTHFVFNFDVPGGQ
MDFIATLPQPKEAPRGSLHSIRRGSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLL
SQVQENCSAEEARLIDKVMEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPNVYSSRR
SSNDSIVRTNCSNRQSTIMPAKMKATPLIMEILEESLNWEFNIFKLEEITENHPLLYLGM
EIFRRFDVFATLNVDENVCKNWLAIIERNYHADNSYHNSTHAADVMQATGVFISQLAAKD
LVMDRLEEASALIAAAAHDVDHPGRSSAFLCNSNSPLAILYNDLTVLESHHASTTFRLTL
GDDNANIFKNLDTDTYKVARTTIIDMILATEMTRHFEHLAKFVSVFGTEMEPRDIVQSEE
ESSVLMRRMLIKVADVSNPARPMICCIEWSRRIAEEYFTQTDEEKAKNLPIVMPMFDRGT
CSIPKSQIGFIEYIIQDMMHAWDSFIDMPELITYMQINYSQWKKFEEQGIHTLAEVKAKQ
MSLMNKKSALK
>A0A844I5T4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter adhaerens|TrEMBL
MTTKEEARPLRVLQLTDPHLMARADGDLLGVRTRESLQAVIAEVLKVHGQPDLILATGDL
AQDGSVEAYRVFGESLKVFSCPTAWIAGNHDHTDNLLKVAGEYDASDRQVIRGGWQFVML
DSSVPGKVFGALADSELEFLAEALEQHPDLPAVVALHHHPVDIGSDWMEKIGLTNRDAFW
QVVDRFPQVRIVLWGHIHQEHERERNGVRLMATPSTCIQFTSGSSKFSVEDLPPGYRWFE
FHESGNFSSEVRRAKDFQFQLDQNSTGY
>A0A3Q2YQ61|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hippocampus comes|TrEMBL
LASGHPKFPLKRAITDPLPSCLVPAEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMA
SNKVRITRSRFVYCVSSSRDLRCHPTGSHLGTSLTHRHTNHPLLGLETATEIVSS
>A0A8C0JBC5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chelonoidis abingdonii|TrEMBL
AFQDITDDLINEHFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDY
DLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLPDRAPNKRSPMCN
QPSINKATITGKRD
>A0A7Y3X6B9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Flavobacterium sp. CLA17|TrEMBL
MSAVAVNSPSPLLIAQITDTHLYADAQKELLGLQTSQSFQCVIEQVNALEQRPDLILLTG
DLSQDGTAESYERLHTMVSPLAIPTYWLPGNHDCPKTMAQVLTRSPISPQKSFYADPWHI
VLLDSSVPGCVHGYLSPESLEWLDQELRQSNDAPALIAFHHPPFLSGSDWMNDIGLLNAE
EFFEVCDRHSHVKLVLFGHIHQNFSHQRNQVHYLGTPSTCIQFKPNSVNFALDEEQPGLR
LVTLYPDGKWESEVERVVYSCKLDFAAAGY
>A0A6I4K522|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. PB120|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEADGTLLGMNTRDSLQKVIELVRTQQPQIDLLIAS
GDLSQDGTLESYQLFRDLTRPLDAPARWIPGNHDEPQIMAEAAVQSALLEPVVDVGNWRV
TLLDSAVPGSVPGFLQDEQLQLLARALSEAPERHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDQVRNGVRLIASPSTCIQFEPGSEDFKVGDQAPGYR
WLRLLPDGRIETGVERVTGFDFQVDYGSNGY
>A0A2D0INB2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus ehlersii|TrEMBL
MESLLEVPVAEGATARILQITDTHLFANKGDSLLGVNTYRSYHAVLNMILQQNLDIDLIV
ATGDLVQDQTINAYQHFAEGIARLPVPCVWLPGNHDYQPAMVDTLAAAGISPSKQIVIGQ
HWQLIMLDSQVQGVPHGELTDYQLEWMKKCLDGHSDRHAIIMLHHHPIPSGCTWLDQHSL
RNAPELSECLKGKTQVKAILCGHIHQEVDEMWNGIRVMATPSTCVQFKPHCTNFMLDTVA
PGWRYLELSVAGNNKEAKLQTQVHRLKNNEFCPDLDSDGY
>A0A5C1AHM2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Limnoglobus roseus|TrEMBL
MTPVVVCVPGDLHLTAAGQPNHRAAEWAVDEIERLIKPDLVQFIGDNVQDGTADQYALFR
GLTAKLTRPWHALVGDHDAQRDPTAADFRRHVGDPCGSLRLGGFRFLRLNTQEAHPVGLS
TTQLDWLSRELAAATAAGERVVIFQHNYPFQIWEDFAGPGIDTWRGMVHGHGVHAVLSGH
THYWQLANDGRNVFAATRSIGDPEGGPPGYTVAYFHGDDFAATFRSVNDRGPLVLVTRPR
DALLATRPAHVVRGAADVRARVWSAEPLAQVIVRVESEKPVPLTPVGPLDWSGPLAGDQL
GKGVHRLVVRATDAAGAVGEHVVEVAVDSTGRYTAVPGVRPVVTATDFC
>A0A6N4B431|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio vulnificus|TrEMBL
MQHTSSDTLSENSIKLLQITDTHLFASDEGSLLSVKTLQSFQAVVEQVMARHVEFDYILA
TGDISQDHSAASYQRFADGIAPLEKACFWLPGNHDYKPNMSSVLPSPQITTPEQVVLNPH
WQLILLDSQVVGVPHGRLSDQQLSMLEHYLQASPEKNTLILLHHHPLLVGSAWLDQHTLK
DAEAFWQIVERFPMVKGIVCGHVHQDMNVMHKGIRVMATPSTCVQFKPQSDDFALDTVSP
GWRELTLHANGEITTQVQRLASGSFLPDFTSSGY
>F4T354|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli M605|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>Q31X00|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella boydii serotype 4 (strain Sb227)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A1K2FLU1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces sp. F-1|TrEMBL
MIRVAAVGDIHMGPESQGTLRPSFETLPDCADVLLLAGDLTRHGTPEEAAVVAREIEDLG
VPVVAVLGNHDHHDERPEEVTAILREAGAHVLEGQSAVVTAGEARIGVAGTKGFGGGFVG
RCAGEFGEPLMKEFVRYSRRCADGLHGALKDLDQCGCDVRIALTHFSPVPDTLAGEPPEI
YPFLGSYLLAEAIDTAGADLAVHGHAHAGTEHGMTSGGVRVRNVAQPVIGQAFHVYNLPG
RPG
>A0A6I9NX77|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Notothenia coriiceps|TrEMBL
MYRRSPCARGRIHFDFSEEVVRKLHAANHAHSFDVENGPSTSCSPLDPQASPGSGLVLHT
NFPGHNQRRESFLYRSDSDYDLSPKSMSRNSSIASELHGDDLIVTPFAQVLASLRSVRNN
FTVLTNVQCASSKRSPAATQPPITRVCLPDEA
>A0A7W2TXP9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sediminihaliea albiluteola|TrEMBL
MSYSPSHQYIEVPDTASPLRIVQFTDCHLSKNPGGRLLGMDTDHSVQAVIEQVRQDQFTP
DLVLATGDLADAGALEAYQRLRAYFDKLCPRQFWLPGNHDDCEVMLSLAEADTLMPFELR
VGNWQILLLNSQIPGKVGGHLGAEQLQRIDQALNAAGDLGLHSLLCLHHQPLPIGCEWLD
EQKVRDGEEFLQIVEGHSHAKAVVWGHVHQEVDRQLANCRLLATPSTCVQFAPGSQDFQA
DELPPGYRWLELHSDGRLETGVSRVQGVTFELNLQQRGYL
>A0A1E5D809|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio genomosp. F6 str. FF-238|TrEMBL
MKLSSSSESALGSIKLLQITDTHLFAPADGSLLSVNTFDSFQAVVRDIQAKAFKFDAILA
TGDISQDHSQESYQKFESGIECLQKPCFWLPGNHDYKPNMSSVLPSPQIQCVEHVLLGER
WQMIMLDSQVVGVPHGRLSDQQLALLDEQLTLHSDRHTLVLLHHHPILVGSEWLDQHTLK
DAEQFWNVVDQHQNVRGVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSNDFALDSQSP
GWRELELHLDGSIETQVNRLSDGRFLPDFNSDGY
>A0A5U9GJ12|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella infantis|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A5I8VEI0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Stockholm|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A7W4A3E8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Psychromonas sp. SR45-3|TrEMBL
MNGVHQTVATLNADHKGEVKLLQITDTHLFADSDKDLLGIKTVDSYDAVIEHAQQYTAKC
AAVLCTGDLSQDHSTQSYLDFSERIKTLKMPCYWLPGNHDMQEVMLPALLNEGLAQTKQI
VSEHWQIILLDSQVSGVPYGHLSESQLFFLEDKLKQYPKKHTLIAIHHHVLPVGSAWLDQ
HILKNNAQLIELISQFDNVKAVLSGHVHQAFDVTKNGVRYLTSPSTCVQFKPQSDDFAVD
DKAPGYRYLTLTKSGKINTQVERIDIGDFVTDVNATGY
>A0A399EER5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Calidithermus terrae|TrEMBL
MRFPWLAAHEVNRYARPLAGLERPVRVAHLSDLHIGYYVDAKIIAHWVEATMAQKPDLVV
ISGDLTDTHRAEWIRPAVAELAGLEAPLGAWAVWGNHDYRLRRYKSRDLSDLQGWLEQAG
VRVLNNAGVQLRDDLYLAGVDDLWHGQPDVSQALKDHREGAVLLVCHNPDYFFEVPAKVG
LTLVGHTHGGQVILPILGPVSTSSRYGKRFAEGWFEEPVKGFVSRGLGVSTVPIRFRAKA
EIVIHELHPGKIGKR
>A0A6M1ZVX3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chlamydiae bacterium|TrEMBL
MTIWAIADLHFSFGVPGKKMDVFGDHWHDHDKKIRKSWEAVIQPDDLVLIPGDISWAMKI
KDVIPDLEWIDSLPGTKVMIRGNHDYWWGTQSKVAEVLPPTIHAIHNNVYKWNNFEIGGV
RLWDSDFSFNEFIEFKENPRANKILLEQAENHEENLRIYNRELIRLEMSLKCFKDPDCQR
IVMTHYPPVDDQMNPSPASDLLEKYNVSICVFGHLHNVPHGALPFGEKRGVRYVFASCDY
LDFKPIKIA
>A0A841GGR8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Tolumonas osonensis|TrEMBL
METCTLNNQDDGVVRLLQISDTHLFAGSDRDLLGIATAESFQAVLDAITELPQPYDVVLA
TGDLSQDHSADSYQRFARMASAALPKPIHWLPGNHDHRVLMQNELLAAGIRPEMRLVSEH
WQVILLDSQVYGTPHGWLSHLQLEQLEAALQQHPEKHALICLHHHTFPIGSIWLDQHDLK
NANDFLAILARYPRVKAVLCGHVHQEYDQYHQGIRFLTSPSTCIQFKPLSVDFSLDGMSP
GWRYLQLYPDGRIATQVWRLEPGRFVPDLQSTGY
>A0A5E4LIY7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKILALSDLHTDEMLLDRLRAVSAKGQYDLVILAGDITNRGPVSYAEEVVSLFPKVYAVH
GNMDTPDVVEKLREMGVLIHGKKVRVGEWNIVGLGGSNPTPFSTPSEYSEEQIGQTLAKA
GVDEFSILVSHPPPYGVFDSVGPVHVGCRAVRDIIEKKKPILCICGHIHEYEGKEIIGET
FVVKLGPAEKLRAAEIEIKDSIEVKFISL
>A0A5E4I7Q7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKKIFPILILGMIILCGLVSNFYRLDITETNVHASMVTPTNFTIIALPDTQYYAESYPTI
FINQTQWIVNHKDALNIVYVTGEGDITDIGIQDIQWQHADAAYTLLEDLTTTHLPYGIPY
TIPPGNHDQPTTLFNQYFGVSRFTGRSYYGGHYSTTNNNHYVLFNASGISFIAIALDYNP
STAALNWADGVLQTYNNRKAIVIEHCILNVDASWDGNGQMIYDTLKHNPNLFLMLCGHNH
GENRRTETYNGHTINILLADYQNYRKGGNGYLRIMTFYPATEQIKVKTYSPYLDQYQTDA
NSQFNLNYNTTPSPLTIESITDGLGIKAVIKNTGTVDVKNVSWKIQLDGGIILVGKSKTG
TVDIAAGDTITIEDFVFGFGKTTITVTVGDVEQTAAAIVLLTLVLNVA
>A3V0M6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus (strain 12B01)|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIEPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGGN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAILCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTQVRRLPNGQFSPDFDAGGY
>A0A8C1A3A2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyprinus carpio|TrEMBL
MVYHTCTAMKHVCVHIYYSPNIPDMKRHTQKKKSVFIFIEVKFSLDVENGPSIGCSPLDP
QASPGSGLVLHPNMASHGQRRESFLYRSDSDYDLSPKSTSRNSSLVGEQLHGEDLIVTPF
AQVLASLRTVRNNFSILTNVQCPSSKRSPVSSQPPVTKANLSGKILCIRSQTLN
>A0A8C0YFS9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyprinus carpio|TrEMBL
MPWPLNSPEMNPIEKCVCITSPSTCNSDVEELTGGARNAPQNCPGMFRKLAVNKTVRQRR
RFTVAVSHTCLDVENGPSIGCSPLDPQASPGSGLVLHPNMASHGQRRESFLYRSDSDYDL
SPKSTSRNSSLVGEQLHGEDLIVTPFAQVLASLRTVRNNFSILTNVQCPSSKRSPVSSQP
PVTKANLSGKILCIRSQTLN
>A0A4U1WEL5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. F12|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHTNVKAVLCGHVHQDMNRDHYGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPHGQFLPDFEAAGY
>A0A6N4XTC1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chryseobacterium fistulae|TrEMBL
MQRNFLIITAIFLFLEVYIYQAIRTLTDSLWVKLGYWIITLTIYGVFAYEMTHYQRSDRS
TVRVQIMISLFLIFILPKVFIVLFLLIDDIFRGGSYLIGLTRPTENFFPERRKFLSLVGL
GLGGVLSALFIDGITFGKYRHKVRKVKVKLTHLPKSFKGYKIIQISDVHSGSFSDPSKLK
HAIELINEQKPDLVLFTGDMVNNVADEFKPFIPLFSKIKAKDGKLAVLGNHDYGDYVTWG
SLEEKKKNLETLIDYEKQAGFDMLRNENRIIEKNGEKLYILGVENWGLKPFPQFGKIDEA
LKNVPNSATKILMSHDPTHFDYVVKKHPGNIHLTLSGHTHGMQFGLDLKNIKWSPVQYRY
PKWADLYESEGKLLYVNRGFGVLGYPGRVGVLPEITLFELA
>V3Q1D5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. MGH 24|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMFSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLTKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHSDGTLTTEVCRLTGAKFRPDTASEGY
>A0A5U3E2Y2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. arizonae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLTDAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAAELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELHANGLLETEVHRLQDTRFRPDTASEGY
>A0A7K0DCG4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nocardia macrotermitis|TrEMBL
MTVTTLASAGGTGANGDALMTCCGPNRRRMLAALAAAPIMLATGTARAQPNSMIATDLEV
VTLTPTSAIATWTTLGTDAAGNRIPVDAGTQVRLTPADAVGPARLVHDDADRTPYHYAEV
TGLEPGRSYRFEAWSDGVRAVPAATVVTHLPGSPECTGVFSTLALPPGRLLRTVALCNDV
HFGEEIAGLITNGFPPGVRQEPGLAPYPEVMLTAMLDDLRRPDRGANQLLLAGDLTAEAT
PDQSRAVRAHLDSWGRSGRDWFAVRGNHDRPHVGADYAACRPVSDADHHDCWGESFGARG
QLVDHRVGELRLLGLDTTRLDQAGGTIDPDQFAHLREVLRADPDRPTLVFGHHPVTQNSA
LSNINGPDFILNRADATTLQNLYRTAPGVFLHHAGHTHRNRRTAPDLPLNVEFLEVGAVK
EYPGGYTLVRVYEGGYTVNFYKTRTPAARRWSTRSRAEYLGLIPEYTLGTTADRNHVVLR
DFSGLG
>A0A2L1UVV3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rahnella sp. ERMR1:05|TrEMBL
MESLFKLPLVNGAKVRILQITDTHLFAGEDETLLGVNTFNSYRAVLDAIKAQQRDVDIIA
ATGDLAQDQSVEAYHQFARGVSELSAPCVWLPGNHDFQPAMVNALQDAGISPSKQVLLGD
DWQIILLDTQVFGVPHGELSEYQLEWMERCLNAYPDRFTLLMLHHHPLPSGCTWLDQHSL
RNAHMLANVLVNYPKVNTLLCGHIHQELDLDWYGRRLYATPSTCVQFKPHCTNFTIDTVA
PGWRYLDLYPDGRVETQVFRLETSEFHPDTEADGYE
>A0A7Y3HKW4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonadales bacterium|TrEMBL
MKRPIIVSRFPVFEKDNSKDLLDSQTLELPASDDNATLRVLQITDCHLGEAIGEVLAGMD
TDASLASVLELLVAEQSEHGEINAELLLATGDLSNLGTASAYYRLEKILQPLGLPMAWLP
GNHDVRDLMIDSVGIDRMPRLVRLGRWAICMLDSAVPGQVGGELGATELNELRIELDSLP
ADVHIMICLHHQPVEVGSAWLDQQKVADADRLFALLKNERRVKAILWGHVHQEFYGTHPG
LPGVKLIASPSTCIQFAPGQRDFKLDTAMPGYRWLDLHADGSIQTGVSRVEGADLRIDLA
SSGY
>A0A0H3H1J7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella oxytoca (strain ATCC 8724 / DSM 4798 / JCM 20051 / NBRC 3318 / NRRL B-199 / KCTC 1686 / BUCSAV 143 / CCM 1901)|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFTAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGE
HWQVLLMDSQVFGVPHGELSDFQLEWLEQKLTEVPQRYTLLLLHHHPLPSGCSWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A2S9XUD4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enhygromyxa salina|TrEMBL
MPDYYRDTPFSSAWMRLTSIEAEPIRTTKFFGCYAFERAPALAGITHEDGQRFVNKLVLD
ADELRAMDTTIWRVRPARSDDRHDRILVARQQTTQALSERPIPLRSSRILHLSDLHFATE
RTNRNEHIWELTGEGGSTLQQRIVQALGGDRTVGLVVISGDLTFRAADDEFYEAFRFVHG
LMGALGLGPGHLVVVPGNHDLAWTRQRDQQWNRDETVTEAPASAQRAYRESFYDRVFRHA
AAEHLGMARRFICPNGLVLEVGGLNSSSLEQGSNWLAGMGRVNDAALTDIAETLEWKADR
ASMALRLLVHHHHLTPIEDVVPTSEFYRGFGMAADAKRTLRQAARHNVQLVLHGHRHQPF
IETTNVYAELEHAETKWQLGRVGIIGAGSAGSTSVNNNDNYFNILEIQGGQLDLQVFRAR
SPHGSRGDFRMIQEWSAPMLLEAGQLRLGDWALRRRSAG
>A0A5Q2VEA3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia proteamaculans|TrEMBL
MESLFKPTVASGARVRILQITDTHLFAGENETLLGINTYRSYHAVLDAILAQQRGFDLVV
ATGDLAQDHSLAAYRHFAEGIARLPAPCVWLPGNHDFQPAMVDALADAGIAPSKQVLVGD
HWQVLLLDSQVFGVPYGELSDYQLEWMERCLQAYPERYTLMLLHHHPLPSGCTWLDQHSL
RNPHMLGAVLLRYPKVNTLLCGHIHQELDLEWQGRRLLASPSTCVQFKPHCTNFTIDEVS
PGWRYIDLLPDGRVETQVFRLENDDFRPDMDSEGY
>M3XNV5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mustela putorius furo|TrEMBL
MYHRHPRTPILDRDPEVLGSRNSQDAVARNCREVGKNEGRGSYHLHRGTSQKPSPARGLN
LNRRSFLPDEKCKLFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDS
DYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTVLTNLHGTSSKRSPAA
ASQPPVSRVNPQGSNAIPTRLTRGSKCSFSTFLEGRTHRRLVFLVPLEICDK
>A0A8H2NVX6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEADGALLGMNTRDSLQKVIELVRAQQPRIDLILAT
GDLSQDGTLESYQQFRDMTRQLDAPARWIPGNHDEPRIMAEAAVQSALLEPVVDIGNWRV
TLLDSAVPGSVPGYLEDEQLQLLARALSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQVRAVLWGHVHQEIDQLRNGVRLIASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGRLETGVERVTGFDFTVDYGSNGY
>A0A5E6N0K3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MSSVSTVSPDAPALLVQLSDSHLFAEAEGALLGMNTRESLQGVIELVRTQQPRIDLVLAT
GDLSQDGTLASYQQFRDMTAPIGAPTRWIPGNHDEPQIMAHAAVHSDLLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDSQLQLLAQALSEAPGRHHLVCFHHHPVSIGCAWMEPIGLCNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEAFKVSDQAPGYR
WLRLHADGRLETGVERLQGFTFTVDYGSNGY
>A0A5E7WJE4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MKLQIYSDLHNEFAVFEAPAVAADLVILAGDIHTKARGVIWAGEAFSCPVIYVCGNHEFY
GRHIDHTLRKMKDAALPHVHVLENETFIWNQTRFLCATAWTDFSATGNVVAATQTAWEWM
NDFRVIRIDDNFRRLRPTDLISRNHATHDWLARELDKPFDGKTVVVTHHAPVPEVAGGKH
DGHLSAAYTNRWHALVEKADLWIFGHTHRAVDITLGRCRVVSNPRGYPREQTGFLPDLVV
SLS
>A0A737M0G2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. houtenae serovar 44:z36[z38]:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>D8MX30|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia billingiae (strain Eb661)|TrEMBL
MDSRLLLPAAGGSTVRILQITDTHLFAGKDETLLGVNTWASYDAVLQAISASPRHYDLIV
ATGDLAQDHTVEAYQHFAEGIARLPAPCVWLPGNHDFQPAMFSTLAESQIADEKHVLIGD
SWQIVLLDSQVFGVPHGMLSDYQLEWLENTLAKEPHRHTLVLLHHHPLPSGCTWLDQHSL
RNPHSLDAVLQKYPLATTLLCGHIHQDLDLNWNGRRLLATPSTCVQFKPHCTNFTIDSEA
PGWRWLDLLPDGRVETQVERLATRAFSPDPDSEGY
>A0A231H3L4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nocardia cerradoensis|TrEMBL
MTGPERTDGVVRIAAVADIHLGADSRGTLRPAWERLPAEADVLLVGGDLTRHGTLDEARV
VATELADPGVPVIAVLGNHDYHSDLQDDITALLCDHGIRVLEGTSTTVTVGPYSLGVAGT
KGFGGGFAGKCASVFGERIMRDFASYTVDLADALHVALCGLDTDVKVALTHYSPCGDTLH
GEPPEIYPFLGSYLLGEAIDTCGGADLAIHGHAHAGYERGTTPGGVRVRNVAQPVIRAAY
TVYDLSVPERADGSGAPSESHEAARTPA
>A0A5M8P2S0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Ordinivivax streblomastigis|TrEMBL
MNAAGLAVLFSLSPLLGKGQGVVETPRFVVMSDVHFGNTKGVGPMIKVPKALKNLLGKTP
AADAIFIVGDLTDSGTAAQYTQLKTVFNDKANIPDGVEAYYLMGNHDFYPSDKELAKNNY
LTLGQPLHQYIKIKGYPFITISMNSSGNSGSNLYDATAKQFLTDSLARAAQDYPGKPIFV
FIHVAPKNTVYGSYANDGNWATDDFSDILKKYPQVIVFSGHSHYSLRDPRSIHQGDYTAI
NDGSSTYSEIEPNSVNVGIHPEKYDNITEGLIVNVRANGDVNMERWDTYRNEEMLPQWNI
KAPHDGTQFSYKGRNGMPPPAFAVGAVPVVTKTAATTCNVTFPQANDNELVHHYLITIKE
GTQTVASFSKFSQFYLNSQMPQTLTVTFSELPGGASLVAEVTAIDSYGNASAPMVSAPFT
TEVVQVVRPVADILDVVFGENGEAQDISPLRNTIISGSTKPTTASNATYNRQSALFSGIN
TCYYRVDYAGNQVIKDAFTNGFTFEILYKTNSTGSTFSPMSAQESGGAGFEHPSGGQAQF
WAHIGGGYKTIKSARSVATNQYYHEVGVYDKVAGKLRLYLDGQDAGSMDVSGAFGFPNNS
AAHWIAIGGDANTGSTAQSPLNGEVVIARMYGKALSYDEVRLLYSSLTEPQGNSLPAIQG
IQGKSLLRNLWGVPVDTTSNLPAGVYLLTSGGQTKKVIVNK
>A0A1W1URA3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurella testudinis DSM 23072|TrEMBL
MRFIQVTDPHLFADKKSELLGINTFDSFAAVLSEIKQTPFNFEFVLATGDLVQDSSLEGY
RYFSEEITRLQKPVFWIPGNHDYQPHMVDVLNQQSDYISPLKHIIINEHWQILMLDSQVL
NVPHGYLNQYQLDWLLAKLEQYPELHTLVVLHHHIAPTRSAWLDQHNLRNTSEFLSCLSQ
HRHIKAIISGHIHQAMDIQWNNYRILTTPSTCIQFKSDSYHFSLGVMPPGWREFELYPDG
TLKTQVKRIKENLFTPDFNISGY
>A0A182PDQ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles epiroticus|TrEMBL
MEERDEATSGCFKMKSFFRKYQSKSMESLCKPTSTVLTVKQLESMPQAERTRPARRYSLL
GTPSPMETGDERKATRRVSSSIGHCVTLPEEQQNGVLPTGEKPLLMMEEPMKKLDNGDSL
ITGPKLTTELINSPEPRRSLPLEHNQSEQNQSDNGSEQKVYFRTNSAPIFRPRSYGRRSN
GFKVFRFPDIIEESTFAEPTILSAREWRRFVAFRSLPADSIDPAVRQQILADFDVHFYEY
DERAQPPSALEAITLETVTFAVGEPEPGSSHHRPHQQRWPEESDVQDIILPTLSEEEALF
IERLVSDLKFPNLLPPNPVIKILIAFCKNDPVFEALVNASHRLSLEPTFVKSAEGAIDAF
QNPSSGGHHIIIVDARYPRTIEAEALGRSIRNSKGSQHTTMVAVVKKSVFEKDDTAVISL
LDVGYNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQALYTALHRSREAVIITDDTL
RAQYANRASERVLNMKLDEIVGRSLNDLVTADISNILSHTSRYKDYDGYLTTRRKSQESS
QIHVRAVPVSCIGRNPTHLVLILESSSSALVSSNAIGEALQTLPQGKEVPRGSLHSIRRG
SFDVRSIASDGLRRTSLAKLSSLPLEAPITKVLSLLAQVQENCSLEEAKLLDRVMEFLKR
EGLYSPQMKEIRTEDPVATDLIGALLTQGPTNILSSRRSSNDSIIRGGGRPSTGSIVFNK
TKESSQLSDLLQTALDWDFEIFKLEDLTEKRPLVCLGLELFRRFDVYNTFNCDEMTFKLW
LIEMEKHYHSENTYHNSTHAADVMQATAVYLQQLSNRELKIMDRMDEATALIAAATHDID
HPGRSSAFLCNSDDTLALLYNDICVLESHHAATTFRLTLGDDKINIFKHLDRDMYKLARS
IIVDMILATEMTRHFEHLAKFVSVFGTDVESKEPLPPDNDDNQILVRRMLIKCADVSNPT
RPLKFCVEWARRIAEEYFMQTDEEKRKNLPIVMPMFDRTTCSISKSQIGFIEYIIHDMMD
AWNSFIEMPEIIRYMEFNYSQWKLFEEQGINTLSDIKRKQMSLTEDTASSISLEEKF
>A0A6S5VRG7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas caviae|TrEMBL
MRLLQITDTHLFASAEGRLLAVPTAQSLAAVLERVQANEHPFDLILATGDLSQDHSPESY
QRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQVILLDTQVRGKP
HGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNADDLFAVLARHPQ
QKTILFGHVHQEFDEVHHGVRLIASPSTCIQFKPLSDGFALDESGPGWRYLTLHPDGRVA
SQVWRLPLGQFVPDPNATGY
>A0A8B2XQH6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. AM17-18|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAEHRDCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
KWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLTKFPRVKHLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLAGAQFRPDTASEGY
>A0A419ATJ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium carotovorum|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKARQDAFDLIV
ATGDLAQDHTLQAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSAVLDRYPQVNAVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A846KX07|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Anoxychlamydiales bacterium|TrEMBL
MQIFAISDPHLSLSTPDKNMQDFGDTWKDYQEKIKNNWEKNITDNDLVLIPGDISWAIKF
KDALIDLEWIHDLPGKKVIIRGNHDYWWPSATKLKEALPPSISFIQNNSLNFGEISIAGS
RLWDSTEYNFKDYINFVFNPKERKDLQGNIHKDLSERIFIREIERLKLSLEGIDKNAKTK
IVMTHYPPISADLKDSK
>A0A7Y4FH67|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. 99-8-1|TrEMBL
MKLSASKNNHKVQLLQITDTHLFSDKNGCLLSVNTFDSFRAVVDEIVLNKQSFDAILATG
DISQDHSVESYQRFEQGIEPLEKPCFWLPGNHDFKPSMHSVIPSEQIRSENHFFAGEHWQ
VILLDSQVVGVPHGRLSETQLEFLDNKLSENPSLHSLVLLHHHPIPVGSAWLDQHTLTEA
QDLWAILAKHSNVKALLSGHVHQDYDERHNGVRVITTPSTCVQFKPDSDDFALDALSPGW
RMLNLFDDGRLETEVFRLQNGRFSPDFTSGGY
>A0A0B9GKW2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium gaetbulicola|TrEMBL
MQNFTLPQTNRDSVVLLQITDTHLFADDGGSLLGVTTKDSFHAVLDAVDAAARPFDAIVA
TGDISQDHTEYSYQRFCEGIARWSQPCFWLPGNHDYQPSMQAVLPSPQIKPCHQVLAGEH
WQVILLDSQVKGVPHGELSGEQIDMLDQALSAHPNRHALVLLHHHPLPAGSAWLDQHQLH
NSEPFWQVVGSYPQVKAILCGHIHQELDRIHRGVRVLATPSTCIQFQPDSQDFALDQKSP
GWRYLALHRDGQLETQVHRLEGHDFTPNFDSAGY
>A0A8C9L9A9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pavo cristatus|TrEMBL
MTAKDSSRELATPESEIYIRTFKEQMHLELELPKLPGNRPTSPKISPRSSPRNSPCFFRK
LLVNKSIRQRRRFTVAHTCFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFL
YRSDSDYDLSPKTMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTANK
GISQCPPENIPRSAGGTKPFAQPESKSSNVETITHPASQSVAECASRRCGASHVVSKQPC
RVTPCCQLMI
>A0A2P2ED13|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Phycosocius bacilliformis|TrEMBL
MTTIIHLSDVHFGDADATRLVAALEAIKALEPDCLVLTGDLTQQGKAQEFADAVRWLAQL
DLPIVGCPGNHDTPMFNLPARLFRPFGRFEALGMRSAWQSSDGWVEVIAATTALGTQWTF
DWSQGDYGQASVRQALDNLAQSTAKIRLLAVHHPPETPPGAYVKSNPRGLLQFNQWLAQT
CRPDLLLCGHVHGYFDFSAAATQGLRVLTVPSLASRRERGAGSGFAVIRLKHGDHAIRPE
MHRFSEGHYRPS
>A0A2P2E6W2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Phycosocius bacilliformis|TrEMBL
MVIQARKSPLRHCFLTVIRAGLFALALTSSCLTPSYAHPGHDRNTPTLAPWQQASAWPDR
VITTFETDPTTSFAVTWRTDASVTRAVAEIVRATPDAQFDIGAVRKAADSEPLDLETIRT
ATQELKMPWNAGLSPVTYHSINFDGLEPDTLYAYRVGGGEGKWSEWFQLRTAPAQGPIKF
IYVGDAQNGLMSHWSRVIRAGFQKMPDARFIIHAGDLVNRGSRDLEWAEWFKAVGFIHGM
IPAIPVAGNHEYDSFGLIPTTNRLLSALWRPQFRLPSVDSLPATVRETAYQIHYGPNLDI
FVLDTTSDTLKVQAAWLDEALSKSTARWRIVTMHHPVFSSTQGRDGDARREIILPVLSKH
KVDLVLQGHDHTYARGPILETQRPEREVVGDGEDVAMMFVNSVSGPKQYRFKNSRWDDYA
PSGVRLDRFAEGTPFFQTIEIVDGKLSYRAYAATGDLYDSFDMTKDEQGRKRVTKGPPAT
LTQRAYGPLNPYRDFKDPD
>A0A644T8G9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MPFKLQYASDLHLEFPANKEFLKQHPLQPVGDVLVLAGDIVPFAVMDKHQDFFSFLADNF
KTTYWLPGNHEYYHVDIAEKSGVLNEAIRSNVFWVNNTSVLHEHVKLVFSTLWSRISPGY
QWQIERSLSDFHVIKHKGYRFSAEQYNQLHAESLAFIQNELINNQNGQTAVFTHHCPTFL
NYPEQYKGDILNEAFAVELHDLIEASEIASWVYGHHHTNTPEFTIGNTKLITNQLGYVQR
NEHRLFELNKVI
>A0A7G2D053|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microbacterium sp. Nx66|TrEMBL
MSAAKGTPPVFGRYAPASHVLIHVSDPHFLAGGAALGGRYDVERTFARTLEAIRAVHPAP
AAIVITGDLADLGEPDAYRRLRAAIEPVAAELGAPVVWVAGNHDERPVLREVLLDAEPTE
EPVTGVWDLDGLRLVALDTSVPGWHHGDLDPAQLAWLAEVLAEPAPHGTLLAMHHPPLPS
HLPLFDILELRHQDELAAVIRGTDVRGILAGHLHYSSHGLFAGVPVSVASATCYTMNVAR
PASEVNGMDAAQAFQLVHVRPETITHTVVPVVDAPTGDYFSEEWVARMAALTPEGRLEAF
SRKPPQGPA
>A0A1X1CXA4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea rwandensis|TrEMBL
MDSLLTLPAANGADIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIMAQQRDYDLTI
ATGDLAQDHTVEAYQHFVAGITRLPKPCVWLPGNHDFQPAMVDTLADAGIAADKHVLLGE
HWQMVLLDSQVFGVPHGMLSEYQLEWLDIALRKHPERHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLHHFPRARNLVCGHIHQELDLDWHGRRVLTSPSTCVQFKPHCTNFTIDNVA
PGWRWLTLKADGSLETEVNRLQSDMFRPDLDSEGY
>D4F064|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Edwardsiella tarda ATCC 23685|TrEMBL
MESLFHLAVASGAPVRLLQITDTHLFAGPQETLLGVNTYRSYQAVLAAIRAEAQPFDLIV
ATGDLAQDHSSAAYHHFAAGIATLQKPCLWLPGNHDFQPAMVDALAQAGVQASKRALLGD
QWQIVLLDSQVVGVPHGELSDYQLEWLEQALLSEPQRHTMILLHHHPLPSGCTWLDQHSL
RNAHALDEILRRHPRVKTLVCGHIHQELDLDWNGCRLLATPSTCVQFKPLCTNFTIDTIS
PGWRYLDLYPDGRVTTAVHRLAGNEFRPDLDADGY
>E2C088|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Harpegnathos saltator|TrEMBL
MASPPNRYFFPSDDEDSLEDELYGNGKTDVLDIVGEKTPFEGNDEGSDYLTILYFLNKTL
EMMRQSTQPVLYVSSAIDDNNVYKEEPRTWYNNIFNVMCGCMRKECCATNRMQVTESTPT
ELQLVKIIRKGPQDVNTHLLTTSVPNIVKILLVFSKDDQQMEILATTASKLGWSVSVAKD
AEKAIELFQNRTHELVIIDHRGHRATEGDAICRALRSSPVHHNSVIIALVKKSYFMLADK
DHIAALNLLETGFSRAMMECSHEGILINELVGIYTSSLLPRTQLAAAHALYLALDRCRDM
VHVTNDKNIVQFLNKVSEKLLGYATEEMMGRNLSEIVFYENFALMEQQLSKGREFEGNMN
CKRKNNQMITINCRIIPFCTTLKKPTHYIYVYDTTYLSENIAPISPIASPLHPPLRTSIL
SNTRKPSDVRSAVSEGRRRSSLQKLHTLQLEAPITKVITLLSNAVTDSTNPETAAQIDKV
IDILKTTELYVPHLKEDKIYNDPVATDLVGALLSSSRTTWDSRRSSADSARLSTIRPITG
PTNARMSMKNFRGPQEIADVLDNSLEWEFEIFKLEVLTEGRPLVFLGSTIMNLYQVPAKL
NCDEKVMQNWLSIIEYNYISENSYHNSTHAADVLQATATFMQSKRLKEILEPLDEVAALI
AAAAHDIDHPGRSSQFLCNASNRLAILYNDLSVLESHHAALTFKLSLSDDNVNIFKNLDR
DTYKLLRQNVIDMILATEMTKHFEHLAKFMNVCSARIGDGQVESYSNSLDMSVILQPDNV
ILIKRMMIKCADVSNPTRPLKSCVEWARRIAEEYFCQTDEEKKLKMPVVMPMFDRQTCSI
PKSQIGFVDFIINDMVEAWDAFIDMPEMVGYMRQNYEKWKEYNEQGISTLQDVEKIQQHP
DLQIPRLSR
>A0A7Y7WF57|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas gingeri|TrEMBL
MPSEPTQSTPADAVLLVQLSDSHLFAEADGTLLGMNTRDSLQRVIDCVLAEQPGVDLLLA
TGDLSQDGTVASYRQFREMSEVIGAPTRWLPGNHDELPEMAEAARHSDLLEPVVDIGNWR
IILLDSAVPGSVPGYLQDEQLQLLAQALSEAPQRHHLVCFHHHPISIDCAWMEPIGLRNP
EALFAVLDRFPQVRALLWGHIHQELDRERNGVRLLASPSTCVQFAPGSEDFKVDDKAPGY
RWLRLHSDGRLETAISRVRGFDFEVDYGGTGY
>A0A2D4L507|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micrurus paraensis|TrEMBL
MLSSCSKLHNSPGVSSPSMTGSSPVQSKKTSMIPNLRLQRRFTVAHPLCFDVENGFSPGR
SPLSSQTNLGLGLVLQGTTPHSQRRESFLYRSDSDYDLSPKAMSRNSSISSDMHGEDLIV
TPFAQVLASLRTVRSNFAVLTHLREHVCNK
>A0A6S7D3S6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter pulmonis|TrEMBL
MTRILQFSDTHFGTERKPVLEAALDLARTLAPDLVVISGDITQRARRGQFAAARKFIERL
SLPVLAVPGNHDIPLFNLFARALNPYGNYKRALGAVLEPVYETGGLLAIGVNTTRPRRHK
DGEISDTQIARVAQRLRQARPGQLRVVVAHHPVRAKVESDRFNLLIGRERALAAWAEAGV
DLILGGHIHLPYVLPASADPALAAGWAVQAGTTCSRRVRGNIPNSVNVITRQGEGETRTC
HVERWDYADATHAFAPVDKTLVTG
>A0A6J1MAI6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila hydei|TrEMBL
MIISSQPANLSGTSSAHMSEEGVESDCSCVGVAVAVGESAATTTAGAGTGAGVGLMMGRA
ARQMQTHAMEAEKPPTPPPPPTPATATTTTTTTAAKTTTHRASLTRPASESELLVGTGTS
GTSSSGGGRPGHRKSSLALALTPEDDSMDVYQRNLMDLKYPTVLPPNPQLKALLVFHKSD
SICEVVTLACQRHQLDVTLVKSKEEALETLHKSYATAQCYHLIIIDARSTKGLDAEHIAR
TIRHTHGHHLTTIIAVCKKSFFEKDDALIALLDAGVNRCIAETTNLTLCSVELKQILHSI
IRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLNMRLDEIISKPLGDIF
VSDLSTISEQGKSIKEFDGILMVRRKNQESIPMHVRVVPVACIGSAPTHLIFNFDIPGGG
MDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLL
SQVQENCSADEARLIDKVLDFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRR
SSNDSIIRTGNSTRTATIVPAKMKANPIIMELLEESLKWDFDIFKLEEITDYHPLLYLGM
EMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADVMQATGAFITQLASKD
MVMDRMDEATALIAAAAHDVDHPGRSSAFLCNSNNPLAILYNDLTVLESHHAAITFKLTL
GDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGNEMEPRELVQSEE
ETSILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYFMQTDEEKQRHMPIVMPMFDRAT
CSIPKSQIGFIEYIIQDMMHAWDGFIDMPELITCMQINYSQWKKYDEQGVNTLADIMAKQ
PPVGNKSSSSK
>A0A6J1MK20|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila hydei|TrEMBL
MGCSPSTLPNSSSTAGGAGGVGNAPLPPLDANEKDGSLLFCIKLRRSRMRRCSCGAVTLQ
NQNGDGSTGSATCGDNMMCNQGLLNPLQTKNESDYEKLSTGKKDSIVTVAALGNFTHSVV
RRATGTGSTGTSGTSSSGGGRPGHRKSSLALALTPEDDSMDVYQRNLMDLKYPTVLPPNP
QLKALLVFHKSDSICEVVTLACQRHQLDVTLVKSKEEALETLHKSYATAQCYHLIIIDAR
STKGLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDALIALLDAGVNRCIAETTNLTL
CSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLNMRL
DEIISKPLGDIFVSDLSTISEQGKSIKEFDGILMVRRKNQESIPMHVRVVPVACIGSAPT
HLIFNFDIPGGGMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLP
LEAPITKIINLLSQVQENCSADEARLIDKVLDFLKREGLYSPQMKEIRTDDPIATDLIGA
LLTGPSVYSSRRSSNDSIIRTGNSTRTATIVPAKMKANPIIMELLEESLKWDFDIFKLEE
ITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADVMQA
TGAFITQLASKDMVMDRMDEATALIAAAAHDVDHPGRSSAFLCNSNNPLAILYNDLTVLE
SHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGN
EMEPRELVQSEEETSILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYFMQTDEEKQRH
MPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWDGFIDMPELITCMQINYSQWKKYDEQ
GVNTLADIMAKQPPVGNKSSSSK
>A0A2D0JRH1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus miraniensis|TrEMBL
MESLLEIPVAEGATARILQITDTHLFANKGDSLLGINTYRSYHAVLDKILEQNLDIDLIV
ATGDLVQDQTINAYQHFAEGIARLPAPCVWLPGNHDYQPAMVDTLAAAGISPSKQIFIGQ
HWQLIMLDSQVQGVPHGELTDYQLEWMNKCLDKHSERHTIVMLHHHPIPSGCTWLDQHSL
RNAPELSEFLKGRTQVKAILCGHIHQDVDEMWNGIRVMATPSTCVQFKPHCTNFMLDTVA
PGWRYLELSVAGNKEASLQTQVHRLKSNEFCPDLDSDGY
>A0A6L8BEN8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteobacteria bacterium|TrEMBL
MTSTRSHRPASVPAGDTAGHPAGGAATCPADDAAGLTVVLLQITDTHLFAAVDATQRGIN
TQSSLDAVLAHARSDTRWPPDAIVVTGDIVHDESRVGYLRFRKILESLGPPVFCVPGNHD
DPEVLAECLVTPRVQVCGDTQLGTWRVILLSTFGEGEVAGALGSAELARLEATLEEYPGE
HTLICMHHPPVPMGSAWLDTPGLRGAGEFVQLVRRHAQVRAVLWGHVHQASDRHVDGVRF
MSTPSTCAQFRPHSDEFSVDGLTPGMRWLMLNPDGSLTTEVVRIGIG
>A0A5W0WMF4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Albany|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>N6TN97|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dendroctonus ponderosae|TrEMBL
MAQHATCQAMYTALDKCRDLVIVTDDSYKFQYMNAACERQLGLRQEDTIGKTLQEQLVYD
TVQINTMGSSLLRAREWSGPMTLKRKSTQETIVSNCRAVPFSCAGRMPTHFILVFDTNSI
DPSNLSQSRGSIHSIRRGSTDVRSIGSDYLRRTSLAKLNALPLEAPITKIVGLIDQIREN
VGSNGQLVQLIDKVEDILKGSELYVSHVKEDFRMKTDEPVVSDLITALLSKAPQPTVTAS
SRRSSNDSSVFRPSRTGLIKVPAAIRDLLDTALMWEFDIFKLEDLTRKRPLQHLGMNLFN
HFDVCGALNCDERTLSNWLTVIEANYHAENSYHNSTHAADVMQATAGFLEKERMKSIMEP
LDEATSLIAAAAHDLDHPGKSSAFLTNSNNPLAILYNDVTVLESHHAAMTFKLTLGDERV
NIFKNLDRDTYKLARHNVIDMILATEMTKHFEHLAKFVNVFCTRSSVGSEIGDQSEDYAP
ILTAENTTLVKRMMIKCSDVSNPTRPLRLCVEWARRIAEEYFQQTDDEKARGLPVVMPMF
DRQCCSIPKSQIGFVDYIINDMFEAWNAFIDMPELLTYMRQNYIRWKEFDEQNHTTLNDI
QKLQATILAPSITSSHSVDISDLRYIITQRTMNRNTYLTK
>A0A6P8LV55|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bombus bifarius|TrEMBL
MGCKTSMLECIEDTGEAEKRKHSDMVNQGSLLGKTEYDVLRRRSSFEDVAVDDDENADCS
ALKGPQNIEAHPLTNSVPSLIKILLVFPKDDQQMDVLATTSRRLGWSVSVAKDAEKAVEF
FQNRGHELVIIDHRGQRAAEADTICRYGELFFKNQPNSSGVRLYILINTIYFRAIRSSPA
YHNSIIIALVKKSFLMHGEKDKIVTLDLLETGFSRALMECSHERLLINELVGIYASALLP
RTQLAAANALYVALDRCRDMVHVTNDKHIVQFVNKISEKLLGYKTSEILGKSIADIVVYD
NFVLMEQHISKGREFEGNMNCKRKNNQMITISCRVIPFSISLKKPTHYIYIYDTTYLSEN
IGSLSPTPSQSVYSRGNMIVSQRRTSDMKSSEGRRRSSAHKLHSLQLDAPITKVISLLSN
AITESTTPDTAAQIEKAIDILKTTELYVPSLREDTDPVTTDLVGALLASPRKAWESRRSS
VESTRVSMSKAFTTTTSSRMQIKSFRGPQEIAEILERCLEWNFDIFKLEILTEKRPLLFL
GTTIMNMYRVPARLGCEEKVVQNWLTVIEMNYQSRNSYHNSTHAADVLQATARFMQSERL
QQILEPLDEVATLVAAAAHDVDHPGRSSQFLCNSDNKLAILYNDLSVLESHHAALTFKLS
LSDDNVNIFKNLERDTYKQLRQTVIDMILATEMTKHFEHLAKFMNICSARMMDSPQLDDY
TDTVDMSVVLQPENVVLVKRMMIKCADVSNPTRPLKCCVEWARRIAEEYFNQTDEEKRMQ
LPVLMPMFDRATCSIPKAQIGFVDFIINDMVEAWDAFIDMPEMVGYMRQNYEKWKEYNDR
GISTLPDIEKIQELPELRIYHLPS
>A0A380Z675|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Phocaeicola vulgatus|TrEMBL
MMLIKLFLFFLLLLILPDMYIYKAYIRRVSQKWTHWAYWLPSLFLLLGMTLVFSIHEPRP
DSMQRLSNFLLIFLCFSVPKALFVIVILFMKFLYIISGKKLYGGYVAGGLALASLIYVIY
GATEGKQHFQIREVTISSDELPSGFDGYRIVQISDIHSGSWTGNGAALQKAVNLINAQHA
DLVLFTGDLVNNVATELDEFIPILEQIKGKDGVYSVLGNHDYSPYIKWETEEAQEANLNS
LKSKQAAMGWKILNNDHVILHHHGDSIALAGVENSGNPPFPNYGDLQKALKGTEGMYKIL
MSHDPTHWHREVLPESDVQLMLSGHTHEMQFSLFGFSPAKFVYPEHNGLYQEGKQSLFVN
IGLGYLMFPMRLGAWPEITVITLHKI
>A0A137PNH9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lactobacillus johnsonii|TrEMBL
MKIIKKTKGMIDKFSGVTRKMMRKKSNIPFDGMQKYMTVGEYNVGAPEGTPHGEEYKLIV
YKDTDNVLHQALRSINASDLAPAYVRKFDKRLNRYTAFVNKQTGRRYIVEDQLDQLVDYV
KKHSRDGYNSINIGVLTDTHYKDADSIDFYGHNGLRHVKEFNYLEDKDVLDLKAHLGDWM
DGSDPGLVGEAELISLSRTFRSKKTNFAVIKGNHDENDKFDEHHDLRASFPENEFEDIMW
PSMYAQDGIHYITRKHGVAYFDKDDVRIITVNTSDLPYELDEQGKKKYDTKLALAIREDQ
MQEIIEILENSNGKTIIFMSHANPITRKGTNALKFNGRSLHELMVAFNQREKGYLNSRDV
PPEFTLANSFDFTKIKNAKIVAYLCGHRHTEDQYRINGIQYIFFNCSALMGPNHALTTQY
NKRWNRQMDHANEAAGYIVNVDVQRHLLQVFGYGAASKRRFYRI
>A0A2N7WUQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia rhynchosiae|TrEMBL
MKIRVLSDLHLENDEPELIPHAQADLIVLAGDIHNHAAGPRWVAQTFDGTVPVVYVPGNH
EYYDGEFGALESALYDAAAQVDNVHVLNNAALADPQGRWRVLGTTLWTDFALYGADSAAL
TESIEASRRAMLDFRGLIQMNWPHDTHDAPRDFTPDDCLALHRQAREWLEGELAKPFAGK
TIVVTHHAPHRLSLAERYAQDRVSAGFVNHLPELVRTPVTLWIHGHTHTPFDYTVNGTRV
VCNPRGYFDRRSRQWENPLFEWDKVVEI
>A0A2X0RL45|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lactococcus lactis|TrEMBL
MTKKRRLAVISDFHMDSNHFSQEEIDIFLSLLKDLKITDLHFAGDISNDFHGISEPFFKQ
IELLTELSVTYNLGNHDMVGLSEEEISVSNFQVKTFASTAFVSFHGWYDYSFMTGKIDIK
KIIAFKNSFYFDRKIHRQFDDIKITNLELQKLEKLLTELSANPKIDRIIVSTHFVPHQQF
IINTRYEKFARFNAYLGSQHFHENFKKFPKISDVIFGHLHQRRLPLTFDKVLYHAHPLGY
PYE
>A0A1W4U9K6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila ficusphila|TrEMBL
MIISSQPNLVGSATTTTTTTNAHMSEESVPSTCNCGGGGVAVAMAVGGGVGGVVALGARQ
SPVAEPTTTTATATTTVTATTILKTPTSTAAGRDSLTRPASESELNVGTGTSGTSSSGGG
NSRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLVFHKSDSICEAV
TAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSTKNLDAEHIARTIRHTH
GHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNV
MSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSDLST
ISEQCKSIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQMDFIAT
LPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQEN
CSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTVTKGPSVYSSRRSSN
DSIIRTGSSTRTASIVPAKMKSNPIIMELLDESLSWDFDIFKLEEITDYHPLLYLGMEMF
RRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDMMM
MDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLGD
DKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPRDHNSQTDEET
SILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRATCS
IPKSQIGFIEYIIQDMIHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLAEIMAKQPP
VGKMANSK
>A0A401ARB8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella senftenberg|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A7I6WT26|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter freundii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEFDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSSLQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVCRLQGNRFHPDTASEGY
>A0A3V9PYI4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Bredeney|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>B0NEF8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clostridium scindens (strain ATCC 35704 / DSM 5676 / VPI 13733 / 19)|TrEMBL
MKLGVISDIHLDVNEQYPVVELLAKEAERRKLEGLLLAGDISNGPKSTLRHLEQMKKRLP
VPFWFVPGNHDMWDQEQEYMDSWQIYEEYKKYEECLCGKSVQVGNSILLGNIGWYDYSFG
DEAYSIEDFQKKSRNGRVWQDSIWVRWNRDDRQLAKAMCEELEEIIKEHKGKRTISVTHM
IALPELKVPLERVNWDYFNAFLGSRELGEMYERNGVSCAVMGHVHYRKRILKNQVDYVCA
CLNYHTEWQTQDPGEELRKTMQEIEA
>A0A265B377|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Heidelberg|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A498TZC0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacillus safensis|TrEMBL
MKQLSRRQFLKGAAGASILGFLATSCGYGYARYIEPRMIDTVSLTIQDAQLPASFDQFKI
AQFSDVHLSDTFAAKNLEAIVQKINAASPDLIVFTGDLVDFQASSEEHEKAKAYLNKLHA
PFGKLAIYGNHDYGPFGVELYEKTMEACGFTLCKNDVFLLEKDHAHIQIASLDDLMMSVP
DYDLIKREVSTDLFTLLLVHEPDAALELKTTPINLQLSGHTHGGQVQLPFYGPILTAPYG
RTYVEGIYGSDQHRIYVNRGLGTTRLPLRFLAKPELTFFTLTSRV
>A0A3Q9MFJ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Karamoja|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A4Y6M7E2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Indiana|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A753A613|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLVNFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A418PJS6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Veillonella parvula|TrEMBL
MRILFNIIFSAILAIGLVGFWALFLNLWKPKKKWPAWVGYIIIIGAWFAAIRYYILNQVD
LYGTMYYPLMNMFRTESYGFLFGVFLAIPVFIILSLLYWTINKIWSKTPEENRTGRRAFF
RTAATIVPLATIGGSSYAAFAGQQEVVVTHESFGYTNLPPGLKNYKIVQLSDIHIGPSID
LDDFDEILKLALLQKPNRVVITGDLIDKLAWLPQVCERLTTFAKQIPDGVDFILGNHEYH
HDVNKVLDALKRNTPMNILVNSNIQIMGGKQPVYIAGVAYDNDRKKDNREAMINKALSGI
PDYAFVILLAHHPEFFEESIERKIPLTLSGHTHGGQIVFMGMPLVPTGTPYTKGRYVEEQ
SVCYVNNGTGHWFPIRINCPREITVITFFDGVA
>A0A5M9ICU0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas panacis|TrEMBL
MLAALIDPASVNLPLNPQGQRLRIRIYSDLHAEFHRFAPPSLDAGVDLVILAGDINKKAR
GVQWANDTFACHVAYIAGNHEYYDGHIDRTLQKMKGAAAGHVHVLENEALILGDVRILGT
TAWTDYSVTGDLLAASNAARQGMNDFKYIRADSNYRRLRLDDLVTRNHIARDWLTQELAR
PFDGKTVVVTHHSPSPVVIGEQHDGHLTAAYTNDWPRLIEKAHVWVFGHTHEATDVELAG
CRVVSNPGGYPGESTGFDPYFEIQI
>A0A5S9MY49|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|BD1-7 clade bacterium|TrEMBL
MPLKVLQISDCHLPDVAGDTLLGLDTEMTLKRVCEHAFAHHPTPDLIALTGDITNGKEDT
AYHMLREHLPKDVPLAWLPGNHDNNRVMQPVVGDEFLPSLTIGNWCLTFLDSSIDGAVPG
LLEDGEVQRLDSVLRGAPDKHHLIFMHHHLKPAGCAWLDTQVVKNAPHVLGLMAGFRQLK
AVAHGHVHQAFEQKHAHFDILACPSTCFQFKPLSDNFALDDKMPGYRYFELFDDGSYISR
VERIEYIELPIDHKAGGY
>T0P8K6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus temperata subsp. temperata M1021|TrEMBL
MESQFKLPVVEGTTAKILQITDTHLFAGKEETLLGVNTYRSYHAVLDAILKQNADIDLIV
ATGDLAQDQSLEAYRHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGE
HWQLLMLDSQVPGVPHGELSEYQLEWMKKCLDMYPERYTVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQGYTRVKAMLCGHIHQEMDLDWNGIHMMATPSTSVQFKPHCTNFTLDTVA
PGWRYLELSISDRGEFSLTTQVYRLESNEFCLI
>E6BF70|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli MS 85-1|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A6J0X1Y8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Odocoileus virginianus texanus|TrEMBL
MSLPTSCEYLTLGKMARFRSPAYVHGSPYATNKPIDIKPQRRRFDVDNGTSSGRSPLDPM
TSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQV
LASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATLTEEAYQKLASETLEELDWCLD
QLETLQTRHSVSEMASNKVSPGSVLTQAPRLLIPTLVKPSVPVDPGNRGLSHTLHFGSLG
RRFLVLPVPSLSHPFTLEKLNILQKQL
>A0A5M8GAH7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas lactis|TrEMBL
MPSVSAVNPDAVLLVQLSDSHLFADPDATLLGMNTRESLQRVVELVRAQQPAIDLILATG
DLSQDGTLESYQQFRALTASLGAPARWIPGNHDEPQVMAQAAMHSDLLEPVVDIGNWRIT
LLDSAVPGSVPGYLQDAQLQLLAQALSEAPGRHHLVCFHHHPVPIGCAWMEPIGLRNPEA
LFAVLERFPQTKALLWGHVHQEIDSERDGVRLLASPSTCIQFAPGSEDFQVSEQAPGYRW
LRLHGDGRLETGVERVKGFAFTVDYGSNGY
>A0A2I8Q013|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacteriaceae bacterium ENNIH1|TrEMBL
MESLLNLPLAGGARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIQAQQRECDLIV
ATGDLAQDQTAAAYQHFAEGIARFGAPCVWLPGNHDFQPAMYTALQEAGISSSKRVITGD
NWQILLLDSQVFGVPHGELSEFQLDWLEKKLSASPERHTLLLLHHHPLPSGCSWLDQHSL
RNAAELDNVLARFPHVRYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLYPDGSLQTEVCRLQSTRFNPDTASEGY
>A0A3E1SP43|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella oxytoca|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQILLMDSQVFGVPHGELSDFQLEWLEQKLAEVPERYTLLLLHHHPMPSGCSWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLDLHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A2D4LE75|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micrurus spixii|TrEMBL
EMVQRPTNLPLRTLPLIAITAADTDTVSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVH
SQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALT
NLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMA
SNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKLPMSQI
SGVKKLMHSSSLTNSSIPKFGVKTDQEDILAKELEDVNK
>A0A0B8QIU2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio ishigakensis|TrEMBL
MEPRIVETGESVQLVQITDTHLFEDSEGTLLSVNTEHSFHAVVEDVISKELAFDAIIATG
DISQDHTAASYEKFVEGIKPLVKPCFWLPGNHDYKPSMGSVLPSAQIQACNHFLAGEKWQ
VILLDSQVTGLPHGYLEQEQLAYLDDKLAEYSERHSLVLLHHNPLPIGSAWLDQHKLQKA
VEFWQVLDRHKNVRAVLCGHVHQEFQTEHHGVQVLATPSTCIQFKANNDEFALDNLSPGW
RHLSLHSDGSIESKVYRLPDGSFVPDFEAEGY
>A0A653Y0K5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arthrobacter sp. 9AX|TrEMBL
MEHIEAEHPRPRHFLLHLSDPHLLGGPDPLYGVVDSEARLSQLFEEVKASGARPEAVIFT
GDLADKGDPEAYVKLRAIVEPACLELGAEVIWAMGNHDNRANLRKGLLDQPGNDDPLDHS
YFINGLRVITLDTSVPGFHHGELDDAQLDWLAQELDTPAPDGTILALHHPPVPSVLDLSV
LVELRDQASLAAVVRNSDVRTILAGHLHYSTTASFAGVPVSVASASCYTQDLNVAVGGTR
GQDGGQSFNLVHVYEHTIVHSVVPLGSSTTVGEYVSPEETERRLAAAGIRIPETAKQSSS
GKIGLRTGR
>A0A0J5Y161|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium peruviense|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIEARQDAFDLIV
ATGDLAQDHTLQAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSAVLDRYPKVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDNVA
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A154NZK8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dufourea novaeangliae|TrEMBL
MLQKRPQDIDAYPLTNSVPSLIKILLVFPKDDQQMDVLATTSRRLGWSVSVAKDREKAVE
FFQHRGHELIIIDHRGQRAAEAETICRAIRSSPVYHNSVIIALVKKSYFMYGEKDKIVTL
DLLDTGFNRALMECSHEGILINELVGIYTSALLPRTQLAAANALYVALDRCRDMVHVTND
KHIVQFVNKISEKLLGYKVSEMLEKNIAEYVHYENFVVLEQQISKGREFEGNMNCRRQNS
QMITINCRVIPFCSALKKPTHYIYIYDTTYLSENIDPLSPLPSLAQTPFSKTVSVAVAAT
SQRRASDVKSSITEGRRRSSLQKLHALQLEAPITKVITLLTNAITDTTSPDTAAQIDKAI
DMLKTTELYVPYLKEDRNYTDPVATDLVGALLASPRRPWESRRSSAESARLSTLKAVTTA
PSSSRMQIKGFRGPQEIAEILERCLEWNFDIFKLEVLTERRPLLFLGMTIMNLYRVPARL
GCDEKIVQNWLAVIEMSYRAQNSYHNSTHAADVLQATARFMQSERLKQILEPLDEVSALI
ASAAHDIDHPGRSSQFLCNSDNKLAVLYNDMSVLESHHAALTFKLTLSDDNVNIFRNLER
DTYKHVRQTVVDMILATEMTKHFEHLAKFMNVCSMKVGDPGDGYIDSMDMSVVLQPENVA
LVKRMMIKCADVSNPTRPMKCCVEWTRRIAEEYFNQTDEEKKLKLPVLMPMFDRQTCSIP
KSQIGFVDFIINDMIEAWDAFIDMPEMVGYMRQNYDKWKEYNMSVVPLMFRDWWDDFDRP
VSRIMDQHFGRAVDRDDLISRFSELSSLERPMRSIFGNRYYRPWRNAVTRQQSSGSSTIQ
IDNQNNFQVILDVQQFSPEEITVKTVSNNIIVEAKHEERQDEHGYVSRQFVRRYVLPPSH
DVINITSSLSSDGVLTITAPKKGETPSGGERVIEIVKTGEPASKPVNVDTTD
>A0A443IBE4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|[Pantoea] beijingensis|TrEMBL
MNSLLKIPVASGAKIRILQITDTHLFAGKNETLLGVNTWASYDAVLEAIQAERCHYDLIV
ATGDLAQDHTVEAYQHFAEGIARLSAPCVWLPGNHDFQPAMFSTLAEADIADAKHVLLGE
HWQVVLLDSQVFGVPHGMLSDYQLEWLENTLSLYPQRHTLVLLHHHPLPSGCNWLDQHSL
RNPHALDAILQKYPLATTLVCGHIHQDLDLHWNGRRILATPSTCVQFKPHCTNFTIDSLA
PGWRSFDLFEEGRVETQVHRLQTQHFSPDLDSEGY
>A0A077QGV6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus bovienii str. Intermedium|TrEMBL
MESLLKIPVAEGATARILQITDTHLFASKGDALLGINTYRSYHAVLDAILEQSIDIDLIV
ATGDLVQDQTIGAYQNFAEGIARLPVPCVWLPGNHDYQPAMVDVLAAAGISPSKQILIGQ
HWQLVMLDSQVQGVPHGELTDYQLEWLQKCLDEHNDRNTIVMLHHHPVPSGCTWLDQHSL
RNAPALAESLKDKRQVKAILCGHIHQELDKMWSGIRVMATPSTCMQFKPHCTNFMLDTVA
PGWRYLELSVADNREAKLQTQVHRLKSNEFCPDLDSDGY
>A0A418Y0J7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alcanivorax profundi|TrEMBL
MVTNSGSWTGFLEKCHHLGYKESQEGVGTPERACALNHGNQKNHHGHGSGDLTQQLQPLR
VVQLSDCHLFADTDGKLLGLNTQFSLDKVLELIRLEQPNPDLILATGDLSQDASFESYQR
LDQALADFNTPVYWLEGNHDKPAPMLEALDTQRERMSPCVLEVGNWTIVMLDSTIPGEVP
GELFDEDLKFLDQSLAHAKGDHLMVCLHHHPVPMECAWLDTQVVGSASQFFDVIDRHDRV
RAIIWGHVHQEYDNERNGVRMLAVPSTCVQFKPKSEDFAVDDTNPGYRWLDLHPDGRIDT
GVSRVEGITFEVDFTVKGY
>A0A672V8G1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Strigops habroptila|TrEMBL
MINFSEEFYYFQNSYVNGINLFILSFCSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVH
SQRRESFLYRSDSDYDLSPKSMSRNSSIASDILKLFCLFQVLASLRTVRNNFAALTNLQD
RAPSKRSPMCNQPSINKATLTGKN
>A0A0F4P128|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio neptunius|TrEMBL
MKVTSSSSDSSIRLLQITDTHLFEAADGSLLSVNTGDSFKAVIDAIVEENPAYDAILATG
DISQDHSEASYQRFEKGIIPLKKKCFWLPGNHDFKPSMTSVIPSPQIQQIEHALLGEQWQ
MIVLDSQVAGVPHGRLSDKQLMLLEEKLAQYPQRYTLILLHHHPILVGSAWLDQHTLKDS
EDLWQILDKHNNVKAVLCGHVHQDMNVVRKGVRVMATPSTCVQFKPHCDDFALDNQAPGW
RELLLHDDGTVETEVKRLPVGSFQPDFHSTGY
>A0A427F9Z1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. o96-267|TrEMBL
MPSLPAPSTESSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIERVQQEQPQIDLILAT
GDLSQDGSVASYQRFRQLTSAIAAPARWLAGNHDETPPMQAACKDSELLEPVIDLGAWRI
TLLDSSIPGAVPGFLADSQLELLERALSEAPQRHHLICLHHHPVSIGCKWMEPIGLRNAD
ALFAILDRYPQARAVLWGHIHQEFDQIRDNLRLLASPSTCVQFAPGSEEFQVGSDAPGYR
WLCLHADGRLDTGVSRVTGIDFEVDYSVKGY
>A0A6C7I4H7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella paratyphi A (strain AKU_12601)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPCVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A498QGG7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mycobacterium innocens|TrEMBL
MHRLRAAEHPRPEYVLLHISDTHLVGGDGPLYGAVDADGRLGELLDQLTHSGLCPDAIVF
TGDLADTGEAQAYRKLRAEVEPFAAELGAELIWVMGNHDDRAALRSFLLDEAPSMAPLDR
VHMIDGLRIITLDTSVPGYHHGELRRSQLSWLATQLATPAPHGTILALHHPPIPSVLDLA
VTVELRDQAALGRVLDGSDVRSILAGHLHYSTNATFVGIPVSVASATCYTQDLTVAAGAT
RGRDGAQGCNLVHVYQDTVVHSVIPLGSGKTVGTFVSPAQAKRQIAESGMFIEPSRRDSL
FSQPPMVLTPAARPGPAR
>A0A6L5NUL6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. XMDDZSB0408|TrEMBL
MQREPKNYSTMKNDSVRLVQMTDPHLFADPDSQLLGVNTANSFNAVMDTFLANGHHADLL
LATGDISQDYSPESYHDFTEYVTKLDLPCHYLPGNHDDPRLMSLHMQGAHMFGQQLITIG
DWQIIMLDSTLRGKPSGYLNDSQIELIDFAIKKSPHLNVLLCMHHNPVLVGCKWLDQHCM
ANGSEFLETVSQYPQVKGILWGHVHQTYEQQYQGQHGKIALMATPSTCIQFKPKSSYFAL
DGVQPGYRLLDLHSDGSIHSQVYRVPGDHFTPDNEASGY
>A0A4Y7RJG7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pelotomaculum propionicicum|TrEMBL
MRLVYLSDTHIRGSRPEYRQDDFLGAIHTKLSEVVKLCRQLNVDFVIHGGDIFDTPRPDQ
PSFDLFRWFLKELGVPVYCVAGNHDLVEQRLDSLETTAIAFLDRQRLLTLLKPGEKLYLS
NNSCVLQLSGQHFFAGIDRRRSKNGYVVTKKRCDIAIHVVHGMLLPKQFSEKVPCTLISE
VARTEADFTLGAHAHLGYHEYSGVKYFLNPGALARLTNLKQELVRIPRILYMDFTGPASY
KFISLENVRPGGEVMNLKKPVK
>A0A5C7R2A5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Tolumonas sp|TrEMBL
METCTLNNTGDGIVRLLQISDTHLFADSTRDLLGIATADSFQAVLDAITELPQAYDVVLA
TGDLSQDHSAESYQRFARMASVALPKPIHWLPGNHDHRVLMQNELHAAGIRPEMQLVSEH
WQVILLDSQVYGTPHGWLSHLQLEQLEAALQQHPEKHALICLHHDTFPIGSIWLDQHDLK
NANDFLAVLARYPQVKAVVCGHVHQEYDQYHQGIRFLTSPSTCIQFKPLSVDFALDTMSP
GWRYLQLYPNGEIATQVWRLAPGQFTPDLESTGY
>A0A7L9R923|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dickeya dianthicola|TrEMBL
MESLLTLPVARGARIRILQITDTHLFAGERETLLGVDTYRSYQAVLDAIVAQPGDFDLIT
ATGDLAQDHTQDAYMRFAEGIRRFNAPCVWLPGNHDFQPAMVDVLARLGIAPSKHVLLGE
HWQVILLDSQVFGVPHGELSEYQLEWLERSLQSQPERHTLLMLHHHPLPSGCSWLDQHSL
RNAHSLDALLLRFPRVRTVLCGHIHQEMDLDWNGRRLLATPSTCVQFKPHCTSFTIDNVA
PGWRSLELLPDGGVETQVYRLEGNEFLPNMDSEGY
>A0A5J4QP83|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MIQAQNLPRFAVISDTHFENNIGEGAAVKVPRALKNLLWKQPQPDAIFVVGDITHRGRLE
QYAQLLSVFGDSTNVPKGTAVYFMMGFQHDRSGSIHQENYLLGTHQPLHQYIDIKGYPFI
TISEGGRHPSEYNESVKKWLAEKLEDAAKNYPDKPIFVFTHIPPLSTCYGSAPGAWGTDM
FSEILNKYPQIVIFSGHSHYPIGDPRSIHQGIFTAVNTGSTSDSNVAKGILVKGEEPPLN
DRVTEGLLVDVLSNGNIEIERWDTYRNEEILPRWLVQAPHDGTKFTYTDNRNGLPAPVFA
PGATPKVTLEKDSCLVSFAQATDNEVVQHYAIEITDGTEVIASNKVFSLFYLNSQMPGIL
SAKFGALPAGKKLRARIVALDSYGNPSLPIQSKAFKVKPACKSCAKEHD
>A0A5J4RR00|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MKKYFILISTVVFYFVACQSTSTPERIRLKFNSEGKFKIAQFTDMHIINHSPNTAKTFAT
IKYVLENEKPDVAILTGDIVIRRPSREVWPLLAQLFEEAQIPFTIVFGNHDVETITRDSV
FDILSHSPYFIGEKGPENIHGVGNYVLPVYGSTSSKPSLLLYCLDSNAYTEYKQFGPYCD
DWIHFDQILWYREQSKQFTQSNNNQPLPALAFFHIPLQEFNNIVGKETTVGTKGENNTPG
KVNSGMFSSMVDMKDVMGVFVGHDHDNDFIGMEYGIALAYGRVTGVDTYGKMERGARIIE
LNESKPCQFTTWIRTPKGGIEHTYYYPSGVTKFAEETAIYQPSLPVNPTKQGVSYSYYEA
KFKSVDEIATAKATKQGTQNNFSIKDAASADSFGYEFRTWINIPEKTLYYFYTRSDDGSK
LLIDGNLIVNNDGSHGTKRAVGSVALESGFHELCLRYFEDFREKELEVGFSSKNILETVI
PDNILFIPE
>A0A2D0J3M2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus budapestensis|TrEMBL
MERLLEIPVAKGATARILQITDMHLFANKGNSLLGVNTYCSYHAVLDAILEQNLDIDLVV
ATGDLVQDQTIGAYQHFVEGVARLSAPCVWLPGNHDYQPAMVDVLAAAGLPLSKQIFIGQ
HWQLIMLDSQVQGVPYGELTDYQLEWMTKCLDEHSDRYAIVMLHHHPVPSGCTWLDQHCL
RNAPALAEFLKDKPQVKTMLCGHIHQELDDMWNGIRVMATPSTCVQFKPHCTNFMLDTVA
PGWRYLELSVTGEGEAKLQTQLHRLKSNEFCPDLDSDGY
>A0A3N3E4I8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio ponticus|TrEMBL
MKVTSNTSVKETIKLLQITDTHLFEAEDGSLLSVCTNESFKAVVEAVKQDGFEFEAILAT
GDISQDHTDASYQRFAEGIQPLQQPCYWLPGNHDYKPSMGTVLPSEQIVQVEHELLGEHW
QMILLDSQVEGVPHGRLSQQQLDLLEAKLSQYPERHTLVLLHHHSLLVGSAWLDQHTLKD
ADQFWQVVERHANVRAIICGHVHQDMHKTHRGAAVIATPSTCVQFKPNSDDFALDTCSPG
WRELELHADGSFDTRVKRLEEGLFTPNFDSNGY
>A0A2H5VX73|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR10|TrEMBL
MVVRLRFLQFSDVHLDSRLTGSQLAWPREKREQRRQEITELVGKACRLAREHKVEALFIP
GDLWDDEAISAETVARVLEAFASLDPIPVFIAPGNHDCCSPTSFYADEVLRARGMRLWPK
NVTIFRTAEFETVPHPARPEVTITGRAHVRNVPLEERLLGAPIPRPRAPISVLLFHGSWI
EYAGRDRSEKMFTAPFSRQELLAQGFSYAALGHYHHYAEITDAEGRVRAAYTGCLAGRYL
SEAGPHYALLGEIGEHGLLAMEKIRVDERMIHDVEVDVTGVETESGLRERVIGRLRECGA
TASDIVFLRMEGRLPRGLRPASILEDLQHEYFHLAIADRTRPAYDLDTADPRTTQGRFIQ
EMRRRITATSDPQERALLERALDYGLDALIQGEVKPIYEE
>A0A427PST2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. FDAARGOS_515|TrEMBL
MSFQVVPTSAQEYVLIQITDTHLLEQPEHEFVGMNPEQSFHEVMTHIQQHYPQADAIIHT
GDLAQAPRPKTYQRYLHFMQQLGIPFFHTPGNHDDEKYFPFHQENPQQPVLIELGDWRII
LLNTAVSNRVDGLVSTSQLEQLTDLLEQHQAHPTILACHHHPFEMHSKWIDQHKLKNSQA
VFNLLERFKQVKAILYGHVHQNSSNFWQHIECLSTPSTSVQFKPCSEQFALDAVAPGYRV
LKLKTNGTFETVVQRLEHINHLINTEISGY
>A0A1Q9GYA6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium damsela subsp. piscicida|TrEMBL
MLTYSLPPRQSDSVVLLQITDTHLFANDAGSLLGVATKDSFHAVLAAIDHQARPFDAIIA
TGDISQDHSTESYQHFAQGIARWQQPCFWLPGNHDYQPSMKAVLPSPQIKPCEQVLLGEH
WQMILLDSQVPGVPHGELRAEQLDMLDRALAAHSERHALVLLHHHPLAAGSAWLDQHQLH
NADDFWQVLARYPTKVKSVLCGHIHQELDCMRQGVRVLATPSTCIQFLPDSDDFALDSKA
PGWRYLELTPQGDVHTQIHRLANDQFAPDLNSAGY
>A0A4R0DWV8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter terrestris|TrEMBL
MTLSNCHETQQDWTIIQISDTHLMNQEDLEFVHMNPEHSFHAVIRQIQQQYPNVDAIIHT
GDLAQVPVKETYSRYLAFMQRLGIPFYQIPGNHDNIDLFPFYHNQNQAHAIHFGKWSIVL
LNSAVAGKTDGWIEQVQLQQLDQILSKFQQQYVIVACHHHPFDMQSKWIDQHKLKNTENL
TGVLAKHTNVKAVISGHVHQDAWNEWKNIQFFSTPSTCVQFKPLSDDFALDEQAPGFRVL
HLKANGELQTEIYRTEKVQQKINTEISGY
>A0A5E4XPY5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea morbifera|TrEMBL
MSQTSQASQASPASSDAAHLHGKPTKRTLPARPRWLMLAIIALLHAYIGWRLLPPLPVAV
AWKVLGGLWLLASTVLIPLGLMSRAIQKEPLATLLTWTGMTAIGVFSTLFVLTLLRDVVL
GAAMLFSAHDPQLVVRSAVIVLALTAVATILGFYNARRLARVVHIDVPIANLPPELKGFT
IVQLSDIHVSSTIRRSYIEAIVEASNALEPDLVAITGDLVDGGVPALREHIAPLARLTSR
HGTYVCTGNHEYYSGAPAWVEELRRIGLTVLENEHVVLDHEGAWLTVAGVTDFTAHHFDP
EKRSDPLAAVAGAPEDAPRVLLAHQPRSAPAAHEAGFDLQLSGHTHGGQFWPWMYFVPLQ
QPYVHGLHRLGRLAIYVSRGTGYWGPPKRFGAPSEITRLRLVPKVG
>A0A385ZCM2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces griseorubiginosus|TrEMBL
MIRVAAVGDIHMGPESQGVLRPAFDTLSDCADLLLLAGDLTRHGTPEEARVVAQEMRDLP
VPVVAVLGNHDHHDEQPEKVAALLEDAGVRVLEGEGTVVECGGTRVGVAGTKGFGGGFVG
RSAGEFGEPLMKEFVRYSRRCADGLRSALEELGRQDCAARVALTHFSPVADTLAGEPLEI
YPFLGNYLLAEAIDTAGADLSVHGHAHAGSEHGMTAGGVRVRNVAQPVIRRAFNVYHLHE
N
>A0A8B6GII9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mytilus galloprovincialis|TrEMBL
MNRPKSVKRHEKIKAASFDVENGTGPGRPTLEGSSPSSSRLVLQNLPQRRESFLYRSDSD
YDLSPKSVSRHSSMQSEIHADDLIVTPFAQILASLRSVRNNYISLTNVQAPRER
>A0A7C1YRC8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gammaproteobacteria bacterium|TrEMBL
MSYSGKSEKLIPLTTNNPVQARILHLTDTHLHANPDYVMMGRNTRLSLLALLEHIHSESE
KPDIVLVTGDLTHDETSKGYRDLRAILETLKAPVYVLPGNHDIPKLMHRHMNKGQVGTQR
QILIHNWQIVMLDSTIRQSDNGRLDDSQLQFLQHCLGQYPERYTVICLHHPPLPTGSPWL
DTMQLENSTQFLNIIDKQPGVRAVLWGHIHQEFSAQLNNIQLLSTPSTFSQFKPLSSTYA
VDKKRNAGYRWLELSDNGELETRVAWLPG
>A0A6J5D1Q1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia humisilvae|TrEMBL
MLLAQISDLHIKRPGALAYRRVDTAAYFSRCVAALNALVPRPNAVIVTGDLVDQGDVEQY
EHLKALLEPLQIPYYLLVGNHDDRAALRTVFSERQELFAGGEFVQYAFDVGALRVLALDS
IVPGASGGTLCATRLAWLAAQLDAASGKPVIVALHHPPFVSGIGHMDQVRLDPAAAREVE
TLIARHPNVERVICGHVHRPMFVRFGGTIASAVPAPAHQVALDLRDDAPSVFRMEAPAFA
LHWYDAATGLVTHHAYVDQGDGPYPFHEPAGALID
>A0A0A2XS31|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gallibacterium genomosp. 2|TrEMBL
MSDLFRDESAGVIKLLQVTDPHLFADEDGELLGINTFDSFRQVLSEIKKSGFESNYILAT
GDFVQDNSEAGYHRFVKEIVQLGKKIFWIPGNHDFQPKMEAVFDLYKAVIQPEKHLLLGE
SWQVILLDSQLYGVPHGMLSEEELKWLEQRLSLYPDRNTLIVLHHHLLPTNSAWLDQHNL
RNPYDFSEVLAKHQKIKAIVYGHIHQEVNAVWQGIPVFATPSTCIQFKPDCAYFTLDNLQ
PGWREISLYPDGRLETQVHRIKDKVFLPKDNMNGY
>A0A829T4S9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. JCM 18905|TrEMBL
MQSFSDSIKLLQITDTHLFAADEGSLLSVKTADSFNAVVADVLRRNVTFDYILATGGDIS
QDHSAESYQRFAEGIELLEKDCFWLPGNHDYKPIMGSVLPSQQIKAAEHVLLGAHWQLVL
LDSQVVGVPPHGRLSDQQLALLEEKLAEHPERHTLVLLHHHPLLVGSAWLDQHTLKDAEA
FWQVVDRFDNVKGILCGHVHQDMNVLHNGIRVMATPSTCVQFKPNSDDFALDTTSPGWRE
LQLHACGDITTQVGRLPDGQFQPDFSSNGY
>A0A7V8V3F9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bremerella alba|TrEMBL
MSKYSDLSFASERSRRRFLQTGALLIAGAGTAQAQTQGEEPMLRIGLMTDLHYADKKPAG
SRYYRETLAKIAEASGQLAKARLDFLVELGDFIDAADAVDVELRYLKTIAKPFAEICHER
HHVLGNHCVDTLTKEEFLGTVEQEKSYYSFDRGGYHFVVLDACFRSDGKPYGRNNSKWTD
ANIPPDELEWLADDLKQSNKSTIVFAHQRLDYEGNHAVNNSPAVRKIFEESGNVTTVFQG
HSHANDYRQVNGVHYCTLRAMIEDSGLANSGFAILEIDTRGGLKIEGFQKQVSYQWT
>A0A2J8LWN5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pan troglodytes|TrEMBL
MPLVDFFCETCSKPWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISTTFLGSVHGPG
DSRRPLRGCHPRCGSPWGLQPVPHQHQFGAGAHVQR
>A0A831RP65|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sedimenticola thiotaurini|TrEMBL
MSHQAIATAHPLQPLPPGAFRILQITDSHLYADPHGCLAGINTLQSFQAVLEQARALPAE
MILATGDLVHDASPEGYQRVRDAFAALGLPVYCLPGNHDLPAVMSRCLDRDGITSPKLVS
HGDWAIFLLDSTIPGEEGGRLAEEELDRLEQGLEQNPGKHALICLHHHPVPVGSAWMDRM
ALENPERFFGLLQRFPNVRGILWGHIHQTYDATYRDMRLMGSPSTCIQFTPRVDHFAIDN
EPPGMRWLELFPDGRIRTGVQRLQRMPLGLDLSSVGY
>A0A8J6QFX7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Neiella sp. HB171785|TrEMBL
MNNQEFLTLAESETGTLTILQITDTHLFGDPDKDLLGVNTRDSFLAVLASIKSDKQPFDL
VVVTGDISQDDSPASYQAFAEEIAVFGKPVVWLPGNHDDGLIMPDLLGAEPLSCADRVLT
DHWQLLMLNSQVRGFTFGELAQSQLEFVAQSLAEHPDHFTLVFVHHNPVPMGCRWLDQHR
MKNGESLLSALTQADNARGVVWGHVHQDWQQTRDHLHLIATPSTCIQFKPRSEQFALDKR
PPGYRYLSLHRDGSLTTELKRLASDAFVPNLRAQGY
>A0A8C4W527|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gopherus evgoodei|TrEMBL
MTAKDSSRELAAPESDIYIKTFKEQMHLELELPKLPGNRPTSPKISPRSSPRNSPCFFRK
LLVNKSIRQRRRFTVAHTCFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFL
YRSDSDYDLSPKTMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNK
>A0A2H9TCR6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|invertebrate metagenome|TrEMBL
MPIRLIQISDTHLFGDPEKRYHGMDTYASLQSVLKLIVKKHPDMKALLVTGDLTQDEMPA
SYQRLVQVLSPLSVPFYWLCGNHDVKSLMMQVAPSSMITTVDLGSWQVLLLNSQKSGEVA
GEIDSKELTGLCQQLEQTPDVPTVLALHHHIDAIDSVWMDESKVINANALKDVLRQYPQV
KVIIHGHIHQERTSMIEGVPCFAVPSTCVQFAPYEENYTIDDQMPGYRILDLFDDGAFHS
EVVRISTI
>W1IP27|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus cabanillasii JM26|TrEMBL
MESLLEIPVAKGATARILQITDMHLFANKGDSLLGVNTYRSYHAVLDAILEQNLDIDLVV
ATGDLVQDQTTGAYQHFVEGVARLPAPCVWLPGNHDYQPAMVDVLAAAGLPLSKQIFIGQ
HWQLIMLDSQVQGVPHGELTDYQLEWMTKCLDEHSDRYTVVMLHHHPVPSGCTWLDQHCL
RNAPALAEFLKDKPQVKTILCGHIHQELDDMWNGIRVMATPSTCVQFKPHCTNFMLDTMA
PGWRYLELSVTGEGEAKLQTQLHRLKSNEFCPDLDSDGY
>A0A5C4PH16|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. ICMP22404|TrEMBL
MPSVSTLTAADPVLLVQLSDSHLFAEADGSLLGMNTRDSLRAVIDLVLKQQPNIDLMLAT
GDLSQDGTLQSYEAFHQMSARIDAPARWIPGNHDEPQVMLQAAVQSMLLDPVVDIGNWRI
TLLDSAVPGSVPGFLAPEQLILLANALSEAPERHHLVCLHHHPVSIGCEWMAPIGLRNPD
ALFAVLDRFPQVRGVLWGHVHQEVDQVREGVRLLASPSTCIQFEPGSVDFAVGEQAPGYR
WLRLLPDGRLETGVERVVGFEFVVDYGAEGY
>A0A829ZHN2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lactobacillaceae bacterium|TrEMBL
MKFCTSDTHFFHDSLLGTNQFAPRPFKNVNEMNQIIIDNWNDKVGENDIVYHLGDIALYF
TKPQRDAYQAILEILLQLHGHLILIKGNHDNRDLFKYLENNNYEFNGLPKFQFHDVGVLL
KYNHRQYYLTHYPLMLGIAPQIINLHGHIHHYSVPIKENINVGVDAPELDYLEKRPKFGA
PLNFHEIEEIVAQKAMKYPGQK
>A0A0F5ZZD0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Grimontia sp. AD028|TrEMBL
MRISHLPSQHSQTVRLLQITDTHLFADPYGCLLGLNTAASFQAVVGEIQSSQVEFDAIIA
TGDISQDHTAESYQRFVDGIAHWSQPCFWLPGNHDYQQEMQSILTQSTLQRCDSVLVGEH
WQLVVLDSQVKGVPHGRLSKEQLSLLDTALSTNKDRHTLVLLHHHPLPAGSAWLDQHQLH
NQEDFWAVIEKHNNVKGVVCGHIHQALDTEHKGRRVMAAPSTCIQFKPDSDDFALDSTNP
GWREIELHQDGTIITHVGRLKGTEFQPDMNSTGY
>A0A8J7H6Y9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Symbiopectobacterium sp. PLON1|TrEMBL
MESLLKVPVASGARIRILQITDTHLFAGEHETLLGVNTYRSYHAVLSAIQAQGQDVDLIV
ATGDLAQDHSQEAYHHFTRGIAQLSAPCVWLPGNHDFQPAMVDVLAQAGIAPSKHVLLGD
AWQIVLLDSQVFGVPHGELSEYQLEWLECSLLRFPERHTLLLLHHHPLASGCTWLDQHSL
RNSHHLDAVLARYPQVKNVLCGHIHQELDLDWNGRRLMATPSTCVQFKPHCTNFTIDDVG
PGWRYLDLLSDGSLETRVYRLSGSEFLPDMDSDGY
>A0A1X3RWL8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lonsdalea iberica|TrEMBL
MESQLTLPVARGARIRILQITDTHLFAGKQETLLGVDTYHSYHAVLEAIAAQPHDFDLIA
ATGDLAQDQSLAAYQHFAEGIRRFDVPCVWLPGNHDFQPAMVDALALAGIAPSKHVLLGD
HWQVILLDSQVFGVPHGELSDYQLEWLERILSSHPERFTLLMLHHHPLPSGCTWLDQHSL
RNAHSLDDVLSRYPNVNTVLCGHIHQELDLDWHGRRLLATPSTCVQFRPHCTNFTIDNVA
PGWRYLELLPEGGVETQVVRLEGNAFLPDMDSDGY
>A0A482XE53|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Laodelphax striatellus|TrEMBL
MGCAPSTHKKRRPRDDHLIETSGGNDRDRSCRGKRDSEAIIYSPTVRDELQEGGDGATCA
SVWDWCWTNTCCKHGRANGMHRYPLVRTNLKAQDQTTDSASDGEQLRPRASLTQHPMKVL
LVFYKDDATCRSLAGAADRLGYSREVITSRDLAVDVYQAHAFLPHVIIVDMRYPNFHGEL
LCRALKSDKKKSPDVLFVAILNKKAVKSEKDLKSVLSYGFDRVLVEPFTQLQSVSQLLQL
CSDEIDRLALHSHNSLLTLSLERSRDLILITDQHHTIQYVNKTWCSIIGYRAEDVISRHV
QSLHHVGNMDAVLRQVERGHEWDGKVGWKSKHGENILLQCHAAPFCLMGKEPTNFVYVQE
NPQDAHGFPRGSINSLRKGSFDLKSITSDGSASARRQSLAKLHNLPMEAPITKVITLICA
AQESSTGPVIQLLDKVLDILRTTELYSTHLKNNDNLKCDDPVTSDLIGALITQPGPLPIS
SVRRSSDSSNLKQSMVNQSGKVAFYSLTQSIKDVLDNSLNWEFDIFKLEEVTGRRPLAYL
GMNLLTHYNVNKTLGVDERTLFNWLSVIEQHYHIDNSYHNSTHAADVMQATSVFLDRDRI
KRSLDDLDEACCLIAAACHDIDHPGKSSAFLCNAGNDLAILYNDISVLESHHAALTFKLT
LKDERVNIFRGLERDTYKVVRQNVVDMILATEMTKHFEHISKFVSVFNKPSVAIEDGSQT
EIKVGLLELIKRMMIKCADVSNPTRPLHSCVEWARRIAEEYFNQTDEEKARRLPVVMPMF
DRTTCSIPKSQMGFFDFIVNDMFEAWDVFVDMPELLYHLRHNYQFWKDMEERGQTTLDKL
PTLGSKGNLPNIPENTSSSYSNSEH
>A0A1G4QMF9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas peli|TrEMBL
MPGAPIQTTAVDRSVLLVQLSDSHLFADGAGKLLGMDTQDSLQRVIERVLQEQPQIDLVL
ASGDLSQDGSAESYQRFREMTAAITAPARWFPGNHDEVPAMQAACVGSDLLEPVIDLGNW
RVTLLDSSIPGAVPGYLSDQQLALLERALSEAPDRHHLICLHHHPVSIGCKWMEPIGLRN
PDALFAVLERFSQVRAVLWGHIHQELDQQRGTIRLLASPSTCVQFAPGSEEFQVDKTAPG
YRWLRLFDDGRLETGVSRVTGIKFEIDYTIKGY
>A0A853RI36|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus FF-500|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIKPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPKRNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAVLCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTQVRRLPNGQFSPDFDAGGY
>A0A857JKY0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraglaciecola mesophila|TrEMBL
MKVSLISCSIRTLLFISLWLITTAASGESAPDKALTPHPAASDWPDRIIATPTAFPANSF
SLTWRTDQSVKKSYGQIVQASPDARYDINAIQIAAQTYTMSLAQGTTQQGQFSYPKNEGL
QSVSYHSLTFKDLKPDTYYNYRVAGATGKWSPWQQIKTAAAKTDQDFSFLYFGDAQNGIY
SHWPLMLRRAWQHAQDAQFAIYAGDLVNEGASDQQWSNWLNAGQFVHRTLPAVLVAGNHE
YDWQVHENAEKSWALSTLWQNQFTLPRTPSLPNALQETAYVTHYPDMDVFVLDSEARGDI
NLLQAQAKWLDQALQTSTAKWRIVTMHHPIFSSCGMPLNTPGQDEPEIRSAFLPIMLKHK
VDLVLQGHDHAYARGSIGAEKDLEKVATSKISKQVKSVFITSVAGPKTYPIKPTRWDEYK
NYGVKLERIGENTPTYQVINKTADTLKYQSFTANGEIYDAFTISKDRDGRKILNVAKDLP
PERTFDNTGVYKSHHDLAE
>A0A0A3ZA38|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia typographi|TrEMBL
MDSLLKLPAASGSRVRILQITDTHLFAGKDETLLGVNTWASFDAVLQAISASPRHYDLIV
ATGDLAQDHTVEAYQHFAEGIARLPAPCVWLPGNHDFQPAMFSTLAESKIADEKHVLIGD
SWQIVLLDSQVFGVPHGMLSDYQLEWLEKTLAIEPRRHTLVLLHHHPLPSGCTWLDQHSL
RNSHMLEAVLQNFPLATTLICGHIHQDLDLNWNGRRLLATPSTCVQFKPHCTSFTIDSEA
PGWRWLDLLPDGRVETQVERLNTRAFSPDPDSEGY
>A0A6I1YSE0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces sp. RB17|TrEMBL
MTAYDDHQGPAPAGGAEEPATEHGMTRRQLLRHAGWFGGAVVLTVAGGEVISHVAGTRDA
AAAAAGAAGSPNGALRFVQVSDSHIGFQGPANTDVVGSFTEAVHQVNGLGFRPDFVMHSG
DLTHLSTAGQFDQVRQMLAGLRTDRVFTVPGEHDSIGDAGRAYRQAFGKGTLGDGWYSFD
THGVHFVALVNTLRLEKLGHLGTEQIDFVRKDLSGLPSDTPVVVFSHIPLFAMYPKWGWS
TDDALKVIALLRRFSSVTCLNGHVHQLFTKTEGNITFHSATTTAYPLPKPGRAPAPTPQV
VPARQLKDALGIRTVGYRRGDQQLAIKDERLA
>A0A447QK36|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia rubidaea|TrEMBL
MESLFKLPVASGAKVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAVRAQQREFDLVV
ATGDLAQDHTPEAYRHFADGISQLPAPCVWLPGNHDFQPAMVDALAAAGITPSKHVLLGE
HWQVILLDSQVFGVPHGELSEYQLEWMERCLQAYPDRYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAVLLRYPKVNTLLCGHIHQELDLGWQGRRLLASPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVCRLDNDDFRPDMDSDGY
>A0A4Q5VMK3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moraxellaceae bacterium|TrEMBL
MIYQVEIPASVLSQERPLRLVQCSDMHLFADPATKLLGLNTQQSFQNVVELIQQQQPHID
LLLTTGDIAQQSAPETYQRFLKTIQPLTTEPIRAPHFCIPGNHDLDDSYVDGLNMNPLPC
EVIIGNWCCILLNSTVDHEIAGSFSNSTLEYLQQALERQRNRHVLIALHHNPIAVGCEWL
DQHMLKTSQTFFDILQPFSNVKLVLHGHVHQIFEQVYQQVHYLSCPSTSLQFKPKHDKFT
LDTANPGYRWLDLYANGHFETDVCRLEKFNFSIDYQSNGY
>A0A8H9NA43|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio parahaemolyticus|TrEMBL
MQSSNDSIKLLQITDTHLFAADEGSLLSVKTADSFSAVVNEVLRRKVGFDYILATGDISQ
DHSAESYQRFADGIAPLQKDCYWLPGNHDYKPNMGSVLPSPQIQSAEHVLLGENWQLILL
DSQVVGVPHGRLSDQQLTLLEEKLTEFPERHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFDNVKGILCGHVHQDMNVIHKGIRVMATPSTCVQFKPNSDDFALDTTSPGWRELE
LHTNGDITTHVDRLPEGQFQPDFSSNGY
>A0A5J0XQ20|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Agama|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDVDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETKVHRLQDTRFRPDTASEGY
>A0A855J8Z9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIEPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVKQHTNVKAILCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTQVRRLPNGQFSPDFDAGGY
>A0A7Y4G057|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio splendidus|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIKPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQIDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWDVVQQHTNVKAVLCGHVHQDMNRNHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTQVRRLPNGQFSPDFDAGGY
>A0A7Y4LQF9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio coralliilyticus|TrEMBL
MKVTSCSSDGSIRLLQITDTHLFEATDGSLLSVNTADSFNAVVDAIVEENPVYDAVLATG
DISQDHSEVSYQRFEQGIVPLKKKCFWLPGNHDFKPSMNSVIPSQQIQQIDHVLLGDTWQ
MIMLDSQVVGVPHGRLSDKQLNLLEEKLSQYPERYTLILLHHHPLLVGSAWLDQHTLKDS
DDFWQVVDQHNNVKAVLCGHVHQDMNVMRNAVRVMATPSTCVQFKPNSDDFALDYQSPGW
RELLLRDNGEVETQVKRLPAGCFQPDFNSAGY
>A0A2J7VDI1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Variovorax sp. B4|TrEMBL
MLLLPFIGYRRRCPSEIKSASRKVGGDMKLLALSDLHLEFGTFRVPKFEADVVILAGDIA
ATAAKALRWAQRPDNFGEQTPIVFVPGNHEFYGGVMDTTLEDMDRAASGNVHALNSGEVV
LQGVRFLGTTLWTDFALAIKTGEGTMSDVPRAMEAARSSMNDYRRIRVVEAVSRRGATKR
EKRRLAPEDTAALHLRQRQWLADRLVEPFDGPTVVVTHHAPHRGSLHPRFASNWVSTAYV
NELPESFFKVAACWIHGHTHESMDYRVGNTRVVCNPRGYASSFEPELNPAFNPALIIEI
>A0A2R9C8H2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pan paniscus|TrEMBL
IFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSS
IASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITGK
KDLELILHVSRKKPFLPRVYITPTPISCCNLKMLKKFFLLYIIISIIDLTNCLSCYLEHF
C
>A0A4U1YPJ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio genomosp. F6|TrEMBL
MKLSSSSESALGSIKLLQITDTHLFAPADGSLLSVNTFDSFQAVVRDIQAKAFKFDAILA
TGDISQDHSQESYQKFESGIECLQKPCFWLPGNHDYKPNMSSVLPSPQIQCVEHVLLGER
WQMIMLDSQVVGVPHGRLSDQQLALLDEQLTLHSDRHTLVLLHHHPILVGSEWLDQHTLK
DAEQFWNVVDQHQNVRGVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSNDFALDSQSP
GWRELELHLDGSIETQVNRLSDGRFLPDFNSDGY
>A0A2R9CIW4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pan paniscus|TrEMBL
AFQGSRSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKS
MSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINK
ATITG
>A0A3Q7P1U1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Callorhinus ursinus|TrEMBL
MKKSRSVMAVAADDNVKDYLECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQS
ERARTPEGDGISRPTTLPLRTLPSIAITTVSQECFDVENGPCPGRSPLDPQASSSSGLVL
HATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVR
NNFTLLTNLHGASNKRSPAAATQPSVSRVNLQGKLPCEAWLHVSK
>A0A221US87|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arenibacter algicola|TrEMBL
MRKHYLLIIILFLLVGCATYKTKYVESSTVGNISGDSELLHTFYFIGDAGKSPMNDQSEA
LKAFQKALGKAGKNSTALFLGDNIYPAGMPNKKDSTQAYLEAKNNLDAQLETLSQFKGNP
IFIPGNHDWYNESLEGLERQQKYIQKKLDSKEVFFPEDGCPIEKIDINDKIVLIAIDSEW
YLTNWDKHPKMNDKCEIKDRETFFEELESLIKKNRDRTTILAIHHPMFSYGPHGGQYSAK
LHLNPAGGKFPFPVLGSFVNLIRKTSGASYADLQNKRYTELRNRLVTLAQYSQKVILTSG
HEHTLQYIVEDNTPQIVSGSGAKEGATRLLNGSKFSTGRMGFAELKVFNDGSSEVRYFGV
GENNDPDLLFSTQVLPPDRNENYIFNGNNFPREVKASVYPKEDIEKSKFFKTIWGERYRK
YYAMEVNAPTLRLDTLFGGLKPVRKGGGNQSKSLRLSDKNGKEYVIRAVKKSAEVYLQAM
AFKDKYVLGEFKDTYTEKLLMDFYTGALPYGLLTVGTLSDAIDLYHTNPKLYYIPKQSAL
AEFNGEFGDELYILEEQVGDGHGELGSFGYADKIESTWDMIDKIKRDEKYVVNTDRYLRT
RLFDMVMGDWDRHDDQWRWGEVKDKETGKIVFEAIPRDRDQVYSIWGDGALMGVATRIIP
ALQMMEGFNNDIRNVEAFNKSAYGLDVTLLAETTKADWEKEVQYIQQNLTPAVIDEAFKA
FPQEILDENILNLKSILLSRINNLPKIAEDYFLALNQYVVIKGTDKDDWFEINNLAEQEV
EIKAYRKIDGKKEKLFFQKKFNHNITKEIWIYGLDDDDIFEVEGGKGNKIKIRLIGGQNN
DVYDISEGSNTWIYDHRSKKNTFKEIKGAKLRLTNDYETNTYQPLKLRTSTRQIIPTIGF
NPDDGMKLGFNASNTFYGLRQNPYTTQHSYNAAYYFATNGFELGYKGEFAHILENWNLEL
AARFTSPNFSVNFFGIGNETENFDDTLEMDYNRVKIQNLSFSPSLIWRGQLGAKFRTGIS
LESLEVEETEDRFVNTFYLANGEENRNSFIGVDAEYTYENLDNAAFPTMGMTTGLLLGYK
ASLENQGQAYAYIVPSLSLDHKLVSNGRLVLASKWKAHFNLGDDYEFYQAASIGGIDGLR
GFRNQRFSGKSSYYQNTDLRYSLKSLKTGLLPVTVGVYGGFDYGRVWTPNENSDLWHTSY
GGGFFLNGADVMTARVALFNSVDGPRFSFGIGFGF
>A0A7U9N3M3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lachnospiraceae bacterium|TrEMBL
MLRTFLQNIRNTILKRQNEVVHFKFELGTSFHPETGFFEKEHPECMADFRFYQVSRGDRV
ICRNSAYRYGIASFGAEIEERLIYTYCYQEEENWSAYLGDFEPDCLKSGNSAVLQDGWIR
IAVKRVDGAALTCEDINAVTEGMALIRRRQTYKEKDYFKQEIEQTIQAVNEKREQDSLVF
GLMADSHYVINGGWEDSIANLQAVNRKAPFDAMIHLGDLTDGMVPLAITREYAVKVMEDL
HSLKVPVYLTLGNHDSNYFRSNPEWLNEKEQSFLYLGKEEPWYYVDFEKQKLRCLFLHSF
NHREKIRYGFSMEEVEWVKQVLAQTPDAYRVLVFAHVPLLPEMHFWTKEIRNSKEMLEAL
EEYVQQGGKILAYIHGHNHADQIYYGKRFPIVSIGCAKCEDFKDKKPEGAVTYDRKMKTL
TQELWDVMIVNGKKDEIEFIRFGAGEDRRILC
>A0A7U3Z5T5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia sp. AS13|TrEMBL
MESLFKLTVASGARVRILQITDTHLFAGENETLLGINTYRSYHAVLDAIMAQQRDVDLVV
ATGDLAQDHSLAAYRHFAEGIARLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLLGE
NWQVLLLDSQVFGVPHGELSDYQLEWMERCLQAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAVLLRYPNVNTVVCGHIHQDLDLEWQGRRLLASPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSEGY
>A0A498MML0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Labeo rohita|TrEMBL
MSLPARTDLLSLELLAKPRCMYTTGSPFATNKPIDIKARRRCFDVDNGTSSGRSPLDPMT
SPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDMNNHLPRPGLVSRRS
EPVISGNHGDDLIVTPFAQVLASLRTVRNNFAALTNLQQDRTSNKRSPMCNQPPLTKASF
TGAWGSGALYARSPARLD
>A0A812DZU1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sepia pharaonis|TrEMBL
MFAALCTYMNPGNALHLWNTHKESIIEDFFHQGFSSYIYFLDVYCFFPSFLPSFFNSNIF
FLSFFFLLFVFFHSFFHSFFILFFIYLFIYFILSFFYSFFFLSSFLLILFSIFLISLFHS
FFHNIFLLFLLPFFDCFFLFFFHSFFRCLFLLFLLSFIHSFIFSLFLSFILSSIHSFFYS
FFLSFFLFVRFFSFSLIFSLSLFIYFFSFSFSLFLSLSCRFYFFLFQPNSFFLIFLWSFL
FPPFLIHYFFSSLWFIRSFIFLSLLSSPLLPHSLSQRLPFFLSVFLSFFFFFFLFWEIFV
LSSSSFYFLFIFHSSFIINSFFLSFFLSFFLFLSLLYASFLFSFHILFILLLIHFSFIIT
LFLSLAIYVFSLTSIYSFTHSSVHHFFLSFFLSFFFCLSFFLFSGSLSFSSFLNASLIPL
FLFIYSSNPSFITN
>D0I8A4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Grimontia hollisae CIP 101886|TrEMBL
MRISHQPSQYSQTVRLLQITDTHLFADPYGSLLGVKTAASFQAVVENIQSLGVEFDAMIA
TGDISQDHTAESYQRFVDGISHWTQPCFWLPGNHDFQPEMQAVLAQSPLQRSDVVLMGEH
WQLVILDSQVKGVPHGRLSEAQLALLDLALVTHSERYTLVLLHHHPLPAGSAWLDQHQLH
NRDEFWTVVDRHTNVKGVVCGHIHQALDTHYKGCRVMAAPSTCIQFKPDSDDFALDTTNP
GWREIELHHDGTISSYVGRLKGTDFQPDMNSSGY
>N6WM68|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter nanhaiticus D15-8W|TrEMBL
MPSPVSPENIATRAPSLRILQLTDPHLMADPEGTLLGMNTRESLDAVIALAKREPHAPDL
VIASGDIAQDSSETAYRVFQEKMSVYSCPVIWFPGNHDDVEVMHEVIAGTNAEQRRLLVG
GWQLIFLNSAVPGKVYGALSSGELSFLNDCLAEHPERPTLIAFHHHPVDVNCTWMSQIGL
TNSDALMAVLEGQSQVRALLWGHIHQTWDGELNGMRLMATPSTCIQFAPGSNEFSIDGQA
PGYRWIDLYPDGTLDTHVRRAEDYVFTVDLDSQGY
>A0A5S4U3X2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dickeya sp. ws52|TrEMBL
MESLLTLPVARGARIRILQITDTHLFAAEQGTLLGVNTYRSYQAVLAAIAAQQLDVDLIT
ATGDLAQDHTQDAYTHFAHGIRRFNAPCVWLPGNHDFQPAMVDVLARSGIVPSKHVLLGD
HWQVILLDSQVFGVPHGELSEYQLEWLERSLLSQPARHTLLMLHHHPLPSGCTWLDQHSL
RNAHSLDALLARFPQVRTVLCGHIHQEMDLDWNGRRLLATPSTCVQFKPHCTNFTIDNVA
PGWRYLELLPDGEVETQVCRLDGNEFLPDMDSDGY
>A0A1U7CYS1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paludisphaera borealis|TrEMBL
MVANLLIYLIVAIGEAVCVAFAINVVHGRAWKVRWHEKATMAFMAVCGLGSLELARRYRL
TPFADWPVLLKSLATLCSFVALVVLPAVTFARSRRRTPEGMVRDDHRSVLDGKNREAFIG
QGTFSWMLRLPGNESLDLTVHEWSLRIPQLPPELDELSILHLTDLHFSHAYDRRYFEAVV
EAAASAPADLVFVTGDLVDEPECIEWITPLLARLSGPLGRFAILGNHDHHHDMDRIARAT
TAAGYTVLDGDVATVDVHGRRLAIGGTCAPWGPAIAAGSIPEADFSMLLSHTPDLAYKAA
AQGWDFMLCGHNHGGQIRLPVIGPVLMPSRFSRRFDRGFFRIDPTLMYVSQGVGAKHPIR
YGCPPEISRFTLVRHDVAAPRDQSAGAARQPVEA
>A0A071LYB7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mangrovibacter sp. MFB070|TrEMBL
MESLLTIPAADEASIRILQITDTHLFAGKDETLLGVNTWSSYRAVLAAIHKEARPCDLIV
ATGDLAQDQSNEAYQHFAEGVSSLAAPCVWLPGNHDFQPAMFSSLKESGISSSKQVLAGK
SWQIVLLDSQVFGVPHGELSEYQLEWLEKKLAENPDRQTLLLLHHHPLPAGCSWLDQHSL
RNAQALDDVLQRYAGVKHLLCGHIHQEMDVDWNGRRMMATPSTCVQFKPHCANFTLDTIA
PGWRWITLHPDGSLTTEVCRLSGSAFSPDTDSEGY
>A0A1V3JK20|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rodentibacter genomosp. 2|TrEMBL
MKNTFTYQPQKTTIKLLQITDPHLFKDEQTELLGVNTQASLTQVLKEIQQEDIDFDAIIA
TGDLVQDSSGEGYQRFVKMMKPLAKPVFWIPGNHDFQPKMVEHLNQEPLETEKHILLGKH
WQALLLDSQVYGVPHGELSQYQLDLLKAILEKYPERYALIVLHHHLLPTNSAWLDQHNLR
NSHDLLDVLAPFKNVKAILYGHIHQQVDSWWQGYQVMATPSTCIQFKADSQYFALDEVQP
GWREIELYPDGSIATQVKRIQQAMFLPNIHENGY
>A0A812F967|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. B1REV9|TrEMBL
MQSSSDSIKLLQITDTHLFAADEGSLLSVRTADSFYAVVQEILKRQVQFEYILATGDISQ
DHSAESYQRFADGIAPLEKDCFWLPGNHDYKPNMGSVLPSSQIQTVEHLYLGEHWQVILL
DSQVVGVPHGRLSDQQLSLLEEKLAENTNRHTLVLLHHHPLLVGSAWLDQHTLKDADAFW
QVVDRFDNVKGIVCGHVHQDMNVVHHGIRVMATPSTCVQFKPNSDDFGLDTLSPGWREIE
LHQSGDITTQVNRLGEGQFQPDFTSNGY
>A0A060YY11|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oncorhynchus mykiss|TrEMBL
MSENRMLRTVNYFLIFSLPLYLPHSFDVENGLSVGRSPLDPQASPGSGLVLQANYAHSQR
RESFLYRSDSDFDLSPKAPSRNSSTASELHGEDMIVTPFAQVLASLRTVRSNFAVLTHQQ
DRQPSKYVQSTPLIPKLACPPNPLTMKYKVDIDMH
>A0A845N8P5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alcanivorax sp. ZXX171|TrEMBL
MTQPVQPLRVVQLSDFHLFADPEGRLLGLNTQFSLEKVLERVREEQAAPDLVVATGDLSQ
DGSFESYQRLERTLADLPAPIYWLEGNHDKPAPMMHALKTHEQRISPCVAELGPWTLVLL
DSTIPGEVPGDLFEEDLAFLDRALDEARGEHLLVCLHHHPVPMNSRWLDTQLVGSAERFF
QVIDAHPRVRGILWGHVHQEYDAERNGVRLLAVPSTCVQFKPGSEDFAVDDANPGYRWLD
LYPDGRIDTAVSRVEGIDFKVDFSVKGY
>A0A3G4V9Q9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio mediterranei|TrEMBL
MKTTPSDESQLSSVRLLQLTDTHLFAPQDGCLLSVNTQESFNAVVAEIVAQGTQFDALLA
TGDISQDHTEASYEKFVAGIEPLALPCYWLPGNHDYKPCMNSVVNSPLIQDVTHVLLGEK
WQVVLLDSQVVGVPHGRLSDSQLEFLDRMLSTHCDRHTLVLLHHHPLLVNSAWLDQHSLK
DADEFWNVVEKHDNVRAVLCGHIHQELDEMHGGVRVLATPSTCVQFKPNSNEFALDVRSP
GWRELELREDGCLRTEVKRLANGSFRPDFNAEGY
>A0A679JFV8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hyphomicrobium sp. ghe19|TrEMBL
MLPIVDPRQGDVEDDASSTKRRTLISLAGSLLAEISLPKLVAAWVILIVLPALLLGAGPL
LASIWISSVSSKAAEIYTGLLAPILLAILIVIGWFGGKPLWRLIEANFWSLNALAVQPAY
ALSREALRQLAERFLPANVDQRSRDIARAVSAAVAGLLICAASLWIIALAWPGTRWIGSL
ADLSSPSNLAHIALHNSVVIVAAYLAVAGLVWGLADTIMPQPRDLPRYPPTPATGRIWRV
AHLSDIHVVGERFGFRIEGGRSGPRGNERLKQTLEKLDAEHRERPLDIILITGDITDAGR
SPEWAEFIDALSPYPHLAALTVILPGNHDLNVVDRANPARLDLPTSPKRRLREMRALSTM
ASLQGNRVHVVDDATGKLGATLEEFLEPHAEKIAEFSDRGTVRLSWGLAGLWPEAFPMVL
PPENDDGIGVILLDSTAETHFSFTNALGLVTQEQTRAIEKVTAQFPNARWILALHHHMVE
YPTAAKAMSERIGTALVNGTWFVRRLQRLSGKAIIMHGHRHIDWIGLCGGLVIVSAPSPV
MDVTNDRDTYFYLHNLCIGADGNLALLEPERIDLKADNDLTVAAPTPN
>A0A1A7NQZ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gallibacterium genomosp. 3|TrEMBL
MSDLFQDESAGVIRLLQVTDPHLFADAESELLGINTFASFQQVLSEIKSSGFESDFILAT
GDFVQDGSEDGYHRFVKEIAQLGKKVFWIPGNHDFQPKMEAVFDVYKAIIQPHKHLLLGE
HWQVLLLDSQLYGVPHGMLSEAELAWLEHHLLMYSERNTLVVLHHHLVPTRSAWLDQHNL
RNPYDFSEVLAKHKKVKGILYGHIHQEVNAQWQGIPVFATPSTCIQFKPDCAHFTLDSLQ
PGWREITLHPDGRIETKVQRIKEKVFLPKDNMSGY
>A0A7Y1B509|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. WS 5027|TrEMBL
MPSVSTVNPDAPALLVQLSDSHLFAEADGTLLGMNTRDSLQRVIELARARQPQIDLLLAT
GDLSQDGTLESYQLFRDLSQQIGAPARWIPGNHDEPQVMAQATMGSALLEQVVDVGNWRV
ILLDSAVPGSVPGYLADVQLQLLAQALSEAPGRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEEAPGYR
WLRLHPDGLLETGVERVEGFTFTVDYGSNGY
>A0A828U0U5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli DEC2D|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGSLTTEVHRLADARFQPDTASEGY
>A0A837FHL2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter hormaechei subsp. xiangfangensis|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEKRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGD
QWQILLLDSQVFGVPHGELSDYQLDWLETKLAAEPNRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDGVLAKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLAGAQFRPDTASEGY
>A0A1X3LDW3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli TA054|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A5E4X5T2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pandoraea soli|TrEMBL
MRLHILSDLHLSVAPLAIPEVGADVTILAGDIGRPAQAIDWAKALGRPVIYVPGNHEFYG
ATLAGTLAELRRLCVGTNVHLLERGSVVIGGVRFVGTTLWTDFALYDADGKHDEAVEESR
KFVRDFTRIRVGDPAVPWAELPFFSPDDCAALCRENVAWLGRVLAAPHDGPTVVVTHHAP
TPQSIHPRFAESLVNPAFISDLTSFVDASEAALWIHGHTHDSFDYRVGPTRVLCNPRGYC
FEGRVENAAFDPTLTVRV
>A0A4P6ZCY4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chryseobacterium salivictor|TrEMBL
MNLQTIEKTVQKETLIFTNQRALFWTENKALIISDLHLGKTAYFRKNGIPVPSDILEDDL
ERLDFLIQHFEAEQLIVVGDFLHAGKNADFKIFEEWRKLNITLKIILIKGNHDIKNADFL
LDLNIHIIENSLYTEPFTFIHIPENTENQFSISGHLHPGVTVKLEKRKSVRLPCFRLSEN
QLILPAFSKFTGLDTQSCQDFECIAFTEDLIFEL
>A0A831YYS5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Crenotrichaceae bacterium|TrEMBL
MQSEKNKILRIAQITDSHLFADSSQKLNGLDTLNSLQQVMQAVLDSQPELIIFSGDLVDR
PEAAAYFAVKSVLDLSTVPVFCLPGNHDDPDLLKETLSSEKIHNDFSTLVNNWQLLFLNS
YQPNTHAGKLGDNQLQMLDKHLRKHSEYSALICLHHPPVPIHSSWMDAMGLEQSEELFAV
VDRHPQVKAVIWGHIHQQFNQTRNGVKLLGTPSTCVQFMPGASQFCLDNKPPGYRWLELY
ENGAITTEVIYLPDFDCPGNGLA
>A0A285K261|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sp. CC120223-11|TrEMBL
MESLLNLTLAGGAGVRVLQITDTHLFAEKHETLLGVNTWESYQAVLAAIHASKRECDLVV
ATGDLAQDHSSAAYQHFAEGIAGFDAPCVWLPGNHDFQPAMYSALHDAGISPAKRVFAGE
NWQILMLDSQVFGVPHGELSEFQLEWLEQRLLESPERYTLLLLHHHPLPAGCSWLDQHSL
RNSGALDGVLMRFPRVRHLLCGHIHQEMDVDWNGRRMMATPSTCVQFKPHSANFTLDTIA
PGWRWLELHADGTLTTEVCRLDGTQFRPDTASEGY
>A0A1E4X509|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sp. ANP5|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQANEHPYEVILAT
GDLSQDHSPESYQRFASMMAPLGRPIYWLPGNHDDSPLMTEYLHAAGISESKQLVGEHWQ
VILLDTQVRGKPHGMIGDHQLAALDRALRQYPDRHALITLHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRVASEVWRLPVGQFVPDPNATGY
>A0A8B9V1N0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anas zonorhyncha|TrEMBL
MGGGSRAPGAQHHGEFPRYRRFWGTGGGHPSPPPPIHIPVSPQRCRDATEAAPSGPGPGP
VSGAVRRRFSGTPLLPPLGCRGAEPEPPRVVFTIEESGPSSGDEAEPPRFDLENGLPGRG
ALDPQASPGAGLVLQGTFSHGQRRESFLYRSDSDYDLSPKAMSRNSSIASDLHGEDMIVT
PFAQVLASLRTIRSNFAVLMHLQDRAGTKRASSSSLPSASKASLSAAPAARPPLVRWRWR
WKGCA
>A0A5V7QUD3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Kottbus|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLLDTRFRPDTASEGY
>A0A2J8I2N0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio diazotrophicus|TrEMBL
MNVSPSIDNPDSIKLVQITDTHLFAPDDGCLLSVNTADSFRAVVKEICSQQVQYDAVLAT
GDISQDHSAESYQRFSDSIQMLEKDCFWLPGNHDYKPNMGAVLPSTQIRTEEHVLLGEHW
QMILLDSQVVGVPHGRLSDHQLALLDDKLTQYPDRYTLVLLHHHPLLVGSAWLDQHTLKD
CESFWEVVQRHSNVKAVLCGHVHQNMDKEHMGVRVMATPSTCIQFKPNSNDFALDKTSPG
WRELELCSDGTVKSAVKRLANGVFQPDFDASGY
>A0A0U1I990|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia mollaretii|TrEMBL
MESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGIARLPVPCLWLPGNHDFQPAMVDALADAGIAPSKQVLVGD
NWQILLLDSQVFGVPYGELSDYQLEWMERCLVAHPQRYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGRLETEVRRLASDEFCPDMDADGY
>A0A8J6ZN51|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Fortiea sp. LEGE XX443|TrEMBL
MNPISPVLIAQVTDIHLFAAENHQLLGIPTTESFKVVMERLKELKSEIDLLLLTGDLSGD
GTSQSYDNLQSLVNQLQIPTYWLAGNHDCAIAMNEILNIGMISRRKSFQRGNWNFILLNS
TVTGCVHGHLAPNTLNWLDSELAKLGNNPTLIALHHPPVSVNSAWLDSSSLENSKEFLAV
LDRHPQVKLVLFGHIHQQFQRQRGNVGYLGTPSTCIQFRSNSPTFSIDQKTPGFRLLKLY
PSGIWETSVERVPYFHPLELAAMGY
>A0A351NMR5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacteriaceae bacterium|TrEMBL
MESLLNLNLAGEASIRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAEQRHCDLIV
ATGDLAQDHSAAAYQHFAEGIASFDVPCVWLPGNHDFQPAMYSALQEAGISGAKRVFAGE
SWQILLLDSQVFGVPHGELSEFQLEWLEKKLAEVPERYTLLLLHHHPLPAGCSWLDQHSL
RNSQELDNVLVRYPRVRHLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELNADGTLHTEVSRLQSSRFSPDTASEGY
>A0A1B9QXA7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio genomosp. F10|TrEMBL
MKLLQITDTHLFAPADGDLLSVNTLDSFQAVVSMIQDSGVNFDSILATGDISQDHSVESY
QRFAEGIAPLKQPCYWLPGNHDYQPNMGTVFPSPQIQHIEHLYIGEHWQVIMLDSQVVGM
PHGRLSDRQLDLLDEKLSANPNRHTLVLLHHHPILVGSAWLDQHTLKDSELLWQVLDRHS
NVKAILCGHVHQDMDREFNGVRVMATPSTCIQFKPNSDEFALDKRAPGWRELDLYDDGQL
VTQVQRLPNDRFFPDFTAGGY
>A0A2H5XBA1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR17|TrEMBL
MMRRESLWLTVAIALFALAWLQGIVYVSGQTNEPFAFLALGDIHFDRLEHHDLDYVRQKH
GEGDVRQIQNYSRLTETVLPKTFAEAREHVQTFKPPIAFVAQLGDFVEGLCGTPQLARRH
VEDAIEFVKRAQLGVPFFITKGNHDITGPGAVEAYNQIILPFLGEQLGKTLLSASFTVRR
GNTLFAFFDAYDDASLDWLERTLTEQQAQRVFVLLHPPVVPIGARSLWHLYARPEQQPQR
QRLLNLLGRYHAIVLTAHLHKFGVVVRKTESGSFVQVTLNSVIPSPEVEPKQVLQGVKHY
GPDLVKLEPNFEPQTEAQRREALVAERPFIAYYEYADAPGYAVFVVDASSVHAHFYVGLG
KRRWRSVNLTALLQGQ
>A0A5F5PJN3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Equus caballus|TrEMBL
AFQGSRSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKS
MSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINK
ATITG
>A0A2P7ZWD4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces sp. 111WW2|TrEMBL
MARVPAAVPHALAEVMNPIRNAPRILTRRYRDRRARRGRPAAATPELAARSHPWTRAAGL
VAVVLLGAWLGLLVVGNVRAPVGPMNTTMTLRPSLAGGTKINVSPLGALQLDSHVAPVRL
DVNVDQLDPARAQALVDHPERLSGLQDEVAQDVEHGTLDLAVRSCVAVVTGATALGLVVY
RRPRRALAAGGLALTLLVASGGTAYATWNPDSVLEPKFSGLLSSAPSLVGNARSIVTEFD
VYQKELARLVTNVTKLYDVTSTLPAYQPDPTTIRVLHVSDIHLNPASWKIIGSLVEQYKV
NVIVDSGDTMDHGTAAENGFLDPVEDLGAPYVWVRGNHDSRGTQEYLKHLKNVHVLDDGH
ARTVAGLRFAGMGDPQYTPDRSKADGAEASQELAGARLASALRDQSAAGTPVDIAVAHEP
SAAREVDGDVPLVLAGHIHHEDMEVMKYGTRLRVEGSTGGSGLRAVEGKYPDPIQASILY
FDRDSRRLQAWDEIKLGGLGLTTAEVSRHLPKENQPGATPSPSAGSPSPSGTGPSPSGTR
ASPTAPGSPAPSTP
>A0A3Q4HWZ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Neolamprologus brichardi|TrEMBL
AHHPDRCSYIMGKECRLYSKLLGGQKGHFLIVNGPSSSCSPLDPQASPGSGLVLHTNFPG
HNQRRESFLYRSDSDYELSPKSMSRNSSIASELHGDDLIVTPFAQVNIPLSTRPVGGAAG
QRSGSMCSVCSDCVSLCAGCLLTDDAYQKLAMETMEELEWCLDQLETIQTYRSVSDMAST
KFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQNEVEIPSPTSKTREKKKQQKQQLMT
QISGVKKVSHGPSLSSSSIARFGVKTDKEELLSKELEDLNKWGLNIFSVSEFSNNRPLTC
IMYAIFQERDLLKTFKIPADTFVAYMMTLEDHYHSDVAYHNSLHAADVAQSTHILLSTPA
LDVTGLTAAPLWLKLHVLLMNHLYFPFSSSERIPLSHCGHFLKSQVCRNRISYDGENSQE
SFKRHGLLTLVCFFQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRNWYQSMIPQSP
SPPFYDQSTHGHSGGTGGPGGGEKFQFELTLEEEDLDGMEKDGDAEEDEEEEELDEEEEE
EDSLGDSRSPPLDYLDGQENDKEGMIEPTTAIEIVTHEASPTDT
>A0A8D4UCL8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQAVLLDSQVYGVPHGQLSQHQLDLLKETLEKNPARYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLSPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELYSDGSIRTEVKRIQQAEFLPNMQEEGY
>A0A3Q4IH86|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Neolamprologus brichardi|TrEMBL
MSTQFKRMLNRELTQLSETSRSGNQVSEYIANTFLEKQHDVEILSPPPKEKEKKKRPMSQ
ISGVKKVTQSPGLAPASIPRFGVNTPHENLLAKQFEDIDRWGMDIFKVAEYSGNRPLTVT
MYTIFQVVFTDLEIIAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAV
GFKLLQEENCDIFQNLSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLG
VLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMKERFTQGDRERDRGMEISP
MCDKHNASIEKSQVSFIDFIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMIPRSPSP
STPEEHQFQFELTLEEEEEEEEEESGKTVARLTFFENVYKVCKRRFFSKAPDLKTV
>A0A857K1W0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pediococcus pentosaceus|TrEMBL
MKIAATSDNHFDVNKIDENQMAQKQAEYLLKQHVGVYLIAGDLFNKFNRSMQYVEKLQEL
VGEHTKVFFIAGNHDMLNDIDYNQLESNLSPLYLHNQFYDVPGTKWRIIGNNGWYDYTFA
DNVDKTTEQFWRWKKSFWIDTGIEQPMSDIERMNIVLKQTEQQMQQASRRKVLFMTHFAV
RHEYIHYSEDARFWNMINGMAGSRRMETLLETYQPELVISGHLHHHFKPLAKSNGIYYNN
SVGYHNNRINEWNSDDFFTEWTQRLLITDLK
>A0A1V0RQ36|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Roseovarius mucosus|TrEMBL
MARFLHLSDLHVVPEGQLVSGRLDTGRLLQEAVDTLRTRLDAIGPLDAILVTGDLSEDGS
AESYAIARRELERLGQRMLVVPGNHDGRETFRSAFSDLPEIRPTGLIDWVSDIADTRVIG
LDTLIEGKGGGILRAESLAFLDQALAETGGRQVVVALHHPPLRTGIRFMDAIGLENPDAL
RLVLERHQAPIWVLSGHVHGVYHGLLGRHPVVTAPSCCSAFALDLRQEAPVGFMTGPTGC
GLIDTGPGGVWTELPLRHGDGPFAF
>A0A7Y8FXK0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas reactans|TrEMBL
MPSVSTVSPDAPALLVQLSDSHLFAEADGTLLGMNTRESLQGVIELVRAQQPHIDLVLAT
GDLSQDGTLESYQQFRDMTRQIDAPARWIPGNHDEPQIMSHAAVHSDLLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPNRHHLVCFHHHPVPIGCAWMDPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERLVGFAFTVDYGSNGY
>A0A0A6QNC3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio caribbeanicus|TrEMBL
MKVTSNSSDSSIKLLQITDTHLFEATDGSLLSVNTGESFKAVVNAIVEQECRFDALLATG
DISQDHSEASYQCFERGIEPLLKPCFWLPGNHDYKPNMTSVIPSPQIQQVDHVLLGEHWQ
MILLDSQVVGVPHGRLSDKQLALLDEKLAQYADRHTLVLLHHHPILVGSAWLDQHTLKDA
DDFWQVVQKHNNVSAVLCGHVHQDMNVMHHGVRVMATPSTCVQFKPNSDDFALDTTSPGW
RELVLKADGQLETYVKRLPAGCFQPDFSSAGY
>A0A182NJW4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles dirus|TrEMBL
MDEDAEVDVGCFKMKSFFRKYQSKSMESLCKAPSKAGVLTVKQLESMPQAERTRPARRYS
LIGTPPTSLDYPPDQHGEQAEKSSRPSFCDIDPDGERKRIPQAGPLAGVDGVKSPHNGES
LITGSKLTTELINSPEPRRRSLPPERSQSNAPSSDDDNESEQPVYYRTNSAPVFRPRSYG
RRSNGLKVFRFPDILEESPLEQPTTLSAREWRRFGAFRSLPADSIEPAFRQQILADYDVH
FYEYDEPAARYEAPARETVTFAAVEPTPGTSGHQWHAASDASDGKRHHQLVEIVVENGPG
EGCYVEEIVVPSLSEEEVSEIERLVSDLKFPNLLPPNPVIKILIAFCKNDPVFEALVNAS
HRLSLEPTFVKSAETAIDAFQNPSSGGHHIIIVDARYPRLLEAEALGRSIRNSKGSQHTT
MVAVVKKSVFEKDDTAVISLLDVGYNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQ
ALYTALHRSREAVIITDDTLRAQYANRASERVLNMKLDEIVGRSLNDLVTADISNILSHT
SRYKDYDGYLTTRRKSQESSQIHVRAVPVSCIGRNPTHLVLVLESSSSALVSSNAIGEAL
QTLPQGKEVPRGSLHSIRRGSFDVRSIASDGLRRTSLAKLSSLPLEAPITKVLSLLAQVQ
ENCSLEEAKLLDRVMEFLKREGLYSPQMKEIRTEDPVATDLIGALLTQGPTNILSSRRSS
NDSIIRGGGRPSTGSIVFNKTKESSQLSDLLQTALDWDFEIFKLEDLTEKRPLVCLGLEL
FRRFDVYNTFNCDEMTFKLWLIEMEKYYHSENTYHNSTHAADVMQATAVYLQQLSNRELK
IMDRMDEATALIAAATHDIDHPGRSSAYLCNSDNTLALLYNDICVLESHHAATTFRLTLG
DDKINIFKHLDRDMYKLARSIIVDMILATEMTRHFEHLAKFVSVFGTDVESKEPLAPDND
DNQILVRRMLIKCADVSNPTRPLKFCVEWARRIAEEYFMQTDEEKRKNLPIVMPMFDRTT
CSISKSQIGFIEYIIHDMMDAWNSFIEMPEIIRYMEFNYSQWKLFEEQGINTLSDIKRKQ
ISLTEEAPSTISLEEKF
>A0A0D9R449|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chlorocebus sabaeus|TrEMBL
MEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAEPERP
PHRPIERADAMDTSDRPGLRTTRMSWPSSFHGTGTGSGGAGGGSSRRFEAENGPTPPPGR
SPLDSQASPGLVLHAGVATSQRRESFLYRSDSDYDVSPKTMSRNSSVTSEAHAEDLIVTP
FAQVLASLRSVRSNFSLLTNVPVPTNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
PSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGVKKLMHSNSLNNSNIPRFGVKTD
QEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYML
TLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDDNLKLLTSSDLPTLASQSAGITGSS
DSPASASRVAGTTDSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRK
MVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVPPPPIMLVSNSRP
QVSLTKKIQKTSRARWQAPVVPATREAEAGEWRKPPRQCDKTRSLQKIHQVGFIDYIVHP
LWETWADLVHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPPPDKFQFELT
LEEEEEEEISMAPIPCTAQETLTAQGLSGALDTTMAREASPAQESLDVMAQDESLEAELE
EVYLTQQAQSTGSAPVAQDEFSSQEESVVAVSQSSPSALALQSPLLPAWRTLSVSEHAPG
LPGLPSTAAEVEAQREHQAAKRACSACTGTSGEDTSALPAPGGGGSGGDPT
>A0A846C4C0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Okeania sp. SIO2F4|TrEMBL
MSQFPVLVAQITDTHLFADPTQGKMYGVSTETSFLKVLEKLGQLQPQPDVLLLTGDISQD
ETPESYQRLASLISPLNIPTYWIAGNHDRLPIMEQQLNCAPISAKKSFEIGGWYFLLLNT
NVPGCVYGQVCPESLEWLEFQLKMIGNKPVLITLHHPPIKINSEWMDRIILHDPELLLNI
INRYPQVKIVLSGHVHQEFETEINGVRYLTTPSTCIQFEPENSEFVLDKKPPGLRLLTLY
PDGNYTTKIERADYIYEFDMAASGY
>A0A8D1WSH4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sus scrofa|TrEMBL
MFMDRGLLRIARSPGCMSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYR
SDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKR
SPMCNQPSINKATIT
>A0A7Z2T187|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio astriarenae|TrEMBL
MKVSSVISDSLEVVKLLQITDTHLFSDEEGALLNVNTRDSFQAVVEMIQAESVEFDAIVA
TGDISQDHSAHSYQRFLDGIAPLVKPCFWLPGNHDFQPSMGEVLPSNQVQAVEHTLLGKH
WQVVVLDSQVVGKPHGRLSDQQLDLLDSKLSEHSARHTLVLLHHHPVLVGSAWLDQHTLK
DSDDFWSVVEKHQNVKAVLCGHVHQDFDHKRGDVRVMATPSTCVQFKPRSTDFALDNQAP
GWRELSLHACGKVETRVKRLNSTKFMPDFASGGY
>A0A4R0DLE6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. ANC 4910|TrEMBL
MTLKQPHDQQQDWTIIQISDTHLMNQDDLEFVHMNPELSFHRVMAQIQHEYPHADALIHT
GDLAQIPVPETYQRYLDFMQTTGFQHYQVPGNHDNEEFFPFHDQKNKVHAIPMGNWCLVL
LNSAVKGKIDGWIDTEQLKQLDHILSLHAKQYILIACHHHPFEMQSRWIDQHILKNTEHL
TDVLAKHSNVKLVLCGHVHQASENQWHGIHFLSTPSTCVQFKPHSDDFALDDEAPGYRVV
QLKANGEFTTQVHRTQPIQKKINIEITGY
>A0A6S6ZEV9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter pestifer|TrEMBL
MLIAQITDLHMRTPGDKAYGIIDPAAFLGPAVRALNALTPRPDCVLITGDLTDLGRPHEY
QALRDHLQALEIPYFLLPGNHDDRAQLRAAFPDHAYLQGDGPFIQYAVETYPLRLLALDT
VVPMKSHGELCQDRLDWLATRLAEQPDRPTLVLMHHPPFLTGIEHMDAIGLLAGASELER
IVSRFPNVERVLCGHLHRTIFQRFGGTIASTCPGTAHQLALELGPRPVLQYVMEPPGYQL
HWWQGKSLVTHHAVIGEYPGPYPFA
>A0A0S7GWN9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
MRRNNSRLFNVTERHWDSSEPASSVELLQDPDVRYAVKRVFSGNVQLPRLSCRPSAQERA
QDGAPPEPAAPPTRSIRHSRSLGTLTSCFDVENGLSVPRNPLDAQSSSSSGLVLQVNYPH
SQRRESFLYRSDSDFDLSPKGPSRNLSSTSDLHSEDMIVTPFAQVLASLRTVRSNFALIT
GQQDRAASKTRSSGSNPPSMCKTSLAGLCRCQRGFADQYPIVNIELNDLELEAPSLWS
>A0A0S7GZ15|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
MRRNNSRLFNVTERHWDSSEPASSVELLQDPDVRYAVKRVFSGNVQLPRLSCRPSAQERA
QDGAPPEPAAPPTRSIRHSRSLGTLTSCFDVENGLSVPRNPLDAQSSSSSGLVLQVNYPH
SQRRESFLYRSDSDFDLSPKGPSRNLSSTSDLHSEDMIVTPFAQVLASLRTVRSNFALIT
GQQDRAASKTRSSGSNPPSMCKTSLAEEPHQQLAIETLDELDWCLDQLDTLKTRNSVSEM
ASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKPDDMDIMSPTTKEKDKKKHPMSQ
ISGVKKATHSLVPSTIPRFGVNVSQEEFLAKELEDIDRWGLDIFKVAEYSGKRPLTVTMY
TIFQERDLLKTFKIPADHFINFTEPYVSVI
>S5IZ24|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio parahaemolyticus O1:Kuk str. FDA_R31|TrEMBL
MQSSNDSIKLLQITDTHLFAADEGSLLSVKTADSFSAVVNEVLRRKVGFDYILATGDISQ
DHSAESYQRFADGIAPLQKDCYWLPGNHDYKPNMGSVLPSPQIQSAEHVLLGENWQLILL
DSQVVGVPHGRLSDQQLTLLEEKLTEFPERHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFDNVKGILCGHVHQDMNVIHKGIRVMATPSTCVQFKPNSDDFALDTTSPGWRELE
LHTNGDITTHVDRLPEGQFQPDFSSNGY
>A0A6C7C2U3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae serovar 55:k:z39 str. 1315K|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQHEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCTNFTLDTIA
PGWRTLELQANGSLETEVHRLQDTRFRPDTASEGY
>A0A1C6YUU1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hafnia alvei|TrEMBL
MESLFQLTVARGAPVRILQITDTHLFAGEHETLLGVNTYRSYHAVLEAIHAQSRPYDIVV
ATGDLAQDHSVAAYQHFAKGIATLNKTCLWLPGNHDFQPAMVDTLADAGVDPAKHMLLGD
HWQIILLDSQVFGVPHGELSEYQLEWLDRTLSLYPARHSLILLHHHPLPSGCTWLDQHSL
RNAHMLGEVLQHHPLAKTLLCGHIHQDLDLEWQGRRLLATPSTCIQFKPLCTNFTIDTLS
PGWRYLDLHPDGTLTTELHRLEGTEFRPDLDSDGY
>A0A080IIG6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli 1-250-04_S3_C2|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A509E3W4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Thalassocella blandensis|TrEMBL
MRIFAVSDIHIDYQENKEWMFQLSKTDFQQDVLLLGGDISDDLSLITACFQHLSRCFYKV
FYVPGNHDIWDAKKRFNHSIAKFEFLLQLAQEHGVCTQREVVRATKSQAHTREQETIERI
ASLHHLEAVPESTGIVSALEEFGHDKGDTYTAFENGESGGVESFAGRKSEDSISDDAIEI
VPLYSWYDFSFGEPAPTLRRNWMDFHRCHWPEEIKSEDDICDYFLSLNEENLYVSFHRVI
SFSHFLPRIDIMPSRIPQKHRIVYPVLGSVKLDEQLRKLGTDLHVYGHSHVQVDTSRDGI
RYLNAALGYPSEYWLDKRMTLVAELGT
>A0A8J5JXK4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homarus americanus|TrEMBL
MMEKLYNVSEAWWSACKRQGYDVVLKRNTEDAIKAFLDHTHDLIIIDARSSKHLSAENVC
RSIRAADHSQFTVLVGIVKKNFADRENATVGPMLKNGYNRIVTEVSTVGGVLNDLIQIEY
SELSSQSQLRAMQAVFSALDSCKEVVHITDTQHRIQYVNRACENILGYSLEDVAGRNLWE
LHISDSHKQDIRAFDHRSSVDFKTSLEHQRAGTDHRQPIDHKAGEPRVNLDISEAVNMQM
RRGREWEGVVTCRRKSGGAVHLPSKVIPVAPLTRKNEYYIYMSDTHALDRLEFSTVDHFH
PRGSIKSLRKGSHDIRSLNSDGSESTHFMDPTAFTLLGGPPVENDHPGRVLSAPVEREKF
TFNRNLNFESLNFVEGTQNIIRRQSLVKLHSLTIEAPITRVFNIINAAQENSPAYVAQAL
EKVLEILRSTELYSPQLISATPDNVRPVPADPVATDLLGGLLAQGPKPLLSGRRSSNDTA
VKVSQLSRQSLPALHQQASAAIRELLADDLSWNFDVIKLEKISDKRPLVWLGMSLMCKFH
VPDTLGCDEQTIQNWLTLIEANYHSDNTYHNSTHASDVLQATAYFLNQERLGQLLDPLDV
AASLIAAVVHDVDHPGKNSAFLCNTDNELAILYNDLSVLESHHAAVSFKYSHSDDRVNIY
KALDRDTYKHVRKSVIDMVLATDMTKHFEHLSKFINMSGNSKTPVKDDDTTSFDGARDSP
DLMSFGTPENLVIIKRMMIKCADVSNPMRPLHLYIDWAHRIANEYFNQTEEEKKRSLPIV
MPQFDRTTCSIPKSQIGFIDFFINDMFDAWDALADIPELIEHLRWNYQYWKEQEEAANAI
ITVSQNQPLCKADEEDEEEDETKEEDIADRENNNPAEDAS
>A0A145XD07|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter hormaechei|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEKRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQEAGISPAKCVFTGD
QWQILLLDSQVFGVPHGELSDYQLDWLETKLAAEPNRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLAKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLHADGSLTTEVCRLAGAQFRPDTASEGY
>A0A3Z8NH71|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVYRLADTRFQPDTASEGY
>A0A6M1RRT3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Grimontia sedimenti|TrEMBL
MRISHLPSQHSQTVRLLQITDTHLFADPYGCLLGVNTAASFQAVVGEIQSSQVEFDAIIA
TGDISQDHTAESYQRFVDGIAHWPQPCFWLPGNHDYQQEMQSILAQSTLQRCDSVLVGEH
WQLVVLDSQVKGVPHGRLSEEQLSLLDTALSTNKDRHTLVLLHHHPLPAGSAWLDQHQLH
NQEDFWAVVEKHNNVKGVVCGHIHQALDTEHKGRRVMAAPSTCIQFKPDSDDFALDSTNP
GWREIELHQDGTIITHVGRLKGTEFQPDMNSTGY
>A0A6J1Q3D8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Temnothorax curvispinosus|TrEMBL
MGCKISILECMRGKVEQEKSISSATSSSLVTSGKTDALDIVAEKDEKTPFQDSTLDENGD
YLTIKGPQDLSNYLLTTNVPSIVKILLVFSKDDPQLDILANTARRLGWSVSVAKDAEKAI
ELFQNRAHELVIIDHRGHHAAEGDAICRAIRSSPVYHNSVIIALVKKSYFMLDEKDHIVA
LNLLETGFSRALIECSHEGILINELVGIYTSSLLPRTQLAAAHALYLALDRCRDMVHVTN
DKNIVQFLNKVSEKLLGYKTEEMMGRNLSEIVFYENSALMEQQLAKGREFEGNMNCKRKN
NQMITINCRIIPFCITLKKPSHYIYVYDTTYLSENSAPISPASSPLHPPLKTSILSNARK
SSDVRSGVSEGRRRSSLQKLHTLQLEAPITKVITLLSNAVTDTTNPETAAQIDKAIDILK
TTELYVPHLKEDRAMYSDPVATDLVGALLASPRTAWESRRSSSDSARLSTIKAIAYPANS
RVQVKNFRGPQELMDILDNSLDWNFEIFKLEVLTEKRPLVFLGLTIMNLYQVPATLHCDE
KTLQNWLAIIEHSYNAENSYHNSTHAADVMQATARFMQSKRLKEILEPLDEVAALIAAAA
HDIDHPGRSSQFLCNANSRLAILYNDLSVLESHHAALTFKLSLSDDSVNIFKNLDRDAYK
LLRQNVIDMILATEMTKHFEHLAKFMNVCSARIGDGQETYSDSLDMSVVLQPDNVILVKR
MMIKCADVSNPTRPLKCCVEWARRIAEEYFNQTDEEKKLKMPVVMPMFDRMTCSIPKSQI
GFVDYIINDMIEAWDVFIDMPEIVGYMRHNYEKWKEYNEQGISTLQDVEKLQQHPEMQIP
RLS
>A0A5F1EUP6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGESRVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADSRFQPDTASEGY
>A0A377YZB0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pneumoniae subsp. ozaenae|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A0A6N8QDV4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLPLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A385ER57|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter baumannii WM99c|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIQQILKQHPEADAIIHT
GDLAQAPTPITYKRYINFMQTLGLPFFQTLGNHDNVDHFPLHNENHQQPVVVGLGNWRVI
MLNSAVKGKVDGHLSSEQLENLANLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFQNVKALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLNNDGSFETKVFRLENFKTRINTDISGY
>A0A0M2F7U1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium brasiliense|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIQARQDAFDLIV
ATGDLAQDHTLQAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGE
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPYPSGCTWLDQHSL
RNAHNLSAVLDRYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A4Y2FI34|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Araneus ventricosus|TrEMBL
MVNLIQWNARGLRNKALAKDSFLKADIVAIQETFLTPSVNFALPNKILYRTDRHNSPSGG
LLIGINKTFSSHLVNLQLPPSEVEVQAVRIIIESKPILIINVYSPHGNFESSFLENLYAS
LSPPFLIVGDFNIHHPILGSSRTSRSANVVLDWISTHNMCILNTSNPTYFKQGCHPSLLD
LSICSPDLLYETKWTVYNDTFDSDHCPVEISFNYGNSKGPSVRRRIHWGKFGTSLNSILD
RENDIHSIQSFEKLCNQEKNNNTLIQDMFSKKFPPWWSSECSYLLGQKRKFLRLAKQSRY
NPYWNRAKHIAAKLRKLIIHLKRSYWDKLCDNAGSSKTSFRIIRSLRSRDMPQQNAHRLI
ILEGSNLTSPLGQANAFGSMFGSSPISEGIPLDFSGSATPMDSEFSIRELLQSLPKKLNG
SPGSDGITGRMLRCLTLVNLKKILSLVNKIWLSGNIPPSWKHSVIIPILKLGKNASELKS
YRPISLTSVLCKTTERMICRRLTDFFLKENIFHPHHFGFLPFRSCESLQMMFFNTLLKAR
SNKEYIIAASLDISSAYDSVWPDGVVYKALQIGLSGHTARWIHEFLTNRTLQVRWSGKLS
ASFTSNRGVPQGCCISPYLFTIYLHDVFEIIPPGVTCLIYADDIFIICSDPSLQNVKTKL
QITIQKIQIWCQNWKLKLDPTKSTVVNFSNKRQTPNFQISVDNVYIPWSNNMKVLGIFFS
ANLSFNCHFNYVAKKALKRLGYLRALGGSNWGANTVHLLRLVNACIRSICEFGAHVTSYA
GSTSWRKLEVVHHNCLRFAAGLPRWTPIPVMFAETGEIRLRDRSLALSISFFLRHFALGD
NFSPIKKSNLCTLDGLRPSFKERFSGGTNWLNFLKDANVRIENFIPFVYPVELQQENTIS
FHTNDLPFQQSQIPYPTLCKLFDEYVNKEWNSSILIATDASKGEEGVSLAALNITYNRTL
TLKLHPMNSVFTAEGCAILIAIERFIQEADKSYILCSDSLSVLKSLESLHRKSPTISLQI
GSAIIRAIPRSTAIKLVWVPAHVGITINEQADEAAKAARISDVNIYPCISTEDLRKVIFR
VKADQGRIQWESTKYFPSFSHLPKTTKTPLLPRRKEILLTRLRTRSLPTKAILFKVGLES
SPLCRQCGIVDSNDHLLLSCTVFEQLRNNLRASLGIGALHYNWICTISTFNRRACSAALL
VFSKDDAQSDALKWAAEKLSCECTMAYTPEDATESYQNTHPHLVFIDSRQSKTFDYTALC
RAIHSIQGSQYSCLVAVVKKSAVDKEDGSIVSFLRSGFTRWFVENHNLGVCLNELIQIHH
TDISYLLKLRASQALFSALDSCREGIIVTNLDHNIQYANKASEKLLGYTAEDLCGKDAQT
LCRAESVKADIAESINMQVKKGKDWEGTLFHKRKSGENLPLWSRIQPVEIYSGQAEHLIH
VNECPFNEKPFSTETDLLPFVKAPRKGSCDVRSFSGETGLNRRQSFAKFHPMTLEPPITK
VINMILATQEHSPLFVVQALDRVLDILRSTDIYSPQFTGLRQNHADDQVASDLFSGLISN
SKQVIRRFSHEAFKGVPSSGTTQPPPLTPSTVPTLANAPPRVKELLENVTEWHFDIIELE
RVTEKRPLIWVGMSIFATFNACNLLNCDESVLRNWLSLMESHYHANPYHNSTHAADVLQA
TAYFLQKPRLKAIFDPIDEVVSLIAAAIHDVDHPGRNSAFLCNTGSELAILYNDLSVLES
HHSALAFKLTIGNEKVNIFHNLNKDTYKEMRRSIIDMVLATEMTKHFEHLSKFVNVFTKS
VEAEEDESLEPSSPDLSAMSTPENIVLVKRILIKCADVSNPARPLNSCKEWANRIAEEYM
SQTDEEKSKSLPIVMPAFDRTKCSIPKSQMGFTDYFVNDMFDAWDAFCDVPELMENIKTN
YEYWKQQEVLRQKGIEAQESTSNT
>A0A5M6BKF3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus seminalis|TrEMBL
MKNTFVYQTEKSIIKLLQITDPHLFKEEETALLGVNTQASFTQVLKEIQQENNTFDIILA
TGDLVQDGSDEGYRRFVEMVTPLNKPIFWIPGNHDFQPKMVEHLNKTPMESAKHLLLGKY
WQVLLLDSQVYGVPHGQLSQHQLNLLEEKLAQHTNRYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLGKFSNVKGILYGHIHQEVNAIWNGYQVMATPATSIQFKPDSHHFTLDNLQP
GWREIELHKNGSIYTQVKRIQEAQFLPNMQEEGY
>A0A7J5WXW7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gordonia sp. YY1|TrEMBL
MSTTNCTILQLTDTHIVPPGQLLRGVVDSARNLGEVLERIVASGRRVDALLLSGDLTDNG
DVRAYRRLRDLVEPAAGSIGAQVIYAMGNHDAREAFRIGLFDQPGDPDAPHDTVHLLRGT
RVITLDSTRPRRHDGWLEPEQLAWLRDEVATPAPSGTTVLALHHPPLRSAIAPIDLLRLR
EADRLAEALAGSDVRMIVCGHSHLTGGGSLAGIPVWVGPALAYRLDTLAPVGRHRGHIGY
GFSRIDVVDGTVVATAVEATPTETVYDADESQTLAALREPARQD
>W8BBA4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ceratitis capitata|TrEMBL
MYLKRHNKFSCRRNSTGTSGTTSSGGASKPEKRKSSIALTPDDESIERSLMDVKFPTVLP
PNPQLKALLVFHKSDNICEVVTEACHRQQLDVTVARTKEGALETLSSTSEEFYHLIIIDA
RSTKHLDAEYIARSIRHTNGHHFTTIIAVVKKSFFEKDEVLIALLDAGVNRCVPETTNLS
MCNIELKQILHSIVRPHNVMSTQQALYTALHRLKEVILITDNHLRIQYANRAAERLLNMR
LDEIISKPLADIFVSDVSTIMMHGRKNKEFDEILTVRRKGQEDVSMHVRVIPVACIGRTP
THYVFNLDVPGSHGDFVATLPQAREAPRGSQHSIRRGSVDVRSVASDGLRRTSLAKLTSL
PLEAPITKIINLLSQVQENCSPDEARLIDKVMEFLKREGLYSPQMKEIRTDDPIATDLIG
ALLTGPSLYSSRRSSNDSIIRVSGRQSTCMPAKMKATPHIMELLEESLSWEFDIFKLEEI
TEKRPLLYLGMEMFRRFNVFATLNIDENVCKGWLAIIEANYHSNNSYHNSTHAADVMQAT
GCFLTQLAAKDMGMDHTDEAIALIAAAAHDVDHPGRSSAFLCNSRNTLALLYNDLCVLES
HHASITFRLTLSDDKVNIFKNLDTESFKSVRSVVIDMILATEMTRHFEHLAKFVSIFGSD
EEPKDIVQSEEESSILIRRMMIKVADVSNPSRQPSYCIEWARRIAEEYFTQTDEEKSKAL
PIVMPMFDRNTCSIPKSQIGFIEYIIQDMMHAWDSFIDMPQLVTYMQINYSQWKKFEEQG
VHTLADVKSKQHSLSVKKSAK
>A0A7Y1FG32|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. WS 5019|TrEMBL
MPSLPTQSTDSSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIERVLQEQPQIDLILAT
GDLSQDGSEASYQRFRQLTSAIDAPTRWLAGNHDEIPPMQAACQGSELLEPVIDLGAWRI
VMLDSSIPGAVPGFLADSQLELLERALSEAPQRHHLICLHHHPVSIGCKWMEPIGLRNPD
ALFSVLDRYPQARTVLWGHIHQEFDQQRGNLRLLASPSTCVQFAPGSEEFQVDSEAPGYR
WLRLHADGKLDTGVSRVTGIHFEVDYSVKGY
>A0A3N0UFY8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lonsdalea populi|TrEMBL
MESLLTLPVARGARIRILQITDTHLFAGKQETLLGVDTYHSYHAVLEAIAARQHDFDLIT
ATGDLAQDQSLAAYEHFAEGIRRFNAPCVWLPGNHDFQPAMVDALALAGIAPSKHVLLGE
SWQVILLDSQVFGVPHGELSEYQLEWLERILSGHPERFTLLMLHHHPLPSGCTWLDQHSL
RNAHSLDDVLSRYPLVNTVLCGHIHQELDLDWHGRRLLATPSTCVQFKPHCTNFTIDNAA
PGWRYLDLLPDGGVETQVVRLEGNAFQPDMDSDGY
>A0A6S7E2R9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter dolens|TrEMBL
MSLRQSSFFLRFLTLGALAHVYVGARLIPDAGLDGPGSATAVLLLILSCILIPLGMLARS
SVHPPWGDRIAWVGLIAMGLFSSLFVLTVLRDALLLVTWLVSLATGPGLPWIDLRRVSAI
AVAALALAATLVGFYNARRRARVVTVEVPIRGLPTDLDGFTIVQISDIHVGPTIKRRYVQ
AIVDAVNELSPDVIAITGDVVDGSVEQLAAQASPLGQLRAPFGVYLVTGNHEYYSGAAPW
VAEFRRMGLRVLMNEHAVIHPAGLPVVVAGVTDYSAGAFDPRQRSNPAAALAGAPADALP
KILLAHQPRSAAAAAPLGYTLQLSGHTHGGQFFPWGFFVRFQQPYTAGLHRLGDMWVYIS
RGTGYWGPPKRLGAPSEITRLRLRPLR
>A0A0F1AVT5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter sichuanensis|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDHVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLHADGTLTTEVCRLTGAKFRPDTASEGY
>A7ZRR4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O139:H28 (strain E24377A / ETEC)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A502K1N4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus haemolyticus|TrEMBL
MKNTFVYQTEKSIIKLLQITDPHLFKEEETALLGVNTQASFTQVLKEIQQENNTFDIILA
TGDLVQDGSDEGYRRFVEMVTPLNKPIFWIPGNHDFQPKMVEHLNKTPMESAKHLLLGKY
WQVLLLDSQVYGVPHGQLSQHQLNLLEEKLAQHTNRYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLGKFSNVKGILYGHIHQEVNAIWNGYQVMATPATSIQFKPDSHHFTLDNLQP
GWREIELHKNGSIYTQVKRIQEAQFLPNMQEEGY
>A0A1W6M0Y4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio vulnificus|TrEMBL
MQHTSSDTLSENSIKLLQITDTHLFASDEGSLLSVKTLQSFQAVVEQVMARHVEFDYLLA
TGDISQDHSAASYQRFADGIAPLEKACFWLPGNHDYKPNMSSVLPSPQITTPEQVELNAH
WQLILLDSQVVGVPHGRLSDQQLSMLEHYLQASPEKNTLILLHHHPLLVGSAWLDQHTLK
DAEAFWQIVERFPMVKGIVCGHVHQDMNVMHNGIRVMATPSTCVQFKPQSDDFALDTVSP
GWRELTLHANGEISTQVQRLASGSFLPDFTSSGY
>D4BWU7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia rettgeri DSM 1131|TrEMBL
MDSQLEVTAKNSKVVRILQVTDTHLFANTENTLLGVNTYRSYQAVLDAISEENLPIDLIV
ATGDLVQDQSPQAYQHFADGIARIPAPCVWLPGNHDYPPAMVKTLRIAGISSAKQVLIGD
EWQILMLDSQLQDVPHGELSEQQLEWMKASLDAEPERTTLIMLHHHPLASGCTWLDQHSL
RNSHILADYLKSYSNVKAMLCGHIHQEMDENWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELSINEQGQRHITTRVHRLDTREFSPDLDSDGY
>A0A7K0C474|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Actinomadura macrotermitis|TrEMBL
MAIIAQLSDIHLAAGRDGRVDDASGPVRALRTAVSSLLSLPERPDAVVLTGDLADGGLPA
EYARLHALLSPLPMPVYPMPGNHDDPAALREAFADHPALAGSGDGPVQYAVDVAGVRLVC
CDSTVPGQPHGAMDAGRLAWLDEALAAAPDAPTVVATHHPPYPIGIRFIDDMRFLDPAGF
AEVVARHPQVVRIISGHVHRGSAGSLAGRVATTCPSTYRQLFLDLSKPGRAAVTGEPAGF
AVHLVTGDGQATTHFVPTGNYRPLMDVE
>F4NIA2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli D9|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A6L6GQ25|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia sp. J316|TrEMBL
MDSLLKLPVASGSRVRILQITDTHLFAGKHETLLGVDTWASFDAVLDAIAAQQRHYDLIV
ATGDLAQDHSIEAYQHFAEGIARLPAPCVWLPGNHDFQPAMFTTLAASSIADQKQVLVGD
HWQIVLLDSQVFGVPHGELSDYQLEWLECALAAEPQRHTLVLLHHHPVPSGCSWLDQHSL
RNPHMLDVVLQRYPLAKTLLCGHIHQELDLDWQGRRVLASPSTCVQFKPHCTNFTIDAEP
PGWRWLDLYDDGRLETQVQRLATRMFNPDLDSEGY
>A0A8B2TZS0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aggregatibacter segnis|TrEMBL
MLNTYQYNTQQDVFRIVQITDPHLFKDTNGELLGINTQASFSQVLSEIQQQQYDYDLVLA
TGDLVQDNSDEGYLRFRQEVKALNNKMVFWIPGNHDFQPKMFEILKEDSVSAKKHILLGD
KWQILLLDSQVQGVPHGQLEAEELDWLKLKLQEHPERYSLVVLHHHLLSTGSAWLDQHNL
RNANELAEVLAPFKHVKALLYGHIHQQVDSEWLGYQVMATPSTCIQFKADSNTFALDVAQ
PGWREIDLHADGHIETRVKRIQQASFLPNMQVEGY
>A0A7K0CMB1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces smaragdinus|TrEMBL
MSRAAQFLRSLTRRLRLPRPFVRALGLVLVTLIGAWLGLLVVGSVRTSVGPMETQMTLRP
SFSGGTKINVSPLGALRLDTHRAPIRLDVDVDQLDPDRSRALVAHPERLSGLEDEVAGDI
RSGTIDLAARSCVAVLCGATALGLAVYRTPRRALAAGGLALTLLAASAGTAYATWNPKSV
LEPRYSGLLTSAPGLVGNARSIVSDFDVYQRELARLVTNVTTLYEATSTLPAYQPDPTTM
RILHVSDIHLNPASWGIIRSLVTQYEVDVIIDTGDTMDHGSEAENRFLEPIAGLGAPYVW
VRGNHDSAATQKAMERQKNAIVVDDARTVTVEGLRIAGIGDPQFTPDRSVRAAGDPAEIA
AGRELADALRPEVSGGPQRADVAIAHEPLCVQQVDGLVPLALAGHKHNRKQHDLPGGTRM
MVEGSAGGGGLRALEQGVPEKVTASILYLDRDSKALQAWDEITLGGLGLTEAEVSRHLPE
ENTPGPSPSPSGSSSSSG
>A0A2N0VZH9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rahnella sp. AA|TrEMBL
MESLFKLPLVNGAKVRILQITDTHLFAGEDETLLGVNTFNSYRAVLDAIKAQQRDVDIIA
ATGDLAQDQSVEAYHQFARGISELTAPCVWLPGNHDFQPAMVNALQDAGISPSKHVLLGE
HWQIILLDTQVFGVPHGELSEYQLEWMERCLNQYPERFTLLMLHHHPLPSGCTWLDQHSL
RNAHMLANTLVNYPKVNTLLCGHIHQELDLDWYGRRLYATPSTCVQFKPHCTNFTIDTVA
PGWRYLDLYPDGRVETEVFRLETSEFHPDTESDGYE
>A0A109DB33|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio toranzoniae|TrEMBL
MELLHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAVLA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLSEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DAEQFWGVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVSTQVRRLPHGQFLPDFDAAGY
>A0A2R8ARG4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudoprimorskyibacter insulae|TrEMBL
MTRIVHISDLHFGRDRPELHEPLLSHINGLKADLVVVSGDLTQRARTRQFRQARRFLDRI
EAPLLCVPGNHDIPFFNPLMRLLHPFLPFKRHISPATEQVVQVASGPVVGVNTVDPKAWQ
RGALRSSSLARLARAFERPDGQGLAIAVMHHPPEQGEGAQKTPMLGAASALMQLRDCGTD
IILCGHMHVWRVSPVRTAGGVLLVQAGTGLSSRLRGHPNDLNLLILSGQAVQIERHAAEG
KQTEFRCISRSAFYKPAGMWRSRKGI
>A0A378NC98|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mannheimia haemolytica|TrEMBL
MHEYIKLPVTGVIKLLQITDPHLFSNPEETLLNVKTVKSFSAVIEQINKQAKQYFDLVLA
TGDLIQDHNIAGYHYFAQITNSLNSPIVWLEGNHDVQPSMSEILAQYKHILPHKQILLGE
QWQLLMLNTQVVGMPYGELSYSQLKWLEEKLAQYPQRFTLVALHHNILPTNSAWLDQHSL
KNSNELSEIFAKFKNVKAIVHGHIHQQVDDIWHGIPIYATPSTCIQFKPNCDQFTLDLQP
QGWREIELHENGTIETVVKRLNSNDFLPNVNAIGY
>A0A3L8BUC6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ketobacter sp|TrEMBL
MVRDATQPSIRIVQLSDCHLFKSTEGKLLGLNTEQSLALVMDLIQDQQHAIDLVLATGDL
SQDGSGESYARFHKWMEVFSCPVYWLPGNHDLTDIMANHQAAQRMSPCVIDAGNWQIIML
DSTIRGKVPGNFTESELRFLEKSLQASQGKHVVIALHHQPVPVGSAWLDQQIVGNAAEFF
KVVDQFSNVRCIIWGHVHQVFETERNGVKLMSVPSTCVQFQPNSQDFAVDKESPGYRWID
LHADGTHGTGVSRVTGVDFVVDYSVKGY
>A0A366IAH6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Brenneria salicis ATCC 15712 = DSM 30166|TrEMBL
MESLLTLPVASGARIRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKAQQGAFDLIV
ATGDLAQDHSLEAYHHFARGIRQLVAPCVWLPGNHDFQPAMVDALAQAGIAPSKHVLVGD
KWQIVLLDSQVFGVPHGELSDYQLEWLERCLQSQPDRYTLLLLHHHPSPSGCTWLDQHSL
RNAHHLDAVLERYPRVNTILCGHIHQEMDLDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLMPDGRLETTVYRLSGNEFLPDMNSDGY
>A0A1H4DXC7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lonsdalea quercina|TrEMBL
MESQLTLPVARGARIRILQITDTHLFAGKQETLLGVDTYHSYHAVLEAIAARQHDFDLIA
ATGDLAQDQSLAAYEHFAEGIRRFDVPCVWLPGNHDFQPAMVDALALAGIAPSKHVLLGD
HWQVILLDSQVFGVPHGELSDYQLEWLERLLDRHSNRYTLLMLHHHPLPSGCTWLDQHSL
RNAHSLDAVLSRYPNVNTVLCGHIHQELDLDWHGRRLLATPSTCVQFRPHCTNFTIDNVA
PGWRYLELLPDGGVETQVVRLEGNAFLPDMDSDGY
>A0A7U4KUK2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. PSNIH1|TrEMBL
MDSLLTFPAAPGSAIRILQITDTHLFAGKHQSLLGVNTWASFDAVLDAIAAQQHEYDLII
ATGDLAQDHTVEAYQHFVAGIARLQKPCVWLPGNHDFQPAMVNTLAEAGIAADKHVLLGE
QWQLLLLDSQVSGVPHGMLSDYQLEWLAASLARFPGRHSLILLHHHPVPSGCTWLDQHSL
RNPHQLEAVLQAFPQAQHLVCGHIHQELDLHWQGRRVLASPSTCVQFKPHCTSFTIDTLA
PGWRWLTLAADGSLETEVNRLQSDMFRPDLDSDGY
>A0A5C9A215|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Parahaliea maris|TrEMBL
MFHGLKRLDLTHDGPSVRLCQFTDCHLGAELGGRLLGMDTDHSMLAVVEQARRDGRSADL
VLATGDLADGGAPAAYRRLQSALAAFCPRQFWLPGNHDDCAAMQAVPGSERIMSGDIRVG
AWQIILLNSQVPGEIGGEIGPMQLRALDEALSGASEAGLHSLICLHHQPVAIGCAWLDEQ
MVADADALFAITDRYPGVKALLWGHIHQEVDRQRGSVRLLASPSTCVQFAPGSEDFQADD
LPPGYRWLELHGDGRIDTGVSRVEGVTFEINLQQRGYL
>O70285|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus musculus|TrEMBL
GGGSSRRLEAENGPTPSPGRSPLDSQASPGLMLHAGAATSQRRESFLYRSDSDYDMSPKT
MSRNSSVASEAHGEDLIVTPFAQVLASLRNVRSNFSLLTNVPIPSNKRSPLGGPPSVCKA
TLSEETCQQLARETLEELDWCLEQLETMQTFRSVSEMASHKFKRMLNRELTHLSEMSRSG
NQVSEYISNTFLDKQHEVEIPSPTPRQRPFQQPPPAAVQQAQPMSQITGLKKLVHTGSLN
INVPRFGVKTDQEDLLAQEL
>A0A4R0HZG5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kosakonia quasisacchari|TrEMBL
MESLLNLSLAGEPRVRVLQITDSHLFAEKHETLLGVNTWESYQAVLEAIRSQQRECDLIV
ATGDLAQDHTAAAYQLFADGIASFDAPCVWLPGNHDFQPAMYSALQEAGISPAKRVFIGD
HWQILLLDSQVFGVPHGELSEFQLDWLEKKLTDSPQRHTLLLLHHHPLPSGCGWLDQHSL
RNAGELDNVLQRFPQVRYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLDLYPDGTLHTEVCRLESTQFRPDTASEGY
>A0A6M1ZW31|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chlamydiae bacterium|TrEMBL
MRFSFFLLFLIPFHMGFCSIDEQQFHKAEGREYKGLTYEEEGRWNEPFFFIQMADCQLGM
FDHDLCWDKEILLLEQAVDHINRLRPKFVIVCGDLTNAKPFKKAYDEQVYDYKRIMSRVS
HDIPLVCVCGNHDVGNKPSAKKIKAYEDNFGSHYFSFWVGGVQCFTLNSSLFFNPSKAEE
MFREQREWIETELVKTLSLNPKHRLVFTHHPWFIRDPEKLSLPIFEIPLERRMDIMNLLV
DQNVTACFAGHYHRNAYGVYKGMEVVTTSALGKPIGKDPSGFRIVKVFEDRVEHEYFGID
EVPESVSLQSE
>A0A6M1ZPN6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chlamydiae bacterium|TrEMBL
MIQGYLAFALSTLGIYPRYIEPYLLRTTYLDLPLSPDLEGLRIVHFSDLHFHRGMSSRFL
RKITSRIRRERPDLILATGDFLCYSQLEDSERLKAFLCTLQAPLGCYCSLGNHDYDAYVS
RNSEGNYDVVTPPNFMEGAFRAFKALIQKRKRSGEITQKVKSVSLNAQFCALLKETPFSL
LENSSITLPIGLNLVGLGDYSLDRCRPETGFAGYNKKFPGIVLTHNPDSVPLLQSYPGQL
VLSGHTHGEQIHFPFPKALRKLSQKLARLENSEYTRGFFSVGDKKLYVNRGLGSHRPFRF
CSPPEILVVRVKENADR
>A0A093D5W3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Tauraco erythrolophus|TrEMBL
ELTPLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMH
SSSLNNTSISRFGVKTEKEDHLAKELEDLNKWGLNIFNVARYSHNRPLTCIMYAIFQERD
LLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEI
LAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFQ
NLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVL
RNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQV
>A0A7Z2H3M4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. SO10|TrEMBL
MDSLLTLPAQDGSDIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIEVQQRQYDLII
ATGDLAQDHTVEAYQHFVAGINRLPKPCVWLPGNHDFQPAMVDTLADAGIKSDKHVLLGD
HWQLVLLDSQVFGVPHGMLSEYQLEWLHTALSKYPERHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLQHFPRARNLVCGHIHQELDLDWHGRRVMASPSTCVQFKPHCTNFTIDTLA
PGWRWFTLQPDGTLQTEVNRLQSDMFRPDLDSEGY
>A0A0T9UB53|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia intermedia|TrEMBL
MQKQGHHLESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQ
HPFDLIVATGDLAQDHSVAAYQNFAKGISRLPAPCVWLPGNHDFQPAMVDALASAGIAPS
KHVLVGDNWQVLLLDSQVFGVPYGELSEYQLEWMERCLMAHPERYTLILLHHHPMPSGCT
WLDQHSLRNAHMLAAVLTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTN
FTLDTVAPGWRYLDLLPDGRLETEVRRLASDEFCPDMDSDGY
>A0A2T2XXS5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kluyvera genomosp. 2|TrEMBL
MESLLNLPLAGGASVRVLQITDTHLFAEKNETLLGVNTWESYHAVLQAIHASARDVDLVV
ATGDLAQDHSAAAYQHFAEGIASFTAPCVWLPGNHDFQPSMYSTLQDAGISPAKRVLVGE
HWQILLLDSQVFGVPHGELSDFQLEWLEKRLAEAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAASLDNVLVRYPRVKHLLCGHIHQELDVEWNGRRIMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHADGSLTTDVCRLAGVKFHPDTASEGY
>A0A5E4L5B7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKLLALSDIHGNYSHVKSICEKAGDFDAVLIAGDLTDFGPDEKALELLAMFTTPVLVVPG
NCDNPSLLGILDENKNTINLHNSIHEFGGFNFIGLGGSNPTPFNTPFELSEKKIGEYVGQ
LLSGLNGRIILLSHAPPRNTTDRLPHGNVGSEALARYLGRFDLIVCGHIHEARGIVRVNG
TQVVNPGMASRGQGALITINEDINTEFIDVK
>A0A508TZ23|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bradyrhizobium ivorense|TrEMBL
MMAAFRLAHLSDPHLPPLPAARLRDLAGKRAFGYLNWTRNRHKYHRRDVLDTLVADMQAQ
QPDHVAVTGDLVNLALEGEFNPARQWLEGVGPPADVTVVPGNHDAYVRATRHRFVAMFGD
YLRGDADGAATHFPFVRRRGPMALIGVSSAVPTPPLMATGWLGHAQLGELDKILAQLSRE
DAFRVLLVHHPLHSDGRAKRLTDAHQLLALLKRHGVELVLHGHDHIHSTMWFDGPERKIP
AIGVPSASALPRKHYPAAAYNLFSIERDGNGWRCEHTVRGFDSHDGIRELQQMRLC
>A0A8C1UM68|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyprinus carpio|TrEMBL
RVAVQQDFHGAPLSVCLCPDESYQKLAVETMEELDWCLDQLETIQTYRSVSDMASNKVRR
CSTSLLRAPLEVVKTVRGCLCSKARSRTSS
>A0A3S4JYC1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. arizonae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLVLQANGVLETEVHRLQDTRFRPDTASEGY
>A0A1A8V8P6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothobranchius furzeri|TrEMBL
LRQFKRMLNRELTQLSETSRSGNQVSNYIANTFLEKQHDVEILSPPSKEKEKKKRPMSQI
SGVKKATQSPSLASACIPRFGVNTPHESQLAKEIEDLSRWGMDIFKLAEYSGNRPLTVIM
YSIFQERDLLKTFKVPIDTFITFMMTLEDHYHMDVAYHNNIHAADVVQSTHVLLSTPALE
AVFTDLEIMAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQ
EENCDIFQNLSKKQKDSLRKMVIDMVLATDMSKHMNFLADMKTMVETKKVTSLGVLLLDN
YSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFTQGDRERDKGMEISPMCDKH
>A0A4P7PB42|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas viciae|TrEMBL
MPSVSTLTTADAALLVQLSDSHLFAEADASLLGMNTRDSLGAVIDLVLKQQPNIDLMLAT
GDLSQDGTLESYEAFRQLSGRIDAPARWIPGNHDEPQVMLKAAVKSTLLDPVVDIGNWRV
TMLDSAVPGSVPGFLAEEQLILLANALSEAPQRHHLVCLHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEVDRVREGVRLLASPSTCIQFEPGSEDFAVGSQAPGYR
WLRLWPDGRLETGVERVVGFAFTPDYESNGY
>A0A1J6YQE7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. houtenae serovar 50:g,z51:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A7W3ZWI1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. SR44-3|TrEMBL
MLNEPVSYSIAESDTVRLVQVTDPHLFADLEAQLLGVTTYQSFSAVLAMINQANHGQHLL
LATGDLSQDYSPESYQLFANTVKRVPVPCHYLPGNHDDARLMNLSVQGDHVFGQQRIVIG
KWQILMLDSTLIGKPGGYLGQRQFELIEQAIAQTPDKHVLLAMHHNPVLVGSTWLDQHCM
ANGEDLIEFAGQFKQIKGLVWGHVHQALDRQVPGRFGPLQLMATPSTCIQFKPQSANFAL
DGLQPGYRLLDLASDGSIHTQVYRLEGDDFSADNHANGY
>H2IUI6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rahnella aquatilis (strain ATCC 33071 / DSM 4594 / JCM 1683 / NBRC 105701 / NCIMB 13365 / CIP 78.65)|TrEMBL
MESLFTLPLVNGAKVRILQITDTHLFAGEDETLLGVNTFNSYRAVLDAIKAQQREVDIIA
ATGDLAQDQSVEAYHQFARGISELTAPCVWLPGNHDFQPAMVNALQDAGISPSKHVLLGE
HWQIILLDTQVFGVPHGELSDYQLEWMERCLNACPDRFTLLMLHHHPLPSGCTWLDQHSL
RNAHMLANTLVNYPKVNTLLCGHIHQELDLDWYGRRLYATPSTCVQFKPHCTNFTIDTVA
PGWRYLDLYPDGRVETEVFRLETSEFHPDTESDGYE
>A0A1C4EXG9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kosakonia oryziphila|TrEMBL
MESLLNLSLAGESRVRVLQITDSHLFAEKHETLLGVNTWESYQAVLEAIQAQQRPCDLIV
ATGDLAQDHSAAAYQHFAEGIARFSAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
RWQILLLDSQVFGVPHGELSEFQLEWLENKLSDSPDRHTLLLLHHHPLPSGCSWLDQHSL
RNAGELNNVLQHFPKVRYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTVA
PGWRWLDLYDDGTLHTEVCRLESTQFRPDTASEGY
>A0A7Z0I8Z5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. WMus005|TrEMBL
MDSLLTLPAANGSEIRILQITDTHLFAGKHESLLGVNTWSSYKAVLDAIIAQHRDYDLII
ATGDLAQDHSIEAYQHFAEGISRLPRPCVWLPGNHDFQPAMVDTLAASHINAHKQVLVGE
QWQIVLLDSQVYGVPHGMLSDYQLDWLDNALARFPQRHTLVMLHHHPLASGCTWLDQHSL
RNSHQLDAVLQRYPLARTLVCGHIHQELDMEWHGRRVLATPSTCVQFKPHCTSFAIDTVA
PGWRWFTLHPDGGLETEVNRLDTDAFRPDLDSEGY
>A0A380T7Q8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas wadenswilerensis|TrEMBL
MPQPSIPLRDAPVYLVQLTDSHLFADPQGTLLGMNTRDSLQRVIERVRDEQPRIDLVLAT
GDLSQDGSVESYTCFRDLTASLQAPARWLAGNHDEPLPMEQATQGTALLDPVVDMGNWRI
LMLNSAVSGSVPGLLDDGQLRLLEQALSEAPERHHLICFHHQPVPIECAWMAPIGLRNAD
ALFAVLKGYPQVRALLWGHIHQEWDQVRDGVRLLASPSTCIQFEPRSEDFKVGEQAPGYR
WLRLQPDGSIDTGVSRVTGFEFTVDYEGDGY
>A0A7U5ZRI5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae complex sp. FDA-CDC-AR_0132|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFVGD
HWQILLLDSQVFGVPHGELSDFQLDWLETKLSAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVQNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHPDGLLTTEVCRLTGAKFRPDTASEGY
>A0A6I2JPY4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacteriaceae bacterium RIT702|TrEMBL
MDSLLTLPARDGSDIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIEAQQQHYDLII
ATGDLAQDHTVEAYQHFVAGINRLPKPCVWLPGNHDFQPAMVDTLADAGIKSDKHVLLGD
HWQLVLLDSQVFGVPHGMLSEYQLEWLHTALSKYPERHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLQHFPRARNLVCGHIHQELDLDWHGRRVMASPSTCVQFKPHCTNFTIDTLS
PGWRWFTLQPDGVLQTEVNRLQSDMFRPDLDSEGY
>A0A6L6THS9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. TDA1|TrEMBL
MHVVQLTDAHLFADPAGTLLGLNTRDSLRHVVAQVQREQPAIDLLLCTGDLSQDASVASY
EAFRELTAGFGVATRWLPGNHDEARVMADIAQGTDLVQAVTDIGGWRIVMLDSAVAGATH
GLLEEAQLSLLEGALKTAGERHCLVCFHHQPVDIGCAWIAPIGLRNAQALFGIVERYPQV
RGLLWGHVHQPWDEMREGLRLLATPSTCIQFAAHSEDFKVSEEQPGYRWLRLHADGRLET
GVERARDFDVKLDFDSPGY
>A0A8I0M6U8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSAMNPDAVLLVQLSDSHLFADADVTLLGMNTRESLQRVIDLVREQQPHIDLVLATG
DLSQDGTLASYQQFRDMTAPMGAPARWLAGNHDEPQIMADAAVHSDLLEPVVDVGNWRIT
LLDSAVPGSVPGYLQDQQLQLLVQALSEAPNRHHLVCLHHHPVSIGCAWMEPIGLRNPDA
LFAVLDRFPQVKAVLWGHVHQEIDDQRNGVRLLASPSTCIQFAPGSDDFQVSDQAPGYRW
LRLRADGRLETGVERVKNFAFTVDYGSNGY
>A0A7M2JAD3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLNPDAPTLLVQLSDSHLFAEADAVLLGMNTRDSLQRVIDLVCEQQPRIDLLLAT
GDLSQDGTLASYQQFREMTAPFGVPARWIPGNHDEPQVMAHAAVHSDLLEPVVDIGHWRI
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPNRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVKAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFNVSEEAPGYR
WLRLHADGRLETGVERVKNFAFTVDYGSNGY
>A0A7Z6N073|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTVNPDAPALLVQLSDSHLFAEANGTLLGMNTRESLQRVVELVRRQQPHIDLMLAT
GDLSQDGTLESYQQFRALTAAIGAPMRWIPGNHDEPQIMAHAAVHSDLLEPVVDVGNWRV
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPSRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVKAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFSVSEQAPGYR
WLRLHADGRLETGVERLVGFAFTVDYGSNGY
>A0A5E7TCP9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEPHGTLLGMNTRDSLQKVIELVRAQQPHIDLILAT
GDLSQDGTLESYQQFRDLTRQLDAPARWIPGNHDEPQIMAEAAVQSALLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPQRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDQLRNDVRLIASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGRLETGVERVTGFDFTVDYGSNGY
>A0A5H6NWP8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Adjame|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDVDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A6P0NLS0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Okeania sp. SIO2C2|TrEMBL
MIFQPPVLVAQITDTHLFADPTQGTMYGLPTESSFVKVLEKLKQLQPQPDVLLLTGDLSQ
DETSKSYQRLASLLSPLNIPTYWIAGNHDNLPTMERVLNSAPISAAKYFEMGGWNFFLLN
TNVPGRVYGEISPESLEWLEYNIKMTGNKPVLIALHHPPVKINSEWMDKILLHNPEKFLS
IINRYPQVKIVLSGHIHQEFAKEINGIHYLSTPSTCIQFEPGNPNFFLDKQPPGLRLLTL
YPDGNYTTKIERINYIYECDMAASGY
>A0A8B4GII9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Serratia sp. JKS000199|TrEMBL
MESLFKLPVASGAAVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAIQAQRRDVDLIV
ATGDLAQDHSQEAYRHFAAGIAQLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKQVLLGD
NWQVLMLDSQVFGVPHGELSEYQLEWMERCLQAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAILLRYPKVNTVVCGHIHQDLDLEWQGRRLLATPSTCVQFKPHCTNFTIDDVS
PGWRYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>A0A8D2KCC8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Urocitellus parryii|TrEMBL
MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAEPERP
PHRPIERADAVDTSDRPGLRTTRMSWPSSFHGTGTSGGGAGGGSCRRFEGENGPTPSPGR
SPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSXNSSVTSEAHLYLLPPPF
QVLASLRSVRSNFSLLTNVPIPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDWCL
EQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPS
PTMKERGPQEAPXQRPSQQPLPLGPQFQPMSQITGVKKLMHSRSPNTSVPRFGVKTDQED
LLAQELENLSKWGLNIFCVSDYAGGRSLSCIMYTIFQERDLLKKFHIPVDTMKVTSSGVL
LLDNYADRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMC
DKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSFVPAGDQNGP
SPPPPFFLPLLSFFFFLYIL
>E2AGV1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Camponotus floridanus|TrEMBL
MGCKFSILEYIRGKVEQEKSISSETRSSLVVSGKTDVLDIVDNKYEKTFFEDITHDENGD
YLTLKGPQDLSNYLLTTTVPSIVKILLVFSKDDQQMDILATAARKLGWSVSIAKDADKAI
ELFQNRAHELVIIDHRGHHAAEGDVICRAIRSSPIYHNSIIIALVKKSYFMLDEKDHIVA
LNLLETGFSRALMECSHEGILINELVGIYTSSLLPRTQLSAAHALYLALDRCRDMVHVTN
DKNIIQFLNKISEKLLGYKTEEMMGRNLSEIIYYENFPLMEQQLSKGREFEGNMNCRRKN
NQMITISCRIIPFCTTLKKPTHYIYVYDTTYLSDNSASISPVGSPSHPSFRPSVLYTNTR
KPSEKSGEGRRRSSLQKLHSLQLEAPITKVITLLSNAVTDTNPETAAQIDKAINILKTTE
LYVPHLKEDKGIYSDPVASDLVGALLAPRTAWESRRSSSDSARLSTIKAITSPVNSRVQM
KNFRGPQEIAEILDNSLDWGFEIFKLEVLTEKRPLVFLGLTIMNLYQVPAKLNCDERTLQ
NWLAIIEHNYNADNSYHNSTHAADVLQATARFMQSKRLKEVLEPLDEVAALVAAAAHDID
HPGRSSQFLCNANNRLAILYNDLSVLESHHAALTFKLSLSDDSNLEQDVYKLLRQNVIDM
ILATEMTKHFEHLAKFMNVCSARIGDGQESYSDCLDMSVILQPDNVILVKRMMIKCADVS
NPTRPLKCCVEWARRIAEEYFSQTDEEKRLKMPVVMPMFDRLTCSIPKSQIGFVDYIIND
MIEAWDVFIDMPEMVGYMRHNYEKWKEYNMSIVPLVFRDWWDDIDRPISRLADQHFGTGL
HRDDLISNFTSGLGFNRAPLRSIFGNTYYRPWKNVTRHNSSGSSTIQLDNDNFQVILDVQ
QFSPDEITVKTVDNYVIVEAKHEERQDEHGYISRHFVRRYVLPPSHDLVNVTSTLSSDGV
LTVTAPKKNVTPAGTERVINVIQTGIPAAKPVPVETTTTTTTTN
>A0A1Z5L4C8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ornithodoros moubata|TrEMBL
MYLTVPTVRVLFVFAKEDNQYQALKWSAEKMHYECQLSNSADAAVDSYLNSQPHLIFVDA
RSRNAIDPVTLCRTIRGFRGSQFSCIVAVVKKGLAEKEDAAIIPLLKAGYNRWFTESSSC
GVCLNEMIQIEHNDLISLWKLRASEALFSALHFSRDGVIVTGPNHEIQFMNRAAERLVGF
SVEEMLGSNAQELHRTDSLKGDVVQTIAAQIKKGKEWEGTLFHKRKSGECIPMWSKIAPV
EIHTGMSDHLVYIKECPFFMEKPFSPDAVGMNRRQSFAKFHNMTIEAPITKVINMLVATM
ENSPPGVVQALDRVLEILRSTELYNPQLGVGGQGRAEDKMTSDLVSGLITTGQRPTGVRR
LSHENAVMKVNVTTTQQAGGSVPSLSTVPSKIRELLENDIAWEFDIIELETISGRRPLIW
LGLSLFSKMNVHASLNIDDSTIRNWLQVVEANYLDNPYHNSTHAGDVLQATAYFLLKLRN
KDIFDPLDEAICLISAVVHDIDHPGKSSSFLCNSDNELAILYNDRSVLESHHAAFAFKLT
LSDPKVNIFQNLDRDTYRTVRLSVIDMVLATEMTKHFEHLSKFLNAFQKPIQGEEAFDPD
STAEQDQANSLRSAENIILIKRMLIKCSDVSNPARPINMCIQWAHRIAEEYCAQTDEEKR
RGLPVMMPTFDRETCNTANSQTGFITYFVRDMFRAWSDFGEFPELMEYIEKNFIYWKDRE
TNRDN
>A0A4V1E6F8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio neocaledonicus|TrEMBL
MQSSSDSIKLLQITDTHLFAADEGSLLSVKTVDSFNAVVADVLRRNVAFDYILATGDISQ
DHSAESYQRFANGIEPLEKDCFWLPGNHDYKPNMGSVLPSPQIKAAEHVLLGEHWQLILL
DSQVVGVPHGRLSDQQLTLLEEKLAEHPERHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVERFDNVKGILCGHVHQDMNVLHKGIRVMATPSTCVQFKPNSDDFALDTTSPGWRELQ
LHACGDITTQVGRLPDGQFQPDFSSNGY
>A0A7L4ZNF7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kordia antarctica|TrEMBL
MLRFLVPIILILILELYTFFSIRALTSNKFILIGYWIVTFVIYGIIFYQMNVAEREGRFS
ISLGYTIAMALTFLIPKLFILAILFVEDIFRFFTSLFNYFQHNGMTVSEAIPSRRKFLSQ
LALGIAAIPFAGFIYGVFQGRYNYKVIKHTMFFDDLPEAFDGYKLTQISDIHSGSFDNRE
KIEYAVDLINEQKSDLILFTGDIVNAVAEEMNPWIDTFKRLEATDGLFSILGNHDYGYYA
YEDQKDIEENHKKIEKVHEAIGFDLLLNDKRTIEKNGQKLNILGVENWGASRHFPKKGSL
REASKDVADGEFNILMSHDPSHFDYKEMEVRTKEREDPAVITDEPNIINFEKKIQLTLAG
HTHGMQFGIEIPFLNLKWSPAKYRYPRWAGLYEEAGKYLYVNRGFGVLAFPGRVGIWPEI
TVIELKKRNKIA
>A0A6S5XU04|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLNAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLLESGISPAKCVFAGD
HWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPARNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLVNFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGNLTTEVCRLSGAKFRPDTASEGY
>A0A379G6Y2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia rustigianii|TrEMBL
MDSQLKVTANNPNVVRILQVTDTHLFADTENTLLGINTYRSYHAVLDAIAEQNLPIDLIV
ATGDLVQDQSPKAYQHFATGIEHIPAPCVWLPGNHDYPPAMVGTLKIAGISSAKQVFIGD
EWQILMLDSQLQDVAHGELSEQQLEWMKACLDAEPTRTTLIMLHHHPLPSGCTWLDQHSL
RNSHILADYLKNYPNVKAMLCGHIHQEMDEDWHGIRLLATPSTCVQFKPHCTNFALDCMA
PGWRYLELCIDENGHREITTHVHRLNTREFSPDLESDGY
>A0A2I8SDK7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter freundii complex sp. CFNIH3|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRAKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A8C9L9A7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pavo cristatus|TrEMBL
MESLPPRQPDYMSVCLFAEEPYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKVSGG
TGLLGSRPHRGSKWPRVLLCVRNGVKPCAVAWLGLSFGKGLMPF
>A0A644YVS5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MESKNDVRAIACGKTVVLEYGMKKRLHVLLLFCGCVAAAFFMGCSISFHPKTSLAAAEAT
PEPTSTQTPAPTATPVPTPFSIVWLSDTQSITYYNYPHAMEDMGRWIAEQRVPENILYVV
QTGDMVDNGFVPKQWDIFDECYNQFKDDIPYFAIAGNHDIGVKLQDYSAYLARPNVSSIP
RRNSFERGRAVYATFEAGGTKFLLLGAGWESEEMSVDWMNQVLKEHSDSVAILLFHSYIF
MDGSYTNQGQMMFEQVVVPNPNVRLVLCGHVSVSGARFEELDDNGDGVNDRKVTAMLYNY
QDFMDNCGQLRLLTFDPVSRSIDVMTYSPYTGRYFWDDYFKTVEFTLEDAF
>A0A645BCH2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MAGRCRFVGNYARMANMGKRNRWFLLVLAIVFFALCSACAAAPALPQAQPTLQPAQVSAT
PEPTLADTPEPTPVPTPFSIVWLADTQTMSYYNYPGALAKMGQWIADEKDGRNIRYVVQT
GDAVDEGWIAKQWKNFDQLYDEFRDKLPYFPIAGNHDVGMQWHGYGPYLARPNVRSIPRF
NSFEGGKAVFATFSAGGTDFLLLGAGWESELDAVGWMNDVLNRYPDRVAISLFHGYINAD
GTFTNIGQQMFDQVVSKHANVRLVLCGHVRGTGYRADDIDDTGDGKPDRRVNTMIYNYQH
YDQNCGQLRLLTFDPVSRSIEVMTYSPVSDYFFRDDYFKAETFTLEDAF
>Q5E2M1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aliivibrio fischeri (strain ATCC 700601 / ES114)|TrEMBL
MLSETLLNEESDSIRLLQITDTHLFAPEDGALLGVPTRKSFQSVVEQVLQRTPDFDAILA
TGDISQDHTVESYQHFVKGIIPLKKPCFWLPGNHDYKPSMGGVLPSPQISACEHLLIGQH
WQVIILDSQVVGVPHGALSDEQLTLLDNALSQHPQRHSLVLLHHHPLPAGSAWLDQHQLK
ESEQFWSVLAKHHNVNGIVCGHIHQELDRVVNGIRLLATPSTCVQFLPDSDDFALDSQAP
GWRTLDLLPNGDIETQVYRLKDCDFSADSEAGGY
>A0A0H3I1K7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium parmentieri|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKVRQEAVDLIV
ATGDLAQDHTLQAYHHFSSGIAQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLQGQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSAVLDRYPKVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMNSDGY
>A0A2C6DG69|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Budvicia aquatica|TrEMBL
MESLFQLPLARGSKVRVLQITDTHLFAGADETLLGINTQESFQAVLNAVAEQGHGYDLIV
ATGDLAQDHSLAAYDRFAAGIATLPAPCVWLPGNHDFQPAMVDAMAAAEILPSKLALLGD
DWFLILLDSQVLGAPYGELNEYQLDWLDRSLNQYPDRHALILLHHHPLPSGCTWLDQHSL
RNSHALAEVLDKHPLAKTLLCGHIHQDLDLDWNGRRLLASPSTCVQFKPHCTNFTIDDLA
PGWRFIDLYSDGSIETTVCRLEGDAFRPDMNSDGY
>B7Z6T1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|TrEMBL
MQGPPAPAPVPGPGSPRGSPRGSPGLFRKLLVNQSIRLQRRFTVAHPLCFDLENGLSCGR
RALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDLHGEDMIV
TPFAQVLASLRTVRSNVAALARQQCLGAAKGHGAEAGIGDARRAGLVPGSVGDAADPALG
GGDGLQQVQADPEPGVDPPVRNQPLREPGVRVHLPDLPGPADRGGAAQGDR
>A0A080VMZ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas aeruginosa|TrEMBL
MSRHSNTPATDASVLLVQLSDSHLFAEDGARLLGMDTAHSLEKVVERVAREQPRIDLILA
TGDVSQDGSLDSYTRFRRLSSPLDAPLRWFAGNHDEREPMQRATEGSDLLEQVVDVGNWR
VVLLDSSIPGAVPGYLEEDQLELLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGY
RWLRLHDDGRLETGISRVDDVVFEVDYDTAGY
>A0A8H9YME3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas tritici|TrEMBL
MPSVSTVSPDAPALLVQLSDSHLFAETDGTLLGMNTRESLQRVIELVHTQQPRIDLVLAT
GDLSQDGTLASYQQFRDMTAPIGAPARWIPGNHDEPQIMADAAMHSDLLEPVVDVGNWRV
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPSRHHLVCFHHHPVPIGCAWMEPIGLRNPD
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERVKDFAFTVDYGSNGY
>A0A3R9YQY4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella aerogenes|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLHDAGISPAKRVLLGD
HWQILLLDSQVFGVPHGELSDFQLEWLEHQLNAEPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGALDHILSNYPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGVLTTEVCRLSGAEFHPDIASEGY
>A0A1Y0P0P3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio anguillarum|TrEMBL
MNVSPTLDNSDSIKLLQITDTHLFAPDDGSLLSVNTVDSFHAVVAEICAQHVEFDAILAT
GDISQDHSAESYLRFSRGISSLEKTCFWLPGNHDFKPNMGAVFPSEQIQQSEHVLLGEHW
QMVMLDSQVVGVPHGRLSDQQLALLDEKLSTHHQRHTLIVLHHHPLLVGSAWLDQHSLKD
SDAFWNIVTQHRNVKAVLCGHVHQNMDKLHHGVRVMATPSTCVQFKPNSDDFALDRTSPG
WRELTLSADGQIETQVKRLANGAFQPDFNANGY
>A0A7Y2PNU3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter terrae|TrEMBL
MTLSNYNETQQDWTIIQISDTHLMNQEDLEFVDMNPEQSFHAVIEQIQQQYPNVDAIIHT
GDLAQVPVKETYTRYLAFMQRLGIPFYQIPGNHDDMDLFPFYHNQNQVHAIHFGPWSMVL
LNSAVRGKIDGWIEEEQLQQLDQILSKFQQQFVIVACHHHPFDMQSKWIDQHKLKNTENL
TDILARHTNVKAVISGHVHQDSLNEWKNIQFFSTPSTCVQFKPLSDDFALDEEAPGFRVL
HLKANGELQTEIYRTEKASQKINVEISGY
>A0A2X0PZ54|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lactococcus lactis|TrEMBL
MKIKKIVFSLIILIICTVIGVFYYAFKVEPYRLVVNEHQVNNTNSKENLKIVQLSDLHIK
KDFNADRLDKVIQKTNEQNPDFIIFSGDLYDNYSQYNENEAVISKLKSLKAKYGKIAIWG
NRDYGGGAVKEYANIMAESDFSLLRNENQVFTLDNGKKILFTGLDDALLGNPQFPSPNQM
AETSYDILLTHEPDEVSQYQNKGYELILSGHSHGGQINVPLIPQIQKKATALMSHANNYT
GGLYQLGANEKLYVNTGIGTTHLSARFGVAPEIAVLTF
>A0A5F1IYY9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. E1130|TrEMBL
MESLLTLPLAGESRVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADSRFQPDTASEGY
>A0A237FIT8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella boydii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7U4NKX9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter baumannii|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIQQILKQHPEADAIIHT
GDLAQAPTPITYKRYINFMQTLGLPFFQTLGNHDNVDHFPLHNENHQQPVVVGLGNWRVI
MLNSAVKGKVDGHLSSEQLENLANLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLYTLSPFQNVKALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLNNDGSFETKVFRLENFKTRINTDISGY
>A0A5X9Y4J3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Johannesburg|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A3A3M3U8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella montevideo|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A5X5NG43|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Colindale|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A735RBL1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. diarizonae serovar 48:i:z|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLVLQANGVLETEVHRLQDTRFRPDTASEGY
>A0A714LIW9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Typhi str. CT18|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A6I8TT60|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aedes aegypti|TrEMBL
MWLNGLCCGGLCGVGEVLKGGGQQHPYDDRQDQEELNPSSDCGTGNESKATLKARPHVVM
GCTPSILSSNNQQQQQQHQRKDSSSLYGGNLSNAGSGTLADNNGAGSNKFANNAALNQAQ
MLGYGPGGKEGIAGAGTGAGEKEYPKKDSIVSISGLGHVSVVSNVLRRPTIGSGTSSSSG
RYGHRQSSLALTPEEEPLDSYPRLISDLKFPNLLPPNPPIKILIAFCKNDPVFEALVTAS
HRLNFEPTFVKSAETAIEAFQNAATGGHHIIVVDARYPRIIEADVLGRSIRNSKGSQHTT
MVAVVKKNLFEKDDTAVISLLDVGFNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQ
ALYTALHRSREAVIITDDSLRAQYANRASEKVLNMKLDEIVGRSLNDLVTADISNILSHT
TRHKDYEGFISTRRKSQETLHIHVRAVPVSCIGRNPTHLVLILEQTSGTTLSALASDALQ
ALPHGKEVARGSLHSIRRGSFDVRSTASDGLRRTSLAKLSQLPLEAPITKVLSLLAQVQE
NCSADESKLLDRVMEFLKREGLYSPQMKEIRTEDPVATDLIGALLTQGPTNILSSRRSSN
DSIIRGGGRPSTGSIVFNKTRESSQLSELLNSALSWDFEIFKLEELTEKRPLVCLGLELF
RRFDVYNTFCCDEVTFKLWLIEIEKKYHSDNTYHNSTHAADVMQATACYLQQLSNRETKV
MDRMDEATALIAAATHDIDHPGRSSAFLCNSDDRLALLYNDICVLESHHAATTFRLTMAD
DKINIFKHLDRESYKLARSIIVDMILATEMTRHFEHLAKFVSVFGTDVDSKETTHDNDDN
QILIRRMLIKCADVSNPTRPLKFCVEWARRIAEEYFTQTDEEKHRNLPIVMPMFDRTTCS
ISKSQIGFIEYIIHDMMDAWNSFIEMPEIVRYMEHNYSKWKLFEEQGINTLSDIKRKQLT
LNSETTGSSSIEEL
>A0A5T5I3Z3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Paratyphi B|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A3V5VUV7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Ohio|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A4R6E135|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Scandinavium goeteborgense|TrEMBL
MESLLNLSLAGETRVRVLQITDTHLFAEKHETLLGVNTWDSYQAVLAAIRASQRECDLVV
ATGDLAQDHSSAAYQHFAEGIAGFDAPCVWLPGNHDFQPAMYSALQDAGISPVKRVFAGD
HWQVLMLDSQVFGVPHGELSEFQLEWLEQRLTETPERFTLLLLHHHPLPAGCSWLDQHSL
RNAGALDRVLMRFPRVKNLLCGHIHQEMDVDWNGRRMMATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLDGAEFRPDTASEGY
>A0A4Q7AMH2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter junii|TrEMBL
MTSQVSTLSQKDFVMIQITDTHLLEYPHLEFVGMQPEQSFHAVIDLMRQTHPEIDLIVHT
GDLAQNPTPLTYHRYLEYMHSLSIPFFQTPGNHDDINHFPFHEQDKTAPTVVELGNWCVI
LLNSAQPNRIDGKIADAQLQQLPKLLTQLHDRYVMIACHHHPFAMQSAWIDQHKLKNSSD
LLETIQPFSNVKAIICGHVHQDSITSWQGIEFLSTPSTCIQFKPKSEKFALDEEHPGYRY
IRLKANGEIETQVHRLSNSQRLSSSEVLGYD
>U9XU35|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli 113290|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A6J1XXR3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinonyx jubatus|TrEMBL
MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRNVQLPPLAFRQLEQAD
LKSESENIPRPTSLPLKILPLIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQAN
FVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFA
ALTNLQDRAPSKRSPMCNQPSINKATITESE
>A0A6S7AHZ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter deleyi|TrEMBL
MARVHTLARRNDPPAMLVQLTDCHLFGEPETVMLGVNTDASLRAVLRQIEADGKHPDLLL
ATGDLSQDGEPAAYRRLAATLGSAPALEGAQIRCLPGNHDLPAAMRQELPEWSMPVTDVG
AWRVVSLDTTVPGSNAGHLPDSQLDMLEAALAEAPGRHTLLAMHHNPMQIDSHWHDSMMI
DNPQALFKLLTRWPQVRVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNLA
PGYRWIKLYQDGSMATGVRRVQDALWHTAQAEPGSAQAA
>A0A2D4LEC3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micrurus spixii|TrEMBL
EMVQRPTNLPLRTLPLIAITAADTDTVSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVH
SQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALT
NLQDRAPSKRSPMCNQPSINKATITGKTP
>A0A7Y0W5A8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. WS 5532|TrEMBL
MPSVSAVNPDASVLLVQLSDSHLFAEADGSLLGMNTRDSLQRVIGLVREQQPQIDLVLAT
GDLSQDGTLESYQLFRDLTRQIDAPARWIPGNHDEPQIMAHAAVHSDLLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDSQLQLLAQALSEAPNRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVKAVLWGHVHQEIDRERNDVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERIKGFEFTVDYGSNGY
>A0A8E6VXT0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae serovar 6,7:m,t:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2G1ZLA7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp|TrEMBL
MLKEAISYSLEEKASVRIVQVTDPHLFADPNAQLLGVNTAKSLESVLNTIQAVDYPADLM
LATGDISQDYSGESYHNFVRAITPLDMPCHYLPGNHDDPRVMNLHMQGAKIFGQRRILAG
NWQIIMLDSTVRGKPGGHMSDSEIEIINSAVADQPDRHVLLVMHHNPILVKCRWLDQHCM
DNGSDFIEQVAQIPQVKGLLWGHVHQELHKEHQGMHGIIHLMSTPSTCIQFKPLSSYFAL
DAKQPGYRLLELKADGSMITNVYRVPGDKFAPDRNASGY
>A0A8E1S2Q1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea dispersa|TrEMBL
MDSLLTLPAANGSDIRILQITDTHLFAGKHQLLLGVNTWSSFDAVLDAIAAQQRDYDLII
ATGDLAQDHTVEAYQHFVAGIARLPKPCVWLPGNHDFQPAMVDTLAQAGIAADKHVLLGE
HWQLVLLDSQVFGVPHGMLSDYQLEWLDRTLRQFPDRYTLVLLHHHPLACGCTWLDQHSL
RNPHQLDAVLQNFPLARHLVCGHIHQELDLDWHGRRVLASPSTCVQFKPHCTNFTIDTVA
PGWRWLTLQADGTLHTEVNRLQSDLFRPDLDSEGY
>A0A729QN17|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Kouka|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A1M7LMX6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Morganella morganii|TrEMBL
METPLHLPVADGAAVRILQITDTHLFAGETDTLLGINTLSSYHAVLDAIVKQQLPADLIV
ATGDLVQDQSTRAYQRFTDGIARLPAPCVWLPGNHDYQPSMAQELAAAGISPSKQVLLGD
QWQILLLDSQVQSVPHGELSDDQLIWLDNCLAQQPDRYTVVMLHHHPLASGCTWLDQHSL
RNSHMLAEVLTRYQNIEGILCGHIHQDLDVMWNGIRMLATPSTCVQFKPHCTNFTLDTAA
PGWRYLELTTGDNPSLTTQLFRLDTDEFSPDLGSDGY
>A0A0D8L4H0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Morganella morganii|TrEMBL
METPLHLPVADGAAVRILQITDTHLFAGETDTLLGINTLHSYHAVLDAIVKQQLPADLIV
ATGDLVQDQSTRAYQRFTDGIARLPAPCVWLPGNHDYQPSMAQELAAAGISSSKQVLLGD
QWQILLLDSQVQGVPHGELSDDQLIWLDNCLARQPDRHTVVMLHHHPLASGCTWLDQHSL
RNSHMLAEVLTRYQNIEGILCGHIHQDMDVMWNGIRMLATPSTCVQFKPHCTNFTLDTAA
PGWRYLELITGDNPSLTTQLFRLDTDEFSPDLGSDGY
>A0A3B5AKD0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Stegastes partitus|TrEMBL
ILTLHTSFPQGQRRESFLYRSDSDYDMSPKTVSRNSSLASEGHTAEDFIVTPFAQVLASL
RSVRSNFTILANVSTPTVNPRATLSDQQYQQLALDTLEELDWCLDQLETIQTHRSVSEMA
SNKFKRMLNRELSHLSEMSRSGNQVSEYISSTFLDKQNEVEIPSPTLKDKPMSHISGVRK
LSHSSSLSSTSMPRFGVNTDHEDELAKELEDLDKWSFNIFRVAEFSNNRPLSCVMYAIFQ
ERELLKTFRIPVDTFVTYVMTLEDHYHGNVAYHNSLHAADVTQSTHVLLSTPALDAVFTD
LEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLHQENCD
IFQNLTKRQRQSLRKLVIDMTDPTDLTCSASCRCYTN
>A0A2R8BZY0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Palleronia abyssalis|TrEMBL
MKILFVSDLHLDHWADAGLDPLAAVPQSTWDQVEALFIVGDLTNAPEVGWPRVFNHVGRY
VPLDRVTVTPGNHDYYKFCLDGDDRLAAIATEAGVTFAQKAEILLGGCRILCCTLWTDFA
LTGERETARGMAMSEAGAQMNDYRYIRIGNEDFRRATPADTARVHADHRAWLEDRLAQPF
DGPTIVATHHAPHADCLVPPLSRVDAAYASDLSDLIMAHAPAAWIYGHTHTPRAFSVGQT
RLRNVSLGYPYQVPDAEIATQLLQGLAEVENGRFALTSTDGRSVDPEAET
>A0A0C2JPV7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio renipiscarius|TrEMBL
MKVTSDSSVTDIIKLVQLTDTHLFAAEDGSLLSVNTNDSFSAVVEGIHQQGFDFEFLLAT
GDISQDHSEVSYQRFAQGIERLEKPCFWLPGNHDYKPSMGSVLPSPQIVQTESTLLGEHW
QLILLDSQVEGVPHGRLSQQQLDLLDTQLRLHPERHSLVLLHHHPILVGSAWLDQHTLKD
AEQFWQIVEKHDNVRAILCGHVHQDMQVVRSGATVMATPSTCVQFKPNSDDFALDACSPG
WRELTLYADGRFETQVQRLADGLYLPNFDSSGY
>B7MAA7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli O45:K1 (strain S88 / ExPEC)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>D4GN45|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea ananatis (strain LMG 20103)|TrEMBL
MDSLLTLPAATESGVRILQVTDTHLFAGKHESLLGVNTWSSYDAVLDAIIAQQRDYDLIV
ATGDLSQDHSVEAYQHFVEGISRLPKPCVWLPGNHDFQPAMVDTLARAGINAHKHVLVGE
HWQVVLLDSQVFGVPHGMLSDYQLDWLDNALARFPLRHTLVLLHHHPLASGCTWLDQHSL
RNPHQLDAVLQHYPLAKTLVCGHIHQEMDVAWHGRRVLATPSTCVQFKPHCTSFTIDTLA
PGWRWFTLHNDGQLDTEVDRLSTQAFCPDLDAEGY
>A0A2T0B940|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clostridium vincentii|TrEMBL
MKKIKIIIIIVLIILLSVISDIFINKPRPIAKTEATITSNNDLAFAVLGDIHQNADHLQQ
TINDLYTINPGMDALVLNGDSVDQGIDEQYDLVKKTISKNKDLLPSTVIKNIGNHEFFNY
DAGRNSPEQVQTYINKYLEFSGEEKVYHDTWVNDYHFISLGSEDGNSDTADTTTAYVSEN
QLNWLKEKLAENYQKGKPIFVFLHQPLDYGERAWVGVKESEQIREILSQYPEVILFSSHT
HRDLVESSVILDQPFTIANTGAIDHTKIWDTNDGNGVRTEPNIKGLYIEVNGNTVVIKGR
DIKENQWIFTKEISKE
>A0A4Y7RXK2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pelotomaculum propionicicum|TrEMBL
MPERFIVCGDLHWRSVNPVARVDNFQEALTAKLYEVFQLAREHIASAIIIPGDIFDSSHL
SLSTIGDLAEILDKRPCAVLTVPGNHDEYAGNIDSLARTPYGLLARLELIWNVHATPWGS
PLGSVVVTGHGFNNETDRDKSQYSINRKRDRRAIIHLAHGMLLEKAPPFEMRHTLLSELE
ELPDLPDVLINGHYHAGMEVQWVRQTMVVNPGALCRLSASAEEMARPVQVAVLTVNGPGD
CRVEMAPLQCARPGCEVLTRDHIERKAETEERINRFLSLLAAEGESKFLEVRDIVSDIAR
REALPDAVVKDALDRIAKAREDLGKTA
>A0A2R8BL63|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Defluviimonas aquaemixtae|TrEMBL
MEETVQVGPIDRGFAPVTMFSVPRIVRHRIADARWTLPDLRIAVVSDLHVCRPWTSLAAL
RRIVNQVNALRPDLILLPGDFIADSNLPARHVPASAIVAELGRLRAPLGMAAVLGNHDWW
DCALSRETEFARNTVAEALEGSPVALLSNRSLGIEHGNGRFWIVGIDSQHARKHLKKQGF
EDPDIAFAGVPDGAPAILLAHEPDYFAVGDPRAFVQVSGHTHGGQANLFGWRPMTPSAHG
SRYAWGHIREAGRHLIVSGGIGYSGVPLRILQPPEITLVTLQRGG
>A0A6S7CW25|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter piechaudii|TrEMBL
MFHVFTGLISLYVIWRFVLPLSLSRPAKILLSLLLLGAAEHHLVTRNFFGSMASPEVPAT
LLMVLGWLFGALLLLAMLLLLRDVAGVVVYAFSRPRGRRLLAARAWGKGAAVLALMLSAI
GVWQAVRVPDVKTLEIALPKLPPELDGFRLVQLTDLHASRLLEAPWIDAVVKKANGLDPD
LIVITGDLVDGTTDARAADVRPLQALRARHGVYAIPGNHEYYAQYARWLPAFEQLGLRLL
LNEHVTLTPNGQRLVLAGITDKMAAAYDQPVPDAARALNGVPKTDPVILLSHRPIGAAQN
ARLGAGLQLSGHTHGGQILGPHLLTQLANEGYVSGQYEVDGMQMYVSNGTGLWPGFPIRL
GRPSEITQIVLRSPARVATP
>A0A6S7EEY9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter piechaudii|TrEMBL
MTRILQLSDTHFGTERKPVVEAALDLARSLNPDLVVVSGDITQRARRAQFAAARKFIERL
SLPVLTVPGNHDIPLINLFARALNPYGNYKRALGAVLEPVFENPGLLAIGVNTTRPRRHK
DGEISDAQIARVAQRLRQARPGQLRVVVAHHPVRAKVESDLSNLLNGRERALAAWAQAGI
DLVLGGHIHLPYVLPLSAGGLPAGWIVQAGTACSRRVRGSVPNSVNVITREGEGDQQICH
VERWDYAEATHVFAPVDKTLVTTVDRR
>A0A7T1M001|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia sp. 2.29|TrEMBL
MDSQLEVTARNAKVVRILQVTDTHLFADTANTLLGINTHKSYHAVLDAILEQNLPIDLIV
ATGDLVQDQSPEAYQHFAKGIERLPAPCVWLPGNHDYQPAMVSSLKLAGISSAKEILIGD
EWQILMLDSQLQDVPHGELSEQQLEWMKSCLDKRPQRTTLVMLHHHPLPSGCTWLDQHSL
RNSHILADYLKGYPQVKVMLCGHIHQEMDEYWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELSINEKGERHISTQVCRLNTKEFSPDFDSDGY
>A0A6P8WUM4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila albomicans|TrEMBL
MGCSTSALPNSASTTAAPGVGVGVGIGGNGGGPNAPLPPLDANEKDGSLLFCIKLRRSRM
RRCSCGAVTLQQQNGDGSTGSATCGDNIMCNQVLLNPQQTKNESDYEKLSTGKKDSIVTV
AALGNFTHSVVRRATGTGSTGTSGTSSSGGGRPGHRKSSLALALTPEDEPMDVYTRNLMD
LKYPTVLPPNPQLKALLVFHKSDSICEVVTLACQRHQLDVTLVKSKEEALDTLQKSYATA
QCYHLIIIDARSTKGLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDALIALLDAGVN
RCIAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYAN
RATERLLNMRLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMHVRV
VPVACIGSAPTHLIFNFDIPGGGMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLR
RTSLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRT
DDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGNSTRTAIVPAKMKANPIVMELLEESLS
WDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHN
STHAADVMQATGAFITQLTNREMVMDRMDEATALIAAAAHDVDHPGRSSAFLSNSNNPLA
ILYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEH
LAKFVSVFGSEVEPRELVQSEEETSILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYF
MQTDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWDSFIDMPQLITCMQIN
YSQWKKYDEQGVNTLADIMAKQPPVGNKPSNSK
>U3C277|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio azureus NBRC 104587|TrEMBL
MQLSNDSIRLLQITDTHLFAADEGSLLSVKTADSFRAVVEAILNQNVPFEYILATGDISQ
DHSAESYLRFAKGIAPLKQACFWLPGNHDFKPNMGHVLPSTQIKAEEHVLLGSHWQLILL
DSQVVGVPHGQLSQEQLTLLDTKLAQYPERHTLVLLHHHPLLVGSAWLDQHCLKQADAFW
QVIRQHRNVKGILCGHVHQDMNVMNNGIRVMATPSTCVQFKPNSDDFALDVTSPGWRELE
LHTNGNITTEVKRLADGLFHPDFTSSGY
>A0A2T3NAB2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium rosenbergii|TrEMBL
MQTFTLPQTNRDSVVLLQITDTHLFADDGGSLLGVATKDSFHAVLNAVDVAARPFDAIVA
TGDISQDHTEHSYQRFCDGIARWSQPCFWLPGNHDYQPSMQAVLPSPQIKPCHQVLAGEH
WQVILLDSQVKGVPHGELSQEQLEMLDEALSAHPDRHALVLLHHHPLPAGSTWLDQHQLH
NSEPFWQVIGRYPQVKAILCGHIHQELDRIHQDVRVLATPSTCIQFQPDSHDFALDQKSP
GWRYLSLHSDGRLETQVHRLEGHDFTPNFESAGY
>A0A1N6M418|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio spartinae|TrEMBL
MDVSFYTEHLDSIKLLQMTDTHLFASDEGSLLSVNTANSFKAVVQEVIARNVDYQLILAT
GDISQDHSQASYQLFVDSIEPLQKPCLCLPGNHDEQHAMKTILANSQITQPRHVTVGAHW
QMILLDSQVSGVPYGYISPEQLQQMDDMLRETQAKHTLILLHHHPLLVGSRWLDQHTLKN
SDSFWEILLKYPHVKGVVCGHVHQVMERDYHGIQVMSTPSTCVQFKPHTDEFALDLVSPG
WRELELHPDGQLTTQVGRVKQGLFLPDFSANGY
>A0A2H5V6B1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|archaeon HR03|TrEMBL
MKVLQASDIHGSMAAASALAEKAMNYDIVVLVGDITHFGAVPQAEPILATVAKSGRPVLF
VPGNCDHPSLLGWRPPNKNIINIHGAIVRQGGYDFYGLGGGNLSPFNTLIEFSEEEFESM
LSKFNPASESFILISHTPPFGVDADIGRGRHLGSTAIRKFVETKRPLAVCCGHIHEGRSI
SKIGETVVVNAGPAKEGFYASLEILGKEVKAELHSL
>A0A1S1FMF2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus sp. HMSC61B11|TrEMBL
MSNTFECESESEIVKLLQITDPHLFKDTNKELLGINTHESFSQVLKEIQAESFNYDVVLA
TGDLVQDSSDEGYLRFVEMVKPLNKSVFWLPGNHDFQPKMVEHLNQSPINASKHLLLGKH
WQVILLDSQVSGVPHGELSAYQLDWLKTKLAENPARHSLVVLHHHLLPTNSAWLDQHNLR
NAHEFSEVLAQFNNVKGILYGHIHQEVNGYWQGYQTMATPATCIQFKPDSNHFALDTLQP
GWREIELYPDGRIETRVKRIKQKTFLPNMEEEGY
>B4EW35|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Proteus mirabilis (strain HI4320)|TrEMBL
MESQLELSVDQQHTVRILQITDTHLFANVDDTLLGINTYRSYHAVLDAIKQQGLSIDLIV
ATGDLVQDQSFAAYQHFADGIARLPSPCVWLPGNHDYQPAMIDALNQAGILSAKQVLIGE
HWQLLLLDSQIQGVPHGELSDCQLDWLTRCLESHKERDTVILLHHHPMPSGCTWLDQHSL
RNSHQLAERVKDHPQIKMMLCGHIHQEMDEMWNGIRLLATPSTCIQFRPHCTNFSLDTVS
PGWRYLELSLSAQGKRNIDTQVHRLAGKDFCPDLDADGY
>A0A7X3CHW8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas salmonicida|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQVNEHPFDLILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQ
VMLLDTQVRGKPHGVLGDHQLAALDSALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRVASQVWRLPVGQFVPDPDATGY
>A0A1A8JN17|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothobranchius kuhntae|TrEMBL
MSSNELSVEMDSCIRTFKEHMHLELEPPKMPGVMGGKRGATSPKLSPRSSPRLFRKLMVN
KSIRQRRRFTVAHTCFDVENGPSASCSPLDPQASPGSGLVLHTNFPGHNQRRESFLYRSD
SDYELSPKSMSRNSSIASELHGDDLIVTPFAQVLASLRSVRNNFTILTNVQCPSSKRSPA
ATTQPPITKVCLPDEAYQKLAMETMEELD
>A0A2J8WPN6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pongo abelii|TrEMBL
ISFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRN
SSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTILTNLHGTSNKRSPAASQPSVSRVNPQE
ESYQKLAMETLEELDWCLDQLETIQTY
>A0A8H9WEP1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cycloclasticus sp|TrEMBL
MNVFLPEKCNASDIKVLQISDMHLFATTEQHLVGVNTEQSFLSILQLAQEESWPPDLIFL
TGDLSQDASEASYTRLIEHLTGLNIPCYVLPGNHDIPDTLTHIFSQQPVSYQPFLHHGKW
LFAFLDSETPGEEGGTLNEKAVEELQIEINQHPDKHVLICLHHQLKPVGSEWLDTMAVIN
PDSLIKVIDESPNVLGIIHGHVHQTFESDIAGIPIYAVPSTCFQFKPLCKAFAIDNIAPG
YRWLRLQATGQIQTDVIRLDKTPDNLDQHSAGY
>A0A2J8KKV9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pan troglodytes|TrEMBL
MAQQTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSKTARKSVSPKLSPVISP
RNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFVH
SQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALT
NLQDRAPSKRSPMCNQPSINKATITGSWIELNPYTLLDM
>A0A2J9SGR5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia enterocolitica|TrEMBL
MESLFKLPMASGAKVRILQITDTHLFAGEHETLLGVNTSRSYRAVLDAIIAEQHPFDLIV
ATGDLAQDHSVAAYQNFAKGISRLPAPCVWLPGNHDFQPAMVDALADSGIAPSKQVLVGD
NWQILLLDSQVFGVPYGELSDYQLEWMERCLVAYPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLVRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGILETEVRRLASDEFCPDMDSDGY
>A0A558BHG4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter vinifirmus|TrEMBL
MSDPKFARPLKVLQLTDPHLMARENGALLGVNTRESLSAVIEEALRSHGQPDLVLATGDI
SQDASVASYHYFGQKLEVFQCPFAWIAGNHDDSATMYAVADEFDARRRQFVLGGWHFVML
DSSVHGKVYGELSADELTFLDQTLSEHSGLPTMVCLHHHPIDIGSDWMNQIGLKNREAFW
QVIDRHTNVRGVIWGHIHQELQQQRNGVQLMASPSTCIQFARGSTDFAVEPLAPGYRWFE
LDPSGNITTKVCRAEQFRFNLDEGSAGY
>A0A1G5QLZ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus luminescens|TrEMBL
MESQFELPVVEGTTAKILQITDTHLFANKEDTLLGINTYRSYQAVLDAILKQNADIDLIV
ATGDLAQDQSLEAYRHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILIGK
HWQLLMLDSQVQGVPHGELSEYQLEWMKKCLDRYPERYTVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQGYSRVKAMLCGHIHQEMDLDWNGVRMMATPSTCVQFKPHCTNFTLDTVA
PGWRYLELSVADNGEFSLATQVHRLESNEFCPDLDSDGY
>A0A2K7SRB0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio rotiferianus|TrEMBL
MQLSSDSIKLLQITDTHLFAADEGSLLSVRTADSFSAVVQEILHRQVQFDYILATGDISQ
DHSAESYQRFAEGIAPLEKDCFWLPGNHDYKPNMGSVLPSPQIQSVEHLMLGEHWQLILL
DSQVVGVPHGRLSDQQLTLLEKKLAENPQRHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVNRFSNVKGILCGHVHQDMNVLDNGIRVMATPSTCVQFKPDSDDFALDTESPGWRELE
LHSNGDITTEVNRLPDGQFQPDFTSNGY
>A0A6G6J410|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas nitroreducens|TrEMBL
MPTQPTASDSVLVVQLSDSHLFAEENGRLLGMDTADSLTQVVRLVGEEQPAIDLVLATGD
LSQDGSVESYQRFREITASIAAPARWFPGNHDELGPMREAAADTDLLDPVIDLGAWRVIL
LDSTIPGAVPGQMTVEQIHLLERAIQAAPDKHLLISFHHHPVPIGSRWMDRIGIYNPERL
FAVLDRHPNVRCLLWGHVHQEIDRMRGDVRLLASPSTCVQFTPGSEDFCVDSPAPGYRWL
RLMADGRVETGVSRVTDIEFEVDYSIKGY
>A0A6L6G1G2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia sp. wls1919|TrEMBL
MLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLP
GNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLA
DAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDW
NGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQPDTAS
EGY
>A0A564G5X2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium dankookense|TrEMBL
MTWSPARRLWAFSDLHQEWPENAWDPATHAPPGGFDVAVVAGDVHMPLIRSLVWLAERLP
GVPVVYVPGNHDFWWNRGEERYTLADQMARGRELAARHGIHLLLDDAVVIGGTRFAGGTL
WTDFRLGSFSLTHRMRSAQGRFGMVDYRRIRTGSRSRQRVEPEEILALHRATRAFIDATL
AVPHEGPTVVVTHHAPHPDSLPGPHADMPWYYAADLRDLIHARAPDLWVHGHVHHAADYL
VGRTRIVCKPRGHADEASGFDPARVMCLER
>A0A3S0UJA0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Competibacteraceae bacterium|TrEMBL
MPTAAPLRIVQITDLHLKSTPGSRLWGVDVDASLSTVLARIQARHPQPDFLLVTGDLVGD
EPEAYGRVREFLEPLGVPVYCLPGNHDFPARMAQTLRHGLVRWQRSLIAGGWQIVLLDSS
VPGTPEGHLAYGELALLDTALVMHPELPALVCLHHNPVPTATPWLDTMTVSNGEALFAVL
DRYPQVRAVVWGHIHAEFSARRGAVQLLATPATCMQFKPNTPEPQLDDLPPGYRWFELYP
DGQLATGVERIEPTSRPLGLTRRVPA
>A0A6P3WNT6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dinoponera quadriceps|TrEMBL
MFNIPDKTDVLDIVGEKTPFEDNAHDDSDYLTIKGPQDVNAHLLTTSVPSIVKILLVFSK
DDQQMEILATTASKLGWSVSVAKDAEKAIELYQNRAHELVIIDHRGHRAAEGDAICRALR
SSPVHYNSVIIALVKKSYFMLADKDHIAALNLLETGFSRAMMECSHEGILINELVGIYTS
SLLPRTQLAAAHALYLALDRCRDMVHVTNDKNIVQFLNKVSEKLLGYTLEEMMGRNLSEI
VFYENFALMEQQLSKGREFEGNMNCKRKNNQIITINCRIIPFCTTLKKPTHYIYVYDTTY
LSENIAPISPIASPLHPPLRTSILSNARKHSDVRSAISEGRRRSSLQKLHTLQLEAPITK
VITLLSNAVTDTTNTETAAQIDKAIDILKTTELYVPHLKEDKIYNDPVATDLVGALLSSS
RTWDSRRSSADSARLSTIKPAMGPTNARISMKNFRGPQEIADILDSSLEWEFEIFKLEVL
TEGRPLVFLGLTIMNLYQVPAKLNCDEKVMQNWLSIIEYNYISENSYHNSTHAADVMQAT
ATFMQSKRLKEILEPLDEVAALIAAAAHDIDHPGRSSQFLCNANNRLAILYNDLSVLESH
HAALTFKLSLSDDSVNIFKNLDRETYKLLRQNVIDMILATEMTKHFEHLAKFMNVCSARI
GDGQVESYANSLDMSVVLQPDNVILIKRMMIKCADVSNPTRPLKSCVEWARRIAEEYFCQ
TDEEKKLKMPVVMPMFDRQTCSIPKSQIGFVDFIINDMIEAWDAFIDMPEMVGYMRQNYE
KWKEYNEQGISTLQDVEKIQQHPDLHIPRLPR
>A0A0F5V7Q5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium halotolerans|TrEMBL
MQTYSLPQDNSDSVLLLQLTDTHLFADATGSLLGVATKDSFHAVLDEVAAQLRPFHAIIA
TGDISQDHTPASYQRFADGIGRWVQPCFWLPGNHDYQPSMKSVLPSPQIKACDQVLAGEY
WQVILLDSQVVGVPHGELSPDQLQMLDQALAAHPDRHALVLLHHHPLAAGSRWLDQHQLK
NHPAFWQVVAQYPQVKAVLCGHIHQELDVLYQGVRVLATPSTCIQFKPDSNDFALDQSNP
GWRWLSLQANGEIETQVERVRQRSFTPQFDAAGY
>A0A6H1TUU1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oxynema aestuarii AP17|TrEMBL
MIQTLPLHVAQITDLHLFSDRNKRLMGIDTAASLQKVLSCLRQLRHPQDLLLLTGDLSQD
ETPESYELLVDLLSPWDIPSYWIPGNHDDPSLMEQILKTPPFFTDKVVEAGNWSLILLDS
TVTGWVSGQLSPSSLDWLEWQLERSRDRPTLIGLHHPPFAVNSEWIDSIALQNPDDFFAI
VKGHPQVKLVLCGHVHQNFCHQQKYLRCFTTPSTCVQFKPGSAEFAVDSAQPGLRLFNLY
PDGTWETKVMRVS
>A0A7I6Q518|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella sp. WP3-W18-ESBL-02|TrEMBL
MESLLNLPLAGGASVRVLQITDTHLFAEKNETLLGVNTWESYHAVLQAIHASARDVDLVV
ATGDLAQDHSAAAYQHFAEGIASFTAPCVWLPGNHDFQPSMYSTLQDAGISPAKRVLVGE
HWQILLLDSQVFGVPHGELSDFQLEWLEKRLAEAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAASLDNVLVRYPRVKHLLCGHIHQELDVEWNGRRIMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHADGSLTTDVCRLAGVKFHPDTASEGY
>A0A859PU78|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacteriaceae bacterium Kacie_13|TrEMBL
MESLFKLPLVNGAKVRVLQITDTHLFAGEDETLLGVNTFNSFRAVLDAIKAQQREVDIIA
ATGDLAQDQSVAAYHQFCRGISELPSPCVWLPGNHDFQPAMFETLHDAGINPSKHVLLGE
HWQIILLDTQVFGVPHGELSEYQLEWMERCLKAYPDRYTLLMLHHHPLPSGCTWLDQHSL
RNAHMLANTLVNYPKVNTLLCGHIHQELDLDWYGRRLYATPSTCVQFKPHCTNFTIDTVA
PGWRYLDLYPDGRVETQVFRLESTEFHPDTESDGYE
>A0A6L7ETR7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Raoultella sp. Lac1|TrEMBL
MESLLNLPLAGETRVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRPCDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLLESGISPAKRVLLGE
HWQILLLDSQVFGVPHGELSDFQLEWLEQKLAEEPERHTLLLLHHHPLPSGCSWLDQHSL
RNAGALDRALSAFPRVKHLLCGHIHQELDLNWNGRRMMATPSTCVQFKPHCANFTLDTLS
PGWRWLELHADGTLTTEVCRLNGVKFHPDIASEGY
>A0A366VYR6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Psychromonas sp. B3M02|TrEMBL
MNGVNQTVVNLVPDSTGDIKLLQITDTHLFADCEKDLLGIKTVASYDAIIEHAAKYAGQC
AAVLCTGDLSQDHSAQSYVDFSERIKTLSMPCYWLPGNHDMQEIMLPSLLAEGLAQAKQI
VSEHWQIILLDSQVSGVPYGHLSDSQLSFLQQKLQQYPDKHTLIAVHHHVLPVGAAWLDQ
HILKNNDQFIALISQFDNVNAVLSGHVHQSFDQVKNNVRYITSPSTCVQFKPQSDDFAVD
DKPPGYRYLVLKKSGKIDTQVERLNPGKFTTDENATGY
>A0A182Y2P7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles stephensi|TrEMBL
LALTPEEEPLDSCPMKSFFRKYQSKSMETLYKPAPVVLTVKQLESMPQAERTRPTRRYSL
LSAREWRRFAAFRSLPADSIDPAFRQHILANYDVHFYEYGELEPRYGTSPREPVAFSVDE
PKPGPSKEARSDGKQHQLADLVAGHGSQEGEEDETLPRLSEEEVQFIERLVSDLKFPNLL
PPNPVIKILIAFCKNDPVFDALVNASHRLSLEPTFVKSAESAIEAFQNPSSGGHHIIIVD
ARYPRTMEAEALGSVFEKDDTAVISLLDVGYNRCIIESPHVSICSSELRQIQHSLVRPQN
VISTQQALYTALHRSREAVIITDDTLRAQYANRASERVLNMKLDEIVGRSLNDLVTADIS
NILSHTSRYKDYDGYLTTRRKSQESSQIHVRAVPVSCIGRNPTHLVLILESSSTALVSSN
AIGEALQTLPQGKEVPRGSLHSIRRGSFDVRSIASDGLRRTSLAKLSSLPLEAPITKVLS
LLAQVQENCSLEEAKLLDRVMEFLKREGLYSPQMKEIRTEDPVATDLIGALLTQGPTNIL
SSRRSSNDSIIRGGGRPSTGSIVFNKTKESSELSDLLQTALDWDFEIFKLEELTEKRPLV
CLGLELFRRFDVYNTFNCDEMTFKLWLIEMEKHYHSENTYHNSTHAADVMQQLSNREIKI
MDRMDEATALIAAATHDIDHPGRSSAYLCNSDSSLALLYNDICVLESHHAATTFRLTLAD
DKINIFKNLDRDMYKLARSIIVDMILATEMTRHFEHLAKFVSVFGTDVESKEPLPPDNDD
NQILVRRMLIKCADVSNPTRPLKFCVEWARRIAEEYFMQTDEEKRKNLPIVMPMFDRTTC
SISKSQIGFIEYIIHDMMDAWNSFIEMPEIIRYMEFNYSQWKLFEEQGINTLSDIKRKQM
SLNEETASSISLEEKF
>A0A5A5RNM4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcystis aeruginosa NIES-2520|TrEMBL
MQRRKFLLISGSLGGFSLVACAHQILQPVTSKNPPESAVKQAQKAKKVKIIVISDLNSQY
GSTTYDPEIDRAIPLIINHKPDLVLCGGDMVAGQKSSLTAAAINAMWSAFDRHIAAPLRA
AKIPFAFTIGNHDASGALSAGKFIYAKERQLAMDYWQNPQHDTSLNFIDKTGFPFYYTFT
QNGIFYLVWDASTHLISGQQLNWAAKNLSSTDAKNAKMRLVIGHLPLYGIAVGRNRPGDY
LADAEQLRAFLEGYQVHTYISGHAHAYYPGKRGQLQLLHAGALGSGPRRLLNSEQAPRKT
LTIVDINPNQQETVYTTYDMKTQEAINITSLPPLIMAPNGQVLRRDIPSVN
>A0A8C0WA23|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Castor canadensis|TrEMBL
METFISFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSM
SRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKA
TITE
>A0A0D0R7G2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sp. L_1B5_3|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANDHSYEVILAT
GDLSQDHSPESYQRFASMMAPLGRPIYWMPGNHDDSPLMTEQLHAAGISESKQLVGEHWQ
VILLDTQVRGKPHGMIGDHQLEALDRALRQYPDRHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRIASQVWRLPVGQFVPDPNATGY
>A0A7M4FDL7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Crocodylus porosus|TrEMBL
MHVFPSPGISCQVGPAGLLGLCGACLRPQAGLAPGPHCLLLPPTEDAHQKLAVETLEELD
WCLDQLETLQTRHSVSEMASNKVSSAASPLALRGGGQGRWLQLPAPAVTRGVPLQVPGPA
RLLA
>A0A0T9P5R5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia pekkanenii|TrEMBL
MESLFKLPMASGARARILQITDTHLFAGEHETLLGVNTSLSYRAVLDAIIAEQRPFDLIV
ATGDLAQDHSIAAYQNFAKGISRLPAPCLWLPGNHDFQPAMVDALADAGIAPSKQVLVGD
NWQILLLDSQVSGVPYGELSDYQLEWMERCLVAYPERYTLILLHHHPMPSGCTWLDQHSL
RNAHMLAAVLLRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVA
PGWRYLDLLPDGILETEVRRLDSNEFCPDMDSDGY
>A0A7Y8VI77|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alteromonadaceae bacterium|TrEMBL
MTESRKQPPLRVLQLTDPHLMADEQGSLLGINTRDSLNAVIDEALSAHGQPDLVLATGDI
TQDASEAAYRYFGERLNEFGCPSLWIAGNHDDSAVLVSIAKEFQTGQKQLVQGGWHFVML
DSSVPGKVYGELDSTELEFLQRALVEHPDLPTMVCLHHHPVSIGSAWMDKIGLTNPELFW
QILEQHPQVRIVLWGHIHQDFHQQRNGVHLLATPSSCIQFETGSEGFAVEPAAPGYRWFE
LSASGEFQTEVGRATRFEFELDENSGGY
>A0A3Q9KGU0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter spanius|TrEMBL
MPRVHSLARRHDAPAMLVQLTDSHLFGEPDTAMLGVNTDASLRAVLRQIEADGKRPDLLL
ATGDLSQDGEAAAYRRFAAILGEAGGLSGAQIRCLPGNHDQPAVMRQELPQWSVPVTDVG
AWRVVTLDTTVPGSNAGHLSDSQLDMLEAALAAEPGRHTLIAMHHNPMQIDSHWHDSMMI
DNPQALFKRLTRWPQARVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNLA
PGYRWIKLYQDGSMATGVRRVQDALWHTALAPDDAQAA
>A0A6I1Z176|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces sp. RB17|TrEMBL
MTLSAKRPAGAGFRRTAVAAAAALTFAGAVTAAGPAFGSGADTATHGHAVTPDWLPDTPE
NWPLVVDYTRTPAQTVTRGLQHYSETYDTMGGRQHIQVLKADLTDSNLRVGMVEAGDTLT
NPADETPSSMAGRTHAVAGVNGDYFEIHASGRPLGGIISNGHILKSPKPGFASQLGVKPD
GTMVMGPETFSGTITDGTATRSLTSVNTVNDVASGGITEVTADLGETPGLSKPSTLVIGH
STDGGFVVDDVQAGVTTVPRLTTGRLGLLGAGDGGQWLGDTLHTGDTVGITTQLSPDNDV
TQLISGVDMLVKDGKVYQDPTGTPPSGANPETAVGITKDGKHAIVVAIDGHGGASTAFGV
TPEQAAGYLVAHGAYTALLFDGGGSTGMVSRAPGADRADVVNTPSDLPGNTERPVADGIF
FYSTAKEAGPAVQVRVNGGKAVTTVAGGSIPLSVYSVDRFANPAAGTAHVRVEPAGLATY
EDGKLTAHLTGTGRIIASNGKAFTSEKLEVVGKLDTLTVTPDKADLDNGATQQLALSGTV
KGGGEVQIPAEAATWKVGPDNLGSVDSHGLFTADADKGGLADVSATVAGATATASVAVGS
VSKTIDPMSSLDVWRLSNNTTGKPATLSADPGVVPPGSTESGSLKLDYSMPAGAGVKQLV
LSPKATLKTDTDNGQVPTGIGVWIKGDGNGIELAEKYIGVNGSSTTLYPTYVTWKDWHLA
VAQLPAGMQFPLTISFIDFLAISPSTSYGGSLNVGGLQALYSPRPVTAPAYHAIPKNPDW
LSFEEDSAHFAKKGTTLLAGDDAHMLASDPGSVSSNVMDSITKRLPTLTPQARPDAAQFL
GDMSDDGKPADLQYAKSKMDALGIPERDIVGNHEITQGADAENGNYSDAFGDTHYAYTQG
AARMIVTDNSHGSLQSSDPFQDPSGAQYPWLVRQLTDTTAKDVLVITHMPAYDPHPAANS
QFTDRWEAQMYLRLVQRYQQTHPKQHVIMLYGHARGFAEQILNPEGESVTTAEGGIPQFT
FADLGMPAYAPADQGGIYHFGLLRIGDDGDLQYSVEPALASITVNGPKDPIANGDHVTLT
ATGDQITGDNIAPLTIPIADPASHAWTSSNPKVASVDPSTGALTAHRSGTVTVSVTSGGI
TGSSLVVVR
>H2FVC5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oceanimonas sp. (strain GK1 / IBRC-M 10197)|TrEMBL
MTLSTLPLGPRAGNGVLELSQITDTHLFADRDGELLGVATWHSCRAVVDAMKEELAGCHA
ILATGDLSQDQSAESYRHFVGMMAELTPPVFWLPGNHDEAPLMQAELDAAGIGQAKHLLG
EHWQVLLLDTQARGHTHGRLSDDQLALLDTAIDRYPNHHLLVAVHHQAVPVGCAWLDQHN
LRNADELGARLARHRANRVVLCGHVHQGFDEVRGGIRYLASPSTCIQFKPLSDEFALDHT
APGWRQLSLYPDGRLSTRVWRLPPNAFVPDFSARGY
>A0A5I2G2T6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Agama|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPVMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDVDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A515BJ11|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter tandoii|TrEMBL
MTLKQSHDQPQGWTIIQISDTHLMNQDDLEFVHMNPEQSFHRVMAQIQHEYPHAHALIHT
GDLAQVPAPETYQRYLSFMQGTGFAHYQVPGNHDSEEFFPFHDQQNKVHAISMGNWCLVL
LNSAVKGKIDGWIGTEQLQQLDLILNQHAEQHILIACHHHPFEMQSRWIDQHILKNTEHL
TDVLAKHSNVKLVLCGHVHQASENQWHGIHFLSTPSTCVQFKPHSDDFALDDEAPGYRVV
HLKANGEFSTQVHRTQPIQKKINIEITGY
>A0A7Y3XR98|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. SbB1|TrEMBL
MSPPDQSRPVHVVQLTDAHLFADPAGSMLGLKTRDSLRHVVAQVRREQPLVDLLLCTGDL
SQDASVASYEAFRELTATFAAPTRWLPGNHDEAQVMAHVAPELVQAVTDMGTWRVIMLNT
AVHGATHGFLEDGQLAVLKEALKDAGERHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDI
VEGYPQVRALLWGHVHQEWDEVRGGRRLLATPSTCIQFAARSEDFKVSEEQPGYRWLRLH
ADGRLETGVERALDFAVKLDFDSPGY
>A0A7W2GFB6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. MD195_PC81_125|TrEMBL
MPSVSTLTAADPALLVQLSDSHLFAEADGTLLGMNTRESLQKVIEQVLKQQPRIDLMLAT
GDLSQDGTLESYQLFRQMTAQIDAPARWIPGNHDEPQIMAQAAVQSALLESVVDVGNWRV
TLLDSAVPGSVPGYLQDDQLQLLARSLSEAPERHHLVCFHHHPVSIGCPWMEPIGLRNPE
AFFDVLDRFPQARAVLWGHVHQEIDRERNGVRLMASPSTCIQFEPGSHDFKVGEQAPGYR
WLRLLPDGRLETGVERVTDFEFTVDYGSNGY
>E3BQG1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio caribbeanicus ATCC BAA-2122|TrEMBL
MKVMPRSSLEDAIELLHITDTHLFGDVDGSLLSVNTLDSFKAVINGVMNQNSSFDVILST
GDISQDHSAKSYELFEEHIIPLKQHCFWLPGNHDFKPSMEALLPSRQVKQSTHVLLGDHW
QMILLDSQVVGVPYGHLAEEQLELLEEKLSASPERYSLVLLHHPPVLVGSQWLDQHTLKN
SDDFWKRVSKYPNVKGIICGHVHQEVDVYCHNVRVLATPSTCVQFKPNSDTFALDALSPG
WRQITLRNNGDLSTSVRRLTQGQFQPNFNSTGY
>A0A4Q2R577|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae complex sp. 743-2DZ2F-22B|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEKRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGD
QWQILLLDSQVFGVPHGELSDYQLDWLETRLAAEPNRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDGVLAKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLAGAQFRPDTASEGY
>A0A2K5C6G6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aotus nancymaae|TrEMBL
MASNKFKRILNRELTHLSETSRSGNQVSEYISQTFLDQQTEVELPTVTTEEPPKPVSQIS
DLHGLCHSASLSSATVPRFGVQTEQEEQLVKVDQGLVPGSFTHLYTGQWDTNKWGLDVFK
VAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLLLEGHYHADVAYHNSLHAADV
AQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGNHHLAVGFKLLQAENCDIFQNL
STKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYPDRIQVLQS
LVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGF
IDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQSKIPRSPSGLTNPERGGPDRFQFGL
PLEEAEEEEEEEEEEGEETALDKEALELSDTELPPEASPDPGDLPLDNQRT
>A0A6N6K3V3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter pasteurii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLNWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A7U9NTJ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. AS-PWVM4|TrEMBL
MDSLLTLSAASGADIRILQITDTHLFAGKHQSLLGVNTWSSFDAVLDAIEAQQRDYDLII
ATGDLAQDHSVEAYQHFVAGIARLPKPCVWLPGNHDFQPAMVNTLADAGIAADKHVLLGD
YWQLVLLDSQVFGVPHGMLSEYQLEWLEKTLAKFPERHTLVLLHHHPLASGCTWLDQHSL
RNPHQLEAVLQNFPRARNLVCGHIHQELDLDWHGRRVLATPSTCVQFKPHCTNFTIDTVA
PGWRWFTLKSDGTLHTEVNRLQSEEFRPDLDSEGY
>A0A8B7G949|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microcebus murinus|TrEMBL
MGCAPSIRISEARAVYRGKEAEVALGPAGPPPSGGPCLTQGHRTAALPPARGASLADSEP
RDGSGKKVAVAEVQFGPMRFHQDQLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTREAQA
VLACFLDKHHDIIIIDHRYPRQLDAEALCRSIRSSELSENTVIVGVVRRVAREELSVMPF
LAAGFTRRYIENPNIMACYNELLQLEFGEVRSQLKLRACNSIFTALEKSQEAVEITNEDH
IIQYANPAFETTMGYQAGELIGKELGEVPINEKKADLLDAINSCIKIGKEWQGVYCAKKK
NGDNVQQNVKIIPVLGQGGKIRHYVSIIRVCTSNNKAEKISECVQSDTNTDSQTGKHKDR
RKGSLDVRAVASRSSEVSSQRRHSSMARIHSMTIEAPITKVISIINAAQESSPMPVTEAL
ERVLEILRTTELYSPQFGAKDDDPHANDLVGALVSDGLRRLSGNEYVLSTKSIQQVSSSI
ITPISLRDVPPRIARAMENEESWDFDIFELEAATHNRPLIYLGLKIFARFGICEFLNCSE
SALRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPMDEAAALIAATI
HDVDHPGRTSSFLCNAGSELAILYNDIAVLESHHAALAFQLTMGDDKCNIFKNMERNDYR
TLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLAALEESEETKKNQEAINSMLRTPENRT
LIKRMLIKCADVSNPCRPLESCIEWAARISEEYFSQTDEEKQQDLPVVMPVFDRNTCSIP
KSQISFIDYFITDMFDAWDAFIELPDLMQHLDNNFKYWQGLDEMKLRGLRPPPE
>A0A085HG01|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Leminorella grimontii ATCC 33999 = DSM 5078|TrEMBL
MESLFQLPLASGSKVRVLQITDTHLFSGADETLLGVNTLQSFHAVLDEITGRECDYDLIV
ATGDLAQDRSFAAYQRFTDGISRLHAPCVWLPGNHDFQPAMVDAMAQAGILPSKLALLGE
DWFVILLDSQVLGVPHGELSEYQLEWLDRSLTQYASRHALILLHHHPLPSGCTWLDQHSL
RNAHVLSEVLDRHPQAKTLLCGHIHQDLSLDWNGRRVLATPSTCVQFKPHCTNFTIDDLA
PGWRYLDLYADGSVETTVCRLNSDVFRPDMNSDGY
>A0A2W1JFD4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acaryochloris thomasi RCC1774|TrEMBL
MPQPRSTRIAVIGDIHNHWNAQDHLALKSLNADLALFVGDFGNEAVEVVRQISTLDLPIA
TTFGNHDAWYTATPWGRKRCPYDRDKEDWVKQQMALLDHADTGYRHQDFDTVSVVGGRPF
SWGGPEWRFTDFYGEWFGVHNFEESAQRIQEAANAAAHDTLIFLGHNGPTGLGKEPEDTC
GKDWRPIGGDYGDPDLAAAIAAVKASGKSVPLVAFGHMHHSLRHTKEVQRTRLCIENGTV
YLNAACVPRIMDTEIGTQRNFSVVTLQENQVTEVNLVWVDEGLAIASTECLYTTMKVTEH
SASV
>A0A7U9T1X1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lachnospiraceae bacterium|TrEMBL
MPDWMETWPSVYAVGREYQICLPVRQECTMWVRVGEKDYCDHSNGILRSGKFLHIVHVPC
EALERERRYTVCLREIRKRRPYFTECGEVQSREYCFEPLVKKEEYHIINLADTHSLTKAP
VGSGSFFGEKLDLLVMNGDIPDDSGDPENFRAIYLISGAVSKGRVPCVFARGNHDMRGIY
AEQLADYTPTDGGKSYYTFRLGPVWGIVLDAGEDKEDGNPEYGHMVCCEAFREEEEDFLN
RVIAAGEYEQASVRLIVSHHPFVHCIKAPFDIEQERYARWSQKLKKLRPTVWLAGHLHEC
FLESPGGAHDTYGYPCPVVCSSDVDVPENRHIVGAVTITAEGIRVRYVSESGQVVGDETV
TVHGTGNRNN
>A0A7U9T0J3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lachnospiraceae bacterium|TrEMBL
MRYYIADPHFFHGNLNTKMDHRGFADVEEMNKHMLQRWNAKVRKNDEVVILGDLSWGKAE
ETNELLGKLNGRLYLIQGNHDRFLKNKDYNAGRFVWIKPYEEMQDNKRKVVLCHYPVMCY
NGQYRLDGNGNPKVYMLYGHVHDTYDQRLIEQFQKITRNSIRESPDGEMRAIPSNMINCF
CMYSDYTPLTLDEWILCDRKRRERLCADASM
>I3RS48|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. PSU3316|TrEMBL
MLSVRTADSFAAVVQEILNHQVQYEYILATGDISQDHSAESYQRFAEGIAPLKKDCFWLP
GNHDYKPNMGSVLPSPQIQAAEHVMLGEHWQLVLLDSQVVGVPHGRLSDQQLALLEEKLE
ENPQRHTLVLLHHHPLLVGSAWLDQHALKDADAFWQVVDRFENVKGILCGHVHQDMNVLY
NGIRVMATPSTCVQFKPDSDDFALDTESPGWRELELHSNGDITTEVNRLPDGQFQPDFNS
NGY
>A0A679IU91|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylobacterium bullatum|TrEMBL
MTAPASGRDDILAFAHIGDLHLTEAHLDNARDFLAIVAQLNAVEGLDFAYLPGDNADNGL
PYQYALVRQGLAGLSLPVHVVTGDHDLESGGLEAFYAGLGARRLPYAIDVSGIRCLFLDM
CGPGTGGPDFRLGDAQLVWLEGEIEMAERDGLDCALFMHSYPADLMGDGEASRVGHLVSN
SRVRLVEIGHTHYNELANDGRTIFAATRSTGQIEEGPVGYAIAAIDRGVVSWRFKELAEP
WPFVLVTAPADRRLAHDDGHRVRDTVEVRAIVLGASPVTACEVSVDGGPWQAMTRADGDR
RYRASIPWDAAACRLTVRASDAAGGTGRDVVEPATDGFRLPVSKGIGSDADSIGAWPEKG
LLGTQLGPNRNGRHW
>A0A6P3UIH9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bombus terrestris|TrEMBL
MDVLATTSRRLGWSVSVAKDAEKAVEFFQNRGHELVIIDHRGQRAAEADTICRAIRSSPA
YHNSIIIALVKKSFLMHGEKDKIVTLDLLETGFSRALMECSHERLLINELVGIYASALLP
RTQLAAANALYVALDRCRDMVHVTNDKHIVQFVNKISEKLLGYKTSEILGRSIADIVVYD
NFVLMEQHISKGREFEGNMNCKRKNNQMITISCRVIPFSISLKKPTHYIYIYDTTYLSEN
IGSLSPTPSQSVYSRGNMIVSQRRTSDMKSSEGRRRSSAHKLHSLQLDAPITKVISLLSN
AITESTTPDTTAQIEKAIDILKTTELYVPSLREDTDPVTTDLVGALLASPRKAWESRRSS
VESTRVSTTKGFTTTTASRMQIKGFRGPQEIAEILERCLEWNFDIFKLEILTEKRPLLFL
GTTIMNLYRVPARLGCEEKVVQNWLTVIEMNYQSRNSYHNSTHAADVLQATARFMQSERL
QQILEPLDEVATLVAAAAHDVDHPGRSSQFLCNSDNKLAILYNDLSVLESHHAALTFKLS
LSDDNVNIFKNLERDTYKQLRQTVIDMILATEMTKHFEHLAKFMNVCSARMMDSPQLDDY
SDTVDMSVVLQPENVVLVKRMMIKCADVSNPTRPLKCCVEWARRIAEEYFNQTDEEKRMQ
LPVLMPMFDRATCSIPKAQIGFVDFIINDMVEAWDAFIDMPEMVGYMRQNYEKWKEYNDR
GISTLPDIEKIQELPELRIYQLPS
>A0A6P3UII2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bombus terrestris|TrEMBL
MASPSNDSFFPNEGLNILDDILLSNGKTEYDVLRRRSSFEDIAVDDDENADCSALKGPQN
IEAHPLTNSVPSLIKILLVFPKDDQQMDVLATTSRRLGWSVSVAKDAEKAVEFFQNRGHE
LVIIDHRGQRAAEADTICRAIRSSPAYHNSIIIALVKKSFLMHGEKDKIVTLDLLETGFS
RALMECSHERLLINELVGIYASALLPRTQLAAANALYVALDRCRDMVHVTNDKHIVQFVN
KISEKLLGYKTSEILGRSIADIVVYDNFVLMEQHISKGREFEGNMNCKRKNNQMITISCR
VIPFSISLKKPTHYIYIYDTTYLSENIGSLSPTPSQSVYSRGNMIVSQRRTSDMKSSEGR
RRSSAHKLHSLQLDAPITKVISLLSNAITESTTPDTTAQIEKAIDILKTTELYVPSLRED
TDPVTTDLVGALLASPRKAWESRRSSVESTRVSTTKGFTTTTASRMQIKGFRGPQEIAEI
LERCLEWNFDIFKLEILTEKRPLLFLGTTIMNLYRVPARLGCEEKVVQNWLTVIEMNYQS
RNSYHNSTHAADVLQATARFMQSERLQQILEPLDEVATLVAAAAHDVDHPGRSSQFLCNS
DNKLAILYNDLSVLESHHAALTFKLSLSDDNVNIFKNLERDTYKQLRQTVIDMILATEMT
KHFEHLAKFMNVCSARMMDSPQLDDYSDTVDMSVVLQPENVVLVKRMMIKCADVSNPTRP
LKCCVEWARRIAEEYFNQTDEEKRMQLPVLMPMFDRATCSIPKAQIGFVDFIINDMVEAW
DAFIDMPEMVGYMRQNYEKWKEYNDRGISTLPDIEKIQELPELRIYQLPS
>Q8MLR1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila melanogaster|TrEMBL
MIRSASQGSTGTSGTSSSGGNSRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPP
NPPLKALLVFHKSDSICEAITAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIID
ARSSKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNL
AMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNM
RLDEIISKQLEDIFVSDLSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSA
PTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTS
LPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLI
GALLTGPSVYSSRRSSNDSIIRTGSSTRTAAIVPAKMKSNPIIMELLDESLSWDFDIFKL
EEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVM
QATGAFITQLTNKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLT
VLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSV
FGGEEPRDHNPQTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEK
QRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKY
DEQGVNTLAEIMAKQPPVGKMANSK
>A0A151I4C0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Atta colombica|TrEMBL
INLSQMKDQIPHRTVKNVEVSPRARRRAKIYKLLESIYLDKKELKGPQDLSNYLLTTNVP
SIVKILLVFSKDDQQMDILANTAKRLGWSVSVAKDAEKALELFQNRAHELVIIDHRTHHA
AEGDAICRAIRSSPVYHNSVIIALVKKSYFMLDEKDHIVALNLLETGFNRALMECSHEGI
LINELVGIYTSSLLPRTQLAAAHALYLALDRCRDMVHVTNDKNIVQFLNKVSEKLLGYQV
EEMMGRNLSEIVYYENYSVMEQQLKKGREFEGNMNCKRKNNQMITINCRIIPFCITLKKP
SHYIYVYDTTYLSENSAPISPISSPLHPPIKTSITNARKSSDVRSGSLSEDKGRRRSSLQ
KLHTLQLEAPITKVIMLLSIAVTDTINPETAAQIDKAIDILKTTELYIPHLKEDRAICCD
PVATDLVGALLASPRTAWESRRSSSDSAKLSTIKAITSPVNSRMQVKNFRGPQEIMEILD
RSLDWDFDIFKLEVLTEKRPLVFLGLTIMNLYQVSTILQCDERILQNWLAIIEHNYNAEN
SYHNSTHAADVLQATARFMQSKRLKEILEPLDEVAGLIAAAAHDIDHPGRSSQFLCNANN
RLAILYNDLSVLESHHAALTFKLSLSDDSVNIFKNMDRDAYKLLRQNVIDMILATEMTKH
FEHLAKFMNVCSARIGDGQETYSDSVDMSVVLQPENIMLVKRMMIKCADVSNPTRPLKCC
VEWARRIAEEYFNQTDEEKKLKMPVVMPMFDRMTCSIPKSQIGFVDYIINDMIEAWDVFI
DMPEIVGYMRQNYEKWKEYNEQGISTLQDLEKLQQLPEMQILS
>A0A1V3JPC4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rodentibacter genomosp. 2|TrEMBL
MKNTFVYRTEKPMVKLLQITDPHLFKDEKNELLGVNTQASFAQVLKEIQQENTEFDAILA
TGDLVQDSSDEGYQRFVNMVKPFGLPVFWIPGNHDFQPKMVENLNQPPMEKAKHILLGEY
WQVLLLDSQVYGVPHGELSQYQLDLLKTTLEKYPEHHTLIVFHHHVLPTNSAWLDQHNLR
NSHDLFDVLSPFKNVKGILYGHIHQQVDSSWQGYQVMATPSTCIQFKADSQHFALDEVQP
GWREIELHSDGTIVTTVKRIRQARFLPNMQEEGY
>C6CMC8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dickeya chrysanthemi (strain Ech1591)|TrEMBL
MESLLTLPVARGARIRILQITDTHLFAAEQGTLLGVNTYRSYQAVLAAIAAQQLDVDLIT
ATGDLAQDHTQDAYTHFAHGIRRFNAPCVWLPGNHDFQPAMVDVLARSGIVPSKHVLLGD
HWQVILLDSQVFGVPHGELSEYQLEWLERSLLSQPARHTLLMLHHHPLPSGCTWLDQHSL
RNAHSLDALLARFPQVRTVLCGHIHQEMDLDWNGRRLLATPSTCVQFKPHCTNFTIDNVA
PGWRYLELLPDGEVETQVCRLDGNEFLPDMDSDGY
>A0A6I8VRZ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila pseudoobscura pseudoobscura|TrEMBL
MRNCLPKLTNVFRRKSSAKSSATGNRANHSNDCLSDSDSEQYTAVAMSGGALAIPSPQSD
QPHDNNNKRPPHTDGDSSYSRLISGSHLETVAVAPNVRIRTMDESSFTEMRVEAISGQAP
GPTSGPTPGPARLSVPIPGRNSISLPFAGLGSSKTPEEMELEYEANVKAEGGDIVTPLRR
NTNTTGTRPHSMALNGGRSASLQPEIVEAIRNLDVQGLFFNNLAMEDRDSESDSQCHEDA
VVLRRKVAGLERKSCSLYERRMPKMPKLHLMVAGKKPQPQQQPEDDDDEYKVFQRNLMDL
KYPTVLPPNPQLKALLVFHKSDSICEAVASACQRHQLDVTLVKSKEEALDTLQKSYATAQ
CYHLIIIDARSSKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNR
CVAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANR
ATERLLNMRLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMHVRVV
PVACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRR
TSLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTD
DPIATDLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKANPIIMELLEESLS
WDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIEENVCKAWLAVIEAHYHKSNTYHN
STHAADVMQATGAFITQLTNKDMMVMDRMEEAMALIAAAAHDIDHPGRSSAFLCNSNSAL
AILYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFE
HLAKFVSVFGGEEPREHNPQSDEETAILMRRMLIKVADVSNPARPMQFCIEWARRIAEEY
FMQTDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQI
NYSQWKKYDEQGVNTLADVMAMQPPMVKLANSK
>A0A3Q0RVY4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Amphilophus citrinellus|TrEMBL
MTVKGKIRLAGCWRKGSRFFDVENGLSVGRSPLDSQTSPGSGLVLQANFPHSQRRESFLY
RSDSDFDLSPKTMSRNSSTASDLHGEDMIVTPFAQVLASLRTVRSNFAVLTHLQDRVGNK
RPSSSNQPSMCNPCLTGQY
>A0A060XKW2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Oncorhynchus mykiss|TrEMBL
MDSQASPVLGLHPSFTTEGCRSRGERRESFLYRSDSDYDMSPKTMSRNSSINSEGHAEDL
IVTPFAQVLASLRTVRSNFTILANVTTPTNKRSPVTSQPTVPQATLSDETYQQMARETLA
ELDWCLDQLETIQTHRSVGDMASNKVLPLLPPPLPYTITTTTTTCTLHNRYPYPTQSLPP
PLPISYTTTTTTTILHYHYHYHYPTLPLHPPHTTLHHHNHDHYHYI
>A0A3N6NNS1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Okeania hirsuta|TrEMBL
MIFQPSVLVAQITDTHLFADSIQGKMYGVPTERSFVKVLEKLKQLQPQPDVLLLTGDLSQ
DETSQSYQRLASLLSPLNIPTYWIAGNHDNLPTMERVLSSAPISAKKSFEMGGWNFFLLN
TNVPGCVYGEISPESLEWLEYNIKMTGNKPVLIALHHPPVKINSEWMDKILLHNPENFLS
IINRYPQVKIVLSGHIHQEFAKEINGIHYLSTPSTCIQFEPGNYKFFLDKQPPGLRLLTL
YPDGNYTTKIERINYIYECDMAASGY
>A0A287DEA2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ictidomys tridecemlineatus|TrEMBL
LPAVAVDAPSFQMAFVWDPLGATVPGPSPRAKSRFHFSKSYSFDVDNGTSAGRSPLDPMT
SPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVL
ASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLKELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFR
IAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADV
VQSTHVLLSTPALEAVFTDLEILAAIFASAIQDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKXXKKNVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRER
ERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQS
TIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVGEEESQPEAPVIDDCSPDT
>A0A2S6U3W3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alphaproteobacteria bacterium MarineAlpha4_Bin1|TrEMBL
MTRLLHFTDMHLRWHQPGSAANPKRASRDMPGALDRLAANIAALAPDILIMSGDILDMPD
PVIAGGSPDGRPHDAWMADAIADFQLVKDWFEATGIPYIAVPGNHDHEGAFAAVFGGPPE
PRDIAGLRFFSFWDRLAADRQPHRTGARRAMFARALDAPEHDCAQIHIQHYMIDPPTFAK
GWHYQYKGAAAMKRDIARSGRVRAVLSGHYHPGSLVADDAVVHSLPPAFCEAPHAFRIYD
IDKNGVDVTDQALDR
>A0A2J9QJU4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pasteurella multocida|TrEMBL
MFSTYKYDTSAEVFKIIQITDPHLFKDEHGELLGINTFQSFSQVLQEIKASRFDYDLVLA
TGDIVQDSSREGYLHFCEQVKSLEKTVFWIPGNHDFQPKMFEILNQDQGNLNPKKHILLG
NSWQILMLDSQVFGVPHGELSQYQIDWLVAKLKDYPERYTLIVLHHHILPTHSTWLDQHN
LRNAHELSYALAPFDKVKGILHGHIHQEMDANWQGYRVMATPATCIQFKPDHNTFTLDSV
QPGWRELELYSDGRIETRVKRIQYKTFVPNMHEDGY
>A0A8C9TL48|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Scleropages formosus|TrEMBL
MLPSCDLTEEAYQQLAHETLEELDWCLDQSETIETHRSVSDVASTKVQISPVLTDTRTAA
PTTTM
>A0A8C9V6B5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Scleropages formosus|TrEMBL
AANGSRGGFDVENGPSTSCSPLNPQTPPSSGLVLHTNFPGHTQRRKSFLYQSDSDYDLSP
KSMSRNSSIISELHGDNLIVTPFSQVPASLRSVRKNFSVLTNIQCASNRWSPVANQPPIT
RVCLSEELYQKLAMDTMEELDWCLDQLETIQMYRSVSKMASNKFKRMLNRELTHLSEMSR
SGNQVSEFISNTFLDKQNDVEIPSPTSKTREKKNSR
>A0A7L6IBS0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. RHBSTW-00570|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRAKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A1V9DGP5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea latae|TrEMBL
MDSLLTLPAANGAGIRILQITDTHLFAGKNESLLGVNTWASYDAVLDAIAAQQRDFDLII
ATGDLAQDHSVEAYQHFAEGIARLPKPCVWLPGNHDFQPAMVDTLAEAAIAAQKHVLLGE
HWQLVMLDSQVFGVPHGMLSDYQLEWLEKALARFPQRHTLVVLHHHPLASGCTWLDQHSL
RNAHQLDAVLQHYPLARTLVCGHIHQELDLSWHDRRVLATPSTCVQFKPHCTSFTIDTVA
PGWRWFTLHPDGSFDTEVERLQTDAFRPDLDSDGY
>A0A6I4VE45|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. Eser|TrEMBL
MDSLLTLPAANGSAIRILQITDTHLFAGKHESLLGVNTWSSYEAVLDAIIAQHRDYDLII
ATGDLAQDHSVEAYQHFAEGISRSPRPCVWLPGNHDFQPAMVDTLADAQINPHKQVLIGE
QWQIVLLDSQVFGVPHGMLSDYQLEWLENALARYPQRHTLVLLHHHPLASGCTWLDQHRL
RNSHQLDAVLQQFPLAKTLVCGHIHQELDVEWHGRRVLATPSTCVQFKPHCTSFAIDTVA
PGWRWFTLHPDGQLETEVNRLDTDIFRPDLDFEGY
>A0A4P6WE60|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter sp. JH2|TrEMBL
MTHSDPKHPLRVLQLTDPHLTAQSDGALLGVNTRDSLAAVIEDVLKEHGQPDLVLATGDI
SQDASVEAYRYFGEQLEAFECPSLWIAGNHDDTSLMNSIAAEFRADQSEWMQGGWHFVML
DSSVHGKVFGELSGEELAHLDNALSEQPELPTMVCLHHHPVDIGSDWMEKIGLKTREAFW
RIIDKHPQVKVVLWGHIHQELHRQRNGVQLLATPSTCIQFTAGASNFSVEPRAPGYRWIE
LNPSGNIYTEVRRATQFEFELDENSSGY
>A0A821Q3H4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ranitomeya imitator|TrEMBL
MTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQ
VLASLRTVRNNFAALTNLQDRASSKRSAMCNQPSINKASISGKADHLVVTEVFLPEMPGN
CD
>A0A328W2M5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. MDMC224|TrEMBL
MPSLPTQSTDSSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIERVLQEQPQIDLILAT
GDLSQDGSEASYQRFRQLTSAIDAPTRWLAGNHDEIPPMQAACQGSELLEPVIDLGAWRI
VMLDSSIPGAVPGFLADSQLELLERALSEAPQRHHLICLHHHPVSIGCKWMEPIGLRNPD
ALFAVLDRYPQARTVLWGHIHQEFDQQRGNLRLLASPSTCVQFAPGSEEFQVDSEAPGYR
WLRLHADGRLDTGVSRVTGIHFEVDYSVKGY
>A0A701U5D5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae serovar 47:b:1,5|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLVLQANGVLETEVHRLQDTRFRPDTASEGY
>A0A822EHE9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ranitomeya imitator|TrEMBL
MSPKTMSRNSSVTSEAHTEDLIVTPFAQVLASLRSVRNNFTILANVTTPTNKRSPVLPQQ
TVCKATLSEETYQQLAKETLEELDWCLDQLETIQTYRSVSEMASNKVRDWSTHTHLLPS
>A0A554AC07|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. ef1|TrEMBL
MPSVSTLTSADPALLVQLSDSHLFAEADGTLLGMKTRESLQRVIDLVLAQQAQIDLVLAT
GDISQDGTLQSYQAFRQLSAQISAPARWIPGNHDEPMVMAEAAVQSTLLEPVVDIGNWRV
TMLDSAVPGSVPGYLQDDQLQLLARALSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQVRAVLWGHVHQQIDRERNGVRLMASPSTCIQFEPGSADFKVGEQAPGYR
WLRLLPDGQLETGVERVTDFEFTVDYGSNGY
>A0A6B9SSY0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio phage VH1_2019|TrEMBL
MANLKVYYCSDIHNDYHDENALERITGDKDAVLVVAGDINSKGRTVRDLEAVADRWRAVI
AVPGNHDWWGLAIHERHKFETSVDNVHVLLEDTVQIDDVTFCGTTLWHEVNDWFEGQRWK
ENMNDRRKIRGPQWRPLYGEDVHALHCQSVKFIEKCREIEGKKVLITHHAPSLKSISSYY
AYSSTNSFYCTDLEHLLEGFNFAIHGHVHQEFDYHVNGCNVLCNPRAYGSENPDYGLRIF
DI
>A0A2S5KBJ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. ICBG 1758|TrEMBL
MDSLLTFPAAPGSAIRILQITDTHLFAGKHQSLLGVNTWASFDAVLDAIAAQQHEYDLII
ATGDLAQDHTVEAYQHFVAGIARLQKPCVWLPGNHDFQPAMVNTLAEAGIAADKHVLLGE
QWQLLLLDSQVSGVPHGMLSDYQLEWLAASLARFPGRHSLILLHHHPVPSGCTWLDQHSL
RNPHQLEAVLQAFPQAQHLVCGHIHQELDLHWQGRRVLASPSTCVQFKPHCTSFTIDTLA
PGWRWLTLAADGSLETEVNRLQSDMFRPDLDSDGY
>A0A558H0E7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio atlanticus|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVNQGFDYEAILA
TGDISQDHSAESYQKFESGIQPLERPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEKKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSNDFAVDTLSP
GWREIELHQDGTVTTEVRRLPHGQFLPDFTAGGY
>A0A2D0L8U3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Xenorhabdus kozodoii|TrEMBL
MESLLEVPVAEGAAARILQITDTHLFANKGDSLLGVNTYCSYHAVLDMILAQNLDIDLIV
ATGDLVQDQTINAYQHFAQGIARLSAPCVWLPGNHDYQPAMVDTLAAAGISPSKQIFIGQ
RWQLIMLDSQVQGVPHGELTDYQLEWMKKCLDEHCDRHAIIMLHHHPVPSGCTWLDQHSL
RNAPDLSECLKGRTQVKAILCGHIHQEVDEMWNGIRVMATPSTCVQFKPHCTNFMLDTVA
PGWRYLELSVAGNHKEAKLQTQVHRLKSNEFCPDLDSDGY
>A0A6B0VEX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ixodes ricinus|TrEMBL
MGCTQSGIQRRSRSHDDRSQGPATPVVCDVAPPTANATTMTAPGSLTTTAAPKGGCGAGV
LRGNAHRFENNFPKVRQKVVTCDGVNDCAVPLCSIPEDGRKGTVALKFGSMYLTVPSVRV
LFVFVKEDAQYNALKWASEKMHYEYRLACSMDEAVESYLNVQPHLVFIDARSKTCVDPIA
LCRTLRGFRGSQFSCIVAVVKKGLAEKEEAAIIPLLKSGFNRWFTETCSFGVCLNEMIQI
EHNDLINLWKLRASEALFSALHIARDGVIITGSGHEIQFMNRAAEKLVGYSVEEMLGVNA
QELHRTDSLKTDVVQTISTQLKKGKEWEGTLFHKRKSGECIPMWSKIAPVEIHTGISDHL
VYIKECPFFMEKPFSPDAVGMNRRQSFAKFHAMTIEAPITKVINMLVATQENSPVFVVQA
LDRVLEILRSTELYNPQLGVGQGKSEDQMTSDLVSGLITTGQKPTGVRRLSHETGVVKVN
VTTPSTTLPSLSTAPSKIKDLLENDVKWEFDIIELETLSGRRPLIWLGLSLFSKLNVHTS
LDCDDATIRNWLQLVESHYLENPYHNSTHAGDVMQATAYFLLKLRKKDIFDPLDEAICLI
SAVVHDIDHPGKSSPFLCNSDNELAILYNDRSVLESHHAAFAFKLTLSDEKVNIFQNLER
EVYRTVRLSVIDMVLATEMTKHFEHLSKFLNAFQKPIQEDEAFESEAMPDHGDSGLRSAE
NIILIKRMLIKCSDVSNPARPIQLCSQWASRIAEEYCAQTDEEKRRGLPVVMPAFDRATC
SIANSQTGFINYFVRDMFRAWSDFGEFPELMEYIEKNYIYWKDKEPQSNK
>A0A147BSQ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ixodes ricinus|TrEMBL
LNEMIQIEHNDLINLWKLRASEALFSALHIARDGVIITGSGHEIQFMNRAAEKLVGYSVE
EMLGVNAQELHRTDSLKTDVVQTISTQLKKGKEWEGTLFHKRKSGECIPMWSKIAPVEIH
TGISDHLVYIKECPFFMEKPFSPDAVGMNRRQSFAKFHAMTIEAPITKVINMLVATQENS
PVFVVQALDRVLEILRSTELYNPQLGVGQGKSEDQMTSDLVSGLITTGQKPTGVRRLSHE
TGVVKVNVTTPSTTLPSLSTAPSKIKDLLEGDVKWEFDIIELETLSGRRPLIWLGLSLFS
KLNVHTSLDCDDATIRNWLQLVESHYLENPYHNSTHAGDVMQATAYFLLKLRKKDIFDPL
DEAICLISAVVHDIDHPGKSSPFLCNSDNELAILYNDRSVLESHHAAFAFKLTLSDEKVN
IFQNLEREVYRTVRLSVIDMVLATEMTKHFEHLSKFLNAFQKPIQEDEAFESEAMPDHGD
SGLRSAENIILIKRMLIKCSDVSNPARPIQLCSQWASRIAEEYCAQTDEEKRRGLPVVMP
AFDRATCSIANSQTGFINYFVRDMFRAW
>A0A2H5V428|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|archaeon HR02|TrEMBL
MKILQVSDIHGSSRSAVMIGSKAKDVGADIVLVVGDITNFGSVEGAEKILSTIVELAHVP
ILFVPGNCDPPQLLSYSPRSQNLVNIHAKKIQISGYTFVGVGGSKTTPHRGTWIEFSEEE
LGEILAGLVGGDGLIDWVFVSHNPPIGVEVSMAGSGVDLGSTSIRRFIESYKPIVVCCGH
VHEARGISYLGETPVVNAGPAKEGYCTLIELHERHAHVYLDTL
>A0A6G8NRB6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Caballeronia sp. SBC1|TrEMBL
MLLAQITDLHIKLPGVLAYRKVDTAACLRACVERLNALSPRPDAVLVTGDLVDFGTADEY
RHLAACLKPLEMPVYLMVGNHDDRAALREVFDAPYLHESGTGSDFVQYAFDLQDMRVIAL
DSQKPQESPGTLCDARLAWLEHQLEAADGRPVIVALHHPPFATGIGHMDDMALDAQAASK
LEALISRYPNVERVLCGHVHRPVHKRFAGTIASIAPSTAHQVVLDLHADAPSAFVLEPGA
FALHYWTAGVGLVSHHEYVEQFDGPYPFFDDDGALVD
>A0A8D4R752|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNVAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLIVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELYSDGSIRTEVKRIQQAEFLPNMQEEGY
>A0A1V0RKL4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Roseovarius mucosus|TrEMBL
MHKILVFTDVHIVAQGQTIIGLDPFARFTQGLAHALTRHPDAARIVLCGDLTHRAAPEEY
ARLREALADCPLPVSLMLGNHDRRAAFLTAFPETTQMDSGHIQHTADIGAYRLICLDTLD
EAAPDLHSGWLCPARLDWLDQRLNEAGPRPVIVFTHHPPIDTGFAGMDAIGLRNRDELIA
RLSAADNVVQIMSGHIHRTVQGSAGGIPTAILKSPCHQMPMSLDAQDTSLSIDEPGAYGL
LLLTETGVIVHTEDFTLPATLSATYS
>A0A663BEW5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella quasipneumoniae subsp. similipneumoniae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QMARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDAQNMRYAVDDFATRLLFID
SSRAGTSKGWLTDETIGWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A380QD01|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Yersinia pseudotuberculosis|TrEMBL
MALPTDSHNTNNYLVGGRQKQGYHLESLFKLPMASGARVRVLQITDTHLFAGEHETLLGV
NTSHSYRAVLDAIIAEQHPFDLVVATGDLAQDHSVAAYQNFAKGISRLPVPCVWLPGNHD
FQPAMVDALAEAGIAPSKQVLAGEHWQILLLDSQVFGVPYGELSDYQLEWMERCLIAYPE
RYTLILLHHHPMPSGCTWLDQHSLRNAHMLAAILTRYPRVTTLLCGHIHQDLDLDWYGKR
LLASPSTCVQFKPHCTNFTLDAVAPGWRYLDLLPDGGLETEVHRLDSDEFCPDMDSDGY
>A0A7G7ET66|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas jandaei|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLERVQANNHPYEVILAT
GDLSQDHSPESYQRFASMMAPLGRPIYWLPGNHDDSPLMTEQLHAAGISESKQLVGDHWQ
VILLDTQVRGKPHGMIGDHQLEALDRALRQYPDRHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRIASQVWRLPVGQFVPDPNATGY
>A0A6P8PRZ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Geotrypetes seraphini|TrEMBL
MAQPTASSDTLTVPEVDNSHGPNPWLNEDLVKTLRENLLQHEKSKASRKSPIVSPRLSPI
ISPRNSPRLLRRMLLNSNIPKQRRFTVAHTCFDVDNGTSSGRSPLDPMTSPGSGLILQAN
FVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFA
AITNLQDRAPSKRSPMCNQPPINKATIPDARIIHT
>A0A853G7S9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alcaligenaceae bacterium|TrEMBL
MTSHLDYDVPVTIVQLTDPHLFSDPDARLLNVATDASLRAVLQDIAVHYPSPDLLLATGD
IAQDGSLAAYQRFLQLTAIVDAPLRSLPGNHDARDNFHAVLQDKAQPVIDIGNWRVILLD
TLIPGSNGGELLPDQLTLLKTAAQQAGKKHILVTLHHNPVAVGCEWLDPMMISNGQQLLD
VIEDFPQVHALLWGHVHQEYDAMHQYAQAGHNLRLLATPSTCIQFTPNSSQFSLDTTGPG
YRWLTLHPDGQLDTGVRYIPGQDFQPDPLSGGY
>A0A231MVC3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Zobellella denitrificans|TrEMBL
MLPLPRIQHGQTALNRATTQPAPTRLQPRRADGVIELLQITDTHLFAGADTDLLGIAPWR
SCRAVVDAILEDDSPRDLILATGDLSQDHSPESYRHFTRLMGELAPPVFWLPGNHDDAPV
MQAELDAAGISNAKQLLCGNWQILLLDTQLRGAVHGELAPEQLALLEQAIDDYPHHHLLV
AVHHQAVPVGCAWLDQHNLRNAGELKQRLARHRAAKVVLFGHVHQGFDEVHDGVRYLASP
STCIQFKPLSDDFALDHTAPGWRALTLYPDGRLSTQVWRLPPDAFVPDFSATGY
>A0A4Z2EFX5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Liparis tanakae|TrEMBL
MLNRELTQLSETSRSGNQVSEFIANTFLGERWLRPLCLRANTTRSLHSHELIPLVLMDQL
VYTLDNSLDVYGVKHNE
>A0A3M0K6L0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hirundo rustica rustica|TrEMBL
MEELFQGLANVPGHLLCPGSAQEKSRCPSVRVPDREQGSFDVENGPSPGRSPLDPQASSS
SGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTLLTNLHGTSNKRSPATSQPPVTRVNLQELRILINFVFASSASGQVELFSSE
LQFLLLSQALIQLGLSKVVSQLLAAYSMSSVSIPILSCMG
>A0A0S7GZK1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
KVTLQNSPFASFTRLSCPVQRHWDSSEPASSVELLQDPDVRYAVKRVFSGNVQLPRLSCR
PSAQERAQDGAPPEPAAPPTRSIRHSRSLGTLTSCFDVENGLSVPRNPLDAQSSSSSGLV
LQVNYPHSQRRESFLYRSDSDFDLSPKGPSRNLSSTSDLHSEDMIVTPFAQVLASLRTVR
SNFALITGQQDRAASKTRSSGSNPPSMCKTSLAEEPHQQLAIETLDELDWCLDQLDTLKT
RNSVSEMASNKFKRMLNRELSQLSETSRSGNQVSEFISSTFLEKPDDMDIMSPTTKEKDK
KKHPMSQISGVKKATHSLVPSTIPRFGVNVSQEEFLAKELEDIDRWGLDIFKVAEYSGKR
PLTVTMYTIFQERDLLKTFKIPADHFINFTMTLEDHYRSDVAYHNNIHAADVVQSTHVLL
STPALEAVFTDLENHHLAVGFKLLQEDNCDILQNLSKKQRQSLRKMVIDMVLATDMSKHM
NLLADLKTMVETKKVTNLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIM
VEFFTQGDREREKGMEISPMCD
>A0A659LCC3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. E2661|TrEMBL
MESLLTLPLAGESRVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADSRFQPDTASEGY
>A0A5W5K4F8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella ordonez|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A8B9MVJ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Accipiter nisus|TrEMBL
MCVCIVLYFSFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEIEIPSPTQKEKEKK
KRPMSQISGVKKLMHSSSLTNSSIPRFGVKTDQEDVLAKELEDVDKWGLQVFRVAELSGN
RPLTVIMHAIFQEWDLLKTFKIPVDTLITYLMTLEDHYHSDVAYHNNIHAADVVQSTHVL
LSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLA
VGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSS
GVLLLDNYSDRIQVLQNMVHCADLSNPTKPLHLYRQWTDRIMEEFFHQGDWERERGMEIS
PMCDKHNASVEKSQVIDLSRHLNKTV
>A8H8I6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)|TrEMBL
MLKAAISYSISEVESVRIVQVTDPHLFADPEAQLLGVNTANSLGAVLNTISAVNYPAHLM
LATGDISQDYSNESYHSFVKAIEPVNLPCHYLPGNHDDPRIMNLHMQGPKIFAQKRILAG
NWQIIMLDSTVRERPGGHMSEAELELIDSSIKAEPGRNVLLVMHHNPVLTGCNWLDQHCM
DNGASFIERVAQYPQVKGLLWGHVHQSIDTKHMGPHGALHLMATPSTCIQFKPKSPYFAL
DALQPGYRLLELKSDGSILTNVYRVPGETFSPDKDAGGY
>A0A5N3QVY2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio fortis|TrEMBL
MELSHTSKLDESSIKLVQLTDTHLFAPSNGSLLSINTEDSFRAVVDGIVNQGYEYEAVLA
TGDISQDHSAESYQKFETGIQPLEKPCYWLPGNHDYKPNMGSVIPSAQIQCVEHVLLGEH
WQMILLDSQVVGVPHGRLSDQQLELLEQKLAEHPQKHTLVLLHHHPLLVGSAWLDQHCLK
DADQFWDVVSQHNNVRGVLCGHVHQDMNREHLGVQVMATPSTCVQFKPNSDDFALDTLSP
GWRELELKPNGEITTEVRRLERGAFAPDFNAEGY
>A0A2R7Q4D2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sp. HMWF015|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQANEHPYEVILAT
GDLSQDHSPESYQRFASMMAPLGRPIYWLPGNHDDSPLMTEYLHAAGISESKQLVGDHWQ
VILLDTQVRGKPHGMIGDHQLAALDRALRQYPDRHALITLHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEEHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRVASEVWRLPVGQFVPDPNATGY
>A0A6C8GCQ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Infantis str. SARB27|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A7A6V698|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLHHHPLPAGCSWLDQHSLR
NAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAP
GWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A3D5MCH7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwiniaceae bacterium|TrEMBL
MDSLLKLPVVSGASIRILQITDTHLFSGRHETLLGVNTWASFNAVLDAIEAERQPIDLVI
ATGDLAQDHTPEAYQHFAEGIARLPAPCVWLPGNHDFQPTMYGALAQSGIAEAKQVFVGE
RWQLLLLDSQVAGVPHGMLSDYQLDWLEKTLAQTADRHTLILLHHHPLPSGCSWLDQHSL
RNPHALEAILQPYPLAKTLICGHIHQEMDVDWHGRRLLATPSTCVQFKPHCTNFTIDAVA
PGWRWLELDEDGAVRTRVQRLASRAFTPDLDSEGY
>A0A8H0AHL3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQYSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>A0A3A8ED38|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter guerrae|TrEMBL
MSFQVVPSSTQEYVLIQITDTHLLEQPEQEFVGMNPEQSFHQVMAHIQKHYPHVDAIIHT
GDLAQAPKPKTYQRYLQFMQQFGIPFFHTPGNHDDEKYFPFHGEHPQQPILIELGNWRII
LLNSAVSNRVDGFISTQQLEQLTNLLEQHQAYPTILACHHHPFEMHSKWIDQHKLKNSQA
IFDLLERFKQVKAILYGHVHQNSSNFWQHIECLSSPSTSVQFKPCSDQFALDVLTPGYRV
LKLKINGEFETQVQRLEQINYSINTEISGY
>A0A5B8NNU5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Euhalothece natronophila Z-M001|TrEMBL
MRKASPLLIAQITDTHLFASSQEELLGLQTDSSFKAVLREIQALTPQPQGLLLTGDLSQD
ETLASYQNLYQQLEPLQIPAYWLPGNHDQPQLMQEALTKPPTYGDKSFQLGSWQFILLNS
AVPGRVYGYLSSETLEWLDKQLYNNSHAPTLVALHHPPFSVNSHWIDTSRLKNPEDLFRV
LDCHPQVNLVVFGHIHQNFQRDRAGVRYLASPSSSIQFKPECDRFALDELQPGYRLFWLY
ENGEFATTVKRVEFSYTVDLAATGY
>A0A6P7U9G9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ixodes scapularis|TrEMBL
MYLTVPSVRVLFVFVKEDAQYNALKWASDKMHYEYRLACSMDEAVESYLNVQPHLVFIDA
RSKTCVDPIALCRTLRGFRGSQFSCIVAVVKKGLAEKEEAAIIPLLKSGFNRWFTETCSF
GVCLNEMIQIEHNDLINLWKLRASEALFSALHIARDGVIITGSGHEIQFMNRAAEKLVGY
SVEEMLGVNAQELHRTDSLKTDVVQTISTQLKKGKEWEGTLFHKRKSGECIPMWSKIAPV
EIHTGISDHLVYIKECPFFMEKPFSPDAVGMNRRQSFAKFHAMTIEAPITKVINMLVATQ
ENSPVFVVQALDRVLEILRSTELYNPQLGVGQGKSEDQMTSDLVSGLITTGQKPTGVRRL
SHETGVVKVNVTTPSTTLPSLSTAPSKIKDLLESDVKWEFDIIELETLSGRRPLIWLGLS
LFSKLNVHTSLDCDDATIRNWLQLVESHYLENPYHNSTHAGDVMQATAYFLLKLRKKDIF
DPLDEAICLISAVVHDIDHPGKSSPFLCNSDNELAILYNDRSVLESHHAAFAFKLTLSDE
KVNIFQNLEREVYRTVRLSVIDMVLATEMTKHFEHLSKFLNAFQKPIQEDEAFESETDEE
KRRGLPVVMPAFDRATCSIANSQTGFINYFVRDMFRAWSDFGEFPELMEYIEKNYIYWKD
KEPQSNK
>A0A5D4YH42|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lelliottia nimipressuralis|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHLENRDCDLIV
ATGDLAQDQSAAAYQHFATGIASFSVPCVWLPGNHDFQPAMYSALQDAGISPAKRVFVGD
HWQILLLDTQVFGVPHGELSDFQLEWLESKLIDAPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLSKYPHVNNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGRLTTEVCRLEGAQFRPDTASEGY
>A0A667XF29|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Myripristis murdjan|TrEMBL
RFHGDKLFIFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSP
KSMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNLQDRTSNKRSPMCNPPPI
TKTSFTGMWAA
>A0A1Z5JTI6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Fistulifera solaris|TrEMBL
MSSTAPPYAATALALSVKHWKDLGIDDGDEETAPTNDLNTLVERLTAILVVRCVAIVAEK
DEFNDLSTATICRSTLMRQASWPEPITADVVEQIRTFVHAILSRYNDNPYHNREHAYHVT
TSAHKLLELMLLEKQQTFGLRNDPLMQFALIFAALIHDVEHQGLPNRQLCNEAAKLAVTY
NDQSVAENRSLAIGFHELLKQDYKELRAVLFGNSDETDPSQSDYQRFRRQVISLVLTTDI
ANPERTALFKSKWVEAFESPLVDDDVSVLEDDDEKKDLKEGENEEDASESRDVVTSDKVG
ERRRSNASTGSFRSRGSSRGGTRLGVRMSIDLSGEALHIYKQVGNSKNSEEPDELKISVL
LELFLTAADVSHNLQGWEQMVKWSNCLYLELQRALLMGRGTDPKPNWFQNQIGFLEFYLL
PLANKLNETGVFGGFVGKQFATTVLANRDRWVKKGQKVTDQIIEEGKKMLNDNATICNPC
RMDDEADRDLDLENGEMEASNDPGEGGSPTDWVKVFMFVVIVLLLGVILQLSQIRRHPKT
PPKGYPGVWKINCRKLGKAIAPVDLCKDGYLRIDSGGHATFHNRVSDDCDESEMNICFRN
APILTQQHLIKIGLSTLPSEEENVAVA
>A0A226NHE2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Callipepla squamata|TrEMBL
MLNVNAACSRRHSWICFDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRS
DSDYDLSPKTMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTANKRSP
ATSQPPVSRVNLQELLLDEEKSRHDFPAPLSCSCYSDGA
>A0A226MXQ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Callipepla squamata|TrEMBL
MQCFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRN
SSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATIT
ANSRNEDWIVWKLRTEKKRGEERRGEERRGEERRGEERREEKRREEKRREEKRREEKRRE
EKRREEKRREEKRREEKRREEEREERRGERREEKEEKRMIVKLYTSDHLIQDGF
>A0A7Y7VTQ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. D2002|TrEMBL
MPSVSTVNPDASALLVQLSDSHLFAEADGALLGMNTRESLQRVIALVREQQPQIDLVLAT
GDLSQDGTLESYQQFRELTRQIDAPARWIPGNHDEPQIMAHAAEHSDLLESVVDIGNWRV
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPSRHHLVCFHHHPVPIGCAWMEPIGLRNPD
ALFAVLDRFPQVKAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERVEGFAFTVDYGSNGY
>A0A5D3I589|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moorella thermoacetica|TrEMBL
MLRILYLTDTHLRGTAPASRTDDFAAAVKAKLAEVVGLAESLNAAAVVHGGDLFDLPEPG
VGQVGEYLEILSKLHVPLFVVPGNHDIYGHNPSTLPRTLLGLLARVGVVRILDREPAIIE
GGGVRFRLTGQGFHSEMDRRGPAEDYAVPPAARDNCDYAVHIVHGMLLPRAEISSAPFLP
AATAAEDVLTVTGADYTLAGHYHSPWEMHVGGRVAANPGALVRVTSEARELARRPQVMVI
EACRDGIRHRYIPLSSARPGEEVLDAARLDADRAREEARAEFLASLEAFGGGPHGVDPEE
VLRETMNRMGVGPEVEAEVWWRFQEARV
>A0A097QXY0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hafnia alvei FB1|TrEMBL
MESLFQLTVARGAPVRILQITDTHLFAGEHETLLGVNTYRSYHAVLEAIHAQSRPYDIVV
ATGDLAQDHSVAAYQHFAKGIATLNKTCLWLPGNHDFQPAMVDTLADAGVSPAKHMLLGD
HWQIILLDSQVFGVPHGELSEYQLEWLDRTLSLYPARHSLILLHHHPLPSGCTWLDQHSL
RNAHMLGEILQHHPLAKTLLCGHIHQDLDLEWQGRRLLATPSTCIQFKPLCTNFTIDTLS
PGWRYLDLHPDGTLTTELHRLEGTEFRPDLDSDGY
>A0A6I0CD36|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. GXM4|TrEMBL
MPSVSTLTSADPALLVQLSDSHLFAEADGTLLGMKTRESLQRVIDLVLAQQAQIDLLLAT
GDISQDGTLQSYQAFRQLSAQINAPARWIPGNHDEPMVMAEAAVQSTLLESVVDIGNWRV
TMLDSAVPGSVPGYLQDDQLQLLARALSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQVRAVLWGHVHQEIDRERNGVRLMASPSTCIQFEPGSADFKVGEQAPGYR
WLRLLPDGKLETGVERVTDFEFTVDYGSNGY
>A0A5B9TWB7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sulfurospirillum multivorans|TrEMBL
MFRLSFAFAAIAVLSLINFYSYKRFLKRLDIFCKIQGVIKWLMVLMTLCEIFYFAVLRLD
NLDPILYLLFSAMIGVSFMLFCVAIVYDLFHIPYAKIPHDYSRRLFIKMVFDVTMLILAF
SYIAKGFINGMKAPRIKEVDVFINGLASELSIVQITDLHIGKTLGKAFMDDVVKQINTLD
ADIVVITGDLVDMPVGQIGDKLDSLSSIESRLGVYYVPGNHEYFYGVNAIMDHVRSLGVH
VLSNRSIVINHTINLAGVMDMMGKRFDFEPPDLAKALLHVKPELPTILLAHQPKFVNEIN
DEKIDLILSGHTHGGQIFPFGLLVLLDQPYLSGLYQHSKQTQIFVSNGAGYWGPAVRILA
PSEIIKLTLKVKKA
>A0A5N5T5V0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Armadillidium nasatum|TrEMBL
MEGAADLIIVDARSSKGLKPESFCACVRSCDGVSSCVVVAIVKKSALERDSPRVYRYLNA
GINRVLMESTTPGVVTNELIQLERGDLHVLKQQKILTAFIAALDSCKDLVHITDAQHRIQ
HINRACEAYLGYKIEDLYGKTIWEVHGSDHHRQELRTPSDVRSVDSLQTSTLRKKLSIDY
KGSELTEIKEGKVGLDVSEAVNLQMRRGKEWEGLFSCRRKSGDIVHFSSKVTPVSCHSRQ
NEFFVYWSDGHHGERVEPFYARAPSIKSHRKGSYDIRSLNSDGERRKESLENELHGGVLS
APIQRDKFTFSRASSQGFREGSIIRRQSVAKLHNYMLEAPITRVVSIITAAQDSSPAYIA
QALEKVLEILRSTELYNPQPILDSHTKSVTTDPVATDLLGALLSHSPKPLSGGRRSSSDQ
TINRLQNARPSLPASFQQASSAIKEILAEDLTWKFDIIKLEKLTDKRPLVWLGMNLMCQL
NVPQALCCDEQTLQNWLTLIEANYQSGNSYHNSTHAADVLQTTAFFLEKERIKNMMDPLD
AAACLIAAAVHDVDHPGKNSQFLCNTNNELAILYNDQAVLESHHAAVTFKLTASDDRVNI
LKGLDLESYKFVRKNVIDMVLATDMAKHFEHVNKFINMLDKCVTKIDDDGDQLVRSVLFS
QETIEPTVDLTLVNTSENIEIIKRMMIKCADINNPLRPIHLCVEWANRIANEYFNQTEEE
KRRKIPVVMPQFDRTTCSIPKSQIGFIDFFIFDMFEAWHELAQIPELMGHLKENYHYWKE
MDERERKTLTASLELKSPSSGGSQSNLDSSLKVEEGVIVEELT
>A0A3Z2F675|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella typhimurium (strain ATCC 68169 / UK-1)|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A6J3I8F1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sapajus apella|TrEMBL
MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRNIQLPPLAFRQLEQAD
LKSESENIQRPTSLPLKILPLIAITSADSSGFDVDNGTSAGRSPLDPMTSPGSGLILQAN
FVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFA
ALTNLQDRAPSKRSPMCNQPSINKATITEHLGMIHGCNITAEASLENFFSYLRKWD
>A0A6A1RK69|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter guillouiae|TrEMBL
MQSEILPQTDKDRVIIQITDTHLMDKPDAEFVGINPEETFHAVMDDIQQRYKNIDLILHT
GDLAQAAFPETYARYLEYMQRFGVDFYQIPGNHDNINLFPFHSPEPIPAVIELDQWRIIL
LNSAVGGRTDGNIQTEQLVHLKRLLEQLRDKFILIACHHNPFDMHSKWLDQHKLKNADEL
KAVLEPFDNIKAVLHGHVHQESYNVWNGIQFISTPATCVQFKPLSQEFSFDPIAPGYRCL
HLKANGEFETAVHRLDHFKVTINEEISGY
>F4V676|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli TA280|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7J0B9K3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MKTIEKYLIGAILTVFLPLTAASCSSSDDNPPISDSGIHFSVPAKIDIMQGGDYTFNVPS
GSVPLTTDFLMLEASNGVLHISPIVSATENSFTVRFNPSVTDGSYRAYIKRDDRRIPLGQ
LSVAIVESIIEPAEGATIYGLVSTDEGGVKGVVVSDGIEVTTTDENGVYNLKSNKHYGYV
FISVPSGYEVETDGVLPRMYRLTTADNTKAERADFRLTQVDGQDTYKVFFLGDMHLANRT
DDAAQFRQFTADFNNYRNSCSGQKMYAITLGDMTWDLYWYDNKYEIADYIKTINEQVKDI
QIFHTMGNHDYDYKAFNDFDAALQYRTHLAPGYYSFNIGKVHYIVLDDIDCDGYDGTTAR
LYTKNLSDDQLTWLAKDLAYVNKSTPVIITAHAPFFRPTETGSYKYDHDAASTDRLLSLL
DGYKVHFVTGHTHMNYNVPAGHQVSGGRDIMEHNVAAICASWWWSGHLTPGLHLSTDGTP
GGYAIWDINGTDIKWIYKGTNLNEDVQFRSYDLNQVRFSLNDVPDMSGTATATNAFNKYI
QAYPANSNNEVLINVWNWNPSWTITVTTESGQTLTCTPVGAYDPLHIAALTVKRFNKANL
KSAPSFITELFVHFFKVKAPDATSTLNITVKDEFGHTWTEEMKRPKAFSTDAYMQ
>A0A4R2XQZ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Raoultella ornithinolytica|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLEAIHASQRQCDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
RWQILLLDSQVFGVPHGELSDFQLEWLEHKLAAEPERYTLLLLHHHPLASGCSWLDQHSL
RNAAALDRALAAFPRVRHLLCGHIHQELDLNWGGRRMMATPSTCVQFKPHCDNFTLDTVS
PGWRWLDLHPDGTLTTEVCRLSGVKFHPDIASEGY
>A0A385NCT5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. WCHA55|TrEMBL
MTLNNEKSWTIIQISDTHLMDQDHLEFVRMNPEQSFHHVMQHIVERHPQLNAIIHTGDLA
QVPVPRTYQRYLDFMQSLKTPFYQVPGNHDNAEHFPFHQQLNKVHVIHFGPWSIVLLNSA
VKGKIDGWVDEAQLKQLEQILQEFAQQHIVITCHHHPFEMQSKWIDQHKLKNTQDLTAVL
AKYHNVKIVLSGHVHQESWREWHGIQFYSTPSTSVQFKPLSDHFALDEQAPGYRILQLNA
DGSHETHVERVLHAQQKINVEISGY
>Q16JF3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aedes aegypti|TrEMBL
RLISDLKFPNLLPPNPPIKILIAFCKNDPVFEALVTASHRLNFEPTFVKSAETAIEAFQN
AATGGHHIIVVDARYPRIIEADVLGRLHRPLSGNTLLSNSMYCACRAITLFEKDDTAVIS
LLDVGFNRCIIESPHVSICSSELRQIQHSLVRPQNVISTQQALYTALHRSREAVIITDDS
LRAQYANRASEKVLNMKLDEIVGRSLNDLVTADISNILSHTTRHKDYEGFISTRRKSQET
LHIHVRAVPVSCIGRNPTHLVLILEQTSGTTLSALATLPHGKEVARGSLHSIRRGSFDVR
STASDGLRRTSLAKLSQLPLEAPITKVLSLLAQVQENCSADESKLLDRVMEFLKREGLYS
PQMKEIRTEDPVATDLIGALLTQGPTNILSSRRSSNDSIIRGGGRPSTGSIVFNKTRESS
QLSELLNSALSWDFEIFKLEELTEKRPLVCLGLELFRRFDVYNTFCCDEVTFKLWLIEIE
KKYHSDNTYHNSTHAADVMQATACYLQQLSNRETKVMDRMDEATALIAAATHDIDHPGRS
SAFLCNSDDRLALLYNDICVLESHHAATTFRLTMADDKINIFKHLDRESYKLARSIIVDM
ILATEMTRHFEHLAKFVSVFGTDVDSKETTHDNDDNQILIRRMLIKCADVSNPTRPLKFC
VEWARRIAEEYFTQTDEEKHRNLPIVMPMFDRTTCSISKSQIGFIEYIIHDMMDAWNSFI
EMPEIVRYMEHNYSKWKLFEEQGINTLSDIKRKQLTLNSETTGSSSIEEL
>V7IQN6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Cubana str. 76814|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A855ICB4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio breoganii|TrEMBL
MEPQIVATEETVQLVQITDTHLFADDEGCLLSVNTGQSFIATVNDIVERNVEFDAIVATG
DISQDHSAASYTRFADGIKPLEKQCYWLPGNHDQKSNMVTVLPSPQIKEVGHVLAGEYWQ
IIMLDSQVEGLPHGYLETDQLELLDNKLAEFPERHTLVLLHHNALPIGSAWLDQHKLQRA
HQFWEVLGRHQNVRAVLGGHVHQDFEKEHNGVRVLATPSTCIQFKANNDEFALDTLSPGW
RHLQLHKDGQLESQVYRLEEGCFIPDFEAEGY
>A0A7D5LS57|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas yamanorum|TrEMBL
MPSVSTLNPDAAALLVQLSDSHLFAEADTQLLGMNTRDSLQRVIDRVLARQPQIDLLLAT
GDLSQDGTLASYQAFRDMTRQIPVPARWIPGNHDEPQIMAHAAINSALLEPVVDVGNWRI
TLLDSAVPGSVPGYLQDRQLQLLAQSLSEAPTRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVKAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEEAPGYR
WLRLHADGRLETGVERVEGFVFQVDYGSNGY
>A0A081RZP2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photorhabdus temperata subsp. temperata Meg1|TrEMBL
MESQFKLPVVEGTTAKILQITDTHLFAGKEETLLGVNTYRSYHAVLDAILKQNADIDLIV
ATGDLAQDQSLEAYRHFADGIARLPAPCVWLPGNHDYQPAMVDALAAAGVSPSKQILVGE
HWQLLMLDSQVPGVPHGELSEYQLEWMKKCLDMYPERYTVILLHHHPLPSGCTWLDQHSL
RNSHILAQYLQGYTRVKAMLCGHIHQEMDLDWNGIHMMATPSTSVQFKPHCTNFTLDTVA
PGWRYLELSISDRGEFSLTTQVHRLESNEFCPDLDSDGY
>A0A084TGA9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. ER1A|TrEMBL
MKTTPSDESQLSSVRLLQLTDTHLFAPQDGCLLSVNTQESFNAVVAEIVAQGTQFDALLA
TGDISQDHTEASYEKFVAGIEPLALPCYWLPGNHDYKPCMNSVVSSPLIQDVTHVLLGEK
WQVVLLDSQVVGVPHGRLSDSQLEFLDRMLSTHCDRHTLVLLHHHPLLVNSAWLDQHSLK
DADEFWNVVEKHDNVRAVLCGHIHQELDEMRGGVRVLATPSTCVQFKPNSNEFALDVRSP
GWRELELREDGRLHTEVKRLANGSFRPDFNAEGY
>A0A850F1K0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacteriaceae bacterium BIT-l23|TrEMBL
MESQLNLPVAGGASIRILQITDTHLFADKSGTLLGVNTWESYQAVVAAIHARQNAWDLIV
ATGDLAQDQSAQAYQHFADGIAGFSAPCVWLPGNHDFQPAMYSALQDAGISPAKVVYAGD
AWQILLLDSQVFGVPHGELSDYQLEWLERQLSRAPERHTLLLLHHHPLPSGCSWLDQHSL
RNSPALDDVLARWPRVKTLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIP
PGWRWLELAPDGTLTTEVCRLETQDFSPDTESEGY
>A0A2R7NFI6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sp. HMWF017|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQANEHPYEVILAT
GDLSQDHSPESYQRFASMMAPLGRPIYWLPGNHDDSPLMTEYLHAAGISESKQLVGDHWQ
VILLDTQVRGKPHGMIGDHQLAALDRALRQYPDRHALITLHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLYPDGRVASEVWRLPVGQFVPDPNATGY
>A0A3Q9J250|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Microbacterium oxydans|TrEMBL
MRTRHGIGAIAVTCALTLLVGAAATPAFAAAPPLTEGFTDATASQPPAGWSIDNTNVTGM
RADWQGWSFHTSAEVVSTWGNSGDRGSFTRADAVTAVVHSDANRPTDGRFSSVLWAPAVD
LQSQDGAVRVRFDSHYKQGQSPQTAQLVARFDDAAPVVVESFARNRLDEQVDVSIPVPAG
TDAVTVGWSYAESSNNWFWMIDDVQISEAPPADAAPRILSAAKPVARAGATVPVKVGGLR
PGQQLTASFGDAGAAVPGIPVADAAGETSFSVALPADLAPGSVTLSLGGAGIVSTRLVIT
VLAADDPDTSTTEQLLWFDGFETDSWTSEGAWTLSNLDSVIAQYGTDRRHAFTRASGRIA
VAEATSGAFAGSLASSPIAVKAGDALEVRLDSHYRKRGGTQHGTVTAVFDEGTETVLREL
SDADEESAQLRLPVTVPAGASAMTLRFVFDAPGAAGSWMLDDVQVVRPLAALAEGVEANT
VVDIFSDVQGATTRLSQNVLPGFRAMAQTADVLVSNGDLVSNGSTANYTSYLSALAAGGG
GEYGTVVSTIGNHEYYGSEGSAVYRERFLDSTGMRDIGGQGGLWGEVLVDGQLPLIWIGS
EFYDYTAKTGAGPFVDFSEEQFTWLRDRLAHWRAQDQPVLLFSHHLLPYSVSGSYARFYE
NDFGQEEARFAALLAQNPNVIMFNSHTHWSPTLNDWSTELRPDPTRASGPTVVNTGAVTT
MYGPSGDWEEKAVGGADPVGLRAALYDDRVRVTVYSFSTAGATEIKHVDIPRPTDAPVDP
VDPVDPVDPVDPAVALSTQTVAAGGRVTISGTGFPEAAELAIELRSTPVRVGVATADADG
SFRTAVTIPAKTPAGAHTLAVILPDGTEATAPITVTRAGDGSGGVAPGTGTGTAPGSGSS
GGADASSTGGDLATTGGAPGWYLVGGALLFLSLGGALVLRRRRGRS
>A0A4U6GZ30|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. wls714|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSSLQEAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRAKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVCRLQGNRFHPDTASEGY
>B2VGH8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99)|TrEMBL
MDSLLKLPVASGSRVRILQITDTHLFSGKHETLLGVNTWASFDAVLDAIAAEHAHYDLIV
ATGDLAQDHSMEAYQHFAEGISRLPAPCVWLPGNHDYQPTMFRTLGASSIADQKQVLLGD
RWQVVLLDSQVYGVPHGELSDYQLEWLERAMAAEPQRHTLILLHHHPLPSGCSWLDQHSL
RNPHMLDAVLQRYPLAKTLLCGHIHQELDLNWQGRRVLATPSTCVQFKPHCTNFTIDAEA
PGWRCLDLQEDGRLETEVRRLNTRMFNPDLDSEGY
>A0A0W8JJA4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. MEBiC08052|TrEMBL
MTDTHLFASDEGSLLSVNTANSFKAVVQEVIARDVDYQLILATGDISQDHSEASYQLFVD
GIAPLQKPCLCLPGNHDEQIAMKNILANSQIVQPRHVTVGAHWQMILLDSQVSGVPYGYI
SPEQLQLMDDILRETQARHTLILLHHHPLLVGSRWLDQHTLKNSDSFWDILLQYPHVKGV
ICGHVHQVMERDYHGIQVMSTPSTCVQFKPHSDEFALDLVSPGWRELELHPDGQLTTQVG
RLKQGLFLPDFSANGY
>A0A679IWU0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Variovorax paradoxus|TrEMBL
MHGTRLADGVSRAVPEPIAPMPIRPLSALTALLHVYIALRLVPALAVLTPAWPLALVALA
VSAFTIPLPFLSRRDGASPGTALKWIGLISMGWFSSMFVLTLVRDAALGLTWLAGVAGGV
QVQWAALKPWSALAVLAMATATSAIGFLNARRTASVKRVEVPIRGLPQALEGFTIAQLSD
IHVGPTIRNTYIQRIVDAVNRLGADAIAITGDLVDGTVAELREHIAPLAGLRARHGTFVV
TGNHEYYAGAHAWIDELRRLGLKVLLNEHVVLQTRNVRGAQTDEELFESALVLAGVTDFT
AGHFDAAHASDPHLALYDAPPLVHTRVLLAHQPRSAPVAAAAGYQLQLSGHTHGGQFFPW
NLFVPMQQPFTAGLHRLHDMWIYVSRGTGYWGPPKRFGAPSEITLLTLVPARD
>A0A221K279|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sulfitobacter pseudonitzschiae|TrEMBL
MKRIIHLSDLHFGRDRPELMAPLLERINGLDADLVAISGDLTQRARARQFQQARTFIDAI
DGPTLVVPGNHDTPLYNFFERVVWPFRRYRSWINRDLQPVVHTPQASVVGINSVNPLGIQ
RGWFSPKDIRRVRRGFRDAAEGAMRIVVVHHPLEHLPGEDKKLMRGARAAIKALGEAGTD
IVLSGHLHSWRAETFAHIEVHRGVIQIHAGTGLSNRVRGEPNDFNLLHLDGDLVHVERFA
AVESTRSFDHHQKVSFTRDVDGWTQCTPITQQK
>A0A8D0G9W7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Sphenodon punctatus|TrEMBL
MPPLSFAGWRLVEAIKLFFLSCSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRE
SFLYRSDSDYYLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDR
APSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFK
RMLNRELTHLSEMSRSGNQVSEYISSTFLDKQHEVEMPSPTQKEKDKKKRPMSQISGVKK
LMHSSSLTNSSIPKFGVKTEQEDILAKELEDVNKWGLHVFKIADLSGNRPLTVVMYTIFQ
ERDLLKTFKIPADILITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTD
LEILAAIFASAIHHVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCD
IFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRI
QVLQNMVHCADLSNPTKPLQIYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEK
SQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPASDDQEEGRQG
QTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVGEEVE
EEESQTDPCVLEEDCSPDT
>A0A5E4LIQ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKNDSMKLLALSDLHADEELLDRLRALSARSSYDAVLFCGDLTNRGPVSYAEEAVKLFPN
VYSIYGNMDTPEVVQKLSSLGVLVHGKKVRLGEWNLVGLGGSNPTPFHTPSELSEEQIES
ALARAGVNEFSVVLSHPPPFGVFDTVGQVHVGSKAVRRMVEEKKPIMLICGHIHEYEGKQ
ILGETLIVKLGPAEKMRAAEITISDSIDVKFISL
>A0A2A9F1K7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. ES.051|TrEMBL
MQAFSDSIKLLQITDTHLFAADEGSLLSVKTVDSFKAVVGEVLRRNVAFDYILATGDISQ
DHSSESYQRFAEGIEPLEKDCFWLPGNHDYKPNMGSVLPSPQIQAVEHALLGKHWQLILL
DSQVVGVPHGRLSDQQLVLLEEKLVEYPERHALVLLHHHPLLVGSAWLDQHTLKDADAFW
QVVNRFDNVKGILCGHVHQDMNVLHNGIRVMATPSTCVQFKPNSDDFALDTTSPGWRELQ
LHDNGDITTQVNRLPKGQFQPDFSSNGY
>A0A8F9ZT65|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gilliamella sp. ESL0443|TrEMBL
MASLLTLQIKNKHCANILHITDTHLFADEDGALLGIKSNASFLSVINEIKRGNRKYDLIV
ATGDFVQDGSKKSYARFAEQIKQFNTPCVWLAGNHDNFSYMQEVFSNYQLAENKVVSLGD
NWLIVLLNSQVVGQACGLLPQSELQFLEKTLLAHTDKNVMVFLHHHPISSGCHWLDEHIL
KNSNELEEIVKKFPSIKGLGWGHIHQQQDHVWHNCHAFSTPSTCFQFKPNCYEFQLSNDE
APGWREIKLNEDGTIESSVFRIADNLFLPDVSQKGY
>A0A5Y2QME7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. arizonae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLVNFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A7V8TSA8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ectothiorhodospiraceae bacterium WFHF3C12|TrEMBL
MHEYTRSSQDCLKVLQITDTHLYADPQGELGGLNTERSYCEVMEKVLRDHWPVDLILATG
DIVHDGSVAGYRRFKGQFEDLAVRTLVIPGNHDDPDALRQVMQGGRVTCSENAILGGWQF
VMLDSVLPGADGGRLGSDQLQLLERCLADNRGLHTVVCLHHHPVDMGSEWIDRIGVDNAD
DFWAVIDRHPDVRAVVWGHVHQDLHRRRGSVELFASPSTCIQFKPEEEEFAIDEAPPGYR
WFRLYRDGRLESAVERLEEPPGQLDIGCGGY
>R1HCX9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas molluscorum 848|TrEMBL
METELPQAPDGSVRLLQITDTHLFASGEGSLLAVRTADSLAAVLERVQANGHPFDLILAT
GDLSQDHSPESYQRFASMMAPLSRPIYWLPGNHDDGPLMTEYLHAAGISEKKQLVGEHWQ
IILLDTQVRGKPHGVLGDHQLAALDLALRQHPDRHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHQGVRLIASPSTCIQFKPLCEGFTLDESGPGW
RYLTLYPDGRIASQVWRLPLGQFVPDPDATGY
>A0A2T7AU89|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cronobacter muytjensii|TrEMBL
MESLLNLPVAGGASVRILQITDTHLFAGKNDTLLGVNTWESYQAVLAALHAGQRECDLIV
ATGDLAQDHTPEAYAHFAAGVATLPAPCVWLPGNHDFQPAMYSTLQDAGISPAKRVFAGD
HWQVLLLDSQVFGVPHGELSDYQLEWLERMLQQAPERHTLLLLHHHPLPSGCGWLDQHSL
RNAQSLDDVLSRYPQVKHLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCAGFTLDTVA
PGWRWLNLHPDGSLTTEVCRLEGAQFRPDTASEGY
>T0NTL1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Camelus ferus|TrEMBL
MFCSNCGQRRSARSQLGYGLYVMLTDFAHFDVENGPSPGRSPLDPQASSSSGLVLHSTFP
GHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTI
LTNLHGTSNK
>A0A520Z0D0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonadales bacterium|TrEMBL
MKRPIIVSRFPVFEKDNSKDLLDSQTLELPASDDNATLRVLQITDCHLGEAIGEVLAGMD
TDASLASVLELLVAEQSEHGEINAELLLATGDLSNLGTASAYYRLEKILQPLGLPMAWLP
GNHDVRDLMIDSVGIDRMPRMVRLGRWAICMLDSAVPGQVGGELGATELNELRIELDSLP
ADVHIMICLHHQPVEVGSAWLDQQKVADADRLFALLKNERRVKAILWGHVHQEFYGTHPG
LPGVKLIASPSTCIQFAPGQRDFKLDTAMPGYRWLDLHADGSIQTGVSRVEGADLRIDLA
SSGY
>A0A653PIV4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Plantibacter sp. T3|TrEMBL
MSLRTAEYPRPDHFLLHVSDTHLLAGGGSLYDSVDSETHLRHLFAEFEASGGRPEAIVFT
GDLADKGEPDAYDRIRSIVEPVAERLGSQIIWVMGNHDDRQAFRAGLFGEVPTTRPVDRV
YDVNGLRVITLDSSVPGHHHGEVSDEQLDWLAEELSTKAPHGTILAMHHPPVPSVLDLAV
SVELRDQAKLAEVLEGSDVRSIIAGHLHYSSTATFAGIPVSVASATCYTQDLNVPVGGTR
GRDGARAFNLVHVYGKTVLHSVVPLGETPPLHYIDAEESARLLARDGIELPVSDTVPVQP
EPPLTMPIGVLV
>A0A3A8EHA8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter tianfuensis|TrEMBL
MPFITQSNKRSDWTIVQISDTHLMDHQDLKFVSMNPEQSFHDVIHHVQTQFPKLDAIVHT
GDLAQVPVQKTYDRYLQFMQTLNTPHYQIPGNHDRAEIFPFHEQANRAHAIHFGAWTMVL
LNSAVKGKVDGWVAEAQLQQLDELLSAHPEQHIIIACHHHPFAMQSHWIDQHKLKNAEHL
MDVIAKHANVRIVLCGHVHQDSSNTWENVRFLSTPSTSVQFKPHSPTFALDQELPGYRVL
HLYNDGAFETEVFRVKMTQPQINAEISGY
>A0A6S7FA30|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter insolitus|TrEMBL
MARIHSLTRRDDAPAMLVQLTDSHLFGEPETSMLGVNTDASLRAVLRQIEADGKHPDLLL
ATGDMSQDGEAAAYRRLARVLSEAPALEQACIRCLPGNHDLPAVMRQELPEWSAPVTDVG
AWRVVALDTTVPNSNAGHLPQSQLDLLEAALAEAPGRHTLIAMHHNPMQIDSHWHDSMMI
DNPQALFKLLTRWPQVRVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNMA
PGYRWIKLYQDGSMATGVRRVQDALWHPALTSQDKAQAA
>A0A2S9YAZ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enhygromyxa salina|TrEMBL
MARDIYNFIWTLPPPPGPTIGPVPQRSMATVAARHASTRGVILYPAFMTPLVYIEGQEAE
PWLELLIATEHPLTRAMVNAQLKISAGLRSEKPVSTAPLFTSATGNIIVESAGEVSDDGE
TIIETHSKFAGILHPSFGEALRDKRVRRVYRVKIQATAIPYVAPTGELNYSFLERKWTDY
AMRDGAVTRLTRRARVGRELSDLMIREMLTRRFGPDNRSNQNSIPGRGRYAFPMHGNTVD
IRKVDPEQPIQSYHPMVVMTGDDAHAHVNLGHVSDIHINTRWQILGKSNARVIEYGAGQY
EDESPEIGSLLAENNRSFHAVLGRLAGSEADAIIVGGDVVDHIRNAYDPGCVLRSDSTPR
QIWDAMNIEGDAYTDATYPVGLDLIAFFSFMYEAMTVHQKPVFGITGNHDCYVDAFGISP
RLNAELTASRTNEGIPADLNLTFYEALLAFGPSAGLLRSASSSFDADWFDWFHLVLTPFN
DWWFKFPNQSLVGLGWGTTEDLIDPFGGQSGGHLPRSDDAISDAQLALLQRAVDERGDRK
VTLTSHFTFLSYIESVPMHPGGARSSRGTFRLNENTLGTESYSHFEMGTFETNRATLMNM
LAGRQLQCVLTGHSHRRGLHLLGDRNGDEIPADLFDTDPRDPLSLCRIPAGLTAAEPAII
VSDSGGPYPRHNRDNEFLGWGSDRPGGTLVRFDRADGRLTDVRTLTATRRRKARGAVVMD
YVDVSSEGVFNDNRMQTQWVPADVDSGAAPASASPVWFIDANLTTQVHSTWGMYIEKIIF
AGRHGDRWIHVESTYDRAHNAFAVPAAQTDDFRTWARLVLQPTRYVSIKMGSRNGFISGR
YGWGSHWNFEVFAQPIFQHQPDARGRMVRFVSYRIFRPQREIAITGRDVAWREAPNFDWR
MANDPKYAD
>A0A6M8B2P5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Thermoleptolyngbya sichuanensis PKUAC-SCTA183|TrEMBL
MPSSAGSPSAGLKIVQLTDTHLFADEQGEMKGCQTGRSLQTVLQAVAQRQPRPDLLLLTG
DLSQDETEESYRVLLRLISPLGVPALWLPGNHDQAIALMEQVLSVFPASPQKCLQQGGWN
LILLNSSQWNEVSGRLSDDSLRWLDTQLRQFAHLPTLVALHHPPLAVGSAWMDAIGLQNR
EDLFAVLDQHPQVKLVVFGHIHQEFDQMRQGVRYLGTPSTCVQFSPNIDEFSIDLTRQPG
FREITLYPDGRYETQVVRAERQASLV
>A0A553QH11|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Danionella translucida|TrEMBL
MLGCGLSAHTLTTPTCRWSTRRASAPVHFRATCLCQRPTPSVTLSMGVVEAIDVSPSSCP
SPVPGGFRLAHSSSYSPLQGRRGSELELGAASDGVLDGGSQATERRTPFMDLFCDTCSKP
WLIGWWDQFKRMLNRELSHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTLREREKPMS
HISGVKKLTHSSSLTSAALPRFGVKTEQEDALARELNDLNKWGLNIFQVAEYSNNRPLSC
IMFAIFQERDLLKTFRIPVDTFITYVMTLEDHYHANVAYHNSLHAADVTQSTHVLLSSPA
LDMLDSELALMYNDESVLENHHLAVGFKLLHEENCDIFQNLSKRQRQSLRKLVIDMVLAT
DMSKHMSLLADLKTMVETKKVTSSGVLMLDHYNDRIQVLRNMVHCADLSNPTKPLAVYRQ
WTERIMQEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWGDLVHPD
AQEILDTLEDNRDWYQSTIPQSPSPPPVGPDNELESCRNKFQFELTLEGETGEDSSHNHI
CIHDQEAQKEDEEAEDAEEDEAEEQMEDGEEMTEVMLERSGRRRLQVQSVVEEEDERQSD
ESPVEETEEEKSSSPTDDT
>A0A5E7UBW3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MLTTADPALLVQLSDSHLFAEANGTLLGMNTRESLQKVIELVLGQQPQIDLILATGDISQ
DGTLESYQQFRQMSAQIDAPARWIPGNHDEPQIMAVAAVQSALLEPIVDIGNWRVTMLDS
AVPGSVPGYLQDDQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPEAFFEV
LDRFPQARAVLWGHVHQEIDRERNGVRLMAAPSTCIQFEPGSEDFKVGEQAPGYRWLRLL
PDGRLETGVERVTGFAYTVDYGSNGY
>A0A5E6UPJ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTPADPALLVQLSDSHLFAEADGALLGMNTRESLQKVIELVLGQQPQIDLILAT
GDISQDGTLESYQQFRQMSAQIDAPARWIPGNHDEPMIMAQAAVQSTLLEPVVDIGNWRV
TMLDSAVPGSVPGYLQDDQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQARAVLWGHVHQEIDRERNGVRLMASPSTCIQFEPGSEDFKVGEQAPGYR
WLLLCRDGRLETVVERVTGFDCTVDYGSDGY
>A0A5E7QA53|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MDTSNTLHWMHISDLHKGQDGTSHSWPLVRQQIVQDIISQIRRSGPIDLVIFSGDLAFKG
SAAEFAEVKADLVKLWDAFGTDGGNPVLFIVPGNHDLVRPDADSVFLHVADNLRENDSAR
RALLEKPNFVYRKEVNACFENYTSFVASLAAAGIPTATVQEGLFPGDTSAILKVNGLNVG
LVGLNSSWTHLSNEIPRSHLDIAIEQLSSVTGEDFPGWAMLNDINFLVTHHPADWLSPHA
LEEFQSSVFVPDYFDAHLFGHMHDNLPSEQTIGAHKSRIFQAASLFGLEKVRGVADRRHG
YTFAKLEVVNEVCEVWPRRIIQKANRVWEVEADGRVLKGDERSFTFPWPLRSFAPIKKH
>A0A448KHV7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus ducreyi|TrEMBL
MGNFYSLGKKEPIIRLLQITDCHLFSSESECLLGINTTKTFQAVIEHIHQTDFAYDAVLA
TGDLIQDHNPEAYHRFAEMAKQFVKPLFWLEGNHDQQPQMSLYLGKYPHIQPEKQLLAGE
KWQILLLNSQVAGAPSGYLSAGQLAWLNSKLAKHLDRYALVVLHHNILPTNSAWLDQHCL
KNSEQLAKVLKSYRNVKAILHGHIHQEVDRVWQGYRVLATPSTCIQFKPNCRDFTLDMLP
QGWREISLLEDGSIETTVKRLASNQFLPDFQSKGY
>A0A3M9ZAX9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Leptolyngbya sp. IPPAS B-1204|TrEMBL
MPLLSPLQVVQLSDTHLFADPNRELLGLSTADSLKTVLDSVRQIQPKPDLLLLTGDLSQD
ESAKSYERLRDLLEPLQIPAYWLPGNHDYPPLMAQILVTPFIATDKVFQGGGWNFVLLNS
MATGKVYGELSAASLDWLEQQLQQCPVQPTLIALHHPPCPIGSNWMDQIGLRHPEALFAV
LDRYEQVKLVLFGHIHQEFTATRAGVQYLGCPSTCVQFKPQETNFAIDDQRPGFRLLSLY
PGGEFTTTVKRVNYQPLPDLAATGY
>A0A8J6SLV8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trichocoleus sp. FACHB-40|TrEMBL
MIPPKPLAIAQITDIHLFADTKKELLGLPTEKSFHAVLEQLQILLPQLDMLLLTGDLSQD
GKAESYQRLAELLSPLSIPTYWAPGNHDQPLVMQQVLKEAPISPEKSFAAGGWQFLLLDS
HVSGCVHGKLSPDSLVLLDTQLKLASARPTLIGFHHPPFLVDSDWLDGSTLQNPEELFAV
IDGHPQVKLVIFGHIHQEFYQRRGGVHYLGSPSTSIQFEPHSHNFSLDKVEPGFRLLNLY
PDGSFETRVQRVTYVHELDLAATGY
>A0A2G9RGU1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lithobates catesbeianus|TrEMBL
FDVENGPSSGRSPLDHQASPGSGLVLHTNFPSHNQRRESFLYRSDSDYDLSPKNMSRNSS
AASEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNVHGAPNKRSPMSNHPQINRVNIQGQS
LQQFSLTLCLGVVVFHLFM
>A0A8A0RRP0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Koleobacter methoxysyntrophicus|TrEMBL
MKKSRLAFIALVGIIGALIFIILFGKMDVNINAFEVQLSINIIEPGYTKLLFPPLGEIKA
KTHSSPIQFTVLLKNINPEIVKEVINNPDKERVFNDIKIKSIESVKKFIFKLLFLSVLGS
GILGYLFKFKAVSEILVCSLIGFLIVSTFIFWGYLTFDHNAFLDPEYSGVLKDAPWIMRL
AEETIASVDKLGNMLEVTAQNAYLLFEKLDELEPLESDGDLIKVLHISDIHNNVAAMDFV
EQVVQSFDIDMIIDTGDITDYGTPIEGSLLNRIEKLKIPYIFIAGNHDSPSIIDKMKNLK
NVKVLEEEAVEVKDISIFGIADPASKTNDIKPATKIDFEKDIDKITNKLNELENTPQILA
VHNPRTGRAFKGKVPVILYGHTHSFEIEETQGTIMINAGTTGSAGIRGLQAAKEIPYSMV
LIYYDKRNTHFPKAVDVIKIYSIKKGFTLERIWLSD
>A0A7X4XU37|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. V26_P1S5P106|TrEMBL
MNVSPSLSPSDHIKLVQITDTHLFAPDDGCLLSVNTADSFRAIVQAIIEQQIPFDAILAT
GDISQDHSAESYQRFAAGIRDLQKLCFWLPGNHDYKPNMGSVMPSAQIQALEHVLLGKHW
QMVLLDSQVVGVPHGRLSDYQLGLLDEKLTQYPDRFTLVLLHHHPLLVGSAWLDQHTLKD
SDAFWHVVGQHRNVRAVLCGHVHQAMDCEYQGVKVMATPSTCVQFKPNSDDFALDLCSPG
WRELELHHDGEVSTQVKRLRKGAFVPDFTSSGY
>A0A839D2T1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas caviae|TrEMBL
METELPQAPDGSVRLLQITDTHLFASAEGRLLAVPTAQSLAAVLERVQANEHPFELILAT
GDLSQDHSPESYQRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGDHWQ
VILLDTQVRGKPHGVLGDHQLAALDQALRQHPERHALIALHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHHGVRLIASPSTCIQFKPLSDGFALDESGPGW
RYLTLHPDGRVASQVWRLPLGQFVPDPNATGY
>A0A1W6KF39|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter salarius|TrEMBL
MRLVCISDTHSMHRQVVVPDGDVLIHAGDCLGVGTLEELEDLDNWFSEQPHRHKILIAGN
HDWCLQDEPADAEALIRNAVYLRDRSIDIEGLKFWGSPWTPIFFDWAFNLERGAPIAERW
AQIPSDTDVLITHGPPAGILDKVNESLAVGCNDLARELERLTLKLHIFGHIHESYGQQML
NDCLHVNASTCTGQFKPLNPPIVVDI
>A0A7T5QPZ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium carotovorum|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKARQDAFDLIV
ATGDLAQDHTLQAYHHFSRGIAHIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSAVLDRYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A6M1ZSK6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Anoxychlamydiales bacterium|TrEMBL
MNVFVISDLHLSYSVPEKSMEFFGDTWKNYHEKIKTNWLKKIKKEDIVLIPGDICWAMKL
KDALVDLEEINKLPGIKIILKGNHDYWWASNAKMIKALPPSIKFIQNNSINIGDVSIAGS
RLWDTNEYNFDEYIDFKHNPNKKDLEEKIQKELQEKIFLKELERLKSSLSQMNKNAKIKI
VMTHYPPISATLKDSKVSKILEEFNVDICVFGHLHSVKKNALNFGIKNKIKYIFASCDYI
DFDPIKIL
>A0A4Q4L741|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas koreensis|TrEMBL
MPSVSTITSADPALLVQLTDSHLFAEADGKLLGMNTRESLQKVIELVLGQQPQIDLLLAT
GDISQDGTLGSYQAFRQLSAQIDAPARWIPGNHDEPMVMAEAAVQSTLLEPVVDIGNWRV
TMLDSAVPGSVPGYLQDDQLQLLARALSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQVRAVLWGHVHQQIDRERNGVRLMASPSTCIQFEPGSADFKVGEQAPGYR
WLRLLPDGRLETGVERVTGFDFQVDYGSNGY
>A0A427HNX6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia rettgeri|TrEMBL
MDSQLEVTAKNSKIVRILQVTDTHLFANTENTLLGVNTYKSYQAVLDAITEGNLPIDLIV
ATGDLVQDQSPQAYQHFADGIARIPAPCVWLPGNHDYPPAMVETLRVAGISSAKQILIGD
EWQILMLDSQLQDVPHGELSEQQLEWMKASLDAEPERTTLIMLHHHPLASGCTWLDQHSL
RNSHILADYLKNYSNVKAMLCGHIHQEMDENWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELSINEQSQRHITTRVHRLDTREFSPDLDSDGY
>A0A2X2DIL4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Providencia rettgeri|TrEMBL
MDSQLEVTAKNSKVVRILQVTDTHLFANTENTLLGVNTYRSYQAVLDAISEENLPIDLIV
ATGDLVQDQSPQAYQHFADGIVRIPAPCVWLPGNHDYPPAMVKTLRIAGISSAKQVLIGD
EWQILMLDSQLQDVPHGELSEQQLEWMKASLDAEPERTTLIMLHHHPLASGCTWLDQHSL
RNSHILADYLKSYSNVKAMLCGHIHQEMDENWHGIRLLATPSTCVQFKPHCTNFALDTVA
PGWRYLELSINEQGQRHITTRVHRLDTREFSPDLDSDGY
>A0A223MZY0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio qinghaiensis|TrEMBL
MNVSPTLDNSDSIKLLQITDTHLFAPDDGSLLSVNTVDSFHAVVAEICAQHVKFDAILAT
GDISQDHSAESYLRFSRGISSLEKTCFWLPGNHDFKPNMGAVFPSEQIQQSEHVLLGEHW
QMVMLDSQVVGVPHGRLSDQQLALLDEKLSTHHQRHTLVVLHHHPLLVGSAWLDQHNLKD
SDAFWNIVTQHRNVKAVLCGHVHQNMDKLHHGVRVMATPSTCVQFKPNSDDFVLDRTSPG
WRELTLSADGQIETQVKRLANGAFQPDFNANGY
>A0A8I0JYE6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mycobacterium canettii|TrEMBL
MHRLRAAEHPRPDYVLLHISDTHLIGGDRRLYGAVDADDRLGELLEQLNQSGLRPDAIVF
TGDLADQGEPAAYRKLRGLVEPFAAQLGAELVWVMGNHDDRAELRKFLLDEAPSMAPLDR
VCMIDGLRIIVLDTSVPGHHHGEIRASQLGWLAEELATPAPDGTILALHHPPIPSVLDMA
VTVELRDQAALGRVLRGTDVRAILAGHLHYSTNATFVGIPVSVASATCYTQDLTVAAGGT
RGRDGAQGCNLVHVYPDTVVHSVIPLGGGETVGTFVSPGQARRKIAESGIFIEPSRRDSL
FKHPPMVLTSSAPRSPVD
>A0A0H3AM37|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFAAEDGSLLSVNTADSFAAVVAAIGEEQVEFDAILATG
DISQDHTPESYQRFVRGIQPLKKACYWLPGNHDYKPSMHGVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEYPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRIHLGARVMATPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A644UG52|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MTDIVFITDIHGKFDIVYEIFNRESPDYVLIGGDVTDLGQTLDGVIPFMEDIPAPTFVIP
GNCDNRDILPVLEASDAILIHRKSIDLGNITISGIGGSNATPFSTPFEHTDEELTAIVKE
VAAKTGKNRWNILVTHAPPFGALDEVAQDVHVGAHPIAGIVKEFDIICCGHIHEQKGICE
LKRRICVNPGPAYDGNYALITIEEEEDEPKIVLKNTRDPIEVTEE
>A0A644T9Y5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MNLTKHFQIINIEVEDKKLDDLKILHLSDLHINKKTSIEKILELVNFCNGLEFDFCIITG
DIIDTKVKFIKKQLEILNLLKKEVFYISGNHDLFYGLEDLKKELTNFIFMDNETFKINYK
NEIIHLAGLPDRFSKFFKIKREEKIIEDFLKNSPSIFISHQPKDYKIALNSNSNLFLCGH
THGGQIYPFHYLVKLVQPFLAGLFYKNKTAIYVNKGLGTWGVDFRFKADAEITILKLITK
SVK
>A0A822PCK7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella flexneri 2a|TrEMBL
MESLLTLPLAGEARGRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7R9R7H6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Methanoperedenaceae archaeon GB37|TrEMBL
MTRIVHLSDIHVSESYFLADVAESVLQSVNEISPEIVVVTGDLTHNGSHQEFRDVKEYMD
RIDCRNKVIIPGNHDSRNLGYLLFEDLFGARSQSHTFNGVTVVGVDSSEPDIDDGHIGRE
SYDWIAKNFETDDFKVFALHHHLIPVPMTGREVQIPVDSGDVLELLHRCGVNLVLCGHKH
VPWVWRLNEMFVVNAGSMSSKDIKARTTHCYNLIEVDRKDLQIYQVLPTGERRLIIDSNY
ESKNE
>A0A8F9Y0P8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dickeya zeae|TrEMBL
MESLLTLPVASGARVRILQITDTHLFADEQGTLLGVNTYRSYQAVLNAIAAQQMNVDLIT
ATGDLAQDHTQDAYTHFATGIRRLGAPCVWLPGNHDFQPAMVDVLARSGIAPSKHVLLGE
HWQVILLDSQVFGVPHGELSEYQLEWLDRNLRSQPDRHTLLMLHHHPLSSGCTWLDQHSL
RNAHSLDALLSRFPRVRTVLCGHIHQEMDLDWNGRRLLATPSTCVQFKPHCTNFTIDNVA
PGWRYLELLPDGEVETRVCRLEGNEFLPDMDSDGY
>A0A6A7YLZ3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas helleri|TrEMBL
MPNASTPTTEHPVLLVQLTDSHLFADADGSLLGLNTAQSLQQVVDKARAEQAQVDLLLGT
GDLAQDGSVAAYQRFRQVSEPLCANARWLPGNHDRLAQMREATVQTRLLDPVVDIGNWRI
ILLNSQVPGATPGYLEDEQLQLLARAVSEAPQRHHLVCLHHHPVPVGSEWIEPIGLRNAK
EFWAVLDRFPQVRAVLWGHIHQPFDHVRNGVRLLATPSTCVQFTPGSTDFDVSGEAPGYR
WLRLHPDGALDTGVSRLDNFVFTPDYSANNY
>N9PEC0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter colistiniresistens|TrEMBL
MTFQVSSLSQQDFVMIQITDTHLLEYPHLEFVGMQPEQSFHAVIDLMRQQHPHIDLIVHT
GDLAQSPTPLTYNRYVQHMQSLGIPFFQTPGNHDDVTHFPFHETDQTQPTVIELGQWCII
LLNSAQPKRIDGKIAEQQLQQLTQLLIQHPDRHVIIACHHHPFAMQSAWIDQHKLKNTSD
LLETIQPFCNVKAIVCGHVHQDSINTWQGVEFLSTPSTCIQFKPKSDKFALDEEHPGYRL
IRLKANGELETQVYRLPTSQRMNSSEVLGYD
>A0A2A7MH44|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Clostridium neonatale|TrEMBL
MRNNCSRSKNFIKRIEQFGADIEFDEKSKIVFISDVHRGDGGYSDSLRQNRNIYKAAINY
YLRNDYKLIELGDGDELWKNKNLVDIAYNYRDIFKILNEFNKKKNLYMVFGNHDMAKADK
DFILKQEKIFKQIGRRFGKDLLNLYKNIDFYEGIVLKYIPAGKKILAFHGHQVDFMNCDL
WRISRFLVRYIWRPMEGIAGFKEPVSPSSNYDKGTKIDMMLEKVAKKERKIIICGHTHND
IFPKVSEGLYFNDGCCVFPSSITTIEIKNGLISLVKWRIEVDNNNILFVKKNIIGGPEKI
EKYFEYARNL
>A0A2T8MEV3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella anatum|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A730TMS0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Rough O:-:-|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A1V3KQX1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rodentibacter heylii|TrEMBL
MRNTFVYRTEKPIVKLLQITDPHLFKDEKNELLGVNTQASFAQVLKEIQQDNTEFDVILA
TGDLVQDSSDEGYQRFVKMVKPFGLPVFWIPGNHDFQPKMVENLNQPPMEKAKHILLGEH
WQVLLLDSQVYGVPHGELSQHQLGLLKTTLEQYPERYTLIVFHHHLVPTNSAWLDQHNLR
NSHDLFDVLAPFKNVKAILYGHIHQQVDSRWQDYQVMATPSTCIQFKADSQYFALDKIQP
GWREIALYPDGSITTQVKRIQQAMFLPNMQEEGY
>A0A6P4LCQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila bipectinata|TrEMBL
MIISSQPNLAGSATTTATTTSTATNAAAHTSEESVPSNCNCSMVGSGGLVGVPLTRQAPV
MDAKTTGGGGGAEATTPTAGRDSLTRPASESELNVGTGTSGTSSSGGGNSRPGHRKSSLA
FALTPEDEPMDVYQRNLMDLKYPTVLPPNPQLKALLVFYKADSICEAVSAACQRHQLDVT
LVKSKEEALDTLQKSYATAQCYHLIIIDARSSKNLDAEHIARTIRHTHGHHLTTIIAVCK
KSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALH
RLKEVVLITDDVLRIQYANRATERLLNMRLDEIISKPLADIFVSDLSTISEQGKSIKEFD
GILTVRRKNQEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSL
HSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKV
LEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTATI
VPAKMKANPIIMELLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENV
CKAWLAVIEAHYHKSNTYHNSTHAADVMQATGAFITQLTNRDMMVMDRMEEATALIAAAA
HDVDHPGRSSAFLCNSNDSLAVLYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKEQYK
SARSTIIDMILATEMTRHFEHLAKFVSVFGGDESREPHAQTEEETSILMRRMLIKVADVS
NPARPMQYCIEWARRIAEEYFMQTDEEKQRHMPIVMPMFDRATCSIPKSQIGFIEYIIQD
MMHAWESFIDMPQLITYMQINYSQWKKYDEQGINTLADIMAKQPPVGKLANSK
>A0A7Z2MPJ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio parahaemolyticus|TrEMBL
MQSSNDSIKLLQITDTHLFAADEGSLLSVKTADSFSAVVHDVLRRKVGFDYILATGDISQ
DHSAESYQRFADGIAPLQKDCYWLPGNHDYKPNMGSVLPSPQIQAAEHVLLGEKWQLILL
DSQVVGVPHGRLSDQQLTLLEEKLTEFPERHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRCDNVKGILCGHVHQDMNVIHKGIRVMATPSTCVQFKPNSDDFALDTTSPGWRELE
LHTNGDITTHVDRLPEGQFQPDFSSNGY
>A0A7G3EXQ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIHAEKRPCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGD
QWQILLLDSQVFGVPHGELSDYQLDWLETKLAAEPNRNTLLLLHHHPLPAGCSWLDQHSL
RNSAALDGVLAKFPRVKNLLCGHIHQEQDLDWNGRRLLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLTGAQFRPDTASEGY
>A0A2N7WKW5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia rhynchosiae|TrEMBL
MSSHSFDLSRRGALKCLAFGGAGTLFVLAGGVLTPVHLALAADAKSSAANGVPLFLQISD
THIGFNKEANPDVAGTLKQTIEFVNAMPVKPALAIHTGDITHLSKASEFDLAAQLLSGMQ
ITELHTVPGEHDVTDGPGIEYFSRFGKPSNNKGYYSFDHNGVHFVGLVNVMHFKPNGLGS
LGDEQLEWLESDLKGRSSSTPVVVFAHMPMWTIYEPWGWGTGDAGQAMSYLKRFGSVTVL
NGHIHQIISKVEGNITFHTARSTAYPQPAAGNGPGPGPLTVASDQLPRMLGVTSVTIARH
PLKSTLADATLVS
>A0A3T2YK99|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Panama|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2K8Q3R1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter haemolyticus|TrEMBL
MIQITDTHLLEYPHLKFVGMQPEQSFHAVIDLMRQQHPQIDLIVHTGDLAQTPTPVTYNR
YIQHMQSLEIPFFHTPGNHDDVAHFPFHEVDQTQLTVIELGKWVIILLNSAQPQRIDGRI
TESQLKQLHTLLSKLHDRYVILACHHHPFAMQSAWIDQHKLKNASDLLETVKPFSNIKAI
VCGHVHQDAIHQWQGIEFLSTPSTCIQFKPKSEKFALDEEHPGYRYICLKANGELETQVY
RLKTSERMSSSEVLGYD
>A0A1Y1LGH2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photinus pyralis|TrEMBL
MIICTDENGKDNMESLDEQDGKEESNHSVLHRKSSLPLTPEDEPFDVYRSPPEIKYGLLI
PPNHSPLKLLVVCAHPDPVSEALSKAADKLGYDVTTCHSYEEALEEFLSKLHDLIVIDAR
YTSKALDYDTLCRSIRNTRGSQHTAAVALVKRSVFDKDDVTIMSLLDAGFNRCIAETTNI
VHFVNELIQIRHGDIRPLAQTAVNQSLYIALEKCSDIVLITDDSYRLQYVNRSSERFLGY
RYDELLGKSIHEQFIADPLQVTSMTSSLMRAREWQGSLLVRKKSQDTVSCNCKGIPIICA
GRVPTHFVLILDVHGITELTPTSYSLDKPRGSVQSNRRTSMDVRSVSSDYFRRTSLAKLS
ALPLEAPITKVISLLSQAQEQTNPNVVSIIDKVIEILNNTELYSPHLKDDLRLKCDEPVT
SDLITALLMQQPQIQLAPSSRRSSNDSTAVRNVSRGISKVRVPAQIKDLLDTSLTWEFDI
FRLEELTNKKPLIHLGMNLFLHFDVPATLNCDEKTLQNWLTVIEMNYHVDNFYHNSTHAA
DVMQATAGFLEKDRLKAIMDPLDEASSLIAACSHDVDHPGKSSAFLSNCDNPLAILYNDV
TVLENHHAALTFKLTLGDDRINIFKHLDRETYKVARHNVIDMILATEMTKHFEHLAKFVN
VFCQKTSRVDGESSDYIPITLPDNITLVKRMMIKCADVSNPTRPLRLCVEWARRIAEEYF
AQTDEEKSKGLPVVMPMFDRITCSIPKSQIGFVDYIVHDMFEAWDAFIDMPELVTYMRQN
YIRWKEFDEEGHNTSSDIRKLQNTILMAPAIIPKSSIKRSD
>A0A3R0B8G0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica I|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A403SNA1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella thompson|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A0P8M4X0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter freundii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYSRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A0A9W2W4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lygus hesperus|TrEMBL
MGCNHSRKATFKSISAQNLQTPDKKDKKEEKVKTPILNMKMVVGTVASNPDQLLPEMYES
LLKMESIQSSIALSKSVFAVLEKCRELVMITDNNNCIQYVNTPMARVLSHTPSELTGQIA
TVFQEHSDLQPAIRTLERGFEWVGRIRWRTKSGDSVSLQCRSMPISPAPSYPTYYLYLLD
SPSDCHFPRGSVPSLRKGSYDLKSIISEGSARRQSLAKLHNLPLEAPITKVLSLLCAAQE
NAPPNVIGMLEEVMDLLRTTELYTSHLKTDNLRAEDPLTTNLIAALVAKGPPSSIMPRRS
SAESPTKKKLMYKKNTNVVLPASKELKEAMKKINTWEFDVILVEKLTSGKPLVYVGIKIF
SIFNAYKVLGVDEKTLYSWLVLMENHYIPDNSYHNSTHAADVLQAAACFLLKLRSKKLLE
PLDEICCLIAAVAHDLGHPGKSSAFLTNAGDDLALLYNDISVLEQHHASLTFRLTLADDR
VNILRGLEQSKYSTARSCIIDTILATDMYKHFEHFTKFVTIYSKSSEDVPEKNEKPGESE
VDVNPEDVVVVKRMLIKCSDVANPTRPLQLCKHWAKRIAEEYFTQTDEEKERNLPVVMPL
FDRSTCSIPISQMGFMDYIVNNMFEEWDAFLEMPETLYNLRKNYDYWKDLNDKGCVGIEE
ETNGKKEVQDSAQI
>A0A3V4SJC2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Altona|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A4U2BV70|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. F13|TrEMBL
MELSHTSKFDESTIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGDN
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLPHGQFLPDFKAAGY
>A0A086EJW1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium brasiliense|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIQARQDAFDLIV
ATGDLAQDHTLQAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSAVLDRYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A0A2Y473|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Gallibacterium genomosp. 1|TrEMBL
MSDLFRDESAGVIKLLQVTDPHLFADEDGELLGINTFDSFRQVLSEIKKSGFESNYILAT
GDFVQDNSEAGYHRFVKEIVQLGKKIFWIPGNHDFQPKMEAVFDLYKAVIQPEKHLLLGE
SWQVILLDSQLYGVPHGMLSEEELKWLEQRLSLYPDRNTLIVLHHHLLPTNSAWLDQHNL
RNPYDFSEILAKHKNIKAIVYGHIHQEVNAVWQGIPVFATPSTCIQFKPDCAYFTLDNLQ
PGWREISLYPDGRLETKVHRIKDKVFLPKDNMNGY
>A0A3T2WB89|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Orion|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>Q8Z3P0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella typhi|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A6P8Y2D4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila albomicans|TrEMBL
MIISSPSQPANLSGTGTTSSTSPLSEESVESDCNCAGAATAAGVGAGTGTTALMMGRAAR
QMQTPAMEAATSTTSSTTATTPTTTAAAAAAITTTITSRASLTRPASESELLVGTGTSGT
SSSGGGRPGHRKSSLALALTPEDEPMDVYTRNLMDLKYPTVLPPNPQLKALLVFHKSDSI
CEVVTLACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSTKGLDAEHIARTI
RHTHGHHLTTIIAVCKKSFFEKDDALIALLDAGVNRCIAETTNLAMCSVELKQILHSIIR
PHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKPLADIFVS
DLSTISEQGKSIKEFDGILTVRRKNQEGIPMHVRVVPVACIGSAPTHLIFNFDIPGGGMD
FIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKIINLLSQ
VQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRRSS
NDSIIRTGNSTRTAIVPAKMKANPIVMELLEESLSWDFDIFKLEEITDYHPLLYLGMEMF
RRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADVMQATGAFITQLTNREMVM
DRMDEATALIAAAAHDVDHPGRSSAFLSNSNNPLAILYNDLTVLENHHAAITFKLTLGDD
KINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGSEVEPRELVQSEEETS
ILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRATCSI
PKSQIGFIEYIIQDMMHAWDSFIDMPQLITCMQINYSQWKKYDEQGVNTLADIMAKQPPV
GNKPSNSK
>A0A379JUD6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas oleovorans|TrEMBL
MPSLPTQSTDSSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIERVLQEQPQIDLILAT
GDLSQDGSEASYQRFRQLTSAIDAPTRWLAGNHDEIPPMQAACQGSELLEPVIDLGAWRI
VMLDSSIPGAVPGFLADGQLELLERALSEAPQRHHLICLHHHPVAIGCKWMEPIGLRNPD
ALFAVLDRYPQARTVLWGHIHQEFDQQRGNLRLLASPSTCVQFAPGSEEFQVSSEAPGYR
WLRLYADGTLDTGVSRVTGITFEIDYSVKGY
>A0A636X7K1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella dublin|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A2K9A2R5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. Pdp11|TrEMBL
MLKEAVSYSIAEGESVRIVQVTDPHLFADPEAQLLGVNTSKSFAAVLNTIRAVDYPAHLM
LATGDLSQDYSAESYQQFVKAVTPIGLPCHYLPGNHDDPRIMYLHMQGEQIFGQQRILAG
NWQILMLDSTVRGKPGGNMAETQFELIDKAIAAHPECHTLLVMHHNPIVVNCTWLDQHCM
DNGAEFIARVAKYPQVKGLLWGHVHQCIDTHHNGPHGSMQLMATPSTCIQFKPLSPYFAL
DSVQPGYRLLELRADGSINTKVYRVPGNHFSPDNNSSGY
>A0A7Y8APW1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas tolaasii|TrEMBL
MPSVSTVNPDAPALLVQLSDSHLFAEADGALLGMNTRESLQRVIERVREQQPQIDLVLAT
GDLSQDGTLASYQQFRDLTRQIDAPARWIPGNHDEPQIMAHAAVHSDLLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPNRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGRLETGVERVQNFAFTIDYGSNGY
>A0A6I9WYJ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pogonomyrmex barbatus|TrEMBL
MGCKISILKCMRGKVEQEESISSGISNSSSNTSDETETNRDQDSLYLAFNKHHFVVEEDD
REVAQCKTDAFDIVAEKNEKTPFEDSCAYDENGDYLTIKGPQDFSNYLLTTNVPSIIKIL
LVFSKDDQQMDILANAARRLGWSVSMAKDAEKAIELFQNRAHELVIIDHREHHAAEGDAI
CRAIRSSPVYHNSVIIALVKKSYFMLDEKDHIVALNLLETGFTRALMECSHEGILINELV
GIYTSSLLPKTQLAAAHALYLALDRCRDMVHITNDKNIVQFLNKVSEKLLGYKTEEMMGR
NLSEIVYYDNFALMEQQLSKGREFEGNMNCKRKNNQMITINCRIIPFCITLKKPSHYIYV
YDTTYLSENSAPISPVGSPLHPPLRPSVMPNTRKSSDVKSGISEGRRRSSLQKLHLEAPI
TKVITLLSNAVTDTTNPETAAQIDKAIDILKTTELYVPHLKEDKAMYSDPVATDLVGALL
ASPRTAWESRRSSSDSARLSTIKAITYPNSHVQKNFLGSQEITEILDKSLDWDFEIFKLE
VLTEKRPLVFLGLTIMNLYQVPTILHCDERTLQNWLAIIEHNYNAENSYHNSTHAADVLQ
ATARFMQSKKLKAILEPLDEVATLVAAAAHDIDHPGRSSQFLCNANNRLAILYNDLSVLE
SHHAALTFKLSLSDDSVNIFKNLERDAYKLLRQNVIDMILATEMTKHFEHLAKFMNVCSA
RIGEGQETYSDSLDMSVVLQPDNVILIKRMMIKCADVSNPTRPLKCCVEWARRIAEEYFN
QTDEEKKLKMPVIMPMFDRLTCSIPKSQIGFVDYIINDMIEAWDVFIDMPEIVGYMRHNY
EKWKEYNEQGISTLQDVEKLQQQHPEIQIP
>A0A1Q9NEF9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Heimdallarchaeota archaeon (strain LC_2)|TrEMBL
MKFVVFSDAHIGGKFNEETFIEGVKYINEIDADYYIFTGDLTDQGTVFEYELAKNKYLPM
IKKPVLLIPGNHDVKNVGDLLWEEYIGPRYFVHIDKTRKVKILGLDSNEPDQNTGRMGPK
AIERIYKEFEDLDDEWLKVLVFHHQTLPIKYTGRERSAVIDAGDAIKAIMDCNINLVLNG
HRHISNVYKLTDGDIKTLIVNCGTISCKKTRYHEEYSITTVEFDEEKLHAKIEVLLLKDN
TWVTKFDGDIVEHVIPDDFGELEATIIQIANTEISRGASFSTDIFTKGVQLINSIDCDLV
VHNGDITNRSYVREFNMARNYLGLIKHDMIVVPGPKDSFPLGKDLYEEYFGPTESEYTND
KMKILGINSCILDEKIGRIGRNTCKSILENLHSKNKINIIAFHHNIIPLPRTKHDSELQD
AGDVLSLIVNGKLNLVLTGAKNTSGCWQIDDTVFVNAGTLSSRSYNNRLGNSFNLIQVYR
TKKGRYYKITEFFFDIGESKVIGEFHIYD
>A0A369ZKL2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus parainfluenzae|TrEMBL
MNNTFECEPASEIVKLLQITDPHLFKDTSKDLLGINTHESFSQVLKEIQTESFDYDVVLA
TGDLVQDSSDEGYLRFVEMVKPLNKSVFWLPGNHDFQPKMVEHLSQSPINASKHLLLGKH
WQVILLDSQVSTAPHGELSAYQLDWLKMKLAENPARHSLVVLHHHLLPTNSAWLDQHNLR
NAHEFSEILSQFNNVKGILYGHIHQEVDGYWQGYQTMATPATCIQFKPDSNHFALDTLQP
GWREIELYPDGRIETRVKRIKHKTFLPNMEEEGY
>A0A8B7NX82|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hyalella azteca|TrEMBL
MRAMQAVFAALDSCRDAVHITDSNHRIQFINKSCETLLGYTANDVLGRSIWEVHGSDNHR
QEIKGNELKKQQSVSEEVKKQQNVTGEFKKQESISEEFINQQSVPEKLKKQQSVPGELKK
QQSVSGELKKQHSISGEIFNRDFEGKSEHLIKPWDSKVAELETLEESSNNGHRPVERQES
KVGLDISEAINLQLRRGREWEGVVVCRRKSGDLVQLPSKVVPVYTRRGSASGTSCDFVVY
SSCGISATVAPSGTFSSDVYHGRGSIKSVRKTSYDIRSMNSDGGPHNPARRQSLVKLHAM
TIEAPITRVISIITAAQENSPVYVSQALEKVLEILRSKELYSPQLVSSNEAPKSVSADPV
ATDLLGALLSHSPTPLTSGRRSSSDHGTRHQSTRPSLASLPQPAAGEIVELLATDNAWSF
DVLRLEQLTEKRPLVWLGLSLMCQMNVPATLNCDEQTLQNWLTLIEANYHSDNSYHNSTH
AADVLHATTYFLQRPRIAGLLDPLDVAASMIAAVVHDVDHPGKNSAFLCNTNNELAILYN
DTSVLESHHSALSFKLTHTDARVNIYNGLDRDTYKEVRKSVVDMVLATDMTKHFEHLSKF
VNMLDKCSMTRDENGQFETVGETLNVAQLSTVENQQIMRRMLIKCADISNPLRPLNLCRE
WGHRIANEYFSQTQEEKRLNLPIVMPQFDRATCSIPKSQIGFIDFFISDMFEAWDALADI
PECMAHLRSNYDYWQERQREEQECQSANCPPSGGTATTPLKEEEEELEPLDPRTTPDKKE
>A0A1B8T3I8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus parainfluenzae|TrEMBL
MNNRFEYEPASEVVKLLQITDPHLFKDTSKDLLGINTHESFSQVLKEIQLESFEYDVVLA
TGDLVQDSSDEGYLRFVEMVKPLNKWVFWLPGNHDFQPKMAEHLSQSPINASKHLLLGKH
WQVILLDSQLSGVPHGELSTYQLDWLKTKLAENPARHSLVVLHHHLLPTNSAWLDQHNLR
NAHEFSVVLAQFNNVKGILYGHIHQEVDGYWQGYQTMATPATCIQFKPDSNHFALDTLQP
GWREIELHPDGRIETRVKRIKQKTFLPNMEEEGY
>A0A2R8BZ44|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Palleronia abyssalis|TrEMBL
MKILFVSDLHLDHWLMAGRDPLAAVPQSVWDQVEALFIIGDLSNKPKVRWPPLLEHVGRY
VPLDRVFITPGNHDYYDFQLDGDDRLAEIATEAGASFAQKAEVMLGGCRILCCTLWTDFA
LAGHREATRAAMMAEAEAQINDYRYIRIGGEGYRRARPADTARRHADHRAWLEGKLAEPF
DGNTIVATHHAPHPECLAPPVSRLDAAYASDLTSLIDAHAPTAWVYGHTHMPCAFTVGAS
ELRNVSLGYPHQVPETEIAAQLLQGLAKVERGRVALKSSSDRRSDLDAEA
>A0A427FRQ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. o96-267|TrEMBL
MPSLPAPSTESSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIERVQQEQPQIDLILAT
GDLSQDGSVASYQRFRQLTSAIAAPARWLAGNHDETPPMQAACKDSELLEPVIDLGAWRI
VMLDSSIPGAVPGFLADSQLELLERALSEAPQRHHLICLHHHPVSIGCKWMEPIGLRNAD
ALFAILDRYTQARGVLWGHIHQEFDQIHDNLRLLASPSTCVQFAPGSEEFQVGNDAPGYR
WLRLHADGKLDTGVSRVTGIDFEVDYSVKGY
>A0A446CV07|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Achromobacter agilis|TrEMBL
MLIAQITDLHMRTPGNKAYGIIDPAAFLAPAVRALNALTPRPDCVLITGDLTDLGKPEEY
EALRTYLEALEIPYFLLPGNHDDRAQLRAAFPDHGYLQGQGPFIQYAVETYPLRLLALDT
VVPMKSHGELCQDRLDWLAARLAEQPERPTLVLMHHPPFLTGIEHMDAIGLLAGAPELER
IVARFPNVQRVLCGHLHRTIFQRFGGTIASTCPGTAHQLALELGPRPTLQYIMEPPGYQL
HWWHGGNLVTHHAVIGDYPGPYPFA
>A0A4Y7XD53|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Alkanindiges illinoisensis|TrEMBL
MIYQVEIPASVLSQERPLRLVQCSDMHLFADPATKLLGLNTQHSFQSVIELIQQQQPNID
LLLTTGDIAQQSSPETYQRFLATMQPLRAPHFCIPGNHDLDEAYHSGLRINQLPCEVIIG
NWCCILLDSTVDHEIAGSFSNSTLEYLQQALERQRNRHVLIALHHNPIAVGCEWLDQHML
KASQTFFDIIQPFNNVKLVIHGHVHQRFEQVYEQVSYLSCPSTSLQFKPRSAKFTLDTVN
PGYRWLDLYANGYFETDVCRVENFNFYIDYQSNGY
>A0A1S9JNU1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shigella boydii|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGMLTTEVHRLADTRFQPDTASEGY
>A0A7X9TUG5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. SWRI 103|TrEMBL
MPSVSAVSPDAPVLLVQLSDSHLFAEADGALLGMNTRESLQRVIELVCAQQPWIDLILAT
GDLSQDGTLESYRQFRDMTAPLGAPTRWIPGNHDEPPIMAQAAAHSDLLEPVVDIGHWRV
TLLDSAVPGSVPGYLQDQQLQLLVQALSEAPNRHHLVCLHHHPVSIGCAWMEPIGLRNPD
ALFAVLDRFPQVQAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFMVSGQAPGYR
WLRLHADGRLETGVERVQDFVFTPDYGSSGY
>A0A2H5VN95|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR08|TrEMBL
MPWIVRMLLLLGASLLILYGYVIWRLAWALAQRTGRSAQHWRKRLWPIAALLTLYPAVAI
GGYLLDAPFWRTALRNGHPLVDALLTYPFWIGLLVALQLFVIFLLLDGGRALARLWTKSA
DRGIARAMLGLTLIVLVYTPIRAYRDTRQIRLREQVITSEKLPADIEELRVVHISDLQLD
ARTEAALVQRFIERVNALRPDLVFFTGDLVTSGTEYIEPAAAGLGAVRARHGVYACLGDH
DYWADPRRVPESLRRHGIVLLDDASRSISVGNASLHLTGVTNIYRRRPSPETLARLAEEK
PAGRFSILMAHQPSPSLVQWAKAQDYDLFLAGHTHGGQIVLPFFGLRLALARLETPYVSG
AYDVGSLWVNVTNGLGLTFAPLRFHAPAEIVLLRLMPLKAGSLR
>A0A2H5WGS2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR13|TrEMBL
MKWFIITFFSLYSLMHLYVFLRMIRPNFSTQKSLAFVLLFFIMILSPVLWRTMEGNVSKN
LVYLVALISLLWMGFMLYLFIFSFLLDAYRALVFLSKHLLGINPLPVPSPKASLYLVLFL
SISLSAYSYYETLRLEVIRIKIQTEKLPVDRIKILHISDMHLGPVMGADKIELVKEVWER
EKPDLIVSTGDLVDGNMRGKDGLADMLKLMTAPLGKYAVLGNHEYYRGVDQALEFTERAG
FEILRGEWKDLGSLVVVGVDDDDCRFFNACKGELSEHYLLKQVPHEKFVILLKHKPKLDP
EAVGLFDLMLSGHTHGGVYKPVGEFILKKLFITDRGLVKLGSSYIYVSKGVGTGGPPMRL
FSPPDVAVIEIISSGKPSSSQGTPLQKRQREDEAQRAYF
>A0KT47|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. (strain ANA-3)|TrEMBL
MLKEAVSYSIAEEESVRIVQVTDPHLFADPEAQLLGVNTSKSFAAVLNTIRAVDYPAHLM
LATGDLSQDYSPESYRQFVAAVAPLNLPCHYLPGNHDDPRIMYLHMQGERIFGQQRILAG
KWQILMLDSTVRGKPGGNMAESQFELIEQAIAAHPDRHTLLVMHHNPILVNCAWLDQHCM
DNGTEFLRRVAQYPQVKGLLWGHVHQQLDTDYDGPHGPLQLMATPSTCIQFKPQSPYFAL
DGLQPGYRLLELKADGSICTNVYRVPGNLFSPDKDSSGY
>J5W5D4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella sp. OBRC7|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFTAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQVLLMDSQVFGVPHGELSDFQLEWLEQKLTEVPQRYTLLLLHHHPMPSGCSWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A6B8N9D2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. THAF191c|TrEMBL
MKVTSCSSDGSIRLLQITDTHLFEATDGSLLSVNTADSFNAVVDAIVEESPAYDAVLATG
DISQDHSEVSYQRFEQGIVPLKKKCFWLPGNHDFKPSMNSVIPSQQIQQIDHVLLGDTWQ
MIMLDSQVVGVPHGRLSDKQLNLLEEKLSQYPERYTLILLHHHPLLVGSVWLDQHTLKDS
DDFWQVVDQHNNVKAVLCGHVHQDMNVMRNDVRVMATPSTCVQFKPNSDDFALDYQSPGW
RELLLRDNGEVETQVKRLPAGCFQPDFNSAGY
>A0A8B7LUC5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila elegans|TrEMBL
MGCSPSTLPAPSATAGQTDGPGSLPLDASEKDGSRLFCIKLRRSRLRRCSCGGVTLQPPS
DGNGSSTGDNLCGQVLLNPLQTKSEADYEKLSTGKKDSIVTVAALGNFTHSVVRRATGST
GTSGTSSSGGGNSRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLV
FHKSDSICEAITAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIIIDARSTKNLDA
EHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQ
ILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLLNMRLDEIISKQ
LEDIFVSDLSTISEQCKNIKEFDGILTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFD
VPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITK
ENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPSVYSSRRSSND
SIIRTGSSTRTATIVPAKMKSNPIIMELLDESLSWDFDIFKLEEITDYHPLLYLGMEMFR
RFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDMLVM
DRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLGDD
KINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPREHNSQTDEETS
ILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRATCSI
PKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGVNTLAEIMAKQPPV
GKMANSK
>A0A6P8WHE8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila albomicans|TrEMBL
MRNCLPKIASVFRIKSSSAAAHSNESDEDSDTDRYIRAKPTATTTTTTTATAAATTTTST
TITSAVTTESDQLLDNGNKKPQQQQQQQQRSAAKATTTTTTKTADDVDKNRLISDVSTAN
TNSNGWDLEQSHKESNASITNGSIRQRQRQWQQQQQQQVYDKNLDTEMKVPGVEISLATP
VPAMPMPSHGRLSNSSKTPEQMELEYEANVAAERGDIMTPLPRDPRPQGMTFPGDAAAGV
GMGNSSVGGGRNMQPEIVEAIRNLDAQALRLNNLTLEDRCQLTTQQENKPDDDTDYVVLR
RPQKHHPFDRQCHSLYERRLYKGPKLHLWVGNGKKPSPSDDDDLKTFQRNLMDLKYPTVL
PPNPQLKALLVFHKSDSICEVVTLACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLII
IDARSTKGLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDALIALLDAGVNRCIAETT
NLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQYANRATERLL
NMRLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMHVRVVPVACIG
SAPTHLIFNFDIPGGGMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKL
TSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATD
LIGALLTGPSVYSSRRSSNDSIIRTGNSTRTAIVPAKMKANPIVMELLEESLSWDFDIFK
LEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADV
MQATGAFITQLTNREMVMDRMDEATALIAAAAHDVDHPGRSSAFLSNSNNPLAILYNDLT
VLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSV
FGSEVEPRELVQSEEETSILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYFMQTDEEK
QRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWDSFIDMPQLITCMQINYSQWKKY
DEQGVNTLADIMAKQPPVGNKPSNSK
>A0A6N4X7H9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chryseobacterium potabilaquae|TrEMBL
MNLSLKTSFKKKSVPFRIILSAVLLYSCATYNVKKGKNLYEVNDIKSENKFKIFLVGDAG
NADEIQAQHTLKFLKNKLDSADSNSMLIFLGDNIYPLGMPKDTDEEYPLAKKKLENQLII
TQNFKGKTLIIPGNHDWYHGLEGLKAQEDFVKNYFNDKKAFLPKGSCPIDDINLTKDIKL
IVIDSEWALINWNQFPGINKNCTIKTREDFFTEFKDLINKNQDKRIIVALHHPVISTGTH
AGYNSVKSHLYPLKSKFPAPGFASALNILRSSSGASIEDINNQHYADLAKRLKSIVQDKE
NIIFVSGHDHNLQYHEDRNIKQIISGAGSKTDPSTIAEHTDFSYGGSGFAILNMRKDEST
DVEFFSTKNNQFKRLSHIQVIEKPKEFINPYPNSFPKTFSSTIYPKKLTEKGKFYKWLWG
EHYRYYYGIPIEAPTANLSELDGGYIPFREGGGNQSNSLRLKAQDGQEFVMRGVKKSAVR
FLNNMAFKKSTFGDELKNTFPEKFLLDFYTTNHPFTSFSVGNLADKIHIFHSNPRLFYIP
KQSALGEYNDKYGNEMYMIEERFSSDSKTLKALDNAQDILSTDDILKNFTKNYKYSIDKE
SYIRARIFDMFIGDWDRHSDQWKWAEYHQGDKIIYKPIARDRDQAFSKYDGAAFKIIMNI
PAIRHMKTFKDDIKNVKWVNMEPYPLDLVFLKGSEEKDWIEQAKFIQEHISDQDIENAFK
NLPKEVQDETLADIKRKLKSRRLKLQDYATRYYDVLQEKVPLAGTTNPDQFTITKTGNSV
NVKQYKLGKNKENPELVFEKTYYDTKTKELWIYGLEDDDLYEVLGDGKPKINIRLIGGYD
HDVYNVKNGSKVKIYDFKSQKNTYNAPSATKNISDDYNINTYNYKHPKYNYFAGYPNIDY
NPDDGLILGFLANYTVNNFIRDPYSQKHSLKGNFYSATAGFNLIYKGIFKKAIWGLDFNI
DAAYTTPRFSENFFGLSNESQYYKEGTQRRYNRARISKFSFAPSISKKSWMNLQHQFQLS
FEKNKVQRKDNRFVDISPDVRPEVFTNQQFAGANYTFSYKNLDNVAFPTLGMEFMVNADW
KANLSNFNKNFLTLSGALTIDHRLDKRGNFVLANSSNAMWISNTNFEFYQAASIGGNNGM
RAFRNERFSGRSYFTNNSEIRWDFGRVRNNIVPANMGILLGYDVGRVWNNNENSRKWHQS
VGVGFWMSIVEMFSARLNYFQGTDGGRISAGVGMTF
>A0A5J4RCM7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MKFFPIISASLLILGANFYVFYRLWVMLPASIVGRVLLVTFGVVALSSFVLVQVIGNNLP
LSLAALMYRVGTSWFFIFIYLLILFLLLELVRVTGLFPVVKFMHGSWYGLGMLAGALTLI
LTGGYIVYLHKARVELSLTVNKEVGAERSLKIVAISDLHLGYGIGRKEFESWVKLINKEN
PDIVLIAGDAIDNSVRPLYERGIAESFKQINTKYGIYASPGNHEYIAGISNSLAFLKEAG
ITVLRDSVAFINDTFYIVGRDDRANSARKSVEELTDTLDKSKLLILLDHQPYHLEQAERN
GIDFQISGHTHHGQIFPISWITEMMYEKAHGYLKKGDSHIYVSSGLGLWGGKFRIGTRSE
YVVIHLKPLKTL
>A0A5J4RWR3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MNILFFSDTHRLHRRLKNLPPADMIIHAGDISFSGEDHEAEDFIRWFGKLDYKYKIFIAG
NHDFYFEDETIRRIQQMLPGNAYYLCDSGVEIEGIKCWGSPITPLFNWAFNCERGEQICG
HWKLIPKDTDILITHTPPLGILDRTTRGIHTGCEDLLKTVKRITPRYHLFGHIHEAYGMI
QSGETTFINGSVLDKNYYIKNKPVIFCYEKELMH
>A0A5J4PED8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|termite gut metagenome|TrEMBL
MIKLFPIISVLLLILGANFYVFYKLWVMLPAGIIGKVSLVTLGVAMLFSLV
>A0A8G0CC08|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cholerae|TrEMBL
MSSQSEDSSIKLIQITDTHLFAAEDGCLLSVNTADSFAAVVATIGEEQVEFDAILATGDI
SQDHTPESYQRFVRGIQPLQKVCYWLPGNHDYKPSMHSVLPTQQIQAVEHVLLGEHWQVV
LLDSQVVGVPHGKLSEQQLQLLDSKLTEYPELHTLVLLHHHPLLVGSAWLDQHTLKESER
FWDVVAKHSNVKAILCGHVHQDMDRIHLGARVMATPSTCVQFKPNSQDFALDNCSPGWRE
LTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A1B8QPF4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus sp. CCUG 66565|TrEMBL
MKNTFVYQTEKSIIKLLQITDPHLFKEKETALLGVNTQASFTQVLKEIQQENNTFDIILA
TGDLVQDGSDEGYRRFVEMVTPLNKPIFWIPGNHDFQPKMVEHLNKTPIESAKHLLLGKY
WQALLLDSQVYGVPHGQLSQHQLNLLEEKLAQHPNRYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLGKFSNVKGILYGHIHQEVNALWNGYQVMATPATSIQFKPDSHHFTLDNLQP
GWREIELHENGSIYTQVKRIQEAQFLPNMQEEGY
>A0A8B9FV85|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Amazona collaria|TrEMBL
YFQNSYVNDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMS
RNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKAS
LTGKN
>A0A7Y4XUM1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methylococcaceae bacterium|TrEMBL
MPPAGSPLTVLQLTDTHFLAEAGQKMLGIDTEYYFVQVLGQALADNQQVDLIILSGDLAQ
DPCPGSYQRLQQHLAKISVPVLCLPGNHDDFELMQTLLNVNNSSCAKQHLFEHWQIICLN
SQIPDEPGGYLAASELTLLKQALEDYPQHHALIAMHHHCVPTNSMWMDTMLIGNSVDFLT
ILQNYHQAKVIITGHIHQELTQQIQHLQILSAPSTCFQFTPNSRNFSIDKTAPGYRKLLL
YPDGSLISSVSRLPITLNELNLDGRGYLIDNH
>A0A327Q2I0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas salmonicida|TrEMBL
MRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQVNENPFDLILATGDLSQDHSPESY
QRFASMMAPLARPIYWLPGNHDDGPLMTEYLHAAGISEAKQLVGEHWQVMLLDTQVRGKP
HGVLGDHQLAALDSALRQHPERHALIALHHQAVPVGCAWLDQHNLKNADDLFAVLARHPQ
QKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLSDGFALDESGPGWRYLTLHPDGRVA
SQVWRLPVGQFVPDPDATGY
>A0A385ZEE4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces griseorubiginosus|TrEMBL
MCTSHEHDHGQEAPQAGAGRRSFLRATALLGAAAGAAVTLPAVAEAAPASVAGHRPDPDS
RRFTLAVMPDTQYLFDGPSIDKAPVEASLRYLLEHGKDENIVFLSHLGDLTQNGAAPEFA
AISEAFELLDRRGVGYSVLAGNHDVKSSSTDQRGATPYLDAFGPSRFERHRTFGGASADG
YNTYHLFRAAGREWLVLALDWRLSDQGYAWARSVLAAHPKTPVILTTHELVVEDDTLSDY
GQQLWDRLVKDHDQIFLTLNGHYWPAGRATRKNSAGNDVHLHLTNYQNRYFGGAAMIRLY
RFDLDRGVIDVETVSPWILGRAGKGLNALERQEIELSGDADRFTVGIDFAERFSGFAPVP
ARAARPASKMLLPGTAAYWRFDSAVSGTVRDLSGRGNDLTVVSVGGGTLGWSADHHPDQP
GHGSLEFRGWKSPLKGAYLRTVDGAPLNSAEFKDGYTIEVFYRMPADWDPDHNAWAGLVS
RQGTGGAAGKTGDDPDEPLATLSLSNDREPQWAMRPLNQQGIATNWGQETPLETWWHLAV
VNDGRHTTLYVQGCPVVRNPKASAVGITSVGEPWLLGGYTYADKIDQIFHGRLGDVRIVS
RALPVSSFMTH
>A0A385ZMC4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces griseorubiginosus|TrEMBL
MARVPAAARKILSAVRKAPHALTRQYAGRRSHPSVELVHPAHPWTRALGLVAVVLLGAWL
GLLIVGNVRVPVGPMNTTMTLRPSLTGGTKINVSPLGALELDSHHAPVRLDVNVDQLDPE
RSQALVDHPERLSGLQDEVASDVEHGTLDLAVRSCVAVVAGATALGLAVYRRPRRALAAG
GLALTLLAASGGTAYATWNPESVLEPKFSGLLSSAPSLVGNARSIVTEFDVYQKELARLV
TNVTKLYDVTSTLPAYQPDPTTIRVLHVSDIHLNPASWKIIASLVEQYKVNVIVDSGDTM
DHGTAAENGFLDPIPDLGAPYVWVRGNHDSLTTQRYMEGLKRVHVLDDGKAETVAGLRFA
GMGDPQFTPDRSTNPGTDASEEAAGARLAAALRAQRAAGTPVDIAIAHEPSAAREVDGEV
PMILSGHLHHQEMEVLKKGTRLRVEGSTGGSGLRAVEGKYPDPIEASILYLDRDTRRLQA
WDEIKLGGLGLTTAEVSRHLPQDNQPGARPSPSPSESSSGSPSPSPTGSP
>A0A806GA41|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aggregatibacter actinomycetemcomitans ANH9381|TrEMBL
MLNTYKYDTRQEVFRVIQITDPHLFKDATGELLGVNTQESFSQVLSEIRQQPYDYDLVLA
TGDLVQDSSEEGYLRFCESVKPLEKTVFWIPGNHDFQPKMFDILKRDNICDKKHILLGEN
WQILLLDSQIAGVPHGQLGQYQLDWLMAKLKEHPQRYSLVVLHHHILSTHSAWLDQHNLR
NAHELAYTLAPFNNVKGILYGHIHQQVDGEWNGYKIMATPSTGIQFKPDSNTFALDTAQP
GWREIELYADGRIETRVKRIQHKTFLPNLQEEGY
>A0A2P1VQB0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Plesiomonas shigelloides|TrEMBL
MESLFQPPVATERVRLLQITDTHLFADEEGALLGINTLQSYHAVLDAIVAEQQIAEQQPV
DLIVATGDLAQDHSLEAYDRFADGISRLDSPCVWLPGNHDFQPAMVDGLRGKGIQPSKQV
LLGDHWQLILLDSQVLGVPHGELSDYQLNWLAARLDAHPKRHAAILLHHHPLPSGCTWLD
QHSLRNSHVLDEVLSSRPQAKVVLCGHIHQEMDLNWNGRRLLATPSTCIQFKAHCTNFTL
DQLTPGWRYLDLLPDGRVETQVHRLTDQRFSPDMESEGY
>A0A1X3S3C0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lonsdalea britannica|TrEMBL
MESLLTLPVARGARVRILQITDTHLFAGKQETLLGVDTYRSYHTVLEAIATRQYDVDLIT
ATGDLAQDHSLTAYEHFAEGIRRFDAPCVWLPGNHDFQPAMVDALALAGIAPSKHVLLGE
HWQVILLDSQVFGVPHGELSEYQLEWLERILSSHPERFTLLMLHHHPLPSGCTWLDQHSL
RNAHSLDAVLSRYPNVNTVLCGHIHQELDLDWHGRRLLATPSTCVQFKPHCTNFTIDSVA
PGWRYLELLPDGGVETQVVRLEGNAFLPDMDSDGY
>A0A2J8S135|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pongo abelii|TrEMBL
ETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVS
EYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGVKKLMHS
NSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQAVFT
DLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNC
DIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKT
>A0A1A8JE61|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothobranchius kuhntae|TrEMBL
MLKRSWSAQGGTPSDENPDPLVGQFSSGCTLGVEACKVHRRFSGNLQLPPLSWRQAETER
DRGRPLTPEEDPVTRSRPTSLPIVSLPRIDITQADSDSLEVENAPPLCCSPSDLQASPGS
GLVLHPNMANHGQRRESFLYRSDSDYELSPKSLSRNSSIVGELHSEDLIVTPFAQVLASL
RTVRNNFTTLTNVQCASTKRSPAANQPCVTKVCLSDESYQKLAMETMEELDWCLDQLETI
QTYRSVSEMASNKFKRILNRELSHLSEMSRSGNQVSEYISNTFLDKQNDLELPCPVQKSR
ERKRRQG
>A0A381CBZ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Buttiauxella agrestis|TrEMBL
MESLLNLPVAGGGQIRILQITDTHLFSGKDETLLGINTWMSYQAVIDAILAEQRHYDLIV
ATGDLAQDHSAEAYQHFVEGIAEILAPCVWLPGNHDFQPAMFSSLLEAGISPAKQVFLGD
SWQILMLDSQVFGVPHGELSDYQLDWLERKLAGAPERHTLLLLHHHPVPAGCSWLDQHSL
RNAAELDNVLQKFPKVKTLVCGHIHQELDLDWNGRRMLATPSTCVQFKPHCANFTLDTIE
PGWRWLELHPNGEVTTEVCRLKGAVFNPDTASEGY
>A0A2N7CSD0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. 10N.286.51.B7|TrEMBL
MLKEPVSYSIADTDVVRLIQVTDPHLFADPEAKLLGVNTAASFQAVLDTFLATEYPADMV
LATGDISQDYSPQSYQHFSSTIAKLDLPCHYLPGNHDDPRLMSLHMQGHHLFGQQRIIAG
EWQILMLDSTVRGKPGGYMAEQQMALIDEAIAAEPNKHVLLVMHHNPILVECSWLDQHCM
ANGEDFLKRVSRYSQVKGALWGHVHQTIDSQYSTAEGGIHLMATPSTCIQFKPKSSYFAL
DGLQPGYRLLELASNGSIQTNVYRVPGEKFSPDNDASGY
>A0A5B0VB64|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter salinexigens|TrEMBL
MTIKADSRPLRVLQLTDPHLMADPGGALLGVNTRDSLSAVISEVLDVHGQPDLILATGDL
AQDGSEEAYRVFGEQLQVFGCQSAWISGNHDRSDILHRVATRFQADQRQIVQGGWQFVLL
DSSVSGKVFGELAPSELDFLERCLSQHPGTPTIVSLHHHPVDIGSDWMEKIGLQNREAFW
HVIDQHPQVKIVLWGHIHQDLEQQRRGVSLLATPSTCIQFTAGSSDFSVEPLPPGYRWFE
LGPGGEIHTEVRRAHRFEFTLDQNSSGY
>A0A7G9YPQ9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methanosarcinales archaeon ANME-2c ERB4|TrEMBL
MRLLAISDPHGDYTQVPLLVREAERTGSIDAALVAGDITNFGPDELAYELLDLIEPLGCP
VLAIPGNCDQRSILATLDASKAVNLDGAVHTIENVTFAGIGGSNPTPFDTPFERSEDEIG
AMLEDLLIRADRGGGTIVLLSHAPPKNTLDRIPGGNAGSDALARAIGKVDLIVCGHIHEG
QGEMTRQGTRIVNVGQASQGQSVILTIDESIEVQFNNI
>A0A6P3WMU6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Dinoponera quadriceps|TrEMBL
MGCKTSILECMRDKVELEKSTSSETRSSLVTSDVTETDKEQSSPYLMFCERRLVTEEDDH
KEQPQHKTDVLDIVGEKTPFEDNAHDDSDYLTIKGPQDVNAHLLTTSVPSIVKILLVFSK
DDQQMEILATTASKLGWSVSVAKDAEKAIELYQNRAHELVIIDHRGHRAAEGDAICRALR
SSPVHYNSVIIALVKKSYFMLADKDHIAALNLLETGFSRAMMECSHEGILINELVGIYTS
SLLPRTQLAAAHALYLALDRCRDMVHVTNDKNIVQFLNKVSEKLLGYTLEEMMGRNLSEI
VFYENFALMEQQLSKGREFEGNMNCKRKNNQIITINCRIIPFCTTLKKPTHYIYVYDTTY
LSENIAPISPIASPLHPPLRTSILSNARKHSDVRSAISEGRRRSSLQKLHTLQLEAPITK
VITLLSNAVTDTTNTETAAQIDKAIDILKTTELYVPHLKEDKIYNDPVATDLVGALLSQS
SRTWDSRRSSADSARLSTIKPAMGPTNARISMKNFRGPQEIADILDSSLEWEFEIFKLEV
LTEGRPLVFLGLTIMNLYQVPAKLNCDEKVMQNWLSIIEYNYISENSYHNSTHAADVMQA
TATFMQSKRLKEILEPLDEVAALIAAAAHDIDHPGRSSQFLCNANNRLAILYNDLSVLES
HHAALTFKLSLSDDSVNIFKNLDRETYKLLRQNVIDMILATEMTKHFEHLAKFMNVCSAR
IGDGQVESYANSLDMSVVLQPDNVILIKRMMIKCADVSNPTRPLKSCVEWARRIAEEYFC
QTDEEKKLKMPVVMPMFDRQTCSIPKSQIGFVDFIINDMIEAWDAFIDMPEMVGYMRQNY
EKWKEYNEQGISTLQDVEKIQQHPDLHIPRLPR
>Q0HYP9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. (strain MR-7)|TrEMBL
MLKEAVSYSIAEEESVRIVQVTDPHLFADPEAQLLGVNTSKSFAAVLNTIRAVNYPAHLM
LATGDLSQDYSPESYRQFVAAVAPLNLPCHYLPGNHDDPRIMFLHMQGERIFGQQRILAG
KWQILMLDSTVRGKPGGNMAESQFELIEQAIAAHPDRHTLLVMHHNPILVNCAWLDQHCM
DNGTEFLRRVAQYPQVKGLLWGHVHQQLDTDYDGPHGALQLMATPSTCIQFKPQSPYFAL
DGLQPGYRLLELKADGSICTNVYRVPGNLFSPDKDSSGY
>A0A6Y4C2I3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella typhimurium|TrEMBL
MFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSLRNAGELDSVL
ANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIAPGWRTLELRA
NGVLETEVHRLQDTRFRPDTASEGY
>A0A6L6GC82|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. YIM 103518|TrEMBL
MALTENNKQNDLTVIQISDTHLMNKDNLEFLQMNPSATFHAVMKDLQQKYPHVNSIFHTG
DLAQAPVPETYETYINFMNSLGIPYYQIPGNHDKAEFFPFHHNQNQVHAIKIGFWTVILL
NSAVKGQVHGWIEDEQLQQLDTLLAEHKDQHIIITCHHHPLEMDSRWIDNHKLKNSESFC
EIFKKYSNIKMVLFGHVHQESINLWNNIHFYSTPSTCVQFKPKSEQFALDSSAPGYRVLH
LKEDGTFSTEIHRIDTLNLKINLEISGY
>A0A0J1LT42|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. MGH105|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRARYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>L5M0I6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Myotis davidii|TrEMBL
MSPCKYSLQCHFFSFLYSFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYR
SDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNMQDRAPSKR
SPMCNQPSINKATITGKKDLGAHSSHVEEETIFPNIQHNMNTDFIQHL
>A0A0K9USH8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio cholerae 2740-80|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFAAEDGSLLSVNTADSFAAVVAAIGEEQVEFDAILATG
DISQDHTPESYQRFVRGIQPLKKACYWLPGNHDYKPSMHSVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEYPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRIHLGARVMATPSTCVQFKPNSQDFALDNCSPGW
RELTLHADGQVSTQVKRLKQGRFLPDFNSNGY
>A0A5I8I0U2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Ouakam|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A5L5A7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrionales bacterium (strain SWAT-3)|TrEMBL
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDGIVSQGFDYQAILA
TGDISQDHSAESYQKFESGIQPLEKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLDER
WQMIMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
DADQFWDVVQQHSNVKAVLCGHVHQDMNREHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGTVSTQVRRLSHGQFLPDFKAAGY
>A0A659LCD0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. E2586|TrEMBL
MESLLTLPLAGESRVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISSAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLVKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADSRFQPDTASEGY
>A0A6I1YRB9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptomyces sp. RB17|TrEMBL
MSRIRSVAASALEVNRRTVLAAAGAVSLSAGVGYALRPTDSQAATTAAAPVAHSRQAPAA
APLAPYTKGTTLASVAAPLGSSGYRRLGDGAGWSRVVRGELAAPKSGRAGRRTALAAFVQ
FTDLHLQDVQHPLRLEYLRSHDAHAWRPHEALTVPGAISLVERVNALRGAPVTGAPLHFV
MTTGDNTDNNAHSELEWFMKVMSGGRITPNSGDPKHYEGVQNSGLKLYWQPDSTLRDGDK
ALGFPQLKGFLAAAVREVQSPGLKLPWYSTVGNHDALPLGCYGSHGDPYLAEAAIGGKKL
FSVSDADARKLQDAIKNATDPKAAGYRDFLKAHARSMRSVTPDEKRAPYTQADYLKAHLD
PAHQGLGPVGHGYSSANLDAGTQYYAFRISDDVIGISLDTTDAGGHYEGSIGTAQLNWLD
KTLKDNKDSYAVVFSHHTSKTMDNTRPDPARPGEKRHGGAEVISVLSAHANVLAWVNGHI
HKNVITPHQASGGRSFWEISTASHVDYPHLARIIELVDNKDGTISLFTTLIESAAPHRTD
FADLSQTGLAALYRELAYNAPGANKTLAGSAADRNTELVLKKG
>A0A6P4LKB4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila bipectinata|TrEMBL
MGCSPSTLPAPSSTSAAAGGQPTSGQGSLPPLDASEKDGSRLFCIKLRRSRLRRCSCGGV
TLQTPNDGNGSTAGSGAGDNLCGQVLLNPLQTKNEADYEKLSTGKKDSIVTVAALGNFTH
SVVRRATGSTGTSGTSSSGGGNSRPGHRKSSLAFALTPEDEPMDVYQRNLMDLKYPTVLP
PNPQLKALLVFYKADSICEAVSAACQRHQLDVTLVKSKEEALDTLQKSYATAQCYHLIII
DARSSKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCVAETTN
LAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLN
MRLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMHVRVVPVACIGS
APTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLT
SLPLEAPITKENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLIGALLTGPS
VYSSRRSSNDSIIRTGSSTRTATIVPAKMKANPIIMELLDESLSWDFDIFKLEEITDYHP
LLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADVMQATGAFIT
QLTNRDMMVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDSLAVLYNDLTVLENHHAA
ITFKLTLGDDKINIFKNLDKEQYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGDESRE
PHAQTEEETSILMRRMLIKVADVSNPARPMQYCIEWARRIAEEYFMQTDEEKQRHMPIVM
PMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKYDEQGINTL
ADIMAKQPPVGKLANSK
>A0A1V3J3M6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rodentibacter genomosp. 1|TrEMBL
MRNTFVYRSGKPIVKLLQITDSHLFKDENNELLGVNTQTSFAQVLKEIQQENTEFDVILA
TGDLVQDSSDEGYQRFVNMVKPFGLPVFWIPGNHDFQPKMVENLNQPPMEKAKHILLGEY
WQVLLLDSQVYGVAHGELSRYQLDLLKTTLEKYPDRHTLIVFHHHVLPTNSAWLDQHNLR
NSHELFDVLAPFKNVKGILYGHIHQQVDSCWQGYKVMATPSTCIQFKADSQHFALDDAQP
GWREIELHSDGVIVTNVKRIRQAVFLPNMQEEGY
>A0A3V8VN47|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Agama|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDVDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A365VZP0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. MWU12-2534b|TrEMBL
MPSVSALTADDSVLLVQLSDSHLFAETDGALLGMNTADSLQRVIDLVLAQQPRIDLMLAT
GDLSQDGTLESYQRFRQLTRQIPAPGRWLPGNHDEPQVMQLATGDSDLLQPIIDIGNWRI
TLLDSAVPGSVPGYLRDDQLQLLARSLGEAPERHHLICLHHHPVSIDCAWMEPIGLRNAE
ALFAVLDRFPQVRALLWGHVHQEIDRLRGDVRLLASPSTCIQFEPGSDDFKVEEQVPGYR
WLRLLPDGRLETGVERVHGYVFSIDYGSNGY
>A0A2J7QT88|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cryptotermes secundus|TrEMBL
LCFRHGRRGTLDLENGNSSQKNQQTTGTPGGFSITNQDCTTKVLLAFGKEDFQSDAFWLA
CEKLGYECNLARTRDSVLEAFQTKSHEIVIIDTRNPKVIDGESLCRALRALKTSQYTVVV
GVVRKGTSEKEDSSIEPMLNMGFNRVIMETSGLVQCMNELLQLYLSDVQPRLQLATAQAM
HIALDKCSDVVHITDQNLNIQYMNRSSERFLGFSMKDVAGKSLLETNSVDNKELMVQQLQ
RGREWEGLISWRRKMGDSVVLSGRVIPVCSPGRSPTHYIFIHESQHMMLDKRMSGTLVKN
PELPKGSNNRKGSADMKSISSDGLRRQSIAKLHNLSIEAPITKVIALITSVQDNANIEDI
QTLDKVVDILRTTELYSPQLKDDKGKAGDPVTNDLIGALLSSGPSVTPIARRSSSDSGSV
SKIGLSRSTFKTANMSHQMKELLDTSLLWDFDIFRLEELSVKRPLVYLGMNLMDHFDVCS
SLGCEENVLHNWLVVIEENYNAKNTYHTSTHAADVMQATAGFLERERLKQILDPLDEAVC
LIAAAAHDVDHPGKSSAFLCNSNHELSILYNDLCVLESHHSALAFKLTISDDRVNIFKSL
ERDVYKAVRQNVIDMILATEMTKHFEHLAKFVNVFSIKKEDDSPDVRMLFF
>A0A1A8MTQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothobranchius pienaari|TrEMBL
MSSNELSVEMDSCIRTFKEHMHLELEPPKMPGVMGGKRGATSPKLSPRSSPRLFRKLMVN
KSIRQRRRFTVAHTCFDVENGPSASCSPLDPQASPGSGLVLHTNFPGHNQRRESFLYRSD
SDYELSPKSMSRNSSIASELHGDDLIVTPFAQVLASLRSVRNNFTILTNVQCPSSKRSPA
ATTLPPITKVCLPDEAYQKLAMETMEELD
>A0A836JN81|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acromyrmex heyeri|TrEMBL
MASPPNEYFFPSEDEDSLEDELFTGYLFDKTDAFEIVAEKNEKTPFEDNTNDDYDENGDY
LTVKGPQDFSNYLLTTNVPSIVKILLVFSKDDQQMDILTNTARRLGWSVSIAKDAEKALE
LFQNRAHELVIIDHRAHHAADGDAICRTIRSSPVYHSSVIIALVKKSYFMLDEKGRIVAL
DLLKTGFDRALMECSHEGILINELVGIYTSSLLPKTQLAAAHALYLALDRCRDMVHVTND
KNIVQFLNKISEKLLGYNVEEMMGRNLSEIVSYENFSLMEQQLNKGREFEGNMNCKRKNN
QMIMINCRIIPFCITLKYYEKDYIFVTGRRRSSLQKLHTLQLEAPITKVITLLSNAVTDT
TNPETAAQIDKAIDILKTTELYIPHLKEDRAMCCDPVATDLVGALLSSPRTTWESRRSSS
DSARLSAIKAITSPTNSRVQVKNFRGPQEIMEILDKSLDWDFEIFKLEVLTEGRPLVFLG
LTIMNLYRVPATIHCDERTLQNWLAIIEHNYNAENSYHNSTHAADVLQATARFMQSKRLK
EILEPLDEVAALVAAAAHDIDHPGRSSQFLCNANSRLAILYNDLSVLESHHAALTFKLSL
SDDSVNIFKNMERDAYKLLRQNVIDMILATEMTKHFEHLAKFMNVCSARIGDGQETYSDS
LDMTVVLQPDNVILIKRMMIKCADISNPTRPLKCCVEWAKRIAEEYFNQTDEEKKLKMPV
VMPMFDRLTCSIPKSQIGFVDYIINDMIEAWDVFIDMPEIVGYMRYNYEKWKEYNEQGIS
TIQDIEKLQQHPEMQILRLP
>A0A850QSQ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium damselae subsp. damselae|TrEMBL
MLTYSLPPRQSDSVVLLQITDTHLFANDAGSLLGVATKDSFHAVLAAIDHQARPFDAIIA
TGDISQDHSTESYQHFAQGIARWQQPCFWLPGNHDYQPSMKAVLPSPQIKPCEQVLLGEH
WQMILLDSQVPGVPHGELRAEQLDMLDRALAAHSERHALVLLHHHPLAAGSAWLDQHQLH
NADDFWQVLARYPTKVKSVLCGHIHQELDCMRQGVRVLATPSTCIQFLPDSDDFALDSKA
PGWRYLELTPQGDVHTQIHRLANDQFAPDLNSAGY
>A0A6M8MT35|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas graminis|TrEMBL
MLIAHLSDLHIRPQGMLYQGLVDSNTMCEQAIAHLNKLLPRPDVVIITGDLVDEGLPQEY
AMARELLAGIEQPLLMIPGNHDDRTLMGSTFSQPYLSSTAGPWHFVADDLGPVRIIGVDV
TVPLEHHGDMTEAAGAWLDAALAQEPTRPTLVMLHQPPFLSGIPYIDTYACRNSERLREV
VQRYPAIERVVCGHIHRSMQLRFGGTVLCTAPSTTTAIGLALDAEAEEASYVEPPALLLH
HWKVDTGLITHWVPIGTFRGPLPFA
>A0A090KDQ7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moritella viscosa|TrEMBL
MGADISKLTAKHNVINLLQVTDTHLFATAEKDLLGVKTQQSFSHVIDAILQNQQPFDAVL
ATGDISQDNSIASYKYFAQHIKRLDKPCYWLPGNHDNIPLMADALKSEGVLSDKYKVVGD
WQIILLDSQLTGSPSGYLSPEQLTLLDEQLSLHPDKYALVVLHHNTYPVGCKWLDQHILR
NPEAFLAVLAKHPKARHVLFGHVHQQLDETYDGIHFMASPSTCFQFKPHCDEFTLDARAP
GWRYLQLHSDGTVNSQVWRLSNHDFNPDLESKGY
>A0A6I9V2N6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bactrocera dorsalis|TrEMBL
MKMRKCFVKISNAFRHKPAYATPEGEHYNDAPAVEGYVRHSNAYEDDESARRGKVWEAST
ANNDKTSARTAAVTAKRTNNLASDKLKECNDKSADSVDKATDSANTTTKSTNAIAKATRI
DGNVNEVYAGRAVAAGERAKVMEKKKKKDKSKYFMRSATSPSLGAQSQPEKNTCVGNAAL
LSTSDMGDIAVYRSSHECGGMGDNRNSGRSSARSSGRNSGIFRLFLGSSKKKKREQDGGS
ETEMERNKENKQEKHGDMKGRERYSAREEKAPLAVMEQQQLGFDEDELKALSKDSRTSSN
TTAVKARLLDRPDDKSAGNKSNTHTYANAKGDKAAAAADDTHRYRPNGSVDAVTESRVDA
KGAAGVANNKTTKSHDERSYISEYKSFVEDEKPNLIGTPFPETEAFNFEQALNRKTSERH
SRVHSTEARIDLTKYRNETPKTPEEIEYEANIAAESADVMTPLPNNLTFSSGRKSLTTAR
PLASDIAEMIRNLDANTLRINNMTVEEKIELMRRFDQPQQPDKDKQVHHPHHQNHHAHTA
QQQQHNSLRRSSGSRSALNPLRLAMENRIVLQASAVGAAQQIQGESGGIGESTCDSDDEH
VEVVLRRKFVDYPDGEKVTISTCLYERRQPECPKLKLLVRSQQSDNRDEGSGERSLMDVK
FPTVLPPNPQLKALLVFHKSDNICEVVTEACHRQQLDVTVARTKEGALDTLTNTNEEFYH
LIIIDARSTKHLDAEYIARSIRHTNGHHFTTIIAVVKKSFFEKDDVLIALLDAGVNRCVP
ETTNLSMCNIELKQILHSIVRPHNVMSTQQALYTALHRLKEVILITDNHLRIQYANRAAE
RLLNMRLDEIISKPLADIFISDVSTIMIHGRKNKEFDEILTVRRKGQEDVAMHVRVIPVA
CIGRTPTHYVFNLDVPGSHGDFVATLPQAREAPRGSQHSIRRGSVDVRSVASDGLRRTSL
AKLTSLPLEAPITKIINLLSQVQENCSPDEARLIDKVMEFLKREGLYSPQMKEIRTDDPI
ATDLIGALLTGPSLYSSRRSSNDSIIRVGGRQSTCMPAKMKATPHIMELLEESLSWEFDI
FKLEEITEKRPLLYLGMEMFRRFNVFATLNIDENVCKSWLAVIEANYHANNSYHNSTHAA
DVMQATGCFLTQLAAKDMGMDHTDEAIALIAAAAHDVDHPGRSSAFLCNSRNTLALLYND
LCVLESHHASITFRLTLSDDKVNIFKNLDTESYKSVRSVVIDMILATEMTRHFEHLAKFV
SIFGSDEEPKDIVQSEEESSILIRRMMIKVADVSNPSRQPSYCIEWARRIAEEYFTQTDE
EKAKTLPIVMPMFDRNTCSIPKSQIGFIEYIIQDMMHAWDSFIDMPQLVTYMQINYSQWK
KFEEQGVHTLADVKSKQHSLSVKKSAK
>A0A6G9RG84|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kluyvera genomosp. 3|TrEMBL
MESLLNLPLAGGASVRVLQITDTHLFAEKDETLLGVNTWESYHAVLQAIHASAREVDLVV
ATGDLAQDHSSAAYQHFAEGIASFTAPCVWLPGNHDFQPSMYSTLQDAGISPAKRVLVGE
HWQILLLDSQVFGVPHGELSDFQLEWLEKRLAEMPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGALDNVLVHYPRVKHLLCGHIHQELDVEWNGRRIMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHADGSLTTEVCRLAGSKFHPDTASEGY
>A0A221V0U2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arenibacter algicola|TrEMBL
MRNKINIRSIFYTITLLLYSAQWISAQNLEISHGPYLQYVTSNEVTIGWSTSKNTISWVE
YYVEDGSNFYQKEREKIFDASDGLKNISLLHSVTLKNLKPGTKYAYRIYSQEVKEDRSFG
KTVATRVYKREPLYFTTQPLKKDQISVVVLSDMHENTAKVGSLLKGVEWDKTDFVLLDGD
FVDSFESESDLYGGVLDTCVNIFAQKKPLVIVRGNHETRGIKAHELKKYFHFPEDKYYYT
YKIGNTFFIILDSGEDKADSDIEYNGFADFGAYRSEQAKWLSEVVKSDEFKNAEHKIAFM
HIPPYDDNRGQEWHGDLEVRLKFVPILNKAGIDLMVSGHTHHFSFQTPKSEENNFPILVA
DHKTRYNLLIDKTGIKIKGIDIDSKEVLNMFIEKYK
>A0A221UWQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Arenibacter algicola|TrEMBL
MKKFVILALLAINSCGLLFAQTNIKGSVYFDENQNLVRDNNENGIEGALVSNGRDVIATD
RGGKWSIPNNGNSAIFLIQPSGYLVPTNKSQVPQHYSDPSNHEKPIEFPLWKGEENQEFE
ALFFGDTQARGMTEVNYVTHDVVEECIGHNAKFGVVLGDIVADDPGLFDELSASIAQIGV
PWYYVFGNHDFDRNAKGNIGAEDTFFKNFGPSTYAYEFGQVAFININDVFYKETGGYKGF
FTENQLSFVSNYLNHVPQEKLVVLMMHIPIVGCENREDMFRILEKRKHTLSIAAHTHTLR
NIFVDETMGWKGSEPHHHFINGTVSGSWWCGLKDELGIPHATMNDGTPNGYATIKFHGNQ
YNIVYKAARRPADYQMNIYLPDDISLDELNTSHVLVNVFNGTEKSIVEMQIDQTGDWMQL
SQTTAKDPANWKMHEMNNYLDIQVEDKKLEEIFGWKMDEPKNSRHFWTGTLSKKLEPGTH
QLTIKTNDMFGNVYQSYKIFRVVP
>A0A8C3FE17|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chrysemys picta bellii|TrEMBL
MKLAHTSPFPQLQWSFDVDNGTSSGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDS
DYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLPDRAPNKRSPM
CNQPSINKATITDWNVGENPGMEKRRVQSGTITGFVRNLLQLCSSSQMHVPNLTTSLLCC
SRSRGFSQQLPKWPISLNLTTI
>A0A1J4R461|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio barjaei|TrEMBL
MKTTPSDESQLSSVRLLQLTDTHLFAPQDGCLLSVNTQESFNAVVAEIVAQGTQFDALLA
TGDISQDHTEASYEKFVAGIEPLALPCYWLPGNHDYKPCMNSVVSSPLIQDVTHVLLGEK
WQVVLLDSQVVGVPHGRLSDSQLEFLDRMLSTHCDRHTLVLLHHHPLLVNSAWLDQHSLK
DADEFWNVVEKHDNVRAVLCGHIHQELDELHGGVRVLATPSTCVQFKPNSNEFALDIRSP
GWRELELREDGSLLTEVKRLANGSFRPDFNAEGY
>A0A1E5IWV2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella colwelliana|TrEMBL
MLKEAISYSIDECASVRIVQVTDPHLFADPEAQLLGVNTAHSLDAVLNTIKAVDYPAHLM
LATGDISQDYSNESYHNFVKAIAPLNVPCHYLPGNHDDPRIMHLHMQGPSVFGDRRILAG
NWQIIMLDSTVRGKPGGHMAEDELELIEAAIADQPDKHTLLVMHHNPVLVGCKWLDQHCM
DNGSEFIDAVSTYPQVKGLLWGHVHQSLDQVHQGEQGPMRLMATPSTCIQFKPKSPYFAL
DAQQPGYRLLELKADGSILTNVYRVPGNKFSPDHESSGY
>A0A6P5VJU2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila obscura|TrEMBL
MSQCSTGTGTSGTSSSGGGGNNRPGHRKSSLALALTPEDEPMDVYQRNLMDLKYPTVLPP
NPQLKALLVFHKSDSICEAVASACQRHQLDVTLVKSKEEALDTLHKSYATAQCYHLIIID
ARSSKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAGVNRCIAETTNL
AMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDVLRIQYANRATERLLNM
RLDEIISKPLADIFVSDLSTISEQGKSIKEFDGILTVRRKNQEGIPMHVRVVPVACIGSA
PTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDGLRRTSLAKLTS
LPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRTDDPIATDLI
GALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKANPIIMELLEESLSWDFDIFKL
EEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYHKSNTYHNSTHAADVM
QATGAFITQLTNKDMMVMDSMEEAMALIAAAAHDIDHPGRSSAFLCNSNSALAVLYNDLT
VLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSV
FGGEEPREHNPQSDEETAILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEK
QRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITYMQINYSQWKKY
DEQGVNTLADIMAKQPPMGKLANSK
>A6TE21|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)|TrEMBL
MLGINTWDSYQAVLSAIHASQRPCDLIVATGDLAQDHSSAAYQHFAEGIASFAAPCVWLP
GNHDFQPAMYSTLQEAGISPAKRVFLGDRWQILLLDSQVFGVPHGELSDFQLEWLEHKLA
EAPERYTLLLLHHHPLPAGCSWLDQHSLRNAGALDSALSAWPRVKHLLCGHIHQELDLDW
NGRRMMATPSTCVQFKPHCANFTLDTVSPGWRWLELHPDGTLTTEVCRLEGAAFHPDIAS
EGY
>A0A7X5BDU9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. V27_P1S3P104|TrEMBL
MNVSPSLSPSDHIKLVQITDTHLFAPDDGCLLSVNTADSFRAIVQAIIEQQIPFDAILAT
GDISQDHSAESYQRFAAGIRDLQKLCFWLPGNHDYKPNMGSVMPSAQIQALEHVLLGKHW
QMVLLDSQVVGVPHGRLSDYQLGLLDEKLTQYPDRFTLVLLHHHPLLVGSAWLDQHTLKD
SDAFWHVVGQHRNVRAVLCGHVHQAMDCEYQGVKVMATPSTCVQFKPNSDDFALDLCSPG
WRELELHHDGEVSTQVKRLRKGAFVPDFTSSGY
>A0A7J7ABP9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Abscondita terminalis|TrEMBL
MLPLGKKNDSRNEKSNDTCHSITSIPEDDDIYNITLEQETPIKRNTPFIQLLRKSGNKKK
IKKIKHQKITNKNIRINTYEQESLLNELILKENLSASSGKCLFFLRGQDELSSKKKLSGQ
KRTIKKFASGDGDIDSFPINWSPTVPAGIIGQVTCIKTWNSVLNCNENLLQYKKGTENDS
KIGIHHPQKLNNQQFAMYSANHFRSTTNEKVYSAPQMYSKFEGNLDTWPKIVETENVQEA
DILEERKKTGDTTENKRALNYQPHNELYNLKSRKVLFKSNSQGIGDNTVKFTRKVSKCFK
RTPSEIKFGLLLPPNRSPPKLLLAFLQGDAVSETLSRAADKLGFDVTLCNSCEGALEEFL
SNLHDLIIIDTRCSLKAFDYDTLCRSVRNTKGSQHTAAVAVVKKSAFDKDDVTILSLLDT
GFNRCIVETTNIIHCVNELVQLKHSDIRPLAQTATNQTLYAALEKCSDIVFVTDDSFRLQ
YANSASERFLGYKCDETLGKTLQEQLIQDPIQLNSMTSSLMRAREWQGPITFKRKGQDAI
TFTCRAMPIIAAGRSPTHFAIVIDIHGLHESTVNFDKPRGSVQSLRRTSLDVRSVGSDYL
RRTSLAKLSALPLEAPITKVITLLTQAQEQTSPTVASILDKVIDLLQSTELYSPHLKDSL
RLRCDEPVTSDLITALLMQQPQLHTSASSRRSSNDSTTVRSVHRAVSKIRIPTQIKELLE
SSLTWEFDIFRLEDLTNKKPLIHLGMNLFLHFDVPQTLNCDEKTLYNWLTVIEMNYHVEN
SYHNSTHAADVMQATAGFLEKDTLKSIMEPLDEATSLLAACAHDIDHPGKSSAFLSNCDN
PLAILYNDSTILENHHAALTFKLTLGDDRVNIFKNLDRESYKIARHNVIDMILATEMTRH
FEHLAKFVNVFSPKSGRLDPEVDGGAINQPENITLVKRMMIKCADVSNPTRPLRLCVEWA
RRIAEEYFAQTDEEKAKGLPVVMPMFDRVTCSIPKSQIGFVDFIVHDMFDAWEAFIQMPE
LVNYMKQNYLRWKEFDEQGHTTAADIRKLQNTLLMAPMFPNKSSTKRND
>A0A4U6JLC5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. TBCS-14|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQCVLDAIHAESTDFDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPSGCSWLDQHSL
RNAAELDNVLVNYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCANFTLDTIS
PGWRTLELFADGSLHTQVCRLPGIRFHPDTASEGY
>A0A287DAC9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Ictidomys tridecemlineatus|TrEMBL
MTAKNSSKELTASESEVCIKTFKEQMHLELELPRLPGNRPTSPKISPRSSPRNSPCFFRK
LLVNKSIRQRRRFTVAHTCFDVENGPSPGRSPLDPQASSSSGLVLHATFPGHSQRRESFL
YRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTSNK
RSPAASQPPVSRVNLQEWDSWGVMTRRTGSRRARTG
>A0A7Y6MRZ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio mediterranei|TrEMBL
MKTTPSDESQLSSVRLLQLTDTHLFAPQDGCLLSVNTQESFNAVVAEIVAQGTQFDALLA
TGDISQDHTEASYEKFVAGIEPLALPCYWLPGNHDYKPCMNSVVSSPLIQDVTHVLLGEK
WQVVLLDSQVVGVPHGRLSDSQLEFLDRMLSTHCDKHTLVLLHHHPLLVNSAWLDQHSLK
DADEFWSVVEKYDNVRAVLCGHIHQELDEMHGGVRVLATPSTCVQFKPNSNEFALDVRSP
GWRELELREDGRLHTEVKRLANGSFRPDFNAEGY
>A0A3Q1AR57|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Amphiprion ocellaris|TrEMBL
MNCLFVDFVVISTQFKRMLNRELTQLSETSRSGNQVSEFIASIFLDVEPPGVTQTEKEKK
KRPMSQISGVKKATQSPSLAPACIPRFGVNTPHESMLAKEIEDINRWGLDIFKIAEFSGN
RPLTAIMYAVFQAVFTDLEIMAVLFASAIHDVDHPGVTNQFLINTSSELAVMYNDTSVLE
NHHLAVGFKLLQGDNCDIFQNLSKKQRDSLRKMVIDMVLATDMSKHMNFLADMKTMVETK
KVTSLGVLLLDNYSDRIQVLQNMIHCADLSNPTKPLELYRRWTDRIMVEFFTQGDRERDK
GMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSMI
PRSPSPSSPEEHHAEVGPGGGAVGAGGALPSTGGGGGAVGDKFH
>A0A453Z259|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Anopheles merus|TrEMBL
MAHHSSMMDYTRGTSSSSGRYGHRKSSLALTPEEEPLDSCPRLVSDLKFPNLLPPNPVIK
ILIAFCKNDPVFEALVNASHRLSLEPTFVKSAESAIDAFQNPSSGGHHIIIVDARYPRTI
EAEALGRSIRNSKGSQHTTMVAVVKKSVFEKDDTAVISLLDVGYNRCIIESPHVSICSSE
LRQIQHSLVRPQNVISTQQALYTALHRSREAVIITDDTLRAQYANRASERVLNMKLDEIV
GRSLSDLVTADISNILSHTSRYKDYDGYLTTRRKSQESSQIHVRAVPVSCIGRNPTHLVL
ILESSSSALVSTNAIGEALQTLPQGKEVPRGSLHSIRRGSFDVRSIASDGLRRTSLAKLS
SLPLEAPITKVLSLLAQVQENCSLDEAKLLDRVMEFLKREGLYSPQMKEIRTEDPVATDL
IGALLTQGPTNILSSRRSSNDSIIRGGGRPSTGSIVFNKTKESSQLSDLLQTALDWDFEI
FKLEDLTEKRPLVCLGLELFRRFDVYNTFNCDEMTFKLWLIEMEKHYHSENTYHNSTHAA
DVMQATAVYLQQLSNRELKIMDRMDEATALIAAATHDIDHPGRSSAFLCNSDNTLALLYN
DICVLESHHAATTFRLTLGDDKINIFKHLDRDMYKLARSIIVDMILATEMTRHFEHLAKF
VSVFGTDVESKDPLPPDNDDNQILVRRMLIKCADVSNPTRPLKFCVEWARRIAEEYFMQT
DEEKRKNLPIVMPMFDRTTCSISKSQIGFIEYIIHDMMDAWNSFIEMPEIIRYMEFNYSQ
WKLFEEQGINTLSDIKRKQMSLTEDTASSISLEEKF
>A0A0L0AW11|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella sp. RIT-PI-d|TrEMBL
MESLLTLPLAGGAKVKILQITDTHLFAEKHETLLGVNTWDSYQAVLDAIHAEQRECDLIV
ATGDLAQDQSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSALQESGISPAKRVWIGD
RWQILLLDSQVFGVPHGELSEFQLEWLERKLAESTDRHTLLLLHHHPLPAGCGWLDQHSL
RNAQELDNVLARFPGVKSMLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCSNFTLDTAA
PGWRWLELHDDGSLVTDVCRLQSTQFSPDTASEGY
>A0A2D4F6D3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Micrurus corallinus|TrEMBL
ACRPPRGAAPPCAFPPGQGLPPPRCLGLPPGHQRAAEVDMHFSFSEEDIKRHRLLAKSVS
FEVENGPSPGRSPLDSQASPGLVLHPSFPQSQRRESFLYRSDSDYDMSPKTMSRNSSIAS
EAHTEDLIVTPFAQVLASLRSVRNNFSILANVPTPTSNKRSPLGGQPAVCKATLSEETYQ
QLARETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYIS
NTFLDKQNDVEIPSPTQKDREKKKRQQPMCQISGVKKLMHSSSLTNSSIPRFGVKTDQEE
LLSKVSI
>A0A6L7I169|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella insulae|TrEMBL
MLKEAISYSIDPDESVKLVQVTDPHLFADPEAQLLGVNTAHSLDAVLNTIKAVEYPAHLL
LATGDISQDYSNQSYHNFVAAIEKLKLPCHYLPGNHDDPRIMHLHMQGPRVYGDRRILAG
KWQIIMLDSTVRGKPGGHMADGEMELIEAAVAAHPELHTLLVMHHNPILVDCKWLDQHCM
DNGEAFLDRVTAMPQIKGLLWGHVHQSLDQMYQGKTGLVKLMATPSTCIQFKPKSPYFAL
DAQQPGYRLLELKPDGSILANVYRVPGNKFSPDHESSGY
>A0A401NIN5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Scyliorhinus torazame|TrEMBL
HGDDLIVTPFAQVLASLRSVRTNFSVLTNIHGASSKRSPATSQPSITRISLTVSQAQSAR
LTFGTRLQSGSGEEPGKIEEAGGELVVGEKDWCPDLGNIRTA
>A0A087VF35|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Balearica regulorum gibbericeps|TrEMBL
FDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSS
LPSEQHGDDLIVTPFAQVLASLRSVRNNFTLL
>A0A6H3APZ8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. A316|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRARYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A3P4A4Z0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mycolicibacterium hassiacum (strain DSM 44199 / CIP 105218 / JCM 12690 / 3849)|TrEMBL
MFLVVLGAVLALISLYLWQRLIRDTTRPGRVRRVLTAAHLVLTTLLFAALIGPRFVGVNE
SRWYAWPGYLWLGAMWYLLLLLLAFEPVRLVLRAVLARRARANADPGPDEPAERPNPDRT
LDRRLFLARAGAVAAGAVSVGLVGIGAATALGPPAVVRLPVRLRRLDPALGGYRVAVVSD
IHLGPLMGRAHTERIVAMINRAEPDLVAIVGDLVDGTVDELGRAAEPLRDLVSRDGVFFV
TGNHEYFVDDPDGWVRELDRLGVHTLRNENTLIRRGGAAFHLAGVNDLVGNRRADGPDLD
RALSGVDAARPTVLLAHQPVLVGEAARRGVDLQLSGHTHGGQLWPFHYLVRLEQPALAGL
SAVGDTQLYVTRGAGFWGPPVRIGAPPDITVLTLQPGT
>A0A0F4NGZ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio galatheae|TrEMBL
MKVTSSSSDSDSIKLLQITDTHLFEPADGSLLSVNTLDSFNAVVEAILEDNRCFDAIIST
GDISQDHTAVSYQRFEQGIAPLEKTCFWLPGNHDFKPSMTSVLPSEQIKQLQHVLLGESW
QMVMLDSQIVGVPHGRLSDYQLSLLEEKLLEYPERHTLVLLHHHPLLVGSRWLDQHTLKD
AHHFWQVVEKHQNVKAVVCGHVHQDMNVLHNGVRVMSTPSTCVQFKPNSDDFALDTLSPG
WRELELHSDGRLTTQVKRLAKGCFQPDFSSAGY
>A0A6H2GNA6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia sp. SCLE84|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A7K0DJ80|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nocardia aurantia|TrEMBL
MAGTGCARIAAVGDVHLGAESAGSLRPVLSCLPERADMLLLAGDLTRHGTLDEARVVATE
FADLGVPVIAVLGNHDYHGDAEDEITALLTDHGIVVLEGTATTVRLPDGIVTVAGTKGFG
GGFAGKCASAFGERIMREFARYTEELAASLQAALSGPRADVTVALTHYSPVNDTLHGEPP
EIHPFLGSYLLGEAVDAGRADLAIHGHAHAGCEQGTTPGGVRVRNVAQPVIRTAFAVYEL
PIRVPEPAVAD
>A0A447NIP7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Sanjuan|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A1Z2SGQ1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio gazogenes|TrEMBL
MDVSFYTEHLDSIKLLQMTDTHLFASDEGSLLSVNTANSFKAVIQEVIARNVDYQLILAT
GDISQDHSEASYQLFVDSIEPLQKPCLCLPGNHDEQTAMKTVLANSQIIQPRHVTLGPHW
QMILLDSQVSGVPYGYISPEQLQQMDDMLRETQARHTLILLHHHPLLVGSRWLDQHTLKN
SDSFWEVVLKYPHVKGVVCGHVHQVMERDYHGIQVMSTPSTCVQFKPHSNEFALDLVSPG
WRELELHPDGQLTTQVGRVKQGLFLPDFSANGY
>A0A2H5V1S1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|archaeon HR02|TrEMBL
MLNFPGDEAAIVLESGGKKYLIVSDLHLGYEVELAREDIHFPNQLPNILERLLKLLEDHR
ADALVLLGDVKHRVAGVSWRESRQVVDLLHSVKARVREIIITPGNHDAGIMNLAGDMAKV
VSGRGIRIGEAWMLHGHCWPPPQAADAKIIIIGHTHPVISLAREPGSRRKVFLMMKASGS
RVVKVLSSKMGGALTARRRRQVTLLVMPHFNNALQGVELSQLLRGGRGVSPLLRSGLFSL
SDASVLMLDGSRLGSVDWCVRSRELW
>A0A844CFK3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacteriaceae bacterium RIT693|TrEMBL
MESLLTLPVADGGRIRILQITDTHLFAGKNETLLGINTWKSYQAVLAAILAEQRTCDLLV
ATGDLAQDHSVEAYQHFAEGISGFSAPCVWLPGNHDFQPAMFGALQEAGISPAKRVYIGE
HWQVLLLDSQVFGVPHGELSDYQLEWLERQLAAAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAAALDAVLRPWPKVKTLLCGHIHQELDLDWNGRRMLATPSTCVQFKPHCANFTLDTIE
PGWRWLDLYPDGSLTTEVCRLQSGKFSPDTASEGY
>A0A8I2XVS4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus influenzae|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNQFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKETLGKNPERYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLSPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSIRTEVKRIQQAEFLPNMQEEGY
>A0A6Y0GQA5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enteritidis|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
VTGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A755SSJ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLDTIAPGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A8E1ZVW4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. SwsAc2|TrEMBL
MTLNNEKSWNIIQISDTHLMDQDHLEFVRMNPEQSFHHVMLHIVERHPQLNAIVHTGDLA
QVPVSRTYQRYLDFMQSLKRPFYQVPGNHDNAEHFPFHQQQNKVHVIHFGPWSLVLLNSA
VKGKIDGWVDEAQLNQLQQILQEFAQQHIVIACHHHPFEMQSKWIDQHKLKNTQDLTAVL
AKYHNVKIVLSGHVHQESWREWHGIQFYSTPSTSVQFKPLSDHFALDEQAPGYRILQLNA
DGSHETHVERVLHAQQKINVEISGY
>A0A556VYC3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bagarius yarrelli|TrEMBL
MYLRSPSQKGRIYFDFSEEVVTRLRTPAFSFDVENGPSAGCSPLDPQASPGSGLILHPNF
SQTGHNQRRESFLYRSDSDYDLSPKSMSRNSSVASELHGDDLIVTPFAQVLASLRSVRNN
FTVLTNVQCTSNKRSPASTQPTRVCLSAGDPTPAINSENDRKTAFYRRLYSVIHARTLRQ
RPLV
>U9ZHI6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli 907713|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A2S5D3F5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lysinibacillus sphaericus|TrEMBL
MMNKNFKRVVKIVLLVVVLIGLLVGYAFKIEPKMLVVHSYHLNEDKGASVKIVQISDIQV
SETYTVNQLNRLVEKINQISPDMIVFTGDLFENFSTFPQKQEVTDSLSQLKATMGKFAVW
GNRDYGGGAFKIYEDLLINADFTLLNNSGVTVPVSNDKKLFIGGMDDGLLGKPDIDLLLS
QMDDTYDYEIVLMHEPDMAELLQDTSVNLLLAGHSHGGQIRIPFMKTIKTSLAEKYDDGF
YTINKDNGMQLYVNTGIGTSRIAARFMVPPEIAVFTIHL
>A0A6M9DFM8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. 14181154|TrEMBL
MPPPDQPRPVHVVQLTDAHLFAAPGGSMLGLNTRDSLRHVVAQVQREQAQVDVLLCTGDL
SQDASVASYQAFRELTAPLAVPTRWLPGNHDEAQVMAQVAPELVQAVTDVGAWRIVMLNT
AVQGATHGFLQGDQLAVLGAALKEANGRHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDT
IAGYPQVRALLWGHVHQEWDELRDGRRLLATPSTCIQFAARSEDFKVSEEQPGYRWLRLH
ADGRLETGVERAWDFEVKLDFDSPGY
>A0A7R9N6G9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Methanoperedenaceae archaeon GB50|TrEMBL
MKILHLADVHIDEKKTVNGKIIYDEEGINIRLKDLLDCISQVKNTAEKENISLTLIAGDL
FERKTPTPFETYTATKVLSELSSICPVVLTPGNHDAVDSVKALGFIKNIYVPEPFTPIRF
SDITIFCVPYPDLKEGSRSEVKQLYERKILETSKKLKENSNFLVALCHAPVEGASYPTTD
RDVNEVTLSPSCFKHLDYAALGHIHKPQRIENIYYPGSVDTWRRQEADEEKGFYIIDTDT
HEVTFYPITTRPVHNLNFTIDTIPLVINVLEQSIVRIEIEVPEERAGDYDPVRVQNVIAG
NPLDVKIIPRIIRTQRMRCQEIVQAKNFDEIITTYMKNKKLPEEKINRIREKIMELVREK
ELEAKLC
>A0A8E3AZJ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella xiamenensis|TrEMBL
MLKEAISYSVADENVRIVQVTDPHLFADPEAQLLGVNTSKSLAAVLNTIRAVNYPAHLML
ATGDLSQDYSPESYRQFVSAVAPLNLPCHYLPGNHDDPRIMFLHMQGERIFGQQRILVGK
WQILMLDSTVRGKPGGHMAASQFELIEQAIAAHPDRHTLLVMHHNPILVNCAWLDQHCMD
NGTEFLKRVAQYPQVKALLWGHVHQQLDSLYDGPHGALQLMATPSTCIQFKPQSPYFALD
GLQPGYRLLELKADGGISTNVYRVPGNLFSPDKDSSGY
>A0A2P5ISI3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea sp. PSNIH6|TrEMBL
MDSLLTLPAANGAGIRILQITDTHLFAGKNESLLGVNTWASYDAVLDAIAAQQREYDLII
ATGDLAQDHSVEAYQHFAEGIARLPKPCVWLPGNHDFQPAMVDTLAEAKLAAHKHVLLGD
QWQLVMLDSQVFGVPHGMLSDYQLEWLEKTLARYPQRHTLVVLHHHPLASGCTWLDQHSL
RNSHQLDAVLQHYPLARTLVCGHIHQELDLDWRGRRVLATPSTCVQFKPHCTSFTIDTVA
PGWRWFTLYPDGSFATEVERLQTDAFRPDLDSDGY
>A0A2A2N9Z2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. V1B|TrEMBL
MQSSSDSIKLIQITDTHLFAADEGSLLSVRTADSFEAVVKEVLHRQVQFEYILATGDISQ
DHSAESYQRFAEGIAPLEKACFWLPGNHDFKPNMGTVLPSPQIQSVEHLLLGEHWQLILL
DSQVVGVPHGRLSDQQLSLLEEKLSDYPDRHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFENVKGILCGHVHQDMNVLYNGIRVMATPSTCVQFKPNSDDFALDTECPGWRELE
LHPSGDISTEVNRLTDGQFQPDFTSNGY
>A0A6S7B4R1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Paraburkholderia ultramafica|TrEMBL
MSSHDSFDPARRGALKCLAFGGLGTVFVLSGGVLTPVELALAADAKTSAATTGVPLFLQI
SDSHIGFNKEANPDVAGTLKQTIDFVNAMPVKPALTIHTGDITHLSKPAEFDLAAQLMSG
LKITELHTVPGEHDVTDGPGTEYFSRFGKASDNKGYYSFDHQGVHFVGLVNVMHFKPNGL
GGLGGEQLEWLENDLKGRSSSTPIVVFTHMPMWTIYEPWGWGTGDAGQAMNYLKRFGSVT
VINGHIHQIVTKVEGNITFHTARSTAYPQPTAGNGPGPLPLKVPGDQLPRMLGVTSIRVA
RHPLKATLTDTTLA
>L3PZT0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli KTE75|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A5M9QZ86|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Morganella psychrotolerans|TrEMBL
MEIPLHLAVADGAAVRILQITDTHLFAGETETLLGINTLHSYHAVLDAIVKQQLPTDLVV
ATGDLVQDQSIRAYQRFTQGVACLPAPCVWLPGNHDYQPSMARELADAGINPAKHILLGE
QWQVLLLDSQVQGVPHGELSEYQLAWLDECLAQYSDRHTVVMLHHHPLASGCNWLDQHSL
RNSHELADVLVKYQNIDAILCGHIHQDLDMIWNGMRVLATPSTCVQFKPHCTTFTLDTVA
PGWRYLELTTGEFPALKTTVHRLDTDEFSPDLGSEGY
>A0A2H5WTI1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bacterium HR15|TrEMBL
MRRYWLAVVLLRLLVAGWAQEAYISGVVYHDRNRNGIRDPGEPGIRGVLVSNQREVVRTD
SKGRYRLPIEEDTIVFVIKPRGWMTVLDNNNVPRFYYIHKPNGSPPVAYLGVMPTGMLPE
SLDFPLYPQRESNQFTFLIFGDTQPRDLREVSYIAHDVLRELVGTREAVLGIVLGDVVFD
DLSLMQPLARAIGRIGIPFYYVLGNHDMNYDSPNDHYSDETWERVFGPNYYAFQYGHVHF
LALDDVMWEGATEGRRGRYRAGLGERQLAFIRNYLQHVSRRDWIVLGMHIPMWEWPEEER
RAVFEILAPFPHTLSLSAHTHYQTQRFFGEADGWHGKEPHLHWNAVTVCGSWWTGAPDPL
GIPHTTMRDGTPNGYLWVTFDRQRLRIRYQASRRPPDYQMNIYLPDAIPQEQLATTRVLV
NVFAGSERSLVEMRINDENDWIQLERVTDQPDPAYAELKRLEQEYKLPGRPLPGAMPCPH
LWSGQLPSWLPRGTHVLYVRTTDMFGQTFVDKRLFRVE
>A0A0S7FKC4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Poeciliopsis prolifica|TrEMBL
MTRPTSLPFGAPPRIDITPVDPECFDVENGPSASCSPLDPQASPGSGLVLHTNFPGHNQR
RESFLYRSDSDYELSPKSMSRNSSIASELHGDDLIVTPFAQVLASLRSVRNNFTVLTNVQ
CASSKRSPAATTQPPITRVCLPDEAYQKLAMETMEELDWCLDQLETIQTYRSVSDMASNK
FKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQNEVEIPSPTSKTREKKKQQKQQLMTQ
ISGVKKVSHGSSLSNSSISRFGVKTDKEEQLSKELEDLNKWGLNIFTVSEYSSNRPLTCI
MYAIFQERDLLKTFKIPADTFVAYMRL
>A0A653QWI0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Massilia sp. 9I|TrEMBL
MLIAQVTDLHLHADAGHPNLARFVRVLEHLASMLPRPDLLVLSGDLTDDGALESYRHLQQ
ALAAWPQPVRFALGNHDSRKHFRSVFGDNHFADGFVQGVTDLGAFRLVILDSLEEGRHGG
AFCEARAQWLHAALRDGGDTPALVFMHHPPVDVGIPWIDPGPGQAWIGRLDAALQGVSIA
GICTGHVHVGGVFPWRGRQVATCPSSSSDLSLAFAPMQAAQPDNRPLVEQGDPAFALHRW
QEGGLATIFGRVPQRVLAHWDEATRQVVGEMLQETRP
>A0A345VJN0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Streptococcus pluranimalium|TrEMBL
MTKKLRTILVSLFLLLVFVFLATWREDSRTKTAIKKVWIITDLHQLSPDLQDGKSAFKTI
QATAAGKDLRYGKDRMEALLLQAKREKPDLLIVSGDLTFNGEYQSLKDLSETFQAFEKNG
IQVLVEPGNHDIADGWAREFRRNKQYKTKQISKDDFETLMADFGYQEADARDKSSLTYLA
KVSPKQWFLMIDSNIYSDDVGKGAPATNGRLQKKTLSFIEKQLSAAKEQGALVIPVMHHN
VLNQHQQPQQGYTLDNAPDLRKLYAKYDQKIALSGHIHTQNIKQDTLIGGTSLTEIVTGA
FSIPAASIGELRFEKDSLYYQQLALDMKLWLKKKSATNQDLINHRQYMDSIFNDASNLLV
HMRLHDEGWYDGDVAEEVSTIIESVNIAYFTGQPIDNHWMEEHVYRKKIYQEVKTKHPDS
FVVTYVEQVLAESRDGSDQKIRITLKTPKETDDDNDND
>A0A6N7C952|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rhodococcus sp. T7|TrEMBL
MSGTEAADIRTAEYPRPSHFVLHLSDTHLVDDDLLYGAVDSEATLRQIFTEIEASHARPD
ALVFTGDLTDRGQPGAYEKLRGIVEPVAASLGAQVIWAMGNHDDRGHFRHELLGQEASYE
PIDHVHDVDGLRIITLDTTVPGRHHGEISESQLIWLAQQLAVPAPHGTILALHHPPVPCV
LDLAVLVELRGQPRLADVLRGSDVRSILAGHLHYSTTATFAGIPVSVASATCYTQDLNVP
AGALRGRDGAQGYNLVHVYPETVVHSVVPMGSYDTVGEYVTAEETEQRLAAEGVRIPDAG
EQAVKPVRV
>A0A422PC70|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trypanosoma conorhini|TrEMBL
KAEAMLTMATQLARDNLDEAVLANSIMNTAKALTESDRCSIFLVKDDTLEAHFEDGNIVT
IPISAGIAGFVAQSGETVNISDAYADERFNREVDKATGYRTKTILCMPVTYEGSIVAVAQ
LINKLDMVTESGLRLPRTFGRRDEELFQTFSMFAGASLRNCRINEKLVNEKKKSDAILDV
VTLLSNTDIRDVDGIVRHVLHGAKKLLHADRSALFLVDKERNELYSRIADSVAGKEIRFP
CGQGIAGLVASTGVGENIPDAYQDPRFNREVDKQLGYRTQTILCEPIVLNGEILAVVQLV
NKLDHTGEVTVFTASDRETFRVFSLFAGISINNSHLLEFAVNAGREMMELNENRALAGGR
RASVRNIKRPLAITDRERDAVREIELGHLDITSVEFDLFYVRENMEEPLDAAAAVAYRLI
LGTGLPQKFRCXXXXXXXXXSCGGAAREQAGSHRGGDCVHGERPGDISCFLPFRRHIH
>A0A2J7SFB7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter bugandensis|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAEHRDCDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDSVLAKYPRVKHLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTLTTEVCRLAGAEFRPDTASEGY
>A0A6J1Q5J5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Temnothorax curvispinosus|TrEMBL
MLDEKDHIVALNLLETGFSRALIECSHEGILINELVGIYTSSLLPRTQLAAAHALYLALD
RCRDMVHVTNDKNIVQFLNKVSEKLLGYKTEEMMGRNLSEIVFYENSALMEQQLAKGREF
EGNMNCKRKNNQMITINCRIIPFCITLKKPSHYIYVYDTTYLSENSAPISPASSPLHPPL
KTSILSNARKSSDVRSGVSEGRRRSSLQKLHTLQLEAPITKVITLLSNAVTDTTNPETAA
QIDKAIDILKTTELYVPHLKEDRAMYSDPVATDLVGALLASPRTAWESRRSSSDSARLST
IKAIAYPANSRVQVKNFRGPQELMDILDNSLDWNFEIFKLEVLTEKRPLVFLGLTIMNLY
QVPATLHCDEKTLQNWLAIIEHSYNAENSYHNSTHAADVMQATARFMQSKRLKEILEPLD
EVAALIAAAAHDIDHPGRSSQFLCNANSRLAILYNDLSVLESHHAALTFKLSLSDDSVNI
FKNLDRDAYKLLRQNVIDMILATEMTKHFEHLAKFMNVCSARIGDGQETYSDSLDMSVVL
QPDNVILVKRMMIKCADVSNPTRPLKCCVEWARRIAEEYFNQTDEEKKLKMPVVMPMFDR
MTCSIPKSQIGFVDYIINDMIEAWDVFIDMPEIVGYMRHNYEKWKEYNEQGISTLQDVEK
LQQHPEMQIPRLS
>A0A0A0H939|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGGNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A8I1EU73|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas putida|TrEMBL
MPHSNPAGTVNVVHLTDAHLFASPEGSMLGLNTRDSLRHVVQQALREQPDTHLLVCTGDL
SQDASVASYAAFEQLTAGFAAPARWLPGNHDEAQVMAQVAPEWVQPVTDIGAWRIVMLDT
AVPGAAHGWLQDAQLSVLEAALRTAGERHCLVCLHHQPVDIGCAWIAPIGLRNAEALFAV
LDGHPQVRALLWGHVHQEWDQWRGDLRLLATPSTCIQFAPGSDDFEVSQQHPGYRWIRLQ
ADGTVGTGVERALDFEVRLDFDSPGY
>A0A7Y1JU31|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas lundensis|TrEMBL
MPSVSTLTTEDPVLLVQLSDSHLFADANGSLLGLNTARSLLQVIDLVSAEQPSVDVLLAT
GDLAQDGSVAAYQYFRQATAALAPVARWIPGNHDDVQQMREAAIQSRLMEPRVDVGNWRI
TLLHSNVLNKSHGYLEDDQLQRLAQSLSEAPERHHLVCLHHHPVPVGCQWIEPIGLLNAD
AFWAVVDRFPQAKAVLWGHVHQPFDQQRKAVRLLATPSTCFQFAPHSEDFKVSSEAPGYR
WLQLNPDGTLHTGISRVAHFDFEPDYSQDKY
>A0A518VPH2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium carotovorum subsp. carotovorum|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKARQDAFDLIV
ATGDLAQDHTLQAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALAEAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPDRFTLLLLHHHPYPSGCTWLDQHSL
RNAHNLSAVLDRYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A2S9Y156|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bacillus sp. M21|TrEMBL
MKKTVVSLAVMAALLPTFSAHAEGKEQVRKSATTFNVISDIQGDLGDFDHVLKDMNKVTP
LSRALIMNGDITPTGQQSQYDDVKRVLNKNKHPENVWSTVGNHEFYAGKWTADGKLSQST
WPNGVTEETLFNRYLQFSGQEKVYHKKELDGYPLLFLGTEKYMKYHDSKMWDEVYMSDEQ
LGWLKQNLEEYSQKDKNKPIFIFSHHVLPDTVSGSRQSPYLQDYLNVGKLYDILKDYPQV
VFFTSHTHWDLNLPDWAGKKKIAGGDKKGFTVVNTGGIETGWMSAGPNGGEKTAPDGYSF
KQGLQVKAYGSDVMVTAYDYKRDKEIKKLLISNSKIAQMAPNVTADDSKNIIIGATEYME
YSVKGTNEWLTYNPENPPKFEGNKVVYVRHKGEMNLEPGLTQLLRFSENK
>A0A834BE97|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Phyllostomus discolor|TrEMBL
MAQQTTSPDTLTVPEVDNLHCSNPWLNEDLVKSLRENLLQHEKSKTARKSISPKLSPVIS
PRNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFV
HSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAAL
TNLQDRAPSKRSPMCNQPSINKATITESWMEWNPYTLLDM
>A0A5E9I6Y4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. CH235|TrEMBL
MPSVSTLTTADTALLVQLSDSHLFAEADGTLLGMNTRESLQKVIELVLEQQPRIDLIVAS
GDLSQDGTLESYQQFRQMTAQIDAPARWIPGNHDEPQIMAQATVKSALLESVVDVGNWRV
TLLDSAVPGSVPGYLQDDQLQLLARALSEAPDRHHLVCFHHHPMSIDCAWMEPIGLRNPE
AFFEVLDRFPQARAVLWGHVHQEIDRERNGVRLMASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGRIETGVERVTDFRFTVDYGSDGY
>A0A851I0P0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter adhaerens|TrEMBL
MNAKEHARPLRVLQLTDPHLMAGADGTLLGVNTRNSLDAVIAEVLHYHGQPDLVLATGDL
AQDGSQEAYHFLGERLGAFNCGSAWLAGNHDDAARLYAIATEYAASQRHIIQGGWQFILL
DSSVPEKVYGELAESELEFLAERLAQNPDLPALVALHHHPVDVSADWMQDIGLRNRDAFW
QVIDRFPQVKAVLWGHIHQNLEQHRKGVRLMATPSTCIQFASGSRDFSVEEQAPGYRWLE
LQASGSFTTEVRRARDFEFELELTSSGY
>A0A8J2W5K5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Daphnia galeata|TrEMBL
MGCATSQLPLGGGSHRQRRHSSSVNSSPPNNVTAMLPDNHHHHNDEKGNHSVLLATNNTI
SQQQQQQQQQALHIVRNPSNSDNRPSSENSTTTGKYRRGTSGEQHNTSSPTLENGVRLSN
DVRFGSMRAPPEPLKMMLIFEREDAQSDAWVWACRKLASRSGGCVGTDMSHSNSRSSHSS
GGSSSFNSSDINHQHLLVRNLQPEFVQRKIAELEPNLIVIDRRSASRTRDVDALCRWIRV
QPGGNYPIILAVVKRNLLEREESTVSSILQIGYDRCYPESGSLGSCLSELLMLENSELQS
RQRLRLAEASMTVTAVTRVVTPFSVELVTVTDGHFNIRYINPGVERLLGFAADEIVGKNM
IELYRCEAGNNRYDINDAAQHVLTNKTREWEGSCFVRRRTGDSVPLYTRMIAVHSTKAEN
ETPDYVLLLQEPPPLFIDKSLSGDMGAYDFYPMPRSSLHSVRKASYDVRSVGSDGAIIRR
QSLARLHSMAIEGPITKVINIITAAQESSPNYISQALDKVLDILRSTELFAPHVAEVKGR
NEDPVTTDLVGALLLGQKQPGYIRRSSNETSLKSSHSQLYSRPLLPSLNNISIPIQLREM
LENDSQWDFDVIRLEKLTGKRPLVWLGMTIMTRFEVPRTLNCDEATLQNWLTVIEANYHS
SNTYHNSTHAADVLQSTAYFLQRNRIKALLDPLDLTACLIAAAIHDVDHPGKTSGFLCNS
GNELAILYNDLSVLESHHAALAFKLTCADDRVNIFKGLDRENYKVIRQSIIDMVLATEMT
KHFEHLTKFINIFAKPFLRQDEDQYEPPEIDYTSLNTQENIILVKRMLIKCADVSNPTRP
LNMCIEWARRIAEEYFNQTAEEKAKGLPVVMPQFDRQTCSIPKSQIGFTDYFVSDMFDAW
DAYAEVPELLQHMKRNYQFWKEQEIMGVTGLPPEHIIPLTPTELVRKIEFETLAECKETV
EPAEDK
>A0A066RPQ0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Photobacterium galatheae|TrEMBL
MQTYSLPQKNSDSVLLLQLTDTHLFADEAGSLLGVATKDSFHAVLDEVAAQSRPFDAIIA
TGDISQDHTPESYQRFAHGIERWAQPCFWLPGNHDYQPSMKSVLPSPQIKACDQVLAGEH
WQVILLDSQVVGVPHGELSPVQLEMLDKALAGEPDRHALVLLHHHPLPAGSRWLDQHQLK
NNDAFWQVISRYPQVKAVLCGHIHQELDVLHQGVRVLATPSTCIQFMPDSHDFALDQSNP
GWRWLALRPTGEIDTQVERVRKRSFSPQFDAAGY
>A0A498QC31|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mycobacterium attenuatum|TrEMBL
MHRLRAAEHPRPEYVLLHISDTHLVGDDGPLYGAVDADGRLGELLEQLTSSGICPDAIVF
TGDLADTGEAQAYRKLRAVVEPFAAELGAQLIWVMGNHDNRAALRRFLLDEAPSMAPLDR
VHMIDGLRIITVDTSVPGHHYGELRSSQLSWLAAQLATPAPHGTILALHHPPVPSVLDLA
VTVELRDQAALGRVLDGSDVRSILAGHLHYSTNATFVGIPVSVASSTCYTQDLTVAAGGT
RGRDGAQGCNLVHVYQDTVVHSVIPLGGGKTVGTFVSPAQAKREISESGMFIEPSRRDSL
FSQPPMVLTPVAPSARVD
>A0A498PRB0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mycobacterium attenuatum|TrEMBL
MSGDPRAMSRRQLIRHTAWFGAAVGFAVCGGEVISHVAGAAEAPSAAGRPALRFAQISDS
HLGFADEANHDVAATFGQAIDRINNLGYTPDFVIHTGDLTHLSTPDQFDQVKQMVTGLRT
SHVFTVPGEHDSIDDAGQKYRNAFGAGTRGDGWYSFDIAGVHVIALVNTLNMDKLGHLGV
EQLEFIEKDVARLSSDTPIIVMSHIPLFAMYPDWGWATDDAARALGYLRRFSSVTCLNGH
VHQLFSKTEGNVTFYSGTTTAYPLPRPGDGPTPKPVTLPARQLGAVLGIREVSYTRAQHP
LALKERSLQ
>A0A4U0YMJ2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Halopseudomonas bauzanensis|TrEMBL
MSPPATITSTAAVQVVQLTDSHLFTAPDQRLLGLDTLASLHGVIDQVLEDMPQIDLVLAT
GDITQDGEEPAYQRFIEAMTRLPAPWHWIPGNHDDAARMAQLGAGHDFNQPWVDAGAWRI
VLLDSSVPGSVGGHLDERQLLRLDEALATAGERYLMVCLHHHPVPIGSAWMEPLGLDNSE
QLFARLDADSRVRVVLWGHIHQYLDQQRGHIRLLASPSTCVQFAVGSDDFATDAQPPGYR
WLRLHGDGRVETAVSRLPAGCFVPADGASGY
>A0A5D3I4E3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Moorella thermoacetica|TrEMBL
MKKFAALFLAVVIAVTMLAPAASSAAGTPQYDLGASAQPDHITLTWTQDPLTTQTITWRT
DITIARGLVQYAKAADKASFPGKAATVEATVQKFTSDLGDMNIHTATLTGLEPGTEYIYR
VGDGTNWSDIHTFTTEASNTHSFKFLIFGDSQSGDPLNPEYKPWHDTIQNAFKTNPDAKF
FVNVGDLVEQGQNYVHWNKWFEAAKGVIDTIPAMATQGNHETYNPPDGHSTKPIFWTTQF
KLPQNGPEGLKGQAYSFDYGNAHIVMLDSQEEEEKGVAGDILAAQKAWLEKDLQNTNKPW
KLVFFHKTPYYNKATRTNEDIKAAFQPLFDKYHVDVVFNGHDHAVARTYPIAGDKFVSSP
AKGTIYYLTGRSGNKYYPDLSAKVWDAFFYDPQDQPNYIVAELNGDKLTLRAMKQDGTPI
DTYTIDKASGLDTPQTIVPPKYNSTRLVIFGNMLQQPLLPVTPKQVNGQWYIPVRAFMQF
LGGNVAWYDDGSVTIVYGKDKVQMASNSARATINGQEVNLPGSSLMDKNTLFIPAADLEE
FFGFSYKYDAATNMLMFTK
>A0A4R6DAY7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Haemophilus haemolyticus|TrEMBL
MKNTFVYQAEKPVIKLLQITDPHLFKDERAELLGINTQASFAQVLKEIQQENNEFDVILA
TGDLVQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQSPMDEAKHLLLGEH
WQALLLDSQVYGVPHGQLSQHQLDLLKEILEKNPARYTLVVLHHHLLPTNSAWLDQHNLR
NSHELAEVLAPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQP
GWREIELHSDGSICTEVKRIQQAKFLPNMQEEGY
>A0A5C1AS91|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Limnoglobus roseus|TrEMBL
MLTRRGLLAAAPLAVFTAAFPKATAAVPSTPLRFGIITDVHHDLVPDGVARVTAFADAMT
AGKVDFVCQLGDFCTPKPANRPFLAAFERFAGDRYHVLGNHDMDGGFTREKTVAFFGMPG
RYYSFEKAGVRFVVLDGNDPGGKTKGYKRFIGKYQLDWFAKELATAAGPVVVLVHQPFDD
QPFEAIENHAEVRAVLKAANAKGPKVAAVFSGHHHMNYVQKIDDVPHVQVNSASYYYLGA
HSHMSYDAETHKKYPVLAGTCPYKDALWAVVTIDQTQGKLTIEGKSTEWLGGSPWDVGAK
ETAHDPKMVQPMISPQEFAVARANRK
>A0A3B7M7T5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Acinetobacter sp. WCHAc010052|TrEMBL
MTSSALTPRQQSWTIIQITDTHLMDQEDLDFVSINPEQTFKAVIQDIMEQYPEADAIIHT
GDLAQVPVVSTYERYINFMETLNVPFYQIPGNHDNAECFPFYDYKDEIHTIQLGKWSICL
MNSAVKGKVDGWVEQAQLEQLNQILQDYQDQSIVLACHHHPFEMKSRWIDNHKLKNTEQL
TDILGQHNNIKAVLFGHVHQDSLHEWNGIPFLSTPSTCVQFKPLSEKFALDEQAPGYRVM
HLHENGRFETRVHRISGLIQKINGEISGY
>A0A7I6RUB6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella sp. WP4-W18-ESBL-05|TrEMBL
MESLLNLPLAGGASVRVLQITDTHLFAEKNETLLGVNTWESYHAVLQAIHASARDVDLVV
ATGDLAQDHSAAAYQHFAEGIASFTAPCVWLPGNHDFQPSMYSTLQDAGISPAKRVLVGE
HWQILLLDSQVFGVPHGELSDFQLEWLEKRLAEAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAASLDTVLVRYPRVKHLLCGHIHQELDVEWNGRRIMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHADGSLTTDVCRLAGVKFHPDTASEGY
>A0A5I3TAH6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Stanleyville|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A4Y7ZW63|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Psychromonas sp. RZ22|TrEMBL
MNGVSQTSTTITADLNGDIKLLQITDTHLFADPEKDLLGIKTVKSYDAVVKHAHQYAGRC
EAVLCTGDLSQDHSIQSYTYFSERIKSLKMPCYWLPGNHDMQSVMLPSLLQEGLAQSKQI
VSEHWQIILLDSQVEGVPHGLLSESQLIFLTEKLQEYPNKHALISVHHHVLPVGAAWLDQ
HILKNNKQLRALIKPFTNVKAVLSGHVHQAFDMTKEGVRYLTSPSTCVQFKPKSYDFAVD
TQAPGYRYLVLTKEGDIITQVERINANEFTTDENATGY
>A0A6A7SJ53|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|wastewater metagenome|TrEMBL
MESTNDDGAHGLAFAHLSDPHLTSLRALRRRELIGKRLLGYLSWRRGRRHAHCDGILAAL
QRALASHPDEEIAVTGDLTHLGTPDEYREARDWLAALGPGPQVTVVPGNHDLYVPVRWQD
TLAEWAAHMCGDGDERPRFPFERRRGPVSFIGVNTAYPSAPLLATGRIDGDQLDGIGRAL
ARAGEAGRFRVVLMHHPPQPDAVSRRKSLVAAERFRALVRRHGAELVLHGHAHRRLRGEI
DGPRGPVPVLGAPSASQRTHDPARNAAYHRCVVTPTPTGWRLGVTVHAYDAETGDFVPRA
DAGGTLEIPRQSA
>A0A091HRF0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Buceros rhinoceros silvestris|TrEMBL
FDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSS
LPSEQHGDDLIVTPFAQVLASLRSVRNNFTLL
>A0A7Z2Y208|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. ADAK7|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEADGTLLGMNTRESLQKVIELVRQQQPRIDLIIAS
GDLSQDGTLESYQQFRDLTRQLDAPARWIPGNHDEPMIMAEAAVQSALLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPDRHHLVCFHHHPVSIGCAWMEPIGLRNPE
GLFAVLDRFPQVRAVLWGHVHQEIDQVREGVRLIASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLMPDGQIETGVERVTGFDFTVDYGSNGY
>A0A2I0TN78|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Limosa lapponica baueri|TrEMBL
MPSVLMPPHSRRGPRGRVLAEPCGGARAEKVKGNSANAGVEKNVSVEDAVWAAKRGTFKR
MLNRELTHLSEMSRSGNQVSEYISNTFLGKNKVTQAQLHPLIFATTASYGCIFPLQRQGS
DKQELEDLNKWGLNIFNVARYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLED
HYHSDVAYHNSLHAADVAQSTHVLLSTPALDVLRNMVHCADLSNPTKSLELYRQWTDRIM
EEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILD
TLEDNRNWYQSMIPQSPSPPLEERGRDCQSLMEKFQFELTLEEEDSDGPEKDGESIAYFS
NTKTLCVADPGEEDSQREANIEIVTEDTSPVDT
>A0A8J6RQY4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trichocoleus sp. FACHB-832|TrEMBL
MIPAKPLAIAQITDIHLFADTKKELLGLPTEKSFHAVLGQLQKLLPQLDMLLLTGDLSQD
GKAESYQRLAELLSPLSIPTYWAPGNHDQPFVMQQVLKEAPISPEKSFAAGGWQFLLLDS
HVSGCVHGKLSSESLVWLDTQLKLASDRPTLIGFHHPPFLVDSDWLDGSTLQNPEELFAV
IDRHPQVKLVIFGHIHQEFYQRRGGVHYLGSPSTSIQFEPHSHNFSLDEVEPGFRLLNLY
PDGSFETRVQRVTYVHELDLAATGY
>A0A7J0B4A7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Muribaculaceae bacterium|TrEMBL
MLRTFLQNIRNTILKRQNEVVHFKFELGTSFHPETGFFEKEHPECMADFRFYQVSRGDRV
ICRNSAYRYGIASFGAEIEERLIYTYCYQEEENWSAYLGDFEPDCLKSGNSAVLQDGWIR
IAVKRVDGAALTCEDINAVTEGMALIRRRQTYKEKDYFKQEIEQTIQAVNEKREQDSLVF
GLMADSHYVINGGWEDSIANLQAVNRKAPFDAMIHLGDLTDGMVPLAITREYAVKVMEDL
HSLKVPVYLTLGNHDSNYFRSNPEWLNEKEQSFLYLGKEEPWYYVDFEKQKLRCLFLHSF
NHREKIRYGFSMEEVEWVKQVLAQTPDAYRVLVFAHVPLLPEMHFWTKEIRNSKEMLEAL
EEYVQQGGKILAYIHGHNHADQIYYGKRFPIVSIGCAKCEDFKDKKPEGAVTYDRKMKTL
TQELWDVMIVNGKKDEIEFIRFGAGEDRRILC
>V1GRN3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. indica serovar 6,14,25:z10:1,(2),7 str. 1121|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLVNFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A2Z4AGV4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Moanabacter tarae|TrEMBL
MTFIEVIAEVQSLNPDLLALTGDIIHFPSQANLDHVTEALIGLNTPILYTAGNHDWYFPG
VDARG
>A0A1Y0L4H1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Tatumella citrea|TrEMBL
MDSVLVPGIADDSQIRVLQITDTHLFKGKDESLLGVNTWSGYQAVLDAVIAQQQHYDLII
ATGDLSQDHSVEAYQHFAEGVQRFTAPCVWLPGNHDFQPAMYDTLAKAGISQSKHVLLGQ
RWQMLLLDSQVYGVPHGMLSEFQLEWLEKALAAYPDRDTVILLHHHPVASGCSWLDQHSL
RNSHQLDMILQKYPRAATLLCGHIHQEMDEIWQGRRVLATPSTCVQFKPHCSGFTIDSVA
PGWRWLTLGADGQLTTQVCRLNTREFLPDLESEGY
>F9RHD8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. (strain N418)|TrEMBL
MKVTSSSSAKDTIKLVQITDTHLFAAEDGSLLSVNTNDSFSAVVEAVTQQDFDFDAILAT
GDISQDHSDVSYQRFAQGIEPLKQPCFWLPGNHDYKPSMGSILPSTQIVQAEHALLGEHW
QMILLDSQVEGVPHGRLSQQQLDLLDEQLSLHPERHSLVLLHHHPILVGSAWLDQHTLKD
AEQFWQVVEKHDNVRAILCGHVHQDMQKVRSGATVISTPSTCVQFKPNSDDFALDTCSPG
WRELTLYADGQFETHVQRLAGGLFLPNFDSSGY
>A0A839WDW2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Atlantibacter sp. RC6|TrEMBL
MESLLNLPVADGASVRILQITDTHLFAQKSETLLGVNTWSSYQAVLEAIAAQQRPCDLIV
ATGDLAQDHTPEAYQHFAQGIAAFSAPCVWLPGNHDFQPAMFSALQEAGISSAKQVLCGE
KWQILLLDSQVFGVPHGELSEYQLEWLEAKLAENADRFTLLLLHHHPLPAGCSWLDQHSL
RNAGELDAVLGRFPNVRHLLCGHIHQELDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGTVTTQVERLEGTQFNPDTASEGY
>A0A737F5X2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella gallinarum|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A399EBT5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Calidithermus terrae|TrEMBL
MRIAVLSDIHGNLPALEAVLADLEEVRPEVVVVNGDLINRGPQNRAVVERLWELPYRFTL
GNHDDLVVKWRAGHDSLRLLFDDPFFAATRWTAHTLPQPHLDWLAALPYQVHLEELGLRV
THGSPRHYREGYDERLSEQALGEILREYPARYLVGSHTHRPYVRRHDGALVWNTGAVGAP
FNGDVRAQYLVLEAEAGALVPHFRQVPYDLEATLKAFRESGMLEEGGLSAEIFYCETQNA
RSMLVPFWLWAEAEKRPLDRDAWAAYRRANPERFARSG
>E9XGP2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli TW10509|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDNVLAKFPNVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A5C5P0X6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas rhodesiae|TrEMBL
MPSVSTVSPDASALLVQLSDSHLFAEGDATLLGMNTRESLQRVIELVRKQQPSIDLMLAT
GDLSQDGTLESYQQFRALTAAIDAPARWIPGNHDEPLLMAQAAEHSDLLEPVVDIGHWRI
TLLDSAVPGSVPGYLEDQQLQLLAQSLSEAPDRHHLVCFHHHPVSFGCAWMEPIGLRNPE
ALFAVLDRFPQVKAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHADGSLETGVERLKDFAFTVDYGSNGY
>A0A2K6DDC7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Macaca nemestrina|TrEMBL
MRSGAAPRARPRPPALALPATGPESLTHFSFSDEDTRRHPQGRSVSFEAENGPTPPPGRS
PLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPF
AQVLASLRSVRSNFSLLTNVPVPTNKRSPLGGPTPVCKATLSEETCQQLARETLEELDWC
LEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIP
SPTMKEREKQQALRPRPSQPPPPPVPHLQPMSQITGVKKLMHSNSLNNSNIPRFGVKTDQ
EELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLT
LEDHYHADVAYHNSLHAADVLQSTHVLLATPALDSELALMYNDESVLENHHLAVGFKLLQ
EDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDN
YSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHT
ASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEES
RGPGHPPPPDKFQFELTLEEEEEEEISMAPIPCTAQEALTAQGLSGAEEALDTTVAREAS
PAQESLDVMAQDESLEAELEEVYLTQQAQSTGSAPVAQDEFSSQEESVVAVSQSSLSSLA
LQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACTGTSGEDTSALPA
PGGGGSGGDPT
>A0A7T0RUG5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio navarrensis|TrEMBL
MQHTTSDTSSIKLLQITDTHLFATDEGSLLSVKTLQSFQAVVEQVMQRQVAFDYVLATGD
ISQDHSAHSYQHFAKGIAPLQKPCFWLPGNHDYKPNMSSVLPSAQITAPEYVALGEHWQM
VLLDSQVVGVPHGRLSDSQLILLEEKLASNPSKHTLILLHHHPLLVGSAWLDQHTLKDAE
VFWEIVYRYPNVKGIVCGHVHQDMNRMHRGIRVMSTPSTCVQFKPNSDDFALDNVSPGWR
ELQLHADGEITTQVQRLSAGSFLPDFTSSGY
>A0A6B2IKP2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. SE1|TrEMBL
MLKEAITYGIPEDKSVRLVQITDPHLFAEPEGQLLGVNTANSLNAVINTIQAVKYPADML
LASGDISQDYSGESYRNFVEAIKPLNLPCHYIPGNHDDPRIMYLHMQGERVYGHRRVLAG
NWQIILLDSTVRGKPGGHMAESEIEIIRSAIAAEPDRHVLLVMHHNPVLVDCTWLDQHCM
DNGAQFLKEMGSYPQIKGMLWGHVHQQLDTEYQGEGHKLSLMATPSTCIQFKPLSSYFAL
DALQPGYRLLELKPDGSMLTNVYRIPGERFAPDAEASGY
>A0A5E4K342|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MKILALGDPHGKLPKNLDSLIKKNKVETIICTGDFAFTPDKPWLKESWKGISDSFVIKSY
KKVVDELCSYGIPLLTLRGNMFLNKKKIADKILRKHKNLINRYTAKYKLNHEEFIFFDLS
YELSTLMKDQKQDIFFKSRLKKNNGREKRLNELLKENSNSILITHNPPYGVVDKAWNGEH
VGSKILLNAIKKYQPKYVFCGHIHEAKGRAKIGETIIYNLGCRGDYIILDTDKNKIVTSN
F
>A0A5E4J023|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|uncultured archaeon|TrEMBL
MASYQIFHLADIHFKDTRRQEYSEILSKLYLSIKQHQKLDKEHTLICILGDIFDTQTRAS
GYNIQDVSNMFVELSKFGSVIIIPGNHDFSVRNVERYLDLITPIIDILKLTHPNIYYYSE
SGMNRFNPNITFTILSPKDTFKDNIEPYIPCDNFHICLLHDEIKAPNFHLSEPHIPIEKI
KGYDLVLCGHIHKRVFLSEKIAYSGSLIQQDLGEDPTEHGYIIWNIDTRMKQVSYELINI
PNDYGYLKLSMKDNQLLTRNVFKRLHKFTVSFENCSPEEVNEVIRTYNKISEIKTKPIPE
ITMTRISEQPRTISFEELVLSKIKDTSSSEKVLKLHNEFRREVITETNHGLWTPTKLELS
GFLYHKDEKVINFQNMLGKIGGIIGKNHTGKTTILNALMLVAYSNMNGINKKDIINHDSN
ESRIKLEFECDGKKGMIERKDRNSKKSNVSFVFDDKNLGNKIKDTYSEIGSYLGSYEMAS
NMNFIVQGSYQLVATMSQLDLKRFLISLFNLEEFQMILKRAKSEALDIQKEIKGYKTGIQ
CENDMTLKEFRHETKKDIKRNRKLVEKYENVVRDMKEKLEMIKFKDGISVSETKIDELFE
TLRDLYEKYPHCLDNLHLGRDKLLKINEFYSKNQSEIDKITETLPELREKYEQTIKQIKK
LTPISLDEYKRCVRFVENYGKMDESKVRHVVRPEKLYDSPRESEISDWKFDKNEFNYDEK
LEKRLLNELEEYKNEYRLIENDALPDDNWNNEMISRLRMISERLRELGTRQKMNVSEQQY
KESLRFIDETNVIDVSRDKYKFSRDTKFSLNEFKSERCREIDDVRGLVCEKFGEYEGEIE
LHDVKYDRNKERILVGQIRTGVESEETLEKMRVIDRKIPDVMFEKECGLYFDIKQICEEI
KNLGIIEKYDEVKQDEYERARKFLKETSGIDVSKDKFKFGDKIEFRLDEFISERCREMRD
DEQWMKCWNGCWIDGMNDDETEGWSEDWSEVDLRVGKIVDRKIPEVICEDKRELVERIRE
HLNDVDAEDVRAKVRMKKMLGDVKFNKDCPTCKMIRKLLKVEENDDLVDVQKLIEEYNSH
VDKKVRGYLRMIYKQNGMYNDLKEKVGLNVSMVRNYEMMMRGRRLEGYEKKLDSKISEYN
KRIDEELFKSKRQKEIQNELKENNKDKDEYQKMCNYLWYVSESNGMYNDLKEMSKKVREN
VRDYEIGELVREKERLVDEYNKKVVGWREKKKELEKVVSDKDEKMRYDLMRNYVWYVSEV
NRMKDDMNDYLKLKEKDEIKRKIDVIEGMVKDSLVCVRMLEIGGELSLKCNEKIEKDTKK
MSECEKECERLEEIMSGIDEMIEKEERLELVKEYIKLINPRDEDEVILDMLKEKSQGLIV
RINEILGETNETMRVSIDDDYNIYVDGILARYSSGSQKFIFELCLRLAMIEIGSRNCMNG
IIIDEGFGMLDSENLEGIKRMLVKLKKAGRLIVIITHVEEMKDIMETVEETS
>A0A8C3NMT4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Cyanoderma ruficeps|TrEMBL
MLPTTHCSPGASPAASPRGSPRNSPVFFRKLLMSQSIRLQRRFTVAHPLCFDLENGPPGR
GALDPQASPGAGLVLQGTFSHGQRRESFLYRSDSDYDLSPKAMSRNSSIASDLHGEDMIV
TPFAQVLASLRTVRSNLTHLQDRAGIKRGSSSSLPSGSKASLSGECRGNGGGEILGRAGC
RCVPRVCPAVPWGCSNSPPPPQAKAELRLCPSGSMSGFRQLLPPGRPSRRWKSSR
>A0A1V4B0L7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Canicola haemoglobinophilus|TrEMBL
MISAYQYNTSEKVVRLIQITDPHLFKDKNGELLGINTHDSFNQVLTEASQSQFDYELVLA
TGDLVQDSSEEGYQYFAKAISALQKKVFWIPGNHDFQPKMFDVLGQYQEYICPTKHVLVG
DKWQILMLDSQVSGVPHGQLGQYQLDWLSAKLKDHPERYSLVVLHHHIVSTNSAWLDQHN
LRNSLDLMEVLSPFRNVRGILYGHIHQAVDTELHGYKIMATPSTCIQFKPDSNNFALDTL
QPGWREIELYDDGRIETRVKRIQQATFLPNMLSDGY
>A0A1D8JZP9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Klebsiella sp. LTGPAF-6F|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFTAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQVLLMDSQVFGVPHGELSDFQLEWLEQKLTEVPQRYTLLLLHHHPMPSGCSWLDQHSL
RNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A4V1UE12|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Chitinophagaceae bacterium|TrEMBL
MTFQVSTLSQQDFVMIQITDTHLLEYPHLEFVGMQPEQSFHAVIDLMRQQHPHIDLIVHT
GDLAQTPSPVTYHRYLQHMQSLAIPFFQTPGNHDDVAHFPFHEENPTQPTVVELGKWRII
LLNSAQPERIDGKISELQLKQLTELLTQFDDCYVIIACHHHPFTMQSAWIDQHKLKNSSD
LLETIKPFSNVKAIVCGHVHQDSIHTWQGIEFLSTPSTCIQFKPKSDKFALDEEHPGYRY
ICLKANGELETQVYRLSCSQRMNSSEVLGYD
>A0A5Y3MNY8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. salamae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAAKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A7L6DMC9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Citrobacter sp. RHBSTW-00903|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWDSYQSVLDAIHAESPEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERNTLLLLHHHPLPAGCSWLDQHSL
RNAAELDNVLVNYPRAKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIS
PGWRTLELFADGTLQTQVRRLQGNRFHPDTASEGY
>A0A1A8QST1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nothobranchius rachovii|TrEMBL
MGVVETIDPEPSPCASPVPGGYRLPRSSSYSPLQGRPGAELDLGAADGGVMEGGGTAAER
RTPLVDLFCETCSRPWLIGWWDQFKRMLNRELSHLSEMSRSGNQVSEYISTTFLDKQNEV
EIPSPTLREREKPMCHISGVKKLTHSSSLSNSTMPRFGVKTEHEEALARELDDLNKWGLN
IFHVAEFSNNRPLSCIMFAIFQERDLLKTFRIPVDTFVTYVMTLEDHYHANVAYHNSLHA
ADVTQSTHVLLSSPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYND
ES
>A0A7K0D0J4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Nocardia macrotermitis|TrEMBL
MILLAQLSDTHFDLKNRNAERVERVLAYLSALPRQPDAILLTGDITDAGKPEEYEQARDT
LRAISIPLWMLPGNHDDRAALRRILLHEDASDRPLNQAMRLHGLTVALLDSTVPGASGGE
LDDDTFAWLTDLLRTTPPDDAVLIALHHPPMPMYSTVVDPIRLSNPERLERLVAADPRIL
GVLTGHMHTLGTTLFGGKPLIVAPSVASTIGGAWEVTTPGEVPIDYAPDPAILLHVIDDG
RFTTLLRPVPMGGRIAAV
>A0A3S8URG6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas entomophila|TrEMBL
MPQALFAESPVHVVQLTDAHLFAAPAGTLLGLNTRDSLEHVVAQVRREQPRIDLLLCTGD
LSQDASVASYEAFRGLTAGFGAPARWLPGNHDEAQVMAKVAPELITAVTDIGAWRIVMLD
SAVVGATFGLLAEDQLATLDQALATAGERHCLVCCHHQPVDIGCAWMAPIGLRNADQLLL
RVKAYPQVKALLWGHVHQEWDQVREGVRLLATPSTCIQFAPGSEDFQVSEEQPGYRWLRL
HADGRLETGVERARDFVVKLDFDSPGY
>A0A7L4X2B0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Shewanella sp. YLB-09|TrEMBL
MLKEAISYSLAAGASVRIVQVTDPHLFADPSAQLLGVNTALSLESVLNTIKAVQYPADFM
LATGDISQDYSGESYHNFVRAIAPLDFPCHYLPGNHDDPRIMRLNMQGPNIYGQQRILAG
SWQIIMLDSTVRGKPGGHMADSEIDLIKSAVADQPDRHTLLVMHHNPILVKCQWLDQHCM
DNGSDFIEQVSQIPQVKGLLWGHVHQQLDKKHLGPHGAISLMATPSTCIQFKPLSSYFSL
DALQPGYRLLELKADGSMLTNVYRVPGDKFFPDRGARGY
>A0A2V2BJV5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pantoea allii|TrEMBL
MDSLLTLPATTGSEFRILQVTDTHLFAGKHESLLGVNTWSSYDAVLDAIIAQQCDYDLIV
ATGDLSQDHSVEAYQHFVEGISRLPKPCVWLPGNHDFQPAMVDTLAKAGINTHKHVLMGE
HWQVVLLDSQVFGVPHGMLSDYQLDWLHNALARFPLRHTLVLLHHHPLASGCTWLDQHSL
RNPHQLDAVLQHYPLAKTLVCGHIHQEMDVDWHGRRVLATPSTCVQFKPHCTSFTIDTVA
PGWRWFTLHDDGQLETEVNRLTTQAFCPDLDAEGY
>A0A223ZI65|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Methanothermobacter sp. EMTCatA1|TrEMBL
MEKKIAQISDVHFGEKNFSDQLRNNLLRQLENENPDLIIVSGDLTTEGYSHEYELAAAFV
DELRTITSTYTIPGNHDARNVGLIHFEKLIGRRKFVHHDSGFAVIGLDSSEPDINDGQIG
MDQLEWLRKELERVPDHLCKIVTFHHHLLPIPNTGRERNILLDSGDLLKLLKEYGVDFVL
NGHKHVPNVWMIEGMVTLNSGTATTRKLRGETFPSHNQLRINDDRISVDLINTESGSVRE
IASYSVRVEDEEYRICSYMHSI
>A0A1Q9PEQ6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Heimdallarchaeota archaeon AB_125|TrEMBL
MVKILLLSDIHSQNITLINILKVVKKLTNPPENCLIAGDITNFGTTEELNKILNIITDYF
SKVFFVLGNCDPFVRTEELETSAKHLESNIQGIEFFKVVGFGTHKPKLNQKVLNKLRKSK
ERVCLLTHAPPYNTQADMVSLNKHAGSVDLRNFIEKNSHIFLVISGHIHDSPTLTKLNNC
TIVNPGPVTTGNFAILDIHQDFRVDGKIHNLYEV
>A0A0K9TI98|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Escherichia coli M114|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A509MQL1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Marinobacter halodurans|TrEMBL
MPSPVLSDKQPSVPLRVLQITDPHLMADPEGVLLGMNTRESLEAVLALAAGAEDHEPDLV
LASGDISQDGSEAAYRLFQRLMSGFKCPVIWFPGNHDDAATMRKVTAGSGADERRVLAGG
WQVICLDSSVPGQVHGELADDELDFLGRCLAEYPDTPTLVTFHHHPVDIDCRWMADIGLV
NRDTLYQTLSGHSQVRGLLWGHIHQAWDDERDGRRLMATPSTCIQFAPGSNDFSLDDKAP
GYRWLELYPDGSLASHVRRAEDYAYTVDLDSHGY
>A0A0C1Z0T1|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio owensii CAIM 1854 = LMG 25443|TrEMBL
MQSSSDSIKLLQITDTHLFEADEGSLLSVRTADSFAAVIQEVLHRQVQFEYVLATGDISQ
DHSAESYQRFAEGIAPLKKDCFWLPGNHDYKPNMGSVLPSPQIQAVEHLMLGEHWQLILL
DSQVVGVPHGRLSDQQLSLLEEKLAENPQRHTLVLLHHHPLLVGSAWLDQHTLKDAEAFW
QVVDRFENVKGILCGHVHQDMNVLYNGIRVMATPSTCVQFKPNSDDFALDIESPGWRELE
LHSNGDITTEVNRLPDGQFQPDFTSNGY
>A0A2S9YFT5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enhygromyxa salina|TrEMBL
MSTDTNPNSCPHPQLLTTCVAVLLAGITPACADLGENDPDALLVEDQLDDDIGDEPDGEL
EDLGEPDVGSLQAPEASTAPVVSNRDLTFAFVADPQLHGDVADKGGKEQLLLDIQAEVPE
LDWIDGDQKQMEFLLVGGDLTNQLECDEWRDYKDLFKPGRNPDIDFSVYQVPGNHDHYST
NYCPSEVMYIGGTAWHQTKNQQRQYIRENQGRHPSIGRHGYLAKPSQAAVTDYNQDISFA
FETQGVYFVGLDVADNSDQDVIAKSITFLTNRLNQVGPEEPVVIFQHFGFDAFSESWWSD
AEREDYLEALDDHNVVAILSGHMHSGVDDDGALRQPSAHDPGASLGVWTNDPGRVEFNNG
GAEQFFELRDYKGGAFFNHVGAWVFHVTDEYFEAKRLDAGQSTMSEIASFRMKIPTNGTA
DFVERFHNNASFSHWDQHAQTNEGAANWAIYNEDGNNHGNVLRATGNAHSTVAGHTGQDV
ATWGTWMVDPSTRFGAGELSVQIKVEDDDAFGLMYAITDEDNYYRVLINHQFSYARLVAV
EGGQFSEIASNTWNGDVQGQWTDLKIVRSGSNHKIYLGGALLLDANDDTFPTTDSGAVAM
VTAGMADMRYDRLMIRQ
>A0A1J5KN84|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Vibrio sp. MedPE-SWchi|TrEMBL
MKLSSNTADSEAIKLLQITDTHLFAPEDGSLLSVQTLDSFHAVVDMVEQSAVKFEAILAT
GDISQDHSVESYQHFAAGIAPLKKPCYWLPGNHDYKPNMGSVFPSAQIEHLEHVLIGEYW
QIIMLDSQVVGMPHGRLSDRQLALLDDKLTENPDRHTLVLLHHHPVLVGSAWLDQHTLKD
SEQLWQIINKHSNVKAILCGHVHQDMDREVNGVRVISTPSTCIQFKPNSDDFALDKCSPG
WRELDLHSDGQLVTKVQRLPNDSFLPDFTAGGY
>A0A378GFH0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Kluyvera ascorbata|TrEMBL
MESLLNLPLAGGASVRVLQITDTHLFAKKDETLLGVNTWESYHAVLQAIHASARDADLVV
ATGDLAQDHSSAAYQHFADGIASFSAPCVWLPGNHDFQPSMYSTLQDAGISPAKRVMVGE
HWQILLLDSQVFGVPHGELSDFQLEWLEKRLAEAPERHTLLLLHHHPLPAGCSWLDQHSL
RNAASLDNVLVRYPRVKNLLCGHIHQELDVDWNGRRIMATPSTCVQFKPHCANFTLDTVS
PGWRWLELHADGSLTTEVCRLAGCEFHPDTASEGY
>A0A6P1S139|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pectobacterium polaris|TrEMBL
MESLLTLPVASGARVRILQITDTHLFAGEHETLLGINTYRSYHAVLNAIKARQDTFDLIV
ATGDLAQDHTLQAYHHFSRGIAQIPAPCVWLPGNHDFQPAMVDALADAGIAPSKHVLLGD
KWQIILLDSQVFGVPHGELSEYQLEWLERSLKSQPERFTLLLLHHHPHPSGCTWLDQHSL
RNAHNLSTVLERYPQVNTVLCGHIHQEMDFDWHGRRLLATPSTCVQFKPHCTNFTIDDVA
PGWRYLDLLPDGRLETEVYRLSGSEFLPDMDSDGY
>A0A5E6QX61|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEADRALLGMNTRDSLQKVIELVRAQQPRIDLILAT
GDLSQDGTLESYQQFRDMTRQLDAPARWIPGNHDEPQIMAEAAVQSALLEPGVDIGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFEQVRAVLWGHVHQEIDRMRNGVRLIASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGRLETGVERVTGFDFTVDYGSNGY
>A0A8H2RVR6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPQPIQPSESSPVHVLQLTDSHLFADAQGSLFGLNTRDSLRHVIAQARREQPRVDLLLAT
GDVSQDGSEASYAWFRQLTEPLGAQARWLPGNHDDRAAMARTAQGADLLQEVTDIGRWRI
IMLNSQVVGATFGWLAEGQLASLDRALREAPDQHCLIAMHHQPVPIDCAWMASIGLRNAD
ALFTVLEGHPQVRALLWGHVHQEWDQQRGGVRLLASPSTCIQFAPGCEDFTVSEQKPGYR
WLRLHADGRVETGVSRAEDYEVRLDFNGPGY
>A0A5E7TCP6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MLTTADPALLVQLSDSHLFAEANGTLLGMNTRESLQKVIELVLGQQPQIDLILATGDISQ
DGTLASYQQFRQMSAQIAAPARWIPGNHDEPMIMAEAAVQSALLESVVDIGNWRVTLLDS
AVPGSVPGYLQDDQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPEAFFEV
LDRFPQARAVLWGHVHQEIDRERNGVRLMASPSTCIQFEPGSDDFKVGEQAPGYRWLRLL
PDGRLETGVERVTGFAFTVDYGSEGY
>A0A5E7IR67|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADSALLVQLSDSHLFAEADGKLLGMNTRDSLQKVIELVRLQQPQIDLIVAS
GDLSQDGTLESYQLFRDLTRQLDAPARWIPGNHDEPRIMAEAAVQSALLEPVVDVGNWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCFHHHPVLIGCLWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEVDQVRKGVRLIASPSTCIQFEPGSDDFKVGEQAPGYR
WLRLLPDGQIETGVERVTGFDFQVDFGSNGY
>A0A8E3CGP2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEADGTLLGMNTRESLQKVIELVLRQQLRIDLILAT
GDLSQDGTLESYQQFREMTAQIDAPARWIPGNHDEPQIMAQAAVQSALLESVVDVGNWRV
TLLDSAVPGSVPGYLQDDQLQLLARSLSEAPERHHLVCFHHHPVPVGCAWAEPIGLRNPE
AFFDVLDRFPQARAVLWGHVHQEIDRERNGVRLMASPSTCIQFEPGSHDFKVGEQAPGYR
WLRLLPDGRLETGVERVTDFQFTVDYGSEGY
>A0A5E6QSA2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MNRPFLIAQISDLHLKADGRLTYGVVDTLGALRRAVEHINASKQRPDIVVISGDLVDFGR
ADEYAVLRPELERLQMPFYLVPGNHDDREHLLAAFADHVYLPLSADGPLDWVVEQHPVRL
IGLDSTIPGEHGGQLDYCQLDWLNAQLSRRPDVPTVIILHHPPFMSGIGHMDHKPFGHAM
ELERVIARHPQVERLLCGHLHRPMQRRFGGSLTCVCPGTSHQIVLDLDEAAPAHFNLEPA
GYVLHRWHPQEGLVSHNAVFGEYEGPYPFYDANGLID
>A0A5E6U0G6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MSSVSTVSPDSPALLVQLSDSHLFAEAEATLLGMNTRESLQGVIALVRTQQPRIDLVLAT
GDLSQDGTLASYQQFRDMTAPIGAPTRWIPGNHDEPQIMAHAAVHSDLLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDSQLQLLAQALSEAPGRHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEAFKVSDQAPGYR
WLRLHADGRLETGVERLQGFTFNVDYGSNGY
>A0A5E7Q270|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEANGTLLGMKTRDSLQKVIELVQLQQPHIDLVIAS
GDLSQDGTLESYQQFRELTQQLDAPARWIPGNHDEPQIMAEAAVQSALLEPVVDVANWRV
TLLDSAVPGSVPGYLQDEQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDQLRKGVRLIASPSTCIQFEPGSDDFAVGEQAPGYR
WLRLLPDGQLETGVERVTGFDFQVDYGSSGY
>A0A5M8F1U0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas veronii|TrEMBL
MPSVSTLNPDAPTLLVQLSDSHLFAEADAVLLGMNTRDSLQRVIDLVREQQPRIDLLLAT
GDLSQDGTLASYQQFREMTAPIGVPARWIPGNHDEPQVMAHAAVHSDLLEPVVDIGHWRI
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPNRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVKAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFNVSEEAPGYR
WLRLHADGRLETGVERVKNFAFTVDYGSNGY
>A0A1Q8D4N6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Aeromonas sp. YN13HZO-058|TrEMBL
METELPQAQDGSVRLLQITDTHLFASAEGRLLAVRTAESLAAVLEQVQANEHPYEVILAT
GDLSQDHSPESYQRFASMMAPLGRPIYWLPGNHDDSPLMTEYLHAAGISESKQLVGDHWQ
VILLDTQVRGKPHGMIGDHQLAALDRALRQYPDRHALITLHHQAVPVGCAWLDQHNLKNA
DDLFAVLARHPQQKTILFGHVHQEFDEVHRGVRLIASPSTCIQFKPLCDGFALDESGPGW
RYLTLYPDGRVASEVWRLPVGQFVPDPDATGY
>G9YB01|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Hafnia alvei ATCC 51873|TrEMBL
MESLFQLTVARGAPVRILQITDTHLFAGEHETLLGVNTHRSYHAVLEAIHAEARPYDIVV
ATGDLAQDHSVAAYQHFANGIATLNKTCLWLPGNHDFQPAMVDTLANAGVNPAKHMLLGD
HWQIILLDSQVFGVPHGELSDYQLEWLERTLSLYPQRHALILLHHHPLPSGCTWLDQHSL
RNAHMLGEVLQHYPLAKTLLCGHIHQDLDLQWEGRRLLATPSTCIQFKPLCTNFTIDTLS
PGWRYLDLHPDGTLTTELHRLDGTEFRPDLDSDGY
>A0A844MK72|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Scytonema sp. UIC 10036|TrEMBL
MNPVFPLSIAQVSDMHLFADENEQLLGIPTNLSFQAVIGRLKQLRSELDLLLLTGDLSGD
GSPESYEMVQNLLRPLEICTHWLPGNHDSAIAMEQVLNLRLVSRRKSFERGGWNFILLDS
TVPGCVHGDLSAKTLHWLDFQLSMGGHKPTLLALHHPPFKVDSKWLDTSTLQNSQDLFAI
IDRHPQVKLVLFGHIHQEFHCQRHSVDYFGTPSTCIQFAPLSSKFSLDEKSPGFRLLKLY
PNGTWESSVERVPFSYKLDLAATGY
>A0A6P8J7P6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila mauritiana|TrEMBL
MRNCLPKFSKVFRRKSSAKSSSSSAGRENPSNEPDSDTEPYAVAIAAISDRSGDNRNERP
RPLPDDDSIRSRLISAAHLDLDLGLELDSNSTAVTTNGGLRPKSEGSCPEMKVETISAAT
SRPPPRPLHGTTGPVAISLPFVGRNSSKTPEEMELEYEANVEAESRDIMTPLRRNTRPLS
VSFGGGGGGGVGGGRSALQPEIVEAIRSLDVPALRLNNLSFAGSTDQKGERSSAEEEPLT
PDHDHEDSVVLRRKVICLERKAHSLYERRLPMVPKLHLLVAGKKNPPTEEEEFRTFQRNL
MDLKYPTVLPPNPPLKALLVFHKSDSICEAITAACQRHQLDVTLVKSKEEALDTLQKSYA
TAQCYHLIIIDARSSKNLDAEHIARTIRHTHGHHLTTIIAVCKKSFFEKDDVLIALLDAG
VNRCVAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRLKEVVLITDDLLRIQY
ANRATERLLNMRLDEIISKQLEDIFVSDLSTISEQCKNIKEFDGILTVRRKSQEGIPMHV
RVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHSVRRCSFDVRSIASDG
LRRTSLAKLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEI
RTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTAAIVPAKMKSNPIIMELLDE
SLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNT
YHNSTHAADVMQATGAFITQLTNKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSN
DALAVLYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTR
HFEHLAKFVSVFGGEEPRDHNPQTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIA
EEYFMQTDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDMPQLITY
MQINYSQWKKYDEQGVNTLAEIMAKQPPVGKMANSK
>A0A0L0C916|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Lucilia cuprina|TrEMBL
MRNCFTKITNVFRKKPIQQNQPENSRLNGEEFLQSPLHYEGAGKGEYKTTTLKTANTTTT
AACIIVNECSDTNDFDKRPGNNSSNDYYHDGDGDNNDNGDKRKNVIEHRKISGIVATDKQ
KAVKTTSQKTPSLGRNATANNHNDDKPLIFPQNSQKNLKNNIDTDFTNPLEQTNLQDLHP
TTIKNNDAETNKLLQQIKTTTTHTKLTSATNDHQRIESNTQITETAREHNNNTSHTSEEH
KTHTYIHEYKSFVEDNRRSFINSPLPLSLPRDIELFASEEILKRPTTAASHSNNNNNNNK
HSIEKDLKLKLPKVLSRPPSPSSIAEAANSSIVVNNKVVEAKTPEEIEYDAKVAAECEDV
MTPLPTDTQTKHLHPLAYGRNVQPVIVEVIRNLDANTLRINNLTLDDKVELLQRYECKHQ
HRRHNRGNNHNRLMPTEVNIQSVKQRQQLQQPNDDVSSDSDIADVVLRRKCQNTNRNDHS
KSGLYERRQPKGPKLKLILENNITTEIIPNKLSKKSDHEIERNVFEIKYPTVLPPNPNLK
ALLIFPKSDNICEVMQQACNRQHLEVTLVKSKESAMESLCSATECYHIIIVDARSAKHLD
AEHIARSIRHMSGHHFTTIIAVVKKSISERDDVLNALLDAGVNRCMAESTNLSMCTMELK
QTLHSIVRPHNVISTQQTLYTALHRLKEVLIITDDLLRIQYANRSAERLLNMRLDEIINK
PLAEIFVSDVSSINHNTGKGIREFDGILTVKRKNQDGIPMHVRVVPVACIGRTPTHFVFN
FDVPGGQTDFIATLPQPKEAPRGSLHSIRRGSFDVRSIASDGLRRTSLAKLTSLPLEAPI
TKIINLLSQVQENCSADEARLIDKVLEFLKREGLYSPQMKEIRPDDPIATDLIGALLTGP
NVYSSRRSSNDSIVKSGRTCNSTNTPGIMPAKMKATPLIMEILEESLNWEFNIFKLEEVT
ERHPLLYLGMEIFRRFDVFCTLGVDETVCKNWLALMESQYHADNSYHNSTHAADVMQATG
VFISQLAAKDLVMDRLEEATALIAAVAHDVDHPGRSSAFLCNSNSPLAIMYNDLTVLESH
HASTTFRLALADDNVNIFKNLDKDTYKLARSTIIDMILATEMTRHFEHLAKFVSVFGAEV
EPRDIVQTEEESSILMRRMLIKVADVSNPARPMICCIEWARRIAEEYFTQTDEEKAKDLP
IVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWDSFIDMPELITYMQINYSQWKKFEEQGI
HTLAEVKAKQMSLMNKKSALK
>A0A7U5ZEZ4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Enterobacter cloacae complex sp|TrEMBL
MESLLNLTVAGGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIV
ATGDLAQDQSSAAYQHFAEGIASFSVPCVWLPGNHDFQPAMYSSLQDAGISPAKCVFAGE
QWQILLLDSQVFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSL
RNSAALDRVLAKFPRVKNLLCGHIHQEQDLDWNGRRMLATPSTCVQFKPHCANFTLDTIA
PGWRWLELHADGSLTTEVCRLTGAKFRPDTASEGY
>A0A6P4EFS5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Drosophila rhopaloa|TrEMBL
MIISSQPNLVGSVTTTSTTTTTSAHMSEESVPSTCNCGAVGVSVGVGVGGALGARQSPPA
VEPTTTATPKTPTSTAPGRDSLTRPASESELNVGTGTSGTSSSGGGNSRPGHRKSSLALA
LTPEDEPMDVYQRNLMDLKYPTVLPPNPPLKALLVFHKSDSICEAITAACQRHQLDVTLV
KSKEEALDTLQKSYATAQCYHLIIIDARSTKNLDAEHIARTIRHTHGHHLTTIIAVCKKS
FFEKDDVLIALLDAGVNRCVAETTNLAMCSVELKQILHSIIRPHNVMSTQQALYTALHRL
KEVVLITDDLLRIQYANRATERLLNMRLDEIISKQLEDIFVSDLSTISEQCKNIKEFDGI
LTVRRKSQEGIPMHVRVVPVACIGSAPTHLIFNFDVPGGQMDFIATLPQPKEAPRGSLHS
VRRCSFDVRSIASDGLRRTSLAKLTSLPLEAPITKENCSADEARLIDKVLEFLKREGLYS
PQMKEIRTDDPIATDLIGALLTGPSVYSSRRSSNDSIIRTGSSTRTATIVPAKMKSNPII
MELLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAH
YRKSNTYHNSTHAADVMQATGAFITQLTNKDMLVMDRMEEATALIAAAAHDVDHPGRSSA
FLCNSNDALAVLYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMIL
ATEMTRHFEHLAKFVSVFGGEEPREHNCQTDEETSILMRRMLIKVADVSNPARPMQFCIE
WARRIAEEYFMQTDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDM
PQLITYMQINYSQWKKYDEQGVNTLAEIMAKQPPVGKMANSK
>A0A8I5ZX49|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Rattus norvegicus|TrEMBL
MTAKNSSKELPASESEVCIKTFKEQMRLELELPKLPGNRPTSPKISPRSSPRNSPCFFRK
LLVNKSIRQRRRFTVAHTCFDVENGPSPGRSPLDPQASSSSGLVLHAAFPGHSQRRESFL
YRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGAPNK
RSPAASQAPVTRVSLQVCGHGRLIKCRESKRC
>A0A1S3QLE5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmo salar|TrEMBL
MKKSRSVQRLSLAGEEEDNDTDSSGCAGKAESGLYSSSYTSGATLGAELRMGRSRRLASS
LQVPCWLRPRDRTRSPEILSNMPRPTSLPLCIPPRIAITPADADSELENGVSPGHTPLGS
QSPSLTLHPSFPQGGRRESFLYRSDSDYDMSPKNSVSRNSIASEGHAGEDFIVTPFAQVL
ASLRSVRSNFTLLANVSMPTVKRSPLGGVAPHNPRAALSDQQYEQLATDTLEELDWCLDQ
LETIQTHRSVSDMASNK
>G5QPV8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Salmonella enterica subsp. enterica serovar Rubislaw str. A4-653|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTIA
PGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A427ECE3|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas xanthomarina|TrEMBL
MPGASLTVEDSVLLVQLTDSHLFAEADGKLLGMNTCDSLEQVVELAIDEQPRIDLILATG
DLSQDGSVASYQRFRRLAERIEAPARWCPGNHDELAAMREACRGSALMEPVLEIGGWRVV
MLDTLVAGSVFGVLRNDQLELLERALSEAPDHHHLICLHHHPVSIGSRWMDTIGLRNPEA
LFEVLDRHSNVRALLWGHIHQEFDSWRNDVRLLASPSTGVQFAPQSEDFQVDNVAPGYRW
LRLYADGQLETGVSRVSGIEFEIDYSVKGY
>A0A399EUR4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Meiothermus luteus|TrEMBL
MLSRRRLLTLLGLGAVGVAAFWARAAAYRFEISRYRRVLLGLERPLRVVQMSDLHYGALV
HAGSVRAWVAAANAQSPDLVVITGDLVDSGVRLPGLGVLYRAATPDLEALLEALGQLRAP
LGVYAVWGNHDNSLPEVKRRLAKALPRYGVEPLSNRGVWVREDLYLSGVEDYWAEEADPR
AALAGYRPGRASLALAHNPDYWDFYYGLPVSLVLSGHTHGGQVYLPGLGAPWTPSYYGQS
YLGGFYSPGYSPASPPVHGFVSRGLGVTLLPLRVNAPAELVVFDFVPG
>A0A2P4SDV2|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Bambusicola thoracicus|TrEMBL
FDVENGPSPGRSPLDPQASSSSGLVLHTTFPGHSQRRESFLYRSDSDYDLSPKTMSRNSS
LPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGTANK
>A0A645GRI0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MTIVGADSSQPDLDEGHLGRENYGWIKEAFSGEKFKVFALHHHLVPIPLAGRENTVLVDA
GDVLDLLNKCRVNLVLCGHCHIPHVWNLNNMLVVNAGTFCSSKTRGKTTQCFNLIQAESS
KENGKRKAEKIENSGWKVRISRVFPQGNIELVTETVM
>A0A644XQ16|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MALFAISDLHFGTGINKTMDVFGYKWVNHVEKTIENWKDTVTTDDTVIIPGDISWGNNLD
EAKSDLDLIDSLPGRKIMLMGNHDYWWQSLSKVCAAYPNILFLQNNYYMYEDMAICGTRG
WVCPNSVKFTKEDEKVYNREQLRLKLSLDAAIKSGHGEKIMVVFHYPPVNENHDRSGFIN
ILEQYSEVKKVIYGHIHGISSDSEIFEGLHNGIDYSLVSSDFLNFKPITIEI
>A0A644VVZ5|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MTCNGIPENHFTFYPSRPIIKIPYRKARMAVRFAHLTDIHLGHRFAEKFGVDSKKNLITV
LQDIRLRGITHLAVTGDIAEDEEAPWFFKTIKEYGFQTYITLGNHDNPQAMELHYEHVHA
GRYYYKAPSEQACLLFCDSREAYLDEEQLCWLVKEIEASTLPILVFLHHPVLDCDNSFMD
RKYALKNRETVRSALQATHKNIHLFCGHYHTTDERSDGNIHQYITPSIFYQIQKYSETLQ
KDDKPFGYRIINLDKQISSQIITFGV
>A0A644ZXV6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MKIGVMSDLHIDSNAKKLAPGQTYDYLLAELLYNQEIDLLLLAGDVSSDYHDTFAFLDRM
RDHNVSKIQFVPGNHDFWSIRNHEENTDRIYQLFKQRDENPVGNPFLIGDEWAVVGNPGW
YDYGFASDSYTIEEFSRKKLKVGGWNDRRYVHWEKDDRTVAAEMLAELENDLKRVSNRKI
IMQTHVVTHPQFVIPLPHKVYDYYNAFLGSKSYMQVYDRYPIAYSVMGHVHFRKMFHEND
TTFYCACLGSSRHWYTEDPYIEMAYTMEEIVVDL
>A0A644VVM0|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|bioreactor metagenome|TrEMBL
MRLLGILITVTLAAHYSYIYFRLRNAIGPGWKWTALYLGLTLFLVFGSRALWQVDLGDYP
EFRKVLSYSVYMGLAFFFILFTAFVALDLARLLAWLADTLFSTDLRRLLPSPKSRTLGAV
GLALLVCAYGWFEALNVHPRHVTIETERLPAGTDRIRIAHITDVHLGWIIQEERLDRILA
PVRAAKPDLVVSTGDLVDDNMEFRDEEIALLRGLTPPLGTYAVTGNHEYHVGVRQAVEFK
ERAGMKVLRNEHHSVGGLVLVGMDDPSARYYGEGIPPEGDILASLPDDRFVVLLKHQPRV
EPESVGLFDLQLSGHTHGGQIWPFYWLTRMVYEYRPGLRALAPSPRGGEAYADENSRESS
IYVSNGAGTWGPPLRFFAPPEVTIFDIVRKKGN
>A0A6C0TV54|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Pseudomonas sp. OIL-1|TrEMBL
MPPVITTEAGYVSIVQLTDSHLFADHSARLLGLDTFASLNAVIDQVLDEVDQMDLVLATG
DITQDGSEGGYQRFMDAVKRLPAECRWLPGNHDDAQLMRTLGDESGFNAEWVDLSSWRIV
LLDSSIPGAVPGHLDEQQLDRLDRALATAGGRHLLVSLHHHPVDIQSDWMNPLGLQNADR
LLQCIDDSGSVRALLWGHIHQHLDLMRGNVRLLATPSTCIQFDAHSADFATDTQSPGYRW
LRLYDDGSIETQVSRLPDGLFVADPGASGY
>A0A7R9N986|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Candidatus Methanoperedenaceae archaeon GB37|TrEMBL
MKILHLADVHIDEKKTVNGKIIYDEEGINIRLKDLLDCISQVKNTAEKENVSLTLIAGDL
FERKTPTPFETYTATKVLSELGSICPVVLTPGNHDAVDSVKALGFIKNIYVPEPFTPIRF
SDITIFCVPYPDLKEGSRSEVKQLYERKILETSKKLKENSNFLVALCHAPVEGASYPTTD
RDVNEVTLSPSCFKHLDYAALGHIHKPQRIENIYYPGSVDTWRRQEADEEKGFYIIDTDT
HEVTFTPLPPDLCIT
>B1PSD9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus musculus|TrEMBL
MSLPTSCEHLGLGKVARFRSAYVHGSPYAINKPIDIKPQRRRFDVDNGTSAGRSPLDPMT
SPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVL
ASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQ
LETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPT
QKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFR
IAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADV
VQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSV
LENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVE
TKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRER
ERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQS
TIPQSPSPAPDDQEEGRQGQTEKFQFELTLEEDCESDTEKDSGSQVEEDTSCSDSKTLCT
QDSESTEIPLDEQVEEEAVAEEESQPETCVPDDCCPDT
>D0ERY7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Magnaporthe oryzae|TrEMBL
MENAACNLIYVDRSIRQDRIVRASSYNSDGTEGPLAGSSDYETQALRENVQLLLEFIGDV
HLVATGASCLTQLFDLLDHSIIETKPIIVLIDVSNNEPTPKDRPRSGSHSRPRTPSRTTE
SLDDEFSHTSNDADLYGTRLLQRIVSESHLRNVSSLVVPISLVGSPGVDEFSADVTQASI
REKSGRISKNPHDSVDLGLFKYCLDLGATDVMVKPLKCVTSIQVHAYQAYKEASKQRQAV
LELKRGRKRSWVGVDDAKPYAYLREDMVSSLMGRICRPGDDQDDRVSNVRISVSQDRRSQ
IAKAVSRWHFCAHDFSDDELIVAATLMLKHALAMPELERWRMSTDQLSTFLIACRAAYNN
FVPYHNFRHVIDVLQATFNFLVQIGSLPPFPPRSDDYIATPQPTSPIATLMKPFEALTLL
VTAVGHDVGHPGVNNGFLVTLNAPLAQLYNDRSVLESFHCAAYSQILRRYWPAAFEDLQM
RNLMISSILATDMGLHFDYMKKLGDLQEKLHENNAIEGWNGRVIEEHKALACAILIKCAD
ISNVARKHDTALKWTHILSDEFSRQASMETDLGIQSSLMAPPKKDVISLSKAQLGFMNLF
AIPLFQGVADILPAMQYCVDELEINKALFDQMIVAEQSRHDRPKAAREPTLSPKTMSVII
PAESEYAIDISDGHGKNDISAEDVLKRHANPEEKPDTNPEHKPPHIPEPYNQYKEVNGTT
SEFEAVADFAATDPFNMQESRPCTSRKQRCSEATDGSASAPGTGDWASQATSATTGKMPL
SPSTQGTSILSQESLDRPVSVPATMVTAPDEPHANKHQLPVRLDHKSHSDSRLEISPSHS
VEDDTHSTSPNGKLSVEGSTLKKKSSRFRMNAFTFFRRHRGASPPLSAADTAG
>D0ERY8|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Magnaporthe oryzae|TrEMBL
MGEGSAEGEATVPSAAIQVVVLGSGGGPEESNTTAFLVRSTSTGWGKGSIVALDAGVHLS
AIKRILEDTQPPGLASGELPLPHILQEGPFKGLELPFATPSANSSYIQRTLVDTYLITHP
HLDHIAGFVINTAGLKGSRPKRLAGLPNTIEAFKNHIFNNIIWPNLTDENNGAGLVTYNR
LVEGGSPAIGEGDGRGYLEISDGLAVKVWGVSHGHCMEKHSHRGSASSSTRFGSMDCASP
SMNAMGMGGSIPPGMMSPRTLAHHNSAGPSLSLFLQQQAVARGDMTAGMQTPHAGLGTRG
SSISAMFGGHQQLMDTPCVYDSSAYFLRDLATGREVLIFGDVEPDSVSFTPRNAIVWAEA
APKIATGRLSAIFIECSYDDSQESDRLYGHMTPKYIREELAILAAEVAHVRANMARDGRK
RKRDGEDSILPNSGVATPGGLRRRVTANNSSMGLLEDPVSPRTVRPPRAPSADDLSQAAI
QRGQQQSAYRDPIDSPRIATPTAELSLREIEAGSENASTSRKPSTAETPSLPLKGLKVVL
IHVKDRMDDDTPAGDIIMQELAEHEAEAPTGCEFILSRAGEALYL
>Q309F4|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trypanosoma cruzi|TrEMBL
MLTELHGCSSLFVTTTDRCSIMAKMNEEAECFCVSVVMPSGVCYQDEFDEEGLCNVKETL
GEHVSWARFFSVVREAFNNGQVTVQKATDASVEVMCHADASGEGAGVCGAEFNVSKVDVS
VLPTIEKGLVDLYQFQAHPNTQEQKLKKLTEEVAQLKIKTDQLEKEACFLKEIAHRRRKL
DIYNIQRIKQLREEVTNYEGIYECAHRATKGEATTNMSHRSSTQARHKGRIRQPLGEKEC
AAYDPELLCLIKSRWMTLSGIDAGPSCNRVIVPSPSPGVSNQTPVFGNKQQEVVWEAMNK
LDAWDYNVFEIQQTMSGDDFASLHHQPNGGSLFITMYALLIKYSFLSKFNIDEQIALNWI
SCVESGYNGNPYHNSMHAADVLHITHYILSEGGMIERCQLSDLQVFAALFAAAIHDYNHP
GVNNNFHIKTQTYGAIVYNDRSVLENAHVSSVFELMKNPRFNILESFSEDQQKEIRETVI
EMVLATDMSLHGKHIAHFNERLEEHASFTERENQNLALVMALKMADISNCGRPLEIYLKW
SSKLSDEFYLQGDRERNLGMQCSPFMDRMEPALAKGQILFINYIIIPFFEKMAVFLPKMR
LAVECAESCKAYWLKSGQG
>Q38F42|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trypanosoma brucei brucei (strain 927/4 GUTat10.1)|TrEMBL
MTHNGGRHLLEAVTLCGSILTRYKRSNMKLDEAEVRALKELFEKYQDILVDGSPGLPTHA
SGPMIQPPVTNMVAPYDSPTDTIVKFVEGTINLQRPIVEVLHVMNEHLSLVLRAKNTHVF
YVDPVNNLLYDPIHGVAAALDESSPIGKAIVSGERLNVAGTLYIPIISEGMPLGCVLSPC
GRADYHASTMLESSLRVISTSLKNIIQAEKLNWNKEKAEAMLRMATQLARDNLEETVLAS
SIMNTVKSLTESARCSLFLVRGDVLEAHFEDGNVVTIPRGAGIAGYVAQTGETVNIVDAY
ADDRFNREVDKATGYRTKTILCMPVMYEGTIVAVAQLINKLDLTTESGLRLPRVFGRRDE
ELFQTFSMFAGASLRNCRINDRLLKEKKKSDVILDVVTVLSNTDIRDVDGIVRHALHGAK
KLLNADRSTLFLVDKERNELCSRMADSVAGKEIRFPCGQGIAGTVAASGVGENIQDAYQD
PRFNREVDKQLGYRTQAILCEPIILNGEILAVVQLVNKLDSSGEVTVFTEDDRDTFRVFS
LFAGISINNSHLLEFAVKAGREVMELNEHRATLFNKNVPSRGVKRVTAITNREREAVLRI
EFPNVDVTDIDFDLFQARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCR
KKYRNVPYHNFYHVVDVCQTIYTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSF
YLKTESPLGILSSASGNKSVLEVHHCNLAVEILSDPESDVFGGLEGAERTLAFRSMIDCV
LATDMARHSEFLEKYLELMKTSYNVDDSDHRQMTMDVLMKAGDISNVTKPFDISRQWAMA
VTEEFYRQGDMEKERGVEVLPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQW
TVDRTKSNRAQWERVLEARSTGASS
>Q38F46|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trypanosoma brucei brucei (strain 927/4 GUTat10.1)|TrEMBL
MFMNKPFGSKRCEPFHESEHLCEAFAITEAILARYQRGKRSFTSSEKSGLAALIKRIPYD
ILVEVLDQSGFTPTSNATPPVDYLAMMEHTMTHGASITHALQYLNDLMTKCTGCPGIRTY
YHNPNDDVLADPVHDTAALIDETTAVGKSVVTKQYLNIAGAHYIPLIHGDIVVGCVEVPR
FSGNLEELPSFPSLIRAVTCTAHKFIEEARINWNREKAEAMLQMATRLARDNLDETVLAS
SIMNTVKSLTESARCSLFLVKDDKLEAHFEDGNVVSIPKGTGIVGYVAQTGETVNIVDAY
ADDRFNREVDKATGYRTKTILCMPVMYEGTIVAVTQLINKLDLTTESGLRLPRVFGKRDE
ELFQTFSMFAGASLRNCRINDRLLKEKKKSDVILDVVTVLSNTDIRDVDGIVRHALHGAK
KLLNADRSTLFLVDKERNELCSRMADSVAGKEIRFPCGQGIAGTVAASGVGENIQDAYQD
PRFNREVDKQLGYRTQTILCEPIILNGEILAVVQLVNKLDTSGEVTVFTEDDRETFRVFS
LFAGISINNSHLLEFAVKAGREVMELNEHRATLFNKNVPSRAVKRVTAITKVEREAVLVC
ELPSFDVTDVEFDLFRARDTTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCR
KKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSF
YLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFGGLEGAERTLAFRSMIDCV
LATDMAKHGSALEAFLASAADQSSDEAAFHRMTMEILLKAGDISNVTKPFDISRQWAMAV
TEEFYRQGDMEKERGVEVLPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWT
VDRIKSNRAQWERVLETRLSTSSGNNSSTR
>Q49UB9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trypanosoma cruzi|TrEMBL
MFTQQRLRPNTQELLKETNHLCEAFAISESILARYQRNNRQLSESEKKAFASLLLRVPHD
FLTETVASLGTSKTSSIGPTTDLGSLIDNVFGFGKPLKDVFQLLNQELGNCLNSPRCRVY
YLDPTDNLLKDPVYATASTLDETTPLGKAVLTGIQREIAGTLYLPLSFEGKVIACVESAW
GSPEKGDKRRIKETLQFVACAMHNAIESERLRWNKEKAEAMLEMATQLARDNLDEAVLAN
SIMNTAKVLTESDRCSIFLVKDDTLEAHFEDGNIVAIPIATGIAGYVAQTGQTVKISDAY
SDDRFNREVDKATGYRTKTILCMPVTYEGSIVAVAQLINKLDMVTESGLRLPRTFGKRDE
ELFQTFSMFAGASLRNCRINEKLINEKRKSDAILDVVTLLSNTDIRDVDGIVRHVLHGAK
RLLYADRSALFLVDKERNELYSRIADSVAGKEIRFPCGQGIAGIVASTGIGENILDAYQD
PRFNREVDKQLGYRTQALLCEPIVLNGEILAVVQLVNKLNEAGEVTVFTESDRETFRVFS
LFAGISINNSHLLEFAVKAGREMMELNENRALAGGRTGSLRNIKRPLAITEAERQAVRDI
NLAHLDITSIDFDLFYLRENMELPLDAAAAVAYRLIVGTGLPQKFRCRDDTLLNFILQCR
KKYRNVPYHNFYHVVDVCQTVYTFLYKGAVCEKLTELDCFVLLVTALVHDLDHMGLNNSF
YLKTDSPLGILSSASGNASVLEVHHCNLAVEILSDPDSDVFEGLDAADRTLAYRSMIDCV
LATDMAKHGKSLESFLSVLGNPETSEQRIAELTMQIVLKAGDVSNVTKPFDISRLWAMAV
TEEFYRQGDMEKEKGVEVLPMFDRSKNTELAKGQIGFIDFVAGPFFKKIVSASLTGMQWT
VERVESNRLEWQRSLDAK
>Q4ZHU6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trypanosoma cruzi|TrEMBL
MSEDAGLPVPRSQWVERSVSCATCGKRFSLFTAKSNCPCCGKLCCSDCVQAECAIVGGSA
PSKVCIDCFSMLQSRRRVEPDEGSSFREFNAASAFPLQTRLLADGRVESGETSRVSPPND
GRVQHFSRANGYSNSLPVLDEYVDDLLRKSELLRMENDVLLNRLREQEAEIQALRLERDR
AVARIVPDGGSMAGRSGTPQVSDEIVKELREELAVAHLRIESVEGELKNALDRAKSSETV
VKNLKQHLCNYKEEVVRLLQSREEVEMLPGVSGHRDMISTRRLPPSIVQDTILAVVPPKS
CAAIGTDVDLRDWGFDTFEVASRVPSVLQSVAMHVALAWDFFASQEEAQKWAFLVAAVEN
NYRPNPYHNAIHAADVLQGTFSLVSAAKPLMEHLTPLECKAAAFAALTHDVCHPGRTNAF
LAAVQDPVSFKFSGKGTLEQLHTVTAFELLNVTEFDFTSSMDNASFLEFKNIVSHLIGHT
DMSLHSETIAKHGAKLSAGGFDCTCKEDRLEALSLLLHAADIGASSRGVAIARKWLVILQ
EFADQAEDERRRGLPVTPGFDTPSSVEKSQIPFLDFFVIPTFDLLHQLFPSIEEPLHNLR
KLRELYAAKAGVTTPFPPPVDYRSREERIRSLEAELAYFRRREEEFHRQLQELRTASENE
NKSSAAPMTREGALNKQSQLVCRGEGNMNADWADAGGGFRNGKDVRDLQDVSMDHLVSSK
TVESDTGDSRPRSRRGSKAETTKAYERNLGEREAALMATARLMENREKRLAVLSEKLAEI
AEGLHEERKRLKPMEEFKTPCFSRETELISEESASMDVTHRFSTQWEAEGRLARKYRELD
ELLLIVRAMRMGYAARRNTHLGWKALSATLAEREAAITEAVELSRQRRRHLEEGRGLHPT
ATQLDRLENAIFQLMSATTLLTQC
>Q6S996|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Leishmania major|TrEMBL
MHSAVFSPDAPYCGAAGSNHLCEAVALCQSILARYRRTGTSFSSTELKAIQALRTEFPDT
AQEPAANSAASPDQTTKDFLSILDDATDVPHNPQNDIVAFVEECCDNTKEPTVLFAAINE
RISAVTCSRNVRTYMVIANDNLLWDPVNGVAALIDDVTPLGKCAQARNMLTIANTLYIPL
WFRSELVGCVEVPGACIPRDKATCAQLLLRCVTVAVRNSINISIRKREANKIEAMVGMAT
RLARDTLEESVLVQSIINTAKTLTESDRCSIFLVKADGSLEAHFEDGNVVVLPAGTGIAG
HVAESGAVVNIPNAYEDDRFHRSVDKVTGYHTRTILCLPIAFEGTIVAVAQLINKLDMVT
QSGQRLPRVFGRRDEELFETFSMFAAASLRNCRINETLLKEKKKSDAILDVVALLSNTDI
RDVDSIVRHVLHGAKKLLNADRSSMFLLDKERNELYSKMADSANEIRFPCGQGIAGTVAE
SGVGENIMDAYADSRFNSAVDRQLGYRTQSILCEPITLNGEVLAVVQLVNKLGDDGSVTC
FTPMDRETFQVFSLFAGISINNSHLLEFAVNAGREAMTLSLQRNSITAQRAPKSVKVIAV
TPEEREAVMSIDFGGAYDFTSPGFNLFEVREKYSEPMDAAAGVVYNLLWNSGLPEKFGCR
EQTLLNFILQCRRRYRRVPYHNFYHVVDVCQTLHTYLYTGKASELLTELECYVLLVTALV
HDLDHMGVNNSFYLKTDSPLGILSSASGNNSVLEVHHCSLAIEILSDPAADVFEGLSGQD
VAYAYRALIDCVLATDMAKHADALSRFTELATSGFEKDNDTHRRLVMETLIKAGDVSNVT
KPFETSRMWAMAVTEEFYRQGDMEKEKGVEVLPMFDRSKNNELARGQIGFIDFVAGKFFR
DIVGNLFHGMQWCVDTVNSNRAKWQEILDGRRDSIRSSIV
>Q6S997|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Leishmania major|TrEMBL
MAYFTAKRASSMGASTVPSGNDHLLEALTLCDCILSRYKRCGVQLNDAEAAAFANLQQRI
SSISGHAADAACPAGATRKQSQELGLHEYAQLAQRCLIFQNPLAQIVATINEEFSKLVSC
SVRTHYANTNDAVLCDPVHDTVATIDTSTPIGRCAKTKTTVTISDTVYIPLCYNSHVVGC
LEVESTAIDTSTPFFGYLLQVAALTLQNATSIDTLRWETRKAEAMVGMATRLARDTLEES
VLVQSIINTAKTLTESDRCSIFLVKADGSLEAHFEDGNVVVLPAGTGIAGHVAESGAVVN
IPNAYEDDRFHRSVDKVTGYHTRTILCLPIAFEGTIVAVAQLINKLDMVTQSGQRLPRVF
GRRDEELFETFSMFAAASLRNCRINETLLKEKKKSDAILDVVALLSNTDIRDVDSIVRHV
LHGAKKLLNADRSSMFLLDKERNELYSKMADSANEIRFPCGQGIAGTVAESGVGENIMDA
YADSRFNSAVDRQLGYRTQSILCEPITLNGEVLAVVQLVNKLGDDGSVTCFTPTDQETFK
VFSLFAGISINNSHLLEFAVNAGREAMTLNLQRNSITAQRAPKSVKVIAVTPEEREAVMS
IDFGGAYDFTSPGFNLFEVREKYSEPMDAAAGVVYNLLWNSGLPEKFGCREQTLLNFILQ
CRRRYRRVPYHNFYHVVDVCQTLHTYLYTGKASELLTELECYVLLVTALVHDLDHMGVNN
SFYLKTDSPLGILSSASGNNSVLEVHHCSLAIEILSDPAADVFEGLSGQDVAYAYRALID
CVLATDMARHGDLSRVFDDMAKAGYDSNDQESRRLVMETLIKAGDVSNVTKPFETSRMWA
MAVTEEFYRQGDMEKEKGVEVLPMFDRSKNNELARGQIGFIDFVAGKFFRDIVGNLFHGM
QWCVDTVNSNRAKWQEILDGRRDSIRPSIV
>Q6XG56|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trypanosoma cruzi|TrEMBL
MAETGGRHLLEALTLCEVILSRYKRCGLQVDEAETKAFQAVSERFHEITHATQGGNAAFV
KPLNIIKMAPAIPTIGAVFQTPLESVTKLMEKCIDLCLPIKEVFIMLNEQISAVLRTKNT
RTYYLDSGDDLLKDPVNGIAALVDERTPLGKTLFSTRPFSIAGTLYIPLLHNETVIGCVE
NPSGRTDYHSQAIIEAVLRVAATVIHNAIESERLRWNKEKAEAMLEMATQLARDNLDEAV
LANSIMNTAKVLTESDRCSIFLVKDDTLEAHFEDGNIVAIPIATGIAGYVAQTGQTVKIS
DAYSDDRFNREVDKATGYRTKTILCMPVTYEGSIVAVAQLINKLDMVTESGLRLPRTFGK
RDEELFQTFSMFAGASLRNCRINEKLINEKRKSDAILDVVTLLSNTDIRDVDGIVRHVLH
GAKRLLYADRSALFLVDKERNELYSRIADSVAGKEIRFPCGQGIAGVVASNGIGENILDA
YQDPRFNREVDKQLGYRTQALLCEPIVLNGEILAVVQLVNKLNEAGEVTVFTESDRETFR
VFSLFAGISINNSHLLEFAVKAGREMMELNENRALAGGRTGSLRNIKRPLAITEAERQAV
RDINLAHLDITSIDFDLFYLRENMELPLDAAAAVAYRLIVGTGLPQKLRCRDDTLLNFIL
QCRKKYRNVPYHNFYHVVDVCQTIYTFLYKGAVCEKLTELDCFVLLVTALVHDLDHMGLN
NSFYLKTDSPLGILSSASGNASVLEVHHCNLAVEILSDPDSDVFEGLDAADRTLAYRSMI
DCVLATDMAKHNELLNLFLAAMEKPYQIGDVASRQMMMDVIVKAGDVSNVTKPFDISRLW
AMAVTEEFYRQGDMEKEKGVEVLPMFDRSKNTELAKGQIGFIDFVAGPFFKKIVSASLTG
MQWTVERVESNRLEWQRTLDVKAAGDGNK
>Q8WQX9|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trypanosoma brucei|TrEMBL
MFMNKPFGSKRCEPFHESEHLCEAFAITEAILARYQRGKRSFTSSEKSGLAALIKRIPYD
ILVEVLDQSGFTPTSNATPPVDYLAMMEHTMTHGASITHALQYLNDLMTKCTGCPGIRTY
YHNPNDDVLADPVHDTAALIDETTAVGKSVVTKQYLNIAGAHYIPLIHGDIVVGCVEVPR
FSGNLEKLPSFPSLIRAVTCTAHKFIEEARINWNREKAEAMLQMATRLARDNLDETVLAS
SIMNTVKSLTESARCSLFLVKDDKLEAHFEDGNVVSIPKGTGIVGYVAQTGETVNIVDAY
ADDRFNREVDKATGYRTKTILCMPVMYEGTIVAVTQLINKLDLTTESGLRLPRVFGKRDE
ELFQTFSMFAGASLRNCRINDRLLKEKKKSDVILDVVTVLSNTDIRDVDGIVRHALHGAK
KLLNADRSTLFLVDKERNELCSRMADSVAGKEIRFPCGQGIAGTVAASGVGENIQDAYQD
PRFNREVDKQLGYRTQTILCEPIILNGEILAVVQLVNKLDTSGEVTVFTEDDRDTFRVFS
LFAGISINNSHLLEFAVKAGREVMELNEHRATLFNKNVPSRAVKRVTAITKVEREAVLVC
ELPSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCR
KKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSF
YLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCV
LATDMAKHGSALEAFLASAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAV
TEEFYRQGDMEKERGVEVLPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWT
VDRIKSNRAQWERVLETRLSTSSGNNSSTR
>Q9GQU6|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Trypanosoma brucei|TrEMBL
MTHNGGRHLLEAVTLCGSILTRYKRSNMKLDEAEVRALKELFEKYQDILVDGSPGLPTHA
SGPMIQPPVTNMVAPYDSPTDTIVKFVEGTINLQRPIVEVLHVMNEHLSLVLRAKNTHVF
YVDPVNNLLYDPIHGVAAALDESSPIGKAIVSGERLNVAGTLYIPIISEGMPLGCVLSPC
GRADYHASTMLESSLRVISTSLKNIIQAEKLNWNKEKAEAMLRMATQLARDNLEETVLAS
SIMNTVKSLTESARCSLFLVRGDVLEAHFEDGNVVTIPRGAGIAGYVAQTGETVNIVDAY
ADDRFNREVDKATGYRTKTILCMPVMYEGTIVAVAQLINKLDLTTESGLRLPRVFGKRDE
ELFQTFSMFAGASLRNCRINDRLLKEKKKSDVILDVVTVLSNTDIRDVDGIVRHALHGAK
KLLNADRSTLFLVDKERNELCSRMADSVAGKEIRFPCGQGIAGTVAASGVGENIQDAYQD
PRFNREVDKQLGYRTQTILCEPIILNGEILAVVQLVNKLDTSGEVTVFTEDDRETFRVFS
LFAGISINNSHLLEFAVKAGREVMELNEHRATLFNKNVPSRAVKRVTAITKVEREAVLVC
ELPSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCR
KKYRNVPYHNFYHVVDVCQTIYTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSF
YLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFGGLEGAERTLAFRSMIDCV
LATDMAKHGSALEAFLASAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAV
TEEFYRQGDMEKERGVEVLPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWT
VDRIKSNRAQWERVLETRLSTSSGNNSSTR
>Q9QXI7|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Mus musculus|TrEMBL
MTAKNSPKEFTASESEVCIKTFKEQMRLELELPKLPGNRPTSPKISPRSSPRNSPCFFRK
LLVNKSIRQRRRFTVAHTCFDVENGPSPGRSPLDPQAGSSSGLVLHAAFPGHSQRRESFL
YDLDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFTLLTNLHGAPNK
RSPAASQAPVSRVSLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLN
RELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLM
HSSSLNNTSISRFGINTENEDHLAKELEDLNKWGLNIFNVAGYSHNRPLTCIMYAIFQER
DLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLE
ILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIF
QNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQV
LRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQ
VGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQSPSPPLDERSRDCQGLM
EKFQFELTLEEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLEETDIDIATEDKSPID
T
>O76074|3',5'-cyclic-AMP phosphodiesterase|EC 3.1.4.53|Homo sapiens|Swiss-Prot
MERAGPSFGQQRQQQQPQQQKQQQRDQDSVEAWLDDHWDFTFSYFVRKATREMVNAWFAE
RVHTIPVCKEGIRGHTESCSCPLQQSPRADNSAPGTPTRKISASEFDRPLRPIVVKDSEG
TVSFLSDSEKKEQMPLTPPRFDHDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLI
SADRYSLFLVCEDSSNDKFLISRLFDVAEGSTLEEVSNNCIRLEWNKGIVGHVAALGEPL
NIKDAYEDPRFNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDE
KDFAAYLAFCGIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIIS
FMQVQKCTIFIVDEDCSDSFSSVFHMECEELEKSSDTLTREHDANKINYMYAQYVKNTME
PLNIPDVSKDKRFPWTTENTGNVNQQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEENTGK
VKPFNRNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETREL
QSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWIL
SVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGV
NNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAI
LATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAE
LVATEFFDQGDRERKELNIEPTDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCF
PLLDGCRKNRQKWQALAEQQEKMLINGESGQAKRN