>P91119|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Caenorhabditis elegans|Swiss-Prot
MDDASVLKYLQENPKLVEDFVVSNEISPETFKRWAVRRTMKYKNVKNGTSGGTGAWTEPD
LSMKRRVILETSDNRTRILYEITQCCGQLIGTNSIELIVQNDEGAFSCRKTENGELKLKK
VKTSKSADYIQTIVNAGNQTIAEIHFYTQLDSTEKSIVNAVCTWAAATNYYSELYTHKQE
GSDGQDIHENIAKQRKLSNFLLDVARSIFHDIVSMDAVIIKVMNFAQKLVDADRASLFLV
DSKNAQIYARIFDVGTGDEEHVRVNSEGQKEIRFDMSKGIAGYVASTGEGLNIENAYEDE
RFNADVDSKTGYTTKTILCMPILIRGIVIGVVQMVNKHDGVFTRQDEDAFEIFAVYCGLA
LHHAKLYDKIRRSEQKYRVALEVLAYHSVCNADEVNKLKKIEINNRIVELETIDFNGMRL
SELEKPLYAVYMFKTLFADTLRFDTEDLIRFVLTVRKNYRRVAYHNWAHGWSVAHAMFAT
LMNSPDAFTKLEALALYVSCLCHDLDHRGKNNAYMKTMSTPLASIYSTSVMERHHFNQTV
TILQQDGHNILKSLSSEDYKKTLSLIKHCILATDLALFFSNKAKLNVILDNNTFDINRQE
HRLLTQAVMMTGCDLVASAKPWNIQTETVKVIFEEFYDQGDAERLSGKEPIPMMDRQQAH
MLPQMQVGFMRGICMPCYDLIARIFPKNDKMRERCEYNAKKWEELAEEQRKKQEALAQQN
GEANETQE
>Q9Y233|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Homo sapiens|Swiss-Prot
MRIEERKSQHLTGLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRKNNKSEDESAP
KEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNQLLLYELSSIIKIATKADGFALYFLGEC
NNSLCIFTPPGIKEGKPRLIPAGPITQGTTVSAYVAKSRKTLLVEDILGDERFPRGTGLE
SGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVC
RGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELY
SDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYT
GYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHR
IRHSECIYRVTMEKLSYHSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIF
VYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTD
LERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNI
FSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMM
TACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFY
NAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATWISSPSVAQKAAASED
>Q8CA95|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mus musculus|Swiss-Prot
MSNDSTEGTVGSCNATGLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRKTNKAKD
EPSPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNHLLLYELSSIIRIATKADGFALYF
LGECNNSLCVFIPPGMKEGQPRLIPAGPITQGTTISAYVAKSRKTLLVEDILGDERFPRG
TGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQ
VQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKN
KELYSDLFDIGEEKEGKPIFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREV
DLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCAN
MYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMRFNLPARICRDIELFHFDIGPFENMW
PGIFVYMIHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNNG
LFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLE
GHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLHNQSHRDRVI
GLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKRDEVPQGQ
LGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQWEKVIRGEETAMWISGPGPAPSKST
PEKLNVKVED
>Q9QYJ6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rattus norvegicus|Swiss-Prot
MEDGPSNNASCFRRLTECFLSPSLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRK
NNKAEDEPSPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNHLLLYELSSIIRIATKAD
GFALYFLGECNNSLCVFTPPGMKEGQPRLIPAGPITQGTTISAYVAKSRKTLLVEDILGD
ERFPRGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCLSHQEVATANLAWA
SVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALF
QVDHKNKELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADP
RFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCAL
ALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMHFNLPARICRDIELFHFDIG
PFENMWPGIFVYMIHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAI
LQNNNGLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTV
SILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLHNQS
HRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKRD
EVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQWEKVIRGEETAMWISGPAT
SKSTSEKPTRKVDD
>B7YZV4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Drosophila melanogaster|Swiss-Prot
MQPSSPNATNYLADNIQISSANLSQTEMVVGRDSADYTAMHSINVGVGNSFLRGDTDIPQ
ESGHSFETPSNMSFTAGQWDTESLPPVDTPDALNKAAGRIRSLLRRMDHETVAYEDMQRN
LHYAARVLEAVFIDESREGCNGNCKNLNCSRHSHGRDDQQQDNNNSNRSCSLQEASPGGA
GAGVTPGADNQDSIESRTKGVSQAPQTHSGPTGPPSNTSSETIAQPAPKLQPALETVRES
VMEESPSKDPGDKGPPPPASTSTLTSQTTTSSSATAEPSAKAAESQAGSAGSSGSCSNPA
AVHRQRRLRTPTWARSMSTNKTRLADEDDELSEVQPDAVPPEVREWLASTFTRQMATSRR
KSDEKPKFRSVAHAIRAGIFVDRMYRRVSSSALTAFPPDVVRLLKNLDDWTFDVFALTEA
ASGQVVKYVAYELFNRYGSIHKFKIAPGILEAFLHRVEEGYCRYRNPYHNNLHAVDVMQT
IHYCLCNTGLMNWLTDLEIFASLLAALLHDYEHTGTTNNFHVMSGSETALLYNDRAVLEN
HHASASFRLLREDEYNILSHLSREEFRELRGLVIEMVLGTDMTNHFQQMKAMRQLLTLQE
ATIDKQKVLSLVLHCCDISHPAKQWGVHHRWTMLLLEEFFRQGDLEKELGLPFSPLCDRN
NTLVAESQICFIDFIVEPSMGVMSDMLELILAPIAPMNKSKPATLVEHETTANSTTNSAI
VIPNSGITPSMDKPRDHRTEAKTTAAECLARKSVTGTTASKFNIPKPWLTCLVENKRIWK
EQAVKDAEARALATAAEEAAAAAAAEAEESKPETETADGEQSEPAAEPADGAAA
>P36599|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Schizosaccharomyces pombe (strain 972 / ATCC 24843)|Swiss-Prot
MHAALEIKEAEFQTDQVVGLVENSFTLYSLGQNGGPLESCCSSHLISDGAFQEIISLDGG
SHLSALVELIQSKHLSVDSWSSITKYDNYTVENESYAKAWHLSEQRIKTFLITHCHLDHI
YGAVINSAMFGPQNPRTIVGLNYVIDTLKKHVFNNLLWPSLDKAGFINFQVVEPSMYTSL
TTTLSILPFPVNHGSSFGQELKSSAFLFRNNLSDRYFLAFGDVEPDMVASEPLNIHIWRA
CSSLIAQRKLSHILIECSTPDIPDTLLFGHFCPRHLVNELCILQSLVQSYGVIMPTLTCL
LTHLKSHPLQSANPADVILEQLESLSSKSSLSVTFKILQRGQFYKF
>P22434|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)|Swiss-Prot
MVVFEITILGANGGPTEYGTQCFILKPARTEDPELIAVDGGAGMYQLREMLVQGRNENEG
DDELVPSFYEHDREPIEFFIDSKLNIQKGLSKSLLQSLKRQGEHFESANTMKKTYEVFQG
ITDYYITHPHLDHISGLVVNSPSIYEQENSKKKTIWGLPHTIDVLQKHVFNDLIWPDLTA
ERSRKLKLKCLNPKEVQKCTIFPWDVIPFKVHHGIGVKTGAPVYSTFYIFRDRKSKDCII
VCGDVEQDRRESEESLLEEFWSYVAENIPLVHLKGILVECSCPLSSKPEQLYGHLSPIYL
INELSNLNTLYNSSKGLSGLNVIVTHVKSTPAKRDPRLTILEELRFLAEERNLGDLRISI
ALEGHTLFL
>P14099|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bos taurus|Swiss-Prot
MRRQPAASRDLFAQEPVPPGSGDGALQDALLSLGSVIDVAGLQQAVKEALSAVLPKVETV
YTYLLDGESRLVCEEPPHELPQEGKVREAVISRKRLGCNGLGPSDLPGKPLARLVAPLAP
DTQVLVIPLVDKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVALKRVQALQQRESSV
APEATQNPPEEAAGDQKGGVAYTNQDRKILQLCGELYDLDASSLQLKVLQYLQQETQASR
CCLLLVSEDNLQLSCKVIGDKVLEEEISFPLTTGRLGQVVEDKKSIQLKDLTSEDMQQLQ
SMLGCEVQAMLCVPVISRATDQVVALACAFNKLGGDLFTDQDEHVIQHCFHYTSTVLTST
LAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNEL
VAKVFDGGVVEDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTR
NILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEA
QYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAIL
SMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNY
LEDMEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNT
HGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRTNKQHHSLLL
CLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQI
SFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEY
EVPDLDGARAPINGCCSLDAE
>O00408|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Homo sapiens|Swiss-Prot
MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDI
SGLQRAVKEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCN
GLGFSDLPGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAV
EKHTLVALRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDL
DASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVV
EDKKSIQLKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTD
EDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITE
ARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPD
AYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAF
SIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNF
ASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMH
AFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYS
SEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDL
QKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAM
GNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSH
KFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
>Q922S4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mus musculus|Swiss-Prot
MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEPPPQPCADSLQDALLSLGAVIDIAG
LRQAARDALSAVLPKVETVYTYLLDGESRLVCEDPPHELPQEGKIREAVISQKRLSCNGL
GPSDLLGKPLARLVAPLAPDMQVLVIPLLDKETGSVAAVILVHCGQLSDSEEQSLQVVEK
HALVALRRVQALQQRRPEAVQNTSVDASEDQKDEKGYTDHDRKILQLCGELFDLDATSLQ
LKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTMGRLGQVVEDKQC
IQLKDLTSDDVQQLQNMLGCELQAMLCVPVISRATDQVVALACAFNKLGGDFPTSSFTDE
DEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEA
RNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDA
YAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFS
IYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFA
NFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHA
FSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSS
EGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQ
KMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMG
NRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHK
FTIRGLPSNNSLDFLDEEYEVPDLDGTRAPVNGCCSLEG
>Q01062|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rattus norvegicus|Swiss-Prot
MVLVLHHILIAVVQFLRRGQQVFLKPDEPPPQPCADSLQDALLSLGAVIDIAGLRQAAKD
ALSAVLPKVETVYTYLVDGESRLVCEDPPHELPQEGKIREAVISRKRLSCDGLGPSDLLG
KPLARLVAPLAPDTQVLVIPLLDKETGTVAAVILVHCGQLSDSEEQSLQVVEKHALVALQ
RVQALQQRRPEAVQNTSADPSEDQKDEKGYTAHDRKILQLCGELYDLDATSLQLKVLRYL
QQETQATHCCLLLVSEDNLQLSCKVIGEKVLGEEVSFPLTMGRLGQVVEDKQCIQLKDLT
SDDVQQLQNMLGCELRAMLCVPVISRATDQVVALACAFNKLGGDFFTDEDERAIQHCFHY
TGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSV
FLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVD
DSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSL
LYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPE
DDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLY
KNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFA
QAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNN
KQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREK
AYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNS
LDFLDEEYEVPDLDVTRAPVNGCCSLEG
>P30645|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Caenorhabditis elegans|Swiss-Prot
MLELRRNSSPSSAHPSPQTNCQNSQRGDGLHHHHHEAASGSTCCGGMTVFTGANAAKSSN
EPAGSASPTVWRKTSHPPLHFNNNETRNRNLQMQLKNRGTKDDWGASLRYDIEEPTSSGL
LELLPDVPIVRKLSRPLVKMDDQDDACSVASNESDRTVLSPLVPMSIFDQFLCLTNNLSA
LISCIIAEAKKNTEAEDYAVFLHDEDNKQMVLFNNETMLMTGKKFDMGYGIVGKVASTMR
TMNIRDVSRCPFFNEEIDEQFSIKARNLIAFPLIDSSCSLIGVIVLYNKENGFSRHDEKY
IKRFSYFVANSIAHAILAKQIEEVRTRIHMVEEFKIQGEDAVIEEVDIMRLVNDPLRDWR
YFSQNFADFSFPPRSVGENHFHRASMMFFEDLGFSMLYKLNKRKLSYLVLRVSAGYRPVP
YHNWSHAFAVTHFCWLTLRTDAIRRALSDMERLSLLIACLCHDIDHRGTTNSFQMQSLQK
TPLSVLYSTEGSVLERHHFAQTIKLLQQEECSILENLPAADFRTIVNTIREVILATDISA
HLRKQERIKTMISEGYNPMSFDHRYLLMCLVMTASDLSDQAKNFHNAKRIAENIYLEFFA
QGDLELQLGVKPLEMMDRTNAYVPTVQIDFLFKIGVPVFQLLASVVPEGRTTSEAIDANH
LCWVALDEEVRNNPSATNTLEYLRDENLERRIYDRVRKQDPRAAEIASKRFEPVYANGSV
PQTQDILDHRFDGYDKKYQIGCSGGQNQSNGKQQQIRSLQKIRSKTSEDDALLKPMDNGG
SVAASSTRRGSRTPRRLWRRARQLISSMSSSCASCSPLPSRRQVSEDSESC
>Q14432|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Homo sapiens|Swiss-Prot
MAVPGDAARVRDKPVHSGVSQAPTAGRDCHHRADPASPRDSGCRGCWGDLVLQPLRSSRK
LSSALCAGSLSFLLALLVRLVRGEVGCDLEQCKEAAAAEEEEAAPGAEGGVFPGPRGGAP
GGGARLSPWLQPSALLFSLLCAFFWMGLYLLRAGVRLPLAVALLAACCGGEALVQIGLGV
GEDHLLSLPAAGVVLSCLAAATWLVLRLRLGVLMIALTSAVRTVSLISLERFKVAWRPYL
AYLAGVLGILLARYVEQILPQSAEAAPREHLGSQLIAGTKEDIPVFKRRRRSSSVVSAEM
SGCSSKSHRRTSLPCIPREQLMGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITDL
LADPSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPVTSLSENYTCSDSEESSEKDKLA
IPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSTSIKLQEAPSSSPDSWN
NPVMMTLTKSRSFTSSYAISAANHVKAKKQSRPGALAKISPLSSPCSSPLQGTPASSLVS
KISAVQFPESADTTAKQSLGSHRALTYTQSAPDLSPQILTPPVICSSCGRPYSQGNPADE
PLERSGVATRTPSRTDDTAQVTSDYETNNNSDSSDIVQNEDETECLREPLRKASACSTYA
PETMMFLDKPILAPEPLVMDNLDSIMEQLNTWNFPIFDLVENIGRKCGRILSQVSYRLFE
DMGLFEAFKIPIREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLSTVIN
DHGSTSDSDSDSGFTHGHMGYVFSKTYNVTDDKYGCLSGNIPALELMALYVAAAMHDYDH
PGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLINLDHVEFKHFRFL
VIEAILATDLKKHFDFVAKFNGKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKEL
HLQWTDGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSAG
LMPGKWVEDSDESGDTDDPEEEEEEAPAPNEEETCENNESPKKKTFKRRKIYCQITQHLL
QNHKMWKKVIEEEQRLAGIENQSLDQTPQSHSSEQIQAIKEEEEEKGKPRGEEIPTQKPD
Q
>Q9Z0X4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mus musculus|Swiss-Prot
MAVRGEAAQDLAKPGLGGASPARVARGNHRHRGESSPSPRGSGCCWRALALQPLRRSPQL
SSALCAGSLSVLLALLVRLVGGEVGGELEKSQEAAAEEEEEEGARGGVFPGPRGGAPGGG
AQLSPWLQPAALLFSLLCAFFWMGLCLLRAGVRLPLAVALLAACCAGEALVQLSLGVGDG
RLLSLPAAGVLLSCLGGATWLVLRLRLGVLMVAWTSVLRTVALVSLERFKVAWRPYLAYL
AAVLGLLLARYAEQILPQCSGPAPPRERFGSQLSARTKEEIPGWKRRRRSSSVVAGEMSG
CSGKSHRRTSLPCIPREQLMGHSEWDHKRGPRGSQSGTSITVDIAVMGEAHGLITDLLAD
PSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPTVTFSENYTCSDSEEGLEKDKQAISK
RLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKPHEAPSPSAVNPDSWN
APGLTTLTKSRSFTSSYAVSAANHVKAKKQNRPGGLAKISPVPSPSSSPPQGSPASSPVS
NSASQQFPESPEVTIKRGPGSHRALTYTQSAPDLSPQIPPPSVICSSCGRPYSQGNPADG
PSERSGPAMLKPNRTDDTSQVTSDYETNNNSDSSDILQNEEEAECQREPQRKASACGTYT
SQTMIFLDKPILAPEPLVMDNLDSIMDQLNTWNFPIFDLMENIGRKCGRILSQVSYRLFE
DMGLFEAFKIPVREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLPSVIG
DHGSASDSDSDSGFTHGHMGYVFSKMYHVPDDKYGCLSGNIPALELMALYVAAAMHDYDH
PGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRFL
VIEAILATDLKKHFDFVAKFNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKEL
HLRWTEGIASEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCHSYDSAG
LMPGKWVDDSDDSGDTDDPEEEEEEAETPHEDEACESSIAPRKKSFKRRRIYCQITQHLL
QNHMMWKKVIEEEQCLSGTENQSLDQVPLQHPSEQIQAIKEEEEEKGKPRAEETLAPQPD
L
>Q62865|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rattus norvegicus|Swiss-Prot
MAVRGEAAQDWAKPGLRGPSPAPVARGDHRCRGGSPSSPRGSGCCWRALALQPLRRSPQL
SSALCAGSLSVLLALLVRLVGGEVGGELESSQEAAAEEEEEEGARGGVFPGPRGGAPGGG
AQLSPWLQPAALLFSLLCAFFWMGLCLLRAGVRLPLAVALLAACCAGEALVQLSLGVGDG
RLLSLPAAGVLLSCLGGATWLVLRLRLGVLMVALTSALRTVALVSLERFKVAWRPYLAYL
AAVLGLLLARYAEQLLPQCSGPAPPRERFGSQSSARTKEEIPGWKRRRRSSSVVAGEMSG
CGGKSHRRTSLPCIPREQLMGHSEWDHKRGSRGSQSGTSVTVDIAVMGEAHGLITDLLAD
PSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPTVTFSENYTCSDSEEGLEKDKLAIPK
RLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKPHEAPSPSAVNPDSWN
APVLMTLTKSRSFTSSYAVSAANHVKAKKQNRPGGLDKISPVPSPSSSPPQGSPTSSPVS
GIASVQFPESPEVTTKRGPGSHRALTYTQSAPDLSPQIPPSPVICSSCGRPYSQGNPADG
PSERSGPAMQKPNRTDDTSQVTSDYETNNNSDSSDILQNDEEAECQREPLRKASACGTYT
PQTMIFLDKPILAPEPLVMDNLDSIMDQLNTWNFPIFDLVENIGRKCGRILSQVSYRLFE
DMGLFEAFKIPVREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLPSVIG
DHGSASDSDSDSGFTHGHMGYVFSKAYHVPDDKYGCLSGNIPALELMALYVAAAMHDYDH
PGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRFL
VIEAILATDLKKHFDFVAKFNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKDL
HLRWTEGIASEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCHSYDSAG
LMPGKWVDDSDDSGDTDDPEEEEEEAETPHEEETCENSEAPRKKSFKRRRIYCQITQHLL
QNHMMWKKVIEEEQCLSGTENQAPDQAPLQHSSEQIQAIKEEEEEKGKPRAEETLAPQPD
L
>Q13370|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Homo sapiens|Swiss-Prot
MRRDERDAKAMRSLQPPDGAGSPPESLRNGYVKSCVSPLRQDPPRGFFFHLCRFCNVELR
PPPASPQQPRRCSPFCRARLSLGALAAFVLALLLGAEPESWAAGAAWLRTLLSVCSHSLS
PLFSIACAFFFLTCFLTRTKRGPGPGRSCGSWWLLALPACCYLGDFLVWQWWSWPWGDGD
AGSAAPHTPPEAAAGRLLLVLSCVGLLLTLAHPLRLRHCVLVLLLASFVWWVSFTSLGSL
PSALRPLLSGLVGGAGCLLALGLDHFFQIREAPLHPRLSSAAEEKVPVIRPRRRSSCVSL
GETAASYYGSCKIFRRPSLPCISREQMILWDWDLKQWYKPHYQNSGGGNGVDLSVLNEAR
NMVSDLLTDPSLPPQVISSLRSISSLMGAFSGSCRPKINPLTPFPGFYPCSEIEDPAEKG
DRKLNKGLNRNSLPTPQLRRSSGTSGLLPVEQSSRWDRNNGKRPHQEFGISSQGCYLNGP
FNSNLLTIPKQRSSSVSLTHHVGLRRAGVLSSLSPVNSSNHGPVSTGSLTNRSPIEFPDT
ADFLNKPSVILQRSLGNAPNTPDFYQQLRNSDSNLCNSCGHQMLKYVSTSESDGTDCCSG
KSGEEENIFSKESFKLMETQQEEETEKKDSRKLFQEGDKWLTEEAQSEQQTNIEQEVSLD
LILVEEYDSLIEKMSNWNFPIFELVEKMGEKSGRILSQVMYTLFQDTGLLEIFKIPTQQF
MNYFRALENGYRDIPYHNRIHATDVLHAVWYLTTRPVPGLQQIHNGCGTGNETDSDGRIN
HGRIAYISSKSCSNPDESYGCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQ
AVLYNDRSVLENHHAASAWNLYLSRPEYNFLLHLDHVEFKRFRFLVIEAILATDLKKHFD
FLAEFNAKANDVNSNGIEWSNENDRLLVCQVCIKLADINGPAKVRDLHLKWTEGIVNEFY
EQGDEEANLGLPISPFMDRSSPQLAKLQESFITHIVGPLCNSYDAAGLLPGQWLEAEEDN
DTESGDDEDGEELDTEDEEMENNLNPKPPRRKSRRRIFCQLMHHLTENHKIWKEIVEEEE
KCKADGNKLQVENSSLPQADEIQVIEEADEEE
>Q61409|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mus musculus|Swiss-Prot
MRKDERERDAPAMRSPPPPPASAASPPESLRNGYVKSCVSPLRQDPPRSFFFHLCRFCNV
EPPAASLRAGARLSLGVLAAFVLAALLGARPERWAAAAAGLRTLLSACSLSLSPLFSIAC
AFFFLTCFLTRAQRGPGRGAGSWWLLALPACCYLGDFAAWQWWSWLRGEPAAAGRLCLVL
SCVGLLTLAPRVRLRHGVLVLLFAGLVWWVSFSGLGALPPALRPLLSCLVGGAGCLLALG
LDHFFHVRGASPPPRSASTAEEKVPVIRPRRRSSCVSLGESAAGYYGSGKMFRRPSLPCI
SREQMILWDWDLKQWCKPHYQNSGGGNGVDLSVLNEARNMVSDLLIDPSLPPQVISSLRS
ISSLMGAFSGSCRPKINSFTPFPGFYPCSEVEDPVEKGDRKLHKGLSGRTSFPTPQLRRS
SGASSLLTNEHCSRWDRSSGKRSYQELSVSSHGCHLNGPFSSNLFTIPKQRSSSVSLTHH
AGLRRAGALPSHSLLNSSSHVPVSAGSLTNRSPIGFPDTTDFLTKPNIILHRSLGSVSSA
ADFHQYLRNSDSNLCSSCGHQILKYVSTCEPDGTDHPSEKSGEEDSSVFSKEPLNIVETQ
EEETMKKACRELFLEGDSHLMEEAQQPNIDQEVSLDPMLVEDYDSLIEKMNNWNFQIFEL
VEKMGEKSGRILSQVMYTLFQDTGLLETFKIPTQEFMNYFRALENGYRDIPYHNRVHATD
VLHAVWYLTTRPIPGLPQIHNNHETETKADSDGRLGSGQIAYISSKSCCIPDMSYGCLSS
NIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLYLS
RPEYNFLLNLDHMEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDVNSNGIEWSSEND
RLLVCQVCIKLADINGPAKDRDLHLRWTEGIVNEFYEQGDEEAALGLPISPFMDRSSPQL
AKLQESFITHIVGPLCNSYDAAGLLPGQWIETEEGDDTESDDDDDDDDGDGGEELDSDDE
ETEDNLNPKPQRRKGRRRIFCQLMHHLTENHKIWKEIIEEEEEKCKAEGNKLQVDNASLP
QADEIQVIEEADEEEEQMFE
>Q63085|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rattus norvegicus|Swiss-Prot
MRKDERERDTPAMRSPPPPPPPATATAASPPESLRNGYVKSCVSPLRQDPPRSFFFHLCR
FCNVEPPAASLRAGARLSLAALAAFVLAALLGAGPERWAAAATGLRTLLSACSLSLSPLF
SIACAFFFLTCFLTRAQRGPDRGAGSWWLLALPACCYLGDFAAWQWWSWLRGEPAAAAAG
RLCLVLSCVGLLTLAPRVRLRHGVLVLLFAGLVWWVSFSGLGALPPALRPLLSCLVGGAG
CLLALGLDHFFHVRGASPPPRSASTADEKVPVIRPRRRSSCVSLGESAAGYYGSGKMFRR
PSLPCISREQMILWDWDLKQWCKPHYQNSGGGNGVDLSVLNEARNMVSDLLIDPSLPPQV
ISSLRSISSLMGAFSGSCRPKINSFTPFPGFYPCSEVEDPVEKGDRKLHKGLSSKPSFPT
AQLRRSSGASGLLTSEHHSRWDRSGGKRPYQELSVSSHGCHLNGPFSSNLMTIPKQRSSS
VSLTHHAGLRRAGALPSPSLLNSSSHVPVSAGCLTNRSPVGFLDTSDFLTKPSVTLHRSL
GSVSSAADFHQYLRNSDSSLCSSCGHQILKYVSTCEPDGTDHHNEKSGEEDSTVFSKERL
NIVETQEEETVKEDCRELFLEGDDHLMEEAQQPNIDQEVLLDPMLVEDYDSLIEKMSNWN
FQIFELVEKMGEKSGRILSQVMYTLFQDTGLLETFKIPTQEFMNYFRALENGYRDIPYHN
RVHATDVLHAVWYLTTRPIPGLQQLHNNHETETKADSDARLSSGQIAYLSSKSCCIPDKS
YGCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASA
WNLYLSRPEYNFLLNLDHMEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDVNSNGIE
WSSENDRLLVCQVCIKLADINGPAKDRDLHLRWTEGIVNEFYEQGDEEATLGLPISPFMD
RSSPQLAKLQESFITHIVGPLCNSYDAAGLLPGQWIEAEEGDDTESDDDDDDDDDDDDDD
DEELDSDDEETEDNLNPKPQRRKGRRRIFCQLMHHLTENHKIWKEIIEEEEKCKAEGNKL
QVDNASLPQADEIQVIEEADEEEEQMFE
>Q8I0P7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Caenorhabditis elegans|Swiss-Prot
MSPGPPAVGGVSPPVMVPGSAPPFQPTHQYFQHHYHQTPPGKLRDRSPRLSAEMRKNRDT
ATSSPASSGVSIQQRRGSTTQNSGVGSIGLPVLGGRGRGVMSDGHMQRTFHEAMRQRRTS
LPANSLSLNGAKVTGSSLSEAKGLIADMLMNKELPGNVASCLRAVTMLLEQRPLPLNGLL
NDFGLPSVVENPYGGESMVVGASKPRISNITFSTVTSATGLPTVPAEPNKARSSSYWKTE
ASPSNNNEHETPVDLLRKISVSRKESGTHVDTVVTTIDGQRYDTRELDTDPDLAETAVWS
FPIFQMSRKHPQTILSRLTYNIFQQAELFRIFKVSPIKFFNFFHALEKGYWEIPYHNRIH
AADVLHGCYYLSAHPVRSTFLTPKTPDSVLTPPHPHHQHSSIMSQLSTLELMALFTAAAM
HDYDHPGRTNAFLVQVEDKKAILYNDRSVLENHHAAESWKLLNKPENHFIENLDPAEMKR
FRYLVLEYILATDLKQHFEIIMTFTERLTEIDVQVETDRLLIGKLLIKMADINSPTKPYG
LHRQWTDRICEEFYEQGDDERRRGLPITPYMDRGDAQVAKLQDSFIAHVVSPLATAMNEC
GLLPILPGLDTSELIINMEHNHRKWKEQIELENGGSYEAQITCNGGTAVNGVIEEESAST
SDSPDPRRDSPLDSDLSQ
>Q56686|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Aliivibrio fischeri|Swiss-Prot
MFKNKLAVLFTCLSVFSFSAQSGSFDTVTLGSKGGIQDGNLTAFLIKSEADSNFVMLDAG
SVVNGLIVSEQKGAFKDITVPDSSPYTKVGYLLKDRIKGYFISHAHLDHVAGLIISSPDD
SKKPIYGLAATNKDLMKNYFNWSAWPNFGNKGEGFKLNKYNYVDLQPGVWSPVAETTMSV
VSLPLSHSGGQSTVFILKDSEGDVFAYFGDTGPDEVEKSSAMRTAWSVLAPFVKQGKLKG
IIIEVSFTNETPDKSLFGHLTPNWLVKELSVLEDMNGKGSLKDLNVAISHIKYSLKNSED
PKVIIKKQLVEVNDLGVNFIFPEQGDSLQF
>Q8ZD92|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Yersinia pestis|Swiss-Prot
MKYLSIKSASDKIKSGLLKTGVILSFSLFSSLSTAAFEVVALGVDGGVSDGNLTSYLIRN
DSQPLYLGLDAGSVLPGIARALEKGHFAAITDAMAAPLTRQGYIFRQSINSYFISHAHLD
HVSGLIIGSPDDSKKTIYASADTIDVLRNYYFNWRVWPNFTDSGSGARLGTYRMQVVRPA
QSLSLGLTRLTGEMYPLSHDKSPSSMLLISSNNEFFAYFGDTGPDDVEKSKNLDTVWRKL
AEKVTQQQLKGMIIEVSYPNDVADNKLFGHMTPTWLLKELKKLEQYSGEGQPLKGLPVVI
SHIKPSFQQGQDVRKLILSELQQGNDMGIEFILMEQGDSQKFQ
>Q22000|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Caenorhabditis elegans|Swiss-Prot
MPRRRGSSSSSSAAGGSGGGGGFGFSSLRRELHLHNFFRTSSPSASSTSRTPPAALPPRT
SAVTIPGSNHKLTSSASSYHPPRELTVSTFSAGSATAADGLGGAHLTPSLSSSVHARRES
FLYRASDDLREASSLRPVSRASSIASNEHGHGDDLIVTPFAQLLASLRNVRSNLISITNI
QNSDDSRHANRSAKRPPLHNIELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASS
KFRKMLNKELSHFAESSKSGTQVSKFLITTYMDKEEDEPSIEIEVPTEVQGPSTSGPMTL
SILKKAQTAAMNKISGVRKLRAPSHDGHVPEYGVNCAREIAVHMQRLDDWGPDVFKIDEL
SKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRNNHYHNFIHAADVAQSMH
VLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHH
LAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVA
GNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLE
ISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQSRIPEE
PDTARTVTEDDEHK
>Q9N2V9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Caenorhabditis elegans|Swiss-Prot
MGDRSGVGGEEGEKSVLGASAHSQAGRRQQHTPAARRGAQRAPAATAAAASRPVFAMRWC
CGGSYSENGGGGGGSRGAPPTPLLTVAATSSSTAHDTFGPMQVKMLKTAVIVTEGTGESV
LLDSLRASGWICTVSFPTQATSDVESICPLAVFIDLRVPHPSQIAKDVSSVSTEEVLIVS
IAEKHISEKRRRALAQSNIIHHVTWNTRDVVLFDYVGRLANRIRALPALFAVLDETDQAV
EICDEQRVVQYVNRAYENVTGCIRSEVIGQPESEMRRKSLPRARGEEERRRSCDWKFIRV
PFANNSQFVYMKRSNTTGDTAAIFRDVSLKSLKSQTGGIEAPISEVLTMLRDVSARVDGE
PAQTIKDAMKVLSSHELYAPSINRFRDADRIATQYYDGLIRLHHPARQRKRSVVDAHREK
RGSHGERRRVSADVKNALENDNCWKFDILHLEKVSDHHALSQVGMKVFERWKVCDVLGCS
DDLLHRWILSIEAHYHAGNTYHNATHAADVLQATSFFLDSPSVAVHVNESHAVAALLAAA
VHDLDHPGRGNAYLINTRQSLAILYNDNSILENHHIALAFQLTLQHNANVNIFSSLSREE
FIQMRHAMVEMVLATDISRHFEYLAKFNKMHVTDVPEEQRDTNSLTICDMLVKCADISNP
AREWGLCQRWAHRIVEEYFEQTREEKEKGLPVTMEVFDRNTCNVPITQCGFIDMFAREAF
ATFTEFAKLGELSDQLESNYEKWKVMTSQWTPTHNTNLVL
>O25683|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Helicobacter pylori (strain ATCC 700392 / 26695)|Swiss-Prot
MMQVYHLSHIDLDGYACQLVSKQFFKNIQCYNANYGREVSARIYEILNAIAQSKESEFLI
LVSDLNLNLNEAEYLQDKIQEHRLQNKNIQIQLLDHHISGKEVAESFHWYFLDINRCATK
IVYEFLKKHYAILEPKNTTWLEPLVEMVNSVDIWDTQGYGFELGKVCMRMINQSSELNRF
MFDDENRNYKLKLLEEVKNYLFLENAPVAYDNDLFKLKKIALGGDPDAETMDNISSNAQT
HLLSLKKHDCSVYYQDKKGFLSYSMGGISVLANLFLTQNPDFDFYMDVNAKGNVSLRANG
NCDVCELSQMCFNGGGHRNASGGKIDGFRESFNYRDIKEQIEEIFNNA
>P14100|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bos taurus|Swiss-Prot
MGSTATETEELENTTFKYLIGEQTEKMWQRLKGILRCLVKQLEKGDVNVIDLKKNIEYAA
SVLEAVYIDETRRLLDTDDELSDIQSDSVPSEVRDWLASTFTRKMGMMKKKSEEKPRFRS
IVHVVQAGIFVERMYRKSYHMVGLAYPEAVIVTLKDVDKWSFDVFALNEASGEHSLKFMI
YELFTRYDLINRFKIPVSCLIAFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGI
MHWLTELEILAMVFAAAIHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLM
QEEEMNVLINLSKDDWRDLRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPEGLDKAKTMSL
ILHAADISHPAKSWKLHHRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMVAQSQIGF
IDFIVEPTFSLLTDSTEKIIIPLIEEDSKTKTPSYGASRRSNMKGTTNDGTYSPDYSLAS
VDLKSFKNSLVDIIQQNKERWKELAAQGEPDPHKNSDLVNAEEKHAETHS
>P54750|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Homo sapiens|Swiss-Prot
MGSSATEIEELENTTFKYLTGEQTEKMWQRLKGILRCLVKQLERGDVNVVDLKKNIEYAA
SVLEAVYIDETRRLLDTEDELSDIQTDSVPSEVRDWLASTFTRKMGMTKKKPEEKPKFRS
IVHAVQAGIFVERMYRKTYHMVGLAYPAAVIVTLKDVDKWSFDVFALNEASGEHSLKFMI
YELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGI
MHWLTELEILAMVFAAAIHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLM
QEEEMNILINLSKDDWRDLRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPEGIDRAKTMSL
ILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMVAQSQIGF
IDFIVEPTFSLLTDSTEKIVIPLIEEASKAETSSYVASSSTTIVGLHIADALRRSNTKGS
MSDGSYSPDYSLAAVDLKSFKNNLVDIIQQNKERWKELAAQEARTSSQKCEFIHQ
>Q61481|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mus musculus|Swiss-Prot
MGSTDTDIEELENATYKYLIGEQTEKMWQRLKGILRCLVKQLEKGDVNVVDLKKNIEYAA
SVLEAVYIDETRRLLDTEDELSDIQTDSVPSEVRDWLASTFTRKMGMMKKKPEEKPKFRS
IVHAVQAGIFVERMYRKNYHMVGLTYPAAVIVTLKEVDKWSFDVFALNEASGEHSLKFMI
YELFTRYDLINRFKIPVSCLIAFAEALEVGYSKHKNPYHNLVHAADVTQTVHYIMLHTGI
MHWLTELEILAMVFAAAIHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLM
QEEEMNILVNLSKDDWRDLRNLVIEMVLATDMSGHFQQIKNIRNSLQQPEGIDRAKTMSL
ILHAADISHPAKTWKLHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMVAQSQIGF
IDFIVEPTFSLLTDSTEKIVIPLIEEASKSQSSNYGASSSSTMIGFHVADSLRRSNTKGS
VCDGSYAPDYSLSAVDLKSFKNNLVDIIQQNKERWKELAAQGELDLHKNSEELGNTEEKH
ADTRP
>Q01061|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bos taurus|Swiss-Prot
MELSPRSPPEMLESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEVNIEELKKNLE
YTASLLEAVYIDETRQILDTEDELQELRSDAVPSEVRDWLASTFTQQTRAKGPSEEKPKF
RSIVHAVQAGIFVERMFRRTYTSVGPTYSTAVLNCLKNVDLWCFDVFSLNRAADDHALRT
IVFELLTRHNLISRFKIPTVFLMTFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRT
GMVHCLSEIEVLAIIFAAAIHDYEHTGTTNSFHIQTKSECAILYNDRSVLENHHISSVFR
MMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKSMKTALQQLERIDKSKAL
SLLLHAADISHPTKQWSVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQI
GFIDFIVEPTFSVLTDVAEKSVQPTGDDDSKSKNQPSFQWRQPSLDVEVGDPNPDVVSFR
STWTKYIQENKQKWKERAASGITNQMSIDELSPCEEEAPASPAEDEHNQNGNLD
>Q64395|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cricetulus griseus|Swiss-Prot
MELSPRSPPEMLESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEVNIEELKKNLE
YTASLLEAVYIDETRQILDTEDELRELRSDAVPSEVRDWLASTFTQQTRAKGRRAEEKPK
FRSIVHAVQAGIFVERMFRRTYTAVGPTYSTAVHNCLKNLDLWCFDVFSLNRAADDHALR
TIVFELLTRHSLISRFKIPTVFLMSFLEALETGYGKYKNPYHNQIHAADVTQTVHCFLLR
TGMVHCLSEIEVLAIIFAAAIHDYEHTGTTNSFHIQTKSECAILYNDRSVLENHHISSVF
RMMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKSMKTALQQLERIDKSKA
LSLLLHAADISHPTKQWSVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQ
IGFIDFIVEPTFSVLTDVAEKSVQPLADDDSKSKSQPSFQWRQPSLDVDVGDPNPDVISF
RSTWTKYIQENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD
>Q01064|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Homo sapiens|Swiss-Prot
MELSPRSPPEMLEESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEINIEELKKNL
EYTASLLEAVYIDETRQILDTEDELQELRSDAVPSEVRDWLASTFTQQARAKGRRAEEKP
KFRSIVHAVQAGIFVERMFRRTYTSVGPTYSTAVLNCLKNLDLWCFDVFSLNQAADDHAL
RTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLL
RTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSV
FRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKPK
ALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQS
QIGFIDFIVEPTFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSLDVEVGDPNPDVVS
FRSTWVKRIQENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD
>Q01065|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mus musculus|Swiss-Prot
MELSPRSPPEMLESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEVNIEELKKNLE
YTASLLEAVYIDETRQILDTEDELRELRSDAVPSEVRDWLASTFTQQTRAKGRRAEEKPK
FRSIVHAVQAGIFVERMFRRTYTSVGPTYSTAVHNCLKNLDLWCFDVFSLNRAADDHALR
TIVFELLTRHSLISRFKIPTVFLMSFLEALETGYGKYKNPYHNQIHAADVTQTVHCFLLR
TGMVHCLSEIEVLAIIFAAAIHDYEHTGTTNSFHIQTKSECAILYNDRSVLENHHISSVF
RMMQDDEMNIFINLTKDEFAELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKSKA
LSLLLHAADISHPTKQWSVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQ
IGFIDFIVEPTFSVLTDVAEKSVQPLADDDSKPKSQPSFQWRQPSLDVDVGDPNPDVVSF
RATWTKYIQENKQKWKERAASGITNQMSIDELSPCEEEAPSSPAEDEHNQNGNLD
>Q01066|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rattus norvegicus|Swiss-Prot
MELSPRSPPEMLESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEVNIEELKKNLE
YTASLLEAVYIDETRQILDTEDELRELRSDAVPSEVRDWLASTFTQQTRAKGRRAEEKPK
FRSIVHAVQAGIFVERMFRRTYTAVGPTYSTAVHNCLKNLDVWCFDVFSLNRAADDHALR
TIVFELLTRHSLISRFKIPTVFLMSFLEALETGYGKYKNPYHNQIHAADVTQTVHCFLLR
TGMVHCLSEIEVLAIIFAAAIHDYEHTGTTNSFHIQTKSECAILYNDRSVLENHHISSVF
RMMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKSKA
LSLLLHAADISHPTKQWSVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQ
IGFIDFIVEPTFSVLTDVAEKSVQPLTDDDSKSKSQPSFQWRQPSLDVDVGDPNPDVVSF
RSTWTKYIQENKQKWKERAASGITNQMSIDELSPCEEEAPSSPAEDEHNQNGNLD
>Q14123|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Homo sapiens|Swiss-Prot
MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD
LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR
SDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS
GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV
HYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENH
HLSAAYRLLQDDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE
AIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS
TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSISSSDAKR
SGVKTSGSEGSAPINNSVISVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKAR
LAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEKSSGE
QQQNGDFKDGKNKTDKKDHSNIGNDSKKTDGTKQRSHGSPAPSTSSTCRLTLPVIKPPLR
HFKRPAYASSSYAPSVSKKTDEHPARYKMLDQRIKMKKIQNISHNWNRK
>Q64338|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mus musculus|Swiss-Prot
MESPTKEIEEFESNSLKHLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD
LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR
SDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIDALKDVDTWSFDVFSLNEAS
GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV
HYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENH
HLSAAYRLLQEDEEMNILVNLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE
AIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS
TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDESSQTGGTGQRRSSLNSINSSDAKR
SGVKSSGSDGSAPINNSVIPVDYKSFKATWTEVVQINRERWRAKVPKEEKAKKEAEEKAR
LAAEEKQKEMEAKSQAEQGTTSKGEKKTSGEAKSQVNGTRKGDNPRGKNSKGEKAGEKQQ
NGDLKDGKNKADKKDHSNTGNESKKTDGTKKRSHGSPAPSTSSTSRITLPVIKPPLRHFK
RPAYASSSYAPSVPKKTDDHPVRYKMLDQRIKMKKIQNISHHWNKK
>Q63421|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rattus norvegicus|Swiss-Prot
MTDTSHKKEGFKKCRSATFSIDGYSFTIVANEAGDKNARPLARFSRSKSQNCLWNSLIDG
LTGNVKEKPRPTIVQDTRPPEEILADELPQLDSPEALVKTSFRLRSLVKQLERGEASVVD
LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR
SDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIDALKDVDTWSFDVFSLNEAS
GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV
HYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENH
HLSAAYRLLQEDEEMNILVNLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE
AIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS
TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSINSSDAKR
SGVKSSGSEGSAPINNSVIPVDYKSFKATWTEVVQINRERWRAKVPKEEKAKKEAEEKAR
LAAEEKQKEMEAKSQAEQGTTSKAEKKTSGETKGQVNGTRTSKGDNPRGKNSKGDKAGEK
QQNGDLKDGKNKADKKDHSNTGNESKKADGTKKRSHGSPAPSTSSTSRLTLPVIKPPLRH
FKRPAYASSSYAPSVPKKTDDHPVRYKMLDQRIKIKKIQNISHHWNKK
>O18696|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Caenorhabditis elegans|Swiss-Prot
MNRARKTSSCGCFRSAFCLLKPSTSSASEEHGDSDKKLLSVQLITPRDEEEQTSSRSIKI
PPLDLNGLDCKKNAVAARRAGRRRTSEGGGVRGKGHFAEVVLDGLQRPVSLLRNQKEKSN
SDDNCQEKEPTSPSSSRKKSYDNAPALESLEKLRYILHQLNSGQLPLEDLKRNIEYAALV
LETAYMDETRRICDEDDDLAEVTPETVPDEVREWLAATFTRQNAGKKRDKPKFKSVANAI
RTGIFFEKLFRKQQVVQCPIPPEIAELMKEVCTWSFSPFQLNEVSEGHALKYVGFELFNR
YGFMDRFKVPLTALENYLSALEVGYSKHNNPYHNVVHAADVTQSSHFMLSQTGLANSLGD
LELLAVLFGALIHDYEHTGHTNNFHIQSQSQFAMLYNDRSVLENHHVSSCFRLMKEDDKN
ILTHLTRDEYKELRNMVIEIVLATDMSTHFMQIKTMKSMLSLPEGIDKNKALCLIVHACD
ISHPAKPWNLHERWTEGVLEEFFRQGDLEASMGLPYSPLCDRHTVHVADSQIGFIDFIVE
PTMVVCGELLVKMVEPLVSLPPTDSLFPPSVDGGDDKSPSNALSPLPDLRNSSTSPSSIR
RIPLNYAGKLDIPTPWMKFLHENKAHWKERAAKEEEERKIKEAAEAEAAAKQVEENKENG
VTTN
>P32782|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candida albicans|Swiss-Prot
MSFEITILGSSGGPLEGSTCSILLKPANISYHDIINDNLPDQVLCIDAGSGMGKLTEIIH
QETTTKTSYCNFLQYYPDCETVSYYYHPNVTITTPFSNFQPGRPILHTQNIFNNLQNYLI
SHSHLDHVCSVVINSAGFNKNMSNKILYGSHYTINAMQQHLFNGKVWPNMPSFKIVNLNY
LESNRSERIGIYTVKMFDLSHGEFNKLTEDKEDAQHHSNSNSNSNNIWGKRYDRRRSSIT
TIPQNTSGLIIKNSEALNHHYLSSAFLITLEVPCTTKEPPPSILVFGDFESDLTSKLSRN
LFIWKSIASLILRNQLKAIVLECSNCKEIAANELYGHLTPKLLIYELKQLEHECKQLDTA
TTSTEQPLLGLNVIVNHVKEPIADPNQESQLHDPRKRILAELNKLNEIEKLGCNISIALS
GTSIIV
>P9WP64|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)|Swiss-Prot
MHRLRAAEHPRPDYVLLHISDTHLIGGDRRLYGAVDADDRLGELLEQLNQSGLRPDAIVF
TGDLADKGEPAAYRKLRGLVEPFAAQLGAELVWVMGNHDDRAELRKFLLDEAPSMAPLDR
VCMIDGLRIIVLDTSVPGHHHGEIRASQLGWLAEELATPAPDGTILALHHPPIPSVLDMA
VTVELRDQAALGRVLRGTDVRAILAGHLHYSTNATFVGIPVSVASATCYTQDLTVAAGGT
RGRDGAQGCNLVHVYPDTVVHSVIPLGGGETVGTFVSPGQARRKIAESGIFIEPSRRDSL
FKHPPMVLTSSAPRSPVD
>P9WP65|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)|Swiss-Prot
MHRLRAAEHPRPDYVLLHISDTHLIGGDRRLYGAVDADDRLGELLEQLNQSGLRPDAIVF
TGDLADKGEPAAYRKLRGLVEPFAAQLGAELVWVMGNHDDRAELRKFLLDEAPSMAPLDR
VCMIDGLRIIVLDTSVPGHHHGEIRASQLGWLAEELATPAPDGTILALHHPPIPSVLDMA
VTVELRDQAALGRVLRGTDVRAILAGHLHYSTNATFVGIPVSVASATCYTQDLTVAAGGT
RGRDGAQGCNLVHVYPDTVVHSVIPLGGGETVGTFVSPGQARRKIAESGIFIEPSRRDSL
FKHPPMVLTSSAPRSPVD
>Q8YLG0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)|Swiss-Prot
MNEKLPISIAQITDIHLLASESQRLQGISTTESFLAVMKRLEELRPELDLLLMTGDLSDD
GTPESYENLQHYLNSLQIATYWLPGNHDCAIAMDKILNLGMVSRRKSFQRGNWNFILLNS
SVTDCVYGYLSATTLDWLDSELKMLPNNPTLIALHHPPLSVNSAWIDRSCLQNSQELFAV
IDRYPQVKLVLFGHIHQEFRRQRHNVHYLGSPSTCYQFQSQSTTFAINQELPGFRLLKLY
ADGTWTTKIERVPYSLPIEPTVTVSY
>A0A1I8G599|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Macrostomum lignano|TrEMBL
MVEEDAINKLMLVKNLQYAVEVLEAVYIEETKRLCNEDDDLPTVSPTEVPNEVRDWLAST
FTRTQSSMQQNKDKPRFRSVANAIRAGIMVERLSSASSITVPPNVVILLKAGLDTWAFDI
FELNEAADNHALKYIGAELLHKYNLISKFKINPSTLDNFLLKCEEGYSKWSNPYHNLLHG
ADVAQTCHYIMHESRLAHWLTDLDVFATVIAALIHDYEHTGTTNNFHINTNSELALLYND
KGVLENYHVSAVFSLMREDDYNILTGLTVEEFKEFRALVIEMVLNTDMSLHFQQIKSMKQ
LLSMPDKIDKSKVLSMVLHCADISHPGKPWEMHYKWTIALLEEFFRQGDREKKLEIQVSP
LCDRNTTLVAQSQ
>I4K4J2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas lactis|TrEMBL
MPSVSAVNPDAVLLVQLSDSHLFADADATLLGMNTRESLQRVVELVRAQQPAIDLILATG
DLSQDGTLASYQQFRDLTASLGAPARWIPGNHDEPQVMAQAAMHSDLLEPVVDIGNWRIT
LLDSAVPGSVPGYLQDAQLQLLAQALSEAPGRHHLVCFHHHPVPIGCAWMEPIGLRNPEA
LFAVLERFPQTKALLWGHVHQEIDSERNGVRLLASPSTCIQFAPGSEDFQVSEQAPGYRW
LRLHGDGRLETGVERVKGFAFTVDYGSNGY
>A0A1S8R095|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium beijerinckii|TrEMBL
MALYTISDLHLGFNVEKPMDIFGDKWKAHSDKIKENWLKKITEKDMVLIAGDISWSLKET
DSKYDLDWINELPGKKIISKGNHDYWWGSISKLNKMYENTKFLQNNFYTYEDYAICGTRG
WMCPGGDKYTSKDEKIYTREQIRLKLSLDAAKNSGFEKIIVMLHYPPTNDKFEESEFTRM
IKEYKVEKVIYGHLHGPILLGKVLNGYLDGVEYILTSADYLNFDPKKIL
>A0A7R9LIC0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oppiella nova|TrEMBL
RLLDEDDELSEVQPDAVPNEVREWLASTFTRSNNSQKRRPEDKPKFRSVAHAIRAGIMVD
RIYRRLAGATALHIPPDAALLLKGVDEWCFDVFALNDTCKGQVLRCLSADLLNRYGLIHK
FKIPSSNLENFLLQMEQGYTKYSNPYHNNLHAADVTQTVHYTLWATGLAQWLSDLEIFAT
LIAAIIHDYQHTGTTNNFHVMSGSDITLVYNDRSVLENYHISAAFKVMRESDSNILINLS
KEEYRYCLHCH
>A0A0R3R7X9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Brugia timori|TrEMBL
MTSQALLILTVSNYIESFQCNPEIRGLFQATSFFLDCPTVAHYVQEAHATAALIAAAVHD
LDHPGRGNAFLINTQQPLALLYNDQSVLENHHIALAFQLTLQSTTDINIFARLTREEFTT
LRQATVEMVLATDMSRHFEYLTKFQQVVSNLKDNEENENNISLTICRMLIKCADIGNPTR
EWELCEKWAMRIVEEYFDQTSEEREKGLPLTMELFDRNVCNVPLTQCGFIDMFAREAFTC
WTQFSNLPNLLTQLEMNYEKWRQKTADWNPSKNAHLCDNRTLTS
>A0A0S4WPP3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ralstonia solanacearum|TrEMBL
MHFLQLTDLHIKPPGRLAYRRVDTAAYLSRCVAHILAQPARPDAIVLTGDLVDAGAPDEY
AHLRALLAPLDAAGIRMLPVLGNHDARAAAHEAFADWLAPIPAEARDPQAFQYWTDIGEV
RLIVLDTLDTGAPGGRLGVPRLDWLHDALAAEPARPVVIAMHHPPFATGIGHMDVQSLAA
EDIPAFAQIVRAAGNVERILCGHLHRAIDVRFAGTVASTCPSPAHQVALDLDPEGAPGFV
MEPPAYRVHAWVPGQGLVSHLAYVGTFDGPHPFFEPDGRLID
>A0A1C0B839|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Aliarcobacter thereius|TrEMBL
MRLFHISHTDLDGYACQFLTNKVFSKSTFYNANYGLEVKQALKQALIDIEKHKDEKLLFI
ISDLNLTPQESAELDKNIDELKEFGCDITLQLLDHHISGKKSSEKYDWYFLDDKRCATKI
VFDYLKDNFDAKIDEYKELVDTINAVDIWLENEVENFEFGKVLMSSIIKAREINSILFAS
LDREYKFYILDKAKDYLNFEDRHIILDNDMHKIKKDFLKENKDDTLDNLSAKYLVKSLDT
IKDELTIVYNGQKGLMTYCLGSISIPANSFLRANSDYDFFIDINKKGNASFRADGKLDVS
QLAMKLANGGGHINASGCKFEDFVDSIYIQDIKKYIQNKLDNLK
>A8HRJ2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chlamydomonas reinhardtii|TrEMBL
DNPYHSATHAADVLQTLHVILHGAQLQAHYLNPLGLLAAYMAAIMHDYAHPGLTNDFLIA
TSDPLAVRYNDRSPLENHHAAASFAAMRRPELDALAPLSAEQRKEFRKLVIDMILATDMK
QHFALLSQFNTQHRLTAFKAADHKTERLLSLQLAIKVADLGHLGESLEVHKRWLTGLEEE
FFRQGDKEIEAGLPISPLFDRSKQGVSKSQVG
>A8JGI3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chlamydomonas reinhardtii|TrEMBL
MKAGLGNADGTSCPLCPLKVPSLDAPAIEVFNHYCSPRHSRGGSGNVASPARPRRGSVDL
PSGAQGVSDDPLTPASPWWAHIPPHSDGDLSTRSAPLGGIAGDVLSPRQSNCYGPATPGG
AGGSGAGPGARSRLAMGGGRHMQARRLSRSKAGTPADLLLSMLSNMLLGLTPDLRDVELA
RTMLLRHADPYQPLNLDTQMREANLDVERALALADEWKYDTWHLAEVTKGHALSCLGFYL
LHREGLISQFRIKPTKLLRSIEAGYADNPYHNSTHAADVLQTFHVLMRGAGLTTHYLDRV
GLLAAYFAAMVHDHGHPGLTADFLIATSDPLAVRYNDRSPLENHHGASFFSMLMQSDMNV
LAQLTQHEKNAFRKQVLDLVMATDMKQHFTLLSHFNTAHHLPAYNKEAGPWALVAEPAPT
TNQSGTEQASGGAARGAEGDIDGAEAAVSFTLLGTFDPTPLDDTERTLTLQVALKAADLG
HLGEELEVHKRWVRALEEEFFRQGDQELARGLPISPLFDRAKQGVSKSQVGFYDFIALPL
VHALASAFPGARPLLACYVANYDHWREAEKAAAAAAAAVAASAAAGRVFRA
>A0A3P7VRQ5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Haemonchus placei|TrEMBL
MCDTVVTTVDGQKFDTRDLDNDRGMAMVADWSLPIFEIAEKYSKTVLSRLTYTVFKQADL
FRIFKLSPIKFFNFFHALERGYWDIPYHNRVHAADVLHGCYYLTCHPVRPLIGPTTSPDS
LLPPPPPMAAPISASMSTLELMALYTAAAMHDYDHPGRTNAFLVAAEDKKAILYNDRSVL
ENHHAAESWRLLQLAENNFIETLDPAETKRFRYLVLEYILATDLKQHFEIIMTFNEKSSE
MELQNESDRLLMAKMVIKMADINSPTKPYSLHRQWTDRICEEFYEQGDEERRRGMPITPY
MDREDAQVAKLQDSFIAHVVSPLALAMNEAGLLPILPGLVEPEMIINLKHNHQKWLQEID
STAAEQVSTMGNGVIEEESSTSDSPDNRKCSPSLDSEVEVRQLTYLISFALKW
>A0A3G7H3R9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas chlororaphis|TrEMBL
MPSVSTLTTDDPVLLVQLSDSHLFAEADGTLLGMNTRDSLQRVIDLVLEQQPRIDLMLAT
GDLSQDGTLESYQLFRDMTRRIPAPARWIPGNHDEPQIMAQAATQSSLLAPVVDIGNWRI
TLLDSAVPGSVPGYLQDDQLQLLASALSEAPERHHLICLHHHPVSIGCAWMEPIGLRNPH
ALFAVLERFPQARAVLWGHVHQEIDRQQGSLRLLASPSTCIQFEPGSEDFKVGETAPGYR
WLRLLPDGRLETGVERVTGFDFEVDYGSDGY
>A0A378RMS8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Myroides odoratus|TrEMBL
MKRSEFLRTVALGTLATAIPFDVQADTSSLLKKKETLSFGIITDLHQDLTFDAPQRLQAF
VDEMNEKQVDFIIQLGDFCVPKKENQIILDIWNSFQGDAFHVIGNHEFDENKSLEQIMDF
FELKQNYYSFDRKGYHFVVLDGNGKIPGNDAARYPSYFHKAQLEWMEHDINSSPLPTIVF
IHQGLDHNGVHNREAVRILLDNCNKKAGYTKVKVVFSGHHHMDYTNVINGIHYVQINSAV
YRWLGEPYNNTSFPPEAYKKYPYLRNMGYYKEPLWAQVQITSDELKLTGKESPWYGDSPV
DLGEPIVSWNYVSVAKISDRLIKL
>A0A4Y7RUZ1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pelotomaculum sp. FP|TrEMBL
MGSKIKLTNSTGTKITNEELCTLGSQHAVITWVTPQQRADTSMYIGETPKHLKKQTFALD
SEFHYLEMYNLKPSTRYWYQVESNGVKGSLNSFTTLPSPKGKYLFSFAVMSDTHINYGEV
AEDINEIYFGKLVDYANPLLSQCILDSKRRNIDLAVITGDLTDTASSLQYLGLRNQLLPY
FGDTPYLLCPGNHDKYTKNSGLGEQGFLNNLTNREKTYTSMVFKDYLFLLIDSCKPDNNW
GDIDPVQMQWIESMLTTNKDRQAFLFLHHPCNGPDLWFGIKNSREFLRLTRSFPNIQGIF
CGHIHRNYVSVNRFMTGNRPYVEVPATVQFPCAYAIVQVYENGFAYNSYKVSRLDLSEMS
RERFILKKGGKAILTRYCLGRIGDRSFSYFNDQLFRPKQYEVSVTLDHTKANELYEHARA
IDGASLIPAYDTKKAKVILGRYDSLHLTTEAFRQKFFRYGAYARIMEVGNES
>A0A086LWC1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii RUB|TrEMBL
MAAHSPYLGRPGTFSAPDECWNEERVPSGISPADTIREIVLFQALRNAERWSARAHVLET
KTGKTPAVSVSGFGSADASEGQRAIGSKRATPGKEDSTKSSKDSPRSAFASSPPHAHGPG
ASTPPGPQSVCGASFWTQRRLLVRHKTYSPARFGISAEDERDEGEDRLSRDEGETGALAG
SPGFALGKRDRMRERKLKPPRRRSWMTVTENRKRREQEEQRRDDRSRVKENVLRGILKRE
KEEKKSNEGTRDGVRSSTCRHANPEHRTNREDRKGKTSGNHEMDENADRSRMSGTRKPGN
ETWGREKDLEDHQPHTCEMLPQENEITDIAEETERGRAVESAGTLSQKQARETKKREASK
EKGKGARRHAGESMQTSQMSLETELLHVEKRVCETV
>A0A5C5XC81|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rubinisphaera italica|TrEMBL
MPVHLVQHSRRQFLKTVGAGIVVCSSPSFANARPAVDGDLVYLLNDTHIGEKQPSDSPVP
SHLRQVVTELVDRKTQPSCVLINGDLALKDGQPGDYQHFAKLLRPLHEAQIETHLTLGNH
DNREAFYSILEDERPADPPVESRHISVVQTPKANFFLLDSLKETMITQGAIGGDQLSWLA
QALDAHATKPALIVAHHNPRLGGDPLHFPGGLIDSQPLWNILSARSHVKAYIHGHIHDRS
IFKHQGIHILNTPATSYVGNPATSTTGWTTARLSNEGVTLTTHTTDPQHSWNGETKILQW
RG
>A0A086QXD4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii MAS|TrEMBL
MGFAVALYKNYEQNPYHNFFHALNVAQVCCLLMALPDVAARFQPLDYFVLSVAALGHDLG
HPGANNLFVNRNDCLPSRLYQNRSVLENYHAALLFQILRYEL
>A0A0D2MNU5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Monoraphidium neglectum|TrEMBL
MAGLVQQIIPKIYDWDFNVFDVAGRSGSRPLFAVVMALLEDQGLLDGWKLDRATVARYFE
AVEAAYNNNPYHNNTHAADVTQTAAVIMRFTHDFLAMATAPPQQQQQLQQQHRAVVGVAP
ALAPLPPTAEEEEEEDRGLSRLERFCVIFASAVHDLGHPGVNNDFLIRTRDKQAVIYNDK
SVNENMHCARAFEVALEAEGCDIFGRFSAEEYAKARSLIVGMVLSTDMAVHFDLLNKFNA
ALEACPEPRLWGDKERGLVLQMLVHLADLANPARPFFLAAAWAERVVTEFLRQGDAEAAR
GLGVTPFCDRHKVCMPAAQQGFVKMFAGVSWGEAGEGR
>A0A0J1BEJ4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodopirellula islandica|TrEMBL
MLPRPTAASVQSAHMVVPDHSCRPALESHPISCRSRLVPIHQIPQSRRGFLKTTAIGGGT
ALLMSATQTVSAASDQATVLALLSDTHIPSSPDLTARGTNMTENLQQVISEVLTRKTRPS
DLIVNGDCAYLKGLPGDYQNFVRCLAPAEQAGIALHLTMGNHDDRQPLYAALSGQRPTAT
AVMSKHVSVLETPHANLFLLDSLFRVNVVTGELGDAQIDWLAEQLDARSNKPAIVMTHHT
PQFTAPKEGKPWNGISDTEKLLKVLDSRKHVKAYLYGHSHHWSHSQRGHFHMINLPPVAY
LFNKTSPNGWVEAVLTDDAMRLQLQTLDPKHPLAGETIKVSFTS
>A0A2I3RCF3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pan troglodytes|TrEMBL
MANPVPVQRSHLQGPILRLRYMVKQLENGEINIEELKKNLEYTASLLEAVYIDETRQILD
TEDELQELRSDAVPSEVRDWLASTFTQQARAKGRRAEEKPKFRSIVHAVQAGIFVERMFR
RTYTSVGPTYSTAVLNCLKNLDLWCFDVFSLNRAADDHALRTIVFELLTRHNLISRFKIP
TVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVVGALEMILLSRLYSH
FHFSSSECAILYNDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRALVIEMVLAT
DMSCHFQQVKTMKTALQQLERIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFR
QGSWPCQLHALPSPPDNSKTSLRHCSSTAGFIDFIVEPTFSVLTDVAEKSVQPLADEDSK
SKNQPSFQWRQPSLDVEVGDPNPDVVSFRSTWVKRIQENKQKWKERAASGIANQMSIDEL
SPCEEEAPPSPAEDEHNQNGNLD
>A0A7R9HPG2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Timema monikensis|TrEMBL
MDVWESSAPYERLRYQIPRLNRAVTMHDKYPTLRRLADEDDELSEVQPDAVPPEVREWLA
STFTRQLATTRRKNDEKPKFRSVAHAIRAGIFVDRIYRRVSNTALMQFPPEVVKVLKTLD
DWSFDVFALSESATSQPVKYLGYDLLNRYGMIHKFKVPPVTLETFLNKVEEGYCRHRNPY
HNNLHAADVAQTVHYMLCQTGLMNWLTDLEIFATLVAAIIHDYEHTGTTNNFHVMSGTDT
ALLYNDRAVLENHHISASFSVDKSKALSLVLHCCDISHPAKRWDLHHKWTMQLLEEFFIQ
GDKERELGLPFSPLCDRNNTLVAESQIGFIEFIVEPSMGVCSDMLESILGPIHSSCKPQI
GEGARESISEEGELDRTKNGATSSPERPGRFKIKKPWVGCLIENKTTWKDQAVKG
>A0A086JL75|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii FOU|TrEMBL
MGRLRSAATRMATRAGRRNEADGALEEGNDLEGRPGAGEASTPHNRFGLVGLSEPRDDLR
RPLDAEPFVPKHSAGEFPGSCKFQGRSARLSLNSTVLGEDCPMRLRTDGASPDMKVEEGE
SGTGVPLPAVSRLCTSPRVLWGLNSGLSLLAGSVLQGAGTEKAGRNLSTKVSFEATRKDS
RRDSMRLAFSKQGANGEAGRLQSVAVREEPERLVSTKVRDVCTRSSPHESSSSRRAVTIR
VDGSVVDSVELGCRTWNGCETPTERGVKERKKERKKEREMEEKEEEEMLDTDTPPHLRGR
GTLEALYLKWSKHSVYKFFSEEDRKYFDMATTGIPCYFSSKNLERSYALYRCPALSGYLL
LFHTAWIICTWTIYCLCVLTRPAVTSSRRMVAPFVVSWMISALSIFVVFLWRQTGGVAVE
RFNRKEKELRKAEEGAVPMYEAYHWRPCFTEDFGTASIGLATITPVALAAAVAVWIGLDP
YIINDYGESSSRLAPPLLDTSFGLAGFVASQGYIAFSVLFLTVSVICSGIRLRKMLYVAV
GNMISVLTALISFAFAYKDYTL
>A0A1V5VEQ3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|bacterium ADurb.Bin236|TrEMBL
MTRREFISGTLLGAGACLLGGTSLASALAPSAAPPDSVSFVHFTDTHLNPARDYSHCRMI
KDSLALLEDAVSSVNTMKNIDFVIFTGDMIDSPTEKLVETFARAANRLQVPWFWSIGNHD
VGPGGMKVPKMVEALNKHNPHFTAPAPRYSFTVNGFLFVSMCGAIDNAVTAAARFPEDEF
QFLDERLRADASRPAILFQHFPIVYPFKSATHVVLNQQEYFGLIDSRPNVKAVFSGHYHA
ARLSERNGVAHVSTPALIQYPNEIRKTTVTRAAQGVKFDFEMIPTRLRNIRESSRAACSS
SALLEGKPSDRTASMSVK
>A0A086K063|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii FOU|TrEMBL
MNRRSLLALTYNDNSVLEQFHSSVAFFLLHHHHLLLPSSPHCSTLERTRKRRSANHEAAA
PSRKNEAGTQISTREASEAGNLELVGEDAAEQERGESVCAESLCDRIEREEYYRDFRKEV
IELIVHTDMTKHFSLLALFKVKRQTGGLDIVNNEEDRSMLLKMLLKAADIGHATKAFDFH
FFLSCCLIEEFHRQGDEEKKRGMVISPLCDRQQELRQIFSSQAGFLQVVCLDFFSELADV
ARDLEHAQTLQLQSASAGPEGASGPRPASSGSRSHQRRDCAASRASGEEGRNFEASKDRQ
LVSRSFSSSASVPRLSSRKGFRRCLSTAEQPHPPLPSLTPSSPCRFALSSSAAYASGSLP
SLLLSGAQSEDAGNRRAPPRLHPFRPLSGRGKTEPSSTALVREALPPQAASAAAAVSCVC
HQASVTGTSVFKRPCVGDIGSPPGLQRRLPAEETKAAAADSATGIDPASAGEKRRVFSSG
VSHPFALPHGGPESRGSEKSGNACMRSLSSFFRGPKARKEDTDDDARARQKRSQTLPSSL
SLVSASRCNGAQAFANRLPVRHCLDAEEPGGGRGGQDAPTGHRRILSRGGSLPPNYRSSE
GDQGGPKSQGESAGTIGALRAEPTRTGETSDGKLRGTEAATGAKNRNAWSCPCETEESAA
TEGRESKDREAEAEAEEEERLCQGDFCEFCRNNSWSISRAASQHIASSTASAHSSSLLEA
CVTQIQRNKHAWEAMAEEQREPPRLLPADLLFGPFPRDGVGGLVRRHLKRWSTISPS
>A0A1R4HEN5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Crenothrix polyspora|TrEMBL
MTKPTNCTTLLHVTDSHILSSPDATLLGVNTAHYFQKIIKQAFAKHHFDLILLTGDLAQD
PCVASYQYIRTALDAYDTPCICLPGNHDAYDIMQQVFNTGSINCRKQVLFNNWQLISLNS
QIIGATGGYLSHEELVFLDECLAKYPKHYALLAMHHHCLETQSIWMDTMIVANRQQLFAT
ISRYPQVKAIVHGHIHQTLEAKVGAVQLWGTPSTCFQFKPRAKEFDLDDTSPGYRIIRLY
DDGQIESEVVRLAEALAGLQIHTHGY
>A0A2H6JBV1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|bacterium BMS3Bbin12|TrEMBL
MFARQKAGRFPSPAHGDPVPLHWGAVRDRAGWPSGPPAGSLRVLQVTDTHLYRDADRTLL
GINTQRSLEQVLEQARYEHGPADLVLATGDLVHDHAREGYARLRALLHSLGAPGYWLPGN
HDDPQVMREVLAGAGACDPRSVRVGRWQIVLLDSRIAGGGDAGRVSHAGLRSLDEDLGRY
PDHHALVCLHHPPVPIGSRWMDAIGLQNAAELFAVLDRHPQVRAVLCGHIHQEFETRRAG
VRILGSPSTCFQFRRRSDEFALDSAAPGYRWLALHADGGIDTGVGYLEDFTAAVDMASTG
Y
>A0A3G7BBT9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas chlororaphis subsp. piscium|TrEMBL
MPSASTLTTDDPVLLVQLSDSHLFAEADGTLLGMNTRDSLQRVIELVLEQQPRIDLMLAT
GDLSQDGTLESYQLFRDMTRQIPAPARWIPGNHDEPQIMAQAAIQSSLLAPVVDIGNWRI
TLLDSAVPGSVPGYLQDEQLQLLASALSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPH
ALFAVLERFPQARAVLWGHVHQEIDRQQGPLRLLASPSTCIQFEPGSEDFKVGETAPGYR
WLRLLPDGRLETGVERVTGFDFEVDYGSDGY
>A0A165T568|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudovibrio axinellae|TrEMBL
MNFAQLTDTHLMADGQLAYSCVDTATHLCAAIDHLNAFRPRLDFVIISGDLVDLGDAEEY
KLFRQKIEQLEMPYYVIPGNHDHRDVMRQAFADHEYLTKDGALQFSIEKEGLRIIGLDTT
IPGEHDGHFDANKQAWLREELSAHKEQPTLVFMHHPPFQTGIAHMDEIMLTRANEDFWPV
LQGQSQVRHIACGHVHRAIETFKGGIPINVCPSSAHQVTLDLKTVGEATFIMDPPAVRIF
VWDGVHLINHLSFIGDYGKPRSFTDGAELFAL
>A0A238D5T1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thiomonas delicata|TrEMBL
MILCQISDLHIKRKGALAYGRVDTAGFLARCLERIRALRPLPDAVVITGDLVDRGDAEEY
AHLRELLAALPMPHYLLVGNHDSRQALRAAFPDHAYLGSADGFVQYAADLGPCRLVALDT
QDPPHSGGRLCEARLRWLEQELERADRQPVILAMHHPPFVTGIGHMDAIGLPAADCARLG
AVVARHPNIERVLCGHLHRPIQHRFAGTLASTCPSPAHQVALDIRPDAPAAYRMEPPAFQ
IHAWLPGTGLVSHLVPVDESPGPYPFFHQDGQLID
>A0A174CDE6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bacteroides finegoldii|TrEMBL
MLRKNLYWLLSCLFLAGCGMIDYHPYDVHISGETNVNAHNMEKIEANCKGKTEIHFAVMG
DSQRWYDATEDFVKEINKRDDIDFVIHGGDMSDFGVTKEFLWQRDIMNGLKVPYVALIGN
HDCLGTGEETYKTVFGPTNFSFIAGNVKFVCLNTNALEYDYSEPIPNFTFMEEEITNRSD
EFEKSVVCMHARPFTGVFNDNVAKVFQHYVTQYKGLQFCTAAHTHHFRDDILFDDGIHYI
TSDCMDYRTYLVFTIAPGSTSENPDYELFEY
>A0A3S4I352|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salmonella bongori|TrEMBL
MYSALQDAGISPAKRVLIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLTDAPERQTL
LLLHHHPLPAGCSWLDQHSLRNAAELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLAS
PSTCVQFKPHCANFTLDTIAPGWRTLELHANGLLETEVHRLQDTRFRPDTASEGY
>A0A0C2GJ68|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ancylostoma duodenale|TrEMBL
MPGPHGDRRRVSADVKNALENDSDWTYDILQLEKVTEHHALTQLGFKIFDRWKVADALSC
NEDILHRWLCTIEAHYHAGNAYHNATHAADVLQATSYFLDSPTVAAHISENHAIAAILAA
AVHDLDHPGRGNAFLINTRQSLAVLYNDHSVLENHHVALAFQLTLQQNSNVNIFSNLSRE
EFTSMRHAMVEMVLATDISRHFEYLVKFNKVSRLSLRGAYTLCESIEFQMNVVDVPDDAR
DGNSLTICNMLVKCADISNPTREWSLCQKWAYRIVEEYFDQTKEEREKGLPVTMEVFDRK
TCNVPLTQCGFIDMFVREAFANFSEFANLGHLSAQLEANYEQWKSQTSSWTPANNVSLHT
>A0A1R4I333|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Halomonas sp. JB380|TrEMBL
MLIAHLSDLHVFTTQSETGESRADIAQVVERIVTDLVSLSPPPDLVVISGDLADGGTEDD
YRLIRRLLAPLDMPILAVPGNHDRREAMRAVLGDRLAGLQPGKFLHSRVEADGVTLLGLD
SIIVGKPQGALCSERLGWLENQLRHTQPLTFLVMHHPPFMTGNPHWDDYSLIEGRERFKT
IIGASPKRILCGHIHQPFHTLWGQHYSAIAGSPAFQYNLVPGSQAKPTLGDMPYCYPLHD
CQPDGSILVHLRHIA
>A0A2X3JCG1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cedecea neteri|TrEMBL
MDDFATRLLFIDSSLAGHSKGWLTENTVAWLEAQLTAGGDRPTAVFMHHPPLPLGNAQMD
KIACENGHLLLDLVARFPSLVRIFCGHNHCLTMTQYRQVTIATIPGTVHQVPYHFEDSRP
YYDLSPTVLSDAPPGR
>D0YVJ2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Photobacterium damselae subsp. damselae CIP 102761|TrEMBL
MVRKLIAAMLCCYSTLSYSGFDVVTLGAKGGIQDGNLTAFMLKSNSDDNYITLDAGSLVN
GLRAAVQKEAFNDLTVPPTCDYNEVGYLLNKKIKGYFISHGHLDHIAGLIISSPDDSSKT
IYALPSVHQTISQHYFNWKAWPNFTNQGEGYKLNKYVLTPLSTSGWQQVKGTELKVKTFP
LSHSGIESSAFLFENSAKEAVIYLGDTGPDSVENSQSLDTIWKQLAPYINARQLRGIFIE
SSFSNSTPDKALFGHLTPNWIQAELNKLASYTDNPQAIAGLNVVITHIKYSLKQGPDPKF
VIQRELNENNPLGINFIFTEQGDRIKL
>A0A086KKL3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii GAB2-2007-GAL-DOM2|TrEMBL
MHRLLDWDFHVLALPPASAVLVTRDLLTQFALKANMDIPGEILMAFSVAIYKNYRPNPYH
NFYHALNVTQVLCLLLALPDVAAQFSPIDYLVLSVAALGHDLGHPGANNLFMTRFDCWPS
RIYQNVSVLENYHAASLFQILRHPAFNVFCSVSPTNFAPIRKRIISAILWTDMAKHFDVV
AKLQAKIQGEMVLAEGIIVTLTKPYLEGLLLHAADISNPMMDFELCRDWAFRACDEFYQQ
NKMEEMGGFPPSMPSFEHFDEYNVAKCQVGFIDAICKPLFNSLALMFPAQLGDRATQLQK
NRCVPLIIFPT
>A0A086JKQ8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii GAB2-2007-GAL-DOM2|TrEMBL
MFDRRKHADFPKGQEGFLRFIIIPLYEEIAAVDTTDVVQTCCLQNAVANSERWRQLQSSP
EEFEAIDAKHQAIICVLKDRLEWRVQKNIAPTQRLLRASCAENQVRGSGVFFPTPECSGG
SGAPRASAPAEKRRESASASRDRDPGAADWKEETGNTAQALRERPPTEVAPQVDGEETCV
SDGVHERNRQDEGGGNEEGRRKAAGGETEKQGDDRKDLLHFESRLTH
>F2REN5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)|TrEMBL
MIVIAHVSDIHVDGEPRSVDRTRAVLRYLEELPYDLAAVLVTGDIADHGSPDEYAVVREL
LSSRHPLLVCPGNHDDRAAFRAGLLDPATGDDDRPGAPVNQLLRGEGFVVALCDSSVPGK
DEGFLEDETLEWLDGVLTGTPHEVPVLVAFHHPPVPLHTPYVDAVRQFGEERLAALADRH
PHLAAFLAGHAHTAAATTFAGRPLLVAPGVVSAIRLPWERPDTHPHVHLDLPPALAFHVL
DEDGRLTTHYRTVPV
>T2KKQ1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1)|TrEMBL
MKSTLYLLLFLISNMFYGQQAPAFQVVPLGVKGGVDETNLSSYLVAPIHTNDFVALDAGT
IHAGIEKSIENNIFNVSASEVLKRYIKGYFISHAHLDHVSGLIINSPADSSKTVYATQKC
MTMMQNHYFNGQTWANFGDEGPGFQIKRYHFETLNVKQEIPISNTDMHVTAFPLSHVNPF
ESTAFLVRHHNDYILYLGDTGPDAIENSQDLKHLWTTIAPLIKRNQLRAMFIEVSFPNEQ
ADTALFGHLTPNWFYKELSVLQKLTGDKALTGFKTIITHQKPPKENMVKIKAQLEKQNNL
GLDLIFPEQGVKLEF
>A0A2P9AMY1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mesorhizobium delmotii|TrEMBL
MDIVAHHFDAVALVISGDIADLADRDSYELFRDILAEFMLPPLPINVGNRDRRCVPGEVF
PGRLGPK
>Q4W442|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Equus caballus|TrEMBL
MGEVKAEEVEKFLDSNVGFAKQYYNLRYRAKVISDLLGAKEAAVDFSTYHAVSSVEESEI
IFDLLRDFQENLQAEKCIFNVMKKLCFLLQADRMSLFMYRARNGIAELATRLFNVHKDAV
LEDCLVMPDSEIVFPLDMGVVGHVAQSKKIVNVANTEEDEHFCDFVDTLTDYQTKNILAS
PIMNGKDVVAIIMAVNKVDGPHFTQKDEEILLKYLNFANLIMKVFHLSYLHNCETRRGQI
LLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKSHLVFDMDSVSSMS
SSFWAPLTFVFSCHYCSGSYPVYLTLVTQ
>A0A1M4ELV0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nonomuraea gerenzanensis|TrEMBL
MIVIAHLSDIHLGATPESVARTTAVMRYLDTIPGDLDAVLVTGDIADHGAREEYETAAKL
LSSRHPVLVGPGNHDVRREFRRSLLGEEPADGPVNQVLRTERAVYAMCDSSTPGRNEGHL
DDETIAWLKEVLDGTELPVFVAFHHPPVKLHGPPCDGIRMHETARLEALLAGRTNVPAVL
VGHAHTAAATGFAGRPLLVGGGVVSTLTLPWEGGTSFGNCVDFGLPPLIAFHVLDDEGRM
TTHYRAVIP
>A0A5C6DR99|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Novipirellula aureliae|TrEMBL
MSLHLIPASRRRFVQASLATAAVTLGCPWLMAATDESADQSADYWALLADTHIAANKDAV
SRGVNMFDNLNKIIDELLAEENKPLGVIINGDCARLRGRPGDYATLRIALDRITAAGLPI
HMTMGNHDDRDPFYAAFKKQKPDAALVDGKHVAIVPGRHANLFLVDSLNIVNEVSGKLGE
TQLQWLAKSLAEHRDKTAIVIGHHNPQFLPEGSTAEGSGLSDTAKFIDVLHSQPHVQAYF
YGHTHNWNRNKTSGGVHLINQPPCAYVFNAKHPNGWVRLKVQDESLAVELRALNKQHTQH
GESHTLEHRFAAVS
>A0A8D1K9I8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sus scrofa|TrEMBL
MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD
LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR
SEEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS
GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV
HYLLYKTGVANWTLEKEILNIVNSASLDSHEKKKATNNCHITFRSDPAILYNDRSVLENH
HLSAAYRLLQEDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE
AIEKPKALSLMLHTADISHPAKAWELHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS
TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNNISSSDAKR
STVKSSGSEGSAPINNSVIPVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKAR
LAAEEKQKEMEAKSQAEDGAAGKAEKKASGEAKTHPVNGTRTNKSDNPRGKNPKAEKSAG
EKQQNGDLKEGKNKTDKKDQSSVGNDSKKADDDYG
>A0A8D1E919|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sus scrofa|TrEMBL
MAQPRGNRGDTFSIDGYSFTIVANEAGDKTARPLARFSRSKSQNCLWNSLIDGLTGNVKE
KPRPTIVHDPRPPEEILADELPQLDSPEALVKTSFRLRSLVKQLERGEASVVDLKKNLEY
AATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRRSEEKPRF
KSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEASGDHALKF
IFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKT
GVAVSTDKNAEIALKMGWSSHRGSAEMNLTNIHEDAGSDPAILYNDRSVLENHHLSAAYR
LLQEDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPEAIEKPKA
LSLMLHTADISHPAKAWELHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKSTMVAQSQ
VGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNNISSSDAKRSTVKSSG
SEGSAPINNSVIPVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKARLAAEEKQ
KEMEAKSQAEDGAAGKAEKKASGEAKTHPVNGTRTNKSDNPRGKNPKAEKSAGEKQQNGD
LKEGKNKTDKKDQSSVGNDSKKADGKSITRIIFFRKVCSLMQAC
>A0A086KDW7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii p89|TrEMBL
MAAHSPYLGRPGTFSAPDECWNEERVPSGISPADTIREIVLFQALRNAERWSARAHVLET
KTGKTPAVSVSGFGSADASEGQRAIGSKRATPGKEDSTKSSKDSPRSAFASSPPHAHGPG
ASTPPGPQSVCGASFWTQRRLLVRHKTYSPARFGISAEDERDEGEDRLSRDEGETGALAG
SPGFALGKRDRMRERKLKPPRRRSWMTVTENRKRREQEEQRRDDRSRVKENVLRGILKRE
KEEKKSNEGTRDGVRSSTCRHANPEHRTNREDRKGKTSGNHEMDENADRSRMSGTRKPGN
ETWGREKDLEDHQPHTCEMLPQENEITDIAEETERGRAVESAGTLSQKQARETKKREASK
EKGKGARRHAGESMQTSQMSLETELLHVEKRVCETV
>A0A5C5VM41|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Blastopirellula retiformator|TrEMBL
MPTHQPIRLDRRAFLQGSSLLLTAAGSSLTFAADAQADLRIALITDLHHADKPAAGTRYY
RETLGKLREASDKFAGTPPDMVVELGDLIDAAGDVETELRYLSTINEPFQKISDDRHYVL
GNHCVDTLTKSEFLGAVGQQQSYYSFDRGDWHLVVLDACFTSADQPYQRKNFVWTDANIP
KKELTWLADDLAANDKPTIIFAHQRLDNAGNHMVRNAAEVRTILELSKNVQAVFQGHSHK
NDYQQIKGIHYCTLVAMVEGTGADSNGYSVLKLLADGSLHLQGFRKQAEYSWSRYA
>A0A0W0V7Z4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Legionella jordanis|TrEMBL
MITVPPTTLVQLSDIHYSGDNPLKGLNKLPAEGLQQVLKHLEENIPGDKTIILTGDLVDS
PEPAFYEELASIFKSLPHKVLTIPGNHDSLEMMEKHLFGHNIFSSFSLTTENWLILLCDT
NHPTQVEHAGRIISKDLQALEQALMAHPNQNALIFMHHPPVSFGAAWFKQIILENAAEFN
STIERFEQVKAIIFGHAHTEFSLLRQKKLYLGCPSTWIQFNHSLNEQLGFTAAPSAYMSY
RLYRDGSLLFQTHYCWP
>A0A0M6ZGF2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseibium album|TrEMBL
MKVEIDPGRNIEVLHITDTHLAPETAPSVPPKSLADAAAMLNGSTTDETFERILESVSDV
GFDLVLHTGDLLENADEAAYEKALDQLARLERPLLVSPGNHDDPEMLGAKLQQNGIERRC
IDAGNWRIVVLDSNLGDQGGLLGEAELLTLGGLAKEWDGHVLVGLHHPPLSTCADPDCTL
ADADAFLDVVNSAGNVRAVASGHLHSASEAERTGVKYLLGPSTCLQLVHEHPLPEHNRTP
TKGGLRRIQLLPTGEVHSTLHWI
>A0A177HWA1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces jeddahensis|TrEMBL
MARVLARVLELLQRSVPRRRRMPLRPQSVPAALARHVPAALLRHRRSRRPDPVGELVHVP
PPHPFGRALGLVAVVLLGAWLGLLVVGSVRAPVGPVDTRMALRPSLSGGTKINISPLGAL
ELRSHIAPIRLDVDVDRLDPVRAEALVRHPERLSGLQDEVTRDVGDGTRDLAVRSCVAVV
SGATALGLAVYRRPRRALAAGGLALTLLAASAGTALATWNPNSVLEPKFSGLLTSAPSAV
GNARSIVTEFDVYQKELARLVTNVTKLYDVTSTLPAYQPDPSTIRVLHVSDIHLNPASWH
IISSLVEQYEIDVIVDSGDTMDHGSAAENAFLDPIEDLGAPYVWVRGNHDSLTTQRYLED
MKNVHVLDEGRAVSVGGLRFAGTGDPQYTPDRSVKAQGDPAERMAGIRLASALRDQEAAG
TPVDIAVVHNPVAARETDGEVPLVLAGHVHHEEMEVMKLGTRLRIEGSTGGSGLRAVEGK
HPDPVQASVLYLDRDTKRLQAWDEIKLGGLGLTTAEVSRHLPEENQPGAPTTPTPSTASP
SKALPGTPSPGTPSTPRSSP
>A0A7R9D8M7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Timema poppense|TrEMBL
MLTLSTNLGWAHRFLFPPSPPISRRLADEDDELSEVQPDAVPPEVREWLASTFTRQLATT
RRKNDEKPKFRSVAHAIRAGIFVDRIYRRVSNTALMQFPPEVVKVLKTLDDWSFDVFALS
ESATSQPVKYLGYDLLNRYGMIHKFKVPPVTLETFLNKVEEGYCRHRNPYHNNLHAADVA
QTVHYMLCQTGLMNWLTDLEIFATLVAAIIHDYEHTGTTNNFHVMSGTDTALLYNDRAVL
ENHHISASFRVMREEECNILQNLSREEFREFRSLVIDMVLATDMSFHFQQLKNMRNLLSL
AEPSVDKSKALSLVLHCCDISHPAKRWDLHHRWTMQLLEEFFIQGDKERELGLPFSPLCD
RNNTLVAESQIGERFV
>A0A1E7XJ02|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lentilactobacillus sunkii|TrEMBL
MKLTIKDNQPFKICQLTDIHIGDFPLNAADQKTLNSLDKFLAAHSFDLIMITGDLIWGKL
ASNPVKSLGALFEVLNKYPIPVAITYGNHDAEGQFSRKDLRRIEERLKYPADKHHSQVVN
DRESYALEVYDGDALRHVLYVWDSGAYSHWPDDEQYAAIESEQINWFLQLPYNRDQDDLD
LGFLHIPFPEYNSAKLTILDGVQNEAVSSPETNSGLFYALKRQENVKAVFAGHDHDNNFV
GSLRNLQLIYGNVTGYNTYGALPRGAREIDITPDSINTNILLFDEINSL
>A0A177H7A1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodobacteraceae bacterium SB2|TrEMBL
MKFIHLTDTHVIGDALLYGQDSAARLRAAVASINAEHVDAGFVVLTGDMTHWGDAAAYAR
LKYEIKKLKMPVHLMVGNHDDTAAFGEAFPEIPRDENGFVQSGFDTPFGRFLLLDTKDPE
THAGAYCLARQAWLDRELDQTDGSIILFMHHPPFKTGIASMDRIMLHDAEKFYEVIAPHK
PRIRHLFFGHVHRAIFGNWRGMSYSCMRGLNHQVVLEMDGPADRIAGNFEPPAYGVVTLS
EDQVTVHLHDFADRSEQFFL
>A0A1Z5JW30|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Fistulifera solaris|TrEMBL
MLLDMDTFPWYHQLEQDILKVKYAVMSAFGQVERGIRSLEATRQVGHVLKEVTEILSLPT
FDAEAAARQEAFSPVTLDMKVMEQLEAYIHAIAALYRNNAFHNFEHVSHVTMSVTKLFSR
IVAPEVSGEDRTLHDHTYGITSDPLTQFAAAFAALIHDLDHQGVTNSTLIEENSPIAAVY
NNKSVAEPNSVNMAWSLLLDDSFTDLRNCIYTTPTEYNQFRQLIVNMVMATDIMDKSLSQ
ACKDRWVKAFSGGGDSSNEIREDLEQQINRKATIVLEHVIQASDVSHTMQHWHIYCKWNA
RLFEEMMVAYRQGRTQKNPADLWYEGEISFFDFYIIPLAKKLKECGVFGVSSDEYLNYAK
TNRKEWEAKGREVVAEMVARFGTLPVPTAYHLSS
>A0A0K0DKA7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Angiostrongylus cantonensis|TrEMBL
MVACSGSLCDTVVTTVDGRKFDIKDLDNDTWLAMVSEWSLPIFEIAEKHEDTLLSRITYA
VFKQADLFRIFKLSPIKFFNFFHALERGYWDIPYHNRVHAADVLHGCYYLTCHPVHPLIG
PSASPDSLLPPTLAQATPLSCSMSTLELMALYTAAAMHDYDHPGRTNAFLVAAEDKKVCD
EKYLVLEYILATDLKQHFEIIMTFNEKSNEMELMNESDRVLMAKMVIKMADINSPTKPYA
LHRQWTDRICEEFYEQGDEERRRGMPITPYMDRTDAQVAKLQDSFIAHVVSPLAVAMNEA
GLLPVLPGLVEPEMMINLKHNHQKWLQEIDKNTVEGGKK
>A0A517YDP1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Anatilimnocola aggregata|TrEMBL
MTFHILPADQPLASRRRFFAWAGLTAAVIAANRLPGEEIAKSATTRIALLSDTHISADKE
LLSRGVNMTDHLTQAWQQVNEAAGRLSSAIVHGDVAFLKGEMGDYGQVAQLLVPAGKSAV
PLHFLLGNHDDRANFRESLKSAAASPLESHHVSILELKQANWFMLDSLEKVNSTPGKLGT
AQLEWLAAALDAKADKPAIISVHHHPQKEGDKVAGIQDTKELFDILVPRKHVKILFYGHT
HAWGQKVQDGIHLVNLPPVAYVFAKEKPSGWVEAAVGDKGIELTLHGVGPANEAHGKKLE
LAWR
>A0A380UDL7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acinetobacter haemolyticus|TrEMBL
MTYQVSTSSQQDFVMIQITDTHLLEYPHLEFVGMQPEQSFHAVIDLMRQQHPQIDLIVHT
GDLAQTPTPVTYNRYIQHMQSLEIPFFHTPGNHDDVAHFPFHEVDQTQLTVIELGKWVII
LLNSAQPQRIDGKITESQLKQLHTLLLKLHDRYVILACHHHPFAMQSAWIDQHKLKNASD
LLETVKPFSNIKAIVCGHVHQDAIHQWQGIEFLSTPSTCIQFKPKSEKFALDEEHPGYRY
ICLKANGELETQVYRLKTSERMSSSEVLGYD
>B0SQY1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris)|TrEMBL
MKPNSLPPIILKNQDGGFYLSSSSELDDLYHFILGQAKRFVSAKSAAFYLRNERGNLSRI
GLISDKNNAGLIAKHVFKSKKSILVKKGTHLNPESAPASESYIACYLGDEIGDMSLGVLV
LEGIKHFQNFSEQDLDLINYFSANLNALFKDTVFSDKEPQFFNSLTTSVLLLIDNANIHN
NNNRLQYFLEEIIRVAVLINTSVDLEHVLVMVMESAKSVFRTEASSLLLLDEKKEYLVFH
TVTGEKREEVSKIKVPVGQGIAGTVAVTKQPMIINDAQNDDRVFRDVDKASNFITRNILA
SPLIVGDEVIGVIEAINTIDRNNFSQDDIDTFLSFSSACAVAIQKTRLLDNLNVTNLELK
QKLSTLESIFDLGQAVLESHDELGLMSKTLSILTKELSCEDAGMVIIEEKNKNRIQVYAR
QLGIVRESFFPMFESRLFLSLMESGNPRMAVVTPQLEESFLELEFYTLKKNFLILPIAPR
GGNLRAALYVSGKHSAHSFNETDLRMLKTLSSPLAKAYENLRLNQEIITKKSIEKEIEIT
RKIQNNILPNGLIQSPLFDLGVMSVAAKEVSGDFYDFHAFGDEQFSFLVADVSGKSLPAA
IFMAMSSSIIRTLSRTTDLSPSELLFRANQLIYEDSQSGMFVTLFLVNYQRKTRTLKFAS
AGHNDQIWIRGDGSYELLKGKGAPLGVVPHTNYQGGEIQLEPGDILVFYTDGAIEEKSPD
GEEYGLDRFIEFIIQRRDAASQDIVEAVYDDIRSFSNSEEQYDDFTVMVLKFAEVTSFEM
VKSFDASPNEIPKLRDFISEHLESKITKPFAFDDILISLDEAATNIVMHSYKDTEILNPK
FECKFELIGDKLKIVLVDEGKPFDRKKVPKPSVEANLKGERKGGFGVYLMETLMDKVSYE
YNGKQNITYLEKTIV
>A0A483A085|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bathymodiolus heckerae thiotrophic gill symbiont|TrEMBL
MKHFIQISDCHIDDTAQSLGVDSQKNLATVVNKITTLPSDALLISGDLTHNGALQSYKIL
KKILSPIQTDIFVIEGNHDNFEPLNAEFSSCLFTQFTLGLWDIISINSVQIGKTSGFVSQ
HALAKLDQQLSHSSAKYSLVVLHHPIVSMNSTWDDTLSLENPDDLFALLKRHPKIQAVLF
GHAHESAEFNKNGIKIIACPSTAVQFNHESRIGFNHYTLLDDGQLHYTTQWI
>A0A063Y3S4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nitrincola lacisaponensis|TrEMBL
MTPVTLLQLSDCHLTPQAGQLFRGVDPRQTLAQVIRHVQQSGHQFDHLLLSGDLVHHGDA
GVYQELLQQLAVLELPTTWLAGNHDDLQVMQQAADLDRFSVSLGPWQLLCLDSNHAPDGR
GSGAIASHTLERLSRQLAADRRFTLLALHHNPLASGTEWQDQIMLSNASELWQCLAQAPH
CKAIICGHLHQPLHWQHQGVSVWSAPSTAVQFCPGSAQVEVAQQPPESWPGYRWYQLWPD
GRIDAHFESVPLRTADQGEPCPNRC
>A0A5C6C0Q0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Novipirellula galeiformis|TrEMBL
MPIHLDSQSRRRFLQNLSATSAAVALSTTLRADESTTAMDDRFFALLSDTHISASPDGTA
RGINMTDNLKSVISDIAGLEKRPANLIINGDCALSVGSPGEYQNFANCVAPLDELGIHLH
LTMGNHDDRETLYEHFAKARPTAQPVPVKHVGVLEGEFANWFLIDTLIRPGHVAGEVGYE
QMIWLTKELDARPDKPAIVMGHHTLQFTPPKPGARWTGLWDTDALVEALQARPHVRALFY
GHSHVWKTETIGNLQLINLPAVSYVFSEEIANGWVSAHLDEHGMKLQFHTMDPKHPQNGT
PLEVVWG
>A0A093BPW1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Tauraco erythrolophus|TrEMBL
LSHRLRCLVKQLEKGDINVVDLKKNIEYAASVLEAVYIDETRKLLDTEDELSDIQSDSVP
LEVRDWLASTFTREMGIVKRRPEEKPKFRSIVHAVQAGIFVERMYRRTSSMVGLAYPAEV
IVTFKEVDKWSFDVFALNEASGEHSLKFMMYELFTRYDLLSRFKIPVPNLISFAEALEIG
YSKYKNPYHNLIHAADVTQTVHYIMIHTGIMHWLTELEILAMIFAAAVHDYEHTGTTNNF
HIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILANLTKDDWR
>A0A223UHM4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella quasivariicola|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFID
SSHAGTSKGWLTDETIGWLEAQLFNGGDKPATVFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGDQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A2K8L0K6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mariprofundus aestuarium|TrEMBL
MRLKVLGCYGGQLLGFRLTSFLVNDSILLDAGSPTEALSLEEQHGIRHICLSHTHLDHIK
DIAFLADNRSLKRLGGIKANRTINVHSLPENNETLLRDFFNDHIWPDFTVIPSKKDAILR
LHDIKAEVPFEVDGVRITAIEVNHPVPCTGFLIEFEGKQLIYTADTGNTDRIWEIANEQP
NLKAVIMDCSFPNSYQHLADISGHLTPNGLKQELQKFEAVGRVPVYLYHMKPETLNVISA
EVEALNIPLLRMLTQVDEFLF
>A0A378Z046|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pandoraea pulmonicola|TrEMBL
MLLCQITDLHVTRPNALACGRVDTARALRHAIAAIHRLSPRPDAVIATGDLVDTPYRSEY
EVLRESLADLSIPLYLVVGNHDHREWLREAFPDHAYLHTGSEFVQYRVDLGPMTVLVVDT
QNPPSPGGHLCETRLAWLDEQLRACAGRPTVVAMHHPPFDTGIQWMDGMGLSAAGREGFG
RVMSRHRHVERVICGHLHRSIHASVQGAPGIMASTCVSTAHQIALDLSAHAAEWIMLEPP
GFALHLWQPGAGLRTHLAYVGPYDGPYTFEGESVS
>A0A2K6EJM5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Propithecus coquereli|TrEMBL
MDKKEKNILCFNFLFQRCKGKPKVLKSKTQNKVKTIIQRLLDTDDELCDIQSDAVPSEVR
DWLASTFTRKMGMTKKKPEEKPKFRSIVHAVQAGIFVERMYRKSFHLVGLAYPAAVIVTL
KDIDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLIAFAEALEVGYSKY
KNPYHNLIHAADVTQTVHYIMLHTGIMDLRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPE
GIDRAKTMSLILHAADISHPAKTWKLHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKS
TMVAQSQIGFIDFIVEPTFSLLTDSTEKIVIPLIEEASKAETSPYVASSSTTIVGLHTAD
VLRRSSAKGSTNDGSFFPDYSLAAVDLKSFKNNLVDIIQQNKERWKELASQEARTSKKRK
CIHQ
>A0A1C5UAG0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Clostridium sp|TrEMBL
MNFAHLSDTHVLDKRSQTNQLLELVDDGKKLAQTITAAVNHPQKPELLLITGDLVHEGTA
EDYAYFKSILEDNCKGIPYVVCLGNHDRRQAFWEGFMGEKGVAKPYVETTMINGLRIIAL
DTSPVDGNEIGEMPQDQLDYLAEELKTAAPKGTIVILHHPPQGFVLKGFEGLCPVRDAFA
GIVEGTDVKAVLSGHTHYLSCHSKNGVTYATAASTAFSMDNAKKGDLDFIDACSYNLGRI
TEDSVYVGTETVNYQYKTLFTMKAADMEKMLKNQK
>A0A1S8TE89|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium puniceum|TrEMBL
MKKFRRISVAIAIILVGVIAAIYMNKPKAVDNSTESAISNEKVTSTDESTENTIPKKDLT
FAVLGDVHGNLPSFQDAIEDLHNINPRMDLLVLNGDTVDQGKEESYVSIKDAISKNKNLL
PKTIIKNIGNHEFYDYEAGSNSPEQVKTFINRYLEFAGEEKVYHDKWINDYHFISLGSED
GNSKTTDSVRAFISDIQQKWLKEKLSENYQKGKPIFVFLHQHLNDGNTGWIGVEQSKEVR
KILSKYPEVILFTSHTHSDLNNSSILFKQPFTMIHTGAVSYTIVYDDKSDGGRRREPYIK
GLYVEVDGNKVVVNGRDIKEKKWIFNKEISMQ
>A0A5P9JPQ5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. THAF7b|TrEMBL
MPGAPLTAVEDSVLLVQLTDSHLFAEADGKLLGMNTCDSLKRVVELAIEEQPRIDLILAT
GDLSQDGSVASYQRFRQLAGRIEAPARWCPGNHDDLGAMREATRGSELMEPVLEIGGWRV
VMLDTLVAGSVYGMLRGDQLELLDRALGEAPERHHLVCLHHHPVSIGSRWMDSIGLRNPE
ALFEVLDRHDNVRALLWGHIHQAFDQSRNGVRLLATPSTGVQFTPQSEDFQVDSAAPGYR
WLRLYADGRLETAVSRVSGIAFEVDYSVKGY
>B0EMM7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Entamoeba dispar (strain ATCC PRA-260 / SAW760)|TrEMBL
MLTQRHLQVNFYDRANSFIDGLNSNRIDLQIQALRNIEIEFLEYEDDAAEKSWLYSFIKY
EKKAPKSNHSHRIATKKELINFLEYTSKIIINLVVACPHEELLRHSIPIIIRLCQNKLLP
NDFFKKLYQNAERLSGPIVMRAQDLILRLFNKLSSEEKKYFKLLAISGSENSQIESLHFL
CKLITAHEISIEVVQKLIKQICKNIQQLESDVFPIIQIPELRTLLRKSLLTEYLTNFQDT
GVLSALKIIAETDPFESDVDDIKQLLDMSILNETENLKDVLINLAQKNENLFSSCLLGMV
RLEGFNETTKWLTGEMITDHIEDLMKTLLNYNQLPEASSSIVRNTFIQYNVLITKGIRTN
SNNHIIFVDYNSLIGKEILWDVFLKKKNQKIEHLLMKIYQGKLKEYVIDALHAFMKNPQL
IAAEIIEKSLKDLKQSLKENKEGKIKLKQFIKLKCGIPVGQIKVKSTSYLCQSSEDIKQL
KYLSEEVNNKIKQTKEKLETKIEIKEKEYLPETPVDAIVTDILASVYEQKGTSAEWIKRV
IKNNKYFITTQINNEDVSINDMVGDLLKKDGSIFLYIQEGVKTLNCQKLTKSKSNDKIIN
CDPKTLKQLSFIIEENEIKNVIELIQKKEMYSIGITLLKEINPFIKWRLSPIENCKEQTG
YEFIGFERLMTQNEIQEDDFKELISMFCHSIETRKGNEKYIAEILLHFEKLAKKELWYIN
EEQIKKIQKRYFMEGNERIINTICDILLLRNNQIIEWNKEVVVEPIKRVVKELMNQELFE
TLIPYLEEPSELVEECYEIIIQYIDIKYNINDLFIQKMIENITNRGKGFKFSIRAMKLMK
DKQKLLQPYLITFIDSLFPKGKLTEIKEDTLHDYIEMICESCKTCNEEQKKEICHHFDMI
LSMLESNGNHIETRKGLWCGLTNQGSTCYMNSILQQLLHTKMFCNKLLEKKVITPKYFED
TEENKNQKNLNIISIEKFDVNKTKTIVNKVQILKKENGAINDNIENDSKEVMQKIEQSDN
TISKTQEEIEQEINSQKENIQNKEQNEFITHNKNEFKDYRMIEGLQKLFVEMKESKLQTV
NTKEFCKEAHGSCYEEINVYEQMDAQEFFNTIISTLEICKKEKNIIEARKIFTGETEISI
KSQCGHIVKRNEEFCSCALEVEHYQSIGQSLKALCEGCVLCDYRCEQCGLKSDAQRSEKY
KKLPETLVFHLKRFGYNEQFQIVKYNGKFEYPNEIDMKQYCCKEYKGITKYKLVGIVIHT
GSAYGGHYFSNILLNGQWISFNDKLVENIGNGNWFGGEVSNAYMLFYQQINILEEKENET
FMIDELLLKRIEKMNYSYVLSKQASKPFVIDFIKGINESCKYIGNTLSFIRTIILKRNPE
QSLGIFEGISQIMNQEIAREVLQKISTYYLKDYLIWGKSMIISAIKQIQEPVFNELIIKE
VENGNSHGIEVIQELYKLMQVKLSTCVRLSVHIIKNQKYNYVQGKIACSFILEGIQQKIY
QFDKDILLSFKSTNSPESLIQEIIEKYPTQKVNECALKLIKSSLNKREINDEEMIKLKRL
VCNVNCAVCIVNECLKHLCMAPDSCRYFKIILITMQIVLLSPLIYNELKKKIKEFNENLD
FYSLKIVLIE
>A0A7X0J3Y2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pedobacter cryoconitis|TrEMBL
MKKKIYFLLLLLSGFSISYAQQTRENSFKVIPLGVKGGLDESNLSSYMIAPAGSNNFICA
DAGTIRHGLDVAIKNQLFKGPADEVLKNNIKGYLVSHAHLDHVAGLIMNSPDDSAKNIYA
LPSVIEVLRAQYFTWKAWANFANEGEAPRLNKYTYVHLEEKVKIDLKGTEMQVVPFILSH
GPAYESTAFLISHQDAALLYLGDTGADEIEKNTQLEKLWKEIAPLIVKNQLKAIFIETSF
SNKQPESQLFGHLTPKLLMTELTKLSKLTGISALQKVSVVITHMKAWDKEELYLVNELKK
TNTMGLKLVFPEQGKALMF
>A0A7Y7H197|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mucilaginibacter sp. SG538B|TrEMBL
MNLKYKLLPFLYIFLFPVILVAQTPKVSTFRLVPLGVLGGIDESNLSAYMLAPKGSNNYI
CLDAGTIHYGIEKAVRCKSFKVPANTVLRQYIKGYFISHSHLDHIAGLIINSPEDSTKSI
YALNDCIETIKTHYFTWKSWANFADQGETPALKKYHYKVLEPGTETAIENTELKVRAFPL
SHSNLTSTAFLVNSNNNYLLYLGDTGPDEIEKSSNMQNLWQAAAPLIKSKKLKAILIEVS
FPNEQPDKTLFGHLTPKWLMAEMDKLASFTGTDAIKGLNIVITHLKPPMTSISKIKTQLK
AANKLQLNLVYPQQGKALNF
>A0A4W4HJP2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Electrophorus electricus|TrEMBL
MNDMQIGQWSVAGQLKCMIRDIDESNVDYEQFKKNLEYTASLLEALYRDETRQSLDMEDQ
LQELRPDSVPKEVHNWLASTFMQQARRPLRYPDYKPSFRSIVHAVQAGIFHDLLTLFTEL
MIRYELNSRFKVPISCLMSFLCELEQGYNKHNNPYHCQTHAADVTQTLHCLLLRTGLVHW
LTELEVLASLFAAAIHDNEHTGNTNSFHILTRSDLAITYNDRSVQESHHLSSTFCILQNE
QMNIFTNLSREEWVELRSLVIEMVLATDMSFHILQVKAMKHSLQQQERVDKAKALSFLLH
TADISHPAKPWVLHSRWSKALTDELFRQGDKEGELGLTISPLCDRNTAPVAQSQIGFIDF
IVDPTFSLLMDMAEKIIIPLVQDNPEPPEPINRHRENYLLKIIKYLVQQFIIKLQTSNTS
GQQRYDGSPDHCKNLLSQFSMYSPPPXXXXXXXXXXSLRRHGNRVITVDRRGRGMGNRSL
GQPGPSIAV
>H3RG27|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pantoea stewartii subsp. stewartii DC283|TrEMBL
MSANPTLIAQISDLHIKAQERLSYKKVDTHTALLRAIATLNALQPRPDVVVITGDLVDFG
TAAEYQTLREALEGLERPFYLMAGNHDDRQALRAAFPDHTYLQQGPTLNWRLIVRDVQLL
ALDSSVPHQPWGELDDRQLRWLDDALTASPDMPTLVMLHHPPFVCGIDHMDRQRLRQPEA
LAAIIARHPQVERVLCGHVHRAVQTRFAGTLACIAPGVSHQVALDLQPDGPANFVLEPAG
FLLHRWQREQGMTTHQCAIGDYDGPWPFYDENGLID
>A0A2G4AUZ3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio splendidus|TrEMBL
MNTVYQISDCHLSDESSYENLRRALEYVSKDTACKTIFLTGDICCNPKSGDYIRLEAFIR
QHISDQSIYAIAGNHDDSRLMRTELKGSSIFVTDKATSCGREFVFLDSSFKPLDKRHPLG
SGRIDNLGMARLKQQLRKTKNPIVVIHHPVIPVGADWMKAIRLENDVDVMNVLRKYRVRD
VICGHGHDGITATQQGVTQYMAPSTAYGFDHSINEYNRSEKIGLSRISFSADSIDYQAVY
F
>A0A484SJI4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|plant metagenome|TrEMBL
MKFIHLTDTHLVADGGELYGTNPKQRLRQAIAHLLARQPDAEAVVVTGDLTHHGHAQAYA
HLRECLSALTLPVYPILGNHDSRVVFKEYFPGVAQDEHGFIQYSVDFGSHLALFLDTNEP
GVHWGVYCETRAAWLRARLAETDRPVLLFMHHPFFPIGIPSMDFLSLRDPAPLLAAIAGH
EARIRHVFFGHIHRPICGQYRGMGYSTLRGTNHQVALDLHGSAQCIIGSHEQPQYAVVQV
DAEQLLIHVEDYLDCDRQFLLHEMRDGAAGLK
>A0A484SSM1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|plant metagenome|TrEMBL
MLIAQISDLHIRLPGQKAYRVVETDAYLPPVVDALNRLDPRPDCVVITGDLTDFGRPAEY
AHLRHLLAPLQLPFFLLPGNHDDRQALADAFPEHAYLRTDGPFVQYAVEQYPVRILALDT
VVPFKGHGALCAERLQWLETELAREPGRPTLIAMHHPPFKTGIAHMDAIGLLSGAPELEA
LVGRHPNIERIICGHLHRTIYARFGGTVASCCPGTAHQIALDLRPAGPSAFVMEPPGYQL
HTWQGGALTTHSAVLGEFPGPYPFHEEGALIDE
>A0A377WSX1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDAQNMRYVVDDFATRLLFID
SSHAGTSKGWLTDETISWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A0N4UFH0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Dracunculus medinensis|TrEMBL
MLAMGCCDCLTHFALHHPNRQRKRSVVDAFKDKRYINFDGKRRISADVKNALADDHEWTF
NVLHLERITENHALSQLGIKIFERWKVQETLRCSDDIIVRWFNTMEAHYHNVNPYHNATH
AADVLQATSYFLDSPTVAKNVEDIHATAALIAASIHDLDHPGRGNAFLINTRQPLALIYN
DQSVLENHHVALAFQLSLQPSNNVNIFARLTRDEFIALRQAVVDMVLATDMSRHFEYLTK
FQQTVDTLQQLLKNCDEPRNSVSISICRMMIKCADIGNPTREWSLCYKWAMRIVEEYFDQ
TKEETEKGLPLTMALFDRNTCNVPLTQCGFIDMFARETFTSWSEFAQLPEILTQLEKNYE
RWKRQTIEWNPANNHNLLSET
>A8JAU0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chlamydomonas reinhardtii|TrEMBL
WNFNAFELYTRTHGNPLVTITVTLLESYELLDGWLLDRQKVVNFLLRVESEYNPNSYHNN
THAADVTQTSCVILESFKKQVKQISKLEYFSIIIASAVHDLGHLGVNNDFLINSRHPRAT
MYNDKSVNENFHIARAFAIARESPDLDIFSGFSLDDQKQIRKLMIETVLSTDMAVHFDLL
SRFTSQVDAKPDLSEWTDRTLLYQMLVHLADIANPSRPFHLARGWAERVIEEFCDQGDRE
AACGLPVSAMCNRVTMNMPRAQLGFIN
>A0A853SEU4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Janthinobacterium lividum|TrEMBL
MRYDRGPLTAVRLAAPPAMRLLILSDLHLEVWGEDTPAIDLAACRPDVVILAGDIDTGSN
AIAWAARTFGSLPVLYVHGNHEGYGHQLEHMQDAVRDACASANAQGAGIRLLDGDAVVLN
GVRFLGVTLWTDFLLFGAERRDEALNAAQSYMPDYKRISTGGDTPRLLCAADTAQLHAQH
RAWLEQQLAQPFDGKTVVITHMAPSMLSVEEQYATNLGSPAFASQLDALVAQADLWVHGH
MHASLDYRVQQCRVVCNPCGYKRPDGTPENERYDSGFIIDLSSAV
>A0A0M2HQD2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium hydrocarbonoxydans|TrEMBL
MSESPQSVYAFGRHEPASHVIIHVSDTHFLAGGARLGGRYDVDETFSRTLEAIMAVHPHP
SAIVITGDLADLGEPDAYRRLREAVEPVAAALDTAVVWVAGNHDERPALRAGLLDLEPSE
EPVTSMWDLDGLRLIALDTSVPGWHHGDIDERQLDWLAGVLAEPAPHGTLLAMHHPPLPS
HLPLFDILELRHQDELADVIRGTDVRGILAGHLHYSSHGMFAGVPVSVASATCYTMNVAR
PAPDVNGMDAAQAFQLVHVHPDTITHTVVPVLDAPTGDFFSQEWLERMARLTPEQRLEAF
SRKPGR
>C1B8E1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodococcus opacus (strain B4)|TrEMBL
MSQYGEPDHYILHVSDTHFVTDGDLLHDRVDSDANLTRLFDRLEKTGQRPEAIVFTGDLA
DMGEPEAYVRLRRIVEPAAERLGAKVIWVMGNHDARPAFRSGLLDAEPTQDSVDAVVDVN
GLRIIVLDSTVPGFHHGLISDEQLAWLTDVLAEPAPHGTLLALHHPPVPGLLDAMGSVEL
QDQHRLETVLAGTDVRGILAGHLHFSTTCTFAGIPVSVASATCYTQDLLVGSGSIRGQDG
AQGYNMVHVYRDRVLHTVVPLDVSPTVYEMTADEIRQSIEQLTAPGV
>A0A486XW20|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rheinheimera sp. BAL341|TrEMBL
MSLHLIQISDPHLFSDAAGCLLGMNTLHSLHCVTDVIHQHHQQIDYLLVSGDLSQDGSVA
SYQHLQHALERFNCKVLWFEGNHDNPASMQQVTVAAGYLQRVVRAGNWQLILLNSQVEGA
VFGHLDQSQLQLLEQALQQQPQLHTLISLHHHPLPMGSAWLDHIGLQNSAEFNAIVQRHP
QVRCVLWGHVHQESDKTIGGVRYLSSPSSCIQFKPGSSHFALDNQAPGYRWLTLHDDGSI
DTGVRRVSGIKFNVDMSGTGY
>A0A2N9LKE5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Burkholderiales bacterium|TrEMBL
MKTYIVGGWVRDRLLEQAGRKPAHSADRDWVVVGSSPEEMLAKGFTAVGRDFPVFLHPQT
GEEYALARTERKTAPGYRGFVVHADPAVSLEQDLQRRDLTINAMALDEHGQLIDPHHGQA
DLQQRVLRHVGPAFVEDPVRILRLARFAARLPDFSIAPQTMVLARGMVAAGEADALVPER
VWQEITRGLMEDRPARMLEVLADTGLLARLAPELTVPAPLRAALDRVAQLGAPLAVRFAL
LASGASSAAGQRALLERWRADNDCSQLARLLFELRAELRVAPTPAELASVLERADALRRA
ERFAQLLTAFEALEGGSADRWRAAAVAASAVDAGAIAARVGPDPAAISQAVAAARRKAIA
AATAGGGDPRA
>A0A7U2JEU7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALHERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFID
SSHAGTSKGWLTDETIGWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAYYAGPWLYDENISCPTEER
>A1KAT9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Azoarcus sp. (strain BH72)|TrEMBL
MDDDILIDCGTGVGDLEYGQLKRIDHIFITHAHLDHIAMIPLLIDSVGEARGVPVTVYGS
AETIRILRSHIFNWLIWPDFSAIPDRHRPFLRFQVIKVGETVRLARGAVTVMPAHHTVPA
VAYCLDSGDGQLVYSGDTAYCPELIAAINRTPHLRHLIVETAFPNEQQGLALASRHLCPA
MLGAMLDEITVTPEVHISHLKPGVDDRIMDQLSSYRGPLRPRRLMHGQELTF
>A0A086M4N1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii RUB|TrEMBL
MKVSPHRTSERGSSPTGGESGKHRFTQSGALRRQSAAPGGAKRSTMTGFLKAEPNPGSET
QDLEATQRRLKSAHRRTMLPTWILTGLSLAYVLFEGGRLLYETTLQQWSEEAILHIDKEI
FFLHDFAAGFYSLAEQLTSDYCFLNFMNAHSPPAAPTSTREEVQNLISGYAPSFCSWIKD
LYFFEEPLADTADRSTYQLLNTTYICGERFADLVQRINGNMVEVVQNYTLVKMRLIEMLA
PLVDNRNWSPHLLCDLDFSAGDLWACHDGLTALEQLRGQLSGYLGREWHLYSPILSIVIV
FILATLFFSRRHAFNAVFHTRFESLWAMLQQIDQVRKQ
>A0A0L0M6U5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Burkholderia verschuerenii|TrEMBL
MGSRVIVRGEIPTAPVPPATKTVQTPAAAECTFSEQSLTGFRWVAPRRAACIRRNHGVNR
QGSDGCPSPETKLMLLAQISDLHITAPGTLAYGRVDTAAFLTRAIDALNALAPRPDAVLI
TGDLVDAGGIDEYRQLRTLLERLAVPWFPLLGNHDDRANFRAVFGDRAGAASDGFAQHAF
DVGDMRVIALDTLDPGSGAGRLCAARLAWLEAQLDACRDRPVIVGMHHPPFACGIGFMDA
IRLAPDDARALDALLRRHPNVERIVCGHVHRPITARFGGTVVWCAPSTAHQVALQLTPDG
PDALVMEPPAFGLHLWRAETGLVTHCRCVDQGDGPYVF
>A0A0W0WBS8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Legionella maceachernii|TrEMBL
MFNDFSTKDSLKILQITDTHLFAHHSSLFGVNPNKNFDEVMKVIFRNELEDTDFILLTGD
LSQDETSAAYQHLLKSFKNCKSRVFWLPGNHDNESVMSAVFNSFSLFTRTRLLELKHWNL
VFIHSKLEGSGSGYIHLDELNEVEKIINASKKNIALIMHHHPIPVNTPLIDQYILNNRED
LWKTISNSKVKLIVTGHVHGDYSFVYQGVNVECSPATVFQIKKGTDTLQIEHSIGYKIHY
FDKDRYRSKAVIWEGTA
>A0A7D7X0F6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio spartinae|TrEMBL
MLIAQLTDLHIKQSGKLAYQKVDTLGCLRRAIDHINHLNPMPDRVIITGDLADFGHPSEY
QLLVSELQRLKPLVRVVPGNHDNRTHLRDALQGWLAFDTPECCNFSEPLGGYQLIGLDTA
VPGQPYGMLSQASLQWLDEQLSAVTPHPALLFMHHPPMTVGLHHMDVQNLQNSDALYDVL
RSHPHVAGIVVGHVHRPIVATWHRIPVWIGPSHSHAVTLDLDPQAPACFSLEPRAIQLFR
LEPSGICSHISYIDAVDGPYPFFDDNHRLID
>A0A448GTL2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moraxella cuniculi|TrEMBL
MKPHQSAKQPTHQQMTLVQLSDLHLTGSIGKSPSYQSTLQALEVIVKLQPQLILLTGDLV
NDGNSDAYNWLFLQLKNTGIAHFAIAGNHDVTHEIGTGLPYHQRLHLPLTADTRLLDCHR
LAFDGINWQILLLNSSLAGCTHGALSQDTLAWLQSSLAQHPMPAIIALHHHPQAVGSAWI
DAYMLSNHRAFWQIIEQHPHVHTIVCGHVHQVHQLHPLKNHRVQLLSCPSTDRQFLPFAH
DFAIDKTASAGFRVIHIDNTSRLVSYIKSLDN
>A0A379ACP7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Enterobacter agglomerans|TrEMBL
MSVQPTVIAQISDLHIKAFGRLSYKQVDTHAALLQVIDTLNALQPRPDVVVITGDLVDFG
RPEEYQTLREALQRLQLPFYLMAGNHDDREALRAAFPDHTYLQAGPTLNWQLSVGGVRLL
ALDSSVPQQPWGEVDEQQLQWLDQALREAADQPTLVMLHHPPFACGIAHMDRQRLRHPEA
LEAIIVRHPQVERVLCGHLHRSLQTRFAGTLACVAPRRVASGGSGSASGGAGSLYSGAAR
LFAPLLAASAGEWSRISARLATFRDPGHFTIVRG
>A0A212LBA4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Desulfovibrio sp|TrEMBL
MRILQLSDTHLRGDNKLSFRVVDTRRCLDATVAHLKSMAQKPDVIILSGDLADSGDLNAY
HILTELFSPLNIPIYALPGNHDRRDRMQNVLKDWCPSDPDVAPHICYTVEMDDLRLVVLD
STHPGSHSGHFFPAVETWLTGELRKRPQVQTLLFMHHPPFTTGLGVMDEPFENQQLFAAL
VADNPQLRLCFGHMHRPIITQWQGRLCVTAPSAAMQIDLDLSPEGGDTFVMEAPGYLLHH
WENQTLNTHVCQIPTNVTFDGPYPFADSVNPVGPSD
>A0A2P9I5N4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Actinomadura parvosata subsp. kistnae|TrEMBL
MIVIAHVSDIHIGATPESVARATAVMRYLDALPGDLDAVLVTGDIADHGEREEYEEAAKV
LAARHPVLVGPGNHDVRREFRRSLLGEEPADGPINQVLRTGRAVYAMCDSSIPGRSEGEL
TEETLTWLEGVLDGTDLPVFVAFHHPPVLLHGPVDQIGLRAPERLESLLAGRAQVPAVLT
GHAHTAAAATFAGRPLLVGGGVVSTLKLPWEGGTSLDNCADYALPPLIAFHVFDDEGRVT
THFRAVPV
>A0A119A2C1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. TAD18|TrEMBL
MPSVSTLTTDAPVLLVQLSDSHLFADADGSLLGLKTAQSLQQVIALVRAEQPSIDVLLAT
GDLAQDGSVAAYQQFRQATQPLAAVARWLPGNHDNVQHMAAAAVQSRLMEPRVDIGNWRI
TLLHSNVANKSYGYLEDNQLQLLAQSLSEAPDRHHMVCLHHHPVAVGCEWIEPIGLLNAE
AFWAVIDRFPQVKAVLWGHVHQPFDQQRNGLRLLATPSTCFQFAPHSADFNVSNEAPGYR
WLRLQPDGTLQTGVSRVAHFDFEPDYGAGKY
>A0A5Q9LKX5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella quasipneumoniae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QMARQILGSLNYPLYLIPGNHDDKVHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFID
SSRAGTSRGWLTDETIGWLEAQLFEGGDKPATVFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A1J5R3G2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|mine drainage metagenome|TrEMBL
MILCQISDLHIKRKGALAYGRVDTAGFLARCLERIRALHPLPDAVIITGDLVDWGDAEEY
AHLRELLAALPMPHYLLVGNHDSRQALRAAFPEHAYLGSADGFVQYTADLGPCRLVTLDT
QDPPHSGGRLCEARLRWLEQELERADRQPVILAMHHPPFVTGIGHMDAIGLPAADCARLG
AVVARHPNIERVLCGHLHRPIQHRFAGTLASTCPSPAHQVALDIRPDAPAAYRMEPPAFQ
IHAWLPGAGLVSHLVPVDESPGPYPFFHQDGQLID
>A0A238K753|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Maliponia aquimaris|TrEMBL
MARFLQLSDLHLVVPGARVSGRLDTPALMRAAVDRLLARLPAIGPIDAVIVTGDVSDDGS
AASYATARAELDRLGLPLLAVPGNHDARAAFRACFADLPFMPEAGLIDWVQDLGDTRVIG
LDTLIEGQGGGVLRPESLELLGRALDTAGDRAVLVALHHPPLRTGIRFMDAIGLDNPGAL
ARCLERARAPLRVIAGHVHGVFHGQLGPHAVCTAPALCSAFALDRRAEAPVGFMSGPTGC
AVVDTAPGGVWAALPLEHGEGPFRF
>A0A238K5N1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Maliponia aquimaris|TrEMBL
MKFIHMSDIHLAAPGKLVDGIDPAPRLAQALAHIARHHADAARLIITGDLTHWAEPEAYA
ALKVALKGMPVPVRLMVGNHDTREGFLATFPDHPRDDAGHIQHAEDLPEGRFIYCDTIQP
ETHAGHFCEPRRAWLAKQLAGTQRAFVFFHHNVLHLGDPATDLLSLNDADQAPLRALLVA
NRDRIAHIFFGHVHEPLSGTLAGIPFSGVTSTVHQTIPNLSPSLMSGMGPLEPSYRVVLI
RGEDVVIHQIPFAWEGEVIWHGGSWQDWVEKA
>A0A7M4DJH9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Occultella aeris|TrEMBL
MSFNSRFDGCTTLGTVTSSLPLRAAEYPHPNHVLVHLSDTHLLPEGELLHGVAPMRDHLE
ALLADLEATNMRPEALIFTGDLADRGEEEAYRILRGIVAPVAERLGAELIWVMGNHDDRA
TMRRTLLDAPADGSDADLTEPYDRVVMLGGLRIVVLDSTVPGRHYGEITPAQLEWLAGVL
AEPAPEGTVLALHHPPAPCVMDLLVTFELRDQDALAAVLTGTDVRAILAGHYHYSSTSTF
AGIPVSVASATCYTQDLQTPDRGTRGRDGAQAFNLVHVYADTILHSVVPMGGGATVGAHV
DANATAERLAAAGMYIRDAQVLHEVR
>A0A0F7KVS7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Croceibacterium atlanticum|TrEMBL
MTRSARLFHISDLHFGLEDRRALDWVRQEIAEKKPDAVAITGDLTMRARNREFTAACEWI
RSLDVPVTVEVGNHDMPYFNLIERFFSPYKRFRAIKNLVEAEIDLPDIAIVPLKTAVSAQ
PRFNWSKGWVTDSALQRCLQAIDALPEGTQALVAVHHPLREVGTQGTALTRNGQKALTEL
AKRPVIAVLSGHVHDAFDLVQGTRHGPMRMIGAGTLSQRLRSTPPSFNELHWDGAKLDVR
VRNLEHVSTADMMIDDVPEDALPPREPGEPVAPVHRIPEVDPPVH
>A0A379J008|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas mendocina|TrEMBL
MPSLPTPPSDSSVLLVQLSDSHLFADADGKLLGMDTCDSLQRVIQQVLEEQPQIDLILAT
GDLSQDGSEASYQRFRQLTAAFGTPSRWLAGNHDETPPMQAVCKGSELLEPVIDVGAWRI
VMLDSSIPGAVPGFLADDQLELLERTLDEAPQRHHLVCLHHHPVPIGCKWMEPIGLRNAD
ALFAILDRHPQARAVLWGHIHQEFDQMRGNLRLLASPSTCVQFAPGSEDFQVGNEAPGYR
WLRLHADGGLDTGVSRVNGIHFEVDYSVKGY
>A0A6P1HV58|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodococcus sp. WAY2|TrEMBL
MLHLSDTHLVDETLLYGAVDSEAKLRQIFAEVEASHAAPDALVFTGDLTDKGEPGAYEKL
RDIVEPVAESLGAQVIWAMGNHDDRGHFRTALLREEPSYAPIDHSYDVDGLRIITLDTTV
LGHHHGELEQDQLDWLAAELAVPAPHGTILALHHPPVPCVLDLSVLVELRDQPRLADVLR
DSDVRSILAGHLHYSTTATFAGIPVSVASATCYTQDLNVPAGALRGQDGAQGFNLVHVYP
ETIVHSVVPLGSYDTVGEYVTADETARRLADKGVRIPDAGEDVVPRPTVRV
>A0A379H7Q8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudoalteromonas nigrifaciens|TrEMBL
MAWFDDTYTFNKPSLRIAHVTDCHLLADRNAEYFGVNTATYFQQALEHMALQQLDAVVFG
GDLTQDHSVESYLLFSELISNSTLTCPVFWLPGNHDEIALLEQISGGQIKAAKRLVANNL
TNSLTNNASTDIELLLINSKGLTPAGWVTSEHLNEISDCLAQPVSKQLVFCHHNPLPING
YLDKHMLENGPQLLNTLVNNGNVAALIHGHVHNDYTQCFRELDIYATPASSVQFTKHSKA
WQQQNNGPAYRMLYINSSQGQVHINTDVIWLSA
>A0A0E8C3X3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bordetella pertussis|TrEMBL
MLIAQISDLHIRMPGQKAYRVVETDRYLPPAVAALNRLEPAPDLVIVSGDLTDFGRPQEY
AHLKQMLDALRVPYHVLPGNHDDRVQLAATFADHPYLREAGEFVQYTIEDQPLRFIVLDT
VVPQQSHGALCERRLQWLAQRLAEQPGRPTVIVMHHPPFRTGIAHMDAIGLLAGAPELEA
LVARHSNVERIMCGHLHRTIFQRFGGTIASTCPSPAHQVALDLRPDGPSAFVMEPPGFHL
HEWRDGALVTHHAYIESYPGPYPFHEGGELIDE
>A0A164Z643|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Synechococcus spongiarum|TrEMBL
MAHPTAWTVAQLTDLHLLADPGGYYRGVNSHVQFQTCLRAVCSADPDLILLTGDLGHDET
WAACGLLRDQLATCGIPALVMAGNHDQPQLLRSCLARHASVAPCGVAVGNWLVIGLDSHV
AGCMGGRLSAVQLDWLVGILRPHPGPCLVALHHPPTAIGSPRMDAIALEEPERLLDLLQA
FPQVKGVVFGHVHQAWQQQVPLPLMACPSTAVQIAPIQPSAHPDAPGWRLLRLEADGRLH
TRVMRIVHGQVTPDEPLTQGVPG
>A0A1X6ZUI0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseovarius albus|TrEMBL
MKKLLIFTDLHLKDPGETIIGLDPMERFQQGLMHAVAHHPDAARIILTGDLTHYGRTTQF
ERLKVALGDCPIPVSLMLGNHDSRKGFHNVFPDEPRTAEGFVQQAIDMDGYCLILMDTLD
EPAEDLHSGFLCEHRLAWLDQALSEASDRKVIVFTHHPPMLTGFDGMDSIALRNRLDLIS
RLRKHPQSVQVISGHIHRTISGQVDGIPVSMFKSPCHQMPMCLGPADVHSSVDEPGAYGL
ILLHPEGPIIHTEDYALTGDLNVDTHGSEHA
>A0A6I9YJH3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thamnophis sirtalis|TrEMBL
SHRLRSLVKQLEKGDASVDDLKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDSVPS
EVRDWLASTFTQQMGIMLRRSEEKPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYPSAVI
SALKNIDKWSFDVFALNDASGDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGY
SKYKNPYHNLMHAADVTQTVHYLILKTGVAHWLTELEIFAMIFAAAIHDYEHTGTTNNFH
IQTKSDTAILYNDRSVLENHHLSAAFQLLQDDEEMNILSNLSKDDWREFRTLVIEMVLAT
DMSCHFQQIKAMKNALQQPEGIDKPKALSLMLHTADISHPAKAWNLHHRWTMSLLEEFFR
QVT
>A0A517RM72|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia alba|TrEMBL
MPVHLPAQNRRQFLFTLGAGFITYSTGAFASENQSEDLVYLLNDTHIGEKHPTNSPVPSH
LRQAVSELVNLEQKPACVLINGDLALKDGQPGDYRHFAKLIRPLREAKIDTHLTLGNHDE
RDVFYGVMEEEKPATPPVKSKHISVVQTKHANFFLLDSLHKTMVTQGTLGEEQRTWLTNA
LDAHADKPAIIVTHHNPRLGGDPNHFPGGLTDSVELWEILAPRKQVKAYIHGHIHDRGNA
EHKGIHILNTPATSYVANPKLSTTGWTVAKLSPNGVTLTTRTTDPKHSWNQQTKTLTWR
>A0A7N6A2R8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Anabas testudineus|TrEMBL
HGMSNLFIYEKPKFRSIVHAVQAGIFVERMFKRAYTAAMPDQPAAVVNYLRDVDRWNFDV
FAVNSASSDHALQTLFFELIIRYELNSRFKIPISCLTAFLSALERGYCKYNNPYHNQVHA
ADVTQTLHCLLLRSGLVHWLTELEVMASLFAAAIHDYEHTGTTNNFHIHTKSDFALIYND
RSVQESHHLSASFRLLQDEQMNIFINLTREEWMELRSLVIEMVLSTDMSSHLLQRSKTRL
KYPAQRALSLLLHTADISHPSKPWALHSRWTKDLMEEFFRQGDREAELGLPFSPLCDRKS
TLVAESQIGFIDFIVYPTFSLLTDMAEKIVIPLVEENPGPPDPCNRHSNLWKESSRGLQW
SLAHITAELVTFRSMWTRHTEDNKLKWKESGSNGL
>W2UHB2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gammaproteobacteria bacterium MOLA455|TrEMBL
MSTVHITQITDLHLGANEQETLGGVTTFEGFKAALQASDDQGRGDNLLLLTGDLASDCQA
GAYQLLNKTLAEKQRQALWLPGNHDHLETMEANLTAFPRVRIYEAGAWSIILLDSSKVGQ
PGGHFSEAELQFAEQSLKQLASKFVLVAVHHSPVLVNSAWLDQQQIDNHQRLYDLLAAHG
QVKAVVTGHVHQHHDSLWGNIPVYSTPSSCVQFEQHSHDFRLADKPPGYRWLDLHEDGSL
NTGVEFLKDFAQQCDRSCAGY
>A0A239SKW7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pandoraea sputorum|TrEMBL
MLLCQITDLHITRPGMLACARVDTARALRNTIATINRWTPRPDAVIATGDLIDTPHLSEY
EVLRECLADLEIPLYLVVGNHDHREGLRDAFPEHAYLHSNDPFVQYRVDLGPLTVLTLDT
QDPPSAGGHLCDARLAWLDEQLHACEGRPTIIAMHHPPFDTGIEFMDGYGLSAQGRAGFA
QVVSQHRHIERVICGHLHRSIHASVEGAPGIMASTCVSTAHQITLGLATGAPGSVTLEPP
GFAMHLWQPGAGLRTHLAYVGPHEGPFSFDGEPL
>A0A2G5V0L8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Caenorhabditis nigoni|TrEMBL
MYSENEEDGNNNVIIPMHEVQGPSTSGPMTLSILKKAQTAAMNKISGVRKLRAPSHDGHV
PEYGVNCAREIAVHMQRLNDWGPDVFKIDEHSKNHSLTVITYSLFKQRNLLKTFEIHAHT
LVTYLLNLEHHYRNNHYHNFIHAADVAQSMHVLLMSPVLNDVFSDLEVLAAIFAGAIHDV
DHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDGNCDFLGNLSRKQRLQFRK
IVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNIIVLDKYNDKIQVLQSMIHLADLSNP
TKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYE
TWADLVYPDAQNILDQLEENREWYQSRIPEEPETARTVTEDDEHK
>F9UTE9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)|TrEMBL
MRPLQVIQISDLHLTPRGQVPAHGQQYDPWGKLANIIDDIRRLPTMPDLIVFTGDLIHDG
SADDYQRLHAIIHTMEAEFDCHVRVILGNHDRRAAFYEGYLPADPGPYYASRMRIGNNDF
YFLDSKVSGYEAGWLAPQQLQWLGKHLRQAPTKRAFLFLHHPLDGPTMTNMHYAILQNTP
ALLSVLRGHNLGGVFSGHVHFVSSYLIGDNILNVVAGSAAYAIDCHDPHHHYVHEGSSYQ
IITIDRGQVGVTTRQLLHGKAVIDELTIPDTKFVGRAPQGYESR
>A0A5M3Y4J1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodococcus aetherivorans|TrEMBL
MGSPRGAERIAEYPRPSHTLLHITDTHLVGGDELLYGTVDADARVRQILADIRASQVQPD
ALVFTGDLADRGQPDAYSKLRGLVEPVAQALGAQIVWAMGNHDDRATFRELLLDQAPSTG
PIDRVYDVNGLRIITLDTSVPGFHHGEISQEQLNWLAQELETSARFGTILAMHHPPVPSV
FDQAVLVELRDQACLAEVLRGTDVRTILAGHLHYTTTATFADIPVSVASSTCYTQDLNVP
AGCQRGHDGAQGFNLVHVYPDTIVHSVVPTGSYITTGRPSTAEDAAQRLAEAGIRIPENP
DVTVRV
>A0A8D1EDR3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sus scrofa|TrEMBL
MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD
LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR
SEEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS
GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV
HYLLYKTGVANWTLEKEILNIVNSASLDSHEKKKATNNCHITFRSDPAILYNDRSVLENH
HLSAAYRLLQEDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE
AIEKPKALSLMLHTADISHPAKAWELHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS
TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNNISSSDAKR
STVKSSGSEGSAPINNSVIPVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKAR
LAAEEKQKEMEAKSQAEDGAAGKAEKKASGEAKTHPVNGTRTNKSDNPRGKNPKAEKSAG
EKQQNGDLKEGKNKTDKKDQSSVGNDSKKADGSKE
>A0A292ZN01|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sphingobium fuliginis (strain ATCC 27551)|TrEMBL
MLIAQVTDIHLGFDPDNPAEFNRKRLDQVLRALNDGPNRPDLLLATGDLTDRGDADSYRR
LANAFSQCDFPVWPCMGNHDDRAHFAAHFPHIPQEDGFVHYAIAQDGRRIIMLDTLEPGR
HGGAFCERRAQWLAARLDEDSITPTLIVMHHPPVEVGIDWMNTHPEEPWVRRFAATIAGR
PNLQAILCGHIHRSAVAPWKGTTIAICSSTAPQLALDMRPMDPDAPDNRPMIVADPPAYA
LHRWTEEGLITHFETADDHVMLAKFDGSMQLLVRTLMNERP
>A0A347W7Y1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Komagataeibacter saccharivorans|TrEMBL
MRPRHDGRQKAGKEVSLSTITIAHISDPHLPSEMAPPRLTERLNKRMFSYLSWTRRRRFI
HRPEVLARVMEDIVTSQVDMIALTGDLTNMGLPGECRQARRWLEQMPAPCTVIPGNHDTL
VHDDWQATVGLWQPWMGPLPFPFVRRIGNVALIGVSTAVPTPWFRATGRIGVHQSRRLRT
ILHGAGQQGLCRIVMIHHPPVPGLAVTRKALTDTRNFSECIAREGAEMILHGHIHLSTLS
SLPGPAGGVPVIGIASASARSDDPLRTAGWNRITVSPRGNGYEIGVTRRFFPADGTAGTT
RETIFDPSPPSRCFSGISTP
>A0A086L3S5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii p89|TrEMBL
FICRPLFGSLAQMFPAQLGDRAAELRKNRNKWKSIIDGHERR
>A0A086L3R1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii p89|TrEMBL
MLCTAKLLQTMGGTMQILSSPSRGMLVSFQIRTRARFRLLDFQKDFRASFSQQRRQRIIS
LGLAPETSRALQFLCKDVGIQFTACYCLRHLRESLAT
>W1EGN5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae IS53|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYVVDDFATRLLFID
SSHAGTSKGWLTDETISWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDDNISCPTEER
>A0A183GAQ8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Heligmosomoides polygyrus|TrEMBL
LGSWGIEHGSLCDTIVTTVDGQKFDTKDLDNDRGMAMVADWSLPIFEIAEKHAKTVLSRL
TYTVFKQADLFRIFKVSPIKFFNFFHALERGYWDIPYHNRVHAADVLHGCYYLTCHPVRP
LIGPTTSPDSLLPPPLTLAAPISASMSTLELMALYTAAAMHDYDHPGRTNAFLVAAEDKK
AILYNDRSVLENHHAAESWRLLQLPENNFIETLDPAETKRFRYLVLEYILATDLKQHFEI
IMTFNEKSSEMELQNESDRLLMAKMVIKMADINSPTKPYSLHRQWTDRICQEFYEQGDEE
RRRGMPITPYMDREDAQVAKLQDSFIAHVVSPLALAMNEAGLLPILPGLVEPEMMINLKH
NHQKWLQEIDNTSGEPGKPMTNCLGKGLHSYSVQ
>A0A653MX62|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. 8O|TrEMBL
MPSLPTPSTDSSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIERVQQEQPQIDLILAT
GDLSQDGSEASYQRFRQLTSAIDAPTRWLAGNHDEIPPMQAACQGSELLEPVIDLGAWRI
VMLDSSIPGAVPGFLADSQLELLERALGEAPQLHHLICLHHHPVSIGCKWMEPIGLRNPG
ALFAVLDRYPQARAVLWGHIHQEFDQQRGNLRLLASPSTCVQFAPGSEEFQVDSEAPGYR
WLRLHADGRLDTGVSRVTGIHFEVDYSVKGY
>A0A376KN64|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLQAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPGEARVYW
>A0A2J7Y920|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas putida|TrEMBL
MSPPDQSRPVHVVQLTDAHLFADPAGSMLGLKTRDSLRHVVAQVRREQPLVDLLLCTGDL
SQDASVASYEAFRELTTPFAVPTRWLPGNHDEAQVMAQVAPELVQAVTDIGAWRVVMLNT
AVHGATHGFLQDDQLAVLEAALKEAGERHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDI
VEGYPQVRALLWGHVHQEWDEVRGGRRLLATPSTCIQFAARSEDFQVSEEHPGYRWLRLH
ADGRLETGVERALDFEVQLDFDSPGY
>A0A2C8F4E5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas lundensis|TrEMBL
MPSVSTLTTEDPVLLVQLSDSHLFADANGSLLGLNTARSLQQVIDLVSAEQPSVDVLLAT
GDLAQDGSVAAYQYFRQATAALAPVARWIPGNHDDVQQMREAAIQSRLMEPRVDVGNWRI
TLLHSNVLNKSYGYLEDDQLQRLAQSLSEAPERHHLVCLHHHPVPVGCQWIEPIGLLNAD
AFWAVVDRFPQAKAVLWGHVHQPFDQQRKAVRLLATPSTCFQFAPHSEDFKVSSEAPGYR
WLQLNPDGTLHTGISRVAHFDFEPDYSQDKY
>A0A4Y2KBU5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Araneus ventricosus|TrEMBL
MRLDARKPAQKRRIYAMSKWITSVIVRLRELSNHLNHGEIPMDVLQQTVTYAVSVLEAIY
LDETKRLLDEDDELSEVQPDAVPPEVREWLASTFTRQMSTTRRRSEDKLRFRSVAHAIRA
GIMVDRIYRRLSSSSNLQMPAQIAQLLKMSTASLESFLVQIENGYERYRNPYHNNMHAAD
VTQTVAYLLCQAGLANWLTDIEIFATLFAAIIHDYEHTGTTNSFHVMSGSETALLYNDRA
VLENYHVSQSFRLLRDDENSILNNLSKEEYREFRSLVIEMVLATDMSSHFQQIKTMKTLL
CHSDFSSMDKAKVLSLMLHCCDISHPAKDWNLHFRWTQRLMEEFFRQVSKVVSFFSLRLK
TDRVILDIEAVHNFPKFSSVLTSHFESTPVLFWD
>A0A1R3TJP8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Agrobacterium rosae|TrEMBL
MAAGITPRPNLLPESSPMKIIQITDTHLRLSGQSVNGVDPEKQLRAAVTDILDKHMDTDL
LVMTGDLCNFGDPEAYDILRDILAPVPFDVRLMLGNHDDRPNFRSAFPEHPHDENGFIQS
FMDTDFGRLIFLDSHEAGVIGGIYGEDRMAFLADALASAGNLPVTIFIHHPPMDCGIAHF
EKIGMHDDGAVMRVLAAHKGGIRHIVFGHIHVPLAGTSAEGIAFSSGQACAHRFITDLTS
PKPYWTGGNPCYRIINLDAQGLRAYSVEVGETIMGQAPICDGP
>A0A3G8C037|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. R4-34-07|TrEMBL
MPSVSAVNPDAVLLVQLTDSHLFAEADGTLLGMNTRESLQRVIELVREQQPSIDLVLATG
DLSQDGTLASYQQFRDMTAPLGAPARWIPGNHDEPQVMAQAAVHSDLLEPVVDVGNWRIV
LLDSAVPGSVPGYLQDQQLQLLAQALSEAPNRHHLVCFHHHPVSIDCAWMEPIGLRNPDA
LFAVLDRFPQVKAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEHFKVSEQAPGYRW
LRLHADGRLDTGVERLQGFAFQVDYGSNGY
>A0A0H5DGM1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Phaeobacter italicus|TrEMBL
MKLIWMSDLHFQHSGEILGHDPQLRLDAAIAYINQHHSDASYCVISGDMAETATARNYAD
LADRLDQLAIPCLPMVGNHDDRDLLRAQFQVPDSCMDGFLQYSVDTPAGLILCLDTLKPG
ASEGEFCAERARWLTNTLDAAQDRAVLLFLHHSPMPLGLPMQDSARLEHGARFLEIIEGR
ANVRHLCVGHVHRSVTGTIRGVPFTALRSVLYQAPPPQPEWDWNSFTPSVEAPELAVVSF
EQDSVTIQPLQFCPYDVGTSGRGQS
>A0A1V4WE07|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Syntrophorhabdus sp. PtaB.Bin006|TrEMBL
MKPVSNTRVIVVLVILLLFFPLLGYSADHRSFAIIGDTGIGVNDLHYRTFLQKIESEGID
LIVHTGDVIDKPGSQGEWKRFLEITGNKPTVLISLGNHDINTVKSLKVYENLTGRTPYFT
FAMNETQVIVLCTELPGEWSRITGKQLAWLSAELAKPFRYRFVFLHRPLFPAIYYMGASL
DKFEQDRNLLHALFIRHHVNMVVAGHEHLYNRTIRDGIAYIISGGGGARLHAFTEEQGGF
FHYIIAKRNKEGYVLRVYDFEGKVRDEFEIKNEVRNG
>A0A0M8KPK6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Brachybacterium sp. SW0106-09|TrEMBL
MGGGAGLNPVDSDTCATPAAATVPGMRILHLTDTHLYGDPSARHYDRIDTADALRGLLSR
LEGLTGIDAVVHTGDASEDGTAESYRLLHEILDPFAAALDAPLAIVMGNHDVSAVYGEAV
APGERIAPSQDRVVPLGGGARVVVLDSSVPGAGYGHLDPEQLDWLRGVLAEPAPGGTVLA
IHHPPLVAATPLLRGLDLDGLDELAAVLDGSDVRIVLSGHYHHEMTGEIAGIPVHVAPGI
TNVVDPVGAGADEQSLALSGMSLVELGEGAPRVVSSVFPNAGDTLADVERPVYRFAPEQV
AQILEAAGR
>A0A6I9NPT2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Notothenia coriiceps|TrEMBL
MRLRCLVKQLERGEASLTDLKKNLEYAALVLESVYVEETRRLVDTEDELSDIQSESVPSE
VRDWLASTFTRQMGLMLRRNEEKPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYPPSVIS
VLKHVDKWSFDVFALNEASGDHALKFIFYELLTRYDLINHFKIPISAVVSFIEALEVGYS
KHKNPYHNLMHAADVTQTVHYLLLKTGMVHWLTELEIFAMIFAAAVHDYEHTGTTNNFHI
QT
>A0A081S3H3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Marine Group I thaumarchaeote SCGC AAA799-E16|TrEMBL
MIIVQISDLHVGSQFLEEKFNVLVNEVNELNPDVIVITGDLTNEGLMKEYEKCKSLLEKF
NTKKIIAISGNHDYRNTGYLLFKKFFPFQTVNELSDDVVLVTVGTARPDRNEGEVGYRQN
LWLERTMKKFKDKIKIVAMHHHLIAIPDTGSDQLTVVDAGDVLRTVLDSKVDVVLCGHKH
RPWAWNFGTLTVVNAGTATSERVRGLFENTYNILTIENKKVQVDLKIVGGKRVPIDEIVK
NYSQFHDELDNV
>A0A2L0ER82|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sorangium cellulosum|TrEMBL
MERAEPVELRVVGCHGGETPKHRTCAFLVDDVLAIDAGSLTSGLEVKEQMRIEACLVSHA
HLDHIRDLATLADNRCQLECPPLVAAGTRETLRTLKKHFFNGVLWPDFAVIPTPARPTIQ
YLELKPERPTVVAGRVVRAVHVSHTIDASAFVIEGSGGSIAYSGDTGPTERLWEVLNQQQ
DLRALLMEVSFPDREQRLATVSGHHTPQTLAAELRKYRAPKDLPTMLYHIKPVFQAEVER
ECAALQGLNLEVLQLLDHFVL
>A0A3B0W7Z9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MKRYSKVDGEHYGTLCEERLAWLVARLEEGGKRPSLIFMHHPPFTTGLCYPDQLMCRNGD
AFGDIIARHPQIQAIICGHVHRDVVTHWRGVPAYVTSSATFSNGLILYPVDDVDPLFEPP
MCRLFQWENGRLTSHISFIGSYLFGLSEGVPTPPSDLQ
>A0A3B0YI59|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MNDTTPSTGLRFVHLSDPHLTTLEAVRWHQLLSKRVLGYLSWRRGRRAEHRREVLDALVD
DMHEARPQHVVITGDLTHIGLPDEFRQARYWLERLGEAGDVTIIPGNHDTYARHAWSDTF
ALWEPWMRSDTVTGHMPITSRDELFPSLRIRHGVALIGLSSAVTTAPFLATGELGEAQLK
RLAVVLRETGVQGLFRVVMLHHPPGEGTEKWRKRLTDTAALARVLAEYGAELILHGHSHR
ALHSSIQHAAGDIPVFGIPSASAVGRKPGRAAQYYLYDVRPEGAQWRINVRVRAYQRERH
CFTLEHEYHLSAPRMASTKC
>A0A238J5B3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Boseongicola aestuarii|TrEMBL
MIGLDTLAEGQGAGKLSSDSLSFLQNALSQTGNAPVLLALHHPPFACGIRFMDKIGLTNR
QALRDVLTGFDGTLRIVCGHIHSMIVSDIAGHIAISAPSPASSFAYDLRLDAPVGYMAQG
DGCLLHRWDKGFQSIRIAPAAGSGPFPF
>A0A1V6H319|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Verrucomicrobia bacterium ADurb.Bin070|TrEMBL
MSENCLTLLAVSDLHHMGLARQTAQAQQMRGELAQTLLKKVFLRLRHMGITPDATLVLGD
LVEDGADRNAALDFVSLHGELTRSGIPCLVVPGNHDGDPAAFNALFGSTPGLHKIGGYGF
VLFNDTYSENHECVRAAEDLALLKKCAEENPELPLIAVQHPPIYPAIDSHYPYRPTNAAE
IIDAYQKSGVILSLSGHFHKGQKARIHERILYHTVPALCEQPFRFSLIRLVDSRVEIEEL
CLGLQAPNLIDVHCHTEHAYCGTTVDTAPCVALSQALGVSTLCITEHAFQLYFDKARAMN
FRWQSDPAMVKAVWETPGRGRMAAYQQFAEKLRSPFVKIGLELDLFDDGRLLLAPEDAEH
DWDIFIGAVHAVQGFMPGQTTQQEAERLFLRDVERLVEHDIDVLAHPFRFFKRNRLEVPE
HLFAAVAGLLADSGVAAEVNFHTYQPEAAFIRLCVEKGVKIALASDTHDLAEAGEFWPHV
NILRQAGITPKMFPETLFTF
>A0A653UUH4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Alteromonas sp. 38|TrEMBL
MKFISTLLLILIVSGCQAHQNAQEHSQKQKQAQQDIQSSINTISPAFELITLGDTGGIED
GNLSSFLLRSVEDENFISLDAGSLVNGINVALENKAFDSLTTTPDPSLNPNGNILHHHVK
AYLLSHGHLDHVVGLLIASPDDSSKPIYALSSVNQTMSDTYFNWQAWANFTNRGIAPMLN
KYEVIDLTPQKTVEIKDTALSVTAFSLSHPLESTAFVIEHNNDMFVYFGDTGPDEVEKQG
KLDAVWRYLAKQMQHKTLRGISIEVSFDNTRPDNLLFGHLTPKWLMQELTTFHALVEDKE
QLSNMKVIISHIKYSLKRGTDPRAVIAQELESANALGFNFILAKQGQVLAL
>A0A1Y5RDB9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pacificibacter marinus|TrEMBL
MKLLQITDIHLTALGKTIGGRDPNANFAKALNHAITHHPDAEALIITGDLSDWGDAADYE
RLKAYLGEVALPVHLCIGNHDDRQTFLQVFPETEGSDGFVQSVIPLSLGHGILLDTWGQD
THAGQFCEKRAAWLEQTLDTLEGPVWIFMHHNPVPIEIAPMDEIMLLDADRFAATVAPHA
GKIRHIFHGHCHMHLSGSLHGIPFSAPRGTNHAGWPDFAATKLLSGADLTESYSVIFASE
TTTMVHMVEYGYAGEIRGEGSPDYADWDQLTMVR
>A0A0D6LZS9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ancylostoma ceylanicum|TrEMBL
MIAFLIAYCFSGSLCDTVVTTVDGQQFDTRELDGDRGMSMVADWSLPIFEIAEKHRDTVL
SRLTYTVFKQADLFRIFKLSPIKFFNFFHALERGYWDIPYHNRVHAADVLHGCYYLTCHP
VRPLIGPTTSPDSLLPPPLTPAAPISSSMSTLEVGGHSSVSGQSQAQYGFKLMALYTAAA
MHDYDHPGRTNAFLVAAEDKKVLRSQSLAQHSYLVLEYILATDLKQHFEIIMMFNEKSSE
MELLNESDRLLMAKMIIKMADINSPTKPYGLHRQWTDRICQEFYEQGDEERKRGMPITPY
MDRTDAQVAKLQDSFIAHVVSPLALAMNEAGLLPILPGLVEPEMMINLKHNHQKWLHEID
SANAESGESQRLTTLWISVQVHSE
>A0A142YE84|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Planctomyces sp. SH-PL62|TrEMBL
MPIHLPPTTRRGFLNVLAAGGAALAWPGARSAVAAGREEDAADYVALLADTHIKSDPDMV
VREKFHLSGNLRAAVADILAQPRPPAAALVLGDLALKNGRAEDYRQFLTLVEPLRERGIP
VHLTLGNHDDRRNFLESFAALGAAVGPVEDRCVGVVEAAGVRLAMLDTLDQVDQVPGLLG
DSQRAWLTKTLDEAPDAPTLVLFHHHLDDVPGALTDAKPLLEILRPRKQVKALVFGHTHT
WRRAEDDGLHLVNLPAVAYHFNDPQPLGWCRLEPHRDGQGATLELRCVDGDRSKHGERIE
LAWRGA
>A0A1W5DFY8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serratia proteamaculans|TrEMBL
MMRKVLALCLSGYSALALAGFDVVALGVDGGVSDGNLTSYLIRNDSQPQYLALDAGSLLP
GIAKGLEKGSFPQVTPELAAPYTPQGYIFRQLIGAYFISHGHLDHVAGLIIGAPEDTKKN
IYAQADTILTLRNHYFNWKAWPNFTDSGNGSRLGTYRLQTVRPQQRVTLGVTGLSGVMYP
LSHDRYPSSMLLVSDRSGSFAYFGDTGADALEQSRNLDSAWRVLGPLIEQKKLKGMIIET
SYPNEVEDKNLYGHLTPAWLLKELKSLTQYSGGEGSLKDFPVVISHIKPSLKQGEDVRAT
IKQQLDQGNNLGVKFILMEQGDRQTF
>M3XT07|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mustela putorius furo|TrEMBL
MDDHVTIRKKHLQRPIFRLRCLVKQLEKGDVNVVDLKKNIEYAASVLEAVYIDETRRLLD
TEDELSDIQTDSVPSEVRDWLASTFTRKMGMMKKKSEEKPKFRSIVHAVQAGIFVERMYR
KSYHMVGLVYPEAVIVTLKDVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIP
VSCLISFAEGLEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMMNMWLPRQQCLEISY
SKLCHPIQNTTGTNSFFVQFLRSDVALLYNDRSVLENHHVSAAYRLMQEEEMNVLINLSK
DDWRDLRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPEGIDKAKTMSLILHAADISHPAKS
WQLHHRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEPTFSLLT
DSTEKIITPLIEEASKTDTSSYGASRSLCCLITFHSVDLFRRSNMKGTMNDGTYSPDYSL
TSVDLQSFKNNLVDIIQQNKERWKELAAQESLTLVQRVSVIHY
>A0A2K8P9G7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces lavendulae subsp. lavendulae|TrEMBL
MIVIAQLSDVHLDGGTRAAERTRAVLEYLDALPYDLDAVLMSGDIADHGTEAEYEEARKA
LATRHPAVVCPGNHDERVAFRRVLLGQEEPSAEPVDQVLRGEGFVLAVCDSSVPGKHEGY
LEDSTLAWLDGILTGTPHEVPVLVAFHHPPVPLHTPYVDGIRQFGEERLAALAERHPHLL
AFLCGHAHTAAATTFAGRPLLVAPGVVSTLRLPWETQTDPGHHVHLDEPPAVAFHVIGDD
GRLTTHYRVVVDRP
>A0A086PPR5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii VAND|TrEMBL
MRCLIPQRSAFANLCTLVAAAAHDVGHPARTNLFLQNLLHPLSIVYNDVSTLENFHSALL
FRILSEIPDSNVFSGLPQETFRIARQNIITLILATDIKQHFETISRFRLRRNSPEFNFLK
KEEDDWLVRKMIFKIADISHATVAWDAHFFWSCKVNAEFYAQGDAEVRLGLPVSPLCDRE
KHFEMGKSQVAFLNFVVEPLLRELEAIEALVLPLGTCPIISTELLPNFAENVQQWKAIDT
EKKLVILERVILDYGGYGAVPPLTESQRRQLISECCRPLEGLQESACESLRVGPREV
>A0A7U8DA32|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Burkholderia mallei JHU|TrEMBL
MPARCRPRTLKDRKIVRQAIKRCNQISHPVAPHISPLLSITYQKRQPARTTLNDRYFP
>A0A0N0V261|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Magnetomorum sp. HK-1|TrEMBL
MTSTNNSDTNQINKNVADSQRQAPKAKPVPPTRIPPALEIQQLRQKLQRLELAMEISRQF
SATLDVDKLMQTILDKVAHVTNAEAGSFWIKDKQTNMAICHVAVGPVKHKVLGLKLKSGT
GIVGWVIENKQKTVVFDTSLDERFFNKVDEKVNFITKSILCVPLLVNNECVGAISLINKK
TPVGQFNQQDVDTLELLAMSGAIAIKNAQLFQSERKIKELKTLLTISREITSTLDLDRVL
LAIVNLGSQVIFYKRAVIGLIGINNKVTLSAETNIAQPDMTEPKNKQIKEIMKYVLDSGN
PVHVVNFQIDSPPKNVPKIIIDYLKQFELQCISIMIMSDAEGKLGIISMEGTYSSLVVKE
SNDVVDIVVNQATIAIRNAQLYKNMPSHTLSGKLKSSVTETTRSWKKTLVFFLSIVLILI
MINAIKVTERVTAIVEVIPSQIMKVTSQTDGVVQRINFSEGDLVKNDQTIITLDSSLLRL
ERAKLTKDINIQSGELRRLQSEGAPFEVHLKNLEIGKLRNQLKIINKQISFTKITPLIDG
RVLTQRTDQLINKQIMKGEVIAEIAANDSKIIEVIIDEADVHRVKANNNSYITLQAFPDI
LINGRVHSVSWTMTDPETEDEPKGYKAWIIGQEINDVPEIRFGMTGKAKIVTGRKTLFEI
YFKPMCDRIITEFRLKFTKNNYSESEIGKN
>A0A2X1UBH6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mycobacterium xenopi|TrEMBL
MDRPRVAEYSRPDHVIAHISDTHLVAGDGDLYGDVDADARLSELLLRLEASQTRPDALIF
TGDLADTGQPGAYRKLRELVEPLADRLGAQVIWVMGNHDNRASLREHLLRETPTMAPMDR
VYDIAGLRVIVLDTSVPGHHHGQVAADQLQWLADQLAEPAPFGTMLAMHHPPVPCVQDLA
VMVELRDQAALADVLRGSDVRSILAGHLHYSTTATFAGIPVSVASASCYTQDLLTPGTRG
RDGAQAFNLVHCYPDTVVHTVIPLVAGATVGRFVSPDAVRRELADAQVSILPATRIPRIA
PQLARHE
>A0A5P9CMJ2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio aquimaris|TrEMBL
MKTIVQISDCHFNLNKANAEKALVHTLDFINRLKFDYLFITGDICESPTIPQYQIFARLI
SEHISTPNIYAIAGNHDCIDMIKSAFKDTWIKVAEQVSIERFNFMFIDSSKKPKKAMMLG
AGRVASKDIKRIDDANQETVVVIHHPIFENDCDWFNEIGLENQKEVATSVLNNENIQHII
CGHGHSFIQTKRQHTTQIMSPSTSYGFDHDSKVFLKNDRVGAVMIQVGETITSQEIRIPS
RIERTVKAI
>A0A2R3J0Y5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas aeruginosa|TrEMBL
MSRHSNTPDTDASVLLVQLSDSHLFAEDGARLLGMDTAYSLEKVVERVAREQPSIDLILA
TGDVSQDGSLDSYARFRRLSAPLAAPLRWFAGNHDEREPMQQATAGSDLLEQVVDVGNWR
VVLLDSSIPGAVPGYLEEDQLELLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRQAPGY
RWLRLHADGRLETGISRVDDIAFEVDYDTAGY
>A0A1V4IL00|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium chromiireducens|TrEMBL
MALYTISDLHLGFNVEKPMDIFGDKWKDHCDKIKVNWVSKITEEDMVLIAGDISWSLKEQ
DSKYDLDWINELPGKKIISKGNHDYWWVSISKLNRKYENTKFLQNNFYSYEDYAICGTRG
WMCPSGEKYSDKDKKIYDREQIRLRLSLDAAKKNGFEKIIVMLHYPPTNEKFEESEFTKI
IKEYNVEKVVYGHLHGPVLLGKVLDGYLDGIEYILTSADYLDFNPKRIL
>S6D0N5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Halorhabdus tiamatea SARL4B|TrEMBL
MTGGEFRSGDPETGGKRGTLMARLDRPSAPEPVRLAAIADPHVSTRAEGTSKLFEHSLEH
FTAAVDDIASRDVDAVLSPGDLTKDGEAWNADAVADALEALDVPLYAVPGNHDVPKDGDD
HDAIAVADFADRFGPGSYPFHEAVGGLDVLGVNSAGTADRLADTHDGHVDADQREWLAGK
LQRTDDPLIVVHHNLASVTEQLRRHRDRVVDDMAIPPTMRETEAFVDVLAEGDASLVLTG
HFHLPLTGVDRGVREIATPTTCSFPQSYLLLDVGPTGTDVRLVPIATQDGLELAHDRRAR
DSTTARGLTSIGAARLASMPLTVED
>A0A1W1E6B9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MAPNFIQISDCHIDDNPQSMGVDTHQNLARIINEITPIKSDALLISGDLTHNGTPDSYAK
LKELLTPVQSDIFVIKGNHDSDNLMTLFSECLFKKISLGKWDIISIDSVQANKTSGYLSK
NALFALDDQLNQSTADFVIVMLHHPIVPMNSTWDDALSLENPQDLLAVLDKHAKIRAVLF
GHAHESAEFNRQDLKIIACPSTAVQFTDEKRIGFNDYTLNDDGRLECETRWITQ
>A0A1C3K264|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Orrella dioscoreae|TrEMBL
MLIAQISDLHIRLPGQKAYRVVETDAYLPPVVDALNRLDPRPDCVVITGDLTDFGRPAEY
AHLRHLLAPLQLPFFLLPGNHDDRQALADAFPEHAYLRTDGPFVQYAVEQYPVRILALDT
VVPFKGHGALCAERLQWLETELAREPGRPTLIAMHHPPFKTGIAHMDAIGLLSGAPELAA
LVGRHPNIERIICGHLHRTIYARFGGTVASCCPGTAHQIALDLRPAGPSAFVMEPPGYQL
HTWQGGALTTHSAVLGEFPGPYPFHEEGALIDE
>A0A486MP24|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYVVDDFATRLLFID
SSHAGTSKGWLTDETISWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A045J9Y3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mycobacterium tuberculosis|TrEMBL
MHRLRAAEHPRPDYVLLHISDTHLIGGDRRLYGAVDADDRLGELLEQLNQSGLRPDAIVF
TGDLADKGEPAAYRKLRGLVEPFAAQLGAELVWVMGNHDDRAELRKFLLDEAPSMAPLDR
VCMIDGLRIIVLDTSVPGHHHGEIRASQLGWLAEELATPAPDGTILALHHPPIPSVLDMA
VTVELRDQAALGRVLRGTDVRAILAGHLHYSTNATFVGIPVSVASATCYTQDLTVAAGGT
RGRDGAQGCNLVHVYPDTVVHSVIPLGGGETVGTFVSPGQARRKIAESGIFIEPSRRDSL
FKHPPMVLTSSAPRSPVD
>B7PNB0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ixodes scapularis|TrEMBL
MAQTQIKEQTNWLKKFLNLRALPKPVHPRTVLERWGFLKMGAVAEEIAADDPSTMSGDHR
TVINGSPSQYVKLNVGGSLHYTTIGTLTKHDSMLRAMFSGRMEVLTDSEGWILIDRCGKH
FGTILNFLRDGSVPLPESARETAELLAEAKYYLIQALVESCEAALQKKESSTEPICRVPL
ITNEKEGNLLISTSTKPLVKLLINRHNNKYSYTSTSDDNLLKNVEMFDRLSLRFCSRVLF
IKDVIGSNEICCWTFYGHGKKVAEVCCTSIVYATDKKHTKVEFPEARIYEETLNILLYEN
RNGPDPELMQATSTRGAVARTTTCYTSDDEDERRAPLGSSSSCGGNCARDSRDSCHLGRI
RSTKQSS
>A0A1L3LI83|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sinorhizobium americanum|TrEMBL
MRCRIATTLMTKFIIFTDLHMVPDGTTIIGIDPYRRLANGIAHVNRYHADADRVIFAGDL
THHADRASYERLKDLLSELVPPAAVMLGNHDRREVFLEVFREAARDENGFVQQVIDFPDC
RAVLLDTLFAPPYDYPMSHAGHLCDRRLAWLDRQLGSAGDRPVLIFMHHPPHASGFAGID
MIRLINEEQFYGLVKRHGNVRHIFAGHVHRTISGSSRGIPFSIFKSPVHQQPMPFDIADA
SLSVDEPAAYGIAVVTPDGVLVHTEDYEIAKRDAAVA
>D4MUM9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Anaerostipes hadrus|TrEMBL
MKVIQISDFHLRGDGKLSFQKADTMKALHQTIDYFCSMKDYELPEFFVVTGDLSEGGTRE
GYEFMREGLRKLPRPVYIVPGNHDKRDFFLEMFTEETPVKEDIKPYICYTIDEYPVRVIV
IDTSKPSCHSGGLSDRVAEWLEERITEYPEKPTLVFTHHPPFVTGLPAMDEGFDQADRLA
QILNKHENVTLCCGHMHTAIFTSWHKIPCVTCPPIAMQMEVDFRGKNDINLTEEEKKEEF
KGGGDRFFLGNPGYLIHDLQGDRINTHYQTIPTGADYSGPWPFKYYEGEED
>A8ITN3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chlamydomonas reinhardtii|TrEMBL
MTHSNVERFRFLAVVQVLTVLQRIDDWQFDAFKLNEVSGGRPLSLLSYALMKHNGLVDKF
QMDDHRLVKFLMRVEDGYPNNPYHNRIHAADVLQSLHVLVVRGGLKAPDHTYCDDVSLAS
CYLSAIIHDFEHKGVNNDYLIRVSDGLAVLYNDRSPMENHHLAASFQLMNSDEYNFLRKM
HNKQRETLRKQIIEMVLATDMKQHFAIHSIGGKTMRSSPHSTSQDGHKVVDEDQRSLVLQ
VALKCADLGHLASPRIVHKKWVQYLEEEFFRQGDREKQNNLSVSPLMDRDKNGISKSQVG
FFDIVALPLFQSFAQAFPEATPMLDAVKDN
>A8HNW2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chlamydomonas reinhardtii|TrEMBL
DSWEFDTWALQEATQGHALSVLGFYLMQRAGLVSRFKLSAPQLARLLRAIESGYVDNPYH
SAIHAADVLQTMHVIIHAAQLHVHYLDALGLLASYYAAIVHDFAHPGLTGDFLIASSDPL
AIRYNDRSPLENHHCAASFGLLRRRELDALAPLSQSERNAFRKQVIELVLATDMKQHFSI
LSHFNTYPAPRPVDDTERLLSLQLALKCADVGHLGESLEVHKKWLSNLEEEFFRQGDKER
ELGIPISPLFDRSKQGVSKSQVGFYDFVALPLVHALSSAFPGSKPLMRW
>A0A0H3B2T0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Yersinia pseudotuberculosis serotype O:3 (strain YPIII)|TrEMBL
MLLKYLSIKSASDKIKSGLLKTGVILSFSLFSSLSTAAFEVVALGVDGGVSDGNLTSYLI
RNDSQPLYLGLDAGSVLPGIARALEKGHFAAITDAMAAPLTRQGYIFRQSINSYFISHAH
LDHVSGLIIGSPDDSKKTIYASADTIDVLRNYYFNWRVWPNFTDSGSGARLGTYRMQVVR
PAQSLSLGLTRLTGEMYPLSHDKSPSSMLLISSNNEFFAYFGDTGPDDVEKSKNLDTVWR
KLAEKVTQQQLKGMIIEVSYPNDVADNKLFGHMTPTWLLKELKKLEQYSGEGQPLKGLPV
VISHIKPSFQQGQDVRKLILSELQQGNDMGIEFILMEQGDSQKFQ
>A0A0H3NMK0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Yersinia enterocolitica subsp. palearctica serotype O:3 (strain DSM 13030 / CIP 106945 / Y11)|TrEMBL
MFLTYISTQPTSAANKTSTNKCRNRLFSAGLTLSFSLYSTLAAAGFEVVALGVDGGVSDG
NLTSYLIRDDSQPVYLALDAGSVLPGIAKALDKGNFSDITDEIAAPLTRQGYIFRQRINS
YFISHAHLDHVSGLIIGSPEDSKKTIYASADTIDVLRNYYFNWRVWPNFTDSGSGTRLGT
YRMQLLRPAQSLSLGLTRLTGEMYPLSHDKSPSSMLLITRNNEAFAYFGDTGPDEVEKSK
NLDTVWRKLAEKVKQQQLKGMIIEVSYPNEVDDGKLYGHMTPKWLLKELKNLEKYSGEGQ
PLKGLPVIISHIKPSLQQGQDVRKVIASELEQGNDTGVDFILMEQGDSRKF
>A0A447J894|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Morganella morganii|TrEMBL
METPLHLPVADGAAVRILQITDTHLFAGETDTLLGINTLHSYHAVLDAIVKQQLPADLIV
ATGDLVQDQSTRAYQRFTDGIARLPAPCVWLPGNHDYQPSMAQELAAAGISPSKQVLLGD
QWQILLLDSQVQSVPHGELSDDQLIWLDNCLAPAA
>A0A5C5V6R9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Posidoniimonas corsicana|TrEMBL
MLTLMQISDLHFGPHYLPKVGEATLRAAHDLRPGVLVVSGDFTQRAKPVEYQAARRFLDD
LPAAPQVVTPGNHDVPLYRVWERLTEPYKHYRHYISEELDSVLRVEGACVVSLNSAAPYH
AITNGRIRNHQLDYCAEQFQRAGDGELRVVVAHHHFAPAPDYEQTDVMPRAKRAMDRFES
VGVDLIMGGHLHRAYIGNSLDIYPGSRRQRGVIICQSGTTTSRRGRAREREKNSFNLVEV
SDRSITITHWMYFSDTDGFEPISTHRFPRWPNRNLSA
>A0A7U9HE50|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces lividans 1326|TrEMBL
MLVLAHISDLHLDGSPRATERAERVRERLWRLPGRVDALLVTGDIADHGTEAEYEEAARV
LGLRDGSAPFPVLTCPGNHDSRAPYRKALLGRPAADGPANEVHVFDGGAVLMCDSSIPGS
DEGELDGETYDWIEASLDGLDDGLPALLAFHHPPTPVHHPLPDSYRLRHPERLAALLERR
PGIAGLITGHAHSPAATVFAGRPLVVGPGVTWTLRLPWEGEQVADRDAPVGLAFHVLDDA
GRLTSHFRTVT
>A0A4U1FCK3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Monodon monoceros|TrEMBL
IAEQGEAAKWVSLPVSGLSMGRLFCVIHKSMNEAMADYMDKAPGRLLDTDDELSDIQSDS
VPSEVRDWLASTFTRKMGMMKKKSEEKPRFRSIVHAVQAGIFVERMYRKSYHMVGLTYPE
AVIVTLKDVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVCCLIAFAEALE
VGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTTN
NFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNVLVNLSKDDWRDLRNLVIEMVL
STDMSGHFQQIKNIRNSLQQPEGLDKAKTMSLILHAADISHPAKSWQLHHRWTMALMEEF
FLQII
>A0A377ZNC9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALREPPDAVVVSGDIVNCGRPEEY
QVAARSSAA
>A0A0B2VNB6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxocara canis|TrEMBL
MASSKFRKMLNKELSHFAESSKSGTQVSQFIISTYMDKEDDDPQMPQLEVSHAEPPTPST
STTSESPQLSLLGKAKTAAMSRISGVRKLRSTYGGQVPEFGVEGQRELAVHMQRVSTQQW
STSDHYPFKHFPLAPFIHYMTGCADASLKCAFLNSTDGLLDEWGPNIFKINELSKGHSLT
AITYTIMKNRGLLKTFEIPPGALVTYLLHLEHHYRDNPYHNQIHGGDVAQSTNVLISCPS
LTGVFSELEVLAAIFASAVHDVDHPGFTNQYLINSNSELAIMYNDESVLEQHHLAVAFKL
LQDSNCDFLVGLTKKQRQLFRKISIEMVYTSLVYGLRKMFGSFVTVSFLSLNFTLM
>A0A2G8XXK3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii COUG|TrEMBL
MRLREHSLLLCVDAMSRDSPVASPAHSGVFGPSADAEVSEVFSLPSLSAIPGAASASSLS
RENSLISSQRASPSVSPPAGSPLWRLVRRCGQGEGERENVERCRLRERREECGAARRGPP
ASAATSDCSCPSAGDRRRVQSRRRRARTFQGRSFCGNHVSTEAEREGETEGEEETEGEEG
REEYDSKRRGRLARRLGRRFVIAAAERGRKREGEETIVLRGNQGECWQEAQRTADSPDCS
SSSVCCFGGSCSTASQCCACMRLASVSCLSPRSSFSTFHCSLPAVSSASAAFVCPREPPG
SDSNSSLSCASSRGFSPSSPKATVSSSRPSSSSASPLRSSLSAPSGLFPVGSGCSSDVCV
SVPLPALFRGCRVHSSAPSSRTEQGTALLTGAPPSANELEAASAMANPTNSSRFSRVKTV
SFATLSECGSSHISRRSDSASEPEAEREKPGLCSMRVARRESSPAARSPGRQSERRGTDS
SCTSLPQRSDRAGRDRVGSRGSAEQRSSTSSRRVSDHSRAEAGLWSAGPGDSGASLEPDL
ESRSAFLRRCRARVAAARRKVCQAFQSLAEHDLVFRMKEDLAQMRHESSLRSVFADACRE
RSGVEMSERTRLSVGGGTGRHLSVGTSTHKEGSTHKEGSEKERIRDGGSASPSTHLSRSG
SGDVILRRFPLKFVDRGLEDLFADNINRWMATRLLLMGVLSLVVTSVMWPLMAWSFNLLD
AFNHSEPLGILFHINMAVTVFVAVLFIVTKRCRHLAEHAELIADGGTFLVVTIWGIWNTT
ASYILEHSYVQDVIGSAYPMHPADAPISLEKTSAWSTSLEASSAVAYLYGLLLIVQLDVV
YPS
>A0A654D9H7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sphingobacterium multivorum|TrEMBL
MKQIGLKIKQEWKFLSIFVICSLPGLFSMAQSNTPVLRIGIMADMQYADKTDHGSRFYHN
SLMKVDTAVDFFNRNKVDFSLILGDLVDEGPKDLPVLLEHLSPLKKTTYCLLGNHDYVNV
SKPDLLHTTFGMPAKYYALTKGKWRFVFLNTNALSEYATTLNSADQREWKTLMDSL
>A9GB16|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sorangium cellulosum (strain So ce56)|TrEMBL
MELRVIGCHGGETPRHRTCAFVVDDILAIDAGSLTSGLEVKDQARLEACLVSHAHLDHIR
DLATIADNRCQLGCPPLVIAGTRETLRTLKKHFFNNVLWPDFAVIPSAGQPTIQYLELKP
ERPTPVAGRLVRAVHVTHTIDASAFVIEGDGGAIAYSGDTGPTERLWEVLNQQQDLRALL
MEVSFPNREQRLATVSGHHTPQTLALELQKFRAPRDLPTMLYHIKPVFQAEVERECAALK
GLNLEVLQLMDHFVL
>A0A5P3A1J1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodobacteraceae bacterium|TrEMBL
MIIAHISDLHIAAGAPETALLRPDTNARARALVAHLAACLPAIDLVAISGDLCDTGTPAD
YALLREILSVLPMPFVIIPGNHDRRAPLRAAFADLPFEDATALHYEYRVPGLRMLAVDCI
VPGEPRGRLGPRDLAWLGAKLSEETQGATFVMLHHPPCQTRMGMADAAILTEGAEALRAL
LDGAPNPVTILCGHMHRPFEARFGKTPVHAATSTAFEFDLVPDAATEPGPTDAPYGYQLH
FLTAPAGHVVHRVLPAL
>A0A1V4I8H4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|[Clostridium] thermoalcaliphilum|TrEMBL
MALYAIGDLHFGKAVNKPMDIFGDNWQDHREKIIKHWSESVNDNDTVLVVGDISWGINLK
EAMPDLEDIGNLPGKKILVKGNHDYWWSTVSKLNKLFDNMKFLQNNYYTYENYAICGTRG
WLCPNETKFDEEDEKIYNREVQRLKLSLDAAKKDGFEDIIVITHYPPTNDRLDESNFTKM
YEEYKVKKVIYGHLHGKESFKHGLIGERNNVEYSLASCDYTDFKLIQIMK
>A0A1V4I6A7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|[Clostridium] thermoalcaliphilum|TrEMBL
MEYDRLILDGDDSIIRTLFFTDVHITGRNPRSRKDNFLDTVLDKLSQLSSIEKERNCDFV
LFGGDLFDNPSVSDAVSGRCAKVLRTFKKLIGVAGNHDLFGNNIDNIKSTRLGLFEKAGL
IDLLYKGERLLVKKNDLTLQITGTPSHFGIDEDDIEGDYVVSDVHKDAHKAIHIIHGMLM
EKSFNPHMKVVTFDDIIGTRADLTLSGHYHRGFKPVNIDGKYFANPGSLSRVSADVSEMQ
RKVGALYIEVSKDNINLEFIPLRQKSGDEILDRSFIEKGKYREVKMEEFLREIRSTSDIE
SADIKSIVRKIATNENLSKDVLEYALTKLSQAEENLSKE
>A0A447LJ14|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Atlantibacter hermannii|TrEMBL
MESLLNLPVADKASVRILQITDTHLFAEKSETLLGINTWSSYQAVLDAIAAQQRSCDLIV
ATGDLAQDHSSEAYQHFAQGIAAFAAPCVWLPGNHDFQPAMFSALQDAGISPAKRVFCGD
KWQILLLDSQVFGVPHGELSEYQLEWLEAKLADVPERHTLLLLHHHPFAGGMQLARPTQF
T
>A0A086PN15|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii MAS|TrEMBL
MGRLRSAATRMATRAGRRNEADGALEEGNDLEGRPGAGEASTPHNRFGLVGLSEPRDDLR
RPLDAEPFVPKHSAGEFPGSCKFQGRSARLSLNSTVLGEDCPMRLRTDGASPDMKVEEGE
SGTGVPLPAVSRLCTSPRVLWGLNSGLSLLAGSVLQGAGTEKAGRNLSTKVSFEATRKDS
RRDSMRLAFSKQGANGEAGRLQSVAVREEPERLVSTKVRDVCTRNSPHESSSSRRAVTIR
VDGSVVDSVELGCRTWNGCETPTERGVKERKKERKKEREMEEKEEEEMLDTDTPPHLRGR
GTLEALYLKWSKHSVYKFFSEEDRKYFDMATTGIPCYFSSKNLERSYALYRCPALSGYLL
LFHTAWIICTWTIYCLCVLTRPAVTSSRRMVAPFVVSWMISALSIFVVFLWRQTGGVAVE
RFNRKEKELRKAEEGAVPMYEAYHWRPCFTEDFGTASIGLATITPVALAAAVAVWIGLDP
YIINDYGESSSRLAPPLLDTSFGLAGFVASQGYIAFSVLFLTVSVICSGIRLRKMLYVAV
GNMISVLTALISFAFAYKDYTL
>V5BLE2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii (strain ATCC 50861 / VEG)|TrEMBL
MNASSKSMRIGFPNGSPGVGDPGMPSPVLPLCQTASHALGNARSQASEGRTDGASDRSIS
ELEKESCQRGHRLEAREASEILAAESAQEEHRSCARKPRASRVEVDTLAESPERPSQAYV
PTESLGLGPRRTVPLCSAGSSASAGSWISSGDSVREETRQIRGRDAANKCSTAELSVSVE
RSCGHHEGTDTATQCVAARPEALCAAFLPAPSPGVSVDSAAAAVGPHCAAEVPVGADRRR
RLFAAPFSALPQTDACSRGSATPPSLFSRQPFDTVRSSSSLQDGGNAWTRLLDGCSAHPT
SSSSSVSPPVLGSIRTLQQSLPSSDDDTTSARTDTSLTPAKQVWLLPLHGHSLSQSSSSS
FREFRVTLGSLTGFRSSDSRTSASGSERRRSKSRGKPQGRSGSLGRDNRRKSELSGRDES
LSWIARRWWTRDEDSRWSDSRVRGSVALRAESTSDSRCENNSCATWLCRVVRRLPVAPAQ
TFCDEDEKRYTEGVLRFSRRRTIPVAVAVVIVSFLYTVPFVLHALQEFVQTPSADRKVFV
FFSSRAPPRSPVAAGAAHDAQLDFSAADSALQDVGGKDAFFVVASLVFWLLSLASVLVFA
FFAVFGALFVRIEKILCVLTAVNFSALALAECFQALRISSCPPSLFPEQAAAEGGSDADR
CAQVHSGLTPELLIIQTFFLIVLDFAFCVRLRISQWLHLCAVSLLLSLAFVYSILLPLPA
YLIASLWGQAVIGGFVLGSLHLAALTLETERRRVFLHFEVAKARVAELQERAQTDKHHGK
VAVFGLIHTLKQMDACMNELQNLAPEAADVLFQLDALRVQCLDIATSSENFYAVNMNALP
TDVRDLLQLETRNAFDGTTFRDTQVLLRDSLSPRKGVLLDLSLGPACGGVSRERRASCSA
AVSSTSSRESDRREAIARDPDLTETERRDAERRGMERKATDDRQKKARFLVVPQLVEHEL
LCHVGILWSLDLFKLDKECNGNALLHVGYQLLAPLLAAGYLTCSREVVLDFLYSLQCLYI
DTPYHNQLHAASVAHLAFSICHFLDLFAPLENAPGDAAASQPVFAQYLSLAIAALGHDAG
HPGRSNAFLVQTSSTLSVVYNDRSILENYHACLTFYTLSHRKSNIFRGKTVTQYRDVRKK
AIELILSTDMSLHFEFLTRVAARRENPDFNFVDREEDRALVLSLAIKVADLGHCALDWEA
HTLWSARLKEEFLAQGDEELRLGLPVSPLCDRTQQGQLARSQANFIEFLFLPLAQHLAAV
APDDRFEATVVTRARQNISMWEGAQDEVDQASAK
>A0A4W6DN78|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lates calcarifer|TrEMBL
LLTCAVCVCVVRLKGVLEQMDRGVVDLQELRRNLELAAAMLDAVYTDETRRLLDTEDELS
DLQAESVPSEVRDWLACTFSRKMGVAKRRPEEKPRFRSIVHAVQAGIFVERMYRRTSNMA
GLTYPPTALTEVDQWSFDVFSFHEATGDHALKFLVYDLLTRYDLINRFRIPVQALVQFVE
ALENGYSKHRNPYHNLIHAADVTQTAHFLMLHTGLMHWLSELEILAMVFAAAIHDFEHTG
TTNNFHIHTRSEVAILYNDRSVLENHHVSAAYRLMAEEDMNILVNLNKDDWRELRSLVIE
MVMSTDMSCHFQQIKTMRNALTQTHGIDKVKVLSLMLHAADISHPAKAWPLHYRWTHSLM
EEFFRQVLCCSGIHEAVFRAVLHI
>A0A086L0T0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii FOU|TrEMBL
MNASSKSMRIGFPNGSPGVGDPGMPSPVLPLCQTASHALGNARSQASEGRTDGASDRSIS
ELEKESCQRGHRLEAREASEILAAESAQEEHRSCARKPRASRVEVDTLAESPERPSQAYV
PTESLGLGPRRTVPLCSAGSSASAGSWISSGDSVREETRQIRGRDAANKCSTAELSVSVE
RSCGHHEGTDTATQCVAARPEALCAAFLPAPSPGVSVDSAAAAVGPHCAAEVPVGADRRR
RLFAAPFSALPQTDACSRGSATPPSLFSRQPFDTVRSSSSLRDGGNAWTRLLDGCSAHPT
SSSSSVSPPVLGSIRTLQQSLPSSDDDTTSARTDTSLTPAKQVWLLPLHGHSLSQSSSSS
FREFRVTLGSLTGFRSSDSRTSASGSERRRSKSRGKPQGRSGSLGRDNRRKSELSGRDES
LSWIARRWWTRDEDSRWSDSRVRGSVALRAESTSDSRCENNSCATWLCRVVRRLPVAPAQ
TFCDEDEKRYTEGVLRFSRRRTIPVAVAVVIVSFLYTVPFVLHALQEFVQTPSADRKVFV
FFSSRAPPRSPVAAGAAHDAQLDVSAADSALQDVGGKDAFFVVASLVFWLLSLASVLVFA
FFAVFGALFVRIEKILCVLTAVNFSALALAECFQALRISSCPPSLFPEQAAAEGGSDADR
CAQVHSGLTPELLIIQTFFLIVLDFAFCVRLRISQWLHLCAVSLLLSLAFVYSILLPLPA
YLIASLWGQAVIGGFVLGSLHLAALTLETERRRVFLHFEVAKARVAELQERAQTDKHHGK
VAVFGLIHTLKQMDACMNELQNLAPEAADVLFQLDALRVQCLDIATSSENFYAVNMNALP
TDVRDLLQLETRNAFDGTTFRDTQVLLRDSLSP
>A0A238H7L7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Burkholderia singularis|TrEMBL
MPIADCRLPTMTMKLESVPITLSRCAKTFHGTRVLEPLDLTIRAGETLVLLGPSGCGKTT
TLRLIAGLDIPDAGGAIVFGNEDVTARPIDKRGVGMVFQNYALFPNLSVRGNVGYGLKIR
KMPPAVLRARVDELLAMMRLEAHADKPVDALSGGQRQRVALARALAVRPRVLLLDEPLTA
LDAQLRDTLRREMNALLRALGVTTVYVTHDQAEAMELADRIVVMSAGRIEQIGTPRDIYY
RPANRAVARFIGTLNRLEGAWRDGALVTTGGVIAAAVPASELFFRPEDARIVAPDAAALR
GRIAHCAFLGERTRVTVEHAAPDALVVDMPGRIDFACGTAVGIEIAPEGLLALG
>A0A1R4HGL0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Crenothrix polyspora|TrEMBL
MPEITGCTTLLHVTDTHILAAPEATLLGVNTAHYFQTVLKQAFTNHHVDLVLLTGDLAQD
PCVASYQFIYDALAIYNTPSLCLPGNHDDYPLMQQVFNTESISCRKQVLIKNWQCLSLNS
QIIGANGGYLAEEELEFLDTCLAAHPQHYTLLAMHHHCVKTQSIWMDTMIIANRQQLFDV
VSHHPQLKAIIHGHIHQNLDAKIANIHVLGTPSTCFQFKPKAHEFELDDTSPGYRIIRLY
DDGQITSEVMRLSTPVQGLQLHTHGY
>A0A0B3SE82|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mameliella alba|TrEMBL
MKFIHMSDIHLGVPGMLIEGIDPHERLARAFGHIAEHHSDAVRLVITGDLAHWADPEAYA
ALKQALRVLPIPVRLMVGNHDDRTAFLEQFPEHPRDAAGFINHAEDLPEGRFIYCDTVQP
QSHAGHFCEVRLDWLRAQLEGCARAFLFFHHNPLHLGDPSSDMLSLNDRDQAGLRPLLKA
HRDKIVHIFFGHVHEPLSGTLAGIPFSGVASTVHQVIPNLSPSKLSGMGPLEPSYRVVLM
RGEDVVVHQIPFAWDGEVIWHGNDWEDWAREA
>A0A8C8GKE8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oncorhynchus tshawytscha|TrEMBL
MLLSILSISHHYILRCLVKQLDKGEVNVVDLRKNIEYAASVLEAVYIDETRRLLDTEDEL
SDIQTDSVPMEVRDWLASTFTRKMGVVRRRPEEKPRFKSIVHAVQAGIFVERMYRRTSNM
AGLTYPPAAIAALKDVDNWSFDVFVLHEASSEHALKFLVYELLTRYDLINRFRIPVSSLV
SFVEALELGYSKHRNPYHNLIHAADVTQTAHYLMLHTGIIYPDFEHTGTTNNFHIQTRSE
VAILYNDRSVLENHHVSAAYRLMQEDEMNILVNLSKDDWRELRTLVIEMVMSTDMSCHFQ
QIKSMRNALQQPEGVDKAKALSLMLHAADISHPAKAWKLHYRWTQALMEEFFRQGDKEVE
LGLPFSPLCDRKATMIAQSQIGFIDFIVEPTFSVLVDTTEKIITPLIEDTLKSHDTGVRR
SSLTGIDLKRVRHTLAEVIQHNKDRWKELSVQGIVVFLLLLFFIFFFLVFFSLLNTFPSF
SVMFFTLS
>A0A3R7KYN7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Trypanosoma rangeli|TrEMBL
MSEIPGLPVQKGRSDGRSDSCATCGNKFSPPTAKSNCPCCEKLCCSDCVQAECAIVAGSA
SSKVCIDCFSMLQSNRHTGPVESSPSPEFYAASVSPPRSLTPANGRERSAAAHARASGDE
RTQDALAVDGECASLSVFQQYVGDPKHSEFLQTKSDSLLRHLRERELELQSLRVERDRAI
APIAPGEKCIWNKTEVQQTSEENAKELREQLDSAQLRMGAMETELKKALDRAKSSEATVQ
LLQQRIGRYEDEVARLQQSQKGLETAPGSVHKDTLWTRKLHPSIVQDTVLTVVTPKSCEA
SGLDVNLRDWKFDSFEVASRVPSVLQSVAMNVALAWNLFSSHDEFQRWVMLVAAVENNYR
PNAYHNAIHAADALQGVFYLVTSATPLMEHMTPLELKAAAFAALVHDVRHPGRTSGFLAA
VQDPVSYKYSGSGSLEQLHVATAFELLTVPEFDFTSSMDNASFLEFKNIVTHLILHTELR
LHHDIISKLGAKVGAGRLDCTRKEDRLDALSFILHAADIGAPSRGVAIARRWLVVLQEFA
DQAEDERRRGLPVTPGFDTPSLVESSQIAFLDFFVIPTFDLLHQLFSSIEEPLHNLRKLR
EVYAAKAGVKTPFPPPVDYRGQEEKSQRLEAGLAEHRSQGREFYRLLEELKTAGINLKRK
SAALRTKEEELIKRSCLQGQGEGRWKFDPAKTGDELQTEKEMRGPQQVYIDPLRNETVEA
TAGRDGTRDQVGGWSETIEARERKLREREAALMMSARSMDIREKKLAAFSEKLADIAERL
HAEQKRVRETENPAVALPHRESLLVATGDADINMARPSLAQHEAEERLAKKYNEVDELLL
MVRAMRIECVAISGTDVRQRALSATLAEREAAIAEAVELSRQRRRQAEEGRGLRPTSMQL
SRLESAIFQLTAAITLLAE
>A0A315XLU8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Methanobrevibacter thaueri|TrEMBL
MTLIAHISDLHVSKSEFDEGILMDAITEINNLEPDMIILTGDITNNGYLVEFEQAKKYLE
MFEAPLFAIPGNHDSRNIGYQTFEEIIGERSWKLTMDEEFTVIGLDSSSPDESRGHIGNP
QHMWLEHQLDECVINENFTIVALHHHVVPIPQTGRERNVLSDAGDILKTLTTHEVDLVLS
GHKHVSNIWKINDTLIVNAGSLCSTKLRGRNKNSYNVYNITDTEIEIFLNEVNGEKFLFG
KYPRNEL
>A0A425I986|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii CAST|TrEMBL
MNASSKSMRIGFPNGSPGVGDPGMPSPVLPLCQTASHALGNARSQASEGRTDGASDRSIS
ELEKESCQRGHRLEAREASEILAAESAQEEHRSCARKPRASRVEVDTLAESPERPSQAYV
PTESLGLGPRRTVPLCSAGSSASAGSWISSGDSVREETRQIRGRDAANKCSTAELSVSVE
RSCGHHEGTDTATQCVAARPEALCAAFLPAPSPGVSVDSAAAAVGPHCAAEVPVGADRRR
RLFAAPFSALPQTDACSRGSATPPSLFSRQPFDTVRSSSSLQDGGNAWTRLLDGCSAHPT
SSSSSVSPPVLGSIRTLQQSLPSSDDDTTSARTDTSLTPAKQVWLLPLHGHSLSQSSSSS
FREFRVTLGSLTGFRSSDSRTSASGSERRRSKSRGKPQGRSGSLGRDNRRKSELSGRDES
LSWIARRWWTRDEDSRWSDSRVRGSVALRAESTSDSRCENNSCATWLCRVVRRLPVAPAQ
TFCDEDEKRYTEGVLRFSRRRTIPVAVAVVIVSFLYTVPFVLHALQEFVQTPSADRKVFV
FFSSRAPPRSPVAAGAAHDAQLDFSAADSALQDVGGKDAFFVVASLVFWLLSLASVLVFA
FFAVFGALFVRIEKILCVLTAVNFSALALAECFQALRISSCPPSLFPEQAAAEGGSDADR
CAQVHSGLTPELLIIQTFFLIVLDFAFCVRLRISQWLHLCAVSLLLSLAFVYSILLPLPA
YLIASLWGQAVIGGFVLGSLHLAALTLETERRRVFLHFEVAKARVAELQERAQTDKHHGK
VAVFGLIHTLKQMDACMNELQNLAPEAADVLFQLDALRVQCLDIATSSENFYAVNMNALP
TDVRDLLQLETRNAFDGTTFRDTQVLLRDSLSP
>A0A163ERG2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Prochlorococcus sp. MIT 1306|TrEMBL
MRLVQLSDPHLVAFNDQLVRGHNPLLNLQCALQKACSHSPDLLLITGDLCHDESWCGYVL
LRDELQSLNPSIKVAVLPGNHDNPLFIKAALGRHAFTAPADLNIDGVRFILLSSHVSGQI
AGQLGQSQLQWLDSRLSDIEQSCRPLVVALHHPPLPIGSSWLDPIGLLDGEALIKLLTPV
EELCAVVFGHIHQHWQEVLPGRKDVLLLGCPSTLCSFEAVQPCPFGREDEPGGRLIELDE
SGTLFEMILRWSNPYHGDVTR
>S3K8S2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microcystis aeruginosa SPC777|TrEMBL
MNFRFAILSDPHIALPTTILNHSNRFHLVEVSIPALKIVLDHLITLNLDFLLIAGDLTQD
GEPENHRWLADCLATLPFPVYVVPGNHDVLSLTATENQIGLADFPFYYQQFGYSNPEQIY
YQKEILPGVQLIGLNSNQFDEQGGQIGSLDAEQLHWLKQTLPSLKNDLVMVMIHHNVIEH
LPGQSNHELGKRYMLANAVELLDILQENGVKLLITGHLHVQDLAFTRGIYEITTGSLVSY
PHPYRVLEYCENTVELAIESFHLQNIPGWENLPAISRQWLGDRSYPFMMRLLTCHPLNLP
VSLAEELAPKLRNFWADVAKGDTIFDFSDFPPLARRYFYAFSAVDPLGNPHFIDNQAVIS
FKHQFSYRRSNLLVEMGE
>A0A653W8I7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. 9Ag|TrEMBL
MAAAPLTVENDSVLLVQLTDSHLFAEAGGKLLGMDTAESLQRVVDLVLDEQPRIDLMLAT
GDLSQDGSLASYKRFRQLSERIDAPVRWCPGNHDELAPMQEATRGSDMMAPVLDIGAWRV
VMLDTLVPGAVFGMLREEQLALLERTLQQASDRPHLVCLHHHPVSIGSRWMDSIGLHNRE
ALFEVLDRFSCVKALLWGHIHQAFDSERRGVRLLATPSTGVQFAPGSEDFQVDTLAPGYR
WLRLYADGSLDTGISRVVGIDFVVDYCVKGY
>A0A377KYN7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Enterococcus casseliflavus|TrEMBL
MNVLHISDIHFRESYLPCEEGYQGMLAAMQNPLIPLEECIQDAKARAAIDLVVISGDLTE
DGAPADYASLKQYLEKAFGSVPIVVTLGNHDIKRHFRQGWQGKSVETASDTPFNQVYETE
TLAIVTFDNSCYGYADGIVDERQFEWLQATLAQLKEKKIVFVTHHHLLPDQASTRAWAGA
NRLVALLQQYQISCILSGHTHHAFTGTIAGIPYYTVASMSFVGEDEGDGMVRFEERYGYN
LYRFEEGALVHQSSENYRPNRVLMRVNMQG
>A0A031HYU1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Delftia sp. RIT313|TrEMBL
MPTPESHRTSRTSMTTFLAQLTDLHIREPGRLTYRRIDTAQYLERTVQSVLALPQQPHAV
VITGDLTDFGRPAEYAHLRSLLAPLGTLPTYLLPGNHDDRDALRTAFPEHTWLRSEGFIQ
YAVDIGDLRLIALDTVVPGHSEGALCEERLQWLELQLTASEGRPVVIAMHHPPFETLIGH
MDKIGLLQGAQALEDLARRHPNVQRVICGHLHRSIQVAFGGTVAMTSPAPAHQVCLDLAP
DAASAWTLEPPGFMLHALPHGGRLVSHAVASGQFDGPHPFWDADGRLID
>A0A5K6CV51|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acinetobacter baumannii (strain AB307-0294)|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIQQILKQHPEADAIIHT
GDLAQAPTPITYKRYINFMQTLGLPFFQTLGNHDNVDHFPLHNENHQQPVVVGLGNWRVI
MLNSAVKGKVDGHLSSEQLENLANLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFQNVKALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLNNDGSFETKVFRLENFKTRINTDISGY
>A0A6N2T838|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Anaerostipes caccae|TrEMBL
MRIIQISDFHLRGDGKLSFQKADTIAALNQTIEYFSKLKPYELPEFFVVTGDLADGGTQE
GYEIIRDGLDKLPRPYFVVPGNHDKRDFFLRMFPENAPVEDDIKPYICYTLDDGLIRAII
IDTMIPDCHYGGLTDEVAEWLEKKIIEYPNKPTLVFTHHPPFTTGLAAMDEGFAQADRLA
AILKKHKNVRLCCGHMHTGIFTSWQGVSCVTCPPIAMQMEVDFRTKDGPDVTQEELADHF
KGGGDRFFLGNPGYLIHDLQNDMVNTHYMIIPTGADYSGPWPFKYYEGEGH
>A0A6J8AA99|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mytilus coruscus|TrEMBL
MSPLAELYSTSTLEHHHFDQCIMILSTKGNDILSSLKPDEYERVIQLLESAILATDLALY
FKFRGEFFHLVEDKQADWSKESDRGLLRSMMMTASDVSAITKPWEVQRKVAELIANEFFE
QGDLEKIQLKITPMDMMNREKKEELPRMQVGFIDAICMPVYQAIAKVSPKLSPLLDGCAK
NRDNWLQEAQSKHVQDQCGRENESKDLCESEIKDRKRSNGHDEKMDVS
>Q16713|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Homo sapiens|TrEMBL
TVFWMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAA
AIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDEMNIFINLTKDEF
VELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKSKALSLLLHAADISHPTKQWLV
HSRW
>A0A1N7RUT3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Paraburkholderia ribeironis|TrEMBL
MLLAQISDLHIKRPGALAYRRVDTAAYLARCIAALNALEPRPDAVIMTGDLVDQGDPAQY
EHLKTLLAPLAIPYFLLVGNHDERHALRAAFPERAELRSGGEFVQYAVDVGALRVIALDS
VVPGESGGTLCEARLAWLAAQLDATQGKPTVVALHHPPFACGIGHMDDMRLDAAASDRLA
ALIARHPNVERVICGHVHRPMFVRFAGTIACAVPAPAHQVALDLREHAPSEFVMEPPAYA
LHRYDPATGIVTHHAYVDAADGPYPFYEPAGELID
>A0A0P8WZX9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oxobacter pfennigii|TrEMBL
MKIYAISDLHLSKSDPKPMNIFGNAWTDHWHKIRYDWRNKVNTDDVVLIPGDISWAITLE
GALPDLLEIGELPGKKILIKGNHDYWWESPTKIRNILSHNMFIIQNDFIDIGEYNVCGTR
GWLLPEDDRFKKDDEKIYKRELLRLEMSLNKAVKASDKPIIVMIHYPPVNEKNSISEFVH
IMKRFDVLACVYGHLHGESLKNTMEGSIEGIDFYNVSCDYLDFSLKGITPVKRNRII
>A0A3R7JUZ6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Trypanosoma conorhini|TrEMBL
TGEVTVFTASDRETFRVFXLFAGISINNSHLLEFAVNAGREMMELNENRALAGGRRASVR
NIKRPLAITDRERDAVREIELGHLDITSVEFDLFYVRENMEEPLDAAAAVAYRLILGTGL
PQKFRCHDDTLLNFILQCRKKYRSVPYHNFYHVVDVCQTVYTFLYKGAACEKLTELDCFV
LLVTALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPDSDVF
EGLDSADRALAYRAMIDCVLATDMAKHGAALDGFLELVAHPDPNLVNFRQMTMEILLKAG
DVSNVTKPFDISRLWAMAVTEEFYRQGDMEKEKGVEVLPMFDRSKNTELAKGQIGFIDFV
VGPFFKKIVEACLTGMQWTVDRVNSNRAQWERVLEAR
>A0A7W8NVL6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Herbaspirillum sp. SJZ102|TrEMBL
MRTTSLLVDHDILIDAGTGVGDLPLERLAAIDHVFITHAHLDHIACLPLMVDSVGELRER
PVTMYATRETLDIIRRHIFNWQIWPDFSQIPTPDNPFLRFAAIEVGQAVTLGMRSITPLP
ATHTVPAVGYHLHNQASGASLAFSGDTCICDPLWEALNAVGDLRYLIIEAAFADRERELA
LLSKHLCPSLLLAELAKLRARPEVLVTHAKPSQQEQIAREIAAGNSPHQPRMLAPGVILA
F
>A0A0D6T1L3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. FeS53a|TrEMBL
MSSANRHAAAPSVLLVQLSDSHLFAEEEGRLLGMNTHDSLSRVIDQVLEEQPAIDLVLAT
GDLSQDGSPESYVHFRDLCARIPAPCRWFPGNHDEVQVMEQVCRDSDLLQPVIDFPAWRV
VLLDSTIGGAVPGHFPPAQLALLEQALREAGDRHVLVSFHHHPVPIGCRWMDPIGIRNPD
ALFEVLARFSNVRGVLWGHVHQEFDQLRDGVRLLASPSTCVQFAPGSEEFQVGGEAPGYR
WLRLHGDGRLETGVSRVTGIDFEVDYSVKGY
>A0A1F2Q0Y9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodococcus erythropolis|TrEMBL
MSVRSAEYPRPKHFLVHLSDTHLVAQGELYDAVDASTRLREVLSGIVASGARPDALIFTG
DLTDQGHPDAYAELKAIVEPVAAEIDAQVIWAMGNHDDRSTFRSLLLGEDATDHPVDNVY
DLDGLRVITLDSSVPGHHYGEISDRQLDWLRSELAVPAPDGTILALHHPPVPCIQDLAVL
VELRDQSRLADVLRGSDVRAILAGHLHYSTTATFAGIPVSVASSTCYTQDLNVEVGGQRG
RDGAQGCNLVHVYDETIVHSVVPLGAHVTVGEPVDADEGARRLSAAGIRILESEKAGRSI
V
>A0A3S4WAN8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Actinobacillus equuli|TrEMBL
MNGFYSLGKKEPVVRLLQITDPHLFSAEHETLLGVNTTDSFQAVLEQIRQTSFNYDLVLA
TGDLIQDHNPEAYHRFAEMVKQLAKPVFWLEGNHDRQPQMSLYLGKHPHIQSEKQILAGS
HWQILLLNSQVANAPSGNLSFGQLAWLNSKLAEYPDRYTLVVLHHNILPTNSAWLDQHCL
KIVTLWRKY
>A0A1Q2HQQ4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sedimentisphaera cyanobacteriorum|TrEMBL
MSSKEIDRRSFLGSAGALAAGIMLNSGTPAKAAQNGKAGSKQGSRICHLTDIHITPFRDA
PETFEKAIEQINSLNPKPSLIVTGGDNIMDSFSTPEEQVKRQYEVLDKLMAKTDIPVKYC
LGNHDLWGWNKSKSKTTGDEAKWGAKWPIRHYGLPGEYYTFNHSGWKFIILNTVQPDPND
KNGYIGGIGDKQFAWLENVLAGMPLDMPAAIVSHIPLLTISNFELMDSGRNLPKINPGWI
CYDGPKAAKLFSRYKNVKLCLSGHMHRQDRIDYMDVSYICDGAVSGGWWRGPHRGCQAGF
GLLDLNSNGSFKHEYIEYL
>A0A1R4JNY8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudoalteromonas sp. JB197|TrEMBL
MAWFDDTYTFNKPSLRIAHVTDCHLFADRNAEYFGVNTATYFQQALEHMALQQLDAVVFG
GDLTQDHSVESYLLFSELISNSTLTCPVFWLPGNHDEIALLEQISGGQIKAAKRLVANNL
TNSLTNNASTDIELLLINSKGLTPAGWVTSEHLNEISDCLAQPVSKQLVFCHHNPLPING
YLDKHMLENGPQLLNTLVNNGNVAALIHGHVHNDYTQCFRELDIYATPASSVQFTKHSKA
WQQQNNGPAYRMLYINSSQGQVHINTDVIWLSA
>A0A0H3DSN8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Edwardsiella tarda (strain FL6-60)|TrEMBL
MAGGALLCGLAMCPAQAAFELVALGSGGGLSGDNLNAYLIRHERDTRYVALDAGTTLPGI
ARALEQGAFPTVSAERAAPWTPQGYVLRELIAAYFISHPHLDHVAGLLLAAPEDSRKPIY
TLADSADTLRNHYFNWKSWPNFSDAGQGQRLGTYRIHSVRPGQRFTLGVSGLSGVVYPLS
HGGETSSMILLEREGEYVAYFGDTGADRVENSQRLDSVWRRLGPLVASRALKGIIIETSF
SDEVPETQLFGHLTPALLNQEMINLSRYSGGTAALAGLPVVISHIKPSLRAGVAAEQQIM
AQLAAGNRSGVAFRHLRQGERTLFAGGDE
>A0A259UJW3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sporomusa acidovorans DSM 3132|TrEMBL
MLGKLLVPAISADSVSVTQEYYRIVLLGDPHLPVRKHVVLDLHKQQKILDAKNRVVYDVN
SWEDVNQIIVLGDIAAQFGNVEEYDYARQYFSQCKKTVSFIAGNHDYMYCDDFSPEGKFV
LADAITREQKLNRFKETLKQPELFFSQKVGQYLLVFLSPDSLDSRHLTQISNPQINWLKN
ELSRNKTTPTIVFFHAPLAGTLYKYNKNVNTPNFISQPKETIKEILDDNLQIIMWVSGHT
HTSAKNSSFVSNVNIFGGHITNIHNTDMDRERIWTNSLYLYPDRVLIKTFNHKDQTWEEN
LERTVYL
>A0A380W7C9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Afipia felis|TrEMBL
MSHDHHDPGRRHALECMIWAGTGVLWTVSGGIPHSVGLIGEASAAQPSGFTFLQMSDSHI
GFDKAANPDALGTLREAVGIVKAMPVKPSFIIHTGDITHLSKAAEFDNAGEVFGETGVKI
HYVPGEHDIIDEDRGKAYLDRYGKGTQGAGWYSFDDHGVHFIGLVNVVDLQGGGLGNLGA
EQLAWLQSDLRDRSNDTPIVVFAHIPLQVVYREWGWGTEDGMRVLEMLKRFGSVTVLNGH
IHQLLQKVEGNVTFHTAMSTAFPQPAPGAAPSPGPMRVPPEQLRSMLGLSSINVVQGEKS
LAFIDRTLAS
>A0A160TEZ4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MLNSIRKQHPQFDAFLVTGDLTQDGSEKSYQHLHDVMSTFQRPAFWLRGNHDEPSAMSKV
AQGTEHLQRVIRNEHWQIIMLNSQVEGAVFGELAGEELEFLDYTLTEAPGLHTLVCLHHH
PVSMNCAWIDPIGLRNSHEFMQLLGRHDNVRGVAWGHVHQALEGVQDGIRLMATPSTCIQ
FEPNSDDFALDDQNPGYRWFELHADGKFDTGVERVKGVHFEVDHSQTGY
>B6AGA7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cryptosporidium muris (strain RN66)|TrEMBL
MARNNGNMTVELMENLGSAEEGGSNWEEKLEPCDNLKNSKCTKDRLKDLITPIVSTLKPS
LTNEFLYPFSLTFRSEMLERNFLTGLRKRMETGVFWIGILALILTIIDIILGIYHLQISG
ATRRSLTVYFAVTGTVAGFALLLIASYFMNFLTRNIELLFTFTSIIATILNIISSNLLIE
ISPEVEKSYDPTVHHSRSLVVITFICMLHFLLPTSFLPILLYVTFSIGSYIILVPSILQP
IPNEPVYISTIIYLIIFSLVCIIAKRLNVISAKKDFYNMNLIKTEIQILEKSINQAPKST
VIEGTLAKINKVQLFLRYLNTTKVKGINKKMLHETMSELTAAQVNLSRTEDIYAVDPASI
FMPAQSQINIASSPFSLKSKLTLSKSLSSKPYVMGSSDSRNIRSGNLSPPVTTKSETNLQ
DSISIPINSQTPQGASGLLSPMNFSNDNNIMPDSLRRNTESRMGSGGIPGPSRRRLSMMI
AGVGENSSSLIDPSAERVREYITAEFTKSSVSRREGIYSSRIFGDKEPGLVRDLDITSCI
SDKSPRNNLIGENIIKDTSQKCLSPRDIKISSESSPNKWRMALKEKRKIAQYTTMATAKL
LSLRDSSGTVKNICSKLFNGVENACDFILPEKPSRVKNTLYEDIEKALQLMEVQYGSDWD
LDMWNLKALTYGNCLTVAGLFMIFVIIAEERNSLLRNDTSTLPRGIAAAHPSSITAPSRL
IKDISKFAVFIREVNIRYLNNKYHNELHGTNVCHHTVCLTKATGLWNHLDTVERLAIVIA
ALGHDVGHVGRTSSFLVNSRHMLAINYNDRSVLEMFHASLTFRIIYYYDGGAADFIQSWD
ADVHRDFRRMVIEFILETDMHRHFECVSRFRVRRQASDWDPYGDVQDRLMLARTCLKAAD
IGHGALEWAQHYKWCRAVIEEFFIQGDEEKALALPISPICDRESTDVPKSQVGFLNFVCL
PLFQELCYADVDGGVRKCIGRILENINYWEDMAEAEIQWDSDEAVSLSPNSRNV
>A0A368F646|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ancylostoma caninum|TrEMBL
MSTLELMALYTAAAMHDYDHPGRTNAFLVAAEDKKAILYNDRSVLENHHAAESWRLLQLT
ENNFIETLDPAETKRFRYLVLEYILATDLKQHFEIIMMFNEKSSEMELLNESDRLLMAKM
IIKMADINSPTKPYGLHRQWTDRICQEFYEQGDEERKRGMPITPYMDRTDAQVAKLQDSF
IAHVVSPLALAMNEAGLLPILPGLVEP
>A0A6P9CYN5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pantherophis guttatus|TrEMBL
MGSTDPEGTQKMDSTPLKYPIGGHTEKMWQRLKGILRCLVKQLEKGDVNVAELKKNIEYA
ASVLEAVYIDETRRLLDTEDELSDIQSDSVPLEVRDWLASTFTRKMGMTKRRPEEKPKFR
SIVHAVQAGIFVERMYRRTSTMVGLAYPSEVIATFKDVDKWSFDVFSLNEASGGHSLKFM
MYELFTRYDLLSRFKVRTFLYKYIFKRQRVPGLSCFLTTQACITFIGLSRLSRMKKQMSQ
CSTIHVPKYKINATVITLIAHRELRNLVIEMVLSTDMSGHFQQIKTMRHTLQQTEGIDKV
RAMALILHAADISHPSKLWVLHYRWTKALMEEFFRQGDKEAELGLPFSPLCDRKSTMVAQ
SQIGFIDFIVKPTFALLTDSMEKIIFPLIEEASKSESPTFVTEPSENSTGSTSSDIHKKI
SIKNAACVGGTCSENALAMVDLRSFKDNLFHNIQENKDRWKDLAEKGEPNLSENSEEPLK
EPELSS
>Q88DB0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)|TrEMBL
MSPPDQSRPVHVVQLTDAHLFADPAGSMLGLKTRDSLRHVLAQVRREQPLVDLLLCTGDL
SQDASVASYEAFRELTAPFAVPTRWLPGNHDEAQVMAQVAPELVQAVTDIGAWRVVMLNT
AVQGATHGFLQDDQLAVLEAALKEAGERHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDI
VEGYPQVRALLWGHVHQEWDEVREGRRLLATPSTCIQFAARSEDFQVSEEHPGYRWLRLH
ADGRLETGVERALDFEVQLDFDSPGY
>A0A1C7FGT0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio scophthalmi|TrEMBL
MDMLKTKLAVLVGCLSLGVAINASAAGFETVTLGSKGGIQDGNLTAFMLKSELDDNYVLL
DAGSVVNGLIVSEQKGAFADVKVPEDSKYTKVGYLLKEKIKGYLISHAHLDHVAGMIISS
PDDSHKPIYGLASTNEGLMNNYFNWSAWPNFGNEGNGFKLSKYTYTDLTQYQWQAVKGTT
MQVMAMPLSHSGGESTAFLLKDTQGDVFAYFGDTGPDAVEKSDALNKVWSALTPFVKQGQ
LKGIVIEVSFTNETPDKALFGHLTPNWLMKELTVLESMAGKGSLKGLDVVVSHIKYSLKK
GEDPQVVIKRQLDAANTLGVNFLFPAQGDALTF
>A0A379T558|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salmonella enterica subsp. arizonae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYGALQEAGISPAKHVLIGE
EWQILLLDSQVFGVPHGELSEFQLEWLERKLANAPERQTLLLLHHHPLPAGCSWLDQHCL
RNAAELDSLLAHFPRVKYLLCGHIHQELDLGLERTPSVGVAVNLRTVQTALRELYAGYYR
AGLAYAGAPGERCPGDGSASPAGYPVPARYRFGRILMSTLVYLHGFNSSPRSAKACQLKK
WLSERHPHVEMIVPQLPPYPADAAELLESIVLEHGGAPLGLVGSSLGGYYATWLSQCFVL
PAVVVNPAVRPFELLTDYLGQNENPYTGQQYVLESRHIYDLKVMQIDPLEAPDLIWLLQQ
TGDEVLDYRQAVAYYASCRQTVTEGGNHAFTGFEDYFNQIVDFLGLHSC
>A0A162SPP1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium magnum DSM 2767|TrEMBL
MESSKIRWIHLSDIHYSYQSYDTLAMKNKLYEYLDEITSNEKYDFLIITGDICYRFGKMD
EQMIEKLSSICKIDCKNIYMVPGNHDIKRGSLRGAILDLIKKQNNVRDIYVSSLDKEFYS
ELVKGQNKFWKYHEKHLCSGKYDFKKVHSIIEKENYNIICMNTCFFSGQDGEEGNLVLGL
RNHLEVLGELDKNTNKVNIAIGHHGIDCFHEEERDSIIYNFIDSGVDMYLCGHVHNGNYK
FYNNDLTELPVLTSGSLMLDGYAKATFITGEIELKTKECVVKYHSWINDIQKWDIDNTIG
RRLKNQRLTFDLSRFKKKDEFAIEVSEDEFQEFIIEFIEKSTFYKANEYTNIAKDVYDKF
SNMLCLPTTVSKFDELSKYFYIIDGILLTNELFNEKRLIIDNLITDEYRNCFYTYNDGDK
IIDFIVNSIYNQYKDILNYSKMKFKFFIKILVYWMINFCSIFNEKKVI
>A0A670IDE2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Podarcis muralis|TrEMBL
VPLEVQDWLTVTFARKKEAYSIKPEDQPSIRTISYAVQASVLVKRMFRTPTSASGLAYPE
KVIAAFKDIDKWDFDVFALNETCEGHSLKYLMCDLFNKYDLLRQFKIPITCLISFASALE
VGYSKHQNPYHNVMHATDVTQTVHCIMLHTGMMHWFTDLEILAILFSTSIHDYEHTGTTN
HFHVRTRSEMALLYNDKSVLENHHVSAVYQLMQNEDMNILVNLTNEEWRELRRLVIEMVL
ATDMSNHFQQMKYLKHVLKCLQTDRDKLMSMIVHAADISHPSKPWKLHQQWANALMDEFF
KQGDKEAELGLPISPLCDRGTTNIAETQIGFIDVIVKPIFSLIIEAAEKIVEPLIYEAFE
TGCSSSRDSGYFSGVFGERFTGGKEDKGRMILAAD
>A0A8F4GBI7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella sp. PL-2018|TrEMBL
MLLAQISDTHFRSRGQKLYGFIDVNAANADVVSQLNALQERPDAVVVSGDIVNCGRPEEY
EVARQILGSLNYPLYLIPGNHDDKALFLEYLHPLCPQLGSDAQNMHYAVDDFATRLLFID
SSRAGTSKGWLTEETIKWLEAQLFDGGDKPATVFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQAIISTIPGTVHQVPYFHEDTRPYYDLSPASCLMH
RQVDEQWVSYQHPLTHYAGPWMYDENISCPTEDC
>A0A2X1GN43|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Burkholderia cepacia|TrEMBL
MTVIAQLSDIHVRPHGVLYQDAVDSNVMFSAAVDSLNRIRPEPDLIVISGDLTDEGTEDE
YQKLRELLVELRRPFVVLPGNHDDRGNLRAAFSDHAWLPNEGALSFALDVGELRLVALDT
SVPGLHHGELDAETLAWLDSELTEHRSRTVVIVMHHPPFMTGIPYLDIYGLRNADAFARV
LARHSNVDRILAGHVHRSMQTRLGSVPVLTCPSTTTQIALRVEADAQPASFLEPPAYMLH
RWTGRGQSAVSHLCYVGHFEGPFPFA
>A0A517WPQ1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia aquarii|TrEMBL
MKKQPLFPTESLGRRAFLKNGALILAGLSSNTYGLLSTRAAEASQRGVVRIGLVTDLHYA
DKPAAGTRHYRETIAKLNEVITRFKTERPEFVVFHGDLIDSGKSLEQEKGHLRTVVKAIS
AIPFPKHYVLGNHCVDLLKKVEFLEGVGQNASYYSFDQNGFHFVVLDSCFKSDGTPYGRR
NFKWTDANIPEPELEWLRAELKQTEHPTIVFAHQPLDLKDSDAHAVKNSSVVRKILEESD
KVAAVFQGHSHHNKYSEIGGIHYCTMVAMVEGSGLQNNGYSTLDLFEDGSLVLNGFRKQK
DYRWT
>A0A0M0ELI9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Komagataeibacter europaeus|TrEMBL
MNTITIAHLSDPHLPTEMVPPRLGERLNKRMFSYFSWKGRRRFLHRPEILAHVMTDVAAS
GVDMIAVTGDLTNMGLPGECRQALRWLEQMPAPCTVIPGNHDTLVHDRWHQTVGLWQPWM
GALPFPFVRRVGNVALIGVSSAVPTPWFLATGTVGARQAARLRDILRETARQGLCRIVMI
HHPPVTGLAIRRKALTDIQDFATCIAQEGAEMVLHGHIHTSTLSSLPGPLAPVPVVGIAS
ASARSCDPLRAAGWNHITVTPHATGYRLGVMRHFFMTDATTGASQETIFELPSPSGCFSG
VSTPA
>S7W2B0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Leifsonia rubra CMS 76R|TrEMBL
MHSLLLAHVSDPHASVGGPLYGTVDGIDRLDLVGLSLREMGVNPDAVIVAGDLVQSGHTE
AYTDVAAALTRLEASTGAPVLIVPGNHDHPLAFLTLPQSTGVNRRIAYVGQTRLALLDSS
TGSLGSTQLEWLAGELREPHQDGTVVVLHHPPTPSPLPALAGRELSDADELAAVIAASDV
RMILAGHFHHSLSAQLGSVPISVSPALSYQQDPTAAPESVRGVDSPAYSLVRLTDRGHSV
VSVALRPSEVLFNSHSRHITAISHLN
>G0QZ61|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ichthyophthirius multifiliis (strain G5)|TrEMBL
MSENQQKLNNIQFLQKLSNESENQETSKIIESCGIFLKTIKKFKRKLDNNLKFNERDIDA
FRRRYENTTKQLIPLIHDIKINVIERMIKFDIKQLKNQNFQMHLYTNKELCELSFKIFDY
DATYLDYLSQDQMKKLIKTLCLNYNVVPYHNWTHAFSVFQMFFCCYQNSDINYFFQQKIV
YIAGYLQSIFNLLNKEGLNNLYKIKRKSNICINYAEQGVLENMHCSQLFNIILNDQEINF
FQKFSDQVKIKLKRQYYLQKKYKIQQFKRIVITSILATDIAKHQKLHTKFKKRSTSTLKL
QKIKSEQEKNAASDLDKYLKFNNDNFEDRRFILNIITHACDIGNPCLQFNNYLNWSYLIT
QEFMDQADKEKQNNLPVTTFLIYKDKLTFLNGQLFFVSKNIFFNKQNIYFNVQKKESIVL
PLWEDIAELFKELKEYPEQIKNNLIEIELQRDKIQQQKLNA
>A0A1V5IS87|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Actinobacteria bacterium ADurb.BinA094|TrEMBL
MAELTIAHISDIHAGSPYFVPSMMDRVVVELNELRPDVVLCTGDLTEMGFRPDYVTAKEY
LDRIEAPCVVVPGNHDARNVGYVHFEELIGPRWQTLSLAGVKIVALDSSEPDLDYGQIGR
ANYGFLREEFAQPASFRVFMLHHHVLPIPGTGRERSMALDAGDLLEVLQECNVNLVLSGH
KHVPYAWRLERLFVINAGTCSSLRLRGNTKSCYNVVRIGDDRVRVARKYPFHGEEELIDF
VPSTAAFDKYICRTMEEGA
>A0A060RW53|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Plasmodium reichenowi|TrEMBL
MEIKCDINHNLDVKCSLQNFVRNISLDNEKKVLHVFELKNIRTIYDLIFSVSFFKFSNCM
TDVYSNDSGEDTSIHKLNINWKGHKNVLCANNKLKQDNELPTIVYDKDICNIKNGTLQGK
SSNINDILKSSINTSKNNNNINNNNINNNNNNNHLYNKDEFINNTLKNEEYNNILSNTEL
NKMNPSNNKEENNTTTLLPKHSNVMEINEMNNYYEKKKKECTYNNEYVYFDIYINSDIIN
IFHVNDKDKEKLIKYIYDIIETNDILIMCIYLNLQNVYEKLEKYNILNITLLKNIIEAKK
FEWMKNEIGISLSEFILIINFILKVKKNRIFCSNIFNQYNKNNNKTTKKKKNTKTLCDKI
HQFIEFDNWTFKNIIDNPFFQRLRSLSQLGACQYVYPGATHSRFEHSLGVGFLSAKYFTH
LCNRSNLSPYHGELKRMLRCVQIAGLCHDLGHGPFSHTFESFFMNYKKEDTDHKWNHASM
SLNIAEHIIENLIDQDDVLDVSDIKIIKKLIKGTENNKTFSGIDPIDSLITASFDIICNN
KNGLDADRFDYLQRDATIAPPNGTLPSLNCNRIIGQSAVINGHITYNVKEIHPVWTVYMN
RFSLFKQVYTHRKVRAMELMLCDGFRLADDIFKWSESLNDLDSFLDLTDSSIIYDIKKKA
KVCKYDEKLNHSLNLINSVIYDRNSEYTYKYISEINITEPKLIEYLKDITNEEKIARYAH
GLSPDDIIIDWNYLNYGMGANDPLDSVYFYTSDNEDEAFIAHKEYRGTHPRYFEECNVRL
YCKNKKVAHLAKQAHLNFISSEVFTASSPLHKKQKNC
>A0A1V5RP55|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chloroflexi bacterium ADurb.Bin325|TrEMBL
MAFSFVQITDHHLQESESATVRGFATWVSYRAVLRHIAQHVAGHIDFIVSMGDLVDPAPD
PAYRAVLAALHADPAGATAPGPLRVTAEGLEDMPMYFVPGNHDDLSAMLRVLFPGSPDME
RMNVRFEHRGVRFVCLDWGRDPSAQATPELFEFLAESLADDRPAVILTHHAVAPVGAAWL
DQFLARDVDRFWNIVRGRNVLGVLAGHVHMSTEELVAGVPVYTLRSTGFQFARQDQPATL
LQPPHYRLITIHDGVLTSRLYEVSI
>A0A3N6DYC4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces sp. ADI93-02|TrEMBL
MALLLAQISDLHLDGTERATRRAVRVMDHLRALPRPVDAVLVTGDIADHGAEAEYEEAAR
ILAAPFPVLPCPGNHDVRPAYRKALLGEAPEAGPVNRVHHIAGVAILMCDSTIPGRDEGR
LDERTLAWIDSTLAGLPEGQRALIAFHQPPVELHHPLPDSGMLERPGDLAALLDAHPRVA
AVLTGHAHTAAASVFAGRPLIVGPAITWTLRMPWEGDRPADREQPPGLAFHILGDDGRLT
THYRVVI
>A0A0M7J3E1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Achromobacter aegrifaciens|TrEMBL
MLIAQITDLHMRTPGDKAYGIIDPAAFLAPAVRALNALTPRPDCVLITGDLTDLGRPHEY
QVLRDHLQALEIPYFLLPGNHDDRAQLRAAFPDHGYLQGESPFIQYTIETYPLRMLALDT
VVPMKSHGELCQDRLDWLAARLAEQPERPTLVLMHHPPFLTGIEHMDAIGLLAGAPELER
IVARFPNVERVLCGHLHRTIFQRFGGTIASTCPGTAHQLALELGPRPTLQYIMEPPGYQL
HWWQGKNLVTHHAVIGEYPGPYPFA
>A0A8D2P8U7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Zosterops lateralis melanops|TrEMBL
MSPPCDCPFSRPVPSVSSGCPLGVPSVSPVLAYPLGVFPAVPWVSPAVPWVCPRLSPEKP
KFRSIVHAVQAGIFVERMFRRTYTAVGPSYSSSVLNCLKGLDQWSFDVFSLHRAAEEHSL
RTVVFELFTRHSLNSRFKIPGAFLTSLLEALESGYGKFRNPYHNQVHAADVTQTVHCFLL
RTGMLIEVLAIVFAAAIHDFEHTGTTNSFHIQTKSDTAILYNDRSVLENHHISAVFRLMQ
DEELNIFVNLTKDEFAELRALVIEMVLATDMSCHFQQVKSMKTALQQLERLDKSKVLSLL
LHAADISHPTKQWAVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGES
WGMSPVPVLSPDGDRDGTRTGMSL
>A0A8D9R8S3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Burkholderia mallei FMH|TrEMBL
MPARCRPRTLKDRKIVRQAIKRCNQISHPVAPHISPLLSITYQKRQPARTTLNDRYFP
>A0A3P7J1I0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Strongylus vulgaris|TrEMBL
MFGRICDEDDDLAEVTPETVPDEACITSAIFTAPEPVREWLAATFTRQNAGKKREKPKFK
SVANAIRTGIFFDKLFRKQQSVQCPIPAEIAELLREINSWSFNPFQLNEVSEGHALKFVG
FELFNRYGFMDRFKIPLPALENYLHALELGYSKHNNPYHNVVHAADVTQSSHFMLTQTGL
ANSLGDLELLAVIFGALIHDYEHTGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXEDNFLITLLLMREIQCLRSTFALLYNDRSVLENHHVSACFRLMKDEDKNIFNHLTRDE
YRELRNMVIEIVLATDMSTHFVQIKTMKNMLSLPEGELRNMVIEIVLATDMSTHFVQIKT
MKNMLSLPEGIDKNKALCLIVHACDISHPSKPWLLHERWTEGVLEEFFRQGLSFTAGYIM
QTLKNCGIVSITF
>A0A174WBW4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Phocaeicola vulgatus|TrEMBL
MTNKLLFFVLLALCFSGCDMLETHPYDVHITGERELTNKNIQLIENKMQGKKTIRFAMIS
DTQRWYNSTEDVVKALNARGDIDFVIHGGDQSDFGVTKEFIWMRDIFNKFQMPYVCLLGN
HDCLGTGEDAYRAIYGDPNFAFTAGNVRFICLNTNAMEYDYSEPVPDFNFIENELNNLSP
EIEKTVFAMHVKPFEFVFNNNVAKIFQLYVNQFPKVQFCLYGHEHKFAVDDLFNDGVLYF
QCPCIDKRIYLLFTIKEDGTYDYETVEF
>A0A484PWB8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|plant metagenome|TrEMBL
MLIAQISDLHIRLPGQKAYRVVETDAYLPPVVDALNRLDPRPDCVVITGDLTDFGRPAEY
AHLRHLLAPLQLPFFLLPGNHDDRQALADAFPEHAYLRTDGPFVQYAVEQYPVRILALDT
VVPLKGHGALCAERLQWLETELAREPGRPTLIAMHHPPFKTGIAHMDAIGLLSGAPELAA
LVGRHPNIERIICGHLHRTIYARFGGTVASCCPGTAHQIALDLRPAGPSAFVMEPPGYQL
HTWQGGALTTHSAVLGEFPGPYPFHEEGALIDE
>A0A1A8WE58|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Plasmodium malariae|TrEMBL
MKFDIGNINEFSSVETFLRNISLDKEDKILQTFEVKNIRTIYDLMYTVSFFKFTNCADVC
NDENVEISNALNVKIRSPHKHIFDSNHTANNKFKKENGDRHNSHDTELYNTLSVASNGKC
NNYNTLLKSSVSSAMHIIGAHNKDICNGAYSSGTHNNSYHNNGTHNKDENNIIPNSIHCN
SSEVKEMYDYYEKIKEERKNMKNKVDYVYFDIYINSDVIKIFPITDKDKEKLINFIYEII
ETNDILMMCIYLNLGHLWPKFELYNIRNISLFEKLLSERKEFEWIKNDMGISFYEFVLIV
NFILKVKKKRIFCNNIFNQFNEYNCKNKKIKNTKTICDKIHQFIEFDNWTFKNIIDNPFF
QRLRKLSQLGACQFVYPGATHTRFEHSIGVGFLSSKYFTHLCNRANLSAYHGELNRMLRC
VQIAGLCHDLGHGPFSHTFETFFMNYKKEDTENKWDHASMSLKIAEHIIENLIDQDDMID
VSDIKIIKKLIKGREHNKSTCGLDPIDSLIEASFDIICNNRNGLDADRFDYLQRDSAIAP
PNGTLPSLNCNRIICQSAVINGHITYNVKEIHPVWTVYMNRFSLFKQVYTHRKVRAMELM
LCDGFRLADDIFKWSESLHDLDSFLDLTDSSIIYDIKKRAQKVDCDEKIKNSLKLINSVI
HDRNSEYAYKYISEINISEPKLIKYLKDVTNEDRIARYTHGLSPDDIIIDWNHLNYGVGA
NDPLDSVYFFSSDNENEAFIAHKEYRGTHPRYFEECNVRLYCKNKKVAHLAKEAHLKFIS
NDVFSETSPIYKEILK
>A0A486SIP3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVFSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFID
SSHAGTSKGWLTDETIGWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>W0LWJ7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli|TrEMBL
MSDPVRITNPGAESLGYDSDGHEIMAVDIYVNPPRVDVFHGTPPAWSSFGNKTIWGGNEW
VDDSPTRSDIEKRDKEITAYKNTLSAQQKENENKRTEAGKRLSAAIAAREKDENTLKTLR
AGNADAADITRQEFRLLQAELREYGFRTEIAGYDALRLHTESRMLFADADSLRISPREAR
SLIEQAEKRQKDAQNADKKAADMLAEYERRKGILDTRLSELEKNGGAALAVLDAQQARLL
GQQTRNDRAISEARNKLSSVTESLKTARNALTRAEQQLTQQKNTPDGKTIVSPEKFPGRS
STNHSIVVSGDPRFAGTIKITTSAVIDNRANLNYLLTHSGLDYKRNILNDRNPVVTEDVE
GDKKIYNAEVAEWDKLRQRLLDARNKITSAESAINSARNNVSARTNEQKHANDALNALLK
EKENIRSQLADINQKIAEEKRKRDEINMVKDAIKLTSDFYRTIYDEFGKQASELAKELAS
VSQGKQIKSVDDALNAFDKFRNNLNKKYNIQDRMAISKALEAINQVHMAENFKLFSKAFG
FTGKVIDRYDVAVELQKAVKTDNWRPFFVKLESLAAGRAASAVTAWAFSVMLGTPVGILG
FAIIMAAVSALVNDKFIEQVNKLIGI
>A0A5A4SEK7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella quasipneumoniae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPAEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDAQNMRYAVDDFATRLLFID
SSRAGTSKGWLTDETIGWLEAQLFEGGDKPATLFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A1W6N767|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Levilactobacillus brevis|TrEMBL
MGAWGMNRFTIVHISDIDLTMDDNQRLATQPLQRIFADLEAHQVAADLIVLSGDLLVGGD
QQGYQQLRQYLQLQERRLQVTIQVMLGDRDDREAFNRGYLAVAHQSYYADKQVHQNMDFY
FLDSKWELNKSAGWLDRPQLDWLNKNLHLAPRRRAFIFLHHPLDAPALRDMRYTLLQNNR
ELLAILHGHNIGGIFTGHLHFDANYVVDSVVPVTVTGSATTYINCQNPYQHDVYAGTTYN
VITIQRGVASVITHPLALGQTVIQTIPVNRTGFVKHRPRAIAVRRPIP
>A0A815RHC9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Adineta steineri|TrEMBL
MLSSEHVPSIFFNKSRSIDETNLYDGDIDEGGANKTPYDIIEHDVTTLAKANNLPPPDSF
DALQLGSERLRTIIAALHCNILVRKEDLVRNLDYIANILEAVHQDETRRLMEEDDGALSE
IEPDSVPNEVRDWLAMTFTRSMSTIKRRPSDKPKFKSVAQAIRAGIMVDRYLRRLSIDIK
FKTINEWTFDVFSVNEFTSGQCLRYVGFELMQRYNLPNKLHISITALNNFLEQMESGYSK
YRNPYHNLIHAADVLQTTYQIIYNSGLMNWLNDHELFAMFIAAIVHDFEHTGTSNNFHIQ
SRSDVALIYNDRAVLENHHVSAAFRLMRIDDYNILSEFTPEEFKNFRHLVIEMVLATDMS
SHFA
>V5V7D4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thermosynechococcus sp. NK55a|TrEMBL
MNEPVYLIQLSDLHLFATDEGRLLGLPTAQSLAAVLEATRHHRPNALLLTGDLAQEPVTT
TYERLATAFRDFSCPVYWIPGNHDEPRAMVPALERPPLRGDRQINLGTWQGLLLSSQADG
KVHGELSPETLSWLDATLSHTGDRPTFIALHHPPFETGAPWLDSSRLQNPEHLFAVLDSH
PQVKLVLFGHIHQEFITERQGVTYLGCPSTCIQFLPRAPEFSLEPVGPGFRHLSLYPDGT
FKTYIERVEIPLTLDFSAKGY
>A8J9Z4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chlamydomonas reinhardtii|TrEMBL
EWQYDTWALAEASGGHALSVMGFYLMQREGLVAAFRIQPVKLARLLRALEDGYPADNPYH
NATHAADVLRTLSVLLRGARLTAHYAHGLGLLASYFAAIIHDHGHPGLTGDFLVATSHPL
ALRYNDRSPLESHHAASAFTLLAERPDLDAFAELPKEQRTAFRKQVVDMVLATDMKQHFS
LLTQFTALHKARKASLEPAPSPQDDAERSLTLQIALKAADIGHLAAALPVHCRWLGVLEE
EFFRQGDKEKALGIPISPLFDRAKQGVSKSQVGFFDFVALPL
>T0U0U3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Enterococcus sp. HSIEG1|TrEMBL
MLAAMQNPLIPLTECLRHAQQRATIDLVVISGDLTEDGDVEDYRYLKEQLHRLLGDVEII
VTLGNHDIKSNFHIGWCGTAASESPYNQVKCYSDMAIVAFDNSRYGASDGVVDEQQFHWL
QQTLAELKNLPIVLVTHHHLLAHQSTTPVWPGTDRLLDLLSSYNIRCILNGHTHHSFTGE
IQGIPYYTVASMSFVGEDEGQGIVRFEERYGYNLYRFESGKLIHQTSENYLPNRLLKVVD
MTQE
>A0A1X6ZFQ0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseovarius halotolerans|TrEMBL
MQKVLVFTDLHILPDGGTIIGLDPAARFELAMDHALAHHPDAARIVIAGDLTHNGAPAEY
ARLRALLSDCPLPVSLMLGNHDRRDAFNAAFPDHPRMAEGFCQQWHDLGDHRLILLDTLD
EHAPDLHSGWLCPARLDWLDAALSGAAGRHVTIFTHHPPIDTGFAAMDDIGLRNRDALLS
RLTRHGTVAQIISGHIHRAISGSAAGLPTAIFKSPCHQMPMQLDSPDCHLSIDEPGAYGL
LLMMKTGVVVHAQDVGLPPAASLRYPD
>A0A087S704|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Marine Group I thaumarchaeote SCGC AAA799-B03|TrEMBL
MIIVQISDLHVGSQFLEEKFNVLVNEVNELNPDVIVITGDLTNEGLMKEYEKCKSLLEKF
NTKKIIAISGNHDYRNTGYLLFKKFFPFQTVNELSDDVVLVTVGTARPDRNEGEVGYRQN
LWLERTMKKFKDKIKIVAMHHHLIAIPDTGSDQLTVVDAGDVLRTVLDSKVDVVLCGHKH
RPWAWNFGTLTVVNAGTATSERVRGLFENTYNILTIENKKVQVDLKIVGGKRVPIDEIVK
NYSQFHDELDNV
>A0A0D6JGW1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Filomicrobium marinum|TrEMBL
MIIAQISDTHIALDIPDADRRATDLALSIADINALDPLPDVIVHTGDIVHNGRQDEYAQA
AAILANARAPVYVLAGNKDNRTALRETFAADGYLAPNLDFIQYAIERYPVRLLALDTSSV
GNKGDFCPERLRHLAGLVAAEATKPIVVFAHHPPFVVSEGPEPVHFESLEVMSELSTLLR
RSGRIVAVCSGHVHRSVSSELEGIPAIVAPSIATALRYGSYPPHMRQKPTYYVHRIDPVR
GFSTETRVAGDA
>A0A7U6Y2W1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodospirillaceae bacterium LM-1|TrEMBL
MILAQLSDFHLSSTNPERTERLARAIGHLMAQDPRPDAVVVTGDVADRGEPAMYAQAAKQ
LSLLSMPIFAVPGNRDWTEPFRESLAPWCGQVENGFLNHVGEMGDLRLIGLDSRRPGSQQ
GQFSPQSKAWLEARLAEQPDRPTVLFLHHPPFRTKLRNGSIGHQIEGVEALEALLRQYPN
VVQILCGHLHRIYAVPVAGIIATSAPSVAYQAIVEHWHEKEDADIRPTATLHYWTDGQLI
SRLSW
>A0A378FXR9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MMATPSTCVQFKPHCANFTLDTVSPGWRWLELHPDGTLTTEVCRLEGAAFHPDIASEGY
>A1K1Q2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Azoarcus sp. (strain BH72)|TrEMBL
MAALLHLSDPHFGTERAPVVEALLHCVARQTIDVAVISGDITQRARRHQFDAARAFVERL
RAGLNGAPVLVLPGNHDIPLYALQRRLLRPFAGFRRVFGPQLEACHEDDSLQLQLVNTVS
RWRHTDGVVRADQVERVARRLEAARPGQLRVIVTHQPAAVVRPQDASDLLRGRERALRRW
AAAGADLLLGGHIHLPYVQPLALPGPDGAPRPLWVVQAGTALSHRIRHEAGNSFNLIRHG
AGASACVVERWDYDEAEHRFACRAQTPLALECGPAEATTRAS
>A0A822TC28|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Shigella sonnei|TrEMBL
MYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL
LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLAT
PSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A090FTI7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mesorhizobium plurifarium|TrEMBL
MKIIQVTDVHLGRRREMRYGANLNERLDRCIDHINQRHGDATLCIFTGDLTDDGEAESYA
DLKAALSRLTVPYRLLPGNHDRRANLIAAFPENGTDSNGFAQSVFDTPEGRLVFLDSLAE
GRVTGELCDSRLGWLDARLGEAAGKAAYIFLHHPPVELGLTLLDPLGLEQPQRLIDVLTR
HGNVRYIFFGHVHRDIAGTVAGIPFSVQRGLHARFMLDLVGDEMVEQAPPAYSIILIDGA
RVVIHSHDFLEQWPLWSPATGQRVR
>A0A3S4BZF2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mycobacterium basiliense|TrEMBL
MHRLRAAEHPRPDYVLLHISDTHLVGGDRPLYGDVDADSTLGELLEQLKHSGVRPDAIVF
TGDLADTGEADAYRKLRGVVEPFAVELGAELIWVMGNHDDRATLRRFLLDEAPSMAPLDR
VRMIDGLRLITLDTSVPGHHYGEIRNSQLGWLAEELATPAPHGTILALHHPPIPSVLDLA
VTVELRDQPALGRVLKGSDVRAILAGHLHYSTNATFVGIPVSVASATCYTQDLTVAAGGT
RGRDGAQGCNLVHVYPDTVVHSVIPLGTGKTVGTFVSPAEAKRQITESGMFIEPSRRDSL
FSHPPMVLTPSGWQSPAD
>A0A449GYJ3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nocardia farcinica|TrEMBL
MPEVTIVQLTDTHIRPPGERLHGVVDTYANLTHVLHQLRASHRAVDAIVLSGDLADNGAP
EAYHRLRAAVEPVAEELGARLIYVMGNHDDRGAFGAELLHSDAALRHPDTTHDQVVQVAG
LRIIALDSTIPQRHDGRLEPAQLAWLADQLREPAPHGTLLVLHHPPIPSPLPATEFLRLR
QPELLAEVLHGSDVRLVICGHNHLTATAALAGIPVWIGPALAYRLDPLAPVGRQRGLTGF
GYSRIDVLGTSMVATAIEATPAGIVYDRAEQDVLDQLAALAAEAR
>A0A1A9GHR5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nocardioides dokdonensis FR1436|TrEMBL
MTSPVPLGQHPPATHVLAHLSDPHLLAGGALQYGVVDPEAGLLLALERLRRMHPAPRALV
FTGDLADRAEPAAYRRLRELVEPAAAEMGAEVVWVMGNHDERAAYALGLFGEDADPDAPQ
DRVHDVDGLRVIALDTSVPGYHHGEITPAQLVWLAEELAVPAPHGTVLAMHHPPIPLPML
RAAETIELADQHLLADVLAGSDVRAVLGGHYHYSSHSTVAGIPVSVASATCYTTDPAPLA
RFVSGVDGHQGLNAVHVYADRVVHTVVPLSAAPEVSGFPADVTAQVEALTPEERRELISR
KDSPFNAGTLPLH
>A0A1W6LNV9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sedimentisphaera salicampi|TrEMBL
MSGKEINRRSFLGGAGALAAGIMVNSGAAAKAAQNSSEASKQTFRICHLTDIHITPHRDA
PETFEKAIKRINSLTPKPSLIVTGGDNIMDSFATPEKQVKRQYKVLDSLMAKTDIPVKYC
LGNHDLWGWNKSKSKTTGEEAKWGAKWAIEHYGLPGEYYSFNHSGWKFIMLNTVKPDPND
KNGYIGGIGEKQFAWLENVLAGMPSDMPAAIISHIPLLTVTNFELLDSGANLPRINPGWI
CYDGPKAAKLFKRHKNVKLCLSGHMHRRDRIDYMGVSYICDGAVSGGWWRGPHRGCEAGF
GLLDLNSEGSFNHEYIEYL
>A0A086LF17|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii FOU|TrEMBL
FICRPLFGSLAQMFPAQLGDRAAELRKNRNKWKSIIDGHERR
>A0A4W6DPW2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lates calcarifer|TrEMBL
MLWLCGVNRTAAVWVQSMKSQMDRGVVDLQELRRNLELAAAMLDAVYTDETRRLLDTEDE
LSDLQAESVPSEVRDWLACTFSRKMGVAKRRPEEKPRFRSIVHAVQAGIFVERMYRRTSN
MAGLTYPPTALTALKEVDQWSFDVFSFHEATGDHALKFLVYDLLTRYDLINRFRIPVQAL
VQFVEALENGYSKHRNPYHNLIHAADVTQTAHFLMLHTGLMHWLSELEILAMVFAAAIHD
FEHTGTTNNFHIHTRSEVAILYNDRSVLENHHVSAAYRLMAEEDMNILVNLNKDDWRELR
SLVIEMVMSTDMSCHFQQIKTMRNALTQTHGIDKVKVLSLMLHAADISHPAKAWPLHYRW
THSLMEEFFRQVLCCSGIHEAVFRADKITLHTATQGLCCFLMSMS
>A0A1Y3F3F3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Trichinella nativa|TrEMBL
MLCLLFKRLQEANRRTHVASELMMYHTQKACLAMFYDLGYAHKFRIKRRKLSRFLLLVEK
GYRDVPYHNWYHAFTVTHFCYLMLKTIPELRQHLSDVRCMCLLVACLCHDIDHRGTTNSF
QVQSKTALAQLYSSEGSVLECHHFAQTMCILNIEECNIFAELPASLYQTILDNIRDIILA
TDLAQHLRIRPEFIEMVESGLQRGNPRHVYILLSVLMTACDLSDQMKPWKTSKNVAAKVY
KEFFSQGDLEKAMGNRPVEMMDRDRADVLKLQIDFLDGIALPLYKYVHFN
>A0A1V5V9Y6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|bacterium ADurb.Bin236|TrEMBL
MRKMCLAAAALALSLTCNSLVLRAQEQTAAGEAVFSEAVFEAEAGGVVAYDVADWKLMRM
DTLSGGAAVATEKRGAAMEFDFTGEAVAGDFVIGKTGGRALASVDGRPAATIDLYKNIMT
PSPERIVLVNGLKPGAHKLRLEILNESNPGSKGALVAVDALRAAAASYGAVSGTLECVHN
EGLPVTRAKISATGDSVELRAITGVSGEFVFNALPPGEYVLRFEKPGFEPLEKTALKIES
REEISLGRVMFEERTGARPLKDIRMPNRARPALARPGDEFVIEVIAPAEAGEWSAALENE
FANYPLEIAEASFNPDNGRWTLKAIVPGGASSLLYGLRVKFSGGEDFQPRSVMVSPEFKN
SIRVVHLTDVHVYKSESLFDVYKKLAEEINLVNPDLVVITGDLTDTTGYTSERWPESDQY
PAMLDLWNSYNAPVFIVPGNHDLSPYKKEEDYLVWNRYFDTTDFSFDYGAYHFTAFDNSF
VYRSGGSDEPHAEDLSPEQLEWLDADLAAASGALMRIIMFHVPLHNTDSKVKEIAAQRDV
RLALYGHLHMDVVDKLPPVAYVQTGAAFEGSYRVLDLADGRVVEMNAKKDGFTAFKTGMV
ISATKRAEDGRAVAIKAKNSGTMALPNAAARVEMPTAKGYSCDGCSVVSSFDKDGKTLVT
INFDIPAKGTASAVLTAE
>A0A483ABJ7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured SUP05 cluster bacterium|TrEMBL
MKHFIQISDCHIDDTAQSLGVDSQKNLATVVNKITTLPSDALLISGDLTHNGTLQSYKIL
KKILSPIQTDIFVIEGNHDNFEHLNAEFSSCLFTQFTLGLWDIISINSVQIGKTSGFVSQ
HALAKLDQQLSHSSAKYSLVVLHHPIVSMNSTWDDTLSLENPDDLFALLKRHPKIQAALF
GHAHESAEFNKNGIKIIACPSTAVQFNHESRIGFNHYTLLDDGQLHYTTQWI
>A0A0F0LCJ3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium azadirachtae|TrEMBL
MTAQFGRYAPPTHTLVHVSDPHLLAGGAALGGHFDVDSTLARTLAAIESATDRPDAIVVT
GDLADLGEPDAYRRLRSMVEPVSERLGAPVIWVAGNHDERPAMREHLLDVPPAEDPITGV
WDLSGLRVIALDSTVPGWHHGDIDAEQRAWLADQLRTPAPHGTLLAMHHPPVPSHIPFFD
ILELRHQDEFAEVLRGSDVRGILAGHLHYSLHATFAGVPVSVASATCYTMDVASPADRVN
GMDAAQSFQLVHVHPETITHTVVPVVEATPVDTFSPEWVERMARLTPEQRLEAFSRKPGR
>A0A1E7WRJ5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Duganella phyllosphaerae|TrEMBL
MPNQVNHEPSNEPSNEPQTSRRTLLKMGLASASTLSVGGLLAGCGGGSDAVSATPAPAPT
PTPAAKISSFALAVLPDTQFYARYATSGESNQYQRHYGNEPFAAQTNWVARNAQALNIPF
LIHLGDVVDQVGKPEQWKVADSAMQVLEVAKLPYSILAGNHDVLNDLDYNGDQSRGTDAQ
RVLANEPYLQWFGARRAQRQATFGARDPSGFHEYHIFTAQDQRFLVLSLSWRISDAGIAW
ARKVITDNPTLPVILVNHQLMNIAPDAVTPLETDYGKMLWEKLIRDNDQIFMTLNGHHHG
AARLTKTNNFGNPVEEMVVDYQMAYQGGNGLMRLYEFDLTNKQIKVLSFSPWVPMKPADT
LNAFDRAVLTEANQAFTIDIDFAKRFARFNPTFGVGQVTVASSLVEQARAMVLKGYTEPA
VVEPVVPKDADDYPKVASTVAHWRFFGGADGAAVAPGTRIADVTGANPLVRDALNVNGVK
NAEAGDIVWSTDRHRLSSAPGSVSFINTDKNVPRLSYFVTDAAAAINAQTFATTGYTIEA
FIKINPAWVNSKHAWMNIMTRDGKRGDLAGFNGGDAESPPLLFAISSLREVQWEVVPDVS
GARGGLASWSGEIIAGTWVHVAIVNDPVTHDTVMYVEGAPVLRNSSNVVGLATLSARSPW
VVGGGSWDGERADGFFGNIGEIRVASGALKPAQWLTARRS
>D1ALZ7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sebaldella termitidis (strain ATCC 33386 / NCTC 11300)|TrEMBL
MKRTFFTVLFGIIISVSAFAKTSFEIVALGVNGGVIDGNITSYLIRSTDENSYLALDAGT
LLPGIEKAAAKGAFKNIAVPADSPLTLEGYVFKNAVKGYFISHGHLDHVSGLVISSTDDS
KKNIYALQSVVDVLTNNYFNWKTWPNFSTSGEGFKLGQYTYKVLDPGKETAIEGTSLFGA
ALPLSHSNYESSMILVRKNKDYFAFFGDTGPDTVEKSTHLDTVWKTLGPKVKSKNLKGII
IEVSYQNGIADKDLFGHLTPEWLLKELQNLEKYSGGKGSLKGLNVIISHVKPTLNKNTDI
RSSILGQLKNGNTLGVNFIMLDQGDSMEF
>L1LE45|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Theileria equi strain WA|TrEMBL
MSNIFMNRDLVRSAVLDVENFLQSNSADDDTMNSLKLIKHAIVALDNLKVNYDIRSTSTL
VPSAQDKHSQIQSDISSGTIPNADLKNNWSFTLKDFADSLLHSPLFSQCCARESVHPFDT
ERTESVHVNDTNLPSDEKTAESNRSGVYNRHFIGKSKRNVTLKDECVEEYMRQLGNNWHL
DILALANLPSVLSEGPIISIGRHLLKPIGDTIDPNFNELVLPVLRDIQDVYIPNPYHNAL
HGAMVGHLSQVLFKAIRSERAFTPYEELGYVLAALGHDAGHPGKTNTFLSLTSNPLALIY
NDNSILENYHSSLVFHIIRYHSKFFNLIPSKEWEKIRKRMIQLILSTDMTTHFTHINNVK
ARRESGSFDIKNDDDFWLLMVLCIKVADIGHNFLPWVDHISWTSLLFEEFYLQGDEERFL
SMPLLLFFDRTKAADIPDSQLGFFQGFTKPLLDELTIFENESKFISRVLLGNAEKNLKYW
KDSSLKNIEDILRDLDSSGEELAVEDQYVD
>A0A8D0KKQ4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salvator merianae|TrEMBL
MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD
LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDSVPSEVRDWLASTFTRQMGMMLKR
TEEKPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIGVLKNVDKWSFDVFALNDAS
GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV
HYLLFKTGVAWLLHLDWDRNTNKICVKDFYHLRRNQRMFILLFCRSDTAILYNDRSVLEN
HHLSAAFRLLQDDEEMNILSNFSKDDWREFRTLVVEMVLATDMSCHFQQIKAMKNALQQP
EGIDKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDKEAELGLPFSPLCDRK
STMVPQSQIGFIDFIVEPTFTVLTDMTEKIVTPLIEEASRSGMTGFRRSSLNSISPSEVK
RSSVKSTGSEGSASLNCSLLTVDFKCFKATWTEVVQQNREKWKAQATKEEKAKKEAEDNL
QQGTDEKKTDDNEGKKLTDEPTGVKSDGSKEGHSGACKSTEASKSNVNGTRQTGGSRHDA
SQGKNVTQAEKASEPNSTAGEQKRHVQNGKPVDRFMQWGSYSIRPPIRSSKKPNFASTST
SFPPFQKKSEDYLVRYKLLDQRGRMKKIQHISQHWNRK
>A0A447Q5U5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serratia plymuthica|TrEMBL
MTHTFLVAQISDLHIKAQGRLSYKKVDTLGALHAGISKLNRLEPRPDVVVITGDLVDFGR
DDEYHTLRQALAALTIPYFVVPGNHDDRQSLRLAWSESPYLAVQDEFVQWVCDDYPVRLI
GLDSTVPGQSGGLLCERRLEWLEAQLVKAPNQPTLVMLHHPPFVCGIDHMDQQRLANPSA
LAAVIRRHPQVERILCGHVHRSIQTLFAGTLACSAPGLSHQVALNLHAGAPANFVLEPTA
FLLHRWTAEQGMVTHNCLVNDYEGPYPFYDDQGLID
>K0NSU0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactobacillus equicursoris 66c|TrEMBL
MKVITDKANPEFWLLSDPHLIADSLHDFGPRFEQMQATSAGKDITYQETALRAFVKKVVE
EKPDAVVITGDLTFNGAKASAKKFAELFAPLKKAGVALIAIPGNHDIFDGWARRFEADQE
YRVDQLSPRDWREIFSATYDLAESLDPNSLSFAVNLNPYWRLICLDSNIYGHQESYGHPI
TSGNLTDSERAWLTQELETGQKADQEMLFFMHHNLYDHNSVVHDGFKLNNAAELLALLKK
YPVRCAFSGHIHAQHIMAKNVAIPEIVSSCFAETDQGYGVVKLGNDQLDYLRQTFDIDRY
LTEQEKKAYPFNDFHSYLVKVFDGANDQLMEHFLTFDGTAEGQEAISLLKKLHWNFFTGQ
GNLTPAELDTLKKSATYQKLLQMGPNLRWYLNSLTESQESSQELTLTW
>A0A447I7B9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Devosia equisanguinis|TrEMBL
MSAPTTFVHLTDLHVGNPAVQDDHLHSDTTATLRAILADVKKLSPQPDFIVASGDLTNRG
DAGSYEHLKDLIAEAGLDMPILFALGNHDRRDGFYPAMLGRTSELDQPYDHSAVIGGLHV
IVLDTSVPNKIGGAFEPGQLDWLLSELGSHADLPKLLVMHHAPALDTHDPSMEWESLSYA
DTEALRQAVTGKSVIGILSGHIHYDRVANWYGIPTVVGIGQHAATDVLWLHEGLRMLEGA
AFAIGKVRPSGLSITFAPQPATRREIGGFRFADMAEILKKYEADTTVAAAE
>A0A086JNU3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii GAB2-2007-GAL-DOM2|TrEMBL
MHISCVKGRIVARQIDNVFTVIFAIEVLGKFVSYGLEYLQDPIESFDTIVVLTSFTLLVL
GFYVSGIGLLRILRLLSALALLHKYPDSKEKRPELSAGNSSKLEKASSIVEGLLTNVHIP
KYFKTELEWVWDSILANKVYDSHVVENEEEEEDQATETIIAGSDASRKTQAAVRASRAQS
RASKLPHGSSSMVVGTTNGRISGQILETLREPDPRMMDAALYKSETRNLDPLTATVGGMK
NSPSMFAKGSKSSNMMGSSASKSFRTERNKKAIDIISVLYQASQITGAEQEQVNEAMRPF
DEWQWDALHAGDVCDMNLLPVVFVRAIATFPTIMTKFNFDLDRLFDFLKVVQTSFQKNVK
FHCAAHTADMIQAMHYFLTIGKLGALLSEYDVFLCHFCALVCHFGHPGVTNTFLVKSRHP
RAIRYDDESVNENYVASAISCLVAREEYNFFGDKLPLWQVFRLHMIDILLNFDISKSAHQ
VAMFRTKVSIKFTASTPADKQLLLTILLRAADYSFTCRQLALYSKWKDRMIDEFFAMGDT
EKQLALTVSPFCDRELTNVDKCHVAFAEVAVKPLMTVLVLGLAPHLQKDVLDTLEANQKN
LMQKLDKSD
>A0A1I8BAF9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Meloidogyne hapla|TrEMBL
MHELSKQHSLTSVTYTLLRERKMLFKFEIPASTLVNYLLHLEHHYRSNPYHNQIHGADVA
QSISVLISSPALEGVFSDLEVLAAIFASAIHDVDHPGFTNQYLINTQSELAIMYNDESVL
EQHHLAVAFKLLQDRDCDFLQGLTRKQRQSFRKMVIEMVLATDMSKHMSLLADLKTMVEA
KKVSGTDTLLDKYQDRIQVLRSAIHLADLSNPAKPIDIYRQWNERILEEYWRQGDREKQL
GLEVSPMCDRGNVTVEKSQVGFIDYIVHPLFETWAELVHPDANSILDQLEENRQWYLAKM
EEEEENEEEQKQIIKERPPLPQPFCSKERAAMRQTQPPESCFNISRSSSKTLNHPRPRAA
TTTAVILPESDINEQRH
>A0A2K8W2B4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Dickeya solani RNS 08.23.3.1.A|TrEMBL
MLLAQISDTHFRSPGQKLYDFIDINAGNADVVSQLNALTERPDAVVISGDIVNCGRPAEY
QVARQILGNLAYPLYIIPGNHDDKTHFLEYLQPLCPQLGNDPQNMRYAIDDFATRLLFID
SSRAGTSKGWLTEETLAWLEAQLMRDDKPTAVFMHHPPLALGSAQMDRIACENGHRLLEL
VERFPSLVRIFCGHNHCLIMTQYRQAVIATVPGTVHQVPYYHEDTRPYYDMSPPACLMHR
LVDQQWVSYLHPLSHYAGPWLYNENISCPVDER
>A0A150HGD2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium laevaniformans|TrEMBL
MAPASLSFGIHPPAQRVIVHLSDTHLLAGNRPLGGRYDTAANLTATLAALERTGVRPDAI
VFTGDLTDLGEPEAYAALRAQVEPVAARLGAPIVWVAGNHDERPALREGLLDEPPSLEPV
TGVWDLGGLRLIALDSSVPGWHHGDLDAAQLDWLRGILAEPAPRGTVLALHHPPLPSHIP
FFDILELRHQSEFAQALAGSDVRAILAGHLHYATAGTFAGIPVSVASATCYTMNLQRPPQ
EVNGMDGGQSFHLVHVYDDTITHSVVPVGEAETADVFSEEWTRAMAALSAEERLEAFSRK
R
>A0A163PTF3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oerskovia enterophila|TrEMBL
MTGALVTSPPVVMAPRSDGFEVVWGVSRLCRGWVEWESDDGSRGTASGDAFGMVPQGARV
LRVRVEGLPHGSTLRVRTVTEAVDASSPRHESAWKSVRTLDGSSEDARFAVWNDTHQRDD
TLRALHEATPEVDVLVWNGDLCNDWTDPAEFTTTVLNPAGLDVSDGRPLAVVVGNHDVRG
TWAYQLEDFVATPEGRPFTAFRIGPVACVVLHTGEDKPDAHPTFEGRVAFEPLRAEQARW
LREVTARPEIADAPYRVVFCHIPLRWIDETVVDYDADGYDWFSRMSRDAWHDALVGWGAQ
IVVSGHTHYQTWLPATEEFPYAQLISGGPDADTASDEAAAWIDGEASADELVLTMRDLAG
EVLHEVRLPPLA
>A0A819WRV1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rotaria sp. Silwood2|TrEMBL
MLLSENLSPIFSSKSKSTDSIDNGGISAGRISHETIEHDVTNLSNMNNLPTTNAFEALQV
SSDRLRTIIAALHCNILIRKADLVRNLDYVANVLDATHQDETRRLMEEDDGALSEIEPDT
VPNEVRDWLTMTFTRSMSTLKRRPSDKPRFKSVAQAIRAGIMTINEWTFDVFSVNEFTNG
QCLRYVGFELMQRYNLPNKLHISITALQNFLEQMESGYSKYRNPYHNLIHAADVLQTTYQ
IIYSSGLMNWLSDHELFAMFVAAIVHDFEHTGTSNNFHIQSRSDVALIYNDRAVLENHHV
SAAFRLMRQDEYNIISEFTSEEYKNFRHLVIEMVLATDMSCHFAQLKTMRSLLSMPE
>A0A1S8LH23|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium felsineum DSM 794|TrEMBL
MLIVVIIILIILSSRVFIDNNVIQICKYKIFSKRLPKEFNGFTIVQLADLHSKRYGDDNA
KLINKINKINPNVIMVTGDMINDDGNYSVCIKLLENLSSKYKVYFIVGNHEQNLRILNPH
KYNNMMAELMKIKVDVLLNEKREILLNGKIINLYGAFMESRYYRNMLDKKSKSIEFTLED
LEENIGQANSELYNILMIHNPIFFETYSDWGADLVLCGHMHGGMVRFPLIGGVFSPENNL
FPKFCSGIFQQNNASMIVSRGIGIGSFGFRFFNRPELTVITLKNK
>A0A1N7S6A5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Paraburkholderia piptadeniae|TrEMBL
MLLAQISDLHIKRPGALAYRRVDTAAYLARCIERLNALDPRPDAVVMTGDLVDQGEPEQY
AHLKSLLATLEIPYYLLVGNHDDREALRDAFSEREELRTGGEFVQYAVDIGPKRGPLRLI
ALDSMVPGESAGLLCDVRLAWLEEQLDAARGKPVIVALHHPPFVTGIGHMDALRLEPTSA
DKFAALVARHPNVERVICGHVHRPMFVRFGGTIASAVPAPAHQVALDLRDDAPSAFMMEP
PAFALHRYDSVNGLITHHAYVDAADGPYPFYEPEGTLID
>A0A0F0C9T8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium sp. FS41|TrEMBL
MKRKTWMISALMYAMVFMACFGVLHFMKKVMEPPGPVQVAGTEPIEEPSDSPRGTREDTG
EPVPAATDSEAEKEETVEREGGYTGWKKEFPSVWTPPQETEVPYVPPDVILATDLHYQSA
LTDDGGEAFQLFVERSDGKVIRYLPQLLEAFLDEVIEEKPAALVLSGDITMNGEKVNHQE
LADRLKRVQDAGVQVLVIPGNHDINNGNAAVYYGAEKAAAPSIDGPEFYDIYHEYGYDQA
LSRDSDSLSYVYALDERNWLLMLDSCQYEPDNKVEGRIKDTTMAWMDEQLAKAGEEGIFV
VPIAHHNLLAQSRMYTTQCAMDNNQDVIQLLQKYRLPLFFSGHLHVQRVRKYKAEPGVPE
AAYGIQEIITDALSIPPCQYGHIIWEEDGSISYETRSVDVSAWARRTGIDNPDLLDFEDW
SFRYIQKLISDQIRGVVKNLGNDVERSMAATYAGVYIDYYAGRKIDAKGIKGTRGYRWWE
RNMPDSYLLRELNAMIADSDRDNNYFLLPEEQGWFLD
>A0A1S8LAR4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium felsineum DSM 794|TrEMBL
MKTIFISDTHIGQNTPENWYQKSVHEKYLKAILQYVQSNAEDIQDVVILGDWFDLWMYTP
QPQISATLNNIINNNLNVFTKQSDGDFITCMDSIQGNLYYVHGNHDMNIDFNQVNKYFAP
LSSKNKQVICTDRIYGKNGIYAEHGHYYDTLCKPYSGKTDKYKPLPIGYFISRIAAWWCE
KQLKKAGKSNSSELQNQGNPSANDFWTIIFDNDFYKIVFTMPDGTSIKRSDVLNLYPDLV
TSWEDVTKLLTVDLNNCLDNYGANLCNDSYNGVKNKVVVMGHTHVPTMQQHLNSVYVNSG
FMCPAVPDVSDGNMMMTFVEVDQNSSSYTVTIKKVNYPDTSIINYNQCIV
>A0A1R4JJQ2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium esteraromaticum|TrEMBL
MSARYAFGRHEPASHVIVHVSDPHLLADGAALGGRYDVETNLARTLQAIRSVNVQPAAIV
VTGDLADLGEPEAYQRLRRAVEPAADELGCPLIWVAGNHDERPALRENLLDLPPTEEPVT
GVWDLSGLRLIALDTSVPGWHHGDLDVDQLEWLRDLLREPAPHGTLLAMHHPPLPSHVPL
FDILELQHQEELADIIRGTDVRGILAGHLHYSSHGTFAGIPVSVASATCYTMNVALPAAE
VNGMDAAQSFQLVHVHPGTITHTVVPVTDARTGDYFSPEWAERMAQLSPEERREAFSRKP
PR
>A0A3S4F1F0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salmonella enterica I|TrEMBL
MATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIG
EQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHS
LRNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTI
APGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A447P7I8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salmonella enterica I|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRGATV
>G8TNE1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Niastella koreensis (strain DSM 17620 / KACC 11465 / NBRC 106392 / GR20-10)|TrEMBL
MKPVFVTLAFACLLFCNHSFSQSSFKIIPLGVKGGIDESNLSAYMIAPTGSDAWVCLDAG
TIHYGIEKAIQAKLLKGTSAEVLKKDIKGYLISHAHLDHLAGLIINSPDDSTKAIYGLDY
CLEVLKDKYFSWKSWANFANEGEKPALGKYHYTTLTPGSETPLQNTEMQVTAFSLSHSAP
YQSTAFLVRHNESYILYLGDTGADSVEHSDKMHQLWQQVAPLLKAKKLKALFIEVSFANE
QSDKQLFGHLTPHWLMSELQDLAALSGADALNNFPVVITHIKPGGNREQMIHVQLKANNP
LHVKLVFPEQGKLLSF
>A0A1R3TUQ7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Agrobacterium sp. DSM 25558|TrEMBL
MKLIHLTDLHLVPPGAMLFGFDPADRLRETINRINRDHADAELCVVTGDLTDEGDAAAYD
LLRDVLQELRVPTRLLLGNHDHRGHFIKAFPDEPCDENGFVQSVHESSAGRLIFLDTLVE
GFGHGSLTDGRLEWLLARLDEVQDSPVYLFAHHQLQPIGLPHFEPWNTENWHQIMQAIVA
VGNVRHIFHGHVHVDVGGSWRGIPFSASRGVAHQIIPHFTRRDADFVEDAPAFDVALIDD
DGVLVHRFEVSDRNVVAVSEAGPLLGGTQ
>U4T7P4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Psychrobacter aquaticus CMS 56|TrEMBL
MLSYPVNKISTPDQQLIILQITDLHLSTAPAYTTNDNSNETLCQQCFETALQQALQTDTR
CDLIIVTGDLVSKVQPAIYDYIFEVLQATNIPFVCIAGNHDVTDEMDSHLPFFQRELIAQ
PADARLLSRHVIETDNWQLLLLDSSITGKVAGEITLTDIDWLREKLSTCDKPALIALHHH
VIPVDSEWIDNHMAENAETFWEQMAAFAHLKVIISGHTHQEQVRHRQGVTVYSTPSTCYQ
FKPYEDNFSYDKNARPGYRWLQLANNGTVASWVERLDT
>A0A6S6TML3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Thiotrichaceae bacterium|TrEMBL
MTLQLVQITDTHISLDAPQRMKDLENCIKAINELPVQPDLVIHTGDIAHTGQAEEYHIAK
QLLDQLNTPYFVIPGNRDRRAGILSEFIDERYQLPPQGWIQYSIEQYPVRLLMVDTLDEQ
NNKGHLCAERLEHLETMLLADTTKPTALFLHHPPYEATGIPDPFQYKDWNDVGKLHSLLS
RFDNICGMYCGHVHRFIDGTIAGVQASAISCMAGDLRKGEVSDADRKLPVFKTLTLPG
>A0A2P4UJY2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Actinomadura rubteroloni|TrEMBL
MAIIAQLSDIHLAAGRDGTVDDGSGPVRALRAAVSSLLSLPARPDAVVLTGDLADAGLPA
EYARLHALLSPLPMPVYPLAGNHDVVDALRAAFDERPAVVASGSRPGAPLQYTADVAGVR
LVCCDTSVQGGASGCMDDERLEWLDAVLAEAPEKPTVVATHHPPYPIGIRFIDAMRFENH
DVFAKIVSGHPQVVRVMSGNVHRGSAGSFGGVVCTTCPSTYRQLFLDLTQPGHAAVTGEP
AGFAVHLVTTDPPGTATTHFVPTGSYRPLMDVE
>A0A378LS85|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Legionella wadsworthii|TrEMBL
MSSREKKLKIIQLTDLHLFQDDSRLFEIYPDQTFQTVIKNAQEDLADADAVFLTGDLSQD
ETMKSYEIIANSLKDFNHKIFWIPGNHDSIANMKSVFHQKNHFVSEKLFLTEIWDFVFLN
TKKEGVEFGLLEEKEFEFLACELKKKRTKPIAIVMHHHPIEVSTPLIDKYILQNKEEFFS
IIKWSRVHLIICGHVHNDYSLHYHNIHIETSPATSIQFKKGAIKLELEKQIGYKIYYFSQ
NDYMCQTKIWHLE
>A0A139XXJ3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii ARI|TrEMBL
MHRLLDWDFHVLALPPASAVLVTRDLLTQFALKANMDIPGEILMAFSVAIYKNYRPNPYH
NFYHALNVTQVLCLLLALPDVAAQFSPIDYLVLSVAALGHDLGHPGANNLFMTRFDCWPS
RIYQNVSVLENYHAASLFQILRHPAFNVFCSVSPTNFAPIRKRIISAILWTDMAKHFDVV
AKLQAKIQGEMVLAEGIIVTLTKPYLEGLLLHAADISNPMMDFELCRDWAFRACDEFYQQ
NKMEEMGGFPPSMPSFEHFDEYNVAKCQVGFIDAICKPLFNSLALMFPAQLGDRATQLQK
NRCVPLIIFPT
>A0A2H6GXF9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|archaeon BMS3Abin16|TrEMBL
MRLVHISDLHFGSRFNETAFESAVEEINSLEPDALVVSGDLSDDGLTHEFERARDMLKGF
KCKNLIVCPGNHDYRNTGYLILKDYFSLKQVYETEVAKIIVLKTARPDKNEGEVGYRQQL
WLEKQFRDTGKTRIVVMHHHLIPVPDTGVERDTVIDAGDVLAALKRSKIDLVLCGHKHRP
WKWDFEGLKIMHAGSLSDIRLRGFFHNSYNIIDVDEKGIHGTVKVIGGDELSFDVLEKER
MN
>A0A673ZEA1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salmo trutta|TrEMBL
QGLIRSLSPLRQGLDFRSIVHAVQAGIFVERMFRRAYTAAMPDQPAAVVNCLRDIDRWNF
DVFALNTACHDHVLQTLFLELVTRYELNSRFKIPISILMSFLEKLEKGYSKHNNPYHSSV
HAADVTQTLHCLLLRTGLVHWLTELEVLASLFAAAIHDYEHTGTTNNFHIHTKSDFAMIY
NDRSVQESHHISAAFRLLQDDQSNIFMNLSREEWMELRALVIEMVLATDMSSHLVQVKAI
KGCLQQHEGIDKPKALSLLLHTADISHPSKPWGLHSRWTKALMDEFFRQGDREAELGLPF
SPLCDRNSTLVAESQIGFIDFIVDPTFSLLTDMAEKIVIPLVEDNPGPPDPCNRHR
>A0A653W688|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Halomonas titanicae|TrEMBL
MKETNSDPRLAGLNVYRVGGAVRDELLGWPVYDNDWVVVGTTPDAMRKRGFKPVGRDFPV
FLHPETAEEYALARTERKSGHGYGGFEVHASPDVSLEEDLLRRDLTINAIAQSTEGELTD
PFNGQGDIERRVLRHISAAFSEDPLRVLRTARFLARYASLGFTIAPETQALMRKVSHSGE
LEHLAAERVWVETEKALGEPSPEVYFTTLERCDALNVWWPELAGEALVKGLAAMAEVPDS
DMFPLAHWRHAQLVSPLSAEQRDALSERLKLPNAVAQLARHTALTYSLINHSLKNHALPS
DALEGPSVLRWLERLDGWRKPEQVEGQLALVKVLAPEQVGPLENAWQAAREVSPQALIAE
GYQGAALGEALRARRGQAVEAALTK
>A0A0J6CB52|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bordetella pseudohinzii|TrEMBL
MLIAQITDLHIRMPGQKAYRVVETDRYLPPAIKALNALAPAPDVVIISGDLTDFGRPAEY
HYLRDMLAALRMPYYLMPGNHDAREQLRESFPEHGYLRQGGAFTQYTVEHLPLRLIMLDT
VVPMQSHGMLCDERLAWLEARLLEAPDRPTVIAMHHPPFKTGIAHMDRIGLLQGADALET
LVRRHANIERIICGHLHRSIFQRFGATLASTCPSPAHQVVLDLRPEGPAAFNLEPPAYHL
HHWRDGRLLTHHAYIGEYPGPYPFHENGELIDD
>A0A447V2G8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cedecea lapagei|TrEMBL
MLLAHISDTHFRSQNQKLYGFIDINAGNADVVSQLNALRERPDATIVSGDIVNCGRPEEY
QVARQVLGTLKSPLFLIPGNHDDKAHFLEYLSPLCPLLGHDPENIRYAVDDFATRLLFID
SSLAGHSKGWLTDNTVAWLEAQLTASGDRPTAVFMHHPPLPLGNAQMDKIACENGHLLLD
LVARFPSLVRIFCGHNHCLTMTQYRQATIATIPGTVHQVPYHFEDSRPYYDLSPPSCLMH
RQVGEQWVSYQHSLAHYAGPWLYDAAISCPIDER
>A0A0F8CQP6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ceratocystis fimbriata f. sp. platani|TrEMBL
MLAPNEAPALQVIVLGSGGGPLESNTTAFLVRSVASGWSKGSIVAVDAEKGPFAGLELQN
KSALANGARITHDLIDTYLITHPHLDHISGFVVNTAALSGTRPKKLAGLPTTISAFKKHI
FNNVIWPNLSDENNGVGLVTYMRLVEGGNPALGEGDGKGYVEVNDGLAVKMWSVSHGHCM
ERHSHRGSTSSQGGFGSGGSVDAGRGSLLHSTTVNGTSHIKNSISNGSGHTNHHNGLVRP
SGLINQATALAAQSCECRERICVYDSSAYFIRDVATAREILIFGDVEPDSLSLSPRNHQV
WLEAGPKIAQGHLAAIFIECSYDNSQADERLFGHLKPVYIMEELQALAEQVRAARLDTSV
LRESRKRKREHNSMLTTVKQRKPPPPSLEDQDPVSPKSMRPVSHVAIATPEGSRTSHISS
PVSELSLLDDVEALPGSLSPLPPAIQNHDTQTHIDIKSDFPLRGVKVVIIHMKEKFTDED
DVGVTIKKELDELEAAFKLGCEFIISYSGQSLYL
>A0A222TQR0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gordonia rubripertincta|TrEMBL
MFVVAHISDLHFNGTRFNRSRIQSTLSYINARAAGIDVLLVTGDLADEGVPSEYREAYGV
LDSPLPMLITAGNHDVREPFSATLLGAETSAPINHARRVGEVLFLMCDSSVPGRNDGYID
DQTIAWMSAQLEVEDPQTPVFVAFHHPPVELHMPFMDSIRQTGEERLVPLVERHPNIVAF
LCGHAHTSAVTRFADRPLCVAPGVASTLNLPFEGTDIVNRGQPPGIAFHIYDKGRLVTHY
RSVMF
>A0A5P9GZD0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseovarius sp. THAF27|TrEMBL
MQKIIVFTDIHFVPEGETIIGLDPAARFAQGLAHAQKHHPDAARIVITGDLTHHGTDPEY
RRLQAALADVQIPVSLMLGNHDRRAPFRSVFTDAPQTPEGFVQDAIDLDDTRLVLLDTLN
EDADDTHSGLLCDDRLDWMEAAIAGAQGRRVILFLHHPPILTGFGGMDWIGLKSRRQLAA
RLEGHDSVHQIVAGHIHRTIQGGFATGAGNHIPTAIFKSPCHQMPMALGFQDPSLSVDEP
GAYGLLLLGPDGIVVHTEDFTLPPADRVCYDTQRG
>A0A259UA71|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sporomusa acidovorans DSM 3132|TrEMBL
MKIFAIADTHLSGQPPTKPMSVFGKHWEGHWEKIKTSWQEQVTAEDVVLIAGDISWAMKL
ADALVDLNAIADLPGRKIMIRGNHDYWWQTVSKMKKATEDKFEFLNNNFSTAGQWAICGS
RGWICPEDPLFKTPDQAIFKRELLRVEASLSAARDAGFTRIILMLHFPPLYNQQIGTGFS
DLINKYEVAICIYGHLHSESSIKAAATGMINGTFYELVSCDALGFTVKQII
>A0A099YUI4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Tinamus guttatus|TrEMBL
LRYMVKQLETGEVNIEELKRNLEYTASLLEAVYIDETRDAVPSEVRDCLAATFTQQARAK
GRRAEEKPKFRSIVHAVQAGIFVERMFRRTYTAVGPSYSASVLSCLKSLDLWCFDVFALN
RVTEDHALKTIVFELFTRHNPNSAFRGNVHAADVTQTVHCFLLRTGMLHYLTEIEVLAIV
FAAAIHDYEHTGTTNSFHIQTNVPLSPRSDCAILYNDRSVLENHHISAVFRMMQDDEMNI
FVNLTKDEFAELRALGIEMGLGADMACARRAGECAWCCGRSPVAPWCPHAAPARAMGTVL
PRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKMVLPLVEDGA
KAKGNPAGGQPAR
>A0A178WVZ0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Amycolatopsis sp. M39|TrEMBL
MRVFAHLSDIHLDGSERADARAAAVTRYLRNLENPVDAVFATGDIADHGLPEEYRRAAEL
LDLPMPVVVCPGNHDVRARFREAMLGQPASDAPVNSATKVADLLLVSCDSTIPGKGAGYL
ADETLAWLDDTLASHDGPSFVAFHHPPLDVGVPLVDAIRQTGEDRLAAVLKRHPGITALL
CGHVHTGAATEFAGVPVRIAPGVVSGSLLPVEPGAERGWDEGGPLDFDSPPSLLLHVLYD
DGRLTTHQRAVTE
>U6L6W6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Eimeria tenella|TrEMBL
MVTMWGVWNSVASYRLEENREEGDFLSTEENTALEACTALSYLFGFLPVVILDVVLPSRT
KYSWVTHLSFLGTSAATIIVRGVLNPRFIAPSFVTRGGGWTGWSRT
>A0A368G9B9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ancylostoma caninum|TrEMBL
MAAELLVQGSQLLISEEDVRKLTNETIKDWRYWSPNFARFSFSPRSIGDGDAYMSASMTM
FNDLGFTARYSMNKKKLASFLLRVARGYREVPYHNWSHAFSVAHFCWISLRTPAVLHGLD
ELERLALLIACLCHDIDHRGTTNAFQLQSKTPLAQLYSSEGSVLERHHYAQTVQILQMNE
CNILDQLTRTQYQTVLSHIRDVILATDIAVHLKKVGRIKAMVDQGYDPLSRDHHYLFMCL
LMTSSDLSDQSKDFRNSKAIAENIYREFFSQGDLEKQMGASPMEMMDRDRAAVPKIQLDF
MDTVALPVFEMVAELVPEGRSTFEAITLNRQCWAALDEILVERGNRPVLGLDYLRDDELE
KQVLERVNKKKNQQNKMNCLR
>A0A1S8L4V6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium roseum|TrEMBL
MIHTKRVFKTNMILFCEFAFFLNILNGSSIFKSQKLKFNNEGKFKIVQFTDLHQNDSINL
KTVHFMEKVIDSEKPDFVMLTGDNIDGRYCMNITYKKAIESIVKPMEERKIPWAVVLGNH
DTESIDVKRKDMVKEYTKYQYNMNKLTEENEFNLLVMNSKDSLPIFNMYMLDSGDYSDDG
GYGCIELSQVNWYKETSSGLRKKYKHIIPAIMFFHIPLIQYNEAFEKNNLSGERREKICY
QGKDTGLLKEIQKQGDVKAIFVGHDHTNDFIGKVGDVFLGYGRCTGYDAYDDSNYERGAR
IILLNEKDTSKFKTWETLDKNLK
>A0A1Q9PBI1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Heimdallarchaeota archaeon AB_125|TrEMBL
MDKSVKIVHFSDIHFTPRLQFIKNSYNEAVSVINKTPHDFAVFSGDLTQDGLIDEYELAN
KLRRDIISPKIYWIIGNHDSRSGGFEVWEEKVGLREFHEFSDDILFIGLDSCIPDQDGGR
FGREALDYTKKILMKYGDAKLKLVGFHHHILPIPKTGRERSNAIDAGDMLSVLLDHNVDA
VLTGHKHHPNVYKVEDTIIISAGSVS
>A0A091SVY9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pelecanus crispus|TrEMBL
RLRCLVKQLEKGDINVVDLKKNIEYAASVLEAVYIDETRKLLDTEDELSDIQSDSVPLEV
RDWLASTFTREMGIVKRRPEEKPKFRSIVHAVQAGIFVERMYRRTSSMVGLAYPAEVIVT
FKDVDKWSFDVFALNEASGEHSLKFMMYELFTRYDLLSRFKIPVPNLISFAEALEVGYSK
YKNPYHNLVHAADVTQTVHYIMIHTGIMHWLTELEILAMIFAAAVHDYEHTGTTNNFHIQ
TRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILANLTKDDWR
>A0A7W8ZHX5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pedobacter cryoconitis|TrEMBL
MNKKLYFLLLILFSLVFKHGYAQNQTSFKVIPLGTKGGLDESNLSAYLVAPAGSENFICA
DAGTIRHGIDIAINNQLFRGPADDVLKNKIKGYLISHAHLDHVAGLIMNSPDDSKKNIYA
IPSVTEVLRDKYFTWKAWANFANEGELPRLGKYTYVRLKENKKTDLAGTEMQVTPFLLSH
GPGYESTAFLISHDNTSLLYLGDTGADEIEKNTRLRKLWEQVAPLIIKNQLKAIFIETSF
SNKQPENQLFGHLTPRLLMVELNKLRQLTGQEALQKVSIVITHMKAWDKDEQYLVNELKQ
VNSMDLKLVFPEQGQLLEF
>A0A086Q360|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii VAND|TrEMBL
MVRSLIIDLILATDMKNHFETVSRFRVRRNALDFDLSSEEDFWFAVKIIMKCADLSHCSV
PWSQHFQWCQRLSVEFYDQGDEEVARHLPMSPLCDREKHSEVAKSQLGFMSFVAVPLFEE
LMAIDGTGNIEKYCISVMKTNASHWEALSSAAVPVPLLGEAPSPDVAPPLLHLIDGSGAA
AVHPGSKAAEIANRYASSTVTTLDLTCLVYRTQLNRARRSSQQSGRRVSEGTSA
>A0A136WAW5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Anaerotignum neopropionicum|TrEMBL
MKKRVLSVLLASSMAISLALFTSGCGQKSSAAALWEAGSIRNKIVVISDIHIGIDDQYAE
TVKNRPLLIEFLQKLQRTKDVRELVIDGDFLDEWFLPVDYSSYTDVQQFYKDVIANNQGV
IDELNKVADSGIKLVYIPGNHDMTQENDILQEAIPKIVQIRDAKGLGTYYTGDRNEIVIE
HGHRYDVFSAPDTVTNAELVGNSDTILPAGYFYARYAATWVLEGRPKVEKNLPVVTNVPD
KSDIDQYGAFMYYYILKSVSERMTPNEGLDEKIFDMHMAGFDDAYTYLDFYPAQQADGTI
SAPVLFKNIQRTWDERQKANQVKVPNSFLEAVAGTVDWEYYFRQAKAQHLENLDENVDVV
VFGHTHAPSYRAMDNGKYYINDGTWIDHNTDYPDTTRTFAVITTGDKTTAGLYMYEEDGS
VTDIAASVSGDRGQAAPATNSLENASFDYKAVENYGDDDTQARYVEVSGLTDTTVQEKLN
QALKEFCLAPISSAEKDTNYDIMPVFEMVGGDLLSIRTYNTAYTPGAAYPVSSIRTQLFS
LTTGDKDAGNLWDFIKDKDAFKQLVLDGKFGFAPAGVEGEIPKELKTAVYQKLAQNIDAP
EFATKFYFGDGGNLNVWCEGDNHVTGDYWLFDIPVIELEGLATNQLLSIIENLKNLSN
>A0A2W0C504|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Paenibacillus illinoisensis|TrEMBL
MMEVEFMRLALLGDYHYSSMSHGTEEMKAARVRAYEHMLKAFLEVEADFHISIGDLTHEG
TAQEFGSIFSFLSRSERNFIHVLGNHDTYSIPKHEISKLTGQDRYRAIDTPHAKLIFLDT
TQEMNPADWGGELDEEQLTWLKEELTNSHDKQVLIFGHHPVFDTTARSTLDKLYIRPQDE
LKSIFNNQPEGGIYFCGHNHINSIVKQGKWHYVQTAACLDVPAYRVIEVHEGQVEITHHP
IQGAGLLDDIQSFCCDMPGFGPVAGALGEESDLILSVQSASAAQ
>A0A085GLC0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ewingella americana ATCC 33852|TrEMBL
MRNKMLALILACSASQAYAGFDVVALGVHGGVEEGNLTSYLIRSDDQKLYLGLDAGSVLP
GISKALDKGAFPQVTAENAAPYTPQGAVFRNLIGGYFISHGHLDHLAGLIISSPEDSKKP
IYGTADTIGTLRQHYFNGKVWPNFTDAGSGLRIGTYRLNAPRPAQRFSVGLTGLDGVIYP
LSHGGTASSMILLSRNKESFAYFGDTGPDAVEKSNNLATVWQVLSAEVKAKRLKGIIIET
SYPDDVADGKLFGHLTPEWLLKELKVLETGSGGKGSLDGLSVIISHIKPSLKAGENPEAE
IMRQLQEGNDLGVKFVRMQQGDSLKL
>A0A6N3CDI5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Parabacteroides merdae|TrEMBL
MYKQTLPLFLCILLSACDLIDYHPYDGRLTISERDINGHNIPLIETATKDKDTIRFVLMG
DTQRSYDETEDFVKHINTKKDSIDFIIHGGDYTEFGMKKEYEWAVDILSKLDIPYVGLIG
NHDVIGNGDQVFNKLFGEENFSFIVRDIKFICLNTNAIEYDYSHPVPDFSFLKEELQDST
RHYNRTVVAMHARPGSEQFDNNVKDVFQLYIREFPSLLFCLNAHNHQLQVEDLFDDGIIY
YGCSNIAKRNYLLFTLTPDNYTYEVIDF
>A0A1C3K6D3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Orrella dioscoreae|TrEMBL
MKFIHLTDTHLVADGGELYGTNPKQRLRQAIAHLLARQPDAEAVVVTGDLTHHGHAQAYA
HLRECLSALTLPVYPILGNHDSRVVFKEYFPGVAQDEHGFIQYSVDFGSHLALFLDTNEP
GVHWGVYCETRAAWLRARLAETDRPVLLFMHHPFFPIGIPSMDFLSLRDPAPLLAAIAGH
EARIRHVFFGHIHRPICGQYRGMGYSTLRGTNHQVALDLHGSAQCIIGSHEQPQYAVVQV
DAEQLLIHVEDYLDCDRQFLLHEMRDGAAGLK
>B7PPC8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ixodes scapularis|TrEMBL
MNLDAENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPVLNEYFFDRHPGVFG
QILNYYRTGKLHYPTDVCGPLFEEELEFWGLDANQVEPCCWMTYTQHRDTQETLAVLDRL
DLDTDKPSDEEIARKFGMEEEYLAGTLSCWQRVKPKIWSLFDEPYSSTAAKVIGVMSVFF
ICVSILSFCLKTHPNMRVPVIKNITVHTSDSSVAWTLDKMQTNPHDAFFYIECVCNAWFT
FEIIIRFVASPSKLDFVRGAVNIIDFTATLSFYIDFTLQKLASHLENADILEFFSIIRIM
RLFKLTRHSAGLKILIQTFKASAGELILLVFFLVLGIVIFASLVYYAERIQSNPENDFNS
IPLGLWWALVTMTTVGYGDMVPKTYAGMFVGALCALAGVLTIALPVPVIVSNFAMFYSHT
QARAKLPKKRRRVVPIEVPRGPHRRPQDLKNPKDACKPGEPERAESVPSPRRAL
>A0A0A8TMU2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acinetobacter bereziniae|TrEMBL
MQSKILQQTDKDKVIIQITDTHLMDKPDAKFVGINPEESFHAVMEDVQQRFPNADLILHT
GDLAQAAYPETYARYLNYMRGFGIDFYHIPGNHDNLSFFPFHVPEPEPTVIELDQWCIIL
LNSTVSGRTDGKIQPEQLVRLKQRLEQLRDKFVIVACHHNPFEMHSKWLDQHKLKNADEL
KAVLEPFNNIKLLLHGHVHQESYNEWNGIQFISTPATCVQFKPLSQEFSFDPIAPGYRCL
HLKANGEFETFVHRLDHFNVTINEEISGY
>K8B5A4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cronobacter dublinensis 1210|TrEMBL
MLIAQISDIHAAPDNDNLARFDNALAWLAPLTPDLLVISGDLTDDGWRDGYSQIAARLEA
FPCRKLILPGNADHLDALRATWSATFWTGADGPLHAVVDLPGLRAIGLDSTLEACAAGSV
AAHLSWLSQQLDEAQGRQTLLFMHHHVFASGIPSMDAIMCRDHDALAALLRQHPARPLAI
ATGHVHRPAAGTLAGIPAYICGAVCPANPLWLGASHVPFVYDPPALMVHRVENGALASHF
IAVSPVTAA
>A0A157S826|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bordetella ansorpii|TrEMBL
MLIAQITDLHIRMPGQKAYRIVETDQFLPPAVSALNALDPAPDVVMISGDLTDFGRAAEY
LHLKAMLDRLAAPYYLLPGNHDARAELQSVFDSHTYLGGVDGFVQYTVEDYPLRIVVLDT
VVPMQSHGALCERRLDWLAERLAEQPERPTVIVMHHPPFITGIGHMDAIGLLSGAERFEA
IVRQHDNVERIMCGHLHRTIFRRYAGTVASTAPSTAHQVALDLRPAGPSAFRMEPPGFHL
HEWRNGALVTHHAYIGDYPGPFPFHEGGELIDE
>A0A3L8SLZ2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chloebia gouldiae|TrEMBL
MAGLWSLLKQLERGEASVVDLKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDSLPS
EVRDWLASTFTRQMGMMLKRTEEKPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVI
GVLKNVDKWSFDVFALNDASGDHALKFIFYELLTRYDLINRFKIPISALVSFVEALEVGY
SKHKNPYHNLMHAADVSQTVHCLLFKTGTVRWLTELEIFAMIFAAAIHDYEHTGTTNNFH
IQTRSDLAILYNDRSVLENHHVSAAYRLLQDDEEMNILSNLSKDDWR
>A0A7R9NX24|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Timema tahoe|TrEMBL
MGPEMRLADEDDELSEVQPDAVPPEVREWLASTFTRQLATTRRKADEKPKFRSVAHAIRA
GIFVDRIYRRVSNTALMQFPPEVVKVLKTLDDWSFDVFALSESATSQPVKYLGYDLLNRY
GMIHKFKVPPVTLETFLNKVEEGYCRHRNPYHNNLHAADVAQTVHYMLCQTGLMNWLTDL
EIFATLVAAIIHDYEHTGTTNNFHVMSGTDTALLYNDRAVLENHHISASFRVMREEECNI
LQNLSREEFREFRTLVIDMVLATDMSFHFQQLKNMRNLLSLAEPSVDKSKALSLVLHCCD
ISHPAKRWDLHHRWTMQLLEEFFIQGDKERELGLPFSPLCDRNNTLVAESQIGFIEFIVE
PSMGVCSDMLESILGPIHSSCKPQIGEGARESISEEGELDRTKNGKGINSVVNL
>A0A517QDU9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia panareensis|TrEMBL
MPVHLPAQNRRQFLFTLGAGFLTCSAGAFAKDAQQSDIIYLLNDTHIGEKHPENSPVPSH
LRKVVSELVSLEQKPACVLINGDLALRDGQPGDYRHFAKLIRPLREAKIDTHLTLGNHDE
RDVFYTVMQEEQPETPPVKSKHISVVQTQYANFFLLDSLHKTMVTQGTLGAEQRSWLANA
LDAHADQPAIIMTHHNPRLGGDPNHFPGGLTDSVELWEILAPRKQVKAYIHGHIHDRGNA
EHKGIHIINTPATSYVANPKQSTTGWTVAKLSPEGITLTTRTSDDQHPWNHQSKTLTWR
>A0A8F3DSQ1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ferrovum myxofaciens|TrEMBL
MKLHILSDLHLEFADLQVPYTDADVVVLAGDIHKGERGIEWARFAFPDQKIVFVAGNHEF
YGKHRQDTIDKMRLAAKENDVHFLDDESVVIDGVRFLGATLWTDFLLFGPGERPWCMNDA
QNVMNDFRVISDDGKVFSPTASARLHKTSLEWLTRELQTPFKGKTVVVTHHLPSFKSVAE
RFQKSAMSAAFASNLDHLMGEDRACLWIHGHTHDTMDYEVMGTRVICNPRGYVTSGSQEN
MDFDAEFLTRL
>A0A1C6HXH3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Anaerotruncus sp|TrEMBL
MLRPITFAHISDTHIRKSYQDTGMDAIFAAAPSPAENLRRALTCIAAAKPSFLLITGDLI
HEGQTEDYALLADILREEIPEIPAVCCLGNHDRKAAFRQGYLKEAPSSEPYLAVTEIDGL
RVICLDSAVEGKENGTISESQLDWLARQVQQPAPRGSVLCFHHPIMDEGGMVPGVEVSPR
LQQIVKESDIAAIFCGHTHQNSLSLVGGKPQLVADSLAFGFSVDGTGLHFTTQTCYSLVT
VSQNGVKSEVHPNTPVAASVADISIQQLQAMMKD
>A0A1L3LVY7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sinorhizobium americanum|TrEMBL
MKIVQISDTHLSPSKTHFNDNWEPVARWIETVGADLVVHTGDLTIDGADQEEDIVFSMEL
MRKLSVPVLIVPGNHDVGHLPGSDQPVDAARLDRWRRLVGPDYWVSDHGNWRLIGLNSLL
LGYGDEEEERQFQWLEQTLATRADRRVAIFAHKPLFVDEPLEGDTGYWSVKPQQRQRLYE
LMAENDVALHASGHLHWAWRGQHAGTDLLWAPPTSFIVDTLEREMPGERLVGAVLHHLEG
SIDSEIVAIPGLTRYVIDPVIEEIYPRHARKLAEAAQ
>A0A379K272|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas oleovorans|TrEMBL
MPSLPTQSTDSSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIERVLQEQPQIDLILAT
GDLSQDGSEASYQRFRQLTSAIDAPTRWLAGNHDEIPPMQAACQGSELLEPVIDLGAWRI
VMLDSSIPGAVPGFLADGQLELLERALSEAPQRHHLICLHHHPVAIGCKWMEPIGLRNPD
ALFAVLDRYPQARTVLWGHIHQEFDQQRGNLRLLASPSTCVQFAPGSEEFQVDSEAPGYR
WLRLHADGKLDTGVSRVTGITFEIDYSVKGY
>A0A192C606|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli O25b:H4|TrEMBL
MRQDAEVIMKLTDADNAADGIFFPALEQNMMGAVLINENDEVMFFNPAAEKLWGYKREEV
IGNNIDMLIPRDLRPAHPQYIRHNREGGKARVEGMSRELQLEKKDGSKIWTRFALSKVSA
EGKVYYLALVRDASVEMAQKEQTRQLIIAVDHLDRPVIVLDPERHIVQCNRAFTEMFGYC
INEASGMQPDTLLNIPEFPADNRIRLQQLLWKTARDQDEFLLLTRTGEKIWIKASISPVY
DVLAHLQNLVMTFSDITEERQIRQLEGNILAAMCSSPPFHEMGEIICRNIESVLNESHVS
LFALRNGMPIHWASSSHGAEVQNAQSWSATIRQRDGAPAGILQIKTSSGAETSAFIERVA
DISQHMAALALEQEKSRQHIEQLIQFDPMTGLPNRNNLHNYLDDLVDKAVSPVVYLIGVD
HIQDVIDSLGYAWADQALLEVVNRFREKLKPDQYLCRIEGASFVLVSLENDVSNITQIAD
ELRNVVSKPIMIDDKPFPLTLSIGISYDVGKNRDYLLSTAHNAMDFIRKNGGNGWQFFSP
AMNEMVKERLVLGAALKEAISNNQLKLVYQPQIFAETGELYGIEALARWYDPLHGHVPPS
RFIPLAEEIGEIENIGRWVIAEACRQLAEWRSQNIHIPALSVNLSALHFRSNQLPNQVSD
AMHAWGIDGHQLTVEITESMMMEHDTEIFKRIQILRDMGIGLSVDDFGTGFSGLSRLVSL
PVTEIKIDKSFVDRCLTEKRILALLEAITSIGQSLNLTVVAEGVETKEQFEMLRKIHCRV
IQGYFFSRPLPAEEIPGWMSSVLPLKI
>A0A378IT64|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Legionella feeleii|TrEMBL
MRIIHISDLHFGMHQDHIKEAFLAELALLKPAVIIISGDLTQRAKAYQFELLQSFLRCLP
GEVLVVPGNHDIPLYNLLGRIFYPFKAYKKYIAKHFNAQLSTDSLTILGINSVDPYQIKD
GQLSAKVIKKIKQYFRLEKKAVNILFFHHNFDHIEGLHKPLENEMEFLSFLRGSDIDIVC
TGHLHYAHVGLIRKDNMKPCVILHAGTLLCTRSKDGLNSYFVIDLEGDQCAIDWRVFAKG
QFLSRKNYSIKLSEVNAQLSS
>A0A086QWN0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii MAS|TrEMBL
MNASSKSMRIGFPNGSPGVGDPGMPSPVLPLCQTASHALGNARSQASEGRTDGASDRSIS
ELEKESCQRGHRLEAREASEILAAESAQEEHRSCARKPRASRVEVDTLAESPERPSQAYV
PTESLGLGPRRTVPLSSAGSSASAGSWISSGESVREETRQIRGRDAANKCSAAELSVSVE
RSCGHHEGTDTATQCVAARPEALCAAFLPAPSPGVTVDSAAAAVGPHCAAEVPVGADRRR
RLFAAPFSALPQTDACSRGSATPPSLFSRQPFDTVRSSSSLRDGGNAWTRLLDGCSAHPT
SSSSSVSPPVLGSIRTLQQSLPSSDDDTTSARTDTSLTPAKQVWLLPLHGHSLSQSSSSS
FREFRVTLGSLTGFRSSDSRTSASGSERRRSKSRGKPQGRSGSLGRDNRRKSELSGRDES
LSWIARRWWTRDEDSRWSDSRVRGSVALRAESTSDSRCENNSCATWLCRVVRRLPVAPAQ
TFCDEDEKRYTEGVLRFSRRRTIPVAVAVVIVSFLYTVPFVLHALQEFVQTPSADRKVFV
FFSSRAPPRSPVAAGAAHDAQLDVSAADSALQDVGGKDAFFVVASLVFWLLSLASVLVFA
FFAVFGALFVRIEKILCVLTAVNFSALALAECFQALRISSCPPSLFPEQAAAEGGSDADR
CAQVHSGLTPELLIIQTFFLIVLDFAFCVRLRISQWLHLCAVSLLLSLAFVYSILLPLPA
YLIASLWGQAVIGGFVLGSLHLAALTLETERRRVFLHFEVAKARVAELQERAQTDKHHGK
VAVFGLIHTLKQMDACMNELQNLAPEAADVLFQLDALRVQCLDIATSSENFYAVNMNALP
TDVRDLLQLETRNAFDGTTFRDTQVLLRDSLSPRKGVLLDLSLGPACGGVSRERRASCSA
AVSSTSSRESDRREAIARDPDLTETERRDAERRGMERKATDDRQKKARFLVVPQLVEHEL
LCHVGILWSLDLFKLDKECNGNALLHVGYQLLAPLLAAGYLTCSREVVLDFLYSLQCLYI
DTPYHNQLHAASVAHLAFSICHFLDLFAPLENAPGDAAASQPVFAQYLSLAIAALGHDAG
HPGRSNAFLVQTSSTLSVVYNDRSILENYHACLTFYTLSHRKSNIFRGKTVTQYRDVRKK
AIELILSTDMSLHFEFLTRVAARRENPDFNFVDREEDRALVLSLAIKVADLGHCALDWEA
HTLWSARLKEEFLAQGDEELRLGLPVSPLCDRTQQGQLARSQANFIEFLFLPLAQHLAAV
APDDRFEATVVTRARQNISMWERAQDEVDQASAK
>A0A8B6C953|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mytilus galloprovincialis|TrEMBL
MSNQKPPKTRDVSPELVTHFLNENPEFLDRYVTTHVSEDKIRQWSLRKGSKNVHTRQHNL
NGELLREKKSSKWKTCVQSSKWKVLHEMTRDISYQTDRLQILAELAQCAVDCKF
>A0A517XI64|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia maris|TrEMBL
MPVHLPAQNRRQFLFTLGAGFVTCSTGLLAAEQKTQQSDIVYLLNDTHIGEKHPPKSPIP
THLREIVTELVELPQKPACVLINGDLALRDGQPGDYRHFASLIQPLQEAKIDTHLTLGNH
DERDVFYEVMQEQRPSAPPVKSRHISVVQTKFANFFLLDSLHKTMVTQGTLGKEQRSWLA
NALDAHADKPAIIVTHHNPRLGGDPVHFPGGLTDSEELWELLVSRPQVKAYIHGHIHDRG
NAQHKGIHILNTPATSYVANPDHSTTGWTIAQLTPTGVTLTTRTNIEDHAWNRQTKTLTW
R
>B8CIV3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Shewanella piezotolerans (strain WP3 / JCM 13877)|TrEMBL
MVQVTDPHLFADPEAQLLGVNTAQSLNAVLNTIAAVDYPAHFMLATGDISQDYSNESYHS
FVDAIAPLKIPCHYLPGNHDDPRIMNLHMQGDNVHGQKRVLAGNWQIIMLDSTVRGRPGG
HMSEAELTLIDRAIEAEPNRHTLLVMHHNPVLAGCAWLDQHCMDNGSDFIQQVSRYRQVK
GLLWGHIHQSVDTVHLGPNGPVKLMATPSTCIQFKPKSPYFALDALQPGYRLLELKSDGS
ILTNVYRVPGENFSPDNEAGGY
>A0A1J5RER8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|mine drainage metagenome|TrEMBL
MRLCVMSDLHLEYERQGRGSLPLGPDLDGLQGIDVVILAGDVDEGLAGLDYAGGLARRWG
CPVLYVPGNHEYYGHDFPSLQAVLRSAGKGGVVVLDRRSFVFQGWRFVGCTLWTDYELDG
QADKSMRLAEQRLGDHRRIGWDGGGNFSPRHACEEFRASQAWLVAELTKHAPGRAIVITH
HAPLPEAIAPHFRNGDLNAAFASDLRSLIRELRPALWIYGHTHHDIDVRIGETRVVARQR
GYWGQDNVTDFRPLLIDLPE
>A0A1J5U176|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|mine drainage metagenome|TrEMBL
MRIHVLSDLHIEIAAYQPQPVECDVVVLAGDIGNHVQGMEWGRHSWPAKEILYVPGNHEF
YRLGRVETLRQMRVRANELGVHLLDNDEVVIAGIRFLGSTLWTDFDLFGEELKKAAMAEG
KKYLNDFRLIRERFRMFSPARSAQLHKTSRAWLAAKLQEPFPGKTVVVTHHLPSARSVAE
RYRASLTSACFASNLDELMGASALWIHGHTHDSFDYVLHGTRVVCNPRGYCRNPEKPENL
EFDPGLVVEV
>A0A093BTT5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pterocles gutturalis|TrEMBL
SRLRSLVKQLERGEASVVDLKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDSVPSE
VRDWLASTFTRQMGMMLKRTEEKPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIG
VLKNVDKWSFDVFALNDASGDHALKFIFYELLTRYDLINRFKIPISALVSFVEALEVGYS
KHKNPYHNLMHAADVTQTVHYLLFKTGIVHWLTELEIFAMIFAAAIHDYEHTGTTNNFHI
QTRSDSAILYNDRSVLENHHVSAAYRLLQDDEEMNILSNLSKDDWR
>A0A162FBE0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Methanobrevibacter curvatus|TrEMBL
MTLITHISDIHFGSSAFNEEIYLKFVDEINNSKTDFIILTGDLTDNGYYSSFLKIKEYLN
MFEAPLLSIPGNHDARNVGFKVFEDEIGERNWARKISDDEILIVGLDSSEPDLNNGNIGR
FQQLWLEDLLQTTIDDSIFSIVALHHHLIPIPNTGRERNELLDAGDVLKSLVDKKVNLVI
SGHKHVPYIWKLEDSYFISAGSLSSNKLRGKILNSYNTYDISKNNVEVLLNQIDGSKIFL
ASFERD
>A0A2U3Q399|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bradyrhizobium vignae|TrEMBL
MPFKFIHLTDTHLANPGLTLYGLDPRARLDAAIADINKHQSDAAFAVVTGDLTHWGEAES
YANFAEAMAALKIPYIAMVGNHDRRVTCLDALKAAPRDANGFVQGTRTTEHGLFVFLDTL
DETSHAGEMCAKRLGWLESTLAAAPADQEFVVFMHHPPFPVGVHAMDEIALKQSAEFADV
IAPYRARIRHLFFGHVHRPIFGSYGKIPFSTLRGTNHQVWFELDAAATEHLASHEPPAYG
VVLIDQEHLVVHSHDFLDQSLRFPFEPPAGVDGRDYALNFRAP
>A0A671VF33|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sparus aurata|TrEMBL
MESPTKEIEEFESTALKYLQPEQIEKIWLRLRGLRKYKKTSQRLRCLVKQLERGEASLTD
LKKNLEYAASVLESVYIEETRRLVDTEDELSDIQSESVPSEVRDWLASTFTRQMGLMLRR
NEEKPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYPPSVISVLKNVDKWSFDVFALNEAS
GEHALKFIFYELLTRYDLISRFKIPISAVMSFVEALEVGYSKHKNPYHNLMHAADVTQTV
HYLLLKTGAHFSLNFSVHYSSARDYCFLFHFGRSDTAILYNDRSVLESHHVSAAYRLLQE
DDEMNILYNLSKDDWRSLRALVVEMVLATDMSCHFQQVKAMKNFLQQPEGLDKPKALSLL
LHTADISHPAKSWDLHHRWTTSLLEEFFRQGDKEAELGLPFSPLCDRKSTMVAQSQIGFI
DFIVVPTFTVLTDMMERIVTPLIDEASHSGFAGFRRSSLNSITSDEAKRHSVKSSDSSSS
GQSSLLTVDIKNFKALWNEEVYQNRERWKAQACKDEHWPKGHQYMGWPISLADMIKYVSL
GVLLPDMPTYENSSLRDNKAGKDVRIIHNH
>A0A5P9D269|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Labrenzia sp. THAF82|TrEMBL
MTLIAHMTDLHLRPRGLACYRVSDTNMFAERAIRSLKSLDPQPDALVITGDLTDRSDPRE
YAVARELLSRLDMPVFLLPGNHDSTSGMRREMSSFPGISETGDGKICYTAKIGNVQLIAL
DSHLPGSPKGELGPWQLAWLDSRLKETQVPTLLALHHPPALSGIVHMDNMGLVDADALAE
VIAPHAHVERIICGHLHRPIIASFAGKVMTLAPSTGHQVVLDLTENGPALFNFEPPAYFL
HYHSEATGVVSHMAYVEAFPGPHHFFADEGVVWPGDEA
>A0A2X2MB73|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces griseus|TrEMBL
MALSVAHLSDPHLTTGAGAAAPTAGLRAALRRVLSLDPLPDCVVITGDLTERGEPGEYAA
LREEIGAFPLPLLLVTGNHDVPEAVVDAFGGTRFLGGGTLTTYAVEYPEFTAVVLDSWVS
GAPGGRLGAEQLSRLDRDLSRRPGVPALVCLHHPPVPVGIPFLDAMRLVDGPALAEVVAA
HPRVVRVLAGHVHRPVTAPFAGSTVAVAPSTYRQSGLALREGVPGYPDEPAAFLLHVLPE
GPPGTDWVTHTVPVGDGSPAGPVTRAAPPARP
>A0A5P9C378|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. THAF187a|TrEMBL
MPSLPIPSADSSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIEQVQQEQPQIDLILAT
GDLSQDGSVASYERFRQLTAPIGAPCRWLAGNHDETPPMQAVCKDSELLQPVIDLGAWRI
IMLDSSIPGAVPGFLADSQLELLQRALDEAPQRHHLVCLHHHPVAIGCKWMDPIGLRNPD
ALFAILDRHPQARAVLWGHIHQEFDQPRGNLRLLASPSTCVQFAPGSEEFQVGSEAPGYR
WLRLHADGTLDTGISRVTGIHFEVDYSVKGY
>A0A8H8XB32|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bathymodiolus thermophilus thioautotrophic gill symbiont|TrEMBL
MKHFIQISDCHIDDAEQSMGVNTHQNLAHIIDKIAPMQSDALLISGDLTHHGTLTSYKKL
KELLAPVQSNIFVLAGNHDNPHNLAAVFSACLFNTLSMGVWDIISVDSVQAKKTSGYLTK
DVLLELDQQLANSQAKYILVVLHHPIVPMCSTWDDTLSLENPQDLFTVLDKHLKIQAVLF
GHAHEAAEFERNGLKIIACPSTAVQFTDEKRIGFNHYTLNNNGHLEYKTQWI
>A0A0D8Y972|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Dictyocaulus viviparus|TrEMBL
MIYLGLLYVGLVVAELERSGSSTEVFARQRRLNSFLLDVAKSIFHDIVSMDTVIIKVMNF
AAKLVDADRASLFLVDNKNQELYARIFDVGREAEQLDQFVKEGNKEIRFSMKRGIAGHVA
TTGEGLNIENAYEDYRFNPEIDTKTGYTTKTILCMPIFIRGNVIGVVQMVNKHDGVFTKS
DEDSFEVFAVYCGLALHHAKLYDKIRRSEQKYRVALEVLAYHSVCNKDEVAKIQKMEIKD
RVEELETFHFNYLRMSELEKPLYAISMFKTLFKDQFRYDRDELIRFVLTVRKNYRRVAYH
NWAHGWSVAHTMFVVLIQSSKKIFTTHEALALYVSCLCHDLDHRGKNNAYMKSMMTPLAS
IYTTSVMEHHHFNQTVTILQQVCLCSIFII
>A0A1B2A936|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Tsuneonella dongtanensis|TrEMBL
MLIAQLTDIHIGFDPDEMPEELNLRRFRATLARLLGGPNRPDMLILSGDITDNGDLESFE
DAAALVSGCPFPVWPMVGNHDSREGLFHAFPHIKGEGGFVHYAVDADGLRILLLDTLEPG
RHGGAFCEARARWLAAELAAHPDTPTLIFMHHPPVVSGIDWMDPAATEDWIVRFGDVVEG
HEQIRGIHCGHLHRPIHSTFRGIPLSVTGSCAPLVAMDLRPVDRDHPDGRDLITTEPPSY
ALHRWDGSSIVSHYEDVSGWHALAHYTDKLQPMIHDMFGERD
>C5BG82|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Edwardsiella ictaluri (strain 93-146)|TrEMBL
MMQRMWRRWVAGGALLCGLTMCPAQAAFELVALGSGGGLSGDNLNAYLIRHERDERYVAL
DAGSTLPGIARALALGAFPSVNSERAAPWTPQGYVLRELIAAYFISHPHLDHVAGLLLAA
PEDSHKPIYTLADSADTLRNHYFNWKSWPNFSDAGQGQRLGTYRIYSVRPEQRFTLGVSG
LRGVVYPLSHGGETSSMILLEREGEFVAYFGDTGADRVENSQRLDHIWRRLGPLVVSKAL
KGIIIETSFSDETPETQLFGHLTPALLNQEMINLSRYSGGEAALAGLPVVISHIKPSLRA
GVAAEQQIMAQLVAGNRSGVAFRYLRQGERARFAGGEE
>A0A433E595|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces sp. NP10|TrEMBL
MLLAQISDLHLDGSDRATDRADRVMGYLRALPRPVDALLVTGDIADHAAEAEYEEAVRLL
DAPFPVLACPGNHDARPAYRKAFLGEAPDTAPVNRVHHIAGTAVLMCDATIPGRDEGRLD
AETLAWIDTTLGALPDGVPALIAFHQPPVELHHPLPDAGMLQEPERLAALLDAHPRVVAV
LTGHAHTAAASTFAGRPLIVGPAVTWTLRLPWEGDRPADRDQPPGLAFHILGEDRRLTTH
FRVVL
>A0A0B1SZF4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oesophagostomum dentatum|TrEMBL
MAAELLVQGSQLLISEEEVRKLTNETIKDWRYWSPDFDRFTFSPRSIGDGDAYMSASMTM
FNDLGFTDRYRINKRKLAAFLLRVARGYREVPYHNWSHAFSVAHFCWISLRTPAVLHGLH
ELERLALLIACLCHDIDHRGTTNTFQLQSRTPLAQLYSSEGSVLERHHYAQTVQILQMNE
CNILDQLTRTQYQTVLSHIRDVILATDIAVHLGKVSRIKAMVDQGYDPKSPDHHYLFMCL
LMTSSDLSDQSKDFRNSKAIAVSIVARFTFI
>A7AS42|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Babesia bovis|TrEMBL
MGKDLLCSVVEVERFLKDHDADPSITEAFKKVKYAVYDTQIKSMGLQACKLSSSQSSAQW
KNSKAEDVFSSLVRNLFCGCIHNADGIVHDDDTLLSCSSSSECKYTEEVSENGNQITPRK
GWLISGSRRDKNINYDSDEECAKYMAQLGKNWNMDFFAMSNFKFVLRSGPVVAVGHQLID
PVGDKIHPDFNKLITPVLNSIQDVYLPNPYHNALHGACVAHMSCVLLKALSLEQYLTPLE
QFAYLIAALGHDAGHPGKTNAFLRSTQNPLALIYNDASILENYHASLVCHIIRAKEDFFG
LFNQQDWEIIRKRIIQLVLATDMMTHFTHVNNVKERRLSGTFDYVNNPEDLWFCLVLLVK
TADIGHNFLPWCEHLPWTNALFDEFHMQGDEERLLSLPLLLFFDRTRSADIPDSQLGFFQ
GFTSPLIDELTFINTNSTYLNDFLNANAHDNLEHWKKNSKRQLVEIVIDLEKSEEVFEIK
DATVM
>A0A1C5RCL1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Collinsella sp|TrEMBL
MRVLHLSDIHYSLEAKDARRGADGCGDNAHGAVAEVGDRSLSLPAAEFYPAMVDRLGDVL
PAFEACLREGLAADDAGERVGAIVLTGDFVERGGAAAYRAVGEAVHRVCREVLGAVVPCI
VTPGNHDDRAALRAGWPGALPGLGGEPLLYTCEVAGSRLISFDTSEPGHANGYVDAERLA
WLRGELETAASRGQMALVCTHHHMDPSQTDMPVLPGAEELLELLRRPGVAVLNGHTHHQA
HRVYEGVECHTADATSFQADPCDVHPAGGAPVRAVRFRRLSGYNVYDVRDRRIVRACAVT
YDGGEVLGDMLLG
>A0A0M3JZW7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Anisakis simplex|TrEMBL
LISTFISQIIISNSDKYTFKSYEETFSNFRLRYILHQLNSGQLPLEDLKKNIEYAALVLE
TAYMDETRRICDEDDDLAEVTSESVPDEVREWLAATFTRQNVPSKREKPKFKSVANAIRT
GIFFDKMFRKSQAVFAPIPPEIAALMRNVDSWSFDPFKVNEVSDGHALKYVGFELFNRYG
FLERFKIPYQTLENYLLALEAGYSKHNNPYHNIVHAADVTQSSHFMLSQTGLASSLTDLD
LLAVIFGALIHDYEHTGHTNNFHIQSGSNFAMLYNDRSVLENHHVSACFRLLKDGDRNIL
ERLTKEEYRCEFFHK
>A0A8C7AQH1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Neovison vison|TrEMBL
MDDHVTIRKKHLQRPIFRLRCLVKQLEKGDVNVVDLKKNIEYAASVLEAVYIDETRRLLD
TEDELSDIQTDSVPSEVRDWLASTFTRKMGMMKKKSEEKPKFRSIVHAVQAGIFVERMYR
KSYHMVGLVYPEAVIVTLKDVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIP
VSCLISFAEGLEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMSDVALLYNDRSVLEN
HHVSAAYRLMQEEEMNVLINLSKDDWRDLRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPE
GIDKAKTMSLILHAADISHPAKSWQLHHRWTMALMEEFFLQGDKEAELGLPFSPLCDRKS
TMVAQSQIGFIDFIVEPTFSLLTDSTEKIITPLIEEASKTDTSSYGASSLSTFILHSVDL
FRRSNMKGTMNDGTYSPDYSLTSVDLQSFKNNLVDIIQQNKERWKELAAQGEPDLHKNSE
DLVNTEEKRADAHS
>A0A157SER3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bordetella trematum|TrEMBL
MPAMKFIHLTDTHLIADGGELYGTNPKTRLRQAVQHILAHQADAQAVVITGDLTHYGHAP
AYAHLRECLAPLPMPVHLILGNHDNRLVFQQAFAGTPQDDAGFVQYARDFGPYRALFLDT
NEPGVSWGVFCTRRAAWLREQLQGSPQPVLLFMHHPFFPIGIPSMDAISLRDTAAFMAAI
DGHEHRIRQVFFGHIHRPICGVFRGMPYSTLRGTNHQVALDLGGDAQVIVGAHEPPQYGV
VLLSPDQVLIHAEDYLDAGGRYLLHEMHPQQAA
>A0A402E1F3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Helicobacter pylori|TrEMBL
MQVYHLSHIDLDGYACQLVSKQFFKNIQCYNANYGREVSARIYEILNAIAQSKESEFLIL
ISDLNLNLNEAQYLQDKIQEHRLQNRNIQIQLLDHHISGKEVADSFHWYFLDTNRCATKI
VYEFLKKHYAILEPKNTAWLEPLVEMVNSVDIWDTQGYGFELGKVCMRMINQSSELNRFM
FDDENRDYKLKLLEEVKNYLFLENAPVAYDNDLFKLKKIALGGDPDTETMDNISSNAQTH
LLSLKKHDCSVYYQDKKGFLSYSMGGISVLANLFLTQNPDFDFYIDVNSKGNVSLRANGN
CDVCELSQMCFNGGGHRNASGGKIDGFKESFNYRDIKEQVEEIFNNA
>A0A378YHG9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pandoraea pnomenusa|TrEMBL
MLFAQISDLHIKRPGKLAYRRVDTAAYLTRCVARLNTLAPRPDFVVLTGDLVDFGAREEY
DHLRSLLAPLEIPYYLVIGNHDGRDALREVFPEHTYLGNPGEFVQYAATFGPMRLVALDT
QDPPNGGGRLCDARLQWLEATLAADTGTPTVIAMHHPPFVCGIEHMDVQSLDAADAAKLA
AVVRRFDNVERVICGHVHRPIHTRFAGTIASVCPSPAHQVALDLRDGGPSAWVLDPPAFE
LHRFTPSTGLVSHLAFVDDAGGAHPFYDASGALID
>A0A7N8YCB7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mastacembelus armatus|TrEMBL
MRGMLKQLEEKDVDFEEIKKNLEYTAALLEAVYLDGTRQCLESEDDLQQLQSDGVPSEVT
DWLASTFTQRVRRPVRRSDEKPKFRSIVHAVQAGIFVERMFKRAYTAAMPDQPVAVINCL
RDVDRWNFDVFAVNSASSDHALQTLFFELITRYELNSRFKIPISCLTEFLSALERGYCKY
NNPYHNHVHAADVTQTLHCLLLRSGLVHWLTELEVMASLFAAAIHDYEHTGTTNNFHIHT
KSEFALIYNDRSVQESHHLSAAFQLLQDHQMNIFMNLTREEWMELRSLVIEMVLSTDMSS
HLLQVKAMKSCLEQQERIDKPKALSLLLHTADISHPSKPWALHSRWTKALMEEFFRQGDR
EAELGLPFSPLCDRKSTLVAESQIGFIDFIVYPTFSLLTDMAEKIVIPLGKKNEQRHS
>A0A379LMQ2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Psychrobacter phenylpyruvicus|TrEMBL
MSIPQGSVDLINYPPTQITTEDGVVNILQLTDPHLYLDPNTQTAGINNYQSFTACLQQAL
NEDIRCDLILLSGDLVNEVKPEIYQKIYQLLAQTGIAFVCIAGNHDVTDELDTHLPFSQR
RFVPHKPNPMLLSNHCLVLNEWRLLLIDSSVPGKIYGAVGNKNLNWLAQNLANSHHPVII
AMHHHVLPMDSTWIDQHIAQDAEAFWQLVDNHSTVKAVVSGHVHQNFESQRAGVKVYATP
STCYQFKPKSDDFAIDDQAVPGYRWLSLDKQGTIKSWITRLANKNA
>A0A086L3S2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii p89|TrEMBL
DLLHHFAATAQVEIPGEILMGFAVALYKNYEQNPYHNFFHALNVAQVCCLLMALPDVAAR
FQPLDYFVLSVAALGHDLGHPGANNLFVNRNDCLPSRLYQNRSVLENYHAALLFQILRHP
RFNVFCSIPPQAFSACRQRIISAILWTDMAKHFDMVAQLKAKIEDEMVLTEGIIVTLQKP
YLEGLLLHASDISNPLLSFDLSFDWAVRACDEFFQQNKLEEKLGQPPHMPTFAAFDLYNV
AKCQVNFI
>A0A518GDU9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Aureliella helgolandensis|TrEMBL
MPIHRNPTSRRDFVKVTAALGGVATILASTPAAFAAASQPTRIALLSDTHIPSSPDTAAR
GVNMTDNLRRTIADICKLKAPPSHLIINGDCAYLKGLPDDYANFAACLAPLDETQIALHV
TMGNHDDRQSLYGALSNQRPADNPAVLSKHISVIETPHANFFLLDSLFRVNVVTGELGAE
QIRWLAHELDTRQDKPAVVMTHHNPQFTAPTDGKQWTGISDTQELFQVLDARKHVRAFLY
GHSHNWTYSSRGHFQLINLPPVAYVFSPDRPNGWVSAELTEDAMSLELHTFDSQHPQSGE
RLEVPLKA
>A0A3N6HTQ7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces sp. ADI97-07|TrEMBL
MTVSIAHLSDPHLKTGSLAGAPAEGLYRALGRVLTIDPAPDCVVITGDLVDRGGAEDYRA
LREVIERFPLPLHLVAGNHDEPRALLDEFAGTRFMGDGAEARYAVDYAAFTLVTLDSTVP
ASPGGHLGATQLRWLDEVLRRRPQVPAIICLHHPPMAVGIPYLDGMGLDDGKDLADVLAR
HGNVVRVLAGHVHRSITAPFAGSTLAIAPSTHLQSGLALQGGIPDFVPEPTSFLLHLLAG
SSWVTHSVAVSHAAGPVATF
>A0A091V241|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nipponia nippon|TrEMBL
RLRYMVKQLETGEVNVEELKRNLEYAASLLEAVYIDETRQMLDTEDELREMGSDAAVPSE
VRDWLAATFTQQARAKGRRAEEKPKFRSIVHAVQAGIFVERMFRRTYTAVGPSYSTSVLN
CLKSLDLWCFDVFALNRVTDDHSLRTIVFELFTRHNLNSRFKIPSVFLTTLLDALEAGYG
KYRNPYHNQVHAADVTQTVHCFLLRTGMLHYLTEIEVLAIIFAAAIHDYEHTGTTNSFHI
QTKSDCAILYNDRSVLENHHISAVFRMMQDDEMNIFVNLTKDEFVELRALVIEMVLATDM
SCHFQQVKSMKTSLQQLERIDKSKVLSLLLHAADISHPTKQWSVHSRWTKALMEEFFRQG
DKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKMVLPLAEDGTKAK
>M5RQT7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodopirellula maiorica SM1|TrEMBL
MIPEVAQLNRASSLVRIPPAEGVPISPRVRRIIDSPPMRRLASISQLGMVALVYPGATHS
RFEHSLGVYLNSLRLLARFTGDASLNPPLDARSADAFVLAALLHDVGHWPYCHPIEDMRL
TGFREHESRVSEWIDQSELRQCIEQDWSCEIQDVVDLLEPAKKSAASQTSPIPLAFLRSC
LSGPIDIDKLDYLQRDSLHSGVPYGRNFDVGRLIESMCVHPNKGILAIGEKGRTAAEMMV
FARYVMFSEVYWHHTVRSATAMLQRAVFLMKDKIELESTFKLNDAQWVTRLVETSNALRG
TSLGNPHPLVDGLFGAQRRLYKRVAEFNAIDAVEGQSVEVHRQIARRPYWWLVAASEKLA
TRVSSMTGETVVAEDILIDAPPVKLEVDINVDVILRDGSFDPSASDADVNVDVSGNADAR
VTEKQSRPPLGVTLANVSPVARALARQQFDDQVKRVRVFVHPDKRDMMSRAVRAHGDWSQ
LLIDVVQSVDNEIV
>A0A379D6L7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pluralibacter gergoviae|TrEMBL
MLLAQISDTHFRSAGEKLYGFIDVNAANADAVSQLNALRERPDAVVVSGDIVNCGRPQEY
QVARRVLGGLNYPLLLIPGNHDDKAHFLEALSPLCPQLGRDAQNMRYAIDDFATRLLFID
SSLAGESKGFLTPQTLEWLEAELVRADGRPTAIFMHHPPLPLGHAQMDPIACENGHLLLA
LADRFPALVRVFCGHNHGLAFTQYRQLTIATVPGTVHQVPYCHEDRRPYYDMSPPACVMH
RQVGDQWVSYQHSLAHYAGPWLYDAAISCPLEDRPC
>A0A377Z5A0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae subsp. ozaenae|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFLGD
RWQILLLDSQVFGVPHGELSDFQLEWIEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSL
RNAGRAGQRVERLAAGEASFVRPYSSGTGSRLEWPAHDGDAVDLASSLNRTGANFTLDTV
SPGWRWLELHPDGTLTTEVCRLGRRRVSSGYCFRRLLMATLLYLHGFNSSPRSAKATALK
TWLAQHYPEITMVVPELPPYPAETAELLESIVLEHGGEPLGVVGSSLGGYYATWLSQCFM
LPAVVVNPAVRPFELLNNFLGHNENPYTGQQYVLESRHIYDLKVMQIDPLEAPDLLWLLQ
QTGDEVLDYRQAVHYYASCRQTVEEGGNHAFVGFDDHFTQIIEFLGLR
>A0A376MJU7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli|TrEMBL
MLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSA
LQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLH
HHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC
VQFKPHCSQLYAGYHRARLAYSRVTC
>A0A484YT63|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLGVAGT
>A0A7X0CJ14|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mucilaginibacter sp. X5P1|TrEMBL
MLRTHRFITVLYFLLIPFSVFSQSAPSFRIVPLGVLGGIDESNLSAYMIAATGTNNYVCM
DAGTLHYGIQQTVDNKVFSIPTEQVLRQYIKGYCISHAHLDHIAGLIINSPDDTAKNIYG
LASTLQTIKTHYFTWDSWANFADDGEAPALKKYHYQILTPDSIIPIKNTGMTVQAFPLSH
SNLTSTAFLVNSNDVYILYLGDTGADDIEKSHNLHKLWQAVAPLVKSKKLKAIMIETSFP
DEQPDKTLFGHLTPHWLMAEMDDLAALTGTDALKGFNVIITHLKPPQTSIYKIKLQLFNE
NKLNLNLIYPQQGEAIDL
>A0A177H8E4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodobacteraceae bacterium SB2|TrEMBL
MKLIHISDIHLTAPGERMGGLNPHRRFAQALDDVRAQHSDATRIIITGDLTHWGEPAAYA
SLADALTDVPCPVRLLIGNHDDRIAFLSVFPDHPKDHSGFINYAETLDTTRFIYLDTNAW
RTHAGHLCEARRDWLENELKDCTRARLFMHHNAMPLGLPAEDKIALVPEDRAPLAELLST
YRDRVEYIHFGHIHAPVHGTWCGIPFASVNSTGNQSLPDLTDQELLHSAPMAPSYAVILT
SDGGTIIHDIPFTWDGPVFSAGTAWEDWAKPVAIE
>A0A177HA29|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodobacteraceae bacterium SB2|TrEMBL
MLIAHISDFHIFADNPESMLVRKDAADVARKVIADIKDHIPALDVVIFTGDLADGGSPED
YDLLKEILSPLSIPVFVMPGNHDNRENMYRAFKATTPFEPSPNLNYEAVVNELRILALDT
LVDGAIHGALNSDQLDWLQRKLQDQHSGPTIIAMHHPPFPSGVTAYDKIGLKAGKERLGK
IIAEYKTQLIILAGHIHRPFQALWHGAFCQVSGGSAFQHGLDLRAHSIDPGGVSEPYSYH
ILSFKGSEKFINHVRYVRL
>A0A139Y4N8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii ARI|TrEMBL
VLFIMRLVRLYRLHRPPTGSLAIGKKEVFTSRVERIIAVLNKALEIEELTTREKDSLKWL
IQTISSGKLYEMGSEEKKKTDSHVQAWISIISTQSQSANQMADDMENILLERVKQMTKAG
DAETDMPAVLQLEYGIDVSLDHAIEGYLANNLITWNFDVFRFHVIAGRAALPKLFVRCLQ
HQEVCSLFNLKIENMLRFAMELEKTSFSTTPFHNSIRSAEVLQAMHLFLAFFDTQIKGFF
NSREILAALLAAVVWDYQHPGFSSAFLIKTQHAIAIRYNDRNVLEHHHVAAAFSLMQKLG
ENDPLLAFPEDQYIALRKIIIQLSQSGSRSNQTACLSLLKTKLQQAEFPRSITEDKNIIL
CNLMNAANYSFLGRPLQLYLQWSQKYMEELFMQGDRELELDMPITKNCDRHTTSEAVVQL
GLIDGWAIPIYTTLAQTVPKLNAIVVSHLRRNRLHWLDEQQEEDKSKEKQTKVTPIKRYS
KTKQGSTEATGNGELSKPEATTVEIADGTAGVPELRASANPLSEVD
>A0A483AI10|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|bacterium endosymbiont of Bathymodiolus sp. 5 South|TrEMBL
MKHFIQISDCHIDDNAQTMGINSHENLIKVVDKIVTLQSDALLISGDLTHNGTPYSYKKL
KEILSPIETDIFVIAGNHDDSDNLASEFGACLFDRIALDAWDIINIDSVQIGKISGFVTT
NALTALDQQLQHSNAKYNLIVLHHPVVAMNSEWDDALSLENPQDLFAVLDKYPKVQAVLF
GHAHESVEFDKNGLKIIACPSTATQFNDEQRIGFNYYTLFDDGRLDYETQWINS
>A0A378QY22|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moraxella caprae|TrEMBL
MTYPTHLSAPSDFIIAQISDLHLSTHIPTNTDKFLKVLDFALTFKPNLLLLTGDLVNDGH
LPLYDWLFDTLDKTNTPYLCLAGNHDVTHEMGHDLPFDKRTFFPIAKDDRLIDTHRLVID
LPHATWQLLAVNSALHGHIYGRLDDGQLAFLKTHLVHAMPALIALHHHPTPVGSAWIDEH
MLQNGNEFWAILNAHTTNTTNRPHVLCGHVHQAHILQQNGGTLYTCPATSRQFAPHRDEF
GIDDVASGFRLLQLHNNRTLDTWVKRLDNSGF
>A0A1B1NDK6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serinicoccus hydrothermalis|TrEMBL
MSQPAPQFGQHPAPLRTIAHVSDTHLLADGALQLGAIDTTARLRTALERLTRLDPAPEAI
VITGDLADLGEPAAYRQLRELVDPLAADLGAQVVWVMGNHDERPAYAAELFGREVGVDEP
QDAVYDVGGLRIISLDTTVPGYHHGELRDEQLRWLAEVLSTPAEHGTILALHHPPIPVPL
VPAAAIIELLDQDRLAGVLAGTDVISILGGHFHFSSHSTFAGIPVSVAAATCYLEDPAPD
ARFTSAVDAHQSVNVVHVYADRVVHSIVPVAPAPEVAGHPAEVAAQLAQMSPEQRRELVS
RKDSALGSG
>J9E4I4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Wuchereria bancrofti|TrEMBL
YFVKLFATYFQKRGLLKTFEIPSSILLNYLLHLEHHYRDNPYHNQVHAADVTQSVNVLIS
SPALQDVFSELEVLASIFAGAIHDVDHPGFTNHYLINTSNFFFYFFILK
>A0A1S8TK09|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium sp. BL-8|TrEMBL
MRFIVFSDSKGKKNGINEKVLKTLMHESCELRPAPEFIVMCGDTVAGSSKEEILNFQLTK
LRRIIEQYHPNKPLFPVIGNHEVNIEPLNDRFEKIFSQVYNDLTPNEYLYAYNKTVYYID
IADMRFIILNAFHPGLTHRIGKDQIAWFEEKASEFKRNKFVFVHSPAFPTGAHLGHCLDL
YPECRDEFWKIVDKYNIDIVFSGHEHNYSRKVIDASFSNENFCYENSITQVITGGGGEKL
RDKYTSKKGVVIPPIAVYHFLVVDVETNYINVSAISSKGSKIDEFKIDKNENRINSHSNS
IFK
>A0A1S8TQF8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium sp. BL-8|TrEMBL
MNNDFKRQHLKVKAGTTIFASTGILGKNSPNRMSTEFFYKAFKGNKIILLNSDYYFNVAT
YSLNFDDKYIYTYCYQEEECWTTYNHDLSGDSYRQEDYIFTEEVYFRICLKRVDCKDFTD
EEAQEINNILLFLSKDSTEGYKEKSYFSNELQKTVDTILEKRTKKSLVLCVLSDSHVTIN
GTWKYTIHNIKSINRKVSFNGIVHLGDLTDGMVSADVTRKYAQKIINDLREINVPLYIAI
GNHDTNYFNGNLESFSEKEQYEIYQKHSEKYVNRDFQKLYYFSDFNDVSLRCIFLTSFDH
NEKLRYGFPDEELIWLKKVLDTTPTGYSIIVFSHEAPLSILDYWTDEIRNGDKLMSILEE
YHLCENRKIMAFIHGHTHADYIYTQKVFPIVSIGCSKCEYFTDKKPEGAITHKRKLNTVS
QELWDTLIITPSENKIDFVRFGAGVDRTL
>A0A1S9ZZY7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moraxella bovis|TrEMBL
MTYPTHLSTPSDFIIAQISDLHLSTHVPTNTDKFLKVLDFALTFKPNLLLLTGDLVNEGH
LPLYDWLFAALDKTNTPYLCLAGNHDVTHEIGHDLPFDKRTFLPIAEDDRLIDTHRLIIE
LPHATWQLLVVNSAVGGHVYGRLDDGQLAFLKTHLNHAMPTLIALHHHPTPVGSAWIDEH
MLQNGNEFWAILNAHTTNTTNRPHVLCGHVHQAHILQENGGTLYTCPATFRQFAPHRDEF
GIDDVASGFRLLQLYNNRTLDTWVKRLDNSGF
>Q4JN56|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured bacterium BAC13K9BAC|TrEMBL
MEMIQITDLHITKDIENIKNDCKPYQTLSTTLKHIEHHHSNVKDVVITGDLSNDYTRESY
MIIRNLLKKYQSTFYILPGNHDKLEHINTICDEQITTNSIDLSMSKTLVYNFDTHVPGKT
NGHLKKKQINELNKKLCINKEVDKVIIFTHHPIIKIGSEWIDEHISENSEELIQLMLSHT
DKEFKIFSGHVHQEFNCIKNNIEFFTTPSTCYQFKNQSEIFALETNLSYGYRVITLHDNS
IRTKVLRI
>A0A7S4H0M7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serratia sp. Tan611|TrEMBL
MLKKILAVCLSGYSALALAGFDVVALGVDGGVSDGNLTSYLIRSDSQTQYVALDAGSLLP
GIGKGLEKGSFPQVTPEAAAPYTPQGHIFRRLIGAYFISHAHLDHLAGLIIASPEDGKKT
VYASNDTVLTLRNHYFNWKSWPNFSDSGNGQRLGTYRLQPVREQQRFTFGTTGLSGVMYP
LSHAGYHSSMVLLADRTGAFAYFGDTGPDALEQSRQLDSVWRALGPLVANKKLKGMIIET
SYPNEVSDSKLYGHLTPAWLLKELKNLQKYSGGDGSLAGLPIVISHIKPSLQQGEDRRAM
IQQQLEQANDLGVKFIFMAQGDRQQF
>A0A482YW93|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bathymodiolus heckerae thiotrophic gill symbiont|TrEMBL
MIKLIQISDCHINDQAVVMGVDTQANLKKIVKKLDDCKFEALLISGDLTHNGTANSYTYL
KEILSPIEVPIHVITGNHDNVVKLNIAFKDNLFSCVEFGNWEMISINSVQPEKTSGLVTS
KALAELDQRFLNSNADHILVVLHHPIVAMNSSWDDSLSLENPQDLFQVLDKHSKIRCVVF
GHAHESADFYHQNCLIVSCPSTALQFNQESRIGFNEFTLHDDGQINWTTQWI
>A0A132C326|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Tritonibacter horizontis|TrEMBL
MPGFIQITDAHIVSPGALAYSRSDTAEALRRAVETINAKLPHWGGIDCAIVTGDLTDHGT
PEEYAHFLSIMDELALPWLAIPGNHDQRDPMRKALAGASWLPDAGPLHWVRDFGPFSVIG
LDTLLEGAHHGMLCDAGMAFLDTTLSAIGDQPAIVATHHPYIHTGIPAMDADNLRNGAGV
IARLEAHPGPVRMVSGHVHRAVAGQLGRVTCQISPATCHAVLTDHRAGLDPHLVLEPGAV
TLHRWVEQPGAGLVSDVIPTGIFPGPWPFED
>A0A7R8D973|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lepeophtheirus salmonis|TrEMBL
MFSEALLQGGNGVGLLKLGLVKGLVAGALLSNIGGRQGGFGGGRRGGGRNNRRHGGRFGG
GRLGGGGFGGGGFGGGGFGGGGFGGGGLGVGGFGGGGFGNGGFGGVLLRRKRAINEYEEI
LLSASQEDQNDCAKRLVCEISSLPPTTMSLEEVQIASAFNSNYLDISKATVEFELAAQIG
KTCWTGAMLSCL
>A0A517PW50|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia chilikensis|TrEMBL
MPVHLPAQNRRQFLLTLGAGFLTYSAGAFAKDSQQSDIIYLLNDTHIGEKHPENSPVPSH
LRKVVSELVSLEQKPACVLINGDLALRDGQPGDYRHLAKLIRPLQEAKIDMHLTLGNHDE
RDVFYSVMQEEQPETPPVKSKHISVVQTPHANFFLLDSLHKTMVTQGTLGADQRTWLAKA
LDAHADKPAIIMTHHNPRLGGDPNHFPGGLTDSVELWEILAPRKQVKAYIHGHIHHRSNA
EHKGIHIINTPATSYVGNPKASTTGWTIAKLSPTGITLTTRTTDDQHPWNHQSQTLTWR
>A0A1S8LJF1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium roseum|TrEMBL
MNKKRGLLSFLITTITALSVFSVAAVKANAQYEFDVISDTHIGSDDMGGWHATRNLKTTL
NCIAKYHSNDQCVVFNGDNVDTAYQDSYDQLYNTIAQVKNDLSSQGKTIPYMYFNIGNHE
YCFGGTNTGNYQTCLNNFNYNTNRIRSMIGSRAGVTDTNRANSYDLQYINNKNDRLAFLG
TDELPSNPCDAYLAPSQIDWLNSTIIKNKNEWTTSSRGKKPMFVFLHQPLQNTVYGSDPT
NPNFADWGTLLNTDTLKQYALRTNHPEVIMFTGHTHRDFDGSYYGDSENFCTLTPSYSSV
FGVPSIGNTDGDPEGYHVTVYSDGVVVQGVKYTSSGTVQVNTRTINF
>A0A0H2M6R6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Variovorax paradoxus|TrEMBL
MLIAQLSDPHIRAEGELYQGVVDSNRMFAEALAHVHALDRRPDLLVLTGDLVDEGRAEEY
EMARTLLAASRIPFLVIPGNHDRRESFRAAFSDHAYLPKAGPLHWCVDDHAVRIIGLDSC
PAGKHHGHIDAEGLAWLARVLAKDTVKPTLLMLHHPPFTSGIPYMDAYRCMEAQQLEDVV
RGAPNVELVLCGHVHRTMLRRWGGTVVCSCPSTTTEIALQLRPDAPPQSHVGPRGCMLHL
WDERHGMVSHVSHIGDFAGPYAFA
>A0A0H2LTW5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Variovorax paradoxus|TrEMBL
MSCLLQISDTHFGTEQPEVMAALERLAQALSPQVVVLSGDITQRATRAQFAAARAFVGRL
AAPAVLAIPGNHDIPLFQLGARLFAPYERYAGAFGTDLEPVFESAEWLVVAVNTTRWYRH
ADGEVSPAQIERVAARLAAASASQLRVVVTHQPVMVTRQEDMSNRLHGREAAVARWCAAG
ADLILGGHIHLPFVRSLHDAYAGCPRTAWAVQAGTAVSSRVRAGHPNSVNVLRLGTPEGV
RACQAERWDHSAADKAFVCAKVLRLPLASAAAPA
>A0A212JVB5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Alphaproteobacteria bacterium|TrEMBL
MILAQLTDSHLKAGGRPAYGRVDTAACLRRAVAAINAFAPAVDAVIFSGDLTDAGSAEEF
AAVAGVLADLRPPVFAVPGNHDRRDTLRAAFAATGFHDPAVEFCAGVAEGFLLRLIGLDS
SVPGAPHGEIGAVQLDWLAARLAERPEAPTLVFVHHPPLNVGIRHMDVQNLRDGRRLLEL
LARHPQVLHLACGHVHRAISATVGGVAVSVAPSPAHAVDLDLDPAAPPGFRLEPPMLRLF
RFVDGVLVSHLGVMDAAPGPFPFFDARGGLID
>A0A2G9V6D7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Teladorsagia circumcincta|TrEMBL
MQTKRSVRILYELAQCCAQIANTDLCELYIQDEEGVYLVLKETGEQPQIKCRKVKRPRRN
PMHMIKLVDVNETNIGEIHFNSPVSERDKQIINVICTWAGGSLHYAQNFAAKLVEADRAS
LFLVDSKNHELYARIFDVGKDGEELEKINKEGHKEIRVIGVVQMVNKREGVFTKSDEDSF
EMFAVYCGLALHHAKLYDKIRRSEQALALYVSCLCHDLDHRGKNNAYMKSMMTPLASIYT
TSVMEHHHFNQTVTILQQDGHNILKSMTSSEYKQALSLIKHCILATDLALFFSNKAELNK
IVDSGKYDVREDHHRRLTQAILMTGCDLIASAKPWYIQTETVKVIFEEFYEQVGFMRGIC
LPCYDLIAKVIPESAFLRDQCEYNAKKWEELAAEQAELNKQKSEEGQPTAEEENK
>A0A653P0G3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Flavobacterium sp. 9R|TrEMBL
MRKVFGWVLLFLVSTIVSFGQKAKPVFEVVPLGVYGGIDERNLSAYLVAPFGTKEYVCLD
AGTVHSGIEKAIEKGTFSVPSSTVLRQYIKGYCISHAHLDHVSGLIINSPADSTKTVYAI
APAMKMMQNHYFNDQTWANFGDEGLGKPLKKYHFETLSFGKTIPISNTSMTVQAFPLSHV
NPYESTAFLIKKDNNAVLYLGDTGPDSVEKTTNLADLWKAIAPLIQKQELKGIFIEVSFP
NEQPDAFLFGHLTPKHLMKEMQVLAALTGKEALQKCKIIITHLKPPAASIQKIKQQLAAP
NDLGLTFVFPEQGVRMEL
>A0A016UJN3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ancylostoma ceylanicum|TrEMBL
MDKGGATEIQPFGVLVRRRIHAAHRDLTRIPNAIEAFTSYWKPESSPTTDGHSAHPQSSP
GTSSGNESPSLKKNAIRKESGSLCDTVVTTVDGQQFDTRELDGDRGMSMVADWSLPIFEI
AEKHRDTVLSRLTYTVFKQADLFRIFKLSPIKFFNFFHALERGYWDIPYHNRVHAADVLH
GCYYLTCHPVRPLIGPTTSPDSLLPPPLTPAAPISSSMSTLELMALYTAAAMHDYDHPGR
TNAFLVAAEDKKAILYNDRSVLENHHAAESWRLLQLTENNFIETLDPAETKRFRYLVLEY
ILATDLKQHFEIIMMFNEKSSEMELLNESDRLLMAKMIIKMADINSPTKPYGLHRQWTDR
ICQEFYEQASEKTNRCTYTSISTKL
>A0A1C6CNZ5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Clostridium sp|TrEMBL
MKFLHLSDIHFLREYPKAEKGYNAIFNDMTSPLIQLKKALIMVDLSKIDFVIITGDLVES
GMYEDYFSLKCELEKLLGNVPYILTLGNHDNKAAFYKGWFNKECNEPYNTVNEIDNLRII
SFDNSVYKNSDGFISNEQYKWLENQLKDSSKKDTILILHHHLIKDQFTTPSVDIDDNFEK
IIRESSLVGIFVGHTHHPFNGSFADKPYFSTGSLSFIGHDEGNGIVRFEENAQFSICTYE
DGKISVEVLSASNDNKLLGIVNFKE
>A0A8B4HZT7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas fluorescens|TrEMBL
MPSVSALNPDAPLLLVQLSDSHLFAEAEGTLLGMNTCESLRRVIELVREQQPQIDLVLAT
GDLSQDGTLESYQQFRDLTRPIAAPARWIPGNHDEPQVMAHAAVHSDLLEPVLDIGNWRV
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPSRHHLVCFHHHPVPIGCAWMEPIGLRNPD
ALFAVLDRFPQVKAVLWGHVHQEIDRERNGVRLLASPSTCIQFTPGSEDFQVSEQAPGYR
WLRLHADGRLETGVERVKGFEFTVDYGSNGY
>A0A486XIU7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Rhabdochlamydia sp. T3358|TrEMBL
MIRCAHISDLHFAKPSWKINQFFSKRWIGNANFYLRRRSQFCFENIQALPLLFKQLGVSK
VLITGDLTTTSDEKEFLMAQAFIQRLEEQGLLVVLLPGNHDQYTKTAFARKTYYHFFPSC
FSESTCNLKDDGLTIVEIGNKWSAIVLDTAIATPPLACYGFFSEELEERLKQALKQIAEN
HSVLILNHFPLIYNETPEKGLKRSEALCDLIKEFPQVNLYLHGHTHRHCIADLRQSGLPI
ILDSGSIIEKKTGSWNLIELHEKEFWVEGFKIINRKWQPTSRSYFKVNNV
>A0A086QJL4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii VAND|TrEMBL
MHRLLDWDFHVLALPPASAVLVTRDLLTQFALKANMDIPGEILMAFSVAIYKNYRPNPYH
NFYHALNVTQVLCLLLALPDVAAQFSPIDYLVLSVAALGHDLGHPGANNLFMTRFDCWPS
RIYQNVSVLENYHAASLFQILRHPAFNVFCSVSPTNFAPIRKRIISAILWTDMAKHFDVV
AKLQAKIQGEMVLAEGIIVTLTKPYLEGLLLHAADISNPMMDFELCRDWAFRACDEFYQQ
NKMEEMGGFPPSMPSFEHFDEYNVAKCQVGFIDAICKPLFNSLALMFPAQLGDRATQLQK
NRCVPLIIFPT
>A0A0P1EFV0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ruegeria atlantica|TrEMBL
MAQFLQLSDLHVVEEGALASSVLDTRRTLTAVIDRLLEMKAALDPLDALLVSGDISDDGS
ADSYAFARAELERLDMPIYVVPGNHDAREPFRAAFANLDATPPSGLIDWATTIGDTLVVG
LDTLVEGQGGGRLREDSLDLLRNALDTAGQGPVVIMLHHPPIKTGIRFMDAIGLENAEAL
EAELADTRCDITLIAGHVHGIHHGRLGHHRVATAPSVCSGFALDLRASATVGFLTGPTGC
AFIDTAPGGIWSAVPLDPSDGPFPF
>A0A7L2KUC5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Zosterops hypoxanthus|TrEMBL
LVKQLETGEVNVEELKRNLEYAASLLEAVYIDETRQVLDTEDELREMGSDAAVPSEVRDW
LAPTFTQQARAKGRRAEEKPKFRSIVHAVQAGIFVERMFRRTYTAVGPSYSSSVLNCLKG
LDQWSFDVFSLHRAAEEHSLRTVVFELFTRHSLNSRFKIPGAFLTSLLEALESGYGKFRN
PYHNQVHAADVTQTVHCFLLRTGMLIHQPGTLPPRGHPSLRWWHSPSPWPLSPCPRVPRS
DTAILYNDRSVLENHHISAVFRLMQDEELNIFVNLTKDEFAELRALVIEMVLATDMSCHF
QQVKSMKTALQQLERLDKSKVLSLLLHAADISHPTKQWAVHSRWTKALMEEFFRQGDKEA
ELGLPFSPLCDRTSTLVAQSQIGESWGCPLSLCCPHTVPALSPACPLLSPGFIDFIVEPT
FSVLTDVAEKLVTPLAEDGSKGKGNPAGGQQPRWGW
>A0A1I7YYW5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Steinernema glaseri|TrEMBL
XNGPTRAQRSHSSPIDLLGGLPFPLVSRELTRHLQLHHPSRQRKRSVVDALREKPRGTAT
EPRRRVSADVKNALENESSWGFNVLELERVTDHHPLVHLGTKLFDRWKVAETLQCSSEVT
AKWLLMIEEHYLTGNPYHNATHAADVLQATSFFLERDRVARTVQDTHAVAALIAAAVHDL
DHPGRGNSYLINTRSPLALLYNDVSVLENHHVALAFQLTFEPKLQANIFERQPREEFNQM
RQAIVDMVLATDMSRHFEFLSKFQQTVFDDDCNDPDERGLNSMTVCRMLIKCADIANPTR
DWSLCQKWAVRIVEEYFSQTAEELEKGLPVTMGLFDRRACNVPATQSGFIKMFARETFTL
WCEFADCPRLLVHLEENFKNWERLSEHWDTSLNEKIAEVTFDAP
>A0A449DBV7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Brevibacterium casei|TrEMBL
MTDTCVLHLSDVHATVDGRLYDRVDGIARLDTVGDCVRESGIAPDVVVITGDLVERGHAA
AYPELARALLRLEERVEAPVLTVLGNHDDPAHARVLPGHASAHHRLVHLADLRILLLDSS
SGMLGRDQIAWVREAIAQPYGRGTLLALHHPPLASPLAGPAGLVDAPELLAAIAGSDVRA
ILAGHLHHPLTANLSGVSVSVGPSLAYHRVMNAGPGFVAGHDSPMLSLVHLLADTIAVTT
VDLHAPPSLFSTPVSAGPLTAPLTTPLTTSR
>A0A0B7J633|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Photobacterium kishitanii|TrEMBL
MFKKSLLVLLCSFSAYAQAGFDVITLGSKGGIQDGNLTAFLIKDTHDTNYVTLDAGTVVN
GLIVADEKQAFKDIKLPKDSPYTKVGYVLREKIKGYLISHAHLDHLAGMIITSPDDSRKY
IYGLPSVNGTITETYFNWQAWPNFGNRGQGYQLGKYQYRDLSAQKWLPIKDTYLHAKALP
LSHAGIESSAFLIKNNHKQVMVYLGDTGADSVEQSDHLNSLWSTLAPYIKNKQLKGIMIE
TSFTNKVPERSLYGHLTPKLLLEELAVLEYKAGGKGSLTGLPIVITHIKYSLLKNIDPQS
IIKQQLNAGNTFGVTFHFPVQGERFIL
>A0A484NU81|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|plant metagenome|TrEMBL
MLIAQISDLHIRLPGQKAYRVVETDAYLPPVVDALNRLDPRPDCVVITGDLTDFGRPAEY
AHLRKLLAPLQLPFFLLPGNHDDRQALADAFPEHAYLRTDGPFIQYAVDQHPVRILALDT
VVPFKGHGALCAERLQWLETELAREPGRPTLIAMHHPPFKTGIAHMDAIGLLSGAPELEA
LVRRHPNIERIICGHLHRTIYARFGGTVASCCPGTAHQIALDLRPAGPSAFVMEPPGYQL
HTWQGGALTTHSAVLGEFPGPYPFHEEGALIDE
>A0A8H2QHX6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Burkholderia pseudomallei|TrEMBL
MLLAHISDLHIKRPGALAYRRVDTAAHLARCVARLNALEPRPDAVLVTGDLTDFGDDDEY
AHLKALLAPLAMPYYLLVGNHDDRAALRRAFPARVELQSGEFVQYALDLGPLRVIALDSQ
IPGASGGTLCDARLAWLADQLDAARDRPVIVALHHPPFACGIGHMDAMRLAPDASSRLDA
LLRRHPNVERVLCGHVHRTMFARFGGTIASAVPAPAHQVTFDLRDGGPSSFSMEPPAFAV
HRHAPGAGLASHHVYVDASDGPHPFFEPTGTLID
>B7QM66|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ixodes scapularis|TrEMBL
MYYHGSNSRGTLDVENRVVLNVGGIRFETYKTTLKKIPATRLSRLTEALANYDPVLNEYF
FDRHPGVFAQILNYYRTGKLHYPTNVCGPLFEEELEFWGLDANQVEPCCWMTYTVYRDTQ
ATLAILDTLDIENEKPSDEELARKFGIEEDYFAGKLSCWQRLKPRIWLLFDEPYSSLAAK
IMAVISVFFICVSILSFCLKTHPNMRVPVIVNRTVTQRNTTAWTLDKTKTDAHDAFFYVE
SVCNAWFTFEITIRFVVSPRKLDFVRAPINIIDFIATMSFYSDMLLQHLAADLENADILD
FFSIIRILRLFKLTRHSRGLKILIHTFKASAKELFLLVFFLVLGIVIFASLVYYAERLQA
NPRNDFTSIPEGLWWAIVTMTTVGYGDMAPRTYVGMLVGALCALAGVLTIGLPVPVIVSN
FTMFYSHTQAREKLPKQRRRFVGEPNSGAGPAPAPAVPQTRRMNAIKHHHHSREFANKPG
T
>A0A8B4NCQ2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acinetobacter nosocomialis|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIQQILKQHPEADAIIHT
GDLAQAPTPITYKRYISFMQTLGLPFFHTLGNHDNVDYFPLHNENHQEPVVVGLGNWRII
MLNSAVKGKVDGHLSLEQLENLENLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFKNVKALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLNNDGTFETKVFRLENFETHINTDISGY
>A8HNV8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chlamydomonas reinhardtii|TrEMBL
MQSERLLDQVDSWEFDTWALQEATQGHALSVLGFYLMQRAGLVSRFRLKPIVLARLLRAI
ESGYVDNPYHSAIHAADVLQTMHVIIHAAQLHVHYLDALGLLASYYAAIVHDFAHPGLTG
DFLIASSDPLAIRYNDRSPLENHHCAASFGLLRRQELNALAPLSQSERNAFRKQVIELVL
ATDMKQHFSILSHFNTAPQPVDDTERLLSLQLALKCADIGHLGESLEVHKKWLSNLEEEF
FRQGDKERELGIPISPLFDRSKQGVSKSQVGFYDFVALPLVHALSSAFPGTQQLMRW
>A0A378PJ05|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moraxella ovis|TrEMBL
MHIRHHLDTFTIAQISDLHLSAHKPIYTDKFLAVLKLALEHKPDLLLLTGDLVNDGDTHL
YDWLFDELQKINIPFVCLAGNHDITHEIGHDLPFHERQFLPIQADARLVDTHRLVIELSD
ACWQILSVNSAVNGQIYGHLDDDKLHFLRSHLANDLPTIIAMHHHPLPVGSAWIDGHILQ
NHDDFWQALTPHPNTKAILCGHVHQAHELPIPTPYPATLYTCPATSRQFLPHYGDFKLDD
VPEGLRLIHIYNKEKLATLVKRVQN
>A0A1V4SZZ0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium thermobutyricum DSM 4928|TrEMBL
MALYAISDLHLSLNTDKPMDIFGENWTAHDQKIKENWLQKIKDEDTVLIAGDISWAMKWE
ESEADLKWIDSLPGNKIISKGNHDYWWASITKLNNLFKRTKFLQNNFYVYEDYAICGTRG
WTAPNEKYTEHDEKIYKRECIRLKLSLDAAKKEGYEKFIVMIHYPATNERFEDSEFTKIF
KEYGVEKVIYGHIHGYGLKNILNGERDGIEYIMTSSDYLEFDPIKIL
>A0A364N466|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Stemphylium lycopersici|TrEMBL
MSFGKLYSYSGNPRTTSLLAVAKENGLEIEFVDTEPAKGVSEDYLKLNKLGKVPTFEGAD
GFVLSECIAIAVYLASQNEKTSLLGKTKQDYATILRWMSFANTEVLSPLGGWFRPILGRD
PYNKKNVDESQKAALKAVHVIEEHLMTHTYLVGERLTLADIFATSILARGFQYFFDKQWR
DSNPNVTRWYETIYNQTSYSAVAPKFEFITEAMKNVAPKKEGAEKKKEQPKAAAKPKEVE
EEEEEAPKPKPKHPLESLPKPTFVLDDWKRKYSNEETREVALPWFWENANFEEYSIYKVD
YKYNDELTLTFMTANLIGGFFTRLEASRKYLFGACSVYGQSNDSVVTGAFIVRGQEAIPA
FDVAPDVESYEFTKLDPTKEEDREFVNDQWSWDKPLVVDGKTMEWADGLALGKELGIRSG
TPGSTGTRGSGGGPSEDNVTGFLVRSTATQWSKNSVIAVDAGSHLASITNILSKDFPLVS
DPDPPLPTPRHNGGNGNGNGHGTANHDESPSPVTANITLSDEESDAETPASEREMPVTIT
TLSKGAFAGLPFPHQSARANALHVVREHVSTYLITHPHLDHLSGFVINTAAFHNTSRPKR
LAALPFTVNAIKNHIFNNIIWPNLTDEDGGVGLVTFQRLAEGGNIALGEGSSRGYIEVCD
GLGVKGFKVSHGHCMQGPGHVHRGSNANLLETSGPPQPSNQIDGQDGRSMSFSIATQSAP
GTPGYTGNTDPGRRASGATVPQPQQSSQDHCVIDSTAYFIRTESTLTTPKREILIFGDVE
PDSLSLSPRTSQIWAEAAPKIAKGILTGIFIEVSYTNAQADAVLFGHIAPRHLLEELSVL
ADMVREKKKATEKEKEEIRMKKKRKRANGPLHLDGPTSSDQRKTKVNYLGVGKGIDSPIS
ATNPQTDDEMMSDVPTSRGGTGANTPNPLSAPQYSNSHNNSLGPHPSHPSAPAALNLATV
SAEHSRAMLAAAFDASPLKGVKVVIIHVKDTFADGPLVGGQIEKELREGESALREQGRGL
GCQFEVSKAGESYWF
>A0A1R4K8S2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mycetocola reblochoni REB411|TrEMBL
MSAVQLGQYPAPGQTIVHLSDPHLLAGGARLGGSIDCAAQLPTTLAQVERSGLDVSALVF
TGDLADLGEEEAYLALRAAVEPVADRLGATVHWVMGNHDERAPFRRHLLDDAGGDAPVDS
VALSGGLRLITLDSTVPGYHHGAVDDAQLEWLAGVLAEPAPEGSVLMMHHPPIPSPQPLF
QLLELERQDRLARVLAGSDVRVILAGHLHYASHASFAGIPVSVAAASCYTMNLAVPPERM
NGMDGGRSYTLVHVYADTTVHQVVPVGDFATWDTFDEAFIRRMEALDPSARREAFSRKRP
PASR
>A0A2G8Y750|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii COUG|TrEMBL
HPRFNLFCSIPPQAFSACRQRIISAILWTDMAKHFDMVAQLKAKIEDEMVLTEGIIITLQ
KPYLEGLLLHASDISNPLLSFDLSFDWAVRACDEFFQQNKLEEKLGQPPHMPTFAAFDLY
NVAKCQVNFI
>A0A5P2ZS44|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodobacteraceae bacterium|TrEMBL
MADPTFLHLTDLHFGAPDDPHLHSDTEATMAAILDRIAEIDPKPDFAIASGDLTNAGDAA
SYRKLARALEGIGMPVVYAIGNHDTRAGFREGMLGEAPGSDAPYDHDTVLAGVHVITLDS
TTPGAIGGALEPEQFDWLADRLADHADLPKLLVIHHPPMLGEEEEPDFWRGIRIADSLRL
GEMLQGRTDIKGILSGHIHHDRFSVWHGIPLIVGMGQHAATDILVTDRLRMVRGAGFGIG
RLRPSGLTMALVPLPSDRAELNTYPLSMLRDRAQQVENAAYAAQAERA
>A0A840RHT8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Silvimonas terrae|TrEMBL
MELQVLGCSGGIGAGNRTTALRLGKHILVDAGTGLGDLPLAELAQIDHVFLTHAHLDHIA
CLPLLLDTVAPVRTAPVTVHASQSVLDTLRRHVFNWQVWPDFTQIPQPDCGLLRYEVMER
GDVFTLDGLTLTALPVLHTVPAVAYQMDSGNASVVFSGDTDDHAPFWQAVNTIDNLQTLI
IETAFADHEATLARASRHLTPQRLVAALKVLPAGLDIRITHLKPFDHDLIMRELHDQTGG
SALIRRLESGDVIHF
>A0A173YBN6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium disporicum|TrEMBL
MKFLHLSDIHFLREYPKAEKGYNAIFNDMTSPLIQLKKALIMVDLSKIDFVIITGDLVES
GMYEDYFSLKCELEKLLGNVPYILTLGNHDNKAAFYKGWFNKECNEPYNTVNEIDNLRII
SFDNSVYKNSDGFISNEQYKWLENQLKDSSKKDTILILHHHLIKDQFTTPSVDIDDNFEK
IIRESSLVGIFVGHTHHPFNGSFADKPYFSTGSLSFIGHDEGNGIVRFEENAQFSICTYE
DGKISVEVISASNDNKLLGIVNFKE
>A0A8B6BWG2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mytilus galloprovincialis|TrEMBL
MSGDMEYDKSSHSLEITEEYGNMEIWLDAHPEFVHDYFARKAKKSMVDGWLLSHALAHSP
SLQLPGDNNSSGSNSRNNSGTNTPVRKISAQEFDRGDTLDPIISTIDGTPTFLGPSTSCQ
SLSSKCHRRSRSELKALDEKELMYELVIDICNDLDVTSLCHKILQNVCCLLNADRCSLFL
VHGRESEERYLAPKLFDVSADTTLQEVSENRGQSIKVPLGTGIIGNVAQTGEPLNIPDAY
KDPRFNNEIDMKMGYKTRSILSMPIKDCSGKVIGVAQAVNKISIQEEPFDEHDEKVFGSY
LAFCGIGLKNAQLYEKSLLENRRNQENNGVQYTLSQCCTKK
>A0A090F3H0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mesorhizobium sp. ORS 3359|TrEMBL
MKVIQVTDVHLGHLREIRYGANLNERLDRCIDHINQRHSDAALCIFTGDLTDDGEADSYT
DLRAALSRLAVPYRLLPGNHDRRANLIAAFPENGTDGNGFVQSFFDTPEGRLIFLDSLAE
GRVTGELCDDRLDWLDARLAEVAGKAAYIFLHHPPVELGLTLLDPLGLEQPQRLIDVLTR
HGNVRYIFFGHVHRDIAGTVAGIPFSVQRGLHARFMLDVVGDEMVEQAPPAYSIILIDGQ
RVVIHSHDFLEQWPLWSPATGERVR
>A0A5E5PMV9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Gammaproteobacteria bacterium|TrEMBL
MKHFIQISDCHIDDNAQTMEVDSHINLAKVVDKIVTLQSDALLISGDLTHNGTPHSYKKL
KEILTPIETDIFVIAGNHDDSNNLASEFGACLFDCITLGAWDIINIDSVQLGKTSGFVTK
NALTTLDKQLQHSNTKYNLIVLHHPIVPMNSAWDDALSLENPQDLFAVLDKHPKIQAVLF
GHAHESAEFDKNGLKIIACPSTATQFNDERRIGFNYYTLFDDGCLDYETQWINS
>A0A4W6DPW7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lates calcarifer|TrEMBL
VGWTEVRKEWRLLDTEDELSDLQAESVPSEVRDWLACTFSRKMGVAKRRPEEKPRFRSIV
HAVQAGIFVERMYRRTSNMAGLTYPPTALTALKEVDQWSFDVFSFHEATGDHALKFLVYD
LLTRYDLINRFRIPVQALVQFVEALENGYSKHRNPYHNLIHAADVTQTAHFLMLHTGLMH
WLSELEILAMVFAAAIHDFEHTGTTNNFHIHTRSEVAILYNDRSVLENHHVSAAYRLMAE
EDMNILVNLNKDDWRELRSLVIEMVMSTDMSCHFQQIKTMRNALTQTHGIDKVKVLSLML
HAADISHPAKAWPLHYRWTHSLMEEFFRQVLCCSGIHEAVFRALHTATQGLCCFLMSMS
>A0A086L0S1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii FOU|TrEMBL
KGVLLDLSLGPACGGVSRERRASCSAAVSSTSSRESDRREAIARDPDLTETERRDAERRG
MERKATDDRQKKARFLVVPQLVEHELLCHVGILWSLDLFKLDKECNGNALLHVGYQLLAP
LLAAGYLTCSREVVLDFLYSLQCLYIDTPYHNQLHAASVAHLAFSICHFLDLFAPLENAP
GDAAASQPVFAQYLSLAIAALGHDAGHPGRSNAFLVQTSSTLSVVYNDRSILENYHACLT
FYTLSHRKSNIFRGKTVTQYRDVRKKAIELILSTDMSLHFEFLTRVAARRENPDFNFVDR
EEDRALVLSLAIKVADLGHCALDWEAHTLWSARLKEEFLAQGDEELRLGLPVSPLCDRTQ
QGQLARSQANFIEFLFLPLAQHLAAVAPDDRFEATVVTRARQNISMWEGAQDEVDQASAK
>A0A086JL65|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii FOU|TrEMBL
PECNIFTHLPPEDFQIVRNRMIDLILATDMKMHFEMVSKFRLRRNSPDFCRTNDDDVWML
LRMCIKGGDLSHGLLSWDSHVSWSYRAASEFYEQGDLELAQGSFLRVFHFFVLLPPGRRQ
SRRRFALFSGAKVIQRDTTLPRSVSD
>A0A378WUA4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nocardia africana|TrEMBL
MNELTLVQLTDTHIRAAGEKLSDVVDTHQALIDALDKLRTGGRHLDALILSGDLTDNGSR
EAYLRLRDAVEPVAAELGAQVLYVMGNHDERAAFGEVLLGRTAGTVDVDTPHDRVMQVSG
LRIIGMDTTTPSRHDGRLEPEQLAWLSDHLRRPADRGTLLVLHHPPLPSAIPVAEFLKLQ
NAEELAAVVEGSDVRMILSGHNHMTAAAALAGIPVWVGPALAYRIDAMAPVGHQRGMVGS
GFTRLDVLDETVVATAVETTPSARIYDKSDTEVRDRLSAVATEAR
>A0A2Z3J573|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salinisphaera sp. LB1|TrEMBL
MPGDITLLHLTDPHLRARADARLHGWHVAAAFQRSLDAAMTAYPLADAIILGGDLVDDES
SAGYRWLDARLAALQRPVLAVAGNHDDPAAMRRHLKSAVVHDALGVGGWRLIGLDSHAPG
SDAGRIGPRALAGLDRALQADPAPTLICVHHPPLDVGSAWIDAIGLIDRDALRATLARHP
QVRGVVCGHVHQAGEYRLDGYPVWTTPSTMRQFRPGSPTFAEDSARAPGYRCLQLGADGK
ITTTVHRVPATRT
>A0A066PLR2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acidiphilium sp. JA12-A1|TrEMBL
MLIAHISDLHVRPVGRPANRVVETNMMAERVLRRVATLDPAPEAIVITGDLVDCGRDDEY
EELNRLLDRKLPCPVYVVPGNHDRREAFRAALGHLPGVTADPDFVQYSADIGPFRLIMLD
SVVPGAGHGELCPQRLAFLDAALEAAAGRKVLIGLHHPPVITGVAAMDSIMLRSSEALLA
RAAAHGNVAAILSGHHHRAIHAAHGGTMLLSVPAAAGHQSEITFDPKARAYFHLEPGGIF
LLRWTEPEGLTAMLDSVGDLPGPYPFVVEPEYPGMRRAGAAT
>A0A066PHJ0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acidiphilium sp. JA12-A1|TrEMBL
MSGGPGAPPLLVAQFSDLHLRAPGLTANRIVETNMLAARAFAAFAALAPAPDALAITGDL
ADRGEAEAYRLLAGLIERHVRVPVILIPGNHDDRAAMRATLGDRLAADDEAGVNRPAEHL
PVRLLPLDSTIGGESHGRLGDGQLRFLRDRLAADPRPAAILLHHPPIATGIAHMDAIGLE
NAAALEAAIAPHAARVAGLWCGHVHRMIHGRLAGAPVVIAPSVAHQVRFDLTPDGPSALV
LEPPAFVMHRWDGASFTSQMVFVDSYPGPFPFLS
>A0A0V0YA97|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Trichinella pseudospiralis|TrEMBL
MKPNPKIILYCRRHHRLAVAGPAITDPLASQQNFQLMDHSSQFYFLTLRKHACRLRYIIY
QMHRGEMSSKDLIDNLEYAASILESTYVDSCRLQVEEQIDQIDSEDVPEEVRKWLALTFT
QSVNEQHQKVSFKSVANAIRSGIRFDRLARRSMSSGLDIVPDNVAELLKNINDWNFDVFL
LNELSENNALKCVSMALFSKYNFLNKYKIPMVKFEAFLNKLQQGYSKHNNPYHNLVHAAD
VTQTAHWLLAQSGLVECLTDLELFAYLFAAMVHDFEHTGHTNNYHVQSSSDYALIYNDRS
VLENHHVSAIFRLMHDSSQYNILEKLTKEEIRQFRNLVIEIVLCTDMSTHFAQVKDVKQM
ITSDEE
>T1HS58|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodnius prolixus|TrEMBL
ALLYRRLADEDDELSEVQPDAVPPEVREWLASTFTRQLGTTRRRADEKPKFKSVAHAIRA
GIFVDRIYRRVTSTALLQFPAEVVKVLKTLDEWSFDVFALNESASCQPIKYLTYELLNRY
GILHKFKVVPSTLENFLGKIEEGYCRFKNPYHNNLHATDVAQTVHFMLCKIGLMNWLTDL
EIFSTLIAAIIHDFEHTGTTNNFHVMSGSDTALLYNDRAVLENHHISASFRLLKDDDCNI
LQNLSREEYREFRTLVIDMVLATDMSFHFQQLKNMKNLLSLAEPTVDKSKALSLVLHCCD
ISHPAKRWDLHHKWTTRLLEEFFRQGDKERDLGLPFSPLCDRNNIMIAES
>A0A0D8XEC5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Dictyocaulus viviparus|TrEMBL
MESRLNDWGPDVFKIDELSKNHALTTITYALFRERGLIKTFEIPSSVFVTYLLNLEHHYR
SNPYHNHIHAADVAQSMHVLLTSPVLTEVFSDLEVMAAIFAGAIHDVDHPGFTNQYLINS
NNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLCGLSKKQRLQFRKIVIDMVNILITFE
LVDSAAPEVIHHRRARLVLCNDERKYNGVVVLATDMSKHMSLLADLKTMVEAKKVLQSMI
HLADLSNPTKPIELYRQWNSRILEEYWRQGDREKELGIEVSPMCDRGNVTIEKSQVSTLI
RSQGSSNFLRYLVYINHSYH
>A0A0D8XID7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Dictyocaulus viviparus|TrEMBL
TFVGVAELCNKTGKTGFTRHDEQKARTFAVYCATSISHCLLYRKVQEAQRRSHMAAELLV
QGSQLLISQEDVNRLTSEPVKKWSMNKRKLASFLLRVPYHNWSHAFSVAHFCWISLQTPA
VLHGLDELERLALLIACLCHDIDHRGTTNAFQLQSKTPLAQLYSSEGSVLERHHYAQTVQ
ILLLPECNILDQLTRTQYQTVLSHIRDVILATDISAHLTKVHRIKAMVDQGYDSLSRDHH
YLFMCLLMTSSDLSDQSKDFRNSKAIAENIYKEFFSQGDLEKQMGASPMEMMDRDRAAVP
KIQLDFMDTVAIPVFEMVSKIMPEGRSTFEAISLNRQCWAALDEILAGRGNRPVLGLDYL
RDEELEKQVIERVQQRKKQSKVNCLR
>A0A385AQI3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Micromonospora sp. B006|TrEMBL
MLIAQLSDPHVTTGPLAAAPASGLHHALGAVLALRPRPDCVVITGDLTANGRPDEYLALR
EIVGAFPLPVHLATGNHDDRESLLDTFGGTPYLAGGFSAHYHVDLPDATLVVLDSLTPGS
AGGRLGDEQLAWLDGVLAGRTDAPAVVCLHHPPVAVGVPGMDAMGLADADALAAVVSRHP
HVVRVAAGHLHRPVTSAFAGTVLTTAPSTWIQVSLTMTDEEEPGFVAEPTAFLLHVIADG
GCVTHTVQVSHAAGRTCWF
>A0A2K4VNN0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas syringae pv. avii|TrEMBL
MPSAALSSSVLLVQISDSHLFAEADGALLGMTTRDSLEKVVDQVLAEQPHIDLVVASGDI
SQDGSVESYEAFRRISGRIDAPARWFAGNHDELPQMEHVAQGEVLLDPVVDIGRWRVTLL
DSAVPGSVPGFLADGQLQLLERSLSEAPDRHHLVCLHHHPVAIGCEWMAPIGLRNADALF
AVLDQFVQVKAVLWGHVHQEFDQVRNGVRLLASPSTCIQFAPGSVDFKVDTLAPGYRWLR
LHDDGRLETGVSRVVGMVFEADYGGTGY
>A0A2X2T4V6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cedecea neteri|TrEMBL
MESLLTLPVADGGRIRILQITDTHLFAGKNETLLGINTWKSYQAVLTAILAEQRTCDLLV
ATGDLAQDHSVEAYQHFAEGISRISAPCVWLPGNHDFQPAMFNALQDAGISPAKRVYIGD
HWQILLLDSQVFWCSPR
>A0A239RTN7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acinetobacter johnsonii|TrEMBL
MTLNNEKNWTIIQISDTHLMDQDHLEFVRMNPEQSFHHVIQHIVERHPQLNAIVHTGDLA
QVPVPRTYQRYLDFMQSLKTPFYQVPGNHDNAEHFPFHQQQNKVHVIHFGPWSVVLLNSA
VKGKIDGWVDEAQLNQLEQILQEFAQQHIVIACHHHPFEMQSKWIDQHKLKNTQDLTAVL
AKYHNVKIVLSGHVHQESWREWHGIQFYSTPSTSVQFKPLSDHFALDEQAPGYRILQLNA
DGSHETHVERVLHAQQKINVEISGY
>D4YR74|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactobacillus amylolyticus DSM 11664|TrEMBL
MITNDLNTEIWVISDTHLIADVLHDNGQAFSRMQKTSQGKDLYYQETVLKSFVKMANEKQ
PAAIVVTGDITFNGERTSAERFAQIFKGLTKTKLLVVPGNHDIFDGWAREFRGKKQFYAG
QISPMFWKSIFDKSYRASEDEDSNSLAYSVQLNPNYLLVLADSNYYGKEETTTAPFTKGA
INRDELKWLEKQFKKASQQHLRPILFMHHNLYAHNPVVNQNYVLDNAAEVRRLCARYNVK
LAFSGHIHAQNILGPQEMTPTTEVVTSSFCSTDQGYGVVRLHQKHITYVRKSFDMRKYLD
DHESQNYTLMHFHDYLKNLQLGTLAANLMQTDLKKNRDSLDLIRKMGRLFAEMNYNFYTG
QNHLKNNQLAKIHASEAYKTLINEHPEYELYLKTLYDTSSHSNLQVKIRY
>B8C496|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thalassiosira pseudonana|TrEMBL
KSLASWDFNVVELAKLCNGNPLLFVGWAPECQDGYDFVSNYEVKIPTLCSFLRVTESDYI
ANAYHNNTHAADVLQTLNTILQLGGDEFAHSSLDIFSLLVAATIHDVKHPGLNNNFQVNS
RSELAVQYNDVSVLENYSLTWFYQKLLGPERDSSIDIFSGLNKQQFSVSRSIIIKAVLDT
DMTHHFSMMKRISSHKETLEGKSRRDWLTPYTSRGCSYSPSMDMLTFLLHLSDISNPAKP
LFEYWTDRILEECYAQGDKEASLSLPISPLCDRATTSKKQCQIGFIKFVVKPAYDILGEI
IPAFGAVVSPHIQKSELFWEEYEDDVGVAKEE
>S8F358|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii (strain ATCC 50611 / Me49)|TrEMBL
MWFYSYLRHPNDVPSLCTHIRSSNIFLRLGPQYYLPEDERKSLFVRTCHLLYYLASLLFL
TTLTTYTAIKIPSSPSTTTELLSQLFPFNSIDDCNERLSCKVDCVLYAFPDLNCAKDDGS
LLTFGGNSYSSLYFYHYPGKDVPLQKEARTAWERCYQIMRETTGRLQFLQQDRETVERTH
TCFAGCKTNGAVTFTQKLTDGTPVVFDSGTDWLQMAPAGSLPQDTRPACNPSEPPSLLCV
EPTDECQHVTLRYQVCIGDTAFCFDIVRILITIALGVVWNVVLDAFVVWAMSIDDSDPQN
LGRVASKCGLQIIATAIIVSSFFCLVASMTRILSMDANIARHGTLWTSFVLVIIIDQLFS
FLFSVLIWYAMLRRCGRQLPDESRFQYKIHPSPVLVKLKKATRKIVNYNGFEMFFTMLLG
WMVVDLTCRMILCQFFFDETAFLNQADRILEVVDFIILILFIVEICLRIAADGLKIYFSD
PINCIDFFLVFFGFGIRIVDFFIQINKGIGNVLFIMRLVRLYRLHRPPTGSLAIGKKEVF
TSRVERIIAVLNKALEIEELTTREKDSLKWLIQTISSGKLYEMGSEEKKKTDSHVQAWIS
IISTQSQSANQMADDMENILLERVKQMTKAGDAETDMPAVLQLEYGIDVSLDHAIEGYLA
NNLITWNFDVFRFHVIAGRAALPKLFVRCLQHQEVCSLFNLKIENMLRFAMELEKTSFST
TPFHNSIRSAEVLQAMHLFLAFFDTQIKGFFNSREILAALLAAVVWDYQHPGFSSAFLIK
TQHAIAIRYNDRNVLEHHHVAAAFSLMQKLGENDPLLAFPEDQYIALRKIIIQLSQSGSR
SNQTACLSLLKTKLQQAEFPRSITEDKNIILCNLMNAANYSFLGRPLQLYLQWSQKYMEE
LFMQGDRELELDMPITKNCDRHTTSEAVVQLGLIDGWAIPIYITLAQTVPKLNAIVVSHL
RRNRLHWLDEQQEEDKSKEKQTKVTPIKRYSKTKQGSTEATGNGELSKPEATTVEIADGT
AGVPELRASANPLSEVD
>A0A2H6J0X3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|bacterium BMS3Bbin10|TrEMBL
MIIAQISDTHIALDTPDADRRLRDFAQTIADINALEPQPDVIVHTGDIVHNGRREEYMRA
REILGKARAPVFVLAGNKDDRENLHEAFAERGYLAPNPEFIDYAVEDFPVRLIALDTLSA
RGNKGDFCEARAQRLIGLIEAEPARPIAVFTHHPPFEVTQSREPHQFETRDMAVRLRRAL
QHSDRVRAVFSGHVHRAALGNVKAIRAATMPSTATSLRKGDYPADMKTAPVYQLHRFDSG
GGFTSETRIVRSGLEKPIPHKRTPLQVQALSRP
>A0A840TXH5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhabdobacter roseus|TrEMBL
MVSMYKVPSAMRFLACLFILHLVPWALRAQGTFRVVPLGTKGGLDESNLSAYLLAPAGRS
DYLCLDAGTLYHGLQKAVERGTFSGPAHQVLREQVKGYLISHAHLDHLAGMISNAPDDAN
KAIYALPSCLEIIRDHYFNGQSWPNFGDSGQPPVLRKYRYVALAASEEMPVEGTAMFVRA
YPLSHGSGYESAAFLVRHNTHYVLYLGDTGPDDVEQSNRLAQLWAALAPLVRAGQLKGIF
IEASYPNEQPDRHLYGHLTPRWLLHEMAALAHLTTPELLRKVPIIITHMKPTEGNETRIR
EQLRQENTLGLTFLFPEQGVPIDLP
>A0A086L3R5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii p89|TrEMBL
ETKTFSLAFVLGDFVTISANAADPASRPLTSAEIFREAQEAAALRPPPGCCLPLVKVFVS
SRGDRSSQDGDEKVESRQHPLPDDVTKLSVPVRTDALIQILARALDSVEGCKSADDSSQE
ESEIEPEVPFMPGELVYASPRSEGGKLAAGPGRKSLLVSCERSEANEASGKGGDSSPQKK
KRNTFRISVARRRTLRASASPHSQRESSVTSEAARHRNLLSSVFRGKDSPPRRSSRDTND
KASLSDDSKDKDGSDDEPVELFPLHNETLQPLFPGGDQIPEPLLFDVNSVVQAVNQVGLS
RPAEQLAAAIAQTPFQKDLDASAKFIDALDSSLALLRYYQTLPGRDGSLQKRRRSRRMTD
LDPQGTDRTWRPESKRKDPLAMMQSLSALQVKVPAEPEVQAFFNLASSTLSVEDPISIHQ
VLNWDFHVLNLTPSTATRIA
>A0A086L3Q2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii p89|TrEMBL
MGHPGVSNEFLISMRSFTSILFNETAVLENYHTLLYMDLLKNSDLDILKMLQPEAVQRAR
QRIIAAILATDRALDMKLIDLLNDVKSKNEKVPVPAALLDPNVRDACLIHAADHALSLLN
FPLHRKWAEKMAIEMHFQNTMDEALKLPKSYCSLSRLTEASLAGSQVTMIDTHYLPFFSA
LAWYFPGDLDMRVAVMKANAAFWQHLRDEEMRKTVALNDNPEQEDWRSAKLQVISSKFVE
NREKMHQKAAEMMQAEATDVFFDPYPMIVDQSGNEGEEDSFAKGVMREKSGMGGYAIESR
RRSADSSRGAERRESDAEAHHSEATHAPKPDEKSQLDKNGQRQSNSSGLEQGSNAEVSCF
QRASLRARFVDADVTIPATKQPVLSETHASATNVTSRGEQGNEKGNLDSTEQTTKIGDEE
KEARTDEMVGDPEETREKHDPPTVSHFEDRSDHRQVDAPDSLPEAAPNVGSQNPNSAGTH
PDTRATSSVSVPSNVADEEVAERVPAPVPADQSLSRTLLQSDEASQRKNQTKSLSNAESV
DTEEMSAFVLDEVSGFFYDQQGYVYDQQGNLRGYLDASGAFQAYSESELQYYAETMARVQ
DQEQADYAYPEG
>A0A1C5ULX3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Bacteroides sp|TrEMBL
MRTYPTLPHCFRLHFRLIYGCLWALLLGGCDMIEYHPYDLDIDGETDVNRRHIEQIEKAT
RGKDEIRFAVISDTQRWYDETEDAVEALNRRGDLDFVVHTGDLSDFGLKLEFEKQRDILN
GLNVPYVCLLGNHDCLATGLDVYRKIFGTEDFAFTAGNVRFLCLNTNALEFDNSSAVPNI
QYIRNEIDNVPEGVEKTVVAMHAGPFSEQFNNNLAEYFEYYLRQMPDLQFCVYGHGHNIS
VDDFFDDGILYYECTCAKKRAYLLFTLNADGYAYEVVNF
>A0A3R7M7L8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Trypanosoma conorhini|TrEMBL
MSQKKNGLNRPALAQLSTALFGRTSGESDKDARASDEGCFGEALFGGHAPARSLLFGDAT
SPWRAEKFGLQDNNPANWAGIQTNLKREVPLLQDPAETFERMNKVMHQTLKYVKEVESID
FSSREVTDFNGKVMEDPRRVFLSVCASVLANFSFIGQMDVEKLLSFLSALFESYATDNAY
HNALHAADSVQMLFIILREKPAKLIFTDDEIIVAFLATLSLSFVHPGVSNAFLARIDHPL
VWVYGDITTQQSASLTAFLYHLNREENRFIDLFANSGTQPFSQFLRELLFETVLNTAPRL
RGSLLRGLEKLAAAKAVELNDVPLLLSAVIILADNALVLRPHAQFVALAGRMVTEWLREA
YEEEQRSMEPLVPNLRGQVSENGLGLVVDYCKAWLVPVITAVRALVPQDLYDNMVGNTEA
ATSMSEAAEFEGQLTPCNERWNDGSVPVIDIIRRVTMHATSLDRKASKRAILNAASSRGV
SSFLSPSSSLCSPPGEARAFPDPAERRANPHTSRCEHYFSFLRLYDTYEKEGRPASEFAA
QLVFLALQLNHEYIGSYTHKGVEVCSKKECEEIAKLIMEKEEAPTTAEVIASPLRDGQQT
DGFILRLMEMYAEREREKGRNETPASNPTTGVRRALNCSNPVYGGMYSGKKS
>A0A447TVC1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salmonella enterica I|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPFAGRVQLAGSAQL
A
>A0A2N7QVC9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Dyella sp. AD56|TrEMBL
MNDIEDREIDGRRQFLKCMAWAGAGTLWLMHGGVLRAQPLTAKGVASATDASFGFVQISD
SHIGFHKAPNMDVAGTLRESLAMINAQKVSPDFVLHTGDLTHLSRPEEFDTLAGIMQDAR
MGKVFYVPGEHDVIGDNGAEFFHRFGERQQSGGWYSFDHRGVHFVGLINVLNLKAGGLGS
LGADQLAWLKKDLAALSPDTPLVVFAHMPLWPLYPDWGWGTDDSNEAVSYLRRFGSVSVL
NGHIHQIQQKVEGSITFYTARSTAYPQPAPGTASAPGPMKDVAPGDLHRYLGIRDVRHVQ
GSHALAVTEEVMA
>A0A087E745|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bifidobacterium subtile|TrEMBL
MQCSLRNTADDDGSNKEGGDDHDITIIHISDTHIAAADDRGARPQRDYDSRATFDLLCQR
IADSGLRPDLIAVTGDICDAEHGERARQAYRHVGERLAAAGGRIGCPVAYSMGNHDERAA
FRDVLLMQPALPGNATLSSGAKLSDETASSGDATPPMHAVSPGIVNTSPRTDRTDRTDIA
DTAALRGLRSDSRRSRPMEIRPSHPDDGVDYSFRLPTRAGELRVIVLDSSMPGRNDGSLS
AQQLNWLARLLGDSAPAGSVLLMHHPPVRPYQFEARQWELDAASSANLAAVVRGSDIRAM
LCGHVHLASAATFAGVPVSIAGACSRNQDPFWSRATTHSWDANHSVNLVLLRSTGHGTES
LITPAPLAGGD
>A0A1S8PRT8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium beijerinckii|TrEMBL
MKNNLRFDTNGKFKIVQFTDIHEGPSRDKSINLMNKILDYEKPNMVILSGDIIDGKCQTA
EDVKKAINHIAEPMENRNVPWCIVFGNHDDEHNMMTKEEMMNLYMSFEHNLSQVGYKTFD
RIGNYNLIVESSKDKTPKFNIYMMDSGKYAPGIIGGYDWIKLTQIWWYKKTAIKLKKKYK
RLIPALMFFHIPLKKFKKAWKTGLVNGERLEDESCAKINLCLFNKIVKIGDVKGIFVGHD
HFNNYCAALDGVKLGYAGYTGYGGYGDDKIPRGARVFLINEENPADFKTWTRREFDTELK
K
>A0A021XDL7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Shinella sp. DD12|TrEMBL
MTKLIVFTDLHMVPEGSTIIGLDPYKRLLAGIEHVNRYHADADRVIFTGDLTHRADTQSY
ERLRDLLSLLVPPAAITIGNHDYRERFLESFSYVKPDENGFVQQAIDFDDCRVVLLDTLF
APPYDYPRSHAGYLCETRLTWLDNTLSGAGGRPVLLFMHHPPHKTGFTGMDAIRLSNEGA
FYEIVLKHGNVRHIFAGHVHRTIGGSHRGIPFSILKSPVHQQPMPFDAPNASLSVDEPAA
YGIVVVTEDGLQVHNEDYEIARRDSEIA
>A0A3B1BJ99|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MTKPNCNLVSTTIKELADLPSGSLKVLQLSDPHLFADQDGRLLGMRTLKSFIKVLNHATK
TLGQMDLVVVTGDLVHDATAIGYSRLGEHLATLGIPVYCLPGNHDDTALIASTFSDNPSG
SKISIQHNNWSIILLDSQLPGSESGHISSSQLAKLAANLQAHPNHHTMICLHHQAIPIGS
TWLDTMTVDNADDFFAIVDQHPQVKAISWGHVHQDFEAVRNGVKLFGTPSTCFQFTPKKE
TFGIDKIPPGCRWLALLPDGQITTGLVRIKKIPTSIDLSGSGY
>A0A1W1DSZ1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MGVDTHTNLVSVVKAVTKHNCDTLLITGDLTHNGTLNSYQVLQRMLMPIESKIVVMSGNH
DQIENLNQVFSEQLISKFSLGNWEIITIDSTQPSKTSGYVTKQALDQLDQDLQNSVAKYN
IVALHHPIVSMQSDWDDSLSLENADELFNVMNKYPKIKAVLWGHAHQASEFNNGDVVLIS
CPSTALQFDNETRIGFNHYRLHDDGKLEYNTQWI
>A0A378AND1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae subsp. pneumoniae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQICAMRWMTSPPACCLST
PVMPARQKAG
>K0H5E4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salmonella enterica subsp. enterica serovar Heidelberg|TrEMBL
MSDPVRITNPGAESLGYDSDGHEIMAVDIYVNPPRVDVFHGTPPAWSSFGNKTIWGGNEW
VDDSPTRSDIEKRDKEITAYKNTLSAQQKENENKRTEAGKRLSAAIAAREKDENTLKTLR
AGNADAADITRQEFRLLQAELREYGFRTEIAGYDALRLHTESRMLFADADSLRISPGEAR
SLIEQAEKRQKDAQNADKKAADMLAEYERRKGILDTRLSELEKNGGAALAVLDAQQARLL
GQQTRNDRAISEARNKLSSVTESLNTARNALTRAEQQLTQQKNTPDGKTIVSPEKFPGRS
STNHSIVVSGDPRFAGTIKITTSAVIDNRANLNYLLTHSGLDYKRNILNDRNPVVTEDVE
GDKKIYNAEVAEWDKLRQRLLDARNKITSAESAVNSARNNLSARTNEQKHANDALNALLK
EKENIRNQLAGINQKIAEEKRKQDELKATKDAINFTTEFLKSVSEKYGAKAEQLAREMAG
QAKGKKIRNVEEALKTYEKYRADINKKINAKDRAAIAAALESVKLSDISSNLNRFSRGLG
YAGKFTSLADWITEFGKAVRTENWRPLFVKTETIIAGNAATALVALVFSILTGSALGIIG
YGLLMAVTGALIDESLVEKANKFWGI
>H7FNT8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Flavobacterium frigoris (strain PS1)|TrEMBL
MNGIAQKVQKPSFQIVPLGVKGGIDEKNLSAYLLAPLNTTDFICLDAGTIHAGIEKAIEN
NVFKISSEAVLKKYIKGYLISHAHLDHVAGLIINSPADSSKTIYATHSCMEMIQKHYFNG
DTWANFGDEGNGYLIKKYHFQTLQPEEQTPIANTTMTVKAFPLSHVNPFESTAFLIKNEN
TYALYLGDTGADQIEKSNKLSLLWTEIAPLIKSKQLKGIFIEVSFHNEQADSQLFGHLTP
KYLMNELHSLSELTGKDALKGFKIIITHMKPPTENFAKIKAQLKKQNDLEVQFIFPEQGK
RFEL
>A0A1V6GJX9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Verrucomicrobia bacterium ADurb.Bin070|TrEMBL
MNTMPLRSRMLAAALAMLGAAAAQAADIPLDPNLVALFADLHATTTKNNPHQRAGLERCT
REVLALNPRPANVLLYGDLSFNHGDTNDYRLLRTLVKPLEEAGIRWHAAMGNHDRRAPFL
AAFPERAAAVPLVPERLVSLVETPHADFILLDTCLEGPVNGGLDDAQRAWLRTVLSGRVK
PVFVGAHHPLAETGLATLLAASPACKGYVFGHNHTWRQQATDGVQTLCLPSTGHWGDIGY
VLVRLSADEAAFTLKQHDCYTPRPAATPEQAKPEWAERVKRNDGSQWRVPLKGDESGFVP
LFNGRDLSGWVPCNVPADTFFVRDGMIVTSGEPIGTMRTEKMYENFIIDFEWRHMKAGGN
SGLFIWSDALPVAGSPFSRGIEVQVLDPGFNVKGKNEWYSTHGDIFAVNGARLTVAGRIS
PNGQRSFPAEERTRPSPEWNHYRVAAINGDISLSVNGKEVTIARAAEPRKGYLMLESEGS
ECHFRNIVIREMASQTSKEEQK
>A0A143GJ62|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas yamanorum|TrEMBL
MNRPFLVAQISDLHLKAGQRLTYGVVDTLGALRRAVDHLNATYPRPDIVVISGDLVDFGR
ADEYAVLHPELARLQMPCYLVPGNHDNRQHLLDAFGDHRYLPASADGPLDWVVDDYPVRL
IGLDSTIPDAHGGQLLDSQLQWLDQQLALQPHVPTLLILHHPPFISGIGHMDREPFVNAA
ALEKIIARHPQVERLLCGHLHRPMQRRFGGSVSCVCPGTSHQIVLDLQEAAPAHFNLEPA
GYLLHRWDEQQGLVSHNGVFGDYPGPYPFYDAHGLID
>C2EK36|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactobacillus ultunensis DSM 16047|TrEMBL
MITKNLNTEIWVISDTHLIADSLHDEGQAFSRMQKTSQGKDLYYQETALTAFMRMAQRKK
PAAIIVTGDVTFNGERVSAEKFAEIFKPLKDTKVLVLPGNHDIFDGWAREFRGKKQFYAG
EISPLFWRSIFDKSYRQATDEDESSLAYSVQLNPQYFLILADSNIYGKEETTEAPHTRGM
IGKEQLKWIEKQFRYAQEHDLRPILFMHHNLYAHNPAVNKGYVVDDAVDLRRLCARYNVK
LAFSGHIHAQNIMGPHDMTPTTEIATSSFCSNDQGYGVVRLHSRHITYVRRTFDMTRYLT
KEEKQNYTLEHFHKYLKDLQLGSISADMMQSELNKYHDDIDLVREMGKLFGWMNYHFFTG
QNHIKSSELNKIHSSRAYQILMKHHPEFRLYLETLYDTSNHSNLQVKIKY
>A0A5B7DUG4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Portunus trituberculatus|TrEMBL
MGGTDGDPSASTAPKKRHVGDEEDELSEVEPDAVPQEVREWLASTFTRQLNTSRRKTDEK
PRFRSVANAIRAGIFVERIYRRLSSATFLQLPPEVTRILKMPPATLETFLTQVENGYCKY
KNPYHNNVHAADVLQTMHYMLSQTGLMNWLNDVEILATLVAALIHDFEHTGTTNNFHVMS
GSETAILYNDRAVLENHHICAAFRYGNGTE
>A0A8H8XKV5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. OF001|TrEMBL
MHSSHTHCAGAPLVLVQLTDSHLFAEEDGHLLGMDTADSLGRVVDLVLAEQPRVDLVLAS
GDLSQDGSLESYQRFAALTAPIDAPARWVSGNHDEPLTLQLACAGTERLAVVTDLGHWRL
VVLDSSVPGSVPGQLDAAQLEQLDAALESAGERHVLLSFHHHPVAVGCSWLDPIGLRNPE
ALFAVTDRYPNLRCILWGHVHQEIDGQRNGVRLLASPSTCVQFAPGSEEFQVSSEAPGYR
WLRLHADGSIDTGVSRVSGIDFVIDYSIKGY
>A0A2N7RSK9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Janthinobacterium sp. AD80|TrEMBL
MRIAAISDIHGNLDALDAVLADIARRGVDVTVNLGDIVSGHLQPRATAARLMGLGLPTIR
GNHERQLLGDPARMGVSDAYARAQLLPEQLDWIAALPATLRLRHDVLLVHGTPASDLVYF
LDSVTPQGSRAATPMEVAERAGDADAALILCGHTHMPRQVRLADGRLIVNPGSVGLQAYD
DEHGYPHVMENGTPHARYAIVEQGADGAWTAQFHAVDYDWEQAAKLALANGRPDWIRPLR
AGRVGPPDSV
>A0A841LNL0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pedobacter sp. AK013|TrEMBL
MLKKIFSILLFLSLCAIHAWSQEINTAFKIIPLGVKGGDDESNLSSYMIAPKGSEKYVCL
DAGTINAGIQKAIDHQSLKGISEEIQRKQIKGYLISHAHLDHVAGLIINSPADTAKNIYG
LPSVLNILRDKYFTWDAWANFANEGEKPQLKKYTYFPLIEGNTYPLEGTEMKVKAFELSH
GNPYKSTAFLISRNDSYVLYLGDTGADEIEKSDKLAKLWQNIAPLINAGQLKAIFLEVSF
PNEQPDKQLFGHLTPKLFFSELSKLEALTNKKAFKKVSFIITHTKPPQKTAEMVKKQLIS
GKPKDLKLIFPEQGKYLTIN
>A0A4U5LND2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Steinernema carpocapsae|TrEMBL
MSDGDDVFTDIEILAAIMAGAMHDVDHPGFTNQYLINSNSELAIMYNDESVLEQHHLAVA
FKLLQESNCDFLSGFSKKQRQTFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVSGSHA
LELDKYNDRIQVLQSMIHLADLSNPTKPIELYRCWNERICEEYWRQGDREKDLGLEISPM
CDRTNVTLEKSQVGFIDYIVHPIFETWADLVYPHAQSILDQLEENRQWYQSRIPDEIDSA
RTEVGSTESGPSTQHEKQQSVDHLSEEEVENV
>A0A6I6MWF8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Terricaulis silvestris|TrEMBL
MSGQFILAQISDTHIRADDDGLSARQLERALAEAHEYRADVILLTGDLANDERPDEYDLL
ARIIEDVSRPLYLMPGNHDDRALIRNAFPRHGYLPRSGFLSFAIDDFPVRLVVIDQIVPG
ETHGLITHAGADWLDRTLAEAPDKPTIVALHHPPFLTHDMLFDNIGLLDADLFASVIARH
RQVERVICGHHHRVAVGQVAHAPVVIAPSTSWVYGLAMYPGQKIAPKTAEQPGWMLHVRS
DTGGLASHFMGL
>A0A517ZNN0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Symmachiella dynata|TrEMBL
MNRRELLQSLAVGSGAAFLSSGMGAPLLAADSSMPRKRTARLAHLTDIHLNEKRSAADGL
TKALRHVQALKDPPELLINGGDAIYDGLAVDRSHLESQWALWNNTWKAECALPVKHCLGN
HDVWGWDKPGSKTTGNEPGWGKQYSLDQLGLERGYYGFNVGGWRILVLDSMTADDETVYR
GELDAAQFAWLKNELTTTPATTPIAIISHIPIVTVGGLEFQEHVKQDPRKRRMLSHQDAT
ALVHLFRKHPNVKLCLSGHTHLTERISFSGIDFVNSGAVCGLWWKGNHYHTDEGYNVIDL
YDDGTFGTEYMSYGWTVG
>A0A839VTH7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Herbaspirillum sp. Sphag64|TrEMBL
MRVEILGCSGGIGGTSRRTTSLLLDDDILIDAGTGVTDLPLPALKTVDHVFITHSHLDHI
TCLPFIVDSVGEMRNTPLTMHATKETLEVIHRHIFNDDIWPDFTVIPSPENPYLCFNTLE
VGRSVVIKHRSITALPANHTVPAVGYQIDNLDTGATMVFSGDTTTCPPLWDIINNIPDLR
YLLVENTYPNSQREMAIHTKHFYSSLLLAEMKRLRVNPEILITNAKPVWFNQIEKELVQG
AGARKLRMLLAETILDL
>A0A3P7J903|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Strongylus vulgaris|TrEMBL
MSSFINFSVIGVVQMVNKHEGVFTKADEDSFEVFAVYCGLALHHAKLYDKIRRSEQKYRV
ALEVLAYHSVCNKDEVAKLQKMEIKERVEELETWKYRVALEVLAYHSVCNKDEVAKLQKM
EIKERVEELETWVFARYLRLPKDLTETFRFEFNYLRMSELEKPLYAISMFRTLFQDQFRY
DRDDLIRFVLTVRKNYRRVAYHNWAHGWSVAHAMFVLLMHTSRDIFNTHEALALYVSCLC
HDLDHRGKNNAYMKTMMTPLASIYTTSVMEHHHFNQTVTILQQDGHNILKSMTSSEYKQA
LSLIKHCILATDLALFFTNKAELNKIIDSGNYDIHHEHHRRLTQAILMTGCDLIASAKPW
YIQTETVKVIFEEFYEQ
>A0A380UA15|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acinetobacter johnsonii|TrEMBL
MTLNNEKNWTIIQISDTHLMDQDHLEFVRMNPEQSFHHVIQHIVERHPQIDAFVHTGDLA
QVPVPRTYQRYLDFMQSLKTPFYQVPGNHDNAEHFPFHQQQNKVHVIHFGPWSMVLLNSA
VKGKIDGWVDEAQLNQLEQILQEFAQQHIVIACHHHPFEMQSKWIDQHKLKNTQDLTAVL
AKYHNVKIVLSGHVHQESWREWHSIQFYSTPSTSVQFKPLSDHFALDEQAPGYRILQLNA
DGSHETHVERVLHAQQKINVEISGY
>A0A0N4XFB6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nippostrongylus brasiliensis|TrEMBL
MALYTAAAMHDYDHPGRTNAFLVAAEDKKAILYNDRSVLENHHAAESWRLLQLTENNFIE
TLDPAETKRFRYLVLEYILATDLKQHFEIIMTFNEKTSEMELQSESDRLLMAKMVIKMAD
INSPTKPYSLHRQWTDRICQEFYEQGDEERRRGMPITPYMDRDDAQVAKLQDSFIAHVVS
PLALAMNEAGLLPILPGLVEPEMMINLKHNHQKWLQEIDTSSGETARPARLEWVRKTNLI
DISCRLLID
>A0A0N4XXQ8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nippostrongylus brasiliensis|TrEMBL
MHVLLTSPVLTEVFSDLEVMAAIFAGAIHDVDHPGFTNQYLINSNNELAIMYNDESVLEQ
HHLAVAFKLLQDSNCDFLCSLSKKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKK
VAGNNVIVLDKYNDKIQLYRQWNSRILEEYWRQGDREKELGIEVSPMCDRGNVTIEKSQT
WADLVYPDAQNILDQLEENREWYQSRIPEEPESARQGNS
>A0A484NW83|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|plant metagenome|TrEMBL
MKFIHLTDTHLVADGGELYGTNPKQRLRQAIAHLLARQPDAEAVVVTGDLTHHGHAQAYA
HLRECLSALTLPVYPILGNHDSRVVFKEYFPGVAQDEHGFIQYSVDFGSHLALFLDTNEP
GVHWGVYCETRAAWLRARLAETDRPVLLFMHHPFFLIGIPSMDFLSLRDPAPLLAAIAGH
EARIRHVFFGHIHRPICGQYRGMGYSTLRGTNHQVALDLHGSAQCIIGSHEQPQYAVVQV
DAEQLLIHVEDYLDCDRQFLLHEMRDGAAGLK
>A0A0K1ZU69|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ralstonia solanacearum|TrEMBL
MVEMTAARGNKTVTVVQITDPHLFADRDSELMGYRTYPMLSKTIDAIRGHDFRPDACFLT
GDISQDESADSYELARFELERLGIPVFWIPGNHDDRGRAEAVFGQSERIHRLSKLTTADW
DFIHLETCRRGADEGYLSDPDFERFVSDVEASAGAGKQIAVVMHHHPVPTQTPLLDGYML
QDGERLLSFLDDQRQVRLVICGHVHGDYQLQYGSQTIEVCPATCFQWEKGTRTAKAEDWR
GFRIFEFSSAGYQSALISV
>H9TKE9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salmonella enterica subsp. enterica serovar Heidelberg|TrEMBL
MSDPVRITNPGAESLGYDSDGHEIMAVDIYVNPPRVDVFHGTPPAWSSFGNKTIWGGNEW
VDDSPTRSDIEKRDKEITAYKNTLSVQQKENENKRTEAGKRLSAAIAAREKDENTLKTLR
AGNADVADITRQEFRLLQAELREYGFRTEIAGYDALRLHTESRMLFADADSLRISPREAR
SLIEQAEKRQKDAQNADKKAADMLAEYERRKGILDTRLSELEKNGGAALAVLDAQQARLL
GQQTRNDRAISEARNKLSSVTESLKTARNALTRAEQQLTQQKNTPDGKTIVSPEKFPGRS
STNHSIVVSGDPRFAGTIKITTSAVIDNRANLNYLLTHSGLDYKRNILNDRNPVVTEDVE
GDKKIYNAEVAEWDKLRQRLLDARNKITSAESAVNSARNNVSARTNEQKHANDALNALLK
EKENIRSQLADINQKIAEEKRKRDEINMIKDAIKLTSDFYRTIYDEFGKQASELAKELAS
VSQGKQIKSVDDALNAFDKFRNNLNKKYSIQDRMAISKALEAINQVHMAENFKLFSKAFG
FTGKVIDRYDVAVELQKAVKTDNWRPFFVKLESLAAGRAASAVTAWTFSVMLGTPVGILG
FAIIMAAVSAFVNDKFIEQVNKLIGI
>A0A653HPR0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Hepatocystis sp. ex Piliocolobus tephrosceles|TrEMBL
MQHNLNNNKSLSNIKELLHNMSLEDENAMLEAFSLKNIKTIYDLISHVSCFKLTNFTDDC
NEVEEHDINSTIKENGTIKENGTIRENGTIRENGTIRENGIIRENGTIRENGTIRENGTI
RENGTIRENGTIRENGTIKENGTIKENGISSGTTIDTTKDMIDDTTKCIINGVSKIKTNS
ITITTTNNTETKQMYDFYVNLKKERMNINNKTEYKYFDIHINVEVIKLFPIKDNDKEKLI
NTIYEIINKNDILMICIYLNLINLWPQFELHNIHSINTFKKLINEKSNIDWIKKEVGVTF
LEFILIINFIINIKKKRIFCNNIFNKYSGENICEYKKRNTKSVCDKIHQFIEFDTWTFKN
IVDNPFFQRLRRLLQLGVCQYIYPGATHTRLEHSLGVGFLSSKYFNHLCNRSNLSSHHGE
LNRMLRCVEIAGLCHDLGHGPFSHTFESFFINYKKEDNDYKWDHANMSLKIVQHIIENII
DQDEVLSVDDIKIIQKLIKGGRDNNNNKSFVGIDPIDSLIEASYDIICNNRNGLDADKFD
YLQRDATIAPPNGTLPSLNCNRIIGQSAAINGHITYNIKDIHPVWSVYMNRYSLFKQVYT
HRKVRAMELMICDGFRLVDNIFKWSSSLNNLDKFLELTDYSIIYDIKRKAKKIKYDEKIN
HSLNLINAVIQDRNSEYVYKYIAETNITEPKLIEYLKTITNEERIAKYAYGLSPDDIIID
WNFLNYGMGAHDPLDYVYFYNSDNEDEAFIAHKEFRGTYPNHFEECNVRLYCKNQKVAHL
AKEAYTKFLTNDVFSGSSTFIKKKL
>A0A853SK47|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Janthinobacterium lividum|TrEMBL
MRTIVHLSDLHFGRVDADLLAPLRALVERLEPDVVVVSGDLTQRARSAQFQEARHFLDSL
PGPQIVVPGNHDVPLYNVVSRFLTPLVKYRRHVTDDLSPEYVDEEIAVLGINTARSMTFK
DGRISHEQIDFLRERLGSLPPGLTRIIVTHHPFDLPEHFDEDDLVDRAPQALQMFSECGV
DLLLAGHLHASVAGNTAERYKIAGYAALMVQAGTATSTRSRGESNSFNVLRVENSCIRVE
RYSWNEDSADFEKVSTEAFECQGGVWASLRPL
>A0A2X2WHH1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Citrobacter koseri|TrEMBL
MNTWESYQAVLDAIHAGQHEYDLIVATGDLAQDQTAAAYQHFAEGIASFRAPCVWLPGNH
DFQPAMYSALQEAGISPAKRVFYRRSMANLAAG
>A0A2X1WF19|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Photobacterium damselae|TrEMBL
MLTYSLPPRQSDSVVLLQITDTHLFANDAGSLLGVATKDSFHAVLAAIDHQARPFDAIIA
TGDISQDHSTESYQHFAQGIARWQQPCFWLPGNHDYQPSMKAVLPSPQIKPCEQVLLGEH
WQMILLDSQVPGVPHGELRAEQLEMLDRALAAHSERHALVLLHHHPLAAGSAWLDQHQLH
NADDFWQVCLSQFKMSFFFPRLKCLFLK
>A0A157NC88|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bordetella ansorpii|TrEMBL
MSAAHVTPIDEQPALLIQLTDMHLMDEPHAEMLGVDTEASLKAVLRQAVREMPDAQLVMA
TGDVAQDGSRAAYRRLRGLLGQLGTTVRCLPGNHDDVTAMHAVLPDWTTPITDVGAWRVV
MLDSTVRGSDAGHLDDTQLDLLDQAAATAGDRHMLVALHHNPVQMDSDRHDTMMVDNPMA
LFQRLADIPQARVVLWGHVHRQFDRRRHNLRLLASPSTCFQFAVHNGRHTLDGAAPGYRW
LKLYRDGSLATGVRRLHPATWHALCNAAQPRAA
>A0A157KKP5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bordetella ansorpii|TrEMBL
MLIAQITDLHIRMPGQKAYRIVETDQFLPPAVAALNALDPAPDVVMISGDLTDFGRAAEY
QHLKAMLDRLAAPYYLLPGNHDARAELQSVFDSHAYLGGVDGFVQYTVEDYPLRIVVLDT
VVPMQSHGALCERRLDWLAERLAEQPERPTVIVMHHPPFITGIGHMDAIGLLTGAERFEA
IVRQHGNVERIMCGHLHRTIFRRYAGTVASTAPSTAHQVALDLRPDGPSAFRMEPPGFHL
HEWRHSALVTHHAYIGDYPGPFPFHEGGELIDE
>F4N4R0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Yersinia enterocolitica W22703|TrEMBL
MFLTYISTQPTSAANKTSTNKCRNRLFSAGLTLSFSLYSTLAAAGFEVVALGVDGGVSDG
NLASYLIRDDSQPVYLALDAGSVLPGIAKALDKGNFSDITDEIAAPLTRQGYIFRQRINS
YFISHAHLDHVSGLIIGSPEDSKKTIYASADTIDVLRNYYFNWRVWPNFTDSGSGTRLGT
YRMQLLRPAQSLSLGLTRLTGEMYPLSHDKSPSSMLLITRNNEAFAYFGDTGPDEVEKSK
NLDTMWRKLAEKVKQQQLKGMIIEVSYPNEVDDGKLYGHMTPKWLLKELKNLEKYSGEGQ
PLKGLPVIISHIKPSLQQGQDVRKVIASELEQGNDTGVDFILMEQGDSRKF
>A0A518FWM5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia panareensis|TrEMBL
MPVHLPAQNRRQFLFTLGAGFLTCSAGAFAKDSQQSDVIYLLNDTHIGEKHPENSPVPSH
LRKVVSELVSLEQKPACVLINGDLALRDGQPGDYRHFAKLIRPLQKAKIDTHLTLGNHDE
RDVFYSVLQEEQPATPPVKSKHISVVQTQHANFFLLDSLHKTMVTQGTLGAEQRTWLANA
LDAHADKPAIIMTHHNPRLGGDPNHFPGGLTDSVELWEILAPRKQVKAYIHGHIHDRGNA
EHKGIHIINTPATSYVANPKQSTTGWTVAKLSPEGITLTTRTSDDQHPWNHQSKTLTWR
>A0A377WPI6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MLGINTWDSYQAVLSAIHASQRPCDLIVATGDLAQDHSSAAYQHFAEGIASFAAPCVWLP
GNHDFQPAMYSTLQEAGISPAKRVFLGDRWQILLLDSQVFGVPHGELSDFQLEWLEHKLA
EAPERYTLLLLHHHPLPAGCSWLDQHSLRNAGALDSALSAWPRVKHLLCGHIHQELDLDW
NGRRMMATPSTCVQFKPHCANFTLGYGVTGLAAGWSFTLTGR
>A0A378BPE0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MSAWPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVSPGWRWLELH
PDGTLTTEVCRLEGAAFHPDIASEGY
>A0A2X3CYL0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MIHAVSAHFRYPFPQPRREVVRLIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPE
EYQVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLF
IDSSHAGTSKGWLTDETISWLEAQLFEGGDKPGNDLYAPPAAAAGQCADGPDRLRKRPPS
AGAGGAFSVADAHLLRPQPQPDHDPVSPGADLHHSRTVHQVPYCHEDTRPYYDLSPASCL
MHRQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>W0ZB94|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium sp. C448|TrEMBL
MITANGVRIAEYARPSHQLLHLSDTHLRAGDDPLYGSIDASARLGRALAQIAESGTTPDA
IIFTGDLADHGEPEAYATLRALVDPWAERLGAPVIWVMGNHDDRASFRAGLLPDDTADAS
APLDAVYDIDGLRVIALDTSVPGHHHGEITDAQLEWLEVELAIPAAHGTILAMHHPPVPS
VLDLAVTVELRDQSRLASVLRGSDVRTILAGHLHYSTAATFAGIPVSVASATCYTQDLGV
AVGGTRPQDAAQAYNLVHVFDETVVHSVVSVGDTVALGYVDPAESARRIAAAGIVIPDSA
TRALRAERLHDSGRVVTNQPPTTPLPIVR
>A0A086M2A9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii RUB|TrEMBL
HAAVEWRQHYFYSKAVQTEFFNQGKAEKRLRLRISPCCDPVSTDVPKCQDGFISYISRPL
FEELALINTNGAIMQKCVPLLKANQATWNRIKTKGIEWNSAEALQEGFKTV
>A0A378Q6T4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moraxella atlantae|TrEMBL
MPNFNLAQIYADTILPQHAADYLSLVQISDLHLLTDPTAAFSGVYPSKHLAAVLAALGQT
EYDALLATGDLWQEPSTANFDALFAQFDTLGRPWAAIAGNHDVTLELDTHLAFEQWRRVP
IGADTRLLSRRLVQSAYWDLLFIDTSVAGQTAGAVDDATLAWLADILPQSTRPCVIFAHH
PMLAVGTPWIDRQGVQNAEQFWQVVAPFAQRIRAVFVGHVHQAQQVSAHGIAMYSCPATS
VQFTPFAADYAVQITAPQYRWIKLLNTGTLATGTKKVVVG
>I3WYJ1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sinorhizobium fredii (strain USDA 257)|TrEMBL
MTKFIVFTDLHMVPDGTTIIGIDPYRRLANGITHVNRYHADADRVVFAGDLTHQADRASY
ERLKDLFSELIPPAAIMLGNHDRREVFLEVFPEAATDENGFVQQVIDFADCRAVLLDTLF
APPYDYPMSHAGHLCERRLVWLDRQLGSAGDRPVLIFMHHPPHASGFAGIDMIRLINEEQ
FYGLVKRHGNVRHIFAGHVHRTISGSSRGIPFSIFKSPVHQQPMPFDIPDASLSVDEPAA
YGIAVITADGVLVHTEDYEIARRDAVEA
>A0A0A7LF14|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Methanoplasma termitum|TrEMBL
MKFLVVSDIHGNTAVTDWANSIADEEDVDFIIVLGDITDFGPEKVAEKILAPLERDVYSI
PGNCDPPSVHDTISGWTVDMHGKTTNIDGFYIAGLGGSNPSPFNTPFELDEDSIYKILKP
ISKEGMILMVHAPPYGINDMIPAGFNVGSRSILKIVDEFRPILVLSGHIHEDYGAKYVNG
TTFVNPGPAKDGMYAIVEIDGGAVKAELFTVSG
>A0A7D3VTN9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Actinomadura verrucosospora|TrEMBL
MLTFAQLSDIHLDGGERARERAHRVMRHLDGLPLDAVLVTGDIADHGAPAEYEEAREVLR
SPHPVLTCPGNHDKREPFRKALLGEDPSGEPVDRVHEIGGAVFAMCDSSVPGEDHGFLSD
ETLGWLDGVLGDRPDVPAFVCFHHPPVTLGVPYVDGIRLFGEDRLAAVLARHPQVAAVLS
GHAHTAAATTFAGRPLLVAPGVVSTIRLPGQDGAVADYEAPPGVAFHTLDDERRLTTHYR
PIIGGSSTSA
>A0A1I7W8S3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Heterorhabditis bacteriophora|TrEMBL
MMIVGDTFGFYQLVLRKHSCRLRYILHQLNSGQLPLEDLKRNIEYAALVLETAYMDETRR
ICDEDDDLAEVTPETVPDEANMQVREWLAATFTRQNAGKKREKPKFKSVANAIRTGIFFD
KLFRKQQSVQCPIPLEISELLRVEIIPLHALENYLHALEQGYSKHNNPYHNVVHAADVTQ
SSHFMLSQTGLANSLGDLELLAVLFGALIHDYEHTGHTNNFHIQSGSHFALLYNDRSVLE
NHHVSSCFRLMKEDDKNIFLHLTRDEYRWVVLFLLIFNITTNILFAYLRRRRTKESGSIK
SDWKRGSTRKRAKL
>A0A086P4F9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sphingobium herbicidovorans (strain ATCC 700291 / DSM 11019 / NBRC 16415 / MH)|TrEMBL
MKEGRNGMLIAQVTDIHLGFDPGNPAELNRQRLDQVLRALIDGPNRPDLLLATGDITDHG
DGDSYRALAEAFAQCPFPVWPAMGNHDDRANFAAHFPHVPQDGGFVHYVVPLPGRRIIVL
DTLEPGRHGGAFCEARAAWLTARLDEDATIPTLIVMHHPPVEVGIDWMNTHPDEPWVQRF
SAAIANRPNITALVCGHLHRTITAPWKGTTVAICSSTAPQLALDLRPMDPDAPDNRPMIV
ADAPAYALHRWTDAGLVTHFETAGEPATLAKFDAGMQPLVRMLMAERPG
>A0A024HPR3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas knackmussii (strain DSM 6978 / LMG 23759 / B13)|TrEMBL
MPAKSTSAQESLLLVQLSDSHLFAEADGRLLGMDTADSLRQVVSQVLGEQAEIDLVLATG
DLSQDGSVESYRKFREISGAIAAPTRWFPGNHDELAPMREVCGDADLLDAVVDLGAWRII
LLDSTIPGAVPGQMTAEQLALLDEALLAACDRHVLVTFHHHPVAIGSQWMDRIGIRNPDD
LFAVLDRHPQVRCLLWGHVHQEFDQMRGDVRLLASPSTCVQFAPGSEDFCVDSLAPGYRW
LRLYPDGRLETGVSRVTGIDFQVDYSVKGY
>A0A086QGQ9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii MAS|TrEMBL
MRLREHSLLLCVDAMSRDSPVASPAHSGVFGPSADAEVSEVFSLPSLSAVPGAASASSLS
RENSLVSSRRASPSVSPPAGSPLWRLVRRCGQGEGERENVERCRLRERREECGAARRGPP
ASAATSDCSCPSAGDRRRVQSRRRRARTFQGRSFCGNHVSTEAERDGETEGEEETEGEEG
REEYDSKRRGRLARRLGRRFVIAAAERGRKREGEETIVLRGNQGECWQEAQRPADSPDCS
SSSVCCFGGSCSTSSQCCACMRLASVSCPSPRSSFSTFHCSLPAVSSASAAFVCPREPPG
SDSNSSPSCASSRGFSPSSPKATVSSSRPSSSSASPLRSSLSAPSGLFPVGSGCSSDVCV
SVPLPAMFRGCRVHSSAPSSRTEQGTALLTGAPPSANELEAASAMANPTNSSRFSRVKTV
SFATLSECGSSHISRRSDSASEPEAEREKPGLCSMRVARRESSPAARSPGRQSERRGTDS
SCTSLPQRSDRAGRDRVGSRGSAEQRSSTSSRRVSDHSRAEAGLWSAGPGDSGASLEPDL
ESRSAFLRRCRARLAAARRKVCQAFQSLAEHDLVFRMKEDLAQMRHESSLRSVFADGCRE
RSGVEMSERTRLSVGGGTGRHLSVGTSTHKEGSTHKEGSEKERIRDGGSASPSTHLSRSG
SGDVILRRFPLKFVDRGLEDLFADNINRWMATRLLLMGVLSLVVTSVMWPLMAWSFNLLD
AFNHSEPLGILFHINMAVTVFVAVLFIVTKRCRHLAEHAELIADGGTFLVVTIWGIWNTT
ASYILEHSYVQDVIGSAYPMHPADAPISLEKTSAWSTSLEASSAVAYLYGLLLIVQLDVV
YPSRTRRTWQVHLMFFGFSTASIVIRGALNPDFVPVPFVVIRALTYLMLTVFLFIGRHAT
ELQQRHTFYNWL
>A0A086QXD6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii MAS|TrEMBL
MKVSPHRTSERGSSPTGGENGKHRFTQSGALRRQSAAPGGAKRSTMTGFLKAEPNPGSET
QDLEATQRRLKSAHRRTMLPTWILTGLSLAYVLFEGGRLLYETTLQQWSEEAILHIDKEI
FFLHDFAAGFYSLAEQLTSDYCFLNFMNAHSPPAAPTSTREEVQNLISGYAPSFCSWIKD
LYFFEEPLADTADRSTYQLLNTTYICGERFADLVQRINGNMVEVVQNYTLVKMRLIEMLA
PLVDNRNWSPHLLCDLDFSAGDLWACHDGLTALEQLRGQLSGYLGREWHLYSPILSIVIV
FILATLFFSRRHAFNAVFHTRFESLWAMLQQIDQV
>A0A449H7J1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nocardia farcinica|TrEMBL
MILVAQVSDTHFDLGARNNERVERVMAFLADLAHRPDAILVTGDVTESGKPEQYAEARVA
LQADIPVWAIPGNHDERAAFRTELLGEQPSDSPINHVHRVGALTVIMLDTTIPGEPGGRI
EEDTYRWLREVLADAPATGPIVLAMHHPPARLHSPIVDDIALAEPDRLADVVAADPRIRA
VLTGHAHSAAATTFAGRPLLIAPSTASVLGGAWEVELPHRVMDYAPDPAVALHVFDESGS
MTTHFRTVPMGGFLGVAPV
>A0A1G4H5R6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Plasmodium vivax|TrEMBL
MNMQCNKTNPTCEISSVKDFLRNICLDQEDKIVQNLELRNVKTVYDFLRHVSYLTVTSCT
GMNNDENVDITSQSNVKFASAHESIFQNGVSVNGKLTQQLAQQLAQHNGDGGNPGEAQLC
NGHTSAGREKGDRCNGVQRNGPQGGGKLANGVSGIGVSSNGVSSNGMDGSAGRDDPAAHS
ESTQACKEIAAMRDYYEQAREKRSGAEKKGEYVYFDMYIKSEVIKTLPTTDRDKERLINY
IYKVMDVNDLLMMCIHFGLPHLWPKFEQSNIRNVELFKRIIIEGRKFERVKNEMGISFSE
FVQIVNFTLSVKKKRIFCNNIFSQFDPCDCKNKKKHTKTICDKIHQFIEFDNWTFKNIID
NPFFQRLRNLSQLGVCQFVYPGATHTRFEHSLGVGYLSAKYFAHLCNRYNLSPYSGELNK
MLRCVQIAGLCHDLGHGPFSHTFESFFMNYKKEETDHKWNHASMSLKIVEHVIENLIDQD
DVLDSTDIKIIKKLIKGREHHKSVCGVDPVDSLIEASYDIICNNRNGLDADKFDYLQRDA
TIAPPNGTLPSLNCNRIISQSSVINGHITYNVKEIHPVWTVYMNRFSLFKQVYTHRKVRV
MELMLCDGFRLADDIFKWSESLHDLDAFLDLTDSSIIYDIKKRANKHKYDEKVQKSLNLI
NSVIHDRNSNHAYKYISEINLSEPQLIKYLKDIANEERIARYAHGLSPDDIIIDWNYLNY
GMGANDPLDSVYFYSSDNEDEAFIAHKEYRGTHPRYFEECNVRLYCKNKMVAHLAKDAHN
KFLSDVFSESSPLYKKKIVK
>A0A086LAH9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii FOU|TrEMBL
MKCADLSHCSVPWSQHFQWCQRLSVEFYDQGDEEVARHLPMSPLCDREKHSEVAKSQLGF
MSFVAVPLFEELMAIDGTGNIEKYCISVMKTNASHWEALSSAAVPVPLLGEAPSPDVAPP
LLHLIDGSGAAAVHPGSKAAEIANRYASSTVTTLDLTCLVYRTQLNRARRSSQQSGRRVS
EGTSA
>A0A378RGU2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mycolicibacterium aichiense|TrEMBL
MTGDPHQMSRRQLIRHGAWFGAAVGLAVVGGEVLSHVASAPAATGTRPTLRFAQISDSHI
GFTGTANTDVTGSFERAIRQVNNLGYTPDFVIHTGDLTHLATPAQFDQVNQMLGTLNTPH
VFTVPGEHDSVDDAGQKYRSVFGAGTRGDGWYSFDIAGVHVIGLVNTLNLKKLGHLGADQ
LEFIEKDVASLSSDTPIVVLSHIPLFAMYPDWGWGTDDSTQALSYLRRFSSVTCLNGHVH
QLFVKTEDNVTFYSATTTAYPLPHPGDGPAPKPLTLPAGRLHDALGIREVSYTRGQNVLA
LKEQTLQ
>A0A076LF52|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Edwardsiella anguillarum ET080813|TrEMBL
MMQRMWRRWVAGGALLCGLAMCPAQAAFELVALGSGGGLNGDNLNAYLIRHERDARYVAL
DAGTTLPGIARALELGAFPTVSAARAAPWTPQGYVLRELIAAYFISHPHLDHVAGLLLAA
PEDSHKPIYTLADSADTLRNHYFNWKSWPNFSDAGQGQRLGTYRIHSVRPGQRFTLGVSG
LRGVVYPLSHGGETSSMILLEREGEYVAYFGDTGADRIENSQRLDHIWRRLGPLVASRAL
KGIIIETSFSDEVPETRLFGHLTPALLNQEMINLSRYSGGTAALAGLPVVISHIKPSLRA
GAAAEQQIMAQLAVGNRSGVAFRHLRQGERTRFAGGDE
>A0A6N3DAB3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Eubacterium limosum|TrEMBL
MKTITFAHLSDLHILKDYGNSMFKDMVCHMEKKPCEVLEGIAGWLRGNAGKLDFVLLTGD
LVHEGGADEYRYLKMLLEEYFDGTPVCPVLGNHDRVAAFHEGYENREPDTEPVCYAREFD
GLQLIVLDSSVGCDATHHSGRFDEAQFVFLEKALEKKMPRGHIVAFHHPAFDEWADERVS
AFGVEGSERLKEIISGKNVLALLSGHTHENINTTFYGVPAYTAESTAFGVAINEKGMYMT
PAAGFNLCTVTDRTLRVETMSYPPNDQPITEPIPLEALGQMMKNA
>A0A8C8GTD6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oncorhynchus tshawytscha|TrEMBL
HPPPKKKKKNTNKKCKKYIQFQSKVWTHLLIQILRCLVKQLDKGEVNVVDLRKNIEYAAS
VLEAVYIDETRRLLDTEDELSDIQTDSVPMEVRDWLASTFTRKMGVVRRRPEEKPRFKSI
VHAVQAGIFVERMYRRTSNMAGLTYPPAAIAALKDVDNWSFDVFVLHEASSEHALKFLVY
ELLTRYDLINRFRIPVSSLVSFVEALELGYSKHRNPYHNLIHAADVTQTHWLTELDILAM
VFAAAIQTLNTLGQPTTFTFRPGVAILYNDRSVLENHHVSAAYRLMQEDEMNILVNLSKD
DWRELRTLVIEMVMSTDMSCHFQQIKSMRNALQQPEGVDKAKALSLMLHAADISHPAKAW
KLHYRWTQALMEEFFRQGDKEVELGLPFSPLCDRKATMIAQSQIGFIDFIVEPTFSVLVD
TTEKIITPLIEDTLKSHDTGVRRSSLTGSGSVTVVESVQKHSGRGSSQGVDQGLTTDYSL
TGIDLKRVRHTLAEVIQHNKDRWKELSVQGIVVFLLLLFFIFFFLVFFSLLNTFPSFSVM
FFTLS
>A0A7U7J516|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Contendobacter odensis Run_B_J11|TrEMBL
MPTANPLRVIQITDLHLKAQPGSRLWGVDVDAGLNAVLARIREQHPQADFILATGDLVGD
EPEAYIRLRQILESLGVPVYCLPGNHDFPGIMGRVLRGGSVRMERYLVADHWQFVLLDSS
FPGTPGGHLAPGELALLDTALALHPELHTLVCLHHNPLPVGTVWLDTMTVSNGEALFAVV
DRYPQVRAVVWGHIHGEFAARRGTIQLLATPATCIQFKPGALEPEADELPPGYRWFELYP
DGGLKTGVERVEWPVRPHGLTRRVPA
>A0A3R7YMG0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii CAST|TrEMBL
MGRLRSAATRMATRAGRRNEADGALEEGNDLEGRPGAGEASTPHNRFGLVGLSEPRDDLR
RPLDAEPFVPKHSAGEFPGSCKFQGRSARLSLNSTVLGEDCPMRLRTDGASPDMKVEEGE
SGTGVPLPAVSRLCTSPRVLWGLNSGLSLLAGSVLQGAGTEKAGRNLSTKVSFEATRKDS
RRDSMRLAFSKQGANGEAGRLQSVAVREEPERLVSTKVRDVCTRSSPHESSSSRRAVTIR
VDGSVVDSVELGCRTWNGCETPTERGVKERKKERKKEREMEEKEEEEMLDTDTPPHLRGR
GTLEALYLKWSKHSVYKFFSEEDRKYFDMATTGIPCYFSSKNLERSYALYRCPALSGYLL
LFHTAWIICTWTIYCLCVLTRPAVTSSRRMVAPFVVSWMISALSIFVVFLWRQTGGVAVE
RFNRKEKELRKAEEGAVPMYEAYHWRPCFTEDFGTASIGLATITPVALAAAVAVWIGLDP
YIINDYGESSSRLAPPLLDTSFGLAGFVASQGYIAFSVLFLTVSVICSGIRLRKMLYVAV
GNMISVLTALISFAFAYKDYTLFLSTIFYTFTVIPVSLYHAMKGERLRRFLFFQRERARY
GQDIGAEATGASGSATLVEELILLINEAGLKIRHARKKMKYKKCTDLIESEGMLIRYADF
HLFSSPIEF
>A0A1V5XCC4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Deltaproteobacteria bacterium ADurb.Bin207|TrEMBL
MALQNTTRYGSPMTLRIGIISDLHFGPRILFHGRLRKMSDMAPELTVAFVQRMNELKPDL
VLTLGDIIEDESLETDANRYRHALRLLSEINAPVRHVCGNHDTINQTDDMIREAWNHQGE
LYYSFDCKGYHVSVLRTVERPHIDARLPSEQLEWLRKDLEQTTLPTVVAMHHGAADQNLR
NNPWFENAPEVALIKERKALRSVISSSPRVRLVLNGHLHWTHVGIHDAIPYVTVQSLTEN
LDPDAPGRVAAAWALVELSDHHVLVRTEGAAPSVFESSLP
>A0A812C141|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sepia pharaonis|TrEMBL
MLSSSVSPSVLFRFVCYPLPPHMISSSASPAIPFHHICYPLPPHLLSSSASHAILLRLTC
YPLPPHLLSSSAAPVRSKFFSLIEDDVSNIMVPEQNNIVRSILMTTCDIAAITKPWEVQR
QNLFVEIEENISRSKTDQAVVNLILHDRRNEYYLAFLLIFYLSYFLSLFLSFFLSFFLSS
PYSPGFLNLFPFHSFFVILPYPIFSRPFPLSFFSFFFFLKSNTFFFLFYFFPPLISFLPL
HRHISISQELTIFLFFSCFLRLCEFRCQIKSSLKIVSLILLLRPCLFSFFKFNLLFLILN
QTRHRLEKVNTSKTQLRAKHMTESLFPFKIISSPFFIFEKVYFTSFFFHSFFVSFFLFSA
YSSDLLTHFLSFFRFYLFISIFFSPLFLFFLSFFISFFLILPCPCFSFSFLFFGFSSSSF
LLTFVSILSFFIYFFLSNSALSIFLLTFVSILSFFLSFFSNSALFMFLILFFFFSVFPHP
VFFSPLFSSSSFLSHLLFLFFLSLFISFLSNSALSMFLIPFFFFSDFPHPVFFSPLFLFF
LFFLSFFLSFLILPCPCFSFSFLFLDFPHPVFSHLFSTFVSFLFSFFLSFFLILPCPCFS
FSFLFFGFSSSRFFFSPLFLFFSFFLSFFLSFFLSNSALSMFLSFSFLFLDFPHQFSSHI
CFYSFFFFFISFFLFLSFFLSNSALSMFLILFSFFFGFSSSSFLLTFVSVLSFLSFFFFF
FLILPCPCFSFSFLFFRIFLIQFSSHLCFYSLSFFLSFFLSFFLSNSALSMFFSFSFLFF
GFFLIQFLLTFVSILSFFLLSFFLILPCPFFFSPLFLLSFFLFFSFLYFFLSNSALSMFL
ILFSFFRIFLIQFSSHICFYSFFLSFFLSFFLSFFLSFFLILPCPFFFSPLFLFFLSFFI
SFFLSNSALSMFLILFSFFRIFLIQFSSHLCFYSFFLFFFFLSFFFLNLPCPCFSFLFFF
SDFPHPVFLLTFVSILSFFFFFLSFFLILPCPCFSFSFYFFGFSSSSFLLTFVSFLSFFL
SFFFFLSFFLILPCPCFSFSFLFFRIFPHPVFFTFFFSSFLLTFVSLSFFLFSFLSLFLS
FFLILPFPCFSFLFFFSDFSSSSFLLTYICFSFFLSFFFLSFFLSCLSFILFFFFSDFSQ
VFCLCFFLFFHFFFLSIFFFLIFLSMFSFSFFAHLVFFSPLFLFFLFFLFSFFLFSNSAL
SMFLILFFFFRIFLIQFFLTFVSILSFFLFFLSFFSNSAFFSSSSFLLTFVFFLSFFSFF
FFIFFLSNSALSIFLLPLFLFFSFFLSFFSFFFSNSALSMFLISFFFSDFSSSSFFLTIF
SFFLSFFFLSFFFLSFFLSNSALSMFLILFFFFRIFLIQFFLLTFFVSFFLYFFFFLSFL
SFFLLILPCPCFSFSFFFFSDFPHPVFFSHFFLLFSFFSFFFLSFFFFYFSLILVHVSHS
LFFFSVFSSSSFFSPLFQFFLSFFFLSFFFFLSFFSNSALSIFFFICFYSFFLSLFLSFF
LSFFLSFSFFLILPCPCFLISFLFRIFLIQFSSHICFYSFFFFLYFFLFSFFFLSLFLPF
LSNSFSFSFFLFFGFSSSVFFSFVSILSFFLFFFLFFFLSFSNSALSIFFFHFLSLFLFF
LSFFLSFFLSNSALSMFLILFSFFRIFLIQFSSHLCFYSFFLSFFLSFFLILPCPCFSFS
FLFFGFSSSSFLLTFVSILSLFLSFFSNLPCPFFFSPLFLFFLSFLFFSFFLSFFFMFLS
FPFPFFISFLSFFSFFLFSSFFFSFFLIALFVSHSLPFFRFFLPVFFSPLFLSFFLF
>A0A085ESD4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Devosia sp. LC5|TrEMBL
MTLKFVVMSDLHLLPEGELSLTLDTSARLERAVDEVIARYGDADFCVLAGDLADTGNPAA
YERLKTIIARLPIPVHITLGNHDDRQTFLDSFGAQFAGETGKVDKVIDIKGYRIILLDSS
EPGRVDGVLEANQIDWLIARLAEAQDRPVIVILHHNANALHIHADTIRILEPDAFIAALK
THPDIRQIIAGHVHLTSTAIWHGLPFTTLAGGHYSVSFDVDRPEVPLRRLEGPGQMAVVV
GTPDRTTVLFDDFINGNSVIDTVHV
>A0A1L3KZL5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sinorhizobium americanum CCGM7|TrEMBL
MRCRIATTLMTKFIIFTDLHMVPDGTTIIGIDPYRRLANGIAHVNRYHADADRVIFAGDL
THHADRASYERLKDLLSELVPPAAVMLGNHDRREVFLEVFREAARDENGFVQQVIDFPDC
RAVLLDTLFAPPYDYPMSHAGHLCDRRLAWLDRQLGSAGDRPVLIFMHHPPHASGFAGID
MIRLINEEQFYGLVKRHGNVRHIFAGHVHRTISGSSRGIPFSIFKSPVHQQPMPFDIADA
SLSVDEPAAYGIAVVTPDGVLVHTEDYEIAKRDAAVA
>A0A2T6J5R7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii TgCATBr9|TrEMBL
MWFYSYLRHPNDVPSLCTHIRSSNIFLRLGPQYYLPEDERKSLFVRTCHLLYYLASLLFL
TTLTTYTAIKIPSSPSTTTELLSQLFPFNSIDDCNERLSCKVDCVLYAFPDLNCAKDDGS
LLTFGGNSYSSLYFYHYPGKDVPLQKEARTAWERCYQIMRETTGRLQFLQQDRETVERTH
TCFAGCKTNGAVTFTQKLTDGTPVVFDSGTDWLQMAPAGSLPQDTRPACNPSEPPSLLCV
EPTDECQHVTLRYQVCIGDTAFCFDIVRILITIALGVVWNVVLDAFVVWAMSIDDSDPQN
LGRVASKCGLQIIATAIIVSSFFCLVASMTRILSMDANIARHGTLWTSFVLVIIIDQLFS
FLFSVLIWYAMLRRCGRQLPDESRFQYKIHPSPVLVKLKKATRKIVNYNGFEMFFTMLLG
WMVVDLTCRMILCQFFFDETAFLNQADRILEVVDFIILILFIVEICLRIAADGLKIYFSD
PINCIDFFLVFFGFGIRIVDFFIQINKGIGNVLFIMRLVRLYRLHRPPTGSLAIGKKEVF
TSRVERIIAVLNKALEIEELTTREKDSLKWLIQTISSGKLYEMGSEEKKKTDSHVQAWIS
IISTQSQSANQMADDMENILLERVKQMTKAGDAETDMPAVLQLEYGIDVSLDHAIEGYLA
NNLITWNFDVFRFHVIAGRAALPKLFVRCLQHQEVCSLFNLKIENMLRFAMELEKTSFST
TPFHNSIRSAEVLQAMHLFLAFFDTQIKGFFNSREILAALLAAVVWDYQHPGFSSAFLIK
TQHAIAIRYNDRNVLEHHHVAAAFSLMQKLGENDPLLAFPEDQYIALRKIIIQLSQSGSR
SNQTACLSLLKTKLQQAEFPRSITEDKNIILCNLMNAANYSFLGRPLQLYLQWSQKYMEE
LFMQGDRELELDMPITKNCDRHTTSEAVVQLGLIDGWAIPIYTTLAQTVPKLNAIVVSHL
RRNRLHWLDEQQEEDKSKEKQTKVTPIKRYSKTKQGSTEATGNGELSKPEATTIEIADGT
AGVPELRANANPLSEVD
>A0A2X4V2S4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serratia plymuthica|TrEMBL
MLGAVLLRYPNVNTVVCGHIHQDLDLEWQGRRLLASPSTCVQFKPHCTNFTIDDVSPGWR
YLDLLPDGRVETQVFRLENDDFRPDMDSEGY
>A0A4U8W565|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nocardia cyriacigeorgica|TrEMBL
MGMILVAQVSDTHFDLGPRNVERAERVMAYLADLRRRPDAILVTGDVTDSGKPDQYAEAR
IALQADIPVYALPGNHDDRGAFREVLLGVSPSTEPINHAHRVGPLTVVLLDSSIPGEPSG
RLTDDTYDWLRTVLAEAPADDPILLAMHHPPAHLYSPVVDEIALADPGRLAELVAADDRI
LAVLTGHAHSAATTTFAGKPLLVAPSTASVLGGEWELALPDHVMDYAPDPAVALHVIDEN
HALTTHFRTVPMGGWIGVAPY
>A0A379LV59|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodococcus gordoniae|TrEMBL
MGSSPAPERTAEYPRPSHTLLHLTDTHLVGGDELLYGTVDADTRLGLILEDIRASQVRPD
ALVFTGDLADRGQPDAYRKLRRLVEPLAAALGADIVWAMGNHDDRAVFREELLDEAPAGA
PIDEVHRVGGLRIITLDTSVPGHHHGEVSAEQLAWLADELSTPAPFGTVLALHHPPVPSV
FDMAVLVELRDQAGLAEVLRGTDVRAILGGHLHYSTSATFAGIPVSVASSTCYTQDLNVP
VGSQRGHDGAQGFNLVHVYPDTIVHSVVPSGSYATAGQPHTAEDAARRLAEAGIRIPENP
DLTVRV
>A0A6J4SYH6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Solirubrobacteraceae bacterium|TrEMBL
MTRHFLIPLLLCAGLTSGCDAAKSSGAAPSGSTLVSTVIDADGDARLERGPGEPLKPRRE
LLRSAPADPTAAAPSTFAQITDLHIRDEESPARVTFLDRVGEPFTSTFRPHEALSHQVAT
ATVRALNSFDPQAVVVTGDLIDSAQSNELDDALAVLDGGQVRPDSGARGYDGVQEASNPD
PLYYRPDSDAPRRPGLLERAQAAFESPGLDAPWLPVLGNHDVLVQGEVAPSASLDAAARD
DRVFESLQPGAEPPTGDEDPAAAVEALLDGRIPARERRVPADPDRRHLTPAETARRLGRS
LRAGRLDYTADVGDRIRAVVLDTARREGGSGGVVSGGQVAWLREQVARAGRRWLVVFSHH
SLETSDGGEAALAVLDAAPRVAAAVSGHRHYNSIEPRETARAGYWLVSTASLADFPQQAR
AFSLRELTDGGAVLETWMVDHDGRGLAGDARALSFIDAQGGRPRGASGTAADRNAALHLP
PAA
>A0A2X2VCV5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cedecea neteri|TrEMBL
MEWLERQLAAAPERHTLLLLHHHPLPAGCSWLDQHSLRNAAALDAVLKPWPQVKTLLCGH
IHQELDLDWNGRRMLATPSTCVQFKPHCANFTLDTIEPGWRWLDLYPDGSLTTEVCRLQS
GKFSPDTDSEGY
>A0A1X6X136|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Brachybacterium nesterenkovii|TrEMBL
MRILHLTDTHLFADPAARHYDRIDTAAALERVLERLADIAADRPVDLVLHTGDASEDASE
DSYRRLHAMLDPVAAALGAELLVVMGNHDSSAAYATVAGPGDHGGPWQDRARMLANAWRA
VVLDSSVPGAGYGRLDAAQLAWLREVLAEPAEHGTVLAIHHPPLTAATPLLRALDLQDRD
ALADAIVGTDVRLICSGHYHHPMTGALAGVPVHVAPGVTNVMDPLCGGGREQARALSGAS
VIDLSDTGDDADASAVPVITTAVWPNAGDVLGDGEVPVYDFSPQQVAAIIAASVPDGAV
>A0A1E1FPY6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas chlororaphis subsp. aurantiaca|TrEMBL
MPSVSTLTTDDPVLLVQLSDSHLFAEADGTLLGMNTRDSLQRVIELVLEQQPRIDLMLAT
GDLSQDGTLESYQLFRDMTRQIPAPARWIPGNHDEPQIMAQAATESSLLAPVVDIGNWRI
ILLDSAVPGSVPGYLQDEQLQLLASALSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPH
ALFAVLERFPQARAVLWGHVHQEIDRQQGSLRLLASPSTCIQFEPGSEDFKVGETAPGYR
WLRLLPDGRLETGVERVTGFDFQVDYGSDGY
>A0A8B6LQ45|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Variovorax sp. SRS16|TrEMBL
MTTFLAQLTDLHIREPGRLAYGRIDTAPYLQRAVQSVLRLKQRPDAVVITGDLTDFGAAA
EYAHLQELLAPLSMPVYLMPGNHDDRDALRAGFPAHAYLGQDGFIQYAVRVGDLRLIAID
TCVAGHSHGALCAQRLAWLAEQLALYRDEPVVVAMHHPPFETLIGHMDQIGLLEGAEALE
ALIAQHPNVERVICGHLHRAIDVRFGGSIASTAPGPAHQVCLDLAPDAPAAWMLEPPGFR
IHAWRAGGRLVTHLASSGSFEGPYPFNDDDAPID
>S8F3Y4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii (strain ATCC 50611 / Me49)|TrEMBL
MHISCVKGRIVARQIDNVFTVIFAIEVLGKFVSYGLEYLQDPIESFDTIVVLTSFTLLVL
GFYVSGIGLLRILRLLSALALLHKYPDSKEKRPELSAGNSSKLEKASSIVEGLLTNVHIP
KYFKTELEWVWDSILANKVYDSHVVENEEEEEDQATETIIAGSDASRKTQAAVRASRAQS
RASKLPHGSSSMVVGTTNGRMSGQILETLREPDPRMMDAALYKSETRNLDPLTATVGGMK
NSPSMFAKGSKSSNMMGSSASKSFRTERNKKAIDIISVLYQASQITGAEQEQVNEAMRPF
DEWQWDALHAGDVCDMNLLPVVFVRAIATFPTIMTKFNFDLDRLFDFLKVVQTSFQKNVK
FHCAAHTADMIQAMHYFLTIGKLGALLSEYDVFLCHFCALVCHFGHPGVTNTFLVKSRHP
RAIRYDDESVNENYVASAISCLVAREEYNFFGDKLPLWQVFRLHMIDILLNFDISKSAHQ
VAMFRTKVSIKFTASTPADKQLLLTILLRAADYSFTCRQLALYSKWKDRMIDEFFAMGDT
EKQLALTVSPFCDRELTNVDKCHVAFAEVAVKPLMTVLVLGLAPHLQKDVLDTLEANQKN
LMQKLDKSD
>A0A165S2G8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oerskovia enterophila|TrEMBL
MTQTMDTPVRPVRRSVPALALLTLVGGLVLAATPTQDASAATAPPAPLLTTADTTWKYLD
DNTDPGTPENLLSWTQPAYDASAWKSAKGSFGAKGGKLAAVGPHTPTTLLTQYIEGTTTD
VPTFFFRSTFEFDADTAAELEKVVGNVVYDDGLVVYVNGAKVAGFHDERVTSTTTNLQYA
GSGASDPVAASFDLDPEALLDGTNTIAVALYQDRASSSDVYFDLTSLTPVAEDAPVVVAP
PTRVILTPTETPETSQSISWLAGSEADTTGQVEIRPASGGATRTLRAYAAGAVNGNAKQH
FSVTVPGLKPATEYSYRVGVPGAWTGWKTFGTADPAETDFSFIYYGDAQIGLDSTWPKVV
AQAQATAPDAIGSVHAGDLIDSASNETQWVNWFKGMENAAATSNVMAAPGNHEYSGDKKL
AAWKANFEYPLNNPTTETVGELAQLAVGDTPVARQYAAYFAHWSEFAAETVYFTDYQGMR
FITINATRDTAFLTPDALPACTGTDCPQAKVAELWTQFQAAWLDTVLTESPSKWNVVTFH
QPVYSTSSGRDEPVLRKYWVPVFQEHDIDLVMMGHDHTYARGYNDEDRTDTEGVTDGPVY
IVSNSGAKHYDLAAPDKNVWTNNGATQVLRGEKITTYQVVDVTADTLTYKSYIAEKVAGA
STDLPVGAVYDEFTVTKRDDGTKWVTEAGVAVPSEVTFTTQPAAAVTVESGKNVTISSTA
VSTSTATPAPRVAYQWQTAAAGTDAWTDIAGATSKNLLLKKVSATTDQHRYRVVATAGKS
STTSAVSTVTVTKAPTTLKLAASSLRTGAKPRVTANASVAGTVEVTVVSGMFVTTTSVPV
AKGVTTTVTLPQSLPFGVSGATVQVTATLTPTDSVELAGTTAGFTTTIG
>A0A8I1C976|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Helicobacter pylori|TrEMBL
MQVYHLSHIDLDGYACQLVSKQFFKNIQCYNANYGREVSARIYEILNAIVQSKENEFLIL
ISDLNLNLNEAEYLQDKIQEHRLQNKNIQIQLLDHHISGKEVAESFHWYFLDINRCATKI
VYEFLKKHYALLEPKNTTWLEPLVEMVNSVDIWDTQGYGFELGKVCMRMITQSSELNRFM
FDDENRNYKLKLLEEVKNYLFLENAPVAYDNDLFKLKKIALGGDPDTETMDNISSNVQTH
LLSLKKHDCSVYYQDKKGFLSYSMGGISVLANLFLTQNPDFDFYIDVNSKGNVSLRANGN
CDVCELSQMCFNGGGHRNASGGKIDGFRESFNYRDIKEQIEEIFNNA
>A0A182AU19|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cyanobium sp. NIES-981|TrEMBL
MHVLQLSDPHLLAGPTDTYRGRRPMQWLAQGLRESLALVPQPPDLLLLSGDLCQDESLGG
YVNLRRLLEPLAIPLALLPGNHDHPMLLRVALGRTAVIAPALLQLNGARLLLLDSHKAGA
TAGWLGTAQLRWVAERLGQLREDPARLPLLVAVHHPPVPIGDPVMDAIALLDGQALLRQL
RQVPELVAVVFGHIHQHWAGSVPGRPEVPLLGCPSTLCGFGPVQPCPLGRPGDPGGRWLV
AMPEGGFEESLLRWLPP
>A0A7W8KY91|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mucilaginibacter sp. AK015|TrEMBL
MNDYRKLLLLVFLWLPFMAVAQVNTGATSFRIVPLGVLGGADESNLSAYMLAPKGSDNYI
CLDAGTIRAGIAKAIAYKTFTIPAEQVLKKDIKGYFISHAHLDHVAGLIMNSPEDSTKNI
YGLQSTLETVKTHYFTWDSWANFADDGVAPQLKKYHYQPLTPGSKMPVENTGMQVQIFPL
SHANLTSTAFLVSSKDNYVLYLGDTGADEIEKSKNLHNLWVAVAPLVKGKKLKAIMIEVS
FPNEQPEKNLFGHLTPHLLMNEMTELGKLSGTSLKGLNVVITHLKPPYKSMLKIKAQLKT
ANKLQLNLIYPKQGIALQL
>A0A0L6CR11|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseovarius tolerans|TrEMBL
MARLLHISDLHAVARGQLVSGRLDTGHLLHEAITTLCARMDAIGPVDAVLVTGDISDDGS
AESYAIAQRELERLGERLLVIPGNHDCRETLRLAFSDLPEIAPRGLIDWVSDIGDTRIVG
LDTLIEGQGGGTLRDESRALLSEALTGAGGLQVVVALHHPPLRTGIRFMDAIGLANPDAL
RDVLDRHDAPVRVLAGHVHGVYHGLLGRHPVVTAPACCSAFAFDRRADAPAGFMTGPTGC
GLIDTAPGGVWTELPFEYDEGPFIF
>A0A1R4KMG7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium esteraromaticum|TrEMBL
MRTAEHREPQRTLLHISDTHLRAGGDRLFDLVDGAETLAHTLTALEGAQIAVDAIVFTGD
LADLGQRGAYAELRRIVDPFAARLDARVVWVMGNHDDRSAFREGLLDDPVGDDSPVDRVD
DISGLRIVTLDSTVPGEHHGEISDSQLAWLEEVLAVPAPLGTILTMHHPPIPSVLPLAAS
VELRDQHRLAPVLRGTDVRAIIAGHLHYSTFATFAGIPVSVASSTCYVQDLTVPAGGSRP
QDGARSVNLVRVHDETVVHAVIGVEQSHILEHIDADEARRRLAVAGIAPRTVVEHLDVPV
LVN
>A0A2P9HP71|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|[Ochrobactrum] soli|TrEMBL
MRIVQITDTHLSPIKTHFNPNWEPLVAWIEQQKPDLIIHTGDLAVDGADIEADLEFCRSC
FEQLSAPVLSVPGNHDIGHLPESHQPVNAERLARWQRHIGPDRWAKDLGDWLIVGLNSLI
IGTGSEQEEDQFQWLENVLENADGKPVAVFAHKPLFVDDPEEGDSGYWGIRPVARQRLYD
LFAQYNVQLHASGHLHRAWKGEAFGTRYVWGPAAAFIVGAMERDLPGERILGAVVHELGE
AATSAIVRIDELTPYVIDDVVHEVYPHHAGDGAKVTEEATQ
>A0A139XZG4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii ARI|TrEMBL
MVRSLIIDLILATDMKNHFETVSRFRVRRNALDFDLSSEEDFWFAVKIIMKCADLSHCSV
PWSQHFQWCQRLSVEFYDQGDEEVARHLPMSPLCDREKHSEVAKSQLGFMSFVAVPLFEE
LMAIDGTGNIEKYCISVMKTNASHWEALSSAAVPVPLLGEAPSPDVAPPLLHLIDGSGAA
AVHPGSKAAEIANRYASSTVTTLDLTCLVYRTQLNRARRSSQHSGRRVSEGTSA
>A0A139XSK3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii ARI|TrEMBL
MHISCVKGRIVARQIDNVFTVIFAIEVLGKFVSYGLEYLQDPIESFDTIVVLTSFTLLVL
GFYVSGIGLLRILRLLSALALLHKYPDSKEKRPELSAGNSSKLEKASSIVEGLLTNVHIP
KYFKTELEWVWDSILANKVYDSHVVENEEEEEDQATETIIAGSDASRKTQAAVRASRAQS
RASKLPHGSSSMVVGTTNGRMSGQILETLREPDPRMMDAALYKSETRNLDPLTATVGGMK
NSPSMFAKGSKSSNMMGSSASKSFRTERNKKAIDIISVLYQASQITGAEQEQVNEAMRPF
DEWQWDALHAGDVCDMNLLPVVFVRAIATFPTIMTKFNFDLDRLFDFLKVVQTSFQKNVK
FHCAAHTADMIQAMHYFLTIGKLGALLSEYDVFLCHFCALVCHFGHPGVTNTFLVKSRHP
RAIRYDDESVNENYVASAISCLVAREEYNFFGDKLPLWQVFRLHMIDILLNFDISKSAHQ
VAMFRTKVSIKFTASTPADKQLLLTILLRAADYSFTCRQLALYSKWKDRMIDEFFAMGDT
EKQLALTVSPFCDRELTNVDKCHVAFAEVAVKPLMTVLVLGLAPHLQKDVLDTLEANQKN
LMQKLDKSD
>W1DQ29|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae IS43|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFID
SSHAGTSKGWLTDETISWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A1Z5JCY6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Fistulifera solaris|TrEMBL
MARFARDILYKFGVLVKQLEEKLGPDTGDLGLRVGLHSGPVTAGVLRGEKSRFQLFGDTV
NTAARMESNGAPNRIHLSKETADLLIQAGKVKWVKPREELIHAKGKGELQTYWLEYSRSE
SRKGSVNSVTDSIRSSLKSEYDESKKILSEISFNPMSEKLQRLVKWNTELLSKSLQLILG
RRAGAQIQVDDDDKMRSLEMASRTVARQGKLVFDEVVEIINLPPKAEISDSDPLQLGVES
IDLSPEVYSQLHDYVRTIAAMYPEDNPFHNFEHASHVCMSTIKLLARIVAPNDDNGAGNL
HDNTYGITSDPLTQFAAVFSALIHDVDHPGVPNMTLVSEGTSLAASYQNKSVAEQNSIDL
AWDLLMDPAYEDLRRALYVNETEFNRFRTLVVNLVMATDIMDKQMGAFRKARWNKVFGEN
DEKDIRGSISQKDINRKATIVLEHLIQASDVSHTMQHWHIFVKWNERLFQEMSLAFDEGR
TDKNPAENWYQGEIGFFDFYIIPLAKKLESCGVFGVSSDEYLQYAQNNRNEWERKGHEQV
QIYVENYRMKREAMTMATPPSLVPQEDEEEEEEES
>A0A0K0DHH4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Angiostrongylus cantonensis|TrEMBL
MKVNDDSLQVLSLLRDAAGQVEGETAQLVKDAVKVLSSHELYAPSITRFRNDRIATQYYD
GLIRLYHPTRHRRRSVVDAFRDKKVALGERRRVSADVKNALENDSDWSFDVLLLEKVTEH
HALSQIGLKIFERWKVADSLGCNEDILERWLCTIESHYHAGNAYHNATHAADVLQATSYF
LDSPSVAAHVSENHAIAALIAATVHDLDHPGRGNAFLINTRQSLAVLYNDHSVLENHHVA
LAFQLTLQQNSNVNIFGNLSREEFTSMRHSIVEMVLATDISRHFEYLVRFNKVKSSFINL
MTLSREREKGLPVTMEVFDRLTCNVPLTQCGFIDMFAREAFANFAELANLAHLCTQLESN
YDQWKSLSTSWIPANNLSLHL
>A0A1S8RCH6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium beijerinckii|TrEMBL
MKNNLRFDSNGKFKIVQFTDIHEGPSRDKSIELMNKILDYENPNMVILSGDIIDGKCQTA
EDVKKAINHIAEPMENRNVPWCIVFGNHDDEHNMMTKEEMMNLYMSFEHNLSQVGHKTFD
RIGNYNLIVESSKDKTPKFNIYMMDSGKYAPAIIGGYDWIKLTQIWWYKRTAINLKKKYK
RLIPALMFFHIPLKKFEKAWKTGLVNGERLEDESCAKINLCLFNKIVKIGDVKGIFVGHD
HFNNYCAALDGVRLGYAGYTGYGGYGDDKIPRGARVFLINEENPADFETWTRREFDTELK
K
>A0A1S8SBI0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium beijerinckii|TrEMBL
MKNDLKFDTNGKFKIVQFTDIHEGPSRDKSINLMNKIIDYEKPNMVILSGDIIDGKCQTA
EDVKKAINHIAEPMENRNVPWCIVFGNHDDEHNMMTKEEMMNLYMSFEHNLSQVGYKTFD
RIGNYNLIVESSKDKTPKFNIYMMDSGKYAPAIIGGYDWIKLTQIRWYKKTAINLKKKYK
RLIPALMFFHIPLKKFKKAWETGLVNGERLEDESCAKINLCLFNKIAKIGDVKGIFVGHD
HFNNYCAVLDGIRLGYAGYTGYGGYGDDKIPRGARVFLINEENPADFKTWTRREFDTELK
K
>A0A1S8S2S5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium beijerinckii|TrEMBL
MCNEISFIHVSDIHFNRYSGDDFDDNDDLRNEMIRDIEKNAKKELRNVKGILVCGDIAFS
GQEAEYDIAEKFLKNILNIFDLSEKDIYCVPGNHDIDQNVPKQSISVYNAQKLIEDQKID
DVDLVLRKFKNDKLIENPLLYPIKEYNKFSNKLSSSFDKMQLYWQSEIKLNSKYNLIIHG
INSAIISNSDDHKYKTKERKMVITQTQIPQNKDGNIYMVLCHHPPECWKDNDILEKLMHE
RVKIQLYGHKHLQKIEVDEKSLKISSGAIHPERDDNWIPCYNWISIKVEKDKLIIKVYPR
ILNDVRVFTCDKKVCESNIYKLVTLDLDLDEDDSLGSNFESEEKDINILNTHDNEYSEQD
LVDSEKEIRKTNITDKEIVYKYLCLNNINKEATLKRCLHSDEIDKNKLDDVDYILQIIKK
NSLEDEFLNILNEYY
>A0A449GTZ5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gordonia paraffinivorans|TrEMBL
MFVVAHISDLHFNGTRFNRNRIQSTLSYVNARAAGIDVLLITGDLADEGTPSEYQEAYGV
LESPLPMLITAGNHDVREPLSSTLLGAETSGPINQARKVGDVLFLVVDSSIPGRNDGHID
DETLAWMSERLAAEDPQTPVFVAFHHPPVDLHMPFMDSIRQTGEERLVPLVETHPNIVAF
LCGHAHTPAVTRFADRPLCVAPGVASTLNLPFEGRDVINRGQPPGIAFHVYDQGRLVTHF
RSVMF
>M4UU43|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ralstonia solanacearum FQY_4|TrEMBL
MHFLQLTDLHIKPPGRLAYRRVDTAAYLSRCVAHILAQPARPDAIVLTGDLVDAGAPDEY
AHLRALLAPLDAAGIRMLPVLGNHDARAAAHEAFADWLAPIPAEARDPQAFQYWTDIGEV
RLIVLDTLDTGAPGGRLGVPRLDWLHDALAAEPARPVVIAMHHPPFATGIGHMDVQSLAA
EDIPAFAQIVRAAGNVERILCGHLHRAIDVRFAGTVASTCPSPAHQVALDLDPEGAPGFV
MEPPAYRVHAWVPGQGLVSHLAYVGTFDGPHPFFEPDGRLID
>A0A3B0WIF4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MPKAALIKQAGAIRFIHITDTHLLNHSEETFHQLNTKESLEAVLSDSRARYPAIDFFLFT
GDISQTGTAESYALFKSVLQEYDLPVYCVPGNHDTPKLLQQVIPDVPGSSINVIAMGEFS
LVLLNSWVDDEHHGIVTQRCLQQLEVHLKNSRSQFNIIAIHHPPVLINSKWLDALGLKNQ
SELLQVIQKHSQNTLLICGHVHQEIDQQIDGLRLLATPSTCHQYEANAEHMSRIATPAPA
YRYVSLSRENNIDTKVHYI
>A0A1W1DZ72|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MGVNTHQNLARVVEKITTVKSDALLISGDLTDNGTLTSYKKLNELLAPIQSDIFVISGNH
DSDNITTVFGDCLFKKISLGAWDIVSVDSVQANKISGFLTENTLIELDAELNNSNAKYIL
IVLHHPIVPMKSTWEDSLSLENPQDLFAILGKHDKIQAVLFGHAHESAEFETQGLKIIAC
PSTAVQFTNEKRIGFNYYTLNDDGHMDYETRWITS
>A0A368F5A9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ancylostoma caninum|TrEMBL
MLERKKQCKSSLLRCKAAVMHLGGFRRDASPPPSYYASGRACAFDSWGLSEYPPSTHNRR
RQARGVQENPRSFQLNDWGPDVFKIDELSKNHALTAITYALFRERGLIKASKSVPSRKSF
QAFEIPSSVFVTYLLNLEHHYRSNPYHNHIHAADVAQSMHVLLTSPVLTEVFSDLEVMAA
IFAGAIHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLCSLS
KKQRLQFRKIVIDMLEGVFLLWKSIWKFLNDYFKRYIIVFPFLRFAPSSVGLHLNAPLDF
LLIFRR
>A0A368GJ69|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ancylostoma caninum|TrEMBL
MHVLLTSPVLTEVFSDLEVMAAIFAGAIHDVDHPGFTNQYLINSNNELAIMYNDERVLEQ
HHLAVAFKLLQDSNCDFLCSLSKKQRL
>A0A811GFK3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acinetobacter bouvetii|TrEMBL
MTLFNNNPDQQDWIIIQISDTHLMNQDDLEFVHMNPEQSFHAVIKQIQQQYPDVDAIINT
GDLAQVPVKETYDRYLSFMHQVGIPFYQIPGNHDNIEIFPFYQNKNQAHAIHFGPWSIVL
LNSAVPNKIDGRIEPEQLQQLDQLLSKYQQQFVVVACHHHPFAMQSKWIDQHKLKNTEDL
TDILAKHSNVKAVICGHVHQDSLNEWHNIQFFSTPSTCVQFKPLSDDFALDDQAPGFRVL
HLKANGQLETQIHRAKTAQQQINREISGY
>A0A3P8KKJ8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Raoultella terrigena|TrEMBL
MIIAQISDIHAGPDNSNLSRFDSALKWLDAVEPDALVLTGDLIDNSWFEGYEAIYSRLNI
QRFPTFILPGNADNKPLMRSVWGERFWSETPFAEGLHFVADMGELRLIGLDTTIQGSSEG
AVGNHLAWLEKSLSYADAAPSMLFLHHHIIQSGIPPMDRIMCKDRAQLGEFLQNSSRQPI
AIATGHVHRPIAGVFSGIPAYICGSICPANPLWFGTEIVPPVNDPPSLMIHRFINHALVS
HTSRFKLSGAREPPLLGSGQRALRG
>A0A0P1F236|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thalassobacter stenotrophicus|TrEMBL
MKFIHLTDTHVIGEGTLYGQDPAARLRAAVASINREHGDADFVVLTGDMTHWGDAAAYER
FSREIEQLNMPAHLMVGNHDDTAAFGAAFPEIPRDENGFVQSSFETQFGRFLLLDTKDPE
SHAGAYCPARQAWLDRELDQTDGSIFLFMHHPPFKIGIAAMDQIMLPDAKTFYDVIAPHK
ARIRHLFFGHVHRAIFGNWRGISHSCMRGLNHQVALDLNGTVDRIRANCEPPAYGVVMLS
DDQVTVHLHAFADRSEQFFL
>A0A2H6G0M6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|bacterium BMS3Abin11|TrEMBL
MRMSVPEGIKFLQISDSHLFENAGKRLIGVNTEASLRAVVGLASKEEDVTGILATGDLSQ
DGSVESYQQFADIVKPLGVPVYWIPGNHDNSYYFHHPENFPLSSRSVINAGNWRILLLDS
VIPGKESGHLSTSELDYIEKHAHDGERHILLVLHHQPIPCGSSWLDTMILNNADDFLQLI
ANKASIRAVLNGHIHQDRRQEIAGVSFISTPSTCFQFKPDTDRFSLDARMPGYRRLILKY
DGGIETEVVRLEDYDLHIEPAVVGY
>A0A517WL72|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia chilikensis|TrEMBL
MSPINPDSRISLGRRAFLQQGALVLGGLTAAPLGQLAAAADQKQRGAVRVGLVTDLHYAD
KPPGGSRHYRETLKKLDEAVTQFKKDEPDFVVFHGDLIDSGKSLEQEKQHLQTIVTAIDA
IPYPRHFVLGNHCVDQLTKAEFLQGVGQKESYFSFDRGGYHFVVLDSCFKSDGTPYGRHN
FKWTDANMPASELKWLKDDLQQTKLPTIVFVHQPLDLKDTDAHAVKNSSEVRKVLESAGN
VAAVFQGHSHRNKYSEIGGIHYCTMVAMVEGSGPTNNGYSTLDVYADGSLVLNGFRKQQD
YHWS
>A0A132C3P5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Tritonibacter horizontis|TrEMBL
MTTSFAPLTVAISDLVKALLEAHGDRINYIHFGHVHAPIHGRFAGIPFASVPSTGNQSLP
DLKETELLKGAPMAPAYFVLSIDGNDTTIHQIPFAWDGPVMTSGTGWEDWAKPGVAAG
>A0A1R4LTJ2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio ruber DSM 16370|TrEMBL
MLIAQLTDLHIKQSGKLAYKKVDTLGCLRHAIHHINRLKPMPDRVIITGDLADFGTPDEY
QLLVAELQRLKPVVRVIPGNHDNRTHLRDALQGWLAFDTPVFCNFSEHVGGYQLIGLDSS
VPGQPYGMLSQATLRWLDEQLSATQHHPALLFMHHPPMTVGLQHMDVQNLQNSDELYQVL
QSHPHVAGIVVGHIHRPIVATWHRIPVWVGPSHSHAVTLDLDPQAPACFSLEPGAIQLFR
LEPEGICSHISYIDAVEGPYPFFDENHCLID
>A0A7H4PHQ6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella michiganensis|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIRASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFTAPCVWLPGNHDFSTGNVQHAAGIRHLSR
>A0A517WQ51|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia aquarii|TrEMBL
MPIHLPTQNRRQFLITLGAGLVASQTGVYATETQEEIVYLLNDTHIGEKHPANSPVPSHL
RQVVSELVGLKRKPACVLINGDLALKDGQPGDYRHFAKLIRPLRDANIETHLTLGNHDQR
DVFYEVMKEEQPESPPVKSRHISVVQTKYANFFLLDSLHKTMVTQGTLGKAQRTWLAKAL
DAHSEKPAIIVTHHNPRLGGNPVHFPGGLTDSAELWELLVARPQVKAYIHGHIHHRGNAQ
HQGIHIFNTPATSYVANPDKSTTGWTIARLSPKGITLTTRTNDEEHAWNHQSKTLHWR
>S7XB47|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Leifsonia rubra CMS 76R|TrEMBL
MTGYESQYPRPEHFLLHLSDTHFLAGERKLYNTLDSEVKLQKLFSELEASGSRPEAIIFT
GDLADKGEPDAYRLLKAIVEPAAERLGAQVVWVMGNHDDRSTFATVMLDEPASEEPIDRV
IDINGLRIITLDSTVPGHHYGHISDAQLLWLHNVLATPAPHGTILAMHHPPVPSMLDLAV
TVELRAQQDLAAVIRGSDIRSIIAGHLHYSTTATFAGIPVSVASATCYTQDLNVAVGGSR
SRDGAQSFNLIHVYDETVLHSVVPLGEYDSLSYVTPEQTAAILAQHNITIAPATNPRVVP
SIVRV
>A0A653P4B0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. 8AS|TrEMBL
MPHPAAPPHDQPVLIVQLSDSHLFAEEGGKLLGMDTCDSLQRVIERVQQEQPHIDLMLAS
GDLSQDGTLGSYQRFRQLTDPLARQARWFAGNHDEMPAMREACAGSDLLDPIIDLGSWRI
TLLDSSIPGAVPGFLGDDQLELLEQSLNAAPERHHLVCFHHHPVSIGCNWMEPIGLRNPQ
ALFAVIERFPQVRAMLWGHVHQEFDQQRDQVRLLASPSTCVQFAPGSEEFQVDRSAPGYR
WLRLHADGLLETGVSRVTGIDFEIDYSVKGY
>A0A6L5CNV6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ephemera danica|TrEMBL
MECSAQCMCAAGYTRRSRASFTLTCSLNSSLWSSCDGNEREYGRLADEDDELSEVQPDAV
PHEVREWLASTFTRQLANQRRRADEKPKFRSVAHAIRAGIFVDRIYRRMSSAPLMQFPPE
VARALKTLDDWTFDVFNLNDAATGAPVKYLGYDLLNRYGIIHKFKVQPQTLENFLSRVEE
GYCRYRNPYHNNLHAADVAQTVHYMLCQTGLMNWLSDLEIFATLVAAVVHDLEHTGTTNN
FHVMAQSDTALLYNDRAVLENHHASATFRLLREEENNILSHLSREEFREFRTLVIDMV
>W6QY62|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas pseudoalcaligenes (strain CECT 5344)|TrEMBL
MPSLPTQSTDSSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIERVLQEQPQIDLILAT
GDLSQDGSEASYQRFRQLTSAIDAPTRWLAGNHDEIPPMQAACQGSELLEPVIDLGAWRI
VMLDSSIPGAVPGFLADGQLELLERALSEAPQRHHLICLHHHPVPIGCKWMEPIGLRNPA
ALFAILDRFPQARALLWGHIHQEFDQMRGNLRLLASPSTCVQFAPGSEEFQVSSEAPGYR
WLRLHADGTLDTGVSRVTGITFEIDYSVKGY
>U6F416|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactobacillus helveticus CIRM-BIA 951|TrEMBL
MEGKLFRKCKKTSQGKDLYYQETALTAFMRMAQRKKPAAIIVTGDITFNGERVSAEKFAE
IFKPLKHTQVLVLPGNHDIFDGWARELRGKKQFYAGEISPMFWRSIFAKSYRQAFNTDDS
SLAYSVQLNPQYFLILADSNIYGTEETTAAPHTRGMIGKSQLKWIEKQLQYAEKINFVRF
YLCIIICMLIILL
>A0A0X8V9V7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Anaerotignum propionicum DSM 1682|TrEMBL
MGLFAIADLHFGFSVNKPMSIFGANWEGHSERIIENWQQEVGKEDTVLIPGDISWAMKEE
DAAADLQVIQGLPGRKIFIEGNHDYWWKSASRLERTFEGMRFLKNDCDLYESLYICGSRG
WLCPNDSRFTAQDQKLYEREQIRLRLSLDSAMRKGAEEILLMMHFPPTNDRQENSAFLEI
IREYPIRQVVYGHLHGKPSHESGIKGERDGIVYHLVSADYLDFCPKRLI
>A0A085G670|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ewingella americana ATCC 33852|TrEMBL
MFLAQISDMHFRSQGRKLYDFIDVNACNAEVVNQLNALEERPDAVVITGDIVNCGLPAEY
LVARRTLQNLHYPLYIIPGNHDDKAQFLEALHPLCPELGHDPQNMRYAVDDFDMRLLFID
SSLAGESKGFLTPETLSWLEEQLKAGGDKPTAVFMHHPPVKVGSAQMDSISCENGDELLA
LIDRFPSLCRVFCGHTHRLIFTQYRQAIITTIPGTVHQVPYYHHNPAPFYNLEPAACVMH
RLVEKTGLVSYLHPLSQYPGPYLYDATISCPVDDE
>A0A1I7Z898|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Steinernema glaseri|TrEMBL
MDRYGSAFLDLDLDPPHIHLTTPWFQIAPEDILRLTVREIPHPTSFHPDFCSFDFFPRSI
GGGDIYVEASLSMFKELGFIETYRLRRRTLARFLLMVQKGYRDVPYHNWSHAFAVSHFCF
MLLKMPAVQHALNELERLSLLVACLCHDIDHRGTTNSFQLQSKTPLAQLYSSEGSVLERH
HFAQTVSILSMEECNIFEQLTRKQYQTVLDHMREIILATDIAAHLRKVHKISAMVEEGYD
RENTDHHYLFMCLLMTASDLSDQTKPFKYAKVIAENIYREFFSQGDLEKQMGNRPIEMMD
REKACVPKMQLEFMDTVAVPVFDMLSRLLPDLRGTYHTMMNTRERWATMKDVVTEEGLPT
GGLEYLRSTHLEEKVERRIEEQRSCAEMVR
>A0A183FPL4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Heligmosomoides polygyrus|TrEMBL
MGLLKKAQTAAMNRISGVRKLRAPSHEGHLPEYGVPCAKEVAVYMQQINDWGPDVFKIDE
LSKNHALTTITYALFRERGLIKIPSSVFVTYLLNLEHHYRSNPYHNHIHAADVAQSMHVL
LTSPVLTEVFSDLEVMAAIFAGAIHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLA
VAFKLLQDSNCDFLCSLSKKQRLQFRKIVIDMVSVLGLLAASDTCGKKLAWSKAV
>A0A0M3J881|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Anisakis simplex|TrEMBL
MEHREICKKAKIDYMTEVKLQNRGLLKTFEIPPGALLTYLLHLEHHYRDNPYHNLVHGGD
VAQSTNVLISCPSLTGVFSELEVLAALFASAVHDVDHPGFTNQYLINSSELLKTK
>A0A0N4V5R6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Enterobius vermicularis|TrEMBL
MDTMCGFRARTVICFPKFCRRHLTVRRSMSLVLHHGLLGTEKLMLKHLFRCFRSVFLCYN
EFFCFHSYSKLLLSLRGQKKVVVFQELGFIEKYHIDKAKLARFILLVSKGYRDVPYHNWS
HAFAVSHFSYLLLRTKSVQEKLTDIERFALLVGSLCHDIDHRGTSNKFQMDLNTRLSRMF
QSKGSIMERHHLNQTQLILKKPEFNILSGLSAEVIKANINDIILATDISVHLKKTDLFEK
MIKDGYNKELLEHRLLFKGLCMTAADLSDQSKDFHNSKSIAANIYCEFFAQGDLEQHVFK
ALPAVSMDRERADLPQVQLDFLDGIGIPTYRHLAMLIPEVQETYEAICFNRKCWAKLGEI
LKRDGLTVRDVDYLSDANLEEQVMNELGGFGISFLA
>A0A0S4VQU4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ralstonia solanacearum|TrEMBL
MVEMTAARGNKTVTVVQITDPHLFADRDSELMGYRTYPMLSKTIDAIRGHDFRPDACFLT
GDISQDESADSYELARFELERLGIPVFWIPGNHDDRGRAEAVFGQSERIHRLSKLTTADW
DFIHLETCRRGADEGYLSDPDFERFVSDVEASAGAGKQIAVVMHHHPVPTQTPLLDGYML
QEGERLLSFLDDQRQVRLVICGHVHGDYQLQYGSQTIEVCPATCFQWEKGTRTAKAEDWR
GFRIFEFSSAGYQSALISV
>B7QI33|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ixodes scapularis|TrEMBL
MVLATEMTKHFEHLSKFLNAFQKPIQEDEAFESEAMPDHGDSGLRSAENIILIKRMLIKC
SDVSNPARPIQLCSQWASRIAEEYCAQTDEEKRRGLPVVMPAFDRATCSIANSQTGFINY
FVRDMFRAWSGKCRLNFPLVSKRLSFCATSL
>A0A2X0PJY7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactobacillus helveticus|TrEMBL
MHHNLYAHNPAVNKGYVVDDAVELRRLCSRYNVKLAFTRHINAQNIMDPQETTPTTEVVT
SSFCSNDQGYGVVRVHSRHITYVRRNFDMTRYLTDQEKENYTLEHFHKYLKDLQLGSISA
DMMQSELNKIHSSQAHQVLIKHHPEYRLYLEILYDTTSHSNLQVKIRY
>A0A2A2HBF3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Methanosphaera cuniculi|TrEMBL
MKILILSDIHSKTDRIYEYLDENSFDDIIITGDVTEFGPEELFVEILDKLSTYAPVYAIK
GNCDPTNADELIEKSSATNVDGKCVNLDKIQLVGFGGSNPTPFDTPNEFSEEIIYDSLNK
FNEQLSDKNKYTILMTHAPAYDTKTDTIESGAHVGSTSVHKIIEQTQPTLNLCGHVHESK
AIDKLENTTLLNPGNAAENNAAILTITDDDIKNKNVNIQLITL
>A8J0R9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chlamydomonas reinhardtii|TrEMBL
MLQVEKVLAGADGWQFDTWRLREVTNGHPLSALGFFLIQRAGLIPRLKLKPAVLARLLRH
IEAGYVDNPYHSATHAADVLQTLHVIIHGAQLHVHYLDPLGLFAAYWAAIVHDYGHPGLT
NDFLIATSDPLAVRYNDRSPLENHHSAASFSALRRPGLDVLAPLSTEQKGAFRKQARVID
MVLATDMKQHFSLLSHFNTRLLSLQIAIKLACLGALSQAADIGHLGESQEVHKRWLSGLE
EEFFRQGDKEKELGIPISPLFDRAKQGVGKSQVGFYDFVALPLVHALAGAFPGTQPL
>L8MLZ6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas furukawaii|TrEMBL
MLLVQLSDSHLFAEADGRLLGMATRDSLRRVVDQVLEEQSCIDLVLATGDLSQDGSAASY
RGFAEEASRIPAPSRWFPGNHDDVPAMREVCAGTSMLEPIVDFPHWRLVLLDSTIEGAVP
GFFPSEQLALLEEAIEGAGERHVLVSFHHHPVSIGCAWMEPIGVRNAEALFAVLDRYPQV
RALLWGHVHQEFDQSRNGVRLLASPSTCVQFAPGSEDFSVGSEAPGYRWLRLTRDGRVET
GVSRVIGIAFEVDYSVKGY
>A0A1B8P5M4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Halomonas elongata|TrEMBL
MRLIQITDCHLHADPAARSRTGVPHRQFVRVVEEAASWRPDMVLVTGDVSQDETAASYAL
AERELARLDCPWSWLPGNHDEPARMAECRPFEESVDLGQRRLLLLDTQVPGQTHGALGRR
VSRHWRNA
>I7KI24|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactobacillus hominis DSM 23910 = CRBIP 24.179|TrEMBL
MITENDAAKFWVISDTHLIADSLHDNGQAFSQMQKTSQGKDLYYQEVVLSAFVKKALDKK
PDAIIVTGDVTFNGERVSAQRFAEIFKPLKGKTKLLILPGNHDIYDGWAREFRGKKQYYA
GQISPLFWKNIFRESYKGALSEDDSSLAYSQQLNSDFLLIMLDSNIYGSEESTTAPATHG
KIGKEQLKWFENQLRLAQEKSLHPIVFMHHNLYAHNPAVNKSYVLDNANEIRRLFGRYGV
KLVFSGHIHAQNILGPQIPTPTSEIVSSSFCSTDQGYGEVHIKKNNLEYRRHSFDMSPYL
SEKEKQNWTLTHFHDYLENIQLGSLAANLMQKDLNKYHNSLDLIRKMGKLFSKMNYNFFT
GKNHISKAQLDKLHASEPYKVLVQENPEVKLYLETLYDISDHDNWNLKIRF
>W8F3W9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Hymenobacter swuensis DY53|TrEMBL
MKKLLLLILSSGCAWAATAQPAFTVIPLGVKGGMTENNLSAYLVAPAGSQSYVCLDAGTV
YNGVEKAVANKVLAGPVGEAVRTNIKAYLISHAHLDHVAGLLLGAPDDAPKSIYGLPGCL
ATIQNDYFNWRSWPNFGPGGTPPALGKYQLWELTPGPEMPLENTSLSVQTFVLSHGRPFQ
SAAFLMRSGLSYLLYLGDTGADAVEQTDNLRTLWQMVAPLVKAGQLKAICIEASYANAQP
EKQLFGHLTPALLMREMAVLSQLAGPGAVRGLPVVVTHIKPTAGNEEAIRRQLQEANTLQ
LRLVFPEQGQRLDF
>A0A2G8YCT4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii COUG|TrEMBL
MHISCVKGRIVARQIDNVFTVIFAIEVLGKFVSYGLEYLQDPIESFDTIVVLTSFTLLVL
GFYVSGIGLLRILRLLSALALLHKYPDSKEKRPELSAGNSSKLEKASSIVEGLLTNVHIP
KYFKTELEWVWDSILANKVYDSHVVENEEEEEDQATETIIAGSDASRKTQAAVRASRAQS
RASKLPHGSSSMVVGTTNGRISGQILETLREPDPRMMDAALYKSETRNLDPLTATVGGMK
NSPSMFAKGSKSSNMMGSSASKSFRTERNKKAIDIISVLYQASQITGAEQEQVNEAMRPF
DEWQWDALHAGDVCDMNLLPVVFVRAIATFPTIMTKFNFDLDRLFDFLKVVQTSFQKNVK
FHCAAHTADMIQAMHYFLTIGKLGALLSEYDVFLCHFCALVCHFGHPGVTNTFLVKSRHP
RAIRYDDESVNENYVASAISCLVAREEYNFFGDKLPLWQVFRLHMIDILLNFDISKSAHQ
VAMFRTKVSIKFTASTPADKQLLLTILLRAADYSFTCRQLALYSKWKDRMIDEFFAMGDT
EKQLALTVSPFCDRELTNVDKCHVAFAEVAVKPLMTVLVLGLAPHLQKDVLDTLEANQKN
LMQKLDKSD
>A3RZM6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ralstonia solanacearum (strain UW551)|TrEMBL
MHFLQLTDLHIKQPGRLAYRRVDTAAYLSRCVAHILAQPVRPDAIVLTGDLVDAGAPEEY
AHLRALLAPLDAAGIRMLPVLGNHDAREAAHAAFADWLAPVPDGARDPHAFQYWTDLGEV
RLIVLDTLDTGFPGGRLGAQRLDWLHGALAAATARPVVIAMHHPPFATGIGHMDVQSLAA
DDLPAFARIVRTAGNVERILCGHLHRSIDVRFAGTVASTCPSPAHQVALDLDPDGEPGFV
MEPPAYKVHAWVPGQGLVSHLAYVGTFDGPHPFFEPDGRLID
>A0A090SA54|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio variabilis|TrEMBL
MLSEIFPTFELDENGFGQKVIETQKGVFILLDTMLEGTHAGVYCEQRLDWLENEISKADA
ANRPVYLFMHHAPFDTGIPALDVIGLEKQASVRLADIFDEFDNIKHLFFGHYHRPIAGSW
RGVAFSTLRSMNHQVRLDMHCENMIQGCFEEPQYCVALLQDDATVVHYHDYMHSSEHFDI
GDPLKAHV
>A0A3P6TYD6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Litomosoides sigmodontis|TrEMBL
MLSFFQLDEWGPDIFKIHEFSNGHSLTCITFTILKKRGLLKTFEIPSGILLNYLLHLEHH
YRDNPYHNQVHAADVTQSVNVLISSPTLQDVFSELEVLASIFAGAIHDVDHPGFTNHYLI
NTNSELAIMYNDESVLEQHHLAVAFKLLQDSNSILKFEYVQYFNKKRYRILHVLATDMSK
HMSILADLKTMVEAKKVAGSSVLTLDKTDGLQVMQTMIHLADLSNPTKPISIYSIWVKNI
MEEYWRQGDRERDLGIDISPMCDRNNITIAKSQVGFIDFIVQPLFETWADLVNPHAQYIL
DQLELNRQWYQARIPEEQDKHDATEEKTSANVESMTNSLK
>A0A086PLZ6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii MAS|TrEMBL
MTVIELIMSTDMKTHFEQIANFRVRRQKEEFDPINNYDDRQKVMSMIIKSADIGHGTLPW
ADHERWCDLVVQEFYEQGDEEKRLGLPVSFLCDRDQHDREFFKSQVGFLDFVVKPLYEEL
KALETQLNLNPQLPIENICMKNLQENISEWKKKNEERRASLEPAGLEVGGA
>A0A090TVT1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio maritimus|TrEMBL
MKIIHLTDTHFGYTGQKIYQRSPQHALTKAVESINREHSDAEMVVITGDLAHAGHPEAYT
NLQSTLSKLDIPYHLVIGNHDHRPTLAETFGNFEFDENGFAQKVIQTERGVFILLDTVKE
GTHAGTYCEQRFQWLKQQIDSANGQPVYLFMHHAPFDTGIPAMDAISLDKAHGEQLGNLL
DQYSNIKHLFFGHYHRPIAGQWRGIAFSTLRSMNHQVRLDLNDEKMIQGNFEEPQYCVVL
LENDRTLIHYHDYMHESEEFEIGSPFVAHI
>A0A086QXD3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii MAS|TrEMBL
MTEWPSMRCAATATTPLRSRLTSVSLFAARHPRFNVFCSIPPQAFSACRQRIISAILWTD
MAKHFDMVAQLKAKIEDEMVLTEGIIITLQKPYLEGLLLHASDISNPLLSFDLSFDWAVR
ACDEFFQQNRLEEKLGQPPHMPTFAAFDLYNVAKCQVNFIGEFPPWFTGHPLSHLPPETN
EFLCMHTHSKMQIHREKNVDTEAMTENTNPSPNSHA
>A0A5C5WIU5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rubripirellula amarantea|TrEMBL
MSLHLPGSRRSFLQTAVGVGAIAIAGRSSVALDSQSDESYVFFSDTHICGDKTKIVSDAN
MFANLSRAIDEVLALPQLPRALFVNGDCAYLKGLAEDYATFASEIRRVSQAGIDLHMTMG
NHDDRGPFANALSEHARQSPVQGKHVSIIEGQHVNWFLIDSLQIVDNVTGEIGNAQRKWL
AEALDRHSDKPAIVMGHHNPQYLPEGSSERVTGLVDTAELVDVFHAHANVKAYIYGHTHH
WKMTETAGKVHLVNLPPTAYVFNKTMPNGWVHAKVDGSSLSMTMHAFDDQHPTHLGEHRL
AFR
>A0A128FEL0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Grimontia marina|TrEMBL
MVDEIRASHVEFDAIIATGDISQDHTAESYQRFVDGIAHWSEPCFWLPGNHDYQQEMQSI
LAQSSLQRCDSVLVGEHWQLVVLDSQVKGVPHGRLSKEQLSLLVTALSTNKDRHTLVLLH
HHPLPAGSAWLDQHQLHNQEDFWTVVEKHNNVKGVVCGHIHQALDTEYKGRRVMAAPSTC
IQFKPDSDDFALDCTNPGWREIELHQDGTIITHVGRLKGTEFQPDMNSSGY
>A0A083ZXZ2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serratia sp. DD3|TrEMBL
MTKIIHITDTHLVEANHLLYGLDPNQRLGRCIDSILQEHADADLCVVTGDLTHAGHPQAY
QQLAQQLSRLPMPVHPIIGNHDQRDLFREHFPHTPTDAHGFIQYRVDIGGFNALFLDTHA
PGVSYGVFCEQRSQWLAEQLTRDPRPALLFMHHPPFAVGIPSMDNISLLDTVPFTSAIQP
HLDRIRHIFFGHLHRPISGSWRGISFSTLRGTNHQVALDLRAQGKVPGSHEPAQYGVVLL
SEEQITVHLHDFEDNSPRFWL
>A0A4W6DPN8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lates calcarifer|TrEMBL
MLNLLCVVCFLLLDLHDAKHHSHIQYTGVLEQMDRGVVDLQELRRNLELAAAMLDAVYTD
ETRRLLDTEDELSDLQAESVPSEVRDWLACTFSRKMGVAKRRPEEKPRFRSIVHAVQAGI
FVERMYRRTSNMAGLTYPPTALTEVDQWSFDVFSFHEATGDHALKFLVYDLLTRYDLINR
FRIPVQALVQFVEALENGYSKHRNPYHNLIHAADVTQTAHFLMLHTGLMHWLSELEILAM
VFAAAIHDFEHTGTTNNFHIHTRSEVAILYNDRSVLENHHVSAAYRLMAEEDMNILVNLN
KDDWRELRSLVIEMVMSTDMSCHFQQIKTMRNALTQTHGIDKVKVLSLMLHAADISHPAK
AWPLHYRWTHSLMEEFFRQVLCCSGIHEAVFRAFSENPKI
>A0A238H824|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Burkholderia singularis|TrEMBL
MLLAHISDLHIKRPGALAYRRVDTAAHFTRCVARLNALTPRPDAVLITGDLTDFGTDDEY
AHLKSLLAPLEMPYYLLVGNHDDRAALRRAFVERAELHTGGEFVQYTIDAGPLRVIALDS
QMPGTSGGTLCDARLAWLEAELDAARARPVVVALHHPPFVSGIEHMDAMRLAPPDAGRLD
ALLRRHPNVERVLCGHVHRAMFARFGGTIASAVPAPAHQVTFDLGRDGPSSFTMEPPAFA
VHRYAPATGMTSHHVYVDASDGPYPFFDPAGGLID
>T0ZZC0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|mine drainage metagenome|TrEMBL
MRKEGNLELVTIYEISKVLGSSLNLQKTLREVLNLLASHLRMDRCMVALLQEDNILHVIG
ASGMTETEVKRGFFRIGEGVMGKVVKSGMTIVVPDISKEPNFLHKTGPRTIQEGEVISFI
GVPIKVGRESIGVLGVDRHLNGEPQNFRE
>A0A2K4X168|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas syringae|TrEMBL
MPSAAPSSSVLLVQISDSHLFAEADGALLGMSTRDSLEKVVDLVLAEQPQVDLVVASGDI
SQDGSVESYEAFRRISTQIAAPARWFAGNHDELPQMEQVAQAEGLLEPIINIGRWRVTLL
DSAVPGSVPGFLAAGQLQLLEQSLSEAPDRHHLVCLHHHPVAIGCEWMAPIGLRNADALF
AVLDRFPQVRAVLWGHVHQEFDQMRNGVRLLASPSTCIQFAPGSADFKVDTTAPGYRWLR
LHDDGRLETAVSRVVGMEFEVDYGGTGY
>A0A378XTK3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oligella urethralis|TrEMBL
MTIIAQITDLHIREPGRLAYKRINTAPYLERAVNTLMTQKQKVDALIVTGDLCDFGRESE
YDHLKRLLQPLDCPVYLMPGNHDNREQLRRSFDTHTYLQQHHGEQIYYSVKIGVVQLIAL
DTAVLGKSYGELDKTQLQWLDRQLSQSRGAPVIIAMHHPPFNTLIGHMDKIGLLKGATEL
AEIVKKYPNVERVICGHLHRSIDVRFAGTIASTAPSVAHQVALDIDPNAASCWVLEPSAY
KLHIWQGDGPLVSHLAYVDNYEGPYPFYENGQLID
>A0A482ZDT4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured SUP05 cluster bacterium|TrEMBL
MKRLLQISDCHIDDVEQSIGVNSHQNLSLVVDKITQLEADALLISGDLSHYGSLNSYKKL
KQLLAPIDTDLFVIAGNHDDKNNLSAVFNENLFTLFTLGKWDIISVDSVQAGQTSGYLTK
QVLLDLEARLTQSTAEYILLVLHHPIVSMQSTWDDTLSLENPQDLFAILTKHSNIQAVLF
GHAHQSAEFKKNGLRIIACPSTAVQFNDESRIGFNYYRLYDEGKFDCEVKWIAS
>A0A091MM59|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acanthisitta chloris|TrEMBL
RLRCLVKQLEKGDINVVDLKKNIEYAASVLEAVYIDETRKLLDTEDELSDIQSDSVPLEV
RDWLASTFTREMGIVKRRPEEKPKFRSIVHAVQAGIFVERMYRRTSSMVGLAYPAEVIVT
FKDVDKWSFDVFALNEASGEHSLKFMMYELFTRYELLNRFKIPVPNLISFAEALEVGYSK
YKNPYHNLIHAADVTQTVHYIMIHTGIMHWLTELEILAMIFAAAVHDYEHTGTTNNFHIQ
TRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILANLNKDDWR
>A0A8M1NSS2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Danio rerio|TrEMBL
MELCYQLPVLPLDRPVPKHVLSRRGAISFSSSSSLFGAPDPRQLSQRRGAISYDSSDQTA
LYIRMLGDVRVRSQVGFEPERRGSHPYLGIDFRTLHSRAESAGSIPARRIRRLFSFQRHL
LSSRLLRGAPHLNPLHILDEDYCGQAKCMLEKVGSWNFDIFLFDRLTNGNSLVFLTFHLL
SQYGLIELFQLDMVKVRRFLVLVQEDYHNQNPYHNAVHAADVTQAMHCYLREPKLAQSLT
SFDILLGLLAAATHDLDHPGVNQPFLIKTNHYLAALYRNTSVLENHHWRSAVGLLRETEL
FSHLPAEDSLSIERQLGSLILATDISRQNEYLSRFRTHLDENDLNLGNASHRHFVLQMAL
KCADICNPCRPWELSKQWSEKVTEEFFHQGDIEKKLKLEISPLCDSEANTIASVQIGFMT
YVVEPLFAEWARFSDTRLSQTMLGHLGLNKASWSTMEPEASGSSEDGESDPARSSEEPSS
RALTQGSPES
>A0A1V5BKJ4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pelotomaculum sp. PtaU1.Bin035|TrEMBL
MLSGTIIKNEELCTVSSNHAVITWVTPKQRANTTICIGEDSLNLVKHTFGSNTEFHWAEV
FNLKPSTRYWYQAECNGAHGSLNSFTTLPRPEGKYLFSFALLSDTHISYGESTDDINEKY
FGKLVEYSGDLLIQCIADSKKRNIDLAVITGDLTDSARQPQYLGLRNQLLPCFGNTPYFL
CIGNHDCYVNDSGMGKQGFLSYVANRENTHANIMFRDYQFLLIDSCRQNDNWGHIDSTQL
QWIESILKKGRGNPSFLFLHHPCNGLDTWFGTKNYRDLQKVIKCFPGVQSVFSGHIHRNK
ITTNQLTTGNLPYVEVAATVQFPCSYAIVRVYENGFEYNSYKVSRLDLAEMSRERFILKH
RGRDIYTWYSFGGIGDRSFSYFNGRLYRPEQYELSVIADQTRAVRLYEHAQSFNGASMAP
AETGKYKVILGRHELLHLAAQARRQIFSRYSVNARVIREGK
>A0A2U1S796|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Methanobrevibacter woesei|TrEMBL
MKFLAISDIHGEENENLYRYVKENDIDLVLVAGDITDFGPLEFVGQFMDNLFDCDCDVVA
IPGNCDPSGICNSITESGALCLHNNIIAYGDAVIFGYGGSNPTPFDTPGEIQDNKIYGDV
YELLAEYDYLANDKVPKVRILLTHAPPFNTDADLTDGGDHVGSQGIQKSIHEFKPEISIC
GHIHEAKSISKLGDNTIVANPGMLKDNGAILINIENGKNYSVDIIDLSS
>A0A161MDR0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Triatoma infestans|TrEMBL
TALLYNDRAVLENHHISASFRILKDEECNVLQNLSREEYREFRSLVIDMVLATDMSFHFQ
QLKNMKNLLSLAEPSVDKSKALSLVLHCCDISHPAKRWDLHHKWTTRLLEEFFRQGDKER
NLGLPFSPLCDRNNIMIAESQIGFIDFIVDPSMAVCSDMLETILAPINTTNNPGSDSKKN
NVLGSENPESERPFSVEKPWVPCLAENKKIWKEKAVHEAAQSAEQKNNEPTEETVEE
>U4QA04|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactobacillus helveticus CIRM-BIA 953|TrEMBL
MITEDLNTEFWVISDTHLIAKSLHDEGQAFSQMQKTSQGKDLYYQETALTAFMRMAQRKK
PAAIIVTGDITFNGERVSAEKFAEIFKPLKHTQVLVLPGNHDIFDGWAREFRGKKQFYAG
EISPMFWRSIFAKSYRQAFNTDDSSLAYSVQLNPQYFLILADSNIYGTEETTAAPHTRGM
IGKSQLKWIEKQLQYAEKNQLRPILFMHHNLYAHNPAVNKGYVVDDAVELRRLCSRYNVK
LAFTRHINAQNIMGPQETTPTTEVVTSSFCSNDQGYGVVRVHSRHITYVRRNFNMTRYLT
DQEKENYTLEHFHKYLKDLQLGSISADMMQSELNKIHSSQAYQVLIKHHPEYRLYLETLY
DTTSHSNLQVKIRY
>A0A3R7YKF5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii CAST|TrEMBL
MEERRLLKGNSQTPLKASDTQSTENELPLPKNLGGSSVHGRQSATTDAATHAPSIASVNS
KAASAEPSQCSPSGDAPSELKSILVNRQLKPRDADEDADTGKGPCFGPTQSQFFGTGHSQ
YSCWERFTDFMMPLWENEVNFVLKEECDKQAFADRDPRPIRSKPKFLSQ
>A0A518IK20|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia fumaroli|TrEMBL
MANLTFLQNEPLGRRAFLKNGTLFLAGVSSPALGMLSARAEETKQRGTVRVGLVTDLHYA
DKPPAGSRHYRETIAKLKEVVGQFQSDRPDFVVFHGDLIDSGESLEQEKVHLQTVVKAIS
AMPFPKHYVLGNHCVDQLKKVEFLQGVGQKASYYSFDKNGFHFVVLDSCFKSDGTPYGRR
NFKWTDANVPPPELEWLQTDLKQTTHPTIIFAHQPLDLKDTDAHAVKNSSEVRKVLEQSG
KVAAVFQGHSHRNHYSEIGGIHYCTMVAMVEGAGLSNNGYSTLDLLEDGSLVLNGFRKQD
DYHWKKS
>A0A518IJ72|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia fumaroli|TrEMBL
MPVHLPAQNRRQFLFTLGAGFITYSTSAFASETQSEDLVYLLNDTHIGEKHPTNSPVPSH
LRQAVSELVNLEQKPACVLINGDLALKDGQPGDYRHFAKLIRPLREAKIDTHLTLGNHDE
RDVFYGVMEEEKPATPPVKSKHISVVQTKHANFFLLDSLHKTMVTQGTLGKEQRAWLTNA
LDAHADKPAIIVTHHNPRLGGDPNHFPGGLTDSVELWEILAPRKQVKAYIHGHIHDRGNA
QHKGIHILNTPATSYVANPKLSTTGWTVAKLSPNGVTLTTHTTDPKHSWNQQAKTLTWR
>A0A379LV28|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodococcus gordoniae|TrEMBL
MESIEVDGVFNVRSVSGPYLAPGRLFRSATLDHLTDEGRKVLEQIGIRTVIDLRDNRERP
GSTATASWNVLHHPLYDPATGPPRSGEITAIYRTLLDERGTALTDAVRTLAYSPAPALVH
CTAGKDRTGLVVAVAAAAVGVPDSAILDDYSCSGPRLRPYRENAVRILLSDLTLDPAQYA
ESVELHLDSPAPALQSALDHIRRRHGSVTGYLDAHGFTADDLAALRTRLLGEPELTVLHL
SDVHARGTEDPSGRGTEEFFFGVDGVGRLRAVIEGASTSRLRPDIVVVTGDLAHRRAAST
YPRLAAVFDEIRTRLQCPVLTVPGNHDDPVAFASVFGTNPEEHLRGFRVLGVDTSPGSLS
SDELERLSHELATPAPYGTVVVMHHPPVPSPAATLTGRELARADEFAAVLHGSDVTAILA
GHFHHPMAGVFAGVPVWVGGSLAYLQDIGTPGDSLVAFDDPAYSLVQCSRSGVRALPVAL
RTPEVLFRSSPTLTVAS
>A0A0C2HGF1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ancylostoma duodenale|TrEMBL
MDTVIIKVMNFAAKLVDADRASLFLVDNKNHELYARIFDVGKGGEEFEKISKEGHKEIRF
SMNRGIAGHVASTGEGLNIEDAYEDSRFNPEVDSKTGYTTKTILCMPIFIRGSVIGVVQM
VNKHEGVFTKADEDSFEVFAVYCGLALHHAKLYDKIRRSEQKYRVALEVLAYHSVCNKDE
VAKLQKMEIKERVEELETFEFNYLRMSELEKPLYAISMFKTLFQDQFRYDRDDLIRFVLT
VRKNYRRVAYHNWAHGWSVAHAMFVLLMHTSRDIFNTHEALALYVSCLCHDLDHRGKNNA
YMKSMMTPLASIYTTSVMEHHHFNQTVTILQQDKVHRNNRTIR
>A0A517RNC0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia alba|TrEMBL
MANLIFLQNEPLGRRAFLKNGTLFLAGVSSPALGMLSARAAESKQRGTVRIGLVTDLHYA
DKPPAGSRHYRETITKLKEVVGQFQSDQPDFVVFHGDLIDSGESLEQEKVHLQTVVKAIS
AMPFPKHYVLGNHCVDQLKKVEFLQGVGQKASYYSFDKNGFHFVVLDSCFKSDGTPYGRR
NFKWTDANVPPPELEWLQADLKQTTHPTIIFAHQPLDLKDTDAHAVKNSSEVRKVLEQSG
KVAAVFQGHSHRNHYSEIGGIHYCTMVAMVEGSGLSNNGYSTLDLLEDGSLVLNGFRKQD
DYHWKKS
>A0A6J8AKW4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mytilus coruscus|TrEMBL
MSNHNVFIIVSAIVVAVQSSSDIKTYRINAKVPGGSINEDIVVDSDKHLMTVNVGNVYHL
QSDCPSTINLHDFEKGKLAMKNIDTGKCLVMDTKENLNATIDLLEKITRLKMTHEIKAEK
LVDVYPTTYDRLLEEAGEHIIEFCKGYELLYGEIIDYQEGVKRRDKRKAKKKGGTKLICI
VKLFNHSAVKTLC
>A0A378QI96|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moraxella lacunata|TrEMBL
MTYPTHLSAPSDFIIAQISDLHLSMHAPTNTDKFLKVLDFALIFEPNLLLLTGDLVNDGN
TDLYDWLFDKLDKTNIPYLCLAGNHDVTHEIGHDLPFDKRTFLPITKDNRLIDTHRLVIE
LPHTTWQLLAVNSAVGGHIYGRLDDDKLAFLKTHLSHAMPTLIALHHHPTPVGSAWIDEH
MLQNGDEFWATLNAHATDTANRPHVLCGHVHQAHILQQNGGTLYTCPATSRQFAPYRDEF
GIDGVASGFRLLQLHNNRTLDTWVKRLDNSGF
>A0A166A9M7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Methanobrevibacter filiformis|TrEMBL
MKILQVSDVHSEDNSKFNRYLDENDIDLLIISGDITNFGPPEFAINFLNNIFLKEIPIIA
IPGNCDNPESIEAIKRSNAIFAHNKVIFFKGIIIYSFGGSNPTPFNTPFEFSEEELYDNL
KNLFNKSPLILDENDKRSFIEDNLRVLLTHAPPIDSEADKIENGAHVGSSSVNKIIKEFN
PNLNLCGHIHEAESISKINDTIVVNPGMLKNNKGILIDINGLDIKVNIIEFN
>A0A518J247|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rosistilla oblonga|TrEMBL
MPIHKIPQSRRRFLQTTVVGGGAALLMSSTQRLSAAEADATVIALLSDTHIPSSHDVEAR
GINMTDNLQRVIGEVVARKTRPTDLIINGDCAYLKGLPGDYQNLVSCLAPLDRAGISLHL
TMGNHDDRQPLYDALSDQRPADAQVTAKHVSVIETPHANFFLLDSLFRVNVVTGEIGAAQ
IQWLAKQLDARADKPAIVMTHHTPQFTAPAEGKPWTGISDTAALMAVLDSRKHVKAYLYG
HSHHWNHSQRGHFQMINLPPVAYVFNDKSPNGWVEAVLTPGEMRLELQTLDPKHPLSGEV
VTVALNRV
>I7LAL1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactobacillus pasteurii DSM 23907 = CRBIP 24.76|TrEMBL
MIDKKLTSTDKPKIWVISDTHLISQDLYLDGPAFQKMRDTAAGKDLDHQEYALTALVRKA
IVDKPDAIVITGDLTFNGELKSAERLAEIFQPLTEHGITLLPVPGNHDINDGWAREFSQE
RQYLTKQISPEDWKRIFSASYDKAYHEDDSSLSYSVLLNDNYRLILMDSCIYGEQASTSA
PNTNGRLSEAEFAWLEDELLDAQRQNQRVVYFMHHNLYAHHKMVYRGFVLDNADRLQELF
AKYQVKLAFTGHIHAQNIAGPMNDCPAVDIATGAYSVAETNYGEAIFSNEGIDYQYQTLE
ITDYLTDSEKKSLGIDNFNKYLTQVFRETDNAQNSTKRFDQADVPAVHEFMFKMNYNYFV
GMSLYNREEKENLATSRPYQLLVKNLPGMKNYFAEFWQIKQDSRKLHIRY
>A0A448I4L4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mycolicibacterium chitae|TrEMBL
MGEVREAEHGRPTHRLVHLSDTHLVGAGRLYGQLDAEARLQQILEEMLASQARVDALIFT
GDLADRGERQAYTRLHELVAPVATELGAQVIWVMGNHDDRANFRAEFLPAAPGTGAVDYV
YDLDGLRVVTLDTTVPGHHHGEIDEQRLQWLAAQLATPAPHGTILAMHHPPIPCVQDLAV
LVELREQTRLARVLRGTDVRAILAGHLHYSTSATFAGIPVSVVAATCYTQDLNAPVGAQR
GRDGAQSSNLVHVYPDTIVHSVVPIGTYATVGEAVSADETARRLREAGIRIPGAPLLPT
>A0A0K0DKC6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Angiostrongylus cantonensis|TrEMBL
MLRRKLGHVGFRHGDDLIVTPFAQLLASLRNVRSNLISIANIQTSDDGRHANRMAKRPPL
HSTPLPENVVACAQETLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAESSK
SGTQVSKFLITTYMDKDEDDPSVEVEMPGEGPSTSSSHLSMGLLKKAQTAAMNRISGVKK
LRAPSHEGHLPEYGVHCAKEVSVYMQQLNEWGPDVFKIDELSKNHALTAITYALFRERGL
IKAFEIPSSIFVTYLLNLEHHYRANPYHNHIHAADVAQSMYVLLTSPVLTEVFSDLEVMA
AIFAGAIHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLCTL
SKKQRLQFRKIVIDMVSIFRSSPHDFSLITAVTSKI
>J9EPN6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Wuchereria bancrofti|TrEMBL
MLDNSYGFHNLAIRKHACRLRYVLHQLNGGQLSMDDLKKNLEYMALLLETECMNETRRIC
DEEDDLADVKPEAVSDEVRKWLAATFTKQSVLSKREKPKLKSVANAILTGIFFDKMFRKS
QVLLISTPPEIAALMKNVNSWSFDCFRLNEVSEGHALKYVGLELFNRYRFLDRYKIPVQI
LENYIGALEVGYSKHNNPYHNVVHAADVTASSHFMLSQTGFATSLSDLDILAVIFGAMIH
DYQHTGHTNNFHIQTG
>U2EPG4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salinisphaera shabanensis E1L3A|TrEMBL
MRITLQIIHLTDLHLRADADARLHGWLVEDAFQRVLAAALEALPRPDAIVLGGDLVDDES
VRGYKRLDSTLARLPCPVLAMAGNHDDPLRMAQTLEHAVVHERLRVGEWQLMALDSHING
SEAGELGGQQLERLDGWLAENTAPTLIFVHHPPIDVGAAWIDAIGLHDRDALERVVAGRA
HVKAVLCGHAHQAAELDFADRPCLVTPSTMRQFAPGAHSFTDDPARAPGYRLIEIAADQS
FETTVKRVRSATAACG
>A0A3B0SWZ1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MLMAQVTDIHLGFDPDNPAEFNRKRLDQALKYICEMTPQPDMLLATGDLVDRGDQASYQR
LENALSDVPFPAYMCLGNHDLRAPFHKQFPDVPMVDGFVQYEVDDGPLRLLFLDTLKEGR
HGGSFCETRARWLSDRLAEKPDKPTILILHHPPVESGIAWMNTHPDEPWVSRLADAMAGH
GQVKAMITGHLHRNVSTFFEGKSLSICASTAPQVAFDLALIDPEKPDGRNMIVADPPAIA
LHWWNGQQLVSHFETAEEHVMLARYDENLQPLVKALLAERPK
>A0A446A4M1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. JV551A1|TrEMBL
MPQQDQSRPVHVVQLTDAHLFADPAGSMLGLNTRDSLRHVVAQVRREQPLVDLLLCTGDL
SQDASAASYEAFRELTAPFAVPTRWLPGNHDEARVMAQVAPELVQAVTDIGAWRIITLDT
AVPGATHGLLEDDQLSVLKAALQEAGNRHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDI
VEGYPQVRALLWGHVHQEWDEMRGGRRLLATPSTCIQFAAGSEDFKVSEEQPGYRWLRLH
ADGRLETGVERALDFEVKLDFDSPGY
>A0A377INX8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Glaesserella parasuis|TrEMBL
MDDSYIFPLSSPIIRILQITDSHLFASDTCELLGVNTTQSFQAVLNMIMKESFEYDLILA
TGDLVQDHNREAYHRFAKMVKPLVKPLFWVAGNHDLQPQMRNALSIYSQIKPEKHILVGD
HWQIILLDSHIQDSPKGRLEFSELAFLKKKVGSPS
>A0A0P1F1A9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thalassobacter stenotrophicus|TrEMBL
MHKILVLTDLHITPPGELIIGLDPAERLSRVLDAMRAAHADADHLLILGDLVHYGTAEEY
ARLRGLLRDLPWPTTFMMGNHDDRDTFCATFPRAGLDANGFVQSRITLPHAHILCLDTLA
PDAKPRHSGFLCADRMDWLRTELARAPGTPKIVALHHPPFVTGFDGMDRIGLVNRAEVIE
TLQACADVRLVIAGHIHRTIMASAGGLPMAVFKSPCHQMPLQLGAGTSGLSIDESGAYGL
LLVGPDGDICVHTEDVAAHKAAILDDIASK
>A0A4X3PFN6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pristionchus pacificus|TrEMBL
MAAEFSVNPEEIRRLSSLPIPPTSHFSPHFTSFHFIPRSIGGGDAYVEASIAIFNELGFI
NRYRIERKKLAGFVLRVAQGYRNVPYHNWSHAFAVAHFAFLLLRTPAVRGQLDELERLSL
VIACLCHDIDHRGTTNSFQKQARTPLAQLYSSEGSVLERHHYQQTTNILSEVECDILCNL
TGNQHKTVYDHIKEIILATDIAQHMTKVGEMRKMITQGINPSREQHHYLMVCLLMTASDL
SDQTKHFKNSKGIAESIYTEFFSQGDLEKQMGAAPVEMMDRDRACVPRVQIDFIDTVALP
VFDMLSSAVPESLPTFHSLLNNRRCWAYLEEIFKERGVTTNGLDFLTDQLLEDEVLSRAR
SHNCRSDIDEVLQSIDWTPLNPSKLDHL
>A0A166CU43|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Methanobrevibacter cuticularis|TrEMBL
MKILAITDVHSENNPKFDNYIKNNDLDLVIVAGDITNFGPPEFATEFLNNITSLGIEVIA
IPGNCDTKESILAIEESDAIFNHNNLFINQNIAFHGFGGSNPTPFDTPFEFDDEELYENI
NDLFNQVVSNQRMLNILITHAPPLNCEADKLEDGSHVGSNGVRKIIEEHQPDISICGHIH
EARSIDKIDETLVINPGMLKDNHGSLIEISKDLSDFKVDLVEF
>A0A518LDC3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Planctomycetes bacterium TBK1r|TrEMBL
MNHRINRRQFQAIAASSTLAFSTAANAQPAPQPAPQMAFLSDTHVDADTNTVARGIRMAE
HLEQVVGQVVDALPSGSHVIVNGDCAYLKGLPGDYATFAKLVAPLNNAGLQLHVTMGNHD
DRGPLYQALSDQQSNDVAVEDKHVDVIRLGQTDVVLLDSLWKVNQVTGEIGAAQLQWLKE
FLAADTQRPVVVVSHHNLQFSPPAGGKAYSGVKDTVAFTTLLQQHPRVKAYFYGHTHRWE
NRVLDGDAAQLHLVNLPAVAYVFDVKQPSGWVQGTFSDSELRLRINTLDRSHPNSDEELR
VSLKV
>A0A127N1A8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas citronellolis|TrEMBL
MPAKEFSSNEPVLLVQLTDSHLFAEHDGRLLGMDTADSLQQVVKRVLEEQPQIDLVLATG
DISQDGSPESYRRFLDICSSIQAPARWFPGNHDELAPMREVCAGSDLLDPVLDLGAWRIV
LLDSTIPGAVPGQVSAEQLALLDQALHDARDRHVLVAFHHHPVSIGSQWMDRIGIRNPDD
LFAVLDRHRHVRCLLWGHVHQEIDRLRGDVRLLASPSTCVQFAPGSEDFGVDSLAPGYRW
LRLLPDGGVQTGVSRVTGIDFQVDYSVQGY
>A0A8C6L5A9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nothobranchius furzeri|TrEMBL
RGMIKINKPLNKPKFRSIVHAVQAGIFVERCANVYVGLYSSYQPAEVVNCLRDVDRWNFD
VFALNSASSDHALRTLVFELITRYELNSRFKIPISCMTEFLSALERGYCKHNNPYHNHIH
AADVTQTLHCLLLRSGLVNWLTELEVMASLFAAAIHDFEHTGTTNNFHIHTKSEFALIYN
DRSVQESHHVSAAFRLLQEDQMNIFMNLTREEWMELRSLVIEMVLSTDMSSHLLQVKCMK
AFLQQQERIDKPKALSLLLHTADISHPSKPWALHSRWTKSLMEEFFRQGDREAELGLPFS
PLCDRNSTLIAESQIGFIDFIVYPTFSLLTEMAEKIVIPLVEENPGPLDPCNRHRY
>A0A2A2LJV6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Diploscapter pachys|TrEMBL
MPTQLIFFSAYAFRVVPSSDSPILHSTSHDSCLLYQKVLSAQGRTHMATELVVQGNQFLV
SEDEIRRLLAEPVHEWRFFHSDFAQFSFSPRSIGNSQTYEQAALSMFQDLGFVQRYQITK
RRLVSFVLRVSKGYREVPYHNWSHAFAVAHFCWLCLRTETARRGLDELERFALLIACLCH
DIDHRGTTNSFQLQSKTPLAQLYSSEGSVLERHHYAQTVAILQMESCNILENLTNLQYKT
VLSHIREVILATDIAVHLQKVDRIQNMVNSKLIFAFFQNVIGFLLDGYDSFSSDHHYLFR
CLMITASDLSDQSKDFRNSKAIAVSFTLICKSIVLR
>Q8I533|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Plasmodium falciparum (isolate 3D7)|TrEMBL
MEIKCDINHNLNGKCSLQNFVRNISLDNEKKVLHVFELKNIRTIYDLIFSVSFFKFSNCM
TDVYNNDSGEDISIHKLNINWKGHKNVLCANNKLKQDNELATIVYDKDICNIKNGTIQGK
NSNINDILKSSINTSKNNNNINNNNINNNNINNNNNNNHLYNKDEFINNTLKNEEYNNIL
SNTELNKMNPSNNKEENNTTTLHPKHSNVMEINEMNNYYEKKKKECTYNNEYVYFDIYIN
SDIINIFHVNDKDKEKLIKYIYDIIETNDILIMCIYLNLQNVYEKLEKYNILNITLLKNI
IEANKFEWMKNEIGISLSEFILIINFILKVKKNRIFCSNIFNQYNKNNNKTTKKKKNTKT
LCDKIHQFIEFDNWTFKNIIDNPFFQRLRSLSQLGACQYVYPGATHSRFEHSLGVGFLSA
KYFTHLCNRSNLSPNHGELKRMLRCVQIAGLCHDLGHGPFSHTFESFFMNYKKEDTDHKW
NHASMSLNIAEHIIENLIDKDDVLDVSDIKIIKKLIKGTENNKPFCGIDPIDSLITASFD
IICNNKNGLDADRFDYLQRDATIAPPNGTLPSLNCNRIIGQSAVINGHITYNVKEIHPVW
TVYMNRFSLFKQVYTHRKVRAMELMLCDGFRLADDIFKWSESLNDLDSFLDLTDSSIIYD
IKKKAKVCKYDEKLNHSLNLINSVIYDRNSEYTYKYISEINITEPKLIEYLKDITNEEKI
ARYAHGLSPDDIIIDWNYLNYGMGANDPLDSVYFYTSDNEDEAFIAHKEYRGTHPRYFEE
CNVRLYCKNKKVAHLAKQAHLNFISNEVFTASSPLHKKQKNC
>A0A245ZUQ6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sphingomonas dokdonensis|TrEMBL
MKLFHVSDVHFGAEDPKALDWFARCVADEAPDAVIMTGDLTMRAKPREFDAGGKWLMSLG
VPVTIEVGNHDIPYYWDPLRRLFSPYKRYGAAERLIEKPLDLPGVSIVPLKTTARAQWRW
NWSKGHVSSDALEDALRLVKAAPNGNLIFVAGHHPLIEGGTRGTAKTRNGDKALAAFADA
GVHAVLSGHVHDPFDKAVQCGNRTVRMIGAGTLSKRLRSSPPAFNEIRIDGGTFETLSRT
LSPEPKHSISDTVEVGAR
>A0A0M7A3M1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseibium alexandrii|TrEMBL
MTKIIQISDTHIVPEGTLAYGQVDTAKALAETVATINRLLPQIGPVDLVIVTGDLTERGS
EEEYGRFKALMADLDLPYRVLPGNHDRREPMRRSFADAHWMPRTGPLDWQIDLEDFAVIG
LDSLTANAAHGTLEPATLSFLTDALAHLSGKPVLAGFHHPPFAVGIEAMDAQNLRNASSL
GTALSRHTGQVLMVCGHLHRSIAGLFSGRLCQVCPGTSHAVTLDQRSNAGNSLTKEPGGL
LLHEWRDGGFLSHLVPIGTYPGGYPFK
>A0A1D3JR36|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas veronii 1YdBTEX2|TrEMBL
MPRVPTVTPDAPAVLVQLSDSHLFAEADATLVGMNTRESLQRVIGLVREQQPRIDLLLAT
GDLSQDGTLASYQHFREMTAPFGVPARWIPGNHDEPQIMAHAALHSDLLEPVVDVGNWRI
TLLDSAVPGSVPGYLQDSQLQLLAQALSEAPHRHHLVCFHHHPVPVGCAWMEPIGLRNPE
ALFAVLDRFPQVRALLWGHVHQEIDRERNGVRLLASPSTCIQFTPGSEDFNVSTEAPGYR
WLRLHADGRLETGVERVKGFAFTVDYASNGY
>A0A3G7X0U5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas orientalis|TrEMBL
MNRPFLVAQISDLHLKAGQRLTYGVVDTLGALRRAVDHLNASHPRPDIVVISGDLVDFGR
ADEYAVLHPELARLHMPCYLVPGNHDTRGPLLDAFGDHAYLPRSADGPLDWVADEHPLRL
IGLDSTIPGGHGGQLLDSQLQWLDEQLALRPDAPTLLILHHPPFISGIGHMDREPFINAA
ALERVVARHPQVERLLCGHLHRPMQRRFGGSLSCVCPGTSHQIVLDLQDAAPAHFNLEPA
GYLLHCWDAQQGLISHNGVFGEYPGPYPFYDAHGLID
>A0A4Y7R979|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pelotomaculum schinkii|TrEMBL
MGSKIKLTNSTGTKITNEELCTLGSQHAVITWVTPQQRADTSMYIGETPKHLKKHTFALD
SEFHYLEMYNLKPSTRYWYQVESNGVKGSLNSFTTLPAPKGKYLFSFAVMSDTHINYGEV
AEDINEIYFGKLVDYANPLLTQCILDSKRRNIDLAVITGDLTDTASRLQYLGLRNQLLPY
FGDTPYLLCPGNHDKYTKNSGLGEQGFLDNLADREKTYTSIIFKDYLFLLIDSCRQDENW
GDIDPVQMRWIESMLTTNKDRPAFLFLHHPCNGPDLWFGIKNNREFLKLTRSFPNIQGIF
CGHIHRNYVSVNRLMTGSRPYVEVPATVQFPCAYAVVRVYENGFAYNSYKVSRLDLSEMS
RERFILKKGGKAILTRYCLGRIGDRSFSYFNDQLFRPKQYELSVTLDNTNANKLYENARS
IDGASLIPAYDTKKAKVILGRYDSLHLTTQAFREKFFRYGAYARIMEVGNES
>A0A5K1I5B9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Halomonas lysinitropha|TrEMBL
MKKASLVKKAPLTRLAQITDFHLQADPEARGRSGSPLRQLEAVVAAVNRQRPSLVLVTGD
ISQDETAASYRLAEHALSRLEAPWYWLPGNHDQPALMEECRELHDEVDLGRWRVLLLDTH
VSGQPHGELGEAALATLDERLATDDRPTLLAMHHPPLPVGTAWLDEIGLVDGEAFWRVVA
PHCQVKAVIFGHVHQSFHAVQVLADGEVLAYGCPSTVDPFLPGSATFALDEASRPGYRLI
ELSDIELETWVERVDIRVLNSQS
>A0A2N7R850|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. AD21|TrEMBL
MDIQAKHPLRTDGPLDPDRRTLLKCSAWAGAGVLWALSGGIPKAFALDETGNVSDPKALA
STFHFVQISDSHIGFNKEANPEPVKTLQVAIDKVIALPKRPSLILHTGDITHLSKPEEFD
TAAQLLKGLPSTVHYVPGEHDTLDEGGGKLYLERYGKGTKGNGWYSFDDHGVHFIALINV
FNFQAGHEATLGADQLAWLADDLRAVSSSTPVVVFTHIPLWTVYQPWGWGTEDGDQAIAM
LRKYGSGTGLNGHIHQVIQKVEGNITFHTARGTAYPQPAPGAAPSPGPMTVAADQLRNYL
GITEVRATQGDHPLALIDSTLV
>A0A644T6U9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|bioreactor metagenome|TrEMBL
MKLFHISHTDLDGYGCQLITNEFFKDAIFYNANYGLEVKLSIKKVLDDIKNYKEEKILFI
ISDLNLTLQESEELDNEINILINDGFNIKLQLLDHHITGKKGAEKFSWYFLDDKRCATQI
VYDYLIEEFNAPITYLLPLVRAINAVDIWLENETKNFEFGKVLMSMITKVKEINNILFAN
LNREFKFYLLKNAIKFLDEENGHIKLDNEVHFMKKEFLKLDDTDDTLDNLSAVYLVKCLA
DIKDELTIFYKGQKGLLTYCLGSISIPANTFLRANSDYDFFIDINKKGNASFRADGKLDV
SLLASKLANGGGHINASGCKFEDFKETIDILEVKKYIQEKLDNLS
>A0A0E1S8Z3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Burkholderia pseudomallei 305|TrEMBL
MPARCRPRTLKDRKIVRQAIKRCNQISHPVAPHISPLLSIIYQKRQPARTTLNDRYFP
>A0A0J1FNF6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Desulfosporosinus acididurans|TrEMBL
MFIKRKNLEAGLLVLLIFGSLMFFLKVSSIRYQRISLKPKLVVPKADASGLAAKEKPILT
FGVVSDIHVQAKNNKAKLKFVKMLSDIKEHLNIHTLIINGDLGNGSSSDYAALRKLLVSE
ANNLKTFYTIGNHEFYQAYVNPKTKRWSPKTFPNNESDHTAINRFLSYTGQSKVYYDQYI
SGYHFIFLGSEKSAMSGGKYRDKTYLSKTQIAWFQKKLKENYVPHKPIFVFLHQPFPAAT
SGKWYRSIHNYVLQEDQLRTLLSNFPEVIVFSGHTHWLLGQGRDIMQGPFNVVNDSSVEM
PVDHNGVKAANESEGLKVTVYQDQVVIQGRDFANNTWITKARYNINLSKE
>A0A4Y8AGK4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mucilaginibacter phyllosphaerae|TrEMBL
MYNHRKLSILIFLLLPVFALAQVKPVASFRIVPLGVLGGADESNLSAYMLAPAGSANYIC
LDAGTIHAGIAKAVANKAFLVSESVVLRRYIKGYFISHAHLDHLAGMIMNSPEDTTKNIY
GLKSTLETIKTHYFTWESWANFADDGGAPQLKKYHYKALEPGTETTIENTDMQVQVFPLA
HANLTSTAFLIKSKDSYVLYLGDTGADAVEKSQNLHNLWAAVAPLVKAKSLKAIMIEVSF
PNEQPDKSLFGHLTPHLLMNEMQELEALSGTSLKGLNMVVTHLKPPHKSIIKIKQQLKAG
NKFQLNLIYPQQGRALNL
>A0A0J5NEU0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella michiganensis|TrEMBL
MLLAQISDTHFRSRGQKLYGFIDVNAANADVVSQLNALQERPDAVVVSGDIVNCGRPEEY
EVARQILGSLNYPLYLIPGNHDDKALFLEYLHPLCPQLGSDAQNMHYAVDDFATRLLFID
SSRAGTSKGWLTEETIKWLEAQLFDGGDKPATVFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQAIISTIPGTVHQVPYFHEDTRPYYDLSPASCLMH
RQVDEQWVSYQHPLTHYAGPWMYDENISCPTEDC
>A8I2W8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chlamydomonas reinhardtii|TrEMBL
LAGADAWQFDTWRLAEATSGHALSCLGFYLLQREGLIAHFRIRPHRLARLLRALEDGYRA
DNPYHSATHAADVLQTLHVIIHGAQLHVHYLDKLGLLAAYVAAVVHDHGHPGLTNDFLIA
THDPLAVRYNDRSPLENHHAASAFEQLLQPGHDITTGMEPSDRAAFRKQVIDMVLATDMK
QHFAILSHFNTRAHRTSDCNLPTITAPHSQSQLALKVADIGHLGEDLEVHCKWLSGLEEE
FFRQGDKEKELGLPISPLFDRAKQGVSKSQGGFFEFVALPLTHALT
>A0A5P9FDA7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sulfitobacter sp. THAF37|TrEMBL
MTRFIHLTDLHVSHPRSPDPSDKSGAVETLRRVVQIINGMERQPDFVVASGDLTNMGDAD
SYRLLKEIIAPLKPPLVMALGNHDKRAPFHEVIGNAESDAPYFHDAVHGGLHVITLDTMK
PGHVAGTICDAQFDFLANALSRHADLPRLIVMHHPPRVDADGLPWGSIDMPATERLAGML
REHHVAGILSGHIHINQVNHWHGIPIVISNGQDSTIDLLASDGLRIVEGTGMAICQWRPS
GLSVNFVPLSPEARELRMIDRARLLAFT
>A0A4U9T3I3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Staphylococcus capitis|TrEMBL
MKIGTISDLHIDRHPKLKPESYLNILAEVVNERKLDILLIAGDISNDYKMSYQFIVHLKA
MIQIPTYFIPGNHDLWSDGSDKSSTEILEFYKTQEECLIGRPLIVNDEWAIVGHTGWYDY
SYADKRFSLDKIKKGKHYGATWQDKVRIDWTTSDQQLSKVAAQMVDEDIKNVDDRNIILM
THVVTHPQFVVPTPHRIFDFFNAFIGTQDFDYIYEKYPIKYSIMGHVHFRKELRDSDTTY
MCPCLGYQRQWRTSDLAKEINHALIDFHI
>A0A1A6B0T1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium ragsdalei P11|TrEMBL
MNKKYLSMIIAALIAATSTIAPIYPVHAAYDSTTINTNLNSTVKPDHITLTWTKGPKTTQ
TITWRTSTNVTKGLVQYKNLTTGEIKTFNAAKQNFSTSSTDINTGYMNLFSATLENLTPG
TKYSYKVGDGQNWSTENTFKTESSKEDDVKFIVFGDSQSGNADVPNYAPWNKTVQNAYSK
NKDADFMINVGDLVEKGQDYRHWNNWFDAAKGVIDNLPEMPVQGNHETYNAVGWDSTKPK
YFTNQFKVPMNGPDGFKGQVYSYDYGNVHFVMLDSQEDEESPNNDEFLKKQATWLDSDLT
SNKKPWTIVSFHKTPYYNKASRANVTLKNIISPVLEKHHVDVVINGHDHAMSRTFPINNG
KYYTDYSNGTVYYVTGRSGAKYYPDLSSKVWDAFFFDPQDMPCYEVADVKGNVLAINAYK
QDGSLVDSFVIDKDHPQNSTKVVLPTAYNVDMNNKELAAIGADPRLVVYGTPIAFGSNQS
EIIKGKAYVNPSYIAMYLGGKYDSSSMKLTIDKQTYSFNSKDLSPSKNVSLDALIRAGFN
CSYNTQFNMIMIDK
>A0A1A6ALA3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium ragsdalei P11|TrEMBL
MQRFRVVMKKSISCLCILVMLFSAFLVGSPLTVEAKTANNPPATGGLQVDVVKNGSPEQA
ASFSIEDLQGWSQHEEKYSSIDSMPAPVGTLASGIYLSQVLQASGIQNTSDVASIKLYAA
DGWSHVFSSDYLFGNPRYYYPNLISSWDTDNQKPGSGAGSNGVEVQPMFALNSYQDRYLD
LTSQNAVDEVKAKMNGASMLRFCLGEKASDVEGNGTVTTNLIGKWIYRMDVTLNNGVTPP
PTNTLPMQSPILSASYTSQGTVTGTVGQSSPINITFSDNADWRNAITGIEVNEKSLTSDQ
YTASPGQITISASAFPAAGTYSVVIQAKNYTDDCATQIMTVPSSLEAPVPVLNGEILSWK
AVAGASGYKVSISPAVGKAITKTTADTSFDLSGLALESGSYSITVTAQAPAGSTQCSDSQ
ASAALTYTVGSGKTGPIFTAEGTGNIVGKAVTITYSPSDTSYNQSISSVTVNGVTVDAGK
YDKTVGGQLTIDGSLFPKAGDYVIKVMASGYQDTAVIQSVFDSTKALATLNLSGSPSLIY
NGEPLHFVLSNLTLVGKNQYGDSYDISGKPVIWKVESGPATVLGSTLTINGSGKVTVSAS
IGQIVSNELKLRVGNSGGIDNPGYPDEILLSWKEDPKTTQTVTWRTGVDTTQNQIQYMPA
QNYSGSFSGGQSATALQSDLYDKNYHFEVTLRGLTQGTKYVYRVGREGAWSQPAYFTTGG
RDKDFSFLYMGDVQEGIEPWTDLLKDVYTQNPNLKFGLMGGDLINVANSTSEWEHLLNGM
SPVFNQIPVMPTVGNHEEPTPGDLKDYPLYWNSFDFPDNGPEGYKKQFYSFDYGNCHVAV
LDSNIMGTTTPGSNDYNKISLWLQNDLNSSNQTWKILVFHHPPYPVVADAYCANIQKNWA
PLFEKCGVDVAFVGHQHVYMRTKPMYNGQVQTDPQKGTVYIIGDAGSKFYPPGLDKKYQY
YIDKQIPYKSNYQLVNINGNTMTIVTKDSQGQEIDRYSIEKSPAVYTVTPMANEDVYETG
TTSDGINTMTVKPGVSGMKYFSAKVTPVKEHRGEESAVFVQIRNGVQVRSSVAKANFDVV
SSAQAGFNVQAGDVVKVYMVDDLTNDLDLNPAVLQ
>L0DSX2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thioalkalivibrio nitratireducens (strain DSM 14787 / UNIQEM 213 / ALEN2)|TrEMBL
MATTQPTATLVQITDTHLGRSPRPLRPGYPDSDVQLEAVLADIVEQQPFPELLLVTGDLA
EDPEAQAYHRLESRLAALGAPILALAGNHDDPGLARKTFVAAGHGFDDEYRLGNWLVVGL
DSCWPGHAAGRLRPEELDRLKECLARHPEHWVLVAVHHPVVPVGSLWLDAIGLQNGSDLL
AVLERHPRVRACVFGHIHQPFDAMHGHLRLLGSPSTCVQFLPGSEDFALDPDAAGYRVLT
LYPDGRLETDIRRVAGTGPLPA
>A0A2G8XXJ4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii COUG|TrEMBL
MLTVFLFIGRHATELQQRHTFYNWL
>A0A1V0PSW6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodovulum sp. P5|TrEMBL
MSDRLKLIVLSDLHLVPEGQLSHGLDTADRLRAGIAAINARHGDADCVVLAGDLADLGER
AAYERLRDLLADLTVPSVVTIGNHDDRAAFLEVFGQDAAAATGFVDAVRDIRGQRLIVLD
SEGGKDGAGRLEPIQLNWLRDRLAEAADRPVIVILHHHANPLSTAVDRIILENAKALVDV
LKTHPDIRQVIAGHVHYTSTALWHGVPFTTLAGSHYNVTIPLAPGVAVHRLDGPAQMAVV
LSDADQTLVHFDNYIDGHGVISVVAPKAAEKLAPVSG
>A0A6B8N8Z0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio sp. THAF191c|TrEMBL
MSTVFQISDCHLSDESSFQNLEKALNVANADSDCDTILLTGDICCGPKSGDYTKLLSFVS
QHVDSKKQVYAIAGNHDDIVLMKDELKGSLIQVVDQCEIAGRHFVFLDSSQKPIDAQHPL
GSGRIDNRGIAHLRKQIRKKKKPIVVVHHPVIRVGSEWMKAICLENDQQIFNILKQSGVR
EVICGHGHDHITCTKEGVTQYMAPATAYGFDHSIPEYNRSERIGMNKFTISKQTITVNEV
VL
>M1WQB6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Richelia intracellularis HH01|TrEMBL
MSDTYPVSVAQITDIHLFADENQELLGIPTKDSFCAVIEHLGNLDTEIDMLLLTGDISGD
GSPESYENLQNLLYPLRLPTYSVPGNHDCSNVMKEVLNLKLFSRRKSFERGGWNFILLNS
CISEQAHGYLSIETLDWLDTQLTTLDSKPTLIALHHPPFLINSQWLDKSRLQNPEDLFAI
IDRHSYIKLVICGHVHQEFQYQRYQVNYLSTPSTCIQFQPNSPDFTLDDKQPGFRYLKLY
SNGDWESWVERVPFFYPLNLLNTGH
>A0A5C5XEF0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rubinisphaera italica|TrEMBL
MPIHYTRLHRREFLQTSLVAGASMLTFGQVLGDDKQQNVPEHVALLSDTHIDADATKVVR
GSVMSANLQKVIADVIAQPQQPAQAFIDGDCAFNVGLPEDYRTLASLLVAFPAANIPLHM
ALGNHDDRTAFLKQFASLNEETQAVEGKHVSRIETKHANWFLTDTLQKVNNVTGEIGAQQ
LDWLSSALKANREKPAIVLGHHNPQFDAREDARVTGLQDSLALFELLESLPHVKAYVFGH
THSWSVKQRDSGLHLINLPPIGYAFNETSPIGWVDAALTATGMQLTLRCTDPNHAQHLTQ
QELAW
>A0A378HXP5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Legionella beliardensis|TrEMBL
MKIIHISDLHFGMHYPHILTAFLEEISTLKPDAFIISGDLTQRAKTHQYEELKKFLEQLP
GTTFIVPGNHDIPLHNPLARLLYPFRNYKHYVTSDMPVTFTNSEIRVLGINSVNPYQIKD
GELSHKTLEVITRYFDTQDNKLNILFFHHNFDYLEGLHKPLQNDQEFLKYLKQSTVHIVC
TGHLHYAHLGLIEKDNQDSCLVLHAGSLMCMRSKDGLNSYYIIENDGLACRIHWRVFCDK
QFLTRSIHTIDFTKKRALLESLMQPAPEAS
>A0A7D7X7N1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio spartinae|TrEMBL
MDKIVQISDIHFCMKDKSHSSRKNLSLVLNKINGLYHEYILVLSGDLVMKADSAHYMALY
QYIRAFTRNEIYAIPGNHDDIALMKKLAIQEEFFKIQDLLEIGINDIVFLDSSEKGEHLG
GGKIDLAYFEAIKSKLRENSNKIIFIHHPPFKIGAEWFKKICLDNGDLLMKSLSEINNLK
YLAYGHCHNYFIEERENTVFLSCPSSWVQFDHTEHHETKYDQQKEIGFNVFHLSDDISHE
TVTISVC
>A0A086QGS3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii MAS|TrEMBL
MFFSIPPRRACVPLDVHLLDVSFPGSCVAPAPALKCFFLLLGDSQDYHMVRSLIIDLILA
TDMKNHFETVSRFRVRRNALDFDLSSEEDFWFAVKIIMKCADLSHCSVPWSQHFQWCQRL
SVEFYDQGDEEVARHLPMSPLCDREKHSEVAKSQLGFMSFVAVPLFEELMAIDGTGNIEK
YCISVMKTNASHWEALSSAAVPVPLLGEAPSPDVAPPLLHLIDGSGAAAVHPGSKAAEIA
NRYASSTVTTLDLTCLVYRTQLNRARRSSQQSGRRVSEGTSA
>A0A517XJ23|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia maris|TrEMBL
MKLQSQSPIKSLGRRAFLKNGALVLSGLTFPALRRQVSGAFDTNQRGAVRIGLVTDLHYA
DKPPAGSRHYRETLAKLKEAATQFHSDRPDFVVFQGDLIDSGKSLAQEKTHLQTVVNAIS
AIPFPKYYVLGNHCVDQLTKNEFLQGVGQKESFYSFDRNGYHFVVLDSCFKSDGTPYGRK
NFKWTDANIPSEELSWLQVDLKQTMLPTIVFAHQPLDLKDTDAHAVKNSSKVRNVLEQSG
KVTAVFQGHSHHNKYSEIKGIHYCTLVAMVEGSGLDNNGYSSLDVYEDGSLVLNGFRKQK
DYHWS
>A0A1A8TGE0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Marinomonas spartinae|TrEMBL
MLIAQLTDLHIKKQGKIAYQKVDTLQCLKQAVTHINGLSPQPDWVVVTGDLGDFGVPEEY
DVLVPELKKLHAPVKVIPGNHDHRAYLRAAFEGFSSFDHADYCHFSHVVDGYHLIGLDSS
VLGKPYGQLTPDSLEWLATQLADKCDLPTLIFLHHPPMKVGIDHMDVQKLLNDDELWQVL
EPYKQVKGLIAGHLHRAIYATWNGLPVWVGPSHSHAVTLDLTPNAPSRFSLEPPAIQLFK
LAPDSIVSHISYIEVGEKSAGPFPFFDENNKLID
>A0A084A4W3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serratia sp. DD3|TrEMBL
MTQPFMIAHLSDLHIKAGGRLSYKKVDTLGALYAAISKLNRLIPKPDIVVISGDLVDFGR
DDEYHTLRQALSTLRIPFYVVPGNHDDRQALRRAFSDAQYLQPQTEFIQWVIDDYPVRLI
GLDSTLPGKSSGLLCPQRLLWLEQQLALCPDQPTLVILHHPPFVSGISHMDKQRLENPQD
LASIIRRHPQVERVLCGHLHRTIETRFAGTLACSAPGLSHQVALDLRTESPAHFVLEPAG
FLLHCWSEEQGMISHHCLVDDYDGPYPFYDAAGLID
>A0A5E5QJ91|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Gammaproteobacteria bacterium|TrEMBL
MKHFIQISDCHIDDNTQTMGVNSHENLTKVVDKITTLQSDALLISGDLTHNGTLHSYKKL
KAILTPIETDIFVITGNHDDSDNLASEFGACLFDCMTLGAWDIVNIDSVQIGKTSGFVTT
NALTTLDKQLQHSNTKYSLIVLHHPVVPMNSAWDDALSLENPQDLFAVLDKHPKVQAVLF
GHAHESVEFDKNGLKIIACPSTATQFNDERRIGFNYYTLFDDGRLDYETQWINS
>A0A1V5VA71|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|bacterium ADurb.Bin236|TrEMBL
MKSLNKILAVALSFLTFATARAAAETGAADALKHFNSDEALKLDASDCSAGFSFAVMADT
HQSESVFPRFVRMVADAKPAFAVTVGDFTNNGLAEEYSRYVETISGAGVPWFSVPGNHEY
RTPAGRTSHDGKKRFEKIFGPADFAFEHCGWRFALLDVVAYDLLSPSQLKKLDRALSGSG
GRAAMFAHYPPAIIDKWAEGIWVSGAQDAMRLFKERETRYFFGGHIHVHDSYVAGPTTYI
VTGGGGGGLDSDYSPQDLWSPSAGPFHHFIMVNVKDSESSFRIVKLEE
>A0A1J5PYD1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|mine drainage metagenome|TrEMBL
MTTLLVQLPDLHIREPGRLAYGRLDTAPYLSLAVDTILRQAQRPDAVVVTGDLTDFGRAG
EYAHLRSLLAPLTMPLYLMPGNHDDREQLRRSFPEHAYLGSNGFVQYSVAVGNLQLIALD
TVVPAASHGSLCDQRLQWLSDTLDQHRDRPVLIAMHHPPFPTLIGHMDQIGLLQGAVELE
KLVAMHPNVERVVCGHLHRSIQVRFGGTLAMTVPSPAHQVCLDLDPNAPSAWALEPPGFA
LHALSDTRQLSSHNVASGHFDGPHPFHAGGQLID
>A0A1J5QX56|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|mine drainage metagenome|TrEMBL
MTVGTQSFATTAERTLVRGEPGPLGWSELVVGPGEAHHGDAPHGAGEALACLVHLSDLHL
CDAESPARQEYLDRHGDPGAPYAGRLGTIGTYRPQEILTVQVAAAALEAVQRLDRAPVTG
APLDAVIVTGDLTDNAQRNELRWYTSLMAGGVLAPRSGDPRHSGWVGAVDAVWSSSYWHP
DGAPSGESPDRPTALYGYPVVPGLVEAARAHVLSPGAGLPWYSVHGNHDALLQGTVAPDP
ELRRLATGDERVVDLAAGQTPLVILEGAAPIGPARYTHDATSPRESVTADPSRALVRPGE
FDEAHAGADQHGASRVAGNGNSWVCDIGQVRVIAIDTVNPHGGWQGSVDAQQLAWLSDQL
DRARGRYVVVTSHHPSWTLTNPYAPDGSPRRHLADDVLGLLLRHRGVIAWLAGHVHAHTH
VWHQAPDRDGGLWEITTSSLVDWPQQLRVLEIVREPGGTLALASTVVDHVGAPEWDPEAL
GDTANLAAVSRSLAVNDYRARNVPALLARTAGTPADRNAVWRMPDPHA
>A0A0K8NVB6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ideonella sakaiensis (strain NBRC 110686 / TISTR 2288 / 201-F6)|TrEMBL
MPRLPFAGVPTPTPPTSPPTSPRRDPGLRRAAGLPALLAACLLLARPALAEEVAASPGPA
PAFDVVVLGATGGIQDGNLSAFLVRPAGAARGVACDAGSLVNGIRVAEARGAFDDLALPA
DGRWTRVGHVLRDVIQGVLLSHAHLDHVLGLVIASPDDAPKPVYALPSTHAALSASVFNW
SAWPNLSDRGRPPRLGTYRLQDLAPGVRQPLVGTALGVTAYPLAHAGTESTAFLIDHGEQ
ALLCLGDTGPDPVERSDRLQSLWQAVAPWLRQGRLRAIIVEASYPSDRPDALLFGHLTPA
WLMSSLRQLAGLVGPEALRGLPLVVSHVKFGLEAGPSPAQRIERELEAANDLGLRIVMPR
QGDRYRF
>A0A0S4TTI1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ralstonia solanacearum|TrEMBL
MHFLQLTDLHIKQPGRLAYRRVDTAAYLSRCVAHVLAQPARPEAIVLTGDLVDAGAPDEY
AHLRALLAPLDAAGIRMLPVLGNHDAREAAREAFADWLAPIPAEARDPDAFQYWTDIGEV
RLIVLDTLDTGCPGGRLGVPRLDWLHDALAAETARPVVIAMHHPPFATGIGHMDVQSLAA
DDIPAFAQIVRAAGNVERILCGHLHRAIDVRFAGTVASTCPSPAHQVALDLDPEGTPGFV
MEPPAYRVHAWVPGQGLVSHLAYVGTFDGPHPFFEPDGRLID
>A0A425HL86|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii CAST|TrEMBL
MWFYSYLRHPNDVPSLCTHIRSSNIFLRLGPQYYLPEDERKSLFVRTCHLLYYLASLLFL
TTLTTYTAIKIPSSPSTTTELLSQLFPFNSIDDCNERLSCKVDCVLYAFPDLNCAKDDGS
LLTFGGNSYSSLYFYHYPGKDVPLQKEARTAWERCYQIMRETTGRLQFLQQDRETVERTH
TCFAGCKTNGAVTFTQKLTDGTPVVFDSGTDWLQMAPAGSLPQDTRPACNPSEPPSLLCV
EPTDECQHVTLRYQVCIGDTAFCFDIVRILITIALGVVWNVVLDAFVVWAMSIDDSDPQN
LGRVASKCGLQIIATAIIVSSFFCLVASMTRILSMDANIARHGTLWTSFVLVIIIDQLFS
FLFSVLIWYAMLRRCGRQLPDESRFQYKIHPSPVLVKLKKATRKIVNYNGFEMFFTMLLG
WMVVDLTCRMILCQFFFDETAFLNQADRILEVVDFIILILFIVEICLRIAADGLKIYFSD
PINCIDFFLVFFGFGIRIVDFFIQINKGIGNVLFIMRLVRLYRLHRPPTGSLAIGKKEVF
TSRVERIIAVLNKALEIEELTTREKDSLKWLIQTISSGKLYEMGSEEKKKTDSHVQAWIS
IISTQSQSANQMADDMENILLERVKQMTKAGDAETDMPAVLQLEYGIDVSLDHAIEGYLA
NNLITWNFDVFRFHVIAGRAALPKLFVRCLQHQEVCSLFNLKIENMLRFAMELEKTSFST
TPFHNSIRSAEVLQAMHLFLAFFDTQIKGFFNSREILAALLAAVVWDYQHPGFSSAFLIK
TQHAIAIRYNDRNVLEHHHVAAAFSLMQKLGENDPLLAFPEDQYIALRKIIIQLSQSGSR
SNQTACLSLLKTKLQQAEFPRSITEDKNIILCNLMNAANYSFLGRPLQLYLQWSQKYMEE
LFMQGDRELELDMPITKNCDRHTTSEAVVQLGLIDGWAIPIYTTLAQTVPKLNAIVVSHL
RRNRLHWLDEQQEEDKSKEKQTKVTPIKRYSKTKQGSTEATGNGELSKPEATTIEIADGT
AGVPELRANANPLSEVD
>A0A3R7YVW4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii CAST|TrEMBL
MHRLLDWDFHVLALPPASAVLVTRDLLTQFALKANMDIPGEILMAFSVAIYKNYRPNPYH
NFYHALNVTQVLCLLLALPDVAAQFSPIDYLVLSVAALGHDLGHPGANNLFMTRFDCWPS
RIYQNVSVLENYHAASLFQILRHPAFNVFCSVSPTNFAPIRKRIISAILWTDMAKHFDVV
AKLQAKIQGEMVLAEGIIVTLTKPYLEGLLLHAADISNPMMDFELCRDWAFRACDEFYQQ
NKMEEMGGFPPSMPSFEHFDEYNVAKCQVGFIDAICKPLFNSLALMFPAQLGDRATQLQK
NRCVPLIIFPT
>A0A3R8AS37|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii CAST|TrEMBL
MAAESSPSGPIESAGLAARDESPTRSSTSSLDPDQQTCEHASSLPSLRESPRASASSSGV
ASKAGEGPRLLTFLPQRLHEATPPQDGALPAASGHGHTDAETHAQGANPGEARPEIQAGS
DSDSKTSSSPLSFLTSLAVASKQKAHAEGLSSHASSISGKRRAQGVEKLSVGSSKTALVS
LDEESDVSGADSAASVLSSQWASGEDRTIGAKPVLDRARWTTTAHDATTHGDASAETLTT
PEGIQSPPLSCIVAVEEQTVPPWEERGIVEGVGVVKASSLKKSGRRPKAIHFREADSEVS
APSFSDMPSLGPGMGRQESDLEGRSNGEVFRPMHFSEDDEEEDEEETKRYLGRSQTGDPG
WRGMRWQMRSMWRYVAAINNDEATMKNATGPYRVLRGCDCKCFPLAFKERRAECDYRNFN
IRRMPLRLVIMFPVLCTIYAISYGTCRRFCPDCYLAAPFDGELVVSVFLLTVATLGAHFY
LLYEYLELFVVLTLCLLSTYRSAMRLSTLAGAIRDPANFGVIFPYYGINGILESFLLCFT
IVTFLGVRFAYAMWATLYFLAWSAPIAILSMHLSVKLIREPERVWSEWEGLLHILPFLLI
VLTLVSAYYEERKKRVLFWNLRVRPETLT
>A0A378JCN1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Legionella gratiana|TrEMBL
MKIIHISDLHFGMHNPMIIESLLDDLTLLKSDVIMISGDLTQRARPEQYKQLLGFLQRLT
IPLLVVPGNHDIPLGNPIYRFLYPFKRYKKYISAQLEVSFNNKEVNILGVNSATPYQIKD
GRLSQKTLERIKNHFSYTSTQLNILFFHHNLKYFSGMHHPLNNAEEFINYLRESPIHIVC
TGHLHYANLALITKNQGEQCILLHAGSTSCLRTKDGKNSYYLINTDHLKCSIDWRVFVNN
AFISHQIYKLDFAS
>A0A3S4E1Y7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salmonella bongori|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLDAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFSPRCTVRYKTRGSPRPSAC
>Q4KJ96|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)|TrEMBL
MPSVSALTAADPVLLVQLSDSHLFAETDGTLLGMNTADSLQRVIDLVLAQQPRIDLMLAT
GDLSQDGTLESYQRFRQLTRQIAAPGRWLPGNHDEPQVMEQAASGSDLLDPVVDIGNWRI
TLLDSAVPGSVPGYLQDEQLQLLTRSLSEAPERHHLVCLHHHPVSIDCAWMEPIGLRNAQ
ALFAVIDAFPQVRAVLWGHVHQEIDRLRGDVRLLASPSTCIQFEPLSDDFKVEEQVPGYR
WLRLLPDGRLETGVQRVEGYEFTIDYGSEGY
>A0A2U3MWN0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acinetobacter stercoris|TrEMBL
MITTKDSDPSSKIIIQITDTHLLADPDAEFVQINPERSFHAVIADILEQHTHIDAIIHTG
DLAQVARPETYQRYLDYMTKLNIPFFHIPGNHDDIRYFPFHTPDPKPTVVDLDQWQIVML
NSAVQGKVHGWIQSEQLEYLDQWLNDNRDKHVILACHHHPFAMRSKWIDQHILKNTHDLT
HILEKYQHIKAVLFGHVHQESLNQWNHIDFLSTPSTFAQFKPQSENFAFDEVAPGYRYLH
LKSDGQFETKVKRLKGFFQKINKEISGY
>A0A1R7QGI1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acinetobacter johnsonii|TrEMBL
MTLNNEKNWTIIQISDTHLMDQDHLEFVHMNPEQSFHHVMQHIVERHPQLNAIVHTGDLA
QVPVPRTYQRYLDFMQSLKTPFYQVPGNHDNAEHFPFHQQQNKVHVIHFGPWSVVLLNSA
VKGKIDGWVDETQLNQLEQILQEFAQQHIVIACHHHPFEMQSKWIDQHKLKNTQDLTAVL
AKYHNVKIVLSGHVHQESWREWHGIQFYSTPSTSVQFKPLSDHFALDEQAPGYRILQLNA
DGSHETHVERVLHAQQKINVEISGY
>B6IMU0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodospirillum centenum (strain ATCC 51521 / SW)|TrEMBL
MRRIAHISDLHFGRIDPAVVAALRDDLAAQAPDLIVVSGDLTQRARPSQFRAARAFLADL
PAPHMVVPGNHDLPAFNLLARLVDPLRNYRRYIAEDLDPFLNLGNLAVLGLNTSRSLILD
FAEGRVNQRQMDRILGCLRELGPEVFKVVFTHHPFLPPPDHPGRRLVGRATRALRALEAA
GVDLLLAGHLHRAYSGDVMSHHAHVERSILVAQASTATSTRLRNEPNAWNLIEIAPPSLV
LRLRTWEGERFMPGLVTAWEKHGPRWEKRGEDTGLAELDRRLAARR
>H2Z2W2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ciona savignyi|TrEMBL
RVVEIPDDEVPATLSGEGPVPPEIKRWLVQTFTSRRADVRGRKESETRRSLRSVVHAVQA
GMFVERMFRKTSVGVQNLPPEVQEHFKNIDSWSYDVFELDRISDGNSLKFVFYELLNKYD
LIRKFKIPLKSLFAYSARLQRGYRKYNNRYHNPIHAADVAQSLNCLLVSSGFVHWLSDLE
MFSMIMAAVVHDLEHSGTTNTFHTNTRSPLAQMYNDKSVLENHHISSAFRLLNEEDCDIL
VNFSKDDYPSKEARTLMIDMVLATDMSQHFGQVKKLQSNLQHPESLEKSRAMCLMIHSAD
INHPSKQWELHCRWTERLVVEFFEQGDQERKLGLPLSPLCDRHTTMVAQSQIGFMDYVIK
PTYDVLFDIFRNVNGPV
>A0A011NVE5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Accumulibacter sp. SK-11|TrEMBL
MRIVQLSDLHLSSQPLYGVVDTLAALQLALRRVVASPAPDLLLLTGDLTSAGGGEEYALL
RSLLAVLPFPCALLPGNHDDRDRLRAVFPGQAWAAAPLCCQRLDFDGGTLLLLDSIVPGE
EWGEVAAPQIDWLEAACPQRRPVLLALHHPPFNVGIAGMDRIRCRGEALLAAWLARHEQV
EAMLCGHVHRFVSTTFAGRPAIVAPSPAHQIALQDGPLAYTLEPGGYLLHDWSPGERLCS
HYLPVATSLTQCYGDG
>A0A8C7EMT5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Neovison vison|TrEMBL
MGSTATEIEELENTTFKYLIGEHTEKMWQRLKGILRCLVKQLEKGDVNVVDLKKNIEYAA
SVLEAVYIDETRRLLDTEDELSDIQTDSVPSEVRDWLASTFTRKMGMMKKKSEEKPKFRS
IVHAVQAGIFVERMYRKSYHMVGLVYPEAVIVTLKDVDKWSFDVFALNEASGEHSLKFMI
YELFTRYDLINRFKIPVSCLISFAEGLEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGI
MSDVALLYNDRSVLENHHVSAAYRLMQEEEMNVLINLSKDDWRDLRNLVIEMVLSTDMSG
HFQQIKNIRNSLQQPEGIDKAKTMSLILHAADISHPAKSWQLHHRWTMALMEEFFLQGDK
EAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEPTFSLLTDSTEKIITPLIEEASKTDTSS
YGASSLSTFILHSVDLFRRSNMKGTMNDGTYSPDYSLTSVDLQSFKNNLVDIIQQNKERW
KELAAQGEPDLHKNSEDLVNTEEKRADAHS
>A0A166DA30|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Methanobrevibacter filiformis|TrEMBL
MTFIAHISDLHVGTKGFNKDSLLYIVDEINSLKPDLIVLTGDLTEKGYYSEYLEVVEYLN
LFKSPLFSIPGNHDSRNVGNESFEEIIGERNWARKIDNGEEMLLIGLDSSEPDIDEGHVG
RAQQIWMENILDEAVTHSLFSIVAIHHHVIPIPSTGREKSVLSDAGDVLKSLIDNNVDIV
MCGHRHVPYLWKFENTLFISAGTTSSTKLRGKSLNSFNTYDITENRVDAILNQIDGAKIS
LGNLKRAF
>A0A2K4WKF2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas syringae group genomosp. 3|TrEMBL
MPSAAPSSSVLLVQLSDSHLFAEADGALLGMSTRDSLEKVVEQVLVEQPQIDLVVASGDI
SQDGSVESYEAFRRISARIAAPARWFAGNHDELPQMEHVAQGEGLLDPVVDIGQWRVTLL
DSAVPGSVPGLLADGQLQLLERSLREAPDRHHLVCLHHHPVAIGCDWMAPIGLRNADALF
TVLDQFAQVKALLWGHVHQEFDQVRNGVRLLASPSTCIQFAPGSVDFKVDTLAPGYRWLR
LHDDGRLETGVSRVVGMVFEADYGGTGY
>A0A840BJA9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Niveibacterium umoris|TrEMBL
MEVRVLGCSGGIGGLDVRTTSLAIDDDILIDCGTGAGVLDVPALVAIDHVFLTHAHLDHI
AYLPFIIDTVGDYRDRPLTVHAAPETLRIIRSHIFNWLIWPDFSAIPDRAHPLMRFNELR
VGESIDIGGRRITALPALHAVPAVGYQIRSERGASLVFSGDTTLCEPQIAAINAIDELRV
LIVETAFPNMQHDLALAARHLCPQMLFSLLDRLIVSPDVFITHLKPAQAAEITEEIATYA
GRLRPQILKNDKVFRL
>A0A086L217|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii p89|TrEMBL
MWFYSYLRHPNDVPSLCTHIRSSNIFLRLGPQYYLPEDERKSLFVRTCHLLYYLASLLFL
TTLTTYTAIKIPSSPSTTTELLSQLFPFNSIDDCNERLSCKVDCVLYAFPDLNCAKDDGS
LLTFGGNSYSSLYFYHYPGKDVPLQKEARTAWERCYQIMRETTGRLQFLQQDRETVERTH
TCFAGCKTNGAVTFTQKLTDGTPVVFDSGTDWLQMAPAGSLPQDTRPACNPSEPPSLLCV
EPTDECQHVTLRYQVCIGDTAFCFDIVRILITIALGVVWNVVLDAFVVWAMSIDDSDPQN
LGRVASKCGLQIIATAIIVSSFFCLVASMTRILSMDANIARHGTLWTSFVLVIIIDQLFS
FLFSVLIWYAMLRRCGRQLPDESRFQYKIHPSPVLVKLKKATRKIVNYNGFEMFFTMLLG
WMVVDLTCRMILCQFFFDETAFLNQADRILEVVDFIILILFIVEICLRIAADGLKIYFSD
PINCIDFFLVFFGFGIRIVDFFIQINKGIGNVLFIMRLVRLYRLHRPPTGSLAIGKKEVF
TSRVERIIAVLNKALEIEELTTREKDSLKWLIQTISSGKLYEMGSEEKKKTDSHVQAWIS
IISTQSQSANQMADDMENILLERVKQMTKAGDAETDMPAVLQLEYGIDVSLDHAIEGYLA
NNLITWNFDVFRFHVIAGRAALPKLFVRCLQHQEVCSLFNLKIENMLRFAMELEKTSFST
TPFHNSIRSAEVLQAMHLFLAFFDTQIKGFFNSREILAALLAAVVWDYQHPGFSSAFLIK
TQHAIAIRYNDRNVLEHHHVAAAFSLMQKLGENDPLLAFPEDQYIALRKIIIQLSQSGSR
SNQTACLSLLKTKLQQAEFPRSITEDKNIILCNLMNAANYSFLGRPLQLYLQWSQKYMEE
LFMQGDRELELDMPITKNCDRHTTSEAVVQLGLIDGWAIPIYTTLAQTVPKLNAIVVSHL
RRNRLHWLDEQQEEDKSKEKQTKVTPIKRYSKTKQGSTEATGNGELSKPEATTIEIADGT
AGVPELRANANPLSEVD
>A0A2S2E607|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Saliniradius amylolyticus|TrEMBL
MITNSARQLTAIYQLLDQEQELMAVYGQLEPLILDLFDAERMSIFQRRRQHQDLVARFKT
GSEVKEIKVPITPQSIAGYVAMSQLPLVIDDPYDSQALTEIHPRLRFQGKFDKSSSFITR
NIICVPILNAGVLLGVLQIINKRHGDFNNEDLQTAQELAERLGDAFRFELGGTNKPFQYL
VHRGLIGEKQLDELLQKARDPKELVQKLSSEFRIEEKELGHALSVHFQVPFIGYDPEKYH
LYQSDARLNLSYLKRNYVAVVADVRENPIILMAEPNNAALLMEIESALGINSYDINVALP
NTVLQYLGESVGGSGPGDMDEILDEISSGSDEDEESMEEPSDDAPAVVRLVSRILHDAKR
LNASDIHIDPEKRGPTKVRMRVDGVCREITQIPASHHNAVIARIKIMSHLNIAEKRVPQD
GKLAAKMGGRMVEVRVATIPTVAGEGVVMRILASGGAMPMDKLNLAPQVDKTLRTMIKKP
HGIILVVGPTGSGKTTTLHAVLGELNTPEKKIWTAEDPVEITQSGLQQVQVSPKIGFTFA
NALRAFLRADPDIILIGEMRDKETAHAGIEASLTGHLVLSTLHTNSAPETITRLLDLGLD
PVNFSDACVGILAQRLIRTLCSNCKEAYPATEADIGFIRRQYGEQYLDELDGYEEPLTLY
RAKGCDQCGDTGYKGRTGIHELLSMTSELRALVYKEASAAEMKTQAMKDGMRTLTQDALY
KVLKGDTDIAQVQIVSGSD
>A0A376FCF4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Enterobacter asburiae|TrEMBL
MLATPSTCVQFKPHCANFTLDTIAPGWRWLELHADGTLTTEVCRLTGAKFRPDTASEGY
>A0A890DK22|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli|TrEMBL
MSIKNDGHYFCRAGGNRPDGLNEPVTINKKINAKDRAAIAAALESVKLSDISSNLNRFSR
GLGYAGKFTSLADWITEFGKAVRTENWRPLFVKTEAIIAGNAATALVALVFSILTGSALG
IIGYGLLMAVTGALIDESLVEKANKFWGI
>A0A0P4UPM9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Leptolyngbya sp. NIES-2104|TrEMBL
MTDLHLFAKSGQCLLGMPTLRSLNALIEQFQQLRPKPDLLLLTGDLSQDGTIESYDRLQR
LLSPLQIPIYWLPGNHDCIEVMERSLTQFLPDKTFEQNGWRFLLLNSQDPGCVHGRLSAE
SLNWLDRQLSKHPNFPTLISLHHPPFAVNSTWLDTSILQNTAEFLEIVDRYPQVKLIVFG
HIHQEFQRQRNTVTFLGTPSTCIQFARESDDFALGQEPPGFRLIELYPDGTWTSQVKRVQ
FSHVLDLAATGY
>A0A3B0LYP8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Arsenophonus endosymbiont of Trialeurodes vaporariorum|TrEMBL
MENKIEALNSTYSIFVMSNSQTWRLTLADNDPNDHRSRWHSKLNPVRNSIVSLNNSLHVT
FGIINGDLTEYGRRSQRESDREFFSLNALNVDVYVGLGNHDYQNNVGNCSESSNSDYSMN
ACARGMVFDMHYRIEEYRHYPTSINFSYDSGEYSGSKAYSWDYGDIHYVQLQNYPTYHVV
LDHWAAATINVTQSMDWLESDLKSAKQRGKTIVFNIHDGTDHFIHQSSTEEKNRFRRFMS
DYNVKAVFVCHTH
>A0A1E1VDM7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bosea sp. BIWAKO-01|TrEMBL
MQRVVQISDTHLSPGKPHFACNWEPLRAWLAGQGPDLVIHTGDVTVDGADVDEDMRHCRE
LLDALDLPVLSIPGNHDVGEAWHPHQPVNAERLARWRSHLGADFWSRDIEDWRLIGLNSM
LFGSDEADEARQLAWLEQEIADAQGRRLGWFLHRPLFVETPDEGDKGYWSVPPRPRAHLL
DLVRRHDVAFVASGHLHRAHDFMVEGTRYIWGPSSGFVVGPELQPGMAGSSTLGAVTYSF
DGRDFSAAIHEIPALTTLWIDDVIHEVYPPRAA
>A0A087RT73|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Marine Group I thaumarchaeote SCGC RSA3|TrEMBL
MIIVQISDLHVGSQFLEEKFNVLVNEVNELNPDVIVITGDLTNEGLMKEYEKCKSLLEKF
NTKKIIAISGNHDYRNTGYLLFKKFFPFQTVNELSDDVVLVTVGTARPDRNEGEVGYRQN
LWLERTMKKFKDKIKIVAMHHHLIAIPDTGSDQLTVVDAGDVLRTVLDSKVDVVLCGHKH
RPWAWNFGTLTVVNAGTATSERVRGLFENTYNILTIENKKVQVDLKIVGGKRVPIDEIVK
NYSQFHDELDNV
>J9ELJ5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Wuchereria bancrofti|TrEMBL
KYRVALEVLAYHSVCNKEEVKKLKSVKIDDEIKKLDRFEFNGLQLSELEKPVYAIYMFRK
LFKGKFNYDEDDLIRFVLTVRKNYRQVVYHNWLHGWTVAQAMYCLLRTTTIFNLKQSLAL
YIACLCHDLDHRGKNNAYMKSMSSPLASIYSTSVMEHHHFNQTVIILQQVGHNILKSFSS
EEYKEILGIIKHCILATDLEVFISNKREMEEILADGTFSWDNANHRFLMKAILMTGCDVI
AASKPWPVHTEVVKTIFEEFYEQGDEERKMDKIRLQ
>A0A3B0YPA3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MPQNRTDKRPLRIAQITDTHLFDSADGTLLGLNTRDCLDQVIKLAQQDTDFDLVVASGDL
AHDGSEAAYLQVREQLGQLGIPVYCLAGNHDEGRAIREHLHGNNFFCVRSELSGGWQLVF
LDSTIKNNEGGHLSTAELEALSQALDKHPDLPAMVWLHHQPVPMGSRWLDTMAVDNPDDF
FAVIDRHPQVRAIVWGHVHQTFEQKHNNVRLLSSPSTCLQFLPDSEDFAVDEIPPGYRWL
ELYPDGSLKTGVKRLADIPGHIDLSARGY
>B2IWK2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MTLPNPGSVLATLTELTQVNRTHALLRRVKDLSVNEFVCLLDFITAEFQQFLRAIELINN
EALETMLEKVLEAITLKIGQILQAEHTAIFLVDHDKGQLWSKVPQDNSQKFLEIRTPMTV
GIPGHVASTGQYLNISETYTHPLFSPELEKQMGYKIHNILCMPVTSSKNQTVAVVQLANK
TGNVPFNHDDEERFRDFAASIGIILESCQSFYVAARNQRGATALLRATQTLGQSLDLEAT
LQIVMEQARILMQADRSTLFLYRKEMSELWTKVAAADGTNLLEICIPANRGIAGYVASTG
QALNISDAYKDPRFDPSTDRKTGYVTRNILCLPVFNSANELIGVTQLINKQQNSFTASDE
EFMRAFNIQAGIALENARLFENVLLEKQYQKDILQSLSDAVISTDMAGRIVTINDAALEL
LGCPVKDTNTKSHKLLWEQNLIGRLVWEVVPIENLQMRLEDSLKTGAKHYVPEQTLMVGI
SQVKNAVNGSGTFSTQYSILAMCDRTNPNVFIPWNLPLTTESEFFSPDEVQTLERSTNLT
VNPLTNPEGGVRGGLVVLEDISQEKRMKTTMSRYLTPHVAEQVMALGEDALMVGERKDVT
ILFSDIRGYTTLTENIGAAEVLSLLNQYFETMVEAVFNYEGTLDKFIGDALMAVFGAPLP
LTENHAWRAVQSALDMRQRLEEFNQRRIIQAQPQIHIGIGISSGEVVSGNIGSRKRMDYT
VIGDSVNLSSRLEAVTKEYGCDIILSEFTYQMCSDRIWVRQLDKIRVKGKHQAVNIYELI
GDRNTPLDANTQEFLYHYHTGRAAYLSRNFSLAIACFKAAKYIQPKDQGVDIHLERARNY
LQNPPPESWDGIWTMLTK
>A0A6N3F1H1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium tertium|TrEMBL
MKKIKIISIVGVLILAILSIIWASKPRPISKNTKTVTATSNSDLSFAVLGDVHENIDHFQ
ETINDLYTINPVMDALILNGDVVDQGLDEEYRSVEKALEKNEDLLPKTIIKNIGNHEFFD
YKIETNSKEQVQGFINKYLEFAGEKKVYHDKWVNNYHFISLGSEDGNSETMNSVTAFIST
EQLEWFKEKLAEKYEKGKPIFVFLHQHLDYPNSSWVGVQQSEELKEILSQYPEVVLFSSH
THRDLTEDSVVLNKPFTIVNTGAVHYTIIPDSSSENGFIRDRSFIKGVYIEVNGNNVTIK
GRDIKEKQWIFSKDISK
>A9KH89|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Coxiella burnetii (strain Dugway 5J108-111)|TrEMBL
MEDNCIKIAQVSDLHLTSENCETSRGRYSNAMNVFSAISLSGQHDMIFITGDISDDYTEN
SYKQLLEMLKKLTCRVFVIPGNHDDVNLMNKIIPEKYLFSPETVTSFNTFDFLFVNTVVN
GEIHGLLTDQDLSLLQNHLENSGNKKKCIIMHHNPIPLNRKIYDKYMLLNYQDFLRIICL
YDNVKLVIFGHVHNDYTISYRQTLFSSAPATCYQIKKFESDIIIEEKYGYKNYFLFE
>A9KEE3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Coxiella burnetii (strain Dugway 5J108-111)|TrEMBL
MRRLFFVLFLYLFFDVALAAPAFQLIALGVHGGWSDGNLSTYLAAPLGSDQYVSLDAGTL
INGVEKAIAQGSFARLAVKTKGNLRNAIVENHIPVYLISHAHFDHIMGFVIAAPNLKEKQ
LLLARAETMRVLLRNVFNWQVWINSGNIGEKPRLGFQRFEELPLRRWISLPRTKLEVKAF
PLNHGKGYPSTAFLLKHKNDYLLYFGDTGADSIEHDNKIQQIWREIAPLIRRHQLHAILL
ECSYTNAQPNNQLFGHLKPELFLMELHKLAAQVSPHTSNALKGLVVFVTHIKPSLTMPDN
QVAKIIFQELKKGNSLGVRFILPRQGERYVF
>A0A1R4HXR8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Leucobacter sp. 7(1)|TrEMBL
MTSQHPPVEHFILHLSDTHFVGTDEKLHGVIDSDANLRRLFEDFARSQARPDAIVFTGDL
ADAGQEDAYRRLRAIVEPAAAAIGAEVIWVMGNHDTRTPFRQLLLDSDAGEESVDMVSDI
RGLRIVALDSTVPGAHHGEITEEQYAWLAEVLAEPAPHGTLIALHHPPVPSLIRGMEFVE
LADQQRFADAIAGTDVRGVLGGHLHFTTFSEIGGVPVSVASATCYTQDLNVEPGGMRGQD
GAQGFNLVHLYNDRVMHTVVPIGEFSTVYEVTAEQMRSFASMTVDEAAAAIAHNAGH
>A0A0H2M2J2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Variovorax paradoxus|TrEMBL
MTASNLLSASALPVQWAGELLHLLPEHAVWWPDGRVLFIADLHIGKAATYRALGQPVPGG
TTQENLARLDALIAAHGPQRIVFLGDFLHAAQARTPRVLAALAAWRAAHASIGMVLVRGN
HDSRAGDPPAALGIDVVDEPYLLGPFACCHHPQAHATHFVLAGHLHPVCRLHGPGRDSVR
LPCFASDAQQAVLPAFGEFTGGWLMERAPGRRFYAVGGESVWALPPSEQGV
>A0A0M8JIG6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sphingopyxis sp. C-1|TrEMBL
MLIAQITDIHIGFDPDNPAEYNRKRLDEVLDILIEGPNRPDLLLATGDITDRGDEDSYRR
LATAFSRCPFPVWPSVGNHDLRDNFHARFPGFDDGNGFVQYTIELPELRLVTVDTLEEGR
HGGAFCAQRAAWLEAELAKDPAKPTYIVMHHPPVESGIEWMNTDPDEPWVAVFTDVVRRH
PQVRGLICGHLHRSVTVAWEGRTVAICSSTAPQVSLDLRPIDENRPDDRPMIVAEDPAYA
LHRWNGRELVSFYDHAGAHTMLAKYDERLQPLVRELKAERPR
>A0A2G9TD40|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Teladorsagia circumcincta|TrEMBL
IPLVALENYLHALEQGYSKHNNPYHNVVHAADVTQSSHFMLSQTGLANSLGDLELLAVLF
GALIHDYEHTGHTNNFHIQSG
>A0A3S6H213|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Helicobacter pylori PMSS1|TrEMBL
MQVYHLSHIDLDGYACQLVSKQFFKNIQCYNANYGREVSARIYEILNAIAQSKESEFLIL
ISDLNLNLNEAEYLQDKIQEHRLQNKNIQIQLLDHHISGKEVAESFHWYFLDTNRCATKI
VYEFLKKHYALLEPKNTTWLEPLVEMVNSVDIWDTQGYGFELGKVCMRMINQSSELNRFM
FDDENRDYKLKLLEEVKNYLFLENAPVAYDNDLFRLKKIALGGDPNTETMDNISSNAQTH
LLSLKKHDCSVYYQDKKGFLSYSMGGISVLANLFLTQNPDFDFYMDVNAKGNVSLRANGN
CDVCELSQMCFNGGGHRNASGGKIDGFRESFNYRDIKEQIEEIFNNA
>A0A517VR61|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia aquarii|TrEMBL
MPIHLPTQNRRQFLITLGAGLVASQTGVYASETQQEIVYLLNDTHIGEKHPANSPVPSHL
RQVVSELVGLKRKPACVLINGDLALKDGQPGDYRHFAKLIRPLREAKIDTHLTLGNHDQR
DVFYEVMKEEQPESPPVKSRHISVVQTRYANFFLLDSLHKTMVTQGTLGKEQRTWLAKAL
DAHSEKPAIIVTHHNPRLGGNPVHFPGGLTDSVELWKLLVARPQVKAYIHGHIHHRGNAQ
HQGIHIFNTPATSYVANPDKSTTGWTIARLSPKGITLTTRTNDEEHAWNHQSKTLHWR
>A0A2P8ZP98|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Blattella germanica|TrEMBL
MSMYSNIPLWLVFSLLCRRLADEDDELSEVQPDAVPPEVREWLASTFTRQLATTRRKADE
KPKFRSVAHAIRAGIFVDRIYRRVSNTALMQFPPDVVRVLKTLDEWSFDVFALSDAASSQ
PVKYLGYDLLNRYGMIHKFKVPPVTLETFLSRIEEGYCRHKNPYHNNLHAADVAQTVHYM
LCQTGLMNWLTDLEIFATLVAALIHDYEHTGTTNNFHVIEEFREFRTLVIDMVLATDMSF
HFQQLKNMKNLLTLAEPSVDKSKALSLVLHCCDISHPAKRWDLHHRWTMLLLEEFFRQGD
KERELGLPFSPLCDRNNTLVAESQIGATSSPQRSQKYKIKKPWSTCLGENKKIWKEQAAK
GNKMLIQVNNFICVGVPYPT
>A0A1C5T8B1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Clostridium sp|TrEMBL
MYILHLSDIHYRREFGKGFRNANGDGYQNMLSAMQNPTVFLDECLDRVAGDRETVDLVVV
TGDLTEDGNAEDYRSLKHHIRERIGDVPLVVTLGNHDNKQSFREGWLKEGTDGERTAGSC
DSRPYHQVEWVDGTAVISFDTSAQGVPDGRLDEERLNWLRTALKEVGNHPAILVTHHHLL
CEQGQIPPLPESGRLLELIGDSGIFLILCGHTHHHYAGLAAGRPCHIADSLSFCGDNVGG
GKVRFQEKYGYNSYRIEEGMVRMSRSETFANGRILGTLTF
>B6ELX2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio salmonicida (strain LFI1238)|TrEMBL
MFKSKLVVFFTCLSVLSFTVQSSSFDTVTLGSKGGIQDGNLTAFLIKSDQDSNFVMLDAG
SVVNGLIVAEQKGAFKNIDLPDDSPYSKVGYLLNDKIKGYLISHGHLDHVAGLIISSPDD
SKKPIYGLEATNRDLMNNYFNWSAWPNFGNKGSGFKINKYNYVDLVPTTWNAISDTTMSI
MALPLSHSGGESTAFILKDQKGDVFAYFGDTGPDDVEKSSALKTVWTTLAPFVEQGKLKG
IIIEVSFTNKTPDKSLFGHLTPNWLIKELTVLENMNGKGSLKGLDVVISHIKYSLKNSED
PKVIIQKQLADANDLGVNFIFPEQGDSLTF
>B6ELX2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Aliivibrio salmonicida (strain LFI1238)|TrEMBL
MFKSKLVVFFTCLSVLSFTVQSSSFDTVTLGSKGGIQDGNLTAFLIKSDQDSNFVMLDAG
SVVNGLIVAEQKGAFKNIDLPDDSPYSKVGYLLNDKIKGYLISHGHLDHVAGLIISSPDD
SKKPIYGLEATNRDLMNNYFNWSAWPNFGNKGSGFKINKYNYVDLVPTTWNAISDTTMSI
MALPLSHSGGESTAFILKDQKGDVFAYFGDTGPDDVEKSSALKTVWTTLAPFVEQGKLKG
IIIEVSFTNKTPDKSLFGHLTPNWLIKELTVLENMNGKGSLKGLDVVISHIKYSLKNSED
PKVIIQKQLADANDLGVNFIFPEQGDSLTF
>G2FDQ1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|endosymbiont of Tevnia jerichonana|TrEMBL
MGTEPTNDSKLFDDLPDGAITLLQLSDSHIYADQDRCLVGINTQDSLDQVIALARQQLST
PDLLLATGDLVHDASAAGYQRIAERLSAFGCPVYCLPGNHDVPKVMQEHLNRPPLYCLPS
LQRGNWSIIFLDSTIPGKPGGHLDDAQLELLSETLNRHPKHHTLITMHHHPVPVGSAWMD
TMALVNPEPLFHLLEQHSQVRAVLFGHIHQEFDTKHRGIRLIGTPSTCIQFIAGQDKFGI
DSKPPGYRAMVLLESGEIRTEVRLLQALPLGLDLSSGGY
>A0A1U7M3P4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Tissierella creatinophila DSM 6911|TrEMBL
MKILFLHLTDIHCKDGSDLNNHKLEQMINSLNSLGDIDECILVASGDLAYSGAINEYKVV
RGFIGTILSKLGKKLDKYIKLLIVPGNHDISYGTSSRTSEDIIELFKNGKNIDDELEKDH
ALMKNFWDYANSKNCFKHNRSCDVKIIQFGNFTIQANLINTAPFSTKKMDNKELHYFPED
KLYSLLKKETVDLAITVMHHSTEWFRWDTKNNLEDTLLKNSEVVFQGHEHIAKGVQQIEN
NKNGTIISKGGEYSGRFTHESTFSAMIFDSTDFTIENTIFKWNKKESIFIKEDLFGPHKI
KKKNNEFEPNDDFIEQFYADNQNLADDVTDYFVFPELNTKYKAQSEIKKKILDEEGFFSV
LSEIKCINITGRNSSGKSALLKYLYKASLGRGFTPLYLGSDDYKSKKINKLLRDLFEEQY
SEESVDFNRYEQLDRDKKIVFVDDFNSINHIGSRDKLLEYLVNNVGYVILSSNEIFDVNL
IEPVKNALKYESDIENYIISDFYKDKREELIIKVCELNSPEICRDDIDNLIRVVDAFVLK
KFGLFNLTPDFIIQYIKFFLGQHAQERRGEGVFNLIFETNIRNSIIKNSHKSEVEDFMIS
LEEIAFYMHFNKTENISSTKIEEIINQYCKDYAIKIDIQRFMESSLKSKIIQSSSGSLNY
EFSNRNLLSYFIAKKINKLIERNGPDIEELHYILNNICFGINDTILLFLSYLRSNTKMVL
NLCKQVNKILDPFEELNFDKSNISFLKKAQLDNISAPNSTDRKVYKEHATERERHLQKQE
EEIRYVSIYDYDESEIERFPNNINRAIKYMEIISKSLVSQFSILNSTEKTEIIDCIYKIP
NKILYAILKKYDDNYDQIIEEIKGLLDVMEGSPDIEKEKIEKFFVSFSIALCLSLYDNIA
FNGSDRKTLGLLNEFEMDNSNYLIMNLMMIENGDTTDGFIENFKRLMDNSGDLFLKQLVQ
LVARKHIMTRDALNHSQRSKLLEGFPESSKKQILLSSFQSKKKAR
>A0A7W8YTM6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pedobacter cryoconitis|TrEMBL
MNKKLYFFLLLLSNLVFIHGYAQNQKSFKVIPLGTKGGLDESNLSAYLIAPIGSENFIAA
DAGTIRHGIDVAISNQLFKGPAGEVLKNNIKGYLVSHAHLDHIAGLIMNSPDDSKKNIYA
FPSVIEVLRDKYFTWKAWANFANEGEMPRLNKYTYVPLEAQVKKELTGTEMQVTAFPLSH
GPGYESTAFLIGHQESSLLYLGDTGADEIEKNTQLEKLWKQVAPLILKNQLKAIFIETSF
SDKQPEDQLFGHLTPRLLMVELTKLSKLTGVEALQKVSIVITHIKAWDKEEAYLVNELKQ
KNQLGLKLVFPEQGKYLEF
>M7NPI4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Paeniglutamicibacter gangotriensis Lz1y|TrEMBL
MSAASTTLIQLTDTHLLDDGALLRGSIDTWARTTEVLRAAARFAPDAVLVTGDIADRGAQ
VYSRAAALFEQTEHELGCPLVVVPGNHDPRGAVGADFNLKRLASGPGPADTVQMVGGLRI
IGLETHGFGEAAGYLSAGQLDWLRSVLEIPAPAGTVLAMHHPPIESLMESLAGRGLARPQ
ELAAVLQGTDVRGILCGHYHLPCSGTLGSIPVWVSPAVSYNHELFAPGTAGQGQDTSWLS
VITLSLGQLTATPVQMAIPAPLLTVAEAVPARHHVLI
>I4KXR1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas synxantha BG33R|TrEMBL
MPRVPTMNPDAALLVQLSDSHLFAEADGTLLGMNTRASLQRVIDLVHEQQPCIDLVLATG
DLSQDGTLASYQLFRDMTAPIGAPARWIPGNHDEPQVMAEAAVQSDLLEPVVDVGNWRIT
LLDSAVPGSVPGYLQDSQLQLLAQALSEAPSRHHLVCLHHHPVSIGCAWMEPIGLRNPEA
LFAVLDRFPQVKALLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEGFQVSEQAPGYRW
LRLYADGRLETGVERLRDFAFTVDYGSNGY
>A0A448T741|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serratia fonticola|TrEMBL
MESLFRLPVASGAKVRILQITDTHLFAGKHETLLGINTYASYHAVLDAVIAQQRECDLIV
ATGDLAQDHSQAAYRHFADGITRLPAPCVWLPGNHDFQPAMVDALAAAGISPSKQVLLGT
TGRCYCWIARCLAYRTAS
>A0A5C6FBN0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rubripirellula reticaptiva|TrEMBL
MSFHLIPSTRRQMLTATASVGAVAAMTLLGPFESQAAESGVESDPNFWALIADTHISEDA
SAVSRGVNMFDNFNRVIDSVLAETVRPVGAIINGDCAYLKGKPGDYANFKRCVDRLLAAG
MSVHATMGNHDDRGNFYDAMSGGKAGETLVEGKHVTVIETSHANLFLVDSLQQVDHVTGE
LGSAQLDWLNAALAARSGKLAIIVGHHNPQVSPVEPGKLLTGLADTAALFDTMDRHSNVK
AYVYGHTHDWKLTTTPGGTHLVNQPPSAYVFNPARPSGWTRLRLSPAAVQFQLVSVDTLH
PQHGEQLQLAYASKAGTTLP
>D8IW37|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Herbaspirillum seropedicae (strain SmR1)|TrEMBL
MHVEILGCSGGIGGNGMRTTSLLIDDDILIDAGTGVGDLTLERLQAIDHVFITHAHLDHI
ACLPLMIDSVGDMRPTPITMHATAATLEIIRKHIFNWHIWPDFSVIPSAEQPFLRFATIE
PGQTVALGQRSITALPAAHTVPAVGYQVKNERSGASLAFSGDTTVCPPLWQALNRIVQLR
YLIIEAAFANRERELALLSKHLCPALLLEELQHLQSRPEVLVTHAKPSQVQEIAAEIAAG
GTAHRPRMLEAGTILEL
>A0A1T0A0L1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moraxella caviae|TrEMBL
MNADFFPHILNSTQTHFTIAQISDLHLHDAPNSIAYERFLQLLSAAKQAKPDLLLLTGDL
ANDGNQAAYDWLFAELVKSQLPFVCLAGNHDVTIEKNAHLPFDERTFLPCAADARLASQH
KIRLQFHPENPKNTENPTHAWQLLLLNSALPARADGALSKQTLAWLDETLAQDSTPACIA
LHHHPLPVRSAWIDAHRLKNADDFWQIIRHHTHARLVLCGHVHQAQTLIAPSTHACTLLT
CPAASRQFLPKAHDFALDTAPIGLRIIRLTARDFTSEIWRVADGVISVE
>A0A109LFA7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas fluorescens|TrEMBL
MPSVSAVNPDAVLLVQLSDSHLFADADATLLGMNTRESLQRVVELVRTQQPAIDLILATG
DLSQDGTLASYQQFRDLTAPLGAPARWIPGNHDEPQVMAQAAMHSDLLEPVVDIGNWRIT
LLDSAVPGSVPGYLQDEQLQRLAQALSEAPDRHHLVCFHHHPVPIGCAWMEPIGLRNPEA
LFAVLERFPQTKALLWGHVHQEIDGERNGVRLLASPSTCIQFAPGSEDFQVSEQAPGYRW
LRLHGDGRLETGVERLVGFAFTVDYGSTGY
>A0A2N5ALV2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella variicola|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFID
SSHAGTSKGWLTDETIGWLEAQLFEGGDKPATVFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A0N4XY61|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nippostrongylus brasiliensis|TrEMBL
MYRDVSLKSIRSQVGMVEAPLSEVISLLRDAAGRVEGETAQLVKDAVKVLSSHELYAPSI
TRFRDSDRIATQYYDGLIRLHHPNRAHGEKRRVSADVKNALENDSEWCFDILQLEKVTEN
HALTQLGMKIFERWKVADALSCNEDILHRWLFTIEAHYHAGNAYHNATHAADVLQATSYF
LDSPSVAAHITENHAVAAILAATVHDLDHPGRGNAFLINTRQSLAVLYNDHSVLENHHVA
LAFQLTLQQNSNMNLVDVAEEAREGNSLTICNMLVKCADISNPTREWALCQRWAYRIVEE
YFDQTREEREKGLPVTMEVFERKTCNVPLTQCGFIGENFY
>A0A193SWH1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas cerasi|TrEMBL
MPSAALSSSVLLVQISDSHLFAEADEALLGMSTRDSLEKVVDQVLAEQPHIDLVVASGDI
SQDGSVESYEAFRRISGRIDAPARWFAGNHDELPQMEQVAQPNGLLDPVVDVGQWRVTLL
DSAVPGSVPGFLAATQLQLLEQSLSEAPERHHLICLHHHPVAIGCEWMAPIGLRNADALF
DVLDRFPQVRAILWGHVHQEFDQMRNGVRLLASPSTCIQFAPGSVDFKVDTAAPGYRWLR
LHDDGRLETAVSRVVGLEFEVDYGGTGY
>A0A517MI33|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseimaritima multifibrata|TrEMBL
MPLHMIPPTRRRFLQTALVGGAALFATQSALAADSKDNDEWWAFLSDPHIDADPKRGARG
IVMLDCLNQIIDEVLAQPTLPAGVIINGDCAFSRGLVGDYKTLSSALQRLVDADVPIHMT
MGNHDDRQPFYEAFAEQQIDNPLVDGKHVSILATPTTNLFLIDSLLEVNKVTGEIGQMQL
DWLAKSLDAHADKPAIVIGHHYLQFPPKGAQGAISGLKDSQQLVDLFNARPHVQAFVFGH
SHHWKVSETEEHLHLVNLPPCSYVFNPAHPHGWVKVKLDSEQLALELRTLDDSHPQQGEQ
HALSYALAAKAK
>A0A485GKA9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas aeruginosa|TrEMBL
MSRHSNTPDTDASVLLVQLSDSHLFAEDGARLLGMDTAYSLEKVVERVAREQPSIDLILA
TGDVSQDGSLNSYARFRRLSAPLAAPLRWFAGNHDEREPMQQATAGSDLLEQVVDVGNWR
VVLLDSSIPGAVPGYLEEDQLELLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRQAPGY
RWLRLHADGRLETGISRVDDIAFEVDYDTTGY
>A0A378FWL3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MSQQADLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFL
GDRWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQH
SLRNAGALDSALSAWPRVKHLLCGHIHQELDLDWNGGA
>A0A0B2VVQ6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxocara canis|TrEMBL
MGLYTCFVFQIPYQTLENYLAALEVGYSKHNNPYHNIVHAADVTQSSHFMLSQTGLANSL
SDLDLLAVIFGALIHDYEHTGHTNNFHIQSGSNFAMLYNDRSVLENHHVSACFRLLKDED
KNILERLTREEYRELRNVVIEIVLATDMSTHFVQIKTMKNMLSLPEGIDKNKALCLIVHA
CDISHASKPWHLHSRWTEGVLEEFFRQGDLEASMGLPYSPLCDRHTVHVADSQIGFIDFI
VEPTMVVCGELLTKMVEPLVSLPPSDSLFPPGANGDGREGGTSSAALSPLPDTRSSSSPS
SIRRLPLNYSGKLEIPNPWTNFMQENKIRWKERAAKEEEERKLANGNADAK
>A0A2G8Y9F5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii COUG|TrEMBL
AVIYNDVAVLENFHSCLTFRTLENKDCNIFACLDESSFRYIRQYVIECILATDMKQHFES
LSRFRIRRNSPEFNYVKNVEDRWFVARMCVKVADIGHSCVPWNQHFEWSSRVVEEFYLQG
DEERSRNMPVSPLCDRDKHADMAKSQGGFLEFVVKPLIKEIDEIDPFGRVRSDILSHIEY
NEKKWQELQESGTEVVLVSHTSAEAADRNTVTTYAVRKIAGISHQQSKTATSKPSAAFFA
PDQGLRSANSKMMLRTIGSMPDVIRKHLQEAQKEEGEGEEKAPAEAPALSQGASGGQVAP
VASGARKDSRDSQTSRRGDSAEERVLPRPRRSHGSGGSSLVGEKVKERVSFADSVVSLGR
RGQRGASTSTDGSGRLDTNLSLAFTASDSAAGLDSSRASDDNARRDKGELNATGSRTSTS
SSGGRSRELSLEEASHTDSGSSPRGLLSSSGLRVTFGDLSEEDDSEDADSDEYKSVKSER
ETSGASESHQSPAGPSQGAPPRLFETAVTMKNPEHHASRKQ
>A0A655ZEG3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio cholerae|TrEMBL
MKVSSQSEDSSIKLIQITDTHLFAAEDGSLLSVNTADSFAAVVAAIGEEQVEFDAILATG
DISQDHTPESYQRFVRGIQPLKKACYWLPGNHDYKPSMHSVLPTQQIQAVEHVLLGEHWQ
VVLLDSQVVGVPHGKLSEQQLQLLDNKLTEYPERHTLVLLHHHPLLVGSAWLDQHTLKES
ERFWDVVAKHSNVKAILCGHVHQDMDRIHLGARVXXXXXXXXXXXXXXAV
>A0A0H5P504|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nocardia farcinica|TrEMBL
MAVVLPGGVFGPVPISRVAEYPRPDHVLFHFSDTHLVAGDGDLYGDVDAERRLSQLLEHA
TASRIRPTAIVFTGDLADRGEPGAYDKLRALVEPFAEDLGAPVVWVMGNHDDRGTLRRHL
LDERSSGQPFDRVHMIDGLRLVVLDTSVPGHHYGEISDEQLAWLREVLAEPAPFGSILAM
HHPPVPCVLDLAVTVELRDQRRLADVLDGTDVRAILAGHVHFSTYATFAGIPVSVASSSC
YTQDLAVAEGGIRGRDGAQAFNFVHVYPDTVVHSVVPIDAGPTVGSPATPDEAAARLAAE
GIVIPPAARIPHVMRRRQSTPEADDETVR
>A0A0H5NHC4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nocardia farcinica|TrEMBL
MPEVTIVQLTDTHIRPPGERLHGVVDTYANLTHVLHQLRASHRAVDAIVLSGDLADNGAP
EAYRRLRDAVEPVAEELGARLIYVMGNHDDRGAFGAELLRSDAALRHPDTTHDQVVQVAG
LRIIALDSTIPQRHDGRLEPAQLAWLADQLREPAPHGTLLVLHHPPIPSPLPATEFLRLR
QPELLAEVLHGSDVRLVICGHNHLTATAALAGIPVWIGPALAYRLDPLAPVGRQRGLTGF
GYSRIDVLGTSMVATAIEATPAGIVYDRAEQDVLDQLAALAAEAR
>A0A1V4J187|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium chromiireducens|TrEMBL
MRKIKKVVISIILIIAGVAAVIYMNKPKPIDKSAASKVPDVDLAFAVLGDVHENIDSFQE
SINDLYKINPGMDALVLNGDTVDQGIEKQYDSVKKTINKNKDLLPKIIIKNIGNHEFFNY
DIEVNSPEQVQTFINRYLEFAEEDKVYHDTWVKDYHFISLGSEDGNSETMNSITASISEE
QQKWLKEKLAEKYQKGKPIFVFLHQPLNSGNGANSWVGVKQSDQVKEILSKYPEVILFSS
HTHRDLDENSVVLNQPFTMVHTGAVHYTIIPDQGSEGGRRREPYIKGLYIEVNGDKVVIQ
GRNIKDKQWIFTKEISKE
>A0A5E5QAS3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Gammaproteobacteria bacterium|TrEMBL
MKHFIQISDCHIDDNAQTMGINSHENLIKVVDKIVTLQSDALLISGDLTHNGTPYSYKKL
KEILSPIETDIFVIAGNHDDSDNLASEFGACLFDRIALDAWDIINIDSVQIGKISGFVTT
NALTALDQQLQHSNAKYNLIVLHHPVVAMNSEWDDALSLENPQDLFAVLDKYPKVQAVLF
GHAHESVEFDKNGLKIIACPSTATQFNDEQRIGFNYYTLFDDGRLDYETQWINS
>G8Q3W6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas ogarae (strain DSM 112162 / CECT 30235 / F113)|TrEMBL
MPSVSSLTTADAALLVQLSDSHLFAEADASLLGMNTRDSVRAVIDLVLKQQPDIDLMLAT
GDLSQDGTLESYAAFRQLTARIDAPARWIPGNHDEPQVMLQAAVKSTLLDPVVDIGNWRV
TMLDSAVPGSVPGFLAEEQLILLANALSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEVDRMREGVRLLASPSTCIQFEPGSEDFAVGSQAPGYR
WLRLLPDGQLETGVERVVGFAFTPDYGSNGY
>A0A1J5RJH4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|mine drainage metagenome|TrEMBL
MRIHVLSDLHIEVAAYQPQPVECDVVVLAGDIGNHVRGMEWGRHNWPDREILYVPGNHEF
YRLGRIETLREMRVRARELSVHLLDNDEVVIAGIRFLGSTLWTDFDLFGGELKKAAMAEG
KKYLNDFRLIRERFRMFGPARSAQLHKTSRAWLAAKLNEPFPGKTVVVTHHLPSARSVAD
RYKASLTSACFASHLDELMGASVLWIHGHTHDSFDYVLHGTRVVCNPRGYCRNPDKPENR
EFDPALVVEV
>A0A1J5RBQ9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|mine drainage metagenome|TrEMBL
MAIVVHLLSDLHLEFSQYQPHSSSDRADIVLAAGDVWHKDRGIRMLRAMWPDKEIVTVSG
NQEHYKATICPNMELMRAAADEVGIHFLENNEKILTIRGEKIRILGCTLWTNFLLYGLEK
RADCMVDAGQYLNDFRLIRNGSWNFSPKDSINLHNASVKWLESKLDEPFDGPTIVMTHHA
PSYKSVVKRFQGDLLSACFASNLDHLMDGSKVDLWCHGHMHDDLDYYINGTRVMCNPRGY
CRFEGGEENHSFNPALLISVEKGKVELVESAEDKAAERLVPMLSGRKRNELIWAIDHLQS
ALYWYPDGVVEYIDLRLITSDVRWFAEAIVQEKSWYLKTIPERIAVWALAVEDIDRLVNV
IVKRSRVTKRAAKRSPRVSAKEEAIAALNRLQIRTDINDKFKYYELAELPNYLRTEYWRT
RFGSTQPVVPGAVEPVYLWDYETWRERQLRKLKS
>A0A1C3HN09|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serratia marcescens|TrEMBL
MRIIQITDTHIYSEENKIGLKHLSNLKYIVDFIESNLDQINADLIMVTGDVSHDGGDASY
DKFFKTMSHVSLPVYVIPGNHDNKQGLRYASEKYDCGLNVNSFSNKDWRILSVDSVVENE
DYGFIKKKDLVGFENEVLASQSKKIAVFLHHHPIQVGTPIVDNCMLMNASEFLDVCQRLN
VTFIGSGHAHTLFQRKIGDTLVSVSPAACSQWKNGTKEVSFIDNSAFSVINLGEHVHVAP
WFI
>A0A6F9A2N7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Coregonus sp. 'balchen'|TrEMBL
MSSDCSKSLIKKINHLSPSSLSPSRRLVDTEDELSDIQSESVPSEVRDWLASTFTRQMGL
MRQTEEKPRFRSIVHAVQAGIFVERMYRRSSNLVGLSCPPTVIAVLKHVDKWSFDVFALN
EASGDHALKFIFYELLNRYDLISRFKIPISAVVSFVEALEEGYSKHNNPYHNLMHAADVT
QTVHHLLLKTGIMHWLTELEIFAMIFAAAVHDYEHTGTTNTFHIQTRSDTAILYNDRSVL
ESHHVSAAYRLLQDDGEINILCNLSNDDWRELRGLVVQMVLATDMSCHFQQVKHMKNFLQ
QPEGIDKPKALSLLLHTADISHPAKKWDLHHRWTASLLEEFFRQ
>A0A1E7X4K4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Duganella phyllosphaerae|TrEMBL
MRTIVHLSDLHFGRVDQQLLDPLRTLVASLAPDVLVVSGDLTQRAKTEEFIAARAFLDTL
PGPQIVVPGNHDIPLYNVASRFLTPLRRYLRYVTLDLTPEYVDDEIAVLGLNTARSLTIK
DGRVNPEQVALIRQRMSAVPKDVTRIVVTHHPFDLPQTFDKDDLVNRAPMAMRAFSECGV
DLLLAGHFHASSAGLSTDRYKLPGYAALVVQAGTATSTRGRGESNSFNVIRVHSDKIEVV
RYSWVDGTATFEPAQTEIFERIGEAWHTTAVA
>A0A1I9GDF3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Brugia malayi|TrEMBL
PRSIGSGDIYVEPSLSIFKDLGFVQRFRLQRQTLACFLLMVQKGYRDVPYHNWSHAFAVA
HFTYLLLRTETAHNALNELESFALFVASLCHDIDHRGTTNAFQVQSRTPLAQLYSSEGSV
LERHHFAQTISILNMEECNIFVSLNRH
>U6FIW3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactobacillus helveticus CIRM-BIA 101|TrEMBL
MRMAQRKKPAAIIVTGDITFNGERVSAEKFAEIFKPLKHTQVLVLPGNHDIFDGWAREFR
GKKQFYAGEISPMFWRSIFAKSYRQAFNTDDSSLAYSVQLNPQYFLILADSNIYGTEETT
AAPHTRGMIGKSQLKWIEKQLQYAEKINFVRFYLCIIICMLIILL
>A0A143QE50|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodococcus fascians|TrEMBL
MKSRMAEYPRPHHCLLHISDTHLVDGGGRLYGGVDSELRLEQVMTDVRNSGVRPDALVFT
GDLTDKGEAGAYEKLRALVEPVAEELGAQIVWAMGNHDDRATFRRTLLDAEPSGQSIDRV
HDVDGLRIVTLDTTVPGKHHGELADEQLAWLADTLATPAEFGTILAMHHPPVPTVLDLAV
LVELIDQPRLADVLRGSDVRSILAGHLHYSTTATFAGIPVSVASATCYTQDLNVPAGGLR
GRDGAQGYNLVHLYDDTVVHSVVPTGSYDTVGEAVSAEETAHRLDAAGVTIADSARRKLF
SDA
>A0A165VAM9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudovibrio sp. Ad26|TrEMBL
MIFAQLTDIHIKAGGKFAYNCVDTLYHLRQAVAHLNAFRPRLDFVVISGDLVDLGNADEY
ELFRQEIDQLEMPFYVIPGNHDHRDAMRDAFADHDYLTSEGALQFSIEKEGLRIIGLDTT
IPGKHDGHFDADKQAWLRDELEAHKDQPTLVFMHHPPFKTGIQHMDDIMLMRADEDFWPV
VTGQSQIRQIACGHVHRAIEVFKNGIPVSICPASGHQVTLDLDPHGEPGFVMDPPAVRIF
RWSEGELINHLSFIGDFGGQHPFFDKDGKLID
>A0A3R7YUJ4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii CAST|TrEMBL
MRLREHSLLLCVDAMSRDSPVASPAHSGVFGPSADAEVSEVFSLPSLSAVPGAASASSLS
RENSLVSSRRASPSVSPPAGSLLWRLVRRCGQGEGERENVERCRLRERREECGAARRGPP
ASAATSDCSCPSAGDRRRVQSRRRRARTFQGRSFCGNHVSTEAEREGETEGEEETEGEEG
REEYDSKRRGRLARRLGRRFVIAAAERGRKREGEETIVLRGNQGECWQEAQRTADSPDCS
SSSVCCFGGSCSTASQCCACMRLASVSCPSPRSSFSTFHCSLPAVSSASAAFVCPRESPG
SDSNSSPSCASSRGFSPSSPKATVSSSRPSSSSASPLRSSLSAPSGLFPVGSGCSSDVCV
SVPLPAMFRGCRVHSSAPSSRTEQGTALLTGAPPSANELEAASAMANPTNSSRFSRVKTV
SFATLSECGSSHISRRSDSASEPEAEREKPGLCSMRVARRESSPAARSPGRQSERRGTDS
SCTSLPQRSDRAGRDRV
>A0A5P9HB76|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Halomonas sp. THAF12|TrEMBL
MRLIQITDCHLHADPAARCRTGLPHRQLERVVAAAAGLRPDMVLLTGDISEDRTAASYAE
AERLLAPLDCPWFWLPGNHDDPGLMADCRPFLDAVDLDARRLLLLDTQRIGQEAGELGEA
RLAAFAARLAEDDRPTLVLMHHPPVAVGSAWMDALGLADAAAFWDVVADHAHVEAVLCGH
IHQAFAGRGPEAAGGVPVYGCPSTSDQFLPGAEDFAVDEASRPGFRVVDLSRGAFATWVE
RVEL
>A0A7K9E1T4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Baryphthengus martii|TrEMBL
MVKQLETGEVNVEELKRNLEYAASLLEAVYIDETRQMLDTEDELREMGSDAAVPSEVRDW
LAATFTQQARAKGRRAEEKPKFRSIVHAVQAGIFVERMFRRTYTAVGPSYSTSVLNCLKS
LDQWCFDVFALNRVTEEHSLRTIVFELFTRHNLNSRFKIPSTFLTTLLDALEAGYGKYRN
PYHNQVHAADVTQTVHCFLLRTGMLVRGILGILGILGGVHGAAAGVGVGALPDPCPVPSP
WSRELRALVIEMVLATDMSCHFQQVKSMKTSLQQLERIDKSKVLSLLLHAADISHPTKQW
SVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEPTFSVLTD
VAEKMVLPLAEDGTKAKGNPAACQQPSSQWRQASLDEHAELGEVKADLAGFRATWTKYIQ
ENKQKWKERAASG
>A0A1X6ZGF0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseovarius albus|TrEMBL
MSAKLSTRILWLSDLHFDLQNLVLGHDPIARLNAAIEFITQHYADAALCMITGDMVETAT
VENYTAVRTALDALPMPWLPMAGNHDKRTLFLQYMPLPDSAQSGFAQYTVDLPNLRLICL
DSLKTGADSGELCAERLRWLKGILERTDTPCAVALHHPPVPLDLPMLDPDRLEDSENLMQ
ILAQYPMVKHVFCGHVHRPVTGCFNGLPYTSIRSVLYQAPPPMPAWDWDSFNPAPEAPDL
GVIDIRSEGLNIQFTPFCSADHCVTPATT
>A0A1L3LFT8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sinorhizobium americanum CCGM7|TrEMBL
MKIVQISDTHLSPSKTHFNDNWEPVARWIETVGADLVVHTGDLTIDGADQEEDIVFSMEL
MRKLSVPVLIVPGNHDVGHLPGSDQPVDAARLDRWRRLVGPDYWVSDHGNWRLIGLNSLL
LGYGDEEEERQFQWLEQTLATRADRRVAIFAHKPLFVDEPLEGDTGYWSVKPQQRQRLYE
LMAENDVALHASGHLHWAWRGQHAGTDLLWAPPTSFIVDTLEREMPGERLVGAVLHHVEG
SIDSEIVAIPGLTRYVIDPVIEEIYPRHARKLAEAAQ
>A0A433E0T1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces sp. NP10|TrEMBL
MLVLNPFPLPLHLVTGNHDAPEALVGGFGGTRFLGGGRLTSYVVEYPAFTVVVLDSWVPG
SPGGRLGSGQVPWLGRALAERPGVPAFVCLHHPPVPVGIPFLDAMGLADGPALAKVVAAH
PRVVRVLAGHVHRPVTAPFAGSTVAVAPSTYRQSGLVLREGVPGYPDEPPGFLLHVRPGA
PAGAAWVTHTVLTSAPGVSR
>A0A1R4HWW0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Halomonas sp. JB380|TrEMBL
MGKSCLIAQISDPHIKAGGRLSYRQVDTAGALRQAIQTLNQLMPRPDLVLISGDLVDFGH
PDEYATFKQILAELTLPVYLIPGNHDDRDHLRTAFPEHDYLFQDAHYLQWVIDDYPVRLV
GLDSSVPGEPYGELSEESLCWLDKTLAEQPQTPTLVMLHHHPFISGIDHMDRQPLKQPHA
LAEIINKHAQVERVLCGHVHRTIQARFGNTLAISCPGVSHYVSLDLTPDSPSRFQLEPPG
YLLHQWSAEAGMVTHQGFIKQYPGPYPFYDANGLID
>A0A151ATH0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moorella mulderi DSM 14980|TrEMBL
MFRVLHLADLHLGYRPDLPAPVQEEVYRERNGVLQAAVDLALDPRRGISLVLIAGDLFDN
HRPEAPLVEETIRELGRLEAAGIQVVTVPGNHDEITYNDSVYRREANRWPGLLVTEPMPA
KVATLRLNGDTCHLVAMAYTGGVTRVDGPLKAFPPAEGEGVNLAVFHGSLDWDGGERSLP
LDGEALSAAGYDYIALGHIHRGGQRQLGRGLACYAGMVAGKGFADPGTGSWTIVTLGDGP
ALVEQVAAAVRPWRVVDVDVTAFHAPEELEAAIRELIDPGALVQVRLTGSIAFDLDLEGL
QARLGHLCSYLDLVNDTAGWAPELLESLAAEPTIRGLFVRRLQEKLAGAAGPGEAAVIRR
ALWRGLLALKGGCGPCRL
>A0A086KUF9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii GAB2-2007-GAL-DOM2|TrEMBL
MWFYSYLRHPNDVPSLCTHIRSSNIFLRLGPQYYLPEDERKSLFVRTCHLLYYLASLLFL
TTLTTYTAIKIPSSPSTTTELLSQLFPFNSIDDCNERLSCKVDCVLYAFPDLNCAKDDGS
LLTFGGNSYSSLYFYHYPGKDVPLQKEARTAWERCYQIMRETTGRLQFLQQDRETVERTH
TCFAGCKTNGAVTFTQKLTDGTPVVFDSGTDWLQMAPAGSLPQDTRPACNPSEPPSLLCV
EPTDECQHVTLRYQVCIGDTAFCFDIVRILITIALGVVWNVVLDAFVVWAMSIDDSDPQN
LGRVASKCGLQIIATAIIVSSFFCLVASMTRILSMDANIARHGTLWTSFVLVIIIDQLFS
FLFSVLIWYAMLRRCGRQLPDESRFQYKIHPSPVLVKLKKATRKIVNYNGFEMFFTMLLG
WMVVDLTCRMILCQFFFDETAFLNQADRILEVVDFIILILFIVEICLRIAADGLKIYFSD
PINCIDFFLVFFGFGIRIVDFFIQINKGIGNVLFIMRLVRLYRLHRPPTGSLAIGKKEVF
TSRVERIIAVLNKALEIEELTTREKDSLKWLIQTISSGKLYEMGSEEKKKTDSHVQAWIS
IISTQSQSANQMADDMENILLERVKQMTKAGDAETDMPAVLQLEYGIDVSLDHAIEGYLA
NNLITWNFDVFRFHVIAGRAALPKLFVRCLQHQEVCSLFNLKIENMLRFAMELEKTSFST
TPFHNSIRSAEVLQAMHLFLAFFDTQIKGFFNSREILAALLAAVVWDYQHPGFSSAFLIK
TQHAIAIRYNDRNVLEHHHVAAAFSLMQKLGENDPLLAFPEDQYIALRKIIIQLSQSGSR
SNQTACLSLLKTKLQQAEFPRSITEDKNIILCNLMNAANYSFLGRPLQLYLQWSQKYMEE
LFMQGDRELELDMPITKNCDRHTTSEAVVQLGLIDGWAIPIYTTLAQTVPKLNAIVVSHL
RRNRLHWLDEQQEEDKSKEKQTKVTPIKRYSKTKQGSTEATGNGELSKPEATTIEIADGT
AGVPELRANANPLSEVD
>A0A086KFF1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii GAB2-2007-GAL-DOM2|TrEMBL
MNASSKSMRIGFPNGSPGVGDPGMPSPVLPLCQTASHALGNARSQASEGRTDGASDRSIS
ELEKESCQRGHRLEAREASEILAAESAQEEHRSCARKPRASRVEVDTLAESPERPSQAYV
PTESLGLGPRRTVPLCSAGSSASAGSWISSGDSVREETRQIRGRDAANKCSTAELSVSVE
RSCGHHEGTDTATQCVAARPEALCAAFLPAPSPGVSVDSAAAAVGPHCAAEVPVGADRRR
RLFAAPFSALPQTDACSRGSATPPSLFSRQPFDTVRSSSSLRDGGNAWTRLLDGCSAHPT
SSSSSVSPPVLGSIRTLQQSLPSSDDDTTSARTDTSLTPAKQVWLLPLHGHSLSQSSSSS
FREFRVTLGSLTGFRSSDSRTSASGSERRRSKSRGKPQGRSGSLGRDNRRKSELSGRDES
LSWIARRWWTRDEDSRWSDSRVRGSVALRAESTSDSRCENNSCATWLCRVVRRLPVAPAQ
TFCDEDEKRYTEGVLRFSRRRTIPVAVAVVIVSFLYTVPFVLHALQEFVQTPSADRKVFV
FFSSRAPPRSPVAAGAAHDAQLDVSAADSALQDVGGKDAFFVVASLVFWLLSLASVLVFA
FFAVFGALFVRIEKILCVLTAVNFSALALAECFQALRISSCPPSLFPEQAAAEGGSDADR
CAQVHSGLTPELLIIQTFFLIVLDFAFCVRLRISQWLHLCAVSLLLSLAFVYSILLPLPA
YLIASLWGQAVIGGFVLGSLHLAALTLETERRRVFLHFEVAKARVAELQERAQTDKHHGK
VAVFGLIHTLKQMDACMNELQNLAPEAADVLFQLDALRVQCLDIATSSENFYAVNMNALP
TDVRDLLQLETRNAFDGTTFRDTQVLLRDSLSPRKGVLLDLSLGPACGGVSRERRASCSA
AVSSTSSRESDRREAIARDPDLTETERRDAERRGMERKATDDRQKKARFLVVPQLVEHEL
LCHVGILWSLDLFKLDKECNGNALLHVGYQLLAPLLAAGYLTCSREVVLDFLYSLQCLYI
DTPYHNQLHAASVAHLAFSICHFLDLFAPLENAPGDAAASQPVFAQYLSLAIAALGHDAG
HPGRSNAFLVQTSSTLSVVYNDRSILENYHACLTFYTLSHRKSNIFRGKTVTQYRDVRKK
AIELILSTDMSLHFEFLTRVAARRENPDFNFVDREEDRALVLSLAIKVADLGHCALDWEA
HTLWSARLKEEFLAQGDEELRLGLPVSPLCDRTQQGQLARSQANFIEFLFLPLAQHLAAV
APDDRFEATVVTRARQNISMWEGAQDEVDQASAK
>A0A0Q0JKH7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudoalteromonas sp. P1-26|TrEMBL
MAWFSNAYHFDKTALKVAHITDCHLSKDTTGEYFNVNTAAYFGRCLQVISELDVDCVVFG
GDLTQDHSTESYQLFAKLIADSALSCPVFWLPGNHDELAEYEKLTSPQILNNKRITFLGG
QLLLANSKGPTPAGWVTQTHLDELSQAVGQVPSVVFCHHNPLPIQAYLDKHMLENGPQFL
NTCVNTEQCVGVFHGHVHHGYTQTYRNLSVYATPASSIQFTKHTMAWLQEDLGPAFRLID
LNIDEQQNLLLSTDVVWLNE
>A0A378ZUR8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pannonibacter phragmitetus|TrEMBL
MEQYPRPMTLIVQITDLHLRPRGLACYRVSDTNMLAARAFRAIAALPQKPDAVVITGDLT
DGADEREYALLRQLCRQMPCPVYVMPGNHDLTAAMRSELADFPGVGDAPAGDKLHYAVTI
GGLRLVVLDSSVAGKPYGRLGGDQIAWLDQTLAADHTPTLVALHHPPRVTGIAHMDVIGL
ADTEALAAILSRHHHVERLICGHVHRTIIARFAGTVMTLCPSTAHACVLDFAPDAPAEFV
MEPPAFFVHRLDPEAGLSSHLHYVEAYPGPYPFFADKGVSWPGGK
>H2Z2W1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ciona savignyi|TrEMBL
EHIRRNIEYAIAVMESRYVNRVVEIPDDEVPATLSGEGPVPPEIKRWLVQTFTSRRADVR
GRKESETRRSLRSVVHAVQAGMFVERMFRKTSVGVQNLPPEVQEHFKNIDSWSYDVFELD
RISDGNSLKFVFYELLNKYDLIRKFKIPLKSLFAYSARLQRGYRKYNNRYHNPIHAADVA
QSLNCLLVSSGFVHWLSDLEMFSMIMAAVVHDLEHSGTTNTFHTNTRSPLAQMYNDKSVL
ENHHISSAFRLLNEEDCDILVNFSKDDYPSKEARTLMIDMVLATDMSQHFGQVKKLQSNL
QHPESLEKSRAMCLMIHSADINHPSKQWELHCRWTERLVVEFFEQGDQERKLGLPLSPLC
DRHTTMVAQSQIGFMDYVIKPTYDVLFDIFRNVNGPVVRDAILSLRRAS
>A0A226MC95|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Colinus virginianus|TrEMBL
MVKQLETGEVNVEELKKNLEYTASLLEAVYIDETRQMLDTEDELREMRSDAVPSEVRDWL
AATFTQQARAKGRRAEEKPKFRSIVHAVQAGIFVERQMLDTEDELREMRSDAVPSEVRDW
LAATFTQQARAKGRRAEEKPKFRSIVHAVQAGIFVERMFRRTYTAVGPTYSTSVLNCLKS
VDLWCFDVFALHRVTEEHSLRTIVYELFTRHNLSSRFKIPAAFLTALLDALETGYGKYRN
PYHNQAHAADVTQTVHCFLLRTGMLHYLTEIEVLAIIFAAAIHDYEHTGTTNSFHIQTK
>A0A378YAR8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pandoraea pnomenusa|TrEMBL
MLLCQITDLHVTRPGALACGRVDTALALRRAIAAINHLTPRPDAVIATGDLIDTAHPSEY
EVLRECLAELTMPLYLVVGNHDHREALRDAFPEHVYLRTGYEFLQYRVDLGPTTVLALDT
QDPPGASGHLCESRLSWLDAQLHACAGRPTIIAMHHPPFETGIEFMDGYGLSSAGREGFA
RVTSCHGHIERVICGHLHRSIQAQVPGAPNVMASTCVSTAHQISLGLAPGAPETISLEPP
GFALHLWQPGAGVRTHHAFVGPFDGPYRFDGASVS
>A0A137SAI6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Marinobacter excellens LAMA 842|TrEMBL
MTIAHTAHPLKVLQLTDPHLMASADGALLGVNTRDSLAAVIDEVLRNHGQPDLILATGDL
TQDASSEAYRYFGEQLKAFNCPSLWIAGNHDDSDLLASIAAEFQAEQKQLVQGGWHFVML
DSSVHGKVFGELSQPELAFLDESLSQQPELPTMVCLHHHPVDIGSDWMEKIGLKNRDAFW
QVIDRHPQVKIVLWGHIHQDLQQQRNSVQLLATPSTCIQFATGSSKFAVEPLAPGYRWFE
LEASGQYSTEVCRANGFEFDLDEKSTGY
>A0A0F0CIZ7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium sp. FS41|TrEMBL
MSLYAIGDLHLSFTVDKPMSIYGREWENHVAKIEKNWKKRIREQDTVVLTGDHSWGRNMD
ECRADLDFIASLPGQKILLRGNHDMFWDAKKTCQLNDLYQGSLSFLQNNYYMYGEYALVG
TKGYCYEGRDTPEQYEKLVKRELERLRISFELAVAGGFRKFIMFLHYPPTSIGEMESVFT
RTAEEYGASQVVYSHCHGAARYQDSFQGEVNGIEYSLVSSDYLKFKPGLILE
>A0A1S8L2M9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium felsineum DSM 794|TrEMBL
MIHTKRVFKTNMILFCEFAFFLNILNGSSIFKSQKLKFNNEGKFKIVQFTDLHQNDSINL
KTVHFMEKVIDSEKPDFVMLTGDNIDGRYCMNITYKKAIESIVKPMEERKIPWAVVLGNH
DTESIDVKRKDMVKEYTKYQYNMNKLTEGNEFNLLVMNSKDSLPIFNMYMLDSGDYSDDG
GYGCIELSQVNWYKETSSGLRKKYKHIIPAIMFFHIPLIQYNEAFEKNNLSGERREKICY
QGKDTGLLKEIQKQDDVKAIFVGHDHTNDFIGKVGEVFLGYGRCTGYDAYDDSNYERGAR
IILLNEKDTSKFKTWETLDKNLK
>A0A8J5BWS7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Yarrowia sp. B02|TrEMBL
MTFQVVVLGSSGGPIDRGTCSYLVRGSPGGEPVQQEAFIAVDAGCFLAGIINVLEKQVLL
SPQEYQHELLAESIRPNQASQRSWNVAYPPFDASSLPYGGPTANAAHILSLVSTICITHP
HLDHISGVIMNSAAFSPQQTKRLAGLPRVIQALKDHVFNGVIWPNLTNEGVDAVHLVQLL
RLSEHLRSPDLASGLTVTPYAVSHGHILRPAHQTHPSPCHHQPFKPSFSIRPSEPSSEPH
RGSRRMPSSVIPPDSVIEMRRQSLMLEKRQLRASIASVNSHLHSPTSPSLVPHRKSSGGT
SSASSVGSVSPSSYPTSNPTSHPTPGPPLGASLASYDSTAFFIHDSKTNRVLLMWGDVEP
DSISYTPRNYLVWRKAAEYMQQGLLAGVFIECSFANPHDDALLFGHFSPRHLIAELKYFA
SMVEGSEEDFHAMVGWEDLNETNEMDVENMDEEVSIPVPQRLPQHTQTHGADLHLQGLPV
VITHVKEDIYNEDPENDPRKVVLEDIIGLAKIENIGCDFIVATPGLSLHL
>A0A3P8C5P9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Heligmosomoides polygyrus|TrEMBL
MGSWGIEHGSLCDTIVTTVDGQKFDTKDLDNDRGMAMVADWSLPIFEIAEKHAKTVLSRL
TYTVFKQADLFRIFKVSPIKFFNFFHALERGYWDIPYHNRVHAADVLHGCYYLTCHPVRP
LIGPTTSPDSLLPPPLTLAAPISASMSTLELMALYTAAAMHDYDHPGRTNAFLVAAEDKK
AILYNDRSVLENHHAAESWRLLQLPENNFIETLDPAETKRFRYLVLEYILATDLKQHFEI
IMTFNEKSSEMELQNESDRLLMAKMVIKMADINSPTKPYSLHRQWTDRICQEFYEQGDEE
RRRGMPITPYMDREDAQVAKLQDSFIAHVVSPLALAMNEAGLLPILPGLVEPEMMINLKH
NHQKWLQEIDNTSGEPGKPMTNCLGKGLHSYSVQ
>A0A379UV78|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salmonella enterica I|TrEMBL
MLIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWL
DQHSLRNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFT
LDTIAPGWRTLELRANGVLETEVHRLQDTRFRPIPLRKDTDVYASLFARIQQFPSLGKSV
PAKKLAGGASSAC
>A0A0F0M1D4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium ginsengisoli|TrEMBL
MPGVVVSDGLRVTRTDEDGRFRIDQVRGPVFITRPAGWRVDRWYVGASAIDPVFTLSPAP
VQLPVRFAHLTDTHLGTGAGYPQPAEIGTGERLSQAFREIAAAHPGLEAFVVTGDLTDRG
LPEEFAAFVAATATTELAVYAIPGNHDHLVPDPTDLVSRNGYAIHSGEPRHYEDYLGPRW
YSFDLPGLHVVAVDWFTHELGLDHETQDTWLRADLEMLATGTPWIMLCHDQPWRSILDGL
PSAPIATFSGHRHTSRVVASGPTLHVNTPPAMFGGVDNSPATYRIVVWDGERITTGSHQT
YPPQSDTRSGWARTTQALWSTSTPAIGQRTPFIVADGRVLVPLALDDEARGALAAYDACS
GKPLWQASLDAPLRSAPAGAGTAAIISSTVSGTTWAHDPSTGEMLWQRPTSDPLRRFGFY
PPTLVDGLVLVGDQAALRALDQSTGEIVWERSDIAAYQIFITLSAPVVDRSGANGSLTTV
LWAGFPEPSTPVRLDPKTGETIANSNEVVAEGLFDVLTSGAGLPIRTPSVDPATGDLIAT
GLTNVFRRSASGSAIRWSYPTSVPWNPVGVNLGSHGVLVVDAGGAVAMLDPVSGEQLWRT
EIAADSDECFLTYRRSPHPLFAQATTVGDRLLIPALDGDIVTLDARTGDELGRFATGVPI
LAPLVVHDGTAVALHRDGLLAAYPLATLAGERL
>A0A378AWL6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae subsp. ozaenae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFID
SSHAGTSKGWLTDETISWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYR
>A0A1X7BV24|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseovarius aestuarii|TrEMBL
MTTILQISDTHIVRPGQLVSGRLDTAASLEKLVKRVSANKSQFGKIDAILVSGDVSDDGT
AESYAFFKSLMAPLEAPLFVIPGNHDLREPMRRTFSEQGYLPSAGKLNWHQQIGDIDVIG
LDTLVEGAGGGEIDAATLDFLETAITANKSRPVLLALHHPPFPSGIAFMDRIGLEGIGKL
AKVLSGVDTEIRVVCGHIHNTMVANVGGKTALSSPSSCSCFEFDVAGDTPVGFMDQTDGF
MLHRWQDGFQSTRIPVETGSGPYPF
>A0A8F8UHA2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nonomuraea coxensis DSM 45129|TrEMBL
MIVIAHLSDIHLGATPESAARARAVMRHLDALPADLDAVLVTGDIADHGTADEYEQARKL
LASRHPVLIGPGNHDVREEFRRVLLSEPDPGPGPVNQVLRTPRAIYAMCDSSIPRQNPGH
LDEETLDWLEGVLAGSDRPVFVAFHHPPVPLHAPLIDGIMLRPSPRLEELARHPNVAAVL
VGHAHTAAATTFAGRPLLVAPGVVSTLTLPWEGGTTWETCLDYALPPSLAFHVLDDEGRT
TTHYRVVTAP
>A0A484YSI2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli|TrEMBL
MEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGH
IHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAARLAYSRVTC
>A0A379KK56|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas putida|TrEMBL
MPHPDPSQAPVCVVQLTDAHLFADPAGTLLGLRTRDSLRHVIAQVRREQPCIDLLLCTGD
LSQDGSAASYQAFRDLTGDFAVPARWLPGNHDEARVMAEVAPELVQAVTDIGAWRIIMLN
SAVQGATHGLLEPAQLSLLDDALVSAGGRHCLVCCHHQPVDIGCAWIAPIGLRNADELLR
RLEGYPQVKALLWGHIHQEWDELRGGLRLLATPSTCIQFAACSEDFKVSEEQPGYRWLRL
HADGRLETGVQRATDFEVKLDFDSPGY
>A0A1V5UWF2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lentisphaerae bacterium ADurb.Bin242|TrEMBL
MKIYIFPLLFFLSLQTVFSAEPWRGPLTIAHISDVHTTSREREGNILKIIEEVNANPEID
LVVVSGDWGGDAYPEEFVLAKKWFDAIKKEKITVPGNHETQWGYGSGTRFADTFGNDRFA
ISVKGIPVFGLNTSPPLQFIKSHIRSDDLQWLEGKLKEHASAPFVIVVSHYGPNGNELGN
WFDLPEILRKNGIGKALILSGHWHRFMLCNWNGYPGIVGRAVAENKKKKQHGPGYVILNI
SGDGAVTASEKLLGKPPLAPEFTFKLGDAEWLAKTVNSGRNLRNARWAIKTPPEAKAVIE
TNETIFGGVAFSAGRFFYATHAGELVARDSGRHDFPVSWKVRPGGRLYGTPAVIGKNVIV
GATAPARVCGYDIADGKLKWSVEANAPLLNSGVVYDGKLYVGLGRDQFAAIDPDTGTILW
KVPCGNGEFQALPAVTDTLVVTGVWDEHAYALDRKTGKMLWKWRSPRSGLRYSPGNSTPA
PGKDCIIIGTASTGVVLDAETGQCRFPFKGRESHGISVDGTTGYTRQLNGRLTAFSLSAP
KYAEKFSVPYAKQDSNPAPIREYDGRIWLGTTDGEILVFSSDSGRILYRGKCGFSTVISI
DRAPDGMIWVILAEGKIMLFPSGVEKHVSSQPHL
>A0A378LUK2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Legionella wadsworthii|TrEMBL
MRIIHISDLHFGMHNPLIIESFLKDMKELKPDIIIISGDLTQRAHSHQYKQFSDFLQHIN
AQTLIIPGNHDIPFYNAYYRFLYPFKKYKKYISEKLETNFSNEEVSILGVNSATPYLAKN
GILSQKTLRHIQNHFSEKSKKLNILFFHHNLHYFSGMHHPLKNAEEFLTYLKDSPIHIVC
TGHLHYANVTSITKNQGDQCLLLHGGSAFCFRTKDGKNSYYSINTSHSRCSIDWRVFVDN
SFLSHKIYEFDLIL
>C0QCF5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Desulforapulum autotrophicum (strain ATCC 43914 / DSM 3382 / VKM B-1955 / HRM2)|TrEMBL
MLSFLEASDTSIDDVGAHLKKMVEIGIALSAEKNIDTLFDMIVEEARALAMADSGTLYIL
DRDRNVLSFKILQNNSLGLHLKRTENAEILLPDVDLYHGESPNYENASSFAALQGKILNI
PDVYASTTFDFTGPMKYDSVTGYRSQSMLVIPMKNHENEVIGVLQLLNAQEVESGRVVPF
GDRCVSLVEALASQAAVALTNRQLIQEIKKLFYSFIETIAGAIDEKSPNTGDHIKRVVKI
TMALAMAVNESNQGLFKEHFFDDEEMEELRLSAWMHDVGKITTPEYVMDKSTRLESKFDR
IHLIETRFSLIAEIVEKQYLEKQVKLLQSRETSSDIFLELEKARKENLSSIHEDLAFIKT
CHRAEFVNDKMIHRLNKIAEKQYIVSGKIQPFLDPWELENLSIQKGSLNETERHIIENHA
TMTLKMLSCLPFPKNLSRVTDFAASHHERLNGTGYPRKLKGDALPLQARIIAIADIFEAL
SARDRPYRKRMEISHIFEIMGKMKENGHIDPDLFDLFVRSDIGKKVKL
>A0A5B9TTL7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sulfurospirillum multivorans|TrEMBL
MNYTLHHLSHTDLDGYSCQMVSAHYFDSIRFYNSNYGKEINECFNQILATIQSSELQKHV
ILITDLNLTMDQAKEFESKVSICDKEIMMFVLDHHKTGQECADAFEWYYLDSSRCATKIT
YDFFSALYGKDEKLSHYVDVVNAVDIWLEDKPEFELGKVCMGLVSGAREVNKIMFPEENS
KYIFALLNKAQEYFTCKEAHIALDDAIHGIKKSFFTTSKNDTLSNLVSAYNVILLTQNRD
KMQISYKEYKGILTYNIGNVSVIGNDFLTANPDLDFFMDITSKKTISLRSNGKVDVSKMA
AHIANGGGHHNASGGLLSNFKDAFIYDTIKSQVMSIITNKG
>A0A8J4KBA4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Eudyptula minor|TrEMBL
RLRSLVKQLERGEASVVDLKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDSVPSEV
RDWLASTFTRQMGMMLKRTEEKPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIGV
LKNVDKWSFDVFALNDASGDHALKFIFYELLTRYDLINRFKIPISALVSFVEALEVGYSK
HKNPYHNLMHAADVTQTVHYLLFKTGVAVRSKAVPPKDNSFHLSEEDKSHALDGDADLHP
ISAAKPAELAYIETYRELKEFRALVIEMVLATDMSCHFQQIKAMKNALQQPEGIDKPKAL
SLLLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDKEAELGLPFSPLCDRKSTMVAQSQI
GFIDFIVEPTFTVLTDMTEKIVTPLIDEASRSGMSGFRRSSLNSISPSEVKRSSVKSTGS
EGSASLNCSILTVDFKCFKATWTEVVQQNREKWKAQATKEEKAKKEAEENAHQGTDEKKT
DEKDEKKPAEDATAAKTENSKEPNPGENKSTDSKKNHVNGTRQTGVNKHEASQGENAPRT
DKGTDCELKEDNKLDKKDQSSVGDESKKRDGKGNILLHFRMLGMVTIIVLPLSPPAIKPQ
LRHLRRPTNSSGDYFPAFHKKSEEHPVRCKLLDQRGRMKKIQHISQSWNRK
>A0A1W1DNW8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MNQSHDLIQISDCHIDDQAESMGVNTHTNLVSVVKAVTKHNCDTLLITGDLTHNGTLNSY
QVLQRMLMPIESKIVVMSGNHDQIENLNQVFSEQLISKFSLGNWEIITIDSTQPSKTSGY
VTKQALDQLDQDLQNSVAKYNIVALHHPIVSMQSDWDDSLSLENADELFNVMNKYPKIKA
VLWGHAHQASEFNNGDVVLISCPSTALQFDNETRIGFNHYRLHDDGKLEYNTQWI
>A0A1E8EWM9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium acetireducens DSM 10703|TrEMBL
MALFAISDLHLALNEDKPMDIFGNNWIEHDKKIKKNWLKKITKEDTVLIAGDISWSMKIN
EGMEDLNWIHKLPGKKIISKGNHDYWWGSIIKLNSLYDDMKFIQNNFYNYEDYAICGTRG
WPIKDNSSEHDKKIMSREIIRLKLSLDEAKKNNFNKYIVMMHYPPVNDRFEESEFTKIFK
EYGVEKVIYGHIHGPALKNVFQGKIDNIEYILTSCDYINFNPIRII
>A0A1E8F0N5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium acetireducens DSM 10703|TrEMBL
MISITKNKKTTIKLIIILITIIILFFSSEVNVLKEYTKNLVNRYIVNIINKVEKYSLPRY
SLKNLEEISSQVLSRKKNNFIIFEFITDSHYDETSGFRDKAIKHFREVKEMSRLIGSDFV
IHGGDIIDGYDKKNKSIMYLDKVLGELCKNNQCPTFYAVGNHDDNSYYNVRNTPQSHHNV
ISKREFYNITIGKYIKGIIVDEKNPEGMYYYKDFPNKKLRIIVLNTNDIPEIYHENGKPK
YNGILQYGISNEQLNWVANKALDFSNKEDKKEWKTIFFSHVSINKKINYDKSIPNGDIMM
KVIESFKYGKKYKSNKTKGDFGQYVNVDFSSQGSMDVIAVINGHVHMDNSDKVNGIMYIS
TLNSVPIQISPYLAPKRYIKTFVENAFDIFSIDTNNRKIYIDRYGAGSDRVFDY
>A0A7Z8Z9V2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Raoultella terrigena|TrEMBL
MIIAQISDIHAGPDNSNLSRFDSALKWLDAVEPDALVLTGDLIDNSWFEGYESIYSRLDI
RRFPTFILPGNADNKSLMRRVWGERFWSVTPFAEGLHFVADMGELRLIGLDSTIQGSSEG
AVGNHLAWLEKSLSYEDDAPSMLFLHHHIIQSGIPAMDHIMCKDHAQLGEFLQNSSRQPI
AIATGHVHRPIAGFFSGIPAYICGSICPANPLWFGTEIVPPVNDPPSLMIHRFINHALVS
HHVSI
>A0A091KHY0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Colius striatus|TrEMBL
LFSRLRSLVKQLERGEASVVDLKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDSVP
SEVRDWLASTFTRQMGMMLKKTEEKPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYPPAV
IGVLKNVDKWSFDVFALNDASGDHALKFIFYELLTRYDLINRFKIPISALVSFVEALEVG
YSKHKNPYHNLMHAADVTQTVHYLLFKTGVAHWLTELEIFAMIFAAAIHDYEHTGTTNNF
HIQTRSDSAILYNDRSVLENHHVSAAYRLLQDDEEMNILSNLSKDDWR
>A0A0C5VKI7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gynuella sunshinyii YC6258|TrEMBL
MSQKTPFQLIQITDPHLHAGEEGTLLGLQTQKSLDLVLDKIREEQPVIDALIATGDIAQD
SSLQAYQRFKTILEGFGVTIRWCPGNHDNKNTMNRAAEKSELIEKFIVTDFWVILLLDSS
VPHKVYGRFGHDQFELVNQVAGKYPDKHILIAFHHHPLPMGSHWIDQQQIKNGSELLTTV
RKYPNIKALLWGHVHQERDEVIDGLRFISTPSTCVQFEPHSEDFSIDKTGPGYRWLKLYD
DGSIETAVSRVQNVEFEIDYSVKGY
>A0A137S2Y9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moritella sp. JT01|TrEMBL
MIHIISDCHLGNTENETNLIKALMKIGDDCKFLFVMGDIYTSPSIEKYNNFKSILNEYVP
NAKVYAIAGNHDDINLMKKSFSGSNIFIKEKVNIDGMTYLFIDSSHKPINSIMMLGSGRV
SNKDLSKIKKESRKKEVTILIHHPILKVSNSKWFNEIGIENVDDVINKLNKNCVNIICGH
GHDFNHNKHSTFQQTMSPSTAYGFDLTLDEFMRTNRTGALILEYKNQKSTFQYVKTY
>A0A6N3G719|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Paraprevotella clara|TrEMBL
MSRIYNSVVGLLCGMGILSSCEIIEYHPYDTRIEGETGLTEKNIRLIEDKMRGRREFRFA
MISDTQRRYDETKEVVNIINNRGDIDFVLHGGDVADFGETKEFLWARDFLNKLRVPYVCL
LGNHDCLGTGFDVYLKVFGEDNFAFTVGNVRFICLNTNALEYDYSHPVPDFNFMEDELRN
MSAGIEKTIVAMHVPPGDGEFNNNVGRAFEHYVTSFPHVQFCLFGHIHRWAEEEFFEDGV
VYYGCTTVGKRGYYVITIKEEGYEIERCDF
>A0A2G9TJX5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Teladorsagia circumcincta|TrEMBL
VMKNDEFKFQEVFSDLEVMAAIFAGAIHDVDHPGFTNQYLINSNNELAIMYNDESVLEQH
HLAVAFKLLQDSNCDFLCSLSKKQRLQFRKIVIDM
>A9WNR5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Renibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235)|TrEMBL
MSTSNSYETLSILHLSDTHVLAKGLHSNVVDTRQNLLEALRALVPVEELDLVVVSGDVSD
DGTAESYRMVQELVENFASHRGARAIYTMGNHDGRPGFWEVLGNGHPDSPAEQDGGQLPV
YGSSVLGGFRIISLDTSVPGRTHGYLDRGQLDWLTEELGSASEAGTVLVLHHPPVEPVTP
LHDGIELQNPEDLLEVLHGSDVRLILSGHYHHGLVDSVLLGDQLIPVLVAPGIVNVNDVL
ASEGHERALRSSGAQLHTLFASAPTAAAARVRSLPLNLGVVEELFDLGPEELAEISARIS
ARPDEGSDG
>A0A1Q8KNJ5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudonocardia sp. Ae707_Ps1|TrEMBL
MITVVQLSDLHLGVPGNRERAVRAVAGARALGADLLLVTGDVADHGDPAEYAEAAELLGG
AAVLPVPGNHDDRDAMGTVLGPVGDRVHRAGGVNVVLLDSLVPGAPEGALSAGAVDLLAD
TARDPAPLLVALHHPPVPVGHPFMDGIRLRDAEPFAAVLAARTEPALVVCGHVHRPVATT
VGGHPLVVAPSVGPAIRFPGEPGEEFLLPDSVPGGALHVLGDGPPRTRFLAWP
>A0A120G4R8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas fluorescens|TrEMBL
MPSVSAVNPDAVLLVQLSDSHLFADADATLLGMNTRESLQRVVELVRAQQPAIDLILATG
DLSQDGTLASYQQFRDLTAPLGAPARWIPGNHDEPQVMAQAAMHSDLLEPVVDIGNWRIT
LLDSAVPGSVPGYLQDEQLQRLAQALSEAPDRHHLVCFHHHPVPIGCAWMEPIGLRNPEA
LFAVLERFPQTKALLWGHVHQEIDGERNGVRLLASPSTCIQFAPGSEGFQVSEQAPGYRW
LRLHGDGRLETGVERLVGFAFTVDYGSNGY
>A0A086QGK3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii VAND|TrEMBL
MNASPKSMRIGFPNGSPGVGDPGMPSPVLPLCQTASHALGNARSQASEGRTDGASDRSIS
ELEKESCQRGHRLEAREASEILAAESAQEEHRSCARKPRASRVEVDTLAESPERPSQAYV
PTESLGLGPRRTVPLCSAGSSASAGSWISSGDSVREETRQIRGRDAANKCSTAELSVSVE
RSCGHHEGTDTATQCVAARPEALCAAFLPAPSPGVSVDSAAAAVGPHCAAEVPVGADRRR
RLFAAPFSALPQTDACSRGSATPPSLFSRQPFDTVRSSSSLRDGGNAWTRLLDGCSAHPT
SSSSSVSPPVLGSIRTLQQSLPSSDDDTTSARTDTSLTPAKQVWLLPLHGHSLSQSSSSS
FREFRVTLGSLTGFRSSDSRTSASGSERRRSKSRGKPQGRSGSLGRDNRRKSELSGRDES
LSWIARRWWTRDEDSRWSDSRVRGSVALRAESTSDSRCENNSCATWLCRVVRRLPVAPAQ
TFCDEDEKRYTEGVLRFSRRRTIPVAVAVVIVSFLYTVPFVLHALQEFVQTPSADRKVFV
FFSSRAPPRSPVAAGAAHDAQLDVSAADSALQDVGGKDAFFVVASLVFWLLSLASVLVFA
FFAVFGALFVRIEKILCVLTAVNFSALALAECFQALRISSCPPSLFPEQAAAEGGSDADR
CAQVHSGLTPELLIIQTFFLIVLDFAFCVRLRISQWLHLCAVSLLLSLAFVYSILLPLPA
YLIASLWGQAVIGGFVLGSLHLAALTLETERRRVFLHFEVAKARVAELQERAQTDKHHGK
VAVFGLIHTLKQMDACMNELQNLAPEVADVLFQLDALRVQCLDIATSSENFYAVNMNALP
TDVRDLLQLETRNAFDGTTFRDTQVLLRDSLSPRKGVLLDLSLGPACGGVSRERRASCSA
AVSSTSSRESDRREAIARDPDLTETERRDAERRGMERKATDDRQKKARFLVVPQLVEHEL
LCHVGILWSLDLFKLDKECNGNALLHVGYQLLAPLLAAGYLTCSREVVLDFLYSLQCLYI
DTPYHNQLHAASVAHLAFSICHFLDLFAPLENAPGDAAASQPVFAQYLSLAIAALGHDAG
HPGRSNAFLVQTSSTLSVVYNDRSILENYHACLTFYTLSHRKSNIFRGKTVTQYRDVRKK
AIELILSTDMSLHFEFLTRVAARRENPDFNFVDREEDRALVLSLAIKVADLGHCALDWEA
HTLWSARLKEEFLAQGDEELRLGLPVSPLCDRTQQGQLARSQANFIEFLFLPLAQHLAAV
APDDRFEATVVTRARQNISMWEGAQDEVDQASAK
>A0A3G7WTI5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas orientalis|TrEMBL
MPSVSAMNPDAALLVQLSDSHLFAEADVTLLGMNTRESLQRVIDLVREQQPPVDLLLATG
DLSQDGTLESYQHFRDMTAPIGAPARWLPGNHDEPQIMANAAVHSDLLEPVVDVGNWRIT
LLDSAVPGSVPGYLQDQQLQLLVQALSEAPNRHHLVCLHHHPVSIGCAWMEPIGLRNPDA
LFAVLDRFPQVKAVLWGHVHQEIDGERNGVRLLASPSTCIQFAPGSDDFQVSDQAPGYRW
LRLHADGRLETGVERVKDFAFTVDYGSNGY
>A0A8B7JZA3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Apteryx mantelli mantelli|TrEMBL
LRYMVKQLETGEVNLEELKRNLEYTASLLEAVYIDETRQILDTEDELQEMRSDAVPSEVR
DWLASTFTQQARAKGRRSEEKPKFRSIVHAMSPGIHIPRLPYRMFRRTYTAVGPSYSASV
LNCLKSLDLWCFDVFALNRVTEDHALRTIVFELFTRHNLNSRFKIPTVFLMTLLDALEAG
YGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHYLTEIEVLAIVFAAAIHDYEHTGTTNSF
HIQTKSDCAILYNDRSVLENHHISAVFRMMQDDEMNIFVNLTKDEFAELRALVIEMVLAT
DMSCHFQQVKSMKTSLQQLERIDKSKVLSLLLHAADISHPTKQWTVHSRWTKALMEEFFR
QGDKEAELGLPFSPLCDRTSTLVAQSQIGEWRRGPIPIPVPVPIPHAMHGPWGWLGALR
>A0A1U7MJ10|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sporomusa sphaeroides DSM 2875|TrEMBL
MAGYRIRDGILIFLLAAVLAVLPVPLAGAVADAYTAQHVTLTWTDRASVTQTITWKTESS
WPVGKIMYAEKADSNVFTAKATVVTATSRPLPADGSGLVVHVAALTGLKPDTTYMYLLGD
GDSWSRPYWFTTAPANTAAFRFLVFGDSQSDRYESWGRLVRQAYQANPQAAFLTVVGDLV
DVGADYGQWQEWFDAAEAVISNVTVMPLTGNHETYTPVWGERTMPVLFTAQFKLPANGPD
GLQGLVYSFDYGDAHFVILDSQEREEARFIPDMLARQQAWLDADLAATAKRWKIVLLHKT
PYPVKSGRSNEPVKAAFVPLFDKHRVDVVISGHDHVYARTYPLTGDKITAGGTIYVTAGR
SGAKAYQYVTPNELHEFFHNPFEEPNYLVVEVGQDKLSVKTVSQSGQQIDSWQRMKERTK
EKIAS
>A0A0X1U8R6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Anaerotignum propionicum DSM 1682|TrEMBL
MKKKILSLLLASSMMISLGMLPTGCSSDNSASNNVEALWDGGNTRNKIVAISDIHLGIED
KYSETLKNRPILIEFLQRLQKTKDVRELVIDGDFLDEWFLPVYYPSYTDQRQFYKDAIAN
NQGVIDELNNVIDSGIKLVYVPGNHDMTLEADVLQEAIPKLVQARDAQGLGTYYTGDRNE
IAIEHGHRYDVFSAPDTVTNAELCGNANTILPAGYFYARYAATWVLEGRPKVEKDIPVVT
KVPDQSDVDQYGAYIYYSLLKDISTRMTPNENLDEKIFDMHISGFDDAYSYLDFYPTQQA
DGTISAPVLFRNIQRTWQERQILNKVKVTNSFTEAVAGTVNWDYYAAQAKAQYLDNPNEN
VDVVVFGHTHVPMYCDTGNGKYYLNDGTWIDHNTDYPDATRTFAVITTGDETTAAIYSYS
EDGSITDITSSVSKTDEKNTANSLENVAFDYKAVENYGDDAKQARYVEVSGLKDNTVQEK
LNKELKDFCLSPTLSSESDTTYDIMPVFEVVGGDLLSIRVYNTAYTAGAAYPVNSIQTQL
FSLTTGDKNAGNIWDFIKDKNAFKQLVLDGKLGMTAAGVEGEIPKDLKSEAYKKLSESID
TSEFAKQFYFGDGGNLNVWCEGKNHATGDYWLFDIPVTELENIASDRLLPIIEAIKKLSN
>A0A0N5D4C0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thelazia callipaeda|TrEMBL
LFQVLLTLRDAIGRVDDETQQLLRDAVKVLSSSELYAPTITRFGNNDRIATGYYDGLIRL
HHLPRSRKRSVVDAFKDKRTTASEHRRVSADVIFERWKVNEALKCSMELISRWLSTIEAH
YHATNPYHNATHAADVLQATSYFLESPSVAHYVQEMHATAALIAAAVHDLDHPGRGNAFL
INTQQPLALLYNDQSVLENHHVALAFQLTLQSTNNINIFAGITREEFAALRQATVEMVLA
TDMSRHFEYLAKFQQAVSNLKENEENESNISLIVCRMLIKCADIGNPTRSWALCEKWAMR
IVEEYFDQTTEEREKGLPLTMALFDRNVCNVPLTQCGFIDMFARETFTSWSEFADIPILL
TQLEKNYEKWREQTSTWDPSRNTHLREERCHS
>A5CN72|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382)|TrEMBL
MHALPPGSLRLVHLSDTHLLRDGGLHQGVVDTGAALERVLVEADRVPEVRLLVGSGDLSE
DGTAESYALLRERLVPWTSSRGAALVLTPGNHDVRSAFRLVLGDGHGAPGTDDGRDPAAV
PPVDGVTIVDGWRIATLDTSVPGKGYGALREQQLDGLRELLATPAEHGTVLVLHHPPVPA
PTTLHESLALQGPERLAEIVRGSDVRVILSGHYHHHIVGSLAGVPVLVAPGVANETDVAA
EPGTERIVRGSGFLVVDVRPDGRVTSVVVRAHAEDDGDEVALLDAGLVQRIIADSGAPAA
P
>A0A484T667|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|plant metagenome|TrEMBL
MKFIHLTDTHLVADGGELYGTNPKQRLRQAIAHLLARQPDAEAVVVTGDLTHHGHAQAYA
HLRECLSALTLPVYPILGNHDSRVVFKEYFPGVAQDEHGFIQYSVDFGSHLALFLDTNEP
GVHWGVYCETRAAWLRARLAETDRPVLLFMHHPFFPIGIPSMDFLSLRDPAPLLAAIAGH
EARIRHVFFGHIHRPICGQYRGMGYSTLRGTNHQVALDLHGSAQCIIGSHEQPQYAVVQV
DAEQLLIHVEDYLDCDRQFLLHEMRYGAAGLK
>V5VIX7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acinetobacter baumannii|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIQQILKQHPEADAIIHT
GDLAQAPTPITYKRYINFMQTLGLPFFQTLGNHDNVDHFPLHNENHQQPVVVGLGNWRVI
MLNSAVKGKVDGHLSSEQLENLANLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFQNVKALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLNNDGSFETKVFRLENFKTRINTDISGY
>A0A377WG64|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALREPPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFID
SSHAGTSKGWLTDETISWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A168TDF9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFID
SSRAGTSKGWLTDETIGWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A183VDW6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxocara canis|TrEMBL
MPISGVFVEGRNRGLLKTFEIPPGALVTYLLHLEHHYRDNPYHNQIHGGDVAQSTNVLIS
CPSLTGVFSELEVLAAIFASAVHDVDHPGFTNQYLINSSEISI
>A0A5C2HJR4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|[Arcobacter] porcinus|TrEMBL
MRLFHISHTDLDGYACQFLTNKVFSKNTFYNANYGLEVKQALKQALLDIEKHKDEKILFI
ISDLNLTPQESAELDKNIDELKEFGCDITLQLLDHHITGKKSSEKYDWYFLDDKRCATKI
VFDYLKDNFDAKIDEYKELVDTINAVDIWLENEVENFEFGKVLMSSIIKAREINSILFAS
LDREYKFYILDKAKDYLNFEDRHIVLDNDMHKIKKDYLKENKDDTLDNLSAKYLVKSLDN
IKDELTIVYNGQKGLMTYCLGSISIPANSFLRANSDYDFFIDINKKGNASFRADGKLDVS
QLAMKLANGGGHINASGCKFEDFVDSIYIQDIKKYIQNKLDNLK
>A0A0H4X507|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bordetella hinzii|TrEMBL
MLIAQITDLHIRMPGQKAYRIVETDRYLPPAIAALNALDPAPDAVIISGDLTDFGRPAEY
RYLRDMLAALRMPYYLMPGNHDSREQLRACFPEHDYLRQDDEFAQYTVEHLPLRLIMLDT
IVPMQSHGMLCERRLAWLEARLMEAPGRPTLIAMHHPPFQTGIAHMDKIGLLQGADALET
LVRRHANIERIICGHLHRSIFQRFGATVASTCPSPAHQVALDLRPEGPAAFNLEPPAYHL
HHWREGQLLTHHAYIGEYPGPYPFHENGELIDD
>A0A183D570|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gongylonema pulchrum|TrEMBL
MLFPAGRNNLHSFLLKQRCHFQIAPEDLLRLTVGDIPATTSYDQDFDHFDFPPRSIGTGD
TYVEAALSIFEDLGFIQRFRLQRHTLARFLLMVQKGYRDVPYHNWSHAFAVAHFAYLLLK
TDTARGALNELESLALYVASLCHDIDHRGTTNAFQVQSVSFVLILSSRYGHISIFRIGFS
SPKSVFFSSQVHKM
>A8JDI4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chlamydomonas reinhardtii|TrEMBL
LAGSGEWQYDTWALAEASGGHALSVMGFYLMQREGLVTTFKLQPIRLARLLRALEDGYPA
SNPYHNATHAADVLRTLSVLLRGARLTAHYAHGLGLLASYFAAIIHDHGHPGLTNDFLVA
TSHPLALRYNDRSPLESHHAASAFTLLSERPDLDPFDQMAKEQRTALRKQVIDMVLATDM
KQHFSLLTQFEALNKARKAGLSGGERADDADDRLLALQIALKAADIGHLAGELPVHCRWL
GVLEEEFFRQGDQERGRGLPISPLFDRAKQGVSKSQVGFFDFVALPLVRALSD
>A8JGY5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chlamydomonas reinhardtii|TrEMBL
MPSTDLSTDAGYPNNPYHNATHAADVVRTTHVLAHAACLTAHHLDTLGLLALYFAAVIHD
FGHPGLTGDFLVATSHPLALRYNDRSPLENHHASAAFTLMAERPELDAFEGLSREQRIAF
RKQVVELVMGTDMKQHFGLLSQFTNAVS
>A8JFA6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chlamydomonas reinhardtii|TrEMBL
MHGVLHMPLHLCGVTPRSRPRSVLGFSSAGPLQQAWRVVKVYPSTIIFPALLLGLCLGVG
VWGITYVARLQERATRERAEMAAADAALWIHQQLSTAIAPALLAAAVVKYNPQWSAAEPL
FQGLAPALLGQASNNSIRALQLQPSGVIRSVYPSKGNENVVGLNLFASEANREGALKAVR
DRVMTLSGPTNLLQGFYGITVRQPIFLPGVAANATLGQQDPLPNPACGELCNYNSSTGLF
WGFASVVMDWDAVTADPGSKLRGLQQLGFRYTVAVTGTPGGSRVVAASDTSPPEHAVQAT
IQLPNAQWEVLVSPDSGWNADWRQHQMLLEALLPKELIHDLREEHTASLAACPRMNMGET
PADLLLDMMCSLLEGYAPDLRDVVFIRTALLRNMDLYTPLNVKKQIKGANLDAEVAQALM
QQLVGGTGHQLSTLVPYRTGHSTGGGTAASGAGTGPPTVGVRLHAEQHGPGAGAGHTGHG
AALSAGSLHEFALHAGGDNALPLAREDGVLSLGTSPALTGRGTGLATASGLPGSSPPTGA
CAISFGGLRRGGGGADPEAPAGPSSLGAVGGGGGGGGWGSLWRSPARVSSGLAQEPSPLG
VSVSRLAGNSARGMVLSGGSNSPATHGAGGGGGCGGGVVEASGQSESAWSGGGGGASKRI
STPSRMALFNIVSAGSVAAAAIDSGNGSTHPGAAGSGPASQCVGGEGGGSATPSPRLRER
ECGRSDSSPQPYTVTAQGVQLSASPGATPPLFGSAARRGTGPGAVLGLAGGAAAAAAAVA
AAASEDVVLQVAAPPLGVAAALANPTPAYLPVVPNPIPVVNIVEQAEKLLARVDDWHFDM
LEVAKATNGHALSVTGFFILQRSGLISRFKLNPVVLARFLRCVESGYVNTPYHNSTHAAD
VLQMLHVIIHNAQLHVHYLDELGLLAMYFAAVIHDFGHPGLTGDFLVNTSDQLALRYNDR
SPLENHHCAAAFTLMRRPEFDLLAPLSAGERSSFRKQVIELVLATDMKQHFSILSHFNTV
HRLAAYSQQQQAQAQPATATGPPAATGADGHSKPLSIIKNPSEVREVAAAVGELTVPKPL
DDTERSLSLQVALKCADISNLGRELECYKRWVALLEEEMFLQGDKERELGISISPLCDRT
KVGVSKSQTGFFDFVALPLVHAMSSAFPGAARMMRHFLANYNHWKAVAPAAAPTPPAAAH
KADSETKPAVAAAELAPSSGRPTLAGAVVEVPAALASAPTALAPMTKAMAKLRSMGSRRL
VAAEPPAAADAAANGHAASKADA
>A0A1Y5TC82|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseovarius litorisediminis|TrEMBL
MTKIIQISDPHIVPFGQLAYGRVDTATPLAECVNTINRMLPVIGPVDMAIVTGDLTDFGT
AEEYQRFRDIMAPLEIPYRAIPGNHDNCDVMRSGFSDQEWMPEAGPVNWICEFADIALIG
LDSSVAGKSYGHLSDTTITYLQKHLDALQGKPVIVATHHPPFLTGKQKMDIQNLRESSVF
KDILSAYQGELKLICGHVHRNIVTLFGDVICQIAPGTSHAVTMDQRVDAPNCLTIEPGGF
LLHETRGNLVTHHIPIGQFDGPWLFYPDDK
>A0A120JVP7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Halomonas chromatireducens|TrEMBL
MRIVQITDCHLHADPRARSRAGFPLRQLEAVVNAAIGEHPDLVLVTGDISQDETAASYEL
AHGLLSRLDCPWFWLAGNHDQPQLMEPVKAIQREVDLGGWRLLTVDTSVPGQAHGEIGET
RLAELVEQLVADDRPTLLAMHHPPLGLGSEWLDAIGLKDRDALWQTLADFPQVRMILCGH
IHQALASRRQGVAVYGTPSTTDQFLPGSADFAIDEASRPGYRIVDLTDGEWLTWVERVDL
>A0A1Y5SGV5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oceanibacterium hippocampi|TrEMBL
MLIAQISDLHVLEPGELQFGQFDTNAALGRAVDTIRALNPRPDIVLATGDLTDHGTISEY
EMLAEILTPLTMPFYLLPGNHDLAPFIKSAFPDHDYLPDRGRLNYVIDDHPVRLVGLDTA
VPGEIGGSLGEEGLAFLDGTLAAAPDRPTVVFMHHPPFLTGIAGMDRYNCADGDAMAAIV
ARNPQVERVLCGHCHRPIQTRWAGTLASVCPSVAPPIEFNLVPDSGVRLTFEPAAIQLHL
WRPEIGVVSHMVYAEDFGEPLMVLPPSNGEA
>A0A157S8T7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bordetella ansorpii|TrEMBL
MSAAHVTPIDEQPALLIQLTDMHLMDEPHAEMLGVDTEASLKAVLRQAMREMPDAQLVLA
TGDVAQDGSRGAYRRLRGLLGQLGTTVRCLPGNHDDAAAMHAVLPDWTTPITDVGAWRVV
MLDSTVRGSDAGHLDDRQLDLLDQAAATADDRHILVALHHNPVQMDSDRHDTMMVDNPMA
LFQRLADIPQARVVLWGHVHRQFDRRRHNLRLLASPSTCFQFAVHNGRHTLDGAAPGYRW
LKLYRDGSLATGVRRLHPATWHALCNAAQPRAA
>A0A2X4YJF4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella oxytoca|TrEMBL
MLLAQISDTHFRSRGQKLYGFIDVNAANADVVSQLNALQERPDAVVVSGDIVNCGRPEEY
EVARQILGSLNYPLYLIPGNHDDKALFLEYLHPLCPQLGHDAQNMHYAVDDFATRLLFID
SSRAGTSKGWLTEETIKWLEAQLFDGGDKPATVFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQAIISTIPGTVHQVPYFYEDTRPYYDLSPASCLMH
RQVDEQWVSYQHPLTHYAGPWMYDENISCPTEDC
>A0A0K3BGN6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Kibdelosporangium sp. MJ126-NF4|TrEMBL
MAHVSDIHIDSEQRSIERATRVFDYLNGLPGPIDAILVTGDLADHGLAEEYGTVAKLFDS
SQTLLHCPGNHDSRGPYREVLLGQRASDGPINQVHRVGEAVFAMCDSSIPGRPDGYLADE
TLTWLESVLLDAGDAPVFVCFHHPPVVLHALFVDSIKQSGEERLAALISRYPNVVGVLCG
HAHTGAASTFAGLPLLVAPGVVSTVMLPWETDEIADLTMPPSIAFHVLDDNRRLTTHYRV
VSPRL
>A0A6P6NH48|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Carassius auratus|TrEMBL
MDLMRMRLRCLVKQLERGEASVVDLKKNLEYAASVLESVYIEETRRLVDTEDELSDIQSD
SVPSEVRDWLASTFTRQMGLMLRRSEEKPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYP
PSVITALKHVDTWSFDVFTLNDASGDHALKFIFYELLTRYDIINRFKIPVSALVSFVEAL
EVGYGKHRNPYHNLIHAADVTQTVHYLLLKTGMVHWLTELEIFAMLFAAAVHDYEHTGTT
NNFHIQTRSDTAILYNDRAVQENHHVSAAYRLLQEDDEMNILFNLSKDDWRELRALVVEM
VLATDMSCHFQQIKAMKNFLQQPEAIDKPKALSLLLHTADISHPAKNWNMHHRWTTSLLE
EFFRQVSVPRQFL
>A7SGA1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nematostella vectensis|TrEMBL
EIDENLENELDSVNEEVREWIATTFARGPGAARRKSMVRRHTFRGVVHAVKASLYVNKML
KNATERYKMHVPENVQKAFEWTFDVFALSESCEGHPLRYIGYEVLHRRDMLRNFKIHAMT
LDRFLQDVETGYKRHSNPYHNDCHAADVTHTVHYFLECMGVSKYLSDLEVFGLLLSAIIH
DLEHTGTTNAFHINSRSDLALLYNDRSVLENHHVSCAFRILQDDEKNILSGLNLEQYADV
RSLMIDTVLATDMSSHFEQLRLMKVALVAGSPIENREVVQLLLHVADISNPTKDWTIHRQ
WTTKIMEEFFTQGDMEIELGLDVSPLCDRSTTLIPESQIGFIDFIVSPALEVCSEVLE
>A0A0D1EDM3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Jannaschia aquimarina|TrEMBL
MLIAQLTDLHVLADGAPAYGRVDTLGHLRRAVDHLNALPLDGVIITGDLVEDSSADSYAT
LRPELDRLAAPWWPIPGNHDGPAFWDVFDDRMTDPAREIGHVVDLPGLRLVLLDTRVEGD
PFGRVDAARAGWLAEALDADLPTLLAMHHPPIRTGIAHMDRIGLEDLDALTAALQPRPPH
AILCGHAHRTIQGRLGGVPVLVAPSSADAVALHLETDAPPAFALEPPGVLLHLMDGAELV
THLSHIGPYPEPRAAHETDQGSAHGA
>A0A518ADM9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia panareensis|TrEMBL
MPVHLPAQNRRQFLFTLGAGFLTCSAGAFAKDAQQSDIIYLLNDTHIGEKHPENSPVPSH
LRKVVSELVNLEQKPACVLINGDLALRDGQPGDYRHFAKLIRPLREAKIDTHLTLGNHDE
RDVFYTVMQEEQPETPPVKSKHISVVQTQYANFFLLDSLHKTMVTQGTLGAEQRTWLANA
LDAHADKPAIIMTHHNPRLGGDPNHFPGGLTDSVELWEILAPRKQVKAYIHGHIHDRGNA
EHKGIHIINTPATSYVANPKQSTTGWTVAKLSPEGITLTTRTSDDQHPWNHQSKTLTWR
>A0A486UJV0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRESPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFID
SSHAGTSKGWLTDETISWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A6N7BY73|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Psychrobacter nivimaris|TrEMBL
MPNYPANKLSTSDQTINILQITDLHLSTPVFVDESNTYSDDVTCQRSFEAVLQQALSEDI
RCDLIIVTGDLVNRVKSSIYDHIFTVLQATQIPFACIAGNHDVTDENGKDLPFFQRELVA
QPADSRLLSRHVIETDFWQLLLLDSSISGKVAGEITPTDINWLCERLSTCNKPALIALHH
HIVPVDSDWIDTHMAENTESFWEHMAPFEQLQVVISGHTHQEQVRLRQGVTVYSTPSTCY
QFKPYEDDFSYDEHALPGYRWLQLANNGTVASWVERLDT
>A0A2G8Y6M6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii COUG|TrEMBL
MHRLLDWDFHVLALPPASAVLVTRDLLTQFALKANMDIPGEILMAFSVAIYKNYRPNPYH
NFYHALNVTQVLCLLLALPDVAAQFSPIDYLVLSVAALGHDLGHPGANNLFMTRFDCWPS
RIYQNVSVLENYHAASLFQILRHPAFNVFCSVSPTNFAPIRKRIISAILWTDMAKHFDVV
AKLQAKIQGEMVLAEGIIVTLTKPYLEGLLLHAADISNPMMDFELCRDWAFRACDEFYQQ
NKMEEMGGFPPSMPSFEHFDEYNVAQCQVGFIDAICKPLFNSLALMFPAQLGDRATQLQK
NRCVPLIIFPT
>F8UHT5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured microorganism|TrEMBL
MSRSIQKLLELTTLHEIGVVLSSTLDLDELLDENPTQAVTTHLSCDRAMILLVEERAGRR
VLASGHITGGTPEMVALTKGLEVSLEEPYSFLAKIVLSGKPIVVREMQQVTDVQAREYLA
GLQTRAFVAVPLLTQGKPVGYLGLDNAVTGRPIPETIQDLLSIIGAQIAAAIDRARVHQT
LERRVEERTAALAMATHRAEKAAVAITQADQ
>A0A3M2R9K3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Marinobacter litoralis|TrEMBL
MTNSDLKRPLRVLQLTDPHLTAQSDGALLGVNTRASLAAVIDEVLKVHGQPDLVLATGDI
SQDASAEAYRYFGEQLQVFQCPSLWIAGNHDDTPLMNAVAAEFQADQRQWVQGGWHFVML
DSSVHGKVFGELSEEELAHLDSALSEQPELPTMVCLHHHPVDIGSDWMEKIGLKTREGFW
QIIDKHPQVKAVLWGHIHQELHQHRNDVQLLATPSTCIQFTAGASDFSVEPRAPGYRWIE
LDPSGNIATEVRRASQFEFELDENSTGY
>B3PCJ6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cellvibrio japonicus (strain Ueda107)|TrEMBL
MRLIQITDCHLGPLQSESLLGLNTDQSLEDVLQLIRENEPDFDLLLCTGDIASAGHLECY
KRFSDIVRRYFSQPVGWLPGNHDSSDIMASSSLQSLAEARLMQQGNWLIVLLDSSVPGQV
YGQLAASELDFLDNMLSRHPDKHVIVSLHHQLVPVGSAWIDQYIVRNADAFFAVLDAHPH
VKLVTWGHVHQEFTSRHKQIALYATPSTCVQFKPHCENFAVDTLMPGYRWFELNEDGSFA
TGVERVTGKQYVIDYKSAGY
>A0A447LJE4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Atlantibacter hermannii|TrEMBL
MADACWRRLLPASSSNPICANFTIDTIAPGWRWLELHPDGTLTTEVERLEGTQFNPDTAS
EGY
>A0A086PN38|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii MAS|TrEMBL
RTITPMFDRRKHADFPKGQEGFLRFIIIPLYEEIAAVDTTDVVQTCCLQNAVANSERWRQ
LQSSPEEFEAIDAKHQAIICVLKDRLEWRVQKNIAPTQRLLRASCAENQVRGSGVFFPTP
ECSGGSGAPRASAPAEKRRESASASRDRDPGAADWKEETGNTAQALRERPPTEVAPQVDG
EETCVSDGVHERNRQDEGGGSEEGRRKAAGGETEKQGDDRKDLLHFESRLTH
>A0A0A1FID6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Collimonas arenae|TrEMBL
MILCQISDLHIKAHGKKSYRVVDTAESLRCCVAQINQLKQRPDAVVITGDLVDFGLPEEY
AFLRLLLQPLTMPYYLLPGNHDDRDALRAAFPEHSYLQQGTDRIEYVIDEHPLRIVALDT
VIPQSSGGALAAASLAWLDKVLTAQPDTPTVIVMHHPPFKTGIGHMDNIGLAQPHALAAV
VQAHPQVERILCGHLHRAIQVRFGGTIASTCPGVAHQVALDLSPQAASRFVMEPPAFQLH
LWDADAGLISHTAYIGEFDGPYPFYDGDKLID
>A0A3S4DYI0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella aerogenes|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QIARQILGSLNYPLYLIPGNHDDKALFLEYLQPLCPQLGSDANNMRYAVDDFATRLLFID
SSRAGTSKGWLTDETISWLEAQLFDGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTLPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A095AWC8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sphingopyxis sp. LC81|TrEMBL
MLIAQITDIHIGFDPDNPAEYNRKRLDEVLDVLIEGPNRPDLLLATGDLSDRGDDDSYRR
LATAFSRCPFPVWPSVGNHDLRDNFHARFPGLDDGNGFVQYTIELPELRLVTIDTLEEGR
HGGAFCDRRAAWLDAELAKDSAKPTYIVMHHPPIESGIEWMNTDPDEPWVAVFTDVVRRH
PQVRGLICGHLHRSVTVAWEGRTIAICSSTAPQVSLDLRPIDENKPDDRPMIVAEDPAYA
LHRWNGRELVSFYDHAGAHTMLAKYDERLQPLVRELKAERPRQ
>A0A212IU04|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Desulfovibrio sp|TrEMBL
MFVAHISDPHVGAGRSLAFNVSDGALLLEKTVSHIAALPQLPDCLVLSGDISVNGQPGGY
VIAAEALSALPMPVYVLPGNHDKRENLVAGLGQYCPADAAVTPYLCYTVEDFPLRLVFFD
GTRPGSHSGHFDAPVAAWLEKTLAAQPGRPTLVFTHHPPFITALGVMDEPYENGESLGRI
LEKFPNVRLCCGHLHRYMFTMWHGVAALTAPPVCMHIVPDFCATGGDDFTDEAPAFLLHH
FVDGRVNTHYCRVPGEFAERGPFSFSHPPKLG
>A0A128FK78|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Grimontia marina|TrEMBL
MTRIIQLTDTHVVCPPNKVSGVLDTLALFEDAITKIEQDLERLGHVDAIIVTGDITDHGD
VESYDAFKAVVRRLGIPYFVIPGNHDLRSSMHHCFENLTPATSEEINWVKHFPDLDIIGL
DTVIPGQGGGRLSPNALAFLEHALTSQPDKPALIAMHHPPFASGIQFMDAIGLEGADEMT
EILEKSPRDVRIICGHLHNSIVSTIGGATVLSSPATASSFLTDHRSDAPVGFTQDPGGYM
LHEWNKGFRSTYLPLTPSSQLYPFER
>Q7PWH3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Anopheles gambiae|TrEMBL
QTQNNRRLADEDDELSEVQPDAVPPEVREWLASTFTRQLATTRKKSDEKPKFRSVAHAIR
AGIFVDRIYRRVSSTALMQFPPEVVRVLKTLDDWSFDVFALAEAGNCQPVKYLGYDLLNR
YGMIHKFKVPPATLETFLTRIEEGYCRFRNPYHNNLHAADVAQTVHHVLCQTGLMHWLTD
LEIFATLLAALIHDYEHTGTTNNFHVMSGSDTAMLYNDRAVLENHHISAAFRVLKEDDCN
VLQNLSRDEFRELRTLIIDMVLATDMSFHFQQLKNMRNLLTLAEPQVDKSKALSLVLHCC
DISHPAKRWDIHHKWTMLLLEEFFRQGDLERELGLPFSPLCDRNNTLVAESQIGFIEFIV
EPSMTVCADMLEIVLAPIAPI
>A0A238DLM8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thiomonas sp. X19|TrEMBL
MILCQISDLHIKRKGALAYGRVDTAGFLARCLDRIRALRPLPDAVVITGDLVDRGDAEEY
AHLRELLAALPMPHYLLVGNHDGRQALRAAFPDHTYLDSGDGFVHYTADLGPCRLIALDT
QDPPHSGGRLCEARLRWLGQELEHADGQPVILAMHHPPFVTGIGHMDAIGLPAADCARLG
AVVARHPNIERILCGHLHRPIQHRFAGTLASTCPSPAHQVAFDIRPDAPSAYRMEPPAFE
IHAWLPGAGLVSHLVAVDESPGPYPFFHQDGQLID
>A0A086LF24|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii FOU|TrEMBL
MAASKTKPKSGGMFAGSASLAGSRRTLQGGLNSAGVPSGFFGQKSMRLGSIRLGSTHNST
TALKTTHQEKTYAMYHTYDAAVTENGGKLEVSHLVMFVLLTITILATTSCSFYFISRKNL
VMDTVDQLDQEAAAVRNVTMTLDIAEAAAQWSYSLDTRPFAEAAVITPELIFAVQGRFVG
AANMILSALETLRNADLAASTSSKCVSPDQTSQGGKQPCPLKKLLSQLRQIDTGLHDAMM
AVVLKDRLKLTEVLNEVIVNRLPGAWEEVTGPMSFLFFTAREHDKVKAAVQTYLSKLDKL
TADLASELDWESPMWCASATAATLSLTLIAFLIAVAVFSRRLQEAFGACQKAFFESVEEL
RAKIDEMTDFMHATFEFRITASLHVLNGVAALLGASSTLTPYHQKVLKLMEKCVVDTEAA
TVNAVSCLCSEIEIPQLGTEETNIRAIVEDCLEIFASKTEARGLPVTCTFGAGCPSVALV
DSHKLRTILTKVLSFVVDHTFEKGRGVDVFVNANASASRQGDSLEEFRGFDIHFEVKGHG
VCMENREAQELGHPKSLLRRAGHGLRMLCTAKLLQTMGGTMQILSSPSRGMLVSFQIRTR
ARFRLLDFQKDFRASFSQQRRQRIISLGLAPETSRALQFLCKDVGIQFTACYCLRHLRES
LATETKTFSLAFVLGDFVTISANAADPASRPLTSAEIFREAQEAAALRPPPGCCLPLVKV
FVSSRGDRSSQDGDEKVESRQHPLPDDVTKLSVPVRTDALIQILARALDSVEGCKSADAS
S
>A0A0M6Y2Y6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseibium aggregatum|TrEMBL
MTKIIQISDTHIVPEGALAYGQVDTAAALAETVATINRLLPQIGPVDLVIVTGDLTEHGT
PEEYDRFKMLMADLDLPYRVLPGNHDRREPMRESFADAQWMPRTAPLDWQIDFEDFAVVG
LDSLTESAAHGTLEPATLSFLTDALSGLGDKPAIVGFHHPPFAVGIRAMDAQNLHDADSM
GTALSLHSGQVRLVCGHLHRSIAGLFSGSLCQVCPGTSHAVTLDQRANAGNSLTKEPGGM
LLHEWRDDGFLTHLIPVGAFPGPYPFLGVS
>A0A0L0LZH3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Paraburkholderia kirkii|TrEMBL
MLLAQITDLHVTLPGTLAYGRVDTAAYLARAIDALNALDPRPDAVLVTGDLVDAGGIDEY
RHLRALLDRLAMLWRVLVGNHDDRGNLHAVFGDRPKLAGDGAFVQYAYDVGEVRVIALDT
LDPGSPAGRLCAARLAWLEAQLEASRERPVVIGMHHPPFACGIGFMDDIRLATDDSRALE
ALLRRHPNVERVVCGHVHRAISARFGGTIAWCAPSTAHQVALQLTPGAADAFVMEPPAFG
LHLWRADLGLVTHCVSVEQGGGPQPF
>A0A6F9AZ51|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Coregonus sp. 'balchen'|TrEMBL
GEECWISLSERLAEQAAEQSRVLQLYSSSSPSPVTVASGAPVWALVTAAAPSKEEDTVHS
WENALLLRCLVKQLDKGEVNVVDLRKNIEYAASVLEAVYIDETRRLLDTEDELSDIQTDS
VPMEVRDWLASTFTRKMGVVRRRPEEKPRFKSIVHAVQAGIFVERMYRRTSNMAGLTYPP
AAIAALKDVDNWCFDVFVLHEASSEHALKFLVYELLTRYDLINRFRIPVSSLVSFVEALE
VGYSKHRNPYHNLIHAADVTQTAHYLMLHTGIMVAILYNDRSVLENHHVSAAYRLMQEDE
MNILVNLSKDDWRELRTLVIEMVMSTDMSCHFQQIKTMRNALQQPEGVDKAKALSLMLHA
ADISHPAKAWKLHYRWTQALMEEFFRQGDKEVELGLPFSPLCDRKATMIAQSQIGFIDFI
VEPTFSVLVDTTEKIITPLIEDTLKSHDTGVRRSSLTGSGSVTVVESVQKHSGRGSSQGV
DQGLATDYSLTGINLKRVRHTLAEVIQHNKDRWKELSVHELASKERAELNTDPEEEESQM
NTGVTLTHTSPERHSQELQSEPFNELMNNTNSNNSSQEDSELDNHPHSPLSPCEDKETRS
PDSISPECLPWNGEGPGAVLESGEESLQSP
>A0A3S4NGY2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Achromobacter spanius|TrEMBL
MLIAQITDLHMRTPGDKAYGVIDPAAFLAPAVRALNALTPRPDCVLITGDLTDLGRPHEY
QVLRDHLSALEIPYFLLPGNHDDRAELRAAFPDHHYLQGGGPFIQYAIETYPLRMLALDT
VVPMKSHGELCQDRLDWLAARLAEQPDRPTLVLMHHPPFLTGIEHMDAIGLLAGAPELER
IVSRFPKVERVLCGHLHRTIFQRFGGTIASTCPGTAHQLALELGPRPTLQYIMEPPGYQL
HWWQGENLVTHHAVIGEYPGPYPFA
>U6FJI0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactobacillus helveticus CIRM-BIA 101|TrEMBL
MNKGYVVDDAVELRRLCSRYNVKLAFTRHINAQNIMDPQETTPTTEVVTSSFCSNDQGYG
VVRVHSRHITYVRRNFDMTRYLTDQEKENYTLEHFHKYLKDLQLGSISADMMQSELNKIH
SSQAHQVLIKHHPEYRLYLEILYDTTSHSNLQVKIRY
>A0A422NGZ4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Trypanosoma rangeli|TrEMBL
MKTHLSHVPVNRPEVTPKERLMARFIAQLRRRLAESTTLDEFRAWVGEHAEALEASVLEA
RPRQRVDTFQDIFATPTTPGSISENGDEGIESATYWGYGEQGNTFASYPSLTELVCVDSP
SSNAKTYKNSSRMTVASEFTPVASLKREKSLLMHSAGSINYCEDTKTDKDVTSVLQLSSL
WAPSVFQRGASKLPGRGKQGRDCETNPLESGDSCGSINQSFSLLAESIYSSAGMTHRPGA
PPLPKDMSILDLSNQGELGEGMPAFSLDGRFPNQGPIFSRSNSRHSPVLRPVAQVREALR
TLGVPFLENVESSNVDVLQYEEIYGVNAYVYTCLNILLRYNFSVQLGFHLGRLLCYYNTA
AKYIFWRNPFHSICHATDIVLAAHQFLQQPYVAENFSDEELFSFLFASTVMKLGHVGMSN
AFLISIHHPYAAFHGFLSPQQSISIALGFALLDAPECHFPTFAAAQEGTDNYMPSLWTPA
KEIEFQEMTSRLIIPTDERDHQMLLTQLQQVLQEGAGNVVRESHLMIILQNVLHAADFCY
VFRSPPVYRATAARAVAEIYQQEQTRLWFQGNGVIRWPWHEVNFGTGEEGLTPQTNNNTL
EGSPISIEDTLIFKNDSHQMKAPLSSFDVPGGITFSDASIKSSAGSFCGVSGFSSLYHAK
VLQLTVLEAVFLPFIFTLSPFVPDYWLTNAQSNLVWLDDFHPDVFEADVMRVLRNPEFGG
PRLRSAGPCGFERRVVRRILDPLFRHRKEELKKWTGS
>A0A4V6JIB2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serratia rubidaea|TrEMBL
MRCWTRCAPNSGSFDLVVATGDLAQDHTPEAYRHFADGISQLPAPCVWLPGNHDFQPAMV
DALAAAGITPSKHVLLGEHWQVILLDSQVFGVPHGELSEYQLEWMERCLQAYPDRYTLLL
LHHHPLPSGCTWLDQHSLRNPHMLGAVLLRYPKVNTLLCGHIHQELDLGWQGRRLLASPS
TCVQFKPHCTNFTIDDVSPGWRYLDLLPDGRVETQVCRLDNDDFRPDMDSDGY
>A0A840YMC1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sphingomonas xinjiangensis|TrEMBL
MRAFALAALLATAAAPAPSGFDMVVLGARGGIEDGNLSSYLIRPQGDPRGVTCDAGTLVQ
GLRVAEAKGAFKDVRVSAGEELSRVGYVLKHDIKGYLISHPHLDHLSGLIIASPDDAAKP
IYALPSVNAEIARSYFRPGPWSNFTDRGAEPRLGKYHVVDLKPGTPTPLAGTTMTVTPFP
LAHGGMESTAFLLEHDRDAMLCFGDTGPDAVEHADKLQRVWSAVAGRVRAKQLKAIVIEV
SFANDRPDDKLFGHLTPRHLLGELHKLEALAGKGSLKDLPIIIGHIKYALSGTQPQAQIL
SELGAGNDMGVRFHIAEQGQRWRF
>A0A2T6J004|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii TgCATBr9|TrEMBL
MHRLLDWDFHVLALPPASAVLVTRDLLTQFALKANMDIPGEILMAFSVAIYKNYRPNPYH
NFYHALNVTQVLCLLLALPDVAAQFSPIDYLVLSVAALGHDLGHPGANNLFMTRFDCWPS
RIYQNVSVLENYHAASLFQILRHPAFNVFCSVSPTNFAPIRKRIISAILWTDMAKHFDVV
AKLQAKIQGEMVLAEGIIVTLTKPYLEGLLLHAADISNPMMDFELCRDWAFRACDEFYQQ
NKMEEMGGFPPSMPSFEHFDEYNVAKCQVGFIDAICKPLFNSLALMFPAQLGDRATQLQK
NRCVPLIIFPT
>Q7UEL5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)|TrEMBL
MKILHISDVHFGPPYLPNVGEALLRTAPSIDPDVVVVSGDLTQRAKPQQFQQAAEFIKQL
PDVPRIVIPGNHDVPLYRIMERLTDPHRYYRQYISNELNTVLQTPDALFVGLDSTAPRSA
ISNGRIHPSQLDFCRDAFGSVPDGLAKIVVAHHHFAPAPDYLHDQTMPKAKRAINLFVKL
GVELILGGHLHRAFIGNTLDFYPGAGRAHGIVIVQCGTTTSRRGRGREKEKNSFNEIDVT
EQTIIVTHHIFDDQTGQFAPLSRHEFARGGRRLENASPRSSHNPRATKSIESNPLPQTLR
STRV
>A0A6J4JX23|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Corynebacteriales bacterium|TrEMBL
MSDLPAPIRVPYRLAGTALSTVLAAGSALRHARVFHPVGVAYAVTVDVEPDGTGPWGAPL
LDRPATLTGLVRLSRGTGLPDGLPDVLGLALRLTDAHGPGRHQDLLVNTAGRGPLVRQVF
LPARGFGTGRYSSVLPYRVGAARVLFGARPVGPGDLRTFAELDRAAAAGALRFRLEVARP
GGRWRPVGTITVGERLPAEVAEELRFNVNEHTGGGIAPVGALQELRRQSYRLSQRHRP
>A0A2T6IFU4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii TgCATBr9|TrEMBL
MHISCVKGRIVARQIDNVFTVIFAIEVLGKFVSYGLEYLQDPIESFDTIVVLTSFTLLVL
GFYVSGIGLLRILRLLSALALLHKYPDSKEKRPELSAGNSSKLEKASSIVEGLLTNVHIP
KYFKTELEWVWDSILANKVYDSHVVENEEEEEDQATETIIAGSDASRKTQAAVRASRAQS
RASKLPHGSSSMVVGTTNGRISGQILETLREPDPRMMDAALYKSETRNLDPLTATVGGMK
NSPSMFAKGSKSSNMMGSSASKSFRTERNKKAIDIISVLYQASQITGAEQEQVNEAMRPF
DEWQWDALHAGDVCDMNLLPVVFVRAIATFPTIMTKFNFDLDRLFDFLKVVQTSFQKNVK
FHCAAHTADMIQAMHYFLTIGKLGALLSEYDVFLCHFCALVCHFGHPGVTNTFLVKSRHP
RAIRYDDESVNENYVASAISCLVAREEYNFFGDKLPLWQVFRLHMIDILLNFDISKSAHQ
VAMFRTKVSIKFTASTPADKQLLLTILLRAADYSFTCRQLALYSKWKDRMIDEFFAMGDT
EKQLALTVSPFCDRELTNVDKCHVAFAEVAVKPLMTVLVLGLAPHLQKDVLDTLEANQKN
LMQKLDKSD
>A0A085FX30|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bosea sp. LC85|TrEMBL
MIIAQLSDFHVRPHGQPAYGIVDTNAATRRAVDAVLALEPRPDCVLVTGDLCDCGLPEEY
EIVRAELARLPMPVYAVPGNHDRREVFAAMLGEGSSYLPKSGFLHYTIEDYPVRLIGLDT
VIPGEDGGEICGEREAWLAERLGEGRGRPTLIFMHHPPFAVGVDGMDIMPCRVSPDFVAL
IARHPEIERVLCGHYHRPIQLRFAGTIGFVAPGTAHQVALDLRPGTQNWFVMEPPAIAIH
VWKPETGLVSHLQPIGDFGPRRPFVLDPAYPGKQQAVAAHV
>A0A5C6B343|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Symmachiella macrocystis|TrEMBL
MTTHILQLSDFHLLKNHADELRGVPTADCLTDLLTLVRANYSAADLFVLSGDIAAYGDVE
AYHQTRELLADLLPRCVMIPGNHDETDLMRQAFPETIAGSPGPVTFSCDVAGWRMIGLDS
HVAGAVHGELCGDQLQWLADEFSQHRDQATLLFMHHPPISVESTWLDRIMLRNANDLTKV
LHAAPQVRGIFCGHVHQEFSGSFGAIPVHTTPATAIQFAPHTEELQFDNVPPGFRVIELD
GDKFHTHIVRLPELKYPAT
>A0A6N2YPT0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Enterococcus casseliflavus|TrEMBL
MNVLHISDIHFRESYLSCEEGYQGMLAAMQNPLIPLEECIQDAKARAAIDLVVISGDLTE
DGAPADYASLKQYLEKAFGSVPIVVTLGNHDIKRHFRQGWQGKSVETASDTPFNQVYETE
TLAIVTFDNSCYGYADGIVDERQFEWLQATLAQLKEKKIVFVTHHHLLPDQASTPAWAGA
NRLVALLQQYQISCILSGHTHHAFTGTIAGIPYYTVASMSFVGEDEGDGMVRFEERYGYN
LYRFEEGALVHQSSENYRPNRVLMRVNMQG
>A0A3S4C951|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Devosia equisanguinis|TrEMBL
MAETTFIHLTDLHVGNPAVPDDHLFSDTSATLGRVLELIGSIDNKPSFIIASGDLTNRGD
ADSYRHLKSLMAATDLPVVYALGNHDTRPGFYQGMLERETDLDAPYDHEQVIAGVHIITL
DTTTPGQVGGAIEPEQFAWLEETLDSHPDLPKLIVAHHAPVLGDTVPWDHWRTIEFNQSQ
QLAALLKGRNVLAILSGHIHHDRFSVWHGIPVIVGMGQHAATDILTTDVLRMVEGASFGI
GTIRRSGLTMALVPLPQTRSELNRYDLSKLRQKQEAALAEAAAS
>A0A086KWL7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii GAB2-2007-GAL-DOM2|TrEMBL
ILFVAPSSVASRRCSRPSLETELRSSERTETNGNPSSMGMNVGRH
>A0A239SJF5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pandoraea sputorum|TrEMBL
MSDRDPKDDGKDVVDAPAMSRRRAMACLAWAGAGILWTLDGGVPRGLPLATMLGGTTASA
AGNPLSGTLSFVQISDSHIGFNKAPNPDPAATLQSAIERIRSASQRPAFMLHTGDVSHLS
RAEEFDTAQQIVNGAGLETHYVPGEHDVIGDDGRAFFSRFSPRSGGNGWYSFDQQGVHFI
ALVNVLNLKAGGMGYLGDTQLDWLAADLKGRSRSTPLVVFTHMPLWSVYPAWGWGTDDGD
RALALLRPFGSVTVLNGHIHQVLQKVEGNVRLQTAMSTAFPQPAPGDGPGPGPLKVDASQ
LRQTLGIRRVDFTSLDGAPLLGDTTLAS
>A0A173ZCM5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Anaerostipes hadrus|TrEMBL
MKVIQISDFHLRGDGKLSFQKADTMKALHQTIDYFCSMKDYELPEFFVVTGDLSEGGTRE
GYEFMREGLRKLPRPVYIVPGNHDKRDFFLEMFTEETPVKEDIKPYICYTIDEYPVRVIV
IDTSKPSCHSGGLSDRVAEWLEERITEYPEKPTLVFTHHPPFVTGLPAMDEGFDQADRLA
QIINKHENVTLCCGHMHTAIFTSWHKIPCVTCPPIAMQMEVDFRGKNDINLTEEEKKEEF
KGGGDRFFLGNPGYLIHDLQGDRINTHYQTIPTGADYSGPWPFKYYEGEED
>A0A1Q8JHD0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudonocardia sp. Ae356_Ps1|TrEMBL
MITVVQLSDLHLGVPGNRERAVRAVAGARALGADLLLVTGDVADHGDPAEYAEAAELLGG
AAVLPVPGNHDDRDAMGTVLGPVGDRVHRAGGVNVVLLDSLVPGAPEGALSAGAVDLLAD
TARDPAPLLVALHHPPVPVGHPFMDGIRLRDAEPFAAVLAARTEPALVVCGHVHRPVATT
VGGHPLVVAPSVGPAIRFPGEPGEEFLLPDSVPGGALHVLGDGPPRTRFLAWP
>A0A1W7MA94|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Novosphingobium sp. MD-1|TrEMBL
MLIAQITDIHLGFEPDTPDEFNRLRLDRTVQALLEMDPRPDLLLATGDLVDRGDRESYER
LREALSGLPFPVHFALGNHDERATFREVFPQAPFAGDYLQYVIDSPALRLIVLDTLEEGR
HGGAFCEERAAWLAARLDEDTVKPTLIVQHHPPIEAGIPWMNTDAAEPWVERLATCLRGR
DNVTGLVCGHIHRASATRWEHVIVATCPSTAPQVALDLRPIDPDVPDQRNLIVADPPAYA
LHWWNGRELVTHWDTAEDRLVLARYDADLQQMIQHMLAERPDAGLAGAGMAAAE
>A0A5C5YJJ4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodopirellula solitaria|TrEMBL
MPINPQRLDSQRLGRRALLENSTLLLTAASMAPATVFADDVPSPFKIGLVTDLHYADKPV
AGNRYYRETLAKLEQAALQFEQADPAFIVELGDLIDAADSVQTEQRYLKTINREFATICS
ERHYVLGNHCVDTLRKEEFLGGVGQEKSYYSFNQGGFHFIVLDACFRSDGQPYGRKNSVW
TDANIPPAELDWLQADLKSNQSPVIVFAHQRLDVSNSHGVKNNADVRRVLEESGNVRVVF
QGHSHQNDLKDIGGIHYCTLVAMVEGSGTDNNGYSTLNLYRDGTIAVDGFRKQADYRW
>A0A8D1E9M6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sus scrofa|TrEMBL
MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD
LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR
SEEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS
GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV
HYLLYKTGVANWTLEKEILNIVNSASLDSHEKKKATNNCHITFRSDPAILYNDRSVLENH
HLSAAYRLLQEDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPE
AIEKPKALSLMLHTADISHPAKAWELHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKS
TMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNNISSSDAKR
STVKSSGSEGSAPINNSVIPVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKAR
LAAEEKQKEMEAKSQAEDGAAGKAEKKASGEAKTHPVNGTRTNKSDNPRGKNPKAEKSAG
EKQQNGDLKEGKNKTDKKDQSSVGNDSKKADECKEWTKDNPWTSASSKSCLTL
>A0A1S8L7P9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium felsineum DSM 794|TrEMBL
MNKIKFLFLFIIALIITTILVSTPESTSKVSANHILQYSFSVISDTHIGVDESKNSSKIA
KNKLAIALKCIEKNFPKDKCIVINGDVVDNYYESSYNELTNIILNVNYSKKLPYIYFNLG
NHEFKYNGEGPSISECYNENLNRFINKTQNIQSKLTANKDISHTFRSTNKPYDLQYVSNT
PFFFLGSDSVAKGKTNDCAYLKFNDQLKSLNDSIGTGLSFIFCHQPPFNTVKGSNASNCI
SNTNELLEVFKKHPNAIMFTAHTHRTFDNSPLTFGNNYSKLGSCPVITSPSVFRSLEGIH
VNVYEDMISVEGVKYHSDYHCTTKPDWCITFR
>A0A086J701|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii p89|TrEMBL
MFDRRKHADFPKGQEGFLRFIIIPLYEEIAAVDTTDVVQTCCLQNAVANSERWRQLQSSP
EEFEAIDAKHQAIICVLKDRLEWRVQKNIAPTQRLLRASCAENQVRGSGVFFPTPECSGG
SGAPRASAPAEKRRESASASRDRDPGAADWKEETGNTAQALRERPPTEVAPQVDGEETCV
SDGVHERNRQDEGGGSEEGRRKAAGGETEKQGDDRKDLLHFESRLTH
>K8CIN4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cronobacter sakazakii 701|TrEMBL
MLAGIPAYICGSVCPANPLWLGGAHVPAVFDPPALMVHRLEKGTLASHFMAVSPVNDR
>A0A091GDK7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cuculus canorus|TrEMBL
RLRYMVKQLETGEVNVEELKRNLEYAASLLEAVYIDETRQMLDTEDELREIGSDAAVPSE
VRDWLAATFTQQARAKGRRAEEKPKFRSIVHAVQAGIFVERMFRRTNTAVGPSYSTSVLN
CLKSLDLWCFDVFALNRVTDDHSLRTIVYELFTRHNLNSRFKIPPVFLTTLLDALEAGYG
KYRNPYHNQVHAADVTQTVHCFLLRTGVLHYLTEIEVLAVIFAAAIHDYEHTGTTNSFHI
QTKSDCAILYNDRSVLENHHISAVFRMMQDDEMNIFVNLTKDEFAELRALVIEMVLATDM
SCHFQQVKSMKTSLQQLERIDKSKVLSLLLHAADISHPTKQWSVHSRWTKALMEEFFRQG
DKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKMVMPLAEDGTKAK
>A0A2S3U278|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactiplantibacillus plantarum subsp. plantarum|TrEMBL
MRPLQVIQISDLHLTPRGQVPAHGQQYDPWGKLANIIDDIRRLPTMPDLIVFTGDLIHDG
SADDYQRLHAIIHTMEAEFDCHVRVILGNHDRRAAFYEGYLPADPGPYYASRMRIGNNDF
YFLDSKVSGYEAGWLAPQQLQWLGKHLRQAPTKRAFLFLHHPLDGPTMTNMHYAILQNTP
ALLSVLRGHNLGGVFSGHVHFVSSYLIGDNILNVVAGSAAYAIDCHDPHHHYVHEGSSYQ
IITIDRGQVGVTTRQLLHGKAVIDELTIPDTKFVGRAPQGYE
>A0A1X7BLZ7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseovarius aestuarii|TrEMBL
MTKIIQISDPHIVPHGQLAYGRVDTATPLSDCVETINRMLPQIGPVDMVIVTGDLTDFGT
AEEYQRFRDIMEPLQIPFRAVPGNHDDLDAMRSSFSDQDWMPKTGPINWTQDFSDLVLIG
LDSSVSGKPHGHLSAATLGYLQQALDSACEKPVIVGVHHPPFLTGKEKMDIQNLRDSAAL
SEILSAYRGEAKLICGHVHRNIVTLFGNVICQIAPGTSHAVTMDQRIAAPNCLTREPGGF
LLHEIRGGLVSHHIPVGQFDGPWLFYPDNSHGG
>A0A3S9LTC8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli|TrEMBL
MSDPVRITNPGAESLGYDSDGHEIMAVDIYVNPPRVDVFHGTPPAWSSFGNKTIWGGNEW
VDDSPTRSDIEKRDKEITAYKNTLSAQQKENENKRTEAGKRLSAAIAAREKDENTLKTLR
AGNADAADITRQEFRLLQAELREYGFRTEIAGYDALRLHTESRMLFADADSLRISPREAR
SLIEQAEKRQKDAQNADKKAADMLAEYERRKGILDTRLSELEKNGGAALAVLDAQQARLL
GQQTRNDRAISEARNKLSSVTESLKTARNALTRAEQQLTQQKNTPDGKTIVSPEKFPGRS
STNHSIVVSGDPRFAGTIKITTSAVIDNRANLNYLLTHSGLDYKRNILNDRNPVVTEDVE
GDKKIYNAEVAEWDKLRQRLLDARNKITSAESAINSARNNVSARTNEQKHANDALNALLK
EKENIRSQLADINQKIAEEKRKRDEINMVKDAIKLTSDFYRTIYDEFGKQASELAKELAS
VSQGKQIKSVDDALNAFDKFRNNLNKKYNIQDRMAISKALEAINQVHMAENFKLFSKAFG
FTGKVIDRYDVAVELQKAVKTDNWRPFFVKLESLAAGRAASAVTAWAFSVMLGTPVGILG
FAIIMAAVSALVVNDKFIEQVNKLIGI
>A0A3G2S2Y8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Malassezia restricta CBS 7877|TrEMBL
MEGTASLSVPEALASNCDATSNNDLSTNNPDEPAATAAFSFVCLGVGGGPFDDDCSCYVM
KPADRAWHEGTVLVEGGSFLGSLKKCLQPPDSVFYDAEFPPDVDADGRTEIFNSWINNVF
ISHGHLDHIYGLVLASANNRVQRPVYGLEDTLETILTVFNGRIWPRLASYDESDPMAFYH
LRTLKINAPLRIAPEVDVTAFPISHGPARLSEGTTCFNDEILHAEPIEHPPCEMDGTFCR
TVSTAFLFTNHRRDMDVLFMGDVEPDLVCHSSCNSTLWENVAPRAAQNKLKAVFLECSFS
SEQPTHLLFGHLTPEYLYKELECLARHVRLCQHQDENLLEGSLRGLKCIVIHLKGLVLSA
DPSYTTCTPVPKSSSSEHLPLPVPLRERIQNELDALESKKRLGVEFIIAQRGQRIEC
>A0A1E7XBP0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lentilactobacillus sunkii|TrEMBL
MRIGFVSDLHMDFNRQYDFVTVLQQLINDERLDKLVIMGDSANGLQRNLLFYERLEDNIS
IPFYTLVGNHDLYVDHPREKTVHEIQQASRNAYHDLDNLPMSLTKHPIETDHWVITGING
WYDYTFANGFSEAKGPRYADNFVAKHVWPDQMYINGNQISYRRDRLWVTQQIFDWQHQIN
QMNVTGKKLLVASHMLPTKKLARQMPIPFYDRFMYQLGSDRYRQIFEHNHVSLSLSGHSH
MPNSLAENGIRYRNLSLGYDFQWQNPGDALNELKHVMYVLED
>A0A7W9XG51|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mucilaginibacter sp. SP1R1|TrEMBL
MCHKKASLIIIYILLPFLALAQTKNNQTFRLVPLGVFGGIDESNLSAYMLAASGSNNYIC
LDAGTLHYGIQKAVANKAFTIPADQVLKQYIKGYFISHAHLDHIAGLIINSPEDSSKNIY
GLQSTIETIKTHYFTWQSWANFADQGEAPALKKYHYQVLTPGTETAVDNTELKVQAFPLS
HSNLTSTAFLVQSNGSYILYLGDTGPDAIEKSNNMQNLWQAVAPLIKAKKLKAILIEVSF
PNEQPDKTLFGHLTPHWLMTEMEKLAALTSLEELRGLNIVITHLKPPAGNIIKIKTQLKA
TNKLQLNLIYPEQGKVINF
>A0A087RPN3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Marine Group I thaumarchaeote SCGC AAA799-D11|TrEMBL
MIIVQISDLHVGSQFLEEKFNVLVNEVNELNPDVIVITGDLTNEGLMKEYEKCKSLLEKF
NTKKIIAISGNHDYRNTGYLLFKKFFPFQTVNELSDDVVLVTVGTARPDRNEGEVGYRQN
LWLERTMKKFKDKIKIVAMHHHLIAIPDTGSDQLTVVDAGDVLRTVLDSKVDVVLCGHKH
RPWAWNFGTLTVVNAGTATSERVRGLFENTYNILTIENKKVQVDLKIVGGKRVPIDEIVK
NYSQFHDELDNV
>A0A482Z020|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|bacterium endosymbiont of Bathymodiolus sp. 5 South|TrEMBL
MKHFIQISDCHIDDNAQTMGVNSHENLIKVVDEIVTLQSDALLISGDLTHNGTPYSYKKL
KEILSPIETDIFVIAGNHDDSDNLASEFSACLFDRIALDAWDIINIDSVQIGKTSGFVTT
NALTALDQQLQHSNAKYNLIVLHHPIVAMNSEWDDALSLENPQDLFAVLDKYPKVQAVLF
GHAHESVEFDKNGLKIIACPSTATQFNDEQRIGFNYYTLFDDGRLDYETQWINS
>A0A2R7WN82|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oncopeltus fasciatus|TrEMBL
MVGNRRLADDDDELSEVQPDAVPPEVREWLTATFTRQVGPTKRRSEEKPKFKSVAHAIRA
GIFVDRIYRRVTSSSIMQFPPNVVRVLKTLDEWSFDVFALNEASNRTPIKYLTYDLLNRY
GIFHKFKMVPATLDNFLSKIEEGYCKFRNPYHNNLHATDVTQTVHYMLCQTGLMNWLTDL
EIFATLLAALIHDYEHTGTTNNFHVMSGTDTALLYNDRAVLENHHISAAFRLLKEEDCNI
LVNVSVDEYREFRSLVIDMVLATDMSFHFQQLKNMKSIISLGEANVDKSKVLSLVLHCCD
IAHPAKRWDLHHRWTTRLLEEFFRQGDMERELGLPFSPLCDRNNTMVAESQIGSL
>A0A0F7XRK7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. CCOS 191|TrEMBL
MPQPLSPPSPVHVVQLTDAHLFADPAGTLLGLNTRASLGHVVGQVRREQPRIDLLLCTGD
LSQDASVESYAAFRELTSTLGAPARWLPGNHDEARVMAEVAPELVQAVTDIGAWRIVMLD
SAVVGATFGLLADDQLVVLDQALNGAGERHCLVCCHHQPVDIGCAWIAPIGLHNADELLR
RLRSYPQVKALLWGHIHQEWDEVRDGIRFLATPSTCIQFAPRSEDFKVSEEQPGYRWLRL
HADGRLETGVERARDFVVKLDFDSPGY
>A0A5N5SP31|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Armadillidium nasatum|TrEMBL
RLGEEEDELSEVEPDAVPPEVREWLASTFTKQLQGGRRRNEEKQRVDEWNFNLWLLHDVS
ANTPLRCLGYEFLNRYGLLHKFKVPPASLENFLSQVEAGYCKYKNPYHNNIHAADVLQTI
HYMLSQTGLMNWLTDIEVFATLFAALVHDLEHTGTTNNFHVMSGTDTALLYNDRAVLENH
HISAAFRLLKGDETNILVNLSREEYREFRSLVIDMVLATDMSSHFQQIKAMKTLLSLPEP
TLDKSKALSLTLHCCDISHPSKEWRTHEKWTMNLLEEFFRQGDKEKELGLPYSP
>A0A379A8V1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nocardia brasiliensis|TrEMBL
MILVAQVSDTHFDLGARNAARVERVMAFLTGLRHRPDAILVTGDVTDSGKPEQYEQARRA
FEVDIPVYAIPGNHDDRATFRSVLLGTAASTAPINQTHRIGDLTVALLDSSIPGEPSGLL
TEDTYAWLRDLLAAAPADKPVLVALHHPPAHLFSPIVDEIALAEPEKLAELVAGDERIIA
VLTGHAHSAATTTFAGRPLLVAPSTASVLGGEWELDPPDHVMDYAPDPAIALHIIDEKHG
LTTHFRSVPMGGRVGVPPS
>A0A0P1IPW8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cognatishimia activa|TrEMBL
MKIIHISDIHFTIPGERMGGLNPHKRLAKALADVNENHSDAARIVITGDLTHWAEREAYD
ALHEVLAKQTVPVRLMIGNHDDRSIFLSVFSDQATDELGYVNHSEVVGDSTFIYLDSTQP
LTHAGHFGADRCAWLEAELQQAEHARIFLHHNPMEIKLPAEDQIALVAEDRLLFKDLLNT
YRDRIDYIHFGHVHAPIHGTYCGIPFASVPSTCNQSYPDMKEAKLLAGGPMEPAYHVLLI
EGRETIIHQIPFNWDGPLFASGAEWEDWSKPVAAE
>A0A653ZUF5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. 9AZ|TrEMBL
MPGAPIQTTAVDRSVLLVQLSDSHLFADGAGKLLGMDTQDSLQRVIERVLQEQPQIDLVL
ASGDLSQDGSAESYQRFREMTAAIPAPARWFPGNHDEVPAMQAACVGSDLLEPVIDLGNW
RVTLLDSSIPGAVPGYLSEQQLALLERALSEAPDRHHLICLHHHPVSIGCKWMEPIGLRN
PDALFAVLERFSQVRAVLWGHIHQELDQQRGPIRLLASPSTCVQFAPGSEEFQVDKTAPG
YRWLRLFDDGRLETGVSRVTGIKFEIDYTIKGY
>A0A0C5V5T7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gynuella sunshinyii YC6258|TrEMBL
MLIAQLTDLHIKKGGKIAYQKVDTLQCLRAAVAHINALQPQPDWVVVTGDLGDFGRPDEY
AVLVPELKQLNMPVKVIPGNHDHRAALREAFAGFVTFDHDDYCHFVQSAGGYRLIGLDSS
VPGKPHGHVTAASLLWLADRLVESPDCPTLLFLHHPPLAVGLGHMDVQKLLNDDDLWQVV
RHHPQVKGLVVGHLHRPVYGTWHGLPVWVGPSHSHAVTLDLRADAPSSFSLEAPAIQLFK
LTPDSIVSHISYIRKAGEIQGPYPFFDEHNKLID
>A0A518CGT7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Polystyrenella longa|TrEMBL
MFRRDFLKTATLTSAGLMIPTSFSRLANADDEMKPAFRFVHLTDIHVQPEREGGAGMTKC
LEAVEALDPKPDFILTGGDLIYDAGKDYERGNQLFKLYKQIVADHTGIPVHPCVGNHDVY
GWSRREELDTMNPLFGKGLIRDHLELEKTYYAFDHNGWRFYVLDSIQPTVEKRYKYTAGL
DEEQMAWLQSDLAAKPKETPAVVVTHIPVLTVTSMRKQPELLGEDFYISGGPGMFSNSLE
MGRLFHNHNVKLALSGHLHEIDRIERGNVTYICDGAVCGGWWYGPNIDSGFEVQEGFGVV
DIHTDGTFEHHYVDYGWEAKVQTKG
>A0A1A9WXN5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Glossina brevipalpis|TrEMBL
MATSRRKADDKPKFRTVAHAIRAGIFVDRMYRRVNTTTLLQFPEDVVKTLKNLDDWSFDI
FHLAEATNGQPIKYLAYDLFSRYGLIPKFKIPPATLETFLHRVEEGYCRYRNPYHNNLHA
ADVTQTTHHMLCQTGLMNWLTDLEIFATILAAIIHDFEHTGTTNNFHVMSGSETALLYND
RAVLENHHISAAFRLLKNEDCNILSRLSREEYRELRSLIIEMVLATDMCSHFQQLKNMRN
LLTLNEATVDKPKALSLVLHCCDISHPAKRWNLHHRWTMLLLEEFFRQGDLERELGLPFS
PLCDRNNTLVAESQIGFIDFIVDPSMTILSDMLEHILSTINVSPPEEPSTEPDPITAFSR
RHSSRKHKILKPWVVWLTENKKIWKEQAIKDAAARLTEKIEKVETVDIENAKDDENTEQ
>K7ZZN1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cronobacter condimenti 1330|TrEMBL
MCQGRDALGVLLGAHPARPLAIATGHVHRPAAGMLAGIPAYICGSICPANPLWLGEAYVP
EAGDLPALIVHRYAHDALASHFISVTAV
>A0A1I7SAH7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bursaphelenchus xylophilus|TrEMBL
MFVFLRKTTIFEPHEALALFVAAICHDLDHRGKNNAYMKTMSTPLAAIYSTSVMEHHHFN
QTVTILQHDGHNVLRSLQPADYKKVLGAIKQHILATDLALFFPNKARLNELVAKGEFTWQ
DPSHRILAQALLMTSCDLVATAKPWQVQTETVKVIFEEFYEQGDAERLNGRDPQPMMDRS
HANELPQMQVGFITGICVPCYQAISQVVPEADELRERSEYNLKKWKELAEEQEQKKLQEN
GGG
>A0A7H4PQH1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella michiganensis|TrEMBL
MPTSSPKLNALQERPDAVVVSGDIVNCGRPEEYEVARQILGSLNYPLYLIPGNHDDKALF
LEYLHPLCPQLGSDAQNMHYAVDDFATRLLFIDSSRAGTSKGWLTEETIKWLEAQLFDGG
DKPATVFMHHPPLPLGNAQMDPIACENGHRLLALVERFPSLTRIFCGHNHSLTMTQYRQA
IISTIPGTVHQVPYFHEDTRPYYDLSPASCLMHRQVDEQWVSYQHPLTHYAGPWMYDENI
SCPTEDC
>A0A5P9IRZ5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Halomonas sp. THAF5a|TrEMBL
MRLVQITDCHLHADPAARGRIGVPLGQLEAVIAAVNREKPDRVVVSGDISQDETAASYAL
ATRTLSKLEAPWAWLPGNHDSPELMVEHQSLPAELDLGDWRALLLDTRVPGREGGELGPQ
RLTALDARLAGDDRPTLLVMHHPPLSIGTAWLDAIGLADAEAFWRCLAPYGQVRAVCFGH
VHQAFEGAQALAGRRVAVYGCPAASDQFLPGAATFALDEAARPGYRVLDLAPGGIETRVG
RVAP
>A0A161Y3Z7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium magnum DSM 2767|TrEMBL
MKHRWLHLSDLHSYCSGIKTKVMRDALINEVEELNNEEKFDFIIITGDISDKDSGYDLAE
EFILDLIYKLDIAKERVFIVPGNHDLSRNIPDNREDIVKELWGSGILDEESESNNISLLI
DAQNNFFITYKNLLGRDYPKENIHFVEKVIEGVNIIHLNTSWMCYDSNVEDGRIHVGLNN
VYKCLETINNEDFNIVIGHHRLEDLNPQERNNLKSIFRAKGIDMYLGGHCHQAIIEHDRN
ADMELCFCKQARAEFDDYPAGFILGNIDVDNNQSYYMFYNWSTSFAKWMYDYSVEAAKHG
KYYLKGEKYNKEKSKKIDTIIDFKLMGIPLDYEEINRRYNLKNTSDYKFGHKNIYPKSDY
DWNKYLKDLVIFYDSIIAEIKTDNVHIFPIAQIPLLVSLGYLMQNDSPNIKIYQYSENEE
SWVFDEKDDNISVKENFINGSNDILAVALEVSSEVKQEDINQVIEKEYDLLSFKVDSPRL
GYLNYRNDVLRVKNIIKNKLDSIYSKYEEIHLFIAAPAGMCIEIGRIIRESMYPDTYTYN
YNRNDGIHYKKVCNLKTLRNNQ
>A0A4P6Q667|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomonospora litoralis|TrEMBL
MITLAHISDLHVDGGSRARERVEQVMAYLDAVADSVDALVVTGDLTENGTVGELEEARAL
LSGRLPAVICPGNHDVVEGRAPFRRVMLGSEGGEKGDPGEAPVNAVHRADGGAVVLCDST
VPSEDGGLLSEETLDWLEDTLADLRQTPVVLGFHHHPVKLHTPYVDHIAMQGADRLSVLL
ARHPQVAGLLCGHAHTAAATAFAQRPLLVAPGTVSVAPLPWEDAEQVYAAHPPALAFHIL
DDEGRMTTHFRTAPAGRT
>A0A378Z9T5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pandoraea pulmonicola|TrEMBL
MLFAQISDLHIKRPGKLAYRRVDTAAYLERCVARLNTLVPRPDFVVLTGDLVDFGAREEY
EHLRRLLTPLRIPYYLVIGNHDGRDALREVFPEHAYLGRPGDFVQYAAMFGPLRLVALDT
QNPPNGGGKLCDERLQWLDATLASDTTTPTVIAMHHPPFACGIEHMDVQALDAADARKLA
AIVRRHDNVERLICGHVHRSIHTRFAGTIASVCPSPAHQVALDLREAGPSAWVLDPPAFQ
LHRFTSQTGLVSHLAFVDDAGGSHPFYDASGALID
>A0A485MP00|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lynx pardinus|TrEMBL
MANPVPVQRSHLQVPILRLRYMVKQLENGEVNIEELKKNLEYTASLLEAVYIDETRQILD
TEDELQELRSDAVPSEVRDWLASTFTQQARAKGRRAEEKPKFRSIVHAVQAGIFVERMFR
RTYTSVGPTYSTVVLNCLKNLDLWCFDVFSLNRAADDHALRTIVFELLTRHNLISRFKIP
TVFLMTFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIEVLAIVFAA
AIHDYEHTGTTNSFHIQTKSECAILYNDRSVLENHHISSVFRMMQDDEMNIFINLTKDEF
VELRALVIEMVLATDMSCHFQQVKCMKTALQQLERIDKSKALSLLLHAADISHPTKQWSV
HSRWTKALMEEFFRQVAWCLHPPLPFSPLCSPGSHSTSRSSCSYLQLLT
>A0A0S4I7P9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. URMO17WK12:I11|TrEMBL
MPHSNPAGTVNVVHLTDAHLFASPEGSMLGLNTRDSLRHVVQQALREQHDTHLLVCTGDL
SQDASVASYAAFEQLTAGFAAPARWLPGNHDEAQVMAQVAPELVQPVTDIGVWRIVMLDT
AVPGAAHGWLQDAQLSVLEAALRTAGERHCLVCLHHQPVDIGCAWIAPIGLRNADALFAV
LDRHPQVRALLWGHVHQEWDQWRGDLRLLATPSTCIQFAPGSEDFEVSQQHPGYRWIRLH
ADGTVDTGVQRALDFEVRLDFDSPGY
>A0A379J3B8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas fluorescens|TrEMBL
MPSVSIVNPDAPALLVQLSDSHLFAEADGTLLGMNTRDSLQRVIDLVRAQQPQIDLLLAT
GDLSQDGTLASYQLFRELSQQVGAPARWIPGNHDEPQVMAEATMGSALLEPVVDVGNWRV
IMLDSAVPGSVPGYLADVQLQLLAQALSEAPGRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERHGVRLLASPSTCIQFTPGSEDFNVSEQAPGYR
WLRLHADGRLETGVERVQGFAFTVDYASNGY
>A0A0R3RKF8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Elaeophora elaphi|TrEMBL
LIVTPFAQILASLRNVRNNLILIANIPPDESRQRPVPKRPPLHSTALPTDVIQCGQDTLD
ELDWCLDQLETIQTHRSVSDMASSKFRKMLNKELIHFAESSKSGTQISQFLINTYMDKDD
DEVSQNLRVPDETASTSSLDNVSISLLGKAKTAAMSRIIGIRKLKSPRGGHIPEFGVDGH
KELEIYMQKLDEWGPNIFKIQEYSKGHSLTSITFTIMEKRGLLKTFEIPSGILLNYLLHL
EHHYRDNPYHNQVHAADVTQSVNVLISSPALQNVFSELEVLASIFAGAIHDVDHPGFTNH
YLINTNSELAIMYNDESVLEQHHLAVAFKLLQDSNCNFIVSLNKKQRQLFRKLTIEMPTK
LNFHLI
>A0A240CB30|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serratia ficaria|TrEMBL
MESLFRLPVASGNTVRILQITDTHLFAGENETLLGINTYRSYHAVLDAVQAQRREVDLIV
ATGDLAQDHSQAAYRHFAEGIARLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKHVLLGD
KWQVLLLDS
>A0A0F2C675|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium sp. SA39|TrEMBL
MILTEHPRPSHVFVHISDTHLPRERSPLYGSGADADANLELMLSRLVDSGIRPDALLLTG
DMADRGDASAYVRLRVLIGPAAEALGCEVVWAAGNHDDRGAMRAELGLGPAVSGTEGADA
SAADPITEVRWFGGMRVIVVDSTVPGAHWGEVPSSQLSWLEGELSTAAPEGTLLLMHHPP
LPTVLDLAVTVELRGQGPLAQVLRGSDVRGILSGHVHHPSFGTFAGVPVAVASSSAYGQD
LAQPVGATRGQDAAQGYNLVHVYDDTIVHSAVSLAAGPDVGEPVAADEVLRRIERRGVGW
RERV
>A0A380QRN2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Yersinia ruckeri|TrEMBL
MLCGHIHQELDLDWYGKRLLASPSTCVQFKPHCTNFTLDTVAPGWRYLDLLPDGTLETEV
RRLDSDEFNPNMDADGY
>A0A0U5BBQ8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acetobacter senegalensis|TrEMBL
MSFTKSIACLLGVALAGNAFWAQPSWSENAPSPASARTGFDILVLGARGGVQDGNLSAYM
ISPHGDHRAILCDAGTVVNGLNEADHLGKLTDFSKSNQTELTPAGYVLHHVIQGYLISHA
HLDHIAGLAISAPDDTPKPLYALQSTLDDLSQYVFNWHIWPNFSDHGNAPFLKTYTYQPL
IPTHSQPLQNTAMNVTAWPLSHGPVTSTAFLIKSGSDALLYLGDTGPDPVEKTHKLQTLW
RAVASDVQKHQLKAIIMEASYDNSRPDNVLFGHLTPHWVLKSLHDLAQETGDATSLQGLT
VVISHIKYTLNTGAKIQETIKRQLDTENDLGVNFVIAEQGLRLHVH
>Q7NZT6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)|TrEMBL
MRIAQLTDLHLFADRQGRLLGRDTHAALDGVLAALRTVEGVEAVLLTGDVSQDESEASYH
LAAEALAALGVPVHWIAGNHDDRAAMTRVFAGYAFLRPLETLALGGWTFIGVDSCVAGQD
GGRLSDAGLDRLRRLLDEAGDGPAAVVLHHHPLAVGTPLLDDCMLAPASPFWRIAAASAA
LKLAICGHVHGEHSIAYRGKMLEVGPATCFQWRRDACDIEIDDRHGYRLFDFDGDGYLVR
TVFV
>U6F1L8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactobacillus helveticus CIRM-BIA 951|TrEMBL
MHHNLYAHNPAVNKGYVVDDAVELRRLCSRYNVKLAFTRHINAQNIMDPQETTPTTEVVT
SSFCSNDQGYGVVRVHSRHITYVRRNFDMTRYLTDQEKRKLYFRTLP
>A0A2N7RDM9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. AD21|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEADGTLLGMNTRESLQKVIEQVLRQQPRIDLILAT
GDLSQDGTLESYQQFREMTAQIDAPARWIPGNHDEPQIMAQAAVQSALLESVVDVGNWRV
TLLDSAVPGSVPGYLQDDQLQLLARSLSEAPERHHLVCFHHHPVPVGCAWAEPIGLRNPE
AFFDVLDRFPQARAVLWGHVHQEIDRERNGVRLMASPSTCIQFEPNSHDFKVGEQAPGYR
WLRLLPDGRLETGVERVTDFEFTVDYGSNGY
>A0A484XGM0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|plant metagenome|TrEMBL
MKFIHLTDTHLVADGGELYGTNPKQRLRQAIAHLLARQPDAEAVVVTGDLTHHGHAQAYA
HLRECLSALTLPVYPILGNHDSRVVFKEYFPDVAQDEHGFIQYSVDFGSHLALFLDTNEP
GVHWGVYCETRAAWLRARLAETDRPVLLFMHHPFFPIGIPSMDFLSLRDPAPLLAAIAGH
EARIRHVFFGHIHRPICGQYRGMGYSTLRGTNHQVALDLHGSAQCIIGSHEQPQYAVVQV
DAEQLLIHVEDYLDCDRQFLLHEMRDGAAGLK
>F0HT29|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactobacillus delbrueckii subsp. lactis DSM 20072|TrEMBL
MLMKTITDSERPDFWLISDPHLIADDLHDFGARFKKMRQTSAGKDIAYQDLALRAFVRKV
VRAKPAALIITGDLTFNGARRSAERLGEIFAPLKEAGIALLVIPGNHDIYDGWARSFSGS
EERRVAQISPADWKEIFSASYDLAASQEPGSLSYSVNLNPHWRLLLLDSNLYSSKFSCTH
PMTSGAIDDGERRWLSQELVEAKRLGQDVLFFMHHNLYSHNSVVHDGFKLNNAGEIVQLL
SQYPVRCTFSGHIHAQHIMSGWVPVPEVVSSCFAESDQGYGIVELTANSLSYRRHAFDID
NFLTAEEKKLPPFADFHAYLKEVFDRSNNLLLRQHLLKGAAKDLPEAAEMLKKMHWDFFT
GQSYKSEAEIAAIYESSAYRTLLAAMPSMKSYISSLYESTQSSQKLDLTW
>A0A069B8S3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Burkholderia pseudomallei|TrEMBL
MPNPIQPLKRRDFLRLAACGGGVAFASALPGWSFAANAGADFFFVQLSDAHWGFTGPAIN
PDARGTLPKAIEAVNALPVAPDFVMFTGDLTHTTDDPAERRARMRQFQSIVAQLRAKPLH
LMPGEHDASLDAGAAYREIFGDTHYAFDHKGVHFVVVDNVSDPAGRVGDAQIEWLARDLA
RQPKDARIVVFTHRPLFDLAPQWDWATRDGAKVVDVLMPYPNVTVFYGHIHQEHHAMTGH
IAHHAARSLMFPLPAPGSQDKRLPVPWDAAAPYRGLGWREVRVGDAARAPALTEMPVAAP
QPQPRA
>A0A183HGI9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Onchocerca flexuosa|TrEMBL
MTCLRKQISPKRGLLKTFEIPSGILLNYLFHLEHHYRDNPYHNQIHAADVTQSVNVLISS
PALQNVFSELEVLASIFAGAIHDVDHPGFTNHYLINTNSELAIMYNDESVLEQHHLAVAF
KLLQDPNCNFIVSLSKKQRQLFRKLTIEMHIDM
>B7P0N3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ixodes scapularis|TrEMBL
MADRVGASVDGEVPSDQSQETASKSSRNTQWVKLNVGGTCFLTTRTTLCRDPKSFLYRLC
QEDPELHSDKDESGAYLIDRDPTYFGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITEL
IKLVKRHIQERNRDHRSRDARKHVYRVLQCHEDELTQMVSTMSDGWRFEQLINIGSSYNY
GNDDHAEFLCVVSREYPSSTSHTTDREFEPTDRAQWALGFGSKTQKVLDPRFANNASSLS
RSSSSRRLPACEESRTERRTGEGAAMAPVAVVTSHSLLPKHHHYLRQGSLLAYFAEGGFN
VSGLPQPQDRRAASPGT
>A0A4U9HUS3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Leclercia adecarboxylata|TrEMBL
MLIAQVSDIHAAPDNDHLARFDRVLRWLRQLQPDALVLSGDLTDNDWLEGYQQIVARLAE
EHYPSLILPGNSDNRRLMRAVWRDETGANDTCDGALHAVLEVGGLRLMGLDTTVEGHDHG
SVTAHLGWLEKQLNRADVLPSILFLHHHVFACGIPTLDQTLCNGLDRLEALIHRAATRPL
AMASGHVHRPVAGMFAGIPAHICASVCPANPVWFGSDRVPPAEDAPGLMIHRYVNGALTS
HHVSV
>V8NFA1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ophiophagus hannah|TrEMBL
MTQDKREKIGIKTNSNQAKTKTCDQRTKKKLSTTLLSLLDTEDELSSIRWDSVPMDVKEW
LTGTFARKKEAYRLQPDEITSFRSISYALENGVVKYIADGRKRRKKVEKIPSAGLEFRTA
TTSMGMAYKLDVIQAMKTIDKWDFNVFTLDEAAEGHCLKFMMCEIFTKYDLLKRFQIPIT
ILISFAKALEAGYSKHKNPYHNSLHAADVTQTVHAIMIHTGMLQWFTDLEILAIFFSSII
HDYEHTGTTNHFHIETRDLRRMVINVVLSTDMSHHFQQMKTMKHISQCLQLADRTHKDKI
MSFLVHIADISHPAKPWELHHRWSEALLEEFFEQGDKEAEMGLPISSLCDRKTTNIAESQ
I
>A0A1V5W053|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bacteroidetes bacterium ADurb.Bin217|TrEMBL
MITILHITDLHIPDTNESAYDIDVHQNLLNTIQAMNDEAYGMVLVTGDIAYKQANFRSYE
YVKQAFQTFYKPLYVLAGNHDTTEMLAQFFPNSFPNKQTNYRIPNPEITLLCMDSSASVI
TDSQVEWLQAELSQSKQVVLFVHHPILPTPVTYMESKYSLRRRESVLQVLEQHPYPIHIF
CGHFHTDDVVTHKHITQYITPSILYQVNKQSTTFDIGSEAYGYRKICIDSQHVVTEVVWL
>A0A1X6YHK2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseovarius gaetbuli|TrEMBL
MTRILQLSDTHVTVPPHRVSGELETFALLGSAITRILADLDGLGPIDAVVVTGDLTDLGD
AESYHLLRRQVERLGLPWFAIPGNHDLRAPMRAALADLDYLPAEGRLNWIRDFDDLRLIG
LDTLIEGQGGGTLDGDTLAFLDNALQGRADVPALVALHHPPFASGIAFMDRIALDATAPL
AEILGRARSEVRLIAGHVHNTFIGQVGPCIALTSAAISSSFPVDFRANAPVGFTTAPGGY
MLHDWRDGFQSTCVSLASGSGPHPF
>S7V394|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii (strain ATCC 50853 / GT1)|TrEMBL
MNASSKSMRIGFPNGSPGVGDPGMPSPVLPLCQTASHALGNARSQASEGRTDGASDRSIS
ELEKESCQRGHRLEAREASEILAAESAQEEHRSCARKPRASRVEVDTLAESPERPSQAYV
PTESLGLGPRRTVPLCSAGSSASAGSWISSGDSVREETRQIRGRDAANKCSTAELSVSVE
RSCGHHEGTDTATQCVAARPEALCAAFLPAPSPGVSVDSAAAAVGPHCAAEVPVGADRRR
RLFAAPFSALPQTDACSRGSATPPSLFSRQPFDTVRSSSSLRDGGNAWTRLLDGCSAHPT
SSSSSVSPPVLGSIRTLQQSLPSSDDDTTSARTDTSLTPAKQVWLLPLHGHSLSQSSSSS
FREFRVTLGSLTGFRSSDSRTSASGSERRRSKSRGKPQGRSGSLGRDNRRKSELSGRDES
LSWIARRWWTRDEDSRWSDSRVRGSVALRAESTSDSRCENNSCATWLCRVVRRLPVAPAQ
TFCDEDEKRYTEGVLRFSRRRTIPVAVAVVIVSFLYTVPFVLHALQEFVQTPSADRKVFV
FFSSRAPPRSPVAAGAAHDAQLDVSAADSALQDVGGKDAFFVVASLVFWLLSLASVLVFA
FFAVFGALFVRIEKILCVLTAVNFSALALAECFQALRISSCPPSLFPEQAAAEGGSDADR
CAQVHSGLTPELLIIQTFFLIVLDFAFCVRLRISQWLHLCAVSLLLSLAFVYSILLPLPA
YLIASLWGQAVIGGFVLGSLHLAALTLETERRRVFLHFEVAKARVAELQERAQTDKHHGK
VAVFGLIHTLKQMDACMNELQNLAPEAADVLFQLDALRVQCLDIATSSENFYAVNMNALP
TDVRDLLQLETRNAFDGTTFRDTQVLLRDSLSPRKGVLLDLSLGPACGGVSRERRASCSA
AVSSTSSRESDRREAIARDPDLTETERRDAERRGMERKATDDRQKKARFLVVPQLVEHEL
LCHVGILWSLDLFKLDKECNGNALLHVGYQLLAPLLAAGYLTCSREVVLDFLYSLQCLYI
DTPYHNQLHAASVAHLAFSICHFLDLFAPLENAPGDAAASQPVFAQYLSLAIAALGHDAG
HPGRSNAFLVQTSSTLSVVYNDRSILENYHACLTFYTLSHRKSNIFRGKTVTQYRDVRKK
AIELILSTDMSLHFEFLTRVAARRENPDFNFVDREEDRALVLSLAIKVADLGHCALDWEA
HTLWSARLKEEFLAQGDEELRLGLPVSPLCDRTQQGQLARSQANFIEFLFLPLAQHLAAV
APDDRFEATVVTRARQNISMWEGAQDEVDQASAK
>A0A377VA21|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MLHPASGYRGNHDFQPAMYSTLQEAGISPAKRVFLGDRWQILLLDSQVFGVPHGELSDFQ
LEWLEHKLAEAPERYTLLLLHHHPLPAGCSWLDQHSLRNAGALDSALSAWPRVKHLLCGP
YSSGTGSRLEWPAHDGDAVDLRPVLNRTVPISLWIPVSPGWRWLELHPDGTLTTEVCRLE
GAAFHPDIASEGY
>A0A2G8Y6G5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii COUG|TrEMBL
PECNIFTHLPPEDFQIVRNRMIDLILATDMKMHFEMVSKFRLRRNSPDFCRTNDDDVWML
LRMCIKGGDLSHGLLSWDSHVSWSYRAASEFYEQGDLELAQ
>A0A654DYL3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sphingobacterium multivorum|TrEMBL
MNPSYNNGWVFSLIIMKKLALSIFTFLVTMTCQAQHFDLVPLGIYGGEQEDNLSAYLVGT
PRDTAFLCLDAGTINTGIRKAIVLKSLNGSVETILHNQIKGYFISHGHLDHLSGLIINSP
ADSKKNIFAIDPVLQILQNHYFITDTWINFGDQGQKPILGKYHYNSLQEGLEMQVPNTAL
SLTAYELSHVNPYKSSAALVRHDNHYLLYLGDTGADRVEKSDQLDKLWNKITPLIKNKQL
NSILIEVSFPNNQPENLLFGHLTPNLLLEELVKLKEKTGLKNLEGLSIVVTHRKPTGNNP
EIIKNELLNNNPLKINYVFPEQGKKISLN
>A0A086LRY2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii RUB|TrEMBL
MAELPPRRRRSSLIRLEENCDSLSGFSTRPSRTAPVHAVSPRASPLREEAAVSPTKNRDQ
EGLSPLQASPSTNRVLNTLWDPAGRETEPFGDLVEKGRTRREREEQDRRQSEGERRPYST
GRKTPEDGGDGCYTAHAGYSPGSLFASPGLPFYNEREQERRRRASRRIGAVGVDAQFYGS
IGQQLRALQVACDRQKAEALRAPVEVACSAEASMISFGRSVAGTLSAALGCPLVFVCAYD
KETDELYCCFTSLPLGLLCPPSSPDCARSRSPASGGALALGVDSEETAPAGAARRDVETL
VSRESSLQTSSRVSSPLRLPPSHLARVPSETAAECISSHDHESSGGVFAGAYPQLSPALV
SVPPGPSAYLSSLPAQLRLASARQMGLVSSTRRDSMHVGASRLAAAHAPAETERMQELLE
APTWEAKRENAEGEEKRTDPEAVETEEVTNTGDEEANRGHEKTRGMLNRVQDKWKAQKET
KKEDASGRPDNRQLHAMEGGTTKAALSCVWPARKEKQRSASEIQQRGSMSSVDLEDAEAD
GGTYEGRQHTETGAEEEGSVLCGRLDSAEEVLVHQLHQFLRWRFVDDRRASNTASFAWSA
PPEPQTVSPRKAERHSIPCPSGRVAASRTSSLAPLPSPARQSGLAGAMMERHRKGPPSPF
HIPRWECVARATSVQRLEAEDPGTRTRCGEGRAASDSPRRQARVCESPLASPEEELPVPL
RYVSDPVSCDDSFDSRSLEGPEVLVLSPHVGCIGELFQNASARTTQTFLYNPESDAIIWP
RAGLPSPPPARSLPQSSSVPLETNACGRGVSGSSSPTPSSPSLTSSSASSAAASFVSMRE
PADQLAAQESDFRANDFQEGAGVLEGATAGVERAIDAGCASCSPLRLLVRQLRDQTGSRL
WELMEESRIDYSSPSERKRGPVADGPFGRRSEAPSSSSLPRSLAPHTSHAASLSSLPAES
TLPRSARKSPSSSSSSAASAERAPRRSAPPVPRSPSVSFSLPEAKETISGVDAGAAVPGE
LATRAARPNFPMGLLVCVQPLHADCQGQEELIDEVADRIEQLLLSVLYVEWLKRERTKKA
LQLELHRSVFQEALNPIKTVERFLSLIHTTLGVEQAAFFIVDAQNNSFVCLGGAL
>A0A086M847|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii RUB|TrEMBL
PVASVVGIVCAFLQMNRRSLLALTYNDNSVLEQFHSSVAFFLLHHHHLLLPSSPHCSTLE
RTRKRRSANHEAAAPSRKNEAGTQISTREASEAGNLELVGEDAAEQERGESVCAESLCDR
IEREEYYRNFRKEVIELIVHTDMTKHFSLLALFKVKRQTGGLDIVNNDEDRSMLLKMLLK
AADIGHATKAFDFHFFLSCCLIEEFHRQGDEEKKRGMVISPLCDRQQELRQIFSSQAGFL
QVVCLDFFSELADVARDLEHAQTLQLQSASAGPEGASGPRPASSGSRSHQRRDCAASRAS
GEEGRNFEASKDRQLVSRSFSSSASVPRLSSRKGFRRCLSTAEQPQPPLPSLTPSSPCRF
ALSSSAAYASGSLPSLLLSGAQSEDAGNRRAPPRLHPFRPLSGRGKTEPSSTALVREALP
PQAASAAAAVSCVCHQASVTGTSVFKRPCVGDIGSPPGLQGRLPAEETKAAAADSATGID
PASAGEKRRVFSSGVSHPFALPHGGPESRGSEKSGNACMRSLSSFFRGPKARKEDTDDDA
RARQKRSQTLPSSLSLVSASRCNGAQAFANRLPVRHCLDAEEPGGGRGGQDAPTGHRRIL
SRGGSLPPNYRSSEGDQGGPKSQGESAGTIGALRAEPTRTGETSDGKLRGTEAATGAKNR
NAWSCPCETEESAATEGRESKDREAEAEAEEEERLCQGDFCEFCRNNSWSISRAASQHIA
SSTASAHSSSLLEACVTQIQRNKHAWEAMAEEQREPPRLLPADLLFGPFPRDGVGGLVRR
HLKRWSTLSPS
>A0A011QMS0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Accumulibacter sp. BA-94|TrEMBL
MRIVQLSDLHLSSQPLYGVVDTLAALQLALQRLAAMPAPDLLLLTGDLTSAGRHEEYALL
RSLLAGLPLPCALLPGNHDDRDNLRAAFSEQAWAPPPLCCQRIDLADGTLLLLDAIVPGE
EWGEVAARQIDWLESACPQRRPVLLALHHPPFCVGIAGMDRIRCRGDALLAAWLARHEQV
EALLCGHVHRFVSTTFAGRPAIVAPSPAHQIALQDGPLAYTLEPGGFLLHDWLPGWRLCS
HYVPVVVSPTQCYGDG
>A0A2P9IW36|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Actinomadura parvosata subsp. kistnae|TrEMBL
MTLLLAQISDLHLDGTDRATRRATRVMDYLRALPRPVDALLVTGDIADHGEEAEYEQAAD
ILAAPFPVLTCPGNHDARPAYRKALLRLPAAHGPVNQVHHIAGTAILMCDSTIPGHDEGL
LDPETLAWMRTTLDGLAPDTPALIAFHQPPVELHHPLPDSGRLREPDALAALLHAHPQVV
AVLTGHAHTAAASTFAGRPLIVGPAVTWTLRLPWEGDRPADREQPPGLAFHVLDDDRRLT
THYRVVLPA
>A0A085FKM9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Massilia sp. LC238|TrEMBL
MLIAQVTDLHLHADPGHPNLARFNRVLDHLLSLQPQPGLLVLSGDLADDGAPESYRHLQG
ALARWPRPLRFALGNHDHRGHFRAVFGESHDADGFVQGRAEFGGLEVVVLDSLEQGRHGG
AFCEARAAWLRQAVQDSRGAPLLVFLHHPPVDVGIPWIDPGPGQDWIARLDAALQGAQVA
GICTGHVHLAGMFPWRGRQVVTCPSSSSDLSLAFSPMAAGQPDGRALVEQGEPAFALHRW
EDGALATFFARCPQRLLARWDAGTQPMVAAMLAEKQA
>A0A086L5C9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii FOU|TrEMBL
MAAHSPYLGRPGTFSAPDECWNEERVPSGISPADTIREIVLFQALRNAERWSARAHVLET
KTGKTPAVSVSGFGSADASEGQRAIGSKRATPGKEDSTKSSKDSPRSAFASSPPHAHGPG
ASTPPGPQSVCGASFWTQRRLLVRHKTYSPARFGISAEDERDEGEDRLSRDEGETGALAG
SPGFALGKRDRMRERKLKPPRRRSWMTVTENRKRREQEEQRRDDRSRVKENVLRGILKRE
KEEKKSNEGTRDGVRSSTCRHANPEHRTNREDRKGKTSGNHEMDENADRSRMSGTRKPGN
ETWGREKDLEDHQPHTCEMLPQENEITDIAEETERGRAVESAGTLSQKQARETKKREASK
EKGKGARRHAGESMQTSQMSLETELLHVEKRVCETV
>W6UMR0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Echinococcus granulosus|TrEMBL
MKMRYNSEKRRMEVGYSPDCVEALSSSSAESMDCGEATNERRDRNDDQSYESEFPSLSNS
SVAFYAKRRLSIEGLPLPGSTDSTFACLLRLRKIVKLTEQNKITKSVLIENLTYALQVVE
KTYIEETKRLRDEDDELSETACSEVPDEVRNWLASTFTRNPSGGRRVAKPRFRSVVNAIR
AGIVVERIYRRMSSCTCLILPPNVVLLLKSGLDEWNFNVFEFNEVSADHALKYVGFELLH
KYNLISKFQIDNSRLENLLLRLEIGYGKYKNPYHNLIHASDVAQTCHVILTTSKLRDYLT
DLDIFAVIYAALIHDFEHTGTTNNFHIQTQTELAMLYNDRNVLENFHVSAVFRITQESEF
NIFENMPKEQYQ
>A0A1J5R9D1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|mine drainage metagenome|TrEMBL
MRIQLASDLHLEFLAQLFPGETTLAPAPGADVLVLAGDIGNGRLATALFANWPVPVVYVA
GNHEFYGRDWMATRQALRDTAQGTAVHVLDNSAVVLGGVRFLGSTLWTDYRYPCALGQRE
LMNLAGISLNDHRRILADDGLFTPDMALQEHLRSRAWLQEQLALQHAGKTVVVTHHGPSL
LSVHPRYSANPINAAFVSDLGELMRGVPLWLHGHVHDSFDYGLNGCRVVANPRGYPRNRG
EVPSMDALVFENPAYQPACVITV
>A0A137Y612|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acinetobacter venetianus|TrEMBL
MTFQVSTLSQKDFVMVQITDTHLLEYPHLEFVGMQPEQSFRAVIDLMRQQHSEIDLIVHT
GDLAQNPTPVTYHRYLEHMNTLGIPFFHTPGNHDDVAYFPFHETEPTKPTVVEVGNWRII
LLNSAQPERIDGKIADIQLQQLTQLLTELKDCYVIIACHHHPFAMQSAWIDQHKLKNSSD
LLETIEPFNNVKAIVCGHVHQDSINTWQGVEFLSTPSTCIQFKPKSDKFALDEEHPGYRY
IRLKSNGEIETQVYRLSNSQRMSSSEVLGYD
>A0A378X236|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nocardia africana|TrEMBL
MTENDPQHTDPRDPHAMTRRQLLRHSAWFGAAVGLTVVGGEVISHVAGAAPATSDRPTLR
FAQISDSHIGFQGTANANVTDTFTEAIDQVNALGYTPDFVIHTGDLTHLATPAQFDQVRQ
MMSGLRAPHIFTVPGEHDSADDGGQRYREVFGKGTRGDGWYSFDIAGVHVIGLVNTLHAQ
NLGHLGQDQIDFVRTDVAGLSADTPIIVFSHIPLFAMYPQWGWGTDDAAHVLSLLRRFSS
VTCLNGHVHQLFTKTDGNITFFSGTTTAYPLPHPGDGPAPKPVTLPAGKLHDALGIREVS
YQQGRQMLAIKEQTLR
>L0AYT0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Theileria equi strain WA|TrEMBL
MLNQGDSKGRLDLANRADLPISSDLVPVKLSTTSTTPETINVDEFDVMVNDLRSIFLCWL
KKTQNGLKAQRDSINRETEELQKEKEAFVQRMKQERAIEAEKLAEDRRRQNAEIASQLKQ
VQIEREDSRRRIEEDLCKLEHERDVFRKYMQLETEKFRQKVELFEQEKRKVVDTKIASET
MVDINVGGVVFETSRHTLTKQESSYLNGLLSGRYEIGRDRQGRIFIDRDYELFRIILNFL
RNPASLPVPRDLTESSMILNEAAYYRVKFSPYPLVLCYGGHNGHEHLKSMELLDQETKCW
RNCSPMRTERIYFGSGVLNNFLYVFGGQNLDYKALCDVEMYDRLRDSWHAAASLKQPRRN
NGGISFENRLFCVGGFDGMNILDSVESYDVRMKNWIPMATLKVPRSSAMVTHQNGSIYAI
GGTNGERLKSVERYDLRKNEWELITNGLLEVRSAGSACNYHNEVFIVGGIDNTQNIHSSF
ETWDSKNQTSSFLKDAPVPVMDAAMVSTDLSILMTGGQNTSVLDSTYFYQPETDVWTAGP
PLIMPRYGHCTTVLDF
>A0A1M7Z200|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio quintilis|TrEMBL
MLIAQLTDLHIREGGKPAYRKVDTLACLREAVNHINALQPRPDLVVVTGDLGDYGTPEEY
AVILPELQRLQPAIQVIPGNHDHRGCLREALAELTTFDHPHYCNFIRECGGYVLVGLDTS
VIGQPYGLLSDETLIWLDQVLQTHADRPVLLFMHHPPMAVGLNHMDVQKLQNDDQLYDVL
TWYSHVKGIVTGHLHRPVFALWHDLPVWVGPAHNHAVTLDLDPQAPSSFSLESRAIQLFA
LKPEGIVSHLSYLGAGEGPFPFFDENHQLIC
>A0A377N7W0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ewingella americana|TrEMBL
MFLAQISDMHFRSQGRKLYDFIDVNACNAEVVNQLNALEERPDAVVITGDIVNCGLPAEY
LVARRTLQNLHYPLYIIPGNHDDKAQFLEALHPLCPELGHDPQNMRYAVDDFDMRLLFID
SSLAGESKGFLTPETLSWLEEQLKAGGDKPTAVFMHHPPVKVGSAQMDSISCENGDELLA
LIDRFPSLCRVFCGHTHRLIFTQYRQAIITTIPGTVHQVPYYHHNPAPFYNLEPAACVMH
RLVEKTGLVSYLHPLSQYPGPYLYDATISCPVDDE
>A0A8C6X140|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Naja naja|TrEMBL
KDVIKLGLTCLENTKYVHMLGKHNRQTRGSLWCPMLLQRSSYPEYLYIYKNLDFCRSLLD
TEDELSSIRWDSVPMDVKEWLTGTFARKKEAYRLQPDEITSFRSISYALENGVVVERQFR
TATTSMGTAYKLEVIQAMKMIDRWDFNVFTLDEAAEGHCLKFMMCEIFAKYELLKRFQIP
ITILISFAKALEAGYSKHKNPYHNSLHAADVTQTVHAIMIHTGMLQWFSDLEILAIFFSS
IIHDYEHTGTTNHFHIETRSKAALLYNDRSVLENHHLSAAFRLLQDKDTNILGYLYIDMY
MSELIGKDSSGTHKDKIMSFLVHIADISHPAKPWELHHRWSEALLEEFFEQGDKEAEMGL
PISSLCDRKTTNIAESQIGEAHLKGGRQSLFPPHTLFTSDIRSKTTIRTKNDSLFLR
>M5B6J0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clavibacter michiganensis subsp. nebraskensis NCPPB 2581|TrEMBL
MHALPPGSLRLVHLSDTHLLRDGGLHQGVVDTGAALERVLVEADRVPGVRLLVGSGDLSE
DGTPESYALLRERLVPWTSSRGAALVLAPGNHDIRSAFRLVLGDGHGGPGTDDGRDPAAV
PPVDGVTIVDGWRIATLDTSVPGKGYGALREQQLDGLRELLATPAEHGTVLVLHHPPVPA
PTTLHESLALQGPERLAELVRGSDVRVILSGHYHHHIVGSLAGVPVLVAPGVANETDVAA
EPGTERIVRGSGFLVVDVRPDGGVTSVEVRAHAEGDGDEVALLDAELVQRITVEAGAPVL
P
>A0A146ANC0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bordetella trematum|TrEMBL
MSAISFDIKTDIGYGVIFPSPVEPPLFPTASHMARRDQPALLLQLTDPHLMADPQARLRD
VCTDASLQAVLALIRQQEARPDLMLLTGDLSQDGSVASYQRLRALLGEADYPVRCLPGNH
DDAAVLRQTLAGWVSPVFDLPGWRVVMLDSTVAGEDLGHVSAGQLDMLDEALRGAGSRHV
LVALHHNLARVDGNWHDPMMVTNAAEVFARLRAHPLARVALWGHIHQEFDCRHYHLRLLG
TPSTCFQFRLENGRHAIDPATPGYRWIKLYADGSIATGVRRLADWARLQPGAVPALDVA
>A0A672NU82|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sinocyclocheilus grahami|TrEMBL
SVPMEVRDWLASTFTRKMGVVRRRPEEKPRFRSIVHAVQAGIFVERYLFCCYLRVGLKQH
EMSSLVSFVEALEMGYSKHRNPYHNLIHAADVAQTAHYLMLHTGIMHWLSELEILAMVFA
AAIHDFEHTGTTNNFHIQTRSEVAILYNDRSVLENHHVSAAYRLMQEDEMNILVNLSKDD
WRYLRTLVIEMVMSTDMSCHFQQIKTMRNGDKEAELGLPFSPLCDRKATMIAQSQIGFID
FIVEPTFSVLVDTTEKIISPLIEEAVKSGGVRRSSLTGRGSAAVVESVQRHSGRGSNDEQ
GGTTDYSLGGIELKRVRHLLSEIIQNNKERWKELSVKGLHTSFVNIKIRNIKIRILGKLS
KKLWKTQMEEWELL
>A0A8D1EDS4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sus scrofa|TrEMBL
MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD
LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR
SEEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS
GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV
HYLLYKTGVAVSTDKNAEIALKMGWSDPAILYNDRSVLENHHLSAAYRLLQEDEEMNILI
NLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPEAIEKPKALSLMLHTADISH
PAKAWELHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKSTMVAQSQVGFIDFIVEPTF
TVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNNISSSDAKRSTVKSSGSEGSAPINNSVI
PVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKARLAAEEKQKEMEAKSQAEDG
AAGKAEKKASGEAKTHPVNGTRTNKSDNPRGKNPKAEKSAGEKQQNGDLKEGKNKTDKKD
QSSVGNDSKKADVDSGRADYIGMEYKSL
>W6M354|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Competibacter denitrificans Run_A_D11|TrEMBL
MPASTAVRIVQITDLHLKVEPGSRLWGADVDAGLHAVLADIRQRQPAADFVLATGDLVGD
EPQAYPRLRELLATLGKPVYCLPGNHDFPGPMQQVLSGGLVRRERYIAVGNWQIVLLDSS
FPGSPVGHLARGELGLLDTVLATNPDLHTLICLHHNPLPIGTGWLDTMTVSNGAVLFAVL
DRYPQVRAVLFGHIHSEFSSRRGDVHLLATPATSVQFKPNTPDPQVDDVPPGYRWLELYP
DGTVATGVKRVEWAAGRPT
>A0A090E7H1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mesorhizobium sp. ORS 3324|TrEMBL
MKIIQVTDVHLGRRGEIRFGANLNERLDRCIDHINARHGDAALCVFTGDLTESGETESYA
DLKTALGRLSVPYRLLPGNHDRRANLIAAFPENGSDGNGFVQSVFDTPQGRLVFLDSLAE
GRVTGELCDNRLAWLGARLAEAEGRSVYLFLHHPPVELGLAILDPLGLEQPQKLLDVLKR
HGNVRYIFFGHVHRDIAGTVAGIPFSAQRGLHARFMLHLTGDEVVEQAPPAYSIILIDGA
RVVIHSHDFLENWPLWSPATGERVR
>A0A422NSV7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Trypanosoma conorhini|TrEMBL
MKSHPSHIPVKRLDITPRERLLARFITQLRKRLSESATLDEFRAWVDEQAQALEAPLLEM
RPRQRGDAGNAVAVTPTSLESLSECGDEGVESGMYWGWGEQGNAFTRYPSMTEFFRVTSP
NNSARPRKNSSRITVASESTAGTSQPREKSLLTHSLKNVVHCEDTVTEKDVASILQLSSL
WAPSVFKRGVAKPLGRGKQGRDGETNPLESGGSVNQSCSLPPESVHDLLGLSPRTGAPPL
PTGISILDLSSPGELGDGMPAFSLDGRLPNQGPIFSRSTSRHSPVLRPTAQIQEALRGLG
VPFLEDVESANVNVLKYEERYGRNAYVYTCLNVLLRYNFSLQFGFHVGRLHCFYVNAAKC
IFAENPFHNIRHATDIVLAAHQFLRQPYVAENFTDEELFSFLFASTVMKLGHLGMSNAFL
VNVHHPYAALYGFLSPQQSVSVALGFVLFDSPECHFPTFVTAQEAAGDSTTSVWTPAKEV
DFEEMTSRLIMPTDEREHQVLLAQLQKVLQEGAGNVVRESHLMIILQNVLHAADFCYVFR
SPAVYRTAAAHAVAEIYQQEQTRLWFEENGLTRWPWCEANAAVCGERLTPPRSIKMDGSL
LSMEETQKYSGECQPKWASVNFSDMPNGLTPSDSSITPSAGHLSGPSGFSPLHHAKILQL
TVLEVVFVPFLFTLSPFVPDYWLTNAQSNLVWLGDLSADAFETDVTELLRRLEIGGPRLR
SVGPCGFEHQMLRRILSPLL
>A0A0A1HXL9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. SHC52|TrEMBL
MPSVSTLTTADPVLLVQLSDSHLFAEADTSLLGMNTRDSLRAVIDLVLKQQPNIDLMLAT
GDLSQDGTLQSYEAFRQMTARIDAPARWIPGNHDEPQVMLQAAVQSMLLDPVVDIGNWRI
TLLDSAVPGSVPGFLAEEQLILLANALSEAPERHHLVCLHHHPVSIGCEWMAPIGLRNPD
ALFAVLDRFPQVRAVLWGHVHQEVDQVREGVRLLASPSTCIQFEPGSVDFAVGEQAPGYR
WLRLLPDGRLETGVERVVGFEFVVDYGANGY
>I7KLT0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactobacillus pasteurii DSM 23907 = CRBIP 24.76|TrEMBL
MITSDLNTEIWVISDTHLIADSLHDNGQAFSRMQKTSQGKDLYYQETALAAFARMAEKKR
PAAIVVTGDVTFNGERVSAEKFAQIFSKMTTTKLLVVPGNHDIFDGWAREFHGKKQYYAG
EISPRFWKMIFNKCYRIAESEDDSSLAYSVKLNSQYLLLMLDSNYYGKEETTEAPHTRGG
INKEQLKWIEGQLKYASKENLRPIIFMHHNLYAHNPAVDRGYVLDNANELRRLCSRYNVK
LAFSGHIHAQNILGPQDMTPTTEIVTSSFGSNDQGYGVVRLHSRHITYIRKEFNMAAYLT
EKEKQDYTLLHFRDYLETLQLGTIAADLMQSDLKKNHNNLDLIRKMGKLFAKMNYNFYTG
YNHLSEAELSKIRSSEEYKVLIKQHPEYRLYLKTLYDTSSHSNLQARINY
>A0A6S6UMS2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Thiotrichaceae bacterium|TrEMBL
MMSDLPILKAVKLLQITDTHCYAADDSRLEWSDLELYPNKSLIRVLDHLTQLSGDYDALI
ISGDLVQEETVATYQRLHGILNDFPLPVYILPGNHDVPELMRSELSAQSERIHYVTHTAF
GRWHAVFVDTHLTGHPEGDISEEEFAELKRTLDELPLAEHAVIFMHHHPVPIGSPWMDHM
GLKQTEPFWSLLADFPQVRSVVFGHIHSEFSTEYPVTAERNIRVLGTPATCVQAKHNDEE
MQLDDTRPAWRELVLRPDGQVETAVSYLPN
>D4X695|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Achromobacter piechaudii ATCC 43553|TrEMBL
MPRVHSLARRHDAPAMLVQLTDSHLFGEPDTSMLGVNTDASLRAVLRQIEADGKRPDLLL
ATGDLSQDGEAAAYRRFAAILGQAGVLSGAQIRCLPGNHDLPAVMRQELAQWSAPVTDVG
AWRVVTLDTTVPGSNAGHLPDSQLDMLEAALADAPGRHTLIAMHHNPMQIDSHWHDSMMI
DNPQALFKRLTRWPQARVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNLA
PGYRWIKLYQDGSMATGVRRVQDALWHTALAPVNEQAA
>A0A139XM19|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii ARI|TrEMBL
MFDRRKHADFPKGQEGFLRFIIIPLYEEIAAVDTTDVVQTCCLQNAVANSERWRQLQSSP
EEFEAIDAKHQAIICVLKDRLEWRVQKNIAPTQRLLRASCAENQVRGSGVFFPTPECSGG
SGAPRASAPAEKRRESASASRDRDPGAADWKEETGNTAQALRERPPTEVAPQVDGEETCV
SDGVHERNRQDEGGGSEEGRRKAAGGETEKQGDDRKDLLHFESRLTH
>A0A1E1UZQ9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bosea sp. BIWAKO-01|TrEMBL
MPMIIEPRAGDAEDDASSTKKRSLIAIAGSMLGEINLPKLALAWVILALLPGFLLGLAPL
VATAWFSSMSGRIYALAGIGPLILLVLIAALGWFGFRPLFRAAERSFWSLNSLAVQPGYA
LCREGLRHLAERFLTAQASEDKRAGLRAATAIGAGLAAFFIAAGIAAFAWPATRWSGEIA
DLANPLRLVVPALANTVTVMSGYLAVASLAWGLADGLMDQPRDLGAYDEAPPSARKWRVV
HLSDIHVVGERYGFRIESGRAGPRGNERLAQVLERLDEIHAQEPLDFILITGDMTDAGRS
AEWAEFLDAMARHPALAERSFILPGNHDVNIVDRANPARLELPTSPGKRLRQMRTLSAMA
AIQGDRVRVVDQDRTGLGSTLSAALEPHRKTIAAFADAGSLRLSAGLANIWDDIFPMVLP
PAGEDGLGLVLLNSNAETHFSFTNALGLVSEEDIRAMLAILRQYPKARWVIALHHHPVEY
PKPAKAFSERIGTALINGSRFVRQLKPMSHRLVAMHGHRHVDWIGRCGPLKIVSAPSPVM
EATDDEATGFYIHTLAAAADGGLALLAPQRIEVAPRPDAGLSS
>A0A2C9JPD2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Biomphalaria glabrata|TrEMBL
EKGSSSISSSASLSATASDDTRKYRALLPRRLCEEDDELSEVEPDAVPTEVRDWLALTFT
RSMSNMKRRGEDKPRFRSVAHAIRAGIMVDSHRVIMDNKKGHHMVDNVRTEIRKSKEETI
IIKDSNIRFCFFYFQMLESFLFALENGYSKYKNPYHNLMHGADIAQTVHYVLSQSRLAQL
LTDLEVFATLIAALIHDYEHTGTTNNFHINTCSDVALLYNDRAVLENHHISAAFRLVREE
EHNILCNLSKEEYR
>A0A1J5NDC9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moorella thermoacetica|TrEMBL
MKKFVALLVAMVMAVAMLAAPVASFAAVTPKYDPGASAQPDHITLTWTQDPLTTQTITWR
TDTTVARGLVQYAKAADKASFPGKAFTVEATVQKFTSDQGDMNIHSATLNGLDPGTSYIY
RVGDGTHWSDIHTFTTEASNTHSFKFLIFGDSQSGDPLNPEYKPWQETIQNAFKANPDAK
FFVNVGDLVEQGQNYIHWNKWFEAAKGVIDTIPAMATQGNHETYNPPDGHSTKPIFWTTQ
FKLPRNGPEGLKGQVYSFDYGNVHIVMLDSQEEEEKGVAGDILAAQKAWLEKDLQDTDKP
WKLVFFHKTPYYNKANRTNEEIKAAFQPLFDKYHVDVVFNGHDHAIARTYPIASDKFVSS
PAQGTIYYVTGRSGNKYYHDLSAKVWDAFFYDPQDQPNYIVAELNGDKLTLKAVKQDGTP
IDTYTIDKASGLDTPQTVIPPKYNNTRLVVFGNMLQQPLLPVPPKQVNGQWYVPVRPFMQ
FLGGNVAWHEDGNVSIVYGKNKVQISSNSARATINGQEVNLPGNILLDKDYLFIPAAGLQ
TLFGFNYKYDAATNMLMFTR
>A0A031FM73|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium oleivorans|TrEMBL
MQSVSFGRHAPALRTIVHLSDTHLLAGDRRLGGAYDSTGGAIAALAAVERTGIRPDAIVV
TGDLTDLGEPEAYQRLREIAEPVADRLGAPLIWVAGNHDERPAMREGLFDEPGSLAPLTS
VHDLDGLRVVVLDSTVPGWHHGDIDAAQREWLRQVLAQPAPLGTIVALHHPPLPSHIPFF
DILELRDQDALAEVLAGSDVRGILAGHLHYSTSGTFAGIPVSVASATCYTMNLQRPPTEV
NGMDAGQSFHLVHVYDDTITHTVVPVVEAPTGDYFSAEWVERMSRLSPDERLEAFSRKPD
>A0A1S8P6J1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium beijerinckii|TrEMBL
MSEKIKYIKCADDLASIRSINTLLVTSQYYITGLYSHIIKIWDKNVFKSDDKNKKPEKIL
RGHNGEINSIIMISEDEIASASSDGTIKLWNIENGANLFTLRGHSAPVMCLTKLENNIIA
SGADDGVIKLWNIEECSEVLSLEAHQNDIKFIEKFENEILVSASKEGEVKLWHIENYECT
FIDELQFNSISSVIKLGEKHLAIFERYSKTIYLNIESREKKVVYCTEEVINSVEKIDETK
VIVYFYNNKLMLYDFIENKKSIIDIKKFKLYNIKYLENNEIILLGYTSNSILNLETSESY
NLYDNNNDIECIEKIDEFKLVYAESSGSIRILDVENEKETFLLDRDKDRTTSFAIIDENT
IVSASYGGYLKVWDINKCEVIMKIKAHHRKINSVIKLDEKRIASSSNDGTIKIWDFGSGK
ELSCLFGHSNNVTKIIKISENIIASASHDRTIRIWDLKEEKETAVFSAHLLKIVSLIRLD
ENKIASTSHDGSIKIWDIKNKKVITTINCSNKIKATSYLESEMTLVVGFENGNIETYNLK
NMPIVSTSYVENISSQIREIKVLANKKIIFTNSAGDFGIIRRNINLTKSNELILKIPVKT
LLLGNSGAGKTTLGYWFDKGEFNEEIRSTDGMQFFCVKADSKIEINNNTKADVEYNIWDF
GGQPEYQLSHQQNYKGAKIIFLVVDLHLPQSNDISNNFWIDRIIEHYRNKDISSSVKIIV
VGTKVEKNQINNDRLESIKLKIKDNIPEIDVHCEIVNVKELKRENFEVKDKLKAYIREDF
AEYNFQSFKLDSSKIMEEILNLANKEGYIQEGKIKSRLSNELKDEIDIVDRSLASEINFL
EETGKIEILSNTELPCIANEILKENFEEDNFDGMEKMSSEKIILLRPYWKNIVAKSILVT
AQNNKNIIASIKEEDLYGLNCKVEFDKFEMDSKKTSDTELFKKARNDKTFMKIFMKNIIN
NFVTYNIMYRKLGMFVFPSRFNSKNLFIPDSSFYRELSNFKIVLRANIEESLAVIVTNIF
HSGEFKILTHHFNGIKLADSEGSSYLLLFDRKDINLESKVQYSVNILIHAEYKARKEKEL
VALINIIANKHLIPQYKHMEFQIKEKNNLLGKIVFDLNQDVLNKVYSEVKNCIEALSCEA
CKPLSNTGDGMLVKSQNTYEIIETEYIDALERDKVKKIIDKINNEIEIEKEVINNRLDLY
YNRISELKNDKKEKDTNINILHISDLHFTKDTNEENEANLLLKDLESVYFDDSSVKLKKN
NIDYIVLSGDMSNASSPEEYRKVCDFLSKLCYQCNLSAEQIVMVPGNHDYSREITYKSYE
VKYDKKLDKENDFFINDKLYLKKIENEWKKKFHNFSEYLYEYVYNHEYDVNTENQLKIIK
SELQPDFKIAFFMINTASDIDHFFPLRTCFDTTNLINNSINISESEYIKIGVGHHPLNFE
NNVDFINALQNEGFKMYLHGHVHRDMTISYSNPQIKNNEMVIIGAGTFCADKHHMWQGVP
QRYNIIKIAMSNDNGEVNIKVNTRQRESSNFYWQPANIYYDKKEDKMTNVWEL
>A0A379A4J1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nocardia brasiliensis|TrEMBL
MHISRVAEHPRPDHVLFHFSDTHLIAGDGDLYGDVDADVRLRQLLEQAAASRIRPTAIVF
TGDLTDRGEPGAYDKLKALVEPFARSLPAPIVWVTGNHDDRGTLRRKLLGERPSTAPLDR
VHLIDGLRIIALDTSVPGHHYGEITDDQLAWLRSVLAEPAPFGTILAMHHPPVPCVLDLA
VTVELRDQRRLADVLDGSDVRAILAGHLHFSTSATFAGIPVSVASATCYSQDLGVEQGGL
RGRDGAQAFNYVHIYPDTVVHSVVPIDRGPTVGSPSSADEAGARLAAQGIVIPPAARIPH
VMRRRATTPESDDETVR
>A0A3B0ZV75|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MGSTLNVVQMTDLHLYADTGGTLQGMNTEKSFCTVLEKIQQGNTNPIDFIVLTGDLVQDE
SEQGYQRLKQHLCQTGIPFYLVSGNHDAPDLLTKYFSDGAYGAKRSVRRNGWQFIFVDTH
EKGSIGGRVSIDVFDELAHLLKQHETEPTALFMHHPPVPIGSAWLDRIALNNAEKFHSFV
SEHANLQLVVCGHVHQESEFKKEGVTYLTTPSTCFQFEPQKEEFSLDHRLPGWRVFKFCD
DGVFSSRVERLEKSLQTK
>A0A4P2QMZ9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sorangium cellulosum|TrEMBL
MELRVIGCHGGETPRHRTCAFVVDDVLAIDAGSLTSGLEVKEQAKIEACLVSHAHLDHIR
DLATIADNRCQLGCPPLVIAGTRETLRTLKKHFFNNVLWPDFAAIPTAAQPTIEYLELKP
ERPTMVAGRLVRAVHVTHTIDASAFVIEGSGGAIAYSGDTGPTERLWEVLNQQQDLRALL
MEVSFPDREQRLATVSGHHTPQTLAVELQKFRAPKDLPTMLYHIKPVFQAEVERECAALK
GLNLEVLQLMDHFVL
>A0A160THC0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MLNLVKTLVLFCALGLSTQALAAEKFWTVLPLGTSGGLAEGNMSCYLIAPKGSDKFIALD
GGTVREGFYAAKKSGAFNKLALTDKKAALENPLSLIHAYLISHAHLDHIAGMIINSPEDT
KKPILAQTNVINDLKDYIFNWRIFANFADQGTAPLLNKYEYWDMSHGRELPIPDTKMSVR
IFPLSHVEHGASTAFLIHSDNHYALYLGDTGDDKPENSELLKQLWIEVAPLIKSKKLDGI
FIESSYLNGRPDKLLFGHMTPSWLLHSLHELATITNPKDPKQSLKDLTIVVTHIKPEASL
DGMKIVKEMKSQINALNDLGVKFVIPEQGNILEF
>A0A1B1KB82|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodococcus opacus|TrEMBL
MSGTEAADIRTAEYPRPSHFVLHLSDTHLVDDDLLYGAVDSEATLRQIFTEIESSHARPD
ALVFTGDLTDRGQPGAYEKLRAIVEPVAASLGAQVIWAMGNHDDRGHFRTELLGQEPSYE
PIDHVYDVDGLRIVTLDTTVPGHHHGEISESQLIWLAQQLAVPAPHGTILALHHPPVPCV
LDLAVLVELRDQPRLADVLRGSDVRSILAGHLHYSTTATFAGIPVSVASATCYTQDLNVP
AGALRGRDGGQGYNLVHVYPETIVHSVVPMGSYDTVGEYVTADETEQRLAAEGVRIPDAG
EQAVTRVAV
>A0A0A2CSE6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Prochlorococcus sp. MIT 0701|TrEMBL
MQLSDPHLVAFNHRLVRGQNPLLNLQFALQQGASHSPDLLLITGDLCHDESWCGYVLLRH
ELQNLAPSIKVAVLPGNHDNPLFIKAALGRHAFTAPADLNVDGVRLILLSSHVSGRTAGQ
LGESQLQWLDSRLSDIEQFGRPLVVALHHPPLPIGSSWLDAIGLVEGEALIKLLTPVQEL
RAVVFGHIHQHWQGVLPGRTDVLVLGCPSTLCSFKAVQPCFLGREDEPGGRLIELDESGN
LFEKLLRWSYPDLDQGDVGR
>A0A161XJW9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudovibrio sp. WM33|TrEMBL
MIFAQLTDIHIKADGKFAYNCVDTLSHLRQAVAHLNAFRPRLDFVVISGDLVDLGNADEY
ELFRQEIDQLDMPFYVIPGNHDHRDAMRDAFADHDYLTSEGALQFSIEKDGLRIIGLDTT
IPGKHDGHFDADKQAWLRDELEAHKEQPTLVFMHHPPFKTGIQHMDDIMLMRADEDFWPV
VTGQSQIRQIACGHVHRAIEVFKNGIPVSICPASGHQVTLDLDPDGEPGFVMDPPAVRVF
RWSEGELINHLSFIGGFGGQHPFFDKDGKLID
>B9WHF2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841)|TrEMBL
MSFEITILGSSGGPLEGSTCSILLKPANISYHDIINDNLPDQLLCIDAGSGMGKLTEIIH
QETTTKTSYCNFLQYYPDCETVSYYYHPDIAITTPFSNFQPGRPILHTQKVFNNLQNYLI
SHSHLDHVCSVVINSAGFNKNVSNKTLYGSHYTINSMQKHLFNGKIWPNMPSFKIVNLNY
LESNRSERIGIYTVRMFDLSHGEFNKLTEEKEEAQHHINSNSNNIWKKRYDRRRSSITTI
PENTSGLIIKNSEALNHHYLSSAFLITLDVPESTITKENPPSILIFGDFESDLTSKLSRN
LFIWKNIAPLILRNQMKAIVLECSNCIEIDANELYGHLTPKLLIYELKQLAHECKQLDTT
TNIEQPLLGLNIIVNHVKEPITDPNEESQLHDPRKRILTELNKLNAVEKLGCNISIALSG
TSIMV
>A0A0H2M312|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Variovorax paradoxus|TrEMBL
MTTTTTEDTTFLVQLTDLHIREPGRLAYGRIDTAPFLEHAVQSVLRLPQRPDAVVITGDL
SDFGRAAEYEHLARLLAPLTMPVYLMPGNHDDRGQLRRSFPGHAYLAAGVGSAGFVQYAV
RVGALRLLTLDTCVPGASHGELCGERLGWLEEQLDACRGEPVVIAMHHPPFRTLIGHMDE
IGLQRGAEALEALVARHGNVERVICGHLHRAIDVRFGGTIASTSPAPAHQVCLDLSPGAP
SAWALEPPGFRVHAWSAQDGRLVTHLAASGTFEGPFPFHDNGELID
>A0A151ANB9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium colicanis DSM 13634|TrEMBL
MRVMKIGLYAISDLHLSLSSDKPMDVFGEQWNNHHERIRENWIKKINDKDTVLIAGDVSW
SMKMEDGLADLEWIHNLPGRKIISKGNHDYWWGSISKLNNLYEDISFIQNNFFSYEDYAI
CGTRGWTIPGDKSSSHDIKIYNREQIRLKLSLDKAVSSGYSKIIVMIHYPPVNDKFEASN
FTEIFEEYGVEKVIYGHLHGPSLNRVFEGTYNGVEYIMTSCDYINFDPIKVI
>A0A7H4PHQ7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella michiganensis|TrEMBL
MYSTLQESGISPAKRVLLGDHWQVLLMDSQVFGVPHGELSDFQLEWLEQKLTEVPQRYTL
LLLHHHPMPSGCSWLDQHSLRNAGALDCALAAFPRVKHLLCGHIHQELDLDWNGRRMMAT
PSTCVQFKPHCANFTLDTVSPGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEGY
>A0A161Y378|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium magnum DSM 2767|TrEMBL
MRKFKITALILIIMTLIISITVYIKGVVSKTSDSKQVQSSVNIKTPEDDGLTFTVLGDVH
GNTAKLDNAIKDLHNINEKMDAMILNGDNVDEGLKSQYDIVKNTLDKDKELLPEIIIKNI
GNHDFFDYKKGKNNDKDVQNFIDMYLDFSGERSVYHDRWIKGYHFISLGSESGNTKELGA
VNAFLSEQQLVWLKEKLAENHEKDKPIFVFLHQHLSTSIKGWAGVEQRKELSEILSVYPE
VILFTSHTHVLLSVDNVKMNQPFTTVHTGAISYGILPEGYTIKRLYEDSEGLYVEVHGKN
IVIKGRDFIKKSWIFSKNISK
>A0A162RU49|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium magnum DSM 2767|TrEMBL
MNLKPFKPIIDLLSFAYCNILFKITYRNNSPLPKYPLKFDTSRNFKIVQFADIQDGPNTD
PRTLELMNRILDKEKPNLVVLTGDNIDGKCKTAEDVKKAITNISKPMESRNIPWAVVFGN
HDDEHFMMSKEQMMNFYMTFNYNVSQIGFKTENRVGNYNLLIHGSSSQAPKFNVYFIDSG
KYSILGVYDYITKPQICWYKTIANNLKKQYKKTIPAIMFFHIPLQEFYTAYKTGYIDGLR
LESESTSSINTGLFDAIVNTGDVKGIFVGHDHSNTYTAALNNITLGYAGNVGYATYGNPK
LQKGARIFEINEANPSTINTRMIFSGDVGLN
>A0A011PRF2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Accumulibacter sp. SK-12|TrEMBL
MRIVQLSDLHLSSQPLYGVVDTLSALDRALQRLTAGPEPDLLLLSGDLTSAGRSEEYALL
RSRIAALPFPSALLPGNHDDRDNLRAAFCAQAWTPPPLCCQRIDLDGGTMLLLDCIVPGE
EWGEVAAPQIDWLESACPRRRPVLLALHHPPFSVGIEGMDRIRCRGEASLAAWLARHEEV
EALLCGHVHRFVSTTFAGRPAIVAPSPAHQIALQDGPLAYTLEPGACLLHDWSPGQRLCS
HYLPVAVSPTQCYSDG
>A0A670IEK0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Podarcis muralis|TrEMBL
SVPLEVQDWLTVTFARKKEAYSIKPEDQPSIRTISYAVQASVLVKRMFRTPTSASGLAYP
EKVIAAFKDIDKWDFDVFALNETCEGHSLKYLMCDLFNKYDLLRQFKIPITCLISFASAL
EVGYSKHQNPYHNVMHATDVTQTVHCIMLHTGMMHWFTDLEILAILFSTSIHDYEHTGTT
NHFHVRTRSEMALLYNDKSVLENHHVSAVYQLMQNEDMNILVNLTNEEWRELRRLVIEMV
LATDMSNHFQQMKYLKHVLKYKLMSMIVHAADISHPSKPWKLHQQWANALMDEFFKQGDK
EAELGLPISPLCDRGTTNIAETQIGFIDVIVKPIFSLIIEAAEKIVEPLIYEAFETGCSS
SRDSGYFSGGVGASQVRRGGAKAPGQGRSSVSRPQPLPSLPGRRVFASPEL
>A0A2N7RRC1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Janthinobacterium sp. AD80|TrEMBL
MRTIVHLSDLHFGKVDAALLAPLRVLVERLEPDVVVVSGDLTQRARSVQFQQARAFLDSL
PGPQIVVPGNHDVPLYNVFSRFLTPLVKYRRYLTDDLSPEYVDEEIAVLGINTARSLTFK
DGRISHEQIDFLRERLGRLPPGLTRIIVTHHPFDLPENFDKDDLVDRAPQALQMFSECGV
DLLLAGHLHASVAGNTAERYKIAGYAALMVQAGTATSTRGRGESNSFNVLKVEPSCIRVE
RYSWSEEKADFEKVSTEAFERQGGVWASLRPL
>A0A2N7REZ3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Janthinobacterium sp. AD80|TrEMBL
MRLLILSDLHHELWRDDAPQGDLAISRPDAVILAGDIDTGTRAVAWAATAFAGLPVLYVH
GNHEGYGHHLDKVRHELRAACAATPNVHFLDANTHLIADQDGNKVRFLGATLWTDFRLLG
DDTRQTAMRDAEALMNDYKRIRLAGMGFRKLRAADTAMFHAQQKAWLARELAQPFDGGTV
VISHMAPSLQSLDAAHGGAAHAPAYASRLEELAAQADLWVHGHIHASRDYQLGPCRVVSN
PCGYKTRDGTPQNPDFDPDFIVELQPRRSGANRPA
>A0A1C6ILN8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Clostridium sp|TrEMBL
MKFLHLSDIHFLREYPKAEKGYNAIFNDMTSPLIQLKKALIMVDLSKIDFVIITGDLVES
GMYEDYFSLKCELEKLLGNVPYILTLGNHDNKAAFYKGWFNKECNEPYNTVNEIDNLRII
SFDNSVYKNSDGFISNEQYKWLENQLKDGSKKDTILILHHHLIKDQFTTPSVDIDDNFEK
IIRESSLVGIFVGHTHHPFNGSFADKPYFSTGSLSFIGHDEGNGIVRFEENAQFSICTYE
DGKISVEVISASNDNKLLGIVNFKE
>A0A0G4JR48|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Brenneria goodwinii|TrEMBL
MLLAQISDLHFHRDGRKLYEFVDVNSRNAEVINKLNTLAERPDAVVISGDIVDGGREQEY
QVARNVLQMLNYPMYIIPGNHDDKQKFLQAMRPLCPLLGDDAENMRYAVDDFPVRLLFID
TSLIGESKGWLTPATIAWLEQQLIDHPARETAVFMHHPPLPLGSAQMDPIACENGQELLR
LIDRHPQLTRVFCGHNHRLIVTQYRQAIIATVPGTVHQVPYSYIDGTPYYNLEPAAVVMH
RYVPVTGLVSYCQSLAPFAGPYLYDISASSPVDKSCL
>A0A1Q2HX59|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Corynebacterium glaucum|TrEMBL
MTRICHFTDTHLLADRGLHYDRVDTSALFEAAIEVAAQQERCDAIVLSGDISEDGSSQSY
QFAKSLVDSLAERWKAAPVYACGNHDNRDSLREALGVGDPLAAHSVVELPDLRVLSADTS
VPRAGYGELGFEIEWISRHIPESKPWVLVLHHPPAEAPTVLHDALRLSDTDKLSETLRLH
ENLPTAILSGHYHLPAQHTLGSIPVLVGPAIANETVVGSPLSEKAREISEFQIVEIGKSV
EVTRVQVGGSGETIFQYEPELVRTIAAGAGRPGWTYPGKFAAHLSRSAGD
>A0A518JT39|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rosistilla carotiformis|TrEMBL
MPIHKIPQSRRRFLQTTVVGGGAALLMSSTQRLAASEGDPTVIALLSDTHIPNSPDVEAR
GINMTENLQRVIGEVVDRKTRPTDLIINGDCAYLKGLPGDYQNLVSCLAPLDRAGISLHL
TMGNHDDRQPLYDALSDQRPADAQVMAKHVSVIETPHANFFLLDSLFRVNVVTGEIGAAQ
IQWLAKQLDARSDKPAIVMTHHTPQFTEPAEGKPWTGISDTAALMEVLESRKHVKAYLYG
HSHHWSHSQRGHFQMINLPPVAYLFNDSSPNGWVEAVLTPEAMRLELQTLDPKHPRSGET
VMVSFAS
>A0A161UW92|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudovibrio sp. W74|TrEMBL
MIFAQLTDIHIKAGGKFAYNCVDTLSHLRQAVAHLNAFRPRLDFVVISGDLVDLGNADEY
ELFRQEIDQLDMPFYVIPGNHDHRDAMRDAFADHDYLTSEGALQFSIEKDGLRIIGLDTT
IPGKHDGHFDADKQAWLRDELDAHKDQPTLVFMHHPPFKTGIQHMDDIMLMRADEDFWPV
VTGQSQIRQIACGHVHRAIEVFKNGIPVSICPASGHQVTLDLDPDGEPGFVMDPPAVRVF
RWSEGELINHLSFIGDFGGQHPFFDKDGKLID
>A0A484UWY8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|plant metagenome|TrEMBL
MLIAQISDLHIRLPGQKAYRVVETDAYLPPVVDALNRLDPRPDCVVITGDLTDFGRPAEY
AHLSKLLAPLQLPFFLLPGNHDDRQALADAFPEHAYLRTDGPFIQYAVDQHPVRILALDT
VVPFKGHGALCAERLQWLETELAREPGRPTLVAMHHPPFKTGIAHMDAIGLLSGAPELEA
LVRRHPNIERIICGHLHRTIYARFGGTVASCCPGTAHQIALDLRPAGPSAFVMEPPGYQL
HTWQGGALTTHSAVLGEFPGPYPFHEEGALIDE
>A0A7Z0UYL9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moraxella catarrhalis|TrEMBL
MPNITNNRTFNIVQLSDLHLTGDIGQAPSYQRFLAVFQTATHLNPDLWLLTGDLVNDGNS
DAYDWLFNQLKVTKTPYLAVAGNHDVTHEIGIHLAHQERIHVPILPDQRLKNCFRYTFQA
GHDWQILLLNSSVSGEIFGLLTHETLLWLDQTLTTHSEHTIIALHHHPTKVGSDWIDAHL
LKNHQDFWHVIKKHAHVHTILCGHVHQVHTLHPLPAHQVQLLSCPSTDRQFMPFVDNFQI
ADTPAGCRMIQIDNKGIVSSYIQIVQNTHSFCLNNAN
>A0A853KPE6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moraxella catarrhalis|TrEMBL
MPNITNNHTFNIVQLSDLHLTGDIGQAPSYQRFLAVFQTATHLNPDLWLLTGDLVNDGNS
DAYDWLFNQLKATKTPYLAVAGNHDVTHEIGIHLAHQERIHVPILPDQRLKNCFRYTFQA
GHDWQILLLNSSVSGEIFGLLTHETLLWLDQTLTTHSEHTLIALHHHPTKVGSDWIDAHL
LKNHQDFWHVIKKHAHVHTILCGHVHQVHTLHPLPTHQVQLLSCPSTDRQFMPFVDNFQI
ANTPAGCRVIQIDNTDTVSSYIQMVQNTR
>A0A1R4JYB2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Marinilactibacillus psychrotolerans 42ea|TrEMBL
MQSPLVPLEKCLEEIQSKQQIDLLIISGDLTDDGEAEDYRFLKQVIQNIIGDIKVIVTLG
NHDIKNNFREGWLNESPSDKPYNIIETFKEFHIISFDSAIYENSNGYVSESQLKWLDQAL
ESKQDKPVILVTHHHLIEHQSSIPNLPESQLILDKLQNKNILCILNGHTHHAYKTKIENI
PYYTVVGMSFVGEDIGQQQIQFEEKYGYNIYQIKNSQIKDVEHKIVSTGRQLKIVDMNQ
>A0A5P9GVD3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Erythrobacter sp. THAF29|TrEMBL
MGDGKPALLIAQITDIHIGFDADAGEDEFNYKRFIAVRDHLLAQEVQPDCLILSGDLADG
GDPKCYERLARAVEACPFPVYPMTGNHDTRSVLVKAFPGFENEEGFVQYTIDFEGLRVLC
IDSLDQGRHGGAFCEKRAAWVTRELDAYPETPTLIVLHHPPIVAGIDWMDPKPSEDWYQR
FHETVAGHEQIVGIACGHLHRPIVSEVAGIPLSVTPAVAPAVTLDLRPVDTEVADNRGIV
AAEPPFYSLHRWHDGRLVTHMQPVGDWQVLARYEEHLKPMMQGLADERD
>A0A4W4HQC4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Electrophorus electricus|TrEMBL
YTSAVTRQQKELSYPSVNLLDFVSNVDYEQFKKNLEYTASLLEALYRDETRQSLDMEDQL
QELRPDSVPKEVHNWLASTFMQQARRPLRYPDYKPSFRSIVHAVQAGIFPFSQHDLLTLF
TELMIRYELNSRFKVPISCLMSFLCELEQGYNKHNNPYHCQTHAADVTQTLHCLLLRTGL
VHWLTELEVLASLFAAAIHDNEHTGNTNSFHILTRSDLAITYNDRSVQESHHLSSTFCIL
QNEQMNIFTNLSREEWVELRSLVIEMVLATDMSFHILQVKAMKHSLQQQERVDKAKALSF
LLHTADISHPAKPWVLHSRWSKALTDELFRQGDKEGELGLTISPLCDRNTAPVAQSQIGF
IDFIVDPTFSLLMDMAEKIIIPLVTLPVALSDNSNCVSLSAFDDSGAAGNFLDTGLAAQL
GITTLTLEPPLHVNSINRQPIGEGAGKHQTALVTLKVALFHSELIHFMLLPMSSDSIILG
FPWLSTHDSSISWSGAELLSWSKHCLQHCMSLPVLSTTVEGPESPYSQSIPLPI
>A0A3P7IEP2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Strongylus vulgaris|TrEMBL
MGTPIAAQIIMCVRQPMHSSVVPYHNWSHAFSVAHFCWIALRTPAVLHGLDELERLALLI
ACLCHDIDHRGTTNAFQLQSVSGGVVKTPLAQLYSSEGSVLERHHYAQTVQILQMKECNI
LDQLTRTQYQTVLSHIRDVILATDIAVHLGKVGRIKAMVDEGYDPMSRDHHYLFMCLLMT
SSDLSDQSKDFRNSKAIA
>A0A4W4HQE0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Electrophorus electricus|TrEMBL
MDMVLGLCFLTPIVIRPSMLLLHFIPSNLVPLNYIDESNVDYEQFKKNLEYTASLLEALY
RDETRQSLDMEDQLQELRPDSVPKEVHNWLASTFMQQARRPLRYPDYKPSFRSIVHAVQA
GIFVERMFRKMSSTAMTDQPLAVVNCLREVDRWNFDVFALDVGSSGHALKTLFTELMIRY
ELNSRFKVPISCLMSFLCELEQGYNKHNNPYHCQTHAADVTQTLHCLLLRTGLVHWLTEL
EVLASLFAAAIHDNEHTGNTNSFHILTRSDLAITYNDRSVQESHHLSSTFCILQNEQMNI
FTNLSREEWVELRSLVIEMVLATDMSFHILQVKAMKHSLQQQERVDKAKALSFLLHTADI
SHPAKPWVLHSRWSKALTDELFRQGDKEGELGLTISPLCDRNTAPVAQSQIGFIDFIVDP
TFSLLMDMAEKIIIPLVQDNPEPPEPINRHRYTEIVLSLLTGEAGAWGTALWDSQDPVLQ
SETGFYNLFKVVFNHPADENDPGTISCETHSVIDALAIPL
>N1M0J2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodococcus aetherivorans|TrEMBL
MGSPRGAERIAEYPRPSHTLLHITDTHLVGGDELLYGTVDADARVRQILADIRASQVQPD
ALVFTGDLADRGQPDAYSKLRGLVEPVAQALGAQIVWAMGNHDDRATFRELLLDQAPSTG
PIDRVYDVNGLRIITLDTSVPGFHHGEISQEQLNWLAQELETSARFGTILAMHHPPVPSV
FDQAVLVELRDQAGLAEVLRGTDVRTILAGHLHYTTTATFADIPVSVASSTCYTQDLNVP
AGCQRGHDGAQGFNLVHVYPDTIVHSVVPTGSYITTGRPSTAEDAAQRLAEAGIRIPENP
DVTVRV
>A0A1N6Z1Z0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mucilaginibacter lappiensis|TrEMBL
MRIKQTLLIITYILLPFITLAQPKNKTAFRMVPLGVLGGIDESNLSAYMLAAAGTDQYIC
LDAGTLHDGIQKAIANKAFRVSGERVLRQYIKGYFISHAHLDHIAGLIINSPEDSSKNIY
GFQSTIETVKTHYFTWASWANFADQGETPALKKYRYKVLDPGTETDVENTSLKVQAFPLS
HSNLTSTAFLVQSNEDYVLYLGDTGPDAIEKSTNLQNLWQAIAPLIKTKKLKAILIEVSF
PNEQPDKTLFGHLTPHWFMTEMDKLARLVSPAELKGLNIVVTHLKPPVSSITRIKAQLKA
ANQLQLNLIYPVQGKALNF
>A0A0D6FFC3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Alcaligenes xylosoxydans xylosoxydans|TrEMBL
MLIAQITDLHMRTPGDKAYGIIDPAAFLGPAVRALNALTPRPDCVLITGDLTDLGRPHEY
QALREQLQALEIPYFLLPGNHDDRAQLRAAFPDHGYLQGQGPFIQYAVETYPLRLLALDT
VVPMKSHGELCDERLGWLAARLAEQPDRPTLVLMHHPPFQTGIEHMDDIGLLAGGPELES
IVARYPRVERVLCGHLHRTIFRRFGGTIASTCPGTAHQLALELGPRPTLQYIMEPPGYQL
HWWHDGALVTHHAVIGEYPGPYPFA
>A0A484R6V9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|plant metagenome|TrEMBL
MLIAQISDLHIRLPGQKAYRVVETDAYLPPVVDALNRLDPRPDCVVITGDLTDFGRPAEY
AHLRKLLAPLQLPFFLLPGNHDDRQALAEAFPEHAYLRTDGPFIQYAVNQYPVRILALDT
VVPFKGHGALCAERLQWLETELAREPGRPTLIAMHHPPFKTGIAHMDAIGLLSGAPELEA
LVRRHPNIERIICGHLHRTIYARFGGTVASCCPGTAHQIALDLRPAGPSAFVMEPPGYQL
HTWQGGALTTHSAVLGEFPGPYPFHEEGALIDE
>A0A162GHF7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rathayibacter tanaceti|TrEMBL
MDGTAGAGGAEVDGTRRPQLGHFRAAERVVAHLSDTHLLADGAPLYETVDTSARLAQAVE
RLIEHGGRLDAIVVTGDVADRGEEDAYLRVRAQLDPLGERFGCPIVWVMGNHDERRAFRR
VLLDPSGADAASPGGRRAVDVSGAESAPVDQVVDLGGLRLIALDSAVPGFHHGALADAQL
KWLADELATPAPLGTLLALHHPPLPTPLGAMTVLELRGMDRFEEVVRGTDVRAILGGHLH
YPTAAMFAGVPVFVAGAISYTMDLGAPEHELSGIDGAQSVSLVHVHPETVATSFVPTRRA
PIATRFGSDLLESLEALDEQGRIDLWSRMPEDS
>A0A263K1W6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFID
SSHAGTSKGWLTDETIGWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGDQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A183UG45|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxocara canis|TrEMBL
MAAELLVQGSTLSIAPEDILRFTVRDIPASTSFHPDFTQFFFVPRSIGTGDTYIEASLSM
FKELGFIERFRLRRRTLARFLLMVQKGYRDVPYHNWSHAFAVGHFCYLLVRTAAVRSALT
ELERLSLFVACLCHDIDHRGTTNAFQLQSKTPLAQLYSSEGSVLERHHFAQTVSILSMEE
CNIFDQLTRQQYQTVLDNIREIILATDIAAHLRKVDRIKKMVEDGYDRTSSEHHYLLICL
LMTAADLSDQSKDFKNSKAIAENIYKEFFSQGDLEKQMGNRPLEMMDRDRACVPKIQLEF
MDTVALPVFDYVSRILPDVKGTYNAILLNRRCWQVLDQILKEEGLPRGGLDYLRNVDLEE
KVMKRIADSDEQVPPYAHVSFIFALLFLLYIHM
>A0A853SVB2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Janthinobacterium sp. HH102|TrEMBL
MRLLILSDLHLEVWGEDTPAIDLAASRPDVVILAGDIDTGSNAIAWAARTFGALPVLYVH
GNHEGYGHQLERMQDAVRDACTSANAQGANIRLLDGDAVTLDGVRFLGVTLWTDFLLFGA
ERRDEALSAAQSYMPDYKRISTGGDTPRLLCASDTAQLHAQHRSWLEQQLAQPFEGKTVV
ITHMAPSMLSVEEQYATNLGSPAFASQLDELVTQADLWVHGHMHASLDYRVQGCRVVCNP
CGYKRPDGTPENDRYDSGFIVDLAGTV
>A0A1Q2S6B3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Helicobacter pylori|TrEMBL
MQVYHLSHIDLDGYACQLVSKQFFKNIQCYNANYGREVSARIYEILNAITQSKESEFLIL
ISDLNLNLNEAQYLQDKIQEHRLQNKNIQIQLLDHHISGKEVAESFHWYFLDTNRCATKI
VYKFLKKHYAILEPKNTTWLEPLVEMVNSVDIWDTQGYGFELGKVCMRMITQSSELNRFM
FDDENRDYKLKLLEEVKNYLFLENAPVAYDNDLFKLKKIALGGDPDTETMDNISSNTQTH
LLSLKKHDCSVYYQDKKGFLSYSMGGISVLANLFLTQNPDFDFYMDVNSKGNVSLRANGN
CDVCELSQMCFNGGGHRNASGGKIDGFRESFNYRDIKEQIEEIFNNA
>A8JBS1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chlamydomonas reinhardtii|TrEMBL
LGDADSWAFDTWRLAEATQGHALSALAFYLMYREGLIAKFKIKPAVLARLLRALEAGYPA
NPYHNATHAADVLQTLHVILHGAQLHVHYLDKLGLLAAYFAAIVHDHNHPGLTNDFLIST
HDLLAIRYNDKSPLENHHAASCFGLMALQPELDALSTLSKTERGTFRKQVIEMVIGTDMK
QHFAILAHFNTVHRLASYSLLKANCLQTYVDRLEGAARTVALKVADIGHLGEDLEVHKRW
LGVLEEEFFNQGDRERALGIPISPLFDRNKQGVSKSQARVLQYTVAEFELGACDVP
>A0A841EIC0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Arcicella rosea|TrEMBL
MYYRLLICFLLFSAKLFAQQKQPAAFQVVPLGVKGGTDEKNLSAYLLAPVSTNDYVCLDA
GTVYAGIEKAVNNKVFKVSASEVLRKYIKGYFISHAHLDHVSGLIINSPGDSSKTVYATQ
KCMEMMQNHYFNDETWANFGDEGKGFPLKKYHFQTLKTGEESAITNTSMTVKALPLSHVN
PYQSTAFLIKNQNNYALYLGDTGPDEVERSDKLALLWKEIAPLIQQKQLKGIFIEVSFPN
EQPDKFLFGHLTPNWLMKEMNKLSELTGKEALTGFNVIITHLKPPAVNEVKIKKQLTEQN
TLGLNLIFPEQGKRFEL
>A0A853SF85|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Janthinobacterium lividum|TrEMBL
MRLLILSDLHHELWRDEAPQGDLALSCPDVVILAGDIDTGARAVAWAASTFAGLPVLYVH
GNHEGYGHHLDKVRQELRALCAATDNVHFLDADTHVITDKAGNAVRFLGATLWTDFRLLG
DDTRQSAMRDAEAVMNDYKRIRLASMGFRKLRAADTAMFHAQQKAWLARELAQPFHGATV
VISHMAPSLLSVDDAYGNEGCSPAYASRLDELAAQADLWVHGHIHASRDYRIGQCRVVSN
PCGYKTRSGTPQNPQFNPNFIVELGTP
>A0A5E4R7L0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Leptidea sinapis|TrEMBL
MYVDLLVEYFEAKRSDCATSERLPLGNGTKQGGLTIVRRSSSRGKTESSPPTDEQLDQLD
LETEHLPAVDTPDACDKAALRGEIAVETLQNNLQYAAKVLEAVYIDETKITRHAEQPRVQ
PTTLHMRRLRTPCWARCSVEKPNEAKRLADEDDELSEVQPDAVPPEVREWLASTFTRQLA
TAKRKSDEKPKFRSVAHAIRAGIFVDRIYRRTLDEWSFDVFALHEASLGSPIKYLGYDLL
NRYGMIHKFKNWLSDLEIFATLVAAIVHDFEHTGTTNNFHVMSGSDTALLYNDRAVLENH
HISAAFRLLRDEENNILQNLSRDEFREFRTLVIDMVLATDMSFHFQQLKNMRSLLTLAEP
SVDKSKAVSLVLHCCDISHPAK
>A0A140L8M4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Fervidicola ferrireducens|TrEMBL
MRFLFFTDTHIRGTGPQSRTDNFYETLREKIRELINIAHEENVDVVLHGGDIFDRPDVSP
SLVRDFVVLMKDLKPPLYAIAGNHDIYGQNPSTISRTMLGILDSAGIIKLINPGEKIFFN
DRGIKIQLTGQHFFYGIDSENQRLAYCIKKDEGVDFAIHLVHGMLLDKPFIPGVSHTLIE
DILATEADVTLSGHYHAGFGIINIENKYFINPGSIARIDGTLSELMRIPAVILLNVTKDG
IEVQKRILKCARPGHEVFDQKKLEENSFREQKLAEFVQVINSTGEYNFTNITAIVEQLAK
KQNMDARIVKEALCRIGKAQEMLSQKDGSDIYEVS
>A0A486TMI0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANAEVVSQLNALRERPDAVVVSGDIVNCGRPAEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDAQNMRYAVDDFATRLLFID
SSRAGTSKGWLTDETIGWLEAQLFEGGDKPATVFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>D4E9K7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serratia odorifera DSM 4582|TrEMBL
MLKKVLAVCLSGYSALAMAGFDVVALGVNGGISDGNLTSYLIRSDGQTQYVALDAGSLLP
GIAKGLEKGSFPQVTPQLAAPYTPQGYVFRQLIGGYFISHAHLDHLAGLVLAAPEDNKKT
LYASSDTVLTLRNHYFNWKVWPNFTDSGNGARLGTYRLQPVREQQRFTFGTTGLSGVLYP
LSHDRYPSSMVLLSDRSGAFAYFGDTGPDAVEQSRHLDTVWRALGPLIQQKKLKGMIIET
SYPNGVADNQLYGHLTPDWLLKELHNLQKYSGGDGSLQDLPVVISHVKPSIRQGDDVRTT
IKRQLDQGNDLGVKFIMMEQGDRQTF
>A0A6N2T9P0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Anaerotruncus sp|TrEMBL
MLMPFAHISDTHLDCPGSSDFIKRLHREVRDPLENLTCCLQELAARKVAFVLHTGDMVHE
GDAGDYAILRRLFDKYLPGVPVIAAMGNHDHRAAFREGFLGIPSPGDEDFTQEVVLDGLR
ILVLDSAKSGLIGSVSDAQVDWLEERLASPAPRGTFLMMHHPTVCEHPAMALEVSPEFSS
LVENSDIHAIFTGHTHSNYNGFFAGKPLYTADSLAFGMLYIQSEVIYTSRSSYNLCWLDE
QGRVTTHNQLLYPEVQVLQRKSVAQMIQGLPR
>A0A090E9K0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mesorhizobium plurifarium|TrEMBL
MKIIQVTDVHLGRRREIRYGANLNERLDRCIDHINQRHSDATLCIFTGDLTDDGEAESYA
DLKAALSRLTVPFRLLPGNHDRRANLVAAFPENGTDGNGFVQSVFDAPEGEGRLVFLDSL
AEGRVTGELCDKRLGWLDARLGEVAGKAAYIFLHHPPVELGLTLLDPLGLEQPQRLIDVL
TRHGNVRYIFFGHVHRDIAGTVAGIPFSVQRGLHARFMLDLIGDEMVEQAPPAYSIILID
GARVVIHSHDFLEQWPLWSPATGQRVR
>A0A1N6M8D5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio spartinae|TrEMBL
MDKIVQISDIHFCMKDKSHSSRDNLSLVLNKINGLYHEYILVLSGDLVMKADSAHYMALY
QYIRAFTRNEIYAIPGNHDDIALMKKLAIQEEFFKIQDLLEIGINDIVFLDSSEKGEHLG
GGKIDLAYFEAIKSKLRENSNKIIFIHHPPFKIGAEWFKKICLDNGDLLMKSLSEINNLK
YLAYGHCHNYFIEERENTVFLSCPSSWVQFDHTEHHETKYDQQKEIGFNVFHLSDDISHE
TVTISVC
>S9QXP6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rubellimicrobium thermophilum DSM 16684|TrEMBL
MRRILHLSDLHFGRTRPELLEPLLDLARRLAPDLVAVSGDLTQRARRGQFVEAARFLARI
EAPWLAVPGNHDISLDNLLVRLLDPWGRYRSLIQDDLSPRWQDEELTVIGLNTVNRYAHQ
SGRIGRRQLRVIAQAAQERPQRTLVVVMHHPPEHPADSTKPPMRHAGRGVAALVRAGADI
VLSGHLHNARVTPLSAAPGILLVQAGTGLSTRLRSEPNTVNLLEIEPGHVRVHRWAAFDR
PAYEVIESARFLRDLDRPGSPWEMAAHEPCVRPGPAAGPDQST
>A0A2L0H2L4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhizobium fredii|TrEMBL
MTKFIIFTDLHMVPDGTTIIGIDPYRRLANGIDHVNRYHADADRVIFAGDLTHQADRASY
ERLKDLLFELIPPAAVMLGNHDRREVFLEVFREAARDENGFVQQVIDFPDCRAVLLDTLF
APPYDYPMSHAGQLCERRLNWLDRQLGSADDRPVLIFMHHPPHASGFAGIDMIRLINEEQ
FYGLVKRHGNVRHIFAGHVHRTISGSSRGIPFSIFKSPVHQQPMPFDIADASLSVDEPAA
YGIAVVTADGVLVHTEDYEIAKRDAAVA
>A0A095WYL7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudohaliea rubra DSM 19751|TrEMBL
MQLVQVTDTHLAAAAGGTLLGMDTDRSLLSVLEALGRVHPAPDALLATGDLADAGAPGAY
ERLQSYLDAATPRHFWLPGNHDDRATMVAVAGEARLPRELRLGVWQVLMLDSQIPGQVGG
RLGDEELARLEAGLEAAAGAGLFTLVCLHHQPVPVGCAWLDEQRVADADRLFAVLERFPG
ARGLLWGHVHQALERDRNGLKLLCTPSTCVQFKPGQSDFAVDDEAPGFRWLALSPDGGID
SGVTRVPVDLPVDLESRGYQ
>A0A1V4W0L6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pelotomaculum sp. PtaB.Bin013|TrEMBL
MTSNPAICNEELCTLGYNYAMITWATPKRPADTTICFGENPERLTKHTVNQNTEYHWVEI
YGLIPSTRYWYRVESNEVKGSLNSFTTLPKPEGKHLFNYAIFSDTHIASTNPVKDINETY
FGKLVEHSKTLLTQCIMDSKRRNIDLAVITGDLTDTANQKQYLELRDQILPCFGNTPYLL
CIGNHDKFTKNSGIGEKGFLDYVSNREKTCANFVFRDYQFILLDSCRQNDNWGYIYPTHL
QWTKNILQSEGKPSYLFFHHPCNGPDLWFGVKNHKDFLKTIRPFSCVQGVFSGHIHRNKV
TVNHIATGNLPYVEIPATVQFPCAYAIVQVFESGFIYNSYKVSRLDLSEMSRGRFILKHR
GNAILTWYGFGGIGDRCFSYSNNQLFRPARYELAVTLDQQRAIKFYQRVQSFDGASLTCS
NNINNLKVVLGHHDSHSLAFRSYYDKFSHFNINAMISKEGNYDLPQNIKLLIE
>A0A1Y5Q2X9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Sphingopyxis sp|TrEMBL
MLIAQITDIHIGFDPGNPAEYNRERLDRVLGMLIDGPNRPDLLLATGDITDRGDGESYRR
LADIFARCPFPVWPSVGNHDLRDNFHAHFPGFDDGNGFVQYTVELPELRLVTVDTLEEGR
HGGAFCDRRAAWLDAELAKDRVKPTYIVMHHPPVESGIEWMNTHPDEPWVETFSSVVRRH
PQVRGLICGHLHRSVTVAWEGRTIAICSSTAPQVSLDLRPIDADRPDERPMIVAEDPAYA
LHRWNGRELVSFYDNAGVRATLARYDEELQPLVRALKAERPG
>A0A4W6DMM5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lates calcarifer|TrEMBL
MLWLCGVNRTAAVWVQSMKSQMDRGVVDLQELRRNLELAAAMLDAVYTDETRRLLDTEDE
LSDLQAESVPSEVRDWLACTFSRKMGVAKRRPEEKPRFRSIVHAVQAGIFVERMYRRTSN
MAGLTYPPTALTALKEVDQWSFDVFSFHEATGDHALKFLVYDLLTRYDLINRFRIPVQAL
VQFVEALENGYSKHRNPYHNLIHAADVTQTAHFLMLHTGLMHWLSELEILAMVFAAAIHD
FEHTGTTNNFHIHTRSEVAILYNDRSVLENHHVSAAYRLMAEEDMNILVNLNKDDWRELR
SLVIEMVMSTDMSCHFQQIKTMRNALTQTHGIDKVKVLSLMLHAADISHPAKAWPLHYRW
THSLMEEFFRQVLCCSGIHEAFKMIGPVKKP
>A0A086JL60|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii FOU|TrEMBL
MFDRRKHADFPKGQEGFLRFIIIPLYEEIAAVDTTDVVQTCCLQNAVANSERWRQLQSSP
EEFEAIDAKHQAIICVLKDRLEWRVQKNIAPTQRLLRASCAENQVRGSGVFFPTPECSGG
SGAPRASAPAEKRRESASASRDRDPGAADWKEETGNTAQALRERPPTEVAPQVDGEETCV
SDGVHERNRQDEGGGNEEGRRKAAGGETEKQGDDRKDLLHFESRLTH
>A0A1J5RVX0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|mine drainage metagenome|TrEMBL
MKLHILSDLHLAQGALAVPRNDAEAVILAGDIARPAAAVAWASGLDKPVLYVPGNHEFYG
GSIVGTVDELKRLCAGSQVRVLDQDQVIFKGVRFLGATLWTDFMLFGAGEQRTAAMRQAS
AFMRDFSRISAAGAQFTPEDAAALFERQAGWLAGMLSQPHAGPTVVITHHAPSRMSIHPR
FAGSLINACFVSAAEHLLDGDRARLWVHGHTHDSFDYALNGTRVVCNPRGYAKHGVNENP
LFDPNFLVDIN
>A0A1R4HCQ3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Crenothrix polyspora|TrEMBL
MVKQGFRPVGKDFPVFLHPDTHEEYALARTERKIARGYKGFSVYTSPDISLEDDLIRRDL
TINAMAMTPEGQLIDPYNGQQDLEQRIFRHISPAFAEDPVRILRLARFAARYHKLGFTIA
DETLVLMQAMVNDGEVDHLVAERVWAELLKALNEASPSAFFYTLKNCGALEKIFPEISRL
FGVPQPEQHHPEIDTGIHTMLCLEQATLLSSKPEVRFAALVHDLGKGITPPEIWPHHYGH
EKKGLPVLENFCKRLRIPNNFKNLAMHVMEYHTHCHKASELKASTLTDVLTMLGAFKANN
TLLDFVLACEADAKGRTNFENRPYPQADLYINAAKAATAIDTSELTKSGLQGAQIGEAIR
RLRIAAVAKERNILY
>A0A379YIJ2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serratia marcescens|TrEMBL
MESLFKLPVASGAAVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAIQAQCRDVDLIV
ATGDLAQDHSQEAYRHFAAGIAQLPAPCAWLPGNHDFQPAMVDALAAAGIAPSKQVLLGD
NWQVLMLDSQVFGVPHGELSEYQLEWMERCLQAHPERYTLLLLHHHPLPSGCTWLDQHSL
RNPHMLGAILLRYPKVNTVVCGHIHPRSGFGMAGSAPVGDAVYLRAIQAALHELHHRRRF
PRLALPRSAAGRSRRDAGVPPGKRRFPPRYGLGWILMPSTLLYLHGFNSSPQSAKAVAFK
AWLAEHHPDIEMLVPQLPAFPAEAAEMLENLVLERAGQTLGWSARRWAAITPPGCRSVFP
CRRWWSTRRSSRLSCWSTISAPTRTPTPASQYVLESRHVYDLKVMQIDPLESPDLIWLLQ
QTGDEILDYGQAVAYYTACRQTVESGGNHAFVGFEHYFPPDCGFFRAKRGLTDRSGTSL
>A0A2X1VKP0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oligella urethralis|TrEMBL
MTIIAQITDLHIREPGRLAYKRINTAAYLERAVNTLMTQKQKVDALIVTGDLCDFGRESE
YDHLQRLLQPLDCPVYLMPGNHDNREQLRRSFDTHTYLQQHHGEQIYYSVKIGVVQLIAL
DTAVLGKSYGELDKTQLQWLDRQLNQSQGAPVIIAMHHPPFNTLIGHMDKIGLLKGTTEL
AEIVKKYPNVERVICGHLHRSIDVRFAGTIASTAPSVAHQVALDIDPNAASCWVLEPPAY
KLHIWQEDGPLVSHLAYVDNYDGPYPFYENGQLID
>A0A0F0KF04|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium azadirachtae|TrEMBL
MTVQFGRYAPPTHTLVHLSDPHLLAGGAALGGRFDVDRTLARTLAAIENAVERPDAIVVT
GDLADLGEPDAYRRLRAAVAPVSERLGAPVIWVAGNHDERAVLREHLLDAPPTEDPVTGV
WDLRGLRVIALDSTVPGWHHGDVDAEQRAWLAEQLSEPAPHGTLLAMHHPPVPSHIPFFD
ILELRHQDELAEILRGSDVRGILAGHLHYSLHATFAGIPVSVASATCYTMDVASPGDQVN
GMDAAQSFQLVHVRPETIAHTVVPVVEAIPVDTFSPEWVARMERLTPEERLEAFSRKPGR
>A0A378WKC7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nocardia africana|TrEMBL
MILLAQLSDTHFDLDPRNADRVAAVLGYLDRLPRRPDAILVTGDLTESGTLAQYEQARKS
LTTDIPLYVLPGNHDDRANLRQTLLDGPAEDGPINQAVDIGGLTVALLDSTIPGSGGGEL
GERTYAWLDRLLAATPADSSVLVAMHHPPVPMYSTVVDPIRLADPQRLERTVAGDARILG
VLTGHMHAMGTTLFGGRPLVVAPSVASAIGGAWEVEEPGDVPIDYAPDPSVVLHAVADRR
LTSIVRTVPMGGRIRVQPR
>A0A0P1H437|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thalassobius mediterraneus|TrEMBL
MSKILVMTDLHITVPPETIIDLNPVERLHEGLAHAARLHPDADHLMLTGDLTHEGSAAQY
QALKPLLADLPWPATMLMGNHDLRGPFCATFPDAPVTADGFVQSVVDLPDVRLISLDTLD
TEAAVEHAGRLCPARLNWLEQVLRDAGDKPCLLFLHHPPFDTGFNGMDGIGLVNADELLA
LTGQYNVRHIFAGHIHRTITATVQNQSMTVFKSTCHQMPMILGQEGFGHSVPEPGAYGII
LTNGQDVVVHTEDFTLPDMQSRDFEE
>A0A8C8LYT2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oncorhynchus tshawytscha|TrEMBL
CTVGARNINKGEVNVVDLRKNIEYAASVLEAVYIDETRRLLDTEDELSDIQTDSVPMEVR
DWLASTFTRKMGVVRRRPEEKPRFKSIVHAVQAGIFVERMYRRTSNMAGLTYPPAAIAAL
KDVDNWSFDVFVLHEASSEHALKFLVYELLTRYDLINRFRIPVSSLVSFVEALELGYSKH
RNPYHNLIHAADVTQTHWLTELDILAMVFAAAIQTLNTLGQPTTFTFRPGVAILYNDRSV
LENHHVSAAYRLMQEDEMNILVNLSKDDWRELRTLVIEMVMSTDMSCHFQQIKSMRNALQ
QPEGVDKAKALSLMLHAADISHPAKAWKLHYRWTQALMEEFFRQGDKEVELGLPFSPLCD
RKATMIAQSQIGFIDFIVEPTFSVLVDTTEKIITPLIEDTLKSHDTGVRRSSLTGSGSVT
VVESVQKHSGRGSSQGVDQGLTTDYSLTGIDLKRVRHTLAEVIQHNKDRWKELSVQGIVV
FLLLLFFIFFFLVFFSLLNTFPSFSVMFFTLS
>A0A0H5S496|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Brugia malayi|TrEMBL
MDYSLLVKKRKKSNDNFANYTKFMKRGLLKTFEIPSSILLNYLLHLEHHYRDNPYHNQVH
AADVTQSVNVLISSPALQNVFSELEVLASIFAGAIHDVDHPGFTNHYLINTNSELAIMYN
DESVLEQHHLAVAFKLLQDSNCNFIVSLNKKQRQLFRKLTIEMVLATDMSKHMSILADLK
TMVEAKKVAGSSVLTLDKTDRIQVMQTMIHLADLSNPTKPIDLYSIWVKNIMEEYWRQGD
RERDLGIDISPMCDRNNITIAKSQVGFIDFIVHPLFETWADLVNPHAQYILDQLEFNREW
YQTRIPEEQEKHDVIMIEENDANVESTTIFQSSQQQSSPNEISNLKQFDSTKETKE
>A0A8M1PC69|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Danio rerio|TrEMBL
MEDGPPSTSCFRRFTDCFLGSSLTDEKVKAYLSLHPQMLDEFVLESVSSETVDRWLKRKS
STQPADDSSAKEVSRYQDTNMQSVVYELNSYMEQRLDTGGDNKLLLYELCNIIKTATKAD
GFALYFLGECNNSLCLFTPTGAKEGLPGLIPSGPITFGTTIAAHVAKTRKTLLVEDIMGD
ERFPHGTGQDSGIRVHSVLCLPILTAIGDLIAILELHRHLGREPFNLSHQEVATANLAWA
SVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALF
QVDHNNKELYSDLFDIGEENEGKPVFRKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADP
RFNREVDLYTGYTTRNILCMPIVSRGTVIGVVQMVNKLGGSAFTKTDENNFKMFAVFCAL
ALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLTLPSAIYKEIELFHFDIA
PFEELWPAIFVYMVHNSCGKTSFELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAI
LQKTTGIFTELERKGLLIACLCHDLDHRGYSNSYLQKFDHPLAALYSTSTMEQHHFSQTV
SILQEGHNIFSNLTSGEYEQVLEIIRKAIIATDLALYFGNRKQLAELLSTGALDLNNRAH
RDRVIGLMMTACDLCSVTKLWPVTRLTANDIYAEFWAEGDEMKKIGMQPISMMDRDKKDE
VPQGQVGFYNAVAIPCYTTLSELFPPSVPLLEACRENLSQWERIVQGEDVSAWSSTEEAE
VSETSDSGPVKVDN
>D7VFL5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactiplantibacillus plantarum subsp. plantarum ATCC 14917 = JCM 1149 = CGMCC 1.2437|TrEMBL
MRGRIELRPLQVIQISDLHLTPRGQVPAHGQQYDPWGKLANIIDDIRRLPTMPDLIVFTG
DLIHDGSADDYQRLHAIIHTMEAEFDCHVRVILGNHDRRAAFYEGYLPADPGPYYASRMR
IGNNDFYFLDSKVSGYEAGWLAPQQLQWLGKHLRQAPTKRAFLFLHHPLDGPTMTNMHYA
ILQNTPALLSVLRGHNLGGVFSGHVHFVSSYLIGDNILNVVAGSAAYAIDCHDPHHHYVH
EGSSYQIITIDRGQVGVTTRQLLHGKAVIDELTIPDTKFVGRAPQGYESR
>A0A7H4MSF5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella variicola|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQASGISPAKRVFLGD
HWQILLLDSQVFGVPHGELSDFQLEWLEHKLAEAPERYTLLLLHHHPLPCWL
>A0A4U9HTU8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serratia rubidaea|TrEMBL
MESLFKLPVASGAKVRILQITDTHLFAGEHETLLGINTYRSYHAVLDAVRAQQREF
>A0A6Q2Y753|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Esox lucius|TrEMBL
MAFPQRLPIGWLRHSLRRPFRSIVHAVQAGIFVERMFRRAYTAAMPNQPAEVVNCLRDID
TWNFDVFSLTTASDNHPLQTLFFELVTRYELNSKFKIPISCLTWFLEKLERGYAKHNNPY
HSSIHAADVTQTLHCLLLRTGLVHWLTELEVLASLFAAAIHDYEHTGTTNNFLIHTKSDF
AMIYNDRSVQESHHISATFRLLQEDQSNIFVNLSREEWMELRALVIEMVLATDMSSHLVQ
VKAMKACLQQTDGIEKPKALSLLLHTADISHPSKPWALHSRWTKALMDEFFRQGDREAEL
GLPFSPLCDRNSTLVAESQIGFIDFIVEPTFSLLTDMAEKIVIPLVEENPGPPDPCNRHS
NLWKESSRGLQWSLAHITSELVSFRSTWTRHTEDNKFKWRESNSNGTIHFDY
>A0A833J1Q2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Methylorubrum populi|TrEMBL
MRRIAHISDLHFGRTDTAVVDALAAELNRDPPDLIVASGDFTMRARRKEYVEARAFLDGL
TAPWIAVPGNHDIAYFKLFTRFFHPFGRYRRFIARDTEPTFLDDEIAVVCLNTVRTWAPE
TDWSQGKITRAQIARTEERLAALPEHVFRIVVGHHPFMPPPWDAEARLVGRADEALDAFR
RHGVGLTLAGHLHRHYARFAEAPETGAEPDSVAVDRGSAQAGGTRLLAVQAGSATSTRLR
GNEPNAYNRIVIEDGRATVTVRVWTGAGFEDVREDGSAPAAVEERPGATAPVGR
>A0A649YQU9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio sp. THAF191d|TrEMBL
MSTVFQISDCHLSDESSFQNLEKALNVANADSDCDTILLTGDICCGPKSGDYTKLLSFVS
QHVDSKKQVYAIAGNHDDIVLMKDELKGSLIQVVDQCEIAGRHFVFLDSSQKPIDAQHPL
GSGRIDNRGIAHLRKQIRKKKKPIVVVHHPVIRVGSEWMKAICLENDQQIFNILKQSGVR
EVICGHGHDHITCTKEGVTQYMAPATAYGFDHSIPEYNRSERIGMNKFTISKQTITVNEV
VL
>A0A812BYT3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sepia pharaonis|TrEMBL
MNRLHPTLNSCSVEEWLDSNPETANDYFLRKAELTLINKWLTNHGFQALQDYISGRKGSL
GQESITPTSPNDNKYSDQNFFPDSKHHRSNSKKHLRQDFAKSKLRNMFRTYCPSTCNTEA
RRSSLKELRQFRSLPPTSLNMLGMLIQSKIRLPRYPSKDIDMKRELFHMNEREFFLEIVK
EISNDLNPVSLSAKIIANISILVDGDKGSLFLVDRSIKEKPVLVSKIFDVHSGTNLLPST
TDDAITVHWGKGIIGYVAETGDTVNIGDASESYLSIYLSIYLSIYLSIYLSVHIYVSSKS
>I7K0T2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactobacillus gigeriorum DSM 23908 = CRBIP 24.85|TrEMBL
MEKTITQNQEAKIWVISDTHLIPASMHDEGAAFKRMETTSAGKDLNHQELALTAFVRKAL
KDKPNAVIITGDLTFNGELESAKRLAEIFKPLKKAGIAFLVVPGNHDINDGWSRTFLADK
QYRAQEISPQEWVKIFKDSYRYADHLDKNSLSYSVNLNNDYRFLMLDTNVYTDGYSTTAP
ATNGRLTKSTLEWLDGELEDAKKHKQKVVIFMHHNLYPHHKMIYQDFVLDNAEDLQKLLR
KYDVKLVFSGHIHAQNIIGPTEECPAVDIATGSFCVAEENYGETTFTPNKVSYQYHRFEM
TDNLNSEEKAQLHISNYNEYLKKLFAKGDHTHDFKNLFAKADWKQVNEFMFRMNWNYFVG
KSNYTKEEIQAQKNSKKFKLISEKIPMMKQYFAGFWDVKKDSRSLTISDNE
>A0A5C6BBQ4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Symmachiella macrocystis|TrEMBL
MNRRELLQSLAVGSGAALLSSGIGTPLLAADSSMPRKRTARLAHLTDIHLNEKRSAADGL
TKALRHVQALDDPPELLINGGDAIYDGLAVDRSHLESQWALWKNTWKAECALPVKHCLGN
HDVWGWDKPGSKTTGNEPGWGKQYSLDQLGLERGYYGFNVGGWRILVLDSMTADNETVYR
GELDAAQFAWLKNELTTTPATTPIAIISHIPIVTVGGLEFQEHVKQDPRKRRMLSHQDAT
ALVHLFRKHTNIKLCLSGHTHLTERISFSGIDFVNSGAVCGLWWKGDHYHTDEGYNVIDL
YDDGTFGTEYKSYGWTVG
>A0A0B1SL16|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oesophagostomum dentatum|TrEMBL
LFVYRRICDEDDDLAEVTPETVPDEVREWLAATFTRQNAGKKREKPKFKSVANAIRTGIF
FDKLFRKQQSVQCPIPGEMAELLREINSWSFNPFQLNEVSEGHALKYVGYELFNRYGFMD
RFKNSLGDLELLAVIFGALIHDYEHTGHTNNFHIQSG
>B8BX07|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thalassiosira pseudonana|TrEMBL
VEEFNLKPEVLCNFLRAVESDYSKENAYHNSVHAADVAQTTFALLRMGGDKYATTPLETF
SIICAAFCHDMGHEGKSNAYHVNSKSDLAVIYNGVSVLENMHAARACRLLTSAPADMNLD
ILAGLSAQQQESFRALITQAILWTDMSHHFSKLAHIKSKISTHGRTAEAVKFYQNIEGRS
MSTVLLFILHVADISNPAKPAPIFVEWCERSLNEFYEQGDAEKKAGLPVSPMCDRELTVK
SDSQIGFIKYVVRPSFVTLSDLVPNVVDVILPLLESNLQYWEEGQ
>A0A653ZRJ5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Enterobacterales bacterium 8AC|TrEMBL
MMKKMLALCLSGYSALAMAGFDVVALGVDGGVSDGNLTSYLIRSDNQTRYLALDAGSLLP
GIAKGLQKGSFPQVKPELAAPYTPQGYVFRQLIDSYFISHAHLDHVAGLIIGSPQDSKKT
LYAQADTVLTLRNHYFNWKAWPNFTDAGNGARLGTYRLQTVRPQQRFTLGLTGLSGVMYP
LSHDRYPSSMLLVSDREGSFAYFGDTGPDALEQSRNLDSIWRVLGPLIEQKQLKGMIIEA
SYPNGVEDKSLYGHLTPAWLLKELKNLQQYSGGEGSLKDLSVVIGHIKPSLKQGEDVRAT
IKQQLEQGNELGVKFILMEQGDRQQF
>A0A654TYW4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mycobacterium tuberculosis|TrEMBL
MAVTVELRDQAALGRVLRGTDVRAILAGHLHYSTNATFVGIPVSVASATCYTQDLTVAAG
GTRGRDGAQGCNLVHVYPDTVVHSVIPLGGGETVGTFVSPGQARRKIAESGIFIEPSRRD
SLFKHPPMVLTSSAPRSPVD
>B5YLF7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thalassiosira pseudonana|TrEMBL
MIGFGFMDNTIMIHAGHYVDCTLGVTFGLSTLAAAGIGQIFSGIGGVMFGDALEAVFQRM
SGAVNGSGVAASSTMSKAQRTMRVSRMAGLMGGIFGVALGCTLGLVNLFF
>A0A2K9JUN0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudoalteromonas sp. NC201|TrEMBL
MAWFDLELQFDKAQIRIGHFTDCHLFATPSGEYFAVNTAANLERTFAAMAKEHFDCVVFG
GDLTQDHSAASYHEFARIVRESELQCPVLWVPGNHDELALLEEISAGQIVRHKCITGPFG
QVLLLNSKGETPAGWCAKSHLGALKDKLNNSINNNTIAFAHHHPRPIDGYLDKHMLENGP
ALLNLLVDSEQVLGLFHGHVHNEYQQQFRTLPIYATPATSIQFDKHTKDWYQSDLGPAYR
VIVFSKSAITTEVKWLGK
>A0A2X1PLC6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Haemophilus influenzae|TrEMBL
MQDSSDEGYTRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEHWQAL
LLDSQVYGVPHGQLSQHQLDLLKETLEKNPERYTLVVLHHHLLPTNSAWLDQHNLRNSHE
LAEVLAPFSNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQPGWRE
IELHSDGSIRTQVKRIQQAEFLPNMQEEGY
>A0A0L6ZCU0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium homopropionicum DSM 5847|TrEMBL
MALYAISDLHLSFDAEKPMDVFGEHWLNHDERIKENWITKISNKDTILIAGDISWSMKME
QGKVDLEWIHRLPGRKIISKGNHDYWWNSINKLNNLYDDMNFIQNNFFTYEDYAVCGTRG
WNPPGEKYTKHDEKIYNREKIRLRLSLDKAKNEGYEKIIVMLHYPPVNEKFEESDFTKIL
EEYKVEKVIYGHLHGPSLRNVFEGMYNEIEYIMTSCDYINFDPVKIL
>A0A6T9Y3X2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Alteromonas macleodii|TrEMBL
MKYIFGFLIVSAISACSTISTNDSATEYNTAIKASESSVEPAFQLITLGDTGGIKDGNLS
AFLLRSLEEERYVALDAGSIVNGIDVALKEGAFDSLKSKPDDNLRANGNVLHNHVAAYLI
SHGHLDHVAGLLIASPDDNNKPIYALKSVNDIMGATYFNWQAWANFTNRGMEPKLNKYDV
VDLAPQHTTAIEGTNLTVTPFSLSHPLESTAFVIESDNDMFVYFGDTGPDDVEKEGKLGV
IWRYLAQQMRKKTLRGMVIEVSFDNSRPDNLLFGHLTPKWLIQELTRFYELVEDKSQVSD
INIVISHIKYSLKAGENPRSVISKELKQANKLGFNFILATQGQSLIF
>A0A6P8W9X0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gymnodraco acuticeps|TrEMBL
MSQTEDLQTQEKQQTEHETQIVEFEEHNYNDQVLFRLRGMQKYKSASQRLKGVLEQMDRG
VVDLQELRRNLELAAAMLDSVYTDETKRLLDTEDELSDFQAESVPSEVRDWLACTFTRKM
GVAKRRPEEKPRFRSIVHAVQAGIFVERMYRRTSNMAGLTYPPAALTALKEVDHWSFDVF
SFHEATGDHALKFLVYDLLNRYDLINRFRIPVQALVQFVEALESGYSKHRNPYHNLTHAA
DVTQTAHCLMLHTGLMHWLSELEILAMVFAAAIHDFEHTGTTNNFHIHTRHWI
>A0A1S8L484|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium felsineum DSM 794|TrEMBL
MRVYAISDVHIDYKENLEWLCDISNYDYKDDVIILAGDISHKINLVEKAFQILSKSFSEV
LYVPGNHDLWIRGNECKDSFMKFKQIKEVADFYNVHMKPVNFCNIAIVPLYSWYDYSFGE
LSEELIYKWTDFIACNWKDYDAPKVNNYFTALNDEFLGERNKRIISFSHFLPSIKLMPEF
IPNSMRYIYPVLGSNSLMRYIQELDSTIHIYGHSHVNVDKVENGVRYINNAFGYPREFRI
SAKKLKCVYEE
>A0A0B8PNE7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio sp. JCM 19236|TrEMBL
MKPCFWLPGNHDYKPSMGSVLPSAQIQACNHFLAGEKWQVILLDSQVTGLPHGYLEQEQL
AYLDDKLAEYSERHSLVLLHHNPLPIGSAWLDQHKLQKAVEFWQVLDRHKNVRAVLCGHV
HQEFQTEHHGVQVLATPSTCIQFKVNNDEFALDNLSPGWRHLSYIAMAA
>A0A086JBF9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii p89|TrEMBL
PVASVVGIVCAFLQMNRRSLLALTYNDNSVLEQFHSSVAFFLLHHHHLLLPSSPHCSTLE
RTRKRRSANHEAAAPSRKNEAGTQISTREASEAGNLELVGEDAAEQERGESVCAESLCDR
IEREEYYRDFRKEVIELIVHTDMTKHFSLLALFKVKRQTGGLDIVNNEEDRSMLLKMLLK
AADIGHATKAFDFHFFLSCCLIEEFHRQGDEEKKRGMVISPLCDRQQELRQIFSSQAGFL
QVVCLDFFSELADVARDLEHAQTLQLQSASAGPEGASGPRPASSGSRSHQRRDCAASRAS
GEEGRNFEASKDRQLVSRSFSSSASVPRLSSRKGFRRCLSTAEQPQPPLPSLTPSSPCRF
ALSSSAAYASGSLPSLLLSGAQSEDAGNRRAPPRLHPFRPLSGRGKTEPSSTALVREALP
PQAASAAAAVSCVCHQASVTGTSVFKRPCVGDIGSPPGLQRRLPAEETKAAAADSATGID
PASAGEKRRVFSSGVSHPFALPHGGPESRGSEKSGNACMRSLSSFFRGPKARKEDSDDDA
RARQKRSQTLPSSLSLVSASRCNGAQAFANRLPVRHCLDAEEPGGGRGGQDAPTGHRRIL
SRGGSLPPNYRSSEGDQGGPKSQGEAAGTIGALRAEPTRTGETSDGKLRGTEAATGAKNR
NAWSCPCETEESAATEGRESKDREAEAEAEEEERLCQGDFCEFCRNNSWSISRAASQHIA
SSTASAHSSSLLEACVTQIQRNKHAWEAMAEEQREPPRLLPADLLFGPFPRDGVGGLVRR
HLKRWSTISPS
>A0ZMG1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nodularia spumigena CCY9414|TrEMBL
MNQVSPISIAQITDTHLFASENHKMLGMPTIQSFQAVVDRLKELKSEVDLLLLTGDLSGD
GNPQSYDNLQTLLNPLQIPAYWLPGNHDCAIAMEDILNMGMVSRRKSFVRGGWNFILLDS
SVPGCLHGHLSGKTLDWLDSELKFLGNYPTLVALHHPPFPVNSAWLDSTTLKNPQEFFAV
LDRHPQVKLVLFGHIHQEFQRQRHQVEYLSTPSTGLQFRSKSPTLIIDSKYPGFRLLKLY
PNGMWETSVERVPYFHPLELAAKVS
>A0A8J5MST3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Homarus americanus|TrEMBL
MENTTSTPTSHHLDEQHQKRKRQVGEEEDELSEVEPDAVPQEVREWLASTFTRQLSTARR
KNDEKPRFRSVANAIRAGIFVERIYRRLSSATFLQLPPEVTKILKSVDDWQFDVWKLQEA
SNNTPLRCLAYELLNRYGLLHKFKMPPATLETFLTQVETGYCKYKNPYHNNVHAADVLQT
MHYMLSQTGLMNWLNDVEILATLMAALVHDYEHTGTTNNFHVMSGSETAILYNDRAVLEN
HHICAAFRLLRAEEHNVLVNLSREEYREFRTLVIEMVLATDMSSHFQQIKAMKTMLSLQD
S
>A0A177HX40|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces jeddahensis|TrEMBL
MSRLRSVATAAAAATTVNRRTLLAATGAVSLSAGIGYALRPGSAQAAAAPTDVPTAVSAS
SRQAPPAPLAPYERGTTLSTVSAPRSGAPGYRRLGDGPAWKRLVRSDLAAPRSGRTERRT
ALAAFVQFTDLHIVDVQHPLRYEYLRSQTASAWRPQEALSVAGAISLVERVNALRGAPAT
GAPLHFVMTTGDNTDNNARSELEWFLKAMSGGRITPNTGAPRRYEGVQNSGLKLYWQPDD
ALRDADKQLGFPHIDGFLEAAIREVRSPGLNLPWYSTVGNHDALPGGCYAPGDSFFADFA
VGGRKLMSLPEAQGAALWKNVKKGGDPKGQVFKEVLKSEARRMRSVTPDESRAPFTPAEY
LKAHLDPAHTGPGPFGHGYTAANLAAGTQYYSFRIADDVLGISLDTTDPGGHYEGSLGTA
QLKWLERTLKAHKDEYVIVFSHHTSKTMRNLNPDPGRAGEARHGGDEVLTLLGRHRNVLA
WVNGHSHKNKITPHGTFWEISTASHIDFPQLARVIELVDNHDGTISLFTTLIESAAPHAT
DFADLSQTGLAALYRELSFNAPGARSTLSGTPGDRNTELVLKKA
>A0A447XRL7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFATKARSPVRGKHLGKLPGVLEAIRPHQHEFDLIV
ATGDLAQDQSSAALSAFR
>A0A1E7XG58|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lentilactobacillus sunkii|TrEMBL
MDTTAAQNTPEGYQLNESGTFTFNTTCKVRETPEMSASGVADYTSGQSVNYDLKEKNDDH
FWVSYTGASGTRVYVPYANILKGTYFGTDTNSDDPIKSSDNGGGGDNGGGGNDDFGTRPQ
GGTDTGTPSFESEPITSAELVTAQIPVKGYVKLVDSGAYSRTQPLYSSPTVDHYEKGSTV
HYSAKLVADGRIWAVDPKGNYLTLGKTATPLQANALTGHHSKYDYVEDSSEKQPWNDIWN
YTSSLEERDTDDGSYSDLSSLRENPQIDLTPNDAESELITNLKNELAQVDQDNPTQDDIL
IGYITDTHFSSYKTPGTVRALRQMKLMSYIAHEVGLDLVVNGGDLNDGAAPSNWEMDDIK
RAVDATMLGRRPFIILQGNHDDDSGFARDDNHDENGYWSDNIIHNDVANTIRLSKFQQYL
NAESNANNALYGTYKVPNSKVNVVVLDGFDQPDDYGDLITSRTSFRHGWTHFSVEQQNWL
KSTLDTIQSNGEKALIFTHIMFHGQVWQSGEANEFAEIKQSDGSFYPNVFEGGNIKDIIE
NHASSVIGVFGGHTHRDDSCVEGGVTYLTTTCALPDRGDGQEARTINTNTEPAFDILQIK
PSAGKLFRHRVGWSNPSYFVDHIDF
>C0XJT6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lentilactobacillus hilgardii (strain ATCC 8290 / DSM 20176 / CCUG 30140 / JCM 1155 / KCTC 3500 / NBRC 15886 / NCIMB 8040 / NRRL B-1843 / 9)|TrEMBL
MIMVQCKIVQISDTHLTPAGAKPANHQHLDPEEKLRTVFDDIYNTNVDPDLIVISGDLIH
EGDAEAYADFHHMLDQEQERLMAPIKVILGNHDRTDQFYKGFLGKKRVATRYYYHESLEG
LECYFLDTKCGDIEQGYLDQTQLHWLKNQLQEYQRPGIIFMHHPLYGPPLQQMRYSILQN
GDDLLNVIDHTHVKAIFSGHVHFANSYVVDGILNVVADSTAYHINCANPHEHFVTDGTAY
NVITVDGDDIGVEQRLLYLGTKTINAFKIPNTDFVDKKILTRAWSNVLSKE
>A0A0D8HMD6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acidithrix ferrooxidans|TrEMBL
MDTSLERLSEGEVIQKGRSREFLALRAIEGQPHLDREDLHSKFASPRPSEPRARLVHITD
FQLCDPSSPTRFEFVNKLFGIASAKDLFPGHRAQETLIPFAIAQAIAYINELSSKSPIDM
CLITGDTIDNSQANEAETLLSLLSGEALELKKTFGQYFGVQSTEWNDDFFWHPDSIDDQP
KSELGYPTLEGLFKAINDKYPNQGLLVPWLLSNGNHEVLIQGMGACTEASNAFAVGGQKA
FDFGDNIDYLVASRKFEADPSTVFSKAERRPVEPSSQRRLIQSHEFIEMIRETPGLPSGH
GFLDKGGLEANFNFVHLDRIKGIVYIFLDTAVRSGGARGGIDNEQLEWLKSALAQSFDEI
QSPSPIGIIVSHHGLDEIDFNGNPEVTRSSLVDLIHSYRQIRLWFCGHTHENRILAIPNP
NRAGTGLFQITSASMMDWPCSIREASIYDYENGEIEVELTMHHSNSAKPKTITSIYDLAS
WHQLIAANSPYIGIGSCLEGAPEDQNVRLWFGAID
>A0A3G7UIB8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas synxantha|TrEMBL
MPSVSNVNPDASVLLVQLSDSHLFAEEGTALLGMNTRASLQRVIELVREQQPRIDLVLAT
GDLSQDGTLESYQQFRDMTRAIGAPARWIPGNHDEPQIMALAAVHSDLLEPVMDIGNWRI
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPNRHHLVCLHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQARALLWGHVHQEIDRERNGLRLLASPSTCIQFAPGSEDFQVSEQAPGYR
WLRLHADGGLETGVERLRDFAFTVDYGSNGY
>A0A1S8PBG5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium beijerinckii|TrEMBL
MALYTISDLHLGFNVEKPMDIFGDKWKAHSDKIKENWLEKITEKDMVLIAGDISWSLKET
DSKYDLDWINELPGKKIISKGNHDYWWGSISKLNKMYENTKFLQNNFYTYEDYAICGTRG
WMCPGGDKYTSKDEKIYTREQIRLKLSLDAAKNSGFEKIIVMLHYPPTNDKFEESEFTRM
IKEYSVEKVIYGHLHGPVLLGKVLNGYLDGVEYILTSADYLNFDPKKIL
>A0A084ZML9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Trabulsiella guamensis ATCC 49490|TrEMBL
MLLAHISDTHFRSQGQKLYGFIDVNAGNADVVAQLNALRERPDAVVVSGDIVNCGRPEEY
LVARQTLGALHYPLLLIPGNHDDKALFLEYLQPLCPQLGNDPQNMRYVVDDFATRLLFID
SSLPGHSKGWLTEETLEWLEAQLFEGGDKPAAVFMHHPPLPLGNAQMDPIFCENGHRLLA
LVERFPSLVRIFCGHNHNLTMTQYRQAMIATVPATVHQVPFHHEDTRPYYDMSPPSCVMH
RQVGEQWVSYQHSLAHYAGPWLYDENTSCPTQER
>A0A160TXQ7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MSDLHLVPSPELAHGLDAAKRLALGVESINQEYPDADFCVLAGDLVDRGDKESYQRLKAI
MQPLKIPYYPALGNHDDRDVFLSVFGRAHCDSNGHVQRVIDQKGYRVIVLDSVEAGRHTG
VLCDKRLAWLRDQLNTALNRPVIIIIHHHVNKVRFFMDDYRLENPNELLDVLRIHPDVRH
VISGHVHISTTGIIQGIPFTTVAGGHYTFAVSLGSDSRKKVKKLEGPAQYAVVLADEASV
TVHFHNYIDQHTALTKNN
>A0A3B0Z9T9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MPSILQFTDTHISIDPQGTLKGVNTRQSLTACVELAQQHSAAHILLTGDLSHDASKESYA
ALHSIITPLNLPVSAIAGNHDITLHMKKFLPQHWLTGECHIENWLCLMLNSSVTNKEHGF
ISDQELKRAKKVINNTQQDNILICLHHQPVPVGSPWIDAIMLQNAESLFGVLDGHSKVRG
ILFGHVHQNFQQQQGSLSIIGSPSTCIQFKSNSTEFALAHLAPAYRLLHLDRNGDISSEI
FYLDEMQSLEPDEAY
>A0A8J5EK92|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Yarrowia sp. E02|TrEMBL
MTFQVVVLGSSGGPIDRGTCSYLVRGSGAGGDDDTITSTGGSGQGYIAVDAGCFLSGIIN
VLEKQQLLTPEAYQQELLTESIAPHSPHSQRSWGIAYPPFDSRSLPYGGPTANAAHILSL
VSTICITHPHLDHISGVIMNSAAFSPQQTKRLAGLPRVIQALKDHVFNGVIWPNLTNEGV
DAVHLVQLLRLSEHLMSPDLAPGLTVTPYAVSHGHILGPAHHTQPSPCHHQPFKPSFSIR
TSEPSEPHRRSRRMPSSVIPPDSVIEMRRQSLMMEKRQLRASIASVSTHLHSPTSPSLVP
HRKSSSGNSSASSVGSVSPSSYPTSNPTSHPTPGPPLGTSLASYDSTAFFIHDSITNRVL
LMWGDVEPDSISYTPRNYLVWRKAAEYMQQGLLAAIFIECSFANPHDDALLFGHFSPRHL
IAELKYFASMVEGSEEDFHAMVGWEGLDETNEMDVENMDEEVSIPVPKRIPQTHAQGPHQ
PRPDLHLKGLPVVITHVKEDIYNEDPENDPRKVVLEDIIGLAKIENVGCDFIVATPGLSL
RF
>A0A143PRQ7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Luteitalea pratensis|TrEMBL
MPLLTGPRATRRQFLVTAGAAAASLTFTRLSVSAAQGPAHPLRLALLADTHIPANPADRS
RGFSPVDNLAKVVSQVLATPADGALVGGDLARLKGLPEDYARLHEMLAPVLAKMPTGLIL
GNHDNRENFRQAFPAVAGAAPALANKHTTTREAGGLRFVLLDSLLATDVTPGQLGSAQRT
WLASQLAGSSTPTVILVHHTLGGNDGELMDAERLFDVLRPHRQVKAIMYGHSHKYEVIER
EGLQLINLPAVGYNFVDNEPVGWIDSVWTDEGVDLTLRSIGGNQAGNGQTTSVHWAR
>A0A0H2YFP8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Yersinia pestis bv. Antiqua (strain Nepal516)|TrEMBL
MLLKYLSIKSASDKIKSGLLKTGVILSFSLFSSLSTAAFEVVALGVDGGVSDGNLTSYLI
RNDSQPLYLGLDAGSVLPGIARALEKGHFAAITDAMAAPLTRQGYIFRQSINSYFISHAH
LDHVSGLIIGSPDDSKKTIYASADTIDVLRNYYFNWRVWPNFTDSGSGARLGTYRMQVVR
PAQSLSLGLTRLTGEMYPLSHDKSPSSMLLISSNNEFFAYFGDTGPDDVEKSKNLDTVWR
KLAEKVTQQQLKGMIIEVSYPNDVADNKLFGHMTPTWLLKELKKLEQYSGEGQPLKGLPV
VISHIKPSFQQGQDVRKLILSELQQGNDMGIEFILMEQGDSQKFQ
>A0A3S5EV94|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acidipropionibacterium jensenii|TrEMBL
MAYFLQLSDVHLVAPGKKLYGTVDSTSLLRDLLDRLADAELAPSAVLVTGDVGDHGDAQA
YRTARTLIESYAGRTGCPVIWVNGNHDEIESFRSHILDGGVIDRVEHVDGVRLIVLDSTV
PGASHGLLTPDQLDWLRTVLAGPVEPTLLLMHHPPLRCPLPGLDRDMLRNRADLAELLEG
SGVSMVVTGHTHYAGAGVCGGVPVWVGGSTAAYTDVVPPRQRARTADYGSFSRIDLIDGE
AVAVSIPCQQMDTVLDFQAIIDGTIDKDLLAEIGIPARADEKDRR
>A0A5C6CK42|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Novipirellula galeiformis|TrEMBL
MPVHLPALNRRRLLQVSGASMLLCGRSSTAAEAAEVETDLVYLLNDTHIGEQQPEESPVP
SRLRKVVTELVNRPTKPVCVLINGDLALKDGQPGDYRLFAKLIRPLQDAGIETNLTLGNH
DNREAFFGVMKEQRAEYSPVESRHVAIVETEHANFVLLDSLQKTMVTQGTVGTQQLQWLA
SALDRFQSKPAIIVTHHNPRLGGDPLHFPGGLIDSEALWDVIGPRPWVKAYIHGHIHDRG
YANHRGIHILNMPATSYVADPQKSTTGWTTAKLTATGVTLTTHTTDEAHRWNGETKTLTW
R
>A0A1E3WHS0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio scophthalmi|TrEMBL
MDMLKTKLAVLVGCLSLGVAINASAAGFETVTLGSKGGIQDGNLTAFMLKSELDDNYVLL
DAGSVVNGLIVSEQKGAFADVKVPEDSKYTKVGYLLKEKIKGYLISHAHLDHVAGMIISS
PDDSHKPIYGLASTNEGLMNNYFNWSAWPNFGNEGNGFKLSKYTYTDLTQYQWQAVKGTT
MQVMAMPLSHSGGESTAFLLKDTQGDVFAYFGDTGPDAVEKSDALNKVWSALTPFVKQGQ
LKGIVIEVSFTNETPDKALFGHLTPNWLMKELTALESMAGKGSLKGLDVVVSHIKYSLKK
GEDPQVVIKRQLDTANTLGVNFLFPAQGDALTF
>A0A378ZDL8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pandoraea pulmonicola|TrEMBL
MSSRQHSQTGVDTDADVACPSLDGAEPAQASHTRVDASPLRISRRRAMACLAWAGAGILW
TLDGGVPRGLSLGGAAHAADTATRNALSFVQISDSHIGFNKAPNPDPAATLQSAIDRIRA
APQRPAFMLHTGDVSHLSRAEEFDAAQQIVNGAGLQTHYVPGEHDVIGDDGRAFFGRFAP
DTKGVGWYSFDQQGVHFVALVNVLNLKAGGMGYLGDAQIAWLAADLKGRSHSTPIVVFTH
MPLWSVYPAWGWGTDDADRALALLRPFGSVTVLNGHIHQVLQKVEGNVRLQTAMSTAFPQ
PSPGDGPGPGPLKVDAAQLRQTLGIRRVDYTSLDGAPLLADATLSS
>A0A517VQB2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia aquarii|TrEMBL
MKKKPLFPTESLGRRAFLKNGALILAGLSSNTIGLLSTRAVEVSQRGAVRIGLVTDLHYA
DKPAAGTRHYRETIAKLNEVIARFKTERPEFVVFHGDLIDSGKSLEQEKGHLQTVVKAIS
AIPFPKHYVLGNHCVDLLKKVEFLEGVGQKASYYSFDQNGFHFVVLDSCFKSDGTPYGRR
NFKWTDANIPEPELEWLRADLKQTKHPTIVFAHQPLDLKDSDAHAVKNSSVVRKILEESD
KVAAVFQGHSHHNKYSEIGGIHYCTMVAMVEGSGLQNNGYSTLDLFEDGSLVLNGFRKQQ
DYRWT
>A0A653VLW8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Flavobacterium sp. 9R|TrEMBL
MELFWDYRFKAIKTRITLLIFILLLQSCATHQAQFGKEATKTRTTNGIDTTKIAHTFYLI
GDAGNADLPLPQQTLELLSQKLASAHKNSTLLFLGDNIYPKGMPSDKEPEAKALAETKLN
TQLALAKNFKGQTVFIPGNHDWYSGIKGLERQAQFITTKLNDKKSFLPQKNCAIESVKIN
SNLTMIVVDSQWFLEDWNQHPTINEFCDIKTREDFFEELEDLLNKNRDKKVILAMHHPLQ
TNGSHGGQFSLEKQLFPLEQKIPLPVIGSVINLLRKTSGISPQDIQNKQYTILTKRIKTL
LQAHNNVVVVSGHDHNLQYIDHDNIKQIISGAGSKSEAARAIFPNDFSYGGNGYATLSVY
KNGRITASFFGNEKGKEQLLFETTLFDSDEKSATIAPKDFPKTTTASIYTQKQTRKKGFY
KFLFGTHYRKVYSTKIAVPTVTLDTLYGGLQPKRAGGGHQSNSLQLVDKDGKEYVMRALK
KSATRFLQAVAFKDQYVVTDFEDTYAEDFLFDFYTTSHPYTPFAVGNLADKIGVYHTNPK
LVYIPKHNALKEFNANFGNELYMVEERPSDSQVDNELFDNPDKIIATDDLLSNLHKDEKY
QVDEKAYIRARLFDMLIGDWDRHSDQWRWSAFKEGKNVIYKPIPKDRDQAFSKYDGALLS
LLMNMPALRHMQTFNSSIRNVKWLNREPYPLDLALLRTATKEDWIEEAKYIQNHLSDKEI
EEGFASIPNEIKGATINDIIQKLKVRMRDLPNYAKAYYEVLQKTVVIVGTNKKEQFSISF
PSKNEVEVVVSRLKKEGPEWWYTKRFDAKTTKTIWIYGLDDDDVFEVNGKNKSGILLRLL
GGQNNDSYTVTHGKNIMVYDFKSKPNTYNLDGKTKKVITDDYDTQYYNYEKPKYNAISGL
PFGGYNPDDGVKLGLIASYTVNRFKQNPFTQKHILKANYFFATSGFELLYNAHFPKALGN
WDLDVASKYTSPNFTINFFGYGNETINNDETFGMDYNRVRLRTLSVTPTIKKTGRMGSEW
NFAALIERITVEESTNRFINTPGVVNPEVFERQKFAGASASYSFENYDLPAYPSMGFGFS
IKGTWKMNLEELNRNFTALETKINLNHRLDKKGKLVLATILKSKILFNDHYEFYQGATLG
GDYDLRGFRNERFLGKRSFYQSSDIRWQLGKIKKSLLPLSYGLLGGFDYGRVWLPSESSS
KWHQAFGGGLWLNGLNVLTARITYFKSRDEEARLSIGLGFGF
>A0A0D6M4S5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ancylostoma ceylanicum|TrEMBL
MPGTHGDRRRVSADVKNALENDSDWTYDILQLEKVTEHHALTQLGFKIFDRWKVADALSC
NEDILHRWLCTIEAHYHAGNAYHNATHAADVLQATSYFLDSPTVAAHISENHAIAAILAA
AVHDLDHPGRGNAFLINTRQSLAVLYNDHSVLENHHVALAFQLTLQQNSNVSRFLCSQAR
ALLHCTLQVNIFSNLSREEFTSMRHAMVEMVLATDISRHFEYLVKFNKMNVVDVPDDARD
GNSLTICNMLVKCADISNPTREWSLCQKWAYRIVEEYFDQTKEEREKGLPVTMEVFDRKT
CNVPLTQCGFIDMFVREAFANFSEFANLGHLSAQLEANYEQWKSQTSSWTPANNVSLHI
>A0A1S0TGS0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Loa loa|TrEMBL
MRTSDVFNPEIYCIFQATSFFLDCPTVAHYVQEAHATAALIAAAVHDLDHPGRGNAFLIN
IRQPLALLYNDQSVLENHHIALAFQLTLQGTNDINIFAGLTREEFTTLRQATVELVLATD
MSRHFEYLTKFQQVVSNLK
>A0A448BTS3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas fluorescens|TrEMBL
MRWFAGNHDEREPMQRATEGSDLLEQVVDVGNWRVVLLDSSIPGAVPGYLEEDQLELLRR
AIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNPQALFDLLAPYPQVRCLLWGHIHQEFD
RQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGYRWLRLHDDGRLETGISRVDDVVFEVD
YDTAGY
>A0A5C5Z560|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Planctomycetes bacterium CA13|TrEMBL
MPLHIAPQNRRWFMQSAAALSAASLLVNEDVCGAVTPPVNANTFALLSDTHIPSDADTVA
RGVNMTDHLDSVIDQIAQLPIRPANLFINGDCAYLKGLPADYENLCRCIAPLDDLGIALH
ITMGNHDNRPVLYDKLTAMRPQSVAVMNKHASVVESEFANWFLLDTLKKVNVVTGEVGEL
QLQWLAQELDSRRDKPAIVMAHHTPQFSPPEPEKVWNGISDTDALFDLLDSQDHVKAFLY
GHSHKWNISERGHFKLVNLPAVAYVFDESQPNGWVSARLDRDGMHLHLHTHDVAHQKANQ
RVDILWN
>A0A1C5WZF6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Ruminococcus sp|TrEMBL
MNFAHLSDTHVLDKRSQTNQLLELVDDGKKLAQTITAAVNHPQKPELLLITGDLVHEGTA
EDYAYFKSILEDNCKGIPYVVCLGNHDRRQAFWEGFMGEKGVAKPYVETTMINGLRIIAL
DTSPVDGNEIGEMPQDQLDYLAEELKTAAPKGTIVILHHPPQGFVLKGFEGLCPVRDAFA
GIVEGTDVKAVLSGHTHYLSCHSKNGVTYATAASTAFSMDNAKKGDLDFIDACSYNLGRI
TEDSVYVGTETVNYQYKTLFTMKAADMEKMLKNQK
>A0A0G4JS10|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Brenneria goodwinii|TrEMBL
MLNAIQAQQYAFDLIVATGDLAQDHSLEAYRHFSRGIRQLSAPCVWLPGNHDFQPAMFDT
LDEEGIEPSKHVLLGDKWQIILLDSQVFGVPHGELSDYQLDWLERSLQSQPDRFTLLLLH
HHPHPSGCNWLDQHSLRNAHNLAAVLDRYPLVNTVLCGHIHQELDLEWHGKRLLATPSTC
VQFKPHCTNFAIDDVAPGWRYLDLMPDGRLETEVFRLAGSEFLPDMDSDGY
>A0A136WCR2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Anaerotignum neopropionicum|TrEMBL
MGLFAIADLHFSFSVEKPMSIFGANWEGHSEKIIHSWKREIQEEDTVLLPGDISWAMKEE
DAAADLEAIQSLPGRKIFLEGNHDYWWKSASRLEREYKGMRFLKNDCDRYENIFICGTRG
WLCPNDSRFTPQDKKLYEREQNRLRLSLESAMRKGAKEILLMMHFPPVNDKQENSAFLEI
MGEYPIKQVVYGHLHGKPSHDSGIQGEWAGIKFHLVSADYLNFCPKKIL
>A0A674JY97|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Terrapene carolina triunguis|TrEMBL
MDDCVTIKKKHLQRPIFRLRCLVKQLEKGDVNVVDLKKNIEYAASVLEAVYIDETRRLLD
TEDELSDIQSDSVPLEVRDWLASTFTRKMGMTKRRPEEKPKFRSIVHAVQAGIFVERMYR
RTSNMVGLAYPAEVIVTFKDVDKWSFDVFALNEASGEHSLKFMMYELFTRYDLISRFKIP
VPSLISFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMIFAA
AVHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILANLTKDDW
RAVFRLSPLYMYSYNMKHCFFQGDKEAALGLPFSPLCDRKSTMVAQSQIGFIDFIVEPTF
SLLTDSMEKIIIPLIEEASKSESSAFGAHRFEHFLLLLCVSL
>A0A086PVV4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii VAND|TrEMBL
MFDRRKHADFPKGQEGFLRFIIIPLYEEIAAVDTTDVVQTCCLQNAVANSERWRQLQSSP
EEFEAIDAKHQAIICVLKDRLEWRVQKNIAPTQRLLRASCAENQVRGSGVFFPTPECSGG
SGAPRASAPAEKRRESASASRDRDPGAADWKEETGNTAQALRERPPTEVAPQVDGEETCV
SDGVHERNRQDEGGGSEEGRRKAAGGDTEKQGDDRKDLLHFESRLTH
>A0A483APW2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|thiotrophic endosymbiont of Bathymodiolus puteoserpentis|TrEMBL
MKHFIQISDCHIDDNAQTMEVDSHINLAKVVDKIVTLQSDALLISGDLTHNGTPHSYKKL
KEILTPIETDIFVIAGNHDDSNNLASEFGACLFDCITLGAWDIINIDSVQLGKTSGFVTK
NALTTLDKQLQHSNTKYNLIVLHHPIVPMNSAWDDALSLENPQDLFAVLDKHPKIQAVLF
GHAHESAEFDKNGLKIIACPSTATQFNDERRIGFNYYTLFDDGCLDYETQWINS
>A0A1Y5RKR9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudoruegeria aquimaris|TrEMBL
MKLLQMTDIHLTAPDQTIGGRDPWQNFNAALDHALANHPDAEAIFITGDLSDWGETDDYR
RLAERIEALPLPVHLCIGNHDDRETFLGTFPEAADENGHVQKVVPLSLGHAVLLDTWGPE
SHAGHFCRDRARWLADRLAELPGPVWLFLHHNPVPTGIGPMDEIMLLDADRLADAIARHK
GKIAHIFHGHCHIPLSGHFRGIPFSAPRGTNHAGWPNFGAERLLAASDLPQSYGVILVAP
EGTMVHMIEFGYQGEIREEGSPHYADWDRATMVR
>A0A1V1PMB5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|alpha proteobacterium U9-1i|TrEMBL
MRLVLAQISDPHIRADSEAPTLALQRALAGAKDYGAQAILLTGDLVNDEKHQEYAELARA
LAAPSAPLYVLPGNHDDRALIRDLLPNHTYLPRGAHLSFVIEDLPVRIVMLDQIVPHQTH
GELTPELAAWLEAALAAAPDKSTLVALHHPPFATHDILFDRIGLHNQSQFADIIARHRQV
QRIVCGHHHRVAFGQVAHAPAIIAPSTSWIYGLALNEGQPIAPKTHEQPGWMLHVWTPES
GFVSHFIGL
>A0A0D6ISA0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas aeruginosa|TrEMBL
MSRHSNTPATDASVLLVQLSDSHLFAEDGARLLGMDTAHSLEKVVERVAREQPRIDLILA
TGDVSQDGSLDSYTRFRRLSAPLDAPLRWFAGNHDEREPMQRATEGSDLLEQVVDVGNWR
VVLLDSSIPGAVPGYLEEDQLELLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGY
RWLRLHDDGRLETGISRVDDVVFEVDYDTAGY
>A0A166I171|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rathayibacter tanaceti|TrEMBL
MSLRQAEYPRPHHFVLHLSDTHFIAGDGGLYGSDVDSEAQLRLLFDELEESGGRPEAIVI
TGDLADKGEPEAYAKLRAVVEPAAARLGAEVIWVMGNHDDRGAFRAGLLDQLPTTQPVDR
VHDVNGLRVIALDSTVPGAHYGEISGAQLDWLAEELASPAPHGTILAMHHPPVPSVLDLS
VLVELRDQSALAEVLEGSDVRSIIAGHLHYSSTAMFAGIPVSVASATCYTQDLNVPVGGT
RARNGAQAFNLIHVYEGTVLHSVVPVGASSEVSYVSANETQRILADHGVEIAPAPTAPLE
RDEALYPPVVEPVGVSA
>A0A085CMZ8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Elizabethkingia anophelis|TrEMBL
MKRRKFLAKVPLAASALMLGGTATNLLAATQKDKNINLKKKLLLTVAHITDVHLPADPKV
MERFVKCLKEVKTKKIDFFLNTGDSIMAVDRDNSTRQEVYDQWNAWDSCIKEIADYDMYS
CVGNHDIWWAGGKSDEMYGVPYAAKRLKMPNRYYSAKKGKWHFIMLDGNNSGVTLDPEQM
NWLKQELENIPQGEYALIMSHYPILTVTGTFEGGQHKDHVALKDLFYKHKDKVKGCLSGH
QHLLDRAWYNDVYYFCNGAMSGFWWGEGDKRSAKPFYYQETPPGYAILKFYDDGTFENEY
IVHHY
>A0A2X4ZXI1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella oxytoca|TrEMBL
MCPHGELSDFQLEWLEQKLTEVPERYTLLLLHHHPLPSGCSWLDQHSLRNAGALDCALAA
FPRVKHLLCGHIHQELDLDWNGRRMMATPSTCVQFKPHCANFTLDTVSPGWRWLELHPDG
TLTTEVCRLEGVKFHPDIASEGY
>A0A3G7TJ72|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas chlororaphis|TrEMBL
MPSVSTLTTDDPVLLVQLSDSHLFAEADGTLLGMNTRDSLQRVIDLVLEQQPRIDLMLAT
GDLSQDGTLESYQLFRDMTRQIPAPARWIPGNHDEPQIMAQAATQSSLLAPVVDIGNWRI
TLLDSAVPGSVPGYLQDDQLQLLASALSEAPERHHLICLHHHPVSIGCAWMEPIGLRNPH
ALFAVLERFPQARAVLWGHVHQEIDRQQGSLRLLASPSTCIQFEPGSEDFKVGETAPGYR
WLRLLPDGRLETGVERVTGFDFEVDYGSDGY
>A0A0F2J1I8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Magnetoovum chiemensis|TrEMBL
MSAVRFCPRPPPTPCTAWYTTKGEPPNVFSKCISTLSLAATLVPQEINQNWRHALLHNAT
LCTNGSMTKPNEVAEALRLAELYQLAILDTQPEEGFEAVVDLGVSAFNCSSCIVSFVDSD
RQWFKARRGFNSLHADETPRDISICTHTIKKDEPMVIPDCTQDERVKDSPLVTGSPWIRA
YLGVPIKTPTGARVGSFCLIDTSPRTWSSAEIKMAKSMAALVEVSLANRQQQAQGAYSRE
PIFQDGHRSDFAGHEQSYASWRRHGDESFIALSPNLEDWLCLSHSPRVSWAWFNGLIVRE
HRHDVELARELGNGQVFQYQIQLPNGRLLTLKERTYKTPEEEGEALTVGLLQNIAVAAQL
PRTAVQGRPNPLDTLKTNTLSFLAESTRGKLVLDLNFKLVQLGQVDDSELHRVKDNPSVL
DFIYEEDRENLVREMETVLGTRLKKKAFARIRLPDSKPVWARFVIDRPAPGIETSRKALV
LQYTKMVNESTMVDRNLFDQTLLGMTEKLGGLGTWFYHVDSGLLKVSDQFKAICKATELP
LGSIFELTELLTRLTGKNMASTLIECINNRQAAHIECEVNFERLTGQRWFRFSFQPISNG
LGSSSGLYGSVEDITHTKHLAQELSRKSTALNQVLNTLTDGTLELDEALQVEAMDAKARP
LILGKETFIHQAAIADVLPGLDLLEFRKRQSELRRQGTTGDFEFFNTRTNRWLRLKFLPR
GDGLTILLRDITQRKAMYRDLFMVGSAIEQINEVIMVTNDLGSNATSFQCIYLNSAFENV
TGQAVAKWLGRNPYPLIADRLPLRDFRKLLVSLLKREKLTIKTRYETDNGAHVPCEILVS
PFVDKETGTPWSLIVFRPSST
>A0A518AEN3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia panareensis|TrEMBL
MSSTTPDSRISLGRRAFLQHGALLLTGISAAPLSRLAAAAEAKQRGAVRIGLVTDLHYAD
KPPAGSRHYRETLAKLKEAKAQFEKDQPDFVVFHGDLIDSGKSLTQEKKHLETIVKAISA
MPFPKNYVLGNHCVDQLTKAEFLQGVGQQESYFSFDRGGYHFVVLDSCFKSDGTPYGRHN
FKWTDANVPAPELKWLQADLKQTDLPTIIFAHQPLDLKDTDAHAVKNSSEVRKILEASGN
VTAVFQGHSHRNKYSEIGGIHYCTMVAMVEGSGLDNNGYSTLDVYPDGSLVLNGFRKQKD
YHWS
>A0A0W0WV08|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Legionella nautarum|TrEMBL
MENDFSTKEKLKILQITDMHLFSTNPCLFGINPNKNFNEVMRAVFNQEIKDTDFILLTGD
LSQDETADSYQYLVESFKHCEKPVFWISGNHDNEKLMTEVFSQLASFKRGKFLELNDWIF
LFINSKLEGSENGYLSQDELKELEKKLKLCHKNVALIMHHHPTPVNTPLIDKYILNNREE
LWEIISNTKVKLIITGHVHGDYTLAKNDIKIECSPATCYQLKKGTSTLEIDHAVGYKIHY
FDKSEYYSKAVVWEFS
>A0A517VKE5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia algae|TrEMBL
MPVHLPAQNRRQFLFTLGAGFVTCSTGLLAEEQNTPQSDIVYLLNDTHIGEKHPPKSSIP
THLREIVTELVELPQKPACVLINGDLALRDGQPGDYQHFAKLIQPLQEAKIDTHLTLGNH
DDRDVFYEVMQAQRPSAPPVKSRHISVVQTKHANFFLLDSLHKTMVTQGTLGKEQRTWLA
NALDAHADKPAIIVTHHNPRLGGDPLHFPGGLTDSEELWELLVARSQVKAYIHGHIHDRG
NAEHKGIHILNMPATSYVANPDHSTTGWTVAKLTPTGVTLTTRTNIKDHAWNRQTKTLAW
R
>A0A086LRY7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii RUB|TrEMBL
RGVRRLSTAQLGRI
>A0A086LJH2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii RUB|TrEMBL
MFDRRKHADFPKGQEGFLRFIIIPLYEEIAAVDTTDVVQTCCLQNAVANSERWRQLQSSP
EEFEAIDAKHQAIICVLKDRLEWRVQKNIAPTQRLLRASCAENQVRGSGVFFPTPECSGG
SGAPRASAPAEKRRESASASRDRDPGAADWKEETGNTAQALRERPPTEVAPQVDGEETCV
SDGVHERNRQDEGGGSEEGRRKAAGGETEKQGDDRKDLLHFESRLTH
>A0A090P8S7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio ponticus|TrEMBL
MLKTKLALLIGCLSFGVNAASFEAVTLGSKGGIQDGNLTAFMLKSEQDDNYVLLDAGSVV
NGLIVSEQKGAFDDVKVPQESNLTKVGYLLKEKVKGYLISHAHLDHVAGMIISLQMTAIN
QSMVCLPPMKR
>A0A090RYS9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio maritimus|TrEMBL
MKIIHLTDTHLGYIGQKIYQRSPVIALEKAVESINQEHSDAEMLIITGDLAHAGHPEAYE
TLEKTLSELTIPYHLVIGNHDDRAVLSEIFPTFELDENGFGQKVIETQKGVFILLDTMIE
GTHAGVYCEQRLDWLENEISKADAANRPVYLFMHHAPFDTGIPALDVIGLEKQASARLAD
IFDEFGNIKHLFFGHYHRPIAGSWRGVAFSTLRSMNHQVRLDMHCESMIQGCFEEPQYCV
VLLQDDATVVHYHDYMHSSEHFDIGDPLKAHV
>A0A0H5NUW7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nocardia farcinica|TrEMBL
MILVAQVSDTHFDLGARNNERVERVMAFLADLAHRPDAILVTGDVTESGKPEQYAEARVA
LQADIPVWAIPGNHDERAAFRTELLGEQPSDSPINHVHRVGALTVIMLDTTIPGEPGGRI
EEDTYRWLREVLADAPAAGPIVLAMHHPPARLHSPIVDDIALAEPDRLADVVAADPRIRA
VLTGHAHSAAATTFAGRPLLIAPSTASVLGGAWEVELPHRVMDYAPDPAVALHVFDESGS
MTTHFRTVPMGGFLGVAPV
>B9Q8H3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii (strain ATCC 50861 / VEG)|TrEMBL
MHRLLDWDFHVLALPPASAVLVTRDLLTQFALKANMDIPGEILMAFSVAIYKNYRPNPYH
NFYHALNVTQVLCLLLALPDVAAQFSPIDYLVLSVAALGHDLGHPGANNLFMTRFDCWPS
RIYQNVSVLENYHAASLFQILRHPAFNVFCSVSPTNFAPIRKRIISAILWTDMAKHFDVV
AKLQAKIQGEMVLAEGIIVTLTKPYLEGLLLHAADISNPMMDFELCRDWAFRACDEFYQQ
NKMEEMGGFPPSMPSFEHFDEYNVAKCQVGFIDAICKPLFNSLALMFPAQLGDRATQLQK
NRCVPVIIFPT
>A0A447JC81|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salmonella enterica subsp. enterica serovar Daytona|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQQQL
A
>A0A212KCE5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Desulfovibrio sp|TrEMBL
MRILQLSDTHLRGDHSLSFRVVDTRRCLDEAVAHVKNLTQQPDFIVITGDLADSGDLNAY
HILHDELSPLGVPVYAVPGNHDRRDRLREVMPHWCPAKEDIAPYLCYTVEEENLRLIMMD
SMSPGSHSGHFPAETGDWLERELAKRPDTPTMFFMHHPPFVTGMGAMDEPFENMERFAAI
VERNPQMRLCFGHMHRPIVTEWHGRIAMTAPAVSMQIDLDLSPEGGDTFRMETPGYLLHH
FDKGVWNSHICQIAVQATFAGPYPFAGSVNPTQ
>A0A5E6NW84|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Gammaproteobacteria bacterium|TrEMBL
MKHFIQISDCHIDDNAQTMGINSHENLIKVVDKIVTLQSDALLISGDLTHNGTPYSYKKL
KEILSPIETDIFVIAGNHDDSDNLASEFGACLFDRIALDAWDIINIDSVQIGKISGFVTT
NALTALDQQLQHSNAKYNLIVLHHPIVAMNSEWDDALSLENPQDLFAVLDKYPKVQAVLF
GHAHESVEFDKNGLKIIACPSTATQFNDEQRIGFNYYTLFDDGRLDYETQWINS
>A0A1J5R0T2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|mine drainage metagenome|TrEMBL
MILCQISDLHIKRKGALAYQRVDTAGALRRCLSAIARLRPAPDAVVVTGDLVDMGDAEEY
AHLREILDELPMPYYLLVGNHDHRDALRQAFPEHVWLGRDGFVQYAVDLGPCRLLALDTQ
DPPHGGGRLCERRLQWLEQELGRAPAKPTILAMHHPPFVTGIGHMDKIGLPREDRQRLSE
LVSRHPQIERIVCGHLHRPIQRRFGSSVASTCPAPAHQVAFDLDPESAPGFRLEPAAMQL
HAWIDDEGLVSHLVNIEEYPGPYPFFQPGGGLID
>A0A1J5T4Z1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|mine drainage metagenome|TrEMBL
MNTNETDMDRRKFLQLACYGGAIYASGIGLAACSSTGAGKSAESDFFFVQLSDTHWGYSG
PANPDARGTLPKAIAAVNALPVDPDFIVFTGDLTQLTLDTKVRRERMAEFREQVGALRVR
NIRFLPGEHDASADRGDAFREFFGATHYSFDHKGVHFVALDNVSDPTGSLGDEQISWLEK
DLDARSKDVPIVVLTHRPLFDLQPQWGWATRDGAKALEVLQAYPRVTVFYGHIHQENQHM
TGHIPHYAARSLIFPLPAPGSGPDHLPLPWDTAQPYRGLGWREIEARGSARSIEEREHPV
G
>I9KY16|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactiplantibacillus pentosus KCA1|TrEMBL
MRPLQVVQISDLHLTPRGQVPVHGQQYDPWAKLANIIEDIRQLPTSPDLIVFTGDLIHDG
SADDYQRLHAIVHTMEAEFDCHVRVILGNHDQRAAFYEGYLPADPGPYYASRMRIGNNDF
YFLDSKVSGYEAGWLAPAQLQWLGKHLRQAPTKRAFIFLHHPLDGPTLTNMHYAILQNTP
ALLSVLRGHNLGGVFAGHVHFATQYLIGDNILNTVAGSTAYAIDCHDPHHHYVYEGSSYQ
IITIDRGQVGVTTRQLMHGTKVIDEFTIASTKFVERTPKGYQSR
>A0A199XSN5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Flavobacterium succinicans|TrEMBL
MELFWDYRFKAIKTGITLLIFILLLQSCAIHQAQFGKEAAKTRTPNGIDTTKIAHTFYLI
GDAGNGDLPLPQQTLELLNQKLASAHKNSTLLFLGDNIYPKGMPSDKEPEAKALAETKLN
TQLALAKNFKGQTKFIPGNHDWYSGIKGLERQAQYITTKLNDKKSFLPQKNCAIESVKIN
SNLTMIVVDSQWFLEDWNQHPTFNESCDIKTREAFFEELEDLLNKNRDKKVILAMHHPLQ
TNGSHGGQFSLEKQLFPLEQKIPLPVIGSVINLLRKTSGISPQDIQNKQYTILTKRIKTL
LQAHNNVVVVSGHDHNLQYIDHDNIKQIISGAGSKSEAARAIFPNDFSYGGNGYVTLFVY
KDGRVTASFFGNEKGKEQLLFETTLFDSDEKSATIAPKDFPKTTTASIYTPKQTQKNGFY
KFLFGTHYRKVYSTKITVPTVTLDTLYGGLRPKRAGGGHQSNSLQLIDKDGKEYVMRALK
KSATRFLQAVAFKDQYVVTDFEDTYAEDFLFDFYTTSHPYTPFAVGNLADKIGVYHTNPK
LFYIPKQKALKEFNANFGNELYMVEERPSDSQADNELFDNPDKIIATDELLHNLHKDEKY
QVDEKAYIRARLFDMLIGDWDRHSDQWRWSAFKAGKNIIYKPIPKDRDQAFSMYDGALLS
LLMNMPALRHMQTFNSSIRNVKWLNREPYPLDLALLRTATKEDWIEQAQYIQNHLSDREI
EEGFASIPNEVKGKTINDIIKKLKVRMRDLPNYAKAYYEVLQKTVVIVGTNKKEQFSISF
PSKNEVEVVVSRLKKDGPEWWYTKRFDAKTTKTIWIYGLDDDDVFEVNGKNKSGILLRLL
GGQNNDSYTVTHGKNIMVYDFKSKPNTYNLDGKTKKVITDDYDTQYYNYEKPKYNAISGL
PFGGYNPDDGVKLGLITSYTVNRFKQNPFTQKHILKANYFFATSGFELLYNAHFPKALGS
WDLDVASKYTSPNFTINFFGYGNETINNDETFGMDYNRVRLRTLSITPSLKKIGRMGSEW
NFATIIERITVEESTNRFINTPGVVNPEVFERQKFAGASASYSYENYDLPAFPSMGFGFS
IKGTWKMNLEELNRNFTALETKINLNHRLDKKGKLVLATILKSKILFNDHYEFYQGATLG
GDYDLRGFRNERFLGKRSFYQSSDIRWQLGKIKKSLLPLSYGLLGGFDYGRVWLPNESSN
KWHQAFGGGLWLNGLNVLTARITYFKGRDEEARLSIGLGFGF
>A0A165M9J6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodococcus fascians D188|TrEMBL
MKSRMAEYPRPHHCLLHISDTHLVDGGGRLYGGVDSELRLEQVMTDVRNSGVRPDALVFT
GDLTDKGEAGAYEKLRALVEPVAEELGAQIVWAMGNHDDRATFRRTLLDAEPSGQSIDRV
HDVDGLRIVTLDTTVPGKHHGELADEQLAWLADALATPAEFGTILAMHHPPVPTVLDLAV
LVELIDQPRLADVLRGSDVRSILAGHLHYSTTATFAGIPVSVASATCYTQDLNVPAGGLR
GRDGAQGYNLVHLYDDTVVHSVVPTGSYDTVGEAVSAEETARRLDAAGVTIADSARRKLF
SDA
>A0A6P2F520|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Variovorax sp. PBL-H6|TrEMBL
MLIAQLSDLHVDAADSANTRRVRSALAALAQVRPQPRLVLVTGDLTQHGRPQQYELLRNL
LGDCGPCALVPGNHDDATLLHRLFPDVSPPRGGMLRLEVEGLRLLLADSCVARQDHGELG
KNLLQSMALELDCDPRPTLLAMHHPPVPAHVPAMEGMGMRQVAAFQEWVARRACIIAILA
GHYHQAQFATLPAGCPVIVAPSVAPPLVADFTAPSFQVEAKAPAGLLHLWKQRRLSSHFF
ICDLPAANPLQK
>A0A2X2CS05|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas luteola|TrEMBL
MATSPDFLAAPLVVQLTDSHLFSSPEGRLLGLDTRYSLEQVVERVRAEQPTIDLILASGD
LAQESTPEAYQSFKELTACLDAPARWLPGNHDKVKVMQTFCAGTDLMDPVLDMGQWRLIM
LDSTINGAVPGRFDQEQLELLEKALSEAPDRHVLVSFHHHPVQVGCQWMEPLGVLNPEAL
FEVLDRYSQVRVILWGHIHQEFDQIRNGVRLLASPSTGLQFEPNSVDFKVGMQAPGYRWL
RLLPDGTIETGISRVEGVDFNVDFQGSGY
>A0A0S4TPU9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ralstonia solanacearum|TrEMBL
MVELTAARGNQTVTVVQITDPHLFADRDAELMGYRTYPMLSKTIDAIRGHDFRPDACFLT
GDISQDESADSYELARFELERLGIPVFWIPGNHDDRGRAEAVFGQSDHIHRLSKLTTADW
DFIHLDTCRRGADEGYLSDPDFERFVSDVEASARKGKQIAVVMHHHPVPSQTPLLDGYML
QEGERLLRFLDDHRQVRLVICGHVHGDYQFQYGSQTIEVCPATCFQWEKGTRTAKAEDWR
GFRIFEFSSAGYQSALISV
>A0A425HXX9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii CAST|TrEMBL
MHISCVKGRIVARQIDNVFTVIFAIEVLGKFVSYGLEYLQDPIESFDTIVVLTSFTLLVL
GFYVSGIGLLRILRLLSALALLHKYPDSKEKRPELSAGNSSKLEKASSIVEGLLTNVHIP
KYFKTELEWVWDSILANKVYDSHVVENEEEEEDQATETIIAGSDASRKTQAAVRASRAQS
RASKLPHGSSSMVVGTTNGRISGQILETLREPDPRMMDAALYKSETRNLDPLTATVGGMK
NSPSMFAKGSKSSNMMGSSASKSFRTERNKKAIDIISVLYQASQITGAEQEQVNEAMRPF
DEWQWDALHAGDVCDMNLLPVVFVRAIATFPTIMTKFNFDLDRLFDFLKVVQTSFQKNVK
FHCAAHTADMIQAMHYFLTIGKLGALLSEYDVFLCHFCALVCHFGHPGVTNTFLVKSRHP
RAIRYDDESVNENYVASAISCLVAREEYNFFGDKLPLWQVFRLHMIDILLNFDISKSAHQ
VAMFRTKVSIKFTASTPADKQLLLTILLRAADYSFTCRQLALYSKWKDRMIDEFFAMGDT
EKQLALTVSPFCDRELTNVDKCHVAFAEVAVKPLMTVLVLGLAPHLQKDVLDTLEANQKN
LMQKLDKSD
>A0A425HSB1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii CAST|TrEMBL
MFDRRKHADFPKGQEGFLRFIIIPLYEEIAAVDTTDVVQTCCLQNAVANSERWRQLQSSP
EEFEAIDAKHQAIICVLKDRLEWRVQKNIAPTQRLLRASCAENQVRGSGVFFPTPECSGG
SGAPRASAPAEKRRESASASRDRDPGAADWKEETGNTAQALRERPPTEVAPQVDGEETCV
SDGVHERNRQDEGGGNEEGRRKAAGGETEKQGDDRKDLLHFESRLTH
>A0A245ZER8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sphingomonas mucosissima|TrEMBL
MSMKLFHVSDVHFGAEDPKALDWFARCVADEAPDAVIMTGDLTMRAKPREFDAGGKWLLS
LGVPVTIEVGNHDLPYYWDPLRRLLSPYKRYGAAERLIERTLDLPGVSIIPLKTTARAQW
RWNWSKGHVSSGALRDALDLAEAVPKGNLIFVAGHHPLIEGGTRGTAKTRNGEKALAALA
DAGVHAILSGHVHDPFDKPVQVGDWTVRMIGAGTLSKRLRMSPPAFNEIRIDGGRFETLA
RTLSPEPKHQISRTSRAGLS
>Q98NZ2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)|TrEMBL
MKTLVHLSDLHFGKTESQLVDAIAAEVRAVDSDLLVVSGDLTQRARKDEFLQARAFLDSL
PGPRIVVPGNHDVPLWNVFARAMTPLSRYRRYIEADTDPFYADSEVAVVGINTARSLTIK
DGRINVRQLKAATEKFAHMSDDITRIVVTHHPFEGRDLESDDGIVGRADLAMHAFSRSGV
DIILSGHQHLHRAGSSARRYLIDGYAALLIQAGTAVSSRLRRAANSFNIIRIEHPRISVE
CRAWQPSQSGFETSASYSFRQGPGGWKPT
>A0A1P8W9T6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Fuerstiella marisgermanici|TrEMBL
MRILQLTDLHIFAAPNVRLKGIPTRESLQDVVVHVLATEQPFDHVIITGDHTHDERPESY
QAVRDILAPWSDRLSQIPGNHDDRAVLRQVFSDRVARSDSDRINFQRTAGDWLLLGLDTH
VPGEVAGNIEERQIAWLTERLSASDQPSVALFLHHPPVEIGSEWMDAIGLNGRELLQEVV
KNDDRIRLICCGHVHHEFQSTIGNAAVFTTPSTGIQFDPAGATPNFAADAPGYRVIEFDG
ADFETHVGRLPTVKYVPDND
>A0A8D0DZY1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salvator merianae|TrEMBL
MTEPSNRKDGFKKCRSATFSIDGYSFTIVANETGDKNARPLSRFARSKSQNCLWNTIIGG
LTGNLKEKQKPTIICDPRPPEEILADELPPVESPEALVKTSFRLRSLVKQLERGEASVVD
LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDSVPSEVRDWLASTFTRQMGMMLKR
TEEKPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIGVLKNVDKWSFDVFALNDAS
GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV
HYLLFKTGVAWLLHLDWDRNTNKICVKDFYHLRRNQRMFILLFCRSDTAILYNDRSVLEN
HHLSAAFRLLQDDEEMNILSNFSKDDWREFRTLVVEMVLATDMSCHFQQIKAMKNALQQP
EGIDKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDKEAELGLPFSPLCDRK
STMVPQSQIGFIDFIVEPTFTVLTDMTEKIVTPLIEEASRSGMTGFRRSSLNSISPSEVK
RSSVKSTGSEGSASLNCSLLTVDFKCFKATWTEVVQQNREKWKAQATKEEKAKKEAEDNL
QQGTDEKKTDDNEGKKLTDEPTGVKSDGSKEGHSGACKSTEASKSNVNGTRQTGGSRHDA
SQGKNVTQAEKASEPNSTAGEQKRHVQNGKPVDRFMQWGSYSIRPPIRSSKKPNFASTST
SFPPFQKKSEDYLVRYKLLDQRGRMKKIQHISQHWNRK
>A0A0N5A1N0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Parastrongyloides trichosuri|TrEMBL
MIRDAVKALSSNELYTPQLSKIKDSERLNNGYYDGLIRVQPSLSRQRKRSVVDAFHTNKR
NTDSRRRISTDVRNALENETNWDFDIIHLERITDHHALTYLGMKIFDKWKVHEHLNCSQE
IIGRWFQVIESHYHNDNSYHNATHAADVLQATSVFLESEVVAENVVDTHAIAALIAAAIH
DLDHPGRGNGYLINTRQHLALLYNDQSVLENHHVALTFQITVPDKNINIFQNMNREDYNG
LRQAIVDMVLATDMSRHFEYLTKFQQTMLNLPDEENRDSSSLAICRMMIKCADISNPVRK
WKISQDWAFRIVNEYFEQTKEEIEKGLPVSLLHFNRETCNVPRTQVGFIDMFVREAFTHW
CGFAQIPELLTILEDNYEKWKEQVDSWKTSDNEKLLLK
>A0A086K965|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii GAB2-2007-GAL-DOM2|TrEMBL
MKCADLSHCSVPWSQHFQWCQRLSVEFYDQGDEEVARHLPMSPLCDREKHSEVAKSQLGF
MSFVAVPLFEELMAIDGTGNIEKYCISVMKTNASHWEALSSAAVPVPLLGEAPSPDVAPP
LLHLIDGSGAAAVHPGSKAAEIANRYASSTVTTLDLTCLVYRTQLNRARRSSQQSGRRVS
EGTSA
>A0A1R4GJC8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Psychrobacter piechaudii|TrEMBL
MPVSDSSVEFVNYPPTQITTEDGVINILQLTDPHLYLDPDTETAGINNYQSFTACLQQAL
NENIRCDLILLSGDLVNEVKPEIYQNIYQLLEKTGIPFVCIAGNHDVTDELDTHLPFSER
RFEAHKPNTLLLSRHCLTLNDWRLLLIDSSVPGEIYGTVGNKNLNWLSQKLANSHHPVII
AMHHHVLPMDSAWIDHHITKDAEEFWQQVEGYPAVKAIVSGHVHQNFESQRAGIKVYATP
STCYQFKPKSDNFAIDDQAVPGYRWLSLTKQGIIKSWITSLENKKA
>A0A514EX41|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Raoultella electrica|TrEMBL
MLLAQISDTHFRSHGQKLYGFIDVNAANADVVSQLNALQERPDAVVVSGDIVNCGRPQEY
EVACQILGNLNYPLYLIPGNHDDKALFLEYLHPLCPQLGNDPQNMHYAVDDFATRLLFID
SSRAGTSSGWLTDETIKWLEAQLFDGGDKPATVFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTLTQYRQAIISTVPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDEKISCPTEER
>A0A6J8CLI9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mytilus coruscus|TrEMBL
MSINNVFTIVSAIVVAVQSSSNIQTYRINAKVPGGSINEDIVVDSVNHLMTVNVGNVHHL
QSDCPSTINLHDFEKGKVAMKNIDTGECLVMDTKENLKATIELLDKITRLKITHDIEAEK
LVDVYPTTYERLLEEAGEHIIEFCKGYELFYGEIIEHQEGDKRQEKKKSGKI
>A0A1C9W462|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbulbifer aggregans|TrEMBL
MSEESKGRVHRLVQFTDPHIGGRPNYQLLGLDTGRTLDEVLARIARDQGNADLLVATGDI
TANGSEAAYGRFLKRMQSVHKPWYWLPGNHDSVQRMMQLAPGRFVEELALGHWRLLLLDT
SVENQICGGLSETQLHRLEASLQREPERPVLILMHHQPVPVGSDWIDGHMLREGHERFLT
VVSAAPQVRALLWGHVHQQFDSHLGHIGLHATPSTSVQFTPGSGPFSVDEEMPGYRWLDL
FEDGTYETGVERVLVSEYSVDLTSGGY
>W8V629|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae 30684/NJST258_2|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFID
SSHAGTSKGWLTDETISWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A226PSX7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Colinus virginianus|TrEMBL
MRSLVKQLERGEASVVDLKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDSVPSEVR
DWLASTFTRQMGMMLKRTEEKPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIGVL
KNVDKWSFDVFALNDASGDHALKFIFYELLTRYDLINRFKIPISALVSFVEALEVGYSKH
KNPYHNLMHAADVTQTVHYLLFKTGIVHWMTELEIFAMIFAAAIHDYEHTGTTNNFHIQT
RSDSAILYNDRSVLENHHVSAAYRLLQDDEEMNILSNLSKDDWREFRALVIEMVLATDMS
CHFQQIKAMKNALQQPEG
>A0A8D1EC78|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sus scrofa|TrEMBL
MLCYIQLRSLVKQLERGEASVVDLKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDA
VPSEVRDWLASTFTRQMGMMLRRSEEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPP
AVIEALKDVDKWSFDVFSLNEASGDHALKFIFYELLTRYDLISRFKIPISALVSFVEALE
VGYSKHKNPYHNLMHAADVTQTVHYLLYKTGVAVSTDKNAEIALKMGWSDPAILYNDRSV
LENHHLSAAYRLLQEDEEMNILINLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTAL
QQPEAIEKPKALSLMLHTADISHPAKAWELHHRWTMSLLEEFFRQGDREAELGLPFSPLC
DRKSTMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNNISSS
DAKRSTVKSSGSEGSAPINNSVIPVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAE
EKARLAAEEKQKEMEAKSQAEDGAAGKAEKKASGEAKTHPVNGTRTNKSDNPRGKNPKAE
KSAGEKQQNGDLKEGKNKTDKKDQSSVGNDSKKADGKSITRIIFFRKVCSLMQAC
>A0A0N0XKP1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Amantichitinum ursilacus|TrEMBL
MQNAINRRLFLQLAGAGGVVWVTGCASTPGNTASADFYFVQLSDTHWGFKGAAINPDSAG
TFPKTIAAVNALNPPPDFVVFTGDLTHISDDPAERRQRLKQFKAMAATLTVPVVHYMPGE
HDASLDNGAAYQEFFGATHYSFDHKGVHFIALDNVSDPHASIGAAQLQWLQADLATQAKD
ARIIVFTHRPLFDLYPSWDWATADGAQALALLEPYSDVTVFYGHIHQEHHQMTGHIAHHA
AHGLMFALPAPGSQPKRTPIAWDATAPYKGLGYRRVAEAKGSAATLTELPLQGA
>A0A060QCD2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Asaia bogorensis|TrEMBL
MGFSRHDAGGPMISYRLPANLLPALPSSMIRLLLLALMVPIATVQAHEFDVTVLGAAGGL
EDGNLSAYLVREAGTSSGVLLDAGTVLNGIEKADAAHAFDDIDLGPDPSASRSGVILHRV
IKGYLLSHAHLDHVAGLVAISPEDPGKPVYALPSVLSVLQDDLFNHRVWPNLGDRGVKPA
FGLLHYHDLTPGQTMPLSGTPLSVTAYPLSHGGVESTAFLLHSGQDALLYLGDTGPDAIE
PGGHLAALWHEVAPLIRTGHLRGIIIECSYDNRRADKQLFGHLTPRWLLSELAALQAIAG
VSMTGFPVLVSHIKPLLDAGPTAQTRIRNDLDRDNRLGFHFTLARQGMTLRF
>A0A086L3R3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii p89|TrEMBL
MKVSPHRTSERGSSPTGGENGKHRFTQSGALRRQSAAPGGAKRSTMTGFLKAEPNPGSET
QDLEATQRRLKSAHRRTMLPTWILTGLSLAYVLFEGGRLLYETTLQQWSEEAILHIDKEI
FFLHDFAAGFYSLAEQLTSDYCFLNFMNAHSPPAAPTSTREEVQNLISGYAPSFCSWIKD
LYFFEEPLADTADRSTYQLLNTTYICGERFADLVQRINGNMVEVVQNYTLVKMRLIEMLA
PLVDNRNWSPHLLCDLDFSAGDLWACHDGLTALEQLRGQLSGYLGREWHLYSPILSIVIV
FILATLFFSRRHAFNAIFHTRFESLWAMLQQIDQVLQRRLENMVVIMQSVIDDRMIGRLK
VVSGIQSLLLSSESPAVMRQFYRVMEHCTFELIESLNLASQYVKLEMQSSTEGREMVNIR
LLLDGCIQVYKNETRANGTSISCVYAPTVPTALAIDKLRLRTVLLQVLRFALLEGKVTNA
EVKLTAKKVFLGKAPSTIETEKRNDLKNFDTQISIKCKMESAMTFSAVELLDSAYLRLRR
GKGIGFIYAKKVLRELNGDITITTTDSNEVIYDLYFQAMGRFHVKDFHVAFGTVKNAVAL
TMNVQQAKGYSQLAAVADLVGVKVIHVTSVAEAVEHMLSNRGHRIVSVFFKDPAGVIRSQ
LSSALPQSNSRNIPLVEVVAEGDILTRERLEESFRLANPSDTSREVAIEIQERGKRGSTT
QGRLLLRESHAFRQSKIVPIEEPLTTSDCVTAMAIGAASFLSNRQASKDLLRNLSYGRRS
FWDSLVTAFTANTTRLDRRRKWVNEIWRQVEFDAWKPVQQFRGSVYPADRLFHKVSNMPI
QNKYYAYFVAGRINEVGFATNVIDLYKNMVLDQRVYKLPEEKNMSFYELAQTRAYLLETG
QKNECLGADYNEDYLGKLLGAQIDPMDTTALVKKVYEEFEVKSEIKVPEEEEPAGQEDEL
PTAERTTEEFKWGNIPEYTVPSCITASVARMDTVLCLAPSIASEARLNTYRENAPSIAVE
FIFSWDFDISSLQPEMSAKLAYELLIWCADKAHISVPRETCEKFVLSVQQNYSAMPFHNF
NHALHAAQ
>A0A0W0VT66|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Legionella lansingensis|TrEMBL
MSTNSPITLVQLSDLHFSGEKPLKNHPKLPAEGLANVLKHIETTIPEEKIIILTGDLVAD
PDPALYQELASIFRTLPHTVAAIPGNHDSFEMMKEHFFGYNISSKTVLSIGKWLNILLDS
SHSGLVKHSGRIINSDLEMLENTLTQHPNQHILIFLHHPPIAFGSEKFKKIILENAADFN
SIVQRFEQVKAVIFGHAHTEFSLLRQKILYLSCPSTWAQFDRSQDDLFFMPTPSAYNSYR
LYDDGSFLFMTHYCWS
>A0A0P8W7V1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oxobacter pfennigii|TrEMBL
MNKRFFTLISILSIFFISACGSTSKDIDPVNKIQSGKDINFFVTTDIHYLSRSLRDDGKA
FQKFYTTGAGKQLNYIDEIMDDFIYEIEREKPQVLIISGDLTTNGEKQSHIDLAGKLQKV
EDMGTFVYVIPGNHDISNPWARSFKDDSQYLASTVSPDDFRKIYRNFGYGEAIMRDKDTL
SYLAAPSDDLWLLMIDTNLYKNNSILGAPQTDGEISKDTYEWIKKCGAEASEKGAELIGV
THHSLLDHSEVIREGYTLNNNKEAIEVFKNLGININLSGHIHIQDISSYKENDYNLYDIA
TNALSVYPNQYGRIKYSPADSSYSYTTSKLDVEGWAREVKSNDQNLLNFSTYSKDFFGKL
AYDMAYNSLSGDAQFSEEDKKSMSDVMEILNLRYFAGTEHLNSQDVVDSEGFKKWLGVPP
SFHKSYILTIISDNDTDDNNLYIGPNNQ
>A0A422PNN4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Trypanosoma conorhini|TrEMBL
MKTESSPLGLWDEQKEEAKIKKILICVAAASAGDLFVVVFFTGEGRDGGCANVPQAFFGG
PSATLRSRRCILLPLLRALCRRARLLRFSIFFSALYFLLPCAFAFLFFAAPHTNARGVGA
CAILQPCGFVEMQLGPQKRTFARPPALGGAPVPATEFNAILRIQKIRQTLCGVVASRGAS
SERASTPQQEVRGQSPEAQAPAPPVSAAGRFLLSSQRRVEELMRENHRLELLCVSQEETV
RELREVLASGRGQQAEGVADASAKRERSQRRNTPSLSRRSQAAPRASECVGAADAAGAPQ
SSPVPGGLVEAVQQLVDAAAWVFPRLLSDAGASGDGAEKGLETACAVLGFVADHLAEWDR
LASESAEVRAAHALLSQTLLNLEAESVEWRATILAVVQKLQATQAEQRRCLQEKDSRIDA
LGARADALAADVAGAVEERDRCTHRCEDLERSIRLRVEEQASERGEAEQLRRECELLRGE
LDSLRASAPKDAVAAAGVAAFDAGEQRTWTQVDVEDFQTTIACLTNERDALQSRFDALTH
TLAEVNGRVLSLEEEKRELSERLRTLQEDAEQRVQEIAQLKRAAAAAAAASSHETPAAAR
AHCPAEAHRRWFLQPVECCRFDGAELLTPVVDVSPVLCALGADVSAFADSNEHVRSPGLF
FHMGSAIAQDLGLFRDLPSTSLDAWKRFLLQLQTGFRDALFYTADHAAACAQFFYALLLR
SGMVPHMGRAELLAAVTAALCMQYGHPGVSGCLLSAAQDPAAAGVHSCILLQRRRLQDLG
DLLAQDPFHFLDDAPATHSLLDEVRDLLLPEECDGQCSGVMRACLGLLSAGPLQLESRAM
RCRFVQLLLRLSQYAFCMRAFDVHERCAEKWFSLMQRQSQVAAELGIYGFDVPHTTPTAA
EAQLLLIEFTVLPLCRIAAQAFPSLQACEEALRANHATWSLRAAQHPTDGVAFELLEASL
RPTSASPDVEGAARDAAAASGTDPRALDDARVSAAVRVASGSLLVNTSCFLASQKEMLAA
YEDNATLRRLLEALLAPVETLPAPQDVAA
>I3IA47|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cellvibrio sp. BR|TrEMBL
MGAQQSESLLGLNTDQSLDDVLQLIQTSEVGFDHLLCTGDVASEAHRDCYQRFETNIRRY
FSQPMSWLPGNHDSAELMAANQERLGIQSRLVMLGQWVLVLLDSSVPGQVYGQLAASELD
FLEHALRAHRDKHVIISLHHQPVLVGSVWIDQYIVRNADAFFQLIDAHTQVKIVTWGHVH
QEFQQQRKGVTLLATPSTCVQFKPKCDDFTVDTQMPGYRWFDLRGDGSFDTGVLRVTNKQ
YVIDYKSAGY
>A0A1E1VDI7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bosea sp. BIWAKO-01|TrEMBL
MIIAQLSDFHVRPHGQPAYGIVDTNAATRRAIDAVLALEPRPDCVLVTGDLCDCGLPEEY
EIVRAELARLPMPVYAVPGNHDRREVFAAMLGQVGLGQAGSSLTKSGFLHYVIEDYPVRL
IGLDTVIAGEDGGEICWEREAWLAERLAEGRGRPTLIFMHHPPFAVGVDGMDIMPCRVSP
DFVALIGGHPEIERVLCGHYHRPIQRRFAGTIGFVAPGTAHQVALDLRPGTENRFVMEPP
ALAIHVWKPETGLVSHIQPIGDFGPRRPFVLDPAYPGKQQAVAAHV
>A0A378JHP6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Legionella busanensis|TrEMBL
MKIAHISDLHFGMHNKQILNAFMEDIAEHKPDAVIISGDITQRAKVWQFEQFKEFISRLS
TLVLTVPGNHDIPLHNPIARLFFPFQNYKHYVTNDLTITYSNDEVRILGINSVNPYQIKD
GQLSHKNLATITRYFDSQDTKLNILFFHHNFDYLEGLHKPLENDQEFLRYLKQSTVDIVC
TGHLHYAHLGLIEKNDNYSCLVLHAGSLMCERSKDGLNSYYIIENNQQACRIHWRVFCES
QFMTRTIHHINFANKHALLESIMQPAEEV
>A0A378J5L2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Legionella donaldsonii|TrEMBL
MRIIHISDLHFGMHQDHVREAFLAELALLKPEIIIISGDLTQRAKTYQFELLQSFLRCLP
GEVLVVPGNHDIPLYNLLGRLFYPFKAYKKYIAKHFNAQFSTDSLAILGVNSVDPYQIKD
GQLSSKIIKKIKQYFRTEKKAVNILFFHHNFDRIEGLHKPLENEMEFLSFLRSSDIDIVC
TGHLHYAHVSLIKKDNMKPCLILHAGTLLCTRSRDALNSYFVIDLEGGQCAIDWRVFVKE
QFLSRKNYSIKLSEVNALLE
>A0A0R2Z0N7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas synxantha|TrEMBL
MPSVSNVNPDASALLVQLSDSHLFAEADTTLLGMNTRASLQRVIELVREQQPRIDLVLAT
GDLSQDGTLKSYQQFRDMTRPIDAPARWIPGNHDEPQVMAQAAVHSDLLEPVVDIGNWRI
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPNRHHLVCLHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQARALLWGHVHQEIDRERNGLRLLASPSTCIQFAPGSEDFQVSEQAPGYR
WLRLHADGRLETGVERLRDFAFTVDYGSNGY
>A0A378MV61|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mannheimia haemolytica|TrEMBL
MLNTQVVGMPYGELSYSQLKWLEEKLAQYPQRFTLVALHHNILPTNSAWLDQHSLKNSNE
LSEIFAKFKNVKAIVHGHIHQQVDDIWHGIPIYATPSTCIQFKPNCDQFTLDLQPQGWRE
IELHENGTIETVVKRLNSNDFLPNVNAIGY
>A0A1W1D859|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MIQISDCHIDDDPESMGVDTHANLKKIIKVIAKKHFDTLLISGDLTHNGTQNSYRLLQQI
LSPIQSNLVIISGNHDNIENLNKTFAQNLIHKFSLGDWEIITTDSTQESKTSGYLSKQEL
TKLDQVLQETTAKYNIVVLHHPIVSMQSNWDDALSLENSDELFNVINKYPKIKAILWGHA
HQASEFNNNNVALISCPSTALQFDGEKRIGFNHYTLHDNGNLEYRTQWI
>A0A160TI52|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MIRLFHVSDVHFGREDRAAIAWFDGLVQVEKPDAVIMTGDLTMHARRREFAAGLAWLQGL
GVPVTVEVGNHDLPYFNPVARLFRPYDRIGAIERLIERPLDLPGVAIVPMVTTARAQWRL
DWSKGHVSSRALQRALALVEAAPKDALVFVACHHPLIGAHEQMRSSTRNGADAFKALAAA
GASAVLTGHVHDPFDVVREAGGRKIRMIGAGTLSERTRDTPPSFNEIRIENGRFDVVLRR
LGPEPDMVLPKEKIE
>B2J817|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MSVYQGSYGETTDLIIGVHNQENLELQTNSAPVGALATRKGNFSTFLAPLTQDTFKQVVQ
DVEQKLQIVHQTLSMLDSQGFETLLQEMLHSITLKTGELLGADRTTIFLLDEEKQELWSI
LAEGEGDRSLEIRIPADKGIAGEVATFKQVINIPFDFYNDPRSHFAQEQEKRTGYRTYTM
LALPLLNEHGQLVAVVQLLNKLKSGNNHAAPLAERVDTKGFLSCDEQLFQEFAPSIRLIL
ESSRSFYVATQKQRAVAALMKAIKSLSQSSLDLEDTLKRVMDEAKELMNADRSTLWLIDH
DRHELWTKITQDDGSTKELRVPVGKGFAGIVAASGKKLNIAFDLYYDPDSDTAKQLDQQN
GYRTCSLLCMPVFNADQQLIGVTQLVNKKKTGDFPAYNPADWPKAPDCFQASFDRNDEEF
MEAFNIQAGVALQNAQLFATVKQQEQMQRDILRSLSNGVVSTDKTGLIIAANESAQRLLG
LGIDDRLEGKLVTDAIGIKEGDFSKWYQDALHAVDLKGRQQYYPDRTLVTTGTESHSINL
SINTIADASDHEQVRGALVVMEDISDEKRLKSTMYRYMTQELAEELLKLDDAKLGGDRKE
VSILFSDIRGYTTLTENLEAEEVVSMLNEYFESMVEAVFKHKGTLDKYIGDAIMAVFGSP
LALEEHAWMAVQTSLEMRVRLHEFNQRRYVDDKPRIKIGIGINSDTVISGNIGSSKRMEF
TAIGDGVNLGSRLESVSKQYGCDIIISHNTFKPCQDNIWARELDYIRVKGRNEPVAIYEL
LGLRSNPIESEKLQVIEHYHKGREYYLKRDFNRARAEFALVLAADNQDKAAMLHLLRCQH
WLQSPPTESDWDEGVWTFQEK
>B2J646|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MRIEPIIKVSKINHYYGTGQLRKQILFDISTEIQAGEIVIVTGPSGSGKTTLLNLIGALS
SVQEGSLTVLGQELNRANNKLLENVRKNIGFIFQAHNLLTSLTASQNVQMSLALHGGISK
REAERKAQAILEMVGLGERVNYYPNQMSGGQKQRVAIARALVTNPSVILADEPTAALDKK
SGRDVVEMLQYLAKQQGCAILLVTHDNRILDVADRIISLEDGFLTSSKNTSSNNSHRLAS
LKGELINHVEDLSLKDFLSLLQQVTGEFQSFLSLIDNEATGKCLEEIIEAITLKITHLLQ
AERSTIFIVDDTSGNLWSEIIQSNRKKILKVGITAHFGVAAHVAATRECLNIPIALQDYR
YSPAIDEQTGYQTRNILCLPILNSQSKVLAISQVLNKIGNNCFDRKDEQLLGEFSQQISA
IFDMWCHLQKLHKTSISGKY
>A0A238IZJ3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Boseongicola aestuarii|TrEMBL
MAKILVMTDLHITEAGTSIIGLDPALRLSETLAHAVKHHSDASRLILTGDLTHHGTPPEY
DRLKDTLQDLPWPVSLLIGNHDNRAAFRQAFPNVPTDADGFIQTTIDLPDTRLILLDTVD
ETPDVPHAGILCPDRLAWLQTALAESPNPCLIFMHHHAFDTGFAGMDRINLANANEVRTL
L
>A0A7Z8ZFS4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Raoultella terrigena|TrEMBL
MLLAQISDTHFRSNGQKLYGFIDVNAANADVVSQLNALQERPDAVVISGDIVNCGRPEEY
EAARQILSGLNYPLYLIPGNHDDKALFLEYLHPLCPQLGSDPQNMRYAVDDFATRLLFID
SSRAGTSSGWLTDETIKWLEAQLFDGGDKPATVFMHHPPLPLGNAQMDPIACENGYRLLA
LVERFPSLTRIFCGHNHSLTLTQHRQAIISTVPGTVHQVPYFHKDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTQER
>A0A0P1F1V3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thalassobacter stenotrophicus|TrEMBL
MKLVHISDIHLTAPGERMGGLNPHKRFAQALDDVRSQHSDAVRIIITGDLTHWGEPAAYA
TLVDALNDLPCPVRLLIGNHDDRAAFLAAFPDQPKDSAGFINHAETVDGTRLIYLDTTAP
CNHAGHFCAARRAWLERELKDCTRARLFMHHNAMPLGLPAEDKIALVPEDRAPLAALLTK
YRDRIDYIHFGHVHAPVHGTWCGIPFAAVRSTGNQSLPDLSEQELLQGAPMAPSYAVILA
QDTGTTIHEIPFTWDGPIFSSGTEWDDWAKPVAAE
>A0A7Y9L7C7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mucilaginibacter sp. E4BP6|TrEMBL
MFRTKTVLVVVFLFVFAITAHAQIKPAASFKIVPLGVKGGIDESNLSAYMVAATGTNNYI
CLDAGTLHYGIEKAISNGVFNIPAEQVLRGYIKDYFISHAHLDHIAGLIINSPDDTAKNI
YALASCIKTIQKDYFTWESWANFADEGEAPQIKKYHYEVLIPDSITAIRNTAMTVRAFPL
SHSNLTSTAFLIGSNDAYILYLGDTGPDEIEKSHNLHNLWLAIAPLIKANKLKAIMIETS
FPNEQPDKTLFGHLTPHWLMNEMNNLADLTSKNQLKGLNIIIIHVKPPQLNINKLKAQLQ
AENNLKLNLIFPEQGKLIML
>A0A379TK93|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salmonella enterica subsp. arizonae|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYGALQEAGISRLSTC
>A0A1I7VIC8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Loa loa|TrEMBL
MDLITRWFDAIEAHYHAVNPYHNATHAADVLQATSFFLDCPTVAHYVQEAHATAALIAAA
VHDLDHPGRGNAFLINIRQPLALLYNDQSVLENHHIALAFQLTLQGTNDINIFAGLTREE
FTTLRQATVELVLATDMSRHFEYLTKFQQVVSNLKDHDENENNTSLTISRMLIKCADIGN
PTREWELCEKWAMRIVEEYFDQTSEEREKGLPLTMELFDRNVCNVPLTQCGFIDMFAREA
FTSWTQFSNLPNLLTQLEMNYEKWRQRTADWNPSKNMQLCDERPLTS
>A0A0M2GYC7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium ketosireducens|TrEMBL
MDAASVQFGQYPPARRTIVHLSDTHLLGGNRPLGGRFDTEQNLLRALEAVEGLGIRPDAI
VFTGDLTDLGEPDAYRALRAAVEPVAARLGAPVVWVAGNHDERTALRRDLLDLAPSEEPV
TSVHDLGGLRLIALDTTVPGWHHGDLDDAQLAWLRAELADPAPLGTILAMHHPPLPSHIP
LFDILELRDQSRLADAIAGTDVRAIIAGHLHHSTSGTFAGVPVSVAAATCYTMDLARPAA
SVNGMDAGQSFHLVHVYDDTITHAVVPVVDAETSDFFSPAWVAQMAALSPQERLEAFSRK
PTAS
>A0A0M6ZNQ7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseibium alexandrii|TrEMBL
MALIAHITDLHLRPRGLACYRVSDTNMLAERAILALNGLTPRPDAVVLTGDLTDKSDPRE
YALARQILSRLAMPVFMIPGNHDGSADMRREMSGFPGMDGDVDGKLCYTAEIGDVRLIAL
DTNIPGKPNGELGTPQLNWLSDRLSDDNRPTLIALHHPPALSGIQHMDAIGLNDANALAE
VIGPHKHIQRLLCGHLHRPIIAEFAGKIMTLAPSTGHQVVLDLTEDGPPMFNFEPPAYFL
HHHTPQAGTVTHMAYVEAYPGPHHFFADEGVSWPGDDA
>F6IUW3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactiplantibacillus pentosus MP-10|TrEMBL
MRGRIKLRPLQVVQISDLHLTPRGQVPVHGQQYDPWAKLANIIEDIRQLPTSPDLIVFTG
DLIHDGSADDYQRLHAIVHTMEAEFDCHVRVILGNHDQRAAFYEGYLPADPGPYYASRMR
IGNNDFYFLDSKVSGYEAGWLAPAQLQWLGKHLRQAPTKRAFIFLHHPLDGPTLTNMHYA
ILQNTPALLSVLRGHNLGGVFSGHVHFATQYLIGDNILNAVAGSAAYAIDCHDPHHHYVY
EGSSYQIITIDRGQVGVTTRQLMHGTKVIDEFTIASTKFVEHTPKGYQSR
>A0A380QSB3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Yersinia ruckeri|TrEMBL
MESLFELPMASGARVRILQITDTHLFAGEDETLLGVNTGRSYRAVLDAVIAEKHPYDLIV
ATGDLAQDHSVAAYQHFAKGIARLPAPCVWLPGNHDFQPAMVDVLAEANIAPSKQVLVGD
NWQVILLDSQVFGVPYGELSEHQLEWMERCLMAYPQRYTLILLHHHPMTSGCTWLDQHSL
RNAHVLAAC
>A0A086PPQ1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii VAND|TrEMBL
MGTPENCMQTQGNGETFVPFGTLAEQMNAAARQPPPRDPEGGARHACVEVESREDRDSRR
ESASHLSAVLPLGEGGEATSPEGTWISRLSWKRSAPRRRSSSFSRRWRSWKRDEGESEEA
SDVDDYASSRRTSSECAKDARKKRRSRFLLARRTSLVGRVKRRSTGTRRRGAARWVRQTS
SRARSFVAEKAVATFGAELDLYTGRNERRKELRRTSKTSIAFSSEASGLRGVASVGSKSH
PFSLLPLKFRDEQLESEYVATLNELCSSRVYTCFGVFVLVLVVLWPSMGTSFSLSLHQAE
GIGCRLFHLLWIAKLISWFLLLITVSLRNKLRWISQKIIPFATMQITWGFILVIAFCCAY
VTDFIERHNDKISQINQVYETHLVRGPLNRRKLVTAIKTVSADRPVDLGLFTLAEDFVAS
LSLLMLLTMVESLVTVVCLGSLIPTRTRYTWPLYLVAPFLCPIPCVICNAIAPAFILGST
TVVYYFVSITVWLVGFIVRYSSECSQRVAFYSRVAPRKEIENLKNSLRRSQRHGGCTAVE
ELQHTAKCMEAVVKQLEGTCMAAARDFVPPVDAEGRANVQELALLLTKLQDVLRGTDDLY
SVRHTPFMLETTTGQELLELYGTNMSRQATLSWAGGGGGSVGVPTPALSPSTSLEGPRFY
GQSKSPKCFAPSLPSAFGVLPGLNAIHQPPLRQHTDPVRTQTPSLISPVFRRRYQRHTSD
RGAKKTAWPASSPARAFLRGSAASSCSLHCGPSPSIAEAPGEEEEAAAELKRRDENRMEG
KLSPSDPSRESKRRAKNSRRSCVATASVTSEVVAGPTDKLAADNCYRENAVGQNSYRKVQ
VKVDTLSACLRKRKAGSSAPHSPSAGCAESHHGDACSCHQPEGEGASPCSGQRACLEGFD
GSSDNAESVQEDRQKSGKALDTVWAPQSGSEPSSMLVVPSANWASGDSKKPLKSVAGRGA
SRQKVGCLGLRCFGRRSRRPAFHPPASLYNARPCGSLHHRRSTFPAVNVPGRAFAPSLAE
VGIDASPFYSLSPHGGEGVFQHARETPLAGRSARWSLRRGAKSSGKSVLLGRLRGNAGSK
GLELGKQVSESSGKLKVACSLNQKEIADSMLSRGKREEERDEREESKEEWALGTFAFDDK
RRRGSASCPSLGGHENQETENSVTTDHAFEERDLLGLNCAPLKDASCRIGPPCTRSSFLP
SSEAQMAIGQVWDFDMLSFAALSPNPLVEVGLVLLLPEIDSLHCCTDQEVIVLLQNLQVS
>A0A1V4IPF7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium oryzae|TrEMBL
MRKQKFFVTLLITFIFIFNITVNGYAATLNVCDQYVSTDDKPVLLITEVVPYSTNDKYEF
VEVYNNSDKDINLKDYRLNYRYPYDGRSSDIPWTTDKTDIVIKAGNVMVFWIINSKNASK
TVADFNNNYSTNLVEGSNIVKIYGTGLANTGYRGVAITTNTGVDIDSAVYHKKNIAMNKG
IMYKCPVSGTVQSIMGGGKKAATPGQVLPSQIPYGSVYIGEDNVPPVIEYSSQTESIDST
KDYDMTVKISDDNQVKSAFLYYKFNATDDYQKVNLVLDKDNLYTYKFITPDLLGKKSIQY
YFVAGDGTNEVKSDVYESSIVGSNQYLWLNVKDDQYVSKSMELKASSNSYEAFATDMYVD
GKQQFDIYDALEDKAYFSFEVNRTTSEYKNGVVMNDKVIKALNSKISNYTTITVPVSSSE
LKIGEDNTISIRAGSRLGIFDDDDDNNKDDFYIRNVRLTLPNGYQIRPEQSEYNDPSKII
AVGDDTKLKASVQVNFRFNIDKSIVYTRACKIDTRKMSDGTHAVEAYLNNNTVTKKIIVD
NTPPAVEPLINTKKDYKGKIKIDFNVYDGGAGIDNYSVKFDNNPITLPYKTSSSLLTSGR
HNICVIAKDKVGNSIKKNYSINVVNENPYPPKKVDSAEGKNGDVSIRVKDPTNDRMKVSF
YKAYKYSAASMAAFQGEADIEPPKEKAISGESQLNNEQLQQINAVDGNYVETDSASKFPY
QRFDISIDNDAEKNSIVEINWQGKSLMGRLVTLYAWNMKTSRWKPLASSVAADTDFKLSA
SVRLRNYLDNGKIHVLVQDKIYHNEKLNNDNNKFSFVWMSDTQYYSQYKPKVYDSITNWI
AQNKEAENIKYCIHTGDIVNNYDNINQWENASKSMSILDNAAVPYGILAGNHDVGDSKAD
YSNYDKYFGSDKFNGKDYYGGSYKNNKGHYDLISAGNNDFVILYMGWGIGDKEITWMNKV
LNKYQNRKAILCFHEYMLEDGKRSLIGDKIFNKVVVPNKNVITVLCGHNSNTLCNVDGID
DNNDGNIDRNVYQILCDYQSGQGGDGFITLLQFDTENNKINLKSYSPYLNKYNFYDPAKY
PEKDSISLDVNLQSENRLVATDSIEANVYTKNMITSFKNVKSGSIVKTNIKSASSNAVYY
YVVAEDKYGGRSQSEIFKE
>A0A650F2M8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Helicobacter sp|TrEMBL
MRVFHLSHTDLDGYGCQFIAKEFFEHIHFYNANYGKEVLVRLNTILDHITHTPESLLASK
FGKTPKHKNTSSEKFLILITDLNLTLNEAHHLHQRIEELKISGIDVDILLLDHHISGQEC
MQKYEWYNLDSSRCASKITFDTLSLQYPMRDSTRKLWIENLSQMINSVDIWLEDGYQFAF
GKVAMGVISTSNELNRFMFDEEHRDYKFKLIESMKEFLDTPHGEVHFDNAVYSIKKTALG
GNPQTQTMDSITSNIQVHLLSSKKQLCTIFYKDKRGFLSYSMGGISVLANLFLRQNPEYD
FYLDVNTKGNVSLRANGNCDVSLMSKELFNGGGHKNASGGKIDGFKESFAYADIKSQVQY
ILDKN
>A0A4W4HQE4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Electrophorus electricus|TrEMBL
MIRDIDESNVDYEQFKKNLEYTASLLESVEQSLDMEDQLQELRPDSVPKEVHNWLASTFM
QQARRPLRYPDYKPSFRSIVHAVQAGIFVERMFRKMSSTAMTDQPLAVVNCLREVDRWNF
DVFALDVGSSGHALKTLFTELMIRYELNSRFKVPISCLMSFLCELEQGYNKHNNPYHCQT
HAADVTQTLHCLLLRTGLVHWLTELEVLASLFAAAIHDNEHTGNTNSFHILTRSDLAITY
NDRSVQESHHLSSTFCILQNEQMNIFTNLSREEWVELRSLVIEMVLATDMSFHILQVKAM
KHSLQQQERVDKAKALSFLLHTADISHPAKPWVLHSRWSKALTDELFRQGDKEGELGLTI
SPLCDRNTAPVAQSQIGFIDFIVDPTFSLLMDMAEKIIIPLVQDNPEPPEPINRHRSSYL
LLLRENYLLKIIKYLVQQFIIKLQTSNTSGQQRYDGSPDHCKNLLSQFSMYSPPPXXXXX
XXXXXSLRRHGNRVITVDRRGRGMGNRSLGQPGPSIAV
>A0A0R2G3J7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactiplantibacillus plantarum|TrEMBL
MRPLQVIQISDLHLTPRGQVPAHGQQYDPWGKLANIIDDIRRLPTMPDLIVFTGDLIHDG
SADDYQRLHAIIHTMEAEFDCHVRVILGNHDRRAAFYEGYLPADPGPYYASRMRIGNNDF
YFLDSKVSGYEAGWLAPQQLQWLGKHLRQAPTKRAFLFLHHPLDGPTMTNMHYAILQNTP
ALLSVLRGHNLGGVFSGHVHFVSSYLIGDNILNVVAGSAAYAIDCHDPHHHYVHEGSSYQ
IITIDRGQVGVTTRQLLHGKAVIDELTIPDTKFVGRAPQGYESR
>T1FZK3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Helobdella robusta|TrEMBL
EAEEVLSEVETKNYPSEVRDWLTMTFTRSLSNVRKAEDRLHFRGVATAIRAGIVVDRLIY
RRMSSSVGIHVPPNVLLQMKDLDDWNFDVFKVNEIGEGHALKYVGYELFQKHDLINKFKI
STSALDNFLGKLEQGYSKYNNPYHNLVHGADVTQTTHFVISSTDFILWLSDLDVFAVLVS
ALIHDYEHTGTTNAFQVNTKSELAYLYNDRNVLENHHVSATFRLMKEETNNILMSLTKEE
FKEFRALVIEIVLATDMSFHFQQLKNMKNLLTTPENIDKPKALSLLVHCADISHPGKNWR
LHEKWTNLLVEEFFRQGDREAELDLPISPLCDRKNTIVAESQIGFIDFIVDPSFQVLGDM
LDKIVIPLKEQKQEYASDESKISTNVPSISSPWSSSSCAKFNEDIGWFCFSYLAIKL
>A0A291E5V2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cedecea neteri|TrEMBL
MRILQLTDIHLFSDTSSAAAIKNRASFDSVVSYIISHRDLLNVDGIVVSGDISHDGSVES
YRYFFSKMELLDIPYAYLLGNHDSAEHVLLAHQQHGGINNVDAFQLSDSQWRILFVNSVV
KGDDYGLISPQELNQLESQLSDSDRKTAVFLHHHLLPVGTPLVDECLLLNGHELLSVCRR
NGVRFIGSGHAHTLFQRKTGDILLSVSPAVCHQWENGATSVKIVENSGFSVISLADRPVI
KTFII
>V4ZU93|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii (strain ATCC 50861 / VEG)|TrEMBL
MWFYSYLRHPNDVPSLCTHIRSSNIFLRLGPQYYLPEDERKSLFVRTCHLLYYLASLLFL
TTLTTYTAIKIPSSPSTTTELLSQLFPFNSIDDCNERLSCKVDCVLYAFPDLNCAKDDGS
LLTFGGNSYSSLYFYHYPGKDVPLQKEARTAWERCYQIMRETTGRLQFLQQDRETVERTH
TCFAGCKTNGAVTFTQKLTDGTPVVFDSGTDWLQMAPAGSLPQDTRPACNPSEPPSLLCV
EPTDECQHVTLRYQVCIGDTAFCFDIVRILITIALGVVWNVVLDAFVVWAMSIDDSDPQN
LGRVASKCGLQIIATAIIVSSFFCLVASMTRILSMDANIARHGTLWTSFVLVIIIDQLFS
FLFSVLIWYAMLRRCGRQLPDESRFQYKIHPSPVLVKLKKATRKIVNYNGFEMFFTMLLG
WMVVDLTCRMILCQFFFDETAFLNQADRILEVVDFIILILFIVEICLRIAADGLKIYFSD
PINCIDFFLVFFGFGIRIVDFFIQINKGIGNVLFIMRLVRLYRLHRPPTGSLAIGKKEVF
TSRVERIIAVLNKALEIEELTTREKDSLKWLIQTISSGKLYEMGSEEKKKTDSHVQAWIS
IISTQSQSANQMADDMENILLERVKQMTKAGDAETDMPAVLQLEYGIDVSLDHAIEGYLA
NNLITWNFDVFRFHVIAGRAALPKLFVRCLHHQEVCSLFNLKIENMLRFAMELEKTSFST
TPFHNSIRSAEVLQAMHLFLAFFDTQIKGFFNSREILAALLAAVVWDYQHPGFSSAFLIK
TQHAIAIRYNDRNVLEHHHVAAAFSLMQKLGENDPLLAFPEDQYIALRKIIIQLSQSGSR
SNQTACLSLLKTKLQQAEFPRSITEDKNIILCNLMNAANYSFLGRPLQLYLQWSQKYMEE
LFMQGDRELELDMPITKNCDRHTTSEAVVQLGLIDGWAIPIYITLAQTVPKLNAIVVSHL
RRNRLHWLDEQQEEDKSKEKQTKVTPIKRYSKTKQGSTEATGNGELSKPEATTVEIADGT
AGVPELRASANPLSEVD
>A0A0N4VA99|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Enterobius vermicularis|TrEMBL
MDTLRLESKGWEENVPSTSASSPKLTFVEKAKLSAISHISGVQKIRSPFGGKIPEYGVEC
NKGITEHIKMLDEWGPDIFEINKLSRGHSLTAVTYTILKNRGLLKVFNIHSGPLINYLLV
LEHHYRDNPYHNQIHAADVTQSMNVLISSPALKGVFSDLEVLSAIFASAIHDVDHPGFTN
QYLINSRLKVCMRCNTPQLGYYMPNFAGFMDLSNSMLYIEGDKQIEKNSELAIMYNDESV
LEQHHLAVAFKLLQDGSCDFLTNLSKKQRKLLRKMTIDMVSVY
>A0A183I5N0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Onchocerca flexuosa|TrEMBL
MSEAFNCNSGIDYIFQATSFFLNCPNVAHYVQETHATAALIAAAVHDLDHPGRGNAFLIN
TKQPLALLYNDQSVLENHHIALAFQLTLQSTNNINIFAGLTREEFTTLRQATVEMVLATD
MSRHFEYLTKFQQVVSNLNDNEENENNVSLTICRMLIKCADIGNPTREWELCEKWAMRIV
EEYFDQLNMM
>B7Q7J2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ixodes scapularis|TrEMBL
HPESRLARMFNGSIPIVLDSLKQHYFIDRDGKMFRHVLNFLRTNTVAVPADFPELELLYE
EARYYDIPALTRQLEPLREQAQQRRRAASCLALNISPDMGERIVISGERALVEQVFPEIA
QALMDARSGVAWNQDTKHVIRFPLNGYCKLNSLQTITRLLNAGFRVMASNGGGVEGQQFS
EYLFVRRNLPF
>A0A1I7VY16|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Loa loa|TrEMBL
MACLCHDLDHRGKNNAYMKSMSSPLASIYSTSVMEHHHFNQTVIILQQVGHNILKSFSSE
EYKEILGIIKHCILATDLAVFSNNKMELEAILTDGTFNWENTDHRLLMEAILMTGCDLIA
ASKPWPVHTEAVKVIFEEFYEQGDEERRNGQEPIAMMDRKKANELPQMQVTFMKHICVPC
YELIVTVIPECQQLLDRCLYNMKKWQELADEQKKAELEED
>A0A517MNQ2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseimaritima multifibrata|TrEMBL
MPIHLAALTRRRVLQAAGASILLYGRHAAAAKAAEVDPDLIYLLNDTHIGEKHPTDSPVP
SHLRQVVTELVQRPVKPACVLINGDLALKDGQHGDYRHFAQLIRPLQEAGIDTHLTLGNH
DNREAFYEVMKTQRPDQPLVESRHISVVETAHANFFLLDSLQKTMVTQGTIGKQQLQWLT
AALDASQTKPAIIVTHHNPRLGGDPVHFPGGLVDSQELWNVVGPRKWVKAYIHGHIHDRT
YAQHQGIHILNMPATSYVGNPTQSTTGWTTARLSPDGIALTTHTTDAAHPWNDEMKTLTW
RSA
>A0A517MLE7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseimaritima multifibrata|TrEMBL
MSTSPYGTTNGRRAFVKDGVLLLTAMSLGNQALSAPLAKRESVKIGLITDLHYADKPPGG
SRHYRDTPAKLAQAGIEFQKEKPNFVVELGDLIDAASSVKTEQTYLRKINAEFSQVCPER
YYVLGNHCVDTLHKEEFLSEVEQPKSFYSFDRGGYHFVVLDSCFRSDGQPYGRKNFTWTD
ANIPAEELEWLTADLEANSKPTIVFAHQRLDVSNNHGVKNCPEVRKVLEKSGLVEAVFQG
HSHQNDLNEINGIHYCTMVAMVEGAGIDNNGFSLLNLNADGTIHLKGFHKQQAYDWK
>A0A1Y5T4R2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseovarius litorisediminis|TrEMBL
MARILQITDPHVIAPPGLVSGQLNTPALMAAAIDSILADMEKYGVIDAVLVTGDVTDDGA
LESFDWFRTQIERLELPYFLIPGNHDRRDLMRASFADQAFMPETGHINWVHDLPDLRLVG
LDTLIPGQGSGILDQTTLEFLSEALRGRPDAPFLIAMHHPPFASGIRFMDELGLAGIEDL
QRILHSAPNTCRIICGHVHSMIVSTVGPATAIACPSISSHFKTDLRNDAPVGFMSGPTGY
MLHDWNDGFCSTGIPLSKAQGPFPF
>A0A2X4ZB01|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella oxytoca|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLDAIHASQRECDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
HWQILLMDSQVFGVPARRAERFPAGVA
>M9W6G9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Arthrobacter sp. CGMCC 3584|TrEMBL
MEHIEAEHPRPRHFLLHLSDPHLMGGPDPLYGVVDSEARLIQLFEEVKASGARPEAVIFT
GDLADKGDPEAYVKLRAIVDPACEELGAKVIWAMGNHDNRANFRTGLLDEPADDGPVDKS
YFINGLRVITMDTTVPGYHHGELSTSQLEWLTRQLDTPAPDGTILALHHPPVPSVLDLSV
LVELRDQASLEAVVRNSDVRTILAGHLHYSTTASFAGIPVSVASASCYTQDLNVPIGGTR
GQDGGQSFNLVHVYEHTIVHSVVPMGRSTTVGEYVSPEETKRRLDAAGVRIPESAKQRSS
AKLGLPTSR
>A0A1A6B3X2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium ragsdalei P11|TrEMBL
MEHDSKGKIKTHSQREVSSVSKKEGIILDLSDLHYTTDIDEKNEAYLLISDLKKVYFDNP
ESSIKLTDIDYVVISGDFVERGDSESSFEKAFKFIDILSKELNVPYQKIVIVPGNHDLSW
SVTMSSYHLTIGTPGPNDKVVTNVGTDLFYLKRNDAEWYKKFTNYSRYLYEMLYKVPFPD
NPKEQLKVILGDFIDNEKVAFFMLNTAAEIDQFNREVTYFDTDGLIKVSRQLPQDNIIKI
AVGHHPVDLTNSYGNDIPFANALQNENFKIYLHGHVHRSISLDYLNPQNINPNMVMIGAG
ALSVGKSGLWPGVPERYNVIKISKTDKPDKILVSVNTRQREYIGSYWQPAYIYYKDDGKK
LTNIWRNVI
>A0A1R4FMA4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Agrococcus casei LMG 22410|TrEMBL
MSFGKHPAPLTTLAHFTDTHLLAGGGLLGRSIDTDARLVESLDRLRETVRGQEAPLAALI
VSGDITDLAEPEAYARALQLLDTAADELGAQLIVTPGNHDERPPMAEHLLGLEASEAPLD
AVHDLGGLRVISLDSTLPGYHHGGFDQGQAEWLREQLRMPAPLGTVIVMHHPPVPYRTDV
MRLLEFVDDDELADIVRDTDVRLILAGHLHVVGGGTCGGVPVSVAGAISYVDDLTVSPES
MRGIDDAQAFSLVEVYAETITHWSVQSRAYEGTSPLPSSLLAKLASMPDDERREAFSRKS
PA
>A0A8C7GUN7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oncorhynchus kisutch|TrEMBL
FLIILLCYDRNQVLVKTVEAVCSKWDSLSRLRCMVKQLEEKDVNFEDLKKNLDYTASLLE
AVYIDGTRPGLDAEDDLQKLHSDGVPTEVTDWLASTFTQRARRPARRSDDKPKFRSIVHA
VQAGIFVERMFRRAYTAAMPDQPAAVVNCLRDIDRWNFDVFALNTVCHDHALQTLFLELV
TRYGLNSRFKIPISCLMSFLEKLEKGYSKHNNPYHSSVHAADVTQTLHCLLLRTGLVHWL
TELEVLASLFAAAIHDYEHTGTTNNFHIHTKSDFAMIYNDRSVQESHHISAAFRLLQDDQ
SNIFMNLSREEWMELRALVIEMVLATDMSSHLVQVKAIKGCLQQHEGLDKPKALSLLLHT
ADISHPSKPWGLHSRWTKALMEEFFRQGDREAELGLPFSPLCDRNSTLVAESQIGH
>A0A518FXK5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia panareensis|TrEMBL
MSSIPPDSRISLGRRAFLQHGALLLTGISATPLSRLAAAAEAKQRGAVRIGLVTDLHYAD
KPPAGSRHYRETLAKLKEAKAQFEKDQPDFVVFHGDLIDSGKSLTQEKKHLETIVKAISA
MPFPKNYVLGNHCVDQLTKAEFLQGVGQKESYFSFDRGGYHFIVLDSCFKSDGTPYGRHN
FKWTDANVPAPELKWLQADLKQIDLPTIIFAHQPLDLKDTDAHAVKNSSEVRKILEASGK
VTAVFQGHSHRNKYSEIDGIHYCTMVAMVEGSGLDNNGYSTLDVYPDGSLVLNGFRKQKD
YHWS
>A0A2G8Y754|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii COUG|TrEMBL
FICRPLFGSLAQMFPAQLGDRAAELRKNRNKWKSIIDGHERR
>A0A5P2ZS02|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodobacteraceae bacterium|TrEMBL
MLIAHLSDPHLRAKGQLYQGLVDTNALFDLALDALLALDPQPDIVILTGDLVDEPTAEDY
AQATAKLSRIRQPVYAIPGNHDEREAFRGCLSGAGYLPDDGPLHYVVDGALRVVALDVTV
PGEHHGQVDAAAASWLDRTLAQAPDVPTLVMMHQPPILSGIDCIDTYNCRGADLLEAVLS
RHGQVERLLCGHVHRYMQARFGGTMVITAPSTATSIALRLGPDAAPASVLEPPALLLHDL
RPGRPLMTHHVPIGRFPGPFPFF
>A0A086M9Z2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii RUB|TrEMBL
MHRLLDWDFHVLALPPASAVLVTRDLLTQFALKANMDIPGEILMAFSVAIYKNYRPNPYH
NFYHALNVTQVLCLLLALPDVAAQFSPIDYLVLSVAALGHDLGHPGANNLFMTRFDCWPS
RIYQNVSVLENYHAASLFQILRHPAFNVFCSVSPTNFAPIRKRIISAILWTDMAKHFDVV
AKLQAKIQGEMVLAEGIIVTLTKPYLEGLLLHAADISNPMMDFELCRDWAFRACDEFYQQ
NKMEEMGGFPPSMPSFEHFDEYNVAKCQVGFIDAICKPLFNSLALMFPAQLGDRATQLQK
NRCVPVIIFPT
>A0A2P9EVP2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces sp. MA5143a|TrEMBL
MLVLAHISDLHLDGTDRATRRAERVRDLLWGLPGRVDALLVTGDIADHGTEAEYEEAARL
LGLRDGDAPFPVLTCPGNHDSRGPYRKALLGEPPADGPVNSVRLFDDAAVLMCDSSVPGR
DEGELDAQTYAWIEETLDDLDGDRPALLAFHHPPVALHHPLPDAYRLGRPSALARLLERR
TEIAGIVTGHAHTPAATVFAGRPLVVGPGVTWTLRLPWEGDPVADREAPPGLAFHVLDDE
GRLTSHFRVAP
>A0A378Y9A8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nocardia otitidiscaviarum|TrEMBL
MYITRVAEYPRPDHVLFHFSDTHLIAADTALYGTVDAERRLSQLLAQAEASGITPTAIVF
TGDLTDHGEPGAYTKLRNLVEPFAERVGAPLVWVAGNHDDRTALRENLLDEPGSTAPYDR
VHMFDGLRVVVLDTTVPGHHYGEITPAQLEWLRTVLSEPAPFGTVLAMHHPPVPCVIDLA
VTVELRDQRRLADVLDGTDVRAILAGHLHFSTSATFAGIPVSVASATCYSQDLAVAQGGI
RGRDGAQAFNYVHIYPDTVVHSVVPIGSGPTVGEPATPEQAARKLADAGIVIPPAAGIPH
VVQRPATTPENDGESVS
>A0A1X1FH13|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lentilactobacillus parabuchneri|TrEMBL
MFDYKICQISDTHLTPKNARPANNQRVDPLLKLMQVFDDIYTTRVNPDLIVITGDLIHEG
SANDYRDFKTVIDQEERRFNVPIRVILGNHDRTRPFYQGYLQKSYLTRYYYSISNNEWDF
YFLDTKCGDLEQGYIDERQMEWLRAELHSSPKPAILFMHHPLLGAPLEQMKYSILQNGKE
LRRVIEDTNVKAIFSGHVHYANLFLENGILNVTADSTAYHINCANPHRHFITDGTSYNII
SLTDQQIGVETRSLLLGTDTIKAFDVADTGFVDRSILYNEMNRVLN
>J2Y4L0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas fluorescens Q2-87|TrEMBL
MPNESILTTADAALLVQLSDSHLFAEADGSLLGMNTRDSLRSVIDLVLNQQPNIDLILAT
GDLSQDGTLESYQAFRQMSGRIDAPARWIPGNHDEPQVMLEAAVKSTLLEPVVDIGNWRI
TLLDSAVPGSVPGFLAEEQLILLANALSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEVDQVRGGVRLLASPSTCIQFEPGSEDFAVGSQAPGYR
WLRLWPDGRLETGVERVVGFAFTPDYESDGY
>A0A0E1CKU2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae 30660/NJST258_1|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFID
SSHAGTSKGWLTDETISWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A2X0WVA9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Anaerobiospirillum thomasii|TrEMBL
MDKMTKEQVLQTKCDTGQISILQLTDMHLFASENGKLLGVRTADSFKAVIETIVNQHMPY
DCIFVTGDLSQDYSAESYQRFASLVKLLNAPVFFVPGNHDDGPLMYSIMGNLGINTSRYL
RIGTWQFIFLNSEVYAVPHGWVDRSEIDFMLTYALNNPDLNTAVCVHHLPHLVGSRWLDT
QTMHNQDEFISALHLIPKLRLVLSGHVHQEYDKTVDNIRYIASPSTSIQFEPFSHDFALD
MRGPGWRYLTLEPNGDISTKVFRLPSGRFVPDLGVGGY
>A0A0M2H609|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium trichothecenolyticum|TrEMBL
MRTAEYPDPERVLLHLSDTHLRAPSTPRLFDSVDGARRLAQTIGAIDASGIRPDAIIVTG
DLADLGEPGAYAALRALVEPFAERIGARVLWVMGNHDERGAFRAGLYGEASDARPVDRVD
ELDGLRVITLDTSVPGHHHGELREEQLAWLADVLATPAPLGTILAMHHPPVPSVLPLAAS
VELHDQRRLAAVLRGTDVRAIIAGHLHYSTFATFAGIPVSVASSTCYSQDLTVPVGGTRP
QDGAQALNLVHVYDDTVVHSVVPVEAPRALEHIDADEARRRLREAGVVPLSAARKDAPTE
PIAVLR
>A0A0D2LXJ3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Monoraphidium neglectum|TrEMBL
MEALAMADSAASAGIRAASAPSHAADVPALADDLELHSDYVAKSLLRAIQLINRLTLELN
VHEAMRSVRQVALELLECERVTLFLVLRSKRELRGRMGDEAADEVISVRFGEGIAGRVAL
TGGLLNVRDAYSHPLFHPGVDAKTGFRTRNILACAVKHDDCDSEPIAVLQARRGVGAAGA
LNKRGGADFSAVDEQHLKLFSVHLGNTLAKIRFYEEAKREKERMAALSQCFKKLAKASSL
DCALGTITEAVQELVHAERVVVFLMDHARGVLWSSFVHPVTGHVRQIRTKQHAGCVGRCA
TSKQQLCLDLREDPGPRDDPVLRQLLAAIEDSRVSSALLQPVLDPSTDGCMAVLVALNKV
GDDVADGAFEDGTFTRSDRYL
>A0A0D2LS16|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Monoraphidium neglectum|TrEMBL
MSGHGREAHWGTPITPAVPLSVEGLALDLRPHRRSAEQRRPETARTTGAAALHANDPLFA
KTPEHVEQPARPKGCLGKGQQMLQEHCRNVRDRPAFMLLPPLLTFLLLASASVAGVVLGA
DKFEADTRGRAESAALDWAASFRLSAEKIFTPLVTLSILIQQNPQFPALRAKFPSIAEEL
LHSVNQERSIIQELQLSPMGVISSIHPKNNNTDSRLGINIFKQPALRGGALDTVVANQIV
INGPLKLVQGNFGTIARIPIFISNATANETWGVAAVAPVDCPVSLCFNATTRERFWGFAT
AVGPLDDLRAGNDTRLDLLKQKGYKWL
>E3HQN2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Achromobacter xylosoxidans (strain A8)|TrEMBL
MARIHSLTRRDDAPAMLVQLTDSHLFGEPETSMLGVNTDASLRAVLRQIEADGKHPDLLL
ATGDMSQDGEAAAYRRLARVLSEAPALAQASIRCLPGNHDLPAVMRQELPQWSAPVTDVG
AWRVVALDTTVPGSNAGHLPASQLDLLEAALAETPGRHTLLAMHHNPMQIDSHWHDSMMI
DNPQALFKLLTRWPQVRVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNMA
PGYRWIKLYQDGSMATGVRRVQDALWHGAKAAADNAQAA
>A0A0M3HXR6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ascaris lumbricoides|TrEMBL
MISRKNLFPSYHCLYFTHKISFLAHFFQATSYFLDSPAVANHVQDTHATAALIAAAVHDL
DHPGRGNAFLINTRQSLALLYNDQSVLENHHVALAFQLTLQQSNNVNIFARLSRDEFVAI
RQAVVDMVLATDMCRHFEYLTKFQQTITNLHECDEERDTTSMTICRMLIKCADIGNPTRE
WSLCQKWAMRIVEEYFDQTSEEREKGLPLTMELFDRNTCNVPLTQCGFIDMFARETFTSW
SEFAELPELLQQLEVNYENWRQQTSTWNPAKNVNLMADT
>A0A4W6D4R8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lates calcarifer|TrEMBL
SVPSEVRDWLASTFTRQRSLILRRNEDKPRFRSIVHAVQAGIFVERMYRRTSNMTGFSYP
PNVITVLKHVDMWSFDVFALNDASGDHVCQQTVGYSKYKNPYHNLMHAADVTQTIHYFLL
KTGIVVSLLPSHDFEHTGTPITFIFRPDTAMLYNDRAVLENHHVSAAYRLLQNDDEMNIL
SNLSKDDWRELRTLVVEMVLATDMSCHFQQIKAMKGLLQQPEAIDKPKALSLLLHTADIS
HPAKQEFFRQGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEPTFTVLTEMIEKIVT
PLIEEASRSGLTGFRHSSINSISGSDGKHSSVKSTGSDGSCSLTTVDFKSFKVTWNQEIH
HNRELWKAQAAKDVKIRKEGEEDGQKKKETEEEKKPRTVDGANTGQEEAGDRPQQEEQQP
KKGEGDKNPGRAVGSLQGSDPNDADKRKPESHTDKQQRQSQNGMHSVNCFT
>A0A4W6DQ34|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lates calcarifer|TrEMBL
AECHVSIWRKQIFMLWLCGQMDRGVVDLQELRRNLELAAAMLDAVYTDETRRLLDTEDEL
SDLQAESVPSEVRDWLACTFSRKMGVAKRRPEEKPRFRSIVHAVQAGIFVERMYRRTSNM
AGLTYPPTALTALKEVDQWSFDVFSFHEATGDHALKFLVYDLLTRYDLINRFRIPVQALV
QFVEALENGYSKHRNPYHNLIHAADVTQTAHFLMLHTGLMHWLSELEILAMVFAAAIHDF
EHTGTTNNFHIHTRSEVAILYNDRSVLENHHVSAAYRLMAEEDMNILVNLNKDDWRELRS
LVIEMVMSTDMSCHFQQIKTMRNALTQTHGIDKVKVLSLMLHAADISHPAKAWPLHYRWT
HSLMEEFFRQVLCCSGIHEAVFRAVILRLTSSTLLTGEDVYDMQI
>A0A1R4H7V1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Crenothrix polyspora|TrEMBL
MKRNYTTVLQLTDLHLFAQSDVHFNKVNTRDSFIKVLNHVQQHYDNPDIIIITGDLAHDD
EPATYQFIAEALKVFNAPVYCVLGNHDHHENAYRVYPLTPVSTDLHCLLRRWQIILVDSN
HQPMPDSYQGEVSQAELQRVGELIAQHPDKWALIAMHHNLPHHDDRGVMLEVRNHEQVMA
YFEQQPNIKLVLSGHVHQEFVIVQNGVCYLSTPATGYQSTSKSGQVTGEAPGYRWLKLYD
NGRFETDVRRVTYWVS
>T1A5Q3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|mine drainage metagenome|TrEMBL
MRERVQLHEAISRVVDPMDTMQRVANEAMSAIEAAQGVVVGLAVGDTNVHFVCGAGYLEG
QAGSVIAREGSLSGLAMSEGVALRCDDATGDPRVNKVLSDAYGIMSSVAVPLRRGGQAVG
VLNVNSKRRCAFDDEDVRVLTRLAGFVTVL
>A0A1R4HAX9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Crenothrix polyspora|TrEMBL
MTQGYTTVLQLTDLHLFAEQHGVFNGVNTRNSYNQVLNHVRQHYSTPDVIVITGDLAHDN
ACETYQYIADSLKVFNAPVYCVLGNHDHSKNAYRVYPLAPVTTDLHCVFGQWQIVLLDSN
HQPEAGSYQGEVSAVELQRVGALLSRYPKLWTLIAMHHNLPQHDDRGVAIEVRNHQQVMA
YFEQQPNIKVVLSGHVHQEFVIVQNGVCYLSTPATGYQSTSRSGQVTGEAPGYRWLKLYD
NGRFETDVRRVAYWVS
>A0A1Q2MFT6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Limihaloglobus sulfuriphilus|TrEMBL
MSDNRHFHRTFSLLIVLTAMFLNGCCYQQVSCDTPPANESIYFVQITDTHLGVDDPGDLE
DHYGATEMIIGDVKELPVDVDFVAVTGDIMHEKTGDADAEEKTLAMFAKLEPPVHFLPGN
HDILYGPDSEELLDKYESAFGRADYGFENGGVWFIMFNSELLAEGTAEVIDKQIGVLKRL
IRASKGKRTVIFIHSSPAADLYGGKFHYGWPKEAAEKFTAAINSPQANVIAVIGGHFHRE
EKHYFGDVPVYLTGAVANFWGRQSVFKLFHIDPKGRITYRLRYLGRGN
>A0A238KMY3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Maliponia aquimaris|TrEMBL
MRFAQVSDLHLCRHPDRIEALRDDTPAIVAALARDLRRIAGILDCVIVAGDLTDDAHDES
FAQFEEMFAGIGVPVFTIPGNHDGPAAYHDRKTRSAFLRGADIAGRIVQVGGVRLLGIDT
CLEGMTTGAVSEQALDTVAGALDAPQDGPLVIVMHHPPFVPGQRVYDEISVIEGAARFAA
LLEGAAHKPTILCGHIHRPYTALVHGTLCLAAGTPVAPFAAPLPFGDGDIAPSDEAYAYL
VHQVGADGAHVLTTRSVPPGASGARDAG
>A0A081FY11|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Marinobacterium sp. AK27|TrEMBL
MSQQFIVAQISDLHIKAGGRLSYRKVDTLKGLYNALERLNALVPQPDVVVITGDLVDFGR
ADEYACLKEALSELDMPYYLVPGNHDNRQAMRAAFPELDHLHQQPEFVQWCIEDYPVRMI
GLDSTVPGAPHGELCAERLAWLESTLSQRPNVPTLVMLHHPPFASGIGHMDRQRLMDSAG
LAAVISRHPQVERVLCGHLHRSIQQRFAGSLACCCPGTAHQVVLDIDPDAPAHFVLEPPG
YLLHVWTPEQAMITHMGMIEHFDGPYPFFDSHGLID
>A0A0G3GT58|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Corynebacterium epidermidicanis|TrEMBL
MYTFSDSERGLPDHFFIHISDTHFAVEKGEKLHGVAAYREHLSKLLEAVEAMEVRPEALI
FSGDLTDFGTPESYLALRELVEPVAQRIGAQILWAMGNHDDRSNFRSILLRTDPHSASCD
SVYNFGGLRVVVADSTVPGHHHGEFSTAQLTWLAEVLREPAPEGTLLVMHHPPVPCIQEA
AISVELRGQHELSELLAGTDVRAILAGHLHYSTFATFAGIPVSVATSSCYTQDLFTPMHG
TRGRDEFQGLNFVHVYPDTVMHTCVPMPGGETVGRLIPGRPI
>A0A0J9Y1Y6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Brugia malayi|TrEMBL
DVELTFSLHLQIAPEDLLRLTAGDIPSATSFAPEFDHFNFSPRSIGDASHQTKTSFQDLG
FVQRFRLQRQTLACFLLMVQKGYRDVPYHNWSHAFAVAHFTYLLLRTETAHNALNELESF
ALFVASLCHDIDHRGTTNAFQVQSRTPLAQLYSSEGSVLERHHFAQTISILNMEECNIFA
WTIHCINLANLPFALSRMISTLCMECVYPIITTVISIFIYYRITKISVGFDSSIKHHRYL
LLCLMMTSADLSDQTKDFRNSKAIAENIYKEFFSQGDLEKQMGNRPLEMMDRDRACVPKL
QLEFMDTIAVPVFEQLLPESKNTYESMLFNRKCWLALDEILAEEKYPTLGLDYLKDTFLE
KRVIKFFVSFQSSNANVSSKTDYDYDGLTDFKQRNILCNGCMINIILW
>A0A142WXD4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Planctomyces sp. SH-PL14|TrEMBL
MPVHLSPIRRREFLQQSAAALAGFAVLRSASAAEGANPNLLALLSDTHIPENADVLAREV
NMTANLRKVVRDLVALKEKPAGVLVNGDCAYLKGKPDDYANFAGCVAPLVEAGLPLHLTM
GNHDNREALYEKLAAQKPAAPLVQAKHVSVLECPHANWFLLDSLFVTDVVTGQLGDEQRG
WLAKALDERKDKPAIVMAHHTPQFEPPPEGTKWGGIEDTAALFELLMPRRHVKAFVYGHS
HNWSVTMRDDLHLVNLPPVAYVFAAGKPNGWVSAAMRPDGLDLQLHTLDPAHRQAGEKFS
LTWRA
>A0A161THE7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Triatoma infestans|TrEMBL
KMGRSFNGRIFQQGDKEREAHMDISPMCDRHSATIEKSQVGFIDYIVHPLWETWADLVHP
DAQDILDMLEQNRDWYQSMIPPSPPPADTQPSSDQEESATAQDRTHDDIRFQVTLEEGES
EEP
>A0A136KUX9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chloroflexi bacterium OLB15|TrEMBL
MTQPEQFSTIAFRREDIQQMIQARPNDVLVRFVHFSDTHISADPNYSHAEADYIPMYGAK
EVVRQINALPFQPDFVVHGGDVVYDPDDTAYVAAREILSEIRYPVHYLMGNHDERNGFQR
ILLGQPETSPKHFYQFEVNGVQFLVLDSNAPAPFAGGSLGKIQLEWVREICAAPDDRPIA
VFVHHNAVPIGAPFWDDFMRMVDGEQFHAALLPAANRLRGVFFGHVHQSTETYRDGILYS
SVPSTWYQLHCYPGQSGILQDEGSDPGFNVITISSNQTFIRRHRFHVPEHGTNPIPKPGT
>A0A7Z6TAN0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces sp. CBMAI 2042|TrEMBL
MLLAQISDLHLDGSERATRRATRVMEYLRALPRPVDALLVTGDIADHATEAEYEEAARIL
TAPFPVLACPGNHDARPAYRKAFLGEPPAATPVNRVHHIAGTAILMCDSTIPGRDEGRLD
KETLGWIDSTLGALPDGVPALIAFHQPPVELHHPLPDAGRLEEPERLAALLDAHPRVVAV
LTGHAHTAAASTFAGRPLIVGPAVTWTLRMPWEGDRPADRDQPPGLAFHVLGEDRRLTTH
FRVVL
>A0A2T6J0H7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii TgCATBr9|TrEMBL
MAAHSPYLGRPGTFSAPDECWNEERVPSGISPADTIREIVLFQALRNAERWSARAHVLET
KTGKTPAVSVSGFGSADASEGQRAIGSKRATPGKEDSTKSSKDSPRSAFASSPPHAHGPG
ASTPPGPQSVCGASFWTQRRLLVRHKTYSPARFGISAEDERDEGEDRLSRDEGETGALAG
SPGFALGKRDRMRERKLKPPRRRSWMTVTENRKRREQEEQRRDDRSRVKENVLRGILKRE
KEEKKSNEGTRDGVRSSTCRHANPEHRTNREDRKGKTSGNHEMDENADRSRMSGTRKPGN
ETWGREKDLEDHQPHTCEMLPQENEITDIAEETERGRAVESAGTLSQKQARETKKREASK
EKGKGARRHAGESMQTSQMSLETELLHVEKRVCETV
>A0A4V0GPT1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Enterococcus casseliflavus|TrEMBL
MNVLHISDIHFRESYLPCEEGYQGMLAAMQNPLIPLEECIQDAKARGAIDLVVISGDLTE
DGAPADYASLKHYLEKAFGSVPIVVTLGNHDIKRHFRQGWQGKSVETASDTPFNQVYETE
TLAVVTFDNSCYGYADGIVDERQFEWLQATLAQLKEKKIIFVTHHHLLPYQASTPAWAGA
NRLVALLQQYQISCILSGHTHHAFTGTIAGIPYYTVASMSFVGEDEGEGMVRFEERYGYN
LYRFEEGALVHQSSENYRPNRVLMRVNMQG
>A0A150HFZ7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium laevaniformans|TrEMBL
MSHIASQHPAPEHFILHVSDTHFVGDGDLLHERIDSDKNLAELFDGFTKANARPEAIVFT
GDLADTGRPDAYERLRAIVEPAAEKLGAQVIWVMGNHDERVAFRRGLLDEEADQSEPVDR
VYDVNGLRIIALDSTVPGQHHGEISDEQLAWLRRELEVPAPDGTLIALHHPPVPSPIGLI
ALVELRDQERLAEVIRGTDVRGILGGHLHYSTTSTFAGVPVSVASATCYTQDLAVAYPGA
RGQDGGQSYNLVHVYGDRVLHSVVPIGQFPTVYEMTPEMLEAFMNMTPDEQLAAVNASAG
E
>A0A238LFS1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Flavimaricola marinus|TrEMBL
MSRVVVLTDLHIRAEPEPGKPDADARLLSAIDHINRYQSDADLVIVTGDLAHSGERAAYD
KLASHLTRLALPHVLMLGNHDNRAAFLDAFPQISPDENGHVQQVVDLPEARLICLDTLNG
PPYSYPFSHLGVLCAERLAWLDAALSGTDRPCILFMHHPAHKTGFAAMDAIMLMHGPAFY
DRILAHGNVAHIVCGHVHRTISGSHRGVPFSIFKSLVGQMPMLFDLMDFHMETDEPPAYG
LLMISDDGVVAHSEDFGLTDLDALRAASPQNASSQPK
>A0A239XWE5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chryseobacterium taklimakanense|TrEMBL
MDRIAFITDLHLLEKNVEKKGVDTLQNWKAVLDDVKAKNIGKIIFGGDFGEKEALEIIFA
DARDFEVELILGNHDRIKNFRKYYPKTEFKQELFYTLKIGGSDCVFLDTSSYRLNREQQE
NLKIWLESAVSPVIFIHHPVLDIVTWMDREHPLKNRKDVEEIINSAGKKVHLICGHYHQY
HEKSSEFINQIIAPAVSYQIPYGKNYQADTSSFGYLMLDWDDGILNYEKVDFNK
>G0M5B4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactiplantibacillus pentosus IG1|TrEMBL
MRGRIELRPLQVVQISDLHLTPRGQVPVHGQQYDPWAKLANIIEDIRQLPTSPDLIVFTG
DLIHDGSADDYQRLHAIVHTMEAEFDCHVRVILGNHDQRAAFYEGYLPADPGPYYASRMR
IGNNDFYFLDSKVSGYEAGWLAPAQLQWLGKHLRQAPTKRAFIFLHHPLDGPTLTNMHYA
ILQNTPALLSVLRGHNLGGVFSGHVHFATQYLIGDNILNVVAGSAAYAIDCHDPHQHYVY
EGSSYQIITIDRGQVGVTTRQLMHGTKVIDEFTIASTKFVEHTPKGYQSR
>A0A0F0CBQ6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium sp. FS41|TrEMBL
MRSKKWMIGIAMAAGISAAAAGCGREAAVEESARPSVSRTEEPSSEEQTQKPTSPQPSEI
EPFPGAEKETKAEPLKGGKRIVVMTDIHYLAQSLTDQGDMFRSMVEHGDGKLTNYVWEIT
DAAFEEIQLLNPDVLIISGDLTLQGEKKSHEELAEKLEQVENAGITVVVIPGNHDINNPS
AAVYSGSDRFPAEPTTPNDFVRIYDEYGYAEANSRDPNSLSYTYDLGPAMRLLMLDTCQY
EPRNRVGGMIKTETYEWIDRQLEDARDDGVILLPVAHHNLLEESKVYVDDCTIEHSEELI
QKLEGENIPLFLSGHLHVQHYMQNNDIGIYEIVTSSMSTPPCQYGVLEYMEDESFSYHTN
QVNIEKWARKHRSTDENLLNFNTYCPPTLNRIFYNQAYDAMKDSAEEETGSVYVKLTEPE
KQQMSKVYADINAACYAGKAYEVAGRTVKEPGYKMWQEYCYPSILYEYLEYIVEDAVKDY
NSLAVE
>A0A093RCJ7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Phalacrocorax carbo|TrEMBL
LFSRLRSLVKQLERGEASVVDLKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDSVP
SEVRDWLASTFTRQMGMMLKRTEEKPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYPPAV
IGVLKNVDKWSFDVFALNDASGDHALKFIFYELLTRYDLINRFKIPISALVSFVEALEVG
YSKHKNPYHNLMHAADVTQTVHYLLFKTGVVHWLTELEIFAMIFAAAIHDYEHTGTTNNF
HIQTRSDSAILYNDRSVLENHHVSAAYRLLQDDEEMNILSNLSKDDWR
>A0A177HI05|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces jeddahensis|TrEMBL
MRAKLTRRRVLAGSIGTAGAAGGLGLLAGSTGTAYGSRASAVPLARSATATVDGSLVAPF
GRHLAFGADPKTQMRISWQVPFAVRNPYVRVGLKPWELDRKIEAEVRDLNTPALSSKLPA
VDQYYLHAALDGLKPGTTYYYGVGHDGFDPASAERLSTLGSFRTAPATPETFVFTAFGDQ
GVSYDALANDQLILGQNPSFHLHAGDICYADSTGHGKDSDTYDARVWDQFLAQTESVAKS
VPWMVTTGNHDMEAWYSPNGYGGQSARWSLPENGFDPKSAPGVYSFVYGNVGVVALDAND
VSYEIPANKGYAEGRQTAWLDRRLGELRASSAVDFIVVFFHHCMYSTSTHASDGGVRDAW
LPLFTKHQVDLVINGHNHVYERTDAIKDGEVGRPVPVGASTDPTRDGIVYVTAGGAGKEL
YGFPVGVEDSYEGAEKDRDSILTFHWTKSRLPDPDTVEWSRVRYTGFSFLAVEAEAGASP
RLKVSALAESGRRIDYFEVARGKGQ
>A0A376KQ68|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli|TrEMBL
MRVSPPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHH
PLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQ
FKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>A0A377DLJ2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPETPYVAAAASSSATCGL
>A0A378B100|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae subsp. ozaenae|TrEMBL
MARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFIDS
SHAGTSKGWLTDETISWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLAL
VERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMHR
QVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A1P8YDK4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodococcus sp. MTM3W5.2|TrEMBL
MRTAEYPRPSHVLLHLSDTHLIDRPGALYGGVDSEARLRQIFAEIEASHARPDALVFTGD
LADKGEPGAYAKLRALVDPVADSLGAQVIWAMGNHDDRAHFRAVLFDEDSQTGPVDRTYD
IDGLRIVTLDSTVPGHHYGEIGEAQLRWLAAELATPAPHGTILALHHPPVPCVQDLAVLV
ELRDQTGLAEVLRGSDVRAILAGHLHYSTTATFAGIPVSVASATCYTQDLTVPPGAQRGR
DGAQGHNMVHVYPGTIVHSVVPMGGQDIVGEYVTAEETARRLDAARVRIADSERPVVPVR
ADRV
>A0A3S4XXP7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Actinobacillus equuli|TrEMBL
MAEVLSRYPNVKAILHGHIHQEVDADWKGYRVLATPSTCIQFKPNCDEFTLDLLPQGWRE
LSLFEDGRIETEVKRLNSNAFYRTFSPRAIKKKSVRK
>A0A1J5NT89|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moorella thermoacetica|TrEMBL
MFRVLHLADLHLGHRPDLPAPLQEEVCRERNGVLKAAVDLALDPRQEISMVLIAGDLFDH
HQPEAPLVEETIRELGRLEAAGIRVVTVPGNHDEITYNDAVYRREARRWPGLLVTEPMPA
KVATLNINGDACHLVAMAYTGGVSRVDGPLKDFPPAEGSGVTLAVFHGSLDWDGGERSLP
LDGEALAAAGYDYIALGHIHRGGQKHLGRSQACYAGMVAGRSFADPGTGSWTIVTLGDGP
ARVEQVPAQVTPWRVVEVDVTAFHEPEELEAAIRESLDPGALMQVRLVGTIAFELALEGL
QARLGHLCSYLELVNDTEGWAPEVLESLAAEPTIRGLFVRRLRAKLAGAAGPGEAELVRR
ALFRGLLALKGGGRSCRL
>A0A0C4YBU1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cupriavidus basilensis|TrEMBL
MNTTNDNPAGTYLLAHITDLHIKAGGKLSYRMVDTAGALRRCIASLLAAPQQPDSVVITG
DLVDFGTEEEYRFLRGILQTLPMPVRLLPGNHDHRATLRRVFADHDYLFANGDGDAPVHY
SVEAGPLRLVAFDCTVPGKPGGQVDPAALPWLEATLAAEPGRPTLLMLHHPPFHTGIGHM
DRQGLADAALLEAVVRRHPTVERVLCGHLHRHITHRFGGTIAMTAPGPAHQVTLDLDPQA
ASRFRMEPPGYLLHQWDPAHGLVSHAAVIGDFGADHPFFDAAGKLID
>A0A0D8FXV5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ferrimicrobium acidiphilum DSM 19497|TrEMBL
MTRIVHVSDLHFELAPERFKPGVRQELDLSIPAIRAARPDCLVVTGDLTSYGCFDRSQLV
GVRRWLDGIGVDYLAIPGNHDLSANVVRGSSYPIMETYEPVPWAATNFARTFSQEPLVHR
GEGPVTLLALALREDDPDGSLDLLAQALDRLEGPALVLGHYPLAVTKEVGVLASFGYQGY
IDRVRERMLELLHSQPLVRAYLCGHVHAQTVTPLGADLIQLSAGGLGPGASAGWIIDVVD
STLEIRSLRGGGSKVFWPAEMLDGNDALDYHLWCGQEPVVVPLYVA
>A0A0P1FWS6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thalassobius autumnalis|TrEMBL
MSKILVMTDLHLVVPPETIIDLSPAERLAEGLAHAAKMHPDADHLVLTGDLTNEGTPAQY
AVLQPLLADLPWPATMLMGNHDLREPFRASFPDAPVTEDGFVQAVIDLPDVRLITLDTLD
TEAEVLHSGVLCPARLNWLKAALEGAEGKPCLVFLHHPPFDTGFNGMDGIGLTNAPELLA
LTAEYNVRHLFAGHIHRTITATVAGQSMTVFKSTCHQMPMLLGQEGFGHSVPEPGAYGII
LTRGEDVIVHTEDFTLPEMENKDFEAH
>A0A517QS42|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thalassoglobus polymorphus|TrEMBL
MYAECVRSVMKNSNLKSIPMSTDSTQIQIGRRAFLQNGTLFLVTASTVGAAGTAKLYGAD
EKKLLRVGLVTDMHYADKSPRGSRHYRESLDKLSEAGAEFQKQPLDFLVELGDIIDAADS
VETELSYLKTINKEFSQIAKDRHYVLGNHCVDTLTKEEFLGSVEQEKSYYSFDKGGYHFI
VLDSCFRSDGTPYQRKNFKWTDPNVPKEELEWLAADLKQTRNRVIVFAHQRLDVSDNHGV
KNAPEVRQLLEESGKVDLVFQGHSHKNDHKEIGGIHYCTLVAMVEGSGEENSGYSVLELS
RESPIQIHGFRKQADYALK
>A0A0C1M9D1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Levilactobacillus brevis|TrEMBL
MGAWGMNRFTIVHISDIDLTMDDNQRLATQPLQRVFDDLEDHQVAADLIVLSGDLLIDGD
QQGYRQLHQYLQQQERRLQVTIQVLLGDRDDREAFNRGYLAVAHQSYYADKQVHQNMDFY
FLDSKWELNKSAGWLDRPQLDWLNKNLHLAPRRRAFIFLHHPLDAPALRDMRYTLLQNNR
ELLAILHGHNIGGIFTGHLHFDANYVVDSVVPVTVTGSAATYINCQDPYQHDVYTGTTYN
VITIQRGIASVITHPLALGQTVIQTIPVNRTGFVKHRPRAIPVRRPLP
>A0A3P8M187|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Raoultella terrigena|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWESYQAVLEAIHASQRQCDLIV
ATGDLAQDHSAAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQESGISPAKRVLLGD
RWQILLLDSQVFGVPHGELSDFQLEWLERKLAAEPERYTLLLLHHHPLASGLQLVGSA
>A0A2A6D3S0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pristionchus pacificus|TrEMBL
MAAEFSVNPEEIRRLSSLPIPPTSHFSPHFTSFHFIPRSIGGGDAYVEASIAIFNELGFI
NRYRIERKKLAGFVLRVAQGYRNVPYHNWSHAFAVAHFAFLLLRTPAVRGQLDELERLSL
VIACLCHDIDHRGTTNSFQKQARTPLAQLYSSEGSVLERHHYQQTTNILSEVECDILCNL
TGNQHKTVYDHIKEIILATDIAQHMTKVGEMRKMITQGINPSREQHHYLMVCLLMTASDL
SDQTKHFKNSKGIAESIYTEFFSQGDLEKQMGAAPVEMMDRDRACVPRVQIDFIDTVALP
VFDMLSSAVPESLPTFHSLLNNRRCWAYLEEIFKERGVTTNGLDFLTDQLLEDEVLSRAR
SHNCRSDIDEVLQSIDWTPLNPSKLDHL
>A0A498SRC5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acanthocheilonema viteae|TrEMBL
MPRGRKRSVVDAFKIKHKSDSFDGYRRISSDIRNALLNDTQWNFNILNLERISENHALSH
LGTKIFERWKIHETLKCSMDLITRWFDEIEVHYHAVNPYHNATHAADVLQATSFFLDCPT
VAHYVQETHATALLIAAAVHDLDHPGRGNAFLINTQQPLALLYNDQSVLENHHIALAFQL
TLQSTNNINIFAGLTREEFAALRQATVEMVLATDMSRHFEYLTKFQQVVSNLKDNEENEN
NVSLTICRMLIKCADIANPTREWELCEKWAMRIVEEYFDQ
>A0A833JNN3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Marinobacter nauticus|TrEMBL
MSKPTTARPLNVLQLTDPHLMASADGALLGVNTRDSLAAVIDEVLRNHGQPDLILATGDL
TQDASPEAYRYFAEQLQAFDCPSLWIAGNHDDSALLSSIAAESGSDQKQWIQGGWQFVML
DSSVHSKVYGELSADELSFLDRALSEQPEMPAVVSLHHHPVDIGSDWMEKIGLKNRDAFW
QVIDRHPQVRVVLWGHIHQELEQQRNGACLLATPSTCIQFATGSSDFAVEPLAPGYRWLE
LDPSGCFKTEVRRAASFEFDLDEKSTGY
>A0A0F0KFB2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium foliorum|TrEMBL
MSAHSESEHVFGRHQPASHVIIHVSDPHFLAEGARLGGRYDVESNFARTLEAVRAVHPDP
TAIVVTGDLADLGEPDAYRRLRAAVEPVAEELGTTVVWVAGNHDERPALREGLLGLEPTS
DPVTGVWDLDGLRLIALDTSVPGWHHGDLDEDQLSWLRDVLREPAPHGTLLAMHHPPLPS
HLPLFDILELRHQDELADAIRGSDVRGILAGHLHYSAHGMFAGVPVSVSSATCYTMNVAR
PAADVNGMDAAQAFQIVHVRADTITHTVVPVTDAPTADVFSQAWIERMAALTPDERLEVF
SRKR
>A0A7Z7LVN7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Elizabethkingia anophelis|TrEMBL
MKRRKFLAKVPLAASALMLGGTATNLLAATQKDKNINLKKKLLLTVAHITDVHLPADPKV
MERFVKCLKEVKTKKVDFFLNTGDSIMAVDRDNSTRQEVYDQWNAWDSCIKEIADYDMYS
CVGNHDIWWAGGKSDEMYGVPYAAKRLKMPNRYYSAKKGKWHFIMLDGNNSVVTLDPEQM
NWLKQELENIPQGEYALIMSHYPILTVTGTFEGGQHKDHVALKDLFYKHKDKVKGCLSGH
QHLLDRAWYNDVYYFCNGAMSGFWWGEGDKRSAKPFYYQETPPGYAILKFYDDGTFENEY
IVHHY
>A0A142CLB8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Shigella dysenteriae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYVVDDFATRLLFID
SSHAGTSKGWLTDETIGWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLE
LVERFPSLTRIFCGHNHSLTITQYLQALISTIPGTVHQVPYCHEDTRSYYDLSPASCLMH
RQVGEQWVSYQHSLAHHAGPWLYDENISCPTEER
>A0A1S8TFW8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium puniceum|TrEMBL
MRFLILSDSKGKENGINKKILIKLLNESCKLTPRADFIVLGGDNIAGSSIDNVLVDQLQT
LRDLIEKYYPGIPLIPVVGNHEVNNEPKDDNCERIFRRIYNDMLPNTYLDGYNKTVFYVD
YEDVRLIILNAFHFNEINKIEKRQLSWFKEVASADVKNKIVFVHSPAFPTGAHYGHCLDL
YPQNRDAFWRIVHDYNIDLVFSGHEHNYSRRKIQYEKSIYQVITGGSGETLRDKFKDKKG
IIIAPIAKYHFVVVDIIASGIEVSSISSKGKLLDKFKIDKDNAD
>A0A8C9ZMA3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sander lucioperca|TrEMBL
MYLMKNKSNEKPKFRSIVHAVQAGIFVERMFKRAYTAAMPDQPAAVVNCLRDVDRWSFDV
FALNSASSDHALRSLFFELITRYGLNSRFKIPILCLTEFLSALERGYCKHNNPYHSHVHA
ADVTQTLHCLLLRSGLVHWLTELEVMASLFAAAIHDYEHTGTTNNFHIHTKSEFALIYND
RSVQESHHLSAAFRLLQDDHMNIFTNLTREEWMELRSLVIEMVLSTDMSSHLLQVKGMKS
CLQQQERIDKPKALSLLLHTADISHPSKPWALHSRWTKALMEEFFRQGDREAELGLPFSP
LCDRKSTLVAESQIGFIDFIVYPTFSLLTDMAEKIVIPLVEENPGPPDPSPSCCN
>A0A0F2C2W3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium sp. SA39|TrEMBL
MSAGTGTAHAFGRHRPASHVLIHVSDPHFLAAGARLGGRYDVEANFARTLDAIRAVHPNP
SAVVITGDLADLGEPDAYRRLRAAVEPVAAELGAPVIWVAGNHDERPALRRDLLDLPPTE
EPVTGVWDLDGLRVIALDTSVPGWHHGDLDAGQLRWLEETLAQPAPHGTLLAMHHPPLPS
HVPLFDILELRHQDELAAVIRGTDVRGILAGHLHYSSHGMFAGVPVSVSSATCYTMNVSR
PAAEVNGMDAAQAFQLVHVHPDTITHSVVPVTDATTGDYFSEEWLERMAELTPEERLEAF
SRKPGR
>A0A8C9ZKQ3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sander lucioperca|TrEMBL
MCVVSLRQCLETEDDLQQLQSDGVPSEVTDWLASTFTQRIRRPVRRSDEKPKFRSIVHAV
QAGIFVERMFKRAYTAAMPDQPAAVVNCLRDVDRWSFDVFALNSASSDHALRSLFFELIT
RYGLNSRFKIPILCLTEFLSALERGYCKHNNPYHSHVHAADVTQTLHCLLLRSGLVHWLT
ELEVMASLFAAAIHDYEHTGTTNNFHIHTKSEFALIYNDRSVQESHHLSAAFRLLQDDHM
NIFTNLTREEWMELRSLVIEMVLSTDMSSHLLQVKGMKSCLQQQERIDKPKALSLLLHTA
DISHPSKPWALHSRWTKALMEEFFRQGDREAELGLPFSPLCDRKSTLVAESQIGFIDFIV
YPTFSLLTDMAEKIVIPLVEENPGPPDPCNRHSLFKAFEKEGSEKCSFG
>A0A060RV74|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Plasmodium reichenowi|TrEMBL
MMDTKVDQTIQPKFYGDKKLSKSFDNKLDEENFNYPFKKESFLKSEKFCFEHTKDSLWKC
IKDKAKKKSDMEYFNCVNNLCCKFICSIRKYVKYFLYLKDSSYEIYNIKLYNNNNMNIIN
NKNITNNINNSFSNDYINYNHNYNHLNNSSSSKHNNYNVNNIDEKNIKNDYNTYHNIYEQ
IFFKYNSSFYEYLMFMLMKKLIHYKNYIFNKTKKINNSYNNNDIKNIDGFLIFQNINFEE
IFLNTFYSSFPFKLFLYSLYMIFICFIYFVLLYFMLLKNIYTHPFIFHLSVLKFFFDIIF
FLSFILYPLFLRLKRIDKIIYSSYISSYIFVCITFLYSFIIFKCSSYSVKMNSNTYQNNF
VFQNMLFLLINIIYICIFCFLKNYMILYSFLYNCRFSIFCILFIFLYYYLFFSLDFYRII
HLPFDNFFFPFLCFLFFSFLFIFKIIMSLYYEYVYEKKYRILFVKKNNLIEKRITKRKNT
NINNVYFTKYFSIDNTIPTSPIEDILNNFKHILETIHVIEENPNHNLTTNIMKIKEKIKN
CDNILRTKNINQVQIGKYRKFEKVYNIWCLDKMYLNYPLNQEESKSFLSNSLNRISFNSF
SNMHSLLSSKFQEHYNDIYDWNGNIENIYKANTFISIGYKLLYPLGVLEANFDKEKLKKF
LFRMCSYYNDVPYHTSLHAAQVAHFSKSMLFMLDMNHKISAIDEFCLHISSLCHDTGHPG
LNNYFLINSENNLALTYNDNSVLENYHCSLLFKTLKNPNYNIFEHYPYHIFISCKKNIIK
AILSTDMKNHFEYISDFRTSKEFIDYDNLSNDQIWQIFCLILKASDIGHSTLEWNKHLEW
TLKINEEFYLQGLLEKSLNIQNSFLCDINTMNKLALSQIDFLKHLCIPLFNELNYICKNN
DVYTHCIQPIENNIERWESHKNDNQNLGLHEKYKEENLLSKLELIKFE
>A0A221W7B4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Actinoalloteichus hoggarensis|TrEMBL
MVLLAHLSDLHVDETDRAARRVRRVMDHLRSLPRPVDAVLVTGDVTERGTEAEYARAAEL
LHAAVPVLLCPGNHDERSAFRRFLLDGRAGRATCGDTGREQAHAATETVGPINQVHRIGH
SAIVLLDSTIPGSGEGVLTPETLDWLDTTLADLGRTTPVLLALHHPPVDLHHPLPDRYPL
RERGALARLLIRHPEIVGVLGGHAHTAAVSTFVDRPVLLAPAVTWTLRMPWEGDDPADRT
APPALAFHILDENARLTTHFRVVP
>A0A086PIE3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii VAND|TrEMBL
GDEEKRLGLPVSFLCDRDQHDREFFKSQVGFLDFVVKPLYEELKALETQLNLNPQLPIEN
ICMKNLQENISEWKKKNEERRASLEPAGLEVGGA
>A0A086PK02|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii VAND|TrEMBL
MHISCVKGRIVARQIDNVFTVIFAIEVLGKFVSYGLEYLQDPIESFDTIVVLTSFTLLVL
GFYVSGIGLLRILRLLSALALLHKYPDSKEKRPELSAGNSSKLEKASSIVEGLLTNVHIP
KYFKTELEWVWDSILANKVYDSHVVENEEEEEDQATETIIAGSDASRKTQAAVRASRAQS
RASKLPHGSSSMVVGTTNGRISGQILETLREPDPRMMDAALYKSETRNLDPLTATVGGMK
NSPSMFAKGSKSSNMMGSSASKSFRTERNKKAIDIISVLYQASQITGAEQEQVNEAMRPF
DEWQWDALHAGDVCDMNLLPVVFVRAIATFPTIMTKFNFDLDRLFDFLKVVQTSFQKNVK
FHCAAHTADMIQAMHYFLTIGKLGALLSEYDVFLCHFCALVCHFGHPGVTNTFLVKSRHP
RAIRYDDESVNENYVASAISCLVAREEYNFFGDKLPLWQVFRLHMIDILLNFDISKSAHQ
VAMFRTKVSIKFTASTPADKQLLLTILLRAADYSFTCRQLALYSKWKDRMIDEFFAMGDT
EKQLALTVSPFCDRELTNVDKCHVAFAEVAVKPLMTVLVLGLAPHLQKDVLDTLEANQKN
LMQKLDKSD
>A0A086QLD6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii VAND|TrEMBL
NMPVSPLCDRDKHADMAKSQGGFLEFVVKPLIKEIDEIDPFGRVRSDILSHIEYNEKKWQ
ELQESGTEVVLVSHTSAEAADRNTVTTYAVRKIAGISHQQSKTATSKPSAAFFAPDQGLR
SANSKMMLRTIGSMPDVIRKHLQEAQKEEGEGEEKAPAEAPALSQGASGGQVAPVASGAR
KDSRDSQTSRRGDSAEERVLPRPRRSHGSGASSLVGEKVKERVSFADSVVSLGRRGQRGA
STSTDGSGRLDTNLSLAFTASDSAAGLDSSRASDDNARRDKGELNATGSRTSTSSSGGRS
RELSLEEASHTDSGSSPRGLLSSSGLRVTFGDLSEEDDSEDADSDEYKSVKSERETSGAS
ESHQSPAGPSQGAPPRLFETAVTMKNPEHHASRKQ
>A0A517NZW2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Planctomycetes bacterium K23_9|TrEMBL
MNNNDEARQIGRRAFVRGSALVLGASSVLPQALLGDEARTSADDGHRLKVGMVTDLHYAD
KPTAGSRHYRETLAKLDQAAGQFLRDEPDFVVELGDLIDRADSVETEQRYLKTINKEFSA
ICKDRHYVLGNHCVDTLKKEEFLGTVGQQKSFYSFDRGDFHFVVLDSCFRSDGQPYGRKN
FKWTDANIPAAEIDWLQSDLKASNRKTIVFAHQRLDVSNNHGVKNCAEVRAALETSGNVL
AVFQGHSHKNDLKEISGIHYCTLVAMVEGAGVENSGHAMMTLGVDDSIVVDGFRKQSDYR
WATPAMAN
>A0A1R4GKJ0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Frigoribacterium sp. JB110|TrEMBL
MQFGMHQPAHRTLVHISDTHLLAGGARLHDRFAVEDNLRRALRRVEQTGISPDALVFTGD
LTDLGEPDAYARLRSIVEPFAAQLEAPIAWVAGNHDERPQMRRDLLDEEPSEKPIHHTWD
LDGLRLIALDSTVPGWHHGDLDEAQLEWLAAELAEPAPLGTILALHHPPLPSHVPMFDIL
ELRGQDRFADVLAGSDVRTVLAGHLHYSMHGTFAGIPVSVAAATCYTMDVAREPQRVNGM
DAGQAFNLVHVYDDTITHTVVPVDGADPAGAFSPEFYARLAAMTPDERLEAFSRKPGR
>A0A098FYU3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas xanthomarina|TrEMBL
MPGASLTVDDSVLLVQLTDSHLFAEADGKLLGMNTCDSLEQVVELAIDEQPRIDLILATG
DLSQDGSVASYQRFRRLAERIEAPARWCPGNHDELAAMREACRGSALMEPVLEIGGWRVV
MLDTLVAGSVFGMLRNDQLELLERALSEAPDHHHLICLHHHPVSIGSRWMDTIGLRNPDA
LFEVLDRHSNVRALLWGHIHQEFDSWRNDVRLLASPSTGVQFAPQSEDFQVDSVAPGYRW
LRLYADGQLETGVSRVSGIEFEIDYSVKGY
>A0A2N7RDM8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. AD21|TrEMBL
MSSGYPVRLAGEELWLLPEKALYWPAQQALLIADVHFGKAAAYRRLGQPVPQGTTATNIE
VLDHLLAKLPCRQLIFLGDFLHGPGSHAAGTLNALAEWRARHADLPMTLIRGNHDKRAGD
PPASLNIRVVSEPLLLGPFALQHEPIPHPERHVLAGHVHPVYRLNGRGRQSLRLACFRLG
ERLSLLPAFGAFTGGYPVQIDAHCRILVVGDNEIWPVS
>Q5E5E5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Aliivibrio fischeri (strain ATCC 700601 / ES114)|TrEMBL
MFKNKLAVLFTCLSVFSFSAQSGSFDTVTLGSKGGIQDGNLTAFLIKSEADSNFVMLDAG
SVVNGLIVSEQKGAFKDITVPDSSPYTKVGYLLKDKIKGYFISHAHLDHVAGLIISSPDD
SKKPIYGLAATNKDLMKNYFNWSAWPNFGNKGEGFKLNKYNYVDLQPGVWSPIAETTMSV
MSLPLSHSGGQSTVFILKDSEGDVFAYFGDTGPDEVEKSSAMKTAWSALAPFVKQGKLKG
IIIEVSFTNETPDKSLFGHLTPNWLVKELSVLEDMNGKGSLNDLNVAISHIKYSLKNSED
PKVIIKKQLAEANDLGVNFIFPEQGDSLQF
>A0A1I8A2U8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Steinernema glaseri|TrEMBL
MSRISGVRRLKTSHGASGNVPEYGVECAKEIAVYMQQLNDWGPNVFKIHELSKGHALTSI
AYSLLHQRGLLKTFEIPPHQLITYLLHLEHHYRENPYHNQIHAADVAQSMHVLISSPALK
DVFTDIEVLAAIMAGAMHDVDHPGFTNQYLINSNSELAIMYNDESVLEQHHLAVAFKLLQ
ESNCDFLSGLSKKQRQTFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVSGSHALELDK
YNDRIQVLQSMIHLADLSNPTKPIELYRCWNERICEEYWRQGDREKDLGLEISPMCDRTN
VTLEKSQVGFIDYIVHPIFETWADLVYPHAQNILDQLEENRNWYQARIPEETESARDEGV
VDGGATSKQEKNISADHLSEEDIENV
>A0A1V6EVV5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Hydrogenedentes bacterium ADurb.Bin101|TrEMBL
MWRFVHITDTHLSSTRNGVWNNRFLCSMMPEVMACLKRDLARLNPEFLLVTGDIVSNRSR
DAVFKARDLLESLGFPYYPAGGNHDFYSMESRAWFLEAYAHRLPSLNTVYTFEHKGLRFC
VLDPWWVWRDGALMPIAEQDIAEMQEEGLRDTRWALPPEQFVWLESILNAFPDQPTCIAS
HYPVVSPPEYFFQPEYNFAGALENGGLLADVLSKYPQVKAVFSGHIHTNAISRDNGILYV
ATSALPEYPVEFREVNVHADRIEIKTHGLGDPAFAERSRIRSREYTSGQESDRTSVIYFG
>A0A1B1NNW0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio scophthalmi|TrEMBL
MKSSSKKARKFSIRFTVGSMFLFATVLTAIFAISLQYYFSRQMTEEHVLSKLTMASSEIS
DYIQQIDVNATSSAQILRTVSTAAEKQFSEKEIRDIFVQVLKDNPLFYSLYYGNRAEDFY
QIINLESSPIVRERIDAVEQDRWVIIKIKGSGDERIRTTEYYTDSLKRTRIISQHSNYFP
SQRPWFHSATQSTVYKTDPYLFKHLKITGQTYSIRSKKSVIGVDIVLSSLSSKISSDAKG
IYGGDGVEAFLFNHNGEVIASNLAQNATMSIPNGVPMKLTDDQIRNVQYAPPLKVSNQNN
WGPYDFAQAGEPKGYSIDQLKLVSQMTGLQFEFVNGFTTQDLTHKFNQGELDIIHSLTDK
HPLNGSGKSVKMYTARLGVAMRQEGRLPTTVTELQQGVIAVIEGRGIEQVLHHLAPTLNI
KPVLRFEQAKALLLEGKVDFVIDSSFALNEIRGAANSDAITVGDLNDFNHVPFHLYASKE
HAHLLPLIEQAIKQFTPLQKRALELKWLDDSVSKAGFLPYPELFNLSLQQAQHNQMISAE
SGEQFLYVTPVSNSGAQEYFAVVVPTNVITKQVVERLVTSISITICAMLILLPIAWIFGS
PIVQPISQLRRETLRIKQRQFNQVRLVDTRIKEVHELSLSVVEMASEIERHQKEREAFID
AFICLIAQAIDDKSPYTAGHCNRVPELGMMLAKIAEDTDTGKYKDFRFNNDDERREFRIA
AWLHDCGKITTPEHVVDKGTKLEANYNRIHEVRTRFEVLWRDAEIEYLRSLLDESIDKGS
AFEKLHNRQSELKQDFEFVAKANVGGEFMSEDKIERVKSIAQQTWLRHFDNRLGLSPFEE
LSKVPPQGSLPVKENLLADKPEHIIHRVRQIEFEEKHGIQMEVPEHQYNYGEVYNLTISR
GTLTPEDRFKINEHMISGIKMLEALPFPPELSNVPRFASTHHETMDGRGYPRKLSGADLS
IPERILVIADIFEALTAADRPYKKAKPFSVAIDIMHKMALDKHIDEDLFLLFLTNGGFQQ
YAEQFLPATQIDYVDVAKYIKRPDFA
>A0A1V8ZHG0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Enterococcus casseliflavus|TrEMBL
MNVLHISDIHFRESYLPCEEGYQGMLAAMQNPLIPLEECIQDAKARGAIDLVVISGDLTE
DGAPADYASLKRYLEKAFGSVPFVVTLGNHDIKRHFRQGWQGKSVETASDTPFNQVYETE
TLAIVTFDNSCYGYADGIVDERQFEWLQATLAQLKEKKIAFVTHHHLLPYQASTPAWAGA
DRLVALLQQYQISCILSGHTHHAFTGTIAGIPYYTVASMSFVGEDEGDGMVRFEERYGYN
LYRFEEGALVHQSSENYRPNRVLMRVNMQG
>A0A0D6FHB4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Alcaligenes xylosoxydans xylosoxydans|TrEMBL
MVRVHSLARRNDAPAMLVQLTDCHLFGEPETVMLGVNTDASLRAVLRQIEADGKRPDLLL
ATGDLSQDGEPAAYRRLAAMLGAAPALDGARIRCLPGNHDLPSALRQELPEWSTPVTDVG
AWRVISLDTTVPGSNAGHLPDSQLDLLEAALAEAPGRHTLLAMHHNPMQIDNHWHDSMMI
DNPQGLFKLLTRWPQVRVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNLA
PGYRWIKLYQDGSMATGVRRVQDALWHTGAQPGPDSARAA
>A0A103IU81|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Burkholderia cepacia|TrEMBL
MLLAQISDLHIKRPGQLAYRRVDTAAALARCIDRLNALVPRPDAVLVTGDLTDFGHDEEY
GNLRGLLAALEIPYYLMIGNHDDRAGLRRAFADRAELQDGEFVQYALDVGAVRVLALDSQ
VPGASHGDLCDARLAWLAAQLDAARDRPVIVALHHPPFAAGIGHMDKLRLAPAAAAKLDA
LLRAHPNVERVLCGHVHRTMFTRFGGTLASAVPSPAHQVAFDLRTDAPSAFRLEPPAFAV
HRHAPDTGMTSHHVYVDEGAGPYPFYEPTGELVD
>A3KI13|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces ambofaciens (strain ATCC 23877 / 3486 / DSM 40053 / JCM 4204 / NBRC 12836 / NRRL B-2516)|TrEMBL
MLLAHISDLHLDGSERATRRATRVMDHLRALPHPPDALLVTGDIADHGEEAEYEEAARIL
SAPFPVLTCPGNHDARPAYRKALLGQEPDDGPINQAHHVDGTAILMCDSTIPGSDQGLLD
TGTLAWIDTELTALPQDTPALIAFHQPPVALHHPLPDSYMLEEPERLADLLAAHPQVAAV
LTGHAHTAAASTFAARPLIVGPAVTWTLRLPWEGDQAADRDQPPGLAFHILDDTRRLTTH
YRVVI
>A0A0S4UJY1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ralstonia solanacearum|TrEMBL
MHFLQLTDLHIKPPGRLAYRRVDTAAYLSRCVAHILAQPARPDAIVLTGDLVDAGAPDEY
AHLRALLAPLDAAGIRMLPVLGNHDARAAAREAFADWLAPIPAEARDPQAFQYWTDIGEV
RLIVLDTLDTGAPGGRLGVPRLDWLHDALAAEPARPVVIAMHHPPFATGIGHMDVQSLAA
EDIPAFAQIVRAAGNVERILCGHLHRAIDVRFAGTVASTCPSPAHQVALDLDPEGAPGFV
MEPPAYRVHAWVPGQGLVSHLAYVGTFDGPHPFFEPDGRLID
>A0A655DSG1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mycobacterium tuberculosis|TrEMBL
MDADDRLGELLEQLNQSGLRPDAIVFTGDLADKGEPAAYRKLRGLVEPFAAQLGAELVWV
MGNHDDRAELRKFLLDEAPSMAPLDRVCMIDGLRIIVLDTSVPGHHHGEIRASQLGWLAE
ELATPAPDGTILALHHPPIPSVLDMAVTVELRDQAALGRVLRGTDVRAILAGHLHYSTNA
TFVGIPVSVASATCYTQDLTVAAGGTRGRDGAQGCNLVHVYPDTVVHSVIPLGGGETVGT
FVSPGQARRKIAESGIFIEPSRRDSLFKHPPMVLTSSAPRSPVD
>A0A173TNW3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Anaerostipes hadrus|TrEMBL
MKVIQISDFHLRGDGKLSFQKADTMKALHQTIDYFCSMKDYELPEFFVVTGDLSEGGTRE
GYEFMREGLRKLPRPVYIVPGNHDKRDFFLEMFTEETPVKEDIKPYICYTIDEYPVRVII
IDTSKPSCHSGGLSDRVAEWLEERITEYPEKPTLVFTHHPPFVTGLPAMDEGFDQADRLA
QILNKHENVTLCCGHMHTAIFTSWHKIPCVTCPPIAMQMEVDFRGKNDINLTEEEKKEEF
KGGGDRFFLGNPGYLIHDLQGDRINTHYQTIPTGADYSGPWPFKYYEGEED
>A8I3L6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chlamydomonas reinhardtii|TrEMBL
MVALPPPPPPVIEEVERLLAHADGWQFNTWRLAEATGGHALSALGFFLLQREGLIDKFKI
KRTRLARLLLAVEQGYPSNPYHNATHAADVLQTLHVLLHGAGLATNYVDRLGLLAAYFAA
IIHDHGHPGLTNDFLIATSDALAVRYNDRSPLENHHAASAFALLLRPECDITSQLSTQDK
AAFRKQVIDMVLATDMKQHFAILSHFKTRLLTLQVGRVAAVLLAGKGCRARVLHTCVALK
VADIGHLGEVLPVHERWLGVLEEEFFNQGDKERELGIPISPLFDRAKQGVSKSQVGFYDF
VALPL
>A0A1X6ZZH7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseovarius gaetbuli|TrEMBL
MTADRAEATHDANTRIIWLSDLHFEDHGTVLGHDPRARLDAAISFINQSDAEADLCLISG
DMVETATAANYRALAAELDRRAIPWWPMTGNHDKRALFLEHLRLPKGAMPGFAQYAIELP
QARVICLDSLNPGAASGLLCAERLDWLERALLAEPDKATLVFLHHPPMALDLPMLDPDRL
ENGAALMDLLARFPAVRQLCFGHVHRPVSGHIGRIAFSSLRSALYQAPPPVPPWDWESFT
PAVEAPELGLITLHDDQINIAFLPFCTASLGVNGVPNDEKAPLTCAQFPIQPSAPPAMFL
S
>A0A1V5U7N6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Dependentiae bacterium ADurb.Bin246|TrEMBL
MNNIRLFHISHTDLDGYACQFLTNEVFSKKHFYNANYGLEVKQAIKQVITEIKNYQDEKL
LLLISDLNLNQQESDELDKDIKSLKDDGFDITLQLLDHHITGKSSAAKYDWYFLDDKRCA
TKIVFDYLLKEFKAPLNDYKEWVDTVNAVDIWLENEKKNFEFGKVLMSMITKAREINSIL
FNSLDRDFKFYLLKNSIGFLSLKDAPIILDNSVHSLKKEFLKDGFDDTLDNLSASYLVKS
LDKIKDDLTIYYNGQKGLMTYCLGAISIPANSFLRANSDYDFFIDISRKGNASFRADGKL
DVSQLASKLANGGGHVNASGCKFDDFIDTINLQEVRAYIQNKLNNLK
>A0A2G8Y297|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii COUG|TrEMBL
MNASSKSMRIGFPNGSPGVGDPGMPSPVLPLCQTASHALGNARSQASEGRTDGASDRSIS
ELEKESCQRGHRLEAREASEILAAESAQEEHRSCARKPRASRVEVDTLAESPERPSQAYV
PTESLGLGPRRTVPLCSAGSSASAGSWISSGDSVREETRQIRGRDAANKCSTAELSVSVE
RSCGHHEGTDTATQCVAARPEALCAAFLPAPSPGVSVDSAAAAVGPHCAAEVPVGADRRR
RLFAAPFSALPQTDACSRGSATPPSLFSRQPFDTVRSSSSLRDGGNAWTRLLDGCSAHPT
SSSSSVSPPVLGSIRTLQQSLPSSDDDTTSARTDTSLTPAKQVWLLPLHGHSLSQSSSSS
FREFRVTLGSLTGFRSSDSRTSASGSERRRSKSRGKPQGRSGSLGRDNRRKSELSGRDES
LSWIARRWWTRDEDSRWSDSRVRGSVALRAESTSDSRCENNSCATWLCRVVRRLPVAPAQ
TFCDEDEKRYTEGVLRFSRRRTIPVAVAVVIVSFLYTVPFVLHALQEFVQTPSADRKVFV
FFSSRAPPRSPVAAGAAHDAQLDVSAADSALQDVGGKDAFFVVASLVFWLLSLASVLVFA
FFAVFGALFVRIEKILCVLTAVNFSALALAECFQALRISSCPPSLFPEQAAAEGGSDADR
CAQVHSGLTPELLIIQTFFLIVLDFGFCVRLRISQWLHLCAVSLLLSLAFVYSILLPLPA
YLIASLWGQAVIGGFVLGSLHLAALTLETERRRVFLHFEVAKARVAELQERAQTDKHHGK
VAVFGLIHTLKQMDACMNELQNLAPEAADVLFQLDALRVQCLDIATSSENFYAVNMNALP
TDVRDLLQLETRNAFDGTTFRDTQVLLRDSLSPRKGVLLDLSLGPACGGVSRERRASCSA
AVSSTSSRESDRREAIARDPDLTETERRDAERRGMERKATDDRQKKARFLVVPQLVEHEL
LCHVGILWSLDLFKLDKECNGNALLHVGYQLLAPLLAAGYLTCSREVVLDFLYSLQCLYI
DTPYHNQLHAASVAHLAFSICHFLDLFAPLENAPGDAAASQPVFAQYLSLAIAALGHDAG
HPGRSNAFLVQTSSTLSVVYNDRSILENYHACLTFYTLSHRKSNIFRGKTVTQYRDVRKK
AIELILSTDMSLHFEFLTRVAARRENPDFNFVDREEDRALVLSLAIKVADLGHCALDWEA
HTLWSARLKEEFLAQGDEELRLGLPVSPLCDRTQQGQLARSQANFIEFLFLPLAQHLAAV
APDDRFEATVVTRARQNISMWEGAQDEVDQASAK
>A0A5P2ZZB8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodobacteraceae bacterium|TrEMBL
MIKIVVLSDLHLRGRGDPANGLDPHDRLRLGIDWLNRRHADADLCVLAGDLADVGDRDAY
ELLKHQVMRAKVPVEMTIGNHDDRDTFLKVFGEAYRAETGYIDKSIDIGGYRVIILDSAI
TGEPAGRLEPAQLHWLGLRLDEAADRPVIVIVHHHANPLMTRVDRILMQNGTAFARVLSR
HKDIRQVIAGHVHYTSTAIWHGIPFTTLSGGHYSVRALLDPDEPAPHLTGPAQMAVILAG
TDGTIVHFDDYINGNARIGQP
>A0A212LEC7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Pleomorphomonas sp|TrEMBL
MKLIQVTDPHLRRRGELVCGLDPAANLEAAITDINRHHADADLVVITGDLSDDGSADSYR
LLAETIGPLVPPSRLLLGNHDDRAAFSAAFPDAPAEDGFVQSATDVGNHRLLFLDTLDEG
AVAGRLCEHRLAWLDNRLAEAPASALVFMHHPPFDIGMPPLDGVKLADPRAFAEVLRRHG
NVRHIFAGHVHRLCSGTWNGIAFSTGRGTNHQTAPLFGAKDFAVGFDTPAYNVILVDGPD
IVVHAQEIGRT
>A0A090P8E0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio ponticus|TrEMBL
MNNYFNWSAWPNFGNEGNGFKLSKYTYTDLPQYQWQPVKGTSMQVMAMPLAHSGGQSTAF
ALKDSDGDLFVYFGDTGPDAVEKSDALSKVWQTLAPFVKEGQLKGIVIEVSFTNKTPDKM
LFGHLTPNWLLKELKALETLAGKGSLEDLDVVLSHIKYSLKKGEDPQVVIKRELEQGNKL
GVNFHFPAQGDALTF
>A0A0P1G054|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Tritonibacter multivorans|TrEMBL
MKFLQFTDIHLTKDGETIGGRDPVLNFRKGLAHAMEFHADAEALFITGDLSDWGDAEDYQ
KLKDILRDVPVPVYPLIGNHDERALLRAAFPDLADPNGFVQYTVPLSLGTAICLDTWGPQ
SHAGHFCETRAAWLQAQLSRLEGPVWIFMHHNPVALRIAPMDKIMLLDADRFAATIQPFS
GRIRHIYHGHCHLPLAGSLHGIPLYAPRGTNHAGWADFSATRLLSSAELPEAYAVTFADT
ASTMTHMVEFGYAGDIKGEGSPDYADWDRTTMVR
>A0A7W7IU73|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Flavobacterium nitrogenifigens|TrEMBL
MNNFNRFFLCLLLISSNVFSQKEKSSFQVVPLGVKGGINEKNLSAYLLAPINTNDYICLD
AGTINAGIEKAIEKKTFKVSTSEVLKKYIKGYLISHAHLDHVSGLIINSPADSSKTVYAT
SKCMEMMENHYFNDQTWANFGDAGPGFPLKKYHFQTLNLGEEIPLTNTKMTVKAFPLSHV
NPFESTAFLVKNENNYALYLGDTGPDDVEKSNNLRDLWTAIAPLVREKQLKGIFIEVSFP
NEQPDKFLFGHLTPNYLMKELHVLEDLAGKGSLENFKIIITHLKPPAKNIAKIKGQLKAQ
NDLGLKIIYPEQGKKFEL
>A0A4R8R5K4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mycobacteroides franklinii|TrEMBL
MTDEQDPQHMSRRQLIRHTAWFGAAVALTVAGGEVISHVAGSQAAATTRPTLRFAQISDS
HIGFNGTANSNVVDSFGHAINQINNLGYTPDFVIHTGDLTHLATDAQFDQVKQMLSGLST
PHVFTVPGEHDSVDDAGQKYRNVFGNGTRGDGWYSFDIAGVHVIGLVNTLNLKKLGHLGN
DQLEFIERDLAPLSSDTPIIVFSHIPLFAMYPEWGWGTDDSAQALSYMKRFASVTCLNGH
VHQLFTKTEGNITFYSGTTTAYPLPKPGDGPAPKPVTLPAGQLHDILGIREVSYLKGSQA
LAIKEDKLT
>A0A086JVV4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii FOU|TrEMBL
KVMSMIIKSADIGHGTLPWADHERWCNLVVQEFYEQGDEEKRLGLPVSFLCDRDQHDREF
FKSQVGFLDFVVKPLYEELKALETQLNLNPQLPIENICLKNLQENISEWKKKNEERRASL
EPAGLEVGGA
>A0A8G2AC11|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella quasipneumoniae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QMARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFID
SSRAGTSKGWLTDETIGWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A1K1LES3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Desulfovibrio piger|TrEMBL
MEILQLSDLHLRGDGKLSFRKVDTPACLRTAAAHLRALTRMPDAIVITGDLADSGDERAY
HMIREALGDLPVPIYAVPGNHDRRDRMRAILKGWVPEESPVPPRVCHCVDMGELRLVLLD
SMEPGSHSGHCPGAMARWLDACLQEDGSRPALVFMHHPPFITGMGAMDEPFEGADLLRDV
LARAPWARLCCGHMHRPIFTSWAKGLALTVPSISMQIDLDLSPGGGDTFRMEMPGYMLHH
WDGSHLNSHVCQIPADVDFSGPHPFADSVNPVED
>A0A0K8P1L7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ideonella sakaiensis (strain NBRC 110686 / TISTR 2288 / 201-F6)|TrEMBL
MRAEDPPAPLLLAQLSDPHLGLSPAAFGGQLDTTEALQRAVAHVAALDPRPDAVLLTGDL
AEHGRPEEYALLRRLLAPLPMPVYAVPGNHDDPAAARAGLDPAQMPVDADAPAGRCCYRV
ALGGLQLVALDTVVPRQPHGALDAAQLDWLARTLAACADAPVLVFMHHPPLPTGLAAMDA
CRLLDGAEALAARLRAHGRVEGVLCGHLHRPVQLRFAGTGLHVAPSVAHQLALDLRPAAP
LRARLEPPQVSLHRWTAELGLCTHLSRVDTVEPDWPV
>A0A422NZV1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Trypanosoma rangeli|TrEMBL
MECGGTADVAGASQLSPVPSKLMEAVKNVVGAATWVFPQRFSDACASGNDTGNGLETACA
VLDFVAGHLAEWDRLASESAQTQAANALFSQTLVDLEGKSETWRATILALVKKLQAAQAE
QRRSLQEKDSRIAALAASLDVLATDAASAVEERDRFMHRCEDLERSLCLHAEEQLAESRE
AERLRRDFELLRGELDSVRTPSSNDVVAASGDGAVDAGEQHMCPQRDVANFHATIACLTS
ERDALQNGLDALTHTLAAANERVVSLEEEKRAAAERLRALQDDAERLLQEIAHLKRSAAA
SASHPETSGTTAENSAGATRDHQPPESHRRWFLQPVEYCRFDGTGLPAPVVDFTSILGAL
DADHPAFADGSECARSPGLFFHIGCAIAEKLEFFGDSPPIALGAWKRFLLQLQSGFRDTL
FYTADHAAACAQFFYALLVHSGMVPHMSRAELLAAVTAALCMDYGHPGVSGCLLAAAQDP
AAAGIHGCILLERRRLQDLGDILAHKPFNFLDDSAATHSLLDDVRALLIPDELHGHCSGL
MRACLGPMLDGPLQIESRLVRCRLVQLLLRLSQYAFCMRAFDVNERYAERWFGMMQRQAK
VATDLGIYGFDVPHSTPTAAETQLQLIELTVLPLCRIAAEVFPPLHACEKALRANHAAWT
SRAAQLPTGIVADEAFKPLLHPGIIPSHVDGVAGENAAASVTGTRALDEVHVSASRHVDS
GSLLVNTACFLAFQKEMLAAYEESMTLRHLLEALLAPIEALPAPQDVAT
>A0A5P9I6L5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseovarius sp. THAF9|TrEMBL
MQKILVFTDIHFVPEGETIIGLDPAERFAQGLAHAQQNHPDADCILITGDLTHHGSAPEY
ERLHAELSKARIPVSLMLGNHDRRGPFRSVFPDTPQTPDGFVQDVIDLHDARLILLDTLN
EDADDTHSGLLCDARLDWMEAAIAGAGRRRVILFMHHPPILTGFGGMDWIGLKSRRQLAA
RLEGHDNVHQIVAGHIHRTIQGGFATGAGNRIPTAIFKSPCHQMPMALGFQDPSLSIDEP
GAYGLLLLTPEGIVVHTEDFTLPPGAGVRYDH
>A0A165MLE3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodococcus fascians D188|TrEMBL
MSGTVESVGLPVPWYSVYGNHDTLLLGTFDLSSQLHALAVGGRKAYTLEATATSALAGYA
STGSPLQRMVDALGVGSGARPGFRAVSADPARYLFEQREFMQEHFETTPTPGPIGHGFTE
HNLDSGETWWAADPTPNVRTFGLDTCNAVAGPDGAVPEDQFDWLTQQLEKAQAERKLVLI
YTHHNSLTLENRAQRPGQSVKLYGADEFIDLLLKYPVVIGWLNGHTHQNQILAHSRDGRG
FWEITTASCIDFPQQQQVVEIVDNRDGTLSLFTTVLDHASPITPGNSGSYLDLASRSREL
AANDWAENPLMRRGSRLDRNTELLLPAPFDLSTITDAALEQQHLDEHARLIAYETRQGR
>A0A2U1S8K7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Methanobrevibacter woesei|TrEMBL
MTIIAHISDLHVSHTEFDEDVFFQAVDEINNLQPDMIVLTGDLTDQGYYRDYLLVKDYLS
RFESPLFAVPGNHDSRNLGHQTFEELIGERSWKLTKDDDFVVIGLDSSTPDVDSGNIGRP
QQLWMDHILDDCVVNERFSVVALHHHVIPIPETGRERNVLSDAGDILKTLVNHEVDMVLA
GHKHVPNIWKMNNTLFVNAGSLCSKKLRGKDTNSYNTYFIDDESIKVVLNRVAGDKILLG
EYPRNIL
>A0A0E7UEJ0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bordetella pertussis|TrEMBL
MSDSAAPVRADAPAVLVQLTDMHLFDEPHTAMLGVDTEASLQAVLRQVGEDGLNPDALLL
TGDLSQDGSPASYQRLHALLAQTGLPVRCLPGNHDAPATLRAELGAWSDPVLDLGAWRIV
LLDSTVPGSNGGHLADDQLDLLSRAARLAGDRPLLVAVHHNPVQGDPDWHDTMMLDNAQL
LFQRLQRLPQARVLLWGHVHQEFDCRRHNLRMLATPSTCFQFVVRDGKHCVDDAAPGYRW
LKLYADGSLATGVRRLDGDRWRALLRQNAG
>I4L0M3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas fluorescens Q8r1-96|TrEMBL
MPSVSSLTTADAALLVQLSDSHLFAEADASLLGMNTRDSLWAVIDLVLKQQPDIDLMLAT
GDLSQDGTLESYAAFRQLTARIDAPARWIPGNHDEPQVMLEAAVKSTLLNPVVDIGNWRV
TMLDSAVPGSVPGFLAEEQLILLANALSEAPERHHLVCLHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEVDRMREGVRLLASPSTCIQFEPGSEDFAVGSQAPGYR
WLRLLPDGRLETGVERVVGFAFTPDYGSNGY
>G7ZAD3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Azospirillum lipoferum (strain 4B)|TrEMBL
MIIVQITDTHIKPPGRLAYRRVDTAPFLERAVAAVLALNPRPDVILATGDLVDAGHAEEY
ERLLGLLRPLDIPLFAVPGNHDERAGLARAFPDLAARVGDSPFFHYTVEDWPVRLIAMDT
VLPGSGAGEVCAERLSWLDARLSEQPDRPTIVFQHHPPFATGIGHMDRLGLSGADAMAAV
VRRHRQVERVLCGHLHRPIQVRWAGTIASTAPSTAHQVALDLRDDAPSAFVMEPPGYQIH
MWRADTGVVSHTAVIGEYDGPYPFFKDGKLID
>A0A1Y5PEP0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Microbacterium sp|TrEMBL
METVQFGRHAPARRVIVHLSDTHLLAGNAPLGGRYDTAANLAATLAAVERTGVAPDALVF
TGDLTDLGEPDAYRALRAAVQPLADRLDAPIVWVAGNHDERPALRGALLGLEPSGEPVTG
VWDLGGLRLIALDTSVPGWHHGDLDDGQLTWLRGILAEPAPLGTLLALHHPPLPSHIPFF
DILELRRQDALAEVIAGSDVRGILAGHLHYSTSGSFAGVPVSVAAATCYTMNLQRPATEV
NGMDAGQSFHLVHVYDDTITHSVVPVVAAETAETFSADWVARMAELTPEQRLDAFSRKR
>A0A446B200|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. JV241A|TrEMBL
MPQPSIPLRDAPVYLVQLTDSHLFADPQGTLLGMNTRDSLQRVIERVRDEQPRIDLVLAT
GDLSQDGSVESYTCFRDLTASLQAPARWLAGNHDEPLPMEQATQGTALLDPVVDMGNWRI
LMLNSAVSGSVPGLLDDGQLRLLEQALSEAPERHHLICFHHQPVPIECAWMAPIGLRNAD
ALFAVLKGYPQVRALLWGHIHQEWDQVRDGVRLLASPSTCIQFEPRSEDFKVGEQAPGYR
WLRLQPDGSIDTGVSRVTGFEFTVDYEGDGY
>A0A8D0DZT3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salvator merianae|TrEMBL
MTEPSNRKDGFKKCRSATFSIDGYSFTIVANETGDKNARPLSRFARSKSQNCLWNTIIGG
LTGNLKEKQKPTIICDPRPPEEILADELPPVESPEALVKTSFRLRSLVKQLERGEASVVD
LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDSVPSEVRDWLASTFTRQMGMMLKR
TEEKPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIGVLKNVDKWSFDVFALNDAS
GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV
HYLLFKTGVAWLLHLDWDRNTNKICVKDFYHLRRNQRMFILLFCRSDTAILYNDRSVLEN
HHLSAAFRLLQDDEEMNILSNFSKDDWREFRTLVVEMVLATDMSCHFQQIKAMKNALQQP
EGIDKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDKEAELGLPFSPLCDRK
STMVPQSQIGFIDFIVEPTFTVLTDMTEKIVTPLIEEASRSGMTGFRRSSLNSISPSEVK
RSSVKSTGSEGSASLNCSLLTVDFKCFKATWTEVVQQNREKWKAQATKEEKAKKEAEDNL
QQGTDEKKTDDNEGKNKEGHSGACKSTEASKSNVNGTRQTGGSRHDASQGKNVTQAEKAS
EPNSTAGEQKRHVQNGKPVDRFMQWGSYSIRPPIRSSKKPNFASTSTSFPPFQKKSEDYL
VRYKLLDQRGRMKKIQHISQHWNRK
>I7K238|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactobacillus gigeriorum DSM 23908 = CRBIP 24.85|TrEMBL
MITSDLNTEIWVISDTHLIADSLHDNGQAFSRMQKTSQGKDLYYQETALSTFCRMAEIKK
PAAIIVTGDVTFNGERVSAERFAKIFTKLSTTKLLVVPGNHDIFDGWAREFRGKKQFFAG
EISPRFWKNIFQKSYALADSVDYNSLAYAVQLNPIYYLLMLDSNYYGKEETTETPHTRGA
IGKEQLKWVEERLKYASKNNLRPIIFMHHNLYAHNPAVNRGYVLDDAVELRRLCSRYNVK
LAYSGHIHAQNIMGPQDMTPTTEIVTSSFCSNDQGYGVTRIHSHHITYVRKEFNMHKYLT
EEEKQNYTLDHFDNYLENLQLGTIAADLMQSDLKKYHNNLDLIRKMGKLFAKMNYNFYTG
HNHLKAQELNNIHASQEYQTLIKQHPEYRIYLKTLYDTSDHSNLQVKITY
>A0A4W5Q0P4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Hucho hucho|TrEMBL
MGSNTTWARRPARRSDDKPKFRSIVHAVQAGIFVERMFRRAYTAAMPDQPVAVVNCLRDI
DRWNFDVFALNTACHDHALQTLFLELVTRYELNSRFKIPISCLMSFLEKLEKGYGKHSNP
YHSSVHAADVTQTLHCLLLRTGLVHWLTELEVLASLFAAAIHDYEHTGTTNNFHIHTKSD
FAMIYNDRSVQESHHISAAFRLLQDDLSNIFMNLSREEWMELRALVIEMVLATDMSSHLV
QVKAIKGCLQQQEGIDKPKALSLLLHTADISHPSKPWGLHSRWTKALMNEFFRQGDREAE
LGLPFSPLCDRNSTLVAESQIGFIDFIVDPTFSLLTDMAEKIVIPLVEDNPETLEPSNLW
KESSRGLQWSLAHITSELVTFRSTWTRHTEDNKFKWKESGSNGNVTDFY
>A0A330LXL4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Shewanella benthica|TrEMBL
MLKEAISYSLEEKASVRIVQVTDPHLFADPNAQLLGVNTAKSLESVLNTIKAVDYPADLM
LATGDISQDYSGESYHHFVRAITPLDMPCHYLPGNHDDPRVMNLHMQGAKIFGQRRILAG
NWQIIMLDSTVRGKPGGHMSDSEIEIIRSAVADQPERHILLVMHHNPILIKCRWLDQHCM
DNGSDFIEQVAQIPQVKGLLWGHVHQELHKEHQGMHGIIHLMSTPSTCIQFKPLSSYFAL
DAKQPGYRLLELKADGSMITNVYRVPGDKFSSDRNASGY
>A0A0B1SHU5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oesophagostomum dentatum|TrEMBL
LYIAELKSLILLPQAFEIPSSVFVTYLLNLEHHYRTNPYHNHIHAADVAQSMHVLLTSPV
LTEVFSDLEVMAAIFAGAIHDVDHPGFTNQYLINSSEFLSFSKYPSLLSHFNFYSS
>C9XU94|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cronobacter turicensis (strain DSM 18703 / CCUG 55852 / LMG 23827 / z3032)|TrEMBL
MDNLPKDVVMSSQPFVTQREVTLANDTTLMSTTDLQSYITHANDAFVEVSGYTLEELTGS
PHNMVRHPDMPKAAFADMWYTLKQGEPWTGIVKNRCKNGDHYWVRANVAPMVRSGKITGF
MSIRTKASAEEIAAVEPLYKALREGRKPRRLFKGLVLRNGVWGKLPTLPLRWRLRGVMAA
LFVAWTAVMACTGTPLLAPTLMAAVMLLLGGAVLEWQIVRPLENVARQALRIATGESQSI
AHINRVDEVGVTLRAIGQLGLMCRWLMNDVSGQVSNVRSGSETLARGNEDLNERTRQTVV
NVQQTVTTMNQMAASVQNNSATAAAADKLSSEASDAARLGGQTMQTVVQTMDEIADSTQR
IGSITALINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLANRSANAANDIRKL
IDASASKVASGTVQVHDAGRTMQDIVNQVENVTRLLGQISQATTEQADGLSDLTRAVAEL
DAITRKNAALVDEGAQVSSMVKYRAGRLQDAVTVLH
>A0A1V6DKL6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Verrucomicrobia bacterium ADurb.Bin118|TrEMBL
MRWKAAQIGVMPVHLPPVTRREFLRRSLLAGAGFLTATASWAAPRAPDPHTWALMADIHI
AAKRTELRRGIVMAWHLEQAISELLAGPRVPAGVIVAGDLALNRGERGDYATLLELLQPL
RAEQVSAHLAMGNHDHRENFLTAFPETLVRERPLTPHLVGIVRALRANWFILDSLEQTLA
TPGLLGAAQLAWLERALDAHQNRPALVVLHHHLSTKQGGALKDTQALLEVLRPRRQVKAC
IFGHTHVWGIKEDESGIHLINLPPVSYVSHPSHPNGWVQAELERRGMKLQLRCVDPEHPA
HQQTVSLRWRKG
>B8CDS3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thalassiosira pseudonana|TrEMBL
MKKAERGGKYAKELSKAFAQAKEAGKGEAGKTEASRNIGSISDSIGWMGGYFLPDEFDIT
PRALCSFFRMVEKDYPRRKVNPYHNNVHGADVIQSTHALIQMGEVNMALAYTPFEIYTIL
LAAALHDVRHPGTNNNYQINKQTELSLIYNDNSVLENMHASRASYLLKVGEEIGARNGED
SGGIMGNMDGDQRKLVRTQIIRSILYTDMSRHFAEVAKMKRYIDAHAKLRDKMLPYILHL
ADISNPSKNPRVSIEWSNCAYDEFFLQGDKEAEEGMAISPLCDRTTTNIADGQVGFINFV
VKPAFEILTQCIPNVECVVNQLNENLKFWEKEMVRMKEEKEMLER
>A0A655FXZ0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mycobacterium tuberculosis|TrEMBL
MSVASATCYTQDLTVAAGGTRGRDGAQGCNLVHVYPDTVVHSVIPLGGGETVGTFVSPGQ
ARRKIAESGIFIEPSRRDSLFKHPPMVLTSSAPRSPVD
>A0A378TR64|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moraxella lacunata|TrEMBL
MTYPTHLSAPSDFIIAQISDLHLSTHAPTNTDKFLKVLDFALTFKPNLLLLTGDLVNDGH
LPLYDWLFATLDKTNTPYLCLAGNHDVTHEIGHDLPFDKRTFLPIAKDDRLIDTHRLIIE
LPHATWQLLAVNSALHGHVYGRLDDAQLAFLKTHLNHAMPTLIALHHHPTPVGSAWIDEH
MLQNGNEFWAILNAHTTNTTNRPHVLCGHVHQAHILQQNGGTLYTCPATSRQFAPHRDEF
GIDDVASGFRLLQLHNNRTLDTWVKRLDNSEFGIVK
>A0A8C7EMT1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Neovison vison|TrEMBL
MGSTATEIEELENTTFKYLIGEHTEKMWQRLKGILRCLVKQLEKGDVNVVDLKKNIEYAA
SVLEAVYIDETRRLLDTEDELSDIQTDSVPSEVRDWLASTFTRKMGMMKKKSEEKPKFRS
IVHAVQAGIFVERMYRKSYHMVGLVYPEAVIVTLKDVDKWSFDVFALNEASGEHSLKFMI
YELFTRYDLINRFKIPVSCLISFAEGLEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGI
MHYLTELSVMTAIFAASVHAYSANGSETNEHVVLRSDVALLYNDRSVLENHHVSAAYRLM
QEEEMNVLINLSKDDWRDLRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPEGIDKAKTMSL
ILHAADISHPAKSWQLHHRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMVAQSQIGF
IDFIVEPTFSLLTDSTEKIITPLIEEASKTDTSSYGASSVDLFRRSNMKGTMNDGTYSPD
YSLTSVDLQSFKNNLVDIIQQNKERWKELAAQGEPDLHKNSEDLVNTEEKRADAHS
>A0A2Z5K9M2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces sp. Go-475|TrEMBL
MLVLAHISDLHLDGSARATERAERVRDRLWELPGQVDALLVTGDIADHGTEPEYEEAARV
LGLREGDAPFPVLTCPGNHDSRAPYRKGLLGLPGTEEPVNSVQVFDDGAVLMCDSSVPGR
DDGELDAATYDWIETTLDELDGSLPALLAFHHPPVALHHPLPDAYPLRDPGRLAGLLERR
PEIAGLVTGHGHTPAAGSFAGRPLVVGPGVTWTLRLPWEGEQAADREAPPGLAFHVLDDA
GRLTSHFRVVT
>S8F1W3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii (strain ATCC 50611 / Me49)|TrEMBL
MNASSKSMRIGFPNGSPGVGDPGMPSPVLPLCQTASHALGNARSQASEGRTDGASDRSIS
ELEKESCQRGHRLEAREASEILAAESAQEEHRSCARKPRASRVEVDTLAESPERPSQAYV
PTESLGLGPRRTVPLCSAGSSASAGSWISSGDSVREETRQIRGRDAANKCSTAELSVSVE
RSCGHHEGTDTATQCVAARPEALCAAFLPAPSPGVSVDSAAAAVGPHCAAEVPVGADRRR
RLFAAPFSALPQTDACSRGSATPPSLFSRQPFDTVRSSSSLRDGGNAWTRLLDGCSAHPT
SSSSSVSPPVLGSIRTLQQSLPSSDDDTTSARTDTSLTPAKQVWLLPLHGHSLSQSSSSS
FREFRVTLGSLTGFRSSDSRTSASGSERRRSKSRGKPQGRSGSLGRDNRRKSELSGRDES
LSWIARRWWTRDEDSRWSDSRVRGSVALRAESTSDSRCENNSCATWLCRVVRRLPVAPAQ
TFCDEDEKRYTEGVLRFSRRRTIPVAVAVVIVSFLYTVPFVLHALQEFVQTPSADRKVFV
FFSSRAPPRSPVAAGAAHDAQLDVSAADSALQDVGGKDAFFVVASLVFWLLSLASVLVFA
FFAVFGALFVRIEKILCVLTAVNFSALALAECFQALRISSCPPSLFPEQAAAEGGSDADR
CAQVHSGLTPELLIIQTFFLIVLDFGFCVRLRISQWLHLCAVSLLLSLAFVYSILLPLPA
YLIASLWGQAVIGGFVLGSLHLAALTLETERRRVFLHFEVAKARVAELQERAQTDKHHGK
VAVFGLIHTLKQMDACMNELQNLAPEAADVLFQLDALRVQCLDIATSSENFYAVNMNALP
TDVRDLLQLETRNAFDGTTFRDTQVLLRDSLSPRKGVLLDLSLGPACGGVSRERRASCSA
AVSSTSSRESDRREAIARDPDLTETERRDAERRGMERKATDDRQKKARFLVVPQLVEHEL
LCHVGILWSLDLFKLDKECNGNALLHVGYQLLAPLLAAGYLTCSREVVLDFLYSLQCLYI
DTPYHNQLHAASVAHLAFSICHFLDLFAPLENAPGDAAASQPVFAQYLSLAIAALGHDAG
HPGRSNAFLVQTSSTLSVVYNDRSILENYHACLTFYTLSHRKSNIFRGKTVTQYRDVRKK
AIELILSTDMSLHFEFLTRVAARRENPDFNFVDREEDRALVLSLAIKVADLGHCALDWEA
HTLWSARLKEEFLAQGDEELRLGLPVSPLCDRTQQGQLARSQANFIEFLFLPLAQHLAAV
APDDRFEATVVTRARQNISMWEGAQDEVDQASAK
>A0A378E8N4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae subsp. rhinoscleromatis|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDAQNMRYVVDDFATRLLFID
SSHAGTSKGWLTDETISWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A817PRS5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rotaria sp. Silwood2|TrEMBL
MPGRKIRLTSGSSLIIIGTSLTNLSSKTIKVSGTSKTKSHNHHHASRSPKASSTTTVIHN
DDGYGDDHRIGSHNEGGPTNTPFDLIEHDVTGLSKVYNLPKPDSFDALQIGSDRLRTIIA
ALHCNILVRKEDLVRNLDYVANVLEAVHQDETRRLMEEDDGALSEIEPDSVPNEVRDWLA
MTFTRSMSTIKRRPSDKPKFKSVAQAIRAGIMVDRSDVALIYNDRAVLENHHVSAAFRLM
RIDDYNILSEFSSDEYKNFRHLVIEMVLATDMSSHFTQLKTMKSLLSMPENIEKSKALAL
VLHSADISHPGKPWTMHHTWTELLMEEYFKQGEKEKELGLPCSPLCDRDNTLVAESQIGF
IQYIVEPSFVVMGDMLEKILKSLSVPDSELPSPSIPAKSIVSSPSPPPSPKSSNGSNPQH
DEQLENGRERKPSSMTTPISRLTTVRRPWIEYLKENRERWIREAEEEKRRRELKVIEEEP
>A0A8C9N7T4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serinus canaria|TrEMBL
MIWLSRCAFSTVKTLYMYAEPYIKILWSLVKQMERGEVSIVDLKKNLEYATTVLESVYID
ETRRLLDTEDELSDIQSDSVPSEVRDWLASTFTRQMGMMLKRTEEKPRFRSIVHAVQAGI
FVERYKLTRHSVALAMSFRLVSTTVDLLTVGNNVLQNDNLPDCTVISFQHWLTELEIFAV
IFAAAIHDYEHTGTTNNFHIQTREFRALVIQMVLATNMSCHFQQIKAMKNALQQIDKPKA
LSLLLHTADISHPAKAWDLHHRWTMSLLEEFFRQGNKEAELGLPFSPLCDRTSTMVAQSQ
IGFIDFIVEPTFTVLTDMTEKIVTPLIDEASLSGMPGFRRSSNLAAFSTGSEGSASLNCS
ILTVDFKCFKTTWTEVVQQNREK
>A0A290HE53|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sulfurospirillum sp. JPD-1|TrEMBL
MNHKIHHLSHTDLDGYGCQMVSAHYFNSIAFYNSNYGKEINECFNQILNNIQTSPLQKHV
ILITDLNLTMDQAKEFESKVSICDKEIMLFVLDHHKTGQECADAFEWYFLDSSRCATKIT
YDFFSALYGADEKLSKFVDVVNAVDIWLENEPEFELGKVCMGLVSGAKEVNKVMFPEENS
HYIFSLLTKAQEYFTCKDAHIALDDAIHNIKKQFFVTTANNTLSNLVSAYNVILLTKNRE
RMQIMYKEAKGILTYNIGNVSVIGNDFLTANPDLDFFMDITSKKTISLRSNGKVDVSKIA
AQIANGGGHHNASGGLLSNFKDAFIYDTIKSQVMSIIANKG
>A0A0M7MP40|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Achromobacter sp|TrEMBL
MLIAQITDLHMRTPGDKAYGIIDPAAFLGPAVRALNALTPRPDCVLITGDLTDLGKAHEY
QALREQLQALEIPYFLLPGNHDDRAQLRAAFPDHGYLQGQGPFIQYAVETYPLRLLALDT
VVPMKSHGELCDERLGWLAARLAEQPDRPTLVLMHHPPFLTGIEHMDAIGLLAGAPELER
IVARYPRVERVLCGHLHRTIFRRFGGTIASTCPGTAHQLALELGPRPTLQYIMEPPGYQL
HWWHDGALVTHHAVIGEYPGPYPFA
>A0A086JB55|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii p89|TrEMBL
MHISCVKGRIVARQIDNVFTVIFAIEVLGKFVSYGLEYLQDPIESFDTIVVLTSFTLLVL
GFYVSGIGLLRILRLLSALALLHKYPDSKEKRPELSAGNSSKLEKASSIVEGLLTNVHIP
KYFKTELEWVWDSILANKVYDSHVVENEEEEEDQATETIIAGSDASRKTQAAVRASRAQS
RASKLPHGSSSMVVGTTNGRISGQILETLREPDPRMMDAALYKSETRNLDPLTATVGGMK
NSPSMFAKGSKSSNMMGSSASKSFRTERNKKAIDIISVLYQASQITGAEQEQVNEAMRPF
DEWQWDALHAGDVCDMNLLPVVFVRAIATFPTIMTKFNFDLDRLFDFLKVVQTSFQKNVK
FHCAAHTADMIQAMHYFLTIGKLGALLSEYDVFLCHFCALVCHFGHPGVTNTFLVKSRHP
RAIRYDDESVNENYVASAISCLVAREEYNFFGDKLPLWQVFRLHMIDILLNFDISKSAHQ
VAMFRTKVSIKFTASTPADKQLLLTILLRAADYSFTCRQLALYSKWKDRMIDEFFAMGDT
EKQLALTVSPFCDRELTNVDKCHVAFAEVAVKPLMTVLVLGLAPHLQKDVLDTLEANQKN
LMQKLDKSD
>A0A1E3X9U2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Scalindua rubra|TrEMBL
MEEETVQNTISQLEERLNRRDFMKCSIAIGKAVFVGGVLIGNFTGCTTASKQVKKTKDKN
ETHIKFAHITDTHVTFTGRNGTSLFEESFNIFRDIIGQINEMDDVDFILFGGDNINNTDP
GTKGFDEFMNIMSGVKVPYFVQFGNRESSPIPPGVAVSKEQYAMKMKDHGLDIGRYWWSI
SPVPGLRILGLDTSILNHDNGEIPQKELKWIKEEITKYSNDMIVTLSHHLLLPTWGNKDI
PKWKKKYLLKNYQEVNTVLEGAPQVTMCLTGHHHISKIQTVNGLHYIASPATVQYPHAFR
TITINRDEAKLQFHQVRDQRIIELGRKFLLTSKNAEEYAGGKADDILAYCHGSEYDNNVR
LKLR
>A0A1A9XEL2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Glossina fuscipes fuscipes|TrEMBL
MATSRRKNDDKPKFRTVAHAIRAGIFVDRMYRRVNTTTLLQFPEDVVKTLKNLDDWSFDI
FHLAEATNGQPIKYLAYDLFSRYGLIPKFKIPPATLETFLHRVEEGYCRYRNPYHNNLHA
ADVTQTTHHMLCQTGLMNWLTDLEIFATILAAIIHDFEHTGTTNNFHVMSGSETALLYND
RAVLENHHISAAFRLLKNEDCNILSRLSREEYREMRSLIIEMVLATDMSCHFQQLKNMRN
LLTLNEATVDKPKALSLVLHCCDISHPAKRWNLHHRWTMLLLEEFFRQGDLERELGLPFS
PLCDRNNTLVAESQIGFIDFIVDPSMTIMSDMLEHILSTINVSPVEEPSTDTDPLSAFSK
RHSARRHKILKPWAIWLAENKKIWKEQAIKDAAARLTDKIEKVETVESENAEDTGKAEQ
>A0A238J9W4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pelagimonas phthalicica|TrEMBL
MKIIHLSDIHLCAPGGLVEGIDPHERLARAFGHMTEHHADATRLVISGDLTHHANPDAYK
ALKQALRLPPMPVRLMIGNHDDRAVFLEHFPDQSIDLNGFVNHCDQVGDLRLIYCDTVRP
KVHWGEFCEKRRAWLRDQLDLPGPVLLFFHHNILDLGDPCSDELSLNRADQAELRSLLKL
FQHKIRHIFFGHVHESLCGTMAGIAFSGVTSTVHQTIPNLAPSDKSPSGPLEPSYRVILL
RGEDVVIHQIPFAWEGEVVWHGNDWEDWA
>A0A379WLB9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salmonella enterica I|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISPAKRVLIGE
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTLLLLHHHPLPAGCSWLDQHSL
RNAGELDSVLANFRV
>A0A3G9FPS9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acinetobacter ursingii|TrEMBL
MPTSAQEYVLIQITDTHLLEQPEHEFVGMNPEQSFHEVMAHIQQHYPQADAIIHTGDLAQ
APRPKTYQRYLHFMQQLGIPFFHTPGNHDDEKYFPFHQENPQQPVLIELGNWRIILLNTA
VSNRVDGLVSTSQLEQLTDLLEQHQAHPTILACHHHPFEMHSKWIDQHKLKNSQAVFNLL
ERFKQVKAILYGHVHQNSSNFWQHIECLSTPSTSVQFKPCSEQFALDAVAPGYRVLKLKT
NGTFETVVQRLEHINHLINTEISGY
>A0A1X7BRF4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseovarius aestuarii|TrEMBL
MTKLLWLSDLHFVAEGLVQDHDPRQRLASAVEHINAHHRDAEFCVVSGDLVDRGTVEDYY
GVVAGLNRLAMPWLPMVGNHDDRALVRQHCPVPTGGMAQFIQYAVPADAARAVCLDTLTP
GNNHGTFCAARLDWLGNVLAKDPDTPTLIFMHHPPMDLGLPMRDRDRLQEAEPLLDLLTR
HKQVRQLCIGHVHRPIAGSLRGLPFATMRAVLYQAPPPVPAWDWESFRPAREAPALGVIT
LRGGDVQIHYEQFCAAD
>A0A1E7XCY6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lentilactobacillus sunkii|TrEMBL
MMVKIAVSSDNHFDLNKVPLTETISQQTAYLKDQQIDYYLIAGDLFNDFRKSADYVQRLS
SQVDSTHVFFIAGNHDMIRGISYEELENGRWPGYLNNQFVDIPNTDYRIIGLNGWYDYTF
AVNEDKTEDEFHRWKMAYWIDGLISQPMSDPDRERIVINQLRKQLQNAESAHKKVILMTH
FVPNQHFIHYTDDFRFWNMANAMMGSIQFQNVINEFQVEKVIFGHIHQRLDPIKIGETTY
YNAAVGYHNRRHNEWQTDDFISEWENQLKMFEVF
>A0A177H4X9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodobacteraceae bacterium SB2|TrEMBL
MTQFLQISDTHIVKPGSLVSGRLETSGPLKRLALRIAELQFEVGPLDGIVVTGDVSDDGT
AESYALFKSILKPLDLPIFCIPGNHDARAPFRAAFDGVGYLPKAGKLNWQHSLGALQVIG
LDTLIEGQGGGELDQDSLQFLKTCLADLKQAPAVVMMHHPPFKSGMAFMDSIGLQNGTEQ
LSEILAEYQGEILVLCGHIHRNISTRLAGHTVISAPSVCSSFLFNTHHDAPIGFLKQEGG
VLLHQWAEGFKSIRIDPVRGDGPFGF
>A0A139Y4G4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii ARI|TrEMBL
MWFYSYLRHPNDVPSLCTHIRSSNIFLRLGPQYYLPEDERKSLFVRTCHLLYYLASLLFL
TTLTTYTAIKIPSSPSTTTELLSQLFPFNSIDDCNERLSCKVDCVLYAFPDLNCAKDDGS
LLTFGGNSYSSLYFYHYPGKDVPLQKEARTAWERCYQIMRETTGRLQFLQQDRETVERTH
TCFAGCKTNGAVTFTQKLTDGTPVVFDSGTDWLQMAPAGSLPQDTRPACNPSEPPSLLCV
EPTDECQHVTLRYQVCIGDTAFCFDIVRILITIALGVVWNVVLDAFVVWAMSIDDSDPQN
LGRVASKCGLQIIATAIIVSSFFCLVASMTRILSMDANIARHGTLWTSFVLVIIIDQLFS
FLFSVLIWYAMLRRCGRQLPDESRFQYKIHPSPVLVKLKKATRKIVNYNGFEMFFTMLLG
WMVVDLTCRMILCQFFFDETAFLNQADRILEVVDFIILILFIVEICLRIAADGLKIYFSD
PINCIDFFLVFFGFGIRIVDFFIQINKGIGN
>A0A1Z5KB88|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Fistulifera solaris|TrEMBL
MPPFTIQIEASESSSKSLSSRHDGVSLSDPSQSNNTNIRSDGSTSNGSFTKDETKVVNHT
KLLVYVSLLLAGVAISITAYFFAKNKEQNDFEAEVSKTFETIDLSETNVENTMGQVHSLA
IAISSHATTMDQDAVWPNVTLPHFLERVSEAVSLTGSELIGFIPIVPISQKNSFEEYAAA
EWIEHHEGEIPKTIHNVKGEAERAESEKDTYAPLWQVAPQASDLDIVLLDMATFSWFHLL
EQDILEVKHTVMSGIVDVEYLLKATRPIELTEWHPRSVIMQEVSKSMTTGESDTENSKEP
GGFVFAVLPWKQFFQNVIPHELHGFLVEVNDHCGSIVTYRIDGHDATVVGNGNMHDSKYD
YLHMKAKFGSSAQYDGVETSTDHCHYIIDVYPTDELKELYTTHTPILFASAILGVFLFTI
GIFFCYDCAVERRQRRIASIAKRTNNIVKSLFPKNVQERIMAEAIEEAEKAEQAGKLKGK
GAYHVSMKDRLKETLASSMQGHQGDYAHKNVPPIADLFPSRTIMVCSTKDELNAEKVTYC
AQSAHLFNDTVISHKFADLVEITLGPDTGELGLRIGLHSGPVTGGVLRGDKARFQLFGDT
MNTTARIETTGKKNMIHISETTANILQAFGKGHWTKLREDKVNAKGKGEMTTYWLVKTDG
PKSTSSGISSSDGTGTGQEDDVDSVDARAALYVSADLDAVRRIEKDASIGQVFEEITEIL
DLPKFDAEATARQSALTPITLDPKAAEQLEAYVHAIATLYHDNPFHNFEHVSHVIMSVTK
LFSRIVAPEVSGDNRALHDHTYGITSDPLTHFAAVFAALIHDVDHQGVTNATLVDENNPL
ATVYNNKSVAEQNSVDIAWSLLMDDAFIDFRNCIYTTPAEYRHFRQLVVNLVMATDIMDK
SLSQARKDRWAKAFSDSSDEYGSSLNTMEEEMERNVNRKATIVLEHVIQASDVSHTMQHW
HIYRKWNARLFEEMMKAYRQGRTQVNPADRWYEGEKGFFDFYIIPLAKKLKDCGVFGVSS
EEYLNYAETNRKEWEAKGEALVAEMRRHFAGWICFTI
>A0A031FRV7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium oleivorans|TrEMBL
MRRAEHPAAERILLHLSDTHLRGPGPRLFDSVDGEASLTAALDAIESSGLAPDAIVFTGD
LVDLGEAAAYDAIRALVEPFAERLGARLLWVMGNHDDRGAFREHLLDQTPADPSAPYDRV
DELDGLRIVTLDTSVPGHHHGELSAAQLDWLSSVLATPAPLGTVLAMHHPPVPSVLPLAA
SVELRDQRRLADVVRGTDVRGIIAGHLHYSTFATFAGIPVSVASSTCYAQDLTVPVGGTR
PQDGAQAYNLVHVYDDTVVHSVVPIDVPRPLEYIDADEAQRRLRNAGVTGSVTRAARSGV
PALH
>A2S6I8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Burkholderia mallei (strain NCTC 10229)|TrEMBL
MPARCRPRTLKDRKIVRQAIKRCNQISHPVAPHISPLLSITYQKRQPARTTLNDRYFP
>A0A1S8SJD2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium beijerinckii|TrEMBL
MALYTISDLHLGFNVEKPMDIFGDKWKAHSDKIKENWLKKITEKDMVLIAGDISWSLKET
DSKYDLDWINELPGKKIISKGNHDYWWGSISKLNKMYENTKFLQNNFYTYEDYAICGTRG
WMCPGGDKYTSKDEKIYTREQIRLKLSLDAAKNSGFEKIIVMLHYPPTNDKFEESEFTRM
IKEYRVEKVIYGHLHGPVLLGKVLNGYLDGVEYMLTSADYLNFDPKKIL
>A0A1S8TC50|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium sp. BL-8|TrEMBL
MRLVILGDFHYSSLEEMDREKDKQIFDIRDKYYEKVIYNFLKTKGDYHISLGDLTNYGNK
QELEYVCSAMKNKGVNFINVLGNHDSYNSSKNDILSITKQERYFSICEGNIIMIFIDSTL
ETNHERWAGYMDEVQLQWLKNEIIHSTGKTIFIFSHHPVYGTTTFSKDENSYIEQIEELN
KILALHEGRGIFFCGHNHANSISKRDNWHFVQTAATF
>A0A3B0Y052|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MTTDPVLRIAQITDTHLYADPDAQLLGLNTRHCLQQVVNLARGRNPDLIVASGDLSHDGS
EQAYTLMQACFDPMRIPVHCLPGNHDEAAMLKTRMSGNGYHCHTGFQSNGWQLIFLDSTI
TGSEGGHLSDDELQGLENRLKQASDSPTLVWLHHQPINIGSCWLDTMAVDNPDDFFAIID
RHPQVRGIIWGHVHQVFEQRRNNVQLLSTPSSCIQFLPGSKDFAVEHIPPGYRWLELYAD
GHFNTGVERLPNIPGNIDQSTRGY
>A0A238J685|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Boseongicola aestuarii|TrEMBL
MLIAHTSDFHIFADAPETSLVRPDIVQATRKVIADIANFSPCIDAVMITGDLADGGSAED
YVLVKDILSPIKVPIFAVPGNHDARQGFRAAFEDSLPFGPGSKLDYEASCGDLRIIALDT
LIEGQVTGGLDDSQIDWLAERLASPTERLTLILMHHPAFPSTITKLDQMALKDGHSKFEK
LIAQYSGPVRILSGHIHRPYQTLWNGIWCAVSGGPSFQHALKLAHNAPEPSDVDEPFAYF
IHRIEEAAAMTVHTRYVAL
>A0A1V5CSE5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Syntrophorhabdus sp. PtaU1.Bin002|TrEMBL
MKPVSNTRVIVVLVVLLLFFPLLGYSADHRSFAIIGDTGIGVNDLHYRTFLQKIESEGID
LIVHTGDVIDKPGSQGEWKRFLEITGNKPTVLISLGNHDINTVKSLKVYENLTGRTPYFT
FAMNDTQVIVLCTELPGEWSRITGKQLAWLSAELAKPFRYRFVFLHRPLFPAIYYMGASL
DKFEQDRNLLHALFIRHHVNMVVAGHEHLYNRTIRDGIAYVISGGGGARLHAFTEEQGGF
FHYVIAKRNKEGYVLRVYDFEGKVRDEFEIKNEVRNG
>A0A8C7XYH1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oryzias sinensis|TrEMBL
SPLIKKKSKNKNPKEQERSLEQMDRGVVDLQELRRNLELASAMLDAVYTDETRRLLDTED
ELSDLQVESVPSEVRDWLACTFSRRTGLSKRRPEEKPRFRSIVHAVQAGIFVERMYRRTS
NMAGLTYPPTALNALKEVDQWSFDVFTFHDATGEHALKFIVYDLLTRYDLINRFRIPVQA
LVQFVEALESGYSKHRNPYHNLIHAADVTQTAHFLMLHTGLMHWLSELEILAMVFAAAIH
DFEHTGTTNNFHIHTRSEVAILYNDRSVLENHHVSAAYKLMAEEDMNILVNLNKDDWREL
RSLVIEMVMSTDMSCHFQQIKTMRNSLTQTDSIDKVKVLSLMLHAADISHPAKAWPLHYH
WTHSLMEEFFRQVPDRNAKFGEDKSSLYIADR
>A0A518CKE5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Polystyrenella longa|TrEMBL
MNHNRRSFLKNGSLFLLGSQMISKSDLLFGAVSPTVSERTHRIALVTDMHYADKEAAGSR
HYRESLDKFDEAAAKYKELKPDFLVELGDIVDAADAVDVELGYLKTINAKLSQVADERHY
VLGNHCVYTLTKEEFLGEVGKEKSYYSFDNKDRHFIILDACFRPDGVPYGRKNYDWTSPF
IPAAELEWLEADLAATDKPTVVFTHQRLDVDNHYGANNSPAVRKVLEESGKVQAVFQGHS
HKNEHVELNGIHYCVLAAMIEGSGAENNSYSTLEIFNDGTLKLNGFRKQKPYQWS
>A0A517WK45|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia chilikensis|TrEMBL
MPVHLPAQNRRQFLFTLGAGFLTYSAGAFAKDSQQSDIIYLLNDTHIGEKHPENSPVPSH
LRKVVSELVSLEQKPACVLINGDLALRDGQPGDYRHLAKLIRPLQEAKIDMHLTLGNHDE
RDVFYSVMQEEQPETPPVKSKHISVVQTPHANFFLLDSLHKTMVTQGTLGAEQRTWLAKA
LDAHADKPAIIMTHHNPRLGGDPNHFPGGLTDSVELWEVLAPRKQVKAYIHGHIHHRSNA
EHKGIHIINTPATSYVGNPKASTTGWTIAKLSPTGITLTTRTTDDQHPWNHQSQTLTWR
>K8AD76|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cronobacter condimenti 1330|TrEMBL
MLIAQLSDIHAAPDNLNLTRLDNALTWLTPLNPDVLVLSGDLIDNGWYEGYQRIAERLAT
FNCRIIILPGNADDRGAMRAVWGPSMWPEAPDNGPLHAVVDTPALRIIGLDSTLEVARRA
ALTHIFHGFHSSLTVPADGRRCSFYTITFLKVAFRQWMR
>A0A0V0RY76|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Trichinella nelsoni|TrEMBL
MRQHGIVQQVQLSQQIQEISRDLNIISNNSNANIFFNATVINVDKYLHTKQTIPMVKFEA
FLNKLQQGYSKHNNPYHNLVHAADVTQTAHWLLAQSGLVECLTDLELFAYLFAAMVHDFE
HTGHTNNYHVQSSSDYALIYNDRSVLENHHVSAIFRLMHDSSQYNILEKLTKEEIRQFRN
LVIEIVLCTDMSTHFAQVKDVKQMITSDEEIDKTKALSFLIHCSDISHPAKIWPFHFRWT
EQLMEEFFRQGDLEMAMGNPISPLCDRLTVNIADSQIAFIDFIVEPTMIICSELLAKLLE
PVLQAFDSGSGERPKQLNSIDDFRMSQPWMKIIPENRMKWKEYIAQQNKLPE
>A0A151B2C5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium tepidiprofundi DSM 19306|TrEMBL
MALWAISDLHLALNMNKPMDIFGDNWYKHEEKIEKNWINSVSHEDTVLIAGDISWSMKME
DGMIDLEWIHNLPGEKILIRGNHDYWWHSITKLNNLYDDMHFIQNNFFNYNDYAICGTRG
WICPGSANFSEHDRKIYNREINRLRLSLDSAVNNGYSKIIVMMHYPPTNDKLENTEFIDV
FNEYKVKKVIYGHLHGPSLNNLFEGIHSNIEYIVTSADYLDFKPKLICLDDIVIKP
>A0A162RM90|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium magnum DSM 2767|TrEMBL
MSLYAISDLHLDLNGDKPMDIFGDKWFKHDEKIKNNWLNKITDKDTVLIAGDISWSMKIE
SGIKDLEWVHNLPGTKIMTKGNHDFWWSSISKLNNLHEDMKFIQNNFFIYEDYAICGTRG
WTCPGGENFTQKDEKIYTRELNRLRLSLDAAAKNGFKKFIVMLHYPPMNEKLLESGFVQI
FKEYNVEKVVYGHLHGPSLAKALNGVLDNIEYIITSGDYLDFNPIKIL
>A0A2N7RCP6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Janthinobacterium sp. AD80|TrEMBL
MSEGRQAYCEVELAGERLWLLADKAVYWPARKMLIIADIHFGKAAAFRALGVPVPRGTTT
QNLLALDALLATYACDAIIFLGDFLHARAAHAAATVAAMLAWRARHPHLLLTVVRGNHDA
HAGDPAAALDMRMADEPHQVGTLAFCHHPDTPAAGYVLAGHVHPVFHLRAARGGLRLPCF
LLGPGRAILPSFGAFTGGHAVQPAVDERVYVTADAAIFAIPR
>A0A177B1K2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Intoshia linei|TrEMBL
MGVPVSHYTTPNGKIKCEIRADHLERLNQQSIYRKHLKKENWLEVKKFKEELGEFVFSNT
HCIKQLHELSERIKSIINFIEKKKKVNKQLILENFKLASQMLDMAHKNEKKRIFNIIDYK
GRDNQKLPQEVKRWLYTTFHKNTQSNIKPEIKRFRCIVNVIRFGHIISNIQKKSILYNIP
TLVRSDIQNSHLWNYDIFQLDSMCNGNTLRFLSGYLLNTFDVFNIFKIPLIVFENFIIKI
QEGYSKYDNPYHNNMHASDVTQTVYSIITYCSNYSIYLSSTEIFALIFSAIIHDHEHTGT
NNSFHVSTRSELAILYNDASVLENHHIASAFKILQDKDCNILYNMTAEQYRKFRSLTITL
VLATDMAFHFEQIKNITEMLEFKDEYTLLIKINVNVNVNDTLDFNLI
>A0A5P9PQN8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Amycolatopsis sp. YIM 10|TrEMBL
MIVIAHLSDLHLDGDERSLARATRVFDHLNGLRGEIDAVLVTGDLADHGLAEEYEAVAKL
FAGPRKILQPLHCPGNHDVRGPYREVLLGEAPSDGPINQVHHAGGAVFALCDSTIPGRDD
GYLTDETLAWLESVLADAADAPVFVCFHHPPAELHIPYVDGIRQTGEDRLAALLSRRSNV
VAVLCGHAHTAAAGTFAGLPLLVAPGVVSTIGLPWESDRIIDLDAPPAIAFHVLGDDGRL
TTHYRVIQAPAR
>A0A6G5ABB5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhipicephalus microplus|TrEMBL
EVREWLASTFTRQAATQRKRSEDKPRFRSVANAIRAGIMVEKIYRRLSSSTLLQIPNHLA
ALLKSVDDWCFDVFNVNEVANGQILRYLTYELFGRYGIVHKFKISSAALENFITAVEQGY
CKSXXXXHNNLHAADVTQTVHYMLYSAGIGNWLTELEAFATLFAAIIHDYEHTGTTNNFH
VMSRSETALIYNDRSVLENHHISAAFRLLTDDDQNILSSLSKEEYKEFRLLVIEMVLATD
MTSHFQQVKTMKTALSHHDFSLDKAKALSLILHCCDISHPSKEWRLHHRWTYLLMEEFFQ
QGDKEHELGLPYSPLCDRNTTLIAESQIDAEARENEQAKQMKHWSLIGSRPCRWSQAC
>A0A0R3RMW8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Elaeophora elaphi|TrEMBL
MDLISRWFDAIEAHYHSVNPYHNATHAADVLQATSFFLDSPTVAHYVQEAHATAALIAAA
VHDLDHPGRGNAFLINTRQPLALLYNDQSVLENHHIALAFQLTLQSTNNINIFDGLTREE
FTTLRQATVEMVLATDMSRHFEYLTKFQQVVANLKENEENENNISLTICRMLIKCADIGN
PTREWELCERWAMRIVEEYFDQI
>A0A240CD85|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serratia ficaria|TrEMBL
MPHGELSEYQLEWMERCLQAHPERYTLLLLHHHPLPSGCTWLDQHSLRNPHMLGAILLRY
PKVNTLVCGHIHQDLDLEWQGRRLLATPSTCVQFKPHCTNFTIDEVSPGWRYLDLLPDGR
VETQVFRLENDDFRPDMDSDGY
>A0A381KRJ4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chromobacterium violaceum|TrEMBL
MRIAQLTDLHLFADRQGRLLGRDTHAALDRVLAALRTAEGVEAVLLTGDVSQDESEASYH
LAAEALAALGVPVHWIAGNHDDRAAMARVFAGYAFLRPLETLALGGWTFIGVDSCVAGQD
GGRLSDAGLDWLRRLLDEAGDGPAAVVLHHHPLAVGTPLLDDCMLAPASPFWRIAAASAA
LKLAICGHVHGEHSIAYRGKMLEVGPATCFQWRRDACDIEIDDRHGYRLFDFDGDGYSVR
TVFV
>A0A1Y0HLI4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sulfurospirillum sp. SL2-1|TrEMBL
MNHKIHHLSHTDLDGYGCQMVSAHYFNSIAFYNSNYGKEINECFNQILNNIQTSSLQKHV
ILITDLNLTMDQAKEFESKVSICDKEIMLFVLDHHKTGQECADAFEWYFLDSSRCATKIT
YDFFSALYGKNAKLSKFVDVVNAVDIWLENEPEFELGKVCMGLVSGAKEVNKVMFPEENS
HYIFSLLTKAQEYFTCKDAHIALDDAIHNIKKQFFVTSTNNTLSNLVSAYNVILLTKNRE
RMQIMYKEYKGILTYNIGNVSVIGNDFLTANPDLDFFMDITSKKTISLRSNGKVDVSKIA
AQIANGGGHHNASGGLLSNFKDAFIYDTIKSQVMSIIANKG
>A0A1V4IPE4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium oryzae|TrEMBL
MKRKYIIVLVCACIFIFMDILVFHINMDTLKLTSSNKRDAAILPKAVSIDENSLHMLLEK
DDKVNELILKLQGVEKMGNIKFYINRHVTVDGRKVLNGNPYLVFECKKCSLGFRNSININ
SKLVNVFNIKTSRYKTLKIPIDYKLFNYNLKNIISINSGVREDESYNNKNKKMDNFYVRN
VRLILNDGTLIRDEKYQDSTIALGSGKKRKKKIYLNFNIPKEKFTSTIAVIKYDSLRQGK
NNIKVLTSDTVLKEKFLFDSEPPAIKPNFKNNVVYKDRVKINFTVKDKVSKVKLVNVKLD
NREISIPYEDLASRLKPGKHIVKVIAADSQGNQVTEYFCFTTSRENYDVNIKTNNNIKDV
IVGKSPLEKYNVYVYEGEKCSGRSIDVYGAANRLEPMVLANKNERQFLSENQKLIEKVDG
KLLKMKSKYNLPYEKFDIKIKAGNLNSKIKIVWKGYVESSQRLTMYAWNVCKNKWVPLKS
TLADGKNAEITASVTANNYVDQNCIHVIVQSGNTAVLEEKCNDFTFAWMSDTQYYSKKYS
DIYKSITDWLAENRKKIKYVIHSGDLVDNYNDINQWTIADNCMKVLERYNIPYGVLPGNH
DVNHEKGNLKYYCNYFGAKRFKESPVFGGAYRNNKGHYDLISAGGNDFIVMYMGWEVQED
EIRWMNKVLSKNREKKAILVFHEYMFEYGSRTPTGNTIFKNVVIPNPNVLAVLCGHFHES
RMLVDEIDDDEDGETDRRVYQILADYQDGPRGGEGFIRLLKFNCKSNTIDVCTYSPYLRK
VNFYDKQKYPLKDTFTIDMDLKPLEKAVATDYFGAAVYTNKKLCEYRNVTGGNIIHIDGS
KISEKYDGYFIVTEDSSGKKSVTDVYNN
>A0A1R4G730|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Frigoribacterium sp. JB110|TrEMBL
MSRATGRLTVLHVSDVHATRDGLLYDRIDGIERLRAVGSYAREAGITPEAIVITGDLIQR
GHAAAYPRVQAAIDDLEQAAGVPVLTVLGNHDDPGAAGALRDHAAGHFRTVHVAGLRFVL
LDSSAGALGAEQLAWLRDQVREPFGAGTVVALHHPPLGSPMPALAKAGLADGQCLLDALA
DSDVRAVLAGHFHHPLSATLRGVPISVGPALAYHQVMNAGPDRVSGHDQAMFSLVHLLPG
GVAATSVSLETPAPLFSQPVSA
>A0A8C9FEZ2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pavo cristatus|TrEMBL
ILLVCQPSKRGFIRRLLDTEDELSDIQSDSVPSEVRDWLASTFTRQMGMMLKRTEEKPRF
RSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIGVLKNVDKWSFDVFALNDASGDHALKF
IFYELLTRYDLINRFKLPQTFDREVSNNVVEKYRLDRCVWFLCFFFLASLIVMPFKREFR
ALVIEMVLATDMSCHFQQIKAMKNALQQPEGIDKPKALSLLLHTADISHPAKAWDLHHRW
TMSLLEEFFRQVKSHPGPSGPTCAGTSTAGFIDFIVEPTFTVLTDMTEKIVTPLIDEASR
SGMSGFRRSSTTAHLSTGSEGSASLNCSILTVDFKCFKATWTEVVQQNREKWKAQATKGN
IQAS
>A0A1D7ZWC9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Limosilactobacillus fermentum|TrEMBL
MTERIKIFSHNDLDGFGAPYLLQAVQETVFPDTTFDIDNIGAGRIDEYFDRWLHSPEAGS
FTDVYIMDMTPDSEHTFQELNANFANHWLVFDHHESEAEARQKHAANVVTQADADVNPSA
ASLAWDWLTTQPRFDQLSADRRRDLAYLIELIRAYDTWDWQNDPNMSQEVRVAADEFDQL
FWFYPLSHSAEFVEQVFAQGWEQYRQQNDLLVQTLNDRRDHYLKGHLKDLMIEEIAGHKW
GIVYASDYKSEIAHRLMEENPEVDAAMVVAPTSVSLRSNGKVDVAQFAEQHFRGGGHADA
AGGRLDVNLIQVGEQAVIDFVKEKIANQAEEAKEEETTLADSLDPELAAKMAALFKK
>A0A292YT28|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudonocardia sp. N23|TrEMBL
MLDPDVVPALAFHVVDGHRLTTHYRVVPRLTTPRSDTARIRSQVELGAERTA
>A0A0W0TBP8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Legionella drozanskii LLAP-1|TrEMBL
MENDFSLKESLKILQITDTHLFSTNPNLFGINPNKNFNEVMRVVFNHELQDTDFILLTGD
LSQDETANSYQYLVESFKHCKKPVFWISGNHDNEKLMAEVFSPFALFNRGKFLELKHWIF
LFLNSKLEGSENGYLHQDELNKLEKQLKLCHKNVALIMHHHPTPVNTPLIDKYILNNRDE
LWEIISNTKVKLIITGHVHGDYSLSKNDIKVECSPATCYQLKKGTSTLEIDKAIGYKIHY
FDNGRYYSKAVEWQFP
>A0A4W4HRU3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Electrophorus electricus|TrEMBL
LIFQSLDMEDQLQELRPDSVPKEVHNWLASTFMQQARRPLRYPDYKPSFRSIVHAVQAGI
FHDLLTLFTELMIRYELNSRFKVPISCLMSFLCELEQGYNKHNNPYHCQTHAADVTQTLH
CLLLRTGLVHWLTELEVLASLFAAAIHDNEHTGNTNSFHILTRSDLAITYNDRSVQESHH
LSSTFCILQNEQMNIFTNLSREEWVELRSLVIEMVLATDMSFHILQVKAMKHSLQQQERV
DKAKALSFLLHTADISHPAKPWVLHSRWSKALTDELFRQGDKEGELGLTISPLCDRNTAP
VAQSQIGFIDFIVDPTFSLLMDMAEKIIIPLVQDNPEPPEPINRHRLQQFIIKLQTSNTS
GQQRYDGSPDHCKNLLSQFSMYSPPPXXXXXXXXXXSLRRHGNRVITVDRRGRGMGNRSL
GQPGPSIAV
>A0A3M3XZN4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas fluorescens|TrEMBL
MNRPFLVAQISDLHLKAGNRLTYGVVDTLGALRRAVDHLNASDPRPDIVVVSGDLVDFGR
ADEYAVLRPELARLQMPCYLVPGNHDSRAPLLDAFRDHAYLPASAEGPLDWVVDEHPLRL
IGLDSTIPGGHGGQLLDSQLQWLDEQLALRPAAPTLLILHHPPFVSGIGHMDREAFINAS
ALERVVARHPHVERLLCGHLHRPMQRRFGGSVSCVCPGTSHQIVLDLQDAAPAHFNLEPA
GYLLHRWDEQQGLISHNGVFGDYPGPYPFYDAHGLID
>A0A0A1DMT9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nocardioides simplex|TrEMBL
MEPLGQYPDPTHVVAHLSDPHLLADRLLYDAVDTAAHLERALARLRRLPTPPQALVFTGD
LADRAEPGAYARLRAIVEPVADELGAEVVWVMGNHDERRAFGQALLGTDDDAPRDRVHDV
AGLRIVALDTSVPGWHHGELSDEQLAWLADVLATPAPHGTLLAMHHPPIPVPMLRLAELI
ELHDQERLAAVVRGSDVRGILGGHFHFTSYSTFAGVPVSVASATCYTSEVAPEARMVAGV
DGHQAFTMLHLYDDRVVHSVVPATDATEVTGRGEELLEAFLALTPAERFDLVARKDSPLN
VEPT
>A0A085U491|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Yersinia ruckeri|TrEMBL
MFNKGLALIFSLYSSLSWGGFEVVALGVDGGVSDGNLTSYLIRGDNNPLYLALDAGSLLP
GISKALDNGHFADVTDQMAAPFTRQGYILRQRINSYFISHAHLDHVAGLIIASPEDSKKT
LYGTASTVETLRNYYFNWRVWPNFTDSGSGTRLGTYRLEAKRPAQSFTIGLTRLLGEIYP
LSHDQSPSSMLLISQNNESFAYFGDTGSDAVENSKNLDQIWRILGEKVKQQQLKGIIIEV
SYPNNVADGKLYGHLTPKWLLTELKNLAKYSGESKQPLKDLPVVISHIKPSLQQGVNSRQ
IIADELQQGNDLGVKFIFMDQGERQQF
>A0A078BGC1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thiomonas sp. CB2|TrEMBL
MKLIHLTDTHLTTPGRSLYGIDPLARLQAAVEHIAHQHADAELCVVTGDLTHWGEAAAYA
SLRDGLELLPMPVLPLIGNHDHRGRFRAAFPEVPVDENGFVQWTHDTSVGRFILLDTVLG
DADQRRPSAGYFDAGRVEWLRAQLDRAQADAAPVFLFMHHPPFGVGIAAFDEINLVADDA
LAFGALLREYGHIRHLFFGHIHRPISGSWHGIPFSTLPATAHQSGLDFLTETDLFTHEAP
GYGVVLITPEQVTVHISDFLYRGPQIDPGSERLHG
>A0A853STX7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Janthinobacterium sp. HH102|TrEMBL
MRTIVHLSDLHFGRVDGDLLAPLRALVERLEPDVVVVSGDLTQRARSAQFQAARHFLDSL
PGPQIVVPGNHDVPLYNVFSRFLTPLVKYRRHVTDDLSPEYVDEEIAVLGINTARSLTFK
DGRISHEQIDFLRERLGRLPPGLTRIIVTHHPFDLPEHFDEDDLVDRAPQALQMFSECGV
DLLLAGHLHASVAGNTAERYKIAGYAALMVQAGTATSTRGRGESNSFNVLRVENSCIRVE
RYSWNEDSAEFEKVSTEAFERQGGVWASLRPL
>A0A3N9CPP5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Burkholderia cenocepacia|TrEMBL
MLLAQISDLHIKRPGQLAYRRVDTAAALARCVEKLNALVPRPDAVLVTGDLTDFGHDEEY
GNLRGLLAALEIPYYLMIGNHDDRAGLRRAFADRAELQDGEFVQYALDVGAVRVLALDSQ
VPGASHGDLCDARLAWLAAQLDAARDRPVIVALHHPPFVSGIGHMDKLRLAPAAAAKLDA
LLRGHPNVERVLCGHVHRTMFTRFGGTLAAAVPSPAHQVAFDLRTDAPSAFRLEPPAFAV
HHHAPDTGMTSHHVYVDEGAGPYPFYEPTGELVD
>A8HRY6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chlamydomonas reinhardtii|TrEMBL
VLAGVDSWTFDAWKLAEVTQGHALSALAFYLMHREGLIAKFQIKPAVLARLLRALEAGYQ
PNPYHNATHAADVLQTLHVVIHGAGLHVHYLDRLGLLAAYFAAIVHDHNHPGLTNDFLIT
TNDMLAIRYNDKSPLENHHTASCFGLMALQPELDALAPLSQTEKSGFRKQVIEMVMGTDM
KQHFGIMAHFNTLVCSETAPKPLDDKERMLSLQIALKVADIGHLGESLAVHKRWLAGLEE
EFFNQGDRERDLGIPISPLFDRAKQGVSKSQVGFYDFVGLPLV
>A0A088RWD6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Leishmania panamensis|TrEMBL
MSLMPGHPVPRSQWVESAEVCAACGKRFSFFTSKENCPCCGRLFCSSCLSAQCTLFPMAA
PKAVCLDCFRKTQDWRLSQLEQHAALTPADVGAASLPLSTSTEALELKLKALDEEFDRTK
ADTRRLREENDTLIDLLTAKDTCIAELTEELMKAVASADAAAQSAEKLQLQLRDQRESTA
RQLEEAEQRAASAAQASEAMNAQIQEHMQAKVEWEASAVKLQSAVRKAEDMSVQSAEELR
ELRAAMKTMNTYSEEKIKQLTAQLQSIVEASTHLQKDYDRNVESLRAAEQSRIASDAAHD
KELQRLREDLSKATSALAQAQERYERQQISAPKFTDDAAAVDGVEKQREIATLKEQLASS
SAAQRHLQGELDRAVEEALRLREDGALKAEAARALVSELRTQLNAQRTAVQQDLPWEQEA
NARLRADLAEKEQLVTKLRRGCFEAATAVRAELGDLRGKLVETKLSYEEGLRSWQTWLNE
LRAAVEAALQQQALISAAASPSDIAALPHVPAATKSRWAQDTIVEELQYVSVSNVNVGTI
APVPGLEKWEFDTVAEAQRGGEADVLMRIGHQIALNLNLFPDRASQHRWVCLLATVQANY
RANPYHNRVHAADVMQGVYALICRCPGLLAHMTTVEKRAVVFAAAVHDIRHPGRSEMFLR
NTFDAMYMRYNASQVLEQMHTATAFHLLATPELDFTHGDMSDTEALEFHGLVAALIGCTF
MGLHASLMEQWSRPLQEGKAYDVTVAADRQQALSLFLHAADIGAQARGLAVAPKWLGIVE
EMRAQGDEEAARGLPPSPGSSRSASLERGQLFFMEMFVVPLFDLVHQVFPSIESPMRNLR
TLHAHYCAALQETREFPPSVQYRIATKPVSNTVETTRTEALDAREAALKKREKALKQATQ
RLREATATVADRERQVGEKEAAVMRAETSVSTHRNERRSVPSSIDEEKLLRATTAVIARE
ARVERGVANVEKMTAALEEREAIASRLTEQLATIAEKVNQRRQLLRYREARVRGLEATLR
AERLGNVSSEDYITGLASCPLVKPVTTATRFDRVSPPAVVVVKLESALEKLTSALRYM
>A0A2X2W303|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Citrobacter koseri|TrEMBL
MLLDSQVFGVPHGELSDFQLEWLERKLADAPERHTLLLLHHHPLPSGCSWLDQHSLRNAA
ELDSVLANYPRVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPALRELHAGHDRARLA
DAGTVRRGFSGNASASSAGDSIPTRYRFGRILMSTLLYLHGFNSSPRSAKACQLKSWLAE
RHPHVEMIVPQLPPYPADAAELLESIVLEHGGAPLGVVGSSLGGYYATWLSQCFMLPAVV
VNPAVRPFELLTDYLGQNENPYTGQQYVLESRHIYDLKVMQIDPLEAPDLIWLLQQTGDE
VLDYRQAVAYYASCRQTVIEGGNHAFTGFEDYFNQIVDFLGLHSF
>A0A2X1Y6J7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Photobacterium damselae|TrEMBL
MTFQSGSNMTFLNGTYKVLARYPAKVKSVLCGHIHQELDCMRQGVRVLATPSTCIQFLPD
SDDFALDSKAPGWRYLELTPQGDVHTQIHRLANDQFAPDLNSAGY
>C1AX97|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodococcus opacus (strain B4)|TrEMBL
MSGTEAADIRTAEYPRPSHVVLHLSDTHLVDDDLLYGAVDSEATLRQIVTEIEASHARPD
ALVFTGDLTDRGQPGAYEKLREIVEPVAATLGAQVIWAMGNHDDRGHFRAELLGQEPTYE
PVDHVHDVDGLRIITLDTTVPGHHHGEISESQLIWLAQQLAIPAPHGSILALHHPPVPCV
LDLAVLVELRDQPRLADVLRGSDVRSILAGHLHYSTTATFAGIPVSVASATCYTQDLNVP
AGALRGRDGAQGYNLVHVYPETVVHSVVPIGSYDTVGEYVTAEETARRLVAEGVRIPDGE
AAVAPADRDQLVRGNFSR
>A0A212JP71|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured delta proteobacterium|TrEMBL
MLVIQISDLHVAANRGLAFNVADGAALLEKTVDHLTALPQKPDCVVVSGDIAVNGTPGGY
AIVAEQFARFDVPVFVLPGNHDNRENLLAALGRYCPADPKMAPYLCYTREEFPVRLVFAD
GTRPGSHSGHLDEQVAEWLQTVFCEKTDTPTLLFTHHPPFLSALGVMDEPYENAGAFGAI
LDENPQVRLCCGHLHRSMATLWHGVMAMTAPPLALHIVADFSPQGGDAFTDGTPAYLAHH
LYEGRVNTHVCQVPGTFAYKGPYSFAKPPKLS
>A0A517VLJ0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia algae|TrEMBL
MKQESQSPVESLTRRAFLKNGALILSGLTLSPWSRTALGDLDTTKRGAVRIGLVTDLHYA
DKPPVGSRYYRETLTKLKEAATQFDSDRPDFVVFQGDLIDSGKSLEQEKTHLQTVVNAIS
AIPFPKYYVLGNHCVDQLKKAEFLQGVGQKKSFYSFDQNGFHFVVLDSCFKSDGTPYGRK
NFTWTDANIPPEELAWLQADLKQTAYPAIVFAHQPLDLKDTDSHAVKNSSEVRKVLEQSG
KVTAVFQGHSHRNKYSEIKGIHYCTMVAMVEGSGLDNNGYSTLDVYEDGSLILNGFRKQK
DYRWS
>A0A485ARP8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Raoultella planticola|TrEMBL
MLLAQISDTHFRSHGQKLYGFIDVNAANADVVSQLNALTERPDAVVVSGDIVNCGPPAGV
RGCPADPRQPELSAVSDPRQPRR
>K8BAT2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cronobacter dublinensis 582|TrEMBL
MLIAQISDIHAAPDNDNLARFDNALAWLAPLAPDLLVISGDLADDGWRDGYSQIAARLEA
FSCRLLILPGNADHHDALRATWGATLWTGADGPLHKVVDLPGLRVIGLDTTLEACAAGSV
AAHLDWLSQQLDEAQGRQTLLFMHHHVFTSGIPSMDAIMCRDHDALAALLRQHPARPLAI
ATGHVHRPAAGTLAGIPAYICGSVCPANPLWLGASHVPCVYDPPALMVHRVDNGALASHF
IAVSPVTAA
>A0A2N9CFK4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Burkholderia cenocepacia|TrEMBL
MLLAQISDLHIKRPGQLAYRRVDTAAALARCIAKLNALVPRPDAVLVTGDLTDFGHDDEY
GNLRGLLAALKIPYYLMIGNHDDRAGLRRAFADRAELQDGEFVQYALDVGAVRVLALDSQ
VPGASHGDLCDARLAWLAAQLDAARERPVIVALHHPPFVSGIGHMDKLRLAPAAAAKLDA
LLRGHPNVERVLCGHVHRTMFTRFGGTLASAVPSPAHQVAFDLRADGPSAFRLEPPAFAV
HHHAPDTGMTSHHVYVDEGAGPYPFYEPTGELVD
>A0A0N5AZB7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Syphacia muris|TrEMBL
LLKFQEENVPSTSASNSPKLTFVEKAKLSAISHISGVQKIRSPFGGKIPQYGVECNKGIA
EHIKKLDEWGPDIFEINRLSRGHSLTTVTYNILKNRGLLKVFNIQPGPMINYLLVLEHHY
RDNPYHNQIHAADVTQSMNVLISSPALQGLFSDLEILSAIFASAIHDVDHPGFTNQYLIN
SNSELAIMYNDESVLEQHHLAVAFKLLQDSSCDFLANLTKKQRKLLRKMTIDMVLATDMS
KHMSLLADLKTMVEAKKVAGSSVLTLEKYPDRIQVLQSMIHLADLSNPTKPIDLYRSWNQ
RIMEEYWRQGDREKDLGLELSPMCDRYNVTLEKSQVGFIDFIVHPIFETWADLVVPHAQH
ILDQLEINREWYQERIPEEQQDARNDNESNTQDDGNTSEDT
>A0A086QXD5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii MAS|TrEMBL
LSLSIQVHVGFSLDLRGYRWVSLSSLRLRFCGRCFLCPADGSDDEPVELFPLHNETLQPL
FPGGDQIPEPLLFDVNSVVQAVNQVGLSRPAEQLAAAIAQTPFQKDLDASAKFIDALDSS
LALLRYYQTLPGRDGSLQKRRRSRRMTDLDPQGTDRTWRPESKRKDPLAMMQSLSALQVK
VPAEPEVQAFFNLASCTLSVEDPISIHQVLNWDFHVLNLTPSTATRIAR
>A0A446ZP66|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acinetobacter calcoaceticus|TrEMBL
MTFQVSTLSQKDHVIIQITDTHLLEYPHLEFVGMNPEESFHAIIQQILKKHPETDAIIHT
GDLAQAPTPITYKRYIQYMQTLGLPFFQTLGNHDNVDHFPLHKENHQEPVVICLGNWRVI
LLNSAVKGQIDGHLSPEQLQNLATLLEEFSDNPILLACHHHPFAMKSKWIDHHKLQNSNA
LLTTLAPFKNVKALVCGHVHQDSLNTWQGIEFFSTPSTSVQFKPFSNEFALDQNAPGYRY
IRLKNDGSFETEVFRLENFQGLINTDISGY
>A0A2N9B4N4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces chartreusis NRRL 3882|TrEMBL
MLVLAHISDLHLDGSERATERAERVCERLRELPGQVDALLVTGDIADHGTEPEYEEAARI
LGLRDGDAPFPVLACPGNHDSRAPYRKALLGLPGAEEPVNSVQVFDDGAVLMCDSSVPGS
DDGELDEETYDWIETTLDELDGGLPALLAFHHPPVALHHPLPDSYQLRESGRLAGLLARR
PEIAGLITGHAHTPAATSFAGRPLVVGPGVTWTLRLPWEGEQIADRDAPPGIAFHVLDDT
GRLTSHFRVVT
>A0A0M3IWB7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ascaris lumbricoides|TrEMBL
IAPEDILRFTVRDIPASTSFHADFTQFFFVPRSIGTGDTYIEASLSMFKELGFIERFRLR
RRTLARFLLMVQKGYRDVPYHNWSHAFAVGHFCYLLVRTAAVRSALTELERLSLFVACLC
HDIDHRGTTNAFQLQSKTPLAQLYSSEGSVLERHHFAQTVSILSMXQKLQ
>A0A482ZEY8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured SUP05 cluster bacterium|TrEMBL
MKRLLQISDCHIDDVEQSIGVNSHQNLSLVVNEITQLEADALLISGDLSHYGSLNSYKKL
KQLLAPIDTDLFVIAGNHDDKNNLSAVFNENLFTLFTLGKWDIISVDSVQAGQTSGYLTK
QVLLDLEARLTQSTAEYILLVLHHPIVSMQSTWDDTLSLENPQDLFAILTKHPNIQAVLF
GHAHQSAEFKKNGLRIIACPSTAVQFNDESRIGFNYYRLYDEGKFDCEVKWIAS
>A0A483AA06|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured SUP05 cluster bacterium|TrEMBL
MIKLIQISDCHIDDQAVVMGVDTQANLKKIVKELDDCKFEALLISGDLTHNGTANSYTYL
KEILSPIEVPIHVIAGNHDNVVKLNIAFKDNLFSCVEFGNWEMISINSVQPEKTSGLVTS
KALAELDQRFLNSNADHILVVLHHPIVAMNSSWDDSLSLENPQDLFQVLDKHSKIRCVVF
GHAHESADFYHQNCLIVSCPSTALQFNQESRIGFNEFTLHDDGQINWTTQWI
>A0A081G2C6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Marinobacterium sp. AK27|TrEMBL
MAESTARYLLQISDCHLMPDAGQRFRGLDTDETLRAVVAHAKGLDIDFDHVLLSGDLVHH
GAPDAYRRLLQIVSPLPGSQHWIPGNHDERAAMRAASERPLGRELVRCGAWDLLLLDSTD
APDGRGSGSLSASELEWLDQTLAHSHERPALIVLHHNPVVTGSAWQDPIMLGNADAFARI
VDRHARVRGIICGHLHQHQALRLGQVPVWSAPSTGIQFKPGQRDFMLEDDPVAACPGYCV
YRLSEEGGIEASVHRVEAR
>A0A3B0JE43|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Arsenophonus endosymbiont of Aleurodicus floccissimus|TrEMBL
MENKIAAVNSTYSIFVISYPQAWCLALADNDPNDDRSRWHSKLNPVRNSIVSLNNSLHVP
FGMINGELTEYGRRSQRESYRKFFSPNALNFYVYVGLGNHDYQNNVGNCSESSNSDYSMN
ACAKGMVFDMHYRIEEYRHYPTSINFSYGSGEYSGSKAYSWDYGDIHYVQLQNYPTYHVV
LDHWAAQIIKVTQSMDWLESDLKSAKQRGKTIVLNIHDGTDHFIHQSSTEEKNRFRRFMS
DYNVKAVFVGHTHQVAQENPYGNHELFGNFKVYNSGHYLKVIF
>A0A0V0YAV9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Trichinella pseudospiralis|TrEMBL
LYCRRHHRLAVAGPAITDPLASQQNFQLMDHSSQFYFLTLRKHACRLRYIIYQMHRGEMS
SKDLIDNLEYAASILESTYVDSCRLQVEEQIDQIDSEDVPEESVNEQHQKVSFKSVANAI
RSGIRFDSKHNNPYHNLVHAADVTQTAHWLLAQSGLVECLTDLELFAYLFAAMVHDFEHT
GHTNNYHVQSSSDYALIYNDRSVLENHHVSAIFRLMHDSSQYNILEKLTKEEIRIDKTKA
LSFLIHCSDISHPAKIWPFHFRWTEQLMEEFFRQGDLEMAMGNPISPLCDRLTVNIADSQ
IAFIDFIVEPTMIICSELLAKLLEPVLQAFDSGSGERPKQLNSIDDFRMSQPWMKIIPEN
RMKWKEYIAQQNKLPE
>A0A0P7YJ13|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Erythrobacteraceae bacterium HL-111|TrEMBL
MTTTLFHVSDIHFGSENRAALAAVEQAIARERPDALVCTGDLTQRAKHREYEAAARWFDS
LGLPVLVDPGNHDLPYYNLWERFTDPHRRYRRLRAALGRSFESRDVVLVPLNTTVRAQRR
FPWSDGVVTRRALEETLAALKRLEGDPRCVIVTAHHPLLGPENGARNPTIGGDAAFAALA
AAGAVAVLSGHVHVPFDEWRERAGQRLRMIGAGTLSTRLRGGVPPSYRVLRCERGGRIEC
ELRVAAGAIPGSDAPPAALAS
>A0A1L1PTA5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Hydrogenophaga intermedia|TrEMBL
MLIAQVSDLHVCAPGQLANGVVDTNAMARDAVRAVAALQPRPDALLLTGDLVEAGGPESY
AHLLELLAPIELPLYPLAGNHDERESLARAFEGRIGPHTARLPGFWQYAAALGPLRLLAL
DTVVPMKGHGALCARRLDWLDQRLTEDATPTLIAMHHPPFATGIGHMDEMGLLEGAEALE
AIVRRHGQVQAILCGHLHRSIQVRFGGTVAMVCPSTAHQIALNLLGSSADGYVMETPGFQ
LHLWHGGRLVSHTAPIGDFGGTKPFA
>A0A3S5E5V5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Achromobacter spanius|TrEMBL
MPRVHPLARRHDAPAMLVQLTDSHLFGEPDTAMLGVNTDASLRAVLRQIEADGKRPDLLL
ATGDLSQDGEAAAYRRFAAILGQAGVLSGAQIRCLPGNHDQPAVMRQELPQWSAPVTDVG
AWRVVTLDTTVPGSNAGHLPDSQLDMLEAALAAEPGRHTLIAMHHNPMQIDSHWHDSMMI
DNPQALFKRLTRWPQARVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNLA
PGYRWIKLYQDGSMATGVRRVQDALWHTALAPDDAQAA
>A0A143QR92|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodococcus fascians|TrEMBL
MAGLSRRQFVTRVGTLAAAWGIAPQVLGHALVARAQPASGETDVGGTLAQTILRSSTGPG
RYRVLAAGPGEPYVPRLDILGRAPSASRVQARRSLLYLGHLSDMHVIDAQSPGRIEPMIV
SDHAAWGSAFHPQDPLTVHVTAAMVKAFADARISSVTGAPMGAAVVTGDSADMHSHLELR
WYIDVLDGVAVRPTSGASDVFEGVQAWPEAQWAYRPGDPSGGSFGDYGFPTHPDLLTQAM
SGTVESVGLPVPWYSVYGNHDTLLLGTFDLSSQLHALAVGGQKAYTLEATATSALAGYAS
TGSPLQRMVDALGVGSGARPGFRAVSADPARYLFEQREFMQEHFETTATPGPIGHGFTQH
NLDSGETWWAADPTPNVRTFGLDTCNAVAGPDGAVPEDQFDWLTQQLEKAQAERKLVLIY
THHNSLTLENRAQRPGQSVKLYGADEFIDLLLKYPVVIGWLNGHTHQNQILAHSRDGRGF
WEITTASCIDFPQQQQVVEIVDNRDGTLSLFTTVLDHASPITPGNSGSYLDLASRSRELA
ANDWAENPLMRRGSRLDRNTELLLPAPFDLSTITDAALEQQHLDEHARLIAYETRQGR
>A0A0S4V8P0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ralstonia solanacearum|TrEMBL
MSKNITVVQITDLHLLADPDGQLHGYRTYPVLSDTIDAILNYDVKPDMCFVTGDISQDES
EASYDLARSELERLGIPVFWIPGNHDDRDQAAAAFGKSERIRRLMKLPTADWDFIYLDTC
RRGADEGYLNDADFDRFVSEVRASVGQGKHVAVVMHHHPVPTQTPLMDTYILQEKERLLT
VLDDHPQVKLVICGHVHGDYQLQYGNQAIEMCPATCFQWEKGASIIKTEDWRGFRMFEFS
QSGYRSAFVSA
>A0A425I9B4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii CAST|TrEMBL
KGVLLDLSLGPACGGVSRERRASCSAAVSSTSSRESDRREAIARDPDLTETERRDAERRG
MERKATDDRQKKARFLVVPQLVEHELLCHVGILWSLDLFKLDKECNGNALLHVGYQLLAP
LLAAGYLTCSREVVLDFLYSLQCLYIDTPYHNQLHAASVAHLAFSICHFLDLFAPLENAP
GDAAASQPVFAQYLSLAIAALGHDAGHPGRSNAFLVQTSSTLSVVYNDRSILENYHACLT
FYTLSHRKSNIFRGKTVTQYRDVRKKAIELILSTDMSLHFEFLTRVAARRENPDFNFVDR
EEDRALVLSLAIKVADLGHCALDWEAHTLWSARLKEEFLAQGDEELRLGLPVSPLCDRTQ
QGQLARSQANFIEFLFLPLAQHLAAVAPDDRFEATVVTRARQNISMWEGAQDEVDQASAK
>A0A517SBE9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Caulifigura coniformis|TrEMBL
MTCHFSGIEHPIGRRAFLQRAGLVLLGSAATSGWSAESGTPLRIGLITDLHYADKEAAGT
RYYRETLGKLASAGAEFASEPPAFLVELGDLIDAADGVDVELGYLKRINREFASLCKDRW
YVLGNHCVDLLTKEEFLGGVEQEKSYTSFDRGGWHFVILDACFSSNGKPYGRKMSSWKDA
NIPPAEMEWLEADLKAAKRPTIVFAHQRLDVSNDHGVKNCPEVRKLLEQSGNVQAVFQGH
SHKNDYKEIAGIHYCTLRAMVEGSGPENSGASLLTLREDGAMMLKGFRQQSSYDWPRG
>A0A5C6DZ44|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Novipirellula artificiosorum|TrEMBL
MPIHFASQSRRTFLRSLSAAGTVAFLASHDRVSAASESTRSPAIDKNLIALLSDTHIPRN
PSVEAHGVNMTDNLNDVISQISSLSVRPANLLINGDCAYLKGLPTDYANLANCLAPLDDL
GISLHVTMGNHDDRTALYETFSEQRPAAAAVASKHVSVLECEFVNWFLLDTLTQVNVVTG
EVGNEQLQWLARELDARRDKPAIVMAHHTPQYTEPEPGKPWSGISDTAAFFDVLDNRSHV
RGFLYGHSHKWNVEERRHIKLVNLPPVAYLFSQGLPNGWVSARMSNDSLHLELQTLNPKH
PDSHQQVEISWS
>A0A812BYI7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sepia pharaonis|TrEMBL
MGYKATSLLCMPIRNAGDEIVGVAQIINKRGEGENNLFTKDDERPYLSIYLSIYLSIYLS
ITVVHLCLCLSLSISICSYLFIYLSLFISIYLSIYLSISFCSHQVISIYLSIYLSIYLSI
SAIHIYLLVYVWEGVSFFTFLLLLVAIVFYSFLSLSRHFSSFFFFPFLPFHIRHFRSPLF
FFHYSFFLSFSLFLCFFCFLVLYHLSFFFFIPFLSFSLFLFFLFLYFFSFFFFIPFLSFS
LFLFFSSCFLFLYSLSFFRYFFSSFIFFRFLYTFSFSVFDLFSSFLFFLSLFLPFFVVLN
FDYIFSFSFLFFSFFLSLSS
>A0A812DQ14|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sepia pharaonis|TrEMBL
MVRITLSTAQNTDIADIFQITASAAVVDIAAVPSPPTQTAAAAAAAVWVVPAYAVAVSSI
VATSASPQRLCLEHPAGEAKLPPWLTHRHYILRLLPLRWCRLRLRCRILARTQFRQLTVS
TTSSTVSSAVLHDYEHIPSAAETHVCTHTSTHCKYLRTQANRVLSIYLSIYLSIY
>A0A1L3L9W0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sinorhizobium americanum CCGM7|TrEMBL
MKLIHLTDLHLVPPEATLFGFDPAERLRKTVERINRDHADAELCVVTGDLTDEGDVASYG
LLREVLKDMRVSTRLLLGNHDSRENFILAFPDEQRDENGFVQSVYESSVGRFIFLDTLVQ
GHGHGALDGGRLEWLLARLAEKPEAPAYVFAHHPLQPIGLPHFEPWNTANWRHIMRSIVA
AGNVRHIFHGHVHVDVGGTWHGVPFSASRGVAHQIIPHFMRRDADFVEDAPAFDVALIEN
DGFLLHRLEVSDRPVVAVSAAG
>A0A3E2MWN3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mycobacterium marinum|TrEMBL
MHRLRAAEHPRPDYVLLHISDTHLVGGDDPLYGAVDADSRLAELLEQLKHSGASPDAVIF
TGDLADTGEAAAYRKLRAVVEPFAAELDAELIWVMGNHDDRAALRRFLLDEAPSMAPLDR
VTMIDGLRIITLDTSVPGHHYGEVRDSQLRWLAEELKTPAPHGTILALHHPPIPSVLDLA
VTVELRDQARLGRVLEGSDVRAILAGHLHYSTNATFVGIPVSVASATCYTQDLTVEVGGT
RGRDAAQACNLVHVYPDTVVHSVIPIGSGKTVGTFVSPAQAKRQIAESGMFIEPSRRDSL
FSHPPMVLTPSVRPSPAD
>A0A2X4VEU8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serratia plymuthica|TrEMBL
MESLFKLTVASGARVRILQITDTHLFAGENETLLGINTYRSYHAVLDAIMAQQRDFDLVV
ATGDLAQDHSLAAYRHFAEGIARLPAPCVWLPGNHDFQPAMVDALAAAGIAPSKHVLLGE
NWQVLLLDSQVFGVPHGELSDYQLEWMERCLQAHPSVIRYCCCTITRCLPVAPGSISTAC
ATRTCWARCCCATRT
>A0A0B1TS16|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oesophagostomum dentatum|TrEMBL
MLFVYRRICDEDDDLAEVTPETVPDEVREWLAATFTRQNAGKKREKPKFKSVANAIRTGI
FFDKLFRKQQSVQCPIPGEMAELLREINSWSFNPFQLNEVSEGHALKYVGYELFNRYGFM
DRFKIPLAALENYLHALELGYSKHNNPYHNVVHAADVTQSSHFMLTQTGLANSLGDLELL
AVIFGALIHDYEHTGHTNNFHIQSG
>A0A6J4SHS7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Solirubrobacteraceae bacterium|TrEMBL
MSRPTPDGTQRVDANRRSVRRRRLGALLALPAVLAAGVGLVLGARGDAAAPAVTTDSTLR
ATWIDRDGDGALERGPGEPLRDRTDLAPAARPGRVLATLGQITDTHVRDEESPARVSFLD
RLGGPFTPTFRPQETLTTQAFAAGLRTLDRERPDLLLVTGDITDNGTRAEYDQALAVLRP
GARVDPDTGAPGYEGPQEATNPDPAYYRPDVDPPVERGLLARAQAPFTAPRRRAPWLPIP
GNHDLLAAGEVAPSAAINAIAVGSQALIRPREGLDVPRDPRGASAVVEALVAGGELPGET
AQVTPDPRRRFLTPAEGRARLRAASALARTPADPAAPGLSAVRDVGDRVRVVTLDFDQAG
EGAGGVASAAHVAFLQRALRTAGTRWVLVASHQPLTKARGGERLLRVLDRAPRVLAALAG
DTHHHRVRARRSAAGGYFLVETGALADFPQQARTVRVREAQGGGAVLETWVVDTSGAGRV
GALADVAREIAFLDAQGGRPGGNRERRSDRNVRLFKAAPR
>A0A0P9FHQ4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudoalteromonas sp. P1-9|TrEMBL
MTWFSQREHFDKAQLTLVHITDSHVFAEPNGEYFCVNTANNLAKTLACIKSIDCDAIIFG
GDLTQDHSEASYHLFAQLVQQAGLSGKLFWLPGNHDEIGVYREVFSQYGIRDSKVLENEH
WQVLLANSKGPTPAGFVSETHLNEIQNELTNNTKHALLFTHHHPIPIQGYLDKHMLENGE
ALLSQLTQFKKVRGLIHGHVHNEYSWLFNEFAVFATPATSIQFEKNTSDWQQVDLGPAFR
MIRLQQNGSLNTQVVWLNNA
>A0A378ZU95|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pannonibacter phragmitetus|TrEMBL
MYILHFSDFHLFAADKESAHPRPDTVAAVERVLADAASLTPQPDLVLISGDLADCGSAED
YALARQMLARFDAPVLVVPGNHDRREAMRAAFAGTIPFTPEPFLNFDMVHKGIRVIGLDT
IIPGKVEGELCAGRLGWLAERLADEKAREETTSGVTFFMLHHPPFGLASPAWDWMTLTAG
RDELRTLLAGFPGHLRLLTGHVHRPLITSFAGHFAAIAGSPAFQYAPGLGWTSEPPLSAE
PYVYWLHHITGFGGVITSPRMIDLG
>B8BQP3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thalassiosira pseudonana|TrEMBL
MGGYNFIDHLHLQPSKLINSLRCIESWYNDVPYHNNIHVLDVLHTVNVMLPHDNTIHFSF
LDNITSLDVYSILLSAIIHDISHEGLNNLYYQNNPLAFHDELTLEPFHDVFGRRLLQRHG
AFEGLSDEEQKYSEEVISSAVIGTTMANHFDLFTLLQNEVQSAFSDEDGAATSEDGMDTR
YNKTAFLSFLVHAADISSPTKPFPMFSQWIPRVFTEFFRQGDLEGKQGHPISPLCNRREL
TEQTIAESQVMFINTFVKPMYELIGKICTWIKEDVVPLLDANLNAMTSWVDELKVKEKRE
ATK
>A0A6J4IAZ0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Acetobacteraceae bacterium|TrEMBL
MAPFCFLHFTDPHLPPPGGAVLGDDPAPALAAALADAVERHGPDGPLPASFAVVTGDLVR
DGEPAAYTRLREVLGGLPWPVHLLLGNHDDRRAFRDAFPEAPVDEAGFVQQAVPTPAGTC
LMLDTHAPGRPDGELCARRIAWLAARLGETTGPVLLFLHHPPLPVGIPFMDGMGLKDADA
LWGALAPHRGRVRHIFHGHLHRPIAGSWRGIPLSSLRGTAFAVSLDQQPGKAAVSHLEAP
CYALARALGDDLVVHTVELPDARRSA
>A0A157SCL1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bordetella trematum|TrEMBL
MLIAQISDLHIRMPGQKAYRRVATDRYLPPAVAALNAQQPAPDLVMITGDLTDFGRPAEY
RYLRDMLDPLRAPYYLLPGNHDEREALRNAFPDHGYLQQPGPFLQYTIEDQPLRIIVLDT
VVPMQSHGMLCEQRLAWLDARLREAPERPTVIAMHHPPFKTGIAHMDAIGLLEGADALES
LVKHYSHIERIMAGHLHRTIFRRFGNTVVSTCPAPAHQVVLDLRPQGPSAFNLEPPGYHL
HHWNEGHLVTHHAHIGEYPGPYPFHENGELIDD
>A0A1S8NJ93|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium saccharobutylicum|TrEMBL
MKSKILSLCVSLAIAETLIASPSYLTKANAAVSYNSTSINANLNATTVPDHIALSWTGDP
TTTQTITWRTISTTNKCIVKYRVKGTSTWTTTNDVNPKTLTTTTGDATVTTGTENIYSTT
LTNLTPGTTYEYQVVGTYINDEAGIYTTNTFKTESNNNTSTKFIVFGDSQSGIPTNPEYT
PWHNTVTEAYDQNPDANFVVNMGDLVEIGQSYQHWNNWFAAANGVINNIPEMPVQGNHET
YKNNDYDSSSPQDFTSQFSVPQNGPDGHIGQTYSYNYGNIHFVVLDSQEDEEAPENDSFL
KQQASWLDNDLANNAQKWTIVMFHKTPYYNKQTRNNPAVKDILTPIIEKHHVDIVFNGHD
HGVSRTYPINRNNYYSDYSKGTVYYVTGRSGNKYYTDLNNKIWDANFIDCQDSPSYEVVK
VVNGKLTIDAYKYNTIDTSSTNPKNALYNTPTKIDSLTIDKDNPSDSTPLTLNQSQSTQL
AIAGTVQSGYDVTVSNGKGYIDPSLIAKYYKGTYDTDSLTLTINKKSYTFDKTDLLNGDS
SKVNIDALYKQGIDVNYNSQLNCVLIDFTGRITSDMIASFKGFEL
>A0A0L6CSN0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseovarius tolerans|TrEMBL
MQKVIVFTDIHLVSEGKTIIGIDPFARFMQGLAHALDNHPDAARVVLCGDLTHNAAPPEY
ARLRAALDTCPLPVSLMLGNHDRRAPFLAAFPEAERMETGHIQHHADIGNYRLICLDTLN
EEAEDTHSGWLCAARLDWLKERLTEAGDRRVIVFTHHPPIETGFKGMDWIGLKNRAELTA
RLAAGNVVQIVSGHIHRTIQGSAGGIPVAILKSTCHQMPMALGFQDPSLSIDEPGAYGLL
LLTEAGVVVHSEDFTLPPGEAQIYT
>A0A3G6ZT14|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. CMR5c|TrEMBL
MPSVSASPTDDSVLLVQLSDSHLFAETHGTLLGMNTADSLQRVIDLVLAQQPKIDLVLAT
GDLSQDGSLQSYQRFHQLSAQIPAPARWLPGNHDEPGIMQLAAQGSELLQPVVDIGNWRI
TLLDSSVPGSVPGFLQDEQLQLLARSLDEAPGRHHLICLHHHPVSIDCAWMESIGLRNAE
ALFEVIEGRPQVRALLWGHVHQEIDRRRGGLRLLASPSTCIQFEPRSDDFKVEERAPGYR
WLRLLADGRLETGVQRVEGYAFTVDYGSDGY
>A0A1S8L9R9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium felsineum DSM 794|TrEMBL
MNKKRGLLSFLITTITALSVFSVAAVKANAQYEFDVISDTHIGSDDMGGWHATRNLKTTL
NCIAKYHSNDQCVVFNGDNVDTAYQDSYDQLYNTIAQVKNDLSSQGKTIPYMYFNIGNHE
YCFGGTNTGNYQTCLNNFNYNTNRIRSMIGSRAGVTDTNRANSYDLQYINNKNDRLAFLG
TDELPSNPCDAYLAPSQIDWLNSTIIKNKNEWTTSSRGKKPMFVFLHQPLQNTVYGSDPT
NPNFADWGTLLNTDTLKQYALRTNHPEVIMFTGHTHRDFDGSYYGDSENFCTLTPSYSSV
FGVPSIGNTDGDPEGYHVTVYSDGVVVQGVKYTSSGTVQVNTRTINF
>A0A1S8LEW7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium felsineum DSM 794|TrEMBL
MGLYAISDLHLAFNLNKPMNIFGEDWSNHDEKIKKNWIDKIKEEDTVLIAGDISWSMDME
NGEEDLNWIDSLPGKKIICKGNHDYWWKSITKLNNMYSTISFLQNNFFQYEDYAICGTRG
WIDKSFDNFDEHDKKIYKREIIRLRLSIDAAVKKGYSKIIVMFHYPPFKDESSLSEFTEV
LEEYNVEKVVYGHIHGPALKNVQGRISKNNIEYILTSCDYIKFNPIKII
>A0A1V5GA10|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bacteroidetes bacterium ADurb.BinA245|TrEMBL
MEPEKGMAKALHHAQNLHPGVSFIINGGDAIMDALAADKQKTATQFDLFKTILKNENSLP
VHHTIGNHDIWGWFIKENRPEDDPQYGKAWVVDTFEMKNRYYSFTQQKWHFIVLDSTQLN
AAGGYIARLDEPQLEWFTKELESVPKDHFICLVSHIPILSICAGLYFEKTEANGDLMIKR
NLMHTDFLSLRKIFANTPQLKCCISGHIHMQDELTYQGIKYYCNGAVCGNWWKGAFNNFE
PAYALMEFYDDGHTKRTIINY
>A0A376FFF6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Enterobacter asburiae|TrEMBL
MGAPVRILQITDTHLFAEKHETLLGVNTWESYQAVLSAIHAENRACDLIVATGDLAQDQS
SAAYQHFAEGIASFSVPCVWLPGNHDFQPAMFSSLQDAGISPAKCVFAGEQWQILLLDSQ
VFGVPHGELSEFQLDWLETKLAAEPERHTLLLLHHHPLPAGCSWLDQHSLRNSAALDRVL
AKFPRVKKSAVWAYSSGTGSRLERTPHAGDTVDLRSV
>B5FDY9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Aliivibrio fischeri (strain MJ11)|TrEMBL
MFKNKLAVLFTCLSVFSFSAQSGSFDTVTLGSKGGIQDGNLTAFLIKSEADSNFVMLDAG
SVVNGLIVSEQKGAFKDIIVPDSSPYTKVGYLLKDRIKGYFISHAHLDHVAGLIISSPDD
SKKPIYGLAATNKDLMKNYFNWSAWPNFGNKGEGFKLSKYNYVDLQPGAWSSIAETTMSV
MLLPLSHSGGQSTVFILKDSEGDVFAYFGDTGPDEVEKSSAMKTAWSALASFVKQGKLKG
IIIEVSFTNETPDKSLFGHLTPNWLVKELRVLEGMNGKGSLNDLNVAISHIKYSLKNSED
PKIIIQKQLAEANNLGVNFIFPEQGDSLQF
>A0A1C6YZX2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Hafnia alvei|TrEMBL
MRKTLIAVVLAGYSAFTWASFDVVALGTQGGLSGDNLTSYLIRTEGDARYIALDAGSTLP
GIAKGIEKGSFPDVTPEKAAPLTPQGYIFREQINAYFISHPHLDHVAGLILGSPDDKKKT
IYTLADSANTLHNHYFNWKSWPNFSDSGNGERLGTYRINSPRVGQTFTLGVTPMRGVIYP
LSHNGTASSMLLISARGESFAYFGDTGADAVERSKNLDAIWRVLGPLIQQKALKGMIIET
SYDDAQPDNKLLGHLTPKLLLSELAQLEKYSGGAGSLKDLPIVISHIKPTLVAGKDPQAL
IQQQLSAGNSLGVKFMFMQQGDKAVF
>A0A177HPN4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces jeddahensis|TrEMBL
MIRVAAVGDIHMGRDSRGLFRPAFDTLHDCADLLLLAGDLTHHGKPDEAQIVADEVAGLP
VPVVAVLGNHDHHDERPEEVTDILRSAGVTVLEGEGAVFQVGDALVGVAGTKGFGGGFAG
RCGSEFGEPEMKSFVRRTRSCADGLRTALEQLEQAGCAFRIALTHFSPVPDTLAGEPLEI
YPFLGSYLLAEAMDEAGADLAVHGHAHQGTEHGITSGGIRVRNVAQPVIRRAFAVYHLHE
HPQEKGAKVA
>A0A1Q9R0Y0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas putida|TrEMBL
MPHANPASSAPVRLVQLSDSHLFADGEGSLLGMNTRDSLQRVIDLVLAEQPHIDLILATG
DLSQDGTEASYRHFRDMTAVLGAPTRWLAGNHDEPLPMERVAAGTDLLQQVTDIGNWRVI
MLDSSIPGSVPGRLEANQLHVLDQALSSAGGRHCLVCFHHQPISIDCAWMAPIGLRNPEA
LFETIKPYPQARALLWGHIHQEWDQHLDGRRLLASPSTCIQFEPRSTDFKVDEQRPPGYR
WLALHDDGRLETGVSRLSDFAFSVDYGNGY
>A0A1E7X9I6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lentilactobacillus sunkii|TrEMBL
MAAYKIVQITDTHLTADGDKPANHQRVDPAKKLADVFDDIHDTEVNPDLIVISGDLVHNG
HPKDYRHFQKYLAKEEKRQNARIQVILGNHDRTKAFYKGFLKDDPKARYFYKVPTDIWDL
YFLDTKCGDIEQGYIDADQLEWLQTSLSESSKPAVIFMHHPLAGPTLEHMHYSILQNGDE
LLKAIPEGKVKAIFAGHIHFAASYQVDGILNVVSDSTAYHIDCSNHHHHFANDATAYSVI
NLDEKGIGVEQRRLRFGRKTIKTFDIPDTGFVDHKIIQDELDRVRESLEEK
>F5S244|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Enterobacter hormaechei ATCC 49162|TrEMBL
MLTMSSPDYVTQNEYPLDDDTTLMSTTDLHSYMTHTNDTFVQVSGFSLQELLGQPHNIVR
HPDMPKAAFADMWYTLQKGEPWSGIVKNRRKNGDHYWVRANAVPMVRNGQMTGYMSIRTR
ATRDEIAAVEPLYQALNEGRCKKRIHKGLVVRKGWLGKLPAMPLRWRVRSVMAGLFAVMA
ATLVASAAGWASLVAAAVVMLLGTLVFEQQIVRPVENVARQALRVATGERNSVQHLNRSD
ELGLTLRAVGQLGLMCRWLINDVSSQVVSVRDGSDRLAQGNEDLNDRTRQTVANVQQTVA
TMNQMAASVQSNSETAAEVDKLSMAASSAATQGGTVMQTVVKTMDDIADSTQRIGSITSL
INDIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRSANAANDIRKLIDASASK
VQSGADQVHAAGRTMDDIVEQVKNVTQLIAQISHSTSEQATGLTELTRAVAELDSITQKN
ADLVEESSQISAMVKHRAGRLEDAVTVLH
>A0A139XZD9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii ARI|TrEMBL
MRLREHSLLLCVDAMSRDSPVASPAHSGVFGPSADAEVSEVFSLPSLSAIPGAASASSLS
RENSLISSQRASPSVSPPAGSPLWRLVRRCGQGEGERENVERCRLRERREECGAARRGPP
ASAATSDCSCPSAGDRRRVQSRRRRARTFQGRSFCGNHVSTEAEREGETEGEEETEGEEG
REEYDSKRRGRLARRLGRRFVIAAVERGRKREGEETIVLRGNQGECWQEAQRTADSPDCS
SSSVCCFGGSCSTASQCCACMRLASVSCLSPRSSFSTFHCSLPAVSSASAAFVCPREPPG
SDSNSSPSCASSRGFSPSSPKATVSSSRPSSSSASPLRSSLSAPSGLFPVGSGCSSDVCV
SVPLPALFRGCRVHSSAPSSRTEQGTALLTGAPPSANELEAASAMANPTNSSRFSRVKTV
SFATLSECGSSHISRRSDSASEPEAEREKPGLCSMRVARRESSPAARSPGRQSERRGTDS
SCTSLPQRSDRAGRDRVGSRGSAEQRSSTSSRRVSDHSRAEAGLWSAGPGDSGASLEPDL
ESRSAFLRRCRARVAAARRKVCQAFQSLAEHDLVFRMKEDLAQMRHESSLRSVFADACRE
RSGVEMSERTRLSVGGGTGRHLSVGTSTHKEGSTHKEGSEKERIRDGGSASPSTHLSRSG
SGDVILRRFPLKFVDRGLEDLFADNINRWMATRLLLMGVLSLVVTSVMWPLMAWSFNLLD
AFNHSEPLGILFHINMAVTVFVAVLFIVTKRCRHLAEHAELIADGGTFLVVTIWGIWNTT
ASYILEHSYVQDVIGSAYPMHPADAPISLEKTSAWSTSLEASSAVAYLYGLLLIVQLDVV
YPSRTRRTWQVHLMFFGFSTASIVIRGALNPDFVPVPFVVIRALTYLMLTVFLFIGRHAT
ELQQRHTFYNWL
>V5BGF7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Methyloglobulus morosus KoM1|TrEMBL
MTDPIPYVSILQLTDSHILGTPEATLLGIDTAYYFNSVLEHAFNSAMRFDLCLLTGDLAQ
DPCPASYRHLLDKLEDYDIPSVCLPGNHDDFGMMQEILNTERINCRKQVFWGNWQIIALN
SQILDSPNGYLAQAELSFLEQCLKQHPDLFTLIAIHHHCVPSRTVWMDSMMIGNAQDLFD
LIKPFPNVKAIVNGHIHQEMDIQFDSVRVLTTPSTCFQFKPHSKQFSLDDKSPGYRWINL
YDDGRIHTNVVHIPEPLVGLQTDTHGY
>A0A1V5MHV7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|candidate division TA06 bacterium ADurb.Bin417|TrEMBL
MFNLFKRAKFYTGLGLLLLLTLALSFATQARAGAYKEDFESLTAGASLSGQAGWTAESFV
TVEEGSGHTGKKALRVAPTPAAGRAFQRTLEWDAGWKEVWVDAYLRIPRSPQLALLEVQK
GGQMVAAGGPGGPGEAGSGFVFRSSRGQNIGWPRMYERASNPYTGESSQLKPETWVRLTM
RLDLEKKEFEVYRDGKCVFSEMEMAKALPAAGEYILRLTTSPIKAEANPADFTFYIDDLY
LGPDKPAGIEPAQVVPPRPKNTLVRVVVVGDTQISASEAKSKGSPFGTLGPIIATANRLE
PDLVLFVGDQVNIGGDPATFKDQAAVLYPVWTEEMKRLKAPYYTTPGNHDPHALYKQYLR
PELDYSFEKNGVTFISFSSSAPENPDDWSHNGKVSPEQLAWLEKEMAKAAAKKNRIVTFT
HITSHPNKHPLVGWYIQEGGAELRALYDKYGVFAELSGHMHRWLASWKENKTWYLVAPGT
MGGGYVAGAGLAVYDILPDKAFQYEKPTKMPYFNSWGQWAKPELD
>A0A378MV45|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mannheimia haemolytica|TrEMBL
MHEYIKLPVTGVIKLLQITDPHLFSNPEETLLNVKTVKSFSAVIEQINKQAKQYFDLVLA
TGDLIQDNNIAGYHYFAQITNSLNSPIVWLEGNHDVQPSMSEILAQYKHILPINKFYSVS
NGSF
>A0A485AYC0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Raoultella terrigena|TrEMBL
MLLAQISDTHFRSHGQKLYGFIDVNAANADVVSQLNALQERPDAVVISGDIVNCGRPEEY
EAARQILSGLNYPLYLIPGNHDDKALFLEYLHPLCPQLGSDPQNMRYAVDDFATRLLFID
SSRDGTSSGWLTDETIKWLEAQLFDGGDKPATVFMHHPPLPLGNAQMDPIACENGYRLLA
LVERFPSLTRIFCGHNHSLTMTQHRQAIISTVPGTVHQVPYFHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTQER
>A0A665UBB3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Echeneis naucrates|TrEMBL
MVRRPARRSDEKPKFRSIVHAVQAGIFVERYNYIFTHHKCTLFSLSLQDVDRWSFDVFAL
NSACSDHALQTLFFELITRYELNSRFKIPISCLTEFLSALERGYCKYNNPYHSHVHAADV
TQTLHCLLLRSGLVHWLTELEVMASLFAAAIHDYEHTGTTNNFHIHTKSEFALIYNDRSV
QESHHLSAAFRLLQDDQKNIFINLSREEWMELRSLVIEMVLSTDMSSHLLQVKAMKSCLQ
QQERIDKPKALSLLLHTADISHPSKPWALHSRWTKALMEEFFRQGDREAELDLPFSPLCD
RKTTPVAESQIGFIDFIVHPTFSLLTDMAEKIVIPLVEENPGPPDPCNRHSNLWKESSRG
LQWSLAHITAELVSFRSTWTRHTEDNKVKWKENGSNGMLQCVHSFS
>A0A212KMC9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Alphaproteobacteria bacterium|TrEMBL
MLIAHVADLHVSADGRPVHDLVDTDAATRGVVDAVNAARPDVVLVTGDLTHDGDAAAAGR
ARDLLRRLDAPVYVCPGNHDRRETLRAAFGRRDDDRDDAWMAYVVEDLPVRLIALDAATE
DPMVGALETAQVDWLAARLAEQPERPTAIFLHHPPFDTGIDWLDQIGISEGRDDLGAVLA
AHRNVRALLCGHLHRPMRGAWYGAPVIAAPSVMNRVAFVGENADGSPVTEIAAPPGFVLH
RVVNGAWDPNMCFLNGHSEPWLAAMPDPWANNP
>A0A2G9U3A3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Teladorsagia circumcincta|TrEMBL
MDKGGATEIQPFGVFVRRRILAAHRDLTRIPNAIEAFASYWKPDSSPTTDDVHSQHPQST
PGTSSGNQSPTIKKPVISKERGSLCDTIVTTVDGQKFDTKDLDNDRGMAMVADWSLPIFE
IAEKHNKTVLSRLTYTVFKQADLFRIFKLSPIKFFNFFHALERGYWDIPYHNRVHAADVL
HGCYYLTCHPVRPLIGPTTSPDSLLPPPLTLAAPISASMSTLELMALYTAAAMHDYDHPG
RTNAFLVAAEDKKAILYNDRSVLENHHAAESWRLLQLAENNFIETLDPAETKRFRYLVLE
YILATDLKQHFEIIMTFNEKSSEMELQNESDRLLMAKMVIKMADINSPTKPYALHRQWTD
RICQEFYEQTERRVVEQLFYEVHEVSRKWHFNTNDFLHEKKEEVNTGSQL
>A0A1N5XP67|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mycobacteroides abscessus subsp. bolletii|TrEMBL
MTGEQDPSSMSRRQLIRHTAWFGAAVALTVAGGEVISHVAGSAAAAATTRPTLRFAQISD
SHLGFNGTANANVVDSFGHAINQINNLGYTPDFVIHTGDLTHLATDAQFDQAKQMMSGLS
TPHVFTVPGEHDSIDDAGQKYRSVFGDGTRGDGWYSFDIAGVHVIALVNTLNLKKLGHLG
NDQLEFIEKDLAPVSSDTPIIVFSHIPLFAMYPEWGWGTDDSAQALSYLKRFASVTCLNG
HVHQLFTKTEGNITFYSGTTTAYPLPKPGDGPAPKPVTLPAGQLHDILGIREVSYLRGTQ
PLALKEDKLR
>A0A1Y6IV88|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio mangrovi|TrEMBL
MDKIVQISDIHFCIRDKSHDSRKNLSLVLNKINKLYDEYILVLSGDMVMKADKAHYIELY
KYIRNFTQNEIYVIPGNHDDIALMRELAKQADFFKIQDTLEIGNNDIVFLDSSEKGEYLG
GGKIDLSHFEVIKSKLRENSNKIVFIHHPPFKIGAEWFKKICLDNGDLFMKSLLKINNLK
YLSYGHCHNYFIEERENTVFLSCPSSWIQFDHSCHHEMKYDQKREIGFNVFHLSDDIYHD
TVTVSDH
>A0A6J4XV68|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Olavius algarvensis Delta 1 endosymbiont|TrEMBL
MLICQISDFHLKPKGALAYEAADTAGALEKVVDHINRMAPLPDVVIVTGDLADGGSLESY
RLVNDLLSRLKSPFYTVPGNHDQKDNLAQAFPEHKYLAQRVSGKNGSYICYVLEDYPIRL
IGLDTVTPGEHGGGMGPGRLDWLRRKLEERPQAPTLIFMHHPPFASAIGHMDTEPFSYRS
QFRELIENHPQVERITCGHIHRPISCRFANTVANVCPGVGMQIVLDFKADAPSGFVMEPP
AMLIHRWGNFWDDQPALLTHTSVVEDFPGQYGGFHPFFDVVNPS
>A0A259UL50|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sporomusa silvacetica DSM 10669|TrEMBL
MKIFAIADTHLSGQPVVKPMSIFGSHWEGHWEKIKASWQKQVTDEDVVLLSGDISWAMKL
TDALVDLNAIANLPGRKIMIRGNHDYWWQTVSKMTKATEGKFEFLNNNFAIAGEWAICGS
RGWTCPEDPLFKSKDQAIFDRELLRVEASLSAAHAAGFSRIILMLHFPPFYNHQTETGFA
GLINNYPVIHCVYGHLHSESSIKAAATGMINGTTYHLVSCDALDFTVKPLI
>A0A142YA18|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Planctomyces sp. SH-PL62|TrEMBL
MNANSPDVVRIGRRAFLTGGALVLGAAPATIASTLRAGERPAVRFGLITDLHHADKPPAG
TRHYRESLPKLAEAAERFRREEADFLVELGDLIDAADSVAVELEYLDRIDREIAAIAERR
HYVLGNHCVDTLTKPEFLGKVGQERSFYSFDAGDHHFIVLDACFRSDGEPYGRKNSEWTD
ANIPAHEVEWLRADLAANPKPTIVFAHQRLDVGSPYGVKNAAEVRAALEASGAVRAVFQG
HSHKNDYREIRGVHYVTLVAMIEGSGAENNGYSLVDLDAGAIRVRGFRRQRAYDWNAPTG
R
>A0A0S4HTG8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. URMO17WK12:I11|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEADGTLLGMNTRDSLQKVIELVQLQQPNIDLIIAS
GDLSQDGTLESYQQFRDLTGQLDTPARWIPGNHDEPQIMAEAAVKSALLEPVVDVGNWRV
TLLDSAVPGSVPGYLQDEQLQLLVRSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDQLRNGVRLIASPSTCIQFEPGSDDFKVGEQAPGYR
WLRLLPDGQIETGVERVTGFDFEVDYGSNGY
>A0A086Q331|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii VAND|TrEMBL
MRLREHSLLLCVDAMSRDSPVASPAHSGVFGPSADAEVSEVFSLPSLSAVPGAASASSLS
RENSLVSSRRASPSVSPPAGSPLWRLVRRCGQGEGERENVERCRLRERREECGAARRGPP
ASAATSDCSCPSAGDRRRVQSRRRRARTFQGRSFCGNHVSTEAEREGETEGEEETEGEEG
REEYDSKRRGRLARRLGRRFVIAAAERGRKREGEETIVLRGNQGECWQEAQRTADSPDCS
SSSVCCFGGSCSTSSQCCACMRLASVSCPSPRSSFSTFHCSLPAVSSASAAFVCPREPPG
SDSNSSPSCASSRGFSPSSPKATVSSSRPSSSSASPLRSSLSAPSGLFPVGSGCSSDVCV
SVPLPAMFRGCRVHSSAPSSRTEQGTALLTGAPPSANELEAASAMANPTNSSRFSRVKTV
SFATLSECGSSHISRRSDSASEPEAEREKPGLCSMRVARRESSPAARSPGRQSERRGTDS
SCTSLPQRSDRAGRDRVGSRGSAEQRSSTSSRRVSDHSRAEAGLWSAGPGDSGASLEPDL
ESRSAFLRRCRARLAAARRKVCQAFQSLAEHDLVFRMKEDLAQMRHESSLRSVFADGCRE
RSGVEMSERTRLSVGGGTGRHLSVGTSTHKEGSTHKEGSEKERIRDGGSASPSTHLSRSG
SGDVILRRFPLKFVDRGLEDLFADNINRWMATRLLLMGVLSLVVTSVMWPLMAWSFNLLD
AFNHSEPLGILFHINMAVTVFVAVLFIVTKRCRHLAEHAELIADGGTFLVVTIWGIWNTT
ASYILEHSYVQDVIGSAYPMHPADAPISLEKTSAWSTSLEASSAVAYLYGLLLIVQLDVV
YPS
>A0A7Z0VNQ6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Thiodiazotropha endolucinida|TrEMBL
MGSSPDNQPPNFKQFPAESLNLLQLTDSHLYADPSRSLLGINTLETFDQVLAQALQETGN
PDFILATGDLVHDASDTGYKRLLGRLQLTEIPTYCLPGNHDIPGKMKQILNQDNVHCIPS
VQTKGWSLIFLDSTIAKSDGGRIDESQLELLRVLLRAHPDKHTMICMHHHPVPVGSRWMD
TMVLENPDAFFKLIDANPQVQAVLCGHIHQAFDTEYRGVRLMGSPSTCVQFIPRVDDFAI
DAIPPGYRWLSLQPDGTIRTGLNSLPKIPSGLDLASMGY
>A2QAW4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Aspergillus niger (strain CBS 513.88 / FGSC A1513)|TrEMBL
MQASELPFVGANPPEAASRGEGPGSPSLQIIVLGPTGGPREDRVTGLLVRSTSTKWSANS
IVAVDAGTLLCGIIDTLEPCDNNKKLSDQGPFAGLELPHNNVPANAAHVFRHIIGAVCIT
HPHLDHLSAFAINTPVLEAGSGAKTLAALPSVVAAIKTHVFNDVIWPNLSDEDGGAGLVT
YQRLMEGGNPMMGRGDEKGYTRVCEGLLAKCLAISHGCCRQRSSVDNDVQRRMSSAPFGV
DPMRLNPRAFSISFDEPETGYFSGARSPGYRVPGKDSWATVESSAFFIREPTTKREVIIF
GDVEPDSISLNPRNRRVWEAAAPKIVASQLRAVFIECSYNDDVDDASLYGHLCPRHLIDE
LIVLAQKVTELKYPDSFSVRKRKRASAPEAAGDPALSPKSKKAALAGEKGGGSRRGSART
SRRHTRARVAVEDIDENMEGSPAVSHAPSEVGMDVSLAESSDPLTVLQWPEPPLAGLLIY
IIHIKDDMNDGPPPQERILQELTAQGQAAGLGCEFRVPTRGESVLI
>A0A1I7V4J9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Caenorhabditis tropicalis|TrEMBL
VQGPSSSGPMTLSILKKAQTAAMNKISGVRKLRAPSHDGHVPEYGVNCAREIAVHMNRLD
DWGPDVFKIDDLSKNHSLTVITFTLFRQRNLFKIFEIHQSTLVTYLLNLEHHYRNNHYHN
FIHAADVAQSMHVLLMSPVLTEVFSDLEVLAAIFAGAVHDVDHPGFTNQYLINSNSELAI
MYNDESVLEQHHLAVAFKLLQDSNCDFLANLSKKQRLQFRKIVIDMVLATDMSK
>A0A1V4IJC6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium oryzae|TrEMBL
MAVYSISDLHLSFSSEKPMDVFGDSWNMHYERIKNNWKTMINEDDMILICGDISWAIDMD
QAMVDLKWIDELPGKKIISKGNHDYWWGSISKLNNLFENTRFLQNNYYVYNDYAICGTRG
WICPGLESFTESDEKIYKRELIRLTLSVEAAIKAGYTKIVVMLHYPPVNDKFEPSGFTEI
FKKYNIEKVLYGHLHGPFNSSLFHGISDGVEYVLTSCDYLNFKPVRIL
>A0A198UJF8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moraxella catarrhalis|TrEMBL
MPNITNNRTFNIVQLSDLHLTGDIGQAPSYQRFLAVFQTAKRLNPDLWLLTGDLVNDGNS
DAYDWLFNQLKVTKTPYLAVAGNHDVTHEIGIHLAHQERIHVPILPDQRLKNCFRYTFQA
GHDWQILLLNSSVSGEIFGLLTHETLLWLDQTLTTHFEQTIIALHHHPTKVGSDWIDAHL
LKNHQDFWHVIKKHAHVHTILCGHVHQVHTLHPLPAHQVQLLSCPSTDRQFMPFVDNFQI
ADTPAGCRMIQIDNTDTVSSYIQMVQNTR
>A0A2N7R4L5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. AD21|TrEMBL
MKNKEVKKLFACLCLLSLSSFAAANEGVPQHMVFASDPQYPWTEKSDSGEDESSASFEKR
SKWLVESQFESIAQFRSEMGGQAAVPLMINGDMTAFGHGWQRSYIRSMLNKYFGDNVLYG
LGNHDYQNNVNDCFSESCAAGSIVDYRDHHVDKVDEFDLEVTGSLFNKHYLGSLAYSKNI
GEVHLVQLNNEPTYQVKISHALNPTTFDIRQSLDWLENDLRTARAQGYAIIINMHKPYDW
AGSWDQEKRFREMIEKYQVTAMFAGHFHTDGGSKTYMGSVPMFLSGAASQETYLTASFSK
DRKQLEVSLVEGNQWRKRTPVATVPVKSIFASRP
>A0A1I8IFP0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Macrostomum lignano|TrEMBL
VFLDRSRGRSSGELDEDLFSQASVGATAATAAAGKVNGADLTDGVNGTGSAIASEVPDDR
VQEWLTNTFTRRGSVVATAGRRRRLRSLAAVVRTSVYFERLFRGGRSGAAGGDATAPQPP
PVPIGAPALAYLEAGAHRWDFDPFGLADLTGDRPVRNMGLYLFHKFDLIDKFGMQMETLE
AFLDMVEAGYKRHGNPYHNCTHSADVAQSCCYIVAHHGLADWLSDVELLALLFAALVHDY
EHTGTTNNYHVQTRSHLALVYNDRSVLESHHVSAVFRRMQEAKCNPLKGLAQPEYRQFRS
LVIDMVLATDMSTHFAQVSAMKDAIPCPENLPRVDILAYVLHVADISHPAKSWSLHQRWT
SQLNEEFFAQGDREKQLGLPCSPLCDREKTMVASSQV
>A0A484UER3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|plant metagenome|TrEMBL
MLIAQISDLHIRLPGQKAYRVVETDAYLPPVVDALNRLDPRPDCVVITGDLTDFGRPAEY
AHLRHLLAPLQLPFFLLPGNHDDRQALADAFPEHAYLRTDGPFVQYAVEQYPVRILALDT
VVPFKGHGALCAERLHWLETELAREPGRPTLIAMHHPPFKTGIAHMDAIGLLSGAPELEA
LVGRHPNIERIICGHLHRTIYARFGGTVASCCPGTAHQIALDLRPAGPSAFVMEPPGYQL
HTWQGGALTTHSAVLGEFPGPYPFHEEGALIDE
>C7S9W5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYVVDDFATRLLFID
SSHAGTSKGWLTDETIGWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLE
LVERFPSLTRIFCGHNHSLTITQYLQALISTIPGTVHQVPYCHEDTRSYYDLSPASCLMH
RQVGEQWVSYQHSLAHHAGPWLYDENISCPTEER
>A0A380AE29|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Shewanella baltica|TrEMBL
MRIVQVTDPHLFADPEAQLLGVNTGKSFDAVLNTIRAVDYPAHLMLATGDLSQDYSAESY
QQFVKAVTPVGLPCHYLPGNHDDPRIMYLHMQGEQIFGQQRILAGNWQILMLDSTVRGKP
GGNMAETQFELIDEAIAAHPECHTLLVMHHNPIVVNCTWLDQHCMDNGAEFIARVAKYPQ
VKGLLWGHVHQCIDTHHNGPHGSMQLMATPSTCIQFKPLSPYFALDSVQPGYRLLELKAD
GSINTKVYRVPGNHFSPDNNSSGY
>A0A2X0RCV1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactobacillus helveticus|TrEMBL
MKGKLFRKCKKTSQGKDLYYQETALTAFMRMAQRKKPAAIIVTGDITFNGERVSAEKFAE
IFKPLKHTQVLVLPGNHDIFDGWAREFRGKKQFYAGEISPMFWRSIFAKSYRQAFNTDDS
SLAYSVQLNPQYFLILADSNIYGTEETTAAPHTRGMIGKSQLKWIEKQLQYAEKINFVRF
YLCIIICMLIILL
>A0A2A2HF35|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Methanosphaera cuniculi|TrEMBL
MPIIEVTENHKQTITKSDMNDLTKTFRDRYTKLREIIENEQNITGNLYSVSEIINKADAH
KETKKTPKLNKYQLTNILTKNKQYLKNITSGKYTFKNIHENKVTLYDIRQKKDVIIDSYQ
RENLPILMKFYTYIQKAHSLKTITLLRHVKRTKKGNYILTCEDGTNTYDKYGYGKIDYIR
TFLTPEILKESGITPDTLIPDTVVYQEIKFIDYPILGTQLQRDKLKTIDIKQPSLQRKQT
HLTKDAHIVFLSDIHVGSKYFNETKLLNTINYINKSEVDAVLIAGDIVDGIGIYPEQEKD
LAIKSFHKQYEKLNEYLDQIEPHMYITPGNHDAVPLKEPQQPLTDQYAPDLCKNKNITLL
SNPSTVNINGTRIRMYHGKGLDDLIMAIKNLDYQHPCKVMEEQLEKRHLAPIYGMTTQHA
WEGEDKLVIDELPDIFHTGHVHIAQHTNYKGIELINSGTFQEQTPFQTTHKIRPTVGLIP
VLKDGKITMKQM
>A0A0M7HD91|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Alcaligenes xylosoxydans xylosoxydans|TrEMBL
MVRVHSLARRNDAPAMLVQLTDCHLFGEPETVMLGVNTDASLRAVLRQIEADGKRPDLLL
ATGDLSQDGEPAAYRRLAAMLGAAPALDGARIRCLPGNHDLPSALRQELPEWSTPVTDVG
AWRVISLDTTVPGSNAGHLPDSQLDLLEAALAEAPRRHTLLAMHHNPMQIDNHWHDSMMI
DNPQALFKLLTRWPQVRVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNLA
PGYRWIKLYQDGSMATGVRRVQDALWHTGAEPGPDSARAA
>A0A3M7RWT3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Brachionus plicatilis|TrEMBL
MILNSPGHKIFANVKPKIYQLLISLIKEAILATDVADHMDIRKDFSNLVRSKNVDWNEES
NKILLRKNLMTACDLASAAKPWKTHKSVVNQVIKEFFAQGVRERTELNIEPTEIMDERRS
DQLPRLQMGWIDAVCFPLYQNLALLCDSFNGHLDRLKENRLNWSLLNEKIKLSQIKEPNK
SHYLNGRL
>A0A2H6K2Q4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|bacterium BMS3Abin01|TrEMBL
MNPEATVSSSEKSGGITKDKPFVVAHISDMHAGSQYFVPNLMDRAVIELNELKPNVVVVT
GDLTNEGFKQEYLLAKSYLDKIQCENMLVVPGNHDARNVGYVHFEDMFGSRQVCRHRDGI
SIIGVDSSEPDLDYGTIGRHRYHWLKEQFETPANFRVFMLHHHLLPVPGTGRERNVVYDA
GDTLQVLQECGVNLVLSGHKHVPNAWRLENMFAVNAGTVCTLRLRGKVRPCYNVIEISDD
QVTVWRKYPFHDADQIIKFYPSTFAFEKSADQNKESSG
>A0A486VZQ8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFID
SSHAGTSKGWLTDETIGWLEAQLFEGGDKPATVFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQIGDQWVSYQHSLAHYAGPWLYDENISCPTEER
>M1WPH9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Richelia intracellularis HM01|TrEMBL
MSDTYPVSVAQITDIHLFADENQELLGIPTKDSFCAVIEHLGNLDTEIDMLLLTGDISGD
GSPESYENLQNLLYPLRLPTYSVPGNHDCSNVMKEVLNLKLFSRRKSFERGGWNFILLNS
CISEQAHGYLSIETLDWLDAQLTILDSKPTLIALHHPPFLINSQWLDKSRLQNPEDLFAI
IDRHSYIKLVICGHIHQEFQYQRYQVNYLSTPSTCIQFQPNSPDFTLDDKQPGFRYLKLY
SNGDWESWVERVPFLYPLNLSNTGH
>A0A086M5C3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii RUB|TrEMBL
VDADRCAQVHSGLTPELLIIQTFFLIVLDFAFCVRLRISQWLHLCAVSLLLSLAFVYSIL
LPLPAYLIASLWGQAVIGGFVLGSLHLAALTLETERRRVFLHFEVAKARVAELQERAQTD
KHHGKVAVFGLIHTLKQMDACMNELQNLAPEAADVLFQLDALRVQCLDIATSSENFYAVN
MNALPTDVRDLLQLETRNAFDGTTFRDTQVLLRDSLSPRKGVLLDLSLGPACGGVSRERR
ASCSAAVSSTSSRESDRREAIARDPDLTETERRDAERRGMERKATDDRQKKARFLVVPQL
VEHELLCHVGILWSLDLFKLDKECNGNALLHVGYQLLAPLLAAGYLTCSREVVLDFLYSL
QCLYIDTPYHNQLHAASVAHLAFSICHFLDLFAPLENAPGDAAASQPVFAQYLSLAIAAL
GHDAGHPGRSNAFLVQTSSTLSVVYNDRSILENYHACLTFYTLSHRKSNIFRGKTVTQYR
DVRKKAIELILSTDMSLHFEFLTRVAARRENPDFNFVDREEDRALVLSLAIKVADLGHCA
LDWEAHTLWSARLKEEFLAQGDEELRLGLPVSPLCDRTQQGQLARSQANFIEFLFLPLAQ
HLAAVAPDDRFEATVVTRARQNISMWEGAQDEVDQASAK
>A0A1V0PUN0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodovulum sp. P5|TrEMBL
MKLLQLTDIHLTTPGDTIAGRDPNANFERALAHALDRHADAEALFITGDLSDWGEAADYA
RLRETIASLPLPVHLCIGNHDDRATFVSVFPELEGEGGFVQKVVPLSLGHAIVLDTWGPE
THAGHFCEGRAGWLYRQLQSLPGPVWLFLHHNPVALGVPPMDEIMLLDAARFAATVEPFA
DKVRHIFHGHCHLPLSGSLHGIPFSAPRGTNHQGWPDFSATRMLSGSDLPESYSVIFATP
TTTMVHMVEFGYSGEIRVENTPDYADWDKQTMVR
>A0A086LKF8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii RUB|TrEMBL
MEERRLLKGNSQTPLKASDTQSTENELPLPKNLGGSSVHGRQSATTDAATHAPSIASVNS
KAASAEPSQCSPSGDAPSELKSILVNRQLKPRDADEDADTGKGPCFGPTQSQFFGTGHSQ
YSCWERFTDFMMPLWENEVNFVLKEECDKQAFADRDPRPIRSKPKFLSQ
>A0A086M4M9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii RUB|TrEMBL
MLCTAKLLQTMGGTMQILSSPSRGMLVSFQIRTRARFRLLDFQKDFRASFSQQRRQRIIS
LGLAPETSRALQFLCKDVGIQFTACYCLRHLRESLATETKTFSLAFVLGDFVTISANAAD
PASRPLTSAEIFREAQEAAALRPPPGCCLPLVKVFVSSRGDRSSQDGDEKVEARQHPLPD
DVTK
>A0A806TKW9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Priestia megaterium Q3|TrEMBL
MLGGFMETLKKDWLALVLISVLICGITLNVRAEEKSGRSGYIEPKLVFPVISDVHIKETG
TLDLRTFQHALTQLNEQAPKQDAFVVVGDLADTGALKEYDRFFSIYNQNKQSQAVSLFTI
GNHEYRDSVTNQQAQQRFLSKTKMKSLYFHQVIKGYHFIMLGTESRLTAGDYSIKQINWL
AEQLKIAKRDDPKKPIFVFIHQPINNTLYGKNRWGIEVNEQLLYNTLKPYPQVITFSGHT
HHPLDDPRTIFQRDFTSLATSSVRYIWPGAGYLQGELPPGYRDVSQGLLVEVYNRKVVVK
RRDFHANKWTGEAWEIDIPADTKKFHYTNERDLVKPIFLPSSTISVIQEKASANQLYIQF
TQAVDNLMVHSYRITVKNKETGKVVKTYNAFSQYYSDPVPDVLSLPLSGLQPHTAYQIEV
AAVDAFDNQSDQKLMIEGSTK
>A0A378K597|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Legionella pneumophila|TrEMBL
MKIIHISDLHFGKHQPAVLNAFLQETALDKPDIILISGDLTQRGLSYQYRELCSFINQLP
AQTLTVPGNHDIPFYNVPARFIFPFRHYKRYINSDVTTTFENDCVRILGVNSVNPLQLKD
GKLSHETLNRIEQYFKPDDKKLNLLFFHHNFDYMEGLHKPLANAQTLLSFLKQSTIHLVC
TGHLHYAHLSLIAKNNSYSCLALHAGSLLCPRSKDNLNSYYVIEANQKKCRITWRVFDQE
HFTARSIYFIDFNKKNASFEHINPVKDDTC
>A0A086QKY1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii MAS|TrEMBL
MHISCVKGRIVARQIDNVFTVIFAIEVLGKFVSYGLEYLQDPIESFDTIVVLTSFTLLVL
GFYVSGIGLLRILRLLSALALLHKYPDSKEKRPELSAGNSSKLEKASSIVEGLLTNVHIP
KYFKTELEWVWDSILANKVYDSHVVENEEEEEDQATETIIAGSDASRKTQAAVRASRAQS
RASKLPHGSSSMVVGTTNGRISGQILETLREPDPRMMDAALYKSETRNLDPLTATVGGMK
NSPSMFAKGSKSSNMMGSSASKSFRTERNKKAIDIISVLYQASQITGAEQEQVNEAMRPF
DEWQWDALHAGDVCDMNLLPVVFVRAIATFPTIMTKFNFDLDRLFDFLKVVQTSFQKNVK
FHCAAHTADMIQAMHYFLTIGKLGALLSEYDVFLCHFCALVCHFGHPGVTNTFLVKSRHP
RAIRYDDESVNENYVASAISCLVAREEYNFFGDKLPLWQVFRLHMIDILLNFDISKSAHQ
VAMFRTKVSIKFTASTPADKQLLLTILLRAADYSFTCRQLALYSKWKDRMIDEFFAMGDT
EKQLALTVSPFCDRELTNVDKCHVAFAEVAVKPLMTVLVLGLAPHLQKDVLDTLEANQKN
LMQKLDKSD
>A0A086QXD8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii MAS|TrEMBL
MLCTAKLLQTMGGTMQILSSPSRGMLVSFQIRTRARFRLLDFQKDFRASFSQQRRQRIIS
LGLAPETSRALQFLCKDVGIQFTACYCLRHLRESLATETKTFSLAFVLGDFVTISANAAD
PASRPLTSAEIFREAQEAAALRPPPGCCLPLVKVFVSSRGDRSSQDGDEKVESRQHPLPD
DVTKLSVPVRTDALIQILARALDSVEGCKSADDSSQEESEIEPEVPFMPGELVYASPRSE
GGKLAAGPGRKSLLVSCERSEANEASGKGGDSSPQKKKRNTFRISVARRRTLRASASPHS
QRESSVTSEAARHRNLLSSVFRGKDSPPRRSSRDTNDKASLSDDSKDKGESTSPLRRAKQ
RRVVKRTTIPGDARPREKKKRRTKRSGRHNETKEKENG
>A0A1V4IHV3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium chromiireducens|TrEMBL
MKAGLKFDANGNFKIVQFTDLHEGPNSDKGIDLMNKILQYEKPNLVVLSGDSIDGKCQSV
GDISKAISHIAEPMEGRKIPWAIIFGNHDDEHKVMSKEEMMKLYMAFDCNISEIGYKTFD
RIGNYNFLIQGSKENIPKFNVYMLDSGKYAPTFIGGYDWIKLTQACWYKRTALKLKKKYK
SIIPAIMFFHIPLKKFKEAWETGLIDGERHEDECCAKTNLGFFNKLVNTGDVKGVFVGHD
HLNNYCAELKGIKLGYAGYTGYGGYGEDDIPRGARVFLINESNPADFKTWLRREGDKELR
L
>A0A0D8HPC3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodococcus sp. (strain AD45)|TrEMBL
MSVRHAEYPRPKHFLVHISDTHLVEGGDLYGAVDATARLRQILAGVEASGARPRALVFTG
DLTDKGESDAYETLKSIVEPVAGRLGAEVIWVMGNHDDREHFRTRLLNESPSTRSVDRVY
DIDGLRIITLDSTVPGHHYGSISDAQLDWLRTQLATSAPDGTILALHHPPIPCIQDLAVL
VELRDQPRLAEVLRGSDVRAILAGHLHYSTTATFAGIPVSVASSACYTQDLNVAVGGQRG
RDSAQGCNLVHVYADTIVHSVVPLERDDVVRDDTVGEAVSARDAAARLADAGIRIGEHND
IAVAQ
>A0A091NET8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Apaloderma vittatum|TrEMBL
SRLRSLVKQLERGEASVVDLKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDSVPSE
VRDWLASTFTRQMGMMLKRTEEKPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIG
VLKNVDKWSFDVFALNDASGDHALKFIFYELLTRYDLINRFKIPISALVSFVEALEVGYS
KHKNPYHNLMHAADVTQTVHYLLFKTGIAHWLTELEIFAMIFAAAIHDYEHTGTTNNFHI
QTRSDSAILYNDRSVLENHHVSAAYRLLQDDEEMNILSNLSKDDWR
>A0A0D2KE76|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Monoraphidium neglectum|TrEMBL
MAELAPRVNSKNALVGTRLEQHIKHNVYDWEFDVFQLQRLSGGRPLFAVAMALLDREGLL
DGWLLDRPVVERFFTEAEAAYNGNPYHNATHAADVTQTSASIMRRVQQHLTRSSGGGQDG
DDSGRGQQQQQQQQQQQRRPGGTGLSQLERFAVIFAAAVHDLGHPGVNNDFLIRTRHKQA
LVYNDRSVNENMHCSRAFELALETEGCDIFRRFSAEEYAQARSLIVGMVLSTDMAVHFDL
MARYNTALEACPDVRLWGDKDRALLLQVLVHLADLANPARPFPLAAAWAERVVAEFLQQG
EREAEHGLPVSAMCDPARVTLPRAQLDFIRLFAQVGPRGAPWMRAASSER
>A0A095B4S7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sphingopyxis sp. LC363|TrEMBL
MLIAQITDIHIGFDPDNPAEYNRKRLDEVLDVLIEGPNRPDLLLATGDITDRGDDDSYRR
LVTAFSRCPFPVWPSVGNHDLRDNFHARFPGFDDGGGFVQYTIELPELRLVTIDTLEEGR
HGGAFCEQRAAWLDAELAKDRGKPTYIVMHHPPVESGIEWMNTHPDEPWVATFTDVVRRH
PQVRGLICGHLHRSVTVAWEGRTIAICSSTAPQVSLDLRPIDENKPDDRPMIVAEDPAYA
LHRWNGRELVSFYDHAGAHTMLAKYDERLQPLVRELKAERPGQ
>A0A4W6DPJ9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lates calcarifer|TrEMBL
LLKGVLEQMDRGVVDLQELRRNLELAAAMLDAVYTDETRRLLDTEDELSDLQAESVPSEV
RDWLACTFSRKMGVAKRRPEEKPRFRSIVHAVQAGIFVERMYRRTSNMAGLTYPPTALTA
LKEVDQWSFDVFSFHEATGDHALKFLVYDLLTRYDLINRFRIPVQALVQFVEALENGYSK
HRNPYHNLIHAADVTQTAHFLMLHTGLMHWLSELEILAMVFAAAIHDFEHTGTTNNFHIH
TRSEVAILYNDRSVLENHHVSAAYRLMAEEDMNILVNLNKDDWRELRSLVIEMVMSTDMS
CHFQQIKTMRNALTQTHGIDKVKVLSLMLHAADISHPAKAWPLHYRWTHSLMEEFFRQVL
CCSGIHEAVFRAVILRLTSSTLLTGEDVYDMQI
>A0A4W6D597|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lates calcarifer|TrEMBL
SVPSEVRDWLASTFTRQRSLILRRNEDKPRFRSIVHAVQAGIFVERMYRRTSNMTGFSYP
PNVITVLKHVDMWSFDVFALNDASGDHVCQQTVGYSKYKNPYHNLMHAADVTQTIHYFLL
KTGIVVSLLPSHDFEHTGTPITFIFRPDTAMLYNDRAVLENHHVSAAYRLLQNDDEMNIL
SNLSKDDWRELRTLVVEMVLATDMSCHFQQIKAMKGLLQQPEAIDKPKALSLLLHTADIS
HPAKQEFFRQGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEPTFTVLTEMIEKIVT
PLIEEASRSGLTGFRHSRPCTPTVQPHRCYHLSDLQFCADFSLKKNHKGINVTSMTKNFI
HNFDSRCQCRAIR
>A0A086LG25|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii FOU|TrEMBL
MWFYSYLRHPNDVPSLCTHIRSSNIFLRLGPQYYLPEDERKSLFVRTCHLLYYLASLLFL
TTLTTYTAIKIPSSPSTTTELLSQLFPFNSIDDCNERLSCKVDCVLYAFPDLNCAKDDGS
LLTFGGNSYSSLYFYHYPGKDVPLQKEARTAWERCYQIMRETTGRLQFLQQDRETVERTH
TCFAGCKTNGAVTFTQKLTDGTPVVFDSGTDWLQMAPAGSLPQDTRPACNPSEPPSLLCV
EPTDECQHVTLRYQVCIGDTAFCFDIVRILITIALGVVWNVVLDAFVVWAMSIDDSDPQN
LGRVASKCGLQIIATAIIVSSFFCLVASMTRILSMDANIARHGTLWTSFVLVIIIDQLFS
FLFSVLIWYAMLRRCGRQLPDESRFQYKIHPSPVLVKLKKATRKIVNYNGFEMFFTMLLG
WMVVDLTCRMILCQFFFDETAFLNQADRILEVVDFIILILFIVEICLRIAADGLKIYFSD
PINCIDFFLVFFGFGIRIVDFFIQINKGIGNVLFIMRLVRLYRLHRPPTGSLAIGKKEVF
TSRVERIIAVLNKALEIEELTTREKDSLKWLIQTISSGKLYEMGSEEKKKTDSHVQAWIS
IISTQSQSANQMADDMENILLERVKQMTKAGDAETDMPAVLQLEYGIDVSLDHAIEGYLA
NNLITWNFDVFRFHVIAGRAALPKLFVRCLQHQEVCSLFNLKIENMLRFAMELEKTSFST
TPFHNSIRSAEVLQAMHLFLAFFDTQIKGFFNSREILAALLAAVVWDYQHPGFSSAFLIK
TQHAIAIRYNDRNVLEHHHVAAAFSLMQKLGENDPLLAFPEDQYIALRKIIIQLSQSGSR
SNQTACLSLLKTKLQQAEFPRSITEDKNIILCNLMNAANYSFLGRPLQLYLQWSQKYMEE
LFMQGDRELELDMPITKNCDRHTTSEAVVQLGLIDGWAIPIYTTLAQTVPKLNAIVVSHL
RRNRLHWLDEQQEEDKSKEKQTKVTPIKRYSKTKQGSTEATGNGELSKPEATTIEIADGT
AGVPELRANANPLSEVD
>A0A378QVS0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moraxella equi|TrEMBL
MTYPTHLSTPSDFVIAQISDLHLSTHVPTNTDKFLKVLDFALTFKPNLLLLTGDLVNDGH
LPLYDWLFAALDKTNTPYLCLAGNHDVTHEIGHDLPFDKRTFLPIAKDDRLIDTHRLIID
LPHATWQLLAVNSALHGHIYGRLDDAQLAFLKTHLNHAMPTLIALHHHPTPIGSAWIDEH
MLQNGDEFWAILNAHTTNTAHRPHVLCGHVHQAHILQQNGGTLYTCPATSRQFAPHRDEF
GIDDVASGFRLLQLHNNRTLDTWVKRLDNSGF
>A0A3S4ZGP7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas stutzeri|TrEMBL
MPGASLTVEDSVLLVQLTDSHLFAEADGKLLGMNTCESLEQVVELAIDEQPRIDLILATG
DLSQDGSVASYQRFRRLAERIEAPARWCPGNHDELAAMREACRGSALMEPVLEIGGWRVV
MLDTLVAGSVFGMLRNDQLELLERALSEAPDHHHLICLHHHPVSIGSRWMDTIGLRNPEA
LFEVLDRHRNVRALLWGHIHQEFDHWRNGVRLLASPSTGVQFAPQSEDFQVDSVAPGYRW
LRLYADGQLETGVSRVSGIEFEIDYSVKGY
>L0B0K8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Theileria equi strain WA|TrEMBL
MQTPKKKRSDYDFYFRGVNNNFCPPTIDSSTYTCLSEPNIKDTIRYDDIKTKPFLNNQVV
NINVGGIRYTTTLSTLSRDKNSYLYKYVVGVIKGIDFSNDDKCFEGYVNISTVNPGDFIS
IFVDRDGNIFQYILNYLRNGELFVPDDLFIYQSILSDAKFYNITDLVNKVQRKIDGLTDV
PCDEVMVVYDKSNEPCPNQSQRTDFEPIDNVPISQLTNSEYSHPHSQNYFLTINETDNIE
ESCEFIQTTPLRSLGDVEFNTSADF
>A0A081RNF4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Marine Group I thaumarchaeote SCGC AAA799-N04|TrEMBL
MIIVQISDLHVGSQFLEEKFNVLVNEVNELNPDVIVITGDLTNEGLMKEYEKCKSLLEKF
NTKKIIAISGNHDYRNTGYLLFKKFFPFQTVNELSDDVVLVTVGTARPDRNEGEVGYRQN
LWLERTMKKFKDKIKIVAMHHHLIAIPDTGSDQLTVVDAGDVLRTVLDSKVDVVLCGHKH
RPWAWNFGTLTVVNAGTATSERVRGLFENTYNILTIENKKVQVDLKIVGGKRVPIDEIVK
NYSQFHDELDNV
>A0A3R7NEI4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Trypanosoma rangeli|TrEMBL
MPHKKNGLQRPALGKLSTAVLSAHYEEPEKGVREREGRCFGDALFMGHAPARSLLFADAT
SHCRAEKFNLQDNNPANWASIQTNLKRDVPLLQDPTETFGQMNRVMHQTLKYVKEVESID
FSSRDVTDFNGELMKDPRRVFLSVCTSVLANFSFSSQMDVEKLLSFLSSLFEGYATDNAY
HNALHAADSVQMLYLILREKPATLIFTDNEVIVAFLATLSLSFVHPGVSNVFLARIDHPL
VWVYGDITTQQSASLTAFLYHLNREENCFIKLFANSGTQPFSQFLRELLFETVLITAPRL
RDLLLHGLEKIAAANVVELEDVPLLLSAIIILADNALTLRPHAQFFNLAGCMVTEWLREA
YEEEQRGMDPIIPNLRNQALDNGLEMVVDYCKAWLVPLITAIRALVPQDLYDNMIGNTEA
ATMSDVTEFGGHLVSCNERWNDGSVPVIDIIRRVTMHATSLDRKASKRAILNASANRTVS
RFLSPLSLSLSPSEVRTFPDLAKRKPSHQTSRCEHYFSFLRLYDTYEKEGRPASEFAAQL
VFLALQLNREYIGSHTHEGVEVCSKKDCEEIAKLIMEKEEAPTTAEVIASPLRDGRQTDG
FILRLMEMYAERDRDRDRNEVPTSNFTLGLRRTLNCCNPVYGGNHTGKKP
>A0A378II29|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Legionella birminghamensis|TrEMBL
MKIIHISDLHFGLHRQEIINCFVKEVNEILPEIIIISGDLTHRARSGQFHDLRTFISRLP
GKVLLVPGNHDIPAFDVIQRFLTPFEKYRRFINNTLEPAYEDAKLRILGLNSVNPYSIKD
GKLSSSSLMKIERFFKVSDERLNILFFHHNFQHFEGLHRPLSNTRAFSEALKKSAVHLVC
TGHLHFANVSFLEKNQQESFALLHAGSLSCQRTRDGQNSFYLIEFEAGECAIKLMQYELS
QFKLKDSYSYSYRSALSQTIRPEELL
>A0A6J4HLZ1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Arthrobacter sp|TrEMBL
MEYRTAEHPRPQHFILHLSDTHLVGGPGPLYGAVDSEERLRRIFADLTASGARPDAIVFT
GDLADKGEPGAYEKLRAIVDPAAERLGAKVVWAMGNHDDRASFREGLLDEAPGTGPVDRS
YDVDGLRIITLDSSVPGHHHGALSRGQLLWLANELLTPAPHGTILALHHPPVPSVQDLAV
LVELRGQRDLAEVVRGSDIRAVIAGHLHYSTTATFAGVPVSVASATCYTQDLLFDGGGTR
GRDGAQSYNMVHVYEDTIVHSVVPSGQYTAVGETVPRAETRRRLEAAGVRIAEAAPARQF
SGV
>A0A315XNV6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Methanobrevibacter thaueri|TrEMBL
MTKILAISDVHGEENENLYTYLNNNDIDLVLILGDITDFGPLDFVETFINKVADCNVDVI
AIPGNCDPNGICNAINDVAFCLHNNIIAYGDAILFGFGGSNPTPFDTPGEMDDDKIYRQV
YDLLANYDYVYNSDIPKVKILATHAPPFNTAADRVENGEHVGSPGILKSIHEFEPQINLC
GHIHEAKSLSKIGKTTDVANPGMLKDNGAVLIDIIDGSNYDINIISLDE
>A0A0S4V680|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ralstonia solanacearum|TrEMBL
MVEMTAARGNKTVTVVQITDPHLFADRDSELMGYRTYPMLSKTIDAIRGHDFRPDACFLT
GDISQDESADSYELARFELERLGIPVFWIPGNHDDRGRAEAVFGQSERIHRLSKLTTADW
DFIHLETCRRGADEGYLSDPDFERFVSDVEASAGAGKQIAVVMHHHPVPTQTPLLDGYML
QDGERLLSFLDDHRQVRLVICGHVHGDYQLQYGSQTIEVCPATCFQWEKGTRTAKAEDWR
GFRIFEFSSAGYQSALISV
>A0A7R9J1Z4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Timema californicum|TrEMBL
MRWKGGCEERRLADEDDELSEVQPDAVPPEVREWLASTFTRQLATTRRKNDEKPKFRSVA
HAIRAGIFVDRIYRRVSNTALMQFPPEVVKVLKTLDDWSFDVFALSESATSQPVKYLGYD
LLNRYGMIHKFKVPPVTLETFLNKVEEGYCRHRNPYHNNLHAADVAQTVHYMLCQTGLMN
WLTDLEIFATLVAAIIHDYEHTGTTNNFHVMSGTDTALLYNDRAVLENHHISASFRVMRE
EECNILQNLSREEFREFRSLVIDMVLATDMSFHFQQLKNMRNLLSLAEPKSKALSLVLHC
CDISHPAKRWDLHHRWTMQLLEEFFIQGDKERELGLPFSPLCDRNNTLVAESQIGERFV
>A0A161UGI1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudovibrio axinellae|TrEMBL
MNAYTDRLLKLIVMSDIHLLPEGEVKRGLDTGPRFEAALDSVQALHMDADLCVFAGDITE
KSDVQAYERFDHMRSRIELPQRVLMGNHDDRNIYLTCASEPMLDENGFIEGFEDIKGHRI
LMLDSSEPGMTRGGLCRKRLTWVADRLAEAKAAGLKVIILLHHNPCALQMPVDTYRLAEP
DKLLAVLHRSDADIIQIVAGHCHITTAGSWGGYPCATISGNQHRVEPFLRGRSGQQACYE
GPAQYAVIQSDGTNCAVHYQNYVDHSTVMNPELFPGKMKQEFESLDY
>A0A653E0C5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas marincola|TrEMBL
MPSAPMSKTDSSVLIVQLSDSHLLEEEGGRLLGMDTYDSLQQVVDRVLQEQPVVDLVLAT
GDLSQDGSEASYQRFREVSSAIDAPARWLPGNHDEVPAMQAACVATHLLDPVVDVGNWRV
IVLDSSIPGAVPGYLGDRQLALLERALSEAPDRHHLITLHHHPVSIGCRWMEPIGLRNPG
ALFAVLDRFPQARAVLWGHVHQEFDQMRGNLRLLASPSTCVQFMPGSEDFQVDTTEPGYR
WLRLYDDGRLETGVSRVAGIDYVVDYSVKGY
>A0A3P6QM90|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Anisakis simplex|TrEMBL
MISTFISQIIISNSDKYTFKSYEETFSNFRLRYILHQLNSGQLPLEDLKKNIEYAALVLE
TAYMDETRRICDEDDDLAEVTSESVPDEVREWLAATFTRQNVPSKREKPKFKSVANAIRT
GIFFDKMFRKSQAVFAPIPPEIAALMRNVDSWSFDPFKVNEVSDGHALKYVGFELFNRYG
FLERFKIPYQTLENYLLALEAGYSKHNNPYHNIVHAADVTQSSHFMLSQTGLASSLTDLD
LLAVIFGALIHDYEHTGHTNNFHIQSGSNFAMLYNDRSVLENHHVSACFRLLKDGDRNIL
ERLTKEEYRCEFFHK
>A0A5P9F1C1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbulbifer sp. THAF38|TrEMBL
MIREHNKSDSPPGVTSQRLIQITDPHIGSRPDYQLLGLDTGYTLDEVLTSLRSGLPRARA
LVATGDISANGSEASYCRFLEKTRTLPMPWYWLPGNHDVSARMKKLAPNRCTDLVALGDW
RLLLLDTSVTGQICGGLDSAQLERLQLLLWETRDHPVIIMMHHQPVPVGSKWIDGHMLRE
GCETFLQMVDQAPQVKALVWGHVHQQFDSNRGHFGLHATPSTSVQFTPGSGPFAVDDEMP
GYRWFELFSDGTYETGVERVAISKYCVDLASSGY
>A0A150HF96|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium laevaniformans|TrEMBL
MRMAEHPAPERVLLHLSDTHLRAAGSRIWDRVSGEEHLARALSGIEASGVRPDAIVVTGD
LVDLGERAAYATLRAMVEPVAARLEAPVVWVMGNHDDRAAFRSELWDDEDADLRPVDRVD
EFDGLRIVTLDTSVPGHHYGEISDAQLAWLATVLVTPAPLGTILAMHHPPVPSVLALAAS
VELRDQARLARVVRGTDVRAIIAGHLHYSTFATFAGIPVSVASSTCYAQDLTVPVGGTRP
QDGAQSYNLVHVYDDTVVHSVVPVDVSRVMEYTDPEAAQRLLADAGITGVGVQRPSAPPT
RPVSVLH
>A0A654SB63|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chrysosporum ovalisporum|TrEMBL
MDQVSPLSIAQVTDTHLFASENEKMLGMTTIESFQAVVERLKQLKSELDLILLTGDLSGD
GKPESYDILQSILNSLQIPVYWLPGNHDCAIAMSDTLNVGMVSRRKSFKRGGWNFILLNS
CVAGCLHGYLSGKTLDWLNSELKTLGDAPTLVALHHPPFAVNSAWLDSTILKNPREFFAV
LDHYPQVKLVLFGHIHQEFQHRRYEVSYLGTPSTGLQFRSQTPTLTIDKQDPGFRLLKLY
PSGMWETVVERVPYVNPYVNPLGLAAKAGELAILP
>A0A2H6J1Y3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|bacterium BMS3Bbin10|TrEMBL
MLIAQITDTHLKSGGKLAYGKVDTATALSNSVTHLNALTPRPDAVIITGDIADMGRPEAY
ALFREIVSGLAMPYYVIPGNHDETLAFCDAFRDHAYLPSDGRFLHYAIEEYPVRLVGLDT
TVRGKPHGLLCAERLDWLDQTLTEFPEQTTLIFMHHPPFLTGIAHMDRQNCRNAEGLAEI
VRRHRQVVRITCGHVHRPMQTLWAGVAAGIAPGSSHSVALDFNPDGLPAFVLETPACQLF
YQTEDGNLASHLSFIGDFEGPHPFFDKFGALID
>A0A1S8MP49|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium saccharobutylicum|TrEMBL
MRIPLKFDSYGNFKIVQFTDLHEGPNKDKAIETMNKILEYEKPNMVVLTGDIIDGKCQSV
DDVKLAINHVAEPMETRNIPWAIVFGNHDDEHNMMSKEEMMKFYMNFKYNVSQTGYKTFD
RVGNYNILLEGSKENAIPKFNLYFMDSGKYAPRFIGGYNWIKFTQICWYKKKALNLKIKY
NKNIPALMFFHIPLQEFKKAYKNGVINGKRFEEESCPKINSGLFEFIYNVGDVKGVFVGH
DHLNNYCSVFKEIKLGYGGYAGYRTYGEDYIPRGARVFLINELDPANFKTWVRQEGDSEL
NL
>V6AMQ0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas aeruginosa MH27|TrEMBL
MSRHSNTPATDASVLLVQLSDSHLFAEDGARLLGMDTAHSLEKVVERVAREQPRIDLILA
TGDVSQDGSLDSYTRFRRLSAPLAAPLRWFAGNHDEREPMQRATEGSDLLEQIVDVGNWR
VVLLDSSIPGAVPGYLEDDQLDLLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGY
RWLRLHDDGRLETGISRVDDVVFEVDYDTAGY
>A0A0F8C4D2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Larimichthys crocea|TrEMBL
LKEVLEQMDRGVVDLQELRWNLELAAAMLDAIYTDETRRLLDTEDELSDFQAESVPSEVR
DWLACTFSRKMGVTKRRPEEKPRFRSIVHAVQAGIFVERMYRRTSNMAGLTYPPTALTAL
KIPVQALVQFVEALENGYSKHKNPYHNLIHAADVTQTAHFLMLHTGLMHWLSELEILAMV
FAAAIHDFEHTGTTNNFHIHTSIDKVKVLSLMLHAADISHPAKAWPLHYRWTHSLMEEFF
RQGDKEVELGLPFSPLCDRKATMIAQSQIGFIDFIVEPTFSGLIDTTEKVIGPLIEEDRR
ARETGNRRSRYHYYYYYFYWGKVITK
>A0A086L528|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii p89|TrEMBL
MNASSKSMRIGFPNGSPGVGDPGMPSPVLPLCQTASHALGNARSQASEGRTDGASDRSIS
ELEKESCQRGHRLEAREASEILAAESAQEEHRSCARKPRASRVEVDTLAESPERPSQAYV
PTESLGLGPRRTVPLSSAGSSASAGSWISSGESVREETRQIRGRDAANKCSAAELSVSVE
RSCGHHEGTDTATQCVAARPEALCAAFLPAPSPGVTVDSAAAAVGPHCAAEVPVGADRRR
RLFAAPFSALPQTDACSRGSATPPSLFSRQPFDTVRSSSSLRDGGNAWTRLLDGCSAHPT
SSSSSVSPPVLGSIRTLQQSLPSSDDDTTSARTDTSLTPAKQVWLLPLHGHSLSQSSSSS
FREFRVTLGSLTGFRSSDSRTSASGSERRRSKSRGKPQGRSGSLGRDNRRKSELSGRDES
LSWIARRWWTRDEDSRWSDSRVRGSVALRAESTSDSRCENNSCATWLCRVVRRLPVAPAQ
TFCDEDEKRYTEGVLRFSRRRTIPVAVAVVIVSFLYTVPFVLHALQEFVQTPSADRKVFV
FFSSRAPPRSPVAAGAAHDAQLDVSAADSALQDVGGKDAFFVVASLVFWLLSLASVLVFA
FFAVFGALFVRIEKILCVLTAVNFSALALAECFQALRISSCPPSLFPEQAAAEGGSDADR
CAQVHSGLTPELLIIQTFFLIVLDFAFCVRLRISQWLHLCAVSLLLSLAFVYSILLPLPA
YLIASLWGQAVIGGFVLGSLHLAALTLETERRRVFLHFEVAKARVAELQERAQTDKHHGK
VAVFGLIHTLKQMDACMNELQNLAPEAADVLFQLDALRVQCLDIATSSENFYAVNMNALP
TDVRDLLQLETRNAFDGTTFRDTQVLLRDSLSPRKGVLLDLSLGPACGGVSRERRASCSA
AVSSTSSRESDRREAIARDPDLTETERRDAERRGMERKATDDRQKKARFLVVPQLVEHEL
LCHVGILWSLDLFKLDKECNGNALLHVGYQLLAPLLAAGYLTCSREVVLDFLYSLQCLYI
DTPYHNQLHAASVAHLAFSICHFLDLFAPLENAPGDAAASQPVFAQYLSLAIAALGHDAG
HPGRSNAFLVQTSSTLSVVYNDRSILENYHACLTFYTLSHRKSNIFRGKTVTQYRDVRKK
AIELILSTDMSLHFEFLTRVAARRENPDFNFVDREEDRALVLSLAIKVADLGHCALDWEA
HTLWSARLKEEFLAQGDEELRLGLPVSPLCDRTQQGQLARSQANFIEFLFLPLAQHLAAV
APDDRFEATVVTRARQNISMWEGAQDEVDQASAK
>A0A6N3D1V7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Enterococcus faecium|TrEMBL
MNILHISDIHFRREYEACEEGYKGMLATMQNPLIHLEQCIHHLLQQTPLDLVIISGDLTE
DGEIDDYRYLKTWLENALGETTILVTLGNHDIKEHFWVGWCDEAASSAPYNQIVKYPEFT
VISFDNSSYGYADGIVDDQQFQWLKKALEQEKDQPIFLVTHHHLLSHQSSIPKWPGTERF
LKLIAPYDIRCILNGHTHHTFTDEINGIPYFTVSSMSFVGEDEGDGFVRFEERHGYNLYH
LDQGRIVRQTTENFIPGNILKTLQMKD
>A0A238J6P1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pelagimonas phthalicica|TrEMBL
MKILQFTDIHLTRQGDTIGGRDPNANFAKALAHALDLHGDAEALFITGDLSDWGDEDDYA
RLKSIIADIPMPVHLMIGNHDDRQLFTSVFPELGNEDGFVQYAVQMSLGTALCLDTWGPD
THAGHFCEDRARWLTTQLEQIDGPVWLFMHHNPVPIHVAPMDKIMLLDAERFGATIAPFA
QKIRHIFHGHCHMPLSGSLHGIPFSAPRGTNHAGWPDFSATRLLASAELPESYAVIFATP
NSVMTHMVEFGYAGEIKGEGTPDYADWDRMTMVR
>A0A0M6ZMZ7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseibium album|TrEMBL
MKLLQLTDIHLTAPGETIGGREPNDNFRKALGHALTHHPDADALVITGDLSDWGDRADYL
RLKETISGLSVPVHLCIGNHDERDVFVSVFPDLVDDNGFVQSVLDLPLGQAIFLDTWGAN
SHAGYYCETRRSWLDERLNETAGPVFLFMHHNPVPTGIAPMDKIMLQDAEEFGNVIEKHR
AKIRHIFHGHCHLPLSGSFHGVPFSAPRGTNHAGWPDFANETNLSASDLNECYSVILASE
TSVMVHLVEYGYQGEVRREGSPDYADWNRLTMVR
>A0A3P8D8W3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Heligmosomoides polygyrus|TrEMBL
MVRKADSVCNERQFDNTAAIDTVEKKMMLVGDTFGFYQLVLRKHSCRLRYILHQLNSGQL
PLEDLKRNIEYAALVLETAYMDETRRSCDSPTHDPADKLDMYSTILSATRSAHEAPSRER
VREWLAATFTRQNAGKKREKPKFKSVANAIRTGIFFDKLFRKQQSVQCPIPPEIAELLRE
VNSWSFNPFQLNEVSEGHALKYVGFELFNRYGFMDRFKIPLVALENYLHALEQGYSKHNN
PYHNVVHAADVTQSSHFMLSQTGLANSLGDLELLAVLFGALIHDYEHTGHTNNFHIQSGY
VAVCRRLCSCALRDLSSYVMKVVLCHIALTTAFEESKN
>A0A3S9LSW2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli|TrEMBL
MSDPVRITNPGAESLGYDSDGHEIMAVDIYVNPPRVDVFHGTPPAWSSFGNKTIWGGNEW
VDDSPTRSDIEKRDKEITAYKNTLSAQQKENENKRTEAGKRLSAAIAAREKDENTLKTLR
AGNADAADITRQEFRLLQAELREY
>A0A2N7QQ19|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Dyella sp. AD56|TrEMBL
MFHETTGTGAGEGVSSAQGALVNFIHLSDLHVGISSAGWLWPAIRSAFLADLRVVLHEAG
PPDVVVFSGDLAQKASEQEYLELRDILEELWRVFAEFGANPVLVPVPGNHDLLRRPGADP
VVLAMKEWWSRPEVQEAFWDPKIPAYREFVEQSFKNYQAFCDSLASSSVRVPENIKRGVV
PGDISVELNVRGNIVGIVGLNSAWLQVNDEDYKGRLHIDPRQLMGVVDGDPDGWCRRHAA
NFVVTHHPTSWLHPESERAWRAEIHCGARFDCHLFGHMHEPQSISVSEGGHEGRRLIQAA
SLFGLEWIGNQRAKRIHGYCVGQLFLSDQKRRLRQWPRHDVLGTDGVRKVVPNLQFNLTD
YRYFDIDYSGIVEEPRASQTSTDISIYSDRKALDTLRRTLPSSEAARYVRKIEQETCLES
LEKRRLVWIASDWGLGADEFLAELVGKSSGGNSSVYQLDLGAYGSREEMLAGVRRDFGLT
FQQLCECISQEPDCFLVFDDVVLEDDSRATDNSYLLAISEIAEGVLEYCPNVRLVIRSRR
NPVQTKINVVELTSLDDVDAMIYIKNHPRGGRDLATDNFVRKICSYTDGMPSRIDSALDD
VQVVGLEGLHLANPDVSGKAALHLPPPPGLAETIAKLEQSDDPGALRAFRLLAVLSMFPR
GEYLESVRRFDGANPFHPQDARRLIDLALVDTGEITSIGGSESAGSAKALIVRRPVREFL
IAHLSPETVQRLNRQALSLYFGANWNAGAIKPPRDARFDERSCENWKIDNATLLVMREAS
EAIAAGVNTRISSAATLAQSFCIALMNGDHFGGLITAARELLAIYKDVSGHDSRLDLIKS
MLGRALRMSGYWDEARNVLKELGDSGLPKAMKRKNLLNLAMSSESLGEIDDAKLYAKQCI
ELDKNSREAMHSKAIILEQTTVNDPDRKAKLLRLAQAARRRKCNVLANNLLVTCMNESDD
AAEWHSLAEQVIANAAEHDDQHNAMRVVLRLCQRTVSKNQPLEMADLSRVIEAYQYLLNE
SMDPLFGMAHKVLWKHFSLVGDTENLLRLFRYSSFKWQLRGRSGADLEYAAEVIGLLGDK
LRSGFIRSTREVAYLIVRSGHTMKLLPSS
>A0A834AIL1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Phyllostomus discolor|TrEMBL
MHGRRKKILCFEIDCKWSTGKSKSPKPKTRKKVKADIKRLLDTDDELSDIQSDSVPSEVR
DWLASTFTRKMGMMKKKSEEKPRFRSIVHAVQAGIFVERMYRKTYHMVGLAYPEAVIVTL
KEVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLIAFAEALEVGYSKY
KNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILALVFAAAIHDYEHTGTTNNFHIQT
RSDVAILYNDRSVLENHHVSAAYRLMQEEEMNVMINLSKDDWRDLRNLVVEMVLSTDMSG
HFQQIKNIRNNLQQPEGIDRAKTMSLILHAADISHPAKCWQLHHRWTMALMEEFFRQVHL
SHSANVFGNSGCVC
>A0A139Y673|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii ARI|TrEMBL
MNASSKSMRIGFPNGSPGVGDPGMPSPVLPLCQTASHALGNARSQASEGRTDGASDRSIS
ELEKESCQRGHRLEAREASEILAAESAQEEHRSCARKPRASRVEVDTLAESPERPSQAYV
PTESLGLGPRRTVPLCSAGSSASAGSWISSGDSVREETRQIRGRDAANKCSTAELSVSVE
RSCGHHEGTDTATQCVAARPEALCAAFLPAPSPGVSVDSAAAAVGPHCAAEVPVGADRRR
RLFAAPFSALPQTDACSRGSATPPSLFSRQPFDTVRSSSSLRDGGNAWTRLLDGCSAHPT
SSSSSVSPPVLGSIRTLQQSLPSSDDDTTSARTDTSLTPAKQVWLLPLHGHSLSQSSSSS
FREFRVTLGSLTGFRSSDSRTSASGSERRRSKSRGKPQGRSGSLGRDNRRKSELSGRDES
LSWIARRWWTRDEDSRWSDSRVRGSVALRAESTSDSRCENNSCATWLCRVVRRLPVAPAQ
TFCDEDEKRYTEGVLRFSRRRTIPVAVAVVIVSFLYTVPFVLHALQEFVQTPSADRKVFV
FFSSRAPPRSPVAAGAAHDAQLDVSAADSALQDVGGKDAFFVVASLVFWLLSLASVLVFA
FFAVFGALFVRIEKILCVLTAVNFSALALAECFQALRISSCPPSLFPEQAAAEGGSDADR
CAQVHSGLTPELLIIQTFFLIVLDFGFCVRLRISQWLHLCAVSLLLSLAFVYSILLPLPA
YLIASLWGQAVIGGFVLGSLHLAALTLETERRRVFLHFEVAKARVAELQERAQTDKHHGK
VAVFGLIHTLKQMDACMNELQNLAPEAADVLFQLDALRVQCLDIATSSENFYAVNMNALP
TDVRDLLQLETRNAFDGTTFRDTQVLLRDSLSPRKGVLLDLSLGPACGGVSRERRASCSA
AVSSTSSRESDRREAIARDPDLTETERRDAERRGMERKATDDRQKKARFLVVPQLVEHEL
LCHVGILWSLDLFKLDKECNGNALLHVGYQLLAPLLAAGYLTCSREVVLDFLYSLQCLYI
DTPYHNQLHAASVAHLAFSICHFLDLFAPLENAPGDAAASQPVFAQYLSLAIAALGHDAG
HPGRSNAFLVQTSSTLSVVYNDRSILENYHACLTFYTLSHRKSNIFRGKTVTQYRDVRKK
AIELILSTDMSLHFEFLTRVAARRENPDFNFVDREEDRALVLSLAIKVADLGHCALDWEA
HTLWSARLKEEFLAQGDEELRLGLPVSPLCDRTQQGQLARSQANFIEFLFLPLAQHLAAV
APDDRFEATVVTRARQNISMWEGAQDEVDQASAK
>A0A174VB05|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bacteroides caccae|TrEMBL
MLNKNLFTLLSCLLLTGCGMIDYHPYDVRISGETDVNAHNIEQIEADCKGKKTIRFVTMG
DSQRWYDETEDFVKAINKRNDIDFVIHGGDMSDFGVTKEFLWQRDIMNGLSVPYVTLIGN
HDCLGTGAETYKAIFGPTNFSFIAGDVKFVCLNTNALEYDYLEPVPDFTFMENELTNRTD
EFNKTVISMHARPYTDVFNDNVVKMFQHYVKQYPGIQFCTAAHTHHYRDDVIFDDGIHYV
TSDSMDKRTYLVFTITPEKYEYELVKY
>A0A0M9I5I0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bordetella pseudohinzii|TrEMBL
MPQNPLAARRHEAPALLLQLTDSHLMDDPEALMLGVNTDASLRAVLDLARRKEARPDLML
LTGDLSQDGSPAAYRRLRAHLADASHPVRCLPGNHDAPRVLRQELGDWAQPVHDLPGWRV
ILLDSTVPGQDLGHMGEAQFALLDQALRDADNRHVLVALHHNLVRVDGNWHDPMMVDNAS
AVFARLSSHPRTRIALWGHIHQEFDCRHHHLRMLGTPSTCFQFMLRNGRHAIDPRAPGYR
WIKLYADGSIATGVRRLDAGTWAALRGQAAPEARAA
>A0A021X4Z9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Shinella sp. DD12|TrEMBL
MLIAHISDFHVFSDKPETPLVRLDAERVARRVVADLAAFAPRLDAIALTGDLTDAGSAQD
YALLQDILAPLSMPVFVVPGNHDRRYALRAAFADRLPFSDSSYLNYETRIGGLKVLALDT
LIEGRGDGALVPESLVWLAERLPAGGTEPALVLLHHPPFPSGIQSLDKAALTAGRSEIAR
LVREYRGPLTILAGHIHRPFQATWNGAHCAVAGSPAFQMALYLTPTPHEPSLVSEPYAYY
VYRFEDGNVAVHTRYVYLDD
>A0A1S8TN87|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium sp. BL-8|TrEMBL
MALYTISDLHLGFNVEKPMDVFGDRWKDHCDKIKKNWLNKITGEDMVLIAGDISWSLKEQ
DSKYDLDWINELPGKKIISKGNHDYWWGSISKLNKMYENTKFIQNNFYFYEDYAICGTRG
WVCPSGDKYTDKDEKIYKREQIRLKLSLEEAKRNKFEKIIVMLHYPPTNEKFEESEFTKI
IKEYSVQKVIYGHLHGPVLSGKVLDGYLDGVEYILTSADYLDFNPKRIL
>A0A1V6D7F9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Planctomycetes bacterium ADurb.Bin126|TrEMBL
MTSFRPALHALALFLALCSPSRADVTFIHWSDIHCNEDSGAAVKQGIVDDLNALGDKAWP
KQAGGEKVGAIDFVIATGDLTDRGTAPQWEQYLALRSRLRFPSYEAMGNHDIRGGRAVED
ALVKLHGATHYSFDKGGVHVVVLNPYVHRTRLPDFRKPQLDWLENDLAKVRKDVPLVLAM
HSPPLRNGSHFLTIGDSVDRFVSLIRGRKAIILHGHRHRCEKHRLDNTWLVLGAGKSAQG
IKRDSTCNVLRIRTAGGGRVTCAPYDWVDRKWSTKGETFLSDAPILPDEPSPRAAKGPDR
>A0A1S8TD42|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium sp. BL-8|TrEMBL
MTLFDQSFADLQVIKSKRNPNNYNIVFFGDSWVQRSTGSDIRFVSNDIFEVAMQRAMDFN
PLLFAYGGDGDFTGTEDNLNFLVEKIKSLNKDKNGDRVPFFMVPGNHDAARLGTTLSLDN
YKNIIGPEDIHWSIDLPSFRLRMVGLNSLYHYVYNEYGLTENELEFLANSLSDVRCSTNV
FVTMHVPPREPELNWVGDDAFPNERGRRDFYKIVRNRVSSVLIGHIHDFQLAKAHDVKFI
LSGGGGATLNVGARFHIVVINIQNHGNYSVVTPQLVPVGWQRATEPVSP
>A0A517QNR1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thalassoglobus polymorphus|TrEMBL
MGLRAGIDDEAKMMVCSPFKRPRDVLHKKADVLPIHLTTLNRRRFLQAAGASILLYGNNA
PASEAVDSDLVYLLNDTHIGEKHPENSAVPTHLRQVVTELVNRPTKPACVLINGDLALKD
GQPGDYRHFAKLIAPLQKAGVETHLTLGNHDHRNVFYEILKEQRPEMPPVKSRHIAVVET
QHANFFLLDSLQKTMVTQGTIGTQQLEWLASALDGLQAKPAIIVAHHNPRLGGDPLHFPG
GLIDSQELWNVIGPRKWVKAYIHGHIHDRSYAEHQGIHILNTPATSYVADPKKSTTGWTT
AKLTPNGGTLTTYTTDAQHPWNGESKTLTWRTA
>A0A4P2PZC4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sorangium cellulosum|TrEMBL
MELRVIGCHGGETPRHRTCAFVVDDVLAIDAGSLTSGLEVTEQARIEACLVSHAHLDHIR
DLATLADNRCQLECPPLVIAGTRETLRTLKKHFFNGVLWPDFAVIPTPAQPTIKYLELKP
ERPTVVAGRRVRAVSVSHTIDAAAFVIEGSGGAIAYSGDTGPTERLWEVLNQQQDLRALL
MEVSFPDREQRLATVSGHHTPRTLGAELMKYRAPRDLPTMLYHIKPVFQAEVERECAALK
GLNLEVLQLMDHFVL
>A0A0Q0HEZ8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudoalteromonas sp. P1-25|TrEMBL
MAWFDEHYHFNTSSLRVAHITDSHLFADPNAEYFNVNTAAHFAQALAHMATQSLDAVIFG
GDLTQDHSFESYLLFAELINNADLTCPVFWVPGNHDEIVMLNRISGGQIVSAKRILAQGF
ELLLINSKGPTPAGWVSSEHLNEITEYLASSQSQHVVFCHHNPLAINGYLDKHMLENGPQ
LLNVLVNSGNVGGLFHGHVHNQYMQTFRGLSIYATPASSVQFTKNSPQWHQENLGPAYRM
LHLTKQDNALTVKTDVVWLNA
>A0A1R4EER4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Psychrobacter pasteurii|TrEMBL
MSTFQGFIDPKTYPPTQITTADGVINILQLTDPHLYLDSDTETVGINNYKSFTACLQQAL
EEDIRCDLILLSGDLVNEVKPEIYQNIYQLLEKTGIPFVCIAGNHDVTDELYSHLPFSER
RFVAHKPNALLLSRHRLTLNDWRLLLIDSSVPGKVYGTVGNKNLNWLSQNVANSHHPVII
GMHHHVLPIDSAWMDDHITQDAEDFWQLIEDKPSVKAVVTGHVHQNFEAQRAGVKVYATP
STCYQFKPKSDNFAFDDQAAPGYRWLSLNKQGVIQSWITRLENKKP
>A0A1S8L2C7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium roseum|TrEMBL
MGLYAISDLHLAFNLNKPMNIFGEDWSNHDEKIKKNWIDKIKEEDTVLIAGDISWSMDME
NGEEDLNWIDSLPGKKIICKGNHDYWWKSITKLNNMYSTISFLQNNFFKYEDYAICGTRG
WIDKSFDNFDEHDKKIYKREIIRLRLSIDAAVKKGYSKIIVMFHYPPFKDESSLSEFTEV
LEEYNVEKVVYGHIHGPALKNVQGRISKNNIEYILTSCDYIKFNPIKII
>A0A1E3H0E7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Methylobrevis pamukkalensis|TrEMBL
MALKLVHISDIHLDPAPILGHDPEENFARCLADILRDHGDADRIVITGDLTHRGRAESYA
RLAAMLEDSGLAGDRAPRLLIGNHDDRETFVSVFPQTPRDGDGYIQWTEETPAGVFVYMD
TAEAGTHAGHYCARRRAWLDAQLSAAARDGRAAYLFLHHNPGVIHVANADRIGIVQQPEL
LALLLAHRDTVRHLFFGHCHYTLSGSLRGIPFSAPRSTCHVCWPDFSGIADRMGHGALAP
NYNVCFVDDEGVVVHSIDFLDAGKVRWLED
>A0A7H4NRZ8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella michiganensis|TrEMBL
MVVSGDIVNCGRPEEYEVARQILGSLNYPLYLIPGNHDDKALFLEYLHPLCPQLGSDAQN
MHYAVDDFATRLLFIDSSRAGTSKGWLTEETIKWLEAQLFDGGDKPATVFMHHPPLPLGN
AQMDPIACENGHRLLALVERFPSLTRIFCGHNHSLTMTQYRQAIISTIPGTVHQVPYFHE
DTRPYYDLSPASCLMHRQVDEQWVSYQHPLTHYAGPWMYDENISCPTEDC
>A0A4Y1N4E1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseomonas mucosa|TrEMBL
MELCETAFRRHESTLDRDRRANVDALTGLANRAAYNGAMAQLRCDDVGSWALFIIDLDNL
KIVNDTFGHLAGDALIRAASARIARAMAPDVTYRIGGDEFAVILQQPANVADLNAAAERV
FDELEVAADCDGHTVVPRATIGGATLSKTERTATSVGEAADFALYHAKETGRGGFVRYWP
GIGSRITSRRAAIRDVSEALAEDRIEAHYQPILRLDTGLIVGLEALCRLRSRSGDLLPAG
SFHEATTDAHVASELTARMMAIVADDIGHWQNAGLLVEQVSLNVSTADFYTGSLAKKVSE
TFSKAGIGLNKIVLEISEDVYLGRNDRVVAREIEVLRAAGVRVALDDFGTGYASLTHLVN
VPVDIIKIDRAFVARLWPDDPSTIIVEGLIEIARRLGVAVVAVGIETEVQASQLWAMGCA
LGQGYAFAYPAYRDATGTLLYRHAATGAGTSPLYPDRPTPLPSERISRRRTSVA
>A0A806ICB4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactiplantibacillus plantarum ZJ316|TrEMBL
MRPLQVIQISDLHLTPRGQVPAHGQQYDPWGKLANIIDDIRRLPTMPDLIVFTGDLIHDG
SADDYQRLHAIIHTMEAEFDCHVRVILGNHDRRAAFYEGYLPADPGPYYASRMRIGNNDF
YFLDSKVSGYEAGWLAPQQLQWLGKHLRQAPTKRAFLFLHHPLDGPTMTNMHYAILQNTP
ALLSVLRGHNLGGVFSGHVHFVSSYLIGDNILNVVAGSAAYAIDCHDPHHHYVHEGSSYQ
IITIDRGQVGVTTRQLLHGKAVIDELTIPDTKFVGRAPQGYE
>A0A1U7M3K3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Tissierella creatinophila DSM 6911|TrEMBL
MRILFFTDSHIRGTTPKNRKDDFTNTLEKKFNEIVEIIDKENIDYVIHGGDLFDRPDVSI
SLVSKFSKILNEIKVPIYIISGNHDIFGLNPKTLNRTMLGLICELKVLNIIDTNEKIILK
KDKVKVQLTGQPYTYNIDDSNDKSPYIVKDIEPGCDFSIHVVHGMLLDKPFIKGIPYTLV
EDIKETLADITLSGHYHSGFEKVKIDGKYFLNPGSIVRVSNSLREIKRKPKVAIIDLEKD
LNISYKYLSTALDGEEVLDRKEIENSIYRRERMYEFKQTIDNAMNFEKIDINDVLMGVSN
AEKVDEKVKKEALKRISLIQMRNMTGE
>A0A086QFG6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii VAND|TrEMBL
MLCTAKLLQTMGGTMQILSSPSRGMLVSFQIRTRARFRLLDFQKDFRASFSQQRRQRIIS
LGLAPETSRALQFLCKDVGIQFTACYCLRHLRESLATETKTFSLAFVLGDFVTISANAAD
PASRPLTSAEIFREAQEAAALRPPPGCCLPLVKVFVSSRGDRSSQDGDEKVESRQHPLPD
DVTKLSVPVRTDALIQILARALDSVEGCKSADDSSQEESEIEPEVPFMPGELVYASPRSE
GGKLAAGPGRKSLLVSCERSEANEASGKGGDSSPQKKKRNTFRISVARRRTLRASASPHS
QRESSVTSEAARHRNLLSSVFRGKDSPPRRSSRDTNDKASLSDDSKDKDGSDDEPVELFP
LHNETLQPLFPGGDQIPEPLLFDVNSVVQAVNQVGLSRPAEQLAAAIAQTPFQKDLDASA
KFIDALDSSLALLRYYQTLPGRDGSLQKRRRSRRMTDLDPQGTDRTWRPESKRKDPLAMM
QSLSALQVKVPAEPEVQAFFNLASSTLSVEDPISIHQVLNWDFHVLNLTPSTATRIA
>A0A1V5TIZ7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Firmicutes bacterium ADurb.Bin262|TrEMBL
MKIRPRKLLCVLMSLLLCLPLAGLFGAAGEEPLTVFVASDLHYRPPGMLAPIGEQTGLPG
DPLYWHTNIQGQLEYESDAIVNEMLRRFESSPAKALLIPGDLADSHIGYHLALAEKFRLF
ERRTGKKIFVINGNHDVKDNADGFTTDLARFKAAYAGCGYSEALAADPGSASYTADLGGG
YRLLAVDSCVYGTSDGEINAQRLAWIESQVAAAKTDGVKLIGMMHHSILEHFKIQGLVAD
TVKDYRALAERFAGWGIKVVLTGHKHANDITCAVSASGARIYDIETNCLINYPNTYRVIN
FSDNEIQVTSGYIDRIDLADLPPGYNGAQLELLANDFPAFSYGYFKAAMQRYVNEYAGTP
RKLAGSLNIREGTPAYEALAAVMGVLGGALSLPLYDTAGTPAIDSVEEIAAAGGENIAAS
GYARFSDLVALIVSRMFAGDENTPYEAPEVQLLLQAVKAGLVYAILNIPDASASALFAGL
GVPGAALKPGRAAYAAAAKLLFAKTAANKILAAAVKPLVEGITVDSFSPADLNVTLEGYA
ASGAVCEHGDPLSGPQVLLDYLNRFLNLLLSLMAALAAPGA
>A0A3P7NAJ6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thelazia callipaeda|TrEMBL
MFQVLLTLRDAIGRVDDETQQLLRDAVKVLSSSELYAPTITRFGNNDRIATGYYDGLIRL
HHLPRSRKRSVVDAFKDKRTTASEHRRVSADVIFERWKVNEALKCSMELISRWLSTIEAH
YHATNPYHNATHAADVLQATSYFLESPSVAHYVQEMHATAALIAAAVHDLDHPGRGNAFL
INTQQPLALLYNDQSVLENHHVALAFQLTLQSTNNINIFAGITREEFAALRQATVEMVLA
TDMSRHFEYLAKFQQAVSNLKENEENESNISLIVCRMLIKCADIGNPTRSWALCEKWAMR
IVEEYFDQTTEEREKGLPLTMALFDRNVCNVPLTQCGFIDMFARETFTSWSEFADIPILL
TQLEKNYEKWREQTSTWDPSRNTHLREERCHS
>A0A2P2CHA6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|metagenome|TrEMBL
MRQLGQYAAPRHAIAHLSDPHLIGGGRLHYGVIDNVAHLRAALDRLAAIRPVPQALVFTG
DLADQAEPEAYATLRSIVEPAAAAMGAVVVWTMGNHDERSPFARGLFDSDDDGFQDRVHE
VDGLRIVALDTSVPGYHHGTLEPEQLAWLADVLATPAEHGTLLAMHHPPLPLPMLRAAEL
IELHDQQALADVITGTDVRGILAGHLHLSTWSTFAGVPVSVASASCYTSDPAPVDRFVSG
VDAGQSFTMVHTYDDRLVHTLVPLERGTEVSHVGSDIAEALETVPLEQAFELASSKTSQF
NN
>A0A0W0U902|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Legionella feeleii|TrEMBL
MRIIHISDLHFGMHQDHIKEAFLAELALLKPAVIIISGDLTQRAKAYQFELLQSFLRCLP
GEVLVVPGNHDIPLYNLLGRIFYPFKGYKKYIAKHFNAQLSTDSLTILGINSVDPYQIKD
GQLSSKVIKKIKQYFRLEKKAVNILFFHHNFDHIEGLHKPLENEMEFLSFLRGSDIDIVC
TGHLHYAHVGLIRKDNMKPCVILHAGTLLCTRSKDGLNSYFVIDLEGDQCAIDWRVFAKG
QFLSRKNYSIKFSEVNAQLSS
>A0A0E4A5L6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodococcus erythropolis|TrEMBL
MTNINRRSFLTFAGLGAVGAVSLGKPWGLQYAGASTIPTSGPGTTLESVSTPVSSSGYTR
LTAGPGWANIVRSELAEPKSGREDRRTALASLVQLTDVHIVDAQSPMRFEYVHQITGSAF
RPQETLTAHGLISLVRRVNSIGSGPHTSRPFDAVVTTGDNTDNKEFAELDWFLTSLNGGT
VVANTGAKDRYEGVQNSGADLYWNPESPMLDMYKKAGFPEIPDFFGAAFTPVSSPGLNTP
WYCVFGNHDDSVSGTVPSGIPPLEAMYTGSLKFEVPGSPEQAKQIDIATKFDPSAIPGIL
SAFTTPPRQVTPDPSRAPFTPRQFIAAHLDPAHTGPGPVGHGFAPDAGETGIGYYSFQIA
PGVVGISMDSTNRAGLVDGSLGAAQFQWIENTLRAGSSTYYDAAGSRVTESRSDTYFVLF
SHHTSDTMDNLIPDPENVLEPRLRGSQLLDLLHRFPNVLAWVNGHTHENKITPWPGATPE
QGFWEINTASHIDYPQLGRIIEIADNHDGTVSLLATLFEAESPNSVEYSDKSAAGLASLY
RELSFNDIHRDPKLTGTGVDQNVELLVHTGR
>A0A1F2PV96|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodococcus erythropolis|TrEMBL
MRRTTIAIAAVTAALAVPGIAPAESQAEPSWGSSSFEWGSSSGENNTPPAAPGVSVPGGR
YEHPVDLTFTAERGATVRYTLDGTTPTTDSQAATPGRPLQIAQDTNVTVAAFRGDHASAA
VSFGYLIKTSEKPLAQVVVMSDVHVGDHANNDKKYESFFDTIGSIFPKPDAILSNGDMIN
DNGDGKGPDHKIVAEIFQANLARKGMNDTQLLISNGNHDASLAAIRAGYPAEWFPDSGGG
YYESDVSGVHLFTVNTETYNNDSAQRNWLKSRLTEITAESGNLTKPILVQGHRPASNTAM
DGQQASNPRLTEDLSAFPQAIFFSGHSHLNNNDDRSIHQRDFTSVNDGSMSYIEIDHGYQ
MVTESGLANRFESPTAQALFVEVYQDRTEINRINMAADKHDIYAGGAWSANWQPPYSSAG
TLSGSGWTVELDGSTNQQIKDNFRYTSGARNTHAPEFTSSTPLSVTTGENGATALRIAQA
KDDQMVHHYAVEVTDTATGAKVVSSKVLSDFYFMPRPNSLDIPIPDAAAGTAYEARVEAV
DAYGNRSPVTTLAFTR
>A0A1C3IUJ1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio splendidus|TrEMBL
MNTIYQISDCHLSDKSSYENLRRALEYVSKDTACHSIFLTGDICCNPKSGDYVRLEAFIR
QHISDQSIYAIAGNHDDSRLMRTEFKGSSIFVTDKATSCGREFVFLDSSFKPLDKRHPLG
SGRIDNRGMARLKQQLRKTNNPIVVIHHPVIPVGAEWMKAIRLENDADVMNVLRKYRVRD
VICGHGHDGITATQQGVTQYMAPSTAYGFDHSINEYNRSEKIGLSRISFSADSIDYQTVY
F
>A0A484SUL3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|plant metagenome|TrEMBL
MLIAQISDLHIRLPGQKAYRVVETDAYLPPVVDALNRLDPRPDCVVITGDLTDFGRPAEY
AHLRHLLAPLQLPFFLLPGNHDDRQALADAFPEHAYLRTDGPFVQYAVEQYPVRILALDT
VVPFKGHGALCAERLQWLETELAREPGRPTLIAMHHPPFKTGIAHMDAIGLLSGAPELAA
LVGRHPNIERIICGHLHRTIYARFGGTVASCCPGTAHQIALDLRPAGPSAFVMEPPGYQL
HTWQGGALTTHSAVLGEFPGPYPFHEEGALIDE
>A0A066Q1F6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli|TrEMBL
MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGFTLQELQGQPHNMVRHPD
MPKAAFADMWFTLKKGEPWSGIVKNRRKNGDHYWVRANAVPMVREGKISGYMSIRTRATD
EEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLPLRWRARGVMTLMFILLAAML
WFVAAPVVTYFLCVLVVLLASACFEWQIVRPIENVARQALKVATGERNSVEHLNRSDELG
LTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAKGTDELNEHTQQTVDNVQQTVATMN
QMAASVKQNSATASAADKLSITASNAAVQGGEAMTTVIKTMDDIADSTQRIGTITSLIND
IAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRSANAANDIRKLIDASADKVQS
GSQQVHAAGRTMEDIVAQVKNVTQLIAQISHSTLEQADGLSSLTRAVDELNLITQKNAEL
VEESAQVSAMVKHRASRLEDAVTVLH
>A0A1A6B1R4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium ragsdalei P11|TrEMBL
MIDNALKSILNFFKGIFKKKYRVIPQKINLKFNQNGEFKIVQFTDLHEYSLKNKKTIRLM
ENVLDTEQPDLVVLTGDIIDGRFCKLKEEVKKAIANIAKPMKDRKIPWAVVLGNHDNELC
MVNRKNQMKMYMSYKYNLSQSFSSAIGRAGDYNLIIKNSKNDKPIFNIYMFDSGSYDIKG
YGYIRKEQIDWYKKLSTNLKKEFGKIIPSLMFFHIPLQQQYKVWQSGKAIGERNEKESPQ
SVDSGLFSALIEMGDVKGVFVGHDHTNDYIGDLNGITLGYGRKTGYNSYGKKGFAKGARI
IILNENNLEKFKTYTKILSYINV
>A0A1A6AP83|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium ragsdalei P11|TrEMBL
MALFAISDLHLDLTGSKPMDIFGYNWANHDEKIKKNWNSKITSEDKVLISGDISWSMNME
GGACDLEWVHQLPGTKLMIKGNHDYWWNSITKLNNMYEDMGFIQNNFFTYKDYGICGTRG
WNCPESDNFSVHDEKIYKRELLRMKNSLNCAEEAGYKKFIVMIHYPPISEKFMSSGFTDM
FEEYGVEKVIYGHLHGESLSKAVTGKLNGVEYILASADYVKFNPIRII
>A0A3S4H216|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Morganella morganii|TrEMBL
MLHHHPLASGCTWLDQHSLRNSHMLAEVLTRYQNIEGILCGHIHQDLDVMWNGIRMLATP
STCVQFKPHCTNFTLDTAAPGWRYLELTTGDNPSLTTQLFRLDTDEFSPDLGSDGY
>A0A2G8Y765|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii COUG|TrEMBL
MKVSPHRTSERGSSPTGGEIGKHRFTQSGALRRQSAAPGGAKRSTMTGFLKAEPNPGSET
QDLEATQRRLKSAHRRTMLPTWILTGLSLAYVLFEGGRLLYETTLQQWSEEAILHIDKEI
FFLHDFAAGFYSLAEQLTSDYCFLNFMNAHSPPAAPTSTREEVQNLISGYAPSFCSWIKD
LYFFEEPLADTADRSTYQLLNTTYICGERFADLVQRINGNMVEVVQNYTLVKMRLIEMLA
PLVDNRNWSPHLLCDLDFSAGDLWACHDGLTALEQLRGQLSGYLGREWHLYSPILSIVIV
FILATLFFSRRHAFNAVFHTRFESLWAMLQQIDQ
>K0KQQ6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Wickerhamomyces ciferrii (strain ATCC 14091 / BCRC 22168 / CBS 111 / JCM 3599 / NBRC 0793 / NRRL Y-1031 F-60-10)|TrEMBL
MSFDITILGSSGGPLEGITCSYILKPSYISYKSIIEDNLSQYLIAIDAGSGLNRITEIIT
NEKSNSKESIANKILSYYEDSLSIQHYIHHSISINHHYNICTEINSSPIELSFKILNLIN
TYLISHPHLDHINGLIINSAAFHNQSNKSKLVYGLKETTEALQKYIFNDIIWPNLIHESN
GISFLDLIDIIPNESIQLNEIYKVIPFEINHGTKQYTNLEYKSTSFLIKDLNKNQYILIF
GDVESDKNSKFPKNKFIWESISDLITTGRLKSIIIECSTPNLPDQEPRFGHLTPDSLIDE
LKILQNIILNKSDTSPTPPLNGLNILITHVKENKFGKEPRKIILNELNELNEKYNLGCQF
SILLTGLTYTV
>A0A086M3M3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii RUB|TrEMBL
VVWNVVLDAFVVWAMSIDDSDPQNLGRVASKCGLQIIATAIIVSSFFCLVASMTRILSMD
ANIARHGTLWTSFVLVIIIDQLFSFLFSVLIWYAMLRRCGRQLPDESRFQYKIHPSPVLV
KLKKATRKIVNYNGFEMFFTMLLGWMVVDLTCRMILCQFFFDETAFLNQADRILEVVDFI
ILILFIVEICLRIAADGLKIYFSDPINCIDFFLVFFGFGIRIVDFFIQINKGIGNVLFIM
RLVRLYRLHRPPTGSLAIGKKEVFTSRVERIIAVLNKALEIEELTTREKDSLKWLIQTIS
SGKLYEMGSEEKKKTDSHVQAWISIISTQSQSANQMADDMENILLERVKQMTKAGDAETD
MPAVLQLEYGIDVSLDHAIEGYLANNLITWNFDVFRFHVIAGRAALPKLFVRCLQHQEVC
SLFNLKIENMLRFAMELEKTSFSTTPFHNSIRSAEVLQAMHLFLAFFDTQIKGFFNSREI
LAALLAAVVWDYQHPGFSSAFLIKTQHAIAIRYNDRNVLEHHHVAAAFSLMQKLGENDPL
LAFPEDQYIALRKIIIQLSQSGSRSNQTACLSLLKTKLQQAEFPRSITEDKNIILCNLMN
AANYSFLGRPLQLYLQWSQKYMEELFMQGDRELELDMPITKNCDRHTTSEAVVQLGLIDG
WAIPIYTTLAQTVPKLNAIVVSHLRRNRLHWLDEQQEEDKSKEKQTKVTPIKRYSKTKQG
STEATGNGELSKPEATTIEIADGTAGVPELRANANPLSEVD
>A0A8C5ICN2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gouania willdenowi|TrEMBL
MGLMLRRTEEKPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYPASVISVLKNVDKWSFDV
FALNESSGEHALKFIFYELLTRYDLISRFKIPISAVVSFVEALEVGYSKHKNPYHNLMHA
ADVTQTVHYLLLKTGMHWLTELEIFAMIFAAAVHDYEHTGTTNNFHIQTRSDTAILYNDR
SVLESHHVSAAYRLLQEDDEMNILYNLSKDDWRELRALVVEMVLATDMSCHFQQVKAMKN
FLQQPEGIDKPKALSLLLHTADISHPAKSWDLHHRWTTSLLEEFFRQGDKEAELGLPFSP
LCDRKSTMVAQSQIGFIDFIVVPTFTVLTDMMERIVTPLIDEASHSGLAGFRRSRHEVDL
LLKWRCVLNAHKQRHTTNATQRKYCIFPPHTGNDGSINTLIIKRHREQ
>A0A0K1EFD7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chondromyces crocatus|TrEMBL
MELRVIGCHGGETPKHRTCAFVVDDVLSIDAGSLTSGLDVGDQARLQACLVSHAHLDHIR
DLATIADNRCQMGCPPLVVAGTKGTLRTLQQHFFNNLVWPDFAAIPNREHPTIRYLELEP
EQPTLIAGHKVRAVGVTHTIEAAAFVIEGEDGGSIAYSGDTGPTDRLWEVLNAERDLRAL
LMEVSFPNREQGLATISGHHTPRTLGMDLRKYRAPQDLPTFLYHIKPVFQSEVERECAAL
RGLNMQVLQLLDHFVL
>A0A4V0BCA8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gordonia terrae|TrEMBL
MFVVAHISDLHFNGTRFNRARIQAALGYINARAAGIDVLLVTGDIADEGAASEYREAHGV
LESPLPMLITAGNHDVREPFSAALIGTETSGPINHARTVRGRDGSDVLFLMCDSSIPGRN
DGRLDDATIAWLSERLDATTADTPVFIAFHHPPVDLLMPFMDSIRQRDEGRLADLVGEHP
NIVAFLCGHAHTPAVTTFADRPLCVAPGVSSTLNLPFEGREVVNRGQPPGIAFHLYDEER
FVTHFRSVMF
>A0A1N6M6E4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio spartinae|TrEMBL
MLIAQLTDLHIKQSGKLAYQKVDTLGCLRRAIDHINHLNPMPDRVVITGDLADFGHPSEY
QLLVTELQRLKPLVRVVPGNHDNRTHLRDALQGWLAFDTPECCNFSEPLGGYQLIGLDTA
VPGQPYGMLSQASLQWLDEQLSAVTPHPALLFMHHPPMTVGLHHMDVQNLQNSDALYDVL
RSHPHVAGIVVGHVHRPIVATWHRIPVWIGPSHSHAVTLDLDPQAPACFSLEPRAIQLFR
LEPSGICSHISYIDAVDGPYPFFDDNHRLID
>A0A090S4U3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio maritimus|TrEMBL
MLIAQLTDLHIKKGGKRAYRRVDTLDCLRKAVSHINNLVPQPDYLVITGDLGDFGTPDEY
AVIKQELMKVEVPMLIVPGNHDHRANLREGLSELVRFDHPEFCNFVVEHDAQRLLGLDSS
VIGKPYGQLSSETLSWLEDTLGQHPDKPTLLFLHHPPMHVGLTHMDVQNLQNSEALYKVL
SKFNNVVGIVAGHLHRPITAVGKEYLYGSDLRIVIQ
>A0A086QBP5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii MAS|TrEMBL
MHRLLDWDFHVLALPPASAVLVTRDLLTQFALKANMDIPGEILMAFSVAIYKNYRPNPYH
NFYHALNVTQVLCLLLALPDVAAQFSPIDYLVLSVAALGHDLGHPGANNLFMTRFDCWPS
RIYQNVSVLENYHAASLFQILRHPAFNVFCSVSPTNFAPIRKRIISAILWTDMAKHFDVV
AKLQAKIQGEMVLAEGIIVTLTKPYLEGLLLHAADISNPMMDFELCRDWAFRACDEFYQQ
NKMEEMGGFPPSMPSFEHFDEYNVAKCQVGFIDAICKPLFNSLALMFPAQLGDRATQLQK
NRCVPLIIFPT
>A0A401M8X9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces sp. NL15-2K|TrEMBL
MLVLAHISDLHLDGTARATERAERVRDRLWRLPGRVDALLVTGDIADHGTEAEYEEAARV
LGLRDGDAPFPVLTCPGNHDSRATYRKALLGRPAADGPVNSAHVFDDGAVLMCDSSIPGH
DEGALDEETYDWIEATLDELDGALPAVLAFHHPPVALHHPLPDSYQLGRPDRLAALMQRR
PEIAGLITGHAHTPAATAFAGRPLVVGPGVTWTLRLPWEGEQVADREAPVGLAFHVLDDQ
GRLTSHFRVVT
>A0A1V4IXH6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium chromiireducens|TrEMBL
MRFIVFGDSKGKEKSGINEKVLKKIMNESSKIEPSPQFIVMCGDTVAGSNKEEILTSQLS
RFRNIVEKYHPNKLLLPIVGNHEVNIEPIDDKFEKVLSQIYNDLTPDSHLEGYNKTVYYK
DFEDTRLIILNAFHFGSTHKISEDQLSWFKEAASKCIKNKLVFIHSPAFPTGAHLGHCLD
LYPEYRDAFWRIVDECGIDIVFSGHEHNYSRRIVDNSFGNVDNCYKRKVTQVITGGGGEK
LRDKYKSKRGIVVAPIAVYHFLVVDIEVDYIKVCAISLNGKKLDEFVLDKTSGCGIT
>A0A447WH20|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella aerogenes|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFID
SSHAGTSKGWLTDETIGWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A0M2HCM5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium trichothecenolyticum|TrEMBL
MATATSVQFGQYPPARRTLLHVSDTHLLAGNAPLGGRFDTAANLARTLEAAEATGIRPDA
VVFTGDLTDLGEPEAYTALRAAVEPVAERLGAPVVWVAGNHDKRPALRRDLLGLAPTEEP
VTGVWDLGGLRLIGLDSTVPGWHHGDLDHGQLEWLRRELATPAPLGTILALHHPPLPSHV
PLFDILELRDQGRLADVIAGTDVRAILAGHLHYSTSGTFAGVPVSVAAATCYTMNLARPA
VEVNGMDAGQSFHLVHVYDDTITHAVVPVVEAPTGDVFSAEWVERMSRLTPEERLEAFSR
KRG
>M7AR23|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chelonia mydas|TrEMBL
MRGEGWSVGGGACEILDTEDELQEIKSDAVPSEVRDWLASTFTQQTRAKGRRSEEKPKFR
SIVHAVQAGIFVERMFRRTYTAVGPNYSTSVINCLKSSRLPALGGLSPAPNLSHGSSGPR
SDCAILYNDRSVLENHHISAVFRMMQEDEMNIFINLAKDEFVELRSLVIEMVLATDMSCH
FQQVKSMKTSLQQLERIDKSKALSLLLHAADISHPTKQWSVHSRWTKALMEEFFRQGDKE
AELGLPFSPLCDRKSTLVAQSQIGFIDFIVEPTFSVLTDVAEKFVLPLVEEGSKSKSSSS
QQSSSQWRQPSLDEHSELGDINADITSFRSTWTKYIQENKQKWKERAASGITNQTSIDEL
SPCEEEPHAPENQHNQNGDME
>A0A0M3IFM4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ascaris lumbricoides|TrEMBL
MIRTASCNRGLLKAFEIPSGALITYPSGALITYLLHLEHHYRDNPYHNQIHGGDVAQSTN
VLISCPSLTGVFSELEVLSAIFASAVHDVDHPGFTNQYLINSNSELAIMYNDESVLEQHH
LAVAFKLLQDSNCDFLVGLTKKQRQMFRKISIEMVNFFFFCN
>A0A1J5PA36|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|mine drainage metagenome|TrEMBL
MKLIHITDPHLVAPGRSLYGIDPEARLRAAVQHVCARHADAEACVLTGDLTHWGEDSAYA
RLRDCLRPLPMPVLPLIGNHDDRTRFRAAFPEVPVDAGGFVQWTHDTSGGRLFLLDTVLR
GDETGRTSAGYFGGGRIDWLRARLDAAQADGVAVYLFMHHPPFSVGIKAFDDINLIARDA
LDVGALLRQYRNIRHLFFGHVHRPIFGSWQGIPFSTLPATAHQSALDFDADKDLFSHEAP
GYGVALISPEQVTVHICDFLYAGPLFDPASERQGG
>A0A482ZZE2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured SUP05 cluster bacterium|TrEMBL
MRRLLQISDCHIDDIEQSIGVNSHQNLSLVVDKITQLESDALLISGDLSHHGSLNSYKKL
KQLLTPINTDLFVIGGNHDNEKNLSSVFGEYLFTLFTLGEWDIISVDSVQAGQTSGYLTK
EALLDLDTRLTQSTAKYILLVLHHPIVPMQSTWDDALSLENPQDLFTVLSKHPKIQAVLF
GHAHQSAEFIKNGLKIIACPSTAVQFTEEKRIGFNCYRLYDDGRFEYHTEWIIF
>A0A150HZ18|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acinetobacter venetianus|TrEMBL
MTFQVSTLSQKDFVMVQITDTHLLEYPHLEFVGMQPEQSFRAVIDLMRQQHSEIDLIVHT
GDLAQNPTPVTYHRYLEHMNTLGIPFFHTPGNHDDVAYFPFHETEPSKPTIVEVGNWRII
LLNSAQPERIDGKIADIQLQQLTQLLTELKDCYVIIACHHHPFAMQSAWIDQHKLKNSSD
LLETIEPFNNVKAIVCGHVHQDSINTWQGVEFLSTPSTCIQFKPKSDKFALDEEHPGYRY
IRLKSNGEIETQVYRLSNSQRMSSSEVLGYD
>A0A1E7WHB2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Duganella phyllosphaerae|TrEMBL
MNPKFPAKLWSASLLAALLAACGSDSSDNINNISDSKPATPPVAADPALPSVAFMSDVHF
ENVYGDLKSTRFAGIPTKDGRNATIRTMYAELTSTRLFNENYFAFRAALDDAYARNVRLV
GLPGDISDDAQPINIDGITDILKEYQAKGMRFFIAPGNHDPNEPYDDDEAGKNDFLTKDG
KEQKVYATGAAACKAGDSTVVCTNAMVEQGYEKLLAKLGDFGYMPNKGDVHWETPFTAYA
DGKYTYEAAQAASDVVRRQFEICTEGEGGKYKVAGKTYTNCTSIVDASYLVEPVKGLWLL
SLDVNVHVPNAKFDPANPKSFKGFDNAGDAGWNKMLTHKIHQMEWITSVMARAKAQGKQV
ISFSHYPTMDFYANQTDAMKAVFKPGAFQVTRMPAAATTGAVASTGLRLHMGGHMHFNGT
NDYQDSTGNYLVNVQSPSLAVFGAAYKIVTVLDQDKVDVQTVGLDVVKGYNELFPYYQVE
YDYLQGSTATADVAKRWNRSILDSKSYGEFTRTYFGELSRLRFMNDYWPCEMKEAAMALD
ARQMLILSQLQTKVTLAQLKDNAGVLPLTASCAAKGTPSGTVVAASQLTADWADATARAD
KLATAAGLKLDDFAKISAYEFYGDFHRTVYAGELALRDMGAQRVAQYKVLMGAFPASPAA
IVKIGDLPSDQNPVNVLFQNQFKQVFAILKGLGSAKPSDRFTIDFKAKTLTNANAGGLSF
N
>A0A166CBF1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Methanobrevibacter curvatus|TrEMBL
MKVLQISDIHSEINPRLNSYLDENKIDLLIISGDITNFGPSEFAMDYLNELKEKNIDIIT
IPGNCDTPEAISAIDSSETLSVHNNVVKYKNIIFFAFGGSNPTPFNTPFEFDEDTIYNKI
KSLIEKKSIDIADKSFNESIDDVKEDYFKVLLTHAPPFGSGADLIPSGAHVGSTAIEKII
KENNFDINLCGHIHEACSISKINNTIIANPGNLHESHGILFELKKNKLLNIEIVDL
>A0A378Q6E3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moraxella osloensis|TrEMBL
MTLLPSSISQHHADYFSIIELSDLHLFDDPNKLMNGVNTADTFASVLSLVRQQRDNVDLL
VLTGDLCHEPTPQNYDRLFATLNDVDIPFIAIPGNHDVTLELDSHLPFTQRRHLPVKADT
RLQNCYSIDTDYWDLLLLDSSCEGHSHGKIDEQSLRWLAQQLANANRPCVIFCHHPMVLI
DSAWLDEYTLINADRFWEVVMPYLDRIKAIFVGHIHQEMHKINYGISVFGCPSTSIQFKP
LCKDYTIDEIAPGLRWINLYNNGLLATGIKRTDTI
>C2FH64|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lacticaseibacillus paracasei subsp. paracasei ATCC 25302 = DSM 5622 = JCM 8130|TrEMBL
MKAVKYVAALFLMLIFAIVLGQIHPDRDRPLTNSSQATIWVLSDTHFIAPSLHDEKTAYT
QIKRSAAGKDMDYQPVAINALVQNALKARPTALVITGDVTFNGEKASAESIMRRLQPLVA
NGTKVLIIPGNHDIYDGWARANKGKRQLLTEQISPSDWRNIFHTSYEQAVAQDPNSLSYR
VNLNRNYQLLMLDSNIYTIEPSNRPPNTGGKLTPQTMKWVRQQLAAGQKAHRKSIVFMHH
NLYAHNEAVNQGFVLDNSDQLKTLLKAYHVPLLFSGHIHAQDISRDPDGQCPTIEVVSGA
FSISPASYGVVTFTPNRITYQKHATDPTPYLTAKQRKNPDLLHYQRYLKQLFLQDGEGLA
YGDLMDNGVTNQHDLDAAAKLMGVLNWRFFTGDDHPDKAELKRLKADPGWAVLERSPMLR
RYLKEIVQDHNMNDNHLIINHP
>A0A161M7C6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Triatoma infestans|TrEMBL
IRPVGCLHPQDTTPPTPPHTPQPSGCHSRCLVSKLFDVCSRSTLQEMECKEEIRIPWGTG
IVGFVAETGEPVNIPDAYKDERFNQDVDARTGYKTRSLLCMPIKDLNGDVIGVAQVINKQ
GDTHFTSNDEKIFSSYLQFCGIGLRNAQLYEKSQLEVKRNQVLLDLARMIFEEQSTTE
>A0A7U7HHG0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chryseobacterium sp. JV274|TrEMBL
MVSSVSIMKKTAVSLLALLLNIICHAQNFDVIPLGIYGGEQEDNLSAYLVGAPKNNAFLC
LDAGTVNAGIRKAIQLKSLDGSAETVLKDQIKGYFVSHGHLDHLSGLIINSPADSKKDIF
AIAPVIQILQNHYFITDTWINFADQGQKPILGKYHYNELQEGTEIPAPKTPFFITGYELS
HVNPYKSSAALVRKDDHYLLYLGDTGADRIEKSDRLDLLWNTIAPLVKKRQLNTILIEVS
FPNSQPEHLLFGHLTPNLLIEELSKLKEKTGQSSLESLSIVITHRKPTGDNPELIKKELL
KNNPLKVNYIFPEQGKKISLP
>A0A3G7Y761|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. R5-89-07|TrEMBL
MPSVSTVNPDVALLVQLSDSHLFAEADGMLLGMNTRESLQRVIERVHEQQPHIDLVLATG
DLSQDGTLASYQQFRDMTAPLGAPARWIPGNHDEPQIMAQAAVHSDLLEPVVDIGNWRIT
LLDSAVPGSVPGYLQDQQLQLLAQALSEAPNRHHLVCFHHHPVSIGCAWMEPIGLRNPEA
LFAVLDRFPQVKALLWGHVHQEIDREREGVRLLAAPSTCIQFAPGSEDFQVSEQAPGYRW
LRLHADGRLETGVERVKDFAFTVDYGSNGY
>A0A6P2FBJ8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Variovorax sp. PBL-E5|TrEMBL
MTTFLAQLTDLHIREPGRLAYGRIDTAPYLQRAVQCVLRLKQRPDAVVITGDLTDFGAAA
EYAHLQELLAPLPMPVYLMPGNHDDRDALRAGFPAHTYLGQGGFIQYAVRIGDLRLIAID
TCVAGHSHGALCAQRLGWLAEQLALYRDEPVIVAMHHPPFETLIGHMDQIGLLEGAEALE
ALIAQHPNVERVICGHLHRAIDVRFGGSIASTAPGPAHQVCLDLAPDAPAAWMLEPPGFR
IHAWRAGGRLVTHLAPSGSFEGPYPFNDDDAPID
>A0A1H6FE72|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thiotrichales bacterium HS_08|TrEMBL
MTKLSRRFFLQTIGAAVASTVVGCTSKPILPVQGSAKRHIRLAFYTDIHARKEWDTPEAL
AMAAASINAQHPDIVLGGGDYITDGFQSSVATVAHRWDAYMKMHNNIQATLFPAIGNHDL
VAALPEDGTPAAEDPRAIYLQKMGLARTYYAFDTLGYHFIVLDSVEVTGGKYKYRGFISP
AQMEWLKQDLAALKSDTPIVVITHVPLVTAFYNVTQGVEFKPRPNRVIVNNKEVLELFSQ
HNLILVLQGHLHVKERYQWGNTTFITGGAVCGKWWRRGNWYKTKPGYNLITLNDNHVEWE
YVEYGWQPRRP
>A0A0B1SEZ1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oesophagostomum dentatum|TrEMBL
MVNKHEGVFTKADEDSFEVFAVYCGLALHHAKLYDKIRRSEQKYRVALEVLAYHSVCNKD
EVAKLQKMEIKDRVEELETFEFNYLRMSELEKPLYAISMFKTLFQDQFRYDRDDLIRFVL
TVRKNYRRVAYHNWAHGWSVAHAMFVLLMHTSRDIFNTHEALALYVSCLCHDLDHRGKNN
AYMKTMMTPLASIYTTSVMEHHHFNQTVTILQQVG
>A0A1R4JFS4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Psychrobacter sp. JB385|TrEMBL
MPTYPAHKISTADKQVNILQITDLHLSTPLTSTADGDNKAAVCQDCFETVLHQALSTEIR
CDLIIVTGDLVSHVKTTIYDHIFETLHATGIPFACIAGNHDVTDEAGSDLPFLQRQLIPQ
PADTRLLTRHVIDTDYWQLLLLDSSITGKVAGEVTPADIDWLCKRLESCDKPALIALHHH
VIPVDSAWIDGHMTENAEDFWQHMAAYDHLKVIISGHTHQDQIRQRQGVTVYSTPSTCYQ
FKPFENDFAYDKNTQPGYRWLQLANNGEVASWVERLDT
>A0A3S4DMP9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Devosia equisanguinis|TrEMBL
MSDAVTFIHLTDLHVGNPDVPDAYLFSDTSSTLRRILAEIKTLVPQPKFIVVSGDLTNQG
DDGSYNHLKAIMAESGLDMPVLYALGNHDKRDGFYPAMLGRTEDLFAPYDHSAVIAGIHV
VVLDTSVPGKVGGSFEAGQLEWLKGELDSHAELPKLLVMHHAPALDTHNPDMEWEGLSFA
DTEALRHAVSGKNVIGILSGHIHYDRVANWYGIPSVVGIGQHAATDVLWLHEGLRMLDGA
AFAIGTLRPSGLAITFAPQAATRRELHSFTFARMTELLKQRDAAAVAAE
>A0A485M625|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|anaerobic digester metagenome|TrEMBL
MDARETKKNISGPGCGGGRTGVNGENAEDCFFAGQPEEKQSRGVPGLYDALTGWKTVIAN
EEFCTAGSDHAVVTWVTPGQKTDTSIYVGNTPANMVRYTFGQESEYHYAEIPGLKPSTRY
WYQVESNGARGSLNSFSTLPRPEGRRLFSFAIFSDLHITYGDPYGDINEIFFGKLNEFSD
ELMIQSILDSKKRDIDLAVLTGDLTDSASRLQYQVLKEQLLPRFGRTPYLLCPGNHDKFT
KNGGLGEMGFLKYAANGDRTYEYAVFKDCLFLLLDSCRQDDNWGYVDPGQIRWLQNILQD
NRGMPAFLFLHHPCNGPDLWFGVKNYRELQQAIRPFPGIQGIFYGHMHRCKVTANNFLTG
SRPYVTVPATVQFPCAYAIVTVYEGGFEYNTYKVKRLDLSEKSREKIVLKNMGKAAYTWY
SYGSIGDRSLSYSSGRLYSLHQFELSHTTNRARSLELYNRTQPFAGSSIALSRDGDLTRV
VLGRYGSFFQAARAYGEVLSRYGVRAAISSDGGVDEPWR
>A0A239SEE2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pandoraea sputorum|TrEMBL
MLFAQISDLHIKRPGKLAYRRVDTATYLERCVARLNTLTPRPDFVVLTGDLVDFGAREEY
EHLRRLLTPLEIPYYLVIGNHDGRDALREVFPEHTYLGKPGDFVQYTAMFGPLRLVALDT
QDPPNGGGKLCDERLQWLEATLASDTQTPTVVAMHHPPFACGIEHMDVQSLDASDAAKLA
AVVRRFDNVERVICGHVHRPIHTRFAGTVASVCPSPAHQVALDLREGGPSAWVLDPPSFQ
LHRFTPQTGLVSHLAFVDDAGGAHPFYDAAGKLID
>A0A8J4WJJ1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Paragonimus heterotremus|TrEMBL
MGSCTSTGVSRAESPIRSLSTSRSHDCFGQPRRMSPTRRLSSLTPKGFDQKHIQFNQQTG
SANQFENSVDLLELGVGNDDIPLRTVGPLITDAHLDNECTNLGVSPNFYKNLATCSLGEY
ARVPTDTDYFHAAHTPEAMRAAYTRMRQLYEAIEQDRVGKATLLKNLHYSITVMEASYIA
ERRRIREEEEDLSEAATEYVPNEVRDWLASTFTRTQPIVGIGDQKPRFRSVANAIRAGIF
VERIYRRMSSCTNLIIPPNVLMFLKTELDTWSFDVFALNEASENHSLKFVGYELFHKYNL
INKFQINTNNLECLFIQLEVGYSKYSNPYHNLIHAADVMQTCHMILHMNDLRYLTILNGR
FYSELALIYNDRGVLENHHVSAIFRLIQDPEFDIFTGLNKDQFKEFRQLVIDMVLCTDMS
LHFQQIKNMKSMITMPENVDKTKALSLIVHCADIGHPAKKWSLHEQWTKVLCEEFFRQAC
YHGYGVTFRSQRMLVGFIDFIVEPCFQVLGDMIERIISPPAVLPGSTPDLERKQNGSEKN
LQVEPPAVSRPWVECFKENKQTWATLATESKPKT
>A0A8D1EAI2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sus scrofa|TrEMBL
MESPTKEIEEFESNSLKYLQPEQIEKIWLRLRGLRKYKKTSQRLRSLVKQLERGEASVVD
LKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRR
SEEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIEALKDVDKWSFDVFSLNEAS
GDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTV
HYLLYKTGVAVSTDKNAEIALKMGWSDPAILYNDRSVLENHHLSAAYRLLQEDEEMNILI
NLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPEAIEKPKALSLMLHTADISH
PAKAWELHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKSTMVAQSQVGFIDFIVEPTF
TVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNNISSSDAKRSTVKSSGSEGSAPINNSVI
PVDYKSFKATWTEVVHINRERWRAKVPKEEKAKKEAEEKARLAAEEKQKEMEAKSQAEDG
AAGKAEKKASGEAKTHPVNGTRTNKSDNPRGKNPKAEKSAGEKQQNGDLKEGKNKTDKKD
QSSVGNDSKKADGKSITRIIFFRKVCSLMQAC
>Q1R6Q8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli (strain UTI89 / UPEC)|TrEMBL
MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGYTLQELQGQPHNMVRHPD
MPKAAFADMWFTLKKGEPWSGIVKNRRKNGDHYWVRANAVPMVREGKISGYMSIRTRATD
EEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLPLRWRARGVMTLMFILLAVML
WFVAAPVVTYILCALVVLLASACFEWQIVRPIENVARQALKVATGERNSVEHLNRSDELG
LTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAKGTDELNEHTQQTVDNVQQTVATMN
QMAASVKQNSATASAADKLSITASNAAVQGGEAMTTVIKTMDDIADSTQRIGTITSLIND
IAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRSANAANDIRKLIDASADKVQS
GSQQVHAAGRTMEDIVAQVKNVTQLIAQISHSTLEQADGLSSLTRAVDELNLITQKNAEL
VEESAQVSAMVKHRASRLEDAVTVLH
>A0A0F0CEQ4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium sp. FS41|TrEMBL
MYILHLSDIHYRREFGKGFRNANGDGYQNMLSAMQNPTVFLDECLDRVAGDRETVDLVVV
TGDLTEDGNAEDYRSLKHHIRERIGDVPLVVTLGNHDNKQSFREGWLKEGTDGERTAGSC
DSRPYHRVEWVDGTAVISFDTSAQGVPDGRLDEERLNWLRTALKEVGNHPAILVTHHHLL
CEQGQIPPLPESGRLLELIGDSGIFLILCGHTHHHYAGLAAGRPCHIADSLSFCGDNVGG
GKVRFQEKYGYNSYRIEEGMVRMSRSETFANGRILGTLTF
>A0A1S1HFI3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sphingomonas haloaromaticamans|TrEMBL
MLALDGVGKAGVKSAAGEERGKGAAQPMLIAQITDMHLGFDPDNPAEFNRKRLDRVIHLL
AHMDRRPDLVLATGDLVDRGDVASYRRLREALEALPVPAWPCLGNHDDRVNFRAVFPEIP
VADGFVQYAIDAGPLRLLVLDTLEEGRHGGAFCETRARWLADRVAEAPDRPTMIVLHHPP
IDTGIAWMTTDPEEAWIGRLDAALAGHRNIVAMVGGHIHRPMVAGWRGRPMIVCPSTAPQ
VALTLAPMDPALPDDRPMIVAGAPGFALHQWTGETLVTHFDAAEDHAVLARFDERMQPLV
TALIGERGAG
>A0A5P9B9T2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio sp. THAF190c|TrEMBL
MNIVYQISDCHLSDESSYENLRLALEYANSDASCNTIFLTGDICCNPKSGDYTALETFIK
QHVSNKSIYAIAGNHDDSSLMRAELKGSTICVTDKATVCGRELVFLDSSYKPLDKQHPLG
SGRIDNRGMAQLKKHLRKSNDPIVVIHHPVIPVGSDWMKAIRLENDTEVMKALQKYRVRD
VICGHGHDGITTTQSGVTQYMAPATAYGFDHSLDEYNRSEKIGLSKISLSANSIDCQAIY
L
>A0A1V5PEN7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|bacterium ADurb.Bin363|TrEMBL
MTNSWKVLFIIAIILSVFLCRSLAIENVKFVVFSDPHLSLPAEGVIDDFKLGLHSLELLE
NTIKDINEIPNLKFVLIPGDITKDGEPWNVDKFVEILSKLKVPFYVILGNHDQSIITQPG
KVCQAGLSKSTIIWALQGHGFNGPHGCWSTDPVPNLHLVGLDTNIIGYWGGRISEAQLKW
LDSDLSINRNKLTIVMGHHSIVPFSKDEEKDEWASFYLENGDKLLQLFVKYPEVAFYFSG
HRHISTRYIEHNGVYHIVHPSIVTYPMRYTVYELSKHYLDYEVRDVPVSSELWEMGKENF
LQFGDFWRLKDTPNTPEGNKKYLEYYESNDTKKARLPLRFE
>U6F9J2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactobacillus helveticus CIRM-BIA 104|TrEMBL
MKGKLFRKCKKTSQGKDLYYQETALTAFMRMAQRKKPAAIIVTGDITFNGERVSAEKFAE
IFKPLKHTQVLVLPGNHDIFDGWAREFRGKKQFYAGEISPMFWRSIFAKSYRQAFNTDDS
SLAYSVQLNPQYFLILADSNIYGTEETTAAPHTRGMIGKSQLKWIEKQLQYAEKINFVRF
YLCIIICMLIILL
>A0A1V6FUW2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lentisphaerae bacterium ADurb.Bin082|TrEMBL
MISSLRKLCICILAALPCLLTAATFNGRIFLDQNRNGRLDPGENGLAGVVVSDGHSVVLS
AADGRYSLDSAEAKPMLWYCRPTDHEPVGDFWRWGDTSQDNDFGLAHSPQNRDFTFMQLS
DSHLASPDRMQEFVKHLKALPFSLAFAVNTGDLVSSSDAGDINRAIAQFDAYQAGIANFP
YPLFQVIGNHDHPSISYDKRDLNHEFYGKGLYRHRFGPIYYTFDWAGVRFYALDGTEQHK
GLGYREALGEEQLAWLEKDLALLKPGTPIILLCHQPQVGIPGASSGLRDQEKLKKLLKGH
NLQAAFCGHLHNNHEARINDAPIFVTGAFSGAWWGGPNSDGTPQGYRLISVKDGVFQRTS
YFNREGHNAIARVAPSAKQYASGKQTMTVSVLDFGKPVEMKASIRNHDVALTPVLSSREP
LWSLWTMDFDSTTWPDSLYTFEFKTMQDGKESKGVTRCLLINGNDDKDFQAEGEFVLHLS
YSRADADAELLFNDHVIATIAKGRPCGRNEKDSITLPLDKIRRLNVLTIRPAPGQKGRVG
VSHVALRHQRKDKQAVNITDPRFYGHSSLTVNAEKPEAAGKRYFSVRD
>A0A445N7A0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces netropsis|TrEMBL
MIIIAHLSDIHLDGGRRSAERTRAVMDYLERLPCDLDAVLVTGDIADHARAAEYEQARQL
LVSRHPVLVCPGNHDERTAFRQFLLGQPGSGAPVNQVLHTAGCVIALCDSSVPGKDEGFL
EDETLDWLDGVLGRAPVGLPALVGFHHPPVPLHTPFVDGIRQFGQERLAALVERRPQIAG
FVCGHAHTPAATTFAGRPLLVAPGVVSTLRLPWERHGDPEGPAAHVHLDQPPALAFHILA
EDGRLTTHYRTVVG
>A0A653W9H6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. 8Z|TrEMBL
MPSHAPLATDSSVLLVQLSDSHLFAEADGKLLGMDTYASLQRVIEQVQQEQPEIDLILAT
GDLSQDGSLESYEHFRRLTETFATQVRWLAGNHDEVPPMQAVCSGTALLEPVVDVGNWRV
ILLDSSIPGAVPGFLADSQLELLERALAEAPQRHHLICLHHHPVPIGCKWMEPIGLRNPA
ALFAIVDRYPQARAILWGHIHQEFDQQRGDLRLIASPSTCVQFAPGSEEFQVGSEAPGYR
WLRLHADGTLETGVSRVTGITFEIDYSVKGY
>A0A5B7V2J1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces sp. YIM 121038|TrEMBL
MLVLAQISDLHLDGGARATERAERVMERLRALPRPVDALLVTGDIADHGEEAEYKEAARL
LFTDAPWPVLTCPGNHDRRTPFRTALLGEPAASASEAPVNSAHRVGGAEVLLLDSSVPGH
DHGLLDGTTYAWLEDRLDALGGRTPVLLALHHHPAPVHHPRLDTAWPLREPHRLRALVER
RPEIAGLIVGHAHTPAATTFAGRPLVVGPGVVSTLRLPWEGEGLVDLDAPAGFALHVLDD
EGRLTSHFRVV
>A0A3S9LST4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli|TrEMBL
MLFADADSLRISPREARSLIEQAEKRQKDAQNADKKAADMLAEYERRKGILDTRLSELEK
NGGAALAVLDAQQARLLGQQTRNDRAISEARNKLSSVTESLKTARNALTRAEQQLTQQKN
TPDGKTIVSPEKFPGRSSTNHSIVVSGDPRFAGTIKITTSAVIDNRANLNYLLTHSGLDY
KRNILNDRNPVVTEDVEGDKKIYNAEVAEWDKLRQRLLDARNKITSAESAINSARNNVSA
RTNEQKHANDALNALLKEKENIRSQLADINQKIAEEKRKRDEINMVKDAIKLTSDFYRTI
YDEFGKQASELAKELASVSQGKQIKSVDDALNAFDKFRNNLNKKYNIQDRMAISKALEAI
NQVHMAENFKLFSKAFGFTGKVIDRYDVAVELQKAVKTDNWRPFFVKLESLAAGRAASAV
TAWAFSVMLGTPVGILGFAIIMAAVSALVNDKFIEQVNKLIGI
>A0A8C4EUQ5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Dicentrarchus labrax|TrEMBL
MIAIDEKPKFRSIVHAVQAGIFVERMFKRAYTAAMPDQPAVVVNCLRDVDRWSFDVFALN
SASSDHALQTLFFELITRYGLNSRFKIPISCLTEFMSALERGYCKYNNPYHSHVHAADVT
QTLHCLLLRSGLVHWLTELEVMASLFAAAIHDYEHTGTTNNFHIHTKSEFALIYNDRSVQ
ESHHLSAAFRLLQHDQMNIFINLTREEWMELRSLVIEMVLSTDMSSHLLQVKAMKACLQQ
QERIDKPKALSLLLHTADISHPSKPWALHSRWTKALMEEFFRQGDREAELGLPSSPLCDR
KSTLVAESQIGFIDFIVYPTFSLLTDMAEKIVIPLVEENPGPIALLTTLLFLNSNLWRES
SRGLQWSLAHITAELVSFRSTWTRHTEDNKLKWKESGSNGMSYNN
>A0A1Z5KC81|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Fistulifera solaris|TrEMBL
MARFARDILYKFGVLVKQLEEKLGPDTGDLGLRVGLHSGPVTAGVLRGEKSRFQLFGDTV
NTAARMESNGAPNRIHLSKETADLLMQAGKVKWVKPREELIHAKGKGELQTYWLEYSRSE
SRKGSVNSVTDSIRSSLQSDYDESKKILSEISFNPMSEKLQRLVKWNTELLSKSLQLILG
RRVGTQIQVDDDDKMRALEMASRTVARQGKLVFDEVVEIINLPPKAEISDSDPLQLGVES
VDLSPEVYSQLHDYVRTIAAMYPEDNPFHNFEHASHVCMSTIKLLARIVAPNDDNGAGNL
HDNTYGITSDPLTQFAAVFSALIHDVDHPGVPNMTLVSEGTSLAASYQNKSIAEQNSIDL
AWDLLMDPAYEDLRRALYVNETEFNRFRTLVVNLVMATDIMDKQMGAFRKARWNKVFGDD
DEKDIRGSISQKDINRKATIVLEHLIQASDVSHTMQHWHIFVKWNERLFQEMSLAYDEGR
AEKNPAENWYQGEIGFFDFYIIPLAKKLESCGVFGVSSDEYLQYAQNNRNEWERKGHEQV
QIYIENYRMKRETMTMATPPSVIPQEEEEEEES
>L7VDF8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mycobacterium liflandii (strain 128FXT)|TrEMBL
MHRLRAAEHPRPDYVLLHISDTHLVGGDDPLYGAVDADSRLAELLEQLKHSGVSPDAVIF
TGDLADTGEAAAYRKLRAVVEPFAAELDAELIWVMGNHDNRAALRTFLLDEAPSMAPLDR
VNMIDGLRIITLDTSVPGHHYGEVRDSQLRWLAEELKTPAPHGTILALHHPPIPSVLDLA
VTVELRDQARLGRVLEGSDVRAILAGHLHYSTNATFVGIPVSVASATCYTQDLTVEVGGT
RGRDAAQACNLVHVYPDTVVHSVIPIGTGKTVGTFVSPAQAKRQIAESGMFIEPSRRDSL
FSHPPMVLTPSVRPNPAD
>A0A3G7TZW5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas synxantha|TrEMBL
MPSVSNVNPDASVLLVQLSDSHLFAEAGAALLGMNTRASLQRVIELVREQQPRIDLVLAT
GDLSQDGTLESYRQFRDMTRPIDAPARWIPGNHDEPLVMAQAAVHSDLLEPVVDIGNWRI
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPNRHHLVCLHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQARALLWGHVHQEIDRERNGLRLLASPSTCIQFAPGSEDFQVSEQAPGYR
WLRLHADGRLETGVERLQGFEFTVDYGSNGY
>A0A1V5MCA3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|candidate division TA06 bacterium ADurb.Bin417|TrEMBL
MKRKWLGLAMAASMLLAGTAAGAATLVDSFEKGYQYDRDLHSQQGWQASRTGVAYEGLVT
LTDREAKTGKYSVWLRPKSPDGKNIGMSRTLDFQKEVGWIDFWLKCAYGPSSRILVSVSG
ENFSAVAGAQPGFVYGGDTVEYNRIPADRVPVKDKQYFKPNEWTRFTLRTDSRQGRFDLY
LNGRLALKDLQANKNGGPGNIKNLSIALRAYGTPEELARDQVFIDDLYLSDEMPPTNLVI
SADGSFAVAHASSSSAEAAVSVSVSPSGASAVSASGGGAVQPTISIDGKVVQSSSTNLVI
SDQPFFPVRPKEVLFRFVHISDSHARADGTSMMELNRVVNDINRMGVDFVLHSGDLADAG
NIKGTEMALAELKRLKMPFYLTPGNHEKFGEVGKAGRYEEMTGFKPYYSFEYKGFLFVAL
DTPVAEPDHMGALDEAQLTWLEKELQKGKPTVIFTHVPLYGTYPQGSQAYEIKGPSREKL
EALLAKYKPAAFLAGHLHRVNLFKETENTFFSVAPALTPLYNWAPGKGYVIWDVYPDKVA
QHYQYIYYPYVKEEGRTYGESKFKK
>M4UIZ2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ralstonia solanacearum FQY_4|TrEMBL
MRFIQSLLVLNEGDAALDRAMVEMTAARGNKTVTVVQITDPHLFADRDSELMGYRTYPML
SKTIDAIRGHDFRPDACFLTGDISQDESADSYELARFELERLGIPVFWIPGNHDDRGRAE
AVFGQSERIHRLSKLTTADWDFIHLETCRRGADEGYLSDPDFERFVSDVEASAGEGKQIA
VVMHHHPVPTQTPLLDGYMLQDGERLLSFLDDQRQVRLVICGHVHGDYQLQYGSQTIEVC
PATCFQWEKGTRTAKAEDWRGFRIFEFSSAGYQSALISV
>A0A5C5W6C6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Phycisphaerae bacterium RAS1|TrEMBL
MKAPSLSRREFVHSASALAAVLALPGVARAHDEHEGKPAAATRKRALRIAHLTDMHVQPE
RKGDQGFTACLRHLRAQKDPADLILFGGDTVFDSFDENESRTRMLWELWQKLLKDECGTE
HACCIGNHDIWGWNKSKSGTSGSEARYGKRWVLEIFGVEKPWRSFDKGGWHFIILDSTQP
DGGDGYIAKLDDEQFEWLQGDLAATPATTPVLILSHIPILSAAAYMGNGAEKSGNWVVSG
SVMHRDARRLKNLCRKHANVKLACSGHLHLVDRVDYLGVSYLCNGAVSGGWWKGANQECE
PGYAMIDLFADGGFESQYVEYGWKAAADA
>A0A081R8T0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sphingobium chlorophenolicum|TrEMBL
MLIAQVTDIHLGFDPDNPAEFNRKRLDQVLRALNDGPNRPDLLLATGDLTDRGDADSYRR
LANAFSQCDFPVWPCMGNHDDRAQFAQYFPHIPQEDGFVHYVIPLEDRRIIMLDTLEPDR
HGGAFCERRAAWLSARLDEDSTTPTLIVMHHPPVEVGIDWMNTHPEEAWVQRFTATIAGR
PNIQAILCGHIHRAITAPWQGTTIAICSSTAPQLVLDMRPMDPDAPDNRPMIVADPPAYA
LHRWTDHGLITHFATADDHVMLAKFDAGMQSLVRTLIDERPA
>A0A3P8KRQ3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Raoultella terrigena|TrEMBL
MLLAQISDTHFRSHGQKLYGFIDVNAANADVVSQLNALQERPDAVVVSGDIVNCGRPEEY
EAARQILSGLNYPLYLIPGNHDDKALFLEYLQPLCPQLGSDPQNMRYAVDDFATRLLFID
SSRAGTSSGWLTDETIKWLEAQLFDGGDKPATVFMHHPPLPLGNAQMDPIACENGYRLLA
LVERFPSLTRIFCGHNHSLTLTQYRQAIISTVPGTVHQVPYFHEDTRPYYDMSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTQER
>A0A3P8IQW3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Raoultella terrigena|TrEMBL
MDQHSLRNAAALDRALAAFPRVRHLLCGHIHQELDLNWGGRRIMATPSTCVQFKPHCDNF
TLDTVSPGWRWLDLHPDGTLTTEVCRLSGVKFHPDIASEGY
>A0A2H6JZH2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|archaeon BMS3Bbin16|TrEMBL
MRLVHISDLHFGSRFNETVFESAVEEINSLEPDALVVSGDLSDEGLTHEFERARDMLKGF
KCKNLIVCPGNHDYRNTGYLILKDYFSLKQVYETEVAKIIVLKTARPDKNEGEVGYRQQL
WLEKQFRDTGKTRIVVMHHHLIPVPDTGVERDTVIDAGDVLAALKRSKIDLVLCGHKHRP
WKWDFEGLKIMHAGSLSDIRLRGFFHNSYNIIDVDEKGIHGTVKVIGGDELSFDVLEKER
MN
>A0A517PXA7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia chilikensis|TrEMBL
MSPIKPDSRISLGRRAFLQQGALVLGGLTAAPLGQLAAAADQKQRGAVRVGLVTDLHYAD
KPPGGSRHYRETLKKLDEAVTQFKKDEPDFVVFHGDLIDSGKSLEQEKQHLQTIVTAIDA
IPYPRHFVLGNHCVDQLTKAEFLKGVGQKESYFSFDRGGYHFVVLDSCFKSDGTPYGRHN
FKWTDANMPASELKWLKDDLQQTKLPTIVFVHQPLDLKDTDAHAVKNSSEVRKVLESAGN
VAAVFQGHSHRNKYSEIGGIHYCTMVAMVEGSGPTNNGYSTLDVYADGSLMLNGFRKQQD
YHWS
>A0A0F0L6B4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium oxydans|TrEMBL
MTAPVSTEYVFGRHQPASHVLIHVSDPHFLAGGARLGGRYDVESNFARTLEAIRQVHPHP
AAIVVTGDLTDLGEPDAYRRLRAALEPVAAELGTVVVWVAGNHDERPALREALLDLAPTE
EPVTGVWDLDGLRLIALDTSVPGWHHGDLDDAQLAWLRDVLAEPAPHGTLLAMHHPPLPS
HLPLFDILELRHQDELAEVIRGSDVRGILAGHLHYSAHGTFAGVPVSVSSATCYTMNVSL
PAAEVNGMDAAQAFQLVHVHPDTITHTVVPVTEAPTGEFFSEAWLERMAALTPEQRLEAF
SRKPAR
>A0A1B1NSY8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio scophthalmi|TrEMBL
MDMLKTKLAVLVGCLSLGIAINASAAGFETVTLGSKGGIQDGNLTAFMLKSELDDNYVLL
DAGSVVNGLIVSDQKGAFADVKVPEDSKYTKVGYLLKEKIKGYLISHAHLDHVAGMIISS
PDDSHKPIYGLASTNEGLMNNYFNWSAWPNFGNEGNGFKLSKYTYTDLTQYQWQAVKGTT
MQVMAMPLSHSGGESTAFLLKDTQGDVFAYFGDTGPDAVEKSDALNKVWSALTPFVKQGQ
LKGIVIEVSFTNETPDKALFGHLTPNWLMKELTALESMAGKGSLKDLDVVVSHIKYSLKK
GEDPQVVIKRQLDTANTLGVNFLFPAQGDALTF
>A0A1E3WPA4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio scophthalmi|TrEMBL
MKSSSKKARKFSIRFTVGSMFLFATVLTAIFAISLQYYFSRQMTEEHVLSKLTMASSEIS
DYIQQIDVNATSSAQILRTVSTAAEKQFSEKEIRDIFVQVLKDNPLFYSLYYGNSAEDFY
QIINLESSPIVRERIDAVEQDRWAIIKIRGVGHDRVRTTEYFDASLKRTRMLSQESNYFP
SQRPWYHSATNHGVFKTDPYLFKHLKITGQTYSIRSKNAVIGVDIVLSSLSSKIAEDAKG
IYGGDGVEAFLFNHNGEVIASNINQQAPDTLPISVPMTLTDQQIRDVQHAPILKVSNQNN
WGPYDFAQAGQPKGYSIDQLKIISQMTGLQFEFVNGFTTQALMNKFAQGELDIVHSLTSE
HPLNFSGNSAEMYTVALGVAMNNGKQLPSELSELQQGRVGVIEGRGIQQLIQKRSPQLTI
IPIADFEQAKARLLGGGIDYMIDSYFALNEMKGAADADKISVGHLNDLNQVAFNLYTNKP
NAHLLPLIEQAIKQISPKQKQRLRLKWLDEDVSKGVFVPYPELYNLSLDSSLHKQMISAQ
NGERFLYVTPVSTSGALEYFAVVVPSEVITAQVIDRLVTSISITIGIMLLLLPIAWVFGS
PIVQPISHLRRETLRIKQRQFSQVRLVDTRIKEVHELSLSMVDMASEIERHAKEREAFID
AFICLIAQAIDDKSPYTAGHCNRVPELGVMLAKIAEETDSGKFKDFRFNNEDERREFRIA
AWLHDCGKITTPEHVVDKGTKLEANYNRIHEIRTRFEVLWRDAEIEYLRSLLDQSSDKAS
AFEKLHNRQSELKQDFEFVAKANVGGEFMSDDKIERVKSIAKQTWLRHFDNRLGLSPFEE
LSKVPPQGSLPVKESLLADKPEHIIHRVRQIEFEEKHGIQMEVPTHQYNYGEVYNLTISR
GTLTPEDRFKINEHMISGIKMLEALPFPPELSNVPRFASTHHETMDGRGYPRKLTASELS
VPERILAIADIFEALTAADRPYKKAKPFSVAIDIMHKMALDKHIDKDLFLLFLTSGGFQQ
YAEQYLPPEQIDHVDIRKYINQPEPA
>A0A379TJT0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salmonella enterica subsp. arizonae|TrEMBL
MLIGEEWQILLLDSQVFGVPHGELSEFQLEWLERKLANAPERQTLLLLHHHPLPAGCSWL
DQHSLRNAAELDSLLAHFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFT
LDTIAPGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY
>A0A0F0KWP6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium foliorum|TrEMBL
MILTEHSRPSHTFVHISDTHLPGERSPLYGSGADADANLASVLDRLVSSGLRPDALLFTG
DLADRGDASSYRRLREMVEPAVEALGCEVVWAMGNHDERAAMRAELGLAGRPSDAVIEVR
WFGGMRVIVLDSTVPGEHWGRVDATQRAWLAAELSRPAPEGSLLLIHHPPLPTVLDLAVT
VELREQVALAEVLRGSDVRGILSGHVHHPSFGTFAGIPVAAASSSAYGQDLAQPVGATRG
QDAAQGYNLVHVYDGTIVHSVVGLEVGADVGEPVAADEAGRRIAHRGISWRSPAPAR
>A0A1M5ZND7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio aerogenes CECT 7868|TrEMBL
MENAMLIAQLTDLHIREGGQPAYRQVDTLACLRAAVNHINGLIPRPDLVVITGDLGDYGT
PEEYAVVLPELNRLLPPVQVIPGNHDHRGCLRESLATLTTFDHPHYCHFIRECGAYVLIG
LDTSVIGEPHGYLTEETLRWLDDVLKSNTDRPVLLFMHHPPLAVGLHHMDIQKLQNDDQL
HEVLLGYKHVKGIVTGHLHRPVFALWHDIPVWVGPSHSHAVTLDLDPRAPSSFSLEPEAI
QLLTLTPDSVVSHLSYIHASEGPFPFFDEHHQLIC
>A0A0M2H475|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium ketosireducens|TrEMBL
MRTAEYPAPDRILLHISDTHLRADGTRIFDVVDGAERLERAISAIEASGARPHAIVFTGD
LADHGEPGAYATLRTMVEPFAARLGARILWVMGNHDDRAAFRAGLYDDLSADMRPIDRVD
ELDGLRIVTLDSTVPGEHHGELRDEQLAWLADVLATPAPLGTVLAMHHPPVPAVLPLAAS
VELRDQSRLARVLRGTDVRTIIAGHLHYSTFATFAGIPVSVASSTCYAQDLTVPVGGTRP
QDGAQAFNLVHVYDDTVVHSIVPVEAPRVMEYIDPVEAQRRLRAAGIAPVSASRTDAPTE
PIALVR
>A0A7Y0IIF6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pedobacter sp. SG918|TrEMBL
MLKKIFSVLLLLSLCAIHSSGQRINTAFKIIPLGVKGGDDESNLSSYMIAPKGSEKYVCL
DAGTINAGIQRAIDHQSLKGISEEIQRKQIKGYLISHAHLDHVAGLIINSPADTAKNIYG
MPSVLNTLRDKYFTWDAWANFANEGEKPQLKKYTYFPLIEGNTYPLEGTEMKVKAFELSH
GNPFKSTAFLISHGESYVLYLGDTGADEIEKSDKLANLWQNIAPLINSGQLKAILMEVSF
PNEQPEKQLFGHLTPKLFYSELSKLQSLTNEKALKKISLIVTHIKPPQHNAEKIKQQLLL
GNILNLNLIFPEQGKLLTIN
>A0A7R6PUP4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thermotomaculum hydrothermale|TrEMBL
MKVEVLGCSGGKDKNSNLPSFLIDGKILFDCGSVCSSLSVERQGDIEVCFISHAHFDHIC
DLPFVADNLSISGKNLRIFATKETLKLISENVFNGKIWPDFRKIPDRENPTLIFEEVSDG
EVLKIEGYEIEFFNVYHTEGSIGFIISDEKSKLAYTADTYQTNGLWKKLYEKGVKSIITE
CSFPSKRGKIAEVSYHLSVETFIQELKKMDKFDNIFVFHLKPHYKDLIEKELKSFDVKIL
KDGEIIEI
>A0A1S1VBL9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Andreesenia angusta|TrEMBL
MNIYAMSDLHLDSTGEKSMDVFGEVWENYQEEIFKNIEDTVSEGDMLLVPGDISWALKPE
EAYLDLKKLDALPGKKLLGKGNHDYWWGTKAKLKGMELETIDFVQTNSFKIGDVGVFGTR
GWSSKEGEEYSEQDEKIFERELNRLEISLETLKDEKLSKRIVMLHYPPFRFSDSSPNEFV
DIMKRYGVDICIYGHLHAEGHKFAVEGSVEGIEFHLVSCDYLKLKPKFIAIGGE
>A0A1Y0N787|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Curvibacter sp. AEP1-3|TrEMBL
MDGSDPAIIEPTDADVLVLAGDIHDGYKGIERFQSWKPDTDVIYVAGNHEYYGHVYRSKQ
AQIKARANEVGIHFLERSAVVIKNVRFLGATLWTDYRLFEPRYSQPLAMHEAKQSLNDHR
LIRMEKGAFSPSDALANHAQSRQWLTDELARPFDGKTVVVTHHGPHPNSVHEKYQGDLLS
AAFVSDLGDLLQGADLWIHGHVHDSFDYQIDRCRVLANPAGYVLNRRSIKSMEEAKFENP
KFDRSLVLEI
>A0A094YVB3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acetobacter tropicalis|TrEMBL
MSFTKSIFCALLAAIAGHAFWAQPGRAEGNTSRAAPSQNGFDILVLGARGGVQDGNLSAY
MIMPYGDHHAIMCDAGTLVNGLNVSDHLGKLTDFSVENTTPLTPTGYMLHHVIQGYLISH
AHLDHIAGLAISAPDDTPKPLYALQSTVDDLSHSVFNWRIWPNFADQGSAPFLKTYTYHP
LIPAQPLPLQNTAMEVTAWPLSHGPVISTAFLIKSGSNALLYLGDTGPDSVENTHRLKTL
WHAVAPDVQNHQLKAIIIESSYDNSRPDKTLFGHMTPRWVLKSLHDLAQETGKATSLQGL
TVLISHIKYTLTTGKKIQDTIRRELDAENDLGVKFVIAEQGLRLHVQ
>D8IWM0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Herbaspirillum seropedicae (strain SmR1)|TrEMBL
MRRVIHLSDLHFGRTDPAIIEPLIAQIHELQPDLVVVSGDLTQRARSSQFRQARQFLDAL
PTPQLVVPGNHDVPLFNVAARLLQPLRKYKRHITPDLQPLYVDDEIAVVGINTARSLTIQ
DGRVNDRQIELARRELAAVGDHLVKIIVTHHPFDLPPGPQHHGLVGQALPAMRAFALCGA
DLLLAGHVHASSAVSSAARYRIAGYSALVVQAGTATSTRGRGEANSFNVLQIEAHQIVVH
RLGWRAEERAFGLDASQTFVQRGSEWFEQLADGQIATDP
>A0A4W4HN50|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Electrophorus electricus|TrEMBL
QRLKCMIRDIDESNVDYEQFKKNLEYTASLLEALYRDETRQSLDMEDQLQELRPDSVPKE
VHNWLASTFMQQARRPLRYPDYKPSFRSIVHAVQAGIFVERMFRKMSSTAMTDQPLAVVN
CLRVDRWNFDVFALDVGSSGHALKTLFTELMIRYELNSRFKVPISCLMSFLCELEQGYNK
HNNPYHCQTHAADVTQTLHCLLLRTGLVHWLTELEVLASLFAAAIHDNEHTGNTNSFHIL
TRSDLAITYNDRSVQESHHLSSTFCILQNEQMNIFTNLSREEWVELRSLVIEMVLATDMS
FHILQVKAMKHSLQQQERVDKAKALSFLLHTADISHPAKPWVLHSRWSKALTDELFRQGD
KEGELGLTISPLCDRNTAPVAQSQIGFIDFIVDPTFSLLMDMAEKIIIPLVQDNPEPPEP
INRHRYTEIVLSLLTGEAGAWGTALWDSQDPVLQSETGFYNLFKVVFNHPADENDPGTIS
CETHSVIDALAIPL
>Q4KL87|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Xenopus laevis|TrEMBL
MDSDMKQSSETPSNIPTSKSNQQITQPSEETRKALKQPTFNVWGMERKQMLCLLEQMFYE
LDLVTEFKMEPETVRCFLTSVQKHYQENPFHNFYHGFSVTQMMYCVISQCQLQEHLSHID
ILTLMVAALCHDLDHPGLSNSYQVNAQTDLARQYHNKSPLENHHWAVAWRILSQKQSNLL
LGADPKQVPHIQQEIMELILATDMAHHGEILQTLQNIENFNFSNREHVTALKKGLIKICD
ISNEARPAEQAEIWADALMEEYFLQSDREKDEGLPVTPYMDRDKVKKADAQSSFISFLLI
PLCEALCKHFPLLNNLLLQPLRAARLRYQQQMDNGMLERQDM
>A0A3P8BUA2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Heligmosomoides polygyrus|TrEMBL
MALELQCLLYRKVQEAQRRSHMAAELLVQGSQLLVRCFLFWSPQFDRFSFSPRSIGDGDA
YIAASMTMFEDLGFTARYSMNKRKLASFLLRVAKGYREVPYHNWSHAFSVAHFCWISLRT
PAVLHGLDELERLALLIACLCHDIDHRGTTNAFQLQSKTPLAQLYSSEGSVLERHHYAQT
VQILQMAECNILDQLTRTQYQTVLSHIRDVILATDIAVHLGKVGRIKAMVDQGYDPLSRD
HHYLFMCLLMTSSDLSDQSKDFRNSKAIAENIYREFFSQGDLEKQMGASPMEMMDRDRAA
VPKIQLDFMDTVALPVFEMVAKIVPEGRSTFEAITLNRQCWAALDEILVERGNRPVLGLD
YLRDQELEQQVVERELPAVSGVFGRLLRIELVHVRVLV
>A0A0M3K1V1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Anisakis simplex|TrEMBL
MNTFQLHHPTRQRKRSVVDAFKEKRTVSGDARRRVSADVKNALSNDRDWGFDILRLERVT
ENHALSQLGIKIFERWKVHDTLRCSSDLIAKWFTVIENHYHSLNPYHNATHAADVLQATS
YFLDSPAVAHHVQDTHATAALIAAAVHDLDHPGRGNAFLINTRQSLALLYNDQSVLENHH
VALAFQLTLQQSNNVNIFAKLHRDEFVAIRQAVVEMVLSTDMCRHFEYLTKFQQTIGNLH
ECDEERDTTSMTVCRMLIKCADIGNPTREWNLCKQWAMRIVEEYFDQTSEEREKGLPLTM
ELFDRNTCNVPLTQCGFIDMFARETFTSWSEFAELPELLKQLEINYENWRQQTTNWNPAQ
NTNLIDT
>A0A0R3QLL3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Brugia timori|TrEMBL
MLGNSYGFHNLAIRKHACRLRYVLHQLNGGQLSMDDLKKNLEYMALLLETECMNETRRIC
DEEDDLADVKPEAVSDEVRKWLAATFTKQSMLSKREKPKLKSVANAILTGIFFDKMFRKS
QVLLISTPPEIAALMKNLNSWSFDCFRLNEVSEGHALKYVGLELFNRYRFLDRYKIPVQI
LENYIGALEVGYSKHNNPYHNIVHAADVTASSHFMLSQTGFATSLSDLDILAVIFGAMIH
DYQHTGHTNNFHIQTG
>A0A060VJ30|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFID
SSHAGTSKGWLTDETISWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A1U3ISC5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mycobacteroides abscessus subsp. massiliense|TrEMBL
MTGEQDPSSMSRRQLIRHTAWFGAAVALTVAGGEVISHVAGSAAAAATTRPTLRFAQISD
SHLGFNGTANANVVDSFGHAINQINNLGYTPDFVIHTGDLTHLATDAQFDQAKQMMSGLS
TPHVFTVPGEHDSIDDAGQKYRSVFGDGTRGDGWYSFDIAGVHVIALVNTLNLKKLGHLG
NDQLEFIEKDLAPVSSDTPIIVFSHIPLFAMYPEWGWGTDDSAQALSYLKRFASVTCLNG
HVHQLFTKTEGNITFYSGTTTAYPLPKPGDGPAPKPVTLPAGQLHDILGIREVSYLRGTQ
PLALKEDKLT
>A0A2H6JXF8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|archaeon BMS3Bbin15|TrEMBL
MKIVHISDLHTAGPNFIPEWGQKVIEIVNSIRADVLVVTGDLTDDGYAHEYDIAKKYLDR
IKAKSTVIVPGNHDARNEGYMIFEEVFGTRFPYYEDESVVILGIDSTEPDIDDGHIGREN
YAFMREKLSVDNRIKILTMHHHLIPIPGTGRERNIPVDSGDVLKLCNELGLNFVFSGHKH
VSWVWRLENTYYITAGTATSQRLKGRSYPSFNIVDIEDKKLSIKEVNVMDETMKEILKIK
LTPQ
>A0A158QN00|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Haemonchus placei|TrEMBL
LCDTVVTTVDGQKFDTRDLDNDRGMAMVADWSLPIFEIAEKYSKTVLSRLTYTVFKQADL
FRIFKLSPIKFFNFFHALERGYWDIPYHNRVHAADVLHGCYYLTCHPVRPLIGPTTSPDS
LLPPPPPMAAPISASMSTLELMALYTAAAMHDYDHPGRTNAFLVAAEDKKAILYNDRSVL
ENHHAAESWRLLQLAENNFIETLDPAETKRFRYLVLEYILATDLKQHFEIIMTFNEKSSE
MELQNESDRLLMAKMVIKMADINSPTKPYSLHRQWTDRICEEFYEQGDEERRRGMPITPY
MDREDAQVAKLQDSFIAHVVSPLALAMNEAGLLPILPGLVEPEMIINLKHNHQKWLQEID
STAAEQVSTMGNGVIEEESSTSDSPDNRKCSPSLDSEVEVRQLTYLISFALKW
>S7V380|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii (strain ATCC 50853 / GT1)|TrEMBL
MWFYSYLRHPNDVPSLCTHIRSSNIFLRLGPQYYLPEDERKSLFVRTCHLLYYLASLLFL
TTLTTYTAIKIPSSPSTTTELLSQLFPFNSIDDCNERLSCKVDCVLYAFPDLNCAKDDGS
LLTFGGNSYSSLYFYHYPGKDVPLQKEARTAWERCYQIMRETTGRLQFLQQDRETVERTH
TCFAGCKTNGAVTFTQKLTDGTPVVFDSGTDWLQMAPAGSLPQDTRPACNPSEPPSLLCV
EPTDECQHVTLRYQVCIGDTAFCFDIVRILITIALGVVWNVVLDAFVVWAMSIDDSDPQN
LGRVASKCGLQIIATAIIVSSFFCLVASMTRILSMDANIARHGTLWTSFVLVIIIDQLFS
FLFSVLIWYAMLRRCGRQLPDESRFQYKIHPSPVLVKLKKATRKIVNYNGFEMFFTMLLG
WMVVDLTCRMILCQFFFDETAFLNQADRILEVVDFIILILFIVEICLRIAADGLKIYFSD
PINCIDFFLVFFGFGIRIVDFFIQINKGIGNVLFIMRLVRLYRLHRPPTGSLAIGKKEVF
TSRVERIIAVLNKALEIEELTTREKDSLKWLIQTISSGKLYEMGSEEKKKTDSHVQAWIS
IISTQSQSANQMADDMENILLERVKQMTKAGDAETDMPAVLQLEYGIDVSLDHAIEGYLA
NNLITWNFDVFRFHVIAGRAALPKLFVRCLQHQEVCSLFNLKIENMLRFAMELEKTSFST
TPFHNSIRSAEVLQAMHLFLAFFDTQIKGFFNSREILAALLAAVVWDYQHPGFSSAFLIK
TQHAIAIRYNDRNVLEHHHVAAAFSLMQKLGENDPLLAFPEDQYIALRKIIIQLSQSGSR
SNQTACLSLLKTKLQQAEFPRSITEDKNIILCNLMNAANYSFLGRPLQLYLQWSQKYMEE
LFMQGDRELELDMPITKNCDRHTTSEAVVQLGLIDGWAIPIYTTLAQTVPKLNAIVVSHL
RRNRLHWLDEQQEEDKSKEKQTKVTPIKRYSKTKQGSTEATGNGELSKPEATTIEIADGT
AGVPELRANANPLSEVD
>A0A3M7Q0U2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Brachionus muelleri|TrEMBL
MSNLHAKLLYVRIENRIECIEFDSNTTTEDLKETLRSAAEANQNDILKLYNHKGNLVAIN
GSLPVNISSEPYRLQVIAKNIVDYNNELKDLIERIEHLEIQLNSLSSQRVEDLHSKVKNL
CSKLENIDHLSFIGLFKDTRLYTVGTFSNEKNETKKENIQNVYEKFKSFSMVKVDDETRQ
FLKSPHFDNWKFEDAELLVLLQQIFIDLNLVSKFSIKMETLQSYLFEIYSNYNDVPYHNF
RHAFVVTQMMYSLIWSTKLFDLIGSLEILALIVSALSHDLDHDGFNNNYQINAQTHLAMI
YSDKSPLEMYHCAVAFHILNKPESNIFSQLDKESFKKIREYIVQ
>A0A3M7Q0U2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Brachionus plicatilis|TrEMBL
MSNLHAKLLYVRIENRIECIEFDSNTTTEDLKETLRSAAEANQNDILKLYNHKGNLVAIN
GSLPVNISSEPYRLQVIAKNIVDYNNELKDLIERIEHLEIQLNSLSSQRVEDLHSKVKNL
CSKLENIDHLSFIGLFKDTRLYTVGTFSNEKNETKKENIQNVYEKFKSFSMVKVDDETRQ
FLKSPHFDNWKFEDAELLVLLQQIFIDLNLVSKFSIKMETLQSYLFEIYSNYNDVPYHNF
RHAFVVTQMMYSLIWSTKLFDLIGSLEILALIVSALSHDLDHDGFNNNYQINAQTHLAMI
YSDKSPLEMYHCAVAFHILNKPESNIFSQLDKESFKKIREYIVQ
>A0A517QEM2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gimesia panareensis|TrEMBL
MSLIPPDSRISLGRRAFLQHGALLLTGISATPLSRLAAATEAKQRGVVRIGLVTDLHYAD
KPPAGSRHYRETLAKLQDAVAQFEKDQPDFVVFHGDLIDSGKSLEQEKKHLETIVKAISA
MPFPKNYVLGNHCVDQLTKAEFLQGVGQQESYFSFDRSGFHFVVLDSCFKSDGTPYGRHN
FKWTDANVPALELKWLQADLEKTNLPTIIFAHQPLDLKDTDAHAVKNSSEVRKVLEASGK
VTAVFQGHSHRNKYSEIEGIHYCTMVAMVEGSGLDNNGYSTLDVYPDGSLVLNGFRKQQD
YHWS
>A0A377ZNA6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MRYAVDDFATRLLFIDSSHAGTSKGWLTDETISWLEAQLFEGGDKPATIFMHHPPLPLGN
AQMDPIACENGHRLLALVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHE
DTRPYYDLSPASCLMHRQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A378BPH1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGNHDFQPAMYSTLQEAGISPAKRVFLGD
RWQILLLDSQVFGVPMAS
>A1K307|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Azoarcus sp. (strain BH72)|TrEMBL
MNPNDVARYLRDNPDFLAQHGELFTELTVPHPQHGGQAISLAERQLYALRDKIRQLESKL
AELIRFGEENDDISEKVHRLAVALLGARGYAAVRQALFNCLQEDFAVPHVALRLWDVGGE
GTGPDFDAVSEAARLHALDLRHPSCGAPGSIEIVGWFGEAAPHIRSMALMPLRRQGETVG
VLALGSEEGERFYPEMGTLYLGRIAELCAAALLRELA
>A0A2G8Y855|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii COUG|TrEMBL
MWFYSYLRHPNDVPSLCTHIRSSNIFLRLGPQYYLPEDERKSLFVRTCHLLYYLASLLFL
TTLTTYTAIKIPSSPSTTTELLSQLFPFNSIDDCNERLSCKVDCVLYAFPDLNCAKDDGS
LLTFGGNSYSSLYFYHYPGKDVPLQKEARTAWERCYQIMRETTGRLQFLLQDRETVERTH
TCFAGCKTNGAVTFTQKLTDGTPVVFDSGTDWLQMAPAGSLPQDTRPACNPSEPPSLLCV
EPTDECQHVTLRYQVCIGDTAFCFDIVRILITIALGVVWNVVLDAFVVWAMSIDDSDPQN
LGRVASKCGLQIIATAIIVSSFFCLVASMTRILSMDANIARHGTLWTSFVLVIIIDQLFS
FLFSVLIWYAMLRRCGRQLPDESRFQYKIHPSPVLVKLKKATRKIVNYNGFEMFFTMLLG
WMVVDLTCRMILCQFFFDETAFLNQADRILEVVDFIILILFIVEICLRIAADGLKIYFSD
PINCIDFFLVFFGFGIRIVDFFIQINKGIGNVLFIMRLVRLYRLHRPPTGSLAIGKKEVF
TSRVERIIAVLNKALEIEELTTREKDSLKWLIQTISSGKLYEMGSEEKKKTDSHVQAWIS
IISTQSQSANQMADDMENILLERVKQMTKAGDAETDMPAVLQLEYGIDVSLDHAIEGYLA
NNLITWNFDVFRFHVIAGRAALPKLFVRCLQHQEVCSLFNLKIENMLRFAMELEKTSFST
TPFHNSIRSAEVLQAMHLFLAFFDTQIKGFFNSREILAALLAAVVWDYQHPGFSSAFLIK
TQHAIAIRYNDRNVLEHHHVAAAFSLMQKLGENDPLLAFPEDQYIALRKIIIQLSQSGSR
SNQTACLSLLKTKLQQAEFPRSITEDKNIILCNLMNAANYSFLGRPLQLYLQWSQKYMEE
LFMQGDRELELDMPITKNCDRHTTSEAVVQLGLIDGWAIPIYTTLAQTVPKLNAIVVSHL
RRNRLHWLDEQQEEDKSKEKQTKVTPIKRYSKTKQGSTEATGNGELSKPEATTVEIADGT
AGVPELRASANPLSEVD
>A0A2G8YA15|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii COUG|TrEMBL
MAAHSPYLGRPGTFSAPDECWNEERVPSGISPADTIREIVLFQALRNAERWSARAHVLET
KTGKTPAVSVSGFGSADASEGQRAIGSKRATPGKEDSTKSSKDSPRSAFASSPPHAHGPG
ASTPPGPQSVCGASFWTQRRLLVRHKTYSPARFGISAEDERDEGEDRLSRDEGETGALAG
SPGFPLGKRDRMRERKLKPPRRRSWMTVTENRKRREQEEQRRDDRSRVKENVLRGILKRE
KEEKKSNEGTRDGVRSSTCRHANPEQRTNREDRKGKTSGNHEMDENADRSRMSGTRKPGN
ETWGREKDLEDHQPHTCEMLPQEKEITDIAEETERGRAVESAGTLSQKEARETKKREASK
EKGKGARRHAGESMQMSQMSLETELLHVEKRVCETV
>A0A2G8Y5Q8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii COUG|TrEMBL
RTITPMFDRRKHADFPKGQEGFLRFIIIPLYEEIAAVDTTDVVQTCCLQNAVANSERWRQ
LQSSPEEFEAIDAKHQAIICVLKDRLEWRVQKNIAPTQRLLRASCAENQVRGSGVFFPTP
ECSGGSGAPRASAPAEKRRESASASRDRDPGAADWKEETGNTAQALRERPPTEVAPQVDG
EETCVSDGVHERNRQDEGGGSEEGRRKAAGGETEKQGDDRKDLLHFESRLTH
>A0A5P2ZTP7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodobacteraceae bacterium|TrEMBL
MPRIVQLTDSHVTARGRLWKGQVDTAARLRSLVAAVNKLSADLVIHTGDVVEMGPLPEGP
AEYDQAAQILAELRAPLRILPGNHDGRAAMRAAFPDQVWEGAPFLNLSLDLDGLHVIGLD
SVVEGQTAGAFPAAQQNWLSGRLDDRPTLIFLHHPPCPMGLPFMDGFAFDGGEALAATLA
GRDVLQLACGHVHCDVAMHWAGTLVAAAEPSSVLIPPDMPALDACARGTPRKAGVDPLRI
RCFDWADGALSVKTVFAEPSGMQAVI
>A0A378YHR7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Nocardia otitidiscaviarum|TrEMBL
MPMVLLAHLSDTHFDGGGRNSDRAERVMAFLAELPTRPDAILVSGDIADEGSAEEYEQAR
AVFRGADVPVLLLPGNHDDRGTMREILFDAAPGYQPINQVHRVKALTVALLDSSIPGKSE
GLLADETYAWLENLLAATPADDTVVIAMHHPPVPIKSTVVDPIPLTNPERLAEIVAGDDR
IVGVFTGHAHVPVQTLFAGKQLAIAPSVSSFIGCEWEVGVPGQVPIDFAPEPSLYFHAIE
DRRLLTSLRPVPLGGGLTEPAE
>A0A7G6VAG0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Burkholderia cenocepacia|TrEMBL
MFSAAVDSLNRIRPEPDLVVISGDLTDEGTEDEYRKLRELLVELRRPFVVLPGNHDDRGN
LRAAFPDHAWLPDEGALSFALDVGELRLVALDTSVPGLHHGELDAETLAWLDTELAEHRN
RTVVIVMHHPPFMTGIPYLDIYGLRNAEAFAAVLARHDNVDRILAGHVHRSMQTRLGRVP
VLTCPSTTTQIALRVEADAQPASFLEPPAYMLHRWAGRGQPAVSHLCYVGHFEGPFPFA
>A0A517YT92|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Poriferisphaera corsica|TrEMBL
MRIALIGDIHLYNLQLRPRQWFSRRVMGHTNLLLNRRFRFNHGLLHPLMDKIREIKPEMV
LCSGDVTTTSLESEFSDIAKFLKPLSKEIPTVVVPGNHDRYTFRAQRKLRMEKILEGIMP
DTFPYYRRLTDRWHLIGLDSAIPQILMSRGALKKKQFSAFEMQLGQLSKEDALVLLCHYP
ASSPPGIPNSWAHNLAEAHQLRKMLNDCPARVLYMHGHIHQPWYWQASHKGVAANTDCTG
ELAFLNAGSPCMTSSKYPSGQGFWEVELPQDPSKQIGLMHHVPVAKRVIGSKRPKNQDHL
TVIDGITWNSRTVL
>A0A378I4C8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Legionella beliardensis|TrEMBL
MINKNLLKNNLKIIQISDMHLFAEDESRIFAIDSNVHFSQVIEHIKSHELKDADAIILTG
DLSQDETAASYNRIVGAFNGFNLPIYWIAGNHDNVQIMQDCFKDATFFQNTPLLACNYWH
FIFINTKIPGSGSGYINEKELKFIAEEINKLKKTNKKIALIMHHHPMTINTPLMDQYGLE
NRDALWEKIADSPVQLIICGHVHGHYRFKHRNINIECSPATCFQIPKGANDLQIEQAIGY
KIHYFKANTYQSVPIIWKIA
>U6M8S4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Eimeria maxima|TrEMBL
MEGRERQGEGASMPASPTSALLGYGGSRAAAAGTAAGGGGGSGMHASSSSTPPVSFSPIL
RKSGSLTSPSLPGSTSAAATGGGGGGGAGTGAAAGTAPSSSSREEERRRDFQRIKTVSFA
NLETVGGGGAISCSLASEGDNTAAGDSAAAVPAAAAGTTTGGGGGGGGGGPPRLEGVSSP
VPAALTDDETEHHSVSAVSGAFALYPHSYNSSSSNISLYLPFGSKFSSSYLCCCCSRLCR
WCRRLGPGNDLAFHTREDLLLQQQQQQKRHGGRLTSRSSTLSSSSGGAARSNSMRGGGST
STAEKLLRPFPLMFTSNELEDLFSLNVNHWMYVRMFPMGVLLLLLTLAMWPLLAWSFDQQ
KAFDHKSNIGIMFNAAMGITMLSSAALAAAACIAKAKGYAEHLTTLAVFVLVTMWGVWNG
VASYSLEAQVDDKDEFRSTEESTALEACTAMSYLYGLLPVVIIDVVLPSRTKYSWLIHIS
FFGTSAATIVDTRRRVERLESDLKRQRSRGGASTSLEHLVQLVKQMQELNHLALSAAGES
MRAADVRLQLQESRALLQQCLSILCTTTNLYAVNFSPLDNVEHLDIIQALLNDKNALPKD
WFRRKETLPGAAGATGSPDAPTPTTRQQQPGDQNHTRSSNRSSSSSSSSSSSSGNNFTLR
SNSNTHTAHPSEQTLLEDKPHPTAADTAAAAATTAATAAAVAASAAADTHTSHGTVSPPV
GPPPLPAAAGVSASGIQPSTPPPLTSAAAAGAAAAAATAASLSSSSPPPPPSARRTTEAL
KQQQQAVAQLLPIPRSRRGSQSGEEGGGNPHEETTERNSNRSSVLSDMLLIPRRTSKATH
ERHTAGEDKLIRVSYLFSPGLTGGSTLSGSLGDWRFDVLNYGMECNSPLPEMGFMLLSYF
CIESNLCSEQTIAKFLRAIDKHYLPVPYHNALHGLMVAQKTFALLSLLSLVKSRQPRDIA
LILVA
>A0A1G4HL65|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Plasmodium vivax|TrEMBL
MNMQCNKTNPTCEISSVKDFLRNICLDQEDKIVQNLELRNVKTVYDFLRHVSYLTVTSCT
GMNNDENVDITSQSNVKFASAHESIFQNGVSVNGKLTQQLAQQLAQHNGDGGNPGEAQLC
NGHTSAGREKGDRCNGVQRNGPQGGGKLANGVSGIGVSSNGVSSNGVSSNGMDGSAGRDD
PAAHSESTQACKEIAAMRDYYEQAREKRSGAEKKGEYVYFDMYIKSEVIKTLPTTDRDKE
RLINYIYKVMDVNDLLMMCIHFGLPHLWPKFEQSNIRNVELFKRIIIEGRKFERVKNEMG
ISFSEFVQIVNFTLSVKKKRIFCNNIFSQFDPCDCKNKKKHTKTICDKIHQFIEFDNWTF
KNIIDNPFFQRLRNLSQLGVCQFVYPGATHTRFEHSLGVGYLSAKYFAHLCNRYNLSPYS
GELNKMLRCVQIAGLCHDLGHGPFSHTFESFFMNYKKEETDHKWNHASMSLKIVEHVIEN
LIDQDDVLDSTDIKIIKKLIKGREHHKSVCGVDPVDSLIEASYDIICNNRNGLDADKFDY
LQRDATIAPPNGTLPSLNCNRIISQSSVINGHITYNVKEIHPVWTVYMNRFSLFKQVYTH
RKVRVMELMLCDGFRLADDIFKWSESLHDLDAFLDLTDSSIIYDIKKRANKHKYDEKVQK
SLNLINSVIHDRNSNHAYKYISEINLSEPQLIKYLKDIANEERIARYAHGLSPDDIIIDW
NYLNYGMGANDPLDSVYFYSSDNEDEAFIAHKEYRGTHPRYFEECNVRLYCKNKMVAHLA
KDAHNKFLSDVFSESSPLYKKKIVK
>A0A5E5Q6P2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Gammaproteobacteria bacterium|TrEMBL
MKHFIQISDCHIDDNAQTMGVNSHENLIKVVDEIVTLQSDALLISGDLTHNGTPYSYKKL
KEILSPIETDIFVIAGNHDDSDNLASEFSACLFDRIALDAWDIINIDSVQIGKTSGFVTT
NALTALDQQLQHSNAKYNLIVLHHPIVAMNSEWDDALSLENPQDLFAVLDKYPKVQAVLF
GHAHESVEFDKNGLKIIACPSTATQFNDEQRIGFNYYTLFDDGRLDYETQWINS
>A0A0E1PXM5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acinetobacter baumannii NCGM 237|TrEMBL
MTFQVSTLSQKNHVIIQITDTHLLEYPQLEFVGMNPEESFHAIIQQILKQHPEADAIIHT
GDLAQAPTPITYKRYINFMQTLGLPFFQTLGNHDNVDHFPLHNENHQQPVVVGLGNWRVI
MLNSAVKGKVDGHLSSEQLENLANLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNA
LLDTLSPFQNVKALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRY
IRLNNDGSFETKVFRLENFKTRINTDISGY
>A0A3B0J7P4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Arsenophonus endosymbiont of Aleurodicus floccissimus|TrEMBL
MSMINNNNAILTVALISDLHAEDEDSLNTLQLSLQNIAKIDQVNALLIPGNIADYIDKRN
QCFNIIEQEFPKKYFSNVAIILGNYDIRWYNEANDIDPNILINYKKRNNKFSPTVYPETH
YFDHWINGYHFISLNSDQGLNDMCELSDKTLQWLEETLAVDADIDKPIFIISNQPLNNTH
WLAGLYGGFGAQDQEIKEILSHHPQAILINGHIHKGFGVIEFIQRQFGTLIEAPSLTKMQ
NENGLGDKGTGWLIKICHDKIIFEGWNFANSKIYDEYSHDLLLPSLAVLTAELKKSALDS
KKQELIIYRQKK
>A0A518DM56|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lignipirellula cremea|TrEMBL
MPAHLLAASRRQFLLAAGAGAATAVTCRAYGDDRSSTEEVVYLLNDTHIGEHQPTDSPVP
SHLRQAVEELVKREQKPACVLINGDLALKDGQPGDYRHLARLLKPMRDAEIDVHVTLGNH
DNREVFFEVLAEDRAEVPAVKSRQISIVETRFANFYLLDSLQETMKTPGVLGAEQLEWLA
SALDDRAEKPAIIVAHHNPRLGGDPAHFPGGLVDSDALWRLLAGRKQVKAYLHGHVHHRA
LAAHKGIHIINNLAISYVGNPAKSTTGWTIARLTADGMTMQTRTTDAKHAWHNEIERLVW
RS
>A0A8C8GPG0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oncorhynchus tshawytscha|TrEMBL
SITGAPLLKVHLLRCLVKQLDKGEVNVVDLRKNIEYAASVLEAVYIDETRRLLDTEDELS
DIQTDSVPMEVRDWLASTFTRKMGVVRRRPEEKPRFKSIVHAVQAGIFVERMYRRTSNMA
GLTYPPAAIAALKDVDNWSFDVFVLHEASSEHALKFLVYELLTRYDLINRFRIPVSSLVS
FVEALELGYSKHRNPYHNLIHAADVTQTAHYLMLHTGIIYPDFEHTGTTNNFHIQTRSEV
AILYNDRSVLENHHVSAAYRLMQEDEMNILVNLSKDDWRELRTLVIEMVMSTDMSCHFQQ
IKSMRNALQQPEGVDKAKALSLMLHAADISHPAKAWKLHYRWTQALMEEFFRQGDKEVEL
GLPFSPLCDRKATMIAQSQIGFIDFIVEPTFSVLVDTTEKIITPLIEDTLKSHDTGVRRS
SLTGIDLKRVRHTLAEVIQHNKDRWKELSVQGIVVFLLLLFFIFFFLVFFSLLNTFPSFS
VMFFTLS
>A0A5P9CZ79|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Labrenzia sp. THAF82|TrEMBL
MKLIQLTDIHLTTPGNTIGGRDPNENFRKALDHALTQHLDADALIITGDLSDWGDRTDYV
RLKETLSCVSVPVQLCIGNHDERDVFLSVFPERVDENGFVQSVFDLPLGTGIVLDTWGPG
SHAGYYCETRRDWLDGQLKAASGPVFLFMHHNPVPIGIAPMDKIMLQDHEAFAALVKKHR
DKVRHIFHGHCHLPLSGSLCGVPFSAPRGTNHAGWPDFANQGNLSASDLPESYAVVLVDE
ISVMVHMIEYGYQGAVRREGSPDYADWNRLTMVR
>D3NUG3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Azospirillum sp. (strain B510)|TrEMBL
MKRLAHISDLHFGRIDPRVVDGLLSDLTAQAPDLIVISGDFVQRAKPRHFEEARAFLRKL
PFPYMAVPGNHDIPVYNVFRRFTDPFGHYRTYITNDLSPLHIDDELAVLGINTARPVIMD
FSEGRMNRRQITRVREVFCGMPETVFKVLFTHHPFLPPPDLPRTQLVGRHKLVLPALESC
GVDLLLAGHLHKAYSGDIMSFHTQVARSILVAQASTATSTRLRNEANAYNLITVAHPTVT
FEVRSWEGAAFAGGLVSSYRKAGNRWTLQAQDTGFRPVGDGQASGDPATAA
>A0A161THK0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Triatoma infestans|TrEMBL
PFQFDERLADEDDELSEVQPDAVPPEVREWLASTFTRQLATTRRRADEKPKFKSVAHAIR
AGIFVDRIYRRVTNTALMQFPPEVVKVLKTLDEWSFDVFALNESAGGQPIKYLSYELLNR
YGILHKFKVVPNTLENFLAKIEEGYCRFKNPYHNNLHATDVAQTVHFMLCKIGL
>A0A8B7XDC8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microcebus murinus|TrEMBL
MEISGYDDGANVFFSRLPAGCRQVGRWMIFLNESNFCETMDKSKIHAIFKYEFHCGTNAT
WAARNIDELFGKDVANELIVSGWLEKFHSGDFNLESEPCGQPETKVDNDELKAVVEANPS
QPTCELAARLRSLVKQLERGEASVVDLKKNLEYAATVLESVYIDETRRLLDTEDELSDIQ
SDAVPSEVRDWLASTFTRQMGMMLRRSEEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLS
YPPAVIEALKDVDKWSFDVFSLNEASGDHALKFIFYELLTRYDLISRFKIPISALVSFVE
ALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTG
TTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRLLQEDEEMNILVNLSKDDWR
>A0A1V6JEB6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bacteroidetes bacterium ADurb.Bin012|TrEMBL
MKKPQHIIWCIGLLLFLLSSLKAQIPSQGFSFVFMTDIHLTRDDYAVEGFRKALAVASDL
KPDFIITGGDLVMDALDCDYQHAIDQYDLYLGTISNSPIPFYNAMGNHEIWGWQNKHLRQ
EEWEDYGKNLFKRRIGPPNYSFDHKGWHFVVINGIEYNDSTSYVGWASDETLDFIQNDLK
NVPVGMPIILITHIPLITLEAQWEKGALACNHPMEVIGNSKEVLECFPAHSLRLVLQGHL
HYYEKMEIDGIIFITGGAVCGAWWKGNYRVTDEGFVLIRINGEYCQTQYIDYGWEAMR
>A0A3R8GGX2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii CAST|TrEMBL
FICRPLFGSLAQMFPAQLGDRAAELRKNRNKWKSIIDGHERR
>A0A1Y5TU70|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Falsiruegeria litorea R37|TrEMBL
MKIIHISDIHLTLPGEEMGGLDPHARFARALADVARNHPDAARIVITGDLTHWGEEGAYE
ALKAAVAGAPVPVCLMIGNHDDRATFRAVFPEHPVDANGFVNHAETIDGVRFIYLDSVGD
KTHAGHFCAKRRNWLRAELEGCDRARIFLHHNPMELGLPAEDKIALVAEDRPGFRALLEE
FSDRIDYVHFGHVHAPIHGRYAGVQFASVPSTGNQSIPDLNEAELLQGAPMEPGYFVLLI
NGDDTIIHQVPFDWSGPVYTAGTEWDDWAKPDAAAAE
>A0A2K8KKH1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Reinekea forsetii|TrEMBL
MPRAHTLVQITDPHLHGHAEGTLLGMNTERSLKLILELVQSEVADIDLIIATGDIAQDSS
LQAYQNFLSFLAPLPAPMRWIPGNHDNPSHMAIAGKGLDHAEAIVDLGEWVVVLLDSTVT
RRVHGHLAADQLAILEQALIQYADRHVLVTFHHHSVSLQSRWIDQIGVRNNDELKALLDQ
HSCVRAVVCGHVHQASDQVVDGVRYLSTPSTCVQFQPLSQDFGIDPLGPGYRKLVLNPDG
TIDTAVSRIDGVDFDIDFSQTGY
>A0A7U3YZU7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serratia sp. AS13|TrEMBL
MNKVLALCLSGYSALALAGFDEVALGVDGGVSDGNLTSYLIRSDNQPQYLALDAGSLLPG
IAKGLEKGSFPQVTPELAAPYTPQGYVFRQLIGGYFISHGHLDHVAGLIIASPEDSKKNI
YAQADTILTLRNHYFNWKAWPNFTDAGNGSRLGTYRLQTVRPQQRFTLGVTGLSGVMYPL
SHDRYSSSMLLVSDRSGSFAYFGDTGPDALEQSRNLDTAWRALGPLIEQKKLKGMIIETS
YPNGVEDKNLYGHLTPAWLLKELKSLAQYSGGEGSLKDFPVVISHIKPSLKQGEDVRATI
KQQLDQGNDLGVKFILMAQGDRQTF
>A0A376KPK6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cronobacter universalis NCTC 9529|TrEMBL
MIIAQLSDIHAAPDNGHLARFDNALAWLKPFEPDVLVISGDLTDDRWRDGYSAIAARLET
LSCRTLILPGNSDDRAVMRAVWPSLAQQGPLHAVVDTPALRVIGLDSTVEGSAAGSVAAH
LDWLAHQLDQAHGRPTLLFLHHHVFMSGIPSMDAIACRDAHALGTLLHHHPAKPLAIATG
HVHRPASGMLAGIPAYICGSICPANPLWLGDAHVPAVCDPPALMVHRVENGALASHFIAV
SPVNGR
>A0A6J4SGQ8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Solirubrobacteraceae bacterium|TrEMBL
PAGRRVHAARDLGRSRRGRRARARAGRRPAPPHGPRAGRGARTRAGHARPAHGHPRARRR
VARAGGVPGPLRRRVLPGVPPAGGALGPGHGRGRRRPGRPRPRRAARHGGHRRQRPGQRA
RAGAGGPPGRPRGPRLRRPRVPRHPAGHEPRPVLLPPGRRPARPAGPAPPGLAPVHGARR
AGPVVRRAGQPRRARRGRGGAHGGHHRPGGGRRGARAPRRGPRGPPRPGPGAGDRGRAAV
GRRPARGDRAGGSRPGAPLPHAGAGPRAPAGRVGPRDAARGSRRPRHERGGGPRRARARG
PARPRAAGRGRRRRRDPGAHRVPRRRAGRRGAALGAGGHPPAPAQGARRRGAAGPDGPGA
ADARRARRGHPPPPHHRAARPRGRVLARGDRGARRLPPAGARPARARDPGRRRGARVGGR
GHRSRPARRRGSRAGVPRRAGGPAGGQRGPPGGPQRAPVPGRPGL
>B8BST1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thalassiosira pseudonana|TrEMBL
MVLERYVEEVLKRHRKDCYYQREFFGQKHEGETTSGEEKHSSESDDVQQNTFCEYHNWYH
AVSCAHVSFLLISLGGASAYLQPIEIFSVLLAALIHDLDHPGTNNDFEVKRNSELAERYE
NDAVLERHSINLGLSLCQKNEELDWLKCFKEGSEDRTTLEEFITECILATDPAKHADIYD
ESCSSVDEDKTTQMAYFNKHNPQHRLFIGRIILHSADISNPLHSSFEVARDWAIRVTSEF
SKQATKEKELDLPVTSFMDGLNSEYKIAKMQIGFFGFMVQPLFKTLEVLLPGAAHLEGWG
VRNCDEYHKIVDAYERENNMS
>A0A125YS94|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii (strain ATCC 50611 / Me49)|TrEMBL
MHRLLDWDFHVLALPPASAVLVTRDLLTQFALKANMDIPGEILMAFSVAIYKNYRPNPYH
NFYHALNVTQVLCLLLALPDVAAQFSPIDYLVLSVAALGHDLGHPGANNLFMTRFDCWPS
RIYQNVSVLENYHAASLFQILRHPAFNVFCSVSPTNFAPIRKRIISAILWTDMAKHFDVV
AKLQAKIQGEMVLAEGIIVTLTKPYLEGLLLHAADISNPMMDFELCRDWAFRACDEFYQQ
NKMEEMGGFPPSMPSFEHFDEYNVAKCQVGFIDAICKPLFNSLALMFPAQLGDRATQLQK
NRCVPLIIFPT
>A0A7X0A3W5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mucilaginibacter sp. FT3.2|TrEMBL
MNRKYSSIIIVICVLLPFFTKAQVKNTPAFRLVPLGVLGGIDESNLSAYMLAASGTNNYI
CLDAGTLHYGIKKAVENKAFDVPAEKVLRQYIKGYFISHAHLDHLAGLVINAPDDSTKNI
YGLQSTLETLKTHYFTWESWANFADQGEAPALKKFHYQALTPGSETAIENTDLKVQAFPL
SHSNLTSTAFLVRSNNAYVLYLGDTGPDEVEKSNNLQKLWEAITPLVKNKQLKAILIEVS
FPSQQPDKTLFGHLTPHWLMAEMDKLAALTGTNAVKDLNIVVTHLKPPANSIGKIKTELK
ADNKLQLNLIYPEQGKPLAF
>A0A1S8N241|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium saccharobutylicum|TrEMBL
MLNLQLLVIYKSLGISGTAFQRCIESDRKLLKESINLLNLAIDNILQSKANFVLISGDLT
KDGEQLCHKQIVKSLSRLIQNGIKVYIIPGNHDINNPLSCKYEKDKTLPIKTVTSTEFED
IYKDFGYGDAIYCDRNSLSYVVEPVNNLWLIGLDTCRYKENKLHKGGIIGGKIYKEQKQW
LLGILKEANKKRRLL
>A0A0M9J0R2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Achromobacter sp|TrEMBL
MARVHTLARRTDAPAMLVQLTDCHLFGEPDTVMLGVNTDASLRAVLRQIEADGKHPDLLL
ATGDLSQDGEPAAYQRLAAILGAAPALEGARIRCLPGNHDLPVAMRHELPEWSVPVTDVG
AWRVVSLDTTVPGSNAGHLPDSQLDLLEAALAEAPGRHTLLAMHHNPMQIDSHWHDSMMI
DNPQALFKLLTRWPQVRVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNLA
PGYRWIKLYQDGSMATGVRRVQDALWQATQPGPDSAQAA
>A0A086KCY6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii p89|TrEMBL
MHRLLDWDFHVLALPPASAVLVTRDLLTQFALKANMDIPGEILMAFSVAIYKNYRPNPYH
NFYHALNVTQVLCLLLALPDVAAQFSPIDYLVLSVAALGHDLGHPGANNLFMTRFDCWPS
RIYQNVSVLENYHAASLFQILRHPAFNVFCSVSPTNFAPIRKRIISAILWTDMAKHFDVV
AKLQAKIQGEMVLAEGIIVTLTKPYLEGLLLHAADISNPMMDFELCRDWAFRACDEFYQQ
NKMEEMGGFPPSMPSFEHFDEYNVAKCQVGFIDAICKPLFNSLALMFPAQLGDRATQLQK
NRCVPLIIFRT
>A0A1V5PWF6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Actinobacteria bacterium ADurb.Bin346|TrEMBL
MSENKNETVIVQISDLHVGEADFVPSLLTRCIDEINELKPDIVMITGDLTGMGYRREYDT
VKNYISPIKCRNVLIKPGNHDSRNVGYMHFEDIFGERYTSFNTNDLHIVAVDSSEPDLDN
GQIGREYYKWVKSEFSKAKPQDLKIFAMHHHLIPVPGTGRERNIVHDAGDVLEVLVESGV
DIVLCGHKHVPYLWRVEDMYIVTAGTVSSLRLRGRIEPNYNIIHIRENELDIYRRYPFDR
IEKIIGLERKTSKSKLNDGFTKEKAKFQ
>A0A0P8YEA5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oxobacter pfennigii|TrEMBL
MRFIIISDCKGKNNGINKEILTKIFKQTVKLQPQFIVALGDTVAGHPDEDVLIFQLKHLK
KLIYKYHPDITVYPVAGNHEIGSRSNDDRYEKAFSSFYGDFALDSSLQGYNNLVYFKDFE
HVRLIILNTFRFRSAHKIDEAQLNFLEAAASIEKKYKLLFFHSPAFPTGAHYGNCLDLHP
DYRNLLWSIVDKHKIHVVFSAHEHNYTRRLIDNSFLDGNFKNPIYQVITGGGGEKLRDKY
ISSQGVIIPPIARHHFVLVDAEGDGLNVYAMDLKGTVMDEFVIKK
>A0A517M041|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rosistilla ulvae|TrEMBL
MPIHKIPQSRRRFLQTTVVGGGAALLMSSTQRLSAAEADATVIALLSDTHIPSSHDVEAR
GINMTDNLQRVIGEVVDRKTRPTDLIINGDCAYLKGLLGDYQNLVSCLAPLDPAGISLHL
TMGNHDDRQPLYDALSDQRPADAQVMAKHVSVIETPHANFFLLDSLFQVNVVTGELGAAQ
IDWLAKQLDARADKPAIVMTHHTPQFTEPAEGKPWTGISDTAALMEVLESRKHVKAYLYG
HSHHWNHSQRGHFQMINLPPVAYVFNDKSPNGWVEAVLTPGEMRLELQTLDPKHPRSGET
VMVSFAS
>A0A087DDQ6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bifidobacterium scardovii|TrEMBL
MDTCVMNGSEGAGGTGTGTATAADGGEVRFERCSNARVVERRDDGSPWLIRSAAPDDLTD
ADEARLRGLGVSTIVDLREPGEGHPRHFRGITTVPVPIYRLEGGAPRTGTLEGIYAFMLR
HRGADLARAVGAIADAPGAALVHCSIGKDRTGLVVALARLAAGSAQQGIIDDYALSGGRL
GDAIRRRTLEEVDQDAPGEPEHSDTLRMRLDSPVSMMASICDQLQGPQGAVRYLLRNGLA
QTQLAALRGKCASAGRLTILHLSDLHAEQPPARLFGHIDSLDAVAKVPDYLRSLAVRPDA
IVVTGDLIHHDVRAYRRVCEALQRLSDDLGAPLCVVPGNHDDVDAAADALGRYTTAAVAP
QSFGVRGYTLHLLDSSEGYIAPEALAGLRKSLHAPCAGDGADQDGAGLSGRDSASGNCGG
PSILVMHHSPVGSLMPSLRHIALHNADALADAISGADVRLILAGHFHHAMQGVFHGVPVC
VAPSMAYEQRMDAGTGLVEGRSGTAFSIEELGPEGLRVTTVPMSLADDTLFSVPAGTSTH
PGHQHHSRPSVELAAAR
>A0A4Z0YI43|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Caproiciproducens galactitolivorans|TrEMBL
MSLFAIADLHLSLGCDKPMDVFSGWQNYTERLEKNWRAVVGRDDTVVIAGDISWAMNLEE
AVNDFSFIHSLPGKKLILKGNHDYWWSTRKKIVEFLERNGLDTIQIIHNNAVVVGDIAVC
GTRGWLYNAETDEDVKIVNREVGRLNASIDDAERQGAKPVVFLHYPPVYDGAVCKEILDV
LKERGIQKCYFGHIHGSQAARRAITGEYEGIKMVLISCDYLNFMPVLV
>A0A1S8TKC8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium sp. BL-8|TrEMBL
MKAGLIMKIPLKFDNNRNFKIVQFTDIHEGPEKDKSISLMNRILDCEKPNMVVLTGDNID
GKCKTVDDVKKAINNIAGPMENRRIPWAVVFGNHDDEHGMMTKEEMMKLYMSYKCNLSEI
GYKTFDRIGNYNILIESSKRKVPKFNIYMIDSGKYAPSFIGGYDWIRLTQIYWYRKTALN
LKRNYNRTIPSLMFFHIPLRNFKKAWETGFIDGERFEEESVAKINLCLFSKVIKTGDVKG
IFTGHDHLNNYCAELNDIRLGYAGYMGYGTYGNDDIPRGARVFLINEESPEDFKTWVRR
>Q5FJY1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM)|TrEMBL
MITKERNTEFWVISDTHLIADSLHDEGPAFSRMQKTSQGKDLYYQEVALTAFMRMAQRKK
PAAIIVTGDVTFNGERVSAEKFAQIFKPLKETKLLVLPGNHDIFDGWAREFRGKKQFYAG
EISPMFWRSIFDKSYREAEDTDPSSLAYSVQLNPQYFLVLADSNLYGKEETTAAPHTRGI
IGDEQLKWIEKQFRYAQDNQLRPILFMHHNLYVHNPAVNKGYVVDDAAKLRRLCTRYNVK
LAFSGHIHAQNILGPQDFTPTTEIVTSSFCSNDQGYGVVRVHSRHITYVRRNFDMTRYLT
EKDKQNYTLEHFHKYLKNLQLGSISADMMQSELNKYHGDVNLVREMGKLFGWMNYHFFTG
HNYIKQNELKKIYVSKAYKTLIEHHPEYRLYLKTLYDTSAHSNLQVKIKY
>A0A517QUK9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thalassoglobus polymorphus|TrEMBL
MPIHLGSQSRRLFLKNVSAASAAAVMSTTLRADEKATNIDDRFFALLSDTHISQSPDGTA
RGINMTDNLKAVVAQIGQLPKRPANLMINGDCALSKGLPAEYQNFADCVKPLDDMGVHLH
LTMGNHDDRETLYEHMAKSRPAENPVPVKHVGVLEGQFANWFLIDTLIRPGHVAGEVGFE
QLQWLTKQLDARPDKPAIVMGHHNPQFTKPAKGGRWTGLWDTDALIEILQARPNVRALFY
GHSHQWNRQKVGNLQLVNLPAVSYVFSEGVANGWVSAHLDEKSMKLQLHTMDPAHRQNNE
QFEFALT
>A0A8C8A3P7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oryzias sinensis|TrEMBL
LKLTGLFNFRTDSVLIPTSYFSQRQCLDSEDDLQQLQSDGVPSEVTDWLASTFTQRIRQP
PRGVDEKPKFRSIVHAVQAGIFVERMFKRAYTAAMPDQPAAVVNCLRDVDRWSFDVFALN
STSSDHALQALFFELITRYELNTRFKIPISCLTKFLSTLERGYCKHNNPYHNHIHAADVT
QTLHCLLLRSGLVHWLTELEVLGSLFAAAIHDFEHTGTTNNFHIHTKSDLALIYNDRSVQ
ESHHLSAAFRLLQDEQVNIFVHLTREEWM
>A0A1S8M9A7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium roseum|TrEMBL
MNKIKFLFLFIIALIITTILVSTPESTSKVSADHTLQYSFSVISDTHIGVDESKNSSKIA
KNKLAIALKCIEKNFPKDKCIVINGDVVDNYYESSYNELTNTILSVNYSKKLPYIYFNLG
NHEFKYNGEGPSISECYNENLNRFINKTQNIQSKLTANKDISHTFRSTNKPYDLQYVGNT
PFFFLGSDSVVKGKTNDCAYLKFNDQLKSLNDSIGTGLSFIFCHQPPLNTVKGSNASNCI
SNTDELLEVLKKHPNAIMFTAHTHRTFDNSPLTFGNNYSKLGSCPVITSPSVFRSLEGIH
VNVYEDMISVEGVKYHSDYHCTTKPDWCITFR
>A0A132BTF8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Tritonibacter horizontis|TrEMBL
MKILAFSDLHLVAPLAADLVAASVKADLVIGAGDFCNMRQGLPRAMEMLAGIAAPMVVVP
GNAESIEELRGCALPSMTVLHGQAALVEGLRIFGLGGGIPETPFGDWSFDLSDEAAARVL
AQAEEVDILVTHSPPTGAGDTTSAGLSIGSDSIRAVIERVQPRLALFGHVHDCWGYRGEI
GKTHCANLGPTPNWFEVAL
>A0A0F0KE54|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium oxydans|TrEMBL
MSAGSGSPYAFGRHELASHSLIHVSDPHFLAGGAKLGGRYDVEENFARTLEAIRAVHPNP
TAIVVTGDLADLGEPDAYRRLRAAVEPVAAELDTHVVWVAGNHDERPALRAEMLGLEPTE
EPVTGIWDLDGVRLIALDTSVPGWHHGDLDEGQLTWLAEVLADPAPSGTLLAMHHPPLPS
HVPLFDILELRHQDELADVIRGSDVRGILAGHLHYSSHGTFAGVPVSVASATCYTMNVAR
PAAEVNGMDAAQAFQLVHVYADTITHTVIPVTGAETGEYFSEAWLERMARLSPEERLEAF
SRKPAR
>A0A151AS20|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium colicanis DSM 13634|TrEMBL
MGEKNLKSKRIIILGDSKGKDDGINKKILNKVFKQIKELKTQPEYIIHLGDSVAGSSDVR
IFKYQIKEFHKLIEQYYPINRLLPVLGNHEVNNKPKDFQGEEAFEECYSSIDVDNYLKGY
HKTVYYKDFDNVRCIFLNSFHYGELFRITGRQLEWFRKVTKDLIPFKIVFVHLPIYPTGA
HLTTCMDAYIEDRNTFLKALEESNVSLVFCGHEHNYSRRLIGFNDKKIMQIITGGAGEKL
RNSYKDKKDVIVTPKPIYHYVILDIEEDNIRVRAVSLRKKVFDDFSVGIGDGSQIFI
>A0A1V5Z2D7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Hydrogenedentes bacterium ADurb.Bin170|TrEMBL
MCNCRFVFLAGCLAFCALTAQARNTEGALDLIRVPNNGQPVQVLRESTFEVIVREACELS
LSGETGVYPMAVTWHDKRGDRVSGSAVVPSHVPSGTYALQGECQNIRDVNLRSVYVVDAF
PDAYALAHITDMHTGSGRHKRSDRDILIELIQQVNAAEAQFALITGDVTDGGTPEEFRRF
LDILDTCRMPTYITPGNHDRTGTHYADYFERLTYAFQYGRDGYLSFDTKDYLIADEMGVQ
SAHLYLYRRQLRPCRWSIGLTHRYDPGMGIHAQLTLFVDDPLDYLLVGHTHREARMDDQI
PWGKTDLIMTPAAINGSWRLIRVDSQGLHPEATVSTVSVFQEKDELQDEEREDQ
>S7XCP5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Leifsonia rubra CMS 76R|TrEMBL
MIQLGQYPAPSHVIAHISDTHLLAGGKPLFGTANTIAHLEQALAQLERSTAHPQAIVFTG
DLADLGEPDAYVRLRGIVEPAAARMNAEIIWVMGNHDERAHYSSLLFDTESDAPQDRVYM
IDGLRIISFDTTVPGYHHGAISDAQLQWLSRELATPAPHGTLLAIHHPPIPTPMLEAMGM
LELQRQERLAEVLRGSDVRAILAGHLHYSTHSTFVGIPVSVASATCYTLDLSAQDRLLSG
VDYGQAVNVVHVYEEQTVHSIIPVGDTTEITGHSAEAWAQIEAMTPEQRLETFSAKNSSF
NAH
>A0A2X4W4G5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lederbergia lenta|TrEMBL
MSKNPIIEFFVISDIQLTVNNKKSHEKLKFALQDIHAINPNPDAIIINGDLISDGRSESY
LKLKEILESNAYAKRTFFTIGNHEYFLNDGNQPSIERFLSFANLDQVYYKQVLEDYAFIF
LGTESWGPIGAPTKDSAVLSEAQLAWLESALEEHRGSEKPVFVFLHQPIPNTIPATDLEY
YQNGIIQSKELIDILSQYPQAIYFSGHSHWDLSLPGTYLRKVFSMVNTGAIYDTYGIGDN
GEETVVNAEGSQGLYVQLYKNKVVIKGRDFSKKGWIDLADIAFNGEKELSC
>A0A1S8T325|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium puniceum|TrEMBL
MALYTISDLHLGFNVEKPMDIFGVKWKDHCDKIKENWLSKIKEEDMVLIAGDISWSLKEK
DSKYDLDWINELPGKKIISKGNHDYWWGSISKLNKMYENTKFLQNNFYVYEDYAICGTRG
WICPGGDKYSAKDEKIYNREQIRLRLSLEAAKTQGFEKFIVMLHYPPTNEKFEESEFTKI
VKEYKVEKVIYGHLHGPVLLGKLLNGDFENVEYILTSADYLDFNPKRIL
>A0A0H4W4V5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bordetella hinzii|TrEMBL
MPQNPLAARRHEAPALLVQLTDSHLMEDPEALMLGVNTDASLRAVLDLVRRQEARPDLML
LTGDLSQDGSPAAYQRLRAHLRDATHPVRCLPGNHDAPQVLRQELGDWVQPVHDLPGWRV
IMLDSTVAGQDLGRIGPAQFDLLDQALRDAGERHVLVALHHNLARVDGNWHDPMMVDNAA
AVFARLSSHPRARIALWGHIHQEFDCRHHHLRMLGTPSTCFQFMLKDGRHAIDPRAPGYR
WIKLYADGSIATGVRRLDAGVWAALRGQAAPQARAA
>A0A379I6J4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas fluorescens|TrEMBL
MPSVATVNPEAPALLVQLSDSHLFAEACGTLLGMNTRDSLQRVIDLVRARQPQIDLLLAT
GDLSQDGTLESYQLFRDLTQSIGAPARWIPGNHDEPQVMARATMGSALLEPVVDVGNWRI
TLLDSAVPGSVPGYLAEPQLQLLAQALSEAPSRHHLVCFHHHPVPIGCAWMEPIGLRNPE
ALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKVSEQAPGYR
WLRLHPDGLLETGVERIEGFTFTVDYGSNGY
>A0A0B7D2N8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEADGSLLGMNTRQSLQKVIELVLGQQPRIDLMLAT
GDISQDGTLESYQQFREMTAQIDAPARWIPGNHDEPMIMAEAAVQSALLESVVDLGNWRV
TMLDSAVPGSVPGYLQDDQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQARAVLWGHVHQEIDRQRNGVRLMASPSTCIQFEPGSEDFKVGEQAPGYR
WLRLLPDGRLETGVERVTDFAFTVDYGSNGY
>A0A0D0TPQ6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas fluorescens|TrEMBL
MPSVSNVNPDASVLLVQLSDSHLFAEEGTALLGMNTRASLQRVIELVREQQPRIDLVLAT
GDLSQDGTLESYQQFRDMTRAIGAPARWIPGNHDEPQIMALAAVHSDLLEPVMDIGNWRI
TLLDSAVPGSVPGYLQDQQLQLLAQALSEAPNRHHLVCLHHHPVSIGCAWMEPIGLRNPE
ALFAVLDRFPQARALLWGHVHQEIDRERNGLRLLASPSTCIQFAPGSEDFQVSEQAPGYR
WLRLHADGGLETGVERLRDFAFTVDYGSNGY
>A0A1U7M6Y2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Tissierella creatinophila DSM 6911|TrEMBL
MIYGIGDLHFDYSKEKTMDIFGDNWIEHEEKIIEVWKEKVNEEDLVLIPGDISWALKLED
AYFDLKRIDDLPGKKAFIKGNHDYWWQSIKKMNDLELKSLFFIQNNAYHYKDIGIGGTRG
WSSRDCDFFDEKDEKIFKRELLRLENSLSCIDGDCKFKIAMIHYPPFDMNLKPNEFVEVM
KEFNIDLCIYGHLHSEGHKYVVEGEIDGIDFQCIASDYLKFELKSLYEE
>A0A3S4YEY8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serratia fonticola|TrEMBL
MLLLDSQVFGVPHGELSEYQLEWMERCLEAYPERYTLLLLHHHPLPSGCTWLDQHSLRNP
HTLAAMLWRYPKVNTLLCGHIHQELDLGWHGRRLLATPSTCVQFKPHCTNFTIDDVSPGW
RYLDLLPDGRVETQVFRLENDDFRPDMDSDGY
>M5TTM8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodopirellula sallentina SM41|TrEMBL
MLPEITALRRGVSRVRIPQSLDVPMTQRVRRIVDTAPIRHLSSISQLGLVSLVYPGATHT
RLEHSLGVYSNALRLLDHLASFDSPTNEIVSQASVAQEAFIVAALVHDAGHWPFCHPIED
MGNLSSRRADGSNILAIKHEDRVDEILRQTEIASCLEQDWACCADDVMAILRPKSLPERP
GCQLSAADVSFYASCLSGPIDIDKLDYLQRDSLHAGVPYGRNFDAERIIASLCIHPTEPK
LAITEKGRTAAEMMVFGRYVMFSEVYWHHTVRAATAMLQRVLFSLLHESSPVHKSPPVHE
DESQNAATQQTNSSSDDSLQNIASWSHLSEPEWIHRLRTAAAQPCKQSESSPTQQARAAL
AEGLFGPTRGLWKRAAEFNVESGGEVHSLLARRPYWWLVACSRRLAQRISRAINRDVDPA
MVLIDAPPVKLEVDINIDVVGRSVAKANAAVMTLGDVSPVASVLANRQFDNHVKRVRVFV
PEDIRTDLRRHSENLHAAMEDWLTRAAEEMENEIA
>A0A1C3L3D3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Plasmodium malariae|TrEMBL
MLRCVQIAGLCHDLGHGPFSHTFETFFMNYKKEDTENKWDHASMSLKIAEHIIENLIDQD
DMIDVSDIKIIKKLIKGREHNKSTCGLDPIDSLIEASFDIICNNRNGLDADRFDYLQRDS
AIAPPNGTLPSLNCNRIICQSAVINGHITYNVKEIHPVWTVYMNRFSLFKQVYTHRKVRA
MELMLCDGFRLADDIFKWSESLNDLDSFLDLTDSSIIYDIKKRAQKVDCDEKIKNSLKLI
NSVIHDRNSEYAYKYISEINISEPKLIKYLKDVTNEDRIARYTHGLSPDDIIIDWNHLNY
GVGANDPLDSVYFFSSDNENEAFIAHKEYRGTHPRYFEECNVRLYCKNKKVAHLAKEAHL
HFISNDVFSETSPIYKEILK
>A0A198XWA8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moraxella catarrhalis|TrEMBL
MPNITNNRTFNIVQLSDLHLTGDIGQAPSYQRFLAVFQTATHLNPDLWLLTGDLVNDGNS
DAYDWLFNQLKATKTPYLAVAGNHDVTHEIGIHLAHQERIHVPILPDQRLKNCFRYTFQA
GHDWQILLLNSSVSGEIFGLLTHETLLWLDQTLTTHSEQTIIALHHHPTKVGSDWIDAHL
LKNHQDFWHVIKKHAHVHTILCGHVHQVHTLYPLPTHQVQLLSCPSTDRQFMPFVDNFQI
AGTPAGCRMIQIDNKGIVSSYIQIVQNTHLFCLNNAN
>A0A8C9FC26|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pavo cristatus|TrEMBL
EVSLGIFFFTLYFPSSSRRLLDTEDELSDIQSDSVPSEVRDWLASTFTRQMGMMLKRTEE
KPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIGVLKNVDKWSFDVFALNDASGDH
ALKFIFYELLTRYDLINRFKVSSYKTGLFFHLAFSCVSFLFCIVPFRVWFLCFFFLASLI
VMPFKREFRALVIEMVLATDMSCHFQQIKAMKNALQQPEGIDKPKALSLLLHTADISHPA
KAWDLHHRWTMSLLEEFFRQVKSHPGPSGPTCAGTSTAGFIDFIVEPTFTVLTDMTEKIV
TPLIDEASRSGMSGFRRSSLNSISPSEVKRSSVKSTGSEGSASLNCSILTVDFKCFKATW
TEVVQQNREKWKAQATKGNIQASYCLSTIRLPESCLCKLPLISRMISKAREAHI
>F3BN68|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudoalteromonas distincta|TrEMBL
MAWFDDTYTFDKSSLCIAHITDSHLFADKNGEYFNANTAAHFEQALAHIAEQPVDCVIFG
GDLTQDHSFESYLLFSELINASDITCPVFWVPGNHDELVMLNRISGGKINSAKHIIANGV
ELLLINSKGPTPAGWVTGAHLDEITDTLVNSNNSKVIFCHHNPLPINGYLDKHLLENGPQ
LLNILVNSNNVSALFHGHVHNDYEQNFRGLPIYASPASSVQFVKYTPKWEQKNAGPAYRM
LNIKSKKDKVEVKTEVVWLSA
>A0A1U9ISW1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Helicobacter pylori SS1|TrEMBL
MQVYHLSHIDLDGYACQLVSKQFFKNIQCYNANYGREVSARIYEILNAIAQSKESEFLIL
ISDLNLNLNEAEYLQDKIQEHRLQNKNIQIQLLDHHISGKEVAESFHWYFLDTNRCATKI
VYEFLKKHYALLEPKNTTWLEPLVEMVNSVDIWDTQGYGFELGKVCMRMINQSSELNRFM
FDDENRDYKLKLLEEVKNYLFLENAPVAYDNDLFRLKKIALGGDPNTETMDNISSNAQTH
LLSLKKHDCSVYYQDKKGFLSYSMGGISVLANLFLTQNPDFDFYMDVNAKGNVSLRANGN
CDVCELSQMCFNGGGHRNASGGKIDGFRESFNYRDIKEQIEEIFNNA
>A0A4W4HN46|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Electrophorus electricus|TrEMBL
MHSIITFIMNGNQSVEQSLDMEDQLQELRPDSVPKEVHNWLASTFMQQARRPLRYPDYKP
SFRSIVHAVQAGIFVERMFRKMSSTAMTDQPLAVVNCLREVDRWNFDVFALDVGSSGHAL
KTLFTELMIRYELNSRFKVPISCLMSFLCELEQGYNKHNNPYHCQTHAADVTQTLHCLLL
RTGLVHWLTELEVLASLFAAAIHDNEHTGNTNSFHILTRSDLAITYNDRSVQESHHLSST
FCILQNEQMNIFTNLSREEWVELRSLVIEMVLATDMSFHILQVKAMKHSLQQQERVDKAK
ALSFLLHTADISHPAKPWVLHSRWSKALTDELFRQGDKEGELGLTISPLCDRNTAPVAQS
QIGFIDFIVDPTFSLLMDMAEKIIIPLVQDNPEPPEPINRHSNCVSLSAFDDSGAAGNFL
DTGLAAQLGITTLTLEPPLHVNSINRQPIGEGAGKHQTALVTLKVALFHSELIHFMLLPM
SSDSIILGFPWLSTHDSSISWSGAELLSWSKHCLQHCMSLPVLSTTVEGPESPYSQSIPL
PI
>A0A080VMZ0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas aeruginosa|TrEMBL
MSRHSNTPATDASVLLVQLSDSHLFAEDGARLLGMDTAHSLEKVVERVAREQPRIDLILA
TGDVSQDGSLDSYTRFRRLSSPLDAPLRWFAGNHDEREPMQRATEGSDLLEQVVDVGNWR
VVLLDSSIPGAVPGYLEEDQLELLRRAIDSAGERFLLVSFHHHPVPIGSDWMDPIGLRNP
QALFDLLAPYPQVRCLLWGHIHQEFDRQRGPLRLLASPSTCVQFAPGSSDFTLDRLAPGY
RWLRLHDDGRLETGISRVDDVVFEVDYDTAGY
>A0A0N4W894|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Haemonchus placei|TrEMBL
MKTRTFVGVAELCNKTGRTGFTRHDEQKARTFACLLYRKVQEAQRRSHMAAELLVQGSQL
LVCFLLFIFSIFHSIDLGFTARYSMNKRKLASFILRVAKGYREVPYHNWSHAFSVAHFCW
ISLRTPAVLHGLDELERLALLIACLCHDIDHRGTTNAFQLQSKTPLAQLYSSEGSVLERH
HYAQTVQILQMSECNILHNLTRTQYQTVLSHIRDVILATDIAVHLGKVGRIKAMVDQGYD
PLSRDHHYLFMCLLMTSSDLSDQSKDFRNSKAIAENIYREFFSQGDLEKQMGASPMEMMD
RDRAAVPKIQLDFMDTVALPVFEMVAKVVPEGQSTFEAISLNRQCWAALDEILVERGNRP
VLGLDYLRDEELEEQVVERVRQRKSQQKKVGHSKFSSLYHDSCRRDY
>Q8VIE3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rattus norvegicus|TrEMBL
MTPQAPLHLLDEDYLGQARHMLSKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNSHGLIHH
FKLDMVTLHRFLVMVQEDYHGHNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGL
LAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEM
TQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLENIQDRHFMLQIALKCADICNP
CRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDSIPSIQIGFMTYIVEPLFR
EWARFTGNSTLSESMLNHLAHNKAQWKSLLSNQHRRRGSGQDPAGTAPETLEQTEGATP
>A0A376H526|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Enterococcus gallinarum|TrEMBL
MNLLHISDIHFRRQYPDCQEGYQGMLAAMQNPLIPLTECLRHAQQRATIDLVVISGDLTE
DGDVEDYRYLKEQLHRLLGDVEIIVTLGNHDIKSNFHIGWCGTAASESPYNQVKCYSDMA
IVAFDNSRYGASDGVVDEQQFHWLQQTLAELKNLPIVLVTHHHLLAHQSTTPVWPGTDRL
LDLLSSYNIRCILNGHTHHSFTGEIQGIPYYTVASMSFVGEDEGQGIVRFEERYGYNLYR
FESGKLIHQTSENYLPNRLLKVVDMTQE
>A0A0R3R5R2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Brugia timori|TrEMBL
NVFSELEVLASIFAGAIHDVDHPGFTNHYLINTNSELAIMYNDESVLEQHHLAVAFKLLQ
DSNCNFIVSLNKKQRQLFRKLTIEMVLATDMSKHMSILADLKTMVEAKKVAGSSVLTLDK
TDRIQVMQTMIHLADLSNPTKPIDLYSIWVKNIMEEYWRQGDRERDLGIDISPMCDRNNI
TIAKSQVVTKNYYIYQ
>A0A0C7KAR6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFID
SSHAGTSKGWLTDETIGWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A853SVF8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Janthinobacterium sp. HH102|TrEMBL
MRLLILSDLHHELWRDEAPQGDLALSRPDAVILAGDIDTGARAVAWAATAFAGLPVLYVH
GNHEGYGHHLDKVRQELRAACTATPNVHFLDADTHVFTDPAGSKVRFLGATLWTDFRLLG
DDTRQAAMRDAEAVMNDYKRIRLASMGFRKLRAADTAMFHAQQKAWLARELAQPFDGRTV
VISHMAPSLRSVDDAYGSEGCSPAYASRLDDLAAQADLWVHGHIHVSRDYRIGPCRVVAN
PCGYKTRSGTPQNPQFNPNFIVELPLR
>B7PKQ8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ixodes scapularis|TrEMBL
APSKTRTCAASNPPSSKKRSGGFLRQAKSRKDHPADLEPVNEDELTKKDAITPDDVLRLQ
KITENYLCAPDANVHDIDFTRFKIRDMESGMVLFEIAKPPPPSTPDLECEAECQDPNAGR
FVRYQFTPQFLKLKTVGATVEFTVGAKPVSKFRMIERHFFRDKLLKTFDFEFGFCIPNSK
NTCEHIYEFPSLSQDLCDEMIANPFETRSDSFYFVDDKLIMHNKADYAYNGGLQQ
>A0A8B9LMP4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Astyanax mexicanus|TrEMBL
MGLMLRRSEEKPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYPPSVITVLKHVDTWSFDV
FALNEASGDHALKFIFYELLTRYDLINRFKIPISALVSFVEALEVGYSKHKNPYHNLIHA
ADVTQTVHYLLLKSGMHWLTELEIFAMIFAAAVHDYEHTGTTNNFHIQTRSDAAILYNDR
AVQENHHVSAAYRLLQDDDEMNILYNLSKDDWRELRTLVVEMVLATDMSCHFQQIKAMKN
FLQQPEAIDKPKALSLLLHTADISHPAKRWDLHHHWTTSLLEEFFRQGDKESDLGLPFSP
LCDRKSTMVAQSQIGFIDFIVEPTFTVLTDMTEKIVTPLIDEASSSGLAGFRRSSTKTKQ
KWQKTNPSVSLKTFLSSF
>K8CXX9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cronobacter sakazakii 696|TrEMBL
MLAGIPAYICGSVCPANPLWLGGAHVPAVFDPPALMVHRLENGTLASHFMAVSPVNGL
>A0A1Y5S1S1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseovarius litorisediminis|TrEMBL
MKKLLVFTDIHFVPEGETIIGLDPAERFAMGLGHALKNHADAERIIITGDLSHNGHRDEY
KRLRTVLENCPLPVHLMVGNHDRRQPFLEVFPETPITEGGYIQQVVDIGHDRLILLDTQN
EEADDTHSGHMCAHRLEWLEKTLADAPDRRITVFTHHPPILTGFKGMDWIGFHNRAEMIT
RLTAHGNIAQIISGHVHRTILGSAGGIPTAIFKSTCHQMPMALGYQDSSLAVDEPGAYGL
LLLDDDGIVVHTEDFTLPETEISIYN
>A0A1Y6JRB2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas viridiflava|TrEMBL
MPSAAPSSSVLLVQLSDSHLFAEADGTLLGMNTRDSLEKVVERVLAEQSDIDVVIASGDI
SQDGSVESYEAFRRLSGQIAAPARWFAGNHDELPQMEQVAQGAGLLEPVLDIGQWRVTLL
DSAVPGSVPGFLAESQLQLLAQSLSEAPDRHHLVCLHHHPVAIGCEWMAPIGLRNAEAFF
AVVDRFPQVRAVLWGHVHQEFDQMRQGVRLLASPSTCIQFAPGSEDFKLDTLAPGYRWLR
LHDDGQLETGVSRVVGMVFEADYGGTGY
>A0A7H4PB78|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella grimontii|TrEMBL
MLLAQISDTHFRSRSQKLYGFIDVNAANADVVSQLNALQERPDAVVVSGDIVNCGRPEEY
EVARQILGSLNYPLYLIPGNHDDKALFLEYLHPLCPQLGRDAQNIHYAVDDFATRLLFID
SSRAGTSKGWLTEETIKWLESQLFDGGDKPATVFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQAIISTIPGTVHQVPYFHEDTRPYYDLSPASCLMH
RQVDEQWVSYQHPLTHYAGPWMYDENISCPTEDR
>S7UZ05|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii (strain ATCC 50853 / GT1)|TrEMBL
MHISCVKGRIVARQIDNVFTVIFAIEVLGKFVSYGLEYLQDPIESFDTIVVLTSFTLLVL
GFYVSGIGLLRILRLLSALALLHKYPDSKEKRPELSAGNSSKLEKASSIVEGLLTNVHIP
KYFKTELEWVWDSILANKVYDSHVVENEEEEEDQATETIIAGSDASRKTQAAVRASRAQS
RASKLPHGSSSMVVGTTNGRISGQILETLREPDPRMMDAALYKSETRNLDPLTATVGGMK
NSPSMFAKGSKSSNMMGSSASKSFRTERNKKAIDIISVLYQASQITGAEQEQVNEAMRPF
DEWQWDALHAGDVCDMNLLPVVFVRAIATFPTIMTKFNFDLDRLFDFLKVVQTSFQKNVK
FHCAAHTADMIQAMHYFLTIGKLGALLSEYDVFLCHFCALVCHFGHPGVTNTFLVKSRHP
RAIRYDDESVNENYVASAISCLVAREEYNFFGDKLPLWQVFRLHMIDILLNFDISKSAHQ
VAMFRTKVSIKFTASTPADKQLLLTILLRAADYSFTCRQLALYSKWKDRMIDEFFAMGDT
EKQLALTVSPFCDRELTNVDKCHVAFAEVAVKPLMTVLVLGLAPHLQKDVLDTLEANQKN
LMQKLDKSD
>A0A160T4J2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Candidatus Promineofilum breve|TrEMBL
MPPVYFVHLSDTHFGPTEGYSRQGHRSLPYARHVIDLINNLPTRPDFVVHTGDVTTHPTE
AAYRLAAETFAALDAPIYYCTGNHDRSSDIHRYLPMGPKEDCQPGTDTLSYTFEVRGERF
LVLDARGPDQIDPHGLLSAQQMDVLRREATPDGPPLTIFTHYPTLRLNAPWMDANMLIFN
GEEMHQALLPARGRLRGVFYGHIHNSMQTWRDGILYCAAASTFAGFTTWPTEEMIRADHD
AMPAFNFVQLLPDQTIVQQRPFARLVGEPVRRTKENDSGSLED
>W1HYC0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae IS39|TrEMBL
MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY
QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYAVDDFATRLLFID
SSHAGTSKGWLTDETIGWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQALISTIPGTVHQVPYCHEDTRPYYDLSPASCLMH
RQVGEQWVSYQHSLAHYAGPWLYDENISCPTEER
>A0A377V9P2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella pneumoniae|TrEMBL
MESLLNLPLAGEARVRILQITDTHLFAEKHETLLGINTWDSYQAVLSAIHASQRPCDLIV
ATGDLAQDHSSAAYQHFAEGIASFAAPCVWLPGQP
>A0A086M3M9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii RUB|TrEMBL
MWFYSYLRHPNDVPSLCTHIRSSNIFLRLGPQYYLPEDERKSLFVRTCHLLYYLASLLFL
TTLTTYTAIKIPSSPSTTTELLSQLFPFNSIDDCNERLSCKVDCVLYAFPDLNCAKDDGS
LLTFGGNSYSSLYFYHYPGKDVPLQKEARTAWERCYQIMRETTGRLQFLQQDRETVERTH
TCFAGCKTNGAVTFTQKLTDGTPVVFDSGTDWLQMAPAGSLPQDTRPACNPSEPPSLLCV
EPTDECQHVTLRYQVCIGDTAFCFDIVRILITIALG
>W0Z611|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium sp. C448|TrEMBL
MSETSVASGQFGQYPPAQRTIIHLSDTHLLAENVALGGRYDTEANLRRTMERVVELGLTP
DALVFTGDLTDLGEPDAYERLRTVVEPVAAEWGCPIVWVAGNHDERPALREGLLGLDPTE
APVIGEWDLGGLRLIALDSSVPGWHHGDLDDAQLEWLRARLTEPAPLGTILALHHPPLPS
HVPLFDILELQHQERLAEVIAGSDVRAILAGHLHYSTSGTFAGVPVSVAAATCYTMDIGR
PALSVNGMDAGQSFHLVHVYDNTITHSVVPVAGAADGDYFTPEWYERMSRLTRAERLEVF
SRKPDKSGSENA
>A0A0E1NTW2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Yersinia pestis bv. Antiqua (strain Antiqua)|TrEMBL
MLLKYLSIKSASDKIKSGLLKTGVILSFSLFSSLSTAAFEVVALGVDGGVSDGNLTSYLI
RNDSQPLYLGLDAGSVLPGIARALEKGHFAAITDAMAAPLTRQGYIFRQSINSYFISHAH
LDHVSGLIIGSPDDSKKTIYASADTIDVLRNYYFNWRVWPNFTDSGSGARLGTYRMQVVR
PAQSLSLGLTRLTGEMYPLSHDKSPSSMLLISSNNEFFAYFGDTGPDDVEKSKNLDTVWR
KLAEKVTQQQLKGMIIEVSYPNDVADNKLFGHMTPTWLLKELKKLEQYSGEGQPLKGLPV
VISHIKPSFQQGQDVRKLILSELQQGNDMGIEFILMEQGDSQKFQ
>A0A8G2A4R0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Raoultella planticola|TrEMBL
MLLAQISDTHFRSHGQKLYGFIDVNAANADVVSQLNALTERPDAVVVSGDIVNCGRSQEY
EVARQILGSLNYPLYLIPGNHDDKELFLEYLHPLCPQLGSDPQNMHYAVDDFATRLLFID
SSRAGTSSGWLTDETIKWLEAQLFDGGDKPATVFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTLTQYRQAIVSTVPGTVHQVPYFHEDRRPYYDLSPASCLMH
RQVGEQWVSYQHALSHHAGPWLYDENISCPTEER
>A0A653B614|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas oleovorans|TrEMBL
MPSLPIPSADSSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIEQVQQEQPQIDLILAT
GDLSQDGSVASYERFRQLTAAIGAPCRWLAGNHDETPPMQAVCKDSELLQPVIDLGAWRV
IMLDSSIPGAVPGFLADSQLELLQRALAEAPQRHHLICLHHHPVAIGCKWMDPIGLRNPD
ALFAILDRHPQARAVLWGHIHQEFDQPRGKLRLLASPSTCVQFAPGSEEFQVGSEAPGYR
WLRLHADGTLDTGISRVTGIHFEVDYSVKGY
>A0A0N5AZP7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Syphacia muris|TrEMBL
MFKELGFIDKYKIGVTTLTRFLLLVSRGYRDVPYHNWSHAFAVSHFSYLLLRTRSVQEKL
TDLERLALLVGSFCHDIDHRGTSNKFQSDLNTRLSRMFQSKGSIMERHHLNQTQLILKRQ
ELNILNGLNEEANDIIIATDIAVHLKKTEQINKMISEGFNKDLWEHRYLLKGLCMTAADL
SDQAKDFHNSKSIAATIYREFFAQGDLEQHVFKAVPAITMDRERANLPEVQLNFLDGIGI
PTYKNLAALIPEVQETYEAICLNRKCWAKLGEILSRDGLIVKDVDYLSDNSLEERALKEL
EGGCSDS
>A0A0K0Y3W6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Octadecabacter temperatus|TrEMBL
MEKILALTDLHLRGAGQTIIGLDPTARLREALDAALNDHPDAKALILMGDLTHSGRSEEY
ETLREILQDCPIPVTYMLGNHDLRAPFRTAFPDAPVTPQGHVQHIIDLPDHRIITLDTHQ
ADVEPHHAGFLCEDRLAWLDAALEGADGRLPLVFTHHPPHAVGLPGMDAIALTNGDALLE
RLAHAKAHLFCGHVHRTISGQASGVPFTMFKSTCHQAPLDLIAADSTLSNAEPAAYGLLL
LSKGGVIAHSEDVGLNFPPISGSDALPKH
>A0A090FF37|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mesorhizobium plurifarium|TrEMBL
MKIIQVTDVHLGRRREIRYGANLNERLDRCIDHINQRHSDATLCIFTGDLTDDGEAESYA
DLKAALSRLTVPFRLLPGNHDRRANLVAAFPENGTDGNGFVQSVFDAPEGRLVFLDSLAE
GRVTGELCDDRLGWLDARLAEAAGKAAYIFLHHPPVELGLTLLDPLGLEQPQRLIDVLTR
HGNVRYIFFGHVHRDIAGTVAGIPFSVQRGLHARFMLDLVGDEMVEQAPPAYSIILIDGA
RVVIHSHDFLEQWPLWSPATGQRVR
>A0A5P9IY24|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudoalteromonas sp. THAF3|TrEMBL
MAWFDPPYFCPASTELNFAHFTDAHLFAQPQEQYFGVRTGQHLQQTLAAMAAEAFDFVVF
GGDLTQDHSPESYQLFAELVANSALQCPVFWVPGNHDELSQLNAMTEGQIRPEKRIEHAC
GQVLLINSKGDTPAGWVAENHLAELGDAIDTAASQQVFITHHHPLPIHGYLDKHILENGD
ALLQCIETRSRSATVLHGHTHHDYHHDYQGVEVFGTPATSVQFVKNAASWQQENLGPGYR
RVRLVANKAPITEVKWLAN
>A0A267BBZ7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas fragi|TrEMBL
MPNVSTLTTEDPVLLVQLSDSHLFAEADGSLLGLKTAQSLQQVIDLVQAEQPHIDGLLAT
GDLTQDGSVEAYQRFRTLTAPLAPFGRWIPGNHDQVAQMREAAVQSRLLEPVVDIGNWRI
TLLNSAVPHSTPGYLEDDQLQLLAQSLSEAPDRHHLVCLHHHPVSVGCPWLEPIGLRNAK
EFWSVMDRYPQARAVLWGHVHQAFDQQRNDVRLLATPSTCIQFAVGSPDFKVSGEAPGYR
WLRLQPDGTLQTGVSRLADFTFEPDYSANNY
>A0A447JCC3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salmonella enterica subsp. enterica serovar Daytona|TrEMBL
MRNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLLASPSTCVQFKPHCANFTLDTI
APGWRTLELRANGVLETEVHRLQDTRFRPDTASEGY
>A0A125YN43|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii (strain ATCC 50861 / VEG)|TrEMBL
MHISCVKGRIVARQIDNVFTVIFAIEVLGKFVSYGLEYLQDPIESFDTIVVLTSFTLLVL
GFYVSGIGLLRILRLLSALALLHKYPDSKEKRPELSAGNSSKLEKASSIVEGLLTNVHIP
KYFKTELEWVWDSILANKVYDSHVVENEEEEEDQATETIIAGSDASRKTQAAVRASRAQS
RASKLPHGSSSMVVGTTNGRMSGQILETLREPDPRMMDAALYKSETRNLDPLTATVGGMK
NSPSMFAKGSKSSNMMGSSASKSFRTERNKKAIDIISVLYQASQITGAEQEQVNEAMRPF
DEWQWDALHAGDVCDMNLLPVVFVRAIATFPTIMTKFNFDLDRLFDFLKVVQTSFQKNVK
FHCAAHTADMIQAMHYFLTIGKLGALLSEYDVFLCHFCALVCHFGHPGVTNTFLVKSRHP
RAIRYDDESVNENYVASAISCLVAREEYNFFGDKLPLWQVFRLHMIDILLNFDISKSAHQ
VAMFRTKVSIKFTASTPADKQLLLTILLRAADYSFTCRQLALYSKWKDRMIDEFFAMGDT
EKQLALTVSPFCDRELTNVDKCHVAFAEVAVKPLMTVLVLGLAPHLQKDVLDTLEANQKN
LMQKLDKSD
>A0A565A4S8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Plasmodium vivax|TrEMBL
MNMQCNKTNPTCEISSVKDFLRNICLDQEDKIVQNLELRNVKTVYDFLRHVSYLTVTSCT
GMNNDENVDITSQSNVKFASAHESIFQNGVSVNGKLTQQLAQQLAQHNGDGGNPGEAQLC
NGHTSAGREKGDRCNGVQRNGPQGGGKLANGVSSNGVSSNGMDGSAGRDDPAAHSESTQA
CKEIAAMRDYYEQAREKRSGAEKKGEYVYFDMYIKSEVIKTLPTTDRDKERLINYIYKVM
DVNDLLMMCIHFGLPHLWPKFEQSNIRNVELFKRIIIEGRKFERVKNEMGISFSEFVQIV
NFTLSVKKKRIFCNNIFSQFDPCDCKNKKKHTKTICDKIHQFIEFDNWTFKNIIDNPFFQ
RLRNLSQLGVCQFVYPGATHTRFEHSLGVGYLSAKYFAHLCNRYNLSPYSGELNKMLRCV
QIAGLCHDLGHGPFSHTFESFFMNYKKEETDHKWNHASMSLKIVEHVIENLIDQDDVLDS
TDIKIIKKLIKGREHHKSVCGVDPVDSLIEASYDIICNNRNGLDADKFDYLQRDATIAPP
NGTLPSLNCNRIISQSSVINGHITYNVKEIHPVWTVYMNRFSLFKQVYTHRKVRVMELML
CDGFRLADDIFKWSESLHDLDAFLDLTDSSIIYDIKKRANKHKYDEKVQKSLNLINSVIH
DRNSNHAYKYISEINLSEPQLIKYLKDIANEERIARYAHGLSPDDIIIDWNYLNYGMGAN
DPLDSVYFYSSDNEDEAFIAHKEYRGTHPRYFEECNVRLYCKNKMVAHLAKDAHNKFLSD
VFSESSPLYKKKIVK
>A0A5E5PYA3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Gammaproteobacteria bacterium|TrEMBL
MKHFIQISDCHIDDNAQTMEVDSHINLAKVVDKIVTLQSDALLISGDLTHNGTPHSYKKL
KEILTPIETDIFVIAGNHDDSNNLASEFGACLFDCITLGAWDIINIDSVQLGKTSGFVTK
NTLTTLDKQLQHSNAKYNLIVLHHPIVPMNSAWDDALSLENPQDLFAVLDKHPKIQAVLF
GHAHESAEFDKNGLKIIACPSTATQFNDERRIGFNYYTLFDDGRLDYETQWINS
>A0A4W6DPT3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lates calcarifer|TrEMBL
LGSKLKYFSEVQRKTLLDCAVCVCVVRLKGVLEQMDRGVVDLQELRRNLELAAAMLDAVY
TDETRRLLDTEDELSDLQAESVPSEVRDWLACTFSRKMGVAKRRPEEKPRFRSIVHAVQA
GIFVERMYRRTSNMAGLTYPPTALTALKEVDQWSFDVFSFHEATGDHALKFLVYDLLTRY
DLINRFRIPVQALVQFVEALENGYSKHRNPYHNLIHAADVTQTAHFLMLHTGLMHWLSEL
EILAMVFAAAIHDFEHTGTTNNFHIHTRSEVAILYNDRSVLENHHVSAAYRLMAEEDMNI
LVNLNKDDWRELRSLVIEMVMSTDMSCHFQQIKTMRNALTQTHGIDKVKVLSLMLHAADI
SHPAKAWPLHYRWTHSLMEEFFRQVLCCSGIHEAVFRAVILRLTSSTLLTGEDVYDMQI
>A0A086K0T9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii FOU|TrEMBL
MHISCVKGRIVARQIDNVFTVIFAIEVLGKFVSYGLEYLQDPIESFDTIVVLTSFTLLVL
GFYVSGIGLLRILRLLSALALLHKYPDSKEKRPELSAGNSSKLEKASSIVEGLLTNVHIP
KYFKTELEWVWDSILANKVYDSHVVENEEEEEDQATETIIAGSDASRKTQAAVRASRAQS
RASKLPHGSSSMVVGTTNGRISGQILETLREPDPRMMDAALYKSETRNLDPLTATVGGMK
NSPSMFAKGSKSSNMMGSSASKSFRTERNKKAIDIISVLYQASQITGAEQEQVNEAMRPF
DEWQWDALHAGDVCDMNLLPVVFVRAIATFPTIMTKFNFDLDRLFDFLKVVQTSFQKNVK
FHCAAHTADMIQAMHYFLTIGKLGALLSEYDVFLCHFCALVCHFGHPGVTNTFLVKSRHP
RAIRYDDESVNENYVASAISCLVAREEYNFFGDKLPLWQVFRLHMIDILLNFDISKSAHQ
VAMFRTKVSIKFTASTPADKQLLLTILLRAADYSFTCRQLALYSKWKDRMIDEFFAMGDT
EKQLALTVSPFCDRELTNVDKCHVAFAEVAVKPLMTVLVLGLAPHLQKDVLDTLEANQKN
LMQKLDKSD
>A0A839SD42|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mucilaginibacter gotjawali|TrEMBL
MPLGVKGGIDESNLSAYMVGAGGTDNYICLDAGTLHYGIDKAIAKKVFSIPAEQVLRRYI
KGYFISHAHLDHISGLIINSPDDTAKNIYALANCIETIKTHYFSWESWANFANEGDKPAL
NKYHYQVLKPDSITAIQNTTMTVQAFPLSHSNLTSAAFLIRSNDAYLLYLGDTGPDEVEK
SNNLQSLWQAIAPLVKSKKLKGIMIETSFPDEQPDKTLFGHLTPRWLMKEMVDLASLTGN
QALNGFNLIITHVKPPQDNIEKIKVELKAENSFKINLIFPEQGAAIEL
>A0A1Q8LQJ9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudonocardia sp. Ae717_Ps2|TrEMBL
MTTVVQLSDLHLGRPDPEGRAARAVAGVRALDPAPDVVVVTGDLADHGDPAAYAGAAALL
AGLDALHVPGNHDDRTAMAAAVGPVGDRLHRTGGCTVALLDTLVPGAPHGALSEGAVALL
TEAVRDPAPLLVALHHPPVALGHPVLDGMRLRDPGPLEMLLAARSDPTLVVCGHVHTPLA
TTFAGHPLVVAPSVAPALRWPDVPGAGGSDPVPAPGGVLHVLGDGPPRSRFLNWPV
>A0A142WWH4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Planctomyces sp. SH-PL14|TrEMBL
MLNRREFLTTLSAVPLLTTIPALAQDAAKKPLRFGLITDVHQDIIPDASARLGAFVDAMT
RAEVDFIAQLGDFCIPKEANRGFYEVWERFQGPKYHVLGNHDMDGGFTREQTVRYYGMPH
RYYAFQQGGVKFIVLDGNDPGGTSQGYKRFVGQEQAEWLRKELSADARPVVILIHQPLDG
PSGVDNFAEIGRILKGEGGARPNVLAVFSGHLHQDYHRPIDGVHHIQVNSASYYWMGAKY
NHRSYGEAAHEKSPYLQSTCPYEGPLWAVVTLDLAKGALTVEGMKTAWLGGSPWDVGATP
QSHDAGIVRPEVSPRSIVLA
>A0A6J4MDU2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Nocardioidaceae bacterium|TrEMBL
MVLLAHISDLHIDGGGRAAARVERVLDFLNGMARPVDAVLATGDLTDNGLESEYDELGRL
LGPEHGLLLCPGNHDVRGPYRRVLLGEPASDEPINRVHDLPEVRVVMCDSSVPGRDDGHL
ADETLGWLDEVLGATPATTPVLLALHHPPVLLHSPFIDEIRQYGAERLASLLDRHDQVVA
VLTGHAHTPAVSRFAGRPLLVAPAVASTLRLPWENDMDLDYEMPPALAFHVLDDAGRLTT
HFRLVA
>A0A1V5NC26|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Planctomycetes bacterium ADurb.Bin401|TrEMBL
MEKNITRRQLLGGSLAAVAGLAAGSKFTTSQAHAGILNKKAKRSIRFAHMTDIHLEPKRN
APQGLTAALRHVHTQKDKPDMIITGGDNVMDMLGCDANWADTQINLLKEIFVKECKLPVK
YCIGNHDTWGWDKNSNTNRDDELWGKERFVKAMGLENRYYSFDAGNWRIFILDSTHIDER
DAYTAKFDDEQFNWLADQLKKSQNKHVCLINHIPILSAAVILDGDNVKQGRYTLPDEWMH
LDSRKLVDLFWENKQVKLCVSGHLHLQERLDYNDVTYICDGAVCGAWWGGAFQQCQEGYG
LFDLYEDGSFGYQYIDYNWEVEKA
>A0A170WPY9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Triatoma infestans|TrEMBL
MMFAIITATQWWKIFGDIECLALVIACLCHDLDHRGTNNSFQIKASSPLAQLYSTSTMEH
HHFDQCLMILNSPGNQILANLSPDEYSRVIKVLEEAILS
>A0A0S4WZR7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ralstonia solanacearum|TrEMBL
MRKNITVVQITDLHLLADPDGQLHGYRTYPVLSDTIDAILNYDVKPDMCFVTGDISQDES
EASYDLARSELERLGIPVFWIPGNHDDRDKAAAAFGKSESIRRLMKLPTADWDFIYLDTC
RRGADEGYLNDADFDRFVSEVRASVGQGKHVAVVMHHHPVPTQTPLMDTYILQESERLLT
VFDDHPQVKLVICGHVHGDYQLQYGNQAIEMCPATCFQWEKGASIIKTEDWRGFRMFEFS
QSGYRSAFVPA
>A0A5C6DD61|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Novipirellula artificiosorum|TrEMBL
MNSNHQRLGRRSVLQNGTLIMATAAVAPSTLIAEEIDSTLKIGLLTDLHFADKPPAGTRH
YRETLNKLEEAALQFEQDKPAFVVELGDLIDAADSVETELRYLSTIDRPFSAIARDRHYV
LGNHCVDTLRKEEFLGSVGQEKSYYSFDRGGVHFVVLDSCFRSDGQPYGRKNSVWTDANV
PAAELEWLEADLKSACNRVIVFAHQRLDVTSHHGVKNGAEVRRVLEASNKVLAVFQGHSH
QNDVKDIGGIHYCTLVAMVEGSGADNNGYSTLSLKANGTISVQGFRQQATYGWES
>A0A128F689|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Grimontia celer|TrEMBL
MTRILQLTDTHVVCPPNKVSGVLDTLTLFEDAITKIEQDLEKLGHVDAIIVTGDITDHGD
VESYDAFNSVIRRLGIPYFVIPGNHDLRSSMHHCFENLTPATSDEINWVKHFPDLDIIGL
DTVIPGQGGGRLSPTALAFLEHALTRHPDKPALIAMHHPPFASGIQFMDAIGLEGADEMA
EILEKSPRDVRVICGHLHNSIVATIGGATVLSSPATASSFLTDHRSDAPVGFTQDPGGYM
LHEWNKGFRSTYLPLASSGQLYPF
>A0A812D5Z2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Sepia pharaonis|TrEMBL
MHSEQYFLIRKSYINHYYKIFINPFFSLSSIYLSIYLSIYLSIYLSIYLSISSVQCTEEE
YQQFCDKDVRKELTILSDVNFNSWSLDSTQKVTYVLHMGWDIFKNVRLDMNNFIRFVLTV
RKNYRNVPYHNWTHAFSVAHSIHNFYISNLISLSLSLSLSLSLSLSL
>A0A1P8WHG9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Fuerstiella marisgermanici|TrEMBL
MPVHFASLPRRTFLQTSLGVGASLLTFGNASGDESQDQPEHVALLSDPHIDADATKVVRG
SVMSANLLNVIADILAQPKKPVQAFIDGDCAFNVGLPADYQTLAALLAPLPAARIPLHMA
MGNHDNRVVFRKQFADNENESTAVDGKHVSLIETKHANWFLTDTLQKVNNVTGELGAEQL
SWLTAALKSRSDKPAIVVGHHNPQFDVPDGGRVTGLQDSNELFDLLESQPHVKAYVFGHT
HSWSVKQRDSGLHLINLPPIGYTFNEKSPLGWVDVALNATGMQLSLRSIDSDHPQHMETH
KLTW
>A0A0H3FFF2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rahnella sp. (strain Y9602)|TrEMBL
MKKYLLAMMLACWAGQANAGFDVVALGVNGGVEEGNLTSYLIRSDDQKLYLGLDAGSVLP
GIRKALEKGSFPQVTAENAAPLTPQGAVFRNLIGGYFISHGHLDHLAGLIISSPEDSKKP
IYGTADTIGTLRQHYFNGRVWPNFTDSGSGLRIGTYRLNQQRPAQRFSLGLTGLDGSIYP
LSHGGTPSSMILVSRNNQSFAFFGDTGPDEVEKSKNLDTVWRMLGDEVKAQRLKGLIIET
SYPDGVPDSKLFGHLTPDWLLKELGTLQQYAGGEGSLKGLTVIISHVKPSLKAGADPEQA
IMAQLEKGNNLGVNFVRMAQGDKLEIK
>A0A1R4I2B3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Halomonas sp. JB380|TrEMBL
MRLVQITDAHLHADVTTRSRAGVPWLHFQRVLAAAAAERPDVIVVTGDISQDETAASYTL
AKEALAGLPCPWFWLPGNHDQVEFMCAEHPLLDEVDLQQWRLLLLNTQVPGQPFGELGSE
QLMALTTRLEEDDRPTLIAMHHPPVDVGANWMDAIGLQDREAFWQVLSAYPQVKVVLFGH
AHQAYAQHIEAAAGSVSVYGCPAMSDQFMPGADVFTIDEASRPGYRVVDLNGEQWDTWVE
RVDV
>A0A378ZWA3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pannonibacter phragmitetus|TrEMBL
MKIIQLTDTHLMPPGAVVNGVDPERQLRLAVDDILARHGDTDLMVITGDLCNHGDPEAYA
LLRDILAPVSFEVRLLIGNHDRRPEFRDAFPEHPVDGQGFVQSFKDTGHGRLLFLDTHEA
GMIGGLYGADRMVFLDEALAGAGDVPVTVFIHHPPFDCGIGHFDNIGLHDDGALMQRLGA
HPGGVRHIVFGHIHIPMSGTAANGIAYSSGQATGHRFITDLADPCPWWTGGNPTYRILLL
DDHGLRAYTAETSQVATSRAARCEGP
>A0A1S8NIX3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium saccharobutylicum|TrEMBL
MALYTISDLHLGFNVEKPMDIFGDKWKNHSEKIRENWINKVTDEDMVLIAGDISWSLKEQ
DSKYDLDWINELPGKKIISKGNHDYWWGSISKLNAMYENTKFLQNNFYVYEDYAICGTRG
WMCPGGDKYTTKDEKIYSREQIRLRLSLEAAKKKGFEKIIVMLHYPPTNEKFEESEFTKI
IKEYAVEKVIYGHLHGPVLLGNVLNGYLDGIEYILSSADYIDFNPRRIL
>A0A6N2SVZ6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Campylobacter ureolyticus|TrEMBL
MKIYHLSHTDLDGYGAQFVTKHYFKDILFFNSNYGREIEAKFEEILNLIENSAKVNENNE
KIYEKSIVLITDLNLSLQQCEKFENALKDKNSTIFLLDHHQTGLECSKKFPWYLMDSSRC
ATLITYDFFSKLYGKDDRLFKFVNVVNAVDIWLKDNHWFEMGKVCMGVVSGAKEINKIMF
DENSREYIFYLLDKSQTFFDQDNGHIALDEALHKIKKEYFKKQNDDTLSNLISKFIVEKL
SADREKFEISYLDKKGILTYNIGNTSIIGNDFLVQNPDIDFFIDVTSKKTLSFRANGNAD
VSQMAKDLVGGGGHVNASGGFYAGFKDGYNYQSIKDQITDLISKKTSLA
>A0A1S8L818|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium felsineum DSM 794|TrEMBL
MKKLKLIITGIIIVIILAVIAIYIYIPKTISKVKVKAKPKAQLTFAVLGDVHNRTDNLQR
AINDLYTIDQDIDALILNGDTVDQGIESQYDSVKKTLKRNKDILPKTIIENIGNHEFFDY
NIGTNSKAQVKTFINRYLGFSQEKKVYHDKWIKGYHFISLGSEDGKSKTTNSTEASISNE
QLIWLKEKLAQNYTKGKPVFVFLHQNLKPFWNWQGVKQSEEINEILSKYPEVVLFTSHTH
ADLDKNSVLENQPFTMVHAAALQYTLIPEINSRGVITDITKKQYIKGLYIEVNGDKVIIK
GRDIKEKQWIFTKAITK
>A0A1X7AG55|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Parendozoicomonas haliclonae|TrEMBL
MLHRPSTLIQISDSHLFANDERSLLGIKTRQSFADVIKMIRAQESEIDHIVVTGDISQDD
SMESYHYCHKVLSDMHVPFSWLKGNHDDMSTAASVMYQANFPDIQEVGNWLILMVDTHVS
GEIHGMISEEAMARLEEQLVTHQDRPLLVAMHHHPIPVHSRWMDDICLSNREAVMTLLKG
YPQVQAVIHGHTHQERDQVYNGIRVLGIPSTCVQFAPGSEDFAVDNQQPGYRRLRLFPDG
RIETSVHRLPDNTWLPDRSQAGY
>A0A218UF94|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lonchura striata domestica|TrEMBL
MGMMLKRTEEKPRFRSIVHAVQAGIFVERLSVIKLLYSTYYLPRMYRRTSNMVGLSYPPA
VIEVLKNVDKWSFDVFALNDASGDHALKFIFYELLTRYDLINHFKIPISALVSFVEALEV
GYSKHKNPYHNLMHAADVSQTVHYLLFKTGTVHWLTELEIFAMIFAAAIHDYEHTGTTNN
FHIQTRSDSAILYNDRSVLENHHVSAAYRLLQDDEEMNILSNLSKDDWR
>A0A183GGV8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Heligmosomoides polygyrus|TrEMBL
LVRKADSVCNERQFDNTAAIDTVEKKMMLVGDTFGFYQLVLRKHSCRLRYILHQLNSGQL
PLEDLKRNIEYAALVLETAYMDETRRSCDSPTHDPADKLDMYSTILSATRSAHEAPSRER
VREWLAATFTRQNAGKKREKPKFKSVANAIRTGIFFDKLFRKQQSVQCPIPPEIAELLRE
VNSWSFNPFQLNEVSEGHALKYVGFELFNRYGFMDRFKIPLVALENYLHALEQGYSKHNN
PYHNVVHAADVTQSSHFMLSQTGLANSLGDLELLAVLFGALIHDYEHTGHTNNFHIQSGY
VAVCRRLCSCALRDLSSYVMKVVLCHIALTTAFEESKN
>A0A379UW94|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Salmonella enterica I|TrEMBL
MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYEYDLIV
ATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQEAGISRLSAC
>A5FKL1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / JCM 8514 / NBRC 14942 / NCIMB 11054 / UW101)|TrEMBL
MTHFSRLLLCFILVSFNSFSQKEHKASFQVVPLGIKGGIDEKNLSAYLLAPSNSKDFICL
DAGTINAGIEKAIDNKVFKVSTSEVLKKYIKGYLISHAHLDHVSGLIINSPADSSKTVYA
TEKCMEMMENHYFNDQTWANFGDKGPGFPLKKYHFQTLNLSEETPLSNTTMSVKAFPLSH
VNPFESTAFLIKNDNDYALYLGDTGPDSVEKSDKLKTLWTAVAPLVQSRQLKGIFIEVSF
PNEQPDKFLFGHLTPNHLMTELHVLEELAGKGSLNNFKIIITHLKPPAKSIAKIKEQLKN
QNNLGLKIIYPEQGKKIEL
>A0A890DL54|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli|TrEMBL
MDVFRHAGTPVGILGFAIIMAAVSAFVNDKFIEQVNKLIGI
>A0A1Z5JJK4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Fistulifera solaris|TrEMBL
MIEDSDHSWSVDCGESSDGDIRSHGTDTLEKERAEEAAVAELTRRETRGVQMWRAFTLLT
LVAVSVAVSTITYRLLQNQDVEEFQDSYVYFASAIQNAIETHIEDVFSAGELVSVQVTKA
SIEKNESFPFVTLDLFEIIGSQARKLSGVDEIIWSPMVAAEDYDAWTIYSTENIGWYNAS
IGLYVPESEDSEDLGNEEEDEGEEEEEDDRKLEGYDFSDTTYSISSPGEDQNAGPGPWAP
AWQVSPPPPGSHIINIDMYAYGTKMVEEAVDELRMGLMTEVIATPGAENVPPRCVVVEPV
FEHLLDDLTAPIVGHIYSTFSWDSYLVGLLPEGVSGINVFLMNTCGQAFTYAISGKSVEF
VGNGDMHDARYNHMEIVIPFYDDEADDQGDIDQIEGHCATTMLAFAFAFMITAFIMFDTF
VVRRNRKLLIAMTRTNAIVSSLFPSTVRDRIFAQAKHENEEKKALNEKSRLKTFLSDGND
RDNEMGEGNDEYMYKTKPIADLFPETTILFAEPTQVFILLETIYKAMDDIAKARRVFKVE
TVGDCYVAVTGLPDPRKDHAVAMCRFAIDCVQKMDVLTRKLEVILGPDTTDLKMRVGLHS
GPVTAGVLRGERSRFQLFGDTMNTASRMESNGLPGKIHISQETARLLIAAGKEHWVIPRE
EKIIAKGKGELQTYSLVTTKASNHTQSETASSETSGEVGGSNMLAGAAYDIVIPEIDEKT
DRLVKWNVEVLAALLKKVIARRKDVVNTIESAPKTNASKFTSTPLEEVQEIIHLPVFNRG
NGADTTEEDLGDVVIEQLREYVSAIASMYRNNPFHNFEHASHVTMSVVKLLSRIVAPDVD
AVNNDLESTLHDYTYGITSDPLTQFACVLSALIHDVDHPGVPNTQLAVENPQLAKFYSSK
SIAEQNSVDLSWELLQDSTFNDLRLAICPTEHDRIRFRRLVVNSVMATDIMDKDLKALRN
KRWEKAFSGKNQEESMKDAVDRKATIVIEHLIQASDVSHTMQHWHIYTKWNQRLFEEMYS
AYIQGRSTTDPSENWYKGEIGFFDFYIIPLAKKLRECGVFGVSSDEYLNYAEKNRQEWEA
RGREVVAGMVERRTRSLARSWTN
>A0A378JM27|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Legionella busanensis|TrEMBL
MNNRFLTKTNLKLLQITDLHLFASNDKRIFGIDSNNRFKQVITHIKQHELHDTDAIILTG
DLSQDETRESYQHILMAFKEFKIPVYWIPGNHDNLLLMQSVFASSSILQYKRVLNCKYWH
FIFLNTAIPSQGVGYLNEEELFIITEEIKKLEEPKKIALIMHHHPAYINTPLMDQYGLKN
QSQFWQKLINSPVQLIICGHVHGHYSFEYQNITIECAPATCFQIKKGAIDLKIENLIGYK
CHIFKDKTYQSVPVLWAAN
>A0A1F2PKI3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acetobacterium wieringae|TrEMBL
MGHKRSKNLNSRLAKQLKDIEQQIIPVTVPVTETETEIHSEKAVYTFYLDPVVATAPQVE
AGEIHRLAREGYGGWIAEDPKEPERRDDLMPEGYLLPAGNEPEQLLHFFAITDIHITDGE
FPAHGIYSKFGGGIVSVYSEMMHYTTHILDGAIHSINAIHHQNPLDFGLSMGDNTNNAMY
NELRWSIDIFDGKEINLDFGVSPNPRVGPRKPFYDEFAAVGLNPQIPWYQVIGNHDHSWP
DKPLLPVSDDPARRFLSRAEWMKEFFITETKPSGHGFSLENSQSGFACYSFEPRETKQIK
VIVLDNTQRDDDQNVKGYAHGSLDRERFDWLGQELEAGQQAGQLMIIAAHIPIGVEYQEP
LTRPFMSWSTLSPVSEQELLKKLQSYPNLILWVAGHRHRNTVTPIKSPDPAQPEYGFWVV
ETASLRDFPQNFRTFEILKNSDGTLSIVSRNINPTIREGSFASIARSYAVAAQQLFNGRT
ELLPSGSYNGELLVKTKA
>A0A517N4W4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rubripirellula lacrimiformis|TrEMBL
MPIHLTSLRRRSFLQTSLGAGASLLTFGPALGDQTYDATEHVALLSDTHVDADATKVVRG
SVMSANLVNVIEDVLDQTQKPTIALIDGDCAFNVGLPADYKTLASMLTAFPAADIPLHMT
MGNHDDRVAFHKQFASHGKENAAVDGKHVSMVETKFANWFLIDTLQQVNHVTGEMGAQQI
RWLRAALKANAGKPAIVVGHHNPQFNVPDGGRVTGLQDSVALFDLLESQPHVKAYVFGHT
HSYSVKQRPSGLHLINLPPIGYAFSETSPIGWVDASLSATGMQLTLRCIDNGHDQHLATE
TVAW
>A0A1S8TLU1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium sp. BL-8|TrEMBL
MNRVKFAVFTDLHYDHIHDGCKRIDDFITNIKDADIDFVIQLGDFCIPKEENQFLLNKMS
SIGKPIYHIIGNHDSDSFPREKVMDFLKMNNSYYSFKNKEIKFIVLDTCFIKTNSGYKPY
SRKNYNKTNDIYPVLPAHELKWLESQLNDDNKYYVIFSHHSFENEFAKRGVYNRCEIRNL
IDAVNNKDKKVLLCINEHDHGDSLKKIGQTYYFGLNSMSYIWFGPEHEHFCYSKEIHKQY
PFLKDIVLYKDGLYAVVTITENGSINIEGMKGDYQNISPKELGIENVWNGRYLSPIISSL
KVD
>A0A7W6KDP9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pedobacter zeae|TrEMBL
MFKRILPVIILFFISTCVLWAQETNKGFTIIPLGVKGGDDESNLSSYMIAPIGSEKYVCL
DAGTINAGIQKAIDMKSLKGISEEVQRRQIKGYLISHGHLDHLAGLIINSPADTAKNIYG
LPSVLNILKDKYFTWDAWANFANEGEKPQLKKYTYFPLVENNNYQLEGTEMKVKAFELSH
GNPYKSTAFLINHDDIYILYLGDTGADEIEKSDKLASLWRSIAPLITAGQLKAIFLEVSF
PDEQPDKQLFGHLTPKLFFNELSKLEALTTDKAFKKVSFIVTHIKPPRSTAEKVKQQLIS
GNIKNLKLIFPEQGQSLTIN
>A0A1W1D8U7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MIKLIQISDCHIDDQVMTMGVNTQENLKKVVKKLSDYEFDVMLISGDLTHNGTPSSYARI
KEILAPINTPIHVIGGNHDNLIQLNTIFKDNILNSTKLGNWQIIGIDSVQLNKASGLLTK
EALNDLDQKLSDSNSEYIIVVLHHPIVSMNSSWDDNLSLENPGDLLQVLNKHSKIRCVVF
GHAHESASFNHEPFAIVSCPSTALQYNKESRIGFNEFTLYDNGQINWTTQWI
>A0A7H4NC87|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella michiganensis|TrEMBL
MIFNRQCTARCRNPASLPLKRVLLGDHWQVLLMDSQVFGVPHGELSDFQLEWLEQKLTEV
PQRYTLLLLHHHPMPSGCSWLDQHSLRNAGALDCALAAFPRVKHLLCGHIHQELDLDWNG
RRMMATPSTCVQFKPHCANFTLDTVSPGWRWLELHPDGTLTTEVCRLEGVKFHPDIASEG
Y
>A0A0P1HMD8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Phaeobacter sp. CECT 5382|TrEMBL
MKFIHISDIHLTIPGEEMGGLDPHARFACALKDIADNHADAERIIITGDLTHWGEVEAYQ
ALQTAIQDLPCPVRLMIGNHDHRDTFRQVFPKHPVDANGFVNHAETIEGCRFIYLDSTGD
KTHAGHFCAARLDWLEAELNTAPHARIFMHHNPMLLGLPAVDQIGLVAQDRPGFHALIDR
FSDRIDFIHFGHVHAHISGRFKGIPFASVPSTGNQSIPDLQEEVFLKGAGMDPGYFVVLA
QGRDTIIHQVPFSWDGQVNLSGVSWEDWRKPSLAGA
>A0A161WFK4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium magnum DSM 2767|TrEMBL
MKKIKIIIITIIVILLSVMSAIYIYKPRPITKATATVKSNADLAFAVLGDVHGNIDSFQR
SINDLYRVNPDIDALVLNGDTVDQGIEEQYDSVKKALSENKYLLPETIIKNIGNHEFFNY
DAGTNSSQQVQVFINRYLEFAGEEKVYHDTWVKGYHFISLGSEDGNSKTLDSIKAFISKE
QQNWFKEKLTENYQKGKPIFVFLHQPLGFKYGNKTYVGVEQSDQIKEILSKYPEVILFSS
HTHRDLDENSIVLNSPFTMINTGAVGYTLIPDESSQRGMRRESSYIKGLYIEVNGNKVIV
KGRNIKEEQWIFTKEFLKE
>A0A2N7RLM5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Janthinobacterium sp. AD80|TrEMBL
MRLLILSDLHLEVWGDDTPAIDLAASRPDVVILAGDIDTGNNAIAWAARTFGALPVLYVH
GNHEGYGHQLEHMQDAVREACASANAHGASIRLLDGDAVELNGVRFLGATLWTDFLLFGA
ERQEEALNAAQSYMPDYQRISTGGDTPRLLCAADTAQLHAQHKAWLQQQLAQPFNGRTVV
ITHMAPSMLSVEEQYATNLGSPAFASQLDAMVAQADLWVHGHMHASLDYRIQDCRVVCNP
CGYKRPDGTPENEAFDTGFIVELANVA
>G0QJ48|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ichthyophthirius multifiliis (strain G5)|TrEMBL
MALNNNPFDQLQEDNENCGFQNKIYENEDLFELKAFDLKKFPDEKIKIFKSSSKQIIVVT
ITNRIFRWRYELDDEFIEYEIPEKKDEGNIISTIAGVANLAKDIGKKMLFMNTNKKNTYI
EQFFLDVKGYHCIFCSDQGLNFYFGYNQQKIKVLKNIKGDEFTIRSAAFDETCTETNTKN
MLLGTTDGVLYIYKIEYQKNTNELIESNPDRILQIPENRPILQIVYFLVQIQQQKQQTKT
GLVVLSTSQSLYTFTGTSDLSLLLSKYKQVELEKLEKVTFNPSESSLLDVCYEIDNKGNR
SPQSIIWTNGYRLNYYIIPKNQNQFNEKFLSQPSYYRYAKQTDQTEQEKQLKVEQMPIDI
CLTLYHYFILHQDSLTILSRINEKVVQYFDLKSIGKILGMSFDIENQQIWIYSNRKIQKL
IIQNEDKVLLLKIKKNIFMCIYILKKDAWKLYLEKKEYKQAYEISSKNSLEVTEYLSGLY
ADELFEKRNYVLAAQQYFQTERSFEQITLKFIQGYQNTNEVELNEGLETYLELWLKKLKN
EENLKAQKCILLIWLIEIKVQKLNYLEAKYQSKQNQLKKLKEQDELWDRTYNQFLQLNDK
FKKTETEFKKLLSDNLNDLEENIVYQIMQSHGRLKDCLEFAQKNSYEMIILHHINEEQYD
QALKYLFQIKEKHINEVLYKYCHIFMRYRTEQTIQLLQRYTKYKPQKLIGGLMSIHMEKR
DQGINYIQHLLNNGCKDKVIHNILILFLSDPSKKNKLKEHLYQQEKILQEKEQVNFDLEF
ALRLFRTNKLYSPQIQIYGMMGMYSEAVELALKTNHIQLAKQYADKPINIDCRKKLWLNI
AIHLLGKGGNNIDEVIQLTKDTDLLKIEDLLMHFNENIKIENFKKEICESLQEYNKEIEQ
LQSDMESYSSNADQLKNELRIIKNRYIEIESNHTCEECFKNLFNEAFYVFPCMHAFHKDC
LLSKVKESCTDQNKIKQIEKLNKKIEQLQAKMNRVEQRKRDSIDSGFFNFVNIFTGRLSE
DDQQQAPVMSPEEERQLEQSRNQFDTILANECIYCGPSIVESIFQPFEQDDDLKESWKI
>A0A0R3RL25|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Elaeophora elaphi|TrEMBL
MALFTAAAMHDYDHPGRTNAFLVASEDKKAILYNDRSVLENHHAAESWRLLSKAENCFIE
TLDAAETKRFRYLVLEYILATDLKLHFDIIMQFNEKAPDMDLNNESDRVIISQMLIKFAD
INSPSKPYPLHRQWTDRICEEFYGQGDEEKRRGMAVSPYMDRDDPAVAKLQDSFISHIVS
PLAVALNEAGLLPVLPGLEEPELIINLKHNHQKWLSELEEQLAFTKAVESGTTALATNVP
SQSTSLSLKTSNHFFPIIQLLLTISHIE
>A0A0M7AFG2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseibium alexandrii|TrEMBL
MKLLQLTDIHLTKPGDTIAGRDPNENFRKALGHAVTHHPDAEAIFITGDLSDWGDKDDYL
RLKAEIAECPLPIHLCIGNHDERDVFLSVFPEGADENGFVQAIVPLSEGTAILLDTWGPD
THAGFYCSKRQDWLDRELSKATGPVFLFMHHNPVPIGIAPMDKIMLQDADGFGQVVARHA
AKIRHIFHGHCHLPLAGSLHDIPFSAPRGTNHAGWPDFANKGNLAGSDLPESYAVVLAEE
TSTMIHMIEYGYEGTVRREGSPDYADWDRLTMVR
>A0A517ZRG0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Symmachiella dynata|TrEMBL
MTTQILQLSDFHLLKNRADELRGVPTADCLMDLLTLVRTNYSAADLFVFTGDIAAYGDVE
AYQQTRELFADLLPRCVMIPGNHDDSDLMREVLPERIAGSSGPVTFACDVAGWRMIGLDS
HVAGAVHGELSGEQIAWLADELSQHADQPTLLFMHHPPISVASVWLDRIMLRNANELAEV
LHAAPQVRGIFCGHVHQEFSGMLSAIPVHTTPATAIQFSPHTEELEFDHLPPGFRVIELD
GDAMHTHIVRLPELKYPAT
>A0A162FK18|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Methanobrevibacter oralis|TrEMBL
MTLIVHISDLHISKVNFDEDLFMMAVDEINHLSPEMIILTGDITDNGYYKEYLQASKLLP
FFEAPLFAVPGNHDARNLGYRTFEELIGERSWKLTKDDNFTVIGIDSSSPDENGGQIGIP
QHMWLEHQLDDCVINNNFSVVALHHHVVSIPDTGRERNVLSDAGEVLKTLTTHEVDLVLS
GHKHVPNIWKINNTIIANAGSLCSEKLRGKNQNSYNVYNISDKSIEIYLHNVGGERLLFD
EFLRNSI
>A0A162FL61|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Methanobrevibacter oralis|TrEMBL
MKFLAISDVHGEDNENLITYLKNNDIDLVLITGDITNFGPLDFVDEFISKILGCDCDVMA
VPGNCDPEGICNAINESGAFCLHKNIVAYGDAVLFGYGGSNPTPFNTPGEIQDNKIYGEV
YELLANYDYVENKEVSKVKILVTHAPPYNTCADLTESGDHVGSQGILKSIHEFEPTINIC
GHIHEAKALCKIGTVTDVANPGMLKDNGAVLIDIEDGSNYEISIISLNE
>A0A1U7T469|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Carlito syrichta|TrEMBL
MERLLDTEDELSDIQTDSVPSEVRDWLASTFTRKMGMTKKKPEEKPKFRSIVHAVQAGIF
VERMYRKTYHMVGLAYPAAVIVTLKDVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLI
NRFKIPVSCLIAFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEIL
AMVFAAAIHDYEHTGTTNNFHIQTKSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILVN
VSKDDWRDLRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPEGIDRAKTMSLILHAADISHP
AKSWKLHYRWTMALMEEFFLQ
>A0A7L2R3X5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Oxylabes madagascariensis|TrEMBL
RKLLDTEDELSDIQSDSVPLEVRDWLASTFTREMGIVKRRPEEKPKFRSIVHAVQAGIFV
ERMYRKTSSMVGLAYPAEVIVTFKDVDKWSFDVFALNEASGEHSLKFMMYELLTRYDLLN
RFKIPVPNLISFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMIHTGIMHWLTELEILA
MIFAAAVHDYEHTGTTNNFHIQTSNRMKPKYLQMERGTCDFQIVMHIHTALVDCKKKKGG
NVIGSLHISVAYSSLHRLFGQIFQWFQFSFELLSLTFVAFYFSVVFEPVINYHILSELAQ
SHTGSGDKEAALGLQFSPLCDRKSTLVAQSQIGNDKLSFSLFLSVIWGFFPFSSQNSLGA
VSNAEAQRRPGFKSAGDGGAHAENSLATVDLRAFKDNLMKIIQANKERWKELAAEG
>A0A1Y0NE88|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Curvibacter sp. AEP1-3|TrEMBL
MKIQIASDLHLDLLPKLEGAKPSLTEQTDADVLVLAGDIHDGYQGIRSFSNWKAGQEIIY
VAGNHEYYGHVYKAKQGQMQVCAADAGVHFLERNAIVIKGVRFLGATLWTDYRLFEPQYA
QLLAMQEAKDRLNDHRLIRLDKGAFSPVDALAIHTATRRWLKEELEKPFDGKTVVVTHHA
PHPNSVHQKYKDDLLSAAFASDVSELLQGAYLWIHGHVHDSFDYQVGRCRVVANPAGYVL
NRRSIRRMEDAQLENKLFNPSLVVEV
>A0A198XC01|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moraxella catarrhalis|TrEMBL
MPNITNNHTFNIVQLSDLHLTGDIGQAPSYQRFLAVFQTAKCLNPDLWLLTGDLVNDGNS
DAYDWLFNQLKTTKTPYLAVAGNHDVTHEIGIHLAHQERIHVPILPDQRLKNCFRYTFQA
GHDWQILLLNSSVSGEIFGLLTHETLLWLDQTLTTHSEQTIIALHHHPTKVGSDWIDAHL
LKNHQDFWHVIKKHAHVHTILCGHVHQVHTLHPLPAHQVQLLSCPSTDRQFMPFVDNFQI
ADTPAGCRMIQIDNKGIVSSYIQIVQNTHLFCLNNAN
>A0A1Y6JZB2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Levilactobacillus zymae|TrEMBL
MNKYTVIHVSDVQLTPPLPTAGTAAVANLQLVFDDIANQGTQPDLIVIGGDLIQRGSEAD
YRWLRTYLTQQSERLNAPIQVILGDQDNRDAFNAGYLGQAARPYYAYKQNHQNMDFYFLD
SKWETRRSAGWLVRDQLDWLNKSLHLAPRRRAFIFLHHPLDAPALRNLRYTLLQNNRELL
AILHGHNVGGIFAGHLHFAANYLVDNTLPVTVAGAASTYIDCRDPHQHEVHVAVSYNVIT
IERGIASVTVRPLRFDPVVQAVIPVGNTGFTKHRPRLLRPRRA
>A0A3P7L032|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Strongylus vulgaris|TrEMBL
IQDHNRVHAADVLHGCYYLTCHPVRPLIGPATSPDSLLPPPLPPAAPISSSMSTLELMAL
YTAAAMHDYDHPGRTNAFLVAAEDKKAILYNDRSVLENHHAAESWRLLQLKENNFIETLD
SAETKRFRYLVLEYILATDLKQHFEIIMTFNEKSSEMELLNESDRLLMAKMIIKMADINS
PTKPYGLHRQWTERICQEFYEQVGHF
>A0A4W4HQD6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Electrophorus electricus|TrEMBL
MIRDIDESNVDYEQFKKNLEYTASLLEALYRDETRQSLDMEDQLQELRPDSVPKEVHNWL
ASTFMQQARRPLRYPDYKPSFRSIVHAVQAGIFVERMFRKMSSTAMTDQPLAVVNCLREV
DRWNFDVFALDVGSSGHALKTLFTELMIRYELNSRFKVPISCLMSFLCELEQGYNKHNNP
YHCQTHAADVTQTLHCLLLRTGLVHWLTELEVLASLFAAAIHDNEHTGNTNSFHILTRSD
LAITYNDRSVQESHHLSSTFCILQNEQMNIFTNLSREEWVELRSLVIEMVLATDMSFHIL
QVKAMKHSLQQQERVDKAKALSFLLHTADISHPAKPWVLHSRWSKALTDELFRQGDKEGE
LGLTISPLCDRNTAPVAQSQIGFIDFIVDPTFSLLMDMAEKIIIPLVQDNPEPPEPINRH
RSAGNFLDTGLAAQLGITTLTLEPPLHVNSINRQPIGEGAGKHQTALVTLKVALFHSELI
HFMLLPMSSDSIILGFPWLSTHDSSISWSGAELLSWSKHCLQHCMSLPVLSTTVEGPESP
YSQSIPLPI
>A0A0N4VSL4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Haemonchus placei|TrEMBL
MCTSPSSCADDDPLLARHGDDLIVTPFAQLLASLRNVRANLISIANIQSADDGRHANRTA
KRPPLHNTPLPENVVTCAQETLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHF
AESSKSGTQVSKFLITTYMDKDDDDPTIEIEVPGEGPSTSSPQLSMGLLKKAQTAAMNRI
SGVRKLRAPSHEGHLPEYGVPCAKEVAVYMQQLNDWGPDVFKIDELSKNHALTTITYALF
RERGLIKAFEIPSSVFVTYLLNLEHHYRSNPYHNHIHAADVAQSMHVLLTSPVLTEVFSD
LEVMAAIFAGAIHDVDHPGFTNQYLINSSECFSVKRLNLLLPSYQHFIY
>A0A098BUU1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rhodococcus ruber|TrEMBL
MGSPRGAERIAEYPRPSHTLLHITDTHLVGGDELLYGTVDADARVQQILADIRASGVQPD
ALVFTGDLADRGQPDAYAKLRGLVEPVAQALGAQIVWAMGNHDDRATFRELLLDQAPSTG
PIDRVYHVNGLRIITLDTSVPGFHHGEVSQEQLNWLAQELETSAPFGTILAMHHPPVPSV
FDQAVLVELRDQAGLAEVLRDTDVRTILAGHLHYTTTATFADIPVSVASSTCYTQDLNVP
AGCQRGHDGAQGFNLVHVYPDTIVHSVVPTGSYATAGRPSTAEDAAQRLAEAGIRIPENP
DVTVRV
>A0A285AX28|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Klebsiella grimontii|TrEMBL
MLLAQISDTHFRSRGQKLYGFIDVNAANADVVSQLNALQERPDAVVVSGDIVNCGRPEEY
EVARQILGSLNYPLYLIPGNHDDKALFLEYLHPLCPQLGRDAQNIHYAVDDFATRLLFID
SSRAGTSKGWLTEETIKWLESQLFDGGDKPATVFMHHPPLPLGNAQMDPIACENGHRLLA
LVERFPSLTRIFCGHNHSLTMTQYRQAIISTIPGTVHQVPYFHEDTRPYYDLSPASCLMH
RQVDEQWVSYQHPLTHYAGPWMYDENISCPTEDR
>A0A3S7X2S6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Leishmania donovani|TrEMBL
MSLMPGYPVPRAQWVESAEGCAACNKRFTFFTSKENCPCCGRLFCSSCLSAQCALFPTAP
PKAVCLDCFRKAQDWRLSQLEKQQQTSTQADVGAATAPLSPSMAVLESKLSALEEEFYRA
KANARHLREENDSLIDLLAAKDTCIAELRDKLMTGVSAGAAAQSAEKLQAELQEAKDEKE
SMGRRLNEAEQRAAGAAQSSEAMRAQMQEHMQAKAEWESLEARLKSEARRAEHMLAQSLE
EMSELRAAMKSTNAHSEEQIRQLTAQLQSTVEANAHLQRDYDRNAEALRTAEQTRIASDA
HHDEELQRLREHLATATAALAQAQERYEREQRDAMKASDDAATAIAAEKQREIDTLSEQL
ALSSAAAQRLQGELDRAIKEATRLREEAALKAEAANTLTSELRTQLEAQGTTAQQEMPRQ
QEASVRLRADLAEKEHLVMKLRRACRHAGTTARAQLDDLRGKLVETKVAYEEGQRSWQAW
LGELRAALEVVVQQGAVEVAATSAPSTGAGMNARGTTKSRWAQPTIIEELQYPSVADVDV
RAIEPVPGLELWEFDTVAEAQRGGEADVLLRVGHQIALDLHLFPDRASLHRWACLLATVQ
ANYRANQYHNRVHAADVLQGVYALICSCPGLLAHMTTVEKRAVVFAAAVHDIRHPGRSEI
FLKHTFDATYVHYNGLQVLEQMHTATAFHLLATPELDFTRGSMDDTEALEFHGLVAALIG
CTFMGRHASLMEQWSRPLQDGKTYDVTVTADRQQVLSLLLHAADIGAQARGLAVALKWLG
VVEEMRAQGDEEAARGLPLSPGSSRSASLERGQIFFMEMFVVPLFDLVHQMFPSIESPMR
NLRTVHAHYCAALQETRAFPPPVQYRTATQPASNTAETSRAEALGTREAAVRKQEKAVEQ
SINRLREATAAVAGREKLLREREVALMRAETALKSQRLEKPSPTSSIGEEELLRAITAIM
AREAEVQRRVADVETMTAALEERETIASRLSEQLASIADKINRRRQVLRYREARVRELEA
AFRGERGADLSSSDYITGPMCRAVAKPLSTAAPLERMSPSSVQVVKLESALEKLTSALRY
M
>A0A0F0LY18|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium ginsengisoli|TrEMBL
MSSVSLGQYPPALRTLIHLSDTHFLAGNRPLGGRYDTSANLTATLARIDAMRIAPDAIVI
TGDLTDLGEPEAYASLRAVVEPFAARLAAPVVWVAGNHDERPALRAGLLDAAPTEEPVTG
VWDLGGLRLIALDSTVPGWHHGELGDAQLSWLSDLLAHPAPLGTLLAFHHPPLPSHVPLF
DILELRDQPALAEVVAGTDVRGILAGHLHYSTHGTFAGVPVSVAAATCYTMDLAAPAAKV
NGMDAGQSFHLVHVYADTITHSVVPVAGAEAGDYFDEAWLARMAALDPAQRLEQFSRKR
>A0A2X1JFL4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli|TrEMBL
MYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL
LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLAT
PSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>B7QGC0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ixodes scapularis|TrEMBL
MSSARASSSGVLELNVGGSAYATSLDTAQSSPVLAELAESGPRDSQGRVFVDRDGPLFRF
ILDFLRSGRLLLPEEFRELARLKAEAEYFKMDTLVACLSATSDLQVSASSLIPFPGQPGY
ITLGYRGTFAFGRDGLADVKFRKLTRILICGKVTVCREVFGDSLNESRDPDRGQDDRYTS
RFFLKHNSLEQAFDSLQESRFRCVCACGSGTSCGGSGEPLKPGMDSEENRWNHYNEFVFV
RP
>A0A1Q8KZG5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudonocardia sp. Ae706_Ps2|TrEMBL
MTTVVQLSDLHLGRPDPEGRAARAVAGVRALDPAPDVVVVTGDLADHGDPAAYAGAAALL
AGLDALHVPGNHDDRTAMAAAVGPVGDRLHRTGGCTVALLDTLVPGAPHGALSEGAVALL
TEAVRDPAPLLVALHHPPVALGHPVLDGMRLRDPGPLEMLLAARSDPTLVVCGHVHTPLA
TTFAGHPLVVAPSVAPALRWPDVPGAGGSDPVPAPGGVLHVLGDGPPRSRFLNWPV
>A0A379JUD6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas oleovorans|TrEMBL
MPSLPTQSTDSSVLLVQLSDSHLFAEADGKLLGMDTCDSLQRVIERVLQEQPQIDLILAT
GDLSQDGSEASYQRFRQLTSAIDAPTRWLAGNHDEIPPMQAACQGSELLEPVIDLGAWRI
VMLDSSIPGAVPGFLADGQLELLERALSEAPQRHHLICLHHHPVAIGCKWMEPIGLRNPD
ALFAVLDRYPQARTVLWGHIHQEFDQQRGNLRLLASPSTCVQFAPGSEEFQVSSEAPGYR
WLRLYADGTLDTGVSRVTGITFEIDYSVKGY
>A0A8B4RTT1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Acinetobacter junii|TrEMBL
MTFQVSTLSQKDFVMIQITDTHLLEYPHLEFVGMQPEQSFHAVIDLMRQTHPEIDLIVHT
GDLAQNPTPLTYHRYLEYMHSLSIPFFQTPGNHDDVNHFPFHEQDKTAPTVVELGNWYVI
LLNSAQPNRIDGKIADAQLQQLPKLLTQLHDRYVIIACHHHPFAMQSAWIDQHKLKNSSD
LLETIQLFSNVKAIICGHVHQDSITSWQGVEFLSTPSTCIQFKPKSEKFALDEEHPGYRY
IRLKANGEIETQVHRLSNSQRLSSSEVLGYD
>A8HNV6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chlamydomonas reinhardtii|TrEMBL
DNWEFDMWELQDVTQGHALSVLGFYLIQRAGLMDRFKIKPVKVARLLRAIESGYVDNPYH
SAIHAADVLQTMHVIIHAAQLHVHYLDALGLLASYYAAIVHDFAHPGLTGDFLIASSDPL
AIRYNDRSPLENHHCAASFGLLRRQELNALAPLSQSERNAFRKQVIELVLATDMKQHFSI
LSHFNTAPQPVDDTERLLSLQLALKCADIGHLGESLEVHNKWLSNLEEEFFRQGDKEREL
GIPISPLFDRSKQGVSKSQVGFYDFVALPLVHALSSAFPGSKPLMRW
>A0A291Q5Y9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Streptomyces formicae|TrEMBL
MPVIAHVSDIHIDTDDGGHSVDRTRAVMTYLNDLPYDLDAVIVTGDVADHGTPAEYAAAR
ELLASRHPLLVCPGNHDERAAFREHLLGEVPSAGPVNQSYVTDGFTLAVCDTSVPGEHHG
RLDGETLDWLSALLTDTPPTRPALIAFHHPPVPLHTPYVDVIRQRDEHRLAELTARHPNV
TAFLAGHAHTPAATTFANRPLLVAPGVVSTLRLPWEHQEHEGHHVHRDLPPAAAFHVLDE
ESRLTTHFRPVPLP
>A0A1B8P5M5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Halomonas elongata|TrEMBL
MHHPPVSVGSRWVDVLGLADAEAFWEVLATHERVEAILCGHIHQAFECRRATPHGEVAIY
ACPATSDQFLPRAETFAVDAAALPGFRVFDLGDTLSTRVERVVL
>A0A1X6Z204|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseovarius gaetbuli|TrEMBL
MHKVLVFTDIHILPEGEKIIGLDPFERFTQGLAHATARHPDAERIVLCGDLAHNAAPAEY
ARLKQALAGCPLPVDLMLGNHDRRAPFLADFPQVPVTEAGFVQHFQDIGDYRLILLDTLN
EAADDTHSGHLCAHRLDWLDHALATAGERRIVVFTHHPPMITGFSGMDWIGLHNRAELIE
RLVAHGGVVQIVSGHIHRTIQGAAGGIPVSIFKSPCHQMPMALGFQDPSLSIDEPGAYGI
LLLTGDGVIVHTEDFTLPDQKPELYG
>S7W5Z8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii (strain ATCC 50853 / GT1)|TrEMBL
MHRLLDWDFHVLALPPASAVLVTRDLLTQFALKANMDIPGEILMAFSVAIYKNYRPNPYH
NFYHALNVTQVLCLLLALPDVAAQFSPIDYLVLSVAALGHDLGHPGANNLFMTRFDCWPS
RIYQNVSVLENYHAASLFQILRHPAFNVFCSVSPTNFAPIRKRIISAILWTDMAKHFDVV
AKLQAKIQGEMVLAEGIIVTLTKPYLEGLLLHAADISNPMMDFELCRDWAFRACDEFYQQ
NKMEEMGGFPPSMPSFEHFDEYNVAKCQVGFIDAICKPLFNSLALMFPAQLGDRATQLQK
NRCVPLIIFPT
>A0A3M7P838|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Brachionus plicatilis|TrEMBL
MPSSSRRKKFLYFWTNLKLISTFVEPFNIFPILGSPRNKEKLNDNNQLSSHNYSDLSNFE
TLPLVDHIDSIKCSITRLAKIKDALGESSQDFFSLISKKDLKKNVEYFLQVLENVLLDER
KQVSLRLMSEDDVLSEVEPDAVPNEVRNWLSMTFTRSVSNMKKKAEDKPKFKSVAQAIRA
GIMVDSRQLYLGKNIFRFCKRWNLDTKIKHVVYPNFQTCYDRMKASLTCKKKQISKNFSW
IFIYSLLITTTKDMDKFKKSKAFFYKSLSEVISSHKCSVSKFKHVLFGCIAFQKYLNKKK
ACIY
>A0A1C7DBF2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Paraurantiacibacter namhicola|TrEMBL
MLIAQITDTHLTPARDADGQGNAARLARVLEALLEGPNRPDLLLVTGDLTDKGSEAAQAL
LAKALADVPFPALLAAGNHDDRITLVAQHEAMQLTGGFLQYAHDAGGLRVIVLDTVSEGL
HGGAFCEARAQWLREQLSQAGDTPVLLAMHHPPVTTGIEWMDAEGEHGWRSRFADVVEQA
GNVVGIVCGHVHRPIQSTLRGVPVTVCPSVSSPLSLDLTAIDTGVPDGRVLVHTGPPAYA
LHHWDGQQLTTHFAQAVDSEPLYSLTDESAAEVERIRRGR
>A0A142X973|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Gemmata sp. SH-PL17|TrEMBL
MTSPSRRDLFGAAIGAAALPGFISTARAADRKPVLRAAHITDVHITKDREAPQGVAAMFS
HMASQKDGKPELILNTGDAVMSVDGKTTGAKAAEHIAVWKEAVKSAPAPIYSCLGNHDVW
DGNEPTDAIPAEKKGFALMTGVLGMPAPYYSFDKNGWHFVSLNSMCNWPKYATLSPEHFD
WLKADLAKTKLPTVVLSHVPILSVTSQVYGDGCRKNNDNVVPGVWHHADCWAISEVFRKN
PHVKLCLSGHMHTCDRCEYRGVWYICGGAACGAWWGGSEYGFPPCYGKLDLFADGTFSYD
FVDYGWKARKWQGKELKD
>A0A377KM27|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Enterococcus durans|TrEMBL
MNILHISDIHFRREYEACEEGYKGMLATMQNPLIPLEQCIHHLLQQTPLDLVIISGDLTE
DGEIDDYRYLKTWLENALGETTILVTLGNHDIKEHFWVGWCDEAASSAPYNQIVKYPEFT
VISFDNSSYGYADGIVDDQQFQWLKKALEQEKDQPIFLVTHHHLLSHQSSIPKWPGTERF
LKLIAPYDIRCILNGHTHHTFTDEINGIPYFTVSSMSFVGEDEGDGFVRFEERHGYNLYH
LDQGRIVRQTTENFIPGNILKTLQMKD
>A0A2G8Y4S1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii COUG|TrEMBL
KVMSMIIKSADIGHGTLPWADHERWCNLVVQEFYEQGDEEKRLGLPVSFLCDRDQHDREF
FKSQVGFLDFVVKPLYEELKALETQLNLNPQLPIENICLKNLQENISEWKKKNEERRASL
EPAGLEVGGA
>A0A086M8A5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii RUB|TrEMBL
MHISCVKGRIVARQIDNVFTVIFAIEVLGKFVSYGLEYLQDPIESFDTIVVLTSFTLLVL
GFYVSGIGLLRILRLLSALALLHKYPDSKEKRPELSAGNSSKLEKASSIVEGLLTNVHIP
KYFKTELEWVWDSILANKVYDSHVVENEEEEEDQATETIIAGSDASRKTQAAVRASRAQS
RASKLPHGSSSMVVGTTNGRISGQILETLREPDPRMMDAALYKSETRNLDPLTATVGGMK
NSPSMFAKGSKSSNMMGSSASKSFRTERNKKAIDIISVLYQASQITGAEQEQVNEAMRPF
DEWQWDALHAGDVCDMNLLPVVFVRAIATFPTIMTKFNFDLDRLFDFLKVVQTSFQKNVK
FHCAAHTADMIQAMHYFLTIGKLGALLSEYDVFLCHFCALVCHFGHPGVTNTFLVKSRHP
RAIRYDDESVNENYVASAISCLVAREEYNFFGDKLPLWQVFRLHMIDILLNFDISKSAHQ
VAMFRTKVSIKFTASTPADKQLLLTILLRAADYSFTCRQLALYSKWKDRMIDEFFAMGDT
EKQLALTVSPFCDRELTNVDKCHVAFAEVAVKPLMTVLVLGLAPHLQKDVLDTLEANQKN
LMQKLDKSD
>A0A2N9CSP7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Burkholderia cenocepacia|TrEMBL
MFSAAVDSLNRIRPEPDLVVISGDLTDEGTEHEYRKLRELLVELRRPFVVLPGNHDDRGN
LRAAFPDHTWLPDEGELSFALDVGELRVVALDTSVPGLHHGELDAETLAWLDTELAEHRN
RTVVIVMHHPPFMTGIPYLDIYGLRNAEAFAAVLARHSNVDRILAGHVHRSMQTRLGRVP
VLTCPSTTTQIALRVEADAQPASFLEPPAYMLHRWTGRGQPAVSHLCYVGHFEGPFPFA
>A0A0K2VZY6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mesorhizobium plurifarium|TrEMBL
MKIIQVTDVHLGRRREIRYGANLNERLDRCIDHINQRHSDATLCIFTGDLTDDGEAESYA
DLKAALSRLTVPFRLLPGNHDRRANLVAAFPENGTDGNGFVQSVFDAPEGRLVFLDSLAE
GRVTGELCDKRLGWLDARLGEAAGKAAYIFLHHPPVELGLTLLDPLGLEQPQRLIDVLTR
HGNVRYIFFGHVHRDIAGTVAGIPFSVQRGLHARFMLDLVGDEMVEQAPPAYSIILIDGA
RVVIHSHDFLEQWPLWSPATGQRVR
>A0A086QYE2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii MAS|TrEMBL
MWFYSYLRHPNDVPSLCTHIRSSNIFLRLGPQYYLPEDERKSLFVRTCHLLYYLASLLFL
TTLTTYTAIKIPSSPSTTTELLSQLFPFNSIDDCNERLSCKVDCVLYAFPDLNCAKDDGS
LLTFGGNSYSSLYFYHYPGKDVPLQKEARTAWERCYQIMRETTGRLQFLQQDRETVERTH
TCFAGCKTNGAVTFTQKLTDGTPVVFDSGTDWLQMAPAGSLPQDTRPACNPSEPPSLLCV
EPTDECQHVTLRYQVCIGDTAFCFDIVRILITIALGVVWNVVLDAFVVWAMSIDDSDPQN
LARVASKCGLQIIATAIIVSSFFCLVASMTRILSMDANIARHGTLWTSFVLVIIIDQLFS
FLFSVLIWYAMLRRCGRQLPDESRFQYKIHPSPVLVKLKKATRKIVNYNGFEMFFTMLLG
WMVVDLTCRMILCQFFFDETAFLNQADRILEVVDFIILILFIVEICLRIAADGLKIYFSD
PINCIDFFLVFFGFGIRIVDFFIQINKGIGNVLFIMRLVRLYRLHRPPTGSLAIGKKEVF
TSRVERIIAVLNKALEIEELTTREKDSLKWLIQTISSGKLYEMGSEEKKKTDSHVQAWIS
IISTQSQSANQMADDMENILLERVKQMTKAGDAETDMPAVLQLEYGIDVSLDHAIEGYLA
NNLITWNFDVFRFHVIAGRAALPKLFVRCLQHQEVCSLFNLKIENMLRFAMELEKTSFST
TPFHNSIRSAEVLQAMHLFLAFFDTQIKGFFNSREILAALLAAVVWDYQHPGFSSAFLIK
TQHAIAIRYNDRNVLEHHHVAAAFSLMQKLGENDPLLAFPEDQYIALRKIIIQLSQSGSR
SNQTACLSLLKTKLQQAEFPRSITEDKNIILCNLMNAANYSFLGRPLQLYLQWSQKYMEE
LFMQGDRELELDMPITKNCDRHTTSEAVVQLGLIDGWAIPIYTTLAQTVPKLNAIVVSHL
RRNRLHWLDEQQEEDKSKEKQTKVTPIKRYSKTKQGSTEATGNGELSKPEATTVEIADGT
AGVPELRANANPLSEVD
>A0A090S8A6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio maritimus|TrEMBL
MTLDLEPNAPSSFSLEPNAIQLFKFDGDAVVSHISYISDSEGPYPFFDEQGNLID
>A0A1C3JGZ2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Vibrio celticus|TrEMBL
MNTVYQISDCHLSDESSYENLRRALEYINKDTACKTIFLTGDICCNPKSGDYVRLEAFIR
QHINDQSIYAIAGNHDDSRLMRKELKGSTICVTDKATICEREFVFLDSSFKPLGKQHPLG
SGRIDNRGMAQLKQQLRKANDPIVVVHHPVIPVGADWMKAILLENDTDVMNVLRKYRVRD
VICGHGHDGITATQQGITQYMAPSTAYGFNHSINEYNRSEKVGLSRISFSVHSIDYQAIY
FKIISL
>A0A653M183|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. 8BK|TrEMBL
MPGAPTKTTAVDRSVLLVQLSDSHLFADGAGKLLGMDTQDSLQRVIERVLLEQPQIDLIL
ASGDLSQDGSAESYQRFREMTAAIPAPARWLPGNHDEVPAMQDACVGSDLLEPVIDLGNW
RVILLDSSIPGAVPGYLSDQQLALLERALSEAPDRHHLICLHHHPVSIGCKWMEPIGLRN
PDALFAVLERFSQVRAVLWGHIHQELDQQRGPIRLLASPSTCVQFAPGSEEFQVDKTAPG
YRWLRLFDDGRLETGVSRVTGIKFEIDYTIKGY
>A0A7Z7RKL9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chromobacterium vaccinii|TrEMBL
MKVAQLTDLHLFADKRGRLLERDTHAALEAVLAAAAREPGLEAVLLTGDVSQDESEASYH
LAAEALAELDVPVHWIAGNHDDPAAMARVFAGYDFLWPLETLALGGWTFIGVDSCVAGQD
GGRIGDAELERLRQRLDAAGGGPAAVVLHHHPLAVGTPLLDDCMLAQASPFWQAATVVDT
LKLVICGHVHGEHSIAYRGKTLEVGPATCFQWTRGACDIEIDDRRGYRLFDFAADGYSVR
TVFV
>A0A086L6H2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii FOU|TrEMBL
MHRLLDWDFHVLALPPASAVLVTRDLLTQFALKANMDIPGEILMAFSVAIYKNYRPNPYH
NFYHALNVTQVLCLLLALPDVAAQFSPIDYLVLSVAALGHDLGHPGANNLFMTRFDCWPS
RIYQNVSVLENYHAASLFQILRHPAFNVFCSVSPTNFAPIRKRIISAILWTDMAKHFDVV
AKLQAKIQGEMVLAEGIIVTLTKPYLEGLLLHAADISNPMMDFELCRDWAFRACDEFYQQ
NKMEEMGGFPPSMPSFEHFDEYNVAKCQVGFIDAICKPLFNSLALMFPAQLGDRATQLQK
NRCVPLIIFPT
>A0A1V5V092|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|bacterium ADurb.Bin236|TrEMBL
MRALAALVIIRPMRINRVKIVTVSASHATVFWRANAPADITASCRAASDGNVADAVVSSV
NGRHFRAVFSGLKSDTAYAFHLSLNGRILHSGEFRTLRPAPGDFIFRFATVNDIHIGEKI
YGLIFLPGLNLFPVTPGLKLDIDGEPFWKYTNETAIKELNKLDLDFIIVKGDVVTDHTEE
NIRTAKEMLDTLRHPYRVLRGNHDRAASPKTDFFLQAFPAVTELQSFEHKGRGFILLDDI
HPATGNTRFSPRTIDLFKSEMKKMSDIPAFVFAHNPPLRKFERAPDNRISDFLDIIDEHP
AVAGVFCGHTHGNKVAIRKSRGKQVLFVETAAPMDYPGGFNIYDVHTDGYVQTCVRPFCA
KSARWYEMCEKAYYGLAASGLFGDISDRNFVLPVE
>A0A0M6XX74|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseibium aggregatum|TrEMBL
MTLIAHMTDLHLRPRGLPCYRVSDTNMLAERAIKSLQNLTPKPDALVITGDITDRNDPRE
YALARSILSRVDMPVYLVPGNHDGTDVMRRELGSFPGLSGSLEDKICYTADIGDIRLIAL
DTHIPGDPRGRLGQAQLDWLDSRLRESAKTTLIALHHPPALSGIRHMDDIGLVDADALAE
VVSPHRHVARFLCGHLHRPIIASFAGKVMTLAPSTGHQVVLDLTEDGPAMFNFEPAAYFL
HYHSPKTGVVSHMAYVEAYPGPYHFFADEGVVWPGDET
>T0YUW9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|mine drainage metagenome|TrEMBL
MRPGGSGPERVFEAVNLLADPIYEYCSITKQLPDGASSEQALLDHPWLQRQRRIHQLQSA
WWVFHTAEHSRFQHAVGAMHLTGLFTDHLYSSLRESFPRLPSQPLVVETMRIAGLLHDVG
HGPFGHFFDTQVLAPYGIDHESIGRELVMGPLADLIGSLRRSPGGAFEPGEAVDPRWVAF
VMAPA
>A0A1J5RR92|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|mine drainage metagenome|TrEMBL
MVALHSNTMRHPFLLLAGLPLLVIAARAASDRPLSPLPIPGEMVMASPADPGRFTFVVGG
DNRSVARDVPPPPTAAQIFAETRLLRPAFALWTGDSIYGSDDTPGEAAHEYAGFLRLAAT
GDTPVFNAPGNHEIFRRPELERVYESCMGRLYGSFDYGRSHFIALDTEEADRAPGVGPAQ
LEWLRKDLEANRGAEHIFVFSHHPLFPTPDHPRAGFASAANRDEVHRLFVRYHVTAVFSG
HEHLYYASVHDGVRYIVTGGGGAPSDGAPQDGGFQHYLLVSVDGNAVKIQVLQPWRLFEK
VGPVQPDGSCTAMVMNYGHDPLSVLVAFPTDQLGAGATATASWTYKGGTHPVPAEIVAPL
HPGETDVRVMARQGRGTLVVLTPATK
>A0A1J5SVG2|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|mine drainage metagenome|TrEMBL
MPAVFVHVSDIHFGQEKDDRLHINRDVKQQLIADAREVVSAIAGGFAHGILVTGDIAQSG
KWTEYEDAGKWLDELAASIGVEIHRVQMVPGNHDLDRSKLSFSGKQILDHIRGGGAKEYE
EILNNPTDRSALFARFEDYSRFSFGYNCTLNNEGAFDSEMEVTLAPGRSIRFIRFNSSLL
CHGEEQDEHPELMIGARQFTIPRTNGVENIVLVHHPLNWYKDQDQVKDYIRSRARVFISG
HEHDPKVSVDNVEQGCDVMMLAAGATVPYKSNDVYKYTYNIIEFDWDRENDGLIVTMHPR
AWNPQRTSFEADDKRLGGKDPIFHLACPFFRNTDKPKDSSTTHEVLLSEEESVQSVKPTI
EMIPVGMVGEEALTMQPKAEGYEIARLRFFRDLLEGERLRILIDLDALEMNSDERITQGL
ERKLLDMLVRNGKLGTIEMMINNLIDERRKKNG
>A0A1J5PQK8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|mine drainage metagenome|TrEMBL
MTARAKSLNEERPAARIAAIDVAGVALVADLPAALFWEEANLLVVSDLHLEKGSSFASRG
VLLPPYDTVATLGRLASVIARHDPRMVIALGDSFHDRDAHERLSAPDREAIAELQARRDW
IWISGNHDPALPSDLGGIVATEVAIGGIAFRHEPTGARGEIAGHLHPKARVATRGRSMER
RCFASDGERAVMPAFGAYAGGLSIRDEAFARIFQTPGFMAHVLGDHRLHAIAASRCCGSR
APLFTL
>A0A1J5Q2K3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|mine drainage metagenome|TrEMBL
MLFGWQMSLMKLNILSDLHLSCGALEMPRNDADIVILAGDIARPKDAVSWALGFAKPVLY
VPGNHEFYGGSIVEAAEELKKLCAGTNIHVLDNDQVTIDGVRFLGTTLWTDFMHGTDDEQ
RSRAMQEAQRFMRDFSIIRVDDPVPRLFTPVDAAALCRADAQWLENRLAEPHAGPTVVIT
HHAPSRQSIHSRFAGSLLNGCFVSDLQHLVDGQRVQLWVHGHTHDTFDYMLHGTRVVCNP
RGYAKEGVNENLLFDSNFVVQFGPSTQDGELE
>A0A3P5WMW5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Arthrobacter ulcerisalmonis|TrEMBL
MEHIEAEHPRPRHFLLHLSDPHLLAGPEPLYGVADSDSRLAQLFEEVKASGAKPEAVIFT
GDLADKGDPEAYIKLRSIVEPACKDLGAQVIWAMGNHDDRANFRRELLDQPGSDEPVDHS
YFINGLRVITLDTTVPGFHHGEISQDQLEWLTRQLDTPAPDGTILALHHPPIPSVLDLAV
LVELRNQSALERVVRNSDVRTILAGHLHYSSTASFAGIPVSVASASCYTQDLNVPVGGTR
GQDAGQAFNLVHVYEHTIVHSVVPLGSAATVGEYVSAEETTRRLAAAGIRIPQTTKARVS
PRLGMPSRFL
>A0A0V0YB55|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Trichinella pseudospiralis|TrEMBL
MKPNPKIILYCRRHHRLAVAGPAITDPLASQQNFQLMDHSSQFYFLTLRKHACRLRYIIY
QMHRGEMSSKDLIDNLEYAASILESTYVDSCRLQVEEQIDQIDSEDVPEEVRKWLALTFT
QSVNEQHQKVSFKSVANAIRSGIRFDRLARRSMSSGLDIVPDNVAENINDWNFDVFLLNE
LSENNALKCVSMALFSKYNFLNKYKIPMVKFEAFLNKLQQGYSKHNNPYHNLVHAADVTQ
TAHWLLAQSGLVECLTDLELFAYLFAAMVHDFEHTGHTNNYHVQSSSDYALIYNDRSVLE
NHHVSAIFRLMHDSSQYNILEKLTKEEIRQFRNLVIEIVLCTDMSTHFAQVKDVKQMITS
DEEIDKTKALSFLIHCSDISHPAKIWPFHFRWTEQLMEEFFRQV
>A9IHY6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)|TrEMBL
MTRILHLSDTHFGTEREPVVQALLALSDALQPDLVLLGGDITQRARRSQFAAARRFVQAL
QRPVLAVPGNHDIPLFNLAARLFDPYGGYRRALGAVLEPVVETDGLLAIGVNSTRPGRHK
NGQVSAAQVVRVAQRLREAGPGRLRVVLLHHPVRAAVESDHANLLIGRDLAVPAWVDAGV
DIILGGHIHLPYILPIHGAAGPAPRQAWTVQAGTAVSHRVRGGISNSVNVIDHMPDNERH
RCSVQRWDYQAEAGEFRAQGTQMLALHRGI
>A0A2I3N7P8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Papio anubis|TrEMBL
MTVKYITIVIGLFFRGEASVVDLKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAV
PSEVRDWLASTFTRQMGMMLRRSEEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPA
VIEALKDVDKWSFDVFSLNEASGDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEV
GYSKHKNPYHNLMHAADVTQTVHYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNN
FHIQTRSDPAILYNDRSVLENHHLSAAYRLLQDDEEMNILVNLSKDDWREFRTLVIEMVM
ATDMSCHFQQIKAMKTALQQPEAIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEF
FRQVPCCSLSIRAVITGYLMNFVSQ
>A0A517ZEJ5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Maioricimonas rarisocia|TrEMBL
MPAHLPAHNRRQFLATVGAGLIACSSRGFAGDVDDELVYLLNDTHIGEKHPPHSPVPTHL
RQVVTELVEMSEKPAAVLINGDLALHDGQPGDYRHFAKLVAPLRDVNVDVHVTLGNHDNR
EAFYDVLEEERPADPPVESRHISVVSTPHANFFLLDSLTKTLVTPGTLGEQQRQWLAEAL
DAHADRPAIIVAHHNPRLGGDPLHFPGGLVDSQELWQLLADRRHVKAYVHGHVHDRTYAA
HEGIHIINTPATSYVADPAKSTTGWTVARLRPDGITLTTRTTDPLHPWNGEQTTLTWRN
>A0A0S4WZ63|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ralstonia solanacearum|TrEMBL
MPPSTEIDMTEARMNKNITVVQITDLHLLADRDDQLHGYCTYSVLSDTIDAILDHNVKPD
VCFVTGDISQDESDASYDLARSELERLGTPVFWIPGNHDDRDKAEAAFGKSDSIRRLMKL
PTADWDFIYLDTCRRGADEGYLNDEDFDRFVSNVRASVGEGKHVAVVMHHHPVPTQTPLM
DTYILQEKERLLEVLDDHPQVKLVICGHVHGDYQLQYGNQAIEMCPATCFQWEKGASTIK
TEDWRGFRIFEFSQSGYRSALVSV
>A0A1Y5NUJ8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|uncultured Microbacterium sp|TrEMBL
MHAPRGVHHVFRKHPGNIGATADRPARSVPTGREPMRRAEHPAAERILLHISDTHLRAGI
PHLFDSVDGAASLTRALDGIEASGLRPDAVVFTGDLADLGEPAAYRVLRALVEPFAERLG
ARLLWVMGNHDDRAAFRARLLDEDGRGDPLRPVDRVDELDGLRVVTLDTSVPGHHHGEVT
PAQRAWLRDVLATPAPLGTILAMHHPPIPSVLPLAASVELRAQASLAEVVRGTDVRAIIA
GHLHYSTFATFAGIPVSVASSTCYAQDLTVPVGGSRPQDGSQAFNLVHVYDDTIVHSVVP
IDAPRPLEHIDAGEALRRLQAAGIETSLTASRVAPPTEPLTVLR
>A8GB67|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Serratia proteamaculans (strain 568)|TrEMBL
MMKKVLALCLSGYCALAQAGFDVVALGVDGGVGGGNLTSYLIRSDNQTQYLALDAGSLLP
GIAKGLEKGSFPQVTPELAAPYTPQGYIFRQLIGAYFISHGHLDHVAGLIIGSPEDSKKN
IYAQVDTILTLRNHYFNWKAWPNFTDSGNGSRLGTYRLQTVRPQQRVTLGMTGLSGVMYP
LSHDRYPSSMLLVSDRSGSFAYFGDTGADALEQSRNLDSAWRALGPLIEQKKLKGMIIET
SYPNEVEDKNLYGHLTPAWLQKELKNLTQYSGGEGSLKDFPVVISHIKPSLKQGEDVRAT
IKQQLEQGNSLGVKYILMEQGDRQTF
>A0A151AZK5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moorella mulderi DSM 14980|TrEMBL
MCENVIHRLLQRRVMKPVIPGLLLFLLLGLVARSSSMVRVEVPLQELPAELDGLTIVHIS
DLHYGSGRFRSEDSVVQITRLISSLHRDLIVFTGDLLDRSADPALADPCHCKGLRHPWVC
TPSRAITTTTSAKK
>A0A1L9P2M6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Planktotalea frisia|TrEMBL
MTAILQITDTHIVAEGVLVSGKLDTRAALKRLVSRLCSIQNKIGTVDAVLVSGDLSDDGS
SESYEQFKALIAPLGLPLHIIPGNHDAREPMRAAFAEQLPVKGPLNWHVQIGKVHMIGLD
TLVEGHRHGTLTDETLTYLRNALIRADGAPVLLALHHPPFLSGIRFMDDIGLTNQGAIKQ
AVSRYSGKMHIVCGHIHSMMLTNIAGHVAISAPSPNSTFEFDQRDEAPVGFFTQEGGCLL
HRWNDGFQTVRIGPVAGAGPFSF
>A0A447IEB6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Devosia equisanguinis|TrEMBL
MKILHISDLHFGHHDPELAAGFSNDINAQRPDLIVASGDFTQIGTKEEFEQAREFLDTLS
APVFAVPGNHDVPAINILRRFLNPYGLYKRYISPDLEPFLEMGGVALVGMRTSRRARLEW
NWGHGSISRGQLDDLAERFAQASPNAVRVIVAHHPLLFPTEPMLQKTKRVKRADDALETF
AGLGVRLVLSGHFHLSYVRKHESNEKAREGEPMGLSKSVRAPILIAQAASAISTRLRGEG
NAYNLIDIGDQITVTVREWRDGAWTTRDRATEPV
>A0A239S9J3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pandoraea sputorum|TrEMBL
MTKFIHITDTHLVTPGEPLYGLDPYARLVACVDDIIENHTDARCCVITGDLTHRGEATGY
AALREQLDRLPFPVFPLMGNHDLRSAFTESFPDRLRDADGFVQGRFDLGGAGDGTLLMLD
TLDEGQHGGLYCESRLAWLARQLDEAGDRPVYLFMHHPPFDIGIPSLDHIGLANPQAFLK
CVSGHKNIRHLFFGHVHRPVCGSWHGIPYSTMRGLNHQVPFDMHTVDLVRQSHEPPAYAV
VLLAADQVTVHFHDYLDKSALVDEDAGMRSM
>A0A654SJA1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chrysosporum ovalisporum|TrEMBL
MARQKGTISKFLAPLTQDTFKQVVTEVEQKLQIVHQTLSMLNSQGFETILQEMLHSITFK
TGELLGAERTTIFLLDEEKKELWSILAEGEGEASLEIRIPADKGIAGEVATLKQVINIPF
DFYEDPRSGFAKQQDKRNGYRTYTMLALPLLNEQGKLVAVVQLLNKLKSSNNPDDPISER
IDTEGFTKADEQLFQEFAPSIRLMLESSRSFYVVTQKQKALAGLMKAIKSLSQSSLDLED
TLHRVMDEAKELMNADRSTLWLIDGDTNELWSKITHDNGCTRELRIPIGKGFAGMVAASR
QKLNIPFDLYDHPDADTAKEMDRENSYRTCSLLCMPVFNTDQELIGVTQLVNKKKSGDFP
PYDPAMWPKAPECFQASFDHHDEEFMEAFNIQAGVALQNAKLFATIKQQEQMQQDILRSL
SNGVISTNKAGLIISANASAKHLLGLQPEDRLEGKLITEAIAIQEGDFSKWYQQAIQRND
VKISQKYFPDRTLVSHGVDQHSINLSINTIADATDQEQVRGAVVVMEDISDEKRLKSTMY
RYMTQELAEELLKLDDAKLGGDRKEVSILFSDIRGYTTLTENLEAEEVVSLLNEYFESMV
EAIFKHKGTLDKYIGDAIMAVFGSPLPLKDHAWMAVQTSLEMRHRLQEFNQRRHAAGKSR
IKIGIGINSDTVISGNIGSSKRMEFTAIGDGVNLGSRLESITKQYGCDIILSKNTFKPCQ
ERIWTRELDYIRVKGRSKPVAIYELVGLRSDPITREKLQLIEYYHKGREYYLNRQFKYAR
GEFAKVLGVDNQDKAAMLHLLRCQHWLQSPPTDFEWDQGAWTFEEK
>Q5ZU56|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)|TrEMBL
MKIIHISDLHFGMHQPKVLNAFLQETALDKPDIILISGDLTQRGLSYQYRELCSFINQLP
AQTLSVPGNHDIPFYNVPARFIFPFRQYKRYINPDVTTTFENDCVRILGVNSVNPLQLKD
GKLSHETLNRIKRYFKPDDEKLNLLFFHHNFDYMEGLHKPLANAQTLLSFLKQSTIHLVC
TGHLHYAHLSLIAKNNGYSCLALHAGSLLCPRSKDNLNSYYVIEANQKKCRITWRVFDQE
HFTARSIYFIDFNKKNASFEHLNPVTDDA
>A0A163H2D6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Prochlorococcus sp. MIT 1303|TrEMBL
MRLVQLSDPHLVAFNDQLVRGHNPLLNLQYALQQASSHSPDLLLITGDLCHDESWCGYVL
LRDELQSLNPATKVAVLPGNHDNTFFIKAALGRHAFTAPADLNVDGVRLILLSSHVSGQI
AGQLGQSQLQWLDSRLSDIEQSGRPLVVALHHPPLPIGHSWLDPLGLLDGEALIQLLTPV
EELCAVVFGHIHQHWQEVFPGRKDVLLLGCPSTLCSFEAAQPCPLGREDEPGGRLIELDA
SGTLFEMLLRWSNPDLDNGYVTR
>A0A5C5V108|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Blastopirellula retiformator|TrEMBL
MPLHIPAVGRRQFLTQSAAALAGLSILRIGYAAEGDQAVTLALLSDTHVPETPMVEARGV
NMTANLQKAVEEINALPTKPAAVLFNGDCAYLKGLPRDYANFAQCVQPLIDTGQELHMTM
GNHDNIPAFYGAMASQKPEQPLVESKHVGILETPYANIFLLDSLMTTNVVTGELGAAQLK
WLSQALDAHANKPAVIMAHHTLDKSPPQVGKAISGLADTAELLELLHSKPHVKAYVFGHS
HVWAHTHEGDLNLINLPACAYVFNEAQPNGWTLARVNEKGIEFELQAHDKSHKKHGQVFT
VKWA
>U6F701|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Lactobacillus helveticus CIRM-BIA 104|TrEMBL
MHHNLYAHNPAVNKGYVVDDAVELRRLCSRYNVKLAFTRHINAQNIMDPQETTPTTEVVT
SSFCSNDQGYGVVRVHSRHITYVRRNFDMTRYLTDQEKENYTLEHFHKYLKDLQLGSISA
DMMQSELNKIHSSQAHQVLIKHHPEYRLYLEILYDTTSHSNLQVKIRY
>A0A0M7AZH1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Roseibium album|TrEMBL
MTLIAQITDLHLRPKGLACYRVSDTNMMAERAVRSLLSLTQQADAIVVTGDLTDRSDPRE
YAVARELLSRFEVPVFLLPGNHDSSEGMRREMAGYPGIGENRDGKIFYSAMIEGIQLIAL
DSHLSGHPQGYLGNEQLSWLEAALRKCDAPTIIALHHPPALTGIEHMDNMGLNDAAALEE
VLSPHTHVQRILCGHVHRPIVTSFAGKIMTLAPSTGHQVALDLRENSPAMFNFEPAAYFL
HSHSEKTGIVTHMAYVENFPGPYHFFADQGVTWPGDEN
>A0A422PC70|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Trypanosoma conorhini|TrEMBL
KAEAMLTMATQLARDNLDEAVLANSIMNTAKALTESDRCSIFLVKDDTLEAHFEDGNIVT
IPISAGIAGFVAQSGETVNISDAYADERFNREVDKATGYRTKTILCMPVTYEGSIVAVAQ
LINKLDMVTESGLRLPRTFGRRDEELFQTFSMFAGASLRNCRINEKLVNEKKKSDAILDV
VTLLSNTDIRDVDGIVRHVLHGAKKLLHADRSALFLVDKERNELYSRIADSVAGKEIRFP
CGQGIAGLVASTGVGENIPDAYQDPRFNREVDKQLGYRTQTILCEPIVLNGEILAVVQLV
NKLDHTGEVTVFTASDRETFRVFSLFAGISINNSHLLEFAVNAGREMMELNENRALAGGR
RASVRNIKRPLAITDRERDAVREIELGHLDITSVEFDLFYVRENMEEPLDAAAAVAYRLI
LGTGLPQKFRCXXXXXXXXXSCGGAAREQAGSHRGGDCVHGERPGDISCFLPFRRHIH
>A0A0F0LY77|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Microbacterium ginsengisoli|TrEMBL
MSHIASQHPAPEHFILHVSDTHFVGDGDLLHERIDSDKNLAELFDGFTKANARPEAIVFT
GDLADTGRPDAYERLRAIVEPAAEKLGAQVIWVMGNHDERVAFRRGLLDEEADQSEPVDR
VYDVNGLRIIALDSTVPGQHHGEISDEQLAWLRRELEVPAPDGTLIALHHPPVPSPIGLI
ALVELRDQERLAEVIRGTDVRGILGGHLHYSTTSTFAGVPVSVASATCYTQDLAVAYPGA
RGQDGGQSYNLVHVYGDRVLHSVVPIGQFPTVYEMTPEMLEAFMNMTPDEQLAAVNASAG
E
>A0A377DLG4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli|TrEMBL
MRQKRHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDW
NGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQPDTAS
EGY
>A0A379L4M9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas putida|TrEMBL
MHADHPRPVHVVQLTDAHLFADPAGSMLGLKTRESLGHVVAQVRREQPLVDLLLCTGDLS
QDASVASYEAFRELTAPFGVPSRWLPGNHDEARIMAEVAPELVQAVTDIGAWRIVMLNTA
VHGATHGLLGDDQLAVLEAALKGAGGRHCLVCFHHQPVDIGCAWIAPIGLRNAQALFDII
EGYPQVRALLWGHVHQEWDEVRNGRRLLATPSTCIQFAARSEDFKVSEEQPGYRWLRLHA
DGRLETGVERAWDFEVKLDFDSPGY
>A0A1R3TMT1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Agrobacterium sp. DSM 25558|TrEMBL
MAAGITPRPNLLPESSPMKIIQITDTHLMLSGQSVNGVDPEKQLRAAVTDILDKHMDTDL
LVMTGDLCNFGDPEAYDILRDILAPVPFDVRLMLGNHDDRPNFRSAFPEHPHDENGFIQS
FMDTDFGRLIFLDSHEAGVIGGIYGEDRMAFLADALASAGNLPVTIFIHHPPMDCGIAHF
EKIGMHDDGAVMRVLAAHKGGIRHIVFGHIHVPLAGTSAEGIAFSSGQACAHRFITDLTS
PKPYWTGGNPCYRIINLDAQGLRAYSVEVGETIMGQAPICDGP
>A0A238K502|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Octadecabacter ascidiaceicola|TrEMBL
MDKILVLTDLHLRLQGQTIIGLDPIARLGEALDAALGDHPDAKAFILMGDLTHSGFKEEY
ELLRDMMRNCPIPVTYMLGNHDLRAPFRSVFPDVPVTPQGHIQHIIDLPDHRIITLDTHQ
ADVVPAHSGFLCDDRLSWLDAALAGANGRMPLVFTHHPPHTIGLPGMDAIKLTNGSDLLE
RLACTKAHLFCGHVHRTISGQAQGVPFTMFKSPCHQAPLDLHDADSTLSNAEPGAYGLLL
LAKGGVTAHSEDVGLNFPPMSGADALPDH
>A0A226N518|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Callipepla squamata|TrEMBL
MLGEATGERRLLDTEDELSDIHSDSVPLEVRDWLASTFTREMGIVKRRPEEKPKFRSIVH
AVQAGIFVERMYRRTSSMVGLAYPAEVIVTFKDVDKWSFDVFALNEASGEHSLKFMMYEL
FTRYDLLNRFKIPVPNLITFAETLEVGYSKYKNPYHNLIHAADVTQTVHYIMIHTGIMHW
LTELEILAMIFAAAIHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEE
EMNILANLTKDDWRELRSLVIEMVLSTDMSGHFQQIKTMRHTLQQAEG
>A0A1J5JV88|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Moorella thermoacetica|TrEMBL
MKKFAALFLAVVIAVTMLAAPAASSAAGTPQYDLGASAQPDHITLTWTQDPLTTQTITWR
TDITIARGLVQYAKAADKASFPGKAATVEATVQKFTSDLGDMNIHTATLTGLEPGTEYIY
RVGDGTNWSDIHTFTTEASNTHSFKFLIFGDSQSGDPLNPEYKPWHDTIQNAFKTNPDAK
FFVNVGDLVEQGQNYVHWNKWFEAAKGVIDTIPAMATQGNHETYNPPDGHSTKPIFWTTQ
FKLPQNGPEGLKGQAYSFDYGNAHIVMLDSQEEEEEKGVAGDILAAQKAWLEKDLQNTNK
PWKLIFFHKTPYYNKATRTNEDIKAAFQPLFDKYHVDVVFNGHDHAVARTYPIAGDKFVS
SPAKGTIYYLTGRSGNKYYPDLSAKVWDAFFYDPQDQPNYIVAELNGDKLTLRAMKQDGT
PIDTYTIDKASGLDTPQTIVPPKYNSTRLVIFGNMLQQPLLPVTPKQVNGQWYIPVRAFM
QFLGGNVAWYDDGSVTIVYGKDKVQMASKSARATINGQEVNLPGSSLMDKNTLFIPAADL
EEFFGFSYKYDAATNMLMFTK
>A0A3G8C529|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas sp. R4-34-07|TrEMBL
MRESLLVNRPFLVAQISDLHLKAGERLTYGVVDTLGALRRAVDHLNASHPRPDIVVISGD
LVDFGRADEYAVLHPELARLHMPCYLVPGNHDTRGPLLEAFRDHAYLPSSAQGPLDWVVD
EHPLRLIGLDSTIPGGHGGQLLDSQLQWLDAQLARRPDAPTLLILHHPPFMSGIGHMDRE
PFINAAALETVVARHPQVERLLCGHLHRPMQRRFGGSLSCVCPGTSHQIVLDLQDAAPAH
FNLEPAGYLLHRWDAQQGLVSHNGVFGDYPGPYPFYDAHGLID
>A0A090ESP0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mesorhizobium sp. SOD10|TrEMBL
MKIIQVTDVHLGRRREMRYGANLNERLDRCIDHINQRHSDATLCIFTGDLTDDGKAESYA
DLKAALSRLTVPYRLLPGNHDRRANLIAAFPENGTDGNGFVQSVFDTLEGRLIFLDSLAE
GRVTGELCDSRLGWLDARLREAAGKAAYIFLHHPPVELGLTLLDPLGLEQPQRLIDVLTR
HGNVRYIFFGHVHRDIAGTVAGIPFSVQRGLHARFMLDLVGDEFVEQAPPAYSIILIDGA
RVVIHSHDFLEQWPLWSPATGQRVR
>A0A1V5MHR4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|candidate division TA06 bacterium ADurb.Bin417|TrEMBL
MSKDAAKKESLELFPAAESGRLFRFIHISDTHLRSDGSFTGELIRVIEQINLAGADFVIH
TGDIADEGAIGGLERFMKLAAGLKVPVRCVRGNHELEGEAGRESGLYQRLIGQPLYYSFQ
HRGFRFIGLDTAAAQHMGAISPEQLDWLENELKAAGRSAFIFAHVPLRREWEQGAHRWYI
TENGERLAALLEERPPVAFLAGHLHWTNAFTRSGPTLHSTAPSLGGLYNYPNRNGYLVWD
VYPDRIVQYYKYLYLPWEPSVRNVVKLNGSDGTSTR
>A0A1V6DD85|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Planctomycetes bacterium ADurb.Bin126|TrEMBL
MPENFSNAISRRQVLKGGLMLAGGLAVLGSRRGWAADERSARWAFLSDTHIPADTENNYR
GFYPYRNLEKVLPQVAACSPKGLVITGDLARLTGEVGDYDNLSKLLSPLTEERPAYLALG
NHDNLANFQKVFAKPSGERQSVKKKHVLAVDAGPVRFLLLDSLLATNLTGGLLGKAQRAW
LEGYLKGGGDTPTILFFHHTLGDADGDLLDANRLFDIIRPARAVKAVVFGHSHAYGFTEL
DGIHLINLPATAYTFGKAQPVGWVEARLSAEGAELVLHAIAGNTEIDGQTKTLRWR
>A0A5P9EG48|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Marinobacter sp. THAF39|TrEMBL
MTIAHTARPLKVLQLTDPHLMASADGALLGVNTRDSLAAVIDEVLRNHGQPDLILATGDL
TQDASSEAYRYFGEQLKAFNCPSLWIAGNHDDSDLLASIAAEFQAEQKQVVQGGWHFVML
DSSVHGKVFGELSPPELAFLDESLSQQPELPTMVCLHHHPVDIGSDWMEKIGLKNRDAFW
QVIDRHPQVKVVLWGHIHQDLQQQRNSVQLLATPSTCIQFATGSSKFAVEPLAPGYRWFE
LEASGQYSTEVCRANEFKFDLDEKSTGY
>A0A3B0YSH8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MQQNRTDKQPLRITQITDTHLYADADGRLLGLNTRQCLDQVIQLAREHDAFDLAVASGDL
AQDGSEAAYQQVRKQIGQLGIPVYCLPGNHDEASAIRKHLHGEEFHCVRSHLAGGWQLIF
LDSTVAGQDGGHLNADELKALSQTLDTHPDLPTVVWLHHQPVCIGSRWLDTMAVDNPDDF
FAIIDCHPQVRAIVWGHVHQSFAQQRKDVQLLASPSTCLQFLPASEEFTVHEVPPGYRWL
ELYPDGSLQTGIQRLASIPGNIDLSATGY
>A0A3B0RKU8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|hydrothermal vent metagenome|TrEMBL
MLIAHISDTHITSPGNKTYGVAPMAENLARCVEHISQMVPRPDVVFHSGDVTNAGTAAEV
RHAVALLEKLDCPVFMVPGNHDNGRVLSDECGSTICPMGDYVVDDFPLRLIGMDSTDPGK
PGGKITTAQAGWLETQLSSEPEKPTLIFMHHPPVKCGVRESDRDGFVGADLLGEVVGKYN
NIERILCGHIHLLIHARWQGTVVTTAPSTGMQLGLDLTMEKEPAFSLTEPGYLLHDWTQQ
QQLITHTVSLARGEGPYLFEEQG
>A0A1V5Y006|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|candidate division BRC1 bacterium ADurb.Bin183|TrEMBL
MKKLIIFILIFAAAAGAGEFRFAVLGDSHFDNPEIFERLVQEINLLRPAFVIHTGNMIEG
YTYDPEQIRKEWECFKKQIAHLTMPFYPVPGNRDIATTPLQAIFAEIWGKDKLYYSFDYR
GSHFIILNTDYNLNYGIISADQMTWAERDLEKNAAAENIFVFMHRPLWRDGASNWKAFAA
LLKKYPNVRSVMAGHEHEYCFEEVDGLRCFILNASGRMDYYAPAVGYFHHFLMVSVEGTT
VTEALIPAGSIKPADYVTRQEQDRASLYLLPPSGGQIPDPSLEPLDILYTFYIRNYSKEI
NVYTVRWETPNPAFTAEPREQALMLAPGRLEGVSVRLKAPARFYESYSLPYALIQTYYNT
YSGESITLTSRHELNVPPRTVARFAKNPPIIDGMLDDTAWMSADDITDFKINRGGDPAQM
QTWARTLFDEDYLYIGVHCAEPNLDKLVKLASPPIPFTWGDDEVEIFLDPEHDLQTFARA
FVSAGGVAFSTLPEKGIVQPWFEHAVHMGKDYWAVEYKIPFSVLRQDDVPTSATTWGFNV
RRHRQKPQREQSDWSKMSDYPNEEPWRFGILHFER
>A0A368F433|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ancylostoma caninum|TrEMBL
MAAELLVQGSQLLISEEDVRKLTNEAIKDWRYWSPNFARFSFSPRSIGDGDAYMSASMTM
FNDLGFTARYSMNKKKLASFLLRVARGYREVPYHNWSHAFSVAHFCWISLRTPAVLHGLD
ELERLALLIACLCHDIDHRGTTNAFQLQSKTPLAQLYSSEGSVLERHHYAQTVQILQMNE
CNILDQLTRTQYQTVLSHIRDVILATDIAVHLKKVGRIKAMVDQGYDPLSRDHHYLFMCL
LMTSSDLSDQSKDFRNSKAIAENIYREFFSQGDLEKQMGASPMEMMDRDRAAVPKIQLDF
MDTVALPVFEMVAELVPEGRSTFEAITLNRQCWAALDEILVERGNRPVLGLDYLRDDELE
KQVLERVNKKKNQQNKT
>A0A4U9DC99|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Raoultella terrigena|TrEMBL
MLLAQISDTHFRSHGQKLYGFIDVNAANADVVSQLNALQERPDAVVISGDIVNCGRPEEY
EAARQILSGLNYPLYLIPGNHDDKALFLEYLHPLCPQLGSDPQNMRYAVDDFATCLLFID
SSRAGTSSGWLTDETIKWLEAQLFDGGDKPATVFMHHPPLPLGNAQMDPIACENGYRLLA
LVERFPSLTRIFCGHNHSLTLTQHRQAIISTVPGTVHQVPYFHEDTRPYYDLSPASCLMH
RQVGELWVSYQHSLAHYAGPWLYDENISCPTQER
>A0A0U1R2M7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)|TrEMBL
MLLKYLSIKSASDKIKSGLLKTGVILSFSLFSSLSTAAFEVVALGVDGGVSDGNLTSYLI
RNDSQPLYLGLDAGSVLPGIARALEKGHFAAITDAMAAPLTRQGYIFRQSINSYFISHAH
LDHVSGLIIGSPDDSKKTIYASADTIDVLRNYYFNWRVWPNFTDSGSGTRLGTYRMQVVR
PAQSLSLGLTRLTGEMYPLSHDKSPSSMLLISSNNEFFAYFGDTGPDDVEKSKNLDTVWR
KLAEKVTQQQLKGMIIEVSYPNDVADNKLFGHMTPTWLLKELKKLEQYSGEGQPLKGLPV
VISHIKPSFQQGQDVRKLILSELQQGNDMGIEFILMEQGDSQKFQ
>A0A143GPQ3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas yamanorum|TrEMBL
MITPWENALPSVSALNPDASALLVQLSDSHLFAEADGGLLGMKTRESLQRVIDTVLVQQP
QIDLVLATGDLSQDGTLESYQAFRDMTRQIEAPARWIPGNHDEPQVMLQAAINSALLEPV
VDVGNWRITLLDSAVPGSVPGYLQDQQLQLLAQSLSEAPTRHHLVCFHHHPVSIGCAWME
PIGLRNPEALFAVLDRFPQVRAVLWGHVHQEIDRERNGVRLLASPSTCIQFAPGSEDFKV
SDEAPGYRWLRLHADGRLETGVERVQGFAFQVDYGSNGY
>A0A378ZLZ6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Paenibacillus thiaminolyticus|TrEMBL
MVAEQSIPRLVFPVISDVHIAPTGEESIHKYEQALRHLNARAPRQDAFVIVGDLTNNGTI
AEYERHMNTLRKHKQGGAELLIAIGNHDYWNDLPAKEAQARFLEMTGMEAMYYHRVIQGY
HFIILATEDKPTHGYFSLDQIEWLKRQLEEAAADAPERPIFVFLHQHLKDTVYGSEEWGI
QENIGELMAALDPYPQVITFSGHSHYPLNDPRSIHQKRFTSVGTASVSYMEVERGKLQGN
LPPGHEKFSQGCLVEVYADKVAIRRLDFAHQREIGEAWVVPVPVTPAAFIYTNERDQEPP
RFPANAEAHVEAELAAWDSITIVFDQAQDNELVHSYRITLKDAETGAEVTRYLAYSEFYL
YPMPEKLQLILAELDPDRTYSIEVRAMDAFGNMSEQALCTHGRTKTVSTLV
>A0A8D9L9S0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Parabacteroides distasonis|TrEMBL
MRIVHISDIHLTENGTEIWGINTLEHFQKAIHKIKEMDGLDGIIVSGDLSNDGSKWTYEC
IDRAFEEIGVPTYCCPGNHDNLEMFYRGYKPYHYKINEKFEICGWDFIMLNSAVPDMSRG
YFNPDVLMRLLKSCDGPVAIVLHHPPVEQDGWLNRKLLDNKSHFKKIIEHFHNVKLVLYG
HSHYASFRTFEDIIYNCSPSIGFAFSPKLPKFEIACGEEGFSLIDTSNDDISINTILI
>A0A1V4SI68|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Ruminiclostridium hungatei|TrEMBL
MSIFAIADLHLALGIDKPMDVFGGRWSNYMEKLKNNWIETVAHTDTVIIPGDVSWATYIE
NVYEDFRYIEALPGKKIISKGNHDYWWTTSSKLNKYLKEKEFTTISFMHNNSFMAENFSI
CGTRGWKCPGEDDFKKEDEKIYNREIERLELSIKSSANQEQSERLVFMHYPPVTAKSQSS
GFIDVMKKHGITRCFYGHLHGDGIKGAIEGEYEGIELKLISADYLNFVPLPIVSR
>A0A1T8DDR3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Mycobacteroides abscessus subsp. massiliense|TrEMBL
MTGEQDPSSMSRRQLIRHTAWFGAAVALTVAGGEVISHVAGSAAAAATTRPTLRFAQISD
SHLGFNGTANANVVDSFGHAINQINNLGYTPDFVIHTGDLTHLATDAQFDQAKQMMSGLS
TPHVFTVPGEHDSIDDAGQKYRSVFGDGTRGDGWYSFDIAGVHVIALVNTLNLKKLGHLG
NDQLEFIEKDLAPVSSDTPIIVFSHIPLFAMYPEWGWGTDDSAQALSYLKRFASVTCLNG
HVHQLFTKTEGNITFYSGTTTAYPLPKPGDGPAPKPVTLPAGQLHDILGIREVSYLRGTQ
PLALKEDKLR
>G2DDF9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|endosymbiont of Riftia pachyptila|TrEMBL
MANCHYDHRLCSDPLEKQNLLHGIFISRLTTLFRKVFLDYYNSYFAEQASKTKPADALAG
DKKLIAMGTEPTNDSKLFDDLPDGAITLLQLSDSHIYADQDRCLVGINTQDSLDQVIALA
RQQLSTPDLLLATGDLVHDASAAGYQRIAERLSAFGCPVYCLPGNHDVPKVMQEHLNRPP
LYCLPSLQRGNWSIIFLDSTIPGKPGGHLDDAQLELLSETLNRHPKHHTLITMHHHPVPV
GSAWMDTMALVNPEPLFHLLEQHSQVRAVLFGHIHQEFDTKHRGIRLIGTPSTCIQFIAG
QDKFGIDSKPPGYRAMVLLESGEIRTEVRLLQALPLGLDLSSGGY
>A0A8H8XHR7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bathymodiolus brooksi thiotrophic gill symbiont|TrEMBL
MHHFIQISDCHIDDTEQSLGVNTHQNLAHIIDKIAPMQSDALLISGDLTHHGTLTSYKKL
KKLLAPIQSNIFVLAGNHDDAHNLATVFPAYLFNKISIGAWEIISVDSVQAKKTSGYLTK
DVLLELDKQLSNSKSKYILVVLHHPIVPMCSTWDDSLSLENPQDLFTILDKYLKIQAVLF
GHAHESAEFERNGLKIIACPSTAVQFTDEKRIGFNHYTLHNNGHLEYKTQWI
>A0A2A2LYX4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Diploscapter pachys|TrEMBL
MRIFRRICDEDDELTDITPEAVPEEVREWLAATFTRQNAGKKREKPKFKRVANAIRTGIF
FDKLFRKQQNVQCPIPQGLDECLKDINHWYFDPFKLNEISEGHALKFVAYQLFNVYGFMD
RFKIPLSAMDNFFHALEIGYLKHNNPYHNVVHAADVTQSSHFMLSQTGLANSLSDMELLA
ILFAAACHDLEHTENHHASASFRLLRDEDKNILQHFSGAEFREFRNTVIEIILATDMSTH
FVQIKTMKNMLSLPEGIDKIKAMCLIVHACDISHPSKPWNLHERWTEGVLEEFFRQGDLE
ASMGLPYSPLCDRHTVHIADSQIGFIDFIVEPTCVVVNELLTKMVEPLVSLPPTDSLFPP
SVDGDQTSPSNALSPLPDLRNSSNSPSSIRKIPLNYCGKLDIPTPWMKYLQENKGFWKIR
AAKEEEERRLKEAEEPKHEGNPEIKQNGVE
>A0A448DL98|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Pseudomonas fluorescens|TrEMBL
MPSVSTLTTADPALLVQLSDSHLFAEADGKLLGMQTRESLQKVIDLVLAQQPQIDLLLAT
GDISQDGTLESYQQFRQLSAQIDAPARWIPGNHDEPQIMAIAAVQSALLEPVVDIGNWRV
TLLDSAVPGSVPGYLQDDQLQLLARSLSEAPERHHLVCFHHHPVSIGCAWMEPIGLRNPE
AFFEVLDRFPQVRAVLWGHVHQEIDRMRNGVRLMASPSTCIQFEPGSADFKVGDQAPGYR
WLRLLPDGGLETGVERVTGFQFTVDYGSNGY
>A0A086PRP5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii VAND|TrEMBL
MWFYSYLRHPNDVPSLCTHIRSSNIFLRLGPQYYLPEDERKSLFVRTCHLLYYLASLLFL
TTLTTYTAIKIPSSPSTTTELLSQLFPFNSIDDCNERLSCKVDCVLYAFPDLNCAKDDGS
LLTFGGNSYSSLYFYHYPGKDVPLQKEARTAWERCYQIMRETTGRLQFLQQDRETVERTH
TCFAGCKTNGAVTFTQKLTDGTPVVFDSGTDWLQMAPAGSLPQDTRPACNPSEPPSLLCV
EPTDECQHVTLRYQVCIGDTAFCFDIVRILITIALGVVWNVVLDAFVVWAMSIDDSDPQN
LGRVASKCGLQIIATAIIVSSFFCLVASMTRILSMDANIARHGTLWTSFVLVIIIDQLFS
FLFSVLIWYAMLRRCGRQLPDESRFQYKIHPSPVLVKLKKATRKIVNYNGFEMFFTMLLG
WMVVDLTCRMILCQFFFDETAFLNQADRILEVVDFIILILFIVEICLRIAADGLKIYFSD
PINCIDFFLVFFGFGIRIVDFFIQINKGIGNVLFIMRLVRLYRLHRPPTGSLAIGKKEVF
TSRVERIIAVLNKALEIEELTTREKDSLKWLIQTISSGKLYEMGSEEKKKTDSHVQAWIS
IISTQSQSANQMADDMENILLERVKQMTKAGDAETDMPAVLQLEYGIDVSLDHAIEGYLA
NNLITWNFDVFRFHVIAGRAALPKLFVRCLQHQEVCSLFNLKIENMLRFAMELEKTSFST
TPFHNSIRSAEVLQAMHLFLAFFDTQIKGFFNSREILAALLAAVVWDYQHPGFSSAFLIK
TQHAIAIRYNDRNVLEHHHVAAAFSLMQKLGENDPLLAFPEDQYIALRKIIIQLSQSGSR
SNQTACLSLLKTKLQQAEFPRSITEDKNIILCNLMNAANYSFLGRPLQLYLQWSQKYMEE
LFMQGDRELELDMPITKNCDRHTTSEAVVQLGLIDGWAIPIYTTLAQTVPKLNAIVVSHL
RRNRLHWLDEQQEEDKSKEKQTKVTPIKRYSKTKQGSTEATGNGELSKPEATTIEIADGT
AGVPELRANANPLSEVD
>A0A086QFG8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Toxoplasma gondii VAND|TrEMBL
MKVSPHRTSERGSSPTGGENGKHRFTQSGALRRQSAAPGGAKRSTMTGFLKAEPNPGSET
QDLEATQRRLKSAHRRTMLPTWILTGLSLAYVLFEGGRLLYETTLQQWSEEAILHIDKEI
FFLHDFAAGFYSLAEQLTSDYCFLNFMNAHSPPAAPTSTREEVQNLISGYAPSFCSWIKD
LYFFEEPLADTADRSTYQLLNTTYICGERFADLVQRINGNMVEVVQNYTLVKMRLIEMLA
PLVDNRNWSPHLLCDLDFSAGDLWACHDGLTALEQLRGQLSGYLGREWHLYSPILSIVIV
FILATLFFSRRHAFNAVFHTRFESLWAMLQQIDQVRKQ
>A0A447T7C3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Chromobacterium violaceum|TrEMBL
MKAGQKMRIAQLTDLHLFADRQGRLLGRDTHAALDRVLAALRTAEGVEAVLLTGDVSQDE
SEASYHLAAEALAALGVPVHWIAGNHDDRAAMARVFAGYTFLRPLETLALGGWTFIGVDS
CVAGQDGGRLSDAGLDRLRRLLDEAGDGRPPWCCTTTRWRWARPCWTTACWRRPRRSGGS
RRHRPR
>A0A0M7IWI0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Achromobacter aegrifaciens|TrEMBL
MARIHSLTRRDDAPAMLVQLTDSHLFGEPETSMLGVNTDASLRAVLRQIEADGKHPDLLL
ATGDMSQDGEAAAYRRLARVLSEAPALAQASIRCLPGNHDLPAVMRQELPQWSVPVTDVG
AWRVVALDTTVPGSNAGHLPASQLDLLEAALAEAPGRHTLIAMHHNPMQIDSHWHDSMMI
DNPQALFKLLTRWPQVRVLLWGHVHHEFDRRRHNLRMLATPSTCFQFSIRDGKHVVDNMA
PGYRWIKLYQDGSMATGVRRVQDALWHGARTAADNAQAA
>A0A1V4IKV6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Clostridium oryzae|TrEMBL
MKKGILKKLLTAFIVTATFSTVLMFPQPVKAEEISKPLLTFPVISDVHIGGTNADSKFQN
ALQDLKANFPNYNAIATVGDLTDAGTPDEYDTFMSILNANKVKNAQTFITMGNHEYYAGD
TDNTGYQQRFLSKTGMPALNYDKWINGYHFIILSPENLGTGGSGVIVTQNQLKWLDKMLN
ENQTSDKPAFVFLHQPMMHTTYGSDLDDNVENSDELMAVLKKHPKAMYFSGHSHYLLEHP
RTMYQDGFTMFNTGAIYYMMSEGDAYEDSSIAEGLVVQVYKDKVVVKCREFSQHKWVGQT
YTVNYPFKQSPKDLESPYWNTDSKASATNISKHSAEISWLKAFDNTLVTSYKVINKTTGA
STSVVNSLLTPEPSTHTFKLTGLKASTKYSYEIQAEDAFNNDSAKTLTVDFTTADGGPQD
NDPNGPDLLNIDFSSGTAADDSIYCNDGTLEGNAKIAYDKDFKKNVLVLDGVNSDVRIPY
SDSFKNMSNSFTWITAFSLNTVDGCQDVLGRTQGSDVCYELNDKKMELWAHINGTYYTLR
STELSPNTIYHLTATYDGQKLCYYLNGKLVDSLNITGAVDINSNIDCTIGADPESNHTAR
SYFNGKIDFVNMYTRALSSDEITALYNKYHLQLQQ
>A0A2P4T5X0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bambusicola thoracicus|TrEMBL
NFYSSFCRRLLDTEDELSDIQSDSVPLEVRDWLASTFTREMGIVKRRPEEKPKFRSIVHA
VQAGIFVERMYRRTSSMVGLAYPAEVIVTFKDVDKWSFDVFALNEASGEHSLKFMMYELF
TRYDLLNRFKIPVPNLITFAETLEVGYSKYKNPYHNLIHAADVTQTVHYIMIHTGIMHWL
TELEILAMIFAAAIHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEE
MNILANLTKDDWRELRSLVIEMVLSTDMSGHFQQIKTMRHTLQQAEG
>A0A4P8IFC8|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Anaerostipes rhamnosivorans|TrEMBL
MKIIQISDFHLRGDGKLSFQKADTIAALNKTIAYFCSLKEYELPEYFVVTGDLADGGTRE
GYEIIREKIHQLPRPCYIVPGNHDKRDFFLEMFPAETPVKEDIKPYICYTLDDDPIRTIV
LDTSKPGCHSGGMTDKAAQWLETKITEYPDKPTLVFTHHPPFVTGLPAMDEGFDQADRLA
EILKKHKNVRLCCGHMHTSIFTMWNGIPCVTCPSVSMQMEVDFRRKDGPDVTPDELKDNF
KGGGDRFFLGNPAYLIHDLQGDTINTHYVTIPAEADYSGPWPFKYYDGEGH
>A0A3P7IXY0|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Strongylus vulgaris|TrEMBL
MEGKLWKVADALSCNEDILHRWLCTIEAHYHAGNAYHNATHAADVLQATSYFLDSPAVAA
HISENHAIAAILAATVHDLDHPGRGNAFLINTRQSLAVLYNDHSVLENHHVALAFQLTLQ
QSNNVNIFSNLSREEFTSMRHAMVEMVLATDISRHFEYLVKFNKMNVVDVPDDAREGNSM
TICNMLVKCADISNPTREWSLCQKWAYRIVEEYFDQVSNRAKIVHIQRFNILLCCQK
>C7DXW3|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cavia porcellus|TrEMBL
TTTTSATGLPTLEPAPVRRDRSASIKLHEAPSSSTVNPDSWNSSVMMTLTKSRSFTSSYA
VSAANHVKAKKQNRPGALAKISPLQSPCSSPLQGTPASSPISKISALQFPESAETTAKHG
PSSHRTLTYTQSAPDLSPQILDPPVICSSCGRPYSQATPADGPLEKSGEATQTSSRTDDT
AQVTSDYETNNNSDS
>C7DXW4|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cavia porcellus|TrEMBL
PMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRP
LTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLS
TP
>C7DXW5|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cavia porcellus|TrEMBL
NQCNGFCRACEKAGFKCTVTKEAQAVLACFLDKHHDIIIIDHRNPGQLDAEALCRSIRSS
KLSENTVIVGVVRRVDKEELSVMPFIAAGFTRRYVENPSIMACYNELLQLEFGEVRSQLK
LRACNSVFTALEKSQEAIEITSEDHIIQYAN
>C7DXW6|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cavia porcellus|TrEMBL
MAGKPVLHYFDGRGRMESTRWLLAAAGIEFEEKFVTCPEDLEKLRKDGVLMFQQVPMVEM
DGMKLVQSRAILNYIANKYNLYGKDTKERLLIDMYTEGMADLNELISSLIITPPDQKESK
MNLIRDRTKNRYLPAFEK
>C7DXW7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Cavia porcellus|TrEMBL
LHDNYRNNPFHNFRHCFCVTQMMYSMVWLCNLQEKFSQMDILVLMTAAICHDLDHPGYNN
TYQINARTELAVRYNDISPLENHHCAVAFQILARPECNIFANVPTEGFRQIRQGMITLIL
ATDMARHEEIMDSFKEKMENFDYSNDEHLTLLKMILIKCCDISNEVRPVDVAEPWVDCLL
EQYFMQSDREKSEGLPVAP
>P0A8Z7|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Escherichia coli (strain K12)|Swiss-Prot
MSTLLYLHGFNSSPRSAKASLLKNWLAEHHPDVEMIIPQLPPYPSDAAELLESIVLEHGG
DSLGIVGSSLGGYYATWLSQCFMLPAVVVNPAVRPFELLTDYLGQNENPYTGQQYVLESR
HIYDLKVMQIDPLEAPDLIWLLQQTGDEVLDYRQAVAYYASCRQTVIEGGNHAFTGFEDY
FNPIVDFLGLHHL
>P27815|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Homo sapiens|Swiss-Prot
MEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAERERQ
PHRPIERADAMDTSDRPGLRTTRMSWPSSFHGTGTGSGGAGGGSSRRFEAENGPTPSPGR
SPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
FAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
PSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTD
QEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYML
TLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEE
ISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAELEAVYLT
QQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLP
STAAEVEAQREHQAAKRACSACAGTFGEDTSALPAPGGGGSGGDPT
>Q9HCR9|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Homo sapiens|Swiss-Prot
MAASRLDFGEVETFLDRHPELFEDYLMRKGKQEMVEKWLQRHSQGQGALGPRPSLAGTSS
LAHSTCRGGSSVGGGTGPNGSAHSQPLPGGGDCGGVPLSPSWAGGSRGDGNLQRRASQKE
LRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRV
NLPRYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSL
FLVEGAAAGKKTLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIP
DAYQDRRFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQ
MYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKC
ERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESMEKSSYSDWLINNSIAELVA
STGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFD
DADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANI
PLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRM
VLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSG
SALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLY
FERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFE
QGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVAT
NRSKWEELHQKRLLASTASSSPASVMVAKEDRN
>Q9X1T1|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)|TrEMBL
MDEIVKVLSQHDRILVVGHIMPDGDCVSSVLSLTLGLEKLGKEVKAAVDYKIPYVFEKFP
YIDKIEENPNFDPELLVVVDASSPDRIGKFQDLLDKVPSVVIDHHSTNTNFGNWNWVDPS
FAATAQMIFRINKALGVEYDSNLATLNYLGIATDTGFFRHSNADVRVFEDAYKLVKMGAD
AHFVAKEILENKRFEQFKLFAEVLERLQLLENGKIAYSYIDYDTYLRHNCTDEDSAGFVG
ELRSIRGVEVAVLFMEFPRGKIHVSMRSKDWFNVNEVAFELGGGGHPRAAGVTFEGKKIE
EVIPRVINHLLKKFKEGVESESEKIPEGDVLGG
>Q07343|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Homo sapiens|Swiss-Prot
MKKSRSVMTVMADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQS
ERARTPEGDGISRPTTLPLTTLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSAGLVL
HATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVR
NNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKK
KQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSH
NRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHV
LLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS
SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI
SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQSP
SPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLG
ETDIDIATEDKSPVDT
>Q08499|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Homo sapiens|Swiss-Prot
MEAEGSSAPARAGSGEGSDSAGGATLKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPP
PPPSPQPQPQCPLQPPPPPPLPPPPPPPGAARGRYASSGATGRVRHRGYSDTERYLYCRA
MDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLDPMTSPGSGLILQA
NFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNF
AALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSV
SEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRP
MSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPL
TVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLST
PALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGF
KLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVL
LLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMC
DKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAP
DDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPL
DEQVEEEAVGEEEESQPEACVIDDRSPDT
>P54748|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Rattus norvegicus|Swiss-Prot
MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYPDSAERSETERS
PHRPIERADAVDTGDRPGLRTTRMSWPSSFHGTGTGGGSSRRLEAENGPTPSPGRSPLDS
QASPGLVLHAGATTSQRRESFLYRSDSDYDMSPKAVSRSSSVASEAHAEDLIVTPFAQVL
ASLRSVRSNFSLLTNVPIPSNKRSPLGGPPSVCKATLSEETCQQLARETLEELDWCLEQL
ETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNEVEIPSPTP
RQRAFQQPPPSVLRQSQPMSQITGLKKLVHTGSLNTNVPRFGVKTDQEDLLAQELENLSK
WGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFHIPVDTMMMYMLTLEDHYHADVAYHN
SLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELAL
MYNDESVLENHHLAVGFKLLQEENCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLA
DLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFF
QQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLED
NRDWYHSAIRQSPSPPLEEEPGGLGHPSLPDKFQFELTLEEEEEEDSLEVPGLPTTEETF
LAAEDARAQAVDWSKVKGPSTTVVEVAERLKQETASAYGAPQESMEAVGCSFSPGTPILP
DVRTLSSSEEAPGLLGLPSTAAEVEAPRDHLAATRACSACSGTSGDNSAIISAPGRWGSG
GDPA
>O76074|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Homo sapiens|Swiss-Prot
MERAGPSFGQQRQQQQPQQQKQQQRDQDSVEAWLDDHWDFTFSYFVRKATREMVNAWFAE
RVHTIPVCKEGIRGHTESCSCPLQQSPRADNSAPGTPTRKISASEFDRPLRPIVVKDSEG
TVSFLSDSEKKEQMPLTPPRFDHDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLI
SADRYSLFLVCEDSSNDKFLISRLFDVAEGSTLEEVSNNCIRLEWNKGIVGHVAALGEPL
NIKDAYEDPRFNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDE
KDFAAYLAFCGIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIIS
FMQVQKCTIFIVDEDCSDSFSSVFHMECEELEKSSDTLTREHDANKINYMYAQYVKNTME
PLNIPDVSKDKRFPWTTENTGNVNQQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEENTGK
VKPFNRNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETREL
QSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWIL
SVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGV
NNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAI
LATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAE
LVATEFFDQGDRERKELNIEPTDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCF
PLLDGCRKNRQKWQALAEQQEKMLINGESGQAKRN
>P04972|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Bos taurus|Swiss-Prot
MNLEPPKAEIRSATRVMGGPVTPRKGPPKFKQRQTRQFKSKPPKKGVQGFGDDIPGMEGL
GTDITVICPWEAFNHLELHELAQYGII
>O60658|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Homo sapiens|Swiss-Prot
MGCAPSIHISERLVAEDAPSPAAPPLSSGGPRLPQGQKTAALPRTRGAGLLESELRDGSG
KKVAVADVQFGPMRFHQDQLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTKEAQAVLACF
LDKHHDIIIIDHRNPRQLDAEALCRSIRSSKLSENTVIVGVVRRVDREELSVMPFISAGF
TRRYVENPNIMACYNELLQLEFGEVRSQLKLRACNSVFTALENSEDAIEITSEDRFIQYA
NPAFETTMGYQSGELIGKELGEVPINEKKADLLDTINSCIRIGKEWQGIYYAKKKNGDNI
QQNVKIIPVIGQGGKIRHYVSIIRVCNGNNKAEKISECVQSDTHTDNQTGKHKDRRKGSL
DVKAVASRATEVSSQRRHSSMARIHSMTIEAPITKVINIINAAQESSPMPVTEALDRVLE
ILRTTELYSPQFGAKDDDPHANDLVGGLMSDGLRRLSGNEYVLSTKNTQMVSSNIITPIS
LDDVPPRIARAMENEEYWDFDIFELEAATHNRPLIYLGLKMFARFGICEFLHCSESTLRS
WLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIHDVDH
PGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQG
IIDMVLATEMTKHFEHVNKFVNSINKPLATLEENGETDKNQEVINTMLRTPENRTLIKRM
LIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQGLPVVMPVFDRNTCSIPKSQIS
FIDYFITDMFDAWDAFVDLPDLMQHLDNNFKYWKGLDEMKLRNLRPPPE
>P18545|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Homo sapiens|Swiss-Prot
MNLEPPKAEFRSATRVAGGPVTPRKGPPKFKQRQTRQFKSKPPKKGVQGFGDDIPGMEGL
GTDITVICPWEAFNHLELHELAQYGII
>Q53I60|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Trypanosoma cruzi|TrEMBL
MSEDAGLPVPRSQWVERSVSCATCGKRFSLFTAKSNCPCCGKLCCSDCVQAECAIVGGSA
PSKVCIDCFSMLQSRRRVEPDEGSSFREFNAASAFPLQTRLLADGRVESGETSRVSPPND
GRVQHFSRANGYSNSLPVLDEYVDDLLRKSELLRMENDVLLNRLREQEAEIQALRLERDR
AVARIVPDGGSMAGRSGTPQVSDEIVKELREELAVAHLRIESVEGELKNALDRAKSSETV
VKNLKQHLCNYKEEVVRLLQSREEVEMLPGVSGHRDMISTRRLPPSIVQDTILAVVPPKS
CAAIGTDVDLRDWGFDTFEVASRVPSVLQSVAMHVALAWDFFASQEEAQKWAFLVAAVEN
NYRPNPYHNAIHAADVLQGTFSLVSAAKPLMEHLTPLECKAAAFAALTHDVCHPGRTNAF
LAAVQDPVSFKFSGKGTLEQLHTATAFELLNVTEFDFTSSMDNASFLEFKNIVSHLIGHT
DMSLHSETVAKHGAKLSAGGFDCTCKEDRLEALSLLLHAADIGASSRGVAIARKWLVILQ
EFADQAEDERRRGLPVTPGFETPSSVEKSQIPFLDFFVIPTFDLLHQLFPSIEEPLHNLR
KLRELYAAKAGVTTPFPPPVDYRSREEKIRSLEAELAYFRRREEEFHRQLLELRTASENV
NKNSAALMTSEGALNKQSQLVCRGEGNMNADWADAGGGFRNEKDVRDLQDVSMDHLVSSK
TVEPDTGDSRPRSRRGSKAETTKAYERNLGEREAALMATARLMENREKRLAVLSEKLAEI
AEGLHEERKRLKPMEEFKTPCFSRETELISEESASMDVTHRFSTQWEAEGRLARKYRELD
ELLLIVRAMRMGYAARRNTHLGWKALSATLAEREAAITEAVELSRQRRRHLEEGRGLHPT
ATQLDRLENAIFQLMSATTLLTQC
>Q13946|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Homo sapiens|Swiss-Prot
MEVCYQLPVLPLDRPVPQHVLSRRGAISFSSSSALFGCPNPRQLSQRRGAISYDSSDQTA
LYIRMLGDVRVRSRAGFESERRGSHPYIDFRIFHSQSEIEVSVSARNIRRLLSFQRYLRS
SRFFRGTAVSNSLNILDDDYNGQAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSL
HGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPW
DILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFS
HLPLESRQQMETQIGALILATDISRQNEYLSLFRSHLDRGDLCLEDTRHRHLVLQMALKC
ADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRHTESIANIQIGFMTYL
VEPLFTEWARFSNTRLSQTMLGHVGLNKASWKGLQREQSSSEDTDAAFELNSQLLPQENR
LS
>Q6S996|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Leishmania major|TrEMBL
MHSAVFSPDAPYCGAAGSNHLCEAVALCQSILARYRRTGTSFSSTELKAIQALRTEFPDT
AQEPAANSAASPDQTTKDFLSILDDATDVPHNPQNDIVAFVEECCDNTKEPTVLFAAINE
RISAVTCSRNVRTYMVIANDNLLWDPVNGVAALIDDVTPLGKCAQARNMLTIANTLYIPL
WFRSELVGCVEVPGACIPRDKATCAQLLLRCVTVAVRNSINISIRKREANKIEAMVGMAT
RLARDTLEESVLVQSIINTAKTLTESDRCSIFLVKADGSLEAHFEDGNVVVLPAGTGIAG
HVAESGAVVNIPNAYEDDRFHRSVDKVTGYHTRTILCLPIAFEGTIVAVAQLINKLDMVT
QSGQRLPRVFGRRDEELFETFSMFAAASLRNCRINETLLKEKKKSDAILDVVALLSNTDI
RDVDSIVRHVLHGAKKLLNADRSSMFLLDKERNELYSKMADSANEIRFPCGQGIAGTVAE
SGVGENIMDAYADSRFNSAVDRQLGYRTQSILCEPITLNGEVLAVVQLVNKLGDDGSVTC
FTPMDRETFQVFSLFAGISINNSHLLEFAVNAGREAMTLSLQRNSITAQRAPKSVKVIAV
TPEEREAVMSIDFGGAYDFTSPGFNLFEVREKYSEPMDAAAGVVYNLLWNSGLPEKFGCR
EQTLLNFILQCRRRYRRVPYHNFYHVVDVCQTLHTYLYTGKASELLTELECYVLLVTALV
HDLDHMGVNNSFYLKTDSPLGILSSASGNNSVLEVHHCSLAIEILSDPAADVFEGLSGQD
VAYAYRALIDCVLATDMAKHADALSRFTELATSGFEKDNDTHRRLVMETLIKAGDVSNVT
KPFETSRMWAMAVTEEFYRQGDMEKEKGVEVLPMFDRSKNNELARGQIGFIDFVAGKFFR
DIVGNLFHGMQWCVDTVNSNRAKWQEILDGRRDSIRSSIV
>O43924|3',5'-cyclic-nucleotide phosphodiesterase|EC 3.1.4.17|Homo sapiens|Swiss-Prot
MSAKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVS
RELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPA
SVLTGNVIIETKFFDDDLLVSTSRVRLFYV