>O29544|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)|Swiss-Prot
MVVKVGVLKMGAIGTALLVEYLLDERADREDIEVRVVTSGAKMQPEEAVVAEKLKEFDPD
VVIVVSPNAALPGPKAAREAFEGKPVIVISDAPAKKAKDELKEKGFGYILINADSMIGAR
REFLDPTEMALFNADVVKVLAATGAFRLVQEAIDKVIEDIKAGKQPELPQIVVTAEKAVE
AGKFSNPYAKAKAMAAFYIAEKVADIDVKGCFIEKDPEKYIPLVASAHEMMRIAAILADQ
AREIEKSNDTVFRNPHAKDGKILGKTQLMAKPE
>A6UWS1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)|Swiss-Prot
MVVKIGIIKCGNIGMSPLIDLALDERADRTNIDVISIGSGAKMGPNQVVEVTTKMVEDIK
PDFIIYVGPNPAAPGPAKAREILSASDIPSVIIGDAPGIKAKDKMAEEGLGYILIKCDPM
IGARRQFLDPVEMAMFNADVIRVLAGTGAARVVQNAIDDIVEAIEAGNEIELPKIVVTDA
KSVAAAEFSNPYAKAKAMAAFAMAEQVANIDVKGCFMTKEMEKYIPIVASAHEMIRTAAK
LVDEARELEKATDSVSRKPHGADGKRLNKTKLMEKPE
>Q8THT2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)|Swiss-Prot
MRKMVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMGPADAADTESFKQWN
ADFVVMISPNAAAPGPTAAREIWKDVPCIVVSDGPTKKEAREALEQEGFGYIILPVDPLI
GAKREFLDPVEMASFNSDAMKVLSSCGVVRLIQEELDRVTEQVASGKSGEDLELPHIFAK
PEKCVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEVEQVCLTAAAGHEIMGAA
AILATQAREIEKSNDTVFRQPHAKNGTLLKKVKLYEKPE
>A7I5N7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8)|Swiss-Prot
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVSNMKAWKP
DFAIVVSPNGVLPGPTGAREQLAAAGIPVIIITDDVTTKKEWEEVKNSKFGYIIMKADSM
IGARREFLDPIEMADFNGNLVKVLAITGAFRKLQLALDKVIDQVKAGKKGTEIELPKIVM
TTDKAVDGEFTNDYALAKARAAHEIAIAVAGQNVKGCFMTKEWEKYIPIVASAHEMMRIA
AVLCDEAREIEKAGDGILRQPHKKDGVLVRKTKLVAKFE
>Q2FU89|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)|Swiss-Prot
MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVTNMKAWGP
DFCIVVSPNGVLPGPKGAREALAAAGIPCVVITDDITTKKEEWEALKASEFGYVIMKGDS
MIGARREFLDPIEMADYNGNLIKVLSITGAFRKLQVALDEVIDQVKAGKKGKDLALPKLV
MTSDKAVEGEFSNPYAYAKARAAYEIAQAVAGVNVKGCFMTKGFENYTPIVASAHEMMRQ
AMLLCEEAREMEKATDAVIRKPHKNDGTRVAKKTLISKPE
>Q58441|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)|Swiss-Prot
MVVKIGIIKCGNIGMSPVVDLALDERADRKDIAVRVLGSGAKMDPESVEEVTKKMVEEVK
PDFIIYIGPNPAAPGPKKAREILSQSGIPAVIIGDAPGLRVKDEMEQQGLGYIIIKCDPM
IGARREFLDPVEMALFNADVIRVLAGTGALRIVQEAIDKMIDAVKEGKEIELPKIVITEQ
KAVEAMEFTNPYAKAKAMAAFTIAEKVGDVDVKGCFMTKEAEKYIPIVASAHEMIRYAAK
LVDEARELEKAMDAVSRKPHHPEGKRLSKKALMEKPE
>P94951|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)|Swiss-Prot
MTVAKAIFIKCGNLGTSMMMDMLLDERADREDVEFRVVGTSVKMDPECVEAAVEMALDIA
EDFEPDFIVYGGPNPAAPGPSKAREMLADSEYPAVIIGDAPGLKVKDEMEEQGLGYILVK
PDAMLGARREFLDPVEMAIYNADLMKVLAATGVFRVVQEAFDELIEKAKEDEISENDLPK
LVIDRNTLLEREEFENPYAMVKAMAALEIAENVADVSVEGCFVEQDKERYVPIVASAHEM
MRKAAELADEARELEKSNDAVLRTPHAPDGKVLSKRKFMEDPE
>A2SPK1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)|Swiss-Prot
MVVKVGVAKLGNIAAGVMAELLLDERADREDMMTFMATSGTKLQKEDVDRVVSNLKAWQP
DFAIVVSPNGVLEGPVGAREDLKAAGIPTIVITDDVTTKKEGWEALKASGFGYIIVKADA
MIGARREFLDPVEMADYNGNLVKVLALTGAFRKLQLELDKVIDQVKAGKKGAELELPKLV
LNSDNSTKGEFTNPYALAKARAAYEIAQAVAGVNVKGCFMTKEWTDYVPIVASAHEMMRA
AANLCDQARELEKGCDGVIRKPHKKTGEIVSKVALISKPE
>A4FZG7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcus maripaludis (strain C5 / ATCC BAA-1333)|Swiss-Prot
MVVKIGILKCGNIGMSPVVDLCLDERADRNDIDVRVLGSGAKMNPDQVEEVAKKMVEEVK
PDFIVYIGPNPAAPGPKKAREILSAGGIPAVIIGDAPGIKDKDAMAEEGLGYVLIKCDPM
IGARRQFLDPVEMAMFNADVIRVLAGTGALRVVQNAIDDMVFAVEEGKEIPLPKIVITEQ
KAVEAMDFANPYAKAKAMAAFVMAEKVADIDVKGCFMTKEMEKYIPIVASAHETIRYAAK
LVDEARELEKATDAVSRKPHAGAGQILNKCKLMEKPE
>A6VJ05|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcus maripaludis (strain C7 / ATCC BAA-1331)|Swiss-Prot
MVVKIGILKCGNIGMSPVVDLCLDERADRNDIDVRVLGSGAKMGPEQVEEVAKKMVEEVK
PDFIVYIGPNPAAPGPKKAREILSAGGIPTVIIGDAPGIKDKDAMAEEGLGYVLIKCDPM
IGARRQFLDPVEMAMFNADVIRVLAGTGALRVVQNAIDDMVFAVEEGKEIPLPKIVITEQ
KAVDAMDFANPYAKAKAMAAFVMAEKVADIDVKGCFMTKEMEKYIPIVASAHEAIRYAAK
LVDEARELEKATDAVSRKPHAGEGKILNKCKLMAKPE
>Q8PXV8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)|Swiss-Prot
MKKMVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMAPADAADTESFKQWN
ADFVVIISPNAAAPGPTAAREIWKDVPCIIVSDGPTKKEAREAFEQEGFGYIILPVDPLI
GAKREFLDSVEMASFNADAMKVLSICGVVRLIQEELDKVTEQVASGKSGKDLELPHIFAK
PEKCVEHAGFANPYAKSKALAALHMAEKVAQVNFPACFMLKEIEQVCLTAAAGHEIMGAA
AQLANQAREIEKSNDTVSRMPHAKNGAVLKKVRLYEKPE
>A3CSZ5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)|Swiss-Prot
MVVKVGIAKLGNIASGVMGELLLDERADREDMITFMATSGTKLQPEDIERVVSNMKAWGP
DFCIVVSPNGVLPGPTQAREDLAAAGIPCIVITDDVTTKKEQFEALKASNFGYIIMKADA
MIGARREFLDPIEMADYNGNLVKVLALTGAFRKMQMELDKVIDQVKAGKKGADLALPKVV
MTSDKAVDGEFSNPYALAKARAAYEIAQSVAGVNVKGCFMTKEWEKYIPIVASAHEMMRQ
AMLLCEEARTLEKGVDAVIRKPHKKTGEIVSKTALISKPE
>Q6M099|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcus maripaludis (strain S2 / LL)|Swiss-Prot
MVVKIGILKCGNIGMSPVVDLCLDERADRNDIDVRVLGSGAKMGPEQVEEVAKKMVEEIK
PDFIVYIGPNPAAPGPKKAREILSAGGIPAVIIGDAPGIKDKDAMAEEGLGYVLIKCDPM
IGARRQFLDPVEMAMFNADVIRVLAGTGALRVVQNAIDDMVFAVEEGKEIPLPKIVITEQ
KAVEAMDFANPYAKAKAMAAFVMAEKVADIDVKGCFMTKEMEKYIPIVASAHETIRYAAK
LVDEARELEKATDAVSRKPHAGAGKILNKCKLMEKPE
>B8GJQ7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)|Swiss-Prot
MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVSTMKAWEP
DFCIVVSPNGVLPGPVGARDELLKAGIPCVVITDDITTKKEGWEALKASSFGYIIMKADA
MIGARREFLDPVEMADFNGNLVKVLALTGAFRKLQTELDKVIDQVKEGKKGADLVLPKVV
MTSDKAVDGEFSNPYALAKARAAYEIAQAVAGVNVKGCFMTKEWEKYIPIVASAHEMMRQ
AAALGDEAREIEKAGNGIIRKPHKKDGTIVSKITLISKPE
>A5UMI1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)|Swiss-Prot
MVVKIGIIKSGNIGTSPVLDLLLDERADRPNIDVRVFGSGAKMNPEQVEDVVPKVDQFDP
DFCIFISPNPGAPGPAKARELLSEKDIPAIIIGDAPGKGKKDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNADILKVLAETGALRLVQNTIDGVIDGAAAGNIELPKLIITAEKA
VEAAGFENPYAKAKAIAAYEMAGAVANLDMKGCFMTKGFENFIPLVAAAHEMAASAAALA
DEAREIEKGNDSVLRTPHMKEGNTGCKTDLISKPE
>Q2NHQ2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)|Swiss-Prot
MVVKIGIVKVGNIGTSVLIDMILDERADREDIDVRTISSGAKMGKNQMDDVLPKIDEYNP
DVIIFISPDPGAKSPSSARETLSKKNIPTIVIGDGPGERAIGSMKEQGLGYIIVKADSMI
GARREFLDATEMAVFNSDVLMVLSTTGVFRLIHKTLDKVIRDIDEDKLYSLPELVITAEN
AVDAADFKNPYAKSKAIAAYSIACQVSSMNVRACFKTKDYHVYIPLVSAAHEMMSAASKL
AYEAREIEKSNDTVVRTAHRRNGSILYGTSLNDNKE
>Q50501|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)|Swiss-Prot
MVVKIGIIRCGNIGTSPVLDLLLDERADRPNIDVCVVGSGAKMNPDEIERAVPTMLEMDR
DFVIFISPNPGAPGPAKARELLSEADVPAMIIGDAPGLRVKDEIEEQGLGYIIVKADPMI
GARREFLDPTEMASFNSDVIKVLAFTGAYRVVQNTIDAMIADVEAGKAPELPQVVIDTDV
AVEAAGYENPYAKAKAMAAYEIATKVADIDVKGCFMVQDPDKYIPIVASAHEMLAAAAKL
AVEAREIEKANDTVLRTPHGKEGETLSKTDLLAKPE
>P55300|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg)|Swiss-Prot
MVVKIGIIKCGNIGTSPVLDLLLDERADRPNIDVCVVGSGAKMNPDEIERAVPTMLEMER
DFVIFISPNPGAPGPAKARELLSAADVPAMIIGDAPGLRVKDEIEEQGLGYIIVKADPMI
GARREFLDPTEMASFNSDVIKVLAFTGAYRVVQNTIDAMIADVEAGKAPELPQVVIDTDK
AVEAAGYTNPYAKAKAMAAYEIATKVADIDVRGCFMVQDPDQYIPIVASAHEMLSAAAKL
AIEAREIEKANDTVLRTPHGKEGKTLSKKDLLAKPE
>A6URY5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)|Swiss-Prot
MVVKIGILKCGNIGMSPIIDLCLDERADRNDIDVRVLGSGAKMNPDQVEEVSKKMVEEKP
DFIVYIGPNPAAPGPKKAREILAASGIPSVIIGDAPGIKDKDAMAEQGLGYVLIKCDPMI
GARRQFLDPVEMAMFNADVIRVLAGTGALRVVQNAIDEMVFAVEEGKEISLPKIVITEQK
AVDAMDFANPYAKAKAMAAFVMAEKTADIDVKGCFMTKEMEKYIPIVASAHETIRYAAKM
VDEARELEKATDAVSRKPHAGDGKILNKCKLMEKPE
>A0A285EQL2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanohalophilus euhalobius|TrEMBL
MVKVGFIKLGNLGMSQVIDLVQDEIAAREGISTRVFGTGPKMDKETAASTDELKAWEPDF
VVMISPNASAPGPKSARELWNDYPCIVVSDGPTKKDDRQALEDAGFGYIIMTVDPLIGAK
TEFLDAVEMASFNSDAMKVLSTCGVVRLLQEELDAVTAQVDEGKSGADLELPHILAKPQK
CIERAGFNNPYAKAKGLAALHMASKVAEVNMPACFILKEIEDVALTAAAGHELMRAAAQL
AIEAREIEKANDSVFRQPHSKKGAQLQKIKLYEKPQKV
>A0A2H4VS60|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium subterraneum|TrEMBL
MVVKIGVIKCGNIGTSPVLDLVLDERADRPNIDVRGVSSGAKMNPEQIEEVVPKIMDFDP
DFVIFISPNPGAPGPAKARELLSGMDVPALIIGDAPGMGKREEMDEQELGYIVVLGDPMI
GARREFLDPTEMASFNADVIKVLAATGAYRVVQETIDGMIAAAEAGEAIELPKVVIDAAK
ATETAGFASPYAKAKAMAAYEMAAKVGDIDLKGCFMVKEMEKYVPIVASAHELIATAAKL
ATEAREIEKANDTVLRKPHGPQGQTLSKTVLVSKPE
>A0A1L3Q4K4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanohalophilus halophilus|TrEMBL
MVKVGFIKLGNLGMSQVIDLVQDEIAAREGISTRVFGTGPKMDKETAASTEELKAWDPDF
VVMISPNASAPGPKSARELWNDYPCIVVSDGPTKKDDRQALEDAGFGYIIMTVDPLIGAK
TEFLDAVEMASFNSDAMKVLSTCGVVRLLQEELDAVTAQVDEGKSGADLELPHILAKPQK
CIERAGFNNPYAKAKGLAALHMASKVAEVNMPACFILKEIEDVALTAATGHELMRAAAQL
AIEAREIEKANDSVFRQPHSKKGVQLQKTKLYEKPQKV
>A0A1I4TIS8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanolobus profundi|TrEMBL
MAKIGFIKLGNLGMSQVVDLVQDEIAAREGITVRSFGTGPKMGKDEAAATEELKKFDADF
YVMISPNSSAPGPTAAREIYKDVPCIVISDGPTKKDDRAALEEAGFGYIIMTVDPLIGAK
TEFLDPVEMASFNSDAMKVLSTCGVVRLIQEELDKVAAMADEGKELELPHILAKPEKCIE
RAGFNNPYAKAKGLAALHMADMVAKINFPACFMMKEIEQVTLTTAAGHEMMRAAAQLAIE
AREIEKANDSVFRQPHAKKGHLMTKTALYEKPQ
>D3RXG7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Ferroglobus placidus (strain DSM 10642 / AEDII12DO)|TrEMBL
MVKVGILKMGAIGTALLVEYLLDERADREDIEVRVVTSGAKMQPEEAKIAEKLKEFDPDL
VLVVSPNAALPGPKAAREAFEGKPVIVISDAPAKKAKEEFEQKGFGYILVNADSMIGARR
EFLDPTEMALFNADVVKVLAATGAFRIVQEEIDKVIEALKKGEKPELPKVVITAERAVEA
AKFSNPYAKAKAMAAYFIAEKVADVDVRGCFIEKDPEKYIPLVAAAHEMMRIAAKLADEA
REIEKSNDTVFRNPHARDGKILSKTKLMEKPQ
>A0A133VI91|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|candidate division MSBL1 archaeon SCGC-AAA382A20|TrEMBL
MSDIRVGLAKLGNIGTSSMLDLMLDERAEREDVDFRVVSSGPKMGDEDGEDIVDKLLDFN
PDLIIISSPNPATPGPTAAREAVKDIDIPRIVIGDAPGTKIQEDLENIGYGYIFVLADAM
IGARREFLDPIEMAIFNADLIKVLSVTGAFRVVQEEIDNTISSLKSGSSSYVPEKIVDRN
TAVAAADFENPYARAKAMAAYEMASKVADLDVEGCFRVHEEKEYVPIVASAHEMMNTAAS
LAEEARKLEKGEDSVLRTPHADNGDMLKKRKLMKSPE
>A0A7J3TKG9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Geoglobus ahangari|TrEMBL
MVKVGVLKMGAIGTALLVEYLLDERADREDIEVRVITSGAKMQPEEAKIAEKLKEFDPDV
VIVVSPNAALPGPKAAREAFEGKPVIVISDAPAKKAKEELEQKGFGYILINADSMIGARR
EFLDPTEMALFNADVVKVLAATGAFRIVQEEIDKVIEAIKKGEKPELPKIVVTAEKAVAA
GNFQNPYAKAKAMAAYYIAEKVADIXVKGCFIEKDPDKYIPLVASAHEMMRVAAILADEA
REIEKSNDTVYRNPHARXGTILKKFKLMEKPQ
>A0A524LY61|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRSFGTGAKMGPAEAADTESFKQWNADF
VVIISPNAAAPGPTAARELWKDVPCIVVSDGPTKKEAREAFEQDGFGYIILPVDPLIGAK
REFLDSVEMASFNSDAMKVLSICGVVRLIQEELDRVTEQVASGRSGKELELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
ATQAREIEKSNDTVFRQPHAKSGALLKKVKLYEKPQ
>A0A0K8P219|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Ideonella sakaiensis (strain NBRC 110686 / TISTR 2288 / 201-F6)|TrEMBL
MKKLLYQFDTDPHPAVFDNVVAYDGGADHVTAYGGVTPANVGPLVDGAIFTRAPKDKKST
AIFVGGSDMAAGEALFAAVRAKFFAGFRVGTMLDSNGSNTTAAAAVAWLVHAAPGGSLKG
RHAVVLAGTGPVGQRAAAMLAREGARVAITGRDAARTQAAAQAIGARVGVEIEARVAPDL
AARTQAIEGASVVLATGAGGVPLLDEAAWQSQRHLLLLCDANATPPAGIAGIDLMDKGAQ
RHGKTVFGAIGFGALKIALHRACIARLFERNDLALDDEEIHAVARTMVG
>A0A2G1NW63|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon ex4572_44|TrEMBL
MVKVGFIKMGNIGTSIVIDLLFDEIAQREDSETRTFSSGAKMSKKEASQTEELKGWNPDL
VIMISPNAMAPGPVAAREIWKDVPTIVVADGPTKKEGRQKLEDAGFGYIVLTVDPLIGAK
REYLDTVEMVNFNADVTKTLAVTGAIRLVQETIDGVIEELKAGKTPTMPHILAKPEKCVE
YGGFANPYAKAKALAALHMLNKVAEINTPACFMMKDLVDIASTAAAGHEVARIAAILADE
AREIEKSNDRVSRKPHAKDGKILSKTQRMERSYPKPDCTRSHNKIKNKPIQSTPSYLILF
FIYPNTAQLCYS
>A0A139CRQ5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanolobus sp. T82-4|TrEMBL
MAKIGFIKLGNLGMSQVIDLVQDEIAAREGITVRVFGTGPKMGKDEAAATEELKKFDADF
YVMISPNSSAPGPTAARELYKDVPCIVISDGPTKKDDRAALEEAGFGYIIMTVDPLIGAK
TEFLDPVEMASFNSDAMKVLSTCGVVRLIQEELDKVAAMADEGKELELPHILAKPEKCIE
RAGFNNPYAKAKGLAALHMADMVAKINFPACFMMKEIEQVALTTAAGHEMMRAAAQMAIE
AREIEKANDSVFRQPHSKKGKLLTKTTLYEKPQ
>A0A8F5VJE7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanospirillum hungatei|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVTNMKAWGP
DFCIVVSPNGVLPGPKGAREALGAAGIPCVVITDDITTKKEEWEALKASEFGYIIMKGDS
MIGARREFLDPIEMADYNGNLIKVLSITGAFRKLQVALDEVIDQVKAGKKGKDLALPKIV
MSSDKAVEGEFSNPYAYAKARAAYEIAQAVAGVNVKGCFMTKGFENYTPIVASAHEMMRQ
ATLLCDEAREMEKATDAVIRKPHKNDGTRVAKKTLISKPE
>A0A2I0PSX1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon HGW-Methanomicrobiales-1|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLEPADVDRVVSNLKAYKP
DFCIVVSPNGVLPGPTGAREQLAAAGIPVIIITDDVTTKKEWEGVKASTFGYIIMKADSM
IGARREFLDPTEMADFNGNLVKVLALTGAFRKMQLAIDLVIDQVKAGKKGAELVLPKIVM
TTDKAVDGEFTNNYALAKARAAHEIAMAVAGQNVKGCFMTKEWEKYIPIVASAHEMMRCA
AALCDEAREIEKAGDSIMRKPHKKDGTLVCKNKLVAKFE
>A0A497JEL1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Hydrothermarchaeota archaeon|TrEMBL
MIRVGVLKTGNIATSLLVELLLDERADREDIDVKVISSGAKMTKEQVELTSKLLEFNPDL
VIYITPNCSLPLPKKIISKLVEKKPTIVISDAPGIKIKDELEKLGAGYIFVKADAMIGAR
REFLDPIEMAIFNADMLKVLAITGALRAVHEAIDNAIESIKAKKVNLPKLVLDKLAVARY
SGFANPYALAKAISAHIISEEVGKLNVEACFMTKTKEEYITKVASAHEMLRIASKLADEA
REIEKANDSVLRKPHSKQGLILEKRRLFDKFNKPRS
>A0A7J4PKN5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinaceae archaeon|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVCGTGAKMGPDDAAYTESFKQWDADF
VVIISPNAAAPGPTAARELWKDKPCIVVSDGPTKKDARQALEDEGFGYIILPVDPLIGAK
REFLDPVEMASFNADAMKVLSLCGVVRLIQEELDKVTDQVNTGKSGKELELPRIFAKPEK
CVEHGGFTNPYAKAKALAALHMAEKVAQVNFPACFMLKDIEQVCLATATGHEIMGAAAVL
ATQAREIEKSNDTVFRQPHAKDGTLLTKTKLYEKPQ
>A0A1F5DH36|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon RBG_13_38_9|TrEMBL
MKIGFAKVGNIACSPLLEFIFDERAERKDIEVRSFGSGSKMDPNSCVSIAEEVVKYKPDL
IVLSTPNAALPGPKKAMEIFKETKIPTVTVSDNPAKKAIKTMEEAGIGYIIVEGDVMIGA
RKEFLDPTEMACFNSDIIKILAVSGAFDVVRIEISKLIETIKKKESPELPKVVVTRSKAV
NSASFTNPYAKAKAASAYEMAQRAGELNFQGCFIEKEWEKYVQLVTSGHEIIRAAARLAD
EAREIEKYSDTLTRKPNDSDGEILRKTKLMEKPSGA
>A0A7C4H024|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MNTVVKVGVLKAGCLGSLPLLEFLLDERADREDISVRVVGSGAKVTVDECVECAREILKY
DPDFIIFAGPAQTTSGPTEARKILRESGKPVIIISDTPAKRIIKELEESGFGYIIIEADS
MIGARREFLDPTEMALYNSDVIRVLAITGVLSIIVEEIDKVISAIKSGVNPVLPRLIIDS
KLISGRSGFSNPYARAKAIAVYEIAKQVSAITVEACFKIHEPDLYIPLVAAAHEIMRNAA
RLADEAREMEKENDFVLRKPHFKDGSLGEKRSLMEKPIKIS
>A0A523WV34|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVKVTFVQAGYIGATTLIDALLDERASRKDISVRVISSGCKMDEAEAAAAAEIAAKVPTD
LYVCVSPNAGLPGPKKMREILKETGKPIIVVSDEPSRKAAKKLPEEGIGYIVLYADAMIG
AKRPFLDPIEMALFNADVIKVLSVTGVFRIIYTELDRVIEQIEKGEKLELPEVVVNKTRA
IAASGLQNPYARAKAMAAFEAARKVANLDVEGCFKTEGAQNYIPIIAAAHELLRYAAKLC
DEAREMEKANDSVERLVHFRDGTLRKKTQLLGKFE
>A0A419L2C7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MSGVVKLGVLKIGCIGTLPLLDIMLDERADRSDIDIRVMGSGAKLKEEQCREITALMIEQ
KPDLAILVGPAQTAPGPSEARKMLKEADIPTIIISDLPAKRLIDDVEKIGFGYIIVEADS
MIGARREFLDPVEMSLYNSDIIKVLAVTGTFNLVVEAIDEAIESIKRGESPKLPKLIIDG
EKAVEAAGFSNPYAKAKALAAYEMARGVSRITTRACFKIQDPNLYIPMVAAAHEIMRLAA
KLADEAREIEKSQDAVLRKPHFKDGRIGTKRSLMEKPIKPSF
>A0A842SLD5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVTVTFVKLGFIGTTILIEALLDERSSREDLKTRVISSGVRMDDEEAEFVANMAKTVESD
LYVVISPNAALSGPKKARKILRETGKPIIVISDEPSRKSLKGLDDEEDMGYIVIYGDPMI
SAKTAFLDPVEMAIFNSDVLRVLAVTGAFRLIHTSIDNVIEQIKNGEKPELPKIIMNKKR
ALEAADIMNPYAYGKAMAAYEISRNVASLSTEAVFKISDRDEAVPVLTAAHEMIRQAALL
ADEAREIEKSNNTAVRVVHFKSGALKRKTGLYDKFE
>A0A497MZE1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
HSEIDRVIEEIEQGKEPVLPMIVVNKKRALEYSGIKNPYARAKAMAAFEAARKVANLDVE
GCFKTKGAANYLPIVAAAHELMRGAAKLCDEAREIEKAHDSVERLVHFKDGKLKRKTKLL
GKFE
>A0A419KVH5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MIRVGFLKLGNIATAPMIELLLDERAEREDIEVRVVTTGANMSPEQAEEAAKTLLSLKPR
IVLITSPNASTPGPKRAREIISGEGVPTVVVSDGPKKIVESLAKKGIGCIIVEADSMIGA
RREFLDPVEMALFNSDVIKVLAVTGAYTLLFKTIDGLITDLKEGREPKLPSLVINSALAT
EAAGFKNPYAKAKAYAAYEIARRVSSLTTEACFKVKEWEVYTSLCAAAHEMMRIAASLAD
EAREIEKYGDSVLRMPHYDDGTILVKRALIEKPKGK
>A0A419KK31|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MPQPVKVGIIKVGCIGTLPLIEILLDERADRKDIDVRVVGSGAKLGVEQCREVTELMIKQ
APEMAILIGPAQAAPGPTESRRLLREAGIPTIVISDGPAKKITKDLEKDGFGYIIVEADS
MIGARREFLDPTEMAIYNADVIRVLAATGSLMLIVEEIDKVIDAIKNGKKPDLPRVLITK
ELVASRFKNPYAAAKASAAYEIARHVAEINVEACFKVREWTMYTHLAATGHEMMRIAAKL
ADEAREIEKGIDSVLRKPHFKDGRLGEKSSLIEKPKKPDASSQ
>A0A7K4B723|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVTNMKAWGP
DFCVVVSPNGVLPGPKGAREALGAAGIPCVVITDDITTKKEEWEALKASDFGYIIMKADS
MIGARREFLDPIEMADYNGNLVKVLSITGAFRKLQIALDEVIDQVKAGKKGKDLALPKIV
MSSDKAIEGEFSNPYAYAKARAAYEIAQAVAGVNVKGCFMTKGFENYTPIVASAHEMMRQ
AMLLCDGAREMEKATDAVIRKPHKNDGTRVAKKALISKPE
>A0A7K4BNV6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon|TrEMBL
MVVKVGIAKLGNIASGVMGELLLDERADREDMITFMATSGTKLQPEDIDRVVSNMKAWGP
DFCIVVSPNGVLPGPTQAREDLAAAGIPCIVITDDVTTKKEQFEALKASNFGYIIMKADA
MIGARREFLDPIEMADYNGNLVKVLAITGAFRKMQVELDKVIDQVKAGKKGADLVLPKVV
MTSDKAVDGEFTNPYALAKARAAYEIAQSVAGVNVKGCFMTKEWEKYIPIVSSAHEMMRQ
AMILCEEARDLEKAMDGVIRKPHKKTGEIVSKTALISKPE
>A0A662W1B1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobales archaeon|TrEMBL
LLEYLLDERADREDIEVRVVTSGAKMQPDEAKVAEKLKEFNPDLIIVISPNAALPGPKAA
REAFEGKPVIVISDAPAKKAKDEFKERGFGYILINADSMIGARREFLDPTEMALFNADVV
KVLAATGAFRLVQEAVDNVIDQLKAGQKPDLPQIIVTAERAVEAGKFSNPYAKAKAMAAF
YIAEKVADIDVKGCFIEKDPQKYIPLVTSAHEMMRIAAMLADEAREIEKGNDTVYRTPHG
RDGKVLSKVELMVKPE
>A0A833DT99|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermococcus okinawensis|TrEMBL
MVVKVGIIKCGNIGTSPLVDLILDERADRKDIDVRVLGSGAKMGVEQVEEVTKKMIEDIK
PDLIVFISPNPAAPGPKKARELLSKCGIPSVIIGDTPGLKVKDDIEKEGLGYIIVKCDPM
IGARREFLDPIEMVLFNADVLKVLAGTGAIRVVQNAIDSMINAIKEGKEVELPKIVVNES
KAVESMEYTNPYAKAKAMAAFKIAEMVGDTNVKGCFMVKEREKYLPVVASAHEMIRYAAK
LVDEAREIEKSLDTVSRKPHGTDGRILNKKKLMEKPE
>A0A7J4PSG7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanotrichaceae archaeon|TrEMBL
MFKIGFIKLGNVASSLVADLALDEIAERTDIEARSLCFGAKMTKKEAEMSRELKNWGPQL
VVMVGPNAATPGPTAARELYKDVPTIVISDGPSKKDAREALETDGFGYIILPFDPLIGAK
REFLDPAEMALFNSDALKVLSVCGSVRLVQEELDKAMASILAGDPQLPHILGNPEKCTER
MNFKNPYARAKAIGALHMAQTVAGIDAQACFRLKELERIALTAAAGHEVMRAASKLADEA
RELEKSSDSVSRKPHARSGAILEKTGLLDKPEPI
>A0A0E3QR80|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina barkeri str. Wiesmoor|TrEMBL
MVNIGFIKMGNLGMSQVINLVQDEIAAREGITVRVFGTGAKMSPAEAAASESFKQWNADF
VIIISPNAAAPGPKAAREIWKDVPCIVVSDGPTKKEAREALENNGFGYLILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLVQEELDKVTDQVASGKSGKELELPHIFAKPEK
CVEYAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAASQL
AIQAREIEKSNDTVLRQPHAKNGTLLKKVKLYQKPE
>A0A2P0QL27|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLEPADVDRVVSNLKAYKP
DFCIVVSPNGVLPGPTGAREQLAAAGIPVVIITDDVTTKKEWEGVKASKFGYIIMKADSM
IGARREFLDPVEM
>D5VSM6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocaldococcus infernus (strain DSM 11812 / JCM 15783 / ME)|TrEMBL
MVKVGIVKCGNIGTSLVVDLALDERAERDINVLVYGSGAKMNPESVEYVVKKMIEEKPDL
IIYIGPNPAAPGPRKARELLSECKIPSIIIGDAPGIKVKDEMEKEGLGYILIKGDPMIGA
RREFLDPTEVALFNSDILKVLAVTGVVRLVQEEIDRVIEYIKEGKEPELPRIVVDAEKAV
ERMEYSNPYAKAKAIASYNMAEEVANIDVKACFMVKEPERYIILAASAHELLRQAAKLAD
EARELEKATDMVSRKPHAKDGRILSKRKLLEKPQ
>A0A0E3R8V4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina mazei SarPi|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMAPADAADTESFKQWNADF
VVIISPNAAAPGPTAAREIWKDVPCIIVSDGPTKKEAREAFEQEGFGYIILPVDPLIGAK
REFLDSVEMASFNADAMKVLSICGVVRLIQEELDKVTEQVASGKSGKDLELPHIFAKPEK
CVEHAGFANPYAKSKALAALHMAEKVAQVNFPACFMLKEIEQVCLTAAAGHEIMGAAAQL
ANQAREIEKSNDTVSRMPHTKNGAVLKKVRLYEKPE
>A0A832D3Z2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus sp|TrEMBL
MSKVKVGVLKMGAIGTAVILEYLLDERADREDIEVRVVTSGAKMQPEEAVVAEKLKEFNP
DLIIVASPNAALPGPKAAREAFAGKPVIVISDAPAKKAKDELKEKGFGYIFLNADSMIGA
RREFLDPTEMALFNADVLKVLAATGALRVVQEAIDKVIEDIKAGKKPELPQIVVTAEKAV
EAAKFSNPYAKAKAMAAYFIAEKVADINVRGCFVEKDYNVYVPLVASAHEMMRIAAMLAD
EAREIEKYGDKVFRNPHSRDGKILSKIELISKPQ
>A0A523RW48|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thorarchaeota archaeon (strain OWC)|TrEMBL
MSESTINVGVIKLGAIASAPLLDLMFDERAERKDINVRAFTSGAKMDEESSVGPTESVIA
WAPHLVLIVSPNAALPGPTKVREMLAEAKLPTISISDGPAAKAFYKKNEEGKKKPHVLDG
QGFIVIPSDSMIGAKKEFLDPTEMSLFNADAIKVLSITGVARAIQIELDKVVTALQAGET
PEMPQVKLTAEKAVKCGYFGNPYAKAKAIAALTIAEAVADITTKGCFKTKEAEKYIPLVA
AGHEMMRVAANLADEVRELEKAGDSVVRNPHVSKGLVKTKTVLMDKPK
>A0A2H9I0Y6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon B24-2|TrEMBL
MGCLGSVPLLEFLFDERAERTDLDVRVVGSGAKLGPEQCVEVTKTLLNLKPDFIIVAGPA
QQTAGPKEARKLLADSGIPTLIISDGPMVRIKGELEKAGFGYIIVEADPMIGARREFLDP
VEMAIFNSDVIKLLACTGVFNVIVDAVDRIIESLKRGEKPSLPHIVVDRNLALKAAEYSN
PYARAKALAAFDLAKQVTSLHVEACFKLTDWKEYTLLVAAGHEGVRLASKLSEEAREIEK
ASDSVLRRPHHRDGVRSRKRALIEKPKKD
>A0A7C4HAD8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MNKIVKIGILKAGCIGSLPLIEFLLDERADREDIQVKVIGSGAKVTTEQCVNSAEQILKY
DVDLIIFIGPAQTTQGPSEARKILRASNKPVIIVSDSPAKRIIKELDESGFGYIIVEADS
MIGARREFLDPTEMALYNSDVIKVLAVTGALNVIFEEIDKVINAIKSGGKMILPKLILDS
KKAVEAARFSNPYAKAKAMAAYELAKQVSAITFEACFKVQEPDLYIPLVATAHEIMRAAA
RLADEAREIEKGGDSVFRRPHFKDGLLGEKRRLMEKPQKVADQNNIQLTEDKQI
>A0A1L9C7D4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanohalophilus portucalensis FDF-1|TrEMBL
MVKVGFIKLGNLGMSQVIDLVQDEIAAREGISTRVFGTGPKMDKETAASTEELKAWEPDF
VVMISPNASAPGPKSARELWNDYPCIVVSDGPTKKDDRQALEDAGFGYIIMTVDPLIGAK
TEFLDAVEMASFNSDAMKVLSTCGVVRLLQEELDAVTAQVDEGKSGADLELPHILAKPQK
CIERAGFNNPYAKAKGLASLHMASKVAEVNMPACFILKEIEDVALTAATGHELMRAAAQL
AIEAREIEKANDSVFRQPHSKKGVQLQKTKLYEKPQKV
>A0A0F8P4R8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina mazei|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMAPADAADTESFKQWNADF
VVIISPNAAAPGPTAAREIWKDVPCIIVSDGPTKKEAREAFEQEGFGYIILPVDPLIGAK
REFLDSVEMASFNADAMKVLSICGVVRLIQEELDKVTEQVASGKSGKDLELPHIFAKPEK
CVEHAGFANPYAKSKALAALHMAEKVAQVNFPACFMLKEIEQVCLTAAAGHEIMGAAAQL
ANQAREIEKSNDTVSRMPHAKNGAVLKKVRLYEKPE
>A0A6A8RHC6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium sp|TrEMBL
MVVKIGIIKCGNIGTSPVIDLLLDERADRPNIDTCVVGSGAKMNPEEIEKAVPLMLEMDR
DFVIFISPNPGAPGPAKARELLSAADVPAIIIGDAPGLRSKDEMDEQGLGYIIVKADPMI
GARREFLDPTEMASFNSDVIKVLALTGAYRVVQDTIDAAVTAVESGEAIELPKVVITRDK
AVEAAAFSSPYAKAKAMAAYEIATKVADIDVEGCFMVRDAEKYIPLVASAHEMLGVAAKL
ASEAREIEKANDTVVRTPHGGKGQTLSKVALADKPE
>A0A1V4YAQ1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomethylovorans sp. PtaU1.Bin093|TrEMBL
MAKIGIIKLGNLGMSQVVDLVQDEIAAREGITVRVFGTGPKMGKDEAAATADLKKMEADF
YVMISPNSSAPGPTAARELYKDVPCIIISDGPTKKEDREALQQAGFGYIIMTVDPLIGAK
TEFLDPVEMASFNSDAMKVLSTCGVVRLIQEELDKVAAQVDAGEPIQLPHILAKPEVCIE
RAHFNNPYAKAKGLAALHMADMVAKINFPACFMMKELEQVALTTAAGHEMMRAAAQLAIE
AREIEKANDSVFRQPHSKKGGKQFQKTKLYEKPQ
>A0A832Z2R3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus profundus|TrEMBL
MVKVGIFKMGAIGTAILLEYLLDERADREDIEVRVITTGSKMRESDAKVGEKLKDFNPDL
VIVVSPNASLPGPKVARELFKGKPVIVISDAPAKKIVDELEKEGFGYILVTADSMIGARR
EFLDPTEMALYNSYILNVLTITGALRLVQEEIDKV
>A0A843HCI5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosphaera sp|TrEMBL
IPLVVAAHEMMKAASILAEEAREIEKSNDTVTRTPHKRDGSIVFKSKLLHNFESEDTFDY
HEE
>A0A347AMA3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium sp. BAmetb5|TrEMBL
MVVKIGVIKSGNIGTSPVLDLVLDERADRPNIDVRGVSSGAKMNPEQVEEIVPKIADFDP
DFVIFISPNPGAPGPAKARELLSGMDVPALIIGDAPGMGKREEMDEQGLGYIVVLGDPMI
GARREFLDPTEMASFNADVIKVLAATGAYRVVQETIDGMIAACEAGEDIELPKVVIDAAK
ATETAGFASPYAKAKAMAAYEMAAKVGDIDLKGCFMVKDMEQYVPIVASAHELIATAAKL
ATEAREIEKANDTVLRKPHGAQGQTMSKTVLVSKPE
>A0A1V5A6E5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoregulaceae archaeon PtaU1.Bin059|TrEMBL
MVNVKGCFMTKEWEKYIPIVSSAHEMMRVAAVLCDEARELEKACDGVIRKPHKKDGVIVS
KTKLISKPE
>A0A177IWD1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methylorubrum populi|TrEMBL
MSKKLLFQFDTDPTPSVFDVVVGYDGGADHITGYGNVTPDNVGAYVDGTIYTRGGKEKQS
TAIFVGGGDMAAGERVFEAVKKRFFGPFRVSCMLDSNGSNTTAAAGVALVVKAAGGSVKG
KKAVVLAGTGPVGMRSAALLAGEGAEVVLCGRKLDKAQAAADSVNKRFKVNVTAAETPDD
ASRSEVIKGAHLVFTAGAIGLELLPQAAWQNESSVEIVADYNAQPPLGIGGIDATDKGKE
YGGKRAFGALGIGGLKLKLHRACIAKLFESSEGVFDAEEIYKLAKEMA
>A0A656YXJ9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|candidate division MSBL1 archaeon SCGC-AAA259J03|TrEMBL
MVEVRVGLAKLGNIGTSSMLDLMLDERAEREDIDFRVLCSGPKMRKEDGKELADKLQGFD
PDLIIISSPNPSTPGPTAARETVSDLDIPRVIIGDAPGTRIKDDLEKAGFGYLFILADAM
IGARREFLDPIEMSLFNADLIKVLSVTGAFRVVQEEIDKIISAEKTGNSYIPQLVVDRDT
AISAADFENPYARAKAMAAYEMASKVADLDVEGCFQVHEESKYVPIVASAHEMMRSAANL
ADEARELEKSEDSVLRKPHADDGDILSKNKLMESLK
>A0A7J2TJL3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus fulgidus|TrEMBL
MSKVKVGVLKMGAIGTAVILEYLLDERADREDIDVRVVTSGAKMQPEEAVIAEKLKEFNP
DLIIVASPNAALPGPKAAREAFAGKPVIVISDAPAKKAKDELKEKGYGYIFINADSMIGA
RREFLDPIEMSLFNADVLKVLSATGALRAVQEAIDKVIEDIKAGRKPELPQLIITAEKAV
EAGKFSNPYAKAKAMAAYYIAEKVADLTTRGCFVEKDYNVYVPLLAAAHEMMRIAAILAD
EAREIEKYGDKVFRNPHARDGRILSKVELISKPQ
>A0A849QJ61|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinaceae archaeon|TrEMBL
MAKIGFVKLGNLGMSQVIDLIQDEIAAREGIEIRSLGTGPKMGKDEAAETEYLKKMDADF
YVMISPNSSAPGPTAARELYKDVPCIVISDGPTKKDDRKALEDAGFGYIIMTVDPLIGAK
TEFLDPVEMASFNSDAMKVLSTCGVVRLIQEAFDDVAAQVDAGKSGKDLELPHILAKPEK
CIESAGFANPYAKAKALAALHMADKVAQINFPACFMMKDIEQVTLTTATGHEMMRAAAQL
AIDAREIEKSNDSVFRQAHSKKGNIVRKTKLYEKPQ
>A0A7K4INL4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MTEVQAKKIGVFKCGNIASSPIFELLLDELADRQDIKTRTVTTGSKMSAEDVEEALPKIF
DLNPDLLVLISPNPSIAGPAKVREKFSTSGIPSIVISDAPAKRVKAELEKQGLGYIIITG
DPLIGARREFLDPLEMAIFNSNIIKVLAITGVYRIVHREIDKLVYALKTGLSPVLPKLII
DVNSIRDNSDFKNPYAKAKAMAAYELTEKIAEINLQACFIEKESDKYIPLVACAHEIAQA
AAILAEEAREIEKYNDTLVRKPHAKDGRAKVKTKLMLPLTFDEEFYGKE
>A0A7J2T7M8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKNVRVGIFKCGNIGTAPILELLLDELADREDITVRCITTGAKMLVEEVEEALPKIFDFK
PDFIVFISPNPAVRGPTRAREILLERKMPAVFISDAPGKRVIEEFEKAGFGYIIIMGDPL
IGARKEFLDPLEMAIFNANVIKVLAITGVFRIIHQEIDKIIYSIKEELIPQLPRLVIDTD
TIRDRSD
>A0A1V5B8J4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosaeta sp. PtaU1.Bin112|TrEMBL
MFKIGFVKLGNIATSTAVDLSLDEIAERTDIEFKIVSFGPKMTKKEGEAAAELLAWQPQL
VVISSPNAATAGPTIARELLKGVPTIVISDGPSKKESRDALAAEGFGYIILPMDPLIGAK
REFLDPTEMALFNSDALKVLAACGAIRLVSEELDLAMASIAAGEAKLPTILATPEKCAER
MRFGNPYARAKAVGALYMAQTVASIDAAACFRLKELEAIALAAAAGHEVMRAAGRLADES
REMEKANDSVSRRPHARTGEIMSKTGLLEKPEKI
>A0A6B9TIV5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermobacter sp. THM-1|TrEMBL
MVVKIGIIRCGNIGTSPVLDLLLDERADRPNIDVCVVGSGAKMNPDEIERAVPTMLEMDR
DFVIFISPNPGAPGPAKARELLSEADVPAMIIGDAPGLRVKDEIEEQGLGYIIVKADPMI
GARREFLDPTEMASFNSDVIKVLAFTGAYRVVQNTIDAMIADVEAGKAPELPQIVIDTDV
AVDAAGYENPYAKAKAMAAYEIATKVADIDVKGCFMVQDPEKYIPIVASAHEMLSAAARL
AAEAREIEKANDSVLRTPHGKEGETLSKTDLLAKPE
>A0A7K4CFY8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLEPADVDRVVSNLIAYKP
DFCVVVSPNGVLPGPTGAREKLAAAGIPTIIITDDVTTKKEWEGVKADTKFGYIIMKADS
MIGARREFLDPVEMSDYNGNLVKVLALTGAFRKLQVALDKVIDQVKAGKKGAELELPKII
MTTDKAVDGEFTNPFALAKARAAHEIAIAVAGQNVKGCFMTKEWEKYIPIVTSAHEMMRV
AAVLCDEARELEKAGDCILRQAHKKDGTLVRKTKLVAKFE
>A0A2V3JBQ3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanophagales archaeon|TrEMBL
MLKVGFVKLGNIGTSRIVDLLLDERADREDIDVRVLGTGAKMTPEVAADTARLLDWDPDM
VVVISPNAALPGPKRAREMVKERGKPCIVISDGPAKKAVNELKENGFGYLIIPGDPMIGA
RREFLDPVEMSIFNSDVLSVLSVTGAMRLVQEEIDSVIEALKAGKEAKLPQMIVTAEEAV
ERAKFSNPYAKAKAIAAYNMLERVAEMDARGCFMMKDPADYIPMVAAAHELLREASKLAF
EAREMEKQADRLVREPHARSGELRSKEKLLEKPGA
>A0A0A0BHS7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methylophaga thiooxydans|TrEMBL
MSKRSIIHMINPMKHNSPFDINMALDAGYDILMPYQHVKLEEVSGLTQDAIFSRGPSGVK
KTGMFIGGRDIGLAMDMLDAAKKAMVPPFEISVFADPSGAFTTAAALVACVERELKKNFN
KGYEGTKAVVFGGTGPVGLATAVIAALQGADTTIVDHFSIDTALEFAEEAKRRYGVQLRA
TTAASDADKARLLSDAEAVFCTAKAGIQVLNASVLSDAKQLKVAGDVNAVPPLGIEGVEL
MDSGTPLLLAKNSPNAVGIGALAVGNVKYKLQQALLRETLEAEKPVYLDFRNAFEGARKL
A
>A0A833DPF7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermococcus okinawensis|TrEMBL
LDERADRKDIDVRVLGSGAKMGVEQVEEVTKKMIEDIKPDLIVFISPNPAAPGPKKAREL
LSKCGIPSVIIGDTPGLKVKDDIEKEGLGYIIVKCDPMIGARREFLDPIEMVLFNADVLK
VLAGTGAIRVVQNAIDSMINAIKEGKEVELPKIVVNESKAVESMEYTNPYAKAKAMAAFK
IAEMVGDTNVKGCFMVKEREKYLPVVASAHEMIRYAAKLVDEAREIEKSLDTVSRKPHGA
DGRILNKKKLMEKPE
>A0A2P0QM90|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon|TrEMBL
AKLGNIASGVMAELLLDERADREDMQTFMATSGTKLEPADVDRVVSNLKAYKPDFCIVVS
PNGVLPGPTGAREQLAAAGIPVVIITDDVTTKKEWEGVKASKFGYIIMKADSMIGARREF
LDPVEM
>A0A2P0QL51|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon|TrEMBL
SKFGYIIMKADSMIGARREFLDPIEMADYNGNLVKVLAMTGAFRKLQVALDKVIDQVKAG
KKGDAIELPKLIMTTDKAVDGEFTNPFALAKARAAHEIAMAVAGQNVKGCFMTKEWEKYI
PIVAS
>A0A5C9F0K5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MSEKVLKIGVLKNGTIGSSVLLSFLIDERAEAERVIFREVSSGPKMHPPEECVETMNKLL
EFEPELILMSSPNAALKGPVKARELVGDIPAIVISDAPTKKAVDEIKEKGLGYIIVECDS
MIGARRPFLDPIEMSFFNANLLKVLAGTGVFQIIVEELNKVIMEMLEGKTPTLPQIIIDA
EMAVSRAGFSNPYAEAKAIAAFEIAAQVSKITGKACFAMKERERYMPQLAAAHEMMKNAS
ELTQIAREIEKSNDTVMRTPHHKDQYLLKKTKLHEKEK
>A0A524D0Y8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MNGKLNIGVLKNGTIGSSVLLSFLIDERAEGERVIFREVTSGPKMHPPEECVETMKKLLE
FNPDLILMSSPNAALKGPKAARELVGNIPAIVISDAPAKKAIEEFKEKGIGYIIVECDSM
IGARRPFLDPIEMSVFNSNLLKVLAITGVFNIIVDELNAVIMDMLEGKTPTLPQIEIDAA
KAAQAARFSNPYAEAKAIAAFEIAAKVSKITGKACFVLKEREEYMPQLAAAHEMMKTAAD
LCQIAREIEKSNDTVLRRPHRSSQELLQKRALHEKEK
>A0A7C4TRJ2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus sp|TrEMBL
AASMIGARGEFLDPTEMALFNADVLKVLAATGALRVVQEAIDKVIEDIKAGKKPELPQIV
VTAEKAVEAGRFSNPYAKAKAMAAYFIAEKVADINVRGCFVEKDYNVYVPLVASAHEMMR
IAAILADEAREIEKYGDKLFRNPHSREGKILSKTELISKPQ
>A0A524LIV1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thorarchaeota archaeon (strain OWC)|TrEMBL
AKAYAALTMLESIADITSTACFKESDPEVYIPAVAAAHELLRAAARLADEAREIEKQNDT
VLRTSHGSSGKATKKTKLLEKPK
>A0A1M4MNG8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoculleus chikugoensis|TrEMBL
MGELLLDERADREDMITFMATSGTKLQPEDIDRVVSNMKAWGPDFCIVVSPNGVLPGPTQ
AREDLAAAGIPCIVITDDVTTKKEQFEALKASNFGYIIMKADAMIGARREFLDPIEMADY
NGNLVKVLAITGAFRKMQVELDKVIDQVKAGKKGADLVLPKVVMTSDKAVDGEFTNPYAL
AKARAAYEIAQSVAGVNVKGCFMTKEWEKYIPIVSSAHEMMRQAMILCEEARDLEKAMDG
VIRKPHKKTGEIVSKTALISKPE
>D7DR53|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcus voltae (strain ATCC BAA-1334 / A3)|TrEMBL
MVVKVGIIKCGNIGMSPLVDLSLDERADRNDIDVRVVGSGAKMGPEQVEEVTKKMIEDIK
PDFVLYIGPNPAAPGPKVARELLSAADIPAVIIGDAPGIKDKDAMAEQGLGYILIKCDPM
IGARRQFLDPVEMSMFNADVVRVLAGTGAVRVVQNAIDAMIYAVEEGKEIELPKIIVTDA
KAVAAAEFSNPYAKAKAMAAFVMAEKVADIDVKGCFMTKEMDKYIPIVASAHEMIRYAAK
LVDEARELEKATDGVSRKPHAGPGAILNKSKLMEKPE
>A0A2A5P0S0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Geothermarchaeota archaeon ex4572_27|TrEMBL
MAEKKPVRICVVKLGALGTSVLLEYLLDERADRGDIEVRVFTTGSKMFPEQYGAELAEKV
AGEDFDLYIVVSPNATTPGPTKARELLKERGKRVIVISDAPTARIAKELEEKGFGYIIVQ
ADAMIGARREFLDPVEMALFNSDVIRVLAITGAYRALQVELDKVIDALKKGSEPELPKLI
LDKETTVAKYGEFKNPYARAKAMAAYEIARRVADLTVEGCFKVKEWERYVPIVAAAHEMM
RIAAALADEAREIEKSNDTVVRTPHAVDGTILRKEKLIEKPARPSGAAS
>A0A843DH95|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocorpusculum sp|TrEMBL
MVVKVGVAKLGNIAAGVMAELLLDERADREDMMTFMATSGTKLQKEDVDRVVSNLKAWQP
DFAIVVSPNGVLEGPVGAREELAAAGIPVIVITDDVTTKKEGWEALKASNFGYIIMKADA
MIGARREFLDPVEMADYNGNLIKVLATTGAFRKLQQELDKVIDQVKEGKKGAELVLPKLV
VNSDNATKGEFTNPYAHAKARAAYEMAQSVANINVKGCFMTKAWEDYIPIVASAHEVMRQ
AAALCDEAREIEKGCDGVIRMPHKKTGEIVSKTALISKPE
>A0A2A2HWT9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina spelaei|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMSPAEAAASESFKQWNADF
VVIISPNAAAPGPTAAREIWKDVPCIVISDGPTKKEAREAFEKDGFGYIILPVDPLIGAK
REFLDPVEMASFNSDALKVLSVCGVVRLIQEELDKITGQVASGKSGKELELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
AIQAREIEKSNDTVFRQPHAKNGNLLKKVTLYQKPE
>A0A8J8C619|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermococcus sp. SCGC AD-155-M21|TrEMBL
MVVKIGIINCGNIGTSPLIDLILDERADRKDIDVRVLGSGAKMGVEQVEEVTKKMIEDIK
PDLIIYIGPNPAAPGPKKARELLGNCDIPGVIIGDAPGLRVKDEIAKEGLGYIIIKCDPM
IGARREFLDPTEMALFNSDVLKVLAGTGALRVVQNAIDSIIDALKEGKEVQLPNIVINET
KALEAMEYNNPYAKAKAMAAFKIAEMVGDINVKGCFMVKEMEKYIPVVASAHEMIRYAAK
LVDEAREMEKSQDAVSRKPHASDGRILCKNKLIEKPQ
>A0A800UEY0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon Met12|TrEMBL
MAKVKIGFVKLGALGITQVVDLLLDERAERDIDIRTVGTGAKMGKDEAGYAEKLMEWDPD
LVVVVSPNASLPGPKIAREAVKDTPCIVISDGPTEKIKDGLAKEGFGYIILKGDPLIGAR
REFLDPVEMTLFNTDALRVLTICGAVRLVQEELDAAIEGVRQGNVKLPHITAGAETVVDR
AGFANPYARAKAMASYKMAELVAEMNVQTCFVLREPPKYIMMGAAAHEVMRTAALLANEA
REIEKGADSVSRKPHDDDGNILSKRRLLDIPE
>A0A7C1E1S1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoculleus sp|TrEMBL
DLELPKIVVTADKAVKDEFTNPYAYAKARAAFEIAAAVAMVNVKGCFMTKGFENYVPIVA
SAHEMMRAATVLCDEAREIEKGVDGVVRKPHKNDGTIVSKTTLISKPE
>A0A125NVE2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Hyphomicrobium sulfonivorans|TrEMBL
MSDATPILHMLSPQKHMSPFDVNMAADAGYKVIVPYINVTLEEVTALTQDAIFSRPPNYG
TRTGLFIGGKDAILALDMLDAAQKALVPPFGLSTFADPAGSFTTAAAMVACVERVLRTKF
NRGWKGTKVAVFGATGVVGFASSIIAALEGAEVTLVAHRGVDRVIKSAEVSKERFGVDLI
AKSGETLEQKQAIIADAEVVFAAAAAGVRVLSAEDLALAKNLLAVADVNAVPPAGVEGME
LFMDGGELPGSKALGVGPLAIGDIKYKTESGLFKQMINSTEPVHFDFRAAFALARTLTA
>A0A0E3PHK8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina siciliae HI350|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVCGTGAKMGPADAADTESFKQWNADF
VVMISPNAAAPGPTAAREIWKDVPCIVVSDGPTKKEAREALEQEGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSNCGVVRLIQEELDKVTEQVASGKSGKDLELPHIFAKPEK
CVESAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEVEQVCLTAAAGHEIMGAAAIL
ATQAREIEKSNDTVLRQPHAKNGTLLKKVKLYEKPE
>A0A497MLY6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MRVGVVKCGNIGTAPLFELLLDELADREDIAVRSITTGSKMMAEAVEEALTSMFEFSPNL
IIFISPNPAVQGPKRAREILSEKNIPCIFISDAPGKRLREEFEKLGFGYIVVMGDPLIGA
RKEFLDPTEMALFNSNIIKVLAITGVYNIILREIDRIIHNLKENLIVELPKLVIDTGEVR
DKSDFKNPYAKAKAMAAYELTKKIAEINTKACFIEKEKEKYIPLVACAHEIAQAAARLAE
EAREIEKYSDVLTRRPHARNGKPKIKERLMEKPTFDEETYQEWFK
>A0A7C2ZW08|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MRVGVVKCGNIGTAPLFELLLDELADREDIAVRSITTGSKMMAEAVEEALTSMFEFSPNL
IIFISPNPAVQGPKRAREILSEKNIPCIFISDAPGKRLREEFEKLGFGYIVVMGDPLIGA
RKEFLDPTEMALFNSNIIKVLAITGVYNIILREIDRIIHNLKENLIVELPKLVIDTGEVR
DKSDFKNPYAKAKAMAAYELTKKIAEINTKACSIEKEKEKYIPLVACAHEIAQAAARLAE
EAREIEKYSDVLTRRPHARNGKPKIKERLMEKPTFDEETYQEWFK
>A0A7J2YES9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
ILAAAHEIMRYAAELADEAREIEKYGDTLVRTPHSSDGTILFKEKLMEEARGR
>A0A497PLK7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVKVGILKLGCIGTAPLLEFLLDERAERSDIQVRVVGSGASMNPKQCKEAAEALIQYKPD
FSVVISPNAAVSGPKLGRNLLSKAGIPTLVVSDLPAKKITKELEAEGFGYIIVEADAMIG
ARREFLDPIEMALFNSDMIRVLAITGVFKVLINELDKVIELIKAGNKVILPKIIINVEKA
STHSSLVNNYAKGKAMAAHEIAKNVGRVTRKGCFIIKEWEKYTVTVASAHEMMRTAAKLA
DEAREIEKTGDHVMRYPHHPDGSKTRKLKLIEKPSKNGE
>A0A842M3P0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobi archaeon|TrEMBL
MTRIGFVKLGNIGISTVIDLILDERADREDIDVRTISSGSKMTPEVVEDLKKINELSPEL
LVIVSPNASLPGPKKMREAVESPCIIVSDAPAKKAVKKLEEGGFGYIIISGDPMIGARRE
FLDPTEMALFNAEVLKILSVSGVVKIIQEELDKALESLKGGELYLPRRIIEIDDIISLDF
SNPYAKAKAVAAYFIAEKVAELNVRACFTEKDREKYVPMVAAAHEMIRIASQLSDEAREL
EKAVDGVIRTPHGKDGRILFKRALMEGFQK
>A0A498HC42|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanohalophilus sp. WG1-DM|TrEMBL
MGNLGMSQVIDLVQDEIAAREGISTRVFGTGPKMDKETAASTDELKAWEPDFVVMISPNA
SAPGPKSARELWNDYPCIVVSDGPTKKDDRQALEDAGFGYIIMTVDPLIGAKTEFLDAVE
MASFNSDAMKVLSTCGVVRLLQEELDAVTAQVDEGKSGADLELPHILAKPQKCIERAGFN
NPYAKAKGLAALHMASKVAEVNMPACFILKEIEDVALTAAAGHELMRAAAQLAIEAREIE
KANDSVFRQPHSKKGAQLQKIKLYEKPQKV
>A0A2P0QM25|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon|TrEMBL
IIMKADSMIGARREFLDPVEMSDYNGNLVKVLALTGAFRKMQLALDKVIDQVKAGKKGDA
IELPKLIMTTDKAVDGEFTNPFALAKARAAHEIAMAVAGQNVKGCFMTKEWEKYIPIVAS
AHEMMRAAAVLCDEARELEKAGDSILRQAHKKDGTLVAKKKLVAKFE
>A0A8J7S510|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcus voltae|TrEMBL
MVVKVGIIKCGNIGMSPLIDLSLDERADRNDIDVRVIGSGAKMGPEQVEEVTKKMIEDIK
PDFVLYIGPNPAAPGPKVARELLSAADIPAVIIGDAPGIKDKDAMAEQGLGYILIKCDPM
IGARRQFLDPVEMSMFNADVVRVLAGTGAARVVQNAVDAMIYAVEEGKEIELPKIIVTDA
KAVAAAEFSNPYAKAKAMAAFVMAEKVADIDVKGCFMTKEMDKYIPIVASAHETIRCAAK
LVDEARELEKATDAVSRKPHAGAGAILNKSKLMEKPE
>A0A524FCZ7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MSEEKVLKIGILKNGTIGSSLLLAFLMDERAEATRINVYEVTSGAKMHPPEMCTETMKDL
LKWEPELIIMSSPNAALKGPKAARDMAGNIPTIIISDAPAKKAVEEITEKGMGYILVNCD
SMIGARRPFLDAIEMSIFNADLLKVLAITGALSIIAQELNKVIMDMLEGRTPTLPQIIVD
ADNATEAAGFSNPYARAKAIAAFELASSVSKVTSKACFVLKEREEYMPLLAAAHEMMSNA
AKMCDEARNIEKSNDTVLRRPHHANQNLLTKTALMDKES
>A0A1V5A4I6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoregulaceae archaeon PtaU1.Bin066|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVNNMVAWKP
DFAIVVSPNGVLPGPTGARERLLASGIPTVFITDDVTTKKEWAEIKDGKFGYIIMKGDAM
IGARREFLDPIEMADYNGNLVKVLSVTGAFRKLQMALDQVIDQVKAGKKGAEIALPKLVV
TSDKAVDGEFTNPYALAKARAAYEIASAVAMVNVKGCFMTKEWEKYIPIVCSAHEMMRVA
AVLCDEARELEKACDGVIRKPHKKDGVIVAKTKLISKPE
>B9AFI6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter smithii DSM 2375|TrEMBL
MVVKIGIIKSGNIGTSPVLDLLLDERADRPNIDVRVFGSGAKMNPEQVEDVVPKVDQFDP
DFCIFISPNPGAPGPAKARELLSEKDIPAIIIGDAPGKGKKDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNADILKVLAETGALRLVQNTIDGVIDGAAAGNIELPKLIITAEKA
VEAAGFENPYAKAKAIAAYEMAGAVANLDMKGCFMTKGFENFIPLVAAAHEMAASAAALA
DEAREIEKGNDSVLRTPHMKEGNTGRKTDLISKPE
>A0A842RK55|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Heimdallarchaeota archaeon|TrEMBL
MTQKEGQQTRTKIGILKLGNIASSILLEMLLDERADRLDIDVKTVSSGAKLEEGSVLEAV
EAFLTLKTELILVATPNASLANAQKAIEKVAKTGKPTIVITDTLKKKTQESFDNQGIGYL
VVKADAMIGARREFLDPIEMTLYNSDILRILAIGGVFTIIYQEINKVVHQIQQGTKTILP
QIEIDSESAVKTAGFANPYAEAKARGALEIAEQVGKLNLEACFRVNERFRYIPMVAMGHE
MIHSAGKMADDAREIEKGENKVRRKPHSYEGDIQDKRLLTEKPR
>A0A524MEI3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thorarchaeota archaeon (strain OWC)|TrEMBL
MSDITRIGILKIGCIGAAPLIDLILDERAERKDIAV
>A0A811TC93|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Argoarchaeum ethanivorans|TrEMBL
MGNIGTSLAIDLLFDEIAEREDINTRTFSSGAKMGKEEADDTKHFKRWYPDLLIMVSPNP
NMQGPAEARRIWKDVPTILVSDGPTKKDERQKLADAGFGYIILPVDPLIGAKREYLDTVE
MVNFNSEVNKTLAFTGAIRLVQETIDGVIEEIKAGETLNLPHILAKPEKCIEYGGFSNSY
AKAKALAALHVLLKAAEINSKACFGMKGIEAITLTTAAGHEMVRTASMLADEAREIEKCN
DTVSRKPHARDGRILSKTRLYEKPE
>A0A842U5S8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MSESKVLKIGVHKNGTIGSSVLLSFLIDERAEAERLVFREVTSGPKMHPPEECVTTMNKL
LEFEPELILMSSPNAALKGPKAARELVGNTPTIVISDAPAKKAIEEFKEKNMGYIIVGCD
SMIGARRPFLDPIEMSIFNADLLKVLAITGAFNIIVNELNKVIMDMLEGKTPTLPQIEIN
AENATQAAGFSNPYARAKAIAAFELASQVSKITGRACFVLKEREKYMPLLAASHEMMRTA
SLMCDKAREIEKSNDTVLRTPHHAKQHILSKRALHEKEK
>A0A7C4S5S1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Geoglobus ahangari|TrEMBL
MVKVGVLKMGAIGTALLVEYLLDERADREDIEVRVITSGAKMQPEEAKIAEKLKEFDPDV
VIVVSPNAALPGPKAAREAFEGKPVIVISDAPAKKAKEELEQKGFGYILINADSMIGARR
EFLDPTEMALFNADVVKVLAATGAFRIVQEEIDKVIEAIKKGEKPELPKIVVTAEKAVAA
GNFQNPYAKAKAMAAYYIAEKVADINVKGCFIEKDPDKYIPLVASAHEMMRVAAILADEA
REIEKSNDTVYRNPHARDGTILKKFKLMEKPQ
>A0A662RCN7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MSDVKIGFVKLGNLGMSQVIDLILDEIAARQGIAVRTLGTGAKMGADEAADTKALIEHWD
PDFVVMISPNAGAPGPTAAREVYKDTPTIIVSDGPDKKDARLALKEAGFGSIILKVDPLI
GAKREFLDPTEMASFNSDAMKVLSACGPVRLIQEEFDKVIDQVAAGKSGKDLELPYILAT
PDKCVERGCFENPYAKAKALAALHMANTVAAINFPACFMLKEVEKVSLVAAAGHEMMGAA
AVLAREAREIEKSNDTLFRQPHAKAGNLLTKTKLYDKPA
>A0A2E4HPI9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thaumarchaeota archaeon|TrEMBL
MVVKITVVKSGFIGVTTLIEALLDERAARKDISVHSISSGSKMHTEASEDLEKNALLYDT
DFFILVTPNASLDAPKELAFNLSKHKPTLVVSDNPASKSINDFSNENLGYIVVQGDPLIG
IRQEFLDPIEMSNFNSDVLKVLSITGAFRALVHEIDLVVSAINNSQPIVLPRIIVDKHKA
LSHSGLSNPYAKSKALASYEMAKLVGRLSAEGGYKEKDRQKYLLVVSASHELIRQAAIXA
DEAREIEKTHDNVFRQIHDSEGNYATKNKLLDSF
>A0A2P5K0I8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|ANME-2 cluster archaeon HR1|TrEMBL
MVKIGFIKLGNLGMSQVVDLILDEIAAREGIDIRVFGTGAKMGKDEAADTEKFKMYNADF
YVIISPNASAPGPTAAREIWKDRPMIVISDGPTKKDDRKALEDAGFGTLVLKVDPLIGAK
REFLDSVEMASFNSDAMKVLSTCGVVRLIQVEFDKVIDQVNAGKSGKDLELPHILISAQK
AVESAGFNNPYAKAKALAALHMADKVAEINFPACFMMKDIKDVTLTTATGHEMMRAAAQL
AIDAKEIEKANDTVYRQPHAKKGNLIEKTKLYDKPQ
>A0A1V4UPF2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosaeta sp. PtaB.Bin018|TrEMBL
MLARQKRKPFYLLLTLKHRMFKIGFVKLGNIATSTAIDLALDEIAERTDLEFKIISFGPK
MTKKEGEASAELKAWGPQLVVVSSPNAATAGPTSAREQFKGLPTIVISDGPTKKEARDAL
AAEGFGYIILPVDPLIGAKREFLDPSEMALFNSDALKVLAACGAIRLVQEELDKAMTSIA
SGEPKLPAILATPEKCAERMNFSNPYARAKAVAALYMAQTVATIDATACFRLKELEAIAL
MAAAGHEVMRAAGRLADESREMEKANDSVSRKPHARTGELMAKTRLLEKPGKI
>A0A843GA14|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter sp|TrEMBL
IIVMADPMIGAKREWLDPTEMAIFNADIIKVLAETGALRLVQKTIDGVIEAVEAGNEIEL
PKLIVTAEKAVEAAKFQNPYAKAKAIAAYEMAGAVAGLDMKGCFMTKGFENFIPLVAAAH
EMAACAAALAAEAREIEKSNDTVLRTPHMKEGNVGCKLDLISKPE
>A0A7G9YJ96|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon ANME-2c ERB4|TrEMBL
MAKIGFIKLGNLGMSQVIDLIQDEIAAREGIEIRSLGTGPKMGKDEAAETEYLKKMDADF
YVMISPNSSAPGPTAARELYKDVPCIVISDGPTKKDDRKALEDAGFGYIIMTVDPLIGAK
TEFLDPVEMASFNSDAMKVLSTCGVVRLIQEAFDDVAAQADAGKSGKDLELPHILAKPEK
CIESAGFANPYAKAKALAALHMADKVAQINFPACFMMKEIEQVTLTTATAHEMMRASAQL
AIDAREIEKSNDTVFRQAHSKKGNIVRKTKLYEKPQ
>A0A832TZM3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMSPAEAAASESFKQWNADF
VIIISPNAAAPGPTAAREIWKDVPCIVVSDGPTKKEAREALEKDGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLIQEELDKVTDQVASGKSGKDLELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
ATQAREIEKSNDTVFRQPHAKNGTLLKKINLYQKPE
>A0A1D2UXM7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanohalophilus sp. 2-GBenrich|TrEMBL
MGNLGMSQVIDLVQDEIAAREGISTRVFGTGPKMDKETAASTDELKAWEPDFVVMISPNA
SAPGPKSARELWNDYPCIVVSDGPTKKDDRQALEDAGFGYIIMTVDPLIGAKTEFLDAVE
MASFNSDAMKVLSTCGVVRLLQEELDAVTAQVDEGKSGADLELPHILAKPQKCIERAGFN
NPYAKAKGLAALHMASKVAEVNMPACFILKEIEDVALTAAAGHELMRAAAQLAIEAREIE
KANDSVFRQPHSKKGAQLQKIKLYEKPQKV
>A0A3N5N791|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoregulaceae archaeon|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLEPADVDRVVSNLKAYKP
DFCIVVSPNGVLPGPTGAREQLAAAGIPVVIITDDVTTKKEWEGVKASKFGYIIMKADSM
IGARREFLDPVEMSDYNGNLVKVLALTGAFRKMQVALDKVIDQVKAGKSGDAIELPKIIM
TTDKAVDGEFTNPFALAKARAAHEIAIAVAGQNVKGCFMTKEWEKYIPIVASAHEMMRVA
AALCDEAREIEKAGDCILRQAHKKDGTLVRKTKLVAKFD
>A0A1G5W903|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter millerae|TrEMBL
MVVKICILRSGNIGTSPILDLLLDERADRPNIDVRVFGSGAKMNPEQVEEVVPKLEQFDP
DFCIFVSPNPGAPGPAKARELLSEVDIPAIIIGDAPGKGKKDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNADIIKVLAETGALRLVQKTLDGVIAAVEAGEEVELPKLIVTAEK
AVEAGEFANPYAKAKAIAAYEMAGSVANLDMKGCFMTKGYENFIPLVAAAHEIAAAAAAL
AGEAREIEKGNDTVLRTPHMKEGAVGRKTDLISKPE
>A0A151BPS8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon B26-1|TrEMBL
MPETVKVGIVKAGCIGVLPLIEILLDERADRTDIDVRVVGSGAKLGLEQCQEVTDIMIKQ
KPDLAILVGPAQAAPGPTEARRMLAEAGIPTVVISDSPAKKLTKEMEDAGLGYIIVEADS
MIGARREFLDPTEMALYNSDVIRVLAATGVLSLIVREIDRVIDSLKKGEEPVLPRLIIDK
GLVASNFKNPYAGAKAVAAYEIARNVARLNTEACFKVKEWTVYTQLAASGHEMMRAAAQL
ADEARELEKSGDSVLREPHFRDGTLGEKRSLIEKPKKKAPSP
>A0A7K4IJC1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Nitrososphaerales archaeon|TrEMBL
MVVKVGFVKIGNIGAAPLLELLLDERAERQDIEVRVHTTGAKMAPEQAEEVSRRMVDHKP
DFVVTASPNAALPGPSKIREVMTGAGIPVIVVSDSPAKKATKQMEELGQGYMIVEADSMI
GARREFLDPIEMALFNADLMKVLSITGAFNILCNEMDKVIDAFKKGEKPSLPRIVIDKEK
AVNASGFQNPYARVKAMAAYEIARKVADLDVEGCFMVKEWERYTSLVAAAHEMMRTASIL
ADEAREIEKNGDTVIRMPHHDDGTILQKRKLIEKPKKPGE
>A0A532T5Q6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon Loki_b32|TrEMBL
MLKIGMLKNGTIGSSLLLAFLIDERAEATRVNVREVTSGAKMHPADHCLETMKKLLEFEP
DLIVMSSPNAALPGPKATRELTGNIPTIVISDAPAKKAIDEIKAKGMGYILVNCDSMIGA
RRPFLDPVEMSIFNSDLLKVLAITGALQIIAEELNKVIMDMLEGKSPVLPQIIIDANIAT
EAAKFSNPYARAKAIAAFELAASVSKVTAKACFQLKERSEYMPLLAAAHEMMRTAALLCD
EAREIEKSNDTVIRRPHHAKKQRFLSKIGLYDKEQ
>A0A7C3WRN3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MPVKIGFAKLGNIGSAPLIEFLLDERAEREDINVRVVSSGAKMNVEEATEVAEKLLEFKP
DLAIVVSPNASLPGPEKAREILNKAGIPVLVVSDVPAKKAVKKLEEGGFGYLIVEGDPMI
GARREFLDPIEMALFNAEVIKVLAGSGAFNILFTEIDKVIEALKKGEKPQLPKKIIDSEA
AAEAAEFQNPYAKAKAQAAYEVAKKVAEMNVQACFVIKDWQKYTALAAASHELIREAAKL
IDEAREIEKTSDSVVRHPHYDDGKILSKRHLIEKPR
>A0A7J2IS13|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MEGQIVKIGVVKCGNIATAPLIEFLFDERADREDLDVRVVGSGAKMGPAQAEEVAKKILD
FNPDLVIIISPNAALPGPSKAREILAQSNIPTIVISDQPGKKAVKDIEGKYMGYFIIPAD
AMIGARREFLDPIEMAIFNADLIKVLSVTGVFSIVYREIAKVIDQIKKGEKPELPRIIID
KETAVKAAGFQNPYALAKAMAAYEIARNAASLTVEGCFVIKEMERYVPIVAAAHEMIRIA
AALADEAREIEKYGDYLLRMPHHKTGE
>A0A7J3F9M3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MIKVGILKAGCIGSLPLIEFLLDERAEREDLQVRVVGSGAKVTVDECIEIARQILEQNVD
LIIFVGPAQTTSGPSEARNLLKNSGKPTIIISDSPAKRIVKNLEEDGFGYIIVMGDPLIG
ARREFLDPTEMAIFNSNIIKVLAITGIYKIMLQEIDRVIYELKKDLTPKLPRLILDSDEI
MERSDFKNPYARAKAMAAYELTKKVAEINVRACFTEKEKEKYIPLVACTHEIAQAAARLA
EEAREIEKYSDTLIRRPHSKEGKLGVKEKLMEKPVYD
>A0A842MPQ1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKVGIFKCGNIGTAPLLELLLDELADRTDISVQSVTTGAKMLPQEVEEALPKIFDFNPDF
LIFISPNPAVKGPARAREILLEKGMPSIFISDSPGKRLKEEFEKAGFGYIIVMGDPMIGA
RKEFLDPTEMAIFNANVIKVLAVTGVYRIVQQEIDRVISFYKEGLTPEFPRLILDTDVIM
TRSDFKNPYAKAKAIAAYELMKKVAEINVKACFMEQNKEKYIPLVASSHEIVQIAAKLSE
EAREIEKYSDTLTRRPHAKDGTLKIKEKLMEKPLTDDEIYKNWFKAISKNSQEN
>A0A843CAE9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MEQKKNIKIGIFKCGNIGTSPLLELLFDELADRKDIKVRTVTTGSKMGLEDVEESLPKLF
ELNPDFLILISPNTALPGPAKAREKISNSGLPGVIITDAPGKKVKSELANQGLGYIIITG
DPLIGARKQFLDPIEMALFNSNISKVLAITGAYRIVQKEIDKVVYALEIGEKPVLPQIIV
SLKSIRDESEFSNPYAKAKAMAAYALAEKIAEINTLACFIEKESQNYIPLVTCAHEIAQA
SARLAEEAREIEKCNDTLMRKPHSKSGKTKIKTKLMFPPIFEEEC
>A0A497K8L2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MGCLGSVPLLEFLFDERAERTDLDVRVVGSGAKLGPEQCVEVTKTLLNLKPDFIIVAGPA
QQTAGPKEARKLLADSGIPTLIISDGPMVRIKGELEKAGFGYIIVEADPMIGARREFLDP
VEMAIFNSDVIKLLACTGVFNVIVDAVDRIIESLKRGEKPSLPHIVVDRNLALKAAEYSN
PYARAKALAAFDLAKQVTSLHVEACFKLTDWKEYTLLVAAGHEAVRLASKLSEEAREIEK
ASDSVLRRPHHRDGVRSRKRALIEKPKKD
>A0A497KBD2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MRIGVVKCGNIGTAPLFELLLDELADREDIIVRSITTGSKMIAETVEEALSSMFDFAPNL
IIFISPNPAVRGPKRAREILSEKNIPCIFISDAPGKRLREEFEKLGFGYIIVMGDPLIGA
RKEFLDPTEMAVFNSNIIKVLAITGVYNIILREIDRIIHNLKENLIPELPKLIIDTGEIR
DKSDFKNPYAKAKAMAAYELAKKIAEINTKACFIEKEKEKYIPLVACAHEIAQVAARLAE
EAREIEKHSDVLIRRPHARDGKPKIKQRLMEKPVFDEETYQEWFK
>A0A0E3QAP5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp. Kolksee|TrEMBL
MVNIGFIKMGNLGMSQVINLLQDEIAAREGITVRVFGTGAKMSPAEAAASESFKQWDADF
VIIISPNAAAPGPKAAREIWKDVPCIVVSDGPTKKEAREALEKEGFGYMILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLVQEELDKVTDQVASGKSGKELELPHIFAKPEK
CVEYAGFENPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
AIQAREIEKSNDTVLRQPHAKNGTLLKKVKLYQKPE
>A0A0E3WQ66|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina mazei C16|TrEMBL
MKKMVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMAPADAADTESFKQWN
ADFVVIISPNAAAPGPTAAREIWKDAPCIIVSDGPTKKEAREAFEQEGFGYIILPVDPLI
GAKREFLDSVEMASFNADAMKVLSICGVVRLIQEELDKVTEQVASGKSGKDLELPHIFAK
PEKCVEHAGFANPYAKSKALAALHMAEKVAQVNFPACFMLKEIEQVCLTAAAGHEIMGAA
AQLANQAREIEKSNDTVSRMPHAKNGAVLKKVRLYEKPE
>A0A368TCM2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanophagales archaeon|TrEMBL
MQVVKIGFVKLGNIGASRIVDLLLDERADREDIDARVMGTGAKMTPEHAADTSRLLDWDP
DLVVITSPNAALPGPKRAREMVKEKGKPCIVISDAPAKKAVNDLKENGYGYIIIPGDPMI
GARREFLDPVEMSLFNADVLSVLTIAGVVNLLQEELDAVIDAIKKGGDVKLPQLIATAEK
SVERAQFSNPYAKSKAIAAYSMVEKVAELDVKGCFMMKDPKEYVPIVAAAHELLREAAKL
AYEAREMEKQTDSLVRMPHARTGEILKKVKLQDKPSA
>A0A2R6T814|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|archaeon SCG-AAA382B04|TrEMBL
MKLGIAKLGHIGSSFVDKLLDERAEREDLDVFCIGSGSKMDPCSSKEVIKKLFETNCDAY
IVVSPNPSTPGSREALEKIEEIEEPIVIIGDVAGKEVREDLEKWGFGYIFVYGDALIGAR
KEFLDPVEMADFNSNVLKVLSLTGVFRKIVSETDRLIDSVKKDSNYLPKDILEPNKIVSE
EFENPYARAKARASLEISQNVAILNQKACFKLDNRDEYLPLVVATHEMMEKASELAKEAR
EIEKTNDNVLRKPHDYDGGFLEKRELFEEFKK
>A0A847V955|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanospirillum sp|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLEVADVDRVVSTLKAWGP
DFCIVVSPNGVLPGPTGAREQLAAAGIPVVVITDDVTTKKEWADLKESKFGYVIMKADSM
IGARREFLDPIEMADYNGNLVKVLAITGAYRKMQLELDKVIDQVKAGKKGADIALPKVVM
TADKAVDGEFTNPYALAKARAAYEVASAVAMVNVKGCFMTKEWEKYIPIVSSAHEMMRAA
AVLCDEARELEKAGDGIIRQPHKKDGVIVSKTKLISKPE
>A0A1Q9MWZ9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Lokiarchaeota archaeon (strain CR_4)|TrEMBL
MRVVKVGVVKNGNLGACPVLDLIFDERADRDDVDFRVLGSGAKLGKVQCIETMDKMLEFK
PELIIMISPNAALPGPKEGRDKIKDIPTIVYSDMPAKKAVEEFESKGIGYILCGADSMIG
ARRPFLDPVEMSLFNADLLTVLSITGVINCIQDEIDGAIAAIKTGVKPKLPKLVIDMEIA
SKYAKFSNPYAQAKSMAAYEIASRVAAIDVKGCFQVKEKEQYMPLLATAHEMMRVASRLA
WEAREIEKVNDKVLRRPHHREGQILSKRGLMQKEE
>A0A6N1YFT7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|methanotrophic endosymbiont of Bathymodiolus puteoserpentis|TrEMBL
MKKLLFQFDTDTHPSVFDSVVAYDGGADHVIGHGNLTPENVRALVEGTIFTRPPKDKKNT
AIFVGGSDMAAGQVLFNAVRSYFFPGFQVSVMLDSNGSNTTAAAVVAKLASSGTLIGKQA
VVLAGTGPVGQRAAVMLAEEGAHVTIVSRSLANSEKACLTMKERFNVDLSAAEASDSDAR
GDAIKNANIVLATGAAGIELLKPEHWQNNPNLEMLADANATPPIGIGGTDMLDKGIDRHG
KIIWGAIGFGAFKLALHRACIARLFEDNKQVLDAELIFKLAKEMA
>A0A842YQL4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermobacter thermautotrophicus|TrEMBL
MVVKIGIIRCGNIGTSPVLDLLLDERADRPNIDVCVVGSGAKMNPDEIERAVPSMLEMDR
DFVIFISPNPGAPGPAKARELLSEADVPAMIIGDAPGLRVKDEIEEQGLGYIIVKADPMI
GARREFLDPTEMASFNSDVIKVLAFTGAYRVVQNTIDAMIADVEAGKAPELPQVVIDTDV
AVEAAGYENPYAKAKAMAAYEIATKVADIDVKGCFMVQDPDKYIPIVASAHEMLAAAAKL
AAEAREIEKANDTVLRTPHGKEGETLSKTDLLAKPE
>A0A523B262|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Nezhaarchaeota archaeon WYZ-LMO8|TrEMBL
MSQQAPVKVGIIKLGCIGCAPLLEYLLDERADRNDISVRVVSSGAKMTPQEAEEVVKMLE
PFKPQLIIIASPNAALPGPTRAREVAKLLNVPTLIISDAPARKAVSKFEEGGFGYIIVEA
DSMIGARREFLDPTEMALFNADIIRVLAITGVFNLIVKTIDDMIASIKKGEEVKLPRLIV
TKEIALENAGFSNPYAYVKAMAAFEAARKVSDLTTEGCFKVQEWEKYIPLVAAGHELMRY
AAKLSDEAREIEKGLDQVMRMPHRASGELSVKRKLIEKLPPKA
>A0A7J2QXM7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|archaeon|TrEMBL
NGTIGSSLLLAFLMDERAESTRINVIEVTSGAKMNPSGYCVETMEKLLKIEPELIIMSSP
NAALPGPKATREMTGNIPTIIISDAPAKKAIEEIKEKNMGYILINCDSMIGARRPYLDPI
EMSVFNADLLKVLAITGALQVITVELNKVIMDMLEGRTPTLPEIIIDSNRATEAAKFSNP
YARAKAMAAFELAASVSKITGKACFQLKERSDYMPLLAAAHEMMRTAALLCDDAREIEKS
NDSVIRRPHHAKQHLLKKIRLYDKEQ
>A0A832YTE3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermococcus okinawensis|TrEMBL
MVVKVGIIKCGNIGTSPLVDLILDERADRKDIDVRVLG
>A0A662U889|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thermoprotei archaeon|TrEMBL
MSAEEKVVKIGIIKPGAIGTSVILEYLLDERADRRDIDVRVYGTGAKMVVDENLLKAAIE
ANHDLYIVTAPANVKIIKKIAKKLKEAGKRVIIISDEPTKKAAKDFEAEGYGYILVYGDP
MIGARREFLDPTEMALFNSYVLGVLSATGALRIVTEAIDKVVEALKKGEEPELPKLKIDK
NAIERQGGFTNPYAKAKAIAAYEIARRVASLTTEACFVIQEPERYIVIAAAGHEMLKAAA
RLAEEARDLEKSEDTVLRTPHHPTGRTLSKAKLLEKPR
>A0A2P0QL26|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon|TrEMBL
DVTTKKEWEGVKASKFGYIIMKADSMIGARREFLDPVEMADYNGNLVKVLALTGAFRKMQ
IALDKVIDQVKAGKKGDAIELPKVIMTTDKAVDGEFTNPYALAKARAAHEIAMAVAGQNV
KGCFMTKEWEKYIPIVASAHEMMKVAA
>M5DYM5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Halanaerobium saccharolyticum subsp. saccharolyticum DSM 6643|TrEMBL
MKKLLIQLDTDKRASTFDQVVAYDAGADKLIIHSGITKEEVEDIIYGAIFTRSPKKMKNT
AVFVGGSDVEKGEEILKAVEDVFFANFRVSVLLDSNGSNTTAAASVLKVKREISLEGTEV
LILAGTGPVGVRAAALFAMEGASVTITSRSQEKADRKAEMIMEEYALENIKGVEANTDQD
FIKAMKNKEVILSAGPPGINFISKDMWENEENIKVMADINAVSPAGIEGIEPNADGETLD
GVKIFGALGIGGLKMKLHKKAVAELFKSNDKILNAVEVYKLNEKL
>A0A166CS26|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter cuticularis|TrEMBL
MVVKIGIIKSGNIGTSPVLDLLLDERADRPNIDVRVIGSGAKMNPEQVEEVTPKIKEFNP
DFAIFISPNPGAPGPAKARELLSSYDIPALIIGDGPGMGKREEMDEQGLGYIIVKADPMI
GARRELLDPTEMASFNSDVIKVLALTGAYRTVQNAIDGMIADVEAGKDVELPKIVLSRDV
AVKAADFKNPYAKAKAMAAYEIATKVADIDTEGCFMVQDAEKYIPLVASAHEMIAVAAKL
AEEAREIEKSNDTVVRTPHSGKGTTVSKTKLLDKPA
>A0A7C6AH45|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Nitrososphaeria archaeon|TrEMBL
MVKITFLKIGFIGTTPLIEALLDERASRKDLSVRVVSSGCKMEEDEAMDVSRIASSIESD
LYIIISPNAGLPGPSTARRALKETGKPIIIISDDPSRKIVKTLEEEGSGYLIISADPMIG
ARQDFLDPVEMAIFNSDVIRVLAVTGVFRLIHTEIDRVVEQIAKGDKPDLPKIVIDKEVA
LSYSGISNPYAKSKALASFEMAKRVAALSTEGCYKVEERERYIPLVAAAHEMMRTASLMA
DEAREIEKYNDSVTRVVHYRSGYTKRKTRLMDRFE
>A0A223ZHE4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermobacter sp. EMTCatA1|TrEMBL
MVVKIGIIRCGNIGTSPVLDLLLDERADRPNIDVCVVGSGAKMNPDEIERAVPTMLEMDR
DFVIFISPNPGAPGPAKARELLSEADVPAMIIGDAPGLRVKDEIEEQGLGYIIVKADPMI
GARREFLDPTEMASFNSDVIKVLAFTGAYRVVQNTIDAMIADVEAGKAPELPQVVIDTDV
AVEAAGYENPYAKAKAMAAYEIATKVADIDVKGCFMVQDPDKYIPIVASAHEMLAAAAKL
AVEAREIEKANDTVLRTPHGKEGETLSKTDLLAKPE
>H1L1K4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanotorris formicicus Mc-S-70|TrEMBL
MAAFTIAEKVGDVDVKGCFMVKEMERYVPIVASAHEMVRYAAKLVDEARELEKAMDAVSR
KPHHPEGNVLGKKKLMEKPE
>W9DRW4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanolobus tindarius DSM 2278|TrEMBL
MAKIGFIKLGNLGMSQVIDLVQDEIAAREGITVRVFGTGPKMGKDEAAATEELKKFDADF
YVMISPNSSAPGPTAAREIYKDVPCVVISDGPTKKDDRAALEEAGFGYIIMTVDPLIGAK
TEFLDPVEMASFNSDAMKVLSTCGVVRLIQEELDKLAAMADEGKELELPHILAKPEKCIE
RAGFNNPYAKAKGLAALHMADMVAKINFPACFMMKEIEQVTLTTAAGHEMMRAAAQLAIE
AREIEKANDSVFRQPHSKKGNLMTKTALYEKPQ
>A0A2P0QMJ9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured bacterium|TrEMBL
HMLDPMSTNSPFDVNMAMDAGFDVLMPYSNVKLDSINRLTQDVIFSRSPAGIKRTGMFIG
GRDLGLAVDMLDACRQAMVPPFEVSVFADPSGAFTTAASLVACVEKELKTKHGKELKDCK
ALVFGGTGPVGIATGIIASLAGADTVLVDHLSSEAAAEVAKTYNRRFGCALTGICANTDD
DKINLVATADIIFSAAKAGVQVLNSFVLKDARQLKVAGDINAVPPMGIEGIKRSDLGVSL
AHAINSKGAVGIGALAVGNVKYQLQHNMLKSMLETEIPLFLDFRAAFTKARE
>A0A523AIB3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobi archaeon|TrEMBL
MSKVKVGVLKMGAIGTAVILEYLFDERADREDIEVRVVTSGAKMQPEEAVVAEKLKEFNP
DLIIVASPNAALPGPKAAREAFAGKPVIVISDAPAKKAKDELKEKGFGYIFINADSMIGA
RREFLDPTEMALFNADVLKVLAATGALRAVQEAIDKVIEDIKAGKKPELPQLIITAEKAV
EAGKFSNPYARAKAIAAYYIAEKVSDLTTRGCFVEKDYNVYVPLIAAAHEMMRVAAILAD
EAREIEKYGDKVYRNPHARDGKVLSKVELISKPQ
>A0A497GRP8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thermoprotei archaeon|TrEMBL
MGLWNMPKVRVGVLKIGCIGCTPLLEYLLDERADREDIEVRVVGSGAKMTDEDVEDVVKG
MLNFNPSFVILTTPNATLPGPKKVVELLTNAKLPTLVISDAPAQKARKYLEEKGAGYIIV
LADSMIGARREFLDPVEMAIYNSDVIRVLAITGVYNILYEAIDSIIEALKTGKELTLPRI
VVNAETAVNKAGFGNPYAKAKAMAAFEIAATVSKLTTAACFKIKERERYIFYAAAAHEMM
RYAASLADEAREIEKYGDHVVRRPHSKEGVILHKTRLLEKPLK
>A0A662S978|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Korarchaeota archaeon|TrEMBL
MVRVGFVKLGNIGCAPLIEFLLDERAEREDISVRVIGCGAKMNPEDAEEISKKMLEFKPD
FVVITSPNASLPGPTKAREILAQSVPVIVVSDLPAKRIVSELEEKGIGYIIVEADAMLGA
RREFLDPIEMALFNADLIKVLSITGVYNILFESIDKVIEAIKEGKKPELPKIVVKAKKAI
KAAGFSNPYAASKAMASFEIAKNVADVTVTACFKEKDWEKYTLLCSAAHEMMAEAAKLAS
EAREIEKSADKVLRKPHYDDGTILIKRALIEKPSKPE
>A0A7J9NZI8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcus maripaludis|TrEMBL
MVVKIGILKCGNIGMSPVVDLCLDERADRNDIDVRVLGSGAKMGPEQVEEVAKKMVEEIK
PDFIVYIGPNPAAPGPKKAREILSAGGIPAVIIGDAPGIKDKDAMAEEGLGYVLIKCDPM
IGARRQFLDPVEMAMFNADVIRVLAGTGALRVVQNAIDDMVFAVEEGKEIPLPKIVITEQ
KAVEAMDFANPYAKAKAMAAFVMAEKVADIDVKGCFMTKEMEKYIPIVASAHETIRYAAK
LVDEARELEKATDAVSRKPHAGDGKILNKCKLMAKPE
>A0A8A3S5L7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanofollis aquaemaris|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVVNMKAWEP
DFCVVVSPNGILPGPTGAREQLAEAGIPCIVITDDVTGKKEQFAALKESQFGYIIMKADS
MIGARREFLDPVEMADFNGNLVKVLALTGAFRKLQFELDKVIDQVKEGKKGADLVLPKVV
MTSDKAVADEFSNPYAYAKARAAYEIAQAVAGVNVKGCFMTKGFENYVPIVASAHEMMRQ
AAYLCDEAREIEKAGDGIIRKPHKKDGVIVSKTTLISKPE
>A0A8D4VHD7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoculleus chikugoensis|TrEMBL
MVVKVGIAKLGNIASGVMGELLLDERADREDMITFMATSGTKLQPEDIERVVSNMKAWGP
DFCIVVSPNGVLPGPTQAREDLAAAGIPCIVITDDVTTKKEQFEALKASNFGYIIMKADA
MIGARREFLDPIEMADYNGNLVKVLAITGAFRKMQVELDKVIDQVKAGKKGADLVLPKVV
MTSDKAVDGEFSNPYALAKARAAYEIAQSVAGVNVKGCFMTKEWEKYIPIVSSAHEMMRQ
AMILCEEARDLEKAMDGVIRKPHKKTGEIVSKTALISKPE
>A0A3N5B675|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter gottschalkii DSM 11977|TrEMBL
MVVKIAIIKSGNIGTSPVIDLLLDERADRPNIDVRTFGSGAKMNPEQVEDVVPKIDAFEP
DFAIFISPNPGAPGPAKAREMLSEKDIPAIIVGDAPGKGKKDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNSDILKVLAETGALRLVQQTIDTVIEQAEAGEIELPKLIVTAEKA
AEAGGFANPYAKAKAIAAYEMAGSVANLDMKGCFMTKGFENFIPLVAAAHEIAACAAKLA
QEAREIEKANDTVLRTPHMKEGNLGSKTDLISKPE
>A0A1D2WFK9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp. A14|TrEMBL
MVNIGFIKMGNLGMSQVINLVQDEIAAREGITVRVFGTGAKMSPAEAAASESFKQWDADF
VIIISPNAAAPGPKAAREVWKDVPCIVVSDGPTKKEAREALEKAGFGYMILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLVQEELDKVTDQVASGKSGKELELPHIFAKPEK
CVEYAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAASQL
AIQAREIEKSNDTVFRQPHAKNGTLLKKVKLYQKPE
>Q648F7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon GZfos3D4|TrEMBL
MEIVKIGFVKLGNIGISRIVDLLLDERADREDIDVRVLGTGAKMTPENAADTSRLLDWDP
DVVVITSPNAALPGPKSAREMVKEKGKPCIVISDAPAKKAVDKLKEGGFGYIIIPGDPMI
GARREFLDPVEMSLFNADVLSVLSITGVAKLVQEEIDAVIEAIKKGEEVKVPQIIATAER
AVERAKFSNPYAKAKAIAAYSMAEKVAELDVKGCFMMKNPEEYVPVVAAAHELLREAAKL
AFEAREVEKQTDSLVREPHSRTGEIMKKEKLMEKPSA
>A0A833DUC4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus profundus|TrEMBL
MVKVGIFKMGAIGTAILLEYLLDERADREDIEVRVITTGSKMREGDAKVGEKLKDFNPDL
IIIVSPNASLPGPKIARELFKDKPVIVISDAPARKIVNELEREGFGYILITADSMIGARR
EFLDPTEMALYNSYILNVLAITGALRLVQEEIDKVIAQIKEGKKIELPRIIVTADKAVEA
GRFSNPYAKAKAMASYYIAEKVADITTKACFIEKDAKKYIPMVCAAHEMMRIASKLAEEA
REIEKGNDSVFRNPHAKDGEILSKIKLMDKPT
>A0A1G5VBG7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter millerae|TrEMBL
MVVKICILRSGNIGTSPVLDLLLDERADRPNIDVRVFGSGAKMNPEQVENVVPKLEQFDP
DFCKFISPNPGAPGPARAREILSEADIPAVIIGDAPGKGKKDEIEEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNADIIKVLAETGALRLVQNTIDDMIAAVDAGKEIELPKLIITAEK
AVEAGGFENPYAKAKAIAAYEMAGAVANLDMKGCFMTKGFENFIPLVAAAHEMAACAAKL
ADEARDIEKSNDTLLRTPHMKEGETGCKRCLISKPE
>A0A315XKK2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter thaueri|TrEMBL
MVVKIAIIKSGNIGTSPVIDLLLDERADRPNIDVRTFGSGAKMNPEQVEDVVPKIDAFEP
DFAIFISPNPGAPGPAKARELLSEKDVPAIIIGDAPGKGKKDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNSDILKVLAETGALRLVQKTIDAVIAQADAGEAIELPKLIITAEK
AAEAGGFANPYAKAKAIAAYEMAGSVANLDMKGCFMTKGFENFIPLVAAAHEIAACAAKL
AQEAREIEKANDTVLRTPHMKEGNPGCKTDLISKPQ
>A0A831LC37|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoculleus sp|TrEMBL
MVVKVGVAKLGNIASGVMVELLLDERADRQDMQTFMATSGTKLEVEDVDRVVSNLIAYKP
DFAIVVSPNGVLPGPTGAREALKAAGIPVIVITDDVTTKKEWADLKESDFGYIIQKADAM
IGARREFLDPCEMADYNGNLIKVLTVTGAFRKMQIAIDAVIDQVKAGKAGADLELPKIVM
TADKAVKDEFTNPYAYAKARAAFEIAAAVAMVNVKGCFMTKGFENYVPIVASAHEMMRAA
TVLCDEAREIEKGCDGVVRMPHKNDGTIVSKTTLISKPE
>A0A1V4YQR2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium sp. PtaU1.Bin242|TrEMBL
MVVKIGVIKCGNLGTSPVIDLVLDERADRPNIDVRGVGSGAKMNPEQIEDAVPKILDFDP
DFVVFISPNPGAPGPARARELLSEMDVPAIIVGDAPGMGKKDEMDEQGLGYIIVQGDPMI
GARREFLDPTEMASFNSDVIKVLAATGAYRKVQETLDAAIAQAESGSIDLPKVVISTEVA
VTAGGFQNPYAKAKAMAAYEIAMKVADVDLKGCFMTKEMEKYIPIVASAHEMISAAAKLA
VEAREIEKANDTVLRKPHGGQGQTLSKTELMLKPE
>Q64AB6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon GZfos32E7|TrEMBL
MQVVKIGFVKLGNIGASRIVDLLLDERADREDIDARVLGTGAKMTPEHATDTSRLLDWDP
DLVVISSPNAALPGPKRAREMVKEKGKPCIVISDAPAKKAVNDLKENGYGYIIIPGDPMI
GARREFLDPVEMSLFNADVLSVLTITGVVKLMQEELDAVIDAIRKGGEVKLPQIIATVEK
SVERAQFSNPYAKAKAIAAYSMAEKVAELDVKGCFMMKDPKEYVPIVAAAHELLREAAKL
AYEARDMEKQTDSLVRMPHARTGEILKKVKLLDKPSA
>A0A7J3F2E8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MNRAVKVGVLKAGCIGSLPLLEFLLDERADREDIQVKVIGSGAKVTAEQCIECAEQVLKQ
DFDLIIFAGPAQTTQGPSEARNLLRNSNKPVIIISDSPAKRIIKELDESGFGYIIVEADS
MIGARREFLDPAEMALYNSDIIKVLAVTGALNIIVKEIDRVINTIKSGEKVILPRLIVDG
RMAVEEAGFSNPYAKAKAMAAYEIAKQVSTITFEACFKVQEPDIYIPLVAMAHEMMRVAA
RLVDEAREVEKGSDSIFRRPHFKDGALGKKRRLMEKPQRVDASN
>A0A7C5JZC1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKKVRVGIFKCGNIGTAPLLELLLDELADREDISVRTITTGAKMLAEEVAEALPKMFDFN
PDFIIFISPNPAVQGPRKAMEILLEKKVPSIFISDAPGKRLKEDFEKQGFGYIIVMGDPL
IGARREFLDPTEMAIFNSNVIKVLAITGVYKIIQQEIDRIIQCCKEGLTFELPRLIIDTD
TIRDNSDFRNPYALAKAMAAYELTKKIAEINTRACFMEKEREKYLPLVACAHEIAEVASY
LAEQAREIEKYSDTLVRRPHSKEGKLKVKERLMDSPIFEEAFR
>A0A7J2TQL6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MEKVKVGIVKCGNIGTAPLLELLLDELADREDISVRSVTTGSKMVAEDVAEVLPKMFDFN
PTFLIFISPNPAVQGPTKAREILLEKNIPSIFISDAPGKRLKEEFEKHGFGYIIVMGDPL
IGARKEFLDPTEMAIFNSNVIKVLAITGVYRMVYQEIDRLIHGYKAGLTPELPCLIIDTE
NIMDQSDFRNPYAKAKAMAAYELTKKIAEVNTRACFVEKEKEKYIPLVACAHEIAQAAAN
LAEEAREIEKYADTLVRRPHAKDGKPKVKDKLLLPPSFDEEIYQKWLKGFR
>A0A7C4FBE4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MSVKVGFLKLGNIGSAPLIELLLDERAERQDIVVRVVSSGAKGVQEVNEAEEVAKKILEF
NPQLIVITSPNAATPGPTRAREVIAPSKIPTIIISDSPAKKALKSIEDLGMGYIIVEADA
MIGARREFLDPIEMALFNADLVKVLSITGVYNILFETIDKAIAALKEGRSVELPKIVVDK
EVAVKAAGFSNPYAYAKAMAAYEISRRVADLTVEACFKVKEWERYTVINAAAHEMMLTAA
KLAEEAREIEKYSDTVVRKPHFDDGTILFKRKLIEKPTKQT
>A0A7C0V337|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
ITKERALEMSGLNNPYAYAKAMASFEMARRVAALSTEGCFKVKERERYIPIVAAAHELMR
WEAILADEAREIEKANDAVTRIVHFRDGSLRRKKKLYEKYEALTDL
>A0A497N5F8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVKVGVLKYGYVGTAPLLEYLLDEYAGREDITVRVVNSGAKLTSEEVEAAKLAMEAHEIE
KYGDYLLRIPHAKNGSLLLKLKLAEKLEKKVEGCRQCLHLHL
>A0A497KNN1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MAVSPVKVGVLKLGCVGTAPLLEYLLDERADRGDIKVRVVSSGAKLDPEEAEDVAKGILQ
FKPNFAIVVSPNAALPGPTKAREILKEAELPVLVVSDLPAKKAAKDMDAKGFGYFVVEAD
AMIGARREFLDPVEMACFNADIIKVLALTGVFNLLVKCVDGIIQAFKEGKQPELPKIVVD
KTTALKEAGYQNPYAYAKAMAAFEAARRVGDLTTEGCFKIQEREAYIPIVAAAHELMRYA
SKLAEEARETEKSEDMVLRKPHGKDGSLLSKVKLMEKPEKK
>A0A124FI53|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archeaon 56_1174|TrEMBL
MAKVGFVKLGNLGTSQGIDLLLDEIAQREGIEVRVLGSGAKMTPKEAEESAELKQWGPDF
VIIISPNAMAPGPTKAREIWSDTPTIVISDGPTKKDDRKAIEEAGFGYIIIPMDPLIGAK
RQFLDATEMISFNSDVLKVLSLTGVSRLVKEELDKVIAQVDAGKSGKELELPHILVTPEK
CTERMNFSNPYARAKAMAAAHIASKVPDLTFKACFVYKDIEDIVLAAAAGHEMMRIAAKL
AEESREIEKTLDEVSRMPHAKSGETLSKMKLYEKPQ
>A0A1V5AMQ2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosaeta sp. PtaU1.Bin016|TrEMBL
MLARQKRKPFYLLLTLKHRMFKIGFVKLGNIATSTAIDLALDEIAERTDLEFKIISFGPK
MTKKEGEASAELKAWGPQLVVISSPNAATAGPTSAREQFKGLPTIVISDGPTKKEARDAL
AAEGFGYIILPVDPLIGAKREFLDPSEMALFNSDALKVLAACGAIRLVQEELDKVMTSIA
SGEPKLPAILATPEKCAERMNFSNPYARAKAVAALYMAQTVATIDATACFRLKELEAIAL
MAAAGHEVMRAAGRLADESREMEKANDSVSRKPHARTGELMAKTRLLEKPGKI
>A0A0E3L9K3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina siciliae T4/M|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVCGTGAKMGPADAADTESFKQWNADF
VVMISPNAAAPGPTAAREIWKDVPCIVVSDGPTKKEAREALEQEGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSNCGVVRLIQEELDKVTEQVASGKSGKDLELPHIFAKPEK
CVESAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEVEQVCLTAAAGHEIMGAAAIL
ATQAREIEKSNDTVLRQPHAKNGTLLKKVKLYEKPE
>A0A7L4PVK9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon|TrEMBL
SAHEMMRCAAVLCDEARELEKAGDGIIRKPHKKDGVIVSKTKLISKPE
>A0A1V5A6Y7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoregulaceae archaeon PtaU1.Bin222|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLEPADVDRVVSVLKAWKP
DYCIVVSPNGVLPGPTGAREQLAAAGIPTLFITDDVTTKKEWAEIKDGKFGYIIMKADAM
IGARREFLDPIEMADYNGNLVKVLAVTGAFRKLQTALDGVTDQIKAGKKGAEVVMPKLVI
TSDKAVEGEFTNPYAMAKARAAFEIASAVAMVNVKGCFMTKEWEKYIPIVSSAHEMMRVA
AALCDEARELEKSVDGVIRKPHKKDGVIVAKTKLISKPE
>A0A1V5A0P2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoregulaceae archaeon PtaU1.Bin222|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVSNMKAWKP
DFCIVVSPNGVLPGPTGAREELAKSGIPCIVITDDVTTKKEWEGIKTSQFGYIIMKADSM
IGARREFLDPIEMADFNGNLVKVLAGTGAFRKLQVAIDQVIDQVKAGKKGAELVLPKIVM
TTDKAVDGEFTNNYALAKARAAHEIAMAVAGQNVKGCFMTKEWEKYIPIVASAHEMMKVA
AALCDEAREIEKAGDTVLRQAHKKDGVLVKKNKLVAKFD
>A0A8J7RXY8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanofollis sp. W23|TrEMBL
MAELLLDERADREDMQTFMATSGTKLQPEDIDRVVTTMKEWVPDFCIVVSPNGILPGPTG
AREQLAEAGIPCIVITDDITGKKDQFAALKESQFGYIIMKADSMIGARREFLDPVEMADF
NGNLVKVLALTGAFRKLQLELDKVIDQVKEGKKGADLVLPKLVMNSDKAVAGEFSNPYAL
AKARAAYEIAQAVAGVNVKGCFMTKGFENYVPIVASAHEMMREAAYLCDEAREIEKAGDG
IIRKPHKKDGVIVSKTALISKPE
>A0A1D3KYY6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium congolense|TrEMBL
MVVKIGVIKCGNIGTSPVIDLVLDERADRPNIDVRTVGSGAKMNPEQIEDAVPKIADFDP
EFVVFISPNPGAPGPAKARELLSAMDIPAIIVGDAPGIRAKDEMDEQGLGYILVKADPMI
GARRELLDPTEMASFNSDVLKVLAATGAYRVVQSTLDAVIAAAEAGNDIELPKVVISAEK
AVDAAGFANPYAKAKALAAYTIAEKVADVDVKGCFMTKEAEKYIPIVASAHEMLSAAAKL
AVEAREIEKANDTVLRTPHGAQGQTVSKTALMDKPQ
>A0A1D2X0W5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosphaera sp. WGK6|TrEMBL
MVVKIGIIKTGTIGTSSLIELILDERADREDIDVRIVSSGAKMSKQQIEEVTFKINDFNP
DIIIFISPNPNAKQPKNARKILTELEIPTIIIGDKPGEVAIPEIKEQKFGYIIIQADPMI
GARREFLDPTEMVLFNADVLKVLAVTGVFRLIHKTLDNVIDDIKNNEPIHLPELLVTEKE
AVDTAGFKNPYAKSKAIAAYNITKQVAQMNINACFKVKESDEYIPIVAAAHEMMSSAAKL
ADEARMIEKTNDSVLRTPHRRDGSTLSKTSLMDNFR
>A0A0F8PCM9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp. 1.H.A.2.2|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVCGTGAKMGPADAADTESFKQWNADF
VVIISPNAAAPGPTAARELWKDVPCIVVSDGPTKKEAREAFEQDGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLIQEELDRVTEQVASGKSGKELELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
ATQAREIEKSNDTVFRQPHAKSGALLKKVKLYEKPQ
>A0A662VUF0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobales archaeon|TrEMBL
MVKVGVLKMGAIGTALLVEYLLDERADREDIEVRVVTSGAKMSPDEAVVAEKLKEFDPDV
VIVVSPNAALPGPKAAREAFEGKPVIIISDAPAKKAKDEFVEKGFGYILINADSMIGARR
EFLDPTEMALFNADVVKVLAATGAFRLVQEAIDKVIDDIKAGKEPELPRVIVTAERAVEA
AKFTNPYAKAKAMAAYYIAEKVADIDVKGCFIEQDPNKYIPLVAAAHEMMRVAAIEADRA
REIEKGGDNVYRNPHAKDGKILSKTKLMEKPE
>A0A662IRJ4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thermoprotei archaeon|TrEMBL
MSQQAPVRIGIVKLGCIGCAPLLEYLLDERADRGDITVRVVTSGAKMTPEEAENVIKMLE
PFKPQLIIIASPNAALPGPTKAREAAKALNAPIVIITDAPAKKAASKFEEGGFGYIIVEA
DSMIGARREFLDPTEMALFNADIIKVLAITGVFNLIVKTIDEMISSIKRGEEVKLPKIIV
NKDLALENAGFSNPYAQAKAMAAFEAARRVADLTTEGCFKVQEWEKYIPLVAAGHELMRY
AAKLADEAREIEKGIDQVMRMPHRASGELAVKRKLIEKLPSKRE
>A0A5E4HUR3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon|TrEMBL
MVVKVGFIKLGNLGTSQVIDLLLDEIAAREGIAVRVFGTGAKMGKDEAAETASFKNWGPN
FVVMISPNSSAPGPTAARDVWKDTPTIVVSDGPTKKEDREKLEQAGFGYMILPVDPLIGA
KREFLDCVEMATFNTDALKVLTICGAIRLVQTEIDKVIDQVAAGTKPLVLPKILAKPEKC
VESAGFNNPYAKAKALAALHIATKVAEIDFPACFVLKEVDQIATAAAAGHEAMRAAARLA
DEAREMEKANDSVLRKPHAKDGRLLTKTKLLEKPQ
>A0A842TC60|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MSENVLNIGVLKNGTIGSSVLLSFLIDERAEGERVIFREVTSGPKMHPPEECVETMKKLL
EFQPDLILMSSPNAALKGPKAARELVGDIPSIVISDAPAKKAIEEFKEKGLGYIIVECDS
MIGARRPFLDPIEMSVFNSNLLKVLAVTGVFNIIVDELNAVIMDMLEGKTPTLPQIEVDA
TTAVKAARFANPYAEAKAIAAFEIASKVSKITGKACFVLKEREDYMPLLAAAHEMMKTAA
DMCQVAREIEKSNDTVIRRPHRSSQELLEKRALHEKEK
>A0A524DY18|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MLKIGILKNGTIGSSLLLAFLIDERAESTRINVYEVTSGAKMHPPNMCTETMEDLLKWKP
ELIIMSSPNAALKGPVAAREMAKQAGIPSIVISDAPAKKAVEEIKEKGMGYILVNCDSMI
GARRPFLDPIEMSIFNSDLLKVLAITGALQVIAQELNKVIMDMLDGRTPTLPQIIVDAST
AVKAARFSNPYAEAKAIAAFELAASVSAITARACFVMKEREEYMPFLAAAHEMMRTAALM
CDKAREIEKSNDTVIRRPHHAKQHMLTKIALMEKEK
>A0A7K4GLE0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MSEEKFLKIGILKNGTIGSSLLLAFLLDERAEATRIKVREVTSGAKMNPPEECIDTMRKL
LEFEPQLILMSSPNAALKGPKAARELAGNIPTIVISDAPAKKAIEEFKEKNMGYIIVGCD
SMIGARRPFLDAIEMSSFNSDLLKVLAITGAFNIITNELNKVILDILEGKAPILPQIEIN
ATNATETAGFSNPYAQAKAIAAFELAASVSKITGRACFVLKDRPDYMPLLAAAHEMMRTA
AELCTQAREIEKSNDTVLRTPHHVKQHLLTKRKLHEKEV
>A0A7K4CGZ3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothrix sp|TrEMBL
MFKIGFVKLGNIATSTAIDLALDEIAERTDLEFKIISFGPKMTKKEGEASAELKAWGPQL
VVISSPNAATAGPTSAREQFKGLPTIVISDGPTKKEARDALAAEGFGYIILPVDPLIGAK
REFLDPSEMALFNSDALKVLAACGAIRLVQEELDKVMTSIASGEPKLPAILATPEKCAER
MNFSNPYARAKAVAALYMAQTVATIDATACFRLKELEAIALMAAAGHEVMRAAGRLADES
REMEKANDSVSRKPHARTGELMAKTRLLEKPGKI
>H8I793|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocella conradii (strain DSM 24694 / JCM 17849 / CGMCC 1.5162 / HZ254)|TrEMBL
MTVRVGVVKLGNLGTSRYIDLILDERADRDIYTRVVGTGTKLGEPDAEEAATKILDFKPQ
LAIVISPNGALPGPTKAREMIKAAGVPTIMISDAPAAKVKDDLKAKGFGFFIIKCDSMIG
ARRQFLDPTEMVLFNADLQKVLADTGVVRLLQKELDRVVAEIASGATPNLPQIVVDSNKA
LAESGYKNPYARAKAFAAFAAAEKVGDIDVLGCFVQKEMEQYVITVASAHELLRAAAMLC
DEAREIEKSGDSVYRTPHANDGKILSKSTLVSKPE
>A0A0F8EYV1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp. 2.H.T.1A.6|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVCGTGAKMGPADAADTESFKQWNADF
VVIISPNAAAPGPTAARELWKDVPCIVVSDGPTKKEAREAFEQDGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLIQEELDRVTEQVASGKSGKELELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
ATQAREIEKSNDTVFRQPHAKSGALLKKVKLYEKPQ
>A0A0E3R7X8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina barkeri 227|TrEMBL
MVNIGFIKMGNLGMSQVINLVQDEIAAREGITVRVFGTGAKMSPAEAAASESFKQWDADF
VIIISPNAAAPGPKAAREVWKDVPCIVVSDGPTKKEAREALEKAGFGYMILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLVQEELDKVTDQVASGKSGKELELPHIFAKPEK
CVEYAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAASQL
AIQAREIEKSNDTVFRQPHAKNGTLLKKVKLYQKPE
>A0A0F8G1P3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp. 2.H.T.1A.15|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVCGTGAKMGPADAADTESFKQWNADF
VVIISPNAAAPGPTAARELWKDVPCIVVSDGPTKKEAREAFEQDGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLIQEELDRVTEQVASGKSGKELELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
ATQAREIEKSNDTVFRQ
>A0A843ANK6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter arboriphilus|TrEMBL
MVVKIGIIKSGNIGTSPVLDLLLDERADRPNIDVRIIGSGAKMNPEQVEEVTPKVKDFDP
DFAIFISPNPGAPGPAKARELLSGYDIPAVIIGDAPGAGKKDEMDEQGLGYIIVKGDPMI
GARRELLDPTEMASFNADVIKVLALTGAYRVVQNAIDALIEAAEAGKELELPKIILTAEK
AVEAAGFTNPYAKAKAIAAYEAAGKVADIDTKGCFMVRDANQYIPLVAAAHELIGTAAKL
ATEAREIEKANDSVLRTPHAGDGSIVSKTKLLDKPS
>A0A7C5Y1M5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVKVCILKLGCIGASPLLEYVLDERADRGDIEVRVLSVGAKMTEAHAEELVKKALAEDYD
LYIIPSPNASLPGPTKVRNALGEKGKNVIVISDAPARRITKELEEKGFGYIIILADSMIG
ARRGFLDPVEMTLFNADVIKVLAATGVVRLLQVELDKVINSLKAGEKPSLPKIVVDKEVA
TKYAEYRNPYAKAKAMAAYEIAVKVADLTSEGCFKIKERDRYIPILAAAHEIMRYAAELA
DEAREIEKYGDTLVRTPHSSDGTILFKEKLMEEARGR
>A0A126R1S5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter olleyae|TrEMBL
MVVKIGIIKSGNIGTSPVLDLLLDERADRPNIDVRVFGSGAKMNPEQVEDVVPKVDQFDP
DFCIFISPNPGAPGPDKARELLSEKDCPAIIIGDAPGKGKKDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNADILKVLAETGALRLIQKTIDGIIEAADEGKEIELPKLIITAEK
AVDAAEFQNPYAKAKAIAAYEMAGAVANLDMKGCFMTKGYENFIPLVAAAHEMAAYAAKL
AQEAREIEKSNDTVLRTPHMKEGNIGCKFDLISKPE
>A0A7J2MGV4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
AAAGHEMMGAAAVLAREAREIEKSNDTLFRQPHAKAGNLLTKTKLYDKPA
>A0A1V4Z7Z2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocella sp. PtaU1.Bin125|TrEMBL
MTVRVGIVKLGNLGTSRYIDLILDERADRDVFVRVVGTGAKLGEPEAVEAATKIQEFKPQ
VCIVISPNATIPGPTKARDMLKEAGIPTIVISDVPVMKIKDDLKAKGFGFFVVKADSMIG
ARRQFLDPTEMVLFNAEMTKVLTETGVVRLIQKELDRVIGEIAAGQAPVLPQIVVSADKA
VPEAGYKNPYAKAKAFAAYAMAEKVGDLDLLGCFMQKEMEQYIITVCSAHELLRAAARLV
DEAREMDKSMDAVLRTPHAADGKILSKTTLVSKPE
>A0A063Z759|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoculleus sp. MH98A|TrEMBL
MVVKVGIAKLGNIASGVMGELLLDERADREDMITFMATSGTKLQPEDIERVVSNMKAWGP
DFCIVVSPNGVLPGPTQAREDLAAAGIPCIVITDDVTTKKEQFEALKASNFGYIIMKADA
MIGARREFLDPIEMADYNGNLVKVLALTGAFRKMQMELDKVIDQVKAGKKGADLALPKVV
MTSDKAVDGEFSNPYALAKARAAYEIAQSVAGVNVKGCFMTKEWEKYIPIVSSAHEMMRQ
AMLLCEEARALEKGVDGVIRKPHKKTGEIVSKTALISKPE
>A0A101H0F1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocalculus sp. 52_23|TrEMBL
MFICLFIKKGSVLKFFERCNSMVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATS
GTKLQPEDIDRVITNMKAWGPDFCVVVSPNGVLPGPTGAREELAKAGIPVVVITDDITTK
KEQFDTLKASSFGYIIMKADAMIGARREFLDPVEMADYNSNLVKVLALTGAFTKLQVELD
KVIDQVKAGKKGADLVLPKVVMTSDKAVDGAFNNPYAMAKARAAYEIAQSVAGVNVKGCF
MTKEWEKYIPIVCSAHEMMRQAAALCDEARELEKGADCIIRSPHKKDGVIVTKTKLISKP
E
>A0A842LT98|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermobacter sp|TrEMBL
MVVKIGIIRCGNIGTSPVLDLLLDERADRPNIDVCVVGSGAKMNPDEIERAVPTMLEMDR
DFVIFISPNPGAPGPAKARELLSEADVPAMIIGDAPGLRVKDEIEEQGLGYIIVKADPMI
GARREFLDPTEMASFNSDVIKVLAFTGAYRVVQNTIDAMIADVEAGKAPELPQVVIDTDV
AVEAAGYENPYAKAKAMAAYEIATKVADIDVKGCFMVQDPDKYIPIVASAHEMLAAAAKL
AVEAREIEKANDTVLRTPHGKEGETLSKTDLLAKPE
>A0A848DBS0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Ethanoperedens thermophilum|TrEMBL
AQGPVEARKIWKDIPTIIVSDGPTEKDDRQKLADAGFGYIILPVDPLIGAKREYLDTVEM
VNFNAEVNKTLAFTGAMRLVQETIDGVIEEIKTGETLNLPHILAKPEKCIEYGGFSNPYA
KAKALAALHILSKAAEINSKACFGMKGTEAITLTTAAGHEMVRTASVLADEAREIEKCND
AVSRKPHARDGRILSKTRLYEKPE
>A0A1V4Y6W8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomethylovorans sp. PtaU1.Bin073|TrEMBL
MAKIGIIKLGNLGMSQVIDLVQDEIAAREGISVRVFGTGPKMGKDEAAATAEFKDTGADF
YIMISPNSSAPGPTAAREHFKDVPCIIVSDGPTKKEDREALQQAGFGYIIMTVDPLIGAK
TEFLDPVEMASFNSDAMKVLSTCGVVRLIQEELDKVAAQVDAGEPIQLPHILAKPEVCIE
RAHFSNPYAKAKGLAALHMADMVAKINFPACFMMKELEQVALTTAAGHEMMRAAAQLAIE
AREIEKANDTVFRQPHSKKGGKLFQKTKLYEKPQ
>A0A1V4V1E9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosaeta sp. PtaB.Bin087|TrEMBL
MFKIGFIKLGNVASSLVADLALDEIAERTDVEVRSLSFGAKMTVKEAEMSAELKGWRPQL
VVIVGPNASTPGPTAARALYREVPTIVISDGPTKKEAREALEAEGFGYIILPFDPLIGAK
REFLDPAEMALFNSDALKVLSICGSVRLVQEELDRSMASIVSGSPTLPHILASPEKCTER
MDFENPYARAKAIGALHMAQTVAAIDAAACFRLKEMDRIALTAAAGHEVMRAAARLADEA
RELEKSTDSVSRRPHARSGAILAKTGLLDKPEPV
>A0A843LBD3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoculleus sp|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDIITFMATSGTKLQPEDIDRVVTNMKAWGP
DFCIVVSPNGVLPGPTKAREDLAAAGIPCIVITDDVTTKKEQFEALKASNFGYIIMKADA
MIGARREFLDPIEMADYNGNLIKVLAITGAFRKMQMELDKVIDQVKAGKKGADLVLPKVV
MTSDKAVEGEFSNPYALAKARAAYEIAQEVAGVNVKGCFMTKEWEKYIPIVASAHEMMRQ
AMLLCDEARNLEKAVDGVIRKPHKKTGEIVSKTALISKPE
>A0A1G8ZK29|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoculleus thermophilus|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMITFMATSGTKLQPEDIDRVVSNMKAWGP
DFCIVVSPNGILPGPTQAREALAAAGIPCIVITDDVTSKKEQFEALKASNFGYIIMKADS
MIGARREFLDPIEMADYNGNLIKVLSVTGAFRKLQMELDKVIDQVKAGKKGADLVLPKVV
MTSDKAVEGEFTNPYALAKARAAYEIAQSVAGVNVKGCFMTKEWEKYIPIVSSAHEMMRQ
AMLLCEEARELEKGMDGVIRKPHKKTGEIVSKTALISKPE
>A0A2Z4L954|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosphaera sp. BMS|TrEMBL
MIKVGVVKVGNIGISTIIDLILDERADRDDFHIRTISTGSKMGQNEVNDIIRRVKNIDVD
LLVFISPNPGARQIKHAIEEITKLNLPLVIIGDKPGERAIPFMKEHHLGYILIRADAMIG
ARREFLDSTEMALFNSYVLNVLSITGVIRLIHEEIDKVLYSVKDDAPIEFPEIIVTAQKA
VSYARFNNPYAEAKAMAAYQIATQVSEMDVTACFRVNDPEEYIPLVVAAHEMMKAASILA
EEARELEKSNDTVTRTPHKRDGSIVFKSKLLHNYETEETFDYHED
>A0A166CUS3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter filiformis|TrEMBL
MVVKIGIIKSGNIGTSPVLDLLLDERADRPNIDVRVIGSGAKMNPEQVEEVVPKVKEFNP
DFAIFISPNPGAPGPAKARELLSGYDIPAVIIGDAPGASKKDEMNEQGLGYIIVKGDPMI
GARRELLDPTEMASFNADVIKVLSLTGAYRLVQTAIDGLIADVEAGKDLELPKIILTAEK
AAEAAGFANPYAKAKAIAAYEAASTVANIDTKGCFMVRDAEQYIPLVAAAHELIGVAAKL
ATEARDIEKSNDTVLRTPHNKDGAIVTKTALLDKPA
>A0A498GYG8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoculleus taiwanensis|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMITFMATSGTKLQPEDIDRVVNNMKAWGP
DFCIVVSPNGILPGPTGAREALAAAGIPCVVITDDITTKKEQFEALKASNFGYIIMKADA
MIGARREFLDPIEMADYNGNLVKVLSVTGAFRKMQFELDKVIDQVKAGKKGADLALPKVV
MTSDKAVDGEFSNPYALAKARAAYEIAQSVAGVNVKGCFMTKEWEKYIPIVSSAHEMMRQ
AMLLCEEAREIEKSTDAVIRKPHKKTGEIVAKTALISKPE
>F6D7B4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium paludis (strain DSM 25820 / JCM 18151 / SWAN1)|TrEMBL
MVVKIGVIKCGNLGTSPVIDLMLDERADRPNISVKSFGSGAKMGPEEIEEVVPKVADLDA
AFVIFISPNPAAPGPAKARELLSAMDVPAIIVGDGPGARVKDEMNEQGLGYILVKGDPMI
GARREFLDPTEMASFNADVIKVLAATGAYRCVQKTLDALIAAAEAGEAIEVPKLVLTRDK
AIAAAEFKNPYAKAKAMAAYTIAEKVADIDVEGCFMTKDAEKYIPIVASSHEMIAVAAKL
AAEAREIEKANDTVLRTPHSGKGQLVSKTTLMSKPE
>A0A3R7AKZ3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MSETVKVGIVKAGCIGVLPLIEILLDERADRTDIDVRVVGSGAKLGLEQCQEVTDIMIKQ
KPDLAIFVGPAQAAPGPTEARRMLAEAGIPTVVISDSPAKKLTKEMEDAGLGYIIVEADS
MIGARREFLDPTEMALYNSDVIRVLAATGVLSLIVREIDKVIDSLKKGEEPVLPRLIIDK
ELVASNFKNPYAGAKAVAAYEIARNVARLNTEACFKVKEWTVYTQLAASGHEMMRAAAQL
ADEARELEKSCDSVLREPHFKDGTLGEKRSLIEKPKKKAPSP
>A0A523T9T1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MEESLGKVKIGVFKCGNVGTAPIFELLLDELAQRKDITVRTITTGSKMSLEDVKDAFPKI
FEFAPDLLVLISPNPTVSGPAAARAMAIQNGINTVVLSDAVAKRMITDLEKQGVGYIIVL
GDPLIGARREFLDPVEMALFNSNIMKVLAVTGVFRLIHQEIDRVIAVLKEKLAVRLPRLL
IDTETIRDNSDFMNPYAKAKAMAAYHIASKIPEINTKACFMEKDDEKYIPLVACAHEMAQ
AAAKLAEEAREIEKYSDTVVRKPHSKRGEPLTKTKLMQSPKFDDDLYRKWLKTLPTN
>A0A419KFK2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MGCLGSVPLLEFLFDERAERTDLDVRVVGSGAKLGPEQCVEVTKTLLNLKPDFIIVAGPA
QQTTGPKEARKLLADSGIPTLIISDGPMVRIKGELEKAGFGYIIVEADPMIGARREFLDP
VEMAIFNSDVIKLLACTGVFNVIVDAVDRIIESLKRGEKPSLPHIVVDRNLALKAAEYSN
PYARAKALAAFDLAKQVTSLHVEACFKLTDWKEYTLLVAAGHEGVRLASKLSEEAREIEK
ASDSVLRRPHHRDGVRSRKRALIEKPKKD
>A0A497M8M7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVVKLGFIKLGNIGVAPLLELALDERAEREDIDVRVFGSGAKLTPEQAEDLAERLIAYKP
DLAVSVSPNAALPGPKRIREKLKEAGIPLITVTDAPGKKAVKDIEEKGFGYIIVEGDAMI
GARREFLDPVEMLIFNADIIKVLSVTGVFNVFQEAFAQVIEAVKKGEKPELPRIVVNAET
AVKAAGFSNPYAQVKAMAAYEILRKVAEMNMEGCFKIQERERYVPMVAAAHEALRAAVTL
ANEAREIEKSLDTVLRKPHDKEGRILVKRKLLEKPSASG
>A0A497MW17|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVVKIGFVKLGNIGVAPLLELALDERAEREDIDVRVFGSGAKLTPEQAEDLAEKLVAYKP
DLAVIVSPNAALPGPKKVREKLHEAGIPAISVTDAPGKKAVKDIEEKGFGYIIVEGDAMI
GARKEFLDPVEMLLFNAEIIKVLAITGVFNVLQDAFAQLIESLKQGAKPELPRIVVNSEV
AVKAAGFQNPYAQVKAKAAYEILKKVAEMNVEGCFKVQERERYVPIVAAAHEALRAASLL
ADEAREIEKTLDTVLRKPHDKDGKVLVKRKLFEKPSAQ
>A0A3R7BT07|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MPLLEVMLDERAERSDIDMRVIGSGAKLGPEQCREVSELMIKLNPDLVILIGPAQTTPGP
SEARKMLREAGLPTIVISDFPAKKLVDEMEKSGLGYIIVEADSMIGARREFLREKVRIKN
LKLGCLLTARRSIEDAIARVKDAWDFFFMRLEEKSLPALEQIAKECKRLDKPIYAYFVVG
TPRNAEIIKMIGWPVTTTMEKVEEFAAKLEGTLDGIIATCVGDYEGDKELLEKLQKFREK
>A0A7C7UD76|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVVKLGFLKLGNVGVAPLLELALDERAEREDLDVRAFGSGAKLNPEQASDIAEMLVAYKP
DLAVVISPNAALPGPRKARERLAEAGIPTVVVSDAPAKRAVKEMEEKGFGYILVEGDAMI
GARKEFLDPVEMLIFNADIIKALAVTGVFNVFQEAFASMVEALKRGEKPQLPRIIVNKEA
AVEAAGFFNPYAKAKAMAAYEMLRKVAELDVEGCFKVQERERYVPIVAAAHELVRAAMRL
ADEAREVEKNLDEVQRKPHDKRGKILSKRKLMEKPSAP
>A0A7J2KTN3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Euryarchaeota archaeon|TrEMBL
MMVKLLVIKIGNIATSLVLELLLDERADRKDIEVDVATTGAKMTPGDAERVLARVNLDEY
NLIIYISPNPAIAGPEMIINALKGRNAIIIGDAPGVKIIKKLEEAQLGYLFILGDSMIGA
RREFLDATEMAIFNAEMLKVLSITGALRLVQEEIDKAVDALKKDEKYLPKLVVDTAEAVE
AAGFENPYAKAKAMAAYEAIKLIGKLNVKGCFMVKDAREYIPMVTSAHELLRMAGIYSDE
AREMEKTMDTLLRKPHSRSGELLKKRSLMEKPS
>A0A8J7W7W3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocalculus chunghsingensis|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMESFMATSGTKMQTEDIERVVSNMKAWGP
DFCIVVSPNGILPGPTSAREDLAKAGIPVVVITDDITSKKDKFDELKASNFGYIIMKADS
MIGARREFLDPVEMADFNGNLIKVLALTGAFTKLQVALDEVIDQVKAGKKGADLVLPKIV
MTADKAVDGEFVNPYSLAKARAAYEIAQGVAAVTVKGCFMTKEWEKYIPIITSAHEMMRH
AALLCEEARELEKAGDSVLRKPHKKDGVLVSKTKLISKPE
>A0A7K4AGJ4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothrix soehngenii|TrEMBL
REALSAEGYGYIILPMDPLIGAKREFLDPAEMALFNSDALRVLAACGAIRLVEEELDRSI
ASIISGQAKLPTILATPEKCAERMHFSNPYAQAKAMGALYMAQTVASIDAAACFRLKELK
PIALTAAAGHEVMRAAARLADEARELEKSNDTVSRQPHARTGELMQKLSLLDKPEKI
>A0A1Y3GBB2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanonatronarchaeum thermophilum|TrEMBL
MLVGIGKFGFIGSSFVDALFDERADREDVDVRVVGSGSKMGVDDCMSVMKCLLEFDLDCL
ILVSPNPSMPGPAKARELAVESGLPCIVVSDYFGVGSKGDVEDSGLGYIYVKGDPLIGAR
REFLDFVEMADFNSNVLKVLSLCGSFRKLQLEIDRFVGSDLDDPYLPRCVITPEKAVEDE
FSNPYAESKAIAALEIANRVAEINHKVCFKINDRERYVRLASSSHEMLKKAAVLAEEARE
IEKKNDSVRRTPHKKDGGCLEKKRLHEDI
>A0A662H1R1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thermoprotei archaeon|TrEMBL
MRKVRIGVLKIGCTGCTPLLEYLFDERAERVDIEIRVFGCGAKMLEDEVKEVCELVIKSN
PDLVIVVTPNASLPVPLKALNTISSTGAPTLVISDAPAKKAVNKFEAMNIGYLLVLADSM
IGARREFLDPVEMAIYNSDIIKVLAITGAYNIIYEQVSKLVDALKKGEKPVLPQIIVDSE
TAVNAAEFNNPYARAKAIAAYEIAKTVSKLTTVACFKIKERERYISYAAAAHEMMRYAAH
LAEEAREIEKYGDHVVRKPHSKEGEVLRKLKLLEKTKGGQLNEPLKT
>A0A2H4VI87|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium sp. MZ-A1|TrEMBL
MVVKIGVIKCGNIGTSPVLDLVLDERADRPNIDVRGVSSGAKMNPEQIEEVVPKIMDFDP
DFVIFISPNPGAPGPAKARELLSGMDVPALIIGDAPGMGKREEMDEQELGYIVVLGDPMI
GARREFLDPTEMASFNADVIKVLAATGAYRVVQETIDGMIAAAEAGEAIELPKVVIDAAK
ATETAGFASPYAKAKAMAAYEMAAKVGDIDLKGCFMVKEMEKYVPIVASAHELIATAAKL
ATEAREIEKANDTVLRKPHGPQGQTLSKTVLVSKPE
>A0A101DQ41|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacteriaceae archaeon 41_258|TrEMBL
MVAKIGVLKCGNLGTSPVIDLVLDERADRPNVEIRVMGSGTKMNPDDIEFVVPKMLELDR
DFVIFISPNPGAPGPARARELLSEADVPAMIVGDAPGLRVKDEIEEQGLGYIIVKADSMI
GARREFLDPTEMAAFNADLMKVLALTGAYRVVHNTIDAMIADVEAGKEIELPQLVITRDV
AVEAADFQNPYAKAKAMAAYEIASKVADIDVEGCFMVQDPEKYIPIVASAHEMMSTAARL
AEEAREIEKSNDTVRRTPHGKEGETLSKRKLLEKPS
>A0A7C3A5B6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobia archaeon|TrEMBL
MSRIVDLILDERADREDVDVCVVGSGAKMTEAHAETAAKALLQFDPDFAIVISPNAALPG
PKKARNVIKDGGKPCIVVSDAPGKKAVEELKSEGFGYIIITGDPMIGARRQFLDPVEMSL
FNADVLKVLSICGVVRIMQEELDTVIEQIKKGETPTLPQIVINAETAVNRAGFSNPYAAA
KAFAAYSIAEKVADITVQACFVVKEAERYVPMCAAAHEVMRYAALLADEAYEIEKYGDNL
LRTPHAKTGEILKKRKLLEKPA
>A0A7C1E9C6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobia archaeon|TrEMBL
MDVVKIGFAKLGNIGISRIADLLLDERADREDIDVRVLGTGAKMTPEAAPDVARLLDWGP
DLVLVLSPNAALPGPKKAREMAKEKGIPCIVVSDAPALKAKDKLKEDGFGFIIIPGDPMI
GARREFLDPVEMSIFNVDVMSVLSATGVVKLVADEIDRVITEIRAGGAVNLPQIVATAEK
AVEAAGFTNPYAKAKAIAAYSMAEKVAELDVKGCFMMKEPEKYVPIVAAAHELLAEAAKL
AKEAREIEKYTDSLLRMPHARTGELLKKRKLMEKPSA
>A0A524E8K9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thorarchaeota archaeon (strain OWC)|TrEMBL
MMQKKRVAVLKLGCIGSLPFLDLILDERAEREEIEIACFGTGSKLDASLCEDMARKAQET
KADLYLIATPNAKLPGPSTARKLLGESALPSITITDNPGRKAFLGKSGETHSDLSDNVGF
IIVPMDPMIGARRDFLDATEMVIFNGHLLNTLASTGVIRATHALIDNALESLEHENLRLP
RIVLSKESALEHAGFSNAYASAKAYAALEILESVAPLTTYACFREKERDKYLLMTAAAHE
MVRAASKLADEAREIEKSNDTILRTPHRKEKGMRTKTKLLSKSE
>A0A5K7X943|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Lacipirellula parvula|TrEMBL
MWNGGGDAAPHSTFDIPHLKSLRRVVDPRLPVTSYQSLTSMSLKKILVCLDADPQPSVFD
GVVAVDSGVDFLFRHGGVAAAQVRDLVYGAMFTRGPQELKNTAVFIGGSDVTVAEGLLKA
ATEAFFGPMRVSVMLDANGANTTAAAAVLAARRHVPLSGAIVTVLAGTGAVGRRVVRLLA
SEGARVRVASRKLTHAEGTCDKISRIVPGADLTAWTNENAMAAATAVEGAQAVIACGPPG
VELLPKGYLAQAAGLQAAIDLNAVPAHGLGDVAPTDKATHHGAIVCYGALGVGGTKMKIH
KAAIAKLFTRNDLVLDADEIYAIGKEL
>A0A523XLA0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Heimdallarchaeota archaeon|TrEMBL
MVKITFVKIGNITLTTLIDIMLDERASRTDIEATVISSSTKMKPDAVERIFPLIDQVETD
LMVMISPNANDKGPQSVIDRYKDKYPLIVVSDGGDKEVRAKWKEDGVGYIIVPFDPMIGA
KRDFLDATEMCLFNGYIITTFSTCGVFAYINELMDGVIEQLKAGEKPKLPTRNMSAIGV
>A0A843CT26|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobium sp|TrEMBL
VEGEFTNPYAYAKARAAYEIAQAVAGVNVKGCFMTKGHENYTPIVASAHEMMRAAMVLCD
EARELEKGCDGVIRKPHKADGVIVEKKQLISKPW
>A0A1V5AZK7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosaeta sp. PtaU1.Bin055|TrEMBL
MFKIGFIKLGNVASSLVADLALDEIAERTDVEVRSLSFGAKMTVKEAEMSAELKGWRPQL
VVIVGPNASTPGPTAARALYRDVPTIVISDGPSKKEAREALEAEGFGYIILPFDPLIGAK
REFLDPAEMALFNSDALKVLSICGSVRLVQEELDRSMASIVSGSPTLPHILASPEKCTER
MDFENPYARAKAIGALHMAQTVAAIDAAACFRLKEMDRIALTAAAGHEVMRAAARLADEA
RELEKSTDSVSRRPHARSGAILAKTGLLDKPEPV
>A0A660HS86|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina flavescens|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGIIVRVFGTGAKMSPAEAADSESFKQWNADF
VVIISPNAAAPGPTAAREIWKDVPCIVVSDGPTKKEAREALEQEGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSICGVVRLIQEELDKVTDQVASGRSGKELELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIEQVCLTAAAGHEIMEAAAQL
ATQAREIEKSNDTVFRQPHAKNGTLLKKVKLYEKPQ
>A0A0H1R234|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoculleus sediminis|TrEMBL
MVVKVGIAKLGNIASGVMGELLLDERADREDMITFMATSGTKLQPEDIDRVVSNMKAWGP
DFCIVVSPNGVLPGPTQAREDLAAAGIPCIVITDDVTTKKEQFEALKASNFGYIIMKADA
MIGARREFLDPIEMADYNGNLVKVLAITGAFRKMQMELDKVIDQVKAGKKGADLALPKVV
MTSDKAVDGEFSNPYALAKARAAYEIAQSVAGVNVKGCFMTKEWEKYIPIVSSAHEMMRQ
AMILCEEARDLEKGMDAVIRKPHKKTGEIVSKTALISKPE
>A0A7J3S8B4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacteriaceae archaeon|TrEMBL
MVAKIGVLKCGNLGTSPVIDLVLDERADRPNVEIRVMGSGTKMNPDDIEFVVPKMLELDR
DFVIFISPNPGAPGPARARELLSEADVPAMIVGDSPGLRVKDEIEEQGLGYIIVKADSMI
GARREFLDPTEMAAFNSDLMKVLALTGVYRVVHDTIDAMIADVEAGKEPTLPQLVVTRDV
AVEAAGFQNPYAKAKAMAAYEIATKVADIDVEGCFMVQDPEKYIPIVASAHEMMSTAARL
AEEAREIEKSNDTVKRTPHGKEGETLSKAKLLEKPS
>R9SJF9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter sp. AbM4|TrEMBL
MVVKIGIVKSGNIGASPVLELLLDERADRPNIDVRVFTSGAKMNPEQVEDVVPKVKDFNP
DFVMFSSPNPTAPGPAKARELLSEMDVPAFIIGDAPGKRAKDEMDEQGIGYIIVEADSMI
GARREWLDPTEMSVFNSDLIKVLACTGAYRLIQNTIDGVIAQADAGEEIELPKLVINAQK
AVDAAGFTSPYAKAKAYAAYEMCAKVADLDMKGCFMMKNYEEFLPVVAAAHEMASAAAQL
ATEAREIEKANDTVLRTPHMSDGSTGKKVNLISKPE
>A0A843J650|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter sp|TrEMBL
MVVKIAILRSGNIGTSPILDLLLDERADRPNIDVRVFGSGAKMNPEQVEDVVPKFKQFDP
DFCIFISPNPAAPGPARARELLSEIDKPAIIIGDAPGKGKKDEMDEQGLGYIIVMADPMI
GAKREWLDPTEMAIFNADIIKVLAETGALRLVQKTIDGVIEAIEAGNEVELPKLIVTAEK
AVEAAKFQNPYAKAKAIAAYEMAGAVAGLDMKGCFMTKGFENFIPLVAAAHEMAACAAAL
AAEAREIEKSNDTVLRTPHMKEGNVGCKLDLISKPE
>A0A6B9TIK5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermobacter sp. THM-2|TrEMBL
MVVKIGIIKCGNIGTSPVLDLLLDERADRPNIDVCVVGSGAKMNPDEIERAVPTMLEMER
DFVIFISPNPGAPGPAKARELLSAADVPAMIIGDAPGLRVKDEIEEQGLGYIIVKADPMI
GARREFLDPTEMASFNSDVIKVLAFTGAYRVVQNTIDAMIADVEAGKAPELPQVVIDTDK
AVEAAGYTNPYAKAKAMAAYEIATKVADIDVRGCFMVQDPDQYIPIVASAHEMLSAAARL
AVEAREIEKANDTVLRTPHGKEGETLSKKDLLAKPE
>A0A328SAV9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosphaera sp. SHI613|TrEMBL
MIKVGVVKVGNIGISTIIDLILDERADRDDFHIRTISTGSKMGQNEVNDIIRRVKKIDVD
LLLFISPNPGARQIKHAIEEITKLNLPLIIIGDKPGERAIPFMKEHDLGYVLIRADAMIG
ARREFLDATEMALFNSYVLNVLSITGVVRLLHEEIDKVLYSVKNKTPIVFPEIIVTAQKA
VSYARFSNPYAEAKAIAAYQIAAQVSEMDVTACFRVSDPKEYIPLVVAAHEMMKSASMLA
EDARELEKTNDTVTRTPHKRDGSIAFKSKLLHNYETEDEFEQWYSNRE
>A0A0W8F7P0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|hydrocarbon metagenome|TrEMBL
MFKIGFVKLGNIATSTAIDLSLDEIAERTDIEFKIISFGPKMTEKEGKGAEELKAWQPQL
VVISSPNAATAGPTAAREAYRGIPTIIISDGPSKKEAREALSAEGYGYIILPMDPLIGAK
REFLDPAEMALFNSDALRVLAACGAIRLVEEELDRSIASIISGQAKLPTILATPEKCAER
MHFSNPYAQAKAMGALYMAQTVASIDAAACFRLKELKPIALTAAAGHEVMRAAARLADEA
RELEKSNDTVSRQPHARTGELMQKLSLLDKPEKI
>A0A833DBX7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Nitrososphaerales archaeon|TrEMBL
MPVNITVVKTGFIGVTTLIEVLLDERASRKDISVRSITSGSKMSITDTQEVEKLSSSLDT
DLYIVVSPNASLDAPKNLALNLGKIKPTILISDSPASKIKDELVDKIGYIFVQGDPLIGI
HKEFLDPIEMSNFNSDVLKVLSITGAFQALINEIDKVIEQIKTSQSIVLPKLVIGKHTAV
SNSGLTNPYSKAKALASYEIARLVARLSAEGAYKEKDRERRLLTVSASHELIRQAAKLAD
EAREIEKHSDSVNRYIHATTGKTLTKKKFFDSV
>A0A424Z3U6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosalsum natronophilum|TrEMBL
MAKIGFIKLGNLGISQVIELVQDEIAARENISIRVFGTGPKMGKDEAGDTSQFKDMEWDA
DFYVLISPNASAPGPTAAREIWKDVPCIVISDGPTKKEDRQALEDAGFGYIILKVDPLIG
AKTEFLDSSEMASFNADVMKVLSTCGVVRLIQEELDNVAEQVDSGKSGSELELPHILGKP
EVCVERAEFTNPYAKAKALASLFMAEKVAQINFPACFMMKEIEQVALTTATGHEMIRAAA
DLAIEAREIEKASDSVIRTPHSKKGKVLSKTKLYEKPQ
>A0A550GE62|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MTQNQFKKIGIFKCGNIGTSPLLELLLDELADRKDITVRTVTTGSKMGPQDVEDALPKIF
ELNPDLLIVISPNTALPGPGKVRERISSSGLPGIVISDAPGKRAKEEIEKQGLGYIIITG
DPLIGARKQFLDPIEMAIFNANISKVLAMTGVYRIVHQEIDKVIYAIENEQKPDLPKLIV
DLKTVRDRSEFNNPYAKAKAIAAYGLAEKIAEINVQACFMEKESEKYIPLVTCAHEIAQT
AARLAEEAREIEKCNDTVVRKPHAKDGKLKVKTELMLPPVSEEDFSGEDMP
>A0A7K4I6G3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MSEEQIKKIGVFKCGNIASSPIFELLLDELADRQDIKTRTVTTGSKMSAEDVEEALPKIF
EFDPDLLVLISPNPSIAGPAKVREKFSTSGVPSVVISDAPGKRIRAELEKQGLGYIIITG
DPLIGARREFLDPLEMAIFNSNIIKVLAITGVYRIVHREIDKLAYALRTGLSPVLPKMII
DVNSIRDNSDFKNPYAKAKAMAAYELAEKIAEINLQACFIEKESDKYIPLVACAHEIAQT
AARLAEEAREIEKYNDTLVRKPHAKDGRAKIKTKLMLPPTFDEEFYGKGE
>A0A497LQ84|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKKVKIGIFKCGNIGTAPLLELLFDELADREDISVRSVTTGAKMLAKEVEEALPKIFDFN
PDFLVFISPNPAVQGPTRAREILAEKKIPAIFVSDAPGKRLREEFEKHGFGYIIVMGDPL
IGARKEFLDPTEMAIFNSNIIKVLAITGVYRIIYQEIDKIIHGYKEELTPELPKIVIDTA
SIRDNSDFKNPYAKAKAMAAYELTKKIAEINTRACFMEKEKEKYIPLVACAHEIAQVAAS
LAEEAREIEKYADSLVRRPHSRGGRLKVKEKLMLPPVFDEEIYQKWLKGHKRE
>A0A846PFX8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
QGYFLMLGDPIIGARREFLDPTEMVLFNTDVLKVLAVSGALALVTQAVAKVIEQLKSGSP
IELPRLVINTETAIAHARFMNPYAAAKAAAAYEMIKLTAGINTRACFVAKDMEEYIHLAA
TGHELVRTAAHLAMEARELEKGNDTLLREPHKHGEILTKRKLISKPHSKKEM
>A0A419JHR6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Syntrophoarchaeum sp. WYZ-LMO15|TrEMBL
MVKVGFIKLGNIGMSLIVNLLLDERADREDIDVRVAGTGAKMGKPEAEDVLSFLKWEPDL
LIVTSPNAALPGPKIVREAFEGKPCIVISDGPAKKAVDEMKEKGFGYIILPGDPMIGARR
EFLDPTEMALFNTDVLKVLSVSGAARLVQEEIDRVIGEIKAGGKVTLPQIIATAEVVTQR
AQFSNPYARAKAIAAYSMAEKVAELDAKACFAMKDPEAYTLMVAAAHEIMREAARLADEA
RELEKAQDAVSRAPHGRSGEILSKRGLMEPLK
>A0A5B9M1P4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermobacter sp. KEPCO-1|TrEMBL
MVVKIGIIKCGNIGTSPVLDLLLDERADRPNIDVCVVGSGAKMNPDEIERAVPTMLEMER
DFVIFISPNPGAPGPAKARELLSAADVPAMIIGDAPGLRVKDEIEEQGLGYIIVKADPMI
GARREFLDPTEMASFNSDVIKVLAFTGAYRVVQNTIDAMIADVEAGKAPELPQVVIDTDK
AVEAAGYTNPYAKAKAMAAYEIATKVADIDVRGCFMVQDPDQYIPIVASAHEMLSAAARL
AVEAREIEKANDTVLRTPHGKEGETLSKKDLLAKPE
>A0A7K3YCM0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMITFMATSGTKLQPEDIDRVVNNMKAWAP
DFCIVVSPNGVLPGPTQARENLAAAGIPCVVITDDITTKKEQFAALKESEFGYIIMKADA
MIGARREFLDPIEMADYNGNLVKVLALTGAYRKMQVELDKVVDQVKAGKKGKDLVLPKVV
MTADRAVSGEFSNPYALAKARAAYEIAQQVAAVNVQGCFMTREWEKYIPIVASAHEMMRQ
AMVLCEEARSLEKAMDGVIRMPHKKTGEIVSKKTLISKPE
>A0A068VQ20|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Propionibacterium freudenreichii subsp. freudenreichii|TrEMBL
MDTTENRVPVQIGIFSVSDLTPDPTTGITPTEHERLKNYALIVKKAEEIGLDAFALGEHH
NPPFVSSSPTTTLGWLAAQTSKITLSTATTLITTDDPVKIAEDYAMLQHLADGRVDLMLG
RGNTGPVYPWFGKDIRQGINLALENYNLLHRLWREEVVDWQGKFRTPLQGFTAIPRPLDD
VPPFVWHGSIRSPEIAEQAAYYGDGFFHNNIFWTMNHTKRMVDLYRRRYEHYGHGRYDQA
IVGLGGQFFMRKNSQDAIKEYRPYFDNAPVYGHGPSMEEFTEYTPLTVGSPQQVLERTLS
FKDDVGHYQRQMFLIDHAGLPIKTVLEQLDLLGEILPEMRKGFLEGRPDDIPDAPTHASL
VAARDAAGVAPVEHVKVGADDVTGTSDAPEPPDSVFEK
>A0A832X766|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocalculus sp|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVITNMKAWGP
DFCVVVSPNGVLPGPTGAREELAKAGIPVVVITDDITTKKEQFDTLKASSFGYIIMKADA
MIGARREFLDPVEMADYNSNLVKVLALTGAFTKLQVELDKVIDQVKAGKKGADLVLPKVV
MTSDKAVDGAFNNPYAMAKARAAYEIAQSVAGVNVKGCFMTKEWEKYIPIVCSAHEMMRQ
AAALCDEARELEKGADCIIRSPHKKDGVIVTKTKLISKPE
>A0A833EEN1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermococcus okinawensis|TrEMBL
MVVKVGIIRCGNIGTSPLIDLILDERADRKDIDVRVLGSGAKMGVEQVEEVTKKMIEDIK
PDLIVFISPNPAAPGPKKARELLSKCGIPSVIIGDAPGLKVKDDIEKEGLGYIIVKCDPM
IGARREFLDPVEMVLFNADVLKVLAGTGAIRVVQNAIDSMIDAIKEGKEVELPKIVVNES
RAIESMEYTNPYAKAKVMAAFKIAEMVGDVNVKGCFMVKEREKYIPVVASAHEMIRYAAK
LVDEAREMEKSLDTVSRKPHGSDGRILNKKKLMEKPE
>C9RF17|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocaldococcus vulcanius (strain ATCC 700851 / DSM 12094 / M7)|TrEMBL
MVVKIGIIKCGNIGMSPVVDLALDERADRKDIAVRVLGSGAKMDPESVEEVTKKMVEEVK
PDFIIYIGPNPGAPGPKKAREILSESGIPAVIIGDAPGLRVKDEMEQQGLGYIIIKCDPM
IGARREFLDPVEMALFNSDVLRVLAGTGALRVVQEAIDKMIDAVKEGKEIELPKIVINEQ
KAVEAMEFTNPYAKAKAMAAFVIAEKVGDVDVKGCFMTKEAEKYIPIVASAHEMIRYAAK
LVDEARELEKANDSVSRKPHHPEGKRLNKKALMEKPE
>A0A524DKE2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MSEDKVLKIGILKNGTIGSSLLLAFLMDERAEGKRINVVEVTSGAKMHPPEICLPTIDKL
LEMNPELILMSSPNAA
>A0A523VW30|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MLKIGMLKNGTIGSSLLLAFLIDERAEATRVNVREVTSGAKMHPADHCIETMKKLLEFEP
DLIVMSSPNAALPGPKATRELTGNIPTIVISDAPAKKAIDEIKAKGMGYILVNCDSMIGA
RRPFLDPVEMSIFNSDLLKVLAITGALQIIAEELNKVIMDMLERKSPVLPQIIIDANIAT
EAAKFSNPYARAKAIAAFELAASVSKVTGKACFQLKERSEYMPLLAAAHEMMRTAALLCD
EAREIEKSNDTVIRTPHHAKQQRFLSKIGLYDKEQ
>A0A523B6L8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Nezhaarchaeota archaeon WYZ-LMO7|TrEMBL
MSQQAPVKVGIIKLGCIGCAPLLEYLLDERADRNDISVRVVSSGAKMTPQEAEEVVKMLE
PFKPQLIIIASPNAALPGPTRAREVAKLLNVPTLIISDAPARKAVSKFEEGGFGYIIVEA
DSMIGARREFLDPTEMALFNADIIRVLAITGVFNLIVKTIDDMIASIKKGEEVKLPRLIV
TKEIALENAGFSNPYAYVKAMAAFEAARKVSDLTTEGCFKVQEWEKYIPLVAAGHELMRY
AAKLSDEAREIEKGLDQVMRMPHRASGELSVKRKLIEKLPPKA
>A0A166ABJ2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter oralis|TrEMBL
MVVKIGIIKSGNIGTSPVIDLLLDERADRPNIDVRVFGSGAKMNPEQVEDVVPKLDQFNP
DFAIFISPNPGAPGPAKAREILSEKGIPAIIIGDAPGKSKTDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNADILKVLANTGALRLVQKTIDAVIEGAEADNIELPKLIITAEKA
VAAAEFTNPYAKAKAIAAYEMAGAVANLDMKGCFMTKGYENFIPLVAAAHEMASAAASLA
HEAREIEKANDTVLRTPHMKEGNLGYKNCLISKPE
>A0A1Q9P7F1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thorarchaeota archaeon (strain AB_25)|TrEMBL
MSVTTINVGVIKLGAIASAPLLDLMFDERAERDDINVRAFTSGAKMDEESSTGPTESVIA
WAPHLVLVVSPNAALPGPTKVREMLHKAKLPTISISDGPAEKAFYKKNEEGKKKPHVLDG
QGFIVIPSDSMIGAKKEFLDPTEMSLFNADAIKVLSITGVARAIQNELDKVIAALQAGET
PEMPQVKLTAEKAVKCGYFKNPYAKAKAIAALTIAEAVADITAKGCFKTKEAEKYIPLVA
AGHEMMRVAANLSDEVRELEKAGDSVVRNPHVSKGKVKTKTALMDKPK
>A0A8G1A295|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanofollis formosanus|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVVNMKAWEP
DFCVVVSPNGILPGPTGAREQLAEAGIPCIVITDDVTGKKEQFAALKESQFGYIIMKADS
MIGARREFLDPVEMADFNGNLVKVLALTGAFRKLQFELDKVIDQVKEGKKGADLVLPKVV
MTSDKAVADEFSNPYAYAKARAAYEIAQAVAGVNVKGCFMTKGFENYVPIVASAHEMMRQ
AAYLCDEAREIEKAGDGIIRKPHKKDGVIVSKTTLISKPE
>A0A101IHI1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothrix harundinacea|TrEMBL
MFKIGFIKLGNVASSLVADLALDEIAERTDIEVRSLSFGAKMTKNEAEMSAELKSWGPQL
VVMVGPNAATPGPTAAREIYKDFPTVVISDGPSKKDAREALEAEGFGYIILPFDPLIGAK
REFLDPAEMALFNSDSLKVLSICGSVRLVQEELDRTMASILAGSAELPHILASPEKCTER
MEFKNPYARAKAIGALHMAQTVAGIAAAACFRLKELDRIALTAAAGHEVMRAAAKLADEA
REMEKAGDSVSRRPHARSGAILEKRGLLDKPDPI
>A0A7R9R924|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Methanoperedenaceae archaeon GB50|TrEMBL
MGNIGTSIVIDLLFDEIAQREDCETRTFSSGAKMSKKEAKETEELKGWNPDLVILISPNA
MAPGPVAAREIWKDVPTIVVSDGPTKKEGRQKLEDAGFGYIILTVDPLIGAKREYLDTVE
MVNFNSDVIKTLALTGAIRLVQETIDGVIEELKAGKTPTMPHILAKPEKCVEYGGFTNPY
AKAKALGALHILNKVAEINTPACFMMKDIVDITLTAAAGHETARVAAMLADEAREIEKSN
DTVSRKPHAKDGKILSKTRLYEKPQ
>A0A7C5U4K1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MGFTGKVRVAIVKYGCIGSSPLIEIMLDERANREDIVTRVFSTAGKMEVDDCLSVNGDVV
SFNPHLIVIVTPNAALEGPTKGRMDLKEKLPNVPIIVISDDPARKAIKDMEESGFGYIIV
KADPMIGARRDFLDSTEMVLFNGYLMIVLSATGVVRMLVSEIDKVIDAIKSGGEVKLPRI
VGEALFVVENYGGFTNPYAKAKAIASYEAAARVAALSTAGCYTLKEREQYLPMVAAAHEL
MRIAAILADEAREIEKYGDTVYRTPHISSGEVRFKVKLMEEAKKR
>A0A2L1C9V8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcus maripaludis|TrEMBL
MVVKIGILKCGNIGMSPVVDLCLDERADRNDIDVRVLGSGAKMGPEQVEEVAKKMVEEIK
PDFIVYIGPNPAAPGPKKAREILSAGGIPAVIIGDAPGIKDKDAMAEEGLGYVLIKCDPM
IGARRQFLDPVEMAMFNADVIRVLAGTGALRVVQNAIDDMVFAVEEGKEIPLPKIVITEQ
KAVEAMDFANPYAKAKAMAAFVMAEKVADIDVKGCFMTKEMEKYIPIVASAHETIRYAAK
LVDEARELEKATDAVSRKPHAGDGKILNKCKLMTKPE
>A0A843G4V1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter sp|TrEMBL
MVVKIAILRSGNIGTSPILDLLLDERADRPNIDVRVFGSGAKMNPEQVEDVVPKFEQFDP
DFCIFISPNPAAPGPARARELLSEIDKPAIIIGDAPGKGKKDEMDEQGLGYIIVMADPMI
GAKREWLDPTEMAIFNADIIKVLAETGALRLVQKTIDGVIEAIEAGNEVELPKLIVTAEK
AVEAAKFQNPYAKAKAIAAYEMAGAVAGLDMKGCFMTKGFENFIPLVAAAHEMAACAAAL
AAEAREIEKSNDTVLRTPHMKEGNVGCKLDLISKPE
>A0A2H6JU98|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|archaeon BMS3Bbin15|TrEMBL
MVKLLVIKIGNIATSLVLELLLDERADRKDIEVDVATTGAKMTPGDAERVLARVNLDEYN
LIIYISPNPAIAGPEMIINALKGRNAIIIGDAPGVKIIKKLEEAQLGYLFILGDSMIGAR
REFLDATEMAIFNAEMLKVLSITGALRLVQEEIDKAVDALKKDEKYLPKLVVDTAEAVEA
AGFENPYAKAKAMAAYEAIKLIGKLNVKGCFMVKDAREYIPMVTSAHELLRMAGIYSDEA
REMEKTMDTLLRKPHSRSGELLKKRSLMEKPS
>D3E118|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter ruminantium (strain ATCC 35063 / DSM 1093 / JCM 13430 / OCM 146 / M1)|TrEMBL
MVVKIGIVKSGNIGTSPVLDLLLDERADRPNIDVRVFGSGAKMNPEQVEDVVPKLDQFDP
DFCIFISPNPGAPGPARARELLSEKDLPAIIIGDAPGKGKKDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNADILKVLAETGALRLVQKTLDAVIAAADAGEEIELPKLIVTAEK
AVEAAGFANPYAKAKAIAAYEMAGAVAGLDMKGCFMTKGFENFIPLVAAAHEIASAAAKL
AQEAREIEKSNDTVLRTPHMKEGNLGCKVDLISKPVDK
>A0A6J4K2C2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured Gemmatimonadaceae bacterium|TrEMBL
MKKLLLQLDSSPLPSVFDRVVGFDGGADEIMSYGGVTEDAVRDLVHGAIFTRGPKDLKHT
AIFIGGADMAAGERLLAAARKAFFAPFQVSVMLDSNGSNTTAVAAVVKMIEAAGDVRGKR
VVITAGTGPVGTRAAGLFAQAGAHVVITSRKPEEGERTVAAIIARFGGTVEARTMRDTAQ
AADALEGAELLLNAGPAGIMLVPRAAWANRPGLRVAVDLNAVPPLGIEGIEVGDSAVVRD
GVTTFGAIGIGNFKMKVHKACIARLFERSDVVFDAESVAEVARELVGAGR
>A0A6J4MD25|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured Gemmatimonadaceae bacterium|TrEMBL
EKASAATRQLAAAERLRPRGGLRRWRRRGHELRGRDRGRGARPGARPHLHARPQGAQALR
RLGGRRRHGRRGAAARRRAPDGLPAVPGVGDARLQRVEHHRGGGGGEDDRDRGRRARPPR
GDHRRHGAGGHARRGAVRAGRRRGGDHLAQARGGRAHGGRDRPAVRRPGHRARRADARQL
AGGRGARGRGAAAQRRARGDHARAARGLGQPPRAQGGGRPQRRPPARRRGDRGARQRRRP
RRRHHLRRHRHRQLQDEGPQGVRRAAVRAQRRRLRRRDRRRGRARAGRPQGL
>A0A1V5SSH7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Euryarchaeota archaeon ADurb.Bin294|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVTNMKAWGP
DFCIVVSPNGVLPGPKGAREALAAAGIPCVVITDDITTKKEEWEALKASEFGYIIMKGDS
MIGARREFLDPIEMADYNGNLIKVLSITGAFRKLQVALDEVIDQVKAGKKGKDLALPKLV
MTSDKAVEGEFSNPYAYAKARAAYEIAQAVAGVNVKGCFMTKGFENYTPIVASAHEMMRQ
ATLLCDEAREMEKATDAVIRKPHKNDGTRVAKKTLISKPE
>A0A1V6N234|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter arboriphilus JCM 13429 = DSM 1125|TrEMBL
MVVKIGIIKSGNIGTSPVLDLLLDERADRPNIDVRIIGSGAKMNPEQVEEVTPKVKDFDP
DFAIFISPNPGAPGPAKARELLSGYDIPAVIIGDAPGAGKKDEMDEQGLGYIIVKGDPMI
GARRELLDPTEMASFNADVIKVLALTGAYRVVQNAIDALIEAAEAGKELELPKIILTAEK
AVESAGFTNPYAKAKAIAAYEAAGKVADIDTKGCFMVRDANQYIPLVAAAHELIGTAAKL
ATEAREIEKANDSVLRTPHAGDGSIVSKTKLLDKPS
>A0A7L4NVR9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacteriaceae archaeon|TrEMBL
MVVKIGIIKSGNIGTSPVLDLLLDERADRPNIDVRIIGSGAKMNPEQVEEVVPKVKEFEP
DFAIFISPNPGAPGPAKARELLSTYDIPAVIIGDAPGAGKKDEMDEQGLGYIIVKGDPMI
GARRELLDPTEMASFNSDVIKVLALTGAYRIVQNTIDGIIAAVDAGEDIELPKVIITAEK
AAEAAGFTNTYAKAKAIAAYTAAEKVADIDLKGCFMVKDSNQYIPLVAAAHELIAVAAKL
AVEARDIEKGNDTVLRTPHGSDGSTVTKTVLLEKPQ
>A0A833DVA6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus profundus|TrEMBL
ACFVEKDPKKYIPMVCAAHEMMRIASKLAEEAREIEKSNDSVFRNPHAKDGRILSKIKLM
DKPT
>A0A075WJ58|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus fulgidus DSM 8774|TrEMBL
MVVKVGVLKMGAIGTALLVEYLLDERADREDIEVRVVTSGAKMQPEEAVVAEKLKEFDPD
VVIVVSPNAALPGPKAAREAFEGKPVIVISDAPAKKAKDELKEKGFGYILINADSMIGAR
REFLDPTEMALFNADVVKVLAATGAFRLVQEAIDKVIEDIKAGKQPELPQIVVTAEKAVE
AGKFSNPYAKAKAMAAFYIAEKVADIDVKGCFIEKDPEKYIPLVASAHEMMRIAAILADQ
AREIEKSNDTVFRNPHAKDGKILGKTQLMAKPE
>A0A0J1EAE7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Rhodopirellula islandica|TrEMBL
MPKNILFQLDVDPHPSSFDAVVAVDAGVDHLFQYGSVQADSVESLVHGAMFTRGGDDLKH
SALFIGGNDVVQAEAIFRRVQKAFFGPVRVSVMLDASGCNTTAAAAVASASKHVTLDGCT
AVVLGGTGPVGRRVAQMLARQNANVLLTSRSLNRAETACQEIGVHVRSGNLEAAAPEKED
DLKALLERADVIIASGAAGVELASRELILGLTKLRVAIDLNAVPPAGLGGVEAFDKSKPL
HESQADGPVAYGPIGVGGLKMRTHKAAIAKLFTSNSLVLDADEIYDLTMEQMNR
>N0BIS0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus sulfaticallidus PM70-1|TrEMBL
MVKVGVVKMGAIGTALLVEYLLDERADREDITVRVVTSGAKMQPEEAEIVEKMKEFDPDL
VIVVSPNAALPGPKAAREAFEGKPVIVISDAPAKKAKEEFEEKGFGYILVNADSMIGARR
EFLDPTEMALFNSDVVKVLAATGAFRLVQEEIDKVIEALKEGKTPELPKIVVTAEKAVKA
GNFKNPYAKAKAMAAYYIAEKVADIDVKGCFIERDPEKYIPLVAAAHEMMRVAAIEADRA
REIEKGGDSVYRNPHAKDGKILSKTSLMEKPQ
>A0A166CNE9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter curvatus|TrEMBL
MYIYKKCDNMVVKIGIIKSGNIGTSPVLDLLLDERADRPNIDVRVIGSGAKMNPEQVEEV
TPKVKEFNPDFAIFISPNPGAPGPAKARELLSSYDIPAVIIGDAPGAGKKDELNEQGLGY
IIVKGDPMIGARRELLDPTEMASFNADVIKVLALTGAYRIVQDAIDDLVDAADAGKELEL
PKIIITAEKAAEAAGFTNTYAKAKAIAAYTAAEKVADLDLKGCFMVKESDKYIPLVAAAH
ELIGVAAKLATEARDIEKSNDTVLRTPHGANGSTVKKTVLLEKPV
>A0A843HCB6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosphaera sp|TrEMBL
MIKVGVVKVGNIGISTIIDLILDERADRDDFHIRTISTGAKMGQNEVNDVIRRVKRIDVD
LLVFISPNPGARHIKHAIEEITKLHLPLVIIGDKPGERAIPFMKELHLGYILIRADAMIG
ARREFLDSTEMTLFNSYVLNVLSITGVIRLLHEEIDKVLYSVKADTPIEFPEIIVTAQKA
VSYARFNNPYAEAKAMAAYQIAAQVSEMDVTACFWV
>A0A0K8P4Z4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Ideonella sakaiensis (strain NBRC 110686 / TISTR 2288 / 201-F6)|TrEMBL
MERPYILHMFTPGAQMSPFDVNMAADAGYQVITPYCGVTLEQVTGLTQDAIFSRGPKGVA
RTGIFIGGRDVLLAADMLERARAALVPPFQVSLFADPSGSYTTAAALVAATEAALRRHHG
LALRGLRVLLLGGTGTVGRIAGVLCAREGATAVLSSHKGLAAAQAAAGQTGARFGVTLEA
VSGHTDAERRAAIAEADVVMGVAAAGVQVMTAADRAIAARLRVAADVNAVPPEGLAGVGV
MDDGRPLEGTAAVGLGALAIGNVKYQVQHRLLVRMREAKPAVCFGFDDAFAVAREVLAGP
AGGAGG
>L0KTR5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomethylovorans hollandica (strain DSM 15978 / NBRC 107637 / DMS1)|TrEMBL
MAKIGIIKLGNLGMSQVVDLVQDEIAAREGITVRVFGTGPKMGKDEAAATADLKKMEADF
YVMISPNSSAPGPTAARELYKDVPCIIISDGPTKKEDREALQQAGFGYIIMTVDPLIGAK
TEFLDPVEMASFNSDAMKVLSTCGVVRLIQEELDKVAALVDAGEPIQLPHILAKPEVCIE
RAHFNNPYAKAKGLAALHMADMVAKINFPACFMMKELEQVALTTAAGHEMMRAAAQLAIE
AREIEKANDSVFRQPHSKKGGKQFQKTKLYEKPQ
>A0A7C3TLV0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Nitrososphaerales archaeon|TrEMBL
MVIKIGFVKIGNIGSAPILELLLDERAEREDIDVRVVTSGAKMGVDQAEEISKKMVDYKP
NFVVTTSPNATLPGPSKIREILKEAGIPLIVISDSPAKKAIKQIEDMGQGYIIVEADSMI
GARKEFLDPVEMALFNADLIKVLSITGAFSIIYTEMDKLINAFKKGETPALPRIVIDKER
AINAAGFQNPYARVKAMAAYEIARRVADLSVEGCFMVKEWERYTALVAAAHEMMRTASIL
ADEAREIEKNSDAVLRMPHHSDGTVMQKRKLIEKPRKPGE
>A0A7C5XPH2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKEVIRVGFGKLGCIASSPLIEYLLDERADRDDLSVRVVSSGAKMGETDAEDVAKALIEF
KPDLAVAVSPNAGLPGPRKMRILLKNAGIPTIVVSDAPSRRIVKELEDDGYGYIIVLGDS
MIGARREFLDPIEMAIYNADLIKVLAITGAFRVIQLELDRVIDALKKGEELKLPRIIVDR
KVAVEAGRFANPYARVKAIAAYEAATKVADLTVEGCFKIEEWTEYTSIVAAAHELMSYAA
KQASEAREIEKGLDTVYRAPHSRKGEVLSKRKLIEKPSKPG
>A0A842QXW5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MSDEKFKLGVILVGNIGMSPLLAMIIDERADRKDLDTVVASSGAKLGKEECIKTTKKIID
EQPDLILWSSPNAALPGPKKSRDLLQETGIPTIIISDAPSKKASDEIKERGMGYFVIPAD
SMIGARREFLDPTEMVSFNADLLKVLAFTGIVKLVVTEIEKVITAIKQGSTPELPTILVK
KENALDAAEYRNPYAMAKAMAAHEISVAVSKLNTEGCFKTKGRENYMPIITAAHEMMRIA
AFLCDEAREIEKGTGLVHRAPHYKDGHVMTKTGFLDKPE
>A0A497MBC6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVVKVGFAKVGNIATAPLIEFLLDERADRNDIDVRVVSSGAKMGVEQAEEVAKKLLEFKP
DFAVVTSPNATLPGPKRLRELLAEGDIPVIVVSDAPAKKIVKKLQEAGFGYIIVTADAMI
GARREFLDPVEMALFNADLIKVLAVTGVFNIVQVELDKVIDAFKNGEKPTLPRIVIDKDK
AVEAANFSNPYAKAKAMASFEIARRVADLTVEGCFMVKEWERYTLLVAAAHEMMKTAAKL
ADEARELEKATDNVYRSPHNRAGLILSKRKLIEKPAKPV
>A0A7J3W749|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVKVGFAKIGNIGSAPMIEFLLDERADRNDVDVRIVSSGAKMGIEQAEEVANKLLEFKPD
FVVVTSPNASLPGPTRLREILAEKNIPVIVVSDAPAKKIAKDLQSKGFGYIIVMADSMIG
ARREFLDPVEMSLFNSDLIKVLAITGVFNIIQVELDKVIDAFKQNVKPTLPTIIVTKDNA
VEAAKFSNPYAKAKAMASFEIARVVADLTVEGCFIVKEWERYTAIVAAAHEMMRYAAKLA
DEARELEKSNDSVYRAPHSKAGVILSKRKLIEKPAEQV
>A0A7J3I4N1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
EKYIPIIAAAHELMRQAARLADEARELEKSGDTILRMPHRKSGEIASKRKLLEKPA
>A0A497JLZ9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MSPTPVKVGILKLGCVGTAPLLEYLLDERADRGDIKVRVVGSGAKLDPEEAEDAAKGMLN
FKPDFAIVVSPNAALPGPTKAREILKEAGIPVIVVSDLPAKRATKDMEAKGFGYIVVEAD
AMIGARREFLDPVEMACFNADIIKVLAVTGVYNLLVKNIDSVIQAFKEGKQPELPKIVVD
RAKAIKEAEFQNPYASAKAMAAFEAAKKVADLTVEGCFKIQDREVYIPIVASAHELMGYA
KKLVEEAREIEKQGDTLVRKPHAKDGTLLAKVRLMEKPEKK
>A0A3R7C6R1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MSSIVKVGVLKIGCIGTLPLLDVMLDERADRQDIDVRVIGSGVKLGIDQCREVTDLMIKQ
NPDLVILIGPAQATQGPTKARKMLSEAELPTIMISDSPAKRLVDEMEKAGLGYIIVEADS
MIGARREFLDPVEMTLYNSDVIRVLAVTGAFNIVVEAIDEAIESIKQGEKPKLPQLIIDG
TKAVEAAGFTNPYAKAKALAAYEMARQVSRLTTTACFKIHDPSLYIPMVAAAHEIMRTAA
KLADEAREIEKSQDKVLRRPHFKNGKIGTKRSLMEKPLKDI
>A0A832SGF0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina acetivorans|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMGPADAADTESFKQWNADF
VVMISPNAAAPGPTAAREIWKDVPCIVVSDGPTKKEAREALEQEGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSSCGVVRLIQEELDRVTEQVASGKSGEDLELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEVEQVCLTAAAGHEIMGAAAIL
ATQAREIEKSNDTVFRQPHAKNGTLLKKVKLYEKPE
>A0A8D6PWK2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocaldococcus sp. SG7|TrEMBL
MGETLVVKIGVIKCGNLGISPMIDLALDERADRKDIAVRVLGSGAKMDPESVEEVTNKMV
NEIKPDIIIYVGPNPGAPGPKKAREILSKSGIPSVIVGDAPGLKVKDEMEQQGLGYIIIK
CDAMIGARREFLDPVEVAMFNSDILRIIGGTGALRIVQNAIDEMITAIKEGKHVELPRIV
INEEKAVEAMEFTNPYAKAKAMAAFVIAEKVADVDVKGCFMIKDAERYIPIVASAHEMLR
YAAKLVDEARELEKAMDAVSRKPHASDGRILSKKKLMEKPQ
>A0A662U805|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thermoprotei archaeon|TrEMBL
MSEEGKVVKIGIIKPGAIGTSVILEYLLDERADRKDVDVRVYGTGAKMVVDENLLKAAIE
ANHDLYIVAAPANVKIIKKIAKKLKEAGKRVIIISDEPTKKAAKDFEAEGYGYILVYGDP
MIGARREFLDPTEMALFNSYVLGVLSATGALRIVTEAIDKVIDALKKGEEPELPKLKIDK
NAIEKYGGFTNPYAKAKAIAAYEIARRVASLTTEACFVIQEPERYIVTAAAGHEMLRIAA
KLAEEARELEKAEDIILRTPHHPTGRTLTKKKLLEKPG
>D1JH91|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon|TrEMBL
MQVVKIGFVKLGNIGASRIVDLLLDERADREDIDARVLGTGAKMTPEHAADTSRLLDWDP
DLVVITSPNAALPGPKRAREMVKEKGKPCIVISDAPAKKAVNDLKENGYGYIIIPGDPMI
GARREFLDPVEMSLFNADVLSVLTIAGVVKLMQEELDAVIDAIRKGGDVKLPQIIATAEK
SVERAQFSNPYAKAKAIAAYSMAEKVAELDVKGCFMMKDPKEYVPIVAAAHELLREAAKL
AYEARDMEKQTDSLVRMPHARTGEILKKEKLLEKPSA
>A0A0E3RKA4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina mazei LYC|TrEMBL
MKKMVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMAPADAADTESFKQWN
ADFVVIISPNAAAPGPTAAREIWKDVPCIIVSDGPTKKEAREAFEQEGFGYIILPVDPLI
GAKREFLDSVEMASFNADAMKVLSICGVVRLIQEELDKVTEQVASGKSGKDLELPHIFAK
PEKCVEHAGFANPYAKSKALAALHMAEKVAQVNFPACFMLKEIEQVCLTAAAGHEIMGAA
TQLANQAREIEKSNDTVSRMPHAKNGAVLKKVRLYEKPE
>A0A847V3V8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothrix sp|TrEMBL
MFKIGFIKLGNVASSLVADLALDEIAERTDVEVRSLSFGAKMTVKEAEMSAELKGWRPQL
VVIVGPNASTPGPTAARALYREVPTIVISDGPSKKEAREALEAEGFGYIILPFDPLIGAK
REFLDPAEMALFNSDALKVLSICGSVRLVQEELDRSMASIVSGSPTLPHILASPEKCTER
MDFENPYARAKAIGALHMAQTVAAIDAAACFRLKEMDRIALTAAAGHEVMRAAARLADEA
RELEKSTDSVSRRPHSRSGAILAKTGLLDKPEPV
>A0A843L9Z0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothrix sp|TrEMBL
MFKIGFVKLGNIATSMAIDLSLDEIAERTDIEFKIISFGPKMTRKEGEAAAELLAWQPQL
VVISSPNAATPGPAAARELFRGTPTIVISDGPSKKEARDALAAEGFGYIILPMDPLIGAK
REFLDPAEMALFNSDALKVLAACGAIRLVQEELDSAMASIASGAPSLPTILATPEKCAER
MNFTNPYARAKAVGALYMAQAVAGIDAAACFRLKELPAIALAAAAGHEVMRAAARLADES
REMEKANDSVSRRAHARSGELLSKKGLLDKPEKQ
>D3S659|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocaldococcus sp. (strain FS406-22)|TrEMBL
MVVKIGIIKCGNIGMSPVVDLALDERADRKDIAVRVLGSGAKMDPESVEEVTKKMVEEVK
PDFIIYIGPNPAAPGPKKAREILSQSGIPAVIIGDAPGLRVKDEMEQQGLGYIIIKCDPM
IGARREFLDPVEMALFNSDVIRVLAGTGALRIVQEAIDKMIDAVKEGKKPELPKIVITEQ
KAVEAMEFTNPYAKAKAMAAFVIAEKVGDVDVKGCFMTKEAEKYIPIVASAHEMIRYAAK
LVDEARELEKAMDTVSRKPHHPEGKILSKKALMEKPQ
>A0A524L9T1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thorarchaeota archaeon (strain OWC)|TrEMBL
MSDLCRIGILKIGCIGAAPLIDLILDERAERKDIAVRTVTTGASMDPMHSEEATAKIAEM
NPGLVIIVSPNAALPGPTQAREYLMKMKLPVLSISDAPSKKAFYTKDEKGKSVASAPAGS
GFIVLPMDPMIGARKEFLDPTEMALFNAELIKVHSCTGVTRFLQSEIDKLTDSLKAGTEL
KLPTITLKIEKA
>A0A497HLP9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thermoplasmata archaeon|TrEMBL
MIGARREFLDPIEMAIFNSDMLKILSVTGALRAVYEAIDQTISSLKEGKKNLPRIVFDKD
GVMGYSGLKNPYALSKAIASHIIAEQAGKLSIEACFKTHNPEEYIIKSSSSHEMIRISSK
LAEEAREIEKTNDSVLRNPHTKEGRILSKRKLLEKPK
>F7XNL9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosalsum zhilinae (strain DSM 4017 / NBRC 107636 / OCM 62 / WeN5)|TrEMBL
MAKIGFIKLGNLGISQVIELVQDEIAAREGISIRVFGTGPKMGKDEAASTEQFKDMSWDA
DFYVIISPNASAPGPTAAREIWKDVPCIIVSDGPTKKDDRQALEEAGFGYIILKVDPLIG
AKTEFLDSVEMASFNSDAMKVLSTCGVVRLIQEELDKVVEQVDAGKSGSDIELPHILAKP
EVCVERAGFENPYAKAKALASLFMAEKVAQINFPACFMMKELEDVALTTATGHEMMRAAA
ELAVQAREIEKINDTVSRHPHSKKGKVLSKTRLFEKPA
>A0A7J3I645|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Ignisphaera aggregans|TrEMBL
MSQSEVTKTVKVCILKLGCIASAPLLEYILDERADRMDIEVRVVTTGAKMYDEKYGLELA
EKGFREDCDIYLVVSPNATTPGPTKARETLKEKGKHVIVVSDAPTSKIVKDLEAKGFGYI
IVLADSMIGARREFLDPVEMTLFNGDLIRVLAITGVYRLLQREIDNVIDQIKKGITNIQL
PKIVVDKETAVRYAEFRNPYAKVKAMAAYEIARHVADLTTEGCFRVKEADRYIPIVAAAH
EMMRYAALLADEAREIEKYGDTVVRTPHSTKGEVLFKEKLAEKPVKKE
>A0A177IWF3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methylorubrum populi|TrEMBL
MARSILHMLTPLKHMSPFDVNMAIDAGFETLIPYTNVDLADVVSLTQDSIFSRAPQDGVR
TGIFIGGKNAELALDMVDRAKKAFVPPFVNHVFADPAGSFTTGAAMVAEVNRALKARFST
DLKGKRIVIFGGAGVVAYVAAVIGALEGAQTVLVGHDGEERVSKIAFTMKWRFGIEVGAV
DGTAPEARRAAITDADVILSAGPAGVSILTAEDLESAPKLLVASDVNAVPPAGIAGIDVN
AVDVALPVGKGVGIGALAVGNVKYQTQCRLFRQMLEAQEPLCLDFRDAYKLAVEIAG
>A0A2A2HDM5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosphaera cuniculi|TrEMBL
MVIKIGILKIGNIGTSPVVDLILDERADREDIDVKTFSSGAKMGKNEVHNIMPYIIENEF
DLIIFISPNPSVGGPKLAREVLSEIKTPSIIIGDSPGIRCIDEMKQQNLGYILIKGDPMI
GARREFLDPTEMAIFNADIIQVLAITGVFRLIHTKIDEIIEQIKNEKTITLPEIIIEAED
AVDMAGFNNPYAKSKAIAAYKIACDVSEIDATACFKIKDPNRYVPLVSSAHEMITTAAKL
AREARELEKSYNSVLRTPHKRNGSYEIRNKLID
>A0A7C0VRR8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MADVKIGFVKLGNLGMSQVIDLVLDEIAARKGIMVRTMGTGAKMGADEAKDTEALIKHWD
PDFVVMISPNASAPGPTAAREIYKDTPTIVVSDGPDKKDARQALADAGFGTIILKVDPLI
GAKREFLDPTEMASFNSDAMKVLSSCGVVRMIQEEFDKVIDQVASGKSGKDLELPHILGS
PEKCVERGCFENPYAKAKALAALHMANTVAAINFPACFIHKDVEKVTLTAAAGHEMMSAA
AVLAREAREIEKSNDTLFRQPHAGAGNLLTKSKLYDKPE
>A0A662RQF3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MEVVKVGFVNLGNIGTARIVDLLLDERADREDIDVRMLGTGAKMTPENAADTSRLLEWNP
DIVVITSPNAALPGPKSAREMVKEKGKPCIVISDAPAKKAVDKLKKEGFGYIIIPGDPMI
GARREFLDPVEMSLFNADVLSVLSITGVVKLVQEEIDGVIDAIKKGEEVKLPQIIATAER
AVERANFSNPYAKAKAIAAYSMAEKVAELDVKGCFMMKNPEEYVPVVAAAHELLREAAKL
AFEAREIEKQADSLVREPHSRTGEIMKKKKLMEKPSA
>A0A8B6SDG8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Argoarchaeum ethanivorans|TrEMBL
MVKVGFVKMGNIGTSLAIDLLFDEIAEREDINTRTFSSGAKMGKEEAYDTKHFKRWYPDL
LIMVSPNPNAQGPAEARRIWKDVPTILVSDGPTKKDERQKLADAGFGYIILPVDPLIGAK
REYLDTVEMVNFNSEVNKTLAFTGAIRLVQETIDGVIEEIKAGETLNLPHILAKPEKCIE
YGGFSNPYAKAKALAALHILLKAAEINSKACFGMKGIEAITLTTAAGHEMVRTASMLADE
AREIEKCNDTVSRKPHARDGRILSKTRLYEKPE
>A0A3A5HPV7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium sp|TrEMBL
MVVKIGIVKCGNIGTSPVLDLLLDERADRPNIDVCVVGSGAKMNPDEIEKAVPLMLEMDR
DFVIFISPNPGAPGPAKARELLSAADVPAIIIGDAPGLRSKDEMEEQGVGYIIVKADPMI
GARREFLDPTEMASFNADVIKVLALTGAYRVVQNTINAAIAAVEAGNEIELPKVVISRDV
AVEAAQFASPYAKAKAMAAYEIATKVADIDVEGCFMVRDAEKYIPIVASAHEMITVAAKL
AEEAREIEKANDTVVRTPHGGDGQTMSKADLMSKPQ
>A0A328SP66|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosphaera sp. rholeuAM130|TrEMBL
MIKVGVVKVGNIGVSTVIDLILDERADRDGFHIRTISTGSKMGQNEVNDIIRRVKKIDVD
LLLFISPSPGARQIRHAIDEISKLDLPLIIVGDKPGENAIPFMKERNLGYILVRADAMIG
ARREFLDSTEMAVFNSYVLNVLSITGVIRLLHEEIDKVLDCVTNDEPIAFPEIIVTAQKA
VSYARFSNPYAEAKAIAAYQIASQVSEMDVTACFRVSDPKEYIPLVVAAHEMMKSAAILA
EEARELEKSNDTVTRTPHKRDGSVVFKSKLLHNFEDEDTFEKDWFI
>A0A7L4P3R2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacteriaceae archaeon|TrEMBL
MVVKIGVIKCGNIGTSPVLDLVLDERADRPNIDVRGVGSGAKMNPEQIEEVVPKIADFDP
DFVIFISPNPGAPGPARARELLSEMDVPALIIGDAPGMGKREEMDEQELGYIVVLGDPMI
GARREFLDPTEMASFNADVIKVLAATGAYRVVQETIDGMIAEAEAGKEITLPKVVIDAAK
ATDAAGFSSPYAKAKAMAAYEMAAKVGDIDLKGCFMVKEMEKYVPIVASAHELISAAAKL
ATEAREIEKANDTVLRKPHGAQGQTLSKTALISKPE
>A0A832VTW4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacteriales archaeon|TrEMBL
MVAKIGVLKCGNLGTSPVIDLVLDERADRPNVEIRVMGSGTKMNPDDIEFVVPKMLELDR
DFVIFISPNPGAPGPARARELLSEADVPAMIVGDAPGLRVKDEIEEQGLGYIIVKADSMI
GARREFLDPTEMAAFNADLMKVLALTGAYRVVHNTIDAMIADVEAGKEIELPQLVITRDV
AVEAADFQNPYAKAKAMAAYEIASKVADIDVEGCFMVQDPEKYIPIVASAHEMMSTAARL
AEEAREIEKSNDTVRRTPHGKEGETLSKRKLLEKPS
>A0A133UGS7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|candidate division MSBL1 archaeon SCGC-AAA259E17|TrEMBL
MNEKIRVGFVKLGNIGTSTMLDLMLDERAEREDVDFRVVTSGPQMTEENGREVSKKVLDF
DPNLILTASPNPTTPGPSAAREVLEDVDVPCIVIGDAPGAKISEELEEKGFGYIFINADA
MIGARREFLDPVEMALFNSYLIKTLAVTGALSAVQEEVDLTISKIKEDERYLPQLIVDRD
KSIDVAEFENPYAKTKAMAAFEIASKVADLTFEGCFKIQESEKYIPIVGSAHEMMRVAAK
LSDEAREIEKGENSVLRKPHYDDGSILRKRKFLASPE
>Q46DH9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina barkeri (strain Fusaro / DSM 804)|TrEMBL
MVNIGFIKMGNLGMSQVINLVQDEIAAREGITVRVFGTGAKMSPAEAAASESFKQWNADF
VIIISPNAAAPGPKAAREIWKDVPCIVVSDGPTKKEAREALENNGFGYLILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLVQEELDKVTDQVASGKSGKELELPHIFAKPEK
CVEYAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAASQL
AIQAREIEKSNDTVLRQPHAKNGTLLKKVKLYQKPE
>T2GKI7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermobacter sp. CaT2|TrEMBL
MVVKIGIIRCGNIGTSPVLDLLLDERADRPNIDVCVVGSGAKMNPDEIERAVPTMLEMDR
DFVIFISPNPGAPGPAKARELLSEADVPAMIIGDAPGLRVKDEIEEQGLGYIIVKADPMI
GARREFLDPTEMASFNSDVIKVLAFTGAYRVVQNTIDAMIADVEAGKAPELPQVVIDTDV
AVEAAGYENPYAKAKAMAAYEIATKVADIDVKGCFMVQDPDKYIPIVASAHEMLAAAAKL
AVEAREIEKANDTVLRTPHGKEGETLSKTDLLAKPE
>A0A7C1DVN4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoculleus sp|TrEMBL
MVVKVGVAKLGNIASGVMVELLLDERADREDMITFMATSGTKLQPEDVDRVVSNLKAWGP
DFAIVVSPNGVLPGPTGAREALADAGIPVIVITDDVTTKKEWADLKESKFGYIIQKAD
>A0A2H4U8H2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter smithii|TrEMBL
MVVKIGIIKSGNIGTSPVLDLLLDERADRPNIDVRVFGSGAKMNPEQVEDVVPKVDQFDP
DFCIFISPNPGAPGPAKARELLSEKDIPAIIIGDAPGKGKKDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNADILKVLAETGALRLVQNTIDGVIDGAAAGNIELPKLIITAEKA
VEAAGFENPYAKAKAIAAYEMAGAVANLDMKGCFMTKGFENFIPLVAAAHEMAASAAALA
DEAREIEKGNDSVLRTPHMKEGNTGRKTDLISKPE
>A0A7C4GTE3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKVGIFKCGNIGTAPLLELLLDELADREDISVRVITTGAKMLAEEVEEALPKMFDFNPDF
IVFISPNPAVQGPKRAREILLEKKVPSIFISDAPGKRLKEEFEAQGFGYIIIMGDPLIGA
RKEFLDPTEMAVFNSNIIKVLAITGVYKIIQQEIDRIIQCCKEGLTFQLPRLIIDTDTVR
DYSDFRNPYALAKAMAAYELTKKVAEINARACFMEKEKEKYILLVACAHEIAEVAARLAE
QAREIEKYADSLVRRPHSKEGKLKIKERLMDSPIFEEVFR
>A0A7C3XJJ3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MPEPIRIGFIKLGNIGTAPLVEFLLDERAEREDISTRTIGSGSKIGPVEAEEVAKKLLEF
KPQIAIVLSPNAALPGPTKARQVVAEAGVPTIVISDGPTKKALKQLEEGGFGYIIVEGDP
MIGARREFLDPVEMAIFNSDILKVLSATGVLRIVTDEIDRAIESLKRGERPALPRVIVDK
ERAAEAGGFSNPYAKAKAIAAYEISCRVAAVTTEACFVIKEWERYTTIAAAGHEMMRCAS
KLAEEAREIEKGDDSILRTPHFDDGTTLSKKELLEKPRRAG
>A0A846PJT4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MPDKNLESEIITAGIFKCGNIASSPLFELLLDELADRKDIKTRTVSTGSKMGVEDVEEAL
PKIFDFKPDFLVLISPNPSIRGPAIAREKSSKSGLPVVIICDAPGKRITAELEEQGLGYI
IVMGDPLIGARREFLDPLEMAIFNANIIKVLAITGVYRIMHHEIDKIVCTLMTKSRLVLP
RLVIDVDVIRERSDFANPYAEAKALAAYGLTEKIAEINFQACFHEKESRRYIPLVASAHE
IAQVAAKLAEEAREIEKYGDTLVRKPHTKKGDLKVKTKLMHSPTRGEGVY
>A0A7J3IFF6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MSEVVKIGVLKAGCLGSLPLLEFILDERADREDIQVKVVGSGSKVTPEACIEGAEYILKM
NIDLIIFIGPAQTTQGPAEARKILRSSNKPVIVISDSPARRIIKELEEYGFGYIIVEADS
MIGARREFLDPVEMALYNSDIIRVLAVTGVLNIIVEELDKAINAIKYGEKPPLPKLIVDS
RRAVEAAGLSNPYAKAKAIAAYELAKQVSNITFEACFKLHEPEEYIPLVAAAHEIMRVAA
RLADEVREIEKSGDSVLRKPHFRDGTRGEKRLLMEKPVKSPRLR
>A0A419JSC3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MPKNVKIGVLKLGCVGTLPLLDVLLDERADRTDIDVRVVGSGSKLGPQQCKEATELMINL
KPDIAVLVGPAQAAPGPTESRKMLKAAGLPVIVISDSPAKKLVKDIDEAGQGYIIVEADS
MIGARREFLDPVEMAIYNSDVIRVLAITGVFNIVVETIDKVIQSLKAGKTPELPKIVING
EKAVEAGGFSNPYAKAKAMAAYEMACQVSKLTTRACFKVSDREVYVPLVTAAHEMMRTAA
RLADEAREIEKTGDTVSRKPHFKDGTLGTKKTLMEKPKRIK
>A0A497EX71|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Verstraetearchaeota archaeon|TrEMBL
MSEKVVKISIIKVGCIGCSPLLEYLLDERADRTDIDVRVFGSGSKLDEVRAEDVAKRALE
FNPDLVIISTPNAALPGPTKARNIVKEKEIPCIVIADAPTKKVKDKLKEEGFGYIIVEAD
SMLGARREFLDPIEMAVYNADLIKVLAITGAYRIVYESIDKVIEALKKGEKPELPTIIVK
ADNAIKAAEFNNPYAKAKAYAAWEMSKRVADLTTKACFVIKEWEVYTSLCASAHELMREA
AKLADEAREIEKYGDQLVRKPHSKAGVVLRKVKLIEKPQ
>A0A497N391|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MIRVGFLKLGNIATAPMIELLLDERAEREDIEVRVVTTGANMSPEQAEEAAKTMLSLKPQ
IVFITSPNASTPGPKRAREIISGEGVPTVVVSDGPKKIVESLAKKGIGCIIVEADSMIGA
RREFLDPVEMALFNSDVIKVLAVTGAYTLLFKTIDGLITDLKEGREPKLPSLVINSALAT
EAAGFKNPYAKAKAYAAYEIARRVSSLTTEACFKVKEWEVYTSLCAAAHEMMRIAASLAD
EAREIEKYGDSVLRMPHYDDGTILVKRALIEKPKGK
>A0A7K4BF71|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMITFMATSGTKLQPEDIDRVVNNMKAWAP
DFCIVVSPNGVLPGPTQAREGLAAAGIPCVVVTDDITTKKEQFAALKESEFGYIIMKADA
MIGARREFLDPIEMADYNGNLVKVLALTGAYRKMQLELDKVVDQVKEGKKGKDLVLPKVV
MTADRAVEGEFSNPYALAKARAAYEIAQQVAAVNVRGCFMVREWEKYIPIVASAHEMMRQ
AMVLCEEAREIEKAVDAVIRKPHKKTGEIVSKTQLVSKPE
>A0A532TRI4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon Loki_b31|TrEMBL
MSEEKVLKIGIQKNGTIGSSLLLAFLMDERAESTNIIVREVTSGAKMNPSEECVETMKKL
LEFEPELILMSSPNAALKGPKAARELAGIIPTIVISDAPAKKAIEEFKEKNMGYIIVGCD
SMIGARRPFLDAVEMSCFNADLLKVLAITGVFNIITNELNKVIMDMLEGKAPILPQIEIK
ATNATEAAGFSNPYAQAKAIAAFELAASVSKITGRACFVLKDRAEYMPLLAASHEMMKTA
AELCTQAREIEKSNDTVLRTPHHAKQHLLTKRKLHEKEA
>A0A3B1DE57|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|hydrothermal vent metagenome|TrEMBL
MKKILIQFDTDTNPSSFDRVVAVDSGVDELFSYGGIHKENVEALVHGAIFTRGVKDLHST
AIFIGGSDVSAGELLFDAVNKTFFGPMRVSVMMDSNGCNTTAVAAVLCAKKHLDLSTTKA
LVLGGTGPVGQRSAELLARAGAEVRVASRSLSRAEDVCNRIAALTETSLLTPCTLNNEAE
VNQVTEGVTLIIAAGAAGVQLLSAEQLSNIETLQVAIDLNAVPPAGLEGVSLTDKNENRS
GVFCYGPIGVGNLKIKIHKEAINQLFSKNDLLLDTTTIYNLGSEIDSI
>A0A3R9EKG9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanohalophilus sp|TrEMBL
MGNLGMSQVIDLVQDEIAAREGISTRVFGTGPKMDKETAASTDELKAWEPDFVVMISPNA
SAPGPKSARELWNDYPCIVVSDGPTKKDDRQALEDAGFGYIIMTVDPLIGAKTEFLDAVE
MASFNSDAMKVLSTCGVVRLLQEELDAVTAQVDEGKSGADLELPHILAKPQKCIERAGFN
NPYAKAKGLAALHMASKVAEVNMPACFILKEIEDVALTAAAGHELMRAAAQLAIEAREIE
KANDSVFRQPHSKKGAQLQKIKLYEKPQKV
>A0A0E3X043|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcoides methylutens MM1|TrEMBL
MAKIGFIKLGNLGMSQVIDLVQDEIAAREGISVRVFGTGPKMGKGEAAETEQLKEWDADF
YVMISPNSSAPGPTAARELYKDVPCIVISDGPTKKDDRQALQDAGFGYIIMTVDPLIGAK
TEFLDAVEMASFNSDAMKVLSTCGVVRMIQEELDAVAAQVDEGKSGKDLELPHILAKPEK
CIERAGFNNPYAKAKALAALHMADKVAQINFPACFMMKEIEQVALTTATGHEMMRAAAQL
AVDAREIEKANDSVFRQPHSKKGVQMTKTALYEKPQ
>D7GJ50|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Propionibacterium freudenreichii subsp. shermanii (strain ATCC 9614 / DSM 4902 / CIP 103027 / NCIMB 8099 / CIRM-BIA1)|TrEMBL
MDTTENRVPVQIGIFSVSDLTPDPTTGITPTEHERLKNYALIVKKAEEIGLDAFALGEHH
NPPFVSSSPTTTLGWLAAQTSKITLSTATTLITTDDPVKIAEDYAMLQHLADGRVDLMLG
RGNTGPVYPWFGKDIRQGINLALENYNLLHRLWREEVVDWQGKFRTPLQGFTAIPRPLDD
VPPFVWHGSIRSPEIAEQAAYYGDGFFHNNIFWTMNHTKRMVDLYRRRYEHYGHGRYDQA
IVGLGGQFFMRKNSQDAIKEYRPYFDNAPVYGHGPSMEEFTEYTPLTVGSPQQVLERTLS
FKDDVGHYQRQMFLIDHAGLPIKTVLEQLDLLGEILPEMRKGFLEGRPDDIPDAPTHASL
VAARDAAGVAPVEHVKVGADDVTGTSDAPEPPDSVFEK
>A0A524FCF1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MSEDKVLKIGILKNGTIGSSLLLAFLMDERAEGKRINVIEVTSGAKMHPPEICLPTIDKL
LEMNPELILMSSPNAALGGPKACREKANEAGIPTIIISDSPAKKAVDEIKEKGMGYILVN
CDSMIGARRPFLDPIEMSIFNADLLKVLAITGALKVIAEELNKVILDMLEGRTPTLPQII
IDSSIATEAAGFSNPYAKAKAIAAFELAASVSKVTAKACFVLKERAEYMPLLAAAHEMMS
TAALMCYEAREIEKANDTVLRKPHHTKQQFLTKRSLMDKEQ
>A0A1H7FCW2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter gottschalkii|TrEMBL
MVVKIAIIKSGNIGTSPVIDLLLDERADRPNIDVRTFGSGAKMNPEQVEDVVPKIDAFEP
DFAIFISPNPGAPGPAKAREMLSEKDIPAIIVGDAPGKGKKDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNSDILKVLAETGALRLVQQTIDTVIEQAEAGEIELPKLIVTAEKA
AEAGGFANPYAKAKAIAAYEMAGSVANLDMKGCFMTKGFENFIPLVAAAHEIAACAAKLA
QEAREIEKANDTVLRTPHMKEGNLGSKTDLISKPE
>A0A8J7ZB05|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Asgard group archaeon|TrEMBL
MKKKKVGILKFGNIASSVLLEMLLDERADREDIEVKTISSGAKLTLKSIKSAFEIFTSQS
FDLSIIATPNASLKAPLGIILELAKKVKHVIVLTDVVKKETIEEFKEKKIGYLIVKPDAM
IGARREFLDPVEMALFNADLIKVLAIGGVFNILYQEIDRVLEQIVQKDKVTLPYLTITPA
KAVKKANFSNPYAAAKAQAALEIAQAAAKVNTDGCFKINKRLEYIPQVATGHEMIQTAAT
LAESAREIEKANNKVQRKPHHYKGEIQEKRLLKEKPTSEY
>A0A843BPU3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Heimdallarchaeota archaeon|TrEMBL
MVKEKSAKKDVLVKKLGILKLGNIASSVLLEMLLDERADRLDIEVRTISSGAKLQKESIN
DAFEILSKLAFDLVVVATPNASLSAPLEIIKELGETKTPVIVLTDILKKETQEELKEKNI
GYLVVKPDAMIGARREFLDPTEMAIFNADLIKILSIGGALAAIQQEIDEALNLIISKKEI
ILPQIVLTPAKIVTYAGFANPYAEAKARGALEIAEKAAKVNTDGCFKISERSEYISQVAT
GHEMIRIAAKLADEAREIEKANNKVRRQPHSYYGEIQTKQLLKEKPDSNYE
>A0A524EMJ5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thorarchaeota archaeon (strain OWC)|TrEMBL
MTKDCTIGILKLGAIGAAPLIDLLFDERAERKDIAIRTVTTGASLDEEACQEAATRLAEM
TPDLVILVSPNAALPGPKGARTYLLDEEFKVLSISDMPSKNAFYSKDESGKKVPSVPETS
GFIILPMDPMIGARKEFLDPTEMTIFNADLIKLLSCTGVMRFLQYELEKLVDSIKTKSDI
DMPTLILTPELALEAAGFANPYAHAKAYAALKMAEAVADITTTACFMRKDPDEYVPMVAA
AHELLGTAAELAAYAREMEKAGNSVLRTPHSSSGKNLRKTELFEKPD
>A0A7R9R8Z0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Methanoperedenaceae archaeon GB37|TrEMBL
MGNIGTSIVIDLLFDEIAQREDCETRTFSSGAKMSKKEAKETEELKGWNPDLVIMISPNA
MAPGPVAAREIWKDVPTIVVSDGPTKKEGRQKLEDAGFGYIILTVDPLIGAKREYLDTVE
MVNFNADVIKTLALTGAIRLVQETIDGVIEELKAGKTPTMPHILAKPEKCVEYGGFTNPY
AKAKALGALHILNKVAEINTPACFMMKDIVDITLTAAAGHETARVAAMLADEAREIEKSN
DTVSRKPHAKDGKILSKTRLYEKPQ
>A0A523AVH1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Hadesarchaea archaeon|TrEMBL
MFSKVRIGVVKVGNIGTSTMIDLLLDERAEREDIDFRIVGSGPKMQEEDCKECAQKILEF
NPHLVLIVSPNPALPGPTAARRIVAGAGKPVIVIGDAPGKKAVPDLEKEGMGYLLIEADA
MIGARREFLDPAEMALFNANVIKVLAATGAFNVICEEVEKAIEGIKKGSPYLPRVVVTRQ
KAVEAAGFQNPYALAKAMAAYEMAKKVADLSVEGCFKMKEMKEYVPTVASSHEMMETAAR
LAGEARELEKATDSLLRRPHADDGKLLSKRKLMEKPG
>A0A523AY44|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Hadesarchaea archaeon|TrEMBL
MFSKVRIGVVKVGNIGTSTMIDLLLDERAEREDIDFRIVGSGPKMQEEDCKECAQKILEF
NPHLVLIVSPNPALPGPTAARRIVAGAGKPVIVIGDAPGKKAVPDLEKEGMGYLLIEADA
MIGARREFLDPAEMALFNANVIKVLAATGAFNVICEEVEKAIEGIKKGSPYLPRVVITRQ
KAVETAGFQNPYALAKAMAAYEMAKKVADLSVEGCFKMKEMKEYVPTVASSHEMMETAAR
LAGEARELEKATDSLLRRPHADDGKLLSKRKLMEKPG
>A0A089Z7S3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium formicicum|TrEMBL
MVVKIGVIKSGNIGTSPVLDLVLDERADRPNIDVRGVSSGAKMNPEQVEEVVPKIMDFEP
DFVIFISPNPGAPGPAKARELLSGMDVPALIIGDAPGMGKREEMDEQGLGYIVVLGDPMI
GARREFLDPTEMASFNADVIKVLAATGAYRVVQETIDGMIAACEAGNEIELPKVVIDAAK
ATDAAGFASPYAKAKAMAAYEMAAKVGDIDLKGCFMVKEMEKYVPIVASAHELIATAAKL
ATEAREIEKANDTVLRKPHGAQGQTLSKTVLVSKPE
>I1XGE3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methylophaga nitratireducenticrescens|TrEMBL
MKKILLHLDTDTVASTFDQAVAYDSGVDNIIAHGGATRDNVTAHVHGMIFTRGGKNLKNS
AIFIGGSNVTASELVGEAVKKAFFGPVRVSVMLDPNGSNTTAAAIARKVMTNYDITGKNV
VILGAGPVGQRTALYLLKEGASKVTLTCRSMARSKATVEHMKKAYGVDVIPGETRSDEAV
TALLKDAHVAIAAGPAGVCIVPEATWTASKTLEVIADVNAVPPLGVEGMEVMDNGTEKQG
VRFYGAIAIGNFKMKVHRGAVASLFDTNDLFLDETTIYDIACKIDNA
>A0A662R2K0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MVKIGFVKLGNLGISQGIELLLDEIAQREGVEVRVFGTGAKMSPSEAEASVELKKWGPDF
VVIVSPNASAPGPTKARELWKDVPTVVISDGPTKKDDRKALEEAGFGYIILPVDPLIGAK
REFLDATEMILFNSDAQKVLGNIGASRLVKQEIDKLIDQVNEGKKELELPHILATPEKCV
ERMNFSNPYAKAKAIAAGHIASKVAEINFKACFVLKDVADIALTAAAGHEALRVAAKLAD
EARELEKAGDTVYREPHAKSGELLKKVKLLEKPQ
>A0A368PCX0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|ANME-2 cluster archaeon|TrEMBL
MSDVKIGFVKLGNLGMSQVIDLILDEIAARQGIAVRTLGTGAKMGADEAADTVSLIKHWD
PDFVVMISPNAGAPGPTAAREIYKDTPTIIVSDGPDKKDARQALKEAGFGSIILKVDPLI
GAKREFLDPTEMASFNADAMKVLSVCGPVRLIQEEIDKVIDQVAAGKSGKDLELPYILGS
PDKCVERGCFENPYAKAKALAALHMANTVAAINFPACFMLKEVEKVSLVAAAGHEMMGAA
AVLAREAREIEKSNDTLFRNPHAKDGKQLAKTKLFDKPA
>A0A7J9T516|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|ANME-2 cluster archaeon|TrEMBL
DKKVIVISDGPTKKDDRKALEDAGFGYIIMKVDPLIGAKTEFLDPVEMASFNSDAMKVLS
TCGVVRLIQEAFDAVIAQADAGKDLELPHLLVSAQKAVESAGFNNPYAKAKALAALHMTD
KVAEINFPACFMMKDIEQVTLTTATGHEMMRAAAQLAIDAREIEKGNDAVFRQPHMKDGS
LKTKTKLYEKPQ
>A0A257ADZ2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon ex4484_138|TrEMBL
MVKVGFIKMGNIGTSIVIDLLFDEIAQREDSETRTFSSGAKMSKKEASQTEELKGWNPDL
VIMISPNAMAPGPVAAREIWKDVPTIVVADGPTKKEGRQKLEDAGFGYIVLTVDPLIGAK
REYLDTVEMVNFNADVTKTLAVTGAIRLVQETIDGVIEELKAGKTPTMPHILAKPEKCVE
YGGFANPYAKARWI
>A0A8J8JR35|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|ANME-1 cluster archaeon GoMg4|TrEMBL
MDVVKVGFVKLGNIGISRIADLLLDERADREDIEVRVLGTGAKMSPENAPDTARLLDWDP
DVVMVLSPNAALPGPTKAREMVKEKGKPCIVISDAPTLKAKDKLKEAGFGYIIIPGDPMI
GARREFLDPTEMSLFNVDVLSVLTITGVVKLVQEEIDRVIGEIKAGGEVKVPQIVATAEK
AVARAGFSNPYAKAKAIAAYSMAEKVAELDVKGCFMMKDPEAYVPMVAAAHELIAEAAKL
AKEAREIEKYTDSVLRMPHSRKGEILKKTKLAEKPSA
>A0A532TWG7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Hadesarchaea archaeon B3_Hades|TrEMBL
MVEKVRIGLVKLGNIGTSTMLDLMLDERAEREDIDFRVVASGPKITEEDCEGVSEKILDF
NPELIIAISPNPSLPGPSKAREILKKSGKPCVIIGDAPGAKIAGELEKAGFGFIFVEADS
MLGARREFLDPIEMSLFNADVIKVLSVTGAFRVIFEETDKAIEGTKSGKPYLPKVIVNRD
KAVGAAKFENPYARAKAMAAFEIAKKVSGVSAEGCFKVKEREKYIPIVAAAHEMMSAAAK
LCDEAREIEKSGDSVLRRPHGRMGELLSKKKLMEIEK
>A0A7J3M374|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus fulgidus|TrEMBL
MSKVKVGVLKMGAIGTAVILEYLLDERADREDIEVRVVTSGAKMQPEEAVVAEKLKEFNP
DLIIVASPNAALPGPKAAREAFAGKPVIVISDAPAKKAKDELKEKGFGYIFLNADSMIGA
RREFLDPTEMALFNADVLKVLAATGALRVVQEAIDKVIEDIKAGKKPELPQIVVTAEKAV
EAAKFSNPYAKAKAMAAYFIAEKVADINVRGCFVEKDYNVYVPLVASAHEMMRIAAMLAD
EAREIEKYGDKVFRNPHSRDGKILSKIELISKPQ
>A0A523WED9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKIGVFKCGNIASSPLFELLLDELADRKDIETRTVTTGSKMGVRDVEDALPKIFEFSPNL
LVFISPNPSIPGPAKVRERLSNKGIPSVVISDAPAKRIKKELEEQGLGYIIIMGDPLIGA
RREFLDPIEMAIFNSNIIKVLAIVGVYRIIHQEIDKLIHATKTGLNPVLPKLIIDVNIIR
DRPDFKNPYAKAKALAAYELTEKIAEINIQACFRESESNKYIPLVACAHEIAQIAAKLAE
EAREIEKYSDTLVRKPHSKSGKLKVKTKLMLPPTPDEEFYRNG
>A0A7J3V484|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKKVRVGIFKCGNIGTAPLLELLLDELADREDISVRTITTGAKMLAEEVAEALPKIFDFN
PDFIIFISPNPAVQGPRKAMEILLEKKVPSIFISDAPGKRLKEEFEKQGFGYIIVMGDPL
IGARREFLDPTEMAIFNSNVIKVLAITGVYKIIQQEIDRIIQCCKEGLTFELPRLIIDTD
TIRDNSDFRNPYALAKAMAAYELTKKIAEINTRACFMEKEREKYLPLVACAHEIAEVASY
LAEQAREIEKYSDTLVRRPHSKEGKLKVKERLMDSPIFEEAFR
>A0A7C4U1W2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
ALAKAMAAYELTKKIAEINTKACFMEKEREKYLPLVACAHEIAEVASYLAEQAREIEKYS
DTLIRRPHSKEGKLKVKERLMESPVFEEVFR
>A0A0F8VJB7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Lokiarchaeum sp. (strain GC14_75)|TrEMBL
IAAFELATSVSKLTGKACFQLKEKSDYMPLLAAAHEMMRTAAIMCDEAREIEKYNDTVIR
KPHNSKQQLLTKKGLYDKET
>A0A7K4A2Z9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVNNMVAWKP
DFAIVVSPNGVLPGPTGARERLAAAGIPTLFITDDVTTKKEWAEIKDGKFGYIIMKGDAM
IGARREFLDPIEMADYNGNLVKVLALTGAFRKLQNAIDQVIDQVKAGKKGADLAMPKLIV
TSDKAVDGEFSNPYALAKARAAYEIASAVAMVNVKGCFMTKEWEKYIPIVTSAHEMMRAA
AVLCDEAREIEKAGDGIIRKPHKKDGIIVSKTKLISKPE
>A0A7K4DGC8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMITFMATSGTKLQPEDIDRVVNNMKAWAP
DFCIVVSPNGVLPGPTQARENLAAAGIPCVVITDDITTKKEQFTALKESDFGYIIMKADA
MIGARREFLDPVEMADYNGNLVKVLALTGAYRKMQLELDKVIDQVKAGKKGKDLALPKVV
MTADKAVEGEFSNPYALAKARAAYEIAQQVAAVNVRGCFMVREWEKYIPIVASAHEMMRQ
AMVLCEEAREIEKAMDAVIRKPHKKTGEIVSKTQLISKPE
>A0A3B1C287|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|hydrothermal vent metagenome|TrEMBL
MRNHLFFLSTDSHASPFDMNIALDAGFDVALPYVCVKEEQVEGLTHDIIFSRGPKGTKHS
AIFVGGSDMELVEKIVKRAGDSMFDPFTVSIFSDPKGAYTTAAALVAKTGKAVGGLSGKK
IVIFGGTGPVGQVAAALCSKENADTTIVTSRDKKAGEEAAVRISSVYGVSIKGAAAKTGE
ERLALIQEADIAIATVKAGIQILSLNELGSVKNPLIVADVNAVPPSGFGGLAPGDDMKQI
APCVKGIGALCIGFIKYKVEVDIFESMLENKITANFKTAYESAKTLA
>A0A1V4UCE3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoregulaceae archaeon PtaB.Bin009|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVNNMVAWKP
DFAIVVSPNGVLPGPTGARERLLASGIPTVFITDDVTTKKEWAEIKDGKFGYIIMKGDAM
IGARREFLDPIEMADYNGNLVKVLSVTGAFRKLQMALDQVIDQVKAGKKGAEIALPKLVV
TSDKAVDGEFTNPYALAKARAAYEIASAVAMVNVKGCFMTKEWEKYIPIVCSAHEMMRVA
AVLCDEARELEKACDGVIRKPHKKDGVIVAKTKLISKPE
>A0A401HRK1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanofervidicoccus abyssi|TrEMBL
MVVKVGIIKCGNIGTSPLVDLILDERADRKDIDVRVLGSGAKMGVEQVEEVTKKMIEDIK
PDLIVFISPNPAAPGPKKARELLSKCGIPSVIIGDTPGLKVKDDIEKEGLGYIIVKCDPM
IGARREFLDPIEMVLFNADVLKVLAGTGAIRVVQNAIDSMINAIKEGKEVELPKIVVNES
KAVESMEYTNPYAKAKAMAAFKIAEMVGDTNVKGCFMVKEREKYLPVVASAHEMIRYAAK
LVDEAREIEKSLDTVSRKPHGADGRILNKKKLMEKPE
>A0A1Q6DUD9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Methanohalarchaeum thermophilum|TrEMBL
MNVGVAKFGNIGSSFIDLLLDERATRKNLEIKVAGSGSKLDKKSCLSALDSLLNFDLDLV
LIISPNPKLKGPKAARKKTKKQDIPVIVIGDVVDKDLKNELEENKFGYILLKNDPLIGAR
REFLDPIEMADFNSNILKILALSGVFRKIQSELDQVINQPQENKNKLPNIVIDEFNATKN
EFDNPYARYKAIGALKIAKSVDKTNLKGCYKYEDPDKYIPTVASTHEMLKAAKDLVEEAR
EIEKSNDTVKRTPHKKNGNIIEKRKIQK
>A0A7K4IE11|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thorarchaeota archaeon (strain OWC)|TrEMBL
MDERKVKVAVLKMGCIGAAPLLEYLLDERAQRKDIEVRAFSSGSKLLPEFCRESIDDALR
WSPDLAVLVSPNAALPGPTLARDRFHEANIAALTVGDGPSLKAFQKKDADGEKKTTAHPR
QGFVILPMDPMIGARKETLDATEMVLFNSDLLRVLSVTGVVRLLRRTIDGIVQSLAQGKE
PEMPKLHTTKEDCIKNAGFHNPYARAKAYAALQMTESVATLTTEACFREKEKERCTLLAT
AAHELLRAAARLADEAREVEKTNDALLKTSES
>A0A524G4A0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thorarchaeota archaeon (strain OWC)|TrEMBL
MPFKLAIVKMGCIGSSPLLDFIFDERAECENLEVRVFASGAKMDTNSCRTLIDYVREYKP
DLVLLASPNAGLEGPSLAREVLREIGVYVISISDAPSKKVWYAKDDGVKQAVHVFEKQGF
IIVPPDSMIGARAEFLDPTEMVLFNSDILRVLANGGVIRAIQSLVGKVISDISNAIQPDL
PKITLDAEVAIEYANYQNPYAKAKAYASLKIAESVSGVTSEACFKRKDSHEYIPLTASGH
ELMRAAAKLADEAREVEKTQDSVYRTPHGSDRRIKSKERLMDKPK
>A0A1Q9N705|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Odinarchaeota archaeon (strain LCB_4)|TrEMBL
MVKIAVLKMGNIGVSPLFEFLFDERAERVNVKFRVFGSGSKMTGESLDESIRDLVNWPHD
LTILITPNASLPHCMSVIEALRETGTPLIVLSDSPSLKVVEDLRSRNVGYIIITADPMIG
ARREFLDPTEMVIFNSDILKLLAGTGVMRFIVKIIDNVIEKLENGVAELPFIVIDSSFLL
ENPPFNNSYANAKALAAFKMAELVGKMNQEACFKIQEWARYTTLAAAAHEVLSAAAKLVD
ELRDMLKTSDTLLREPHDVNGRLLRKIKLLEKPE
>A0A662JME7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thermoprotei archaeon|TrEMBL
MQEPVRVGVIKLGCIGCAPLFEYLLDERADRGDITVRVVTSGAKMNPEEAEQLVKMLEPF
KPQLIVVLSPNAALPGPTKAREAAKALNVPVVVVSDAPAKKAVAKFEEGGFGYIIVEADS
MIGARREFLDPVEMALFNADVIRVLAITGVFNTLVKAVDEMIAAIKRGEEVKLPKIVVNK
DLAIENAGFSNPYAQAKAMAAFEAARRVADLTTEGCFKVQEWAKYIPLIAAGHELMRYAA
KLADEAREIEKSADQVMRMPHRASGELAVKRRLVEKLPKLK
>A0A497RHE1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Heimdallarchaeota archaeon|TrEMBL
MKKVGILKLGNIASSILLEMLLDERADREDIQVRTISSGAKLTETATNEAFELLSKEVFD
LVIIATPNASLKIPKQIIKKIHEKGQPVIVITDHLKKETKEEFVSEKIGFLVVKADAMIG
ARREFLDPIEMALYNSDLLKVLAIGGAFTILYSEINRALESIVKKNTENYLPQVVITAKK
AVKAADFFNPYAKAKARAALEIAEKVAKVNSEACFKLQERQQYLHQVATAHEMMQTAAKL
AGEAREIEKSINKVKRQPHHYKGQIQSKRLLMEKPDNPYKD
>A0A7J4MU31|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermobacter thermautotrophicus|TrEMBL
MVVKIGIIRCGNIGTSPVLDLLLDERADRPNIDVCVVGSGAKMNPDEIERAVPTMLEMDR
DFVIFISPNPGAPGPAKARELLSEADVPAMIIGDAPGLRVKDEIEEQGLGYIIVKADPMI
GARREFLDPTEMASFNSDVIKVLAFTGAYRVVQNTIDAMIADVEAGKAPELPQVVIDTDV
AVEAAGYENPYAKAKAMAAYEIATKVADIDVKGCFMVQDPDKYIPIVASAHEMLAAAAKL
AVEAREIEKANDTVLRTPHGKEGETLSKTDLLAKPE
>A0A0F8F0C3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina mazei|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMAPADAADTESFKQWNADF
VVIISPNAAAPGPTAAREIWKDAPCIIVSDGPTKKEAREAFEQEGFGYIILPVDPLIGAK
REFLDSVEMASFNADAMKVLSICGVVRLIQEELDKVTEQVASGKSGKDLELPHIFAKPEK
CVEHAGFANPYAKSKALAALHMAEKVAQVNFPACFMLKEIEQVCLTAAAGHEIMGAAAQL
ANQAREIEKSNDTVSRMPHAKNGAVLKKVRLYEKPE
>A0A133V157|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|candidate division MSBL1 archaeon SCGC-AAA261C02|TrEMBL
MQKVRVGLVKLGNIGTSPMLDLMLDERAEREDIEFRSVSSGPRMGKEDSKDVAEKILEFN
PDLITIISPNPTTPGPSSARDALSETGVPCTVVGDAPGTQITDDLEEAGFGYIFVIADSM
IGARKEFLDPTEMALFNADLIKVLSITGALRAVRQEMDKAIESIKSSELYLPRIIVDRDT
AAEAAGFENPYAKVKAMSAFEIASKVAELSVEGCFKVQDKEKYIPIVGSAHEMMRTAAQL
ADEARELEKSKDSVLRKPHADDGKTLSKRKFMETPK
>A0A822IV64|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MVVKVGFIKLGNLGTSQVIDLLLDEIAAREGIAVRVFGTGAKMGKEEAAETASFKNWGPN
FVVMISPNSSAPGPTAARDVWKDTPTIVVSDGPTKKEDREKLEQAGFGYMILPVDPLIGA
KREFLDCVEMATFNTDALKVLSICGAIRLVQTEIDKVIDQVAAGTKPLVLPKILAKPDKC
VESAGFNNPYAKAKALAALHIATKVAEIDFPACFVLKEADQVAIAAASGHEAMRAAARLA
DEAREMEKANDSVLRKPHAKDGRLLTKTKLLEKPQ
>A0A662RTJ9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MIKIGFVKLGNIATSRMVDLLLDERADREDIDVRVLGTGAKMTPEVAADTARLLDWDPDM
VVVISPNAALPGPKRARNMVRERGKPCIVISDGPAKKAVNELKENGFGYLIIPGDPMIGA
RREFLDPVEMSIFNSDALSVLSVTGVMRLLQEEIDRVIEALKAGKDKEVELPQMIVTAEK
AVERAKFSNPYAKAKAIAAYNMLERVAEMDARGCFVMKDPMDYIPMVAAAHELLREASKL
AFEAREMEKQADRLVREPHSRSGELREKEKLLEKPGA
>A0A7J4EMR1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MVVKIGFIKLGNLGTSQVVDLLLDEIAQREGIAVRTLGTGAKMGKDEASATKHLKEIWKP
DFVVMISPNASAPGPTAAREIYKDIPTIVISDGPTKKDARKALEEAGFGYIILPVDPLIG
AKREFLDPAEMVLFNSDAAKVLSVCGAIRLVQEEIDKVVAQVAEEEEIKLPHILAKPDKC
VERMDFSNPYAKAKALAALHLAEKVAEINFQACFVIKDAEKVALTAATGHEVMRVAAQLA
DEARELEKSNDTVLRKPHAKSGKLLSKVKLLEPPK
>A0A7J2H9S5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus veneficus|TrEMBL
MVKVGVLKMGAIGTALLVEYLLDERADREDIEVRVVT
>Q0W2P5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)|TrEMBL
MTVRVGIVKLGNIGTSRFIDLVLDERADRDIYVRTVGAGAKMGEAEAEEMKKIIDFKPQF
CIVISPNATVPGPTKAREMLKEAGIPTIVISDSPVLKIKDDLKAKGFGYFVVKCDPMIGA
RRQFLDPTEMVLFNADVLKVLANTGVVRLIQKELDAVIEGFAAGQTPALPQIVISADKAV
AAAGYKNPYAKAKAMAAFVAAEKVADIDLQGCFMQKEMEQYIPTVASAHELLREAAKLSD
EARELEKATDAILRTPHAADGKVLSKTQLMLKPE
>A0A1V4ZRF7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoregula sp. PtaU1.Bin006|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLEPADVDRVVSNLKAYKP
DFCIVVSPNGVLPGPTSAREELAKAGIPVVIITDDVTTKKEWEGVKASKFGYIIMKADSM
IGARREFLDPVEMADYNGNLVKVLALTGAFRKLEVALDKVIDQVKAGKKGDAIELPKIIM
TTDKAVEGEFTNPYALAKARAAHEIAMAVAGQNVKGCFMTKEWEKYIPIVASAHEMMRSA
AVLCDEARELEKAGDSIMRQAHKKDGTLVAKKKLVAKFD
>A0A1F5DSR6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon RBG_13_52_12|TrEMBL
MMVLIGFLKVGNIATAPMIELLLDERAEREDMEVRVVSSGANMGGRQSEEVARIMVGLKP
DLVFVTSPNASTKGPTKARELISASGIPVVVVSDGPRSLIEELQGKGMGCIIVEADSMIG
ARREFLDPIEMALFNADATKVLSVTGVYSLIYQTIDALIEKLKSSEKLELPSLNITREKA
LKVSGLSNPYSLAKAGASYEMAKRVSTLTTEACFKEKDWTIYTALCATAHELMRTAALVA
DNAREIEKYGDNVMRKPHYDDGSHLIKKRLIEKPEKQK
>A0A843HM94|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter sp|TrEMBL
YAKAKAIAAYEMAGAVAGLDMKGCFMTKGFENFIPLVAAAHEMAACAAALAAEAREIEKS
NDTVLRTPHMKEGNVGCKLDLISKPE
>A0A0F7DBG0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Geoglobus ahangari|TrEMBL
MVKVGVLKMGAIGTALLVEYLLDERADRGDIEVRVVTSGAKMQPEEAVVAEKLKEFDPDV
VIVISPNAALPGPKAAREAFEGKPVIVISDAPAKKAKDELAEKGFGYILINADSMIGARR
EFLDPTEMALFNADVVRVLAATGAFRIVQEEIDKVIEAVKKGETPELPKIVITAEKAVKA
GNFQNPYAKAKAMAAFYIAEKVADIDVKGCFIEKDPEKYIPLVASAHEMMRIAAQLADEA
REIEKSNDTVYRTPHSKDGEILKKFKLMEKPE
>A0A257MQ76|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosaeta sp. ASM2|TrEMBL
ISCMQMPSLFATWSGSGPASSSSKWKRKGRMFLAKSAWSLISITQVGNGIYPLADYLHTS
KSFYLLLGFTGGMFKIGLVKLGNIATSTVIDLALDEIAERSDIEFKIISFGPKMTKKEGE
ASEELKAWQPQLVVICSPNAATAGPTAARENFKGTPTIVISDGPAKKESRDALAAEGFGY
IILPMDPLIGAKREFLDPAEMALFNSDALRVLAAGGAIRLVQEELDRVMAGISAGEAKLP
VILATPEKCAERMHFSNPYARAKAVGSLYMAQTVAGIDAAACFRLKELEAIALTAAAGHE
VMRAAARLADEAREMEKAGDSISRHPHARTGELMNKTGLLDKPEKI
>A0A832P8T1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMGPADAADTESFKQWNADF
VVIISPNAAAPGPKAAREIWKDVPCIVVSDGPTKKEAREALEQEGFGYIILPVDPLIGAK
REFLDPVEMASFNADAMKVLSICGVVRLIQEELDNVTDQVASGKSGKALELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMADKVAQVNFPACFMLKEIEQVCLAAAAGHEIMGAAAQL
AIQAREIEKSNDTVFRQPHAKDGTLLKKVKLYQKPE
>A0A8E7EJ36|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanospirillum sp. J.3.6.1-F.2.7.3|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVTNMKAWGP
DFCIVVSPNGVLPGPKGAREALGAAGIPCVVITDDITTKKEEWEALKASEFGYIIMKGDS
MIGARREFLDPIEMADYNGNLIKVLSITGAFRKLQVALDEVIDQVKAGKKGKDLALPKIV
MSSDKAVEGEFSNPYAYAKARAAYEIAQAVAGVNVKGCFMTKGFENYTPIVASAHEMMRQ
ATLLCDEAREMEKATDAVIRKPHKNDGTRVAKKTLISKPE
>A0A0W8FFW0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|hydrocarbon metagenome|TrEMBL
MVIKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVSNMKAWGP
DFCIVVSPNGVLPGPTGAREQLAEAGIPVVVITDDITAKKEFAELKESKFGYIIMKGDAM
IGARREFLDPIEMADYNGNLVKVLSITGAFRKLQTELDKVIDQVKAGKKGADLALPKVVM
TSDKAVDGEFTNPYALAKARAAYEIAQAVAGVNVKGCFMTKEWEKYIPIVASAHEMMRQA
AALCDEARELEKAGDGVIRKPHKKDGVIVSKTKLISKPE
>A0A2Z5PUW2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcus maripaludis OS7|TrEMBL
MVVKIGILKCGNIGMSPVVDLCLDERADRNDIDVRVLGSGAKMGPEQVEEVAKKMVEEIK
PDFIVYIGPNPAAPGPKKAREILSAGGIPAVIIGDAPGIKDKDAMAEEGLGYVLIKCDPM
IGARRQFLDPVEMAMFNADVIRVLAGTGALRVVQNAIDDMVFAVEEGKEIPLPKIVITEQ
KAVEAMDFANPYAKAKAMAAFVMAEKVADIDVKGCFMTKEMEKYIPIVASAHEAIRYAAK
LVDEARELEKATDAVSRKPHAGAGQILNKCKLMEKPE
>A0A256ZGM6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Desulfurococcales archaeon ex4484_217_2|TrEMBL
MSQEEKVVKIGIIKPGAIGTSVILEYLLDERADRKDIDVRVYGTGSKMVVDEDLLNAAIQ
ANHDLYIVAAPANVKVIKKIAKKLKEAGKRVIIISDEPVKKSTKDFEEAGYGYIIVYGDP
MIGARREFLDPTEMALFNAYVLTVLSATGALRIVTKAIDSVIEALKEGKEPELPKIKLSK
KKLEKEAGFSNPYALAKAIAAYEMARKVAELTSEACFKEQEPERYITLAAAAHEMIRYAA
KLAEEARELEKPTDSLLRTPHHSSGKLLSKTKLLEKPR
>A0A842Y0I2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Methanoperedenaceae archaeon|TrEMBL
MVKVGFIKLGNLGTSQVIDLLLDEIAAREGIAVRVFGTGAKMGKDEAGSTKHFKEWKPDF
AVMISPNANAPGPTAARELWKDIPTIVVSDGPTKKDDRQKFEDAGFGYIILPVDPLIGAK
REFLDPVEMVSFNTDAAKVLAVCGAIRLVQEAIDNVIDQVASGNSPLELPKILGKPEKCV
ESAGFANPYAKAKALAALHIATKVAEIDFPACFVLKEVEQVVITAAAGHEAMRAAAKLAD
EAREIEKANDSVLRKPHAKAGHLLSKTKLLEKPQ
>A0A7C3Y635|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MTKVGFLKLGNIGSAPMIEFLLDERAEREGLKVRVVSSGAKLGVEEAVELAEAIDAFKPD
LAIVTSPNASLPGPLKAVETLSSRGYPTTVVSDSPAKKALEKFEALNAGYIIVEADSMIG
ARREFLDPAEMAVFNADVIKVLAVTGAFNAIRDVMDGMIRDVVEKRNPTLPKLIIDGEKA
VEAASFTNPYAKAKAFAAYETARKVSDLTVKACFQVKEWERYTVLAAAAHELMRKAASMA
DEAREIEKSNDQLCRTPHADDGTILRKRRLVEKPS
>A0A842YJJ8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
IKEGKKPVLPEIVITKGKALAASELKNPYAYGKAMAAFEMARGVADLTTEGVFKTEDRDE
IIQKVTAAHEMIRQAARLADDAREMEKANDSVVRITHFKSGERRKKTELFGKYEK
>A0A7J3QY45|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MAEEVAEALPKMFDFNPDFIIFISPNPAVQGPRKAMEILLEKKVPSIFISDAPGKRLKED
FEKQGFGYIIVMGDPLIGARREFLDPTEMAIFNSNVIKVLAITGVYKIIQQEIDRIIQCC
KEGLTFELPRLIIDTDTIRDNSDFRNPYALAKAMAAYELTKKIAEINTRACFMEKEREKY
LPLVACAHEIAEVASYLAEQAREIEKYSDTLVRRPHSKEGKLKVKERLMDSPIFEEAFR
>A0A832LY41|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MPVKIGFAKLGNIGAAPLLEFLLDERAEREDLSVRVVGSGAKMNVEEAAEIAEKLLEFKP
DLAIVVSPNASLPGPEKAREILSKAGIPVLVISDAPAKKAVKKLEEGSFGYLIIEGDPMI
GARREFLDPIEMALFNAEVIKVLAGSGAFNILFNEIDKVIEALKKGEKPQLPKKIIDSEA
AVEAAEFQNPYAKAKAQAAYEMAKKVAEMNVQACFVIKDWQKYTVLAAAAHELIREAAKL
IDEAREIEKNSDSVARHPHYDDGKILSKRRLIEKPR
>A0A2E8ED94|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVKITIVKTGYIATTTLIDALLDERASRKNISVRVISSGCKMNEGEAADIGNIAAQVPTD
LYVIISPNAGLPGPSRVREILKVTGKPIIIISDEPSRKIAKQLGEEEGIGYLVLYGDPMI
GAKRPFLDPIEMALFNADAIRVLSVTGVFRLIHSELDRVIDEIEHDKEPVLPMMIVNKTR
ALEHSGLRNPYARAKAMAAFEAARKVATLDVEGCFKIKGASNYLPIVAAAHELMRTAARL
CDQAREIEKANDSVERLVHFKDGTLKRKTKLLGKFE
>A0A523VU71|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKVKVGVFKCGNIGTAPMLELLLDELADRKDLAVRTVSTGSKMDVEAVEETIEKIFEFAP
DLLLFISPNTSAPGPAKAREIFSKKKVPTVIFTDGPGKRAKEEIETQGLGYVIIMGDPLI
GARKEFLDPLEMAIFNSNVIKVLACTGVFRRIFREIDRLIDALKSGSDLTLPRLIIDTDD
IRGAGDFKNPYAMVKAMAAYELLKKVAEINVRACFIEKDKEKYVPFVACAHEIVQTSANL
AEEAREIEKYGDTLLRTPHGKDGRLKTKNKLMLPPKASEQ
>A0A497KSL5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MSSQTVRVGILKLGCVGTAPLMEYLLDERADRTDIKVRIVSSGAKMDPEEAEEVTKEMLN
LKPNFVVVVSPNASLPGPAKAREILKEAGLPVIVVSDSPAKKVVKDLEAKGFGYIIVEAD
SMIGARREFLDPTEMACFNSDIIRVLAVTGVYNLLVRELDKVIQAFKEGKEPELPRFVVD
KTKAVEAADLQNPYAKAKAMAAYEAARRVGDLNVEGCFKLQEREAYIPVVATAHELMSYA
SKLAAEAREIEKYGDTLTRKPHAKDGTLLTKVKLLEKPEKK
>A0A3R7FAF7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MAVSPVKVGVLKLGCVGTAPLLEYLLDERADRGDIKVRVVSSGAKLDPEEAEDVAKGILQ
FKPNFAIVVSPNAALPGPTKAREILKEAGLPVLVVSDLPAKKAAKDMDAKGFGYFVVEAD
SMIGARREFLDPVEMACFNADIIKVLALTGVFNLLVKCVDGIIQAFKEGKQPELPKIVVD
KAKALKEAGYQNPYAYAKAMAAFEAARRVGDLTTEGCFKIQEREVYIPIVAAAHELMRYA
SKLAEEARETEKSEDMVLRKPHGKDGSLLSKVKLMEKPEKK
>A0A3R7YDA8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocalculus sp. MSAO_Arc1|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMESFMATSGTKMQTDDIDRVVSNMKAWGP
DFCVVVSPNGILPGPTSAREELAKAGIPVVVITDDITSKKEKFEGLKASNFGYIIMKADA
MIGARREFLDPVEMADFNGNLVKVLSLTGAFTKLQLALDEVIDQVKAGKKGADLVLPKLV
VTSDRAVDGEFVNPYALSKARAAHEIAQAVADVNVKGCFMTKEWEKYIPIVSSAHEMMRV
AAILCEEARELEKAGDSVIRKPHKKDGVRVSKTKLITKPE
>A0A1V4ULA5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoregulaceae archaeon PtaB.Bin108|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLEPADVDRVVSVLKAWKP
DYCIVVSPNGVLPGPTGAREQLAAAGIPTLFITDDVTTKKEWAEIKDGKFGYIIMKADAM
IGARREFLDPIEMADYNGNLVKVLAVTGAFRKLQTALDGVTDQIKAGKKGAEVVMPKLVI
TSDKAVEGEFTNPYAMAKARAAFEIASAVAMVNVKGCFMTKEWEKYIPIVSSAHEMMRVA
AALCDEARELEKSVDGVIRKPHKKDGVIVAKTKLISKPE
>A0A328P8W8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermobacter tenebrarum|TrEMBL
MVAKIGVLKCGNLGTSPVIDLVLDERADRPNVEIRVMGSGTKMNPDDIEFVVPKMLELDR
DFVIFISPNPGAPGPARARELLSEADVPAMIVGDAPGLRVKDEIEEQGLGYIIVKADSMI
GARREFLDPTEMAAFNADLMKVLALTGAYRVVHNTIDAMIADVEAGKEIELPQLVITRDV
AVEAADFKNPYAKAKAMAAYEIASKVADIDVEGCFMVQDPEKYIPIVASAHEMMSTAARL
AEEAREIEKSNDTVKRTPHGKEGETLSKEKLLEKPS
>A0A0A8K9M5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methyloceanibacter caenitepidi|TrEMBL
MKKLLFLFDTDPVPSIFDTVVGYDGGADNVTGYAAVTPDNVGALIDGCIYTRGGKDKQNT
AIFVGGGNMAKGEELFETVKKHFFGPFRVSVMLDSNGSNTTAAAGVALLAKGRDLKGKKA
VVLAGTGPVGMRAAGFFGMEGCDVTITSRTKERAEEAAKVIEKRFGIKVSGAAGATDEER
TEAVKDANIVYSAGAIGVQLLPKSAWENNPNIELLADVNAQPPMGVEGVDAMDKGKDLGG
GKLGYGALGIGGLKLKLHRECIAKMFQSSEGVYDAEEIYALAKEMA
>A0A0X3BMI1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoculleus bourgensis|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMITFMATSGTKLQPEDIDRVVSNMKAWAP
DFCIVVSPNGVLPGPTQAREDLAAAGIPCIVITDDVTTKKDQFAALKESDFGYIIMKADA
MIGARREFLDPIEMADYNGNLVKVLAITGAYRKMQLELDKVIDQVKAGKKGKDLVLPKVV
MTSDKAVDGEFSNPYALAKARAAYEIAQQVAAVNVKGCFMTKEWEKYIPIVASAHEMMRQ
AMILCEEARDLEKGMDAVIRKPHKKTGEIVSKTKLISKPE
>A0A6N1YEJ7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|methanotrophic endosymbiont of Bathymodiolus puteoserpentis|TrEMBL
MSKPLILHMLTTAKNLSPFDVNMAVDAGWVSAIPYTNVEPDEVQGLVQDAIFSRSPKGLK
FTGFFIGGRDTKQAMDMLKAATEAMFPPFQVSVFADPSGAFTTAAGMVAVVEDQLKTKFS
TDLAGKNTLILGGTGPVGQVAAVLAAQAGANVRIIGRQLDKAQRITDMCNQEFGAGKITI
TAGADADKAEYIKTADVVFATGAAGIELLSAELIASAPQLKVAADVNAVPPSGVAGLDPF
DNGKAIAGSQSGAVGVGALAIGNVKYQVQSKLLKTMIEKDHPLYLHFEHAFAAAREYIQA
SK
>A0A347AFG8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium sp. BRmetb2|TrEMBL
MVVKIGVIKCGNIGTSPVIDLLLDERADRPNIDTCVIGSGAKMNPEEIEKAVPLMLEMER
DFVIFISPNPGAPGPAKARELLSAADVPAIIIGDAPGLRAKDEMDEQGLGYIIVKADPMI
GARRELLDPTEMASFNSDVIKVLALTGAYRVVQNTIDAAVANVEAGSGVELPKVVISRDV
AIEAANFANPYAKAKAMAAYEIATTVANIDVEGCFMVQDAAKYIPIVASAHEMLGTAAKL
AMEAREIEKANDTVTRTPHGGDGSTVSKVALMDKPQ
>A0A662VZ80|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobales archaeon|TrEMBL
MVKVGVLKMGAIGTALLVEYLLDERADRGDITVRVVTSGAKMQPEEAEVAEKLKEFDPDF
VIVVSPNAALPGPKAAREAFEGKPVIIISDAPAKKAKDEFKEKGFGYILINADSMIGARR
EFLDPTEMALFNADVIKVLAATGAFRLVQEAIDGVIDALKEGKTPELPQVVVTAERAVAA
GNFKNPYARAKAMAAYYIAEKVADIDVKGCFIEKDPEKYIPLVASAHEMMRVAAIEADRA
REIEKGGDSVYRTPHSKDGAILKKYSLMEKPQ
>A0A5E4KWE6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon|TrEMBL
MVVKVGFIKLGNLGTSQVIDLLLDEIAAREGIAVRVFGTGAKMGKDEAAETASFKNWGPD
FVVMISPNSSAPGPTAARDIWKGTPAIVVSDGPTKKEDREKLEQAGFGYIILPVDPLIGA
KREFLDCVEMASFNSDALKVLSVCGAIRLVQTEIDKVIDQVAAGTKPLALPKVLAKPEKC
VESAGFANPYAKAKALAALHIATKVAEIDFPACFVLKEVDQIATTAAAGHEAMRAAAKLA
DEAREMEKANDSVLRKPHAKDGRLLSKTKLLEKPQ
>A0A1F5CT59|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon RBG_16_57_9|TrEMBL
MVTVTIVKVGYIGTTTLIDALLDERSARSDIKIRVISSSVQMGEEDAGDAARIAASVPSD
LYIAISPNVSLPGPTKVREVLKATGKPIIVIGDEPSRKAAKGLAEEGIGSIVIYGDPMIS
AKAPFLDPVEMALFNSDVLRVLAVTGVFRLVHTTLDRVIEEIKAGQKPQLPQLIINKTAA
LAASDIKNPYAYAKAMAAYEASKEVASLSTEAVFKIEDKNEAIPVLAAAHELMRMAAKLA
DEAREIEKGNDTAVRLAHFKKGDLRRRVRLFDEPEK
>A0A1V4ZY89|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoregula sp. PtaU1.Bin051|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVSNMKAWKP
DFCIVVSPNGVLPGPTGAREQLAAAGIPVIVITDDVTTKKEWEGIKNSKFGYIIMKADSM
IGARREFLDPVEMADYNGNLVKVLALTGAFRKLQEAVDKVIDQVKAGKKGDALELPKIVM
TTDKAVEGEFTNPYALAKARAAYEIAMAVAMVNVKGCFMTKEWEKYIPIVASAHEMMKIA
AKLCDEARELQKAGDVILRKAHKKDGVQVAKTKLVAKFD
>A0A7K3ZYP5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothrix sp|TrEMBL
MFKIGLVKLGNIATSTVIDLALDEIAERSDIEFKIISFGPKMTRKEGEASEELKAWAPEL
VVVCSPNAATPGPTAAREKFKGLPTIVISDGPAKKEACDALAAEGYGYIILPMDPLIGAK
REFLDPAEMALFNSDALKVLAACGAIRLVQEELDAAMIGIAAGEAKLPAILATPEKCAER
MHFSNPYARAKAVGALYMSQAVAGIDAAACFRLKELEAIALTAAAGHEVMRAAARLADEA
REMEKAGDSVSRHPHARTGELMNKTGLLDKPEKI
>H1KZN0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanotorris formicicus Mc-S-70|TrEMBL
MKKGDIMVVKIGILKCGNIGMSPIIDLCLDERADRKDIDVRVLGSGAKMDPTSVEEVATK
MVNEIKPDFIIYIGPNPAAPGPKKAREILSQSDIPAVIVGDAPGLRAKDEIEKEGLGYII
IKCDPMIGARRQFLDPVEMALFNADVIRVLAGTGALRIVQNAIDEMIESVKEGKEVPLPK
IVINEEKAVEAMEFTNPYAKAKAMAAFTIAEKVGDVDVKGCFMVKEMERYVPIVASAHEM
LRYAAMLVDEARELEKAMDAVSRKPHHPEGKVLGKKKLMEKPE
>A0A0E3KPX1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina thermophila (strain ATCC 43570 / DSM 1825 / OCM 12 / VKM B-1830 / TM-1)|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFSTGAKMSPAEAADTENFKQWNPDF
VVIISPNAAAPGPTAAREIWKDVPCIVVSDGPTKKEAREALEQEGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLIQEELDKVTDQVASGKSGKELELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
AMQAREIEKSNDTVFRQPHAKNGALLKKVKLYEKPQ
>A0A2P0QMK7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured bacterium|TrEMBL
MEKPFILHMLTSAKNLSPFDVNMAMDAGWVSAMSYTNIEASEVQGLVQDAIFSRSAKNLK
RTSIFIGGRDTKQAMDMLKIAKRSMIPPFEVSVFADPSGAFTTAAAMVAAVEFHLLTKFN
TTLEGKNILALAGTGPVGQAAAVIAAKAGANVRIIGRQLDKAQHTADLCNNEFGEGKTNI
QAGADADKAQYINDTDIVFATGAAGIELLSIELIASAPQLKVAADVNAVPPAGIAGISAM
DDGKLIEGSVNGAVGVGALAIGNVKYQTQNLLLKRMIQSDKPLYLHFEHAFEVAREYMKS
THDK
>A0A366MGB1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocorpusculum sp. MCE|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMMTFMATSGTKLQKEDVDRVVSNLKAWQP
DFAIVVSPNGVLEGPVGAREDLKAAGIPTIVITDDVTTKKEGWEALKASGFGYIIVKADA
MIGARREFLDPVEMADYNGNLVKVLALTGAFRKLQMELDKVIDQVKAGKKGAELELPKLV
LNSDNSTKGEFTNPYALAKARAAYEIAQAVAGVNVKGCFMTKEWTDYVPIVASAHEMMRA
AANLCDQARELEKGCDGIIRKPHKKTGEIVSKVALISKPE
>A0A7J4NTY6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MAKVGFIKLGNLGMSQVVDLILDEIAARKGIEVMSFGTGAKMGKEEAAKTKHFKEFEADF
YVMISPNSSAPGPTAAREIWKDKKVIVISDGPTKKDDRQALEDAGFGYIVMKVDPLIGAK
TEFLDPVEMASFNSDAMKVLSTCGVVRLIQEAFDAVIAQADAGKDLELPHLLVSAQKAVE
SAGFNNPYAKAKALAALHMTDKVAEINFPACFMMKDIEQVTLTTATGHEMMRAAAQLAID
AREIEKGNDSVFRKPHMKDGSQKTKTKLYEKPQ
>A0A811T8Y6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Argoarchaeum ethanivorans|TrEMBL
MVKVGFVKMGNIGTSLAIDLLFDEIAEREDINTRTFSSGAKMGKEEADDTKHFKRWYPDL
LIMVSPNPSAQGPAEARRIWKDVPTIIISDGPTKKDERQKLADAGFGYIILPVDPLIGAK
REYLDTVEMVNFNAEVNKTLAFTGAIRLVQETIDGVIEEIEAGETLNLPHILAKPEKCIE
YGGFSNSYAKAKALAALHILLKAAEINSKACFGMKGIEAITLTTAAGHEMVRTASMLADE
AREIEKCNDTVSRKPHARDGKILSKTRLYEKPE
>A0A7C6BUA6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium sp|TrEMBL
MVVKIGVIKCGNLGTSPVIDLVLDERADRPNIDVRGVGSGAKMNPEQIEEAVPKIKDFDP
DFVVFISPNPGAPGPARARELLSEFDIPAVIVGDAPGMGKREEMDEQGLGYMIVLGDPMI
GARREFLDPTEMASFNADVIKVLAATGAYRVVQETLDGMIAACEAGSDVELPKVVIDAAK
ATEAGGFTNPYAKAKAMAAYEIAAKVGDVDLKGCFMVKEMEKYVPIVASAHEMIAAAAKL
AVEAREIEKANDTVLRKPHGGEGQTLSKTELVSKPQ
>A0A850LSD9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Helarchaeota archaeon|TrEMBL
MVKIGVIKCGNIGISPVLDLLFDEIAEREDITFRVVGSGPKLTPEHCEEATKLMLDIKPD
LIMFTSPNTSLPGPKKSRDMIQTAGIPAIYFSDHPGKKAKEVKEEIAGRGMGYFIIKPDS
MIGAKRPFLDPVEMCLYNSDVLRVLAICGVVNLIVDIVDKVIDQLKAGSKPELPQIVINR
NKALKAARFSNQYAKCKASAALDAAERVSGISVEGCFMVKGRENYLPVVGSAHELMRMAA
KLADEAREIEKANDSVLRRPHAKDGKLLEKREFLAKPV
>A0A3R7F4X6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|ANME-2 cluster archaeon|TrEMBL
MTDVKIGFVKLGNLGMSQVIDLILDEIAAREGIMVRTLGTGAKMSPDEAKDTEALIKHWD
PDFVVMISPNAGAPGPTAAREIYKNTPTIVISDGPDKKDARQALKDAGFGSIILKVDPLI
GAKREFLDPTEMASFNSDAMKVLSTCGVVRMIQEELDKVVDQVASGKSGKDLELPYILAT
PEKCVERGCFENPYAKAKALAALHMANTVAAINFPACFIHKDVEKVTLTAAAGHELMNAA
ACLAREAREIEKSNDTVFRQPHAKAGNLLTKTKLYDKPA
>A0A843F134|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter sp|TrEMBL
MVVKIAIIKSGNIGTSPVIDLLLDERADRPNIDVRTFGSGAKMNPEQVEDVVPKIDAFEP
DFAIFISPNPGAPGPAKARELLSEKDVPAIIIGDAPGKGKKDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNADILKVLAETGALRLVQKTIDGVIEQAEAGEIELPKLIITAEKA
VEAAEFANPYAKAKAIAAYEMAGAVANLDMKGCFMTKGFENFIPLVAAAHEMAACAAKLA
QEAREIEKSNDTVLRTPHMKEGNLGCKTDLISKPE
>A0A843ER99|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter sp|TrEMBL
AAAHEMAACAAKLAQEAREIEKSNDTVLRTPHMKEGNLGCKTDLISKPE
>A0A2I0PXV9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacteriales archaeon HGW-Methanobacteriales-2|TrEMBL
VIFISPNPGAPGPAKARELLSGMDVPALIIGDAPGMGKREEMDEQELGYIVVLGDPMIGA
RREFLDPTEMASFNADVIKVLAATGAYRVVQETIDGMIAAAEAGEAIELPKVVIDAAKAT
ETAGFASPYAKAKAMAAYEMAAKVGDIDLKGCFMVKEMEKYVPIVASAHELIATAAKLAT
EAREIEKANDTVLRKPHGPQGQTLSKTVLVSKPE
>A0A847PQF4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMGPDDAADTESFKQWNADF
VVIISPNAAAPGPKAAREIWKDVPCIVVSDGPTKKEAREALEQEGFGYIILPVDPLIGAK
REFLDPVEMASFNADAMKVLSVCGVVRLIQEELDKVTDQVASGKSGKELELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMADKVAQVNFPACFMLKEIEQVCLTAAAGHEIMGAAAKL
AIEAREIEKSNDTVFRQPHAKSGALLKKVKLYQKPE
>A0A7J4KAW7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoregulaceae archaeon|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVNNMVAWKP
DFAIVVSPNGVLPGPTGARERLLAAGIPTLFITDDVTTKKEWAEIKDGKFGYIIMKGDAM
IGARREFLDPIEMADYNGNLVKVLALTGAFRKLQMAVDQVIDQVKAGKKGAELVMPKLVV
SSDKAVEGEFTNAYALAKARAAYEIASAVAMVNVKGCFMTKEWEKYIPIVTSAHEMMRVA
A
>A0A1D2W7S3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosphaera sp. A6|TrEMBL
MVVKIGIVKVGNIGTSVLIDMILDERADREDIDVRTISSGAKMGKNQMDDVLPKIDEYNP
DVIIFISPDPGAKSPSSARETLSKKNIPTIVIGDGPGERAIGSMKEQGLGYIIVKADSMI
GARREFLDATEMAVFNSDVLMVLSTTGVFRLIHKTLDKVIRDIDEDKLYSLPELVITAEN
AVDAADFKNPYAKSKAIAAYSIACQVSSMNVRACFKTKDYHVYIPLVSAAHEMMSAASKL
AYEAREIEKSNDTVVRTAHRRNGSILYGTSLNDNKE
>A0A0E3SPW6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina barkeri 3|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMSPAEAAASESFKQWNADF
VIIISPNAAAPGPTAAREIWKDVPCIVVSDGPTKKEARETLEKDGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLIQEELDKVTDQVAAGKSGKDLELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
ATQAREIEKSNDTVFRQPHAKNGTLLKKVKLYQKPE
>A0A0E3NUC0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp. MTP4|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVCGTGAKMGPDDAAYTESFKQWDADF
VIIISPNAAAPGPTAARELWKDKPCIVVSDGPTKKDARQALEDEGFGYIILPVDPLIGAK
REFLDPVEMASFNADAMKVLSLCGVVRLIQEEFDKVADQVNAGNSGKELELPHIFAKPEK
CVEHGGFANPYAKAKALAALHMAEKVAQVNFPACFMLKDIEQVCLATATGHEIMGAAAVL
ATQAREIEKSNDTVLRQPHAKNGTLLTKTKLYEKPQ
>K2R351|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium formicicum (strain DSM 3637 / PP1)|TrEMBL
MVVKIGVIKSGNIGTSPVLDLVLDERADRPNIDVRGVSSGAKMNPEQVEEIVPKIADFDP
DFVIFISPNPGAPGPAKARELLSGMDVPALIIGDAPGMGKREEMDEQGLGYVVVLGDPMI
GARREFLDPTEMASFNADVIKVLAATGAYRVVQETIDGMIAACEAGEDIELPKVVIDAAK
ATEAAGFASPYAKAKAMAAYEMAAKVGDIDLKGCFMVKDMEQYVPIVASAHELIATAAKL
ATEAREIEKANDTVLRKPHGAQGQTMSKTVLVSKPE
>A0A7J9PHS4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcus maripaludis|TrEMBL
MVVKIGILKCGNIGMSPVVDLCLDERADRNDIDVRVLGSGAKMGPEQVEEVAKKMVEEVK
PDFIVYIGPNPAAPGPKKAREILSAGGIPTVIIGDAPGIKDKDAMAEEGLGYVLIKCDPM
IGARRQFLDPVEMAMFNADVIRVLAGTGALRVVQNAIDDMVFAVEEGKEIPLPKIVITEQ
KAVDAMDFANPYAKAKAMAAFVMAEKVADIDVKGCFMTKEMEKYIPIVASAHEAIRYAAK
LVDEARELEKATDAVSRKPHAGEGKILNKCKLMAKPE
>A0A0G3CI83|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina barkeri CM1|TrEMBL
MVNIGFIKMGNLGMSQVINLVQDEIAAREGITVRVFGTGAKMSPAEAAASESFKQWDADF
VIIISPNAAAPGPKAAREVWKDVPCIVVSDGPTKKEAREALEKAGFGYMILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLVQEELDKVTDQVASGKSGKELELPHIFAKPEK
CVEYAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAASQL
AIQAREIEKSNDTVFRQPHAKNGTLLKKVKLYQKPE
>A0A3G9D315|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermobacter sp. MT-2|TrEMBL
MVAKIGVLKCGNLGTSPVIDLVLDERADRPNVEIRVMGSGTKMNPDDIEFVVPKMLELDR
DFVIFISPNPGAPGPARARELLSEADVPAMIVGDSPGLRVKDEIEEQGLGYIIVKADSMI
GARREFLDPTEMAAFNADLMKVLALTGAYRVVHDTLDAMIAEVEAGKEVTLPQVVITRDV
AVEAAGFQNPYAKAKAMAAYEIATKVADIDVEGCFMVQDPEKYIPIVASAHEMMSTAARL
AEEAREIEKSNDTVKRTPHGKEGETLSKAKLLEKPS
>A0A662SVF5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Korarchaeota archaeon|TrEMBL
MEPVRVGFGKLGNIATSLIVELLLDERAERKDIDVRVVSSGAKLGEAEAEEVARRLMEFS
PRLAVVSSPNAALKGPTLLRRMLKEAGIPVIVVSDEPAKRAIKSMEEEGFGYIIVEADSM
IGARREFLDPAEMALYNAYVLTVLACTGALNAVFKSIDRVIEQVKQGAELELPRLVVNAE
RALSEAGFQNPYALAKARAAYEAARKVAELTVRGCFIEKDWTKYTVLVAAAHELMRLAAR
MAEEAREIEKYSDSVMRVPHHSKGHMLVKRRLIEKPAKVEGG
>A0A662SF94|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Korarchaeota archaeon|TrEMBL
MVRVGFVKLGNIGCAPLIEFLLDERAEREDISVRVIGCGAKMNPEDAEEISKKMLEFNPD
FVVITSPNASLPGPTKAREILAQSVPVIVVSDLPAKKIVSELEEKGIGYIIVEADAMLGA
RREFLDPIEMALFNADLIKVLSITGVYNILFESIDKVIEAIKEGKKPELPKIVVKAKKAI
KAAGFSNPYAASKAMASFEIAKNVADVTVTACFKEKDWEKYTLLCSAAHEMMAEAAKLAS
EAREIEKSADRVLRKPHYDDGTILIKRALIEKPSKPE
>A0A7J3LZX2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKEVVTVGFGKLGCIASSPLIEYLLDERADRDDLVVRVVSSGAKMGEKDAEDVAKALIEF
KPDLAVAVSPNAGLPGPRRLRSLLKDANIPTIIVSDAPSRRIVKELDEGGYGYIIVLGDS
MIGARREFLDPVEMAIYNADLIKILSATGAFRVIQIELDRVIEYLKKGEELKLPKIVVDR
KVAVEAGQFTNPYAKAKAIAAYEAAAKVADLTVEGCFKIEDWVEYTSIVAAAHELMSYAA
KQASEAREIEKGLDTVYRSPHNRKGEILSKRKLIEKPSKPG
>A0A7C5TBZ3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKKVKVGVFKCGNIGTAPLLELLLDELADREDISVRTVTTGAKMLAEEVLEALPKIFDFK
PDFIIFISPNPAVEGPRKAMDILLERRIPSIFISDAPGKRLKEEFEKRGFGYIIVMGDPI
IGARREFLDPTEMAIFNSNVIKVLAITGVYKIIYQEIDRIIHCYKEETKLELPKLIIDTD
NIRDRSDFRNPYALAKAMAAYELTKKIAEINTRACFVEKER
>A0A7J3I3Y0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MEVVKVCVVKAGNIGSAPLLELLLDERADRSDIDVRVISSGAKLNPEQAEEIAEKVFDFK
PDLVLVVSPNAALPGPSKIREVMAKAGVPTISITDAPGKRAREDIEGKNQGYII
>A0A7J2U900|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
FEKAGFGYIIIMGDPLIGARKEFLDPLEMAIFNANVIKVLAITGVFRIIHQEIDKIIYSI
KEELIPQLPRLVIDTDTIRDRSDFRNPYARAKAMAAYELTKKVAEINTKACFIEKEKEKY
IPLVVCAHEIAQVAAKLAEEAREIEKYSDTLVRKPHSKDGRLKVKEKLMMPLVFDETIY
>A0A3N5WMW9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Euryarchaeota archaeon|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVTNMKAWKP
DFAIVVSPNGVLPGPTGAREALLAAGIPVVVITDDITTKKEQWEALKASKFGYIIMKADA
MIGARREFLDPIEMADYNANLVKVLALTGAFRKLQMALDKVIDQVKAGKKGEQLELPKIV
MTPEKAIDGEFSNPYALAKARAAYEIASAVAGVNVKGCFMTKEYVDYVPIVTSAHEMMRM
AAALCDQARELEKGMDAVIRKPHKKDGTIVSKTKLISKPE
>A0A522V8V4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Methanoperedens sp|TrEMBL
MVVKVGFIKLGNLGTSQVIDLTLDEIAAREGIAVRVFGTGAKMGKDEAAETASFKGWKPD
FVVIISPNSSAPGPTAARDIWKDTPTIVVSDGPTKKEDREKLEQAGFGYIILPVDPLIGA
KREFLDPVEMVSFNSDAAKILSVCGPIRLVQTEIDKVIDQVAAGTKPLALPKILGKPEKC
VESAGFANPYAKAKALAALHIATKVAEIDFPACFVLKEVDQIATAAAAGHEAMRAAARLA
DEAREIEKANDSVFRKPHAKDGRLLTKTKLLDKPQ
>A0A2Z5PG47|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcus maripaludis KA1|TrEMBL
MVVKIGILKCGNIGMSPVVDLCLDERADRNDIDVRVLGSGAKMGPEQVEEVAKKMVEEIK
PDFIVYIGPNPAAPGPKKAREILSAGGIPAVIIGDAPGIKDKDAMAEEGLGYVLIKCDPM
IGARRQFLDPVEMAMFNADVIRVLAGTGALRVVQNAIDDMVFAVEEGKEIPLPKIVITEQ
KAVEAMDFANPYAKAKAMAAFVMAEKVADIDVKGCFMTKEMEKYIPIVASAHETIRYAAK
LVDEARELEKATDAVSRKPHAGAGKILNKCKLMEKPE
>A0A2V3JEN2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanophagales archaeon|TrEMBL
MVKVGFVKLGNIGASRIVDLLLDERADREDVDVRVLGTGAKMTPDCAADASRLLDWDPDL
VVVVSPNAALPGPKRAREMAKEKGKPCIVISDAPAKKAVPKLKEGGFGYIIIPGDPMIGA
RREFLDPVEMSLFNADVLSVLSITGVAKLLQEEIDAVVEAVKSGASGPSGASGEEVKLPQ
IIATAEKSVERAGFSNPYAKAKALAAYSMTEKVAELDVKGCFMMQKPEEYVPVVAAAHEL
LREAAKLAFEAREMEKQTDSLVREPHARSGEIMRKVGLLEKPSA
>A0A0F8T115|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp. 1.H.T.1A.1|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVCGTGAKMGPADAADTESFKQWNADF
VVIISPNAAAPGPTAARELWKDVPCIVVSDGPTKKEAREAFEQDGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLIQEELDRVTEQVASGKSGKELELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
ATQAREIEKSNDTVFRQPHAKSGALLKKVKLYEKPQ
>D7EB48|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanohalobium evestigatum (strain ATCC BAA-1072 / DSM 3721 / NBRC 107634 / OCM 161 / Z-7303)|TrEMBL
MVKVGFIKLGNLGMSQVVDLLEDEIAAREGITTRVYGTGPKMSKEDAADTEAFKEEFDPD
FVIIISPNASTPGPTEARQLWKDKPCLIISDGPTKKDDRQAIEDEGFGYIILPVDPLIGA
KTEFLDPEEMASFNSDVMKVLSTCGAVRLVQEELDKLTSQVDEGKSGDEIEMPHIYAKPQ
TCIERSGFSNPYAKAKALAALHMAEKVSQINLPACFMLKDLEEVAFTAATGHEMIRAAAE
LAVEAREIEKTNDTVLRKPHSKKGKVLSKTKLYEKPQ
>A0A662G5E5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thermoprotei archaeon|TrEMBL
MSAERPVRIGVVKTGNIGSSVLLDILLDERAERGDIIVRVVGSGPKLTPEEVKEVVEKLL
EFKPDLVLMASPNAALPGPAEGRELLAKTGVPTIVLTDGPGKKAVKDIEAKGMGYIIVPA
DSMRGARREFLDPTEMAIYNADLIKVLACTGVYHAIVRAVDKAIEGLKAGRQPELPRLVL
GRDEAVQAARFTNPYAHAKAMAAYEMAAKVADLTVEGCFKVREWEQYTHIVAAAHELMRE
AARLADEAREIEKYGDTVFRAPHNKKGVLLEKIKLIEKPKKPEEG
>A0A5E4KBD0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon|TrEMBL
MVVKVGFIKLGNLGTSQVIDLLLDEIAAREGIAVRVFGTGAKMGKDEAQETASFKNWGPD
FVVMISPNSSAPGPTAARDVWKGTPVIVVSDGPTKKEDREKLEQAGFGYIILPVDPLIGA
KREFLDPVEMASFNSDALKVLSIGGAIRLVQTEIDKVIDQVAAGTKPPALPKILAKPEKC
VESAGFSNPYAKAKALAALHIATKVAEIDFPACFVLKEVDQIATAAAAGHEAMRAAARLA
DEAREMEKANDSILRKPHAKDGRLLTKTKLLEKPQ
>A0A2P0QL43|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon|TrEMBL
IIMKADSMIGARREFLDPVEMADYNGNLVKVLALTGAFRKMQLALDKVIDQVKAGKKGDA
IELPKVVMTVDKAVDGEFTNPYALAKARAAYEIASAVAMVNVKGCFMTKEWEKYIPIVAS
AHEMMKVAAQLCDQARELEKAGDSIFRQPHKKDGVLVNKKKLVAKFE
>A0A1D2WM20|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter sp. A27|TrEMBL
MVVKIAIIKSGNIGTSPVIDLLLDERADRPNIDVRTFGSGAKMNPEQVEDVVPKIDAFEP
DFAIFISPNPGAPGPAKAREMLSEKDIPAIIVGDAPGKGKKDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNSDILKVLAETGALRLVQQTIDTVIEQAEAGEIELPKLIVTAEKA
AEAGGFANPYAKAKAIAAYEMAGSVANLDMKGCFMTKGFENFIPLVAAAHEIAACAAKLA
QEAREIEKANDTVLRTPHMKEGNLGSKTDLISKPE
>A0A842PKA4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobia archaeon|TrEMBL
MEVVKIGFVKLGNIGTSRIVDLLLDERADREDIDVRVLGTGAKMTPENAADTARLLDWDP
DVVVIISPNAALPGPKRAREMVKEKGKPCIVISDAPAKKAVDKLKEGGFGYIIIPGDPMI
GARREFLDPVEMSLFNADVLSVLSITGVAKLVQEEIDGVIEAIKKGGEVKLPQIMATAEK
SVERARFSNPYAKAKAIAAYNMVECVADMDVKGCFMMKNPEEYVPMVAAAHELLREAAKL
AFDAREMEKQSDRLVREPHSRTGAIMKKVKLMEKPSA
>A0A524FLN3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thorarchaeota archaeon (strain OWC)|TrEMBL
MSDLHQIGILKIGAIGAAPLLDLLLDERAERKDIAMCVVTTGASMDPKQSEEATKVLAGA
NPSLVMIVSPNASLPGPTKAREILLGKKIPILTISDGPSKKAFYKKNEEGKSEKSVPAGS
GFIILPMDPMIGARKEFLDPTEMAIFNAELIKVLSCTGVLRLLQSEIDKLIESVKAGKEL
KLPTINAKIEDVLEHAGFANPYAYSKAYAALKMSETVADITSTACFKESDPAVYVPAVAA
AHELLRAAARLADEAREIEKQSDTVLRTPHGSSGKVQKKTKLNEKPT
>A0A256Y2Y4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobales archaeon ex4484_92|TrEMBL
MVVKVGVLKMGAIGTALLLEYLLDERADREDIEVRVVTSGAKMQPDEAKVAEKLKEFNPD
LIIVISPNAALPGPKAAREAFEGKPVIVISDAPAKKAKDEFKEKGFGYILINADSMIGAR
REFLDPTEMALFNADVVKVLAATGAFRLVQEAVDNVIDQLKAGQKPDLPQIIVTAERAVE
AGKFSNPYAKAKAMAAFYIAEKVADIDVKGCFIEKDPQKYIPLVTSAHEMMRIAAMLADE
AREIEKGNDTVYRTPHGRDGKVLSKVELMVKPE
>A0A7J9S0U0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcus maripaludis|TrEMBL
MVVKIGILKCGNIGMSPVVDLCLDERADRNDIDVRVLGSGAKMGPEQVEEVAKKMVEEIK
PDFIVYIGPNPAAPGPKKAREILSAGGIPAVIIGDAPGIKDKDAMAEEGLGYVLIKCDPM
IGARRQFLDPVEMAMFNADVIRVLAGTGALRVVQNAIDDMVFAVEEGKEIPLPKIVITEQ
KAVEAMDFANPYAKAKAMAAFVMAEKVADIDVKGCFMTKEMEKYIPIVASAHETIRYAAK
LVDEARELEKATDAVSRKPHAGAGKILNKCKLMEKPE
>A0A7C1AUM7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Syntrophoarchaeum butanivorans|TrEMBL
MVKVGFIKLGNIGMSLIVNLLLDERADREDIDVRVAGTGAKMGKPEAEDVLSFLKWEPEL
LIVTSPNAALPGPKIVREAFEGKPCIVISDGPAKKAVDEMKEKGFGYIILPGDPMIGARR
EFLDPTEMALFNTDVLKVLSVSGAARLVQEEIDRVIGEIKAGGKVTLPQIIATAEVVTQR
AQFSNPYARAKAIAAYSMAEKVAELDAKACFAMKDPEAYTLMVAAAHEIMREAARLADEA
RELEKAQDAVSRAPHGRSGEILSKRGLMEPLK
>A0A2A5NZG9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Geothermarchaeota archaeon ex4572_27|TrEMBL
MGAKEKAEVVRVGVVKLGCVGTAPLLEYLLDERADRNDVDVRIVSCGAKMDPEKAEEVAR
KLLDFKPHFAIVVSPNAALPGPTRAREVLKEAGLPVIVVSDAPAKKALGDLESKGFGAII
VEADAMLGARREFLDPVEMACFNSDIIKVLATTGVYNLLVEYLDKVISAFKEGRAPELPR
VVVDKEAAIAATGYTNPYARAKAMAAYETARKVADLTTEACFKIQEWERYTMVAAAAHEM
MRDAARLADEAREIEKYGDTLPRRPHARDGTLMSKTKLMEKPAKKA
>A0A257MIZ1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosaeta sp. ASO1|TrEMBL
MFKIGLVKLGNIATSTVIDLALDEIAERSDIEFKIISFGPKMTKKEGEASEELKAWQPQL
VVICSPNAATAGPTAAREKFKGTPTIVISDGPAKKESRDALAAEGFGYIILPMDPLIGAK
REFLDPAEMALFNSDALRVLAAGGAIRLVQEELDRVMAGISAGEANLPVILATPEKCAER
MHFSNPYARAKAVGSLYMAQTVAGIDAAACFRLKELEAIALTAAAGHEVMRAAARLADEA
REMEKAGDSISRHPHARTGELMNKTGLLDKPEKI
>A0A0E3PUE4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina mazei WWM610|TrEMBL
MKKMVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMAPADAADTESFKQWN
ADFVVIISPNAAAPGPTAAREIWKDVPCIIVSDGPTKKEAREAFEQEGFGYIILPVDPLI
GAKREFLDSVEMASFNADAMKVLSICGVVRLIQEELDKVTEQVASGKSGKDLELPHIFAK
PEKCVEHAGFANPYAKSKALAALHMAEKVAQVNFPACFMLKEIEQVCLTAAAGHEIMGAA
AQLANQAREIEKSNDTVSRMPHAKNGAVLKKVRLYEKPE
>R7PWY6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter smithii CAG:186|TrEMBL
MVVKIGIIKSGNIGTSPVLDLLLDERADRPNIDVRVFGSGAKMNPEQVEDVVPKVDQFDP
DFCIFISPNPGAPGPAKARELLSEKDIPAIIIGDAPGKGKKDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNADILKVLAETGALRLVQNTIDGVIDGAAAGNIELPKLIITAEKA
VEAAGFENPYAKAKAIASYEMAGAVANLDMKGCFMTKGFENFIPLVAAAHEMAASAAALA
DEAREIEKGNDSVLRTPHMKEGNTGRKTDLISKPE
>A0A0U3E6I8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter millerae|TrEMBL
MVVKIAIIKSGNIGTSPVIDLLLDERADRPNIDVRVFGSGAKMNPEQVEDVVPKIDAFEP
DFAIFISPNPGAPGPAKARELLSEKDLPAIIIGDAPGKGKKDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNADILKVLAETGALRLVQKTIDGVIAAADAGEEIELPKLIITAEK
AVEAAEFANPYAKAKAIAAYEMAGSVANLDMKGCFMTKGFENFIPLVAAAHEIAAAAAKL
AQEARELEKSNDTVLRTPHMKEGNPGRKTDLISKPE
>A0A135VUY1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Thorarchaeota archaeon SMTZ1-83|TrEMBL
MSDDVFKLGVVKFGAIGAAPLLDLIFDERADRKDLEVRVFTSGAKLDEDSCVDATRMVID
YKPQLVLSVSPNAALKGPAKSREMLHEAGLPTITISDGPSEKGFYKKGEDKKKVKTVLDK
QGFFILYADAMIGARREFLDPTEMVLFNSDIIRVLTNTGVMRLLQEEIYAVIESIKEGKE
PKMPTVKVTAEKAIAAGGFSNPYAAAKAYAALKISEAVADVTTKGCFVEQDPAKYIPLVA
AGHEMMRIAAVLSDEARELEKASDTLLRTPHTSKGKLKKKTALADDLK
>Q12XF4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)|TrEMBL
MAKIGFIKLGNLGMSQVIDLVQDEIAAREGISVRVFGTGPKMGKDEAAETAALKEWDADF
YVMISPNSSAPGPTAAREIYKDVPCIVISDGPTKKDDRQALEDAGFGYIIMTVDPLIGAK
REFLDSVEMASFNSDAMKVLSTCGVVRLIQEELDIVTAQVDEGKEIVLPHILAKPEKCIE
RAGFSNPYAKAKALAALHMADKVAQINFPACFMMKEIEQVTLTTATAHEMMRAAAQLAID
AREIEKSNDTVLRQPHAKKGNILSKTALYEKQQ
>A0A2I0NPF9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon HGW-Methanomicrobiales-6|TrEMBL
DAMIGARREFLDPIEMADYNGNLVKVLALTGAFRKMQTELDKVIDQVKAGKKGADLALPK
VVMTSDKAVDGEFSNPYALAKARAAYEIAQAVAGVNVKGCFMTKEWEKYIPIVASAHEMM
RQAMVLCEEARDLEKGMDAVIRKPHKKTGEIVAKTALISKPE
>A0A832WN25|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanopyrus kandleri|TrEMBL
MTVAKAIFIKCGNLGTSMMMDMLLDERADREDVEFRVVGTSVKMDPECVEAAVEMALDIA
EDFEPDFIVYGGPNPAAPGPSKAREMLADSEYPAVIIGDAPGLKVKDEMEEQGLGYILVK
PDAMLGARREFLDPVEMAIYNADLMKVLAATGVFRVVQEAFDELIEKAKEDEISENDLPK
LVIDRNTLLEREEFENPYAMVKAMAALEIAENVADVSVEGCFVEQDKERYVPIVASAHEM
MRKAAELADEARELEKSNDAVLRTPHAPDGKVLSKRKFMEDPE
>A0A523AKD4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobi archaeon|TrEMBL
MTKVKVGVLKMGAIGTAVILEYLLDERADREDIEVRVVTSGAKMQPEEAVVAEKLKEFNP
DLIIVASPNAALPGPKAAREAFAGKPVIVISDAPAKKAKDELKEKGFGYILINADSMIGA
RREFLDPTEMALFNSDVLKVLAATGTLRVVQEAIDKVIEDIKAGKKPELPQIIVTAEKAV
EAARFTNPYAKAKAMAAYFIAEKVADINVRGCFVEKDYNVYVPLVASAHEMMRIAAILAD
EAREIEKYGDKLFRNPHSREGKILSKIELISKPQ
>A0A133VB21|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|candidate division MSBL1 archaeon SCGC-AAA261G05|TrEMBL
MQKVRVGLVKLGNIGTSPMLDLMLDERAEREDIEFRSVSSGPRMGKEDSKDVAEKILEFN
PDLITIISPNPTTPGPSSARDALSETGVPCTVVGDAPGTQITDDLEEAGFGYIFVIADSM
IGARKEFLDPTEMALFNADLIKVLSITGALRAVRQEMDKAIESIKSSELYLPRIIVDRDT
AAEAAGFENPYAKVKAMSAFEIASKVAELSVEGCFKVQDKEKYIPIVGSAHEMMRTAAQL
ADEARELEKSKDSVLRKPHADDGKTLSKRKFMETPK
>A0A662JJN3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thermoprotei archaeon|TrEMBL
MSGKETVVKVGIVKLGCVGTAPMLEFLLDERADRKDIDVRVVSSGAKMDPDKAEEVAKKL
LDFKPHFAIVVSPNAALPGPTKAREILKEAGLPVIVISDAPAKKAMGDLESKGFGAIIVE
ADAMIGARRESLDPVEMACFNADIIKVLAATGVYNIVVDYVDRVIAAFKEGKTPELPRVV
VDKETANAATGYSNPYAKAKAMAAFETARRVADLTTEACFKIQEWERYTPIAAAAHEMLR
NAAKLADEAREIEKYSDTLQRAPHAKDGSPMVKSKLMEKPVKK
>A0A328S223|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosphaera sp. rholeuAM6|TrEMBL
MVIKIGIIKIGNLGTSTIIDLILDERADREDIDVRTISSGSKMEKEQVEDIMPRISEYNP
DLIIFISPNPNSKQPGVIRNYLSKTGIPTIVVGDQPGEKAINKMKEQKLGYILIRADAMI
GARREFLDPTEMALFNADVLKVLSITGTLRLVNHKIDEVINSIKEEEPIELPELVVTAEL
AVFNAGFKNPYAMGKAIAAYNMATLVSEMNITACFKIDEPDMYIPIVTASHELMLAAAKL
ADEAREIEKSNDTVLRTSHAKDGSVWVRQSLIDTYK
>A0A523TE91|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Heimdallarchaeota archaeon|TrEMBL
MVKDKSAKKDILKKNLGILKLGNIASSVLLEMLLDERADRLDIEVRTISSGAKLQKESIN
DAFGIFSKLTFDLVVVATPNASLSAPLEIINKLNETKIPLIVLTDILKKETREEFKEKNI
GYLVVKSDAMIGARREFLDPTEMAIFNADLIKVLSIGGALAAVQQEIDKTLNLIVSKKEI
VLPQIVLTPAKIVKYIGFSNPYAEAKARGALEIAEKVAKINTDGCFKINERSEYILQVAT
GHEMMQIAAKLAEDAREIEKSLNKVRRQPHSYYGEVQDKRLLKEKPGSNYDKRDV
>A0A497PHR3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thorarchaeota archaeon (strain OWC)|TrEMBL
MAGSAVKIAVVKLGCIGTLPLLDIMIDERADRKDVEIRAFSSGSKMDTTSCEDVTRTVLA
YRPDLVLLVSPNATLSGPTKARNALLSASIPTIAITDGPGQKAFMVKDEQGKKRPIQVEG
LGFIVIPQDPMIGARREFLDPTEMVLF
>A0A7C4NE40|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MSQQAPVKVGIIKLGCIGCAPLLEYLLDERADRNDISVRVVSSGAKMTPQEAEEVVKMLE
PFKPQLIIIASPNAALPGPTRAREVAKLLNVPTLIISDAPARKAVSKFEEGGFGYIIVEA
DSMIGARREFLDPTEMALFNADIIRVLAITGVFNLIVKTIDDMIASIKKGEEVKLPRLIV
TKEIALENAGFSNPYAYVKAMAAFEAARKVSDLTTEGCFKVQEWEKYIPLVAAGHELMRY
AAKLSDEAREIEKGLDQVMRMPHRASGELSVKRKLIEKLPPKA
>A0A523ZKF6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MDQVKIVVFKCGNIATSPLFELLLDELADRQDIRIRTVTTGSKMSVEDVEEALPKIFEFN
PNLIVSISPNPSISGPAKVREKLSSSDVPSVVISDAPAKRIKTKLEEQGLGYIIITGDPL
IGARREFLDPIEMAIFNSNIIKVLAITGVYRIVHQEIDKLIHAIKKGASPALPKLIIDAN
AIRDCSDFENPYAKAKALAAYELAEKIAEINFQACFVEKESEKYIPLVASAHEIAQTAAK
LAEEAREIEKYNDTLVRKPHSKKGNLKIKTKLMLPPTSDEEFHRKSLKK
>A0A497PSS9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thorarchaeota archaeon (strain OWC)|TrEMBL
MSDSFRLGILKLGCIGAAPLLDLILDERAERKDLDVRVVTTGASMDPAACEEVTAALAEM
HPGLVLIVSPNASLPGPSKAREILLEKNIPILSISDGPSKKAFYTKDEKGKRVVSVPDGS
GFIVLPMDPMIGARKEFLDPTETAIFNAELIKVLSCTGVVRFLQTQIDGLIEGLKAGETP
KLPTVTVSTKKALAHAEFSNPYAYAKAYAALKMAESVADITSRACFKEKDPEVYVPAVAA
GHELLRAAARLADEARELEKENDSVLRTPHDSSGKKLKKTKLHEKPA
>A0A7L4Q8H7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MFKIGFVKLGNIATSTAIDLSLDEIAERTDIEFKIISFGPKMTEKEGKGAEELKAWQPQL
VVISSPNAATAGPTAAREAYRGIPTIIISDGPSKKEAREALSAEGYGYIILPMDPLIGAK
REFLDPAEMALFNSDALRVLAACGAIRLVEEELDRSIASIISGQAKLPTILATPEKCAER
MHFSNPYAQAKAMGALYMAQTVATIDAAACFRLKELKPIALTAAAGHEVMRAAARLADEA
RELEKSNDTVSRQPHARTGELMQKLSLLDKPEKI
>A0A662RXJ6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MAEEVVKVGFVKLGNIGASRIVDLVLDERADREDVDVLSIETGAKLTPEHADATTAVVDW
NPDFVVVVSPNAALPGPKKAREIVASKGIPCIVISDAPAKKAVKSLKENGFGYILILGDP
MIGARREFLDAVEMSMFNANILAVLTATGVVRILHEELDSVISQIKRRKAGESVELKLPQ
IEITAEYAVERAGFSNPYAKAKALAAYAMAEKVADLDVQGCFVVKDPDKYVLLIAAAHEM
LETAAKLAMEAR
>A0A520KP98|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanonatronarchaeia archaeon|TrEMBL
MVVGIGKFGLIGSSFIDALLDERADRQDLDVRVVGSGAKMGERDCVSVVSSLLEFDPTHL
VLVSPNPGMPGPSKAREVVKKAGVPAVVVSDYLGIDSRDDVESDGFGYIYVKGDPLIGAR
REFLDSVEMADFNSNVLKVLSICGSFRKLQAEIDSFLGSDSEDPVLPKLVITPEKAVEGE
FENPYAASKAIGALEIANKVAELNHKVCFKLKDRERYVELASAAHEMLGKAASLAEEARE
IEKANDTVKRTPHAVDGEVKEKRRLFE
>A0A2E5KGP5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thaumarchaeota archaeon|TrEMBL
MTVNITVVKTGFLGVTTLIEALLDERASRKDISVRSVTSGSKMSSTEAQEVEQISNSLDT
DLYLVVSPNASLDAPKNLALNLGKTKPTILISDSPASKIKDELVDKIGYVFVQGDPLIGI
HKEFLDPIEMSNFNSDILKVLSITGAFQALINEIDQVIEQIKNSQSITLPKLIIGKHTAV
SNSGLTNPYSQAKALASYEIARLVARLSAEGAYKEKDRERRLLTVSAAHELIRQAAKLAD
EAREIEKQTDSVHRNIHDSSGKTVTKKKFFDSI
>A0A062V4F2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Methanoperedens nitroreducens|TrEMBL
MVVKIGFVKLGNLGTSLVIDLLLDEIAAREGIAVRVFGTGAKMGKDDAADTASFMSWKPD
FVIITSPNASAPGPTGAREIWRDIPTIIVSDGPTKKDDREKLEQAGFGYIILPVDPLIGA
KREFLDPVEMASFNSDALKVLSVCGAIRLVQAELDTVVDQVAVGAERPLTLPHILAKPER
CVESAGFSNPYAKAKALAALHIATKVADIDFQACFVLKELEQIAVAAAAGHEAMRTAARL
ADEAREIEKSNDSVLRKPHAKDGRLLSKTKLLEKPQ
>A0A2I0P870|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon HGW-Methanomicrobiales-2|TrEMBL
MVVKVGIAKLGNIASGVMGELLLDERADREDIITFMATSGTKLQPEDIDRVVSNMKAWGP
DFCIVVSPNGVLPGPVKAREDLAAAGIPCVVITDDVTTKKEQFEALKASNFGYIIMKADA
MIGARREFLDPIEMADYNGNLVKVLALTGAFRKMQMELDKVIDQVKAGKKGADLALPKVV
MTSDKAVEGEFSNPYALAKARAAYEIAQAVAGVNVKGCFMTKEWEKYIPIVASAHEMMRQ
AMFLCEEARTLDKGMDAVIRKPHKKTGEIVSKTTLISKPE
>A0A842M3U6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacteriaceae archaeon|TrEMBL
MVAKIGVLKCGNLGTSPVIDLVLDERADRPNVEIRVMGSGTKMNPDDIEFVVPKMLELDR
DFVIFISPNPGAPGPARARELLSEADVPAMIVGDAPGLRVKDEIEEQGLGYIIVKADSMI
GARREFLDPTEMAAFNADLMKVLALTGAYRVVHNTIDAMIADVEAGKEIELPQLVITRDV
AVEAADFKNPYAKAKAMAAYEIASKVADIDVEGCFMVQDPEKYIPIVASAHEMMSTAARL
AEEAREIEKSNDTVKRTPHGKEGETLSKEKLLEKPS
>A0A842KRE5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacteriaceae archaeon|TrEMBL
MVAKIGVLKCGNLGTSPVIDLVLDERADRPNVEIRVMGSGTKMNPDDIEFVVPKMLELDR
DFVIFISPNPGAPGPARARELLSEADVPAMIVGDAPGLRVKDEIEEQGLGYIIVKADSMI
GARREFLDPTEMAAFNADLMKVLALTGAYRVVHNTIDAMIADVEAGKEIELPQLVITRDV
AVEAADFQNPYAKAKAMAAYEIASKVADIDVEGCFMVQDPEKYIPIVASAHEMMSTAARL
AEEAREIEKSNDTVRRTPHGKEGETLSKRKLLEKPS
>A0A843ERL2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter sp|TrEMBL
MVVKIAIIKSGNIGTSPVIDLLLDERADRPNIDVRTFGSGAKMNPEQVEDVVPKIDAFEP
DFAIFISPNPGAPGPAKARELLSEKDVPAIIIGDAPGKGKKDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNADILKVLAETGALRLVQKTIDGVIEQAEAGDIELPKLIITAEKA
VEAAEFANPYAKAKAIAAYEMAGSVANLDMKGCFMTKGYENFIPLVAAAHEIAACAAKLA
QEARDIEKANDTVLRTPHMKEGNPGCKTDLISKPE
>A0A832RYE1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methermicoccus shengliensis|TrEMBL
MAKVGFVKLGNLGTSQGIDLLLDEIAQREGIEVRVLGSGAKMTPKEAEESAELKQWGPDF
VIIISPNAMAPGPTKAREIWSDTPTIVISDGPTKKDDRKAIEEAGFGYIIIPMDPLIGAK
RQFLDATEMISFNSDVLKVLSLTGVSRLVKEELDKVIAQVDAGKSGKELELPHILVTPEK
CTERMNFSNPYARAKAMAAAHIASKVPDLTFKACFVYKDIEDIVLAAAAGHEMMRIAAKL
AEESREIEKTLDEVSRMPHAKSGETLSKMKLYEKPQ
>A0A0W8ESN4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|hydrocarbon metagenome|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVNNMVAWKP
DFAIVVSPNGVLPGPTGARERLLAAGIPTLFITDDVTTKKEWAEIKDGKFGYIIMKGDAM
IGARREFLDPIEMADYNGNLVKVLALTGAFRKLQMAVDQVIDQVKAGKKGAELVMPKLVV
SSDKAVEGEFTNAYALAKARAAYEIASAVAMVNVKGCFMTKEWEKYIPIVTSAHEMMRVA
AVLCDEARELEKAGDGIIRKPHKKDGVIVSKTKLVSKPE
>A0A135VH54|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Thorarchaeota archaeon SMTZ1-45|TrEMBL
MSETTINVGVIKLGAIASAPLLDLIFDERAERDDINVRAFTSGAKMDEESSIGPAESLIA
WAPHLVLIVSPNAALPGPTKVREMLAEAKLPTISISDGPAEKAFYKKDDEGKKQPYVLDG
QGFIVIPADSMIGAKKEFLDPTEMSLFNADAIKVLSITGVVRAIQHELDIVIAAIQAGET
PKMPLVKLTAEEIVKCGYFKNPYAKAKAIAALTISEAVAEVTTKGCFKTKEAEDYIPLVA
AGHEMMRAAAKLADEIRELEKAGDSVLRNPHVSKGKVKTKTALMDKPK
>A0A024H1D4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Pseudarthrobacter siccitolerans|TrEMBL
MQIGVFSVSDITTDPTTGRTPTENERIKASVAIAKKVEEIGMDVYAIGEHHNRPFFSSSP
TTTLAYIAAQTERIILSTATTLITTNDPVKIAEDFAMLQHLADGRVDLVLGRGNTAPVYP
WFGKNIQDGVELAIENYSLLRKLWDEDTVNWSGKFRTPLQNFTSTPRPLDGVAPFVWHGS
IRTPQIAEVAAYFGDGFFANNIFWPKEHYQQLISLYRERYEHYGHGKADQAIVGLGGQFF
MRKNSQDAVKEFRPYFDNAPVYGHGPSLEDFTSQTPLTVGSPQEVIEKTLTFREYFGDYQ
RQLFLIDHAGLPLKTVLEQLDLFGEEVLPVLRKEYAALKPAHVPEPPTHANRVAAALAAQ
EQPAKDAEKSAVQA
>A0A1V4TGY8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium sp. PtaB.Bin024|TrEMBL
MVVKIGVIKSGNIGTSPVLDLVLDERADRPNIDVRGVGSGAKMNPEQVEEVVPKIMDFEP
DFVIFISPNPGAPGPAKARELLSGMDVPALIIGDAPGMGKREEMDEQELGYIVVLGDPMI
GARREFLDPTEMASFNADVIKVLAATGAYRVVQETIDGMIAAVEAGEEIELPKVVIDAAK
ATEAAGFASPYAKAKALAAYEMAAKVGDIDLKGCFMVKEMEKYVPIVASAHELIAAAAKL
ATEAREIEKANDTVLRKPHGAQGQTLSKTVLISKPE
>A0A0E3Q058|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina vacuolata Z-761|TrEMBL
MVNIGFIKMGNLGMSQVINLLQDEIAAREGITVRVFGTGAKMSPAEAAASESFKQWDADF
VIIISPNAAAPGPKAAREIWKDVPCIVVSDGPTKKEAREALEKEGFGYMILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLVQEELDKVTDQVASGKSGKELELPHIFAKPEK
CVEYAGFENPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
AIQAREIEKSNDTVLRQPHAKNGTLLKKVKLYQKPE
>A0A315Y3X6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Methanoperedenaceae archaeon|TrEMBL
MVVKVGFIKLGNLGTSQVIDLLLDEIAAREGIAVRVFGTGAKMGKDEAAETASFKNWGPD
FVVMISPNSSAPGPTAARDVWKGTPTIVVSDGPTKKEDREKLEQAGFGYMILPVDPLIGA
KREFLDCVEMATFNTDALKVLSICGAIRLVQTEIDKVIDQIAAGTKPPVLPKILAKPEKC
VESAGFANPYAKAKALAALHIATKVAEIDFPACFVLKEADQVATTAAAGHEAMRAAARLA
DEAREMEKANDSVLRKPHAKDGRILNKTKLLEKPQ
>A0A256Z3S2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon ex4484_231|TrEMBL
MPKNVKIGVLKLGCVGTLPLLDVLLDERADRTDIDVRVVGSGSKLGPQQCKEATELMINL
KPDIAVLVGPAQAAPGPTEARKMLKAAGLPVIVISDSPAKKLIKDIDEADQGYIIVEADS
MIGARREFLDPVEMAIYNSDVIRVLAITGVFNIVVETIDEVIQSLKAGKTPELPKIVING
EKAVEAGGFSNPYAKAKAMAAYEMACQVSKLTTRACFKVSDREVYVPLVTAAHEMMRTAA
RLADEAREIEKTGDTVSRKPHFKDGTLGTKKTLMEKPKRIK
>A0A7C7VN85|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Korarchaeota archaeon|TrEMBL
MVVKVGFVKLGNIGCAPLIEFLLDERAEREDIEVRVIGSGSKMNAEGAEEISKKILEFDP
DFVVITSPNAALPGPTKAREILAQKVPVIVVSDLPAKKIVPELEEKGIGYIIVEADAMLG
ARREFLDPIEMALFNADLIKVLSITGVYNILFESIDKVIEAIKRGEKPELPKIVVKGKKA
VKAAGFFNPYAASKALASFEIAKNVADVTVTACFKEKDWEKYTLLCSTAHEMMTQAAKLA
EEAREIEKYADKVLRKPHYDDGTILFKRALIEKPSKIN
>A0A842QWD1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVTVTFVKIGYIGTTTLIEALLDERSSRTDLTMRVISSGVKMDVPEAETVSKMAAAIDSD
LYVVITPNAALKGPKKAREVLKSTGKPVIAISDEPSRKSLKKVPEEGMGYIVIYGDPMIG
ATTAFLDPVEMAIFNSDVLKVLSVTGIFRLIQQELDRVIDEIKEGKKPTLPELVITKKKA
LAASDIQNPYAYGKAMAAFEMSRKVASLTTEALYKTKDRDETIHKVTAAHELIREAAKLA
DEAREIEKANDSVVRIAHYKSGERRRKTELFGKYEK
>A0A7J2YMU6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKIGAIKCGNIGTAPLLELFLDELADREDISVRSVTTGAKMVTEEVEDALSRIFDFNPHF
LIFISPNPAVQGPTRAREILLEKKIPSIFISDAPGKRLKEEFEKQGFGYIIILGDPLIGA
RKEFLDPTEMAIFNSNVIKVLAITGVYKMLYQEIDRIIHGYKAGLIPELPKLVIDTENIR
DQSDFKNPYAKAKAMAAYELTKKVAEVNARACFVEKEKEKYIPFVACAHEIAQIAATLAE
QAREIEKYADTLVRRPHSKEGKPKVKDKLMLPPTFDEEVYQKWLKSTK
>A0A497NJH7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MSQTINVGILKAGCIGTLPLLEFLLDERADRRDISVTVIGSGAKLGVEECREKAEIMVKV
KPDLVILAGPAQAAPGPTEARNILRSSGIPTIVISDSPAKKLRKTLEKEGFGYIIVEADS
MIGARREFLDPTEMAIYNSDVIRVLAVTGALRVIVEEIDRVIEALKRGEEPALPRLVIDK
NTIMERRGFSNPYSKAKAIAAYEISRRVADINTEACFKVSEWEVYTELVAAGHEMMRVAA
RLVDEAREIEKMNDSVLRTPHFGDGSRGEKSSLIEKPRRGG
>A0A497LKM4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVVKLGFIKLGNVGVAPLLELALDERAEREDLDVRVFGSGAKLTPEQAEDLAERLIAYKP
DLAVSVSPNAALPGPKKVREKLKEAGIPLITVTDAPGKKAVKDIEEKGFGYIIVKGDAMI
GARKEFLDPVEMLIFNADIIKVLAVTGVFNIFQEAFAKAIDAIKKGEKPELPRIIVTAEN
AVKAAGFSNPYAQVKAMAAYEILQKVAEMNVEGCFKIQERDQYVPVVAAAHEALRAAVIL
ANEAREIEKSMDTVLRKPHDKEGRILVKRKLFEKPSAQ
>A0A497FEF4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Verstraetearchaeota archaeon|TrEMBL
MNQLRIAVVKFGCIGSSPLIEIALDERANREDILVRVFSTGGKMDAENCIDVADAAVKFN
PQLIVNVTPNAALEGPRKGRMHLKDKLPNIPIIVISDEPAKKAEKDLKENGFGYIIIQAD
PMIGARRDFLDATEMVLFNSDILKVLAVTGVIRMLIAEIDKVISAIKSGGEVKLPQIIAD
AYFVVENYGGFSNPYAKAKAIASYEAARRVARLSTTGCYVLKDREAYMPMVAAAHELLRI
AAKLADEAREIEKSNDTVYRTPHVKSGEKRYKVKFMEKAHR
>A0A7J4E602|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVVKVGFVKLGNIGSAPLLEFLLDERAERKDIEVRVMGSGAKLGVPEASEVAERMLEYKP
DLAVVVSPNAALPGPTKAREVLSGAGIPVIVVSDGPAKKIIKKLEEGGFGYLIVEGDPMI
GARREFLDPAEMALFNADVIKVLAGSGALNALFFEIDKALDSLKRGERPQLPRLVVDGEK
AAEAAEFRNPYAKAKARAAYEMTKKAADMDVEACFVIKEWQKYTGLAAAAHELVREAARL
IDEARETEKGGDSVARHPHYDDGKILSKRRLIEKPK
>A0A497N0A7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MEVYGMVVKIGFVKLGNIGVAPLLELALDERAEREDIDVRVFGSGAKLTPEQAEDLAEKL
VAYKPDLAVIVSPNAALPGPKKVREKLHEAGIPAISVTDAPGKKAVKDIEEKGFGYIIVE
GDAMIGARKEFL
>A0A3M1RG57|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Euryarchaeota archaeon|TrEMBL
MLLVVAKTGNIGSSLVLDLLLDERADRKDIDVRVVSSGAKMSPAEADYVSKRVLELGPDL
VLYATPNASAPGPRKVIEALRGRRAIVVSDGPAVKAKDFIEERGLGYILVKADAMIGARR
EFLDPTEMAVFNADILKVLAGTGVVRLMQVEIGKTLSGLKEGKVYLPRIIVSAEKAVEHA
EYQDQKARENAMKAYKMAEEVGKLNVRGCFIEKDPDVYIRTVAEAHERLRQAAALVEEAR
LIEQQKDTLLRTPHSPDGRILRKTRLLEKPS
>A0A7K3YHU8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon|TrEMBL
DIDRVVSNMKAWGPDFCIVVSPNGVLPGPVKAREDLAAAGIPCVVITDDVTSKKEQFEAL
KASNFGYIIMKADAMIGARREFLDPIEMADYNGNLVKVLSVTGAFRKMQQELDKVIDQVK
AGNKGADIALPKVVMTSEKDVDGELSNPYALAKARAAYEIAQSVAGVNVKGSFMTKEWEK
YIPIVSSAHEMMRQAMHLCEEARELEKGMDAVIRKPHKKTGEIVSKTKLISKPE
>A0A8J7U8K7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Brockarchaeota archaeon|TrEMBL
MQEPVRIGFVKLGNIGTAPIVEFLLDERAERGDVSTRTVGAGSKIGTVEAEEVATKLLDF
KPQAAIVLSPNAALPGPTKARQVLAEAGVPTIVVSDGPTKKVLKQLEDGGFGYIVVEGDA
MIGARREFLDPVEMAIFNSDIIKVLSVTGALKAVTDEIDKVIDALKKGERPVLPRLVLDK
ERATEAAGFSNPYARAKAIAAYEVSCRVAAMTTEACFLVKDWERYTALAAAAHEAMRVAS
VLADEAREIEKACDSLLRSPHHDDGAVLSKRKLIEKPRRSEQPKGDVL
>A0A4Y3G1C3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|archaeon|TrEMBL
MLKLLIIKIGNIATSLVLELLLDERADRKDIEVDVATTGAKMTPDDAKRVLARVNLDEYN
LIIYISPNPAITGPEMIINALKGKNAIVIGDAPGVKIIKKLEEAQLGYLFILGDSMIGAR
REFLDATEMAIFNAEILKVLSITGALRLVQEEIDKAVDALKKGEKYLPRLVVDTAEAVEA
AGFENPYAKAKAMAAYEAIKLIGKLNIKGCFMVKDAREYIPLVTSAHELLRMAGIYSDEA
REMEKTMDTLLRKPHSMAGELLKKRLLMEKPS
>A0A833DQG2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermococcus okinawensis|TrEMBL
MVIKIGIINCGNIGTSPLIDLILDERADRKDIDVRVLGSGAKMGVEQVEEVTKKMIEDIK
PDLIIYIGPNPAAPGPKKARELLSNCDIPGVIIGDAPGLRVKDEIAKEGLGYIIIKCDPM
IGARREFLDPTEMALFNSDVLKVLAGTGALRVVQNAIDSIIDALKEGKEVQLPNIVINET
KALEAMEYNNPYAKAKAMAAFKIAEMVGDINVKGCFMVKEMEKYIPIVASAHEMIRYAAK
LVDEAREMEKSQDTVSRKPHASDGRILCKNKLIEKPQ
>A0A842TJD3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MTFKLGVIKCGNIGCSPILELLFDERADRENIDAIVIGSGAKLNPEQCENVTKLMVQQKP
DLIFITSPNASLPGPSNARKILQDSGIPSIIVTDAPGKEAIEDCEAKGIGYFIVKADSMI
GARRPFLDPIEMTIFNSQILSILALTGVFKLIINETEKVIKQISSGATPELPKIVINKKN
AIEAAGYANPYARNKAMAAHEICKSVASINVEGCFRTKGRENYMPIVGAGHEILTAALNL
AEEAREIEKSNNSVLREPHAPDGDLLTKRKFVSKGEKK
>A0A524DEN9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
EMNPELILMSSPNAALGGPKACREKAKEAGIPTIIISDSPAKKAVDEIKEKGMGYILVNC
DSMIGARRPFLDPIEMSIFNADLLKVLAITGALKVIAEELNKVILDMLEGRNPTLPQIII
DSSIATEAAGFSNPYAKAKAIAAFELAASVSKVTAKACFVLKERAEYMPLLAAAHEMMST
AALMCFEAREIEKANDTVLRKPHHAKQQFLTKRGLMDKEQ
>U6EAV6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium sp. MB1|TrEMBL
MVVKIGVIKSGNIGTSPVLDLVLDERADRPNIDVRGVGSGAKMNPEQVEEVVPKIMDFDP
DFVIFISPNPGAPGPAKARELLSEMDIPALIIGDAPGMGKREEMDEQGLGYIVVLGDPMI
GARREFLDPTEMASFNADVIKVLAATGAYRVVQETIDEMIAACEAGKDIELPKVVIDAAT
ATEAAGFANPYAKAKAMAAYEMAAKVGDIDLKGCFMVKDMEKYIPIVASAHELIAAAAQL
ATEAREIEKANDTVLRKPHGSKGQTMSKTVLVSKPE
>A0A843JZ08|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothrix sp|TrEMBL
MFKIGFVKLGNIATSTAIDLSLDEIAERTDIEFKIISFGPKMTEKEGKGAEELKAWQPQL
VVISSPNAATAGPTAAREAYRGIPTIIISDGPSKKEAREALSAEGYGYIILPMDPLIGAK
REFLDPAEMALFNSDALRVLAACGAIRLVEEELDRTIASIISGQAKLPTILATPEKCAER
MHFSNPYAQAKAMGALYMAQTVASIDAAACFRLKELKPIALTAAAGHEVMRAAARLADEA
RELEKSNDTVSRQPHARTGELMQKLSLLDKPEKI
>A0A832C8Z2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus sp|TrEMBL
MAKVKVGVLKMGAIGTAVILEYLLDERADREDIEVRVVTSGAKMQPEEAVIAEKLKEFDP
DLIIVASPNAALQGPKVAREAFAGKPVIVISDAPAKKAKDELKEKGFGYIFLNADSMIGA
RREFLDPTEMALFNADVLKVLAATGALRVVQEAIDRVIEDIKAGKKPEMPQIIVTAEKAV
EAGRFSNPYAKAKAMAAYFIAEKVADINVRGCFVEKDYNVYVPLVASAHEMMRIAAILAD
EAREIEKYGDKLFRDPHSREGKILSKTELISKPQ
>A0A133UKM3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|candidate division MSBL1 archaeon SCGC-AAA259E19|TrEMBL
MNEKIRVGFVKLGNIGTSTMLDLMLDERAEREDVDFRVVTSGPQMTEENGREVSKKVLDF
DPNLILTASPNPTTPGPSAAREVLEDVDVPCIVIGDAPGAKISEELEEKGFGYIFINADA
MIGARREFLDPVEMALFNSYLIKTLAVTGALSAVQEEVDLTISKIKEDERYLPQLIVDRD
KSIDVAEFENPYAKTKAMAAFEIASKVADLTFEGCFKIQESEKYIPIVGSAHEMMRVAAK
LSDEAREIEKGENSVLRKPHYDDGSILRKRKFLASPE
>A0A832WGJ4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosphaera sp|TrEMBL
MVLKIGIIKVGNIGTSPIIDLILDERADRQDIDVRTISSGAKMGKKQIHEILPKIFDFNP
DLLIFITPNPNAVQPRNAWEELSKKDIPTVIIGDKPGEKSINRMKEKNLGYILIHADAMI
GARREFLDPTEMALFNADVLKVLSVTGTLRLVAGAIDKLLGQITENENIELPQLVVTAEL
AVFNAGFKNPYAMGKAIAAYNMASLVSEMNIKACFQTDEPDVYIPLVTASHELMSAAAKM
ADEAREIEKSNDTVLRTPHAKDGSVWVRQSLVDTYK
>A0A497ILV3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MVKVGFIKMGNIGTSIVIDLLFDEIAQREDSETRTFSSGAKMSKKEASQTEELKGWNPDL
VIMISPNAMAPGPVAAREIWKDVPTIVVADGPTKKEGRQKLEDAGFGYIVLTVDPLIGAK
REYLDTVEMVNFNADVTKTLAVTGAIRLVQETIDGVIEELKAGKTPTMPHILAKPEKCVE
YGGFANPYAKAKALAALHMLNKVAEINTPACFMMKDLVDIASTAAAGHEVARIAAILADE
AREIEKSNDRVSRKPHAKDGKILSKTRLYEKPQ
>A0A7C4CVC8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MASGKPPVVKVGILKLGCVGTAPLLEYLLDERADREDIDVRVVSSGAKMDPDKAEEVARK
LIEFKPHFAAVVSPNAALPGPTKAREILLEAGLPVIVISDAPAKKAIQSLEAKGFGYIVV
EGDAMIGARREFLDPVEMACFNANIIKVLAITGAYNVIVEQLDKVIEDLKEGRKPELPKV
VVDKEVALKAAGFNNPYAKAKAMAAYETARKVADLTVEGCFKVQEWERYVPLVAAAHEMM
EVAAKLADEARELEKPADTLSRRPHARDGTLMSKLKLIEKPVKIKK
>A0A7C4G7I5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MTVRIGFLKLGNIGSAPLIELLLDERAERQDIIVRVVSSGAKGVQEVNEAEEVAKKILEF
TPQLIIITSPNAATPGPTRAREIIALSKIPTIIISDSPAKKALKSIEDLGMGYIIVEADA
MIGARREFLDPIEMALFNADLIKVLSITGVYNILFETIDKAITALKEGKSVELPKIVIDK
EIAVKSAGFSNPYAYAKAMAAYEISRRVADLTVEACFKVKEWERYTAINAAAHEMMLIAA
KLAEEAREIEKYGDTVVRKPHFDDGTILFKRKLIEKPIKQT
>I1XGE1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methylophaga nitratireducenticrescens|TrEMBL
MSKRSIIHMLNPMKQNSPFDINMALDAGYDIIMPYNNVELNEVASLTQDAIFSRGPSGVK
KTGMFIGGRDIGLAMDMLDAAKSAMVPPFEIPVFADPSGAFTTAAALVACVERELKKQFK
QDYKGVKAVVFGGTGPVGLATAVIAALQGAETTIVDHFSLDTALQFSDEARKRYGVNLRA
TTAASDADKARLLSDADVVFCTAKAGIQVLNASVLGDAKQLKVAGDVNAVAPLGIEGLEL
MDNGKPLKFASQCPKAVGIGALAIGNVKYKLQQALLRETLESDKPVYLDFRNAFEGARKL
V
>A0A497IRX4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MVKVGFIKLGNIGMSLIVNLLLDERADREDIDVRVAGTGAKMGKPEAEDVLSFLKWEPDL
LIVTSPNAALPGPKIVREAFEGKPCIVISDGPAKKAVDSMKEKGFGYIILPGDPMIGARR
EFLDPTEMALFNTDVLKVLSACGASRLVQEEIDRVIEEIKAGKDVTLPQIIATAEIVTER
ANFSNPYARAKAIAAYSMAEKVGELDSKACFMMKDPEAYTMMVAAAHELIREAALLADEA
REIEKGQDTLSRAPHAKSGELLSKQGLMEPLK
>A0A7L4PK28|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MFKIGFIKLGNIASSMVVDLALDEIAERTDLSTRVITFGPKMTKVEGEAAAELKSWGPQL
VVISSPNAATPGPTLAREHFKDLPTIVISDGPTKKEARDALAAEGFGFIILPVDPLIGAK
REFLDPAEMALFNADGLKVLSICGGVRLVQEEIDRSIASVAAGGKELPHILATPEKCAER
MDFVNPYARAKATAALYMAQTVASIDAQACFRLKELEAIALTAAAGHEVMRAAAMLADEA
RELEKAGDSVSRKPHARSGEILKKVKLLDKPEKA
>A0A662R5B1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MTDVKIGFVKLGNLGMSQVIDLILDEIAAREGIMVRTLGTGAKMSPDEAKDTEALIKHWD
PDFVVMISPNAGAPGPTAAREIYKNTPTIVVSDGPDKKDARQALKDAGFGSIILKVDPLI
GAKREFLDPTEMASFNSDAMKVLSTCGVVRMIQEELDKVVDQVASGKSGKDLELPYILAT
PEKCVERGYFENPYAKAKALAALHMANTVAAINFPACFIHKDVEKVTLTAAAGHELMNAA
ACLAREAREIEKSNDTVFRQPHAKAGNLLTKTKLYDKPA
>A0A7C5SWN0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Acidilobales archaeon|TrEMBL
MSQEGKVVRIGIIKPGAIGTSVILEYLLDERADRKDVDVRVYGTGSKMVVDENLLNVAIQ
ANHDLYIVAAPANVKVIKKIARKLKEAGKRVIIISDEPVKNSAKDFEEAGYGYIIVYGDP
MIGARREFLDPTEMALFNAYVLAVLSATGALRIVAKAIDSVIEALKEGKEPELPRIKLSK
KKLEEEAGFSNPYALAKAIAAYEMARKVSELTSEACFKEQEPERYITLAAAAHEMIRYAA
KLAEEARELEKPTDSLLRTPHHSSGKLLSKTKLLEKPR
>E3GZ78|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermus fervidus (strain ATCC 43054 / DSM 2088 / JCM 10308 / V24 S)|TrEMBL
MVVKIGVIKCGNIGTSPVIDLLLDERADRPNIDVRVIGSSAKMNPEQVEDVVPKMLDMDR
DLVIFISPNPGAPGPAKARELLSESDVPSIIIGDAPGKRVKDEIEKQGLGYIIVEADPMI
GARREFLDPTEMASFNADVIKVLACTGAYRLIHKTLDDLISDLEAGKEIELPKLIIDSEK
AVEAGEFENPYAKAKAMAAYEIAAKAADLDVKGCFMVQDPEKYIPIVASAHEMVSIAAKL
ASEAREIEKSNDTVKRTPHGKKGELLEKVELMAKPK
>A0A850MJC5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Helarchaeota archaeon|TrEMBL
MVVKIGVVKAGNIGISPVIELLLDERADRENIDVRVVGTGAKLNPKQCEEVAKKILDFNP
DLVIFLSPNAGLPGPGKAREILADSDVPTIIISDAPGKKAVEDIEAKGQGYFILTADSMI
GARRPFLDPVEMALFNSNILAVLAITGVLPAVYLEIDKVIEQIDKGDKPDLPKIVVNQDK
AIAAANFSNPYAKVKAMAAFEICRRVADVNVKGCFKTKGRENYMPIVGSAHEMMREAMIL
ADQAREIEKKGNTVIRRPHAPDGKVLSKRDFAEKPV
>A0A2V3JPM5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|ANME-2 cluster archaeon|TrEMBL
MSDVKIGFVKLGNLGMSQVIDLILDEIAARQGIAVRTLGTGAKMGADEAADTKALIEHWD
PDFVVMISPNAGAPGPTAAREIYKDTPTIIVSDGPDKKDARQALKEAGFGSIILKVDPLI
GAKREFLDPTEMASFNSDAMKVLSACGPVRLIQEEFDKVIDQVAAGKSGKDLELPYILGS
PDKCVERGCFENPYAKAKALAALHMANTVAAINFPACFMLKEVEKVSLVAAAGHELMGAA
AVLAREAREIEKSNDTLFRQPHAKMGELLSKTKLYDKPT
>A0A7J9T2Q3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|ANME-2 cluster archaeon|TrEMBL
MAKVGFIKLGNLGMSQVVDLILDEIAARKGIEVMSFGTGAKM
>A0A124G5N9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon 53_19|TrEMBL
MFICLFIKKGSVLKFFERCNSMVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATS
GTKLQPEDIDRVITNMKAWGPDFCVVVSPNGVLPGPTGAREELAKAGIPVVVITDDITTK
KEQFDTLKASSFGYIIMKADAMIGARREFLDPVEMADYNSNLVKVLALTGAFTKLQVELD
KVIDQVKAGKKGADLVLPKVVMTSDKAVDGAFNNPYAMAKARAAYEIAQSVAGVNVKGCF
MTKEWEKYIPIVCSAHEMMRQAAALCDEARELEKGADCIIRSPHKKDGVIVTKTKLISKP
E
>A0A843DCF3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter sp|TrEMBL
MVVKIGIVKSGNIGVSPVLDLLLDERADRPNIDVRVFGSGAKMNPEQVEDVVPKLEQFNP
DFCIFISPNPGAPGPAKARELLSEMDKPAVIIGDAPGKSKTEEMDEQGLGYVIVMSDPMI
GAKREWLDPTEMAIFNSDILKVLAETGALRLVQNTIDDIINTVDNGDEIELPKLIITAEK
AVDVAGFENPYAKAKAIAAYEMAGAVANLDMKGCFMTKGYENFIPLVAAAHEMAACAAKL
ASEAREIEKSNDTVLRTPHMKEGETGSKRDLISKPE
>A0A843IN71|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter sp|TrEMBL
MVVKIAIIKSGNIGTSPVIDLLLDERADRPNIDVRTFGSGAKMNPEQVEDVVPKIDAFEP
DFAIFISPNPGAPGPAKARELLSEKDIPAIIVGDAPGKGKKDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNSDILKVLAETGALRLVQKTIDDVIAQAEAGEIELPKLIITAEKA
AEAGGFANPYAKAKAIAAYEMAGSVANLDMKGCFMTKGYENFIPLVAAAHEIAACAAKLA
QEARDIEKANDTVLRTPHMKEGNPGCKTDLISKPE
>A0A843LEW9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoregulaceae archaeon|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVNNMVAWKP
DFAIVVSPNGVLPGPTGARERLAAAGIPTLFITDDVTTKKEWAEIKDGKFGYIIMKGDAM
IGARREFLDPIEMADYNGNLVKVLALTGAFRKLQNAIDQVIDQVKAGKKGADLAMPKLIV
SSDKAVDGEFTNPYALAKARAAYEIASAVAMVNVKGCFMTKEWEKYIPIVTSAHEMMRAA
AVLCDEAREIEKAGDGIIRKPHKKDGIIVSKTKLISKPE
>A0A2I0NIM8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Methanoperedenaceae archaeon HGW-Methanoperedenaceae-1|TrEMBL
MVKVGFIKLGNLGTSQVIDLLLDEIAAREGIAVRVFGTGAKMGKDEAADTAYFKKWKPDF
AVMISPNANAPGPTAARELWKDIPTIVVSDGPTKKDDRQKFEDAGFGYIILPVDPLIGAK
REFLDPVEMVSFNTDAAKVLTVCGAIRLVQEAIDNVIDQVAAGTSPLVLPKILGKPEKCV
ESAGFSNPYAKAKALAALHIATKVAEIDFPACFVLKDVEQVALTAAAGHEAMRAASKLAD
EARELEKANDSVLRKPHAKAGHLLTKTKLLEKPQ
>A0A6M5YQ74|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Frigoriglobus tundricola|TrEMBL
MSDKPTILVQLDTDPLPSVFDRVVAVDAGVQHVFSYGGVTPENVVPLVHGCIFTRGGKDL
SRTAIFVGGSDVAAGEAVLAEVKKHLIPQYGLSVSLLLDSNGSNTTAAAAVRAAGRHIDL
STAKSLVLGGTGPVGQRAVRLLAKAGGHVGVGSRRKDRAEAVCAAISAHVPRAKVEAVSV
SSSADAPAALEGCNLVIAAGAAGAVLLPKKYRAGNRSIRVLIDLNGVPPAGIEGIEPPDK
GTDRDGVICYGALGVGGTKMKVHRAAIHKLFEANNAVLDVEEVYNLALQLP
>A0A7J2N350|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MNQLRIAVVKFGCIGSSPLIEIALDERANREDILVRVFSTGGKMDAENCIDVADAAVKFN
PQLIVNVTPNAALEGPRKGRMHLKDKLPNIPIIVISDEPAKKAEKDLKENGFGYIIIQAD
PMIGARRDFLDATEMVLFNSDILKVLAVTGVIRMLIAEIDKVISTIKSGGEVKLPQIIAD
AYFVVENYGGFSNPYAKAKAIASYEAARRVARLSTTGCYVLKDREAYMPMVAAAHELLRI
AAKLADEAREIEKSNDTVYRTPHVKSGEKRYKVKFMEKAHR
>A0A832WXG8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MTEQQSKKIGIFKCGNIGTSPLLELLLDELADRQDIKVRTVTTGSKMGLDDVEEALPKIF
EFNPDLFIVISPNTALPGPAKAREAISSSGRPGVVISDSPAKRAKADIEKQGLGYIIITG
DPMIGXIRDNAELSNPYAKAKAMAAYAMAEKLAEINVQACFMEKESEKYIYLVACSHEIA
QIAAKLAEEAREIEKYNDTLLRKPHSKSGKIKTKSKLMQPLAFVEKPQDEGST
>A0A7J3XV13|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVKVGIVKLGCVGTAPLIEFLLDERADRNDIDVRVVSSGAKMDPEKAEEVAKKLLDFKPD
LAVVVSPNASLPGPTKAREVLRAAGLPVVVVSDAPAKKALGDLEAKGFGAIIVEADAMIG
ARREFLDPVEMACFNADIIKVLAATGVYNLLVNYLDKAIADLKQGKAPELPRVVVDKEAA
VAAAGFSNPYAKAKAMAAFETARRVADLTTEACFKIQEWERYTPIAAGAHEMMRYAAFLA
DEARELEKYGDTLQRMPHARDGTLMKKTKLMEKPVKTQ
>A0A842MV28|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVKVTIVKTGYIATTTLIDALLDERASRENVSVRVVSSGCKMDKDEAEAAAKLATQVPTD
LYVVISPNAGLPGPSIVREVLKETGKPIIIVSDEPSRKKAKQLGEEEGIGYLVLYGDPMI
GAKRPFLDPVEMALFNADAIRVLSVTGVFRLVHSEIDRVIEEIEQGKEPELPMIVVNKTR
ALEYSGLKNPYARAKAMAAFEAARKVADLDVEGCFKTQEASNYIPIVAAAHELMRAAAML
CDEAREIEKANDSVERLVHFRDGTLKRKTELLGKFE
>A0A497L298|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MRIGVAKCGNIGTSVLLDILLDERAERGDIIIRSVGSGPKLTPEEVREVVGKLLDFKPDL
VLLASPNAALPGPTAGRELLAEAGVPTIVITDGPGRKAVKDIEAKGMGYIIVPADSMIGA
RREFLDATEMAIYNADLVRVLACTGVYHALVEAIDKAIGGLKAGREPELPRLVLGRDEAV
GAARFSNPYARAKAMAAYEMASKVADLTVEGCFKLKEWERYTQVVAAAHELMREAARLAD
EAREIEKYGDTVFRAPHNRKGILLSKTKLVEKPKKPEG
>A0A497KZY0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVRIGFLKLGNIATAPMVELLLDERAEREDMEVRVLTSGANMGPEQSEDVANAMLALKPD
LVFVVSPNAATKGPTRAREVLAEAGIPVVVISDGPKKLLEALEKRGMGGIIVEADAMIGA
RREFLDPIEMAIFNADTIKVLSVTGVYNVVYEAIDALIEQLKAGKKPELPLLNVTRKKAL
KAAGFSNPYAQAKAAAAYEMAKRVANLTTQACFKEKDWETYTALCAAAHELMRSAALLAD
EAREIEKYGDAVLRKPHYNDGSILRKRKLIEKPR
>A0A7L4PZF1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVNNMVAWKP
DFAIVVSPNGVLPGPTGARERLAAAGIPVVFITDDVTTKKEWADIKEGKFGYIIMKGDAM
IGARREFLDPIEMADYNGNLVKVLALTGAFRKLQMALDQVIDQVKAGKKGADLVLPKLVV
TSDKAVDGEFTNPYALAKARAAYEIAQSVAMVNVKGCFMTKEWEKYIPIVSSAHEMMRCA
AVLCDEARELEKAGDGIIRKPHKKDGVIVSKTKLISKP
>A0A0Q1A782|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoculleus sp. SDB|TrEMBL
MVIKVGVAKLGNIASGVMVELLLDERADRTDMQTFMATSGTKLEVEDVDRVVSNLKAYGP
DFAIVVSPNGVLPGPAGAREALKAAGIPVIVITDDVTTKKEWPELKESGFGYIIQKADAM
IGARREFLDPIEMADYNGNLVKVLSITGAFRKMQLAIDEVIDQVKAGKKGAELVLPKLVV
TADKAVAGEFTNPYAYAKARAAFEIAAAVAMVNVKGCFMTKGFENYVPIVASAHEMMRVA
ALLCDEARELEKGVDGVVRKPHKNDGTIVSKTALISKPE
>A0A1V5AQB2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosaeta sp. PtaU1.Bin060|TrEMBL
MFKIGFVKLGNIATSLAADLALDEIAERTDIEFKVISFGPKMTKKEGEASAELKAWGPQL
VVISSPNAATAGPTAAREIFKGTPTIVISDGPTKKEARDQLAAEGFGFIILPMDPLIGAK
REFLDPVEMALFNSDALKVLAACGAVRLVQEELDQAMAAIARGEAKLPTILATPDKCAER
MSFQNPYARAKAVGALHMAQTVASIDAAACFRLKELEQIALAAAAGHEVMRAAARLADES
RELEKAGDTVSRKPHARSGELMKKSRLLERPEKI
>A0A0A0BJM4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methylophaga thiooxydans|TrEMBL
MKKLLLHLDTDPVASTFDQAVAYDSGVDNIIAYGGATRDNVTPHVHGMIFTRGGKSLKNS
AIFIGGSNVAASDLVGEAVKKAFFGPVRVSVMLDPNGSNTTAAAIVRKVLTDFDVKGKNV
VILGSGPVGQRSALYLLKEGAAKVTMTSRSMQRTKAITEEMKVNYGVDVTPGETRSDEAV
KQLLADAHVAIAAGPAGVCVIPEAALENNSSLEVIADVNAVPPLGVAGIEVMDNGTEKNG
IRHYGAIAIGGFKMKVHQGAVSSLFDSNEQFLDETTIYDIACKIDNAQ
>G7WNZ3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosaeta harundinacea (strain 6Ac)|TrEMBL
MFKIGFIKLGNVASSLVADLALDEIAERTDVEVRSLSFGAKMTVKEAEMSAELKGWGPQL
VVIVGPNAATPGPTAARALYRDVPTIVISDGPSKKEAREALEAEGFGYIILPFDPLIGAK
REFLDPAEMALFNSDALKVLSICGSVRLVQEELDGAMASIISGAPRLPTILSSPEGCTDR
MAFRNPYARAKAIGALHMAQTVAGIDAAACFRLKELDRIALTAAAGHEVMRAAARLADEA
RELEKSTDSVSRRPHARSGAILAKTGLLDKPEPV
>E1RKC0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanolacinia petrolearia (strain DSM 11571 / OCM 486 / SEBR 4847)|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMETFMATSGTKLQEKDIDRVVENMKAYGP
DFCIVVSPNGVLPGPKGAREALAAAGIPCVVITDDITTKKDEFAALKETSFGYIIMKADA
MIGARREFLDPIEMADYNGNLVKVLAVTGAFRKLQIALDEVIDQVKEGKKGADLVLPKIV
MSSDKAVEGEFTNPYAYAKARAAYEMAQSVAGINVKGCFMTKGHENYTPIVASAHEVMRQ
AMLLCEEAREIEKSCDGVIRKPHKSDGTRVEKVKLIDKPW
>A0A5E4L349|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon|TrEMBL
MVVKIGVIKLGNLGTSQVIDLLLDEIAAREGIAVRVFGTGAKMGKDEAAETESFKKWGPD
FVVMISPNSMAPGPTAARDVWKGTPTIVVSDGPTKKEDREKLEQAGFGYIILPVDPLIGA
KREFLDPVEMVSFNSDAAKVLSVCGAIRLVQTEMDKVIDQVAAGTKPPALPKILGKPEKC
VESAGFANPYAKAKALAALHIATKVAEIDFPACFVLKEVDQIATTAAAGHEALRAAARLA
DEAREMEKANDSVLRKPHAKDGRLLTKTKLLEKPQ
>A0A2P0QMB3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon|TrEMBL
IELPKIIMTTDKAVDGEFTNPFALAKARAAHEIAMAVAGQNVKGCFMTKEWEKYIPIVAS
AHEMMRSAAMLCDEARELEKAGDSILRQAHKKDGSLVAKKKLVAKFE
>A0A524CNB0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MSKDNLLIGVHKNGTIGSSVLLSFLIDERAEGERVTFREVTSGPKMHPPEHCVETMEELL
KFNPELILMSSPNAALKGPSKAREMVGNIPTIVISDAPAKKAKDEMKEKGIGYIIVECDS
MIGARRPFLDPIEMSIFNSDLLKVLAVTGVFNILVEELNKVIMDMLDGKKPELPQLVIDS
SMATERARFSNPYARAKAIAAFELAAQVSKITGKACFVLKEREEYMPLLAAAHEMMKTAA
NLCEIAREIEKSNDTVLRTPHRSSQELLEKRKLHEKEK
>A0A7K4D0L0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
AIIISDAHSKKAKDEIVGRGNMGYIVLQADSMIGARREFLDPTEMTIFNADLLKVLALTG
VIKLVVKVIDDVITAIKKNEKPVLPQLIVTKEQAIQAANYLNPYARAKAMAAHEMAESVA
KLNTEGCFKLSHREEYMPVIAAAHEIMRAAAKLADDAREIEKGTGQVHRSPHYKDGKILN
KTGFVDKPE
>A0A401HQS5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanofervidicoccus abyssi|TrEMBL
MGVEQVEEVTKKMIEDIKPDLIVFISPNPAAPGPKKARELLSKCGIPSVIIG
>A0A257MKN5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosaeta sp. NSM2|TrEMBL
MFKIGLVKLGNIATSTVIDLALDEIAERSDIEFKVISFGPKMTKKEGEASEELKAWQPQL
VVICSPNAATAGPTAAREKFKGTPTIVISDGPAKKESRDALAAEGFGYIILPMDPLIGAK
REFLDPAEMALFNSDALRVLAAGGAIRLVQEELDRVMAGISAGEANLPVILATPEKCAER
MHFSNPYARAKAVGSLYMAQTVAGIDAAACFRLKELEAIALTAAAGHEVMRAAARLADEA
REMEKANDSISRHPHARTGELMNKTGLLDKPEKI
>A0A832B128|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus sp|TrEMBL
MTKVKVGVLKMGAIGTAVILEYLLDERADREDIEVRVVTSGAKMQPEEAVVAEKLKEFNP
DLIIVASPNAALPGPKAAREAFAGKPVIVISDAPAKKAKDELKEKGFGYILINADSMIGA
RREFLDPTEMALFNSDVLKVLAATGTLRVVQEAIDKVIEDIKAGKKPELPQIIVTAEKAV
EAARFTNPYAKAKAMAAYFIAEKVADINVRGCFVEKDYNVYVPLVASAHEMMRIAAILAD
EAREIEKYGDKLFRNPHSREGKILSKIELISKPQ
>A0A0E3NNM3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp. WH1|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMGPADAADTESFKQWNADF
VVIISPNAAAPGPTAARELWKDVPCIVVSDGPTKKEAREAFEQDGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSICGVVRLIQEELDKVAEQVASGKSGKDLELPHIFAKPEK
CVEHAGFANPYAKAKALASLHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAIL
ATQAREIEKSNDTVFRQPHAKNGALLKKVQLYEKPQ
>A0A1V5ZC55|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Euryarchaeota archaeon ADurb.Bin165|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVTNMKAWGP
DFCIVVSPNGVLPGPKGAREALAAAGIPCVVITDDITSKKEEWEALKASEFGYIIMKGDS
MIGARREFLDPIEMADYNGNLVKVLSVTGAFRKLQVALDEVIDQVKAGKKGKDLALPKIV
MTSDKAVEGEFSNPYAYAKARAAYEIAQAVAGVNVKGCFMTKGFENYTPIVASAHEMMRQ
AMLLCEEAREMEKATDAVIRKPHKNDGTRVAKKTLISKPE
>A0A7C4D5I7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MNRTVRIGVLKAGCLGSLPLLEFLLDERAEREDIGVRVIGSGAKVTVEECIECANEILKQ
NPDIIIFVGPAQTTSGPTEARKVLRKAGKPVVVISDTPAKRIIKELEENGFGYIIVEADS
MIGARREFLDPSEMALYNSDVIKVLAITGVLNIIVEELDKAISAIKSGEKPILPRVVIDG
KVVAERSGFSNPYARAKAMAAYEMAKQVSAMTIEACFKIYDPGLYIPLVTAAHELMRVAS
KLADEAREIEKENDSVLRKPHYKDGSIGVKRSLMEKPSKITS
>A0A7C4HZT1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MSGVVKVGVLKAGCIGSLPLLEFLLDERAEREDIRVRVVGSGAKVTPEDCIEGAEQIIRQ
NVDLVIFIGPAQTTQGPSEARKILRASNKPVIIISDSPARRIIKELEEYGFGYIIVEADS
MIGARREFLDPLEMALYNSDVIKVLAITGALNILVEELDKVINAIKFGEKPVLPKIIIDS
RRAVEATGFSNPYARAKAIAAYELAKQVSTITFEACFKIHEPEAYIPLVAAAHEIMRTAA
KLADEAREIEKKSDSVLRRPHFKDGVRGEKRLLMEKPRRIAI
>A0A3R7X664|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocalculus sp. MSAO_Arc2|TrEMBL
MVVKVGIAKLGNIAAGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVTNMKAWGP
DFCVVVSPNGILPGPTGCREELAKAGIPVVVITDDITTKKEKFEELKASTFGYIIMKGDA
MIGARREFLDPVEMADYNGNLVKVLALTGAFTKLQVELDKVIDQVKAGKKGADLVLPKMV
VTSDKAVEGEFVNPYAMAKARAAYEISQSVADVNVKGCFMTKEWEKYIPIVCSAHEMMRV
AAMLCEEARELEKAGDSVIRKPHKKDGVLVSKTKLVSKPE
>A0A0F8ET88|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp. 2.H.T.1A.3|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVCGTGAKMGPADAADTESFKQWNADF
VVIISPNAAAPGPTAARELWKDVPCIVVSDGPTKKEAREAFEQDGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLIQEELDRVTEQVASGKSGKELELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
ATQAREIEKSNDTVFRQPHAKSGALLKKVKLYEKPQ
>A0A7J4IHM0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoregulaceae archaeon|TrEMBL
EKYIPIVASAHEMMRAAAVLCDEAREVEKAADGVVRKPHKKDGTIVSKTKLISKPE
>A0A1V5IGQ0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Euryarchaeota archaeon ADurb.BinA087|TrEMBL
MLALTGAFRKLQNAIDQVIDQVKAGKKGADLAMPKLIVSSDKAVDGEFTNPYALAKARAA
YEIASAVAMVNVKGCFMTKEWEKYIPIVTSAHEMMRAAAVLCDEAREIEKAGDGIIRKPH
KKDGIIVSKTKLISKPE
>A0A832PDC3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermobacter sp|TrEMBL
MVAKIGVLKCGNLGTSPVIDLVLDERADRPNVEIRVMGSGTKMNPDDIEFVVPKMLELDR
DFVIFISPNPGAPGPARARELLSEADVPAMIVGDSPGLRVKDEIEEQGLGYIIVKADSMI
GARREFLDPTEMAAFNADLMKVLALTGAYRVVHDTLDAMIAEVEAGKEVTLPQVVITRDV
AVEAAGFQNPYAKAKAMAAYEIATKVADIDVEGCFMVQDPEKYIPIVASAHEMMSTAARL
AEEAREIEKSNDTVKRTPHGKEGETLSKAKLLEKPS
>A0A497JAL4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Hydrothermarchaeota archaeon|TrEMBL
MIRVGVLKTGNIATSLLVELLLDERADREDIDVKVISSGAKMTKEQVELTSKLLEFNPDL
VIYITPNCSLPLPKKIISKLVEKKPTIVISDAPGIKIKDELEKLGAGYIFVKADAMIGAR
REFLDPIEMAIFNADMLKVLAITGALRAVHEAIDNAIESIKAKKVNLPKLVLDKLAVARY
SGFANPYALAKAISAHIISEEVGKLNVEACFMTKTKEEYITKVASAHEMLRIASKLADEA
REIEKANDNVLRKPHSKQGLILEKRRLFDKFNKPRS
>A0A832W570|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoculleus sp|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDIITFMATSGTKLQPEDIDRVVTNMKAWGP
DFCIVVSPNGVLPGPTKAREDLAAAGIPCIVITDDVTTKKEQFEALKASNFGYIIMKADA
MIGARREFLDPIEMADYNGNLIKVLATTGAFRKMQMELDKVIDQVKAGKKGADLVLPKVV
MTSDKAVEGEFSNPYALAKARAAYEIAQEVAGVNVKGCFMTKEWEKYIPIVASAHEMMRQ
AMLLCDEARNLEKAVDGVIRKPHKKTGEIVSKTALISKPE
>A0A7C3REH2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus fulgidus|TrEMBL
MVKVGILKMGAIGTALLVEYLLDERADREDIEVRVVTSGAKMQPEEAVVAEKLKEFDPDL
VIVVSPNAALPGPKAAREAFEGKPVIVISDAPAKKAKDELKEKGFGYIFINADSMIGARR
EFLDPTEMALFNADVVKVLAATGAFRIVQEAIDKVIEDIKAGKQPELPQIVVTAEKAVEA
GKFSNPYAKAKAMAAFYIAEKVADIDVKGCFIEKDPEKYIPLVASAHEMMRVAAILADEA
REIEKGSDTVYRNPHARDGKILSKTQLMTKPE
>A0A256ZNU6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon ex4484_218|TrEMBL
MAVSPVKVGVLKLGCVGTAPLLEYLLDERADRGDIKVRVVSSGAKLDPEEAEDVAKGILQ
FKPNFAIVVSPNAALPGPTKAREILKEAGLPVLVVSDLPAKKAAKDMDAKGFGYFVVEAD
AMIGARREFLDPVEMACFNADIIKVLALTGVFNLLVKCVDGIIQAFKEGKQPELPKIVVD
KAKALKEAGYQNPYAYAKAMAAFEAARRVGDLTTEGCFKIQEREVYIPIVAAAHELMRYA
SKLAEEARETEKSEDMVLRKPHGKDGSLLSKVKLMEKPEKK
>A0A7Z7AW87|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanolobus vulcani|TrEMBL
MAKIGFIKLGNLGMSQVIDLVQDEIAAREGISVRVFGTGPKMGKDEAAATEELKKFDADF
YVMISPNSSAPGPTAAREIYKDVPCIVISDGPTKKDDRAALEEAGFGYIIMTVDPLIGAK
TEFLDPVEMASFNSDAMKVLSTCGVVRLIQEELDKVAAMADEGKELELPHILAKPEKCIE
RAGFNNPYAKAKALAALHMADSVAKINFPACFMMKEIEQVTLTAAAGHEMMRAAAQLAID
AREIEKANDSVFRQPHAKKGYQMTKTALYEKPQQ
>A0A7C3A3U5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MEEVVKIGVVKTGNIGTAPLLELLLDERADRKDIDVRVVGSGAKLNPEQAEEVARKVLEF
NPNLVLTVSPNAALPGPSKVREVLAEAGVPTIVISDAPGKKAKEDIEGKGQGYIIINADA
MIGARREFLDPIEMALFNADVIKVLAITGALTVIYQEIDKVIDAIKKGEQPTLPRIVVNK
NVAVEAANFSNPYAKAKAIAAYEAASTVADLNVEGCFKVQEYEKYVPLVAAAHELMRQAA
LLADEARELEKAGDSVLRMPHKKSGEIVSKRALISKPS
>A0A7J2YEC5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVKVCILKLGCIGASPLLEYVLDERADRGDIEVRVLSVGAKMTEAHAEELVKKALAEDYD
LYIIPSPNASLPGPTKVRNALGEKGKNVIVISDAPARRITKELEEKGFGYIIILADSMIG
ARRGFLDPVEMTLFNADVIKVLAATGVVRLLQVELDKVINSLKAGEKPSLPKIVVDKEVA
T
>A0A7J2IXG6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MGEGRPIKVGVAKVGNIGASVLLDILLDERADRGDIVIRVVGSGPKLMPEEVKEVVSKLL
ELEPDLVLIASPNAALPGPSAGRELLAKAGVPTIVISDAPGKKAVKDIEEKGMGYIIIPA
DSMIGARREFLDPTEMAIYNADLLKVLACTGVFHALVEAIDKAISDLKAGREPELPKLIL
GRDEAVRAARFSNPYARAKAMAAYEMAAKVADLTVEGCFKVREWEHYTHIVAAAHEMMRQ
AAKLAEEAREMEKQGDTVFRAPHNKKGMLLRKTKLIEKPRKVEVEGQVGGQAEA
>A0A7J3KTQ1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
VIQIELDRVIEYLKKGEELKLPKIVVDRKVAVEAGQFTNPYAKAKAIAAYEAAAKVADLT
VEGCFKIEDWVEYTSIVAAAHELMSYAAKQASEAREIEKGLDTVYRSPHNRKGEILSKRK
LIEKPSKPG
>A0A497KRC6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MARLGFLKLGNIATSPMVELLLDERAEREDMEVRVVASGANMSPGQAEEVAKAMVEMKPD
IVFVVSPNAATPGPKKAREVVAEAGIPVVVITDGPKKLLEELAERGMGGIIIEADSMIGA
RREFLD
>A0A497L1S1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVRVTFLKIGFLGVSNLIEALLDERASRRGLSIRVVSTGCKMDVEEAIDAAKLAASIPSD
LYVVVSPNAALPGPREARRLLKETGKPIIVVSDEPTKKIAEELGEEGFGYILIYADSMIG
ARREFLDPVEMALFNSDVLKVLAITGVLRLVHMELDRVIRQIEAGEQPELPRMRITKERA
LEMSGLNNPYAYAKAMASFEMARRVAALSTEGCFKVKERERYIPIVAAAHELMRWAAMLA
DEAREMEKANDTVTRIVHFRDGSLRRKKKLYEKYEALTDL
>A0A842LQU1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobi archaeon|TrEMBL
MTRIGFVKLGNIGISTVVDLILDERADREDIEVRTISSGSKMSPEVVEDLKKINELSPEL
LVVVSPNASLPGPKKMREAVEVPCIIISDAPAKKAVKKLEEGGFGYIIISGDPMIGARRE
FLDPTEMTLFNAEVLKILSVSGVVRIVQDELNRALESIKRGELYLPKRIVEIDDIISLEF
SNPYAKAKAVAAYSIAEKVAELNVRACFMEKEREKYISMVAAAHEMIRIASKLSDEAREL
EKAVDGVIRTPHSRDGRTLFKRALMEVFQK
>A0A843DDJ2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocorpusculaceae archaeon|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMMTFMATSGTKLQKEDVDRVVSNLKAWQP
DFAIVVSPNGVLEGPVGARDELAAAGIPVIVITDDVTTKKEGWEALKASNYGYIIMKADA
MIGARREFLDPVEMADYNGNLIKVLATTGAFRKLQQELDKVIDQVKEGKKGAELVLPKLV
VNSDNATKGEFTNPYALAKARAAYEMAQSVANINVKGCFMTKAWEDYIPIVASAHEVMRQ
AAALCDEAREIEKGCDGVIRIPHKKTGELVHKTALISKPE
>A0A524CKG1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MTFKLGVIKCGNIGCSPILELLFDERADRENIDAIVIGSGAKLNPEQCEEVTKLMVEQKP
DLIFITSPNAGLPGPSNARKILHESGIPSIIITDAPGKEAVEDCEAKGIGYFIVVADSMI
GARRPFLDPIEMAIFNSQILSILALTGVFRLIINETEKVIKQISSGKEPELPGIVINKKN
AIEAAGYANPYARNKAMAAHEICKSVASI
>A0A1V4TPF5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoregula sp. PtaB.Bin085|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLEPADVDRVVSNLKAYKP
DFCIVVSPNGVLPGPTSAREELAKAGIPVVIITDDVTTKKEWEGVKASKFGYIIMKADSM
IGARREFLDPVEMADYNGNLVKVLALTGAFRKLEVALDKVIDQVKAGKKGDAIELPKIIM
TTDKAVEGEFTNPYALAKARAAHEIAMAVAGQNVKGCFMTKEWEKYIPIVASAHEMMRSA
AVLCDEARELEKAGDSIMRQAHKKDGTLVAKKKLVAKFD
>A0A1V4UWH3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosaeta sp. PtaB.Bin039|TrEMBL
MFKIGFIKLGNIASSLVVDLALDEIAERNDIEAKVLTFGPKMTKKEGEAAAELKAWGPQL
VVITSPNAATPGPTAARAVFKDLPCIAISDGPTKKEARDAMAAEGFGFIILPVDPIIGAK
REFLDPAEMAIFNADALKVLGVCGGVRLVQEEIDRSMASVAAGKPALPQILATPERCVER
MGFANPYARAKATAALYIAQTVASLDSQACFKLKELEAIAIAAASGHEAMRCAAALADEA
REIEKAGDSVSRRPHARSGEAMSKVRLLDKPERI
>A0A1D2WT91|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter sp. A54|TrEMBL
MVVKIGIIKSGNIGTSPVLDLLLDERADRPNIDVRVFGSGAKMNPEQVEDVVPKVDQFDP
DFCIFISPNPGAPGPAKARELLSEKDIPAIIIGDAPGKGKKDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNADILKVLAETGALRLVQNTIDGVIDGAAAGNIELPKLIITAEKA
VEAAGFENPYAKAKAIAAYEMAGAVANLDMKGCFMTKGFENFIPLVAAAHEMAASAAALA
DEAREIEKGNDSVLRTPHMKEGNTGCKTDLISKPE
>A0A1I6X1R4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina thermophila|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFSTGAKMSPAEAADTENFKQWNPDF
VVIISPNAAAPGPTAAREIWKDVPCIVVSDGPTKKEAREALEQEGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLIQEELDKVTDQVASGKSGKELELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
AMQAREIEKSNDTVFRQPHAKNGALLKKVKLYEKPQ
>A0A7C4GV39|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKKVKVGVFKCGNIGTAPLLELLLDELADREDISVRVITTGAKMLAEEVDEALPRIFDFN
PDFIVFISPNPAVQGPKRAREILLERKIPSIFISDAPGKRLKEEFEAQGFGYIIVMGDPL
IGARKEFLDPTEMAIFNSNIIKVLAITGVYRIIQQEIDRVIQCCKDGLTFELPRLIVDTD
TIRENSDFRNPYALAKAMAAYELTKKIAEVNTRACFMEKEKEKYILLVACAHEIAEAAAH
LAEQAREIEKYADSLVRRPHSREGKLKIKERLMDSPIFEEVFR
>A0A846Q9D0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Nitrososphaeria archaeon|TrEMBL
MSKVVKIGIVKAGCIGTLPILEFLLDERADRTDIDVRVVGAGAKLGPEQCEEVATNMLDF
KPDLAIIISPNAALKGPTKGREILKSAGIPTIVISDGPTKKIADDLKAAGFGYIIIDVDA
MIGARREFLDPVEMSLFNADIIKVLSVTGVFNIVFEEIDRVIQALKDGKTPTLPTIKTNK
EKAAAASGLTNPYARSKAMAAYEVSRRVADVTVQGCFMVKEREKYIPLVAAGHEMMRYAA
RLLDEAREIEKGADTLARRPHHPDGTILKKKKLMEKPKRPGE
>A0A842Y7P9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MVKVGFIKLGNLGMSQVIDLVLDEIADKEGIEVRSFGTGAKMGKDEAEHTKHFKKYEADF
YVMISPNSSAPGPTAAREIWKDKPLIVVSDGPTKKDDRQALQDAGFGYIIMKVDPLIGAK
REFLDPVEMASFNSDAMKVLSTCGVVRLIVNAFDAVIDQADAGKDLELPHILVTAQKAIE
SAGFNNPYAKAKALAALHMADKVAEVNFPACFMLKEVEQVTLTAGAGHEMMRAAAQLAID
AREIEKANDSVYREPHAKKERGYRKKTKLYDKPQ
>A0A497IWY4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MSRIVDLVLDERADREDVDACVVASGAKMTAAHAESAAKALLQLDPDFAVVISPNAALPG
PKKARDLVKEGGKPCIVISDAPGKKAVEELKNDGFGYIILTGDPMIGARRQFLDPVEMSL
FNADVLKVLSVCGAVRLVQEELDAVIEQIKKGETPTLPQIIANAETVVSRASFANPYAAA
KAFAAYSIAEKVADINVQACFVVKEAERYVPMCAAAHEVMRYAALLADEAYEIEKYGDSL
LRTPHARSGEILKKRKLLERPA
>A0A850M923|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Helarchaeota archaeon|TrEMBL
MVVKIGVIKAGNIGISPVIDLLLDERADRENIDTRVVTSGAKLNPEQCVEITKKILEFKP
QLIIFLSPNAGLPGPTKAREILAEAKVPTIIISDAPGKKATEDIEAKGQGYLILVADSMI
GARRPFLDPVEMALFNANILAVLAITGVIPLVYTEIDKVIDQIERGETPSLPRIVVNKKN
AIPAAGFTNPYARNKAMAAHELCKAVAGVNVEGCFKTKGRENYMPIVGAAHEMMREAFLL
ADQAREIEKYGNTVLRRPHAPDGKVLSKRDFAEKPV
>A0A843ESV6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter sp|TrEMBL
YEMAGSVANLDMKGCFMTKGFENFIPLVAAAHEIAAAAAKLAQEARELEKSNDTVLRTPH
MKEGNPGRKTDLISKPE
>A0A843LVH1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter sp|TrEMBL
MVVKIGIIKSGNIGTSPVLDLLLDERADRPNIDVRVFGSGAKMNPEQVEDVVPKVDQFDP
DFCIFISPNPGAPGPAKARELLSEKDIPAIIIGDAPGKGKKDEMDEQGLG
>A0A843F5R4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter sp|TrEMBL
EKSNDTVLRTPHMKEGNPGRKTDLISKPE
>A0A1F2P8R9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Syntrophoarchaeum caldarius|TrEMBL
MVKVGFIKLGNIGMSLIVNLLLDERADREDIDVRVAGTGAKMGKPEAQDVLSFLKWEPDL
LIVTSPNAALPGPKIVREAFEGKPCIVISDGPAKKAVDSMKEKGFGYIILPGDPMIGARR
EFLDPTEMALFNTDVLKVLSACGASRLVQEEIDRVIEEIKAGKEVTLPQIIATAEIVTER
ANFSNPYARAKAIAAYSMAEKVGELDSKACFMMKDPEAYTMMVAAAHELIREAALLADEA
REIEKGQDTLSRAPHAKSGELLSKQGLMEPLK
>A0A1F5DB35|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon RBG_13_60_20|TrEMBL
MVTVTIVKVGYIGTTTLIDALLDERSARSDIKIRVISSSVQMGEEDAGDAARIAASVPSD
LYIAISPNVSLPGPTKVREVLKATGKPIIVIGDEPSRKAAKGLAEEGIGSIVIYGDPMIS
AKAPFLDPVEMALFNSDVLRVLAVTGVFRLVHTTLDRVIEEIKAGQKPQLPQLIINKTAA
LAASDIKNPYAYAKAMAAYEASKEVASLSTEAVFKIEDKNEAIPVLAAAHELMRMAAKLA
DEAREIEKGNDTAVRLAHFKKGDLRRRVRLFDEPEK
>A0A843DPM1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocorpusculum sp|TrEMBL
RAAYEMAQSVANINVKGCFMTKAWEDYIPIVASAHEVMRQAAALCDEAREIEKGCDGVIR
IPHKKTGELVHKTALISKPE
>A0A257MCY2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosaeta sp. NSP1|TrEMBL
MFKIGLVKLGNIATSTVIDLALDEIAERSDIEFKVISFGPKMTLKEGEASEELKAWQPQL
VVICSPNAATAGPTAAREKFKGTPTIVISDGPAKKESRDALAAEGFGYIILPMDPLIGAK
REFLDPAEMALFNSDALRVLAAGGAIRLVQEELDRVMAGISAGEANLPVILATPEKCAER
MHFSNPYARAKAVGSLYMAQAVAGIDAAACFRLKELEAIALTAAAGHEVMRAAAKLADEA
REMEKANDSISRHPHARTGELMNKTGLLDKPEKI
>G0H2S2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcus maripaludis X1|TrEMBL
MVVKIGILKCGNIGMSPVVDLCLDERADRNDIDVRVLGSGAKMGPEQVEEVAKKMVEEIK
PDFIVYIGPNPAAPGPKKAREILSAGGIPAVIIGDAPGIKDKDAMAEEGLGYVLIKCDPM
IGARRQFLDPVEMAMFNADVIRVLAGTGALRVVQNAIDDMVFAVEEGKEIPLPKIVITEQ
KAVEAMDFANPYAKAKAMAAFVMAEKVADIDVKGCFMTKEMEKYIPIVASAHEAIRYAAK
LVDEARELEKATDAVSRKPHAGAGQILNKCKLMEKPE
>A0A8D6PYT2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocaldococcus sp. SG1|TrEMBL
MGETLVVKIGVIKCGNLGISPMIDLALDERADRKDIAVRVLGSGAKMDPESVEEVTNKMV
NEIKPDIIIYVGPNPGAPGPKKAREILSKSGIPSVIVGDAPGLKVKDEMEQQGLGYIIIK
CDAMIGARREFLDPVEVAMFNSDILRIIGGTGALRIVQNAIDEMITAIKEGRHVELPRIV
INEEKAVEAMEFTNPYAKAKAMAAFVIAEKVADVDVKGCFMIKDAERYIPIVASAHEMLR
YAAKLVDEARELEKAMDAVSRKPHASDGRILSKKKLMEKPQ
>A0A832UAA5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoregula sp|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLEPADVDRVVSNLKAYQP
DFCIVVSPNGVLPGPTGAREQLAAAGIPVIIITDDVTTKKEWEALKADTKFGYIIMKADS
MIGARREFLDPVEMADFNGNLVKVLAITGAFRKLQIAVDKVIDQVKAGKKGTELELPKII
MTTDKAVDGEFTNNYALAKARAAHEIAMAVAGQNVKGCFMTKEWEKYIPIVASAHEMMKV
AAILCDEAREIEKAGDSVLRKPHKKDGVIVSKNKLVAKFE
>A0A2I0D2B4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoregula sp|TrEMBL
MVVKLGVAKLGNIASGVMAELLLDERADREDMQTFMSTSGTKL
>A0A843KG19|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanolinea sp|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLEPADVDRVVSVLKAWKP
DYCIVVSPNGVLPGPTGAREQLAAAGIPTLFITDDVTTKKEWAEIKDGKFGYIIMKADAM
IGARREFLDPIEMADYNGNLVKVLAITGAFRKLQNALDGVTDQIKAGKKGAEVVMPKLVI
TSDKAVDGEFTNPYAMAKARAAFEIASAVAMVNVKGCFMTKEWEKYIPIVSSAHEMMRVA
AVLCDEARELEKSVDGVIRKPHKKDGVIVSKTKLISKPE
>A0A7K3YU25|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocorpusculum parvum|TrEMBL
PVEMADYNGNLVKVLALTGAFRKIQMELDKVIDQVKAGKKGAELELPKLVLNSDNSTKGE
FTNPYALAKARAAYEIAQAVAGVNVKGCFMTKEWTDYVPIVTSAHEMMRAAADLCDQARE
LEKGCDGVIRKPHKKTGEIVSKVALISKPE
>A0A7J3ZNL9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MSKVVRVGVLKAGCIGSLPLLEFLLDERADREDIQVKVIGSGARVTSEQCIEGAEQILKQ
DFDLIIFAGPAQTTQGPSEARKILRNSNKPVIIISDSPAKRIIKELEETGFGYIIVEADS
MIGARREFLDPAEMALYNSDVIRVLAATGALNIIVEEIDKVINAIKSGEKVILPKLIVDG
RRAVEAAGFSNPYAKAKAIAAYEIAKQVSTITFEACFKVQEPDLYIPLVATAHEMMRVAA
RLADEAREIEKGSDSVLRRPHFKDGTLGKKKRLMEKPQRTKLIS
>A0A7J2LM98|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MSKVVRLGIAKMGCLGSVPLLEFLFDERAERTDLDVRVVGSGAKLGPEQCVEVTKTLLNL
KPDFIIVAGPAQQTTGPKEARKLLADSGIPTLIISDGPMVRIKGELEKAGFGYIIVEADP
MIGARREFLDPVEMAIFNSDVIKLLACTGVFNVIVDAVDRIIESLKRGEKPSLPHIVVDR
NLALKAAEYSNPYARAKALAAFDLAKQVTSLHVEACFKLTDWKEYTL
>A0A550H4V2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MAQNQFKKIGIFKCGNIGTSPLVELLLDELADRKDIKVRTVTTGSKMGPEDVEDALPKIF
ELNPDLLIVISPNTALPGPGKVRERISSSGLPGIVISDAPGKRAKEEIEKQGLGYIIITG
DPLIGARKQFLDPIEMAIFNSNISKVLAMTGVYRIVHQEIDKAIYAIENEQKPDLPKLIV
DLKTVRDRSEFSNPYAKAKAIAAYGLAEKIAEINVQACFMEKESEKYIPLVTCAHEIAQT
AARLAEEAREIEKCNDTVVRKPHAKDGKLKVKTELMLPPVSEEDFSG
>A0A7J2LG81|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVVRVGFLKLGNIGTAPLVELLLDERAEREDVEFRVVGTGPKLTPEHAVDAARKLAEFRP
DIAIVISPNATLPGPTQGRQILAEAGIPTIVISDAPTKQIRQELEEKGFGYIIVEADPMI
GARREFLDPVEMALFNVDVIKVLAITGVFNLIQRELNAVIEAVKRGEKPTLPRVVVTRMK
AVEAAGFTNPYAKAKALAAYETAKNVAALTTAACFKIKEWEKYTLTAASAHEMIRTAAKL
AEEAREIEKSQDTVLRTPHHKDGTILTKRKLIEKPKRPE
>A0A497F5G7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Verstraetearchaeota archaeon|TrEMBL
MRVFDMNQRVVKISIVKIGCIGCSPLLEYLLDERADRKDIDVRVFGSGSKLDEERAVDIA
KRALEFEPDLVIISTPNAALPGPTKARELIASKGIPTIVIADAPTKKVADKLKEEGFGYI
IVEADSMLGARREFLDPVEMAVYNSDLIKVLAVTGAFNIIYEAVDKAIEAIKKGEKPELP
TIIVNRKAAAKAAKFNNPYAKAKAMAAFEMSKRVADLTTKACFVLKDWEEYTTLCAAAHE
LMRHAARLADEAREIEKYGDYLIRRPHYKDGTIMIKSKLIEKPVKMEEVKSEHESK
>A0A550GEJ1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MALTQNQFKKIGIFKCGNIGTSPLLELLLDELADRKDIKVRTVTTGSKMGAEDVEEALPK
IFELNPDLLIVISPNTALPGPGKVREKISSSGLPGIVISDAPGKRAKEEIEKQGLGYIII
TGDPLIGARKQFLDPIEMAIFNSNISKVLAITGVYRIVQQEIDKAIYAIENGQKPDLPKL
IVDLKAVRDRSEFSNPYAKAKAIAAYGLAEKIAEINVQACFMEKESEKYIPLVTCAHEIA
RTAARLAEEAREIEKCNDTVVRKPHAKDGKLKVKTELMLPPVSDEDFSGNDLP
>A0A550H553|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MTQIQFKKIGIFKCGNIGTSPLLELLLDELADRKDIKVRTVTTGSKMGVEDVEEALPKFF
EFNSDLLIVISPNTALPGPGKVRERMSSSGLPGIVISDAPGKKAKEEIEKQGLGYIIITG
DPLIGARKQFLDPIEMAIFNSNISKVLAITGVYRIVQQEIDKVVYAIENGQKPDLPKIIV
SLKTVRNKSEFSNPYAKAKALAAYGLAEKIAEINVQACFMEKESEKYIPLVACSHEIAQA
AARLAEEA
>A0A371NBR6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermobacter defluvii|TrEMBL
MVVKIGIIRCGNIGTSPVLDLLLDERADRPNIDVCVVGSGAKMNPDEIERAVPTMLEMDR
DFVIFISPNPGAPGPAKARELLSEADVPAMIIGDAPGLRVKDEIEEQGLGYIIVKADPMI
GARREFLDPTEMASFNSDVIKVLAFTGAYRVVQNTIDAMIADVEAGKAPELPQVVIDTDV
AVEAAGYENPYAKAKAMAAYEIATKVADIDVKGCFMVQDPDKYIPIVASAHEMLAAAAKL
AVEAREIEKANDTVLRTPHGKEGETLSKTDLLAKPE
>A0A7C2QI77|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Euryarchaeota archaeon|TrEMBL
MVKLLIIKIGNIATSLVLELLLDERADRKDIEVDVATTGAKMTPDDAKRVLSRVNLDEYN
LIIYISPNPAITGPKMIINALKRRNAIVIGDAPGVKIIQKLEEAQLGYLFILGDSMIGAR
REFLDATEMAIFNAEILKVLSITGALRVVQEEIDKAVDALKKGKKYLPRLVVDTAEAVEA
AGFENPYAKAKAMAAYEAIKLIG
>A0A7L4R2K4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVNNMVAWKP
DFAIVVSPNGVLPGPTGARERLAAAGIPVVFITDDVTTKKEWADIKEGKFGYIIMKGDAM
IGARREFLDPIEMADYNGNLVKVLALTGAFRKLQMALDQVIDQVKAGKKGADLVLPKLVV
TSDKAVDGEFTNPYALAKARAAYEIAQSVAMVNVKGCFMTKEWEKYIPIVSSAHEMMRCA
AVLCDEARELEKAGDGIIRKPHKKDGVIVSKTKLISKPE
>A0A6A2G784|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Methanoperedens sp|TrEMBL
MVVKVGFIKLGNLGTSQVIDLLLDEIAAREGIAVRVFGTGAKMGKDEAAETASFKNWGPN
FVVMISPNSSAPGPTAARDVWKDTPTIVVSDGPTKKEDREKLEQAGFGYIILPVDPLIGA
KREFLDCVEMATFNTDALKVLSICGAIRLVQTEIDKVIDQVAAGTKPLVLPKILAKPDKC
VESAGFNNPYAKAKALAALHIATKVAEIDFPACFVLKEADQVAIAAASGHEAMRAAARLA
DEAREMEKANDSVLRKPHAKDGRLLTKTKLLEKPQ
>A0A7K4B4D3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVSNMKAWGP
DFCIVVSPNGVLPGPKGAREALAAAGIPCVVITDDITSKKDDWEALKASEFGYIIMKGDS
MIGARREFLDPIEMADYNGNLVKVLSVTGAFRKLQVALDEVIDQVKAGKKGKDLALPKIV
MTSDKAVEGEFSNPYAYAKARAAYEIAQAVAGVNVKGCFMTKGFENYTPIVASAHEMMRQ
AMLLCEEAREMEKATDAVIRKPHKNDGTRVAKKTLISKPE
>A0A849QR16|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanophagales archaeon|TrEMBL
MQVVKIGFVKLGNIGASRIVDLLLDERADREDIDARVLGTGAKMTPEHAADTSRLLDWDP
DLVVITSPNAALPGPKRAREMVKEKGKPCIVISDAPAKKAVNDLKENGYGYIIIPGDPMI
GARREFLDPVEMSLFNADVLSVLTITGVVKLLQEELDAVIAAIRKGGDVKLPQIIATVEK
SVERAQFSNPYAKAKAIAAYSMAEKVAELDVKGCFMMKDPKEYVPIVAAAHELLREAAKL
AYEARDMEKQTDSLVRMPHARTGEILKKEKLLEKPSA
>A0A4E0R0I2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanolobus halotolerans|TrEMBL
MAKIGFIKLGNLGMSQVIDLVQDEIAAREGITVRVFGTGPKMGKDEAAATEELKKFDADF
YVMISPNSSAPGPTAARELYKDVPCIVISDGPTKKDDRAALEEAGFGYIIMTVDPLIGAK
TEFLDPVEMASFNSDAMKVLSTCGVVRLIQEELDKVTAMADEGKELELPHILAKPEKCIE
RAGFNNPYAKAKGLAALHMADMVAKINFPACFMMKELEQVALTTAAGHEMMRAAAQMAIE
AREIEKANDSVFRQAHSKKGNLMTKTRLYEKPQ
>A0A0P7ZDL2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Methanoperedens sp. BLZ1|TrEMBL
MVVKVGFIKLGNLGTSQVIDLLLDEIAAREGIAVRVFGTGAKMGKDEAAETASFKNWGPN
FVVMISPNSSAPGPTAARDVWKDTPTIVVSDGPTKKEDREKLEQAGFGYIILPVDPLIGA
KREFLDCVEMATFNTDALKVLSICGAIRLVQTEIDKVIDQVAAGTKPLVLPKILAKPDKC
VESAGFNNPYAKAKALAALHIATKVAEIDFPACFVLKEADQVAIAAASGHEAMRAAARLA
DEAREMEKANDSVLRKPHAKDGRLLTKTKLLEKPQ
>A0A6A8AXE5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|archaeon|TrEMBL
MVKVTILKTGYIGTTTLIDALLDERASRNDISVRVISSGCKMGDDEAVDAAKIAASVPTD
LYIIISPNAGLSGPTKAREIIKETGKPIIVVSDEPSRKAARALPEEGIGYLVLYGDPMIG
AKRDFLDPVEMAIFNADAIKVLAVTGVFRLLHTEIDRVIDEIKRGEEPKLPEVVVNKTKA
LEYSGLNNPYARAKAMAAFEAARRVAVLDVEGCFKTEGRENYMPIIAAAHELMRSAAQLA
DEAREIEKANDSVRRVAHFRSGELREKDGFLEKYRK
>A0A1E7GGS3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp. Ant1|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMGPAEAADTESFKGWNADF
VVIISPNAAAPGPTAAREVWRNVPCIVVSDGPTKKEAREAFEQDGFGYIILPVDPLIGAK
REFLDSVEMSAFNSDAMKVLSVCGVVRLIQEELDKVTEQVASGRSGKELELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKDIEQVCLTAAAGHEIMGAAAQL
ATQAREIEKSNDTVYRQPHAKNGTQLRKTKLYEKPE
>A0A3R9FB50|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanohalophilus sp|TrEMBL
MGNLGMSQVIDLVQDEIAAREGISTRVFGTGPKMDKETAASTDELKAWEPDFVVMISPNA
SAPGPKSARELWNDYPCIVVSDGPTKKDDRQALEDAGFGYIIMTVDPLIGAKTEFLDAVE
MASFNSDAMKVLSTCGVVRLFQEELDAVTAQVDEGKSGADLELPHILAKPQKCIERAGFN
NPYAKAKGLAALHMASKVAEVNMPACFILKEIEDVALTAAAGHELMRAAAQLAIEAREIE
KANDSVFRQPHSKKGAQLQKIKLYEKPQKV
>A0A151BE88|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Bathyarchaeota archaeon (strain B24)|TrEMBL
MVVKVGFAKVGNIATAPLIEFLLDERADRNDIDVRVVSSGAKMGVEQAEEVAKKLLEFKP
DFAVVTSPNATLPGPKRLRELLAEGGIPVIVVSDAPAKKIVKKLQEAGFGYIIVTADAMI
GARREFLDPVEMALFNADLIKVLAVTGVFNIVQVELDKVIDAFKNGEKPTLPRIVIDKDK
AVEAANFSNPYAKAKAMASFEIARRVADLTVEGCFMVKEWERYTLLVAAAHEMMKTAAKL
ADEARELEKATDSVYRSPHSRAGLILSKRKLIEKPAKPV
>A0A7C4XR35|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus sp|TrEMBL
MAKVKVGVLKMGAIGTAVILEYLLDERADREDIEVRVVTSGAKMQPEEAVVAEKLKEFNP
DLIIVASPNAALPGPKAAREAFAGKPVIVISDAPAKKAKDELKEKGFGYIFLNADSMIGA
RREFLDPTEMALFNADVLKVLAATGALRVVQEAIDQGIE
>A0A219AJH2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter sp. 87.7|TrEMBL
MVVKIGIVKSGNIGTSPVLELLLDERADRPNIDVRVFSSGAKMNPEQVEEVVPKVKDFDP
DFCVFISPNPGAPGPAKARELLSEGDIPAFVIGDAPGKGKKDEMDEQGIGYIIVMADPMI
GARREWLDPTEMASFNADVIKVLAATGAYRLVQDTFDKIIADVDAGKDIGLPKLIITADK
AVEAGGFSNPYAKAKAYAAYEICGNLAKLDTKGCFMMKDYKDFLPVVAAAHEMASVAANL
ATEAREIEKSNDTVKRTPHMGDGSTGSKVELISKPE
>B0E8N0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Entamoeba dispar (strain ATCC PRA-260 / SAW760)|TrEMBL
MSTKNKNTKISKILDQIDIDQLKVLIDEVGVVVLQIKNYGTLNIGNPEFDESSQEDSESS
YTTSESDSSYSSEESSYSSESDDEELPVQQEQEKINPPNSVNNDKIIQSQNKGSDTKNIT
KEEINKNEKEKTKKFEEEQLKKAQEVIQKKVNACSVPKKVLRVEEIDEDDDVFTKNESET
LKAAEYVAQTKQLQNGTNNPVIDKELAMGYLYVNNNRVKEAVDYFTVFLKKYPNVVGAFL
GRGTALAMLSNFEKAIQDFTSAIKCDPKCGDAYKRRGQTLVACGKLYEGLEDFNKAIELS
NGKDGDCYAQRGSVYQMLKNYEKGRADFREAVRKNSMDFNSWNHLGLNNNALGLVAEAAD
AYARALQIKDDFIECYVNLAQLHKDAGNFQRSKDVFNKLFRMQPNHSNGHYICGVLYQQS
GYHLAAIKEFTLAIDNRTEPISGIEKDPERMCEAWRYRGVTRSASGQFRLAVEDFERAME
LKSDDTAWYMKEIALYTHHHLNKSFEEWDLESFYPFFKEGFCKHLIPAALHRYEEQPPFE
ESISDVDEKSLPSQNVINRIIIPAMNIGKYMQYDSQGFVHNKAQYLMAGMAAIEMAKKIR
DVLPEWVFGGLTEEQAKPYIGKLHWRDVMKIAVKWRQISEPNDPVYWIDLLTHEQFEEGF
GSHTPMFIGQTRVVRYYCQYQRAFEIVKKLLPEQLKIKEDWAEKVKAAKNIQDILDVMKS
DFHVTTPCKSLYFDDPDKPGTKRTYEGTRLVVEIKQPGYEFAIKTPCTMPRWKLYDEELT
ECWKNIVRLVLTRKGKKGEDEALLRAMFDFTFYWYNFMPLSRGTAATGFVFMLAMLASLN
YQINKHIPKGMQTDWEAILCDEPKKFEDVMMGWMKDSITQFDVESVPDFKRVLPNVRSII
ECFNYCPQVKCE
>A0A8J8K6B0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Asgard group archaeon|TrEMBL
MVKITFVKIGNITLTTLVDIMLDERASRTDIDATVISSSTKMKPEAAERLFPLIDQVETD
LLVMISPNANDKGPQSVIDKYKEKYPVIVVSDAADKEMRAKWKEEGVGYIIAPFDPMIGA
KLDFLDPTEMCLFNGYIITAFSATGVFAYITKLFDDVIGQLKTGSKPELPNNYLSSIGIV
TSYPFTNEYSRPKAMAALNILNEAGKLNVNGCFVEKDKDRQLIKVAAAHEMVRQASFLAD
EVRELEKAVNHLVRTPHNKEGKILHKAHFFDKAHEKQ
>A0A843JDP2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobium sp|TrEMBL
MVVKVGIAKLGNIASGVMGELLLDERADREDMQTFMATSGTKLQPEDIERVVSNMKAWGP
DFCIVVSPNGVLPGPKGAREELAAAGIPCIVITDDITTKKDDFAALKESSFGYIIMKADS
MIGARREFLDPVEMADYNGNLVKVLTITGAFRKMQLAIDAVIDQVKAGKKGAALELPKIV
MTSDKAVEGEFTNPYAYAKARAAYEIAQAVAGVNVKGCFMTKGHENYTPIVASAHEMMRA
AMVLCDEARELEKGCDGVIRKPHKADGVIVEKKELISKPW
>A0A2P0QMK8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured bacterium|TrEMBL
MEKRSILHMLDPMPNNSPFDINMAMDAGFDVLMPYSNVKLDSVNRLTQDAIFSRSPAGVK
RTGIFIGGRDLGLAIDMLDASKQAMVPPFEVSVFADPSGAFTTAAALVACVEKELKSKHG
KELKDCNALVFGGTGPVGIATGIIASLAGADTALVDHLSIEAASDVAKDYNRRFGCSLKG
ACASSDADKIQLVANADIVFCVAKAGVQVLSSAVLKEAKQLKVAGDVNAVPPMGIEGIKR
NDLGAPLIHALSSQGAVGVGALAVGNVKYQLQH
>A0A842KK08|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomethylovorans sp|TrEMBL
MAKIGIIKLGNLGMSQVIDLVQDEIAAREGISIRVFGTGPKMGKDEAAATADFKKIGADF
YVMISPNSSAPGPTAAREFYKDVPCIIVSDGPTKKEDRDALEQAGFGYIIMTVDPLIGAK
TEFLDAVEMASFNSDAMKVLSTCGVVRLIQEELDKVAAQVDAGEPIQLPHILAKPEVCIE
RAHFNNPYAKAKALAALHMADMVAKINFPACFMMKELEQIALTTAAGHEMMRAAAQLAIE
AREIEKVNDSVFRQPHSKKGGKVFQKTKLYEKPQ
>I7LMX2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoculleus bourgensis (strain ATCC 43281 / DSM 3045 / OCM 15 / MS2)|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMITFMATSGTKLQPEDIDRVVSNMKAWAP
DFCIVVSPNGVLPGPTQAREDLAAAGIPCIVITDDVTTKKDQFAALKESDFGYIIMKADA
MIGARREFLDPIEMADYNGNLVKVLAITGAYRKMQLELDKVIDQVKAGKKGKDLVLPKVV
MTSDKAVDGEFSNPYALAKARAAYEIAQQVAAVNVKGCFMTKEWEKYIPIVASAHEMMRQ
AMILCEEARDLEKGMDAVIRKPHKKTGEIVSKTKLISKPE
>A0A843D6T8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter sp|TrEMBL
MVVKIAIIKSGNIGTSPVIDLLLDERADRPNIDVRVFGSGAKMNPEQVEDVVPKIDAFEP
DFAIFISPNPGAPGPAKARELLSEKDLPAIIIGDAPGKGKKDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNADILKVLAETGALRLVQKTIDGVIAAADAGEEIELPKLIITAEK
AVEAAEFANPYAKAKAIAAYEMAGSVANLDMKGCFMTKGFENFIPLVAAAHEIAAAAAKL
AQEAREIEKSNDTVLRTPHMKEGNPGRKTDLISKPE
>A0A3N5MRE5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoregulaceae archaeon|TrEMBL
IELPKIIMTTDKAVDGEFTNPFALAKARAAHEIAIAVAGQNVKGCFMTKEWEKYIPIVAS
AHEMMRSAAMLCDEARELEKAGDSILRQAHKKDGTLVAKKKLVAKFE
>A0A0A8RV90|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Propionibacterium freudenreichii|TrEMBL
MDTTENRVPVQIGIFSVSDLTPDPTTGITPTEHERLKNYALIVKKAEEIGLDAFALGEHH
NPPFVSSSPTTTLGWLAAQTSKITLSTATTLITTDDPVKIAEDYAMLQHLADGRVDLMLG
RGNTGPVYPWFGKDIRQGINLALENYNLLHRLWREEVVDWQGKFRTPLQGFTAIPRPLDD
VPPFVWHGSIRSPEIAEQAAYYGDGFFHNNIFWMMNHTKRMVDLYRRRYEHYGHGRYDQA
IVGLGGQFFMRKNSQDAIKEYRPYFDNAPVYGHGPSMEEFTEYTPLTVGSPQQVLERTLS
FKDDVGHYQRQMFLIDHAGLPIKTVLEQLDLLGEILPEMRKGFLEGRPDDIPDAPTHASL
VAARDAAGVAPVEHVKVGADDVTGTSDAPEPPDSVFEK
>A0A2U1S6A9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter woesei|TrEMBL
MVVKIGIIKSGNIGTSPVLDLLLDERADRPNIDVRIVGSGAKMNPEQTEEVVPKIKDFDP
DFCIFISPNPGAPGPAKARELLSEMDVPAIIIGDAPGAGKKDEMDEQGLGYIIVKADPMI
GARRELLDPTEMACFNSDIIKVLAATGAYRLVQNTIDEVIASCEAGDIELPKLIITAEKA
VDAANFANPYAKAKAIAAYEMAAAVADLDLKGCFMLKDHNQYIPIVAAAHEMAAAAAKLA
VEARDIEKSNDTVTRTPHMGDGSTGSKSVLLEKPQ
>D1YY63|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocella paludicola (strain DSM 17711 / JCM 13418 / NBRC 101707 / SANAE)|TrEMBL
MTARVGIVKLGNLGTSRYIDLILDERADRDIYVRTVGTGAKLGEAEADEAVAKILEFKPQ
LCIVISPNGALPGPTKAREAIKAAGVPTIAISDVPMMKVKDDLKAKGLGYFIVKCDSMIG
ARRQFLDPTEMVLFNADMTKVLAETGVVRLIQTELDKCIDMINAGQPVTVPQIVIDAAKA
VPMAGYTNPYAQAKAFAAFAAAEKVGDLDLLGCFMQKEMEQYIITVASAHELLRTAALLC
DQARELEKGGNSIKRTPHAADGKVLSKTTLVSKPE
>N6VTP4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocaldococcus villosus KIN24-T80|TrEMBL
MIKIAIIKCGNIGMSPMIDLSLDERADREDIIIRVFGSGPKMDPESVEEVTKKAIEENPN
LIIYIGPNPSAPGPKKAIELLKECKIPSIIIGDAPGIKIKDKIAEAGLGYIIVKCDSMIG
ARREFLDPTEVGFFNSDIIKVLAGTGALRAVQMAIDKVISEIKEGKEPELPKLIIDEEKA
VEAMEFTNPYAKAKAMAAFVIAEKVGDIDVKGCFMVKEAEKYIPIVASAHEMLRYAAKLI
DEARELEKANDAVSRKPHARDGRVLSKKRLMEKPQ
>A0A7J4DNA2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Nitrososphaerales archaeon|TrEMBL
MPVNITVVKTGFIGVTTLIEVLLDERASRKDISVRSITSGSKMSITDTQEVEKLSSSLDT
DLYIVVSPNASLDAPKNLALNLGKIKPTILISDSPASKIKDELVDKIGYIFVQGDPLIGI
HKEFLDPIEMSNFNSDVLKVLSITGAFQALINEIDKVIEQIKTSQPIVLPKLVIGKHTAV
SNSGLTNPYSKAKALASYEIARLVAKLSAEGAYKERDRERRLLTVSASHELIRQAAKLAD
EAREIEKHSDSVNRYIHATTGKTLTKKKFFDSV
>A0A843KSM8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoculleus sp|TrEMBL
MVVKVGIAKLGNIASGVMGELLLDERADREDMITFMATSGTKLQPEDIDRVVSNMKAWGP
DFCIVVSPNGILPGPTKAREDLAAAGIPCIVITDDVTTKKEQFEALKASNFGYIIMKADA
MIGARREFLDPIEMADYNGNLVKVLAITGAFRKMQLELDKVIDQVKAGKKGADLALPKVV
MTSDKAVEGEFSNPYALAKARAAYEIAQSVAGVNVKGCFMTKEWEKYIPIVSSAHEMMRQ
AMYLCEEARELEKAMDGVIRKPHKKTGEIVSKTKLISKPE
>A0A7T9HGN5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanolinea sp|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVNNMVAWKP
DFAIVVSPNGVLPGPTGARERLAAAGIPVVFITDDVTTKKEWADIKEGKFGYIIMKGDAM
IGARREFLDPIEMADYNGNLVKVLALTGAFRKLQMALDKVIDQVKAGKKGAELVLPKVVV
SSDKAVEGEFTNPYALAKARAAYEIASAVAMVNVKGCFMTKEWEKYIPIVTSAHEMMRCA
AVLCDEARELEKAADGIIRKPHKKDGVIVSKTKLISKPE
>A0A523AMA1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Hadesarchaea archaeon|TrEMBL
MSRKVRIGVVKVGNIGTSPMIDLLLDERAEREDVDFRVVGSGPKMQEEECKECAQKILEF
NPDLVLIVSPNPALPGPTAARRIVAGAGKPVVVVGDAPGKKAVPDLEKEGMGYLLIEADA
MIGARREFLDPAEMALFNANVIKVLAATGAFNVVCEEVEKAIQGIKGGSPYLPRVVVTRQ
KAVEAAGFQNPYALAKAMAAYEMAKKVAELSVEGCFKLKEMKEYVPVVASSHEMMEAAAR
LASEARELEKPTDSLLRKPHADDGRLLSKRKLMEKPS
>A0A7J2ZD12|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKKVKIGIFKCGNIGTAPLLELLFDELADREDISVRTITTGAKMLAEEVSEALPKIFDFN
PDFIIFISPNPAVQGPRKAMEILSEKKIPSIFISDAPGKRLKEEFEKQGFGYIIVMGDPL
IGARKEFLDPTEMAIFNSNVIKVLAVTGVYKMIYQEIDRVIHCCKEEMAFELPRLIIDTD
NIRDSSDFRNPYALAKAMAAYELTKKIAEINTRACFMEKEKEKYIPLVACAHEIAQVAAS
LAEEAREIEKYADTLVRRPHSKEGRLKVKDKLMLPPILDEEIYQKWLKMLKAGEF
>A0A7C4R5S9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVKVGVLKAGCLGSLPLLEFLLDERAEREDISVRVVGSGAKVTVDECIECAKEILSQNPD
FIILIGPAQTTSGPTEARKVLREAGKPVIVISDTPAKRIVKDLEESGFGYIIVEADSMIG
ARREFLDPSEMALYNSDVIRVLAITGALNVIVEEIDKVISAIKSGVKPVLPRLVLDSKII
AERSGFLNPYARAKAIAAYEMAKQVSAITIEACFKIHDPEVYIPLVAAAHELMRFAARLA
DEAREIEKGGDTILRKPHFRDGLIGEKRNLMEKPARVSS
>A0A497JNB1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MRVGVVKCGNIGTAPLFELLLDELADREDIAVRSITTGSKMMAEAVEEALTSMFEFSPNL
IIFISPNPAVQGPKRAREILSEKNIPCIFISDAPGKRLREEFEKLGFGYIVVMGDPLIGA
RKEFLDPTEMALFNSNMIKVLAITGVYNIILREIDRIIHNLKENLIVELPKLVIDTGEVR
DKSDFKNPYAKAKAMAAYELTKKIAEINTKACFIEKEKEKYIPLVACAHEIAQAAARLAE
EAREIEKYSDVLTRRPHARNGKPKIKERLMEKPTFDEETYQEWFK
>A0A497LTB8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVRVTFLKIGFLGVSNLIEALLDERASRRNLSVRVVSTGCKMDEDEAVEAAKLAASIRSD
LYVVVSPNAALPGPKAARELLKETGKPIIVVSDEPTKKIADSLEEEGFGYILIYADSMIG
ARREFLDPVEMALFNSDVLRVLAVTGALRLVQMELDRVIRLIEAGEQPELPRVRITKERA
LEMSGLNNPYAYAKAMASFEMARRVAALSTEGCFKVKERDRYIPIVAAAHELMRWAAMLA
DEAREVEKANDSVTRIVHFRDGSLRRKRKLYEKFEPLIDL
>A0A550GW18|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MGVEYQSLVKELVTVTFVKIGYIGTTIIIEALLDERSARTDLKMRTVACGVSMDEADAAE
VSKIAAGIESDLYIVVSPNAALPGPKKAREILKETGKPIIAISDEPSRKAMKELPAEGMG
YIVVYGDPMIGAVTAFLDPIEMAIFNGDVLKVLSVTGIFRLIQSEIDRVIDEIKEGKKPV
LPEIVITKLTALQHSGLVNPYAYAKGLAAFEMSRNVADLTTEGVFKTEDRLEIIQKVAAA
HELIRQAAKLSDEAREIEKANDSVERIAHFKGGDRRKKTELYGKHEK
>A0A497NZ91|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKIGFAKVGNIACSPLLEFIFDERAERKDIEVRSFGSGSKIDLNSCVSIADEVVKYKPDL
IVLSTPNAALPGPKKAMEIFKETKIPTVTVSDNPAKKATKTMEEAGIGYIIVEGDVMIGA
RKEFLDPTEMACFNSDIIKILAVSGAFEVVRIEISKLIETIKKKESPELPKVTVTRSKAV
NSASFTNPYAKAKAASAYEMARRAGELNFQGCFIEKDWEKYVQLVTSGHEIIRAAARLAD
EAREIEKYSDTLARKP
>A0A147JSR5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Hadesarchaea archaeon DG-33|TrEMBL
MAKRVRVGLVKMGNLGTSAMLDLMLDERAEREGIDFRVVASGPKITEEDCEGVSKKILDF
NPELIIAISPNPALPGPSKAREILKKSGKPCIIIGDAPGAKIAGELEKTGFGYIFVEADS
MLGARMEFLDPVEMSLFNADVIKVLSVTGASRVVYEETDKAIEGVKSGKPYLPRIIVDRD
KAVGAAKFENPYARAKAMAAFEIAKKVADVSVEGCFRVKEKERYIPIVAAAHEMMRTAAK
LCDEAREIEKSEDSVLRRPHGRKGELLSKRKLMENEN
>A0A7J9RLR7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanophagales archaeon|TrEMBL
MDVVKVGFMKLGNIGTSIIASLLLDERAEREDIDVRALGTGAKMSPECALDTALLLDWGP
DVVIVSSPNAA
>A0A510BD41|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanofervidicoccus sp. A16|TrEMBL
MVVKIGIIRCGNIGTSPLIDLILDERADRKDIDVRVLGSGAKMGVEQVEEVTKKMIEDIK
PDLIVFISPNPAAPGPKKARELLSKCDIPSVIVGDAPGLKVKEDIEKEGLGYIIVKCDPM
IGARREFLDPVEMVLFNADVLKVLAGTGAIRVVQHAIDSMIDAIKEGKEVELPKIVVNES
RAIESMEYTNPYAKAKVMAAFKIAEMVGDINVKGCFIVKEREKYISVVASAHEMIRYAAK
LVEEAREMEKALDTVSRKPHGSDGRILSKNKLLEKPE
>D5EAK3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP)|TrEMBL
MVKVGFIKLGNLGMSQVIDLVQDEIAAREGITTRVFGTGPKMDKETAASTEELKAWDPDF
VVMISPNASAPGPKSARELWKDYPCIVVSDGPTKKDDRQALEDAGFGYIIMTVDPLIGAK
TEFLDAVEMASFNSDAMKVLSTCGVVRLLQEELDAVTAQVDEGKSGADLELPHILAKPQK
CIERAGFNNPYAKAKGLAALHMASKVAEVNMPACFILKEIEDVTLTAATGHELMRAASQL
AIEAREIEKANDSVFRQPHSKKGFQLQKTKLYEKPQKV
>A0A5C9ETY0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MSENVLNIGVLKNGTIGSSVLLSFLIDERAEGERVIFREVTSGPKMHPPEECVETMKKLL
EFQPDLILMSSPNAALKGPKAARELVGDIPAIIISDAPAKKAIEEFKEKGLGYIIVECDS
MIGARRPFLDPIEMSVFNSNLLKVLAVTGVFNIIVDELNTVIMDMLEGKTPTLPQIEVDA
TTAVEAARFANPYAEAKAIAAFEIASKVSKITGKACFVLKEREDYMPLLAAAHEMMKTAA
DMCQVAREIEKSNDTVIRRPHRSSQELLEKRALHEKEK
>A0A842WU04|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MINIGILKFGCIGATPLLEMIIDERADREDISVKVIGTGSSMKPEACEAATSQMIQERPD
LVIIVSPNAALKGPKLARKLLEKSTITTLTISDAPASKAFYKKNEEGQKEPYTLVNQGFI
IITADSMIGARREFLDPTEMVMYNADVLKVLAATGVFRALHEIIDSMIEGIKINKVLLPT
KKITEDVVYEYGGYENPYAEAKAYAAFRMAKEVSGITTRACFRESDSKRYIPLVAAGHEL
MRSAALLVDEAREIEKSRDSVLRTSHKSDGKISERKELGK
>A0A7K4D648|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothrix sp|TrEMBL
MFKIGFVKLGNIATSTAIDLALDEIAERTDLESKIISFGPKMTKKEGEASAELKAWGPQL
VVISSPNAATPGPTSAREQFKGLPVIVISDGPTKKEARDALAAEGFGYIILPVDPLIGAK
REFLDPSEMALFNSDALKVLAACGAIRLVQEELDKAMMAIASGEPKLPRILATPEKCAER
MNFYNPYARAKAVAALYMAQTVATIDATACFRLKELEAIALTAAAGHEVMRAAGRLADES
REMEKANDSVSRKPHARTGELMVKTKLMEKPGKI
>A0A0E3KRG2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina thermophila CHTI-55|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFSTGAKMSPAEAADTENFKQWNPDF
VVIISPNAAAPGPTAAREIWKDVPCIVVSDGPTKKEAREALEQEGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLIQEELDKVTDQVASGKSGKELELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
AMQAREIEKSNDTVFRQPHAKNGALLKKVKLYEKPQ
>A0A7J9SPM9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|ANME-2 cluster archaeon|TrEMBL
MAKVGFIKLGNLGMSQVVDLILDEIAARKGIEVMSFGTGAKMGKEEAAKTKHFKEFEADF
YVMISPNSSAPGPTAAREIWKDKKVIVISDGPTKKDDRKALEDAGFGYIIMKVDPLIGAK
TEFLDPVEMASFNSDAMKVLSTCGVVRLIQEAFDAVIAQADAGKDLELPHLLVSAQKAVE
SAGFNNPYAKAKALAALHMTDKVAEINFPACFMMKDIEQVTLTTATGHEMMRAAAQLAID
AREIEKGNDAVFRQPHMKDGSLKTKTKLYEKPQ
>A0A7C4HK90|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVKVGFAKIGNIGSAPMIEFLLDERADRNDIDVRVVSSGAKMGVEQAEEVAARLLEFKPD
VVIVTSPNASLPGPTRLREQLAEKNIPVVVVSDAPTKKIVKDLQSRGFGYIIVMADSMLG
ARREFLDPVEMALFNSDLIKVLAITGVFNIIQVELDKIIDALKQGVKPTLPAVVITKDNA
VEAAKFSNPYAKAKAIASFEIARVVADLTVEGCFIVKEWEHYTTIVAAAHEMMKYAAKLA
DEARELEKANDSVYRSPHSRTGAILAKRKLIEKPTEQVQ
>A0A842RN40|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MSEDNLKIGVLKNGTIGSSVLLSFLIDERAEGKRVVFREVTSGPKMHPPEECVETMKKLL
EFEPQLILMSSPNAALKGPKAARELVGDIPTIVISDAPAKKAVDEFKEKGMGYIIVGCDS
MIGARRPFLDPIEMSLFNSNLLKVLAVTGAFNIIVDELNKVIMDMLEGKQLTLPQIIVDS
TTAVKAARFGNPYAEAKAIAAFELAAQVSKITGKACFVLKEREEYMPLLAASHEMMKTAA
DLCQTAREIEKSNDTVIRRPHKSNQVLLEKRALHEKEK
>A0A124F8C8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus fulgidus|TrEMBL
MVKVGVLKMGAIGTALLVEYLLDERADREDIEVRVVTSGAKMQPEEAVVAEKLKEFDPDV
VIVVSPNAALPGPKAAREAFEGKPVIVISDAPAKKAKDELKEKGFGYILINADSMIGARR
EFLDPTEMALFNADVVKVLAATGAFRLVQEAIDKVIEDIKAGKQPELPQIVVTAEKAVEA
GKFSNPYAKAKAMAAFYIAEKVADIDVKGCFIEKDPEKYIPLVASAHEMMRIAAILADQA
REIEKSNDTVFRNPHAKDGKILGKTQLMAKPE
>M1PWC9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina mazei Tuc01|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMAPADAADTESFKQWNADF
VVIISPNAAAPGPTAAREIWKDVPCIIVSDGPTKKEAREAFEQEGFGYIILPVDPLIGAK
REFLDSVEMASFNADAMKVLSICGVVRLIQEELDKVTEQVASGKSGKDLELPHIFAKPEK
CVEHAGFANPYAKSKALAALHMAEKVAQVNFPACFMLKEIEQVCLTAAAGHEIMGAAAQL
ANQAREIEKSNDTVSRMPHAKNGAVLKKVRLYEKPE
>A0A520JU80|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MVKVGFVKMGNIGTSLVIDLLFDEIAEREDINTRTFSSGAKMGKEEAADTKHFKRWHPDL
LVMVSPNPGAKGPVEARRIWKDVPTIIISDGPTKKDERQKLTDAGFGYIILPVDPLIGAK
REYLDTVEMVNFNSEVNKTLAFTGAIRLVQETIDGVIEEIKASKTLNLPNILANPEKCIE
YGGFSNPYAKAKALAALHVLLKAAEINSRACFGMKGIEAITLTTAAGHEMVRIASMLVDE
AREIEKCNDTVSRKPHARDGRILSKSKLYEKPE
>A0A2D8MMH6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thaumarchaeota archaeon|TrEMBL
MVLNITVVKTGFLAVTTLIEALLDERASRKDISIRSVSSGAKMNKVDIDAVEQLAKSIDT
DLFIVVSPNASLDGPKNLALNLGKLKPTILISDNPATKIIEELKGKIGYIIIQADPLIGI
RKEFLDPIEMSNFNSDVIKVLSITGAFSALIHALDSFINESTNGNANLPNIIIDKHQALE
HSGLSNPYAKSKALASYEMARLVGRLSAEGGYKEKDREKYLLVVSASHELIRQAAKLADE
ARELEKENDTVHRNIHDSSGKTLTKKKFFDTL
>A0A3M9LNW2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanohalophilus sp. RSK|TrEMBL
MVKVGFIKLGNLGMSQVIDLVQDEIAAREGISTRVFGTGPKMDKEKAASTEELKAWEPDF
VVMISPNASAPGPKSARELWNDYPCIVVSDGPTKKDDRQALKDAGFGYIIMTVDPLIGAK
TEFLDAVEMASFNSDAMKVLSTCGVVRLLQEELDAVTAQVDEGKSGADLELPHILAKPQK
CIERAGFNNPYAKAKGLAALHMASKVAEVNMPACFILKEIEDIALTAATGHELMRAAAQL
AIEAREIEKANDSVFRQPHSKKGVQLQKTKLYEKPQKV
>A0A2I0PJG5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacteriales archaeon HGW-Methanobacteriales-1|TrEMBL
MVVKIGIIKCGNIGTSPVLDLLLDERADRPNIDVCVIGSGAKMNPEEIEKAVPLMLEMER
DFVIFISPNPGAPGPAKARELLSAADVPAIIIGDAPGLRSKEEMDEQGLGYIIVKADPMI
GARREFLDPTEMASFNADVIKVLALTGAYRVVQNTIDAAVNAVEAGSAIELPKVVISRDV
AVAAAQFASPYAKAKAMAAYDIATKVADIDVEGCFMTRDAEKYIPIVASAHEMITTAAKL
AAEAREIEKANDTVVRTPHGGKGQTMAKSVLMEKPQ
>A0A1I0BY97|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcoides vulcani|TrEMBL
MAKIGFIKLGNLGMSQVIDLVQDEIAAREGISIRVFGTGPKMGKAEAAETEAFKEWGADF
YVMISPNSSAPGPTAARELYKDVPCIVISDGPTKKDDRQALQDAGFGYIVMTVDPLIGAK
TEFLDAVEMASFNSDAMKVLSTCGVVRMIQEELDAVAAQVDEGKSGKDLELPHILAKPEK
CIERAGFNNPYAKAKALAALHMADKVAQINFPACFMMKEIEQVTLTTATGHEMMRAAAQL
AIDAREIEKANDSVFRQAHSKKGVLMTKTALYEKPQ
>A0A0L0MIB1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Burkholderia verschuerenii|TrEMBL
MPEASDRPYVLHMFTSTPQMSPFDVNMAADAGYQILVPYCNVDEDSVVTLTQDAIFSRGP
KGVSRTGIFIGGRDVMQAADMLERARHAMVPPFEVSVFTDPSGAYTTAAALVALAEKHLK
AIHQLEFDGKRVLILGSTGAVGRVAAAMAASLGAVVAVASHSSQSRATQVSDEINRRFDI
ATSGVATGSPEQLHRELARAEIVFATAVAGVQVMTAADLSHAKNLLIAADVNAVPPEGIA
GVNVMDDGKPLAGAARSDAIGIGALAIGNVKYQTQHRLFVRMRTGGKPVYLGFPEAFDEA
RAVVAGQGS
>A0A520K8D3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanophagales archaeon ANME-1-THS|TrEMBL
MVVKIGFVKLGNIGTSRIVDLLLDERADREDIDVRVLGTGAKLTPESAPDTARLLDWNPD
FVVVSSPNAALPGPKQAREMVKAKGKPCIVISDAPAKKAVDELKEKGFGYIIIPGDPMIG
ARREFLDPVEMSLFNVDVLAVLSITGVARMVQEELDSVIDQIKKGGAVKVPQIVVTAENA
VERARFSNPYAKAKAIAAYNMAERVADMDVKGCFMLKNPEEYIPMVAAAHELISEAARLA
KEAREIEKQSDSLVRMPHAKTGEVRKKTKLMEKPGA
>A0A832YVQ6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus profundus|TrEMBL
MVKVGIFKMGAIGTAILLEYLLDERADREDIEVRVITTGSKMREGDAKVGEKLKDFNPDL
IIIVSPNASLPGPKIARELFGDKPVIVISDAPARKIVNELERERFGYILITADSMIGARR
EFLDPTEMALYNSYILNVLAITGALRLVQEEIDKVIAQIKEGKKIELPRIIVTADKAVEA
GRFSNPYAKAKAMASYYIAEKVADITTKACFIEKDAKKYIPMVCAAHEMMRIASKLAEEA
REIEKGNDSVFRNPHAKDGEILSKIKLMDKPT
>A0A842L4G7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacteriales archaeon|TrEMBL
MVAKIGVLKCGNLGTSPVIDLVLDERADRPNVEIRVMGSGTKMNPEDIEFVVPKMLELDR
DFIIFISPNPGAPGPARARELLSEADVPAMIVGDAPGLRVKDEIEEQGLGYIIVKADSMI
GARREFLDPTEMAAFNADLMKVLALTGAYRVVHNTIDAMIADVEAGKEIELPQLVITRDV
AVEAADFQNPYAKAKAMAAYEIATKVADIDVEGCFMVQDPEKYIPIVASAHEMMSTAAKL
AEEAREIEKSNDTVRRTPHGKEGETLSKEKLLEKPS
>A0A7J9TFT5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|ANME-2 cluster archaeon|TrEMBL
MAKVGFIKLGNLGMSQVVDLILDEIAARK
>A0A842L9B9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacteriales archaeon|TrEMBL
MVAKIGVLKCGNLGTSPVIDLVLDERADRPNVEIRVMGSGTKMNPDDIEFVVPKMLELDR
DFVIFISPNPGAPGPARARELLSEADVPAMIVGDAPGLRVKDEIEEQGLGYIIVKADSMI
GARREFLDPTEMAAFNADLMKVLALTGAYRVVHNTIDAMIADVEAGKEIELPQLVITRDV
AVEAADFKNPYAKAKAMAAYEIASKVADIDVEGCFMVQDPEKYIPIVASAHEMMSTAARL
AEEAREIEKSNDTVKRTPHGKEGETLSKEKLLEKPS
>J0RY20|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanofollis liminatans DSM 4140|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVTNMKAWGP
DFCVVVSPNGVLPGPTGAREELAKAGIPVVVITDDITTKKEQFDALKASTFGYIIMKADS
MIGARREFLDPIEMADYNGNLVKVLALTGAFRKLQFELDKVIDQVKAGKKGADLVLPKVV
MTSDKAVEGEFSNPYALAKARAAYEIASAVAGVNVKGCFMTKEWEKYIPIVCSAHEMMRQ
ASVLCDEAREIEKAGDAVIRKPHKKDGVIVSKTALISKPE
>A0A832X0J5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMSPAEAADTESFKQWNADF
VVIISPNAAAPGPAAAREIWKDVPCIVVSDGPTKKEAREAFEQEGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSTCGVVRLIQEELDKVAEQVASGKSGKNLELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
AIQAREIEKSNDTVFRQPHAKNGTLLKKVKLYEKPE
>A0A0E3WTL1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina horonobensis HB-1 = JCM 15518|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMGPADAADTESFKQWNADF
VVIISPNAAAPGPTAAREIWKDVPCIVVSDGPTKKEAREAFEQEGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSICGVVRLIQEELDKVTEQVASGKSGKDLELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
ATQAREIEKSNDTVFRQPHAKSGALLKKVRLYEKPE
>A0A832QMA6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermobacter sp|TrEMBL
MVAKIGVLKCGNLGTSPVIDLVLDERADRPNVEIRVMGSGTKMNPEDIEFVVPKMLELDR
DFVIFISPNPGAPGPARARELLSEADVPAMIVGDAPGLRVKDEIEEQGLGYIIVKADSMI
GARREFLDPTEMAAFNADLMKVLALTGAYRVVHNTIDAMIADVEAGKEIELPQLVITRDV
AVEAADFKNPYAKAKAMAAYEIATKVADIDVEGCFMVQDPEKYIPIVASAHEMMSTAAKL
AEEAREIEKSNDTVKRTPHGKEGETLSKEKLLEKPS
>A0A0U3EKN6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter millerae|TrEMBL
MVVKIGIVKSGNIGVSPVLDLLLDERADRPNIDVRVFGSGAKMNPEQVEDVVPKVEQFDP
DFCIFISPNPGAPGPAKARELLSAMDKPAVIIGDAPGKSKTEEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNSDILKVLAETGALRLVQNTIDDIINAFDNGDEIELPKLIITAEK
AVDVAGFENPYAKAKAIAAYEMAGAVANLDMKGCFMTKGYENFIPLVAAAHEMASCAAKL
ASEAREIEKSNDTVLRTPHMKEGQTGSKKDLISKPE
>K6U983|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium sp. Maddingley MBC34|TrEMBL
MVVKIGVIKCGNIGTSPVLDLVLDERADRPNIDVRGVSSGAKMNPEQIEEVVPKIMDYEP
DFVIFISPNPGAPGPAKARELLSGMDVPALIIGDAPGMGKREEMDEQELGYIVVLGDPMI
GARREFLDPTEMASFNADVIKVLAATGAYRVVQETIDGMIAAAEAGETIELPKVVIDAAK
ATETAGFSSPYAKAKAMAAYEMAAKVGDIDLKGCFMVKDMEKYVPIVASAHELIATAAKL
ATEAREIEKANDTVLRKPHGPQGQTMSKTVLVSKPE
>A0A849PZ14|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcoides sp|TrEMBL
MAKIGFIKLGNLGMSQVIDLVQDEIAAREGISVRVFGTGPKMGKDEAAETAALKEWDADF
YVMISPNSSAPGPTAAREIYKDVPCIVISDGPTKKDDRQALEDAGFGYIIMTVDPLIGAK
REFLDSVEMASFNADAMKVLSTCGVVRLIQEELDIVTAQVDEGKEIVLPHILAKPEKCIE
RAGFSNPYAKAKALAALHMADKVAQINFPACFMMKEIEQVTLTTATAHEMMRAAAQLAID
AREIEKSNDTVLRQPHAKKGNILSKTALYEKQQ
>A0A328SCW4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosphaera sp. rholeuAM74|TrEMBL
MVVKIAIVKIGNIGTSPVIDLVLDERADRNDVEVRTISSGSKMGSKQVEDLLPNIHKLNP
DIIIFISPNPNAKHPKRAREILSEIDIPTIIIGDKPGEKAIGQMKEQNLGYILIRADPMI
GARREFLDPTEMALFNSDVLKVLSITGAFRLVHETMDELINKLNNNEEIELPEIVVKAEV
AIQYAGFKNPYAMSKALAAYHIASRVSDMDIKACFKTDEPDIYIPLVTAAHEMMSAAAKL
ADEARDIEKGNDTVLRTPHRRDGTVLRKTSLMDNFD
>A0A7C2NB30|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus fulgidus|TrEMBL
MVKVGILKMGAIGTALLVEYLLDERADREDIEVRVVTSGAKMQPEEAVVAEKLKEFDPDL
VIVVSPNAALPGPKAAREAFEGKPVIVISDAPAKKAKDELKEKGFGYIFINADSMIGARR
EFLDPTEMALFNADVVKVLAATGAFRIVQEAIDKVIEDIKAGKQPELPQIVVTAEKAVEA
GKFSNPYAKAKAMAAFYIAEKVADIDVKGCFIEKXPEKYIPLVASAHEMMRVAAILADEA
REIEKGXDTVYRNPHARDGKXLSKTQLMTKPE
>A0A7C5K2J8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Methanoperedenaceae archaeon|TrEMBL
MVKVGFIKMGNIGTSIVIDLLFDEIAQ
>A0A7J2T8G9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
ELTKKVAEINTKACFIEKEKEKYIPLVVCAHEIAQVAAKLAEEAREIEKYSDTLVRKPHS
KDGRLKVKEKLMMPLVFDETIY
>A0A7J3NRP3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MDVVKVCVVKTGNIGSAPLLELLLDERADRGDIDVRVISSGAKLNPEQAEEVAEKALDFK
PDLVLVVSPNAALPGPSKVREVMAKAGVPTIVITDAPGKKAREDIEGKNQGYIIVNADAM
IGARREFLDPVEMAIFNADIIRVLAITGAFTVIYREIDKVIESIKKGATPELPRIIVDKE
TAVEAMGFSNPYAKAKAIAAYEAASKVADLTVEGCFKIQEFEKYVPIVAAAHELMKQVAR
LADEARELEKSGDAVLRMPHKKSGEIVSKRKLLEKPS
>A0A7C3TDE5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKIKVGFAKVGNIGCSPLIEFLLDERAEREDIEVRVFGSGSKMDPESCISIAEETVKYAP
HLIVFTSPNASLPGPSKAREIFQKSNIPTIIVSDNPAKKATKLIEEAGLGYIIVEGDVMI
GARREFLDPVEMACFNSDIIKVLAVTGALEVLRATIDRLITDIKNGGRIELPRIIVNKDR
AVNEAGFNNPYAKAKAASAYEMVRRAGDLTFEGCFVEKDWKRYIELVCAGHEIVRAAAQL
ADEAREIEKGNDMLTRKPHNSEGLTLKKNKLIEKPSSL
>A0A7C5ZSP2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKNVRVGIFKCGNIGTAPLLELLLDELADREDITVRCITTGAKMLVEEVEEALPKIFDFK
PDFIVFISPNPAVRGPTRAREILLERKMPAIFISDAPGKRVIEEFEKAGFGYIVIMGDPL
IGARKEFLDPLEMAIFNANVIKVLAITGVFRIIHQEIDKIIYSIKEELIPQLPRLVIDTE
TIRDRSDFRNPYARAKAMAAYELTKKVAEINTKACFMEKEKEKYIPLVVCAHEIVQIAAK
LAEEAREIEKYSDTLVRKPHSKDGRLKVKEKLMMPLGFDETIHQGEFKP
>A0A524A964|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVNVTFVQAGYIGATTLIDALLDERASRKGISVRVISSGCKMDEAEAEAAAKIAAQVPTD
LYVAVSPGAGLPGPKKMREVLKETGKPIIVVSDEPSRKAAKKLPEEGIGYLVLYGDAMIG
AKRPFLDPIEMALFNADVIRVLSVTGVFRCVYTELDKVIEQIAKGEKPVLPEIVVNKTVA
LEYSGLQNPYARAKAMAAFEAARKVANLDVEGCFKTEGAKNYLPIVAAAHELMRYAAKLC
DEAREMEKANDSVERLVHFRDGTLRKKTQLLGKFE
>A0A7L4PCT3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocellales archaeon|TrEMBL
MAKIGVIKLGNLGISQVVDLLLDERADRDIDVRTAGSGAKMGTSEASYTAKLMEWDPDLV
VVVSPNASLPGPKKSRELVGDKPCIIISDAPAKKAVDELKEKGFGYIILKGDPLIGARRE
FLDPTEMALFNSDALKVLTTCGAARLVQEELDTAIEAIQKGDVKLPQIIVGAETAVNRVR
FSNPYAKAKAIAAYKMAELVAEMNVQTCFVIKEPPRYIMMGAAAHEVMRVAALLADAARE
IEKGLDKVSRRPHADSGQILDKANLLGKPG
>A0A0E3LEA9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina siciliae C2J|TrEMBL
MGPTDAAGTESFKQWNADFVVMISPNAAAPGPTAAREIWKDVPCIVVSDGPTKKEAREAL
EQEGFGYIILPVDPLIGAKREFLDPVEMASFNSDAMKVLSNCGVVRLIQEELDKVTEQVA
SGKSGKDLELPHIFAKPEKCVESAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEVE
QVCLTAAAGHEIMGAAAILATQAREIEKSNDTVLRQPHAKNGTLLKKVKLYEKPE
>A0A7K3Y2G1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMITFMATSGTKLQPEDIDRVVNNMKAWAP
DFCIVVSPNGVLPGPTQARENLAAAGIPCVVITDDITTKKEQFTALKESDFGYIIMKADA
MIGARREFLDPIEMADYNGNLVKVLALTGAFRKMQMELDKVVDQVKAGKKGKDLALPKVV
MTADKAVDGEFSNPYALAKARAAYEIAQQVAAVNVKGCFMTKEWEKYIPIVSSAHEMMRQ
AMILCEEARELEKGMDAVIRKPHKKTGEIVSKTALISKPE
>A0A366M9M5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter sp. NOE|TrEMBL
MVVKIGIIKSGNIGTSPVLDLLLDERADRPNIDVRVIGCGAKMNPNQIEEVTPKVKDFDP
DFAIFISPNPGAPGPAKARELLSGYDIPVVIIGDGPGVGKKDEMKEQGLGYIIVKGDPMI
GARRELLDPTEMASFNADVIKVLALTGAYRVVQNAIDDLIEAADAGKELELPEIILTAEK
AVEAAGFTNPYAKAKAYAAYETAAKVADIDTKGCFMVQDATQYITIVAAAHELIATAAKL
ATEARELEKANDAVLRTPHGGDGSVVSKTKLMDKPS
>H1YWR8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoplanus limicola DSM 2279|TrEMBL
MVVKVGIAKLGNIGSGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVDNMKAWGP
DFCIVVSPNGVLPGPKGAREALAAAGIPCVVITDDITSKKDDFAALKESNFGYIIMKADS
MIGARREFLDPVEMSDYNGNLIKVLTITGAFRKLQLALDAVIDQVKAGKKGAELELPKIV
MTSDKAVADEFTNPYAYAKARAAYEIAQAVAGVNVKGCFMTKGHENYTPIVASAHEMMRS
ATLLCDEAREIEKGCDGVIRMPHKNDGEIVKKTALISKPW
>A0A1V4TTL0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomassiliicoccales archaeon PtaB.Bin134|TrEMBL
MTTKKEWAEIKDGKFGYIIMKGDAMIGARREFLDPIEMADYNGNLVKVLSITGAFRKLQM
ALDQVINQVKAGKKGAELALPKLVVTSDKAVDGEFTNPYALAKARAAYEIAQSVAMVNVK
GCFMTKEWEKYIPIVSSAHEMMRVAAVLCDEARELEKACDGVIRKPHKKDGVIVSKTKLI
SKPE
>A0A7D5E6J4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanolobus zinderi|TrEMBL
MAKIGFIKLGNLGMSQVIDLVQDEIAAREGITVRVFGTGPKMGKDEAAATEELKKFDADF
YVMISPNSSAPGPTAARELYKDVPCIVISDGPTKKDDRAALEEAGFGYIIMTVDPLIGAK
TEFLDPVEMASFNSDAMKVLSTCGVVRLIQEELDKVAAMADEGKELELPHILAKPEKCIE
RAGFNNPYAKAKGLAALHMADMVAKINFPACFMMKEIEQVALTTAAGHEMMRAAAQMAIE
AREIEKANDSVFRQPHSKKGKLLTKTTLYEKPQ
>A0A5E4K9I9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon|TrEMBL
MVVKIGFIKLGNLGTSQVIDLLLDEIAAREGIAVRVFGTGAKMGKDEAEHTKHFKEWSPD
FTVMISPNSSAPGPTAARDVWKGVPTIVVSDGPTKKEDREKLEQAGFGYIILPVDPLIGA
KREFLDPVEMVSFNSDAAKVLSVCGAIRLVQTEIDKVIDQAAAGTKPLALPKILAKPEKC
VESAGFSNPYAKAKALAALHIATKHAEIDFPACIVLKEVDQIPTTAAAGHEALRAAARLA
DEAREMEKANDSVLRKPHAKDGRLLSKTKLLEKPQ
>A0A2P0QM91|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon|TrEMBL
SNLKAYKPDFCIVVSPNGVLPGPTGAREQLAAAGIPVIIITDDVTTKKEWEGVKASKFGY
IIMKADSMIGARREFLDPIEMADYNGNLVKVLAMTGAFRKLQVALDKVIDQVKAGKKGDA
IELPKLIMTTDKAVDGEFTNPFALAKARAAHEIAMAVAGQNVKGCFMTKEWEKYIPIVAS
AHEMMRAAANLCDQARELEKGGDCILRQAHKKDGTLVRKTKLVAKFE
>A0A7K4GWU2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MLKIGILKNGTIGSSLLLAFLMDERAESTRINVREVTSGAKMHPASHCVETMKQLLEFEP
ELIIMSSPNAALPGPKAVREMSGVIPTIVISDAPAKKAIDEIKEKNMGYILVNCDSMIGA
RRPFLDHIEMSIFNSDLLKVLAITGALQVIAEELNKVIMDMLEGRTPSLPQIIIDANIAT
EAAKFSNPYARAKAIAAFELAASVSRVTGKACFQLRERSEYMPLLAAAHEMMRIAALICD
EAREMEKSNDTVIRRPHHAKQQRFLSKIGLYDKEQ
>A0A524D1A8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thorarchaeota archaeon (strain OWC)|TrEMBL
ADEAREIEKSNDTILRTPHRKEMGMRTKTKLLSKSE
>A0A523X559|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Heimdallarchaeota archaeon|TrEMBL
KAGEKPKLPTRNMSAIGVATTYPFSNVYARPKALAALTMLQHAASLNVNGCFVEKDREKA
LIKVAGAHEMVRQAGLLADEVRELEKATDHMIRTPHGKDGKILHKVHFFDEAHEKQ
>F0T7A4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium lacus (strain AL-21)|TrEMBL
MVVKIGIIKCGNIGTSPVIDLLLDERADRPNIDTCVVGSGAKMNPEEIEKAVPLMLEMDR
DFVIFISPNPGAPGPAKARELLSAADVPAIIIGDAPGLRSKDEMDEQGLGYIIVKADPMI
GARREFLDPTEMASFNSDVIKVLALTGAYRVVQNTIDAAVTAVESGETLELPKVVITRDK
AVEAAAFGSPYAKAKAMAAYEIATKVADIDVEGCFMVRDAEKYIPLVASAHEMLGVAAKL
ASEARDIEKANDTVVRTPHGGKGQTLSKVALADKPE
>A0A0F8D2N8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp. 2.H.T.1A.8|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVCGTGAKMGPADAADTESFKQWNADF
VVIISPNAAAPGPTAARELWKDVPCIVVSDGPTKKEAREAFEQDGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLIQEELDRVTEQVASGKSGKELELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
ATQAREIEKSNDTVFRQPHAKSGALLKKVKLYEKPQ
>A0A497J791|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Korarchaeota archaeon|TrEMBL
MVVKVGFVKLGNIGCAPLIDLLLDERAEREDIVVRVIGSGAKMGPEDAEEVSKKILEFNP
DFVVITSPNAALPGPTKAREILAQSVPVIVVSDLPAKKIVPDLEEKGIGYIIVEADAMLG
ARREFLDPIEMALFNADLIKVLSITGVYNILFESIDKVIEAFKEGKKPELPQIIVKGKKA
IKAAGFSNPYAASKALASFEIAKNVADVTVTACFKEKDWEKYTLLCSAAHEMMAQAAKLA
SEAREIEKNADKVLRKPHYDDGTILTKRALIEKPSKPG
>A0A822ISG6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MVVKVGFIKLGNLGTSQVIDLLLDEIAAREGIAVRVFGTGAKMGKEEAAETASFKNWVPN
FVVMISPNSSAPGPTAARDVWKDIPTIVVSDGPTKKEDREKLEQAGFGYMILPVDPLIGA
KREFLDPTEMVIFNTDAAKVLSVCGAIRLVQTEIDKVIDQVAAGTKPLVLPKILAKPEKC
VESAGFNNPYAKAKALAALHIATKVAEIDFPACFVLKEVDQIATAAAAGHEAMRAAARLA
DEAREMEKANDSVLRKPHAKDGRLLTKTKLLEKPQ
>A0A520JXD5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MSDVKIGFVKLGNLGMSQVIDLVLDEIAARKGIMVRTIGTGAKMGADEAKDTEALIKHWD
PDFVVMISPNAGAPGPTAAREIYKDTPTIIVSDGPDKKDGRQALKDAGFGSIILKVDPLI
GAKREFLDPTEMASFNADAMKVLSACGPVRMIQEAFDNVIDQVASGKSGKDLELPYILGS
PEKCVERGCFENPYAKAKALAALHMANTVAAINFPACFIHKDIEKVALTAAAGHEMMTAA
AVLAREAREIEKANDTLFRQPHAGAGNLLTKTKLYDKPT
>A0A284VTV0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Methanoperedens nitroreducens|TrEMBL
MVVKVGFIKLGNLGTSQVIDLLLDEIAAREGIAVRVFGTGAKMGKDEAQETASFKNWGPD
FVVMISPNSSAPGPTAARDVWKGTPAIVVSDGPTKKEDREKLEQAGFGYIILPVDPLIGA
KREFLDPVEMVSFNSDAAKVLSVCGAIRLVQTEIDKVIDQIAAGTKPPALPKILAKPEKC
VESAGFANPYAKAKALAALHIATKVAEIDFPACFVLKEVDQVATTAAAGHEALRAAARLA
DEAREMEKANDSILRKPHAKDGRLLTKTKLLEKPQ
>A0A139D0U3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanohalophilus sp. T328-1|TrEMBL
MGNLGMSQVIDLVQDEIAAREGISTRVFGTGPKMDKETAASTDELKAWEPDFVVMISPNA
SAPGPKSARELWNDYPCIVVSDGPTKKDDRQALEDAGFGYIIMTVDPLIGAKTEFLDAVE
MASFNSDAMKVLSTCGVVRLLQEELDAVTAQVDEGKSGADLELPHILAKPQKCIERAGFN
NPYAKAKGLAALHMASKVAEVNMPACFILKEIEDVALTAAAGHELMRAAAQLAIEAREIE
KANDSVFRQPHSKKGAQLQKIKLYEKPQKV
>A0A099SYF5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcoides methylutens|TrEMBL
MAKIGFIKLGNLGMSQVIDLVQDEIAAREGISVRVFGTGPKMGKAEAAETEAFKEWGADF
YVMISPNSSAPGPTAARELYKDVPCIVISDGPTKKDDRQALEDAGFGYIVMTVDPLIGAK
TEFLDAVEMASFNSDAMKVLSTCGVVRMIQEELDAVAAQVDEGKSGKDLELPHILAKPEK
CIERAGFNNPYAKAKALAALHMADKVAQINFPACFMMKEIEQVTLTTATGHEMMRAAAQL
AIDAREIEKANDSVFRKPHSKKGVQMTKTALYEKPQ
>A0A7J3QFA5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Ignisphaera aggregans|TrEMBL
MAKVCILKLGCIGSAPLLEYLLDERADRGDIEIRVISTGAKMYDEKYGLELAEKGLKEDC
DIYIVVSPNATTPGPTKARETLREKGKHVIVVSDAPTSKIVKDLDAKGFGYIIVLADSMI
GARREFLDPIEMALFNSDLIRVLSVTGVYRLLQLEIDNVINQVKKGVESIQLPKIVVDKE
TVVKYAEFRNPYAKVKAMAAYEMARHVADLTIEGCFRIKEAERYIPIVAAAHEMMRYAAL
LADEAREIEKYGDTVVRTPHSVRGEVLYKEKIMEKPVKKE
>A0A832S7L5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMGPADAADTESFKQWNADF
VVIISPNAAAPGPTAAREIWKDVPCIVVSDGPTKKEAREAFEQEGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLIQEELDKVTDQVASGKSGKDLELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
ATQAREIEKSNDTVFRQPHAKNGALLKKVKLYEKPE
>D2ZP28|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter smithii DSM 2374|TrEMBL
MVVKIGIIKSGNIGTSPVLDLLLDERADRPNIDVRVFGSGAKMNPEQVEDVVPKVDQFDP
DFCIFISPNPGAPGPAKARELLSEKDIPAIIIGDAPGKGKKDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNADILKVLAETGALRLVQNTIDGVIDGAAAGNIELPKLIITAEKA
VEAAGFENPYAKAKAIAAYEMAGAVANLDMKGCFMTKGFENFIPLVAAAHEMAASAAALA
DEAREIEKGNDSVLRTPHMKEGNTGRKTDLISKPE
>D2RET8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus profundus (strain DSM 5631 / JCM 9629 / NBRC 100127 / Av18)|TrEMBL
MRIGIAKLGAIGSAVLLEYCLDELAMRGDIETFVVSSGSKIKVEVLEELEKRDFDLKIVT
CPNAEKFLKDVNLSDRVIVITDRASKDWLDSLNWGYIVVKADAMIGARREFLDPTEMVLY
NSDLLKVLAVTGIIRLLQYEINRALKEDYLPKVVVDYNTAVKFAGFCNPYARAKAIASYI
IAENISKITHKACFVEKDAENYITLCATAHEMMRIAGKLADEAREIEKSNDSVLRTPHSK
SGEILKKVGLYDVLM
>A0A2I0PE10|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon HGW-Methanomicrobiales-3|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLEPADVDRVVSNLKAYQP
DFCIVVSPNGVLPGPTGAREQLAAAGIPTIIITDDVTTKKEWEGVKADTKFGYIIMKADS
MIGARREFLDPVEMSDYNGNLVKVLALTGAFRKMQVALDKVIDQVKAGKKGAELELPKII
MTTDRAVDGEFTNPFALAKARAAHEIAMAVAGQNVKGCFMTKEWEKYIPIVTSAHEMMRV
AAALCDEARELEKAGDCILRQAHKKDGSLVKKTKLVAKFE
>A0A0E3LTE7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina mazei S-6|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMAPADAADTESFKQWNADF
VVIISPNAAAPGPTAAREIWKDVPCIIVSDGPTKKEAREAFEQEGFGYIILPVDPLIGAK
REFLDSVEMASFNADAMKVLSICGVVRLIQEELDKVTEQVASGKSGKDLELPHIFAKPEK
CVEHAGFANPYAKSKALAALHMAEKVAQVNFPACFMLKEIEQVCLTAAAGHEIMGAAAQL
ANQAREIEKSNDTVSRMPHAKNGAVLKKVRLYEKPE
>A0A2D3C6E3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanohalophilus portucalensis|TrEMBL
MVKVGFIKLGNLGMSQVIDLVQDEIAAREGISTRVFGTGPKMDKETAASTEELKAWEPDF
VVMISPNASAPGPKSARELWNDYPCIVVSDGPTKKDDRQALEDAGFGYIIMTVDPLIGAK
TEFLDAVEMASFNSDAMKVLSTCGVVRLLQEELDAVTAQVDEGKSGADLELPHILAKPQK
CIERAGFNNPYAKAKGLASLHMASKVAEVNMPACFILKEIEDVALTAATGHELMRAAAQL
AIEAREIEKANDSVFRQPHSKKGVQLQKTKLYEKPQKV
>A0A328Q0J8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosphaera stadtmanae|TrEMBL
MVVKIGIVKVGNIGTSVLIDMILDERADREDIDVRTISSGAKMGKNQMDDVLPKIDEYNP
DVIIFISPDPGAKSPSSARETLSKKNIPTIVIGDGPGERAIGSMKEQGLGYIIVKADSMI
GARREFLDATEMAVFNSDVLMVLSTTGVFRLIHKTLDKVIRDIDEDKLYSLPELVITAEN
AVDAADFKNPYAKSKAIAAYSIACQVSSMNVRACFKTKDYHVYIPLVSAAHEMMSAASKL
AYEAREIEKSNDTVVRTAHRRNGSILYGTSLNDNKE
>A0A7J3A8C7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Nitrososphaerales archaeon|TrEMBL
MLKIVFAKIGMIGITPMIEGLFDERAVRKDIVIRSVYSGCRMEPSDAKEVLETALALKPQ
LLIFVTPYLQGEGPMAGVEMLIGSGVPSCVVSNTATKEVLNKLEENNIGYIIVDADPMIG
AKKEFLDPVEMCLFNSDIIRV
>A0A843L161|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoculleus sp|TrEMBL
MVVKVGIAKLGNIASGVMGELLLDERADREDMITFMATSGTKLQPEDIDRVVSNMKAWNP
DFCIVVSPNGVLPGPTKAREDLAAAKIPCIVITDDVTTKKEQFDALKASNFGYIIMKADA
MIGARREFLDPIEMADYNGNLVKVLAITGAFRKMQQELDKVIDQVKAGKKGADLALPKVV
MTVDRAVDGEFSNPYALAKARAAYEIAQSVAGVNVRGCFMTKEWEKYIPMVSSAHEMMRQ
AMLLCEEAREIEKSTDGVIRKPHKKTGEIVSKTKLISKPE
>A0A1V4YEE2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium sp. PtaU1.Bin097|TrEMBL
MVVKIGIIKSGNIGTSPVLDLLLDERADRPNIDVRIIGSGAKMNPEQVEEVVPKVKEFEP
DFAIFISPNPGAPGPAKARELLSTYDIPAVIIGDAPGAGKKDEMDEQGLGYIIVKGDPMI
GARRELLDPTEMASFNSDVIKVLALTGAYRIVQNTIDGIIAAVDAGEDIELPKVIITAEK
AAEAAGFTNTYAKAKAIAAYTAAEKVADIDLKGCFMVKDSNQYIPLVAAAHELIAVAAKL
AVEARDIEKGNDTVLRTPHGSDGSTVTKTVLLEKPQ
>F8ALX1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothermococcus okinawensis (strain DSM 14208 / JCM 11175 / IH1)|TrEMBL
MVVKIGIIKCGNIGMSPVIDLALDERADRGNIDVRVLGSGAKMGPEQVEEVTTKMVEEIK
PDFVIYIGPNPTAPGPKKAREILSKSGIPSVIVGDAPGIREKDKMTEEGLGYILIKCDPM
IGARRQFLDPVEMAMFNADVLRVLAGTGALRVVQNAIDDMIEAIEAGNKPELPQIVVTDK
KAVEAANFSNPYAKSKAMAAFAMAEKVADIDVKACFMTKGMENYIPMVAASHELIRYAAK
LVDEARELEKAMDTVSRKPHAADGKRLNKTKLMEKPE
>A0A497MDQ4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVVKVGFAKVGNIATAPLIEFLLDERADRNDIDVRVVSSGAKMGVEQAEEVAKKLLEFKP
DFAVVTSPNATLPGPKRLRELLAEGGIPVIVVSDAPAKKIVKKLQEAGFGYIIVTADAMI
GARREFLDPVEMALFNADLIKVLAVTGVFNIVQVELDKVIDAFKNGEKPTLPRIVIDKDK
AVEAANFSNPYAKAKAMASFEIARRVADLTVEGCFMVKEWERYTLLVAAAHEMMKTAAKL
ADEARELEKATDSVYRSPHSRAGLILSKRKLIEKPAKPV
>A0A7C5VNV4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
EALPKIFEFKPDFIVFISPNPAVRGPTRAREILLERKMPAVFISDAPGKRVIEEFEKAGF
GYIIIMGDPLIGARKEFLDPLEMAIFNANVIKVLAITGVFRIIHQEIDKIIYSIKEELIP
QLPRLVIDTDTIRDRSDFRNPYARAKAMAAYELTKKVAEINTKACFIEKEKEKYIPLVVC
AHEIAQVAAKLAEEAREIEKYSDTLVRKPHSKDGRLKVKEKLMMPLVFDETIY
>A0A550GT57|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MTQEQFKKIGIFKCGNIGTSPLVELLLDELADRQDIKVRTVTTGSKMGPEDVEDVLPKIF
EINPDLLIVISPNTSLPGPRKVREKISSSGLPGIVISDAPGKRAKEEIENQGLGYMIITG
DPLIGARKQFLDPIEMAIFNSNISKVLAITGVYRIVHQEIDNAIYAIENGKKPELPRLVI
DLKTVRDRSEFINPYAKSKAIAAYGLVEKVADINVQACFIEKESEKYIPLVTCAHEIAQA
AARLAEEAREIEKCNDTVVRKPHAKSGELKVKTELMLPPVSNEDFYGKKVS
>A0A832XCJ9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MTEQQSKKIGIFKCGNIGTSPLLELLLDELADRQDIKVRTVTTGSKMGLDDVEEALPKIF
EFNPDLFIVISPNTALPGPAKAREAISSSGRPGVVISDSPAKRAKADIEKQGLGYIIITG
DPMIGARKEFLDAIEMALFNSNINKVLAISGAYRIVHQEIDKLITSLEIGKPPVLPKLVV
DLATIRDNAELSNPYAKAKAMAAYAMAEKLAEINVQACFMEKESEKYIYLVACSHEIAQI
AAKLAEEAREIEKYNDTLLRKPHSKSGKIKTKSKLMQPLAFVEKPQDEGST
>A0A7J3EEZ9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVRVGFAKIGNIGSAPMIEFLLDERADRNDIDVRIVSSGAKMGVEQAEEIANKLLEFKPD
FVVVTSPNASLPGPTRLREMLAEKNIPVIVVSDAPAKKIVKDLQSRGFGYIIVMADSMIG
ARREFLDPVEMALFNSDLIKVLAVTGVFNIIQVELDRVIDAFKQNVKPTLPTVIVAKDNA
VEAAKFSNPYAKAKAMASFEIARVVADLTVEGCFIVKEWERYTTIVAAAHEMMKYAAKLA
DEARELEKSNDNVYRSPHSKVGVILSKRKLIEKPTEQV
>A0A497M777|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKRVKIGVIKCGNIGSAPLFELLLDELADREDIAIRTVTTGPKMIAEAVEDALTRIYDFN
PDLLVFISPNPAVQGPRRARKILSEKAIPCIFISDAPGKRLKEEFEKHGFGYIVVMGDPL
IGARREFLDPTEMAIFNSNIIKVLAITGVYKIILQEVDRVIHELKQNITPKLPRLVIDVD
DIRDKSDFRNPYAKAKAMAAYELTKKVAEINTKACFIEREREKYVPLVACAHEIAQVAAK
LAEEAREIEKYSDTLVRRPHSKDGKPKIKEKLMEKPVFDEETYQSWFE
>A0A497KVH2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MAILGFLKLGYIATSPMVELLLDERAEREDMEVRVVASGANMSPGQAEEVAKAMVEMKPD
IVFVVSPNAATPGPKKAREVIAEAGIPVVVITDGPKKLLEELAEKGMGGIIIEADSMIGA
RREFLDPIEMAIFNADAIKVLAVTGVYNIVYEAIDRIIEQLKRGEKPELPLIRVTRAMAI
EAAGFSNPYAAAKAAAAYEMAKRVSNLTTEACFKEKDWKVYTALCAAAHELMRWAAMLAD
EAREIEKYGDSVLRRPHHRDGSLLSKRRLLEKPSKPSPSPS
>A0A7L4PQM8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon|TrEMBL
MVIKVGVAKLGNIASGVMVELLLDERADRTDMQTFMATSGTKLEVEDVDRVVSNLKAYGP
DFAIVVSPNGVLPGPTGAREALAAAGIPTIVITDDVTTKKEWAELKESKFGYIIQKADAM
IGARREFLDPIEMADYNGNLVKVLSITGAFRKMQLALDEVIDQVKAGKKGAEVVLPKIVV
TADKAVAGEFSNPYAYAKARAAFEIAAAVAMVNVKGCFMTKGFENYVPIVASAHEMMRVA
ALLCDEAREIEKGVDGVVRKPHKNDGTIVSKTALISKPE
>A0A7L4QRR1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobiales archaeon|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVNNMLAWKP
DFAIVVSPNGVLPGPTGARERLAAAGIPVVVITDDVTTKKEWADIKESKFGYIIMKGDAM
IGARREFLDPVEMADYNGNLVKVLALTGAFRKLQMALDQVIDQVKAGKKGADLVLPKIVV
TSDKAVDGEFTNPYALAKARAAYEIASAVAMVNVKGCFMTKEWEKYIPIVTSAHEMMRCA
AVLCDEARELEKAGDGIIRKPHKKDGVIV
>A0A0E3NKS2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp. WWM596|TrEMBL
MGPADAADTESFKQWNADFVVIISPNAAAPGPTAARELWKDVPCIVVSDGPTKKEAREAF
EQDGFGYIILPVDPLIGAKREFLDPVEMASFNSDAMKVLSICGVVRLIQEELDKVAEQVA
SGKSGKDLELPHIFAKPEKCVEHAGFANPYAKAKALASLHMAEKVAQVNFPACFMLKEID
QVCLTAAAGHEIMGAAAILATQAREIEKSNDTVFRQPHAKNGALLKKVQLYEKPQ
>A0A497RCD2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobales archaeon|TrEMBL
MVKVGVLKMGAIGTALLVEYLLDERADREDIDVRVVTSGAKMSPDEAVVAEKLKEFDPDV
VIVVSPNAALPGPKAAREAFEGKPVIIISDAPAKKAKDEFVEKGFGYILINADSMIGARR
EFLDPTEMALFNADVVKVLAATGAFRLVQEAIDKVIEDVKAGKEPELPRVIVTAERAVEA
AKFTNPYAKAKAMAAYYIAEKVADIDVKGCFIEQDPNKYIPLVAAAHEMMRVAAIEADRA
REIEKGGDYVYRNPHAKDGKILSKTKLMEKPE
>A0A0M0BF28|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|miscellaneous Crenarchaeota group archaeon SMTZ1-55|TrEMBL
MSRTVRVGVLKAGCMGSLPLVEFLVDERADRSDVDVLVSGSGAKLGLKQCETITAWIIAQ
KPDFTVLIGPAQQAPGPTKARKLLVEAGVPTVVISDGPARKIVSRLEADGFGYIIIDADA
MIGARREFLDPVEMALFNADMIKILAVTGVLRVITESLDDLIQAVKSGSGLQLPRLLVTK
ESAVASSGLINSYARAKAMAAYEIARHVAGVDSTACFKVPEWTRYVPLVTSGHEMIRAAA
KLADDAREMDKVGDALVRRPHFPDGVLGFKTKLMEKPQRSEKEDSK
>A0A5E4KAB3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon|TrEMBL
MVVKVGFIKLGNLGTSQVIDLVLDEIAAREGIAVRVFGTGAKMGKDEATETASFKLWKPD
FVVMISPNSSAPGPTAGREVWKDTPTIVVSDGPTKKEEREKLEQAGFGYIILPVDPLIGA
KREFLDPVEMVAFNSDAAKILSVCGPIRLVQTEIDKVIDQVAAGTKPLALPKILGKPEKC
VESAGFSNPYAKAKALAALHIATKVAEIDFPACFVLKEVDQVALTAAAGHEAMRAASKLA
DEAREMEKANDSVLRRAHAKDGRLLTKTKLLEKPQ
>A0A2P0QLB0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon|TrEMBL
VKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLEPADVDRVVSNLKAYKPDF
CIVVSPNGVLPGPTGAREQLAAAGIPVVIITDDVTTKKEWEGVKASKFGYIIMKADSMIG
ARREFLDPVEMADYNGNLVKVLALTGAFRKMQLALDKVIDQVKAGKKGDAIELPKVVMTV
DKAVDGEFTNPYALAKARAAYEIASAVAMVNVKGCFMTKEWEKYIPIVASAHEMMKVAAQ
LCDQARELEKAGDSIFRQPHKKDGVLVNKKKLVAKFE
>A0A7K4HBN8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MSEEKFLKIGILKNGTIGSSLLLAFLMDERAEATRIKVREVTSGAKMNPPEECIETMQKL
LEFEPELILMSSPNAALKGPKAARELAGNIPTIVISDAPAKKAIEEFKEKNMGYIIVGCD
SMIGARRPFLDPIEMSYFNSDLLKVLSITGAFNIITNELNKVIMDMLEGKVPTLPQIEIN
ATNATNAANFSNPYAQAKAIAAFELAASVSKITGRACFVLKDRVDYMPLLAASHEMMKTA
AELCIQAREIEKSNDTVLRRPHNTKQYLLTKRKLHEKEE
>A0A524F9Z6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MLNIGILKNGTIGSSLLLAFLMDERAESTRLNVREVTSGAKMHPPEECVETMKKLLEFEP
ELILMSSPNAALKGPMAAREMAREKQIPTIIISDAPAKKAIDEIKEKNMGYILVNCDSMI
GARRPFLDPIEMSCFNSDLLKVLAITGSLQVIAEELNKVIMDMLEGKQPTLPEIIIDAPR
AVQAAKFSNPYAEAKAIAAFELAGSVSKVTSKACFVLKDREEYMPLLAAAHEMMRTAALM
CDQAREIEKSNDTVIRRPHHAKQNLLMKTKLHEKEA
>A0A523RI75|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MLKIGILKNGTIGSSLLLAFLMDERAESKRINVREVTSGAKMNPSEQCVETMQKLLEFEP
DLILMSSPNAALKGPKAARELTGNIPTIVISDAPAKKAIDEFKERNMGYIIVGCDSMIGA
RRPYLDSIEMSCFNADLLKVLAITGVFNIITNELNKVIMDMLQGKPPTLPQITINATNAT
EAAGFSNPYAQAKAFAAFELAVSISKITGKACFTLNDRVEYMPLLAAAHEMMKAAADLCM
EAREIEKSNDSVLRTPHHAKQHILTKRKLHEKEA
>A0A101DXC9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Euryarchaeota archaeon 55_53|TrEMBL
MAKVGFVKLGNLGTSQGIDLLLDEIAQREGIEVRVLGSGAKMTPKEAEESAELKQWGPDF
VIIISPNAMAPGPTKAREIWSDTPTIVISDGPTKKDDRKAIEEAGFGYIIIPMDPLIGAK
RQFLDATEMISFNSDVLKVLSLTGVSRLVKEELDKVIAQVDAGKSGKELELPHILVTPEK
CTERMNFSNPYARAKAMAAAHIASKVPDLTFKACFVYKDIEDIVLAAAAGHEMMRIAAKL
AEESREIEKTLDEVSRMPHAKSGETLSKMKLYEKPQ
>A0A151BKS7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon B63|TrEMBL
MPSVVKIGVLKAGCIGTLPLLEVMLDERADRADIDVRVIGSGAKLGPEQCREVAEQMIRL
KPDLVILIGPAQAAPGPSEARRILSEAGLPTIVISDLPAKKLTGEIEKAGMGYIIVEADS
MIGARREFLDPTEMVLFNSDVIRVLAATGAFNLVVEAIDRAIEALKRGEAPELPRLVIDG
AKAVEAAGFLNPYAGAKALAAYEMARQVSRITTAACFKTQDPKVYIPMVAAAHELMREAA
KLADEAREIEKGQDQVLRRPHFKDGSAGTKRRLMEKPARETLRGAGL
>A0A498GSK7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp. MSH10X1|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRAFGTGAKMSPAEAADTESFKQWNADF
VVIISPNAAAPGPTAAREIWKDVPCIVVSDGPTKKEAREALEQDGFGYIILPVDPLIGAK
REFLDSVEMASFNSDAMKVLSICGVVRLIQEELDRLTDQVASGRSGKELELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
AIQAREIEKSNDTVSRQPHAKNGTLLAKVRLYEKPQ
>A0A3R7IAR3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKKVKIGIFKCGNIGTAPLLELLFDELADREDISVRSVTTGAKMLAEEVEEALPKIFDFN
PDFLVFISPNPAVQGPTRAREILAEKKIPAIFVSDAPGKRLREEFEKHGFGYIIVMGDPL
IGARKEFLDPTEMAIFNSNIIKVLAITGVYRIIYQEIDKIIHCYKEELTPELPKLVIDTA
SIRDNSDFKNPYAKAKAMAAYELTKKIAEINTRACFMEKEKEKYIPLVACAHEIAQVAAS
LAEEAREIEKYADSLVRRPHSRGGRLKVKEKLMLPPVFDEEIYQKWLKGHKRE
>A0A843LP04|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanospirillum sp|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVTNMKAWGP
DFCIVVSPNGVLPGPKGAREALAAAGIPCVVITDDITTKKEEWEALKASEFGYIIMKGDS
MIGARREFLDPIEMADYNGNLIKVLSITGAFRKLQVALDEVIDQVKAGKKGKDLALPKLV
MTSDKAVEGEFSNPYAYAKARAAYEIAQAVAGVNVKGCFMTKGFENYTPIVASAHEMMRQ
ATLLCDEAREMEKATDAVIRKPHKNDGTRVAKKTLISKPE
>A0A8J7XBV4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Theionarchaea archaeon|TrEMBL
MVHLCFVKCGNIATSTVVDLLLDEIAARENIVVTVIGTGAKMTPEETERIAQLLPSIGPD
LVVVCGPNAAAPGMVRLRKNLAKLDVPRIVVGDGPSKRAREKLEEAGFGYLIMEADPLIG
ARREFLDPTEMAIFNADVIKVLAIVGSLRVVQEELDRAIGSVGGTEAYLPRKVVTESASL
AKAGFANPYARAKASSAFMLAVQAAQVNYKGCFVEKDPKKFLRMVTTAHEMVRAAALLAD
EAREIEKSTDSVLRTPHSRSGATLKKRSLKDKPKEVGN
>A0A822J4S3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MVVKVGFIKLGNLGTSQVIDLLLDEIAAREGIAVRVFGTGAKMGKDEAAETASFKNWGPN
FVVMISPNSSAPGPTAARDVWKDTPTIVVSDGPTKKEDREKLEQAGFGYMILPVDPLIGA
KREFLDCVEMATFNTDALKVLAICGAIRLVQTEIDKVIDQVAAGTKPLVLPKVLAKPEKC
VESAGFNNPYAKAKALAALHIATKVAEIDFPACFVLKEVDQVATAAAAGHEAMRAAARLA
DEAREMEKANDSVLRKPHAKDGRLLTKTKLLEKPQ
>A0A849PM70|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MSDVKIGFVKLGNLGMSQVIDLILDEIAARQGIAVRTLGTGAKMGADEAADTEALIKHWD
PDFVVMISPNAGAPGPTAAREIYKNTPTIIVSDGPDKKDARQALKEAGFGSIILKVDPLI
GAKREFLDPTEMASFNADAMKVLSVCGPVRLIQEEIDKVIDQVAAGKSGKDLELPYILGS
PDKCVERGCFENPYAKAKALAALHMANTVAAINFPACFMLKEVEKVSLVAAAGHEMMGAA
AVLAREAREIEKSNDTLFRNPHAKDGKQLAKTKLFDKPA
>A0A7K4HMZ4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanofollis tationis|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVTNMKAWGP
DFCIVVSPNGVLPGPTGAREELAKAGIPVVVITDDITTKKEQFDALKASTFGYIIMKADS
MIGARREFLDPIEMADYNGNLVKVLALTGAFRKLQFELDKVIDQVKAGKKGADLVLPKVV
MTSDKAVEGEFSNPYALAKARAAYEIASAVAGVNVKGCFMTKEWEKYIPIVCSAHEMMRQ
AAVLCDEAREIEKAGDAVIRKPHKKDGVIVSKTALISKPE
>A0A076LFV7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocaldococcus bathoardescens|TrEMBL
MDPESVEDVTKKMVEDIKPDFIIYVGPNPAAPGPKKAREILSQSGIPTIIIGDAPGLRVK
DEMEQQGLGYIIVKCDPMIGARREFLDPVEMALFNADVIRVVAGTGALRIVQEAIDKVID
AIKEGKEPELPRIVINEEKAVEAMEFTNPYAKVKAMAAFVIAEKVGDVDVKGCFMTKEAE
KYIPIVASAHEMLRYAAKLVDEARELEKAMDAVSRKPHSTEGKRLSKKALMEKPQ
>A0A328SR55|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosphaera sp. rholeuAM270|TrEMBL
MVVKIGIIKVGNIGTSTVIDLILDERADREDIDVRTFGTGSKMGKKQVEDVFPEILDYNP
DLIIFISPNPNAKQPSKVRSKLSKLDIPSIVIGDKPGEKVTKQMRDEGLGYILIRADAMI
GARREFLDPTEMALFNADVLKVLSITGTLRLVTNIIDTLLHNMMEKEYVELPEVIVTAEL
AVFNAGFKNPYAMGKAIAAYNMAAMVSEMNIEACFKIDEPDMYIPIVTASHELMSAAAKL
SDEARELEKSNDSVLRTPHAKDGSVWVRQSLVDAYK
>A0A0A7GCQ3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Geoglobus acetivorans|TrEMBL
MVKVGVLKMGAIGTALLVEYLLDERADRGDIEVRVVTSGAKMQPEEAVVAEKLREFDPDV
VIVISPNAALPGPKAAREAFEGKPVIVISDAPAKKAKEEFEEKGFGYILINADSMIGARR
EFLDPTEMALFNSDVVKVLAATGAFRIVQEELDRVIEAIKKGETPELPKMVITAQKAVKA
GNFQNPYAKAKAMAAYFIAEKVADIDVKGCFIERDPEKYIPLVASAHEMMRVAALLADQA
REIEKCNDTVYRTPHSKEGEILKKFELMGKPE
>A0A0E3QZF1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina barkeri MS|TrEMBL
MVNIGFIKMGNLGMSQVINLVQDEIAAREGITVRVFGTGAKMSPAEAAASESFKQWDADF
VIIISPNAAAPGPKAAREVWKDVPCIVVSDGPTKKEAREALEKAGFGYMILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLVQEELDKVTDQVASGKSGKELELPHIFAKPEK
CVEYAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAASQL
AIQAREIEKSNDTVFRQPHAKNGTLLKKVKLYQKPE
>A0A0M0BS79|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|miscellaneous Crenarchaeota group-15 archaeon DG-45|TrEMBL
MVRITFLKIGYIGATNLIDALLDERASRKGISVRVISSGCKMDEEEAVEVAKLAASLPSD
LYVVVSPSAGLPGPTAARGVLRETGKPIIVVSDEPTRKISKDLEEGGFGYIVIYADPMIG
AKQDFLDPVEMVLFNSDVLRVLAVTGVIRLIHSEIDRVIAQLEEGGEVQLPRVVVDKEAA
LEHSGLENPYAHAKAMASFEAARRVANLSTEGTYRVEERERFLPILAAAHELMRQAALMA
DEAREVEKANDSVTRVVHLRSGALRKKTELLGKLEG
>A0A0E3WS34|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina lacustris Z-7289|TrEMBL
MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRAFGTGAKMGPAEAADTESFKQWNADF
VVIISPNSAAPGPTAARELWKDVPCIVVSDGPTKKDAREAFEQDGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSICGVVRLIQEELDRVTEQVASGRSGKELELPHIFAKPEK
CVEHAGFSNPYAKAKALAALHMAEKVAQVNFPACFMLKELDQVCLTAAAGHEIMGAAAIL
ATQAREIEKSNDTVFRQPHAKSGVLLKKVKLYEKPQ
>A0A483CQ80|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanofollis fontis|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVTNMKAWGP
DFCIVVSPNGVLPGPKGAREALAEAGIPCVVITDDITTKKDDFAALKESAFGYIIMKADS
MIGARREFLDPIEMADYNGNLVKVLALTGAFRKLQLELDKVVDQVKEGKKGADLVLPKVV
MTSDKAVDGEFTNPYALAKARAAYEVASAVAGVNVKGCFMTKEWEKYIPIVTSAHEMMRQ
AAVLCDEAREIEKAGDGVIRMPHKKDGVIVSKTALISKPE
>A0A842L9H5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacteriales archaeon|TrEMBL
MVAKIGVLKCGNLGTSPVIDLVLDERADRPNVEIRVMGSGTKMNPDDIEFVVPKMLELDR
DFVIFISPNPGAPGPARARELLSEADVPAMIVGDAPGLRVKDEIEEQGLGYIIVKADSMI
GARREFLDPTEMAAFNADLMKVLALTGAYRVVHNTIDAMIADVEAGKEIELPQLVITRDV
AVEAADFQNPYAKAKA
>A0A2V2ND86|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanospirillum stamsii|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVTNMKAWAP
DFCIVVSPNGVLPGPKGAREALGAAGIPCVVITDDITSKKEEWEALKASEFGYIIMKGDS
MIGARREFLDPIEMADYNGNLVKVLSLTGAFRKLQVALDEVIDQVKAGKKGKDLALPKIV
MTSDKAVEGEFSNPYAYAKARAAYEIAQAVAGVNVKGCFMTKGFENYTPIVASAHEMMRQ
AMVLCDEAREMEKATDAVIRKPHKNDGTRVAKKTLISKPE
>A0A2I0D290|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoregula sp|TrEMBL
FMATSGTKLQPEDIDRVVSNMKAWKPDFCIVVSPNGVLPGPTGAREELAKAGIPCIVITD
DVTTKKEWEGIKTSSFGYIIMKADSMIGARREFLDPVEMADFNGNLVKVLAMTGAFRKLQ
VAVDKVIDQVKAGKKGAELELPKIVMTTDKAVEGEFTNNYALAKARAAHEIAMAVAGQNV
KGCFMTKEWEKYIPIVASAHEMMKVAANLCDEAREIEKAGDTVLRQAHKKDGVLVRKNKL
VAKFD
>A0A120K0H8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobrevibacter sp. YE315|TrEMBL
MVVKIAIIKSGNIGTSPVIDLLLDERADRPNIDVRTFGSGAKMNPEQVEDVVPKIDAFEP
DFAIFISPNPGAPGPARARELLSEKDVPAIIIGDAPGKGKKDEMDEQGLGYIIVMSDPMI
GAKREWLDPTEMAIFNSDILKVLAETGALRLVQKTIDGVIAQADAGEEIELPKLIVTAEK
AAEAGGFANAYAKAKAIAAYEMAGSVANLDMKGCFMTKGFENFIPLVAAAHEIAACAAKL
AQEAREIEKANDTVLRTPHMKEGNPGCKTELISKPQ
>A0A090I8V8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium formicicum|TrEMBL
MVVKIGVIKSGNIGTSPVLDLVLDERADRPNIDVRGVSSGAKMNPEQVEEVVPKIMDFEP
DFVIFISPNPGAPGPAKARELLSGMDVPALIIGDAPGMGKREEMDEQGLGYIVVLGDPMI
GARREFLDPTEMASFNADVIKVLAATGAYRVVQETIDGMIAACEAGEDIELPKVVIDAAK
ATETAGFASPYAKAKAMAAYEMAAKVGDIDLKGCFMVKDMEQYVPIVASAHELIATAAKL
ATEAREIEKANDTVLRKPHGAQGQTMSKTVLVSKPE
>A0A831LUV0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanofollis liminatans|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVTNMKAWGP
DFCVVVSPNGVLPGPTGAREELAKAGIPVVVITDDITTKKEQFDALKASTFGYIIMKADS
MIGARREFLDPIEMADYNGNLVKVLALTGAFRKLQFELDKVINQVKAGKKGADLVLPKVV
MTSDKAVEGEFSNPYALAKARAAYEIASAVAGVNVKGCFMTKEWEKYIPIVCSAHEMMRQ
ASVLCDEAREIEKASDAVIRKPHKKDGVIVSKTALIS
>A0A7J4LQK9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Methanoperedenaceae archaeon|TrEMBL
MVVKVGFIKLGNLSTSQVIDLLLDEIAAREGIDVRTFGTGAKMSKNEADATAEFKNWKPD
FAVMISPNSMAPGPTAARDVWKGVPVVVVSDGPAKKEDRQKLEEAGFGYIILPVDPLIGA
KREFLDSTEMSLFNTDALKVLSAGGAIRLVTEELDKLVDQVAQGKKPELPKILAKPEKCI
EKAGYTNPYAKAKALAALHIATKVAEIDFPACFVLKEVEEIATTAAAGHEAMRAAGKLAD
EAREMEKANDSVLRRPHAKDGRLLSKKKLLEKQQ
>A0A7Z8KMK5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanolobus vulcani|TrEMBL
MAKIGFIKLGNLGMSQVIDLVQDEIAAREGISVRVFGTGPKMGKDEAAATEELKKFDADF
YVMISPNSSAPGPTAAREIYKDVPCVVISDGPTKKDDRAALQEAGFGYIIMTVDPLIGAK
TEFLDPVEMASFNSDAMKVLSTCGVVRLIQEELDKLAAMADEGKELELPHILAKPEKCIE
RAGFNNPYAKAKALAALHMADSVAKINFPACFMMKEIEQVTLTAAAGHEMMRAAAQLAID
AREIEKANDSVFRQPHAKKGYLMTKTALYEKPQQ
>A9A6W8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanococcus maripaludis (strain C6 / ATCC BAA-1332)|TrEMBL
MVVKIGILKCGNIGMSPVIDLCLDERADRNDIDVRVLGSGAKMGPEQVEEVAKKMVEEVK
PDFIVYIGPNPAAPGPKKAREILSAGGIPTVIIGDAPGIKDKDAMAEEGLGYVLIKCDPM
IGARRQFLDPVEMAMFNADVIRVLAGTGALRVVQNAIDEMVFAVEEGKEIPLPKIVITEQ
KAVEAMDFANPYAKAKAMAAFVMAEKTADIDVKGCFMTKEMEKYIPIVASAHETIRYAAK
LVDEARELEKATDAVSRKPHAGDGKILNKCKLMTKPE
>A0A7C3ZJJ5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MPVRVGFLKLGNIGSAPLIELLLDERAERQDIVVRVVSSGAKGVQEVNEAEEVAKKILEF
NPQLIVITSPNAATPGPTRAREVIAPSKIPTIIVSDSPAKKALKSIEDLGMGYIIVEADA
MIGARREFLDPIEMALFNADLVKVLSITGVYNILFETIDKAIVALKEGRSVEPPRIVVDK
EVAVKAAGFSNPYAYAKAMAAYEISRRVADLTVEACFKVKEWERYTVINAAAHEMMLTAA
KLAEEAREIEKYGDTVVRKPHFDDGTILFKRKLVEKPTKQT
>A0A497LXD5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
IAEINTRACFMEKEKEKYIPLVACAHEIAQVAASLAEEAREIEKYADSLVRRPHSRGGRL
KVKEKLMLPPVFDEEIYQKWLKGHKRE
>A0A842XPE8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanophagales archaeon|TrEMBL
MVVKIGFVKLGNIGTSRIVDLLLDERADREDIDARVLGTGAKLTPESAPDTARLLEWNPD
LVVVSSPNAALPGPKQAREMVKAKGKPCIVISDAPAMKAKDKLKEEGFGFIIIPGDPMIG
ARREFLDPVEMSVFNVDVLSVLSITGVARLVQEELDSVIEQIKKGGAVKLPQIIVTAENA
VERARFSNPYAKAKAIAAYNMAEKVADMDVKGCFMMKNPEEYIPMVAAAHELISEAARLA
KEAREIEKQSDSLVRMPHARTGEILKKSKLMEKPSA
>A0A0A8K3Y2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methyloceanibacter caenitepidi|TrEMBL
MAPPRILHMITPLKYMSPFDINMGIDAGYDHAIPYTNATIEDIYGLVQDAIFSRSPEGIK
RQAVFIGGKRAIESLDMMDKAKKAMVPPFEVSVFADPAGSFTTAAAMVACAKTALKKTFD
TDFKDKRVIVYGGTGVVAFASAVIASMDGAKAFLVGYDGPERVRRLTMEANDRFNVDLGY
ADGTTEEQKEELAQSADVIFSAGPAGRQILGLEQFKPAKNLKVVADVNAVPPLGIEGVGI
KDNGVPVEGADGAVGIGALAIGDIKYKTEIGMFKEMIEAKEPVYLDFRAAYRLAQELTS
>A0A7J4ESV5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobaceae archaeon|TrEMBL
MVKLGILKMGALGSAVLLEYLFDERADRENIEVRVVTSGAKMGEGETKVAEELKNFNPDI
CIVVSPNATLPGPSKAREALRANGKPVIVISDSPTKKIKDELKERGFGYILVTADSMIGA
RREFLDSSEMALFNSDVIRVLSATGAFRAIQNEIDRVLNEIKEGEYPLLPQIVLNAEKAV
NAGNFQNPYAKAKAMAAYFIAEKVAEVDVKGCFMEKDPEKYIPLVASAHEMMRKAARLAD
EAREIEKGNDTVFRTPHSKDGKTLSKTGLLEKPA
>A0A6N1YE85|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|methanotrophic endosymbiont of Bathymodiolus puteoserpentis|TrEMBL
MFDPMQNNSPFDINMALDCDFDVLMPYSNVRLESIGRLTQDVIFSRGPSGVKQTAIFIGG
RDLGVAVDMLNGAKKAMVPPFEVSVFADPSGAFTTAAALVACVEKELKEKHNKALKDCKA
LVFGGTGPVGIATGVTTSLAGAQTTLVDHFSKESAQSLAEEYNRRFNSTLSGTVATYDED
KIALIEDADIIFCTAKAGIQILNAEVLSHAKKLKVVGDVNAVPPSGIAGIQLNDFGAPLT
HATASKNAVGIGPLAVGNIKYKVQHALLESMLSGDKPVYLDFIAAFDKARDLLK
>A0A662H0D7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thermoprotei archaeon|TrEMBL
RIVVDKEAAVEAAGFRNPYARAKAMAAYEIARRVADLTVEGCFMVKEWERYTQIVAAAHE
MMRKAAELAKQAREIEKAQDTVLRTPHHRDGTILTKRKLIEKPKRPG
>A0A662TYC4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thermoprotei archaeon|TrEMBL
MSEEGKVVKIGIIKPGAIGTSVILEYLLDERADRKDIDVRIYGTGAKMVVDENLLKAAIE
ANHDLYIVAAPANVKIIKKIAKKLKEAGKRVIIISDEPTKKAAKDFEAEGYGYILVYGDP
MIGARREFLDPTEMALFNSYVLGVLSATGALRIVTEAIDKVIDALKKGEEPELPKLKIDK
NAIEKHGGYTNPYAKAKAIAAYEIARRVASLTTEACFVIQEPERYIVTAAAGHEMLRIAA
KLAEEARELEKAEDVILRTPHHPTGRTLSKKKLLEKPG
>A0A662GDK4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thermoprotei archaeon|TrEMBL
MSTRVKIGVFKLGCIGCAPLLEYLLDERAERKDIMVRVAGSGAKMAEEEALEAAKTLVEF
KPEFAIVVSPNAALPGPTKVREFLKESGIPTIVISDAPAKKIVEDLEGKGFGYIIVTADS
MIGARKEFLDPSEMAIFNADVIKVLAATGVFNIICRELDRVINAFKKGEKPELPKIVVNS
ETAVEAAKFSNPYAKSKAIAAYEMAVSVAK
>A0A5E4IF03|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon|TrEMBL
MFKIGFVKLGNIATSLGIDLALDEIAERNDVEFKILSFGPKMTKTEGDAAAELKAWSPQL
VVITSPNAATAGPTTARENFKGLPTIVISDGPTKKEARDALAAEGFGYIILPVDPLIGAK
REFLDPAEMALFNSDALKVLAACGAVRLVQEELDKAMDAIAKDEAKLPQILATPEKCAER
MDFKNPYARAKAIGALYMAQTVATIDAQACFKLKELGPIALAAAAGHEVMRAAARLADES
RELEKAGDSVSRKPHARSGELMKKTGLLDKPERA
>A0A2P0QL34|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|uncultured archaeon|TrEMBL
TKLEPADVDRVVSNLKAYQPDFCIVVSPNGVLPGPTGAREQLAAAGIPVVIITDDVTTKK
EWEGVKASKFGYIIMKADSMIGARREFLDPVEMSDYNGNLVKVLALTGAFRKI
>A0A2A2H6B2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium bryantii|TrEMBL
MVVKIGIIKCGNIGTSPVLDLLLDERADRPNIDTCVVGSGAKMNPDEIEKAVPLMLEMER
DFVIFISPNPGAPGPAKARELLSAADVPAIIIGDAPGLRAKDEMNEQGLGYIIVKADPMI
GARREFLDPTEMASFNSDVIKVLALTGAYRVVQNTIDEVVATVEAGNEIELPKVVITRDK
AVEAAAFASPYAKAKAMAAYEIATKVADIDVEGCFMTKGAENYIPIVASAHEMLKVAADL
ATQAREIEKANDTVVRTPHGGKGETLAKCCLMEKPE
>A0A524DJI8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Lokiarchaeota archaeon|TrEMBL
MSDLLKIGVLKNGTIGSSLLLSFLIDERAEGEKLEFREVTSGPKMHPAEYCVETMKELLE
YEPDLILMSSPNAALGGPKKARELAGDIPTIVISDAPTKKAKDEIKEKGMGYIIVNCDSM
IGARRPFLDPVEMSFFNSNLLKVLAGTGALKLMMEEINKVIMDLLEGKTPTLPQITIKAD
NATERAEFSNPYARAKAIAAFEIAEKVSQITGKACFVMKERENYMPQLAAAHEMMREAAE
LVQVAREIEKSNNTVVRVPHHKNQYLLKKTKLIEKEEPIK
>A0A3N9UYB3|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothrix sp|TrEMBL
MFKIGFVKLGNIATSTAIDLALDEIAERTDIEFKIVSFGPKMTKKEGEASAELKAWGPQL
VVISSPNAATAGPTTAREIFKGIPTIVISDGPAKKEARDALAAEGFGYIILPVDPLIGAK
REFLDPAEMALFNSDALKVLAACGGIRLVQEELDRAMTALAAGEAKLPTILATPEKCAER
MNFQNPYARAKAIGALYMAQTVATIDAAACFRLKELEQIALAAAAGHEVMRAAGRLADES
RELEKANDSVSRKPHARTGEIMKKTKLLEKPEKI
>A0A524CXH5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thorarchaeota archaeon (strain OWC)|TrEMBL
REFLDATEMVIFNSDIMKILAICGVVRGVHSEIDGIVESIRRGESIIMPRIVMDTNTSLE
YAQLHNSYSNAKAIAALKMAEQAAQLTSAACFRVSDPDEYIALAAAAHEMVRKAAKLADE
IREIEKSIDAVQRTPHSNDGSILSKSSLDEKPK
>F4BZ98|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothrix soehngenii (strain ATCC 5969 / DSM 3671 / JCM 10134 / NBRC 103675 / OCM 69 / GP-6)|TrEMBL
MFKIGFVKLGNIATSTAIDLSLDEIAERTDIEFKIISFGPKMTEKEGKGAEELKAWQPQL
VVISSPNAATAGPTAAREAYRGIPTIIISDGPSKKEAREALSAEGYGYIILPMDPLIGAK
REFLDPAEMALFNSDALRVLAACGAIRLVEEELDRTIASIISGQAKLPTILATPEKCAER
MHFSNPYAQAKAMGALYMAQTVASIDAAACFRLKELKPIALTAAAGHEVMRAAARLADEA
RELEKSNDTVSRQPHARTGELMQKLSLLDKPEKI
>A0A3R7F4K1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanophagales archaeon|TrEMBL
METVKIGFVKLGNIGISRIADLLLDERADREDIDVRVLGTGAKMTPENAADTSRLLDWDP
DVVIITSPNAALPGPKSAREMVKELGKPCIVISDAPAKKAVDKLKEGGFGYIIIPGDPMI
GARREFLDPIEMSLFNADVLSVLSITGVARLVQEEIDAVIGAIKKGEEVKVPQIIATAER
AVERAKFSNPYAKAKAIAAYSMAEKVAELDVKGCFMMKNPEEYVPVVAAAHELLRAAAKL
AFEAREIEKQADSLVREPHSRAGEIMKKEKLMEKPSA
>A0A0F8C1W6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcina sp. 2.H.A.1B.4|TrEMBL
MVNIGFIKLGNLGMSQVINLIQDEIAAREGITVRVCGTGAKMGPADAADTESFKQWNADF
VVIISPNAAAPGPTAARELWKDVPCIVVSDGPTKKEAREAFEQDGFGYIILPVDPLIGAK
REFLDPVEMASFNSDAMKVLSVCGVVRLIQEELDRVTEQVASGKSGKELELPHIFAKPEK
CVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEIDQVCLTAAAGHEIMGAAAQL
ATQAREIEKSNDTVFRQPHAKSGALLKKVKLYEKPQ
>A0A7J4FSM1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MSDVKIGFVKLGNLGMSQVIDLVLDEIAARQGIMVRTLGTGAKMSPDE
>A0A849QX72|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosarcinales archaeon|TrEMBL
MAKVGFIKLGNLGMSQVVDLILDEIAARKGIEIMSFGTGAKMGKVEAEHTKHFKEFEADF
YVMISPNSSAPGPTAAREIWKDKKVIVISDGPTKKDDRQALEDAGFGYIIMKVDPLIGAK
TEFLDPVEMASFNSDAMKVLSTCGVVRLIQEAFDAVIAQADAGKDLELPHVLVSAQKAVE
SAGFNNPYAKAKALAALHMTDKV
>A0A101J2P9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoculleus marisnigri|TrEMBL
MVVKVGIAKLGNIASGVMGELLLDERADREDIITFMATSGTKLQPEDIDRVVSNMKAWGP
DFCIVVSPNGVLPGPVKAREDLAAAGIPCVVITDDVTTKKEQFEALKASNFGYIIMKADA
MIGARREFLDPIEMADYNGNLVKVLALTGAFRKMQMELDRVIDQVKAGKKGADLALPKVV
MTSDKAVEGEFSNPYALAKARAAYEIAQAVAGVNVKGCFMTKEWEKYIPIVASAHEMMRQ
AMFLCEEARNLEKGMDAVIRKPHKKTGEIVSKTTLISKPE
>A0A653R2A7|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Arthrobacter sp. 9AX|TrEMBL
MQIGVFSVSDITTDPTSGRTPTENERIKASVAIAKKVEEIGMDVYAIGEHHNRPFFSSSP
TTTLAYIAAQTERIILSTATTLITTNDPVKIAEDFAMLQHLADGRVDLVLGRGNTAPVYP
WFGKNIQDGVELAIENYSLLRKLWDEDTVNWSGKFRTPLQNFTSTPRPLDGVAPFVWHGS
IRTPQIAEVAAYFGDGFFANNIFWPKEHYQQLIGLYRERYEHYGHGTADQAIVGLGGQFF
MRKNSQDAVKEFRPYFDNAPVYGHGPSLEDFTSQTPLTVGSPQEVIEKTLTFREYFGDYQ
RQLFLIDHAGLPLKTVLEQLDLFGEEVLPVLRKEYAALKPAQVPEPPTHSNRVAAALAAQ
EQDGQDAGAQDTEKSRAEA
>A0A0M0BRF6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|miscellaneous Crenarchaeota group-15 archaeon DG-45|TrEMBL
MVRIGFVKVGNIATSPMVELLLDERAEREDMEVRVLTSGANMGAKQSEDVAKSMIALKPD
VAFVASPNASTKGPTRAREVLAEAGIPVVVITDGPGKLLEELGAKGLGGIIVEADSMIGA
RREFLDPIEMAIFNADTTKVLSVTGVYNVVYAAIDAVIEQLKAGKKPELPLISVTSEMAI
EAAGFSNPYARAKAAAAYEMARRVASLTTRACFREKDWEVYTALCAAAHELMRSAAVLAD
EAREIEKYGDSVLRRPHFDDGSTLEKRRLIEKPR
>A0A7C5XLQ0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Ignisphaera aggregans|TrEMBL
MVKVCILKLGCIGSAPLLEYLLDERADRGDIEIRVISTGAKMYDEKYGLELAEKGLKEDC
DIYIVVSPNATTPGPTKAREALREKGKHVIVISDAPTSKIVKDLDAKGFGYIIVLADSMI
GARREFLDPIEMALFNSDLIRVLSVTGVYRLLQLEIDNVINQIKKGVESIQLPKIVVDKE
TIVKYAEFRNPYAKVKAMAAYEIARHVADLTVEGCFRIKEAERYIPIVAAAHEMMRYAAL
LADEAREIEKYGDTVVRTPHSVRGEVLYKEKIMEKPVKKE
>L0HKS1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanoregula formicica (strain DSM 22288 / NBRC 105244 / SMSP)|TrEMBL
MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVSNMKAWKP
DFCIVVSPNGVLPGPTGAREELAKSGIPCIVITDDVTTKKEWEGIKTSSFGYIIMKADSM
IGARREFLDPIEMADFNGNLVKVLAGTGAFRKLQVAIDQVIDQVKAGKKGAELVLPKIVM
TTDKAVDGEFTNNYALAKARAAHEIAMAVAGQNVKGCFMTKEWEKYIPIVASAHEMMKVA
AALCDEAREIEKAGDTVLRQAHKKDGVLVRKNKLVAKFD
>A0A151BHW8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon B26-2|TrEMBL
MPETVKVGIVKVGCIGVLPLIEVLLDERADRSDIDVRVVGSGAKLGLEQCREVTDLMVRQ
KPDLVILIGPAQAAPGPTEARRLLAEAGIPTIMISDSPAKKLAKNMEKEGLGYIIVEADS
MIGARREFLDPTEMALYNSDVIRVLAATGALSLIVREIDKVIDSLKRGEEPVLPRLTIDK
GLIASNFKNPYAGAKAVAAYEIARNVAKLNTEACFKVQEWTVYTQLAASGHEMMRTAAEL
ADEARELEKSNDSVLREPHFKDGTLGEKRALIEKPKKRL
>A0B7C4|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)|TrEMBL
MFKIGFIKLGNIASSLVVDLALDEIAERTEIESKVVSHGPKMSRGEGERLAEEMRAWGPQ
MVVVVSPNAATPGPTAARSMLKGIPLIVISDGPTKKEARDAMETEGFGYIILPMDPLIGA
KREFLDPAEMAIFNADALKVLSICGAVRLVQEEIDRAIASVAAGSPQLPHILATPELCAE
RMDFANPYARAKAIAALYMAQTAASIDAQACFRLKELEAIALAAAAGHEVIRAAARLADE
ARELEKSGDTVSRKPHARSGDLLVKRKLLEKPARI
>A0A7J3A7L5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Nitrososphaerales archaeon|TrEMBL
MVLKVGFAKVGCIGSAVLIEYLLDERAEREDIDVRVVSSGAKLGVEQATEVGQKLVEMKP
NLVIITSPNAALPVPTKLREIFKEAGLPTIIVSDAPAKKAVKAIEEAGQGYIIVEADSML
GARREFLDPVEMALFNAHIVKVLAITGAFNILRNEIDAVIDALKRGEKPTLPRVVIDKEK
AVANSGLQNPYARAKAMAAYEMARRVADLTVEGCFVVKEMERYMPLIAAGHEMLAAAAML
ADEARSIEKCNDTVYRSPHYDDGTILRKFKFAEKPSKPSA
>A0A7C3TFZ1|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Nitrososphaerales archaeon|TrEMBL
KLVEMKPNLVVIASPNAALPGPTKLREIFKEANLPTITVSDAPAKKAVKSIEEAGQGYII
VEADSMLGARREFLDPVEMALFNANIVKVLAITGAYNILRNELDAVIDALKRGEKPSLPR
IIIDKEKAVANSGLQNPYARAKAMAAYEMARRVADLTVEGCFVVKEMERYMPIIAAGHEM
LAAAALLADEVRSIEKCNDTVYRSPHYDDGTILTKYKFAEKPSKPST
>A0A1D2W4S5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanobacterium sp. A39|TrEMBL
MVVKIGIIKCGNIGTSPVLDLLLDERADRPNIDTCVVGSGAKMNPDEIEKAVPLMLEMER
DFVIFISPNPGAPGPAKARELLSAADVPAIIIGDAPGLRAKDEMNEQGLGYIIVKADPMI
GARREFLDPTEMASFNSDVIKVLALTGAYRVVQNTIDEVVATVEAGNEIELPKVVITRDK
AVEAAAFASPYAKAKAMAAYEIATKVADIDVEGCFMTKGAENYIPIVASAHEMLKVAADL
ATQAREIEKANDTVVRTPHGGKGETLAKCCLMEKPE
>F2KNE0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobus veneficus (strain DSM 11195 / SNP6)|TrEMBL
MRIGIIKLGAIATALLIDYMLDERADREDIDVRTITSGSKLRERDAEIVDKMREFNPDLV
IVASPNAALPAAKLARDALKAEGKPVIVISDAPAKKVKDELEAEGFGYILVNADSMIGAR
REFLDPTEMCLYNSDVIKVLAATGAFRAVQLAVDEAIESAKAGKPKLPRLIIDAEAAVNA
GNFSNPYARAKAMAAYTIAEKVAAVTTKACFVEKDAEKYIPMVAAAHEMMRYAAKLAEEA
REIEKSSDAVYRTPHAKDGRVLSKWGLMEKPS
>A0A497RR88|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Altiarchaeales archaeon|TrEMBL
MSAERPVRIGVVKTGNIGSSVLLDILLDERAERGDIIV
>A0A328RUL0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanosphaera sp. SHI1033|TrEMBL
MVVKIGIIKVGNIGTSPIIDLVLDERADRDDIDVRTISSGAKMGKKQMEDVLPKITEFNP
DMIIFISPNPNAKQPSIAREALSKTGIPTIIIGDRPGEKAIDEMKEQKLGYILVRADPMI
GARREFLDPTEMALFNSDVLKVLSVTGAFRLVHETIDGLIDKISNNEPIEVPQIVVTAER
AVLAAGFKNPYAMSKAIAAYNIATQVSVMDVKACFKTNEPNIYIPLVAAAHEMMSSAAKL
ADEAREIEKGNDTVLRTPHRRDGSTLHKTSLMDNFE
>A0A7C0V4P0|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVRVTFLKIGFLGVSNLIEALLDERASRRGLSVRVVSTGCKMDEEEAVEAAKLAATIPSD
LYVVVSPNAALPGPKEARELLRETGKPVIVVSDEPTKKIADELAEGGFGYILIYADSMIG
ARREFLDPIEMALFNSDVLRVLAVTGVLRLVHMELDRVIRQIEAGEQPELPRVRVTKERA
LKMSGLNNPYAYAKAMASFEMARRVAALSTEGCFKVKERERYIPIVAAAHELMHWAAMLA
DEAREIEKANDAVTRIVHFRDGSLRRKRKLYEKYEALTDL
>A0A7J3J6B5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKKIKVGIFKCGNIGTAPLLELLLDELADREDISVRVITTGAKMLAEEVEEALPKMFDFN
PDFIVFISPNPAVQGPKRAREILLEKKVPSIFISDAPGKRLKEEFEAQGFGYIIIMGDPL
IGARKEFLDPTEMAVFNSNIIKVLAITGVYKIIQQEIDRIIQCCKEGLTFQLPRLIIDTD
TVRDYSDFRNPYALAKAMAAYELTKKVAEINARACFMEKEKEKYIMLVACAH
>A0A7C4WJW9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVKVGFAKIGNIGSAPMIEFLLDERADRNDIDVRIVSSGAKMGIEQAEEVANKLLEFKPD
FVVVTSPNASLPGPTRLREILAEKNIPVIVVSDAPAKKIAKDLQSKGFGYIIVMADSMIG
ARREFLDPVEMSLFNSDLIKVLAVTGVFNIIQVELDRVIEAFKQNVKPTLPTIIITKDNA
VEAAKFSNSYAKAKAMASFEIARVVADLTVEGCFIVKEWERYTAIVAAAHEMMRYAAKLA
DEARELEKSNDSVYRTPHSKVGVILSKRKLIEKPAEQV
>A0A7J3BDA9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVVKIGFVKLGCIGSSVLLDLLLDERAERQDIEVRVASAGAKMAAGSAEEVALKAKEFES
DFYVVTSPNASLPGPTKAREVLAATGKHVIVVSDGPAEKISADLAKKGFGYIIVHADSMI
GARREFLDPVEMAIFNSDMIKVLSITGVYNILYREIDRIIESLKANLPVSPCAVIVDKEN
AVSAAGFQNPYARAKAMAAFEIARNVSKVTTEGCFKVQERDRYVTIVASAHEMLRTASKL
AEEAREIEKSNDAVLRRPHYDDGAQLEKRRLMEKPVKPSTQSQQPFT
>A0A7C4HDX6|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MEVVKVCVVKAGNIGSAPLLELLLDERADRSDIDVRVISSGAKLNPEQAEEIAEKVFDFK
PDLVLVVSPNAALPGPSKIREVMAKAGVPTISITDAPGKRAREDIEGKNQGYIIVNADAM
IGARREFLDPVEMAIFNADVIRVLAITGAFSVIYREIDKVIDAIKKGATPELPRIVVDKD
VAVGAAGFSNPYAKAKAIAAYEAASKVADLNVEGCFKIQDPEKYIPIIAAAHELMRQAAR
LADEARELEKSGDTILRMPHRKSGEIASKRKLLEKPA
>A0A7J4P265|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MVRVTFVKIGYIATTTLIDALLDERSGRKDLQMRSVSSSVSMEEDASLDVARMAAGIPSD
LYVVVSPNAAMPGPTKAREALRATGKPIIVVSDEPSRKALKENPVEGVGYIVVTNDPMIG
AKQSFLDPVEMALFNADAIRVLAVTGSFRIVQQELDKVIEQIGRGEKPTLPQVVIEKEAA
LAAAHISNPYAQGKAMAAFEASRRVANLSTEGTFKVEEPERYLPILAAAHELLRQAAKTA
DEAREIEKGNDTAARLTHFSKGETRKKVKLGDKFEK
>A0A3R7I628|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Candidatus Bathyarchaeota archaeon|TrEMBL
MKKVKIGIFKCGNIGTAPLLELLFDELADREDISVRSVTTGAKMLAEEVEEALPKIFDFN
PDFLVFISPNPAVQGPTRAREILAEKKIPAIFVSDAPGKRLREEFEKHGFGYIIVMGDPL
IGARKEFLDPTEMAIFNSNIIKVLAITGVYRIIYQEIDKIIHGYKEELTPELPKLVIDTA
SIRDNSDFKNPYAKAKAMAAYELTKKIAEINTRACFMEKEKEKYIPLVACAHEIAQVAAS
LAEEAREIEKYADSLVRRPHSRGGRLKVKEKLMLPPVFDEEIYQKWLKGHKRE
>A0A662VIF8|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobales archaeon|TrEMBL
IEQIKRGEKLKLPRLIVTAQKAVEAGRFSNPYAKAKAMASYFIAEKVADVTVKACFVEKD
PNNYIPLVCSAHEMMRIASKLAEEAREIEKSNDTVFRNPHARDGRVLSKVRLMEKPK
>A0A497RM31|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Archaeoglobales archaeon|TrEMBL
MRVGIAKLGAMGSSILLEYCLNEVAMREDFETFVVSSGSRIDLRIIDEIERGEFDLKIVA
CPDAERNLKRKITGRVVVVTDRASEDWLESVDWGYIVVKADSMIGARMEFLDPTEMVLYN
SDILKVLAVTGVYRLLQFEIERALRGDYLPRVVVDFDKALEYAGFSNPYAKAKAIASYII
AEEVSKITRRACFHERDLERFTTLCAAAHEMMRVAGILADSAREVEKSNDTVLRTPHSRY
GDILSKTRLYDLPR
>A0A662J1F9|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thermoprotei archaeon|TrEMBL
MSGKETVVKVGIVKLGCVGTAPMLEFLLDERADRKDIDVRVVSSGAKMDPDKAEEVAKKL
LDFKPHFAIVVSPNAALPGPTKAREILKEAGLPVIVISDAPAKKAMGDLESKGFGAIIVE
ADAMIGARREFLDPVEMACFNADIIKVLAATGVYNIVVDYVDRVIAAFKEGKTPELPRVV
VDKETANAATGYSNPYAKAKAMAAFETARRVADLTTEACFKIQEWERYTPIAAAAHEMLR
NAAKLADEAREIEKYSDTLQRAPHAKDGSPMVKSKLMEKPVKK
>A0A2V2MXR2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanospirillum lacunae|TrEMBL
MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVSNMKAWGP
DFCVVVSPNGVLPGPKGAREALAAAGIPCVVITDDITSKKEEWEALKASEFGYIIMKGDS
MIGARREFLDPIEMADFNGNLVKVLALTGAFRKLQVALDEVIDQVKAGKKGKDLALPKIV
MTSDKAVEGEFSNPYAYAKARAAYEISSAVAGVNVKGCFMTKGFENYTPIVASAHEMMRQ
AAFLCDEAREMEKATDAVIRKPHKNDGTRVAKKTLISKPE
>A0A7C1BTG5|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanomicrobia archaeon|TrEMBL
MVKVGFVKLGNIGASRIVDLLLDERADREDVDVRVLGTGAKMTPDCAADASRLLDWDPDL
VVVVSPNAALPGPKRAREMAKEKGKPCIVISDAPAKKAVPKLKEGGFGYIIIPGDPMIGA
RREFLDPVEMSLFNADVLSVLSITGVAKLLQEEIDAVVEAVKSGASGPSGASGEEVKLPQ
IIATAEKSVERAGFSNPYAKAKALAAYSMTEKVAELDVKGCFMMQKPEEYVPVVAAAHEL
LREAAKLAFEAREMEKQTDSLVREPHARSGEIMRKVGLLEKPSA
>C7P934|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanocaldococcus fervens (strain DSM 4213 / JCM 15782 / AG86)|TrEMBL
MVVKIGIIKCGNIGMSPVVDLALDERADRKDIAVRVLGSGAKMDPESVEEVTKKMVEEVK
PDFIIYIGPNPAAPGPKKAREILSQSGIPSIIIGDAPGLRVKDEMEQQGLGYIIIKCDPM
IGARREFLDPVEMALFNSDVLRVLAGTGTLRVVQEAIDKMIDAIKEGKEPELPRIVINEQ
KAVEAMEFTNPYAKAKAMAAFVIAEKVADVDVKGCFMTKEAEKYIPIVASAHEMIRYAAK
LVDEARELEKAMDAVSRKPHHPEGKRLSKKALMEKPQ
>A0A497PH79|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thorarchaeota archaeon (strain OWC)|TrEMBL
MKIAVVKLGCIGTLPLLDIMIDERADRKDVEIRAFSSGSKMDTTSCEDVTRTVLAYGPDL
VLLVSPNATLSGPTKARNALLSASIPTIAITDGPGQKAFMVKDEQGKKRPVQVEGLGFVV
IPQDPMIGARREFLDPTEMVLFNGELLKVLSVTGVIRKLQKVIDRVIEDIRNKCAPSLPR
LVLHSEEAAAEAGFANPYAASKAIAALKILEALAKVSSEACFKAKDRNKYVLLASAAHEM
LRAAALLADEIRELEKSNDAILRTSHRADGSVKRYLSLLEDD
>A0A524G9H2|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Thorarchaeota archaeon (strain OWC)|TrEMBL
MSFKLAVVKIGCIASSPLLDLIFDERAECKDLEIRTFGSGAKMDVDTCRTLMEYVIEYTP
NLTLLVSPNASLKGPSTARGILQETDNYFLSISDAPARKAWYMKDENGKELIQVSKREGF
IIVYSDPMIGARAEFLDPTEMVLFNSDALKVLAIGGVIRAIQNEVGKVISDIKKGNQPNL
PKVILDAEDAVEYANFQNPYAKAKALASLKITESVAGVTSKACFRSKNAEDYIPLAASGH
EMMRVAANLADEAREIEKAQDSVHRSPHGSDGRIKSKMRLMDKPK
>P94951|methylenetetrahydromethanopterin dehydrogenase|EC 1.5.98.1|Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)|Swiss-Prot
MTVAKAIFIKCGNLGTSMMMDMLLDERADREDVEFRVVGTSVKMDPECVEAAVEMALDIA
EDFEPDFIVYGGPNPAAPGPSKAREMLADSEYPAVIIGDAPGLKVKDEMEEQGLGYILVK
PDAMLGARREFLDPVEMAIYNADLMKVLAATGVFRVVQEAFDELIEKAKEDEISENDLPK
LVIDRNTLLEREEFENPYAMVKAMAALEIAENVADVSVEGCFVEQDKERYVPIVASAHEM
MRKAAELADEARELEKSNDAVLRTPHAPDGKVLSKRKFMEDPE