Sequence of HMDH_SCHPO
EC Number:1.1.1.34
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
hydroxymethylglutaryl-CoA reductase (NADPH)
Q10283
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
1053
114877
Reaction
(R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+
Other sequences found for EC No. 1.1.1.34
General information:
Sequence
0 MIYKLAARYP IQVIAIVGIL VSMAYFSFLE ALTQEDFPVL IRALKRFGIL DGFPNTRLPN
60 EMILKLSSVQ GEDASVWEQI PAAELGGEGF VDFDITQWYY PANAKVDVAQ LVEPYRNDCI
120 FHDASGACHF FFKEVGNWTV SSIALPSNLA NPPIDYFLDS SSTVIQRILP AIREHGISWS
180 WLLQLIARTW MNTLKIASQA SKTELLIVGT AYACMLISIV SLYLKMRRLG SKFWLFFSVL
240 LSTLFSVQFA MTLVRASGVR ISLVSLIESL PFLINVVALD KAAELTRQVI TRCSVSDSHS
300 PMHEDIAKAC RNAAPPILRH FSFGIVVLAI FSYCNFGIKQ FFLFAAVMIY DLLLLFSFFV
360 AILTLKLEMR RYNAKDDVRK VLIEEGLSES TARHVADGND SSATTSAGSR YFKVRYGTKI
420 ILFIFIAFNL FELCSIPFKH YAATSAAAAR LIPLVRSQYP DFKSQRLLDD GVFDDVLSAI
480 SSMSNIESPS VRLLPAVFYG AELSSTSFLS TIHSFINNWS HYISASFLSK WIVCALSLSI
540 AVNVFLLNAA RLNSIKEEPE KKVVEKVVEV VKYIPSSNSS SIDDIQKDEI AQESVVRSLE
600 ECITLYNNGQ ISTLNDEEVV QLTLAKKIPL YALERVLKDV TRAVVIRRTV VSRSSRTKTL
660 ESSNCPVYHY DYSRVLNACC ENVIGYMPLP LGVAGPLIID GKPFYIPMAT TEGALVASTM
720 RGCKAINAGG GAVTVLTRDQ MSRGPCVAFP NLTRAGRAKI WLDSPEGQEV MKKAFNSTSR
780 FARLQHIKTA LAGTRLFIRF CTSTGDAMGM NMISKGVEHA LVVMSNDAGF DDMQVISVSG
840 NYCTDKKPAA INWIDGRGKS VIAEAIIPGD AVKSVLKTTV EDLVKLNVDK NLIGSAMAGS
900 VGGFNAHAAN IVTAVYLATG QDPAQNVESS NCITLMDNVD GNLQLSVSMP SIEVGTIGGG
960 TVLEPQGAML DLLGVRGAHM TSPGDNSRQL ARVVAAAVMA GELSLCSALA SGHLVKSHIG
1020 LNRSALNTPA MDSSAKKPAT DALKSVNSRV PGR
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
43832
Lum P.Y.,Edwards S.,Wright R.
Molecular, functional and evolutionary characterization of the gene encoding HMG-CoA reductase in the fission yeast, Schizosaccharomyces pombe.
Yeast
12
1107-1124
1996
43833
Wood V.,Gwilliam R.,Rajandream M.A.,Lyne M.H.,Lyne R.,Stewart A.,Sgouros J.G.,Peat N.,Hayles J.,Baker S.G.,Basham D.,Bowman S.,Brooks K.,Brown D.,Brown S.,Chillingworth T.,Churcher C.M.,Collins M.,Connor R.,Cronin A.,Davis P.,Feltwell T.,Fraser A.,Gentles S.,Goble A.,Hamlin N.,Harris D.E.,Hidalgo J.,Hodgson G.,Holroyd S.,Hornsby T.,Howarth S.,Huckle E.J.,Hunt S.,Jagels K.,James K.D.,Jones L.,Jones M.,Leather S.,McDonald S.,McLean J.,Mooney P.,Moule S.,Mungall K.L.,Murphy L.D.,Niblett D.,Odell C.,Oliver K.,O'Neil S.,Pearson D.,Quail M.A.,Rabbinowitsch E.,Rutherford K.M.,Rutter S.,Saunders D.,Seeger K.,Sharp S.,Skelton J.,Simmonds M.N.,Squares R.,Squares S.,Stevens K.,Taylor K.,Taylor R.G.,Tivey A.,Walsh S.V.,Warren T.,Whitehead S.,Woodward J.R.,Volckaert G.,Aert R.,Robben J.,Grymonprez B.,Weltjens I.,Vanstreels E.,Rieger M.,Schaefer M.,Mueller-Auer S.,Gabel C.,Fuchs M.,Duesterhoeft A.,Fritzc C.,Holzer E.,Moestl D.,Hilbert H.,Borzym K.,Langer I.,Beck A.,Lehrach H.,Reinhardt R.,Pohl T.M.,Eger P.,Zimmermann W.,Wedler H.,Wambutt R.,Purnelle B.,Goffeau A.,Cadieu E.,Dreano S.,Gloux S.,Lelaure V.,Mottier S.,Galibert F.,Aves S.J.,Xiang Z.,Hunt C.,Moore K.,Hurst S.M.,Lucas M.,Rochet M.,Gaillardin C.,Tallada V.A.,Garzon A.,Thode G.,Daga R.R.,Cruzado L.,Jimenez J.,Sanchez M.,del Rey F.,Benito J.,Dominguez A.,Revuelta J.L.,Moreno S.,Armstrong J.,Forsburg S.L.,Cerutti L.,Lowe T.,McCombie W.R.,Paulsen I.,Potashkin J.,Shpakovski G.V.,Ussery D.,Barrell B.G.,Nurse P.
The genome sequence of Schizosaccharomyces pombe.
Nature
415
871-880
2002
43834
Wilson-Grady J.T.,Villen J.,Gygi S.P.
Phosphoproteome analysis of fission yeast.
J. Proteome Res.
7
1088-1097
2008
43835
Fang Y.,Imagawa K.,Zhou X.,Kita A.,Sugiura R.,Jaiseng W.,Kuno T.
Pleiotropic phenotypes caused by an opal nonsense mutation in an essential gene encoding HMG-CoA reductase in fission yeast.
Genes Cells
14
759-771
2009
