Sequence of SPEB_STRP3

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
streptopain
P0DD38
Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)
398
43174
Reaction
preferential cleavage with hydrophobic residues at P2, P1 and P1'
Sequences with same EC No.
Sequence
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  0 MNKKKLGIRL LSLLALGGFV LANPVFADQN FARNEKEAKD SAITFIQKSA AIKAGARSAE
 60 DIKLDKVNLG GELSGSNMYV YNISTGGFVI VSGDKRSPEI LGYSTSGSFD ANGKENIASF
120 MESYVEQIKE NKKLDTTYAG TAEIKQPVVK SLLDSKGIHY NQGNPYNLLT PVIEKVKPGE
180 QSFVGQHAAT GCVATATAQI MKYHNYPNKG LKDYTYTLSS NNPYFNHPKN LFAAISTRQY
240 NWNNILPTYS GRESNVQKMA ISELMADVGI SVDMDYGPSS GSAGSSRVQR ALKENFGYNQ
300 SVHQINRSDF SKQDWEAQID KELSQNQPVY YQGVGKVGGH AFVIDGADGR NFYHVNWGWG
360 GVSDGFFRLD ALNPSALGTG GGAGGFNGYQ SAVVGIKP
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
476400
Kapur V.,Topouzis S.,Majesky M.W.,Li L.L.,Hamrick M.R.,Hamill R.J.,Patti J.M.,Musser J.M.
A conserved Streptococcus pyogenes extracellular cysteine protease cleaves human fibronectin and degrades vitronectin.
Microb. Pathog.
15
327-346
1993
476401
Beres S.B.,Sylva G.L.,Barbian K.D.,Lei B.,Hoff J.S.,Mammarella N.D.,Liu M.-Y.,Smoot J.C.,Porcella S.F.,Parkins L.D.,Campbell D.S.,Smith T.M.,McCormick J.K.,Leung D.Y.M.,Schlievert P.M.,Musser J.M.
Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence.
Proc. Natl. Acad. Sci. U.S.A.
99
10078-10083
2002