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Sequence of GEPH_RAT

EC Number:2.7.7.75

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
molybdopterin adenylyltransferase
Q03555
Rattus norvegicus
768
83266
Reaction
ATP + H2Dtpp-mP = diphosphate + H2Dtpp-mADP
Other sequences found for EC No. 2.7.7.75

General information:

Sequence
show sequence in fasta format
  0 MATEGMILTN HDHQIRVGVL TVSDSCFRNL AEDRSGINLK DLVQDPSLLG GTISAYKIVP
 60 DEIEEIKETL IDWCDEKELN LILTTGGTGF APRDVTPEKF PTFPFCGLQK GATKEVIERE
120 APGMALAMLM GSLNVTPLGM LSRPVCGIRG KTLIINLPGS KKGSQECFQF ILPALPHAID
180 LLRDAIVKVK EVHDELEDLP SPPPPLSPPP TTSPHKQTED KGVQCEEEEE EKKDSGVAST
240 EDSSSSHITA AALAAKIPDS IISRGVQVLP RDTASLSTTP SESPRAQATS RLSTASCPTP
300 KQIRRPDESK GVASRVGSLK VQSRCSSKEN ILRASHSAVD ITKVARRHRM SPFPLTSMDK
360 AFITVLEMTP VLGTEIINYR DGMGRVLAQD VYAKDNLPPF PASVKDGYAV RAADGPGDRF
420 IIGESQAGEQ PTQTVMPGQV MRVTTGAPIP CGADAVVQVE DTELIRESDD GTEELEVRIL
480 VQARPGQDIR PIGHDIKRGE CVLAKGTHMG PSEIGLLATV GVTEVEVNKF PVVAVMSTGN
540 ELLNPEDDLL PGKIRDSNRS TLLATIQEHG YPTINLGIVG DNPDDLLNAL NEGISRADVI
600 ITSGGVSMGE KDYLKQVLDI DLHAQIHFGR VFMKPGLPTT FATLDIDGVR KIIFALPGNP
660 VSAVVTCNLF VVPALRKMQG ILDPRPTIIK ARLSCDVKLD PRPEYHRCIL TWHHQEPLPW
720 AQSTGNQMSS RLMSMRSANG LLMLPPKTEQ YVELHKGEVV DVMVIGRL
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
421815
Prior P.,Schmitt B.,Grenningloh G.,Pribilla I.,Multhaup G.,Beyreuther K.,Maulet Y.,Werner P.,Langosch D.,Kirsch J.,Betz H.
Primary structure and alternative splice variants of gephyrin, a putative glycine receptor-tubulin linker protein.
Neuron
8
1161-1170
1992
421817
Meier J.,De Chaldee M.,Triller A.,Vannier C.
Functional heterogeneity of gephyrins.
Mol. Cell. Neurosci.
16
566-577
2000
421818
Sola M.,Bavro V.N.,Timmins J.,Franz T.,Ricard-Blum S.,Schoehn G.,Ruigrok R.W.H.,Paarmann I.,Saiyed T.,O'Sullivan G.A.,Schmitt B.,Betz H.,Weissenhorn W.
Structural basis of dynamic glycine receptor clustering by gephyrin.
EMBO J.
23
2510-2519
2004
421819
Kirsch J.,Wolters I.,Triller A.,Betz H.
Gephyrin antisense oligonucleotides prevent glycine receptor clustering in spinal neurons.
Nature
366
745-748
1993
421820
Kneussel M.,Haverkamp S.,Fuhrmann J.C.,Wang H.,Waessle H.,Olsen R.W.,Betz H.
The gamma-aminobutyric acid type A receptor (GABAAR)-associated protein GABARAP interacts with gephyrin but is not involved in receptor anchoring at the synapse.
Proc. Natl. Acad. Sci. U.S.A.
97
8594-8599
2000
421821
Stallmeyer B.,Schwarz G.,Schulze J.,Nerlich A.,Reiss J.,Kirsch J.,Mendel R.R.
The neurotransmitter receptor-anchoring protein gephyrin reconstitutes molybdenum cofactor biosynthesis in bacteria, plants, and mammalian cells.
Proc. Natl. Acad. Sci. U.S.A.
96
1333-1338
1999
421822
Rees M.I.,Harvey K.,Ward H.,White J.H.,Evans L.,Duguid I.C.,Hsu C.-C.,Coleman S.L.,Miller J.,Baer K.,Waldvogel H.J.,Gibbon F.,Smart T.G.,Owen M.J.,Harvey R.J.,Snell R.G.
Isoform heterogeneity of the human gephyrin gene (GPHN), binding domains to the glycine receptor, and mutation analysis in hyperekplexia.
J. Biol. Chem.
278
24688-24696
2003
421823
Lundby A.,Secher A.,Lage K.,Nordsborg N.B.,Dmytriyev A.,Lundby C.,Olsen J.V.
Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.
Nat. Commun.
3
876-876
2012
421824
Sola M.,Kneussel M.,Heck I.S.,Betz H.,Weissenhorn W.
X-ray crystal structure of the trimeric N-terminal domain of gephyrin.
J. Biol. Chem.
276
25294-25301
2001
421825
Kim E.Y.,Schrader N.,Smolinsky B.,Bedet C.,Vannier C.,Schwarz G.,Schindelin H.
Deciphering the structural framework of glycine receptor anchoring by gephyrin.
EMBO J.
25
1385-1395
2006
421826
Maric H.M.,Kasaragod V.B.,Schindelin H.
Modulation of gephyrin-glycine receptor affinity by multivalency.
ACS Chem. Biol.
9
2554-2562
2014
421827
Maric H.M.,Kasaragod V.B.,Hausrat T.J.,Kneussel M.,Tretter V.,Stromgaard K.,Schindelin H.
Molecular basis of the alternative recruitment of GABA(A) versus glycine receptors through gephyrin.
Nat. Commun.
5
5767-5767
2014