Sequence of CPG2_PORG3
EC Number:3.4.22.37
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
gingipain R
B2RKU0
Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / CIP 103683 / JCM 12257 / NCTC 11834 / 2561)
736
80930
Reaction
hydrolysis of proteins and small molecule substrates, with a preference for Arg in P1
Other sequences found for EC No. 3.4.22.37
General information:
Sequence
0 MKKNFSRIVS IVAFSSLLGG MAFAQPAERG RNPQVRLLSA EQSMSKVQFR MDNLQFTDVQ
60 TSKGVAQVPT FTEGVNISEK GTPILPILSR SLAVSETRAM KVEVVSSKFI EKKDVLIAPS
120 KGVISRAENP DQIPYVYGQS YNEDKFFPGE IATLSDPFIL RDVRGQVVNF APLQYNPVTK
180 TLRIYTEIVV AVSETAEAGQ NTISLVKNST FTGFEDIYKS VFMNYEATRY TPVEEKENGR
240 MIVIVAKKYE GDIKDFVDWK NQRGLRTEVK VAEDIASPVT ANAIQQFVKQ EYEKEGNDLT
300 YVLLVGDHKD IPAKITPGIK SDQVYGQIVG NDHYNEVFIG RFSCESKEDL KTQIDRTIHY
360 ERNITTEDKW LGQALCIASA EGGPSADNGE SDIQHENVIA NLLTQYGYTK IIKCYDPGVT
420 PKNIIDAFNG GISLVNYTGH GSETAWGTSH FGTTHVKQLT NSNQLPFIFD VACVNGDFLF
480 SMPCFAEALM RAQKDGKPTG TVAIIASTIN QSWASPMRGQ DEMNEILCEK HPNNIKRTFG
540 GVTMNGMFAM VEKYKKDGEK MLDTWTVFGD PSLLVRTLVP TEMQVTAPAN ISASAQTFEV
600 ACDYNGAIAT LSDDGDMVGT AIVKDGKAII KLNESIADET NLTLTVVGYN KVTVIKDVKV
660 EGTSIADVAN DKPYTVAVSG KTITVESPAA GLTIFDMNGR RVATAKNRMV FEAQNGVYAV
720 RIATEGKTYT EKVIVK
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
404719
Naito M.,Hirakawa H.,Yamashita A.,Ohara N.,Shoji M.,Yukitake H.,Nakayama K.,Toh H.,Yoshimura F.,Kuhara S.,Hattori M.,Hayashi T.,Nakayama K.
Determination of the genome sequence of Porphyromonas gingivalis strain ATCC 33277 and genomic comparison with strain W83 revealed extensive genome rearrangements in P. gingivalis.
DNA Res.
15
215-225
2008
404720
Kadowaki T.,Nakayama K.,Yoshimura F.,Okamoto K.,Abe N.,Yamamoto K.
Arg-gingipain acts as a major processing enzyme for various cell surface proteins in Porphyromonas gingivalis.
J. Biol. Chem.
273
29072-29076
1998
