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Sequence of BIOI_BACSU

EC Number:1.14.14.46

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
pimeloyl-[acyl-carrier protein] synthase
P53554
Bacillus subtilis (strain 168)
395
44865
Reaction
a (7R,8R)-7,8-dihydroxy-long-chain-acyl-[acyl-carrier protein] + reduced flavodoxin + O2 = a 7-oxoheptanoyl-[acyl-carrier protein] + an n-alkanal + oxidized flavodoxin + 2 H2O
Other sequences found for EC No. 1.14.14.46

General information:

Sequence
show sequence in fasta format
  0 MTIASSTASS EFLKNPYSFY DTLRAVHPIY KGSFLKYPGW YVTGYEETAA ILKDARFKVR
 60 TPLPESSTKY QDLSHVQNQM MLFQNQPDHR RLRTLASGAF TPRTTESYQP YIIETVHHLL
120 DQVQGKKKME VISDFAFPLA SFVIANIIGV PEEDREQLKE WAASLIQTID FTRSRKALTE
180 GNIMAVQAMA YFKELIQKRK RHPQQDMISM LLKGREKDKL TEEEAASTCI LLAIAGHETT
240 VNLISNSVLC LLQHPEQLLK LRENPDLIGT AVEECLRYES PTQMTARVAS EDIDICGVTI
300 RQGEQVYLLL GAANRDPSIF TNPDVFDITR SPNPHLSFGH GHHVCLGSSL ARLEAQIAIN
360 TLLQRMPSLN LADFEWRYRP LFGFRALEEL PVTFE
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
395383
Bower S.,Perkins J.B.,Yocum R.R.,Howitt C.L.,Rahaim P.,Pero J.
Cloning, sequencing, and characterization of the Bacillus subtilis biotin biosynthetic operon.
J. Bacteriol.
178
4122-4130
1996
395384
Lapidus A.,Galleron N.,Sorokin A.,Ehrlich S.D.
Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region.
Microbiology
143
3431-3441
1997
395385
Kunst F.,Ogasawara N.,Moszer I.,Albertini A.M.,Alloni G.,Azevedo V.,Bertero M.G.,Bessieres P.,Bolotin A.,Borchert S.,Borriss R.,Boursier L.,Brans A.,Braun M.,Brignell S.C.,Bron S.,Brouillet S.,Bruschi C.V.,Caldwell B.,Capuano V.,Carter N.M.,Choi S.-K.,Codani J.-J.,Connerton I.F.,Cummings N.J.,Daniel R.A.,Denizot F.,Devine K.M.,Duesterhoeft A.,Ehrlich S.D.,Emmerson P.T.,Entian K.-D.,Errington J.,Fabret C.,Ferrari E.,Foulger D.,Fritz C.,Fujita M.,Fujita Y.,Fuma S.,Galizzi A.,Galleron N.,Ghim S.-Y.,Glaser P.,Goffeau A.,Golightly E.J.,Grandi G.,Guiseppi G.,Guy B.J.,Haga K.,Haiech J.,Harwood C.R.,Henaut A.,Hilbert H.,Holsappel S.,Hosono S.,Hullo M.-F.,Itaya M.,Jones L.-M.,Joris B.,Karamata D.,Kasahara Y.,Klaerr-Blanchard M.,Klein C.,Kobayashi Y.,Koetter P.,Koningstein G.,Krogh S.,Kumano M.,Kurita K.,Lapidus A.,Lardinois S.,Lauber J.,Lazarevic V.,Lee S.-M.,Levine A.,Liu H.,Masuda S.,Mauel C.,Medigue C.,Medina N.,Mellado R.P.,Mizuno M.,Moestl D.,Nakai S.,Noback M.,Noone D.,O'Reilly M.,Ogawa K.,Ogiwara A.,Oudega B.,Park S.-H.,Parro V.,Pohl T.M.,Portetelle D.,Porwollik S.,Prescott A.M.,Presecan E.,Pujic P.,Purnelle B.,Rapoport G.,Rey M.,Reynolds S.,Rieger M.,Rivolta C.,Rocha E.,Roche B.,Rose M.,Sadaie Y.,Sato T.,Scanlan E.,Schleich S.,Schroeter R.,Scoffone F.,Sekiguchi J.,Sekowska A.,Seror S.J.,Serror P.,Shin B.-S.,Soldo B.,Sorokin A.,Tacconi E.,Takagi T.,Takahashi H.,Takemaru K.,Takeuchi M.,Tamakoshi A.,Tanaka T.,Terpstra P.,Tognoni A.,Tosato V.,Uchiyama S.,Vandenbol M.,Vannier F.,Vassarotti A.,Viari A.,Wambutt R.,Wedler E.,Wedler H.,Weitzenegger T.,Winters P.,Wipat A.,Yamamoto H.,Yamane K.,Yasumoto K.,Yata K.,Yoshida K.,Yoshikawa H.-F.,Zumstein E.,Yoshikawa H.,Danchin A.
The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.
Nature
390
249-256
1997
395386
Stok J.E.,De Voss J.
Expression, purification, and characterization of BioI: a carbon-carbon bond cleaving cytochrome P450 involved in biotin biosynthesis in Bacillus subtilis.
Arch. Biochem. Biophys.
384
351-360
2000
395387
Green A.J.,Rivers S.L.,Cheeseman M.,Reid G.A.,Quaroni L.G.,Macdonald I.D.G.,Chapman S.K.,Munro A.W.
Expression, purification and characterization of cytochrome P450 Biol: a novel P450 involved in biotin synthesis in Bacillus subtilis.
J. Biol. Inorg. Chem.
6
523-533
2001
395388
Lawson R.J.,Leys D.,Sutcliffe M.J.,Kemp C.A.,Cheesman M.R.,Smith S.J.,Clarkson J.,Smith W.E.,Haq I.,Perkins J.B.,Munro A.W.
Thermodynamic and biophysical characterization of cytochrome P450 BioI from Bacillus subtilis.
Biochemistry
43
12410-12426
2004
395389
Cryle M.J.,De Voss J.J.
Carbon-carbon bond cleavage by cytochrome p450(BioI)(CYP107H1).
Chem. Commun. (Camb.)
7
86-87
2004
395390
Cryle M.J.,Schlichting I.
Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex.
Proc. Natl. Acad. Sci. U.S.A.
105
15696-15701
2008