Sequence of TOP2_PLAFK
EC Number:5.6.2.2
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
DNA topoisomerase (ATP-hydrolysing)
P41001
Plasmodium falciparum (isolate K1 / Thailand)
1398
161029
Reaction
ATP-dependent breakage, passage and rejoining of double-stranded DNA
Other sequences found for EC No. 5.6.2.2
General information:
Sequence
0 MAKNKTIEER YQKKSQIEHI LLRPDTYIGS VEMHTQLLWV WNKEKNRMVQ KNITYVPGLY
60 KIFDEIIVNA ADVKAREKEK SENPMTCIKI EINKENKRIS VYNDGEGIPV DIHKEMNIYV
120 PHMIFGELLT SDNYDDAEDR ITGGRNGFGA KLTNIFSKEF IVQCGDSSRK KEFKMTWSDN
180 MSKFSEPHIK NYNGKDYVKV TFKPDLNKFG MTEMDDDIES LLFKRVYDLA GTCSVRVYLN
240 GQRLAVKDFK SYVDLYLKDN SNDNKNNKGQ NDNNNNNNNN NDENANQNND NLDVSLSNEP
300 ADGTPTKNNN NNNNNNDEDE IVKIHEKQHR WEIVVSKSDG SQFQQVSFVN SICTTKGGSH
360 VNYIVEQLLS SLSKKANAKN KGGMEIKSGH IRNHLWVFVN CLIVNPTFDS QTKETLTTKP
420 VKFGSKCILS DKTINNVLKS PILSNILLWA QAKAQVELKK KMKAGSSKAR ERIIGIPKLE
480 DANDAGSKYS QECTLILTEG DSAKTSCLAG LSIVGRDKYG VFPLKGKLLN VRDASFKQLM
540 DNKEIQNIFR IMGLDITDKN KDDIKGLRYG SLMIMTDQDY DGSHIKGLLI NMIHKFWPSL
600 LKHKGFLSEF VTPIVKVQKG SQEYSFFTIA EYEQWKENTN LLGWKIKYYK GLGTSTDREF
660 KQYFSDIKNH KIMFLWTGDR DGDSIDMAFS KKRIEDRKLW LQNFILGSYV DHKEKDLSYY
720 DFVNKELIYY SRYDTERSIP NIMDGWKPGQ RKVLYGCFKR NLRNECKVAQ LVGYIAEHSA
780 YHHHGESSLQ QTIINMAQTF VGSNNINFLE PCGQFGSRKE GGKDASAARY IFTKLASSTR
840 SIFNEYDDPI LKYLNEEGQK IEPQYYIPVI PTILVNGCEG IGTGYSSFIP NYNYKDIIDN
900 IKRYINKEPL IPMVPWYKDF KGRIESNGKT GYETIGIINK IDNDTLEITE LPIKKWTQDY
960 KEFLEELLTD EKHQLILDYI DNSSHEDICF TIKMDPAKLQ KAEEEGLEKV FKLKSTLTTT
1020 NMTLFDPNLK LQRYSTELDI LKEFCYQRLK AYENRKSYLI SKLEKEKRII SNKTKFILAI
1080 VNNELIVNKK KKKVLVEELY RKGYDPYKDI NKIKKEEIFE QELLDAADNP EDNEEIIAGI
1140 TVKDYDYLLS MPIFSLTLEK VEDLLTQLKE KERELEILRN ITVETMWLKD IEKVEEAIEF
1200 QRNVELSNRE ESNKFKVARK QGPSSMKKKK KKKKLSSDEE SEGGDTSDSS EFLVNTLNIK
1260 KNTNKKTTTS SNNVNNSKKR LRKADDLNSN ELDNTLSVSK TFDDNNNLTD NTPLINRLND
1320 ENNEFSSNNV DNKSTNKNSR KKKPKIADST NDNNSELNSS IQINDNVNDD INITISPNKT
1380 INVNEFSSIK NKLLELGI
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
368673
Cheesman S.,McAleese S.,Goman M.,Johnson D.,Horrocks P.,Ridley R.G.,Kilbey B.J.
The gene encoding topoisomerase II from Plasmodium falciparum.
Nucleic Acids Res.
22
2547-2551
1994
