Sequence of FTMC_ASPFM
EC Number:1.14.14.118
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
tryprostatin B + [reduced NADPH-hemoprotein reductase] + O2 = 6-hydroxytryprostatin B + [oxidized NADPH-hemoprotein reductase] + H2O
Other sequences found for EC No. 1.14.14.118
General information:
Sequence
0 MKPSHSDTPL MMPSVMKCGY LATAGLIGIC THLSYFRYGE HHLYPWRYVR FHLCLTMGVA
60 ALLYAKKPPQ YTLCSMDLVK DVSLLMATYL VGLFASLLLY RTLFHPLRQI RGPWAAKISS
120 FWLSFRLRRG PSFRILHELH EEYGPVVRVG PSEVSIIHPE AVRMIYGPNS RCSKNTFYDN
180 GHPMMSLHSY RDRIAHDQRR RVWSAGFGDR ALRGYEQRMR VYRQKLFQRL EARAVAESAI
240 NISQWFNFYS YDTMGDLAFA RSFDMLDASR NHWAVDMLMH GMIGYRYLFP SWFFRLLATM
300 PSLSSDWHKF IGFATDTMLR RVGEQVDVPD IFASLLAPLN GREPTEDERN MLMGDAMLII
360 TAGSDTTATS LTSIVYELAR HLDEVDKLRA ELDPIEADSD GEYQHDTLAK LPHLNGFINE
420 TLRLHPPIPG VIPRKTPPEG IHVKDVFIPG NMTVFSPQWS MGRSEAAYID PEIFNPERWY
480 KHMDLVKDPS AFAPFSIGPY SCIGKPLALM NIRTTVARLI MSFDVRFPEG EDGIRWMDAA
540 DEHFAMGIHQ MPVVLTRRH
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
35397
Kato N.,Suzuki H.,Takagi H.,Asami Y.,Kakeya H.,Uramoto M.,Usui T.,Takahashi S.,Sugimoto Y.,Osada H.
Identification of cytochrome P450s required for fumitremorgin biosynthesis in Aspergillus fumigatus.
ChemBioChem
10
920-928
2009
35398
Grundmann A.,Li S.M.
Overproduction, purification and characterization of FtmPT1, a brevianamide F prenyltransferase from Aspergillus fumigatus.
Microbiology
151
2199-2207
2005
35399
Maiya S.,Grundmann A.,Li S.M.,Turner G.
The fumitremorgin gene cluster of Aspergillus fumigatus: identification of a gene encoding brevianamide F synthetase.
ChemBioChem
7
1062-1069
2006
35400
Grundmann A.,Kuznetsova T.,Afiyatullov S.S.,Li S.M.
FtmPT2, an N-prenyltransferase from Aspergillus fumigatus, catalyses the last step in the biosynthesis of fumitremorgin B.
ChemBioChem
9
2059-2063
2008
35401
Steffan N.,Grundmann A.,Afiyatullov S.,Ruan H.,Li S.M.
FtmOx1, a non-heme Fe(II) and alpha-ketoglutarate-dependent dioxygenase, catalyses the endoperoxide formation of verruculogen in Aspergillus fumigatus.
Org. Biomol. Chem.
7
4082-4087
2009
35402
Jost M.,Zocher G.,Tarcz S.,Matuschek M.,Xie X.,Li S.M.,Stehle T.
Structure-function analysis of an enzymatic prenyl transfer reaction identifies a reaction chamber with modifiable specificity.
J. Am. Chem. Soc.
132
17849-17858
2010
35403
Wollinsky B.,Ludwig L.,Xie X.,Li S.M.
Breaking the regioselectivity of indole prenyltransferases: identification of regular C3-prenylated hexahydropyrrolo[2,3-b]indoles as side products of the regular C2-prenyltransferase FtmPT1.
Org. Biomol. Chem.
10
9262-9270
2012
35404
Kato N.,Suzuki H.,Okumura H.,Takahashi S.,Osada H.
A point mutation in ftmD blocks the fumitremorgin biosynthetic pathway in Aspergillus fumigatus strain Af293.
Biosci. Biotechnol. Biochem.
77
1061-1067
2013
