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Sequence of AEP_YARLI

EC Number:3.4.21.62

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Subtilisin
P09230
Yarrowia lipolytica (strain CLIB 122 / E 150)
454
46906
Reaction
Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyses peptide amides
Other sequences found for EC No. 3.4.21.62

General information:

Sequence
show sequence in fasta format
  0 MKLATAFTIL TAVLAAPLAA PAPAPDAAPA AVPEGPAAAA YSSILSVVAK QSKKFKHHKR
 60 DLDEKDQFIV VFDSSATVDQ IASEIQKLDS LVDEDSSNGI TSALDLPVYT DGSGFLGFVG
120 KFNSTIVDKL KESSVLTVEP DTIVSLPEIP ASSNAKRAIQ TTPVTQWGLS RISHKKAQTG
180 NYAYVRETVG KHPTVSYVVD SGIRTTHSEF GGRAVWGANF ADTQNADLLG HGTHVAGTVG
240 GKTYGVDANT KLVAVKVFAG RSAALSVINQ GFTWALNDYI SKRDTLPRGV LNFSGGGPKS
300 ASQDALWSRA TQEGLLVAIA AGNDAVDACN DSPGNIGGST SGIITVGSID SSDKISVWSG
360 GQGSNYGTCV DVFAPGSDII SASYQSDSGT LVYSGTSMAC PHVAGLASYY LSINDEVLTP
420 AQVEALITES NTGVLPTTNL KGSPNAVAYN GVGI
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
2837
Davidow L.S.,O'Donnell M.M.,Kaczmarek F.S.,Pereira D.A.,Dezeeuw J.R.,Franke A.E.
Cloning and sequencing of the alkaline extracellular protease gene of Yarrowia lipolytica.
J. Bacteriol.
169
4621-4629
1987
2838
Matoba S.,Fukayama J.,Wing R.A.,Ogrydziak D.M.
Intracellular precursors and secretion of alkaline extracellular protease of Yarrowia lipolytica.
Mol. Cell. Biol.
8
4904-4916
1988
2839
Dujon B.,Sherman D.,Fischer G.,Durrens P.,Casaregola S.,Lafontaine I.,de Montigny J.,Marck C.,Neuveglise C.,Talla E.,Goffard N.,Frangeul L.,Aigle M.,Anthouard V.,Babour A.,Barbe V.,Barnay S.,Blanchin S.,Beckerich J.-M.,Beyne E.,Bleykasten C.,Boisrame A.,Boyer J.,Cattolico L.,Confanioleri F.,de Daruvar A.,Despons L.,Fabre E.,Fairhead C.,Ferry-Dumazet H.,Groppi A.,Hantraye F.,Hennequin C.,Jauniaux N.,Joyet P.,Kachouri R.,Kerrest A.,Koszul R.,Lemaire M.,Lesur I.,Ma L.,Muller H.,Nicaud J.-M.,Nikolski M.,Oztas S.,Ozier-Kalogeropoulos O.,Pellenz S.,Potier S.,Richard G.-F.,Straub M.-L.,Suleau A.,Swennen D.,Tekaia F.,Wesolowski-Louvel M.,Westhof E.,Wirth B.,Zeniou-Meyer M.,Zivanovic Y.,Bolotin-Fukuhara M.,Thierry A.,Bouchier C.,Caudron B.,Scarpelli C.,Gaillardin C.,Weissenbach J.,Wincker P.,Souciet J.-L.
Genome evolution in yeasts.
Nature
430
35-44
2004
2840
Ogrydziak D.M.,Scharf S.J.
Alkaline extracellular protease produced by Saccharomycopsis lipolytica CX161-1B.
J. Gen. Microbiol.
128
1225-1234
1982
2841
Ogrydziak D.M.,Demain A.L.,Tannenbaum S.R.
Regulation of extracellular protease production in Candida lipolytica.
Biochim. Biophys. Acta
497
525-538
1977
2842
Simms P.C.,Ogrydziak D.M.
Structural gene for the alkaline extracellular protease of Saccharomycopsis lipolytica.
J. Bacteriol.
145
404-409
1981
2843
Matoba S.,Ogrydziak D.M.
A novel location for dipeptidyl aminopeptidase processing sites in the alkaline extracellular protease of Yarrowia lipolytica.
J. Biol. Chem.
264
6037-6043
1989
2844
Fabre E.,Nicaud J.-M.,Lopez M.C.,Gaillardin C.
Role of the proregion in the production and secretion of the Yarrowia lipolytica alkaline extracellular protease.
J. Biol. Chem.
266
3782-3790
1991
2845
Fabre E.,Tharaud C.,Gaillardin C.
Intracellular transit of a yeast protease is rescued by trans-complementation with its prodomain.
J. Biol. Chem.
267
15049-15055
1992
2846
Le Dall M.T.,Nicaud J.M.,Gaillardin C.
Multiple-copy integration in the yeast Yarrowia lipolytica.
Curr. Genet.
26
38-44
1994
2847
Blanchin-Roland S.,Cordero Otero R.R.,Gaillardin C.
Two upstream activation sequences control the expression of the XPR2 gene in the yeast Yarrowia lipolytica.
Mol. Cell. Biol.
14
327-338
1994
2848
Enderlin C.S.,Ogrydziak D.M.
Cloning, nucleotide sequence and functions of XPR6, which codes for a dibasic processing endoprotease from the yeast Yarrowia lipolytica.
Yeast
10
67-79
1994
2849
Mamoun C.B.,Beckerich J.M.,Gaillardin C.
The TSR1 gene of Yarrowia lipolytica is involved in the signal recognition particle-dependent translocation pathway of secretory proteins.
J. Biol. Chem.
271
23895-23901
1996
2850
Otero R.C.,Gaillardin C.
Dominant mutations affecting expression of pH-regulated genes in Yarrowia lipolytica.
Mol. Gen. Genet.
252
311-319
1996
2851
Glover D.J.,McEwen R.K.,Thomas C.R.,Young T.W.
pH-regulated expression of the acid and alkaline extracellular proteases of Yarrowia lipolytica.
Microbiology
143
3045-3054
1997
2852
Matoba S.,Morano K.A.,Klionsky D.J.,Kim K.,Ogrydziak D.M.
Dipeptidyl aminopeptidase processing and biosynthesis of alkaline extracellular protease from Yarrowia lipolytica.
Microbiology
143
3263-3272
1997
2853
Lambert M.,Blanchin-Roland S.,Le Louedec F.,Lepingle A.,Gaillardin C.
Genetic analysis of regulatory mutants affecting synthesis of extracellular proteinases in the yeast Yarrowia lipolytica: identification of a RIM101/pacC homolog.
Mol. Cell. Biol.
17
3966-3976
1997
2854
Madzak C.,Blanchin-Roland S.,Cordero-Otero R.R.,Gaillardin C.
Functional analysis of upstream regulating regions from the Yarrowia lipolytica XPR2 promoter.
Microbiology
145
75-87
1999
2855
Gonzalez-Lopez C.I.,Szabo R.,Blanchin-Roland S.,Gaillardin C.
Genetic control of extracellular protease synthesis in the yeast Yarrowia lipolytica.
Genetics
160
417-427
2002
2856
Poza M.,Sestelo A.B.,Ageitos J.M.,Vallejo J.A.,Veiga-Crespo P.,Villa T.G.
Cloning and expression of the XPR2 gene from Yarrowia lipolytica in Pichia pastoris.
J. Agric. Food Chem.
55
3944-3948
2007
2857
Ogrydziak D.M.,Nicaud J.M.
Characterization of Yarrowia lipolytica XPR2 multi-copy strains over-producing alkaline extracellular protease - a system for rapidly increasing secretory pathway cargo loads.
FEMS Yeast Res.
12
938-948
2012