Sequence of EZH2_MOUSE

[histone H3]-lysine27 N-trimethyltransferase

Q61188

746

85292

32012

Hobert O.,Sures I.,Ciossek T.,Fuchs M.,Ullrich A.

Isolation and developmental expression analysis of Enx-1, a novel mouse Polycomb group gene.

Mech. Dev.

55

171-184

1996

32014

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res.

14

2121-2127

2004

32015

Laible G.,Haynes A.R.,Lebersorger A.,O'Carroll D.,Mattei M.-G.,Denny P.,Brown S.D.M.,Jenuwein T.

The murine polycomb-group genes ezh1 and ezh2 map close to hox gene clusters on mouse chromosomes 11 and 6.

Mamm. Genome

10

311-314

1999

32016

Denisenko O.N.,Shnyreva M.,Suzuki H.,Bomsztyk K.

Point mutations in the WD40 domain of Eed block its interaction with Ezh2.

Mol. Cell. Biol.

18

5634-5642

1998

32017

O'Carroll D.,Erhardt S.,Pagani M.,Barton S.C.,Surani M.A.,Jenuwein T.

The polycomb-group gene Ezh2 is required for early mouse development.

Mol. Cell. Biol.

21

4330-4336

2001

32018

Mak W.,Baxter J.,Silva J.,Newall A.E.,Otte A.P.,Brockdorff N.

Mitotically stable association of polycomb group proteins Eed and Enx1 with the inactive X chromosome in trophoblast stem cells.

Curr. Biol.

12

1016-1020

2002

32019

Silva J.,Mak W.,Zvetkova I.,Appanah R.,Nesterova T.B.,Webster Z.,Peters A.H.F.M.,Jenuwein T.,Otte A.P.,Brockdorff N.

Establishment of histone H3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes.

Dev. Cell

4

481-495

2003

32020

Plath K.,Fang J.,Mlynarczyk-Evans S.K.,Cao R.,Worringer K.A.,Wang H.,de la Cruz C.C.,Otte A.P.,Panning B.,Zhang Y.

Role of histone H3 lysine 27 methylation in X inactivation.

Science

300

131-135

2003

32021

Caretti G.,Di Padova M.,Micales B.,Lyons G.E.,Sartorelli V.

The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation.

Genes Dev.

18

2627-2638

2004

32023

Umlauf D.,Goto Y.,Cao R.,Cerqueira F.,Wagschal A.,Zhang Y.,Feil R.

Imprinting along the Kcnq1 domain on mouse chromosome 7 involves repressive histone methylation and recruitment of Polycomb group complexes.

Nat. Genet.

36

1296-1300

2004

32024

Mak W.,Nesterova T.B.,de Napoles M.,Appanah R.,Yamanaka S.,Otte A.P.,Brockdorff N.

Reactivation of the paternal X chromosome in early mouse embryos.

Science

303

666-669

2004

32025

Kuzmichev A.,Margueron R.,Vaquero A.,Preissner T.S.,Scher M.,Kirmizis A.,Ouyang X.,Brockdorff N.,Abate-Shen C.,Farnham P.J.,Reinberg D.

Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation.

Proc. Natl. Acad. Sci. U.S.A.

102

1859-1864

2005

32026

Etchegaray J.P.,Yang X.,DeBruyne J.P.,Peters A.H.,Weaver D.R.,Jenuwein T.,Reppert S.M.

The polycomb group protein EZH2 is required for mammalian circadian clock function.

J. Biol. Chem.

281

21209-21215

2006

32027

Kalantry S.,Mills K.C.,Yee D.,Otte A.P.,Panning B.,Magnuson T.

The Polycomb group protein Eed protects the inactive X-chromosome from differentiation-induced reactivation.

Nat. Cell Biol.

8

195-202

2006

32028

Bracken A.P.,Kleine-Kohlbrecher D.,Dietrich N.,Pasini D.,Gargiulo G.,Beekman C.,Theilgaard-Moench K.,Minucci S.,Porse B.T.,Marine J.-C.,Hansen K.H.,Helin K.

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells.

Genes Dev.

21

525-530

2007

32029

Kim S.Y.,Levenson J.M.,Korsmeyer S.,Sweatt J.D.,Schumacher A.

Developmental regulation of Eed complex composition governs a switch in global histone modification in brain.

J. Biol. Chem.

282

9962-9972

2007

32030

Wong C.F.,Tellam R.L.

MicroRNA-26a targets the histone methyltransferase Enhancer of Zeste homolog 2 during myogenesis.

J. Biol. Chem.

283

9836-9843

2008

32031

Shen X.,Liu Y.,Hsu Y.-J.,Fujiwara Y.,Kim J.,Mao X.,Yuan G.-C.,Orkin S.H.

EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency.

Mol. Cell

32

491-502

2008

32032

Margueron R.,Li G.,Sarma K.,Blais A.,Zavadil J.,Woodcock C.L.,Dynlacht B.D.,Reinberg D.

Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms.

Mol. Cell

32

503-518

2008

32033

Cao R.,Wang H.,He J.,Erdjument-Bromage H.,Tempst P.,Zhang Y.

Role of hPHF1 in H3K27 methylation and Hox gene silencing.

Mol. Cell. Biol.

28

1862-1872

2008

32034

Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.

A tissue-specific atlas of mouse protein phosphorylation and expression.

Cell

143

1174-1189

2010

32035

Walker E.,Chang W.Y.,Hunkapiller J.,Cagney G.,Garcha K.,Torchia J.,Krogan N.J.,Reiter J.F.,Stanford W.L.

Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation.

Cell Stem Cell

6

153-166

2010

32036

Neri F.,Krepelova A.,Incarnato D.,Maldotti M.,Parlato C.,Galvagni F.,Matarese F.,Stunnenberg H.G.,Oliviero S.

Dnmt3L antagonizes DNA methylation at bivalent promoters and favors DNA methylation at gene bodies in ESCs.

Cell

155

121-134

2013

32037

Nguyen K.D.,Fentress S.J.,Qiu Y.,Yun K.,Cox J.S.,Chawla A.

Circadian gene Bmal1 regulates diurnal oscillations of Ly6C(hi) inflammatory monocytes.

Science

341

1483-1488

2013

32038

Ragazzini R.,Perez-Palacios R.,Baymaz I.H.,Diop S.,Ancelin K.,Zielinski D.,Michaud A.,Givelet M.,Borsos M.,Aflaki S.,Legoix P.,Jansen P.W.T.C.,Servant N.,Torres-Padilla M.E.,Bourc'his D.,Fouchet P.,Vermeulen M.,Margueron R.

EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells.

Nat. Commun.

10

3858-3858

2019

32039

Han Z.,Xing X.,Hu M.,Zhang Y.,Liu P.,Chai J.

Structural basis of EZH2 recognition by EED.

Structure

15

1306-1315

2007