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Sequence of DPEP1_HUMAN

EC Number:3.4.13.19

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
membrane dipeptidase
P16444
Homo sapiens
411
45674
Reaction
hydrolysis of dipeptides
Other sequences found for EC No. 3.4.13.19

General information:

Sequence
show sequence in fasta format
  0 MWSGWWLWPL VAVCTADFFR DEAERIMRDS PVIDGHNDLP WQLLDMFNNR LQDERANLTT
 60 LAGTHTNIPK LRAGFVGGQF WSVYTPCDTQ NKDAVRRTLE QMDVVHRMCR MYPETFLYVT
120 SSAGIRQAFR EGKVASLIGV EGGHSIDSSL GVLRALYQLG MRYLTLTHSC NTPWADNWLV
180 DTGDSEPQSQ GLSPFGQRVV KELNRLGVLI DLAHVSVATM KATLQLSRAP VIFSHSSAYS
240 VCASRRNVPD DVLRLVKQTD SLVMVNFYNN YISCTNKANL SQVADHLDHI KEVAGARAVG
300 FGGDFDGVPR VPEGLEDVSK YPDLIAELLR RNWTEAEVKG ALADNLLRVF EAVEQASNLT
360 QAPEEEPIPL DQLGGSCRTH YGYSSGASSL HRHWGLLLAS LAPLVLCLSL L
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
26839
Satoh S.,Kusunoki C.,Konta Y.,Niwa M.,Kohsaka M.
Cloning and structural analysis of genomic DNA for human renal dipeptidase.
Biochim. Biophys. Acta
1172
181-183
1993
26840
Adachi H.,Tawaragi Y.,Inuzuka C.,Kubota I.,Tsujimoto M.,Nishihara T.,Nakazato H.
Primary structure of human microsomal dipeptidase deduced from molecular cloning.
J. Biol. Chem.
265
3992-3995
1990
26841
Satoh S.,Ohtsuka K.,Keida Y.,Kusunoki C.,Konta Y.,Niwa M.,Kohsaka M.
Gene structural analysis and expression of human renal dipeptidase.
Biotechnol. Prog.
10
134-140
1994
26844
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
26845
Hooper N.M.,Keen J.N.,Turner A.J.
Characterization of the glycosyl-phosphatidylinositol-anchored human renal dipeptidase reveals that it is more extensively glycosylated than the pig enzyme.
Biochem. J.
265
429-433
1990
26846
Adachi H.,Kubota I.,Okamura N.,Iwata H.,Tsujimoto M.,Nakazato H.,Nishihara T.,Noguchi T.
Purification and characterization of human microsomal dipeptidase.
J. Biochem.
105
957-961
1989
26847
Zhang Z.,Henzel W.J.
Signal peptide prediction based on analysis of experimentally verified cleavage sites.
Protein Sci.
13
2819-2824
2004
26848
Campbell B.J.,Forrester L.J.,Zahler W.L.,Burks M.
Beta-lactamase activity of purified and partially characterized human renal dipeptidase.
J. Biol. Chem.
259
14586-14590
1984
26849
Adachi H.,Katayama T.,Inuzuka C.,Oikawa S.,Tsujimoto M.,Nakazato H.
Identification of membrane anchoring site of human renal dipeptidase and construction and expression of a cDNA for its secretory form.
J. Biol. Chem.
265
15341-15345
1990
26850
Adachi H.,Katayama T.,Nakazato H.,Tsujimoto M.
Importance of Glu-125 in the catalytic activity of human renal dipeptidase.
Biochim. Biophys. Acta
1163
42-48
1993
26851
Chen R.,Jiang X.,Sun D.,Han G.,Wang F.,Ye M.,Wang L.,Zou H.
Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
J. Proteome Res.
8
651-661
2009
26852
Nitanai Y.,Satow Y.,Adachi H.,Tsujimoto M.
Crystal structure of human renal dipeptidase involved in beta-lactam hydrolysis.
J. Mol. Biol.
321
177-184
2002
26853
Sjoeblom T.,Jones S.,Wood L.D.,Parsons D.W.,Lin J.,Barber T.D.,Mandelker D.,Leary R.J.,Ptak J.,Silliman N.,Szabo S.,Buckhaults P.,Farrell C.,Meeh P.,Markowitz S.D.,Willis J.,Dawson D.,Willson J.K.V.,Gazdar A.F.,Hartigan J.,Wu L.,Liu C.,Parmigiani G.,Park B.H.,Bachman K.E.,Papadopoulos N.,Vogelstein B.,Kinzler K.W.,Velculescu V.E.
The consensus coding sequences of human breast and colorectal cancers.
Science
314
268-274
2006
26854
Tachibana K.,Saito M.,Imai J.I.,Ito E.,Yanagisawa Y.,Honma R.,Saito K.,Ando J.,Momma T.,Ohki S.,Ohtake T.,Watanabe S.,Waguri S.,Takenoshita S.
Clinicopathological examination of dipeptidase 1 expression in colorectal cancer.
Biomed. Rep.
6
423-428
2017
26855
Choudhury S.R.,Babes L.,Rahn J.J.,Ahn B.Y.,Goring K.R.,King J.C.,Lau A.,Petri B.,Hao X.,Chojnacki A.K.,Thanabalasuriar A.,McAvoy E.F.,Tabaries S.,Schraeder C.,Patel K.D.,Siegel P.M.,Kopciuk K.A.,Schriemer D.C.,Muruve D.A.,Kelly M.M.,Yipp B.G.,Kubes P.,Robbins S.M.,Senger D.L.
Dipeptidase-1 is an adhesion receptor for neutrophil recruitment in lungs and liver.
Cell
178
1205-1221
2019
26856
Hayashi K.,Longenecker K.L.,Koenig P.,Prashar A.,Hampl J.,Stoll V.,Vivona S.
Structure of human DPEP3 in complex with the SC-003 antibody Fab fragment reveals basis for lack of dipeptidase activity.
J. Struct. Biol.
211
107512-107512
2020