Sequence of DOT1_DEBHA
EC Number:2.1.1.360
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
[histone H3]-lysine79 N-trimethyltransferase
Q6BTC8
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)
1172
135295
Reaction
3 S-adenosyl-L-methionine + a [histone H3]-L-lysine79 = 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine79
Other sequences found for EC No. 2.1.1.360
General information:
Sequence
0 MENIAHHNTT YNITPICSDS SECSSMEMLP LGCKTHSDKS DARRNLMDTG IYTPDSNSDS
60 SDPRSDSSCV DVSNSLAVSH PISFCNWTDE ESSLLTEHIK TDLTSEALTS AFPNKSLALI
120 IRKIHDLQPV LDWTKNEIYL LAGIILNDSN SAIRRHKHKF PCRNVSNLNK KFQHYKNMVR
180 RLNGVDHSKW TKPEIASLIS LIDYDLTKTK LQKELPNKNI EEIKDLTNEM RIHSNFSHVE
240 SVLFEQTMTE NDPIEIVLDQ FPLKNKETCK KRLLKLNELS QHRDMAKRRL DEFESLIQNE
300 LKQIKDSIDL TRLKYLLVND LTGKQLRSSF PGISMKYLKL IAKEMGFDEA GEYTLAEMNF
360 LKKALQENAK LKSIIDELPF RSQLSIETKI NSVEPNRRRS VFTSQVDELL YMAKWYSSDN
420 FGNLSRRRNS RYASKLDKPK DKASDIMQPS KLHLENEEVT EAKVIPHDKG VENMISDHKL
480 KGKNNEQKKR KSKKPTSMVE VLKEESAYFQ SVTGNRCVLK EGQKRKRERL MQIKLETKLK
540 KPKSQNLNET NRIQETKKLM KCDVEPDKVK EQKSFKSENL KEAKLDASDS SIVSDVEISL
600 KKKLNKIENE EKRSPYDPED ISTDTLVPLY GRQLYVNEVY ETQPRPPKLS FREDTNIMVQ
660 NCSEISLTDT IAADIISQHC KNYRDMPISF PSLTIVDRNT NRMILNPMNK IRIRFLLYPQ
720 HSELFILAEP KSNELDPINE IKKLFQLHYS LFFSHSSKLK KIILSEYNKE IDISIEENDF
780 VRFMFVIDKW NRLMVELTPN DVDIGSHDIN EEIRAYLSPN EIKIPSDEDI RLDIFYSEIQ
840 LSTEENPISD NDPIEPSSPS FDLIKSMKRC FTHDSSNRLT PPISSEEDNK ENEPPIESDF
900 RNNNNKGSIP CTPVRLNTRN KMVVNAVKPE NYESNFFRHL KEKTSVSRFC VQQILLRIYS
960 RIVSTESRKL RSYKAFTAEV YGELLPSFTS EVLTKVNLQP QHKFYDLGSG VGNTTFQAAL
1020 EFGVHLSGGC EIMEHASKLT ELQTMLLNKH LALLGLKKLP LNFALSQSFV ENDIVRQAVI
1080 ECDVLLVNNY LFDVNLNTAV GKMLYGLKPG TKIISLRNFI RPRYKASSDK TIFDYLKVER
1140 HEMSNYLSVS WTANKVPYYI STVQENICEE YV
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
26675
Dujon B.,Sherman D.,Fischer G.,Durrens P.,Casaregola S.,Lafontaine I.,de Montigny J.,Marck C.,Neuveglise C.,Talla E.,Goffard N.,Frangeul L.,Aigle M.,Anthouard V.,Babour A.,Barbe V.,Barnay S.,Blanchin S.,Beckerich J.-M.,Beyne E.,Bleykasten C.,Boisrame A.,Boyer J.,Cattolico L.,Confanioleri F.,de Daruvar A.,Despons L.,Fabre E.,Fairhead C.,Ferry-Dumazet H.,Groppi A.,Hantraye F.,Hennequin C.,Jauniaux N.,Joyet P.,Kachouri R.,Kerrest A.,Koszul R.,Lemaire M.,Lesur I.,Ma L.,Muller H.,Nicaud J.-M.,Nikolski M.,Oztas S.,Ozier-Kalogeropoulos O.,Pellenz S.,Potier S.,Richard G.-F.,Straub M.-L.,Suleau A.,Swennen D.,Tekaia F.,Wesolowski-Louvel M.,Westhof E.,Wirth B.,Zeniou-Meyer M.,Zivanovic Y.,Bolotin-Fukuhara M.,Thierry A.,Bouchier C.,Caudron B.,Scarpelli C.,Gaillardin C.,Weissenbach J.,Wincker P.,Souciet J.-L.
Genome evolution in yeasts.
Nature
430
35-44
2004
